[ { "cls_id": "homologset.agr.MGI:1351869", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O35331-1", "uniprot_id": "PDXK_RAT", "id": "O35331-1", "name": "Pyridoxal kinase", "aln": "----MEGECR-VLSIQSHVVRGYVGNRAAMFPLQVLGFEVDAVNSVQFSNHTGY--AHWKGQVLTSQELHALYEGLKANNVN-KYDYVLTGYTRDKSFLGMVVDIVQELKQQNSRLVYVCDPVMGDKWNGEGSMYVPQDLLPVYREKVVP---MADIITPNQFEAELLSGRKIHSQEEAFAVMDVLHRMGPDTVVITSSDLPSPKGSDYLMALGSQRMRKPDGSTVTQRIRMEMRKVDPVFVGTGDLFAAMLLAWTHKHPD----NLKVACEKTVSAMQHVLQRTIRCAKAEAGEGQKPSP------AQLELRMVQSRKDIEDPEIVVQATVL----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0ABK0LEN0-1", "uniprot_id": "A0ABK0LEN0_RAT", "id": "A0ABK0LEN0-1", "name": "Pyridoxal kinase", "aln": "----MSSHYTDSWEMLGWGSWLPWTCRKDLEGRQVLGFEVDAVNSVQFSNHAGY--AHWKGQVLTSQELHALYEGLKANNVN-KYDYVLTGYTRDKSFLTMVVDIVKELKQQNSKLMYVCDPVMGDKRNGEGSMYVPQDLLPVYREKVVP---MADIITPNQFEAELLSGRKIHSQEEAFAVMDVLHRMGPDTVVITSSDLPSPKGSDYLMALGSQRMRKPDGSTVTQRIRMEMRKLDAVFVGTGDLFAAMLLAWTHKHPD----NLKVACEKTVSAMQHVLQRTIRCAKAEAGEGQKPSP------AQLELRMVQSRKDIEDPEIVVQATVL----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8K183-1", "uniprot_id": "PDXK_MOUSE", "id": "Q8K183-1", "name": "Pyridoxal kinase", "aln": "----MEGECR-VLSIQSHVVRGYVGNRAAMFPLQVLGFEVDAVNSVQFSNHTGY--AHWKGQVLKSQELHELYEGLKVNDVN-KYDYVLTGYTRDKSFLAMVVDIVRELKQQNSRLVYVCDPVMGDKWNGEGSMYVPQDLLPVYRDKVVP---VADIITPNQFEAELLSGRKIHSQEEAFEVMDMLHCMGPDTVVITSSDLPSSQGSDYLIALGSQRMRKPDGSTVTQRIRMEMRKVEAVFVGTGDLFAAMLLAWTHKHPD----NLKVACEKTVSAMQHVLQRTIRCAKAEAGEGQKPSP------AQLELRMVQSKRDIEDPEIVVQATVL----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O00764-1", "uniprot_id": "PDXK_HUMAN", "id": "O00764-1", "name": "Pyridoxal kinase", "aln": "----MEEECR-VLSIQSHVIRGYVGNRAATFPLQVLGFEIDAVNSVQFSNHTGY--AHWKGQVLNSDELQELYEGLRLNNMN-KYDYVLTGYTRDKSFLAMVVDIVQELKQQNPRLVYVCDPVLGDKWDGEGSMYVPEDLLPVYKEKVVP---LADIITPNQFEAELLSGRKIHSQEEALRVMDMLHSMGPDTVVITSSDLPSPQGSNYLIVLGSQRRRNPAGSVVMERIRMDIRKVDAVFVGTGDLFAAMLLAWTHKHPN----NLKVACEKTVSTLHHVLQRTIQCAKAQAGEGVRPSP------MQLELRMVQSKRDIEDPEIVVQATVL----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "B0S7H1-1", "uniprot_id": "B0S7H1_DANRE", "id": "B0S7H1-1", "name": "Pyridoxal kinase", "aln": "------MDCR-VLSVQSHVVRGYVGNKSATFPLQVLGFEVDTINSVQFSNHTGY--EHWKGQVLTADELNVLYEGIKLNDVN-HYDYVLTGYTRDYSFLDMVVDIVQELKRANPSLVYVCDPVLGDN----GAMYVPENLLPIYRDRVVP---AADIITPNQFEAELLSGRKIHSEKDAVEVMNLLHSMGPDTVVITSSDLPSPLGDQYLVALGSQKKVRTDGSMVTQQIRMDIPRVDAVFVGTGDLFAAMLLAWTHHHP-----DLKMACEKTASVLHHVIKRTMTYAHEVAGPNRRPSP------AQLELRMVQSKADIENPAVVVNAVIL----", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "B8A4Q2-1", "uniprot_id": "B8A4Q2_DANRE", "id": "B8A4Q2-1", "name": "Pyridoxal kinase", "aln": "------MECR-VLSIQSHVVRGYVGNKSASFPLQVMGFEVDSINSVQFSNHTGY--AHWKGQVLTADELHVLYEGIKLNNVN-HYDYVLTGYNRDTSFLEMVADIVQELKRANPNLVYVCDPVLGDH----GSMYVPQNLHPVYKNKVVP---VADIITPNQFEAELLTGKNISTEKDAVEVMDLLHKMGPDTVVITSSDLPPRLGDRFLVSLGSQRILMPDGTRTTQRIRIEVPKVDAVFVGTGDLFAAMLLAWTHHYPT----DLKTACEKTFSVMHHVIQRTISYAHEMAGPGRRPSP------SQLELRMVQSKADIEDPAIVMEATVL----", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q7KUC2-1", "uniprot_id": "Q7KUC2_DROME", "id": "Q7KUC2-1", "name": "Pyridoxal kinase", "aln": "MAGATNADIKRVLSIQSHVVHGYVGNKVATYPLQLLGFDVDPLNSVQFSNHTGY--KTFKGPVSNEKELATIFEGLEENELLPLYSHLLTGYIGNPLFLRQVGHILKKLRQANPGLVYVCDPVMGDN----GQLYVPKELLPVYRDEIIP---LADIITPNQFEVELLTEKEVRSEAAVWEAMEWFHQRGIKTVVISSSDLGQP---GVLRAFLSQQ----NGPRLAIDIPKQGGK-DLVFTGTGDLFASLFLAHSHGSK-----DIANVFEKTIASLQAVIKRTV--ASLPNGGNGPVKA------AERELKLVQSKTEIEQPQVLLKAQRLN---", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P39988-1", "uniprot_id": "BUD16_YEAST", "id": "P39988-1", "name": "Putative pyridoxal kinase BUD16", "aln": "--------MPRLLATQSHVVHGYVGNKAATFPLQCLGWDVDCCNSVQFSNHTGYGLDKVFGTITRETDLKELLSGLFDNFSQ-DYQALLSGYLPNKNSVRCMGTYYAKFKEANPEMIWLMDPVMGDE----GQLYVSEDVIPEYRKLALSPKQLVDIITPNQFELEILYGGEIKTKEHLKKALKKLHQT-IPVIIVTSCDCKMFDDKDFIYCVASMEG--------KTPIVYRVPFIDSYFTGVGDLFSALLLDRVYKILSN--PTTTLKFEDQVNNVLNVIQKVLKITRSYASGKMKAKMGSALEMKEMELRLIESRDIYETINIHQTDYIYARL-", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P53727-1", "uniprot_id": "BUD17_YEAST", "id": "P53727-1", "name": "Putative pyridoxal kinase BUD17", "aln": "-MTSTLHTTKKVLSIQSHVIHGYVGNKAATFPLQYRGWDVDVLNTVQFSNHSGY--AHFTGFKCSTEELVDIVEKGLIGSLRIKYDAVLSGYLPNVQALQKVAGIVGQLCEGSENVKWILDPVLGDN----GRLYVDRECVAVYQDILQN--FKIFLATPNQFEMELLVGMSIRTLDDAKQAFKLFHKKYPRVSRIVVTSLELS----EFLSNDTYVVAGFDCSASEEIFFYEIPKINAKFSGSGDLISAMLTDSLLGDRRCTQLSLSASLGQVLWLVTSILQKTYDLNIAERGPQDSTID-------IKDLKLIQCRDILKQDLIPSIGKPKTIKI", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . : * *:::* *:******:** * :* : . . *. :*:** : : : :: . . : :: ***:**. * :** .: . *:. : ****** *:* .: : .:. :* . : . : : : : * * ***::::: . : ::::. . :*::::.: : : ", "identical_positions": 42, "similar_positions": 70, "identity": "12.46%" }, { "cls_id": "homologset.agr.MGI:1351872", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9JHI3-1", "uniprot_id": "SO2B1_RAT", "id": "Q9JHI3-1", "name": "Solute carrier organic anion transporter family member 2B1", "aln": "-------------MPDRSTKATMGAEDIHERKVSMEPRDSHQDAQPRGMFQNIKFFVLCHSILQLAQLMISGYLKSSISTVEKRFGLSSQTSGLLAAFNEVGNISLILFVSYFGSRVHRPRMIGCGAILVAVAGLLMALPHFISEP--------YRYDHSSPD-RSQDFEASLCLPTTMAPASALSNDSCSSRTETKHLTMVGIMFTAQTLLGIGGVPIQPFGISYIDDFAHHSNSPLYLGILFAITMMGPGLAYGLGSLMLRLYVDIDRMPEGGINLTTKDPRWVGAWWLGFLISAGLVVLAASPYFFFPREMPKEKYELHFRQKVLAGGASIGSK-GEELSSQHEP---LKKQAGLPQIAPDLTVVQFIKVFPRVLLRTLRHPIFLLVVLSQVCTSSMVAGTATFLPKFLERQFSITASFANLLLGCLTIPLAIVGIVVGGVLVKRLHLSPMQCSALCLLGSLLCLLLSLPLFFIGCSTHHIAGITQDLGAQPGPSLFPGCSEPCSCQSDDFNPVCDTSAYVEYTTPCHAGCTGR----------------------------------------------------VVQEALDKSQVFYTNCSCVAGNGTISAGSCESACSRLVLPFILLISLGAAVASITHTPSFMLILRGVKKEDKTLAVGMQFMLLRVLAWMPSPVIHGSAIDTTCVHWALTCGRRAVCRYYDHDLLRNRFIGLQFFFKSGSLVCFALVLAILRQQSREASTKATVKSSDLQEL---------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8BXB6-1", "uniprot_id": "SO2B1_MOUSE", "id": "Q8BXB6-1", "name": "Solute carrier organic anion transporter family member 2B1", "aln": "-------------MPDRSTKTTMGTEDMHERKVSVEPQDSHQDAQPRGMFHNIKFFVLCHSLLQLTQLMISGYLKSSISTVEKRFGLSSQISGLLAAFNEVGNVSLILFVSYFGSRVHRPRMIGYGALLVATAGLLMALPHFISEP--------YRYDHSSSDNRSLDFEASLCLPTTMAPASALSNGSCSSHTETKHLTMVGIMFAAQTLLGIGGVPIQPFGISYIDDFAHHSNSPLYIGILFGITTMGPGLAYGLGSLMLRLYVDIDRMPEGGINLTPKDPRWVGAWWLGFLISSGLVVLASSPYFFFPREMPKEKHEFHFRRKVLASAASTASK-GEDLSSQHEP---LKKQAGLAQIAPDLTLVQFVKVFPRVLLRNLRHPIFLLVVLSQVCTSSMVAGMATFLPKFLERQFSITASFANMLLGCLTIPLVIVGIMMGGVLVKRLHLSPVQCSALCLLGSLLCLLFSVPLFFIGCSTHQIAGITQDLGAQPGPSLFPGCSEPCSCQSDDFNPVCDTSAYVEYTTPCHAGCTGR----------------------------------------------------VVQEALGKSQVFYTNCSCVAGNGTVPAGSCESACSRLVLPFIVLFSLGAGLASITHTPSFMLILRGVKKEDKTLAVGMQFMLLRVLAWMPSPVIHGSAIDTTCVHWALTCGRRAVCRYYDHDLLRNRFIGLQFFFKSGSLVCFTLVLAILRQQSREASTRTTVKSSELQQL---------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O94956-1", "uniprot_id": "SO2B1_HUMAN", "id": "O94956-1", "name": "Solute carrier organic anion transporter family member 2B1", "aln": "MGPRIGPAGEVPQVPDKETKATMGTENTPGGKASPDP----QDVRP-SVFHNIKLFVLCHSLLQLAQLMISGYLKSSISTVEKRFGLSSQTSGLLASFNEVGNTALIVFVSYFGSRVHRPRMIGYGAILVALAGLLMTLPHFISEP--------YRYDNTSPEDMPQDFKASLCLPTTSAPASAPSNGNCSSYTETQHLSVVGIMFVAQTLLGVGGVPIQPFGISYIDDFAHNSNSPLYLGILFAVTMMGPGLAFGLGSLMLRLYVDINQMPEGGISLTIKDPRWVGAWWLGFLIAAGAVALAAIPYFFFPKEMPKEKRELQFRRKVLAVTDSPARK-GKDSPSKQSPGESTKKQDGLVQIAPNLTVIQFIKVFPRVLLQTLRHPIFLLVVLSQVCLSSMAAGMATFLPKFLERQFSITASYANLLIGCLSFPSVIVGIVVGGVLVKRLHLGPVGCGALCLLGMLLCLFFSLPLFFIGCSSHQIAGITHQTSAHPGLELSPSCMEACSCPLDGFNPVCDPSTRVEYITPCHAGCSSW----------------------------------------------------VVQDALDNSQVFYTNCSCVVEGNPVLAGSCDSTCSHLVVPFLLLVSLGSALACLTHTPSFMLILRGVKKEDKTLAVGIQFMFLRILAWMPSPVIHGSAIDTTCVHWALSCGRRAVCRYYNNDLLRNRFIGLQFFFKTGSVICFALVLAVLRQQDKEARTKESRSSPAVEQQLLVSGPGKKPEDSRV", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VK84-1", "uniprot_id": "Q9VK84_DROME", "id": "Q9VK84-1", "name": "Solute carrier organic anion transporter family member", "aln": "------------MAEVKRRDPNRPPGHYLCGMANWHP-------PWLQKYATTKMFMGVYGLLGTIQAMSYMYFIVTLTTLEKRFKIPSQTTGIILSGNEISQIMLSLILSYIGGQRNRPRWIAWGIVFCGLSCYILVLPHFIYGAGHEVLQFTKEYQDSLLNGTTGSDHSFQNISSVKTERLCGVDKTEDDCDDLFSYVPLVLIFLSQFVLGVGNTLYYSLGQTYLDDNTKKTNTPLMLAVAMALRMIGPVVGFFFGFISLNTFIDPTKTP----LIDSKDPRWLGAWWLGWVILGTLMCLFSGLIGLFPKQLPKVNASRTNSHLPLALRQTKEELKREENLSLSSRFSSNAALDTIGAAAGANADLPKLKDFPRALMRLLRNKLLIFNILSAVFYILGASGFMTFLTKYMEVQFHKDAQSATIIVGPISIMGMVVGLIGSGMVLSKKKPSVSKVLMWNVIVGGISILGQISYAFLYCPN------TFSMTQAGQLNLTSNCNMNCSCEGISYTPVCHEPTDTTFFSACHAGCRGYNATSKLYEDCSCVVNDPAPKSAAQRLLNLLQPTPEPELDTTTYFDEYLSGVPLLDDNGDFDDQLLSRTRRSTSDSVIRPGICTKNCNWSFWAFSITSMIVSWFGSSGRVGNVLVNYRAVAHEDKSFAQGLALMMISLLALIPGPIIFGRLIDSTCLVWTKTCNGNGNCQLYDQTRFRYSLNFLSCLLTFMGLLFDYLVWYYGRNLDIYGDKEAKEEERANRKDQPITPLLAKKSEQE-", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : ... . . .. .* : . *:*: :.:* * * *: :::*:**** :.** :*:: : **:.: * :::**:*.: :*** *. * :: . : ::.***** . .*:.: : . . .: :.:. : . : . .. : : ::* :* :**:*.. .:* :*:** ::::*:** :.: :.: :** :.: :* : *. ::* : * : *****:******::* . : * : :**:::** : . : ** : :: * . : * : : :* ***.*:: **: :::: :** * .:* ***.*::* ** *. *.:::* ::: :**:: .*:::.: : . :: :.:: .:. *: *.. * . .* ..* *** .:.***. .: . : :.***** . :::: . .: : :. . .. : .* * . *. . .* : : : ... :. ..:: *.* :***::* *: :*:: :** :*.*:*.* **:**: *: :*. .. *: *:: :* : *. ::. .:: ** *: . . .. . .. .: ", "identical_positions": 142, "similar_positions": 254, "identity": "18.32%" }, { "cls_id": "homologset.agr.MGI:1351891", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9VK84-1", "uniprot_id": "Q9VK84_DROME", "id": "Q9VK84-1", "name": "Solute carrier organic anion transporter family member", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------MAEVKRRDPNRPPGHYLCGMANWHPPWLQKYATTKMFMGVYGLLGTIQAMSYMYFIVTLTTLEKRFKIPSQTTGIILSGNEISQIMLSLILSYIGGQRNRPRWIAWGIVFCGLSCYILVLPHFIYGAGHEV--------LQFTKEYQDSLLNGTTGSDHSFQNISSVKTERLCGVDKTED-----DCDDLFSYVPLVLIFLSQFVL-GVGNTLYYSLGQTYLDDNTKKTNTPLMLAVAMALRMIGPVVGFFFGFISLNTFIDP----TKTPLIDSKDPRWLGAWWLGWVILGTLMCLFSGLIGLFPKQLPKVNASRTNSHLPLALRQTKEELKREENLSLSSRFSSNAALDTIGAAAGANADLPKLKDFPRALMRLLRNKLLIFNILSAVFYILGASGFMTFLTKYMEVQFHKDAQSATIIVGPISIMGMVVGLIGSGMVLSKKKPSVSKVLMWNVIVGGISILGQISYAFLYCPNTFSMTQAGQLN-----------LTSNCNMNCSCEGISYTPVCHEPTDTTFFSACHAGCRG---YNATS-KLYEDCSCVVNDPAPKSAAQRLLNLLQPTPEPELDTTTYFDEYLSGVPLLDDNGDFDDQLLSRTRRSTSDSVIRPGICTKNCNWSFWAFSITSMIVSWFGSSGRVGNVLVNYRAVAHEDKSFAQGLALMMISLLALIPGPIIFGRLIDSTCLVWT-KTCNGNGNCQLYDQTRFRYSLNFLSCLLTFMGLLFDYLVWYYGRNLDIYGDKE----AKEEERANRKDQPITPLLAKKSEQE----------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9W270-1", "uniprot_id": "Q9W270_DROME", "id": "Q9W270-1", "name": "Solute carrier organic anion transporter family member", "aln": "--------------------------------------------------------------------------------------------------------------------------MASEEIEASKFLKDKEAGINVADDEKRLNSSDTTCGFSIFRGPALQRFATAHMFVIVYGIASCFLAMAFTYFTGTITTMEKRFNIPTKISGLITVGNDISTVFSSAFLSYYASRGHRPRWVALGLIIIAIFCLLMLTPHIFYGPGEEA--------LRLTEEYGMSESFGAS--------LNITEKNDSLCHEKNSN-----CLERAGDYTPIVLFFIAQFIG-GIGCSLFYAPGLSYMDDNSASSKTPAMLSWSSFLRMLGPAMGFSMVSLCLRLYIDP----FKKPLITTNDPRWMGAWWIGWILLTFILTISAVFVGMFPKEMPRAKARRLKADG-------------EEDIPLAGRS---------------------FQDMLDSLKRLASNKVYVYNMLASILYLFGYMPYWIFTPKYIEIQYRQSASTSTMATGTWALGFSAAGILISGYVISKYKPSARAMAAWNFVVDYLTVAGMLCYVLVGCDESDRANSLSIVP-----------TGDSCSASCVCEYVYYAPVCSP-ENITFISACHAGCTDKAINELGK-TIYTGCRCMGNVSSIIS------------------------------------------LSNVTSLASQSQIAMDGACPVDCNKQFLIFLAVMCFLKFVGATGRSSNLLLALRCVPSKDKTFSLGFGSMVYSVLAFIPSPIVFGWMLDSYCLVWG-KTCSSKGNCWIYDTKSLRYTMNLVCASLIFLGSFWNIGVWYHAKDMKVFDEDEKTVQAKQSDDIELKEKPNDVVTKKK--------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P46720-1", "uniprot_id": "SO1A1_RAT", "id": "P46720-1", "name": "Solute carrier organic anion transporter family member 1A1", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------MEETEKKIATQ------------EGRLFSKMKVFLLSLTCACLTKSLSGVYMNSMLTQIERQFDISTSVAGLINGSFEIGNLFFIVFVSYFGTKLHRPVVIGIGCVIMGLGCLLMSLPHFFMG------------------RYEYETTISPTGNLSSNSFLCMENRTQTLKPTQDPA-----ECVKEMKSLMWICVMVGNIIR-GIGETPIVPLGISYIEDFAKSENSPLYIGILEMGKVAGPIFGLLLGSYCAQIYVDIGSVNTDDLTITPSDTRWVGAWWIGFLVCAGVNILTSIPFFFLPKALPKKGQQENVAVTKDG--------KVEKYGGQAREEN-----------------LGITKDFLTFMKRLFCNPIYMLFILTSVLQVNGFINKFTFLPKYLEQQYGKSTAEAIFLIGVYSLPPICLGYLIGGFIMKKFKITVKKAAYLAFCLSVFEYLLFLCHFMLTCDNAAVAGLTTSYKGVQHQLHVESKVLADCNTRCSCSTNTWDPVCGD-NGVAYMSACLAGCKKF-VGTGTN-MVFQDCSCIQSL------------------------------------------------------GNSSAVLGLCKKGPECANRLQYFLILTIIISFIYSLTAIPGYMVFLRCVKSEEKSLGVGLHTFCIRVFAGIPAPVYFGALIDRTCLHWGTLKCGQRGACRMYDINSFRHIYLGLPIALRGSSYLPAFFILILMRKFQFPGDIDSSATDHTEMMLGEKESEHTDVHGSPQVENDGELKTKL--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9QXZ6-1", "uniprot_id": "SO1A1_MOUSE", "id": "Q9QXZ6-1", "name": "Solute carrier organic anion transporter family member 1A1", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------MEETEKKVATQ------------EGRFFSKMKVFLMSLTCAYLAKSLSGVYMNSMLTQIERQFGIPTSVVGFITGSFEIGNLLLIVFVSYFGRKLHRPIIIGVGCVVMGLGCFLMASPHFLMG------------------RYKYETTISPTSNLSSNSFLCIENRTQTLKPTQDPT-----ECVKEIKSLMWIYVLIGNTMR-GIGETPIMPLGISYIEDFAKSENSPLYIGILEMGKIVGPIIGLLLGSFFARVYVDIGSVNTDDLTITPTDTRWVGAWWIGFLVCAGVNILTSIPFFFFPKTLPKKELQDNVDVTKYE--------KVEKHRERAKKEN-----------------LGITKDFLPFMKSLCCNPIYMLFSLTSVLQINGFASTFTFLPKYLEQQYGKSTSEAVFLIGVYSLPPVCLGYLISGFIMKKFKITVKKAAYIAFGLSLSEYFIFLCNYLLTCDNFPVAGLTTSYKGVQHPLYGEKNVLADCNTRCSCLTDTWDPVCGD-NGLAYMSACLAGCEKS-VGTGTN-MVFQNCSCIGSS------------------------------------------------------GNSSAVLGLCKKGPECDNKLQYFLIKSVFSSFIFSLAAIPGYMVLLRCVKSEEKSIGVGLHAFFIRLLAGIPAPVYFGALIDRTCLHWGTLKCGQPGACRMYDINRFRHIYLGLPAAVRGSSFLPAVFILILMRKFHFPGDIHSPDTELAEMKLTEKESECTDVCRSPKVENDGELKTKL--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P46721-1", "uniprot_id": "SO1A2_HUMAN", "id": "P46721-1", "name": "Solute carrier organic anion transporter family member 1A2", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------MGETEKRIETH------------RIRCLSKLKMFLLAITCAFVSKTLSGSYMNSMLTQIERQFNIPTSLVGFINGSFEIGNLLLIIFVSYFGTKLHRPIMIGIGCVVMGLGCFLKSLPHFLMN------------------QYEYESTVSVSGNLSSNSFLCMENGTQILRPTQDPS-----ECTKEVKSLMWVYVLVGNIVR-GMGETPILPLGISYIEDFAKFENSPLYIGLVETGAIIGPLIGLLLASFCANVYVDTGFVNTDDLIITPTDTRWVGAWWFGFLICAGVNVLTAIPFFFLPNTLPKEGLETNADIIKNE--------NEDKQKEEVKKEK-----------------YGITKDFLPFMKSLSCNPIYMLFILVSVIQFNAFVNMISFMPKYLEQQYGISSSDAIFLMGIYNLPPICIGYIIGGLIMKKFKITVKQAAHIGCWLSLLEYLLYFLSFLMTCENSSVVGINTSYEGIPQDLYVENDIFADCNVDCNCPSKIWDPVCGN-NGLSYLSACLAGCETS-IGTGIN-MVFQNCSCIQTS------------------------------------------------------GNSSAVLGLCDKGPDCSLMLQYFLILSAMSSFIYSLAAIPGYMVLLRCMKSEEKSLGVGLHTFCTRVFAGIPAPIYFGALMDSTCLHWGTLKCGESGACRIYDSTTFRYIYLGLPAALRGSSFVPALIILILLRKCHLPGENASSGTELIETKVKGKENECKDIYQKSTVLKDDELKTKL--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0ACD6B7C1-1", "uniprot_id": "A0ACD6B7C1_DANRE", "id": "A0ACD6B7C1-1", "name": "Solute carrier organic anion transporter family member", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------MSEPTIEDNGKPTSQQELCS----PEAPEEPRCSSLKIFIGALSFAYFSKTLCGTYMKSAITQIERRFDLSSSAVGLVDGSFEMGNLLFVAVVSHFGARLHRPRLIGMGCFLMAIGSALTGLPHVFMG------------------RYKFDTAVQGFANETVVIAPCQYPTNPSEHSIQHIDNTTGTDCVKDPGSSMWIYVFLGNALR-GIGETPVTPLGISYIDDFAKAENSAFYISCLQTIMLLGPMFGFLLGSMCAKLYVDIGFVSVDSVSITPQDARWVGAWWLGFFVSSAFLVLSGVPFWFLPRSLPKQG-EEEKEIYNTD--------DANKEHSVLQTTHTMTL-------------ADIAKGFLPSLKRLLCTPAYFLLLCGIVLKFNSFIGLLTFKAKYMEQQFGQSASRANFLIGVLILPVVAVGIFLGGLLMKKYKLSVVAGAQLSFITSFTAFLLLLLHFGTKCDNVPVAGLTVSYNGTPYMPSDQRSLESQCNQDCSCSTSEWDPVCSD-SGITYMSPCLAGCTAS-TGQGKN-TVFHNCSCVLSPS--------------------------------------------------PAEGGRSVSLGQCPQGSACARSFTSYMAVSVLSSFINSLGTTPGYMIIIRCIAPELKSLALGIQTLVMRTLGGIPAPIYFGALIDTTCLKWGLKKCGGRGACRIYDSNMYRVIFLSLTTALSGCSYFFIIAVIVLLRRQFIKEEVK--ALQQMAGKQNEIELRSPEMQNPDGTKTDERDKNNTEG", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VVH9-1", "uniprot_id": "SO74D_DROME", "id": "Q9VVH9-1", "name": "Solute carrier organic anion transporter family member 74D", "aln": "MTKSNGDVEAAAQVQSLGGKPSNGHGQLNGNGYHQNGGRRDSSQAFTPLLSQHNNGTTNGEVTTPPPSTVLYESTPSNNNEWKAPEDLGHLKNGLGNILSSNNNGTGNGHSLSEKYAHEQAPLTGGYKLPPRSSESEESDFDSDLNGGSSAESSSSCGLFGCRPRWARRFASTHVFMVVFLLAYILQGMYMTYFVSVITTIEKLFQIKSKTTGILLSASEMGQICTAMLLTYFAGRGHRPRWIACGMVLFSIAAFSCALPHFIFGEQLMHSSVILQQTQVSPPNNSFSSHWLNASSEQVNPNLCILGGNQTHSGSECNEERQLEQASHSKITVIVLCIFFGSLLSSGIGQTAVATLGIPYIDDNVGSKQSPMYMAVTIGMRILGPASGFIFGSFCTRWYVNFS-----NPGFDATDPRWIGAWWLGPVAIGSLMLLASIAMFSFPKQLRGKQKPPGQTATPAAP------------VEPEEKPK--------------------LKDFPKTVRRQLSNDILMFRTASCVFHLLPIAGLYTFLPKYLETQFRLATYDANMIAAFCGILVMGIGIVISGLFILKRKPTARGVAAWIAFTALVYSAGMIILMFIGCSMNDFAGYKPSDGNSP----ALIEPTCSAALNCTCDKENFAPICAD--GKMYISACHAGCSSSSLRPSDNRTLYSDCACIPDAP----------------------------------------------------------EAVNGYCDNNCKN-FIYFILIFAICVFMHSTSEVGSMLLVMRCTHPKDKAMAMGVIQSAIGLFGNVPCPIIYGAVVDSACLIWK-SVCGKHGACSLYDADTFRQYFLGITAGIMFLAFLMDLVVWRKAHRIDIAPEDPQEGGPASNGRTLEVSESKQPITPAPDTTV----------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :. ::*: : *: :* :*: * : :. *:: . ::. : .::: . : :** :. * .. .: . **.: . . . : : .:... : *:* : . * .*::* ::. :. : ** *: : . ::: : . *.**:****:* . . : . . :*. : :.: : . . :: . * .**:* *: : : : . : * . .* .: * * :. : * .. * * : *:* . ::*.* *** . :: .* *: * : : : :. : . :: *. : *::. *. :. :* *: :* ::* ** * *. * * :** * : : . . : : . : . : ", "identical_positions": 66, "similar_positions": 149, "identity": "7.08%" }, { "cls_id": "homologset.agr.MGI:1351896", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9VK84-1", "uniprot_id": "Q9VK84_DROME", "id": "Q9VK84-1", "name": "Solute carrier organic anion transporter family member", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------MAEVKRRDPNRPPGHYLCGMANWHPPWLQKYATTKMFMGVYGLLGTIQAMSYMYFIVTLTTLEKRFKIPSQTTGIILSGNEISQIMLSLILSYIGGQRNRPRWIAWGIVFCGLSCYILVLPHFIYGAGHEVLQFTKEYQDSLLNGTTGSDHSF-------------QNISSVKTERLCGVDKTEDDCDDLFSYVPLVLIFLSQFVL-GVGNTLYYSLGQTYLDDNTKKTNTPLMLAVAMALRMIGPVVGFFFGFISLNTFIDP----TKTPLIDSKDPRWLGAWWLGWVILGTLMCLFSGLIGLFPKQLPKVNASRTNSHLPLALRQTKEELKREENLSLSSRFSSNAALDTIGAAAGANADLPKLKDFPRALMRLLRNKLLIFNILSAVFYILGASGFMTFLTKYMEVQFHKDAQSATIIVGPISIMGMVVGLIGSGMVLSKKKPSVSKVLMWNVIVGGISILGQISYAFLYCPNTFSMTQAGQLN-----------LTSNCNMNCSCEGISYTPVCHEPTDTTFFSACHAGCRG---YNATS-KLYEDCSCVVNDPAPKSAAQRLLNLLQPTPEPELDTTTYFDEYLSGVPLLDDNGDFDDQLLSRTRRSTSDSVIRPGICTKNCNWSFWAFSITSMIVSWFGSSGRVGNVLVNYRAVAHEDKSFAQGLALMMISLLALIPGPIIFGRLIDSTCLVWT-KTCNGNGNCQLYDQTRFRYSLNFLSCLLTFMGLLFDYLVWYYGRNLDIYGDKE-----AKEEERANRKDQPITPLLAKKSEQE--------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9W270-1", "uniprot_id": "Q9W270_DROME", "id": "Q9W270-1", "name": "Solute carrier organic anion transporter family member", "aln": "--------------------------------------------------------------------------------------------------------------------------MASEEIEASKFLKDKEAGINVADDEKRLNSSDTTCGFSIFRGPALQRFATAHMFVIVYGIASCFLAMAFTYFTGTITTMEKRFNIPTKISGLITVGNDISTVFSSAFLSYYASRGHRPRWVALGLIIIAIFCLLMLTPHIFYGPGEEALRLTEEYGMSESFGAS---------------------LNITEKNDSLCHEKNSNCLERAGDYTPIVLFFIAQFIG-GIGCSLFYAPGLSYMDDNSASSKTPAMLSWSSFLRMLGPAMGFSMVSLCLRLYIDP----FKKPLITTNDPRWMGAWWIGWILLTFILTISAVFVGMFPKEMPRAKARRLKADG-------------EEDIPLAGRS---------------------FQDMLDSLKRLASNKVYVYNMLASILYLFGYMPYWIFTPKYIEIQYRQSASTSTMATGTWALGFSAAGILISGYVISKYKPSARAMAAWNFVVDYLTVAGMLCYVLVGCDESDRANSLSIVP-----------TGDSCSASCVCEYVYYAPVCSP-ENITFISACHAGCTDKAINELGK-TIYTGCRCMGNVSSIIS------------------------------------------LSNVTSLASQSQIAMDGACPVDCNKQFLIFLAVMCFLKFVGATGRSSNLLLALRCVPSKDKTFSLGFGSMVYSVLAFIPSPIVFGWMLDSYCLVWG-KTCSSKGNCWIYDTKSLRYTMNLVCASLIFLGSFWNIGVWYHAKDMKVFDEDEK-TVQAKQSDDIELKEKPNDVVTKKK------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "O35913-1", "uniprot_id": "SO1A4_RAT", "id": "O35913-1", "name": "Solute carrier organic anion transporter family member 1A4", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------MGK----------SEKRVATHGVR---CFAKIKMFLLALTCAYVSKSLSGTYMNSMLTQIERQFGIPTSIVGLINGSFEIGNLLLIIFVSYFGTKLHRPIMIGVGCAVMGLGCFLISLPHFLMGQYEYET-ILPTSNVSSNSFFCV-----------------------ENRSQTLNPTQDPSECVKEMKSLMWIYVLVGNIIR-GIGETPIMPLGISYIEDFAKSENSPLYIGILETGMTIGPLIGLLLASSCANIYVDIESVNTDDLTITPTDTRWVGAWWIGFLVCAGVNILTSFPFFFFPKTLPKEGLQEN-VDGTEN--------AKEKKHRKKAKEEK----------------RGITKDFFVFMKSLSCNPIYMLFILISVLQFNAFINSFTFMPKYLEQQYGKSTAEVVFLMGLYMLPPICLGYLIGGLIMKKFKVTVKKAAHLAFWLCLSEYLLSFLSYVMTCDNFPVAGLTTSYEGVQHQLYVENKVLADCNTRCNCSTNTWDPVCGD-NGLAYMSACLAGCEKS-VGTGTN-MVFQNCSCIQSS------------------------------------------------------GNSSAVLGLCNKGPDCANKLQYFLIIAIFGCFIYSLAGIPGYMVLLRCIKSEEKSLGVGLHAFCIRILAGIPAPIYFGALIDRTCLHWGTLKCGEPGACRMYDINSFRRLYLGLPAALRGASFVPAFFILRLTRTFQFPGDIES-SKTDHAEMKLTLKESECTEVLRSKVTED--------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9EP96-1", "uniprot_id": "SO1A4_MOUSE", "id": "Q9EP96-1", "name": "Solute carrier organic anion transporter family member 1A4", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------MGK----------SEKEVATHGVR---CFSKIKAFLLALTCAYVSKSLSGTYMNSMLTQIERQFGIPTSVVGLINGSFEIGNLLLIIFVSYFGTKLHRPIMIGVGCAVMGLGCFLISIPHFLMGRYEYETTILPTSNLSSNSFVCT-----------------------ENRTQTLKPTQDPTECVKEMKSLMWIYVLVGNIIR-GMGETPIMPLGISYIEDFAKSENSPLYIGILETGMTIGPLIGLLLGSSCANIYVDTGSVNTDDLTITPTDTRWVGAWWIGFLVCAGVNILTSIPFFFFPKTLLKEGLQDN-GDGTEN--------AKEEKHREKIKEEN----------------RGITKDFFLFMKSLSCNPIYMIFILISVIQVNAFINSFTFMPKYLEQQYGKSTAEIVFLMGLYMLPPICLGYLIGGLIMKKFKITVKKAAYIGFWLSLTEYLLSFVSYIMTCDNFPVAGLTTSYEGVQHPLYVENNVLADCNTKCSCLTNTWDPVCGD-NGLSYMSACLAGCEKS-VGTGTN-MVFQNCSCIQSS------------------------------------------------------GNASAVLGLCDKGPECANKLQYFLIISIIGCFIFSLGAIPGYMVLLRCMKSEEKSLGVGLHTFCMRILGGIPAPIYFGALIDRTCLHWGTLKCGEPGACRMYDINSFRRIYLGLPAALRGASFLPALFILILMRKFQFPGDIDS-SDTDPAEMKLTAKESKCTNVHRSPTMQNDGERKTKL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P46721-1", "uniprot_id": "SO1A2_HUMAN", "id": "P46721-1", "name": "Solute carrier organic anion transporter family member 1A2", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------MGE----------TEKRIETHRIR---CLSKLKMFLLAITCAFVSKTLSGSYMNSMLTQIERQFNIPTSLVGFINGSFEIGNLLLIIFVSYFGTKLHRPIMIGIGCVVMGLGCFLKSLPHFLMNQYEYESTVSVSGNLSSNSFLCM-----------------------ENGTQILRPTQDPSECTKEVKSLMWVYVLVGNIVR-GMGETPILPLGISYIEDFAKFENSPLYIGLVETGAIIGPLIGLLLASFCANVYVDTGFVNTDDLIITPTDTRWVGAWWFGFLICAGVNVLTAIPFFFLPNTLPKEGLETN-ADIIKN--------ENEDKQKEEVKKEK----------------YGITKDFLPFMKSLSCNPIYMLFILVSVIQFNAFVNMISFMPKYLEQQYGISSSDAIFLMGIYNLPPICIGYIIGGLIMKKFKITVKQAAHIGCWLSLLEYLLYFLSFLMTCENSSVVGINTSYEGIPQDLYVENDIFADCNVDCNCPSKIWDPVCGN-NGLSYLSACLAGCETS-IGTGIN-MVFQNCSCIQTS------------------------------------------------------GNSSAVLGLCDKGPDCSLMLQYFLILSAMSSFIYSLAAIPGYMVLLRCMKSEEKSLGVGLHTFCTRVFAGIPAPIYFGALMDSTCLHWGTLKCGESGACRIYDSTTFRYIYLGLPAALRGSSFVPALIILILLRKCHLPGENAS-SGTELIETKVKGKENECKDIYQKSTVLKDDELKTKL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0ACD6B7C1-1", "uniprot_id": "A0ACD6B7C1_DANRE", "id": "A0ACD6B7C1-1", "name": "Solute carrier organic anion transporter family member", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------MSEPTIEDNGKPTSQQELCSPEAPEEPRCSSLKIFIGALSFAYFSKTLCGTYMKSAITQIERRFDLSSSAVGLVDGSFEMGNLLFVAVVSHFGARLHRPRLIGMGCFLMAIGSALTGLPHVFMGRYKFDTAVQGFANETVVIAPCQY-----------------PTNPSEHSIQHIDNTTG-TDCVKDPGSSMWIYVFLGNALR-GIGETPVTPLGISYIDDFAKAENSAFYISCLQTIMLLGPMFGFLLGSMCAKLYVDIGFVSVDSVSITPQDARWVGAWWLGFFVSSAFLVLSGVPFWFLPRSLPKQGEEEKEIYNTDD--------ANKEHSVLQTTHTMTL--------------ADIAKGFLPSLKRLLCTPAYFLLLCGIVLKFNSFIGLLTFKAKYMEQQFGQSASRANFLIGVLILPVVAVGIFLGGLLMKKYKLSVVAGAQLSFITSFTAFLLLLLHFGTKCDNVPVAGLTVSYNGTPYMPSDQRSLESQCNQDCSCSTSEWDPVCSD-SGITYMSPCLAGCTAS-TGQGKN-TVFHNCSCVLSPS--------------------------------------------------PAEGGRSVSLGQCPQGSACARSFTSYMAVSVLSSFINSLGTTPGYMIIIRCIAPELKSLALGIQTLVMRTLGGIPAPIYFGALIDTTCLKWGLKKCGGRGACRIYDSNMYRVIFLSLTTALSGCSYFFIIAVIVLLRRQFIKEEVKALQQMAGKQNEIELRSPEMQNPDGTKTDERDKNNTEG-", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VVH9-1", "uniprot_id": "SO74D_DROME", "id": "Q9VVH9-1", "name": "Solute carrier organic anion transporter family member 74D", "aln": "MTKSNGDVEAAAQVQSLGGKPSNGHGQLNGNGYHQNGGRRDSSQAFTPLLSQHNNGTTNGEVTTPPPSTVLYESTPSNNNEWKAPEDLGHLKNGLGNILSSNNNGTGNGHSLSEKYAHEQAPLTGGYKLPPRSSESEESDFDSDLNGGSSAESSSSCGLFGCRPRWARRFASTHVFMVVFLLAYILQGMYMTYFVSVITTIEKLFQIKSKTTGILLSASEMGQICTAMLLTYFAGRGHRPRWIACGMVLFSIAAFSCALPHFIFGEQLMHSSVILQQTQVSPPNNSFSSHWLNASSEQVNPNLCILGGNQTHSGSECNEERQLEQASHSKITVIVLCIFFGSLLSSGIGQTAVATLGIPYIDDNVGSKQSPMYMAVTIGMRILGPASGFIFGSFCTRWYVNFS-----NPGFDATDPRWIGAWWLGPVAIGSLMLLASIAMFSFPKQLRGKQKPPGQTATPAAP-------VEPEEKPK-------------------------LKDFPKTVRRQLSNDILMFRTASCVFHLLPIAGLYTFLPKYLETQFRLATYDANMIAAFCGILVMGIGIVISGLFILKRKPTARGVAAWIAFTALVYSAGMIILMFIGCSMNDFAGYKPSDGNSP----ALIEPTCSAALNCTCDKENFAPICAD--GKMYISACHAGCSSSSLRPSDNRTLYSDCACIPDAP----------------------------------------------------------EAVNGYCDNNCKN-FIYFILIFAICVFMHSTSEVGSMLLVMRCTHPKDKAMAMGVIQSAIGLFGNVPCPIIYGAVVDSACLIWK-SVCGKHGACSLYDADTFRQYFLGITAGIMFLAFLMDLVVWRKAHRIDIAPEDPQEGGPASNGRTLEVSESKQPITPAPDTTV---------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . :. : *: . : *: :* :*: * : :. *:: . ::. : .::: . : :** :. * . .: . **.: . . . : .:... : *:* : . * .*::* ::. :. :** *: : . . ::: : . *.**:****:* . . : . . :*. : .. :.: : . . :: . * .**:* *: : : . : * . .* .: * * :. : * .. * * : *:* . ::*.* *** . :: .* *: * : : : :. : . . :: *. : *::. *. :. :* ** :* ::* ** * *. * * :** * : : . . : : . : . ", "identical_positions": 67, "similar_positions": 149, "identity": "7.2%" }, { "cls_id": "homologset.agr.MGI:1351899", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9NPD5-1", "uniprot_id": "SO1B3_HUMAN", "id": "Q9NPD5-1", "name": "Solute carrier organic anion transporter family member 1B3", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------MDQHQHLNKTAESASSEKKKTRRCNGFKMFLAALSFSYIAKALGGIIMKISITQIERRFDISSSLAGLIDGSFEIGNLLVIVFVSYFGSKLHRPKLIGIGCLLMGTGSILTSLPHFFMG----YYRYSKET-HINPSENSTSSLSTCLINQTLSF------------NGTSPEIVEKD-CVKESGSHMWIYVFMGNMLR-GIGETPIVPLGISYIDDFAKEGHSSLYLGSLNAIGMIGPVIGFALGSLFAKMYVDIGYVDLSTIRITPKDSRWVGAWWLGFLVSGLFSIISSIPFFFLPKNPNK---PQKERKISLS----LHVLKTNDDRNQTANLTNQGKNVT-----------KNVTGFFQSLKSILTNPLYVIFLLLTLLQVSSFIGSFTYVFKYMEQQYGQSASHANFLLGIITIPTVATGMFLGGFIIKKFKLSLVGIAKFSFLTSMISFLFQLLYFPLICESKSVAGLTLTYDGNNSVASHVDVPLSYCNSECNCDESQWEPVCGN-NGITYLSPCLAGCKSSSGIKKH--TVFYNCSCVE----------------------------------------------------VTGLQNRNYSAHLGECPRDNTCTRKFFIYVAIQVINSLFSATGGTTFILLTVKIVQPELKALAMGFQSMVIRTLGGILAPIYFGALIDKTCMKWSTNSCGAQGACRIYNSVFFGRVYLGLSIALRFPALVLYIVFIFAMKKKFQGKDTKASDNERKVMDEANLEFLN-NGEHFVPSAGTDSKTCNLDMQDNAAAN", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9Y6L6-1", "uniprot_id": "SO1B1_HUMAN", "id": "Q9Y6L6-1", "name": "Solute carrier organic anion transporter family member 1B1", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------MDQNQHLNKTAEAQPSENKKTRYCNGLKMFLAALSLSFIAKTLGAIIMKSSIIHIERRFEISSSLVGFIDGSFEIGNLLVIVFVSYFGSKLHRPKLIGIGCFIMGIGGVLTALPHFFMG----YYRYSKET-NINSSENSTSTLSTCLINQILSL------------NRASPEIVGKG-CLKESGSYMWIYVFMGNMLR-GIGETPIVPLGLSYIDDFAKEGHSSLYLGILNAIAMIGPIIGFTLGSLFSKMYVDIGYVDLSTIRITPTDSRWVGAWWLNFLVSGLFSIISSIPFFFLPQTPNK---PQKERKASLS----LHVLETNDEKDQTANLTNQGKNIT-----------KNVTGFFQSFKSILTNPLYVMFVLLTLLQVSSYIGAFTYVFKYVEQQYGQPSSKANILLGVITIPIFASGMFLGGYIIKKFKLNTVGIAKFSCFTAVMSLSFYLLYFFILCENKSVAGLTMTYDGNNPVTSHRDVPLSYCNSDCNCDESQWEPVCGN-NGITYISPCLAGCKSSSGNKKP--IVFYNCSCLE----------------------------------------------------VTGLQNRNYSAHLGECPRDDACTRKFYFFVAIQVLNLFFSALGGTSHVMLIVKIVQPELKSLALGFHSMVIRALGGILAPIYFGALIDTTCIKWSTNNCGTRGSCRTYNSTSFSRVYLGLSSMLRVSSLVLYIILIYAMKKKYQEKDINASEN-GSVMDEANLESLN-KNKHFVPSAGADSETHC----------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "G3V0H7-1", "uniprot_id": "SO1B7_HUMAN", "id": "G3V0H7-1", "name": "Putative solute carrier organic anion transporter family member 1B7", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MKISTTQIERRFEISSSLVGLIDGSFEIGNLFVIVFVSYFGSKLHRPKLIGIGCFLMGTGSILMALPHFFMG----YYRYSKET-NIDPSENSTSNLPNCLINQMLSL------------NRTPSEIIERG-CVKESGSHMWIYVFMGNMLR-GIGETPIVPLGISYIDDFAKEGHSSLYLGTVNVMGMTGLVFAFMLGSLFAKMYVDIGYVDLSTIRITPKDSRWVGAWWLGFLVSGIVSIISSIPFFFLPLNPNK---PQKERKVSLF----LHVLKTNDKRNQIANLTNRRKYIT-----------KNVTGFFQSLKSILTNPLYVIFVIFTLLHMSSYIASLTYIIKMVEQQYGWSASKTNFLLGVLALPAVAIGMFSGGYIIKKFKLSLVGLAKLAFCSATVHLLSQVLYFFLICESKSVAGLTLTYDGNSPVRSHVDVPLSYCNSECNCDESQWEPVCGN-NGITYLSPCLAGCKSSSGNKEP--IVFYNCSCVE----------------------------------------------------VIGLQNKNYSAHLGECPRDDACTRKSYVYFVIQVLDAFLCAVGLTSYSVLVIRIVQPELKALAIGFHSMIMRSLGGILVPIYFGALIDTTCMKWSTNSCGARGACRIYNSTYLGRAFFGLKVALIFPVLVLLTVFIFVVRKKSHGKDTKVLENERQVMDEANLEFLN-DSEHFVPSAEEQ---------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9QZX8-2", "uniprot_id": "SO1B2_RAT", "id": "Q9QZX8-2", "name": "Solute carrier organic anion transporter family member 1B2", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------MDHTQQSRKAAEAQPSRSKQTRFCDGFKLFLAALSFSYICKALGGVVMKSSITQIERRFDIPSSISGLIDGGFEIGNLLVIVFVSYFGSKLHRPKLIGIGCFIMGIGSILTALPHFFMG----YYKYAKEN-DIGSLGNST---LTCFINQMTSP------------TGPSPEIVEKG-CEKGLKSHMWIYVLMGNMLR-GIGETPIVPLGISYLDDFAKEGHTSMHLGTLHTIAMIGPILGFIMSSVFAKIYVDVGYVDLNSVRITPNDARWVGAWWLSFIVNGLLCITSSIPFFFLPKIPKR---SQEERKNSVS----LHAPKTDEEKKHMTNLTKQEEQDP-----------SNMTGFLRSLRSILTNEIYVIFLILTLLQVSGFIGSFTYLFKFIEQQFGRTASQANFLLGIITIPTMATAMFLGGYIVKKFKLTSVGIAKFVFFTSSVAYAFQFLYFPLLCENKPFAGLTLTYDGMNPVDSHIDVPLSYCNSDCSCDKNQWEPICGE-NGVTYISPCLAGCKSFRGDKKPNNTEFYDCSCIS----------------------------------------------------NS----GNNSAHLGECPRY-KCKTNYYFYIILQVTVSFFTAMGSPSLILILMKSVQPELKSLAMGFHSLIIRALGGILAPIYYGAFIDRTCIKWSVTSCGKRGACRLYNSRLFGFSYLGLNLALKTPPLFLYVVLIYFTKRKYKRNDNKTLENGRQFTDEGNPDSVNKNGYYCVPYDEQSNETPL----------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9JJL3-1", "uniprot_id": "SO1B2_MOUSE", "id": "Q9JJL3-1", "name": "Solute carrier organic anion transporter family member 1B2", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------MDQTQHPSKA--AQPLRSEKTRHCDGFRIFLAALSFSYICKALGGVIMKSSITQIERRFDIPSSISGLIDGGFEIGNLLVIVFVSYFGSKLHRPKLIGTGCFIMGIGSILTALPHFFMG----YYRYATEN-DISSLHNST---LTCLVNQTTSL------------TGTSPEIMEKG-CEKGSNSYTWIYVLMGNMLR-GIGETPIVPLGVSYIDDFAKEGNSSMYLGTLHTIAMIGPILGFIMSSVFAKLYVDVGYVDLRSVRITPQDARWVGAWWLGFIVNGLLCIICSIPFFFLPKIPKR---SQKERKNSAS----LHVLKTDEDKNPVTNPTTQEKQAP-----------ANLTGFLWSLRSILTNEQYVIFLILTLLQISSFIGSFTYLFKFIEQQFGQTASQANFLLGVITIPTMASGMFLGGYLIKRLKLTLLGITKFVFFTTTMAYVFYLSYFLLICENKAFAGLTLTYDGMNPVDSHIDVPLSYCNSDCICDKNQWEPVCGE-NGVTYISPCLAGCKSFRGDKKLMNIEFYDCSCVS----------------------------------------------------GSGFQKGNHSARLGECPRD-KCKTKYYFYITFQVIISFFTALGSTSLMLILIRSVQPELKSLGMGFHSLVVRTLGGILAPVYYGALIDRTCMKWSVTSCGARGACRLYNSRLFGMIYVGLSIALKTPILLLYVALIYVMKRKMKRNDNKILENGRKFTDEGNPEPVNNNGYSCVPSDEKNSETPL----------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8M9PU70-1", "uniprot_id": "A0A8M9PU70_DANRE", "id": "A0A8M9PU70-1", "name": "Solute carrier organic anion transporter family member", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------MSTEKKKEPCCSKLKMFLAAMCFVFFAKAFQGSYMKSSVTQIERRFDVPSSLIGFIDGSFEIGNLFVIAFVSYFGAKLHRPRLIAAGCLVMSAGSFITAMPHFFQG----QYKYESTISHFSASVNGTENVLPCLTNASLAQ------------DSEIPTVESQAECEKASSSSLWLFVFLGNMLR-GIGETPVMPLGLSYLDDFSREENTAFYLALIQTVGIMGPMFGFMLGSFCAKLYVDIGTVDLDSITINYKDSRWVGAWWLGFLVTGGVMLLAGIPFWFLPKSLTRQGEPESEKKPGAPEGGEQERFIPDNNKHNPPASKPAPVTMS-----------ALAKDFLPSLKKLFSNTIYVLLVCTGLIQVSGFIGMITFKPKFMEQVYGQSASRAIFLIGIMNLPAVALGIVTGGFIMKRFKVNVLGAAKICIVASVLAFCSMLIQYFLQCDNSQVAGLTVTYQGAPEVSYQTETLISQCNIGCSCSLKHWDPICAS-NGVTYTSPCLAGCQTSTGIGKE--MVFHNCSCIG----------------------------------------------------EALLPYTNMSAVLGQCPRKSDCDFMFKIYMAVTVIGAFFSAVGATPGYIILLRSITPELKSLALGMHTLIVRTLGGIPPPIYFGALIDKTCLKWGLKQCGGRGACRIYDSGAFRNAFLGLIYALYSSSYLLFGLLYNRLSHREKKQALKDQLKAPEQDSCGVSTTNGNASSAIVKCENPDQETTI----------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VK84-1", "uniprot_id": "Q9VK84_DROME", "id": "Q9VK84-1", "name": "Solute carrier organic anion transporter family member", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------MAEVKRRDPNRPPGHYLCGMANWHPPWLQKYATTKMFMGVYGLLGTIQAMSYMYFIVTLTTLEKRFKIPSQTTGIILSGNEISQIMLSLILSYIGGQRNRPRWIAWGIVFCGLSCYILVLPHFIYGAGHEVLQFTKEY-QDSLLNGTTGSDHSFQNISSVKT------------ERLCGVDKTEDDCDDLFSYVPLVLIFLSQFVL-GVGNTLYYSLGQTYLDDNTKKTNTPLMLAVAMALRMIGPVVGFFFGFISLNTFIDP----TKTPLIDSKDPRWLGAWWLGWVILGTLMCLFSGLIGLFPKQLPKVNASRTNSHLPLALRQTKEELKREENLSLSSRFSSNAALDTIGAAAGANADLPKLKDFPRALMRLLRNKLLIFNILSAVFYILGASGFMTFLTKYMEVQFHKDAQSATIIVGPISIMGMVVGLIGSGMVLSKKKPSVSKVLMWNVIVGGISILGQISYAFLYCPNT-----------FSMTQAGQLNLTSNCNMNCSCEGISYTPVCHEPTDTTFFSACHAGCRG---YNATS-KLYEDCSCVVNDPAPKSAAQRLLNLLQPTPEPELDTTTYFDEYLSGVPLLDDNGDFDDQLLSRTRRSTSDSVIRPGICTKN--CNWSFWAFSITSMIVSWFGSSGRVGNVLVNYRAVAHEDKSFAQGLALMMISLLALIPGPIIFGRLIDSTCLVWT-KTCNGNGNCQLYDQTRFRYSLN------FLSCLLTFMGLLFDYLVWYYGRNLDIYGDKE----AKEEERANRKDQPITPLLAKKSEQE-----------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9W270-1", "uniprot_id": "Q9W270_DROME", "id": "Q9W270-1", "name": "Solute carrier organic anion transporter family member", "aln": "--------------------------------------------------------------------------------------------------------------------------MASEEIEASKFLKDKEAGINVADDEKRLNSSDTTCGFSIFRGPALQRFATAHMFVIVYGIASCFLAMAFTYFTGTITTMEKRFNIPTKISGLITVGNDISTVFSSAFLSYYASRGHRPRWVALGLIIIAIFCLLMLTPHIFYGPGEEALRLTEEY-GMSESFGAS--------LNITEK------------NDSLCHEKNSNCLERAGDYTPIVLFFIAQFIG-GIGCSLFYAPGLSYMDDNSASSKTPAMLSWSSFLRMLGPAMGFSMVSLCLRLYIDP----FKKPLITTNDPRWMGAWWIGWILLTFILTISAVFVGMFPKEMPRAKARRLKADG-------------EEDIPLAGRS---------------------FQDMLDSLKRLASNKVYVYNMLASILYLFGYMPYWIFTPKYIEIQYRQSASTSTMATGTWALGFSAAGILISGYVISKYKPSARAMAAWNFVVDYLTVAGMLCYVLVGCDES-----------DRANSLSIVPTGDSCSASCVCEYVYYAPVCSP-ENITFISACHAGCTDKAINELGK-TIYTGCRCMGNVSSIIS------------------------------------------LSNVTSLASQSQIAMDGACPVD--CNKQFLIFLAVMCFLKFVGATGRSSNLLLALRCVPSKDKTFSLGFGSMVYSVLAFIPSPIVFGWMLDSYCLVWG-KTCSSKGNCWIYDTKSLRYTMN------LVCASLIFLGSFWNIGVWYHAKDMKVFDEDEKTVQAKQSDDIELKEKPNDVVTKKK---------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VVH9-1", "uniprot_id": "SO74D_DROME", "id": "Q9VVH9-1", "name": "Solute carrier organic anion transporter family member 74D", "aln": "MTKSNGDVEAAAQVQSLGGKPSNGHGQLNGNGYHQNGGRRDSSQAFTPLLSQHNNGTTNGEVTTPPPSTVLYESTPSNNNEWKAPEDLGHLKNGLGNILSSNNNGTGNGHSLSEKYAHEQAPLTGGYKLPPRSSESEESDFDSDLNGGSSAESSSSCGLFGCRPRWARRFASTHVFMVVFLLAYILQGMYMTYFVSVITTIEKLFQIKSKTTGILLSASEMGQICTAMLLTYFAGRGHRPRWIACGMVLFSIAAFSCALPHFIFGEQLMHSSVILQQTQVSPPNNSFSSHWLNASSEQVNPNLCILGGNQTHSGSECNEERQLEQASHSKITVIVLCIFFGSLLSSGIGQTAVATLGIPYIDDNVGSKQSPMYMAVTIGMRILGPASGFIFGSFCTRWYVNFS-----NPGFDATDPRWIGAWWLGPVAIGSLMLLASIAMFSFPKQLRGKQKPPGQTATPAAP------VEPEEKPK--------------------------LKDFPKTVRRQLSNDILMFRTASCVFHLLPIAGLYTFLPKYLETQFRLATYDANMIAAFCGILVMGIGIVISGLFILKRKPTARGVAAWIAFTALVYSAGMIILMFIGCSMNDFAG----YKPSDGNSPALIEPTCSAALNCTCDKENFAPICAD--GKMYISACHAGCSSSSLRPSDNRTLYSDCACIP----------------------------------------------------------DAPEAVNGYCDNN---CKNFIYFILIFAICVFMHSTSEVGSMLLVMRCTHPKDKAMAMGVIQSAIGLFGNVPCPIIYGAVVDSACLIWK-SVCGKHGACSLYDADTFRQYFLG------ITAGIMFLAFLMDLVVWRKAHRIDIAPEDPQEGGPASNGRTLEVSESKQPITPAPDTTV-----------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : :*: *.: :. *:: . ::. : :::* ..: :**: :. * .. . **:: * . . : .::..:: *:* : . * .*:** . ::. :. : : * .* : . . ::: . : *.**:****:. : . . . :* : ::. .: :. * : :: : : * :* : : : : . : .:. .* .: : * . : . : * . . * *. : *:* . : *.* *** : .* *: * * : . : . :: : : *::. *. :. : *: :* .:* *: * . *. .* * *: : . . . . ", "identical_positions": 56, "similar_positions": 141, "identity": "5.95%" }, { "cls_id": "homologset.agr.MGI:1351901", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "E9PTA2-1", "uniprot_id": "TRPM2_RAT", "id": "E9PTA2-1", "name": "Transient receptor potential cation channel subfamily M member 2", "aln": "MEPLDQRRTDSDQEEGFGVQSRRATDLGMVPNLRRSNSSLCKSRRLLCSFSS-EKQENLSSWIPENIKKKECVYFVESSKLSDAGKVVCECGYTHEQHIEVAIKPHTFQGKEWDPKKHVHEMPTDAFGDIVFTGLSQKVGKYVRLSQDTSSIVIYQLMTQHWGLDVPSLLISVTGGAKNFNMKLRLKSIFRRGLVKVAQTTGAWIITGGSHTGVMKQVGEAVRDFSLSSSCKEGDVITIGIATWGTIHNREALIHPMGGFPAEYMLDEEGQGNLTCLDSNHSHFILVDDGTHGQYGVEIPLRTKLEKFISEQTKERGGVAIKIPIVCVVLEGGPGTLHTIYNAITNGTPCVIVEGSGRVADVIAQVAALPVSEITISLIQQKLSVFFQEMFETFTENQIVEWTKKIQDIVRRRQLLTVFREGKDGQQDVDVAILQALLKASRSQDHFGHENWDHQLKLAVAWNRVDIARSEIFTDEWQWKPSDLHPMMTAALISNKPEFVRLFLENGVRLKEFVTWDTLLCLYENLEPSCLFHSKLQKVLAEEHERLAYA--SETPRLQMHHVAQVLRELLGDSTQLLYPRPRYTDRPRLSLPMPHIKLNVQG-VSLRSLYKRSTGHVTFTIDPVRDLLIWAIIQNHRELAGIIWAQSQDCTAAALACSKILKELSKE--EEDTDSSEEMLALADEFEHRAIGVFTECYRKDEERAQKLLVRVSEAWGKTTCLQLALEAKDMKFVSHGGIQAFLTKVWWGQLCVDNGLWRIILCMLAFPLLFTGFISFR-------------------------------EKRLQALCR---------LARVRAFFNAPVVIFYLNILSYFAFLCLFAYVLMVDFQPSPSWCEYLIYLWLFSLVCEETRQLFYDPDGCGLMKMASLYFSDFWNKLDVGAILLFIAGLTCRLIP--ATLYPGRIILSLDFIMFCLRLMHIFTISKTLGPKIIIVKRMMKDVFFFLFLLAVWVVSFGVAKQAILIHNESRVDWIFRGVIYHSYLTIFGQIPTYIDGVNFSMDQCSPNGTDPYKPKCPESDWTGQAPAFPEWLTVTLLCLYLLFANILLLNLLIAMFNYTFQEVQEHTDQIWKFQRHDLIEEYHGRPPAPPPLILLSHLQLLIKRIVLKIPAKRHKQLKNKLEKNEEAALLSWELYLKENYLQNQQYQHKQRPEQKIQDISEKVDTMVDLLDMDRVKRSGSTEQRLASLEEQVTQMGRSLHWIVTTLKDSGFGSGAGALTLA-QRAFDEPDAELSIRKKGEEGGDGYHVSARHLLYPDARIMRFPVPNEKVPWEAEFLIYDPPFYTAEKKDATLTDPVGDTAEPLSKINYNVVDGLMDRCSFHGTYVVQYGFPLNPMGRTGLRGRGSLSWFGPNHTLQPVVTRWKRNQGGGICRKSVRKMLEVLVVKLPQSEHWALPGGSREPGKMLPRKLKQVLQQEYWVTFETLLRQGTEVYKGYVDDPRNTDNAWIETVAVSIHFQDQNDVELKRLEENLQTHDPKESARGLEMSTEWQVVDRRIPLYVNHKKILQKVASLFGAHF", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q91YD4-1", "uniprot_id": "TRPM2_MOUSE", "id": "Q91YD4-1", "name": "Transient receptor potential cation channel subfamily M member 2", "aln": "MESLDRRRTGSEQEEGFGVQSRRATDLGMVPNLRRSNSSLCKSRRFLCSFSS-EKQENLSSWIPENIKKKECVYFVESSKLSDAGKVVCACGYTHEQHLEVAIKPHTFQGKEWDPKKHVQEMPTDAFGDIVFTDLSQKVGKYVRVSQDTPSSVIYQLMTQHWGLDVPNLLISVTGGAKNFNMKLRLKSIFRRGLVKVAQTTGAWIITGGSHTGVMKQVGEAVRDFSLSSSCKEGEVITIGVATWGTIHNREGLIHPMGGFPAEYMLDEEGQGNLTCLDSNHSHFILVDDGTHGQYGVEIPLRTKLEKFISEQTKERGGVAIKIPIVCVVLEGGPGTLHTIYNAINNGTPCVIVEGSGRVADVIAQVATLPVSEITISLIQQKLSIFFQEMFETFTENQIVEWTKKIQDIVRRRQLLTIFREGKDGQQDVDVAILQALLKASRSQDHFGHENWDHQLKLAVAWNRVDIARSEIFTDEWQWKPADLHPMMTAALISNKPEFVRLFLENGVRLKEFVTWDTLLCLYENLEPSCLFHSKLQKVLAEE-QRLAYA--SATPRLHMHHVAQVLRELLGDSTQLLYPRPRYTDRPRLSMTVPHIKLNVQG-VSLRSLYKRSTGHVTFTIDPVRDLLIWAVIQNHRELAGIIWAQSQDCTAAALACSKILKELSKE--EEDTDSSEEMLALADEFEHRAIGVFTECYRKDEERAQKLLVRVSEAWGKTTCLQLALEAKDMKFVSHGGIQAFLTKVWWGQLCVDNGLWRIILCMLAFPLLFTGFISFR-------------------------------EKRLQALCR---------PARVRAFFNAPVVIFHMNILSYFAFLCLFAYVLMVDFQPSPSWCEYLIYLWLFSLVCEETRQLFYDPDGCGLMKMASLYFSDFWNKLDVGAILLFIVGLTCRLIP--ATLYPGRIILSLDFIMFCLRLMHIFTISKTLGPKIIIVKRMMKDVFFFLFLLAVWVVSFGVAKQAILIHNESRVDWIFRGVVYHSYLTIFGQIPTYIDGVNFSMDQCSPNGTDPYKPKCPESDWTGQAPAFPEWLTVTLLCLYLLFANILLLNLLIAMFNYTFQEVQEHTDQIWKFQRHDLIEEYHGRPPAPPPLILLSHLQLLIKRIVLKIPAKRHKQLKNKLEKNEETALLSWELYLKENYLQNQQYQQKQRPEQKIQDISEKVDTMVDLLDMDQVKRSGSTEQRLASLEEQVTQVTRALHWIVTTLKDSGFGSGAGALTLAPQRAFDEPDAELSIRRKVEEPGDGYHVSARHLLYPNARIMRFPVPNEKVPWAAEFLIYDPPFYTAEK-DVALTDPVGDTAEPLSKISYNVVDGPTDRRSFHGVYVVEYGFPLNPMGRTGLRGRGSLSWFGPNHTLQPVVTRWKRNQGGAICRKSVRKMLEVLVMKLPRSEHWALPGGSREPGEMLPRKLKRVLRQEFWVAFETLLMQGTEVYKGYVDDPRNTDNAWIETVAVSIHFQDQNDMELKRLEENLHTHDPKELTRDLKLSTEWQVVDRRIPLYANHKTILQKVASLFGAHF", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O94759-1", "uniprot_id": "TRPM2_HUMAN", "id": "O94759-1", "name": "Transient receptor potential cation channel subfamily M member 2", "aln": "MEPSALRKAGSEQEEGFEGLPRRVTDLGMVSNLRRSNSSLFKSWRLQCPFGNNDKQESLSSWIPENIKKKECVYFVESSKLSDAGKVVCQCGYTHEQHLEEATKPHTFQGTQWDPKKHVQEMPTDAFGDIVFTGLSQKVKKYVRVSQDTPSSVIYHLMTQHWGLDVPNLLISVTGGAKNFNMKPRLKSIFRRGLVKVAQTTGAWIITGGSHTGVMKQVGEAVRDFSLSSSYKEGELITIGVATWGTVHRREGLIHPTGSFPAEYILDEDGQGNLTCLDSNHSHFILVDDGTHGQYGVEIPLRTRLEKFISEQTKERGGVAIKIPIVCVVLEGGPGTLHTIDNATTNGTPCVVVEGSGRVADVIAQVANLPVSDITISLIQQKLSVFFQEMFETFTESRIVEWTKKIQDIVRRRQLLTVFREGKDGQQDVDVAILQALLKASRSQDHFGHENWDHQLKLAVAWNRVDIARSEIFMDEWQWKPSDLHPTMTAALISNKPEFVKLFLENGVQLKEFVTWDTLLYLYENLDPSCLFHSKLQKVLVEDPERPACA--PAAPRLQMHHVAQVLRELLGDFTQPLYPRPRHNDRLRLLLPVPHVKLNVQG-VSLRSLYKRSSGHVTFTMDPIRDLLIWAIVQNRRELAGIIWAQSQDCIAAALACSKILKELSKE--EEDTDSSEEMLALAEEYEHRAIGVFTECYRKDEERAQKLLTRVSEAWGKTTCLQLALEAKDMKFVSHGGIQAFLTKVWWGQLSVDNGLWRVTLCMLAFPLLLTGLISFR-------------------------------EKRLQDVGTP--------AARARAFFTAPVVVFHLNILSYFAFLCLFAYVLMVDFQPVPSWCECAIYLWLFSLVCEEMRQLFYDPDECGLMKKAALYFSDFWNKLDVGAILLFVAGLTCRLIP--ATLYPGRVILSLDFILFCLRLMHIFTISKTLGPKIIIVKRMMKDVFFFLFLLAVWVVSFGVAKQAILIHNERRVDWLFRGAVYHSYLTIFGQIPGYIDGVNFNPEHCSPNGTDPYKPKCPESDATQQRPAFPEWLTVLLLCLYLLFTNILLLNLLIAMFNYTFQQVQEHTDQIWKFQRHDLIEEYHGRPAAPPPFILLSHLQLFIKRVVLKTPAKRHKQLKNKLEKNEEAALLSWEIYLKENYLQNRQFQQKQRPEQKIEDISNKVDAMVDLLDLDPLKRSGSMEQRLASLEEQVAQTAQALHWIVRTLRASGFSSEADVPTLASQKAAEEPDAEPGGRKKTEEPGDSYHVNARHLLYPNCPVTRFPVPNEKVPWETEFLIYDPPFYTAERKDAAAMDPMGDTLEPLSTIQYNVVDGLRDRRSFHGPYTVQAGLPLNPMGRTGLRGRGSLSCFGPNHTLYPMVTRWRRNEDGAICRKSIKKMLEVLVVKLPLSEHWALPGGSREPGEMLPRKLKRILRQEHWPSFENLLKCGMEVYKGYMDDPRNTDNAWIETVAVSVHFQDQNDVELNRLNSNLHACDSGASIR-------WQVVDRRIPLYANHKTLLQKAAAEFGAHY", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A0R4IMY7-1", "uniprot_id": "TRPM2_DANRE", "id": "A0A0R4IMY7-1", "name": "Transient receptor potential cation channel subfamily M member 2", "aln": "-------------------MDEAALEPTLVQTLAVSTAKGGRYLSLSPSFQR----CSLASWIKENIKKKECCFYVE-----DGREGICKCGYPKVQHCDEAIKPEDYMGEQWDKHRHVRETPTDAFGDISFGGLGQKTGKYVRVSSDTSCENLYQLMTEQWKLRSPNLLISVTGGAKNFYIKTHLKDKFRRGLIKVAQTTGAWILTGGTHAGVMKHVGMAVRDYTLSSGSMEGQIVVIGVAPWGVIHNRSTLIHPEGRFPAYYSLDEQGQGRLSCLDINHTHFLLVDDGTQGHYGVEIELRARLEKLISKLSLGNRESGVTIPVVCVVLDGGPGTLNTIYNSMLNHTPCVVLEGSGRLADVIAHVASVPVSKVTMALINRLLKRFFMQEYKNFTELQIIEWTKKIQDILRMPHLLTVFRIDEDKNYDVDVAILQALLKASRSDEHAGRHCWERQLELAVAWNRVDIAESEIFTEESQWTSSDLHPAMFSALVGDKPEFVRLLLENGVCVREFLEREETLCELYSHLPSCFFLRKLAKRVQGGKMRRGQEPLPGSRKVCLSHVSEEVRHLLGSFTQPLYIASRYKP------TKDDVRLKVPSKGALDLPCSGEEWSADTVWDPGRDLFLWAVVQNNRELAEIGWEQCRDCIAAALAASKILRKLAQESGEDDSEEATEMLELANHYEKQAIGVFSECHSWDAQRAQKLLIRISPSWGRSTCLWLALEAHDKSFIAHSGVQALLTQIWCGELSVDNPHWKVLLCMIFFPLIYTGFLTFRRDEDIQRQAERTEQQKLAMESVFAGQSDGKIKRHLRGFSQKSELKPLNCSSRLMSFLKSPQVKFYWNIASYFGFLWLFAVVLMIDFQTSPSWRELLLYVWLTSLVCEEIRQLYHDFDGSGFRRKAKMYIKDLWNILDVLSIVLFIAGLICRLQASDTVFYIGKVILCIDFIIFCLRLMAIFSISRTLGPKIIIVRRMMLDLFFFMFLLSIWVVAYGVAKQGILIENEERLNWIIRGAVYEPYITIFGNFPTNIDNTLFDISSCSVNASDPLKPKCPMLNADN-TPVFPEWLTIMMLCVYLLFANILLLNLLIAIFNYTFQEVQDNTDTIWKFQRYELIKEYHSRPALPPPFILLSHLILFIRGVFLRDLPQRHKNFRQELEQTEEEELLSWEAYMKDNYLASTRQDESQSVEHRIHDTAEKVGAMSELLEREQEMVSATMAKRLARLEEQVSESAKALRWIIDALKSQGCKSKVQPPLMR-SKSSDRDDGDSSGQETDDE--EAPHMFARQLQYPDSTVRRFPVPEEKVSWEVNFSPYQPPVYNQQD---------------SSESDTSALDKHR-----------------NPGGRTGIRGKGALNTLGPNHILHPIFTRWR---------DAEHKVLEFLAVWEDAEKRWALLGGPAQPDEPLAQVLERILGKKLNEKTKTLLKAGEEVYKGYVDDSRNTDNAWVETSIITLHC-DKNTPLMADLNHMVESSLSSHQPLQ------WREVSSDACRCSYQREALRQIAHHHNTYF", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . . : :* .* *.:. : : .* .*:*** ******** ::** *. : :* ***.: ** : * **. : * :** ::**:* ******** * .*.**. ****:*.**.. :*:***::* * *.************ :* :**. *****:**********:***:*:****:** ****::***. **:::.**:*.**.:*.*. **** * *** * ***:***.*:*** **:**:******:*:***** **::***:**: : . .:.**:*****:******:** *: * ****::*****:*****:** :***.:*::**:: *. ** : ::.*** :*:*********:* :***:** .:* : ****************::* *:. *::**:***********.**** :* **..:**** * :**:.:*****:*:***** ::**: : * . ***:* ** * : * . . : :: : **:: :*.***. ** ** .*:. . .::*:* . :* . . . . ** ***::**::**.**** * * *.:** *****.****::*::* *:*::.: *** **:.:*::*****:**: * :****** *:* :**::*** *****:* .*::*.*:**:**::* *:*.*** *:: ***: ***: **:::** :::*: . :* :*:.:* * *: ** ***.** *** ***:***. *** * :*:** ****** ***::* * .*: : * :*:.*:** *** :*:**:.** *** . :.:* *::**.:***:****** **:**:*********:*** *:***:***::***::*****.***.** *::*::**.:*..*:****::* **.. *. . ** *.:** ***** : *.******: :**:****:**********:******:**::** ******::**:***.**. ***:****** *:*: :.*: .:***:::::**:.** ***** *:*:*** . : :..* *::*.* ::**.:* :**: : *.: :*** *****:: ::*:**: :*: .* * . : .:: :. *.: . :.. :* :. *: **:* **:. : *****:***.* .:* *:**.*. : * . ..:* ** ****:**:*:*. :**** * *:.***: .: :*:**.*.: .::*** **. :*.: *.: *:::* :: :.** * ******:**.*******:** :::* *:* : *: :.: . *: *. :: *:: * ..:::", "identical_positions": 703, "similar_positions": 414, "identity": "45.18%" }, { "cls_id": "homologset.agr.MGI:1351906", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9VK84-1", "uniprot_id": "Q9VK84_DROME", "id": "Q9VK84-1", "name": "Solute carrier organic anion transporter family member", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------MAEVKRRDPNRPPGHYLCGMANWHPPWLQKYATTKMFMGVYGLLGTIQAMSYMYFIVTLTTLEKRFKIPSQTTGIILSGNEISQIMLSLILSYIGGQRNRPRWIAWGIVFCGLSCYILVLPHFIYGAGHEV--------LQFTKEYQDSLLNGTTGSDHSFQNISSVKTERLCGVDKTED-----DCDDLFSYVPLVLIFLSQFVL-GVGNTLYYSLGQTYLDDNTKKTNTPLMLAVAMALRMIGPVVGFFFGFISLNTFIDP----TKTPLIDSKDPRWLGAWWLGWVILGTLMCLFSGLIGLFPKQLPKVNASRTNSHLPLALRQTKEELKREENLSLSSRFSSNAALDTIGAAAGANADLPKLKDFPRALMRLLRNKLLIFNILSAVFYILGASGFMTFLTKYMEVQFHKDAQSATIIVGPISIMGMVVGLIGSGMVLSKKKPSVSKVLMWNVIVGGISILGQISYAFLYCPNTFSMTQAGQLN-----------LTSNCNMNCSCEGISYTPVCHEPTDTTFFSACHAGCRG---YNATS-KLYEDCSCVVNDPAPKSAAQRLLNLLQPTPEPELDTTTYFDEYLSGVPLLDDNGDFDDQLLSRTRRSTSDSVIRPGICTKNCNWSFWAFSITSMIVSWFGSSGRVGNVLVNYRAVAHEDKSFAQGLALMMISLLALIPGPIIFGRLIDSTCLVWT-KTCNGNGNCQLYDQTRFRYSLNFLSCLLTFMGLLFDYLVWYYGRNLDIYGDKE----AKEEERANRKDQPITPLLAKKSEQE----------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9W270-1", "uniprot_id": "Q9W270_DROME", "id": "Q9W270-1", "name": "Solute carrier organic anion transporter family member", "aln": "--------------------------------------------------------------------------------------------------------------------------MASEEIEASKFLKDKEAGINVADDEKRLNSSDTTCGFSIFRGPALQRFATAHMFVIVYGIASCFLAMAFTYFTGTITTMEKRFNIPTKISGLITVGNDISTVFSSAFLSYYASRGHRPRWVALGLIIIAIFCLLMLTPHIFYGPGEEA--------LRLTEEYGMSESFGAS--------LNITEKNDSLCHEKNSN-----CLERAGDYTPIVLFFIAQFIG-GIGCSLFYAPGLSYMDDNSASSKTPAMLSWSSFLRMLGPAMGFSMVSLCLRLYIDP----FKKPLITTNDPRWMGAWWIGWILLTFILTISAVFVGMFPKEMPRAKARRLKADG-------------EEDIPLAGRS---------------------FQDMLDSLKRLASNKVYVYNMLASILYLFGYMPYWIFTPKYIEIQYRQSASTSTMATGTWALGFSAAGILISGYVISKYKPSARAMAAWNFVVDYLTVAGMLCYVLVGCDESDRANSLSIVP-----------TGDSCSASCVCEYVYYAPVCSP-ENITFISACHAGCTDKAINELGK-TIYTGCRCMGNVSSIIS------------------------------------------LSNVTSLASQSQIAMDGACPVDCNKQFLIFLAVMCFLKFVGATGRSSNLLLALRCVPSKDKTFSLGFGSMVYSVLAFIPSPIVFGWMLDSYCLVWG-KTCSSKGNCWIYDTKSLRYTMNLVCASLIFLGSFWNIGVWYHAKDMKVFDEDEKTVQAKQSDDIELKEKPNDVVTKKK--------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9QYE2-1", "uniprot_id": "SO1A6_RAT", "id": "Q9QYE2-1", "name": "Solute carrier organic anion transporter family member 1A6", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------MGEP-----EKRAGTHGIR--------CFAKIKVFLLALTWAYASKALSATYMNSMLTQIERRFNISTSIVGLINGSFEVGNLLLIIFVSYFGRKRHRPIMIGIGCAVMGLGCFIISLPHFLMG------------------RYEYETTISPTSNLSSNSFLCMENRTQTLKPTQDPA-----ECVKEMKSLMWIYVLVGNIIR-GIGETPIMPLGISYIEDFAKSENSPFYIGILEVGKITGPIAAIWLGSFCATIYVDMGSVNTDDLTITPTDTRCVGAWWIGFLVCAGLNILISIPFFFFPKTFPKEGPEDMANETKNDEGDKH---REKAKEEKRGIT----------------------KDFFLFMKSLSCNPIYMLCVLTSVLQVNGFVSIFTFKPKYLEHHYGKSSSEAIFLMGLYTLPSVCVGYLISGFIMKKFKITLKKAAFISYCLGMSECLLSLCNFMLTCDNVPIAGLTTSYEGIQQSFDMENTVLADCNTRCSCLTKTWDPVCGD-NGLAYITPCLAGCEKS-VGSGIN-MVLQDCSCIQSS------------------------------------------------------GNSSAVLGLCNKGPDCANKLQYFLIITVFCSFFYSLSLIPGYMIFLRCMKSEEKSLGIGLQAFCMRILGGILAPIYFGVLIDRTCLHWGTQKCGEPGACRTYEINSFRSIYLGLPAALRGSSYLPAFFILRLMRKFQFPGDINSPVTDHVEMMLTEKESEHTDVHRSPQVENDGELKTKL--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q99J94-1", "uniprot_id": "SO1A6_MOUSE", "id": "Q99J94-1", "name": "Solute carrier organic anion transporter family member 1A6", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------MGEP-----GKRVGIHRVR--------CFAKIKVFLLALIWAYISKILSGVYMSTMLTQLERQFNISTSIVGLINGSFEMGNLLVIVFVSYFGTKLHRPIMIGVGCAVMGLGCFIISLPHFLMG------------------RYEYETTISPTSNLSSNSFLCVENRSQTLKPTQDPA-----ECVKEIKSLMWIYVLVGNIIR-GIGETPIMPLGISYIEDFAKSENSPLYIGILEVGKMIGPILGYLMGPFCANIYVDTGSVNTDDLTITPTDTRWVGAWWIGFLVCAGVNVLTSIPFFFFPKTLPKEGLQDNGDGTENAKEEKH---RDKAKEENQGII----------------------KEFFLMMKNLFCNPIYMLCVLTSVLQVNGVANIVIYKPKYLEHHFGISTAKAVFLIGLYTTPSVSAGYLISGFIMKKLKITLKKAAIIALCLFMSECLLSLCNFMLTCDTTPIAGLTTSYEGIQQSFDMENKFLSDCNTRCNCLTKTWDPVCGN-NGLAYMSPCLAGCEKS-VGTGAN-MVFQNCSCIRSS------------------------------------------------------GNSSAVLGLCKKGPDCANKLQYFLIITVFCCFFYSLATIPGYMVFLRCMKSEEKSLGIGLQAFFMRLFAGIPAPIYFGALIDRTCLHWGTLKCGEPGACRTYEVSSFRRLYLGLPAALRGSIILPSFFILRLIRKLQIPGDTDSSEIELAETKPTEKESECTDMHKSSKVENDGELKTKL--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P46721-1", "uniprot_id": "SO1A2_HUMAN", "id": "P46721-1", "name": "Solute carrier organic anion transporter family member 1A2", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------MGET-----EKRIETHRIR--------CLSKLKMFLLAITCAFVSKTLSGSYMNSMLTQIERQFNIPTSLVGFINGSFEIGNLLLIIFVSYFGTKLHRPIMIGIGCVVMGLGCFLKSLPHFLMN------------------QYEYESTVSVSGNLSSNSFLCMENGTQILRPTQDPS-----ECTKEVKSLMWVYVLVGNIVR-GMGETPILPLGISYIEDFAKFENSPLYIGLVETGAIIGPLIGLLLASFCANVYVDTGFVNTDDLIITPTDTRWVGAWWFGFLICAGVNVLTAIPFFFLPNTLPKEGLETNADIIKNENEDKQ---KEEVKKEKYGIT----------------------KDFLPFMKSLSCNPIYMLFILVSVIQFNAFVNMISFMPKYLEQQYGISSSDAIFLMGIYNLPPICIGYIIGGLIMKKFKITVKQAAHIGCWLSLLEYLLYFLSFLMTCENSSVVGINTSYEGIPQDLYVENDIFADCNVDCNCPSKIWDPVCGN-NGLSYLSACLAGCETS-IGTGIN-MVFQNCSCIQTS------------------------------------------------------GNSSAVLGLCDKGPDCSLMLQYFLILSAMSSFIYSLAAIPGYMVLLRCMKSEEKSLGVGLHTFCTRVFAGIPAPIYFGALMDSTCLHWGTLKCGESGACRIYDSTTFRYIYLGLPAALRGSSFVPALIILILLRKCHLPGENASSGTELIETKVKGKENECKDIYQKSTVLKDDELKTKL--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0ACD6B7C1-1", "uniprot_id": "A0ACD6B7C1_DANRE", "id": "A0ACD6B7C1-1", "name": "Solute carrier organic anion transporter family member", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------MSEPTIEDNGKPTSQQELCSPEAPEEPRCSSLKIFIGALSFAYFSKTLCGTYMKSAITQIERRFDLSSSAVGLVDGSFEMGNLLFVAVVSHFGARLHRPRLIGMGCFLMAIGSALTGLPHVFMG------------------RYKFDTAVQGFANETVVIAPCQYPTNPSEHSIQHIDNTTGTDCVKDPGSSMWIYVFLGNALR-GIGETPVTPLGISYIDDFAKAENSAFYISCLQTIMLLGPMFGFLLGSMCAKLYVDIGFVSVDSVSITPQDARWVGAWWLGFFVSSAFLVLSGVPFWFLPRSLPKQGEEEKEIYNTDDANKEHSVLQTTHTMTLADIA----------------------KGFLPSLKRLLCTPAYFLLLCGIVLKFNSFIGLLTFKAKYMEQQFGQSASRANFLIGVLILPVVAVGIFLGGLLMKKYKLSVVAGAQLSFITSFTAFLLLLLHFGTKCDNVPVAGLTVSYNGTPYMPSDQRSLESQCNQDCSCSTSEWDPVCSD-SGITYMSPCLAGCTAS-TGQGKN-TVFHNCSCVLSPS--------------------------------------------------PAEGGRSVSLGQCPQGSACARSFTSYMAVSVLSSFINSLGTTPGYMIIIRCIAPELKSLALGIQTLVMRTLGGIPAPIYFGALIDTTCLKWGLKKCGGRGACRIYDSNMYRVIFLSLTTALSGCSYFFIIAVIVLLRRQFIKEEVK--ALQQMAGKQNEIELRSPEMQNPDGTKTDERDKNNTEG", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VVH9-1", "uniprot_id": "SO74D_DROME", "id": "Q9VVH9-1", "name": "Solute carrier organic anion transporter family member 74D", "aln": "MTKSNGDVEAAAQVQSLGGKPSNGHGQLNGNGYHQNGGRRDSSQAFTPLLSQHNNGTTNGEVTTPPPSTVLYESTPSNNNEWKAPEDLGHLKNGLGNILSSNNNGTGNGHSLSEKYAHEQAPLTGGYKLPPRSSESEESDFDSDLNGGSSAESSSSCGLFGCRPRWARRFASTHVFMVVFLLAYILQGMYMTYFVSVITTIEKLFQIKSKTTGILLSASEMGQICTAMLLTYFAGRGHRPRWIACGMVLFSIAAFSCALPHFIFGEQLMHSSVILQQTQVSPPNNSFSSHWLNASSEQVNPNLCILGGNQTHSGSECNEERQLEQASHSKITVIVLCIFFGSLLSSGIGQTAVATLGIPYIDDNVGSKQSPMYMAVTIGMRILGPASGFIFGSFCTRWYVNFS-----NPGFDATDPRWIGAWWLGPVAIGSLMLLASIAMFSFPKQLRGKQKPPGQTATP------------AAPVEPEEKP--------------------KLKDFPKTVRRQLSNDILMFRTASCVFHLLPIAGLYTFLPKYLETQFRLATYDANMIAAFCGILVMGIGIVISGLFILKRKPTARGVAAWIAFTALVYSAGMIILMFIGCSMNDFAGYKPSDGNSP----ALIEPTCSAALNCTCDKENFAPICAD--GKMYISACHAGCSSSSLRPSDNRTLYSDCACIPDAP--------------------------------------------------------EAVNGYCDNN---CKNFIYFILIFAICVFMHSTSEVGSMLLVMRCTHPKDKAMAMGVIQSAIGLFGNVPCPIIYGAVVDSACLIWK-SVCGKHGACSLYDADTFRQYFLGITAGIMFLAFLMDLVVWRKAHRIDIAPEDPQEGGPASNGRTLEVSESKQPITPAPDTTV----------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . :. ::*: . : *: :* :*: *.: :. *:: . ::. : .::: . : :** :. * . .: . **.: . . . : : .:... : *:* : . * .*::* ::. :. : ** . : :. ::: : . *.* :****:* . . : . . :*. : : : : . . :: . : .**:* :: : : : . * . .* .: * * : : * .. * * : *:* . :::.* *** . : .* *: . : : : :. : . . :: *. : *::. *. :. : ** :* ::* ** * *. * * *: * : : . : : . : . : ", "identical_positions": 59, "similar_positions": 151, "identity": "6.33%" }, { "cls_id": "homologset.agr.MGI:1351911", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D4ACG2-1", "uniprot_id": "D4ACG2_RAT", "id": "D4ACG2-1", "name": "2-hydroxyacyl-CoA lyase 2", "aln": "MGAWPCDSMMLARGGLSAEVESCVEEGGFPVGSLINRFFLMETTAAAASAGGFFPSFLLLAFGTLVAAVLGAAHRLGLFYQLMHKVDKTSIRHGGESVAAVLRAHGVRFVFTLVGGHISPLLVACEKLGIRVVDTRHEVTAVFAADAVARLTGTVGVAAVTAGPGLTNTVTAVKNAQVAQSPVLLLGGAASTLLQKRGALQAIDQMSLFRPLCKFCASVRRVRDIVPTLRAAMAAAQSGTPGPVFVELPLDVLYPYFMVEKEMIPAQLPKGLMGRVVVWYLQNCLANLFAGAWEPRPEGPLPLDIPQASPQQVQRCVEILSRAKRPLLVLGSQALLPPTPANKLRAAVETLGVPCFLGGMSRGLLGRNHPLHIRQNRSAALKKADVVVLAGAVCDFRLSYGRVLNRKSSIIIVNRNRDDMLLNSDIFWKPQEAVQGDVGSFMIKLVEGLQGQTWSSDWVEELRKADQQKEQTYRDKALLPVPQHLNPVRLLQQVEETLPDNALLVVDGGDFVATAAYLVQPRGPLRWLDPGAFGTLGVGAGFALGAKLCQPEAEVWCLFGDGAFGYSLIEFDTFVRHKVPVIALVGNDAGWTQISREQVPRLGSDVACSLAYTDYHKAAMGLGAQGLILSRDNEDQVVKVLRDGQKLCQEGHAVVVNILIGRTDFRDGSISV", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8BU33-1", "uniprot_id": "HACL2_MOUSE", "id": "Q8BU33-1", "name": "2-hydroxyacyl-CoA lyase 2", "aln": "----------------------------------------METSAAAASAGGFFPSFLLLAFGTLVAAVLGVAHRLGLFYQLMHKVDKTSIRHGGESVAAVLRAHGVRFVFTLVGGHISPLLVACEKLGIRVVDTRHEVTAVFAADAVARLTGTVGVAAVTAGPGLTNTVTAVKNAQVAQSPVLLLGGAASTLLQKRGALQAIDQMSLFRPLCKFCASVRRVRDIVPTLRTAIAAAQSGTPGPVFVELPLDVLYPYFMVEKEMIPTKLPNSLMGRVVVWYLQNCLANLFVGAWEPRPEGPLPLDIPQASPQQVQRCVEILSRAKRPLLVLGSQALLPPTPANKLRAAVETLGVPCFLGGMSRGLLGRNHPLHIRQNRSAALKKADVVVLAGAVCDFRLSYGRVLNRKSSIIIVNRNRDDLLLNSDIFWKPQEAVQGDVGSFMIKLVEGLQGQMWSSDWAEELRKADQQKEQTYRDKALMPVLQHLNPVWVLQQVEETLPDNALLVVDGGDFVATAAYLVQPRGPLRWLDPGAFGTLGVGAGFALGAKLCQPEAEVWCLFGDGAFGYSLIEFDTFVRHKVPVIALVGNDAGWTQISREQVPRLGSDVACSLAYTDYHKAAMGLGAQGLILSRDNKDQVVKVLREGQQLCQDGHAVVVNILIGRTDFRDGSISV", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A1L0T0-1", "uniprot_id": "HACL2_HUMAN", "id": "A1L0T0-1", "name": "2-hydroxyacyl-CoA lyase 2", "aln": "----------------------------------------METPAAAAPAGSLFPSFLLLACGTLVAALLGAAHRLGLFYQLLHKVDKASVRHGGENVAAVLRAHGVRFIFTLVGGHISPLLVACEKLGIRVVDTRHEVTAVFAADAMARLSGTVGVAAVTAGPGLTNTVTAVKNAQMAQSPILLLGGAASTLLQNRGALQAVDQLSLFRPLCKFCVSVRRVRDIVPTLRAAMAAAQSGTPGPVFVELPVDVLYPYFMVQKEMVPAKPPKGLVGRVVSWYLENYLANLFAGAWEPQPEGPLPLDIPQASPQQVQRCVEILSRAKRPLMVLGSQALLTPTSADKLRAAVETLGVPCFLGGMARGLLGRNHPLHIRENRSAALKKADVIVLAGTVCDFRLSYGRVLSHSSKIIIVNRNREEMLLNSDIFWKPQEAVQGDVGSFVLKLVEGLQGQTWAPDWVEELREADRQKEQTFREKAAMPVAQHLNPVQVLQLVEETLPDNSILVVDGGDFVGTAAHLVQPRGPLRWLDPGAFGTLGVGAGFALGAKLCRPDAEVWCLFGDGAFGYSLIEFDTFVRHKIPVMALVGNDAGWTQISREQVPSLGSNVACGLAYTDYHKAAMGLGARGLLLSRENEDQVVKVLHDAQQQCRDGHPVVVNILIGRTDFRDGSIAV", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6NV04-1", "uniprot_id": "HACL2_DANRE", "id": "Q6NV04-1", "name": "2-hydroxyacyl-CoA lyase 2", "aln": "----------------------------------------MDIS-----------MYLGCSLGAALGGVIFASYKLGLLYQLFHKTERQSPRHGGESVAEVLRSHGVKFVFTLVGGHISPILVACEKLGIRIVDTRHEATAVFAADAVARLSGTVGVAAVTAGPGLTNTVTAVKNAQMAESPLLLIGGAAATLLQGRGALQDIDQMSLFKPLCKFCASVRTVREIVPTVRKALAIAQSGTPGPVFIEFPIDTLYPYHVVEKEFAPKNTPKGLMGKIIAWYLKNHLSNLFAGAWESRDLSPLPVHIPHATDDQVQRCVELVSRAKKPVILLGSQATLPPTPADDIRKALESLGIPCFLGGMSRGLLGKNSPLHIRQNRRDALKDADLVLLAGTVCDFRLSYGRVLNRRSKIIAVNRDKSQLLKNSDMFWKPTVAIQGDAGSFLLNLSKALKGHRCPEEWPQSLKEGDNVKEKANRAKADEKTERHLNPLSVLHRVDELLAEDSIIVADGGDFVGSAAYIMRPRGPLCWLDPGAFGTLGVGGGFALGAKLCRPESEVWIVYGDGSLGYTVAEFDTFTRHKTPVIALVGNDACWSQISREQVPMLGSNVACGLAFTDYHVVADGYGGKGYLIGREDESQLEDIIKKAQKECKEGKAVLLNVLIGKTNFREGSISV", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *: . :* : *: :..:: .:::***:***:**.:: * *****.** ***:***:*:**********:**********:******.********:***:*************************:*:**:**:****:**** ***** :**:***:******.*** **:****:* *:* **********:*:*:*.****.:*:**: * : *:.*:*::: ***:* *:***.****.: .***:.**:*: :*******::****:*:::***** *.**.*:.:* *:*:**:*******:*****:* *****:** ***.**:::***:************.: *.** ***::.::* ***:**** *:***.***:::* :.*:*: . :* :.*::.*. **:: * ** . :****: :*: *:* *.:::::*.******.:**::::***** *************.*********:*::*** ::***::**:: *****.*** **:******* *:******** ***:***.**:**** .* * *.:* ::.*:::.*: .:::..*: *::*:.*::*:***:*:**:***:*", "identical_positions": 381, "similar_positions": 180, "identity": "56.7%" }, { "cls_id": "homologset.agr.MGI:1352447", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8VI47-1", "uniprot_id": "MRP2_MOUSE", "id": "Q8VI47-1", "name": "ATP-binding cassette sub-family C member 2", "aln": "--------MDEFCNSTFWNLSLLKSP-EADLPLCFEQTVLVWIPLGFLWLLAPWQLYRIYRSRTKRFAITKFY------LAKQVFVVCLLILAA----IDLSLALTEDTGQATIPP--VKYTNPILYLCTWLLVLV-IQHCRQCCIQKNSWFLSMFWILSLLCG-----IFQFQTLIRALLQDSK-SNMTYS------CLFFVSYGFQIVILILSAFSE--------SSDSTHAPSATASFLSSVTFSWYDSTVLKGYKHPLTIE-DVWDIE-ENLKAKSLTSKFKTIMTKDLQKARQALQRRLKKS-QQSPEGTSHGLTKKQSQSQDVLVLEDSKKKKKKSEATKDFPKSWLVKALFKTFYVVILKSFILKLAHDILLFLNPQLLKFLIG-------------------FVKDPDSY-PWVGYIYAILMFSVTLIQSFFLQCYFQFCFVLGMTVRTTIIASVYKKALTLSNLARRQYTIGETVNLMSVDSQKLMDVTNYIHLLWSSVLQIALSIFFLWRELGPSILAGVGLMVLLVPVNGVLATKIRKIQVQNMKNKDKRLKIMNEILSGIKILKYFAWEPSFKEQVNSIRK-KELRNLLRFSQLQTILIFILHLTPTLVSVITFSVYVLVDSQNVLNAEKAFTSITLFNILRFPLAMLPMVISSVIQASVSVDRLEQYLGSDDLDLSAIRHVCHFD-----KAVQFSEASFTWDRD----------------------LEATIQDVN-LDIKPGQLVAVVGTVGSGKSSLISAMLGEMENVHG--------HITIKGSIAYVPQQAWIQNGTIKDNILFGSEYDEKKYQRVIEACALLPDLEMLPGGDMAEIGEKGINLSGGQKHRVSLARATYQDADIYILDDPLSAVDTHVGKHIFNKVVG-PNGLLSGKTRILVTHGIHFLPQVDEIVVLGKGTILEKGSYSDLMDKKGVFAKNWKTFMKHSGPEGE---ATVDNDSEEEDGDCGLIPTVEEIPDDAASLTMRRENSLR--RTLSRSSRSGSRRGKSLKSSLKIKSVNALNKKEEVVKGQKLIKKEFVETGKVKFSIYLKYLQAVGWWSLLFIVIFYVLNYVAFIGTNLWLSAWTSDSEKQNGTDNSPSQRDMRIGVFGALGIAQGIFLLSS-SLWSIYACRNASKTLHRQLLTNILR-APMSFFDTTPTGRIVNRFAGDISTVDDTLPQTLRSWLLCFFGIVSTLVMICMATPIFIIIIIPLSILYVSVQVFYVATSRQLRRLDSVTKSPIYSHFSETVSGLPVIRAFEHQQRFLANSEKQIDTNQKCVFSWITSNRWLAIRLELVGNLIVFCSALLLVI---YKNSLTGDTVGFVLSNALNITQTLNWLVRMTSEVETNIVAVERINEYINVDNEAPWVT--DKKPPADWPKKGEIQFNNYQVRYRPELDLVLKGITCNIKSTEKVGVVGRTGAGKSSLTNCLFRILESAGGQIIIDGIDIASIGLHDLRGRLTIIPQDPILFSGNLRMNLDPFNKYSDEEIWRALELAHLKSFVAGLQLG-----------------LLHEVTEGGDNLSIGQRQLLCLGRAVLRKSKILVLDEATAAVDLETDSLIQTTIRNEFSQCTVITIAHRLHTIMDSDKIMVLDSGKIVEYGSPEELLSNM-GPFYLMAKEAGIESVNHTEL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q63120-1", "uniprot_id": "MRP2_RAT", "id": "Q63120-1", "name": "ATP-binding cassette sub-family C member 2", "aln": "--------MDKFCNSTFWDLSLLESP-EADLPLCFEQTVLVWIPLGFLWLLAPWQLYSVYRSRTKRSSITKFY------LAKQVFVVFLLILAA----IDLSLALTEDTGQATVPP--VRYTNPILYLCTWLLVLA-VQHSRQWCVRKNSWFLSLFWILSVLCG-----VFQFQTLIRALLKDSK-SNMAYS------YLFFVSYGFQIVLLILTAFSG--------PSDSTQTPSVTASFLSSITFSWYDRTVLKGYKHPLTLE-DVWDID-EGFKTRSVTSKFEAAMTKDLQKARQAFQRRLQKS-QRKPEATLHGLNKKQSQSQDVLVLEEAKKKSEK--TTKDYPKSWLIKSLFKTFHVVILKSFILKLIHDLLVFLNPQLLKLLIG-------------------FVKSSNSY-VWFGYICAILMFAVTLIQSFCLQSYFQHCFVLGMCVRTTVMSSIYKKALTLSNLARKQYTIGETVNLMSVDSQKLMDATNYMQLVWSSVIQITLSIFFLWRELGPSILAGVGVMVLLIPVNGVLATKIRNIQVQNMKNKDKRLKIMNEILSGIKILKYFAWEPSFQEQVQGIRK-KELKNLLRFGQLQSLLIFILQITPILVSVVTFSVYVLVDSANVLNAEKAFTSITLFNILRFPLSMLPMVTSSILQASVSVDRLERYLGGDDLDTSAIRRVSNFD-----KAVKFSEASFTWDPD----------------------LEATIQDVN-LDIKPGQLVAVVGTVGSGKSSLVSAMLGEMENVHG--------HITIQGSTAYVPQQSWIQNGTIKDNILFGSEYNEKKYQQVLKACALLPDLEILPGGDMAEIGEKGINLSGGQKQRVSLARAAYQDADIYILDDPLSAVDAHVGKHIFNKVVG-PNGLLAGKTRIFVTHGIHFLPQVDEIVVLGKGTILEKGSYRDLLDKKGVFARNWKTFMKHSGPEGE---ATVNNDSEAEDDDDGLIPTMEEIPEDAASLAMRRENSLR--RTLSRSSRSSSRRGKSLKNSLKIKNVNVLKEKEKEVEGQKLIKKEFVETGKVKFSIYLKYLQAVGWWSILFIILFYGLNNVAFIGSNLWLSAWTSDSDNLNGTNNSSSHRDMRIGVFGALGLAQGICLLIS-TLWSIYACRNASKALHGQLLTNILR-APMRFFDTTPTGRIVNRFSGDISTVDDLLPQTLRSWMMCFFGIAGTLVMICMATPVFAIIIIPLSILYISVQVFYVATSRQLRRLDSVTKSPIYSHFSETVTGLPIIRAFEHQQRFLAWNEKQIDINQKCVFSWITSNRWLAIRLELVGNLVVFCSALLLVI---YRKTLTGDVVGFVLSNALNITQTLNWLVRMTSEAETNIVAVERISEYINVENEAPWVT--DKRPPADWPRHGEIQFNNYQVRYRPELDLVLKGITCNIKSGEKVGVVGRTGAGKSSLTNCLFRILESAGGQIIIDGIDVASIGLHDLRERLTIIPQDPILFSGSLRMNLDPFNKYSDEEVWRALELAHLRSFVSGLQLG-----------------LLSEVTEGGDNLSIGQRQLLCLGRAVLRKSKILVLDEATAAVDLETDSLIQTTIRKEFSQCTVITIAHRLHTIMDSDKIMVLDNGKIVEYGSPEELLSNR-GSFYLMAKEAGIENVNHTEL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q92887-1", "uniprot_id": "MRP2_HUMAN", "id": "Q92887-1", "name": "ATP-binding cassette sub-family C member 2", "aln": "-------MLEKFCNSTFWNSSFLDSP-EADLPLCFEQTVLVWIPLGYLWLLAPWQLLHVYKSRTKRSSTTKLY------LAKQVFVGFLLILAA----IELALVLTEDSGQATVPA--VRYTNPSLYLGTWLLVLL-IQYSRQWCVQKNSWFLSLFWILSILCG-----TFQFQTLIRTLLQGDN-SNLAYS------CLFFISYGFQILILIFSAFSE--------NNESSNNPSSIASFLSSITYSWYDSIILKGYKRPLTLE-DVWEVD-EEMKTKTLVSKFETHMKRELQKARRALQRRQEKSSQQNSGARLPGLNKNQSQSQDALVLEDVEKKKKKSGTKKDVPKSWLMKALFKTFYMVLLKSFLLKLVNDIFTFVSPQLLKLLIS-------------------FASDRDTY-LWIGYLCAILLFTAALIQSFCLQCYFQLCFKLGVKVRTAIMASVYKKALTLSNLARKEYTVGETVNLMSVDAQKLMDVTNFMHMLWSSVLQIVLSIFFLWRELGPSVLAGVGVMVLVIPINAILSTKSKTIQVKNMKNKDKRLKIMNEILSGIKILKYFAWEPSFRDQVQNLRK-KELKNLLAFSQLQCVVIFVFQLTPVLVSVVTFSVYVLVDSNNILDAQKAFTSITLFNILRFPLSMLPMMISSMLQASVSTERLEKYLGGDDLDTSAIRHDCNFD-----KAMQFSEASFTWEHD----------------------SEATVRDVN-LDIMAGQLVAVIGPVGSGKSSLISAMLGEMENVHG--------HITIKGTTAYVPQQSWIQNGTIKDNILFGTEFNEKRYQQVLEACALLPDLEMLPGGDLAEIGEKGINLSGGQKQRISLARATYQNLDIYLLDDPLSAVDAHVGKHIFNKVLG-PNGLLKGKTRLLVTHSMHFLPQVDEIVVLGNGTIVEKGSYSALLAKKGEFAKNLKTFLRHTGPEEE---ATVHDGSEEEDDDYGLISSVEEIPEDAASITMRRENSFR--RTLSRSSRSNGRHLKSLRNSLKTRNVNSLKEDEELVKGQKLIKKEFIETGKVKFSIYLEYLQAIGLFSIFFIILAFVMNSVAFIGSNLWLSAWTSDSKIFNSTDYPASQRDMRVGVYGALGLAQGIFVFIA-HFWSAFGFVHASNILHKQLLNNILR-APMRFFDTTPTGRIVNRFAGDISTVDDTLPQSLRSWITCFLGIISTLVMICMATPVFTIIVIPLGIIYVSVQMFYVSTSRQLRRLDSVTRSPIYSHFSETVSGLPVIRAFEHQQRFLKHNEVRIDTNQKCVFSWITSNRWLAIRLELVGNLTVFFSALMMVI---YRDTLSGDTVGFVLSNALNITQTLNWLVRMTSEIETNIVAVERITEYTKVENEAPWVT--DKRPPPDWPSKGKIQFNNYQVRYRPELDLVLRGITCDIGSMEKIGVVGRTGAGKSSLTNCLFRILEAAGGQIIIDGVDIASIGLHDLREKLTIIPQDPILFSGSLRMNLDPFNNYSDEEIWKALELAHLKSFVASLQLG-----------------LSHEVTEAGGNLSIGQRQLLCLGRALLRKSKILVLDEATAAVDLETDNLIQTTIQNEFAHCTVITIAHRLHTIMDSDKVMVLDNGKIIECGSPEELLQIP-GPFYFMAKEAGIENVNSTKF", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q7KTC0-1", "uniprot_id": "Q7KTC0_DROME", "id": "Q7KTC0-1", "name": "ABC-type glutathione-S-conjugate transporter", "aln": "MADDTSSPMDRFCGSTFWNATETWYTNDPDFTPCFEQTALVWTPCAFYWAFVIFDFYYLKASLDRNIPWNKLN------VSKALVNLGLLVITA----LDLIMALVKKGGDSELPLYDLDVWGPIIKFATFLLLFIFIPLNRKYGVQTTGCQFIFWFLLTVLSIPRCRTEVRLDAERQKILNSQQPSEQDFSWEEYQFVSFFIFFTFTSIMLILNCFADGMPRQTKYQRGENEIPELSASFLSRITYQWFDKMALKGYRNPLEEK-DLWDLR-PQDSCSEVMPIFAHHWNQNVRKNYKNKAR----------------VEPKAQFSNGNVTFEN--PHGEKNGRKKGMAS--IMPPIYKSFGGVFLFGALMKLFTDTLTFAQPQVLSLIIS-------------------FVEAQDAEPEWKGILYAVLLFVLAAAQTFILGQYFHRMFIVGLRIRTALINAIYRKALRISNSTKKESTVGEIVNLMAVDAQRFMELTTYLNMIWSAPLQIGLALYFLWQQLGPSVLAGLAVMIILIPVNGVIASRIKTYQIRQMKYKDERVKLMNEVLSGIKVLKLYAWEPSFEKQVLDIRD-KEIATLRSTAYLNAGTSFLWSCAPFLVSLVTFATYVLIDENNVLDATKTFVSLSLFNILRFPLTMLPMLITNLVQTQVSVNRINKFLNSEELDPNSVLHDSSKP-----HPMSIENGEFSWG------------------------DEITLRNIN-IEVKKGSLVALVGTVGSGKSSVVQAFLGEMEKLAG--------VVNTVGKLAYVPQQAWIQNATVRDNILFGQTYDRKRYNKVIDACALRADIDILSAGDLTEIGEKGINLSGGQKQRISLARAVYSDADLYLLDDPLSAVDAHVGKHIFEEVIG-PKGILARKSRVLVTHGVTFLPQVDSIYVIKMGEISESGTFDQLVKNKGAFADFIIQHLQEGNEEEEEL-NQIKRQISSTADVPELLGTVEKAIKLARTESLSDSISVTSADSLMGGGGSLRRRTKRQDSHDSVASAASLKKKQE-VEG-KLIETEKSQTGGVEFAVYKHYIKSVGIFLSVATLVLNFVFQAFQIGSNLWLTQWANDQNVANDTG----LRDMYLGVYGAFGFGQGVLAYFA-VVIVYLGGFQAAKTIHNELLAVIIRGSVCRFFDITPIGRLLNSFSGDMDVVDEELPATMDSFMTFIFMVLATIVVISLSTPIFLAVIVPIAFLYYFAQRFYVATSRQLMRLESVSRSPIYSHFSETVTGASTIRAYNVGDRFIEESDAKVDKNQVCKYPSVIANRWLAIRLEMVGNLIILFASLFAVL---GGQTNPG-LVGLSVSYALQVTQTLNWLVRMSSDIETNIVSVERIKEYGETKQEAPWELEQDKNKPKNWPQEGRVEFQNFQVRYREGLDLVLRGVSFNIQGGEKVGIVGRTGAGKSSLTLALFRIIEAAGGRISIDGVDIASMGLHMLRSRLTIIPQDPVLFSGSLRINLDPFEIKTDDEIWKALELSHLKSFVKSLAAG-----------------LNHEIAEGGENLSVGQRQLVCLARALLRKTKVLVLDEATAAVDLETDDLIQKTIRTEFKECTVLTIAHRLNTILDSDKVIVLDKGQIIEFASPTELLDNPKSAFYSMAKDANLV-------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P14772-1", "uniprot_id": "BPT1_YEAST", "id": "P14772-1", "name": "Bile pigment transporter 1", "aln": "---MSSLEVVDGCPYGYRP---YPDSGTNALNPCFIS-VISAWQAVFFLLIGSYQLWKLYKNNKVPPRFKNFPTLPSKINSRHLTHLTNVCFQSTLIICELALVSQSSDRVYPFILKKALYLNLLFNLGISLPTQY-LAYFKSTFSMGNQLFYYMFQILLQLFLILQRYYHGSSNERLTVISGQTAMILEVLLLFNSVAIFIYDLCIFEPINELSEYYK------------KNGWYPPVHVLSYITFIWMNKLIVETYRNKKIKDPNQLPLPPVDLNIKSISKEFKANWELEKWL----------------------------------------------------NRN-SLWRAIWKSFGRTISVAMLYETTSDLLSVVQPQFLRIFID-----------------GLNPETSSKYPPLNGVFIALTLFVISVVSVFLTNQFYIGIFEAGLGIRGSLASLVYQKSLRLTLAERNEKSTGDILNLMSVDVLRIQRFFENAQTIIGAPIQIIVVLTSLYWLLGKAVIGGLVTMAIMMPINAFLSRKVKKLSKTQMKYKDMRIKTITELLNAIKSIKLYAWEEPMMARLNHVRNDMELKNFRKIGIVSNLIYFAWNCVPLMVTCSTFGLFSLFS-DSPLSPAIVFPSLSLFNILNSAIYSVPSMINTIIETSVSMERLKSFLLSDEIDDSFIERIDPSADERALPAIEMNNITFLWKSKEVLTSSQSGDNLRTDEESIIGSSQIALKNIDHFEAKRGDLVCVVGRVGAGKSTFLKAILGQLPCMSGSRDSIPPKLIIRSSSVAYCSQESWIMNASVRENILFGHKFDQDYYDLTIKACQLLPDLKILPDGDETLVGEKGISLSGGQKARLSLARAVYSRADIYLLDDILSAVDAEVSKNIIEYVLIGKTALLKNKTIILTTNTVSILKHSQMIYALENGEIVEQGNYEDVMNRKNNTSKLKKLLEEFDSPIDNGNESDVQTEHRSESEVDEPLQLKVTESETEDEVVTESELELI--------------KANSRRASLATLRPRPFVGAQLDSVKKTAQKAEKTEVGRVKTKIYLAYIKACGVLGVVLFFLFMILTRVFDLAENFWLKYWSESNEKNGSNE----RVWMFVGVYSLIGVASAAFNNLRSIMMLLYCSIRGSKKLHESMAKSVIR-SPMTFFETTPVGRIINRFSSDMDAVDSNLQYIFSFFFKSILTYLVTVILVGYNMPWFLVFNMFLVVIYIYYQTFYIVLSRELKRLISISYSPIMSLMSESLNGYSIIDAYDHFERFIYLNYEKIQYNVDFVFNFRSTNRWLSVRLQTIGATIVLATAILALATMNTKRQLSSGMVGLLMSYSLEVTGSLTWIVRTTVTIETNIVSVERIVEYCELPPEAQSINP-EKRPDENWPSKGGIEFKNYSTKYRENLDPVLNNINVKIEPCEKVGIVGRTGAGKSTLSLALFRILEPTEGKIIIDGIDISDIGLFDLRSHLAIIPQDAQAFEGTVKTNLDPFNRYSEDELKRAVEQAHLKPHLEKMLHSKPRGDDSNEEDGNVNDILDVKINENGSNLSVGQRQLLCLARALLNRSKILVLDEATASVDMETDKIIQDTIRREFKDRTILTIAHRIDTVLDSDKIIVLDQGSVREFDSPSKLLSDKTSIFYSLCEKGGYLK------", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P39109-1", "uniprot_id": "YCFI_YEAST", "id": "P39109-1", "name": "Metal resistance protein YCF1", "aln": "---MAGNLVSWACKLCRSPEGFGPISFYGDFTQCFIDGVILNLSAIFMITFGIRDLVNLCKKKHSGIKYRRN----WIIVSRMALVLLEIAFVS------LASLNISKEEAENFTIVS-QYASTMLSLFVALALHW-IEYDRSVVANTVLLFYWLFETFGNFAKLINILIRHTYEG--IWYSGQTGFILTLFQVITCASILLLEALPKKPLMPHQHIHQT-------LTRRKPNPYDSANIFSRITFSWMSGLMKTGY-EKYLVEADLYKLP-RNFSSEELSQKLEKNWENELKQ----------------------------------------------------KSNPSLSWAICRTFGSKMLLAAFFKAIHDVLAFTQPQLLRILIKFVTDYNSERQDDHSSLQGFENNHPQKLPIVRGFLIAFAMFLVGFTQTSVLHQYFLNVFNTGMYIKSALTALIYQKSLVLSNEASGLSSTGDIVNLMSVDVQKLQDLTQWLNLIWSGPFQIIICLYSLYKLLGNSMWVGVIILVIMMPLNSFLMRIQKKLQKSQMKYKDERTRVISEILNNIKSLKLYAWEKPYREKLEEVRNNKELKNLTKLGCYMAVTSFQFNIVPFLVSCCTFAVFVYTE-DRALTTDLVFPALTLFNLLSFPLMIIPMVLNSFIEASVSIGRLFTFFTNEELQPDSVQRLPKVKNIGDVAINIGDDATFLWQRK--------------------PEYKVALKNIN-FQAKKGNLTCIVGKVGSGKTALLSCMLGDLFRVKG--------FATVHGSVAYVSQVPWIMNGTVKENILFGHRYDAEFYEKTIKACALTIDLAILMDGDKTLVGEKGISLSGGQKARLSLARAVYARADTYLLDDPLAAVDEHVARHLIEHVLG-PNGLLHTKTKVLATNKVSALSIADSIALLDNGEITQQGTYDEIT--KDADSPLWKLLNNYGK-KNNGKSNEFG--DSSESSVRESSIPVEGELEQLQKLNDLDFGNSD--------------AISLRRASDATLGSIDFG------DDENIAKREHREQGKVKWNIYLEYAKACNPKSVCVFILFIVISMFLSVMGNVWLKHWSEVNSRYGSNP----NAARYLAIYFALGIGSALATLIQTIVLWVFCTIHASKYLHNLMTNSVLR-APMTFFETTPIGRILNRFSNDIYKVDALLGRTFSQFFVNAVKVTFTITVICATTWQFIFIIIPLSVFYIYYQQYYLRTSRELRRLDSITRSPIYSHFQETLGGLATVRGYSQQKRFSHINQCRIDNNMSAFYPSINANRWLAYRLELIGSIIILGAATLSVFRLKQG-TLTAGMVGLSLSYALQITQTLNWIVRMTVEVETNIVSVERIKEYADLKSEAPLIVE-GHRPPKEWPSQGDIKFNNYSTRYRPELDLVLKHINIHIKPNEKVGIVGRTGAGKSSLTLALFRMIEASEGNIVIDNIAINEIGLYDLRHKLSIIPQDSQVFEGTVRENIDPINQYTDEAIWRALELSHLKEHVLSMS----------------NDGLDAQLTEGGGNLSVGQRQLLCLARAMLVPSKILVLDEATAAVDVETDKVVQETIRTAFKDRTILTIAHRLNTIMDSDRIIVLDNGKVAEFDSPGQLLSDNKSLFYSLCMEAGLVNEN----", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : * . : ** . .: : : :: : . . :: : : : * .. . . : : * : :. :: : : ... :: : . . .:* :*: * . * . . : : . : : : . : .: ::* : . : : * : . .**.* ::* . . * : *. :* . :: * *: :: :: :*:*:* :: : *: :***:** :: : : .. :** : : *: ** :: *: : :::*:*..: :. . :** ** * : :.*:*. ** :* :*** . :: :*. *: .: . * .* :*: **. : . * . .* :::***:* .: :* : ...:::.** *: :: .:::: . : : .: * * : :::::: :: *.*..::* **:**::.:..:**:: : * .. ** .* .** *.::::***** :: . *: .:.** * *: :* ** : :*****.****** *:*****.* * *:*** *:*** .*.::::: *: ..:* *: ::.*: : * : * : * * :.*.: : *. : . : . . . . : . : * : * *: :* * :: . .: : : *.**. *:. .. ... :.:: :*.... . ..:: :* : ::* : **: ** **::* *:.*: ** * : :: . *: :: * . : : .:* * :*: **:* ** *:: *** * :.*:: * . : .:. .** . ::: * : :****: **: :* :: :: : : .. **: :* :*::* :*.*:** : *****:**** ** . ** :. :** .* ::*:*:..:** ** **. :. .* **:*:*********:*: .***::*.: *.* **.: : .:**. ** :*:*****. *.*.:: *:**:: ::: : :*:* :**: .: : * :: * * ***:*****:**.**:* :*:********:**:***.::* **: * . *::*****:.*::***:::***.*.: * ** :**. . ** :. ... ", "identical_positions": 316, "similar_positions": 438, "identity": "18.85%" }, { "cls_id": "homologset.agr.MGI:1352448", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I6G7P9-1", "uniprot_id": "A0A8I6G7P9_RAT", "id": "A0A8I6G7P9-1", "name": "", "aln": "---------------------------------------------------------------------------------------MNI-MENSKEQELQTLGSRVWDNPAYSSPPSPNGTPRICTVSSVALPETQPKKPEVRRQEKTPRVP----VSGCCLLICRGIRG----------------------------------------LWGTTLTENTAENRELY---VKTTLR--ELVVYIVFLVDVCLLTYGMTSSSAYYYTKVMSELF----LHTPSESAVSFQTISSMSDFWDFAQGPLLDSLYWTKWYNNQSLG--------------------------------------------------------------------------------------------------SSSHSFIYYEN-LLLGVPRLRQLRVRND------SCVVHEDFREDILNCYDVYSPDKEDQLPFGPLNGTAWTYHSQN-ELGGSSHWGRLTSYSG-GGYYLDLPGSRQASAEALQGLQEGLWLDRGTRVVFIDFSVYNANINLFCILRLVVEFPATGGAIPSWQIRTVKLIRYVNNWDFFIVGCEVIFCIFIFYYVVEEILEIRVHRFRYLSS-VWNILDLVVILLSIVAVGFHVFRTLEVNRLMGELLQQ-PDTYPDFEFLAFWQTQYNNMNAVNLFFAWIKIFKYISFNKTMTQLSSTLARCAKDILGFAIMFFIVFFAYAQLGYLLFGTQVESFSTFVKCIFTQFRIILGDFDYN---AIDNANRILGPVYFITYVFFVFFVLLNMFLAIINDTYSEVKEELAGQ-RDQLQLSDLLKQSYSKTLQRLRLRKERVSDVQKVLKGGEPEIQFEDFTNTLRELGHAEREISEVSAAFTRFDRDGDHILDEEDQAQMRQGLEEERMTLSAETENLGRSVGHSPPGELDAEAARGRSWVSGEEFDMLTRRVLQLQRVLEGVVSQVDALSSKLKMLERKGELAPSPGMEEPAVWENPYNPS--------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A2A259-1", "uniprot_id": "PK2L1_MOUSE", "id": "A2A259-1", "name": "Polycystin-2-like protein 1", "aln": "---------------------------------------------------------------------------------------MNS-MESPKNQELQTLGNRAWDNPAYSDPPSPNRTLRICTVSSVALPETQPKKPEVRCQEKTQRTL----VSSCCLHICRSIRG----------------------------------------LWGTTLTENTAENRELY---VKTTLR--ELVVYIVFLVDICLLTYGMTSSSAYYYTKVMSELF----LHTPSDSGVSFQTISSMSDFWDFAQGPLLDSLYWTKWYNNQSLG--------------------------------------------------------------------------------------------------RGSHSFIYYEN-LLLGAPRLRQLRVRND------SCVVHEDFREDILNCYDVYSPDKEDQLPFGPQNGTAWTYHSQN-ELGGSSHWGRLTSYSG-GGYYLDLPGSRQASAEALQGLQEGLWLDRGTRVVFIDFSVYNANINLFCILRLVVEFPATGGTIPSWQIRTVKLIRYVNNWDFFIVGCEVVFCVFIFYYVVEEILEIHLHRLRYLSS-VWNILDLVVILLSIVAVGFHIFRTLEVNRLMGKLLQQ-PDTYADFEFLAFWQTQYNNMNAVNLFFAWIKIFKYISFNKTMTQLSSTLARCAKDILGFAIMFFIVFFAYAQLGYLLFGTQVENFSTFVKCIFTQFRIILGDFDYN---AIDNANRILGPVYFVTYVFFVFFVLLNMFLAIINDTYSEVKEELAGQ-KDQLQLSDFLKQSYNKTLLRLRLRKERVSDVQKVLKGGEPEIQFEDFTSTLRELGHEEHEI---TAAFTRFDQDGDHILDEEEQEQMRQGLEEERVTLNAEIENLGRSVGHSPPGELGAEAARGQSWVSGEEFDMLTRRVLQLQCVLEGVVSQIDAVGSKLKMLERKGELAPSPGMGEPAVWENLYNPS--------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9P0L9-1", "uniprot_id": "PK2L1_HUMAN", "id": "Q9P0L9-1", "name": "Polycystin-2-like protein 1", "aln": "---------------------------------------------------------------------------------------MNA-VGSPEGQELQKLGSGAWDNPAYSGPPSPHGTLRVCTISSTGPLQPQPKKPEDEPQETAYRTQ----VSSCCLHICQGIRG----------------------------------------LWGTTLTENTAENRELY---IKTTLR--ELLVYIVFLVDICLLTYGMTSSSAYYYTKVMSELF----LHTPSDTGVSFQAISSMADFWDFAQGPLLDSLYWTKWYNNQSLG--------------------------------------------------------------------------------------------------HGSHSFIYYEN-MLLGVPRLRQLKVRND------SCVVHEDFREDILSCYDVYSPDKEEQLPFGPFNGTAWTYHSQD-ELGGFSHWGRLTSYSG-GGYYLDLPGSRQGSAEALRALQEGLWLDRGTRVVFIDFSVYNANINLFCVLRLVVEFPATGGAIPSWQIRTVKLIRYVSNWDFFIVGCEVIFCVFIFYYVVEEILELHIHRLRYLSS-IWNILDLVVILLSIVAVGFHIFRTLEVNRLMGKLLQQ-PNTYADFEFLAFWQTQYNNMNAVNLFFAWIKIFKYISFNKTMTQLSSTLARCAKDILGFAVMFFIVFFAYAQLGYLLFGTQVENFSTFIKCIFTQFRIILGDFDYN---AIDNANRILGPAYFVTYVFFVFFVLLNMFLAIINDTYSEVKEELAGQ-KDELQLSDLLKQGYNKTLLRLRLRKERVSDVQKVLQGGEQEIQFEDFTNTLRELGHAEHEITELTATFTKFDRDGNRILDEKEQEKMRQDLEEERVALNTEIEKLGRSIVSSPQGKSGPEAARAGGWVSGEEFYMLTRRVLQLETVLEGVVSQIDAVGSKLKMLERKGWLAPSPGVKEQAIWKHPQPAPA-----VTPDPWGVQGGQESEVPYKREEEALEERRLSRGEIPTLQRS---", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8N7UVH6-1", "uniprot_id": "A0A8N7UVH6_DANRE", "id": "A0A8N7UVH6-1", "name": "", "aln": "--------------------------MGGHDAGSQHQFTGIAKYFNSYTITGRRNTKDEPLLSQNHCPVLTEVIQAKRELFTTMQHFSNR-PENHLSCEMESFGHGGWVNQAFSGSPAAVRRP-VSTIYSPQPGFHSPLENPYLNQDKARTMPNEDKKSGCCSFFFRAIKG----------------------------------------LWGTALRKDTKENPELN---VKANLK--ELLIYIVFLVDLCLLTYGMTSSATYYYTKAMTDLF----VNLPGSNGMSFSSIGCMNDVWTYMEGPLLDNLYWTKWYNDEPLE--------------------------------------------------------------------------------------------------NGNQSFIYYEN-LLLGVPRVRQLKVKQN------SCKVPTDFKKEISDCFDVYNIKKEDDGAFGLINGTAWQYHSEK-EIKGSSHWGLLTTYSG-AGFYQDLTTTRDESAALLEDLRENLWLDRGTRVLFIDFTAYNANINLFCVIRLVVEFPATGGAIPSYQIRTVKLIRYVTTWDYFIIGCEIVFCVFILYYIVEEILEFRIHKLSHFTS-IWNILDIVVILLAVVAIVFSAFRTIKVDGLLGNLLKQ-PDIYADFEFLAFWQTQYNNMNAVNLFFAWIKIFKYISFNKTMTQLTSTLARCALDIFGFAIMFFIVFFAYAQLGYLLFGTEVETFSTFNKCIFTQFRIILGDFDYD---AIDRANRVLGPIYFFSYVFFVFFVLLNMFLAIINDTYSEVKSELASQ-KDEFQIADLIKQSYAKTFMKLKLKKEKISDVQKALDSGASELEFKDFRNALKEMGHSDREIS---AAFSKFDQDGNQTLDKQEQENMKQELEEKRDALSAELRDLENSVEP---------AEEHRNTVPPEDYQRLVHKVSQLENSVSAIMSKLDFVMEKMRLQTFN---TESRDMDKQTNRDDESRPASGGNIHVNLERVLAQGPSWSLTGPMGSARNRLYPDVGWPVVTENNTSARH", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VVZ8-1", "uniprot_id": "Q9VVZ8_DROME", "id": "Q9VVZ8-1", "name": "", "aln": "-----------------------------------------------------------------MAKKFSNIIFYLTLIIIAICVACIW-MFSGFRHEYGKFNMILVAFLAVTLLQILIFTPIKFTIMSLDAAFWP--AHQAPETP-DENAN----VDTFMDNLRLRLRT----------------------------------------LRSELMITERHRNERVN---LKYRLITEELWLTGKLFLVYFFMALAFFDELLYFNTEATELLF----QCN-HGDAFGLLSVGDVPDIYFFVVSSLVL------AFTDGKNT--------------------------------------------------------------------------------------------------SGGAPWIHAEGTRLLGVVRLRQLRTESNRLGLSLPVFTERDFSESWTLPYERVPYTDKYWPIYTPWLPSVS--VARDNLLMGINHVGHMFNYPESKGYKVLLSDTRHKSLKIIDYLMKKNWLDANTTALFMDFSLYNADANTFTVCTLWVEKFPYQYPDGHTRIESHTFVEQLREFTKFGMLMVFVFVVTWLQFTKAFFLKVWYD-PRQLKT-LWVQVDAMIVALSLVVGMIMSVRDNLVQKMIKSVEIAVVVDFLDFREPAQLAYLEDVVTGLAVALVTMRLWKVLQFSATFQLFTKTIAMAWDALLCTFVITVIFIIAIGIATVTINGNYTSNFRDFPKGIVTVTCFAFGYTNLVYPPDIFYGGEWLGILLYTIMGFVVKYMLINLIVSMMRDQMASVKADRDKKVRQRITFWQFLRVEYAHFINYIVKVFHCQKGYQRKNRTVAQNIQRKLNSNELKRR---------------------------KTKISSIYSETIYVMPIDKDLEQMKY---------------RERIERTFTLAAILHTQMELMERLMFGD------EEGNLP-------SLDQEDEQVPETEED-------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "X2JI61-1", "uniprot_id": "X2JI61_DROME", "id": "X2JI61-1", "name": "", "aln": "----------------------------------------------------------------MKVKKTHWAMFAITVGIIIGCMICIA-VFAGFQHEDVKFKTMLVSIVIVLIFQFLIGDPIKFVILSIDRALWPPRIYIPPRCDKDEMDE----KEERRDFLKQRLIN----------------------------------------KRANLMLTSRYRNYKLN---DQYKMIAHDLFIYGPYFLCLMCLVLVTRDQTLYHNTRIITDLF----MYN-HTDYTGLQEVYFLNQLFDFIESTLVL------AFNSNSTE--------------------------------------------------------------------------------------------------SGSPGWAHAEQSVLLGVMRLRQLRVSNPQVGLGPPKFSDTYYMPDWQLPYRKLHYSDKYWRIYEPWIPIKMGFEFLDALLMNFDHVGSLNSYPELAGYVSLLARSAANSMKVIDYLSENHWLTLNTSAVFIDFTLYNVDVNLFSICTLRVEKTPFGGIVPDVQVDSAKLLENVDQMPYTGLLALLIYVLVFIQFAQTLAVKLWYE-PHLLKS-VWNKLDLFIFMVNVLVVVLVVLRESLVASMMKKVEGASKMEFIDFRRPSRMHQLTTITIGFLICITTLRLWRVLQFASVFKLFTRTLYLAWSAVASTAIAIVIFLIGFCFAVVTINGNYSSNFNKLVKSMVMCMCYSFGFSAQVKPSELFHGGKWLGILCYGVLAFVIIVLLINVFVSLINDYFTVAKTIRDSERENRITFFEFLVVEFSGVLGRFRKLPCWRRNYVRNGRTVAENVSRKLDSMDRQR----------------------------LMRRRLRQGRHHVSRPVSAEDALLEY---------------KDRGDKMVNVHYILNIQLTLIRMFLFDEYVEWPQEQQKQPEAQDPDPNLGPDGSPPQDKRQDEAEA---------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VK95-1", "uniprot_id": "Q9VK95_DROME", "id": "Q9VK95-1", "name": "", "aln": "MAQQGQSGRSPSGPPGPPPPRPPKTPPGASPRGTPTADSTPGDVTPARGPPPPPATKRVSIGVGSTRSAPPPATDPTGPPPTAGKPVRDTGPSTSPRPSLRDPGQSTSDKPSTSDKPSTSDKPSTSARTTVREPGPSSSPSRPVSTRESGRITFQEAAPSTSAKVVKLAASEPRPAKPPEKEGFSLFKRKKKSVGSSTPPSPSRGHRAPSIIAASALQNRAKTNRILYTTDEEVREALVEFSVFIIFLILTSLVVLSVRHTYMFYFNDTMKKLFTNREMVVAPSVTVGFEKLITVPDWWDYLKYNFLVTLHGDLTFMDDAQANLTSMPPEGSEQGSEQGSEQGSEQSPEEVVGEAPEEAPEMDRLQEDFKYNGNPYIDLRGHRRAKRQSGVDGNSEDGSEDVSGNYLKDDSDSIQANMSFHHLEGRVFLYENLLLGPPRLRQIRVRKE------SCYVNDAFIRYFNTCYAAYSSGAEDRKPMHKGSPFRTMHDLDS-----TPIWTVLAFYRT-GGYTVNLDYDKDRNVKIINDLKDIHWLDRGSRLCLVEFNLFNENTDIFQSIKLIAEIPPTGGVIPQAHLQTVKMYSFFTDRSMLMTVIYIFWYIMVIYYTIYEITEIRKSGIKIYFCSMLNILDCAILLGCYLALVYNIWHSFKVMSLTARAHSD--VTYQSLDVLCFWNIIYVDMMAILAFLVWIKIFKFISFNKTLVQFTTTLKRCSKDLAGFSLMFGIVFLAYAQLGLLLFGTKHPDFRNFITSILTMIRMILGDFQYN---LIEQANRVLGPIYFLTYILLVFFILLNMFLAIIMETYNTVKGEITQG---RSHLGSYIYRKLSGMLYWITHCGRKRRHHPQASETEDKDAEHDVGAA-------------------------------HDETHEIRKNMTPAEQQYFKDIPQGEN-----------------------QDMVRLNNRVGLLEEILEKLINNMDDILKRVEKDYHNKKK---------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . . : . . : * : : :: : :: :. :. . ** .: : : : : : :: : . . *** *:**::. . . : : : . : * *: * . : * . ** .: :::*. :* : : * * .* . :: : .: . ..: : : : :. : :* :. :. : * : : .: . .. :. ::::: :.* .: :: *: . : : *.::. : *. * : . :. :* : ... ** : :.: :*:*:::::: : .* . : . : : : : : . . : * :: :. : . ", "identical_positions": 34, "similar_positions": 147, "identity": "3.19%" }, { "cls_id": "homologset.agr.MGI:1352449", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P18340-1", "uniprot_id": "CXCL9_MOUSE", "id": "P18340-1", "name": "C-X-C motif chemokine 9", "aln": "-MKSAVLFLLGIIFLEQCGVRGTLVIRNARCSCISTSRGTIHYKSLKDLKQFAPSPNCNKTEIIATLKNGD-QTCLDPDSANVK-KLMKEWEKKISQKKKQKRGKKHQKNMKNRKPKTPQSRRRSRKTT", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8K4B1-1", "uniprot_id": "Q8K4B1_RAT", "id": "Q8K4B1-1", "name": "C-X-C motif chemokine", "aln": "-MKSVALFLMGIIFLDHCGVRGTLVIRNQRCSCISTSQGTFHYKSLKDLKQFAPSPNCNKTEIIATLKNGD-QTCLDPDSARVK-KLMKEWEKKISQKKKQKRGKNHQRSKKTRKAKTPHHPE-SKKTA", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q07325-1", "uniprot_id": "CXCL9_HUMAN", "id": "Q07325-1", "name": "C-X-C motif chemokine 9", "aln": "MKKSGVLFLLGIILLVLIGVQGTPVVRKGRCSCISTNQGTIHLQSLKDLKQFAPSPSCEKIEIIATLKNGV-QTCLNPDSADVK-ELIKKWEKQVSQKKKQKNGKKHQKKKVLKVRKSQRSRQ--KKTT", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "B0R191-1", "uniprot_id": "CX116_DANRE", "id": "B0R191-1", "name": "C-X-C motif chemokine 11-6", "aln": "-MKTLAAFLL-LSCLIAGEVNGQDRSSRARCFCVDKGLNMVLLKNLDKVEIFPPSPSCNKHEIVVTLKNGAGQKCLNPDSKFTKNVVLKAIGKRMQQSVPHSTTTGTVKSSMTSSTSAPTAFK------", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *: . **: : * *.* . ** *:... . . :.*..:: *.***.*:* **:.***** *.**:*** .* ::* *::.*. :. . :. .: . ", "identical_positions": 33, "similar_positions": 40, "identity": "25.58%" }, { "cls_id": "homologset.agr.MGI:1352450", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P17515-1", "uniprot_id": "CXL10_MOUSE", "id": "P17515-1", "name": "C-X-C motif chemokine 10", "aln": "MNPSAAVIFCLILLGLSGTQGIPLARTVRCNCIHIDDGPVRMRAIGKLEIIPASLSCPRVEIIATMKKNDEQRCLNPESKTIKNLMKAFSQKRSKRAP", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P48973-1", "uniprot_id": "CXL10_RAT", "id": "P48973-1", "name": "C-X-C motif chemokine 10", "aln": "MNPSAAVVLCLVLLSLSGTQGIPLARTVRCTCIDFHEQPLRPRAIGKLEIIPASLSCPHVEIIATMKKNNEKRCLNPESEAIKSLLKAVSQRRSKRAP", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P02778-1", "uniprot_id": "CXL10_HUMAN", "id": "P02778-1", "name": "C-X-C motif chemokine 10", "aln": "MNQTAILICCLIFLTLSGIQGVPLSRTVRCTCISISNQPVNPRSLEKLEIIPASQFCPRVEIIATMKKKGEKRCLNPESKAIKNLLKAVSKERSKRSP", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "** :* :: **::* *** **:**:*****.** : : *:. *:: ******** **:*********:.*:*******::**.*:**.*:.****:*", "identical_positions": 60, "similar_positions": 26, "identity": "61.22%" }, { "cls_id": "homologset.agr.MGI:1352451", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P10589-1", "uniprot_id": "COT1_HUMAN", "id": "P10589-1", "name": "COUP transcription factor 1", "aln": "--------------------------------MAMVV---SSWRDP--------------------------------------------------------------QDDVAGGNPGGPNPAAQAARGGGGGAGEQQQQAGSGAPHTPQTPGQ------------PGAPATPGT-----AGDKGQGPPGSGQSQQHIECVVCGDKSSGKHYGQFTCEGCKSFFKRSVRRNLTYTCRANRNCPIDQHHRNQCQYCRLKKCLKVGMRREAVQRGRMPPTQP----NPGQYALTNGDPL-----NGHCYLSGYISLLLRAEPYPTSRYGSQCMQPNNIMGIENICELAARLLFSAVEWARNIPFFPDLQITDQVSLLRLTWSELFVLNAAQCSMPLHVAPLLAAAGLHASPMSADRVVAFMDHIRIFQEQVEKLKALHVDSAEYSCLKAIVLFTS------------------------------DACGLSDAAHIESLQEKSQ-----------------------CALEEYVRSQYPNQ--------------------------------------------PSRFG----------KLLLRLPSLRTVSSS----------------------------VIEQLFFVRLVGKTPIETLIRDMLLSGSSFNWPYMSIQCS------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q60632-1", "uniprot_id": "COT1_MOUSE", "id": "Q60632-1", "name": "COUP transcription factor 1", "aln": "--------------------------------MAMVV---SSWRDP--------------------------------------------------------------QDDVAGGNPGGPNPAAQAARGGGGGAGEQQQ-AGSGAPHTPQTPGQ------------PGAPATPGT-----QGDKGQGPPGSGQSQQHIECVVCGDKSSGKHYGQFTCEGCKSFFKRSVRRNLTYTCRANRNCPIDQHHRNQCQYCRLKKCLKVGMRREAVQRGRMPPTQP----NPGQYALTNGDPL-----NGHCYLSGYISLLLRAEPYPTSRYGSQCMQPNNIMGIENICELAARLLFSAVEWARNIPFFPDLQITDQVSLLRLTWSELFVLNAAQCSMPLHVAPLLAAAGLHASPMSADRVVAFMDHIRIFQEQVEKLKALHVDSAEYSCLKAIVLFTS------------------------------DACGLSDAAHIESLQEKSQ-----------------------CALEEYVRSQYPNQ--------------------------------------------PSRFG----------KLLLRLPSLRTVSSS----------------------------VIEQLFFVRLVGKTPIETLIRDMLLSGSSFNWPYMSIQCS------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q06725-1", "uniprot_id": "N2F1A_DANRE", "id": "Q06725-1", "name": "Nuclear receptor subfamily 2 group F member 1-A", "aln": "--------------------------------MAMVV---SVWRDP--------------------------------------------------------------QEDVAGGPPSGPNPAAQPAR-------EQQQ-AASAAPHTPQTPSQ------------PGPPSTPGT-----AGDKG--SQNSGQSQQHIECVVCGDKSSGKHYGQFTCEGCKSFFKRSVRRNLTYTCRANRNCPIDQHHRNQCQYCRLKKCLKVGMRREAVQRGRMPPTQP----NPGQYALTNGDPL-----NGHCYLSGYISLLLRAEPYPTSRYGSQCMQPNNIMGIENICELAARLLFSAVEWARNIPFFPDLQITDQVSLLRLTWSELFVLNAAQCSMPLHVAPLLAAAGLHASPMSADRVVAFMDHIRIFQEQVEKLKALHVDSAEYSCIKAIVLFTS------------------------------DACGLSDAAHIESLQEKSQ-----------------------CALEEYVRSQYPNQ--------------------------------------------PSRFG----------KLLLRLPSLRTVSSS----------------------------VIEQLFFVRLVGKTPIETLIRDMLLSGSSFNWPYMSIQ--------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q6PH18-1", "uniprot_id": "N2F1B_DANRE", "id": "Q6PH18-1", "name": "Nuclear receptor subfamily 2 group F member 1-B", "aln": "--------------------------------MAMVV---SAWRDP--------------------------------------------------------------QEELAAVD---------------------DQ-SAAGREHLQHR-------------------HSPKS-----AEEKA---QIAAQNQQHVECVVCGDKSSGKHYGQFTCEGCKSFFKRSVRRNLSYTCRANRNCPVDQHHRNQCQYCRLKKCLKVGMRREAVQRGRMPPNQP----NPSHYALTNGDHL-----NGQCYLSGYISLLLRAEPYPASRYGNQCMQSGNIMGIENICELAARLLFSAVEWARNIPFFPDLQITDQVSLLRLTWSELFVLNAAQSSMPLHVAPLLAAAGLHASPMSADRVVAFMDHIRFFQEQVEKLKALQVDSAEYSCAKAIVLFTS------------------------------DACGLSDIPHIEGLQEKSQ-----------------------CALEEYVRSQYPNQ--------------------------------------------PTRFG----------KLLLRLPALRMVSSS----------------------------VIEQLFFVRLVGKTPIETLIRDMLLSGSSFNWPYMPIQ--------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "O09018-1", "uniprot_id": "COT2_RAT", "id": "O09018-1", "name": "COUP transcription factor 2", "aln": "--------------------------------MAMVV---STWRDP--------------------------------------------------------------QDEVPGSQGSQASQAPPVPG------------PPPGAPHTPQTPGQ------------GGPASTPAQTAAGSQGGPGGPGSDKQQQQQHIECVVCGDKSSGKHYGQFTCEGCKSFFKRSVRRNLSYTCRANRNCPIDQHHRNQCQYCRLKKCLKVGMRREAVQRGRMPPTQP----THGQFALTNGDPL-----NCHSYLSGYISLLLRAEPYPTSRFGSQCMQPNNIMGIENICELAARMLFSAVEWARNIPFFPDLQITDQVALLRLTWSELFVLNAAQCSMPLHVAPLLAAAGLHASPMSADRVVAFMDHIRIFQEQVEKLKALHVDSAEYSCLKAIVLFTS------------------------------DACGLSDVAHVESLQEKSQ-----------------------CALEEYVRSQYPNQ--------------------------------------------PTRFG----------KLLLRLPSLRTVSSS----------------------------VIEQLFFVRLVGKTPIETLIRDMLLSGSSFNWPYMAIQ--------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P16376-1", "uniprot_id": "7UP2_DROME", "id": "P16376-1", "name": "Steroid receptor seven-up, isoform A", "aln": "MCASPSTAPGFFNPRPQSGAELSAFDIGLSRSMGLGVPPHSAWHEPPASLGGHLHAASAGPGTTTGSVATGGGGTTPSSVASQQSAVIKQDLSCPSLNQAGSGHHPGIKEDLSSSLPSANGGSAGGHHSGSGSGSGSGVNPGHGSDMLPLIKGHGQDMLTSIKGQPTGCGSTTPSSQANSSHSQSSNSGSQIDSKQNIECVVCGDKSSGKHYGQFTCEGCKSFFKRSVRRNLTYSCRGSRNCPIDQHHRNQCQYCRLKKCLKMGMRREAVQRGRVPPTQPGLAGMHGQYQIANGDPMGIAGFNGHSYLSSYISLLLRAEPYPTSRYG-QCMQPNNIMGIDNICELAARLLFSAVEWAKNIPFFPELQVTDQVALLRLVWSELFVLNASQCSMPLHVAPLLAAAGLHASPMAADRVVAFMDHIRIFQEQVEKLKALHVDSAEYSCLKAIVLFTTGKLLDILYKDVPALLTKVSALLGKGSTASNDDVLAVVRDHLDELNRQEQESQAQQQAPLHLAAFMNCVAGVEAAVQQAEQAQVPTSSASASVSAPLVPSAGSAFSSCQAKSAGSEMDLLASLYAQAQATPPSSGGGDASGHNNSSGLGASLPTQSQSGSSSRNLTASPLSTSLATAPAPASASAPAPVPTSSVAQVPVPAPVPVTSSASSSSLGGGAYQTPSAAAAAAAMFHYQTPPRAAFGSAFDMFHHSTPFGVGVGHAHALAHSSGSGSASFGSPSYRYSPYSLAGSRWQL", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *.: * * *::* ::::.. . . :. . :.:*::**********************************:*:**..****:******************:***********:**.** .:: ::*** : * :.***.************:**:* ****..*****:********:********:******:**:****:****.*********:*.********************:************:***********:******** *******: * *:: *:.:.* .*::: ::* *.. *: * * **: .** ..: * : . .*: : . *.*.::: * . ", "identical_positions": 230, "similar_positions": 86, "identity": "30.79%" }, { "cls_id": "homologset.agr.MGI:1352452", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P24468-1", "uniprot_id": "COT2_HUMAN", "id": "P24468-1", "name": "COUP transcription factor 2", "aln": "--------------------------------MAMVVS---TWRDPQD------------------------------EVPGSQGSQASQAP---PVPGPPPG---------APHTP-----------------------------------------QTPGQGGPASTPAQTAAGGQGGPGGPGSD---KQQQQQHIECVVCGDKSSGKHYGQFTCEGCKSFFKRSVRRNLSYTCRANRNCPIDQHHRNQCQYCRLKKCLKVGMRREA------VQRGRMPPTQP----THGQFALTNGDPL-----NCHSYLSGYISLLLRAEPYPTSRFGSQCMQPNNIMGIENICELAARMLFSAVEWARNIPFFPDLQITDQVALLRLTWSELFVLNAAQCSMPLHVAPLLAAAGLHASPMSADRVVAFMDHIRIFQEQVEKLKALHVDSAEYSCLKAIVLFTS-------------------DACGLSDVA-----------HVESLQEKSQ-----------------------CALEEYVRSQYP---------------------------------------------------------NQPTRFGKLLLRLP----SLRTVSSS---------------------VIEQLFFVRLVGKTPIETLIRDMLLSGSSFNWPYMAIQ--------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P43135-1", "uniprot_id": "COT2_MOUSE", "id": "P43135-1", "name": "COUP transcription factor 2", "aln": "--------------------------------MAMVVS---TWRDPQD------------------------------EVPGSQGSQASQAP---PVPGPPPG---------APHTP-----------------------------------------QTPGQGGPASTPAQTAAGGQGGPGGPGSD---KQQQQQHIECVVCGDKSSGKHYGQFTCEGCKSFFKRSVRRNLSYTCRANRNCPIDQHHRNQCQYCRLKKCLKVGMRREA------VQRGRMPPTQP----THGQFALTNGDPL-----NCHSYLSGYISLLLRAEPYPTSRFGSQCMQPNNIMGIENICELAARMLFSAVEWARNIPFFPDLQITDQVALLRLTWSELFVLNAAQCSMPLHVAPLLAAAGLHASPMSADRVVAFMDHIRIFQEQVEKLKALHVDSAEYSCLKAIVLFTS-------------------DACGLSDVA-----------HVESLQEKSQ-----------------------CALEEYVRSQYP---------------------------------------------------------NQPTRFGKLLLRLP----SLRTVSSS---------------------VIEQLFFVRLVGKTPIETLIRDMLLSGSSFNWPYMAIQ--------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O09018-1", "uniprot_id": "COT2_RAT", "id": "O09018-1", "name": "COUP transcription factor 2", "aln": "--------------------------------MAMVVS---TWRDPQD------------------------------EVPGSQGSQASQAP---PVPGPPPG---------APHTP-----------------------------------------QTPGQGGPASTPAQTAAGSQGGPGGPGSD---KQQQQQHIECVVCGDKSSGKHYGQFTCEGCKSFFKRSVRRNLSYTCRANRNCPIDQHHRNQCQYCRLKKCLKVGMRREA------VQRGRMPPTQP----THGQFALTNGDPL-----NCHSYLSGYISLLLRAEPYPTSRFGSQCMQPNNIMGIENICELAARMLFSAVEWARNIPFFPDLQITDQVALLRLTWSELFVLNAAQCSMPLHVAPLLAAAGLHASPMSADRVVAFMDHIRIFQEQVEKLKALHVDSAEYSCLKAIVLFTS-------------------DACGLSDVA-----------HVESLQEKSQ-----------------------CALEEYVRSQYP---------------------------------------------------------NQPTRFGKLLLRLP----SLRTVSSS---------------------VIEQLFFVRLVGKTPIETLIRDMLLSGSSFNWPYMAIQ--------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0AB32T5U5-1", "uniprot_id": "A0AB32T5U5_DANRE", "id": "A0AB32T5U5-1", "name": "", "aln": "--------------------------------MAMVV-----WRGSQD------------------------------DVAETHGTLSSQTQGGLSLPTPQPGQLGLTASQVAPPTP-----------------------------------------QTPVQG-PPNNNNNTQSTPTNQTTQSQSE---KQQPQ-HIECVVCGDKSSGKHYGQFTCEGCKSFFKRSVRRNLTYTCRANRNCPIDQHHRNQCQYCRLKKCLKVGMRREVSLFTAAVQRGRMPPTQP----HHGQFALTNGDPL-----HCHSYLSGYISLLLRAEPYPTSRYGSQCMQPNNIMGIENICELAARMLFSAVEWARNIPFFPDLQITDQVALLRLTWSELFVLNAAQCSMPLHVAPLLAAAGLHASPMSADRVVAFMDHIRIFQEQVEKLKALHVDSAEYSCLKAIVLFTS-------------------DACGLSDVA-----------HVESLQEKSQ-----------------------CALEEYVRSQYP---------------------------------------------------------NQPTRFGKLLLRLP----SLRTVSSS---------------------VIEQLFFVRLVGKTPIETLIRDMLLSGSSFNWPYMSIQ--------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P16376-1", "uniprot_id": "7UP2_DROME", "id": "P16376-1", "name": "Steroid receptor seven-up, isoform A", "aln": "MCASPSTAPGFFNPRPQSGAELSAFDIGLSRSMGLGVPPHSAWHEPPASLGGHLHAASAGPGTTTGSVATGGGGTTPSSVASQQSAVIKQDLSCPSLNQAGSGHHPGIKEDLSSSLPSANGGSAGGHHSGSGSGSGSGVNPGHGSDMLPLIKGHGQDMLTSIKGQPTGCGSTTPSSQANSSHSQSSNSGSQIDSKQNIECVVCGDKSSGKHYGQFTCEGCKSFFKRSVRRNLTYSCRGSRNCPIDQHHRNQCQYCRLKKCLKMGMRREA------VQRGRVPPTQPGLAGMHGQYQIANGDPMGIAGFNGHSYLSSYISLLLRAEPYPTSRYG-QCMQPNNIMGIDNICELAARLLFSAVEWAKNIPFFPELQVTDQVALLRLVWSELFVLNASQCSMPLHVAPLLAAAGLHASPMAADRVVAFMDHIRIFQEQVEKLKALHVDSAEYSCLKAIVLFTTGKLLDILYKDVPALLTKVSALLGKGSTASNDDVLAVVRDHLDELNRQEQESQAQQQAPLHLAAFMNCVAGVEAAVQQAEQAQVPTSSASASVSAPLVPSAGSAFSSCQAKSAGSEMDLLASLYAQAQATPPSSGGGDASGHNNSSGLGASLPTQSQSGSSSRNLTASPLSTSLATAPAPASASAPAPVPTSSVAQVPVPAPVPVTSSASSSSLGGGAYQTPSAAAAAAAMFHYQTPPRAAFGSAFDMFHHSTPFGVGVGHAHALAHSSGSGSASFGSPSYRYSPYSLAGSRWQL", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *.: * *: . .*. :.: .* .: . .* :. * *. :* *.. * : . . *: : : : :***********************************:*:**..***********************:*****. *****:***** ***: ::****: : *****.***************:* ***********:********:********:******:**:*********.*********:**********************:*****************************************: * ...* *::.*:.:.* .*::: ::* * *:.: :* * . * *.:::* ..: * : . .*: : . *.*.::: * : ", "identical_positions": 251, "similar_positions": 91, "identity": "33.33%" }, { "cls_id": "homologset.agr.MGI:1352453", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O09017-1", "uniprot_id": "NR2F6_RAT", "id": "O09017-1", "name": "Nuclear receptor subfamily 2 group F member 6", "aln": "------------------------------------------------------------MAMVTGGWGGPGGDTN-------------------GVDKAGGSYPRATEDDSASPP-----------------GATSDAEPGD-----------------------------------------EERPGLQVD------CVVCGDKSSGKHYGVFTCEGCKSFFKRTIRRNLSYTCRSNRDCQIDQHHRNQCQYCRLKKCFRVGMRKEA-----VQPGPIPHALPGPAACS---PPG------AAGVEPFAGPP-VSELIAQLLRAEPYP------AAG-RFGGGG----AVLGIDNVCELAARLLFSTVEWARHAPFFPELPAADQVGLLRLSWSELFVLNAAQAPVPLHTAPLLAAAGLHAGPMAAERAVAFMDQVRAFQEQVDKLGRLQVDAAEYGCLKAIALFTP-------------------DACGLSDPAHVESLQEKAQVALTEYVRAQYPSQPQRFGRLLLR-------------------------------------------------------------------------------------------------------------------LPALRAVPASL-ISQLFFMRLVGKTPIETLIRDMLLSGSTFNWPYGSG---------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P43136-1", "uniprot_id": "NR2F6_MOUSE", "id": "P43136-1", "name": "Nuclear receptor subfamily 2 group F member 6", "aln": "------------------------------------------------------------MAMVTGGWGDPGGDTN-------------------GVDKAGGSYPRATEDDSASPP-----------------GATSDAEPGD-----------------------------------------EERPGLQVD------CVVCGDKSSGKHYGVFTCEGCKSFFKRSIRRNLSYTCRSNRDCQIDQHHRNQCQYCRLKKCFRVGMRKEA-----VQRGRIPHALPGPAACS---PPG------ATGVEPFTGPP-VSELIAQLLRAEPYP------AAG-RFGGGG----AVLGIDNVCELAARLLFSTVEWARHAPFFPELPAADQVALLRLSWSELFVLNAAQAALPLHTAPLLAAAGLHAAPMAAERAVAFMDQVRAFQEQVDKLGRLQVDAAEYGCLKAIALFTP-------------------DACGLSDPAHVESLQEKAQVALTEYVRAQYPSQPQRFGRLLLR-------------------------------------------------------------------------------------------------------------------LPALRAVPASL-ISQLFFMRLVGKTPIETLIRDMLLSGSTFNWPYGSG---------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P10588-1", "uniprot_id": "NR2F6_HUMAN", "id": "P10588-1", "name": "Nuclear receptor subfamily 2 group F member 6", "aln": "------------------------------------------------------------MAMVTGGWGGPGGDTN-------------------GVDKAGG-YPRAAEDDSASPP-----------------GAASDAEPGD-----------------------------------------EERPGLQVD------CVVCGDKSSGKHYGVFTCEGCKSFFKRSIRRNLSYTCRSNRDCQIDQHHRNQCQYCRLKKCFRVGMRKEA-----VQRGRIPHSLPGAVAASSGSPPGSALAAVASGGDLFPGQP-VSELIAQLLRAEPYP------AAAGRFGAGGGAAGAVLGIDNVCELAARLLFSTVEWARHAPFFPELPVADQVALLRLSWSELFVLNAAQAALPLHTAPLLAAAGLHAAPMAAERAVAFMDQVRAFQEQVDKLGRLQVDSAEYGCLKAIALFTP-------------------DACGLSDPAHVESLQEKAQVALTEYVRAQYPSQPQRFGRLLLR-------------------------------------------------------------------------------------------------------------------LPALRAVPASL-ISQLFFMRLVGKTPIETLIRDMLLSGSTFNWPYGSGQ--------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9Q751-1", "uniprot_id": "A0A8M9Q751_DANRE", "id": "A0A8M9Q751-1", "name": "Nuclear receptor subfamily 2 group F member 6", "aln": "------------------------------------------------------------MAMVSGGWANPNGSAN-------------------GLGEKG--YLRG-EEEGSSPQ-----------------AGNSDVEGGE-----------------------------------------EDK-ACVVD------CVVCGDKSSGKHYGVFTCEGCKSFFKRSIRRNLNYTCRSNRECQIDQHHRNQCQYCRLKKCFRVGMRKEGQQTPTVQRGRIPPSHAGISPASMVGAGGDVGGGPGMGADFFNGQP-VSELISQLLRAEPYPNSRYGAQCGQQLQGAN---SSMMGIDNICELAARLLFSTIEWARNIPYFPDLPVSEQVALLRLSWSELFILNAAQSALPLHTAPLLAAAGFHSSPMPADRVVSFMDQVRVFQDQVDKLTRLQVDSVEYSCLKAIALFSP-------------------DACGLSDPAHVESLQEKAQVALTEYERMQYPGQPQRFGRLLLR-------------------------------------------------------------------------------------------------------------------LPALRAVPANL-ISQLFFMRLVGKTPIETLIRDMQLSGSSISWPYVPGQ--------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P16376-1", "uniprot_id": "7UP2_DROME", "id": "P16376-1", "name": "Steroid receptor seven-up, isoform A", "aln": "MCASPSTAPGFFNPRPQSGAELSAFDIGLSRSMGLGVPPHSAWHEPPASLGGHLHAASAGPGTTTGSVATGGGGTTPSSVASQQSAVIKQDLSCPSLNQAGSGHHPGIKEDLSSSLPSANGGSAGGHHSGSGSGSGSGVNPGHGSDMLPLIKGHGQDMLTSIKGQPTGCGSTTPSSQANSSHSQSSNSGSQIDSKQNIECVVCGDKSSGKHYGQFTCEGCKSFFKRSVRRNLTYSCRGSRNCPIDQHHRNQCQYCRLKKCLKMGMRREA-----VQRGRVPPTQPGLAGMHGQYQIAN---GDPMGIAGFNGHSYLSSYISLLLRAEPYPTS----RYGQCMQPNN-----IMGIDNICELAARLLFSAVEWAKNIPFFPELQVTDQVALLRLVWSELFVLNASQCSMPLHVAPLLAAAGLHASPMAADRVVAFMDHIRIFQEQVEKLKALHVDSAEYSCLKAIVLFTTGKLLDILYKDVPALLTKVSALLGKGSTASNDDVLAVVRDHLDELNRQEQESQAQQQAPLHLAAFMNCVAGVEAAVQQAEQAQVPTSSASASVSAPLVPSAGSAFSSCQAKSAGSEMDLLASLYAQAQATPPSSGGGDASGHNNSSGLGASLPTQSQSGSSSRNLTASPLSTSLATAPAPASASAPAPVPTSSVAQVPVPAPVPVTSSASSSSLGGGAYQTPSAAAAAAAMFHYQTPPRAAFGSAFDMFHHSTPFGVGVGHAHALAHSSGSGSASFGSPSYRYSPYSLAGSRWQL", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . .:*. . .*.:. .:.: * : . ::: :*. .. *..: *. ... . :* ************** ************::****.*:**..*:* *****************:::***:*. ** * :* : .* . * * * . :*. *: ******** . : . ::****:**********::***:: *:**:* .::**.**** *****:***:*..:***.********:*:.**.*:*.*:***::* **:**:** *:**:.**.*****.**:. * ...* :.: .: * * * : .*.*: . * * ** :.** : *.: : : . .*: : . *.*.: . * .. ", "identical_positions": 174, "similar_positions": 122, "identity": "22.8%" }, { "cls_id": "homologset.agr.MGI:1352454", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P22829-1", "uniprot_id": "NR4A1_RAT", "id": "P22829-1", "name": "Nuclear receptor subfamily 4 group A member 1", "aln": "-------------------------------------------------------------------------------------------------------------MPCIQAQYG---------TPATSPGPRDHLTG-------------------------------------------DPLALEFSKPTMDLASPETAPTAPATLPSFSTFMDGGYTGEFDTFLYQLPGT---------AQPCS--------------SASSTSSSSSSAT-----------------------------------------------SPASASFKFEDFQVYG---------------------------------------CYPG----------------------TLSGPLDETLSS------------SGSD-------------------------------------YYGSPCSAPSPPTPNFQPSQLSPWDGSFG------------HFSPSQTYEGLRVWTEQLPKAS----GPPPPP------------------------------------------TFFSFSPPTGPSPSLAQSSLKLFP--APATHQLGE------------------GESYSVP--AAFPGLAPTSPNCDTSGILDA-----------PVTSTKARSGSSGGS-----------------------------------------------EGRCAVCGDNASCQHYGVRTCEGCKGFFKRTVQKSAKYICLANKDCPVDKRRRNRCQFCRFQKCLAVGMVKEVVRTDSLKGRRGRLPSKPKQP---PDASPTNLLTSLIRAHLDSGPNTAKLDYSKFQELVLPRFGKEDAGDVQQFYDLLSGSLDVIRKWAEKIPGFIELSPGDQDLLLESAFLELFILRLAYRSKPGEGKLIFCSGLVLHRLQCARGFGDWIDNILAFSRSLHSLGVDVPAFACLSALVLITDRHGLQDPRRVEELQNRIASCLKEHMAAVAGDPQPASCLSRLLGKLPELRTLCTQGLQRIFCLKLEDLVPPPPIVDKIFMDTLSF", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P12813-1", "uniprot_id": "NR4A1_MOUSE", "id": "P12813-1", "name": "Nuclear receptor subfamily 4 group A member 1", "aln": "-------------------------------------------------------------------------------------------------------------MPCIQAQYG---------TPATSPGPRDHLTG-------------------------------------------DPLALEFGKPTMDLASPETAPAAPATLPSFSTFMDG-YTGEFDTFLYQLPGT---------TQPCSSAC----------SSASSTSSSSSSAT-----------------------------------------------SPASASFKFEDFQVYG---------------------------------------CYPG----------------------TLSGPLDETLSS------------SGSE-------------------------------------YYGSPCSAPSPSTPNFQPSQLSPWDGSFG------------HFSPSQTYEGLWAWTEQLPKASS---GPPPPP------------------------------------------TFFSFSPPTGPSPSLAQSSLKLFP--PPATHQLGE------------------GESYSMP--AAFPGLAPTSPNRDTSGILDA-----------PVTSTKSRSGASGGS-----------------------------------------------EGRCAVCGDNASCQHYGVRTCEGCKGFFKRTVQKSAKYICLANKDCPVDKRRRNRCQFCRFQKCLAVGMVKEVVRTDSLKGRRGRLPSKPKQP---PDASPTNLLTSLIRAHLDSGPSTAKLDYSKFQELVLPRFGKEDAGDVQQFYDLLSGSLDVIRKWAEKIPGFIELCPGDQDLLLESAFLELFILRLAYRSKPGEGKLIFCSGLVLHQLQCARGFGDWIDNILAFSRSLHSLGVDVPAFACLSALVLITDRHGLQDPRRVEELQNRIASCLKEHMATVAGDPQPASCLSRLLGKLPELRTLCTQGLQRIFCLKLEDLVPPPPIVDKIFMDTLSF", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P22736-1", "uniprot_id": "NR4A1_HUMAN", "id": "P22736-1", "name": "Nuclear receptor subfamily 4immunitygroup A member 1", "aln": "-------------------------------------------------------------------------------------------------------------MPCIQAQYG---------TPAPSPGPRDHLAS-------------------------------------------DPLTPEFIKPTMDLASPEAAPAAPTALPSFSTFMDG-YTGEFDTFLYQLPGT---------VQPCSS------------ASSSASSTSSSSAT-----------------------------------------------SPASASFKFEDFQVYG---------------------------------------CYPG----------------------PLSGPVDEALSS------------SGSD-------------------------------------YYGSPCSAPSPSTPSFQPPQLSPWDGSFG------------HFSPSQTYEGLRAWTEQLPKAS----GPPQPP------------------------------------------AFFSFSPPTGPSPSLAQSPLKLFP--SQATHQLGE------------------GESYSMP--TAFPGLAPTSPHLEGSGILDT-----------PVTSTKARSGAPGGS-----------------------------------------------EGRCAVCGDNASCQHYGVRTCEGCKGFFKRTVQKNAKYICLANKDCPVDKRRRNRCQFCRFQKCLAVGMVKEVVRTDSLKGRRGRLPSKPKQP---PDASPANLLTSLVRAHLDSGPSTAKLDYSKFQELVLPHFGKEDAGDVQQFYDLLSGSLEVIRKWAEKIPGFAELSPADQDLLLESAFLELFILRLAYRSKPGEGKLIFCSGLVLHRLQCARGFGDWIDSILAFSRSLHSLLVDVPAFACLSALVLITDRHGLQEPRRVEELQNRIASCLKEHVAAVAGEPQPASCLSRLLGKLPELRTLCTQGLQRIFYLKLEDLVPPPPIIDKIFMDTLPF", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P49869-1", "uniprot_id": "HR38_DROME", "id": "P49869-1", "name": "Probable nuclear hormone receptor HR38", "aln": "MMRDRLASLIVVKQEGGSNTSISHHQATAIKCEASLYTESSLFQEINNNSCYRQNLNAPTHQQSHTSHLQHAQQHQTHQQHPLLPPPLPTLPLIYPCRNLFPDGCDINHLACCSSSNSNSNCNSDSNSTSSSPGNSHFFANGNTCAAALTPAPPATEPRKIKPLGAGKLKVGKTDSNSDSNSNCDSRAAAAASTSATSATSATTLAATAAATAAAAEAGGAASAAAAAKISQVRLTNQATTSMLLLQPNSSFSSLSPFDNFSTQTASTTTTTSASAAGHHQHHNHLLHQQHHNQQQQQQQQQQQQQQQQQQQEHLQQQHQQQLVSPQQHLLKSETLLSHEEDQLISNLTDSSVVSHSELFSDLFFPSDSNNSLLSPTTSGYPDNPAEDLTSSIENLTKLTCLRDKRLSSIPEQQLSSEQEQQLCLLSLRSSSDPAIALHAQQQQQQQQQQQQQQQQHQQQQQHLQLQLISPIGGPLSCGS-SLPSFQETYSLKYNSSSGSSPQQASSSSTAAPTPTDQVLTLKMDEDCFPPLSGGWSASPPAPSQLQQLHTLQSQAQMSHPNSSNNSSNNAGNSHNNSGGYNYHGHFNAINASANLSPSSSASSLYEYNGVSAADNFYGQQQQQQQQSYQQHNYNSHNGERYSLPTFPTISELAAATAAVEAAAAATVGGPPPVRRASLPVQRTVSPAGSTAQSPKLAKITLNQRHSHAHAHALQLNSAPNSAASSPASADLQAGRLLQAPSQLCAVCGDTAACQHYGVRTCEGCKGFFKRTVQKGSKYVCLADKNCPVDKRRRNRCQFCRFQKCLVVGMVKEVVRTDSLKGRRGRLPSKPKSPQESPPSPPISLITALVRSHVDTTPDPSCLDYSHYEEQSMS-----EADKVQQFYQLLTSSVDVIKQFAEKIPGYFDLLPEDQELLFQSASLELFVLRLAYRARIDDTKLIFCNGTVLHRTQCLRSFGEWLNDIMEFSRSLHNLEIDISAFACLCALTLITERHGLREPKKVEQLQMKIIGSLRDHVTYNAEAQKKQHYFSRLLGKLPELRSLSVQGLQRIFYLKLEDLVPAPALIENMFVTTLPF", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :.* .:. . :.:.*** ..::. *. : ..: *:. :: :*.:: .: :: .* :. : : *: * ** * ::*:::::*:**: ** . :* * : : **. **. :: *** *.*: *.* *. * . *.** . ::.* * :*:: * : :* * ..* .* * ::...:. *** : *.* : . * : *: ** **:* .::. **.::. : :. . ** * : :*:.. * . ******.*:**********************.:**:***:*:********************.*************************.* * :.* .*:*:*:*:*:*: *..: ****:::* :. :*..*****:**:.*::**:::******: :* * **:**::** ****:******:: .: *****.* ***: ** *.**:*::.*: ******.* :*:.*****.**.***:****::*::**:** :* ..*::*:: * : :***********:*..******* ********.*.:::::*: **.*", "identical_positions": 274, "similar_positions": 193, "identity": "25.39%" }, { "cls_id": "homologset.agr.MGI:1352456", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q07917-1", "uniprot_id": "NR4A2_RAT", "id": "Q07917-1", "name": "Nuclear receptor subfamily 4 group A member 2", "aln": "-------------------------------------------------------------------------------------------------------------MPCVQAQYGSSPQGASPASQSYS-----YHSSGEYSSDFLTPEFVKFS---------------------------------------------------------------------------MDLTNTEIT-ATTSLP--SFSTF--MDNYSTG---------------YDVKPPCLYQMPLSGQQSSIKVEDIQMHNYQQHSHLPPQSEEMMPHSGSVYYKPSSPPTPS--------TPGFQVQHSPMWDD-----------------------PGSLHNFHQNYVATTHMIEQRKTPVS----------RLSLFSFKQS---------------------------------------RPGTPVSS--CQMRFDGPLHVPMNPEPAGSHHVVDGQTFAVPNP------------------------------------IRKPASMGFPG-------------------------------------------------------------------------------------------------------------------------------------------------LQIGHASQLLDTQVPSPPSRGSPSNEG---------LCAVCGDNAACQHYGVRTCEGCKGFFKRTVQKNAKYVCLANKNCPVDKRRRNRCQYCRFQKCLAVGMVKEVVRTDSLKGRRGRLPSKPKSPQDPSPPSPPVSLISALVRAHVDSNPAMTSLDYSRFQANPDYQMSGDDTQHIQQFYDLLTGSMEIIRGWAEKIPGFADLPKADQDLLFESAFLELFVLRLAYRSNPVEGKLIFCNGVVLHRLQCVRGFGEWIDSIVEFSSNLQNMNIDISAFSCIAALAMVTERHGLKEPKRVEELQNKIVNCLKDHVTFNNGGLNRPNYLSKLLGKLPELRTLCTQGLQRIFYLKLEDLVPPPAIIDKLFLDTLPF", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q06219-1", "uniprot_id": "NR4A2_MOUSE", "id": "Q06219-1", "name": "Nuclear receptor subfamily 4 group A member 2", "aln": "-------------------------------------------------------------------------------------------------------------MPCVQAQYGSSPQGASPASQSYS-----YHSSGEYSSDFLTPEFVKFS---------------------------------------------------------------------------MDLTNTEIT-ATTSLP--SFSTF--MDNYSTG---------------YDVKPPCLYQMPLSGQQSSIKVEDIQMHNYQQHSHLPPQSEEMMPHSGSVYYKPSSPPTPS--------TPSFQVQHSPMWDD-----------------------PGSLHNFHQNYVATTHMIEQRKTPVS----------RLSLFSFKQS---------------------------------------PPGTPVSS--CQMRFDGPLHVPMNPEPAGSHHVVDGQTFAVPNP------------------------------------IRKPASMGFPG-------------------------------------------------------------------------------------------------------------------------------------------------LQIGHASQLLDTQVPSPPSRGSPSNEG---------LCAVCGDNAACQHYGVRTCEGCKGFFKRTVQKNAKYVCLANKNCPVDKRRRNRCQYCRFQKCLAVGMVKEVVRTDSLKGRRGRLPSKPKSPQDPSPPSPPVSLISALVRAHVDSNPAMTSLDYSRFQANPDYQMSGDDTQHIQQFYDLLTGSMEIIRGWAEKIPGFADLPKADQDLLFESAFLELFVLRLAYRSNPVEGKLIFCNGVVLHRLQCVRGFGEWIDSIVEFSSNLQNMNIDISAFSCIAALAMVTERHGLKEPKRVEELQNKIVNCLKDHVTFNNGGLNRPNYLSKLLGKLPELRTLCTQGLQRIFYLKLEDLVPPPAIIDKLFLDTLPF", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P43354-1", "uniprot_id": "NR4A2_HUMAN", "id": "P43354-1", "name": "Nuclear receptor subfamily 4 group A member 2", "aln": "-------------------------------------------------------------------------------------------------------------MPCVQAQYGSSPQGASPASQSYS-----YHSSGEYSSDFLTPEFVKFS---------------------------------------------------------------------------MDLTNTEIT-ATTSLP--SFSTF--MDNYSTG---------------YDVKPPCLYQMPLSGQQSSIKVEDIQMHNYQQHSHLPPQSEEMMPHSGSVYYKPSSPPTPT--------TPGFQVQHSPMWDD-----------------------PGSLHNFHQNYVATTHMIEQRKTPVS----------RLSLFSFKQS---------------------------------------PPGTPVSS--CQMRFDGPLHVPMNPEPAGSHHVVDGQTFAVPNP------------------------------------IRKPASMGFPG-------------------------------------------------------------------------------------------------------------------------------------------------LQIGHASQLLDTQVPSPPSRGSPSNEG---------LCAVCGDNAACQHYGVRTCEGCKGFFKRTVQKNAKYVCLANKNCPVDKRRRNRCQYCRFQKCLAVGMVKEVVRTDSLKGRRGRLPSKPKSPQEPSPPSPPVSLISALVRAHVDSNPAMTSLDYSRFQANPDYQMSGDDTQHIQQFYDLLTGSMEIIRGWAEKIPGFADLPKADQDLLFESAFLELFVLRLAYRSNPVEGKLIFCNGVVLHRLQCVRGFGEWIDSIVEFSSNLQNMNIDISAFSCIAALAMVTERHGLKEPKRVEELQNKIVNCLKDHVTFNNGGLNRPNYLSKLLGKLPELRTLCTQGLQRIFYLKLEDLVPPPAIIDKLFLDTLPF", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AA54CGF0-1", "uniprot_id": "A0AA54CGF0_DANRE", "id": "A0AA54CGF0-1", "name": "Nuclear receptor subfamily 4 group A member 2", "aln": "-------------------------------------------------------------------------------------------------------------MPCVQAQYGSSPQGASPASQSYS-----YHTSGEYSCDFLTPEFVKFS---------------------------------------------------------------------------MDLTNTEITAATTSLP--SFSTF--MDNYNTS---------------YDVKPPCLYQVPHSGEQSSIKVEDVQMHTYHQQSHLGPQSEEMMAHPGPMYFKPSSPHGPG--------PANFQVQPNHMWED-----------------------PGSLHTFHQNYMTS-HMIDQRKNPVS----------RLSLFSFKQS---------------------------------------PPGTPVSS--CQMRFDGPLHVSMH-DSTGAHRTLDSQSFAVPST------------------------------------IRKQAGIAFTHS------------------------------------------------------------------------------------------------------------------------------------------------LQLSHGHQLMDSQVPSPPSRGSPSNEG---------LCAVCGDNAACQHYGVRTCEGCKGFFKRTVQKNAKYVCLANKNCPVDKRRRNRCQYCRFQKCLVVGMVKEVVRTDNLKGRRGRLPSKPKSPQESSPPSPPVSLISALVRAHVDSNPSMNSLDYTRFQANPDYQLSGDDTQHIQQFYDLLTGSMEIIRGWAEKIPGFTDLPKPDQDLLFESAFLELFVLRLAYRSNPMESKLIFCNGVVLHRLQCVRGFGEWIDSIVEFSSNLQNMNLDISAFSCIAALAMVTERHGLKEPKRVEDLQNKIVNCLKDQVTFNGGGLNRPNYLSKLLGKLPELRTLCTQGLQRIFYLKLEDLVPPPAIIDKLFLDTLPF", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P49869-1", "uniprot_id": "HR38_DROME", "id": "P49869-1", "name": "Probable nuclear hormone receptor HR38", "aln": "MMRDRLASLIVVKQEGGSNTSISHHQATAIKCEASLYTESSLFQEINNNSCYRQNLNAPTHQQSHTSHLQHAQQHQTHQQHPLLPPPLPTLPLIYPCRNLFPDGCDINHLACCSSSNSNSNCNSDSNSTSSSPGNSHFFANGNTCAAALTPAPPATEPRKIKPLGAGKLKVGKTDSNSDSNSNCDSRAAAAASTSATSATSATTLAATAAATAAAAEAGGAASAAAAAKISQVRLTNQATTSMLLLQPNSSFSSLSPFDNFSTQTASTTTTTSASAAGHHQHHNHLLHQQHHNQQQQQQQQQQQQQQQQQQQEHLQQQHQQQLVSPQQHLLKSETLLSHEEDQLISNLTDSSVVSHSELFSDLFFPSDSNNSLLSPTTSGYPDNPAEDLTSSIENLTKLTCLRDKRLSSIPEQQLSSEQEQQLCLLSLRSSSDPAIALHAQQQQQQQQQQQQQQQQHQQQQQHLQLQLISPIGGPLSCGSSLPSFQETYSLKYNSSSGSSPQQASSSSTAAPTPTDQVLTLKMDEDCFPPLSGGWSASPPAPSQLQQLHTLQSQAQMSHPNSSNNSSNNAGNSHNNSGGYNYHGHFNAINASANLSPSSSASSLYEYNGVSAADNFYGQQQQQQQQSYQQHNYNSHNGERYSLPTFPTISELAAATAAVEAAAAATVGGPPPVRRASLPVQRTVSPAGSTAQSPKLAKITLNQRHSHAHAHALQLNSAPNSAASSPASADLQAGRLLQAPSQLCAVCGDTAACQHYGVRTCEGCKGFFKRTVQKGSKYVCLADKNCPVDKRRRNRCQFCRFQKCLVVGMVKEVVRTDSLKGRRGRLPSKPKSPQE-SPPSPPISLITALVRSHVDTTPDPSCLDYSHYEE-----QSMSEADKVQQFYQLLTSSVDVIKQFAEKIPGYFDLLPEDQELLFQSASLELFVLRLAYRARIDDTKLIFCNGTVLHRTQCLRSFGEWLNDIMEFSRSLHNLEIDISAFACLCALTLITERHGLREPKKVEQLQMKIIGSLRDHVTYNAEAQKKQHYFSRLLGKLPELRSLSVQGLQRIFYLKLEDLVPAPALIENMFVTTLPF", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :.* .:. ..* .:.. * * * :.:.*: .. *** . : *** * * ***:: :**:.* :: : *:* . :*.. : :: * : :*:.** * :: : . *..: . . *. . ::.* . .* . :* : ::* ..:. :*.*:*::.* * *:*. . *: . : : .. .: : ...: *.*.. ::. * :... .*. ** .: .:..* .*.. :. *******.************************.:******:**************:*******.***********.****************: ******:***:****:***:.* ..***:::: * .:::::****:***.*:::*: :******: ** **:***:** ***********:. : *******.**** **:*.****::.*:*** .*:*:::*****:*:.**:::******:***:**:** **:..*:*:**:* . :: :*:*:*********:*..****************.**:*:::*: ****", "identical_positions": 279, "similar_positions": 190, "identity": "25.86%" }, { "cls_id": "homologset.agr.MGI:1352457", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P51179-1", "uniprot_id": "NR4A3_RAT", "id": "P51179-1", "name": "Nuclear receptor subfamily 4 group A member 3", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MPCVQAQYSPSPPG--------------------STYATQTYG--SEYTTEIMNP-DYAKLTMDLGSTGIMATATTSLPS---------------FSTFMEGYPSSCELKPSCLYQMPPSGPRPLIKMEEGREHGYHHHHHHHHHHHHHHQQQQ--PSIPPPSGPEDE--VLP-----------STSMYFKQSPPSTPTTPGFP--PQAGALWDD-ELPSAPG-CIAPGPLLDPQMKAVPPMAAAARFPIF-FKPSPPHPPAPSP-------------AGGHHLGYDPTAAAALSLPLGAAAAAG--------SQAAALEGHPYG-----------------LPLAK-RTATLTFPPLG------------------------------LTASPTASSLLGESPSLPSPPNRSSSS--------------GEGTCAVCGDNAACQHYGVRTCEGCKGFFKRTVQKNAKYVCLANKNCPVDKRRRNRCQYCRFQKCLSVGMVKEVVRTDSLKGRRGRLPSKPKSPLQQEPSQPSPPSPPICMMNALVRALTDATPRDLDYSRYCPTDQATAGTDAEHVQQFYNLLTASIDVSRSWAEKIPGFTDLPKEDQTLLIESAFLELFVLRLSIRSNTAEDKFVFCNGLVLHRLQCLRGFGEWLDSIKDFSLNLQSLNLDIQALACLSALSMITERH-GLKEPKRVEELCNKITSSLKDHQ---------RKGQALEPSEPKVLRALVELRKICTQGLQRIFYLKLEDLVSPPSVIDKLFLDTLPF", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9QZB6-1", "uniprot_id": "NR4A3_MOUSE", "id": "Q9QZB6-1", "name": "Nuclear receptor subfamily 4 group A member 3", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MPCVQAQYSPSPPG--------------------STYATQTYG--SEYTTEIMNP-DYTKLTMDLGSTGIMATATTSLPS---------------FSTFMEGYPSSCELKPSCLYQMPPSGPRPLIKMEEGREHGYHHHHHHHHHHHHHQQQQ---PSIPPPSGPEDE--VLP-----------STSMYFKQSPPSTPTTPGFP--PQAGALWDD-ELPSAPG-CIAPGPLLDPQMKAVPPMAAAARFPIF-FKPSPPHPPAPSP-------------AGGHHLGYDPTAAAALSLPLGAAAAAG--------SQAAALEGHPYG-----------------LPLAK-RTATLTFPPLG------------------------------LTASPTASSLLGESPSLPSPPNRSSSS--------------GEGTCAVCGDNAACQHYGVRTCEGCKGFFKRTVQKNAKYVCLANKNCPVDKRRRNRCQYCRFQKCLSVGMVKEVVRTDSLKGRRGRLPSKPKSPLQQEPSQPSPPSPPICMMNALVRALTDATPRDLDYSRYCPTDQATAGTDAEHVQQFYNLLTASIDVSRSWAEKIPGFTDLPKEDQTLLIESAFLELFVLRLSIRSNTAEDKFVFCNGLVLHRLQCLRGFGEWLDSIKDFSLNLQSLNLDIQALACLSALSMITERH-GLKEPKRVEELCTKITSSLKDHQ---------RKGQALEPSEPKVLRALVELRKICTQGLQRIFYLKLEDLVPPPSVIDKLFLDTLPF", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q92570-1", "uniprot_id": "NR4A3_HUMAN", "id": "Q92570-1", "name": "Nuclear receptor subfamily 4 group A member 3", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MPCVQAQYSPSPPG--------------------SSYAAQTYS--SEYTTEIMNP-DYTKLTMDLGSTEITATATTSLPS---------------ISTFVEGYSSNYELKPSCVYQMQ----RPLIKVEEGRAPSYHHHHHHHHHHHHHHQQQHQQPSIPPASSPEDE--VLP-----------STSMYFKQSPPSTPTTPAFP--PQAGALWDE-ALPSAPG-CIAPGPLLDPPMKAVP-TVAGARFPLFHFKPSPPHPPAPSP-------------AGGHHLGYDPTAAAALSLPLGAAAAAG--------SQAAALESHPYG-----------------LPLAK-RAAPLAFPPLG------------------------------LTPSPTASSLLGESPSLPSPPSRSSSS--------------GEGTCAVCGDNAACQHYGVRTCEGCKGFFKRTVQKNAKYVCLANKNCPVDKRRRNRCQYCRFQKCLSVGMVKEVVRTDSLKGRRGRLPSKPKSPLQQEPSQPSPPSPPICMMNALVRALTDSTPRDLDYSRYCPTDQAAAGTDAEHVQQFYNLLTASIDVSRSWAEKIPGFTDLPKEDQTLLIESAFLELFVLRLSIRSNTAEDKFVFCNGLVLHRLQCLRGFGEWLDSIKDFSLNLQSLNLDIQALACLSALSMITERH-GLKEPKRVEELCNKITSSLKDHQ---------SKGQALEPTESKVLGALVELRKICTLGLQRIFYLKLEDLVSPPSIIDKLFLDTLPF", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M3AQK6-1", "uniprot_id": "A0A8M3AQK6_DANRE", "id": "A0A8M3AQK6-1", "name": "Nuclear receptor subfamily 4 group A member 2", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MLSSRHCDCRYSETPVRKSACSPGLGPGYRIPHPPRVLKQPRTPDACSLHSKNRPRFSEQKANQIYGT--------------LTMNKRSQLLEQLHFVHLKCTPRVDMPCVQAQYGPPPHG--------------------SSYSAQSFGYHGDYSADLMAT-DYTKCELSGGEIS-AAAATTSLPS---------------FNVFVEG---GFEPKPSCLYQLPPQ--RPIIKKEE--------------------------ESFPP-MAPSDE--AIP-----------GSSMYFKQSPPSTPPTPLHPGPPSSSFLWDEHSLPPVPQPCLIEGPLKSP------------RFPHFYEQTVPPSTSGYDT-------------AIGLPLRPERSPSSSSSSSHVPPNMDT--------HAHSHVHSHTHSNM---------------YPINMGKPGGLAFRSLG------------------------------MGHCP---PLLGES--LPSPPNRTSS---------------GEGTCAVCGDNAACQHYGVRTCEGCKGFFKRTVQKNAKYVCLASKNCPVDKRRRNRCQYCRFQKCLSVGMVKEVVRTDNLKGRRGRLPSKPKSPLQPEP---SPPSPPLSLLNALVRAYSQSTPRELDYSQFSAVEPVGLS-ESQQIQMFYRVLTGSMEVTRCWAERLPGFSELHHDDQNMLIDSAFLELFVLRLANRSLLVDEKFVFCTGLVLHRLQCLRGFGEWLDSIRDFSAHLQELNLDMPAFSCLCALVLLTEQCPGLKEPKKVEELQSKLICCLRDHLNSINAGGVASTGKAPPPVG-AVLGLRAELRSQRTQGLQRIFYLKLEDLVPPPPLIDR-FLDTLPY", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P49869-1", "uniprot_id": "HR38_DROME", "id": "P49869-1", "name": "Probable nuclear hormone receptor HR38", "aln": "MMRDRLASLIVVKQEGGSNTSISHHQATAIKCEASLYTESSLFQEINNNSCYRQNLNAPTHQQSHTSHLQHAQQHQTHQQHPLLPPPLPTLPLIYPCRNLFPDGCDINHLACCSSSNSNSNCNSDSNSTSSSPGNSHFFANGNTCAAALTPAPPATEPRKIKPLGAGKLKVGKTDSNSDSNSNCDSRAAAAASTSATSATSATTLAATAAATAAAAEAGGAASAAAAAKISQVRLTNQATTSMLLLQPNSSFSSLSPFDNFSTQTASTTTTTSASAAGHHQHHNHLLHQQHHNQQQQQQQQQQQQQQQQQQQEHLQQQHQQQLVSPQQHLLKSETLLSHEEDQLISNLTDSSVVSHSELFSDLFFPSDSNNSLLSPTTSGYPDNPAEDLTSSIENLTKLTCLRDKRLSSIPEQQLSSEQEQQLCLLSLRSS-SDPAIALHAQQQQQQQQQQQQQQQQHQQQQQHLQLQLISPIGGPLSCGSSLPSFQETYSLKYNSSSGSSPQQASSSSTAAPTPTDQVLTLKMDEDCFPPLSG-GWSASPPAPSQLQQLHTLQSQAQMSHPNSSNNSSNNAGNSHNNSGGYNYHGHFNAINASANLSPSSSASSLYEYNGVSAADNFYGQQQQQQQQSYQQHNYNSHNGERYSLPTFPTISELAAATAAVEAAAAATVGGPPPVRRASLPVQRTVSPAGSTAQSPKLAKITLNQRHSHAHAHALQLNSAPNSAASSPASADLQAGRLLQAPSQLCAVCGDTAACQHYGVRTCEGCKGFFKRTVQKGSKYVCLADKNCPVDKRRRNRCQFCRFQKCLVVGMVKEVVRTDSLKGRRGRLPSKPKSPQ------ESPPSPPISLITALVRSHVDTTP-DPSCLDYSHYEEQSMS-EADKVQQFYQLLTSSVDVIKQFAEKIPGYFDLLPEDQELLFQSASLELFVLRLAYRARIDDTKLIFCNGTVLHRTQCLRSFGEWLNDIMEFSRSLHNLEIDISAFACLCALTLITERH-GLREPKKVEQLQMKIIGSLRDHVTYN------AEAQKKQHYFSRLLGKLPELRSLSVQGLQRIFYLKLEDLVPAPALIENMFVTTLPF", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :* *: . *. : .: .: :::: . * : :. .: .*.* :. : * . : : *: .: * * . :.* .* . :* .:* *...*:..:. * *: :*. . .* . ::. . .. .. . * . . :.::: . * :. . : .:* : ..: * *.*. ::* . ******.************************.:******.**************:******* ***********.*************** ******:.::.****: ::** : . :. : . :::::* **.:**.*::* : :**::**: :* :** :*::** ********: *: : *::**.* **** ****.*****:.* :** *:.*::*: *::**.** ::**: **:***:**:* *: .*:** .: :* ***. . **************..*.:*:. *: ***:", "identical_positions": 214, "similar_positions": 164, "identity": "19.63%" }, { "cls_id": "homologset.agr.MGI:1352459", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I5Y5U9-1", "uniprot_id": "A0A8I5Y5U9_RAT", "id": "A0A8I5Y5U9-1", "name": "Nuclear receptor subfamily 6 group A member 1", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MCVAAARDVRGGSWPVLRGRGAEGRGAGWLRGPECSAAESLPAPDSPLPPGGRPGRRLRGRRSWRNIEASEGPEHRRMERDERPPS-GGGGGG-GSAGFLE-----------------------------------------------------------------------------PPAALPPPPRNGFCQDELAELDPGTNGETDGLTLGQGHIPVSVPDDRAEQRTCLICGDRATGLHYGIISCEGCKGFFKRSICNKRVYRCSRDKNCVMSRKQRNRCQYCRLLKCLQMGMNRKAIREDGMPGGRN----------------------------KSIGPVQISEEEIERIMSGQEFEEEANH----WSNHGDSDHSSPGNRVSESNQPSPGSTLSSSR-------------------------SVELNGF-MTFRDQYMGMSVPPHYQYIPHLFSYSGHSPLLPPQARSLDPQSYS----------------------------------------------------------------------------------LIHQLMSAEDLEPLGTPMLIEDGYAVTQAELFALLCRLADELLFRQIAWIKKLPFFCELSIKDYTCLLSSTWQELILLSSLTVYSKQ----------------------------------------------------IFGELADVTAKYSPSDEELHRFSDEGMEVIERLIYLYHKFHQLKVSNEEYACMKAINFLNQDIRGLSSASQLEQLNKRYWYICQDFTEYKYTHQP-NRFPDLMMCLPEIRYIAGKMVNVPLEQLPLLFKVVLHSCKTSTVKE----------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q64249-1", "uniprot_id": "NR6A1_MOUSE", "id": "Q64249-1", "name": "Nuclear receptor subfamily 6 group A member 1", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MERDERPPS-GGGGGG-GSAGFLE-----------------------------------------------------------------------------PPAALPPPPRNGFCQDELAELDPGTNGETDSLTLGQGHIPVSVPDDRAEQRTCLICGDRATGLHYGIISCEGCKGFFKRSICNKRVYRCSRDKNCVMSRKQRNRCQYCRLLKCLQMGMNRKAIREDGMPGGRN----------------------------KSIGPVQISEEEIERIMSGQEFEEEANH----WSNHGDSDHSSPGNRASESNQPSPGSTLSSSR-------------------------SVELNGF-MAFRDQYMGMSVPPHYQYIPHLFSYSGHSPLLPPQARSLDPQSYS----------------------------------------------------------------------------------LIHQLMSAEDLEPLGTPMLIEDGYAVTQAELFALLCRLADELLFRQIAWIKKLPFFCELSIKDYTCLLSSTWQELILLSSLTVYSKQ----------------------------------------------------IFGELADVTAKYSPSDEELHRFSDEGMEVIERLIYLYHKFHQLKVSNEEYACMKAINFLNQDIRGLTSASQLEQLNKRYWYICQDFTEYKYTHQP-NRFPDLMMCLPEIRYIAGKMVNVPLEQLPLLFKVVLHSCKTSTVKE----------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q15406-1", "uniprot_id": "NR6A1_HUMAN", "id": "Q15406-1", "name": "Nuclear receptor subfamily 6 group A member 1", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MERDEPPPS-GGGGGG-GSAGFLE-----------------------------------------------------------------------------PPAALPPPPRNGFCQDELAELDPGT---------------ISVSDDRAEQRTCLICGDRATGLHYGIISCEGCKGFFKRSICNKRVYRCSRDKNCVMSRKQRNRCQYCRLLKCLQMGMNRKAIREDGMPGGRN----------------------------KSIGPVQISEEEIERIMSGQEFEEEANH----WSNHGDSDHSSPGNRASESNQPSPGSTLSSSR-------------------------SVELNGF-MAFREQYMGMSVPPHYQYIPHLFSYSGHSPLLPQQARSLDPQSYS----------------------------------------------------------------------------------LIHQLLSAEDLEPLGTPMLIEDGYAVTQAELFALLCRLADELLFRQIAWIKKLPFFCELSIKDYTCLLSSTWQELILLSSLTVYSKQ----------------------------------------------------IFGELADVTAKYSPSDEELHRFSDEGMEVIERLIYLYHKFHQLKVSNEEYACMKAINFLNQDIRGLTSASQLEQLNKRYWYICQDFTEYKYTHQP-NRFPDLMMCLPEIRYIAGKMVNVPLEQLPLLFKVVLHSCKTSVGKE----------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9PU65-1", "uniprot_id": "GCNFA_DANRE", "id": "Q9PU65-1", "name": "Nuclear receptor subfamily 6 group A member 1-A", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MVDKTHET-EFSKKQ-LEASSSG-----------------------------------------------------------------------------HGGVLIDAEENG-------------------------------IHDQAEQRSCLICGDRATGLHYGIISCEGCKGFFKRSICNKRVYRCSRDKNCEMSRKQRNRCQYCRLLKCLQMGMNRKAIREDGMPGGRN----------------------------KSIGPVQISDEEIERIMSGQEFKDEANMPEHTWGNNGDSDHSSPGNGVSDGNQPSPVSTLSSNR-------------------------SVELNGYTTALREQYIGNAMAQHYQFLPHLFGYA-------AQPRSLYPQSHT----------------------------------------------------------------------------------LIGQLVAAEDLAPLGTPMLIEDGYRVTQVELFALLCRLADELLFRQISWIKKLPFFCDLSIEDYTRLLSATWQELILLACLTVYSAQ----------------------------------------------------VLGDLANVTHKYTPSDDELHSFSEDGMEVMEKLIYLFRKFHQLKVSNEEYACMKAINFLNQDIRGLTNVTQLEQLNKRYWYVCQDYTEYKYPHQP-KRFPEIMMCLPEIRCIAGKLVNIPLEQLPLLFKAVLHSCKSSLSSYRTSSSPCVTKGTAPAN", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q4V8R7-1", "uniprot_id": "GCNFB_DANRE", "id": "Q4V8R7-1", "name": "Nuclear receptor subfamily 6 group A member 1-B", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MEVENRPNTYDFSKRDKLLSNRFY-----------------------------------------------------------------------------EENSLQDETDDG------------------------------------GERWCLICGDRASGLHYGIISCEGCKGFFKRSICNKRIYRCNRDKNCQMSRKQRNRCQYCRLQKCLQMGMNRKAIREDGMPGGRN----------------------------KMIGPVHISLEEIERLMSGQEFKEGSDLS--DSWSHGYSNHSSPGNSLSEGGQS---LSFSSSR-------------------------SVS-------CRDECISPQLTHTFLMCKYPLP--------PPTGSILKTQTHT----------------------------------------------------------------------------------LTGQILADEDLTPLTTPMLIEDGYSVTQSELLALLCGIADELLFRQIVWLKRLPFFTDLSIKDCTRLLGSSWHQLILLSSITVHSAQ----------------------------------------------------ILGELANVTHHYTPSSHTLQRFGEDAMEVMESLNFLFRKFHQLNISNEEYSCLKTITLLNQETTGLCNTSMLKQLSERYWTLCRELTERLHPQRP-KRFSDIITCLTEIRHTSGKMMSIPLEQLPLLFKAVLYSCTTNQNPWLPKSSTSRT-------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9W539-1", "uniprot_id": "HR4_DROME", "id": "Q9W539-1", "name": "Hormone receptor 4", "aln": "MTLSRGPYSELDKMSLFQDLKLKRRKIDSRCSSDGESIADTSTSSPDLLAPMSPKLCDSGSAGASLGASLPLPLALPLPMALPLPMSLPLPLTAASSAVTVSLAAVVAAVAETGGAGAGGAGTAVTASGAGPCVSTSSTTAAAATSSTSSLSSSSSSSSSTSSSTSSASPTAGASSTATCPASSSSSSGNGSGGKSGSIKQEHTEIHSSSSAISAAAASTVMSPPPAEATRSSPATPEGGGPAGDGSGATGGGNTSGGSTAGVAINEHQNNGNGSGGSSRASPDSLEEKPSTTTTTGRPTLTPTNGVLSSASAGTGISTGSSAKLSEAGMSVIRSVKEERLLNVSSKMLVFHQQREQETKAVAAAAAAAAAGHVTVLVTPSRIKSEPPPPASPSSTSSTQRERERERDRERDRERERERDRDREREREQSISSSQQHLSRVSASPPTQLSHGSLGPNIVQTHHLHQQLTQPLTLRKSSPPTEHLLSQSMQHLTQQQAIHLHHLLGQQQQQQQASHPQQQQQQQHSPHSLVRVKKEPNVGQRHLSPHHQQQSPLLQHHQQQQQQQQQQQQHLHQQQQQQQHHQQQPQALALMHPASLALRNSNRDAAILFRVKSEVHQQVAAGLPHLMQSAGGAAAAAAAAVAAQRMVCFSNARINGVKPEVIGGPLGNLRPVGVGGGNGSGSVQCPSPHPSSSSSSSQLSPQTPSQTPPRGTPTVIMGESCGVRTMVWGYEPPPPSAGQSHGQHPQQQQQSPHHQPQQQQQQQQQQSQQQQQQQQQQSLGQQQHCLSSPSAGSLTPSSSSGGGSVSGGGVGGPLTPSSVAPQNNEEAAQLLLSLGQTRIQDMRSRPHPFRTPHALNMERLWAGDYSQLPPGQLQALNLSAQQQQWGSSNSTGLGGVGGGMGGRNLEAPHEPTDEDEQPLVCMICEDKATGLHYGIITCEGCKGFFKRTVQNRRVYTCVADGTCEITKAQRNRCQYCRFKKCIEQGMVLQAVREDRMPGGRNSGAVYNLYKVKYKKHKKTNQKQQQQAAQQQQQQAAAQQQHQQQQQHQQHQQHQQQQLHSPLHHHHHQGHQSHHAQQQHHPQLSPHHLLSPQQQQLAAAVAAAAQHQQQQQQQQQQQQQAKLMGGVVDMKPMFLGPALKPELLQAPPMHSPAQQQQQQQQQQQQQQASPHLSLSSPHQQQQQQQGQHQNHHQQQGGGGGGAGGGAQLPPHLVNGTILKTALTNPSEIVHLRHRLDSAVSSSKDRQISYEHALGMIQTLIDCDAMEDIAT-LPHFSEFLEDKSEISEKLCNIGDSIVHKLVSWTKKLPFYLEIPVEIHTKLLTDKWHEILILTTAAYQALHGKRRGEGGGSRHGSPASTPLSTPTGTPLSTPIPSPAQPLHKDDPEFVSEVNSHLSTLQTCLTTLMGQPIAMEQLKLDVGHMVDKMTQITIMFRRIKLKMEEYVCLKVYILLNKEVE-------LESIQERYVQVLRSYLQNSSPQNPQARLSELLSHIPEIQAAASLLLESKMFYVPFVLNSASIR------------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :: . :. * .. *:** *:*:*******:**********:: *:*:* * * .* ::: *********: **:: ** :*:*** ****** : . . :. :: *. :. : : ..*.* .. * :*..: ... : :. : ...: : :: : : : * : . : : *: ** :.*.::.: : * *:***: ::.:: * ** .*:::::*: : : : :. * . :. : : .::: : : *:::::. *** *:*. :**:: *:.:.:** : :. : .:.* *:.::: :.**: :. ::. : :*:::: . ", "identical_positions": 89, "similar_positions": 148, "identity": "5.74%" }, { "cls_id": "homologset.agr.MGI:1352460", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q61066-1", "uniprot_id": "NR0B1_MOUSE", "id": "Q61066-1", "name": "Nuclear receptor subfamily 0 group B member 1", "aln": "MAGEDHPWQGSILYNLLMSAKQKHASQEEREVRLGAQCWGCACGAQPVLGGERLSGGQARSLLYRCCFCGENHPRQGGILYSMLTNARQPSVATQAPRARFGAPCWGCACGSAEPLVGREGLPAGQAPSLLYRCCFCGEEHPRQGSILYSLLTSAQQTHVSREAPEAHRRGEWWQLSYCTQSVGGPEGLQSTQAMAFLYRSYVCGEEQPQQISVASGTPVSADQTPATPQEQPRAPWWDASPGVQRLITLKDPQVVCEAASAGLLKTLRFVKYLPCFQILPLDQQLVLVRSCWAPLLMLELAQDHLHFEMMEIPETNTTQEMLTTRRQETEGPEPAEPQATEQPQMVSAEAGHLLPAAAVQAIKSFFFKCWSLNIDTKEYAYLKGTVLFNPDLPGLQCVKYIEGLQWRTQQILTEHIRMMQREYQIRSAELNSALFLLRFINSDVVTELFFRPIIGAVSMDDMMLEMLCAKL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P70503-1", "uniprot_id": "NR0B1_RAT", "id": "P70503-1", "name": "Nuclear receptor subfamily 0 group B member 1", "aln": "MAGEDHPWHGSILYNLLMSAKQKHGSREEREVRLGAQCWGCACGTQPVLGGEGLPGGQALSLLYRCCFCGENHPRQGGILYSMLTNARQPSGATEAPRARFRTPCWGCACSNAKPLVGRXGLPAGQVPSLLYRCCFCGKKHPRQGSILYSLLTNAQQTHVSREVPEAHRGGEWWQLSYCTHNVGGPEGLQSTQAMAFLYRSYVCCEEQPQQSSVASDTPVRADQTPAAPQEQPRAPWWDTSSGVQRPIALKDPQVVCEAASAGLLKTLRFVKYLPCFQILPLDQQLVLVRSCWAPLLMLELAQDHLHFEMMEISEPNLMHEMLTTRRQETEGPEPADPQATEQPQTVSAEAGHVLSVAAVQAIKSFFFKCWSLNIDTKEYAYLKGTVLFNPDLPGLQCVKYIESLQWRTQQILTEHIRLMQREYQIRSAELNSALFLLRFINTDVVTELFFRPIIGAVSMDDMMLEMLCAKL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P51843-1", "uniprot_id": "NR0B1_HUMAN", "id": "P51843-1", "name": "Nuclear receptor subfamily 0 group B member 1", "aln": "MAGENHQWQGSILYNMLMSAKQTRAAPEAPETRLVDQCWGCSCGDEPGVGREGLLGGRNVALLYRCCFCGKDHPRQGSILYSMLTSAKQTYAAPKAPEATLG-PCWGCSCG-SDPGVGRAGLPGGRPVALLYRCCFCGEDHPRQGSILYSLLTSSKQTHVAPAAPEARPGGAWWDRSYFAQRPGGKEALPGGRATALLYRCCFCGEDHPQQGSTLYCVPTSTNQAQAAPEERPRAPWWDTSSGALRPVALKSPQVVCEAASAGLLKTLRFVKYLPCFQVLPLDQQLVLVRNCWASLLMLELAQDRLQFETVEVSEPSMLQKILTTRRRETGGNEPLPVPTLQHHLAPPAEARKVPSASQVQAIKCFLSKCWSLNISTKEYAYLKGTVLFNPDVPGLQCVKYIQGLQWGTQQILSEHTRMTHQGPHDRFIELNSTLFLLRFINANVIAELFFRPIIGTVSMDDMMLEMLCTKI", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "****:* *:******:******.:.: * *.** *****:** :* :* * * **: :*********::*****.*******.*:*. *.:**.* : *****:*. :.* *** ***.*: :*********:.*************.::****: .***: * **: ** :: ** *.* . :* *:***. .* *::*** *. .*. ::*: *:*:*:*******:*.*. * ::**.**************************:***********.***.*********:*:** :*:.*.. :::*****:** * ** : :: .*** :: ..: *****.*: *******.****************:*********:.*** *****:** *: :: : * ****:********::*::*********:************:*:", "identical_positions": 294, "similar_positions": 106, "identity": "62.29%" }, { "cls_id": "homologset.agr.MGI:1352462", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q62685-1", "uniprot_id": "NR1H3_RAT", "id": "Q62685-1", "name": "Oxysterols receptor LXR-alpha", "aln": "------------------------------------MS-------------LWLEAAVP-DVSPDSATELWKTEPQDAG--DQGGNTCILREEARMPQS-----------------------------TGGALRIGLESSEPTALL---------------------------------------------------------------------PRAETLPEPTELR-------------------PQKRKKGPAPKMLGNELCSVCGDKASAFHYNVLSCEGCKGFFRRSVIKGARYICHSGGHCPMDTYMRRKCQECRLRKCRHAGMREECVLSEEQIRLKKLKRQEEEQAQATSVSPR--------------------------------------------VSSPPQVLPQLSPEQLGMIEKLVAAQQQCNRRSFSDRLRVTPWPIAPDPQSREARQQRFAHFTELAIVSVQEIVDFAKQLPGFLQLSREDQIALLKTSAIEVMLLETSRRYNPGSESITFLKDFSYNREDFAKAGLQVEFINPIFEFSRSMNELQLNDAEFALLIAISIFSADRPNVQDQLQVERLQHTYVEALHAYVSINHPHD---RLMFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9Z0Y9-1", "uniprot_id": "NR1H3_MOUSE", "id": "Q9Z0Y9-1", "name": "Oxysterols receptor LXR-alpha", "aln": "------------------------------------MS-------------LWLEASMP-DVSPDSATELWKTEPQDAG--DQGGNTCILREEARMPQS-----------------------------TGVALGIGLESAEPTALL---------------------------------------------------------------------PRAETLPEPTELR-------------------PQKRKKGPAPKMLGNELCSVCGDKASGFHYNVLSCEGCKGFFRRSVIKGARYVCHSGGHCPMDTYMRRKCQECRLRKCRQAGMREECVLSEEQIRLKKLKRQEEEQAQATSVSPR--------------------------------------------VSSPPQVLPQLSPEQLGMIEKLVAAQQQCNRRSFSDRLRVTPWPIAPDPQSREARQQRFAHFTELAIVSVQEIVDFAKQLPGFLQLSREDQIALLKTSAIEVMLLETSRRYNPGSESITFLKDFSYNREDFAKAGLQVEFINPIFEFSRAMNELQLNDAEFALLIAISIFSADRPNVQDQLQVERLQHTYVEALHAYVSINHPHD---PLMFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q13133-1", "uniprot_id": "NR1H3_HUMAN", "id": "Q13133-1", "name": "Oxysterols receptor LXR-alpha", "aln": "------------------------------------MS-------------LWLGAPVP-DIPPDSAVELWKPGAQDASSQAQGGSSCILREEARMPHS-----------------------------AGGTAGVGLEAAEPTALL---------------------------------------------------------------------TRAEPPSEPTEIR-------------------PQKRKKGPAPKMLGNELCSVCGDKASGFHYNVLSCEGCKGFFRRSVIKGAHYICHSGGHCPMDTYMRRKCQECRLRKCRQAGMREECVLSEEQIRLKKLKRQEEEQAHATSLPPR--------------------------------------------ASSPPQILPQLSPEQLGMIEKLVAAQQQCNRRSFSDRLRVTPWPMAPDPHSREARQQRFAHFTELAIVSVQEIVDFAKQLPGFLQLSREDQIALLKTSAIEVMLLETSRRYNPGSESITFLKDFSYNREDFAKAGLQVEFINPIFEFSRAMNELQLNDAEFALLIAISIFSADRPNVQDQLQVERLQHTYVEALHAYVSIHHPHD---RLMFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A0R4IVP0-1", "uniprot_id": "A0A0R4IVP0_DANRE", "id": "A0A0R4IVP0-1", "name": "", "aln": "------------------------------------MS-------------TLSATDIT-DVGHGDSLGCDSEEGPSAA--MAEVKQEILSQTDLYNTS-----------------------------HDDLNDSMLMESNDIKMF---------------------------------------------------------------------FREDK--AAPEGQ-------------------PVKRKKGPAPKMLGNEVCSVCGDKASGFHYNVLSCEGCKGFFRRSVIKGAQYSCKNSGRCEMDMYMRRKCQQCRLRKCREAGMLEQCVLSEEQIRLKKMKKQEEETARTSTVAT----------------------------------------------PSPAPEMPPLAPEQQEMIEKLVAMQKQCNKRSFIDRPKVTPWPQSQDPQNREVRQQRFAHFTELAIMSVQEIVDFAKQLPGFLELTREDQIALLKTSTIEIMLLETSRRYNPAIDSITFLKDFTYNKEDFAKAGLQLEFINPIFEFSKGMNDLHLDEAEYALLIAINIFSADRPNVQDHELVERLQQPYVDALHSYIRIKRPND---HLMFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P34021-1", "uniprot_id": "ECR_DROME", "id": "P34021-1", "name": "Ecdysone receptor", "aln": "MKRRWSNNGGFMRLPEESSSEVTSSSNGLVLPSGVNMSPSSLDSHDYCDQDLWLCGNESGSFGGSNGHGLSQQQQSVITLAMHGCSSTLPAQTTIIPINGNANGNGGSTNGQYVPGATNLGALANGMLNGGFNGMQQQIQNGHGLINSTTPSTPTTPLHLQQNLGGAGGGGIGGMGILHHANGTPNGLIGVVGGGGGVGLGVGGGGVGGLGMQHTPRSDSVNSISSGRDDLSPSSSLNGYSANESCDAKKSKKGPAPRVQ-EELCLVCGDRASGYHYNALTCEGCKGFFRRSVTKSAVYCCKFGRACEMDMYMRRKCQECRLKKCLAVGMRPECVVPENQCAMKRREKKAQKEKDKMTTSPSSQHGGNGSLASGGGQDFVKKEILDLMTCEPPQHATIPLLPDEILAKCQARNIPSLTYNQLAVIYKLIWYQDGYEQPSEEDLRRIMSQPDENESQTDVS----FRHITEITILTVQLIVEFAKGLPAFTKIPQEDQITLLKACSSEVMMLRMARRYDHSSDSIFFANNRSYTRDSYKMAG-MADNIEDLLHFCRQMFSMKVDNVEYALLTAIVIFS-DRPGLEKAQLVEAIQSYYIDTLRIYILNRHCGDSMSLVFYAKLLSILTELRTLGNQNAEMCFSLKLKNRKLPKFLEEIWDVHAIPPSVQSHLQITQEENERLERAERMRASVGGAITAGIDCDSASTSAAAAAAQHQPQPQPQPQPSSLTQNDSQHQTQPQLQPQLPPQLQGQLQPQLQPQLQTQLQPQIQPQPQLLPVSAPVPASVTAPGSLSAVSTSSEYMGGSAAIGPITPATTSSITAAVTASSTTSAVPMGNGVGVGVGVGGNVSMYANAQTAMALMGVALHSHQEQLIGGVAVKSEHSTTA", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ** . .. ... . . : : . . : :: * : .. : . * ******:: :*:* ****:**.:***.*:************ *.* * *: . * ** *******:***:** .** :**:.*:* :*: ::: :: : .. . . :* *: :* :* **: *. :: * * :: . * :.:. * *:**::*::** **:*** **.* ::.:****:***:.: *:*:*. :***: . :** * :: :*.::.: ** : *: ::.*.: * .:::::.*:*** ** *** ***.::. ** :* *:::*: *: .: * :::.::* *..****.. ::* *:*:*:::*** :*.****** ", "identical_positions": 146, "similar_positions": 142, "identity": "16.5%" }, { "cls_id": "homologset.agr.MGI:1352463", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q62755-1", "uniprot_id": "NR1H2_RAT", "id": "Q62755-1", "name": "Oxysterols receptor LXR-beta", "aln": "-----------MSSP-TSSLDTPLPGNGSPQPSTSSTSPTIKE----------------------EGQE-----TDP-PPGSEGSSSAYIV--VILEP-------------------------------------------------------------------------------------------------------------------------------------------------EDEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVHGGAGRYACRGSGTCQMDAFMRRKCQLCRLRKCKEAGMREQCVLSEEQIRKKKIQKQQQQ-----QPPPPTEPASGSSARPAASPGTSEASSQGSGEGEGIQLTAAQELMIQQLVAAQLQCN-----------------KRSFSDQPKVTPWPLGADPQSRDARQQR-FAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPSRVEALQQPYVEALLSYTRIKRPQD---QLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q60644-1", "uniprot_id": "NR1H2_MOUSE", "id": "Q60644-1", "name": "Oxysterols receptor LXR-beta", "aln": "-----------MSSP-TSSLDTPVPGNGSPQPSTSATSPTIKE----------------------EGQE-----TDP-PPGSEGSSSAYIV--VILEP-------------------------------------------------------------------------------------------------------------------------------------------------EDEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVHGGAGRYACRGSGTCQMDAFMRRKCQLCRLRKCKEAGMREQCVLSEEQIRKKRIQKQQQQ-----QPPPPSEPAASSSGRPAASPGTSEASSQGSGEGEGIQLTAAQELMIQQLVAAQLQCN-----------------KRSFSDQPKVTPWPLGADPQSRDARQQR-FAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPSRVEALQQPYVEALLSYTRIKRPQD---QLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P55055-1", "uniprot_id": "NR1H2_HUMAN", "id": "P55055-1", "name": "Oxysterols receptor LXR-beta", "aln": "-----------MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKE----------------------EGPEPWPGGPDPDVPGTDEASSACSTDWVIPDP-------------------------------------------------------------------------------------------------------------------------------------------------EEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCN-----------------KRSFSDQPKVTPWPLGADPQSRDARQQR-FAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQD---QLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P34021-1", "uniprot_id": "ECR_DROME", "id": "P34021-1", "name": "Ecdysone receptor", "aln": "MKRRWSNNGGFMRLPEESSSEVTSSSNGLVLPSGVNMSPSSLDSHDYCDQDLWLCGNESGSFGGSNGHGLSQQQQSVITLAMHGCSSTLPAQTTIIPINGNANGNGGSTNGQYVPGATNLGALANGMLNGGFNGMQQQIQNGHGLINSTTPSTPTTPLHLQQNLGGAGGGGIGGMGILHHANGTPNGLIGVVGGGGGVGLGVGGGGVGGLGMQHTPRSDSVNSISSGRDDLSPSSSLNGYSANESCDAKKSKKGPAPRVQ-EELCLVCGDRASGYHYNALTCEGCKGFFRRSVTKS--AVYCCKFGRACEMDMYMRRKCQECRLKKCLAVGMRPECVVPENQCAMKRREKKAQKEKDKMTTSPSSQHGGNGSLASGGGQDFVKKEILDLMTCEPPQHATIPLLPDEILAKCQARNIPSLTYNQLAVIYKLIWYQDGYEQPSEEDLRRIMSQPDENESQTDVSFRHITEITILTVQLIVEFAKGLPAFTKIPQEDQITLLKACSSEVMMLRMARRYDHSSDSIFFANNRSYTRDSYKMAG-MADNIEDLLHFCRQMFSMKVDNVEYALLTAIVIFSD-RPGLEKAQLVEAIQSYYIDTLRIYILNRHCGDSMSLVFYAKLLSILTELRTLGNQNAEMCFSLKLKNRKLPKFLEEIWDVHAIPPSVQSHLQITQEENERLERAERMRASVGGAITAGIDCDSASTSAAAAAAQHQPQPQPQPQPSSLTQNDSQHQTQPQLQPQLPPQLQGQLQPQLQPQLQTQLQPQIQPQPQLLPVSAPVPASVTAPGSLSAVSTSSEYMGGSAAIGPITPATTSSITAAVTASSTTSAVPMGNGVGVGVGVGGNVSMYANAQTAMALMGVALHSHQEQLIGGVAVKSEHSTTA", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * * ** :.. ..** *. **: : :* . . . .**: . .* *. :* ******:: .*** ****:***:***.*:************.:. *.*: . :*:** :****** ***:** .*** :**:.*:* *: .*: *: .. .: ....: .... . : . * * :: * : *. .* : : .:.: .: : ::*:..::: : * *:**::*::** **:*** :*.* :: :****:****.: *:*:*. ****:*.::.* * :: :*::*.:: ** .: *: ::.*.* * : :*:.***** ** *** **.:::. ***:*. *:::* * :: * : :.::* *..****.. ::* *:*:*:::*** :*.****** ", "identical_positions": 160, "similar_positions": 154, "identity": "18.12%" }, { "cls_id": "homologset.agr.MGI:1352464", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q96RI1-3", "uniprot_id": "NR1H4_HUMAN", "id": "Q96RI1-3", "name": "Bile acid receptor", "aln": "MVMQFQGLENPIQISPHCSCTPSGFFMEMMSMKPAKGVLTEQVAGPLGQNLEVEPYSQYSNVQFPQVQPQISSSSYYSNLGFYPQQPEEWYSPGIYELRRMPAETLYQGETEVAEMPVTKKPRMG-ASAGRIKGDELCVVCGDRASGYHYNALTCEGCKGFFRRSITKNAVYKCKNGGNCVMDMYMRRKCQECRLRKCKEMGMLAECMYTGLLTEIQCKSKRLRKNVKQHADQTVNED-SEGRDLRQVTSTTKSCREKTELTPDQQTLLHFIMDSYNKQRMPQEITNKILKEEFSAEENFLILTEMATNHVQVLVEFTKKLPGFQTLDHEDQIALLKGSAVEAMFLRSAEIFNKKLPSGHSDLLEERIRNSGISDEYITPMFSFYKSIGELKMTQEEYALLTAIVILSPDRQYIKDREAVEKLQEPLLDVLQKLCKIHQPENPQHFACLLGRLTELRTFNHHHAEMLMSWRVNDHKFTPLLCEIWDVQ", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q60641-1", "uniprot_id": "NR1H4_MOUSE", "id": "Q60641-1", "name": "Bile acid receptor", "aln": "MVMQFQGLENPIQISLHHSHRLSGFVPEGMSVKPAKGMLTEHAAGPLGQNLDLESYSPYNNVPFPQVQPQISSSSYYSNLGFYPQQPEDWYSPGIYELRRMPAETGYQGETEVSEMPVTKKPRMAAASAGRIKGDELCVVCGDRASGYHYNALTCEGCKGFFRRSITKNAVYKCKNGGNCVMDMYMRRKCQECRLRKCKEMGMLAECMYTGLLTEIQCKSKRLRKNVKQHADQTANEDDSEGRDLRQVTSTTKFCREKTELTADQQTLLDYIMDSYNKQRMPQEITNKILKEEFSAEENFLILTEMATSHVQILVEFTKKLPGFQTLDHEDQIALLKGSAVEAMFLRSAEIFNKKLPAGHADLLEERIRKSGISDEYITPMFSFYKSVGELKMTQEEYALLTAIVILSPDRQYIKDREAVEKLQEPLLDVLQKLCKMYQPENPQHFACLLGRLTELRTFNHHHAEMLMSWRVNDHKFTPLLCEIWDVQ", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q62735-1", "uniprot_id": "NR1H4_RAT", "id": "Q62735-1", "name": "Bile acid receptor", "aln": "-----MNLIGPSHLQATDEFALS---------ENLFGVLTEHAAGPLGQNLDLESYSPYNNVQFPQVQPQISSSSYYSNLGFYPQQPEDWYSPGLYELRRMPTESVYQGETEVSEMPVTKKPRMAASSAGRIKGDELCVVCGDRASGYHYNALTCEGCKGFFRRSITKNAVYKCKNGGNCVMDMYMRRKCQDCRLRKCREMGMLAECLLT----EIQCKSKRLRKNVKQHADQTVNED-SEGRDLRQVTSTTKLCREKTELTVDQQTLLDYIMDSYSKQRMPQEITNKILKEEFSAEENFLILTEMATSHVQILVEFTKRLPGFQTLDHEDQIALLKGSAVEAMFLRSAEIFNKKLPAGHADLLEERIRKSGISDEYITPMFSFYKSVGELKMTQEEYALLTAIVILSPDRQYIKDREAVEKLQEPLLDVLQKLCKIYQPENPQHFACLLGRLTELRTFNHHHAEMLMSWRVNDHKFTPLLCEIWDVQ", "tax_id": 10116, "tax_name": "Rat" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .* .* ::. . * : *:***:.********::*.** *.** *************************:*****:*******:*: *******:**********. :****************************************************************:******:********: * ********************.*** ************** ******** ******.:*****.*******************************.***:******:*************************************:**:********:*****************:************************************************::**************************************************", "identical_positions": 413, "similar_positions": 37, "identity": "84.63%" }, { "cls_id": "homologset.agr.MGI:1352465", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8VIJ4-1", "uniprot_id": "NR2C1_RAT", "id": "Q8VIJ4-1", "name": "Nuclear receptor subfamily 2 group C member 1", "aln": "MATIEEIAHQIIDQQMGEIVTEQQTGQKIQIVTALDHSTQGKQFILANHEG------------STPGKVFLTTPDAAGVNQLFFASPDLSTPHLQLLTENSPDQGPNKVFDLCVVCGDKASGRHYGAITCEGCKGFFKRSIRKNLVYSCRGSKDCIINKHHRNRCQYCRLQRCIAFGMKQDSVQCERKPIEVSREKSSNCAAS--------------------------------------------------TEKIYIRKDLRSPLAATPTFVTDSETARSTGLLDSGMFVNIHPSGIKTEPALLMTPDKAESCQGDLGTLASVVTS---LANLGKAKDLSHCGGDLPVVQS------LRNGDTSFGAFHQDIQTNGDVSRAFDNLAKALTPGENPACQSPGESME-----GSTHLIAGEP--SCMEREGPLLSDSHVVFRLTMPSPMPEYLNVHYIGESASRLLFLSMHWALSIPSFQALGQENSISLVKAYWNELFTLGLAQCWQVMNVATILATFVNCLHNSLQQDKMSPERRKLLMEHIFKLQEFCNSMVKLCIDGHEYAYLKAIVLFSPDHPGLENMELIEKFQEKAYVEFQDYITRT--YPDDTYRLSRLLLRLPALRLMNATITEELFFKGLIGNVRIDSVIPHILKMEPADYNSQIIGHSL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q505F1-1", "uniprot_id": "NR2C1_MOUSE", "id": "Q505F1-1", "name": "Nuclear receptor subfamily 2 group C member 1", "aln": "MATIEEIAHQIIDQQMGEIVTEQQTGQKIQIVTALDHSTQGKQFILANHEG------------STPGKVFLTTPDAAGVNQLFFTSPDLSAPHLQLLTEKSPDQGPNKVFDLCVVCGDKASGRHYGAITCEGCKGFFKRSIRKNLVYSCRGSKDCVINKHHRNRCQYCRLQRCIAFGMKQDSVQCERKPIEVSREKSSNCAAS--------------------------------------------------TEKIYIRKDLRSPLAATPTFVTDSETARSAGLLDSGMFVNIHPSGIKTEPAMLMAPDKAESCQGDLSTLASVVTS---LANLGKAKDLSHCGGDMPVVQS------LRNGDTSFGAFHHDIQTNGDVSRAFDTLAKALTPGESSACQSPEEGME-----GSPHLIAGEP--SFVEKEGPLLSESHVAFRLTMPSPMPEYLNVHYIGESASRLLFLSMHWALSIPSFQALGQENSISLVKAYWNELFTLGLAQCWQVMNVATILATFVNCLHSSLQQDKMSPERRKSLMEHIFKLQEFCNSMVKLCIDGHEYAYLKAIVLFSPDHPGLENMELIERFQEKAYVEFQDYITRT--YPDDTYRLSRLLLRLPALRLMNATITEELFFKGLIGNVRIDSVIPHILKMEPADYNSQIIGHSL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P13056-1", "uniprot_id": "NR2C1_HUMAN", "id": "P13056-1", "name": "Nuclear receptor subfamily 2 group C member 1", "aln": "MATIEEIAHQIIEQQMGEIVTEQQTGQKIQIVTALDHNTQGKQFILTNHDGSTPSKVILARQDSTPGKVFLTTPDAAGVNQLFFTTPDLSAQHLQLLTDNSPDQGPNKVFDLCVVCGDKASGRHYGAVTCEGCKGFFKRSIRKNLVYSCRGSKDCIINKHHRNRCQYCRLQRCIAFGMKQDSVQCERKPIEVSREKSSNCAAS--------------------------------------------------TEKIYIRKDLRSPLTATPTFVTDSESTRSTGLLDSGMFMNIHPSGVKTESAVLMTSDKAESCQGDLSTLANVVTS---LANLGKTKDLSQNSNEMSMIES------LSNDDTSLCEF-QEMQTNGDVSRAFDTLAKALNPGESTACQSSVAGME-----GSVHLITGDSSINYTEKEGPLLSDSHVAFRLTMPSPMPEYLNVHYIGESASRLLFLSMHWALSIPSFQALGQENSISLVKAYWNELFTLGLAQCWQVMNVATILATFVNCLHNSLQQDKMSTERRKLLMEHIFKLQEFCNSMVKLCIDGYEYAYLKAIVLFSPDHPSLENMEQIEKFQEKAYVEFQDYITKT--YPDDTYRLSRLLLRLPALRLMNATITEELFFKGLIGNIRIDSVIPHILKMEPADYNSQIIGHSI", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q24142-1", "uniprot_id": "HR78_DROME", "id": "Q24142-1", "name": "Nuclear hormone receptor HR78", "aln": "-----------MDGVKVETFIKSEENRAMPLIGGGSASGG-------------------------------TPLPGGGVGMGAGASATLS-------------------VELCLVCGDRASGRHYGAISCEGCKGFFKRSIRKQLGYQCRGAMNCEVTKHHRNRCQFCRLQKCLASGMRSDSVQHERKPIVDRKEGIIAAAGSSSTSGGGNGSSTYLSGKSGYQQGRGKGHSVKAESAATPPVHSAPATAFNLNENIFPMGLNFAELTQTLMFATQQQQQQQQQHQQSGSYSPDIPKADPEDDEDDSMDNSSTLCLQLLANSASNNNSQHLNFNAGEVPTALPTTSTMGLIQSSLDMRVIHKGLQILQPIQNQLERNGNLSVKPECDSEAEDSGTEDAVDAELEHMELDFECGGNRSGGSDFAINEAVFEQDLLTDVQCAFHVQPPTLVHSYLNIHYVCETGSRIIFLTIHTLRKVPVFEQLEAHTQVKLLRGVWPALMAIALAQCQGQLSVPTIIGQFIQSTRQLADIDKIEPLKISKMANLTRTLHDFVQELQSLDVTDMEFGLLRLILLFNPTLLQQRKERSLRGYVRRVQLYALSSLRRQGGIGGGEERFNVLVARLLPLSSLDAEAMEELFFANLVGQMQMDALIPFILMTSNTSGL--------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :: * . :.: .: : :: . . . *. ..**. ::. ** .:**:****:********::**************:* *.***: :* :.********:****:*:* **:.**** ***** :* .*.* .*:*: : *: * *.*:.: :. :** : *.. : :.: * *.. *. .* * *:. . : :::* : :. : : :::: **::* : ::* .* . * :: ** *. : .: . * **:: : .*:: *: : .***:**: *:.**::**::* .:* *: * ...:.*::. * *:::.**** :.*.**:. *::. :. : **:.. : . : : .*::* :.: .* : . *:. *: *:**.* .: . :. : .:. : . : : .. *:. *: ** .* ::* ***** .*:*::::*::**.** . :. ", "identical_positions": 152, "similar_positions": 191, "identity": "22.69%" }, { "cls_id": "homologset.agr.MGI:1352466", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P55094-1", "uniprot_id": "NR2C2_RAT", "id": "P55094-1", "name": "Nuclear receptor subfamily 2 group C member 2", "aln": "MTSPSPRIQIISTDSAVRSPQRIQIVTDQQTGQKLQIVTAVDASGSSKQQFILTSPDGAGTGKVILASPETSSAKQLIFTTSDNLVPGRIQIVTDSASVERLLGK-ADVQRPQVVEYCVVCGDKASGRHYGAVSCEGCKGFFKRSVRKNLTYSCRSSQDCIINKHHRNRCQFCRLKKCLEMGMKMESVQSERKPFDVQREKPSNCAASTEKIYIRKDLRSPLIATPTFVADK---------DGSRQTGLLDPGMLVNIQQPLIRE-------DGTVLLATDSKAETSQGA------------------------------LGTLANVVTSLANLSESLNNGDASEMQPEDQSASEITRAFDT---------LAKALNTTDSASPPSLADGIDASG--GGSIHVISRDQSTPIIEVEG-------------------PLLSDTHVTFKLTMPSPMPEYLNVHYICESASRLLFLSMHWARSIPAFQALGQDCNTSLVRACWNELFTLGLAQCAQVMSLSTILAAIVNHLQNSIQE-DKLSGDRIKQVMEHIWKLQEFCNSMAKLDIDGHEYAYLKAIVLFSPDHPGLTGTSQIEKFQEKAQMELQDYVQKT--YSEDTYRLARILVRLPALRLMSSNITEELFFTGLIGNVSIDSIIPYILKMETAEYNGQITGASL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P49117-1", "uniprot_id": "NR2C2_MOUSE", "id": "P49117-1", "name": "Nuclear receptor subfamily 2 group C member 2", "aln": "MTSPSPRIQIISTDSAVASPQRIQIVTDQQTGQKIQIVTAVDASGSSKQQFILTSPDGAGTGKVILASPETSSAKQLIFTTSDNLVPGRIQIVTDSASVERLLGK-ADVQRPQVVEYCVVCGDKASGRHYGAVSCEGCKGFFKRSVRKNLTYSCRSSQDCIINKHHRNRCQFCRLKKCLEMGMKMESVQSERKPFDVQREKPSNCAASTEKIYIRKDLRSPLIATPTFVADK---------DGARQTGLLDPGMLVNIQQPLIRE-------DGTVLLAADSKAETSQGA------------------------------LGTLANVVTSLANLSESLNNGDASEMQPEDQSASEITRAFDT---------LAKALNTTDSASPPSLADGIDASG--GGSIHVISRDQSTPIIEVEG-------------------PLLSDTHVTFKLTMPSPMPEYLNVHYICESASRLLFLSMHWARSIPAFQALGQDCNTSLVRACWNELFTLGLAQCAQVMSLSTILAAIVNHLQNSIQE-DKLSGDRIKQVMEHIWKLQEFCNSMAKLDIDGYEYAYLKAIVLFSPDHPGLTGTSQIEKFQEKAQMELQDYVQKT--YSEDTYRLARILVRLPALRLMSSNITEELFFTGLIGNVSIDSIIPYILKMETAEYNGQITGASL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P49116-1", "uniprot_id": "NR2C2_HUMAN", "id": "P49116-1", "name": "Nuclear receptor subfamily 2 group C member 2", "aln": "MTSPSPRIQIISTDSAVASPQRIQIVTDQQTGQKIQIVTAVDASGSPKQQFILTSPDGAGTGKVILASPETSSAKQLIFTTSDNLVPGRIQIVTDSASVERLLGK-TDVQRPQVVEYCVVCGDKASGRHYGAVSCEGCKGFFKRSVRKNLTYSCRSNQDCIINKHHRNRCQFCRLKKCLEMGMKMESVQSERKPFDVQREKPSNCAASTEKIYIRKDLRSPLIATPTFVADK---------DGARQTGLLDPGMLVNIQQPLIRE-------DGTVLLATDSKAETSQGA------------------------------LGTLANVVTSLANLSESLNNGDTSEIQPEDQSASEITRAFDT---------LAKALNTTDSSSSPSLADGIDTSG--GGSIHVISRDQSTPIIEVEG-------------------PLLSDTHVTFKLTMPSPMPEYLNVHYICESASRLLFLSMHWARSIPAFQALGQDCNTSLVRACWNELFTLGLAQCAQVMSLSTILAAIVNHLQNSIQE-DKLSGDRIKQVMEHIWKLQEFCNSMAKLDIDGYEYAYLKAIVLFSPDHPGLTSTSQIEKFQEKAQMELQDYVQKT--YSEDTYRLARILVRLPALRLMSSNITEELFFTGLIGNVSIDSIIPYILKMETAEYNGQITGASL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AB32TYQ7-1", "uniprot_id": "A0AB32TYQ7_DANRE", "id": "A0AB32TYQ7-1", "name": "", "aln": "MSGSPQRIQIISTEPSVTSPQRIQIVTEQQTGQKIQIVTALDSS-VPKQQFLLASPDGSPAGKVLLASPESSSAKQLIFATADSLVPGRIQFVTDAVSVERLLGKGTDLSRVQPIEYCVVCGDKASGRHYGAVSCEGCKGFFKRSVRKSLTYSCRSNQDCVINKHHRNRCQFCRLRKCLEMGMKMESVQSERKPIDLPREKPANCAASTEKIYIRKDLRSPLIATPTFISEK---------DSSRSK-LLDSGMLVNIQQPLIQA-------DGTLLLATD-KTESGQGD------------------------------LGTLANVVTSLANLNDSLSNGEATDGQLEE-SPSEITRAFDT---------LAKALNPGELTESQSLSE-VDGVG--GATIQVISRDQISPLIEVEG-------------------PLLTDTHVSFKLTMPSPMPEYLNVHYICESASRLLFLSMHWARSIPAFLALGQECNTALVRACWNELFILGLAQCAQIMSLSTILTAIVNHLQSSIQDVDKLSSERIKLVMEHIWKLQEFCNSMAKLQTDAYEYAYLKAIVLFSPDHPGLSSCSQIEKFQEKAQMELQDYVQKT--YPDETYRLARILLRLPALRLMSSSITEELFFTGLIGNVPIDSIIPYILKMETADYNSQITAPSV", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q24142-1", "uniprot_id": "HR78_DROME", "id": "Q24142-1", "name": "Nuclear hormone receptor HR78", "aln": "-----------------MDGVKVETFIKSEENRAMPLIG-----------------GGSASGGTPLPGGG--------------------------------VGMGAGASATLSVELCLVCGDRASGRHYGAISCEGCKGFFKRSIRKQLGYQCRGAMNCEVTKHHRNRCQFCRLQKCLASGMRSDSVQHERKPIVDRKEGIIAAAGSSSTSGGGNGSSTYLSGKSGYQQGRGKGHSVKAESAATPPVHSAPATAFNLNENIFPMGLNFAELTQTLMFATQQQQQQQQQHQQSGSYSPDIPKADPEDDEDDSMDNSSTLCLQLLANSASNNNSQHLNFNAGEVPTALPTTSTMGLIQSSLDMRVIHKGLQILQPIQNQLERNGNLSVKPECDSEAEDSGTEDAVDAELEHMELDFECGGNRSGGSDFAINEAVFEQDLLTDVQCAFHVQPPTLVHSYLNIHYVCETGSRIIFLTIHTLRKVPVFEQLEAHTQVKLLRGVWPALMAIALAQCQGQLSVPTIIGQFIQSTR-QLADIDKIEPLKISKMANLTRTLHDFVQELQSLDVTDMEFGLLRLILLFNPTLLQQRKERSLRGYVRRVQLYALSSLRRQGGIGGGEERFNVLVARLLPLSSLDAEAMEELFFANLVGQMQMDALIPFILMTSNTSGL--------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . ::: . ..: .: : :: .*: :* . *.. :* :. . :* *:****:********:************:**.* *.**. :* :.************:*** **: :*** ****: :* .*.*:.. :. : * ... : : ..: .. .*::: :: *:::*:: : : * * *** .:. . .:. *:.. : . * ::* * * : *: * . ..: ..:. : ::.* **:*.: :*:: *: : .***:**:**:.**::**::* *.:*.* * . :. *:*. * *: :.**** :*:.**: ::: : .: : **:. :*. : : .*::* :.: .*: *:. *: *:**.* .:. : .:.*: . ::: *: :: ** .* :.:. *****:.*:*:: :*::**:** ..:. ", "identical_positions": 142, "similar_positions": 189, "identity": "21.01%" }, { "cls_id": "homologset.agr.MGI:1352467", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P06211-1", "uniprot_id": "ESR1_RAT", "id": "P06211-1", "name": "Estrogen receptor", "aln": "MTMTLHTKASGMALLHQIQGNELEPLNRPQLKMPMERALGEVYVDNSKPAVFNYPEGAAYEFNAAAAAAAAGASAPVYGQSSITYGPGSEAAAFGANSLGAFPQLNSVSPSPLMLLHPPPHVSPFLHPHG------HQVPYYLENEPS---AYAVRDTGPPAFYRSNSDNRRQNGRERLSSSSEKGNMIMESAKETRYCAVCNDYASGYHYGVWSCEGCKAFFKRSIQGHNDYMCPATNQCTIDKNRRKSCQACRLRKCYEVGMMKGGIRKDRRGGRMLKHKRQRDDLEGRNEMGTSGDMRAANLWPSPLVIKHTKKN--SPALSLTADQMVSALLDAEPPLIYSEYDPSRPFSEASMMGLLTNLADRELVHMINWAKRVPGFGDLNLHDQVHLLECAWLEILMIGLVWRSMEHPGKLLFAPNLLLDRNQGKCVEGMVEIFDMLLATSSRFRMMNLQGEEFVCLKSIILLNSGVYTFLSSTLKSLEEKDHIHRVLDKINDTLIHLMAKAGLTLQQQHRRLAQLLLILSHIRHMSNKGMEHLYNMKCKNVVPLYDLLLEMLDAHRLHAP--ASRMGVPPEEPSQSQLTTTSSTSAHSLQTYYIPPEAEGFPNTI----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P19785-1", "uniprot_id": "ESR1_MOUSE", "id": "P19785-1", "name": "Estrogen receptor", "aln": "MTMTLHTKASGMALLHQIQGNELEPLNRPQLKMPMERALGEVYVDNSKPTVFNYPEGAAYEFNAAAAAAAA-ASAPVYGQSGIAYGPGSEAAAFSANSLGAFPQLNSVSPSPLMLLHPPPQLSPFLHPHG------QQVPYYLENEPS---AYAVRDTGPPAFYRSNSDNRRQNGRERLSSSNEKGNMIMESAKETRYCAVCNDYASGYHYGVWSCEGCKAFFKRSIQGHNDYMCPATNQCTIDKNRRKSCQACRLRKCYEVGMMKGGIRKDRRGGRMLKHKRQRDDLEGRNEMGASGDMRAANLWPSPLVIKHTKKN--SPALSLTADQMVSALLDAEPPMIYSEYDPSRPFSEASMMGLLTNLADRELVHMINWAKRVPGFGDLNLHDQVHLLECAWLEILMIGLVWRSMEHPGKLLFAPNLLLDRNQGKCVEGMVEIFDMLLATSSRFRMMNLQGEEFVCLKSIILLNSGVYTFLSSTLKSLEEKDHIHRVLDKITDTLIHLMAKAGLTLQQQHRRLAQLLLILSHIRHMSNKGMEHLYNMKCKNVVPLYDLLLEMLDAHRLHAP--ASRMGVPPEEPSQTQLATTSSTSAHSLQTYYIPPEAEGFPNTI----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P03372-1", "uniprot_id": "ESR1_HUMAN", "id": "P03372-1", "name": "Estrogen receptor", "aln": "MTMTLHTKASGMALLHQIQGNELEPLNRPQLKIPLERPLGEVYLDSSKPAVYNYPEGAAYEFNAAAAANAQ-----VYGQTGLPYGPGSEAAAFGSNGLGGFPPLNSVSPSPLMLLHPPPQLSPFLQPHG------QQVPYYLENEPS---GYTVREAGPPAFYRPNSDNRRQGGRERLASTNDKGSMAMESAKETRYCAVCNDYASGYHYGVWSCEGCKAFFKRSIQGHNDYMCPATNQCTIDKNRRKSCQACRLRKCYEVGMMKGGIRKDRRGGRMLKHKRQRDDGEGRGEVGSAGDMRAANLWPSPLMIKRSKKN--SLALSLTADQMVSALLDAEPPILYSEYDPTRPFSEASMMGLLTNLADRELVHMINWAKRVPGFVDLTLHDQVHLLECAWLEILMIGLVWRSMEHPGKLLFAPNLLLDRNQGKCVEGMVEIFDMLLATSSRFRMMNLQGEEFVCLKSIILLNSGVYTFLSSTLKSLEEKDHIHRVLDKITDTLIHLMAKAGLTLQQQHQRLAQLLLILSHIRHMSNKGMEHLYSMKCKNVVPLYDLLLEMLDAHRLHAP--TSRGGASVEETDQSHLATAGSTSSHSLQKYYITGEAEGFPATV----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P57717-1", "uniprot_id": "ESR1_DANRE", "id": "P57717-1", "name": "Estrogen receptor", "aln": "----MYPKEE------HSAGGISSSVN---------------YLDG----AYEYPN-PTQTFGTSSPAEPA----------SVGYYPAP-----PDPHEEHLQTLGGGSSSPLMFAPSSPQLSPYLSHHGGHHTTPHQVSYYLDSSSSTVYRSSVVSSQQAAVGLCEELCSATDRQELYTGSRAAG--GFDSGKETRFCAVCSDYASGYHYGVWSCEGCKAFFKRSIQGHNDYVCPATNQCTIDRNRRKSCQACRLRKCYEVGMMKGGIRKDR-GGRSVRRERRRSSNEDRDKSSSDQCSRAGVRTTGPQDKRKKRSGGVVSTLCMSPDQVLLLLLGAEPPAVCSRQKHSRPYTEITMMSLLTNMADKELVHMIAWAKKVPGFQDLSLHDQVQLLESSWLEVLMIGLIWRSIHSPGKLIFAQDLILDRSEGECVEGMAEIFDMLLATVARFRSLKLKLEEFVCLKAIILINSGAFSFCSSPVEPLMDNFMVQCMLDNITDALIYCISKSGASLQLQSRRQAQLLLLLSHIRHMSNKGMEHLYRMKCKNRVPLYDLLLEMLDAQRFQSSGKVQRVWSQSEKNPPSTPTTSSSSSNNSPRGGAAAIQSNGACHSHSPDP", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ::.* . : *. ..:* *:*. .::**: .: *.:::.* . .: * *.. : *.. *.****: ..*::**:* ** :**.***:...* :* .: .*. :. . :* :.: * ::*.****:****.******************************:**********:**************************** *** ::::*:*.. *.*.: .: **. ..* ::.:.. :*.::.**:: **.**** : *. . :**::* :**.****:**:****** ***:**** **.*****:***.:***:*****:***:. ****:** :*:***.:*:*****.********* :*** ::*: *******:***:***.::* **.::.* :: :: :**:*.*:**: ::*:* :** * :* *****:**************** ***** *************:*:::. ..* *: : :*:.*:* :* : . :::* : ", "identical_positions": 280, "similar_positions": 165, "identity": "45.38%" }, { "cls_id": "homologset.agr.MGI:1352474", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q1KMU0-1", "uniprot_id": "Q1KMU0_RAT", "id": "Q1KMU0-1", "name": "", "aln": "---------------------------------------------------------------------------------------------MAFKVLPEDRTVLFAAILLVGHLSCKASCETGDCRQQEFKDRSGNCVLCKQCGPGMELSKECGFGYGEDAQCVPCRPHRFKEDRGFQKCKPCVDCALVNRFQRANCSHTSDAVCGDCLPGFYRKTKLVGFQDMECVPCGDPPPPYEPHCTSKVNLVKISSTVSSPRDTALAAVICSALATVLLALLILCVIYCKRQFMEKKPSWSLRSQDIQYNGSELSCFDQPQLRHCAHRACCQYHRDSVQTYGPVHLIPPLCCEEARSSARAALGCGLHSTATLQERNTASVGDAMPVFFGSVSRSICAEFSDAWPLMQNPLGGD-SSLCDSYPELTGEDINSLNPENESSTSVDSNGGQDLAGAAAPDS--SGDFSENTDSPRYGDADTVWEQTLAQDAQRTPSREGWEASENLNLATSTAFQDA------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9JLL3-1", "uniprot_id": "TNR19_MOUSE", "id": "Q9JLL3-1", "name": "Tumor necrosis factor receptor superfamily member 19", "aln": "---------------------------------------------------------------------------------------------MALKVLPLHRTVLFAAILFLLHLACKVSCETGDCRQQEFKDRSGNCVLCKQCGPGMELSKECGFGYGEDAQCVPCRPHRFKEDWGFQKCKPCADCALVNRFQRANCSHTSDAVCGDCLPGFYRKTKLVGFQDMECVPCGDPPPPYEPHCTSKVNLVKISSTVSSPRDTALAAVICSALATVLLALLILCVIYCKRQFMEKKPSWSLRSQDIQYNGSELSCFDQPRLRHCAHRACCQYHRDSAPMYGPVHLIPSLCCEEARSSARAVLGCGLRSPTTLQERNPASVGDTMPAFFGSVSRSICAEFSDAWPLMQNPLGGD-SSLCDSYPELTGEDTNSLNPENESAASLDSSGGQDLAGTAALES--SGNVSESTDSPRHGDTGTVWEQTLAQDAQRTPSQGGWEDRENLNLAMPTAFQDA------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9NS68-1", "uniprot_id": "TNR19_HUMAN", "id": "Q9NS68-1", "name": "Tumor necrosis factor receptor superfamily member 19", "aln": "---------------------------------------------------------------------------------------------MALKVLLEQEKTFFTLLVLLGYLSCKVTCESGDCRQQEFRDRSGNCVPCNQCGPGMELSKECGFGYGEDAQCVTCRLHRFKEDWGFQKCKPCLDCAVVNRFQKANCSATSDAICGDCLPGFYRKTKLVGFQDMECVPCGDPPPPYEPHCASKVNLVKIASTASSPRDTALAAVICSALATVLLALLILCVIYCKRQFMEKKPSWSLRSQDIQYNGSELSCFDRPQLHEYAHRACCQCRRDSVQTCGPVRLLPSMCCEEACSPNPATLGCGVHSAASLQARNAGPAGEMVPTFFGSLTQSICGEFSDAWPLMQNPMGGDNISFCDSYPELTGEDIHSLNPELESSTSLDSNSSQDLVGGAVPVQSHSENFTAATDLSRYNN--TLVESASTQDALTMRSQLDQESGAVIHPATQTSLQVRQRLGSL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AC58HB26-1", "uniprot_id": "A0AC58HB26_DANRE", "id": "A0AC58HB26-1", "name": "", "aln": "MKAFLHQTRADPITHTHTHSPLSGARRRTFLFLFLVSECLAFGIYSWNGRSDYRNHTAGFHLRSCSSSAGPGQTLDLQPLLSADHRRTTHRVRMPQAQILSRFPLQRILILPLCVLFAVMAEERRDCREQEYKDKFGSCIPCRQCDAGQELSKECGFGYGEDAQCVPCRASRFKEDRSLQKCKPCLDCSLLNRFQKGNCSTTNNAVCGDCLPGFYRKTKLRGFQDMECIPCGDPPPPYETHCMGRVNLVPLPSTVSSPRDMALAAVICSALATVLLALFILCVIYCKRQLLEKKP-VSMRAHEGPFLGSELSCLDR-RVLELSQRPCCHCTHRSGQTCGGVQLVSSVCCEDVWSQNRRRDAPAFHSHCRISDN-----GRLTNESVGSQTDMACAP-DEVWPLVQ-----------------SRRTTDSLQTNQRCSSCEEDE-----------------------------------EEVQISDQRTAEEPEDASHRPLIQQTTDTEG---------", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *. : :: : * . : * ***:**::*: *.*: *.**..* *****************.** ***** .:****** **:::****:.*** *.:*:************** *******:**********.** .:**** :.**.***** *****************:**********::**** *:*::: : ******:*: :: . ::*.**: : * * *:*:..:***:. * . ..:* :. . * .** : *. .:.***:* : . .**:.: ..::. :.. *.. .* . . . :: : * ", "identical_positions": 165, "similar_positions": 96, "identity": "31.85%" }, { "cls_id": "homologset.agr.MGI:1352480", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "F1M9B2-1", "uniprot_id": "F1M9B2_RAT", "id": "F1M9B2-1", "name": "Insulin-like growth factor-binding protein 7", "aln": "MFLPVLESEDVGRGLSRSGLASVLGMGRARRGSEDAHDGGRPDPRRAEPGGQQADSPPRGGPPRSAGRGSGFKGWPPGPGLLTCALASSHPIMERS-PRALLLGAAGLLLLLLPLSSSSSSDACGPCVPASCPALPPLGCPLGETRDACGCCPVCARGEGEPCGGGAAGRGHCAPGMECVKSRKRRKGKAGAAAGGPATLAVCVCKSRYPVCGSDGVTYPSGCQLRAASLRAESRGEKAITQVSKGTCEQGPSIVTPPKDIWNITGAKVYLSCEVIGIPTPVLIWNKVKRDHSGVQRTELLPGDRENLAIQTRGGPEKHEVTGWVLVSPLSKEDTGEYECHASNSQGQASASAKITVVDAIHEIPVKKGEGAQL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q61581-1", "uniprot_id": "IBP7_MOUSE", "id": "Q61581-1", "name": "Insulin-like growth factor-binding protein 7", "aln": "--------------------------------------------------------------------------------------------MERP-PRALLLGAAGLLLLLLPLSSSSSSDACGPCVPASCPALPRLGCPLGETRDACGCCPVCARGEGEPCGGGAAGRGHCAPGMECVKSRKRRKGKAGAAAGGPATLAVCVCKSRYPVCGSNGITYPSGCQLRAASLRAESRGEKAITQVSKGTCEQGPSIVTPPKDIWNVTGAKVFLSCEVIGIPTPVLIWNKVKRDHSGVQRTELLPGDRENLAIQTRGGPEKHEVTGWVLVSPLSKEDAGEYECHASNSQGQASAAAKITVVDALHEIPLKKGEGAQL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q16270-1", "uniprot_id": "IBP7_HUMAN", "id": "Q16270-1", "name": "Insulin-like growth factor-binding protein 7", "aln": "--------------------------------------------------------------------------------------------MERPSLRALLLGAAGLLLLLLPLSSSSSSDTCGPCEPASCPPLPPLGCLLGETRDACGCCPMCARGEGEPCGGGGAGRGYCAPGMECVKSRKRRKGKAGAAAGGPGVSGVCVCKSRYPVCGSDGTTYPSGCQLRAASQRAESRGEKAITQVSKGTCEQGPSIVTPPKDIWNVTGAQVYLSCEVIGIPTPVLIWNKVKRGHYGVQRTELLPGDRDNLAIQTRGGPEKHEVTGWVLVSPLSKEDAGEYECHASNSQGQASASAKITVVDALHEIPVKKGEGAEL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1PIC1-1", "uniprot_id": "A0A8M1PIC1_DANRE", "id": "A0A8M1PIC1-1", "name": "", "aln": "------------------------------------------------------------------------------------------------------MLCVLVLALLASASAQRLSRGCGSCDRTQCAPLPAQGCSSGTLRDSCGCCELCAAAEGEPCGGRGVSARRCGSGLECVKPDKKSKS------------GICVCKSGVPVCGTDGRNYNSGCALRAASARALQEKQPEIRVHNTGRCAQGPEIVTPPGEVWNITGSQVFLSCEAIGVPTPVLTWRKVS---GGSEKPVPLPGDKDNLAVQTRGGPEKHQVTGWVLISPLTKAEDGSYECHASNTQGEASAVGSIHVVESISDIPVQMVKDSEL", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : .. :* ** . *:. * **.* :.*..** ** * **:**** :** .******* ... *..*:****. *: *. .:***** ****::* .* *** ***** ** .. : * ..* * ***.***** ::**:**::*:****.**:***** *.**. * ::. ****::***:*********:******:***:* : *.*******:**:*** ..* **::: :**:: :.::*", "identical_positions": 134, "similar_positions": 70, "identity": "35.83%" }, { "cls_id": "homologset.agr.MGI:1352481", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "F7FG21-1", "uniprot_id": "F7FG21_RAT", "id": "F7FG21-1", "name": "", "aln": "MCRKEASPALHAHKSGNNQRSAGSGGTGTGQAAPVSMEPAGLCGFCPAGEAVPARYTCPRCNAPYCSLRCYR--AHGACAEDFYRDQVLRELRGRNASPS------RLAGALRRLREQRE--AEDEPEETGLRPGTRP-GGLSGLWERLAPAEKAAFERLLSRGEAGRLLPPWR---------PWWWGRGTGPRFLEELDDDASRDLAEPELLPARTGLESVDDAAAAGEPLAE----DSSVARPPAMPARIPALASLSRSPTSPLVRFQLPNVLFAYAHTLALYHGGDDDALLSDFCATLLDVSGALGTQQVFHSTEEALQ-AAAHVLEAGEHPPGPLGTRGAMQEVARILLGEGPINQKGYTLIALGHLAQTLGRARKQ----------------------------AALTPLALDCARAHRAHAVTVEEMATLTGELERLWGGPVPPAPRILIEELPG", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9QY66-1", "uniprot_id": "ZNHI2_MOUSE", "id": "Q9QY66-1", "name": "Zinc finger HIT domain-containing protein 2", "aln": "------------------------------------MEPAGLCGFCPAGEALPARYTCPRCNAPYCSLRCYR--AHGACAEDFYRDQVLRELRGRSASPS------RLAGALRRLREQRE--AEDEPEEAGLGPGARP-GGLSGLWERLTPAEKAAFERLLSRGEAGRLLPPWR---------PWWWGRGTGPRLLEELDHAANRDLAEPEPAPARTALQSGDDAAAA-EPFAE----DSCAARPLALPARIPALASLSRSPASPLVRFQLPNVLFAYAHTLALYHGGDDDALLSDFCATLLDVSGALGAQQVFGSTEEALQ-AAAHVLEAGEHPPGPLGTRGAMQEVARILLGEGPVNQKGYTLTALGHLAQTLGRARKQAVIGGERDRLYRARKKCQFLLAWTNENEAALTPLALDCARAHRAHAVTAEEMATLTGELERLWGGPVPPTPRTLIEELPG", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9UHR6-1", "uniprot_id": "ZNHI2_HUMAN", "id": "Q9UHR6-1", "name": "Zinc finger HIT domain-containing protein 2", "aln": "------------------------------------MEPAGPCGFCPAGEVQPARYTCPRCNAPYCSLRCYR--THGTCAENFYRDQVLGELRGCSAPPS------RLASALRRLRQQRE--TEDEPGEAGLSSGPAP-GGLSGLWERLAPGEKAAFERLLSRGEAGRLLPPWR---------PWWWNRGAGPQLLEELDNAPGSDAAELELAPARTPPDSVKDASAAEPAAAERVLGDVPGACTPVVPTRIPAIVSLSRGPVSPLVRFQLPNVLFAYAHTLALYHGGDD-ALLSDFCATLLGVSGALGAQQVFASAEEALQ-AAAHVLEAGEHPPGPLGTRGAMHEVARILLGEGPTNQKGYTLAALGDLAQTLGRARKQAVAREERDHLYRARKKCQFLLAWTNENEAALTPLALDCARAHQAHAVVAEEVAALTGELERLWGGPVPPAPRTLIEELPS", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q7KSA2-1", "uniprot_id": "Q7KSA2_DROME", "id": "Q7KSA2-1", "name": "HIT-type domain-containing protein", "aln": "-----------------------------------MSEADEKCHFC---REVSFKYTCPKCNALYCSVGCYKSKEHLKCSEAFYKSCIQDELTQNTVTQESQEDMRKIYDILKRMRETDSGFNPQEFDTDGLENSLDSDGGEEGESEEDEAEENVTEGDILDEDLEEDIATRLKGVDINDADEVWSRLTTEEQDEFQKLITNGDIMKLMPDYKPWWIKPKNSKIVIIPTPEEAAK-----KESRVPEIFGSIAKFSDICKKTPSPCLHYNLWNILSAYAC-VARFFGGEQRTNASEAVAHLVNLSATLKYGTNFEDAEDAIVSVEMEAITTGNGPAGAAAVGSAAGGANFLVDNREQLQQDARQLMATKEHKLAALSDVLYLLQQT----------------------KAISRRKNTQEAEFQKLFALASGSVQLDRTKLAQLVRKIEFMLSYVAREEVL-", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *. * ** . . :****:*** ***: **: * *:* **:. : ** ... . :: . *:*:*: . :* ** . . ** .* *. . *:.: :*... : . : * :::* . : * .. . . . * : : *. : .:.: . ** ::::* *:* *** :* :.**:: : *: * *:.:*.:* * .:*:*: . ..: :*: *.*. .. .* . :: .. :*.. * * . : * : *. :: .*:. .: :* :* . **: ", "identical_positions": 73, "similar_positions": 112, "identity": "15.84%" }, { "cls_id": "homologset.agr.MGI:1352483", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I6AGZ4-1", "uniprot_id": "A0A8I6AGZ4_RAT", "id": "A0A8I6AGZ4-1", "name": "MAX gene-associated protein", "aln": "--MEEKQQIILANQDGGTVTGAAP------TFFVILKQPGNGKTDQG-----------------ILVTNRDARALLSRESSPGKSKEKICLPADCTVGKITVTLDNNSMWNEFHNRSTEMILTKQGRRMFPYCRYWITGLDSNLKYILVMDISPVDSHRYKWNGRWWEPSGKAEPHILGRVFIHPESPSTGHYWMHQPVSFYKLKLTNNTLDQEGHIILHSMHRYLPRLHLVPAEKAT-EVIQLNGPGVHTFTFPQTEFFAVTAYQNIQITQLKIDYNPFAKGFRDDGLSSKPQRDGKQRNSSDQEGNSVSSSPGHRVR----LTEGEGSEIHSGDFDPVLRGHETSSLGLEKAPNNVKQDFLGFMN-TDSTH-EVPQLKREISES-HVSSFEENSQISSPLNPNGNFNVVIKEEPLDDYDYELGECPEGITVKQEETDEETDVYSNSDDDPILEKQLKRHNKVDNLEADHSSYK-WLPNSP-GVAKAKMFKLDAGKMPVVYLEPCAVTKSTVKISELPDNMLSTSRKDKS-MLAELEYLPAYIENSDETGFCLSKDSENSLRKHSSDLRMVQKYTLLKEPHWKYPDIFDSSSTEKTHDSSKGSTEDSFSGKEDLGKKRTTMLKMAIPSKTVNASQSASPNTPGKRGRPRKLRLSKAGRPPKNTGKSLTASKNIPVGPGNTFPDVKPDLEDVDGVLFVSFESKEALDIHAVDGTTEEPSSVQTTTTNDSGSRTRISQLEKELIEDLKSLRHKQVIHPALQEVGLKLNSVDPTMSIDLKYLGVQLPLAPATSFPLWNVTGTNPASPDAGFPFVSRTGKTNDFTKIKGWRGKFHNASASRNEGGNSETSLKNRSAFCSDKLDEYLENEGKLMETSMGFSSNAPTAPTSPVVYQLPTKSTSYVRTLDSVLKKQSTISPSTSHSVKPHSVTTASRKTKAQNKQTTVSGRTKSSYKSILPYPVSPKQKNSHVSPGDKITKNSLSSASDNQVTNLVVPSIDESAFPKQISLRQAQQQHIQQQGTRPPGLSKSQVKLMDLEDCALWEGKPRTYITEERADVSLTTLLTAQASLKTKPIHTIIRKRAPPCNNDFCRLGCVCSSLALEKRQPAHCRRPDCMFGCTCLKRKVVLVKGGSKTKHLHKKAANRDPLFYDTLGEGGREGGGGVREDEEQLKEKKKRKKLEYTVCEAEPEQPVRHYPLWVKVDGEVDPEPVYIPTPSVIEPIKPLVLPQPDASSTTIKGKLTPGIKPTRAYTPKPNPVIREEDKDPVYLYFESMMTCARVRVYERKKDEQRQLSPPLSPSSSFQQQSSCYSSPENH-ATKELDSEQ-TLKQLICDLEDDSDKSQEKTWKSSCNEGESSSTSYVHQRSPGGPTKLIEIISDCNWEEDRNKILSILSQHINSNMPQSLKVGSFIIELASQRKCRGEKTPPVYSSRVKISMPSSQDQDDMAEKSGSETPDGPLSPGKMDDISPVQTDALDSVRERLHGGKGLPFYAGLSPSGKLVAYKRKPSSTTSGLIQVNGKSYPQAKLLLGQMGALHPANRLAAYITGRLRPSVLDLSTLSTVISKVASNAKVAASRKPRTLLPSTSNSKMASS-GPTTNRSGKNLKAFVPAKRPIAARPSPGGVFTQFVMSKVGALQQKIPGVRTPQPLTGPQKFSIRPSPVMVVAPVVSSEQVQVCSTVTAAVTTS-PQVVLENVTAVPSLTANSDMGAKEATYSSSASTAGVVEISETNNTTPVTSTQSTATVNLTKTTGITTSPVASVSFPKPLVASP-TITLPVASTASTSIVMVTTAASSSVVTTPTSSLSSVPIILSGINGSPPVSQRPENAPQIPVTTPQISPNNVKRTGPRLLLIPVQQGSPTLRPIPNPQLQGQRMVLQPVRSPSGMNLFRHPNGQIVQLLPLHQIRGSNTQPSLQPVVFRNPGSVVGIRLPTPCKSSETPSS-SSSSAFSVMSPVIQAVGSSPTVNVISQAPSLLSSGSSFVSQAGTLTLRISPPETQNLASKTASESKITPSTGGQPVGTASLIPLQSGSFALLQLPGQKPVPNSVLQHVASLQIKKESQNTDQKDESNSIKREKETKKALSSKDEVVDPEANIMKQNSGIIASEDTFNNSLDDRGDLLDEESLRED----TRPYEYSYSTGSHTDED-KDGDEESGNKNENSPKEKQTVPEVRAGSENINIMTLQNVRKVRPQKYVEVKVEQQQGS----ENPDDFLVLSKEESKFELSGSQVKEQKSNSQTEAK-KDCEDSLGKDSLRERWRKHLKGPLTHKYVGISQDFKKEADVQLFTEMKPCQDNS-----ERDISELLGKSGTIESGGIFKTEDGSWSGISSSAAFSIIPRRATKGRRGSRRFQGHFLLSKEHMKPKQQANGGRS-SADFTVLDLEDEDEEDENEKTDDSIDEIVDVVSGYQSEEVD-VEKNNYVDYIEDDE-QVDVETVEELSEEINFTYKKTTAAHTQSFRQQCHSLISADEKASEKSRKVSLISSKLKDDCWSDKPHKETEAFAYYRRTHTANERRRRGEMRDLFEKLKITLGLLHS-SKVSKSLILNRAFSEIQGLTDQADKLIGQKNLLSRKRSILIRKVSSLSGKTEEVVLKKLEYIYAKQQALEAQKRKKKMGSDEFGLSPRIS---------------TQLEGS-SSSVDLGQMFMSNRRGKPLILSRRRDQATENASPSDTPHSSANLVMTPQGQLLTLKGPLFSAPVVAVSPALLEAGLKPQVASSTMAQSENDDLFMMPRIVNVTSLAAEEDLGGMSGNKYLHEVPD--GKPALDHLRDVSGNEASSLKDTERISSRGNHRDSRMALGPTQVFLANKDSGFPHVPDVSTMQAAQEFIPKKMSGDLRGHRHKWKECELRGERLKSKESQFHKLKMKDLKDSSIEMELRKVASAIEEAALDPSELLTNMEDEDDTDETLTSLLN-----EIAFLNQQLNDD-SGLAELSGSLDTEFPGDAQQAFISKLAPGNRSAFQVGHLG--TGVKELPDVQEESES--ISPLLLHLEDDDFSENEKQLGDTASEPDVLKIVIDSEIKDSLVSH----RKSSDGGQSTSGLPAEPESVSSPPILHMKTGPENSS-TDTLWRPMPKLAPLGLKVANPPSDADGQSLKVMPALAPIAAKVGSVGHKMNTTGSDQEGRGSKMMPTLAPVVTKLGNSGVPSSSSGK", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A2AWL7-1", "uniprot_id": "MGAP_MOUSE", "id": "A2AWL7-1", "name": "MAX gene-associated protein", "aln": "--MEEKQQIILANQDGGTVTGGAP------TFFVILKQPGNGKTDQG-----------------ILVTNRDARALLSRESSPGKSKEKICLPADCTVGKITVTLDNNSMWNEFHNRSTEMILTKQGRRMFPYCRYWITGLDSNLKYILVMDISPVDSHRYKWNGRWWEPSGKAEPHILGRVFIHPESPSTGHYWMHQPVSFYKLKLTNNTLDQEGHIILHSMHRYLPRLHLVPAEKAT-EVIQLNGPGVHTFTFPQTEFFAVTAYQNIQITQLKIDYNPFAKGFRDDGLSSKPQREGKQRNSSDQEGNSVSSSPAHRVR----LTEGEGSEIHSGDFDPVLRGHEASSLSLEKAPHNVKQDFLGFMN-TDSTH-EVPQLKHEISESRIVNSFEDDSQISSPSNPNGNFNVVIKEEPLDDYDYELGECPEGITVKQEETDEETDVYSNSDDDPILEKQLKRHNKVDNLEADHPSYK-WLPNSP-GVAKAKMFKLDAGKMPVVYLEPCAVTKSTVKISELPDNMLSTSRKDKS-MLAELEYLPAYIENSDGTDFCLSKDSENSLRKHSPDLRIVQKYTLLKEPNWKYPDILDNSSTERIHDSSKGSTAESFSGKEDLGKKRTTMLKMAIPSKTVTASHSASPNTPGKRGRPRKLRLSKAGRPPKNTGKSLTAAKNIPVGPGSTFPDVKPDLEDVDGVLFVSFESKEALDIHAVDGTTEEPSSLQTTTTNDSGCRTRISQLEKELIEDLKSLRHKQVIHPALQEVGLKLNSVDPTVSIDLKYLGVQLPLAPATSFPLWNVTGTNPASPDAGFPFVSRTGKTNDFTKIKGWRGKFQNASASRNEGGNSEASLKNRSAFCSDKLDEYLENEGKLMETNIGFSSNAP---TSPVVYQLPTKSTSYVRTLDSVLKKQSTISPSTSHSVKPQSVTTASRKTKAQNKQTTLSGRTKSSYKSILPYPVSPKQKNSHVSQGDKITKNSLSSTSDNQVTNLVVPSVDENAFPKQISLRQAQQQHLQQQGTRPPGLSKSQVKLMDLEDCALWEGKPRTYITEERADVSLTTLLTAQASLKTKPIHTIIRKRAPPCNNDFCRLGCVCSSLALEKRQPAHCRRPDCMFGCTCLKRKVVLVKGGSKTKHFHKKAANRDPLFYDTLGEEGREGGG-VREDEEQLKEKKKRKKLEYTVCEAEPEQPVRHYPLWVKVEGEVDPEPVYIPTPSVIEPIKPLVLPQPDLSS-TTKGKLTPGIKPARTYTPKPNPVIREEDKDPVYLYFESMMTCARVRVYERKKEEQRQLSPPLSPSSSFQQQSSCYSSPENR-VTKELDSEQ-TLKQLICDLEDDSDKSQEKSWKSSCNEGESSSTSYVHQRSPGGPTKLIEIISDCNWEEDRNKILSILSQHINSNMPQSLKVGSFIIELASQRKCRGEKTPPVYSSRVKISMPSSQDQDDMAEKSGSETPDGPLSPGKMDDISPVQTDALDSVRERLHGGKGLPFYAGLSPSGKLVAYKRKPSSTTSGLIQV-------------------------------------------------ASNAKVAASRKPRTLLPSTSNSKMASS-GPATNRSGKNLKAFVPAKRPIAARPSPGGVFTQFVMSKVGALQQKIPGVRTPQPLTGPQKFSIRPSPVMVVTPVVSSEQVQVCSTVAAAVTTS-PQVFLENVTAVPSLTANSDMGAKEATYSSSASTAGVVEISETNNTTLVTSTQSTATVNLTKTTGITTSPVASVSFAKPLVASP-TITLPVASTASTSIVMVTTAASSSVVTTPTSSLSSVPIILSGINGSPPVSQRPENAPQIPVTTPQISSNNVKRTGPRLL---------------------------------------HPNGQIVQLLPLHQIRGSNAQPSLQPVVFRNPGSMVGIRLPAPCKSSETPSSSASSSAFSVMSPVIQAVGSSPTVNVISQAPSLLSSGSSFVSQAGTLTLRISPPETQNLASKTGSESKITPSTGGQPVGTASLIPLQSGSFALLQLPGQKPIPSSVLQHVASLQIKKESQSTDQKDETNSIKREEETKKALPSKDKALDSEANIMKQNSGIIASENTSNNSLDDGGDLLDEETLRED----ARPYEYSYSTGSHTDED-KDGDEDSGNKNQNSPKEKQTVPEVRAGSKNIDIMALQSIRSIRPQKCVKVKVEPQEGSDNP-ENPDDFLVLSKD-SKFELSGNQVKEQQSNSQAEAK-KDCEDSLGKDSLRERWRKHLKGPLTQKYIGISQNFNKEANVQFFTEMKPCQENS-----EQDISELLGKSGTIESGGVLKTEDGSWSGISSSAAFSIIPRRATKGRRGSRHFQGHLLLPREQMKPKQQTKDGRSSAADFTVLDLEDEDEED--EKTDDSLDEIVDVVSGYQSEEVD-VEKNNYVDYLEDDE-QVDVETIEELSEEINFPYKKTTATHTQSFKQQCHSHISADEKASEKSRKVSLISSKLKDDCWGDKPHKETEAFAYYRRTHTANERRRRGEMRDLFEKLKITLGLLHS-SKVSKSLILNRAFSEIQGLTDQADKLIGQKNLLSRKRSILIRKVSSLSGKTEEVVLKKLEYIYAKQQALEAQKRKKKLGSDEFCVSPRIG---------------TQLEGSSASSVDLGQMLMNNRRGKPLILSRKRDQATENASPSDTPHSSANLVMTPQGQLLTLKGPLFSGPVVAVSPALLEGGLKPQVASSTMSQSENDDLFMMPRIVNVTSLAAEEDLGGMSGNKYRHEVPD--GKP-LDHLRDIAGSEASSLKDTERISSRGNHRDSRKALGPTQVLLANKDSGFPHVADVSTMQAAQEFIPKNMSGDVRGHRYKWKECELRGERLKSKESQFHKLKMKDLKDSSIEMELRKVASAIEEAALHPSELLTNMEDEDDTDETLTSLLN-----EIAFLNQQLNDD-SGLAELSGSMDTEFSGDAQRAFISKLAPGNRSAFQVGHLG--AGVKELPDVQEESES--ISPLLLHLEDDDFSENEKQLGDTASEPDVLKIVIDPEIKDSLVSH----RKSSDGGQSTSGLPAEPESVSSPPILHMKTGPENSN-TDTLWRPMPKLAPLGLKVANPPSDADGQSLKVMPALAPIAAKVGSIGHKMNLAGIDQEGRGSKVMPTLAPVVPKLGNSGAPSSSSGK", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8IWI9-4", "uniprot_id": "MGAP_HUMAN", "id": "Q8IWI9-4", "name": "MAX gene-associated protein", "aln": "--MEEKQQIILANQDGGTVAGAAP------TFFVILKQPGNGKTDQG-----------------ILVTNQDACALASSVSSPVKSKGKICLPADCTVGGITVTLDNNSMWNEFYHRSTEMILTKQGRRMFPYCRYWITGLDSNLKYILVMDISPVDNHRYKWNGRWWEPSGKAEPHVLGRVFIHPESPSTGHYWMHQPVSFYKLKLTNNTLDQEGHIILHSMHRYLPRLHLVPAEKAV-EVIQLNGPGVHTFTFPQTEFFAVTAYQNIQITQLKIDYNPFAKGFRDDGLNNKPQRDGKQKNSSDQEGNNISSSSGHRVR----LTEGQGSEIQPGDLDPLSRGHETSGKGLEKTSLNIKRDFLGFMD-TDSALSEVPQLKQEISECLIASSFEDDSRVASPLDQNGSFNVVIKEEPLDDYDYELGECPEGVTVKQEETDEETDVYSNSDDDPILEKQLKRHNKVDNPEADHLSSK-WLPSSPSGVAKAKMFKLDTGKMPVVYLEPCAVTRSTVKISELPDNMLSTSRKDKSSMLAELEYLPTYIENSNETAFCLGKESENGLRKHSPDLRVVQKYPLLKEPQWKYPDISDSISTERILDDSKDSVGDSLSGKEDLGRKRTTMLKIATAAKVVNANQNASPNVPGKRGRPRKLKLCKAGRPPKNTGKSLISTKNTPVSPGSTFPDVKPDLEDVDGVLFVSFESKEALDIHAVDGTTEESSSLQASTTNDSGYRARISQLEKELIEDLKTLRHKQVIHPGLQEVGLKLNSVDPTMSIDLKYLGVQLPLAPATSFPFWNLTGTNPASPDAGFPFVSRTGKTNDFTKIKGWRGKFHSASASRNEGGNSESSLKNRSAFCSDKLDEYLENEGKLMETSMGFSSNAP---TSPVVYQLPTKSTSYVRTLDSVLKKQSTISPSTSYSLKPHSVPPVSRKAKSQNRQATFSGRTKSSYKSILPYPVSPKQKYSHVILGDKVTKNSSGIISENQANNFVVPTLDENIFPKQISLRQAQQQQQQQQGSRPPGLSKSQVKLMDLEDCALWEGKPRTYITEERADVSLTTLLTAQASLKTKPIHTIIRKRAPPCNNDFCRLGCVCSSLALEKRQPAHCRRPDCMFGCTCLKRKVVLVKGGSKTKHFQRKAAHRDPVFYDTLGEEAREEEEGIREEEEQLKEKKKRKKLEYTICETEPEQPVRHYPLWVKVEGEVDPEPVYIPTPSVIEPMKPLLLPQPEVLSPTVKGKLLTGIKSPRSYTPKPNPVIREEDKDPVYLYFESMMTCARVRVYERKKEDQRQPSSSSSPSPSFQQQTSCHSSPENHNNAKEPDSEQQPLKQLTCDLEDDSDKLQEKSWKSSCNEGESSSTSYMHQRSPGGPTKLIEIISDCNWEEDRNKILSILSQHINSNMPQSLKVGSFIIELASQRKSRGEKNPPVYSSRVKISMPSCQDQDDMAEKSGSETPDGPLSPGKMEDISPVQTDALDSVRERLHGGKGLPFYAGLSPAGKLVAYKRKPSSSTSGLIQV-------------------------------------------------ASNAKVAASRKPRTLLPSTSNSKMASSSGTATNRPGKNLKAFVPAKRPIAARPSPGGVFTQFVMSKVGALQQKIPGVSTPQTLAGTQKFSIRPSPVMVVTPVVSSEPVQVCSPVTAAVTTTTPQVFLENTTAVTPMTAISDVETKETTYSSGATTTGVVEVSETNTSTSVTSTQSTATVNLTKTTGITT-PVASVAFPKSLVASPSTITLPVASTASTSLVVVTAAASSSMVTTPTSSLGSVPIILSGINGSPPVSQRPENAAQIPVATPQVSPNTVKRAGPRLLLIPVQQGSPTLRPVSNTQLQGHRMVLQPVRSPSGMNLFRHPNGQIVQLLPLHQLRGSNTQPNLQPVMFRNPGSVMGIRLPAPSKPSETPPSSTSSSAFSVMNPVIQAVGSSSAVNVITQAPSLLSSGASFVSQAGTLTLRISPPEPQSFASKTGSETKITYSSGGQPVGTASLIPLQSGSFALLQLPGQKPVPSSILQHVASLQMKRESQNPDQKDETNSIKREQETKKVLQSEGEAVDPEANVIKQNSGAATSEETLNDSLEDRGDHLDEECLPEEGCATVKPSEHSCITGSHTDQDYKDVNEEYGARNRKSSKEKVAVLEVRTISEKASNKTVQNLSKVQHQKLGDVKVEQQKGFDNPEENSSEFPVTFKEESKFELSGSKVMEQQSNLQPEAKEKECGDSLEKD--RERWRKHLKGPLTRKCVGASQECKKEADEQLIKETKTCQENSDVFQQEQGISDLLGKSGITEDARVLKTECDSWSRISNPSAFSIVPRRAAKSSRGNGHFQGHLLLPGEQIQPKQEKKGGRS-SADFTVLDLEEDDEDD-NEKTDDSIDEIVDVVSDYQSEEVDDVEKNNCVEYIEDDEEHVDIETVEELSEEINVAHLKTTAAHTQSFKQPSCTHISADEKAAERSRKAPPIPLKLKPDYWSDKLQKEAEAFAYYRRTHTANERRRRGEMRDLFEKLKITLGLLHS-SKVSKSLILTRAFSEIQGLTDQADKLIGQKNLLTRKRNILIRKVSSLSGKTEEVVLKKLEYIYAKQQALEAQKRKKKMGSDEFDISPRIS---------------KQQEGSSASSVDLGQMFINNRRGKPLILSRKKDQATENTSPLNTPHTSANLVMTPQGQLLTLKGPLFSGPVVAVSPDLLESDLKPQVAGSAVALPENDDLFMMPRIVNVTSLATEGGLVDMGGSKYPHEVPD--SKP-SDHLKDTVRNEDNSLEDKGRISSRGN-RDGRVTLGPTQVFLANKDSGYPQIVDVSNMQKAQEFLPKKISGDMRGIQYKWKESESRGERVKSKDSSFHKLKMKDLKDSSIEMELRKVTSAIEEAALDSSELLTNMEDEDDTDETLTSLLN-----EIAFLNQQLNDDSVGLAELPSSMDTEFPGDARRAFISKVPPGSRATFQVEHLG--TGLKELPDVQGESDS--ISPLLLHLEDDDFSENEKQLAEPASEPDVLKIVIDSEIKDSLLSN----KKAIDGGKNTSGLPAEPESVSSPPTLHMKTGLENSNSTDTLWRPMPKLAPLGLKVANPSSDADGQSLKVMPCLAPIAAKVGSVGHKMNLTGNDQEGRESKVMPTLAPVVAKLGNSGASPSSAGK", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M2B5I7-1", "uniprot_id": "A0A8M2B5I7_DANRE", "id": "A0A8M2B5I7-1", "name": "", "aln": "MADTEKQGAMVLHEEGVTAPTLAPPTTTPPSIFVVLKQLQSSDSGNDKANLMAISEANKMGKSSIGTTVAGIQPTSSTFADTNSTTPSENLPADARCRGITVTLDNNNMWNEFHRCKTEMILTKQGRRMFPYCRFRLSGMEPFQNYVLAMDIKPADNCRYKWSGKGWEPNGKAEPHIS-RLFVHPESPASGLHWMQYPVSFYRLKLCN-TLDQEGHIILHSMHRYLPQIHIIPADKVSKDILILDRPNVVTLSFAQTEFFAVTAYQNLCITQLKIDYNPFAKGFREDAVNARSSKAKNGLSTDETESELKLSKEMTTLNNLKTLFMKRKASVKVNVNQNVPNPTNGENKVVNGAAPAVDTNVQSLCNKKRPSSLAFSDFIKGAHVKVKRLSLENINKTGGATEPSTACTSKQKEAADISSITEN-----SLQVDQKDGNGAGDVLRCESTDTSLKTGVLKANEIKKEIDEHSADKNTLKSSDQNLSCSDEKKMETVSSLSTEAKPEAQMKKTLPHKRPERVPLPLLAKFLK---QRRPILPKPVSHSSLSDSEKSCEPAQTSESSSVLMSFVPCVTTNLDSQPAVTSLSQTVTSSTTDANNMTSLSTTLS-------YSSTTVPLIPSETQLCDRFSASPVGSDPFSAPNTTSPSKPNSNPALDISNNTDAIFTPDHDNTLRSQSDISSDSTCDVVHDSCPPTVNTDTVETPVVPSPTSVFDVPSSTDNDMNSYQDINSMPDVAEGDSIS-DCLLDSSTGSCPEFFSEEIPQNTLFTNEESLSLPLDDAS-SPAFSLPSPAPSSPDPFPPSLFCDRPVPPRKALDSFPERLLDCTAAS-----------ARDPFPLGFFNDGREPPRQIFDLPE-----------RPLIGTVASR-ESLSSSVNNGPEHPMETGDLFSQSHCPDRANSLNDLESAASCETAVSDNSISKPTKPSPHGSSCKKYKGKQKKVGMLKLGEDSEVFDGPVPVPLQPSLEDVEGQLFVSFMSKKALRIHLGD------DDDDKPETAQENTDNPDGNNEEKIEKKIEGLEKVLLHDLKFMKNRQVIHPVLQEVGLKLNLLDVTLEIDLQYLGVQLPIPPPALSPEETS------SQAQFVSRTGKTSDFTQIKGWR-----DKFAPSASLSEGVSSTDAGQSNLSAFCSDMLDEYLASEGKLIDERAASLSQADCTPVAYQLPTKSTSYVRTLDSVLKKQVPAILTPTTNKVKPTFKSKVENKSK-KPLKPGKGKQTKPVISDAKPLCTKKPQQNKKYKSRKEFKSPEKPDVAEVPASNTTPMAEDS-GSTSSTCAGGRSPGLPKTLVKLLDVEDGAVWEG-------RHRSYITEER--AAIALATLVTAEGASTGSADAIRIIRRRAPPCLNVFCRLGCVCASLVHLRRHHHCGKPQCMLGCSCLRRKVVALKTPKQEEGTADDSD----PQGMSEENKAKWRKKNKMRKTYVLTD--PEIAPEPAKRVSTLWDRTRGNFDKEVLYCP------------------------------------------------------PPPRSPQPQLLSQELQHDLES-------------FLSPSKQKRVEERNLSTSEDNIEINLTCARSRPFHSNCHDKPKADDNKHHIS---------QVSTPDIEEGELVPLNLSGPAKRLEMMSECTWTSIDMRNNVMRIVCEHMAQDRLNQPFWIGKYFIKPVSKTLEEEENGSVEIYKVIISQPMEKKTENEKVTQKEEELEKHVKTSEVKGLPFLSKCCPAGLLKAEK--------------------KSPDAPGQIMVNGKHYPQAKLELG---------------------------------------------HMGALHPANRLAAYITGRICPTVSAITKPPVTTVPSSTLTTVSKVTCTPAS--TTTSVSKSLAARSPLEKVFSQFVVNQINSQNVSNTSTSHLQPSVPKIVIPSPLLMIGKEAGAPSVALSSLKAGLVTKVSESSNSTGSTTIPTVSNVQVPAFTILTKSPSLPLGGSTLTTTTSASSPGLTSPAKKTVYIT-----------VASRNTGLSNSGTQIKKIVS--------------------PTGPPQTSGQKMLLQVVKTADGNTLYRNPNGQLMQLVPLSQIKALKPNLLSQGQPTIIRLPAPPTVSMNKPQGG-----------------SATIVTSSIPTTQTLAKPSGTVPVSTSSSMGGKLISPPSSKSVSLSSLPSTLKVVQGFLGQSGTCTLRILPPTTSTS---------STVLSQSGLT----LLKSASSMPPTQDSSNSETNVSFSSQSTEK-----TVVQVLKQSTIDPAKQNSSDNANVKEKHFNKAPDPEEKE-IGSDSTELTDDSDLYSDDDQEDASCMSASDREEKIEDTD----------------------GMDSEKKGYAEMVVDIETIEESAEQNRIAKFRASALRRNQYRRNQKRIHDEMLEVRVQKVRKERKRRQTLSECFIKLQGTLGMSSKKFEVSRMRILTKANKEVEYLVKLEDYLVEKKAKLQFKKERYIQTLSQLCDKSTESIGLKLNEIISKQKALEAQSKTKETHPKPIQAKSKAKPKPKSKPKSKVVDVCDKPKGLAVQNKVNDVSKVTYSPSKPIDLSIKKQKSPEMTESVPKSTPSVSVPADLDGNKNTLN--VLDTNTVTTTSTPIQPSFNSTLVMKPVSIPSPIKHPPITRERMRPNILSRASSQAMQGSPVKESLLTNVCIPQVLPLMNTMVPCNQIITINNSLQPIGITSVGQQSSTPGVASVSIVPTISHPLRVENTLPMLHPQFIKITNSPVNINTKVDSASLPNISNVISLAENLVVPRKVVEDKPVFQAQPTSVDNQQNSSNDKIPDLEQKTDEAPSTNVPKQSVVEDQKGASVPKSNPEVPENKSPDDSDDPEDENLLSLLDELVLLSQQLTNEDEDERIAVPGDVQSCSDKPEDQEPADDRALSPLFLTLDEDLMSPDSKDEIDIPPKVDDLVKVIFGSDSPSVSSESGVAQSTNASSPHASTCNATGDGLTPPPLLHMKAAYEAAS-------------------GQSANEGTSVTWRPMPKLVPLGLKAQDAGKVIN------------------PSIPNLDSSEQDTPQM--", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *** :: :::* *.. ** ::**:*** ...:.:. * .* . . * :.. .:. . ****. ********.*****:. .*****************: ::*::. :*:*.***.*.*. ****.*: ***.******: *:*:*****::* :**: *****:*** * ******************::*::**:*. ::: *: *.* *::*.************: ****************:*.:. :..: : .:.: *.: *. :. * . :.:: . : : . : .. :: :. :. :. .: : . .: ..:: : *:*: .: ... : . . ** . . * .: *.*:: : ** .. *. *:. : : *::.: :* : * * .* .:: :. *::: . . :* * :.*: .. *. * . . ** :.:*. : . :. : .. * : .* . :.: ..: :. ::. .. * ::* :* : : . . : .*** .. . *.. .*.. * .. : * .. .: . . :.. .*:. * .. * . ... .* .:..::.*.. .: . . : : .:: . ::... . :.. * :: : .:.*** *: * :.:... *:***. * : . . :..: :: ..:*: *..* . ::: * :::: *:: :.:: * :::. :: . * * *. . . . .: . :::.*..: *. .. *: * *: .: . :. .. . :. . : *:::: :*: . : : : . ...: *: :*: . * :: .:. . * : : : **.:::: . * * . *.:: *. . *: :. :*. .**..: : . * *.:. . : * : . ..: :* : .: . :.: . : :.* :..:..:: * . ..*: . :*. ..* :*: :.*:. : :: *:: ::* ..::: ... .*. : :. . .*: :.. . * * . * : *:. **: :. .. * ::: . . . . : *: :: . : ::*.. .*. *: : .* . : : *:. :: .* * *.: . .: :.:*: . * * .. . :.*. .. . :: ...*.*:. * * . .: .* : *:*: . . . . :: :. . * .: : . :. :. :*. * **: :: . *. :: . :: : . : ..: .:: : : . :.: .. .: :. . .: . * : *: . : : :. . : * :: ..: .:: ...:.::.: . : *: . ** * : . .:: * : * .. *.:..: :: . *.: .* : **.* ::::.* .. ..: . : *:.* * *.:* ::. : *. :..::.: : * . * ..* . .:** :: :.. : . ::* : .** : .: .. . .: .:. :.. : : .:*:* * :. :. * . :*.: : . : .. . : * : : : . : . :: *.:: :* * ::.. * . : . .*: . * :. . . : * ::. : . ..* * :*.:** ::*: . . ... : : :. : . : :* . :.* :: ....: : . . : :*.: . . .: : *: *. :.*:.. :. .: : :** : :. *.: *:::*:.* . . *: : : : :: : : * :. :**:** : : * **: ***: . :**: **.:* .*:: *.. * *: :* * *:. *:.:*.*..*: * : **: * :**:*****.:.*: .. : ..: : :* .. . :. .**: ** :::::.* :.. .. .*..: :*: **: ::. .*:.:. :: .::. :. ..:: .. . :.* ..: :. . * *. ..: * * : . : . :.. * .: : * . :: : : ..: : : * .. :. . . . ..: * ..: : ... :: : .* . :.: . .:* : :: .*: . *::: .:. * :: :: . . :. :. . .::*: ... :: * . .: *: * ::. :***:* *::* :* :.*: : ..: * * ** . . *: *. :.: .. :* * :.::.** ****:. * :. .:...:. . : : ** *.*:. *. . *: :* * :.:*..* ... ", "identical_positions": 443, "similar_positions": 1083, "identity": "13.9%" }, { "cls_id": "homologset.agr.MGI:1352490", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q4V8Q1-1", "uniprot_id": "CAN11_RAT", "id": "Q4V8Q1-1", "name": "Calpain 11", "aln": "MLN-------------------------------------------------------FSDISYAERGMVATIN----------------------------------------------------------------------------------------------------------------------------------------------------SNRLKDKGVGQYQNAYNYKNQ-NFEDLRASCLKMGELFEDPFFPAEPQSIGFKELGPKSQEVHNVYWQRPKDIIHNPQFITNDFSPTDICQGILGDCWLLAAIGSLTTSPKLLFRVVPRSQSFKKNYAGIFHFQLWQFGHWLNVVVDDRLPTKNNKLVFVHASHRQEFWGALLEKAYAKLNGSYEALTGGSTMEGLEDFTGGMAQCIRLQNPPHNLLRLLRKALEKSSLMGCSIEVTNSDDVEKMAHNMLVKGHAYAIT--GLQDVYYRDKLE--TLIRIQNPWG-RIEWNGAWSDKAKEWEEVMPEVQMQLLHKKE-DGEFWMSYEDFMSNFTLLEICNLTPDALSSWDYKS---CWHTTFFEGSWRRGSTAGGCRNYPETFWSNPQFRISLPETDDPEDSSDKSEMVCTCLVALMQKNWRHARE-GPQLLTIGFVVFSVWYVQFQNLQDIHLKKDFFMKYRDHGFSEIFTNTREVNSHLRLPPGEYVIIPSTFEPHKDADFLLRVFTEKHSETWLLDEVNMLEQLQEETIT----------DADLDQNSVELFETLANRDSQVDMYDLQKLLNKMSSKVKSFK----------------------------------------------------------------------------SKGFSLDVCRRMVNLMDKDDSGKLGLHEFHILWKKIKKWMEIFKECDQDRSGNLNSYEMRLAIEKAGIRMNNRVTEVVVARYADANMIVDFDNFINCFLRLKAMFAFFLSMDTKKTGSICLNINQWLHITMWG", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q6J756-1", "uniprot_id": "CAN11_MOUSE", "id": "Q6J756-1", "name": "Calpain-11", "aln": "MLN-------------------------------------------------------YSDISWAEKGMVATIN----------------------------------------------------------------------------------------------------------------------------------------------------HSRLKDKGVGQHQNAYNYKNQ-NYEDLRAECLRKGELFEDPFFPAEPRSIGVKNLGPNSEHMQNIYWQRPKDIIHNPQFITNDFSPTDICQGILGDCWLLAAIGSLTTCPKLLYRVVPRNQSFKKNYAGIFHFQLWQFGHWLNVVVDDRLPTRNNKLVFVHASHRQDFWSALLEKAYAKLIGSYGALSGGSTLEGLEDFTGGVAQCIPLQKPPGNMLRLLKKALEKSSLMGCSIEVTDNSEVETMTHNMLVRGHAYAVT--GLEDVYYRDKLE--TLIRIQNPWG-RVEWNGAWSDKATEWEEVSPDVRVQLLHKKD-DGDFWMSYEDFMSNFTLLEICNLTPDALNTWDYKS---RWHSTFYEGSWRRGSTAGGCRNHPETFWSNPQFKISLPEVDDPEDDSEKNEMVCTCLVALMQKNWRHARE-GPQLLTIGFVIFSVP-KEFQNLRDIHLKKDFFLKYRDHGFSEIFINSREVNSHLRLPPGEYVIIPSTYEPHKDADFLLRVFTEKHSETWLLDDANRFEHLQEETVT----------DKDLDKDSLQLFKIMANEDGEVDMYALHKLLNRMTAKLRNFK----------------------------------------------------------------------------TKGFSLEVCRRMINLLDKDGSGKLELHEFQVLWKKIKKWTEIFKECDEDRSGNLNSYEMRLAIEKAGIKMNNRVTEVVVARYSDN-MIVDFDSFLNCFLRLKAMFAFFLSMDTKKTGSICLDINQWLQITMWG", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9UMQ6-1", "uniprot_id": "CAN11_HUMAN", "id": "Q9UMQ6-1", "name": "Calpain-11", "aln": "MLYSPGPSLPESAESLDGSQEDKP-------------------------------RGSCAEPTFTDTGMVAHIN----------------------------------------------------------------------------------------------------------------------------------------------------NSRLKAKGVGQHDNAQNFGNQ-SFEELRAACLRKGELFEDPLFPAEPSSLGFKDLGPNSKNVQNISWQRPKDIINNPLFIMDGISPTDICQGILGDCWLLAAIGSLTTCPKLLYRVVPRGQSFKKNYAGIFHFQIWQFGQWVNVVVDDRLPTKNDKLVFVHSTERSEFWSALLEKAYAKLSGSYEALSGGSTMEGLEDFTGGVAQSFQLQRPPQNLLRLLRKAVERSSLMGCSIEVTSDSELESMTDKMLVRGHAYSVT--GLQDVHYRGKME--TLIRVRNPWG-RIEWNGAWSDSAREWEEVASDIQMQLLHKTE-DGEFWMSYQDFLNNFTLLEICNLTPDTLS-GDYKS---YWHTTFYEGSWRRGSSAGGCRNHPGTFWTNPQFKISLPEGDDPEDDAEGNVVVCTCLVALMQKNWRHARQQGAQLQTIGFVLYAVP-KEFQNIQDVHLKKEFFTKYQDHGFSEIFTNSREVSSQLRLPPGEYIIIPSTFEPHRDADFLLRVFTEKHSESWELDEVNYAEQLQEEKVS----------EDDMDQDFLHLFKIVAGEGKEIGVYELQRLLNRMAIKFKSFK----------------------------------------------------------------------------TKGFGLDACRCMINLMDKDGSGKLGLLEFKILWKKLKKWMDIFRECDQDHSGTLNSYEMRLVIEKAGIKLNNKVMQVLVARYADDDLIIDFDSFISCFLRLKTMFTFFLTMDPKNTGHICLSLEQWLQMTMWG", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AB32U468-1", "uniprot_id": "A0AB32U468_DANRE", "id": "A0AB32U468-1", "name": "Calpain-1 catalytic subunit", "aln": "--------------------------------------------------------------MFSYGGISAHIS----------------------------------------------------------------------------------------------------------------------------------------------------ANRLKADGAGSFEQALHFQNQ-DYEALRQECLEGGYLFEDPCFPAEPPSLGFKELAPHSSKTRDVEWMRPTELCDDPQFIVGGATRTDICQGALGDCWLLAAIGSLTLNERLLHRVVPHGQSFQDDYAGIFHFQFWQFGEWVDVVIDDRLPVKDGELMFVHSAEGNEFWSALVEKAYAKLNGSYEALSGGSTTEGFEDFTGGVSEMYELRKAPRDLYRIISKALDRGSLLGCSIDITSAFDMESVTFKKLVKGHAYSVT--ALKQVEYRGRME--RLIRIRNPWG-QVEWTGAWSDNSPEWDEIDPSEKDDLHLQME-DGEFWMSFGEFLRQFSRLEICNLTPDALS-DDDMS---HWNTIKFHGAWRRGSTAGGCRNHPNTFWINPQYKITLLEED---DDPEDEEVACSFLVALMQKDRRRYRRHGQDMHTIGFAIYEVRSQWYTGCQNVHLKKDFFLSNSSAARSETFINLREVSTRLRLPPGEYIIVPSTFEPSKEADFVLRVFTEKQSETEELDDEISADLEDEEEIT----------EDDIDDSFKSLFAQLAGEDMEISVHELKTILNRVVSKHKDVK----------------------------------------------------------------------------TDGFSMDSCRTMVNLLDKDGSARLGLVEFQILWNKIRKLLGIFREFDIDKSGTMSSYEMRLAVESAGFKLNNRLNQILVARYAEN-EAIDFDNFVCCLIKLEAMFRSFQQLDREETGTAEMNLSEWLFMTMCG", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8M2BLC4-1", "uniprot_id": "A0A8M2BLC4_DANRE", "id": "A0A8M2BLC4-1", "name": "Calpain-1 catalytic subunit", "aln": "--------------------------------------------------------------MFSIGGVSTRIY----------------------------------------------------------------------------------------------------------------------------------------------------KERLQAEGMGANDLAIKFLNQ-DYEELRRECVESGRLFEDPCFPAVPQSLGFKELAPNSSKTRGVKWIRPTELSENPQFIVGGATRTDICQGALGDCWLLAAIASLTLNDKLLHRVVPHGQSFTNEYAGIFHFQFWQFGEWVDIVIDDRLPVKDKELMFVHSAEGNEFWSALLEKAYAKLNGSYEALSGGSTTEGFEDFTGGVAEMYELRSAPKDLHRIIAKALERGSLLGCSIDITSAFDMEAVTFKKLVKGHAYSVT--ALREVNFRGNRE--RLIRIRNPWG-QVEWTGAWSDNSSEWNGIDPSEREELNNHME-DGEFWMSFQEFKRQFSRLEICNLTPDALS-DDSQH---FWNTIQFNGTWRKGSTAGGCRNNPNTFWINPQYKITLLEED---DDPEDNEVACTFMVALMQKDRRRFRKQGQDMHTIGFALYEVP-DEFLGSQNVHLKKDFFLRHSSCARSETFINLREVSTRLRLPPGEYLIVPSTFEPGKEADFVLRVFTEKQSETQEMDDEISFNLEDEEAVS----------EENIDASFKKMFAQLSGEDMEISVHELRTILNRVMTKHRDLK----------------------------------------------------------------------------TDGFSLESCRCMINLMDKDGSARLGIVEFQILWNKIRKWLGVFRQFDLDKSGTMSSYEMRLAVESAGFKLNNKLHQILVARYSDG-DVIDFDNFVCCLVKLEAMFKSFKELEKEGSGVAELNISEWLYLTMCG", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q11002-1", "uniprot_id": "CANA_DROME", "id": "Q11002-1", "name": "Calpain-A", "aln": "MDDLRGFLRQAGQEFLNAAGEAAMGAAKDVVG-------------------------SVINEIFIKKEADTKR-------------------------------------------------------------------------------------------------------------------------------------------------VLPSIKNMRVLGEKSSSLGPYSEVQ-DYETILNSCLASGSLFEDPLFPASNESLQFSRR-PD----RHIEWLRPHEIAENPQFFVEGYSRFDVQQGELGDCWLLAATANLTQESNLFFRVIPAEQSFEENYAGIFHFRFWQYGKWVDVIIDDRLPTYNGELMYMHSTEKNEFWSALLEKAYAKLHGSYEALKGGSTCEAMEDFTGGVSEWYDLKEAPGNLFTILQKAAERNSMMGCSIEPDPN-VTEAETPQGLIRGHAYSITKVCLIDIVTPNRQGKIPMIRMRNPWGNEAEWNGPWSDSSPEWRYIPEEQKAEIGLTFDRDGEFWMSFQDFLNHFDRVEICNLSPDSLTEDQQNSGKRKWEMSMYEGEWTPGVTAGGCRNFLDTFWHNPQYIITLVDPD-----EEDEEGQCTVIVALMQKNRRSKRNMGMECLTIGFAIYSLN---DRELENRPQGLNFFRYKSSVGRSPHFINTREVCARFKLPPGHYLIVPSTFDPNEEGEFIIRVFSETQNNMEENDDHVGYGGKADTITPGFPTPKP---IDPQKEGLRRLFDSIAGKDMEVDWMELKRILDHSMRDDLPKPVVFNRFSNNMAFETQAAGPGDDGAGACGLLSLICGPFLKGTPFEEQLGMNDQSNKRLIGDNPADGGPVTANAIVDETHGFSKDVCRSMVAMLDADKSGKLGFEEFETLLSEIAKWKAIFKVYDVENTGRVSGFQLREALNSAGYHLNNRVLNVLGHRYGSRDGKIAFDDFIMCAVKIKTYIDIFKERDTEKNETATFTLEEWIERTIYS", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VT65-1", "uniprot_id": "CANB_DROME", "id": "Q9VT65-1", "name": "Calpain-B", "aln": "MYGIDNYPKNYHASGIGLVNLAALGYSKNEVSGGNEGGGAPKPKAGLYPSLPYPSSESVGGMPYVVKQTSHAQNASYAGPTMGMGMPVPEAPSAPAPYPSATPYPGSGLYPSLPSANVSSLPYPTAPMAPYPTGMPYPTGMPQPNLPYPAAPLAPYPSAMPGLPGMPMPYAPMPTSPAPQHNIGFPALPYPTAPPPESAPTQEEEPSVGVAELSFTSVKVPENQNMFWMGRKATSARQNSVSKGDFQSLRDSCLANGTMFEDPDFPATNASLMYSRR-PD----RYYEWLRPGDIADDPQFFVEGYSRFDVQQGELGDCWLLAAAANLTQDSTLFFRVIPPDQDFQENYAGIFHFKFWQYGKWVEVVIDDRLPTYNGELIYMHSTEKNEFWSALLEKAYAKLHGSYEALKGGTTCEAMEDFTGGVTEWYDIKEAPPNLFSIMMKAAERGSMMGCSLEPDPH-VLEAETPQGLIRGHAYSITKVCLMDISTPNRQGKLPMIRMRNPWGNDAEWSGPWSDSSPEWRFIPEHTKEEIGLNFDRDGEFWMSFQDFLNHFDRVEICNLSPDSLTEDQQHSSRRKWEMSMFEGEWTSGVTAGGCRNFLETFWHNPQYIISLEDPD-----DEDDDGKCTAIVALMQKNRRSKRNVGIDCLTIGFAIYHLT---DRDMQVKPQGLNFFKYRASVARSPHFINTREVCARFKLPPGHYLIVPSTFDPNEEGEFIIRVFSETRNNMEENDDEVGFGETDDRIAPSLPPPTPKEEDDPQRIALRRLFDSVAGSDEEVDWQELKRILDHSMRDVMVG-----------------------------------------------------------------------------SDGFSKDAVRSMVAMLDKDRSGRLGFEEFEALLTDIAKWRAVFKLYDTRRTGSIDGFHLRGALNSAGYHLNNRLLNALAHRYGSREGQIPFDDFLMCAIKVRTFIEMFRERDTDNSDTAFFNLDDWLERTIYS", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : ..: * . : .:: : *: * :**** *** *: . *. : * ** :: .:* *: . : *: ** ********* ..** *:.**:* *.* .:*******::**:*.*:::::*****. : :*:::*::. .:**.**:******* *** **.**:* *.:******::: :: .* :: :: ** ::.*::***:: * : : *::****::* * :: .. :**::**** **.*.***.: ** : : :: : **:****: :* :* :*****:**:*. : *. :.* * * :****** *** ***: *:* : * : . *: :******: * *. * : ****.:: : . :** . . * * * *** ::::****.*:*:***::* .:.:*::***:*.:.: *: : . :* ::. . ::. *: :*:: . :.**. : * *: ::* * *.:* : **. * ..: * :*: * .:* :..:.:* .::.** ::**:: : : **.. : **.*: * :::.: : * : . . : :.:*: *: .", "identical_positions": 215, "similar_positions": 219, "identity": "21.16%" }, { "cls_id": "homologset.agr.MGI:1352493", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O95817-1", "uniprot_id": "BAG3_HUMAN", "id": "O95817-1", "name": "BAG family molecular chaperone regulator 3", "aln": "-----MSAATHSPMMQVASGNG--DRDP---LPPGWEIKID----PQTGWPFFVDHNSRTTTWNDPRVPSEGPKETPSSANGPSREGSRLPPAREGHPVYPQLRPGYIPIPVLHEGAENR---------QVHPFHVYP------------QPGMQR-FRTEAAAAAPQRSQSPLRG-MPETTQPDKQCGQV---AAAAAAQPPASHGPERSQSPAASDCSSSSSSASLPSSGRSSLGSHQLPRGYIS-IPVIHEQNVTRPAAQPSFHQAQKTHYPAQQGEYQTHQPVYHKIQGDDWEPRPLRAASPFRSSVQGASSREGSPARSSTPLHSPSPIRVHTVVDRPQQPMTHRETAPVSQPENKPESKPGPVGPELPP-GHIPIQVIRKEVDSKPVSQKPPPPSEKVEVKVPPAPVPCPPPSPGPSAVPSSPKSVATEERAAPSTAPAEATPPKPGEAEAPPKHPG----VLKVEAILEKVQGLEQAVDNFEGKKTDKKYLMIEEYLTKELLALDSVDPEGRADVRQARRDGVRKVQTILEKLEQKAIDVPGQVQVYELQPSNLEADQPLQAIMEMGAVAADKGKKNAGNA-----EDPHTETQQPEATAAATSNPSSMTDTPGNPAAP----------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9JLV1-1", "uniprot_id": "BAG3_MOUSE", "id": "Q9JLV1-1", "name": "BAG family molecular chaperone regulator 3", "aln": "-----MSAATQSPMMQMASGNGASDRDP---LPPGWEIKID----PQTGWPFFVDHNSRTTTWNDPRVPPEGPKDTASSANGPSRDGSRLLPIREGHPIYPQLRPGYIPIPVLHEGSENR---------QPHLFHAYS------------QPGVQR-FRTEAAAATPQRSQSPLRGGMTEAAQTDKQCGQMPATATTAAAQPPTAHGPERSQSPAASDCSSSSSSASLPSSGRSSLGSHQLPRGYIP-IPVIHEQNITRPAAQPSFHQAQKTHYPAQQGEYQPQQPVYHKIQGDDWEPRPLRAASPFRSPVRGASSREGSPARSGTPVHCPSPIRVHTVVDRPQ-PMTHREPPPVTQPENKPESKPGPAGPDLPP-GHIPIQVIRREADSKPVSQKSPPPAEKVEVKVSSAPIPCPSPSPAPSAVPSPPKNVAAEQKAAPSPAPAEPAAPKSGEAETPPKHPG----VLKVEAILEKVQGLEQAVDSFEGKKTDKKYLMIEEYLTKELLALDSVDPEGRADVRQARRDGVRKVQTILEKLEQKAIDVPGQVQVYELQPSNLEAEQPLQEIM--GAVVADKDKKGPEN------KDPQTESQQLEAKAATPPNPSNPADSAGNLVAP----------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8M1N1F2-1", "uniprot_id": "A0A8M1N1F2_DANRE", "id": "A0A8M1N1F2-1", "name": "", "aln": "-MAQYSGAKQYQSMKTLSPVETMATNDP---LPPGWEIKID----PQTGWPFFVDHNNRTTTWNDPRHDTKKIFSNGPSMSPETPQDMHKTFINEMR--QPMLRQGYIPIPVCHENPEPRL--------QQYPSFSYI------------HPAVQQNLRTDGRTPSP----TPAAHCRPRSPVQTP--------SEACSSCSPTSHGPEGYQPQGTHQQISG-----LHQQPRSSN--TGLRAGYIP-IPVIHEG-----AGGVLPSQLSQSSHPTREKIYREQVPIQIQQN---------RAASPIQVPLR-----------------AQSPVMAQIMGERPQMQQHIGHTAIPSKIEHPVEEIIRVPTFEVP---IQRVSEVPQQIHHQPVQQQQQP-TQQPQPKAQPSPQ-VSETSNITIQVPPAPEPQETAAPQTPQEVSSPQLQPEE-TLEQDLSHPG----LVKVQQIVERVEKLAQNVKGFDGKKNDKRYLVLEEMLTKELLALDSVDPEGRPDVRQARRDGVRRVQNILDELEMIG----------EMQAGNEAKGE-------------------------------QSMIDQLNTERVKEFS------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A8JNS4-1", "uniprot_id": "A8JNS4_DROME", "id": "A8JNS4-1", "name": "", "aln": "MKPTVMAANQAQSNPATAAGNNVSPGGPGVNIPVNREYVSGGYGSPQQSAQFHTPQNAYGSPRQQQQHFQQHQQVPPNQQQQHFQPTFGFEPNMDMDNMFPRSHLGRMHDPFAGFGDSRKRSSLHGPSGQVHADDDFPSYFDDPDFGFPRFSTMGRRGRMAGGANTHMDHDDDFFNRLPSEFRQYIPDGFGGRRGTGAAPAPGQVPQQQQPQPQPQYTQQQPQTHFQFGVPPQQQPVYAGPTQQQVPQTPSKRLCDAAIQTEDPAGRSEVDCAPPTNLNQHGLRNTVDMGVKSVAEQDQGLRSHSAPPPEQQQQNLQYHQQQQQHQQPGVHSQPFGTQTSPPVQGQQFKTYYAPHQQTHPQQKQQTPPPAPQTPGGTYVRTIPIFVEGRSEPIINAHKEIPNQNAPPSAQAQAQAQAYAQAQPQAHAAPQQHNRPTPLNTQAQP-EQQVPVEGAAGLPPQTPHTLNSINKIQDIQRDVLELMGKVEQFKGTREEKEYAYLDEMLTRNLLKLDTIDTNGKDSIRLARKEAIKCIQASINVLEAKAEENARAASGAAPAPSATAPAVDTGAVAASEAAGQNAEPVTPQPQDATKMQEPIPLPAPPNAAAVEGAAASEATAAEATQSAVQSETTTTTSE", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .* .. :. : .* :* . * . ** . *.. :* :. :: : : . . : * : * : *. . . : * : : . : : * . : : . . .:. . : *. . : :.. :. * : : . . *:. : : .: : *: *. : * * . : . :. : * : : :*: : .:: : : . ..*: .. . * . * : *:: * . * * *. *.*.: :*.* ::* **::** **::*.:*: .:* **::.:: :* :: ** . .. . :: . ", "identical_positions": 49, "similar_positions": 126, "identity": "7.7%" }, { "cls_id": "homologset.agr.MGI:1352494", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9UBY9-1", "uniprot_id": "HSPB7_HUMAN", "id": "Q9UBY9-1", "name": "Heat shock protein beta-7", "aln": "MSHRTSSTFRAERSFHSSSSSSSSSTSSSASRALPAQDPPMEKALSMFSDDFGSFMRPHSEPLAFPARPGGAGNIKTLGDAYEFAVDVRDFSPEDIIVTTSNNHIEVRAEKLAADGTVMNTFAHKCQLPEDVDPTSVTSALREDGSLTIRARRHPHTEHVQQTFRTEIKI", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P35385-1", "uniprot_id": "HSPB7_MOUSE", "id": "P35385-1", "name": "Heat shock protein beta-7", "aln": "MSHRTSSAFRAERSFRSSSSSSSSS-SSSASRALPAQDPPMEKALSMFSDDFGSFMLPHSEPLAFPARPGGQGNIKTLGDAYEFTVDMRDFSPEDIIVTTFNNHIEVRAEKLAADGTVMNTFAHKCQLPEDVDPTSVTSALREDGSLTIRARRHPHTEHVQQTFRTEIKI", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9QUK5-1", "uniprot_id": "HSPB7_RAT", "id": "Q9QUK5-1", "name": "Heat shock protein beta-7", "aln": "-----------------------SSSSSSASRALPAQDPPMEKALSMFSEDFGSFMLPHSEPLTFPARPGGQGNIKTLGDAYEFTVDMRDFSPEDIIVTTSNNHIEVRAEKKP---------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ** ***********************:****** ******:******* ************:**:************ ********** . ", "identical_positions": 80, "similar_positions": 5, "identity": "47.06%" }, { "cls_id": "homologset.agr.MGI:1352495", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A0G2KB91-1", "uniprot_id": "A0A0G2KB91_RAT", "id": "A0A0G2KB91-1", "name": "", "aln": "-------------MILG----------------------SLSRAGPLP-LLRQPPIMQPPMDLKQILPFPLEPAP-TLGLFSNYSTMDPVQKAVLSHTFGGPLLKTKRPVISCNVCQIRFNSQSQAEAHYKGNRHARRVKGIEAAKTRGREPSVRESG---DPAPAGSTP------------------PSGDGVAPRPVSMENG------------LGPAPGSPEKQPGSPSPPSVPESGQGVTKGEGGTSVPASLPGGSKEEEEKAKRLLYCALCKVAVNSLSQLEAHNKGTKHKTILEARSGLGPIKAYPRLGPPTPGE-----PEAPAQDRTFHCEICNVKVNSEVQLKQHISSRRHRDGVAGKPNPLLSRHKKPRGAAELAGTLTFSKELPKSLAGGLLPSPLAVAAVMAAAAGS-PLSLRPAPAAP-----LLQGPPITHPLLHPAPGPIRTAHGPILFSPY", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8VD12-1", "uniprot_id": "Z385A_MOUSE", "id": "Q8VD12-1", "name": "Zinc finger protein 385A", "aln": "-------------MILG----------------------SLSRAGPLP-LLRQPPIMQPPMDLKQILPFPLEPAP-TLGLFSNYSTMDPVQKAVLSHTFGGPLLKTKRPVISCNVCQIRFNSQSQAEAHYKGNRHARRVKGIEAAKTRGREPSVRESG---DPAPAGSIP------------------PSGDGVAPRPVSMENG------------LGPAPGSPEKQPGSPSPPSVPESGQGVTKGEGGTSVPASLPGGSKEEEEKAKRLLYCALCKVAVNSLSQLEAHNKGTKHKTILEARSGLGPIKAYPRLGPPTPGE-----PEAPAQDRTFHCEICNVKVNSEVQLKQHISSRRHRDGVAGKPNPLLSRHKKPRGAAELAGTLTFSKELPKSLAGGLLPSPLAVAAVMAAAAGS-PLSLRPAPAAP-----LLQGPPITHPLLHPAPGPIRTAHGPILFSPY", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q96PM9-4", "uniprot_id": "Z385A_HUMAN", "id": "Q96PM9-4", "name": "Zinc finger protein 385A", "aln": "-------------MILG----------------------SLSRAGPLP-LLRQPPIMQPPLDLKQILPFPLEPAP-TLGLFSNYSTMDPVQKAVLSHTFGGPLLKTKRPVISCNICQIRFNSQSQAEAHYKGNRHARRVKGIEAAKTRGREPGVREPG---DPAPPGSTP------------------TNGDGVAPRPVSMENG------------LGPAPGSPEKQPGSPSPPSIPETGQGVTKGEGGTPAPASLPGGSKEEEEKAKRLLYCALCKVAVNSLSQLEAHNKGTKHKTILEARSGLGPIKAYPRLGPPTPGE-----PEAPAQDRTFHCEICNVKVNSEVQLKQHISSRRHRDGVAGKPNPLLSRHKKSRGAGELAGTLTFSKELPKSLAGGLLPSPLAVAAVMAAAAGS-PLSLRPAPAAP-----LLQGPPITHPLLHPAPGPIRTAHGPILFSPY", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AB32TJD5-1", "uniprot_id": "A0AB32TJD5_DANRE", "id": "A0AB32TJD5-1", "name": "", "aln": "MPAKATSGSLWCGKTLGGRKRRREDGYQSEEEGLMWGAGSINRAGAVPTFLRTPTVIQPHLDMKPFLQFPMETPPHSVGLFHNFNAMDPVQKAVINHTFGVPLVKTKRPIISCNVCQIRFNSESQAEAHYKGNRHARRVKGIETSKSRPQENDKTPPGPVSSPSPTGALPTIPDTDPSKTDETRPEPQLNGPAVAPGPMTVSNPPTPESPGPSACPLLPTPTTPQPPPASSSSPSCGSSNP-EQAGTGAPGAPSVTPSNPETEEDKAKKLLYCSLCKVAVNSLSQLEAHNKGTKHKTILEARSGLGPIKAYPRLGPKPSGEQGGGATDPNTQERTFHCEICNVRVNSELQLKQHISSRRHRDGVAGKPNPLLSRHKKHRG-ADLA-------DLTKALGAGLLPSPLAVAAAMAAAASSNPLALRAAAPAPHPHHHLLQAPHLSHAILRPAPGPIRTSHGPILFSPY", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ** *:.***.:* :** *.::** :*:* :* **:*..* ::*** *:.:********:.**** **:*****:****:*******:********************::*:* :* . .* .*:*.*: * .* .*** *:::.* * *:* :*: *.*.*.** .:. * *.. .*: *...: **:***:****:****************************************** ..** .:. :*:**********:****:**************************** ** .:** :*.*:*..***********.*****.* **:**.*..** ***.* ::*.:*:********:*********", "identical_positions": 250, "similar_positions": 90, "identity": "53.53%" }, { "cls_id": "homologset.agr.MGI:1352498", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8VBU2-1", "uniprot_id": "NDRG2_RAT", "id": "Q8VBU2-1", "name": "Protein NDRG2", "aln": "-MAELQEVQITEEKPLLPGQTPEAAKEAELAARILLDQGQTHSVETPYGSVTFTVYGTPKPKRPAIFTYHDVGLNYKSCFQPLFQFGDMQEIIQNFVRVHVDAPGMEEGAPVFPLGYQYPSQDQLADMIPCILQYLNFSTIIGVGVGAGAYILSRYALNHPDTVEGLVLINIDPNAKGWMDWAAHKLTGLTSSIPEMILGHLFSQEELSGNSELIQKYRSLITHAPNLENIELYWNSYNNRRDLNFERGGEMTLKCPVMLVVGDQAPHEDAVVECNSKLDPTQTSFLKMADSGGQPQLTQPGKLTEAFKYFVQGMGYMASSCMTRLSRSRTASLTSAASIDGSRSRSRTLSQSSESGTLPSGPPGHTMEVSC", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9QYG0-1", "uniprot_id": "NDRG2_MOUSE", "id": "Q9QYG0-1", "name": "Protein NDRG2", "aln": "-MAELQEVQITEEKPLLPGQTPETAKEAELAARILLDQGQTHSVETPYGSVTFTVYGTPKPKRPAIFTYHDVGLNYKSCFQPLFRFGDMQEIIQNFVRVHVDAPGMEEGAPVFPLGYQYPSLDQLADMIPCILQYLNFSTIIGVGVGAGAYILSRYALNHPDTVEGLVLINIDPNAKGWMDWAAHKLTGLTSSIPDMILGHLFSQEELSGNSELIQKYRGIIQHAPNLENIELYWNSYNNRRDLNFERGGETTLKCPVMLVVGDQAPHEDAVVECNSKLDPTQTSFLKMADSGGQPQLTQPGKLTEAFKYFLQGMGYMASSCMTRLSRSRTASLTSAASIDGSRSRSRTLSQSSESGTLPSGPPGHTMEVSC", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9UN36-1", "uniprot_id": "NDRG2_HUMAN", "id": "Q9UN36-1", "name": "Protein NDRG2", "aln": "-MAELQEVQITEEKPLLPGQTPEAAKEAELAARILLDQGQTHSVETPYGSVTFTVYGTPKPKRPAILTYHDVGLNYKSCFQPLFQFEDMQEIIQNFVRVHVDAPGMEEGAPVFPLGYQYPSLDQLADMIPCVLQYLNFSTIIGVGVGAGAYILARYALNHPDTVEGLVLINIDPNAKGWMDWAAHKLTGLTSSIPEMILGHLFSQEELSGNSELIQKYRNIITHAPNLDNIELYWNSYNNRRDLNFERGGDITLRCPVMLVVGDQAPHEDAVVECNSKLDPTQTSFLKMADSGGQPQLTQPGKLTEAFKYFLQGMGYMASSCMTRLSRSRTASLTSAASVDGNRSRSRTLSQSSESGTLSSGPPGHTMEVSC", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q5PR98-1", "uniprot_id": "NDRG2_DANRE", "id": "Q5PR98-1", "name": "Protein NDRG2", "aln": "MTTEMQEIAITEEKPLLPGQS-DAVKDAEIAARILLDQGQEHTVETPHGVLHVTVHGSGNARRPAILTIHDVGMDSKSCFSTLFRFEEMQEIVKNFTVVHIDAPGQEEGAAVYPAGYQYASMDQVSEMLPAVLQFFNFRTIIGVGVGAGAYILSRFTLNNPEAVEGLVLVNVDPNARGWMDWAAHKLSNLTSSLSDQIISHLFSQQELSANTELIQTHRERITKAPNLLNIELFWKSYLGRRDLSLDRNN--TFKCPVMLVVGDQAPYEEAAVECNSKLDPTTTSFLKMADAGGMPQLTQPSKLTEAFKYFIQGMGYMASSCMTRLSRSRTTSLSSSYSMEGSRSRSRTLSQGSQGGQLPP-SPSNTMEVSC", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :*:**: ***********: ::.*:**:********** *:****:* : .**:*: :.:****:* ****:: ****..**:* :****::**. **:**** ****.*:* ****.* **:::*:*.:**::** **************:*::**:*::******:*:****:**********:.****:.: *:.*****:***.*:****.:* * :**** ****:*:** .****.::*.. *::************:*:*.********** ********:** ******.*********:*******************:**:*: *::*.*********.*:.* *.. .*.:******", "identical_positions": 251, "similar_positions": 92, "identity": "67.47%" }, { "cls_id": "homologset.agr.MGI:1352499", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q6AYR2-1", "uniprot_id": "NDRG3_RAT", "id": "Q6AYR2-1", "name": "Protein NDRG3", "aln": "-MDELQDVQLTEIKPLLNDKNGTRNFQDFDCQEHDIETPHGMVHVTIRGLPKGNRPVILTYHDIGLNHKSCFNTFFNFEDMQEITQHFAVCHVDAPGQQEAAPSFPTGYQYPTMDELAEMLPPVLTHLSMKSIIGIGVGAGAYILSRFALNHPELVEGLVLINIDPCAKGWIDWAASKLSGLTTNVVDIILAHHFGQEELQANLDLIQTYRLHIAQDINQENLQLFLGSYNGRRDLEIERPILGQNDNRLKTLKCSTLLVVGDNSPAVEAVVECNSRLDPINTTLLKMADCGGLPQVVQPGKLTEAFKYFLQGMGYIP-------------SASMTRLARSRTHSTSSSIGSGESPFSRSVTSNQSDGTQESCESPDVLDRHQTMEVSC", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9QYF9-1", "uniprot_id": "NDRG3_MOUSE", "id": "Q9QYF9-1", "name": "Protein NDRG3", "aln": "-MDELQDVQLTEIKPLLNDKNGTRNFQDFDCQEHDIETPHGMVHVTIRGLPKGNRPVILTYHDIGLNHKSCFNTFFNFEDMQEITQHFAVCHVDAPGQQEAAPSFPTGYQYPTMDELAEMLPPVLTHLSMKSIIGIGVGAGAYILSRFALNHPELVEGLVLINIDPCAKGWIDWAASKLSGFTTNIVDIILAHHFGQEELQANLDLIQTYRLHIAQDINQENLQLFLGSYNGRRDLEIERPILGQNDNRLKTLKCSTLLVVGDNSPAVEAVVECNSRLDPINTTLLKMADCGGLPQVVQPGKLTEAFKYFLQGMGYIP-------------SASMTRLARSRTHSTSSSIGSGESPFSRSVTSNQSDGTQESCESPDVLDRHQTMEVSC", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9UGV2-1", "uniprot_id": "NDRG3_HUMAN", "id": "Q9UGV2-1", "name": "Protein NDRG3", "aln": "-MDELQDVQLTEIKPLLNDKNGTRNFQDFDCQEHDIETTHGVVHVTIRGLPKGNRPVILTYHDIGLNHKSCFNAFFNFEDMQEITQHFAVCHVDAPGQQEGAPSFPTGYQYPTMDELAEMLPPVLTHLSLKSIIGIGVGAGAYILSRFALNHPELVEGLVLINVDPCAKGWIDWAASKLSGLTTNVVDIILAHHFGQEELQANLDLIQTYRMHIAQDINQDNLQLFLNSYNGRRDLEIERPILGQNDNKSKTLKCSTLLVVGDNSPAVEAVVECNSRLNPINTTLLKMADCGGLPQVVQPGKLTEAFKYFLQGMGYIP-------------SASMTRLARSRTHSTSSSLGSGESPFSRSVTSNQSDGTQESCESPDVLDRHQTMEVSC", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9PUP4-1", "uniprot_id": "A0A8M9PUP4_DANRE", "id": "A0A8M9PUP4-1", "name": "", "aln": "-MDELQDVQLTEIKPLLTYKN-SQNFQDFDCQEHDIETPHGVLHVTMRGSPKGNRPVILTYHDIGLNHKSCFNTLFNFEDMMEITQHFAVVHVDAPGQQEGGPPFPTGYLYPTMDELAEMLPSVLTQLKVNSVIGIGVGAGAYILTRFALIHPSLVEGLVLINVDPCAEGWIDWAASKLTGWTSNLVDIVMAHHFSTEELTDNQELIQTYRLHIAQDINQDNLALFCGSYNARQDLGIERPIAGLNENIVKTLTCPALLVVGDTSPAVEAVVECNSRLNPTKTTLLKMADCGGLPQVVQPGKLAEAFKYFVQGMGYIPHVLLSHLSCESVPAAGMTRLSRSRS--SSSSITSTDGSRNRNLN-SPLDG---PNSGP------QTMEVSC", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8M3ANG1-1", "uniprot_id": "A0A8M3ANG1_DANRE", "id": "A0A8M3ANG1-1", "name": "", "aln": "MMDELQDVQLTEIKPLLTDKN-GQNFQDFDCQEHDIETPRGVLHVTLRGTPKGNRPVILTYHDIGLNHKSCFNTLFNFEDMQEITQHFAVVHVDAPGQQESAPPFPTGFLYPTMDELAEMLPSVLTHLKINSVIGIGVGAGAYILTRFALNEPALVEGLVLINVDPCAKGWIDWAASKLSGWTSNLIDIVMAHHFSTDELTENQEIIQTYRLHIAQDINQDNLALFCQSYNSRRDLEIERPVLGMNENAVKTLKCPALLIVGDTSPAVEAVVECNSRLNPTKTTLLKMADCGGLPQVVQPGKLAEAFKYFVQGMGYIPHVLLSHLNSESVPTASMTRLARSRTH-SASSMGSGDGSRSRTQTSSQMEG---ATGGPALDNQNRTMEVSC", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ****************. ** :**************.:*::***:** ***********************::****** ******** *********..*.****: ************.***:*.::*:************:**** .* *********:****:**********:* *:*::**::****. :** * ::*****:********:** ** ***.*:** ****: * *:* ***.*.:**:***.**************:* :*********************:******:******* :*.****:***: ::**: * :.. .*. . . :* . .* :******", "identical_positions": 266, "similar_positions": 66, "identity": "68.38%" }, { "cls_id": "homologset.agr.MGI:1352500", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "B5DEJ6-1", "uniprot_id": "B5DEJ6_RAT", "id": "B5DEJ6-1", "name": "Thiamine pyrophosphokinase", "aln": "--------------------MEHVFTPLEPLLPTGDLKFCLVVLNQTLDP---HFRHLWRKALLRACADGGANHLYDLTEGE---RESFLPEFINGDFDSIRPEVKEYYTKKGCDLISTPDQDHTDFTKCLQVLQRKIEE--------------------------------------KELQVDVIVTLGGLGGRFDQIMASVNTLFQATD-IIPVPIIIIQKESLIYLLQPG-KHRLRVDTGMEG---SWCGLIPVGQPCNHVTTTGLKWNLTNDVLGFGT-LVSTSNTYDGSG------LVTVETDHPLLWTMAIKT--------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9R0M5-1", "uniprot_id": "TPK1_MOUSE", "id": "Q9R0M5-1", "name": "Thiamine pyrophosphokinase 1", "aln": "--------------------MEHAFTPLEPLLPTGNLKYCLVVLNQPLDA---RFRHLWKKALLRACADGGANHLYDLTEGE---RESFLPEFVSGDFDSIRPEVKEYYTKKGCDLISTPDQDHTDFTKCLQVLQRKIEE--------------------------------------KELQVDVIVTLGGLGGRFDQIMASVNTLFQATH-ITPVPIIIIQKDSLIYLLQPG-KHRLHVDTGMEG---SWCGLIPVGQPCNQVTTTGLKWNLTNDVLGFGT-LVSTSNTYDGSG------LVTVETDHPLLWTMAIKS--------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9H3S4-1", "uniprot_id": "TPK1_HUMAN", "id": "Q9H3S4-1", "name": "Thiamine pyrophosphokinase 1", "aln": "--------------------MEHAFTPLEPLLSTGNLKYCLVILNQPLDN---YFRHLWNKALLRACADGGANRLYDITEGE---RESFLPEFINGDFDSIRPEVREYYATKGCELISTPDQDHTDFTKCLKMLQKKIEE--------------------------------------KDLKVDVIVTLGGLAGRFDQIMASVNTLFQATH-ITPFPIIIIQEESLIYLLQPG-KHRLHVDTGMEG---DWCGLIPVGQPCMQVTTTGLKWNLTNDVLAFGT-LVSTSNTYDGSG------VVTVETDHPLLWTMAIKS--------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F1RBJ9-1", "uniprot_id": "F1RBJ9_DANRE", "id": "F1RBJ9-1", "name": "Thiamine pyrophosphokinase", "aln": "---------------------MDEFTPLDCLLPSGKQRICLVILNQPLDER--YFHVLWSKAQIRACADGGANHLYRLTEGR---RESFLPDYINGDFDSILPEVKAFYAGKNCKLMETPDQDLTDFTKCLAIMLEEIKA--------------------------------------KKLQIDSIVTLGGLGGRFDQTMATVETLFHAQK-MTDLPVVVIQDSSLAFLLKEGRHHQLNVNTGMEG---KWCSLVPVGSPC-LTTTSGLKWNLDNQVLAFGQ-LVSTSNTYEDHDPKDCRKPVTITTDNPLLWSMGIKRLQSSQTFL", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P35202-1", "uniprot_id": "THI80_YEAST", "id": "P35202-1", "name": "Thiamine pyrophosphokinase", "aln": "MSEECIENPERIKIGTDLINIRNKMNLKELIHPNEDENSTLLILNQKIDIPRPLFYKIWKLHDLKVCADGAANRLYDYLDDDETLRIKYLPNYIIGDLDSLSEKVYKYYRKNKVTIIKQTTQYSTDFTKCVNLISLHFNSPEFRSLISNKDNLQSNHGIELEKGIHTLYNTMTESLVFSKVTPISLLALGGIGGRFDQTVHSITQLYTLSENASYFKLCYMTPTDLIFLIKKN-GTLIEYDPQFRNTCIGNCGLLPIGEATLVKETRGLKWDVKNWPTSVVTGRVSSSNRFVGDN------CCFIDTKDDIILNVEIFVDKLIDFL-", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . :. : : .. . . *::*** :* * :* ::.****.**:** :. * .:**::: **:**: :* :* : ::. . * ******: :: .:: ..: :::***:.***** : :: *: . . : : .* :*:: . :. :. :.. *.*:*:*.. * ****:: * .. **:** : . . : *.. :: .: * ", "identical_positions": 58, "similar_positions": 88, "identity": "17.74%" }, { "cls_id": "homologset.agr.MGI:1352501", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZAZ5-1", "uniprot_id": "BCAR3_RAT", "id": "D3ZAZ5-1", "name": "Breast cancer anti-estrogen resistance protein 3 homolog", "aln": "--------------------------------------------------------------------------------------MAAGKFASLPRHMPVNHQFPLASSMDLLSSKSPLAEHRTEAYPDVSIHGTLPRKK-KGPP--PIRSCDSASHMGTLPHSKSPRQ---SSPLTQDLILEKPLPDWKGDSFAFRDPYLLDPTLEYVKFSKERHIMDRTPERLKKELEEELLLSSEDLRSHAWYHGRIPRQVSENLVQRDGDFLVRDSLSSPGNFVLTCQWKNLAQHFKINRTVLRLSEAYSRVQYQFEMESFDSIPGLVRCYVGNRRPISQQSGAIIFQPINRTVPLWCLEERYG--------------TSPGRGREGSFAEGRPDVVKRLSLTTGG-IQARDHSLPRGNLLRNKDKSGSQ-----PACLDHVQDRKAATLKAHQSESHLPIGCKLPPQSPSVDTSPCPNSPVFRTGSEPTLSPALVRRFSSDARAGEALRGSDSQLCPKPPPKPCKVPFLKVPPSPS------------------PWLN------SEANYCELNPAFAVGCDRGAKLLSQALDSHEMLLTAKQNGASGPRNSGINYSILDGDDQGRHWDPLAVQTDEGQEDETKFVPPVMETVSSFRPNDFESKLLP-PENKPLETAMLKHAKELFTNHDARVIAQHMLSVDCKVARILEVSEDMKRSMGVSSGLELITLPHGRQLRLDIIERHNTMAIGIAVDILGCTGTLENRAGTLNKIIQVAMELKDTMGDLYSFSAIMKALEMPQITRLEKTWTALRHHYTQTAILYEKQLKPFSKILHEGRESTYVPASSVSVPLLMPLVT-----------LMERQAVTFEGTDMWE--KNDESCEIMLSHLATARFMAEASESYRMNAERVLADFQP--DEEMTEILKTEFQMRLLWGSKGAEVNQNERYDKFNQILTALSRKLEPPSGKQAEL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9QZK2-1", "uniprot_id": "BCAR3_MOUSE", "id": "Q9QZK2-1", "name": "Breast cancer anti-estrogen resistance protein 3 homolog", "aln": "--------------------------------------------------------------------------------------MAAGKFASLPRNMPVNHQFPLASSMDLLSSKSPLAERRTDAYQDVSIHGTLPRKK-KGPP--SIRSCDNAG------HSKSPRQ---SSPLTQDIIQENPLQDRKGENFIFRDPYLLDPTLEYVKFSKERHIMDRTPERLKKELEEELLLSSEDLRSHAWYHGRIPRQVSENLVQRDGDFLVRDSLSSPGNFVLTCQWKNLAQHFKINRTVLRLSEAYSRVQYQFEMESFDSIPGLVRCYVGNRRPISQQSGAIIFQPINRTVPLWCLEERYG--------------TSPGRGREGSLAEGRPDVVKRLSLTTGSSIQAREHSLPRGNLLRNKEKSGSQ-----PACLDHVQDRKALTLKAHQSESHLPIGCKLPPQSPSMDTSPCPSSPVFRTGSEPTLSPALVRRFSSDARTGEALRGSDSQLCPKPPPKPCKVPFLKTPPSPS------------------PWLT------SEANYCELNPAFAVGCDRGAKLPMQAHDSHEMLLTAKQNGPSGPRNSGINYMILDGDDQARHWDPLAVQTDEGQEDKTKFVPPLMETVSSFRPNDFESKLLP-PENKPLETAMLKHAKELFTNHDARVIAQHMLSVDCKVARILEVSEDRKRSMGVSSGLELITLPHGRQLRLDIIERHNTMAIGIAVDILGCTGTLENRAGTLNKIIQVAVELKDAMGDLYAFSAIMKALEMPQITRLEKTWTALRHHYTQTAILYEKQLKPFSKILHEGRESTYVPASNVSVPLLMPLVT-----------LMERQAVTFEGTDMWE--NNDESCEILLNHLATARFMAEASESYRMNAERILADFQP--DEEMTEILRTEFQMRLLWGSKGAEVNQNERYDKFNQILTALSRKLEPPSGKQAEL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O75815-1", "uniprot_id": "BCAR3_HUMAN", "id": "O75815-1", "name": "Breast cancer anti-estrogen resistance protein 3", "aln": "--------------------------------------------------------------------------------------MAAGKFASLPRNMPVNHQFPLASSMDLLSSRSPLAEHRPDAYQDVSIHGTLPRKK-KGPP--PIRSCDDFSHMGTLPHSKSPRQ---NSPVTQDGIQESPWQDRHGETFTFRDPHLLDPTVEYVKFSKERHIMDRTPEKLKKELEEELLLSSEDLRSHAWYHGRIPRQVSENLVQRDGDFLVRDSLSSPGNFVLTCQWKNLAQHFKINRTVLRLSEAYSRVQYQFEMESFDSIPGLVRCYVGNRRPISQQSGAIIFQPINRTVPLRCLEEHYG--------------TSPGQAREGSLTKGRPDVAKRLSLTMGG-VQAREQNLPRGNLLRNKEKSGSQ-----PACLDHMQDRRALSLKAHQSESYLPIGCKLPPQSSGVDTSPCPNSPVFRTGSEPALSPAVVRRVSSDARAGEALRGSDSQLCPKPPPKPCKVPFLKVPSSPS------------------AWLN------SEANYCELNPAFATGCGRGAKLPSCAQGSHTELLTAKQNEAPGPRNSGVNYLILDDDDRERPWEPAAAQMEKGQWDKGEFVTPLLETVSSFRPNEFESKFLP-PENKPLETAMLKRAKELFTNNDPKVIAQHVLSMDCRVARILGVSEEMRRNMGVSSGLELITLPHGHQLRLDIIERHNTMAIGIAVDILGCTGTLEDRAATLSKIIQVAVELKDSMGDLYSFSALMKALEMPQITRLEKTWTALRHQYTQTAILYEKQLKPFSKLLHEGRESTCVPPNNVSVPLLMPLVT-----------LMERQAVTFEGTDMWE--KNDQSCEIMLNHLATARFMAEAADSYRMNAERILAGFQP--DEEMNEICKTEFQMRLLWGSKGAQVNQTERYEKFNQILTALSRKLEPPPVKQAEL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F1R3Z4-1", "uniprot_id": "F1R3Z4_DANRE", "id": "F1R3Z4-1", "name": "", "aln": "--------MKHMSISKWLSQLGLPQYCILFDEEYDGVEVKSAHTDLLHLTEMDLLGLGVQSRLHRIHILSSIQVLRERETKRELRMMAEGRFSSLPRNMHVGRQCPLASSMDLLSSRPELSEMPVSGYQGISIHGTLPRKK-KTTTGSPVKQWEVNGNVGSLAAPYPGRHRLPPSPLIHNIIEEH--QTFCSDRKQSRNSAGMDPTMEYVKFSRDKYILDGPPEKLRRELEEELKLSSEEPRSHAWYHGAIPRQVAENLVQRDGDFLIRDSLSSPGNYVLTCQWKNSPQHFKINKRVVAMNEAYSRVQYLFEKEGFDSIPALVRYYVGNREPVSEVIGAIIFQPINRALPLRCLEEKYG--------------VGSIRVEAGYLER-KSLTSKRLSLNIMN-GHGQDHTLSRGNLLSNKDKCGSQ-----PACLNHVQERRRP-LKTHQSESFLPIGSRPQAQVQHMEHQPCPKSPVFRTGSEPALSPTVPRRMAFDTLPGEAIRGSDSQLCPKPPPKPSKVPTVRVPCIPALKTLVVPPVPPVKPHKHRPSLQQQQSGSPEMSYCELSPCSPADWEK-----MNSLQANGYVERLKTDGSIKLDRSSYHNAIEALDNDSE--EDTEEDADKEQNGKKAFQKPVFETESAFRPANVNFRLLP-KENKPLEMTVLKKAKELLVSQDPKTIAKHILQADCQVARILNVSEEVKGQMGVSSGLELVTLPHGRQLRLDLIERHNTMAIGVAVDILGCTGSLEERAATLNRIILVALELKDSMGDLYAFSSIMKALDMPQITRLDHTWTSLRRKYTQTAIIYEKSLKPFYKGLYEG--GAEIPLSNASVPLLMPLLT-----------LMERPAVTFEGMDVWE--NTDQGCEIMFRHLEGARAVARNADTYTCNAQRILQDFQP--HEDMLEILRTDFQLRLLWGSRGAAVEQTERYDKFKLILTALSRKLEP-AVKHTEL", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VMJ4-1", "uniprot_id": "Q9VMJ4_DROME", "id": "Q9VMJ4-1", "name": "Breast cancer anti-estrogen resistance protein 3 homolog", "aln": "MGNTQARQLENRQVPNRRSSILWNFRYSNTVRRREDLAVMVHNSRMSISEWLDLLELQQYEGNLQEFSTVDDVVDITDKELKQFGVRGAHRQRMVNSLLGVRAKRRQSMNLEAMSSAPRAVPRRKNSCPLVYLGENPQDMAGSGDSGPGVITTKSGKVLKQLTFDETSTIYEELRPRSKCNSPHWAIEDSRMEGYGSSNATTPLATAQPSPSEQQEAIA------LKKALEWELSLDARELRSHAWYHGALPRQRAEEIVQREGDFLVRDCASQPDNYVLSCRSKAAVLHFVLNKLVLQPETVYERVQYQFEEDAFDTVPDLITFYVGSGKPISSASGALIQFPCNRTYPLSFYGHKIVGNQLHTQMLAGLRGLSPLNSPMGSNGAVGAGMNATFRFEPQQQQQQQLSPMAGSPASPHCSPPRARREVPPPPRLPCKKQQRSQSLTPAQAMLVSNINKLQEQQLQMQELENGNGNGIMRFQTIARCNPTSEQHLESKFTTHSLPRPNTSAAHALRQQAVARISSLARNCSLD-----------------SPSDSRP---PSPPPKPRKEPMAAVLAYQASGSDSGNGSGDSALGDACEASVQRGVIIKNPRFMTTSVSNGTLKSFTEFDVLAAEEELFTMAIEEVKTASKFDFENFVTLLLPSVENKPLDGDALNTFKMMLLETGPKLLAEHITRID--IALFLEEPSNEEDYYLSCSGLELLTLPHGKVFREDIIERTQCIKLMVAVTILTCQTDLDR-AQLLSKWIQIAVETKTALGNLFGFCAIMLGLCMQQIQKLDQAWHILRQQYTDSAFTFEAKLRPTLSIMNEASNPQAPNTTVPHVLLYALLIDRPVMDIINHSNIDDRPALYHTCIAPWESKADDFGMTINFQHLDASRGFLKNLELYRKNAKIILEDASPRLDELLADAFRTEFHVKFLWGSSGATAKAEDRHNKLEKVLTLMADKFCMMAEQ----", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . : : : * : : .:: :** . .. : : . . . : . . * : . : :. .* : .::. * *:: ** ** *.:.: ******** :*** :*::***:****:**. *.*.*:**:*: * ** :*: *: . .*.**** ** :.**::* *: ***. .*:*. **:* * **: ** .: .. . * . : : : : :. . : . :: *. * :::: *.. *: *. * : . . ::* : . .*: ::. . . . * . * . .::. : . . . .* .. : .. : : . . : : : .:* * * :. :** *****: *: * :: . ..: :*:*: * :* :* ..: . .*****:*****: :* *:*** : : : :** ** * *: * *.: * :*:* * ::*:*:.*.::* .* * ** :*:::* **::**::*: :* .*:* . : *. . * * *: : :* *: . ** * . * : ** :* . . : * **: :* . .* .* : : :*:*::::**** ** .: :*::*:: :** :: *: . : ", "identical_positions": 174, "similar_positions": 229, "identity": "17.81%" }, { "cls_id": "homologset.agr.MGI:1352502", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "B5DEH0-1", "uniprot_id": "LIMD1_RAT", "id": "B5DEH0-1", "name": "LIM domain-containing protein 1", "aln": "------MDKYDDLGLEASKFIEDLNMYEASKDGLFRVDKGASNN---------PEFEETRRVFATKMAKIHLQQQQQQQLLQEEALPRAGRSPINGGNRQG---------VSSKLAADGAAKPPLAVPTVAPGLATTTMAVQSSYPPQEQRTRPSAHGARPGSQNCGSREGPVSSQRPALHGLGP-CEDPSCLTHGDYYDNFSLASPQWGDKPEESPSMSLSVG--SGWPGCPGNDSLSHRSCGDSHPYHPQLS-MCSGRSFES---GQDSGIGGHSSEKPTGLWSTASSQRVNLGFSSTGLENGT----PAQPKGTTVSAPMVPSSTSQGACLRRDSSLGYEAPGRVFKPLVDTQPWLQDGPKSYLSVSAPLSSTTSKDNAQTGMTAGLDPKLGCVESG---TSPKPSPTSNVHPVMSAPSELSCKESPPSWSTDSSLGP---------VLPESPTPSR----------------VRLPCQTLTPGPELGPSTAELKLEALTQRLEREMD-AHPKADYFGACVKCSKGVFGAGQACQAMGDLYHDACFTCAACSRKLRGKAFYFVNGKVFCEEDFLYSGFQQSADRCFLCGHLIMDMILQALGKSYHPGCFRCVICNECLDGVPFTVDSENKIYCVRDYHKVLAPKCAACGLPILPPEGSDETIRVVSMDRDYHVECYHCEDCGLELNDEDGHRCYPLEDHLFCHSCHVKRLEKGPSPASLHQHHF--------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9QXD8-1", "uniprot_id": "LIMD1_MOUSE", "id": "Q9QXD8-1", "name": "LIM domain-containing protein 1", "aln": "------MDKYDDLGLEASKFIEDLNMYEASKDGLFRVDKGAGNN---------PEFEETRRVFATKMAKIHLQQQQQQQLLQEEALPRAGRSPVNGGNRQG---------ASGKLAADGAAKPPLAVPTVAPGLATTTAAAQPSYPSQEQRIRPSAHGARPGSQNCGSREGPVSSQRPALHGLSPSCEDPSCLTHGDYYDNFSLASPQWGDKPEGCPSVSLGVG--SGWPGCPGNDSTLPKSCGDHHPYQPQLSTVCSGRSFESGISGQDGGIGGHSSEKPTGLWSTASSQRVNLGFSSMGLENGT----SAQPKGTTVSAPMVPSSASQGACPKRDSGLGYEASGRVFKPLVDTQPWLQDGPKSYLSVSAPLSSTAGKDSTQPGMTTGLDPKFGCVESG---TSPKPSPTSNVHPVMSTPSELSCKESSPSWSTDSSLEP---------VLPGSPTPSR----------------VRLPCQTLAPGPELGPSTAELKLEALTQRLEREMD-AHPKADYFGSCVKCSKGVFGAGQACQAMGDLYHDACFTCAACSRKLRGKAFYFVNGKVFCEEDFLYSGFQQSADRCFLCGHLIMDMILQALGKSYHPGCFRCVICNECLDGVPFTVDSENKIYCVRDYHKVLAPKCAACGLPILPPEGSDETIRVVSMDRDYHVECYHCEDCGLELNDEDGHRCYPLEDHLFCHSCHVKRLEKGPSPAPLHQHHF--------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9UGP4-1", "uniprot_id": "LIMD1_HUMAN", "id": "Q9UGP4-1", "name": "LIM domain-containing protein 1", "aln": "------MDKYDDLGLEASKFIEDLNMYEASKDGLFRVDKGAGNN---------PEFEETRRVFATKMAKIHLQQQQQQ-LLQEETLPRGSRGPVNGGGRLGP--QARWEVVGSKLTVDGAAKPPLAASTGAPGAVTTLAAGQPPYPPQEQRSRPYLHGTRHGSQDCGSRESLATSEMSAFHQPGP-CEDPSCLTHGDYYDNLSLASPKWGDKPGVSPSIGLSVG--SGWPSSPGSDPPLPKPCGDHPLNHRQLS-LSSSRSSEGSLGGQNSGIGGRSSEKPTGLWSTASSQRVSPGLPSPNLENGAPAVGPVQPRTPSVSAPLALSCPRQGGLPRSNSGLGGEVSGVMSKPNVDPQPWFQDGPKSYLSSSAPSSSPAGLDGSQQGAVPGLGPKPGCTDLG---TGPKLSPTSLVHPVMSTLPELSCKEGPLGWSSDGSLGS---------VLLDSPSSPR----------------VRLPCQPLVPGPELRPSAAELKLEALTQRLEREMD-AHPKADYFGACVKCSKGVFGAGQACQAMGNLYHDTCFTCAACSRKLRGKAFYFVNGKVFCEEDFLYSGFQQSADRCFLCGHLIMDMILQALGKSYHPGCFRCVICNECLDGVPFTVDSENKIYCVRDYHKVLAPKCAACGLPILPPEGSDETIRVVSMDRDYHVECYHCEDCGLELNDEDGHRCYPLEDHLFCHSCHVKRLEKRPSSTALHQHHF--------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9PS61-1", "uniprot_id": "A0A8M9PS61_DANRE", "id": "A0A8M9PS61-1", "name": "", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MD-THTLS--LGWCVKCSGGVYSSDQACQAMGRVYHDRCFTCCTCGQKLKGKPFYDFSGQVFCEEDYLYSSVKHFAEVCSSCGYLITDMVLQALGKSFHRECFRCVVCNETLEGQQFSVDAQNKIYCVKDYHRFLAQTCAVCEQLILPIEGSNESMRVLTMGRSYHVACYEGKSNI--------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VY77-1", "uniprot_id": "AJUBA_DROME", "id": "Q9VY77-1", "name": "LIM domain-containing protein jub", "aln": "MTTQRTQTQARNPGNSDSDYETLMQRLHIGGGGGAGVGGGGGSGGPGDGGVAMRSYQRSPGAIENYLQESQQQQQQHQMQQMQQLHHNQDYKLYERGNIIAASKYATPRPVEQIQHTHNGSAQIYAPTAQILGQRIAPQKHSPVYENLEFYGQFDSNHKRAQPQSPGSRQSAILNGYLLMQPIRAGRFAHTPVPENQGSASLGTTRAAGGPPPPSGRSAALGPTGDLEEHAAPIYENIIPHSG---QRAQPQASPATATMYQEMQPTSNSSGSSSTAGLDLNALLASPMHQRSISSNTASSSSLGS----PTQRYRNLSLPSHLSPVPTAQSVAKLQQHTPVKSPGGAINVSVNPNYIEDINSSDYVCMTANLHRNTAAGLATGRAAATGAPAQRTVQEPPIITSSLAMGMATAAPPTTSNAPTSAAAAPAAPTSTASLRATPIAMTAPLAVATSPTPSQGSTAVNAALKPRRGLTKNLLPYSVTPPRPAGPTEAQRKIEELTRQLEEEIEQSEEHGEYFGICHTCGEKVKGAGQACQAMGNLYHTNCFICCSCGRALRGKAFYNVHGRVYCEEDYMYSGFQQTAEKCAICGHLIMEMILQAMGKSYHPGCFRCCVCNECLDGVPFTVDVDHKIYCVNDYHRMFAPKCASCGKGITPVEGTDETVRVVSMDKDFHVDCYICEECGMQLTDEPDKRCYPLDGRLLCRGCHLQRLALQSSPHARHQEPVCASYQYMG", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :: :. . :* * .*. * .:.******* :** ** *.:*.: *:**.** . *:*:****::**..:: *: * **:** :*:***:***:* **** :*** *:* *:** ::*****.***:.:* .** * * * **::*::**::*.:.:** ** :. ", "identical_positions": 80, "similar_positions": 55, "identity": "10.88%" }, { "cls_id": "homologset.agr.MGI:1352504", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "F1LML7-1", "uniprot_id": "F1LML7_RAT", "id": "F1LML7-1", "name": "Huntingtin-interacting protein 1-related protein", "aln": "MNSIKNVPARVLSRRPGHSLEAEREQFDKTQAISISKAINSQEAPVKEKHARRIILGTHHEKGAFTFWSYAIGLPLPSSSILSWKFCHVLHKVLRDGHPNVLHDCQRYRSNIREIGDLWGHLRDQYG--HLVNIYTKLLLTKISFHLKHPQFPAGLEVTDEVLEKAAGTDVNNIFQLTVEMFDYMDCELKLSESVFRQLNTAIAVSQMSSGQCRLAPLIQVIQDCSHLYHYTVKLMFKLHSCLPADT----LQGHRDRFHEQFHSLRNFFRRASDMLYFKRLIQIPRLPEGPPNFLRASALAEHIKPVVVIPEEA----PEEEEPENLIEISSGPPAGEPVQVVADLFDQTFGPPNGSMKDDRDLQIENLKREVETLRAELEKIKMEAQRYISQLKGQVNSLEAELEEQRKQKQKALVDNEQLRHELAQLKALQLEGARNQGLREEAERKASATEARYSKLKEKHNELINTHAELLRKNADTAKQLTVTQQSQEEVARVKEQLAFQMEQVKRESEMKMEEQSDQLEKLKRELVAKAGELAHAQEALSRTEQSGSELSSRLDTLNAEKEALSGAIRQREAELLAAQSLVREKEEALSQEQQRSAQEKGELQGRLAEKESQEQGLQQKLLDEQFAVLRGAAAEAEAILQDAVSKLDDPLHLR-CTSSPDYLVSRAQAALDSVSGLEKGHTQYLAS---SEDASALVAALTRFSHLAADTIVN-GGATSHLAPTDPADRLIDTCRECGARALELMGQLQDQTKLPRAQPSLMRAPLQGILQLGQDLKPKSLDVRQEELGAMVDKEMAATSAAIEDAVRRIEDMMNQARHESSGVKLEVNERILNSCTDLMKAIRLLVMTSTSLQKEIVESGRGAATQQEFYAKNSRWTEGLISASKAVGWGATQLVESADKVVLHMG----KYEELIVCSHEIAASTAQLVAASKVKANKNSPHLSRLQECSRTVNERAANVVASTKSGQEQIEDRGELSDTMDFSGLSLIKLKKQEMETQVRVLELEKTLEAERVRLGELRKQHYVLAGG-MGTPGEEEPSRPSPAPRSGATKKPPLAQKPSIAPRPDNQLDKKDGVYPAQLVNY", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9JKY5-1", "uniprot_id": "HIP1R_MOUSE", "id": "Q9JKY5-1", "name": "Huntingtin-interacting protein 1-related protein", "aln": "MNSIKNVPARVLSRRPGHSLEAEREQFDKTQAISISKAINSQEAPVKEKHARRIILGTHHEKGAFTFWSYAIGLPLSSSSILSWKFCHVLHKVLRDGHPNVLHDYQRYRSNIREIGDLWGHLRDQYG--HLVNIYTKLLLTKISFHLKHPQFPAGLEVTDEVLEKAAGTDVNNIFQLTVEMFDYMDCELKLSESVFRQLNTAIAVSQMSSGQCRLAPLIQVIQDCSHLYHYTVKLMFKLHSCLPADT----LQGHRDRFHEQFHSLKNFFRRASDMLYFKRLIQIPRLPEGPPNFLRASALAEHIKPVVVIPEEA----PEEEEPENLIEISSAPPAGEPV-VVADLFDQTFGPPNGSMKDDRDLQIENLKREVETLRAELEKIKMEAQRYISQLKGQVNGLEAELEEQRKQKQKALVDNEQLRHELAQLKALQLEGARNQGLREEAERKASATEARYSKLKEKHSELINTHAELLRKNADTAKQLTVTQQSQEEVARVKEQLAFQMEQAKRESEMKMEEQSDQLEKLKRELAARAGELARAQEALSRTEQSGSELSSRLDTLNAEKEALSGVVRQREAELLAAQSLVREKEEALSQEQQRSSQEKGELRGQLAEKESQEQGLRQKLLDEQLAVLRSAAAEAEAILQDAVSKLDDPLHLR-CTSSPDYLVSRAQAALDSVSGLEQGHTQYLAS---SEDASALVAALTRFSHLAADTIVN-GAATSHLAPTDPADRLMDTCRECGARALELVGQLQDQTVLPRAQPSLMRAPLQGILQLGQDLKPKSLDVRQEELGAMVDKEMAATSAAIEDAVRRIEDMMSQARHESSGVKLEVNERILNSCTDLMKAIRLLVMTSTSLQKEIVESGRGAATQQEFYAKNSRWTEGLISASKAVGWGATQLVESADKVVLHMG----KYEELIVCSHEIAASTAQLVAASKVKANKNSPHLSRLQECSRTVNERAANVVASTKSGQEQIEDR----DTMDFSGLSLIKLKKQEMETQVRVLELEKTLEAERVRLGELRKQHYVLAGG-MGTPSEEEPSRPSPAPRSGATKKPPLAQKPSIAPRTDNQLDKKDGVYPAQLVNY", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O75146-1", "uniprot_id": "HIP1R_HUMAN", "id": "O75146-1", "name": "Huntingtin-interacting protein 1-related protein", "aln": "MNSIKNVPARVLSRRPGHSLEAEREQFDKTQAISISKAINTQEAPVKEKHARRIILGTHHEKGAFTFWSYAIGLPLPSSSILSWKFCHVLHKVLRDGHPNVLHDCQRYRSNIREIGDLWGHLHDRYG--QLVNVYTKLLLTKISFHLKHPQFPAGLEVTDEVLEKAAGTDVNNIFQLTVEMFDYMDCELKLSESVFRQLNTAIAVSQMSSGQCRLAPLIQVIQDCSHLYHYTVKLLFKLHSCLPADT----LQGHRDRFHEQFHSLRNFFRRASDMLYFKRLIQIPRLPEGPPNFLRASALAEHIKPVVVIPEEA----PEDEEPENLIEISTGPPAGEPV-VVADLFDQTFGPPNGSVKDDRDLQIESLKREVEMLRSELEKIKLEAQRYIAQLKSQVNALEGELEEQRKQKQKALVDNEQLRHELAQLRAAQLEGERSQGLREEAERKASATEARYNKLKEKHSELVHVHAELLRKNADTAKQLTVTQQSQEEVARVKEQLAFQVEQVKRESELKLEEKSDQLEKLKRELEAKAGELARAQEALSHTEQSKSELSSRLDTLSAEKDALSGAVRQREADLLAAQSLVRETEAALSREQQRSSQEQGELQGRLAERESQEQGLRQRLLDEQFAVLRGAAAEAAGILQDAVSKLDDPLHLR-CTSSPDYLVSRAQEALDAVSTLEEGHAQYLTS---LADASALVAALTRFSHLAADTIIN-GGATSHLAPTDPADRLIDTCRECGARALELMGQLQDQQALRHMQASLVRTPLQGILQLGQELKPKSLDVRQEELGAVVDKEMAATSAAIEDAVRRIEDMMNQARHASSGVKLEVNERILNSCTDLMKAIRLLVTTSTSLQKEIVESGRGAATQQEFYAKNSRWTEGLISASKAVGWGATQLVEAADKVVLHTG----KYEELIVCSHEIAASTAQLVAASKVKANKHSPHLSRLQECSRTVNERAANVVASTKSGQEQIEDR----DTMDFSGLSLIKLKKQEMETQVRVLELEKTLEAERMRLGELRKQHYVLAGA-SGSPGEEVAIRPSTAPRSVTTKKPPLAQKPSVAPRQDHQLDKKDGIYPAQLVNY", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A0R4IKR8-1", "uniprot_id": "A0A0R4IKR8_DANRE", "id": "A0A0R4IKR8-1", "name": "Huntingtin-interacting protein 1-related protein", "aln": "MNSIRQVPSRVKSRRTESVLGAEREHFEKQQLSSISKAINSTETPLKEKHARRIILGTHREKGAYTFWSYAVGLPLPSSAILSWKFCHVLHKILRDGHRNTLQDCMRHYSDIAETGLLWTNTRDRHGYALLVSLHAKLLCTKIEFHTKHSEIPASLEVTDELLERTAGTDINNVFQLTVEVFDYMDAELRLAEAVLHQLNMSIAISTLTSGQCKLAPLIQVIQDCSHLYHYTVKLLFKLHACLPADT----LQGHRERFHDQFHSLKTFLNKARDMLYFKRLIQIPRLPDSPPNFLRASALAEHVKPMVVIPDEEELEEQEEDEPEPLIDVSEALPVAASQPLQSDIFDQAFGPPKDGF-DDRDLQIERLKREIELLQAELEKIKGEAQRYITQLKAQINSLEGELEEQRMQKQRTLVENEQLRMELEATHRRNTEHESMQTNFVETEKRAQATELRYNKLKEKHAELVANHAELLRKSADTVKMLSATQQTQEEIERTKQQLAFEVDRVKQESDMKFDEQKFEMDKLKRELEAKAAEIQKVRSSLQTSEMTGVHMNSSMAALQAEKDRLTQSISKKDAELSSLKKESQLKESSLQQERDRTIRELEELQGKLKEKLSREEQLQQKLLDEQFTLLQATVTEAENIIQDAVAKLDDPIHIS-CSSSPDYLISRAEATLGSVEKVQAGHSEYVKS---MKDAGGLVRALTMFSHLAADTIIN-GSATAHMAPTDHADRLTEQCKSCATQSLQYLKSLKSKASLRGADPTAIQAAVQKILRIGKDLRPKGLDVGKDELGDMVDKEMAATSAAIEEAVRRIDEMMSQTRKDATGVQLEVNERILNSCTDLMQAIRLLVLASTDLQKEIVEGGRGAASVREFYARNSRWTEGLISASKAVGWGATQMVDSADKVVLHTG----KYEELIVCSHEIAASTAQLVAASKVKADRGSKRLGNLQQASRHVNEMAAKVVASTKTGQDQVEDK----DTMDFSGLSLIKLKKEEMESQVKVLELETMLENERLRLGELRKKHYEIAGVPLEQLSEDNGLKASPASPK-PSSKPGLMKKPVLAQKPN--------IPPKTMLR-", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P33338-1", "uniprot_id": "SLA2_YEAST", "id": "P33338-1", "name": "Protein SLA2", "aln": "-----------------------MSRIDSDLQKALKKACSVEETAPKRKHVRACIVYTWDHQSSKAVFTTLKTLPLANDEVQLFKMLIVLHKIIQEGHPSALAEAIRDRDWIRSLGRVHSGGSSYSK---LIREYVRYLVLKLDFHAHHRGFNNGTFEYEEYVSLVSVSDPDEGYETILDLMSLQDSLDEFSQIIFASIQ-----SERRNTECKISALIPLIAESYGIYKFITSMLRAMHRQLNDAEGDAALQPLKERYELQHARLFEFYADCSSVKYLTTLVTIPKLPVDAPDVFLINDVDESKEIKFKKREPS----VTPARTPARTPTPTPPVVAEPAISPRPVSQRTTSTPTGYLQTMPTGATTGMMIPTATG----------------AANAIFPQATAQMQPDFWANQQAQFANEQNRLEQERVQQLQQQQAQQELFQQQLQKAQQDMMNMQLQQQNQHQNDLIALTNQYEK----------DQALLQQYDQRVQQLESEITTMDSTASKQLANKDEQLTALQDQLDVWERKYESLAKLYSQLRQEHLNLLPRFKKLQLKVNSAQESIQKKEQLEHKLKQKDLQMAELVKDRDRARLELERSINNAEADSAAATAAAETMTQDKMNPILDAILESGINTIQESVYNLDSPLSWSGPLTPPTFLLSLLESTSENATEFATSFNNLIVDGLAHGDQTEVIHCVSDFSTSMATLVTNSKAYAVTTLPQEQSDQILTLVKRCAREAQYFFEDLMSENLNQVGDEEKTDIVINANVDMQEKLQELSLAIEP--LLNIQSVKSNKETNPHSELVATADKIVKSSEH----LRVDVPKPLLSLALMIIDAVVALVKAAIQCQNEIATT--TSIPLNQFYLKNSRWTEGLISAAKAVAGATNVLITTASKLITSEDNENTSPEQFIVASKEVAASTIQLVAASRVKTSIHSKAQDKLEHCSKDVTDACRSLGNHVMGMIEDDHSTSQQQQPLDFT--SEHTLKTAEMEQQVEILKLEQSLSNARKRLGEIRRHAYYNQDDD------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .:::. ::.** . *:. *.**.* *: * .:.: :.:: ***... : :*: ****::::** ..* : * . * . * : . *: :.: * *:.** :* : . :* :. .: :* :: :: ::::. *. .::: :: .:: * . :*:::.** :* :. :*:: ..:: :* * ** ::*:. *. * * . .: *:. *: **:** ..*:.: . : * : . : .. . .. . : ::: ..*.. . : :. . .::: : :*:: . *** * * : : : : : :: . : :::* : : :: .* * :: : :** :: . :. :: ::. :: *: :* . : . . . .: . : *. : : : ::: :. :. . . .:.. : : . *: .:* . .. :*::* :**.*: :.* :*:* : : . . .. : : . * :: .:: ** * : * . : * : :*:: : *. .: . .* .: : :: : : :.*: .* : * : . : : . .: * :.::..:.: ::::* : :*. . ::.*: ** :: . *:**. : . .:** :***********:***. .:. :: :*.*:: . . *::**.*:*:**** ******:**:. * ..*:..*: *.: . .: . :: .. :.:**: * .**. *** **.:*:** *. * ****:*:: * . ", "identical_positions": 160, "similar_positions": 348, "identity": "14.64%" }, { "cls_id": "homologset.agr.MGI:1352507", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A6H6A9-1", "uniprot_id": "RBG1L_MOUSE", "id": "A6H6A9-1", "name": "Rab GTPase-activating protein 1-like", "aln": "----MEVRASFQKVSGS------SDSVATLNSEEFVLVSQHTDATSIKD-------------------DGKPQLKIASNGDE-QLEKAMEEILRDSEKGQSGLPVDCQGSSEISDCPFGDVPASQTT-----------------KPPLQLILDPSNTEISTPR-------PSSPSRFPEED---------------------SVLFNKLTYLGCMKVSSPRSEVEALRAMATMRASSQ-YPFAVTLYVPNVPEGSVRIIDQSSNVEIASFPIYKVLFCARGHDGTAESNCFAFTESSHGSEEFQIHVFSCEIKEAVSRILYSFCTAFKRSSRQVSDVKDSVIP---TPDSDV---------FTFSVSLEVKEDDGKGNFSPVPKDRDKFYFKIKQGIEKKVVITVQQLSN---KELAIERCFGMLLSPGRNVKNSDMHLLDMESMG-----------------KSYDGRAYVITGMWNPNAPIFLALNEETPKDKRVYMTVAVDMVVTEVVEPVRFLLETVVRVYPANER---FWYFSRKTFTETFFMRLKQSE----GKGHSSAGDAIYEVVSLQRES-----DKEEPITPTSAGGPMSPQEDEAEEES---DNELSSGTGDVSKDCPEKILYSWGELLGRWHNNLGGRPKGLFTLVKSGVPEALRAEVWQLLAGCHDNQEMLDKYRILITKDSAQESVITRDIHRTFPAHDYFKDTGGDGQESLYKICKAYSVFDEDIGYCQGQSFLAAVLLLHMPEEQ-AFCVLVTIMYGYKLRDLYRNNFEDLHCKFYQLEKLMQEQLPDLYSHFCDLNLEAHMYASQWFLTLFTAKFPLCMVFHIIDLLLCEGLNIIFHVALALLKTSKEDLLQADFEGALKFFRVQLPKRYRAEENARR---LMEQACNIKVPTKKLKKYEKEYQAMRENQLQQEDPMDRYK---------------FVYL-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8I6AXS5-1", "uniprot_id": "A0A8I6AXS5_RAT", "id": "A0A8I6AXS5-1", "name": "Rab GTPase-activating protein 1-like", "aln": "----MEVRASLQKVSGS------PDSAATLNSEEFVLVPQHTDDTSIKD-------------------DGKPQLKIASNGDE-QLEKAMEEILRDSEKGQSSLPVDGQGSSEISDHSFGDVPASQSN-----------------KPPLQLILDPSNTEISTPR-------PSSPSGFPEED---------------------SVLFNKLTYLGCMKVSSPRSEGEALRAMATMRASSQ-YPFAVTLYVPNVPEGSVRIIDQSSNVEIASFPIYKVLFCARGHDGTTESNCFAFTESSHGSEEFQIHVFSCEIKEAVSRILYSFCTAFKRSSRQVSDVKDSIIP---TPDSDV---------FTFSVSLEVKEDDGKGNFSPVPKDRDKFYFKIKQGIEKKVVITVQQLSN---KELAIERCFGMLLSPGRNVKNSDMHLLDMESMG-----------------KSYDGRAYVITGMWNPNAPIFLALNEETPKDKRVYMTVAVDMVVTEVVEPVRFLLETVVRVYPANER---FWYFSRKTFTETFFMRLKQSE----GKGHSSAGDAIYEVVSLQRES-----DKEEPVTPTSGGGPASPQEDEAEEES---DNELSSGTGDVSKDCPEKILYSWGELLGRWHNNLNARPKGLPTLVKSGVPEALRAEVWQLLAGCHDNQAMLDKYRILITKDSAQESVITRDIHRTFPAHDYFKDTGGDGQESLYKICKAYSVYDEDIGYCQGQSFLAAVLLLHMPEEQ-AFCVLVNIMYKYKLRDLYKNNFEDLHCKFYQLEKLMQEQLPDLYSHFCDLNLEAHMYASQWFLTLFTAKFPLCMVFHIIDLLLCEGLNIIFHVALALLKTSKEDLLQADFEGALKFFRVQLPKRYRAEENARR---LMEQACNIKVPTKKLKKYEKEYQAMRENQLQQEDPMDRYK---------------RENRRLQEASMRLEQENDDLAHELVTSKIALR------NDLDQAEDKADVLSKELLFTKQRLVETEEEKRKQEEETAQLKEVFRKQLEKAEYEIKKTTAIIAEYKQICSQLSTR--LEKQQAASKEELEAVKGKMMACKHCSDIFSKEGAGKPVAISREDQGLEADDEKDSLKKQLREMELELAQTKLQLVEAKCKIQELEHQRGALMNEIQAAKN------SWFSKTLNSIKTATGTQPLQPPQAPQPPKEST-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q5R372-1", "uniprot_id": "RBG1L_HUMAN", "id": "Q5R372-1", "name": "Rab GTPase-activating protein 1-like", "aln": "----MEVRASLQKVSGS------SDSVATMNSEEFVLVPQYADDNSTKH-------------------EEKPQLKIVSNGDE-QLEKAMEEILRDSEKRPSSLLVDCQSSSEISDHSFGDIPASQTN-----------------KPSLQLILDPSNTEISTPR-------PSSPGGLPEED---------------------SVLFNKLTYLGCMKVSSPRNEVEALRAMATMKSSSQ-YPFPVTLYVPNVPEGSVRIIDQSSNVEIASFPIYKVLFCARGHDGTTESNCFAFTESSHGSEEFQIHVFSCEIKEAVSRILYSFCTAFKRSSRQVSDVKDSVIP---TPDSDV---------FTFSVSLEVKEDDGKGNFSPVPKDRDKFYFKLKQGIEKKVVITVQQLSN---KELAIERCFGMLLSPGRNVKNSDMHLLDMESMG-----------------KSYDGRAYVITGMWNPNAPVFLALNEETPKDKQVYMTVAVDMVVTEVVEPVRFLLETVVRVYPANER---FWYFSRKTFTETFFMRLKQSE----GKGHTNAGDAIYEVVSLQRES-----DKEEPVTPTSGGGPMSPQDDEAEEES---DNELSSGTGDVSKDCPEKILYSWGELLGKWHSNLGARPKGLSTLVKSGVPEALRAEVWQLLAGCHDNQAMLDRYRILITKDSAQESVITRDIHRTFPAHDYFKDTGGDGQESLYKICKAYSVYDEDIGYCQGQSFLAAVLLLHMPEEQ-AFCVLVKIMYDYGLRDLYRNNFEDLHCKFYQLERLMQEQLPDLHSHFSDLNLEAHMYASQWFLTLFTAKFPLCMVFHIIDLLLCEGLNIIFHVALALLKTSKEDLLQADFEGALKFFRVQLPKRYRAEENARR---LMEQACNIKVPTKKLKKYEKEYQTMRESQLQQEDPMDRYK---------------FVYL-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AC58IFA0-1", "uniprot_id": "A0AC58IFA0_DANRE", "id": "A0AC58IFA0-1", "name": "", "aln": "----MDDSSSLGRVSGS------TESVSTVTSEEFVLVPPSAGGSPSSS-------------------EGRPRLKMSWNGSE-QLERAMEEVLDDVADGAG--AEQEKGCTQIR-------PPS---------------------------LDTAPHESSAAL-------LESPT-VPEEE---------------------SVQFSKLSYLGCTWVKAPRSETEAQKAMATLRAESA-IPIPVILHVPNGSDGCVRIVDQASGTEIASFPIYKVLFCARGCEGSVESDCFSFTESYRSSEDFQIHVFSCHIKEAVSRILYSFSTAFKRSAKAATEMQDSPLPL--SPDSDV---------FTFSVSLEVREDDGKGNFSPVPKDRDKYYFKLRQGVQKKVSVVVQQLNN---KELVIERCFGMLLSPGQKVRNSDMHLLDMESMG-----------------KNADGKAYVITGIWNPNTPAFQPLNEDTPKDKQVYMTVAVDLVVTEVVEPVRFLMEALVRVYPANER---FWYFSRKAFCETFYLKLKQGS----VKG--SQDDMMYEVVSLEKHS-----ECG---SQARGRLQSPTEEEEPEEDS---DSEISSGTGDVSKDCPEKILESWGGILNRWQGNLLTRPKGLSALVKPGIPEALRAEVWQLLSGCHNDQALLEQYRILITKESAQEAVITRDIHRTFPAHDYFKDSGGDGQDSLYKICKAYSVYDEEIGYCQGQSFLAAVLLLHMPEEQ-AFCVLVKIMFNYGLRELYRNNFEDLHCKFYQLERLLQELLPDLWSHFQELNLEAHMYASQWFLTLFTAKFPLCMVFHITDLLLCEGLNIIFNVALALLKTSKEDLLQADFEGALKFFRVQLPKRYRAAENARR---LMEQACNIKVPTKKLKKFEKEYQSLRESQLQQEDPIDRYQ---------------RENRRLQEASMRLEQENDDLAHELVTSKIALR------NDLDQAEDKADVLNKELLNTKQRLVETEEEKRRQEEETAQLKEVFRRELEKAEQEIKKTTAIIAEYKQICSQLSTR--LEKQQASTKEELDIVKAKVMACERCREVFSKDGPLQIPPVSQDNRDTDLDEEKDSLKAQLRELELELAQTKLQLVEAKCKIQELEHQRGVLMTEVQAAKN------SWFSKTLGSLKNSASNQSPSSPKEGP-------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A8JNN5-1", "uniprot_id": "A8JNN5_DROME", "id": "A8JNN5-1", "name": "", "aln": "MDDNLSTKSSESSITTSGEYEIVTDSNVASPMEQVKQVVNQEGTQPEVGGKPPTSLSALALSSPEAGGDRSPTLDMAHNRNLSDMQHEMTDALKDLELERGVAASGEKSAQRLPSHQQKSLTLPLTGSGGGSVDPEMRFPCTLFTPKSEETLDDASSSNRVGHSVFYDCIDASPACVEEKQDAMKPEKGDTTDEEVSEIDQGCTIFSGVTYLGAANINAPKSETEVYRIMGELNSGSKSVGLKITVSIPNCSEGLVVLHDAESNTIIATYEISSIILYYRGPVDTVENGCFAFTW-LHGDALFQCHVFRCHIPEAVNQVSACFQKAFQTYPPSMSCSLNSAVDMANSVTSDVSGNPLNTAGYEFIVSLEIRERVAKNSYAAVPRDRG--CFKLRANTDKEVCITVKQTPSNVLQPLHIERCFGVLVAPGKLVVQKDMHLIDMHSMGYIQPGGTGVATESDSNAQQSSSWPYTIRAEWKAQEKAFEQLNLESSKTN---LTVAVDIVMRRIQEPVRFVIETPVTIQSASEMRIMDHFMSKRPMTLRFYLHLKRTEESNWKVNSIDPSEEITEQPGHQQSSSLLKMGMNNLSRIVRSSSIASIEDDCPSDYSSDGDEPLLSGTGEVSKDCSQDTLDEWDPILREWDS--EKRPKNLAPLVRLGVPEALREKIWQKLANVEGRMEMNDKYKILITKETKCETVIQRDIHRTFPAHKCFKEIGGSGQDALFKVSKAYAVHDSEVGYCQGLSFIAASLLLHMPEED-AFCVLVALMYDYGLRDLYKAGFEVLYLRLYQLERLIKDQLPKLHEHFTACGIETHMYASQWFLTLYTARFPLCFVFHVLDVFLLDGLPVLFQVAVTLLSICESDLRQLDFEGILKYFRVTLPKKCRSSSQARK---VMKQACERKI--KKLKQYEEEFLLKKQHKERLEKEAQIYENRFGEERRKMQAEIDALNKQLTSAKERAVEKEKKHTGIIQEYKQIIQRQEQDMNTLSETLGKVMHMVSNCQDCQQQIDAGNDNAKSDDGKNRGQTDAMRNANEHPLGPLDPLNAASQRIRELELELAQAKLAQVEAECKNQDLNHQLSNTLSELQTNRNSWQPWLSKTFNSLQEKVTTRGGHRDNGSGGPMPSFQSYMGQAPTTLSEASSPSGNQEYKTFAFASVGGSPKLPSKFQATKLRNSIDSLRNIVVPLDTGKTLAENLKQQLQQ", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q04322-1", "uniprot_id": "GYL1_YEAST", "id": "Q04322-1", "name": "Probable GTPase-activating protein GYL1", "aln": "-----------------------MNSNEDIHEERIEVPRTPHQTQPEKD---------------------------------------------------------------------------------------------------------------------------------------------------------------------SDRIALRDEISVPEGDEKAYSDEK-----VEMATTNASSNFGSNESAKDGESIGAFSNPHEALMQS----KLREESQSKTILPSDDLSQQLETEESKVEEALKRITSPPLPPRADCIEESASALKSSLP----------------------------PVLAGNKNDQAPLDRP-------------------------------------QLPPRQVVNAETLHLKAPHGNA-------------------------------TPSKSPTSAVGNSS-------SSTPPTLPPRRIEDPLDLAAQKHFLASTFKRN-------------MLFYK-SEDNS-----------------------------------IKCDLDKNILNLKEDSKKINN---------------NEIPEEVSSFWLKVIGDYQNILINDIETLHFQLSRGIPAAYRLVVWQLVSYAKSK-------SFDPIYETYLTEMAPFDVQEFENQLKMMDEVPSEYVKRISNVLKAYLLFDPECEFSTDIAYIINMILDVCEEEANAFGLLVRLMKVYGLRLLFLPSASEIDILCYKFDRLVEEFYPEIHNHMVEKGVRSSMFLPGFFTTLFQKKLPTEIQPRIGDMVFLEGIDSIMRILATLLSNSRDHLLKMGFDDMLELLKSGLLDAYIKQNDGTRGDTLLSNECMDKLLQDSMMKVAITPKTMKKYSSEYEEIHRLDN---------------------------------------------------------EKEVQYKSITEKNLHLQKHVRKLENDYTSLNREHVTIANELVKNRLNIESVLNENNGYKLQILDLKKKLDSEKKKQVLGVYVPNDLKKDLEETMKKNTQVMDENLKLQDRISELERLIEEIKTANKNGTLFEYSNSKNNPLGAGWSGFKKVFK------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :* *.. . : :.* .. . : . : : .* ... . .. *.:: : . .. . : * .. * .. ..: **:.:: . : .* : . .. .* ** :.* : * . :** .. . ... :. .: :.. : .: :*: : : . . .. *: : . ::: . . :: .:. * :: :.. : * : *:* * * :** :: .. : :: : *::. . :.: .. . : :: *** :.* : :. . ::: :* ** ** :** :* * ** *: . . : *::::*::: *.: .*: .:.: *: . :* **: ::* : :: *:.: :*: ::.: :**. ....* : .*:. *: :: * . .:. : ::.: * *: ..: : :: . . *. : ", "identical_positions": 64, "similar_positions": 203, "identity": "5.3%" }, { "cls_id": "homologset.agr.MGI:1352508", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q68SB1-1", "uniprot_id": "STAU2_RAT", "id": "Q68SB1-1", "name": "Double-stranded RNA-binding protein Staufen homolog 2", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MANPKEKTPMCLVNELARFHSIQPQYKLLNESGPAHSKMFSVQLSLGEQTWESEGSSIKKAQQAVANKALTESTLPKPVQKPPKSNVNN-NPGSITPTVELNGLAMKRGE-------PAIYRPLDPKPFPNYRANYNFRG-------------------------------MYNQRYHCPMPKIFY----------------------------------VQLTVGNNEFFGEGKTRQAARHNAAMKALQALQNEPIPEKSPQNGESGKEMDDDKDANKSEISLVFEIALKRNMPVSFEVIKESGPPHMKSFVTRVSVGEFSAEGEGNSKKLSKKRAATTVLQELKKLPPLPVIEKP---------------------------------KLFFKKRPKTIIKAGPEYGQGMNPISRLAQIQQARKEKEPDYVLLSERG--MPRRREFVMQVKVGNEVATGTGPNKKIAKKNAAEAMLLQLGYKASTSLQDQLDKTGENKGWSGPKPGFPEPANNTP-----------------------------KGILHLSPDVYQEMEASRHRVTSGTTLGYLSPKDMNQPSSSFFSVESPSPTSSAPAARELLMNGTSPAAEAIGLKGS--------------------SPTPPCSSVQPSKQLEYLARIQGF--------------------------------------QAALSALKQFSEQGLESIDGVVNVENGSLEKQAKHLREKADNNQANPGSITQDCKKSKSVI", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8CJ67-1", "uniprot_id": "STAU2_MOUSE", "id": "Q8CJ67-1", "name": "Double-stranded RNA-binding protein Staufen homolog 2", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MANPKEKTPVCLVNELARFHSIQPQYKLLNESGPAHSKMFSVQLSLGEQTWESEGSSIKKAQQAVANKALTESTLPKPVQKPPKSNVNN-NPGSITPTVELNGLAMKRGE-------PAIYRPLDPKPFPNYRANYNFRG-------------------------------MYNQRYHCPMPKIFY----------------------------------VQLTVGNNEFFGEGKTRQAARHNAAMKALQALQNEPIPEKSPQNGESGKEMDDDKDANKSEISLVFEIALKRNMPVSFEVIKESGPPHMKSFVTRVSVGEFSAEGEGNSKKLSKKRAATTVLQELKKLPPLPVVEKP---------------------------------KLFFKKRPKTIVKAGPDYGQGMNPISRLAQIQQARKEKEPDYILLSERG--MPRRREFVMQVKVGNEVATGTGPNKKIAKKNAAEAMLLQLGYKASTSLQDPLDKTGENKGWSGPKPGFPEPTNNTP-----------------------------KGILHLSPDVYQEMEASRHRVTSGTTLSYLSPKDMNQPSSSFFSVS-PSSTSSATVARELLMNGTSPTAEAIGLKGS--------------------SPTSPCSSVQPSKQLEYLARIQGF--------------------------------------QAALSALKQFSEQGLESIDGAVNVEKGSLEKQAKHLREKADNNQAKPASISQDCKKSKSAI", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9NUL3-1", "uniprot_id": "STAU2_HUMAN", "id": "Q9NUL3-1", "name": "Double-stranded RNA-binding protein Staufen homolog 2", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MANPKEKTAMCLVNELARFNRVQPQYKLLNERGPAHSKMFSVQLSLGEQTWESEGSSIKKAQQAVANKALTESTLPKPVQKPPKSNVNN-NPGSITPTVELNGLAMKRGE-------PAIYRPLDPKPFPNYRANYNFRG-------------------------------MYNQRYHCPVPKIFY----------------------------------VQLTVGNNEFFGEGKTRQAARHNAAMKALQALQNEPIPERSPQNGESGKDVDDDKDANKSEISLVFEIALKRNMPVSFEVIKESGPPHMKSFVTRVSVGEFSAEGEGNSKKLSKKRAATTVLQELKKLPPLPVVEKP---------------------------------KLFFKKRPKTIVKAGPEYGQGMNPISRLAQIQQAKKEKEPDYVLLSERG--MPRRREFVMQVKVGNEVATGTGPNKKIAKKNAAEAMLLQLGYKASTNLQDQLEKTGENKGWSGPKPGFPEPTNNTP-----------------------------KGILHLSPDVYQEMEASRHKVISGTTLGYLSPKDMNQPSSSFFSIS-PTSNSSATIARELLMNGTSSTAEAIGLKGS--------------------SPTPPCSPVQPSKQLEYLARIQGF--------------------------------------QAALSALKQFSEQGLDPIDGAMNIEKGSLEKQAKHLREKADNNQAPPGSIAQDCKKSNSAV", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q7ZW47-1", "uniprot_id": "STAU2_DANRE", "id": "Q7ZW47-1", "name": "Double-stranded RNA-binding protein Staufen homolog 2", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MANPKEKTPMCLVNELARFNRIQPQYKLLNEKGPAHAKIFTVQLCLGNQVWESEGSSIKKAQHSTATKALAESSLPRPPPRSPKADSNS-NPGSITPTVELNGLAMKRGE-------PAIYRPLDPKPIPNYRANYNFRG-------------------------------MFNQRYHYPVPKVFY----------------------------------VQLTVGNNEFIGEGRTRQAARHNAAMKALQALKNEPIPERPPQCSEEKKETEENSDASKSEISLVYEIALKRNLPVNFEVLKESGPPHMKSFLTRVTVGEFSAEGEGNSKKLSKKRAALSILQELKKLPVLPVVEKP---------------------------------KVHYKKRPKTILKTGPEYGQGMNPISRLAQIQQAKKEKEPEYMLLSERG--MPRRREFIMQVKVGTEVTTGTGPNKKVAKRNAAEAMLLQLGYKASTPLQNTPEKMD-NKGWNGQRAAFPETTSNTQ-----------------------------KGILHLSPDVYQEMEASRNKGVPGAPGNFPTAKEIGQGSAGPFCTP--SVGNTATIAKELLLSGTSPTAEALVLKGK--------------------APALACGSIQPSQQLEYLAHIQGFQVQYSDRQTDKEFMTYLTLSPVQMTFHGIGSSIPASHDQAALSALKQLSEQGLDPVDGPIKVENGSCDIQAKRLAERTESKPTNSGTTAQDCKDSKAVV", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P25159-1", "uniprot_id": "STAU_DROME", "id": "P25159-1", "name": "Maternal effect protein staufen", "aln": "MQHNVHAARPAPHIRAAHHHSHSHAHMHLHPGMEQHLGPSLQQQQQPPPPPQQPPHRDLHARLNHHHLHAQQQQQQQTSSNQAGAVAAAGAAYHHGNINSNSGSNISSNSNQMQKIRQQHQHLSSSNGLLGNQPPGPPPQAFNPLAGNPAALAYNQLPPHPPHHMAAHLGSYAAPPPHYYMSQAKPAKYNHYGSNANSNSGSNNSNSNYAPKAILQNTYRNQKVVVPPVVQEVTPVPEPPVTTNNATTNSTSNSTVIASEPVTQEDTSQKPETRQEPASADDHVSTGNIDATGALSNEDTSSSGRGGKDKTPMCLVNELARYNKITHQYRLTEERGPAHCKTFTVTLMLGDEEYSADGFKIKKAQHLAASKAIEETMYKHPPPKIRRSEEGGPMRTHITPTVELNALAMKLGQRTFYLLDPTQIPPTDSIVPPEFAGGHLLTAPGPGMPQPPPPPAYALRQRLGNGFVPIPSQPMHPHFFHGPGQRPFPPKFPSRFALPPPLGAHVHHGPNGPFPSVPTPPSKITLFVGKQKFVGIGRTLQQAKHDAAARALQVLKTQAIS-----ASEEALEDSMDEGDKKSPISQVHEIGIKRNMTVHFKVLREEGPAHMKNFITACIVGSIVTEGEGNGKKVSKKRAAEKMLVELQKLPPLTPTKQTPLKRIKVKTPGKSGAAAREGSVVSGTDGPTQTGKPERRKRLNPPKDKLIDMDDADNPITKLIQLQQTRKEKEPIFELIAKNGNETARRREFVMEVSASGSTARGTGNSKKLAKRNAAQALFELLEAVQVTPTNETQSSEECSTSATMSAVTAPAVEATAEGKVPMVATPVGPMPGILILRQNKKPAKKRDQIVIVKSNVESKEEEANKEVAVAAEENSNNSANSGDSSNSSSGDSQATEAASESALNTSTGSNTSGVSSNSSNVGANTDGNNHAESKNNTESSSNSTSNTQSAGVHMKEQLLYLSKLLDF--------------------------------------EVNFSDYPKGNHNEFLTIVTLSTHPPQICHGVGKSSEESQNDAASNALKILSKLGLNNAMK", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . *:**.:********:: : **:* :* ****.* *:* * **:: :.::* .*****: .*.**: *: :* : ::: .. ********.**** *: *: * *. *:: ..: : . *. : :* * : * : * **:::*.* *:* * *:*:** :***.*:.:.*. .*. : . :.. .** ** *.**.:***:.* *:*::*.**.***.*:* **.: :*****.**:****** .:* **:*** *. ::. * :** :. . : .:. ***::* *:**::***** : *:::.* .*****:*:*... ..: *** .**:**:***:*:: * * :: .. ... . * .: . *: :..:* .: * :.:. .: . .. : .: * . : : . . ..** .:. * :. .. :: .:** **::: .* :. :* : ..: : .: . . .* * :. : . . .. .:: ", "identical_positions": 171, "similar_positions": 200, "identity": "16.0%" }, { "cls_id": "homologset.agr.MGI:1352630", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q63563-1", "uniprot_id": "ABCC9_RAT", "id": "Q63563-1", "name": "ATP-binding cassette sub-family C member 9", "aln": "MSLSFCGNNISS--YNIYHGVLQNPCFVDALNLVPHVFLLFITFPILFIGWGSQSSKVQIHHNTWLHFPGHNLRWILTFALLFVHVCEIAEGIVSDSQRASRHLHLFMPAVMGFVATTTSIVYYHNIETSNFPKLLLALFLYWVMAFITKTIKLVKYWQLGWGMSDLR------FCITGVMVILNGLLMAVEINVIRVRRYVFFMNPQKVKPPEDLQDLG-VRFLQPFVNLLSKATYWWMNTLIISAHRKPIDLKAIGKLPIAMRAVTNYVCLKEAYEEQKKKAADHPNRTPSIWLAMYRAFGRPILLSSTFRYLADLLGFAGPLCISGIVQRVN---------------------------------EPKNNT---TRFSETLSSKEFLENAHVLAVLLFLALILQRTFLQASYYVTIETGINLRGALLAMIYNKILRLSTSNLSMG--------------------------------------EMTLGQINNLVAIETNQLMWFLFLCPNLWAMPVQIIMGVILLYNLLGSSALVG-AAVIVLLAPIQYFIATKLAEAQKSTLDYSTERLKKTNEILKGIKLLKLYAWEHIFCKSVEETRMKELSSLKTFALYTSLSIFMNAAIPIAAVLATFVTHAYASGN---NLKPAEAFASLSLFHILVTPLFLLSTVVRFAVKAIISVQKLNEFLLSDEIGEDSWRTG---------------------------------------------------EGTLPFESCKKHT-GVQSKPINRKQPGRYHLDNYEQ-------------------------------------ARRLRPAETEDVAIKVTNGYFSWGSG----LATLSNIDIRIPTGQLTMIVGQVGCGKSSLLLAILGEMQTLEGKVYWNNVNESEPSFEA------------TRSRSRYSVAYAAQKPWLLNATVEENITFGSSFNRQRYKAVTDACSLQPDIDLLPFGDQTEIGERGINLSGGQRQRICVARALYQNTNIVFLDDPFSALDIHLSDHLMQEGILKFLQDDKRTVVLVTHKLQYLTHADWIIAMKDGSVLREGTLKDIQTKDVELYEHWKTLMNRQDQE---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------LEKDMEAD-QTTLERKTLRRAMYSR-------------------------------------------EAKAQMEDEDEEEEEEEDEDDNMSTVMRLRT--------------------------------------------KMPWKTCWWYLTSGGFFLLFLMIFSKLLKHSVIVAIDYWLATWTSEY-------SIND---------------PGKADQTFYVAGFSILCGAGIFLCLVTSLTVEWMGLTAAKNLHHNLLNKIILGPIRFFDTTPLGLILNRFSADTNIIDQHIPPTLESLTRSTLLCLSAIGMISYATPVFLIALAPLGVAFYFIQKYFRVASKDLQELDDSTQLPLLCHFSETAEGLTTIRAFRHETRFKQRMLELTDTNNIAYLFLSAANRWLEVRTDYLGACIVLTASIASISGSSNSG------------------------------------LVGLGLLYALTITNYLNWVVRNLADLEVQMGAVKKVNSFLTMESENYEGTMDP-------------------------------------------------------------------------------------------------------------------------------------------------SQVPEHWPQEGEIKIHDLCVRYENNLKPVLKHVKAYIKPGQKVGICGRTGSGKSSLSLAFFRMVDIFDGKIVIDGIDISKLPLHTLRSRLSIILQDPILFSGSIRFNLDPECKCTDDRLWEALEIAQLKNMVK-SLPGGLDATVTEGGENFSVGQRQLFCLARAFVRKSSILIMDEATASIDMATENILQKVVMTAFADRTVVTIAHRVSSIMDAGLVLVFSEGILVECDTGPNLLQHKNGLFSTLVMTNK---", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P70170-1", "uniprot_id": "ABCC9_MOUSE", "id": "P70170-1", "name": "ATP-binding cassette sub-family C member 9", "aln": "MSLSFCGNNISS--YNIYYGVLQNPCFVDALNLVPHVFLLFITFPILFIGWGSQSSKVQIHHNTWLHFPGHNLRWILTFALLFVHVCEIAEGIVSDSHRASRHLHLFMPAVMGFVATTTSIVYYHNIETSNFPKLLLALFLYWVMAFITKTIKLVKYWQLGWGVSDLR------FCITGVMVILNGLLMAVEINVIRVRRYVFFMNPQKVKPPEDLQDLG-VRFLQPFVNLLSKATYWWMNTLIISAHRKPIDLKAIGKLPIAMRAVTNYVCLKEAYEEQKKKAADHPNRTPSIWLAMYRAFGRPILLSSTFRYLADLLGFAGPLCISGIVQRVN---------------------------------EKTNTTR--EMFPETLSSKEFLENAHVLAVLLFLALILQRTFLQASYYVTIETGINLRGALLAMIYNKILRLSTSNLSMG--------------------------------------EMTLGQINNLVAIETNQLMWFLFLCPNLWAMPVQIIMGVILLYNLLGSSALVG-AAVIVLLAPIQYFIATKLAEAQKSTLDYSTERLKKTNEILKGIKLLKLYAWEHIFCKSVEETRMKELSSLKTFALYTSLSIFMNAAIPIAAVLATFVTHAYASGN---NLKPAEAFASLSLFHILVTPLFLLSTVVRFAVKAIISVQKLNEFLLSDEIGEDSWRAG---------------------------------------------------EGTLPFESCKKHT-GVQSKPINRKQPGRYHLDSYEQ-------------------------------------ARRLRPAETEDIAIKVTNGYFSWGSG----LATLSNIDIRIPTGQLTMIVGQVGCGKSSLLLAILGEMQTLEGKVYWNNVNESEPSFEA------------TRSRSRYSVAYAAQKPWLLNATVEENITFGSPFNRQRYKAVTDACSLQPDIDLLPFGDQTEIGERGINLSGGQRQRICVARALYQNTNIVFLDDPFSALDIHLSDHLMQEGILKFLQDDKRTVVLVTHKLQYLTHADWIIAMKDGSVLREGTLKDIQTKDVELYEHWKTLMNRQDQE---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------LEKDMEAD-QTTLERKTLRRAMYSR-------------------------------------------EAKAQMEDEDEEEEEEEDEEDNMSTVMRLRT--------------------------------------------KMPWKTCWWYLTSGGFFLLFLMIFSKLLKHSVIVAIDYWLATWTSEY-------SINH---------------PGKADQTFYVAGFSILCGAGIFLCLVTSLTVEWMGLTAAKNLHHNLLNKIILGPIRFFDTTPLGLILNRFSADTNIIDQHIPPTLESLTRSTLLCLSAIGMISYATPVFLVALAPLGVAFYFIQKYFRVASKDLQELDDSTQLPLLCHFSETAEGLTTIRAFRHETRFKQRMLELTDTNNIAYLFLSAANRWLEVRTDYLGACIVLTASIASISGSSNSG------------------------------------LVGLGLLYALTITNYLNWVVRNLADLEVQMGAVKKVNSFLTMESENYEGTMDP-------------------------------------------------------------------------------------------------------------------------------------------------SQVPEHWPQEGEIKIHDLCVRYENNLKPVLKHVKAYIKPGQKVGICGRTGSGKSSLSLAFFRMVDIFDGKIVIDGIDISKLPLHTLRSRLSIILQDPILFSGSIRFNLDPECKCTDDRLWEALEIAQLKNMVK-SLPGGLDATVTEGGENFSVGQRQLFCLARAFVRKSSILIMDEATASIDMATENILQKVVMTAFADRTVVTIAHRVSSIVDAGLVLVFSEGILVECDTGPNLLQHKNGLFSTLVMTNK---", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O60706-1", "uniprot_id": "ABCC9_HUMAN", "id": "O60706-1", "name": "ATP-binding cassette sub-family C member 9", "aln": "MSLSFCGNNISS--YNINDGVLQNSCFVDALNLVPHVFLLFITFPILFIGWGSQSSKVQIHHNTWLHFPGHNLRWILTFALLFVHVCEIAEGIVSDSRRESRHLHLFMPAVMGFVATTTSIVYYHNIETSNFPKLLLALFLYWVMAFITKTIKLVKYCQSGLDISNLR------FCITGMMVILNGLLMAVEINVIRVRRYVFFMNPQKVKPPEDLQDLG-VRFLQPFVNLLSKATYWWMNTLIISAHKKPIDLKAIGKLPIAMRAVTNYVCLKDAYEEQKKKVADHPNRTPSIWLAMYRAFGRPILLSSTFRYLADLLGFAGPLCISGIVQRVN---------------------------------ETQNGTNNTTGISETLSSKEFLENAYVLAVLLFLALILQRTFLQASYYVTIETGINLRGALLAMIYNKILRLSTSNLSMG--------------------------------------EMTLGQINNLVAIETNQLMWFLFLCPNLWAMPVQIIMGVILLYNLLGSSALVG-AAVIVLLAPIQYFIATKLAEAQKSTLDYSTERLKKTNEILKGIKLLKLYAWEHIFCKSVEETRMKELSSLKTFALYTSLSIFMNAAIPIAAVLATFVTHAYASGN---NLKPAEAFASLSLFHILVTPLFLLSTVVRFAVKAIISVQKLNEFLLSDEIGDDSWRTG---------------------------------------------------ESSLPFESCKKHT-GVQPKTINRKQPGRYHLDSYEQS------------------------------------TRRLRPAETEDIAIKVTNGYFSWGSG----LATLSNIDIRIPTGQLTMIVGQVGCGKSSLLLAILGEMQTLEGKVHWSNVNESEPSFEA------------TRSRNRYSVAYAAQKPWLLNATVEENITFGSPFNKQRYKAVTDACSLQPDIDLLPFGDQTEIGERGINLSGGQRQRICVARALYQNTNIVFLDDPFSALDIHLSDHLMQEGILKFLQDDKRTLVLVTHKLQYLTHADWIIAMKDGSVLREGTLKDIQTKDVELYEHWKTLMNRQDQE---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------LEKDMEAD-QTTLERKTLRRAMYSR-------------------------------------------EAKAQMEDEDEEEEEEEDEDDNMSTVMRLRT--------------------------------------------KMPWKTCWRYLTSGGFFLLILMIFSKLLKHSVIVAIDYWLATWTSEY-------SINN---------------TGKADQTYYVAGFSILCGAGIFLCLVTSLTVEWMGLTAAKNLHHNLLNKIILGPIRFFDTTPLGLILNRFSADTNIIDQHIPPTLESLTRSTLLCLSAIGMISYATPVFLVALLPLGVAFYFIQKYFRVASKDLQELDDSTQLPLLCHFSETAEGLTTIRAFRHETRFKQRMLELTDTNNIAYLFLSAANRWLEVRTDYLGACIVLTASIASISGSSNSG------------------------------------LVGLGLLYALTITNYLNWVVRNLADLEVQMGAVKKVNSFLTMESENYEGTMDP-------------------------------------------------------------------------------------------------------------------------------------------------SQVPEHWPQEGEIKIHDLCVRYENNLKPVLKHVKAYIKPGQKVGICGRTGSGKSSLSLAFFRMVDIFDGKIVIDGIDISKLPLHTLRSRLSIILQDPILFSGSIRFNLDPECKCTDDRLWEALEIAQLKNMVK-SLPGGLDAVVTEGGENFSVGQRQLFCLARAFVRKSSILIMDEATASIDMATENILQKVVMTAFADRTVVTIAHRVSSIMDAGLVLVFSEGILVECDTVPNLLAHKNGLFSTLVMTNK---", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M2BBT3-1", "uniprot_id": "A0A8M2BBT3_DANRE", "id": "A0A8M2BBT3-1", "name": "", "aln": "MALSFCGNDRDSNAYSVDNGVLDNGCFVDALNLVPHVFLLFITFPILFIGWGSQSSKVQIHHNTWLHFPGHNMRWILTFTLLFVHVCEIAEGIVSNTQMESNHLHLFMPAFMGFIAATTSVVYYHNIETANFPKLLLALFIYWILAFITKMIKLWKFAEASLGVQHLR------FCITALLVVLYGLLMAVEINVIRVRKYVFFANPQRVKPPEDLQDLG-VRFLQPFVNLLSKATYWWMNPLIIGAHKRPIELKKIGKLPIAMRALTNYLRLKDSYEEQRQNTED-PEKSPSIWKSMYRAFGGSILLSSTFRYMADLLGFAGPLCISGIVEHLHNS----------------------------TEIDRTNKTGNMTFGVYFMSSTELLQNTSVLAVLLFLALVLQRTFLQASYYVTIETGINLRGALLAMIYNKILRLSTSNMSMG--------------------------------------EMTLGQINNLVAIETNQLMWFLFLCPNLWAMPVQIIMGVILLYYLLGNSALIG-AGVILLLAPVQYLIATKLADIQKSTLDYSTDRLKKTTEILKGIKLLKLYAWENIFCDRVEETRGKELTSLKTFALHTSMSIFMNAAIPIAAVLATFVTHAYIEED---RLSPAKAFASLALFHILVTPLFLLSTVVRFAVKALVSVQKLSEFLQSDEIGDDSWRNG---------------------------------------------------DMCMSLEVGKKYKYQGDTKAINRK--GRYRMDNYEQPV-----------------------------------RRQLRPSETEDVAVQVNDGFFTWGSN----LSTLSDINIRIPTGQLTMIVGQVGCGKSSLLLAMLGEMQTISGKVYWSKLPDCEILFDGNISGHDMELSHEERSKNRYSVAYATQKSWLLNATVEENITFGSPFNKQRYKAVIDACSLQPDIDLLPFGDQTEIGERGINLSGGQRQRICVARALYQNTNIVFLDDPFSALDIHLSDHLMQEGILKFLQDDKRTVVLVTHKLQYLIHADWIIAMKDGSVLREGTLKDIQTHDVELYEHWKTLMNRQDQE---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------LEKDTDLESQTTLERKTLRRAFYSR-------------------------------------------EAKNHVDDEDEEEEVEEEDDDNMSTTTSRRS--------------------------------------------KIPWKMCCCYLSSGGFLMVFLMVSSKLAKHSVMVAIDYWLAAWTSSN-------PHNQSFVNSSFNHTLNDDATQIAEHRSYVPVFIILCAAAIALCLITSLTVEFLGVAAATNLHHNLLNKIIHAPIRFFDVTPLGQILNRFSADTNIIDQHIPPTLESLTRSTLLCLSAIGVIAFVTPAFLIALVPLAVAFYFIQKYFRVASKDLQELDDSTQLPLLCHFSETAEGLTTIRAFRHEARFKQRMLELTDTNNTAYLFLSAANRWLEVRTDYLGAVIVLTAAVAAIWSTSPSG------------------------------------LVGLGLTYALTLTNYLNWVVRNLADLEVQMAAVKKVNSFLSTESENYEGSMDV-------------------------------------------------------------------------------------------------------------------------------------------------SQVPEDWPQHGEITIHDLCVRYDSMLKPVLKHVNAHINPGQKVGICGRTGSGKSSLSLAFFNMVDVFEGKIVIDGIDICKLPLQTLRSRLSIILQDPVLFSGSIRLNLDPERTCTDDRLWEALEIAQLKNMVK-ALPGGLDAVVTEGGENFSVGQRQLFCLARAFVRKSSILIMDEATASIDMATENILQKVVMTAFADRTVVTIAHLVSSILEAEQVLVFSSGILVENDSAINLLAQEDSLFGILVRTHK---", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VL32-1", "uniprot_id": "SUR_DROME", "id": "Q9VL32-1", "name": "ATP-binding cassette sub-family C member Sur", "aln": "MKQLFNIIHCDHLNGHVRSIYDNLNTDICGIDRVRRVFTFFSIFLLLFG-LMFVCSRYKKCHKTLLTFHNG--RAAISLLLLALNSFDLARIFLPHQNVRNLNRLFQSSPRDLNYLVVIGSGELWNALFSTLLTLMLMLYHRMVERKKATVFLYASTAVEALTFALLSNELFELVRYEDFLELQTCLVAMSAMCMVSLAMLDGLTVYKECYHDDYLDDYGKIGYKHSMATFYSKSCFWWLTPLLWLGYKEPLELEDLGQMKLEDSARSHYDHFLYIYTEKKK----KSNSSPSLWYCYIKNSWQMFALGGILKLAGDLFALIGPLAIQKIVEYIEQLYAQASEPPAKSPGNEVANVLLSTSRILGTEFDEVFGTNIDKVRIYSSTWSDLLANGWCIAWIVLLAAITQGALSQASTHILNMTGIRIKTSLQGLIYRKSLLLNADGGCDSSDSAGQVQSTSSTSDEKQKNDDSMATPEHVDNPSEPNISHDIGSITNHMTEDTRNIMEFFLIIHYAWAIPFKIAVVIYLLYMNLGISAVIGSIACIVIMTPLQFFIGNAMSKNAEVIAGYTDERLKRIHDTLVGIKVIKLNAWDEVFLKKIQEARRKELKYLNKDATFWTLMAVLTHIATVLITFVTLGVYVWLHRDQEFDLNASRLFSSLALFQQLTVPLLIFPITVPIIIAARVSTRRLERFLKSSEIQKQFEGIRNMARILSKSDASLDMYETQEKSNMTMRTAQAENRLNEKRLAQKSQTPELATNSTPLLQNAEESAEDISPSTVQELGHNKLVQQRRELLRNTPYVAIRPPKMRGSVMERPVEFSVIRARNTDSWRRDSLLLKMPDDIAVSINDGLFTWQPQSQMPVVQLHVPGIIVPKGKLTIVVGKNGSGKTSLLSALLMEMPLLAGNMFWHKT---------------------------CTISYVSQQPWLLNDTIRENILFGESFRPKRYDFVLEACALKPDIELMPRGDLSIIGERGINISGGQRQRIAIARAIYSSANVVIMDDPLASLDNEVGEHIFQHCIREMLQKSNRTFILVTQQLHRIKEAEYLIAIKDGRVEACGSYADIELMQPRITAEWNAIIAMAKAKNDNPSQNPGEKTAGERWKLLKNVSKLGLQRSISVTMDANVACHADAIDGSGCISVANMQSNVVEEDDQVSVSYPIGNASCGGFNLQRKRSSIYGSRHLMYDVPLPIDECQGDDVIMRPRRRHTLGRRGSRNTNSSHRLSGLSTLTATSESSSISGDVLSRSVLATSCSSYAESSVDGGDLATAAPEPRVQSWQPPQHVTHHQPLSRNASSPPAMEVANPDVKKSEEARRSNTSSESPLDDHVRGSFQQFLRRMSMRRSNKPKNHHHPLSATNSILSISEESPPVVHFPASILATDGNKNETQSEEKPKKCVNIDSKETTINCDDNCYSASDKELRANVTSSPADQEQHNERHVLAEVAGESGRESMPLARLAIDTERKYGKISDDIYLMYIRAAGLPIITIFFITALIWQCLRVYTDIWLQQWSNVHGRVASKG------------HVVLHPSEQDHEVTYYFRMYAAISCVCIIMALVSTPAGQYAGCNARRNLHDKLLQTILHKTLHFFQVTPLGRIVNRFSNDMAVIDKKIAATGQRLLQFTLLCLSAILINVTITPWILVLTLPICGAYYLIQKFYRCSARELQRIENATNSPVISHLSETIQGVTTIRAFNQQTRFTEILFKRLEANTIAYALLNTSHRWLGVSLDYLGGCIVFVATVTALTAASVSCRRHYEATTSPSASASPSPFETYAVTKSPSELRPSPSLVGLAINYTLLVPIYLNWVVKLLADMEMYAGSVERIAHYAQGQDADADADADADADVDADLDHEPSSNEDVSAEVDRSSQSDAGDKVYPGATTAAGDVDEDGDQQRIGGARGGGGDCGYRQGHENGAEANADKLNAGNVTGDGNHLNFHHPPATAGDKVEQATTKTSVIKDKQLPPQQDDKDKKVVLPNEPARKLERYQSVPISWPQRGDIHFDNVSLRYEGQKQNVISNLTLKIPAGQRIGICGRTGSGKSSLGLSLFGVLQTTRGHIYIDDVDIQRIRPDELRTRLSIIPQDVHLFNATIRENLDPHGYFQDLQLWNCLELAQLKEFVNGHLPLGLDTVICDGGLNLSAGHRQLLCLARAILRGSVCLVLDEATSVLDSSTESALLKAADLAFRGRTIITIAHRLTTILDYDRLIVLDQGRIVEDGNPRELQQLEGSVFRGLLEKGASKW", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* * . . : : : .:: * :** :* * :** .*: : *:* * * . * ::: ** :: ::*. ::.. . . : : .. .. . * :.: .*:* *: : :. : . . . * . .: : *: : :: : : :. : *:* * : : :.:..: **: :**:..*: .::.*::*: :*:: : * ::* : * *::: .: :**:* . : : *.. :: .**:.: ***.*. **: :. : * : .::* * :* :::** : * :: *** :: ***.:: :* .:**.* * *.:.. . . . :*.*.* :: :*.::* *::: **:*.:* : : *** ** **::* . *::::*:*::*.. ::. : .*: :***: : * ***::** **:.:* . ::*:* ***. *:. * . :: .:. .: .:.*: .:.: : *..:. *:**:**: *..**:::. .* : : * :*.::*..** *.** .: : :: :: ....::. .: : * * .:*:*:.:.:* *:* . : * .* :*.*:**::**: *.**:*** *:* ** : *::.* : :::*.:*:.**** *:.*** **..*. :**. * :**:*:***:*:* ** : *******:********.:***:*..:*:*::***:::** .:.:*::*. * ::**..:**.:***::*: : .*:::**:*** * *: **: : .: .*:::: . : *:.. . * *.* ::**: .: :.* :: :.:* : ::: :: *: *:. . *: :.*: :: ::. : * :.: * * ** *:. : *. : :. . * :.*::: : :: * * ***.:**:.*: .::**:.**** *:**** * :**::*..* : * : ******** : ** :*: *: *:*:***::* ::::**.::::*: *::.*:*** :*:******.:::**.: ::: ::*. ** :*.:::*** * ****. **:.*::::: .:* * ****.: *:* :. ******: ***:*: .:*::: : :. : :. * ..** ***.*:* :.::.:**:. : *:.::. * .**::*************.*::* ::: *:* **.:** :: . **:***** ** **..:** ****. * :**:.**:****::*: ** ***:.: :** *:*.*:***:*****::* * *::****: :* :**. * *.. ** .**::**** :::*:: ::*:..* :** .. :* :..:* *: . ", "identical_positions": 455, "similar_positions": 574, "identity": "20.05%" }, { "cls_id": "homologset.agr.MGI:1352681", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P0DN81-1", "uniprot_id": "O13C7_HUMAN", "id": "P0DN81-1", "name": "Olfactory receptor 13C7", "aln": "MVSANQTASVTEFILLG-LSAHPKLEKTFFVLILLMYLVILLGNGVLILMTVSNSHLHMPMYFFLGNLSFLDICYTTSSVPLILDSFLTPRK-TISFSACAVQMFLSFAMGATECVLLSMMAFDRYVAICNPLRYPVVMSKAAYMPKAAGSWVAGSTASMVQTSLAMRLPFCGDNIINHFTCEILAVLKLACADISVNVISMGVTNVIFLGVPVLFISFSYVFIIATILRIPSAEGRKKAFSTCSAHLTVVVIFYGTILFMYGKPKSKDPLGADKQDLADKLISLFYGVVTPMLNPIIYSLRNKDVKAAVRDLIFQKCFA-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9QZ22-1", "uniprot_id": "Q9QZ22_MOUSE", "id": "Q9QZ22-1", "name": "Olfactory receptor", "aln": "MDRSNETAPLSGFILLG-LSAHPKLEKTFFVLILMMYLVILLGNGVLILVSILDSHLHTPMYFFLGNLSFLDICYTTSSVPLILDSFLTPRK-TISFSGCAVQMFLSFAMGATECVLLSMMAFDRYVAICNPLRYPVVMNKAAYVPMAASSWAGGITNSVVQTSLAMRLPFCGDNVINHFTCEILAVLKLACADISINVISMVVANMIFLAVPVLFIFVSYVFILVTILRIPSAEGRKKAFSTCSAHLTVVLVFYGTILFMYGKPKSKDPLGADKQDLADKLISLFYGVVTPMLNPIIYSLRNKDVRAAVRNLVGQKHLTE", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q2PRE9-1", "uniprot_id": "Q2PRE9_DANRE", "id": "Q2PRE9-1", "name": "Olfactory receptor", "aln": "---MDNSTYFTTVILTGYIDIG-DIKYLCFVVLILLFAAIIVANLFIIGIICKEKSLHEPMYVFLCSLCANQLCGSFALFPFVLGNMLRSKTPEVPLTVCHAQIFALYTYGQVEFCNLAMMSYDRYVAICHPLEYHRIMSPARTMTLIALGWSLQIIIFSLSFSVNVQLKLCGN-VLDKVWCDQYMLVKLACSDTTPNNIAGMTGIAVTIGAPLLLILFSYAKILRVCLKFK-GQTAQKSLYTCILHLISLLNFAVGCSFELIQSRFGKLP---MPAVVRVILSLYFLVCPPLFNPIMYGVRLANIKKALKKMICM-----", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0ACD6B7K1-1", "uniprot_id": "A0ACD6B7K1_DANRE", "id": "A0ACD6B7K1-1", "name": "Olfactory receptor", "aln": "---MENGANFTFIRLTGYLNLDFKMKYFLFAVLTVLYLTIICANSFLIGVICLAKILHKPMYMFLCSLFVNELYGSTALFPSLQVNLLLNDN-TISLVYCYLQIFCLCTYAMIDFCTLAVMSFDRYVSICYPLQYNKIMTPFRVGLLIALVWTYCFIQFFIFLSFKFKLQLCGN-VMEKVWCDNYLLVNLACSKSSLHNAYGIYLAVVTAVIPLTLIFYSYTRIIKICLSFS-KEAKKKALSTCTPHIISLLNFTLGCFFETLQSRFDEIR---TPALIRVIVSLYLLMCQPLLNPILYAIRLKNIRLVCKNLVLSKIGIA", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :: : .: . * * :. .:: *.:: ::: .*: .* .:* : . ** ***.** .* :: : : .* : .:* . :.: * *:* : . : *::*::****:** **.* :*. * * : *. .:* :**: ::::. *: :::***:. : : : *: :* **. *: * : : :*:: ** *: :: * * :.: . : ::**: : *::***:*.:* ::: . :.:: ", "identical_positions": 61, "similar_positions": 104, "identity": "19.0%" }, { "cls_id": "homologset.agr.MGI:1352683", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0ABZ3NNQ8-1", "uniprot_id": "A0ABZ3NNQ8_RAT", "id": "A0ABZ3NNQ8-1", "name": "Olfactory receptor", "aln": "MEVSNQ-STVTEFVLLGLSAHP-TLEKTFFVLILLMYLVILLGNGVLILVTILDSHLHTPMYFFLGNLSFLDICYTTSSVPLVLDGFLTPRK-TISFSGCAVQMFLSFAMGATECVLLGMMAFDRYVAICNPLRYPVVMSKAAYVPMAVSSWVAGGANSMVQISLAVQLPFCGDNVINHFICEILAVLKLACADISINVISMGVANVIFLGVPVLFIFVSYIFILSTILRIPSAEGRKKAFSTCSAHLTVVIIFYGTILFMYGKPKSKDPLGADKQDLADKLISLFYGLLTPMLNPIIYSLRNKDVKTAVRDLASHRCLTQ", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8VGA9-1", "uniprot_id": "Q8VGA9_MOUSE", "id": "Q8VGA9-1", "name": "Olfactory receptor", "aln": "MEGANQ-STVAEFVLLGLSDHP-KLEKTFFVLILLMYLVILLGNGVLILVSILDSHLHTPMYFFLGNLSFLDICYTTSSIPLVLDGFLTPRK-TISFSGCAVQMFLSFAMGATECVLLGMMAFDRYVAICNPLRYPVVMNKSAYVPMAVSSWVAGGANSLVQISLAVQLPFCGDNVINHFTCEILAVLKLACADISINVISMGVANVIFLGVPVLFIFVSYIFILSTILRIPSAEGRKKAFSTCSAHLTVVLVFYGTILFMYGKPKSKDPLGADKQDVSDKLISLFYGVLTPMLNPIIYSLRNKDVKAAVRNLVGQKCLIQ", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P0DN81-1", "uniprot_id": "O13C7_HUMAN", "id": "P0DN81-1", "name": "Olfactory receptor 13C7", "aln": "MVSANQTASVTEFILLGLSAHP-KLEKTFFVLILLMYLVILLGNGVLILMTVSNSHLHMPMYFFLGNLSFLDICYTTSSVPLILDSFLTPRK-TISFSACAVQMFLSFAMGATECVLLSMMAFDRYVAICNPLRYPVVMSKAAYMPKAAGSWVAGSTASMVQTSLAMRLPFCGDNIINHFTCEILAVLKLACADISVNVISMGVTNVIFLGVPVLFISFSYVFIIATILRIPSAEGRKKAFSTCSAHLTVVVIFYGTILFMYGKPKSKDPLGADKQDLADKLISLFYGVVTPMLNPIIYSLRNKDVKAAVRDLIFQKCFA-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q2PRE9-1", "uniprot_id": "Q2PRE9_DANRE", "id": "Q2PRE9-1", "name": "Olfactory receptor", "aln": "---MDNSTYFTTVILTGYIDIG-DIKYLCFVVLILLFAAIIVANLFIIGIICKEKSLHEPMYVFLCSLCANQLCGSFALFPFVLGNMLRSKTPEVPLTVCHAQIFALYTYGQVEFCNLAMMSYDRYVAICHPLEYHRIMSPARTMTLIALGWSLQIIIFSLSFSVNVQLKLCGN-VLDKVWCDQYMLVKLACSDTTPNNIAGMTGIAVTIGAPLLLILFSYAKILRVCLKFK-GQTAQKSLYTCILHLISLLNFAVGCSFELIQSRFGKLP---MPAVVRVILSLYFLVCPPLFNPIMYGVRLANIKKALKKMICM-----", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0ACD6B7K1-1", "uniprot_id": "A0ACD6B7K1_DANRE", "id": "A0ACD6B7K1-1", "name": "Olfactory receptor", "aln": "---MENGANFTFIRLTGYLNLDFKMKYFLFAVLTVLYLTIICANSFLIGVICLAKILHKPMYMFLCSLFVNELYGSTALFPSLQVNLLLNDN-TISLVYCYLQIFCLCTYAMIDFCTLAVMSFDRYVSICYPLQYNKIMTPFRVGLLIALVWTYCFIQFFIFLSFKFKLQLCGN-VMEKVWCDNYLLVNLACSKSSLHNAYGIYLAVVTAVIPLTLIFYSYTRIIKICLSFS-KEAKKKALSTCTPHIISLLNFTLGCFFETLQSRFDEIR---TPALIRVIVSLYLLMCQPLLNPILYAIRLKNIRLVCKNLVLSKIGIA", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :: : .: . * * :: *.:: ::: .*: .* .:* : . ** ***.** .* :: : : .* : .:* . :.: * *:* : . : *.:*::****:** **.* :*. . * : *. .:* :**: ::::. *: :::***:. : : .: *: :* ** *: * : : :*:: ** *: :: * * :.: . : ::**: : *::***:*.:* ::: . :.: ", "identical_positions": 60, "similar_positions": 101, "identity": "18.69%" }, { "cls_id": "homologset.agr.MGI:1352684", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9QZ20-1", "uniprot_id": "Q9QZ20_MOUSE", "id": "Q9QZ20-1", "name": "Olfactory receptor", "aln": "MDVSNQT-TVTEFVLLGLSAHPKLEKTFFVLILSMYLVILLGNGVLILVSILDSHLHTPMYFFLGNLSFLDICYTTSSVPLVLDGFLTPRK-TISFSGCAVQMFLSFAMGATECVLLGMMAFDRYVAICNPLRYPVVMNKAAYVPMAVSSWVAGGANSLVQISLAVQLPFCGDNVINHFICEILAVLKLACADISINVISMGVANVIFLGVPVLFIFVSYIFILSTILRIPSAEGRKKAFSTCSAHLTVVIIFYGTILFMYGKPKSKDPLGADKQDLADKLISLFYGLLTPMLNPIIYSLRNKDVKAAVRNLASHRCLTF", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0ABZ3NNQ8-1", "uniprot_id": "A0ABZ3NNQ8_RAT", "id": "A0ABZ3NNQ8-1", "name": "Olfactory receptor", "aln": "MEVSNQS-TVTEFVLLGLSAHPTLEKTFFVLILLMYLVILLGNGVLILVTILDSHLHTPMYFFLGNLSFLDICYTTSSVPLVLDGFLTPRK-TISFSGCAVQMFLSFAMGATECVLLGMMAFDRYVAICNPLRYPVVMSKAAYVPMAVSSWVAGGANSMVQISLAVQLPFCGDNVINHFICEILAVLKLACADISINVISMGVANVIFLGVPVLFIFVSYIFILSTILRIPSAEGRKKAFSTCSAHLTVVIIFYGTILFMYGKPKSKDPLGADKQDLADKLISLFYGLLTPMLNPIIYSLRNKDVKTAVRDLASHRCLTQ", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P0DN81-1", "uniprot_id": "O13C7_HUMAN", "id": "P0DN81-1", "name": "Olfactory receptor 13C7", "aln": "MVSANQTASVTEFILLGLSAHPKLEKTFFVLILLMYLVILLGNGVLILMTVSNSHLHMPMYFFLGNLSFLDICYTTSSVPLILDSFLTPRK-TISFSACAVQMFLSFAMGATECVLLSMMAFDRYVAICNPLRYPVVMSKAAYMPKAAGSWVAGSTASMVQTSLAMRLPFCGDNIINHFTCEILAVLKLACADISVNVISMGVTNVIFLGVPVLFISFSYVFIIATILRIPSAEGRKKAFSTCSAHLTVVVIFYGTILFMYGKPKSKDPLGADKQDLADKLISLFYGVVTPMLNPIIYSLRNKDVKAAVRDLIFQKCFA-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q2PRE9-1", "uniprot_id": "Q2PRE9_DANRE", "id": "Q2PRE9-1", "name": "Olfactory receptor", "aln": "--MDNSTYFTTVILTGYIDIG-DIKYLCFVVLILLFAAIIVANLFIIGIICKEKSLHEPMYVFLCSLCANQLCGSFALFPFVLGNMLRSKTPEVPLTVCHAQIFALYTYGQVEFCNLAMMSYDRYVAICHPLEYHRIMSPARTMTLIALGWSLQIIIFSLSFSVNVQLKLCGN-VLDKVWCDQYMLVKLACSDTTPNNIAGMTGIAVTIGAPLLLILFSYAKILRVCLKFK-GQTAQKSLYTCILHLISLLNFAVGCSFELIQSRFGKLP---MPAVVRVILSLYFLVCPPLFNPIMYGVRLANIKKALKKMICM-----", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0ACD6B7K1-1", "uniprot_id": "A0ACD6B7K1_DANRE", "id": "A0ACD6B7K1-1", "name": "Olfactory receptor", "aln": "--MENGANFTFIRLTGYLNLDFKMKYFLFAVLTVLYLTIICANSFLIGVICLAKILHKPMYMFLCSLFVNELYGSTALFPSLQVNLLLNDN-TISLVYCYLQIFCLCTYAMIDFCTLAVMSFDRYVSICYPLQYNKIMTPFRVGLLIALVWTYCFIQFFIFLSFKFKLQLCGN-VMEKVWCDNYLLVNLACSKSSLHNAYGIYLAVVTAVIPLTLIFYSYTRIIKICLSFS-KEAKKKALSTCTPHIISLLNFTLGCFFETLQSRFDEIR---TPALIRVIVSLYLLMCQPLLNPILYAIRLKNIRLVCKNLVLSKIGIA", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * : . : :. :: *.:: :: .*: .* .:* : . ** ***.** .* :: : : .* : .:* . :.: * *:* : . : *.:*::****:** **.* :*. . * : *. .:* :**: ::::. *: :::***:. : : .: *: :* ** *: * : : :*:: ** *: :: * * :.: . : ::**: : *::***:*.:* ::: . :.: ", "identical_positions": 59, "similar_positions": 99, "identity": "18.44%" }, { "cls_id": "homologset.agr.MGI:1352686", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0ABK0LMM2-1", "uniprot_id": "A0ABK0LMM2_RAT", "id": "A0ABK0LMM2-1", "name": "Olfactory receptor", "aln": "MDRSNETSLVSYFILLGLSAHPRLEKTFFVLILLMYLVILLGNGVLILVTILDSHLHTPMYFFLGNLSFLDICYTTSSIPLVLDGFLTPRKTISFSGCAMQMFLSFAMGATECVLLGMMAFDRYVAICNPLRYPVVMSKAAYVPMAAGSWAGGSITATVQTSLAMRLPFCGDNVINHFTCEILAVLKLACADISINVISMAVGNAVFLGVPVLFIFVSYIFILSTILRIPSAEGRKKAFSTCSAHLTVVIVFYGTILFMYGKPKSKDPLGADKQDLADKLISLFYGVLTPMLNPIIYSLRNKDVRAAVRNLLHQKHFKW", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9QZ19-1", "uniprot_id": "Q9QZ19_MOUSE", "id": "Q9QZ19-1", "name": "Olfactory receptor", "aln": "MERSNKTTPVSSFILLGLSAHPKLEKTFFVLILLMYLVILLGNVVLILVSILDSHLHTPMYFFLGNLSFLDICYTTSSVPLILDSFLTPRKTISFSGCAVQMFLSFAMGATECVLLGMMAFDRYVAICNPLRYPVVMSKAAYVPMAAGSWVSGSITATVQISLAMTLPFCGDNVINHFTCEILAVLKLACADISINVISMAVANAMFLGVPVLFIFVSYIFILSTILRIPSAEGRKKAFSTCSAHLTVVLVFYGTILFMYGKPKSKDPLGADKQDLADKLISLFYGVVTPMLNPIIYSLRNKDVKAAVTNLVGQKHFKW", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P0DN81-1", "uniprot_id": "O13C7_HUMAN", "id": "P0DN81-1", "name": "Olfactory receptor 13C7", "aln": "MVSANQTASVTEFILLGLSAHPKLEKTFFVLILLMYLVILLGNGVLILMTVSNSHLHMPMYFFLGNLSFLDICYTTSSVPLILDSFLTPRKTISFSACAVQMFLSFAMGATECVLLSMMAFDRYVAICNPLRYPVVMSKAAYMPKAAGSWVAGSTASMVQTSLAMRLPFCGDNIINHFTCEILAVLKLACADISVNVISMGVTNVIFLGVPVLFISFSYVFIIATILRIPSAEGRKKAFSTCSAHLTVVVIFYGTILFMYGKPKSKDPLGADKQDLADKLISLFYGVVTPMLNPIIYSLRNKDVKAAVRDLIFQKCFA-", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* :*:*: *: **********:******************** ****::: :**** ********************:**:**.***********.**:****************.*************************:* *****..** :: ** **** *******:********************:*****.* *.:********* .**:**::*************************::************************************:****************:*** :*: ** * ", "identical_positions": 265, "similar_positions": 35, "identity": "83.07%" }, { "cls_id": "homologset.agr.MGI:1352738", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZZX2-1", "uniprot_id": "D3ZZX2_RAT", "id": "D3ZZX2-1", "name": "", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MDANRPG---------------AFVLSSAPLAALHNMA-EMK------TSLFPYAL---QGPAGFKTPALGSLGAQLPLGT------------PHGISDILGR--PVGAAGGGLLG--SLPRLNGLASSAGVYFGPAAAVARGYPKPLAELPGRPPIFWPG----VVQGSPWRD-------PRLAGSAQAGGVLDKDGKKKHSRPTFSGQQIFALEKTFEQTKYLAGPERARLAYSLGMTESQVKVWFQNRRTKWRKRHAAEMASAKKKQDSDAEKLKVGGSDAEDDDEYNRPLDPNSDDEKITRLLKKHKPSNLALVSPCGGSAGDAL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "D3Z4R4-1", "uniprot_id": "D3Z4R4_MOUSE", "id": "D3Z4R4-1", "name": "", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MDANRPG---------------AFVLSSAPLAALHNMA-EMK------TSLFPYAL---QGPAGFKTPALGSLGAQLPLGT------------PHGISDILGR--PVGAAGGGLLG--SLPRLNGLASSAGVYFGPAAAVARGYPKPLAELPGRPPIFWPG----VVQGSPWRD-------PRLAGSAQAGGVLDKDGKKKHSRPTFSGQQIFALEKTFEQTKYLAGPERARLAYSLGMTESQVKVWFQNRRTKWRKRHAAEMASAKKKQDSDAEKLKVGGSDAEDDDEYNRPLDPNSDDEKITRLLKKHKPSNLALVSPCGGSAGDAL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9C056-1", "uniprot_id": "NKX62_HUMAN", "id": "Q9C056-1", "name": "Homeobox protein Nkx-6.2", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MDTNRPG---------------AFVLSSAPLAALHNMA-EMK------TSLFPYAL---QGPAGFKAPALGGLGAQLPLGT------------PHGISDILGR--PVGAAGGGLLG--GLPRLNGLASSAGVYFGPAAAVARGYPKPLAELPGRPPIFWPG----VVQGAPWRD-------PRLAGPAPAGGVLDKDGKKKHSRPTFSGQQIFALEKTFEQTKYLAGPERARLAYSLGMTESQVKVWFQNRRTKWRKRHAVEMASAKKKQDSDAEKLKVGGSDAEDDDEYNRPLDPNSDDEKITRLLKKHKPSNLALVSPCGGGAGDAL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A0R4IY89-1", "uniprot_id": "A0A0R4IY89_DANRE", "id": "A0A0R4IY89-1", "name": "", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MLAVGQMDSNRQS---------------AFVLGSTPLAALHNMT-EMK------TSLFPYAL---QSPAGFKAPSLGNLNSQIPLGT------------PHGISDILGR--PITTAG-QLLS--GFPRINGLATSAGMYFNP-AAVSR-YPKPLTELPGRAPIFWPG----MMQGSPWRD-------PRVPCAAQANMMLDKDGKKKHSRPTFSGQQIFALEKTFEQTKYLAGPERARLAYSLGMTESQVKVWFQNRRTKWRKRHAAEMATAKKKHDSETEKMKES-SDNDEDDEYNKPLDPNSDDEKITRLLKKHKTSNLSLLSPCSNSS-DTL", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A6J3T5M5-1", "uniprot_id": "A0A6J3T5M5_DROME", "id": "A0A6J3T5M5-1", "name": "", "aln": "MLGSPFLSITPAGGSSNPSPTPPPPDAKVAAKQLAQSFQLSANSAFNLALPPAFYRAPPQQHPECLDYGHEAPEMDLINPYMRHHSFAAAAQGSPPSAAQRHHLAAAMSNGFADVHAHAMAAADYQQQLADYHSAAAAAAVYANNNNNNNNNSSNNNNSSPLMLLKAAHGGGLKDSDSPSTTPPPASSRLHSDSSPSPRYEHNSSPGVDSAKSYALSQRSSGAEDPCQTSESASPPPQGQNDYSPENLSSQRAKFQHHHGVNPLALHNANHAGNPGCHNNNNHMDHKLPLSFLGPPLAALHSMTTEMKGQGVGGSSASANGLSYSHSPNSHLISDRGSGGSSSSSSTTTTNTNSQGAPNPHGIDTILSKPPPVTSAGLSALTGAGIPRFSIAAAAAGMAQYLSQSQGAPLKTHAGHIVDRTHLYWPGLQGLVANPIAWRERLSNTMSANLSQSHQHHPSNDKDGKKKHTRPTFSGQQIFALEKTFEQTKYLAGPERAKLAYALGMSESQVKVWFQNRRTKWRKRHAAEMATAKRKQDDMGGDNDGDCSETMDSD--NESLDMGESPAQNKRCRSNSSGSSQQQQDNYRH------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ::*: . .: : ..******.*: *** :* . .* :.* .. . *. .:. . .* ****. **.: *: :** * .:**:. *::**: : . . .: .*. ::*** : : .**: ..:. . ********:****************************:***:***:********************.***:**:*:*. . . . *: :.* *..** ... : .* .: . *. . ", "identical_positions": 113, "similar_positions": 82, "identity": "18.99%" }, { "cls_id": "homologset.agr.MGI:1352744", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "M0RA58-1", "uniprot_id": "M0RA58_RAT", "id": "M0RA58-1", "name": "E3 ubiquitin-protein ligase", "aln": "----MSRPGQGVMVP----------------VNGLGFPPQNVARVVVWEWLNEHSRWRPYTATVCHHIENVLKEDARGSVVLGQVDAQLVPYIIDLQSMHQFRQDTGTMR-----PVRRNFYDPSSAPGKGIVWEWE----NDGGAWTAYDMDICITIQNAYEKQHPWLDLS--SLGFCYLIYFNSMSQMNRQTRRRRRLRRRLDLAYPLTVGSIPKSQSWPVGASSGQ------------------PCSCQQCLLVNSTRAASNAILASQRRKAPIAPAAPPAPP-----------------PPPPPLPPGGPPSALVVRPSATFAGAALWAAPAAGPTEPAPPPGVPPRSPSAPNGAP-----------------------------TPGQNNLSRPGPQRSTSVSARASIPPG-------VPALPVKNLNGTGPVHPALAGMTGILLCAAGLPVCLTRAPKPILHPPPVSKSDVKPVPGVPGVCRKTKKKHLKKSKNPEDVVRRYMQKVKNP----------PDEDCTICMERLVTASGYEGVLRNKSVRPELVG-------RLGRCGHMYHLLCLVAMYSNGNKVGHKDGSLQCPTCKAIYGEKTGTQPPGKMEFHLIPHSLPGFADTQTIRIVYDIPTGIQGPEHPNPGKKFTARGFPRHCYLPNNEKGRKVLRLLITAWERRLIFTIGTSNTTGESDTVVWNEIHHKTEFGSNLTGHGYPDASYLDNVLAELTAQGVSEAMAKA", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q61010-1", "uniprot_id": "DTX1_MOUSE", "id": "Q61010-1", "name": "E3 ubiquitin-protein ligase DTX1", "aln": "----MSRPGQGVMVP----------------VNGLGFPPQNVARVVVWEWLNEHSRWRPYTATVCHHIENVLKEDARGSVVLGQVDAQLVPYIIDLQSMHQFRQDTGTMR-----PVRRNFYDPSSAPGKGIVWEWE----NDGGAWTAYDMDICITIQNAYEKQHPWLDLS--SLGFCYLIYFNSMSQMNRQTRRRRRLRRRLDLAYPLTVGSIPKSQSWPVGASSGQ------------------PCSCQQCLLVNSTRAASNAILASQRRKAPIAPAAPPAPP-----------------PPPPPLPPGGPPGALVVRPSATFAGAALWAAPATGPTEPAPPPGVPPRSPSAPNGAP-----------------------------TPGQNNLSRPGPQRSTSVSARASIPPG-------VPALPVKNLNGTGPVHPALAGMTGILLCAAGLPVCLTRAPKPILHPPPVSKSDVKPVPGVPGVCRKTKKKHLKKSKNPEDVVRRYMQKVKNP----------PDEDCTICMERLVTASGYEGVLRNKSVRPELVG-------RLGRCGHMYHLLCLVAMYSNGN----KDGSLQCPTCKAIYGEKTGTQPPGKMEFHLIPHSLPGFADTQTIRIVYDIPTGIQGPEHPNPGKKFTARGFPRHCYLPNNEKGRKVLRLLITAWERRLIFTIGTSNTTGESDTVVWNEIHHKTEFGSNLTGHGYPDASYLDNVLAELTAQGVSEAMAKA", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q86Y01-1", "uniprot_id": "DTX1_HUMAN", "id": "Q86Y01-1", "name": "E3 ubiquitin-protein ligase DTX1", "aln": "----MSRPGHGGLMP----------------VNGLGFPPQNVARVVVWEWLNEHSRWRPYTATVCHHIENVLKEDARGSVVLGQVDAQLVPYIIDLQSMHQFRQDTGTMR-----PVRRNFYDPSSAPGKGIVWEWE----NDGGAWTAYDMDICITIQNAYEKQHPWLDLS--SLGFCYLIYFNSMSQMNRQTRRRRRLRRRLDLAYPLTVGSIPKSQSWPVGASSGQ------------------PCSCQQCLLVNSTRAASNAILASQRRK------APPAPP-----------------LPPPP-PPGGPPGALAVRPSATFTGAALWAAPAAGPAEPAPPPGAPPRSPGAPGGAR-----------------------------TPGQNNLNRPGPQRTTSVSARASIPPG-------VPALPVKNLNGTGPVHPALAGMTGILLCAAGLPVCLTRAPKPILHPPPVSKSDVKPVPGVPGVCRKTKKKHLKKSKNPEDVVRRYMQKVKNP----------PDEDCTICMERLVTASGYEGVLRHKGVRPELVG-------RLGRCGHMYHLLCLVAMYSNGN----KDGSLQCPTCKAIYGEKTGTQPPGKMEFHLIPHSLPGFPDTQTIRIVYDIPTGIQGPEHPNPGKKFTARGFPRHCYLPNNEKGRKVLRLLITAWERRLIFTIGTSNTTGESDTVVWNEIHHKTEFGSNLTGHGYPDASYLDNVLAELTAQGVSEAAAKA", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q23985-1", "uniprot_id": "DTX_DROME", "id": "Q23985-1", "name": "Protein deltex", "aln": "MASSAGSAASGSVVPGGGGSAASSCATMALSTAGSGGPPVNHAHAVCVWEFESRGKWLPYSPAVSQHLERAHAKKLT-RVMLSDADPSLEQYYVNVRTMTQESEAETAGSGLLTIGVRRMFYAPSSPAGKGTKWEWSGGSADSNNDWRPYNMHVQCIIEDAWARGEQTLDLCNTHIGLPYTINFCNLTQLRQPSGPMRSIRRTQQAPYPLVKLTPQQANQLKSNSASVSSQYNTLPKLGDTKSLHRVPMTRQQHPLPTSHQVQQQQHQHQHQQQQQQQHHHQHQQQQHQQQQQHQMQHHQIHHQTAPRKPPKKHSEISTTNLRQILNNLNIFSSSTKHQSNMSTAASASSSSSSASLHHANHLSHAHFSHAKNMLTASMNSHHSRCSEGSLQSQRSSRMGSHRSRSRTRTSDTDTNSVKSHRRRPSVDTVSTYLSHESKESLRSRNFAISVNDLLDCSLGSDEVFVPSLPPSSLGERAPVPPPLPLHPRQQQQQQQQQQQLQMQQQQQAQQQQQQSIAGSIVGVDPASDMISRFVKVVEPPLWPNAQPCPMCMEELVHSAQNPAISLSRCQHLMHLQCLNGMIIAQQNEMNKNLFIECPVCGIVYGEKVGNQPIGSMSWSIISKNLPGHEGQNTIQIVYDIASGLQTEEHPHPGRAFFAVGFPRICYLPDCPLGRKVLRFLKIAFDRRLLFSIGRSVTTGREDVVIWNSVDHKTQFN------MFPDPTYLQRTMQQLVHLGVTD-----", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . .. * ::* . * * ** * *:.* ::.:.:* **:.:*.:*:*.. :. *:*.:.*..* * :::::* * : : *** ** ***..*** ***. :... * .*:*.: *::*: : . ***. :*: * * * .::*:.: : * :** : .***. : :::. .::* . * : ** * .* :. .: .:::: ..* ** . ... : . ::::.: :: :....... *..*. : .:. .* *.:*: * : :. .. *:: . . : : :* . . : * .* : ** * .: *** : : :::: ::.:: : :: *: :: * .* : ::* .. : .. *** *.** *: ** ** .* : *: ::**.* :****.*.** *.*.: :*.:.***. . :**:*****.:*:* ***:**: * * **** ****: ******:* *::***:*:** * ***..*.*:**.:.***:*. :**.:**:..: :*. **:: ", "identical_positions": 170, "similar_positions": 220, "identity": "22.67%" }, { "cls_id": "homologset.agr.MGI:1352745", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P85845-1", "uniprot_id": "FSCN1_RAT", "id": "P85845-1", "name": "Fascin", "aln": "MTAN----GTAEAVQIQ---------FGLISCGNKYLTAEAFGFKVNASASSLKKKQIWTLEQPPDEAGSAAVCLRSHLGPYLAADKDGNVTCEREVPDGDCRFLVVAHDDG--RWSLQSEAHRRYFGGTEDRLSCFAQSVSPAEKWSVHIAMHPQVNIYSVTRKRYAHLSARPADEIAVDRDVPWGVDSLITLAFQDQ---RYSVQTSDHRFLRHDGRLVARPEPATGFTLEFRSGKVAFRDCEGRYLAPSGPSGTLKAGKATKVGKDELFALEQSCAQVVLQAA-NERNVSTRQGMDLSANQDEETDQETFQLEIDRDTRKCAFRTHTGKYWTLTATGGVQSTASTKNASCYFDIEWC-ERRITLRASNGKFVTAKKNGQLAATVETAGDSELFLMKLINRPIIVFRGEHGFIGCRK-VTGTLDANRSSYDVFQLEFNDG-AYNIKDSTGKYWTVGSDSSVTSSSDTPVDFFLEFCDYNKVALKVG-GRYLKGDHAGVLKACAETIDPATLWEY", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q61553-1", "uniprot_id": "FSCN1_MOUSE", "id": "Q61553-1", "name": "Fascin", "aln": "MTAN----GTAEAVQIQ---------FGLISCGNKYLTAEAFGFKVNASASSLKKKQIWTLEQPPDEAGSAAVCLRSHLGRYLAADKDGNVTCEREVPDGDCRFLVVAHDDG--RWSLQSEAHRRYFGGTEDRLSCFAQSVSPAEKWSVHIAMHPQVNIYSVTRKRYAHLSARPADEIAVDRDVPWGVDSLITLAFQDQ---RYSVQTSDHRFLRHDGRLVARPEPATGFTLEFRSGKVAFRDCEGRYLAPSGPSGTLKAGKATKVGKDELFALEQSCAQVVLQAA-NERNVSTRQGMDLSANQDEETDQETFQLEIDRDTRKCAFRTHTGKYWTLTATGGVQSTASTKNASCYFDIEWC-DRRITLRASNGKFVTAKKNGQLAASVETAGDSELFLMKLINRPIIVFRGEHGFIGCRK-VTGTLDANRSSYDVFQLEFNDG-AYNIKDSTGKYWTVGSDSSVTSSSDTPVDFFLEFCDYNKVALKVG-GRYLKGDHAGVLKACAETIDPASLWEY", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q16658-1", "uniprot_id": "FSCN1_HUMAN", "id": "Q16658-1", "name": "Fascin", "aln": "MTAN----GTAEAVQIQ---------FGLINCGNKYLTAEAFGFKVNASASSLKKKQIWTLEQPPDEAGSAAVCLRSHLGRYLAADKDGNVTCEREVPGPDCRFLIVAHDDG--RWSLQSEAHRRYFGGTEDRLSCFAQTVSPAEKWSVHIAMHPQVNIYSVTRKRYAHLSARPADEIAVDRDVPWGVDSLITLAFQDQ---RYSVQTADHRFLRHDGRLVARPEPATGYTLEFRSGKVAFRDCEGRYLAPSGPSGTLKAGKATKVGKDELFALEQSCAQVVLQAA-NERNVSTRQGMDLSANQDEETDQETFQLEIDRDTKKCAFRTHTGKYWTLTATGGVQSTASSKNASCYFDIEWR-DRRITLRASNGKFVTSKKNGQLAASVETAGDSELFLMKLINRPIIVFRGEHGFIGCRK-VTGTLDANRSSYDVFQLEFNDG-AYNIKDSTGKYWTVGSDSAVTSSGDTPVDFFFEFCDYNKVAIKVG-GRYLKGDHAGVLKASAETVDPASLWEY", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A0A0MPL5-1", "uniprot_id": "A0A0A0MPL5_DANRE", "id": "A0A0A0MPL5-1", "name": "Fascin", "aln": "MSSE----GIGETLVIR---------FGLINADNKYLTAEMFGFKINASASSMKKKQVWTLEQSGDHGDSNAVFIKSHLGRYLASDKDGKVTADSEQPGPDCRFLVIAHDDG--RWSLQSEPHARYLGGTEDRIACFAQSISPAEKWNVHLAVHPQVNVYSIARKRYAHLCAD-RNELAVDRDVPWGVDSLLTLVYLDH---RYHLQTADNRFLSCGGTLTAKPDRDTGFTLEFRAGKVAFRDATGKYIAPTGPTGTMKSGRSARVGKDELFVLEQSHGQVVLTAS-NDRNISMRQGVDLSANQDEESDQEVFQMEMDRESKRCAFRSFNGRYWSLTSSGAIQCSALTKSPSCFFDLEWK-GSKVALKASNGKYLAAKKNGQLAAAVDSAGEQEEFVLKLINRPLIVLRGEHGFIGCRKQGTGTLDSNRSSYDVFQLEYNNN-AYSLRDSVGKYWTVESDGSVISSGAAPVYFHFEFCDFNKVAIKTKEGKYLKGDHAGVLKASAQGIADATLWEY", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q24524-1", "uniprot_id": "SING_DROME", "id": "Q24524-1", "name": "Protein singed", "aln": "MNGQGCELGHSNGDIISQNQQKGWWTIGLINGQHKYMTAETFGFKLNANGASLKKKQLWTLE--PSNTGESIIYLRSHLNKYLSVDQFGNVLCESDERDAGSRFQISISEDGSGRWALKNESRGYFLGGTPDKLVCTAKTPGASEFWTVHLAARPQVNLRSIGRKRFAHLSES-QDEIHVDANIPWGEDTLFTLEFRAEEGGRYALHTCNNKYLNANGKLQVVCNEDCLFSAEYHGGHLALRDRQGQYLSPIGSKAVLKS-RSSSVTRDELFSLEDSLPQASFIAGLNLRYVSVKQGVDVTANQDEVGENETFQLEYDWSAHRWALRTTQDRYWCLSAGGGIQATGNRRCADALFELIWHGDGSLSFRANNGKFLATKRSGHLFATSESIEEIAKFYFYLINRPILVLKCEQGFVGYRTPGNLKLECNKATYETILVERAQKGLVHLKAHSGKYWRIEGESISVDADAPSDGFFLELREPTRICIRSQQGKYLGATKNGAFKLLDDGTDSATQWEF", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*..: * .: * :***. :**:*** ****:**..:*:****:**** .. .. : ::***. **: *: *:* .: : . ..** : :** **:*:.*.: ::*** *:: * *:: ..:* *.**:* :****: *: ***:***. :*: ** ::*** *:*:** : . ** ::*.::::* .* * . : :: *::.*::*:** *:*::* *....:*: ::: * :**** **:* *. : *. * * :* :**:*::***** ::*.**:* * .::: *:*: .:** *:: *.:*.:. : ... *:: * ::::*.***::::*:.*:* *: :: : * : *****::*:: *:**:* *. . .*:.*:::*:.: :* : :: **** : .:. .:. .. *.:*: : .::.:: *:** . : *.:* : *: **:", "identical_positions": 163, "similar_positions": 193, "identity": "31.59%" }, { "cls_id": "homologset.agr.MGI:1352746", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I5ZZP9-1", "uniprot_id": "A0A8I5ZZP9_RAT", "id": "A0A8I5ZZP9-1", "name": "", "aln": "MQFPMGPACIFLRKGIAEKQRERPLGQDEIDELREAFLEFDKDRDGFISYKDLGNLMRTMGYMPTEMELTELGQQIRMNLGGRVDFEDFVELMTPKLLAETAGMIGVQEMRDAFKEFDANGDGEITLAELQQAMQRLLGEKLTPREIAEVVQEADINGDGTVDFEGNTGQKSRILHLS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9JLK3-1", "uniprot_id": "CABP5_MOUSE", "id": "Q9JLK3-1", "name": "Calcium-binding protein 5", "aln": "MQFPMGPACIFLRKGIAEKQRERPLGQDELDELREAFLEFDKDQDGFISYKDLGNLMRTMGYMPTEMELTELGQQIRMNLGGRVDFEDFVELMTPKLLAETAGMIGVQEMRDAFKEFDANGDGEITLAELQQAMQRLLGEKLTPREIAEVVQEADINGDGTVDFEEFVKMMSR-----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9NP86-1", "uniprot_id": "CABP5_HUMAN", "id": "Q9NP86-1", "name": "Calcium-binding protein 5", "aln": "MQFPMGPACIFLRKGIAEKQRERPLGQDEIEELREAFLEFDKDRDGFISCKDLGNLMRTMGYMPTEMELIELGQQIRMNLGGRVDFDDFVELMTPKLLAETAGMIGVQEMRDAFKEFDTNGDGEITLVELQQAMQRLLGERLTPREISEVVREADVNGDGTVDFEEFVKMMSR-----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "E7FEW4-1", "uniprot_id": "E7FEW4_DANRE", "id": "E7FEW4-1", "name": "", "aln": "-----MTACIFLRG----AKIDRELADDEIEELREAFNEFDKDKDGLISCKDLGNLMRTMGYMPTEMELIELGQNINMNLGGRVDFEDFVELMTPKLLAETAGMIGVKELRDAFKEFDMDGDGAITTEELRCAMTKLLGEHMNRREIDAVVREADNNGDGTVDFEEFVKMLSSV----", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .****** : :* *.:**::****** *****:**:** ******************* ****:*.*********:********************:*:******** :*** ** **: ** :****::. *** **:*** ********* . * ", "identical_positions": 118, "similar_positions": 22, "identity": "66.29%" }, { "cls_id": "homologset.agr.MGI:1352747", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9ERQ6-1", "uniprot_id": "CSPG5_RAT", "id": "Q9ERQ6-1", "name": "Chondroitin sulfate proteoglycan 5", "aln": "-----MGRAGGGGPGWGPPPVLLLLGVTLVLTAGAVPAREAGSAIEAEELVRSGLAWESRANDTREEAGLPAAGEDETSWTERGSELAAVGPGVGPEETLEASAAVTGTAWLEADGTGLGGVTAEAGSGDAQTLPATLQAPDEALGSSTMPPAIPEATEASGPPSPTLRDKPSLVPELPKEIPLEVWLNLGGSTPDPQRPEPTFPLQGTLETQPASDIIDIDYFEGLDSEGRGTDMGRFPGSPGTSENHPDTEGETPSWSLLDLYDDFTPFDESDFYPTTSFYDDLEEEEEEEED-KDAVGGGDLEDESDLLLPSQKPGVGPGTGQPTSRWHAVPPQHTLGMVPGGSISLRPRPGDPGKDLATSENGTECRVGFVRHNGSCRSVCDLFPSYCHNGGQCYLVENIGAFCRCNTQDYIWHKGMRCESIITDFQVMCVAVGSAALVLLLLFMMTVFFAKKLYLLKTENTKLRRTN-KFRTPSELHNDNFSLSTIAEGSHPNVRKLCDTPCVSSPHARALAHCDNIVCQ-------------------DDPSAPHKIQEALKSRL-KEEESFNIQNSMSPKLEGGKGDQDDLEVN-----------------------CLQNNLT------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q71M36-1", "uniprot_id": "CSPG5_MOUSE", "id": "Q71M36-1", "name": "Chondroitin sulfate proteoglycan 5", "aln": "-----MGRAGGGGPDWGPPPVLLLLGVTLVLTAGAVPARETGSAIEAEELVRSSLAWESRANDTREEAGLPAAGEDETSWTERGSEMAAVGPGVGPEEALEASAAVTGTAWLEADGPGLGGVTAEAGSGDAQTLPATLQAPDEALGSSTMPPAIPEATETSGPPSPAVHDKPSVGPELPKEIPLEVRLNLGGSTP-----EPTFPLQGTLETQPASDIIDIDYFEGLDSEGRGADMGSFPGSPGTSENHPDTEGETPSWSLLDLYDDFTPFDESDFYPTTSFYDDLEEEEEEEED-KDTVGGGDLEDENDLLLPSQKPGVGPGTGQPTNRWHAVPPQHTLGMVPGSSISLRPRPGDPGKDLASGENGTECRVGFVRHNGSCRSVCDLFPSYCHNGGQCYLVENIGAFCRCNTQDYIWHKGMRCESIITDFQVMCVAVGSAALVLLLLFMMTVFFAKKLYLLKTENTKLRRTN-KFRTPSELHNDNFSLSTIAEGSHPNVRKFCDTPRVSSPHARALAHYDNIVCQ-------------------DDPSAPHKIQDPLKSRL-KEEESFNIQNSMSPKLEGGKGDQDDLGVN-----------------------CLQNNLT------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O95196-1", "uniprot_id": "CSPG5_HUMAN", "id": "O95196-1", "name": "Chondroitin sulfate proteoglycan 5", "aln": "-----MGRAGGGGPGRGPPPLLLFLGAALVLASGAVPAREAGSAVEAEELVKGSPAWEPPANDTREEAGPPAAGEDEASWTAPGGELA------GPEEVLQESAAVTGTAWLEADSPGLGGVTAEAGSGDAQALPATLQAPHEVLGQSIMPPAIPEATEASGPPSPTPGDKLSPASELPKESPLEVWLNLGGSTPDPQGPELTYPFQGTLEPQPASDIIDIDYFEGLDGEGRGADLGSFPGSPGTSENHPDTEGETPSWSLLDLYDDFTPFDESDFYPTTSFYDDLDEEEEEEEDDKDAVGGGDLEDENELLVPTGKPGLGPGTGQPTSRWHAVPPQHTLGSVPGSSIALRPRPGEPGRDLASSENGTECRSGFVRHNGSCRSVCDLFPSYCHNGGQCYLVENIGAFCRCNTQDYIWHKGMRCESIITDFQVMCVAVGSAALVLLLLFMMTVFFAKKLYLLKTENTKLRRTN-KFRTPSELHNDNFSLSTIAEGSHPNVRKLCNTPRTSSPHARALAHYDNVICQ-------------------DDPSAPHKIQEVLKSCL-KEEESFNIQNSMSPKLEGGKGDQADLDVN-----------------------CLQNNLT------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M3B1Y9-1", "uniprot_id": "A0A8M3B1Y9_DANRE", "id": "A0A8M3B1Y9-1", "name": "", "aln": "MNRKEMRLCSRCWSMPMLSVLLLVCLTPLFAHGNSVVANETEADSAVNVTSLSTEGEEEKIEDVSQFTSLSSSSDLTHTGRKLRDEDVGSGMLEEVITPTPGTPTPSEAATTTLAGPEISLNSAENDHLIPFMEEEEQNVEENVKEVVPTQPPWQDAKGDMETTVFDLDHETSPATPSP-------------------------------THPPSTPDVTVDFFD------IDSHRKNLDPPSQSPHELQGRD--STSWAMPDNYDYMTPYDD-SVSPTTEDYPSSTTSEFETYDDEISTTPPPKRD---PPRLPSKP------------------SFTFPKGATGEEDRRAPPGP-----VDTVNGSDCRLGSVRINGTCKSQCDLKPNYCFNGGQCYVMEGTQMFCRCNIQDYMWHKGARCESVITEFQVMVIAIGASSLMVLLLFMIIVCFAKKLHVLKTENNKLRKRSSKYRPSSEHHNDNFSLSTIAEGSHPNVRKLCDTP-PNLPHARALAYYDNIICQKTMSRYTWECKTKEEPDCEDDPNAQNKLEDPVKAPPPKEDESLNIQNSLTPKHENHKVLGEENSSE---------------------VNSLQNNMM------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0AC58HYG8-1", "uniprot_id": "A0AC58HYG8_DANRE", "id": "A0AC58HYG8-1", "name": "", "aln": "MMNSRRTLFSAGWESMVLSSVLLLHIIALCVNGSSFISNSTGTNSSD------LNGVEVKPAFTGENTPIARAH--VHS-RKPRAGDE-SGSGGETSTSAVTEITVDTSEREHLVGLTIGGIAARLPTLAESQKRALFQLDFNEEGMQDSAPHWKSNRLQADGTLLDP--VTSPPSES--------------------------------SHSKPEEIITVNFHS------PSPQLEIVHDPPGLAQELQGGD--PTSWT--DFYDYLSP----DYSPT------------EVYLEESQPTPPDMEDENVPFIASAVP------------------SNTGVVDYSGSGE--SLPGA-----ANVLGNSGCLLGFVRRNGTCVSPCDIFTGYCFNGGRCYVVDGIGAFCRCNIQEYIWNKGSRCESVISDFQVMCIAVGGAAIMLLLLFMVIVFFSKRLHVLKTENRRLRKHS-KYRPKSEQHIDNFSLSTVAEGSQANVRKLCDTP-TNLPHARALAYYDNIVCQKTMSRYTWEYKPKEDPCSEDD----TSKEEPCKCPP-KEDESLNNQNSVTPKLENDKPATEDNAEEGGVTIDLELLLPKEAKMVPETSPPLHYNVFLYKLPKSPKKSPVLRRPPGRSVQGRPLSQLCPRRSSEPGYSPISTRSLPGVLSGSSSPRLGTAYTP", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . . :**. .* ..:. :..: : . * . : : . : : : : . :. :*. : : * . . * . . : :::.. ... . .. ..: . : ..**: * ** ::* . ** * : .* . * . * .. . ** . ..: * * ** **:* * **: ..**.***:**:::. ***** *:*:*:** ****:*::**** :*:*.:::::*****: * *:*:*::***** :**: . *:*. ** * *******:****:.****:*:** . *******: **::** ** . :: *. **:**:* ***::** *. * : : *: *: ", "identical_positions": 126, "similar_positions": 124, "identity": "18.34%" }, { "cls_id": "homologset.agr.MGI:1352748", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P56163-1", "uniprot_id": "DPF1_RAT", "id": "P56163-1", "name": "Zinc finger protein neuro-d4", "aln": "--------------------------MATVIPSPL-----------SLGEDFYREAIEHCRSYNARLCAERSLRLPFLDSQTGVAQNNCYIWMEKTHRGPGLAPGQIYTYPARCWRKKRRLNILEDPRLRPCEYKIDCEAPLKKEGGLPEGPVLEALLCAETGEKKVELKEEETIMDCQKQQLLEFPHDLEVEDLEEDIPRRKNRAKGKAYGIGGLRKRQDNASLEDRDKPYVCDICGKRYKNRPGLSYHYTHTHLAEEEGEEHTERHALPFHRKNNHKQFYKELAWVPEAQRKHTAKKAPDGTVIPNGYCDFCLGGSKKTGCPEDLISCADCGRSGHPSCLQFTVNMTAAVRTYRWQCIECKSCSLCGTSENDGASW------------------------------------AGLTPQDQLLFCDDCDRGYHMYCLSPPMAEPPEGSWSCHLCLRHLKEKASAYITLT", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9QX66-1", "uniprot_id": "DPF1_MOUSE", "id": "Q9QX66-1", "name": "Zinc finger protein neuro-d4", "aln": "--------------------------MATVIPSPL-----------SLGEDFYREAIEHCRSYNARLCAERSLRLPFLDSQTGVAQNNCYIWMEKTHRGPGLAPGQIYTYPARCWRKKRRLNILEDPRLRPCEYKIDCEAPLKKEGGLPEGPVLEALLCAETGEKKVELKEEETIMDCQKQQLLEFPHDLEVEDLEEDIPRRKNRARGKAYGIGGLRKRQDTASLEDRDKPYVCDICGKRYKNRPGLSYHYTHTHLAEEEGEEHTERHALPFHRKNNHKQFYKELAWVPEAQRKHTAKKAPDGTVIPNGYCDFCLGGSKKTGCPEDLISCADCGRSGHPSCLQFTVNMTAAVRTYRWQCIECKSCSLCGTSEND----------------------------------------------DQLLFCDDCDRGYHMYCLSPPMAEPPEGSWSCHLCLRHLKEKASAYITLT", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q92782-2", "uniprot_id": "DPF1_HUMAN", "id": "Q92782-2", "name": "Zinc finger protein neuro-d4", "aln": "--------------------------MATVIPGPL-----------SLGEDFYREAIEHCRSYNARLCAERSLRLPFLDSQTGVAQNNCYIWMEKTHRGPGLAPGQIYTYPARCWRKKRRLNILEDPRLRPCEYKIDCEAPLKKEGGLPEGPVLEALLCAETGEKKIELKEEETIMDCQKQQLLEFPHDLEVEDLEDDIPRRKNRAKGKAYGIGGLRKRQDTASLEDRDKPYVCDICGKRYKNRPGLSYHYTHTHLAEEEGEENAERHALPFHRKNNHKQFYKELAWVPEAQRKHTAKKAPDGTVIPNGYCDFCLGGSKKTGCPEDLISCADCGRSGHPSCLQFTVNMTAAVRTYRWQCIECKSCSLCGTSEND----------------------------------------------DQLLFCDDCDRGYHMYCLSPPMAEPPEGSWSCHLCLRHLKEKASAYITLT", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AC58HB97-1", "uniprot_id": "A0AC58HB97_DANRE", "id": "A0AC58HB97-1", "name": "", "aln": "MKLKLLLYYMYNTGDLQSYIVSFYIKMATVVQNPLKSQSSGTVIKNSLGEEFYREAIEHCRSYNARLCAERSMRLPFLDSQTGVAQSNCYIWMEKTHRGPGVAPGQLYTYPARCWRKKRRLNILEDPRLGPIEFKIDYEAALKKEGGVPDGPVLESLLSGELLDKKVETKEEEPMSECQKLLMGEFPHELDMEEMEEDVPKRKNRTKGRACGIGGMRKRQDPASLEDRDKPYVCDICGKRYKNRPGLSYHYTHTHLADEEGEEDSERHTLPFQRKNNHK-----------------PKKAADGSVIPNGYCDFCLGGSKKTGCPEDLISCADCGRSGHPSCLQFTVNMTAAVRTYRWQCIECKSCSLCGTSENDVSQLNEAMLFLSVHCVCVVLCFWMPSPQHWCLGTCSYKIQLALFLQDQLLFCDDCDRGYHMYCLSPPMSEPPEGSWSCHLCLRQLKEKASAYITLT", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ****: .** ****:*********************:*************.**************:****:********************** * *:*** **.******:*:*****:**..* :**:* ****.: :*** : ****:*::*::*:*:*:****::*:* ****:***** ***********************************:*****.:***:***:****** .***.**:********************************************************************** **********************:**************:************", "identical_positions": 315, "similar_positions": 42, "identity": "67.02%" }, { "cls_id": "homologset.agr.MGI:1352749", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9NPB3-1", "uniprot_id": "CABP2_HUMAN", "id": "Q9NPB3-1", "name": "Calcium-binding protein 2", "aln": "-------------MGN----------------CAKRPWRRGPKDPLQWLGSPPRGSCPSPSSSPKEQGDP--------------APGVQGYSVLNSLVGPACIFLRPSIAATQLDRELRPEEIEELQVAFQEFDRDRDGYIGCRELGACMRTLGYMPTEMELIEISQQISGGKVDFEDFVELMGPKLLAETADMIGVRELRDAFREFDTNGDGRISVGELRAALKALLGERLSQREVDEILQDVDLNGDGLVDFEEFVRMMSR", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9JLK4-1", "uniprot_id": "CABP2_MOUSE", "id": "Q9JLK4-1", "name": "Calcium-binding protein 2", "aln": "-------------MGN----------------CAKTPWHRGSKERWQWPGSPLGGSRPSPGPRTEEQ------------------EGTQGYSVLGSLVGPACIFLRPSIAATQLDRELRPEEIEELQIAFQEFDRDRDGYIGYRELGACMRTLGYMPTEMELIEISQQISGGKVDFEDFVELMGPKLLAETADMIGVRELRDAFREFDTNGDGCISVGELRAALKALLGERLSQREVDEILQDIDLNGDGLVDFEEFVRMMSR", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0ABK0L206-1", "uniprot_id": "A0ABK0L206_RAT", "id": "A0ABK0L206-1", "name": "", "aln": "--------MVQRPMGN----------------CAKRPWHRGSK-----------------------------------------------------------------------NRELRPEEIEELQVAFQEFDRDRDGYIGYRELGACMRTLGYMPTEMELIEISQQISGGKVDFEDFVELMGPKLLAETADMIGVRELRDAFREFDTNGDGCISVGELRAALKALLGERLSQREVDEILQDIDLNGDGLVDFEEFVRMMSR", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0A0R4IU57-1", "uniprot_id": "A0A0R4IU57_DANRE", "id": "A0A0R4IU57-1", "name": "", "aln": "------------MMGTK---------------PSKRGSMKKGVPPLEGSGLPLAQAMLGGSGDAAAEDDEDEELREGKQFEEPICALVQNCTMLHNIVGPACIFLRQSFVQAQLDRDLRPEEIEELKEAFREFDKDKDGFISCKDLGECMRTMGYMPTEMELIELSQQICGGRVDFEDFVDLMGPKMLAETADMIGVKELRDAFREFDSNGDGQISLAELREAMKKLMGEQLNHREIDEILRDVDLNGDGLVDFEEFVRMMSR", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8M9QL43-1", "uniprot_id": "A0A8M9QL43_DANRE", "id": "A0A8M9QL43-1", "name": "", "aln": "MFMIIREGSAPGAGGTGGMSAPPERTAKQVQAAIKKKVEKQRRQSETGLSEAFNSNTRPKMAQKKKQPVQPPRKAGDGEDEEEEVEPVEAEETEEPKEKEDSDLGPIVESVFGPDRELRPEEIEELREAFKEFDRNK-GYINCRDLGECMRTMGYMPTEMELIELSQTITGGKIDFEDFVELMGPKMLAETADMIGVKELRDAFKEFDSNGDGQISVTELREAMKKLMGEQLNSRDIDDILRDADLNGDGLVDFEEFVRMMSR", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *. * : :*:*********: **:***::: *:*. ::** ****:***********:** * **::******:*****:**********:******:***:**** **: *** *:* *:**:*. *::*:**:* *******************", "identical_positions": 110, "similar_positions": 31, "identity": "41.83%" }, { "cls_id": "homologset.agr.MGI:1352750", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9NZU7-4", "uniprot_id": "CABP1_HUMAN", "id": "Q9NZU7-4", "name": "Calcium-binding protein 1", "aln": "-----MGGGDGAAFKRPGDGARLQRVLGLGSRREPRSLPAGGPAPRRTAPPPPGHASAGPAAMSSHIAKSESKTSLLKAAAAAASGGSRAPRHGPARDPGLPSRRLPGSCPATPQSS---GDPSSRRPLCRPAPREEGARGSQRVLPQAHCRPREALPAAASRPSPSSPLPPARGRDGEERGLSPALGLRGSLRARGRGDSVPAAASEADPFLHR-LRPMLSSAFGQDRSLRPEEIEELREAFREFDKDKDGYINCRDLGNCMRTMGYMPTEMELIELSQQINMNLGGHVDFDDFVELMGPKLLAETADMIGVKELRDAFREFDTNGDGEISTSELREAMRKLLGHQVGHRDIEEIIRDVDLNGDGRVDFEEFVRMMSR-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "O88751-1", "uniprot_id": "CABP1_RAT", "id": "O88751-1", "name": "Calcium-binding protein 1", "aln": "--------------------------------------------------------------MSSHIAKSESKTSLLK--AAAASGGSRAPRHSSARDPGLRGRRLPGPCPDSPATC---GDPSSRRPLCRPVPRDEGARGSRRGLPQAHCRPRETLP-------------PARGRDGEERGLAPALSLRGSLRSRGRGDPAPAGTPEADPFLHQ-LRPMLSSAFGQDRSLRPEEIEELREAFREFDKDKDGYINCRDLGNCMRTMGYMPTEMELIELSQQINMNLGGHVDFDDFVELMGPKLLAETADMIGVKELRDAFREFDTNGDGEISTSELREAMRKLLGHQVGHRDIEEIIRDVDLNGDGRVDFEEFVRMMSR-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9JLK7-1", "uniprot_id": "CABP1_MOUSE", "id": "Q9JLK7-1", "name": "Calcium-binding protein 1", "aln": "----------------------------------------------------------------------------------------------------------MGNCVKSP-----------LRNLSRKMRQEE--KTSYMAVQTS------------------------------EDGLADGGELHGPLMMLAQN--CAVMHNLLGPACIF-LRKGFAENRQPDRSLRPEEIEELREAFREFDKDKDGYINCRDLGNCMRTMGYMPTEMELIELSQQINMNLGGHVDFDDFVELMGPKLLAETADMIGVKELRDAFREFDTNGDGEISTSELREAMRKLLGHQVGHRDIEEIIRDVDLNGDGRVDFEEFVRMMSR-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A2R8PX62-1", "uniprot_id": "A0A2R8PX62_DANRE", "id": "A0A2R8PX62-1", "name": "", "aln": "MSFTLPKSESTTSLLRSSAPARSAVQPPDHRRPQHQRSAAASGAEPADCDASSRRPLCHPSLVGTRNSAEKSHPQPSHGHALSAARSQEDLSELPGGEERKTTRRHHHHHHHHHHHHNRHHHHHRHRSTRDDLPQEPRPKHSHAARMPSRTQSFSESRDETSLFFESPPPARPGSSTSREVGPASTASSSPVPASSSRSSRRSARSSAASSEADFNLRPFLSSVFGQNRELRPEEIDELRDAFKEFDKDKDGFISCKDLGNCMRTMGYMPTEMELIELSQQINMNLGGHVDFEDFVELMGPKLLAETADMIGIKELRNAFKEFDTNGDGEISTGELREAMRKLLGQQVGHRDLEDILRDIDLNGDGRVDFEEFVRMVSR-", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A1Z777-1", "uniprot_id": "A1Z777_DROME", "id": "A1Z777-1", "name": "EF-hand domain-containing protein", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSGSLTEAQIEEIREAFSLYDKERSGWVSVQQLGGVMRALGESLTEAEIYDLANESNADFGGQVQFKDFLYVMSKRLEEQNS----LVCLKQAFKIFDRSEVNSFTINEIRMVMTN-LGEKMSEEDLRELFQDIDQDKDGKISFNEFVTAMRS-", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VBM1-1", "uniprot_id": "Q9VBM1_DROME", "id": "Q9VBM1-1", "name": "EF-hand domain-containing protein", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MDDFDFSSPPPEVRTVHTHTLNDEQLKDCEAAFALFDDDNAKVIPIKLLRDCLRAVAHNPPENEIQDYITEIDTDGSGELYLSDFLYIMSKRYENLTVED----EVILAFKVFDKDGSGFIHENEFRQIMTE-YGDEMEEDEIEEMIRDADANTELKIDYVRFVTMMMET", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * ::.: . ** :*.:. : : * . :*::. .* *: : : : : .*.: :.**: :*. : . : **: ** . . : .*:* * : *.:: . ::.::::* * : : ::.: .** : ", "identical_positions": 24, "similar_positions": 59, "identity": "6.32%" }, { "cls_id": "homologset.agr.MGI:1352751", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9JHE8-1", "uniprot_id": "NINJ2_RAT", "id": "Q9JHE8-1", "name": "Ninjurin-2", "aln": "MESDREIIHLQHRHSTPGGNQRHINLNHYATKKSVAESMLDVALFMSNAMRLKSVLEQGPFSQYYTTLLTLISASLLLQVVIGILLVVIARLNLNEVENQWRLNQLNNAATTLVFITVVINIFITAFGAHKTGSVAARTSSNPI--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9JL89-1", "uniprot_id": "NINJ2_MOUSE", "id": "Q9JL89-1", "name": "Ninjurin-2", "aln": "MESDRETIHLQHRHSMRGGNQR-IDLNFYATKKSVAESMLDVALFMSNAMRLKSVLQQGPFAEYYTTLVTLIIVSLLLQVVISLLLVFIAILNLNEVENQRHLNKLNNAATILVFITVVINIFITAFGAHHAASMAARTSSNPI--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9NZG7-1", "uniprot_id": "NINJ2_HUMAN", "id": "Q9NZG7-1", "name": "Ninjurin-2", "aln": "MESARENIDLQPGSSDPR-SQP-INLNHYATKKSVAESMLDVALFMSNAMRLKAVLEQGPSSHYYTTLVTLISLSLLLQVVIGVLLVVIARLNLNEVEKQWRLNQLNNAATILVFFTVVINVFITAFGAHKTGFLAARASRNPL--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "E7FE82-1", "uniprot_id": "E7FE82_DANRE", "id": "E7FE82-1", "name": "", "aln": "MPAATGRTDPQP-------TEP-LNMNHYATKKSVAESMLDVALLMANASQLKAVLEQGPEFRYYLTVIILIGASLFFQVLAGALFVNMARKNLNNVANQRKLDIMNNVATGLVFLTVIINIFITAFGVQKTGLYPKQ--------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A8JQY7-1", "uniprot_id": "A8JQY7_DROME", "id": "A8JQY7-1", "name": "", "aln": "MASGLQRVNENE--------MKAMDANRYATKKTIAQGMLDIALLTANASQLKYILQVGEQHQFYKLMLILISLSIVMQLLVGILFVVIGSLNINRQQDQTAAVILNDVILVVVFIISVVNVIISGFGIEYSSQPLRLLDQHEKTP", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* : . : :: * *****::*:.***:**: :** :** :*: * .:* :: ** *:.:*:: . *:* :. *:*. .* :*:. :**: ::*::*:.** . :. ", "identical_positions": 36, "similar_positions": 45, "identity": "24.66%" }, { "cls_id": "homologset.agr.MGI:1352752", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9QXQ1-1", "uniprot_id": "PDE7B_MOUSE", "id": "Q9QXQ1-1", "name": "3',5'-cyclic-AMP phosphodiesterase 7B", "aln": "------------------------------------------------------------------MSCLMVERCGEVLFESP----EQSVKCVCMLGDVRLRGQTGVPAER---RGSYPFIDFRLLNNTTHSGEIGTKK-----------------KVKRLLSFQRYFHASRLLRGIIPQAPLHLLDEDYLGQARHMLSKVGTWDFDIFLFDRLTNG--NSLVTLLCHLFNSHGLIHHFKLDMVT--LHRFLVMVQEDYHGHNPYHNAVHAADVTQAMHCYLKEPKLASFLTPLDIMLGLLAAAAHDVDHPGVNQPFLIKTNHHLANLYQNMSVLENHHWRSTIGMLRESRLLAHLPKEMTQDIEQQLGSLILATDINRQNEFLTRLKAHLHNKDLRLENVQDRHFMLQIALKCADICNPCRIWEMSKQWSERVCEEFYRQGDLEQKFELEISPLCNQQKDS-----IPSIQIGFMTYIVEPLFREWARFTGNSTLSENMLSHLAHNKAQWKSLLSNQHRRRGSG-----QDLAGPAPETLEQTEGATP", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8I6AIQ8-1", "uniprot_id": "A0A8I6AIQ8_RAT", "id": "A0A8I6AIQ8-1", "name": "Phosphodiesterase", "aln": "------------------MPVLERYFHSAELGRRWTAPEAVLPSSLGSRPGCQQGPLPWDLPEMIRMVKLVWKSKSELQATKPRGILENEDAFHGFPGDVRLRGQTGVPAER---RGSYPFIDFRLLNNTTHSGEIGSKK-----------------KVRRLLSFQRHFHESRLLRGMTPQAPLHLLDEDYLGQARHMLSKVGMWDFDIFLFDRLTNG--NSLVTLLCHLFNSHGLIHHFKLDMVT--LHRFLVMVQEDYHGHNPYHNAVHAADVTQAMHCYLKEPKLASFLTPLDIMLGLLAAAAHDVDHPGVNQPFLIKTNHHLANLYQNMSVLENHHWRSTIGMLRESRLLAHLPKEMTQDIEQQLGSLILATDINRQNEFLTRLKAHLHNKDLRLENIQDRHFMLQIALKCADICNPCRIWEMSKQWSERVCEEFYRQGDLEQKFELEISPLCNQQKDS-----IPSIQIGFMTYIVEPLFREWARFTGNSTLSESMLNHLAHNKAQWKSLLSNQHRRRGSG-----QDPAGTAPETLEQTEGATP", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9NP56-1", "uniprot_id": "PDE7B_HUMAN", "id": "Q9NP56-1", "name": "3',5'-cyclic-AMP phosphodiesterase 7B", "aln": "------------------------------------------------------------------MSCLMVERCGEILFENP----DQNAKCVCMLGDIRLRGQTGVRAER---RGSYPFIDFRLLNSTTYSGEIGTKK-----------------KVKRLLSFQRYFHASRLLRGIIPQAPLHLLDEDYLGQARHMLSKVGMWDFDIFLFDRLTNG--NSLVTLLCHLFNTHGLIHHFKLDMVT--LHRFLVMVQEDYHSQNPYHNAVHAADVTQAMHCYLKEPKLASFLTPLDIMLGLLAAAAHDVDHPGVNQPFLIKTNHHLANLYQNMSVLENHHWRSTIGMLRESRLLAHLPKEMTQDIEQQLGSLILATDINRQNEFLTRLKAHLHNKDLRLEDAQDRHFMLQIALKCADICNPCRIWEMSKQWSERVCEEFYRQGELEQKFELEISPLCNQQKDS-----IPSIQIGFMSYIVEPLFREWAHFTGNSTLSENMLGHLAHNKAQWKSLLPRQHRSRGSSGSGPDHDHAGQGTESEEQ-EGDSP", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P06776-1", "uniprot_id": "PDE2_YEAST", "id": "P06776-1", "name": "3',5'-cyclic-nucleotide phosphodiesterase 2", "aln": "MSTLFLIGIHEIEKSQTIVQNEHYFDRVIELQDLDSLMVALYKDRVSPFPNVHNFETGVSIVLYDPSKFQLSVRQLDVLFKRFFP--SFNISAIDHTREENLQRLECVERENSICRNRITRINHWMYHHHDDTPDGINKNSYGTVNGNSVPTQACEANIYTLLLHLNDSKAQHLRKASVPRLIRNIEFMSFLSDPIEKISQEGSHYWNILSTWDFCALSLSTQELIWCGFTLIKKLSKDAKVLIADNKLLLLLFTLESSYHQVNKFHNFRHAIDVMQATWRLCTYLLKD---NPVQTLLLCMAAIGHDVGHPGTNNQLLCNCESEVAQNFKNVSILENFHRELFQQLLSEHWPQLLS---ISKKKFDFISEAILATDMALHSQYEDRLMH---------ENPMKQITLISLIIKAADISNVTRTLSISARWAYLITLEFN-DCALLETFHKAHRPEQDCFGDSYKNVDSPKEDLESIQNILVNVTDPDDIIKDHPHIPNGQIFFINTFAEVFFNALSQKFSGLKFLS-----DNVKINKEYWMKHKKPQ-", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : :: . . : .*: * *. *. . *:. : : : : .*: :: ** . . : .:* :. *: :: .:*.:. . :*: * ::*: : .: : * : : * :. *: :. * :*. ::..** * :** ** ** ** . .*:: :* :** .***.***.*: :* : : .:*: ::*:*:***.* . :* * :::. : :.. *****: :.:: ** *: .: ::.: :*.***.* * .:* :*: : ** : * :.*. * : ** *. :: : *: : :..:. :.:. : .: : . *..:. * . * : : ", "identical_positions": 79, "similar_positions": 143, "identity": "14.36%" }, { "cls_id": "homologset.agr.MGI:1352753", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P43219-1", "uniprot_id": "GIPR_RAT", "id": "P43219-1", "name": "Gastric inhibitory polypeptide receptor", "aln": "---MPLRLLLLLLWLWGLSLQRAETDSEGQ-TTGELYQRWERYGWECQNTLEATEPPSGLACNGSFDMYACWNYTAANTTARVSCPWYLPWYRQVAAGFVFRQCGSDGQWG------SWRDHTQCENPEKNGAFQD-QKLILERLQVVYTVGYSLSLATLLLALLILSLFRRLHCTRNYIHMNLFTSFMLRAGAILTRDQLLPPLGPYTG---NQTPTLWNQALAACRTAQILTQYCVGANYTWLLVEGVYLHHLLVVVRRSEKGHFRCYLLLGWGAPALFVIPWVIVRYLYENTQCWERNEVKAIWWIIRTPILITILINFLIFIRILGILVSKLRTRQMRCPDYRLRLARSTLTLMPLLGVHEVVFAPVTEEQAEGSLRFAKLAFEIFLSSFQGFLVSVLYCFINKEVQSEIR------RLRLSLQEQCPRPHLGQAPR--------------AVPLSSAP----------------------------QEAAIRNALPSGMLHVPGDEV----LESYC", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q0P543-1", "uniprot_id": "GIPR_MOUSE", "id": "Q0P543-1", "name": "Gastric inhibitory polypeptide receptor", "aln": "---MPLRLLLLLLWLWG--LQWAETDSEGQTTTGELYQRWEHYGQECQKMLETTEPPSGLACNGSFDMYACWNYTAANTTARVSCPWYLPWFRQVSAGFVFRQCGSDGQWG------SWRDHTQCENPEKNGAFQD-QTLILERLQIMYTVGYSLSLTTLLLALLILSLFRRLHCTRNYIHMNLFTSFMLRAAAILTRDQLLPPLGPYTG---DQAPTPWNQALAACRTAQIMTQYCVGANYTWLLVEGVYLHHLLVIVGRSEKGHFRCYLLLGWGAPALFVIPWVIVRYLRENTQCWERNEVKAIWWIIRTPILITILINFLIFIRILGILVSKLRTRQMRCPDYRLRLARSTLTLVPLLGVHEVVFAPVTEEQVEGSLRFAKLAFEIFLSSFQGFLVSVLYCFINKEVQSEIRQGWRHRRLRLSLQEQRPRPHQELAPR--------------AVPLSSAC----------------------------REAAVGNALPSGMLHVPGDEV----LESYC", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P48546-1", "uniprot_id": "GIPR_HUMAN", "id": "P48546-1", "name": "Gastric inhibitory polypeptide receptor", "aln": "MTTSPILQLLLRLSLCGLLLQRAETGSKGQ-TAGELYQRWERYRRECQETLAAAEPPSGLACNGSFDMYVCWDYAAPNATARASCPWYLPWHHHVAAGFVLRQCGSDGQWG------LWRDHTQCENPEKNEAFLD-QRLILERLQVMYTVGYSLSLATLLLALLILSLFRRLHCTRNYIHINLFTSFMLRAAAILSRDRLLPRPGPYLG---DQALALWNQALAACRTAQIVTQYCVGANYTWLLVEGVYLHSLLVLVGGSEEGHFRYYLLLGWGAPALFVIPWVIVRYLYENTQCWERNEVKAIWWIIRTPILMTILINFLIFIRILGILLSKLRTRQMRCRDYRLRLARSTLTLVPLLGVHEVVFAPVTEEQARGALRFAKLGFEIFLSSFQGFLVSVLYCFINKEVQSEIRRGWHHCRLRRSLGEE-QRQLPERAFR--------------ALPSGSGP----------------------------GEVPTSRGLSSGTLPGPGNEAS-RELESYC", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "E7FCX8-1", "uniprot_id": "E7FCX8_DANRE", "id": "E7FCX8-1", "name": "", "aln": "---MKSTSTIFLLTLAV--LCRAER-VSGK-TVKDTVQEWNRYRSECILKISSQPTPSGLFCKSMFDMYACWTDGVPNTTVKVPCPWYLPWHDQVRNGFVSRECGPDGQWLTVNHSSTWRDHSQCNADGRQQIAQENQMMVLAYFRVMYTVGYSLSLASLSLALIILLIFRKLRCTRNYIHTNLFASFILRAVSILTRDALLMKDAPEFRDNKDVSIVLSDQVMSGCRVAQVLMQYCVGANYYWLLVEGLYLHNLLVLMVFSENSYICVYFFIGWGTPVLFVVPWIIVRYLYENTRCWEINENMAYWWIIRTPILLAILVNFFIFIRIILILISKLKAHQMRYTDYKFRLAKSTLTLIPLLGIHEVVFAVMTEEQTEGVLRNVNLFFELFFNSFQGFLVAILYCFVNKEVQSEIKKKWQRWKLGISILDDQRNTGSNTQPVGTGPQCHHDPACSPECPLDSGSQLSSDPTPSIQHHYHPGAKKGKAYCYISARKQVVNGLDVPALPQCGGEGAGMYSESYC", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :: * * * ** .*: *. : *.*::* ** : : .**** *:. ****.** ..*:*.:..*******. :* *** *:**.**** ****:**: :: : * ::* ::::*********::* ***:** :**:*:******* ***:**:*** :**:** ** .* : : . :*.::.**.**:: ******** ******:*** ***:: **:.:: *:::***:*.***:**:***** ***:*** ** * *********::**:**:*****: **:***:::*** **::***:*****:****:****** :****..* ** .:* **:*:.*******::****:********: :* *: :: . * .*. . ..* * *.* ****", "identical_positions": 230, "similar_positions": 111, "identity": "44.15%" }, { "cls_id": "homologset.agr.MGI:1352754", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9Y696-1", "uniprot_id": "CLIC4_HUMAN", "id": "Q9Y696-1", "name": "Chloride intracellular channel protein 4", "aln": "MALSMPLNGLKEEDKE----PLIELFVKAG-SDGESIGNCPFSQR----LFMILWLKGVVFSVTTVDLKRKPADLQNLAPGTHPPFITFNSEVKTDVNKIEEFLEEVLCPPKYLKLSPKHPESNTAGMDIFAKFSAYIKNSRPEANEALERGLLKTLQKLDEYLNSPLPDEIDENSMEDIKFSTRKFLDGNEMTLADCNLLPKLHIVKVVAKKYRNFDIPKEMTGIWRYLTNAYSRDEFTNTCPSDKEVEIAYSDVAKRLTK--------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9QYB1-1", "uniprot_id": "CLIC4_MOUSE", "id": "Q9QYB1-1", "name": "Chloride intracellular channel protein 4", "aln": "MALSMPLNGLKEEDKE----PLIELFVKAG-SDGESIGNCPFSQR----LFMILWLKGVVFSVTTVDLKRKPADLQNLAPGTHPPFITFNSEVKTDVNKIEEFLEEVLCPPKYLKLSPKHPESNTAGMDIFAKFSAYIKNSRPEANEALERGLLKTLQKLDEYLNSPLPDEIDENSMEDIKFSTRRFLDGDEMTLADCNLLPKLHIVKVVAKKYRNFDIPKGMTGIWRYLTNAYSRDEFTNTCPSDKEVEIAYSDVAKRLTK--------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9Z0W7-1", "uniprot_id": "CLIC4_RAT", "id": "Q9Z0W7-1", "name": "Chloride intracellular channel protein 4", "aln": "MALSMPLNGLKEEDKE----PLIELFVKAG-SDGESIGNCPFSQR----LFMILWLKGVVFSVTTVDLKRKPAHLQNLAPGTHPPFITFNSEVKTDVNKIEEFLEEVLCPPKYLKLSPKHPESNTAGMDIFAKFSAYIKNSRPEANEALERGLLKTLQKLDEYLNSPLPGEIDENSMEDIKSSTRRFLDGDEMTLADCNLLPKLHIVKVVAKKYRNFDIPKGMTGIWRYLTNAYSRDEFTNTCPSDKEVEIAYSDVAKRLTK--------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9VY78-1", "uniprot_id": "CLIC_DROME", "id": "Q9VY78-1", "name": "Chloride intracellular channel Clic", "aln": "MSEVESQQSQETNGSSKFDVPEIELIIKASTIDGRRKGACLFCQEYFMDLYLLAELKTISLKVTTVDMQKPPPDFRTNFEATHPPILIDNGLAILENEKIERHIMKNIPGGYNLFVQDKEVATLIENLYVKLKLMLVKKD------EAKNNALLSHLRKINDHLS----------------ARNTRFLTGDTMCCFDCELMPRLQHIRVAGKYFVDFEIPTHLTALWRYMYHMYQLDAFTQSCPADQDIINHYKLQQSLKMKKHEELETPTFTTYIPIDISE", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*: . :. : :... * ***::**. **. * * *.*. *::: ** : :.*****::: *..::. .****:: *. . : :***..: : : * :. *. : .: : *: *: ** :..**. *:*::::*. . :** *: * **:*:*:*: ::*..* : :*:**. :*.:***: : *. * **::**:*::: *. . * ", "identical_positions": 68, "similar_positions": 89, "identity": "24.11%" }, { "cls_id": "homologset.agr.MGI:1352755", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I6GJ39-1", "uniprot_id": "A0A8I6GJ39_RAT", "id": "A0A8I6GJ39-1", "name": "", "aln": "MPNPPVPLLSAANSMERRDGSDVPSTSQRGEVKMDPGSKKEDFLLLEDEKFDFDLSLSSSSANE----DDEVFFGPVGHKERCIAASLDLNRQVPEQPLAPGSGSPCTWSPLTGEKFVEVYKEAHLLALQIECHSRREVAQAAKPRSAVSQAKETFVQDSQLKISLFEKEQKRDKSPLSLKRETFCLPSS--RAQPLLGEPQLLASPGLPNSPLPAGPVQTQSTQGPPCSSQ----------PPSQAGPQRRIMSKLQPPRALPVRGRNLFLATEKLKKEVPASLQQTKPLNEKGSQSDVLLDKPS----TAPDAASREGRPGKRSLPVPGKLGLKK-TLLKPPGYTSN-LTKKSSTSGSASSLVSGVGRSPTAGKAKSSE-LSSIPASSSRRQSVTSKLGRVGLATSHQALPAAPARAFCRQAKKADAAQTVAEQPKALTPSPLAQQPQTPKHKGPRVDLD---TETCQLNKTVSIKRQDSSLGCKTEAVSTTTNPFKVPQFSVGESPDRVTPKISRTHRLQSWTPAGRV-VSSTPVRRLSGLTPQGLPSSMRTPLSTRRMSVLPTPASRRLSGLPLTAPQSMPRALVSPLCVPARRLSSEPRRRSTVRSELMQESSSNGSAGQSQGLSSDESSSPPSSVPQALNFSPEKSDFPPSQGSSTGTGQGEAEPHEDMHPSEVPGGECSSTPSEGLLLDIKLDQLTIAPEAGDRDLADCPLIDFSNTPESNMALGPSSWPLIDLIMNTPNMGRSDVGKPPKAELGQLIDLGSPLIQLSPEADKEN-VDSPLLKF--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8R080-1", "uniprot_id": "GTSE1_MOUSE", "id": "Q8R080-1", "name": "G2 and S phase-expressed protein 1", "aln": "---------------------------------MDAGSKKEDFLLLEDEKFDFDLSLSSSSTNE----DDEVFFGPVGHKERCIAASLDLNRRVPGQPLAPGSGSPCTLSPLTGEKFVEVYKEAHLLALQIESHSRREVAQAATPQNPVNQGKETFVQDSQLKVSLFEKEQKRDRSPMSLKRETFCLPSS--RVQPPMGEPQLLASPGLLSSPVSAGPAQTQSNQGLPCSSQPLPRESSTSQPPSQAGPQKRITSKLQPPRALPVRGRNLHLATEKLKKEVPASIQRTKLVNEKGSQSDVLQDKPS----TAPDAASREGHPGKRSLPIPGKLGLKK-TLLKPPGYTGN-LTRKSSTSGSASSLESGVYRSSVAGKAKSSEQRSSIPASGSQRRTSTSKSGRIGPAASRQALPAAPARVFGRQANKADAAQTVAEQPKVPTLSPLTQQPQTPEQRGPRLDPD---TETPQLNKTVSIKRRDSYLSCKTEAVSTTTNPFKVPQFSVGESPGGVTPKFSRTHRLQSWTPASRV-VSSTPVRRSSGTTPQGLPGSMRTPLSTRRMSVLPTPASRRLSSLPLMAPQSMPRALVSPLCVPARRLSSEPRRRSTVRAELTQESSGSGSGGQAQGLSSDESSSPPSSVPQALNFSPEKSASPPPQGSSTGAAQGEAEPPEDTLPSEVHGGGCSHTPSEGLLLDLKLDQLTITPEAGGRDLADCPLIDFSNTPESNTALGPSSWPLIDLIMNTPDMGRNDVGKPAKAELGQLIDLGSPLIQLSPEADKEN-VDSPLLKF--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9NYZ3-1", "uniprot_id": "GTSE1_HUMAN", "id": "Q9NYZ3-1", "name": "G2 and S phase-expressed protein 1", "aln": "--------------MEGGGGRDEPSACRAGDVNMD-DPKKEDILLLADEKFDFDLSLSSSSANE----DDEVFFGPFGHKERCIAASLELNNPVPEQPPLPTSESPFAWSPLAGEKFVEVYKEAHLLALHIESSSRNQAAQAAKPEDPRSQGVERFIQESKLKINLFEKEKEMKKSPTSLKRETYYLSDSP-LLGPPVGEPRLLASS--PALPSSGAQARLTRAPGPPHSAHALPRESCTAHAASQAATQRKPGTKLLLPRAASVRGRSIPGAAEKPKKEIPASPSRTKIPAEKESHRDVLPDKPAPGAVNVPAAGSHLGQ-GKRAIPVPNKLGLKK-TLLKAPGSTSN-LARKSS-SGPVWSGASSACTSPAVGKAKSSE-FASIPANSSRPLSNISKSGRMGPAMLRPALPAGPVGASSWQAKRVDVSELAAEQLTAP-PSASPTQPQTPEGGGQWLNSSCAWSESSQLNKTRSIRRRDSCLNSKTKVMPTPTNQFKIPKFSIGDSPDSSTPKLSRAQRPQSCTSVGRVTVHSTPVRRSSGPAPQSL-------LSAWRVSALPTPASRRCSGLPPMTPKTMPRAVGSPLCVPARRRSSEPRKNSAMRTEPTRESNRK-TDSRLVDVSPDRGS-PPSRVPQALNFSPEESDSTFSKSTATEVAREEAKP----------GG--DAAPSEALLVDIKLEPLAVTPDAASQPLIDLPLIDFCDTPEAHVAVGSESRPLIDLMTNTPDMNKN-VAKPS-PVVGQLIDLSSPLIQLSPEADKEN-VDSPLLKF--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0ACD6B6C1-1", "uniprot_id": "A0ACD6B6C1_DANRE", "id": "A0ACD6B6C1-1", "name": "", "aln": "----------------------------------MASLSHSDFVSLAEEKFDFDVSLSPGSSKGDYEVEDEVFVGPVSHKEKCISHGVETHVKDN-ISSGPSLGEEPSWSPLTGEKFDEICKEAQQLASHIEQTITDSAAESSVVS---SCQTETFEDDAATKLNLFSKPADILSP---IKRETFLVQDSPMKQLPPAIQKRMMKTNGKAGFGKPRLSTSSPVRPAVTQHKLASKSKVLMANSGVLPSKPTGQGNSRLSCSAKPLPANKTRLPPPSRGNFGLKRSPSSRNTSRAGSSEDLLSDNTSVAS-DVSDSSLNTSLPGRSSIPARNKTELRAPSALKAPSLQNSRVVDRRRNTSSSSSSVSSINSSLTVSPGSKAKLNSSLNSSTNSIGTRSQSSVSMLPSSSRKSSVVARNPDPVVSRRTSITTQNRRTSEIMPRPVKATPMKKTEPLPPQQLQTP-----AKTSSIPASAAKVGSAFRGNPKLRLSVVPTPTNYMKAVHKSEASTSPDVPRIMKPKRLLTACSV----DSIPDHLAAPPAGLLTPSAVASKLRRPSALPTPVNRRVSGIPALTPKSVSR-LSKPVQITQR---SSTADEVPTCLSPENKKESEKAEYKQPSVSIEETCPPADLQPCSLLFNMEDESEGSPACEPADMEPPPEPPSHQPEPS-------SCDPEPPSPVDIKSPAPPTTADMHKQHPQKNMEKKEVLLVDAPAPTRQLSEKLLIDLSNTPDLIKTSSGKPW---AGQLIDLSSPLIKWSPENKKRSENVAPLIDLSF", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . .:.*:: * :******:***..*:: :****.**..***:**: .:: : . * . : ***:**** *: ***: ** :** ..*::: . * * ::: *:.**.* . . :****: : .* * : ::: : . . . . . .. .. * .: ... .. . : :: . * *:* *:.: .. :. . . *: ::* .* *: : **.*. .. :. : :.. * *. * ... ...:: :*: :. . : .. : : : : .. . . .:: . . :* :: : . . * : .* : :.: : . . :: .* :*...* : : .. * .: . .* .* . * *.****..** *.:* :*:::.* : .*: :. * *.. . . . .:.. . : : .:* :. . *.. * :* *. *.. . .: * . *. :*:* . :.: : . . :: . * *: : ***:: :. .** ******.****: *** .*.. :**:.: ", "identical_positions": 125, "similar_positions": 232, "identity": "15.76%" }, { "cls_id": "homologset.agr.MGI:1352756", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8K394-1", "uniprot_id": "PLCL2_MOUSE", "id": "Q8K394-1", "name": "Inactive phospholipase C-like protein 2", "aln": "MAECGRG-AAGGALPTSPSPALGAKGALKAGAGEGGGGGGGGRLGHGRARYDSGGVSNGDCSLGVSGDEARTSPGRGPLGVALARTPSPAAGPVPRDSKPGGLPRRSSIIKDGTKQKRERKKTVSFSSMPTEKKISSASDCINSMVEGSELKKVRSNSRIYHRYFLLDADMQSLRWEPSKKDSEKAKIDIKSIKEVRTGKNTDIFRSNGISEQISED--CAFSVIYGEN--YESLDLVANSADVANIWVTGLRYLISYGKHTLD--MLESSQDNMRTSWISQMFSEIDVDGLGHITLCHAVQCIRNLNPGLKTSKIELKFKELHKSKDKAGTEITKEEFIEVFHELCTRPEIYFLLVQFSSN-KEFLDTKDLMMFLEAEQGVAHINEEISLEIIHKYEPSKEGQEKGWLSIDGFTNYLMSPDCYIFDPEHKKVCQDMKQPLSHYFINSSHNTYLIEDQFRGPSDITGYIRALKMGCRSVELDVWDGPDNEPVIYTGHTMTSQIVFRSVIDIINKYAFFASEYPLILCLENHCSIKQQKVMVQHMKKILGDKLYTTSPNMEESYLPSPDVLKGKILIKAKKLSSNCSGVEG------------------DVTDEDEGAEMSQRMGKENVEQPNHVPVKRFQLCKELSELVSICKSVQFKEFQVSFQVQKYWEVCSFNEVLASKYANENPG--DFVNYNKRFLARVFPSPMRIDSSNMNPQDFWKCGCQIVAMNFQTPGLMMDLNVGWFRQNGN-------CGYVLRPAIMR---EEVSFFSANTKDSVPGVSPQLLHIKIISGQNFPKPKGSGAKGDVVDPYVYVEIHG-------------IPADCAEQRTKTVNQNGDAPIFDESFEFQINLPELAMVRFVVLDDDYIGDEFIGQYTIPFECLQTGYRHVPLQSLTGEVLAHASLFVHVAITNRRGGGKPHKRGLSVRKGKKSREYASLRTLWIKTVDEVFKNAQPPIRDATDLRENMQNAVVSFKELCGLSSVANLMQCMLAVSPRFLGPDNNPLVVLNLSEPYPTMELQAIVPEVLKKIVTTYDMMMQSLKALIENADAVYEKIVHCQKAAMEFHEHLHSIGTKEGLKERKLQKAVESFTWNITILKGQADLLKYAKNETLENLKQIHFAAVSCGLNKPGTENSEAQKPRRSLEAIPEKASDENGD", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "F1M324-1", "uniprot_id": "F1M324_RAT", "id": "F1M324-1", "name": "Phosphoinositide phospholipase C", "aln": "MAECGRG-AAGGALPTSPGPALGAKGALKAGAGEGGGSGGGGRLGHGRARYDSGGVSNGDCSLGVSGDEARASPARGPRGVALARTPSPAAGPVPRDSKPGGLPRRSSIIKDGTKQKRERKKTVSFSSMPTEKKISSASDCINSMVEGSELKKVRSNSRIYHRYFLLDADMQSLRWEPSKKDSEKAKIDIKSIKEVRTGKNTDIFRSNGISEQISED--CAFSVIYGEN--YESLDLVANSADVANIWVTGLRYLISYGKHTLD--MLESSQDNMRTCWVSQMFSEIDVDDLGHITLCNAVQCIRNLNPGLKTSKIELKFKELHKSKDKTGTEITKEEFVEVFHELCTRPEIYFLLVQFSSN-KEFLDTKDLMMFLEAEQGVAHINEEISLEIIHKYEPSKEGQEKGWLSIDGFTNYLMSPDCYIFDPEHKKVCQDMKQPLSHYFINSSHNTYLIEDQFRGPSDITGYIRALKMGCRSVELDVWDGPDNEPVIYTGHTMTSQIVFRSVIDIINKYAFFASEYPLILCLENHCSIKQQKVMVQHMKKILGDKLYTTSPNMEESYLPSPDVLKGKILIKAKKLSSNCSGVEG------------------DVTDEDEGAEMSQRMGKENVEQPNHVPVKRFQLCKDLSELVSICKSVQFKEFQVSFQVQKYWEVCSFNEVLASKYANENPG--DFVNYNKRFLARVFPSPMRIDSSNMNPQDFWKCGCQIVAMNFQTPGLMMDLNIGWFRQNGN-------CGYVLRPAIMR---EEVSFFSANTKDSVPGVSPQLLHIKIISGQNFPKPKGSGAKGDVVDPYVYVEIHG-------------IPADCAEQRTKTVNQNGDAPMFDESFEFQINLPELAMVRFVVLDDDYIGDEFIGQYTIPFECLQTGYRHVPLQSLTGEVLAHASLFVHVAITNRRGGGKPHKRGLSVRKGKKSREYASLRTLWIKTVDEVFKNAQPPIRDATDLRENMQNAVVSFKELCGLSSVANLMQCMLAVSPRFLGPDNTPLVVLNLSEPYPTMELQAIVPEVLKKIVTTYDMMIQSLKALIENADAVYEKIVHCQKAAMEFHEHLHSIGTKEGLKERKLQKAVESFTWNITILKGQADLLKYAKNETLENLKQIHYAAVSCGLNKPGTENSEAQKPRRSLEVIPEKTSDENGD", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9UPR0-1", "uniprot_id": "PLCL2_HUMAN", "id": "Q9UPR0-1", "name": "Inactive phospholipase C-like protein 2", "aln": "MAECGRGGAAGGALPTSPGPALGAKGALKAGVGEGG--GGGGRLGHGRARYDSGGVSNGDCSLGVSGDEARASPTRGPRGVALAPTPSAVVCTLPRESKPGGLPRRSSIIKDGTKQKRERKKTVSFSSMPTEKKISSASDCINSMVEGSELKKVRSNSRIYHRYFLLDADMQSLRWEPSKKDSEKAKIDIKSIKEVRTGKNTDIFRSNGISDQISED--CAFSVIYGEN--YESLDLVANSADVANIWVTGLRYLISYGKHTLD--MLESSQDNMRTSWVSQMFSEIDVDNLGHITLCNAVQCIRNLNPGLKTSKIELKFKELHKSKDKAGTEVTKEEFIEVFHELCTRPEIYFLLVQFSSN-KEFLDTKDLMMFLEAEQGVAHINEEISLEIIHKYEPSKEGQEKGWLSIDGFTNYLMSPDCYIFDPEHKKVCQDMKQPLSHYFINSSHNTYLIEDQFRGPSDITGYIRALKMGCRSVELDVWDGPDNEPVIYTGHTMTSQIVFRSVIDIINKYAFFASEYPLILCLENHCSIKQQKVMVQHMKKLLGDKLYTTSPNVEESYLPSPDVLKGKILIKAKKLSSNCSGVEG------------------DVTDEDEGAEMSQRMGKENMEQPNNVPVKRFQLCKELSELVSICKSVQFKEFQVSFQVQKYWEVCSFNEVLASKYANENPG--DFVNYNKRFLARVFPSPMRIDSSNMNPQDFWKCGCQIVAMNFQTPGLMMDLNIGWFRQNGN-------CGYVLRPAIMR---EEVSFFSANTKDSVPGVSPQLLHIKIISGQNFPKPKGSGAKGDVVDPYVYVEIHG-------------IPADCAEQRTKTVHQNGDAPIFDESFEFQINLPELAMVRFVVLDDDYIGDEFIGQYTIPFECLQTGYRHVPLQSLTGEVLAHASLFVHVAITNRRGGGKPHKRGLSVRKGKKSREYASLRTLWIKTVDEVFKNAQPPIRDATDLRENMQNAVVSFKELCGLSSVANLMQCMLAVSPRFLGPDNTPLVVLNLSEQYPTMELQGIVPEVLKKIVTTYDMMIQSLKALIENADAVYEKIVHCQKAAMEFHEHLHSIGTKEGLKERKLQKAVESFTWNITILKGQADLLKYAKNETLENLKQIHFAAVSCGLNKPGTENADVQKPRRSLEVIPEKANDETGE", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P32383-1", "uniprot_id": "PLC1_YEAST", "id": "P32383-1", "name": "1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase 1", "aln": "MTESAID-----------DQRFNLTKELQR-----------------HSCRDQGKITQKDDALDFISYSSFQSSFN-------TDQKSANNGSTVRRSIRSIFRRAAELPRVHMGPLTYSHGINELVNKKLRKDCDLSTLCR-VLQRGIRMIRMTRRRRKFYEFKLINNNGQIIWKDGSK------YLELDSVKDIRIGDTASTYQEEVDPKRLRSDSKLWIAIIYKVSNKLKALHVVALNELDFNTFLSCICGLVKLRRELMESILLPDNSQFARIHWQITVSEKEEDEKKDTLSFADVKKLCDKFHIYVSTGQLLEFFQLADINHNGLLNYFEFEKFIKILKN---RKEVNMIWSKFTKPPHSHLSFENFFQFLITEQ-----HEQVDRQTAWSYFIKYREPTQLTMGQDGFTKFLKE-QPYLVEVKEELYS----KPLNHYFIASSHNTYLLGKQIAETPSVEGYIQVLQQGCRCVEIDIWDG-ENGPVVCHG-FLTSAIPLKTVIRVIKKYAFITSPYPLIISLEINCNKDNQKLASLIMREVLAEQLYFVGTRTDK--LPSPRELKHKILLKSKKTSEATRGLSVNEPFPSSFSSSYESANEQELRMKDDSTNSSSATNSSSMQRIKRIGLKKHADIINDVSNISGIHGIKFRNFSLP-ESKTIAHCFSLNERKVEYMIKDKHLKLSLDKHNRRYLMRVYPHVLRYKSSNFNPIPFWKAGVQMVATNWQTNDIGQQLNLAMFQILDHQPDGSFKSGYVLKPKKLLPVVTKAKMIPLIYEHFENGSDPVTVKIRILSTQLLPRLNDTSPSRNNTNSFVKVEFHTDDEPTMPISIDKGTRISATEASTKSSQGNGFNPIWDAEVSITLKDTDLTFIKFMVISEETQ----IASVCLKLNYLRMGYRHIPLFNMEGEQYIFCTLFIHTQIL------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*:*.. . . :. . *: :: *.* ::: * :*.. . .: *. . : *. . * * . : * :.: : : .: . .*. . :: * : .* .: :: . * ::.: *:: : * : : ** :::.*:*::* *..:. ::.: ..:: .* :::** . ::*.:** . * ::: : *:. :. :: :* ...: * * : .: : : . :::... : ::: :.*.:: *: . .:: . . *:*:::::: * *: :: :*:. :..*. :::: ** :** :*::. : .* . . : :. ****::* . : *:.: :.: . :**.**** *******: .*: ...: ***:.*: ***.**:*:*** :* **: * :** * :::** :*:****::* ****:.** :*. .:**: *:::*.::** .... :: **** ** ***:*:** *. *:. :: :*:.:: *. ....::: :.: :*:. : . :* :.::*::*.:. : :. . *:** .. ::: .: ::*:*:* **:* :* .***:** ***.* *:** *:** .: :**:. *: .: .****:* : :..::. :. * .* ::*:*:* * :*: :.:... : .:.:* **:* ..:* **: : ** *::* ...: :: .:*::::*:*:.:: *.. : :: *: ****:** .: ** ..:**:*. * ", "identical_positions": 198, "similar_positions": 354, "identity": "16.79%" }, { "cls_id": "homologset.agr.MGI:1352757", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9JKF1-1", "uniprot_id": "IQGA1_MOUSE", "id": "Q9JKF1-1", "name": "Ras GTPase-activating-like protein IQGAP1", "aln": "-----------------------------------------------------------------------------------------------------------------------MSAAEEVDGLGVVRPHYGSVLDNERLTAEEMDERRRQNVAYEYLCHLEEAKRWMEACLGEDLPPTTELEEG--LRNGVYLAKLGNFFSPKVVSLKKIYDREQTRYKATGLHFRHTDNVIQWLNAMDEIGLPKIFYPETTDIYDRKNMPRCIYCIHALSLYLFK--LGLAPQIQDLYGKVDFTEEEINNMKIELEKYGIQMPAFSKIGGILANELSVDEAALHAAVIAINEAIDRR-VAADTFTALKNPNAMLVNLEEGLAPTYQDVLYQAKQDKMTNAKNRTENSDRERDVYEELLTQAEIQGNVNKVNTSSALANISLALEQGCAVTLLKALQSLALGLRGLQTQNSDWYMKQLQSDLQQKRQSGQTDPLQKEEVQAGVDAANSAAQQYQRRLAAVAAINAAIQKGIAEKTVLELMNPEAQLPQVYPFAADLYQKELATLQQQSPEHSLTHPELTVAVEMLSSVALINRALESGDMTTVWKQLSSSVTGLTNIEEENCQRYLDELMKLKAQAHAENNAFITWNDIQACVDHVNLVVHEEHERILAIGLINEALDEGDAQKTLQALQIPAAKLEGVLAEVAQHYQDTLIRAKREKAQETQDESAVLWLDEIQGGIWQSNKDTQEAQRFALGISAINEAVDSGDVGRTLSALRSPDVGLYGVIPECGETYQSDLAEAKKKRLAAGDNNSKWVKHWVKGGYHYYHNLETQAGGWAEPPDFVQNSVQLSREEIQSSISGVTAAYNREQLWLANEGLITKLQACCRGYLVRQEFRSRMNFLKKQIPAITCIQSQWRGYKQKKAYQDRLAYLHSHKDEVVKIQSLARMHQARKRYRDRLQYFRDHINDIIKIQAFIRANKARDDYKTLINAEDPPMIVVRKFVHLLDQSDQDFQEELDLMKMREEVITLIRSNQQLENDLNLMDIKIGLLVKNKITLQDVVSHSKKLTKKNKEQLSDMMMINKQKGGLKALSKEKREKLEAYQHLFYLLQTNPTYLAKLIFQMPQNKSTKFMDSVIFTLYNYASNQREEYLLLRLFQTALQEEIKSKVDQIQEIVTGNPTVIKMVVSFNRGARGQNALRQILAPVVKEIMDDKSLNIKTDPVDIYKSWVNQMESQTGEASKLPYDVTPEQALSHEEVKTRLDNSIRNMRAVTDKFLSAIVSSVDKIPYGMRFIAKVLKDSLHEKFPDAGEDELLKIIGNLLYYRYMNPAIVAPDAFDIIDLSAGGQLTTDQRRNLGSIAKMLQHAASNKMFLGDNAHLSIINEYLSQSYQKFRRFFQVACDVPELQDKFNVDEYSDLVTLTKPVIYISIGEIINTHTLLLDHQDAIAPEHNDPIHELLDDLGEVPTIESLIGESCGNSNDPNKEALAKTEVSLTLTNKFDVPGDENAEMDARTILLNTKRLIVDVIRFQPGET-LTEILETPATNEQEAEHQRAMQRR-AIRDAKTPDKMKKSKPMKEDNNLSLQEKKEKIQTGLKKLTELGTVDPKNRYQELINDIAKDIRNQRRYRQRRKAELVKLQQTYSALNSKATFYGEQVDYYKSYIKTCLDN----LASKGKVSKKPREMKGKKSKKIS---LKYTAARLHEKGVLLEIED------------LQANQFKNVIFEIGPTEEVG-DFEVKAKFMG----VQMETFMLHYQDLLQLQYEG-VAVMKLFDR-AKVNVNLLIFLLNKKFYGK---", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8I6AJK7-1", "uniprot_id": "A0A8I6AJK7_RAT", "id": "A0A8I6AJK7-1", "name": "Ras GTPase-activating-like protein IQGAP1", "aln": "MARGGALRTATARALGRSCCCYGRPRLQGLCSSSPETGTRPPCPPRRRSMAWVWSGRTMAVSTGYLGVRGRGFPRGSAERVRGVAWDRTDPEEQPAVWLVARLASEPSRAPEAAGRNLEASAFARRRGRGAPPRASTAVLDNERLTAEEMDERRRQNVAYEYLCHLEEAKRWMEACLGEDLPPTTELEEG--LRNGVYLAKLGNFFSPKVVSLKKIYDREQTRYKATGLHFRHTDNVIQWLNAMDEIGLPKIFYPETTDIYDRKNMPRCIYCIHALSLYLFK--LGLAPQIQDLYGKVDFTEEEINNMKIELEKYGIQMPAFSKIGGILANELSVDEAALHAAVIAINEAIDHR-VAADTFTALKNPNAMLVNLEEALAPTYQDVLYQAKQDKMTNAKNRTENSDRERDVYEELLTQAEIQGNVNKVNTSSALANINLALEQGCALTLLKALQSVALGLRGLQTQNSDWYLKQLQSDLQQKRQSGQTDPLQKEEVQAGVDAANGAAQQYQRRLAAVAAINAAIQKGIAEKTVLELMNPEAQLPQVYPFAADLYQKELATLQQQSPEHSLTHPELTVAVEMLSSVALINRALESGDMNTVWKQLSSSVTGLTNIEEENCQRYLDELMKLKAQAHAENNEFVTWNDIQACVDHVNLVVHEEHERILAIGLINEALDEGDAQKTLQALQIPAAKLEGVLPEVAQHYQDTLIRAKREKAQETQDESAVLWLDEIQGGIWQSNKDTQEAQRFALGIFAINEAVESGDVGRTLSALRSPDVGLYGVIPECGETYQSDLAEAKKKRLAAGDNNSKWVKHWVKGGYHYYHNLETQAGGWAEPPDFVQNSVQLSREEIQSSISGVTAAYNREQLWLANEGLITKLQACCRGYLVRQEFRSRMNFLKKQIPAITCIQSQWRGYKQKKAYQDRLAYLHSHKDEVVKIQSLARMHQARKRYRDRLQYFRDHINDIIKIQAFIRANKARDDYKTLINAEDPPMIVVRKFVHLLDQSDQDFQEELDLMKMREEVITLIRSNQQLENDLNLMDIKIGLLVKNKITLQDVVSHSKKLTKKNKEQLSDMMMINKQKGGLKALSKEKREKLEAYQHLFYLLQTNPTYLAKLIFQMPQNKSTKFMDSVIFTLYNYASNQREEYLLLRLFQTALQEEIKSKVDQIQEIVTGNPTVIKMVVSFNRGARGQNALRQILAPVVKEIMDDKSLNIKTDPVDIYKSWVNQMESQTGEASKLPYDVTPEQALSHEEVKTRLDNSIRNMRAVTDKFLSAIVSSVDKIPYGMRFIAKVLKDSLHEKFPDAAEDELLKIIGNLLYYRYMNPAIVAPDAFDIIDLSAGGQLTTDQRRNLGSIAKMLQHAASNKMFLGDNAHLSIINEYLSQSYQKFRRFFQAACDVPELQDKFNVDEYSDLVTLTKPVIYISIGEIINTHTLLLDHQDAIAPEHNDPIHELLDDLGEVPTIESLIGESCGNSNDPSKEALAKTEVSLTLTNKFDVPGDENAEMDARTILLNTKRLIVDVIRFQPGET-LTEILETPATNEQEAEHQRAMQRR-AIRDAKTPDKMKKSKPMKEDNNLSLQEKKEKIQTGLKKLTELGTVDPKNRYQELINDIAKDIRNQRRYRQRRKAELVKLQQTYSALNSKATFYGEQVDYYKSYIKTCLDN----LASKGKVSKKPREMKGKKSKKIS---LKYTAARLHEKGVLLEIED------------LQANQFKNVIFEIGPTEEVG-DFEVKAKFMG----VQMETFMLHYQDLLQLQYEG-VAVMKLFDR-AKVNVNLLIFLLNKKFYGK---", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P46940-1", "uniprot_id": "IQGA1_HUMAN", "id": "P46940-1", "name": "Ras GTPase-activating-like protein IQGAP1", "aln": "-----------------------------------------------------------------------------------------------------------------------MSAADEVDGLGVARPHYGSVLDNERLTAEEMDERRRQNVAYEYLCHLEEAKRWMEACLGEDLPPTTELEEG--LRNGVYLAKLGNFFSPKVVSLKKIYDREQTRYKATGLHFRHTDNVIQWLNAMDEIGLPKIFYPETTDIYDRKNMPRCIYCIHALSLYLFK--LGLAPQIQDLYGKVDFTEEEINNMKTELEKYGIQMPAFSKIGGILANELSVDEAALHAAVIAINEAIDRR-IPADTFAALKNPNAMLVNLEEPLASTYQDILYQAKQDKMTNAKNRTENSERERDVYEELLTQAEIQGNINKVNTFSALANIDLALEQGDALALFRALQSPALGLRGLQQQNSDWYLKQLLSDKQQKRQSGQTDPLQKEELQSGVDAANSAAQQYQRRLAAVALINAAIQKGVAEKTVLELMNPEAQLPQVYPFAADLYQKELATLQRQSPEHNLTHPELSVAVEMLSSVALINRALESGDVNTVWKQLSSSVTGLTNIEEENCQRYLDELMKLKAQAHAENNEFITWNDIQACVDHVNLVVQEEHERILAIGLINEALDEGDAQKTLQALQIPAAKLEGVLAEVAQHYQDTLIRAKREKAQEIQDESAVLWLDEIQGGIWQSNKDTQEAQKFALGIFAINEAVESGDVGKTLSALRSPDVGLYGVIPECGETYHSDLAEAKKKKLAVGDNNSKWVKHWVKGGYYYYHNLETQEGGWDEPPNFVQNSMQLSREEIQSSISGVTAAYNREQLWLANEGLITRLQARCRGYLVRQEFRSRMNFLKKQIPAITCIQSQWRGYKQKKAYQDRLAYLRSHKDEVVKIQSLARMHQARKRYRDRLQYFRDHINDIIKIQAFIRANKARDDYKTLINAEDPPMVVVRKFVHLLDQSDQDFQEELDLMKMREEVITLIRSNQQLENDLNLMDIKIGLLVKNKITLQDVVSHSKKLTKKNKEQLSDMMMINKQKGGLKALSKEKREKLEAYQHLFYLLQTNPTYLAKLIFQMPQNKSTKFMDSVIFTLYNYASNQREEYLLLRLFKTALQEEIKSKVDQIQEIVTGNPTVIKMVVSFNRGARGQNALRQILAPVVKEIMDDKSLNIKTDPVDIYKSWVNQMESQTGEASKLPYDVTPEQALAHEEVKTRLDSSIRNMRAVTDKFLSAIVSSVDKIPYGMRFIAKVLKDSLHEKFPDAGEDELLKIIGNLLYYRYMNPAIVAPDAFDIIDLSAGGQLTTDQRRNLGSIAKMLQHAASNKMFLGDNAHLSIINEYLSQSYQKFRRFFQTACDVPELQDKFNVDEYSDLVTLTKPVIYISIGEIINTHTLLLDHQDAIAPEHNDPIHELLDDLGEVPTIESLIGESSGNLNDPNKEALAKTEVSLTLTNKFDVPGDENAEMDARTILLNTKRLIVDVIRFQPGET-LTEILETPATSEQEAEHQRAMQRR-AIRDAKTPDKMKKSKSVKEDSNLTLQEKKEKIQTGLKKLTELGTVDPKNKYQELINDIARDIRNQRRYRQRRKAELVKLQQTYAALNSKATFYGEQVDYYKSYIKTCLDN----LASKGKVSKKPREMKGKKSKKIS---LKYTAARLHEKGVLLEIED------------LQVNQFKNVIFEISPTEEVG-DFEVKAKFMG----VQMETFMLHYQDLLQLQYEG-VAVMKLFDR-AKVNVNLLIFLLNKKFYGK---", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q12280-1", "uniprot_id": "IQG1_YEAST", "id": "Q12280-1", "name": "Ras GTPase-activating-like protein IQG1", "aln": "------------------------------------------------MTAYSGSPSKPGNNNSYLNRYVENLGTNVTPPLR------PQSSSKINSSLNIASPSHLKTKTSASNSSATILSKKVESSVSKLKPSLPNKLVG-KYTVDLSNYSKIELRYYEFLCRVSEVKIWIEAVIEEALPSEIELCVGDSLRNGVFLAKLTQRINPDLTTVIFPAG--------DKLQFKHTQNINAFFGLVEHVGVPDSFRFELQDLYNKKNIPQVFETLHILISMINKKWPGKTPALTNVSGQISFTKEEIAACKKAWPR----IRDFKSLG-----------TNINTAPASPEEPKEKRSGLIKDFNKFERPN------------------IPVEEILITPRKNITDANCSDFSNTPSPYNEAPKMSNLDVVVEKRKFTPIEPSLLGPTPSLEYSPIKNKSLSYYSPTISKYLTYDTEFYTRRSRAREE------DLNYYQTFKYSPSHYSPMRRERMTEEQFLEKVVQLQNICRGVNTRFNLYIQKRLLNLFEQDILRFQACLRGNKFRVLSSMYLPIRRAKIDVPHVEAIQSRIKGSRIRYKYDKLKFTLSRFSCTVELLQAYCRSKLLKTTVNTKLNDIEISHYP-----LTKLQSYMRASYVRKKVMSLNTKLNDERESIMKFSAIIR---------GNVVRCSEDAILSAVHDVHKEN------------------------------------------------ISKLQSLIRGIFTR----------------------------------------------------------------------SCLASIIYSLGKE------NCNIIQLSACIRGNAVRHKVQSLFAPENNLSETVHDLQGLVRGILVR--YTLDLVDDIVEYNNLALFQAFSRGALVRESLDQKSSFYKRNVRSVIMIQSWIRKSLQRSAYLELLDCPNPSLWAVKKFVHLLNG-----------TATIEEVQNQLESCQASLDSENMKKERLLKSIRQQLNINGVLDKFGLLKDKDHELGISDSTIPKSK-------------YQKYEKLFYMLQVDPSYWKLLYLKEPEFVAKNVY--MTFGTVNQRMNDRERSYFTRFVCEMLQNAINEAPSIESFLDNRSQFWQTILQDFLR--RESPEFFSIIVPVLDYLSDP-VVDFESDPYKIYQEIHGFSSPQHCSP------------VDDASTKNKFIDNLRCLWHAIEMVAEIYTRKVHTIPVEIRYLCTKIFCYAADKN--IEEIDSLRAISSILVNVFVSEYLVNREYYGYKDSNVQ--------KNNQKIDILMKSLATVFEIKNFDGFLDPLNQYANEIKPHIKDVLYNVLVDPEYEQEGDRLIYLDMVSPSP----------------KLELLTEKVLEISGKFEEYLNEFPEADILHDILEKNLDNSSFPRS---GRVTLELDASAYRFLVSDD----KMRKIYDQVKRAFVYMMQIEDVDTNLYDLSISTILPQDEPNFANFLEQNPKIRDDPMIQKLKPLKYFTLKN-VTLKKIHELESTGTFCSSDNKLQNFLNDIANTIKNPNYAIDYVTQEIYITKETLTKISEMNHSLDIELSRLKKHVDHTIKDFQKAKDFSPVHKSKFGNFKNAVKKVQGRERSELQGMKFKWNTKQLYERGVLKTIRGEKLAELTVKVFGSSGPKFPDIIFKISTSDGSRFGIQMIDKRKGPDKRYSDDVDSFSFKDLIKTQVEPKIETWKLFHSNVVVNNSQLLHLIVSFFYKRNAL", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . . * . : *.: : : : **:**::.*.* *:** : * **. ** * *****:**** : :.*.:.:: . *:*:**:*: ::. ::.:*:*. * * *:*::**:*: : :* * : * * :* : :: *::.**:*** * : : *..:* : :::* : :*. ::* . * ::.** .:: :* ** *: . : . . .:* .*:: * :: *. :* . .::. :*. . .: * .:: : .: *:. : : *: :.. : :.*:: :: .:* : * :* * : * *: : : . .: . : : * :. * *: ::.. : :.:*. ::: :: * .:*:* ..::: :: : : : ::: :: .: * .:.* .: ** :: .:.*: :*.: :*::: * :: :* :* *:* *:: *.::.: : .:* : * :*.* ** **::.:* : :: :: :*. ** : * *. . :::. :*:::* .*: :: .::: ::..:* **::** . *. * *::. :*.: .*:******: *** . :.* * :. *: . :: :::::.::.*:.: *..*::* . * *.* : *::***:**.:*:* * :: *: :.:. : * * *:**. : *:. **: *:. . . : . . .:: .* * * . : .*:.**:. : * :::::** .**:. . ..* .. : . ..*.:: ..:* : . : . . . .*..** :*::.. : :* * : *: *..:* ::. :* : :. * .. :* .* ::: *: : . :..*. :*:* .: ::: .: . ** ::: : * *:*: : *: . * .. :.* *::: *. :..:: :. .* . * . .:. :.* : : .*: . *.* :.** :* ::::: :* * :: :. ::*.:. . :::. *** :*:* * .. .. ::*:: :* .** :: : * : *:: * : * *.*:.: :*: : : ::**: . ::.. * :. *:..: ::::*:: .::. :*:.: :*:*:*** *.. . :* ::**:*..:: .::: * * . :. : ::**:: * * : . ***. . ** . *:.*: . ** : ", "identical_positions": 268, "similar_positions": 553, "identity": "14.79%" }, { "cls_id": "homologset.agr.MGI:1352758", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3Z9J7-1", "uniprot_id": "D3Z9J7_RAT", "id": "D3Z9J7-1", "name": "non-specific serine/threonine protein kinase", "aln": "MEVVGDFEYSKRDLVGHGAFAVVFRGRHRQKTDWEVAIKSINKKNLSKSQILLGKEIKILKELQHENIVALYDVQELPNSVFLVMEYCNGGDLADYLQAKGTLSEDTIRVFLHQIAAAMRILHSKGIIHRDLKPQNILLSYASRRKSNVSGIRIKIADFGFARYLHSNTMAATLCGSPMYMAPEVIMSQHYDAKADLWSIGTVIYQCLVGKPPFQANSPQDLRMFYEKNRSLMPSIPRETSPYLANLLLGLLQRNQKDRMDFEAFFSHPFLEQV-PVRKSCPVPVPVYSGPGPGSSCSSSPPCRFASPPSLPDMQHIQEENLSSPPLGPPNYLQVSKDS-ASNSSKNSSCDTDDFVLVPHNISSDHSYDMPMGTAGRRASNEFFVCGGQCQP------TVSPHSETAPIPVPTQVRNYQRIEQNLISTASSGTNPHSSPRSAVVRRSNTSPMGFLRVGSCSPVPADTVQTGGRRLSTGSSRPYSPSPLVGTIPEQFSQCCCGHPQGHEARSRHSSG-SPVPQTQSPQSLLLGARLQSAPTLTDIYQNKQKLRKQHSDPVCPSLAGAGYSYSPQPSRPGSLGTSPTKHMGSSPRSSDWFFKTPLPTIIGSPTKTTAPFKIPKTQASSNLLALVTRHGPAESQSKDGNDPRQCSHCLLVQGSERHRSEQQ-SKAVFGRSVSTGKLSEQQHVKAPLGG--HQGSTDSLNTERPMDVAPAGACGVVLALPAGTAASARAVLFTVGSPPHSATAPTCTHMVLRTRTTSVGSNSSGGSLCSASGRVCVGSPPAPGFGSSPPGAEAAP-SLRYVPYGASPPSLEGLITFEAPELPEETLMEREHTDTLRHLNMMLMFTECVLDLTAVRGGNPELCTSAVSLYQIQESVVVDQISQLSKDWGRVEQLVLYMKAAQLLAASLHLAKAQIKSGKLSPSTAVKQVVKNLNERYKFCITMCKKLTEKLNRFFSDKQRFIDEINSVTAEKLIYNCAVEMVQSAALDEMFQQTEDIVQRYHKAALLLEGLSKILQDPADAESVHKYKCSIERRLSALCCSTAAV--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9QY01-1", "uniprot_id": "ULK2_MOUSE", "id": "Q9QY01-1", "name": "Serine/threonine-protein kinase ULK2", "aln": "MEVVGDFEYCKRDLVGHGAFAVVFRGRHRQKTDWEVAIKSINKKNLSKSQILLGKEIKILKELQHENIVALYDVQELPNSVFLVMEYCNGGDLADYLQAKGTLSEDTIRVFLHQIAAAMRILHSKGIIHRDLKPQNILLSYANRRKSNVSGIRIKIADFGFARYLHSNTMAATLCGSPMYMAPEVIMSQHYDAKADLWSIGTVIYQCLVGKPPFQANSPQDLRMFYEKNRSLMPSIPRETSPYLANLLLGLLQRNQKDRMDFEAFFSHPFLEQV-PVKKSCPVPVPVYSGPVPGSSCSSSPSCRFASPPSLPDMQHIQEENLSSPPLGPPNYLQVSKDS-ASNSSKNSSCDTDDFVLVPHNISSDHSYDMPMGTTARRASNEFFMCGGQCQP------TVSPHSETAPIPVPTQVRNYQRIEQNLISTASSGTNPHGSPRSAVVRRSNTSPMGFLRVGSCSPVPGDTVQTGGRRLSTGSSRPYSPSPLVGTIPEQFSQCCCGHPQGHEARSRHSSG-SPVPQTQAPQSLLLGARLQSAPTLTDIYQNKQKLRKQHSDPVCPSHAGAGYSYSPQPSRPGSLGTSPTKHTGSSPRNSDWFFKTPLPTIIGSPTKTTAPFKIPKTQASSNLLALVTRHGPAESQSKDGNDPRECSHCLSVQGSERHRSEQQQSKAVFGRSVSTGKLSEQQ-VKAPLGG--HQGSTDSLNTERPMDVAPAGACGVMLALPAGTAASARAVLFTVGSPPHSATAPTCTHMVLRTRTTSVGSSSSGGSLCSASGRVCVGSPPGPGLGSSPPGAEGAP-SLRYVPYGASPPSLEGLITFEAPELPEETLMEREHTDTLRHLNMMLMFTECVLDLTAVRGGNPELCTSAVSLYQIQESVVVDQISQLSKDWGRVEQLVLYMKAAQLLAASLHLAKAQVKSGKLSPSMAVKQVVKNLNERYKFCITMCKKLTEKLNRFFSDKQRFIDEINSVTAEKLIYNCAVEMVQSAALDEMFQQTEDIVYRYHKAALLLEGLSKILQDPTDVENVHKYKCSIERRLSALCCSTATV--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8IYT8-1", "uniprot_id": "ULK2_HUMAN", "id": "Q8IYT8-1", "name": "Serine/threonine-protein kinase ULK2", "aln": "MEVVGDFEYSKRDLVGHGAFAVVFRGRHRQKTDWEVAIKSINKKNLSKSQILLGKEIKILKELQHENIVALYDVQELPNSVFLVMEYCNGGDLADYLQAKGTLSEDTIRVFLHQIAAAMRILHSKGIIHRDLKPQNILLSYANRRKSSVSGIRIKIADFGFARYLHSNMMAATLCGSPMYMAPEVIMSQHYDAKADLWSIGTVIYQCLVGKPPFQANSPQDLRMFYEKNRSLMPSIPRETSPYLANLLLGLLQRNQKDRMDFEAFFSHPFLEQG-PVKKSCPVPVPMYSGSVSGSSCGSSPSCRFASPPSLPDMQHIQEENLSSPPLGPPNYLQVSKDS-ASTSSKNSSCDTDDFVLVPHNISSDHSCDMPVGTAGRRASNEFLVCGGQCQP------TVSPHSETAPIPVPTQIRNYQRIEQNLTSTASSGTNVHGSPRSAVVRRSNTSPMGFLRPGSCSPVPADTAQTVGRRLSTGSSRPYSPSPLVGTIPEQFSQCCCGHPQGHDSRSRNSSG-SPVPQAQSPQSLLSGARLQSAPTLTDIYQNKQKLRKQHSDPVCPSHTGAGYSYSPQPSRPGSLGTSPTKHLGSSPRSSDWFFKTPLPTIIGSPTKTTAPFKIPKTQASSNLLALVTRHGPAEEQSKDGNEPRECAHCLLVQGSERQRAEQQ-SKAVFGRSVSTGKLSDQQ-GKTPICR--HQGSTDSLNTERPMDIAPAGACGGVLAPPAGTAASSKAVLFTVGSPPHSAAAPTCTHMFLRTRTTSVGPSNSGGSLCAMSGRVCVGSPPGPGFGSSPPGAEAAP-SLRYVPYGASPPSLEGLITFEAPELPEETLMEREHTDTLRHLNVMLMFTECVLDLTAMRGGNPELCTSAVSLYQIQESVVVDQISQLSKDWGRVEQLVLYMKAAQLLAASLHLAKAQIKSGKLSPSTAVKQVVKNLNERYKFCITMCKKLTEKLNRFFSDKQRFIDEINSVTAEKLIYNCAVEMVQSAALDEMFQQTEDIVYRYHKAALLLEGLSRILQDPADIENVHKYKCSIERRLSALCHSTATV--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0ACD6B739-1", "uniprot_id": "A0ACD6B739_DANRE", "id": "A0ACD6B739-1", "name": "non-specific serine/threonine protein kinase", "aln": "METVGDFEYSRKDLIGHGAFAVVFKGRHKKKTDWEVAIKSINKKNLSKSQILLGKEIKILKELQHENIVALYDVQETPSSVFLVMEYCNGGDLADYLQAKGTLREDTLRVFLQQIAAAMRILNSKGIIHRDLKPQNILLSYTGRKKSSINGIRIKIADFGFARYLQSNMMAATLCGSPMYMAPEVIMSQNYDAKADLWSIGTVIYQCLVGKPPFQANSPQDLRMFYEKNKSLVPNIPRETSPQLEDLLLGLLQRNQKDRIDFDTFFSHPFLEPISTIKKSCPVPVPSCSGLVSDSTCGSSPSCRYVSPPSLPDMQTLPEDVLSSPPLGPPNYLQLSKESGGSTSSKNSSCDTDDFVLVPH-LSGEQSYDLPMGAVGRRPSSEFLLCGGSPQPSTGQTPMVSPRSETTPIPVPSQVRNYQRIKQNLSSSPT--TTLYGSPRSGTVRRSNTSPMGFPKMVSASPSPADTVQTVGRRLSTGSSRPYSPSPLVGTIPEQLGHCCCGHPQSHEPRSRSSSGGSPVPSSQ-----LLGARLQSAPTLTDIYQSKQKLHKQLSDPVHPTSSAYPSNHSPQLGRPANLGTSPTKHLGSSPRTSDWLTKSPLPTIIGSPTKVTAPFKIPKTQASCNLMALADSPIPN-KTLMDGRE--LCAHHCTAYPSSRQPAPEA-SKTSFGRSVSAGRLSEPP-VRITLGGQPYQGSTDSLNTERPMDTAPAGMC----ALAAG-GGSPRTVVFTVGSPPSSSTPPTCSHLASRPRATSVGSNSSAGSLCSTSGKVYMGSPPGMTIGSSPPGAEAGPSSLRYVPYGTSPPSLDGFITFEAPELPEETLMEREHTDTLMYLRMMLSFTDCVLEIAALRAGGPDLGASAASLYPPQDSVVVDQISQLSREWGQVEQLVLYMKAAQLLASSLHLAKAQIKSAKLNPSTAVKQVVKSLNERYKSCISLCRRLTDKLNHFFSDKQRFVDEINSVTAEKLIYNHAVEMVQSAALDEMFQQTEDIAYRYNKASMLLEGLTKILQDPADIENVIKYKASVDRRISALCYCTVTLYE", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "**.******.::**:*********:***::********************************************** *.************************ ***:****:*********:******************:.*:**.:.***************:** ********************:***************************************:**:*.******* * :*************:**::******** .::******** ** ..*:*.***.**:.********* : *: *************:**:* .*.***************** :*.::* *:*:*:..**.*.**::***. ** ***:***:*****:*:******:*** *:.: *. :.****..*********** : *.** *.**.** ************************:.:*******.*:.*** *** ****.:* * ***************.****:** **** *: :. .:*** .**..******** *****.***: *:***********.************.**:**. * . **.: *:* . *.*: : : **: ******:*:**: : .: :************** **** * * .** ..*.::*:******* *::.***:*: *.*:****...*.****: **:* :****. :********..* ********:*****:*:********************** :*.:** **:***:::*:*.*.*:* :**.*** *:***********::**:***************:********:**.**.** *******.****** **::*::**:***:********:************** ********************. **:**::*****::*****:* *.* ***.*::**:**** .*.:: ", "identical_positions": 750, "similar_positions": 189, "identity": "71.29%" }, { "cls_id": "homologset.agr.MGI:1352759", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9QYK7-1", "uniprot_id": "RNF11_MOUSE", "id": "Q9QYK7-1", "name": "RING finger protein 11", "aln": "MGNCLKSPTSDDISLLHESQSDRASFGEGTEPDQEPPPPYQEQVPVPIYHPTPSQTRLATQLTEEEQIRIAQRIGLIQHLPKGVYDPGRDGSEKKIRECVICMMDFVYGDPIRFLPCMHIYHLDCIDDWLMRSFTCPSCMEPVDAALLSSYETN", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9Y3C5-1", "uniprot_id": "RNF11_HUMAN", "id": "Q9Y3C5-1", "name": "RING finger protein 11", "aln": "MGNCLKSPTSDDISLLHESQSDRASFGEGTEPDQEPPPPYQEQVPVPVYHPTPSQTRLATQLTEEEQIRIAQRIGLIQHLPKGVYDPGRDGSEKKIRECVICMMDFVYGDPIRFLPCMHIYHLDCIDDWLMRSFTCPSCMEPVDAALLSSYETN", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0ABK0LKR9-1", "uniprot_id": "A0ABK0LKR9_RAT", "id": "A0ABK0LKR9-1", "name": "RING finger protein 11", "aln": "MGNCLKSPTSDDISLLHESQSDRASFGEGTEPDQEPPPPYQEQVPVPVYHPTPSQTRLATQLTEEEQIRIAQRIGLIQHLPKGVYDPGRDGSEKKIRECVICMMDFVYGDPIRFLPCMHIYHLDCIDDWLMRSFTCPSCMEPVDAALLSSYETN", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0A8I6AJA6-1", "uniprot_id": "A0A8I6AJA6_RAT", "id": "A0A8I6AJA6-1", "name": "RING finger protein 11", "aln": "MGNCLKSPTSDDISLLHESQSDRASFGEGTEPDQEPPPPYQEQVPVPVYHPTPSQARLATQLTEEEQIRIAQRIGLIQHLPKGGYDPGRDGSEKKIRECVICMMDFVYGDPIRFLPCMHIYHLDCIDDWLMRSFTCPSCMEPVDAALLSSYETN", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "B0V2S5-1", "uniprot_id": "B0V2S5_DANRE", "id": "B0V2S5-1", "name": "RING finger protein 11", "aln": "MGNCLKSPTSDDISLLHESQSDRASFGDANDPDQEPPPPYQEQIHVPVYHPTPSQARLATQLTEEEQVRIAQRIGLIQHLPKGVYDPGSDGTEKKIRECVICMMDFVYGDPIRFLPCMHIYHLDCIDDWLMRSFTCPSCMEPVDAALLSSYETN", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "***************************:..:************: **:*******:***********:*************** **** **:**************************************************************", "identical_positions": 142, "similar_positions": 9, "identity": "92.21%" }, { "cls_id": "homologset.agr.MGI:1352760", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q923W4-1", "uniprot_id": "HDGR3_RAT", "id": "Q923W4-1", "name": "Hepatoma-derived growth factor-related protein 3", "aln": "MARPRPRE-YKAGDLVFAKMKGYPHWPARIDELPEGAVKPPANKYPIFFFGTHETAFLGPKDLFPYKEYKDKFG--KSNKRKGFNEGLWEIE-------NNPGVKFTGYQTIQQQSSSE------------------------------------------TEGEGGNTADASSEEEGDRVE-DGKGKRKNEKGGSKRKKSYTSKKSSKQSR----KSPGDEDDK------------------------DCKEEENKSSSEGGDAGND-TRNTTSDLQKAGEGT-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9JMG7-1", "uniprot_id": "HDGR3_MOUSE", "id": "Q9JMG7-1", "name": "Hepatoma-derived growth factor-related protein 3", "aln": "MARPRPRE-YKAGDLVFAKMKGYPHWPARIDELPEGAVKPPANKYPIFFFGTHETAFLGPKDLFPYKEYKDKFG--KSNKRKGFNEGLWEIE-------NNPGVKFTGYQTIQQQSSSE------------------------------------------TEGEGGNTADASSEEEGDRVE-DGKGKRKNEKGGSKRKKSYTSKKSSKQSR----KSPGDEDDK------------------------DCKEEENKSSSEGGDAGND-TRNTTADLQKAGEGT-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9Y3E1-1", "uniprot_id": "HDGR3_HUMAN", "id": "Q9Y3E1-1", "name": "Hepatoma-derived growth factor-related protein 3", "aln": "MARPRPRE-YKAGDLVFAKMKGYPHWPARIDELPEGAVKPPANKYPIFFFGTHETAFLGPKDLFPYKEYKDKFG--KSNKRKGFNEGLWEIE-------NNPGVKFTGYQAIQQQSSSE------------------------------------------TEGEGGNTADASSEEEGDRVEEDGKGKRKNEKAGSKRKKSYTSKKSSKQSR----KSPGDEDDK------------------------DCKEEENKSSSEGGDAGND-TRNTTSDLQKTSEGT-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VAA9-1", "uniprot_id": "Q9VAA9_DROME", "id": "Q9VAA9-1", "name": "", "aln": "MGKEKAAASYSIGDLVFAKVKGYPPWPAKITKSNN------NKKYNVYFYGTGETANIKLEDLFPYASNKERFATEKIMKRAKFIEAIDQIESALRGEDSAPIDLLDGAEPVAPPTTGDGVKTEEPKPEPGPEPATAAPVAAAAEKPKKSGTRKTKAPPRHVDGDSEAGAELAPPPAKRRVPTEGLATAAAIPAAPAAATPTSSKKSVKKSKPTAAVTPIQKRSRPVNNIRNEMLMVYMPTAKCLGIVINYKKPESFESAAAEEAWMENARKEALELKLKLESGQINPESMPDRIVVEPTRSEIPKQEALRFIEELIEHEDALFMERDFIQLSQQLRECLGLRRANVGKCLEILEQFKEVEFTKLMLLRNPECVDIMRRLRRYVGNLELWKMDLSDEVEFKERAQTIRKVSSGIYDGFKSLFNPEPESEDNFWIDFCEKVKIYKTYTKNINENLRVGMNERGYNSLVLAKEAAASAGSAPQ", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*.: :. *. *******:**** ***:* : : :** ::*:** *** : :***** . *::*. * ** * *.: :** . * : * :.: ::.: .:*:. *: :. ** :* .. ... .. :**** *:*: :* :: .: : *: *. .*: . :* : :*: : :*: *. ", "identical_positions": 60, "similar_positions": 68, "identity": "12.47%" }, { "cls_id": "homologset.agr.MGI:1352762", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q96GD3-1", "uniprot_id": "SCMH1_HUMAN", "id": "Q96GD3-1", "name": "Polycomb protein SCMH1", "aln": "---------------------------------------------------------------------------------------------------------------------------MLVCYSVLACEILWDLPCSIMGSPLG------------------------HFTWDKYLKETCSVPAPVHCFKQSYTPPSNEFKISMKLEAQDPRNTTSTCIATVVGLTGARLRLRLDGSDNKNDFWRLVDSAEIQPIGNCEKNGGMLQPPLGFRLNASSWPMFLLKTLNGAEMAPIRIFHKEPPSPSHNFFKMGMKLEAVDRKNPHFICPATIGEVRGSEVLVTFDGWRGAFDYWCRFDSRDIFPVGWCSLTGDNLQPPGTKVVIPKNPYPASDVNT------EKPSIHSSTKTVLEHQPGQRGRKP----------------------------GKKRGRTPKTLISHPISAPSKTAEPLKFPKKRGPKPGSKRKPRT--LLNPPPASPTTSTP----------EPDTSTVPQDAATIPSSAMQAPTVCIYLNKNGSTGPHLDKKKVQQLPDHFGPARASVVLQQAVQACIDCAYHQKTVFSFLK----QGHGGEVISAVFDREQHTLNLPAVNSITYVLRFLEKLCHNLRSDNLFGNQPFT------------------QTHLSLTAIEYSHSHDRYLPGETFVLGNSLAR-----SLEPHSDSMDSASNPTNLVSTSQ-----RHRPLLSSCG----LPPSTASAVRRLCSRGVLKGS-------NERRDMESFWKLNRSPGSDRYLESRDASRLSGRDPSSWTVEDVMQFVREADPQ-LGPHADLFRKHEIDGKALLLLRSDMMMKYMGLKLGPALKLSYHIDRLKQ----------------------------GKF--------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8K214-1", "uniprot_id": "SCMH1_MOUSE", "id": "Q8K214-1", "name": "Polycomb protein SCMH1", "aln": "---------------------------------------------------------------------------------------------------------------------------MLVCYSVLACESLWDLPCSIMGSPLG------------------------HFTWDKYLKETCSVPAPVHCFKQSYTPPSNEFKISMKLEAQDPRNTTSTCIATVVGLTGARLRLRLDGSDNKNDFWRLVDSSEIQPIGNCEKNGGMLQPPLGFRLNASSWPMFLLKTLNGAEMAPIKIFHKEPPSPSHNFFKMGMKLEAVDRKNPHFICPATIGEVRGAEVLVTFDGWRGAFDYWCRFDSRDIFPVGWCSLTGDNLQPPGTKVVIPKNPSPSSDVST------EKPSIHS-TKTVLEHQPGQRGRKP----------------------------GKKRGRTPKILIPHPTSTPSKSAEPLKFPKKRGPKPGSKRKPRT--LLSPPPTSPTTSTP----------EPDTSTVPQDAATVPSSAMQAPTVCIYLNKSGSTGPHLDKKKIQQLPDHFGPARASVVLQQAVQACIDCAYHQKTVFSFLK----QGHGGEVISAVFDREQHTLNLPAVNSITYVLRFLEKLCHNLRSDNLFGNQPFT------------------QTHLSLTATEYNHNHDRYLPGETFVLGNSLAR-----SLETHSDLMDSALKPANLVSTSQNLRTPGYRPLLPSCG----LPLSTVSAVRRLCSKGVLKGK-------KERRDVESFWKLNHSPGSDRHLESRDPPRLSGRDPSSWTVEDVMQFVREADPQ-LGSHADLFRKHEIDGKALLLLRSDMMMKYMGLKLGPALKLSFHIDRLKQVFWKRETILWSREGLSREVWPISEDTALGHFFSGMDKVFGSLSKR", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8M3B461-1", "uniprot_id": "A0A8M3B461_DANRE", "id": "A0A8M3B461-1", "name": "", "aln": "---------------------------------------------------------------------------------------------------------------------------MGKTHQKDKKHHKEKSGRNNEDSQPSQ-------------------KLTEAFSWEMYLRETSSCPASPSCFRQSRVPPANDFRVGMKVEACDPRNASSWCIATVMGLMGVRLRLRLDGSDSTNDFWRLVDAADIQPIGTCEKSGDMLQPPLGFRMNASSWPMFLLKTLSGAEMAPSSAFKKEPPRPTQNFFKAGMKLEAVDRKNPYLICPATIGEVRGDKIFIMFDGWRGAFDYWCQFDSRDIFPVGWCQLTNHSLQPPGNCFTIPKTLLPSVSRPSPSWRPMQSPYRLPHPLPPLPVRKGVRGRRPKSQT-----------IAMLKAAAEAAAAGNSPSQNGQSQPTSAHKSPISSPLTPKPYKKRGPKPGSKRKPKVPHSLSSPILSSSVSDG----------RLSSLQTTRDSGVVS-------TVCVYVNKHGNSGPHLDRKLLLQLPDHFGPGPVNTVLQHAVQACVDCAFQPKALFSFLQS---QSDGGEIIRVRSEGGIHYVKLPTASSASFVLRFLETLCHHLQCDNLFSSQPFSPLTSSTHTPYERSKSVKEETSEALSVARGTRRFNRDSSAYSTALSPKLQRTEALPSDETIAHAENGASTEQQFLEESMDSASKSVAPRPPAHRSTSEFHTPTGSSPHYPSHPPLLRGLSSNPAEPRTHRRVEGRLSASSTTGPDHQATEKDPSKTSNKSPSSWSIEEVMQFVRDADPQALGPHAELFRKHEIDGKALMLLRSDMIMKYMGLKLGPALKLCHHIEKLKQTK-------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VHA0-1", "uniprot_id": "SCM_DROME", "id": "Q9VHA0-1", "name": "Polycomb protein Scm", "aln": "MSGGRDSSTSSGSNSAAPGASTNATSSASASASSTSTSASPGSTTSPASTQRQRGRPAKRATCTWCGEGKLPLQYVLPTQTGKKEFCSETCIAEFRKAYSKGACTQCDNVIRDGAPNKEFCSIMCMNKHQKKNCSTRHSGGSASGKGLAESERKLLASGAPAPTGPFQYESFHVFDWDAYLEETGSEAAPAKCFKQAQNPPNNDFKIGMKLEALDPRNVTSTCIATVVGVLGSRLRLRLDGSDSQNDFWRLVDSTEIHAIGHCEKNGGMLQPPLGFRMNASSWPGYLCKILNNAMVAPEEIFQPEPPEPEENLFKVGQKLEAVDKKNPQLICCATVDAIKDDQIHVTFDGWRGAFDYWCNYRSRDIFPAGWCARSCHPMQPPGHKSRMDSSSSKQRCPRPRYTVVAESEAMVPASPATAHFHPNCKGGPFINNSKLPCMVTGPTYQTLAKLCLQEVLAASTDTQQLSKLLFALEGDVHIVTAAGKNFTVKIPSPMRMKDDESLAQFIETLCTTCRACANLISLVHETEECKKCANSRKRQLTQSATPPSSPVLADKRNRQSNSATTSPSEKIIKQELAVKSPVESKSKTSTNNGKEPASQQNSNHSLNNNNNSASKSSNKVVIKSEPNGANAQTSSTTQALRKVRFQHHANTNTNSSATNGNQDTS-----------------QTTHVSTSHCSSSSTSSSTSLAGGSANTSTIGKYLAPLVAEVHPEQANVKPSNSYYKSPTTLSSSASLPTSVSTPFTGCQSASSTALAAGGVTAAKAATAP------AGAAATAGASPSYTAITSPVSTPTSALANSHLRSQPIDWTIEEVIQYIESNDNS-LAVHGDLFRKHEIDGKALLLLNSEMMMKYMGLKLGPALKICNLVNKVNGRRNNLAL--------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * . . .. . * *: **.** * .*. **:*: ** *:*::.**:** ****.:* *****:*: * **********. ********:::*:.** ***.*.*********:****** :* * *..* :** *: *** * .*:** * ******:*** :** **:. ::. :: : ************.: ******.*** : . :**** : .. . :. . . . : . :* ... : . . . * . : *.* :. . : . :. : . .. .:. .* .: .... . . : . .. : :.: : * : :: .*: : ....: : : : .:... :** . : ... ..* : * : : . . . . .: : * .. : . . : . .: .* : . . . . ... . . .* .*::*:*:*::.. * . *. *.:************:**.*:*:*************:. ::::: ", "identical_positions": 175, "similar_positions": 188, "identity": "18.64%" }, { "cls_id": "homologset.agr.MGI:1353418", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O35621-1", "uniprot_id": "PMM1_MOUSE", "id": "O35621-1", "name": "Phosphomannomutase 1", "aln": "MAVAVEGARRKERILCLFDVDGTLTPARQKIDPEVSAFL-QKLRSRVQIGVVGGSDYSKIAEQLGEGDEVIEKFDYVFAENGTVQYKHGRLLSKQTIQNHLGEELLQDLINFCLSYMALLRLPKKRGTFIEFRNGMLNVSPIGRSCTLEERIEFSELDKKEKIREKFVEALKTEFAGKGLRFSRGGMISFDVFPEGWDKRYCLDSLDED-SFDIIHFFGNETSPGGNDFEIYADPRTVGHSVVSPQDTVQRCRELFFPETAHEA", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q92871-1", "uniprot_id": "PMM1_HUMAN", "id": "Q92871-1", "name": "Phosphomannomutase 1", "aln": "MAVTAQAARRKERVLCLFDVDGTLTPARQKIDPEVAAFL-QKLRSRVQIGVVGGSDYCKIAEQLGDGDEVIEKFDYVFAENGTVQYKHGRLLSKQTIQNHLGEELLQDLINFCLSYMALLRLPKKRGTFIEFRNGMLNISPIGRSCTLEERIEFSELDKKEKIREKFVEALKTEFAGKGLRFSRGGMISFDVFPEGWDKRYCLDSLDQD-SFDTIHFFGNETSPGGNDFEIFADPRTVGHSVVSPQDTVQRCREIFFPETAHEA", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P07283-1", "uniprot_id": "PMM_YEAST", "id": "P07283-1", "name": "Phosphomannomutase", "aln": "MSIAEFAYKEKPETLVLFDVDGTLTPARLTVSEEVRKTL-AKLRNKCCIGFVGGSDLSKQLEQLG--PNVLDEFDYSFSENGLTAYRLGKELASQSFINWLGEEKYNKLAVFILRYLSEIDLPKRRGTFLEFRNGMINVSPIGRNASTEERNEFERYDKEHQIRAKFVEALKKEFPDYGLTFSIGGQISFDVFPAGWDKTYCLQHVEKD-GFKEIHFFGDKTMVGGNDYEIFVDERTIGHSVQSPDDTVKILTELFNL------", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "Q9VTZ6-1", "uniprot_id": "PMM_DROME", "id": "Q9VTZ6-1", "name": "Phosphomannomutase", "aln": "---MTTAALKRDEILLLFDVDGTLTMPRSVVTPEFEEFFYSRVKPRATIGIVGGSDLEKMFEQLN-GRKILNEFDFIFPENGLVQIEGGKEVGKQNIIMHLGEETVKRFINFVLRYLSELDVPIKRGTFIEFRNGMMNVCPIGRQCTREERNMFAEYDIEHKVREKMIKDLKQEFADVDLTYSIGGQISFDVFPHGWDKTYCLRHIEAHYKFKEIHFFGDKTEPGGNDYEIYSDPRTISHRVYTPKDTQRILTEILEL------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . .: . * ********* .* : *. : ::: : **.***** * ***. :::::**: *.*** . . *: :..*.: **** : : * * *:: : :* :****:******:*:.****..: *** * . * :.::* *::: ** **.. .* :* ** ******* **** *** :: . *. *****::* ****:**: * **:.* * :*.** : *:: ", "identical_positions": 105, "similar_positions": 70, "identity": "39.77%" }, { "cls_id": "homologset.agr.MGI:1353419", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZLP2-1", "uniprot_id": "D3ZLP2_RAT", "id": "D3ZLP2-1", "name": "RING finger protein 17", "aln": "MAAEASSTG--LASCHLAGSK--SGAPGASGCQCTRCGRKASFASGHHHEYPCGHAFCELCLLAP-QEYTTSKCTDCEVRTTVTMNQGHYPVDGFIKEDSS----------VEALPPKMVNNCSSGLEKTVDQLIINLEHSSSIHRNVSSPSAVMSET---EEIDEALKIAGCNSEQLSNAIKMLDS-TQDQTRQE--------TGSLREVVEKQFDTLIASLDSRKKSLCEELVRRTDDYLSKLVTVKSYIEEKKSDLD-------------AAMKIAKELKSAPSLRTYCDLTQIIRTLKLNFESELSQVSSIIPRNPPRLNINCSEVICMFNSMGKIEFEDSTKCHPQENEVGQNVQKKFNSKKEL-CCDVYSSLEKKRVDTVVLADEAPVPPLQAETPDRHLEGENKQPQKEVLVVASPKTVAVLPQLGSSPDVIIEEIIEEN---LESCFTDEPIETPRYPKKPPQKELSAPVASKAGCPELVFVSHVTHPCHFYVRKYSQIKDAAMLEKKMKQVCSKSLHLDPSD---TLELGARIFVNSIKNRMWCRGIITEIIPTKTKNVRKPCSPTKFSVCEISLIQIFMVDFGNSEVLIITGVGDTHVGPEHVGEQHITLSDFCLLVRKSEP-YSEELLKDIPHLAHLCSLKDIVPYNSSEGWEKEAKVEFLKMVNKKAVLMKVFGEEDDILIVDLQKPPTNKISSDMPVSLRDALVFMELARFRSQSLRSHGENNTALCYRPPALPEEMTEVSVMVCHINSPTDFYLQLMEN-LDFLSLLKTIEEFYKGEDGEN-LEILCPLQNQACVAKFEDGIWYRAKVIGLPGHREVEVKYVDFGNTAKITLKDMRKIKDEFLEPPEKAIKCKLAFIEPSKR--SHWSKKAKEKFEEKTQDKFVTCSVIKILENG-VLLVELFDSR-APGTSAVSINEQLVKEGLASYEAGYTLKDNSKKHLEVWDPSPEEIISSEINSLSPLSVNSLANESFQSLYNKELPVSICNVLSPEKIYVQWLLTENLLTSLEEKMVAAYEHSEW---KPVKWECDMHCAVKIPAKSQWRRGQIIRMVTDTLVEVLLYDVG-----------IELVVNIHCLRELQENLKTMGRLSLECSLVDIRPTGGSDKWTATACDCLSLYLTGAIATIILQ----ENSTTWPLPVKIFCRD-----EKGERVDVSKYLIKKGLALRDRRVSKSSNSHSP-EKSLEIPLEQGDS----------------------VVTKCFQINFDTNKKIADKVNEHKVPESKEKYSESRTNGFYKPPAVPNTSSFEAIVSCIGDDGTIFVVPKLSEFELIKMMDEIQSNLKCLG-----LLEPYFWKKGEPCAVR-GSDTLWYRGKVMEVVG--GTIRVQYLDHGFTEKIPQCHLYPILLYPDTPQFCIPCQLYQTLPCVCVCVHYTQVGNVWQPDAIELLQELLSKREVDIHIMELPDHPWGKLSVHLYFDGMSLSYFMAYH-------------------------KYCIFEHTEEIFKEKPRG-QNKKYEDENWKIRFEDLLLPEMEAPILPPYLSSLLPPPEELYAVQVKHIVSPD---------------------------------EVYICLDSVESCTQLNNHGDTDDSGVSWEPESESLEEALQRLNKN------------------------------------------------------------VETFPPLTDFSSEMPCLAEYA-DGLWYRAKIVSIKEFNP---LSVLVLFVDYGSTEKLTINRLRQIPIQLMQYPAQAIKVLLAGFKPPLSDSGK---TRIPYCPRWSMEALWTMIDCLQGKQLYASSVAQAPEQIVTLYEDEQYPVHMSLVEMGLADKDE", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q99MV7-1", "uniprot_id": "RNF17_MOUSE", "id": "Q99MV7-1", "name": "RING finger protein 17", "aln": "MAAEASSTG--LASCHLVESK--SGAQGASGCQCTRCGRKVSVASGDHHKFPCGHAFCELCLLAP-QEYTTSKCTDCEVHTTVSMNQGHYPVDGFIEEDSS----------LEALPPKMVNNCSSDLEKTVDQLINDLEHSSSIHRNVSNPSAVMSET---EEIDEALKIAGCNFEQLSNAIKMLDS-TQDQTRQE--------THSLTEAVEKQFDTLLASLDSRKKSLCEELIRRTDDYLSKLVTVKSYIEEKKSDLD-------------AAMKIAKELRSAPSLRTYCDLTQIIRTLKLTFESELSQVSSIIPRNTPRLDINCSEAICMFSSMGKIEFEDSTKCYPQENEDGQNVQKKFNNRKEL-CCDVYSSLEKKKVDAAVLTDETPEPPLQAEAPDRHLEGKKKQPTKEMVVVTSPKTIAVLPQLGSSPDVIIEEIIEEN---LESCFTDDPIETSGYPKKPPQKEQSAPVGSKAGCPELVFVSHVIHPCHFYVRKYSQIKDATILEKKMKQVCNRSLHLDPSD---ILELGARIFVNSIKNRMWCRGIITEIIPSKTKNIRKPCSPTKFSVCEISLIQIFMVDFGNSEVLIITGVGDTHEGPEHDGEQHITLSDFCLLLMKSEP-YSEELLKDIPHLAHLCSLKDIVPYNSTEGWEKEAKVEFLKMVNKKAVLMKVFGEEDDVLIVDLQKPPTNKISSDMPVSLRDALVFMELARFRSQSPRSHSEKNTTLCYHPPILPEEMTEVSVMVCHINSPTDFYLQLMEN-LDFLSLLKTIEEFYKGEDGEN-LEILCPLQNQACVAKFEDGIWYRAKVIGLPGHREVEVKYVDFGNTAKITLKDMRKIKDEFLEPPEKAIKCKLAYVEPSKK--SQWSKKAKEKFEEKTQDKFVTCSVIKILENN-VLLVELFDSR-APGKSAVSINDQLVKEGLASYEAGYTLKDNSKKHLEVWDPSPEEIITSEINNLSPLSVKSLPNENFQSLYNKELPVNICNVISPEKIYVQWLLTENLLNSLEEKMVAAYEHSEW---KPVKWECDMHCAVKVPAKNQWRRGQILRMVTDKLVEVLLYDVG-----------VELVVNIHCLRELQENLKTMGRLSLECSLVDIRPTGGSDKWTATACDCLSLHLTGAIATIILQ----ESNTTWPLPVKIFCRD-----EKGERVDVSKYLIKKGLALRERRVSKSSNSHSP-EKSLEIPLEQGDS----------------------VVTKCFKINFDTNKKIADKVNEHKVPDSKGKKSESRSTGCYRPPAVPNTSSFEAIVTCIGDDGTIFVVPKLSEFELIKMMDEIQSNLKCLG-----LLEPYSWKKGEPCAVR-GSDTLWYRGKVMEVVG--GTIRVQYLDHGFTEKIPQCHLYPILLYPDTPQFCIPCQLYQTLP----------VGNTWQPDAIELLQELLSKREVDIHIMELPNNSWGKLSVHLYFDGMSLSHFMAHH-------------------------KYCIFEHTEEIFKEKPRG-QNKKYEDENWKIRFEDLLLPEMEAPVLPPYLSSLLPPPEELFAVQVKHIVSPD---------------------------------EMYICLDSEDSYTQFNHHGDTDDSGVSWESESENLEEALQRFNKN------------------------------------------------------------VETFPPLTDFSSEMPCLAEYA-DGLWYRAKIISIKEFNP---LSVLVLFVDYGCTEKLTINRLRQIPVQLMQYPAQAIKVLLAGFKPPLSDSGK---TRIPYCPKWSMEALWTMIDCLQGKQLYASSVAQAPEQIVTLYEDEQYPVHMSLVEMGLADKDE", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9BXT8-3", "uniprot_id": "RNF17_HUMAN", "id": "Q9BXT8-3", "name": "RING finger protein 17", "aln": "MAAEASKTGPSRSSYQRMGRK--SQPWGAAEIQCTRCGRRVSRSSGHHCELQCGHAFCELCLLMT-EECTTIICPDCEVATAVNTRQRYYPMAGYIKEDSI----------MEKLQPKTIKNCSQDFKKTADQLTTGLERSASTDKTLLNSSAVMLDTNTAEEIDEALNTAHHSFEQLSIAGKALEH-MQKQTIEE--------RERVIEVVEKQFDQLLAFFDSRKKNLCEEFARTTDDYLSNLIKAKSYIEEKKNNLN-------------AAMNIARALQLSPSLRTYCDLNQIIRTLQLTSDSELAQVSSPQLRNPPRLSVNCSEIICMFNNMGKIEFRDSTKCYPQENEIRQNVQKKYNNKKELSCYDTYPPLEKKKVDMSVLTSEAPPPPLQPETNDVHLEAKNFQPQKD-VATASPKTIAVLPQMGSSPDVIIEEIIEDN---VES------------------------------SAELVFVSHVIDPCHFYIRKYSQIKDAKVLEKKVNEFCNRSSHLDPSD---ILELGARIFVSSIKNGMWCRGTITELIPIEGRNTRKPCSPTRLFVHEVALIQIFMVDFGNSEVLIVTGVVDTHVRPEHSAKQHIALNDLCLVLRKSEP-YTEGLLKDIQPLAQPCSLKDIVPQNSNEGWEEEAKVEFLKMVNNKAVSMKVFREEDGVLIVDLQKPPPNKISSDMPVSLRDALVFMELAKFKSQSLRSHFEKNTTLHYHPPILPKEMTDVSVTVCHINSPGDFYLQLIEG-LDILFLLKTIEEFYKSEDGEN-LEILCPVQDQACVAKFEDGIWYRAKVIGLPGHQEVEVKYVDFGNTAKITIKDVRKIKDEFLNAPEKAIKCKLAYIEPYKRT-MQWSKEAKEKFEEKAQDKFMTCSVIKILEDN-VLLVELFDSLGAPEMTTTSINDQLVKEGLASYEIGYILKDNSQKHIEVWDPSPEEIISNEVHNLNPVSAKSLPNENFQSLYNKELPVHICNVISPEKIYVQWLLTENLLNSLEEKMIAAYENSKW---EPVKWENDMHCAVKIQDKNQWRRGQIIRMVTDTLVEVLLYDVG-----------VELVVNVDCLRKLEENLKTMGRLSLECSLVDIRPAGGSDKWTATACDCLSLYLTGAVATIILQVDSEENNTTWPLPVKIFCRD-----EKGERVDVSKYLIKKGLALRERRINNLDNSHSLSEKSLEVPLEQEDS----------------------VVTNCIKTNFDPDKKTADIISEQKVSEFQEKILEPRTTRGYKPPAIPNMNVFEATVSCVGDDGTIFVVPKLSEFELIKMTNEIQSNLKCLG-----LLEPYFWKKGEACAVR-GSDTLWYRGKVMEVVG--GAVRVQYLDHGFTEKIPQCHLYPILLYPDIPQFCIPCQLHNTTP----------VGNVWQPDAIEVLQQLLSKRQVDIHIMELPKNPWEKLSIHLYFDGMSLSYFMAYY-------------------------KYCTSEHTEEMLKEKPRSDHDKKYEEEQWEIRFEELLSAETDTPLLPPYLSSSLPSPGELYAVQVKHVVSPN---------------------------------EVYICLDSIETSNQSNQHSDTDDSGVSGESESESLDEALQRVNKK------------------------------------------------------------VEALPPLTDFRTEMPCLAEYD-DGLWYRAKIVAIKEFNP---LSILVQFVDYGSTAKLTLNRLCQIPSHLMRYPARAIKVLLAGFKPPLRDLGE---TRIPYCPKWSMEALWAMIDCLQGKQLYAVSMAPAPEQIVTLYDDEQHPVHMPLVEMGLADKDE", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F1R3C5-1", "uniprot_id": "F1R3C5_DANRE", "id": "F1R3C5-1", "name": "", "aln": "-------------------MS--ETAVTCKICGSPYTLPEDEAVGNLPHVLLCGHIFCCTCLRALQSQGNVITCPECQMDTRTSEEG----VDGLEVDSRI----------IGLIYTARMN---TKKGHSGDKWKSQKFKSPPSSAAVHTEENAEGKPDVVKVLDEALTKATENLNQLDKLHQTLANGVHGQLRKE--------RSRIIREIDEAVEKAKSILLKRRSMLVSTLS-SVDLLFSGGQMECKRIEERIKELR-------------TAIQKARHVRQVPSLETYCDLEKILETLHIPVDLESYDMSSLTLRSG----LSCHLQVDGFTESVKVFLKITDTDDNCIVEEITVEPFQHVVKSGVEMWDNSSQSVQGKADAIPRKSNNTRRFMEKMMEDTCPEIADTRVNAGLGRNLPVHEPRRMERYNKGYRKQRRPQFEKPTNP------------------------------QPKLVQYVVTTHIVNPGHFYVRYMAEHKLGQKLTKKISEFCSGERSFFTFS---DEITTGSLLFISWKDDMWCRVKVTELFQKECFQS-----VTKCLASEVSRLCVYFLDYGFFKGFSIP--------------SDGGLSGLNECLRRPDG-ITLIEMANWAPLAIKCSLKDIIPADLVKGWSSEASEEMRNVLRNETAEMQVFGEDGDALLVDLKKTSMADLKKNSMVSLREHLVFMELARFYCPVITTG---SAPLLFYPSVQPSLNVEVNAMVSHVNTPSDFYVQLVEN-TEYPLLHSKLQDCYNQPKSNNECQVYCPSLSQACVA-FHDQEWSRVQVTGFPGGRMVEVRFVDFGYKRTLSVKDLRHIKDEFFVLPEMALWCNLNDVISSQE---TWANEACESFKELVEGKLMTVVAKKNVPSSKPVPVCLFEIS--DDCTGASIGDELVKKGYAVYNKDTQVRDAQPLETTSWDPPFEEEALPVVMTPSSASEELKPSLSLPSCL-KDIRVRVTHVTSPGNICVQLLQFDNQLKRIHDTLKNLFSKSEP---QEMQWEAEMYCAVNNTG--VWERGQVCSVSTCGVAEVLRCDFG-----------NTVKLHVDNLRPLHP--DLIGSFLLECNLSGVRPAGGRSTWTATACDFISHYLTGAMALMAIK-----EPSTRPVLVSLFCSN-----RAGQNVSFADFLISEGLALKERKAEMVFSEESVLVTEPQPVISPTQT----------------------PPTPSRRINPPP---------------------ERVKTHSYPPPELPPCGHILMSISAVSEQGVIYAMTHQAVCEFDRLRERLQQHIKTLP-----RQKNYNWKGVLGCAVM-GTDMFWYRGQVQEVIG--GHVKVRYVDQGLVESIPVCHVYPMVLCEDVPQLCVPCQINGVLP----------IGKGWQWDAVVLMKELLLGRSVNVQIMEHPKDPCGCVTVEIMVDGMALSKIMVHH-------------------------QYATFDP--AISSQEDYVVKPPMPDLDDWDLNTEGLEE---QPPVLGVYKELHIPKERKHFPAKVKHIRTPN---------------------------------EVFLCVLDKSLCKLE---------------QDESMEETLEQVNEN------------------------------------------------------------IENLSLLTDFPIECLCLAEYS-DGKYYRAKILGFSEVTPS--VKLLVRHVDFGSDDIIPLHKLRQLPASLHHFPCAAVYVKLAGFKPTNVSSDL---ERIPYSLDWTMKAMMEMIDLLNG-ELTAVVTATKPQLTVLLYNADGTLVHTPLVEKGLADYE-", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VE55-1", "uniprot_id": "Q9VE55_DROME", "id": "Q9VE55-1", "name": "", "aln": "MIADDSGIKPFDPKFVASNLQNLLRCPKCSKCFTYLYNTNSEEDNHRPFLLGCGHTLCESCLWNDRLDPKCAVCHSPAPPTIVAKRSDCKSVANLRDLYELNYHVLGRTSSLSYLLPFAKDSANQSLSPSSISEIVQTVKCSECGNATASGECRQCNAFYCRRCFDAVHKRSRVLKSHIFRNSTEQDSSFSKKLRVGDQYFTLPSQNLCIHHRMPKDKYCMKCYRSHCQICSTVHHSGHRIRKLIEINQSYASEIPTTLNSLNMAHIHVLNGKQVVQRAKQKLNDYATETLASISKRFSHLHGLLQVAELQVIEKLRESSLPPQLKLNEAMGQLSGYETVIERLTKSLNSGVGNDMAVPRDVSLRWLLKLICEHLEKIPTTVQVSKVDENPYRVTCSRFMDISNIFKCEFVNPNIQVCFKTDLEISRSLSSSPKGEITFLTSSSSSK----ENFDPHSRKLLLAQNSKLKKATQVSQSQKKRGKNATEVAQSSLNSTAAIIDEFPAKDLDFLHNFSSLDITKRNKTTEDSSDWFKTDTLVRVRSVQSPEDFYVQGIHAAQRLREELDTFAHTLSDSSSVPPTIVVGQNYIIHHKDKDRYYRALVSQKLTNENLYNVFLTDIGVHLHVRCSDFRVVPERISHLPYSAVHCSLSELMPKNGESEWDSKASAFLKQIVQNNPVRVIVK----KALTYELHGVDLITSNYDTNISVRDSFLYCGLAISR-DGAPLWLPPAPTALRLPRISFRFGDVYMVQMLHVEDPQEFYVMRHDYEKKRLWLQFSLQEAMDRINISQLQNIFLGQLHLGCVL-QSGGQWKRASIEQILPDGYVLVHLVDEGPSQKVFWDQLFVLPQKFWDTG-LAIKCCLADVETRAEHSYTWTPEGTTLFKQLTSNPRLYMDVISCTEDLVYVSLHFERSN--SETTSVGVQLVAHGHCTSSGESSRMITPTVSNRSVRFDEETKKFIAQQKVRPVELSPYRMPDN---TERNKRTTVNILYVRKPDEFYVTLPHFQKAINNLQKSVQKAAAAMYQNMLPRTDWQVGDMCYARVQANCDSQALWYRGVVTGVIPPGITCPIVRYQVHLRDLGELIDDVHSSSLANIDEADMRISSSAKRCHLHGIRPIG--DEWSKDAIDFFMDQLKAYNEIHVTGRGRTENSLSVILWGSLSILTGPFSPATIKYVNINKALLMAGMAEKDHNSDSEDDQQSMPENVSVNSEEAAKANDWESCLSKIDGTSKTNDSLNLIESRSVTVGFEHNEDMPPLALLEDLGNTKNTTGETTPPAGWTTRRKCDKSVFTAIATNVTYECCIYLTLASDKPFIEHMGNLLVREYKPLMDKQKERSTSYTYKVGQAVVVTYHMDNMIYRGIVQRLENNHNEYTVYYVDYGNMELVKADEMLPYAPFPDLNAMCFLVELHGVRS---------KQGKYSLKEMDTVHLNLVMKLSGVRIVDDETVGPNKIPKCQIKVGNVDIATMMIDSGMSVPIEKQTIKNNTKYLPSQKFLEDFKVFDELDHLAAGEGELSDKEAPPTQRKHDSISSVQQPPTKKFLVDQEEVEAFECDQDFDCQQAAQKMHLNNNFYLGDFGKYADETTARDEDEPHSNSSKSIDMEVFANVNDSQLEPLNSFATEQLIRRIALRQQEIKDSITFSPIDTSSVRSFYDASASFKTLSLPNGVKEFYCTVDNVLSDTELQIAPCLSEFTKHEISLIQETSTLIKDAEPLMEPKVGDLCLARYSRDKQWYRANIKEISPILSPTSEQVTVFYIDFHDTEKVSFNHLKVMPSQLFMFPLRSFCVKLHGIKRNKSFKEKSVRQALQACLCQHPLVFARVHYPLNYYPNRPNCDADLIEVELYENRHEKKLVYQSLCENWMFLKKS", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . . . . . *** :* ** : . * . * . . : . : : . . : . :.. . . .. . :*: :. . : . : : : : . . . . . .* . * .:: *: : .* ..: : : *: : :: . .. :. : :. .: . : . : : . . . : . . : .. .. .. .. : . . . :. . . . : . : :: : : : : . : : . : .. : .: : . * ***.:::* : . *..:*. : :::.::.. : * * :*: . : :*:*: ::: ** .. * . : *:: * :**: : . * .::: . . .: :: .** . * *..: : * *: ** * . .: .:: : ::* *: * * : . . *: :. *:: ... : . . . : : : : ..: . : : . : . :* :: * .. : * * : * .* :: * :: :. :...: .*: * .. . : * : : . :: * :. :. .* * .:** * . *: * * : *.. . : : .: : *.. . *: *:* :::. . ...* . . .: : . . * : . . : : : : *: : :: : : . * * * :* .* * : *** * .: . . * *:* * * : .: * * :*. :: . . *: : : :*: . : : . . . .: ...: :: :* .: : : : . : . . : . :: : . :. : : *:: : . . :. . . ::. .: . :: * : ***.* * :***:* :. . . .: * .:*: :.:::* :* * :* :. * * *:* : . .: : *: . * : : : *: .* * : . ", "identical_positions": 123, "similar_positions": 407, "identity": "6.53%" }, { "cls_id": "homologset.agr.MGI:1353420", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9R000-1", "uniprot_id": "ITBP2_MOUSE", "id": "Q9R000-1", "name": "Integrin beta-1-binding protein 2", "aln": "MSLLCYNKGCGQHFDPNTNLPDSCRYHPGVPIFHDALKGWSCCRKRTVDFSEFLNIKGCTVGLHCAEKLPEVPPQPEGPATSS-LQEQKPLNTIPKSAETLFRERPKSEMPPKLLPLLISQALGVALEQKELDQEPGAGLDNSLIWTGSSCQNPGCDAVYQGPESDATPCTYHPGAPRFHEGMKSWSCCGIQTLDFGAFLAQPGCRVGRHDWAKQLPASCRHDWHQTDSVVVLTVYGQIPLPAFNWVKASQTELHVHIVFDGNRVFQAQMKLWGVINVEQSSVSLMPSRVEISLVKADPGSWAQLEHPDSLAEKARAGVLLEMDEEESEDSDDDLSWTEEEDEEEEEAMGE", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D3ZW59-1", "uniprot_id": "D3ZW59_RAT", "id": "D3ZW59-1", "name": "Integrin beta-1-binding protein 2", "aln": "MSLLCYNKGCGQHFDPNTNLPDSCRYHPGVPIFHDALKGWSCCRKRTVDFSEFLNIKGCTVGPHCAEKLPEVP-QPEGPATSS-LQEQKPLNTIPKSAETLLRERPKSEMPPKLLPLLISQALGVALEQKELDQEPGAGLDNSLIWTGSSCQNPGCDAVYQGPESDATPCTYHPGAPRFHEGMKSWSCCGIQTLDFGAFLAQPGCRVGRHDWAKQLPASCRHDWHQTDSLVVLTVYGQIPLPAFNWVKASQTELHVHIVFDGNRVFQAQMKLWGVINVEQSSVSLMPSRVEISLVKADPGSWAQLEHPDSLAEKARAGVLLEMDEEESEDSDDDLSWTEEEDEDEEEAMGE", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9UKP3-1", "uniprot_id": "ITBP2_HUMAN", "id": "Q9UKP3-1", "name": "Integrin beta-1-binding protein 2", "aln": "MSLLCRNKGCGQHFDPNTNLPDSCCHHPGVPIFHDALKGWSCCRKRTVDFSEFLNIKGCTMGPHCAEKLPEAP-QPEGPATSSSLQEQKPLNVIPKSAETLRRERPKSELPLKLLPLNISQALEMALEQKELDQEPGAGLD-SLIRTGSSCQNPGCDAVYQGPESDATPCTYHPGAPRFHEGMKSWSCCGIQTLDFGAFLAQPGCRVGRHDWGKQLPASCRHDWHQTDSLVVVTVYGQIPLPAFNWVKASQTELHVHIVFDGNRVFQAQMKLWGVINVEQSSVFLMPSRVEISLVKADPGSWAQLEHPDALAKKARAGVVLEMDEEESDDSDDDLSWTEE--EEEEEAMGE", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "***** ****************** :**********************************:* ********.* ********* ********.******** *******:* ***** ***** :**************** *** ******************************************************************.****************:**:************************************************** *************************:**:******:********:*********** *:*******", "identical_positions": 323, "similar_positions": 14, "identity": "92.02%" }, { "cls_id": "homologset.agr.MGI:1353421", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D4ADK7-1", "uniprot_id": "D4ADK7_RAT", "id": "D4ADK7-1", "name": "Melanotransferrin", "aln": "MRLLSVTFWLLLSLRTVLC----------VMEMQWCTISDPEQQKCKDMSKAFQG-----AGIQPSLLCVQGTSTDHCVQLIKDQK-ADAITLDGGAIYQAGKEYGLKPVVGEVYDQDIGTSYYAVAVVRR---NSNVTINTLKGVKSCHTGINRTVGWNVPVGYLVETGHLSVMGCD-VLKAVGDYFGGSCVPGAGETSH------SESLCRLCRGDSSGHNVCDKSPLERYYDYSGAFRCLAEGAGDVAFVKHSTVLENTDGKTLPSWGKALMSQDFQLLCRDGSRADITEWRRCHLAKVPAHAVVVRDDMDGG----------LIFRLLNEGQLLFSHEDSS------------------------------------------------------------FQMFSSKAYGQKNLLFKDST--LELVPIATQNYESWLGQEYLHAMKGLLCDPNRLPHYLRWCVLSVPEIQKCGDMAVAFSRQSLKPEIQCVSAESPEHCMQQIQAGHIDAVTLRGEDIYRAGKAYGLVPAAGELYAEEDRSNSYFVVAVVRRDSSYSFTLDELRSKRSCHPGLGSPAGWEVPIGSLIQRGFIRPKDCDVLTAVSEFFNASCVPVNNPKNYPS-----SLCALCVGDEKGRNKCVGSSQERYYGYSGAFRCLVENAGDVAFLKHTTVFENTNGHNPEPWASHLRWQDYELLCPNGARAEVDQFQACNLAQMPSHAVMVHP-----DTNIFTVYGLLDKAQDLFGDDHNKNGFQMFDSSKYHSQDLLFKDATVRAVPVR-EKTTYLDWLGPDYVVALEGMLSQQCSGAGAAVHRVPPPALLLLALAAGLLPRVL-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9R0R1-1", "uniprot_id": "TRFM_MOUSE", "id": "Q9R0R1-1", "name": "Melanotransferrin", "aln": "MRLLSVTFWLLLSLRTVVC----------VMEVQWCTISDAEQQKCKDMSEAFQG-----AGIRPSLLCVQGNSADHCVQLIKEQK-ADAITLDGGAIYEAGKEHGLKPVVGEVYDQDIGTSYYAVAVVRR---NSNVTINTLKGVKSCHTGINRTVGWNVPVGYLVESGHLSVMGCD-VLKAVGDYFGGSCVPGTGETSH------SESLCRLCRGDSSGHNVCDKSPLERYYDYSGAFRCLAEGAGDVAFVKHSTVLENTDGNTLPSWGKSLMSEDFQLLCRDGSRADITEWRRCHLAKVPAHAVVVRGDMDGG----------LIFQLLNEGQLLFSHEDSS------------------------------------------------------------FQMFSSKAYSQKNLLFKDST--LELVPIATQNYEAWLGQEYLQAMKGLLCDPNRLPHYLRWCVLSAPEIQKCGDMAVAFSRQNLKPEIQCVSAESPEHCMEQIQAGHTDAVTLRGEDIYRAGKVYGLVPAAGELYAEEDRSNSYFVVAVARRDSSYSFTLDELRGKRSCHPYLGSPAGWEVPIGSLIQRGFIRPKDCDVLTAVSQFFNASCVPVNNPKNYPS-----ALCALCVGDEKGRNKCVGSSQERYYGYSGAFRCLVEHAGDVAFVKHTTVFENTNGHNPEPWASHLRWQDYELLCPNGARAEVDQFQACNLAQMPSHAVMVRP-----DTNIFTVYGLLDKAQDLFGDDHNKNGFQMFDSSKYHSQDLLFKDATVRAVPVR-EKTTYLDWLGPDYVVALEGMLSQQCSGAGAAVQRVPLLALLLLTLAAGLLPRVL-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P08582-1", "uniprot_id": "TRFM_HUMAN", "id": "P08582-1", "name": "Melanotransferrin", "aln": "MRGPSGALWLLLALRTVLG----------GMEVRWCATSDPEQHKCGNMSEAFRE-----AGIQPSLLCVRGTSADHCVQLIAAQE-ADAITLDGGAIYEAGKEHGLKPVVGEVYDQEVGTSYYAVAVVRR---SSHVTIDTLKGVKSCHTGINRTVGWNVPVGYLVESGRLSVMGCD-VLKAVSDYFGGSCVPGAGETSY------SESLCRLCRGDSSGEGVCDKSPLERYYDYSGAFRCLAEGAGDVAFVKHSTVLENTDGKTLPSWGQALLSQDFELLCRDGSRADVTEWRQCHLARVPAHAVVVRADTDGG----------LIFRLLNEGQRLFSHEGSS------------------------------------------------------------FQMFSSEAYGQKDLLFKDST--SELVPIATQTYEAWLGHEYLHAMKGLLCDPNRLPPYLRWCVLSTPEIQKCGDMAVAFRRQRLKPEIQCVSAKSPQHCMERIQAEQVDAVTLSGEDIYTAGKTYGLVPAAGEHYAPEDSSNSYYVVAVVRRDSSHAFTLDELRGKRSCHAGFGSPAGWDVPVGALIQRGFIRPKDCDVLTAVSEFFNASCVPVNNPKNYPS-----SLCALCVGDEQGRNKCVGNSQERYYGYRGAFRCLVENAGDVAFVRHTTVFDNTNGHNSEPWAAELRSEDYELLCPNGARAEVSQFAACNLAQIPPHAVMVRP-----DTNIFTVYGLLDKAQDLFGDDHNKNGFKMFDSSNYHGQDLLFKDATVRAVPVG-EKTTYRGWLGLDYVAALEGMSSQQCSGAAAPAPGAPLLPLLLPALAARLLPPAL-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M3B3G9-1", "uniprot_id": "A0A8M3B3G9_DANRE", "id": "A0A8M3B3G9-1", "name": "Serotransferrin", "aln": "MDTWTFLSVLLALTHYVSG----------QSTIRWCVISVAEESKCKAMAQAFSS-----ASVRPALKCVLAASKAECAQKLTQKKEVDAFSASAKDIYDIGKLASFKISAGESGSDGKGITYYGVAVVKKT--NAAININNLKGKKSCHTGKNRTAGWNVPLGYLIDSGMMSVMGCN-IPQGVADFFNASCIPGAKDD--------PASLCQQCVGDRTGQFKCDPSNKELYYAYDGAFRCLVEDAGDVAFVKHTTVSENTDGK-GASWAQELQSKDYQLLCRDGTRSPVTDYEKCHLARVPSRGIVIHPDITTS----------VVYNMLTEG-----LQKSG------------------------------------------------------------FSMFSSADFGGENLLFSDTS--TKFIQAGNENYKEWMG-RYYHILKAMDCSQSDIPSQLQWCVLSHGEQQKCADMAVAFKNKNLIPNIQCVYGASVEDCMKKIQNKEADAITLDGGYIYTAGKSYGLIPAVGESYTGDSDGSIYYAVAVLRKSNRDIQRFSDLKGKRSCHTGYGRTAGWNIPMGLLIEKGIIRPQTCQVAQAAGEFFESACVPGADQKDFPE-----NLCKQCIGDSSGQFKCVK-GKDLYDGYDGAFRCLVENHGDVAFVKHSTVFQNTDGNNTDPWAVNLDSREFQLLCSQESRAEVTQFTKCNLARVPSHAVMIRP-----DTNHHIIFGLLDKAQRFFGVNS-ASGFKMFDSKAYEGSDLIFKDSTITLIGVG-ERKTYEEWLGQSY---LDSLIAMECS---ASSTVFSFSSLLLMSIVSSLVSLLAL", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VTZ5-1", "uniprot_id": "TRFM_DROME", "id": "Q9VTZ5-1", "name": "Transferrin 2", "aln": "MASSLVFVALVGALCFTLANAQHHYDEHKTTRMVWCTKSQAEQYKCQNLTVAIERDRALFDEVFLNLTCFMAYSADECIHHIDREK-AHITTLDAGDVFTAGRYNSLIPIMQEKLEGG-FADYQSVAVIKKGSLPDLNNLRDMRNKRVCFPWVGSLAGWIVPIHTLQREGGMEVVDCNNQVKTAASYFNNSCAVYSLSDKHNPIGDNSDKLCTLCTGKIPGG---RCSSADPYFGYEGAFKCLLE-KGDVAFLRHSTVNEMLQTTEFKNIAPDT----FELLCRDGRRASINDYRQCNWGQVPADAIVTSSARSFSDRKQYQQFLKRIAELYSDGTRDDQSRQGGQSFNSRNNINDQNAYGQFDNNDPYRTQNQYDQYRSERLDSSFAEERNQQDGTNTSILYEKFRIFESKRYGKPNLLFQDSSRALTVIPEDDQSFTKYLGPAINFIYGIRECP----VPAMTLCVTSENELDKCIKMRTALKAHLLKPELICKKMHSHINCMQFIEAGKADISVFDAGDVYTGGLNYDLVPFMSEVYNLGEPE--YYVVAVAKEDDP-DTELTYLKGKNTCHTGINTAAGWTYPMALFISNGWIRPYGCDSVRAAAEYFTKSCVPGAISNEYNTGVPYDSMCDLCHG--TSYRYCRRDASEEYYGHTGAFRCLVEGGGHVAFMKHTTVMESTGGKRKEWWARNALNDDFELLCTDGTRAEIQDYKRCNLGKVKANAVVTRGGVNYNETQMNAYINLLTYAQQLYGRKEVDAFSFSMFSSPIGHYDLIFQDATRQLQVIPPNKRRYDAYLGSDFMR----ARRITDCYAGASQLALSVGLLLVGSLVAML------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* *: . : **. * .*: ** :: *: : * *. . * .* : : :: .. : .. :: *: .: * . * .***::: .: ::. : *.. . .** **: * * :.*:.*: : ...:*. ** : . . .** * *. .* * : *: *.***:** * *****::*:** * : . . . ::****** *: :.::.:*: .:**: .:* . : .: .:* . .. * :*.* :. :***.*:: .: :.: ::* * : ** * * :** .* .*: : * *:: * * .**: *: . * .: . :* .* *.*:* .* * . *:.*** :... : *:.*.:**. . .*** *:. :*..* *** *: *..::* :*** ::: :* * * . * ..: * *: ******** *.***::*:**::.*.*:. : ** . :::***.: :***: :: ***.:: .:**: : :*: .** ** ::* . : *. **:*:*:* : :: * :** .: . *. . **: ::.: * ", "identical_positions": 176, "similar_positions": 218, "identity": "20.75%" }, { "cls_id": "homologset.agr.MGI:1353422", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "B2RYE0-1", "uniprot_id": "B2RYE0_RAT", "id": "B2RYE0-1", "name": "SAM pointed domain-containing Ets transcription factor", "aln": "-----------------------------------------------------------------------------MGSASPGLSNVSPG-CLLLSPDVALRTGVEKAASG-------AMGLEKQEWSPSPPATPEQGLSAFYLS---YFN-MYPEDGSWVAKVPEASAREDHPEEPE-------------------QCP--VIDSQASGN---------TLDEHS--------------------LEQVQSMVVGEVLKDIETACKLLNITADPGDWSPGNVQKWLLWTEHQYRLPPAGKAFQELGGK--ELCAMSEEQFRQRAPLGGDVLHAHLDIWKS------AAWMKERTSPGALHYCAATHPARPGFLPASTSEEG--------------WTDGEVDSSCS------------------GQPIHLWQFLKELLLKPHSYGRFIRWLNKEKGIFKIEDSAQVARLWGVRKNRPAMNYDKLSRSIRQYYKKGIIRKPDISQRLVYQFVHPV--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9WTP3-1", "uniprot_id": "SPDEF_MOUSE", "id": "Q9WTP3-1", "name": "SAM pointed domain-containing Ets transcription factor", "aln": "-----------------------------------------------------------------------------MGSASPGLSNVSPG-CLLLFPDVAPRTGTEKAASG-------AMGPEKQEWSPSPPATPEQGLSAFYLS---YFN-MYPDDSSWVAKVPEARAGEDHPEEPE-------------------QCP--VIDSQASGS---------TLDEHS--------------------LEQVQSMVVGEVLKDIETACKLLNITADPGDWSPGNVQKWLLWTEHQYRLPPAGKAFQELGGK--ELCAMSEEQFRQRAPLGGDVLHAHLDIWKS------AAWMKERTSPGTLHYCAS------------TSEEG--------------WTDGEVDSSCS------------------GQPIHLWQFLKELLLKPHSYGRFIRWLNKEKGIFKIEDSAQVARLWGVRKNRPAMNYDKLSRSIRQYYKKGIIRKPDISQRLVYQFVHPV--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O95238-1", "uniprot_id": "SPDEF_HUMAN", "id": "O95238-1", "name": "SAM pointed domain-containing Ets transcription factor", "aln": "-----------------------------------------------------------------------------MGSASPGLSSVSPS-HLLLPPDTVSRTGLEKAAAG-------AVGLERRDWSPSPPATPEQGLSAFYLS---YFDMLYPEDSSWAAKAPGASSREEPPEEPE-------------------QCP--VIDSQAPAGSLDLVPGGLTLEEHS--------------------LEQVQSMVVGEVLKDIETACKLLNITADPMDWSPSNVQKWLLWTEHQYRLPPMGKAFQELAGK--ELCAMSEEQFRQRSPLGGDVLHAHLDIWKS------AAWMKERTSPGAIHYCAS------------TSEES--------------WTDSEVDSSCS------------------GQPIHLWQFLKELLLKPHSYGRFIRWLNKEKGIFKIEDSAQVARLWGIRKNRPAMNYDKLSRSIRQYYKKGIIRKPDISQRLVYQFVHPI--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P29775-1", "uniprot_id": "ETS4_DROME", "id": "P29775-1", "name": "DNA-binding protein D-ETS-4", "aln": "MEYEKMLYMPAASEMPHSPQLKPHQFQAHTPTDQYSSYADNFDLSLLPQESASIPTTVFQYNAPQIKVECAWDSQPIQQQQQPTAPYTNPSSHQLIPPPAYPHSAYPSPQSSPLQSEFAAYGLGRFGGSYDSLNSPSPSLEAVSIKQELHILPPSPPESNCETPSPRSSCGESIKAEPLDADIESLIDLNSLLQQQSLQSPQNLQDTKPDHQLLRECLEDTSFQKRHNLKPLALESFIGGLAEVRGDFEPVISLALEHAKREADAICAELQISQDPNGWSPAQVHAWLRSTLAQFRLPPVADLELHFCENGAALALLSEEEFVRRLPESGSTLHAQLEIWKMAYADQPAHQQHSQQSASTDHWPASYAMPHLDLDYNEDSEDDDDMEADAQVAPLNGSTTSPPATNASNGGTATVKRPNGGRTGGGGSHIHLWQFLKELLASPQVNGTAIRWIDRSKGIFKIEDSVRVAKLWGRRKNRPAMNYDKLSRSIRQYYKKGIMKKTERSQRLVYQFCHPYSQ", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . .* . ..*. *: * . ::. .. :. * * : * .. :*. .*.*. :. :: * :.. : * : . *. ** *.* : *::. ::::: :* * *:.: .. :: :: * *:*: ** .***.:*: ** * *:**** .. .: : *. :***:* :* * .*..***:*:*** * :.: *..: *: *: **:. * . :..* *. *********** .*: * ***:::.*********.:**:*** ************************::*.: ******** ** ", "identical_positions": 127, "similar_positions": 103, "identity": "24.52%" }, { "cls_id": "homologset.agr.MGI:1353423", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZXZ1-1", "uniprot_id": "D3ZXZ1_RAT", "id": "D3ZXZ1-1", "name": "Zinc finger protein 292", "aln": "MADDEAEQERLSGG--SCAAELRRLGERLQELERRLCESREPAVEAAAAYCRQLCQTLLEYAEKWKTSEDPLPLLEVYTVAIQSYVKARPYLTSECESVALVLERLALSCVELLLCLPVELSDKQWEQFQTLVQVAHETLMESGSCELHFLATLAQETGVWKNAVLSTILSQEPLDKEKVNEFLAFEGPILLDMRIKHLIKTNQLSQATALAKLCSDHPEIGTKGSFKQTYLVCLCTSSPSEKLIEEISEVDCKDALEMICNLESEGDEKSALVLCTAFLSRQLQQGDMYCAWELTLFWSKLQQRVEPSVQVYLERCRQLSLLTKTVYHIFFLIKVINSETEGAGLATCIELCVKALRLESTENTEVKISICKTISCLLPEDLEVKRACQLSEFLIEPTVDAYYAVEMLYNQPDQKYDEENLPIPNSLRCELLLVLKTQWPFDPEFWDWKTLKRQCLALMGEEASIVSSIDELNDSEVYEK-VDYQGERGDTSVNGLSAG-LGTDSSLLIDTGDEKQKKKEIKELKDRGFISARFRNWQAYMQYCLLCDKEFLGHRIVRHAQKHYKDGVYSCPICAKNFNSKESFVPHVTLHVKQSSKERLAAMKPLRRLGRPPKITATHEN--QKTNTNTVAKQEQRPIKKNSLYSTDFIVFND--NDGSDDENDDKDKSYEPEVIPVQKPVPVNEFNCPVTFCKKGFKYFKNLIAHVKGHKDSEDAKRFLEMQSKKVICQYCRRHFVSVTHLNDHLQMHCGSKPYICIQMKCKAGFNSYAELLAHRKEHQVFRAKCLFPKCGRIFSQAYLLYDHEAQHYNTYTCKFTGCGKVYRSQSEMEKHLDDHSAP-EKVLPPEDQLTPSGN-----EVTQNSEGTTGEGR----SEHSIEKSEGPDRSGDWEKNKAESAVTTHSQISASELRQADIPLSDGLGNPGDTTVLQTN-EVAVSIKVSVNHGIEDDFGKQENLTMEGTGEPLITDVHKPGEGAGVHFRHPGFQEKKDHECLNKAQTAQNSLANSESLKMGDLNPQSLERQVNTLTTFSVQNEGGLEDSSQICKFECGGDVKTSSSLYDLPLKTLESVAFVPSQPDLSSPLGAPSVPPKAPGQKFSCQVEGCTRTYNSSQSIGKHMKTAHPDQYAAFKLQRKTKKGQKSNNLSTPDHGKCVYFLPSQVSSSNHAFFTPQTKASGNPACSAQLQHVSPSIFPAHLASVSTSLLPSVESVLSPNMPSQDKHVQDGMLCSQMENLSNAALPAQMEDLTKTVLPLNIDSGSDPFLPLPTENS--SLFSSPAHSENNSVFSQLESSTNHYPSPTEGNLNSSFLKGGSSENGAFPSHVSTADDLSSTSAQQSAPKKVKKDRGRGPNGKERKPKHNKRAKWPAIIRDGKFICSRCYRAFTNPRSLGGHLSKRSYCKPLDGAEIAQELLQTNRQPSLLASMILSTSTVNMQQPQQSNCNPETCFKDPSFLQLLSVENRPNFLPSTFPRCDVSNFNAGVSQEGSEIIKQALETAGIPSTFESAEMLSQVVPIGSVSDAAQVNAEGMPGPTVTPLLQTVCHTNTSPSSQNQTPNSKTSNLKECNSLPIFTTNDLLLKTIENGLCSNSFSSSTEPPQNFTNNSTHVSVISGPQNTRSNHLNKKGNSASKKRKKVTPAVIVSNTSQNVVPTDLT-MGLASKNLTVPDTNTR-DMIPDCEPQALVENLTQKLNNIDNHLFLTDVKESCKASLEPHTMLTPLTLKTENGDSRMMPLNSCTP-VSSDLQISEDNVIQNFEKTLEIIKTAMNSQILEVKSGSQGTGETTQNAQINYSMQLPSVNSIPDNKLPDSSQCSSFLTVMPTKHNIPQSEALHKEDQIQDILEGLQNLKLETDISAPPSQATLINKSVALSPTPTKSTPNI-IVQPVSEVIHVQLNDRVNKPFVCQNQGCNYSAMTKDALFKHYGKIHQYTPEMILEIKKNQLKFAPFKCVVPTCTKTFTRNSNLRAHCQLVHHFTIEEMVKLKIKRPYGRKSQGENLSSPQINQVKKQLPMAEEAKTESQPAFEVPAVAGEDALDNVAVIPENQLAEKKSPEKPESSSQPVTASTEQYNAN-----------------------------------------------------------LGNLKTKGRKNKRHRKEKEEKREKNPVSQSFEFPTRYSSYRPYCCVHQGCFAAFTIQQNLILHYQAVHKSNLPTFSAEVEEESE----------AVKESEETEPKQSMKEFRCQVSDCSRIFQAITGLIQHYMKLHEMTPEEIESMTAAVDVGKFPCDQLECKSSFTTYLSYVVHLEVDHGIGTRTSKTE---EDGIYKCDCEGCDRIYATRSNLLRHIFNKHNDKHKAHLIRPRKLT-GQENISSKANQEKSKSKHRAIKHNRFGKDGMKGPKTKRKKKSNLESKSAKIVQIEEDKPYSLKRGKHVYSIKARNDALSECTSKFVTQYPCMIKGCTSVVTSESNIIRHYKCHKLSKAFTSQHRNILIVFKRYGNPQEKEVSEQEDEKNDKKDPDSSVLEKNDNS-QPASIPQEEGMKGEKDEMDELTELFITKLINEDSTNTETQVSTTLKVNNDFQEHDSCISERQKTGNLKRVYKEKNITQNKKRKIDKTEPEVPLVVNKTHKEEETAVAVQTTEEHPASFDWSSFKPMGFEASFLKFLEESAVKQKKNTDRDHSHSGSKRGSHSNSRKNVDKTAVTGGNHVCSCKESEIFVQFANPSKLQCSENVKIVLDKTLKDCSELVLKQLQEMKPTVSLKKLEVLSNDPDRTVLKELSLGKATGRGQY", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9Z2U2-1", "uniprot_id": "ZN292_MOUSE", "id": "Q9Z2U2-1", "name": "Zinc finger protein 292", "aln": "MADDEAEQERLSGG--GCAAELRRLGERLQELERRLCESREPAVEAAAAYCRQLCQTLLEYAEKWKTSEDPLPLLEVYTVAIQSYVKARPYLTSECESVALVLERLALSCVELLLCLPVELSDKQWEQFQTLVQVAHETLMESGSCELQFLATLAQETGVWKNAVLSTILSQEPLDKEKVNEFLAFEGPILLDMRIKHLIKTNQLSQATALAKLCSDHPEIGTKGSFKQTYLVCLCTSSPSEKLIEEISEVDCKDALEMICNLESEGDEKSALVLCTAFLSRQLQQGDMYCAWELTLFWSKLQQRVEPSVQVYLERCRQLSLLTKTVYHIFFLIKVINSETEGAGLATCIELCVKALRLESTENTEVKISICKTISCLLPEDLEVKRACQLSEFLIEPTVDAYYAVEMLYNQPDQKYDEENLPIPNSLRCELLLVLKTQWPFDPEFWDWKTLKRQCLALMGEEASIVSSIDELNDSEVYEK-VDYQGERGDTSVNGLSAAGLGTDSGLLMDTGDEKQKKKEIKELKDRGFISARFRNWQAYMQYCLLCDKEFLGHRIVRHAQKHYKDGIYSCPICAKNFNSKDSFVPHVTLHVKQSSKERLAAMKPLRRLGRPPKITATHEN--QKTNINTVAKQEQRPIKKNSLYSTDFIVFND--NDGSDDENDDKDKSYEPEVIPVQKPVPVNEFNCPVTFCKKGFKYFKNLIAHVKGHKDSEDAKRFLEMQSKKVICQYCRRHFVSVTHLNDHLQMHCGSKPYICIQMKCKAGFNSYAELLAHRKEHQVFRAKCLFPKCGRIFSQAYLLYDHEAQHYNTYTCKFTGCGKVYRSQSEMEKHQDGHSHP-ETGLPPEDQLQPSGN-----DVNPDSGATAAGGR----SENSIDKNLGSNRSADWEKNRAEPAVTKHGQISAAELRQANIPLSNGLETRDNTTVLRTN-EVAVSIKVSVNHGVEGDFGKQENLTMEGTGEPLITDVHKPGIGAGVQLCHPGFQEKKGHECLN---EAQNSLSNSESLKMDDLNPQSLERQVNTLMTFSVQNEAGLEDNSQICKFECGGDVKTSSSLYDLPLKTLESITFVQSQPDLSSPLGSPSVPPKAPGQKFSCQVEGCTRTYNSSQSIGKHMKTAHPDQYAAFKLQRKTKKGQKSNNLNTPNHGKCVYFLPSQVSSSNHAFFTPQTKANGNPACSAQVQHVSPSIFPAHLASVSAPLLPSVESVLSPNIPSQDKHGQDGILCSQMENLSNAPLPAQMEDLTKTVLPLNIDSGSDPFLPLPTENS--SLFSSPADSENNSVFSQLENSTNHYPSQTDGNINSSFLKGGSSENGVFPSQVSSADDFSSTSAQPSTPKKVKKDRGRGPNGKERKPKHNKRAKWPAIIRDGKFICSRCYRAFTNPRSLGGHLSKRSYCKPLDGAEIAQELLQTNRQPSLLASMILSTSAVNMQQPQQSNFNPETCFKDPSFLQLLNVENRPTFLPSTFPRCDVSNFNASVSQEGSEIIKQALETAGIPSTFESAEMLSQVVPIGSVSDAAQVSAAGMPGPPVTPLLQTVCHPNTSPSNQNQTPNSKT--LKECNSLPLFTTNDLLLKTIENGLCSNSFSSSTEPPQNFTNNSAHVSVISGPQNTRSSHLNKKGNSASKKRKKVAPAVSVSNTSQNVLPTDLP-VGLPAKNLPVPDTNTRSDMTPDCEPRALVENLTQKLNNIDNHLFITDVKENCKASLEPHTMLTPLTLKTENGDSRMMPLSSCTP-VNSDLQISEDNVIQNFEKTLEIIKTAMNSQILEVKSGSQGTGETTQNAQINYSMQLPSVNSIPDNKLPDASQCSSFLTVMPTKS-----EALHKEDQIQDILEGLQNLKLENDTSAPASQSMLMNKSVALSPTPTKSTPNI-VVQPVPEVIHVQLNDRVNKPFVCQNQGCNYSAMTKDALFKHYGKIHQYTPEMILEIKKNQLKFAPFKCVVPSCTKTFTRNSNLRAHCQLVHHFTIEEMVKLKIKRPYGRKSQSENLSSPQNNQVKKQPSMAEETKTESQPAFKVPAATGDAALANATVIPEKQLAEKKSPEKPESSSQPVTSSAEQYNAN-----------------------------------------------------------LANLKTKGRKNKRHRKEKEEKREKNPVSQAFELPTKYSSYRPYCCVHQGCFAAFTIQQNLILHYQAVHKSNLPTFSAEVEEESE----------AVKESEETEPKQSMKEFRCQVSDCSRIFQAITGLIQHYMKLHEMTPEEIESMTAAVDVGKFPCDQLECKLSFTTYLSYVVHLEVDHGIGTRTSKAE---EDGIYKCDCEGCDRIYATRSNLLRHIFNKHNDKHKAHLIRPRKLT-GQENISSKANQEKSKSKHRTTKPNRSGKDGMKMPKTKRKKKSNLENKSAKVVQIEENKPYSLKRGKHVYSIKARNDALAECTSKFVTQYPCMIKGCTSVVTSESNIIRHYKCHKLSRAFTSQHRNILIVFKRYGNPQGKEISEQEDEKNDKKDPDSSVLEKNDNS-EPAAAPQEEGRKGEKDEMDELTELFITKLINEDSTNAENQGNTTLKGNNEFQEHDSCTSERQKPGNLKRVYKEKNTVQSKKRKIDKTEPEVSLVVNNTRKEEEPAVAVQTTEEHPASFDWSSFKPMGFEASFLKFLEESAVKQKKNSDRDHSNSGSKRGSHSSSRRHVDKAAVAGSSHVCSCKDSEIFVQFANPSKLQCSENVKIVLDKTLKDRSELVLKQLQEMKPTVSLKKLEVLSNNPDRTVLKEISIGKATGRGQY", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O60281-1", "uniprot_id": "ZN292_HUMAN", "id": "O60281-1", "name": "Zinc finger protein 292", "aln": "MADEEAEQERLSCGEGGCVAELQRLGERLQELELQLRESRVPAVEAATDYCQQLCQTLLEYAEKWKTSEDPLPLLEVYTVAIQSYVKARPYLTSECENVALVLERLALSCVELLLCLPVELSDKQWEQFQTLVQVAHEKLMENGSCELHFLATLAQETGVWKNPVLCTILSQEPLDKDKVNEFLAFEGPILLDMRIKHLIKTNQLSQATALAKLCSDHPEIGIKGSFKQTYLVCLCTSSPNGKLIEEISEVDCKDALEMICNLESEGDEKSALVLCTAFLSRQLQQGDMYCAWELTLFWSKLQQRVEPSIQVYLERCRQLSLLTKTVYHIFFLIKVINSETEGAGLATCIELCVKALRLESTENTEVKISICKTISCLLPDDLEVKRACQLSEFLIEPTVDAYYAVEMLYNQPDQKYDEENLPIPNSLRCELLLVLKTQWPFDPEFWDWKTLKRQCLALMGEEASIVSSIDELNDSEVYEKVVDYQEESKETSMNGLSGG-VGANSGLLKDIGDEKQKKREIKQLRERGFISARFRNWQAYMQYCVLCDKEFLGHRIVRHAQKHYKDGIYSCPICAKNFNSKETFVPHVTLHVKQSSKERLAAMKPLRRLGRPPKITTTNEN--QKT--NTVAKQEQRPIKKNSLYSTDFIVFND--NDGSDDENDDKDKSYEPEVIPVQKPVPVNEFNCPVTFCKKGFKYFKNLIAHVKGHKDNEDAKRFLEMQSKKVICQYCRRHFVSVTHLNDHLQMHCGSKPYICIQMKCKAGFNSYAELLTHRKEHQVFRAKCMFPKCGRIFSEAYLLYDHEAQHYNTYTCKFTGCGKVYRSQGELEKHLDDHSTPPEKVLPPEAQLNSSGDSIQPSEVNQNTAENIEKERSMLPSENNIENSLLADRSDAWDKSKAESAVTKQDQISASELRQANGPLSNGLENPATTPLLQSS-EVAVSIKVSLNQGIEDNFGKQENSTVEGSGEALVTDLHTPVEDTCNDLCHPGFQERKEQDCFNDAHVTQNSLVNSETLKIGDLTPQNLERQVNNLMTFSVQNQAAFQNNLPTSKFECGDNVKTSSNLYNLPLKTLESIAFVPPQSDLSNSLGTPSVPPKAPVQKFSCQVEGCTRTYNSSQSIGKHMKTAHPDQYAAFKMQRKSKKGQKANNLNTPNNGKFVYFLPSPVNSSN-PFFTSQTKANGNPACSAQLQHVSPPIFPAHLASVSTPLLSSMESVINPNITSQDKNEQGGMLCSQMENLPSTALPAQMEDLTKTVLPLNIDSGSDPFLPLPAESSSMSLFPSPADSGTNSVFSQLENNTNHYSSQIEGNTNSSFLKGGNGENAVFPSQVNVANNFSSTNAQQSAPEKVKKDRGRGPNGKERKPKHNKRAKWPAIIRDGKFICSRCYRAFTNPRSLGGHLSKRSYCKPLDGAEIAQELLQSNGQPSLLASMILSTNAVNLQQPQQSTFNPEACFKDPSFLQLLAENRSPAFLPNTFPRSGVTNFNTSVSQEGSEIIKQALETAGIPSTFEGAEMLSHVS-TGCVSDASQVNATVMPNPTVPPLLHTVCHPNTLLTNQNRTSNSKTSSIEECSSLPVFPTNDLLLKTVENGLCSSSFPNSGGPSQNFTSNSSRVSVISGPQNTRSSHLNKKGNSASKRRKKVAPPLIAPNASQNLVTSDLTTMGLIAKSVEIPTTNLHSNVIPTCEPQSLVENLTQKLNNVNNQLFMTDVKENFKTSLESHTVLAPLTLKTENGDSQMMALNSCTTSINSDLQISEDNVIQNFEKTLEIIKTAMNSQILEVKSGSQGAGETSQNAQINYNIQLPSVNTVQNNKLPDSSPFSSFISVMPTKSNIPQSEVSHKEDQIQEILEGLQKLKLENDLSTPASQCVLINTSVTLTPTPVKSTADITVIQPVSEMINIQFNDKVNKPFVCQNQGCNYSAMTKDALFKHYGKIHQYTPEMILEIKKNQLKFAPFKCVVPTCTKTFTRNSNLRAHCQLVHHFTTEEMVKLKIKRPYGRKSQSENVPASRSTQVKKQLAMTEENKKESQPALELRAET-QNTHSNVAVIPEKQLVEKKSPDKTESSLQVITVTSEQCNTNA----------------------------------------------------------LTNTQTKGRKIRRHKKEKEEKKRKKPVSQSLEFPTRYSPYRPYRCVHQGCFAAFTIQQNLILHYQAVHKSDLPAFSAEVEEESE----------AGKESEETETKQTLKEFRCQVSDCSRIFQAITGLIQHYMKLHEMTPEEIESMTASVDVGKFPCDQLECKSSFTTYLNYVVHLEADHGIGLRASKTE---EDGVYKCDCEGCDRIYATRSNLLRHIFNKHNDKHKAHLIRPRRLTPGQENMSSKANQEKSKSKHRGTKHSRCGKEGIKMPKTKRKKKNNLENKNAKIVQIEENKPYSLKRGKHVYSIKARNDALSECTSRFVTQYPCMIKGCTSVVTSESNIIRHYKCHKLSKAFTSQHRNLLIVFKRCCNSQVKETSEQEGAKNDVKDSDTCVSESNDNSRTTATVSQKEVEKNEKDEMDELTELFITKLINEDSTSVETQANTSSNVSNDFQEDNLCQSERQKASNLKRVNKEKNVSQNKKRKVEKAEPASAAELSSVRKEEETAVAIQTIEEHPASFDWSSFKPMGFEVSFLKFLEESAVKQKKNTDKDHPNTGNKKGSHSNSRKNIDKTAVTSGNHVCPCKESETFVQFANPSQLQCSDNVKIVLDKNLKDCTELVLKQLQEMKPTVSLKKLEVHSNDPDMSVMKDISIGKATGRGQY", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q5SNV1-1", "uniprot_id": "Q5SNV1_DANRE", "id": "Q5SNV1-1", "name": "", "aln": "MADEEAEQERSARS--DTSSALQALATRLQEIRGALEDRAEPAEESASQYCYQFCQTLLEYASLWRIEDEPLPVLEVYITALLSFAQACPLLSAQCEEVPLLLERLSLSCAELLLSLPWNIPDALWDRFRTSVQIAHPLVQEKGISHLTILSTIAREQGVWSNPTLQAILSSETPAGEEVHEFLTAEGPTLLRMRLKQLMKEGRADQAAALAKACADLSEFEEKGHFKQMHLVCLCTVAPQDVVMEELSKVDCRDALEMICNLEADGEEKAAFTLCSAFLTRQILQEDSYCAWELTLFWGNLLKRLEPSEQGFLDRCRQMSFLSKTVFHLLFFIKFIQTEMGKVGLPTCVEICIRALRLDSCEG-STKATVCKTISCLLPSDLEVKRACQLTEFLLEPTVDSYYAVETLYNEPDQKLDVEDLLVSNSLRCELLLVLKTQWPFDPEYWNWKALKRHCLGLMGEEASIVSSIDELNDGDLEGL------GEFNEDFKDMSQCFLDTTNELNDMADQKQKNR-EMKKLREKGFVSARFRNWQAYMQYCVLCDKEFLGHRIVRHAVTHFKDGSYFCPICLETFETKETLEPHVASHVKLSCKERLAAMKTSKQLASPKTATPDIPSLKAKSSENQVRKP-----------------------KTKSSSGGQANKLSSKGSNDSEGFG-GEGNTCPVQYCRKGFKYFRNLIAHVKDHGDNEEAKRFLEMQSTKIVCQYCRRQFVSVDHLNDHLQMHCGIKPYICIQLNCKASFNSNTELIVHKKEHTVFKARCMFPGCGKIFHEAYKLYDHEAQHYKTFTCKAPDCGKVFHSQSELDLHAESHITKVESKNTESQSIEPAEPHPEQCNQTEQDSAQPDPLSVMDLNDRGAESEEDRQSGMVIVKHSVENMLNSEFAVSADCVQPGTSKPDQLPTHQHIPQINDHPGKSTEGTRASRLKPHRPEESLLEALMSNSDPMPSTSSYQSVLEDLLPAPATNGQLQSADS-------ASTTPLYNNGVFRQYNPNPLTPSQASYQSLHSSRRTPPPQAAHNATPLVSLGQMLPPVSQTLPLQMASVPNDGQVLE----NKCVKPIDTTIVQVKERHKCPHETCTRDYSSYRSVTKHMKAVHPDFYTQWKLAKKNNVAGRS-----------------------------KHRSVNGGHSSVVTPR-------------------DQPAQRRPGVQTQKSLSQPTCYPSNCANPKYPSVSSHIAASPGHIRSNEMDNILDPIVLSQLGNGNNQPQMATDHLWDPRNNSVLQQQRCHSMTQSMNTLSSSHFTHMNPASNDDAQQR-GTSYTTLQSKRNGYPVPARADINQKLSNTSNDDLHAVGELNPTQVMGPNAVVTAQSSAETN----LGSAPMSVLSSYTDTMNSSVPKESSAAYLPQAEDSFPPVPSAQCLVKLERETTVGFPLSNNAPPSNGSSPSSQDNTGNASSDGEHKKVKRNRRTKWPAIVKDGKFICCR-CYREFNSPKSLGGHLSKRAYCKPFEEADLTADLPSSFLDLLNSPHPTPSSHVTLPQIKGPLDPKLYPNVTFPQANGTYTSIDKQMGGTLQSQSSPCVGSAQEQQMVPNPCGSYAQSSRLSETSVIQHTGSVKHQLQPSYSEMSSTLFNDSVSDP-----LLTQLLADDRSTSSLNSSSSDQVFQNETLNRMKDNKEKTPNINVSDLSNDGLLAAMANFTQNMVSEKSVKERLREQILAGEFHKKGSLPRGSSVDSSSSQMSVSSPVSGDLQRTSNLVTNTPQSEQQPNVNASDVLVETVSQMSPNDGLNHTMSSVLPEGAVNDQ--PSNMPITSVDEVLEIQKALEKLDLDREIS-----EVIRTVDVPAVIPVQPTKPEL---KPTKPKVLPTVKPSYVKPFVCDVKGCTYSAMTKDALMKHLVKTHNYTEDMLAQMKDQFN-VAPFRCQK--CSKAFTRNSNLKAHYISIHNYSQEEVKKMKIRPQSSQRLLESDKGSPCSVPEVPRTVKNTPVVDARQPPKDVTCPSGSMRHDTVKTPHCIPPPFVPQSAFVPQSRSLAAGTPTVNQMAVQPSVIMSSHSSVTQRIDQNANGWFPTPTPVPAQAQLSPLKEILPIAPFTQNPSALLHKVNLPLDKKPKPSKPKVAKPKESPKKIKEKKPEADDAFSPYRPYRCVHQGCVAAFTIQHNLILHYKAVHQSALPKFEINSHDEQNDEEAEDMDRVEEREDKLDVDVKEVDEFRCQVKDCSSIFQTVPDMLQHYLQLHKLPLEKAGAMMCSINLGRFQCDQSECSETFTGFWKYIRHVDKKHKETQLSKVN---AVAGVFRCPMEGCEGAYSTRSNLLRHTMKKHQEVYKRLLMSPRGTKTGVKLGRPRKFQSHVVEKENRAMNKKSIKK-----PILKKKKPNTNN-WTKYGKP---------------ILKTQEEASAMCTKRLQLQYACMIKGCETVTSSERNIMKHYLQHGLPKQYLEEQRSNFIYCKKIPRSKYKRIASRSDDTDKSEESSIETTENEEVAEPGQSESE------------------FSKPTSGKESTEDPDLSDGKPSTDTCSEISVVVKRRRGRPRKGNVKERKPTGPKRMTRQGIAGSSSVSYADLNSDSTSSSTTLIQEEASSKNTPLSSFKPMGFEVSFLQFLQESKTSQKRKATV--PLNGNAHKRMTTFQLKTATVVCKRADAELRPREALKLVEFKNPQKLTSLSNVKFEVQKVFTNVLEILLKQLQEMRPTVILQKEK-------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "E7FBU0-1", "uniprot_id": "E7FBU0_DANRE", "id": "E7FBU0-1", "name": "", "aln": "MAEEEG-----------SANEAVALKHKFQDLISELKRSSESTLDASNSFCQDFCQILMHHGCQWRPDEDLLPLLELYTAAIMCCAEASPFLSPECEHVTDVLNKLSWSCLNLLLSFSEQIPGALWEKFQTSVKMAHGILQAHGNSQLQALLTLAEDNGIWSNATLCSILSNDLPNVERVHEFLSREGAELLHMRIKHLIKEKDMEKAARLAKTCAEFPEFGGKKNFRQIYLVCLCEITPQQELMHEIKEVDCKEALDMICNLESEEDEKGALSLCTAFFKRQLLSGDAYCAWELTLFWSKLLIRLE-SKQAFLEQCRLLARLSESVYHILLLIKVIQAEVDTDGLSVCIEMCIQALKMGVHDNEDCNITICKTISCLLPLDLEVKQACQLTEFLIKPSLESYYAVETLFNEPDQKLDQEDPPILNSLRCDLLLALKIKWPFDPEFWDWKTLKRQCLALMGQEATAILSSDKFTDSDDNEF------HDLDEKY--FQHFTDNPSYELFEVGTERKKKKNEFKKVKEKGFVSARFRNWQAYMQYCVLCDKEFLGHRIVKHALKHVQDGVFRCPICAKTFDSRTVLEPHVASHVKQSCSERLAAMGVSKKRTDPKLTPASSTLKKEEHYSDTAAKVSQENTCNNNLYTSIGSTSTDVKSKTKSSSSSTSSSSSPKQGNPIRDVNNTKDCCCPVTSCQKVFKYFRNLVAHVKAHKNEQEATDFLQLQSRKAMCQYCHRQFVNLTHLNDHVQMHSGDKPYFCVQLGCNCRFSSHAELLMHRKLHAEFQAQCAYPNCERIFNETYLLYDHEAQHYLTFPCKSHNCDKVFYTLAELDLHQRGHAKQVDHSAIDRRSHLHLEVAPQACPASELPQNQ--------------------------IKDFTPVEIKCSVQNIAGTTQDSTVQPEHLVLHTAQLKETENNSETSAVEPESTTSHCPQKSKRLESCYVKLKPIPIKFNDAVYLN----------TLKNADT-------ETQALLKDKKLFSFIKIPLKPPTPKSSLAVTKENREE----------------------------------------------------------HLTHICPFETCTRKYSTSKSLSRHVKNVHAEAFEEWKLSKKYKRIAQV-----------------------------ASKKSSSKHMTTNMPTPLLVKKWKGCSQKTERVNLQESAIQSPSSIFTNHVNMQSIGTKFCSQFENPPSAASTNQSGLMQLPDAQAWALPSMESLSSGFSEHGSYSSTILSENQHTNPSYHSDTILDYPSASSYDDIIPLPGNAHAPSGVMNEA-SKYVSSSLRVLHALNGDQTCDLSQVESSVNLEDISISNDLHAGALSGQNVSLYFPSEASSVSMQSMENSNKEMSSECTDAAFASEIKCMSDILNPNFKESSEDFFGATPVN--DDKTPDDFCNHEMALEGPEGITSDDQTVLDSGENRKCKKIKSSKRTKWPAIIQDGKVICCR-CYREFSSTKSLGGHLSKRSQCKPVDEIDLTADLPVSFLDFLNDPDIS------------------------------------------------------------------------------------------------------TVQMP-----LPANDILEDNHKSFIYAPSESSTFNDNTLTSVHG-TESIPNINANEPSQD----------------------------------------------------------------HSEIATNPNLFNSPVSNTATEMIADTEIIPENAGEDG--------------------------IILEIERALQRLDLVDVLSD---KSVPESTNLQELSSKSDTRNDQ---QNTIKDPVQTEQKSVLKPFKCKEDACTYGAMTKEALFKHFSRVHDYSDERINEIKKNPDRLAPYGCHL--CSKTFTRTTGLKIHYKNVHHFSKDEISVLKIGLGFRKPKKPAPESETVHSALIDKQANKSEKIQHQVDPKLTVSTVKSNVDGKPKIVSKKKKQATKSSLTVGTTKSCKTTEETQKNVGN-----LDRLSTTCIKLEAPAQNAESHASDLNHPGIFGAQELSGLSSPHLFNKVNATNEEYATPQFFGQIGTKSSVTEDTQEKTMAVGNTDCGDSVDVYRPYRCIHEGCVAAFSIQQNLILHYRAMHQSECD---------------------EKNSAKATDGVFPVQEYRCQVKQCSKVVSKVTSLLKHYLLLHRCTLEKASALLSGVEVGTFQCDQSKCSAHFTCHLKYIDHIKNDHKAIKVSVDGDFESVNLTFGCQFKGCDRVYTTKSNLLRHLMKKHDATFETMKAKQEHVGDSVQTKKSSANPNSNNGKENIAKDKTKTKK-----KSSKKKEDKAQSQRVTLEKP---------------ALKSNEEASALCTQTFPLQYPCMIKNCDSVMNDERNILHHYTTHGLTEQYIEDQRSQFIFCIKS-----------SEIPAADSTSQNVEVKEAQISEAQNPNSD------------------VSSQDVGPEPAKEVEVN------EAVTAVPPVVKRKRGRPRKSDCRNKVSVERKQSLRN---CSDEHVKCMLKVSGSILRASNSQGNHRKNKVALKLYKSSKFQTTVLKFSQNPLSNPSK-------------------RLRKLKPIIRTKDQVKR------VVNFRNPLKIERVNNVKIVMYKNQSPGSRLLLKQLQDMQPRVILEKRLHS-----------------------", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "**::*. * ::*:: * .: ::: :* ::** *:.:. *: .:: **:**:* .*: . .:* * *:.:** *. :*::*: ** :***.:. ::.. *::*:* *::** : * ..* * *:*.: *:*.*..* :***.: :.*:***: **. ** **:*:*:* .:*: *** *:: .*: * *:* :***** :*. ::.*:.:***::**:******:: :**.*: **:**:.**: . * **********.:* *:* * * :*::** :: *:::*:*::::**.*::* **..*:*:*::**:: :. . : ::********* *****:****:***::*::::***** *:*:**** * *: : *****:***.** :******:*:**:***:**.***:**: : * *::.*.: : . :. .. * :.:::: *:*:::::**:**************:************:** .* :** : **** :.*::: : ***: *** *..****** :: * .. : : . * . ...... .. . : *** *:* ****:**:**** * :.::*. **::** * :****:*:**.: *****:***.* ***:*:*: *:. *.* :**: *:* * *:*:* :* * :** ::* ********* *:.** .*.**: : .*:: * .* : . . * . :. * : . .. : : * . * : . . : : * :. : . . : . * * *** *.: :*: :*:* .*.: : :*: :* : : : .. :. . : *. . . : .. .: . .: . :. . ... . . . : .. : . * .: .. . . . : . : * : .. * : : . . . : : : .: .:.: . : . *:::. . . * . * . : . .. :. .:*. : .. . . . : . : . .. : :: ::. : :..: : . : . . : .. : * : : :* ..*:.*.* * . .: . : : : . : *** *. ..*.*.****:**:** : *:*: : : ::*.: .**: * *:*:***.:.*: * :*::: :*: :** : . : . . . . .. : . : : : . . *. : . **** *:*:**.***:**:******:*:*:* .. : :.*:****.:** :.. :..:::**: **. . *: :: ..:::* * *** :*. ** . .*: *:. .* : : * :**: *:*:****** ::**: .: . . : . . *.. . *. :**: : :. .. : :*:.::* : **. : **.****.* :* ..* **::** * *.. : .::*. :* : . . .. :. : : . .: .:. .. : : . : ..:: . :. .: : . . .: : . . :*. *:.:.*:* ::. . .: : . . . .*:* ** :: .***: : * . .::*****:*:* * *:* ", "identical_positions": 498, "similar_positions": 639, "identity": "17.75%" }, { "cls_id": "homologset.agr.MGI:1353424", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P62077-1", "uniprot_id": "TIM8B_MOUSE", "id": "P62077-1", "name": "Mitochondrial import inner membrane translocase subunit Tim8 B", "aln": "MAELG--------EADEAELQRLVAAEQQKAQFTAQVHHFMELCWDKCVEKPG-SRLDSRTENCLSSCVDRFIDTTLAITGRFAQIVQK--GGQ-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P62078-1", "uniprot_id": "TIM8B_RAT", "id": "P62078-1", "name": "Mitochondrial import inner membrane translocase subunit Tim8 B", "aln": "MAELG--------EADEAELQRLVAAEQQKAQFTAQVHHFMELCWDKCVEKPG-SRLDSRTENCLSSCVDRFIDTTLAITGRFAQIVQK--GGQ-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9Y5J9-1", "uniprot_id": "TIM8B_HUMAN", "id": "Q9Y5J9-1", "name": "Mitochondrial import inner membrane translocase subunit Tim8 B", "aln": "MAELG--------EADEAELQRLVAAEQQKAQFTAQVHHFMELCWDKCVEKPG-NRLDSRTENCLSSCVDRFIDTTLAITSRFAQIVQK--GGQ-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9Y1A3-1", "uniprot_id": "TIM8_DROME", "id": "Q9Y1A3-1", "name": "Mitochondrial import inner membrane translocase subunit Tim8", "aln": "MSDFEN------LSGNDKELQEFLLIEKQKAQVNAQIHEFNEICWEKCIGKPS-TKLDHATETCLSNCVDRFIDTSLLITQRFAQMLQKRGGGDL", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P57744-1", "uniprot_id": "TIM8_YEAST", "id": "P57744-1", "name": "Mitochondrial import inner membrane translocase subunit TIM8", "aln": "MSSLSTSDLASLDDTSKKEIATFLEGENSKQKVQMSIHQFTNICFKKCVESVNDSNLSSQEEQCLSNCVNRFLDTNIRIVNGLQNTR--------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*:.: . .. *: :: *:.* :. .:*.* ::*:.**: . . ..*. * ***.**:**:**.: *. : : ", "identical_positions": 21, "similar_positions": 34, "identity": "22.11%" }, { "cls_id": "homologset.agr.MGI:1353425", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P04950-1", "uniprot_id": "OPS3_DROME", "id": "P04950-1", "name": "Opsin Rh3", "aln": "------------------------------------MESGNVSSSLFGNVSTALRPEARLS--AETRLLGWNVPP--------------------EELRHIPEHWLTYPEPPESMNYLLGTLYIFFTLMSMLGNGLVIWVFSAAKSLRTPSNILVINLAFCDFMMMVK-TPIFIYNSFHQGYALGHLGCQIFGIIGSYTGIAAGATNAFIAYDRFNVITRPMEGK--MTHGKAIAMIIFIYMYATPWVVACYTET-WGRFVPEGYLTSCTFDYLTDNFDTRLFVACIFFFSFVCPTTMITYYYSQIVGHVFSHEKALRDQAKKMNVESLRSNVDKNKETAEIRIAKAAITICFLFFCSWTPYGVMSLIGAFGDKTLLTPGATMIPACACKMVACIDPFVYAISHPRYRMELQKRCPWLALNEKAPESSAVASTSTTQEPQQTTAA-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P08255-1", "uniprot_id": "OPS4_DROME", "id": "P08255-1", "name": "Opsin Rh4", "aln": "------------------------------------MEP------LCNASEPPLRPEARSSGNGDLQFLGWNVPP--------------------DQIQYIPEHWLTQLEPPASMHYMLGVFYIFLFCASTVGNGMVIWIFSTSKSLRTPSNMFVLNLAVFDLIMCLK-APIFIYNSFHRGFALGNTWCQIFASIGSYSGIGAGMTNAAIGYDRYNVITKPMNRN--MTFTKAVIMNIIIWLYCTPWVVLPLTQF-WDRFVPEGYLTSCSFDYLSDNFDTRLFVGTIFFFSFVCPTLMILYYYSQIVGHVFSHEKALREQAKKMNVESLRSNVDKSKETAEIRIAKAAITICFLFFVSWTPYGVMSLIGAFGDKSLLTPGATMIPACTCKLVACIDPFVYAISHPRYRLELQKRCPWLGVNEKSGEISSAQST-TTQEQQQTTAA-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P91657-1", "uniprot_id": "OPS5_DROME", "id": "P91657-1", "name": "Opsin Rh5", "aln": "--------------------------------------------MHINGPSGPQAYVNDSLGDGSVFPMGHGYPA--------------------EYQHMVHAHWRGFREAPIYYHAGFYIAFIVLMLSSIFGNGLVIWIFSTSKSLRTPSNLLILNLAIFDLFMCTN-MPHYLINATVGYIVGGDLGCDIYALNGGISGMGASITNAFIAFDRYKTISNPIDGR--LSYGQIVLLILFTWLWATPFSVLPLFQI-WGRYQPEGFLTTCSFDYLTNTDENRLFVRTIFVWSYVIPMTMILVSYYKLFTHVRVHEKMLAEQAKKMNVKSLSANANADNMSVELRIAKAALIIYMLFILAWTPYSVVALIGCFGEQQLITPFVSMLPCLACKSVSCLDPWVYATSHPKYRLELERRLPWLGIREKHATSGTSGGQESVASVSGDTLALSVQN--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P06002-1", "uniprot_id": "OPS1_DROME", "id": "P06002-1", "name": "Opsin Rh1", "aln": "--------------------------------------MES-----FAVAAAQLGPHFAPLS---NGSVVDKVTP--------------------DMAHLISPYWNQFPAMDPIWAKILTAYMIMIGMISWCGNGVVIYIFATTKSLRTPANLLVINLAISDFGIMITNTPMMGINLYFETWVLGPMMCDIYAGLGSAFGCSSIWSMCMISLDRYQVIVKGMAGRP-MTIPLALGKIAYIWFMSSIWCLAPAFG--WSRYVPEGNLTSCGIDYLERDWNPRSYLIFYSIFVYYIPLFLICYSYWFIIAAVSAHEKAMREQAKKMNVKSLRSSE-DAEKSAEGKLAKVALVTITLWFMAWTPYLVINCMGLF-KFEGLTPLNTIWGACFAKSAACYNPIVYGISHPKYRLALKEKCPCCVFGKVDDGKS-SDAQSQATASEAESKA-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P08099-1", "uniprot_id": "OPS2_DROME", "id": "P08099-1", "name": "Opsin Rh2", "aln": "--------------------------------------MERSHLPETPFDLAHSGPRFQAQSSG-NGSVLDNVLP--------------------DMAHLVNPYWSRFAPMDPMMSKILGLFTLAIMIISCCGNGVVVYIFGGTKSLRTPANLLVLNLAFSDFCMMASQSPVMIINFYYETWVLGPLWCDIYAGCGSLFGCVSIWSMCMIAFDRYNVIVKGINGTP-MTIKTSIMKILFIWMMAVFWTVMPLIG--WSAYVPEGNLTACSIDYMTRMWNPRSYLITYSLFVYYTPLFLICYSYWFIIAAVAAHEKAMREQAKKMNVKSLRSSE-DCDKSAEGKLAKVALTTISLWFMAWTPYLVICYFGLF-KIDGLTPLTTIWGATFAKTSAVYNPIVYGISHPKYRIVLKEKCPMCVFGNTDEPKPDAPASDTETTSEADSKA-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "O01668-1", "uniprot_id": "OPS6_DROME", "id": "O01668-1", "name": "Opsin Rh6", "aln": "-------------------------------------------------MASLHPPSFAYMRDGRNLSLAESVPA--------------------EIMHMVDPYWYQWPPLEPMWFGIIGFVIAILGTMSLAGNFIVMYIFTSSKGLRTPSNMFVVNLAFSDFMMMFTMFPPVVLNGFYGTWIMGPFLCELYGMFGSLFGCVSIWSMTLIAYDRYCVIVKGMARKP-LTATAAVLRLMVVWTICGAWALMPLFG--WNRYVPEGNMTACGTDYFAKDWWNRSYIIVYSLWVYLTPLLTIIFSYWHIMKAVAAHEKAMREQAKKMNVASLRNSEADKSKAIEIKLAKVALTTISLWFFAWTPYTIINYAGIF-ESMHLSPLSTICGSVFAKANAVCNPIVYGLSHPKYKQVLREKMPCLACGKDD---LTSDSRTQATAEISESQA-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q8R456-1", "uniprot_id": "OPN4_RAT", "id": "Q8R456-1", "name": "Melanopsin", "aln": "---------------------MN--SPSESRVPSSLTQDPSFTASPALLQGIWNSTQN-ISVRVQLLSVSPTTP----------------------GLQAAAWVPFPTVDVPDHAHYTLGTVILLVGLTGMLGNLTVIYTFCRNRGLRTPANMLIINLAVSDFLMSFTQAPVFFASSLYKKWLFGETGCKFYAFCGAVFGIVSMITLTAIAMDRYLVITRPLATIGMRSKRRTALVLLGVWLYALAWSLPPFFG--WSAYVPEGLLTSCSWDYVTFTPLVRAYTMLLFCFVFFLPLLIIIFCYIFIFRAIRETGRACEGCGES--PLR-RRQWQR--LQSEWKMAKVALIVILLFVLSWAPYSTVALVGFAGYSHILTPYMSSVPAVIAKASAIHNPIIYAITHPKYRAAIAQHLPCLGVLLGVSGQ--RSHPSLSYRSTHRSTLSSQSSDLSWISGQKRQES--------LGSESEVGWTDTETTAAWGAAQQASGQSFCSHDLEDGEVKAP----------------------SSPQEQKSKTPKT-----------KRHLPSLDR--------------------------------RM------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9QXZ9-1", "uniprot_id": "OPN4_MOUSE", "id": "Q9QXZ9-1", "name": "Melanopsin", "aln": "---------------------MD--SPSGPRVLSSLTQDPSFTTSPA-LQGIWNGTQN-VSVRAQLLSVSPTTS----------------------AHQAAAWVPFPTVDVPDHAHYTLGTVILLVGLTGMLGNLTVIYTFCRNRGLRTPANMFIINLAVSDFLMSVTQAPVFFASSLYKKWLFGETGCEFYAFCGAVFGITSMITLTAIAMDRYLVITRPLATIGRGSKRRTALVLLGVWLYALAWSLPPFFG--WSAYVPEGLLTSCSWDYMTFTPQVRAYTMLLFCFVFFLPLLIIIFCYIFIFRAIRETGRACEGCGES--PLRQRRQWQR--LQSEWKMAKVALIVILLFVLSWAPYSTVALVAFAGYSHILTPYMSSVPAVIAKASAIHNPIIYAITHPKYRVAIAQHLPCLGVLLGVSGQ--RSHPSLSYRSTHRSTLSSQSSDLSWISGRKRQES--------LGSESEVGWTDTETTAAWGAAQQASGQSFCSQNLEDGELKAS----------------------SSPQVQRSKTPKVPGPSTCRPMKGQGARPSSLRG---------------------------DQKGRLAVCTGLSECPHPHTSQFPLAFLEDDVTLRHL-----------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9UHM6-1", "uniprot_id": "OPN4_HUMAN", "id": "Q9UHM6-1", "name": "Melanopsin", "aln": "---------------------MN--PPSGPRVPPSPTQEPSCMATPA-PPSWWDSSQSSISSLGRLPSISPTAP----------------------GTWAAAWVPLPTVDVPDHAHYTLGTVILLVGLTGMLGNLTVIYTFCRSRSLRTPANMFIINLAVSDFLMSFTQAPVFFTSSLYKQWLFGETGCEFYAFCGALFGISSMITLTAIALDRYLVITRPLATFGVASKRRAAFVLLGVWLYALAWSLPPFFG--WSAYVPEGLLTSCSWDYMSFTPAVRAYTMLLCCFVFFLPLLIIIYCYIFIFRAIRETGRALQTFGAC--KGNGESLWQRQRLQSECKMAKIMLLVILLFVLSWAPYSAVALVAFAGYAHVLTPYMSSVPAVIAKASAIHNPIIYAITHPKYRVAIAQHLPCLGVLLGVSRR--HSRPYPSYRSTHRSTLTSHTSNLSWISIRRRQES--------LGSESEVGWTHMEAAAVWGAAQQANGRSLYGQGLEDLEAKAP----------------------PRPQGHEAETPGKT----------KGLIPSQDP--------------------------------RM------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q1JPS6-1", "uniprot_id": "OPN4L_DANRE", "id": "Q1JPS6-1", "name": "Melanopsin-like", "aln": "---------------------MS--HHSSWRGHHCAPGDINCTAGFKESLGSRN------YKLLHVPVHGPTHS-----------------------HHHDPPHPFPTVDVPDHAHYIIGSVILIVGITGVIGNALVVYVFCRSRTLRTAGNMFIVNLAVADFLMSVTQSPVFFAASLHRRWVFGERPCELYAFCGALFGICSMMTLTAIAADRCLAITQPLALVSRVSRRKAGAVLVVVWLYSLGWSLPPFFG--WSAYVPEGLQTSCSWDYMTFTPSVRAYTILLFVFVFFIPLGIIGSCYFAIFQTIRAAGKEIRELDCG----ETHKVYER--MQNEWKMAKVALVVIVLFIISWSPYSVVALTATAGYSHFLTPYMNSVPAVIAKASAIHNPIIYAITHPKYRVAIARYIPVLRPILRVKEKDLRSSFSSGSVSSRRPTLTSQCSLGVSMGNAARANGRWGKTRLSSASDSDSCWTESEADGSSVSSLTFGRRVSTEISTDTVILS------------------------SGSSVSNASGQ---KSER----AHKVISVPVPS---------------------------------ITFETDAADGES---LSDGKALLGGN-----------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q2KNE5-1", "uniprot_id": "OPN4A_DANRE", "id": "Q2KNE5-1", "name": "Melanopsin-A", "aln": "--------------------MMSGAAHSVRKGISCPTQDPNCTR-IVESLSAWNDSVMSAYRLVDLPPTTTTTTS--------------------VAMVEESVYPFPTVDVPDHAHYTIGAVILTVGITGMLGNFLVIYAFSRSRTLRTPANLFIINLAITDFLMCATQAPIFFTTSMHKRWIFGEKGCELYAFCGALFGICSMITLMVIAVDRYFVITRPLASIGVLSQKRALLILLVAWVYSLGWSLPPFFG--WSAYVPEGLLTSCTWDYMTFTPSVRAYTMLLFIFVFFIPLIVIIYCYFFIFRSIRTTNEAVGKINGDN-KRDSMKRFQR--LKNEWKMAKIALIVILMYVISWSPYSTVALTAFAGYSDFLTPYMNSVPAVIAKASAIHNPIIYAITHPKYRLAIAKYIPCLRLLLCVPKRDLHS-FHSSLMSTRRSTVTSQSSD---MSGRFRRTS-TGKSRLSSASDSESGWTDTEADLSSMSSRPASRQVSCDISKDTAEMPDFKPCNSSSFKSKLKSHDSGIFEKSSSDVDDVSVAGIIQPDRTLTNAGDITDVPISRGAIGRIPSIVITSESSSLLPSVRPTYRISRSNVSTVGTNPARRDSRGGVQQGAAHLSNAAETPESGHIDNHRPQYL", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VTU7-1", "uniprot_id": "Q9VTU7_DROME", "id": "Q9VTU7-1", "name": "", "aln": "MEAIIMTTLPNLTTDAGDSSFWLTGALSLSEMLANSSHSHSTGSTTSTAGSSATESSAVNVGKDHDKHVNDSVSTGLSNYSNYPSYIHYRDKYDLSYIAKVNPFWLQFEPPKSSTFLIMAALYCLISVVGCVGNAFVIFMFANRKSLRTPANILVMNLAICDFLMLIK-CPIAIYNNIKEGPALGDIACRLYGFVGGLSGTCAIGTLTAIALDRYNVVVHPLQPLRRCSRLRSYLIILLIWCYSFLFAVMPALDIGLSVYVPEGFLTTCSFDYLNKEMPARIFMALFFVAAYCIPLTSIVYSYFYILKVVFTASRIQSNKDKA---------------KTEQKLAFIVAAIIGLWFLAWSPYAIVAMMGVFGLERHITPLGSMIPALFCKTAACVDPYLYAATHPRFRVEVRMLFYGRGVLRRVSTTRSSYMTRSRSSFTHRLRTSTTGEGGMGDHRMENYLMNNNLMMVPEETEENEEIVVVAEINNSISSVMEQSKF-------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . . ** *:: * : ***..*::::***. *: : . * * * ::. *. * : : *. ** .: . : : : . : : . : *** *:* **. * : : * * * :. : . * ::* ::. :*:** : . ::* . . .* : :* :*. :**::: : ", "identical_positions": 42, "similar_positions": 65, "identity": "6.52%" }, { "cls_id": "homologset.agr.MGI:1353427", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D4A7V9-1", "uniprot_id": "E2AK4_RAT", "id": "D4A7V9-1", "name": "eIF-2-alpha kinase GCN2", "aln": "MAGGRGAAGRGPAEPQESYSQRQDHELQALEAIYGSDFQDLRPDARGRVREPPEINLVLYPQG--LAGEEVYVQVELRVKCPPTYPDVVPEIELKNTKGLSNESVNLLKSHLEELAKKQCGEVMIFELAHHVQSFLSEHNKPP-PKSFHEEMLERQAQEKQQRLLEARQKEEQEQREILHEIQKRKEEIKEEKKRKEMAKQERLEITSLTNQDHASKRDPAGHRAAAFLHGGSPDFVGNGKARAHSSGRSRRERQYSVCSGEASPGSCDILYFCVGSADQLMVHKGKCVGS-DEQLGKVVYNALETATGSFVLLYEWVLQWQKKMGPCLTS--------QEKEKIDKCKKQIQGAETEFSSLVKLSHPNIVRYFAMNSREEKDS-----IVVDILAEHISGISLAAHLSHSGPVPMHQLRKYTAQLLAGLDYLHRNSVVHKVLSTASVLVDAEG------------TVKITDYSISKRLADICKEDVFEQTRVRFSDSALPYKTGKKG---DVWRLGLLLLSLSQGQECEE-----YPVTIPSDLPADFQDFLKKCVCLDDKERWSPQQLLKHSFINPQPKMPLVEQSPEDSGGQDYIETIIPSNQLPS---------------------AAFFTETQRQFSRYFIEFEELQLLGKGAFGAVIKVQNKLDGCCYAVKRIPINPASR-QFRRIKGEVTLLSRLHHENIVRYYNAWIERHERPAVPGTPPPDYIPQAQNSSATGGKASGDTEELGSVEAAAPPPILSSSVEWSTSAERSNSARFPVTGQDSSSDEED-EDERDGVFSQSFLPASDSDSDIIFDNEDENSKSQNQDEDCNEKDSRHEI---------EPSVTTEAVHYLYIQMEYCEKSTLRDTIDQG-LFRDTSRLWRLFREILDGLAYIHEKGMIHRDLKPVNIFLDSDDHVKIGDFGLATDHLAFNAEGKQDDQAGDHVIKSDPSGHLTGMVGTALYVSPEVQG-STKSAYNQKVDLFSLGIILFEMSYHPMVTASERIFVLNQLRDPTSPKFPDDFEDGEHTKQKSVISWLLNHDPAKRPTAMELLKSELLPPPQMEESELHEVLHHTLANTDGKAYRTMMSQLFCQHSSPAIDYTYDS----------DILKGNFLIRTAKIQQLVCETIVRVFKRHGAVQLCTPLLLP---RNRQIYEHNEAALFMDHSGMLVMLPFDLRVPFARYVARNNILNLKRYCIERVFRPRKLDR--FHPKELLECAFDIVTSTAN-SSLPTAETIYTIYEVIQEFPALQERNYSIYLNHTMLLKAILLHCGIPEDKLSQVYVILYDAVTEKLTRREVEAKFCNLSLSSNSLCR------LYKFIEQKGDLQDLTPTINSLIKQKTGIAQLVKYSLKDLEEVVGLLKKLGVKLQVSINLGLVYKVQQHN--GIIFQFLAFSKRRQRVVPEILAAGGRYDLLIPKFRGPQALG-------PVPTAVGVSIAIDKIFAAVLNMGEPVT-------------------VSSCDLLVVSAGQMSMSRA-INLTQKLWTAGITAEIMYDWSQSQEELQEYCRHHEITYVALVSDKE---GSHVKVKSFEKERQTEKRVLESDLVDHVMQKLRTKVGD--------------ERNFRDASDNLAVQTLKGSFSNASGLFEIHGTTVVP--TVSVISPEKLSASTRRRHEIQVQTRLQTTLANLHQKSSEIEILAVDLPKETILQFLSLEWDADEQAFNTT--VKQLLSRLPK-QRYLKLVCDEIYNIKVEKKVSVLFLYSYRDDYYRILF---", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9QZ05-1", "uniprot_id": "E2AK4_MOUSE", "id": "Q9QZ05-1", "name": "eIF-2-alpha kinase GCN2", "aln": "MAGGRGASGRGRAEPQESYSQRQDHELQALEAIYGSDFQDLRPDARGRVREPPEINLVLYPQG--LAGEEVYVQVELQVKCPPTYPDVVPEIELKNAKGLSNESVNLLKSHLEELAKKQCGEVMIFELAHHVQSFLSEHNKPP-PKSFHEEMLERQAQEKQQRLLEARRKEEQEQREILHEIQRRKEEIKEEKKRKEMAKQERLEITSLTNQDYASKRDPAGHRAAAILHGGSPDFVGNGKARTYSSGRSRRERQYSVCSGEPSPGSCDILHFSVGSPDQLMVHKGRCVGS-DEQLGKVVYNALETATGSFVLLHEWVLQWQK-MGPCLTS--------QEKEKIDKCKRQIQGAETEFSSLVKLSHPNIVRYFAMNSREEEDS-----IVIDILAEHVSGISLATHLSHSGPVPAHQLRKYTAQLLAGLDYLHSNSVVHKVLSASSVLVDAEG------------TVKITDYSISKRLADICKEDVFEQARVRFSDSALPYKTGKKG---DVWRLGLLLLSLSQGQECGE-----YPVTIPSDLPADFQDFLKKCVCLDDKERWSPQQLLKHSFINPQPKLPLVEQSPEDSGGQDYIETVIPSNQLPS---------------------AAFFSETQKQFSRYFIEFEELQLLGKGAFGAVIKVQNKLDGCCYAVKRIPINPASR-HFRRIKGEVTLLSRLHHENIVRYYNAWIERHERPAVPGTPPPDCTPQAQDSPATCGKTSGDTEELGSVEAAAPPPILSSSVEWSTSAERSTSTRFPVTGQDSSSDEED-EDERDGVFSQSFLPASDSDSDIIFDNEDENSKSQNQDEDCNQKDGSHEI---------EPSVTAEAVHYLYIQMEYCEKSTLRDTIDQG-LFRDTSRLWRLFREILDGLAYIHEKGMIHRDLKPVNIFLDSDDHVKIGDFGLATDHLAFTAEGKQDDQAGDGVIKSDPSGHLTGMVGTALYVSPEVQG-STKSAYNQKVDLFSLGIIFFEMSYHPMVTASERIFVLNQLRDPTSPKFPDDFDDGEHTKQKSVISWLLNHDPAKRPTAMELLKSELLPPPQMEESELHEVLHHTLANIDGKAYRTMMSQIFCQHISPAIDYTYDS----------DILKGNFLIRTAKIQQLVCETIVRVFKRHGAVQLCTPLLLP---RNRQIYEHNEAALFMDHSGMLVMLPFDLRVPFARYVARNNILNLKRYCIERVFRPRKLDR--FHPKELLECAFDIVTSTTN-SSLPTAETIYTIYEIIQEFPALQERNYSIYLNHTMLLKAILLHCGIPEDKLSQVYVILYDAVTEKLTRREVEAKFCNLSLSSNSLCR------LYKFIEQKGDLQDLTPTINSLIKQKTGVAQLVKYSLKDLEDVVGLLKKLGVKLQVSINLGLVYKVQQHT--GIIFQFLAFSKRRQRVVPEILAAGGRYDLLIPKFRGPQTVG-------PVPTAVGVSIAIDKIFAAVLNMEEPVT-------------------VSSCDLLVVSVGQMSMSRA-INLTQKLWTAGITAEIMYDWSQSQEELQEYCRHHEITYVALVSDKE---GSHVKVKSFEKERQTEKRVLESDLVDHVMQKLRTKVGD--------------ERNFRDASDNLAVQTLKGSFSNASGLFEIHGTTVVP--NVIVLAPEKLSASTRRRHEIQVQTRLQTTLANLHQKSSEIEILAVDLPKETILQFLSLEWDADEQAFNTT--VKQLLSRLPK-QRYLKLVCDEIYNIKVEKKVSVLFLYSYRDDYYRILF---", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9P2K8-1", "uniprot_id": "E2AK4_HUMAN", "id": "Q9P2K8-1", "name": "eIF-2-alpha kinase GCN2", "aln": "MAGGRGAPGRGRDEPPESYPQRQDHELQALEAIYGADFQDLRPDACGPVKEPPEINLVLYPQG--LTGEEVYVKVDLRVKCPPTYPDVVPEIELKNAKGLSNESVNLLKSRLEELAKKHCGEVMIFELAYHVQSFLSEHNKPP-PKSFHEEMLERRAQEEQQRLLEAKRKEEQEQREILHEIQRRKEEIKEEKKRKEMAKQERLEIASLSNQDHTSKKDPGGHRTAAILHGGSPDFVGNGKHRANSSGRSRRERQYSVCNSEDSPGSCEILYFNMGSPDQLMVHKGKCIGS-DEQLGKLVYNALETATGGFVLLYEWVLQWQKKMGPFLTS--------QEKEKIDKCKKQIQGTETEFNSLVKLSHPNVVRYLAMNLKEQDDS-----IVVDILVEHISGVSLAAHLSHSGPIPVHQLRRYTAQLLSGLDYLHSNSVVHKVLSASNVLVDAEG------------TVKITDYSISKRLADICKEDVFEQTRVRFSDNALPYKTGKKG---DVWRLGLLLLSLSQGQECGE-----YPVTIPSDLPADFQDFLKKCVCLDDKERWSPQQLLKHSFINPQPKMPLVEQSPEDSEGQDYVETVIPSNRLPS---------------------AAFFSETQRQFSRYFIEFEELQLLGKGAFGAVIKVQNKLDGCCYAVKRIPINPASR-QFRRIKGEVTLLSRLHHENIVRYYNAWIERHERPAGPGTPPPDSGPLAKDDRAARGQPASDTDGLDSVEAAAPPPILSSSVEWSTSGERSASARFPATGPGSSDDEDDDEDEHGGVFSQSFLPASDSESDIIFDNEDENSKSQNQDEDCNEKNGCHES---------EPSVTTEAVHYLYIQMEYCEKSTLRDTIDQG-LYRDTVRLWRLFREILDGLAYIHEKGMIHRDLKPVNIFLDSDDHVKIGDFGLATDHLAFSADSKQDDQTGD-LIKSDPSGHLTGMVGTALYVSPEVQG-STKSAYNQKVDLFSLGIIFFEMSYHPMVTASERIFVLNQLRDPTSPKFPEDFDDGEHAKQKSVISWLLNHDPAKRPTATELLKSELLPPPQMEESELHEVLHHTLTNVDGKAYRTMMAQIFSQRISPAIDYTYDS----------DILKGNFSIRTAKMQQHVCETIIRIFKRHGAVQLCTPLLLP---RNRQIYEHNEAALFMDHSGMLVMLPFDLRIPFARYVARNNILNLKRYCIERVFRPRKLDR--FHPKELLECAFDIVTSTTN-SFLPTAEIIYTIYEIIQEFPALQERNYSIYLNHTMLLKAILLHCGIPEDKLSQVYIILYDAVTEKLTRREVEAKFCNLSLSSNSLCR------LYKFIEQKGDLQDLMPTINSLIKQKTGIAQLVKYGLKDLEEVVGLLKKLGIKLQVLINLGLVYKVQQHN--GIIFQFVAFIKRRQRAVPEILAAGGRYDLLIPQFRGPQALG-------PVPTAIGVSIAIDKISAAVLNMEESVT-------------------ISSCDLLVVSVGQMSMSRA-INLTQKLWTAGITAEIMYDWSQSQEELQEYCRHHEITYVALVSDKE---GSHVKVKSFEKERQTEKRVLETELVDHVLQKLRTKVTD--------------ERNGREASDNLAVQNLKGSFSNASGLFEIHGATVVP--IVSVLAPEKLSASTRRRYETQVQTRLQTSLANLHQKSSEIEILAVDLPKETILQFLSLEWDADEQAFNTT--VKQLLSRLPK-QRYLKLVCDEIYNIKVEKKVSVLFLYSYRDDYYRILF---", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A0B4KHX7-1", "uniprot_id": "A0A0B4KHX7_DROME", "id": "A0A0B4KHX7-1", "name": "non-specific serine/threonine protein kinase", "aln": "---------MADEKAKESFRERQAQELEVIKSIFGCDVEDLRPQANPSLWKPTDIRIQLTPLRDSSNGLETYVCTKLHVTCPSKYPKLPPKISLEESKGMSDQLLEALRNQLQAQSQELRGEVMIYELAQTVQAFLLEHNKPP-KGSFYDQMLQDKQKRDQELQDIQRQRESLQRQTLIDEVERRKEMFKTEAKRRGEPRRSMSESNPRHPSSSESSENSSPYYRGHIYPSKCLDHRNTETLYFHKMGR--------------------------------QIQRGCCVGEGHSQRGCIAYTGIDMHCGQLLYITEWNIKYSQLEQPCIGGGKCHWSSESKCMGSHRVDEVMASIEKQVSSLSQLQHKNLVSYECVLCIKRKEG-----LLVYLVQDFLLGTSVFSISSSLG-WCMDGARMVARGVLDALVFLHNKGVSHSHLLDTTVFMDNTG------------NVRVSDFSLVPNLLELLSG---------------AGQSSSCG---DLPALGALVESLMPTN------------------SYEMRDFVDKCNSD---RTLSASELLEHPFLRFYVDNGQQQVMPLPQQQHPNTVQRTGSAMPYQ---------------------IPTLALSQ---SRLRTEFEVLMYLGKGAFGDVLKVRNILDNREYAIKRIPLPARSRQLYKKMTREVELLSRLNHENVVRYFNSWIES----------------------------------VDDADAAEMDKLLGGEWSQSQQDLSVKPAKSPQLGPTLEEDEDE-EDSSSSMWNGYIPNMEDSDSDGIEFVDSNGKVAVYDDE---EQEDSTRG---------KTNSPKPLMQVMYIQMEFCEKCTLRTAIDDN-LFNDTDRLWRLFREIAEGLAHIHQQGIIHRDLKPVNIFLDSHDQIKIGDFGLATTSFLALQAHDAAPAPVN-QITSAEDGTGTGKVGTTLYVAPELTGNASKSVYNQKVDMYTLGIILFEMCQPPFDTSMERAQTIMALRNVSINIPDAMLKDPKYEKTVKMLQWLLNHDPAQRPTAEELLISDLVPPAQLEANELQEMLRHALANPQSKAYKNLVARCLQQESDEVLEHTYHLGSSRAMKSWNSAIIIDDIVSLNPVIEFVKAKVVNLFRKHGAIEVDSPLLSPLSARNSTANANANAVHLMTHSGCVVVLPCDLRTQFARHVTMNSVNLIRRYCVDRVYREERVFN--FHPKQSYDCSFDIIAPTTG-SHLVDAELLSLAFEITSELPRLREKNLAIRMNHTNLLRAILIFCNVPKAQYGALFEGTMDFIESRISRFQFHSSITGIMEKSRTSAQTLMDMLLANFLLTGSRSTVDDSALKSLMRGKGEAASLARGALRELETVVGLAYSLGVKCPIHIWAGLPISFDRASNGGIVWQMTADLKPNRSGHPSVLAIGERYDSMLHEFQKQAQKFNPAMPARGVLSGAGLTFSLDKLVAAVGVEYAKDC-------------------RAIDVGICVCGTRPPLKDV-TYIMRLLWSVGIRCGIVEAASELGDEAQDLARLGALHVILVAEN------GSLRVRSFERERFQERHLTRTELVEFIQKMLRSDGLNGTTVDNFSQLSALGSGDNRSSGGKERERGENGLSTSASNATIKNNYSQLPNLQVTFLTHDKPTANYKRRLENQVAQQMSSTLSQFLKKET-FVVLVVELPPAVVNAIVGAINPREIRKRETEPEINYVIERFSKYKRYISEINEEVVDYLSDAKTPIVALYSISDSYYRVII---", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P15442-1", "uniprot_id": "GCN2_YEAST", "id": "P15442-1", "name": "eIF-2-alpha kinase GCN2", "aln": "--------MSLSHLTLDQYYEIQCNELEAIRSIYMDDFTDLTKRKS-SWDKQPQIIFEITLRS--VDKEPVESSITLHFAMTPMYPYTAPEIEFKNVQNVMDSQLQMLKSEFKKIHNTSRGQEIIFEITSFTQEKLDEFQNVVNTQSLEDDRLQRIKETKEQLEKEEREKQQETIKKRSDEQRRIDEIVQRELEKRQDDDDDLLFNRTTQLDLQPPSEWVASGEAIVFSKTIKAKLPNNSMFKFKAVVNPK------------------------------PIKLTSDIFSFSKQFLVKPYIPPESPLADFLMSSEMMENFYYLLSEIELD--------NSYFNTSNGKKEIANLEKELETVLKAKHDNVNRLFGYTVERMGRNNATFVWKIRLLTEYCNYYPLGDLIQSVGFVNLATARIWMIRLLEGLEAIHKLGIVHKCINLETVILVKDADFGSTIPKLVHSTYGYTVLNMLSRYPNKNGSSVELSPSTWIAPELLKFNNAKPQRLTDIWQLGVLFIQIISGSDIVMNFETPQEFLDSTSMDETLYDLLSKMLNNDPKKRLGTLELLPMKFLRTNIDSTINRFNLVSESVNSNSLELTPGDTITVRGNGGRTLSQSSIRRRSFNVGSRFSSINPATRSRYASDFEEIAVLGQGAFGQVVKARNALDSRYYAIKKIRH---TEEKLSTILSEVMLLASLNHQYVVRYYAAWLEE------------------------------DSMDENVFESTDEESDLSESSSDFEENDLLDQSSIFKNRTNHDLDNSNWDFISGSGYPDIVFENSSRDDENEDLDHDTSSTSSSESQDDTDKESKSIQNVPRRRNFVKPMTAVKKKSTLFIQMEYCENRTLYDLIHSENLNQQRDEYWRLFRQILEALSYIHSQGIIHRDLKPMNIFIDESRNVKIGDFGLAKNVHRSLDILKLDSQNLP-----GSSDNLTSAIGTAMYVATEVLD--GTGHYNEKIDMYSLGIIFFEMIYP-FSTGMERVNILKKLRSVS-IEFPPDFDDNKMKVEKKIIRLLIDHDPNKRPGARTLLNSGWLP--VKHQDEVIKEALKSLSNPSSPWQQQVRESLFNQSYSLTNDILFDN------------SVPTSTPFANILRSQMTEEVVKIFRKHGGIENNAPPRIFP---KAPIYGTQNVYEVLDKGGTVLQLQYDLTYPMARYLSKNPSLISKQYRMQHVYRPPDHSRSSLEPRKFGEIDFDIISKSSSESGFYDAESLKIIDEILTVFPVFEKTNTFFILNHADILESVFNFTNIDKAQRPLVSRMLSQVGFARSFKEVKNELKAQLNISSTALND-------LELFDFRLDFEAAKKRLYKLMIDSPHLKKIEDS-LSHISKVLSYLKPLEVARNVVISPLSNYNSAFYKG-GIMFHAVYDDGSSR----NMIAAGGRYDTLISFFARPSGKKSS-----NTRKAVGFNLAWETIFGIAQNYFKLASGNRIKKRNRFLKDTAVDWKPSRCDVLISSFSNSLLDTIGVTILNTLWKQNIKADMLRDCSSVDDVVTGAQQDGIDWILLIKQQAYPLTNHKRKYKPLKIKKLSTNVDIDLDLDEFLTLYQQETGNKSLIN------DSLTLGDKADEFKRWDENSSAGSSQEGDIDDVVAGSTNNQK-VIYVPNMATRSKKANKREKWVYEDAARNSSNMILHNLSNAPIITVDALRDETLEIISITSLAQKEEWLRK----VFGSGNNSTPRSFATSIYNNLSKEAHKGNRWAILYCHKTGKSSVIDLQR", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . :.: : * :**:.:.:*: *. ** : .:* : : . *:. .. ** *:*.::: :.: :. :: *:..:: : *: :*:*:: .* * *.:: *: :: *: : .:: :.::. : .* .: .* .: * ::: . . . ... . : . .. . :: : . .* * : . :: * :: . .. . .. : . *.:..:: : .* *: . . : :: :. .: . * * :* .* :* .: *. : .*:: . . : .: . : :... *: ** *. .: . : *::.* . .. :** *:. . . . : . : . ** :** : **:**** *:*.:* **. **:*:* :. : ** **: *:*: :***: :*:* . ::: *. . . . : . *:.: : .. : . .. :.: .. .. : :.: :::. :. . ::****:**: ** *.. * .: . *****:* :.*::**.:*:*******:***:*. ::********. . .. *. :**::**:.*: . .. **:*:*:::****:*** : *. ** : **. : :.* : .:: *::*** :** * ** * :* . .*: : ::*:* .. : : : * . . : :. : . : ::.:*::**.:: :* : :. .: :.* :: * ** :**::: * ::* :::*:* . :.*:: : ***:: ::. * : ** : *: :* :.: * : :**: :*.::: . .: : : : : : : . : .* : ::: : .*: . .: * .:. *:. * : : * . . **::: : .::* * *** :: * . .. *..:: :.: . . : : . . :. : . **. .* . :: *. : : : : .: : :.:: :: . :* :.: : . : . . . * ... . : : . . : . .:* : .: : :: : ::.*: ::. : . . . . * : : . . **. . :: ", "identical_positions": 209, "similar_positions": 484, "identity": "11.64%" }, { "cls_id": "homologset.agr.MGI:1353428", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q925T0-1", "uniprot_id": "DJC12_RAT", "id": "Q925T0-1", "name": "DnaJ homolog subfamily C member 12", "aln": "---MDAILNYRPEGSEDYYTLLGCDELSSVEQILAEFKVRALECHPDKHPENSKAVETFQKLQKAKEILSNAESRARYDHWRRSQMSMSFEQWEALADSVKTSMHWAVRSKKDLMLEGSEQTYTNTAQNKERSEQRETKQGDPDSTPEKMMQKESESPEKGISPQNPDSPGLSDWNCGHLHFRWSGDTPSELLRKFRNYEI", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9R022-1", "uniprot_id": "DJC12_MOUSE", "id": "Q9R022-1", "name": "DnaJ homolog subfamily C member 12", "aln": "---MDAILNYRPEGSEDYYALLGCDELSSVEQILAEFKIRALECHPDKHPENSKAVETFQKLQKAKEILCNAESRARYDHWRRSQMSMPFEQWEALADSVKTSMHWAVRSKKDLMLEGSGQTFTSSVPNKERSEQRETKKGDPDSNPEKMKQKEPKFPEEGISPQNPDSPGLSDLNCGHLRFRWSGDAPSELLRKFRNYEI", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9UKB3-1", "uniprot_id": "DJC12_HUMAN", "id": "Q9UKB3-1", "name": "DnaJ homolog subfamily C member 12", "aln": "---MDAILNYRSEDTEDYYTLLGCDELSSVEQILAEFKVRALECHPDKHPENPKAVETFQKLQKAKEILTNEESRARYDHWRRSQMSMPFQQWEALNDSVKTSMHWVVRGKKDLMLEESDKTHTTKMENEECNEQRERKKEELASTAEKTEQKEPKPLEKSVSPQNSDSSGFADVNGWHLRFRWSKDAPSELLRKFRNYEI", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9TVP3-1", "uniprot_id": "JDP_DROME", "id": "Q9TVP3-1", "name": "J domain-containing protein", "aln": "MSAVDAIINYKRSPNEDFYGLLHCDENSSPEQIQAEYKVLALQYHPDKNSGDKEAEAKFQQLKEAKETLCDPEKRAIYDKWRNSGISMSYKQWLGMKEHVGQVRRYTIAEKVD---KESMHWVTPKTKDRMLPETGGAAAQGPGTGAGCSSGGLTAASPN--PAHRRASEGGAALYYGSRKGEWGGEN-TDVANKFRNYEI", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :***:**: . .**:* ** *** ** *** **:*: **: ****:. : :* .**:*::*** * : *.** **:**.* :**.::** .: : * ::.: * * : * : * . :. * : . . : ..:. * * : : .*. : ::: .*******", "identical_positions": 63, "similar_positions": 54, "identity": "31.34%" }, { "cls_id": "homologset.agr.MGI:1353429", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P62072-1", "uniprot_id": "TIM10_HUMAN", "id": "P62072-1", "name": "Mitochondrial import inner membrane translocase subunit Tim10", "aln": "----------MDPLRAQQ--LAAELEVEMMADMYNRMTSACHRKCVPPH-YKEAELSKGESVCLDRCVSKYLDIHERMGKKLTELSMQDEELMKRVQQSSGPA-------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P62073-1", "uniprot_id": "TIM10_MOUSE", "id": "P62073-1", "name": "Mitochondrial import inner membrane translocase subunit Tim10", "aln": "----------MDPLRAQQ--LAAELEVEMMADMYNRMTSACHRKCVPPH-YKEAELSKGESVCLDRCVSKYLDIHERMGKKLTELSMQDEELMKRVQQSSGPA-------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P62074-1", "uniprot_id": "TIM10_RAT", "id": "P62074-1", "name": "Mitochondrial import inner membrane translocase subunit Tim10", "aln": "----------MDPLRAQQ--LAAELEVEMMADMYNRMTSACHRKCVPPH-YKEAELSKGESVCLDRCVSKYLDIHERMGKKLTELSMQDEELMKRVQQSSGPA-------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q6DI06-1", "uniprot_id": "TIM10_DANRE", "id": "Q6DI06-1", "name": "Mitochondrial import inner membrane translocase subunit Tim10", "aln": "----------MDPMKAQQ--LAAELEVEMMADMYNRMTNACHRKCVPPH-YKEAELSKGEAVCLDRCVAKYLDLHERLGRKLTELSVQDEEVMRKAAAGTG---------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9W2D6-1", "uniprot_id": "TIM10_DROME", "id": "Q9W2D6-1", "name": "Mitochondrial import inner membrane translocase subunit Tim10", "aln": "-MALPQIS--TADQAKLQ--LMQEMEIEMMSDLYNRMTNACHKKCIPPR-YSESELGKGEMVCIDRCVAKYLDIHEKIGKKLTAMSMQDEELMKKMSS------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P87108-1", "uniprot_id": "TIM10_YEAST", "id": "P87108-1", "name": "Mitochondrial import inner membrane translocase subunit TIM10", "aln": "-MSFLGFGGGQPQLSSQQKIQAAEAELDLVTDMFNKLVNNCYKKCINTS-YSEGELNKNESSCLDRCVAKYFETNVQVGENMQKMG-QSFNAAGKF--------------", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P32830-1", "uniprot_id": "TIM12_YEAST", "id": "P32830-1", "name": "Mitochondrial import inner membrane translocase subunit TIM12", "aln": "MSFFLNSLRGNQEVSQEK-LDVAGVQFDAMCSTFNNILSTCLEKCIPHEGFGEPDLTKGEQCCIDRCVAKMHYSNRLIGGFVQTRGFGPENQLRHYSRFVAKEIADDSKK", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : :.: : . :*.: . * .**: : * :* *.* *:****:* : :* : . : : ", "identical_positions": 15, "similar_positions": 23, "identity": "13.64%" }, { "cls_id": "homologset.agr.MGI:1353431", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9QXV0-1", "uniprot_id": "PCS1N_MOUSE", "id": "Q9QXV0-1", "name": "ProSAAS", "aln": "MAGSPLLCGPRAGGVGILVLLLLGLLRLPPTLSARPVKEPRSLSAASAPLVETSTPLRLRRAVPRGEAAGAVQELARALAHLLEAERQERARAEAQEAEDQQARVLAQLLRAWGSPRASDPPLAPDDDPDAPAAQLARALLRARLDPAALAAQLVPAPA--AAPRPRPPVYDDGPTGPDVEDAGDETPDVDPELLRYLLGRILTGSSEPEAAPAPRRLRRSVDQDLGPEVPPENVLGALLRVKRLENPSPQAPARRLLPP", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9QXU9-1", "uniprot_id": "PCS1N_RAT", "id": "Q9QXU9-1", "name": "ProSAAS", "aln": "MAGSPLLCGPRAGGVGLLVLLLLGLLRLPPTLSARPVKEPRSLSAASAPLAETSTPLRLRRAVPRGEAAGAVQELARALAHLLEAERQERARAEAQEAEDQQARVLAQLLRAWGSPRASDPPLAPDDDPDAPAAQLARALLRARLDPAALAAQLVPAPAPAAALRPRPPVYDDGPTGPDVEDAADETPDVDPELLRYLLGRILTGSSEPEAAPAPRRLRRAVDQDLGPEVPPENVLGALLRVKRLENSSPQAPARRLLPP", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9UHG2-1", "uniprot_id": "PCS1N_HUMAN", "id": "Q9UHG2-1", "name": "ProSAAS", "aln": "MAGSPLLWGPRAGGVGLLVLLLLGLFRPPPALCARPVKEPRGLSAASPPLAETGAPRRFRRSVPRGEAAGAVQELARALAHLLEAERQERARAEAQEAEDQQARVLAQLLRVWGAPRNSDPALGLDDDPDAPAAQLARALLRARLDPAALAAQLVPAPVPAAALRPRPPVYDDGPAGPDAEEAGDETPDVDPELLRYLLGRILAGSADSEGVAAPRRLRRAADHDVGSELPPEGVLGALLRVKRLETPAPQVPARRLLPP", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "******* ********:********:* **:*.********.*****.**.**.:* *:**:*************************************************.**:** ***.*. *********************************. ** ***********:***.*:*.*******************:**::.*...*******:.*:*:*.*:***.************..:**.********", "identical_positions": 214, "similar_positions": 38, "identity": "82.31%" }, { "cls_id": "homologset.agr.MGI:1353432", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P62076-1", "uniprot_id": "TIM13_RAT", "id": "P62076-1", "name": "Mitochondrial import inner membrane translocase subunit Tim13", "aln": "------MDSGFGSDFG-GTGGGKLDPG----AIMEQVKVQIAVANAQELLQRMTDKCFRKCIGKPGGSLDNSEQKCIAMCMDRYMDAWNTVSRAYNSRLQRERANM--------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P62075-1", "uniprot_id": "TIM13_MOUSE", "id": "P62075-1", "name": "Mitochondrial import inner membrane translocase subunit Tim13", "aln": "------MDSGFGSDFG-GTGGGKLDPG----AIMEQVKVQIAVANAQELLQRMTDKCFRKCIGKPGGSLDNSEQKCIAMCMDRYMDAWNTVSRAYNSRLQRERANM--------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9Y5L4-1", "uniprot_id": "TIM13_HUMAN", "id": "Q9Y5L4-1", "name": "Mitochondrial import inner membrane translocase subunit Tim13", "aln": "------MEGGFGSDFG-GSGSGKLDPG----LIMEQVKVQIAVANAQELLQRMTDKCFRKCIGKPGGSLDNSEQKCIAMCMDRYMDAWNTVSRAYNSRLQRERANM--------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6DGJ3-1", "uniprot_id": "TIM13_DANRE", "id": "Q6DGJ3-1", "name": "Mitochondrial import inner membrane translocase subunit Tim13", "aln": "------MEG-FGSDFSSGSSSGKMDTG----TIMEQVKVQIAVANAQELLQRMTDKCFKKCIGKPGSTLDNSEQKCIAMCMDRYMDAWNTVSRAYNSRLQRERAHI--------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VTN3-1", "uniprot_id": "TIM13_DROME", "id": "Q9VTN3-1", "name": "Mitochondrial import inner membrane translocase subunit Tim13", "aln": "------------------MAAANMEKG----ELMNQVKQQIALANAQEMLSKMTEKCFKKCIQKPGKSLDSTEQRCISQCMDRFMDAWNLVSRTYGNRLQREQYRTMESLEMTS", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q0E8V7-1", "uniprot_id": "Q0E8V7_DROME", "id": "Q0E8V7-1", "name": "Mitochondrial import inner membrane translocase subunit", "aln": "------------------MAMANVDKG----ELMDQVKQQIAVANAQELLTQMTEKCFKKCVNKPGTSLDSSEQKCISMCMDRFMDSWNLISRVYGQRIQREQSKF--------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P53299-1", "uniprot_id": "TIM13_YEAST", "id": "P53299-1", "name": "Mitochondrial import inner membrane translocase subunit TIM13", "aln": "MGLSSIFGGGAPSQQKEAATTAKTTPNPIAKELKNQIAQELAVANATELVNKISENCFEKCLTSP---YATRNDACIDQCLAKYMRSWNVISKAYISRIQNASASGEI------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .: . : :*: ::*:*** *:: :::::**.**: .* . :: ** *: ::* :** :*:.* .*:*. ", "identical_positions": 21, "similar_positions": 32, "identity": "18.42%" }, { "cls_id": "homologset.agr.MGI:1353433", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9WVA2-1", "uniprot_id": "TIM8A_MOUSE", "id": "Q9WVA2-1", "name": "Mitochondrial import inner membrane translocase subunit Tim8 A", "aln": "MESSTSSSGSALGAVDP-QLQHFIEVETQKQRFQQLVHQMTELCWEKCMDKPG-PKLDSRAEACFVNCVERFIDTSQFILNRLEQTQKSKPVFSESLSD", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9WVA1-1", "uniprot_id": "TIM8A_RAT", "id": "Q9WVA1-1", "name": "Mitochondrial import inner membrane translocase subunit Tim8 A", "aln": "MESSSSSSGSALAAVDP-QLQHFIEVETQKQRFQQLVHQMTELCWEKCMDKPG-PKLDSRAEACFVNCVERFIDTSQFILNRLEQTQKSKPVFSESLSD", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O60220-1", "uniprot_id": "TIM8A_HUMAN", "id": "O60220-1", "name": "Mitochondrial import inner membrane translocase subunit Tim8 A", "aln": "MDSSSSSSAAGLGAVDP-QLQHFIEVETQKQRFQQLVHQMTELCWEKCMDKPG-PKLDSRAEACFVNCVERFIDTSQFILNRLEQTQKSKPVFSESLSD", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6DEM5-1", "uniprot_id": "TIM8A_DANRE", "id": "Q6DEM5-1", "name": "Mitochondrial import inner membrane translocase subunit Tim8 A", "aln": "MDTQG-------VATDP-QLQQFIEIESQKQRFQQLVHQMTEVCWEKCMDKPG-PKLDSRTEVCFVNCVERFIDTSQFILNRLEQTQRSRGAFSETMTD", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P57744-1", "uniprot_id": "TIM8_YEAST", "id": "P57744-1", "name": "Mitochondrial import inner membrane translocase subunit TIM8", "aln": "MSSLSTSDLASLDDTSKKEIATFLEGENSKQKVQMSIHQFTNICFKKCVESVNDSNLSSQEEQCLSNCVNRFLDTNIRIVNGLQNTR------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*.: .. :: *:* *..**:.* :**:*::*::**::. . .:*.*: * *: ***:**:**. *:* *::*: ", "identical_positions": 28, "similar_positions": 33, "identity": "28.28%" }, { "cls_id": "homologset.agr.MGI:1353434", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P10867-1", "uniprot_id": "GGLO_RAT", "id": "P10867-1", "name": "L-gulonolactone oxidase", "aln": "--MVHGYKGVQFQNWAKTYGCSPEVYYQPTSVEEVREVLALAREQKKKVKVVGGGHSPSDIACTDGFMIHMGKMNRVLQVDKE----KKQITVEAGILLADLHPQLDEHGLAMSNLGAVSDVTVAGVIGSGTHNTGIKHGILATQVVALTLMTADGEVLECSESRNADVFQAARVHLGCLGIILTVTLQCVPQFHLQETSFPSTLKEVLDNLDSHLKRSEYFRFLWFPHTENVSIIYQDHTNKAPSSASNWFWDYAIGFYLLEFLLWTSTYLPC-LVGWINRFFFWMLFNCKKESSN------LSHKIFTYECRFKQHVQDWAIPREKTKEALLELK---AMLEAHPKVVAHYPVEVRFT------------RGDDILLSPCFQ-------------------------RDSCYMNIIMYRPYGKDVPRLDYWLAYETIMKKFGGRPHWAKAHN-----------------------CTQKDFEEMYPTFHKFCDIREKLDPTGMFLNSYLEKVFY----------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P58710-1", "uniprot_id": "GGLO_MOUSE", "id": "P58710-1", "name": "L-gulonolactone oxidase", "aln": "--MVHGYKGVQFQNWAKTYGCSPEMYYQPTSVGEVREVLALARQQNKKVKVVGGGHSPSDIACTDGFMIHMGKMNRVLQVDKE----KKQVTVEAGILLTDLHPQLDKHGLALSNLGAVSDVTVGGVIGSGTHNTGIKHGILATQVVALTLMKADGTVLECSESSNADVFQAARVHLGCLGVILTVTLQCVPQFHLLETSFPSTLKEVLDNLDSHLKKSEYFRFLWFPHSENVSIIYQDHTNKEPSSASNWFWDYAIGFYLLEFLLWTSTYLPR-LVGWINRFFFWLLFNCKKESSN------LSHKIFSYECRFKQHVQDWAIPREKTKEALLELK---AMLEAHPKVVAHYPVEVRFT------------RGDDILLSPCFQ-------------------------RDSCYMNIIMYRPYGKDVPRLDYWLAYETIMKKFGGRPHWAKAHN-----------------------CTRKDFEKMYPAFHKFCDIREKLDPTGMFLNSYLEKVFY----------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P54783-1", "uniprot_id": "ALO_YEAST", "id": "P54783-1", "name": "D-arabinono-1,4-lactone oxidase", "aln": "MSTIPFRKNYVFKNWAGIYSAKPERYFQPSSIDEVVELVKSARLAEKSLVTVGSGHSPSNMCVTDEWLVNLDRLDKVQKFVEYPELHYADVTVDAGMRLYQLNEFLGAKGYSIQNLGSISEQSVAGIISTGSHGSSPYHGLISSQYVNLTIVNGKGELKFLDAENDPEVFKAALLSVGKIGIIVSATIRVVPGFNIKSTQEVITFENLLKQWDTLWTSSEFIRVWWYPYTRKCVLWRGNKTTDAQNGPAKSWWGTKLGRFFYETLLWISTKIYAPLTPFVEKFVFNRQYGKLEKSSTGDVNVTDSISGFNMDCLFSQFVDEWGCPMDNGLEVLRSLDHSIAQAAINKEFYVHVPMEVRCSNTTLPSEPLDTSKRTNTSPGPVYGNVCRPFLDNTPSHCRFAPLENVTNSQLTLYINATIYRPFGCNTPIHKWFTLFENTMMVAGGKPHWAKNFLGSTTLAAGPVKKDTDYDDFEMRGMALKVEEWYGEDLKKFRKIRKEQDPDNVFLANKQWAIINGIIDPSELSD", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : *. *:*** *...** *:**:*: ** *:: ** :*.: .**.*****::. ** :::::.::::* :. : ::**:**: * :*: *. :* ::.***::*: :*.*:*.:*:*.:. **::::* * **::...* : . . :.:**:** : :* :*:*::.*:: ** *:: .*. *::::*.: *: . **::*. *:*::.: : ::*.. ...:: :*. :* :: * *** ** : *. ::::*.* :. ::**. * . *. :* *.*.*::*. * :: *.* .*. * : :. .* *:*** : : : .* : : : *:* :***:* :.* .:: :*. * **:***** . : * * ::** .**:: ** .:** . :: ", "identical_positions": 130, "similar_positions": 175, "identity": "24.71%" }, { "cls_id": "homologset.agr.MGI:1353435", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q60584-1", "uniprot_id": "FBXW2_MOUSE", "id": "Q60584-1", "name": "F-box/WD repeat-containing protein 2", "aln": "MERKDFETWLDNISVTFLSLTDLQKNETLDHLISLSGAVQLRHLSNNLETLLKRDFLKLLPLELSFYLLKWLDPQTLLTCCLVSKQWNKVISACTEVWQTACKNLGWQIDDSVQDSLHWKKVYLKAILRMKQLEDHEAFETSSLIGHSARVYALYYKDGLLCTGSDDLSAKLWDVSTGQCVYGIQTHTCAAVKFDEQKLVTGSFDNTVACWEWSSGARTQHFRGHTGAVFSVDYSDELDILVSGSADFAVKVWALSAGTCLNTLTGHTEWVTKVVLQKCKVKSLLHSPGDYILLSADKYEIKIWPIGREINCKCLKTLSVSEDRSICLQPRLHFDGKYIVCSSALGLYQWDFASYDILRVIKTPEVANLALLGFGDVFALLFDNHYLYIMDLRTESLISRWPLPEYRKSKRGSSFLAGERPG--------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "B2RZ17-1", "uniprot_id": "FBXW2_RAT", "id": "B2RZ17-1", "name": "F-box/WD repeat-containing protein 2", "aln": "MERKDFETWLDNISVTFLSLTDLQKNETLDHLISLSGAVQLRHLSNNLETLLKRDFLKLLPLELSFYLLKWLDPQTLLTCCLVSKQWNKVISACTEVWQTACKNLGWQIDDSVQDALHWKKVYLKAILRMKQLEDHEAFETSSLIGHSARVYALYYKDGLLCTGSDDLSAKLWDVSTGQCVYGIQTHTCAAVKFDEQKLVTGSFDNTVACWEWSSGARTQHFRGHTGAVFSVDYSDELDILVSGSADFAVKVWALSAGTCLNTLTGHTEWVTKVVLQQCKVKSLLHSPGDYILLSADKYEIKIWPIGREINCKCLKTLSVSEDRSICLQPRLHFDGKYIVCSSALGLYQWDFASYDILRVIKTPEVANLALLGFGDVFALLFDNHYLYIMDLRTESLISRWPLPEYRKSKRGSSFLAGEASWLNGLDGHNDTGLVFATSMPDHSIHLVLWKEHG", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9UKT8-1", "uniprot_id": "FBXW2_HUMAN", "id": "Q9UKT8-1", "name": "F-box/WD repeat-containing protein 2", "aln": "MERKDFETWLDNISVTFLSLTDLQKNETLDHLISLSGAVQLRHLSNNLETLLKRDFLKLLPLELSFYLLKWLDPQTLLTCCLVSKQWNKVISACTEVWQTACKNLGWQIDDSVQDALHWKKVYLKAILRMKQLEDHEAFETSSLIGHSARVYALYYKDGLLCTGSDDLSAKLWDVSTGQCVYGIQTHTCAAVKFDEQKLVTGSFDNTVACWEWSSGARTQHFRGHTGAVFSVDYNDELDILVSGSADFTVKVWALSAGTCLNTLTGHTEWVTKVVLQKCKVKSLLHSPGDYILLSADKYEIKIWPIGREINCKCLKTLSVSEDRSICLQPRLHFDGKYIVCSSALGLYQWDFASYDILRVIKTPEIANLALLGFGDIFALLFDNRYLYIMDLRTESLISRWPLPEYRKSKRGSSFLAGEASWLNGLDGHNDTGLVFATSMPDHSIHLVLWKEHG", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*******************************************************************************************************************:**********************************************************************************************************************.*************:****************************:***************************************************************************************:**********:*******:********************************** . ", "identical_positions": 412, "similar_positions": 8, "identity": "90.75%" }, { "cls_id": "homologset.agr.MGI:1353436", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9WV98-1", "uniprot_id": "TIM9_MOUSE", "id": "Q9WV98-1", "name": "Mitochondrial import inner membrane translocase subunit Tim9", "aln": "-------MAAQIPESDQIKQFKEFLGTYNKLTETCFLDCVKDFTTREVKPEEVTCSEHCLQKYLKMTQRISVRFQEYHIQQNE---ALAAKAGLLGQPR", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9WV97-1", "uniprot_id": "TIM9_RAT", "id": "Q9WV97-1", "name": "Mitochondrial import inner membrane translocase subunit Tim9", "aln": "-------MAAQIPESDQIKQFKEFLGTYNKLTETCFLDCVKDFTTREVKPEEVTCSEHCLQKYLKMTQRISMRFQEYHIQQNE---ALAAKAGLLGQPR", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9Y5J7-1", "uniprot_id": "TIM9_HUMAN", "id": "Q9Y5J7-1", "name": "Mitochondrial import inner membrane translocase subunit Tim9", "aln": "-------MAAQIPESDQIKQFKEFLGTYNKLTETCFLDCVKDFTTREVKPEETTCSEHCLQKYLKMTQRISMRFQEYHIQQNE---ALAAKAGLLGQPR", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9W762-1", "uniprot_id": "TIM9_DANRE", "id": "Q9W762-1", "name": "Mitochondrial import inner membrane translocase subunit Tim9", "aln": "-------MAAQVTESDQIKQFKEFLGTYNKLTENCFMDCVKDFTTREVKPEETTCSESCLQKYLKMTQRISMRFQEYHIQQNE---RWPQKPDY-----", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VYD7-1", "uniprot_id": "TIM9_DROME", "id": "Q9VYD7-1", "name": "Mitochondrial import inner membrane translocase subunit Tim9", "aln": "MAKTPENIAIDQLDKDQIKTFSDFLMSYNKLSETCFTDCIRDFTTRDVKDSEEKCSLNCMEKYLKMNQRVSQRFQEFQVIAHENALAMAQKTGKL----", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "O74700-1", "uniprot_id": "TIM9_YEAST", "id": "O74700-1", "name": "Mitochondrial import inner membrane translocase subunit TIM9", "aln": "MDALNSKEQQEFQKVVEQKQMKDFMRLYSNLVERCFTDCVNDFTTSKLTNKEQTCIMKCSEKFLKHSERVGQRFQEQNA-------ALGQGLGR-----", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . : * :.:*: *.:* * ** **:.**** .:. .* .* * :*:** .:*:. **** : . ", "identical_positions": 24, "similar_positions": 24, "identity": "24.24%" }, { "cls_id": "homologset.agr.MGI:1353437", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "F1QG70-1", "uniprot_id": "F1QG70_DANRE", "id": "F1QG70-1", "name": "stearoyl-CoA 9-desaturase", "aln": "---------------------------------------MPDSDVK-----APVLQP---------------------------QLEAMEDEFDPLYKEK--PGPKPPMKIVWRNVILMSLLHIAAVYGLFLIPS--AHPLTLLWAFACFVYGGLGITAGVHRLWSHRSYKATLPLRIFLAIGNSMAFQNDIYEWSRDHRVHHKYSETDADPHNSNRGFFFSHVGWLLVRKHPEVIERGRKLELTDLKADKVVMFQRRFYKLSVVLMCFVVPTVVPCYMWGESLWIAYFIPTLLRYALGLNSTWLVNSAAHMWGNRPYDGNIGPRENRFVTFSAIGEGYHNYHHTFPYDYSTSEYG-WKLNLTTIFVDTMCFLGLASNRKRVSKELILARVKRTGDGSYRSG------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8M2B301-1", "uniprot_id": "A0A8M2B301_DANRE", "id": "A0A8M2B301-1", "name": "stearoyl-CoA 9-desaturase", "aln": "---------------------------------------MVASQARRQYTSTEAMAD---------------------------VTTTTEDVFDDSYVEK--PGPSPPVQIVWRNVILMTLLHLGALYGMTILPF--VSSLTLIWTGVCFMVSALGITAGAHRLWSHRSYRASLPLRIFLAVANSMAFQNDIYEWARDHRVHHKFSETDADPHNARRGFFFAHIGWLLVRKHPEVIDKGRKLTFEDLKADSVVMFQRRHYKLSVVVMCFLIPTLVPWFFWEESLWTAYLVPCLLRYAVVLNATWLVNSAAHMWGMRPYDHNINPRENKFVAFSAIGEGFHNYHHTFPHDYATSEFG-SRLNVTKAFIDLMCFLGLANDCRRVTHETILARVQRTGDGSHKSG------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q99PL7-1", "uniprot_id": "SCD3_MOUSE", "id": "Q99PL7-1", "name": "Acyl-CoA desaturase 3", "aln": "-----------------------------------MPGHLLQEEMTPSYTTTTTITAPPSGSLQNGREKVKTVPLYLEED---IRPEMKEDIYDPTYQDE--EGPPPKLEYVWRNIILMALLHVGALYGITLVPS--CKLYTCLFAFVYYVISIEGIGAGVHRLWSHRTYKARLPLRIFLIIANTMAFQNDVYEWARDHRAHHKFSETHADPHNSRRGFFFSHVGWLLVRKHPAVKEKGGKLDMSDLKAEKLVMFQRRYYKPGILLMCFILPTLVPWYCWGETFLNSFYVATLLRYAVVLNATWLVNSAAHLYGYRPYDKNIDPRQNALVSLGSMGEGFHNYHHAFPYDYSASEYR-WHINFTTFFIDCMAALGLAYDRKRVSKATVLARIKRTGDGSHKSG------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Z4YNJ9-1", "uniprot_id": "Z4YNJ9_RAT", "id": "Z4YNJ9-1", "name": "", "aln": "-----------------------------------MPGHLLQEEMTPSYTTTSTITEPPSGVMQKGKEKLKTLPLYLEED---IRPEMREDIHDPSYQDE--EGPPPKLEYVWRNIILMALLHVGALYGITLIPS--SKVYTLLWAFIYYAISIEGIGAGVHRLWSHRTYKARLPLRIFLIIANTMAFQNDVYEWARDHRAHHKFTETHADPHNSRRGFFFSHVGWLLVRKHPAVKEKGGKLDMSDLKAEKLVMFQRRYYKPGILLLCFILPTLVPWYFWGETFLHSFYVATLLRYAVVLNVTWLVNSAAHLYGYRPYDKNIDPRENALVSLGTLGEGFHNYHHAFPYDYSASEYP-WHINFTTFFIDCMAFLGLAYDRKRVSKATVLARIKRTGDGSHKSG------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O00767-1", "uniprot_id": "SCD_HUMAN", "id": "O00767-1", "name": "Stearoyl-CoA desaturase", "aln": "-----------------------------------MPAHLLQDDISSSYTTTTTITAPPSRVLQNGGDKLETMPLYLEDD---IRPDIKDDIYDPTYKDK--EGPSPKVEYVWRNIILMSLLHLGALYGITLIPT--CKFYTWLWGVFYYFVSALGITAGAHRLWSHRSYKARLPLRLFLIIANTMAFQNDVYEWARDHRAHHKFSETHADPHNSRRGFFFSHVGWLLVRKHPAVKEKGSTLDLSDLEAEKLVMFQRRYYKPGLLMMCFILPTLVPWYFWGETFQNSVFVATFLRYAVVLNATWLVNSAAHLFGYRPYDKNISPRENILVSLGAVGEGFHNYHHSFPYDYSASEYR-WHINFTTFFIDCMAALGLAYDRKKVSKAAILARIKRTGDGNYKSG------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VA94-1", "uniprot_id": "Q9VA94_DROME", "id": "Q9VA94-1", "name": "Fatty acid desaturase domain-containing protein", "aln": "----MGHLSTSERVCSKTPAIATDSSPPLVARRSKFPNGDAQQQVRRGEDSSPELPPRGKLQLPPKREELPRSVVPKEIANHVPKDAIDLEEYTRTFVGDRVLGWQFQAPLKWDKVIQISLLHIVAGICLLTYPLRELNPYTTIWSFFVGGVAGFGVTAGAHRFWTHKSYKANTVLRSILMVCYCVAGQNTLYDWVRDHRVHHKYSETDADPHNANRGFFFSHVGWLMMLKHPEVLRRGRQIDMSDILADPVVRFHQKYFIPLKTFFCFILPTVIPVYCWGETWTLAFIQQCLFRYVSSLNFTWSVNSAAHLWGSRPYDKRIMPSENIYVSLLAMGEGWHNYHHVFPWDYKAAELGNYTVNFTTMVLDAFHKLGWAWNMKQPSKELVRRTLEKYGDGTHASQLGGPEE-----------FKDGVLAGATMVGHVHYAEVPDPELEYDAESSSTESAKLDENENEGERMKKSKKAAN----------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VTD4-1", "uniprot_id": "Q9VTD4_DROME", "id": "Q9VTD4-1", "name": "", "aln": "-------------------------------------------MPRNTKDTTGVLYESD-------------------------VETVDGGLSTELSNRKTTDGS--KLELVWVNIVLFVILHISSLYGVWLLFTS-ATWTTVVLFWPTVVVTILGVSGGAHRLWAHRTFKANTPLKLIFLFLNTLAFQDAVYYWARDHRVHHKYTETDADPYNSQRGWFFAHIGWLCCRKHPEVVEKGKQIDLSDLEADPLIMFQKKYYLLLMPIICFVLPTVLPMYLWGESLNVSWHVMALLRWCLSLNLIWTVNSSAHMHGMRPYDKNICPVDQGFLIFFRVGEGYHNYHHVFPWDYKSAELGKYSQDVTTKFIEFMAYLGWAYDLKSVSLDLVKQRVQRSGDGS------------------------------------------HPVWGWGDKDQLKEDVGVTTITHQRNEK------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VG68-1", "uniprot_id": "Q9VG68_DROME", "id": "Q9VG68-1", "name": "", "aln": "-----------------------------------MAPYSRIYHQDKSSRETGVLFEDD-------------------------AQTVDGDLTTDRFQLKRAEKR--RLPLVWRNIILFALVHLAALYGLHSIFTR-AKLATTLFAAGLYIIGMLGVTAGAHRLWAHRTYKAKWPLRLLLVIFNTIAFQDAVYHWARDHRVHHKYSETDADPHNATRGFFFSHVGWLLCKKHPDIKEKGRGLDLSDLRADPILMFQRKHYYILMPLACFVLPTVIPMVYWNETLASSWFVATMFRWCFQLNMTWLVNSAAHKFGNRPYDKTMNPTQNAFVSAFTFGEGWHNYHHAFPWDYKTAEWGCYSLNITTAFIDLFAKIGWAYDLKTVAPDVIQRRVLRTGDGS------------------------------------------HELWGWGDKDLTAEDARNVLLVDKSR--------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VFX5-1", "uniprot_id": "Q9VFX5_DROME", "id": "Q9VFX5-1", "name": "Fatty acid desaturase domain-containing protein", "aln": "------------------------MSPNIIGSTFILAETAIADGNNNKMAATPAASAAP-------------------------SAATPSQKVAKKAEAKTPENKPYELEIVWRNVGLFVILHSMALYGLYLVFAE-SAYWELLPVYATMFLGGLGITAGVHRLWSHKAYKAKLPLRIFLMLCQSLAFQNSIWEWTRDHRVHHKFTDTHADPHNSRRGFFFAHMGWLMCKKHPDVTSKGKQISMEDIEQDPVVMFQKKMYFVVMPICCFALPMIFPYYVMGSSLRVCFFTCSMLRFCLSLHFTWLVNSAAHFYGMKPYDVNVSAMNNKLVSTLTIGEGWHNYHHVFPWDYKAAELGTYSFNWTTAFIDVMAKIGQAYDLKFVSQEMVYKRVLRTGDGSHIAALLDANN-----------NSA--IPTSELVAHLDHEKEEHAIWGWDDKDISEEDRKGANVVNKESECKLD---------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VA92-1", "uniprot_id": "Q9VA92_DROME", "id": "Q9VA92-1", "name": "Fatty acid desaturase domain-containing protein", "aln": "MCLSSPIPGQKQATSVGHCNGSCSLDRNGNRSAAIVPNGGELKHRGHATDATSHTLVKDDDNLGYKEENAVYKE----------QQLLQQQDQTLKEAEQVEEEEEYHPQIRWPDLGAQAFLHIGALYGLYQLFY--ANFYTFLWVVVTVWVSGIGITAGAHRLWSHKSYTASLPLRILLAFAFSIAGQRDAYTWALDHRIHHKFSETDADPHNAKRGFFFAHVGWLFLTPHPKVVAKRKVIDMSDLEADAVCMFQRKYYIPLFALCSIILPVAVPWYFWNEDLWMSFWINFNMRFTWTLNVAFFVNSVAHMYGNKPYDKNLMSTEAPIVSLLAMGEGWHNYHHVFPWDYKTGEFGNYSLNITTGFIDFCAWLGLAKGRKSVSPDMVLRRAKKCGDGTRFLD--------------------------------DDHAHKDPVWGFGDKDIPREDIVELAKMQN----------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VA93-1", "uniprot_id": "Q9VA93_DROME", "id": "Q9VA93-1", "name": "Fatty acid desaturase domain-containing protein", "aln": "-----------------------------------------------------------------------------------------METTKVKEPDQSGDSIHKKRDAIWPLVLFYIHLNILGVYGIYVLLTS-ASWATILFTALLTLLGTLGVTVGVHRLWAHRTFTASKPLKVFLMFCQTTAGQGSIYSVVQAHRLHHAKFQQDEDPYYSKHSFMYAQVRGGLLKYSPQQEELLKDVDMSDLESDPVVMFQKRFYVLLYIFLNVLLSVNTPFQYFGDSLATSMFVGFWLRSLIVINLGNLVHSSHFIWS---IHKGFKPTDSNSIFLITKSY-WPQYHYLLPRDYQSGEYGNYASGIGSSMIRVFAALDWAKDLKTIGSVAVRQGLTKAVETG------------------------------------------RPIVECIEEQVELEENALPANHFLNREKFM----------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P21147-1", "uniprot_id": "ACO1_YEAST", "id": "P21147-1", "name": "Acyl-CoA desaturase 1", "aln": "MPTSGTTIELIDDQFPKDDSASSGIVDEVDLTEANILATGLNKKAPRIVNGFGSLMGSKEMVSVEFDKKGNEKKSNLDRLLEKDNQEKEEAKTKIHISEQPWTLNNWHQHLNWLNMVLVCGMPMIGWYFALSGKVP-LHLNVFLFSVFYYAVGGVSITAGYHRLWSHRSYSAHWPLRLFYAIFGCASVEGSAKWWGHSHRIHHRYTDTLRDPYDARRGLWYSHMGWMLLKPNPKYKAR---ADITDMTDDWTIRFQHRHYILLMLLTAFVIPTLICGYFFNDYMGGLIYAG-FIRVFVIQQATFCINSLAHYIGTQPFDDRRTPRDNWITAIVTFGEGYHNFHHEFPTDYRN-AIKWYQYDPTKVIIYLTSLVGLAYDLKKFSQNAIEEALIQQEQKKINKKKAKINWGPVLTDLPMWDKQTFLAKSKENKGLVIISGIVHDVSGYISEHPGGETLIKTALGKDATKAFSGGVYRHSNAAQNVLADMRVAVIKESKNSAIRMASKRGEIYETGKFF", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . * : : . : .: * **:*:*::: * *: : . : : ** ** : **: : :. :::: * : *: : *::: : . . :. . :* : ::* . . . . : . : ::*: :* ** . . .: :. * . : : : : ", "identical_positions": 24, "similar_positions": 64, "identity": "4.65%" }, { "cls_id": "homologset.agr.MGI:1353438", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O08911-1", "uniprot_id": "MK12_MOUSE", "id": "O08911-1", "name": "Mitogen-activated protein kinase 12", "aln": "MSSPPPARKGFYRQEVTKTAWEVRAVYQDLQPVGSGAYGAVCSAVDSRTGNKVAIKKLYRPFQSELFAKRAYRELRLLKHMRHENVIGLLDVFTPDES-LDDFTDFYLVMPFMGTDLGKLMKHETLSEDRIQFLVYQMLKGLKYIHAAGVIHRDLKPGNLAVNEDCELKILDFGLARQADSEMTGYVVTRWYRAPEVILNWMRYTQTVDIWSVGCIMAEMITGKILFKGNDHLDQLKEIMKITGTPPPEFVQKLQSAEAKNYMEGLPELEKKDFASVLTNASPQAVNLLERMLVLDAEQRVTAAEALTHPYFESLRDTEDEPKA--QKYDDSFDDVDRTLEEWKRVTYKEVLSFK------------------------PPRQLGARVPKETAL----------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q63538-1", "uniprot_id": "MK12_RAT", "id": "Q63538-1", "name": "Mitogen-activated protein kinase 12", "aln": "MSSPPPARKGFYRQEVTKTAWEVRAVYQDLQPVGSGAYGAVCSAVDSRTGNKVAIKKLYRPFQSELFAKRAYRELRLLKHMRHENVIGLLDVFTPDET-LDDFTDFYLVMPFMGTDLGKLMKHETLSEDRIQFLVYQMLKGLKYIHAAGVIHRDLKPGNLAVNEDCELKILDFGLARQADSEMTGYVVTRWYRAPEVILNWMRYTQTVDIWSVGCIMAEMITGKILFKGNDHLDQLKEIMKVTGTPPPEFVQKLQSAEAKNYMEGLPELEKKDFASVLTNASPQAVNLLEKMLVLDAEQRVTAAEALAHPYFESLRDTEDEPKA--QKYDDSFDDVDRTLEEWKRVTYKEVLSFK------------------------PPRQLGARVPKETAL----------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P53778-1", "uniprot_id": "MK12_HUMAN", "id": "P53778-1", "name": "Mitogen-activated protein kinase 12", "aln": "MSSPPPARSGFYRQEVTKTAWEVRAVYRDLQPVGSGAYGAVCSAVDGRTGAKVAIKKLYRPFQSELFAKRAYRELRLLKHMRHENVIGLLDVFTPDET-LDDFTDFYLVMPFMGTDLGKLMKHEKLGEDRIQFLVYQMLKGLRYIHAAGIIHRDLKPGNLAVNEDCELKILDFGLARQADSEMTGYVVTRWYRAPEVILNWMRYTQTVDIWSVGCIMAEMITGKTLFKGSDHLDQLKEIMKVTGTPPAEFVQRLQSDEAKNYMKGLPELEKKDFASILTNASPLAVNLLEKMLVLDAEQRVTAGEALAHPYFESLHDTEDEPQV--QKYDDSFDDVDRTLDEWKRVTYKEVLSFK------------------------PPRQLGARVSKETPL----------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "O42376-1", "uniprot_id": "MK12_DANRE", "id": "O42376-1", "name": "Mitogen-activated protein kinase 12", "aln": "MTAR--SRPGYFRQEINKTIWEVPDRYKDLKQVGTGAYGTVCYALDRRTGAKVAIKKLHRPFQSDLFAKRAYRELRLLKHMKHDNVIGLVDVFTADLS-LDRFHDFYLVMPFMGTDLGKLMKMERLSEERVQYLVYQMLKGLKYIHAAGIIHRDLKPGNLAINEECELKILDFGLARQTDSEMTGYVVTRWYRAPEVILSWMHYTQTVDIWSVGCIMAEMLLGKPLFKGHDHLDQLMEIMKVTGTPSKEFTAKLQSEDARNYVTKLPRFRKKDLRILLPNVNPQAIKVLDGMLLLDPESRITAAEALAFPFFSEFREPEEETEA--PPYDHSLDEADQSLEQWKRLTFTEILTFQ------------------------PAPAVAE--SKETAL----------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P32485-1", "uniprot_id": "HOG1_YEAST", "id": "P32485-1", "name": "Mitogen-activated protein kinase HOG1", "aln": "MTTN----EEFIRTQIFGTVFEITNRYNDLNPVGMGAFGLVCSATDTLTSQPVAIKKIMKPFSTAVLAKRTYRELKLLKHLRHENLICLQDIF------LSPLEDIYFVTELQGTDLHRLLQTRPLEKQFVQYFLYQILRGLKYVHSAGVIHRDLKPSNILINENCDLKICDFGLARIQDPQMTGYVSTRYYRAPEIMLTWQKYDVEVDIWSAGCIFAEMIEGKPLFPGKDHVHQFSIITDLLGSPPKDVINTICSENTLKFVTSLPHRDPIPFSERFKTVEPDAVDLLEKMLVFDPKKRITAADALAHPYSAPYHDPTDEPVAD-AKFDWHFNDADLPVDTWRVMMYSEILDFHKIGGSDGQIDISATFDDQVAAATAAAAQAQAQAQAQVQLNMAAHSHNGAGTTGNDHSDIAGGNKVSDHVAANDTITDYGNQAIQYANEFQQ", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P83100-1", "uniprot_id": "MK14C_DROME", "id": "P83100-1", "name": "Putative mitogen-activated protein kinase 14C", "aln": "-------MPEFVRVAINESLWEFPDIYEFVRFLGGGSFGQVAKVRLRGTENYFAMKRLMRPFEREEDAKGTYREIRLLKHMNHRNVISLLNVFHPPAHNMMEFQQVYLVTHLMDADLHRYSRSKRMSDQEIRIILYQILRGLKYIHSAGVVHRDLKPCNIAVNGNSEVRILDFGLSRMCADKMTDHVGTMWYLAPEIIFLRGQYTKAIDVWSVGCILAELITDRVLFRGENYVSQIRCLINIMGTPTREFITGISMERSRNYLEGYPLRQRCDFHHLFMGYDVQAIDLMEKMLEMVPEKRITAAEAMLHPYLRDLIEPHHHAEDTAPVYDQNFENMVLPVKCWKELVSHEIRNFR---------------------------------PDQLDLHF--------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : * : : :*. *. :. :* *::* *. . * .*:*:: :**. ** :***::****:.* *:* * ::* : : :.*:* : .:** : : . : .: :: ::**:*:**:*:*:**::****** *: :* :.:::* ****:* :**.:* * :* ***::: :* :*:**.***:**:: .: ** * ::: *: : .: *:*. :. : : ::: * : : . *:.::: ** : .:.*:**.:*: .*: :. ... :* ::: .:. *: : *: *: : * ", "identical_positions": 90, "similar_positions": 127, "identity": "20.18%" }, { "cls_id": "homologset.agr.MGI:1353448", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q63185-1", "uniprot_id": "E2AK1_RAT", "id": "Q63185-1", "name": "Eukaryotic translation initiation factor 2-alpha kinase 1", "aln": "MLGGGSVDGERDTDDDAAGAVAAPPAIDFPAEV----------------------SDPKYDESDVPAELQVFKEPLQQP---TFPFLVANQLLLVSLLEHLSHVHEPNPLHSKQVFKLLCQTFIKMGLLSSFTCSDEFSSLRLHHNRAITHLMRSAKERVRQDPCQDNSY-MQKIRSREIALEAQTSRYLNEFEELAILGKGGYGRVYKVRNKLDGQHYAIKKILIKSATKTDCMKVLREVKVLAGLQHPNIVGYHTAWIEHVHVLQP-QDRVPIQLPSLEVLSEHEGDRNQGGVKDNESSSS-IIFAELT--PEKENPLA-ESDVKNENNNLVSYRANLVIRSSSESE-----SSIELQEDGLNESPLRPVVKHQLPLGHSS--DVEGNFTSTDESSEDNLNLLGQTEARYHLMLHIQMQLCELSLWDWIAERNNRSRE--CVDEAACPYVMASVATKIFQELVEGVFYIHNMGIVHRDLKPRNIFLHGPDQQVKIGDFGLACADIIQKSADWTNRNGKG----TPTHTSRVGTCLYASPEQLEGSEYDAKSDMYSLGVILLELFQPFGTEMERATVLTGVRTGRIPESLSKRCPVQAKYIQLLTGRNAAQRPSALQLLQSELFQTTGNVNLTLQMKIMEQEKEIEELKKQLSLLSQDKGLKR--------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9Z2R9-1", "uniprot_id": "E2AK1_MOUSE", "id": "Q9Z2R9-1", "name": "Eukaryotic translation initiation factor 2-alpha kinase 1", "aln": "MLGGSSVDGERDTDDDAAGAVAAPPAIDFPAEV----------------------SDPKYDESDVPAELQVLKEPLQQP---TFPFLVANQLLLVSLLEHLSHVHEPNPLHSKQVFKLLCQTFIKMGLLSSFTCSDEFSSLRLHHNRAITHLMRSAKERVRQDPCQDNSY-MQKIRSREIAFEAQTSRYLNEFEELAILGKGGYGRVYKVRNKLDGQHYAIKKILIKSATKTDCMKVLREVKVLAGLQHPNIVGYHTAWIEHVHVVQP-QDRVPIQLPSLEVLSEQEGDRDQGGVKDNESSSS-IVFAELT--PEKEKPFG-ESEVKNENNNLVSYTANLVVRNSSESE-----SSIELQEDGLTDLSVRPVVRHQLPLGHSS--ELEGNFTSTDESSEGNLNLLGQTEVRYHLMLHIQMQLCELSLWDWITERNKRSRE--YVDEAACPYVMASVATKIFQELVEGVFYIHNMGIVHRDLKPRNIFLHGPDQQVKIGDFGLACADIIQN-ADWTNRNGKG----TRTHTSRVGTCLYASPEQLEGSQYDAKSDMYSLGVILLELFQPFGTEMERATVLTGVRTGRIPESLSKRCPVQAKYIQLLTGRNVSQRPSALQLLQSELFQTTGNVNLTLQMKIIEQEKEIEELKKQLSLLSQDRGLKR--------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9BQI3-1", "uniprot_id": "E2AK1_HUMAN", "id": "Q9BQI3-1", "name": "Eukaryotic translation initiation factor 2-alpha kinase 1", "aln": "MQGGNSGVRKREEEGDGAGAVAAPPAIDFPAEG----------------------PDPEYDESDVPAEIQVLKEPLQQP---TFPFAVANQLLLVSLLEHLSHVHEPNPLRSRQVFKLLCQTFIKMGLLSSFTCSDEFSSLRLHHNRAITHLMRSAKERVRQDPCEDISR-IQKIRSREVALEAQTSRYLNEFEELAILGKGGYGRVYKVRNKLDGQYYAIKKILIKGATKTVCMKVLREVKVLAGLQHPNIVGYHTAWIEHVHVIQPRADRAAIELPSLEVLSDQEEDREQCGVKNDESSSSSIIFAEPT--PEKEKRFG-ESDTENQNNKSVKYTTNLVIRESGELE-----STLELQENGLAGLSASSIVEQQLPLRRNS--HLEESFTSTEESSEENVNFLGQTEAQYHLMLHIQMQLCELSLWDWIVERNKRGRE--YVDESACPYVMANVATKIFQELVEGVFYIHNMGIVHRDLKPRNIFLHGPDQQVKIGDFGLACTDILQKNTDWTNRNGKR----TPTHTSRVGTCLYASPEQLEGSEYDAKSDMYSLGVVLLELFQPFGTEMERAEVLTGLRTGQLPESLRKRCPVQAKYIQHLTRRNSSQRPSAIQLLQSELFQNSGNVNLTLQMKIIEQEKEIAELKKQLNLLSQDKGVRDDGKDGGVG", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1NBY7-1", "uniprot_id": "A0A8M1NBY7_DANRE", "id": "A0A8M1NBY7-1", "name": "Eukaryotic translation initiation factor 2-alpha kinase 1", "aln": "MFHRKETLMVVESSSNVSSVVSNVNSRSLHLQRGLSTQERESNIRGKMFSLTDTEDDVQFDTSDSDTNCEVLLAGKQYPSIQEFASAIPNQLLLGSLLEHLCFVYESDPTRSRMLFKVIGQRLAAMNLLSPLAISDEFSTVRLQHNRAFTELLHATSSSLFPQEHKYLSTEGQSKRTKDGLFQAQTSRYLSEFEEIATLGKGSYGKVFRVTNKLDGQEYAVKKILIKKVTRDDCMKVLREVKVLSSLQHPNIVGYHTAWMEHVQPAVT-VDSNSLVSQTFPALDRPSEPNGCTPEHTNSSNGSFIVFEHSERAEVKENQVALESISVNPSTSKVDMAQSVCPKNVRKPQNFVPCVFLGKPRSTLNKCPAANWDSSTLSEDDLSQNRLELNKHSYIDMDTPEWSEKQENKVQFHLMLYIQMQLCERSLKDWIQERNSRTTEGLLMSGDPCDSVDCEQALKILKKILEGVEYIHSCGIMHRDLKPRNIFLLGNECHVKIGDFGLACQNIIMDEHEKLPSSSQAGVNPDATHTSGVGTFVYAAPEQLEGSRYDSKSDMYSIGVIAFELFQPFGTEMERVHTLGELRQGKIPNTLSTNWPILAKYIKLLTSSDPSMRPSAPQLLQSDLFSTNDMVIHSLKRKIDEQEEEIVQLRRRISELQISQNSIHSPEKT---", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* . : ..: :..*: : .: : * ::* ** :: :*: * * *. :.***** ******..*:*.:* :*: :**:: * : *.***.:: *****::**:****:*.*::::.. : : : * *. *::: ::*******.****:* ****.**:*::* ****** **:****** .*: ***********:.*************:***: . * .: :: .*. . . : :.*..* *:* . **: .. ** * ... *. .: :. : : : .. * . *. * :* . * : . : . :.:.::****:******* ** *** ***.* * :. .* * .. * **:::::*** ***. **:*********** * : :********** :*: . : ..: **** *** :**:*******.**:******:**: :************. .* :* *::*::* .. *: ****: ** : : **** *****:**.... * :*: ** ***:** :*::::. *. .:. ", "identical_positions": 256, "similar_positions": 177, "identity": "38.1%" }, { "cls_id": "homologset.agr.MGI:1353449", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q63184-1", "uniprot_id": "E2AK2_RAT", "id": "Q63184-1", "name": "Interferon-induced, double-stranded RNA-activated protein kinase", "aln": "MASDT-PGFYVDKLNKYSQIHKVKIIYKEISVTGPPHDRRFTFQVIIEEREFPEGEGRSKQEAKNNAAKLAVEILDNENKVDS----HTDASEQGLIEGNYIGLVNSFAQKENLPVNFELCDPDSQLPHRFICKCKIGQTTYGTGFGANKKEAKQLAAKNAYQKLSEKSPSKTG------------------FVTSLSSDFSSSSS--ITSNSASQSASG-RDFEDIFMNGLRE-KRKSGVKVPS----DDVLRNKYTLDDRFSKDFEDIEEIGSGGFGQVFKAKHRIDGKTYAIKRITYNTKKAKREVQALAELNHANIVQYRVCWEGEDYDYDPEN------------STNGDTSRYKTRCLFIQMEFCDKGTLQQWLEKRNRSQEDKALVLELFEQIVTGVDYIHSKGLIHRDLKPGNIFLVDEKHIKIGDFGLATALENDGNPRTKYTGTPQYMSPEQKSSLVEYGKEVDIFALGLILAELLHICKTDSEKIEFFQLLRNGIFSDDIFDNKEKSLLQKLLSSKPRERPNTSEILKTLAEWKNISEKKKRNTC", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q03963-1", "uniprot_id": "E2AK2_MOUSE", "id": "Q03963-1", "name": "Interferon-induced, double-stranded RNA-activated protein kinase", "aln": "MASDT-PGFYMDKLNKYRQMHGVAITYKELSTSGPPHDRRFTFQVLIDEKEFPEAKGRSKQEARNAAAKLAVDILDNENKVDC----HTSASEQGLFVGNYIGLVNSFAQKKKLSVNYEQCEPNSELPQRFICKCKIGQTMYGTGSGVTKQEAKQLAAKEAYQKLLKSPPKTAGTSSS--------------VVTSTFSGFSSSSS--MTSNGVSQSAPGSFSSENVFTNGLGENKRKSGVKVSP----DDVQRNKYTLDARFNSDFEDIEEIGLGGFGQVFKAKHRIDGKRYAIKRVKYNTEKAEHEVQALAELNHVNIVQYHSCWEG--VDYDPEH------------SMS-DTSRYKTRCLFIQMEFCDKGTLEQWMRNRNQSKVDKALILDLYEQIVTGVEYIHSKGLIHRDLKPGNIFLVDERHIKIGDFGLATALENDGKSRTRRTGTLQYMSPEQ-LFLKHYGKEVDIFALGLILAELLHTCFTESEKIKFFESLRKGDFSNDIFDNKEKSLLKKLLSEKPKDRPETSEILKTLAEWRNISEKKKRNTC", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P19525-1", "uniprot_id": "E2AK2_HUMAN", "id": "P19525-1", "name": "Interferon-induced, double-stranded RNA-activated protein kinase", "aln": "MAGDLSAGFFMEELNTYRQKQGVVLKYQELPNSGPPHDRRFTFQVIIDGREFPEGEGRSKKEAKNAAAKLAVEILNKEKKAVSPLLLTTTNSSEGLSMGNYIGLINRIAQKKRLTVNYEQCASGVHGPEGFHYKCKMGQKEYSIGTGSTKQEAKQLAAKLAYLQILSEETSVKSDYLSSGSFATTCESQSNSLVTSTLASESSSEGDFSADTSEINSNSDSLNSSSLLMNGLRNNQRKAKRSLAPRFDLPDMKETKYTVDKRFGMDFKEIELIGSGGFGQVFKAKHRIDGKTYVIKRVKYNNEKAEREVKALAKLDHVNIVHYNGCWDG--FDYDPETSDDSLESSDYDPENSKNSSRSKTKCLFIQMEFCDKGTLEQWIEKRRGEKLDKVLALELFEQITKGVDYIHSKKLIHRDLKPSNIFLVDTKQVKIGDFGLVTSLKNDGK-RTRSKGTLRYMSPEQ-ISSQDYGKEVDLYALGLILAELLHVCDTAFETSKFFTDLRDGIIS-DIFDKKEKTLLQKLLSKKPEDRPNTSEILRTLTVWKKSPEKNERHTC", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "**.* .**::::**.* * : * : *:*:. :************:*: :****.:****:**:* ******:**::*:*. . * *.:** ******:* :***:.*.**:* * .. . *. * ***:**. *. * * .*:******** ** :: .. .. . .*** :. ***.. :... :* .. . ..:: *** : :**: .:.. *: ..***:* **. **::** ** **************** *.***:.**.:**::**:***:*:*.***:*. **:* ***** . . ::** **:**************:**:.:*. .: **.* *:*:***..**:***** ********.****** :::*******.*:*:***: **: .** :****** .******::*********** * * *. :** **.* :* ****:***:**:****.**.:**:*****:**: *:: .**::*:**", "identical_positions": 282, "similar_positions": 146, "identity": "50.72%" }, { "cls_id": "homologset.agr.MGI:1353450", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P46367-1", "uniprot_id": "ALDH4_YEAST", "id": "P46367-1", "name": "Potassium-activated aldehyde dehydrogenase, mitochondrial", "aln": "MFSRSTLCLKTSASSIGRLQLRYFSHLPMTVPIKLPNGLEYEQPTGLFINNKFVPSKQNKTFEVINPSTEEEICHIYEGREDDVEEAVQAADRAFSNG-SWNGIDPIDRGKALYRLAELIEQDKDVIASIETLDNGKAISSS-RGDVDLVINYLKSSAGFADKIDGRMIDTGRTHFSYTKRQPLGVCGQIIPWNFPLLMWAWKIAPALVTGNTVVLKTAESTPLSALYVSKYIPQAGIPPGVINIVSGFGKIVGEAITNHPKIKKVAFTGSTATGRHIYQSAAAG-LKKVTLELGGKSPNIVFADAELKKAVQNIILGIYYNSGEVCCAGSRVYVEESIYDKFIEEFKAASES-IKVGDPFDESTFQGAQTSQMQLNKILKYVDIGKNEGATLITGGERLGSKGYFIKPTVFGDVKEDMRIVKEEIFGPVVTVTKFKSADEVINMANDSEYGLAAGIHTSNINTALKVADRVNAGTVWINTYNDFHHAVPFGGFNASGLGREMSVDALQNYLQVKAVRAKLDE---", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P40047-1", "uniprot_id": "ALDH5_YEAST", "id": "P40047-1", "name": "Aldehyde dehydrogenase 5, mitochondrial", "aln": "MLSR-TRAAAPNSRIFTRSLLRLYSQAPLRVPITLPNGFTYEQPTGLFINGEFVASKQKKTFDVINPSNEEKITTVYKAMEDDVDEAVAAAKKAFET--KWSIVEPEVRAKALFNLADLVEKHQETLAAIESMDNGKSLFCA-RGDVALVSKYLRSCGGWADKIYGNVIDTGKNHFTYSIKEPLGVCGQIIPWNFPLLMWSWKIGPALATGNTVVLKPAETTPLSALFASQLCQEAGIPAGVVNILPGSGRVVGERLSAHPDVKKIAFTGSTATGRHIMKVAADT-VKKVTLELGGKSPNIVFADADLDKAVKNIAFGIFYNSGEVCCAGSRIYIQDTVYEEVLQKLKDYTES-LKVGDPFDEEVFQGAQTSDKQLHKILDYVDVAKSEGARLVTGGARHGSKGYFVKPTVFADVKEDMRIVKEEVFGPIVTVSKFSTVDEVIAMANDSQYGLAAGIHTNDINKAVDVSKRVKAGTVWINTYNNFHQNVPFGGFGQSGIGREMGEAALSNYTQTKSVRIAIDKPIR", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P54115-1", "uniprot_id": "ALDH6_YEAST", "id": "P54115-1", "name": "Magnesium-activated aldehyde dehydrogenase, cytosolic", "aln": "-------------------MTKLHFDTAEPVKITLPNGLTYEQPTGLFINNKFMKAQDGKTYPVEDPSTENTVCEVSSATTEDVEYAIECADRAFHDT-EWATQDPRERGRLLSKLADELESQIDLVSSIEALDNGKTLALA-RGDVTIAINCLRDAAAYADKVNGRTINTGDGYMNFTTLEPIGVCGQIIPWNFPIMMLAWKIAPALAMGNVCILKPAAVTPLNALYFASLCKKVGIPAGVVNIVPGPGRTVGAALTNDPRIRKLAFTGSTEVGKSVAVDSSESNLKKITLELGGKSAHLVFDDANIKKTLPNLVNGIFKNAGQICSSGSRIYVQEGIYDELLAAFKAYLETEIKVGNPFDKANFQGAITNRQQFDTIMNYIDIGKKEGAKILTGGEKVGDKGYFIRPTVFYDVNEDMRIVKEEIFGPVVTVAKFKTLEEGVEMANSSEFGLGSGIETESLSTGLKVAKMLKAGTVWINTYNDFDSRVPFGGVKQSGYGREMGEEVYHAYTEVKAVRIKL-----", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P24549-1", "uniprot_id": "AL1A1_MOUSE", "id": "P24549-1", "name": "Aldehyde dehydrogenase 1A1", "aln": "----------------------MSSPAQPAVPAPLAD--LKIQHTKIFINNEWHNSVSGKKFPVLNPATEEVICHVEEGDKADVDKAVKAARQAFQIGSPWRTMDASERGRLLNKLADLMERDRLLLATMEALNGGKVFANAYLSDLGGCIKALKYCAGWADKIHGQTIPSDGDIFTYTRREPIGVCGQIIPWNFPMLMFIWKIGPALSCGNTVVVKPAEQTPLTALHLASLIKEAGFPPGVVNIVPGYGPTAGAAISSHMDVDKVAFTGSTQVGKLIKEAAGKSNLKRVTLELGGKSPCIVFADADLDIAVEFAHHGVFYHQGQCCVAASRIFVEESVYDEFVKRSVERAKK-YVLGNPLTPGINQGPQIDKEQHDKILDLIESGKKEGAKLECGGGRWGNKGFFVQPTVFSNVTDEMRIAKEEIFGPVQQIMKFKSVDDVIKRANNTTYGLAAGLFTKDLDKAITVSSALQAGVVWVNCYMMLSAQCPFGGFKMSGNGRELGEHGLYEYTELKTVAMKISQKNS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P51647-1", "uniprot_id": "AL1A1_RAT", "id": "P51647-1", "name": "Aldehyde dehydrogenase 1A1", "aln": "----------------------MSSPAQPAVPAPLAN--LKIQHTKIFINNEWHDSVSGKKFPVLNPATEEVICHVEEGDKADVDKAVKAARQAFQIGSPWRTMDASERGRLLNKLADLMERDRLLLATIEAINGGKVFANAYLSDLGGSIKALKYCAGWADKIHGQTIPSDGDIFTFTRREPIGVCGQIIPWNFPLLMFIWKIGPALSCGNTVVVKPAEQTPLTALHMASLIKEAGFPPGVVNIVPGYGPTAGAAISSHMDVDKVAFTGSTQVGKLIKEAAGKSNLKRVTLELGGKSPCIVFADADLDIAVEFAHHGVFYHQGQCCVAASRIFVEESVYDEFVRKSVERAKK-YVLGNPLTQGINQGPQIDKEQHDKILDLIESGKKEGAKLECGGGRWGNKGFFVQPTVFSNVTDEMRIAKEEIFGPVQQIMKFKSIDDVIKRANNTTYGLAAGVFTKDLDRAITVSSALQAGVVWVNCYMILSAQCPFGGFKMSGNGRELGEHGLYEYTELKTVAMKISQKNS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P00352-1", "uniprot_id": "AL1A1_HUMAN", "id": "P00352-1", "name": "Aldehyde dehydrogenase 1A1", "aln": "----------------------MSSSGTPDLPVLLTD--LKIQYTKIFINNEWHDSVSGKKFPVFNPATEEELCQVEEGDKEDVDKAVKAARQAFQIGSPWRTMDASERGRLLYKLADLIERDRLLLATMESMNGGKLYSNAYLNDLAGCIKTLRYCAGWADKIQGRTIPIDGNFFTYTRHEPIGVCGQIIPWNFPLVMLIWKIGPALSCGNTVVVKPAEQTPLTALHVASLIKEAGFPPGVVNIVPGYGPTAGAAISSHMDIDKVAFTGSTEVGKLIKEAAGKSNLKRVTLELGGKSPCIVLADADLDNAVEFAHHGVFYHQGQCCIAASRIFVEESIYDEFVRRSVERAKK-YILGNPLTPGVTQGPQIDKEQYDKILDLIESGKKEGAKLECGGGPWGNKGYFVQPTVFSNVTDEMRIAKEEIFGPVQQIMKFKSLDDVIKRANNTFYGLSAGVFTKDIDKAITISSALQAGTVWVNCYGVVSAQCPFGGFKMSGNGRELGEYGFHEYTEVKTVTVKISQKNS", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : *.: * * :***.:: : . *.: * :*:.*: : : .. **: *: .* :** * :. *.: * .**: :* . ::::*:::.** : .*: : *: ...:***: *. * . :.:: :*:************::* ***.*** **. ::*.* ***.**. :. :.*:*.**:**:.* * .* :: . : *:****** .*: : :. :*::********. :*: **::. :: *:: : *: * :.**::::: :*::.: :. :*:*: **. . * ..*:. :: .*.*** : ** *.**:*::**** :*.::***.***:***: : **.: :: : **.: :**.:*: *..:. .: ::. ::**.**:* * . ****. ** ***:. * : *:* : ", "identical_positions": 152, "similar_positions": 172, "identity": "28.9%" }, { "cls_id": "homologset.agr.MGI:1353451", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P47739-1", "uniprot_id": "AL3A1_MOUSE", "id": "P47739-1", "name": "Aldehyde dehydrogenase, dimeric NADP-preferring", "aln": "------------------------------------------------------------------MSNISSIVNRARDAFNSG-KTRPLQFRVEQLEALQRMINENLKGISKALASNLRKNEWTSYYEEVAHVLDEIDFTIKGLSDWAEDEPVAKT-RQTQEDDLYIHSEPLGVVLVIGAWNYPFNLTIQPMVGAIAAGNAVVLKPSEVSDHMADLLSTLIPQY-MDKDLYPVIKGGVPETTELLKE-KFDHIMYTGSTAVGKIVMAAAAKHLTPVTLELGGKSPCYVDK---DCDLDVACRRIAWGKFMNSGQTCVAPDYILCDPSIQNEIVEKLKKSLKDFYGEDAKQSHDYGRIINDRHFQRVINLIDSKK-------VAHGGTWDQPSRYIAPTILVDVDPQSPVMQEEIFGPVMPIVCVRSLDEAIK-FINQREKPLALYVFSNNDKVIKKMIAETSSGGVTANDVIVHITVPTLPFGGVGNSGMGAYHGKKSFETFSHRRSCLVRSLR--NEEANKARYPP-SPAKMPRH-------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P11883-1", "uniprot_id": "AL3A1_RAT", "id": "P11883-1", "name": "Aldehyde dehydrogenase, dimeric NADP-preferring", "aln": "------------------------------------------------------------------MSSISDTVKRAREAFNSG-KTRSLQFRIQQLEALQRMINENLKSISGALASDLGKNEWTSYYEEVAHVLEELDTTIKELPDWAEDEPVAKT-RQTQQDDLYIHSEPLGVVLVIGAWNYPFNLTIQPMVGAVAAGNAVILKPSEVSGHMADLLATLIPQY-MDQNLYLVVKGGVPETTELLKE-RFDHIMYTGSTAVGKIVMAAAAKHLTPVTLELGGKSPCYVDK---DCDLDVACRRIAWGKFMNSGQTCVAPDYILCDPSIQNQIVEKLKKSLKDFYGEDAKQSRDYGRIINDRHFQRVKGLIDNQK-------VAHGGTWDQSSRYIAPTILVDVDPQSPVMQEEIFGPVMPIVCVRSLEEAIQ-FINQREKPLALYVFSNNEKVIKKMIAETSSGGVTANDVIVHITVPTLPFGGVGNSGMGAYHGKKSFETFSHRRSCLVKSLL--NEEAHKARYPP-SPAKMPRH-------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P30838-1", "uniprot_id": "AL3A1_HUMAN", "id": "P30838-1", "name": "Aldehyde dehydrogenase, dimeric NADP-preferring", "aln": "------------------------------------------------------------------MSKISEAVKRARAAFSSG-RTRPLQFRIQQLEALQRLIQEQEQELVGALAADLHKNEWNAYYEEVVYVLEEIEYMIQKLPEWAADEPVEKT-PQTQQDELYIHSEPLGVVLVIGTWNYPFNLTIQPMVGAIAAGNSVVLKPSELSENMASLLATIIPQY-LDKDLYPVINGGVPETTELLKE-RFDHILYTGSTGVGKIIMTAAAKHLTPVTLELGGKSPCYVDK---NCDLDVACRRIAWGKFMNSGQTCVAPDYILCDPSIQNQIVEKLKKSLKEFYGEDAKKSRDYGRIISARHFQRVMGLIEGQK-------VAYGGTGDAATRYIAPTILTDVDPQSPVMQEEIFGPVLPIVCVRSLEEAIQ-FINQREKPLALYMFSSNDKVIKKMIAETSSGGVAANDVIVHITLHSLPFGGVGNSGMGSYHGKKSFETFSHRRSCLVRPLM--NDEGLKVRYPP-SPAKMTQH-------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0ACD6B720-1", "uniprot_id": "A0ACD6B720_DANRE", "id": "A0ACD6B720-1", "name": "Aldehyde dehydrogenase", "aln": "--------------------------------------------------------------------MEKQVVDGLREVFQSG-RSRPLQYRKQQLRALLRLITERHADIEQALKQDLNRSMHGTSLFELIGIENDIKVAEREMTEWAAPRPVKKN-LNSALDDVYVKPEPLGVVLIIGTWNYPWAMIFQPLVGAIAAGNAAVVKPSELSEHSSRLMKELLPLY-LDKEMYQVVTGGVPETQELLKQ-RFDHIFYTGSSTVGKLVMEAASRHLTPVTLELGGKSPCYIDK---NCDIAVACRRITWGKFANCGQTCIAPDYILCEPSIQDRIVEEIQKTLLEFYQTDPKSSPDYCRIINTRHFDRVLALMNECT-------IALGGENDRSQCYIAPTVLKDVLPHFKIMQEEIFGPLLPIVTVNGLSEAIN-FINAREKPLALYVFSSDKTVIKRMLKETTSGGVTVNDVLMHYTVDTLPFGGVGNSGMGRYHGKHTFDQLSHHRACLIKSFA--MESLNDARYPPLTTARLRKAKFFMGHRMCSCNGMCVWAVIATVLAIGLLVGLLVVLI------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A0C4DHC8-1", "uniprot_id": "A0A0C4DHC8_DROME", "id": "A0A0C4DHC8-1", "name": "", "aln": "MFDNAIKPHPEANGAPINAAGDRPITTVINIEPEPETESPIGIFTSQPESQQQQPEQLQSESESDRMANFDDTLQRARLAFSSG-KTRNVSFRRKQLENLLRCYEEHENEIISALEADLRRPKQESLIVETEFMKNDIRHILFQLDEWVQSEKPPKS-FVNMMDDVQIYNDPFGVVLVIGAWNYPLQLLLVPVASAIAAGNCVVIKPSEIAANCAKFIADVIPKY-LDNDCYPVVCGGPSETAELLNQ-RFDYIFYTGSTRVGKIIHAAANKYLTPTTLELGGKSPCYIDK---SVDMRTAVKRILWGKLINCGQTCIAPDYILCSKEVQEKFIVEAKDVLKEWYGENIQSSPDLSRVINANNFQRLLGLMKSGR-------VAVGGNYDASERFIEPTILVDVKETDPIMEEEIFGPILPIFNVESAYDAIK-FINAREKPLVIYVFSNSNKLVKEFRRSTTSGGFSSNETIMHCGVDVLPFGGVGMSGMGRYHGKYGFETFTHKKSCLGKDLSPLGEKLSSARYPPYSDRKGSLLSFLLRKRRPLPN-LHLSHVLAIGLGVGLTVLTNYYLQGKLLSK", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q04458-1", "uniprot_id": "HFD1_YEAST", "id": "Q04458-1", "name": "Fatty aldehyde dehydrogenase HFD1", "aln": "--------------------------------------------MSNDGSKILNYTPVSKIDEIVEISRNFFFEKQLKLSHENNPRKKDLEFRQLQLKKLYYAVKDHEEELIDAMYKDFHRNKIESVLNETTKLMNDILHLIEILPKLIKPRRVSDSSPPFMFGKTIVEKISRGSVLIIAPFNFPLLLAFAPLAAALAAGNTIVLKPSELTPHTAVVMENLLTTAGFPDGLIQVVQGAIDETTRLLDCGKFDLIFYTGSPRVGSIVAEKAAKSLTPCVLELGGKSPTFITENFKASNIKIALKRIFFGAFGNSGQICVSPDYLLVHKSIYPKVIKECESVLNEFYPS-FDEQTDFTRMIHEPAYKKAVASINSTNGSKIVPSKISINSDTEDLCLVPPTIVYNIGWDDPLMKQENFAPVLPIIEYEDLDETINKIIEEHDTPLVQYIFSDSQTEINRILTRLRSGDCVVGDTVIHVGITDAPFGGIGTSGYGNYGGYYGFNTFSHERTIFKQPYWN--DFTLFMRYPPNSAQKEKLVRFAMERKPWFDRNGNNKWGLRQYFSLSAAVILISTIYAHCSS-", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . : .... :.: :.:* **. * :. : *: :: : : * : ::: : . . .. .. : . * **:*..:*:* : : *:..*:**** ::****:: : : .: ::. : . *: *. ** .**. :** *:****. **.:: * : *** .******** :: : :: * :** :* : *.** *::***:* .: ..: : :. * ::* ... * *:* :.: :. . : **:: :: :*::* *.*::**. .. ::*: :*: ::.**. *:**.... ::.: **. .:.::* : ****:* ** * * * *: ::*.:: : : : **** : : ", "identical_positions": 100, "similar_positions": 153, "identity": "17.24%" }, { "cls_id": "homologset.agr.MGI:1353452", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "E9QH31-1", "uniprot_id": "E9QH31_DANRE", "id": "E9QH31-1", "name": "Aldehyde dehydrogenase", "aln": "------------------------------------------------------------------MSREQKAVERARKAFFTG-RSKSLEYRISQLKNLQRFMQERQKEIAEALKKDLKRSEFGTSLYETLGVESEINLALKKLKEWAAPRPVNKS-LMTISDQVYIQPEPLGVVLIIGAWNYPWAVTVGPLVGAIAAGNAAVIKPSEVSAHTSKVMEEFLPLY-LDKELYPVVTGGVKETQELLKQ-RFDHIFYTGNGMVGKIIMEAAAKHLTPTTLELGGKSPCYIDK---DCDLTIACRRIAWGKYSNCGQTCIAPDYILCDPSIQDRVIEEIKKNIKEFYTENPQKCPDYGRIINQRHFKRLMSLMEGS-------SIAVSGEHNEAECYIAPTVLRDVKPDAKVMQEEIFGPLLPIVTVNSVDEAIK-FINQRDKPLALYIFSSDKKLIDRMIAETSSGGLMANDCLMHFSVSSLPFGGVGDSGMGRYHGKHGFDNLSHMRGVLLKQLK--MEAVNKMRYPPHTADKLGWARFFIVRHVDFGSLG---RMAMLALMVVFAAVIIQKYFTD------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0ACD6B720-1", "uniprot_id": "A0ACD6B720_DANRE", "id": "A0ACD6B720-1", "name": "Aldehyde dehydrogenase", "aln": "--------------------------------------------------------------------MEKQVVDGLREVFQSG-RSRPLQYRKQQLRALLRLITERHADIEQALKQDLNRSMHGTSLFELIGIENDIKVAEREMTEWAAPRPVKKN-LNSALDDVYVKPEPLGVVLIIGTWNYPWAMIFQPLVGAIAAGNAAVVKPSELSEHSSRLMKELLPLY-LDKEMYQVVTGGVPETQELLKQ-RFDHIFYTGSSTVGKLVMEAASRHLTPVTLELGGKSPCYIDK---NCDIAVACRRITWGKFANCGQTCIAPDYILCEPSIQDRIVEEIQKTLLEFYQTDPKSSPDYCRIINTRHFDRVLALMNEC-------TIALGGENDRSQCYIAPTVLKDVLPHFKIMQEEIFGPLLPIVTVNGLSEAIN-FINAREKPLALYVFSSDKTVIKRMLKETTSGGVTVNDVLMHYTVDTLPFGGVGNSGMGRYHGKHTFDQLSHHRACLIKSFA--MESLNDARYPPLTTARLRKAKFFMG-HRMCSCNG---MCVWAVIATVLAIGLLVGLLVVLI----", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P47740-1", "uniprot_id": "AL3A2_MOUSE", "id": "P47740-1", "name": "Aldehyde dehydrogenase family 3 member A2", "aln": "---------------------------------------------------------------------MERQVLRLRQAFRSG-RSRPLRFRLQQLEALRRMVQEREKEILAAIAADLSKSELNAYSHEVITILGEIDFMLGNLPELASARPAKKN-LLTMMDEAYVQPEPLGVVLIIGAWNYPFVLTMQPLVGAIAAGNAAIVKPSELSENTAKILAELLPQY-LDQDLYAIVNGGIPETTELLKQ-RFDHILYTGNTAVGKIVMEAAAKHLTPVTLELGGKSPCYIDR---DCDLDVACRRIAWGKYMNCGQTCIAPDYILCEASLQNQIVQKIKETVKDFYGENIKASPDYERIINLRHFKRLQSLLKGQ-------KIAFGGEMDEATRYLAPTILTDVDPNSKVMQEEIFGPILPIVSVKNVDEAIN-FINDREKPLALYVFSRNNKLIKRVIDETSSGGVTGNDVIMHFTVNSLPFGGVGASGMGAYHGKYSFDTFSHQRPCLLKGLK--GESVNKLRYPPNSESKVSWAKFFLLKQFNKGRLG---MLLFVCLVAVAAVIVKDQL---------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P30839-1", "uniprot_id": "AL3A2_RAT", "id": "P30839-1", "name": "Aldehyde dehydrogenase family 3 member A2", "aln": "---------------------------------------------------------------------MERQVQRLRQTFRSG-RSRPLRFRLQQLEALRRMVQEREKDILAAIAADLSKSELNAYSHEVITILGEIDFMLGNLPELASARPAKKN-LLTMMDEAYVQPEPLGVVLIIGAWNYPFVLTLQPLVGAIAAGNAAIVKPSELSENTAKILAELLPQY-LDQDLYMIVNGGVEETTELLRQ-RFDHILYTGNTAVGKIVMEAAAKHLTPVTLELGGKSPCYIDR---DCDLDVACRRITWGKYMNCGQTCIAPDYILCEASSQDQIVQKIKDTVKDFYGENVKASPDYERIINLRHFKRIKSLLEGQ-------KIAFGGETDEATRYIAPTILTDVDPNSKVMQEEIFGPILPIVSVKNVEEAIN-FINDREKPLALYIFSHNNKLIKRVIDETSSGGVTGNDVIMHFTVNSLPFGGVGASGMGAYHGKYSFDTFSHQRPCLLKGLK--GESVNKLRYPPNSESKVSWSKFFLLKQFNKGRLQ---LLLLVCLVAVAAVIVKDQL---------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P51648-1", "uniprot_id": "AL3A2_HUMAN", "id": "P51648-1", "name": "Aldehyde dehydrogenase family 3 member A2", "aln": "---------------------------------------------------------------------MELEVRRVRQAFLSG-RSRPLRFRLQQLEALRRMVQEREKDILTAIAADLCKSEFNVYSQEVITVLGEIDFMLENLPEWVTAKPVKKN-VLTMLDEAYIQPQPLGVVLIIGAWNYPFVLTIQPLIGAIAAGNAVIIKPSELSENTAKILAKLLPQY-LDQDLYIVINGGVEETTELLKQ-RFDHIFYTGNTAVGKIVMEAAAKHLTPVTLELGGKSPCYIDK---DCDLDIVCRRITWGKYMNCGQTCIAPDYILCEASLQNQIVWKIKETVKEFYGENIKESPDYERIINLRHFKRILSLLEGQ-------KIAFGGETDEATRYIAPTVLTDVDPKTKVMQEEIFGPILPIVPVKNVDEAIN-FINEREKPLALYVFSHNHKLIKRMIDETSSGGVTGNDVIMHFTLNSFPFGGVGSSGMGAYHGKHSFDTFSHQRPCLLKSLK--REGANKLRYPPNSQSKVDWGKFFLLKRFNKEKLG---LLLLTFLGIVAAVLVKAEYY--------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A0C4DHC8-1", "uniprot_id": "A0A0C4DHC8_DROME", "id": "A0A0C4DHC8-1", "name": "", "aln": "MFDNAIKPHPEANGAPINAAGDRPITTVINIEPEPETESPIGIFTSQPESQQQQPEQLQSESESDRMANFDDTLQRARLAFSSG-KTRNVSFRRKQLENLLRCYEEHENEIISALEADLRRPKQESLIVETEFMKNDIRHILFQLDEWVQSEKPPKS-FVNMMDDVQIYNDPFGVVLVIGAWNYPLQLLLVPVASAIAAGNCVVIKPSEIAANCAKFIADVIPKY-LDNDCYPVVCGGPSETAELLNQ-RFDYIFYTGSTRVGKIIHAAANKYLTPTTLELGGKSPCYIDK---SVDMRTAVKRILWGKLINCGQTCIAPDYILCSKEVQEKFIVEAKDVLKEWYGENIQSSPDLSRVINANNFQRLLGLMKSG-------RVAVGGNYDASERFIEPTILVDVKETDPIMEEEIFGPILPIFNVESAYDAIK-FINAREKPLVIYVFSNSNKLVKEFRRSTTSGGFSSNETIMHCGVDVLPFGGVGMSGMGRYHGKYGFETFTHKKSCLGKDLSPLGEKLSSARYPPYSDRKGSLLSFLLRKRRPLPNLH---LSHVLAIGLGVGLTVLTNYYLQGKLLSK", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q04458-1", "uniprot_id": "HFD1_YEAST", "id": "Q04458-1", "name": "Fatty aldehyde dehydrogenase HFD1", "aln": "--------------------------------------------MSNDGSKILNYTPVSKIDEIVEISRNFFFEKQLKLSHENNPRKKDLEFRQLQLKKLYYAVKDHEEELIDAMYKDFHRNKIESVLNETTKLMNDILHLIEILPKLIKPRRVSDSSPPFMFGKTIVEKISRGSVLIIAPFNFPLLLAFAPLAAALAAGNTIVLKPSELTPHTAVVMENLLTTAGFPDGLIQVVQGAIDETTRLLDCGKFDLIFYTGSPRVGSIVAEKAAKSLTPCVLELGGKSPTFITENFKASNIKIALKRIFFGAFGNSGQICVSPDYLLVHKSIYPKVIKECESVLNEFYP-SFDEQTDFTRMIHEPAYKKAVASINSTNGSKIVPSKISINSDTEDLCLVPPTIVYNIGWDDPLMKQENFAPVLPIIEYEDLDETINKIIEEHDTPLVQYIFSDSQTEINRILTRLRSGDCVVGDTVIHVGITDAPFGGIGTSGYGNYGGYYGFNTFSHERTIFKQPYWN--DFTLFMRYPPNSAQKEKLVRFAMERKPWFDRNGNNKWGLRQYFSLSAAVILISTIYAHCSS---", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . .. :.: : :* **. * ::. :: *: *: : * : .:* : : .. .. ... : . * **:*..:*:* : . *: .*:**** ::****:: : : .: ..:. : . :: *. ** .** :** *:***. **.:: * : *** .******** :* . :: . :** :* *.** *::***:* . :.: : :. : ::* . . .* *:*: :.: . :: .. : **:: :: :*::* *.*:***. :. ::*: :*: ::.**. *:** .:. :... **. .: ::* : ****:* ** * * * : *: ::* : : : : **** : : * : : : . : ", "identical_positions": 101, "similar_positions": 154, "identity": "17.35%" }, { "cls_id": "homologset.agr.MGI:1353455", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D4ADG4-1", "uniprot_id": "D4ADG4_RAT", "id": "D4ADG4-1", "name": "", "aln": "---MIRCLSDEVQAKLRSGLALSSLGQCVEELTLNSIDAEATCVAIRVNMETFQVQVIDNGLGMAGDDVEKVGNRYFTSKCHSVRDLENPTFYGFRGEALASIADMASAVEISSKKSTTLKTFVKMFQNGKALAA----------READLTRPSVGTTVTVYNLFYQFPVRR---KSMDPRLEFEKVRQRVEALSLMHPSISFSLRNDV-----------SGSMILQLPKTKDICSRFCQIYG-LGKSQKLREIHYKYKEFEFNGYISSEAHYNKNMQFLFVNRRLVLRTKLHKLIDFLLRKESIICRPKNGSASRQMNSSPRHRSASELHGIYVINVQCPFCEYDVCIEPAKTLIEFQNWDTVLICVQEGIKKFLKQEKLFVELSSEDIKEFNEDNGFSLIGTTLQTQS-THEKCDQSSFQEACNNILDSYEMFNLQSKAVKRIATLENRTTQNSGDSGAIRKKTEDS--YTYESDDLGHRKTVESALYNSD-SAYLGSRMSEEDIAKTSHAGENEKWKKSLLENRTSERPHETSPKMFSSPIQTHHPLEESEADLEIEMKSSTVNVMAANIPPNSEIQSQLEQLEDAPEVECQPLPFETTLLRAQGTLKKKER-KKELSSHGRVNVFSYGQVKLCSTGFITHVVQREPAKSPETEQLFKNYARPGPVSAQEAFGNRTHHASETPDSSSLTSTLSKESTQPPHKRFCRTNTGYGTENKPVATDDNLALFQGSRKESHTDCFLPDTT-SFPWCRNVSGGYKKKGKVGSF-KHVVRRKLSLRSQIGSLEKFKRQYGKVNNSLAAEEDNDTDFRTHLEPHNEPDVLLKDKSLSDMSDGGEITPSEHSDG---CQPLRPILYPET--LSKED--RLEQRPSLRESPITLAELLHGNRKPSEVKKSTEALASKLSRLK-DSEKEMQTMEMAGPVSERPDSDPSWKDNSQCARLDLNFCELYKNKLEKTESEVLPMPDSAPEDDSINKNSVLCSN-SVTDDREKPETSLLLPCSDSKIS-KDSDVLIRVSEQQSGSPDSASREVTRQVEDSAGSQCGICSQSHGFKARSCSDNEESSTHSMDWQQHFDVTLGRTVYINRMTGLSTFVAP-TDDIQTPCTKDLTTVAVDVLLGNGVQYRCHPFRSDLVLPFLPRAQEERTRRR-HNRDAVD--AAAVSEPLQSLFSEWSNPVFARYPEVAVDVSSGQAGSLAVKIHNVLYPYRFTKEMIHSVQVLQQVDNKFIACLMSSRTDGSGQAEILVGFVGGNLLVLVDQHAAHERVRLEQLITDSYEKQAPQSAGRKKLLSSTIIPPLAITVSEEQRRLLRSYHKHLEDLGLELLFPD--ASDSSILVGKVPLCFVEREANELRRGRSPVTKSIVEELIREQLELLQTTGG------------IQGTLPLTVQKVLASQACHGAIKFNDRLSLEESCRLIEALSLCQLPFQCAHGRPSMLPLADLDHLEQEKQV-KPNLTKLRKMAHAWHLFGKAEGCDTKQEPQQPVPPCEPP", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0A1Y7VMP7-1", "uniprot_id": "A0A1Y7VMP7_MOUSE", "id": "A0A1Y7VMP7-1", "name": "", "aln": "---MIRCLSDDVKTKLRSGLAISSLGQCVEELTLNSIDAEATCVAIRVNMETFQVQVIDNGLGMAGDDVEKVGNRYFTSKCHSVRDLENPAFYGFRGEALASIADMAGAVEISSKKNTTLKTFVKMFQNGKALAT----------HEADLTRPSVGTTVTVYNLFYQFPVRR---KSMDPRLEFEKVRQRVEALSLMHPSISFSLRNDV-----------SGSMVLQLPKTKDICSRFCQIYG-LGKSQKLREIRFKYKEFEFSGYISSEAHYNKNMQFLFVNRRLVLRTKLHKLIDFLLRKESIICRPKNGSASRQMNSSPRHRSASELHGIYVINVQCPFCEYDVCIEPAKTLIEFQSWDTVLICIQEGVKRFLKQEKLFVELSGEDIKEFNEDNGFSLFGTTLQTHVSTHEKCDQSSFREACNKILDSYEMFNLQSKAVKRIATLENKTRQNPGDSETIRKKTVGSL-YTDASDGPCYSKSVESVLQDSNNSAYLEPRVSEEEVAKTSHSGENEKWKKSFLENKTSGRIHETSPKMFSSPIQMHHLLEEREADLEMQTISSTVNVMAANIPQNNDIPSQLEKWKDAPEVGCQPLPFETTLLRVRGTQRKKERRKKEPSSRGRVNVFSYGQVKLCSTGFITHVVQSEHAKSTETEHSFKNYARPGPVSAQETFGKRTHHAIETPDSSDLTSTLSKESSQPPNKRFCRTNTGYGTENKPVATDDNLALFQESCKESHTDRLLPDAS-SFPWCRYVSDGCRKIDKRGSF-KQVVRRKLSLRSQVGSLEKFKRQYGKVSSSLDTEKDNNTEVRTHLDPQNEPDVLLKDKSHLDMSDGCEITTVEHSET---CQPLSPILYPEKILFSKED--RLEQMPHLRESPITLEELSHCNRK-ADVEKSAASLASKLSKLK-DSEKEMQTVGMTGHTSELPDSNPSWKDNSQCTRLDLDFCELLKNKLEKIESDMLPMADSATEDGPINKNSELHPN-NTTDDTEKPETPLLFPCNDSKIS-RDSDVLIRTSEQPTGNPDSVGKVIMSQVEDGIGSQGGVCPQGDESKARSCSKNE-PNAHCMDWQQHFDVTLGRMVYINRMTGLSTFVAP-TDDLHTACTKDLTTVAVDVLLGNGAQYRCHPFRSDLVLPFLPRAQEERTMLR-HNSNAVDAAAAAVSEPLQSLFSEWSNPVFARYPEVAVDVSSGQAESLAVKIHNVLYPYRFTKEMIHSVKVLQQVDNKFIACLMSTRMDEDGR-------TGGNLLVLVDQHAAHERIRLEQLITDSYEKQDPQSAGRKKLLSSTIIPPLAITVSEEQRRLLRSYHKHLEDLGLELLFPD--ASDSLILVGKVPLCFVEREASELRRGRSTVTKSIVEELIREQVELLQTTGG------------IQGTLPLTVQKVLASQACHGAIKFNDRLSLEESCRLIEALSLSQLPFQCAHGRPSMLPLADLDHLEQEKQV-KPNLAKLRKMVRAWHLFGKTE-----QNLQQPIRPCEPP", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9UHC1-1", "uniprot_id": "MLH3_HUMAN", "id": "Q9UHC1-1", "name": "DNA mismatch repair protein Mlh3", "aln": "---MIKCLSVEVQAKLRSGLAISSLGQCVEELALNSIDAEAKCVAVRVNMETFQVQVIDNGFGMGSDDVEKVGNRYFTSKCHSVQDLENPRFYGFRGEALANIADMASAVEISSKKNRTMKTFVKLFQSGKALKA----------CEADVTRASAGTTVTVYNLFYQLPVRR---KCMDPRLEFEKVRQRIEALSLMHPSISFSLRNDV-----------SGSMVLQLPKTKDVCSRFCQIYG-LGKSQKLREISFKYKEFELSGYISSEAHYNKNMQFLFVNKRLVLRTKLHKLIDFLLRKESIICKPKNGPTSRQMNSSLRHRSTPELYGIYVINVQCQFCEYDVCMEPAKTLIEFQNWDTLLFCIQEGVKMFLKQEKLFVELSGEDIKEFSEDNGFSLFDATLQKRVTSDERSN---FQEACNNILDSYEMFNLQSKAVKRKTTAENVNTQSSRDSEATRKNTNDAFLYIYESGGPGHSKMTEPSLQNKD-SSCSESKMLEQETIVASEAGENEKHKKSFLEHSSLENPCGTSLEMFLSPFQTPCHFEESGQDLEIWKESTTVNGMAANILKNNRIQNQPKRFKDATEVGCQPLPFATTLWGVHSAQTEKEK-KKESSNCGRRNVFSYGRVKLCSTGFITHVVQNEKTKSTETEHSFKNYVRPGPTRAQETFGNRTRHSVETPDIKDLASTLSKESGQLPNKKNCRTNISYGLENEPTATYTMFSAFQEGSKKSQTDCILSDTSPSFPWYRHVSNDSRKTDKLIGFSKPIVRKKLSLSSQLGSLEKFKRQYGKVENPLDTEVEESNGVTTNLSLQVEPDILLKDKNRLENSDVCKITTMEHSDSDSSCQPASHILNSEKFPFSKDEDCLEQQMPSLRESPMTLKELSLFNRKPLDLEKSSESLASKLSRLK-GSERETQTMGMMSRFNELPNSDSSRKDSKLCSVLTQDFCMLFNNKHEKTENGVIPTSDSATQDNSFNKNSKTHSNSNTTENCVISETPLVLPYNNSKVTGKDSDVLIRASEQQIGSLDSPSGMLMNPVEDATGDQNGICFQSEESKARACSETEESNTCCSDWQRHFDVALGRMVYVNKMTGLSTFIAP-TEDIQAACTKDLTTVAVDVVLENGSQYRCQPFRSDLVLPFLPRARAERTVMRQDNRDTVD--DTVSSESLQSLFSEWDNPVFARYPEVAVDVSSGQAESLAVKIHNILYPYRFTKGMIHSMQVLQQVDNKFIACLMSTKTEENGE-------AGGNLLVLVDQHAAHERIRLEQLIIDSYEKQQAQGSGRKKLLSSTLIPPLEITVTEEQRRLLWCYHKNLEDLGLEFVFPD--TSDSLVLVGKVPLCFVEREANELRRGRSTVTKSIVEEFIREQLELLQTTGG------------IQGTLPLTVQKVLASQACHGAIKFNDGLSLQESCRLIEALSSCQLPFQCAHGRPSMLPLADIDHLEQEKQI-KPNLTKLRKMAQAWRLFGKAE-CDTRQSLQQSMPPCEPP", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M2B931-1", "uniprot_id": "A0A8M2B931_DANRE", "id": "A0A8M2B931-1", "name": "", "aln": "---MIKSLPINVQAQLRSGVAIFSLQQCVEELILNSIDAGATCVAVKIDIEACKLQVIDNGSGMCLEDMEKVGLRYNTSKCSSLEDLDNLHFYGFRGEAISSIVSLAEMVEISSRTKQSVKTYVKSFNETNALEV----------FEAQTVRPSAGTTVSVYNLFHNMPVRR---KRMDPVLETERIRQRVEAISLMHPSVSFTVKKEN-----------SAHMMVQLSKTSSTYYRFVQIHG-LNRAQKLGEVNYEHEQFQITGHIGREGHYNNSLQFLFVNERLLLKTRIHKTLNCLLKRVSGAARQNNSPTSYPVTSSPKQKGGYDLHGIYVINIKCHYSEYDICLEPAKSLIEFKDWDNVLICIEEGVKAFLTKENLVSELN-----TISNDG---------------------------------------LPCSPVRNAESSEKQKRSSEETN-----------------------EACETMIEKND---------------------------------------------------------------------SSVVDVADG--VQMLEQESIYTESDEGKALQSEDLPFQTTLVGAAEINNNHEE----------------DENAVCSN--ISHTDS--------------------PLAVNKNVMGSKSHKISLPEAQDSLQKFYTPNKTSPKKRRMPLN----------DTEEEKHVFYGGPSKT--------------------------------FKATPPRKLTLSFETGSLDKFKRLFGK-----EAEKKQPSTEKTSLLNPNPNDRFVGSTSCLD-------------------DLHHPVLRNSS------------GHPTTHRS----TESSSLNKK------NKISLAAKCSYLKQDKELCRDSNFLKRDLSSFPPSQDSCFKELEKTLLDEDVLFGSSGIVDSVD---FPLIEQDTALPSVAEESHLFNN-----------NVTFFIGNESSVD-----------------------------EASVASQRDPQHSIAGNEGQTTNESVESIPVSNSWLAHYDSWLGKLVYINQVTGLSKYNSPPMEETQVPCTTDVTNMAVSVISKAGFEYRCYPFQSDIVLPFLPKPRAERAFNS--GTDSRE--DAQAPDSLSTLFSEWHNPVFIRPPEVAVDVTSGQAEGLAVKIHNILFPYRFTKNMIHTMRVINQVDKKFLACLINTAGQNTSES----STDEGNLLVLVDQHAAHERVRLEGLIADSYE-DDPDTPGKKRLCSSRVTPPLEINVTEEELRLLRSCQGFLRGLALDVRFPK--SESLSVFLESLPACFIEKESTELRRGRRSVIKTIAEDYLREHIELLRSTGR------------VRGILPLTVHNVLASQACHGAIKFNDVLNKEECCSLVSSLSSCRLPFQCAHGRPSIVPLADLHHLEEQQDIPKPNLKKLRRMYKSWQLYGQNQ------YFAQNKA-----", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q12083-1", "uniprot_id": "MLH3_YEAST", "id": "Q12083-1", "name": "DNA mismatch repair protein MLH3", "aln": "MSQHIRKLDSDVSERLKSQACTVSLASAVREIVQNSVDAHATTIDVMIDLPNLSFAVYDDGIGLTRSDLNILATQNYTSKIRKMNDLVTMKTYGYRGDALYSISNVSNLFVCSKKKDYNSAWMRKFPSKSVMLSENTILPIDPFWKICPWSRTKSGTVVIVEDMLYNLPVRRRILKEEPPFKTFNTIKADMLQILVMHPMISLNVQYTDKLRINTEVLFRSKNITEGLTKHQQMSQVLRNVFGAIIPPDMLKKVSLKFNEYQIEGIISKMPVGLKDLQFIYINGRRYADSAFQGYVDSLFQAQDFGEKGMSLLKTKSVGKPYRS------HPVFILDVRCPQTIDDLLQDPAKKIVKPSHIRTIEPLIVKTIRSFLTFQGYLTPDK----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SDSSFEIVNCSQKTATLPDSRIQISKR-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------NQVLNSKMKIAR----------------------------------INSYIGKPAVN--------------------------------------------------------------------------------------------------------------------------------GCRINNSTINYEKIKN-------------------------------------------IRIDGQKSRLR----------NKLSSRPYDSGFTEDYD-----------------------SIGKTITDFSISRSVLAKYEVINQVDKKFILIRCLDQSIHNCP-----------LLVLVDQHACDERIRLEELFYSLLTEVVTG------TFVARDLKDCCIEVDRTEADLFKHYQSEFKKWGIGYETIEGTMETSLLEIKTLPEMLTSKYNGDKDYLKMVLLQHAHDLKDFKKLPMDLSHFENYTSVDKLYWWKYSSCVPTVFHEILNSKACRSAVMFGDELTRQECIILISKLSRCHNPFECAHGRPSMVPIAELK------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *: * :*. :*:* . ** ..*.*: **:** *. : : ::: .. * *:* *: .*:: :. : *** .:.** . **:**:*: .* .:: . *.:.. . * .. * . *.. **.* * ::::::**** * * : :: : : :*** :*:.:: * : *.* .. : ::.* : .: * :: :.::::: * *. :.:**:::* * : :: :: *:: . : . : : .. : : :::::::* *: :***.::: . .: : : :: **. : . . . . : .. .: .:: * :* . : : . . * . .. : ::: . . .: *:* : .* : : : ::: :: . .*::***:**: *********..**:*** *: . . : * * . : *: : :. .: . . : : .:* : .: : : : : : ::: : : . :* ..:::* *:**:.*: *.* *. :*. *:. ** .: **:*******::*:*::. ", "identical_positions": 122, "similar_positions": 238, "identity": "8.06%" }, { "cls_id": "homologset.agr.MGI:1353460", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q00688-1", "uniprot_id": "FKBP3_HUMAN", "id": "Q00688-1", "name": "Peptidyl-prolyl cis-trans isomerase FKBP3", "aln": "MAAAVPQRAWTVEQLRSEQLPKKDIIKFLQEHGSDSFLAEHKLLGNIKNVAKTANKDHLVTAYNHLFETKRFKGTESISKVSEQVKNVKLNEDKPKETKSEETLDEGPPKYTKSVLKKGDKTNFPKKGDVVHCWYTGTLQDGTVFDTNIQTSAKKKKNAKPLSFKVGVGKVIRGWDEALLTMSKGEKARLEIEPEWAYGKKGQPDAKIPPNAKLTFEVELVDID---------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q62446-1", "uniprot_id": "FKBP3_MOUSE", "id": "Q62446-1", "name": "Peptidyl-prolyl cis-trans isomerase FKBP3", "aln": "MAAAVPQRAWTVEQLRSEQLPKKDIIKFLQDHGSDSFLAEHKLLGNIKNVAKTANKDHLVNAYNHLFESKRFKGTETISKVSEQVKNVKLSDDKPKDSKSEETLDEGPPKYTKSILKKGDKTNFPKKGDVVHCWYTGTLPDGTVFDTNIQTSSKKKKNAKPLSFKVGVGKVIRGWDEALLTMSKGEKARLEIEPEWAYGKKGQPDAKIPPNTKLIFEVELVDID---------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8I6AGJ8-1", "uniprot_id": "A0A8I6AGJ8_RAT", "id": "A0A8I6AGJ8-1", "name": "peptidylprolyl isomerase", "aln": "MAAAVPQRAWTVEQLRSEQLPKKDIIKFLQDHGSDSFLAEHKLLGNIKNVAKTANKDHLVTAYNHLFESKRFKGTETISKVSEQVKNVKLNDDKQKDSKSEETLDEGPPKYTKSVLKKGDKTNFPKKGDVVHCWYTGTLPDGTVFDTNIQTSSKKKKNAKPLSFKVGVGKVIRGWDEALLTMSKGEKARLEIEPEWAYGKKGQPDANCPQHVRHGLLWEMNSTGSAEDMPHSFNAVVFHVLGILHTENRKY", "tax_id": 10116, "tax_name": "Rat" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "******************************:*****************************.*******:*******:*************.:** *::****************:************************ ************:*****************************************************: * :.: : *: . . ", "identical_positions": 196, "similar_positions": 18, "identity": "78.09%" }, { "cls_id": "homologset.agr.MGI:1353466", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8M6YV12-1", "uniprot_id": "A0A8M6YV12_DANRE", "id": "A0A8M6YV12-1", "name": "", "aln": "---MSWLWPWILLF------WMLKMDSVRTSRVALQ-SCTQEDFQHAEEYLRHFYHLKMRVYN--KRRAER----MKDKIRAMQHFFDLKETAFLDHKTLNGMKEARCGVPDVENFSFYPGRPKWKSNIITYRIARFTPDLR------------------PEEVENSLHLALKIWSDAAPLKFVQIKEGRADITFSFNSKAHGDFFPFDGPGGVLAHAFEPGEGLGGDVHFDDDEIWTVGRGRP---GYNLFTVAAHELGHSLGLSHSKDPTALMYPKYKFINAATYKLPRDDTLGIQALYGKKTRQQE-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------LVIPNKCD-VISFDAVTVLEKEIIFFKNSYMWMRTNWRSYW-NRLKEGPQSVFLPSIPSPIDAAYDIPSQRVAYVFTGPKYWVVQKLESKSYYYGSIYEFGFPEIVRQIDAAVHVSEGGKTYFFTGDYYFSYDEKRNVMDRGFPRKINTGWPGIVGKVDAAFELNGRVHLFCRSKSFIFSH-QKRLLHTMNTN---AWLGCS--------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "E7F3C3-1", "uniprot_id": "E7F3C3_DANRE", "id": "E7F3C3-1", "name": "", "aln": "---MQVLLCLVCAFDLFGQHYSLPLPLGDDGMVHPT-KPAQNDLSLATKYLQQFYSFQADSAG--RKRRSRPS--FSSKLKNMQGFFGLNGTGTLNADTLAVMRTPRCGVSDVEDYSHRRGN-RWKKNIITYGVGRYTNDLP------------------VNAVDDLISSALDVWAKASPLTFLRSYSHQADIMVEFVGKEHGDFFPFDGPDGTLAHAFGPGEGIGGDVHFDEAEVWTAGYN-----GFNLYVVAAHEFGHALGLKHSQLPESVMYPTYKRR-KTHNLLSSEDIININTLYGPRDKRPYPSS----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------RFSWSNPSTPWYSGSYFPVSFKDTCNPHLKFDAVTTVGDAIFFFRDNYMWIKHNDQ----KDIKEGPISNFMPKIDCHIDAAYWVPQRSTAYLFNGTTFWTVKGSQVKGRAKN-ISSLGFPSWVQQVDAAVHIHKTVHTLFFTQHQYWRYNEHNKNMTDSIPRNISDDFPEISGPISAAIYKDGYLHFFIGSDVYKYDIKQKEIIGTDKTT---SWLGC---------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P57748-1", "uniprot_id": "MMP20_MOUSE", "id": "P57748-1", "name": "Matrix metalloproteinase-20", "aln": "---MKVLPASGLAV----LVTALKFATADPNLLAATPRTFRSNYHLAQAYLDKYYTKKGGPQA--GEMVARESNPMIRRIKELQIFFGLKVTGKLDQNTMNVIKKPRCGVPDVANYRLFPGEPKWKKNILTYRISKYTPSMS------------------PTEVDKAIQMALHAWSTAVPLNFVRINSGEADIMISFETGDHGDSYPFDGPRGTLAHAFAPGEGLGGDTHFDNAEKWTMGTN-----GFNLFTVAAHEFGHALGLGHSTDPSALMYPTYKYQNPYRFHLPKDDVKGIQALYGPRKIFPG------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------KPTMPHIP--PHKPSIPDLCDSSSSFDAVTMLGKELLFFKDRIFWRRQVHLP---TGIRPSTITSSFPQLMSNVDAAYEVAERGIAFFFKGPHYWVTRGFHMQGPPRT-IYDFGFPRHVQRIDAAVYLKEPQKTLFFVGEEYYSYDERKKKMEKDYPKNTEEEFSGVSGHIDAAVELNGYIYFFSGRKTFKYDTEKEDVVSVVKSS---SWIGC---------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D3ZXD9-1", "uniprot_id": "D3ZXD9_RAT", "id": "D3ZXD9-1", "name": "", "aln": "---MKVLPASGLAV----LVTALKFATAAPALLAATPRTFRSNYHLAQAYLDKYYTKKGGPQA--GEMVARESNPTVRKIKELQTFFGLRVTGKLDQNTMDVIKRPRCGVPDVANYRLFPGEPKWKKNILTYRVSKYTPSMS------------------PTEVDKAVHMALHAWSTAVPLIFVRINSGEADIMISFETGDHGDSYPFDGPRGTLAHAFAPGEGLGGDTHFDNAEKWTMGTN-----GFNLFTVAAHEFGHALGLGHSTDPSALMYPTYKYQNPYRFHLPKDDVKGIQALYGPRKTFPG------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------KPTMPHIP--PHKPSIPDLCDSSSSFDAVTMLGKELLFFKDRIFWRRRVHLP---AGIRPSTITSSFPQLMSNVDAAYEVAERGIAFFFKGPHYWVTRGFQMQGPPRT-IYDFGFPRHVQRIDAAVYLKEPQKTLFFVGEEYYSYDERKKKMEKDYPKSTEEEFSGVSGHIDAAVELNGYIYFFSGPKTFKYDTEKEDVVSVVKSS---SWVGC---------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O60882-1", "uniprot_id": "MMP20_HUMAN", "id": "O60882-1", "name": "Matrix metalloproteinase-20", "aln": "---MKVLPASGLAVF---LIMALKFSTAAPSLVAASPRTWRNNYRLAQAYLDKYYTNKEGHQI--GEMVARGSNSMIRKIKELQAFFGLQVTGKLDQTTMNVIKKPRCGVPDVANYRLFPGEPKWKKNTLTYRISKYTPSMS------------------SVEVDKAVEMALQAWSSAVPLSFVRINSGEADIMISFENGDHGDSYPFDGPRGTLAHAFAPGEGLGGDTHFDNAEKWTMGTN-----GFNLFTVAAHEFGHALGLAHSTDPSALMYPTYKYKNPYGFHLPKDDVKGIQALYGPRKVFLG------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------KPTLPHAP--HHKPSIPDLCDSSSSFDAVTMLGKELLLFKDRIFWRRQVHLR---TGIRPSTITSSFPQLMSNVDAAYEVAERGTAYFFKGPHYWITRGFQMQGPPRT-IYDFGFPRHVQQIDAAVYLREPQKTLFFVGDEYYSYDERKRKMEKDYPKNTEEEFSGVNGQIDAAVELNGYIYFFSGPKTYKYDTEKEDVVSVVKSS---SWIGC---------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8MPP3-1", "uniprot_id": "D2MP_DROME", "id": "Q8MPP3-1", "name": "Matrix metalloproteinase-2", "aln": "MFSKYVLATLLALFAQSMCIQELSLPPEGSHSTAATRSKKAKTAISEDIMYNYLMQFDYLPKSDLETGALRTEDQLKEAIRSLQSFGNITVTGEIDSATARLIQKPRCGVGDRRSADSFSPDNLYHEIGSNVRVRRFALQGPKWSRTDLTWSMVNRSMPDASKVERMVQTALDVWANHSKLTFREVYSDQADIQILFARRAHGDGYKFDGPGQVLAHAFYPGEGRGGDAHFDADETWNFDGESDDSHGTNFLNVALHELGHSLGLAHSAIPDAVMFPWYQNNEVAGN-LPDDDRYGIQQLYGTKEKTWGPYKPQTTTTTTTTTTMRAMIYRADKPAYWPWNNPSNNPNNDRNRARERQEEERRRQEKERRRQEEERRHQEEERRRQVEERQRQEEERWRQEQERQEEENRRRKIEHKSQWERNPSKERNRPRERQEMERRRQEQERQEQERQEQEDRRRERERDRQLEWERRNRNGAREPVTPTANTTPRPTNKPYPTVHRQHHHHNKPRKPKPDSCMTYYDAISIIRGELFIFRGPYLWRIGTSGLYNGYPTEIRRHWSALPENLTKVDAVYENKQRQIVFFIGREYYVFNSVMLAPGFPKP-LASLGLPPTLTHIDASFVWGHNNRTYMTSGTLYWRIDDYTGQVELDYPRDMSIWSGVGYNIDAAFQYLDGKTYFFKNLGYWEFNDDRMKVAHARAKLSARRWMQCARSANEVDDEQRWTASLVSEGEETGRSGSRELRINHFILSILLLAIANWRS", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * . * : . . * :: :* * .: *. :: * :: .**** * . ::. . : ::: . *: : **. *: * * . . .*** . * *** : **** .***** **** ***.*** * *. . * *: ** **:**:*** ** * ::*:* *: *. :* .*: *** : . . :**:: : :::*:. :* . :*. :**.* .: .:.: : . : .:*:* : ::**:. . :* : *: :: : . *:. . . * :* ::* : :. : : . . *: * ", "identical_positions": 89, "similar_positions": 107, "identity": "11.71%" }, { "cls_id": "homologset.agr.MGI:1353467", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q2IBD4-1", "uniprot_id": "CTTB2_RAT", "id": "Q2IBD4-1", "name": "Cortactin-binding protein 2", "aln": "MATDSASCEPDLSRAPGDAEGATAEAAKKEFDVDTLSKSELRMLLSVMEGELEARDLVIEALRARRKEVFIQERYGRFNLNDPFLALQRDYEAGAGDKEK-PVCTNPLSILEAVMAHCRKMQERMSAQLAAAESRQKKLEMEKLQLQALEQEHKKLAAHLEEERGKNKHVVLMLVKECKQLSGKVVEEAQKLEEVMVKLEEEKKKTSELEDQLSAEKQRSAGMEAQLEKQLFEFDTEREQLRAKLTREEAHTTDLKEEIDKMKKMMEQMK--KGNDGKPGLSLP---RKTKDKRLASISVATEGPVTRSVACQTDVVTESTDPVKKLPLSVPIKPSTGSPLVSTNTKGNVGPSALLIRPGIDRQASHSDLG-PSPPTALPSSASRIEENGPSAGNAPDLSNSTPSTPSGTAPAAAQTLGAAPQNHSQAPPVHSLHSPCANT--HPGLNPRIQAARFRFQGNANDPDQNGNNTQSPPSRDVSPTSRDNLVAKQLARNTVTQALSRFTSPQAG---ASSRLGASPGGDAGTCPPVGRT-----GLKTPGAARVDRGNP-PPIPPKKPGLSQTPSPPHPQL-------RASNAGAKVDNKIVASPPSTLPQGTKVVNEENVPKSSSPQLPPKPSIDLTVASAGCPVSALATSQVGAWPAETPGLNQP--ACTDSSLVIP---TTVAFRSSINPVSASSRSPGASDSLLVTASGWSPSLTPLLMSGGPAPLAGRPTLLQQAAAQGNVTLLSMLLNEE-GLDINYCCEDSHSALYSAAKNGHTDCVRLLLNAEARVDAADKNGFTPLCVAAAQGHFECIELLTAYNANINHSAAGGQTPLYLACKTGNKECIKLLLEAGTDRSIKTRDGWTPIHAAVDTGNVDSLKLLMYHRVPAPGNSLSAEEPKSGLFSLNGGE-SPPGSSKPVVPADLINHADKEGWTAAHIAASKGFKNCLEILCRHGGLEPERRDKCNRTVHDVATDDCKHLLENLNALKIPLRISVGEIQPSNDGSDDFECEHTICTLNIRKQTSWEDFSKAVSQALTNHFQAISSDGCWGLEDGTLNNTTDSCIGLGTSSIQSIMLGSIPWSTGQSFSQSPWDFMKKKKVEQVTVLLSGPQEGCLSSVTYTSMIPLQMLQNYLRLVEQYHNVIFHGPEGSLQDYIANQLALCMKHRQMAAGFPCEIVRAEVDSGFSKEQLVDVFISNACLIPVKQFPVKKKIIVILENLEKS-SLSELLGDFLAPLENRSTESPCTFQKGNGTSECYYFHENCFLLGTLAKACLQGSDLLVQQHFRWVQLRWDCEPSQGLLQRFLRRKAVSKFRGQLPAPCDPVCKIVDWVISVWRQLNSCLARLGTPEALLGPKYFLSCPVVPGHAQATVKWMSKLWNAIIAPRVQEAILSRAAMNKQPGARQTASKKHPSQGQQAVVRAALSILLNKAILHGCPLPRTELDQQIADFKGGSFPLSIVSSYS---KKKGESAAWRKVNTSPRKKPGHFSSPMWNKPDLKHEGMRNKSVPHLNINRSSSLSKQQSLENDLSMTLTLDHRLSLGSDDEADLVKELQSMCSSKSESDISKIADSREDLRTFD--SSRTNPVTSAPVN-LRMPVPQKEASPLSSHQTTECSNSKSKTELGVSRVKSFLPVPRSK-----VAQCS--QNTKRSSSSSSNTRQLEINNNS----KEENWNVDKHEHVEKRNK-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "B9EJA2-1", "uniprot_id": "CTTB2_MOUSE", "id": "B9EJA2-1", "name": "Cortactin-binding protein 2", "aln": "MATDSASCEPDLSRTPGDTEGATAEAAKKEFDVDTLSKSELRMLLSVMEGELEARDLVIEALRARRKEVFIQERYGRFNLNDPFLALQRDYEAGPGDKEK-PVCTNPLSILEAVMAHCRKMQERMSAQLVAAESRQKKLEMEKLQLQALEQEHKKLAAHLEEERGKNKHVVLMLVKECKQLSGKVVEEAQKLEEVMAQLEEEKKKTSELEEQLSAEKQRSSGMEAQLEKQLSEFDTEREQLRAKLSREEAHTTDLKEEIDKMKKMMEQMK--KGSDGKPGLSLP---RKTKDKRLASISVATEGPVTRSVACQTDVVTESTDPVKKLPLTVPIKPSTGSPLVPTNTKGNVGPSALLIRPGIDRQSSHSDLG-PSPPTALPSSANRIEENGPSTGNAPDLSNSTPSTPSSTAPAAAQTPGTAPQNHSQAPTVHSLHSPCANT--HPGLNPRIQAARFRFQGNANDPDQNGNNTQSPPSRDVSPTSRDNLVAKQLARNTVTQALSRFTSPQAG---ASSRLGVSPGGDAGTCPPVGRT-----GLKTPGAARVDRGNP-PPIPPKKPGLSQTPSPPHPQL-------RASNAGAKVDNKIVASPPSTLPQGTKVVNEENVPKSSSPQLPPKPSIDLTVAPAGCPVSALATSQVGAWPAGTPGLNQP--ACSDSSLVIP---ATVAFCSSINPVSASSRSPGASDSLLVAASGWSPSLTPLLMSGGPAPLAGRPTLLQQAAAQGNVTLLSMLLNEE-GLDINYSCEDGHSALYSAAKNGHTDCVRLLLNAEARVDAADKNGFTPLCVAAAQGHFECIELLTAYNANINHSAAGGQTPLYLACKNGNKECIKLLLEAGTDRSIKTRDGWTPIHAAVDTGNVDSLKLLMYHRVRAHGNSLSSEEPKSGLFSLNGGE-SPTGPSKPVVPADLINHADKEGWTAAHIAASKGFKNCLEVLCRHGGLEPERRDKCNRTVHDVATDDCKHLLENLNALKIPLRISVGEIQPSNDVSDDFECEHTICTLNIRKQTSWEDFSKAVSQALTNHFQAISSDGWWSLEDGTFNNATDSCIGLGTSSIRSIMLGSMPWSTGQSFSQSPWDFLKKKKVEQVLALLSGPQEGCLSSVTYASMIPLQMLQNYLRLVEQYHNVIFHGPEGSLQDYIANQLALCMKYRQMAAGFPCEIVRAEVDSGFSKEQLVDVFIRNACLIPVKQFPVKKKIIVILENLEKS-SLSELLGDFLAPLENRSTESPCTFQKGNGTSECYYFHENCFLVGTIAKACLQGSDLLVQQHFRWVQLRWDCEPIQGLLQRFLRRKVVSKFRGQLPAPCDPVCKIVDWALSVWRQLNSCLARLGTPEALLGPKYFLSCPVVPGHAQATVKWMSKLWNAVIAPRVQEAILSRASMNKQPGTGQTASKKYPSQGQQAVVRAALSILLNKAVLHGCPLPRAELDQQIADFKGGSFPLSIVSSYS---KKKVESGAWRKVNTSPRKKPGHFSSPTWNKPDPKREGMRNKTIPHLNTNRNSSLSKQQSLENDLSVTLTLDHRLSLGSDDEADLVKELQSMCSSKSESDISKIADSRDDLRKFD--SSRTNPGTSAPLN-LRTPVPQKEASPPSSRQTAECSNSKSKTEMGVSSVKSFLPVPRSK-----VAQCS--QNTKRNSSSS-NTRQLEINNNS----KEENWTLDKHEQVEKPNK-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8WZ74-1", "uniprot_id": "CTTB2_HUMAN", "id": "Q8WZ74-1", "name": "Cortactin-binding protein 2", "aln": "MATDGASCEPDLSRAPEDAAGAAAEAAKKEFDVDTLSKSELRMLLSVMEGELEARDLVIEALRARRKEVFIQERYGRFNLNDPFLALQRDYEAGAGDKEKKPVCTNPLSILEAVMAHCKKMQERMSAQLAAAESRQKKLEMEKLQLQALEQEHKKLAARLEEERGKNKQVVLMLVKECKQLSGKVIEEAQKLEDVMAKLEEEKKKTNELEEELSAEKRRSTEMEAQMEKQLSEFDTEREQLRAKLNREEAHTTDLKEEIDKMRKMIEQLK--RGSDSKPSLSLP---RKTKDRRLVSISVGTEGTVTRSVACQTDLVTENADHMKKLPLTMPVKPSTGSPLVSANAKGSVCTSATMARPGIDRQASYGDLIGASVPAFPPPSANKIEENGPSTGSTPDPTSSTPPLPSNAAPPTAQTPGIAPQN-SQAPPMHSLHSPCANTSLHPGLNPRIQAARFRFQGNANDPDQNGNTTQSPPSRDVSPTSRDNLVAKQLARNTVTQALSRFTSPQAG---APSRPGVPPTGDVGTHPPVGRT-----SLKTHGVARVDRGNP-PPIPPKKPGLSQTPSPPHPQLKVIIDSSRASNTGAKVDNKTVASTPSSLPQGNRVINEENLPKSSSPQLPPKPSIDLTVAPAGCAVSALATSQVGAWPAATPGLNQP--ACSDSSLVIP---TTIAFCSSINPVSASSCRPGASDSLLVTASGWSPSLTPLLMSGGPAPLAGRPTLLQQAAAQGNVTLLSMLLNEE-GLDINYSCEDGHSALYSAAKNGHTDCVRLLLSAEAQVNAADKNGFTPLCAAAAQGHFECVELLISYDANINHAADGGQTPLYLACKNGNKECIKLLLEAGTNRSVKTTDGWTPVHAAVDTGNVDSLKLLMYHRIPAHGNSFNEEESESSVFDLDGGEESPEGISKPVVPADLINHANREGWTAAHIAASKGFKNCLEILCRHGGLEPERRDKCNRTVHDVATDDCKHLLENLNALKIPLRISVGEIEPSNYGSDDLECENTICALNIRKQTSWDDFSKAVSQALTNHFQAISSDGWWSLEDVTCNNTTDSNIGLSARSIRSITLGNVPWSVGQSFAQSPWDFMRKNKAEHITVLLSGPQEGCLSSVTYASMIPLQMMQNYLRLVEQYHNVIFHGPEGSLQDYIVHQLALCLKHRQMAAGFSCEIVRAEVDAGFSKEQLLDLFISSACLIPVKQSPSKKKIIIILENLEKS-SLSELLRDFLAPLENRSTESPCTFQKGNGLSECYYFHENCFLMGTIAKACLQGSDLLVQQHFRWVQLRWDGEPMQGLLQRFLRRKVVNKFKGQAPSPCDPVCKIVDWALSVWRQLNSCLARLGTPEALLGPKYFLSCPVVPGHAQVTVKWMSKLWNGVIAPRVQEAILSRASVKRQPGFGQTTAKRHPSQGQQAVVKAALSILLNKAVLHGCPLPRAELDQHTADFKGGSFPLSIVSSYNTCNKKKGESGAWRKVNTSPRRKSGRFSLPTWNKPDLSTEGMKNKTISQLNCNRNASLSKQKSLENDLSLTLNLDQRLSLGSDDEADLVKELQSMCSSKSESDISKIADSRDDLRMFD--SSGNNPVLSATINNLRMPVSQKEVSPLSSHQTTECSNSKSKTELGVSRVKSFLPVPRSK-----VTQCS--QNTKRSSSSS-NTRQIEINNNS----KEVNWNLHKNEHLEKPNK-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F1QFV1-1", "uniprot_id": "F1QFV1_DANRE", "id": "F1QFV1-1", "name": "Cortactin-binding protein 2", "aln": "MASDGAKGEQPPPLQTLVTTGHGSVEAKCELNIDNLSKPELLTLLSIMEGELEARDLVIEALRARRKEVFLQERYGQFSLTDPFLAMQRDFESGMGPKDRRPVSASPITVLEAVMAHCRKMQEKMSAQLSAAETRQKRLEMEKLQLQSLEQEHRKLSAQLKDEREKNKHVVMSLVHECKQLAARVVEENQRFEELSSRTEQDGRSVGRLEEELASERRRSQQMEAEMEKQLAEFDTEREQLRARLSREETRAVELRAESENLRLQVEQLRTERCKDSPPLPSVTPASVSVKPKAMVSVAVGTEATVCKTVSSQTDAPLENEG-AKKVPLSIPVKPS-GSTYASMNLP-------------------------------KTSSAGRGLHHGSSQ---------------------------AENGGDGQTHLHSSHSPGVSSTLPTGVSPRVQAARYKFQPSASEQDQNGTANQSPPSRDLSPTNRDNFAAKQQARHTVTQVLSRFTSPPAGGPPAALRPGLPHSTSEG-GPFTGRLGHPQIGLKSPTVARIDRGNP-PPIPPKKPGLSQTPSPPHPPI--------------KVVGEASRSPGTGLGVG-------LAKSATTPQLPPKPSLDM-----GGTVPAMTASQVGASCSGWPWGQQPTAACVECPPVITSSTATIVSSPSINPSSLPSHSPQHLGSPLAAASGWCPSIVPSLTCGDPVPLDDGQTLLLQAASQGNVTLLSMLLNQDPLLDIHHHQHELTSALISAAHNGHTDCLNLLLTSGASADAADETGFSPLHAAMQNGHHGCARALVNCGADLEKEYSQGRTPLYLACEQGHVQCVKVLLDAGADRTHVTTDSCTALHAAVSSGHVDTLKLLLHHPSSEPDHLNSPTFPSDAKQEL-----QKPGISK---ACHILNHSNQDGWTAAHIAASRGYKKCLEVLCNHSQHDMERRDKCNRTIHDVATDDCKDLLENLDWYTVVVQVLMGSPERLCP-VDLLEDGCTVGKVTVQRHTSWEELTESLSHLLTNHLQLICGS--WELQDVLAR---ADTLGLSANSIASVIIGDAVWMAGQDLAQSPWDLVRKRLSQRITIRLKGLSECALDEMTYDSLISVQLLQNYVRLVEQYHNVIFHGLEGSFQEYIANQISHYIKHRQEAQGIICDVIRVEIEENLSKEQLLEIFINCGFLVSLHESSAGHCVVVVLEGLERAHSLSHILGDLCEALENRGSVYSLSLN--HGHDGLYYFREGSFLMGTLAKPRLQGAELRLQQHFRWVQLRWDSEPLNGMLGRHMRRKLLHKTQGQCWTSDDPLQKALSWVCSVWHQLNACLSRLGTSEALLGPYIFLSCPVNLEQTQAIPKWLVRLWNAVIVPRVEDAVISRVTAKRSPSQRRSPNSKALTPGQRAVVKAALNILLNKAVLQGCPLPRPEIDRLLPELQGGCFPLSAIGSAY---RKGGRKGAWRRANTSPRKK-GSPASGRSSSCSFREGSLANSSTQSMTNGNHASG-------------------LSLCSDDETDLIRELQSMCSSKSEPDISKIALFKEDFIMLPHSSSASPQGTDGEVNQPQTHSHTADRAVDNTRPPAQQTDSVHTSPRRVMRPRSHLPVPSSRGSQQMISSSSSLQTHSRASTSSSRTRQPPSNNNTNNLSQDHIWFLDPNSNENYSTHG", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q8SX68-1", "uniprot_id": "CT2NL_DROME", "id": "Q8SX68-1", "name": "CTTNBP2 N-terminal-like protein", "aln": "---MEQNSNSSVADTFAEAPATDADYGTENCSGSGMSVGDTVSANHEFQTMKPGPGVVHKVMPVANSASSATATNGRTRSEMPHSELVKMLYYLEGELQARDVCIAALRNERVKQLIAQLRTKRLQPNDPYAAIFRDKIALNGNLIS------RESSTQAAQAEMEVRQIIEQQMEQQYQMVSKQRATHVRMVNILTESLENNQ---RMLQELEEEKRKHENTTAQGDDITYGLELERNKLKQDLEEERAQVAKMEKDLKKLQETLEYER--NRQKQIVLLLIAERKKILMKYIEEGKRSEDLAQILAEEKQRSDTIAEGLEEESKKSLRMEEELEKQTHAMEQERK------------------------------VLFAKLAKEELR-------------------------------VKELEQELNALRSEHEALKKQQQLGGSGSSVAAAKARQFS--------DDACATPPMVNIAKIVQPTATVSSMPVSGPQTGIARSIAPGQN-------------------------------IRSAGIATAPTGTATAAIAPLTAVLNHTTTITTTTN----------------------------------------NTTTSSNSNSSGSIG-----VAATAAAVAASVETAATVTVPMVAPP-----------------SPSPAKMQPTATIQRAPGGKYAALAAAAALDQTTTPHPH---PVPIAVPPVTVPPAGARG---------------------------------------APPPIPTKPIVPPKREPSLSRLGSITGSSAIAAATAATTAAGTAKQN---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . : . : . : .. : . . :* : :: . .:* :.: . .. *: *. : : * : *. .: .. .: :::..: * :.:: :: :. :: ::: : . : :::: :.: *: .: :: :: . :: : .: ::* *::: *: :. :: **::*: * .*.::...:. : .::: :* : . .. :. . . : ::* *. .* .* : : . : : .. : . . : . ::* *.. . * .. : **: : . :** ::: : . .... . ::* :* . ::: * *.. ..*.* .. *.:*.: . . .:::.: .. *:. . ...*:::* * * * ..::* : . * : *.:*:. : .* *.*: . : *.::* : : . . . : .:: * .. . . :: ", "identical_positions": 52, "similar_positions": 226, "identity": "3.06%" }, { "cls_id": "homologset.agr.MGI:1353468", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D4AAT1-1", "uniprot_id": "D4AAT1_RAT", "id": "D4AAT1-1", "name": "", "aln": "MLRDPTATRWPPLLLLLLQLPPPPLVCGAPARPGTRTQASELVVPTRLPSSA---------SELAFHLSAFGQSFVLRLAPDASFLAPEFKIERLGGS----------------------------------------------SAAAGGEP-----------GLRGCFFSGTVNGE---------------------RESLAAMSLCGG--LSGSFLLAGEEFTIQPQG----AGDSLDQPHRLQRWG----PGQRREDPGLAAAEVFPLPQGLEWEVEMGDGQGQRRRDNEEDRERDKEGLRKETEDSREVTPPFGSKTRSKR-FVSEARFVEILLVADASMAAFYGTDLQN--------HILTVMSMAARIYKHPSIRNSINLVVVKVLIVEEEG-WGPEVSDNGGLTLRNFCSWQRRFNKPSDRHPEHYDTAILFTRQNFCRKGEQ---CDTLGMADVGTICDPNKSCSVIKDEGLQAAYTLAHELGHVLSMPHDDSKPCVRLFGPMGKYHMMAPFFIHVNKTLPWSPCSAVYLTELLDDGHGDCLLDAPTSVLPLPTGLPGHST--LYELDQQCKQIFGPDFRHCPNTSVEDICVQLWCR----HRDSDEPICHTKNGSLLWADGTPCGPGHLCLDGSCVL------------------------------REEVENPKAVVDGDWGPWGPWGQCSRTCGGGIQFSNRECDN------PAPQNGGRFCLGERVKYQSCKTEECPPN-GKSFREQQCEKYNAYNHTDLDGN-FLQWVPKYSGVSPRDRCKLFCRARGRSEFKVFETKVIDGTLCGPDTLAICVRGQCVKAGCDHVVNSPKKLDKCGVCGGKGTACRKVSGSFTPFSYGYNDIVTIPAGATNIDVKQRSHPGVQNDGSYLALKTANGQYLLN---GNLAISAIEQDILMKGTILKYSGSMATLERLQSFQALPEPLTVQLLTVSGEVFPPK-------VKYTFFVPNDTDFNVQSSKE---RASTNIIQSLPYAEWVLGDWSECPSTCGGGWQRRTVECRD---PSGQASDTCDEALKPEDAKPCGSQPCLL---------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P57110-1", "uniprot_id": "ATS8_MOUSE", "id": "P57110-1", "name": "A disintegrin and metalloproteinase with thrombospondin motifs 8", "aln": "MLRDPTTTGWPPLLLLLLQLPPPPLVCGAPAGPGTGAQASELVVPTRLPGSA---------SELAFHLSAFGQGFVLRLAPDASFLAPEFKIERLGGS----------------------------------------------SAAAGGEP-----------GLRGCFFSGTVNGE---------------------RESLAAMSCVAG--WSGSFLLAGEEFTIQPQG----AGDSLDQPHRLQRWG----PGQRREDPGLAAAEVFPLPQGLEWEVEMGNGQGQERSDNEEDRKQDKEGLLKETEDSRKVPPPFGSKTRSKR-FVSEARFVETLLVADASMAAFYGTDLQN--------HILTVMSMAARIYKHPSIRNSVNLVVVKVLIVEKER-WGPEVSDNGGLTLRNFCSWQRRFNKPSDRHPEHYDTAILFTRQNFCGKGEQ---CDTLGMADVGTICDPDKSCSVIKDEGLQAAYTLAHELGHVLSMPHDDSKPCVRLFGPMGKYHMMAPFFIHVNKTLPWSPCSAVYLTELLDDGHGDCLLDAPTSVLPLPTGLPGHST--LYELDQQCKQIFGPDFRHCPNTSVEDICVQLCAR----HRDSDEPICHTKNGSLLWADGTPCGPGHLCLDGSCVL------------------------------KEDVENPKAVVDGDWGPWRPWGQCSRTCGGGIQFSNRECDN------PMPQNGGRFCLGERVKYQSCNTEECPPN-GKSFREQQCEKYNAYNHTDLDGN-FLQWVPKYSGVSPRDRCKLFCRARGRSEFKVFEAKVIDGTLCGPDTLSICVRGQCVKAGCDHVVNSPKKLDKCGVCGGKGTACRKISGSFTPFSYGYNDIVTIPAGATNIDVKQRSHPGVRNDGSYLALKTANGQYLLN---GNLAISAIEQDILVKGTILKYSGSMATLERLQSFQALPEPLTVQLLTVSGEVFPPK-------VRYTFFVPNDMDFSVQNSKE---RATTNIIQSLPSAEWVLGDWSECPSTCRGSWQRRTVECRD---PSGQASDTCDEALKPEDAKPCGSQPCPL---------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9UP79-1", "uniprot_id": "ATS8_HUMAN", "id": "Q9UP79-1", "name": "A disintegrin and metalloproteinase with thrombospondin motifs 8", "aln": "MLPAPAAPRWPPLLLLLLLLLP--LARGAPARPAAGGQASELVVPTRLPGSA---------GELALHLSAFGKGFVLRLAPDDSFLAPEFKIERLGGS----------------------------------------------GRATGGER-----------GLRGCFFSGTVNGE---------------------PESLAAVSLCRG--LSGSFLLDGEEFTIQPQG----AGGSLAQPHRLQRWG----PAGAR-----------PLPRGPEWEVETGEGQRQERGDHQEDSE--EESQEEEAEGASEPPPPLGATSRTKR-FVSEARFVETLLVADASMAAFYGADLQN--------HILTLMSVAARIYKHPSIKNSINLMVVKVLIVEDEK-WGPEVSDNGGLTLRNFCNWQRRFNQPSDRHPEHYDTAILLTRQNFCGQEGL---CDTLGVADIGTICDPNKSCSVIEDEGLQAAHTLAHELGHVLSMPHDDSKPCTRLFGPMGKHHVMAPLFVHLNQTLPWSPCSAMYLTELLDGGHGDCLLDAPAAALPLPTGLPGRMA--LYQLDQQCRQIFGPDFRHCPNTSAQDVCAQLWC-----HTDGAEPLCHTKNGSLPWADGTPCGPGHLCSEGSCLP------------------------------EEEVERPKPVADGGWAPWGPWGECSRTCGGGVQFSHRECKD------PEPQNGGRYCLGRRAKYQSCHTEECPPD-GKSFREQQCEKYNAYNYTDMDGN-LLQWVPKYAGVSPRDRCKLFCRARGRSEFKVFEAKVIDGTLCGPETLAICVRGQCVKAGCDHVVDSPRKLDKCGVCGGKGNSCRKVSGSLTPTNYGYNDIVTIPAGATNIDVKQRSHPGVQNDGNYLALKTADGQYLLN---GNLAISAIEQDILVKGTILKYSGSIATLERLQSFRPLPEPLTVQLLTVPGEVFPPK-------VKYTFFVPNDVDFSMQSSKE---RATTNIIQPLLHAQWVLGDWSECSSTCGAGWQRRTVECRD---PSGQASATCNKALKPEDAKPCESQLCPL---------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9QEM5-1", "uniprot_id": "A0A8M9QEM5_DANRE", "id": "A0A8M9QEM5-1", "name": "", "aln": "------MVSTIVYVFFLVNLMSQFALCELNEEEET-VLVNRTFRKGLFWRSE---------ERQHFKLSAFGHLFLLDLSPDSKFVSPVLNVQRIKAKNLRSVL---------------------------------------DASRSGGALRDATLYPDSGADLRDCFYTGTVNSE---------------------KESVVAVSLCHG--IHGTFITQGVEYFIHPKASVQTTGKHFPQVHVIKRRA----VSNSR-------------TASLVFDQMKVDSLVKESKLNS-----------SEDEDS--------NMRRAKR-FVSAARYIETLVVADASMTRFYGDEIKH--------YLLTVMAMAAQVFVHPSLKNAVSLVVVKMVVVEDEE-VGPELSSNGGVALRNFCMWQQLFNPGSQRHPEHYDTAILFTREDICGYKD----CDTLGVADVGTMCDPKRSCSVIEDNGLQAAFTVSHELGHVLSMPHDDSKNCEKWFGHLYG-HTMAPFFVHLNKTLPWSPCSALYITEFFDNGHGDCLLDPPEMTIPLAAELPGHT----FGLDQQCQQAFGNKYTHCSNAPADQTCVQLWC------REEGKIQCTTRNGSLHWADGTPCGEDRRCREGLCLSS----------------------------AMEEAGEQKVPVNGGWGEWGPWGPCSRTCGGGVEFSHRECTS------PVPQNGGLYCVGQRVKYQSCNTQTCPEDHGKSFREEQCEKYNSDRYMDIKGN-IKQWIPKYSGVSPRDRCKLVCRAKGSNEFKVFEAKVVDGTTCGPDTTSICVQGQCIKAGCDQVIGSNEKLDKCSVCGGDGTTCRKISGSLNKATIGYIDIVTIPAGATNIDIKQRSHRGIPHDGNYLAVKAQDGTYILN---GNFSVSMAEQDVPVPGAMLRYSGSSTTLERLLSFHRLQEPITIQLLSTAGDISPPR-------IKYTFFLPRDVPFSKPGTES---RISTHVISPFGGFDWVLGEWSECSKSCGAGWSRRSVECRD---GEGSLSYLCDADLRPADIRPCGDLPCPMWQMG--PWSACSRTCGPGERHRTVVCLDYAGKVLEPQKCNPDKRPEVAVGDCFYQDC------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9W1Z6-1", "uniprot_id": "Q9W1Z6_DROME", "id": "Q9W1Z6-1", "name": "", "aln": "-MTVAAIGSNRHRRLALIVLTTLWLLIGASSSSSSTSSTNPKSVNIELRRKRSLHYNGIELDKNTLVGHLREHERALIFGSRSPEEAPEFKLVHLAQQRPEEQQRLEERKRPGEAEQHGGNPHQRRQRRSLPSEDGNGPLPPEEEEQEAGEDVEARLQLQQSPQLIDDAFIFIRRTENGTQFVEHSPQLLKRLERCFYRSPAAALDLCEPGNVRGVFQQNGSDLVIHPLPARFGTGTHVLYQARVDKSGGGYSEASSRRTASPLDSQLQFEPDAEEFNEPRRRLRAQSQLQSPLRLRFQPRHHHPHQHHQQRRRRYIGDAPRSRWSDIPEELFIETAIFVDSDLYAHMQKNFPTNTESKVVSFLLAMINGVQLLYHHPTLGRRINFVLKRLEIWKSWDPPGLVRSRDVENYLNSFCKWQEKLNPFSDADPLHYDHALVLTGLDLVTYDKGKANSQVVGMATVKGMCTSIYSCTINEAKHFESVFVVAHEIGHNLGMRHDAKEISCDPT-----MHIMSPKLGSG--KVTWSKCSRTYLEDFLMDPQAECLFDRDSFAGPWDHTAGGRLPGERFNANQQCMLRFGKNFMQASTQSKMEICRDLHCRQDGLPWTSHPALEGTECGPNMWCRGGTCEARSSKQGSYSALKSWPPEHIPEATHEKIIRHEPNRIPPLLHDYNPMDNELPGSPSNWGEWSEPSACESGCLYGQSRRLLEGSTGLRTLNRSCLNFPSRCIGRDRRFVTCNTPQCHKVPVQTINDFATQVCMQARKSDPELTGEGQQLPSTLDASCKIFCRTRTNGTKSRRWTFPDGTTCKAKQHNPEDITYCISGRCERFSCDNSTSNFFKMDSSFCEARSVRPTRDSSDQESRQQTNRQRYAERQEGKPQKNHYENEVAKRPSYGQGNHINAPASPYKRRNYHKPYPPEIPRPPPPASASLIALDRSSSSESEWVAHPGCHSNCMTDSKGVQGVTSRLTGVESIQLCSYRIQPCERLQTAAEYAEQTCARYRQKVRGLSGHGAQISASIDEPDRSCRVGCQDEFIKYRYYLVNGRNGHFPPGTRCSPVGKRYCVYGRCLEFGDDDLPLDKTHISLGQLRTRRKRSSISNDLFNITEIFIKPSHSDISAENIEFTQPIHVSADELSSKSR", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : *: * . : .. : . . : : * :.. :* ::: :: . .* * . : . * .. .*:. * * * : *:* :* . :.: . . * . . :: : . . *:: :. ::* :..*:.: . :: .:*::: . :: **:: . :.::: :: : :. * * : *..** **. :* *: .* *** *:::* :: .:.:*:* : :* . **:: : : :::...::**:** *.* ** .: . * *:* : .:.** ** *: ::: . :.:**:* . * *: : :*** ** .: :... . : * :* . *. *. *. * .* . . : . ..*. * . *. * * . * * *:*. :: :*:* * :::.: : . * . . * :*. ..* : *: .. .:.. : .. ... .*: : *: *:* : .**: .. *:*.. . . . *. *.. . . . * .: : :.. *. ::: . * . . . . .::: . * :: .. :. . : . * * : . ::. * :: : .. .* :* . . . :: * . . * . : * * ", "identical_positions": 114, "similar_positions": 266, "identity": "9.97%" }, { "cls_id": "homologset.agr.MGI:1353470", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P70271-1", "uniprot_id": "PDLI4_MOUSE", "id": "P70271-1", "name": "PDZ and LIM domain protein 4", "aln": "--------------------------------------MTHSVTLRGPSPWGFRLVGGRDFSAPLTISRVHAGSKAALAALCPGDLIQAINGESTELMTHLEAQNRIKGCHDHLTLSVSRPENKN------------------WPSAPDD-KAQAHRIHID--------------PESQDCSPATSRR--SSVSGISLEDNRSGLGSPYGQ---------------PPRLPVPHNGSSNEATLPAQMSALHVSPPTSADTARVLPRNRDCRVDLGSEVYRMLREPAEPTASEPKQSGSFRYLQGMLEAGEGGDRPGSGGPRNLKPAASKLGAPLSGLQGLPECTRCGHGIVGTIVKARDKLYHPECFMCSDCG--------------------------------LNLKQRGYFFLDERLYCENHAKARVKPPEGYDVVAVYPNAKVELV--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P50479-1", "uniprot_id": "PDLI4_HUMAN", "id": "P50479-1", "name": "PDZ and LIM domain protein 4", "aln": "--------------------------------------MPHSVTLRGPSPWGFRLVGGRDFSAPLTISRVHAGSKAALAALCPGDLIQAINGESTELMTHLEAQNRIKGCHDHLTLSVSRPEGRS------------------WPSAPDDSKAQAHRIHID--------------PEIQDGSPTTSRR--PSGTGTGPEDGRPSLGSPYGQ---------------PPRFPVPHNGSS-EATLPAQMSTLHVSPPPSADPARGLPRSRDCRVDLGSEVYRMLREPAEPVAAEPKQSGSFRYLQGMLEAGEGGDWPGPGGPRNLKPTASKLGAPLSGLQGLPECTRCGHGIVGTIVKARDKLYHPECFMCSDCG--------------------------------LNLKQRGYFFLDERLYCESHAKARVKPPEGYDVVAVYPNAKVELV--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P36202-1", "uniprot_id": "PDLI4_RAT", "id": "P36202-1", "name": "PDZ and LIM domain protein 4", "aln": "--------------------------------------MTHAVTLRGPSPWGFRLVGGRDFSAPLTISRVHAGSKAALAALCPGDSIQAINGESTELMTHLEAQNRIKGCHDHLTLSVSRPENKN------------------WPSSPND-KAQAHRIHID--------------PEAQDGSPATSRR--SSISGISLEDNRSGLGSPYGQ---------------PPRLPVPHNGSSNEVTLPSQMSALHVSPPPSADTPRILPRNRDCRVDLGSEVYRMLREPAEPAASEPKQSGSFRYLQGMLEAGEGGDRPGSGGSRNLKPAASKLGAPLSGLQGLPECTRCGHGIVGTIVKARDKLYHPECFMCSDCG--------------------------------LNLKQRGYFFLDERLYCENHAKARVKPPEGYDVVAVYPNAKVELV--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "B7YZE5-1", "uniprot_id": "B7YZE5_DROME", "id": "B7YZE5-1", "name": "PDZ domain-containing protein", "aln": "MPEQLGLLWSVPESKSKAPIIKVSCGIGDTDGYPAFDVDSDAYATKDDSRWGFLITGGAEFHMPLTVFQVTPNGLADKAGIRLGDIILEINEEDASQLTLSQAHEKINSTPKKIHFLLRNMEEDDPMGQFEAGEEKSIVMRVPKPLPPPSGRIRASSIEMRLLEMQRKLSAIAEIPKILCSTLATVSQNFGRMSESEVDEDDVGEEEAYVQRKFSYDEDALDFELRNGEQAGDTDSDEEDLVLVREEDAEDVDVPKGAKQSKLLKDVTPESDYASEANYPANEASDDTESDDEDEPGSTVYFMKLPAAAAEDTYSSTEDEDDSDFLNTTYTWNLRNVPKLRINDAEAEGELTLGHQAREVPQQEQPQEKQPCLEPEPPKVRPATPTPKAPPQESAEGQTQKLLFRLDKLERSWPWADREKIIYKQSTCHLVPRKPLGLVGQRMQLLLKDKKE", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ..: : :. * *** :.** :* ***: :* ... * *.: ** * ** *.:. :* :*:::*:. .:: : : . * . * .* . : :* *.: *: : :* : : ::. . ..* * . . :... : .* : .: .*. * .*. .: * .. * . . :. : : .:.** *: : *. . ... . : . :. * .: * ..* : :**: : : . * *: :*.: : *.. .::..:: * : .:*. : :: ", "identical_positions": 52, "similar_positions": 121, "identity": "11.5%" }, { "cls_id": "homologset.agr.MGI:1353472", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P62425-1", "uniprot_id": "RL7A_RAT", "id": "P62425-1", "name": "Large ribosomal subunit protein eL8", "aln": "----MPK-GKKAKGKKVAPAPAVVKKQEAKKVVNPLFEKRPKNFGIGQDIQPKRDLTRFVKWPRYIRLQRQRAILYKRLKVPPAINQFTQALDRQTATQLLKLAHKYRPETKQEKKQRLLARAEKKAAGKGDV-PTKRPPVLRAGVNTVTTLVENKKAQLVVIAHDVDPIELVVFLPALCRKMGVPYCIIKGKARLGRLVHRKTCTTVAFTQVNSEDKGALAKLVEAIRTNYNDRYDEIRRHWGGNVLGPKSVARIAKLEKAKAKELATKLG", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P62424-1", "uniprot_id": "RL7A_HUMAN", "id": "P62424-1", "name": "Large ribosomal subunit protein eL8", "aln": "----MPK-GKKAKGKKVAPAPAVVKKQEAKKVVNPLFEKRPKNFGIGQDIQPKRDLTRFVKWPRYIRLQRQRAILYKRLKVPPAINQFTQALDRQTATQLLKLAHKYRPETKQEKKQRLLARAEKKAAGKGDV-PTKRPPVLRAGVNTVTTLVENKKAQLVVIAHDVDPIELVVFLPALCRKMGVPYCIIKGKARLGRLVHRKTCTTVAFTQVNSEDKGALAKLVEAIRTNYNDRYDEIRRHWGGNVLGPKSVARIAKLEKAKAKELATKLG", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P12970-1", "uniprot_id": "RL7A_MOUSE", "id": "P12970-1", "name": "Large ribosomal subunit protein eL8", "aln": "----MPK-GKKAKGKKVAPAPAVVKKQEAKKVVNPLFEKRPKNFGIGQDIQPKRDLTRFVKWPRYIRLQRQRAILYKRLKVPPAINQFTQALDRQTATQLLKLAHKYRPETKQEKKQRLLARAEKKAAGKGDV-PTKRPPVLRAGVNTVTTLVENKKAQLVVIAHDVDPIELVVFLPALCRKMGVPYCIIKGKARLGHLVHRKTCTTVAFTQVNSEDKGALAKLVEAIRTNYNDRYDEIRRHWGGNVLGPKSVARIAKLEKAKAKELATKLG", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P46223-1", "uniprot_id": "RL7A_DROME", "id": "P46223-1", "name": "Large ribosomal subunit protein eL8", "aln": "MVVKKPRPKKKPVTKKVAPAPLAVKKPVVKKVVNQLFEKRPKNFGIGQNVQPKRDLSRFVRWPKYIRVQRQKAVLQKRLKVPPPIHQFSQTLDKTTAVKLFKLLEKYRPESPLAKKLRLKKIAEAKAKGKDVE-PKKKPSYVSAGTNTVTKLIEQKKAQLVVIAHDVDPLELVLFLPALCRKMGVPYCIVKGKARLGRLVRRKTCTTLALTTVDNNDKANFGKVLEAVKTNFNERHEEIRRHWGGGILGSKSLARISKLERAKARELAQKQG", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P29453-1", "uniprot_id": "RL8B_YEAST", "id": "P29453-1", "name": "Large ribosomal subunit protein eL8B", "aln": "----------MAPGKKVAPAPFGAKSTKSNKAKNPLTHSTPKNFGIGQAVQPKRNLSRYVKWPEYVRLQRQKKILSIRLKVPPTIAQFQYTLDRNTAAETFKLFNKYRPETAAEKKERLTKEAAAIAEGKSKQDASPKPYAVKYGLNHVVSLIENKKAKLVLIANDVDPIELVVFLPALCKKMGVPYAIIKGKARLGTLVNQKTSAVAALTEVRAEDEAALAKLVSTIDANFADKYDEVKKHWGGGILGNKAQAKMDK--RAKTSDSA----", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P17076-1", "uniprot_id": "RL8A_YEAST", "id": "P17076-1", "name": "Large ribosomal subunit protein eL8A", "aln": "----------MAPGKKVAPAPFGAKSTKSNKTRNPLTHSTPKNFGIGQAVQPKRNLSRYVKWPEYVRVQRQKKILSIRLKVPPTIAQFQYTLDRNTAAETFKLFNKYRPETAAEKKERLTKEAAAVAEGKSKQDASPKPYAVKYGLNHVVALIENKKAKLVLIANDVDPIELVVFLPALCKKMGVPYAIVKGKARLGTLVNQKTSAVAALTEVRAEDEAALAKLVSTIDANFADKYDEVKKHWGGGILGNKAQAKMDK--RAKNSDSA----", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . ******* .*. :*. * * .. ******** :****:*:*:*:**.*:*:***: :* ******.* ** :**: **.: :** .*****: ** ** * * **. .. :* : * * *. *:*:***:**:**:****:***:******:******.*:******* **.:**.:. *:* * :*:. :.*::.:: :*: ::::*:::****.:** *: *:: * :** : * ", "identical_positions": 125, "similar_positions": 73, "identity": "45.96%" }, { "cls_id": "homologset.agr.MGI:1353474", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9VEX1-1", "uniprot_id": "Q9VEX1_DROME", "id": "Q9VEX1-1", "name": "", "aln": "MNQTQVNNFLKCFLQIDEPSNRWTSRHDGEDLDDNDHDHDHDDDNDDDESGVLVAKVTAMVVLFCASAICGSIPFLLNRCYRWTEN-QTNARSAIVVKCLLYFGGGVLLATTFLHLLPEVQEVVEELQECG----------IIGELTFPLAELLMCCGFFLMYFIEEAMHTYVHHHQKD---------------EAGAAFE----RGHSIRNSHLLKPTEGNATTPTAPPAPLAGTAELGTLSVQNLLQNDLEQQKFATKPQQQANGHGHSHGH--GHGHSHLPVIADDADAGDMLASSLRGLFIVSALSLHELFEGMAIGLESSASSVWFMFGAVSAHKLVLAFCVGVELIVA-RTRMLLAVLYVLTFAVVSPLGIGIGILINHG-EETSGPSLVSA-ILQGFACGTLIYVVFFEILSKN------RSGLRAYLALFVGFLVMFGLQQLTSIGGHGHSHSHSSCSTSEHTHNHQETETETRSASGHTHGHQHDHDHPHHHNHAEELATVHNYEQQLQLLRQVTQKLLEAHPKKDA", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "A1Z6P0-1", "uniprot_id": "A1Z6P0_DROME", "id": "A1Z6P0-1", "name": "", "aln": "--------------MVDQH--------------------------------LIVAKIVAIVVLFLVTLIFCFIPYLLDRFYKWTQRPENNAREFKVVLCLLNFGGGVLIATTFIHMLPEVVEVVNALQDCR----------MLAPTPFGLPEVLLCTGFYLMYCIEETMHFVVRRRQQRK------------LREVVTIKD----AGEELRTEIVVQPEE----SPKEP--------------------------------------------------------------------NWLRGLGIIVALSLHELFGGMAIGLEMSVSTVWFMTGAISVHKLVLAFCIGMEIMMA-HTRWLLAVVYLLVFSIVTPIGVGIGIAVSES-AAANQPSTVSG-ILQGLACGTLIYVVFFEIVAKN------HAGIRILLSSMVGFVLMFGLQ--IAIG-EAKGKSHFTCP----------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9NY26-1", "uniprot_id": "S39A1_HUMAN", "id": "Q9NY26-1", "name": "Zinc transporter ZIP1", "aln": "-----MGPWGEPELLVWRP---------------------EAVASEPPVPVGLEVKLGALVLLLVLTLLCSLVPICVLRRP--GANHEGSASRQKALSLVSCFAGGVFLATCLLDLLPDYLAAIDEALAA-----------LHVTLQFPLQEFILAMGFFLVLVMEQITLAYKEQSGPSP------------LEETRALLG-TVNGGPQHWHDGPGVPQASG-----APATP-----------------------------------------------------------------SALRACVLVFSLALHSVFEGLAVGLQRDRARAMELCLALLLHKGILAVSLSLRLLQS-HLRAQVVAGCGILFSCMTPLGIGLGAALAES-AGPLH-QLAQS-VLEGMAAGTFLYITFLEILPQE------LASSEQRILKVILLLAGFALLTGLLFIQI--------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9QZ03-1", "uniprot_id": "S39A1_MOUSE", "id": "Q9QZ03-1", "name": "Zinc transporter ZIP1", "aln": "-----MGPWGEPELLVWRP---------------------EAVASEPSVPVGLEVKLGALVLLLLLTLICSLVPVCVLRRS--GANHEASASGQKALSLVSCFAGGVFLATCLLDLLPDYLAAIDEALEA-----------LHVTLQFPLQEFILAMGFFLVLVMEQITLAYKEQTSPPH------------PEETRALLG-TVNGGPQHWHDGPGIPQAGG-----TPAAP-----------------------------------------------------------------SALRACVLVFSLALHSVFEGLAVGLQRDRARAMELCLALLLHKGILAVSLSLRLLQS-HLRVQVVAGCGILFSCMTPLGIGLGAALAES-AGPLH-QLAQS-VLEGMAAGTFLYITFLEILPQE------LATSEQRILKVILLLAGFALLTGLLFVQI--------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P59889-1", "uniprot_id": "S39A1_DANRE", "id": "P59889-1", "name": "Zinc transporter ZIP1", "aln": "------------------------------------------------MDYLLQVKVGALVGLLLLTLFFGFIPARMKWFH--VTG--GTELHKAVLSFVSCFAGGVFLSACLLDIIPDYLSDIHGELQK-----------RDLDDGFPLPEFIMACGFFTVLILEKMVLSCTEGHRN---------------EETAPLLAPAAPNGHAHGHPSVNDLEGSGHHVHVDFHAH-----------------------------------------------------------------SSFRSFMLFLSLSLHSVFEGLAIGLQTTNAKVLEICIAILVHKSIIVFSLSVKLVQS-AVKPLWVVLYVTVFAIMSPLGIGIGIVVIET-ERQAG-GLIQA-VLEGLAAGTFIYITFLEILPHE------LNSSERPLLKVLFLLCGFSIMAALCFLG---------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0AC58HHL9-1", "uniprot_id": "A0AC58HHL9_DANRE", "id": "A0AC58HHL9-1", "name": "", "aln": "----------------------------------------MTIMMMMDSSAALHLNLLTLTVMFCFSLLCGFSPGFFMRQAARYTS--DPGSRLRALSLASCLSSGVFLGFSLLDLLPKYLTDMRDTFSR-----------LDITLRFPLSEFLLAMGVLLVLLVEQMLLAFREQVCVSS------------VEKQTLIER-----TRLYVEDSRTH--------------------------------------------------------------------------------EALRVCLLLLCVCVRSLLEGVCA-----VPPPLWSCGAALLREGLLAFGLALQLAPA-GLRRAVATGGLVLFCSARPVAMGTAMLRGTPGDQAYTADVVRC-AVEGLTCGIFICISISGLLFPE------SSSPKQRMHKVAFLLTGFALVTAVLISQV--------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VFA2-1", "uniprot_id": "Q9VFA2_DROME", "id": "Q9VFA2-1", "name": "", "aln": "-----MSLPTDGLNMEITP-----------------------SPTLAATSRGDLEKVLAMLVLGLGSLLFGLLPAFISERN--------RRRFPLTASLLLCFGAGILLATALVHILPEVREQMDSKFAEV----------AMCGGFFIIYFIDEFIHYFFGEAIQHTHAHDAETPATEPPRRPTNDNGYGAVDERAPLLSAEPNTSHGHSHHHSHDHDHNHPASASGCNDASVEDAN---------------------------------------------ARICHTSHTEPCAQSMTGTLGLFVALSLHSAIEGLAIGVQNSSTKVLFLLGAVACHKFVMGFCLGLEFRSNPQTSFRAQFVGISVFALGAVIGIGLGMLIVDV--PAAWSSKTLP-IVQALAGGTLFYVTVCEVIPREKARW--HSNSTRRWAGFAQFATVLAGFATMCIINFYLSDED--------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q12436-1", "uniprot_id": "ZRT2_YEAST", "id": "Q12436-1", "name": "Low-affinity zinc transporter ZRT2", "aln": "---------MVDLIARDDS--------------------VDTCQASNGYNGHAGLRILAVFIILISSGLGVYFPILSSRYS-------FIRLPNWCFFIAKFFGSGVIVATAFVHLLQPAAEALGDECLGGTFAEYPWAFGICLMSLFLLFFTEIITHYFVAKTLGHDHGDHGEVTSIDVDAPSSGFVIRNMDSDPVSFNNEAAYSIHNDKTPYTTRNEEIVATPIKEKEPGSNVTNYDLEPGKTESLANELVPTSSHATNLASVPGKDHYSHENDHQDVSQLATRIEEEDKEQYLNQILAVFILEFGIIFHSVFVGLSLSVAGEEFETLFIVLTFHQMFEGLGLGTRVAETNWPESKKYMPWLMGLAFTLTSPIAVAVGIGVRHSWIPGSRRALIANGVFDSISSGILIYTGLVELMAHEFLYSNQFKGPDGLKKMLSAYLIMCCGAALMALLGKWA------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .: :: : : : * :..*:::. ::.:: : * : : . . . . : : .:. : *:. : : . : * :.:. . .:.:: * :: . :: : . : ", "identical_positions": 6, "similar_positions": 56, "identity": "1.12%" }, { "cls_id": "homologset.agr.MGI:1353479", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9VNX2-1", "uniprot_id": "Q9VNX2_DROME", "id": "Q9VNX2-1", "name": "", "aln": "-----------MAASEAPPADPAVEVAPPAKDSEDVTLDAILKHLGQFGRFQLIIFLLICLPMMFHAMFSVTYVFTAATVTHRCSVEECD-LPGSNYYEPHTNWSIP-----KNGKDLDSCNRYTN------SELPQWN-HSVDICSADHFTKNKEACAHNEFVFRDD--EVTISNDFGIFC-DDEWKLSMVGTINNLGQFFGIPIGGFVADRYGRSFSIALGGILGAVLGVIRSFSPSYGWFLVFEFLDNMTSSTLYSTCFVIGIELVGPKR-RVLACSVITVFYAVGEVLLAMSAKAFHDWRILLRITYGPSLILLAYFWILPESVRWLLSQGKEERAKNILRRAAHVNKRELPESVLDKLVLANRDKLQ-QSSESR--------FPIREAFKNFK------WRIANCSLCWIVHVLVYYGLSLNVVLLDGDKYNNFAYIALVEIPGFFMPLLIMDRFGRRYSLCGLMLASGLCCIGTIFTGADQ-------------------PVLQLVLFLVGKLTITASFQVLYFFASEIYPTNLRNSLLSFCSMMGRFGSMLAPQTPLLAKYYANAPAMLFAGAAIVSGLLTLFFPETTNVVLPTTVQEADAIGVKKQSKSKDLDLV-----------------VTATQAQ--------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VNW8-1", "uniprot_id": "Q9VNW8_DROME", "id": "Q9VNW8-1", "name": "Major facilitator superfamily (MFS) profile domain-containing protein", "aln": "MTSQKEGNGYRRSDSKTTGHADAEAATQTAGGDEDNSLDAILVRIGQFGRYQIINYVLLCVPMLFNAFFSISYVFTASTVVHRCTVPQCD-SPSSVYEEDWLGFTIP-----KKNSAWDDCHRYAAN---ISDAISGYTDPSGQYCLKEYFTITSETCGR-DFKFRDE--EKTISTEFGIYC-EDEWKLSMVGTINNVGQFVGIPLGGYFADRYGRRTMLAVAGSVSALMGVIRSLSSNYSMFLVFEFLDMAVGSTLFPTAFLLAIELVGPKR-RVAAATIITIFYALGEAFLGFLASQVQHWRWLLRVLYAPAVLQILFLWILPESVRWLLSQGAEEKASNVLRRAARINQRPLPEEQLNDLLTSNRQKLS-QANESQ--------YPIMRAVVFFS------LRIANCCLCWFTHTLIALGLSLNSVNLGGNKYTNFMLNGFIQIPGLLLPLVIMDRVGRRHSLCASMLLCAICMGASAAVPADN-------------------YAGSLALFLIGKLAITCSFQILYFFTSEIFPTNVRNTLLSLCSMVGRIGSMLAPQTPLLAKYYIYAPQILFATFALISGFLTLAFPETADKVLPTTIEEARDLNQAKRRSERSP-----------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "A0A0B4KFK6-1", "uniprot_id": "A0A0B4KFK6_DROME", "id": "A0A0B4KFK6-1", "name": "Major facilitator superfamily (MFS) profile domain-containing protein", "aln": "-----------------------MSAPAAGAASAVLDFDDILVEIGEFGRFQRRNYLLICLPVLFAAANSLSYVFTAGSPTYRCYVPECDKLVDAEYGANWVSIAVPGSWSKRGHFTPSTCERFVANGDHLESSSDPWSAWPLDQCFAENFTTETERCNQ--FVYGSS--ERTIVQQWGLQCPENLWKLAFVGTIHFAGLVVGTALSGYLADRYGRKHIFLFCIVFMALTGVAQALSWDYISFLFFALLNAVGTSGVYPLAFIIGVEMVGPRK-REMSSIVLNYFYAVGEALLG-LSVFLPDWRQLQLALSVPPLICVAYFWLVPESVRWLLARNRREQAGVIIRRAAKVNRRDISVELMASFKQQELDAETGQEDDVEGGLHVKKDDKIWLAVKEVARSHILMGRYAILLLIWAVNAIVYYGLSLNATSLSGNKYLNFALVCLVEIPGYSLAWLFLRRFGRRVALSGSLLLCSITCVASGFVTLAQGDWIPCQTGVESRHSWSCANWLVVTLFLVGKLGITSSFAVIYTFTAEMMPTVIRSGGVGVMSTFARFGAMLAPFVPLLASYYDPLPLLLFGTLSLVAGLLSLLLPETFNRKLPDTVEEAIALGK--------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VCA2-1", "uniprot_id": "ORCT_DROME", "id": "Q9VCA2-1", "name": "Organic cation transporter protein", "aln": "-----------------------------------MGYDDVITHLGEFGPYQKRIYYLLCLPAIVCAFHKLAGVFLLAKPDFRCALPYEN-GSIYELSPHLWNLSYPEN---------ERCSYYDVD------YTEEYLNG------SIPRSSNETKTCSS-YVYDRSKYLNSAVTEWNLVC-SRSLLSATSDSLFMLGVLLGSLIFGQMSDKLGRKPTFFASLVLQLIFGVLAAVAPEYFSYTISRMIVGATTSGVFLVAYVIALEMVGSSY-RLFAGVAMQMFFSVGFMLTAGFAYFIHDWRWLQIAITLPGLLFLCYYWIIPESARWLLMKGRKDEAFVIIEKAAKENKVEVPNEIYEQLVD------EVAEKKKQDEMAASQPAATVFDLLRYPN---LRRKTLLIFFDWFVNSGVYYGLSWNTNNLGGNQLVNFMISGAVEIPGYTLLLFTLNRWGRRSILCGTMMVAGISLLATIFVPSDMN-------------------WLIVACAMIGKLAITSSYGTIYIFSAEQFPTVVRNVGLGASSMVARVGGILAPYLKLLGEIWRPLPLIICGALSLTAGLLSLLLPETLNKPMPETIEDGENFGKKPAPQET-----AEEG------------GTQELSG--MLNGKSG", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q95R48-1", "uniprot_id": "OCTL_DROME", "id": "Q95R48-1", "name": "Organic cation transporter-like protein", "aln": "-----------------------------------MGYDEAIIHLGDFGRYQKIIYFLICLTSIPVAFHKLAGVFLLAKPDFRCALPFEN-GSSYDLPTHLWNLSYPEN---------ERCSYYDVD------YTEEYLNG------SIPRSSNETKTCSS-YVYDRSKYLNSAVTEWNLVC-GRDFMAATSDSLFMLGVLLGSIVFGQLSDKYGRKPILFASLVIQVLFGVLAGVAPEYFTYTFARLMVGATTSGVFLVAYVVAMEMVGPDK-RLYAGIFVMMFFSVGFMLTAVFAYFVHDWRWLQIALTLPGLIFMFYYWIIPESARWLLLKGRKDCAIANMQKAARFNKVEISDEALSELLDEGENSEEKAKQKLEDQELDEGPPPSVWDLFCYPN---LRRKTLLIFLDWLVTSGVYYGLSWNTSNLGGNVLLNFVISGAVEIPAYIFLLLTLNRWGRRSILCGCLVMAGLSLLATVIIPQRMH-------------------TLIVACAMLGKLAITASYGTVYIFSAEQFPTVVRNVALGAASMVARISGMMAPFLNFLATIWKPLPLLICGSLTLVAGLLSLLLPETHNKPMLETIADGERFGKKTKADVY-----LETGQELRAPEAQPLKGSGETNGSTIANGHK-", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9R141-1", "uniprot_id": "S22A4_RAT", "id": "Q9R141-1", "name": "Solute carrier family 22 member 4", "aln": "----------------------------------MRDYDEVIAFLGDWGPFQRLIFFLLSASIIPNGFNGMSVVFLAGTPEHRCLVPHTV-NLSSAWRNHSIPLETKDGR-----QVPQSCRRYRLA------TIANFSALGLEPGLDVDLEQLEQESCLDGWEYSKDVFLSTIVTEWNLVC-EDDWKTPLTTSLFFVGVLCGSFVSGQLSDRFGRKKVLFATMAVQTGFSFVQIFSTNWEMFTVLFAIVGMGQISNYVVAFILGTEILSKSVRILFSTLGVCTFFAIGYMVLPLFAYFIRDWRMLLLALTLPGLFCVPLWWFIPESPRWLISQRRFEEAEQIIQKAAKMNGIMAPAVIFDPLELQELNSLKQQK-------------VFILDLFKTRN---IATITVMSVMLWMLTSVGYFALSLNVPNLHGDVYLNCFLSGLIEVPAYFTAWLLLRTLPRRYIIAGVLFWGGGVLLLVQVVPEDYN-------------------FVSIGLVMLGKFGVTSAFSMLYVFTAELYPTLVRNMAVGITSMASRVGSIIAPYFVYLGAYNRLLPYILMGSLTVLIGIITLFFPESFGVTLPENLEQMQKVRGFRCGKKS-----TVSMD-------------REENPKVLITAF--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9Z306-1", "uniprot_id": "S22A4_MOUSE", "id": "Q9Z306-1", "name": "Solute carrier family 22 member 4", "aln": "----------------------------------MRDYDEVIAFLGEWGPFQRLIFFLLSASIIPNGFNGMSVVFLAGTPEHRCLVPDTV-NLSSSWRNHSIPLETKDGR-----QVPQSCRRYRLA------TIANFSAMGLEPGQDVDLEQLEQESCLDGWEYDKDIFLSTIVTEWNLVC-EDDWKTPLTTSLFFVGVLCGSFVSGQLSDRFGRKKVLFATMAVQTGFSFVQIFSTNWEMFTVLFAIVGMGQISNYVVAFILGTEILSKSVRIIFSTLGVCTFFAIGYMVLPLFAYFIRDWRMLLLALTLPGLFCVPLWWFIPESPRWLISQRRFAEAEQIIQKAAKMNSIVAPAGIFDPLELQELNSLKQQK-------------VIILDLFRTRN---IATITVMAVMLWMLTSVGYFALSLNVPNLHGDVYLNCFLSGLIEVPAYFTAWLLLRTLPRRYIIAGVLFWGGGVLLLIQVVPEDYN-------------------FVSIGLVMLGKFGITSAFSMLYVFTAELYPTLVRNMAVGITSMASRVGSIIAPYFVYLGAYNRLLPYILMGSLTVLIGIITLFFPESFGVTLPENLEQMQKVRGFRCGKKS-----TVSVD-------------REESPKVLITAF--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9H015-1", "uniprot_id": "S22A4_HUMAN", "id": "Q9H015-1", "name": "Solute carrier family 22 member 4", "aln": "----------------------------------MRDYDEVIAFLGEWGPFQRLIFFLLSASIIPNGFNGMSVVFLAGTPEHRCRVPDAA-NLSSAWRNNSVPLRLRDGR-----EVPHSCSRYRLA------TIANFSALGLEPGRDVDLGQLEQESCLDGWEFSQDVYLSTVVTEWNLVC-EDNWKVPLTTSLFFVGVLLGSFVSGQLSDRFGRKNVLFATMAVQTGFSFLQIFSISWEMFTVLFVIVGMGQISNYVVAFILGTEILGKSVRIIFSTLGVCTFFAVGYMLLPLFAYFIRDWRMLLLALTVPGVLCVPLWWFIPESPRWLISQRRFREAEDIIQKAAKMNNIAVPAVIFD--SVEELNPLKQQK-------------AFILDLFRTRN---IAIMTIMSLLLWMLTSVGYFALSLDAPNLHGDAYLNCFLSALIEIPAYITAWLLLRTLPRRYIIAAVLFWGGGVLLFIQLVPVDYY-------------------FLSIGLVMLGKFGITSAFSMLYVFTAELYPTLVRNMAVGVTSTASRVGSIIAPYFVYLGAYNRMLPYIVMGSLTVLIGILTLFFPESLGMTLPETLEQMQKVKWFRSGKKT-----RDSME-------------TEENPKVLITAF--", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * : :*::* :* : *:. . : . :: ** .. .** : * : : : : . : ::.: * . :: * . * : * .:*: ** : . .. .: .: : . : : .:::. *::. : : *:::* . : . .** * * :: : *::*** ***: : * :.:**: * . . : * .** : * *: * :::*. . : ** :.. :. . : ::**: :*.:: :* *::* ** :*. :. * .*...::** *. * :: . :: *:::* :**: . : .: : . ", "identical_positions": 63, "similar_positions": 131, "identity": "9.62%" }, { "cls_id": "homologset.agr.MGI:1353494", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P07943-1", "uniprot_id": "ALDR_RAT", "id": "P07943-1", "name": "Aldo-keto reductase family 1 member B1", "aln": "-----------------------------------MASHLELNNGTKMPTLGLGTWKSPPGQVTEAVKVAIDMGYRHIDCAQVYQNEKEVGVALQEKLKEQVVKRQDLFIVSKLWCTFHDQSMVKGACQKTLSDLQLDYLDLYLIHWPTGFKPGPD------YFPLDASGN--VIPSDTDFVDTWTAMEQLVDEGLVKAIGVSNFNPLQIERILNKPGLKYKPAVNQIECHPYLTQEKLIEYCHCKGIVVTAYSPLGSPDRPWAKPEDPSLLEDPRIKEIAAKYNKTTAQVLIRFPIQRNLVVIPKSVTPARIAENFKVFDFELSNEDMATLLSYNRNWRVCALMSCAKHKDYPFHAEV-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0A8I6A068-1", "uniprot_id": "A0A8I6A068_RAT", "id": "A0A8I6A068-1", "name": "aldose reductase", "aln": "-----------------------------------MASYLELNSGTKMPTLGLGTWKSPPGQVTEAVKVAIDMGYRHIDCTRVFQNEKEVGVALQEKLKEQVVKRQDLFIVSKLWCTFHDQSMVKGACQKTLSDLQLDYLDLYLTHWPTGFKPGPD------YFPLDALGN--VIPSDTDFVDTWTAMEQLVDEGLVKAIGVSNFNPLQIERILNKPGLKYKPAVNQIECHPYLTQEKLIEYCHCKGIMVTAYSPLGSPDRPWAKPEDPSLLEDPRIKEIAAKYNKTTAQVLIWFPIQRNLVVIPKSVTPARIADNFKVFDFELSSEDMATLLSYNRNWRVCALMSCVKHKDYPFHAEV-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P45376-1", "uniprot_id": "ALDR_MOUSE", "id": "P45376-1", "name": "Aldo-keto reductase family 1 member B1", "aln": "-----------------------------------MASHLELNNGTKMPTLGLGTWKSPPGQVTEAVKVAIDLGYRHIDCAQVYQNEKEVGVALQEKLKEQVVKRQDLFIVSKLWCTFHDKSMVKGAFQKTLSDLQLDYLDLYLIHWPTGFKPGPD------YFPLDASGN--VIPSDTDFVDTWTAMEQLVDEGLVKTIGVSNFNPLQIERILNKPGLKYKPAVNQIECHPYLTQEKLIEYCHSKGIVVTAYSPLGSPDRPWAKPEDPSLLEDPRIKAIAAKYNKTTAQVLIRFPIQRNLVVIPKSVTPVRIAENLKVFDFEVSSEDMATLLSYNRNWRVCALMSCAKHKDYPFHAEV-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P15121-1", "uniprot_id": "ALDR_HUMAN", "id": "P15121-1", "name": "Aldo-keto reductase family 1 member B1", "aln": "-----------------------------------MASRLLLNNGAKMPILGLGTWKSPPGQVTEAVKVAIDVGYRHIDCAHVYQNENEVGVAIQEKLREQVVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTGFKPGKE------FFPLDESGN--VVPSDTNILDTWAAMEELVDEGLVKAIGISNFNHLQVEMILNKPGLKYKPAVNQIECHPYLTQEKLIQYCQSKGIVVTAYSPLGSPDRPWAKPEDPSLLEDPRIKAIAAKHNKTTAQVLIRFPMQRNLVVIPKSVTPERIAENFKVFDFELSSQDMTTLLSYNRNWRVCALLSCTSHKDYPFHEEF-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "M9PF61-1", "uniprot_id": "ALDR_DROME", "id": "M9PF61-1", "name": "Aldo-keto reductase 1B", "aln": "MNTLMKIQLVRPVFRITLRNYGKPERFMWCQKEYARAPKVVCLDGNEIPVIGLGTFNSPKGQVTEAVKVAIDAGYRHIDCAYVYQNEDEVGDGVEAKIKEGVVKREDLFITSKLWNTFHRPDLVKSALENTLSSLKLKYLDLYLIHWPMGYKEGCD------LFPTDKDGK--TLYSPVDYVDTWKAMEKLVEEGLVKSIGVSNFNRRQIERVLEVATIP--PVTNQIECHPYLTQKKLIDFCKSKDITITAYSPLGSPNRPWAKAGDPVILEEAKIKEIAAKKKKTPGQILIRYQVQRANIVIPKSVTKDRIESNFQVFDFELTPEEIEIIESFECNGRLVPLLNQYGHPHHPFEKDEY", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q12458-1", "uniprot_id": "YPR1_YEAST", "id": "Q12458-1", "name": "Aldehyde reductase YPR1", "aln": "-------------MPATLKN---------------SSATLKLNTGASIPVLGFGTWRSVDNNGYHSVIAALKAGYRHIDAAAIYLNEEEVG----RAIKDSGVPREEIFITTKLWGTEQRD--PEAALNKSLKRLGLDYVDLYLMHWPVPLKTDRVTDGNVLCIPTLEDGTVDIDTKEWNFIKTWELMQELPKTGKTKAVGVSNFSINNIKELLESPNNKVVPATNQIEIHPLLPQDELIAFCKEKGIVVEAYSPFGSANAP--------LLKEQAIIDMAKKHGVEPAQLIISWSIQRGYVVLAKSVNPERIVSNFKIFT--LPEDDFKTISNLSKVHGTKRVVDMKWGSFPIFQ----", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P14065-1", "uniprot_id": "GCY1_YEAST", "id": "P14065-1", "name": "Glycerol 2-dehydrogenase (NADP(+))", "aln": "-------------MPATLHD---------------STKILSLNTGAQIPQIGLGTWQSKENDAYKAVLTALKDGYRHIDTAAIYRNEDQVG----QAIKDSGVPREEIFVTTKLWCTQHHE--PEVALDQSLKRLGLDYVDLYLMHWPARLDPAYIKNEDILSVPTKKDGSRAVDITNWNFIKTWELMQELPKTGKTKAVGVSNFSINNLKDLLASQGNKLTPAANQVEIHPLLPQDELINFCKSKGIVVEAYSPLGSTDAP--------LLKEPVILEIAKKNNVQPGHVVISWHVQRGYVVLPKSVNPDRIKTNRKIFT--LSTEDFEAINNISKEKGEKRVVHPNWSPFEVFK----", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : * .:* :*:**:.* .: .:* .*:. ****** : :: **.:** ::: * *:::*:.:*** * : : * :::*. * *.*:**** *** . .* *. . : :.** *::* . * .*::*:***. ::: :* *..**:* ** *.*.:** :*: *.* : ****:**.: * :*:: * :* * ..:::* : :** :*:.***. ** * ::* :. ::: : . . :: *. ", "identical_positions": 86, "similar_positions": 97, "identity": "23.89%" }, { "cls_id": "homologset.agr.MGI:1353495", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P48962-1", "uniprot_id": "ADT1_MOUSE", "id": "P48962-1", "name": "ADP/ATP translocase 1", "aln": "-------------MGD--QALSFLKDFLAGGIAAAVSKTAVAPIERVKLLLQVQ-HASKQISAEKQYKGIIDCVVRIPKEQGFLSFWRGNLANVIRYFPTQALNFAFKDKYKQIFLGGVDRHKQFWRYFAGNLASGGAAGATSLCFVYPLDFARTRLAADVG--KGSSQREFNGLGDCLTKIFKSDGLKGLYQGFSVSVQGIIIYRAAYFGVYDTAKGMLPD-PKNVHIIVSWMIAQSVTAVAGLVSYPFDTVRRRMMMQSGRKGADIMYTGTLDCWRKIAKDEGANAFFKGAWSNVLRGMGGAFVLVLYDEIKKYV------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q05962-1", "uniprot_id": "ADT1_RAT", "id": "Q05962-1", "name": "ADP/ATP translocase 1", "aln": "-------------MGD--QALSFLKDFLAGGIAAAVSKTAVAPIERVKLLLQVQ-HASKQISAEKQYKGIIDCVVRIPKEQGFLSFWRGNLANVIRYFPTQALNFAFKDKYKQIFLGGVDRHKQFWRYFAGNLASGGAAGATSLCFVYPLDFARTRLAADVG--KGSSQREFNGLGDCLTKIFKSDGLKGLYQGFSVSVQGIIIYRAAYFGVYDTAKGMLPD-PKNVHIIVSWMIAQSVTAVAGLVSYPFDTVRRRMMMQSGRKGADIMYTGTVDCWRKIAKDEGRKAFFKGAWSNVLRGMGGAFVLVLYDEIKKYV------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P12235-1", "uniprot_id": "ADT1_HUMAN", "id": "P12235-1", "name": "ADP/ATP translocase 1", "aln": "-------------MGD--HAWSFLKDFLAGGVAAAVSKTAVAPIERVKLLLQVQ-HASKQISAEKQYKGIIDCVVRIPKEQGFLSFWRGNLANVIRYFPTQALNFAFKDKYKQLFLGGVDRHKQFWRYFAGNLASGGAAGATSLCFVYPLDFARTRLAADVG--KGAAQREFHGLGDCIIKIFKSDGLRGLYQGFNVSVQGIIIYRAAYFGVYDTAKGMLPD-PKNVHIFVSWMIAQSVTAVAGLVSYPFDTVRRRMMMQSGRKGADIMYTGTVDCWRKIAKDEGAKAFFKGAWSNVLRGMGGAFVLVLYDEIKKYV------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q26365-1", "uniprot_id": "ADT_DROME", "id": "Q26365-1", "name": "ADP/ATP translocase", "aln": "MGNISASITSQSKMGKDFDAVGFVKDFAAGGISAAVSKTAVAPIERVKLLLQVQ-HISKQISPDKQYKGMVDCFIRIPKEQGFSSFWRGNLANVIRYFPTQALNFAFKDKYKQVFLGGVDKNTQFWRYFAGNLASGGAAGATSLCFVYPLDFARTRLAADTG--KGG-QREFTGLGNCLTKIFKSDGIVGLYRGFGVSVQGIIIYRAAYFGFYDTARGMLPD-PKNTPIYISWAIAQVVTTVAGIVSYPFDTVRRRMMMQSGRKATEVIYKNTLHCWATIAKQEGTGAFFKGAFSNILRGTGGAFVLVLYDEIKKVL------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "O62526-1", "uniprot_id": "O62526_DROME", "id": "O62526-1", "name": "ADP/ATP translocase", "aln": "MGDEGG----GGGHGKG-DLKSFLMDFMMGGVSAAIAKTAVAPIERVKLILQVQ-EVSKQIAADQRYKGIVDCFIRIPKEQGFSSFWRGNLANVIRYFPTQALNFAFKDVYKSVFLGGVDKHKQFWRHFAGNLASGGAAGATSLCFVYPLDFARTRLAADVG--KGG-NREFNGLIDCLMKVIKSDGPIGLYRGFIVSVQGIVIYRAAYFGFYDTCRDFLPN-PKSTPFYVSWAIAQVVTTVAGIASYPFDTVRRRMMMQSGLKKSEMVYKNTAHCWLVIAKQEGIGAFFKGALSNIIRGTGGALVLALYDEMKKYF------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P18238-1", "uniprot_id": "ADT3_YEAST", "id": "P18238-1", "name": "ADP/ATP translocase 3", "aln": "MSSDAK-----------QQETNFAINFLMGGVSAAIAKTAASPIERVKILIQNQDEMIKQGTLDKKYSGIVDCFKRTAKQEGLISFWRGNTANVIRYFPTQALNFAFKDKIKLMFGFKKE--EGYGKWFAGNLASGGAAGALSLLFVYSLDFARTRLAADAKSSKKGGARQFNGLTDVYKKTLKSDGIAGLYRGFMPSVVGIVVYRGLYFGMFDSLKPLVLTGSLDGSFLASFLLGWVVTTGASTCSYPLDTVRRRMMMTSG---QAVKYNGAIDCLKKIVASEGVGSLFKGCGANILRSVAGAGVISMYDQLQMILFGKKFK", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P18239-1", "uniprot_id": "ADT2_YEAST", "id": "P18239-1", "name": "ADP/ATP translocase 2", "aln": "MSSNAQVKTPLPPAPAPKKESNFLIDFLMGGVSAAVAKTAASPIERVKLLIQNQDEMLKQGTLDRKYAGILDCFKRTATQEGVISFWRGNTANVIRYFPTQALNFAFKDKIKAMFGFKKE--EGYAKWFAGNLASGGAAGALSLLFVYSLDYARTRLAADSKSSKKGGARQFNGLIDVYKKTLKSDGVAGLYRGFLPSVVGIVVYRGLYFGMYDSLKPLLLTGSLEGSFLASFLLGWVVTTGASTCSYPLDTVRRRMMMTSG---QAVKYDGAFDCLRKIVAAEGVGSLFKGCGANILRGVAGAGVISMYDQLQMILFGKKFK", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P04710-1", "uniprot_id": "ADT1_YEAST", "id": "P04710-1", "name": "ADP/ATP translocase 1", "aln": "MSHTET----------QTQQSHFGVDFLMGGVSAAIAKTGAAPIERVKLLMQNQEEMLKQGSLDTRYKGILDCFKRTATHEGIVSFWRGNTANVLRYFPTQALNFAFKDKIKSLLSYDRER-DGYAKWFAGNLFSGGAAGGLSLLFVYSLDYARTRLAADARGSKSTSQRQFNGLLDVYKKTLKTDGLLGLYRGFVPSVLGIIVYRGLYFGLYDSFKPVLLTGALEGSFVASFLLGWVITMGASTASYPLDTVRRRMMMTSG---QTIKYDGALDCLRKIVQKEGAYSLFKGCGANIFRGVAAAGVISLYDQLQLIMFGKKFK", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . * :* **::**::**..:******:::* * . ** : : :* *::**. * ...:*. ****** ***:************** * :: : : : ***** ******. ** ***.**:******** * *:* ** : * :*:** ***:** ** **::**. ***.:*: : .: . . : *: :. :* *. ***:********* ** : * .: .* *. ** ::***. :*::*. ..* *: :**::: . ", "identical_positions": 129, "similar_positions": 76, "identity": "39.94%" }, { "cls_id": "homologset.agr.MGI:1353496", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P51881-1", "uniprot_id": "ADT2_MOUSE", "id": "P51881-1", "name": "ADP/ATP translocase 2", "aln": "---MTDAAVS---------------FAKDFLAGGVAAAISKTAVAPIERVKLLLQVQ-HASKQITADKQYKGIIDCVVRIPKEQGVLSFWRGNLANVIRYFPTQALNFAFKDKYKQIFLGGVDKRTQFWRYFAGNLASGGAAGATSLCFVYPLDFARTRLAADVGKAG--AEREFKGLGDCLVKIYKSDGIKGLYQGFNVSVQGIIIYRAAYFGIYDTAKGMLPD-PKNTHIFISWMIAQSVTAVAGLTSYPFDTVRRRMMMQSGRKGTDIMYTGTLDCWRKIARDEGSKAFFKGAWSNVLRGMGGAFVLVLYDEIKKYT------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q09073-1", "uniprot_id": "ADT2_RAT", "id": "Q09073-1", "name": "ADP/ATP translocase 2", "aln": "---MTDAAVS---------------FAKDFLAGGVAAAISKTAVAPIERVKLLLQVQ-HASKQITADKQYKGIIDCVVRIPKEQGVLSFWRGNLANVIRYFPTQALNFAFKDKYKQIFLGGVDKRTQFWRYFAGNLASGGAAGATSLCFVYPLDFARTRLAADVGKAG--AEREFKGLGDCLVKIYKSDGIKGLYQGFNVSVQGIIIYRAAYFGIYDTAKGMLPD-PKNTHIFISWMIAQSVTAVAGLTSYPFDTVRRRMMMQSGRKGTDIMYTGTLDCWRKIARDEGGKAFFKGAWSNVLRGMGGAFVLVLYDEIKKYT------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P05141-1", "uniprot_id": "ADT2_HUMAN", "id": "P05141-1", "name": "ADP/ATP translocase 2", "aln": "---MTDAAVS---------------FAKDFLAGGVAAAISKTAVAPIERVKLLLQVQ-HASKQITADKQYKGIIDCVVRIPKEQGVLSFWRGNLANVIRYFPTQALNFAFKDKYKQIFLGGVDKRTQFWLYFAGNLASGGAAGATSLCFVYPLDFARTRLAADVGKAG--AEREFRGLGDCLVKIYKSDGIKGLYQGFNVSVQGIIIYRAAYFGIYDTAKGMLPD-PKNTHIVISWMIAQTVTAVAGLTSYPFDTVRRRMMMQSGRKGTDIMYTGTLDCWRKIARDEGGKAFFKGAWSNVLRGMGGAFVLVLYDEIKKYT------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1NEI2-1", "uniprot_id": "A0A8M1NEI2_DANRE", "id": "A0A8M1NEI2-1", "name": "ADP/ATP translocase", "aln": "---MSDSVVS---------------FAKDFLAGGVAAAVSETAVAPIERVKLLLQVQ-HASKQITTDKQYKGIVDCVVRIPREQGFLSFWRGNLANVIRYFLTQALNFAFKDKYRRIFLDGVDQRTQFWRYFAGNLAAGGAAGATSLCLVYPLDFARTRLAADVGKTGT-AGREFKGLANCLVKIYRSDGVRGLYQGFNVSVQGIIIYRAAYFGIYDTAKGMLPD-PENTHIAVSWMIAHTVTIVAGFISYPFDTVRRSMMMQSGLKGADVMYSGSIDCWRKIARNEGPKAFFKGAWSNVLRSLGGSIVLVLYDEFKKVI------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q26365-1", "uniprot_id": "ADT_DROME", "id": "Q26365-1", "name": "ADP/ATP translocase", "aln": "MGNISASITSQSKMGKDF---DAVGFVKDFAAGGISAAVSKTAVAPIERVKLLLQVQ-HISKQISPDKQYKGMVDCFIRIPKEQGFSSFWRGNLANVIRYFPTQALNFAFKDKYKQVFLGGVDKNTQFWRYFAGNLASGGAAGATSLCFVYPLDFARTRLAADTGKGG---QREFTGLGNCLTKIFKSDGIVGLYRGFGVSVQGIIIYRAAYFGFYDTARGMLPD-PKNTPIYISWAIAQVVTTVAGIVSYPFDTVRRRMMMQSGRKATEVIYKNTLHCWATIAKQEGTGAFFKGAFSNILRGTGGAFVLVLYDEIKKVL------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "O62526-1", "uniprot_id": "O62526_DROME", "id": "O62526-1", "name": "ADP/ATP translocase", "aln": "---MGDEGGGGGHGKGD-----LKSFLMDFMMGGVSAAIAKTAVAPIERVKLILQVQ-EVSKQIAADQRYKGIVDCFIRIPKEQGFSSFWRGNLANVIRYFPTQALNFAFKDVYKSVFLGGVDKHKQFWRHFAGNLASGGAAGATSLCFVYPLDFARTRLAADVGKGG---NREFNGLIDCLMKVIKSDGPIGLYRGFIVSVQGIVIYRAAYFGFYDTCRDFLPN-PKSTPFYVSWAIAQVVTTVAGIASYPFDTVRRRMMMQSGLKKSEMVYKNTAHCWLVIAKQEGIGAFFKGALSNIIRGTGGALVLALYDEMKKYF------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P18238-1", "uniprot_id": "ADT3_YEAST", "id": "P18238-1", "name": "ADP/ATP translocase 3", "aln": "---MSSDAK-----------QQETNFAINFLMGGVSAAIAKTAASPIERVKILIQNQDEMIKQGTLDKKYSGIVDCFKRTAKQEGLISFWRGNTANVIRYFPTQALNFAFKDKIKLMFGFKKE--EGYGKWFAGNLASGGAAGALSLLFVYSLDFARTRLAADAKSSKKGGARQFNGLTDVYKKTLKSDGIAGLYRGFMPSVVGIVVYRGLYFGMFDSLKPLVLTGSLDGSFLASFLLGWVVTTGASTCSYPLDTVRRRMMMTSG---QAVKYNGAIDCLKKIVASEGVGSLFKGCGANILRSVAGAGVISMYDQLQMILFGKKFK", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P18239-1", "uniprot_id": "ADT2_YEAST", "id": "P18239-1", "name": "ADP/ATP translocase 2", "aln": "---MSSNAQVKTPLPPAPAPKKESNFLIDFLMGGVSAAVAKTAASPIERVKLLIQNQDEMLKQGTLDRKYAGILDCFKRTATQEGVISFWRGNTANVIRYFPTQALNFAFKDKIKAMFGFKKE--EGYAKWFAGNLASGGAAGALSLLFVYSLDYARTRLAADSKSSKKGGARQFNGLIDVYKKTLKSDGVAGLYRGFLPSVVGIVVYRGLYFGMYDSLKPLLLTGSLEGSFLASFLLGWVVTTGASTCSYPLDTVRRRMMMTSG---QAVKYDGAFDCLRKIVAAEGVGSLFKGCGANILRGVAGAGVISMYDQLQMILFGKKFK", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P04710-1", "uniprot_id": "ADT1_YEAST", "id": "P04710-1", "name": "ADP/ATP translocase 1", "aln": "---MSHTET----------QTQQSHFGVDFLMGGVSAAIAKTGAAPIERVKLLMQNQEEMLKQGSLDTRYKGILDCFKRTATHEGIVSFWRGNTANVLRYFPTQALNFAFKDKIKSLLSYDRER-DGYAKWFAGNLFSGGAAGGLSLLFVYSLDYARTRLAADARGSKSTSQRQFNGLLDVYKKTLKTDGLLGLYRGFVPSVLGIIVYRGLYFGLYDSFKPVLLTGALEGSFVASFLLGWVITMGASTASYPLDTVRRRMMMTSG---QTIKYDGALDCLRKIVQKEGAYSLFKGCGANIFRGVAAAGVISLYDQLQLIMFGKKFK", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : * :* **::**:::*..:******:::* * . ** : * :* *::**. * . .:*. ****** ***:*** ********** : :: : : ***** :*****. ** :**.**:******** *:* ** : * ::** ***:** ** **::**. ***::*: : .: . . : *: :. :* *. ***:***** *** ** : * .: .* *. ** ::***. :*::*. ..: *: :**::: ", "identical_positions": 121, "similar_positions": 77, "identity": "37.12%" }, { "cls_id": "homologset.agr.MGI:1353497", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O89035-1", "uniprot_id": "DIC_RAT", "id": "O89035-1", "name": "Mitochondrial dicarboxylate carrier", "aln": "--------------MAEARTSRWYFGGLASCGAACCTHPLDLLKVHLQTQQEV-KLRMTGMALQVVRTDGFLALYNGLSASLCRQMTYSLTRFAIYETMRDYMTKDSQGPLPFYSKVLLGGISGLTGGFVGTPADLVNVRMQNDMKLPLSQRRNYSHALDGLYRVAREEG-LKKLFSGATMASSRGALVTVGQLSCYDQAK-QLVLSTGYLSDNIFTHFLSSFIAGGCATFLCQPLDVLKTRLMNSK-GEYQGVFHCAVETA-KLGPQAFFKGLVPAGVRLVPHTVLTFMFLEQLRKH-FGIKVAT--------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9QZD8-1", "uniprot_id": "DIC_MOUSE", "id": "Q9QZD8-1", "name": "Mitochondrial dicarboxylate carrier", "aln": "--------------MAEARASRWYFGGLASCGAACCTHPLDLLKVHLQTQQEV-KLRMTGMALQVVRTDGFLALYNGLSASLCRQMTYSLTRFAIYETMRDYMTKDSQGPLPFYNKVLLGGISGLTGGFVGTPADLVNVRMQNDMKLPPSQRRNYSHALDGLYRVAREES-LRKLFSGATMASSRGALVTVGQLSCYDQAK-QLVLSTGYLSDNIFTHFVSSFIAGGCATFLCQPLDVLKTRLMNSK-GEYQGVFHCAMETA-KLGPQAFFKGLFPAGIRLIPHTVLTFMFLEQLRKH-FGIKVPTT-------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9UBX3-1", "uniprot_id": "DIC_HUMAN", "id": "Q9UBX3-1", "name": "Mitochondrial dicarboxylate carrier", "aln": "-------------MAAEARVSRWYFGGLASCGAACCTHPLDLLKVHLQTQQEV-KLRMTGMALRVVRTDGILALYSGLSASLCRQMTYSLTRFAIYETVRDRVAKGSQGPLPFHEKVLLGSVSGLAGGFVGTPADLVNVRMQNDVKLPQGQRRNYAHALDGLYRVAREEG-LRRLFSGATMASSRGALVTVGQLSCYDQAK-QLVLSTGYLSDNIFTHFVASFIAGGCATFLCQPLDVLKTRLMNSK-GEYQGVFHCAVETA-KLGPLAFYKGLVPAGIRLIPHTVLTFVFLEQLRKN-FGIKVPS--------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F1QDE0-1", "uniprot_id": "F1QDE0_DANRE", "id": "F1QDE0-1", "name": "Mitochondrial dicarboxylate carrier", "aln": "--------------MTETRVSRWYFGGIASCAAACCTHPLDLIKVHLQTQQEV-KMRMTGMAVQVVRSDGVFALYNGLSASLCRQMSYSMTRFAIYETVRDQIASQNQGPMPFYQKILLAAFGGFTGGFIGTPADMVNVRMQNDMKLPPVLRRNYAHALDGLLRVLKEEG-IRKLFSGASMAASRGALVTVGQLSCYDQAK-QLVLGTGLMTDNIFTHFVASFIAGGCATVLCQPMDVVKTRLMNSK-GEYRGLIHCLSDTG-KLGPKAFYKGLVPAGIRLIPHTVLTFIFLEQLRLY-FGIRVVAAT------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9Y166-1", "uniprot_id": "Q9Y166_DROME", "id": "Q9Y166-1", "name": "", "aln": "-------------MPHQERKSMWFFGGLASVGAAMVTHPLDLIKVTLQTQQG--HLSVAQLIPKLAREQGVLVFYNGLSASVLRQLTYSTARFGVYEAGKKYVNTDSFG-----GKVALAGASGLVGGIVGTPADMVNVRMQNDVKLPPQQRRNYNNAFDGLVRVYRQEG-FKRLFSGATAATARGILMTIGQIAFYDQTK-IYLLATPYFQDNLVTHFTASLVAGTIATTLTQPLDVLKTRSMNAKPGEFNGLWDIVKHTA-KLGPLGFFKGYVPAFVRLGPHTIITFVFLEQLRLK-FGTLN----------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VDM3-1", "uniprot_id": "Q9VDM3_DROME", "id": "Q9VDM3-1", "name": "", "aln": "----MSLRRGGLMSYNQRRIARWYFGGLASSMAAMVTHPIDLIKVLIQTQAE--KLSVFQTTRKIVKEQGPLAMYNGISASMLRQYTYTLARFGIYSVGSGAMDTSTMA-----GKTCLAAIAGGIGGFVGAPADLINVRLQNDVKLPPEKRRNYKHAIDGLVRITREEG-WKNLFNGSSMIALRGAFMTVGQIAFYEQSK-SQMIKLG-MPDYMGTYILASMISSVVATTLTQPIDVVKTRRMNAAPGEYSGLGDVFVKTS-KEGPLAFFKGYVPSLSRLLPHTVLLFLGLEYLRTH-FGYLPEPKQTGAFYRYDDVDD", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q06143-1", "uniprot_id": "DIC1_YEAST", "id": "Q06143-1", "name": "Mitochondrial dicarboxylate transporter", "aln": "------MSTNAKESAGKNIKYPWWYGGAAGIFATMVTHPLDLAKVRLQAAPMP-KPTLFRMLESILANEGVVGLYSGLSAAVLRQCTYTTVRFGAYDLLKENVIPREQLTN-MAYLLPCSMFSGAIGGLAGNFADVVNIRMQNDSALEAAKRRNYKNAIDGVYKIYRYEGGLKTLFTGWKPNMVRGILMTASQVVTYDVFKNYLVTKLDFDASKNYTHLTASLLAGLVATTVCSPADVMKTRIMNGS-GDHQPALKILADAVRKEGPSFMFRGWLPSFTRLGPFTMLIFFAIEQLKKHRVGMPKEDK-------------", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "A1Z787-1", "uniprot_id": "A1Z787_DROME", "id": "A1Z787-1", "name": "", "aln": "-----------MGEDSSRRLPRWWFGGVCAAIAVTGTHPIDLIKVQLQTQSQADRKTVGEILKGIHERSGILGFYNGISASWFRQLTYTTTRFALYEAGKDYVDTQKVS-----SKMALATFAGIVGGIVGVPGDVVTVRLQNDVKLPEEKRRNYKHVFDGLFRIYKEEG-VSSLFRGTVPAVSRAVLLTIGTNAAYDQVKQMLKIATG-AGEGVPLHFATSTIAGCIAVVITQPLDVIKTTFMNAQPGEFSGIGGAFLSTA-KQGPLAFYKGFIPALIRVSPNTIITFVLYEQARMR-FGYLPPDK-------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VVS1-1", "uniprot_id": "Q9VVS1_DROME", "id": "Q9VVS1-1", "name": "", "aln": "MPVFDDHFLGDCHDEPEGLLPRWWFGGFASMCVAFAVAPIDIVKTHMQIQRQ--KRSILGTVKRIHSLKGYLGFYDGFSAAILRQMTSTNIHFIVYDTGKKMEYVDRDS---YLGKIILGCVAGACGSAFGIPTDLINVRMQTDMKEPPYKRRNYKHVFDGLIRIPKEEG-WKALYKGGSVAVFKSSLSTCSQIAFYDIIK-TEVRKNISVNDGLPLHFLTSLGTSIISSAITHPLDVVRTIMMNSRPGEFRTVFQASVHMM-RFGVMGPYRGFVPTIVRKAPATTLLFVLYEQLRLH-FGICSLGGEKYN---------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "A0A6M3Q724-1", "uniprot_id": "A0A6M3Q724_DROME", "id": "A0A6M3Q724-1", "name": "Mitochondrial dicarboxylate carrier", "aln": "-----MDIRAKRVIKTKKIRPRWWSGGVAGAIAQCFTAPFDLIEARMVVIKKD--RGMASNLQQAIRTHGFISLYDGLSAQLLRQLTYTSMRFHLYEMGKEHLDDPAGL----LDKVLVAALAGCVAGVVGTPMELINTRMQVNRALPKETRWNYRNVFDGLYRVTREEG-FTKLYSGCFLSFMRSSLITISQNAAYDQAKQIYAEFFHMKHDNTLLHLISSVTAAFVCGPIIKPIENLRYLRMVDS----RRLINSISYMM-RFGSRGPFRGMVPYVLRMVPNTVITFLSFEQLRVN-FGYIEIEDDE-----------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . *: ** .. . . *:*: :. : : * . :*.*:** ** : : :* *. . .* .. * :::. *:* : * ** :.:**: :: : *. *: * :. : * . *: * . :: :* :. . : * : :: * : * ::* .* * * * : *. * : .* ", "identical_positions": 41, "similar_positions": 63, "identity": "12.81%" }, { "cls_id": "homologset.agr.MGI:1353498", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8VEM8-1", "uniprot_id": "S25A3_MOUSE", "id": "Q8VEM8-1", "name": "Solute carrier family 25 member 3", "aln": "MFSSVAHLARANPFNAPHLQLVHDGLSGPRS----PPAPPRRSRHLAAAAVEE----YSCEFGSMKYYALCGFGGVLSCGLTHTAVVPLDLVKCRMQVDPQKYKGIFNGFSITLKEDGVRGLAKGWAPTLIGYSMQGLCKFGFYEVFKALYSNILGEENTYLWRTSLYLASSASAEFFADIALAPMEAAKVRIQT-QPGYANTLREAVPKMYKEEG-LNAFYKGVAPLWMRQIPYTMMKFACFERTVEALYKFVVPKPRSECTKAEQLVVTFVAGYIAGVFCAIVSHPADSVVSVLNKEKGS------TASQVLQRLGFRGVWKGLFARIIMIGTLTALQWFIYDSVKVYFRLPRPPPPEMPESLKKKLGLTE", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P16036-1", "uniprot_id": "S25A3_RAT", "id": "P16036-1", "name": "Solute carrier family 25 member 3", "aln": "MFSSVAHLARANPFNAPHLQLVHD-VSGPRS----PPGPPRRSRHLAAAAVEG----YSCEFGSMKYYALCGFGGVLSCGLTHTAVVPLDLVKCRMQVDPQKYKGIFNGFSITLKEDGVRGLAKGWAPTLIGYSMQGLCKFGFYEVFKALYSNILGEENTYLWRTSLYLAASASAEFFADIALAPMEAAKVRIQT-QPGYANTLREAVPKMYKEEG-LNAFYKGVAPVWMRQIPYTMMKFACFERTVEALYKFVVPKPRSECTKAEQLVVTFVAGYIAGVFCAIVSHPADSVVSVLNKEKGS------TASQVLQRLGFRGVWKGLFARIIMIGTLTALQWFIYDSVKVYFRLPRPPPPEMPESLKKKLGLTE", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q00325-1", "uniprot_id": "S25A3_HUMAN", "id": "Q00325-1", "name": "Solute carrier family 25 member 3", "aln": "MFSSVAHLARANPFNTPHLQLVHDGLGDLRSSSPGPTGQPRRPRNLAAAAVEEQ---YSCDYGSGRFFILCGLGGIISCGTTHTALVPLDLVKCRMQVDPQKYKGIFNGFSVTLKEDGVRGLAKGWAPTFLGYSMQGLCKFGFYEVFKVLYSNMLGEENTYLWRTSLYLAASASAEFFADIALAPMEAAKVRIQT-QPGYANTLRDAAPKMYKEEG-LKAFYKGVAPLWMRQIPYTMMKFACFERTVEALYKFVVPKPRSECSKPEQLVVTFVAGYIAGVFCAIVSHPADSVVSVLNKEKGS------SASLVLKRLGFKGVWKGLFARIIMIGTLTALQWFIYDSVKVYFRLPRPPPPEMPESLKKKLGLTQ", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q0E8E8-1", "uniprot_id": "Q0E8E8_DROME", "id": "Q0E8E8-1", "name": "Phosphate carrier protein, mitochondrial", "aln": "MFSSFFETARNSPFRTPMSMARCDAAAPVVE------PQPVEGRQIAAAATPVANQQDSCEFGSTKYFALCGIGGILSCGTTHTFVVPLDLVKCRLQVDQAKYKNLVHGFKVTVAEEGARGLAKGWFPTLLGYSAQGLCKFGLYELFKVKYAEIIGEENAYLYRTSLYLAASASAEFFADIALAPFEAAKVKIQT-IPGYANNFREAVPKMLKEEG-VNAFYKGLVPLWMRQIPYTMMKFACFERTVELLYKYVVPKPRADCTKGEQLIVTFAAGYIAGVFCAVVSHPADVVVSKLNQAKGA------SAISVAKSLGFSGMWNGLTPRIIMIGTLTALQWFIYDGVKVALGIPRPPPPEMPASLKAKQH---", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P40035-1", "uniprot_id": "PIC2_YEAST", "id": "P40035-1", "name": "Mitochondrial phosphate carrier protein 2", "aln": "----------MESNKQPRK----------------------------------------IQLYTKEFYATCTLGGIIACGPTHSSITPLDLVKCRLQVNPKLYTSNLQGFRKIIANEGWKKVYTGFGATFVGYSLQGAGKYGGYEYFKHLYSSWLSPG------VTVYLMASATAEFLADIMLCPFEAIKVKQQTTMPPFCNNVVDGWKKMYAESGGMKAFYKGIVPLWCRQIPYTMCKFTSFEKIVQKIYS-VLPKKKEEMNALQQISVSFVGGYLAGILCAAVSHPADVMVSKINSERKANESMSVASKRIYQKIGFTGLWNGLMVRIVMIGTLTSFQWLIYDSFKAYVGLPTTG----------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .. . * : : .:: * :**:::** **: :.********:**: *.. .:** : ::* : : .*: .*::*** ** *:* ** ** *:. :. .::** :**:***:*** *.*:** **: ** * :.*.. :. ** *.* ::*****:.*:* ******* **:.**: *: :*. *:** : : . :*: *:*..**:**::** ****** :** :*. : : :: : : :** *:*:** **:******::**:***..*. . :* . ", "identical_positions": 122, "similar_positions": 97, "identity": "32.71%" }, { "cls_id": "homologset.agr.MGI:1353499", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I6ALC2-1", "uniprot_id": "A0A8I6ALC2_RAT", "id": "A0A8I6ALC2-1", "name": "Tyrosine-protein kinase BAZ1B", "aln": "MAPLLGRKPFPLVKPLPGE----EPLFTIPHTQEAFRTREEYEARLERYSERIWTCKSTGSSQLTHKEAWEEEQEVAELLKEEFPNWYEKLVLEMVHHNTASLEKLVDSAWLEIMTKYAVGEECDFEVGKEKMLKVKIVKIHPLEKVDEEAAEKKSDGTCDSPSSDKENSSQMAQDHQK-ETVVKEDGGRRESINDRARRSPRKLPTSLKKGERKWAPPKFLPHKYDVKLQSEDKIISNVPADSLIRTERPPNKEILRYFIRHNALRAGTGENAPWVVEDELVKKYSLPSKFSDFLLDPYKYMTLNPSTKRKNTGSPDRKPSKKPK----------------RDNSSLSSPLNPKLWCHVHLEKSLNGPPLKVKNSKNSKSPEEHLEEVMKIMSPN--KLHS-FHIPKKGPSTKKPGKHSDKPLKAKGRGKGILNGQKSTGNSKSPSKCVKTP-KTKMKQMTLLDMAKGTQKMTRTPRSSGGVPRSSGKPHKHLPPAALHLIAYYKENKDKEDKKSALSCVISKTARLLSSEDRARLPEELRALVQKRYELLEHKKRWASMSEEQRKEYLKKKRQELKERLREKAKERREKEMLERLEKQKRYEDQELGGRNLPTFRLVDTPEGLPNTLFGDVALVVEFLSCYSGLLLPDAQYPITAVSLMEALSADKGGFLYLNRVLVILLQTLLQDEIAEDYGELGMKLSEIPLTLHSVSELVRLCLRRCDVQEDSEGSDTDDNKDSTPFEDNEVQDEFLEKLETSEFFELTSEEKLRILTALCHRILMTYSVQDHMETRQQMSAELWKERLAVLKEENDKKRAEKQKRKEMEARNKENGKEENVLGKVD--RKKEIVKIENQVEVEADDMISAVKSRRLLSMQAKRKREIQERETKVRLEREAEEERVRKHKAAAEKAFQEGIAKAKLVLRRTPIGTDRNHNRYWLFSNEVPGLFIEKGWVHNSIDYRFKHHRKDHNNLPDDDYCPRSKKAN--------------LGKNASVNAHLGSALE-AVETTVPKQGQNLWFLCDSQKELDELLNCLHPQGIRESQLKERLEKRYQEITHSIHLARKPNLGLKSCDGNQELLNFLRSDLIEVATRLQKGGLGYMEGTS---EFEARVISLEKLKDFGECVIALQASVIKKFLQGFMAPKQKKRKLQS-EDSTKSEEVDEEKKMVEEAKVASALEKWKTAIREAQTFSRMHVLLGMLDACIKWDMSAENARCKVCRKKGEDDKLILCDECNKAFHLFCLRPALYEVPDGEWQCPACQPPTARRNSRGRNYTEESTSEDSEGDESGDEEEEEEEEEEEEEDYEVAGLRLRPRKTIRG-------KQSVIP----AARPGRPPGKKS-HAARRSRPK----DDTEVDELVLQTKRS-SRRQSLELQKCEEILHKLVKYRFSWPFREPVTRDEAEDYYDVIDHPMDFQTMQNKCSCGNYRSVQEFLTDVKQVFANAELYNCRGSHVLSCMEKTEQCLLALLQKHLPGHPYVRRKRRKFPDRLADDEGDSDSESVGQSRGRRQKK--------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9Z277-1", "uniprot_id": "BAZ1B_MOUSE", "id": "Q9Z277-1", "name": "Tyrosine-protein kinase BAZ1B", "aln": "MAPLLGRKPFPLVKPLPGE----EPLFTIPHTQEAFRTREEYEARLERYSERIWTCKSTGSSQLTHKEAWEEEQEVAELLKEEFPNWYEKLVLEMVHHNTASLEKLVDSAWLEIMTKYAVGEECDFEVGKEKMLKVKIVKIHPLEKVDEEAVEKKSDGACDSPSSDKENSSQMAQDLQKKETVVKEDEGRRESINDRARRSPRKLPTSLKKGERKWAPPKFLPHKYDVKLQNEDKIISNVPADSLIRTERPPNKEILRYFIRHNALRAGTGENAPWVVEDELVKKYSLPSKFSDFLLDPYKYMTLNPSTKRRNTGSPDRKPSKKPK----------------RDSSSLSSPLNPKLWCHVHLEKSLNGPPLKVKNSKNSKSPEEHLEGVMKIMSPNNNKLHS-FHIPKKGPAAKKPGKHSDKPLKAKGRGKGILNGQKSTGNSKSPSKCVKTP-KTKMKQMTLLDMAKGTQKMTRTPRSSGGVPRSSGKPHKHLPPAALHLIAYYKENKDKEDKKSALSCVISKTARLLSNEDRARLPEELRALVQKRYELLEHKKRWASMSEEQRKEYLKKKRQELKERLREKAKERREREMLERLEKQKRFEDQELGGRNLPAFRLVDTPEGLPNTLFGDVALVVEFLSCYSGLLLPDAQYPITAVSLMEALSADKGGFLYLNRVLVILLQTLLQDEIAEDYGELGMKLSEIPLTLHSVSELVRLCLRRCDVQEDSEGSETDDNKDSTPFEDNEVQDEFLEKLETSEFFELTSEEKLRILTALCHRILMTYSVQDHMETRQQVSAELWKERLAVLKEENDKKRAEKQKRKEMEARNKENGKEENVLGKVD--RKKEIVKIEQQVEVEADDMISAVKSRRLLSMQAKRKREIQERETKVRLEREAEEERMRKHKAAAEKAFQEGIAKAKLVLRRTPIGTDRNHNRYWLFSNEVPGLFIEKGWVHNSIDYRFKHHRKDHSNLPDDDYCPRSKKAN--------------LGKNASVNAHHGPALE-AVETTVPKQGQNLWFLCDSQKELDELLSCLHPQGIRESQLKERLEKRYQEITHSIYLARKPNLGLKSCDGNQELLNFLRSDLIEVATRLQKGGLGYMEGTS---EFEARVISLEKLKDFGECVIALQASVIKKFLQGFMAPKQKKRKLQS-EDSTKSEEVDEEKKMVEEAKVASALEKWKTAIREAQTFSRMHVLLGMLDACIKWDMSAENARCKVCRKKGEDDKLILCDECNKAFHLFCLRPALYEVPDGEWQCPACQPPTARRNSRGRNYTEESTSEGSEGDESGEEEEEEEEEEEEEEDYEVAGLRLRPRKTIRG-------KQSVIP----AARPGRPPGKKS-HPARRSRPK----DDPEVDDLVLQTKRI-SRRQSLELQKCEDILHKLVKYRFSWPFREPVTRDEAEDYYDVIEHPMDFQTIQNKCSCGNYRSVQEFLTDMKQVFANAELYNCRGSHVLSCMEKTEQCLLALLQKHLPGHPYVRRKRRKFPDRLADDEGDSDSESVGQSRGRRQKK--------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9UIG0-1", "uniprot_id": "BAZ1B_HUMAN", "id": "Q9UIG0-1", "name": "Tyrosine-protein kinase BAZ1B", "aln": "MAPLLGRKPFPLVKPLPGE----EPLFTIPHTQEAFRTREEYEARLERYSERIWTCKSTGSSQLTHKEAWEEEQEVAELLKEEFPAWYEKLVLEMVHHNTASLEKLVDTAWLEIMTKYAVGEECDFEVGKEKMLKVKIVKIHPLEKVDEEATEKKSDGACDSPSSDKENSSQIAQDHQKKETVVKEDEGRRESINDRARRSPRKLPTSLKKGERKWAPPKFLPHKYDVKLQNEDKIISNVPADSLIRTERPPNKEIVRYFIRHNALRAGTGENAPWVVEDELVKKYSLPSKFSDFLLDPYKYMTLNPSTKRKNTGSPDRKPSKKSK----------------TDNSSLSSPLNPKLWCHVHLKKSLSGSPLKVKNSKNSKSPEEHLEEMMKMMSPN--KLHTNFHIPKKGPPAKKPGKHSDKPLKAKGRSKGILNGQKSTGNSKSPKKGLKTP-KTKMKQMTLLDMAKGTQKMTRAPRNSGGTPRTSSKPHKHLPPAALHLIAYYKENKDREDKRSALSCVISKTARLLSSEDRARLPEELRSLVQKRYELLEHKKRWASMSEEQRKEYLKKKREELKKKLKEKAKERREKEMLERLEKQKRYEDQELTGKNLPAFRLVDTPEGLPNTLFGDVAMVVEFLSCYSGLLLPDAQYPITAVSLMEALSADKGGFLYLNRVLVILLQTLLQDEIAEDYGELGMKLSEIPLTLHSVSELVRLCLRRSDVQEESEGSDTDDNKDSAAFEDNEVQDEFLEKLETSEFFELTSEEKLQILTALCHRILMTYSVQDHMETRQQMSAELWKERLAVLKEENDKKRAEKQKRKEMEAKNKENGKVENGLGKTD--RKKEIVKFEPQVDTEAEDMISAVKSRRLLAIQAKKEREIQEREMKVKLERQAEEERIRKHKAAAEKAFQEGIAKAKLVMRRTPIGTDRNHNRYWLFSDEVPGLFIEKGWVHDSIDYRFNHHCKDHTVSGDEDYCPRSKKAN--------------LGKNASMNTQHGTATEVAVETTTPKQGQNLWFLCDSQKELDELLNCLHPQGIRESQLKERLEKRYQDIIHSIHLARKPNLGLKSCDGNQELLNFLRSDLIEVATRLQKGGLGYVEETS---EFEARVISLEKLKDFGECVIALQASVIKKFLQGFMAPKQKRRKLQS-EDSAKTEEVDEEKKMVEEAKVASALEKWKTAIREAQTFSRMHVLLGMLDACIKWDMSAENARCKVCRKKGEDDKLILCDECNKAFHLFCLRPALYEVPDGEWQCPACQPATARRNSRGRNYTEESASEDSEDDES-DEEEEEEEEEEEEEDYEVAGLRLRPRKTIRG-------KHSVIPP---AARSGRRPGKKP-HSTRRSQPKAPPVDDAEVDELVLQTKRS-SRRQSLELQKCEEILHKIVKYRFSWPFREPVTRDEAEDYYDVITHPMDFQTVQNKCSCGSYRSVQEFLTDMKQVFTNAEVYNCRGSHVLSCMVKTEQCLVALLHKHLPGHPYVRRKRKKFPDRLAEDEGDSEPEAVGQSRGRRQKK--------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A2BIL7-1", "uniprot_id": "BAZ1B_DANRE", "id": "A2BIL7-1", "name": "Tyrosine-protein kinase BAZ1B", "aln": "MAPLLGRKPYPLVKPLSEPPGPGEEVYTIEHTKEAFRNKEEYEARLRRYGERIWTCKSTGSSQLTHKEAWEEEQEVTELLQEEYPVWFEKPVLEIVHHNTVPLDKLVDQVWVEILTKYAVGEKCDLMVGNDKTLSVEVVKIHPLENPPEENAEKKMEGACDSPSSDKENAS---QENLKKEPQSKEEESRRESLSDRARRSPRKLPTTMKEEKKKWVMPKFLPHKYDVKLVNEDKVISDVPADNLFRTERPPNKEIMRYFIRHYALRLGSGESAPWVVEDELVKKFSLPSKFSDFLLDPHKFLAENPSTKRKSLSSPEGKPRKRLKNVETGTGGEGAKGDKKKNKDSQNIPLSPTIWSHMQVKK-VNGSPLKMKNSGTSKKSDE----------------ENVLGTPK---SSKKQGDKKSSDPKRR-RKSGLNKTPNSQRLSKKEDKSLGGAKKPRMKQMTLLDLAKSPAAAGSPKKQRRSSTTGSAKLGKPFPPMALHLLRFYKENKGKEDKKTTLSSLLSKAAKALSPEDRSRLPEELKELVQKRWELLEQKRRWALMSEEEKQSVLKQKRQEVKQKLREKAKERREKEMQVRREMSRRYEDQELEGKNLPAFRLFDMPEGLPNTIFGDVAMVVEFLHCYSGLLMPDDQYPITSIALLEALAGEKAGFLYLNRVLVVLLQTLLQDELAEGYSELDMPLSEIPLTMHSVSELVRLCLRPSDAHEEESARGSDDWQSGADFDD-MVSSEFLEKLETAEVFELDPQEKVSLLLALCHRILMTYSVEDHVEAVHQKSAEMWKERVATLKEANDRKRAEKQKRKEQMETKTDGDVLIKAEKKKESTVKKETPKVLPKEEPEPEDMISTVKSRRLMSIQAKKEKEEQERLNKVRMEKEAEEERIRRQKAATEKAFQDAVTKAKLVLRRTPLGTDRNHNRYWLFSDVVPGLYIEKGWVHESIDYSFTLPPEEEPVLTEEEEEEEEVKKEEETEDGEKEDEGSIISASNDISQQGAPSHESSIETTVPKQGQNLWFVCDTPKDFDELLESLHPQGVRESELKIRLQINYQEILHSIHLTKKGNPGLKTCDGHQELLKFLRSDIIEVASRLQKGGLGYLEDTSEFEEFEERVKTLEKLPEFGECVIALQESVIKKFLQGFMAPKQKKKKKTGGEESTTAEEVDDQKKLAEEARVATAVEKWKTAVREAQTFSRMHVLLGMLDACIKWDMSAENARCKVCRRKGEDDKLILCDECNKAFHLFCLRPALYRIPAGEWLCPACQPTIARRSSRGRNYKEDSE----EEEDSEEEDEEESEEEDSEEEHRNTGHSLRSRKKVKTSSKSKMQKKPAKPASRSASKTDTNPSKTSPKSSAKPKSRAAPSSPVDIDELVRQSSKPPSRKKDVELQKCEEILQKIMKFRHSWPFREPVSAEEAEDYQDVITSPMDLTTMQGKFKSSEYHSASDFIEDMKLIFSNAEEYNQPSSNVLTCMSRTEEAFVELLQKSLPGVSYLRRRTRKRAATPSDNSDDDDDDEEEDERSKKQKNGKQGKKASSKRKVEHSRTEKYQTKQK", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*********:******. * ::** **:****.:*******.**.**************************:***:**:* *:** ***:*****..*:**** .*:**:*******:**: **::* *.*::*******: ** .*** :*:**********:* *: * *. **: .****:.************::*: ::**. ************ .***:**:****.*:**********:****** *** *:**.************:*************:*::: ******:. .**: ** *: * :..* . **.*.:*.*::::* :.*.***:*** .**..:* .. : ** .:** *.:... * : * .*: : :* **. .* : . *.:********:**.. . :. . . *.* * :** ****: :*****.:***:::**.::**:*: ** ***:******: *****:****:*:*** ****:::. **:**:*:*::*:********:** * * .:*:***** *:***:***.* *******:*****:***** ******:** *****:::*:***:.:*.**********:*********:**.*.**.* *******:************ .*.:*:... :** :..: *:* *..********:*.*** .:**: :* ************:**:*: :* ***:****:*.*** **:********** :.:.. : * : *** *. : : *.:****:******:::***:::* *** **::*::*****:*::***:*****:.::*****:****:*************: ****:*******:**** *. ::. ::: .. * : :. . .:. : ..: * ::***.*********:**: *::****..*****:***:** **: .**:* ***:*::* * ***:***:****:*****:****:*********:* ** *** ** :**** :********* ****************::* . *:*:.:****::**:.***:**:*:******:***********************************:***************************.:* *** ******. ***.******.*:* * ::* :*:***.***:.**::. :* **.**.:: *:.. * *::.. *.*.. :.: :.:.: . ::*:** *:.: **::.:******:**:*::*:*.********: :***** *** ***: *:*.* ....*:*..:*: *:* :*:*** ** .*:**:** :**:.:: **:* *** .*:**: :* . :::..*.: : :.*.::**: ", "identical_positions": 872, "similar_positions": 391, "identity": "55.72%" }, { "cls_id": "homologset.agr.MGI:1353500", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8R2I0-1", "uniprot_id": "FOXE1_MOUSE", "id": "Q8R2I0-1", "name": "Forkhead box protein E1", "aln": "MTAESAPPPPPQPETLAAVKEERGEAAAAGAGVPAEAAGRGAGGRRRKRPLQRGKPPYSYIALIAMAIAH-APERRLTLG------------------------GIYKFITERFPFYRDNPKK--WQNSIRHNLTLNDCFLKIPREAGRP------------------------------------------GKGNYWALDPNAEDMFESGSFLRRRKRFKRSDLSTYPAYMHD-----AAAAAAAAAAAIFPGAVPAARPAYPGAVYA--GYAPP-LAAPPPVYYPAASP----GPCRVFGLVPERPLSPDLGP-APSAAGGSC-AFAAAAGAAGTGS---FQPAVCTGAR-----PVNPAAYAAAYAGPDG-----AYPQGASSALFAAAAGRLAGPASPPAGGGSGGVEATVDFYGRTSPGQFGA---------ALGPCYNPGGQLGAGGGGAYHSRHATAYPGAVDRFVSAM---------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O00358-1", "uniprot_id": "FOXE1_HUMAN", "id": "O00358-1", "name": "Forkhead box protein E1", "aln": "MTAESGPPPP-QPEVLATVKEERGE-TAAGAGVPGEATGRGAGGRRRKRPLQRGKPPYSYIALIAMAIAH-APERRLTLG------------------------GIYKFITERFPFYRDNPKK--WQNSIRHNLTLNDCFLKIPREAGRP------------------------------------------GKGNYWALDPNAEDMFESGSFLRRRKRFKRSDLSTYPAYMHDAAAAAAAAAAAAAAAAIFPGAVPAARPPYPGAVYA--GYAPPSLAAPPPVYYPAASP----GPCRVFGLVPERPLSPELGP-APSGPGGSC-AFASAGAPATTTG---YQPAGCTGAR-----PANPSAYAAAYAGPDG-----AYPQGAGSAIFAAAG-RLAGPASPPAGGSSGGVETTVDFYGRTSPGQFG----------ALGACYNPGGQLGGASAGAYHARHAAAYPGGIDRFVSAM---------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M2B6T0-1", "uniprot_id": "A0A8M2B6T0_DANRE", "id": "A0A8M2B6T0-1", "name": "", "aln": "---------------MPVVKVESDSPSETTLPVNDSQRAEPQRGRRRKRPLQRGKPPYSYIALISMAIAN-SPDRKLTLG------------------------GIYKFITERFPFYRDNSKK--WQNSIRHNLTLNDCFIKIPREPGRP------------------------------------------GKGNYWALDPNAEDMFESGSFLRRRKRFKRSDFTTYSSYVHE--------------SPVFS-PVQIARSAYANSVYSNMAVSPPYAQQLPSAYYQSSSPNFTAGQSRVFRINSLIGSPNRMGQNAEMIPQQSCRSFSPESGSCSLGGPG-FQHQSCNGETVLSCYSSSSNNMAFAYSGPGHGQTQVSYPQ-ASTQHYGPAGRMAISSLSPIAGDAVG------DPYGRTSPAQLG-----------SFVQYNNSGAVGSSGAYIRHP----AYSGNMDRFVSAT---------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P40466-1", "uniprot_id": "FKH1_YEAST", "id": "P40466-1", "name": "Fork head protein homolog 1", "aln": "-MSVTSREQKFSGKYSSYTAQDRQGLVNAVTCVLSSSSDPVAVSSDYSNSLSIAREVNAYAKIAGCDWTYYVQKLEVTIGRNTDSLNLNAVPGTVVKKNIDIDLGPAKIVSRKHAAIRFNLESGSWELQIFGRNGAKVNFRRIPTGPDSPPTVLQSGCIIDIGGVQMIFILPEQETIISDYCLNHLMPKLLSTYGTNGNNNPLLRNIIEGSTYLREQRLQEEARLQQLDHLHTPLSSSSDVNPIGDPHGDTIMMEEDEEDENYTRGGIRPNTYTSSSNNAVTNGNVPHIENPSDLSLDENRYIKPPQSYASMITQAILSTPEGSISLADIYKFISDNYAFYRFSQMAWQNSVRHNLSLNKAFEKVPKRAGQQGKGMNWKISDEVRRDFLNKWNAGKLSKIRRGASVTRQLQLHMSKFGEIPAPESSSIDPRGIKAQKVKKSLQATSSILGESAPQLQRTQLTGQISTTTSMDVTTNANVNNSSLS", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . . : : * . . ...*. .: :* : . : . .:*:* * *:::.:.. * * :. *: .* . : * :** .. * *. :* .:::*..::**.:: :.: : . : *. . :.. . . . . : . . : . * . . :. . .. . :* .: . . *. . .:* . . .. :* .. :. . . *:: ", "identical_positions": 27, "similar_positions": 99, "identity": "5.57%" }, { "cls_id": "homologset.agr.MGI:1353510", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9Z1I6-1", "uniprot_id": "ARHG1_RAT", "id": "Q9Z1I6-1", "name": "Rho guanine nucleotide exchange factor 1", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MGEVAGGAA-PGPPR-----------------------------SGLVSI--IIGAEDEDFENELEANPEDQNSQFQSLEQVKRRPAHLMALLQHVALQFEPGPLLCCLHADMLSSLGPKEAKKAFLDFYHSFLEKTAVLRVPVP-PSVAFELD-RTRPDLISEDVQRRFIQEVVQSQQAAVTRQLEDFRSKRLMGMTPWEQELSLLEPWIGKDRGNYEARERHVAERLLSHLEEMQHTISTDEEKSAAVVTAISLYMRHLGVR-------TKSGDKKSGRNFFRKKV----------------------------------------------------------------------------------------MGNRRSDEPPKTKKGLSSILDPARWN--------RGEPS------------APDCR-----------HLKVEVD-EKPGPADRKGS---LGISSRDRTVGTPGQDNPGVS---------------------------------------LHPLSVDSLDSREPGVDTPQEP---GDTPPQGPTSLEPLAPPE----STEDNGETESPEPGDDGEPGRSGLEQEP------------------------------------------------------------------EEPPGWRELVPSDTLLGLPKNQVKRQEVISELLVTEAAHVRMLRVLHDLFYQPMAEGGFFPLEELQNIFP-SLDELIEVHSLFLDRLMKRRQE-------SGYLIEEIGDVLLARFDGAEGSWFQKISSRFCSRQSFALEQLKAKQRKEPRFCAFVQEAESRPRCRRLQLKDMIPTEMQRLTKYPLLLQSIGQN-----TEEPAERAKVELAAECCREILHHVNQAVRDMEDLLRLKDYQRRLDLTHLRQSNDPMLSEFKNLDITKKKLVHEGPLTWRLTKDKAVEVHVLLLDDLLLLLQRQDEGCCSSHTSRTLTPTPDGKTMLRPVLRLTS-AMTREVATDHKAFYVIFTWDQEAQIYELVAQTSSERKSWCALITETAGSLKVPAP---------------------------------------------------------------------------------------------ASRPKPRPSPS------------STREPLLSSSENGTGGTEAAP------------------------------------------------------------------ADARTERILN--------------DLLPFC-------------------------RPGPEGQLAATALQKVLSLKQILLSTE----------EDSGAGP-PRDGDG----VPGGGAPGPTHTQEVEENLLSLEVVIK--------QLEELEEEFCRLRP------FLSQLG-------EILSPNLAAPERSAQTGLS---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q61210-1", "uniprot_id": "ARHG1_MOUSE", "id": "Q61210-1", "name": "Rho guanine nucleotide exchange factor 1", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MGEVAGGAA-PGPPR-----------------------------SGLVSI--IIGAEDEDFENELEANSEDQNSQFQSLEQVKRRPAHLMALLQHVALQFEPGPLLCCLHADMLSSLGPKEAKKAFLDFYHSFLEKTAVLRVPVP-PSVAFELD-RTRPDLISEDVQRRFIQEVVQSQQAAVSRQLEDFRSKRLMGMTPWEQELSLLEPWIGKDRGNYEARERHVAERLLSHLEETQHTISTDEEKSAAVVTAISLYMRHLGVR-------TKSGDKKSGRNFFRKKV----------------------------------------------------------------------------------------MGNRRSDEPPKTKKGLSSILDPARWN--------RGEPS------------APDCR-----------HLKVEADAEKPGPADRKGG---LGMSSRDRTVGTPGQDNPGVS---------------------------------------LHPLSTDSVDSREPGVDTPQEP---GDTPPQGPTSLEPLAPPE----STEDNGETESPEPGDDGEPGRSGLELEP------------------------------------------------------------------EEPPGWRELVPPDTLLSLPKSQVKRQEVISELLVTEAAHVRMLRVLHDLFYQPMADGGFFPLDELQNIFP-SLDELIEVHSLFLDRLMKRRQE-------SGYLIEEIGDVLLARFDGAEGSWFQKISSRFCSRQSFALEQLKAKQRKEPRFCAFVQEAESRPRCRRLQLKDMIPTEMQRLTKYPLLLQSIGQN-----TEESTERGKVELAAECCREILHHVNQAVRDMEDLLRLKDYQRRLDLTHLRQSSDPMLSEFKNLDITKKKLVHEGPLTWRVTKDKAIEVHVLLLDDLLLLLQRQDERLLLKSHSRTLTPTPDGKTMLRPVLRLTS-AMTREVATDHKAFYVIFTWDQEAQIYELVAQTSSERKNWCNLITETAGSLKVPAP---------------------------------------------------------------------------------------------ASRLKPRPSPS------------SIREPLLSSSENGTGGAEMAP------------------------------------------------------------------ADARTERLLN--------------DLLPFC-------------------------RPGPEGQLAATALQKVLSLKQILLSTE----------EDSGAGP-PRDGDG----VPGGRAPGPVHTQEIEENLLSLEVAIR--------QLEELEEEFCRLRP------LLSQLG-------GTLSPNLAAPERSAQTGLS---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q92888-1", "uniprot_id": "ARHG1_HUMAN", "id": "Q92888-1", "name": "Rho guanine nucleotide exchange factor 1", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MEDFARGAASPGPSR-----------------------------PGLVPVS-IIGAEDEDFENELETNSEEQNSQFQSLEQVKRRPAHLMALLQHVALQFEPGPLLCCLHADMLGSLGPKEAKKAFLDFYHSFLEKTAVLRVPVP-PNVAFELD-RTRADLISEDVQRRFVQEVVQSQQVAVGRQLEDFRSKRLMGMTPWEQELAQLEAWVGRDRASYEARERHVAERLLMHLEEMQHTISTDEEKSAAVVNAIGLYMRHLGVR-------TKSGDKKSGRNFFRKKV----------------------------------------------------------------------------------------MGNRRSDEPAKTKKGLSSILDAARWN--------RGEPQ------------VPDFR-----------HLKAEVDAEKPGATDRKGG---VGMPSRDRNIGAPGQDTPGVS---------------------------------------LHPLSLDSPD-REPGADAPLEL---GDSSPQGPMSLESLAPPE----STDEGAETESPEPGDEGEPGRSGLELEP------------------------------------------------------------------EEPPGWRELVPPDTLHSLPKSQVKRQEVISELLVTEAAHVRMLRVLHDLFFQPMAECLFFPLEELQNIFP-SLDELIEVHSLFLDRLMKRRQE-------SGYLIEEIGDVLLARFDGAEGSWFQKISSRFCSRQSFALEQLKAKQRKDPRFCAFVQEAESRPRCRRLQLKDMIPTEMQRLTKYPLLLQSIGQN-----TEEPTEREKVELAAECCREILHHVNQAVRDMEDLLRLKDYQRRLDLSHLRQSSDPMLSEFKNLDITKKKLVHEGPLTWRVTKDKAVEVHVLLLDDLLLLLQRQDERLLLKSHSRTLTPTPDGKTMLRPVLRLTS-AMTREVATDHKAFYVLFTWDQEAQIYELVAQTVSERKNWCALITETAGSLKVPAP---------------------------------------------------------------------------------------------ASRPKPRPSPS------------STREPLLSSSENGNGGRETSP------------------------------------------------------------------ADARTERILS--------------DLLPFC-------------------------RPGPEGQLAATALRKVLSLKQLLFPAE----------EDNGAGP-PRDGDG----VPGGGPLSPARTQEIQENLLSLEETMK--------QLEELEEEFCRLRP------LLSQLG-------GNSVP---------QPGCT---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9P7X5-1", "uniprot_id": "A0A8M9P7X5_DANRE", "id": "A0A8M9P7X5-1", "name": "", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MLLFSILVGARFAGVGRTCDSMDYEDAH----------NGRGLSGAQGLNPVMNIIGAEDEDFENDEQPMVDDQCIHFNSIELLKSRPTHLLVFLHHVMLQFDCAPVLCYLHADLMKNLNTKDTKKHFGEFYNTFLEKGAILKVSVP-SNIAPEID-RLRPELINEEQQKRYANEIQFAQSPEILRQLEDFRQKRMMGMTPNERELNDVESHRPTDRIPMDMKEKAVAESLLEKMVEANPSIVPDKDKSNSIFGAVAYYMKYLGVK-------TRAFDNKKSKSGWRPSVPSMLKPWSVN---------------------------------------------------------KQIKPVKPPGIGYDGKQSRLDFEAKQNKQPPHRVSVSDSVTPPGRKTGITVSGSTHGSESSEELPISVSVTPSPDFQTDTVGIINNRTDPKPASEGGEVSPVSTGGT---VSICEPLAVIDVPPEDIQDSGRKKPR------------------------------NVRRSESLCVERRHSRRGGSTRAKQSRSRSDVDLQSTSTSHPLSPSPQHSVSVEGDKTPEIALLTPTFVPAPQQEEIEPRL------------------------------------------------------------LELEQDPLNWRELASSESLHKLSKKEAKRQEVINELFVTEQAHVRMLSVLQTVFSRPLEKQEYMTANEVATIFS-SLDDIIEMHYVFYENLKKLREE-------DEYIVKTISTPLLNRFSGSEGEWFQKLTARFCSYQSWALEQIKSRQKKDPRFNAFILEAESKPQCRRLQLKDIIPIEMQRLTKYPLLLENIAKN-----TEDATEKEKINQAAESCRKILNHVNEEVKQMENLLILKDYQRRLDTSGLKPSNE-LYSEYKTIDLTNRTMLFEGPLTWRVTKEKAIDVHCVLLSDLLVLFQKQDDKMLLKCQSKSNIAVQEGKQMLSPIIKLES-VFLREVATDPKALYVIFTWDSGAQIYELVAQSVGERKNWTEAIKSAVDELKKASK---------------------------------------------------------------------------------------------SNTKLERNSRAGSVPNNIAVPLYGPAHPPLSPTENG-GELLKNR------------------------------------------------------------------VGRFSEKIRESDPPLIDYLAANGFDLLTHS-------------------------HTPPE-KSATVALDEVMCLKRLLVGSISLSDDAQTLGENGGMAPESQDADGTQLSVEESSTEAGPEVEEHEEDVENKGEEEKGISAPLVLSEERMEEVQMRLQA------LEEQLKRLRLVEEDHYKLQEALAKYTLQGGHYN--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A1ZAN6-1", "uniprot_id": "A1ZAN6_DROME", "id": "A1ZAN6-1", "name": "", "aln": "MDDPSIKKRLLDLYTDEHEYDEVQEIPEESSIQPPETSTSHTSTNGSSHSGPGTATGPGATSAGPSAGAPQSPVIVVDSVPELPAPKQKSVKNSKSKQKQKQLANKSKIPRSPSLASSLSSLASSLSGHRDRDKDRDKDRENQNAVPPQTPPLPPSYKQNQMNGDSTAAAGGGVSAPATPTTANNNNASHNNGSIMGGGVQLNQSDNSNPVLQAPGERSSLNLTPLSRDLSGGHTQESTTPATTPSTPSLALPKNFQYLTLTVRKDSNGYGMKVSGDNPVFVESVKPGGAAEIAGLVAGDMILRVNGHEVRLEKHPTVVGLIKASTTVELAVKRSQKLTRPSSVSVVTPSTPILSGRDRTASITGPQPVDSIKRREMETYKIQTLQKMLEQEKLNLERLKSDQNNPSYKLSEANIRKLREQLHQVGAEDAPTVKLQAAAGNKNTALLTPNQIQHLSASATHSNQQFHHLHHHHNLHNNNYPPQQQPASTSPAFLSLLPRSLSSLSLGTRKNKTEKDLTTSSPFGLTTDFLQQQRMSHQAESMSQSMHQHTSTPTSQQFFHPHQQQHRFKETGPTSKGKNKFLISRSLIEEDVPPPLPQRNPPRQLNLDLKNGNASPGGSHLVAPVSDLDRATSPQLNRSQQQQLPSSTDNSPSNAKSKRSKIKTKALSDPKMSTQMFLQMESASAAGAAGGSIEVDGGPPPLPPRLPGMMTEDMSRGSCQNLAQPNSVGTAFNYPLVSTTTAVQNDNLNIAFPLSQRPNIVQQLQQYQQQQQHQMSGGQATGALGQTPNLGKNKHRRVGSSPDNMHPRHPDRITKTTSGSWEIVEKDGESSPPGTPPPPYLSSSHMTVLEDPNENNRGAAAAGPGVFIESHQFTPMAGASSPIPISLHSSHMHAAQSNDTQKEIISMEDENSDLDEPFIDENGPFNNLTRLLEAENVTFLAIFLNYVISNSDPAPLLFYLITELYKEGTSKDMRKWAYEIHSTFLVPRAPLSWYRQDESLAREVDNVLQLEYDKVEILRTVFLRSRKRAKDLISEQLREFQQKRTAGLGTIYGPTDDKLAEAKTDKLREQIIDKYLMPNLHALIEDENGSPPEDVRKVALCSALSTVIYRIFNTRPPPSSIVERVHHFVSRDKSFKSRIMGKNRKMNVRGHPLVLRQYYEVTHCNHCQTIIWGVSPQGYHCTDCKLNIHRQCSKVVDESCPGPLPQAKRLAHNDKISKFMGKIRPRTSDVIGNEKRSRQDEELDVELTPDRGQASIVRQPSDRRPDAN---ISIRSNGNTSCNTSGLNTTDLQSSFHGSCANDSINPGGGAGCNMDLSTSVASTTPSTSGSVAAGLSAFAELNALDTVDKEARRERYSQHPKHKSAPVSVNRSESYKERLSNKRNRNSRRKTSDPSLSSRPNDEQLDLGLSNATYVGSSNSSLSSAGGSESPSTSMEHFAAPGAAGGVQVPPMGLNQNQHPHLLIQQHAQQYCQQDSFQAGLAGAAGSSAASNSSFWNAGHPLPVARWTLESEDEDDVNEADWSSMVAAEVLAALTDAEKKRQEIINEIYQTERNHVRTLKLLDRLFFLPLYESGLLSQDHLLLLFPPALLSLREIHGAFEQSLKQRRIE-------HNHVVNTIGDLLADMFDGQSGVVLCEFAAQFCARQQIALEALKEKRNKDEMLQKLLKKSESHKACRRLELKDLLPTVLQRLTKYPLLFENLYKVTVRLLPENTTEAEAIQRAVESSKRILVEVNQAVKTAEDAHKLQNIQRKLDRSSYD------KEEFKKLDLTQHHLIHDG--NLTIKKNPSVQLHGLLFENMIVLLTKQDDKYYLKN---LHTPLSITNKPVSPIMSIDADTLIRQEAADKNSFFLIK--MKTSQMLELRAPSSSECKTWFKHFSDVAARQSKNRSKNASSNHDTSISDPALAAIPHSNTKESLELSTDTVQPLAATATLTTTPLAPMLPIATVTPAPATNNSNVSSLTGVQLRNPQRDATASESDADYVNTPKPRSSQNEVN---RTMSIRSTGEPIQKYSANGTEANDVTLRHSQSTRESVRPGSTGEERNSTYGMVGGNSKRDSASIVCSNNSNNTRTLLMQSPLVDPTAIQVSISPAHTAEPVLTPGEKLRRLDASIRNDLLEKQKIICDIFRLPVEHYDQIVDIAMMPEAPKDSADIALAAYDQIQTLTKMLNEYMHVTPEQEVSAVSTAVCGHCHEKEKLRKKVAPSSSFSSSPPPLPPPNRQHAQAQAQIPPSRLMPKLQTLDLDEVAIHEDDDGYCEIDELRLPAIPSKPHERPTTPLAPFNTEPKTSQSVIDASKRQSTDAVPEGLLEQEPLEGDKTETKGEDNEVKTVPSDKLSESCNEERQCVEADITKEVADPTTSKNEAAASVDELPSQSREIKTAENASKSVADKKEDNEETIEEGVASTVDSSTQTSPTESPKETDKLTGGSSSTCGPNRIQHASVLEPSVPCHALSSIVTILNEQISMLLPKINERDMERERLRKENQHLRELLSALHDRQRVDEVKETPFDLKKLMHAEDVEFDDDIDAISNSSLTPTPTPIPTASPSASGQVETAEAMRITSTEDEE", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "A0AB13A992-1", "uniprot_id": "A0AB13A992_DANRE", "id": "A0AB13A992-1", "name": "Rho guanine nucleotide exchange factor 2", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MGPEDLPDLMDTMSSSPPPSPRPSCLSFS----------------------PSHCSPPMSIDPAHVTLRSPVTRHLTSIDPWRRHSWEPGAVAQGYPPNDTRSVSLEDLDPDEMSLVLNGALRSKRAREVRRSVTQASLTSLTEEEVGTEHQDHHRSALEEQSNQMHGCSASAPSLCMMQQMPRSSAPRPRSYCHESNLHHQIGGSSNSIDSEYAALGLDTDRRQVKAKRQENKEDLSGNRLERTLSFLRKMTANRKNKEKERMREREREAR-------EREARYSNGHLFNCLTVSG-------------------------------------------------------------------------------------TTLCSACNKSITAKEALSCPTCNVTIHN-------RCRDT-------LPN------------------CVKMKQKQQKMALMRNNSAYQNVTLRNKAHLKERPSSAIYPSDSLR------------------------------------QSLLGSRRGRSSLLLSKSVSTNNIAGTLNDDSPLGLRRILSQSTDSLNFRSRTMSMESLNDEGECYVSSLLEDLDCE-------------------------------------------------------------GPEFEADSWSMAVDSSYLQTHRKDVIKRQDVIYELIQTELHHVRTLRIMDCVFRRGMLEEVQLEPGVVHALFP-CLERLLSIHTHFLTQLLARRAHSLQPGSTNNFTITQISDVLIKQFSGQFADDMLKAYSEFCSRHMKAVKLYKELLARDKRLQLFIRRVSRGPLLRRHGFQECILLVTQRITKYPVLLQRIHDN----TKDNLEEAAGLSQALACLRELLCSVDQQVLELERTHRLQEIRSRVDPRAEAKLRS--GALFRPAELLRRQLIHEGTLLWKTPSSRLKDVQVLLMTDILVFLQEKDQRFIFAS------------LDKSAVVSLQS-LLVRDIANQERGLFLISSESSPPEMYELYAASKDDRNTWLRLIQQTIGSCPSREE--------------------------------------------------------------------------------------FPLIETEDKALLRRLKADIQQKDSEVLELLQERVTLFSDLAEVMGGYEVMLP-------------------------------------------------------------------ACSRNLFR----------------AESP-------------------------QAPRGEQLLTQAITEVDRLTELLLGSG-------LEVPLPCNSNGHHNPPGSLVINGQEVLVNGSQENQAAQDGNGNQMEDKTPSEEVSQRLVNLSAQLHALQG-----VVIRQDTILELCLRESPVSQTPSGARTVRSLSRDGASDMGSVGELALLQRQHSLLQEELVRLRGADGKLRDSERVRAHLEKQLRDMKTNSAALGDRGGTAGSQAPSNRRESDTDPNTDTPLASQESMDQSDGLQECSDVEVDVISDDDDDDEVDSRVSPRSESPRDLQDIPEESETATDPRERDASHC----------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . .: .. . * . . . . : . . * : : : . .:: :: : : * * * : . .: . :: * . *: . : * : : . : .: : . : .: . . : . . : . . . * . : . . . : .* . .. * . ***::* *: ** *** * ::. :* : . : : :*. .* : .:* * * * . . : *. * *.* . : : :.**: : *:: * :: : :: . . ** ::: : **:****:*:: : . :: * :. * . :.:* *:: * * *:: : ::* :: :: .: ::.:* .. ::: :*: :::::: .:*: .:: : : : *: * : ..:::: . .:: ** * : .: :.* : .. . * . . . : :. : . . * :: *..:* :: : : :. :: : . ", "identical_positions": 67, "similar_positions": 206, "identity": "2.59%" }, { "cls_id": "homologset.agr.MGI:1353511", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D4ABT9-1", "uniprot_id": "D4ABT9_RAT", "id": "D4ABT9-1", "name": "", "aln": "---------------------------------------------------------------------------------------------------MGRKPGPGAQ---------------------------ELAEEEA----------------------------------------------RTCCGCRFPLLLALLQLALGIAVTVLGFLMASISPSLLVRDTPFWAGIIVCVVAYLGLFMLCVSYQVDER----TCVQFSMKVFYFLLSALGLMVCTLAVAFAAHHYSLLAQ-------FTCETSLDSCQCRLPSAEPLSRAFVYRDVTDCSSITGTFKLFLVIQMVLNLVCGLVCLLACFVMWKHRYQVFYVGVGLRSLMASDGQQQKA", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q62147-1", "uniprot_id": "SSPN_MOUSE", "id": "Q62147-1", "name": "Sarcospan", "aln": "---------------------------------------------------------------------------------------------------MGRKPSPRAQ---------------------------ELPEEEA----------------------------------------------RTCCGCRFPLLLALLQLALGIAVTVLGFLMASISPSLLVRDTPFWAGSIVCVVAYLGLFMLCVSYQVDER----TCVQFSMKVFYFLLSALGLMVCMLAVAFAAHHYSLLAQ-------FTCETSLDSCQCKLPSSEPLSRAFVYRDVTDCTSVTGTFKLFLIIQMVLNLVCGLVCLLACFVMWKHRYQVFYVGVGLRSLMASDGQLPKA", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q14714-1", "uniprot_id": "SSPN_HUMAN", "id": "Q14714-1", "name": "Sarcospan", "aln": "---------------------------------------------------------------------------------------------------MGKNKQPRGQQRQGGPPAADAAGPDDMEPKKGTGAPKECGEEEP----------------------------------------------RTCCGCRFPLLLALLQLALGIAVTVVGFLMASISSSLLVRDTPFWAGIIVCLVAYLGLFMLCVSYQVDER----TCIQFSMKLLYFLLSALGLTVCVLAVAFAAHHYSQLTQ-------FTCETTLDSCQCKLPSSEPLSRTFVYRDVTDCTSVTGTFKLFLLIQMILNLVCGLVCLLACFVMWKHRYQVFYVGVRICSLTASEGPQQKI", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AB40ED77-1", "uniprot_id": "A0AB40ED77_DANRE", "id": "A0AB40ED77-1", "name": "", "aln": "-------------------------------------------------------------------------------------------------MGLGMNPKVGGNQSSEKKAKAETG---------------GPVPEEA----------------------------------------------QKCCGCRFPLLVALLQLLLGIAVAAVAFLMLAISSSLLARETPHWAGIIMCVVSLLGFVLFCITRVPDER----ALLQFVIKLLYFFLCTMGLVMSVVVIAFQCYHYTLTNS-------FSCREMREDCICTLDPEDPIARMFVFSAVSDCSDITSTLPMYYLLQVLLNLAQAIVCLLGAFLIWKHRYQVFFAGLQTGSPAAQHWQKA--", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VYR3-1", "uniprot_id": "Q9VYR3_DROME", "id": "Q9VYR3-1", "name": "Sarcospan", "aln": "MPVQQVRPVSTYDNLGVSQSRQLTAGMAGEPETEVEVELNGSHTSHSIAAVKAALNDAKSKFFGINNYESPMASKSAAVTTIAKPEPRYQNVPQRDELPAVAAPDPPAQPAQPTAPVSDHSRALRYATTYEQIPLSDMEAPQASQAVYMSTTVPQNMKGMKIAGRHTPTRNSLRHSRMIVVNHKNHDSLQATRNLNISRQLLVMQLAVGLFIVGLAVWILILAPNASILINPYLSGLSLLLASIAGLILLRRDHKITEHRPQTNSCYKVLLAESYVFTGLALIFCCLALVCAAIEFAELISSADGECGPTSSSLLSYHNCTCLAAGEVVANYSSEAPMAFAVGQEEASQNDGCAELRIEWKYLLAFSMALNTLGIVATFLYITLFICCHRKREHFYTSV", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .: :. : . .:. : ::** :*: :. :.. : ::.. .*. :* : :.: *:.:: *: : :.: :.* .. :.:. . .:: . :. . * . : : : : ::.: .: .:: : . . ", "identical_positions": 9, "similar_positions": 73, "identity": "2.26%" }, { "cls_id": "homologset.agr.MGI:1353554", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0ABK0LWT5-1", "uniprot_id": "A0ABK0LWT5_RAT", "id": "A0ABK0LWT5-1", "name": "", "aln": "MRMGKKEKKGWGGTREKQPSGDEDGRSGGEGEEPRSSLPGESCLHLRIPNRLAEESVEPPGAEIRMFRFMRDVEPEDPMFLMDPFAIHRQHMSRMLSGGFGYSPFLSITDGNMPATRPASRRMQ-AGAVSPFGMLGMSGGFMDMFGMMNDMIGNMEHMAAGGNCQTFSSSTVISYSNTGDGAPKVYQETSEMRSAPGGIRETRRTVRDSDSGLEQMSIGHHIRDRAHILQRSRNHRTGDQEERQDYINLDESEAAAFDDEWRRETSR-------------------------------------------YRQQRPLEFRR-------------------------------HEASVG---------------GGRRAEGPPRLAIQGPEDS-------------------PSRQSRRYDW--------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q15773-1", "uniprot_id": "MLF2_HUMAN", "id": "Q15773-1", "name": "Myeloid leukemia factor 2", "aln": "-----------------------------------------------------------------MFRFMRDVEPEDPMFLMDPFAIHRQHMSRMLSGGFGYSPFLSITDGNMPGTRPASRRMQQAGAVSPFGMLGMSGGFMDMFGMMNDMIGNMEHMTAGGNCQTFSSSTVISYSNTGDGAPKVYQETSEMRSAPGGIRETRRTVRDSDSGLEQMSIGHHIRDRAHILQRSRNHRTGDQEERQDYINLDESEAAAFDDEWRRETSR-------------------------------------------FRQQRPLEFRR-------------------------------LESSGA---------------GGRRAEGPPRLAIQGPEDS-------------------PSRQSRRYDW--------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q99KX1-1", "uniprot_id": "MLF2_MOUSE", "id": "Q99KX1-1", "name": "Myeloid leukemia factor 2", "aln": "-----------------------------------------------------------------MFRFMRDVEPEDPMFLMDPFAIHRQHMSRMLSGGFGYSPFLSITDGNMPATRPASRRMQ-AGAVSPFGMLGMSGGFMDMFGMMNDMIGNMEHMAAGGNCQTFSSSTVISYSNTGDGAPKVYQETSEMRSAPGGIRETRRTVRDSDSGLEQMSIGHHIRDRAHILQRSRNHRTGDQEERQDYINLDESEAAAFDDEWRRETSR-------------------------------------------YRQQRPLEFRR-------------------------------HEASVG---------------GGRRAEGPPRLAIQGPEDS-------------------PSRQSRRYDW--------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9NKV0-1", "uniprot_id": "MLF_DROME", "id": "Q9NKV0-1", "name": "Myeloid leukemia factor", "aln": "--------------------------------------------------------MSLFGALMGDFDDDLGLMNNHMNHTMNAMNMQMRSMNRLMN-SFMPDPFMQVSPFDQGFQQNALMERPQMPAMPAMGLFGMP--------MMPNFNRLLNADIGGNSGASFCQSTVMTMSSGPDGRPQIYQASTSTKTGPGGVRETRRTVQDSRTGVKKMAIGHHIGERAHIIEKEQDMRSGQLEERQEFINLEEGEAEQFDREFTSRASRGAVQSRHHAGGMQAIMPARPAAHTSTLTIEPVEDDDDDDDDCVIQEQQPVRSSAGRHYSSAPTAPQNSGNIATAAAPTPTSSPTTYDTSNGNNNNYVSSRRSYLRNGHGHSLATPRRPLRTPPSSPLATVSTSPSIHPHPYAANPRRQQRAVKHFHTEDEAASSYKAVKRGKKK", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * .: :. . *:.: :: : *.*::. .* .**:.:: : : * . *:..:*::**. ** :: :: .*.. :*..***:: *. ** *::** ::. ::.***:*******:** :*:::*:***** :****:::.:: *:*: ****::***:*.** ** *: .:** ::*:*:. ::* . * :: ..** .:: * .* * **.* . ", "identical_positions": 77, "similar_positions": 93, "identity": "17.46%" }, { "cls_id": "homologset.agr.MGI:1353557", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "F1M6Q1-1", "uniprot_id": "F1M6Q1_RAT", "id": "F1M6Q1-1", "name": "", "aln": "-------------------------------------------------------------------------------MDLGSDAGSSSSSSRASSQSNSTKVTPCSECKSSSSPGGSLDLVSALEDYEEPFPVYQKKVIDEWAPEEDGE-----------EEEEEDDR---GYRDDRCPAREPGDVSARIGGSGSGNRSAATTMPSP--MPNGNLHPHDPQDLRHNGNLVIAGRPNASRVPR------------------------------------------------------RPIQKTQPPGNRRGGRNRASGGLCLQPPDGGMRVPEEPPAPPMDWEALEKHLAGLQFREQEVRNQGQARTNSTSAQKNERESIRQKLALGSFFDDGPGIYTSCSKSGKPSLSSRLQSGMNLQIC---FVNDSGSDKDSDADDSKTETSLDTPLSPMSKQSSSYSDRDTTEEESESLDDMDFLTRQKKLQAEAKMALAMAKPMAKMQVEVEKQNRKKSPVADLLPHMPHISECLM---KRSLKPTDLRDMTIGQLQVIVNDLHSQIESLNEELVQLLLIRDELHTEQDAMLVDIEDLTRHAESQQKHMAEKMPSK------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P0DPB4-1", "uniprot_id": "SCHI1_MOUSE", "id": "P0DPB4-1", "name": "Schwannomin-interacting protein 1", "aln": "---------------------------------------------------MERSEQRVRAAWDCDPGKQADRDYREDGMDLGSDAGSSSSS-RASSQSNSTKVTPCSECKSSSSPGGSLDLVSALEDYEEPFPVYQKKVIDEWAPEEDGE-----------EEEEEDDR---GYRDDGCPAREPGDVSARIGSSGSGSRSAATTMPSP--MPNGNLHPHDPQDLRHNGNVVVAGRPNASRVPR------------------------------------------------------RPIQKTQPPGSRRGGRNRASGGLCLQPPDGGTRVPEEPPAPPMDWEALEKHLAGLQFREQEVRNQGQARTNSTSAQKNERESIRQKLALGSFFDDGPGIYTSCSKSGKPSLSARLQSGMNLQIC---FVNDSGSDKDSDADDSKTETSLDTPLSPMSKQSSSYSDRDTTEEESESLDDMDFLTRQKKLQAEAKMALAMAKPMAKMQVEVEKQNRKKSPVADLLPHMPHISECLM---KRSLKPTDLRDMTIGQLQVIVNDLHSQIESLNEELVQLLLIRDELHTEQDAMLVDIEDLTRHAESQQKHMAEKMPAK------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P0DPB3-1", "uniprot_id": "SCHI1_HUMAN", "id": "P0DPB3-1", "name": "Schwannomin-interacting protein 1", "aln": "---------------------------------------------------MERSGQRVTT-WDCDQGKHSDSDYREDGMDLGSDAGSSSSSSRASSQSNSTKVTPCSECKSSSSPGGSLDLVSALEDYEEPFPVYQKKVIDEWAPEEDGE-----------EEEEEDERDQRGYRDDRSPAREPGDVSARTRSGGGGGRSATTAMPPP--VPNGNLHQHDPQDLRHNGNVVVAGRPSCSRGPR------------------------------------------------------RAIQKPQPAGGRRSGRGPAAGGLCLQPPDGGTCVPEEPPVPPMDWEALEKHLAGLQFREQEVRNQGQARTNSTSAQKNERESIRQKLALGSFFDDGPGIYTSCSKSGKPSLSSRLQSGMNLQIC---FVNDSGSDKDSDADDSKTETSLDTPLSPMSKQSSSYSDRDTTEEESESLDDMDFLTRQKKLQAEAKMALAMAKPMAKMQVEVEKQNRKKSPVADLLPHMPHISECLM---KRSLKPTDLRDMTIGQLQVIVNDLHSQIESLNEELVQLLLIRDELHTEQDAMLVDIEDLTRHAESQQKHMAEKMPAK------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M6YZD9-1", "uniprot_id": "A0A8M6YZD9_DANRE", "id": "A0A8M6YZD9-1", "name": "", "aln": "----------------------------------------------------------------------------------------------MSSVEEQDRICQHIHQKNILRMDG------------------LKEKERERGDEKESD-----------ETEEDAEG-------------------------------AALLWQEG--YPEDDLG-----------------------------------------------------------------------------------------------------------------------LPIMHWEDLGLRIAELEKQQEERRQREKDLDRLTVDWPDIRGLSNHRETYEDMEDDCN--------SRLTSLTSRLQSQMNLQLC---FINNSESEEEEEEIEAKKEVTKQSSKSGSSQQ---------LEKERGSSSASPKKTKSRGFKNDVRAALSVLRHKLRLEQKQ---------------TIPPSEAVRE---RKHYERNDLKNFSLKELKALRTSLSKDIHDLSSELVGRLLTRDQLRTEQDAMLLEVQDMTSL---------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A8DYY6-1", "uniprot_id": "SCHI1_DROME", "id": "A8DYY6-1", "name": "Schwannomin-interacting protein 1 homolog", "aln": "MDIYITKGITNPNYPGFQKFAHTLSDDYIEYSDMECNESDLTDSDREDDPTFPSKMAKESGSETFKNGQDSILSNCDNGNTYISEEESVNRSENIPDIVNENYSATSENSKRALQKPDLIYNLSQNYTTNPEFPSWSCTINSKYEGQLQGQSPIDIVGDFGGEVEREFELLLTGYKNKKEADELKGSNLDKICDAELSNGTEALKQTSSTRLSGNSTRKNKKKNTPYGHQIVKTKHPKPSHDERQLPPDTFDYKTYSQRKYIICDADQYSSVPEKNKNDSPNLNQAEIPNMSSLEIGGSGSQQNLDEDNNKVASRKYSNQSRWSQYLEDPIKYSKDPCSTMVLEQFDAYKIANDMDVETLQNHYKKVKQIEKKRRFNRDEIRKRLAIGDKDSLNNDIKKEEFLTGSDNESYSSDSETCPKLSSGVLRKQSEFCETKRNKEFENDKIFQKNQINQDKSMNHMNGNPIGTTDYPSDENLFFFANQSKLQIEVRIALAQSKEIAQMKVKARKHG--VTPIVDVIRSMLCDVGIKMNSNHRWISRQLLTGIQVPTLQLLVNNLQEYIENLNVTLLESLKERDDLNSDQDDILHDLEKINNFFVFQQQSGQQVNKIVRHGHLD", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .. :. . * . : : :.: * *.: : : . .. . * * : : : ::: : . * .:: : . . : . : :* ::. : ::* : . : :.: :. .:. : * . :.. :: :.: **: : ::: : : :: . * .: : *: : ..* . *..*. *: * **:*.::** :* :::.:. ", "identical_positions": 24, "similar_positions": 97, "identity": "3.88%" }, { "cls_id": "homologset.agr.MGI:1353561", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9WV55-1", "uniprot_id": "VAPA_MOUSE", "id": "Q9WV55-1", "name": "Vesicle-associated membrane protein-associated protein A", "aln": "MASASGAMAKHEQILVLDPPSDLKFKGPFTDVVTTNLKLQNPSDRKVCFKVKTTAPRRYCVRPNSGIIDPGSIVTVSVMLQPFDYDPNEKSK----HKFMVQTIFAP-----PNISDMEAVWKEAKPD---ELMDSKLRCVFEMPNENDKLNDME---PSKAVP--------------LNASKQDGPLPKPHSVSLNDTETRKLMEECK---RLQGEMMKLSEENRHLRDEGLRLR------KVAHSDKPGSTSAVSFRDNVTSPLPSLLVVIAAIFIGFFLGKFIL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9Z270-1", "uniprot_id": "VAPA_RAT", "id": "Q9Z270-1", "name": "Vesicle-associated membrane protein-associated protein A", "aln": "MASASGAMAKHEQILVLDPPSDLKFKGPFTDVVTTNLKLQNPSDRKVCFKVKTTAPRRYCVRPNSGVIDPGSIVTVSVMLQPFDYDPNEKSK----HKFMVQTIFAP-----PNISDMEAVWKEAKPD---ELMDSKLRCVFEMPNENDKLNDME---PSKAVP--------------LNASKQDGPLPKPHSVSLNDTETRKLMEECK---RLQGEMMKLSEENRHLRDEGLRLR------KVAHSDKPGSTSAVSFRDNVTSPLPSLLVVIAAIFIGFFLGKFIL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9P0L0-1", "uniprot_id": "VAPA_HUMAN", "id": "Q9P0L0-1", "name": "Vesicle-associated membrane protein-associated protein A", "aln": "MASASGAMAKHEQILVLDPPTDLKFKGPFTDVVTTNLKLRNPSDRKVCFKVKTTAPRRYCVRPNSGIIDPGSTVTVSVMLQPFDYDPNEKSK----HKFMVQTIFAP-----PNTSDMEAVWKEAKPD---ELMDSKLRCVFEMPNENDKLNDME---PSKAVP--------------LNASKQDGPMPKPHSVSLNDTETRKLMEECK---RLQGEMMKLSEENRHLRDEGLRLR------KVAHSDKPGSTSTASFRDNVTSPLPSLLVVIAAIFIGFFLGKFIL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9W4N8-1", "uniprot_id": "Q9W4N8_DROME", "id": "Q9W4N8-1", "name": "", "aln": "MSKS-----LFDLPLTIEPEHELRFVGPFTRPVVTIMTLRNNSALPLVFKIKTTAPKRYCVRPNIGKIIPFRSTQVEICLQPFVYDQQEKNK----HKFMVQSVLAPM---DADLSDLNKLWKDLEPE---QLMDAKLKCVFEMPTAEANAENTS---GGGAVGGGTGAAGGGSAGANTSSASAEALESKPKLSSEDKFKPSNLLETSESLDLLSGEIKALRECNIELRRENLHLKDQITRFRSSPAVKQVNEPYAPVLAEKQIPVFYIAVAIAAAIVSLLLGKFFL", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q6Q595-1", "uniprot_id": "SCS22_YEAST", "id": "Q6Q595-1", "name": "Vesicle-associated membrane protein-associated protein SCS22", "aln": "---------------MRIVPEKLVFKAPLNKQSTEYIKLENDGEKRVIFKVRTSAPTKYCVRPNVAIIGAHESVNVQIVFLGLPKSTADDEMDQKRDKFLIVTLPIPAAYQNVEDGELLSDWPNLEEQYKDDIVFKKIKIFHSVLPKRKPSGN-------------------------------HDAESARAPSAGN--------------------------------------------------------------GQSLSSRALLIITVIALLVGWIYY----", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P40075-1", "uniprot_id": "SCS2_YEAST", "id": "P40075-1", "name": "Vesicle-associated membrane protein-associated protein SCS2", "aln": "------------MSAVEISPDVLVYKSPLTEQSTEYASISNNSDQTIAFKVKTTAPKFYCVRPNAAVVAPGETIQVQVIFLGLTEEPAADFK--CRDKFLVITLPSP---YDLNGKAVADVWSDLEAEFKQQAISKKIKVKYLISPDVHPAQNQNIQENKE-----------------TVEPVVQDSEPKEVPAVVNEKEVPAEPETQPPVQVKKEEVPPVVQKTVPHENEKQTSNS-----TPAPQNQIKEAATVPAENESSSMGIFILVALLILVLGWFYR----", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * : .*:. . .: * . : **::*:** ****** . : . *.: : : . . .**:: :: * : : * : : : : : *:: . : : . . : : : :.: .:. : ", "identical_positions": 20, "similar_positions": 50, "identity": "6.97%" }, { "cls_id": "homologset.agr.MGI:1353562", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "F1LX27-1", "uniprot_id": "F1LX27_RAT", "id": "F1LX27-1", "name": "", "aln": "----------------------------------------------------------MLKSLTVKCNKVKPMEGRTE---------------------------------------------------KQPCP-------HLSSGSQPSIAQGENQSENESLMSR-TPATVEKSHS--KEDNS-------------------------------------------------------------TGENSLRGSTTNPDTECPAELTGTISEMEQTRTRKE--KPASIKTKVFETS-------------IINEYTDAHLHNLVERMRERTAFYKRTLTEGENSPEL-------------------------------------------EASSHTATSTDISPRQEINSKPKEHHH-----KLQRVPVKEYLRSMRLP-----------------------RSIDSYTDRIYLLWLLLVTIAYNWNCWLLPVRLVFPCQTPDNRNYWIITDIICDIIYLGDILLIQPRLQFVRGGEIIVDSNELKRHYRSSTKFQMDVASLLPFEVLYIFFG-VNPIFRTNRILKYTSFFEFNHHLESIMDRAYVYRIIRTTGYLLFLLHINACVYYWASDYEGIGSTKWVYNGEGNKYLRCFYWAVRTLITIGGLPEPQTSFEIVFQLLNFFSGVFVFSSLIGQMRDVIGAATANQNNFHVCMDHIIAYMNKYSIPQSTQHRVRTWLEYTWHSQRILDESNLLETLPTAMQLSVAIDINFNIIDKVELFKGCDTQMIYDLLLRLKSTIYLPGDFVCKKGEIGKEMYIIKHGEVQVLGGPDGAQVLVTLKAGAVFGEISLLAKG--GGNRRTADVVAHGFANLLTLDKKTLQEILLHYPTSKKLLMKKAKVLLSQKGKNTQAIPP--RTRPAFLFPPKEETPRMLKVL--LGNTGKVDLGRLLKGKRKQTTQK----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9JJZ9-1", "uniprot_id": "CNGB3_MOUSE", "id": "Q9JJZ9-1", "name": "Cyclic nucleotide-gated channel beta-3", "aln": "----------------------------------------------------------MLKSLTVKFNKVNPMEGRME---------------------------------------------------KKLCP-------NLSSLSQPTIAQGDNQSEKEPLRSR-TPITFEKSHS--KEDNS-------------------------------------------------------------TGENSLRDFTPNPDPECRAELTRTMAEMEKTRTGKE--RPVSFKTKVLETS-------------IINEYTDAHLHNLVERMRERTALYKKTLTEEENFPEV-------------------------------------------EASSQTAMSTNISPKQENNSKLKEHQDTF-SFKPQRVPVKEHLRRMILP-----------------------RSIDSYTDRVYLLWLLLVTIAYNWNCWLLPVRLVFPCQTPDNKNYWIITDIVCDIIYLCDILLIQPRLQFVRGGEIIVDSNELKRNYRSSTKFRMDVASLLPFEVLYIFFG-VNPIFRANRILKYTSFFEFNHHLESIMDKAYVYRVIRTTGYLLFLLHINACVYYWASDYEGIGSTKWVYNGEGNKYLRCFYWAVRTLITIGGLPEPQTSFEIVFQFLNFFSGVFVFSSLIGQMRDVIGAATANQNYFQACMDHIIAYMNKYSIPQSVQYRVRTWLEYTWNSQRILDESNLLENLPTAMQLSIALDINFSIIDKVELFKGCDTQMIYDLLLRLKSTIYLPGDFVCKKGEIGKEMYIIKHGEVQVLGGPDGAQVLVTLKAGSVFGEISLLAKG--GGNRRTADVVAHGFANLLTLDKKTLQEILLHYPTSKKLLMKKAKILLSQKGKTTQAIPA--RPGPAFLFPPKEETPRMLKVL--LGNTGKVDLGRLLKGKRKTTTQK----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9NQW8-1", "uniprot_id": "CNGB3_HUMAN", "id": "Q9NQW8-1", "name": "Cyclic nucleotide-gated channel beta-3", "aln": "----------------------------------------------------------MFKSLT-KVNKVKPIGENNE---------------------------------------------------NEQSSRRNEEGSHPSNQSQQTTAQEENKGEEKSLKTKSTPVTSEEPHTN-IQDKL-------------------------------------------------------------SKKNSSGDLTTNPDPQNAAEPTGTVPEQKEMDPGKE--GPNSPQNKPPAAP-------------VINEYADAQLHNLVKRMRQRTALYKKKLVEG-DLSSP-------------------------------------------EASPQTAKPTAVPPVKESDDKPTEHYYRLLWFKVKKMPLTEYLKRIKLP-----------------------NSIDSYTDRLYLLWLLLVTLAYNWNCCFIPLRLVFPYQTADNIHYWLIADIICDIIYLYDMLFIQPRLQFVRGGDIIVDSNELRKHYRTSTKFQLDVASIIPFDICYLFFG-FNPMFRANRMLKYTSFFEFNHHLESIMDKAYIYRVIRTTGYLLFILHINACVYYWASNYEGIGTTRWVYDGEGNEYLRCYYWAVRTLITIGGLPEPQTLFEIVFQLLNFFSGVFVFSSLIGQMRDVIGAATANQNYFRACMDDTIAYMNNYSIPKLVQKRVRTWYEYTWDSQRMLDESDLLKTLPTTVQLALAIDVNFSIISKVDLFKGCDTQMIYDMLLRLKSVLYLPGDFVCKKGEIGKEMYIIKHGEVQVLGGPDGTKVLVTLKAGSVFGEISLLAAG--GGNRRTANVVAHGFANLLTLDKKTLQEILVHYPDSERILMKKARVLLKQKAKTAEATPP--RKDLALLFPPKEETPKLFKTL--LGGTGKASLARLLKLKREQAAQKKENSEGGEEEGKENEDKQKENEDKQKENEDKGKENEDKDKGREPEEKPLDRPECTASPIAVEEEPHSVRRTVLPRGTSRQSLIISMAPSAEGGEEVLTIEVKEKAKQ-----------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AB32TKR5-1", "uniprot_id": "A0AB32TKR5_DANRE", "id": "A0AB32TKR5-1", "name": "", "aln": "------------------------------------------MFSTLKTIFWPRAAVAVAQSPGPPASTTTTPPVKQE---------------------------------------------------EKPEPKKDEEKKEEKKEEQKPTETAPASAPAPAPGSAPAPAPAPAPGSAPAPAPA-------------------------------------------------------------SAPAPAPASAPAPAPASAPAPAPASAPAPASAPAPDPPKPADPANPGAETAGEDGPPSPPTPPVVYYRYTDDQLRDIVKKMRERTELYKDKIVDPYASSPERTPPVTPVYRKED-----------------WIRKQEEERIKREEAEQKKKEDDAKRAAAKKEKEEKEKKEKEEKLKAEKEAADKEAAEAMFPKIKCTCIDTLLKPFEDKMDSYLGATIDPFTDRRYIKWLSVVTVAFNYNVWLATARLCFPYHTPATIPFWILFDFLADLVNVIDITMFQPRLQFVKAGDIIKDRVQTKQNYRESARFQTDLISIIPFDLLCFQFG-FTSFFRLNRFMRYQSFFEFSDRLESIMAKAYIWRVGRTTGYLLYCLHINSCLYYVASEYEGLGSSRWTYDGLGNAYLRCYYFATRTLITIGGLPEPHTLFEIVFQLVNFFTGVFVFSSLIGQMRDVIGAATAGQTYFRASMDSCVAYMNTYTIPKLVQSRVRTWYNYTWDSQGMLDESELLDKMPLVMRTAIAVDINLATFQKIDLFKGCDNQMLVDMLLRLKSIVYLPGDFVCKKGDIGREMYIIKAGEVQVIGGPDNKIVFVTLKAGCVFGEISLLQSAKDGGNRRTANVAAHGFANLFVLDKKDLNDILIHYPESQKVLAKKGRKLMKAKGKAAPTKDEGEKKKGLALFGPKPPTPKMLRAFGGFGKGGLLDKLKVCVDLFRGLMVKQDGSACGLAAGLDCGNFEQIKTAMKRSEVMPFLYPAGSSSGKKELKRSISPFICQSIHPPLHNPSIALSIYPYINPSIHPSIYLSIYLSIYLSIYLSIYLSIYLSIYLSIYLSVCLSVCLSVCLSVYLSVYLSIYLSVYLSVYLSLCLSVYAFIHPYHPSVLHFILYTIHDIFHPSIRSISSSVYPSTTLFTHNTQ", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9W2D5-1", "uniprot_id": "Q9W2D5_DROME", "id": "Q9W2D5-1", "name": "", "aln": "MTSMARFRKVNRQSEKLEPEASASLLKSSPNILENFAYDEFQPIQTNHPLLKRMATTPVAQSGSQSSSSSTSSTRKAEPKFCDTLERHAFMRNVINQQPESTRRYSTPGEKEAQVRRSLEEITKDLKEIEQFVSATEELMQREKEQEQMMYSNKENKCPSPVKRVTYKINAYKAPPRRHRPGSPRFYHSRLYFRNGKIGCVDSTEHQNNVGATHALVKHILHHEKPLVSPDSVRRVLEQDSFEMVPLPGAVPEIVPDPIAIQRAEELAAATGQVVLPKEEEEEEKSSPLHQVESQPDVD--EDEQDVQICYNESPELQNEDRNERTQRTPSINESEIVAVDEPDTEMNSDVDHRKPSSAGSLDSQGQQFLRDQVRHLVRRFTARANKVKSRIELPPTPSSSSTVSSPSPPPTKSLHPSPQHKVRLVPAGQSPHRGRLFEADTPRSNVWLCSSLCG--ANNDERTLDPQGKIYISWLCVVSLSFLYNAWVIPLRASFPFQTKENTNIWLACDFCADIIYLLDVVFFKHRVMYLFEGFWVKNKNLTRKNYMRKLQFKLDLLALLPLELLYFKLGTQAVWLRFPRFFKIQSFWEVFRLLDRVISSPHFVRVAKTLTYMLYMIHITAALYYAYSDYQGLGQNRWVFSGKGHPYVRCFAFATKTATSIGKNPKPERQGEYVFMTVAWLMGVFVFALLIGQIRDIISTATRNKHEYRQLEDETLEYMRRLNLSQEVQSRVKMWFQFTWEQQRTLDESNILDALPINLKTDIAISVHIQTLSKVQLFADCEEALLRDLVLKLRAVTFLPGDFVCRKGEVGREMYIVKLGQVQVMGGPSSDVVLATLTEGSVFGEISLLGIN--GADRRTADVRSKGYSNLFVLSKSDLNEVIAYYPTAQAILKKRARQLMRKNAAREREEER-ERARSALQADVVIGNPKTPETAPKLLQTVIQALPFESPAVVLITRGSK--------------RMRRKRQSVQMETIVEPKMEVTGAAETQDQKGLKTGRCSPDLLSSIQQELKSKHKFINLTDSEKALISQSANNSLEDMKVVDL--------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : :* .. .. . * :: . . .. .* . . . . . .. * . . : . : . . . .: : .: :: :. . : : :. . . . . .: * . . : : .: *: ** :*:::: :* . . * ** :* . *: *: .*:: : *: ::: *: :: * : : :::* . :*: *: :::*::: : :* :* *::: **:*. *: :: .:. *: :* *:*: :**.:.:** *:*:*:* .:*.:.* *: *:**: :*.:* :** *:*. * ** : :: *****: ****:**:*.:** .: :: * : **. .:.: .* **: * ::**..* ****::*. :* :: :*:.::: :.*::** .*: :: *::*:*:: :*******:**::*:****:* *:***:***.. *:.**. *.******** *.:****:* ::*::**:.*.*. *:::: :** :: :* *:.: *: :. : .*: .. : . ", "identical_positions": 148, "similar_positions": 229, "identity": "12.77%" }, { "cls_id": "homologset.agr.MGI:1353563", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9QY31-1", "uniprot_id": "SNAI3_MOUSE", "id": "Q9QY31-1", "name": "Zinc finger protein SNAI3", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MPRSFLVKTHSSHRVPNYGKLETLREANGSCSACKELAGSRHLPDEEAPCNPSDPLQPWDSTSAVACISLPLLPNHRETLGVSGPEPQETSWVGPRAAQAPSVTLKDSFT---LPPLLVLPTRWPPILGPD--GALNEHLRAEGTSRVPG-----SFECIHCHRPYHTLAGLARHQQLHCHLPTG----RAFTCRYCDKEYASLGALKMHIRTHTLPCICKVCGKAFSRPWLLQGHIRTHTGEKPYTCSHCSRAFADRSNLRAHLQTHVGTKKYRCAVCPKAFSRMSLLARHEEAGCCPGP-----------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0ABK0LCD7-1", "uniprot_id": "A0ABK0LCD7_RAT", "id": "A0ABK0LCD7-1", "name": "", "aln": "----------------MTPATVPCNREHERQGQVDGQAPAGSV--------RDHDAGQPSPVGQTPPTTRRVPGPRTCPGRGFAAPPRRAPRWLAEVVR------------------------YANEPDPSRTCRLRCPRAPPDATLGVPPQALDSACSREGT-------------------------MPRSFLVKTHSSHRVPNYGKLETLREANGSCSACEELVGSCHLPDKEASSNPSDPLQPWDSTSAIACVSLPLLPHHGETLGTSGPEPQETSLVGPRAGQAPSVTLKDSFN---LPPVLVLPTRWPPILGSD--GALDEHLRAEGTSRVPG-----SFECIHCHRPYQTLAGLARHQQLHCHLPTG----CAFTCRYCDKEYASLGALKMHIRTHTLPCVCKVCGKAFSRPWLLQGHIRTHTGEKPYTCSHCSRAFADRSNLRAHLQTHAGTKKYSSACLLDLFQKGASIGK---------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q3KNW1-1", "uniprot_id": "SNAI3_HUMAN", "id": "Q3KNW1-1", "name": "Zinc finger protein SNAI3", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MPRSFLVKTHSSHRVPNYRRLETQREINGACSACGGLVVPLLPRDKEAPSVPGDLPQPWDRSSAVACISLPLLPRIEEALGASGLDALEVSEVDPRASRAAIVPLKDSLNHLNLPPLLVLPTRWSPTLGPDRHGAPEKLLGAERMPRAPG-----GFECFHCHKPYHTLAGLARHRQLHCHLQVG----RVFTCKYCDKEYTSLGALKMHIRTHTLPCTCKICGKAFSRPWLLQGHVRTHTGEKPYACSHCSRAFADRSNLRAHLQTHSDAKKYRCRRCTKTFSRMSLLARHEESGCCPGP-----------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VJP2-1", "uniprot_id": "Q9VJP2_DROME", "id": "Q9VJP2-1", "name": "", "aln": "MDKLKYSRCPLKKRPIMVEESSPEDHLSHDEGPVDLSVASAAVPMEPHWMAKSEPEPQPVPTELRRRFDAAMNQTKEQLARRIWEETREIARAFPDVFTREEIAKSLARLGYGEFELPPEEEVMEPEPEPEQHLPLRYTRDASPTIIKAEPSDEEQFPLRNYNNNLLKSIAEYEDCMKMQNIKEEIPPIPSPQLFYPPPTPLAEPEDLSVTQRRVLSENMNLQNVARALLSMQHMAPQHAPPPIDMEEDQENQDINQLKIKSSNDLYYQCQQCNKCYATYAGLVKHQQTHAYESTEYKIIRSQPGGSGAIVDQTEFCTDQASALIQAANVASAQSMQKPVGVPRYHCQDCGKSYSTYSGLSKHQQFHCPSAEGNQVKKVFSCKNCDKTYVSLGALKMHIRTHTLPCKCPICGKAFSRPWLLQGHIRTHTGEKPFSCQHCNRAFADRSNLRAHMQTHSDVKKYSCPTCTKSFSRMSLLAKHLQSGCQTEQSGGPSGSGGGFDQQQLQQHLQVYEEGHNPHQLYYAGSVGSSNGEEEEGGEYQMQPPAIY", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :* . *. . .: . * *. . :. . :. *. . : : . .* : . . : .: .. : . . . . . * . . : .* .* : . :.* .* :.* * :**::*:*:** * .*:*: *** *.**************** * :**************:********::*.**.************:*** ..*** . . *.: : :.: ", "identical_positions": 87, "similar_positions": 72, "identity": "15.88%" }, { "cls_id": "homologset.agr.MGI:1353568", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q68G38-1", "uniprot_id": "TOR1A_RAT", "id": "Q68G38-1", "name": "Torsin-1A", "aln": "----MKLGRATLALLLLVPCVVRAVEPISLGLALAGVLTGYISYPRLYCLFAECCGQKRSLSR-EALQKDLDNKLFGQHLAKRVILNAVSGFLSN-PKPKKPLTLSLHGWTGTGKNFASKIIAENIYEGGLNSDYVHLFVATLHFPHASNITLYKDQLQMWIRGNVSACARSIFIFDEMDKMHAGLIDAIKPFLDYYDVVDEVSYQKAIFIFLSNAGAERITDVALDFWRSGKQREEIKLRDMEHALAVSVFNNKNSGFWHSSLIDRNLIDYFVPFLPLEYKHLKMCIRVEMQSRGYE----EDEDIINKVAEEMTFFPKEEKVFSDKGCKTVFTKLDYYLDD", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9ER39-1", "uniprot_id": "TOR1A_MOUSE", "id": "Q9ER39-1", "name": "Torsin-1A", "aln": "----MKLGRAALALLLLAPCVVRAVEPISLSLALAGVLTTYISYPRLYCLFAECCGQMRSLSR-EALQKDLDNKLFGQHLAKKVILNAVSGFLSN-PKPKKPLTLSLHGWTGTGKNFASKIIAENIYEGGLNSDYVHLFVATLHFPHASNITQYKDQLQMWIRGNVSACARSIFIFDEMDKMHAGLIDAIKPFLDYYDVVDEVSYQKAIFIFLSNAGAERITDVALDFWKSGKQREEIKLRDMEPALAVSVFNNKNSGFWHSSLIDRNLIDYFVPFLPLEYKHLKMCIRVEMQSRGYE----VDEDIISKVAEEMTFFPKEEKVFSDKGCKTVFTKLDYYLDD", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O14656-1", "uniprot_id": "TOR1A_HUMAN", "id": "O14656-1", "name": "Torsin-1A", "aln": "----MKLGRAVLGLLLLAPSVVQAVEPISLGLALAGVLTGYI-YPRLYCLFAECCGQKRSLSR-EALQKDLDDNLFGQHLAKKIILNAVFGFINN-PKPKKPLTLSLHGWTGTGKNFVSKIIAENIYEGGLNSDYVHLFVATLHFPHASNITLYKDQLQLWIRGNVSACARSIFIFDEMDKMHAGLIDAIKPFLDYYDLVDGVSYQKAMFIFLSNAGAERITDVALDFWRSGKQREDIKLKDIEHALSVSVFNNKNSGFWHSSLIDRNLIDYFVPFLPLEYKHLKMCIRVEMQSRGYE----IDEDIVSRVAEEMTFFPKEERVFSDKGCKTVFTKLDYYYDD", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "O77277-1", "uniprot_id": "TORS_DROME", "id": "O77277-1", "name": "Torsin-like protein", "aln": "MMSFPRMLSLCLSVLVILPLPLQSVDPLTIGAVGAVALGAYF-KEHTYCRFAECCDDRNIPARIDELERSLERTLIGQHIVRQHIVPALKAHIASGNKSRKPLVISFHGQPGTGKNFVAEQIADAMYLKGSRSNYVTKYLGQADFPKESEVSNYRVKINNAVRDTLRSCPRSLFIFDEVDKMPSGVFDQLTSLVDYNAFVDGTDNTKAIFIFLSNTAGSHIASHLGSVMKNGRLREDTRLSDFEPLLRKAAYN-MDGGMKKTTMIESHVIDHFIPFLPMEKAHVIKCLEAELLRWRRDPKQANNQKIIEDIINSSISYDRTHSLFAISGCKTLEKKVAMAIY-", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :: *.:*:: * :::*:*:::. . * .* *: : ** *****.: . :* : *::.*: .*:***:.:: *: *: ..: . *.:***.:*:** .******.:: **: :* * .*:** ::. .**: *::: *: ::: :*..: :*.**:*****:*** :*::* :..::** .** .. **:******:...:*:. .. :.*: **: :* *:* * :.:* :.*: ::::*: ::**:*:****:* *: *:..*: : ::.*:. : :. : : . :*: .****: .*: ", "identical_positions": 103, "similar_positions": 138, "identity": "30.03%" }, { "cls_id": "homologset.agr.MGI:1353569", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9QY14-1", "uniprot_id": "FOXE3_MOUSE", "id": "Q9QY14-1", "name": "Forkhead box protein E3", "aln": "------MDAQVAFSG-FPALPSLTPSGPQLPTLAGAEPGREPEEVVGG-GDAEPTAVPGPGKRRRR-------------PLQRGKPPYSYIALIAMALAHAPGRRLTLAAIYRFITERFAFYRDSPRKWQNSIRHNLTLNDCFVKVPREPGNP------------------------------------------GKGNYWTLDPAAADMFDNGSFLRRRKRFKRAELP----APPPPPPPFPYAPFPPPP----------------------------APASAPPARLFRLDSLLGLQPEPPGPVAPEPPCCAAPDAA---FPPCAAAASPPLYSPASERLGLPA------PLPAQPLLALAG--------------------------------SAGALGPLGAGEAYLRQPGFAPGLERYL-----------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q63250-1", "uniprot_id": "FOXE3_RAT", "id": "Q63250-1", "name": "Forkhead box protein E3", "aln": "------MDAHVAFSG-FPTLPSVSPSGPQPPSLAGDEPGREPEEVVGG-GDSEPPAAPGPGRRRRR-------------PLQRGKPPYSYIALIAMALAHAPGRRLTLAAIYRFITERFAFYRDSPRKWQNSIRHNLTLNDCFVKVPREPGNP------------------------------------------GKGNYWTLDPAAADMFDNGSFLRRRKRFKRTELP----APPPPP--FPYAPFPPAP----------------------------APAPAPPARLFRLDSLLGLQTEPPGPLAPEPPCCAAPDAS---FPPCAAAASPPLYSPAPERLGLPA------PLPAEPLLALAG--------------------------------SAGALGPLGAGEAYLRQPGFPPGLERYL-----------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q13461-1", "uniprot_id": "FOXE3_HUMAN", "id": "Q13461-1", "name": "Forkhead box protein E3", "aln": "MAGRSDMDPPAAFSG-FPALPAVAPSGPPPSPLAGAEPGREPEEAAAGRGEAAPTPAPGPGRRRRR-------------PLQRGKPPYSYIALIAMALAHAPGRRLTLAAIYRFITERFAFYRDSPRKWQNSIRHNLTLNDCFVKVPREPGNP------------------------------------------GKGNYWTLDPAAADMFDNGSFLRRRKRFKRAELPAHAAAAPGPPLPFPYAPYAPAPGPALLVPP-----------------PSAGPGPSPPARLFSVDSLVNLQPELAGLGAPEPPCCAAPDAAAAAFPPCAAAASPPLYSQVPDRLVLPATRPGPGPLPAEPLLALAG--------------------------------PAAALGPLSPGEAYLRQPGFASGLERYL-----------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P40466-1", "uniprot_id": "FKH1_YEAST", "id": "P40466-1", "name": "Fork head protein homolog 1", "aln": "---MSVTSREQKFSGKYSSYTAQDRQGLVNAVTCVLSSSSDPVAVSSDYSNSLSIAREVNAYAKIAGCDWTYYVQKLEVTIGRNTDSLNLNAVPGTVVKKNIDIDLGPAKIVSRKHAAIRFNLES-GSWELQIFGRNGAKVNFRRIPTGPDSPPTVLQSGCIIDIGGVQMIFILPEQETIISDYCLNHLMPKLLSTYGTNGNNNPLLRNIIEGSTYLREQRLQEEARLQQLDHLHTPLSSSSDVNPIGDPHGDTIMMEEDEEDENYTRGGIRPNTYTSSSNNAVTNGNVPHIENPSDLSLDENRYIKP-PQSYASMITQAILSTPEGSISLADIYKFISDNYAFYRFSQMAWQNSVRHNLSLNKAFEKVPKRAGQQGKGMNWKISDEVRRDFLNKWNAGKLSKIRRGASVTRQLQLHMSKFGEIPAPESSSIDPRGIKAQKVKKSLQATSSILGESAPQLQRTQLTGQISTTTSMDVTTNANVNNSSLS", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . *** :.: .: .* . . ... :* . .. .:: . . . : .: *.. . . *: . .: : . * * * : * :* .*: .* . : * ::* *..* *. . :* ::::..::**.:: :.:.* . . * . . . . ..: ::. .*. : * * . *: : .* .: : . :*. .:. : ... *:* *. *. : * : ** : . : ", "identical_positions": 37, "similar_positions": 104, "identity": "7.57%" }, { "cls_id": "homologset.agr.MGI:1353573", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A2VCW9-1", "uniprot_id": "AASS_RAT", "id": "A2VCW9-1", "name": "Alpha-aminoadipic semialdehyde synthase, mitochondrial", "aln": "MLRAQRLRLARLRACVSRG-------LHHKPVMALRREDVNAWERRAPLAPKHIKGITKLGYKVLIQPSNRRAIHDKEYVRAGGILQEDITEACLILGVKRPPEEKLMSKKTYAFFSHTIKAQEANMSLLDEVLKQEIRLIDYEKMVDHRGSRIVAFGHWAGVAGMINILHGMGLRLLALGHHTPFMHLGMAHNYRNSSQAVQAVRDAGYEISLGLMPKSIGPLTFVFTGTGNVSKGAQEVFNELPCEYVEPHELKEVSKTGDLRKVYGTVLSRHHHLVRKTDGVYDPVEYEKYPERYISRFNADIAPYTTCLINGIYWEQNTPRLLTRQDAQSLLVPVKSSVVPVEG-CPELPHKLVAICDISADTGGSIDFMTECTTIERPFCMYDADQHIIHDSVEGSGILMCSIDNLPAQLPIEATEYFGDMLYPYVEEMLLSDASQPLESQNFSPVVRDAVITSNGLLTDKYKYIQKLRESRERIQFLSMS----TKKKVLVLGSGYVSGPVLEYLSRGNNIEITLGSDMTNQMQQLSKKY-DINTVNVTVGKQEDKLQSLVESQDLVISLLPYVLHPVVAKACIDSKVNMVTASYITPAMKELEKSVDDAGITVIGELGLDPGLDHMLAMETIDKAKDLGATIESYVSYCGGLPAPEHSDNPLRYKFSWSPVGVLMNIMQPASYLLNGKVVNVTGGVSFLNSVTPMDYFPGLNLEGYPNRDSTKYAEIYGIS-SAHTLLRGTLRYKGYSKALNGFVKLGLINRETYPALRPEANPLTWKQLLCDLVGISRSSSCEKLKEVVFTKLGGDSTQ----LEAAEWLGLLGDEQVPQAESIVDAFSKHLVSKLSYGPEEKDMIVMRDSFGIRHPSGHLENKTIDLVVYGDFNGFSAMAKTVGLPTAMAAKMLLDGEIETKGLMGPFSKEIYGPILERIKAEGIVFNTQSTIKL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q99K67-1", "uniprot_id": "AASS_MOUSE", "id": "Q99K67-1", "name": "Alpha-aminoadipic semialdehyde synthase, mitochondrial", "aln": "MLRAQRPRLARLRACLSRG-------LHHKPVMALRREDVNAWERRAPLAPKHIKGITKLGYKVLIQPSNRRAIHDKEYVRAGGILQEDITEACLILGVKRPPEEKLMSKKTYAFFSHTIKAQEANMNLLDEVLKQEIRLIDYEKMVDHRGSRIVAFGQWAGVAGMINILHGMGLRLLALGHHTPFMHLGMAHNYRNSSQAVQAVRDAGYEISLGLMPKSIGPLTFVFTGTGNVSKGAQEVFNELPCEYVEPHELREVSKTGDLRKVYGTVLSRHHHLVRKTDGVYDPVEYEKYPERYTSRFNTDIAPYTTCLINGIYWEQNTPRLLTRQDAQSLLVPVKSSVVPVEG-CPELPHKLVAICDISADTGGSIDFMTECTTIERPFCMYDADQQIIHDSVEGSGILMCSIDNLPAQLPIEATEYFGDMLYPYVEEMLLSDASQPLESQNFSPVVRDAVITSNGLLTDKYKYIQKLRESRERIQFLSMS----TKKKVLVLGSGYVSGPVLEYLSRDNNIEITLGSDMTNQMQQLSKKY-NINPVSLTVGKQEAKLQSLVESQDLVISLLPYVLHPVVAKACIESRVNMVTASYITPAMKELEKSVDDAGITVIGELGLDPGLDHMLAMETIDTAKELGATVESYVSYCGGLPAPEHSDNPLRYKFSWSPVGVLMNIMQPASYLLNGKVVNVTGGVSFLNSVTPMDYFPGLNLEGYPNRDSIKYAEIYGIS-SAHTLLRGTLRYKGYSKALNGFVKLGLINREAYPALRPEANPLTWKQLLCDLVGISRSSPCEKLKEVVFTKLGGDNTQ----LEAAEWLGLLGDEQVPQAESIVDAFSKHLVSKLSYGPEEKDMIVMRDSFGIRHPSGHLENKTIDLVVYGDFNGFSAMAKTVGLPTAMAAKMLLDGEIEAKGLMGPFTKEIYGPILERIKAEGIVFNTQSTIKL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9UDR5-1", "uniprot_id": "AASS_HUMAN", "id": "Q9UDR5-1", "name": "Alpha-aminoadipic semialdehyde synthase, mitochondrial", "aln": "MLQVHRTGLGRLGVSLSKG-------LHHKAVLAVRREDVNAWERRAPLAPKHIKGITNLGYKVLIQPSNRRAIHDKDYVKAGGILQEDISEACLILGVKRPPEEKLMSRKTYAFFSHTIKAQEANMGLLDEILKQEIRLIDYEKMVDHRGVRVVAFGQWAGVAGMINILHGMGLRLLALGHHTPFMHIGMAHNYRNSSQAVQAVRDAGYEISLGLMPKSIGPLTFVFTGTGNVSKGAQAIFNELPCEYVEPHELKEVSQTGDLRKVYGTVLSRHHHLVRKTDAVYDPAEYDKHPERYISRFNTDIAPYTTCLINGIYWEQNTPRLLTRQDAQSLLAPGKFSPAGVEG-CPALPHKLVAICDISADTGGSIEFMTECTTIEHPFCMYDADQHIIHDSVEGSGILMCSIDNLPAQLPIEATECFGDMLYPYVEEMILSDATQPLESQNFSPVVRDAVITSNGTLPDKYKYIQTLRESRERAQSLSMG----TRRKVLVLGSGYISEPVLEYLSRDGNIEITVGSDMKNQIEQLGKKY-NINPVSMDICKQEEKLGFLVAKQDLVISLLPYVLHPLVAKACITNKVNMVTASYITPALKELEKSVEDAGITIIGELGLDPGLDHMLAMETIDKAKEVGATIESYISYCGGLPAPEHSNNPLRYKFSWSPVGVLMNVMQSATYLLDGKVVNVAGGISFLDAVTSMDFFPGLNLEGYPNRDSTKYAEIYGIS-SAHTLLRGTLRYKGYMKALNGFVKLGLINREALPAFRPEANPLTWKQLLCDLVGISPSSEHDVLKEAVLKKLGGDNTQ----LEAAEWLGLLGDEQVPQAESILDALSKHLVMKLSYGPEEKDMIVMRDSFGIRHPSGHLEHKTIDLVAYGDINGFSAMAKTVGLPTAMAAKMLLDGEIGAKGLMGPFSKEIYGPILERIKAEGIIYTTQSTIKP", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "E7FD66-1", "uniprot_id": "E7FD66_DANRE", "id": "E7FD66-1", "name": "Alpha-aminoadipic semialdehyde synthase, mitochondrial", "aln": "MLRLVRSQGRGFRGCMCCQRRSQHNQQNHKSVIAIRREDVNVWERRAPLAPRHVREITAAGHKVLVQPSNRRAIHDRYYEKAGAVIQEDISEASLIIGVKRPPEEKVYPRKTYAFFSHTIKAQEANMGLLDDLLKKEVRLIDYEKMVDPNGYRIVAFGQWAGVAGMINILHGLGLRFLALGHHTPFMHIGMAHNYRNVSQAIQAVRDCGYEISLGLMPKSIGPLTFVFTGTGNVSKGAQDIFNELPCEFVEPHELKEVSLSGDLTKVYATVISRHHHLMRRSDGLYDPLEYENHPELYTSHFRDTVAPYTTCLINGIYWDPHTPRLLRRLDAQRLIRPVVTTSSSADYGCPALPHKFLAICDISADTGGSIEFMTECTTIEKPFCMYDANQHIDHDSVEGNGILMCSIDNLPAQLPIEATEYFGDRLFPYVMEMLPSDATKPLEEEDFSPQVRDAVITSNGKLTPKFEYIQKLRERRESEQILKKG----GMKRVLLLGAGYVSGPVIEYLTRDAGTQVTVASNLLNQAEEMATRYPNTIAVMLDITSQEGHLESLIKDHDIVISMLPYSFHPQVAKHCIKLKVNMVTASYLSPAMKELQKSAEDAGITIVNEMGLDPGIDHMLAMECIDQAKADGCTVESYSSFCGGLPAPECSDNPLRYKFSWSPYGVLLNTISPAIYLKDNQIVSVPPGGALLDVTKEMDFMPGFNLEGFPNRDSTKYAEPYGIE-SAHTLIRGTLRFRGFSSAMSGFVKLGLINTEPCPLLDHTASPVSWKELLCKQIGLSATVSNSVFEDAVYEKIGKDDFR----MQSLKWLGLLGEEPVPHAETILAAVAKHLEAKLSFDKGERDMIIMRNDVGIRHPTGELETKHISLVVYGDPSGYSAMAKTVGYPAAIAAHMVLNGELTTKGLVVPMVKSIYSPVLKRLQDEGLQFITKSSVSE", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VLX0-1", "uniprot_id": "Q9VLX0_DROME", "id": "Q9VLX0-1", "name": "Alpha-aminoadipic semialdehyde synthase, mitochondrial", "aln": "MWRVIQLR-ATIAHPFTRQ--------RHSRVIAIRREDQSVWERRAPFGPTHVQKLVKQNVKVIVQPSNRRAYPMQAYMQAGAHIQEDISDASVIFGVKQVPIDALIPGKTYCFFSHTIKAQESNMPLLDAILEKKIRLIDYERIIDERGARQVAFGKYAGVAGMVNILHGIGLRLLALGHHTPFMHIGPAHNYRNSSMARQAIRDCGYEISLGMMPKSIGPLTFVFTGSGNVSQGAQEVFSELPIEYVPPEMLRKVAEHGNQNKLYGCEVSRSDHLERREGGGFDAKEYDEFPERYISTFSTKIAPYASVIVNGIYWAVGSPKLISIPDAKNLLRPANTPWLPTSKGSPALPHRMLAICDISADPGGSIEFMNECTTIDTPFCLYDADRNKDTKSFKGPGVLVCSIDNMPTQLPRESTDLFGELLAPHVHDIIKSDAKKPLAEENFSYPIQSAIIASNGQLTEGFQYIQELRESQSHRSRHKMEGSSESDKKVLVLGAGMVSAPLVEWLHREKDVSITVCSQVKEEADRLAQQYAGVDSVYLDVNESTGHLQELCGRADVVVSLLPYSLHGMVARYCVAEGTHMVTASYLNDEISGLHEEAKAKGVTIMNEVGLDPGIDHLLALECIHEVQDKGAVVESFVSYCGGLPAPEHSNNALRYKFSWSPRGVLLNTLSAAKYLSQGQIVEISGGGELMSSPRSLDFLPGFALEGFPNRDSTKYGNLYGLGRDVHTLLRGTIRYKGFSESIKPMQLLGLIDPEPHALLHPSGPDVTWRQLVIHLMGMSDS---TIFYENLKQKLTERIGD----VDGIESLGLLDDTPVVKLNTPLDTLSHYLSKRLAFERDERDLVVLRHEVGIRWPDGRREERGINFVVYGQPQGHSAMAMTVGKPAAIAAKMILDGEIQERGVLLPFTPDIYRPMLQRLRSEGLTATETSRWLN", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P38999-1", "uniprot_id": "LYS9_YEAST", "id": "P38999-1", "name": "Saccharopine dehydrogenase [NADP(+), L-glutamate-forming]", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MG------KNVLLLGSGFVAQPVIDTLAANDDINVTVACRTLANAQALAKPS-GSKAISLDVTDDS-ALDKVLADNDVVISLIPYTFHPNVVKSAIRTKTDVVTSSYISPALRELEPEIVKAGITVMNEIGLDPGIDHLYAVKTIDEVHRAGGKLKSFLSYCGGLPAPEDSDNPLGYKFSWSSRGVLLALRNSAKYWKDGKIETVSSE-DLMATAKPYFIYPGYAFVCYPNRDSTLFKDLYHIP-EAETVIRGTLRYQGFPEFVKALVDMGMLKDDANEIFS---KPIAWNEALKQYLGAKSTSKEDLIASIDSKATWKDDEDRERILSGFAWLGLFSDAKITPRGNALDTLCARLEELMQYEDNERDMVVLQHKFGIEWADGTTETRTSTLVDYGKVGGYSSMAATVGYPVAIATKFVLDGTIKGPGLLAPYSPEINDPIMKELKDKYGIYLKEKTVA-", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :.**:**:* :: *::: * . .:*: . : : :. . .: : : .. * : *:*:*::** :* *.: .: ..:**:**:. : *. . *:*::.*:*****:**: *:: *. .: * ::*: *:******** *:*.* ******. ***: ..* * :.:: :. :: ** : :***** : : * : ...*::***:*::*: . :. : :*::. :. : ::*.: : . :* . : : . :.. ***:.: : . : :.. * : : *:*:::::...**. . * * : :* **. *.*:** *** *.*:*::::*:* : *:: * .* *:::.:: : . ", "identical_positions": 104, "similar_positions": 159, "identity": "11.02%" }, { "cls_id": "homologset.agr.MGI:1353574", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0ABK0M7R6-1", "uniprot_id": "A0ABK0M7R6_RAT", "id": "A0ABK0M7R6-1", "name": "Zinc finger protein 330", "aln": "MPKKKTGARKKAENRREREKQLRASRSTVDLAKHPCNASMECDKCQRRQKNRAFCYFCNSVQKLPICAQCGKTKCMMKSSDCVIKHAGVYSTGLAMVGAICDFCEAWVCHGRKCLSTHACACPLTDAECVECERGVWDHGGRIFSCSFCHNFLCEDDQFEHQASCQVLEAETFKCVSCNRLGQHSCLRCKACFCDEHTRSKVFKQEKGKQPPCPKCGHETQETKDLSMSTRSLKFGRQTGGEEGDGASGYDAYWKNLSSDKYG---DTGYR---DEEEEEEEAEDDEEDDG---KDSDAESSDLFNNLNLGRTYASGYAHYEEQEN", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q922H9-1", "uniprot_id": "ZN330_MOUSE", "id": "Q922H9-1", "name": "Zinc finger protein 330", "aln": "MPKKKTGARKKAENRREREKQLRASRSTVDLAKHPCNASMECDKCQRRQKNRAFCYFCNSVQKLPICAQCGKTKCMMKSSDCVIKHAGVYSTGLAMVGAICDFCEAWVCHGRKCLSTHACACPLTDAECVECERGVWDHGGRIFSCSFCHNFLCEDDQFEHQASCQVLEAETFKCVSCNRLGQHSCLRCKACFCDEHTRSKVFKQEKGKQPPCPKCGHETQETKDLSMSTRSLKFGRQTGGEE-DGASGYDAYWKNLSSDKYG---DTGYH---DDDEEEDEAEDEEEEDG---KDSDAESSDLFNNLNLGRTYASGYAHYEEQES", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9Y3S2-1", "uniprot_id": "ZN330_HUMAN", "id": "Q9Y3S2-1", "name": "Zinc finger protein 330", "aln": "MPKKKTGARKKAENRREREKQLRASRSTIDLAKHPCNASMECDKCQRRQKNRAFCYFCNSVQKLPICAQCGKTKCMMKSSDCVIKHAGVYSTGLAMVGAICDFCEAWVCHGRKCLSTHACACPLTDAECVECERGVWDHGGRIFSCSFCHNFLCEDDQFEHQASCQVLEAETFKCVSCNRLGQHSCLRCKACFCDDHTRSKVFKQEKGKQPPCPKCGHETQETKDLSMSTRSLKFGRQTGGEEGDGASGYDAYWKNLSSDKYG---DTSYH---DEEEDEYEAEDDEEEEDEGRKDSDTESSDLFTNLNLGRTYASGYAHYEEQEN", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VAU9-1", "uniprot_id": "ZN330_DROME", "id": "Q9VAU9-1", "name": "Zinc finger protein 330 homolog", "aln": "MPKKKTGQRKKAEKQKLRLKEIRSR--EVPLADLPCNAPMECDKCEKKQKSRAFCYFCQSIQRLPICAQCGKIKCMLKTGDCVVKHPGVYTTGLGMVGAICDFCEAWVCHGRKCLQNHACTCPLQNATCLECERGVWEHGGRIFKCSFCNGFLCEDDQFEHQASCQVLESENYKCQSCNKLGQYSCLRCKTCYCEDHVRRKGFKYDKNKPIPCPKCNYDTSVTKDLSMSTRSHKFGRQQQGGNSDDEEGYGGYYGAGGSGYYGGAASGGYSYGGDDDEDESDGDYDDESDE---DDDDDEEEDETTESEPEKETDKKATK------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "******* *****::: * *::*: : **. ****.******:::**.*******:*:*:********* ***:*:.***:**.***:***.********************..***:*** :* *:*******:******.****:.******************:*.:** ***:***:******:*:*::*.* * ** :*.* *****.::*. ********** ***** * : *. .**..*: .*. ** . .* *::*:* :.: ::*.: .*.* *..* .: : : . :: ", "identical_positions": 187, "similar_positions": 79, "identity": "57.36%" }, { "cls_id": "homologset.agr.MGI:1353576", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I6AKZ7-1", "uniprot_id": "A0A8I6AKZ7_RAT", "id": "A0A8I6AKZ7-1", "name": "", "aln": "---------------MELEN--YEQPVVLREDNLRRRRRMKPRSAAGSLSSMELIPIEFVLPTSQRISKTPETALLHVAGHGNVEQMKAQVWLRALETSVAAEFYHRLGPDQFLLLYQKKGQWYEIYDRYQVVQTLDCLRYWKMMHKSPGQIHVVQRHVPSEETLAFQKQLTSLIGYDVTDISNVHDDELEFTRRRLVTPRMAEVAGRDAKLYAMHPWVTSKPLPDYLSKKIVNNCIFIVIHRGTTSQTIKVSADDTPDTILQSFFTKMAKKKSLMNIPESQSEQDFVLRVCGRDEYLVGETPLKNFQWVRQCLKNGEEIHLVLDTPPDPALDEVRNEEWPLVDDCTGVTGYHEQLTIHGKDHESVFTVSLWDCDRKFRVKIRGIDIPVLPRNTDLTVFVEANIQHGQQVLCQRRTSPKLFTEEVLWNVWLEFGIKIKDLPKGALLNLQIYCCKTPSLSSKASVETPGSESKGKAQLLYYVNLLLIDHRFLLRHGGYVLHMWQISGKAEEQGSFNADKLTSATNPDKENSMSISILLDNYCHPIALPKHRPTPDPEGDRVRAEMPNQLRKQLEAIIATDPLNPLTAEDKELLWHFRYESLKHPKAYPKLFSSVKWGQQEIVAKTYQLLARREIWDQSALDVGLTMQLLDCNFSDENVRAIAVQKLESLEDDDVLHYLLQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSRHYQQRFAVILEAYLRGCGKAMLQDFTQQVHVIEMLQKVTIDIKSLSAEKYDVSSQVISQLKQKLESLQNSSLPESFRVPYDPGLKAGTLVIEKCKVMASKKKPLWLEFKRADPTVLSNETIGIIFKHGDDLRQDMLILQILRIMESIWEAESLDLCLLPYGCISTGDKIGMIEIVKDATTIAQIQQSTVGNTGAFKDEVLNHWLKEKCPIEEKFQAAVERFVYSCAGYCVATFVLGIGDRHNDNIMISETGNLFHIDFGHILGNYKSFLGINKERVPFVLTPDFLFVMGTSGKKTSPHFQKFQDCCV-----------------YFTILQGCLR--------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9JHG7-1", "uniprot_id": "PK3CG_MOUSE", "id": "Q9JHG7-1", "name": "Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform", "aln": "---------------MELEN--YEQPVVLREDNLRRRRRMKPRSAAGSLSSMELIPIEFVLPTSQRISKTPETALLHVAGHGNVEQMKAQVWLRALETSVAAEFYHRLGPDQFLLLYQKKGQWYEIYDRYQVVQTLDCLHYWKLMHKSPGQIHVVQRHVPSEETLAFQKQLTSLIGYDVTDISNVHDDELEFTRRRLVTPRMAEVAGRDAKLYAMHPWVTSKPLPDYLSKKIANNCIFIVIHRGTTSQTIKVSADDTPGTILQSFFTKMAKKKSLMNISESQSEQDFVLRVCGRDEYLVGETPLKNFQWVRQCLKNGDEIHLVLDTPPDPALDEVRKEEWPLVDDCTGVTGYHEQLTIHGKDHESVFTVSLWDCDRKFRVKIRGIDIPVLPRNTDLTVFVEANIQHGQQVLCQRRTSPKPFAEEVLWNVWLEFGIKIKDLPKGALLNLQIYCCKTPSLSSKASAETPGSESKGKAQLLYYVNLLLIDHRFLLRHGDYVLHMWQISGKAEEQGSFNADKLTSATNPDKENSMSISILLDNYCHPIALPKHRPTPDPEGDRVRAEMPNQLRKQLEAIIATDPLNPLTAEDKELLWHFRYESLKHPKAYPKLFSSVKWGQQEIVAKTYQLLARREIWDQSALDVGLTMQLLDCNFSDENVRAIAVQKLESLEDDDVLHYLLQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSRHYQQRFAVILEAYLRGCGTAMLQDFTQQVHVIEMLQKVTIDIKSLSAEKYDVSSQVISQLKQKLESLQNSNLPESFRVPYDPGLKAGTLVIEKCKVMASKKKPLWLEFKCADPTVLSNETIGIIFKHGDDLRQDMLILQILRIMESIWETESLDLCLLPYGCISTGDKIGMIEIVKDATTIAQIQQSTVGNTGAFKDEVLNHWLKEKCPIEEKFQAAVERFVYSCAGYCVATFVLGIGDRHNDNIMISETGNLFHIDFGHILGNYKSFLGINKERVPFVLTPDFLFVMGSSGKKTSPHFQKFQDVCVRAYLALRHHTNLLIILFSMMLMTGMPQLTSKEDIEYIRDALTVGKSEEDAKKYFLDQIEVCRDKGWTVQFNWFLHLVLGIKQGEKHSA-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P48736-1", "uniprot_id": "PK3CG_HUMAN", "id": "P48736-1", "name": "Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform", "aln": "---------------MELEN--YKQPVVLREDNCRRRRRMKPRSAAASLSSMELIPIEFVLPTSQRKCKSPETALLHVAGHGNVEQMKAQVWLRALETSVAADFYHRLGPHHFLLLYQKKGQWYEIYDKYQVVQTLDCLRYWKATHRSPGQIHLVQRHPPSEESQAFQRQLTALIGYDVTDVSNVHDDELEFTRRGLVTPRMAEVASRDPKLYAMHPWVTSKPLPEYLWKKIANNCIFIVIHRSTTSQTIKVSPDDTPGAILQSFFTKMAKKKSLMDIPESQSEQDFVLRVCGRDEYLVGETPIKNFQWVRHCLKNGEEIHVVLDTPPDPALDEVRKEEWPLVDDCTGVTGYHEQLTIHGKDHESVFTVSLWDCDRKFRVKIRGIDIPVLPRNTDLTVFVEANIQHGQQVLCQRRTSPKPFTEEVLWNVWLEFSIKIKDLPKGALLNLQIYCGKAPALSSKASAESPSSESKGKVQLLYYVNLLLIDHRFLLRRGEYVLHMWQISGKGEDQGSFNADKLTSATNPDKENSMSISILLDNYCHPIALPKHQPTPDPEGDRVRAEMPNQLRKQLEAIIATDPLNPLTAEDKELLWHFRYESLKHPKAYPKLFSSVKWGQQEIVAKTYQLLARREVWDQSALDVGLTMQLLDCNFSDENVRAIAVQKLESLEDDDVLHYLLQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSRHYQQRFAVILEAYLRGCGTAMLHDFTQQVQVIEMLQKVTLDIKSLSAEKYDVSSQVISQLKQKLENLQNSQLPESFRVPYDPGLKAGALAIEKCKVMASKKKPLWLEFKCADPTALSNETIGIIFKHGDDLRQDMLILQILRIMESIWETESLDLCLLPYGCISTGDKIGMIEIVKDATTIAKIQQSTVGNTGAFKDEVLNHWLKEKSPTEEKFQAAVERFVYSCAGYCVATFVLGIGDRHNDNIMITETGNLFHIDFGHILGNYKSFLGINKERVPFVLTPDFLFVMGTSGKKTSPHFQKFQDICVKAYLALRHHTNLLIILFSMMLMTGMPQLTSKEDIEYIRDALTVGKNEEDAKKYFLDQIEVCRDKGWTVQFNWFLHLVLGIKQGEKHSA-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9Q5U7-1", "uniprot_id": "A0A8M9Q5U7_DANRE", "id": "A0A8M9Q5U7-1", "name": "Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform", "aln": "MTDKGGATAGFNTLVMEQQASDDEPPVVRREENKRRRRRMKAFTSASAVS-MEHIAVEFVLPTTNKNSKTLDTLQLDVTGNWTVEQVKVQLWHRAVTSKLCPEFYQKYSPDYCILLYQKKGNWYEIYDKQQVFQTLDCIRYWKALRKDVGKIHLVVRQQPAEDSLQYQRFLNHLIGYDVTDVSNVHDDELEFTRRKLLTPRKIELSDRDPNLYSMDPWMTTTPMPEYLLSKISNNHILMVIHKETTSQTIKVSIDDTPVQVLQSFFAKITNKRALLGISEDVSESDFVLRVCGREEYLYGNNAIKDFHWIRQCLKNGEEIHLVLEHPPNPEQDVVQKEDWSQVDDCTGVAGTHEQLTITEKDHEKVFTISLWDCNRKFRVKILGIDIPVLPRNSELIVFVEASIFHGQQLLAQERTSSKPFTEEVIWNTWLEFNIKIKDLPKGARLSLQVSCGKAQTQTSKET------ECKNKSRLLYYVNLLLVDHRSLLRQGEFILHMWKMPEKSEDNSSVNADKLTSATNPDKNNSMAVAILLDKYCYPVALPKSKDSPDIEGERGQREMPNHLRKQFEQIIATDPLHPLTSEDKELLWHFRQECMRDPKAYPKFLSSVKWGKQEAVAITHYLLERSTIWDRSVLDVGLVLQLLDCHFSDENVRTIAVRKLETLGDDDVLRYLLQLVQAVKFEPYHDSALARFLLKRALRSKRIGHFLFWFLRSEIAQSMHYQQRYAVILEAYLRGCGEEMLQDFRKQVEITEALQKVAREIKQISAEKYDISAQVVFQLRQKLEGLQVLGLPDSFKVPYDPGLRAGALVIEQCKVMASKKKPLWLQFKRADPTTLSSDTIGIIFKDGDDLRQDMLILQILLIMESIWELESLDLSLLPYGCISTGNKIGMIEIVKDATTIANIQQSTVGNTGAFKDEILSQWLREKCVNEDKHQQAVDRFVFSCGGYCVATYVLGIGDRHNDNIMITETGNLFHIDFGHILGNYKSFLGISKERVPFVLTPDFLYLMGTTGKKSSPNFLQFQNVCLKAYLALRHHTNLLIILFSMMLMTGMPQLTSKEDIEYIREALTVGRSEDEAKQHFLDQIEICRDKGWTVQFNWFLHLVLGIKQGVEKRSA", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ** : : *** **:* *******. ::*.::* ** *.:******::: .*: :* *.*:*: .***:*.*:* **: :.:..:**:: .*. :*******:******: **.*****::*** ::. *:**:* *: *:*:: :*: *. ********:************* *:*** *::.**.:**:*.**:*:.*:*:** .** ** *::***: ********* **** :*****:*:::*::*:.*.*. **.*********:*** *:..:*:*:*:*:*****:***:**: **:* * *::*:*. *******:* ****** ****.***:*****:******* **********::* *****.* ****:*.*.***.* *:***:**.****.********** *.**: * *: : :** : *.*.* :*********:*** ***:* ::****::. *.*::.*.*************:***:::****:**:*:**** : :** **:* : ****:****:* *******:***:********** *.::.******::******:** ** *: ** * :**:*.*****.:*****:*******:***:***:* *****:**************************.**.****************** *****:************ **:** :**.: * ****: :**.:******:*:**: **:****.** **:**:*******:**:*.**:*************:** ****.**.:*******.************** ******* *****.**********:***************:***************:*.:**:**. *:*.* **:***:**.******:**************:***********************.*************::**::***:**:* :**: *: : :: * : ", "identical_positions": 692, "similar_positions": 225, "identity": "61.79%" }, { "cls_id": "homologset.agr.MGI:1353578", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9CQJ7-1", "uniprot_id": "PTTG1_MOUSE", "id": "Q9CQJ7-1", "name": "Securin", "aln": "MATLIFVDKDNEEPGRRLASKDGLKLGTG--VKALDGKLQVSTPRVGKVFNAP-AVPKASRKALGTVNRVAEKPMKTGKPLQPKQPTLTGKKITEKSTKTQSSVPAPDDAYPEIEKFFPFNPLDFESFDLPEEHQISLLPLNGVPLMTLNEERGLEKLLHLGPP-SPLKTPFLSWESDPLYSPPSALSTL-DVELPPVCYDADI", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P97613-1", "uniprot_id": "PTTG1_RAT", "id": "P97613-1", "name": "Securin", "aln": "MATLIFVDKDNEEPGSRLASKDGLKLGSG--VKALDGKLQVSTPRVGKVFGAP-GLPKASRKALGTVNRVTEKPVKSSKPLQSKQPTLSVKKITEKSTKTQGSAPAPDDAYPEIEKFFPFDPLDFESFDLPEEHQISLLPLNGVPLMILNEERGLEKLLHLDPP-SPLQKPFLPWESDPLPSPPSALSAL-DVELPPVCYDADI", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O95997-1", "uniprot_id": "PTTG1_HUMAN", "id": "O95997-1", "name": "Securin", "aln": "MATLIYVDKENGEPGTRVVAKDGLKLGSGPSIKALDGRSQVSTPRFGKTFDAPPALPKATRKALGTVNRATEKSVKTKGPLKQKQPSFSAKKMTEKTVKAKSSVPASDDAYPEIEKFFPFNPLDFESFDLPEEHQIAHLPLSGVPLMILDEERELEKLFQLGPP-SPVKMPSPPWESNLLQSPSSILSTL-DVELPPVCCDIDI", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9NZH5-1", "uniprot_id": "PTTG2_HUMAN", "id": "Q9NZH5-1", "name": "Securin-2", "aln": "MATLIYVDKEIGEPGTRVAAKDVLKLESRPSIKALDGISQVLTRRFGKTYDAPSALPKATRKALGTVNRATEKSVKTNGPRKQKQPSFSAKKMTEKTVKTKSSVPASDDAYPEIEKFFPFNLLDFESFDLPEERQIAHLPLSGVPLMILDEEGELEKLFQLGPP-SPVKMPSPPWECNLLQSPSSILSTL-DVELPAVCYDIDI", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9NZH4-1", "uniprot_id": "PTTG3_HUMAN", "id": "Q9NZH4-1", "name": "Putative pituitary tumor-transforming gene 3 protein", "aln": "MATLIYVDKENEEPGILVATKDGLKLGSGPSIKALDGRSQVSISCFGKTFDAPTSLPKATRKALGTVNRATEKSVKTNGPLKQKQPSFSAKKMTEKTVKAKNSVPASDDGYPEIEKLFPFNPLGFESFDLPEEHQIAHLPLSEVPLMILDEERELEKLFQLGPP-SPLKMPSPPWKSNLLQSPLSILLTL-DVELPPVCSDIDI", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "B8A4J0-1", "uniprot_id": "B8A4J0_DANRE", "id": "B8A4J0-1", "name": "Securin", "aln": "METMIYMDQENGRLMTPAIKSRQNRLHSAP------DQCLRTPLNGKAHLGAP---LQSSRKALGVINKIVNQTSSHEAEEKTKP----------AEAKCKVPTPLPTEELPEIEKFFPYNPSEFECYSVPDEVYLSRFSLAGLGKQTWLPASPVEEFIEPCLPLSPLKMPKEVEYGDEVEAFLQTINELTEVDLPPECDF---", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* *:*::*:: . . :* : . .** :::*****.:*: .::. . : * .* : ..* . : *****:**:: **.:.:*:* :: :.* : :*:::. * **:: * : : : . : * :*:**. * ", "identical_positions": 38, "similar_positions": 57, "identity": "18.63%" }, { "cls_id": "homologset.agr.MGI:1353582", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9QY15-1", "uniprot_id": "DDX25_MOUSE", "id": "Q9QY15-1", "name": "ATP-dependent RNA helicase DDX25", "aln": "MASLLWGGDAGAAESERLNSHFSNLVHPRKNLRGIRSTTVPNIDGSLNTEDDDDDEDDVVDLAANSLLNKLIRQSLIESSHRVEVLQKDPSSPLYSVKTFEELRLKEELLKGIYAMGFNRPSKIQEMALPMMLAHPPQNLIAQSQSGTGKTAAFVLAMLSRVNALELFPQCLCLAPTYELALQTGRVVERMGKFCVDVEVMYAIRGNRIPRGTEVTKQIIIGTPGTVLDWCFKRKLIDLTKIRVFVLDEADVMIDTQGFSDQSIRIQRALPSECQMLLFSATFEDSVWQFAERIIPDPNVIKLRKEELTLNNIRQYYVLCENRKGKYQALCNIYGGITIGQAIIFCQTRRNAKWLTVEMMQDGHQVSLLSGELTVEQRASIIQRFRDGKEKVLITTNVCARGIDVKQVTIVVNFDLPVNQSEEPDYETYLHRIGRTGRFGKKGLAFNMI-EVDKLPLLMKIQDHFNSNIKQLD------PEDMDEIEKIEY----------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9QY16-1", "uniprot_id": "DDX25_RAT", "id": "Q9QY16-1", "name": "ATP-dependent RNA helicase DDX25", "aln": "MASLLWGGDAGAAESERLNSHFSNLVHPRKNLRGIRSTTVPNIDGSLNTEEDDD-EDDVVDLAANSLLNKLIRQSLVESSHRVEVLQKDPSSPLYSVKTFEELRLKEELLKGIYAMGFNRPSKIQEMALPMMLAHPPQNLIAQSQSGTGKTAAFVLAMLNRVNALELFPQCLCLAPTYELALQTGRVVERMGKFCVDVEVMYAIRGNRIPRGTDVTKQIVIGTPGTVLDWCFKRKLIDLTKIRVFVLDEADVMIDTQGFSDQSIRIQRALPSECQMLLFSATFEDSVWQFAERIIPDPNVIKLRKEELTLNNIRQYYVLCENRKDKYQALCNIYGGITIGQAIIFCQTRRNAKWLTVEMMQDGHQVSLLSGELTVEQRASIIQRFRDGKEKVLITTNVCARGIDVKQVTIVVNFDLPVNQSEEPDYETYLHRIGRTGRFGKKGLAFNMI-EVDKLPLLMKIQDHFNSSIKQLD------PEDMDEIEKIEY----------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9UHL0-1", "uniprot_id": "DDX25_HUMAN", "id": "Q9UHL0-1", "name": "ATP-dependent RNA helicase DDX25", "aln": "MASLLWGGDAGAAESERLNSHFSNLSQPRKNLWGIKSTAVRNIDGSINNINEDD-EEDVVDLAANSLLNKLIHQSLVESSHRVEVLQKDPSSPLYSVKTFEELRLKEELLKGIYAMGFNRPSKIQEMALPMMLAHPPQNLIAQSQSGTGKTAAFVLAMLSRVNALELFPQCLCLAPTYELALQTGRVVEQMGKFCVDVQVMYAIRGNRIPRGTDITKQIIIGTPGTVLDWCFKLKLIDLTKIRVFVLDEADVMIDTQGFSDHSIRIQRALPSECQMLLFSATFEDSVWHFAERIIPDPNVIKLRKEELTLNNIRQYYVLCEHRKDKYQALCNIYGSITIGQAIIFCQTRRNAKWLTVEMIQDGHQVSLLSGELTVEQRASIIQRFRDGKEKVLITTNVCARGIDVKQVTIVVNFDLPVKQGEEPDYETYLHRIGRTGRFGKKGLAFNMI-EVDELPSLMKIQDHFNSSIKQLN------AEDMDEIEKIDY----------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "O61305-2", "uniprot_id": "DDX19_DROME", "id": "O61305-2", "name": "DEAD-box helicase Dbp80", "aln": "-----MGDWAKKAEDQEVSKLVDKLN--------------------LDSKSGEETDFDVADPAETSLLIKILGKGLVNTKLSLDIQQKNPNSPLHSVKTFEALHLKASLLKGIYAMGFNTPSKIQETALPTLLADPPQNMIAQSQSGTGKTAAFVLAMLSRVNVCLNHPQVLCLSPTYELAIQTGEVAARMGQFCREIKLRFAVRGEEVDRSKKIEEHILIGTPGKLLDWGIKFRLFDMKKISVFVLDEADVMIATQGHHDQCIRIHKMLNPHCQMLFFSATYGKEVMDFARLIVADPTIIRLMREEESLENIKQYYVKCKNEEGKYNAIQNIYGCISVGQAIIFCHTKRTAAWLAAKMTSDGHSVAVLTGDLTVVQRLDVLDRFRSGLEKVLITTNILSRGIDIEQVTIVVNFDLPVDLDGMADCETYLHRIGRTGRFEPSALTRNSP-IFGVKAESGKIGKEINRSSSGAESGSREMPKEKENISLLKFFSLTGNLDEAWDVQSE", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P20449-1", "uniprot_id": "DBP5_YEAST", "id": "P20449-1", "name": "ATP-dependent RNA helicase DBP5", "aln": "-----MSDTKRDPADLLASLKIDNEKEDTSEVS-TKETVKSQPEKTADSIKPAEKLVPKVEEKKTKQEDSNLISSEYEVKVKLADIQADPNSPLYSAKSFDELGLAPELLKGIYAMKFQKPSKIQERALPLLLHNPPRNMIAQSQSGTGKTAAFSLTMLTRVNPEDASPQAICLAPSRELARQTLEVVQEMGKFTKITSQLIVP--DSFEKNKQINAQVIVGTPGTVLDL-MRRKLMQLQKIKIFVLDEADNMLDQQGLGDQCIRVKRFLPKDTQLVLFSATFADAVRQYAKKIVPNANTLELQTNEVNVDAIKQLYMDCKNEADKFDVLTELYGLMTIGSSIIFVATKKTANVLYGKLKSEGHEVSILHGDLQTQERDRLIDDFREGRSKVLITTNVLARGIDIPTVSMVVNYDLPTLANGQADPATYIHRIGRTGRFGRKGVAISFVHDKNSFNILSAIQKYFGDIEMTRVP-----TDDWDEVEKIVKKVLKD-----------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .. . . . ..: :. . : .: .. . : .. : . : * :*.***:*.*:*: * * .******** *: ****** *** :* .**:*:************** *:**.*** ** :**:*: *** ** .*. .**:* . . : . :...: ::::****.:** :: :*::: ** :******* *: ** *:.**::: * . *:::****: . * .:*. *:.:.. :.* :* .:: *:* *: *::. .*::.: ::** :::*.:*** *::.* * :: .:**.*::* *:* . :* ::: **.* .*******: :****: *::***:***. . .* **:********* ..:: . . * . :. ..: :::. : ", "identical_positions": 154, "similar_positions": 154, "identity": "30.37%" }, { "cls_id": "homologset.agr.MGI:1353586", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0ABK0LP56-1", "uniprot_id": "A0ABK0LP56_RAT", "id": "A0ABK0LP56-1", "name": "", "aln": "--------------------------------------------MEGMEDAEADCS---VAFAEAQR-----WVEAVTEKNFETRDFRASLENGVLLCDLINKLKPGVVRKINRLSTPIAGLDNINVFLKACEQIGLKEAQLFHPGDLQDLSNRVTVKQEETDRRLKNVLITLYWLGRKAQNNPYYHGPYLNLKAFETLLGQALTKALEDSSCLKRSGRDSGYGDIWCPDRGDFPAPPG-SHRREDSFESLDSLGSRSLTSCSSDLTLRGGREGCESDNDWEFTFKMQDYNKDDMSYRRISAIEPKSALPFNRFLPNKSKQPSYVPAPLRKKRPDKNEDNRRSWASPVYTETEGTFSSTQRRAWGPKMENWH-------------------------------------------------------------------------------TVQETSTSSWCLE-----------------EEEEKVTRLPNVVKDDLYVRKLSPVMPSPGS--SFDQFLPKGWTP-EDMNWKKIKR-ETYKPWYKEFQGLSQ-------------FLLLQALQTYS----------------------DDILSSETN--------------------VKLDPTSGPRLITRRKNFSPTPGYRAHDLEPQS-LDPDLENDDFFVRKTRAFHAN-PCVLRAFEDFRRFSEPDDAVERDIILQCREGELVLPDLEKDDMIVRRIPAQKKEVPLSGAPDRYQPVPFPEPWTLPPEIQAKFLSVLERTCPPKDKPSSCRVLVPSHRLKKDDMLTRKIQSWK-LGTAVPPISFRPGPCSEADLRKWEAIREASRLRHRKRLMVERLFQKIYGENGSKSLSDVSAEDVQS-LRQLRYEEMQKIKSQLKEQDQKWQDDLAKWKDRRKSYTSDLQKKKEEREEIEKQALEKSDRSSKTFREMLQDRESQS--STTTSRRRIYS---SDDILDDGVLPPTVTLSETSYQSERLEDKARAHPAEMPKEDSTTFASREDGIAAEIPLASHIPEERRQAPWPSAETRQASSSSAESHQASLPSTESDQARLPSAEPHQASFSSAEPRQVPLVSAEPHQASSFSSTEPHQASLSSALQRPSSLSSSQQSWSTRGEST---RISASLPRSYQRSD-TARLTSVVTARPFGTSSRGISSLPRSYTMDDGWK-YNGDVEVVKREQHDSGRAAGMK-PDSSHFILGSSSEKEVATG-EDVASLSSFVLPSSSSLSHDQAASSKATFSSTSGLDSVSDSGEGRSSSLREVSRSPDQFSDMRISINQTPGTKHDFGFTIKWDVSGISVASVEKGSPAEFSQLQVDDEILAINNTKFSYKDTKKWEEAMANAQETGNLVMDVRRYGKSGS-----------------------PETKWIDTTSGIYSTEKSSSLSVTTDFSESLQSPYSESKEINGIHEESNAFDSKASESISLKNLKRRSQFFEQ--------------GSSDSVAPDLPVPTLSAP-SRWAWDQEEERRRQERWQKEQDRLLQEKYQREQEKLREEWQRAQQEAERENSKYLDEELMVLNSNSISLTSR--ESVTASWEPSWSEGSKSLDREGTRAGDEDRGQLEDDAVYEDQSQKLQERLMLEHEKKRKEQEAQEEELRKQR------EAEAQARAEAEAQARAEAQARAEAQAQAEAEARKR-AEAQKLQAERERETS---VKIY---QYRRPIDSYDLPKREEESSGLLP-------------------------IDRSKSRSTTELNDPLIEKSGSSKYSDRIGTTSFSQRSSKKDQGPSEAELERQQILQEMRKKTSLHNDNSWIRQRSASVN-KEPICLTGIMRRGESLDNLDSQRPGSWRQSSWHSQPAGVYASSSVQDFSRLPPQLLSTSNRAYMRNPSSAVPPL-AGSVKTSPG------SPSPRSHSPSMSQSGSQLRNRSVSGKRVCSYCNSILGKGAAMIIETLGLCYHLHCFKCVSCERDLG-GSSSGAEVRIRNHQLYCNDCYLRFKSGRPTAM", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0AAQ4VMW3-1", "uniprot_id": "A0AAQ4VMW3_MOUSE", "id": "A0AAQ4VMW3-1", "name": "", "aln": "--------------------------------------------MEGMEDAEADCS---VAFAEAQR-----WVEAVTEKNFETTDFRASLENGVLLCDLINKLKPGVVKKINRLSTPIAGLDNINVFLRACEQIGLKEAQLFHPGDLQDLSNRVTVKQEETDRRLKNVLITLYWLGRKAQSNPYYNGPYLNLKAFETLLGQALTKALEDSSCLKRSGRDSGYGDIWCPDRGEFPAPPG-SHRREDSFESLDSLGSRSLTSCSSDFTLRVGKEGCESDIDWEFTFKMQDYNKDDMSYRRISAIEPKSALPFNRFLPNKSKQPSYVPAPLRKKRPDKHEDNRRSWASPVYTETDGTFSSTQRRTWGPKMETWH-------------------------------------------------------------------------------TVQETSTSSWCVE-----------------EEEEKLTRMPNIVKDDLYVRKLSPVMPSPGS--SFDQFLPKCWTP-EDMNWKKIKR-ETYKPWYKEFQGFSQ-------------FLLLQALQTYS----------------------DDILSSETS--------------------VKLDPTSGPRLITRRKNRSPAPGYRAHDLELPA-LDPDLENDDFFVRKTGAFHAN-PCVLRAFEDFRSFSEPDDAVERDIILQCREGELVLPDLEKDDMIVRRIPAQKKEVPLSGAPDRYQPVPFPEPWTLPPEIQAKFLSVLERTRPPKEQSSGCRVLVPSYRQKKDDMLARKIQSWK-LGTAVPPISFKPGPCSEADLQKWEAIWEASRLRHRKRLMVERLFQKIYGENGSKSMSDVSAEDVQN-LRQVRYEEMQKIKSQLKEQDQKWQDDLAKWKNRRKSYTSDLQKKKEEREEIEKQALEKSDRSSKTFREMLQDRESRG--STVTSWRRTYS---SDDILDDGVLPPTVTLSETSYQSERLEDEARAHPAEMPKEDSTTFANREDSVVAETQLASHSPEEQRLAPSPSEEPRQASGSSAEPHQAPLLSTE--------------------PRRTPLPSEE-----------PHQASLSSTLQRPSSLSS-QQSWSTRAEST---RISASLPRSYQRTD-TARLTSVVTARPFGTSSRGISSLPRSYTMDDGWK-YNGDVEVVKREQLDLGRATGPK-PDSSHFISGSASEKEVIAT-EDVASLSSPTLPSSS-LSHDRAVSSKATFSSMSGLDSVSDSGEGRGSPLREVSRSLDQFSDMRVSINQTPGNKPVFGFTIKWDISGIFVASVEQGSPAEFSQLQVDDEILAINNTKFSYKDTKKWEEVMANAQETGNLVMDVRRYGKSGS-----------------------SETKWIDTTSGIYNSDKSSSLSVTTDFSESLQSPYTESKEVNGIHEESNPFDSKASESISLKNLKRRSQFFEQGWPGFSYSSWVYLCGSSDSVAPDLPVPTLSAP-SRWAWDQEEERRRQERWQKEQDRLLQEKYQREQEKLREEWQRAQQEAERENSKYLDEELMVLNSNSISLTSR--EPVAATWEATWSEGSKSLDSEGTRAGEEDRGQLEDDAVYEDQSQKLQE---LEQEKKRKEQEAQEEERRKQREAQAWAEAEAKAWAEAQARAEAEAKARAEAQARAEAEAQKR-AEAQKLQAERERETS---VKIY---QYRRPIDSYDLPKREDDTSGMLP-------------------------TDRSKSRSTTELNDPLIEKNGSSKYSERIGATSFSHRSSKKDQAPSEAELERQQILQEMRKRTSLHNDNSWIRQRSASVN-KEPICLPGIMRRGESLDNLDSQRPGSWRQSPWHSQPAGVYASSSVQDFSRPPPQLLSTSNRAYMRNPSSAVPPP-AGSVKTSPG------SPSPRSHSPSMSQSGSQLRNRSVSGKRVCSYCNNILGKGAAMIIETLGLSYHLHCFKCVSCGCDLG-GSSSGAEVRIRNHQLYCNDCYLRFKSGRPTAM", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8WWI1-1", "uniprot_id": "LMO7_HUMAN", "id": "Q8WWI1-1", "name": "LIM domain only protein 7", "aln": "MKKIRICHIFTFYSWMSYDVLFQRTELGALEIWRQLICAHVCICVGWLYLRDRVCSKKDIILRTEQNSGRTILIKAVTEKNFETKDFRASLENGVLLCDLINKLKPGVIKKINRLSTPIAGLDNINVFLKACEQIGLKEAQLFHPGDLQDLSNRVTVKQEETDRRVKNVLITLYWLGRKAQSNPYYNGPHLNLKAFENLLGQALTKALEDSSFLKRSGRDSGYGDIWCPERGEFLAPPR-HHKREDSFESLDSLGSRSLTSCSSDITLRGGREGFESDTDSEFTFKMQDYNKDDMSYRRISAVEPKTALPFNRFLPNKSRQPSYVPAPLRKKKPDKHEDNRRSWASPVYTEADGTFSSNQRRIWGTNVENWP-------------------------------------------------------------------------------TVQGTSKSSCYLE-----------------EEKAKTRSIPNIVKDDLYVRKLSPVMPNPGN--AFDQFLPKCWTP-EDVNWKRIKR-ETYKPWYKEFQGFSQ-------------FLLLQALQTYS----------------------DDILSSETH--------------------TKIDPTSGPRLITRRKNLSYAPGYRRDDLEMAA-LDPDLENDDFFVRKTGVFHAN-PYVLRAFEDFRKFSEQDDSVERDIILQCREGELVLPDLEKDDMIVRRIPAQKKEVPLSGAPDRYHPVPFPEPWTLPPEIQAKFLCVFERTCPSKEKSNSCRILVPSYRQKKDDMLTRKIQSWK-LGTTVPPISFTPGPCSEADLKRWEAIREASRLRHKKRLMVERLFQKIYGENGSKSMSDVSAEDVQN-LRQLRYEEMQKIKSQLKEQDQKWQDDLAKWKDRRKSYTSDLQKKKEEREEIEKQALEKSKRSSKTFKEMLQDRESQNQKSTVPSRRRMYS---FDDVLEEGKRPPTMTVSEASYQSERVEEKGATYPSEIPKEDSTTFAKREDRVTTEIQLPSQSPVEE--------------------------------------------------------------------------------QSPASLSS-LRSRSTQMEST---RVSASLPRSYRKTD-TVRLTSVVTPRPFGSQTRGISSLPRSYTMDDAWK-YNGDVEDIKRTPNNVVSTPAPS-PDASQLASSLSSQKEVAATEEDVTRLPSPTSPFSS-LSQDQAATSKATLSSTSGLDLMSESGEGEISPQREVSRSQDQFSDMRISINQTPGKSLDFGFTIKWDIPGIFVASVEAGSPAEFSQLQVDDEIIAINNTKFSYNDSKEWEEAMAKAQETGHLVMDVRRYGKAGS-----------------------PETKWIDATSGIYNSEKSSNLSVTTDFSESLQSSNIESKEINGIHDESNAFESKASESISLKNLKRRSQFFEQ--------------GSSDSVVPDLPVPTISAP-SRWVWDQEEERKRQERWQKEQDRLLQEKYQREQEKLREEWQRAKQEAERENSKYLDEELMVLSSNSMSLTTR--EPSLATWEATWSEGSKSSDREGTRAGEEERRQPQEEVVHEDQGKKPQDQLVIERERKWEQQLQEEQE---------------------------------QKRLQAEAEEQKRPAEEQKRQAEIERETS---VRIY---QYRRPVDSYDIPKTEEASSGFLP-------------------------GDRNKSRSTTELDDYSTNKNGNNKYLDQIGNMTSSQRRSKKEQVPSGAELERQQILQEMRKRTPLHNDNSWIRQRSASVN-KEPVSLPGIMRRGESLDNLDSPRSNSWRQPPWLNQPTGFYASSSVQDFSRPPPQLVSTSNRAYMRNPSSSVPPPSAGSVKTSTTGVATTQSPTPRSHSPSASQSGSQLRNRSVSGKRICSYCNNILGKGAAMIIESLGLCYHLHCFKCVACECDLG-GSSSGAEVRIRNHQLYCNDCYLRFKSGRPTAM", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9QJL3-1", "uniprot_id": "A0A8M9QJL3_DANRE", "id": "A0A8M9QJL3-1", "name": "", "aln": "--------------------------------------------MEWRPQSTVDYE---TVYSEAQR-----WIEAVTKKKFGNSNFRSSLENGLLLCDLINKIKPGIIKKLNRFSTPIAGLDNINLFLKACAKLGLKEAQLFHPGDLQDLSTRVTVKHQESSRRLKNVLITIYWLGRKAHADPFYNGPYLKLKAFEGLLGTTLYKALEDCTSLRASVPNRSYPDSWYSEREELFPLRA-GHRREDSLDSLNSLGSRTYS-TSSDATLKGSSEGCGSDPEADLSFTMADNKE----YRRSQVIAPKTTTQFNQFLPSRDKQSGYVPAPLRKKRAERNEDSRRSWASPMFTEDDGTFTSPSPEMAGSDSSSLTGLKSQTAAHQASVYEYESSDSDADRPDPDVVLDDLASRRFHSPSPVAPTNFALPMSPLEATAVPCTTRPHVLISNVPRQTMTHLSSQSQSLQRTYRRPESADVCIYDDSEEEDDEFGYADPVQDDLYARKVG-LMPQLSASVPFDKFLPKFWTPEEDAHINKIKLGSQRRPWYRKIQGFSHKKSGSSSEESDGDVNPWPSVPTFSRTQSEPPRSHSHSPEGLALPSLTSTHSSQTQPLTVAQQIVGLPKFEPPDFWPSPDPSSGPRLIKCEKHPLLGREHPNDPYNVSADILPDLENDDMFTRRTNAFHSSDDLAKLKYGNFLVPRRRSEADVTVVIQPHHEGEPVYPDIEKDDVVSRKVQQQISHRPLSGAPDNYHPVPIPETWALPPKLQAKLMSDPTEPRQSRPK----AELKP--HLKTDDMLLRKLRALNTQGTEGRKAAGVSLSCSEDDMQKWQAIREASRVRYRKRLMVERLFQKNSDSEGSKSVSDITESEMSNSTMELRLEELQKMRNRLKESEDKWQDDLSRWKSKRRSVNSDIVKKKEEREQIEQITSVG-TRKSKTFKEMQDERESRGQSNLRDSFNSIVDDVFEDPVPRSRTLPPRSYTIDTPYTATDKPFVPSIPSLREKEPVAGTLASDQTDLSTKPARASPDIPDKINNSNQMSQTTTQSLLDDPVPAFSNSSTS----------------------LIKPASATKPTSSTKPNISEFISNTKPAESSSDAISSLYKPNSMDTKPSGLDQVSASLPKIYQRSD-SARLTSVVMPRPFGTQSNRIASLPRAFTMDDSVKRTNGESNSLKKTAVQNRYAQYMTDEDKSQQTPDHSSEE------EEVERTQSPVPPVNR---------VSPLPKSTSPLNPPNEVG----------------YNEMRISLNQKPNSSRDFGFQHDWDSTGVRVKSVAPGSPAEFGQVQAGDEILTVNGHRVADMSYSEWKNSMEEALQQGSLLMDIRRQGKNNWGRDLPSLPYKSHKTINLTSLDPLGPSEPYHTTSLDFTSQQSKDAVVKSVNVSSQPAYNHGSNGINGAFRE-DSESVNNKESISLKNLKRRSEFFEQGSAGLTVSSLVYLCGGSETPILNVPVPSITASTTRWSWDPEEERKRQEKWQKEQDRLLKEKYKKDQEKLDEEWKKAQQELNKENFK-NDEELNRHSLSTIRQPTVSWEEQNASKLAQIEEDKKKRQEEMQRLEEERRKREEEMLRLQEERRKQEEQQRLEEEKRKKEEEERKKQIEEKQR-----LEEERRRREEQQRLEELRRKREEEQRLLQEKERNRREEEKKRFQEQDKVDSFCYTNVYPELSYSHRSISKSTPELDEVAKTDIKGVYGRHRGLAGWLLEEELRRKKNPQMQRKQAASELELERRSILNAMKYRNPERASGGLSEVNRDYQKEPLTQSELERQQILQEMRKKTSLNTDNSWIRQSTSSVPAKEPIDLP--IRRGESLDNLDEPRS-SWR-SSWSTSNS----TSSIPDYSRPHSALSGSTLQPAGRPGSATMQASQSMSSLRQST------STPANPPEPRAPQ-----RNRSVSGRKICSFCDTPLGKGAAMIIESLGLCYHLTCFKCSDCRSDLG-GSQAGAEVRIRNQQLYCNVCYMRLKTGQPTAM", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "F6NN15-1", "uniprot_id": "F6NN15_DANRE", "id": "F6NN15-1", "name": "", "aln": "--------------------------------------------MEWRQQSSVSCE---LAFQEAQR-----WIEEVTKKSFGSKSFRVALEDGVLLCDLINTLKPGIIKRLNRLSTPIAGLDNVNVFLKACKKLGLNEAQLFHPGDLQDVSTRVTVRREETNRRLKNVLITIYWLGRKAQSDPFYTGPQLNLKAFEGLLGIALSKALEELAQSRLSVRDSGYSEGWFSDREELYSVKQPSYRREDSVESLDSVESRALS-VASDLTLRAGSEGCCSDAEAEHFFRMAESSK----------------------SGAPIREKAHVPAVLRKKRQDYQQGSR-SYAGHLTSESGHGLCHDLPPAS------------------------------------------------------------------------------------AFLQWASSYQSDS---------------------DSDSDRPEADPEQDDLASRRFRSVTSAAPVN---------FAIP--------------SKPQGPRVTAYVT-------------------------------------------------------------------------------PNAGKSWLT----LSDATRSNQSLSSIPS------ENG-----RTDSDSAN---LEEEFLQRVLSNGTSDSDE----------DRGYADPVLDDLYARRVLVSEHQTSINANSDKF----LPKFWTPEEDLHVRKIRLGSQRRP----------------------WYKKMQGLR--SKSMGDITLEPIPQESDNSSSFDSLGPLHVHQR----------------------SDEELSLDPSALQRVQYEQLQHIRQRMKENEAKWHEDLSRWKSRRRSANSDLHKKLEEREQIELITTAGGASGIRTAHLTGVPEESSSMPGPMSDAGSSVS---SSGWSTSASGLANGATSALTRGTVVETSDSAQKCTGVLSSHPSAVVSEQTSQSSLTAVDAESDEQQ--------------------------------------------------------------------------------GPDFSLRSSLLESFYAGGAR----MSATLPRGFRRSEGCSRLSTGVTPRPFGAKPSKMPTLPKVYSVDDSHKSLISGHRDHSAVPSFLGGQGKVT--ASAGKGHSRSSTHPINPKEEETRDGRSSAPPMNS-YATKVTMTTSIIQTSPPAISEIRDVKVGQ--------------SEMRVCLNQKPNSGRDFGFKAHWDSVGAYVKSVQAGSPAELYGLLMGDEIVALGGRRVDEMNYEQFKSSMETAQQNGTLLMDIRRHGQNDWGSG--------------------QPSLPYQSHKIINLTSATSTLIGRPEHFVPINTSSNSSVETVGKTQVNGQPANGVLSKMMNGSIQDNAAAVRNK-------------GGSESDISDLQVPSISTTSSSWSWDHEEERRRQEKWQMEQERLLQEKYRRDQEKLEEEWRRAQQEVYGEEYCGLEEQKTLDVLSNGNPAPHNSPPFYNQSSATFSVTFN----ENVAAAQNRQACVQTAAGHQS------------------------------------------------------------------IKAEDKCDSPTKTLCSEE---------------------SYGFAKLTVS--------------------------------DRTKSKSTPALEALHKQDAKEG--------------CSKKKGQLSQAEKERLQILDEMRKKTPLHTDSSWIRQRNASIN-KETITVGTSIRRYESMDNLH--TTNSWSRQSYTSGLS-----------SRPHSALGSSGSYRSGRSSLGPGSAIFSTGVKLNSN------TTTPEPPG-LESRPNSQQQGRLVSGRRMCSRCEQPLGKGAAMVIDSLELCFHIGCFKCVSCRTELGRGPESGAQVRVRHRQLFCNTCYCRIRVCSSISK", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . *. :: **:*.* . .** :**:*:*******.:***:::::**:*********:*:**:** ::**:************:*.****:::*:.**:******:*******: :*:* ** *:***** *** :* ****: : : * : .* : * .:* :: . ::****.:**:*: **: : :** **: . ** ** : : * * : .: :: .:*** ****: : ::..* *:*. : :* : .. :. . .: :*** *:. : . * :* .. . *.:* :. . : **. :* :. : : .:: : .* **: *:: . . .:.. .*.: :*: *: .::.: : . :*::. . .. : . . .. : :::: : ** . . .:: *::*:::.::**.: **::**::**.:*:* .**: ** ****:** : :* : .** . . . . . . . . : . . :... : : : :. :: * . :**:**: ::::: **:: * .****:.. :.:**: :::**. * . . . . : . :* . *:. * . * . . .* . :. : .:**:.:**.*.. *** .** * * ** *****: : .***:::.. :. . .:::. * * : * *:**:** *: . : .: . :. :. . . : * * . ..: .:: .: ..: *.*:: :: **::::. : * ** ****:***:** **:***:***:::**** ***::*:** *: :*: .. .. . . : * :: : : :. : ..: . * . : * . .: :*.:: * *: . . . :. : :* ** ***:****:*.*:.*.***** .:*: **.: : :** **:***. . ** .: . : ** . * .: * .. . : . .. :..... .: :.* ***:::** *: *******:*::* *.:*: **** * :** *..:**:**:*::**:** ** *:: . : ", "identical_positions": 338, "similar_positions": 422, "identity": "16.57%" }, { "cls_id": "homologset.agr.MGI:1353589", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9HC52-1", "uniprot_id": "CBX8_HUMAN", "id": "Q9HC52-1", "name": "Chromobox protein homolog 8", "aln": "MELSAVGER---------------VFAAEALLKRRIRKGRMEYLVKWKGWSQKYSTWEPEENILDARLLAAFEEREREMELYGPKKRGPKPKTFLLKAQAKAKAKTYEFRSDSARGIRIPYPGRSPQDLASTSRAREGLRNMGLSPPASSTSTSSTCRAEAPRDRDRDRDRDRERDRERERERERERERERERERGTSRVDDKPSSPGDSSK-KRGPKPRKELPDPSQRPLGEPSAGLGEYLK-----GRKLDDTPSGAGKFPAGHSVIQLARRQ--DSDLVQCGVTSPSSAEATGKLAVDTFPARVIKHRAAFLEAKGQGALDPNGTRVRHGSGPPSSGGGLYRDMGAQGGRPSLIARIPVARILGDPEEESWSPSLTNLEK-VVVTDVTSNFLTVTIKESNTDQGFFKEKR---------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9QXV1-1", "uniprot_id": "CBX8_MOUSE", "id": "Q9QXV1-1", "name": "Chromobox protein homolog 8", "aln": "MELSAVGER---------------VFAAEALLKRRIRKGRMEYLVKWKGWSQKYSTWEPEENILDARLLAAFEEREREMELYGPKKRGPKPKTFLLKAQAKAKAKTYEFRSDSTRGIRIPYPGRSPQDLASTSRAREGLRNTGLPPPGSSTST---CRADPPRDRDRERDR------------------------GTSRVDDKPSSPGDSSK-KRGPKPRKEPLDPSQRPLGEPSAGLGEYLK-----GRKLDETSSGTGKFPAGHSVIQLARRQ--DSDLVQYGVTSPSSAEASSKLAVDTFPARVIKHRAAFLEAKGQGALDPGGARVRHSSGTPASVGSLYRDMGAQGGRPSLIARIPVARILGDPEEESWSPSLTNLEK-VVVTDVTSNFLTVTIKESNTDQGFFKEKR---------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P26017-1", "uniprot_id": "PC_DROME", "id": "P26017-1", "name": "Polycomb group protein Pc", "aln": "MTGRGKGSKGKLGRDNATDDPVDLVYAAEKIIQKRVKKGVVEYRVKWKGWNQRYNTWEPEVNILDRRLIDIYEQTNK--SSGTPSKRGIKKKEKEPDPEPESEEDEYTFTENDVDTHQATTSSATHDKESKKEKKHHHHHHHHHHIKSERNSG---RRSESPLTHHHHHHHHES---------------------KRQRIDHSSSSNSSFTHNSFVPEPDSNSSSSEDQPLIG-TKRKAEVLKESGKIGVTIKTSPDGPTIKPQPTQQVTPSQQQPFQDQQQAEKIASEAATQLKSEQQATPLATEAINTTPAESGAEEEEVANEEGN--QQAPQVPSENNNIPKPCNNLAINQKQPLTPLSPRALP---PRFWLPAKCNISNRVVITDVTVNLETVTIRECKTERGFFRERDMKGDSSPVA", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* . *.: *:*** ::::*::** :** ******.*:*.***** **** **: :*: :: . *.*** * * ..:.::: . * * .:.. : . .. : :. :...: :. :: .. .* *::.* :.:.:.: .*:*...** .. :: . *:* .: ...::** : .* ** * .:. :..*. * . : :::* :.: ::* :::: ..: . .:.:..*: .* *: : . : * ::.. *:. ..: : . . . . .* * . * *: *:.: **:**** *: ****:*.:*::***:*: ", "identical_positions": 85, "similar_positions": 148, "identity": "20.14%" }, { "cls_id": "homologset.agr.MGI:1353592", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9QY80-1", "uniprot_id": "HACD1_MOUSE", "id": "Q9QY80-1", "name": "Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase 1", "aln": "MG------KGDWRQGRVEMPCAHVSRLHKTCVQVRVRVTMASSEEDGTNG-ASEASDEKEAAGKRRRLGLLATAWLTFYNIAMTAGWLVLAIAMVRFYMEKG----THRGLYKSIQKTLKFFQTFALLEVVHCLIGIVPTSVLVTGVQVSSRIFMVWLITHSIKPIQNEES--VVLFLVSWTVTEITRYSFYTFSLLDH--LPHFIKWARYNLFIILYPVGVAGELLTIYAALPYVKKSGMFSVRLPNKYNVSFDYYYFLLITMASYIPLFPQLYFHMLRQRRKVLHGEVIAEKDD---", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "B0YJ81-1", "uniprot_id": "HACD1_HUMAN", "id": "B0YJ81-1", "name": "Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase 1", "aln": "MGRLTEAAAAGSGSRAAGWAGSPPTLLPLSPTSPRCAATMASSDEDGTNGGASEAGEDREAPGERRRLGVLATAWLTFYDIAMTAGWLVLAIAMVRFYMEKG----THRGLYKSIQKTLKFFQTFALLEIVHCLIGIVPTSVIVTGVQVSSRIFMVWLITHSIKPIQNEES--VVLFLVAWTVTEITRYSFYTFSLLDH--LPYFIKWARYNFFIILYPVGVAGELLTIYAALPHVKKTGMFSIRLPNKYNVSFDYYYFLLITMASYIPLFPQLYFHMLRQRRKVLHGEVIVEKDD---", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A0G2L0Q2-1", "uniprot_id": "A0A0G2L0Q2_DANRE", "id": "A0A0G2L0Q2-1", "name": "Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase", "aln": "---------------------------------------MASGEEDGTVE-------EKETNNKKRTKGAIVTAWLTFYNIAMTAGWLVLTVAMVKYYLQKG----THKGLYRNIARTLKFFQTFALLEVGHCAIGIVRTSVIVTGVQVCSRIFMVWFITNSIRQIQNEES--VILFVVVWTVTEITRYSFYTFNLLNH--LPYFIKWARYNMFIVMYPLGVVGELLTIHAALPYVRRSGMYSLRLPNKYNVSFDYYYFLIIVMLSYIPLFPQLYFHMLRQRRRVLHGEIIVEKDE---", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P40857-1", "uniprot_id": "HACD_YEAST", "id": "P40857-1", "name": "Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase PHS1", "aln": "---------------------------------------MSKKLASPLS-------------------------FLPLYNLLSAVGWSYLLYLVISLYPKVG-----QPAFFYQTKNVATLVQCGAIIEIINSFLGVVRSPLLTTVAQVSSRLLVVLGIFQLLPNTSGVQSVVYISLLLAWSITEIVRYLYYFFMLVFKNGAPKILILLRYNLFWILYPTGVASELRIIYCALNAAES------------QYSLLYKRILIAAMLAYIPGFPMLFLHMVAQRKKVMKSLRSSFGKKLI-", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "Q9VKD2-1", "uniprot_id": "Q9VKD2_DROME", "id": "Q9VKD2-1", "name": "Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase", "aln": "---------------------------------------MSAKAVSKSSK-----------PGASKEPSAVTKLYLFAYNAGQVVGWSYILWQLVNYYILQGPEFRAQVTLWEYTRLAVIIFQNAAFVEILNASFGLVKSNPVVTGFQVFSRMMVVVGVVMATP--TGKVSPGLPIALLAWAITEIIRYGYYALNIVKV--VPHFVVFLRYTTFIVLYPIGVTGELLCFWWAQSYARENSVWSVVMPNKWNATFSYFGFLWIVMLGYIPIFPQLYLHMFAQRRKILGGGSSGSPQKKAN", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *: . :* *: ..** : :: * * : :: . :.* *::*: :. :*:* : :.* ** **:::* : . * :: *::*** ** :* : :: * :: **. * ::** **..** : * .. : :: * :* .* .*** ** *::**. **:::: . .. ", "identical_positions": 50, "similar_positions": 64, "identity": "16.72%" }, { "cls_id": "homologset.agr.MGI:1353596", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q6AYR4-1", "uniprot_id": "TOR2A_RAT", "id": "Q6AYR4-1", "name": "Torsin-2A", "aln": "MAVARHGCPPWGSILGLLVLALAAAAAWDVSFLRCSLG----------SFCECDFWPDLPG----LECDLARHLAGQHLAKALVVKSLKAFVQDPAPS-KPLVLSLHGWTGTGKSYVSSLLAQYLFRGGLRSPHVHHFSPIIHFPHPSHTEQYKNELKSWVQGNLTACGRSLFLFDEMDKLPPGLMEVLKPFLGPSWVVYGTNYRKAIFIFISNTGGEQINQVALEAWRSRRDREEISLQEVEPAVSQAVLDNPHHGFWRSGIMEEQLLDAVVPFLPLQRHHVRHCVLNELAQLGLEPR----EEVVQAVLDSTTYFPEEEQLFSSNGCKTVASRITFFL-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8R1J9-1", "uniprot_id": "TOR2A_MOUSE", "id": "Q8R1J9-1", "name": "Torsin-2A", "aln": "MAVARHGYRPWGSILGLLGLALAAAAAWDVASLRCTFG----------SFCECDFWPDLPG----LECDLAQHLAGQHLAKALVVKSLKAFVQDPAPS-KPLVLSLHGWTGTGKSYVSSLLAQHLFRDGLRSPHVHHFSPIIHFPHPSRTEQYKKELKSWVQGNLTACGRSLFLFDEMDKLPPGLMEVLQPFLGPSWVVYGTNYRKAIFIFISNAGGEQINQVALEAWRSHRDREEISLQEVEPVISRAVMDNPQHGFWRSGIMEEHLLDAVVPFLPLQRHHVRHCVLNELAQLGLEPS----EEVVQAVLDSTTYFPEVEQLFSSNGCKTVASRLTFFL-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q5JU69-1", "uniprot_id": "TOR2A_HUMAN", "id": "Q5JU69-1", "name": "Torsin-2A", "aln": "MAAATRGCRPWGSLLGLLGLVSAAAAAWDLASLRCTLG----------AFCECDFRPDLPG----LECDLAQHLAGQHLAKALVVKALKAFVRDPAPT-KPLVLSLHGWTGTGKSYVSSLLAHYLFQGGLRSPRVHHFSPVLHFPHPSHIERYKKDLKSWVQGNLTACGRSLFLFDEMDKMPPGLMEVLRPFLGSSWVVYGTNYRKAIFIFISNTGGKQINQVALEAWRSRRDREEILLQELEPVISRAVLDNPHHGFSNSGIMEERLLDAVVPFLPLQRHHVRHCVLNELAQLGLEPR----DEVVQAVLDSTTFFPEDEQLFSSNGCKTVASRIAFFL-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "O77277-1", "uniprot_id": "TORS_DROME", "id": "O77277-1", "name": "Torsin-like protein", "aln": "MMSFPRMLSLCLSVLVILPLPLQSVDPLTIGAVGAVALGAYFKEHTYCRFAECCDDRNIPARIDELERSLERTLIGQHIVRQHIVPALKAHIASGNKSRKPLVISFHGQPGTGKNFVAEQIADAMYLKGSRSNYVTKYLGQADFPKESEVSNYRVKINNAVRDTLRSCPRSLFIFDEVDKMPSGVFDQLTSLVDYNAFVDGTDNTKAIFIFLSNTAGSHIASHLGSVMKNGRLREDTRLSDFEPLLRKAAYN-MDGGMKKTTMIESHVIDHFIPFLPMEKAHVIKCLEAELLRWRRDPKQANNQKIIEDIINSSISYDRTHSLFAISGCKTLEKKVAMAIY", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* : *:* :* * :. . :. : . *.** ::*. ** .* : * ***:.: :* :***.: . : ****:*:** .****.:*:. :*. :: * ** * :: .**: *. ..*: .::. *:..* :* ****:***:**:*.*::: * .::. . .* **: ******:**:.*.:* . .. :. * **: *.:.** : :*. : . *: .: ::*.:::* .:****::: ** :*: ** : :* ::::: :::*: : . ..**: .****: .:::: : ", "identical_positions": 96, "similar_positions": 125, "identity": "28.15%" }, { "cls_id": "homologset.agr.MGI:1353598", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "E9PSK7-1", "uniprot_id": "JIP3_RAT", "id": "E9PSK7-1", "name": "C-Jun-amino-terminal kinase-interacting protein 3", "aln": "-------MMEIQMDEGGGVVVYQDDYCSGSVMSER-------VSGLAGSIYREFERLIHCYDEEVVKELMPLVVNVLENLDSVLSENQEHEVELELLREDNEQLLTQYEREKALRKQAEEKFIEFEDALEQEKKELQIQVEHYEFQTRQLELKAKNYADQISRLEERESEMKKEYNALHQRHTEMIQTYVEHIERSKMQQVGGGGQTESSLPGRS--------RKERPTSLNVFPLADGMVRAQMGGKLVPAGDHWHLSDLGQLQSSSSYQCPNDEMSESGQSSAAATPSTTGTKSNTPTSSVPSAAVTPLNESLQPLGDYGSVTKNNKRARE-KRNSRNMEVQVTQEMRNVSIGMGSSDEWSDVQDIIDSTPELDVCPETRLDRTGSSPTQGIVNKAFGINTDSLYHELSTAGSEVIGDVDEGADLLGEFS------GMGKEVGNLLLENSQLLETKNALNVVKNDLIAKVDQLSGEQEVLKGELEAAKQAKVKLENRIKELEEELKRVKSEAVTARREPREEVED---------DKIPMAQRRRFTRVEMARVLMERNQYKERLMELQEAVRWTEMIRASREHPSVQEKKKSTIWQFFSRLFSSSSSP-----------PPAKRSYPSVNIHYKSPTTAGFSQRRN--------HALCQISAGSRPLEFFPDD-----------DCTSSARREQKREQYRQVREHVRNDDGRLQACGWSLPAKYKQLSPNGG--------------QEDTRMKNVPVPVYCRPLVEKDPSTKLWCAAGVNLSG-WKPNEEDSSNGPKPAPGRDPLTCDREGEGEPKSTHPSPEKKKA----KEVPEADATSSRVWILTSTLTTSKVVIIDANQPGTVVDQFTVCNAHVLCISSIPAASDSDYPPGDMFLDSDVNP----EDSGADGVLAGITLVGCATRCNVPRSNCSSRGDTPVLDKGQGDVAATANGKVNPSQSTEEATEATEVPDP-GPSESEATTVRPGPLTEHVFTDPAPTQSSSTQPASENGSESDGSIVQPQVEPSGESSATTSSAAPTMWLGAQNGWLYVHSAVANWKKCLHSIKLKDSVLSLVHVKGRVLVALADGTLAIFHRGEDGQWDLSNYHLMDLGHPHHSIRCMAVVDDRVWCGYKNKVHVIQPKTMQIEKSFDAHPRRESQVRQLAWIGDGVWVSIRLDSTLRLYHAHTHQHLQDVDIEPYVSKMLGTGKLGFSFVRITALLIAGNRLWVGTGNGVVISIPLTETVVLHRGQLLGLRANKTSPTSGEGTRPGGIIHVYGDDSSDKTASSFIPYCSMAQAQLCFHGHRDAVKFFVSVPGNVLATLNGSVLDSPSEGPGPAAPAADAEGQKLKNALVLSGGEGYIDFRIGDGEDDETEEGTGDVN-QTKPSLSKAERSHIIVWQVSYTPE", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9ESN9-1", "uniprot_id": "JIP3_MOUSE", "id": "Q9ESN9-1", "name": "C-Jun-amino-terminal kinase-interacting protein 3", "aln": "-------MMEIQMDEGGGVVVYQDDYCSGSVMSER-------VSGLAGSIYREFERLIHCYDEEVVKELMPLVVNVLENLDSVLSENQEHEVELELLREDNEQLLTQYEREKALRKQAEEKFIEFEDALEQEKKELQIQVEHYEFQTRQLELKAKNYADQISRLEERESEMKKEYNALHQRHTEMIQTYVEHIERSKMQQVGGSGQTESSLPGRS--------RKERPTSLNVFPLADGMVRAQMGGKLVPAGDHWHLSDLGQLQSSSSYQCPNDEMSESGQSSAAATPSTTGTKSNTPTSSVPSAAVTPLNESLQPLGDYVSVTKNNKQARE-KRNSRNMEVQVTQEMRNVSIGMGSSDEWSDVQDIIDSTPELDVCPETRLERTGSSPTQGIVNKAFGINTDSLYHELSTAGSEVIGDVDEGADLLGEFSVRDDFFGMGKEVGNLLLENSQLLETKNALNVVKNDLIAKVDQLSGEQEVLKGELEAAKQAKVKLENRIKELEEELKRVKSEAVTARREPREEVEDVSSYLCTELDKIPMAQRRRFTRVEMARVLMERNQYKERLMELQEAVRWTEMIRASREHPSVQEKKKSTIWQFFSRLFSSSSSP-----------PPAKRSYPSVNIHYKSPTAAGFSQRRS--------HALCQISAGSRPLEFFPDD-----------DCTSSARREQKREQYRQVREHVRNDDGRLQACGWSLPAKYKQLSPNGG--------------QEDTRMKNVPVPVYCRPLVEKDPSTKLWCAAGVNLSG-WKPHEEDSSNGPKPVPGRDPLTCDREGEGEPKSTHPSPEKKKA----KETPEADATSSRVWILTSTLTTSKVVIIDANQPGTIVDQFTVCNAHVLCISSIPAASDSDYPPGEMFLDSDVNP----EDSGADGVLAGITLVGCATRCNVPRSNCSSRGDTPVLDKGQGDVATTANGKVNPSQSTEEATEATEVPDP-GPSESEATTVRPGPLTEHVFTDPAPTPSSSTQPASENGSESNGTIVQPQVEPSGELSTTTSSAAPTMWLGAQNGWLYVHSAVANWKKCLHSIKLKDSVLSLVHVKGRVLVALADGTLAIFHRGEDGQWDLSNYHLMDLGHPHHSIRCMAVVNDRVWCGYKNKVHVIQPKTMQIEKSFDAHPRRESQVRQLAWIGDGVWVSIRLDSTLRLYHAHTHQHLQDVDIEPYVSKMLGTGKLGFSFVRITALLIAGNRLWVGTGNGVVISIPLTETVVLHRGQLLGLRANKTSPTSGEGTRPGGIIHVYGDDSSDKAASSFIPYCSMAQAQLCFHGHRDAVKFFVSVPGNVLATLNGSVLDSPSEGPGPAAPAADAEGQKLKNALVLSGGEGYIDFRIGDGEDDETEECAGDVN-QTKPSLSKAERSHIIVWQVSYTPE", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9UPT6-1", "uniprot_id": "JIP3_HUMAN", "id": "Q9UPT6-1", "name": "C-Jun-amino-terminal kinase-interacting protein 3", "aln": "-------MMEIQMDEGGGVVVYQDDYCSGSVMSER-------VSGLAGSIYREFERLIHCYDEEVVKELMPLVVNVLENLDSVLSENQEHEVELELLREDNEQLLTQYEREKALRRQAEEKFIEFEDALEQEKKELQIQVEHYEFQTRQLELKAKNYADQISRLEERESEMKKEYNALHQRHTEMIQTYVEHIERSKMQQVGGNSQTESSLPGR---------RKERPTSLNVFPLADGTVRAQIGGKLVPAGDHWHLSDLGQLQSSSSYQCPQDEMSESGQSSAAATPSTTGTKSNTPTSSVPSAAVTPLNESLQPLGDYGVGSKNSKRARE-KRDSRNMEVQVTQEMRNVSIGMGSSDEWSDVQDIIDSTPELDMCPETRLDRTGSSPTQGIVNKAFGINTDSLYHELSTAGSEVIGDVDEGADLLGEFSVRDDFFGMGKEVGNLLLENSQLLETKNALNVVKNDLIAKVDQLSGEQEVLRGELEAAKQAKVKLENRIKELEEELKRVKSEAIIARREPKEEAEDVSSYLCTESDKIPMAQRRRFTRVEMARVLMERNQYKERLMELQEAVRWTEMIRASREHPSVQEKKKSTIWQFFSRLFSSSSSP-----------PPAKRPYPSVNIHYKSPTTAGFSQRRN--------HAMCPISAGSRPLEFFPDD-----------DCTSSARREQKREQYRQVREHVRNDDGRLQACGWSLPAKYKQLSPNGG--------------QEDTRMKNVPVPVYCRPLVEKDPTMKLWCAAGVNLSG-WRPNEDDAGNGVKPAPGRDPLTCDREGDGEPKSAHTSPEKKKA----KELPEMDATSSRVWILTSTLTTSKVVIIDANQPGTVVDQFTVCNAHVLCISSIPAASDSDYPPGEMFLDSDVNP----EDPGADGVLAGITLVGCATRCNVPRSNCSSRGDTPVLDKGQGEVATIANGKVNPSQSTEEATEATEVPDP-GPSEPETATLRPGPLTEHVFTDPAPTPSSGPQPGSENGPEPDSSSTRPEPEPSGDPTGAGSSAAPTMWLGAQNGWLYVHSAVANWKKCLHSIKLKDSVLSLVHVKGRVLVALADGTLAIFHRGEDGQWDLSNYHLMDLGHPHHSIRCMAVVYDRVWCGYKNKVHVIQPKTMQIEKSFDAHPRRESQVRQLAWIGDGVWVSIRLDSTLRLYHAHTHQHLQDVDIEPYVSKMLGTGKLGFSFVRITALLVAGSRLWVGTGNGVVISIPLTETVVLHRGQLLGLRANKTSPTSGEGARPGGIIHVYGDDSSDRAASSFIPYCSMAQAQLCFHGHRDAVKFFVSVPGNVLATLNGSVLDSPAEGPGPAAPASEVEGQKLRNVLVLSGGEGYIDFRIGDGEDDETEEGAGDMS-QVKPVLSKAERSHIIVWQVSYTPE", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AC58IA37-1", "uniprot_id": "A0AC58IA37_DANRE", "id": "A0AC58IA37-1", "name": "C-Jun-amino-terminal kinase-interacting protein 3", "aln": "-------MMELDE------VVYQDDYGAVSVMSER-------VTGLASSIYQEFERLIKTYDEEVVKELMPLVVNVLENLDSVLTENQEHEVELELLKEDNEQLITQYEREKALRKQAEEKFIEFEDALEADKKDLQTTVETLELQAKQLELKSKNYADQISRLEERESDMKKEYNALHQRHTEMIQTYVEHIERSKLQQSGSN-QSESTGCGRSQRHNWRKSKAERPPSLSLYPGGDGMVRGGPGGARMVSSDIWHSSDLSRPVYAPGYQE-----DGSDSDSVAATPSSTGSKSNTPTSSVPSATVTPLNDGLVSVGEYDPSRGRARDRRTGKRLSRNMEVQVSQETRNVSIGMGSSDEWSEFQEIIDSTPELDMCLDPRIFGGGNSPSQGIVNEAFGINTDSLYHEIKDAKSDIIGDVDAGAELLGEFSVRDDFFGMGKEVENLLTENKQLLETKNALNIVKNDLIAKVDELSSEQEVLREELESVKQSKTKVDQRVKELEEELKRLRAEALGASQDSKDEGGE--DYSSPLQDDVTMTQRRRFTRVEMARVLMERNQYKERLMELQEAVRWTEMIRASRESPPLPEKKKSIIWQFFARLFSSSASP-----------PPVKRPYTSVNIHYKSPSPAGYNQRRS--------QTMCQISTSTCIREFLPEEMPVNGVASLLSDSALCTRREQRREQYRQVREHMRRKDGPMQTCGWSVPSRLKQNGCQADSAPDATAKRNQATEKEDNRMKNVPVPVYCRPLVEKDPNRKLWCAAGVDLTG-WKTSSQEAAS-VKPSNGSDPLTAENEG-GDGKSEQSSPEKKKP----KELHETDPVSSRVWILTSTHSASKVVIIDANLPCSLVDQFNVCNAHVLCISSVPAASESDYPAGEIFLEQQAGDGASEEKGGVEGMLAGITIVGCATNCSVVRSNCSSRTDTPVQDRSNAPTAPVCR-SLAVSQSAEEATEAIEVTEEAGPSENADSTL--GSFTEHVFTD---------NTHSEPGVAKEKVSSAPADSEEAADERAGTSAAPTMWLGAQNGWLYVHSAVSNWKKCLHSIKLKDSVLSLVHVKGRVLVALADGTLAIFHRSEDGQWDLSNYHLMDLGRPHHSIRCMAVVHDKVWCGNKNKIHVIQPKSMQIEKSFDAHPRKESQVRQLAWIGDGVWVSIRLDSTLRLYHAHTHQHLQDVDIEPYVSKMLGTGKLGFSFVRITALLIGGNRLWVGTGNGVIISIPLTETVVLHRGQLLGLRANKVSPTS-----SGGVIHVYADDSTS-EKSSFIPYCSMAQAQLCFHGHRDAVKFFVSVPGNVLATLNGSVLDSPSESQGSSAP-AETEAQSLQNVLVLSGGEGYIDFRIGDGEDDETEEADDDEAPQMKPALSKAERSHIIVWQVSYVPE", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9GQF1-1", "uniprot_id": "JIP3_DROME", "id": "Q9GQF1-1", "name": "JNK-interacting protein 3", "aln": "MMDNDDALLNNGGPQSGAETVYGTEDNN-MVMSEKNEQVVSIVQQLAGSIYQEFERMINRYDEDVVKNLMPLLVNVLECLDASYRINQEQDVEVELLREDNEQLVTQYEREKSARKQSEQKLLEAEDLAEQENKELATRLESVESIVRMLELKHKNSLEHASRLEEREADLKKEYNKLHERYTELFKNHVDYMERTKMLMGSTHSQMSTASERMD----------VSRARLNPVARSSGPVSYG---------------------------------FASLENSVMLDTETICSVGSQSDDSGPPSLQNELDN-LSGTLERGAATDALQQQHH---ATSPQSPDSSPVVPNVPTNVG------------RSTTKKEQRSDNNLYQELS----------FQDNEESEENEIVTGSWVHPGEYASSAN--------DNYFGMGKEVENLIMENNELLATKNALNIVKDDLIVKVDELTGEVEIVREELNAMQQSRTKLRQRISELEDELKKAKEQVKQQNTEQEE-------------NDVPLAQRKRFTRVEMAMVLMERNQYKERLMELQEAVRLTEILRASRTVDNLDRKSKQSIWKYFSNLFTPSNRPTERVADGLGGGPMFRHTGGGSPAHSHGSPSRGSGGGDNRLALTSGQPPVHPASAGLANALIMPKDYAE--------EGSSERISARRREQYRQLRAHVQKEDGRLHAYGWSLPINKASQEANPN-----------------RHSGGVPVPVYCNPLAEASPHMKVFCAAGVNLHGGFTKNGQSLIPANSPYAPKSTLKIAEITSPTADQSMEALDRQMARVSLETLEPETQLSSFVWICTSTHAASTVSVVDANQSATVLDAFPICASHLLCIASVQGAMESDYALLEQSEVVKAGEMLQ-RPGEGTELLGKVEFVRVKPKS----DDEQNSNEKQQQEEEEAKEATEKSNEQLPAVSAEEPLGNVEAIKIRQPLPGAPQRLSTDGNQTNNNNN----------SSSSSNLLFATKSLNPILETKDRDEPAMSSVGPTMWLGAQDGWLYVHSSVGRWHECLHRVLLPDAVLAIVHVEARVVVALANAQLAVFRRQTDGQWDLNSYHLVTLGDRNHSIRCLCVAGERIWAAHRNKIFIVDPVSLNIVHSLDAHPRKESQVRQMAATGAGVWVSIRLDSTLRLYNTHTFEHKQDVDIEPYVSKMLGTGKLGFSFVRITALMVSCNRLWIGTSNGVIISVPLAEVQ----------------------------------PKSSSDPHGQMPLCCMANAQLSFHGHRDAVKFFVSVPMLQQPNLNGGLTFT----------------NKRPDMLVMCGGEGYIDFRINDNDMENSIQLEPNQT-----IENRGDKSYLIVWHVSQR--", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ::: .** : ****: * **.***:****:*: ***:***:****:***** **: ***::**:***:******:*******: *:*:*:*::* ** * ::*:* :* * .: **** ** :: *******:::***** **:*:**:::.:*:::**:*: . * .:: . *. . ..* * * ..*. ..: : .. . .* *.: . *:: * : : : : . : : **. .:* **.: : : .: . * * :* :*: . *: .*: ****** **: **.:** ******:**:***.***:*:.* *::: **:: :*::.*: :*:.***:***: : :. : .: :.:.::**:******** ******************** **::**** : .*.*. **::*:.**:.* * * ::. . * :.... * . . .: *:. ::*.: : : ::******:* *::..** ::: ***:* . . : . : .*******.**.* .* *::*****:* * : :. .* ..*. . .. : ::: . : ** *** *** ::*.* ::*** . :::* * :* :*:***:*: .* :***. : ... . :*. : :* ... .: .. :. :. :. *. . : *:**. *. . * : . : .: . *. . * . . : :*..********:*******:*..*::*** : * *:**::***:.**:****:. **:*:* ******..***: ** :*****:.*. :::*.. :**:.:::* :::* :*:*****:******:* * ***************::**.:* ****************************::. .***:**.***:**:**:*. .:. . :* *.**:***.*************** ..***.: : :. : **:.**********.*.: ::: : : .:.::*::***:** ", "identical_positions": 452, "similar_positions": 356, "identity": "31.94%" }, { "cls_id": "homologset.agr.MGI:1353604", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "F1M342-1", "uniprot_id": "F1M342_RAT", "id": "F1M342-1", "name": "", "aln": "-------------------------------------------------------------------------------------------------------------------MNTTDSGVN---------------CLCAICGDRATGKHYGASSCDGCKGFFRRSIRKSHVYSCRFSRQCVVDKDKRNQCRYCRLRKCFRAGMKKEAVQNERDRISTRRSTYEGTNIP---SINTLAQAEVRSCQ---ISVPNPSASTDINVKKIASISDVCESMKQQLLVLVEWAKYIPAFCELPLDDQVALLRAHAGEHLLLGATKRSMMYKDILLLGNHYVIHRNSCE------VEVSRVANRVLDELVRPFQEIQIDDNEYACLKAIVFFDPDAKGLSDPGKIKNMRFQVQISLEDYINDRQYDSRGRFGELLLLLPTLQSITWQMIEQIQFVKLFGMVKIDNLLQEMLLGGAANDGGH-PHHPMHPHLSQDPLTG---------------------------------------------------------QTILLGPMSTLVHTDQIATPETPLPSPPQGSGQEQYKIT-----------------ANQASVISHQPLSKQKQL-------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9WUU6-1", "uniprot_id": "HNF4G_MOUSE", "id": "Q9WUU6-1", "name": "Hepatocyte nuclear factor 4-gamma", "aln": "-------------------------------------------------------------------------------------------------------------------MNTTDSGVN---------------CLCAICGDRATGKHYGASSCDGCKGFFRRSIRKSHVYSCRFSRQCVVDKDKRNQCRYCRLRKCFRAGMKKEAVQNERDRISTRRSTYEGSNIP---SINTLAQAEVRSCQ---ISVPSPSSSTDINIKKIASISDVCESMKQQLLVLVEWAKYIPAFCELPLDDQVALLRAHAGEHLLLGATKRSMMYKDILLLGNHYVIHRNSCE------VEVSRVANRVLDELVRPFQEIQIDDNEYACLKAIVFFDPDAKGLSDPVKIKNMRFQVQISLEDYINDRQYDSRGRFGELLLLLPTLQSITWQMIEQIQFVKLFGMVKIDNLLQEMLLGGAANDGSH-LHHPMHPHLSQDPLTG---------------------------------------------------------QTILLGPMSTLVHTDQIATPETPLPSPPQGSGQEPYKIT-----------------ANQASVISHQSLSKQKQL-------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q14541-1", "uniprot_id": "HNF4G_HUMAN", "id": "Q14541-1", "name": "Hepatocyte nuclear factor 4-gamma", "aln": "-------------------------------------------------------------------------------------------------------------------MNTTDNGVN---------------CLCAICGDRATGKHYGASSCDGCKGFFRRSIRKSHVYSCRFSRQCVVDKDKRNQCRYCRLRKCFRAGMKKEAVQNERDRISTRRSTFDGSNIP---SINTLAQAEVRSRQ---ISVSSPGSSTDINVKKIASIGDVCESMKQQLLVLVEWAKYIPAFCELPLDDQVALLRAHAGEHLLLGATKRSMMYKDILLLGNNYVIHRNSCE------VEISRVANRVLDELVRPFQEIQIDDNEYACLKAIVFFDPDAKGLSDPVKIKNMRFQVQIGLEDYINDRQYDSRGRFGELLLLLPTLQSITWQMIEQIQFVKLFGMVKIDNLLQEMLLGGASNDGSH-LHHPMHPHLSQDPLTG---------------------------------------------------------QTILLGPMSTLVHADQISTPETPLPSPPQGSGQEQYKIA-----------------ANQASVISHQHLSKQKQL-------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A0R4IJK6-1", "uniprot_id": "A0A0R4IJK6_DANRE", "id": "A0A0R4IJK6-1", "name": "", "aln": "---------------------------------------------MKFSPTPLPKSLLDMDVANYCEGLDPTYSTLGFENAEVLYCGEN--------------------MPTEPNISQGENGVS---------------SNCAICGDKATGKHYGASSCDGCKGFFRRSIRKSHVYSCRFNRQCVVDKDKRNQCRFCRLHKCFRAGMKKEAVQNERDRISSRRNIQDSHDLP---PITALAHAEALSQQQ--ITAASPMGPADVSEKKSATISDVCESMKQQLLVLVEWAKYIPAFGELPLDDQVSLLRAHAGEHLLLGVAKRSMSYKDLLLLGNGCVIHRNCPE------PEIGRVSNRVLDELVLPFQDIQIDDNEYAALKAIVFFDPDAKSLRDPSKIKAMRYQVQMSLEDYINDRQYDSRGRFGELLLLLPTLQSITWQMIEQLQFIKLFGLAKIDNLLQEMLLGGLTTEQPH-LHHNGHP---QIPITG---------------------------------------------------------QTIVISSIPGPAHP-QMASPETPIPSPTSVQNQEVFKPS-----------------GSPALLLPPQTMPNRPSPEPPL---------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P49866-1", "uniprot_id": "HNF4_DROME", "id": "P49866-1", "name": "Transcription factor HNF-4 homolog", "aln": "MMKHPQDLSVTDDQQLMKVNKVEKMEQELHDPESESHIMHADALASAYPAASQPHSPIGLALSPNGGGLGLSNSSNQSSENFALCNGNGNAGSAGGGSASSGSNNNNSMFSPNNNLSGSGSGTNSSQQQLQQQQQQQSPTVCAICGDRATGKHYGASSCDGCKGFFRRSVRKNHQYTCRFARNCVVDKDKRNQCRYCRLRKCFKAGMKKEAVQNERDRISCRRTSNDDPDPGNGLSVISLVKAENESRQSKAGAAMEPNINEDLSNKQFASINDVCESMKQQLLTLVEWAKQIPAFNELQLDDQVALLRAHAGEHLLLGLSRRSMHLKDVLLLSNNCVITRHCPDPLVSPNLDISRIGARIIDELVTVMKDVGIDDTEFACIKALVFFDPNAKGLNEPHRIKSLRHQILNNLEDYISDRQYESRGRFGEILLILPVLQSITWQMIEQIQFAKIFGVAHIDSLLQEMLLGGELADNPLPLSPPNQSNDYQSPTHTGNMEGGNQVNSSLDSLATSGGPGSHSLDLEVQHIQALIEANSADDSFRAYAASTAAAAAAAVSSSSSAPASVAPASISPPLNSPKSQHQHQQHATHQQQQESSYLDMPVKHYNGSRSGPLPTQHSPQRMHPYQRAVASPVEVSSGGGGLGLRNPADITLNEYNRSEGSSAEELLRRTPLKIRAPEMLTAPAGYGTEPCRMTLKQEPETGY", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :. .*.. ******:*********************:**.* *:*** *:************:***:***:**************** **. :. : .: :*.:** * * :. .* *:. *: *:*.***********.****** **** ** *****:************* ::*** **:***.* ** *:. : ::.*:. *::**** :::: ***.*:*.:**:*****:**.* :* :** :*.*: .*****.****:*******:**:**.***********:** *:**:.:**.********* : :. * * : :.. . . :: ..*: ** . :: . .. : :. * .:: ", "identical_positions": 214, "similar_positions": 100, "identity": "30.4%" }, { "cls_id": "homologset.agr.MGI:1353605", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O14657-1", "uniprot_id": "TOR1B_HUMAN", "id": "O14657-1", "name": "Torsin-1B", "aln": "MLRAGWLRGAAALALLLAARVVAAFEPITVGLAIGAASAITGYLSYNDIYCRFAECCRE-ERPLNASALKLDLEEKLFGQHLATEVIFKALTGFRNNKN-PKKPLTLSLHGWAGTGKNFVSQIVAENLHPKGLKSNFVHLFVSTLHFPHEQKIKLYQDQLQKWIRGNVSACANSVFIFDEMDKLHPGIIDAIKPFLDYYEQVDGVSYRKAIFIFLSNAGGDLITKTALDFWRAGRKREDIQLKDLEPVLSVGVFNNKHSGLWHSGLIDKNLIDYFIPFLPLEYRHVKMCVRAEMRARG----SAIDEDIVTRVAEEMTFFPRDEKIYSDKGCKTVQSRLDFH--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9ER41-1", "uniprot_id": "TOR1B_MOUSE", "id": "Q9ER41-1", "name": "Torsin-1B", "aln": "MRRIGAFGGSTALWALLAAHVAGAFEPVSVGIAIGAVSALTGYLSYTDFYCRFTECCHE-ERPLNTSALKLDLEEKLFGQHLATEVILKALTGFRNNKN-SKKPLTLSLHGWAGTGKNFISQIVAENLYPKGLKSNFVHLFVSTLHFPHEQKIKVYQDQLQKWIRGNVSACGSSVFIFDEMDKLHPGIIDAIKPFLDYYEQVDGISYRRAIFIFLSNAGGDLITKTALDFWRAGRKREEIQLKDLEPVLSVGVFNNKHSGLWHSGLIDKNLIDYFIPFLPLEYKHVKMCVRAEMRARG----AAVDEDVVTSVADEMTFFPKDEKIYSDKGCKTVQSRLDFH--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O77277-1", "uniprot_id": "TORS_DROME", "id": "O77277-1", "name": "Torsin-like protein", "aln": "MMSFPRMLSLCLSVLVILPLPLQSVDPLTIG-AVGAVALGAYFKEHT--YCRFAECCDDRNIPARIDELERSLERTLIGQHIVRQHIVPALKAHIASGNKSRKPLVISFHGQPGTGKNFVAEQIADAMYLKGSRSNYVTKYLGQADFPKESEVSNYRVKINNAVRDTLRSCPRSLFIFDEVDKMPSGVFDQLTSLVDYNAFVDGTDNTKAIFIFLSNTAGSHIASHLGSVMKNGRLREDTRLSDFEPLLRKAAYN-MDGGMKKTTMIESHVIDHFIPFLPMEKAHVIKCLEAELLRWRRDPKQANNQKIIEDIINSSISYDRTHSLFAISGCKTLEKKVAMAIY", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* : . :: . :.:*:::* *:**.: : : .:. ****:*** : : * . . *: .**..*:***:. : *. **... . * .:***.:*:** .******::: :*: :: ** :**:* ::. .**:*.::. *: :::: :*..: :* *:*****:**: .*::* :..::** *** . :********:.*. *:. .. : ** **: :*.*:**:* ..:* ..*: :: :*:.::**:******:* ** *:.**: * ::.:: : :. : : ..::: .****::.:: : ", "identical_positions": 105, "similar_positions": 137, "identity": "30.52%" }, { "cls_id": "homologset.agr.MGI:1353606", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O54926-1", "uniprot_id": "SIVA_MOUSE", "id": "O54926-1", "name": "Apoptosis regulatory protein Siva", "aln": "--------MPKRSCPFADAAPLQLKVHVGLKELS-HGVFAERYSREVFERTKQLLFQGARAYRDHIS-SED-CSVNHLQESLKSGVVGAPQ-PARGQMLIGPDGRLTRCQAQASEGGLPRTAPIACSSCMRSVDGKAVCSQCERALCGQCVYTCWGCGALACVLCGLADYADD--GEKTLCTSCAMFEA", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P59692-1", "uniprot_id": "SIVA_RAT", "id": "P59692-1", "name": "Apoptosis regulatory protein Siva", "aln": "--------MPKRSCPFTDAAPLQLKVHVSPRELS-HGVFAERYSREVFERTKQLLFQGAQAYRDHIW-GEG-CSINHLPEPLKPGLVGAPQ-AARGQMLIGPDGRLTRCQAQASEAGLPGAAPIACSSCVRSVDGKAVCSQCERALCGQCVYTCWGCGALACVLCGLADYADDDDGEKTLCTSCAMFEA", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O15304-1", "uniprot_id": "SIVA_HUMAN", "id": "O15304-1", "name": "Apoptosis regulatory protein Siva", "aln": "--------MPKRSCPFADVAPLQLKVRVSQRELS-RGVCAERYSQEVFEKTKRLLFLGAQAYLDHVW-DEG-CAVVHLPESPKPGPTGAPR-AARGQMLIGPDGRLIRSLGQASEADPSGVASIACSSCVRAVDGKAVCGQCERALCGQCVRTCWGCGSVACTLCGLVDCSDMY--EKVLCTSCAMFET", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A2R8QL23-1", "uniprot_id": "A0A2R8QL23_DANRE", "id": "A0A2R8QL23-1", "name": "", "aln": "--------MPKRSYPFSESFSSQYKVHVGQKEMSTCGVFGLRYRQEIYEKTKSLLFNGTKAVMGRIWKAEGEEKQSDVVESDQTSVSAAHQTLLRGQTTIGLDGRLHRARSTPG----VGVCPPACGVCQRGSALRKCCSQCERQVCSSCVQQCNSCSEICCSVCTVTDYSERY--ERVLCCGCSS---", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9I7Z9-1", "uniprot_id": "Q9I7Z9_DROME", "id": "Q9I7Z9-1", "name": "Apoptosis regulatory protein Siva", "aln": "-----------------------------------------------------MLFDGETGNGQGQG-----------QNTLNPLGPGQEEPALCEQYYLLGDGSIILRN-HSIDLSNP---PLKSRCCQLPTLIHDICVNCVMDLCEECGYSCGECAKFICRNCVTLFGNRIEEEEDPLCEHCQMFLS", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q8IRY8-1", "uniprot_id": "Q8IRY8_DROME", "id": "Q8IRY8-1", "name": "", "aln": "-----------------------------------------------------MLFDGATGNGHGQG-----------QNTLNPLGPGQEEPALCEQYYLLGDGSIILRN-HSIDLSNP---PLKSRCCQLPTLIHDICVNCVMDLCEECGYSCGECAKFICRNCVTLFGNRIEEEEAPLCEHCQMFLS", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "A8JUS8-1", "uniprot_id": "A8JUS8_DROME", "id": "A8JUS8-1", "name": "Apoptosis regulatory protein Siva", "aln": "MENQVRKKAAKRSRSADGDANNNLTQRKVFVNQKMCDSRDPRKMKEVHEKTIKMLFDGAAGNRQGQG-----------QNALKPLVQGQEEPALCEQYYLLGDGSIVLRN-LRTDLSNPRLERVKSRCCQRQTLIHDICVNCVMDLCEECGYSCGECSRFICRSCVTLFGNRVEEEKDPLCEHCQMFFS", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :** * . :. :. . . * : ** : . * : * :* :* .* * *. . * * : ** * ", "identical_positions": 18, "similar_positions": 18, "identity": "9.52%" }, { "cls_id": "homologset.agr.MGI:1353609", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q99592-1", "uniprot_id": "ZBT18_HUMAN", "id": "Q99592-1", "name": "Zinc finger and BTB domain-containing protein 18", "aln": "MEFPDHSRHLLQCLSEQRHQGFLCDCTVLVGDAQFRAHRAVLASCSMYFHLFYKDQLDKRDIVHLNSDIVTAPAFALLLEFMYEGKLQFKDLPIEDVLAAASYLHMYDIVKVCKKKLKEKATTEADSTKKEEDASSCSDKVESLSDGSSHIAGDLPSDEDEGEDEKLNILPSKRDLAAEPGNMWMRLPSDSAGIPQAG-GEAEPHATAAGKT-VASPCSSTESLSQRSVTSVRDSADVDCVLDLSVKSSLSG--VENLN-SSYFSS---QDVLRSNLVQVKVEKEASCDESDVGTNDYDMEHSTVKESVSTN--------NRVQYEPAHLAPLREDSVLRELDREDKASDD--EMMTPESERVQVEGGMESSLLPYVSNIL-SPAGQIFMCPLCNKVFPSPHILQIHLSTHFREQDGIRSKPAADVNVPTCSLCGKTFSCMYTLKRHERTHSGEKPYTCTQCGKSFQYSHNLSRHAVVHTREKPHACKWCERRFTQSGDLYRHIRKFHCELVNSLSVKSEALSLPTVRDWTLEDSSQELWK", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9WUK6-1", "uniprot_id": "ZBT18_MOUSE", "id": "Q9WUK6-1", "name": "Zinc finger and BTB domain-containing protein 18", "aln": "MEFPDHSRHLLQCLSEQRHQGFLCDCTVLVGDAQFRAHRAVLASCSMYFHLFYKDQLDKRDIVHLNSDIVTAPAFALLLEFMYEGKLQFKDLPIEDVLAAASYLHMYDIVKVCKKKLKEKATTEADSTKKEEDASSCSDKVESLSDGSSHMAGDLPSDEDEGEDDKLNILPSKRDLAAEPGNMWMRLPSDSAGIPQAG-GEAEPHATAAGKT-VASPCSSTESLSQRSVTSVRDSADVDCVLDLSVKSSLSG--VENLN-SSYFSS---QDVLRSNLVQVKVEKEASCDESDVGTNDYDMEHSTVKESVSTN--------NRVQYEPAHLAPLREDSVLRELDREDKASDD--EMMTPESERVQVEGGMENSLLPYVSNIL-SPAGQIFMCPLCNKVFPSPHILQIHLSTHFREQDGIRSKPAADVNVPTCSLCGKTFSCMYTLKRHERTHSGEKPYTCTQCGKSFQYSHNLSRHAVVHTREKPHACKWCERRFTQSGDLYRHIRKFHCELVNSLSVKSEALSLPTVRDWTLEDSSQELWK", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9JKY3-1", "uniprot_id": "ZBT18_RAT", "id": "Q9JKY3-1", "name": "Zinc finger and BTB domain-containing protein 18", "aln": "MEFPDHSRHLLQCLSEQRHQGFLCDCTVLVGDAQFRAHRAVLASCSMYFHLFYKDQLDKRDIVHLNSDIVTAPAFALLLEFMYEGKLQFKDLPIEDVLAAASYLHMYDIVKVCKKKLKEKATTEADSTKKEEDASSCSDKVESLSDGSSHMAGDLPSDEDEGEDDKLNILPSKRDLAAEPGNMWMRLPSDAAGIPQAG-GEAEPHATAAGKT-VASPCSSTESLSQRSVTSVRDSADVDCVLDLSVKSSLSG--VENLN-SSYFSS---QDVLRGNLVQVKVEKEASCDESDVGTNDYDMEHSTVKESVSAN--------NRVQYEPAHLAPLREDSVLRELDREDKASDD--EMMTPESERVQVEGGMESSLLPYVSNIL-SPAGQIFMCPLCNKVFPSPHILQIHLSTHFREQDGIRSKPAADVNVPTCSLCGKTFSCMYTLKRHERTHSGEKPYTCTQCGKSFQYSHNLSRHAVVHTREKPHACKWCERRFTQSGDLYRHIRKFHCELVNSLSVKSEALSLPTVRDWTLEDSSQELWR", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q1L8W0-1", "uniprot_id": "ZBT18_DANRE", "id": "Q1L8W0-1", "name": "Zinc finger and BTB domain-containing protein 18", "aln": "MEFPDHSRHLLQCLSEQRHQGFLCDSTVLVGDAQFRAHRAVLASCSMYFHLFYKDQLDKRDIVHLNSDIVTAPAFALLLEFMYEGKLQFKSLPVEDVLAAASYLHMYDIVKVCKKKLKQKATAEADSTKREEDTSSCSDKVESFSEGGSTGR---PATADLLQSDDEDME-NKRDSPQEPGSMWMRLPSDRTTSPTTSPREAETHGPDAGKSPAGSPSSSSGSLSRRSAASRRVSADTDCVLDLSVKSSLGGGPGENIAGNPYFCSSVTPDSLQSALVQVKVEKDTGSDDDELVSGDYEMEHSGVKEPPSTNGTHLSLVAQRRLGLEAHLSALREASLASELERDDKGGDDDTDVLGGDSDRVQEAAGVESSLLPYVSSMLGAPHTQIFMCPLCNKVFPSPHILQIHLSTHFREQEGVRAKPAGDVNVPTCSICGKTFSCMYTLKRHERTHSGEKPYTCTTCGKSFQYSHNLSRHAVVHTREKPHACKWCERRFTQSGDLYRHIRKFHCELVNSLSVKSEALNLPTVRDWALEDSSQELWK", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*************************.****************************************************************.**:************************:***:******:***:*********:*:*.* *: * :.:. :: .*** . ***.******** : * :. ***.*.. ***: ..**.**: ***:**.:* * ***.************.* **: ..**.* * *:. ********::..*:.:: :.**:**** ***. *:* :* ***:.*** *: **:*:**..** ::: :*:*** .*:*.*******.:* :* *****************************:*:*:***.********:*************************** *************************************************************.*******:*********:", "identical_positions": 393, "similar_positions": 82, "identity": "72.64%" }, { "cls_id": "homologset.agr.MGI:1353611", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9EQS5-1", "uniprot_id": "SC5D_RAT", "id": "Q9EQS5-1", "name": "Lathosterol oxidase", "aln": "MDLVLSAADYYFFT-------------------------------------------------------PYVYPAT-------WPEDNIIRQTVSLLVVTNLGAYILYFFCATLSYYFVYDHSLMKHPQFLKNQVSREIMFTVKSLPWISIPTVSLFLLELRGYSKLYDDIGDFPNGWIHLIMSVISFLFFTDMLIYWIHRGLHHRLLYKHIHKPHHIWKIPTPFASHAFHPVDGFLQSLPYHIYPFVFPLHKVVYLGLYVLVNVWTISIHDGDFRVPQIFRPFINGSAHHTDHHMLFDYNYGQYFTLWDRIGGSFKHP--SSFEGK---GPHSYVKNMTEKESNSLAENGCKSKKLC-NGEFTKNE-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O88822-1", "uniprot_id": "SC5D_MOUSE", "id": "O88822-1", "name": "Lathosterol oxidase", "aln": "MDLVLSAADYYFFT-------------------------------------------------------PYVYPAT-------WPEDNIIRQTISLLIVTNLGAYILYFFCATLSYYFVYDHSLMKHPQFLKNQVSREIVFTVKSLPWISIPTVSLFLLELRGYSKLYDDIGDFPNGWIHLMVSVVSFLFFTDMLIYWIHRGLHHRLVYKRIHKPHHIWKIPTPFASHAFHPVDGFLQSLPYHIYPFVFPLHKVVYLGLYVLVNVWTISIHDGDFRVPQILRPFINGSAHHTDHHMFFDYNYGQYFTLWDRIGGSFKHP--SSFEGK---GPHSYVKNMTEKESNSFAENGCKGKKVG-NGEFTKNK-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O75845-1", "uniprot_id": "SC5D_HUMAN", "id": "O75845-1", "name": "Lathosterol oxidase", "aln": "MDLVLRVADYYFFT-------------------------------------------------------PYVYPAT-------WPEDDIFRQAISLLIVTNVGAYILYFFCATLSYYFVFDHALMKHPQFLKNQVRREIKFTVQALPWISILTVALFLLEIRGYSKLHDDLGEFPYGLFELVVSIISFLFFTDMFIYWIHRGLHHRLVYKRLHKPHHIWKIPTPFASHAFHPIDGFLQSLPYHIYPFIFPLHKVVYLSLYILVNIWTISIHDGDFRVPQILQPFINGSAHHTDHHMFFDYNYGQYFTLWDRIGGSFKNP--SSFEGK---GPLSYVKEMTEGKRSSHSGNGCKNEKLF-NGEFTKTE-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P32353-1", "uniprot_id": "ERG3_YEAST", "id": "P32353-1", "name": "Delta(7)-sterol 5(6)-desaturase ERG3", "aln": "MDLVLEVADHYVLDDLYAKVLPASLAANIPVKWQKLLGLNSGFSNSTILQETLNSKNAVKECRRFYGQVPFLFDMSTTSFASLLPRSSILREFLSLWVIVTIFGLLLYLFTASLSYVFVFDKSIFNHPRYLKNQMAMEIKLAVSAIPWMSMLTVPWFVMELNGHSKLYMKIDYENHGVRKLIIEYFTFIFFTDCGVYLAHRWLHWPRVYRALHKPHHKWLVCTPFASHSFHPVDGFLQSISYHIYPLILPLHKVSYLILFTFVNFWTVMIHDGQYLS---NNPAVNGTACHTVHHLYFNYNYGQFTTLWDRLGGSYRRPDDSLFDPKLRDAKETWDAQVKEVEHFIKEVEGDDNDRIYENDPNTKKNN", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "***** .**:*.: *::: : *...*:*: :** ::..: . :**:* *:*** **:*:::::**::****: ** ::*.::**:*: **. *::*:.*:***: .:. * .*::. .:*:**** :* ** ** :*: :***** * : ******:***:******:.*****:::***** ** *: :**.**: ****:: .* :**:* ** **: *:*****: *****:***::.* * *: * . :: ::.* : :* ...:: *. **.: ", "identical_positions": 130, "similar_positions": 101, "identity": "35.33%" }, { "cls_id": "homologset.agr.MGI:1353616", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "B7YZU3-1", "uniprot_id": "B7YZU3_DROME", "id": "B7YZU3-1", "name": "Proton-coupled folate transporter", "aln": "----------------------------------------MVEKASNAFTLEKLRNLQWEKVFR------------MFYIEPVVFMLLFSHTLSGTIQRNQVIYQTCTVIFHYNESDCKQLDVKN-------------------------------ASAEINAIETELQPYVANLFLARTLLESIVPAFCGLFIGSWSDHYGR-KPLLIVSMIGFSASFLMMAAICELSSYY--VVNPWWYIMAAVPHSLLGGNCVFSVAAFCFISDITDCKSRPYRMIFMESLFFIGLTSGSLLSSFVYAAVGSAATIGISGCIVTFATLFIIFFVPESLHFHKEQETKNAITANVEKECIDSKVPITACDLQLDRVAIDCPPNFMNDEEPGKDKRMELPTPATPAMSFDDDLLAKYVERLPQKAEERKRQEAEEQAKKAGLFSMVHIRDMISTCFKRRDHHARAIIWLVTLAMFLSIFVFDGVMTVMYLFVREKFHWTVRDYTFFETVS----HLVPMIG---ALIGFLILRKVFRLSVVTLALLAFFSEILNNLAKGFATMPW------HMYLSVTLGVFRSISGPMCRTIVSNIVPPSDLGKIFSIKNVLQSFAPFVAAPLYTLIYKRSLTTYPGLFNFVSSFLYLLSFVFIGYVLRIKYRYKQHYAKVLK-----------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VA14-1", "uniprot_id": "Q9VA14_DROME", "id": "Q9VA14-1", "name": "Proton-coupled folate transporter", "aln": "-----------------------------------------MEKAS----LSQLKTLEWGRLFN------------MFYIEPVLFMLIFSHMLSGTVMRNQLIYQACTVIFQYNETDCKLLDSKN-------------------------------TTTEIQAIETELQDYVANMFLTRTLFESIMPAICGLFVGSWSDQYGR-KPLMIVSLVGFSASALISSIICWLSSYY--MVNPWWYTLAAVPHSVLGGWCVFSVAAFCFITDTTDMKTRPYRMIFMEIILFVALTSGSLLSSFVYAATSSAFVQSLSCLIVIIATLFIIFYLPESLGMSPEEDEIPEKEKNVVVTVLDHKN-----------------------------KTNEISAEAEKTENCDD----------PPKYESPEKP-LEDKVEKAGLFSIKHVKDMFSTCFKKRENNAHTIIWLVTLAGFVSIFVADGVMTVNYLFVRQQFHFTVRDFTIFETFS----QSVPMLG---AVLGILILRKFFGLSVVALALLSLLSEVAANIARGFAYLSW------HLYLSVVLGIFRSIQGPMFRTIVSNIVPPSDTGKLFAIGNILQSFAPFVAAPLYTAIYKESLASNPGGFNFLSAAFYGLAFILIGWVMRIKFKHQKFYAKTLK-----------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "A1Z7R6-1", "uniprot_id": "S46_DROME", "id": "A1Z7R6-1", "name": "Probable peptidoglycan muropeptide transporter SLC46", "aln": "----------------MNEEPHAHENLVAKAQRSGDADPEVASTASEKQRSSGASAIAVGTEFPGNPQASRPQSLGMYLLEPFILILLFAYNFSSTVLKNEVIYQSCTAGFGYPDSVCQLLGTKN-------------------------------ITNETKRIEEQVQPYAAQVTLAMRLVECFIPAFCGLFAGSWADHYGR-KPLLMCSFLGYGLQYLISAAIAYCAMYTQGLVSPWWYVLSIVPLSCLGSSVTYSVAAVCFIADVSGGKVRSYRMIAYELAIYVGLLLGSLGSGYAYEATDAYIVFSISAVCIFTALFLMALLLPESLPARN----------------------------------------------------RTLSTPTTDTS------------------------------------VVSMLKSLWSTCSKPREHQNRFMLTTIMVVLLLTAFVSDGSNSVFYKFMRIKFHWTVKQFTEYETVG----ILVPAVAGSGGVLFIWSLRKCTNSAILWLALVSLLSHCSSSLMKGFALESW------QIYVAIGLGVFKSLVNPMCRTMITNLLPADERGKIFALLGVLQALSPLISSTLYVAIYTRTLNTEPGIFNVFSAFLFGIGIILLGTVWHKKSRNLVYYEPVFK-----------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q8CA03-1", "uniprot_id": "S46A2_MOUSE", "id": "Q8CA03-1", "name": "Solute carrier family 46 member 2", "aln": "--------------------------------------------------MGPGGTCPWSSRLSG------------FRVRTWIEPVVASTQVAGSLYDAGLLLVVKESFKSEAGGSSNYSANQ----------------------------------SLVEYQEDQQQKAISNFNIIYNLVLGLTPLLSAYGLGWLSDRYHR-KISICTAMLGFLLSRIGLLLKVMLDWPVEVMYG------AAALNGLCGSFSAYWSGVMALGSLGCSEGRRSVRLILIDLVLGLAGFSGSMASGHLFKQIVGHSAQGLLLTACSVGCAAFALFYSLFVLKVPE--SKPNKVHPTVDTVSGMMG-----------------------------TYRTLDPDQQDKQ---------------------------------------NVPRNPRTPGKGKSSQREVVALLFVGAIIYDLAAVGTVDVMALFVLKEPLHWNQVQLGYGMASG----YIIFITS----FLGVLVFSRCFRD--TTMIIIGMLSFGSGALLLAFVKETY------MFYIARAIMLFALIPITTIRSAMSKLIKDSSYGKIFVILQLCLTLTGVVTSTIYNKIYQLTLDKFIGTCFVLSSFLSFLAIVPIGVVAYKQVPRSQQGECAEKQRS--------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D4A6S9-1", "uniprot_id": "D4A6S9_RAT", "id": "D4A6S9-1", "name": "", "aln": "--------------------------------------------------MGPGFTCPWSGSLSG------------FRVRTWIEPVVASTQVAGSLYDTGLLLVLKESFASDARDSSNYSANQ----------------------------------SLGERQEDQQQKAISNFYIIYNLVVGLTPLLSAYVLGWLSDRYHR-KISICTAMLGFLLSRIGLLLKVMLDWPLEVMYG------AAALNGLCGGFSAYWSGVMALGSLSCSQSRRSVRLILIDLVLGLAGFCGSMASGHLFKQIVGHSAQGLLLTACSVGCAAFALFYSLFVLKVPEAVSKPNKVHPTVDTVSGMMG-----------------------------TYRTLDPDQQDKP---------------------------------------NIQANPPTPGKEKPSQ-AIIALLFVGAIVYDLAVVGTLDVMALFVLKDPLHWNQVQLGYGMASG----YIIFITS----FLGVLVFSRYFRD--TTMIIIGMVSFGSGALLLAFVKKTY------MFYIARAVMLFALIPITTIRSAMSKLVKDSSYGKIFVILQLCLALTGVVTSTMYNKIYQLTLNKFAGTCFLLSSFLSFLAIVPIGVVAYKQVPGSRQGECADTQRS--------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9BY10-1", "uniprot_id": "S46A2_HUMAN", "id": "Q9BY10-1", "name": "Solute carrier family 46 member 2", "aln": "--------------------------------------------------MSPEVTCPRRGHLPR------------FHPRTWVEPVVASSQVAASLYDAGLLLVVKASYG--TGGSSNHSASP----------------------------------SPRGALEDQQQRAISNFYIIYNLVVGLSPLLSAYGLGWLSDRYHR-KISICMSLLGFLLSRLGLLLKVLLDWPVEVLYG------AAALNGLFGGFSAFWSGVMALGSLGSSEGRRSVRLILIDLMLGLAGFCGSMASGHLFKQMAGHSGQGLILTACSVSCASFALLYSLLVLKVPESVAKPSQELPAVDTVSGTVG-----------------------------TYRTLDPDQLDQQ---------------------------------------YAVGHPPSPGKAKPHK-TTIALLFVGAIIYDLAVVGTVDVIPLFVLREPLGWNQVQVGYGMAAG----YTIFITS----FLGVLVFSRCFRD--TTMIMIGMVSFGSGALLLAFVKETY------MFYIARAVMLFALIPVTTIRSAMSKLIKGSSYGKVFVILQLSLALTGVVTSTLYNKIYQLTMDMFVGSCFALSSFLSFLAIIPISIVAYKQVPLSPYGDIIEK-----------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VY22-1", "uniprot_id": "Q9VY22_DROME", "id": "Q9VY22-1", "name": "Solute carrier family 46 member 3", "aln": "MSPKDGSLGDAKFAKYTVNHEPPPPSAMTTTQSTNSGVDKPIAKEKDNGTTNPPVKRSWREKIRLVAN--------NVTVEPILAAYIMPSVLSNLATQNLNLEKACRVNMAYGDEVCDALTRR--------------------------------QTANYTLEEETVQQMVARMAAWKTVIQSLFPCLLILFWGSWSDRHRRRKPCILIPVVGEFLGVVGLMLCVYFEQAPMEAAALT----EAIFPSLSGGWFTMLMGVFSYIADITTEEDRTLRIGILNVCFSVGVPIGMAFSGVLLKQIGFYGVFSISAAFYVIAFVYGFFFLEEPQSRPEKSAEQ-----------------------------------------------KSLLADFFDKE---------------------------------------HVVQTFRVAFKKGENQRRKRVILLMIVVMVIIGPLHGEMAVTYLFTRFRFNWSEVEFSFFSTYA----MFTGLIG---VIFCVGILSHKLNIDDALVGVLSSTSKILSSFVYAFATLPW------HMYLGGLVEIFNGTAFIAMRSIATKLVSKDELGKVNSLFGVAEALMPMVFAPMYTTLYAATLRVLPGAFFLLGGGLTLFSVFIFLWMYRFQVRQRRNLASADAESAAVKDPNGNINAIEALVLASEAKGQMNGIIANVIHESLEHADPISTPPTNTAQQIERGIENHGFVQEEKVKDRDC", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q8INF8-1", "uniprot_id": "Q8INF8_DROME", "id": "Q8INF8-1", "name": "Solute carrier family 46 member 3", "aln": "---------------------------------MAKPRSSADAAGNGSGAVDAEPKLNYFQKLWRYR--------HYLVIEPFFFFYFMASVFNAVAMQNFPLDKACRVNLGYNKIVCDTMLDKSELGIECDDFDFENTTQGATPDLADLVIGATGFNYTVCKAELEAQILAADVSGKRAPMAAIFPLIVLLFAGGWADRYNKRKPCMIMPIIGEALSFTCQIISSIFFESLPMEFGAY---CEAIVPALFGGLTFCLMAIYSYITIATPEEDRVFRFGIFAMFVTGVPFIGQPISGVLFTTLGYTWSFASAIVFQLIAIFYIIFFIKEVKTTPTTSTTANEPPPLPTSLPPKQQGADN-------------------------MAYETTNLDELQGNKNVN-------FQLTPQMEPKVEVVPPKRSLLKELFDPTLVLDCIRFPLVKRPNNGRMLLILLLCAYFLTVGPTSGENDYWYRFTLKKLAWNGNDFSIYLTLS----SGAALVG---TFIGTAILSKLLKVSDSMIGMLSALSIVCSRVLFAFSSSTA------SFYVAGVVDMFVSLRVIAIKTIGSSIVAGDELSKMYSIFGISEPIAQFIFPPIFSEIYKSTVDSFPGAIWLFGEIFYIPNVLVFVVCYFLLRRRKANEEKSVVEMEQNGGANGGNRASVVPDSEITSL----------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q0E8E1-1", "uniprot_id": "Q0E8E1_DROME", "id": "Q0E8E1-1", "name": "Proton-coupled folate transporter", "aln": "----------MSVTGAHSENAAQRRNSRSSENSEDNENSASGTVREQRDEAAGRTVLQWAWHVVKS-----------TSVEPTMFLYMFAFMITSVVEQNFFLYKSCRVNRNFTEEICRNLNKP-----------------------------------ENEEFRTKAMLTNAWFLQWENISAHVFPIILALFLGSFSDRRGR-KLPLLMGLVGKFFYSTMIVVNARMTTWPVQNIIYS----ATLPSALTGADVAIFASCFAYISDISSLQQRTIRVTILDVIYLSAMPMGVALGSHLFYNVFNQSYADMFTVNASLLALAIIYTLCALKWQTTPRQRSLRELG-----------------------------------------CCGFWGDFFDKQ---------------------------------------HVKDSLAVLVKPRKGHRRSFLIILLVSMALYTFQRD-EGQYLYMYTLGKFDWDVSAYSNFKTFK----SSAYVIA---MLLAVPLMNKILGWRDTTIIFIGTWAHSIARLFFYFATNTD------LLYAGAVVCSLGPIVGPMIRAMTSKIVPTSERGKVFALLSVCDNAVPFISGVCYSQLYRRTQNTNHGGNVFILTIATQIAVFVMILCLHIVLGKNSLAVPEVPEKESGLISQTEAVLEAEIEEHKN------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P46996-1", "uniprot_id": "YJQ3_YEAST", "id": "P46996-1", "name": "Uncharacterized membrane protein YJL163C", "aln": "------MSNEDETTRLMSSDEMDYLLETAGINALEEIISQNDSTGINLDTNETAQDSSYDSIRRS------------PSILSVAKSVEGEHGRRKLLCLYGLVMIICIAESISMTATIPLVMDKVAEG---------------------------ISDENGHYDSVAVQTIVSSISSSTMMIAGAISIFMAGKWGELSDRIGRVRVFKYMSGIRVIGLLTHVFTLSSKMKYHKWAIVLT-----ACIVPSFGGLFALVANGNSYVSDIVKTEHRMVTIGIMMSCIYATMGVGPMFGSFLVKWTHGNGFIPIYTSIAFVILALIICETIMVEPRHETQMAHSQSTYTKRREKLRSQSGSDD-----------------------ARNYQSVTYGKFQIMRLMD--------------------------------LLAPVKKLWLKPDSAGSLVPRHTVILLIVLDILFVCGTTSCMPALILFSTYEYKWHAVELGYFISILGIGRGVVLLVVSPTLLYTLKRIYQHLNHSIDKIDIFCIQFSMIVITLSLFVMIRFGEKTPTSMIIFALLQALSAFCSPTLQSGIIKYTSKKHTGEMFGAMALVRSCVMLVIPPILLKLYGSTVSVNPSLFMYIP---FSTSIVAILLTFFLRIYKNPPLDGP-------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . : : . . : * :*: : : : *. . : * . * .. . : : . : : : .. * : : : :: . . .:: : .: :* : . . .. : ", "identical_positions": 7, "similar_positions": 46, "identity": "0.94%" }, { "cls_id": "homologset.agr.MGI:1353620", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D4A6B3-1", "uniprot_id": "D4A6B3_RAT", "id": "D4A6B3-1", "name": "", "aln": "MAVSRAPAHDSARQRMVWLFP---LVFCLGTGSDVPQSSSNPRLMNGILGESIVLPLELPAGKIASVIVWSHKEALQGTIMFIIQLKEPEKPNIINANREKEKRLNITQSYSLQLNNLTMADTGSYTAQITTEDTEPTIFRYTLRVFERLSNLEIANHTLLLENGTCQMYLACTVKNSNQTVSFEWQTTGNISLREPNVTISWDPRNSSNQTYICRAENAVSNLSVSVSTQSLCK-DLTNQPWTKAQLTAIISIPMVVVIPVFLYMCIYLWKRRRGSLPLTRQHPDSSQSSD------TPGSPGNTVYAQVSHPMQEMKIQNPIKNDSMTIYSIVNHSRE----------PVSPRLNTLKDIK-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9ET39-1", "uniprot_id": "SLAF6_MOUSE", "id": "Q9ET39-1", "name": "SLAM family member 6", "aln": "MAVSRAPAPDSACQRMVWLFP---LVFCLGSGSEVSQSSSDPQLMNGVLGESAVLPLKLPAGKIANIIIWNYEWEASQVTALVINLSNPESPQIMNT--DVKKRLNITQSYSLQISNLTMADTGSYTAQITTKDSEVITFKYILRVFERLGNLETTNYTLLLENGTCQIHLACVLKNQSQTVSVEWQATGNISLGGPNVTIFWDPRNSGDQTYVCRAKNAVSNLSVSVSTQSLCKGVLTNPPWNAVWFMTTISI-ISAVILIFVCWSIHVWKRR-GSLPLTSQHPESSQSTD------GPGSPGNTVYAQVTRPMQEMKIPKPIKNDSMTIYSIVNHSREETVALTGYNQPITLKVNTLINYNS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q96DU3-1", "uniprot_id": "SLAF6_HUMAN", "id": "Q96DU3-1", "name": "SLAM family member 6", "aln": "---------------MLWLFQSLLFVFCFGPGNVVSQSSLTPLMVNGILGESVTLPLEFPAGEKVNFITWLFN----ETSLAFIVPHETKSPEIHVTNPKQGKRLNFTQSYSLQLSNLKMEDTGSYRAQISTKTS-AKLSSYTLRILRQLRNIQVTNHSQLFQNMTCELHLTCSVEDADDNVSFRWEALGNTLSSQPNLTVSWDPRISSEQDYTCIAENAVSNLSFSVSAQKLCEDVKIQYTDTKMILFMVSGI---CIVFGFIILLLLVLRKRRDSLSLSTQRTQGPAESARNLEYVSVSPTNNTVYASVTHSNRETEIWTPRENDTITIYSTINHSKE--------SKPTFSRATALDNVV-", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *:*** :***:*.*. *.*** * ::**:**** .***::***: ...* * .: . .* :.:.*:* : . ****:*******:.**.* ***** ***:*: : * **::.:* *:: :*:: *::* **:::*:* ::: .:.**..*:: ** **:*: **** *.:* * * *:*******.***:*.**: : . . : .* :: *: : : ::* .**.*: *:.:.. .: ....*****.*::. :* :* .* :**::**** :***:* * : .:* : ", "identical_positions": 124, "similar_positions": 110, "identity": "34.07%" }, { "cls_id": "homologset.agr.MGI:1353621", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9EPU7-1", "uniprot_id": "Z354C_RAT", "id": "Q9EPU7-1", "name": "Zinc finger protein 354C", "aln": "MAVDLLAARGTEPVTFRDVAVSFSQDEWLHLDPAQRTLYREVMLENYSNLASLGFQASIPPVIGKLQKGQDPCM-EREAPEDTCLDFQIQSEIEASSPEQDVFIEGPSRGLLKNRSTKCAYWKISFGELVKYERLETAQEQEKKAHEPGAASPKEVTSEDGIPTDPELEKPLFMNKALVSQETDPIERVPGMYHTSEKDLPQDFDLMRNFQIYPGQKPYVCSECGKGFSQSLHLLEHKRIHTGEKPYKCSECGKSFSHRSSLLAHQRTHTGEKPYKCSECEKAFGSSSTLIKHLRVHTGEKPYRCRECGKAFSQCSTLTVHQRIHTGEKLYKCAECDKAFNCRAKLHRHQRIHTGEKPYKCAECGKGYSQFPSLAEHQRLHTGGQLCQCLQCGRTFTRVSTLIEHQRIHTGQKPYQCNECGKTFNQYSSFNEHRKIHTGEKLYTCEECGKAFGCKSNLYRHQRIHTGEKPYQCNQCGKAFSQYSFLTEHERIHTGEKLYKCMECGKAYSYRSNLCRHKKVHLKERLYKWKEYGTPFMYGSSLAPHQRCLKGEKPEDLNSSL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q571J5-1", "uniprot_id": "Z354C_MOUSE", "id": "Q571J5-1", "name": "Zinc finger protein 354C", "aln": "MAVDLLAARGTEPVTFRDVAVSFSQDEWLHLDPAQRSLYREVMLENYSNLASLGFQASIPPVIGKLQKGQDPCM-EREAPEDTCLDFEIWPEIEALPPKQDVLTKETSHGLIKNGSTKCVYWKISFGELVKTECRDIAQEQEKKVHGPGAESPKETTSEDGTPTGFEPEKPLFISKALVSQEGDPTESVPATYHTSEKDLPQDFDLMRSFQMYPGQKPHVCSECGKGFTQSLHLLEHKRLHTGEKPYKCSECGKSFSHRSSLLAHQRTHTGEKPYKCSECEKAFGSSSTLIKHLRVHTGEKPYRCRQCGKAFSQCSTLTVHQRIHTGEKLYKCAECDKAFNCRAKLHRHQRIHTGEKPYKCAECGKGYSQFPSLAEHQRLHTGEQLCQCLQCGRTFTRVSTLIEHQRIHTGQKPYQCNECGKTFNQYSSFNEHRKIHTGEKLYTCEECGKAFGCKSNLYRHQRIHTGEKPYQCNQCGKAFSQYSFLTEHERIHTGEKLYKCMECGKAYSYRSNLCRHKKVHLKERLYKWKEYGTPFIYGSSLTPYQKFLKGDKPENFNSSL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q86Y25-1", "uniprot_id": "Z354C_HUMAN", "id": "Q86Y25-1", "name": "Zinc finger protein 354C", "aln": "MAVDLLSAQ--EPVTFRDVAVFFSQDEWLHLDSAQRALYREVMLENYSSLVSLGIPFSMPKLIHQLQQGEDPCMVEREVPSDTRLGFKTWLETEALPHRQDIFIEETSQGMVKKESIKDGHWDINFEEAVEFES-EIEEEQEKKPLRQMIDSHEKTISEDGNHTSLELGKSLFTNTALVTQQSVPIERIPNMYYTFGKDFKQNFDLMKCFQIYPGGKPHICNECGKSFKQNLHLIEHQRIHTGEKPYKCNECEKTFSHRSSLLSHQRIHTGEKPYKCNECEKAFSNSSTLIKHLRVHTGEKPYRCRECGKAFSQCSTLTVHQRIHTGEKLYKCGECEKAFNCRAKLHRHQRIHTGEKPYKCSECGKGYSQFTSLAEHQRFHTGEQLYTCLECGRTFTRIVTLIEHQRIHTGQKPYQCNECEKAFNQYSSFNEHRKIHTGEKLYTCEECGKAFGCKSNLYRHQRIHTGEKPYQCNQCGKAFSQYSFLTEHERIHTGEKLYKCMECGKAYSYRSNLCRHKKVHTKEKLYKWKEYGKPFICSSSLTQYQRFFKGDKAYEV----", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "******:*: ********** **********.***:***********.*.***: *:* :* :**:*:**** ***.*.** *.*: * ** . .**:: : .*:*::*: * * :*.*.* * *: * : :***** * ::. **** *. * *.** ..***:*: * * :* *:* **: *:****: **:*** **::*.****.*.*.***:**:*:*********.** *:********:*** *********.******..********************:**************************.**:************************:*********.*******:*** ** **:*******: ******************** *:************************************************************************************************** **:********.**: .***: :*: :**:*. :. ", "identical_positions": 408, "similar_positions": 83, "identity": "72.73%" }, { "cls_id": "homologset.agr.MGI:1353623", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P50636-1", "uniprot_id": "RN19A_MOUSE", "id": "P50636-1", "name": "E3 ubiquitin-protein ligase RNF19A", "aln": "--------------MQ--EQEISFIFKYNEG-----------LCMNIDSD---------------------------------SILMSILDMSLHQ-QMGSDRDLQSSTSSVSLPSVKKAPKQRRISIGSLFRRKKDS--KRKSRELNGGVDGIASIESIHSEMCADKNSIFSTNTS----SDNGLTSISKQIGDFIECPLCLLRHSKDRFPDIMTCHHRSCVDCLRQYLRIEISESRVNISCPECTERFNPHDIRLILSDDVLMEKYEEFMLRRWLVADPDCRWCPAPDCGYAVIAFGCASCPKLTCGREGCGTEFCYHCKQIWHPNQTCDAARQERAQSLRLRTIRSSSISYSQESGAAADDIKPCPRCAAYIIKMNDGSCNHMTCAVCGCEFCWLCMKEISDLHYLSPSGCTFWGKKPWSRKKKILWQLGTLVGAPVGIALIAGIAIPAMIIGIPVYVGRKIHNRYEGKDVSKHKRNLAIAGGVTLSVIVSPVVAAVTVGIGVPIMLAYVYGVVPISLCRSGGCGVSAGNGKGVRIEFDDENDINVGGTNAAIDTTSVAEARHNPSIGEGSVGGLTGSLSASGSHMDRIGTIRDNLSETASTMALAGASITGSLSGSAMVNCFNRLEVQADVQKERCSLSGESGTVSLGTVSDNASTKAMAGSILNSYIPLD---------------------REGNSMEVQVDIESKPFKFRHNSGSSSVDDSGATRGHTGGASSG-LPEGKSSATKWSKEATG------GKKSKSGKLRKK-GNMKINETREDMDAQLLEQQSTNSSEFEAPSLSDSMPSVADSHSSHFSEFSCSDLESMRTSCSHGSSDCHARFTAVNTLPEVENDRLENSPHQCSS---ALLSKAASCSDVPQPSHAADEHGTSRSGGKPMVDLCFGDALRETNNNHSHQTADLK-VAVQTEI", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0ABK0LLQ3-1", "uniprot_id": "A0ABK0LLQ3_RAT", "id": "A0ABK0LLQ3-1", "name": "RBR-type E3 ubiquitin transferase", "aln": "--------------MQ--EQEISFIFKYNEG-----------LCMNIDSD---------------------------------SVLMSILDMSLHQ-QMGSDRDLQSSASSVSLPSVKKAPKKRRISIGSLFRRKKDN--KRKSRELTGGVDGIASIESIRSEVCAEKNSIFSTNAS----SDNGLTSISKQIGDFIECPLCLLRHSKDRFPDIMTCHHRSCVDCLRQYLRIEISESRVNISCPECTERFNPHDIRLILSDDVLMEKYEEFMLRRWLVADPDCRWCPAPDCGYAVIAFGCASCPKLTCGREGCGTEFCYHCKQIWHPNQTCDAARQERAQSLRLRTIRSSSISYSQESGAAADDIKPCPRCAAYIIKMNDGSCNHMTCAVCGCEFCWLCMKEISDLHYLSPSGCTFWGKKPWSRKKKILWQLGTLVGAPVGIALIAGIAIPAMIIGIPVYVGRKIHNRYEGKDVSKHKRNLAIAGGVTLSVIVSPVVAAVTVGIGVPIMLAYVYGVVPISLCRSGGCGVSAGNGKGVRIEFDDENDINVGGTNTAIDTTSVAEARHNPSIGEGSVGGLTGSLSASGSHMDRIGTMRDNLSETASTMALAGASITGSLSGSAMVNCFNRLEVQADVQKERCSLSGESGTVSLGTVSDNASTKAMAGSILNSYIPLDRITTFTLTQRFFIVVTWIRREREGNSMEVQVDIESKPFKFRHHSGSSSVDDGGAARGHASGSSSG-LPEGKSSATKWSKEATG------GKKSKSGKLRKK-GNTKINETREDMDAQLLEQQSTNSSEFEAPSLSDSMPSVADSHSSHFSEFSCSDLESMRTSCSHGSSDCHARFTAVNTLPEVENDRLENSPHQCSG---SLLSKTASCSEVPQPSHAADERATSSGGGKAAVDVCFGDALRETNNNHSHQAADLK-VAVQTEI", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9NV58-1", "uniprot_id": "RN19A_HUMAN", "id": "Q9NV58-1", "name": "E3 ubiquitin-protein ligase RNF19A", "aln": "--------------MQ--EQEIGFISKYNEG-----------LCVNTDPV---------------------------------SILTSILDMSLHR-QMGSDRDLQSSASSVSLPSVKKAPKKRRISIGSLFRRKKDN--KRKSRELNGGVDGIASIESIHSEMCTDKNSIFSTNTS----SDNGLTSISKQIGDFIECPLCLLRHSKDRFPDIMTCHHRSCVDCLRQYLRIEISESRVNISCPECTERFNPHDIRLILSDDVLMEKYEEFMLRRWLVADPDCRWCPAPDCGYAVIAFGCASCPKLTCGREGCGTEFCYHCKQIWHPNQTCDAARQERAQSLRLRTIRSSSISYSQESGAAADDIKPCPRCAAYIIKMNDGSCNHMTCAVCGCEFCWLCMKEISDLHYLSPSGCTFWGKKPWSRKKKILWQLGTLVGAPVGIALIAGIAIPAMIIGIPVYVGRKIHNRYEGKDVSKHKRNLAIAGGVTLSVIVSPVVAAVTVGIGVPIMLAYVYGVVPISLCRSGGCGVSAGNGKGVRIEFDDENDINVGGTNTAVDTTSVAEARHNPSIGEGSVGGLTGSLSASGSHMDRIGAIRDNLSETASTMALAGASITGSLSGSAMVNCFNRLEVQADVQKERYSLSGESGTVSLGTVSDNASTKAMAGSILNSYIPLD---------------------KEGNSMEVQVDIESKPSKFRHNSGSSSVDDGSATRSHAGGSSSG-LPEGKSSATKWSKEATA------GKKSKSGKLRKK-GNMKINETREDMDAQLLEQQSTNSSEFEAPSLSDSMPSVADSHSSHFSEFSCSDLESMKTSCSHGSSDYHTRFATVNILPEVENDRLENSPHQCSI---SVVTQTASCSEVSQLNHIAEEHGNN--GIKPNVDLYFGDALKETNNNHSHQTMELK-VAIQTEI", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "E7F0K2-1", "uniprot_id": "E7F0K2_DANRE", "id": "E7F0K2-1", "name": "RBR-type E3 ubiquitin transferase", "aln": "MKCFYADDLKDQVEIQPGDSKLTRVSQLELPGSREQLAESSPPCLNTSRSPLKTLSPLPSLSPPSPSSSSSPSLPVDTSQSFGNHSASFGEMSLHQQQQGSERDLPSAASSVSLPSVRKTPKKRRISLRSLFRRRCGDPKSRKSRALAAGVDGIASVESVHSEMCQQQDHASALSAAGVAYTSSSCSSSSGSTSELLECPLCLLRHTRDRFPDIMTCHHRSCADCLRQYLRIEISESRVNISCPECSERFNPHDIRMILNDRVLMEKYEEFMLRRWLVADPDCRWCPAPDCGYAVIAFGCASCPKITCGRDGCGTEFCYHCKQLWHPNQTCDAARQQRAQSLRLRPFRSSSLSYSQESGAAADDIKPCPRCAAYIIKMNDGSCNHMTCAVCGCEFCWLCMKEISDLHYLSPSGCTFWGKKPWSRKKKILWQLGTLVGAPVGIALIAGIAIPAMIIGIPVYVGRKIHNRYEGKDISKHKRNLVIAGGVTLSVIVSPVVAAVTVGIGVPIMLAYVYGVVPISLCRSGGCGVSAGNGKGVRIEFDDENDMNPGTGAAVTDTTSVAETRQNPSIGEGSVGGLTGSLSASGSHMERIGAMRDNLSENASTMALAGASITGSLSGSAMVNCFNRLEVQADVQKERCSLSGESGTVSLGTISDNASTKAMAGSILNAYLPMD---------------------RDGNSVEVQVDVESKRGKLRHHSGSSSMDDGSSGGPGASACPSGCLHDGKCVTSRWAKEPSSTSSSSSGKKSK-GKLRKKSGGTKINETREDMDAQLLERRSTNSSELDSPSLSGSLPSVADSHSSHFSEFSCSDLDACRPTCYESHIRHPNTGGAVSPLPEVENDRLENCPASGSLPQAMVAPISPDGAAERPLCYIAEENVSLMCAANASQ-----SSPKERNNNLPQPASPVRNTCIQTEI", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :* :.:: : : : *:* . . *: :****: * **:*** *::********:*:**:****: *****: .. .**** * .*******:**::**:* ::: : .:: :... :* * . .:::*********::**************.***********************:*********:**.* *******************************************:****:************:************:********.:****:*************************************************************************************************************************:*******.****************************************************************:* * :. *******:*:***********************:***::******.************************************* *************:***************:*:*:* ::***:*****:*** *:**:*****:**..: :....** * :**. :::*:**.:. ***** ****** *. ***************::******:::****.*:*******************:: :.:* .. :*. ***********.* . * : . :.. : : *:*. . . :. .: :* *** .: : :: ..:****", "identical_positions": 608, "similar_positions": 142, "identity": "64.68%" }, { "cls_id": "homologset.agr.MGI:1353624", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9R0R3-1", "uniprot_id": "APEL_RAT", "id": "Q9R0R3-1", "name": "Apelin", "aln": "MNLSFCVQALLLLWLSLTAVCGVPLMLPPDGKGLEE-GNMRYLVKPRTSRTGPGAWQGGRRKFRRQRPRLSHKGPMPF", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9R0R4-1", "uniprot_id": "APEL_MOUSE", "id": "Q9R0R4-1", "name": "Apelin", "aln": "MNLRLCVQALLLLWLSLTAVCGVPLMLPPDGTGLEE-GSMRYLVKPRTSRTGPGAWQGGRRKFRRQRPRLSHKGPMPF", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9ULZ1-1", "uniprot_id": "APEL_HUMAN", "id": "Q9ULZ1-1", "name": "Apelin", "aln": "MNLRLCVQALLLLWLSLTAVCGGSLMPLPDGNGLED-GNVRHLVQPRGSRNGPGPWQGGRRKFRRQRPRLSHKGPMPF", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q4TTN8-1", "uniprot_id": "APEL_DANRE", "id": "Q4TTN8-1", "name": "Apelin", "aln": "MNVKILTLVIVLVVSLLCSASAGPMASTEHSKEIEEVGSMRTPLRQNPARAGRSQRPAGWRR-RRPRPRLSHKGPMPF", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "**: : . .::*: * :... .: ... :*: *.:* :: . :* * . .* *: ** ************", "identical_positions": 25, "similar_positions": 27, "identity": "32.05%" }, { "cls_id": "homologset.agr.MGI:1353627", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9R182-1", "uniprot_id": "ANGL3_MOUSE", "id": "Q9R182-1", "name": "Angiopoietin-related protein 3", "aln": "MHTIKLFLFVVPLVIASRVDPDLSSFDS------APSEPKSRFAMLDDVKILANGLLQLGHGLKDFVHKTKGQINDIFQKLNIFDQSFYDLSLRTNEIKEEEKELRRTTSTLQVKNEEVKNMSVELNSKLESLLEEKTALQHKVRALEEQLTNLILSPAGAQEHPEVTSLKSFVEQQDNSIRELLQSVEEQYKQLSQQHMQIKEIEKQLRKTGIQEPSENSLSSKSRAPRTTPPLQLNETENTE-QDDLPADCSAVYNRGEHTSGVYTIKPRNSQGFNVYCDTQSGS-PWTLIQHRK---DGSQDFNETWENYEKGFGRLDGEFWLGLEKIYAIVQQSNYILRLELQDWKDSKHYVEY-SFHLGSHETNYTLHVA-EIAGNIPGALPEHTDLMFST----WNHRAKGQLYCPESYSGGWWWNDICGENNLNGKYNKPRTKSRPERRRGIYWRPQSRKLYAIKSSKMMLQPTT----------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "F7FHP0-1", "uniprot_id": "F7FHP0_RAT", "id": "F7FHP0-1", "name": "Angiopoietin-related protein 3", "aln": "MHTIKLLLFVVPLVISSRVDPDLSPFDS------VPSEPKSRFAMLDDVKILANGLLQLGHGLKDFVHKTKGQINDIFQKLNIFDQCFYDLSLQTNEIKEEEKELRRTTSKLQVKNEEVKNMSLELNSKLESLLEEKMALQHRVRALEEQLTSLVQNPPGAREHPEVTSLKSFVEQQDNSIRELLQSVEEQYKQLSQQHIQIKEIENQLRKTGIQEPTENSLYSKPRAPRTTPPLHLKEAKNIE-QDDLPADCSAIYNRGEHTSGVYTIRPSSSQVFNVYCDTQSGT-PRTLIQHRK---DGSQNFNQTWENYEKGFGRLDGEFWLGLEKIYAIVKQSNYILRLELQDWKDSKHYAEY-SFHLGNHETNYTLHVA-EIAANIPEALPEHRDLMFST----WDHRAKGQLYCPESYSGGWWFSDMCGENNLNGKYNKPRAKSKPERRRGISWRPRGGKLYSIKSSKMMLQPTT----------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9Y5C1-1", "uniprot_id": "ANGL3_HUMAN", "id": "Q9Y5C1-1", "name": "Angiopoietin-related protein 3", "aln": "MFTIKLLLFIVPLVISSRIDQDNSSFDS------LSPEPKSRFAMLDDVKILANGLLQLGHGLKDFVHKTKGQINDIFQKLNIFDQSFYDLSLQTSEIKEEEKELRRTTYKLQVKNEEVKNMSLELNSKLESLLEEKILLQQKVKYLEEQLTNLIQNQPETPEHPEVTSLKTFVEKQDNSIKDLLQTVEDQYKQLNQQHSQIKEIENQLRRTSIQEPTEISLSSKPRAPRTTPFLQLNEIRNVK-HDGIPAECTTIYNRGEHTSGMYAIRPSNSQVFHVYCDVISGS-PWTLIQHRI---DGSQNFNETWENYKYGFGRLDGEFWLGLEKIYSIVKQSNYVLRIELEDWKDNKHYIEY-SFYLGNHETNYTLHLV-AITGNVPNAIPENKDLVFST----WDHKAKGHFNCPEGYSGGWWWHDECGENNLNGKYNKPRAKSKPERRRGLSWKSQNGRLYSIKSTKMLIHPTDSESFE-----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8N7UZN6-1", "uniprot_id": "A0A8N7UZN6_DANRE", "id": "A0A8N7UZN6-1", "name": "Angiopoietin-related protein 3", "aln": "MLMLILLLWLSLSTTSAAPNSKKSPTEAPILITAPPTEARSRFAMLDDVRLLANGLLQLGQSLREFVHKTKSQINDIFQKLNIFDRSFYQLSVVTSEIKEEEEKLKETTIFLKANNEEIRNLSLEINSKINNILQERSQLHTKVGGLEEKLKGLSQSMMPLEQLQEITALKDVIETQERTITDLLRSVKEQHDQLNYQKIKIKSLEDKVNYDTFQDTIEKPMDLNPETPDPFRYLTTNSTNGTKDINDFPADCSEVFTRGQKTSGIYPIKPNQSEPFYVYCEITPDG-AATVIQRRE---DGSVDFDQSWEKYEHGFGKLEKEFWLGLAKIHSIAQQGEYILHIELEDWKEEKRFIEY-TFTLEGPASDYALHLA-PLSGDLSDAMSNHTGMKFSTKD--RDNDNHDESNCARNYTGGWWF-DACGDTNLNGRYAWMRSKARHQRRKGIYWRPSKGSSYTLKSTKITIRPSTQFQ-------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VF34-1", "uniprot_id": "Q9VF34_DROME", "id": "Q9VF34-1", "name": "Fibrinogen C-terminal domain-containing protein", "aln": "MMKFSLLFLLAWSCVFLGSTGSLNRIGN----------SDIGFKSLEELVLIRKTLAAQALKLRGLEIN----LHRVLSKVVLLADAVVQVPGR-----------------YSSKEDPLAVLSERLNLLLERLNQEE-RISTNLLELKEWSTKVCQEPS-----PSQTLPKELTEEKDEPKVDFYQPAKSDCHELDEG---------------------------VRVDGVYRFLVPERNEVQR----------DLYER--------------------YCAFATDGPAWTVIQSRGGSFDPHENFNRSWDEYRAGFGNLSRDFWFGNEFAHKILYRDDHELRIELQEAGEPLDWAEYPLFWLDSESYNYQLSVAGEFRGSLPDALEQHNRMDFSTYDRRRNHAKSADSTCGEDYGGGWWF-DRCTQCNLNGEHG-----VHQRASPAIIWMNWRTGTDKPKSSRMMIRPVNPTPGDNSDGD", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* : *:: : . . . * *::: :: : * . *: : : :: ::.*: :: .. ::. . ::: : :* .:* :: : :*. : .: *:* . : . . * * . * ::.. :: :..:.: .:*. .. * : . . :: * ** .. . *:** * * :*:.:*::*. ***.*. :**:* : * :.:: *::**:: : : ** * * . :* * :. : ..:. *: :: : *** :: . * ..* ****: * * : ****.: : . .: * **::: ::* ", "identical_positions": 65, "similar_positions": 131, "identity": "13.49%" }, { "cls_id": "homologset.agr.MGI:1353631", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D4ADL5-1", "uniprot_id": "D4ADL5_RAT", "id": "D4ADL5-1", "name": "tRNA-specific adenosine deaminase 1", "aln": "-----MWTADEIAQLCYAHY-IKLPKQGKPEPNREWTLLAAVVKIQTPANQACDTPDKQIQVTKEVVSMGTGTKCIGQSKMRESGDILNDSHAEVIARRSFQRYILHQLHVAAVLKEDSIFLPGTQRGLWRLRPDLSFVFFSSHTPCGDASIIPKLEFEEQPCCPVIRNWANNSPGEGSETLEGSRNKRSCEGPDSPVAKKKRLG--TPAGSLSDCVAHH---GAQESGPAKPDASSSGLTKEELDAVNGTASGSFKVVDIYRTGAKCVPGETGDLRKPGAAYHQVGLLRVKPGRGDRTCSMSCSDKMARWNVLGCQGALLMHFLEKPIYLSAVVIGQCPYSQEAMRRALTGRCQETLVLPRGFEVQELKIQQS-SLLFEQSRCAVHRKRGDSPGRLVPCGAAISWSAVPQQ--PLDVTANGFPQGTTKKEIGSPRARSRISKVELFRSFQKLLSCIAE-DERPDSVRVQK-LDTYQEYKEAASAYQEAWSALRRVQPFSSWIRNPPNYHQFK-----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9JHI2-1", "uniprot_id": "ADAT1_MOUSE", "id": "Q9JHI2-1", "name": "tRNA-specific adenosine deaminase 1", "aln": "-----MWTADEIAQLCYAHYNVRLPKQGKPEPNREWTLLAAVVKIQASANQACDIPEKEVQVTKEVVSMGTGTKCIGQSKMRESGDILNDSHAEIIARRSFQRYLLHQLHLAAVLKEDSIFVPGTQRGLWRLRPDLSFVFFSSHTPCGDASIIPMLEFEEQPCCPVIRSWANNSPVQETENLEDSKDKRNCEDPASPVAKKMRLG--TPARSLSNCVAHH---GTQESGPVKPDVSSSDLTKEEPDAANGIASGSFRVVDVYRTGAKCVPGETGDLREPGAAYHQVGLLRVKPGRGDRTCSMSCSDKMARWNVLGCQGALLMHFLEKPIYLSAVVIGKCPYSQEAMRRALTGRCEETLVLPRGFGVQELEIQQS-GLLFEQSRCAVHRKRGDSPGRLVPCGAAISWSAVPQQ--PLDVTANGFPQGTTKKEIGSPRARSRISKVELFRSFQKLLSSIAD-DEQPDSIRVTKKLDTYQEYKDAASAYQEAWGALRRIQPFASWIRNPPDYHQFK-----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9BUB4-1", "uniprot_id": "ADAT1_HUMAN", "id": "Q9BUB4-1", "name": "tRNA-specific adenosine deaminase 1", "aln": "-----MWTADEIAQLCYEHYGIRLPKKGKPEPNHEWTLLAAVVKIQSPADKACDTPDKPVQVTKEVVSMGTGTKCIGQSKMRKNGDILNDSHAEVIARRSFQRYLLHQLQLAATLKEDSIFVPGTQKGVWKLRRDLIFVFFSSHTPCGDASIIPMLEFEDQPCCPVFRNWAHNSSVEASSNLEAPGNERKCEDPDSPVTKKMRLEPGTAAREVTNGAAHHQSFGKQKSGPISPGIHSCDLTVEGLATVTRIAPGSAKVIDVYRTGAKCVPGEAGDSGKPGAAFHQVGLLRVKPGRGDRTRSMSCSDKMARWNVLGCQGALLMHLLEEPIYLSAVVIGKCPYSQEAMQRALIGRCQNVSALPKGFGVQELKILQS-DLLFEQSRSAVQAKRADSPGRLVPCGAAISWSAVPEQ--PLDVTANGFPQGTTKKTIGSLQARSQISKVELFRSFQKLLSRIAR-DKWPHSLRVQK-LDTYQEYKEAASSYQEAWSTLR-KQVFGSWIRNPPDYHQFK-----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9V3R6-1", "uniprot_id": "ADAT1_DROME", "id": "Q9V3R6-1", "name": "tRNA-specific adenosine deaminase 1", "aln": "MCDNKKPTVKEIAELCLKKF-ESLPKTGKPTAN-QWTILAGIVEFNR-NTEAC-----------QLVSLGCGTKCIGESKLCPNGLILNDSHAEVLARRGFLRFLYQEL------KQDRIFHWNSTLSTYDMDEHVEFHFLSTQTPCGDACILE----EEQ---PAAR------------------------------AKRQRLD--------------------EDS-------------------------------EMVYTGAKLISDLSDD-----PMLQTPGALRTKPGRGERTLSMSCSDKIARWNVIGVQGALLDVLISKPIYFSSLNFCCDDAQLESLERAIFKRFDCRTFKHTRFQPQRPQINIDPGIRFEFS------QRSD----WQPSPNGLIWSQVPEELRPYEISVNGKRQGVTKKKMKTSQAALAISKYKLFLTFLELVKFNPKLSEMFDQQLSDPERIAYASCKDLARDYQFAWREIK-EKYFLQWTKKPHELLDFNPMSNK", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *..***:** :: *** *** .* :**:**.:*::: :** ::**:* ******:**: .* ********::***.* *:: ::* *:* ** .: . : : .: * *:*::******.*: *:* *. * :*: ** :.* :: **** :.. :.* . : * **.*****:** *******:*****:* ***** ::.:***:*:: : . *::.**: * : * *. :* . .: ** * :*.* *. .: ** **:: * :::.** **.*** : : :* *** :** :* :*:. . .: .. :* . *: * ** ** :: : * .* ::* : :*: ", "identical_positions": 149, "similar_positions": 115, "identity": "28.76%" }, { "cls_id": "homologset.agr.MGI:1353633", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P56959-1", "uniprot_id": "FUS_MOUSE", "id": "P56959-1", "name": "RNA-binding protein FUS", "aln": "MASNDYTQQATQSYGAYPTQPGQGYSQQSSQPYGQQSYSGYGQSADTS--GYGQSSYGSSYGQTQNTGYGTQSAPQGYG------STGGYG-SSQS--SQSS-YGQQSSYPGYGQQPAPSSTSGSYGGSSQSSSYGQPQ-------------SGGYG----QQSGYGG---QQQSYGQQQSSYNP--------PQGYGQQNQYNSSSGGGGGGGGG-NYGQDQSSMSGGGG-GGGYGNQDQSGGGGGGYGGGQQDRGGRGRGG--------GGGYNRSSGGYEPRGRGGGRGGRGGMGGSDRGGFNKFGGPRDQ--GSRHDSEQDNSDNNTIFVQGLGENVTIESVADYFKQIGIIKTNKKTGQPMINLYTDRETGKLKGEATVSFDDPPSAKAAIDWFDGKEFSGNPIKVSFATRRADFNRGGGNG--RGGRGRGGPMGRGGYGGGGSGGGGRGG------------FPSGGGGG----GG--QQRAGDWKCPNPTCENMNFSWRNECNQCKAPKPDGPGGGPGGSHMGGNYGDDRRG-RGGYDRGGYRGRGG------DRGGFRGGRGGGDRGGFGPGKMDS--------RGEHRQDRRE------------RPY--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0ABK0LB76-1", "uniprot_id": "A0ABK0LB76_RAT", "id": "A0ABK0LB76-1", "name": "RanBP2-type domain-containing protein", "aln": "MASNDYTQQATQSYGAYPTQPGQGYSQQSNQPYGQQSYSGYGQSADTS--GYGQSSYGSSYEQTQNTGYGTQSAPQGYG------STGGYG-SSQS--SQSS-YGQQSSYPGYGQQPAPSSTSGSYGGSSQSSSYGQPQ-------------SGGYG----QQSGYGG---QQQSYGQQQSSYNP--------PQGYGQQNQYN-----------------------------------------------------------------------------------------------------------------SRH-------------------------------------------------------------------------------------------------------------------------------------------------------GGGGG----GG--QQRAGDWKCPNPTCENMNFSWRSECNQCKAPKPDGPGGGPGGSHMGGNYGDDRHG-RGGYDRGSYRGRGG------DRGGFRGGRGGGDRGGFGPGKMDS--------RGEHRQDRRE------------RPI--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q5PQK2-1", "uniprot_id": "Q5PQK2_RAT", "id": "Q5PQK2-1", "name": "RNA-binding protein FUS", "aln": "---TDYTQQATQSYGAYPTQPGQGYSQQSNQPYGQQSYSGYGQSADTS--GYGQSSYGSSYGQTQNTGYGTQSAPQGYG------STGGYG-SSQS--SQSS-YGQQSSYPGYGQQPAPSSTSGSYGGSSQSSSYGQPQ-------------SGGYG----QQSGYGG---QQQSYGQQQSSYNP--------PQGYGQQNQYNSSSGGGGGGGGG-NYGQDQSSMSGGGG-GGGYGNQDQSGGGGGGYGGGQQDRGGRGRGG--------GGGYNRSSGGYEPRGRGGGRGGRGGMGGSDRGGFNKFGGPRDQ--GSRHDSEQDNSDNNTIFVQGLGENVTIESVADYFKQIGIIKTNKKTGQPMINLYTDRETGKLKGEATVSFDDPPSAKAAIDWFDGKEFSGNPIKVSFATRRADFNRGGGNG--RGGRGRGGPMGRGGYGGGGSGGGGRGG------------FPSGGGGG----GG--QQRAGDWKCPNPTCENMNFSWRSECNQCKAPKPDGPGGGPGGSHMGGNYGDDRRG-RGGYDRGGYRGRGG------DRGGFRGGRGGGDRGGFGPGKMDS--------RGEHRQDRRE------------RPY--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P35637-1", "uniprot_id": "FUS_HUMAN", "id": "P35637-1", "name": "RNA-binding protein FUS", "aln": "MASNDYTQQATQSYGAYPTQPGQGYSQQSSQPYGQQSYSGYSQSTDTS--GYGQSSY-SSYGQSQNTGYGTQSTPQGYG------STGGYG-SSQS--SQSS-YGQQSSYPGYGQQPAPSSTSGSYGSSSQSSSYGQPQ-------------SGSYS----QQPSYGG---QQQSYGQQQS-YNP--------PQGYGQQNQYNSSSGGGGGGGGGGNYGQDQSSMSSGGGSGGGYGNQDQSGGGGSG-GYGQQDRGGRGRGGSGGGGGGGGGGYNRSSGGYEPRGRGGGRGGRGGMGGSDRGGFNKFGGPRDQ--GSRHDSEQDNSDNNTIFVQGLGENVTIESVADYFKQIGIIKTNKKTGQPMINLYTDRETGKLKGEATVSFDDPPSAKAAIDWFDGKEFSGNPIKVSFATRRADFNRGGGNG--RGGRGRGGPMGRGGYGGGGSGGGGRGG------------FPSGGGGG----GG--QQRAGDWKCPNPTCENMNFSWRNECNQCKAPKPDGPGGGPGGSHMGGNYGDDRRGGRGGYDRGGYRGRGG------DRGGFRGGRGGGDRGGFGPGKMDS--------RGEHRQDRRE------------RPY--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F1R0M4-1", "uniprot_id": "F1R0M4_DANRE", "id": "F1R0M4-1", "name": "RNA-binding protein FUS", "aln": "MASNDYGQTSSHGYGGYGGQSGQSYSQPSAQNYSQQSYGGYNQSSESSSAPYNQGGYSSNYGQSQSGGYGSQAPSQGYSQSSQSYSSGGYSNTSQPPPAQSGGYSQQSSYSGYNQ-SSPASAPGGYSSSSQSSGYGQQQQQSGGGYGGSGGQSGGYGSSGGQSSGFGGSGGQHQSSQSGGGSYSPSPNYSSPPPQSYGQQSQYGQGG-----------YNQDSPPMSGGGG-GGGYGGQDG--------GYSQDGRGGRGRGG---------GFGGRGAGGFDRGGRGGPRG-RGGMGMGDRGGFNKFGGPRDHGAGGPNMQEQDNSDNNTIFVQGLGDDYTVDSVADYFKQIGIIKVNKKTGLPMINLYTDRETGKLKGEATVSFDDPPSAKAAIDWFDGKDFNGNPIKVSFATRRAEFGRGGSSGGMRGGRGRGGPMGRGGFGGGRGGGGGGGG------------FQGNNGGGSGNGGG--QQRAGDWKCSNPSCGNLNFSWRNECNQCKEPKPEGSGG--GMSPMGGGFGG-ERG-RSGFDRGGFRGRGG------DRGGFRGGRGG-DRGGFGPGKMDS--------RGDHRHDRRD------------RPY--", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q27294-1", "uniprot_id": "CAZ_DROME", "id": "Q27294-1", "name": "RNA-binding protein cabeza", "aln": "-----------MERGGYGGGSGQGYNNFAVPPPN------YQQMPNKTG---NYNEPPPNYGK-QGGGYDSGSGHRGSG------GSGNGG-------------GGGGSWNDRGG-----NSYGNGGASKDSYNKGH----------------GGYS-----GGGGGG--------GGGGGGGSG----------GNDMITQED------------------------------------------------------------------------------------------------------------------------------TIFVSGMDPSTTEQDIETHFGAIGIIKKDKRTMKPKIWLYKNKETGASKGEATVTYDDTNAAQSAIEWFDGRDFNGNAIKVSLAQRQNNWNKGGGGG--GGGGGRGGFGGRRGGGGGGGGGGGGGGRFDRGGGGGGGRYDRGGGGGGGGGGGNVQPRDGDWKCN--SCNNTNFAWRNECNRCKTPKGDDEGS--SGGGGGGGYGGGGGG--GGYDRGNDRGSGGGGYHNRDRGGNSQGGGGGGGGGGGYSRFNDNNGGGRGGRGGGGGNRRDGGPMRNDGGMRSRPY--", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VGJ3-1", "uniprot_id": "Q9VGJ3_DROME", "id": "Q9VGJ3-1", "name": "", "aln": "--MDSTSASVVYTNSFYAPNYSDTQQPQPQLQTQQQMFHANYIVGTTLGSGLGFNFAPAPIPQASAASGLSPRGMYSDLYRYED-GSGDASGSLLLVQEDDHFCGAEADQQLVASTSSSCPMASSGESVSIDTEQEAERDLQMN--------QCETLEREELNGDIGEMGEMEELAEEVNGEQRP------PLLPCMGGNTSYMVFP--------------------------------------------------------------------------------------------RTAADYMPRLALPRHRPYISIGQEQYVIQAETVFVLGMRLNVTKNDIILFFGKVGVIKMDESTNKPKIFVYKNKITGRSKGEATITYVSPFSAQAAISCLSGAKFMGQVITVLPAYLSTRRGSVRYSYP----RELNAPEHQRRQR-----------------------------------AMKWKPAIDNWVCM--LCRNSNFVWRSSCNRCQADKVVAPQNNEGSSWAGSREEDGAPRRWRPYRNDWLCKICY-------NMNFWYRAKCNRCHALRSDEMKS--------SESTEEDTWELVLN--------PPIAE", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . * .: . . . . . . : . . : . .:*. . . .. .. . . . . * . . .. . : .:* * * * ** **..**:*: * . . . *. . : .. . . . ..:.. : : * ", "identical_positions": 17, "similar_positions": 57, "identity": "2.75%" }, { "cls_id": "homologset.agr.MGI:1353635", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9NZU5-1", "uniprot_id": "LMCD1_HUMAN", "id": "Q9NZU5-1", "name": "LIM and cysteine-rich domains protein 1", "aln": "--------------MAKVAKDLNPGVKKMSLGQL--QSARGVACLGCKGTCSGFEPHSWRKICKSCKCSQEDHCLTSDLED------------------------------------------------------------------------------------------------------------------------------------------------------DRKIGRLLMDSKYSTLTARVKGGD----------------------------------------------GIRIYKRNRMIMTNPIATGKDPTFDTITYEWAPPGVTQKLGLQYMELIPKE-------------------KQPVTGTEGAFYRRRQLMHQLPI-----------------YDQDPSRCRGLLENELKLMEEFVKQ---------------------------------------------------------------------------------------------------------------------------------------YKSEALGVGEVALPGQGGLPKEEGKQQEKPEGAETTAATTNGSLSDP-SKEVEYVCELCKGAAPPDSPVVYSDRAGYNKQWHPTCFVCAKCSEPLVDLIYFWKDGAPWCGRHYCESLR-PRCSGCDEIIFAED-YQRVEDLAWHRKHFVCEGCEQLLSGRAYIVTKGQ-----------LLCPTCSKSKRS-------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8VEE1-1", "uniprot_id": "LMCD1_MOUSE", "id": "Q8VEE1-1", "name": "LIM and cysteine-rich domains protein 1", "aln": "--------------MAKVAKDLNPGVQKMSLGQQ--QSARGVACLRCKGMCSGFEPHSWRKICKSCKCSQEEHCLSSDLDD------------------------------------------------------------------------------------------------------------------------------------------------------DRKIGRLLMDSKYATLTARVKGGD----------------------------------------------GIRIYKRNRMIMTNPIATGKDPTFDTITYEWAPPGVTQKLGLQYMELIPKE-------------------RQPVTGTEGALYRRRQLMHQLPI-----------------YDQDPSRCRGLVENELKAMEEFVKH---------------------------------------------------------------------------------------------------------------------------------------YKSEALGVGEVALPGQGGLPKEENKTQEKPEGTETTAPTTNGSLGDP-SKEVEYVCELCKGAAPVDSPVVYADRAGYSKQWHPTCFQCIKCSEPLVDLIYFWKDGAPWCGRHYCESVR-PRCSGCDEIIFSED-YQRVEDLAWHRKHFICEGCEQLLSGRAYIVTKGQ-----------LLCPTCSKSKRS-------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "E7FCK0-1", "uniprot_id": "E7FCK0_DANRE", "id": "E7FCK0-1", "name": "", "aln": "----------------------------MSKGPL--PAGKGAACLTCKGICPGFQPHSWRKACVKCQCSQDEHAFISNNED------------------------------------------------------------------------------------------------------------------------------------------------------DLKVGRLLADSRYTHLTAKVKGGD----------------------------------------------GTRVYKRNRMIVTNPVVSRKDPTFNTVTYDWAPTGLTQKLAMLYMSLLPEE-------------------RRPVAGTEGSLYRHKQLTRQLPA-----------------YDHDPAYCHSLSEAELKVMAQFVKS---------------------------------------------------------------------------------------------------------------------------------------YKEESLGVGEVALPGEKSTTKRNEKISQEQPDPPLTEQTPDGAIESPVSNETEYYCSGCGQLAAMDEPVVYADRAGYERLWHPACFVCGECGEALVDLIYFWKEGALLCGRHYCQSIR-PRCLGCDELIFSDMLLQEASGHVWHKEHFCCWLCGQDIR-----VECG-----------------CDKRQTT-------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A1ZAT5-1", "uniprot_id": "A1ZAT5_DROME", "id": "A1ZAT5-1", "name": "", "aln": "MSAVSPNSCVETPKAPEWLSKLESRREQLKRSKLGHEAGAGAPCAECKDKCPGLDLHFWRKVCRNCKCPKIQHVCPDDDDATGWAQFEILGQIRAKPAYIKIKALASQPVQLEWVPPNAAPDVVTDYMEKLGTAQIPVAGSDAALKRKMQLELQVPPHDLDAALCDGLTETEAIQLQQYVQKLREQCVGQGVVVRLGDRLNHAQVEHVAPALMPTQEAQQTWQSLGLMPVADDTLNELLANPKVAQALASPASAHPKLLVAFSEPLCESTAQFEENGALRAQTREKLLGISKPALLSLVTHGIVYDKVLGILQEKKLNISRDPKLGPIAEFRKEYVNNPQFRAEINTICPQPPMTPIKSPPGTPFNSPLPLKNPVQIRMGAQMRQDTPMRRVKFGGVSTIVYDCGLPANTDYDRDPVFAQILQAEPLKHAFQEARAGRAPSSVVISNIPAPVASLAELRGLNPATRAQLQSVGLDKNMLQSAVSNAPYYDRLFRSLHDKGISHDQCHLLQPMKQVHDWLLDDDQLLDEIDKVFADMANGCKDISYPKPSLGELPTSQSSDSGFHSKPPTPGYGSEDLTAGQGRFASIPGIEDMNMYPSCAGMPEQFQQLRLHGDEASGKNSTRTILCADCNQPIAMGEVAVKADRAGKEIAWHPGCFKCITCRELLADLVYFFHQGQVFCGRDLAIRLKIPRCRACDELIFTKE-YTAAEEATFHIKHFCCYQCDEPLAGQQYIADEKSNMPLCLLCYDRLFAVRCQRCKVAIGPADQGVAWGDVHWHASCFVCAGVQCSKPLIGGRFCVKENMPFCSPTCVRSLIN", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :. . :. *..* **. *.*:: * *** * .*:*.: :* .: : * .:..** :.: : * ... * * :: : : :**.:..:: . :: : *: :.** *: *: ::: **:** .: * ** : .: * .* * .*: :.. . . : . .* . .. * * . .. .* :**** . *** ** * * * *.**:**:::* ***. . :: *** .***:**:. .. .:* :** * * : : . *.: : : ", "identical_positions": 77, "similar_positions": 104, "identity": "9.42%" }, { "cls_id": "homologset.agr.MGI:1353636", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A8QI13-1", "uniprot_id": "A8QI13_DROME", "id": "A8QI13-1", "name": "Activator of basal transcription 1", "aln": "-----------------------MKEIKRKSKPKRKPTRMEVEEIET----SDKPQPEDGESANGEANPSDEGDEMELASFKAACSSSDPAKKI-----------------KKGIIYISNIPKHMTLTRLREILGEYGGIGRAFLRSQ-----------------SSKHHNILFAEGWVEFKSKHVAKQLVLLLNNKQISTRNNSPFYYSLWSMEYLPRFKWARLAELMNFVQVTNSQ---------------------NHLEFLKKKAKEAK----------------EVKKAMKVLADRLLELPLDSNI------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "A8QI32-1", "uniprot_id": "A8QI32_DROME", "id": "A8QI32-1", "name": "Activator of basal transcription 1", "aln": "-----------------------MKEIKRKSKPKRKPTRMEVEEIET----SDKPQPEDGESANGEANPSDEGDEMELASFKAACSSSDPAKKI-----------------KKGIIYISNIPKHMTLTHLREILGEYGGIGRAFLRSQ-----------------SSKHHNILFAEGWVEFKSKHVAKQLVLLLNNKQISTRNNSPFYYSLWSMEYLPRFKWARLAELMNFVQVTNSQ---------------------NHLEFLKKKAKEAK----------------EVKKAMKVLADRLLELALDSNI------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VY84-1", "uniprot_id": "Q9VY84_DROME", "id": "Q9VY84-1", "name": "Activator of basal transcription 1", "aln": "-----------------------MKEIKKKSKPKRKPTRMEVEESEPEMPFSYKTQPDEGESVNGEAHTSDDGDEMELATFKAAS--------------------------KKGVIYISNLPKHMTLTRLREILGEYGAIGRAFLRSQKL---------------SRKPHNFLFAEGWVEFKSKRVAKQIVPLLNYKQISTHKKSPFYYSLWIMEYLPRFKWARLNELMNIVPVTNSQ---------------------NHLKFLNKKAKKAK----------------KVKKAKKALADRLLELVLASSI------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9W394-1", "uniprot_id": "Q9W394_DROME", "id": "Q9W394-1", "name": "Activator of basal transcription 1", "aln": "-----------------------MKNIKNKSKPKRKPTPMEVEEAELDEVRSDEPQPGEGETANGEANPSDDDDDMDLANFKATSSSSAPAKKR-----------------KMGIIYISNIPKHMNVTRLREILGEYGAIGRVYLQPEKLSSAKAK-------KNKRKRYNIHFTEGWVEFKSKRVAKQIVPLLNNKQISGRKTSQFYDSLWSMKYLPRFKWVHLTERMNYEQAVHKQRLHTEVSQ-----------ARKETTFFQNNLDKSE----------------FIRKQAKKAKNAEKALAAKSDSDA----------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9W393-1", "uniprot_id": "Q9W393_DROME", "id": "Q9W393-1", "name": "Activator of basal transcription 1", "aln": "---------------------------------------MKVEETKLDEARWGKPQTKEGESANGIANPSND-DKKELANFKATFNSWAPEKKREKM-------------HKVGVILISNIPKDMDGDCLKEIMNLHSVVGRVYVQPETL---------------SSFKTKKNMRKGWVEFISKSGAKKIALELNNKPITDGKSSRFRGLLWKMKFLPRFKWYYLTDRMDYELAVCKVRVWSQARKRA-----TFWYDPDQMEYFKKQVKKMKKMK-------------KVKEAEMATRNAEMAAKKAEMAAKKLKKSA----------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q8IRM9-1", "uniprot_id": "Q8IRM9_DROME", "id": "Q8IRM9-1", "name": "Activator of basal transcription 1", "aln": "---------------------------------------MKVEETKLGEVRSGKPQTKEGESANGVANPSND-DKKELANFKATFNSWAPEKKREKM-------------HKVGVILISNIPKDMDGDCLKEIMNLHSVVGRVYVQPETL---------------SSFKTKKNMRKGWVEFISKSGAKKIALELNNKPITDGKSSRFRGLLWKMKFLPRFKWYYLTDRMDYELAVCKVRVWSQARKRA-----TFLYDPDQMEYFKKQVKKMK----------------KVKKAEMATRNAEMAAKKAEMAAKKLKKSA----------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q4KLM5-1", "uniprot_id": "ABT1_RAT", "id": "Q4KLM5-1", "name": "Activator of basal transcription 1", "aln": "-------------------------------------------MVKVGKLVEEQKAAMEEEKEV----NAEAAEELEEAEEASCNGS---KKKVVP-----------------GIVYLGHVPPRFRPLHVRNLLSVYGEVGRVFFQAEDPFVRRKKKAAAAAGGKKGAKYSKDYTEGWVEFRDKRIAKRVAASLHNTPMGARKRSPFRYDLWNLKYLHRFTWSHLSEHLAFERQVRRQRLRAEVAQAKRETDFYLRNVEQGQRFLAADGDATRPNSSWTFTQRPTEQELRAQKGARPGGRERARLATVQDQARSNRGLLARIFGASLLAESRKEP------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9QYL7-1", "uniprot_id": "ABT1_MOUSE", "id": "Q9QYL7-1", "name": "Activator of basal transcription 1", "aln": "-------------------------------------------MVKAGELVEQQKAAMEEEA------NAEAAEDQEEPEDTACSSSSKKKKKVVP-----------------GIVYLGHVPPRFRPLHVRNLLSAYGEVGRVFFQAEDHFVKRKKKAAAAAGGKKGAKYSKDYTEGWVEFRDKRVAKRVAASLHNTPMGARKRSPFRYDLWNLKYLHRFTWSHLSEHLAFERQVRRQRLRAEVAQAKRETDFYLRNVEQGQHFLAADGDATRPNSSWTFTQRPTEQEFRARKAARPGGRERARLANVEDQARSNRGLLAKIFGAPLPAESKEKP------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9ULW3-1", "uniprot_id": "ABT1_HUMAN", "id": "Q9ULW3-1", "name": "Activator of basal transcription 1", "aln": "-----------------------------------------------MEAEESEKAATEQEPLEGTEQTLDAEEEQEESEEAACGSK----KRVVP-----------------GIVYLGHIPPRFRPLHVRNLLSAYGEVGRVFFQAEDRFVRRKKKAAAAAGGKK-RSYTKDYTEGWVEFRDKRIAKRVAASLHNTPMGARRRSPFRYDLWNLKYLHRFTWSHLSEHLAFERQVRRQRLRAEVAQAKRETDFYLQSVERGQRFLAADGDPARPDGSWTFAQRPTEQELRARKAARPGGRERARLATAQDKARSNKGLLARIFGAPPPSESMEGPSLVRDS", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P53743-1", "uniprot_id": "ESF2_YEAST", "id": "P53743-1", "name": "Pre-rRNA-processing protein ESF2", "aln": "MSEKVNSDFEDFSSDEETDQHNVLIQTKKKISSKDDIFSKKVEDIESENESDIEEEQKQEEKEDVEQPDKENGEKLDREVEEQASSTTSLDLKTEKLRQLVKSKAAKKSKHKTGVVYFSSIPPYMKPAKMRQILTRFGEVDRLFLKKEDDQKYKQR-------VKGGGNKKNKYEEGWAEFIRKRDAKLCAETLNGNIIGGKKGTFYHDDILNVKYLPGFKWADLTEQIARENDIRQAKLEMEISQANKLNAEFIRNVEQSKMIQNIKNSRKRAGKEGESADSHPHREFKQRRVETSRANAPSDIKQQSSGSKDLGNVLTNLL------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : * : :. : *:: :. :* : ::::: .. :.* :.: : . :**.** * ** . *: . : . : : : :::* *.* * : : . . . :. . ", "identical_positions": 16, "similar_positions": 48, "identity": "4.69%" }, { "cls_id": "homologset.agr.MGI:1353644", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "G3V7W0-1", "uniprot_id": "G3V7W0_RAT", "id": "G3V7W0-1", "name": "", "aln": "MSTAPSLSALRSSKHSGGGGGGS-------GSADPAWTSALSGNCSGHGPGSSPAGSTKPFVHAVPPSDPLRQANRLPIKVLKMLTARTGHILHPEYLQPLPSTPVSPIELDAKKSPLALLAQTCSQIGKPDPSPSSKLSSVASNGGGAGGAGSGAGGDKDAKSGPLKLSDIGVEDKSSFKPYSKPGSDKKEPGGGGGGGGGGGGGGG-VAAEKSGFRVPSATCQPFTPRTGSPSSSASACSPGGMLPSAGGGPEGKDDKKDPEAGGGGSSKGSGGAPADGVPAGLAHGRISCG-SGINVDVNQHSEGGPGGKALSSDCGGSSSSSSGSGPSAPTSSSVLGSGLVAPVSPYKPGQTVFPLPPAGMTYP-GSLAGAYAGYPPQFLPHGVALDPTKPGSLVGAQLAAAAAGSLGCSKPAGSSPLAGASPPS--VMTASLCRDPYCLSYHCASHLAGAAAASASCAHDPAAAAAALKSGYPLVYPTHPLHGVHSSLTAAAAAGATPPSLAGHPLYPYGFMLPNDPLPHICNWVSANGPCDKRFATSEELLSHLRTHTAFPGTDKLLSGYPSSSSLASAAAAAMACHMHIPTSGAPGSPGTLALRSPHHALGLSSRYHPYSKSPLPTPG--------------APVPVPAATGPYYSPYALYGQRLTTASALGYQ", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q7TMA2-1", "uniprot_id": "ZN503_MOUSE", "id": "Q7TMA2-1", "name": "Zinc finger protein 503", "aln": "MSTAPSLSALRSSKHSGGGGGGGGGGGSGGGSADPAWTSALSGNCSGHGPGSSPAGSTKPFVHAVPPSDPLRQANRLPIKVLKMLTARTGHILHPEYLQPLPSTPVSPIELDAKKSPLALLAQTCSQIGKPDPSPSSKLSSVASNGGGAGGAGNGAGGDKDAKSGPLKLSDIGVEDKSSFKPYSKPGSDKKEPGGGGGGGGGGGGGGG-VAAEKSGFRVPSATCQPFTPRTGSPSSSASACSPGGMLPSAGGGPEGKDDKKDPEAGGGGSSKGSGGASADGVPAGLGHGRISCG-GGINVDVNQHSEGGPGGKALGSDCGGSSSSSSGSGPSAPTSSSVLGSGLVAPVSPYKPGQTVFPLPPAGMTYP-GSLAGAYAGYPPQFLPHGVALDPTKPGSLVGAQLAAAAAGSLGCSKPAGSSPLAGASPPS--VMTASLCRDPYCLSYHCASHLAGAAAASASCAHDPAAAAAALKSGYPLVYPTHPLHGVHSSLTAAAAAGATPPSLAGHPLYPYGFMLPNDPLPHICNWVSANGPCDKRFATSEELLSHLRTHTAFPGTDKLLSGYPSSSSLASAAAAAMACHMHIPTSGAPGSPGTLALRSPHHALGLSSRYHPYSKSPLPTPG--------------APVPVPAATGPYYSPYALYGQRLTTASALGYQ", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q96F45-1", "uniprot_id": "ZN503_HUMAN", "id": "Q96F45-1", "name": "Zinc finger protein 503", "aln": "MSTAPSLSALRSSKHSGGGGGGGGG-----GGADPAWTSALSGNSSGPGPGSSPAGSTKPFVHAVPPSDPLRQANRLPIKVLKMLTARTGHILHPEYLQPLPSTPVSPIELDAKKSPLALLAQTCSQIGKPDPSPSSKLSSVASNGGGAGGAGGGAAGDKDTKSGPLKLSDIGVEDKSSFKPYSKPGSDKKEPGGGGGGGGGGGGGGGGVSSEKSGFRVPSATCQPFTPRTGSPSSSASACSPGGMLSSAGGAPEGKDDKKDTDVGGGG--KGTGGASAEGGPTGLAHGRISCG-GGINVDVNQHPDGGPGGKALGSDCGGSSGSSSGSGPSAPTSSSVLGSGLVAPVSPYKPGQTVFPLPPAGMTYP-GSLAGAYAGYPPQFLPHGVALDPTKPGSLVGAQLAAAAAGSLGCSKPAGSSPLAGASPPS--VMTASLCRDPYCLSYHCASHLAGAAAASASCAHDPAAAAAALKSGYPLVYPTHPLHGVHSSLTAAAAAGATPPSLAGHPLYPYGFMLPNDPLPHICNWVSANGPCDKRFATSEELLSHLRTHTAFPGTDKLLSGYPSSSSLASAAAAAMACHMHIPTSGAPGSPGTLALRSPHHALGLSSRYHPYSKSPLPTPG--------------APVPVPAATGPYYSPYALYGQRLTTASALGYQ", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6UFS5-1", "uniprot_id": "ZN503_DANRE", "id": "Q6UFS5-1", "name": "Zinc finger protein 503", "aln": "MITSP--SASRNS------------------DTDLVWESSSSSSRN-----NSSAVASKPFLHSVPPSDPLRQANRLPIKILKMLTARTGHILHPEYLQPLPSTPVSPIELDAKKSPLALLAQTCSQIGKPDPPPSSKLSSVTSNG----------SSEKESKSGPLKLSDIGVEDKSSFKPYSKP-ADKKDSSSGVSSG------------EKSGFRVPSATCQPFTPRTGSPNSSTSASP----MPSDGKGE--RDEKKDSDCNKNCSSDGSA-------PTSVSHSRISVSCAGINVEVNQHQETTSGSKAS-------ATSDSVSCVTSSSSASVLGSGLVAPVSPYKPGQTVFPLPPAGMTYP-GSLAGAYAGYPQHFLPHG--------GSLVNAQLAS----SLGCSK-AGSSPLAGASPPS--IMSASLCRDPYCLSYHCASHLAGAAGASCTHDSAAAAAASALKSGYPLMYPTHPLHGVHS----------SPPSFGGHPLYPYGFMLPNDPLPHVCNWVSANGPCDKRFSSSEELLNHLRTHTAFTGTEKLISGYPSSSSLASAAAAAMACHMHMPPSGAPGSPGTLALRSPHHALGLSSRYHPYSKSPLPTPG--------------APVPVPAATGPYYSPYALYGQRLTTASALGYQ", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q24423-1", "uniprot_id": "NOC_DROME", "id": "Q24423-1", "name": "Zinc finger protein Noc", "aln": "--------------------------------------------------------------------------MVVLEGGGGVVTIGNNQYLQPDYLAPLPTT------MDAKKSPLALLAQTCSQIG-ADSSAVKPLLAMDKNKTKPGACSSSSNSSSSSGSAEISAAKSPSGQAKSPKSSTPISSTATSASLSNTSTG----------EIKLAFKPYETNVLSHQNQNSFKSSSS--------LDAEPTRPSSKNSSSAQERVPSRSKSNAT-------PTDGGKAEISAHDSSSSRKTVSPSGSSQRGASPIVRSGMEVLNNANGTAQHPKEMSSMAAAAAAAAAAYKAAGPYGLNPLSALCCPPGMEQHANPAFRPPFAGGFSHHHAAMLAVAANGGYPGGAPGGGPAGQPNPYISYQRIKTPAGGEAIVPVCKDPYCQGCPYSAHTQQMLMGAPCPAGCTQCEHQKYGLAMASAAGLPPAH-----------------PYSQAAAAAAANAAAARSAPYVCSWVVGDAYCGKRFQTSDELFSHLRTHTGN-----LSDPAAAAAALAQSQAQSLLGTLFPPSALRAGYP--TPPLSPMSAAAAAARYHPYAKPPPGALAGGPSPFGAAGAFNPAAAAAAAALGPYYSPYAMYGQRMGAAHQ----", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : ::* ..: *:*:** ***:* :****************** .*... . * :: .* ....: *. :. :. : .* *. : : .... . . * .*: .:. .. :.. .**: : : ::... : . ..: *:. .:..** .. . .. . . : ..: . ... * :.:. .*..:.**.. . * :.: * * * ..: * . ... .. . ..: . ..*: ..:*:**** . ::* .: . . . . * * . . . . . . . *::*.** .:. *.*** :*:**:.******. * . .::::**.: * :: :. *.: .* * . ** * . ::*****:*.* : . *.....** ********:****: :* ", "identical_positions": 108, "similar_positions": 179, "identity": "16.1%" }, { "cls_id": "homologset.agr.MGI:1353645", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9QYZ9-1", "uniprot_id": "PRS30_MOUSE", "id": "Q9QYZ9-1", "name": "Serine protease 30", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MESRARCIFLLLLQILTRARGDILPSVCGHSRDAGKIVGGQDALEGQWPWQVSLWIT-----EDGHICGGSLIHEVWVLTAAHCFRRSLNPSFYHVKVG--------GLTLSLLEPHSTLVA--VRNIFVHPTYLWAD--ASSGDIALVQLDTPLRPSQ-FTPVCLP-AAQTPLTPGTVCWVTGWGATQE----RDMASVLQELAVPLLDSEDCEKMYHTQGSSLSGERIIQSDMLCAGYVEGQKDSCQGDSGGPLVCSI-NSSWTQVGITSWGIGCARPYRPGVYTRVPTYVDWIQRILAENHSDAYGYHSSASAAYQMLLPVLLAVALPGSL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P83748-1", "uniprot_id": "PRS30_RAT", "id": "P83748-1", "name": "Serine protease 30", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MESWARCIFLLLLQILTGGRGDIL-----HS-GAGKIVGGQDAPEGRWPWQVSLRTE-----KEGHICGGSLIHEVWVLTAAHCFRRPLNSSFYHVKVG--------GLTLSLTEPHSTLVA--VRNIFVYPTYLWED--ASSGDIALLRLDTPLQPSQ-FSPVCLP-QAQAPLTPGTVCWVTGWGATHE----RELASVLQELAVPLLDSEDCERMYHIGETSLSGKRVIQSDMLCAGFVEGQKDSCQGDSGGPLVCAI-NSSWIQVGITSWGIGCARPNKPGVYTRVPDYVDWIQRTLAENHSDAYGCRSRASGAYPALLLVLLAFALPESL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0A8M1Q1Z2-1", "uniprot_id": "A0A8M1Q1Z2_DANRE", "id": "A0A8M1Q1Z2-1", "name": "", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MTDSCLQLFLMATGLST-----CLAQVCGRPPLGKRIVGGVEASPGSWPWQVDIQMG-----SNGHVCGGSIIAKNWVLSAAHCFPNPSEVSAYTLYMG--------RHLLNGYNQFEKVSY--VQRVVIPEGYTDPQ--GGR-DVALVQLRAPVSWTDRIQPVCLP-FADFQFNSGTLCYVTGWGHKQEGVS-LTGAAALREVEVPIIDQSSCQFMYQILSSDSS-TVDILSDMICAGYKEGGKDSCQGDSGGPLVCPVGNGTWIQAGVVSFGLGCAQKNRPGIYSRVSSFEKLIRTTVPEAYFLGHACRSESQTPLVTVLSLALVLIWR---", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q05319-1", "uniprot_id": "STUB_DROME", "id": "Q05319-1", "name": "Serine proteinase stubble", "aln": "--------------------------------MKQPTLIRPRLRHRRSTPAAATKMCPKRHWLVNNRAAGSRGSGGAAARSRRSLDQIVEVLVALIVVNCLATAAAALITPPDSLESLGSLGIPSSSASSSEDDDDMSSG----------FYRIPHRLEGYPQLQQLQRGQNFKISPKPCSFGRVEGTCMFVWECIKSEGKHVGMCVDSFMFGSCCTHNYTDNIVLPQTAFSYTRPTKPLTLRPRPPAAPYKPMISGMTTIERPHGAGTLVIRPSGPHHQGTLARPHPPPYQSKPTTASDLHGSASHPSSSSSSSSSSNPNSIWHTSTQQQQQQQHQQNQQNHWQMTTEPSFITKPRPTGWTKPGIVNLPMPARPSKPSKPTKKPIVYDRTPPPPPSVPPSTSTSTTSTSLIWPAQTHPPQPHRPTRPQLSPGTSLAASSSSHWPSSTTSTTSSTTSTTTTTTTTRRTTTPTTTTRRTTTNKPTRPYQRPTTATSSSSTSTTSSKTPTTTRPISSSSSSSSGIVTSSQRPTQP---------------------------THRTPVLATSGIETNEISDSSIPDAGALGHVKTISAARSECGVPTLARPETRIVGGKSAAFGRWPWQVSVRRTSFFGFSSTHRCGGALINENWIATAGHCVDD-LLISQIRIRVG--------EYDFSHVQEQLPYIERGVAKKVVHPKYSFLT--YEY-DLALVKLEQPLEFAPHVSPICLP-ETDSLLIG-MNATVTGWGRLSEG---GTLPSVLQEVSVPIVSNDNCKSMFMRAG----RQEFIPDIFLCAGYETGGQDSCQGDSGGPLQAKSQDGRFFLAGIISWGIGCAEANLPGVCTRISKFTPWILEHVR---------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "M9NDV6-1", "uniprot_id": "M9NDV6_DROME", "id": "M9NDV6-1", "name": "Peptidase S1 domain-containing protein", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MLKIVFVVAVLSLVKCAQSQIAFSNQPCSVRNPKIVGGSEAERNEMPYMVSLMRR------GGHFCGGTIISERWILTAGHCICNGLQQFMKPAQIQGVVGLHSIREYLNGIGNGPDALRVDFKNIVPHPQYDCND--VKH-DIALLELVQPIRFSSHIQPSCVGSEEGHRSLEQEYGTVSGWGWTHENQAENDRSDVLRKATVKIWNNEACERSYRSLG----KSNTIGETQLCAGYENGQIDSCWADSGGPLMSKE----HHLVGVVSTGIGCARPGLPGIYTRVSKYVSWMQKVIDGRK------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "A1Z7M5-1", "uniprot_id": "A1Z7M5_DROME", "id": "A1Z7M5-1", "name": "Peptidase S1 domain-containing protein", "aln": "-------------------------------MQLLLWLCLCLLLLICQSSPSQANILN--------------------------------------------------------------------------------------------------TLLGVPAECVHQSGVWPCKLSFSCWLQGGK-------------------------------------HAKGCGSNK----------------------------------------WLFSCCVAETQHPHQQQHHSPSSPLAN-------------------------------------------------------------------LVDYGKLKLNLNSLPKRIMLR------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------RRDDNELLNPKPECGVPRTAQNTLQKRIIGGRPAQFAEYPWQAHIRIA-------EYQCGGVLISANMVATAAHCIQQ-AHLADITVYLG-----ELDTQDLGHIHEPLPVEKHGVLQKIIHPRFNFRMTQPDRYDIALLKLAQPTSFTEHILPICLP--QYPIRLIGRKGLIAGWGKTEAHMG-HAGTNMLQVASVPIITTLDCIRWHESKQ----INVEIKAEMFCAGHSDGHMDACLGDSGGPLVIKE-RGRFVLVGITSAGFGCGVDHQPGIYHNVQKTVRWIQEVVARNEP-----------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "A1Z7M7-1", "uniprot_id": "A1Z7M7_DROME", "id": "A1Z7M7-1", "name": "Peptidase S1 domain-containing protein", "aln": "MLVATDENNTNTTTASRSTRNTWRWSRLALAVSLFAYCCCASSAATPTTSVTTAALLSGHQLLPWQTAAATAATTPSTARNLYAPHQSFSRHDDISFKDLRQRSDGTVVQSFGSYRTARQFGGYSTTAQRRSDPAVEIIPAPSVELPQGELITVPKQLVPTMPENVTRQGRRRNYMYIPLQTEGENGSAALLQLRPSRNATLSALGPPADGVAAVAHEFGADLATQGSGPEQPPLALELGPERTERSDLMAAASSTDKLEYAEPENTSRRVGFQFPSYSLKPASPFHPQAYREDNPIFGDTSAGGYEPQPYSEDASPVPPPTQYEQHETRHTRQLYFDSDTASSSFEFPGLVSNSKPHGLKLYRDDVTKFGDINGPITALPQQRPQRGFYFGDTEFRTGPPAPVRQFGPQKNFQEYVGPSEYQGTRKSRYYPYKSSRSPRVVFPTNDNVGTTGPSGPAGSSGPSGNGVYFSDNIAFRDQNFGINELAAVQDVRNDYSLQDLDSASEATSSPQSASTFKEKVDITTDTECQHRGGTCEFFLGCWLSGGLIQGTCDGLLRGCCHRTAKSANLGSSDFVGNAVDLTDLPQKNYGPVNNEPSCGIS-LAKQTAQRRIVGGDDAGFGSFPWQAYIRIG-------SSRCGGSLISRRHVVTAGHCVAR-ATPRQVHVTLG-----DYVIN---SAVEPLPAYTFGVRRIDVHPYFKFTP-QADRFDISVLTLERTVHFMPHIAPICLP--EKNEDFLGKFGWAAGWGALNPGS--RLRPKTLQAVDVPVIENRICERWHRQNG----INVVIYQEMLCAGYRNGGKDSCQGDSGGPLMHDK-NGRWYLIGVVSAGYSCASRGQPGIYHSVSKTVDWVSYVVGLTMNI----------------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :*:** * *: . : *** :* : :*.**. : . . : *:::: * . . * *: :*** . *: * : * . * :***. * *:* .****** *: * * .*. **: : : : ", "identical_positions": 41, "similar_positions": 37, "identity": "4.51%" }, { "cls_id": "homologset.agr.MGI:1353651", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8CI11-1", "uniprot_id": "GNL3_MOUSE", "id": "Q8CI11-1", "name": "Guanine nucleotide-binding protein-like 3", "aln": "MKRPKLKKASKRMTCHKRYKIQKKVREHHRKLRKEAKKRGHK--KPRKDPGVPNSAPFKEALLREAELRKQQLEELKQQQKLDRQKEQERKRKLEVSPGDEQSNVETREESD--EPKRKKAKAGK-----------------------------------QNPKKLHCQELKKVIEASDIVLEVLDARDPLGCRCPQIEEAVIQS-GSKKLILVLNKSDLVPKENLENWLNYLNKELPTVVFKASTNLK-NRK-TFKIKKKK-VVPFQS--KICCGKEALWKLLGDFQQS--CGKDIQVGVIGFPNVGKSSVINSLKQEW-----ICNVGISMGLTRSMQIVPLDKQITIIDSPCLIISPCNSPTALALRSPASIEELR-PLEAASAILSQADNEQVVLKYTVPEYKDSLHFFTKLAQRRGLHQKGGSPNVESAAKLVWSEWTGASLGYYCHPPASWNHSLHFNENIAAVMKKGFNLEELEKNNAHSIQVLKGPHLTNRILFRSSGLTNGILDE----KDIVEESPRQTEDKQD------ADDQENGSGERNAEISDVAPVEETRELSPEQSTAGKPSDGSSALDRASQEDETYDFTTDYI", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q811S9-1", "uniprot_id": "GNL3_RAT", "id": "Q811S9-1", "name": "Guanine nucleotide-binding protein-like 3", "aln": "MKRPKLKKASKRMTCHKRYKIQKKVREHHRKLRKEAKKRGHK--KPKKDPGVPNSAPFKEALLREAELRKQQLEELKQQQKLDRQKEQERKRKLEISPDDEQSNVETQEESD--EPKIKKAKSGK-----------------------------------QNPKKLHCQELKKVIEASDIVLEVLDARDPLGCRCPQVEEAVIQS-GCKKLVLVLNKSDLVPKENLENWLTYLNKELPTVVFKASTNLK-NRKKTFKIKKK--VVPFQS--KLCCGKEALWKLLGGFQQS--CGKGVQVGVVGFPNVGKSSIINSLKQER-----ICSVGVSMGLTRSMQIVPLDKQITIIDSPCFIISPCNSPAALALRSPASIEVLR-PLEAASAILSQADSQQVVLKYTVPGYKDSLDFFTKLAQRRGLHQKGGSPNVESAAKLLWSEWTGASLGYYCHPPASWNHSPHFNENITAIMKRGFNLEELEKNNAHSIQVLKGPHLTNKILFRSSGLTNGILEE----KDIPEESPKQTEDQQD------GDDQEHVTGEKNAEISDVTPVEETREMSPGQSTASKPSDRSFILDKMSEEDDAYDFTTDYI", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9BVP2-1", "uniprot_id": "GNL3_HUMAN", "id": "Q9BVP2-1", "name": "Guanine nucleotide-binding protein-like 3", "aln": "MKRPKLKKASKRMTCHKRYKIQKKVREHHRKLRKEAKKRGHK--KPRKDPGVPNSAPFKEALLREAELRKQRLEELKQQQKLDRQKELEKKRKLETNPDIKPSNVEPMEKEFGLCKTENKAKSGK-----------------------------------QNSKKLYCQELKKVIEASDVVLEVLDARDPLGCRCPQVEEAIVQS-GQKKLVLILNKSDLVPKENLESWLNYLKKELPTVVFRASTKPKDKGKITKRVKAKKNAAPFRS--EVCFGKEGLWKLLGGFQET--CSKAIRVGVIGFPNVGKSSIINSLKQEQ-----MCNVGVSMGLTRSMQVVPLDKQITIIDSPSFIVSPLNSSSALALRSPASIEVVK-PMEAASAILSQADARQVVLKYTVPGYRNSLEFFTVLAQRRGMHQKGGIPNVEGAAKLLWSEWTGASLAYYCHPPTSWTPPPYFNESIVVDMKSGFNLEELEKNNAQSIRAIKGPHLANSILFQSSGLTNGIIEE----KDIHEELPKRKERKQEEREDDKDSDQETVDEEVDENSSGMFAAEETGEALSEETTAGEQSTRSFILDKIIEEDDAYDFSTDYV", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6DRP2-1", "uniprot_id": "GNL3_DANRE", "id": "Q6DRP2-1", "name": "Guanine nucleotide-binding protein-like 3", "aln": "MKRPKLKKASKRLSCAKRYKIQKKVREHNRKLKKAAKKQGISR-KAKKDIGVPNSAPFKEEVLREAEQRKQELETLKEQNKIVKQQEKAAKRKKEK--DAASSVKEPAAKKAKKAAKIKEARAAIV--------------------------------KVKSAKTFKCQELNKVIEASDVIVEVLDARDPLGCRCPQLEEMVLKHEGKKKLLFILNKIDLVPKDNLEKWLHFLEAECPTFLFKSSMQLKDRTVQQKRQQRGTNAVLDHSRAASCFGKDFLLQTLNDLANKKEGETMLKVGVVGFPNVGKSSIINSLKEMR-----ACNAGVQRGLTRCMQEVHITKKVKMIDSPGILAALSNPGSAMALRSLQVEEKEESPQEAVRNLLKQCNQQHVMLQYNVPDYRSSLEFLTTFAMKHGLLQKGGVADTELAATTFLNDWTGAKLSYYSRVPERQGLPSYLSDAIVTELQSDVDMDAVKKGNENVKRSVRFPNLASCISFDSSGPTAGVLDVSELPKEILTKAATTTDAEEEKMDTTTNTDEPEAESHISSTVEPIQEPTEKRKDKPAKEVKFVPVNTDLTSMQNKNNEDAYDFNTDFV", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P40010-1", "uniprot_id": "NUG1_YEAST", "id": "P40010-1", "name": "Nuclear GTP-binding protein NUG1", "aln": "--MRVRKRQSRRTSTKLKEGIKKKASAHRKKEKKMAKKDVTWRSRSKKDPGIPSNFPYKAKILEEIEAKKMKDLEERELAKQQRLEARKAAKEQGVDAMDEDMIEDDENGLAALVESAQQAAAEYEGTPSNDADVRDDELDVIDYNIDFYGEDVEGESELEKSRKAYDKIFKSVIDASDVILYVLDARDPESTRSRKVEEAVLQS-QGKRLILILNKVDLIPPHVLEQWLNYLKSSFPTIPLRASSGAVNGTSFNRKLSQTT-------------TASALLESLKTYSNNSNLKRSIVVGVIGYPNVGKSSVINALLARRGGQSKACPVGNEAGVTTSLREIKIDNKLKILDSPGICFPSENK------------KRSKVEHEAELALLNALP-----AKHIVDPYPAVLMLVKRLAKS--------------------DEMTESFKKLYEIPPIPANDADTFTKHFLIHVAR-----KRGRLGKGGIPNLASAGLSVLNDWRDGKILGWVLPN--------TSAAASQQDKQN---------LSTINTGTKQAPIAANESTIVSEWSKEFDLDGLFSSLDKAIDASKDQDTMME------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *: *:* : : *:**. *.:* :* *** :.:** *:*.. *:* :*.* * :* . :: * : : :: : . ::* : :..:. : ::.**:***::: ******* . *. ::** ::: *:*:::*** **:* . **.** :*: . **. :::* : . . * : * :. : ***:*:*******:**:* * .* . *:* .:: : : :::.::*** : . * : . ** :*. :: * * * :.. :* .: * : * * . :.. : : : . : . *: : .. :: . . : ::: . : . ::: : ", "identical_positions": 90, "similar_positions": 134, "identity": "14.98%" }, { "cls_id": "homologset.agr.MGI:1353652", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q5M936-1", "uniprot_id": "TOR3A_RAT", "id": "Q5M936-1", "name": "Torsin-3A", "aln": "MFFG---AFWLLLLLLLP-PLRPPGAQGHRGAKSPEQEADEP---IPWPSIQRLREQLRTAGTLSKRYWALFSCTLWPDHCE-DQETPVPPLGWSLPLWGRRSLDMLTSWFCRFQDCCSAG-NCRISNNFTGLESDLRVRLHGQHLASKLVLEAVKGYLEMP-QVGKALALSFHGWSGTGKNFVARMLVDNLYRDGMRSDCVKMFISTFHFPHPKYVDLYKEDLQRQMQETQRRCQQSTFVFDEAEKLHPGLLELLEPYLEPRSPETHGAELPRAIFLLLSNLGGSVINEVVLGLLKAGWSREEITLQHLEMPLQAEIIKSADSSFGSSRLLKKHLIDLFIPFLPLEYRHVRLCVRDAFL----GQDLPYTEEALDEIAKMMTYVPEEEQLFSSQGCKSISQRINLVLP", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9ER38-1", "uniprot_id": "TOR3A_MOUSE", "id": "Q9ER38-1", "name": "Torsin-3A", "aln": "MFLG---ALWLLLLL----PLRPPGAQG--------QEADEP---TPWPSVKGLKEQLRKAGALSKRYWELFSCTLWPDHCE-DQETPVPPLGWSLPLWGRRSLDVLTAWLCRFQDCCSGGGDCRISNNLTGLESDLRVRLHGQHLASKLVLRAVKGYLEMP-QVGKALALSFHGWSGTGKNFLARILMDNLYRDGMRSDCVKMFISTFHFPHPKYVDTYKEELQRQMQETQWRCHQSTFVFDEAEKLHPGLLELLEPYLEPRSPEARGVEAPRAIFLFLSNLGGSVINEVVLSLLKAGWSREEITTQHLEVPLQAEIMEAADSSFGSSGLLKKHLIDHFIPFLPLEYCHVRLCVRDAFL----GQDLPYTEETLDEIAKMMTYVPEEERLFSSQGCKSISQRINLFLP", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9H497-1", "uniprot_id": "TOR3A_HUMAN", "id": "Q9H497-1", "name": "Torsin-3A", "aln": "MLRGPWRQLWLFFLLLLPGAPEPRGASR------PWEGTDEPGSAWAWPGFQRLQEQLRAAGALSKRYWTLFSCQVWPDDCDEDEEAATGPLGWRLPLLGQRYLDLLTTWYCSFKDCCPRG-DCRISNNFTGLEWDLNVRLHGQHLVQQLVLRTVRGYLETP-QPEKALALSFHGWSGTGKNFVARMLVENLYRDGLMSDCVRMFIATFHFPHPKYVDLYKEQLMSQIRETQQLCHQTLFIFDEAEKLHPGLLEVLGPHLERRAPEGHRAESPWTIFLFLSNLRGDIINEVVLKLLKAGWSREEITMEHLEPHLQAEIVETIDNGFGHSRLVKENLIDYFIPFLPLEYRHVRLCARDAFL----SQELLYKEETLDEIAQMMVYVPKEEQLFSSQGCKSISQRINYFLS", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "O77277-1", "uniprot_id": "TORS_DROME", "id": "O77277-1", "name": "Torsin-like protein", "aln": "--------------------------------------------------------MMSFPRMLSLCLSVLVILPLPLQSVDPLTIGAVGAVALGAYFKEHT--------YCRFAECCDDR---NIPARIDELERSLERTLIGQHIVRQHIVPALKAHIASGNKSRKPLVISFHGQPGTGKNFVAEQIADAMYLKGSRSNYVTKYLGQADFPKESEVSNYRVKINNAVRDTLRSCPRSLFIFDEVDKMPSGVFDQLTSLVDYN-AFVDGTDNTKAIFIFLSNTAGSHIASHLGSVMKNGRLREDTRLSDFEPLLRKAAYN-MDGGMKKTTMIESHVIDHFIPFLPMEKAHVIKCLEAELLRWRRDPKQANNQKIIEDIINSSISYDRTHSLFAISGCKTLEKKVAMAIY", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . ** *. : : : .. .:. : : * * :** .*. .: ** .*. * ***:. : :: :::.:: : *.*.:**** .******:*. : : :* .* *: * ::. .**: . *. *: .: :::* * :: *:***.:*: .*::: * . :: . . .: . :**::*** *. * . : ::* * **: ..:* *: : *..: : :::.::** ******:* ** * . :* . . .:: :::* : . . **: .***::.::: : ", "identical_positions": 78, "similar_positions": 121, "identity": "19.07%" }, { "cls_id": "homologset.agr.MGI:1353653", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9JLZ1-1", "uniprot_id": "GLRX3_RAT", "id": "Q9JLZ1-1", "name": "Glutaredoxin-3", "aln": "MAAGAAEAAEAAVAVVEVGSARQFEELLRL-KTKSLLVVHFWAPWAPQCVQMNDVMAELAKEH--PHVSFVKLEAEAVPEVSEKYEISSVPTFLFFKNSQKVDRLDGAHAPELTKKVQRHVSSGSFPPSTNEHVKEDLNLRLKKLTHAAPCMLFMKGTPQEPRCGFSKQMVEILHKHNIQFSSFDIFSDEEVRQGLKTYSNWPTYPQLYVSGELIGGLDIIKELEASEELDTICPKAPKLEERLKVLTNKASVMLFMKGNKQEAKCGFSKQILEILNSTGVEYETFDILEDEEVRQGLKTFSNWPTYPQLYVRGDLVGGLDIVKELKDNGE--LLPILKGEN", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9CQM9-1", "uniprot_id": "GLRX3_MOUSE", "id": "Q9CQM9-1", "name": "Glutaredoxin-3", "aln": "MAAGAAEAGEAAVAVVEVGSAQQFEELLRL-KTKSLLVVHFWAPWAPQCVQMNDVMAELAKEH--PHVSFVKLEAEAVPEVSEKYEISSVPTFLFFKNSQKVDRLDGAHAPELTKKVQRHVSSGAFPPSTNEHLKEDLSLRLKKLTHAAPCMLFMKGTPQEPRCGFSKQMVEILHKHNIQFSSFDIFSDEEVRQGLKTYSNWPTYPQLYVSGELIGGLDIIKELEASEELDTICPKAPKLEERLKVLTNKASVMLFMKGNKQEAKCGFSKQILEILNSTGVEYETFDILEDEEVRQGLKTFSNWPTYPQLYVRGDLVGGLDIVKELKDNGE--LLPILKGEN", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O76003-1", "uniprot_id": "GLRX3_HUMAN", "id": "O76003-1", "name": "Glutaredoxin-3", "aln": "MAAGAAEA--AVAAVEEVGSAGQFEELLRL-KAKSLLVVHFWAPWAPQCAQMNEVMAELAKEL--PQVSFVKLEAEGVPEVSEKYEISSVPTFLFFKNSQKIDRLDGAHAPELTKKVQRHASSGSFLPSANEHLKEDLNLRLKKLTHAAPCMLFMKGTPQEPRCGFSKQMVEILHKHNIQFSSFDIFSDEEVRQGLKAYSSWPTYPQLYVSGELIGGLDIIKELEASEELDTICPKAPKLEERLKVLTNKASVMLFMKGNKQEAKCGFSKQILEILNSTGVEYETFDILEDEEVRQGLKAYSNWPTYPQLYVKGELVGGLDIVKELKENGE--LLPILRGEN", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q5XJ54-1", "uniprot_id": "GLRX3_DANRE", "id": "Q5XJ54-1", "name": "Glutaredoxin 3", "aln": "MAN-----------FTDAASLQQFDELLKN-NSKSLTVVHFHAPWAPQCSQMNDVMAELAKEH--KHTMFVKLEAEAVPEVSEKYEITSVPTFLFFKGGEKIDRLDGAHAPELTNKVQRLGSGGGGAVGAGDVPKEDLNQRLKRLINAAPCMLFMKGSPQEPRCGFSRQIIQILKDHNVQYSSFDILSDEEVRQGLKTYSNWPTYPQVYVSGELIGGLDIVKELVESGELENTFPKTVSLENRLKSLINKSPVMLFMKGNKEAAKCGFSRQILEIMNNTGVEYDTFDILEDEEVRQGLKTYSNWPTFPQLYVKGDLIGGLDIVKELLEGGE--LVSVLKGEN", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VJZ6-1", "uniprot_id": "Q9VJZ6_DROME", "id": "Q9VJZ6-1", "name": "", "aln": "------------MPVVNVSAAEEYQKYIN---ADKTTVALFAAEWAEQCGQVKDALEELAKITG-EKLQFISLNAEQFPEISMKHQIEAVPTVIFFAKGSAVDRVDGVDIAAISAKSKKLAENASSAAATGQT----------------------------------------------------------------------------------------------------------LEERLKALINTAPLMIFMKGDRNGPRCGFSKQLIGIVNETNLPYETFDILGDEEVRQGLKTYSDWPTYPQVYVKGELIGGLDIIKELLANNE--LESTLKG--", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P32642-1", "uniprot_id": "GLRX4_YEAST", "id": "P32642-1", "name": "Monothiol glutaredoxin-4", "aln": "------------MTVVEIKSQDQFTQLTTTNAANKLIVLYFKAQWADPCKTMSQVLEAVSEKVRQEDVRFLSIDADEHPEISDLFEIAAVPYFVFIQNGTIVKEISAADPKEFVKSLEILSNASASLANNAKGPKSTSDE------------------------------------------------------------------------------ESSGSSDD-----EEDETEEEINARLVKLVQAAPVMLFMKGSPSEPKCGFSRQLVGILREHQIRFGFFDILRDENVRQSLKKFSDWPTFPQLYINGEFQGGLDIIKESIEEDPEYFQHALQ---", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "Q03835-1", "uniprot_id": "GLRX3_YEAST", "id": "Q03835-1", "name": "Monothiol glutaredoxin-3", "aln": "------------MPVIEINDQEQFTYLTTTAAGDKLIVLYFHTSWAEPCKALKQVFEAISNEPSNSNVSFLSIDADENSEISELFEISAVPYFIIIHKGTILKELSGADPKEYVSLLEDCKNSVNSGSSQTHTMENANVN------------------------------------------------------------------------------EGSHNDEDDDDEEEEEETEEQINARLTKLVNAAPVMLFMKGSPSEPKCGFSRQLVGILREHQVRFGFFDILRDESVRQNLKKFSEWPTFPQLYINGEFQGGLDIIKESLEEDPDFLQHALQS--", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . : :: .. * * : ** * :.:.: ::: . *:.::*: .*:* .:* :** .::: . :..:.... : . . :: ** * : :.:*:****. . .:****:*:: *:.. : : **** **.***.** :*:***:**:*:.*:: *****:** . : *: ", "identical_positions": 53, "similar_positions": 75, "identity": "15.5%" }, { "cls_id": "homologset.agr.MGI:1353654", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P40336-1", "uniprot_id": "VP26A_MOUSE", "id": "P40336-1", "name": "Vacuolar protein sorting-associated protein 26A", "aln": "MSFLGGFFGPICEIDVALNDGETRKMAEMKTEDGK------VEKHYLFYDGESVSGKVNLAFKQPGKRLEHQGIRIEFVGQIELFNDKSN---------------------------THEFVNLVKELALPGELTQSRSYDFEFMQVEKPYESYIGANVRLRYFLKVTIVRRLTDLVKEY---------------------------DLI------------------------VHQLATYPDVNN---SIKMEVGIEDCLHIEFEYNKSKYHLKDVIVGKIYFLLVRIKIQHMELQLIKKEITGIGPSTTTETETIAKYEIMDGAPVKGESIPIRLFLAGYDPTPTMRDVNKKFSVRYFLNLVLVDEEDRRYFKQQEIILWRKAP------EKLRKQRTNFHQRFESP-------------DSQ--ASAEQPEM-------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6AY86-1", "uniprot_id": "VP26A_RAT", "id": "Q6AY86-1", "name": "Vacuolar protein sorting-associated protein 26A", "aln": "MSFLGGFFGPICEIDVALSDGETRKMAEMKTEDGK------VEKHYLFYDGESVSGKVNLAFKQPGKRLEHQGIRIEFVGQIELFNDKSN---------------------------THEFVNLVKELALPGELTQSRSYDFEFMQVEKPYESYIGANVRLRYFLKVTIVRRLTDLVKEY---------------------------DLI------------------------VHQLATYPEVNN---SIKMEVGIEDCLHIEFEYNKSKYHLKDVIVGKIYFLLVRIKIQHMELQLIKKEITGIGPSTTTETETIAKYEIMDGAPVKGESIPIRLFLAGYDPTPTMRDVNKKFSVRYFLNLVLVDEEDRRYFKQQEIILWRKAP------EKLRKQRTNFHQRFESP-------------ESQ--ASAEQPEM-------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O75436-1", "uniprot_id": "VP26A_HUMAN", "id": "O75436-1", "name": "Vacuolar protein sorting-associated protein 26A", "aln": "MSFLGGFFGPICEIDIVLNDGETRKMAEMKTEDGK------VEKHYLFYDGESVSGKVNLAFKQPGKRLEHQGIRIEFVGQIELFNDKSN---------------------------THEFVNLVKELALPGELTQSRSYDFEFMQVEKPYESYIGANVRLRYFLKVTIVRRLTDLVKEY---------------------------DLI------------------------VHQLATYPDVNN---SIKMEVGIEDCLHIEFEYNKSKYHLKDVIVGKIYFLLVRIKIQHMELQLIKKEITGIGPSTTTETETIAKYEIMDGAPVKGESIPIRLFLAGYDPTPTMRDVNKKFSVRYFLNLVLVDEEDRRYFKQQEIILWRKAP------EKLRKQRTNFHQRFESP-------------ESQ--ASAEQPEM-------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6TNP8-1", "uniprot_id": "VP26A_DANRE", "id": "Q6TNP8-1", "name": "Vacuolar protein sorting-associated protein 26A", "aln": "MSFLGGLFGPVCEIDVILNDAESRKTAELKTEEGK------LEKHYLFYDGESVSGKVNINVKQTSKRLEHQGIRIEFVGQIELFSDKSN---------------------------THEFVNLVKELALPGELTQNRSYDFEFMQVEKPYESYVGANVRLRYFLKVTIVRRLSDLVKEY---------------------------DLI------------------------VHQLATYPDVNN---SIKMEVGIEDCLHIEFEYNKSKYHLKDVIVGKIYFLLVRIKIQHMELQLIKKEMTGIGPSTTTETETVAKYEIMDGAPVKGESIPIRLFLAGYDLTPTMRDVNKKFSVRYFLNLVLVDEEDRRYFKQQEIVLWRKAP------EKMRKR--NFHQRYESP-------------EPRPSLSAEQPEM-------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9W552-1", "uniprot_id": "VPS26_DROME", "id": "Q9W552-1", "name": "Vacuolar protein sorting-associated protein 26", "aln": "MNFLG--FGQSADIEIVFDGAEH-KTAEVKGEDGK------VEKMLLFYDGETVSGKVNVTLKKPGSKLEHQGIKIEFIGQIELYYDRGN---------------------------HHEFKCLAKALARPGDLIQNNSYPFDFPKVEKQFEVYAGSNVRLRYFLRATIVRRISDITKEV---------------------------DIA------------------------VHTLCSYPEMNN---PIKMEVGIEDCLHIEFEYNKSKYHLRDTIIGKIYFLLVRIKIKHMEIAIIKKESTGTGPTMFNENETIAKYEIMDGAPVKGESIPIRVFLAGYNLTPTMRDINKKFSVKYFLNLVLMDTEDRRYFKQQEITLWRKADKPRYHGAQQHQQQQHQHVPLHAPPHLVSGPAAPTVAHSLISSSTDSGEVGGAPTAPGTAGSESKMGLFTRESPNQEFSQQQMDSPPLTPTPSTASVAVAVPTAASSVSEPAPERGIGDGAAAATTSASPVAMLSSSPPPLLPVSPLSRSETEASEQVQPEDEDLDAITPNTKKTGATPLATD", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P40335-1", "uniprot_id": "PEP8_YEAST", "id": "P40335-1", "name": "Carboxypeptidase Y-deficient protein 8", "aln": "---MSIFFKPPIDIEILFDNEESRKHVDIATRSSNSSYKSMKESLPVYEDGESLGGIVTLRVRD-SKKVDHLGIKVSVIGSIDMLKSHGSGNSSSKKVTSSTSSSSSNGSVDVRKNSVDQFLCQSYDLCPAGELQHSQSFPFLFRDLSKRYESYKGKNVDVAYYVKVTVMRKSTDISKIKRFWVYLYNSVTTAPNTLSANETKATTNDIAGGNYAADNASDNTQTKSTQGEAADVNQVLPISHSNNEPKPVRLDIGIENCLHIEFEYAKSQYSLKEVIVGRIYFLLTRLRIKHMELSLITRESSGLQTSNVMTDSTAIRYEIMDGSSVKGETIPIRLFLSGYDLTPNMS--CNYFNVKNYLSLVIIDEDGRRYFKQSEITLYRTR---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :. * :*:: :.. * * .:: ...: *. :: ***::.* *.: .:. ..:::* **::..:*.*:: .:.. .:* *. .*:* :..*: * * .:.* :* * * ** : *:::.*::*: :*: * *: *: : . .. ** .:::::***:******** **:* *::.*:*:*****.*::*:***: :*.:* :* .: .* :******:.****:****:**:**: **.* : *.*: :*.**::* :.******.** *:*. ", "identical_positions": 105, "similar_positions": 117, "identity": "18.49%" }, { "cls_id": "homologset.agr.MGI:1353655", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P57080-1", "uniprot_id": "UBP25_MOUSE", "id": "P57080-1", "name": "Ubiquitin carboxyl-terminal hydrolase 25", "aln": "MTVEQNVLQQSAAQKHQQTFLNQLREITG----INDAQILQQALKDSNG-----------------------------NLELAVAFLTAKNAKTPPQ---------EETGYYQT--------ALPGNDRYISVGSQADANVIDLTGDDKDDLQRAIALSLAESNRAFRETGITDEEQAISRVLEASIAENKACLKRTP-IEVWRDSRNPYDRKRQEKAPVGLKNVGNTCWFSAVIQSLFNLLEFRRLVLNYKPPSNAQDLPRNQKEHRNLPFMRELRYLFALLVGTKRKYVD-----PSRAVEILKDAFKSNDSQQQDVSEFTHKLLDWLEDAFQMKAEEETDEEKPKNPMVELFYGRFLAMGVLEGKKFENTEMFGQYPLQVNGFKDLHECLEAAMIEGEIESLHS-DNSGKSGQEHWFTELPPVLTFELSRFEFNQALGRPEKIHNKLEFPQVLYLDRYMHRNRE-ITRIKREEIKRLKDYLTVLQQRLERYLSYGSGPKR-----------FPLVDVLQYALEFASSKPVCTSPVDDIDASSSASGPLPSQSLPSTT-EQQGPCASDLPGSSSPASGAALPLRSVIHKPFTQSRIPPDLPMHPAPRHITEEELCVLESCLHRWRTEIENDTRDLQESISRIHRTIELMYSDKSMIQVPYRLHAVLVHEGQANAGHYWAYIFDHRESRWMKYNDIAVTKSSWEELVRDSFG--------------------------------GYRNASAYCLMYIDDKAQFLIQEEFNKETG----------QALVGMETLPPDLR---DFVEEDNQRFEKELEEWDTQLAQRSLQEKLLAAPKLREAEAS-----------------ATTAQAGG-ADYLEQPSRSDLSKHWKEETLRVIAKASHDLEDKGPETVLQS------------------------------------------------------------------------------------------AIKLEYSRLVKLAQEDTPPETDYRLHHVLVYFIQNQAPKKIIEKTLLEQFGDRNLSFDERCHNIMKVAQAKLEMIKPEEVNLEEY-EEWHADYKKFRETTMYLITGLENFQ----------RESYIDSLLFLLCAYQNNKELLSK---GPYRGHDGELISHYRRECLLKLNEQAAELFESGEDGDVNNGLIIMNEFIVPFLPLLLVDDMEEKDILAVEDMRNRWCSYLGQEMEANLQEKLTDFLPKLLDCSTEIKGFHEPPKLPSYSAHELCERFARIMLSLS--RTPADGR---------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8I5ZPF8-1", "uniprot_id": "A0A8I5ZPF8_RAT", "id": "A0A8I5ZPF8-1", "name": "Ubiquitin carboxyl-terminal hydrolase 25", "aln": "MTVEQNVLQQSAAQKHQQTFLNQLREITG----INDAQILQQALKDSNG-----------------------------NLELAVAFLTAKNAKTPPQ---------EETAYYQTA-------ALPGSDRYISVGSQADANVIDLTGDDKDDLQRAIALSLAESNRTFRETGITDEEQAISRVLEASIAENKACLKRTP-IEVWRDSRNPYDRKRQDKAPVGLKNVGNTCWFSAVIQSLFNLLEFRRLVLNYKPPSNAQDLPRNQKEHRNLPFMRELRYLFALLVGTKRKYVD-----PSRAVEILKDAFKSNDSQQQDVSEFTHKLLDWLEDAFQMKAEEETDEEKPKNPMVELFYGRFLAMGVLEGKKFENTEMFGQYPLQVNGFKDLHECLEAAMIEGEIESLHS-DNSGKSGQEHWFTELPPVLTFELSRFEFNQALGRPEKIHNKLEFPQVLYLDRYMHRNRE-ITRIKREEIKRLKDYLTVLQQRLERYLSYGSGPKR-----------FPLVDVLQYALEFASSKPVCTSPVDDIDATSSTSGSTSSQSLPSTT-EQQGTPASDLP-SSSPASGAALSLRSVIHKPFTQSRIPPDLPMHPAPRHITEEELSVLESCLHRWRTEIENDTRDLQESISRIHRTIELMYSDKSMIQVPYRLHAVLVHEGQANAGHYWAYIFDHRESRWMKYNDIAVTKSSWEELVRDSFG--------------------------------GYRNASAYCLMYINDKAQFLIQEEFNKETG----------QALVGMETLPPDLR---DFVEEDNQRFEKELEDWDTQLAQRALQEKLLAAQKLREAESS-----------------APTAQAGG-PDYLEQPSRSDLSKHWKEETLRVIAKASHDHEDKGPETVLQSKP--------------------ENTTSQPPSKQQAVEVQIPHIGKFMIESKEGGYDDEIMMTPSMQGIIMAIGKSRSVYDRCGPEAGFFKAIKLEYSRLVKLAQEDTPPETDYRLHHVLVYFIQNQAPKKIIEKTLLEQFGDRNLSFDERCHNIMKVAQAKLEMIKPEEVNLEEY-EEWHADYKKFRETTMYLIIGLENFQ----------RESYIDSLLFLICAYQNNKELLSK---GPYRGHDGDLISHYRRECLLKLNEQAAELFESGEDREVSNGLIIMNEFIVPFLPLLLVDETEERDILAVEDMRNRWCSYLGQDMEPNLQEKLTDFLPKLLDCSTEIKGFHEPPKLPSYSAHELCERFARIMLSLS--RTPADGR---------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9UHP3-2", "uniprot_id": "UBP25_HUMAN", "id": "Q9UHP3-2", "name": "Ubiquitin carboxyl-terminal hydrolase 25", "aln": "MTVEQNVLQQSAAQKHQQTFLNQLREITG----INDTQILQQALKDSNG-----------------------------NLELAVAFLTAKNAKTPQQ---------EETTYYQT--------ALPGNDRYISVGSQADTNVIDLTGDDKDDLQRAIALSLAESNRAFRETGITDEEQAISRVLEASIAENKACLKRTP-TEVWRDSRNPYDRKRQDKAPVGLKNVGNTCWFSAVIQSLFNLLEFRRLVLNYKPPSNAQDLPRNQKEHRNLPFMRELRYLFALLVGTKRKYVD-----PSRAVEILKDAFKSNDSQQQDVSEFTHKLLDWLEDAFQMKAEEETDEEKPKNPMVELFYGRFLAVGVLEGKKFENTEMFGQYPLQVNGFKDLHECLEAAMIEGEIESLHS-ENSGKSGQEHWFTELPPVLTFELSRFEFNQALGRPEKIHNKLEFPQVLYLDRYMHRNRE-ITRIKREEIKRLKDYLTVLQQRLERYLSYGSGPKR-----------FPLVDVLQYALEFASSKPVCTSPVDDIDASSPPSGSIPSQTLPSTT-EQQGALSSELP-STSPSSVAAISSRSVIHKPFTQSRIPPDLPMHPAPRHITEEELSVLESCLHRWRTEIENDTRDLQESISRIHRTIELMYSDKSMIQVPYRLHAVLVHEGQANAGHYWAYIFDHRESRWMKYNDIAVTKSSWEELVRDSFG--------------------------------GYRNASAYCLMYINDKAQFLIQEEFNKETG----------QPLVGIETLPPDLR---DFVEEDNQRFEKELEEWDAQLAQKALQEKLLASQKLRESETS-----------------VTTAQAAGDPEYLEQPSRSDFSKHLKEETIQIITKASHEHEDKSPETVLQS------------------------------------------------------------------------------------------AIKLEYARLVKLAQEDTPPETDYRLHHVVVYFIQNQAPKKIIEKTLLEQFGDRNLSFDERCHNIMKVAQAKLEMIKPEEVNLEEY-EEWHQDYRKFRETTMYLIIGLENFQ----------RESYIDSLLFLICAYQNNKELLSK---GLYRGHDEELISHYRRECLLKLNEQAAELFESGEDREVNNGLIIMNEFIVPFLPLLLVDEMEEKDILAVEDMRNRWCSYLGQEMEPHLQEKLTDFLPKLLDCSMEIKSFHEPPKLPSYSTHELCERFARIMLSLS--RTPADGR---------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M3B6G9-1", "uniprot_id": "A0A8M3B6G9_DANRE", "id": "A0A8M3B6G9-1", "name": "Ubiquitin carboxyl-terminal hydrolase 25", "aln": "MTVEQNVLQQHS-QKHQQTLLNQLREVTG----TTDVQLLQQALQVSNG-----------------------------DLVEAVAFLTEKNAKVPQQ---------DEATYYQT--------AQITNDRYISVGSQADTNVIDLTGDDKDDLQRAIALSLEESNRAFRETGITDEEQAISRVLEASIAENKASLKRTH-TEVWSDSPNPHERKRMENCPVGLKNVGNTCWFSAVIQSLFNLLEFQRLVLHYSPPARMQDLPRNQKEHRNLPFMQELRHLFSLLVGSKRKYVD-----PSGAVEILKDAFKSSESQQQDVSEFTHKLLDWLEDAFQIKAEEDREGEKPKNPMVELFYGRFLAVGVLEGKKFENTEMFGQYPLQVNGFKDLHECLEAAMIEGEIESLHSAENSAKSGQEHWFTELPPVLTFELSRFEFNQALGRPEKIHNKLEFPSMLYMDRYMDRNRE-ITRIKREEIRRLKEHLTVLQQRLERYLSYGSGPKR-----------FPLADVLQYAMEFASSKPVCTSPVEDIDTTAPPGGTIAQLPPPASAGEQPDACVSAEGSGSGLQASQQQQQRVSIHKPFTQSRVPPDLPMHPAPRHITEEELRVLESCLHRWRSEVENDTRDLQASISRIHRTIELMYSDKSMMQVPYRLHAVLVHEGQANAGHYWAYIYDRHHQRWMKYNDIAVTKSSWEELVRDSFG--------------------------------GYRNASAYCLMYIDDKKPFLIQEEFDKETG----------QMLSGLDKLPPDLK---VFVEADNKLFEREMEEWDALQARKLQQEKLALAAAAAAAAAASVAVQPMSTEPCSPDNTAPSAAPQHDPEYMEQQSPSGDSKHLQEDTERAISKAAAEHDEKSPEALLNTSQSSHPDSKLTSDPCPPPDPEQDDPTCPPPGPQRVVEVAIPNVGTFVIQSKEGGYDDEAMMTPNMQGIIMAIGKSRSVYDKCGPEAAFFKAMKVEYTRLLRLAQEDTPPERDYRLQHVIVFFIHNEAPKKIVERTLLMQFADRNLGFDERCKSIMKVARAKLELIKPDEVNMEEY-EMWHQDYRIFRETSVFLLIGLELFM----------KKSFVEALMYLIYAYQYNKELLAK---GPYRGHDEELIAHYRRECLLKLNEYAAALFETGEEAKVNTGLSIMNDLVVPCLPLLLVDEMEEKDMVAVEDMRNRWCSYLGQEMEPNLQEKLTDFLPKLLDCSTEIKSFHEPPKLPSYSTLELFERFGRVMTSLTMGRTPADGR---------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q01476-1", "uniprot_id": "UBP2_YEAST", "id": "Q01476-1", "name": "Ubiquitin carboxyl-terminal hydrolase 2", "aln": "MPNEDNELQKAIENHHNQLLNQDKENADRNGSVIEDLPLYGTSINQQSTPGDVDDGKHLLYPDIATNLPLKTSDRLLDDILCDTIFLNSTDPKVMQKGLQSRGILKESMLSYSTFRSSIRPNCLGSLTDQVVFQTKSEYDSISCPKYNKIHVFQAVIFNPSLAEQQISTFDDIVKIPIYHLKVSVKVRQELERLKKHVGVTQFHSLDHLHEYDRVDLSTFDSSDPNLLDYGIYVSDDTNKLILIEIFKPEFNSPEEHESFTADAIKKRYNAMCVKNESLDKSETPSQVDCFYTLFKIFKGPLTRKSKAEPTKTIDSGNLALNTHLNPEWLTSKYGFQASSEIDEETNEIFTEYVPPDMVDYVNDLETRKIRESFVRKCLQLIFWGQLSTSLLAPNSPLKNTKSVKGMSSLQTSFSTLPWFHLLGESRARILLNSNEQTHSPLDAEPHFINLSVSHYYTDRDIIRNYESLSSLDPENIGLYFDALTYIANRKGAYQLIAYCGKQDIIGQEALENALLMFKINPKECNISELNEATLLSIYKYETSNKSQVTSNHLTNLKNALRLLAKYTKSDKLKFYVDHEPYRALSQAYDTLSIDESVDEDIIKTAYSVKINDSPGLKLDCDRALYTIAISKRSLDLFNFLTEECPQFSNYYGPE-KLDYQEALKLLQVNENASDETILKIFKQKWFDENVYEPDQFLILRAALTKISIERNSTLITNFLLTGTIDPNSLPPENWPTGINNIGNTCYLNSLLQYYFSIAPLRRYVLEYQKTVENFNDHLSNSGHIRRIGGREISRGEVERSIQFIYQLRNLFYAMVHTRERCVTPSKELAYLAFAPSNVEVEFEVEG-------------NKVVDQTGVLSDSKKETTDDAFTTKIKDTSLIDLEMEDGLNGDVGTDANRKKNESN-----------------DAEVSENEDTTGLTSPTRVAKISSDQLENALEMGRQQDVTECIGNVLFQIESGSEPIRYDEDNEQYDLVKQLFYGTTKQSIVPLSATNKVRTKVERFLSLLINIGDHPKDIYDAFDSYFKDEYLTMEEYGDVIRTVAVTTFPTILQVQIQRVYYDRERLMPFKSIEPLPFKEVIYMDRYADTENPLLLAKKKETEEMKQKLKVMKNRQRELLSRDDSGLTRKDAFLESIKLLESDTIKKTPLKIEAANDVIKTLRNNVQNIDNELMKLYNDINSLEEKISHQFDDFKEYGYSLFSVFIHRGEASYGHYWIYIKDRNRNGIWRKYNDETISEVQEEEVFNFNEGNTATPYFLVYVKQGQEGDIEPLKRILK", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*. *:* **: ::*:* : :: .: * : ::: .. :: . **. .:.*. : :. *.* . : . :::: : *. . :* .: :*: :. ::: : . : :...: :: **: : . : :: .* : .... .: . : * :. :*: :. : .:..* . :.:. : ::* .: : . * . :: . . . .: ..* :. :. ::: ** :** . : ::*..: : *. : : . . :. ** :*:.:: : * . * . : ::. . . . . . ** * : * . : : : * . * ** : ** * :: :. *:* : ** : :* * . *: : : .: :::. : . .: . ::: . . . .: . . .. :. : *: . . :*.:. *:. : :.: : ** ::. :. *. : :: *: : *:*. :: : . ... : ::: : ::: :: : . * *: : * :::: : *. : : * : ::. *: .: * :. : : * : . .: :: : . :.: :: : : : ..:: :. . : :. .:. : ::.:.: :*: * : :: * *. * ::* . * .** :.: * ::: * . :: :. .. : :: : ::. : * : ::***:: * * . : .. :* . : . .. * *::: : ::: .::: .:: * : : *. . : : : . . . .:: . .. :: * * : :* ", "identical_positions": 96, "similar_positions": 376, "identity": "7.37%" }, { "cls_id": "homologset.agr.MGI:1353656", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9QXA6-1", "uniprot_id": "BAT1_MOUSE", "id": "Q9QXA6-1", "name": "b(0,+)-type amino acid transporter 1", "aln": "------------------MEETSLRRRRED-----------------------------------------EKSTHST---ELKTTSLQKEVGLLSGICIIVGTIIGSGIFISPKSVLANTES-VGPCLIIWAACGILATLGALCFAELGTMITKSGGEYPYLMEAFGPIPAYLFSWTSLIVMKPSSFAIICLSFSEYVCAAFYSGCKPPAVVVKLLAAAAILFITTVNALSVRLGSYVQNVFTAAKMVIVAIIIISGLVFLAQG-----NVKNFQNSFEGTQTSVG--AISLAFYNGLWAYDGWNQLNYITEELRNPYRNLPMAIVIGIPLVTVCYILMNIAYFTVMTPTELLQS-QAVAVTFGDRVLYP--ASWVVPLFVAFSTIGAANGTCFTAGRLIYVAGREGHMLKVLSYISVKRLT-PAPALIFYGIIAIIYIIP----GDINSLVN-YFSFAAWLFYGMTILGLVVMRFTRK----DLERPIKVPLFIPIIVILVSLFLILAPIISEPAWEYLYCVL-----------FILSGLIFYFLFVYYKFGWAQRISR-------------PVTKHLQMLMEVVPPEKDPE-----------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P82252-1", "uniprot_id": "BAT1_RAT", "id": "P82252-1", "name": "b(0,+)-type amino acid transporter 1", "aln": "------------------MEETSPRRRRED-----------------------------------------EKSVHST---EPKTTSLQKEVGLLSGICIIVGTIIGSGIFISPKSVLANTES-VGPCLIIWAACGVLATLGALCFAELGTMITKSGGEYPYLMEAFGPIPAYLFSWTSLIVMKPSSFAIICLSFSEYVCAAFYLGCRPPAVVVKLLAAAAILLITTVNALSVRLGSYVQNVFTAAKLVIVAIIIISGLVLLAQG-----NVKNFQNSFEGSQTSVG--SISLAFYNGLWAYDGWNQLNYITEELRNPYRNLPMAIVIGIPLVTVCYILMNIAYFTVMTPTELLQS-QAVAVTFGDRVLYP--ASWVVPLFVAFSTIGAANGTCFTAGRLIYVAGREGHMLKVLSYISVKRLT-PAPALVFYGIIAIIYIIP----GDINSLVN-YFSFAAWLFYGMTILGLVVMRFTRK----DLERPIKVPIFIPIIVILVSVFLILAPIISSPAWEYLYCVL-----------FILSGLIFYFLFVHYKFRWAQKISR-------------PITKHLQMLMEVVPPEKDPE-----------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P82251-1", "uniprot_id": "BAT1_HUMAN", "id": "P82251-1", "name": "b(0,+)-type amino acid transporter 1", "aln": "------------------MGDTGLRKRRED-----------------------------------------EKSIQSQ---EPKTTSLQKELGLISGISIIVGTIIGSGIFVSPKSVLSNTEA-VGPCLIIWAACGVLATLGALCFAELGTMITKSGGEYPYLMEAYGPIPAYLFSWASLIVIKPTSFAIICLSFSEYVCAPFYVGCKPPQIVVKCLAAAAILFISTVNSLSVRLGSYVQNIFTAAKLVIVAIIIISGLVLLAQG-----NTKNFDNSFEGAQLSVG--AISLAFYNGLWAYDGWNQLNYITEELRNPYRNLPLAIIIGIPLVTACYILMNVSYFTVMTATELLQS-QAVAVTFGDRVLYP--ASWIVPLFVAFSTIGAANGTCFTAGRLIYVAGREGHMLKVLSYISVRRLT-PAPAIIFYGIIATIYIIP----GDINSLVN-YFSFAAWLFYGLTILGLIVMRFTRK----ELERPIKVPVVIPVLMTLISVFLVLAPIISKPTWEYLYCVL-----------FILSGLLFYFLFVHYKFGWAQKISK-------------PITMHLQMLMEVVPPEEDPE-----------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F1QGJ2-1", "uniprot_id": "F1QGJ2_DANRE", "id": "F1QGJ2-1", "name": "b(0,+)-type amino acid transporter 1", "aln": "------------------MEEDLKKTKANNGS--------------------------------------VSRAVEAKNPDQPKAAVLHQDVGLLSGICLIVGTMIGSGIFISPKAVLEGTGA-VGPCLCVWAACGVLATLGALCYAELGTMIIKSGGEYPYLMEGFGPVLAYLYSWTTIIVLKPSSFAIIALSCAEYASTPFYPGCTPPQVVTKCLAAACILIITLVNCLSVKLAYRVQNFFTAAKLLIIIIIVVSGIVMLAQG-----NTQNLRDPFAGATTSFG--AIGLAFYNGLWAYDGWNQLNFITEELKNPYKNLPLAIIIGIPLVTVCYIMVNIAYFSVMTSTELLQS-SAVAVTFGDRVLYP--LSWIVPVFVVCSTFGAANGSCFTAGRLTYVAGREGHMVKIMSYISVKRYT-PSPALMFNGIVSIIYIMP----TDINTLIN-YFSFATWLFYGLTCLALIVMRFTRK----DLKRPVKVPIVIPALVVVVSCYLVLAPIIDKPEWEYLYCTM-----------FIVGGLLLYVPFIHYKFNWTRRLMR-------------PFTMHLQLLLQVVPPEKIE------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q8IR48-1", "uniprot_id": "Q8IR48_DROME", "id": "Q8IR48-1", "name": "b(0,+)-type amino acid transporter 1", "aln": "--------MRDKISQLFCLQKNACKNNSTDNNRGHNVPTKTTSNGTMCANGSLGTEGPEAPETDSSGTGRMRKPLERNGSTQNHVVHLERRLGLFSGVALIVGTMIGSGIFVSPSGLLVRTGS-VGVSFIIWLACGVLSLLGALAYAELGTMNTSSGAEWAYFMDAYGPAPAFLFSWVSTLVLKPSQMAIICLSFAQYAVEAFVTECDPPRGVVKMVALVAIVMILFVNCYSVNLGMAVQNVFTAAKLVAVVVVICGGAWKLMQG-----NTQHLSNAFNGPMPNVG--AIATAFYTGLWAYDGWNNLNYVTEEIKNPSKNLPRSIIIGIPLVTLCYALINISYLAAMSPQEMIES-EAVAVTFGNRILGA--LAWLMPLSVTISTFGSANGTLFAAGRLCFAASREGHLLDILSYVHVRRLT-PAPGLIFHSLIASAMVLH----GTIDSLID-FFSFTAWIFYGGAMLALIVMRYTKP----NYPRPYKVPIIIPVVVLVISVYLVAAPIFETPRVEYLYALL-----------FIFAGLIFYVPFV--KLGMTPRFMN-------------KVTLFFQLLLEVVPTSSMAMFE---------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P50276-1", "uniprot_id": "MUP1_YEAST", "id": "P50276-1", "name": "High-affinity methionine permease", "aln": "-----MSEGRTFLSQLNVFNKENYQFSSSTTKKEVSNSTVDADNG--------------------------ASDFEAGQQFATELDQGEKQLGILSCIGLICNRMLGTGVFAVSSTIYTLCGS-VGLALIMWAVGAIIAISGLYVYMEFGTAIPKNGGEKNYLEAIFRKPKFFITCMYAAYIFFLGWAAGNSINTAIMFLTAADTEVTKWN--QRGIGVAVVFFAFLINSLNVKIGLYLQNILGIFKIGIVLFISITGWVALGGGLKDGYQSHNFRNAFEGTETATAY-GIVNALYSVIWSFVGYSNVNYALGEVKNPVRTLKIAGPTSMVFLAIIYIFVNIAYFAVVPKDKLISS-KLILAADFFDIVFGGQAKRAAAALVGLSALGNVLSVIFSQGRIIQQLGREGVLPFSNFFASSKPFNSPMVGLFQHFIVCTVTILAPP-PGDAYLLVQNLISYPMNIINFAISAGLLWIYWQRRQGKIEWNPPIKAGVFVTGFFTLSNLYLIIAPYVPPSNGESVYSSMPYWIHCVIAWGIFFFGGVYYVVWAQLLPRWGHYKLVSKDVLGEDGFWRVKIAKVYDDTIGDVDTQEDGVIETNIIEHYKSEQEKSL", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P38734-1", "uniprot_id": "MUP3_YEAST", "id": "P38734-1", "name": "Low-affinity methionine permease", "aln": "MEPLLFNSGKANPSQDVFIDVEVGDITTKYGSTNTGSFSSMDT---------------------------VEAQAIKAETARFMEVPQGRHLGVFSTVVLFVSRIMGSGIFAVPSVILLNTGGNKLIYFAIWVFSAAIAFAGLYLFLEFGSWIPKSGGRKNFLERSFERPRLLISVVFSCYSVLTGYALTGSIVFGKYVLSAFGVTDDSWS---KYVSISFIIFAVLIHGVSVRHGVFIQNALGGLKLIMIVLMCFAGLYTLFFYKSTGQVAWDLPVTQVEKDSLLSVSSIATAFISSFFCFSGWDTVHTVTSEIKNPVKTLKVSGPLSLIICFVCYTMMNVAYLKVLTYEEIVSAGPLVGSVLFTKLFGPRVGGKFIAFSIAISAASNILVVIYSISRVNQEIFKEGYLPFSIHMSKNWPFDAPLPSISLCGFITIAWILILPKEGESFNYLVSMDGYGNQFFLLLVAIGLFIWRFKHK----NEVPEIRASTFGVLAIITLSLYMLMAPFFADPSLNRVGFLPP---YQIMSLLVIVACFFFWLVKFVLLPKFFHYKLLP------------KITYLHDGLIVTEWVKKPCLC----------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : :*::* : :: . ::*:*:* .. : . : :* . :: * : *:*: ..*.. :: : : : . .: . . : :. :.: :: .*. . :** : *: : .: * * .: . . .* *: . ::.: *:. :: *::** :.* : .: : * ::*::*: .:. :::.: : . :. . : *: . :: .*: :** : * .: :: :: : .: :: .*. : : : :. . . . ::: ** . . : : .:. . :. .: : : .. ", "identical_positions": 34, "similar_positions": 146, "identity": "5.56%" }, { "cls_id": "homologset.agr.MGI:1353657", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O88842-1", "uniprot_id": "FGD3_MOUSE", "id": "O88842-1", "name": "FYVE, RhoGEF and PH domain-containing protein 3", "aln": "MELGRSSSTPQEEAISPLGVLGTGPSSSPLGKLQALPIGPGAHRGAHSSSAPAGDSS-----TREPSGAMKIPNRDSGIDSPSSSVASENFPCEESSEGSPSPAILGLPSETASDSRVPQDNPQEEEDSGVGEEPDPKVTLFRPQEDVSLTQCSDPQKLLHIAQELLHTEEAYVKRLHLLDQVFCTKLTEAGIP-LEVTTGIFSNISSIYRFHGQFLLPELQKRITEEWDTNPRLGDILQKLAPFLKMYGEYVKNFDRAMGLVSTWTQRSPQFKDVIHTIQKQEVCGNLTLQHHMLEPVQRVPRYELLLKDYLKRLPRDAPDRKDAERSLELISTAADHSNAAIRKMEKMHKLLEVYEQLGGEE-DIVNPANELIKEGSIQKLSAKNGTTQDRHLFLFNNVMLYCVPKLRLMGQKLSVREKMDISDLQVQDIVKPNAACT--FIITGRKRSLELQTRTEEEKKEWIQVIQATVEKHKQKSETFRAFGGACSQDEEPTLSPDQPVMSTSSVEPAGVADSNGGTPGIESRKSSSKTRRDKEKPGCKSCGETFNSITKRRYRCKLCGEVICRKCSEFKAENSKQSRVCRECFLEEPLVPPSPSSETPTELKQNAEKPPSVDPRPSLLCGTLNLSDDGTT-WNEVWAAIPESDPQVLDLLAGSQAGRLLYSIPLSGCNITMPDPEEGLEAGCAWKLHQGSQTWWLSAPSTK--LQQCWLKALGTAVHGDTAGDRPGASQPQAPAGTDTP---------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A0G2K2U9-1", "uniprot_id": "A0A0G2K2U9_RAT", "id": "A0A0G2K2U9-1", "name": "FYVE, RhoGEF and PH domain-containing protein 3", "aln": "MELGRSSPTPQEEAISPLGVPDAGLRSSPLGKLQALPFGSGAPQGAQGSSASAGDSS-----LGEPSGAMKIPNRDSGIESPSSSVASENFPCEEGSEGSPSPAILGLHPEVAVDSRAPQDNPQEGEDSGVGEDPDPKITPCRPEEDVGSTQCSDPQKLLHIAQELLHTEEAYVKRLHLLDQVFCAKLTEAGIP-PEVTTGIFSNISSIYRFHGQFLLPGLKKRITEEWDTKPRLGDILQKLAPFLKMYGEYVKNFDRAMGLVSTWTQRSPQFKDVIHTIQKQEVCGNLTLQHHMLEPVQRVPRYELLLKDYLKRLPRDAPDRKDAERSLELISIAADHSNAAIRKMEKMHKLLEVYEQLGGEE-DIVNPANELIKEGNIQKLSAKNGTTQDRHLFLFNNVMLYCVPKLRLMGQKFSVREKMDISDLQVQDVVKPNAART--FIITGRKRSLELQTRTEEEKKEWIQVIQATVEKHKQKSETFRAFSGACTQEEEPSLSPDQPVLSAGPVEPAGVADSSGGTPGIESRKLSSKTRRDKEKPGCKSCGETFNSITKRRYRCKLCGEVICRKCSEFKAENSKQSRVCRECFLEEPLLPTSPSSETPTELKQNAEKPPSVDPRPSLLCGTLNLSDNGTA-WSEVWAAIPESDPQVLDLLAGSQAGKLLYSIPLSGCNITVPDPEEGLEAGYVWKLHQGSQTWWLSAPSTK--LQQRWLEALSTASRGDTAGDTPGASQPQTPASTDTP---------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q5JSP0-1", "uniprot_id": "FGD3_HUMAN", "id": "Q5JSP0-1", "name": "FYVE, RhoGEF and PH domain-containing protein 3", "aln": "MESGRGSSTPPG-PIAALGMPDTGPGSSSLGKLQALPVGPRAHCGDPVSLAAAGDGSPDIGPTGELSGSLKIPNRDSGIDSPSSSVAGENFPCEEGLEAGPSPTVLGAHAEMALDSQVPKVTPQEEADSDVGEEPDSENTPQKADKDAGLAQHSGPQKLLHIAQELLHTEETYVKRLHLLDQVFCTRLTDAGIP-PEVIMGIFSNISSIHRFHGQFLLPELKTRITEEWDTNPRLGDILQKLAPFLKMYGEYVKNFDRAVGLVSTWTQRSPLFKDVVHSIQKQEVCGNLTLQHHMLEPVQRVPRYELLLKDYLKRLPQDAPDRKDAERSLELISTAANHSNAAIRKVEKMHKLLEVYEQLGGEE-DIVNPANELIKEGQIQKLSAKNGTPQDRHLFLFNSMILYCVPKLRLMGQKFSVREKMDISGLQVQDIVKPNTAHT--FIITGRKRSLELQTRTEEEKKEWIQIIQATIEKHKQNSETFKAFGGAFSQDEDPSLSPDMPITSTSPVEPVVTTEGSSGAAGLEPRKLSSKTRRDKEKQSCKSCGETFNSITKRRHHCKLCGAVICGKCSEFKAENSRQSRVCRDCFLTQPVAPES------------TEKTPTADPQPSLLCGPLRLSESGET-WSEVWAAIPMSDPQVLHLQGGSQDGRLPRTIPLPSCKLSVPDPEERLDSGHVWKLQWAKQSWYLSASSAE--LQQQWLETLSTAAHGDTAQDSPGALQLQVPMGAAAP---------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VS45-1", "uniprot_id": "Q9VS45_DROME", "id": "Q9VS45-1", "name": "", "aln": "----------------------------------------------MFTPRQKGYGN----------GFIHSPQTPLSFSRELRQVLQERNLLTAKSRRK-------VCSMLDSNNSSPIGSPNPDAGKRLGFRR-------------------------QAIQEIISSEKSYLEQLELLMNFFVRPLKEQAIIDCSNHTLLFGQIEMIHNLNGEFLR--------ELEANMENVAHAFLKMAPFFKLYSVYAFDYRGALFIIQDLISKNPVFRKFLEQTESRPEVQ-RKLNSLMIVPIQRVPRYKLLLEQVLLYTSPADADYKLLKESVKEIEATASHINTCVEEQEITQYLIHLQNSLVNRTPNIVKPSRRVIKEGVLQKITHK-GTEIKRYCVLMSDIFMYCK-MIKERAPNTVVENSLECCCIFPLKKCKVYEMLPGNFKLTCQSDGIIFGSGDVQLSRTWVGFIRDAIDLHVQCRKTLRKD----SSKRTPIRKKDMKKFGADYVLSPNKRKCEYDTV-FRNKNRSTDSEEETEDSACFSRKRKVASGILRAPNGNPMGKASSSSSSSVSMKRVAPP---PPAPPPPPAVQMRHQPGRPGELATASKENRISKLYKKIAAGDKVANVRGILKRSNVPAPNNDHDPSYGFASRYSDSKSYFRAHNVDNTIPTFVKREDLFNGDNMFPVHLKSHEEICTPPQKKRVKFDDTLDAVSPVLVEKPFAFSSESSSALKPTSLRERIYDFFANLF", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : * .. * :: *: .:. .* *. . . :. * .*: .. :* : **:: :*::*:::*.** :.* *.: .* . :*.:*. *:.::*:** * . .:.. : *:***:*:*. *. :: *: ::. .:.* *:..:. :.: .*: *: *:******:***:: * . .* * :.*:: *. :*.* *:.:.: * : *:.: :.* .. :**:*:..:**** :**:: * ** .*: .*:..:::** :: . : *.:.:: . : . * . * :* :. .: : : : .: *: .*: ::: * * :*:: :... * . * .:. * . . . .: :. :: *:.:..:.*. .* * ... * * . : * . . ..*... :. . . * ::: . .: .* . * .:* *. **. *: : : . :. . *: ::.. : :: .: :... : : *.::... .. . : . * . ", "identical_positions": 105, "similar_positions": 241, "identity": "13.93%" }, { "cls_id": "homologset.agr.MGI:1353659", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q5XIA3-1", "uniprot_id": "TYW4_RAT", "id": "Q5XIA3-1", "name": "tRNA wybutosine-synthesizing protein 4", "aln": "--------------MGPRSRQRRTGTVQSTNDSSSLSKR---------SLAAQGYVSDA------FAPLLVPGIVRRTPLIHRGYYVRARAVRHCVRAFLDLTGAIRSPTRAQILSLGSGSDSLYFRLKAAG------LLTRTAVWEVDFPDVSRLKAKRIEETPELCAQTGPFKIG---DSASTLCFESSDYRILGADLRELQRLGEALDSAGL-DATSPTLILAEAVLTYLEPSRAAALIAWVAQRFPNALFVIYEQMKPG---DAFGQIMLQHFRRLNSPLHGLELFPDVEAQRQRFLQAGWTTCSALDLNEFYRRLIPADERRRVETLEPFDEFEEWHLKCSHYFILAASRGDILSETPVFLPSEASFQIDPALPSGFLSASVVTSDHQHSSLQRYGHTSVLLSPGIIFSAGGFGEQEGRHCRVSRFHLLSRSCDSEWKGCQISTLGTEGQWDGRLYHTMTRLS-DTRVLVLGGRLSPVNPASGALQLDIYKSEDNCPEGQNVVVTKAALEEGSMLSCWRHSTTEVYYQNQRYLFVYGGRSVTDPVLSDCRFLHVETMAWVRIPVQGSSPEGRHSHSACSWQGGALIAGGLGASEEPLSSVFFLRPVS--SGFLWESIHIQPSITPRY-SHTAHVFNGKLLLVGGVWIHSSSVPGVTVISLTTGLSSEYQIDTASVPWP--LMLHNHSSALLPEEQQLLLIGGGGNCFSFGTYFNPHTVGLDLSSLGLGQ", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8BYR1-1", "uniprot_id": "TYW4_MOUSE", "id": "Q8BYR1-1", "name": "tRNA wybutosine-synthesizing protein 4", "aln": "--------------MGPRGRQRRAGTVQSTNDSSSLSKR---------SLAAHGYVRDP------FAALLVPGPVRRTPLIHRGYYVRARAVRHCVRAFLELTSALPSRTRAQILSLGSGSDSLYFRLKAAG------LLARAAVWEVDFPDVSRLKAERIEETPELRAQTGPFKIG---DSASSLCFESADYRILGADLRELQRLGEALDGAGL-DATSPTLLLAEAVLTYLEPSSATALIAWAAQRFPDALFVIYEQMQPG---DAFGQIMLQHFQRLHSPLHGLELFPVVKAQRQRFLQAGWTACSALDLNEFYRRLLSAEERQRVETLEPFDEYEEWHLKCSHYFILAASRGDILSETPVFEPSEASFQIDPASPSGFLSARVVTSDHQHSSLKRYGHASALLSPGVIFSAGGFGEQEGRHCRVSRFHVLSRSCDSEWEGCQISTLGTEGQWDGRLYHTMTRLS-DTRVLVLGGRLSPVSPASGALQLDLYKSKDNCSEGQNVTVTKAALEEGSVLSCWRHSTTEVYYQNQRYLFVYGGRSVAEPVLSDCRFLHVETMAWVRIPVQGASPEGRHSHSACSWQGGALIAGGLGASEELLSSVLFLKPVS--SGFLWESIDIQPSITPRY-SHTAHVFNGKLLLVGGVWIHSSSVPGVTVICLTTGLSSEYQIDTASVPWP--LMLHNHSSALLPEEQQLLLIGGGGNCFSFGTYFNPHTVALDLSSLRSGQ", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O60294-1", "uniprot_id": "TYW4_HUMAN", "id": "O60294-1", "name": "tRNA wybutosine-synthesizing protein 4", "aln": "--------------MGPRSRERRAGAVQNTNDSSALSKR---------SLAARGYVQDP------FAALLVPGAARRAPLIHRGYYVRARAVRHCVRAFLEQIGAPQAALRAQILSLGAGFDSLYFRLKTAG------RLARAAVWEVDFPDVARRKAERIGETPELCALTGPFERG---EPASALCFESADYCILGLDLRQLQRVEEALGAAGL-DAASPTLLLAEAVLTYLEPESAAALIAWAAQRFPNALFVVYEQMRPQ---DAFGQFMLQHFRQLNSPLHGLERFPDVEAQRRRFLQAGWTACGAVDMNEFYHCFLPAEERRRVENIEPFDEFEEWHLKCAHYFILAASRGDTLSHTLVFPSSEAFPRVNPASPSGVFPASVVSSEGQVPNLKRYGHASVFLSPDVILSAGGFGEQEGRHCRVSQFHLLSRDCDSEWKGSQIGSCGTGVQWDGRLYHTMTRLS-ESRVLVLGGRLSPVSPALGVLQLHFFKSEDNNTEDLKVTITKAGRKDDSTLCCWRHSTTEVSCQNQEYLFVYGGRSVVEPVLSDWHFLHVGTMAWVRIPVEGEVPEARHSHSACTWQGGALIAGGLGASEEPLNSVLFLRPIS--CGFLWESVDIQPPITPRY-SHTAHVLNGKLLLVGGIWIHSSSFPGVTVINLTTGLSSEYQIDTTYVPWP--LMLHNHTSILLPEEQQLLLLGGGGNCFSFGTYFNPHTVTLDLSSLSAGQ", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q08282-1", "uniprot_id": "TYW4_YEAST", "id": "Q08282-1", "name": "tRNA wybutosine-synthesizing protein 4", "aln": "MKNLTTIKQTNKNVKQERRKKYADLAIQGTNNSSIASKRSVELLYLPKLSSANNFQMDKNNKLLEYFKFFVPKKIKRSPCINRGYWLRLFAIRSRLNSIIEQT---PQDKKIVVVNLGCGYDPLPFQLLDTNNIQSQQYHDRVSFIDIDYSDLLKIKIELIKTIPELSKIIGLSEDKDYVDDSNVDFLTTPKYLARPCDLNDSKMFSTLLNECQLYDPNVVKVFVAEVSLAYMKPERSDSIIEATSK-MENSHFIILEQLIPKGPFEPFSKQMLAHFKRNDSPLQSVLKYNTIESQVQRFNKLGFAYVNVGDMFQLWESADEAT-KKELLKVEPFDELEEFHLFCHHYVLCHATNYKEFAFTQGFLFDRSISEINLT-----VDEDYQLLECECPINRKFGDVDVAGN-DVFYMGG------SNPYRVN--EILQLSIHYDKIDMKNIEVSSSEVPVARMCHTFTTISRNNQLLLIGGRKAPHQGLSDNWIFDMKTREWSMIKS---------------LSHTRFRHSACSLPDGNVLILGGVTEGPAMLLYNVTEEIFKDVTPKDEFFQNSLVSAGLEFDPVSKQGIILGGGFMDQTTVSDKAIIFKYDAENATEPITVIKKLQHPLFQRYGSQIKYITPRKLLIVGGTSPSGLFDRTNSIISLDPLSETLTSIPISRRIWEDHSLMLAGFSLVSTSMGTIHIIGGGATCYGFGSVTN---VGLKLIAIAK--", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * :: ::*.**:** *** :*..: * : ::** :*:* *:***::* *:* :.:::: : ::.**.* *.* *:* :. *.:. ::*:.*: : * : * *** * : : :. : :..* **.: : . *. . * *. .:::**. *:*::*. : ::* .:: : :: *:: **: * :.*.: ** **:: .***:.: : :::* :** : *:: .. *: :::. * ::.: .:***** **:** * **.: *:. . :: * * ..: .:: : . : : . :::*.... . .:: .* .. **. .:*. . . : . : .: .*: **:* :* :.::*::*** :* . . :.: . : . :. *. *. : : . *:: * . :* : . :: .:. .. .... : ** * .* :. : .:::* . : .:* .: ** *: :: ***:*** . ::* * . .: .* : * :: * : .. : ::***..*:.**: * * *.* :: ", "identical_positions": 133, "similar_positions": 241, "identity": "18.12%" }, { "cls_id": "homologset.agr.MGI:1353665", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9QZL6-1", "uniprot_id": "UBP21_MOUSE", "id": "Q9QZL6-1", "name": "Ubiquitin carboxyl-terminal hydrolase 21", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MPQASEHRLGRTREPPVNVQPRVGAKIPFPPRARSKERRNPVPGP-------NSMLRPLPPRPGPPDERLKKLELGRGRTSGSRPRGPLRADHGVPLPGSPPPAVALPLPSRTNLARSKSVSSGDLRPMGIALGGHRGAGELGAALSRLALRPEPPTLRRSTSLRRLGGFPGPPTLLSIRTEPPTSHGSFHMISARPSEPFYSDDKMAHHTLLLGS----------------GHVGLRNLGNTCFLNAVLQCLSSTRPLRDFCLRRDFRQEV---PGGGRAQELTEAFADVIGALWHPDSCEA-------VNPTRFRAVFQKYVPSFSGYSQQDAQEFLKLLMERLHLEINRRGRRAPPILASGPVPSPPRRGGGALHEEPELSDDDRANLMWKRYLEREDSKIVDLFVGQLKSCLKCQACGYRSTTFEVFCDLSLPIPK-KGFAGGKVSLRDCFSLFTKEEELESENAPVCDRCRQKTRSTKKLTVQRFPRILVLHLNRFSTSRGSIKKSSVGVDFPLQR-------------LSLGDFASDKAGSPVYQLYALCNHSGSVHYGHYTALCRCQTG--WHVYNDSRVS-PVSENQVASSEGYVLFYQLMQEPLRCL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "B2GUX4-1", "uniprot_id": "UBP21_RAT", "id": "B2GUX4-1", "name": "Ubiquitin carboxyl-terminal hydrolase 21", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MPQASEHRLGRTREPPVNVQPRVGAKIPFPPRARSKERRNPVPGP-------NSMLRPLPPRPGPPDERLKKLDLGRGRTSGSRPRGPLRADHGVPLPGSPPPTVALPLPSRTNLTRSKSVSSGDLRPMGIALGGHRGTGELGAALSRLALRPEPPTLRRSTSLRRLGGFPGPPTLLSIRTEPPPSHGSFHMISARPSEPFYSDDKMAHHTLLLGS----------------GHVGLRNLGNTCFLNAVLQCLSSTRPLRDFCLRRDFRQEV---PGGGRAQELTEAFADVIGALWHPDSCEA-------VNPTRFRAVFQKYVPSFSGYSQQDAQEFLKLLMERLHLEINRRGRRAPPILASGPVPSPPRRGG-ALHEEPELSDDDRANLMWKRYLEREDSKIVDLFVGQLKSCLKCQACGYRSTTFEVFCDLSLPIPK-KGFAGGKVSLRDCFSLFTKEEELESENAPVCDRCRQKTRSTKKLTVQRFPRILVLHLNRFSTSRGSIKKSSVGVDFPLQR-------------LSLGDFASDKVGSPVYQLYALCNHSGSVHYGHYTALCRCQTG--WHVYNDSRVS-PVSENQVASSEGYVLFYQLMQEPPRCL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9UK80-1", "uniprot_id": "UBP21_HUMAN", "id": "Q9UK80-1", "name": "Ubiquitin carboxyl-terminal hydrolase 21", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MPQASEHRLGRTREPPVNIQPRVGSKLPFAPRARSKERRNPASGP-------NPMLRPLPPRPGLPDERLKKLELGRGRTSGPRPRGPLRADHGVPLPGSPPPTVALPLPSRTNLARSKSVSSGDLRPMGIALGGHRGTGELGAALSRLALRPEPPTLRRSTSLRRLGGFPGPPTLFSIRTEPPASHGSFHMISARSSEPFYSDDKMAHHTLLLGS----------------GHVGLRNLGNTCFLNAVLQCLSSTRPLRDFCLRRDFRQEV---PGGGRAQELTEAFADVIGALWHPDSCEA-------VNPTRFRAVFQKYVPSFSGYSQQDAQEFLKLLMERLHLEINRRGRRAPPILANGPVPSPPRRGG-ALLEEPELSDDDRANLMWKRYLEREDSKIVDLFVGQLKSCLKCQACGYRSTTFEVFCDLSLPIPK-KGFAGGKVSLRDCFNLFTKEEELESENAPVCDRCRQKTRSTKKLTVQRFPRILVLHLNRFSASRGSIKKSSVGVDFPLQR-------------LSLGDFASDKAGSPVYQLYALCNHSGSVHYGHYTALCRCQTG--WHVYNDSRVS-PVSENQVASSEGYVLFYQLMQEPPRCL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M2B8Z0-1", "uniprot_id": "A0A8M2B8Z0_DANRE", "id": "A0A8M2B8Z0-1", "name": "Ubiquitin carboxyl-terminal hydrolase", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MPRAESTSMDN----------------------------------------------------------------------SCQALYRTLVTQNG--------------------------LQPENVDISQSVLYTSIMG--------------------LLLVTDKERE------------LQLGN----------------GQVGLRNVGNTCFLNAIVQCLSHTRSLRDYCLMRAYVQDK---HSN-QEPVLMDEFSKVLAGLWECDAGETT------VNPGKFYRVFKESVPYFSGYSQQDAQEFLRFLLDRLHTEINRRPSKRPAVIERKEPAYTRFRIS------------EEAFAMWQRHLDRDDSKIVDLFSGQLRSSLHCSVCSHYSNTFDVFCDLSLPIPKQKSDYGRAVTLRECLDLFSQEEKLDKENSPMCERCNRRTESTKRLTIQRFPRVLVIHLNRFAMSRFSISKSTVPVSFPLTA-------------LDLGLFGPVDCGPVLYDLYAVCNHSGTVNMGHYTAACREEEG--WCFYNDSCVD-AISEEKLQSNQAYVLFYELKSCNISRK", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q8IQ27-1", "uniprot_id": "UBP2_DROME", "id": "Q8IQ27-1", "name": "Ubiquitin carboxyl-terminal hydrolase Usp2", "aln": "MMLDIKKTRGFHKIPQASKLQSTTKTSSVVATSASSQNEVPSPGGSAGSKVGATNPVRAANQRFFLVSSYKDPTFLKAECDLAHAHVTTSKVKTTLQPHRRSRAGEDSRNNNYNTSRAPTLINMRRPSLFNGNQQPTTTNSTTINNTTSRNTTSNTSNGVLKYSVRSTTATATSTSTRNYGKLKPLNNNQTTAGVAMMNGHTNNNNNNTRNSSNINNGGNNNMQRQQQQHDDISFIDSDDPPATGGPEAGISTTKTSICYFKPITPPLQLRHEQNQVQQQEEQPQPSSSKSASHRYPRPKSTIIASAHSNFAASFEKFSGGLYRQTNGETNIESKTSSNARRYGIDSLSIKASIEKFNNLSGQKRQNPGSGSGIGPGSATASGLGGGRLSVASRSNHGSQAGGSSSNLQQRYSSDLDNIRVAAGYSSSLTRAAYRTTATMNSVSTPVAVTSELGGPISGDGGETATAMGQPTSKVTVRGAHSNRQPIECDSVVLTNKASKDATTAATPTVATATATHTPATSSVSTVTVTAAAPNSASDSTLARSGTGSSSTARSVLPPMTPTSSRYWDRDSGTSRSSIGTSSALNSSSLKHNSDDGYKTASSSRDEKSEGLCGLRNIGNTCFMNSVIQCLSHTQELTR--FLRSHHGSR---SLSTKDQQILHEFAKLIQEMWTAN--VHT------VTPMELKRAFSTKHRMYSDYNQQDAQEFLRFFLDSLHSALNSGVKGETLNIDDNLSDN------------------KKADLTWEWYTRHENSLVRDLFVGQLKSTLKCTTCGNTSVTFDPFWDLSVPLPS-----SSRCKLEACLDLFIREEVLDGDEMPTCAKCKTRRKCTKSFTIQRFPKYLVIHLKRFSETRWSKLSNIVEFPTSDSE-------------LNMGSYGANSNSNVHYSLYAISNHMGSTAGGHYVALCKHPVSRKWHEFNDNIVSDALSENHLVSSSAYILFYERT-------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P39944-1", "uniprot_id": "UBP5_YEAST", "id": "P39944-1", "name": "Ubiquitin carboxyl-terminal hydrolase 5", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------MGSEQALSEVVESAKERFGRLRHLVQKFLDDDDVPQECLPLLQECAEIWSSYVDACQDITMQAPKEDANRLSKGFLRLNETAFLYYMIVYTLLEDTLPRLKEFSSNKDQNVRNLYGERIQLLHNDPNIERIRNVIENYPKFIQLQTIEPGKLSSMLHFHGDALLLIDVRPRSEFVRAHIKCKN----IICIDPASFKDSFTDQQIESVSLITSPHSDITFFSNRDKFKFIILYTDTQLHNNFQQRQTRILAKILSQNSVIKPLSGTKILILENGFSNWVKLG------------GAYQSSVSETAHLTSSSSTPAFGSPQVPTGLFNQKSLSPNKDKSMPMVSMNTQPLLTTVQRPQLPLYYSDLPIIPQPSPNRNSPTVQKFSPHPPTTLSKLNTPSTIQNKANTVERISPDIRAAQAHAYLPPASNVFSPRIPPLPQQNLSSSRQTILNNSQVLDLD--------------LIVGLENIGNCCYMNCILQCLVGTHDLVRMFLDNTYLNFINFDSSRGSKGLLAKNFAILVNNMHRHGAFTPPNVRTIPVQTIQFKKICGHINPMYSDSMQQDCQEFCQFLLDGLHEDLNQNGSKKHLKQLSDEEERMREKMS----------IRKASALEWERFLLTDFSAIIDLFQGQYASRLQCQVCEHTSTTYQTFSVLSVPVPR-----VKTCNILDCFREFTKCERLGVDEQWSCPKCLKKQPSTKQLKITRLPKKLIINLKRFDN-QMNKNNVFVQYPYSLDLTPYWARDFNHEAIVNEDIPTRGQVPPFRYRLYGVACHSGSLYGGHYTSYVYKGPKKGWYFFDDSLYRPITFSTEFITPSAYVLFYERIF------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . *. .. . . . . **.*:** *::*.::*** *: * : . . : . *: :: : . * . .: :*. ***.*** ::::: ** :* . : *: . : * : *** ** * *:* .* * *:: * **:*:* .: *: * : * * :: * :* : .** :.: *:*: *:::*:** : . . * . :. . . * **.:. * *: ***.: * ::*. . .. : ..*:***: ", "identical_positions": 72, "similar_positions": 93, "identity": "7.24%" }, { "cls_id": "homologset.agr.MGI:1354159", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D4ACR8-1", "uniprot_id": "D4ACR8_RAT", "id": "D4ACR8-1", "name": "", "aln": "------------------------------------MSQQRTAR----------KLP----------SLLVDPAQET--VRRRCRDP-----INVENLLPSKIRIN---------------------------------------------------------------LEENVQY---------------VSMRKALKVKR--------------------------------------------------PRFDVSLVYLTRKFMDLVRSAPGGILDLNKVATKLGVRKRRVYDITNVLDGIELVEKKSKNHIRWIGSD-LNNFGAAPQQKKLQAELSDLSAMEDALDELIKDCAQQLLELTDDKENER-LAYVTYQDIHGIQAFHEQIVIAVKAPEETRLDVPAPREDSITVHIRSTKGPIDVYLCEVEQNHSNGKTA----------------------------------DGVGASPSD----------SKHLQSPEK---EDKPLQ--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O54917-1", "uniprot_id": "E2F6_MOUSE", "id": "O54917-1", "name": "Transcription factor E2F6", "aln": "------------------------------------MSQQRTAR----------RQP----------SLLVDPAQET--VRRRCRDP-----INVENLLPSKIRIN---------------------------------------------------------------LEENVQY---------------VSMRKALKVKR--------------------------------------------------PRFDVSLVYLTRKFMDLVRSAPGGILDLNKVATKLGVRKRRVYDITNVLDGIELVEKKSKNHIRWIGSD-LNNFGAAPQQKKLQAELSDLSAMEDALDELIKDCAQQLLELTDDKENER-LAYVTYQDIHGIQAFHEQIVIAVKAPEETRLDVPAPREDSITVHIRSTKGPIDVYLCEVEQNHSNGKTN----------------------------------DGIGASPSK----------SSHPQCPEK---EDEPPQ--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O75461-1", "uniprot_id": "E2F6_HUMAN", "id": "O75461-1", "name": "Transcription factor E2F6", "aln": "------------------------------------MSQQRPAR----------KLP----------SLLLDPTEET--VRRRCRDP-----INVEGLLPSKIRIN---------------------------------------------------------------LEDNVQY---------------VSMRKALKVKR--------------------------------------------------PRFDVSLVYLTRKFMDLVRSAPGGILDLNKVATKLGVRKRRVYDITNVLDGIDLVEKKSKNHIRWIGSD-LSNFGAVPQQKKLQEELSDLSAMEDALDELIKDCAQQLFELTDDKENER-LAYVTYQDIHSIQAFHEQIVIAVKAPAETRLDVPAPREDSITVHIRSTNGPIDVYLCEVEQGQTSNKRS----------------------------------EGVGTSSSE----------STHPEGPEE---EENPQQSEELLEVSN-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0ACD6B6R4-1", "uniprot_id": "A0ACD6B6R4_DANRE", "id": "A0ACD6B6R4-1", "name": "", "aln": "-------------------------MVKCTVQGCINFSDLRPEEQPNRPRKRFFRFPKDKARVKVWLAALRDTEREITDLHRICEDHFLSHHITADGISPDAIPIMPPLDGPVGNWSSFEEEQDE------------------------HTGTLEESGAAADDDLEDEDFEDDEEYEDEGYIPADNNSNSTISKPQEQSVTQSFR-----------------------PIFSSPTIHPPVNVADDVFNSKAPHRSEVALGQLTKRFMQLLNAAPEGVLDLNEVSRKLGARKRRVYDITSVLAGIHLLKKTSKNKIQWMSSTPLSSFGSQWSP-KAKAELLHLKSTEEALDWLIKDCAQQLFALTDLKDNAD-SAYVTYEDICQIDVFKDQTIIAIRAPEETKLEVPTPTEESIKIHLKGSRGPIHTLTCETE-GPGDAEDS----------------------------------TNTESKLTK----------SDCFVSLEESRIQTQPLVPDVSNTVAAVQSA-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q27368-1", "uniprot_id": "E2F1_DROME", "id": "Q27368-1", "name": "Transcription factor E2f1", "aln": "MSKFFVNVAPINNSNSSSSHTTTSSNTQRHQQHQQHYGGSGTTGHTMVARRLNYDLHGGTTSINNNNNIVIKNESVDLDYDHVLSSSDSNSNGGVAAHLRDHVYISLDKGHNTGAVATAAAAATAGHTQQQLQQQHHHQNQQQRKATGKSNDITNYYKVKRRPHAVSDEIHPKKQAKQSAHHQTVYQKHTASSAPQQLRHSHHQLRHDADAELDEDVVERVAKPASHHPFSLSTPQQQLAASVASSSSSGDRNRADTSLGILTKKFVDLLQESPDGVVDLNEASNRLHVQKRRIYDITNVLEGINILEKKSKNNIQWRCGQ---SMVSQERSRHIEADSLRLEQQENELNKAIDLMRENLAEISQEVENSGGMAYVTQNDLLNVDLFKDQIVIVIKAPPEAKLVLPNTKLPREIYVKAENSGEINVFLCHDTSPENSPIAPGAGYVGAPGAGCVRTATSTRLHPLTNQRLNDPLFNNIDAMSTKGLFQTPYRSARNLSKSIEEAAKQSQPEYNNICDIAMGQHHNLNQQQQQQQQQLLQQPEEDDVDVELNQLVPTLTNPVVRTHQFQQHQQPSIQELFSSLTESSPPTPTKRRREAAAAAIAAGSSTTATTTLNSHNNRNHSNHSNHSNHSSSNNSKSQPPTIGYGSSQRRSDVPMYNCAMEGATTTSATADTTAATSRSAAASSLQMQFAAVAESNNGSSSGGGGGGGGYGSIAGAGANADPHQPYSHDRNSLPPGVADCDANSNSSSVTLQGLDALFNDIGSDYFSNDIAFVSINPPDDNDYPYALNANEGIDRLFDFGSDAYGP", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . . : . : . . . : * :. . : * : .: * :.:* **::*::*:. :* *::***:.: :* .:***:****.** **.:::*.***:*:* . .: : : : : *. *: *: *. ::* ::: :* **** :*: :: *::* :*.::** *::* :* . . * *.. *. . . : :. *: : :* ", "identical_positions": 55, "similar_positions": 86, "identity": "6.81%" }, { "cls_id": "homologset.agr.MGI:1354161", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I6APP5-1", "uniprot_id": "A0A8I6APP5_RAT", "id": "A0A8I6APP5-1", "name": "NAD-dependent protein deacylase sirtuin-6", "aln": "--------MCKARRVGHSDILEIFDPPEELECKVWELARLMWQSSTVVFHTGAGISTASGIPDFRGPHGVWTMEERGLAPKFDITFENARPSKTHMALVQLERMGFLSFLVSQNVDGLHVRSGFPRDKLAELHGNMFVEECPKCKTQYVRDTVVGTMGLKATGRLCTVAKARGLRACR-GELRDTILDWEDALPDRDLTLADEASRTADLSVTLGTSLQIRPSGNLPLATKRRGGRLVIVNLQPTKHDRQADLCIHGYVDEVMCKLMKHLGLEIPTWDGPRVLEKALPPLPRPVAPKAEP----PVHLNG----SYKPK-----------------PDSPVPHRPPKRVKTEAAAS-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P59941-1", "uniprot_id": "SIR6_MOUSE", "id": "P59941-1", "name": "NAD-dependent protein deacylase sirtuin-6", "aln": "MSVNYAAGLSPYADKGKCGLPEIFDPPEELERKVWELARLMWQSSSVVFHTGAGISTASGIPDFRGPHGVWTMEERGLAPKFDTTFENARPSKTHMALVQLERMGFLSFLVSQNVDGLHVRSGFPRDKLAELHGNMFVEECPKCKTQYVRDTVVGTMGLKATGRLCTVAKTRGLRACR-GELRDTILDWEDSLPDRDLMLADEASRTADLSVTLGTSLQIRPSGNLPLATKRRGGRLVIVNLQPTKHDRQADLRIHGYVDEVMCRLMKHLGLEIPAWDGPCVLDKALPPLPRPVALKAEP----PVHLNGAVHVSYKSK-----------------PNSPILHRPPKRVKTEAAPS-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8N6T7-1", "uniprot_id": "SIR6_HUMAN", "id": "Q8N6T7-1", "name": "NAD-dependent protein deacylase sirtuin-6", "aln": "MSVNYAAGLSPYADKGKCGLPEIFDPPEELERKVWELARLVWQSSSVVFHTGAGISTASGIPDFRGPHGVWTMEERGLAPKFDTTFESARPTQTHMALVQLERVGLLRFLVSQNVDGLHVRSGFPRDKLAELHGNMFVEECAKCKTQYVRDTVVGTMGLKATGRLCTVAKARGLRACR-GELRDTILDWEDSLPDRDLALADEASRNADLSITLGTSLQIRPSGNLPLATKRRGGRLVIVNLQPTKHDRHADLRIHGYVDEVMTRLMKHLGLEIPAWDGPRVLERALPPLPRPPTPKLEPKEESPTRINGSIPAGPKQEPCAQHNGSEPASPKRERPTSPAPHRPPKRVKAKAVPS-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VH08-1", "uniprot_id": "SIR6_DROME", "id": "Q9VH08-1", "name": "NAD-dependent protein deacetylase Sirt6", "aln": "MSCNYADGLSAYDNKGILGAPESFDSDEVVAEKCQELAELIKKSGHVVLHTGAGISTSAGIPDFRGPKGVWTLEEKGEKPDFNVSFDEARPTKTHMAIIALIESGYVQYVISQNIDGLHLKSGLDRKYLSELHGNIYIEQCKKCRRQFVSPSAVETVGQKSLQRACKSSMDSKGRSCRSGILYDNVLDWEHDLPENDLEMGVMHSTVADLNIALGTTLQIVPSGDLPLKNLKCGGKFVICNLQPTKHDKKANLIISSYVDVVLSKVCKLLGVEIPEYSEASDPTKQSKPMEWTIP---------TSNVN-------------------------------TFHRQYKKYVYFIYYLL", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :. * . * **. * : * ***.*: :*. **:********::********:****:**:* *.*: :*:.***::****:: * . * : :::***:****::**: *. *:*****:::*:* **: *:* :.* *:* *: * *. : *:** * * *.:****. **:.** :. * ***.::***:*** ***:*** . : **::** ********::*:* * .*** *: :: * **:*** :. . : *: . . . .:* ** *: ", "identical_positions": 136, "similar_positions": 83, "identity": "38.1%" }, { "cls_id": "homologset.agr.MGI:1354163", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZT95-1", "uniprot_id": "D3ZT95_RAT", "id": "D3ZT95-1", "name": "DNA repair endonuclease XPF", "aln": "---------------------------------------------MERGLPGERQSMAP--------------------------------LLEYERQQVLELLDSDGLVVCARGLGADRLLYHFLRLHCHPA--------CLVLVLNTQPAEEEYFINQLKIEGVEHLPR---------------------RVTNEIASNSRYEVYTQGGIIFATSRILVVDFLTGRIPSDLITGILVYRAHRIIESCQEAFILRLFRQKNKRGFIKAFTDNAVAFDTGFCHVERVMRNLFVKKLYLWPRFHVAVNSFLEQH----KPEVVEIHVSMTPAMLAIQTAILDVLNACLKELKYHNPSLEVEDLSLENALGKPFDKTIRHYLDPLWHQLGAKTKSLVQDLKILRTLLQYLSQYDCVTFLNLLESLRATEK----VFGQNSGWLFLDASTSMFVNARARVYRVPDVKLSKKTKTSEKMAGPEEQETKKELVLESNPKWEALTEVL-KEIETENKESEALGGPGQVLICASDDRTCCQLRDYLTAGAEAFLLRLYRKTFEKDGKAEEVWVNFRKGDGPKRTMKSDKRPKDAQNKERASTKRGALKRKKKRELTLTQVLGTAEEPPEEGAVEEDLHKQTGSS-------PEVCGGEI----------QHESFDLNVSSDAAYGILKEPLTIIHPLLG-CSDPYALTRVLHEVEPRYVVLYDAELTFVRQLEIYRASR---PGKPLRVYFFVYGGSTEEQRYLTALRKEKEAFEKLIREKASMVVPEEREGRDETNLDLAR--GTAAMDTPTDTRKAGGQE--RNGTQPSIVVDMREFRSELPSLIHRRGIDIEPVTLEVGDYILTPELCVERKSVSDLIGSLHSGRLYSQCLAMSRYYRRPVLLIEFDPSKPFSLAPRGAFVQEMSSS--------------DVSSKLTLLTLHFPRLRLLWCPSPHATAELFEELKQNKPQPDAATAMAITADSE------TLPE-SDRYNPGPQDFVLKMPGVNAKNCRSLMNQVQNIAELATLSLERLTGILGHSGNAKQLHDFLHTAYADLVSKGRVRK-----------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9QZD4-1", "uniprot_id": "XPF_MOUSE", "id": "Q9QZD4-1", "name": "DNA repair endonuclease XPF", "aln": "---------------------------------------------MEPGLSGERRSMAP--------------------------------LLEYERQQVLELLDSDGLVVCARGLGTDRLLYHFLRLHCHPA--------CLVLVLNTQPAEEEYFINQLKIEGVEHLPR---------------------RVTNEIASNSRYEVYTQGGIIFATSRILVVDFLTGRIPSDLITGILVYRAHRIIESCQEAFILRLFRQKNKRGFIKAFTDNAVAFDTGFCHVERVMRNLFVRKLYLWPRFHVAVNSFLEQH----KPEVVEIHVSMTPAMLAIQTAILDILNACLKELKCHNPSLEVEDLSLENALGKPFDKTIRHYLDPLWHQLGAKTKSLVQDLKILRTLLQYLSQYDCVTFLNLLESLRATEK----VFGQNSGWLFLDASTSMFVNARARVYRVPDVKLNKKAKTSEKTSSPEVQETKKELVLESNPKWEALTDVL-KEIEAENKESEALGGPGRVLICASDDRTCCQLRDYLSAGAETFLLRLYRKTFEKDGKAEEVWVNVRKGDGPKRTTKSDKRPKAAPNKERASAKRGAPLKRKKQELTLTQVLGSAEEPPEDKALEEDLCRQTSSS-------PEGCGVEI----------KRESFDLNVSSDAAYGILKEPLTIIHPLLG-CSDPYALTRVLHEVEPRYVVLYDAELTFVRQLEIYRASR---PGKPLRVYFLIYGGSTEEQRYLTALRKEKEAFEKLIREKASMVVPEEREGRDETNLDLAR--GSAALDAPTDTRKAGGQE--QNGTQSSIVVDMREFRSELPSLIHRRGIDIEPVTLEVGDYILTPELCVERKSVSDLIGSLHSGRLYSQCLAMSRYYRRPVLLIEFDPSKPFSLAPRGAFFQEMSSS--------------DVSSKLTLLTLHFPRLRLLWCPSPHATAELFEELKQNKPQPDAATAMAITADSE------TLPE-SDRYNPGPQDFVLKMPGVNAKNCRSLMNQVKNIAELATLSLERLTTILGHSGNAKQLHDFLHTAYADLVSKGRVRK-----------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q92889-1", "uniprot_id": "XPF_HUMAN", "id": "Q92889-1", "name": "DNA repair endonuclease XPF", "aln": "---------------------------------------------MESGQPARRIAMAP--------------------------------LLEYERQLVLELLDTDGLVVCARGLGADRLLYHFLQLHCHPA--------CLVLVLNTQPAEEEYFINQLKIEGVEHLPR---------------------RVTNEITSNSRYEVYTQGGVIFATSRILVVDFLTDRIPSDLITGILVYRAHRIIESCQEAFILRLFRQKNKRGFIKAFTDNAVAFDTGFCHVERVMRNLFVRKLYLWPRFHVAVNSFLEQH----KPEVVEIHVSMTPTMLAIQTAILDILNACLKELKCHNPSLEVEDLSLENAIGKPFDKTIRHYLDPLWHQLGAKTKSLVQDLKILRTLLQYLSQYDCVTFLNLLESLRATEK----AFGQNSGWLFLDSSTSMFINARARVYHLPDAKMSKKEKISEKMEIKEGEETKKELVLESNPKWEALTEVL-KEIEAENKESEALGGPGQVLICASDDRTCSQLRDYITLGAEAFLLRLYRKTFEKDSKAEEVWMKFRKEDSSKRIRKSHKRPKDPQNKERASTKERTLKK-KKRKLTLTQMVGKPEELEEEGDVEEGYRREISSS-------PESCPEEI----------KHEEFDVNLSSDAAFGILKEPLTIIHPLLG-CSDPYALTRVLHEVEPRYVVLYDAELTFVRQLEIYRASR---PGKPLRVYFLIYGGSTEEQRYLTALRKEKEAFEKLIREKASMVVPEEREGRDETNLDLVR--GTASADVSTDTRKAGGQE--QNGTQQSIVVDMREFRSELPSLIHRRGIDIEPVTLEVGDYILTPEMCVERKSISDLIGSLNNGRLYSQCISMSRYYKRPVLLIEFDPSKPFSLTSRGALFQEISSN--------------DISSKLTLLTLHFPRLRILWCPSPHATAELFEELKQSKPQPDAATALAITADSE------TLPE-SEKYNPGPQDFLLKMPGVNAKNCRSLMHHVKNIAELAALSQDELTSILGNAANAKQLYDFIHTSFAEVVSKGKGKK-----------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AB32U361-1", "uniprot_id": "A0AB32U361_DANRE", "id": "A0AB32U361-1", "name": "DNA repair endonuclease XPF", "aln": "-------------------------------------------------------MASA--------------------------------LLEYETEMFLSVFSTDGLLITAEGLGIDRLLLHFMKVYSEEG--------SLVLLLNTSTPEQEYLTERLRAEGVTHLPQ---------------------TVTSDVQSADRYNVYTKGGVLFVTSRILVVDFLTDRIPAHLVTGILVYRAHNIIESCQEAFILRLYRQKNKTGFIKAFTDKATSFSSGFCKVERVMRNLFVKKLFLWPRFQASVNATLDKH----KPDVVELHVTLTPAMRAIQSSILDIMNACLKELKRYNPTLEAEDLSLENSLGTAFEKTIRHYLDPLWHQLGSRTKSLVQDLKILRTLLLYLTQYDCVTFLNLLESLRTSQK----SFGSNSGWLFLDSSMSMFVNARSRVYRIQESK--KKLKVGETEQKQNLAPPKRELVLEKNPKWEALTEVL-QEIEKENSKSEHE--PGRVLICASDDRTCAQLKEYIQKGPEHLLNRLYSRTIGKE-DPQPDLLKLDKGWQKKDSARS-KGKNSRQKRTKANSKK-------------PAKMEKLSRVSQDDSADKDLN-ENSED-------EGGLIEEE----------EEEEIVLDLSSDDYYGILKEPLTVIHPLKG-CSDPYSLTRVLHEVDPMFVVLYDAELSFVRQLEIYKACR---PGKPLRVYFLIYGGSTEEQRYLTALNKEKQAFEHLIREKASMVVPEEREGREDTNLDLVR--SQEPASAATNTRKAGGLE--EVKEPHRIIVDMREFRSELPSLLHRRGLDIEPVTLEVGDYILTSDICVERKSVSDLIGSLQSGRLYTQCLSMTRFYRRPVLLIEFDPAKPFSLVARSDFRQEISAN--------------DVTSKLTLLTLHFPRLRLLWCPSPYVTAELFQELKHGRTEPDASTAQAVTAESE------TVTESADLYNPGPYDFLLRMPGVNVKNVKSLIKHVSCLADLVTFSQETLSEILGSSSNARMLYEFIHNP-MDVRPIQKNK------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q24087-1", "uniprot_id": "XPF_DROME", "id": "Q24087-1", "name": "DNA repair endonuclease XPF", "aln": "---------------------------------MADSCAENAAKGTENERPKEVEASADTVPQVEEGVEEYLKRKNMV-------------LLDYEKQMFLDLVEADGLLVCAKGLSYDRVVISILKAYSDSG--------NLVLVINSSDWEEQYYKSKIEPKYVHEVAS---------------------TAT------ERERVYLEGGLQFISTRILVVDLLKQRIPIELISGIIVLRAHTIIESCQEAFALRLFRQKNKTGFVKAFSSSPEAFTIGYSHVERTMRNLFVKHLYIWPRFHESVRTVLQPW----KIQSIEMHVPISQNITSIQSHILEIMNFLVQEIKRINRTVDMEAVTVENCVTKSFHKILQAQLDCIWHQLNSQTKLIVADLKILRSLMISTMYHDAVSAYAFMKRYRSTEY----ALS-NSGWTLLDAAEQIFKLSRQRVFNG-----------------------QQEFEPEPCPKWQTLTDLLTKEIPGDMRRSRRSEQQPKVLILCQDARTCHQLKQYLTQGGPRFLL---QQALQHEVPVGKLSDNYAKESQTRSAPPKNVSSNKELRREEVSGSQPPLAGMDELAQLLSESETEGQHFEESYMLTMTQPVEVGPAAIDIKPDPDVSIFET----------IPELEQFDVTAALAS-VPHQPYICLQTFKTEREGSMALEHMLEQLQPHYVVMYNMNVTAIRQLEVFEARRRLPPADRMKVYFLIHARTVEEQAYLTSLRREKAAFEFIIDTKSKMVIPKYQDGKTDEAFLLLKTYDDEPTDENAKSRQAGGQAPQATKETPKVIVDMREFRSDLPCLIHKRGLEVLPLTITIGDYILTPDICVERKSISDLIGSLNSGRLYNQCVQMQRHYAKPILLIEFDQNKPFHLQGKFMLSQQTSMAN------------ADIVQKLQLLTLHFPKLRLIWSPSPYATAQLFEELKLGKPEPDPQTAAALGSDEP------TAGE-QLHFNSGIYDFLLRLPGVHTRNIHGLLRKGGSLRQLLLRSQKELEELLQSQESAKLLYDILHVAHLPEKDEVTGSTALLAASKQFGAGSHNRFRMAAAASRRGRR", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P06777-1", "uniprot_id": "RAD1_YEAST", "id": "P06777-1", "name": "DNA repair protein RAD1", "aln": "MSQLFYQGDSDDELQEELTRQTTQASQSSKIKNEDEPDDSNHLNEVENEDSKVLDDDAVLYPLIPNEPDDIETSKPNINDIRPVDIQLTLPLPFQQKVVENSLITEDALIIMGKGLGLLDIVANLLHVLATPTSINGQLKRALVLVLNAKPIDNVRIKEALEELSWFSNTGKDDDDTAVESDDELFERPFNVVTADSLSIEKRRKLYISGGILSITSRILIVDLLSGIVHPNRVTGMLVLNADSLRHNSNESFILEIYRSKNTWGFIKAFSEAPETFVMEFSPLRTKMKELRLKNVLLWPRFRVEVSSCLNATNKTSHNKVIEVKVSLTNSMSQIQFGLMECLKKCIAELSRKNPELALDWWNMENVLDINFIRSIDSVMVPNWHRISYESKQLVKDIRFLRHLLKMLVTSDAVDFFGEIQLSLDANKPSVSRKYSESPWLLVDEAQLVISYAKKRIFYKNEYTLEENPKWEQLIHILHDISHERMTNHLQGPTLVACSDNLTCLELAKVLNASNKKRGVRQVLLNKLKWYRKQREETKKLVKEVQSQDTFPENATLNVSSTFSKEQVTTKRRRTRGASQVAAVEKLRNAGTNVDMEVVFEDHKLSEEIKKGSGDDLDDGQEENAANDSKIFEIQEQENEILIDDGDAEFDNGELEYVGDLPQHITTHFNKDLWAEHCNEYEYVDRQDEILISTFKSLNDNCSLQEMMPSYIIMFEPDISFIRQIEVYKAIVK---DLQPKVYFMYYGESIEEQSHLTAIKREKDAFTKLIRENANLSHHFETNEDLSHYKNLAERKLKLSKLRKSNTRNAGGQQGFHNLTQDVVIVDTREFNASLPGLLYRYGIRVIPCMLTVGDYVITPDICLERKSISDLIGSLQNNRLANQCKKMLKYYAYPTLLIEFDEGQSFSLEPFSERRNYKNKDISTVHPISSKLSQDEIQLKLAKLVLRFPTLKIIWSSSPLQTVNIILELKLGREQPDPSNAVILGTNKVRSDFNSTAKGLKDGDNESKFKRLLNVPGVSKIDYFNLRKKIKSFNKLQKLSWNEINELINDEDLTDRIYYFLRTEKEEQEQESTDENLESPGKTTDDNALHDHHNDVPEAPV----", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : * : .:. *.*:: ..**. :: ::: . ***::*:. :: . :. . .: .* .:* .**: ::***:**:*. : . ::*::* .*. : ...:*:* *.::*.**. **:***:. . :* :. :. *::* :::: :****: * : *: : . :*::*.:: : ** ::: :: : *:. * : : .:** : * : : : **::. .:* :* *:::** *: *.* :: :: :* * ::* : :: :: *:: :: *. : :: * . .: : :: . * .: . : : . . : . . . :. : : .: : . : . *.:: * :::::: ::: :**:*::.* :***: :. : *** :**::.:** ** :* ::.: : . * . . :.:*:*** ::** ***.:.** *::: *: : * : :***::*.::*:****:*******:..** .** * :.* * ****** :.* * : . :: ** *.*:** *:::*..** *.::: *** .: :**. .* : ::. * * . . :*.:*** : .* .: : .* * . : :: : :: ::: ", "identical_positions": 159, "similar_positions": 273, "identity": "14.36%" }, { "cls_id": "homologset.agr.MGI:1354164", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q99M31-1", "uniprot_id": "HSP7E_MOUSE", "id": "Q99M31-1", "name": "Heat shock 70 kDa protein 14", "aln": "--MAAIGVHLGCTSACVAVYK-DGRADVVANDAGDRVTPAIVAYS-EREQVVGLAAKQSRIRHVSSTVVKVKQILG--RSSADPQAQKYISESKCLVIEKNGKLRYEIDTGEETK----------LVNPEDVARLIFSKMKETAHSVLG-SDANDVVVTVPFDFGEKQKSALGEAAGAAGFNVLRLIHEPSAALLAYGIGQDHPTGKSNVLVFKLGGTSLSLSVMEVNSGMYRVLSTNTSDNIGGAHFTDTLAQYLASEFQRLFKHDVRGNARAMMKLMNSAEVAKHSLSTLGSANCFVDSLYEGQDFDCNVSRARFELLCSPLFNKCTEAIRELLRQTGFTAD---DINKVVLCGGSSRIPKLQQLIKDLFPA-VDLLN------SIPPDEVIPIGAAIEAGILVGKESTS-GDDSVMIECSAKDILVKGVDESGADRFTVLFPSGTPLPARRQHTLQAPG------------RVSSVCLELYESEGKNSAKEEAKFAQVVLQDLDKKENGLRDILAVLTMKRDGSLQVTCTDQDTGKCEAITVEVAS--------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6AYB4-1", "uniprot_id": "HSP7E_RAT", "id": "Q6AYB4-1", "name": "Heat shock 70 kDa protein 14", "aln": "--MAAIGVHLGCTSACVAVYK-DGRADVVANDAGDRVTPAVVAYS-EREQVVGLAAKQSRIRNISSTVVKVKQILG--RSTADPQAQKYISESKCLVIEKNGKLQYEIDTGEETK----------LVSPEDVARLIFSKMKETAHSVLG-SDANDVVVTVPFDFGEKQKSALGEAAGAAGFNVLRLIHEPSAALLAYGIGQDCPTGKSNVLVFKLGGTSLSLSIMEVNSGMYRVLSTNTSDNIGGVHFTDSLAQYLASEFQRLFKHDVRGSARAMMKLMNSAEVAKHSLSTLGSANCFVDSLYEGQDFDCNVSRARFELLCSPLFNKCIEAVRALLQQSGFTAD---DINKVVLCGGSSRIPRLQQLIKDLFPA-GDLLN------SIPPDEVIPIGAAIEAGILVGKESTS-GDDSVLIECSARDILVKGVDESGANRFTVLFPSGTPLPARRQHTLQAPG------------SISSVCLELYESEGKNSVKEETKFAQVVLQDLDKKENGLRDILAVLTMKRDGSLQVTCTDQETGKCEAITVEVAS--------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q0VDF9-1", "uniprot_id": "HSP7E_HUMAN", "id": "Q0VDF9-1", "name": "Heat shock 70 kDa protein 14", "aln": "--MAAIGVHLGCTSACVAVYK-DGRAGVVANDAGDRVTPAVVAYS-ENEEIVGLAAKQSRIRNISNTVMKVKQILG--RSSSDPQAQKYIAESKCLVIEKNGKLRYEIDTGEETK----------FVNPEDVARLIFSKMKETAHSVLG-SDANDVVITVPFDFGEKQKNALGEAARAAGFNVLRLIHEPSAALLAYGIGQDSPTGKSNILVFKLGGTSLSLSVMEVNSGIYRVLSTNTDDNIGGAHFTETLAQYLASEFQRSFKHDVRGNARAMMKLTNSAEVAKHSLSTLGSANCFLDSLYEGQDFDCNVSRARFELLCSPLFNKCIEAIRGLLDQNGFTAD---DINKVVLCGGSSRIPKLQQLIKDLFPA-VELLN------SIPPDEVIPIGAAIEAGILIGKENLL-VEDSLMIECSARDILVKGVDESGASRFTVLFPSGTPLPARRQHTLQAPG------------SISSVCLELYESDGKNSAKEETKFAQVVLQDLDKKENGLRDILAVLTMKRDGSLHVTCTDQETGKCEAISIEIAS--------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q5RGE6-1", "uniprot_id": "HSP7E_DANRE", "id": "Q5RGE6-1", "name": "Heat shock 70 kDa protein 14", "aln": "--MAAIGVHFGYTCACVAVFK-DGRADVVANDAGDRVTPAVVAYR-DTEQIVGIAAKQGRIRNAANTVVKVKQILG--RRYDDPDAQAHKEESKCIVVNKSGLPRYEIDTGETTK----------YVSPEDVAKLIFHKMKETAQSALG-SDVKDAVITVPFEFDEMQKNALRQAAESAGFNVLRLIHEPSAALLAYDIGQDSPLGKSHVLVYKLGGTSLSVTVLEVNSGVYRVLATQTDHQTGGESFTQELAQHLAAEFKKTFKQDVSGNARAMMKLMNSADVAKHTLSTLGSANCFVDSLYDGMDFECNVSRARFELICSSLFNKCIQPIKSLLEQVNLSTS---DVNKVVLSGGSARIPKLQQMIRDLFPD-VELLN------SIPPDEVIPVGAAMQAGILVGKDSLALGEDSITVDCCASDITLKEVDDSGLEVFTVLFPSGTPLPARRQHTLQGPG------------SLSSVRLQLFQAQQP--------IAQIVLGDLEPKEE-LHDVVTVLTMKRDGSLHVTCTEQSSGRSEAITIETAAAAS-----", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P38788-1", "uniprot_id": "SSZ1_YEAST", "id": "P38788-1", "name": "Ribosome-associated complex subunit SSZ1", "aln": "MSSPVIGITFGNTSSSIAYINPKNDVDVIANPDGERAIPSALSYV-GEDEYHGGQALQQLIRNPKNTIINFRDFIG--LPFDKCDVSKCANGAPAVEVDGKVGFVISRGEGKEEK----------LTVDEVVSRHLN-RLKLAAEDYIG-SAVKEAVLTVPTNFSEEQKTALKASAAKIGLQIVQFINEPSAALLAH-AEQFPFEKDVNVVVADFGGIRSDAAVIAVRNGIFTILATAHDLSLGGDNLDTELVEYFASEFQKKYQANPRKNARSLAKLKANSSITKKTLSNATSATISIDSLADGFDYHASINRMRYELVANKVFAQFSSFVDSVIAKAELDPL---DIDAVLLTGGVSFTPKLTTNLEYTLPESVEILGPQNKNASNNPNELAASGAALQARLISDYDADELAEALQPVIVNTPHLKKPIGLIGAKGEFHPVLLAETSFPVQKKLTLKQAKGDFLIGVYEGDHHIEEKTLEPIPKEENAEEDDESEWSDDEPEVVREKLYTLGTKLMELGIKNANGVEIIFNINKDGALRVTARDLKTGNAVKGEL", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "Q9VSI1-1", "uniprot_id": "Q9VSI1_DROME", "id": "Q9VSI1-1", "name": "", "aln": "-MWPRFGIKIGNSTLCIAHVRADGKAEVIANKQGDRVSQACLLWDGASEIECGLTAKQKMANRPRQAVAHSFQLLQPKEELTEEKLSSALREIPCDFDKEELVFRMEHTVPSDREDQDDRVVTKDLSAYQVTVELLRAELELAHQYHTDGEQAPIAVLSIPSYYPASAYKLLADAAQTAGFHVAQIITEPTAAVLGYSIGEEQTEQRRHVLTIKCGGLYSDIAFYSVQNGLFVQLATFGPFPIGGRQFTEALVQFICEEFRRKYKLDPHESRRSVAKIRTAAANCKHILTTMPSTQLYIDSLMDGVDYNAQMSRARFESLIQPVINNLIQQLGECVEQAQKEHPGLSKIDDIVLLGATMQIPKLQAAVGARFPD-AKLHN------SHSADEVVAIGCARQAVCLIDPLEQQLHKEEDCVVAEDDLFIWHGNDES---NAKLVLGRGSVLPAKIRISLPQSE----------------------------EGKGDDVSKAAASFKLRTGESEILARLPDSTIPEDGLYQLEVEVDVDDKDGNVVPLVRLRCM-----", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . :*: :* : .:* . .. . *:** *:*. : : : : * * * .. .:: : ::: . . . . . . . . : : . . : .:: : . . . . .*:::* : . * :* *::: ::* **:**:*.: : :::. . ** . :. *..*:: *:* ** : *.:.:. **:: :: : . *:: *: : *: *:. *: :*** :* *:...:.* *:* : . :: : . : : : .:: ::* *. *:* : :* .: . * .:*: . *.* :* : . . : : . :: : :*.: : :* . : : : : . . .: : . ", "identical_positions": 58, "similar_positions": 159, "identity": "10.41%" }, { "cls_id": "homologset.agr.MGI:1354165", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8C1A5-1", "uniprot_id": "THOP1_MOUSE", "id": "Q8C1A5-1", "name": "Thimet oligopeptidase", "aln": "-------------MKPPAACAGDVVDAAS----PASTVNHLRWDLSAQQIRALTTQLIEQTKCVYDRVGAQNFEDVSYESTLKALADVEVTYTVQRNILDFPQHVSPCKDIRAASTEADKKLSEFDVEMSMRQDVYQR--VVWLQEKTPKNSLKPEAARYLERLIKLGRRNGLHLPQDTQEKIKNIKKRLSLLCIDFNKNLNEDTTFLPFTREELGGLPEDFLSSLEKAEDGK------LKVTLKYPHYFPLLKKCHVPETRRLLEEAFNCRCKEENCAILKELVSLRAQKSSLLGFHTHADYVLEMNMAKTSQTVATFLDELAQKLKPLGEQERAVILELKEAECAKRGLPFDGRIHAWDMRYYMNQVEETRYRVDQNLLKEYFPMQVVTRGLLAIYQELLGLTFTLEEG---AAAWHEDVRLYSVR---DAASGEEIGKFYLDLYPREGKYGHAACFGLQPGCLRQDGSRQLAVAAMVANFTKPTPDAPSLLQHDEVETYFHEFGHVMHQLCSQAEFAMFSG-THVERDFVEAPSQMLENWVWEKEPLMRMSQHYRTGSEAPQDLLEKLIKSRQANAGLFNLRQIVLAKVDQVLHTQTDAD---PAEEYARLCQEILGVPATPGTNMP--ATFGHLAGG-YDAQYYGYLWSEVYSMDMFHTRFKQEGVLSPKVGMDYRTSILRPGGSEDASAMLKQFLGRDPKQDAFLLSKGLQVEGSE--APAC", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P24155-1", "uniprot_id": "THOP1_RAT", "id": "P24155-1", "name": "Thimet oligopeptidase", "aln": "-------------MKPPAACAGDVVDTVS----PCSTVNHLRWDLSAQQIRALTTQLIEQTKCVYDRVGAQDFEDVSYESTLKALADVEVTYTVQRNILDFPQHVSPNKDIRAASTEADKKLSEFDVEMSMRQDVYQR--VVWLQEKIPKDSLKPEAARYLERLIKLGRRNGLHLPQDTQEKIKNIKKRLSLLCIDFNKNLNEDTTFLPFTREELGGLPEDFLNSLEKTEDGK------LKVTLKYPHYFPLLKKCHVPETRRLLEEAFNCRCKEENCAILKELVSLRAQKSNLLGFRTHADYVLEMNMAKTSQTVATFLDELARKLKPLGEQERAVILELKEAECAKRGLPFDGRIHAWDMRYYMNQVEETRYRVDQNLLKEYFPMQVVTRGLLAIYQELLGLTFTLEEG---AAAWHEDVRLYSVR---DAASGEEIGKFYLDLYPREGKYGHAACFGLQPGCLRQDGSRQLAIAAMVANFTKPTPDVPSLLQHDEVETYFHEFGHVMHQLCSQAEFAMFSG-THVERDFVEAPSQMLENWVWEKEPLMRMSQHYRTGGEAPEDLLEKLIKSRQANAGLFNLRQIVLAKVDQVLHTQTDVD---PAEEYARLCQEILGVPATPGTNMP--ATFGHLAGG-YDAQYYGYLWSEVYSMDMFHTRFKQEGVLSPKVGMDYRTSILRPGGSEDASTMLKQFLGRDPKQDAFLLSKGLQVEGCE--PPAC", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P52888-1", "uniprot_id": "THOP1_HUMAN", "id": "P52888-1", "name": "Thimet oligopeptidase", "aln": "-------------MKPPAACAGDMADAAS----PCSVVNDLRWDLSAQQIEERTRELIEQTKRVYDQVGTQEFEDVSYESTLKALADVEVTYTVQRNILDFPQHVSPSKDIRTASTEADKKLSEFDVEMSMREDVYQR--IVWLQEKVQKDSLRPEAARYLERLIKLGRRNGLHLPRETQENIKRIKKKLSLLCIDFNKNLNEDTTFLPFTLQELGGLPEDFLNSLEKMEDGK------LKVTLKYPHYFPLLKKCHVPETRRKVEEAFNCRCKEENCAILKELVTLRAQKSRLLGFHTHADYVLEMNMAKTSQTVATFLDELAQKLKPLGEQERAVILELKRAECERRGLPFDGRIRAWDMRYYMNQVEETRYCVDQNLLKEYFPVQVVTHGLLGIYQELLGLAFHHEEG---ASAWHEDVRLYTAR---DAASGEVVGKFYLDLYPREGKYGHAACFGLQPGCLRQDGSRQIAIAAMVANFTKPTADAPSLLQHDEVETYFHEFGHVMHQLCSQAEFAMFSG-THVERDFVEAPSQMLENWVWEQEPLLRMSRHYRTGSAVPRELLEKLIESRQANTGLFNLRQIVLAKVDQALHTQTDAD---PAEEYARLCQEILGVPATPGTNMP--ATFGHLAGG-YDAQYYGYLWSEVYSMDMFHTRFKQEGVLNSKVGMDYRSCILRPGGSEDASAMLRRFLGRDPKQDAFLLSKGLQVGGCEPEPQVC", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P25375-1", "uniprot_id": "PRTD_YEAST", "id": "P25375-1", "name": "Saccharolysin", "aln": "MRLLLCKNWFASPVISPLLYTRSLYSMANTTSFPIAPQAPPNWSFTPSDISGKTNEIINNSNNFYDSMSKVESPSVS--NFVEPFMKFENELGPIINQLTFLQHVSSDKEIRDASVNSSMKLDELNIDLSLRHDIFLQFARVWQDVQSKADSVERETFKYVEKSYKDYIHSGLELDEGNRLKIKEIKKKISVNSINFSKNLGEQKEYITFTKEQLEGVPDSILTQFETIKSDKDSNETLYKVTFKYPDIFPVMKLASSAQTRKQAFLADQNKVPE-NEAILLDTLKLRDELASLLGYDTYANYNLYDKMAEDSTTVMNFLNDLKDKLIPLGRKELQVLQDMKAEDVKKLNQGADPNYYIWDHRYYDNKYLLENFNVDLEKISEYFPLEATITGMLEIYETLFNLKFIETKDSQNKSVWHDDVKQIAVWNMDDPKSPNFVGWIYFDLHPRDGKYGHAANFGLSSSFMIDDTTRSYPVTALVCNFSKSTKDKPSLLKHNEIVTFFHELGHGIHDLVGQNKESRFNGPGSVPWDFVEAPSQMLEFWTWNKNELINLSSHYKTGEKIPESLINSLIKTKHVNGALFTLRQLHFGLFDMKVHTCKDLQNLSICDTWNQLRQDIS-LISNGGTLSKGYDSFGHIMSDSYSAGYYGYLWAEVFATDMYHTKFAKD-PLNAKNGIQYRDIVLARGGLYDINDNLKEFLGREPSKDAFLKELGLQN----------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus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identical_positions": 248, "similar_positions": 238, "identity": "34.11%" }, { "cls_id": "homologset.agr.MGI:1354168", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P41034-1", "uniprot_id": "TTPA_RAT", "id": "P41034-1", "name": "Alpha-tocopherol transfer protein", "aln": "MAEMRPGPVVG-KQLNEQPDHSPLVQPGLAELRRRAQEEGVPETPQPLTDAFLLRFLRARDFDLDLAWRLMKNYYKWRAECPELSADLHPRSILGLLKAGYHGVLRSRDPTGSRVLIYRISYWDPKVFTAYDVFRVSLITSELIVQEVETQRNGVKAIFDLEGWQISHAFQITPSVAKKIAAVVTDSFPLKVRGIHLINEPVIFHAVFSMIKPFLTEKIKGRIHLHGNNYKSSLLQHFP-DILPLEYGGNESSMEDICQEWTNFIMKSEDYLSSISETIQ---------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8BWP5-1", "uniprot_id": "TTPA_MOUSE", "id": "Q8BWP5-1", "name": "Alpha-tocopherol transfer protein", "aln": "MAEMRPGPLVG-KQLNELPDHSPLLQPGLAELRRRVQEAGVPQTPQPLTDAFLLRFLRARDFDLDLAWRLMKNYYKWRAECPELSADLRPRSILGLLKAGYHGVLRSRDSTGSRVLIYRIAYWDPKVFTAYDVFRVSLITSELIVQEVETQRNGVKAIFDLEGWQVSHAFQITPSVAKKIAAVLTDSFPLKVRGIHLINEPVIFHAVFSMIKPFLTEKIKDRIHLHGNNYKSSMLQHFP-DILPREYGGKEFSMEDICQEWTNFIMKSEDYLSSISETIQ---------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P49638-1", "uniprot_id": "TTPA_HUMAN", "id": "P49638-1", "name": "Alpha-tocopherol transfer protein", "aln": "MAEARSQPSAG-PQLNALPDHSPLLQPGLAALRRRAREAGVPLAPLPLTDSFLLRFLRARDFDLDLAWRLLKNYYKWRAECPEISADLHPRSIIGLLKAGYHGVLRSRDPTGSKVLIYRIAHWDPKVFTAYDVFRVSLITSELIVQEVETQRNGIKAIFDLEGWQFSHAFQITPSVAKKIAAVLTDSFPLKVRGIHLINEPVIFHAVFSMIKPFLTEKIKERIHMHGNNYKQSLLQHFP-DILPLEYGGEEFSMEDICQEWTNFIMKSEDYLSSISESIQ---------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "B0S5J5-1", "uniprot_id": "B0S5J5_DANRE", "id": "B0S5J5-1", "name": "Alpha-tocopherol transfer protein", "aln": "---MKSEEVDETEELNNLPVDSSRIAPYLSELKEKA-EAELRIRDLDLSKTFLIRFLQARDFDVALALKLLINYHKWRQECPEITADLRPSSVIGLLQNNYHGVLRSRDDAGSRVLIYRIGKWNPKEFTAYEVFRVSLITSELIVQEWETQRNGLKAIFDLQDWCFAHALQINPSLAKKISSVLTDSFPLKVRGIHLINEPIFFRPVFAMIRPFLPDKIKQRIHMHGCSYARSLCNYFPKAVLPPVYGGTGPSVDEVCQEWTEYIMQSEDYLHRLSVDLGGEGGHASQS", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :. :** * .*. : * *: *:.:. * : *:.:**:***:*****: ** :*: **:*** ****::***:* *::***: .********* :**:******. *:** ****:*************** ******:******:.* .:**:**.**:****::*:*****************::*:.**:**:***.:*** ***:** .* *: ::** :** *** *::::*****::**:***** :* : ", "identical_positions": 158, "similar_positions": 67, "identity": "54.67%" }, { "cls_id": "homologset.agr.MGI:1354170", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "F1MAS1-1", "uniprot_id": "F1MAS1_RAT", "id": "F1MAS1-1", "name": "", "aln": "MQPTATMATAAATT----ATVALTTSWDNATNRPTAEPDPILDNYVLLVVVMSLFVGGTLVVLSGVLLLCKRCWEVHQRFN------RAMEETEKTTTTYLDNGTHPIQDPDCRGEDPEGQ------DTETERFLATTSTGRRVSFNEAALFEQSRKAQDKGRRYTLTEGDFHHLKNARLTHLHLPP--LKIATIHECDSGEASAAATPHPHPASTPKDSLAIFQP-----PGKSLTGHSVGPSSALPGDPYS----SVDFSEISPSASSDSGEGTSLDAG---TRGTKAAGP------ETAPGEMGTGSSGAGTVLQFFTRLRRHASLDGASPYFKVKKWKLESSQRASSLDTRGSPKRHHFQRQRAASESMEQE-GDIPHADFIQYIASAGDSVAFPPPRP--FLASPTSPPPTLGRLEAAEAAGGGSPETPPEHGI-SLGPEHAQ---QQDPQQEQDAEHAQCSYRDLWSLRASLELHAATASDHSSSGNDRDSVRSGDSSGSGSGGGGAAPAFPPPP--------------------------ESPPALRPKDGE--ARRLLQMDSGYASIEGRGAGDEVSELPAPARSPPRSPRAWPRR------------------------------------------------------------------PRRDYSIDEKTDALFHEFLRHDPHFDDAP---RHRARAHPHTHARKQWQQRGRQHSDPGG-------ARVATPPGATRPTRAPLRRGDSVDCP-----PEGRAPPITGDDPSIP------VIEEEP---------------------------------GGGGSGCPGSGLCVEP----------------AGALLDKLAASLDERLFSPRLAEPVASSPVLIVAAAAPTSPDHSPA", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q66L44-1", "uniprot_id": "CBARP_MOUSE", "id": "Q66L44-1", "name": "Voltage-dependent calcium channel beta subunit-associated regulatory protein", "aln": "MQPTATMATAAATT----ATVALTTSWDNATSRPTAEPDPILDNYVLLVVVMSLFVGGTLVVLSGVLLLCKRCWEVHQRFN------RAMEEAEKTTTTYLDNGTHPIQDPDCRGEDPEGQ------DTETERFLATSSTGRRVSFNEAALFEQSRKAQDKGRRYTLTEGDFHHLKNARLTHLHLPP--LKIATIHECDSGEASAAAT--PHPATTSKDSLAIFQP-----PGKTLTGHSVGPSSALPGGPYN----SVDFSEISPSTSSDSGEGISLDAG---TRGAKAAGP------ETVPGEMGTGSSGSGTVLQFFTRLRRHASLDGASPYFKVKKWKLEPSQRASSLDTRGSPKRHHFQRQRAASESMEQE-GDVPHADFIQYIASAGDSVAFPPPRP--FLASPTSPPPTLGRLEAAEAAGGASPETPPEHGI-SLGPEHAQ---QQDPQQEQDAEHAQCSYRDLWSLRASLELHAATASDHSSSGNDRDSVRSGDSSGSGSGGGGAAPAFPPPP--------------------------ESPPALRPKDGE--ARRLLQMDSGYASIEGRGAGDEVSELPAPARSPPRSPRAWPRR------------------------------------------------------------------PRRDYSIDEKTDALFHEFLRHDPHFDDAP---RHRTRAHPHTHARKQWQQRGRQHSDPGG-------ARAATPPGVARPTRAPLRRGDSVDCP-----PEGRALPITGDDPSIP------VIEEEP---------------------------------GGGGGGCPGSGLCVEP----------------AGALLDKLAASLDERLFSPRLAEPVASSQVLIVAAAAPTSPDHSPA", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8N350-3", "uniprot_id": "CBARP_HUMAN", "id": "Q8N350-3", "name": "Voltage-dependent calcium channel beta subunit-associated regulatory protein", "aln": "MQPTATMATAATTTTTTTATVALTTSWDNATGRPTAEPDPILDNYVLLVVVMSLFVGGTLVVLSGVLLLCKRCWDVHQRLN------RAMEEAEKTTTTYLDNGTHPAQDPDFRGEDPECQ------DAETERFLSTSSTGRRVSFNEAALFEQSRKTQDKGRRYTLTEGDFHHLKNARLTHLHLPP--LKIVTIHECDSGEASSATT--PHPATSPKATLAIFQP-----PGKALTGRSVGPSSALPGDPYNSAAGATDFAEISPSASSDSGEGTSLDAG---TRSTKAGGPG----AAAGPGEAGPGS-GAGTVLQFLTRLRRHASLDGASPYFKVKKWKLEPSQRAASLDTRGSPKRHHFQRQRAASESTEQEEGDAPQEDFIQYIARAGDAVAFPHPRP--FLAS---PPPALGRLEAAEAAGGASPDSPPERGAGSAGPEQQQPPLEPDAERDAGPEQAQTSYRDLWSLRASLELHAA-ASDHSSSGNDRDSVRSGDSSGSGSGG--AAPAFPPP----------------------------SPPAPRPKDGE--ARRLLQMDSGYASIEGRGAGDDTEPPAAPAR--PRSPRAWPRR------------------------------------------------------------------PRRDYSIDEKTDALFHEFLRHDPHFDDTPAAARHRARAHP--HARKQWQ-RGRQHSDPGARAAPALAGTPAPPAGAARPARAPLRRGDSVDGP-----PDGRTLGGAGDDPAIP------VIEEEP---------------------------------GGGG--CPGSGLCVLP----------------SGSVLDKLAAGLDERLFPPRLAEPVVATPALV--AAAPTSPDHSPA", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8N7UUZ9-1", "uniprot_id": "A0A8N7UUZ9_DANRE", "id": "A0A8N7UUZ9-1", "name": "", "aln": "MSNDSAILTN-------------STAEPPTNGTLSSET---QNGYVLLLVLLSIFVGGTLVLLSVLLIVCRRCCEGDRRHAWFIVCLRASDDTEKSNTTYIEE-AQPVHEITIRVDESDCLSAASSHDMETERFLSTGTTGRRVSFNEAALFDHSKKTQEKGRRYTLTEGDFHHLKNARLTHLHLPPPALQILTIHECESSENSLAMM----TRPVAKSSLSIFQPPVCSLPQTALTSRTLSPSSALPGDTLN-STVDTTFCESITKAGAEPSSPCLLEVRGGVGRGADIMGNGREAASASATALSSSGGVSQGPMLQFFTKLRRHASLEGASPYFKIKKWKFDSSQRASSLDMRGSPKRRQFQRQRAASESMDQEEHDAHHIDLIQYIARTKDITYCPARASPRLLSPPSTPPPPLGRLEVEVMVEPSCSRALG-PGVIGLTSEPPDE--SLGMGFHQESLEPQTLYRDIWTLRASLERYVS--SDQSSN-NDRDSVRSDAESVCSLGGKYEMGGLPRYPSQDIGDEMEGDADLPLEESSEKGRKQDSVDSERGSDGEPGNRKLLQMDSGYASIEAPSRAPEELRLFGSSSSSSKDGSAMERRHFFSSGHKGTVCESFDTDILDEELEEEPTGASGGVDGVETSESTMLWSPYGQMFTQRDAQPHPPVLSRRDYSIDEKTEALFHEFLRHDPQFDQQE--SPLRSKHRSRVHLRKQWQ-RSKQYSDPGQR-FQTSFDRYRTPLRRGETVNYPLETSYQSTLPRIISAPDEESSEGATSTPEIPKGDQDATTDVDPDKTRISSSSESSGIIHKKEFLEASKPLPMTDIAGEQSVGRENSRQVLPPPDEPTPECTSYGPQTITEELSDKLAATLEERLYSD--LRRTRETPECSTVTMTHTSPDHSPV", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*. ::: * :*: :.. ::*. :.****:*::*:*******:** :*::*:** : .:* ** :::**:.***::: ::* :: * ::.: * ******:* :*************::*:*:*:*************************** *:* *****:*.* * * . . .* :*:**** * .:**.:::.*******.. . . *.* ..:.::... *:. *.:. * : .. ..*. . *.:***:*:*******:*******:****::.****:*** ******::********** :** * : *:***** : * . * . :*:. ***.*****. . ... : * . .* : . . . . ..* ***:*:****** :.: **:**. ********. .* .. ** .:* * : * .*** *:************. . . : ..: .:. * ** .**********:***********:**: *:: :. * ***** *.:*:**** .* .... **. . . * *: .: : . * ** . : :* * . .* : * : : ***** *:***:. . . : : : *******.", "identical_positions": 297, "similar_positions": 194, "identity": "32.75%" }, { "cls_id": "homologset.agr.MGI:1354171", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O35228-1", "uniprot_id": "IL27B_MOUSE", "id": "O35228-1", "name": "Interleukin-27 subunit beta", "aln": "MSKLLFLSLALWASRSPGY-TETALVALSQPRVQCHASRYPVAVDCSWTPLQAPNSTRSTSFIATYRLGVATQQQSQPCLQRSPQASRCTIPDVHLFSTVPYMLNVTAVHPGGASSSLLAFVAERIIKPDPPEGVRLR-TAGQRLQVLWHPPASWPFPDIFSLKYRLRYRRRGASHFRQVGPIEATTFTLRNSKPHAKYCIQVSAQDLTDYGKPSDWSLPGQVESAPHKP", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "M0RD76-1", "uniprot_id": "M0RD76_RAT", "id": "M0RD76-1", "name": "Interleukin-27 subunit beta", "aln": "MSKLLLLSLALWASCSPGN-TGTALVDLSQPRVRCHASRYPVAVDCSWMPLQAPNSTRAMSFIATYRLGVAAQQQSQPCLQRTPQASRCTIPHVHLFSTVPYLLNVTVVHPGGANSSLLAFVAERIIKPDPPEGVRLR-KAGQRLQVLWHPPASWPFPDIFSLKYRLRYRRRGASHFRQVGPIEATTFTLRNTQPHAKYCIQVSAQDLTDYGKPSDWSLPGQVERAPQKP", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q14213-1", "uniprot_id": "IL27B_HUMAN", "id": "Q14213-1", "name": "Interleukin-27 subunit beta", "aln": "MTPQLLLALVLWASCPPCSGRKGPPAALTLPRVQCRASRYPIAVDCSWTLPPAPNSTSPVSFIATYRLGMAARGHSWPCLQQTPTSTSCTITDVQLFSMAPYVLNVTAVHPWGSSSSFVPFITEHIIKPDPPEGVRLSPLAERQLQVQWEPPGSWPFPEIFSLKYWIRYKRQGAARFHRVGPIEATSFILRAVRPRARYYVQVAAQDLTDYGELSDWSLPATATMSLGK-", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*: *:*:*.**** .* . . *: ***:*:*****:****** ***** . *********:*:: :* ****::* :: ***..*:*** .**:****.*** *:.**::.*::*:************ * ::*** *.**.*****:****** :**:*:**::*::*******:* ** :*:*:* :**:********: ******. . : * ", "identical_positions": 133, "similar_positions": 56, "identity": "57.83%" }, { "cls_id": "homologset.agr.MGI:1354175", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O89049-1", "uniprot_id": "TRXR1_RAT", "id": "O89049-1", "name": "Thioredoxin reductase 1, cytoplasmic", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------MNDSKDAPKSYDFDLIIIGGGSGGLAAAKEAAKFDKKVMVLDFVTPTPLGTRWGLGGTCVNVGCIPKKLMHQAALLGQALKDSRNYGWKLEDTVKHDWEKMTESVQNHIGSLNWGYRVALREKKVVYENAYGKFIGPHKIMATNNKGKEKVYSAERFLIATGERPRYLGIPGDKEYCISSDDLFSLPYCPGKTLVVGASYVALECAGFLAGIGLDVTVMVRSILLRGFDQDMANKIGEHMEEHGIKFIRQFVPTKIEQIEAGTPGRLKVTAKSTNSEETIEDEFNTVLLAVGRDSCTRTIGLETVGVKINEKTGKIPVTDEEQTNVPYIYAIGDILEGKLELTPVAIQAGRLLAQRLYGGSTVKCDYDNVPTTVFTPLEYGCCGLSEEKAVEKFGEENIEVYHSFFWPLEWTVPSRDNNKCYAKVICNLKDNERVVGFHVLGPNAGEVTQGFAAALKCGLTKQQLDSTIGIHPVCAEIFTTLSVTKRSGGDILQSGCUG", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9JMH6-1", "uniprot_id": "TRXR1_MOUSE", "id": "Q9JMH6-1", "name": "Thioredoxin reductase 1, cytoplasmic", "aln": "MPVDDCWLYFPASRGRTFVQTVWVAPTCPNCCWFPGFLP--PVPRPPHVPRVLLRGPRGAVLPASRPSKTLPSSSQTPCP--TDP-----CICPP------PSTPDSRQEKNTQSELPNK------------------------KGQLQKLPTMNGSKDPPGSYDFDLIIIGGGSGGLAAAKEAAKFDKKVLVLDFVTPTPLGTRWGLGGTCVNVGCIPKKLMHQAALLGQALKDSRNYGWKVEDTVKHDWEKMTESVQSHIGSLNWGYRVALREKKVVYENAYGRFIGPHRIVATNNKGKEKIYSAERFLIATGERPRYLGIPGDKEYCISSDDLFSLPYCPGKTLVVGASYVALECAGFLAGIGLDVTVMVRSILLRGFDQDMANKIGEHMEEHGIKFIRQFVPTKIEQIEAGTPGRLRVTAQSTNSEETIEGEFNTVLLAVGRDSCTRTIGLETVGVKINEKTGKIPVTDEEQTNVPYIYAIGDILEGKLELTPVAIQAGRLLAQRLYGGSNVKCDYDNVPTTVFTPLEYGCCGLSEEKAVEKFGEENIEVYHSFFWPLEWTVPSRDNNKCYAKIICNLKDDERVVGFHVLGPNAGEVTQGFAAALKCGLTKQQLDSTIGIHPVCAEIFTTLSVTKRSGGDILQSGCUG", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q16881-1", "uniprot_id": "TRXR1_HUMAN", "id": "Q16881-1", "name": "Thioredoxin reductase 1, cytoplasmic", "aln": "MGCAEG--KAVAAAAPTELQTKGKNGDGRRRS-AKDHHPGKTLPENPAGFTSTATADSRALLQAYIDGHSVVIFSRSTCTRCTEVKKLFKSLCVPYFVLELDQTEDGRALEGTLSELAAETDLPVVFVKQRKIGGHGPTLKAYQEGRLQKLLKMNGPEDLPKSYDYDLIIIGGGSGGLAAAKEAAQYGKKVMVLDFVTPTPLGTRWGLGGTCVNVGCIPKKLMHQAALLGQALQDSRNYGWKVEETVKHDWDRMIEAVQNHIGSLNWGYRVALREKKVVYENAYGQFIGPHRIKATNNKGKEKIYSAERFLIATGERPRYLGIPGDKEYCISSDDLFSLPYCPGKTLVVGASYVALECAGFLAGIGLDVTVMVRSILLRGFDQDMANKIGEHMEEHGIKFIRQFVPIKVEQIEAGTPGRLRVVAQSTNSEEIIEGEYNTVMLAIGRDACTRKIGLETVGVKINEKTGKIPVTDEEQTNVPYIYAIGDILEDKVELTPVAIQAGRLLAQRLYAGSTVKCDYENVPTTVFTPLEYGACGLSEEKAVEKFGEENIEVYHSYFWPLEWTIPSRDNNKCYAKIICNTKDNERVVGFHVLGPNAGEVTQGFAAALKCGLTKKQLDSTIGIHPVCAEVFTTLSVTKRSGASILQAGCUG", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " **..:* * ***:*******************::.***:*****************************************:********:*:******::* *:**.*************************:*****:* *********:****************************************************************************************************** *:***********:*.*:****** **.*:***:**:***:***.**************************************.*:******************.**.*****:*************.**********************:*******:***********:*** **:******************************:**************:***********..***:****", "identical_positions": 449, "similar_positions": 43, "identity": "68.87%" }, { "cls_id": "homologset.agr.MGI:1354178", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9QXU7-1", "uniprot_id": "PROK2_MOUSE", "id": "Q9QXU7-1", "name": "Prokineticin-2", "aln": "MGDPRCAPLLLLLLLP-LLFTPPAGDAAVITGACDKDSQCGGGMCCAVSIWVKSIRICTPMGQVGDSCHPLTRKSHVANGRQERRRAKRRKRKKEVPFWGRRMHHTCPCLPGLACLRTSFNRFICLARK", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8R413-1", "uniprot_id": "PROK2_RAT", "id": "Q8R413-1", "name": "Prokineticin-2", "aln": "MEDPRCAPLLLLLLLP-LLLTPPAGDAAVITGACDKDSQCGGGMCCAVSIWVKSIRICTPMGQVGDSCHPLTRK---------------------VPFWGRRMHHTCPCLPGLACLRTSFNRFICLARK", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9HC23-1", "uniprot_id": "PROK2_HUMAN", "id": "Q9HC23-1", "name": "Prokineticin-2", "aln": "MRSLCCAPLLLLLLLPPLLLTPRAGDAAVITGACDKDSQCGGGMCCAVSIWVKSIRICTPMGKLGDSCHPLTRKNNFGNGRQERRKRKRSKRKKEVPFFGRRMHHTCPCLPGLACLRTSFNRFICLAQK", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* . *********** **:** ***************************************::********** ***:****************************:*", "identical_positions": 97, "similar_positions": 6, "identity": "75.19%" }, { "cls_id": "homologset.agr.MGI:1354184", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9JHI8-1", "uniprot_id": "NOX4_MOUSE", "id": "Q9JHI8-1", "name": "NADPH oxidase 4", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MAVSWRSWLANEG----------------VKHLCLLIWLSLNVLLFWKTFLLYNQGPEYYYIHQMLGLG----LCLSRASASVLNLNCSLILLPMCRTVLAYLRGSQKVPSRRTRRLLDKSKTLHITCGVTICIFSGVHVAAHLVNALNFSVNYSEDFLELNAARYQNEDPRKLLFTTIPGLTG----VCMVVVLFLMVTASTYAIRVSNYDIFWYTHNLFFVFYMLLLLH----------------------------------VSGGLLK--YQTNVDTHPPGCISLNQTSSQNMSIPDYVSEHFHGSLPRGFSKLEDRYQKTLVKI----------------CLEEPKFQAHFPQTWIWISGPLCLYCAERLYRCIR-----------------------------SNKPVTIISVINHPSDVMELRMIKENFKARP--------------GQYIILHCPSVSALEN-HPFTLTMCPTETKATFG-----VHFKVVG--DWTERFRDLLLPPSSQDSEILPFIHSRN------------------------------------------------------------------------------------------------------------------------------------YPKLYIDGPFGSPFEESLNYEVSLCVAGGIGVT-PFASILNTLLD-DWKP-------------------YKLRRLYFIWVCRDIQSFQWFADLLCVLHNKFWQE------------------NRPDFVNIQLYLSQTDGIQKIIGEKYHTLNSRLFIGRPRWKLLFDEIAKCNRGKTVGVFCCGPS-SISKTLHSLSNRNNSYGTKFEYNKESFS--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q924V1-1", "uniprot_id": "NOX4_RAT", "id": "Q924V1-1", "name": "NADPH oxidase 4", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MALSWRSWLANEG----------------VKHLCLLVWLSLNVLLFWKTFLLYNQGPEYYYIHQMLGLG----LCLSRASASVLNLNCSLILLPMCRTVLAYLRGSQKVPSRRTRRLLDKSKTLHITCGITICIFSGVHVAAHLVNALNFSVNYSEHFLALNAARYQNEDPRKLLFTTVPGLTG----VCMVVVLFLMVTASTYAIRVSNYDIFWYTHNLFFVFYMLLLLH----------------------------------VSGGLLK--YQTNLDTHPPGCISLNRTPSQNMSIADYVSEHFHGSLPGGFSKLEDHYQKTLVKI----------------CLEEPKFQAHFPQTWIWISGPLCLYCAERLYRCIR-----------------------------SNKPVTIISVINHPSDVMELRMIKENFKARP--------------GQYIILHCPSVSALEN-HPFTLTMCPTETKATFG-----VHFKVVG--DWTERFRDLLLPPSSQDSEILPFIQSRN------------------------------------------------------------------------------------------------------------------------------------YPKLYIDGPFGSPFEESLNYEVSLCVAGGIGVT-PFASILNTLLD-DWKP-------------------YKLRRLYFIWVCRDIQSFQWFADLLYVLHNKFWQE------------------NRPDFVNIQLYLSQTDGIQKIIGEKYHTLNSRLFIGRPRWKLLFDEIAKCNRGKTVGVFCCGPS-SISKTLHNLSNRNNSYGTKFEYNKESFS--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9NPH5-1", "uniprot_id": "NOX4_HUMAN", "id": "Q9NPH5-1", "name": "NADPH oxidase 4", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MAVSWRSWLANEG----------------VKHLCLFIWLSMNVLLFWKTFLLYNQGPEYHYLHQMLGLG----LCLSRASASVLNLNCSLILLPMCRTLLAYLRGSQKVPSRRTRRLLDKSRTFHITCGVTICIFSGVHVAAHLVNALNFSVNYSEDFVELNAARYRDEDPRKLLFTTVPGLTG----VCMVVVLFLMITASTYAIRVSNYDIFWYTHNLFFVFYMLLTLH----------------------------------VSGGLLK--YQTNLDTHPPGCISLNRTSSQNISLPEYFSEHFHEPFPEGFSKPAEFTQHKFVKI----------------CMEEPRFQANFPQTWLWISGPLCLYCAERLYRYIR-----------------------------SNKPVTIISVMSHPSDVMEIRMVKENFKARP--------------GQYITLHCPSVSALEN-HPFTLTMCPTETKATFG-----VHLKIVG--DWTERFRDLLLPPSSQDSEILPFIQSRN------------------------------------------------------------------------------------------------------------------------------------YPKLYIDGPFGSPFEESLNYEVSLCVAGGIGVT-PFASILNTLLD-DWKP-------------------YKLRRLYFIWVCRDIQSFRWFADLLCMLHNKFWQE------------------NRPDYVNIQLYLSQTDGIQKIIGEKYHALNSRLFIGRPRWKLLFDEIAKYNRGKTVGVFCCGPN-SLSKTLHKLSNQNNSYGTRFEYNKESFS--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A8DWJ8-1", "uniprot_id": "A8DWJ8_DROME", "id": "A8DWJ8-1", "name": "", "aln": "MNADQESNNHRGSVSSSRSLEIPATPSRSPKKVSFSDELPQSQTPAQQPINQQSAPTVVSHVLQQAAQYLERLHGARDSAEEKTEEVQPERADIRDSSDTSEAAVLDLDALDASADEPAANAGPIVASSPSILIGSVNRQEAIGSANGNGNANPNQRQSNLYMERYNLNLDKNCSSMELEARREKQRWLLISECSALFDEGEGKHTREAFRKLFLDEEFQQKLFQLFDLERNGYLLQDRWIEHLKGRLTDDRQMDFAEQIESVAYVICGENKRVSFKNFRDIWHTRGILDKLYRLIELDGSNLVSTNQVMEFISHLTNSRPRTGFDKSSLARLEQLFRTTVGNEQEIRREEFQKIVTSKNPFFTERVFQIFDKDNSGSISLQEFIDAIHQFSGQSADDKIRFLFKVYDIDGDGLIQHKELHDVIRHCIKENGMEFSEDQIEDLTSAMFEDADPHNSGEITYEALKNQLHKHGGLLENLSITIDRWLVPIAEDRQAGGAAKSGFWNSLPHQFSLAYMKNNQVFVTYLFFYITVNLCLFISRAIQYRASNGFVIIARACGQCLNFNCAWVLVLMLRHSLTYLRGR----GLSSYLPLDHHVYLHKLTGITISVLSLIHTIMHLFNFSIIVINDPNINAGHYTIGEWLLTDRPGLFGLIPGCANPTGVALLAILVVMFVCSQPFVRRKGSFEVFYWTHLLYVPFWILCLFHGPNFWKWFLLPGLVYIVERALRFIWMRGEHGKTYISSGLLLPSKVVHLVIKRPHHFNFRPGDYVFVNIPAIANYEWHPFTISSAPEQEDYMWLHIRTVGEWTNRLYRYFEREQQKLQQSGSSQEIPQHMHAIPTPSFMLLNEARNPAIAGERSATPQTDFLAKNLGVQAVPPVRPPRQNRKPAPGAPIDPPATGVNRIRSIKKTLQRTFSRKEAVDPKKGIPNGAFIADGEREDSNLKQ-RPLEKSISLPDISVKSKKRSRLKALRALGRSESESAFDEKRVRRARNNSVGLAYLSPQNKSLAQSFRYMRTKPTIIAFKTPSMEEREHQVAAGEANGASPASRAEQGQLSSRMDSADKLQLARLSLSAEGASKPLEDQTQTGSPSRKSILRRPTFLRSLSASINNRTGGGGGGSTGSSTTNSGGKVTLDAGVMEIFIDGPYGAPSSHIFGAQHAVLIGTGIGVT-PFASILQSIMHRYWKARHSCPRCQFEWASEIPKSVMNLRKVDFFWINRDQRSFEWFVNLLSQLEIEQAELGGAMERFLDMHMYITSALQRTDMKAVGLQLALDLLHEKGKRDLITGLKTRTNAGRPNWDKVFKQLQAQQKGK-VTVFYCGPP-QLAKTLRYKCDQYG-----FAFRKECF---", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q08908-1", "uniprot_id": "FRE5_YEAST", "id": "Q08908-1", "name": "Ferric reductase transmembrane component 5", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MLFARLVLLLVYLAPGSLAKPASTKKRTQWDQIAIDACAKELESHKFDTDVKGRHATLCTYEPALGSWLHCAKDVLDSRKKSKKIFEKTFSKINQYCHDYHKDEVVSNEEYYR-----------------------------------------------------------------IFANASLFIRPLDEVKEN-------------IRYPVTPNKASLDRWVWAYFGPLDNIDKGNVYGVTICLYWIG----VLFIAAVYHFLNFSR-LKQTVFKNKVSAFLRGHYVLPALVHNHAMSVGRWFFIGLVPTRLETLVLFGYVLLHGFLLSSYN--------FDHNELLSDRRSQVLIFLSDRAGILAFAHFPLIVLFGGKNSTMTWLTGIRYTAFITYHKWLGRFMLVDCT----------------------------------IHAIGYTYHAYIENYWKYVKYSDLWTSGRHAMIIVGILVFFSFFFFRRHYYELFVITHIILAIG----------------FFHACWKHCYKLGWGEWIMACALFWIADRILRLIK--------------------------IAIFGMPWAKLKLCGESMIEVRISKSSKWWKAEP--------------GQYIYLYFLRPKIFWQSHPFTVMDSLVEDGELVV------VITVKN--GLTKKLQEYLLESEGYT-----------------------------------------------------------------------------------------------------------------------------------------------EMRVLAEGPYGQSTRTHL-FESLLFIAGGAGVPGPLSMAIKAGRQVKSND--------------------SHQMIKFVWSVRNLDLLEVYRKEIMVLKELNIDTKIYFTG------------ERKDESNTEEGAIANMSTEGRLLTTSKSAEMITDFGRPNIDEIIEEAVSG--AKSLLVTCCGSEGFVDKTRELTAKRVLEHGDKWIEYVEEFQNW", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :: :. : . : . : : * **:. : . ::*** . :. :. * :. * . * * :: :.. :. . : :::.: .. . . : *: :. ::* : . . : .: : : . : : :. * : : * * . : . .: .: : * :* . : : :*: . : : . . : : : .: :**:* . : : : :. * **. *:: ::: . : . : : *.* *: :. : . : *. : :* * : : ***. . ::.: .* : * **. : ** . ..: : * * ", "identical_positions": 42, "similar_positions": 133, "identity": "3.1%" }, { "cls_id": "homologset.agr.MGI:1354367", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q5I0K8-1", "uniprot_id": "RT07_RAT", "id": "Q5I0K8-1", "name": "Small ribosomal subunit protein uS7m", "aln": "MAAPALRAARRWSGLALGVRCAVWNLPGITQVRWSRYAPEFRDPLIDKEHYRKQVSELTEEEKYDLELKKTQLIKAAAATETSSVFADPVISKFTNMMMKGGNKVLARSLMAQTLEAVKRK-------QFEKYRAASAEEQATIER------------NPYKIFHEALRNCEPVIGLVPILKG-GHFYQVPVPLADRRRRFLAMKWMITECRENKPRRMLMPEKLSHELLEAFHNRGPVIKRKHNMHKMAEANRALAHYRWW", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q80X85-1", "uniprot_id": "RT07_MOUSE", "id": "Q80X85-1", "name": "Small ribosomal subunit protein uS7m", "aln": "MAAPALRAPLRWSGLALGVRCAVWNLPGLTQVRGSRYAPEFREPLIDKEYYRKPVAELTEEEKYDQELKKTQFIKAAAATETSSVFADPVISKFTNMMMKGGNKVLARSLMAQTLEAVKRK-------QFEKYRAASAEEQATIER------------NPYRIFHEALKNCEPVIGLVPILKG-GHFYQVPVPLADRRRRFLAMKWMITECRENKPRRTLMPEKLSHELLEAFHNRGPVIKRKHNMHKMAEANRALAHYRWW", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9Y2R9-1", "uniprot_id": "RT07_HUMAN", "id": "Q9Y2R9-1", "name": "Small ribosomal subunit protein uS7m", "aln": "MAAPAVKVARGWSGLALGVRRAVLQLPGLTQVRWSRYSPEFKDPLIDKEYYRKPVEELTEEEKYVRELKKTQLIKAAPAGKTSSVFEDPVISKFTNMMMIGGNKVLARSLMIQTLEAVKRK-------QFEKYHAASAEEQATIER------------NPYTIFHQALKNCEPMIGLVPILKG-GRFYQVPVPLPDRRRRFLAMKWMITECRDKKHQRTLMPEKLSHKLLEAFHNQGPVIKRKHDLHKMAEANRALAHYRWW", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q498Z6-1", "uniprot_id": "RT07_DANRE", "id": "Q498Z6-1", "name": "Small ribosomal subunit protein uS7m", "aln": "MAASVRHLLKPWT-------------PSLCLMRWSRYNPYYLDPEPRKDAP-VSDSELSPEQKELQELKTVRPIKAALTGDTSSAFSDPLISKFINMMMYDGNKVLARGIMTQTLETIKRK-------QVEKYHKSPAAKREEIEC------------NPYAIFHQAMENCKPVIGLASIQKG-GKFYQVPVPLTDNRRRFMAMKWMITECRTNKQGRTLMYEKLSQELLAAFANEGNVIKRKHDLHKMAEANRAYAHYRWW", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VKX4-1", "uniprot_id": "RT07_DROME", "id": "Q9VKX4-1", "name": "Small ribosomal subunit protein uS7m", "aln": "MSLLGRIAEKTSR------------LSCLRLM--SVYPTHYVEPIVQKYKQLEQKNDLS-------KLYHVP-IKAAVNKSSDTIFHDDTKHKMINYITKKGNSALARTLLSKTLELIKRT-------QTEHMNLAKGEK-TTINT------------NPETLLKQAVENCRPLLQVTAIKRG-GVTYQVPVPITTKRSYFLAMKWLLEAARE-KERKVSLPEKLAWEILDAAHGQGRVIKRKDDLHRLCESNRAYAHYRWS", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P47150-1", "uniprot_id": "RT07_YEAST", "id": "P47150-1", "name": "Small ribosomal subunit protein uS7m", "aln": "MLHCARRYMLVRP-----------RLLWQSGTCVARFQSSVRTPASEPSAEKGVDEWLEAINELREEFSAKEYLPETSLAPPGQSKVDLLQGSQAGSKIKPTAEQLAQWEALKSVPIPPRKNATLDHITNMIMRHGKKEKAQTILSRALYLVYCQTRQDPIQALEKSLDELAPLMMTKTFNTGVAKASVIPVPLNKRQRNRIAWNWIVQSANQRVSSDFAV--RLGEELTAIAKGTSSAFEKRDQIHKTAIAHRAYIQLK--", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* : : . * * :: : : .. * . . . **: ::: *. . . : * :* :.::: : *:: .: * . :***: .: :* :*:: .. : :*. :: . . .::::.::*: . ::** : : ", "identical_positions": 20, "similar_positions": 63, "identity": "7.63%" }, { "cls_id": "homologset.agr.MGI:1354372", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "F8VQN3-1", "uniprot_id": "GPR31_MOUSE", "id": "F8VQN3-1", "name": "12-(S)-hydroxy-5,8,10,14-eicosatetraenoic acid receptor", "aln": "MERTNCSAASTVVETAVGTMLTLECVLGLMGNAVALWTFFYRLKVWKPYAVYLFNLVVADLLLATSLPFFAAFYLKGKTWKLGHMPCQVLLFLLAFSRGVGVAFLTTVALDRYLRVVHPRLRVNLLSLRAAWGISSLIWLLMVVLTPQNLLTCRTTQNSTECPSFYPTGGAKAIATCQEVLFFLQVLLPFGLISFCNSGLIRTLQKRLRESDKQPRIRRARVLVAIVLLLFGLCFLPSVLTRVLVHIFQEFKSCSVQQAIVRASDIAGSLTCLHSTLSPAIYCFSNPAFTHSYRKVLKSLRGRRKAAESPSDNLRDSYS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O00270-1", "uniprot_id": "GPR31_HUMAN", "id": "O00270-1", "name": "12-(S)-hydroxy-5,8,10,14-eicosatetraenoic acid receptor", "aln": "MPFPNCSAPSTVVATAVGVLLGLECGLGLLGNAVALWTFLFRVRVWKPYAVYLLNLALADLLLAACLPFLAAFYLSLQAWHLGRVGCWALHFLLDLSRSVGMAFLAAVALDRYLRVVHPRLKVNLLSPQAALGVSGLVWLLMVALTCPGLLISEAAQNSTRCHSFYSRADGSFSIIWQEALSCLQFVLPFGLIVFCNAGIIRALQKRLREPEKQPKLQRAQALVTLVVVLFALCFLPCFLARVLMHIFQNLGSCRALCAVAHTSDVTGSLTYLHSVLNPVVYCFSSPTFRSSYRRVFHTLRGKGQAAEPPDFNPRDSYS", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* .****.**** ****.:* *** ***:*********::*::*********:**.:******:.***:*****. ::*:**:: * .* *** :**.**:***::**************:***** :** *:*.*:*****.** .** ..::****.* ***. .... **.* **.:****** ***:*:**:*******.:***:::**:.**::*::**.*****..*:***:****:: ** . *:.::**::**** ***.*.*.:****.*:* ***:*:::***: :***.*. * *****", "identical_positions": 195, "similar_positions": 89, "identity": "61.13%" }, { "cls_id": "homologset.agr.MGI:1354373", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D4ADE6-1", "uniprot_id": "D4ADE6_RAT", "id": "D4ADE6-1", "name": "Sal-like protein 2", "aln": "MSRRKQRRPQQLISDCEG-----PSASENGDASEEDHPQVCAKCCAQFSDPTEFLAHQNACCTDPPVMVIIGGQENPSNSSVSSVPRPEGHSRPQVMDTEHSNLPDSGSSGPPDPAWGSERRGEE-------------SSGQFLVAGTGTAAGGGG--GLILASPKLGATPLPPESTPAPPPPPPPPP--PPGVGSGHLNIPLILEELRVLQQRQIHQMQMTEQICRQVLLLGSLGQTVG-APASPSELPGTGTASSTKPLLPLFSPIKPAQTGKTLASSSSSSSSS-GAEPPKQAFFHLYHPLGSQHP---------FSVGGVGRSHKPTPAPSPALPGSTDQLIASPHLAFPGTTGLLAAQCLGAARGLEAAASPGLLKP-KNGSGELGYGEVISSLEKPGGRHKCRFCAKVFGSDSALQIHLRSHTGERPYKCNVCGNRFTTRGNLKVHFHRHREKYPHVQMNPHPVPEHLDYVITSSGLPYGMSVPPEKAEEEAATPGGGVE----------------------RKPLVASTTALSATESLTLLSTGTSTAVAPGLP-------------------------TFNKFVLMKAVEPKSKVDENTPPGSEGSAISGVADSGSATRMQLS-KLVTSLPSWALLTNHLKSTGSFPFPYVLEPLG---------------ASPSETSKLQQLVEKIDRQ-----------------------------------------GAVAVASTASGAPTTSAPAPS-------SSAS-GPNQCVICLRVLSCPRALRLHYGQHGGERPFKCKVCGRAFSTRGNLRAHFVGHKTSP-AARAQNSCPICQKKFTNAVTLQQHVRMH-----LGGQIPNGGSTLPEGGGVAQENSSEQSTASG------------------------------------------------PGSFPQPQAQQPSAEEEISEEEEE-DEEEEEDVTDEDSLAGRGSESGGEKAISVRGDSE------------EVSGAE-------------------------------------------------------------------------------EEAATSGAAPTNGKE----------VDNNEKATQQALPPPPPPPDNLDRPQP------MEQGPSDVS-------------------GGMEEEAKLEGTSSPMAALPQEGEGTSTPSVEELNLPEAMKKEPGESSSRKACEVCGQSFPTQTALEEHQKTHPKD------GPLFTCVFCRQGFLDRATLKKHMLLAHHQ----------------------------------------------------------------------VPPFAPHGP----------------------------------QNIATLSLVPGCSSS-----------IPSPGLSPFPRKDDPAIP-----------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9QX96-1", "uniprot_id": "SALL2_MOUSE", "id": "Q9QX96-1", "name": "Sal-like protein 2", "aln": "MSRRKQRRPQQLISDCEG-----PSASENGDASEEDHPQVCAKCCAQFSDPTEFLAHQNSCCTDPPVMVIIGGQENPSNSSASSAPRPEGHSRSQVMDTEHSNPPDSGSSGAPDPTWGPERRGEE-------------SSGQFLVAATGTAAGGGG--GLILASPKLGATPLPPESTPAPPPPPPPPP--PPGVGSGHLNIPLILEELRVLQQRQIHQMQMTEQICRQVLLLGSLGQTVG-APASPSELPGTGAASSTKPLLPLFSPIKPAQTGKTLASSSSSSSSS-GAEPPKQAFFHLYHPLGSQHP---------FSVGGVGRSHKPTPAPSPALPGSTDQLIASPHLAFPGTTGLLAAQCLGAARGLEAAASPGLLKP-KNGSGELGYGEVISSLEKPGGRHKCRFCAKVFGSDSALQIHLRSHTGERPYKCNVCGNRFTTRGNLKVHFHRHREKYPHVQMNPHPVPEHLDYVITSSGLPYGMSVPPEKAEEEAGTPGGGVE----------------------RKPLVASTTALSATESLTLLSTGTSTAVAPGLP-------------------------TFNKFVLMKAVEPKSKADENTPPGSEGSAIAGVADSGSATRMQLS-KLVTSLPSWALLTNHLKSTGSFPFPYVLEPLG---------------ASPSETSKLQQLVEKIDRQ-----------------------------------------GAVAVASTASGAPTTSAPAPS-------SSAS-GPNQCVICLRVLSCPRALRLHYGQHGGERPFKCKVCGRAFSTRGNLRAHFVGHKTSP-AARAQNSCPICQKKFTNAVTLQQHVRMH-----LGGQIPNGGSALSEGGGAAQENSSEQSTASG------------------------------------------------PGSFPQPQSQQPSPEEEMSEEEEE-DEEEEEDVTDEDSLAGRGSESGGEKAISVRGDSE------------EVSGAE-------------------------------------------------------------------------------EEVATSVAAPTTVKE----------MDSNEKAPQHTLPPPPPPPDNLDHPQP------MEQGTSDVS-------------------GAMEEEAKLEGTSSPMAALTQEGEGTSTPLVEELNLPEAMKKDPGESSGRKACEVCGQSFPTQTALEEHQKTHPKD------GPLFTCVFCRQGFLDRATLKKHMLLAHHQ----------------------------------------------------------------------VPPFAPHGP----------------------------------QNIATLSLVPGCSSS-----------IPSPGLSPFPRKDDPTMP-----------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9Y467-1", "uniprot_id": "SALL2_HUMAN", "id": "Q9Y467-1", "name": "Sal-like protein 2", "aln": "MSRRKQRKPQQLISDCEG-----PSASENGDASEEDHPQVCAKCCAQFTDPTEFLAHQNACSTDPPVMVIIGGQENPNNSSASSEPRPEGHNNPQVMDTEHSNPPDSGSSVPTDPTWGPERRGEE-------------SSGHFLVAATGTAAGGGG--GLILASPKLGATPLPPESTPAPPPPPPPPP--PPGVGSGHLNIPLILEELRVLQQRQIHQMQMTEQICRQVLLLGSLGQTVG-APASPSELPGTGTASSTKPLLPLFSPIKPVQTSKTLASSSSSSSSSSGAETPKQAFFHLYHPLGSQHP---------FSAGGVGRSHKPTPAPSPALPGSTDQLIASPHLAFPSTTGLLAAQCLGAARGLEATASPGLLKP-KNGSGELSYGEVMGPLEKPGGRHKCRFCAKVFGSDSALQIHLRSHTGERPYKCNVCGNRFTTRGNLKVHFHRHREKYPHVQMNPHPVPEHLDYVITSSGLPYGMSVPPEKAEEEAATPGGGVE----------------------RKPLVASTTALSATESLTLLSTSAGTATAPGLP-------------------------AFNKFVLMKAVEPKNKADENTPPGSEGSAISGVAESSTATRMQLS-KLVTSLPSWALLTNHFKSTGSFPFPYVLEPLG---------------ASPSETSKLQQLVEKIDRQ-----------------------------------------GAVAVTSAASGAPTTSAPAPS-------SSASSGPNQCVICLRVLSCPRALRLHYGQHGGERPFKCKVCGRAFSTRGNLRAHFVGHKASP-AARAQNSCPICQKKFTNAVTLQQHVRMH-----LGGQIPNGGTALPEGGGAAQENGSEQSTVSG------------------------------------------------ARSFPQQQSQQPSPEEELSEEEEEEDEEEEEDVTDEDSLAGRGSESGGEKAISVRGDSE------------EASGAE-------------------------------------------------------------------------------EEVGTVAAAATAGKE----------MDSNEKTTQQSSLPPPPPPDSLDQPQP------MEQGSSGVL-------------------GGKEEGGKPERSSSPASALTPEGEATSVTLVEELSLQEAMRKEPGESSSRKACEVCGQAFPSQAALEEHQKTHPKE------GPLFTCVFCRQGFLERATLKKHMLLAHHQ----------------------------------------------------------------------VQPFAPHGP----------------------------------QNIAALSLVPGCSPS-----------ITSTGLSPFPRKDDPTIP-----------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9PFQ7-1", "uniprot_id": "A0A8M9PFQ7_DANRE", "id": "A0A8M9PFQ7-1", "name": "", "aln": "MSRRKQKRPQHFFSPILNTSWLLQHEEHPAVKPLTSTLE------QNSSSYSTRQSCKSTLNPTPPIERLKTSSPTRASHSVVHIPCQPLQLTLNLKGSNLSHIPDIPS-HLTNQCIKTTASSVSTHKHS----CLLMASPKLGVSATTTSSSSSSVAASLCVPPHPGSPSSGPQGPPSPVTPSSSPSTVPSAPACAPVSIAFILEELRVLQQRQIHQMQMTEEICRQVLRLGGGPCEVDSKPCILPSLPQFCLKGSDNNPRPSRPKSSSPPSSVAPLLACFSSLLPPQSSKHSNPLLNVLRPHKAQYDSVVTTPTNFTSHTSASTSSAMSTPVASNYPLTLSLGLP----TQKSSNTTGASGHSGLPFQNQSLPVAAVPSG-PSQDLKLSAQAGSSVLSSGRMQHACRFCRKLFSSDSSLQIHLRSHTGERPYQCPVCFSRFTTRGNLKVHFLRHREQNPELSFSLFPCSLFASVTGGSMGGSAQTQTVTSTNTNTTQRHQKQQ--DDDLCVDSLEGATASTRATASSLPPSIDLALLTTAHSLLQLNRAAAAAAAAAASTSTTSSITSSSSSSLASTLLSSPASSTSSIAGVYKGVKQQRFDENTPPIPTLLPHTAYSQLANLPKIFFPASSSHHHLGHGFLRPTSPAGSFLPSPQHHITFP----FTSSSTAPSISTPTSDTSKLQRLVEKLEKEPHGQTNWESSIGETSTSGNSVSGTLTYSSSGLMSTSTYSTNVVTSLPSSTVQIPSSLFSKESPYMGLMNSAGTLAPNQCSVCLRVLSCPRALRLHQATHLGERPFPCKLCGRSFSTKGSLRAHLATHRARPPNSRAQNSCPLCQRKFTNALVLQHHIRMH-----LGGQLPPEHMPDTSTECDSQSHSQSIEPSGSENTPSTVDVQLLHADRQTISDSSHTESLAVSIAPTVCPVTSSLPASRSSGPIPTFDLSPGPSLNLTPQSPPTFIADPPELSLNIPSPVESAASLFPPTSQSASTSGTTANDEVCFELSSNTAYLG-------------------------------------------------------------------------------DISSTSALMNTSPQENDCEVSENRSLSAVPCSGSRSNLEDLLSIQAHNASRASRTHPVSPPSSPLVL-------------------GSESVSSQNVRLEEPDQSLVQTSTSLPQEFPNEQKTEDKGRKTPKNGQKIPPELSTDQEMLSDTVTKTSEDAVESEEADTRVQKITKDTHYSSDAMDKADLNDATATEMDR----------------------------------------------------------------------TEPTVCISLTPSLPPPM--------------PEKKIYHCSECGKEYASRSGLKGHMKHHGGVVKTPRAPARTKGPEKVMHNDRPQSHNLATYLPPGHE------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A0R4I9L7-1", "uniprot_id": "A0A0R4I9L7_DANRE", "id": "A0A0R4I9L7-1", "name": "", "aln": "MSRRKQKRPQQLVNADPGGTRLMPQEDQLQVKSPSTSLASEATSSSSSSSPTSLQDCQPPLAPRPSPGGLHAPSLPNESSSPPHWPNHIASYSTSLPNAHSSLSPDFPHPSLSSQTHSPPPGQQKSTRISSHQPHSTVTSPPMGISATTTTSSLSS-SSSLGAPPHQGSPS------PIHQTPSS-----PSEQLQVPPTLAVLLEELRVLQQRQIHQMQITEEICRQVLRLGG--------MVSAPDAPQGSVEGQQRDAG-----SSSPPNGVS-----GASLIN--QAPVSKPNLSQTNGGRAPYS---------TTSSSTSSSSSLVTSTATVHPLSLTLGLPPRYLNEKSANTPISHGN-GLNFQTSPLPTVSISQDQLSHSSTVSTSNGSSSSSSGRQQHICRFCGKVLSSDSSLQIHLRSHTGERPYQCPVCLSRFTTRGNLKAHFLRHREQNPELSLSLLPPALSEQSQSGSGSGGSQRRRKRRAEDEEPFGVKGSVGVPDSLALGFLSGPAHPS-PSSLPLPPSVDLALLSTAHSLLQLNRASAAAAASVS-----PSVQSSSSS-----------ITSSAMTGQLKGSKQQRFDENTPPHPTLHHGSPYSQLAHLPKILFPSGPSAHHPSLALLRPPHLTSPHLPLTFPFSSYPKPQNSSPPSSSPSSSSATSDTSKLQRLAQKLEKQPLPKSTNE---GQTNTQANDIS-----TSSNAISAYRREMMAALGLNPNPSSEPTSQEIQGS-------AASSLVPNQCGVCLRVLSCPRALRLHQATHLGERPFPCKLCGRSFSTKGSLRAHLATHRARPANARGQNSCPLCQRKFTNAVVLQHHIRMH-----LGGQLPPEVNGDLQSE-DAHSQIDGISLPKS--------LQSLPLNMSMSSAASLLDSGAILRDP-------------TSGDTDQLMESDQDPYENTSENSPTFTLEKQDPSREN-SPLDNSVALEENHYVTVHHSKS--------QVVNGSAHKD-------------------------------------------------------------------------------EDTPLSLCTRTSSQD---PLFDKKWQNGASHHTVISGPKPSLSSEALDLSPA-----LTPPSSPGLE-------------------SKPDQSSEQTTLHVNGIDHVPEFKDADSHPAPENVIEHKLKADDTQESKMEESAVEDHKKDSEKTEVTSSEAPVAQ--PQRSEKPYSCTECGKEYASRSGLKGHMKIHSGS----------------------------------------------------------------------MNQVAGTASSQSS-----------------------------GGKVAERMEESTHRKLRGEDAKN----LSEESTDKLSLTEHPASTTDRTEDTA---------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VKH3-1", "uniprot_id": "Q9VKH3_DROME", "id": "Q9VKH3-1", "name": "", "aln": "MCSIFRNRINYRGTGGTR-----SGSGERERDRDRDRDRDRDRERDRDTLLAKELDADSNNNGTEPQMEAEAVPESDTERETAEERGEEQEPENSNEALDLSLISSGGRESLPGSGHVSLEALQH---------------TKVAVAQFAATAMAGN---------------------------------------HQSADLAMVQSTIFNVQRQHLMQLQLIQHLQSQLKRAEAAALG-----------RHSHSDEEEEEPEPEPEPKKQPTNGLKEELELEQGPESEQDQESRREENSKTDKRGTEDR---------------KAEPEGYQSMMCDISSSLASSIITNHDPPPAPNEPNCLEMLQRRTEEVLDSASQSLHAAQMQEEYSEYASKEAQSRGEIFKHRCKYCGKIFGSYSALQIHLRSHTGERPFVCNVCGSKFTTKGNLKVHYQRHTQIFPPMLLPPGVAPNVGHSGQGQVQGEQYPIRLPFAPPVAPVGQEQHQN------------------QVEEPEEIRQEIPVPQAEDLSKPMVKEKEKSHSPVER--------------------------VKTPKEVKTDAALPSSEKPEKEISKPVVTSSRRNGSVRKRQTSAVSPPQEDRERDLVEHLHIAKLVRRSSASRESQP----------------AEYSLAQMERIIDKSWED----------------------------------------LIEIDKTSETSKLQQLVDNIEN---------KLTDPNQCIFCQKVMSCRSSLQMHIRTHTGERPFRCKICGRAFATKGNLKAHMSIHKIKP-PMRSQFKCPVCHQKFSNGIILQQHIRIHTMDDGSGGQGAPAANPGEAERLGIEDQNSNKSLGTSDTLDFSTTISDHSGQRSESSQGGDFDEFMTMDSTDD-------SRDNSSAATATPHPLERERDREKERERRIPNDCSDERSHSNPDLTGGRSESGEMPAMDLSSPSSNSGRIFATGLANGAAGGGSGNGGLPMLGMPMPPNLLLMAAAREEMHALGHAHAKFPLLPFGPLGFMGLHPPPNVCNLCFKMLPSLAALESHLQSEHAKEPATGHAQRPQCSDAGSPYGAKLTLNPNLFAKKPPSSSSSSSGEKLPESSNPPFPAENPPATPIKEDPDQEQLMVEEGASAGEGSGTGATSNYPQEAGDAEQSLMKMQLHAHRFPASPLDFQQALMSAGPPTSSLDPPVNNKHFCHVCRRNFSSSSALQIHMRTHTGDKPFQCNVCQKAFTTKGNLKVHMGTHMWTNPTSRRGRRMSLELPMRPGPNSGQGHPGSSAEQEFMQRRPELFFPYLPPFFNGLPPKPGELSPGAFPNIPPPPFANGGKYPYPPGLLGFPGFLAQHPYILERRSSSKSPTPEPAQSPALREEEGSGNIWHPLSRIKVENNQNESMGGFNEQEDHAETDATGGDNDESESRDAEK", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*. :.: : . . : : . . . . . . * .. .. . . :: ::: .. :..: . : :*:::: *:*: :.: *: . . . . .. . . : . . . : : ... . . . . :* *::* *::.* *:*************: * ** .:***:****.*: ** : * : : . . . . . : . : : :. . :: . : : . : . :: : . . . . :::::: :* .: . . . **** .* :*:** :*::* * ***** **:***:*:*:*.*:**: *: * *.* .**:*::**:*.: **:*:*:* *** . ..: . . . . . .. : . . : . . .: . . . : . ... . . . : ..: . . :. *: . . : . . . : ", "identical_positions": 86, "similar_positions": 192, "identity": "5.85%" }, { "cls_id": "homologset.agr.MGI:1354380", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9QZ29-1", "uniprot_id": "IGB1B_MOUSE", "id": "Q9QZ29-1", "name": "Immunoglobulin-binding protein 1b", "aln": "MASFTEEMQKP-KLRELLETGIQLLEEVEAATQPTGSKPIQEKVREALKLLEKASDMLSQLDLFSRNEDWEEIASADLKYLMLPALKGALTLKLVG--------SSKRLGLLQDAREHFMNFLTQTHSYHVADFQL----PWAQSSSMEGNP-AATSDAQEQNLVAMASQRQTKIQRYKQKKAVEQRLSSLKSAVESGQAD---DERVREYYLLQLRRWISISLDEIENI-------------------EQEIEILRERDSLGETSASRSSPQ----------------ERPPLKPFVLTRSVAQAQVFGAGYPSLATMTVNDWYEQRQK-----NEVSPTLQEAEKQAPPSETFTVSEKEEPDLE-------QKEDEDENALHRMQEWDDWKDTHPRGYGNRQNMG", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0ABK0L7W7-1", "uniprot_id": "A0ABK0L7W7_RAT", "id": "A0ABK0L7W7-1", "name": "", "aln": "MAAFMDEQQKP-KLRELLETGIELLEEVEATTQPTGSKQIQEK----------ASEMLSQLDLFSRNEDWEEIASADLKYLMLPALKGALTLKLVG--------TSNRLHLLQDARELFMNFLTQSHNYHVAEFQL----PWAQSSSQESNPAAATSDTLEHNLVAMASQRQAKIQRYKQKKAVEQRLSSLKSAVESGEAD---DERVREYYLLQLRRWINISLDEIDSI-------------------DQEIEILRERDSFGEASVSQGSPQ----------------ERPPLKPFVLTRSVAQAQVFGAGYPSLATLTVNDWYEQRQK-----GEVSSSVREAEKQAPPLETLSVSEPEKPDLE-------QKEEEDENALHRMQEWDDWKDTHPRGYGNRQNMG", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0A1W2PR95-1", "uniprot_id": "IGB1C_HUMAN", "id": "A0A1W2PR95-1", "name": "Immunoglobulin-binding protein 1 family member C", "aln": "MAAAEDEFLPPPRLPELFDSSKQLLDEVEGATEPTGSRIVQEKVFKGLDLLDKVAKMLSQLDLFSRNEDLEEITSTDLKYLMVPAFQGALTMKQVN--------PRKRLDHLQQAREHFIKYLTQCHYYRVAEFEL----PQTKTNSAENHG--AITSTAYPSLVAMASQRQAKIERYKQKKVLEHKLSTMKSAVESGQAD---NERVREYYLLHLQRWIDISLEEIESI-------------------DQEIKILGEKDSSREASTSNSCHQ----------------KRPPMKPFILTRNMAQAKVFGAGYPSLASMTVSDWYDQHQK-----HGVLP--DQGIAKATP-EEFRKATQQQEDQE-------KEEEDDEQTLQRAREWDDWKDTHPRGYGNRQNMG", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VJZ5-1", "uniprot_id": "Q9VJZ5_DROME", "id": "Q9VJZ5-1", "name": "", "aln": "MAEGNTAGGEDQKLTDIFLKGWNIFDELEVTELPFNGSEFQNKVKTAMGLFEQATVIVNQVSMFSANELIDEVSTESLPFMLLPYFLGKLTTKINS--------PNN-THSIELGEIYFKDHLQRCQEYDLCAAPK----SQVAKADSQAEK------SEQRELVEAAFNRNDKIAQYRRMKEIDEYMARMRDAVKNKTVD---DEDKRVFFLKYLDKSIIDSKQELETLGVMKQLAQMRLARLAGGESDNEVDSFRPPNQNQSSASSTSRGHGHSHGPGHHHHHQQAAKPKPLQPFIITRNATQKAVFGLGYPSLPIMTVDEFYQQRVD-----EGIFPDEEKVAKMNQAQAIAAARDPNEKEDEEKAVEELQAEQDDPEYIDRMRRMDEYKDVVRRGDGNRHNRS", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q04372-1", "uniprot_id": "TAP42_YEAST", "id": "Q04372-1", "name": "Type 2A phosphatase-associated protein 42", "aln": "MASVTEQFNDIISLYSTKLEHTSLRQDSPEYQGLLLST--------IKKLLNLKTAIFDRLALFSTNETIDDVSTASIKFLAVDYYLGLLISRRQSNDSDVAQRQSMKLIYLKKSVESFINFLTLLQDYKLLDPLVGEKLGNFKDRYNPQLSELYAQPKNNKDLSGAQLKRKEKIELFQRNKEISTKLHCLELELKNNDEDHDHDELLRELYLMRLHHFSLDTINNIEQN-----------------LFECEMLSNFLKNSVHEVKSSGTQIRKESND----------DDSTGFTDKLENINKPLIDKKGQVLRNFTLVDKRQQLQQKVRGYGQYGPTMSVEEFLDKEFEEGRVLQGGEEPEQAPDE------ENMDWQDRETYKAREWDEFKESHAKGSGNTMNRG", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "** * . .: :: . : :..:: :** ** ::::: .: :: : * * : . :: . * ..* : * : .* :*: ** ::: * :. : :. ::. * :* * :* * : : :::: : *: :. . * : . : : . . . * .:. : : :*: . : : : : : . : :. *::*: :* ** * .", "identical_positions": 32, "similar_positions": 88, "identity": "7.86%" }, { "cls_id": "homologset.agr.MGI:1354381", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q6P7D7-1", "uniprot_id": "Q6P7D7_RAT", "id": "Q6P7D7-1", "name": "Transmembrane protease serine 2", "aln": "MALNSGSPPGIGPYYENHGYQSEHVYSPRPPVSPSGYNLYPAQSCPSPVPQYAPRVTTQASTPAIHIQPRS-SGTLCTSKSKKSMLVALALGTVLAGAAVAAGLLWKFWDSKCSSSEMECGSSGTCISSSLWCDGVSQCPNGEDENRCVRLYGTSFTLQVYSSQRKAWYPVCQDDWNESYGRAACKDMGYKNSFYSSQGIPDQSGATSFMKLNVSAGNVDLYKKLYHSDSCSSRMVVSLRCIECGVRS-VRRQSRIVGGSTASPGDWPWQVSLHVQG---IHVCGGSIITPEWIVTAAHCVEEPLSSPRYWTAFAGILKQSLMFYGSRHQVEKVISHPNYDSKTKNNDIALMKLQTPLAFNDVVKPVCLPNPGMMLDLAQECWISGWGATYEKGKTSDVLNAAMVPLIEPSKCNSKYIYNNLITPAMICAGFLQ-GSVDSCQGDSGGPLVTLKNEIWWLIGDTSWGSGCAKAYRPGVYGNVTVFTDWIYQQMRANS----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9JIQ8-1", "uniprot_id": "TMPS2_MOUSE", "id": "Q9JIQ8-1", "name": "Transmembrane protease serine 2", "aln": "MALNSGSPPGIGPCYENHGYQSEHICPPRPPVAPNGYNLYPAQYYPSPVPQYAPRITTQASTSVIHTHPKS-SGALCTSKSKKSLCLALALGTVLTGAAVAAVLLWRFWDSNCSTSEMECGSSGTCISSSLWCDGVAHCPNGEDENRCVRLYGQSFILQVYSSQRKAWYPVCQDDWSESYGRAACKDMGYKNNFYSSQGIPDQSGATSFMKLNVSSGNVDLYKKLYHSDSCSSRMVVSLRCIECGVRS-VKRQSRIVGGLNASPGDWPWQVSLHVQG---VHVCGGSIITPEWIVTAAHCVEEPLSSPRYWTAFAGILRQSLMFYGSRHQVEKVISHPNYDSKTKNNDIALMKLQTPLAFNDLVKPVCLPNPGMMLDLDQECWISGWGATYEKGKTSDVLNAAMVPLIEPSKCNSKYIYNNLITPAMICAGFLQ-GSVDSCQGDSGGPLVTLKNGIWWLIGDTSWGSGCAKALRPGVYGNVTVFTDWIYQQMRANS----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O15393-1", "uniprot_id": "TMPS2_HUMAN", "id": "O15393-1", "name": "Transmembrane protease serine 2", "aln": "MALNSGSPPAIGPYYENHGYQPENPYPAQPTVVPTVYEVHPAQYYPSPVPQYAPRVLTQASNPVVCTQPKSPSGTVCTSKTKKALCITLTLGTFLVGAALAAGLLWKFMGSKCSNSGIECDSSGTCINPSNWCDGVSHCPGGEDENRCVRLYGPNFILQVYSSQRKSWHPVCQDDWNENYGRAACRDMGYKNNFYSSQGIVDDSGSTSFMKLNTSAGNVDIYKKLYHSDACSSKAVVSLRCIACGVNLNSSRQSRIVGGESALPGAWPWQVSLHVQN---VHVCGGSIITPEWIVTAAHCVEKPLNNPWHWTAFAGILRQSFMFYGAGYQVEKVISHPNYDSKTKNNDIALMKLQKPLTFNDLVKPVCLPNPGMMLQPEQLCWISGWGATEEKGKTSEVLNAAKVLLIETQRCNSRYVYDNLITPAMICAGFLQ-GNVDSCQGDSGGPLVTSKNNIWWLIGDTSWGSGCAKAYRPGVYGNVMVFTDWIYRQMRADG----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VR15-1", "uniprot_id": "Q9VR15_DROME", "id": "Q9VR15-1", "name": "Peptidase S1 domain-containing protein", "aln": "------------------------------------------------------------------------------------MRVYLALPLLLLGIG----LSLAQYQYQAP---------------------------------------------------HQTLAQQFADVVDVVDPAEQSIKAVRPPKSRNQCTAKQN-------------------------------------CFCGTPN----VNRIVGGQQVRSNKYPWTAQLVKGRHYPRLFCGGSLINDRYVLTAAHCVHG--NRDQ-ITIRLLQIDRSSRDPGIVRKVVQTTVHPNYDPNRIVNDVALLKLESPVPLTGNMRPVCLP-EANHNFDGKTAVVAGWGLIKEGGVTSNYLQEVNVPVITNAQCR-QTRYKDKIAEVMLCAGLVQQGGKDACQGDSGGPLIVN-EGRYKLAGVVSFGYGCAQKNAPGVYARVSKFLDWIRKNTADGCYCQS", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VUF0-1", "uniprot_id": "Q9VUF0_DROME", "id": "Q9VUF0-1", "name": "Peptidase S1 domain-containing protein", "aln": "------------------------------------------------------------------------------------MKLNPPAFLLLLALISICDRSWAVYNYKPPSR-------GYFYPKPERLPPLPVNGSTTSSTGPPPGVQSDFIDDLIEGHKQQILSNVLGVASETPSDTASSLGSTSLSSSASPVFPLEGGGAKAFRVNRCAS------------------------CTCGVPN----VNRIVGGTQVRTNKYPWIAQIIRG---TFLFCGGTLINDRYVLTAAHCVHG--MDMRGVSVRLLQLDRSSTHLGVTRSVAFAHAHVGYDPVSLVHDIALLRLDQPIPLVDTMRPACLPSNWLQNFDFQKAIVAGWGLSQEGGSTSSVLQEVVVPIITNAQCR-ATSYRSMIVDTMMCAGYVKTGGRDACQGDSGGPLIVR-DRIFRLAGVVSFGYGCAKPDAPGVYTRVSRYLEWIAVNTRDSCYCIN", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : . .* . : . : . : . : . . :. **. .***** . .. :** ..: .***::*. .:::******. : : :* * .* . * .**. :*:**::*: *:.: . ::*.*** : . ::*** * * **. *: . * :* :*. * . *. .*:*** :: *. *:*********:. : : * * .*:* ***: **** .* : :** : . ", "identical_positions": 77, "similar_positions": 83, "identity": "15.4%" }, { "cls_id": "homologset.agr.MGI:1354385", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8R180-1", "uniprot_id": "ERO1A_MOUSE", "id": "Q8R180-1", "name": "ERO1-like protein alpha", "aln": "MGR--------AWGLLVGLLGVVWLLRLGHGEERRPETAAQR-CFCQVSGYLDDCTCDVETIDKFNNY--RLFPRLQKLLESDYFRYYKVNLKKPCPFWNDIN-QCGRRDCAVKPCHSDEVPDGIKS-------ASYKYSEEAN-RIEECEQAE----RLGAVDESLSEETQKAVLQWTKHDDSSDSFCEIDDIQSPDAEYVDLLLNPERYTGYKGPDAWRIWSVIYEENCFKPQTIQR---PLASGRGKSKENTFYNWLEGLCVEKRAFYRLISGLHASINVHLSARYLLQDT--WLEKK--WGHNVTEFQQRFDGILTEGEGPRRLRNLYFLYLIELRALSKVLPFFERPDFQLFTGNKVQDAENKALLLEILHEIKSFPLHFDENSFFAGDKNEAHKLKEDFRLHFRNISRIMDCVGCFKCRLWGKLQTQGLGTALKILFSEKL-------IANMPESGPSYEFQLTRQEIVSLFNAFGR-----------------------ISTSVRELENFRHLLQNVH--------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8R4A1-1", "uniprot_id": "ERO1A_RAT", "id": "Q8R4A1-1", "name": "ERO1-like protein alpha", "aln": "MGR--------GWGLLVGLLGVVWLLRSGQGEEQQQETAAQR-CFCQVSGYLDDCTCDVETIDKFNNY--RLFPRLQKLLESDYFRYYKVNLRKPCPFWNDIN-QCGRRDCAVKPCHSDEVPDGIKS-------ASYKYSKEAN-LLEECEQAE----RLGAVDESLSEETQKAVLQWTKHDDSSDSFCEVDDIQSPDAEYVDLLLNPERYTGYKGPDAWRIWSVIYEENCFKPQTIQR---PLASGQGKHKENTFYSWLEGLCVEKRAFYRLISGLHASINVHLSARYLLQDN--WLEKK--WGHNVTEFQQRFDGVLTEGEGPRRLKNLYFLYLIELRALSKVLPFFERPDFQLFTGNKVQDVENKELLLEILHEVKSFPLHFDENSFFAGDKNEAHKLKEDFRLHFRNISRIMDCVGCFKCRLWGKLQTQGLGTALKILFSEKL-------IANMPESGPSYEFQLTRQEIVSLFNAFGR-----------------------ISTSVRELENFRHLLQNVH--------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q96HE7-1", "uniprot_id": "ERO1A_HUMAN", "id": "Q96HE7-1", "name": "ERO1-like protein alpha", "aln": "MGR--------GWGFLFGLLGAVWLLSSGHGEEQPPETAAQR-CFCQVSGYLDDCTCDVETIDRFNNY--RLFPRLQKLLESDYFRYYKVNLKRPCPFWNDIS-QCGRRDCAVKPCQSDEVPDGIKS-------ASYKYSEEANNLIEECEQAE----RLGAVDESLSEETQKAVLQWTKHDDSSDNFCEADDIQSPEAEYVDLLLNPERYTGYKGPDAWKIWNVIYEENCFKPQTIKRPLNPLASGQGTSEENTFYSWLEGLCVEKRAFYRLISGLHASINVHLSARYLLQET--WLEKK--WGHNITEFQQRFDGILTEGEGPRRLKNLYFLYLIELRALSKVLPFFERPDFQLFTGNKIQDEENKMLLLEILHEIKSFPLHFDENSFFAGDKKEAHKLKEDFRLHFRNISRIMDCVGCFKCRLWGKLQTQGLGTALKILFSEKL-------IANMPESGPSYEFHLTRQEIVSLFNAFGR-----------------------ISTSVKELENFRNLLQNIH--------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q7T3D1-1", "uniprot_id": "ERO1A_DANRE", "id": "Q7T3D1-1", "name": "ERO1-like protein alpha", "aln": "MET--------CVLLLGLFLTSVHVTTAG--------SAAHR-CFCQVTGTLDDCACDVETIDKFNNK--DIFPKLQKLLSSDYFRFYKVNLNNGCPFWTDHS-QCGLKYCAVKPCSPDEVPEGLKS-------SSYKYSEKASHDTEECEKAE----KLGAVNGSLSDETRQALEEWKKYDDESDRFCMLDDEDSPESQYVDLLLNPERFTGYKGAEAWRIWNSIYEENCFKPYSVNRPLNPLASNSGDDGQG-FYRWLEGLCVEKRAFFRLISGLHASINIHLSARYLLDEN--WFEMK--WGHNVSEFQQRFDEDLTKGEGPKRLRNLYFLYLIELRALAKILPYFERSTFQLYTGQDTQDDQNKKLLLELLHVAKSFPLHFDETALFAGNNKEAMKLKEDFKLTFKNISRIMDCVECFKCRLWGKLQTQGLGTALKILFSERQ-------IEAMPNKQHQSIISAQSAGNCVFVQRFRKNLHKCQRVEELQIVV-----VETQTVTVKMFQERATVQTDMHKHMTFPMFGYIQ--------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9V3A6-1", "uniprot_id": "ERO1L_DROME", "id": "Q9V3A6-1", "name": "Ero1-like protein", "aln": "MTTRTVQRNLWASAAVVLVLLLLWTDTTGGYFAAIDETETSKNCFCELEGSINDCSCDVDTVDHFNNM--KIYPRLQSLLVKNFFRFYKVNLRQECPFWPDDS-RCAMRFCQVENCEEQAIPQGIKDKGEHKEKAAFKYTREAQVGGSACSDGEDFDSSLGFLDTSISDQAHREFELWAKHDEAEEDFCIVDDHEE-GSQYVDLLLNPERYTGYKGESAHRIWKSIYLENCFGGN---------NETANKFSNYVPHLDLRNVCLEQRAFYRIISGLHSSINIHLCSKYLLSESKDFLDPQGIWGPNVKEFKRRFSPETTSGEGPHWLRNLYFIYLIELRALAKAAPYLRREDY--YTGIAEEDDEVKLAINDMLSVIENFQSHFDENALFS-NGIASIKFKHDYKEKFRNISRIMSCVGCDKCKLWGKLQTQGLGTALKILYSEKLNLATESGLWDKPHIEADPIFRLSRTEIVALFNAFGR-----------------------LSNSIYEMENFRCVLR-----------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q03103-1", "uniprot_id": "ERO1_YEAST", "id": "Q03103-1", "name": "Endoplasmic oxidoreductin-1", "aln": "MRLR------TAIATLCLTAFTSATSNNSYIATDQTQNAFNDTHFCKVDRNDHVSPSCNVTFNELNAINENIRDDLSALLKSDFFKYFRLDLYKQCSFWDANDGLCLNRACSVDVVEDWDTLP-----------EYWQPEILGSFNNDTMKEAD------DSDDECKFLDQLCQTSKKPVDIEDTINYCDVNDFNGKNAVLIDLTANPERFTGYGGKQAGQIWSTIYQDNCFTIG------------------------ETGESLAKDAFYRLVSGFHASIGTHLSKEYLNTKTG-------KWEPNLDLFMARIG------NFPDRVTNMYFNYAVVAKALWKIQPYLPEFSFCDLVNKEIKNKMDN-VISQLDTKIFNEDLVFAN--------DLSLTLKDEFRSRFKNVTKIMDCVQCDRCRLWGKIQTTGYATALKILFEIND---------ADEFTKQHIVGKLTKYELIALLQTFGRLSESIESVNMFEKMYGKRLNGSENRLSSFFQNNFFNILKEAGKSIRYTIENINSTKEGKKKTNNSQSHVFDDLKMPKAEIVPRPSNGTVNKWKKAWNTEVNNVLEAFRFIYRSYLDLPRNIWELSLMKVYKFWNKFIGVADYVSEETREPISYKLDIQ", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* : . . **:: . ... *.:.:* : *. ** .::*::::::* . *.** . * : * *. :: .. . ...: . : . : : :* :* : : :** ****:*** * .* :**. ** :*** . .: : **:*::**:*:**. **. .** .. * *: * *:. : * : *:** * : :** * *:: . : .. :: : : :: . * : : .:*.::: *:*:::**.** * :*:****:** * .******:. . :.: * : : :: : ", "identical_positions": 85, "similar_positions": 116, "identity": "13.26%" }, { "cls_id": "homologset.agr.MGI:1354386", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A0G2K4A8-1", "uniprot_id": "A0A0G2K4A8_RAT", "id": "A0A0G2K4A8-1", "name": "non-specific serine/threonine protein kinase", "aln": "MRPKTFP--ATTYSGNSRQRLQEIREGLK--QPAKSSTQGLLVGPNSDTSSLDAKVLGNKDASRQQQ-MRATPKFGPYQKALREIRYSLLP-------FANESG----TSAAAEVNRQMLQELVNAGCDQEMAGRALKQTGSRSIEAALEYISKMGYLD-PRNEQIVRVIKQTSPGKGLVPTAVTRRPSFEGTG-EAFPSHHQLGGANYEG-------PAALEEMPR--QYLDFLFP------------------GASVHG-APAHQHPP------------KGYSTAVDAG-THFP----------------GAHYG-RAHLLS--EQPGYGVQRSPSFQSKTPPDT---YSSL-AKAQGGPP-ASLTFP-AHAGLYTTSHHKPAAAVPGAHPLHVLGTRGPTFTGDSS------TQAVLAPSRNSLNNDLYELGSP--VPWPAAPLARRDSLQKQSLEAS----RPHVAFR---AGPSRTNSFSSPQP-----------------EPSLPAPNTVTAVTAAHILHPVKSVRVLRPEPQTAVGPSHPAWVPAP-TAPA-----AAEGLESKE------GSAGPPPLDMDFGGSERRCPPPPYPKHLLLP-------SKSEQYSAGLDRLCTG--------VEQSLRGG-TEQDRNDKGHKGAKGDKAGRDKKQIQTSPVPVRK---NSRDEEKRESRIKSYSPYAFKFFMEQHVENVIKTYQQKVSRRLQLEQEMAKAGLCETEQEQMRKILYQKESNYNRLKRAKMDKSMFVKIKTLGIGAFGEVCLACKVDTH-ALYAMKTLRKKDVLNRNQVAHVKAERDILAEADNEWVVKLYYSFQDKDSLYFVMDYIPGGDMMSLLIRMEVFPEHLARFYIAELTLAIESVHKMGFIHRDIKPDNILIDLDGHIKLTDFGLCTGFRWTHNSKYYQK-GNHIRQDSMEPGDLWDDVSNCRCGDRLKTLEQRAQKQHQRCLAHSLVGTPNYIAPEVLLRKGYTQLCDWWSVGVILFEMLVGQPPFLAPTPTETQLKVINWENTLHIPTQVKLSAEARDLITKLCCAADCRLGRDGADDLKAHPFFSTIDFSRDIRKQPAPYVPTISHPMDTSNFDPVDEES---PWHEASGESAKAWDTLASPNSKHPEHAFYEFTFRRFFDDNGYPFRCPKPS----EPAES----------ADPGDAELGGAVEGCQPVYV", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q7TSJ6-1", "uniprot_id": "LATS2_MOUSE", "id": "Q7TSJ6-1", "name": "Serine/threonine-protein kinase LATS2", "aln": "MRPKTFP--ATTYSGNSRQRLQEIREGLK--QPSKASTQGLLVGPNSDTS-LDAKVLGSKDASRQQQ-MRATPKFGPYQKALREIRYSLLP-------FANESG----TSAAAEVNRQMLQELVNAGCDQEMAGRALKQTGSRSIEAALEYISKMGYLD-PRNEQIVRVIKQTSPGKGLAPTPVTRRPSFEGTG-EALPSYHQLGGANYEG-------PAALEEMPR--QYLDFLFPGA----------------GAGTHG-AQAHQHPP------------KGYSTAVEPS-AHFP----------------GTHYG-RGHLLS--EQPGYGVQRSSSFQNKTPPDA---YSSM-AKAQGGPP-ASLTFP-AHAGLYTASHHKPAATPPGAHPLHVLGTRGPTFTGESS------AQAVLAPSRNSLNADLYELGST--VPWSAAPLARRDSLQKQGLEAS----RPHVAFR---AGPSRTNSFNNPQP-----------------EPSLPAPNTVTAVTAAHILHPVKSVRVLRPEPQTAVGPSHPAWVAAP-TAP------ATESLETKE------GSAGPHPLDVDYGGSERRCPPPPYPKHLLLP-------SKSEQYSVDLDSLCTS--------VQQSLRGG-TEQDRSDKSHKGAKGDKAGRDKKQIQTSPVPVRK---NSRDEEKRESRIKSYSPYAFKFFMEQHVENVIKTYQQKVSRRLQLEQEMAKAGLCEAEQEQMRKILYQKESNYNRLKRAKMDKSMFVKIKTLGIGAFGEVCLACKLDTH-ALYAMKTLRKKDVLNRNQVAHVKAERDILAEADNEWVVKLYYSFQDKDSLYFVMDYIPGGDMMSLLIRMEVFPEHLARFYIAELTLAIESVHKMGFIHRDIKPDNILIDLDGHIKLTDFGLCTGFRWTHNSKYYQK-GNHMRQDSMEPGDLWDDVSNCRCGDRLKTLEQRAQKQHQRCLAHSLVGTPNYIAPEVLLRKGYTQLCDWWSVGVILFEMLVGQPPFLAPTPTETQLKVINWESTLHIPTQVRLSAEARDLITKLCCAADCRLGRDGADDLKAHPFFNTIDFSRDIRKQPAPYVPTISHPMDTSNFDPVDEES---PWHEASGESAKAWDTLASPSSKHPEHAFYEFTFRRFFDDNGYPFRCPKPS----EPAES----------ADPGDADLEGAAEGCQPVYV", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9NRM7-1", "uniprot_id": "LATS2_HUMAN", "id": "Q9NRM7-1", "name": "Serine/threonine-protein kinase LATS2", "aln": "MRPKTFP--ATTYSGNSRQRLQEIREGLK--QPSKSSVQGLPAGPNSDTS-LDAKVLGSKDATRQQQQMRATPKFGPYQKALREIRYSLLP-------FANESG----TSAAAEVNRQMLQELVNAGCDQEMAGRALKQTGSRSIEAALEYISKMGYLD-PRNEQIVRVIKQTSPGKGLMPTPVTRRPSFEGTG-DSFASYHQLSGTPYEGPSFGADGPTALEEMPR--PYVDYLFP------------------GVGPHGPGHQHQHPP------------KGYGASVEAAGAHFPLQ--------------GAHYG-RPHLLVPGEPLGYGVQRSPSFQSKTPPETGG-YASLPTKGQGGPPGAGLAFPPPAAGLYVPHPHHKQAG-PAAHQLHVLGSRSQVFASDSP------PQSLLTPSRNSLNVDLYELGSTSVQQWPAATLARRDSLQKPGLEAPP---RAHVAFRPDCPVPSRTNSFNSHQPRPG---------PPGKAEPSLPAPNTVTAVTAAHILHPVKSVRVLRPEPQTAVGPSHPAWVPAPAPAPAPAPAPAAEGLDAKEEHALALGGAGAFPLDVEYGGPDRRCPPPPYPKHLLLR-------SKSEQY--DLDSLCAG--------MEQSLRAGPNEPEGGDKSRKSAKGDKGGKDKKQIQTSPVPVRK---NSRDEEKRESRIKSYSPYAFKFFMEQHVENVIKTYQQKVNRRLQLEQEMAKAGLCEAEQEQMRKILYQKESNYNRLKRAKMDKSMFVKIKTLGIGAFGEVCLACKVDTH-ALYAMKTLRKKDVLNRNQVAHVKAERDILAEADNEWVVKLYYSFQDKDSLYFVMDYIPGGDMMSLLIRMEVFPEHLARFYIAELTLAIESVHKMGFIHRDIKPDNILIDLDGHIKLTDFGLCTGFRWTHNSKYYQK-GSHVRQDSMEPSDLWDDVSNCRCGDRLKTLEQRARKQHQRCLAHSLVGTPNYIAPEVLLRKGYTQLCDWWSVGVILFEMLVGQPPFLAPTPTETQLKVINWENTLHIPAQVKLSPEARDLITKLCCSADHRLGRNGADDLKAHPFFSAIDFSSDIRKQPAPYVPTISHPMDTSNFDPVDEES---PWNDASEGSTKAWDTLTSPNNKHPEHAFYEFTFRRFFDDNGYPFRCPKPSGAEASQAES----------SDLESSDLVDQTEGCQPVYV", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "B0S8I4-1", "uniprot_id": "B0S8I4_DANRE", "id": "B0S8I4-1", "name": "non-specific serine/threonine protein kinase", "aln": "MRPKTFP--ATPYVGNTRQRLQDIKEGLK--QPAKLVSQALHGGSSRGEGGRGGDSKGKDQAARQQQ-LRPPQKFNNYQSALREIRKSLRP-------YANDSGPGSSSGHPGEVSRQMLQDLVNAGCDQEMAVRALKQTGSRNIEAALEYISKMSYLD-PHTEQIVRVIKQTSPGKSGMPNLMDHRTAMEGSGDGALPPYHQMGAPLYEGASYGAEGEMARAYMGGP-PVMNYMPPPANPSQGATMGNPMGRPASMGAYSTNMAPQNNTGNPMYTPGPAQQKGYPSGIDQAMMGYSVSGPPMQIQSQPSGGPGAHYDYRSHMME---NSSYGVKRSASFQNKMPQLTTENYVNMPSKAAMGQN-AGGYAP----NLYLPPHSHPRQASPTSHQVHMMQRPPGVAPGAMGGEFSDVPQGLLTPSRASLNLDLYEH------HWPGAQGPEGTPPARQ----------PQGPFRGEVRVPSRTNSFNNHQKVTVRQTLPPTASVAGKPESSLGPPNTITAVTSPPIQPPVKSIRVMRPEPKTAVGPCHPGWLSAQ--SPE-----AQDSLGYIP--------DENFTLEPSQ---EHRCPPPPYPKTLLVSGSGPEPASLEPVAMSGLQDVSATG------RTIQSSSVGKQEESIFKDKVKMGKGEKAVKDKKQIQTSPVPVRK---NARDEEKRESRIKSYSPFAFKFYMEQHVENVMKTYQQKLNRRMQLEQEMSKAGLSEAEQEQMRKMLYQKESNYNRLRRAKMDKSMFVKIKTLGIGAFGEVCLTRKVDTG-ALYAMKTLRKKDVLNRNQVAHVKAERDILAEADNEWVVRLYYSFQDRDNLYFVMDYIPGGDMMSLLIRMGVFPEVLARFYVAELTLAIESVHKMGFIHRDIKPDNILIDLDGHIKLTDFGLCTGFRWTHNSKYYQK-GNHIRQDSMEPSDFWDDVSNCRCGDRLMTLEQRATRQHQRCLAHSLVGTPNYIAPEVLLRKGYTQLCDWWSVGVILFEMLVGQPPFLAPTPTETQLKVINWENTLQVPPQVKLSPEAVDIIGQLCCSAEERLGGNGAGEIKAHPFFSEVDFSSNLRTQPAPYRPKIAHPMDTSNFDPVEEEGGPGAWSDS-GDSTRTWDTLCSPHGKHPEHAFYEFTFRRFFDDNGCPFRYPKPLEATQSLSSSDGAGSLKPELEEEEAHEEEEQGEGCEPVYV", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VA38-1", "uniprot_id": "WARTS_DROME", "id": "Q9VA38-1", "name": "Serine/threonine-protein kinase Warts", "aln": "MHPAGEKRGGRPNDKYTAEALESIKQDLTRFEVQNNHRNNQNYTPLRYTATNGRNDALTPDYHHAKQPMEPPPSASPAPDVVIPPPPAIVGQPGAGSISVSGVGVGVVGVANGRVPKMMTALMPNKLIRKPSIERDTASSHYLRCSPALDSGAGSSRSDSPHSHHTHQPSSRTVGNPGGNGGFSPSPSGFSEVAPPAPPPRNPTACSAATPPP--PVPPTSQAYVKRRSPALNNRPPAIAP---------------PTQRGNSPVITQNG-----------LKNPQQQLTQQLKSLNLYP-------------GGGSG---AVVE--PPPPYLIQGGAGGAAPPPPPPS-YTASMQSRQSPTQSQQSDYRKSPSSGIYSATSAGSPSPITVSLPPAPLAKPQPRVYQARS------QQPIIMQSVKSTQVQKPVLQTAVAPQSPSSASASNSPVHVLAAPPSYPQKSAAVVQQQQQAAAAAHQQQHQHQQSKPPTPTTPPLVGLNSKPNCLEPPSYAKSMQAKAATVVQQQQQQQQQQQQVQQQQVQQQQQQQQQQLQALRVLQAQAQRERDQRERDQRERERDQQKLANGNPGRQMLPPPPYQSNNNNNSEIKPPSCNNNNIQISNSNLATTPPIPPAKYNNNSSNTG-ANSSGGSNGSTGTTASSSTSCKKIKHASPIPERKKISKEKEEERKEFRIRQYSPQAFKFFMEQHIENVIKSYRQRTYRKNQLEKEMHKVGLPDQTQIEMRKMLNQKESNYIRLKRAKMDKSMFVKLKPIGVGAFGEVTLVSKIDTSNHLYAMKTLRKADVLKRNQVAHVKAERDILAEADNNWVVKLYYSFQDKDNLYFVMDYIPGGDLMSLLIKLGIFEEELARFYIAEVTCAVDSVHKMGFIHRDIKPDNILIDRDGHIKLTDFGLCTGFRWTHNSKYYQENGNHSRQDSMEP---WEEYS--ENGPKPTVLERRRMRDHQRVLAHSLVGTPNYIAPEVLERSGYTQLCDYWSVGVILYEMLVGQPPFLANSPLETQQKVINWEKTLHIPPQAELSREATDLIRRLCASADKRLG-KSVDEVKSHDFFKGIDFA-DMRKQKAPYIPEIKHPTDTSNFDPVDPEK-----LRSNDSTMSSGDDVD--QNDRTFHGFFEFTFRRFFDDK-----------------------------------QPPDMTDDQAPVYV", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*:* . . : : *:.*::.*. : : : . . . . . : : :* :... . . ..: :: .. * ..* : * : * : * .: ..**: : . * *:..: : .:* . . ..:. . : .. : . . : : :: * . : *. : * . :: * :: ... * . .: :: . .:* . . : : * :: * * : : ..: . . . : .: :. . * .* .*. .:: : :. : : : :. : * . : ***** . . . . . :.: :* * : . .. . ..... ** ::**:* ** : ::**::* **:.*** ****:****:***:*:*:*: *: ***:** *.** : * :***:* ****** **:***********:*.:*:****** *. *:** ********* ***:*******************:***:*******:*.************:*****:: :* * *****:**:* *::******************** *************************: *.* ******* *:: * . * : .**:* ::*** ***************** *.*******:*******:*********** :* *** ******.**::*.*..** ** *:* :**.:*: *** ....::*:* **. :**: ::*.* *** * * ** ********: * : : : * : ..:. *.*:**********: : :. ****", "identical_positions": 353, "similar_positions": 242, "identity": "29.22%" }, { "cls_id": "homologset.agr.MGI:1354387", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9QZJ6-1", "uniprot_id": "MFAP5_MOUSE", "id": "Q9QZJ6-1", "name": "Microfibrillar-associated protein 5", "aln": "----------------------------------------------------------------------MLFLGQKALLLVLAISIPSDWLPLGVSGQRGDDV----PETFTDDPNLVNDPSTDDT---ALADITPSTDDLA--GDKNATAECRDEKFACTRLYSVHRPVRQCVHQSCFTSLRRMYIINNEICSRLVCKEHEAMKDELCRQMAGLPPRRLRRSNYFRLPPCENMNLQRPDGL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A0G2K9S8-1", "uniprot_id": "A0A0G2K9S8_RAT", "id": "A0A0G2K9S8-1", "name": "", "aln": "MSESSSFQCPYIGLQQKVWPKLKAKCEVFPRVWLCSSYSPAQVEQRKSQRRTDTLGSQRPRRTEHSAVDNMLVFGQKALLLVVALSIPSDWLPLGVSGQRGDDV----PETFTDDPNLVNDPSTDDT---VLADITPSTDDLASAGDKNTTAECRDEKFACTRLYSVHRPVRQCVHQACFTSLRRMYIINNEICSRLVCKEHEAMKDELCRQMAGLPPRRLRRSNYFRLPPCENMNLQRPDGP", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q13361-1", "uniprot_id": "MFAP5_HUMAN", "id": "Q13361-1", "name": "Microfibrillar-associated protein 5", "aln": "----------------------------------------------------------------------MSLLGPKVLLFLAAFIITSDWIPLGVNSQRGDDVTQATPETFTEDPNLVNDPATDETVLAVLADIAPSTDDLASLSEKNTTAECWDEKFTCTRLYSVHRPVKQCIHQLCFTSLRRMYIVNKEICSRLVCKEHEAMKDELCRQMAGLPPRRLRRSNYFRLPPCENVDLQRPNGL", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * .:* *.**:: *: *.***:****..****** *****:********:**:* .****:******* .:**:**** ****:***********:**:** **********:*:*******************************************::****:* ", "identical_positions": 131, "similar_positions": 26, "identity": "53.91%" }, { "cls_id": "homologset.agr.MGI:1354388", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9JLI7-1", "uniprot_id": "SPAG6_MOUSE", "id": "Q9JLI7-1", "name": "Sperm-associated antigen 6", "aln": "MSQRQVLQVFEQYQKARTQFVQMVAELATRPQNIETLQNAGVMSLLRPLLLDVVPTIQQTAALALGRLANYNDDLAEAVVKGDILPQLVYSLAEQNRFYKKAAAFVLRAVGKHSPQLAQAIVDCGALDTLVICLEDFDPGVKEAAAWALGYIARHNTELSQAVVDAGAIPLLVLCIQEPEIALKRIAASALSDISKHSPELAQTVVDAGAIAHLAQMILNPDAKLKRQVLSALSQIAKHSVDLAEMVVEAEIFPVVLTCLKDKDEYVKKNACTLIREIAKHTPELSQLIVNAGGVAAVIDCIGSCKGNIRLPGIMMLGYVAAHSENLAMAVIISKGVPQLSICLSEEPEDHIKAAAAWALGQLGRHTPEHARAVAVTNTLPVLLSLYMSPESSEDLQLKSKKAIKNILQKCTYLPALEPFLYDAPPNILKHVVGQFSKVLPHDSKARRLFVTSGGLKKVQEIKAEPGSLLQEYINSINNCYPEEIVRYYSPGYSDTLLQRVDSYQPL--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O75602-1", "uniprot_id": "SPAG6_HUMAN", "id": "O75602-1", "name": "Sperm-associated antigen 6", "aln": "MSQRQVLQVFEQYQKARTQFVQMVAELATRPQNIETLQNAGVMSLLRTLLLDVVPTIQQTAALALGRLANYNDDLAEAVVKCDILPQLVYSLAEQNRFYKKAAAFVLRAVGKHSPQLAQAIVDCGALDTLVICLEDFDPGVKEAAAWALRYIARHNAELSQAVVDAGAVPLLVLCIQEPEIALKRIAASALSDIAKHSPELAQTVVDAGAVAHLAQMILNPDAKLKHQILSALSQVSKHSVDLAEMVVEAEIFPVVLTCLKDKDEYVKKNASTLIREIAKHTPELSQLVVNAGGVAAVIDCIGSCKGNTRLPGIMMLGYVAAHSENLAMAVIISKGVPQLSVCLSEEPEDHIKAAAAWALGQIGRHTPEHARAVAVTNTLPVLLSLYMSTESSEDLQVKSKKAIKNILQKCTYLPALEPFLYDAPPNILKHVVGQFSKVLPHDSKARRLFVTSGGLKKVQEIKAEPGSLLQEYINSINSCYPEEIVRYYSPGYSDTLLQRVDSYQPLNN", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "***********************************************.********************************* ******************************************************************* ******:***********:*************************:***************:***************:*:******::**********************************.****************:******************* ********************************:********************:**************************.*******:********************************************************************************.**************************** ", "identical_positions": 488, "similar_positions": 16, "identity": "95.87%" }, { "cls_id": "homologset.agr.MGI:1354692", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9Y4Z0-1", "uniprot_id": "LSM4_HUMAN", "id": "Q9Y4Z0-1", "name": "U6 snRNA-associated Sm-like protein LSm4", "aln": "MLPLSLLKTAQNHPMLVELKNGETYNGHLVSCDNWMNINLREVICTSRD----------GDKFWRMPECYIRGSTIKYLRIPDEIIDMVKEEVV------AKGRG-------RGGLQQQKQQKGRGMGGAGRGVFGGRGRGGIPGTGRGQPEK------------KPGRQAGKQ-------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9QXA5-1", "uniprot_id": "LSM4_MOUSE", "id": "Q9QXA5-1", "name": "U6 snRNA-associated Sm-like protein LSm4", "aln": "MLPLSLLKTAQNHPMLVELKNGETYNGHLVSCDNWMNINLREVICTSRD----------GDKFWRMPECYIRGSTIKYLRIPDEIIDMVREEA-------AKGRG-------RGGPQQ-KQQKGRGMGGAGRGVFGGRGRGGIPGAGRGQPEK------------KPGRQAGKQ-------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8I6APJ0-1", "uniprot_id": "A0A8I6APJ0_RAT", "id": "A0A8I6APJ0-1", "name": "U6 snRNA-associated Sm-like protein LSm4", "aln": "-LPLSLLKTAQNHPMLVELKNGETYNGHLVSCDNWMNINLREVICTSRD----------GDKFWRMPECYIRGSTIKYLRIPDEIIDMVREEA-------AKGRG-------RGGPQQQKQQKGRGMGGAGRGRVTMRG-GRQASSEQSQPEL------------SPGRWVRRPPGAFA--------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9VKW8-1", "uniprot_id": "Q9VKW8_DROME", "id": "Q9VKW8-1", "name": "U6 snRNA-associated Sm-like protein LSm4", "aln": "MLPLSLLKTAQSHPMLVELKNGETYNGHLVSCDSWMNINLRDVICTSKD----------GDRFWRMPECYIRGSTIKYLRIPDEVIDMVKEDAQ------AKSRNRTEMNKNRGGNSSQNQRGGR-PGGGNRNNVGNRPGQGYGGAANNAMRLGG----------AAGQGNRLPHAAKNRK------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P40070-1", "uniprot_id": "LSM4_YEAST", "id": "P40070-1", "name": "LSM complex subunit LSM4", "aln": "MLPLYLLTNAKGQQMQIELKNGEIIQGILTNVDNWMNLTLSNVTEYSEESAINSEDNAESSKAVKLNEIYIRGTFIKFIKLQDNIIDKVKQQINSNNNSNSNGPGHKRYYNNRDSNNNRGNYNRRNNNNGNSNRRPYSQNRQYNNSNSSNINNSINSINSNNQNMNNGLGGSVQHHFNSSSPQKVEF", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *** **..*:.: * :****** :* *.. *.***:.* :* *.: ..: :: * ****: **:::: *::** *::: ::. . *.. .. : * .... . .: . . * ", "identical_positions": 36, "similar_positions": 48, "identity": "19.25%" }, { "cls_id": "homologset.agr.MGI:1354694", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9JL25-1", "uniprot_id": "RGS1_MOUSE", "id": "Q9JL25-1", "name": "Regulator of G protein signaling 1", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MRAAAISMPRLNKMPGMFFSASPKDSKEHSHSLLDDKKQKKRPKTFGMDVKTYLRSMIPHLESGMKSAKSKDILSAEEVMQWSQS----------------------LEKLLANQTGQNVFGRFLKSEFSEENIEFWLACEDYKKTETD------------------------------------LLHNKAENIYKAFVHSDAVKQINIDFHTRESTAKKIKTPTP----------------------------------------------------------------------------------------------------------------------TSFDEAQKVIYSLMEKDSYPRFLKSNIYLNLLNDLQANTLK", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P97844-1", "uniprot_id": "RGS1_RAT", "id": "P97844-1", "name": "Regulator of G protein signaling 1", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MRAAAISMPRLNKMPGMFFSASPKDSKEPSHSLLDDNKQKKRPKTFGMDMKAYLRSMIPHLESGMKSSKSKDILSAEEVMQWSQS----------------------LEKLLANQMGQNVFGKFLKSEFSEENIEFWLACEDYKKTETD------------------------------------LLHNKAEHIYKAFVHSDAVKQINIDFHTRESTAKKIKTPTP----------------------------------------------------------------------------------------------------------------------TCFDEAQKVIYALMEKDSYPRFLKSNIYLNLLNDLQANTLK", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q08116-1", "uniprot_id": "RGS1_HUMAN", "id": "Q08116-1", "name": "Regulator of G protein signaling 1", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MRAAAISTPKLDKMPGMFFSANPKELKGTTHSLLDDKMQKRRPKTFGMDMKAYLRSMIPHLESGMKSSKSKDVLSAAEVMQWSQS----------------------LEKLLANQTGQNVFGSFLKSEFSEENIEFWLACEDYKKTESD------------------------------------LLPCKAEEIYKAFVHSDAAKQINIDFRTRESTAKKIKAPTP----------------------------------------------------------------------------------------------------------------------TCFDEAQKVIYTLMEKDSYPRFLKSDIYLNLLNDLQANSLK", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9PSS8-1", "uniprot_id": "A0A8M9PSS8_DANRE", "id": "A0A8M9PSS8-1", "name": "Regulator of G-protein signaling 1", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MLISMCSIHASKRVRTLQSHKEPPSEAETHAEDTAD---------RDGHKEP-------VDDVDSWGES----------------------IEKLLSCKAGQAAFQDFLKSEYSEENILFWLACEEYKKVTNEP-----------------------------------EMISMANQIYTEFVQTEAPRQVNIDSGTRTNITNSISEPTR----------------------------------------------------------------------------------------------------------------------SSFDTAQKMIFSLMTRDCYPRFLKSDIYQSILQKHGKR---", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P11972-1", "uniprot_id": "SST2_YEAST", "id": "P11972-1", "name": "Protein SST2", "aln": "MVDKNRTLHELSSKNFSRTPNGLIFTNDLKTVYSIFLICLDLKEKKHSSDTKSFLLTAFTKHFHFTFTYQEAIKAMGQLELKVDMNTTCINVSYNIKPSLARHLLTLFMSSKLLHTPQDRTRGEPKEKVLFQPTPKGVAVLQKYVRDIGLKTMPDILLSSFNSMKLFTFERSSVTDSIIHSDYLIHILFIKMMGAKPNVWSPTNADDPLPCLSSLLEYTNNDDTFTFEKSKPEQGWQAQIGNIDINDLERVSPLAHRFFTNPDSESHTQYYVSNAGIRLFENKTFGTSKKIVIKYTFTTKAIWQWIMDCTDIMHVKEAVSLAALFLKTGLIVPVLLQPSRTDKKKFQISRSSFFTLSKRGWDLVSWTGCKSNNIRAPNGSTIDLDFTLRGHMTVRDEKKTLDDSEGFSQDMLISSSNLNKLDYVLTDPGMRYLFRRHLEKELCVENLDVFIEIKRFLKKMTILKKLIDSKHCDKKSNTSTSKNNIVKTIDSALMKQANECLEMAYHIYSSYIMIGSPYQLNIHHNLRQNISDIMLHPHSPLSEHFPTNLYDPSPASAESAASSISSTEADTLGEPPEVSLKPSKNLSNENCSFKKQGFKHQLKEYKPAPLTLAETHSPNASVENSHTIVRYGMDNTQNDTKSVESFPATLKVLRKLYPLFEIVSNEMYRLMNNDSFQKFTQSDVYKDASALIEIQEKC", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ::.. :.: . .. . * . .. .: .:. :: :*: : * .*:.* . **: .:: : : * . * .**. :: : *:**. * . :. : * . *: ..: :: ** .*.: :* :*::* . . ", "identical_positions": 23, "similar_positions": 62, "identity": "3.3%" }, { "cls_id": "homologset.agr.MGI:1354695", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3Z902-1", "uniprot_id": "FBXW7_RAT", "id": "D3Z902-1", "name": "F-box/WD repeat-containing protein 7", "aln": "----------------------------------------------------------------------------------------------------------------------------MNQELLSVGS---------KRRRTGGSLRGNASS---SQVDEEQMNRVVEEDPQQQPRHQEEEHTARNGELVGADPRP-GAQNDSQQG--QVEENNNRFVS---VDEDS--------SGNQ---------------EEQEEDEE--------------------------------------------------------HAGEQEEEEEE--EEEEEEEEEMDQESDDFDQSDDSSREDEHT------------------------------------------------HNSNVTNCTSVVDLPINQLSS---PFYTKT----TKMKRKLDHGS-----------------------------------------------------------------------EVRSFSLGKKPCKVSDYTSTTGLVPCSATPT---------------------------------------------------TFGDLRAANGQG--------------------------------------------------------------------------------------------------------------------------QQRRR-----------------------------------------------------------------ITSVQP------------------PTGLQEWLKMFQSWSGPEKLLALDELIDSCEPTQVKHMMQVIEPQFQRDFISLLPKELALYVLSFLEPKDLLQAAQTCRYW-RILAEDNLLWREKCKEEGIDEPLHIKRR--KIIKPG---FIHSPWKSAYIRQHRIDTNWRRGELRSPK-VLKGHDDHVITCLQFCGNRIVSGSDDNTLKVWSAVTGKCLRTLVGHTGGVWSSQMRDN-IIISGSTDRTLKVWNAETGECIHTLYGHTSTVRCMHLHEKR----VVSGSRDATLRVWDIETGQ-----------------------CLHVLMGHVAAVRCVQYDGRRVVSGAYDFMVKVWDPETETCLHTLQGHTNRVYSLQFDG--IHVVSGSLDTSIRVWDVETGN--------------------CIHTLTGHQSLTSGMELKDNILVSGNADSTVKIWDIKTGQCLQTLQGPSKHQSAVTCLQFNKNFVITSSDDGTVKLWDLKTGEFIRNLVTLESGGSGGVVWR------------------IRASNTKLVCAVGSRNGTEETKLLVLDFDVDMK------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8VBV4-2", "uniprot_id": "FBXW7_MOUSE", "id": "Q8VBV4-2", "name": "F-box/WD repeat-containing protein 7", "aln": "----------------------------------------------------------------------------------------------------------------------------MNQELLSVGS---------KRRRTGGSLRGNASS---SQVDEGQMNRVVEEDPQQQARHQEEEHTARNGELVGANPRP-GDQNDTQQG--QVEENNNRFIS---VDEDS--------SGNQ---------------EEQEEDEE--------------------------------------------------------HAGEQEEEEEE--EEEEEE---MDQESDDFDPSDDSSREDEHT------------------------------------------------HNSNVTNCSSVSDLPAHQLSS---PFYTKT----TKMKRKLDHGS-----------------------------------------------------------------------EVRSFSLGKKPCKVSDYTSTTGLVPCSATPT---------------------------------------------------TFGDLRAANGQG--------------------------------------------------------------------------------------------------------------------------QQRRR-----------------------------------------------------------------ITSVQP------------------PTGLQEWLKMFQSWSGPEKLLALDELIDSCEPTQVKHMMQVIEPQFQRDFISLLPKELALYVLSFLEPKDLLQAAQTCRYW-RILAEDNLLWREKCKEEGIDEPLHIKRR--KIIKPG---FIHSPWKSAYIRQHRIDTNWRRGELKSPK-VLKGHDDHVITCLQFCGNRIVSGSDDNTLKVWSAVTGKCLRTLVGHTGGVWSSQMRDN-IIISGSTDRTLKVWNAETGECIHTLYGHTSTVRCMHLHEKR----VVSGSRDATLRVWDIETGQ-----------------------CLHVLMGHVAAVRCVQYDGRRVVSGAYDFMVKVWDPETETCLHTLQGHTNRVYSLQFDG--IHVVSGSLDTSIRVWDVETGN--------------------CIHTLTGHQSLTSGMELKDNILVSGNADSTVKIWDIKTGQCLQTLQGPSKHQSAVTCLQFNKNFVITSSDDGTVKLWDLKTGEFIRNLVTLESGGSGGVVWR------------------IRASNTKLVCAVGSRNGTEETKLLVLDFDVDMK------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q969H0-1", "uniprot_id": "FBXW7_HUMAN", "id": "Q969H0-1", "name": "F-box/WD repeat-containing protein 7", "aln": "----------------------------------------------------------------------------------------------------------------------------MNQELLSVGS---------KRRRTGGSLRGNPSS---SQVDEEQMNRVVEEEQQQQLRQQEEEHTARNGEVVGVEPRP-GGQNDSQQG--QLEENNNRFIS---VDEDS--------SGNQ---------------EEQEEDEE--------------------------------------------------------HAGEQDEEDEE--EEE------MDQESDDFDQSDDSSREDEHT------------------------------------------------HTNSVTNSSSIVDLPVHQLSS---PFYTKT----TKMKRKLDHGS-----------------------------------------------------------------------EVRSFSLGKKPCKVSEYTSTTGLVPCSATPT---------------------------------------------------TFGDLRAANGQG--------------------------------------------------------------------------------------------------------------------------QQRRR-----------------------------------------------------------------ITSVQP------------------PTGLQEWLKMFQSWSGPEKLLALDELIDSCEPTQVKHMMQVIEPQFQRDFISLLPKELALYVLSFLEPKDLLQAAQTCRYW-RILAEDNLLWREKCKEEGIDEPLHIKRR--KVIKPG---FIHSPWKSAYIRQHRIDTNWRRGELKSPK-VLKGHDDHVITCLQFCGNRIVSGSDDNTLKVWSAVTGKCLRTLVGHTGGVWSSQMRDN-IIISGSTDRTLKVWNAETGECIHTLYGHTSTVRCMHLHEKR----VVSGSRDATLRVWDIETGQ-----------------------CLHVLMGHVAAVRCVQYDGRRVVSGAYDFMVKVWDPETETCLHTLQGHTNRVYSLQFDG--IHVVSGSLDTSIRVWDVETGN--------------------CIHTLTGHQSLTSGMELKDNILVSGNADSTVKIWDIKTGQCLQTLQGPNKHQSAVTCLQFNKNFVITSSDDGTVKLWDLKTGEFIRNLVTLESGGSGGVVWR------------------IRASNTKLVCAVGSRNGTEETKLLVLDFDVDMK------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9PIU0-1", "uniprot_id": "A0A8M9PIU0_DANRE", "id": "A0A8M9PIU0-1", "name": "F-box/WD repeat-containing protein 7", "aln": "MSRSMCGCGCSFISSLMKRLGRSACCSD-----------------------------------LLSCSHTSEHLQRLATGCPSQH---------------KNAKSLSSSDSLAKVQEVASWLLEMNQDLLSGGSGSR--AAQQQRPRPGTAGAGNSISGRTPQPQPEHPDQVLEEPEQEEAQQQRREPAEEEDEGGPERQQD-GDEQPWPSGGEPMEDGEGRRSE---VNGDE--------KGAQWLWEQEQRRRRRPHREEEEENEEEEEN-------------------------------------------NNSGREGQVGAGLRSEEDDDRPEEDNEGEEEMDQDSDEFEHSEESEREEEEEDGEEE-------------------------------------EGEEGLHSPSLRTSVSDHNDNTDQSSGRQRQSLRSP----NRMKRKLDHGP-----------------------------------------------------------------------EVRSFTTGKKPCP-----SPTG----QQYPA---------------------------------------------------TFGDLRAVNGQV--------------------------------------------------------------------------------------------------------------------------PQRRR-----------------------------------------------------------------ITSIQP------------------PTGLQEWLRTFQSWSGPEKLLALDELIDSCEPTQVKHMMQVIEPQFQRDFISLLPRELALHVLSFLEPKDLLQAAQTCRYW-RILAEDNLLWKEKCKEEGIDEPLHIKRR--KVIKPG---FTHSPWKSAYIRQHRIDTNWRRGDLKSPKVVLKGHDDHVITCLQFCGNRIVSGSDDNTLKVWSAVTGKCLRTLVGHTGGVWSSQMRDN-IIISGSTDRTLKVWNAETGECIHTLYGHTSTVRCMHLHEKR----VVSGSRDATLRVWDIETGQ-----------------------CLHVLMGHVAAVRCVQYDGRRVVSGAYDFMVKVWDPETETCLHTLQGHTNRVYSLQFDG--IHVVSGSLDTSIRVWDVETGN--------------------CIHTLTGHQSLTSGMELKDNILVSGNADSTVKIWDIKTGQCLQTLQGPHKHQSAVTCLQFNKNFVITSSDDGTVKLWDLRTGEFIRNLVTLESGGSGGVVWR------------------IRASNTKLVCAVGSRNGTEETKLLVLDFDVDMK------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VZF4-1", "uniprot_id": "FBXW7_DROME", "id": "Q9VZF4-1", "name": "F-box/WD repeat-containing protein 7", "aln": "MERGCPAASSESVTSAGERTQSAVTSSTSTWVKSQASTSRKTEASEESGLGAVDAEVGAGREAFVSMSTLREDVEDVCVSSNSQHGFAVVLDDESSTFEISSSNSLPTSAGAASTVGVVAVDDSSSTDTLNGGHPDLGHPASSEHSRQGFFNEDNEDPPVVCLINDDDDDEEPEPEEDDEEELIEDEDEDAVDIVTGAISCPNTSQLALADGTIMAADGSKIFLETPVVEEAQPHPGQVVTTGSQSELTGKPKRLSDEFLLGEEDQAENLALGRCIKSEPVNPVDDNPSEGDDGATCFSLHDRLMSVRLKQMSLTANTVSNPSPAASANAAAPEEASTSNSSSTSSSALSRADIESMDLIERRDFETEQRLTGGIILRTSSMVSQNKLNLSLIKSMAGGSKAANGSGTANSDDWPSSSNGRTVSSDSKYTYKDLSTTPTSSRKYTNSRLSKSTAKLNLGSSLGASSCSQHRSGSSSTSKSMESSTSCTGAARTDVYTNTNSNDYPSLAPTTSGSSTSGGSCQQDQEENVSASVSYSSVGSQTSQESGCSRTTAINPTAACSTGSACLGDSQASTSASTSSGAGASNRCQYATTSTTKAARQVNASAQTQERFLTRSNPPAASGAGSVGANPTASVRQRRNGSSDVVHLEVVVEEGAGGGDGGVVEPGDFSAEEPWANCDEENNCSDLEEICTCQNGNGSSYGGSNASLSETFDMDAMDPDEPISLSLSSASAGFTEYSLTNPSSLMSHQRKRKFNEGRLLDGGDYSVTISSSGEVGGPGSGVSDNCRKRIAYDFASTPRSSQHLGPTAVLSVTPSSHLTSSTPGSALGRRTPRSVPSRDNPPPELQHWLAQFQRWSHVERLLALDRLIDHCDPSQVRHMMKVIEPQFQRDFISLLPRELALFVLSYLEPKDLLRAAQTCRSW-RFLCDDNLLWKEKCRKAQILAEPRSDRP--KRGRDGNMPPIASPWKAAYMRQHIIEMNWRSRPVRKPK-VLKGHDDHVITCLQFSGNRIVSGSDDNTLKVWSAVNGKCLRTLVGHTGGVWSSQMSGN-IIISGSTDRTLKVWDMDSGACVHTLQGHTSTVRCMHLHGSK----VVSGSRDATLRVWDIEQGS-----------------------CLHVLVGHLAAVRCVQYDGKLIVSGAYDYMVKIWHPERQECLHTLQGHTNRVYSLQFDG--LHVVSGSLDTSIRVWDVETGN--------------------CKHTLMGHQSLTSGMELRQNILVSGNADSTVKVWDITTGQCLQTLSGPNKHHSAVTCLQFNSRFVVTSSDDGTVKLWDVKTGDFIRNLVALDSGGSGGVVWR------------------IRANDTKLICAVGSRNGTEETKLMVLDFDVEGACVKCS-", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P07834-1", "uniprot_id": "CDC4_YEAST", "id": "P07834-1", "name": "Cell division control protein 4", "aln": "-------------------------------------------------------------------------------------------------------------------MGSFPLAEFPLRDIPVPYS----------YRVSGGIASSGSVTALVTAAGTHRNSSTAKTVETEDGEEDIDEYQRKRAAGSGESTPERSDFKR------VKHDNHKTLHP---VNLQN--------TG--------------------------------------------------------------------------------AASVDNDGLHNLTDISNDAEKLLMSVDDGSAAPSTLSVNMGVAS------------------------------------------------HNVAAPTTVNAATITGSDVSN-----NVNS----ATINNPMEEGA------------------------------------------------------------------------LPLSPTASSPGTTTPLAKTTKTINNNNNIA------------------------------------------------------DLIES--KD-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SIISP-----------------EYLSDEIFSAINNNLPHAYFKNLLFRLVANMDRSELSDLGTLIKDNLKRDLITSLPFEISLKIFNYLQFEDIINSLGVSQNWNKIIRKSTSLWKKLLISENFVSPKGFNSLNLKLSQKYPKLSQQDRLRLSFLENIFILKNWYNPKFVPQRTTLRGHMTSVITCLQFEDNYVITGADDKMIRVYDSINKKFLLQLSGHDGGVWALKYAHGGILVSGSTDRTVRVWDIKKGCCTHVFKGHNSTVRCLDIVEYKNIKYIVTGSRDNTLHVWKLPKESSVPDHGEEHDYPLVFHTPEENPYFVGVLRGHMASVRTVSGHGNIVVSGSYDNTLIVWDVAQMKCLYILSGHTDRIYSTIYDHERKRCISASMDTTIRIWDLENIWNNGECSYATNSASPCAKILGAMYTLQGHTALVGLLRLSDKFLVSAAADGSIRGWDAN--DYSRKFSYHHTNLSAITTFYVSDNILVSGSEN-QFNIYNLRSGKLVHANILKDADQIWSVNFKGKTLVAAVEKDGQSFLEILDFSKASKINYVSNPVNSSSSSLESISTSLGLTRTTIIP", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : * .. . . : :: . * :. *: . .* : . : .: . . . . . . : * . . :: *. : . .... .* : : : * : : : . * .*: : ::: .: :*: :::**:*: ** *::* ::.:*: :*::.: ..: * ::: ... **:: . : . * : . : :::.: * ** . : .*:** ******* .* :::*:**: ::*:.::. * * * ** ****: : . *::*******::**: ..* * *.: **.*****:.: : :*:**** **:**.: . : ** **:*:** *. .*. :***:** : :*. **: *.***:*:** :* : :*.*:**:**:**:*. . :** ** :*.. :.* :::***. **.::: ** . : :.:. .: **:* : ....::::.*:: .:::::::*.::: : ::. .* :: : ..:. : *.. .:..:.* :. .: ", "identical_positions": 135, "similar_positions": 231, "identity": "9.65%" }, { "cls_id": "homologset.agr.MGI:1354696", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9QZN3-1", "uniprot_id": "FBX8_MOUSE", "id": "Q9QZN3-1", "name": "F-box only protein 8", "aln": "MGQGLWRVARNHHLQQEAYSETGYLSREQSRRVASSNISHTSHRKQAQGGIDIYHLLKARKSKEQEGFINLEMLPPELSFTILSYLNATDLCLASCVWQDLANDELLWQGLCKSTWGHCSIYNKNPPLGFSFRKLYMQLDEGSLTFNANPEEGVSYFMSKGILDDSPKEIAKFIFCTRTLNWKKLRIYLDERRDVLDDLVTLHNFRNQFLPNALREFFRHIHAPEERGEYLETLITKFSHRFCACNPDLMRELGLSPDAVYVLCYSLILLSIDLTSPHVKNKMSKREFIRNTRRAAQNISEDFVGHLYDNIYLIGHVAA", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q5M7U1-1", "uniprot_id": "Q5M7U1_RAT", "id": "Q5M7U1-1", "name": "F-box only protein 8", "aln": "MGQGLWRVARNQHLQQEAYGETGYLSREQSRRVASSNISHTSHRKQAQGGIDIYHLLKARKSKEQEGFINLEMLPPELSFTILSYLNATDLCLASCVWQDLANDELLWQGLCKSTWGHCSIYNKNPPLGFSFRKLYMQLDEGSLTFNANPEEGVSYFMSKGILDDSPKEIAKFIFCTRTLNWKKLRIYLDERRDVLDDLVTLHNFRNQFLPNALREFFRHIHAPEERGEYLETLITKFSHRFCACNPDLMRELGLSPDAVYVLCYSLILLSIDLTSPHVKNKMSKREFIRNTRRAAQNISEDFVGHLYDNIYLIGHVAA", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9NRD0-1", "uniprot_id": "FBX8_HUMAN", "id": "Q9NRD0-1", "name": "F-box only protein 8", "aln": "MGQGLWRVVRNQQLQQEGYSEQGYLTREQSRRMAASNISNTNHRKQVQGGIDIYHLLKARKSKEQEGFINLEMLPPELSFTILSYLNATDLCLASCVWQDLANDELLWQGLCKSTWGHCSIYNKNPPLGFSFRKLYMQLDEGSLTFNANPDEGVNYFMSKGILDDSPKEIAKFIFCTRTLNWKKLRIYLDERRDVLDDLVTLHNFRNQFLPNALREFFRHIHAPEERGEYLETLITKFSHRFCACNPDLMRELGLSPDAVYVLCYSLILLSIDLTSPHVKNKMSKREFIRNTRRAAQNISEDFVGHLYDNIYLIGHVAA", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "********.**::****.*.* ***:******:*:****:*.****.*******************************************************************************************************:***.********************************************************************************************************************************************************************", "identical_positions": 305, "similar_positions": 13, "identity": "95.61%" }, { "cls_id": "homologset.agr.MGI:1354697", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZYT9-1", "uniprot_id": "D3ZYT9_RAT", "id": "D3ZYT9-1", "name": "F-box/LRR-repeat protein 8", "aln": "MVELIEKLPEEVLGLIFRDLPLRDRAVAARVCRAWAAAATNSAVWYDTSISCDCELENLLPPGLSACLDHIHNLSLEYEPSKKPSRRTATELLTALASRAPRLRGLRLECRGEKPLFDAGRDILGALHTVCGAAHQLRHLDLRHLPYTVDDTLVLKVAGGCPELRSLFLDNHALVNSVQPASVLRLLEACPHLRALGLHLASMSRAALELLAAPHRAPFTLLALKCACPEDARASPLPDEAWATLTCYHPGLKVELELEPVLPDEAVSRILQPAVPVAVLRLNLSGDTVGPVRFAARHYAETLRALEVRASASTELHTALEELAARCAGLREIHCFCVVRPSVLDAFRAHCPRLRSYTLKLKREPHPWRPTLMR", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8CIG9-1", "uniprot_id": "FBXL8_MOUSE", "id": "Q8CIG9-1", "name": "F-box/LRR-repeat protein 8", "aln": "MGELVDNLPEEVLALIFRDLPLRDLAVATRVCRAWAAAAANSTVWSDKSISCDCELEDLLPPYLSSCLDHIHNLRLEYEPSKKPSRGTATELLTALASRAPRLRGLRLECRGEKPLFDAGQDILGAVHAVCGAAHQLRHLDLRHLPYTLDDTLVLKAAAGCPELRSLFLDNHALVNSVQPTSVLKLLEACPHLRALGLHLASMSRAALELLAAPHRSPFALLALRCACPEDARASPLPDEAWATLSCRHPGLEVELELEPVLPDEAVTRILQPAVPVAVLRLNLSGDTVGPVRFATRHYAETLRALEVRASASPELHTALEELAARCAGLREIHCFCVVRPSVLDAFRAHCPRLRSYTLKLKREPHPWRPTLVR", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q96CD0-1", "uniprot_id": "FBXL8_HUMAN", "id": "Q96CD0-1", "name": "F-box/LRR-repeat protein 8", "aln": "MAEPGEGLPEEVLALIFRHLSLRDRAAAARVCRAWAAAATCSAVWHDTKISCECELEGMLPPYLSACLDHIHNLRLEFEPSRKPSRRAAIELLMVLAGRAPGLRGLRLECRGEKPLFDAGRDVLEAVHAVCGAASQLRHLDLRRLSFTLDDALVLQAARSCPELHSLFLDNSTLVGSVGPGSVLELLEACPRLRALGLHLASLSHAILEALAAPDRAPFALLALRCACPEDARASPLPNEAWVALRRRHPGLAVELELEPALPAESVTRVLQPAVPVAALRLNLSGDTVGPVRFAAHHYAATLCALEVRAAASAELNAALEELAARCAALREVHCFCVVSHSVLDAFRAHCPRLRTYTLKLTREPHPWRPTLVA", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* * : ******.****.*.*** *.*:**********: *:** *..***:****.:*** **:******** **:***:**** :* *** .**.*** ******************:*:* *:*:***** ********:*.:*:**:***:.* .****:****** :**.** * ***.******:**********:*:* ** ****.*:**:****:*************:***.:* **** *******.** *:*:*:********.****************::*** ** ******:**.**::**********.***:****** **************:*****.**********: ", "identical_positions": 282, "similar_positions": 61, "identity": "75.4%" }, { "cls_id": "homologset.agr.MGI:1354698", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9JMJ2-1", "uniprot_id": "FBXW4_MOUSE", "id": "Q9JMJ2-1", "name": "F-box/WD repeat-containing protein 4", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MAEDAAEDAAAAAVEPATRPAAGPALWRLPEELLLLICSYLDTRALGRLAQVCRWLRRFTSCDLLWRPIARASLNTGFTRLGTDLMAGIPVKERVKLSQNWRLGRCRDRILLKWRYSQMPWMQLQDASLYLSQANFILAYQFRPDGASLNRRPFRVFSGHDEDVCHFVLANSHIVSAGGDGKIGVHKIHSTFTVKYSAHEQEVNCVDCKGGIIVSGSRDRTAKVWPLASGRLGQCLHTIQTEDRVWSIAISPLLSSFVTGTACCGHFSPLRIWDLNSGQLITHLGSDFPPGAGVLDVMYESPSTLLSCGYDTYVRYWDLRTSTRKCVMEWEEPHDSTFYCLQTDGNHLLATGSSYYGLVRLWDRRQRACLHAFSLTSTPLSSPVYCLRFTTRHLYAALSYNLHVLDFQNP", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D4A2V7-1", "uniprot_id": "D4A2V7_RAT", "id": "D4A2V7-1", "name": "F-box/WD repeat-containing protein 4", "aln": "MTCFNQMFLVLQKMGMSAPRLGFAPRKTGVRGGSRLGPAPPHVTRSVVMSPPLEEAVASSAPLCVEPARRPLMSSQGRSGPPGNRGPREGEGGEARKLQEARVARGKRGKGKGKASTGHGGRGSGAEGKPGLQPARKAAGPAAEAGRGQEGEGGEEEGPRRSGRQDEGSAEPGKEECRVGAGRREDHSLERAQEQERQACGGIPETQTAMAAAAEDGAAAVEPATRPAAGPALWRLPEELLLLICSYLDMRALGRLAQVCRWLRRFTSCDLLWRPIARASLNSGFTRLGTDLMTSIPVKERVKLSQNWRLGRCRDRILLKWRYSQMPWMQLEDSSLYLSQANFILAYQFRPDGASLNRRPFRVFAGHDEDVCHFVLANSHIISAGGDGKIGVHKIHSTFTVKYSAHEQEVNCVDCKGGIIVSGSRDRTAKVWPLASGQLGQCLHTIQTEDRVWSIAISPVLSSFVTGTACCGHFSPLRIWDLTSGQLITHLGSDFPPGAGVLDVMYESPSTLLSCGYDTYVRYWDLRTSARKCVMEWEEPHDSTFYCLQTDGNHLLATGSSYYGLVRLWDRRQRACLHAFPLTSTPLSSPVYCLRFTTRHLYAALSYNLHVLDFENP", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P57775-1", "uniprot_id": "FBXW4_HUMAN", "id": "P57775-1", "name": "F-box/WD repeat-containing protein 4", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MAAAAGEEEEEEEAARESAARPAAGPALWRLPEELLLLICSYLDMRALGRLAQVCRWLRRFTSCDLLWRRIARASLNSGFTRLGTDLMTSVPVKERVKVSQNWRLGRCREGILLKWRCSQMPWMQLEDDSLYISQANFILAYQFRPDGASLNRRPLGVFAGHDEDVCHFVLANSHIVSAGGDGKIGIHKIHSTFTVKYSAHEQEVNCVDCKGGIIVSGSRDRTAKVWPLASGRLGQCLHTIQTEDRVWSIAISPLLSSFVTGTACCGHFSPLRIWDLNSGQLMTHLGSDFPPGAGVLDVMYESPFTLLSCGYDTYVRYWDLRTSVRKCVMEWEEPHDSTLYCLQTDGNHLLATGSSYYGVVRLWDRRQRACLHAFPLTSTPLSSPVYCLRLTTKHLYAALSYNLHVLDFQNP", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * : ** *.*:************************ ************************ *******:**********:.:*******:**********: ****** ********:* ***:**********************: **:****************:*********:*********************************************:*********************:**********************.****:********************* *******************.**************:*******************:***************.**************:**:***************:**", "identical_positions": 367, "similar_positions": 26, "identity": "59.48%" }, { "cls_id": "homologset.agr.MGI:1354699", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0ABK0L5N1-1", "uniprot_id": "A0ABK0L5N1_RAT", "id": "A0ABK0L5N1-1", "name": "F-box DNA helicase 1", "aln": "--------------MRRFKRKHLTVVDCQQLARS---HLAATQPFSQRWTNRDPNHGLYPRARTKGRNRGRGCQRYISEFFLASHQHCTNDMAKSNSVGQDSCQDSENDMIFPAESSCSLPQVENGEVRLGSPGSAQPARKRPRSLEEATE----SGQWDGVTKKTPRHRLFPSCARLREVRQGAEDGLSQSSPVHGEAAQDIEDIGPDPLPDSYYGLLGTLPCQEVPS-HICRLPSEVLRHIFAFLPVEDLYWNLSLVCHLWREIVNDPLFIPWKKLYHRYLINEEQAVSKVDGILSSHGIEKDSDLCVLNLIRYTATTKCSPSVDPERVLWSLRDHPLLLEAEACMRQQLPDLYAAAGGINVWALVAAMVLLSSCVNDIQHLLFCLRRPRSTVTMPDVTETLYCIAVLLYAMREKGINISNRIHYNIFYCLYLQENSCTQATKVTEEPSVWPGKKTSIQLTHEQQLILNHKMEPLQVVKIMAFAGTGKTSTLVKYAEKWSQSRFLYVTFNKSIAKQAELVFPSNVICKTFHSMAYSHVGRKYQLKKKLNLFKLTPFMVNSVLAEGKGGFIRAKLVCKTLENFFASADEELTIDHVPIWCKNSQGQRVMVEQSEKLNGVLEASRLWDNMRKLGECKEEAYQMTHDGYLKLWQLSKPLLASFDAIFVDEAQDCTPAIMNIVLSQPCGKIFVGDPHQQIYTFRGAVNALFTVPHTHVFYLTQSFRFGVEIAYVGATILDVCKRVRKKTLVGGNHQSGIRGD--------------VKGQVALLSRTNANVFDEAVRVTEGESPARIHLIGGIKSFGLDRIIDIWTLLQPEEERRKRDLIIKDRFIRRWVHKEG--FSGFKRYVTAAEDKELEAKIAVVEKYNVRIPELVERIERCHIEDLDFAEYILGTVHKAKGLEFDTVHVLDDFVKVPCARHNLGQLPHFRVESFSEDEWNLLYVAVTRAKKRLIMTKSLENILTLAGEYFLQAELTSNVLKTG-VVHCCVGQCNNTIPVDTILTMRKLPITYSNRKENKGGYLCHSCAEQRIGPLAFLTASPEQVRAMERTVEDLVLPRHEALLFLVF-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8K2I9-1", "uniprot_id": "FBH1_MOUSE", "id": "Q8K2I9-1", "name": "F-box DNA helicase 1", "aln": "--------------MRRFKRKHLTVVDCHHLARS---HLAVTQPFSQRWTNRDPNHGLYPRPRTKGRNRGRGCQRYISEFFLAGHQHCTNDMAKSNSVGQDSCQDAEGDMILTAESSCTLPQVDNGEARLGSSGSAQPARKRAHCFEEATE----SGQWDGVTKKTPRHRLFPSCSRLREARQGAEDSLSQCSPVPGEAGRDIEDIGPDPLPDSYYGLLGMLPCQEVPS-HICRLPSEVLRHIFAFLPVEDLYWNLSLVCHLWREIINDPLFIPWKKLYHRYLINEEQAVSKVDGILSSHGIEKDSDLCVLNLIRYTATTKCSPSVDPERVLWSLRDHPLLLEAEACMRQQLPDLYAAAGGINVWALVAAMVLLSSCVNDIQHLLFCLRRPSSTVTMPDVTETLYCIAVLLYAMREKGINISNRIHYNIFYCLYLQENSCTQATKVTEEPSVWPGKKTSIQLTHEQQLILNHKMEPLQVVKIMAFAGTGKTSTLVKYAEKWSQSRFLYVTFNKSIAKQAELVFPSNVICKTFHSMAYSHVGRKYQLKKKLNLFKLTPFMVNSVLAEGKGGFIRAKLVCKTLENFFASADEELTIDHVPIWCKNSHGQRVMVEQSEKLNGVLEASRLWDNMRKLGECKEEAYQMTHDGYLKLWQLSKPLLASFDAIFVDEAQDCTPAIMNIVLSQPCGKIFVGDPHQQIYTFRGAVNALFTVPHTHVFYLTQSFRFGVEIAYVGATILDVCKRVRKKTLVGGNHQSGIRGD--------------IKGQVALLSRTNANVFDEAVRVTEGESPARIHLIGGIKSFGLDRIIDIWTLLQPEEERRKRDLIIKDRFIRRWVHKEG--FSGFKRYVTAAEDKELEAKIAVVEKYNIRIPELVERIERCHIDDLDFAEYILGTVHKAKGLEFDTVHVLDDFVKVPCARHNLAQLPHFRVESFSEDEWNLLYVAVTRAKKRLIMTKSLENILTLAGEYFLQAELTSNVLKTG-VVHCCVGQCNNTIPVDTILTMKKLPITYSNRKENKGGYLCHSCAEQRIGPLAFLTASPEQVRAMERTVEDIVLPRQEALLFLVF-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8NFZ0-1", "uniprot_id": "FBH1_HUMAN", "id": "Q8NFZ0-1", "name": "F-box DNA helicase 1", "aln": "--------------MRRFKRKHLTAIDCQHLARS---HLAVTQPFGQRWTNRDPNHGLYPKPRTKRGSRGQGSQRCIPEFFLAGKQPCTNDMAKSNSVGQDSCQDSEGDMIFPAESSCALPQE--GSAGPGSPGSAPPSRKRSWSSEEESNQATGTSRWDGVSKKAPRHHLSVPCTRPREARQEAEDSTSRLSAESGETDQDAGDVGPDPIPDSYYGLLGTLPCQEALS-HICSLPSEVLRHVFAFLPVEDLYWNLSLVCHLWREIISDPLFIPWKKLYHRYLMNEEQAVSKVDGILSNCGIEKESDLCVLNLIRYTATTKCSPSVDPERVLWSLRDHPLLPEAEACVRQHLPDLYAAAGGVNIWALVAAVVLLSSSVNDIQRLLFCLRRPSSTVTMPDVTETLYCIAVLLYAMREKGINISNRIHYNIFYCLYLQENSCTQATKVKEEPSVWPGKKT-IQLTHEQQLILNHKMEPLQVVKIMAFAGTGKTSTLVKYAEKWSQSRFLYVTFNKSIAKQAERVFPSNVICKTFHSMAYGHIGRKYQSKKKLNLFKLTPFMVNSVLAEGKGGFIRAKLVCKTLENFFASADEELTIDHVPIWCKNSQGQRVMVEQSEKLNGVLEASRLWDNMRKLGECTEEAHQMTHDGYLKLWQLSKPSLASFDAIFVDEAQDCTPAIMNIVLSQPCGKIFVGDPHQQIYTFRGAVNALFTVPHTHVFYLTQSFRFGVEIAYVGATILDVCKRVRKKTLVGGNHQSGIRGD--------------AKGQVALLSRTNANVFDEAVRVTEGEFPSRIHLIGGIKSFGLDRIIDIWILLQPEEERRKQNLVIKDKFIRRWVHKEG--FSGFKRYVTAAEDKELEAKIAVVEKYNIRIPELVQRIEKCHIEDLDFAEYILGTVHKAKGLEFDTVHVLDDFVKVPCARHNLPQLPHFRVESFSEDEWNLLYVAVTRAKKRLIMTKSLENILTLAGEYFLQAELTSNVLKTG-VVRCCVGQCNNAIPVDTVLTMKKLPITYSNRKENKGGYLCHSCAEQRIGPLAFLTASPEQVRAMERTVENIVLPRHEALLFLVF-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AC58J8C6-1", "uniprot_id": "A0AC58J8C6_DANRE", "id": "A0AC58J8C6-1", "name": "F-box DNA helicase 1", "aln": "MPVLFHSVYLHMFPIGRAKRRHLGPSECNDLAQSNTGSQSLTQPFSVSLNNRDPNQRLQPRTPTKRRRRASDG---------AGQQKGITDFFSVTGVISSSPQKGTKTPIKNEEE----------------------EEEKCIPQEENVE----EDFMEGITEDMFDDDFEMEIVSVK--KEQAEVAVNK---------GDEEDS-VEALPDAHFGLLGVRGGQEVPQGHVQDLPEEILREVFALLPAQDLFQHISLVCRHWRDVVMDPKFLPWKKLYCRYRKRETEGVKEVRSILDANQISKKEDLCLLNMLRYMSGFKHSKRVNVEDVLTCIKRHRLYTHAEACMKDRLPDMVDEEG-PNPWSAMALLLILADGVKDILDLVALLRRSGCLLTTGGISEYLWAVATLLLAMRERNINISNRWHYNIFYVLHLMENASPTSLKDNRQ-----------LITHEQQQILNHDIQHHHVVKIMAFAGTGKTTTLVKYAQQRPDLRFLYLAFNKSVAVQANRLFPHNVECSTVHSMAYRSVGVRYKNIRKLSS-NLKPFDVAWVLPKGHGGFVNAKVVTQTLNNYWASTDQRVDTQHVPFEYKNTKGLREQPDEEAKRTFVSLAQNIWDQMVEMRTRRDRVYNMTHDGYLKLWQLENPVLDRYDAIFIDEAQDCTPVIMDIMLSQRCGKILVGDPHQQIYTFRGAVNALYFVQHTHIYYLTQSFRFGSEIAYVGASILDGCKGV-KQILVGGHQDGSVRGEDTQTLLHLKHGQKMPEGSVAILSRCNVTVFSEAVRLTEVNPNCKICIVGGVENFGLDKIMDIWVLTQSEDTRKKDNLKIKDFFIRNFCKEKMGGFMGLKGYAIASEDRELEGKLAMVEKYNKRIPELVRRIYDCAQGSPQDADFILGTVHKSKGLEFDVVVVTDDFAKVPCARHNLRRAGGFSIDNVPDDEWNLIYVAITRAKKTLYISKTITNLITFTGEYFLRSEQTSSLLSKDPALTCSTKDCENQISADSVLSMCKLPVRYMDS-VDAGGVQCLTCVEQRVGPTAFLLSPPERVRSMPYTNERIDLPINVAMLLALLF", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : * **:** :*:.**:* : ****. .*****: * *:. ** *. . *.:* .*: . ..* ..* *.. * *. .:: ** : . :*:::. . : : :: ** . .: * * :.:**:::**** **. . *: **.*:**.:**:**.:**: ::****: **::: ** *:****** ** .* :.*.:* .**. *.*..***:**::** : * * *: * ** .:: * * .****::::***: * * *: :* :::*:. *:** *: ***. . :* .::* *:.:*.** ****:.****** ****** *:* **:.. : * ..: :***** ****.:: :*************:******:: .: ****::****:* **: :** ** *.*.***** :* :*: :**. :*.** * **.:*:***:.**:* :**:*::**:*:.: :***: **::* * ::. * . * *..:**:* :: :..::************.:* * :****:********.**:*:*** ****:******************: * ***::********* *******:*** ** * *: ****:::..:**: :*.**:*** *..**.****:** : .:* ::**::.****:*:*** * *.*: *:* :* *** ***.: ::: * *:* *. *:**:***.*:*:***** ******.** * . : *::*******:******.* * ***.********* : * ::...:*****:***:***** * ::*:: *::*::*****::* **.:*... .: *.. :*:* *..*::*:* ***: * : : ** * :*.***:** *** :.**:**:* * * : ** : *:*: :: ", "identical_positions": 469, "similar_positions": 290, "identity": "43.35%" }, { "cls_id": "homologset.agr.MGI:1354701", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9JHJ8-1", "uniprot_id": "ICOSL_MOUSE", "id": "Q9JHJ8-1", "name": "ICOS ligand", "aln": "MQLKCPCFVSLGTRQPVWKKLHVSSGFFSGLGLFLLLLSSLCAASAETEVGAMVGSNVVLSCIDPHRRHFNLSGLYVYWQIE-NPEVSVTYYLP--YKSPGINVDSSYKNRGHLSLDSMKQGNFSLYLKNVTPQDTQEFTCRVFMNTATELVKILEEVVRLRVAANFSTPVISTSDSSNPGQERTYTCMSKNGYPEPNLYWINTTDNSLIDTALQNNTVYLNKLGLYDVISTLRLPWTSRGDVLCCVENVALHQNITSISQAESFTG---NNTKNPQETHNNELKVLVPVLAVLAAAAFVSFIIYR---RTRPHRSYTGPKTV--QLELTDHA", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "F1LVL2-1", "uniprot_id": "F1LVL2_RAT", "id": "F1LVL2-1", "name": "ICOS ligand", "aln": "MQLK----------------------FFSGPGLFLLLFCSLCVEAEVKEVNAMVGSDVELRCVYPRRSHFSLDDLYVYWQIVDEAKTVVTYYLPSANESSTIHVSNSYKNRAHLSPDLMKEGDFSLHLQNVTPQDTQEFKCLVFR-MSTVLGKALEEVVRLRVAANFSTPVISTSGSSDPGQERTFTCMSKNGYPEPNLYWINRTDNTLIDETLQNNTVYLNELGLYDVVSTLRIPWTPHVDVICCVENVALHQNITSISRADSFTGS--MNTERPQEIHREATKVLFYVLAALLAVVVVIFIIVLYRCRRRPCQSYTGPRAV--QLELTDHS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O75144-1", "uniprot_id": "ICOSL_HUMAN", "id": "O75144-1", "name": "ICOS ligand", "aln": "MRLG-------------------------SPGLLFLLFSSLRADTQEKEVRAMVGSDVELSCACPEGSRFDLNDVYVYWQTS-ESKTVVTYHIP--QNSSLENVDSRYRNRALMSPAGMLRGDFSLRLFNVTPQDEQKFHCLVLS-QSLGFQEVLSVEVTLHVAANFSVPVVSAPHSPSQ-DELTFTCTSINGYPRPNVYWINKTDNSLLDQALQNDTVFLNMRGLYDVVSVLRIARTPSVNIGCCIENVLLQQNLTVGSQTGNDIGERDKITENPVSTG-EKNAATWSILAVLCLLVVVAVAIGWVCRDRCLQHSYAGAWAVSPETELTGHV", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*:* . **::**:.** . : .** *****:* * * *. :*.*..:***** :.:. ***::* :*. :*.. *:**. :* * .*:*** * ****** *:* * *: : : : *. * *:******.**:*:. *.. :* *:** * ****.**:**** ***:*:* :***:**:** *****:*.**:. *. :: **:*** *:**:* *:: . * *:.* . : . :**.* ..* . * :**:*. :* : ***.* ", "identical_positions": 127, "similar_positions": 83, "identity": "38.14%" }, { "cls_id": "homologset.agr.MGI:1354702", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0ABK0LNB3-1", "uniprot_id": "A0ABK0LNB3_RAT", "id": "A0ABK0LNB3-1", "name": "", "aln": "MRMKRGGRDSDQDSPEEGTAEKPKKPRTTHECSQPCDWGNLLQDIVLHVFKYLPLLDRAHASQVCRNWNQVFHMPDLWRCFEFELNQPATSYLKATHPELIKQIIKRHSNHLQYVSFKVDSSKESAEAACDILSQLVNCSLKTLGLISTARPSFMDLPKSHFISALTVVFVNSKSLSSLKIDDTPVDDPSLKVLVANNSDTLKLLKMSSCPHVSPAGILCVADQCHGLRELALNYHLLSDELLLALSSEKHVRLEHLRIDVVSENPGQTHFHTIQKSSWDAFIKHSPKVNLVMYFFLYEEEFDPFFRYEIPATHLYFGRSVSKDVLGRVGMTCPRLVELVVCANGLRPLDEELIRIAERCKNLSAIGLGECEVSCSAFVEFVKMCGGRLSQLSIMEEVLIPDQKYSLEQIHWEVSKHLGRVWFPDMMPTW", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8C4V4-1", "uniprot_id": "FBXL3_MOUSE", "id": "Q8C4V4-1", "name": "F-box/LRR-repeat protein 3", "aln": "--MKRGGRDSDQDSAEEGTAEKPKRPRTTQERSQPCDWGNLLQDIVLHVFKYLPLLDRAHASQVCRNWNQVFHMPDLWRCFEFELNQPATSYLKATHPELIKQIIKRHSNHLQYVSFKVDSSKESAEAACDILSQLVNCSLKTLGLISTARPSFMDLPKSHFISALTVVFVNSKSLSSLKIDDTPVDDPSLKVLVANNSDTLKLLKMSSCPHVSPAGILCVADQCHGLRELALNYHLLSDELLLALSSEKHVRLEHLRIDVVSENPGQTHFHTIQKSSWDAFIKHSPKVNLVMYFFLYEEEFDPFFRYEIPATHLYFGRSVSKDVLGRVGMTCPRLVELVVCANGLRPLDEELIRIAERCKNLSAIGLGECEVSCSAFVEFVKMCGGRLSQLSIMEEVLIPDQKYSLEQIHWEVSKHLGRVWFPDMMPTW", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9UKT7-1", "uniprot_id": "FBXL3_HUMAN", "id": "Q9UKT7-1", "name": "F-box/LRR-repeat protein 3", "aln": "--MKRGGRDSDRNSSEEGTAEKSKKLRTTNEHSQTCDWGNLLQDIILQVFKYLPLLDRAHASQVCRNWNQVFHMPDLWRCFEFELNQPATSYLKATHPELIKQIIKRHSNHLQYVSFKVDSSKESAEAACDILSQLVNCSLKTLGLISTARPSFMDLPKSHFISALTVVFVNSKSLSSLKIDDTPVDDPSLKVLVANNSDTLKLLKMSSCPHVSPAGILCVADQCHGLRELALNYHLLSDELLLALSSEKHVRLEHLRIDVVSENPGQTHFHTIQKSSWDAFIRHSPKVNLVMYFFLYEEEFDPFFRYEIPATHLYFGRSVSKDVLGRVGMTCPRLVELVVCANGLRPLDEELIRIAERCKNLSAIGLGECEVSCSAFVEFVKMCGGRLSQLSIMEEVLIPDQKYSLEQIHWEVSKHLGRVWFPDMMPTW", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *********::*.*******.*: ***:* **.**********:*:*******************************************************************************************************************************************************************************************************************************************:**************************************************************************************************************************************************", "identical_positions": 416, "similar_positions": 10, "identity": "96.74%" }, { "cls_id": "homologset.agr.MGI:1354704", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0ABK0KYW3-1", "uniprot_id": "A0ABK0KYW3_RAT", "id": "A0ABK0KYW3-1", "name": "F-box/LRR-repeat protein 17", "aln": "MGHLLSKEPRNRPSQKGPRCCSWCRRRRPLLRLPHRTPAKASPQPAAPRSRDCFFRGPCMLCFIVHSPGAPAPAGLEEEPPLSPPP---RDGAYATVSS-QHLARRYAALAAEDCAAAARRFLLS---SAAAAAASSS-PASCCKELGLAAAAAWEQQGRSLFLAGVGPVRFLGPPAAVQLFRGSPAPP-QAEPTTVLEMVCKRKGAGVPACTPCKQPRCGGGGCGGGGGGGGG--PAGGGASPPRPPDAGCCQAPEQPPPPLCPAPASPASECAPIEAAAGDAVRAGGTAPSSAQQQPESGDSDCQEPPENPCDCHREPPPEIPDINQLPPSILLKIFSNLSLDERCLSASLVCKYWRDLCLDFQFWKQLDLSSRQQVTDELLEKIASRSQNIVEINISDCRSMSDSGVCVLAFKCPGLLRYTAYRCKQLSDTSIIAVASHCPLLQKVHVGNQDKLTDEGLKQLGSKCRELKDIHFGQCYKISDEGMVVIAKSCLKLQRIYMQENKLVTDQSVKAFAEHCPDLQCVGFMGCSVTSKGVIHLTKLRNLSSLDLRHITELDNETVMEIVKRCKNLSSLNLCLNWIINDRCVEVIAKEGQSLKELYLVSCKITDYALIAIGRYSVTIETVDVGWCKEITDQGATLIAQSSKSLRYLGLMRCDKVNEVTVEQLVQQYPHITFSTVLQDCKRTLERAYQMGWTPNMSAATS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9QZN1-1", "uniprot_id": "FXL17_MOUSE", "id": "Q9QZN1-1", "name": "F-box/LRR-repeat protein 17", "aln": "MGHLLSKEPRNRPSQKRPRCCSWCRRRRPLLRLPRRALAKASPQPAAPRSRDCFFRGPCMLCFIVHSPGAPASAGLEEEPPLSPPPPPPRDGAYAAVSS-QHLARRYAALAAEDCAAAARRFLLS---SAAAAAAAASSPASCCKELGLAAAAAWEQQGRSLFLAGVGPVRFLGPLAAVQLFRAPPAPPPQAEPATALEMVCKRKGAGVPACTPCKQPRCGCGGCGGGGGGGGG--PAGGGASPPRPPDAGCCQAPEQPPPPLCPAPASPASECAPIVAAAGDTVRAGGTAPSSAQQQPESGDADCQEPPENPCDCHREPPPEIPDINQLPPSILLKIFSNLSLNERCLSASLVCKYWRDLCLDFQFWKQLDLSSRQQVTDELLEKIASRSQNIIEINISDCRSLSDSGVCVLAFKCPGLLRYTAYRCKQLSDTSIIAVASHCPLLQKVHVGNQDKLTDEGLKQLGSRCRELKDIHFGQCYKISDEGMIVIAKSCLKLQRIYMQENKLVTDQSVKAFAEHCPELQYVGFMGCSVTSKGVIHLTKLRNLSSLDLRHITELDNETVMEIVKRCKNLSSLNLCLNWIINDRCVEVIAKEGQNLKELYLVSCKITDYALIAIGRYSVTIETVDVGWCKEITDQGATLIAQSSKSLRYLGLMRCDKVNELTVEQLVQQYPHITFSTVLQDCKRTLERAYQMGWTPNMSAATS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9UF56-1", "uniprot_id": "FXL17_HUMAN", "id": "Q9UF56-1", "name": "F-box/LRR-repeat protein 17", "aln": "MGHLLSKEPRNRPSQKRPRCCSWCRRRRPLLRLPRRTPAKVPPQPAAPRSRDCFFRGPCMLCFIVHSPGAPAPAGPEEEPPLSPPP---RDGAYAAASSSQHLARRYAALAAEDCAAAARRFLLSSAAAAAAAAASASSPASCCKELGLAAAAAWEQQGRSLFLASLGPVRFLGPPAAVQLFRGPTPSP--AELPTPPEMVCKRKGAGVPACTPCKQPRCGGGGCGGGGGGGGGGGPAGGGASPPRPPDAGCCQAPEQPPQPLCPPPSSPTSEGAPTEAG-GDAVRAGGTAPLSAQQQHECGDADCRESPENPCDCHREPPPETPDINQLPPSILLKIFSNLSLDERCLSASLVCKYWRDLCLDFQFWKQLDLSSRQQVTDELLEKIASRSQNIIEINISDCRSMSDNGVCVLAFKCPGLLRYTAYRCKQLSDTSIIAVASHCPLLQKVHVGNQDKLTDEGLKQLGSKCRELKDIHFGQCYKISDEGMIVIAKGCLKLQRIYMQENKLVTDQSVKAFAEHCPELQYVGFMGCSVTSKGVIHLTKLRNLSSLDLRHITELDNETVMEIVKRCKNLSSLNLCLNWIINDRCVEVIAKEGQNLKELYLVSCKITDYALIAIGRYSMTIETVDVGWCKEITDQGATLIAQSSKSLRYLGLMRCDKVNEVTVEQLVQQYPHITFSTVLQDCKRTLERAYQMGWTPNMSAASS", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "**************** *****************:*: **..******************************.** ********** ******:.** ************************* :******::* **************************.:******** *******.....* ** .* *********************** ************ ************************ ****.*:**:** ** *. **:******** ***** *.**:**:*.************** ********************:*************************************************:*********:**.***********************************************************:********************:****.****************************:** ************************************************************************.***********************:*****************************************:****************************************:*", "identical_positions": 639, "similar_positions": 39, "identity": "90.38%" }, { "cls_id": "homologset.agr.MGI:1354705", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9QXW0-1", "uniprot_id": "FBXL6_MOUSE", "id": "Q9QXW0-1", "name": "F-box/LRR-repeat protein 6", "aln": "-------------MAPVASRRVRRRVRSSKRPDARGRSAEDWWWDRLAPR---------GSGYHLLQADSMLLVLPDLEPP----RARAHRRARRRAPRSLARGPTAVAKPRT------------KPRPEPSLDQGLDS---GWGDRIPLEVLVHIFGLLVAAHGPMPFLGRAARVCRHWHEATSHPSLWHTVTLSPSLVGRAGKGNLKG-EKKLLACLEWLVPNRFSQLQSLTLIHWKSQVHSVLELVSKFCPRLTFLKLSDCHTVTAETLVMLARACCQLHSLDLHHSMVESTAVVSFLEEAGSRMRKLWLTYSSQTTAILGALLDNCCPQLQVLQVSTGMNCNNTPLQLPVEALQKGCPQLQVLRLLNLIWLPKPCGRGVPQGPGFPSLEELCLAGSTCNFVSNEVLGRLLHRSPKLRMLDLRGCARVTPSGLCHLPCQELEQLYLGLYGISDGLTLAKDGSPLLTRKWYHTLRELDFSGQGFSEKDLEQALAVFSGTPGGLHPALCSLNLRGTRVTPSTVSSVISGCPGLLYLNLESCRCLPRGLKRVYRGLEEVQWCLEQLLTSPPSAKEPT", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8N531-1", "uniprot_id": "FBXL6_HUMAN", "id": "Q8N531-1", "name": "F-box/LRR-repeat protein 6", "aln": "-------------MAAPASRQVRRRARAAPRP----RSAEDWWWDRLAPR---------GSGYHLLQSDSMLLVLSEPGPA----RPRAQRRASRRTPRQPPRGPSAAAKPKAGLRSEAAAAPAPAPAPTPTPEEGPDA---GWGDRIPLEILVQIFGLLVAADGPMPFLGRAARVCRRWQEAASQPALWHTVTLSSPLVGRPAKGGVKA-EKKLLASLEWLMPNRFSQLQRLTLIHWKSQVHPVLKLVGECCPRLTFLKLSGCHGVTADALVMLAKACCQLHSLDLQHSMVESTAVVSFLEEAGSRMRKLWLTYSSQTTAILGALLGSCCPQLQVLEVSTGINRNSIPLQLPVEALQKGCPQLQVLRLLNLMWLPKPPGRGVAPGPGFPSLEELCLASSTCNFVSNEVLGRLLHGSPNLRLLDLRGCARITPAGLQDLPCRELEQLHLGLYGTSDRLTLAKEGSPFLTQKWCHTLRELDLSGQGFSEKDLEQALAAFLSTPGGSHPALCSLNLRGTRVTPSTVSSVISGCPGLLYLNLESCRCLPRGLKRAYRGLEEVQWCLEQLLTSPSPS----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F1R393-1", "uniprot_id": "F1R393_DANRE", "id": "F1R393-1", "name": "", "aln": "MESTVAQASSAEMSAAQSSRAETSPTKPAKRKAPLKRKADSLKDDKSKKKKRKPVKRTVRPNYTVQEGEDMLLIISNISSGDSVWKPKRKVGKKKKTNKKAKTKGSTSKKEKAPVKTEVLKVREETDDKHDVMDSAKTDRFDHWGQSLPLEILVKIFQFAVFQDGAVPLLCRVGRVCRLWNGAASSPILWRSVSIGYCWIE-PGKSQLPGTEQKIKNTVDWLAENRLFQLREFSLCHWKKNVDYVIQKVSQSCLSLHSLKLSYCTGMTEKAFQNLGADCQSLEDINVQHSEINVDGLVSFLEAYGNQIKKIYFTHSTKSDKLLSALSKGCCPELRLLEINTKLDGGYSQLPICIQGLQIGCPKLQTFRLMNVTAVPKMIRNIPSSTCGFPMLEELCIATSFHSFMTDNDLNNVLHGSPNLRVLDLRGGSRITPTGLYALPCERLECFYWGLYFNSNTMVASKKGIHMLAQKWSNTLRELDLANQPFSEEDLEIAMGHLAHSVG--VEFFRSLNLSGTKITSSALRLLINQAPALKYLNLSSCRYLPRGLKRLYHGQEDIQLLLDKLD----------", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *. :** .:.: * *.*:. *: : ..* : :.:.***::.: . :.: : ::: :. :: * :: :.. **: :***:**:** : * .*.:*:* *..**** *: *:* * **::*::. : ..*. : . *:*: ::** **: **: ::* ***.:*. *:: *.: * * **** * :* .:: *. * .*..::::** :: .:***** *.:::*:::*:*::: :*.** .***:*::*::.* :: . * : ::.** ***:**.:**:*: :** . . *** *****:* * .*:::: *..:** **:**:***** :*:**:** ***..** :: *** *: :. :*.* :*::** :******::.* ***:*** *:. : : * : **** **::*.*:: :*. .*.* ****.*** ******* *:* *::* *::* ", "identical_positions": 185, "similar_positions": 180, "identity": "32.06%" }, { "cls_id": "homologset.agr.MGI:1354706", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I6A636-1", "uniprot_id": "A0A8I6A636_RAT", "id": "A0A8I6A636-1", "name": "", "aln": "MMAFAPPKSIDGPKMQTKMSTWTPLNHQLLNDQVFEERRALLGKWFDKWTDSQRRRILTGLLERCSLSQQKFCCRKLQEKIPAEALDFTTKLPRVLSVYIFSFLDPRSLCRCAQVSWYWKSLAELDQLWMLKCLRFNWYISFSPTPFEQGVWKKHYIQMVRELHVTKPKTPPKDGFITADVQPIPGSSPEEKQSPSLAFRSSSSLRKKNNPGE------KELPPWRSSDKHPTDIIRFNYLDNCDP-ELFRLGRRK-RKEVTPDFKQQFRDKKNKLQDRARLRKAQSLMSRRD----------LLSL---------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9QZM9-1", "uniprot_id": "FBX16_MOUSE", "id": "Q9QZM9-1", "name": "F-box only protein 16", "aln": "MMAFAPPKSIDGPKMQTKMSTWTPLNHQLLNDQVFEERRALLGKWFDKWTDSQRRRILTGLLERCSLSQQKFCCRKLQEKIPAEALDFTTKLPRVLSVYIFSFLDPRSLCRCAQVSWYWKSLAELDQLWMLKCLRFNWYISFSPTPFEQGVWKKHYIQMVRELHVTKPKTPPKDEFTTADVQPIPGNSPDEKQSPSLAFRSSSSLRKKNNPGE------KELPPWRSSDKHPTDIIRFNYLDNCDP-ELFRLGRRK-RSEVTPDFKRQLRDKKNKLQDRARLRKAQSLISLSSPPKVPVRLAWPLHLPVAPSDREAATEALLEHLQKHPG-LQSPSPRLQSQS---------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8IX29-1", "uniprot_id": "FBX16_HUMAN", "id": "Q8IX29-1", "name": "F-box only protein 16", "aln": "MMAFAPPKNTDGPKMQTKMSTWTPLNHQLLNDRVFEERRALLGKWFDKWTDSQRRRILTGLLERCSLSQQKFCCRKLQEKIPAEALDFTTKLPRVLSLYIFSFLDPRSLCRCAQVCWHWKNLAELDQLWMLKCLRFNWYINFSPTPFEQGIWKKHYIQMVKELHITKPKTPPKDGFVIADVQLVTSNSPEEKQSPLSAFRSSSSLRKKNNSGE------KALPPWRSSDKHPTDIIRFNYLDNRDPMETVQQGRRK-RNQMTPDFSRQSHDKKNKLQDRTRLRKAQSMMSRRN----------PFPLCP-------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1N563-1", "uniprot_id": "A0A8M1N563_DANRE", "id": "A0A8M1N563-1", "name": "", "aln": "-MPKAP-----STKMQTKLSTWTPLNHQLSNAHVFEERRNLLGKWFEKWTDSQRKQVLQDFFSRCSAGQLKHLRQTLSSWVPEETLDFTTVLPRVISLYIFSYLDPRSLCRCAQVSWHWKNLVELDQLWMPKCLKLGWCITFTPTPFEQGVWKRQYIETVQELHISRPKVPVKEEFIVPDVKVIG--SETEGSLPLTGHRDLLGLHGRSKNGNDLGKSAKGLPPWRDSDRHPTDTIRFNYLDNLHPGEHARKALLKTRQEDTIKAPSHSTYKLRKAKSLMFLSLDLSKAGKPSHNRPKWAARNLEALPADKDSIKRISQTSQWNAGIRPGPVRPPVPRLSKEGFRASQRSHRSTPTVTLFEGQP", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *. ** ..*****:********** * :****** ******:*******:::* .::.*** .* *. :.*.. :* *:***** ****:*:****:************.*:**.*.******* ***::.* *.*:*******:**::**: *:***:::**.* *: * .**: : * * . * ..*. .*: :.: *: * *****.**:**** ******** .* * : . * *.: * . : * .* :. * * . . * ", "identical_positions": 148, "similar_positions": 70, "identity": "40.66%" }, { "cls_id": "homologset.agr.MGI:1354707", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9QZM8-1", "uniprot_id": "FBX17_MOUSE", "id": "Q9QZM8-1", "name": "F-box only protein 17", "aln": "MGARPSRRQMTEARRLALTKLPPELLVQVLSHVPPRALVTRCRPVCRAWRDLVDGPSIWLLQLARDRSAEGRALYALAQRCPADADADADADGNRHDEFPFCALARFCLRAPFGRNLIHNSCGEQGFRGWEVEHGGNGWAVEKNLTLVPGAPSQTCFVTSFEWCSKRQLVDLVKEGVWQELLDSGQIEICIADWWGARENCGCIYRLRVRLLDEYENEVVKFSASPNPVLQWTERSCRQVSHVFTNFGKGIRYVSFEQYGRDTRSWVGHYGALVTHSSVRVRIRLS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q96EF6-1", "uniprot_id": "FBX17_HUMAN", "id": "Q96EF6-1", "name": "F-box only protein 17", "aln": "MGARLSRRRLPADPSLALDALPPELLVQVLSHVPPRSLVTRCRPVCRAWRDIVDGPTVWLLQLARDRSAEGRALYAVAQRCLP-----SNED---KEEFPLCALARYCLRAPFGRNLIFNSCGEQGFRGWEVEHGGNGWAIEKNLTPVPGAPSQTCFVTSFEWCSKRQLVDLVMEGVWQELLDSAQIEICVADWWGARENCGCVYQLRVRLLDVYEKEVVKFSASPDPVLQWTERGCRQVSHVFTNFGKGIRYVSFEQYGRDVSSWVGHYGALVTHSSVRVRIRLS", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6AY27-1", "uniprot_id": "FBX17_RAT", "id": "Q6AY27-1", "name": "F-box only protein 17", "aln": "MGAQPSRRRMTEAQHMALAELPPELLLQVLSHVPPRALVTRCRPVCRAWRDLVDGPSVWLLQLARDRSAEGRALYALAQSCPA------DRNG--HDDFPLCALARFCLLAPLGRNLIYNSCGEQGFRGWEVEHGGNGWAVEKNLTMVPGAPSQTCFVTSFEWCFKRQLVDLVKEGVWQELLDSAQIEIYIADWWGARENCGCIYRLRVRLLDEHENEVVKFSASPNPVLQWTERSCRQVS-------------------PDCSLNPGLLQGLS---------RLH", "tax_id": 10116, "tax_name": "Rat" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "***: ***::. :** ******:*********:**************:****::******************:** * . : : :::**:*****:** **:*****.*********************:***** ***************** ******** **********.**** :************:*:******* :*:*********:********.***** * * .* ** ", "identical_positions": 191, "similar_positions": 31, "identity": "66.78%" }, { "cls_id": "homologset.agr.MGI:1354708", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "B2RYN2-1", "uniprot_id": "FBX31_RAT", "id": "B2RYN2-1", "name": "F-box only protein 31", "aln": "----MAVCARLCGVGPARGCRRRQQRRGPAETAAADSEADTDPEEERIEAG-------------------------------------PARCSLLELPPELLVEIFASLPGTDLPSLAQVCSRFRRILHTDTIWRRRCREEYGVCENLRKLEITGVSCR-----------------------------DVYAKLLHRYRHILGLWQPDIGPYGGLLNVVVDGLFIIGWMYLPPHDPHVGDPMRFKPLFRIHLMERKSATVECMYGHKGPHNGHIQIVKRDEFSTKCNQTDHHRMSGGRQEEFRTWLREEWGRTLEDIFHEHMQELILMKFIYTSQYDNCLTYRRIYLPPSHPDDLIKPGLFKGTYGSHGLEIVMLSFHGSRARGTKITGDPNIPAGQQTVEIDLQRRIQLPDVENLRNFNELSRIVLEVREQVRQEQ-----EAGEG-------------PAPHREPAVKDPEGPPAKASKEAGPGAEAAEQSSTSGQGQPFVLPAGVSSRNEDYPRTCRLCFYGTGLIAGHGFTSPERTPGVFVLFDEDRFGFLWLELKSFSLYSRVQATFQNADAPSPQAFDEMLRNIQSLTS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q3TQF0-1", "uniprot_id": "FBX31_MOUSE", "id": "Q3TQF0-1", "name": "F-box only protein 31", "aln": "----MAVCARLCGVGPARGCRRRQQRRGPAETAAADSEADTDPEEERIEAG-------------------------------------PARCSLLELPPELLVEIFASLPGTDLPSLAQVCSRFRRILHTDTIWRRRCREEYGVCENLRKLEITGVSCR-----------------------------DVYAKLLHRYRHILGLWQPDIGPYGGLLNVVVDGLFIIGWMYLPPHDPHVGDPMRFKPLFRIHLMERKSATVECMYGHKGPHNGHIQIVKRDEFSTKCNQTDHHRMSGGRQEEFRTWLREEWGRTLEDIFHEHMQELILMKFIYTSQYDNCLTYRRIYLPPSHPDDLIKPGLFKGTYGSHGLEIVMLSFHGSRARGTKITGDPNIPAGQQTVEIDLQRRIQLPDVENLRNFNELSRIVLEVREQVRQEQ-----EAGEG-------------AAPPREPSAKAADGPPAKDGKEPGGGAEAAEQSASSGQGQPFVLPVGVSSRNEDYPRTCRLCFYGTGLIAGHGFTSPERTPGVFVLFDEDRFGFLWLELKSFSLYSRVQATFQNAAAPSPQAFDEMLRNIQSLTS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q5XUX0-1", "uniprot_id": "FBX31_HUMAN", "id": "Q5XUX0-1", "name": "F-box only protein 31", "aln": "----MAVCARLCGVGPSRGCRRRQQRRGPAETAAADSEPDTDPEEERIEASA-----------------------GVGGGLCAGPSPPPPRCSLLELPPELLVEIFASLPGTDLPSLAQVCTKFRRILHTDTIWRRRCREEYGVCENLRKLEITGVSCR-----------------------------DVYAKLLHRYRHILGLWQPDIGPYGGLLNVVVDGLFIIGWMYLPPHDPHVDDPMRFKPLFRIHLMERKAATVECMYGHKGPHHGHIQIVKKDEFSTKCNQTDHHRMSGGRQEEFRTWLREEWGRTLEDIFHEHMQELILMKFIYTSQYDNCLTYRRIYLPPSRPDDLIKPGLFKGTYGSHGLEIVMLSFHGRRARGTKITGDPNIPAGQQTVEIDLRHRIQLPDLENQRNFNELSRIVLEVRERVRQEQQEGGHEAGEGRGRQGPRESQPSPAQPRAEAPSKGPDGTPGEDGGEPGDAVAAAEQPAQCGQGQPFVLPVGVSSRNEDYPRTCRMCFYGTGLIAGHGFTSPERTPGVFILFDEDRFGFVWLELKSFSLYSRVQATFRNADAPSPQAFDEMLKNIQSLTS", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AC58IYD6-1", "uniprot_id": "A0AC58IYD6_DANRE", "id": "A0AC58IYD6-1", "name": "", "aln": "MLLRMAVCARLCGVGQSRRCRRRQRHSQADQDSDSDMEMEEGEEEERVVGKAKDEPDGSGIGGGCHSSCGAGPSGAGSGASASGSAGPPHPQSLLDLPPELLVEIFASLPGIALPNLALVCKKFRQILNTETIWRRRCTEEFGMRDDLRKMEIVGISSRDLYVKRVNPQVKSGRFMKLLPDYEHMDYRDVYTHLLHPYRHILGLWQPDIGPYGGLLNVVVDGLFIIGWMYLPPHDPRVEDPMRRRPLFRIHMWEKNKATVECMYGHKGPHKGDIQTVKKDEFSTKCNQTDHHRMPGGRQEEFRTWLEEEWGRTLEDIFHEHMQELILMKFIYTSQYDNCLTYRRIYLPPCLPSDLLQPGLFKGTYGSHGLEIIMLSFHGSKAKATKLTGDPNVPAGQLTLEIDLQRPVRLPDLEQQRSMEELSRLVLGVHEEVQRAS------QSQG------------VQAEAAESEVEASDSAPPAGAEDEEPAAAAAPKT------QAFVLPLGVMARNEVYPRTCKMCFYGTGLIAGHGFTSPERTPGLFILFDDDRFGFIWLELKSFSLYSRLTDQLTHAQAPSMQRFENMLRNMQSWTS", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *********** :* *****:: . : : :* * : . ****: . * ***:*************** **.** **.:**:**:*:******* **:*: ::***:**.*:*.* ***::*** ***************************************:* **** :******: *:: *************:*.** **:***************.***********.******************************************. *.**::***************:****** :*:.**:*****:**** *:****:: ::***:*: *.::****:** *:*.*:: . .:* *. : .:..* . : .. ** :. *.**** ** :*** *****::*********************:*:***:*****:************: : :* *** * *::**:*:** **", "identical_positions": 344, "similar_positions": 93, "identity": "57.82%" }, { "cls_id": "homologset.agr.MGI:1354709", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZJK3-1", "uniprot_id": "D3ZJK3_RAT", "id": "D3ZJK3-1", "name": "Histone deacetylase complex subunit SAP30L", "aln": "MN-GFSTEEDSREGPPAAP-AAAPGYGQSCCLIADGERCVRPAGNASFSKRVQKSISQKKLKLDIDKSVRHLYICDFHKNFIQSVRNKRKRKTSDDGGDSPEHDADIPEV-DLFQLQVNTLRRYKRHYKLQTRPGFNKAQLAETVSRHFRNIPVNEKETLAYFIYMVKSNRSRLDQKPEGSKQLE", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q5SQF8-1", "uniprot_id": "SP30L_MOUSE", "id": "Q5SQF8-1", "name": "Histone deacetylase complex subunit SAP30L", "aln": "MN-GFSTEEDSREGPPAAP-AAAPGYGQSCCLIADGERCVRPAGNASFSKRVQKSISQKKLKLDIDKSVRHLYICDFHKNFIQSVRNKRKRKASDDGGDSPEHDADIPEV-DLFQLQVNTLRRYKRHYKLQTRPGFNKAQLAETVSRHFRNIPVNEKETLAYFIYMVKSNRSRLDQKSEGSKQLE", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9HAJ7-1", "uniprot_id": "SP30L_HUMAN", "id": "Q9HAJ7-1", "name": "Histone deacetylase complex subunit SAP30L", "aln": "MN-GFSTEEDSREGPPAAPAAAAPGYGQSCCLIEDGERCVRPAGNASFSKRVQKSISQKKLKLDIDKSVRHLYICDFHKNFIQSVRNKRKRKTSDDGGDSPEHDTDIPEV-DLFQLQVNTLRRYKRHYKLQTRPGFNKAQLAETVSRHFRNIPVNEKETLAYFIYMVKSNKSRLDQKSEGGKQLE", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6NYV5-1", "uniprot_id": "SP30L_DANRE", "id": "Q6NYV5-1", "name": "Histone deacetylase complex subunit SAP30L", "aln": "MN-GFSTEEDSHDGPPAPP-----FFGQSCCLIEDAERCGRPAGNASFSKRIQKSISQRKLKLDIDKSVRHLYICDFHKNFIQSVRNKRKRKTSDDGGESPDHEVEVPEV-DLFQLQVNTLRRYKRHYKIQTRPGLNKAQLAETVSRHFRNIPVNEKETLTYFIYMVKSSKSRLDQKSDSSKQVE", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VXB3-1", "uniprot_id": "SAP30_DROME", "id": "Q9VXB3-1", "name": "Histone deacetylase complex subunit SAP30 homolog", "aln": "MNNGFSTGEEDSRG----------HTDQTCCLIDDMERCRNQAGYASYSKRIQKTVAQKRLKLSSDPAAQHIYICDHHKERIQSVRTKRRRKDSED--DSNETDTDLHEFPDLYQLGVSTLRRYKRHFKVQTRQGMKRAQLADTIMKHFKTIPIKEKEIITFFVYMVKMGSNKLDQKNGLGNDTT", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "** **** *:. * .*:**** * *** . ** **:***:**:::*::***. * :.:*:****.**: *****.**:** *:* :* : :.:: *. **:** *.********:*:*** *:::****:*: :**:.**::*** :::*:**** . .:**** .:: ", "identical_positions": 90, "similar_positions": 53, "identity": "48.65%" }, { "cls_id": "homologset.agr.MGI:1354710", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P98200-1", "uniprot_id": "AT8A2_MOUSE", "id": "P98200-1", "name": "Phospholipid-transporting ATPase IB", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------MSRATSVG---------------------------------------------------------------DQLEAPARIIYLNQSHLN---KFCDNRISTAKYSVLTFLPRFLYEQIRRAANAFFLFIALLQQIPDVSPTGRYTTLVPLVIILTIAGIKEIIEDFKRHKADNAVNKKKTIVLRNGM--WHTIMWKEVAVGDIVKVLNGQYLPADMVLFSSSEPQGMCYVETANLDGETNLKIRQGLSHTTDMQTRDVLMKLSGRIECEGPNRHLYDFTGNLHLDGKSSVALGPDQILLRGTQLRNTQWVFGVVVYTGHDSKLMQNSTKAPLKRSNVEKVTNVQILVLFGILLVMALVSSVGALFWNGSHGGKS-WYIKKMDTNSDNFGYNLLTFIILYNNLIPISLLVTLEVVKYTQALFINWDMDMYYIENDTPAMARTSNLNEELGQVKYLFSDKTGTLTCNIMNFKKCSIAGVTYGHFPELAREQSSDDFCRMTSCTNDSCDFNDPRLLKNIEDQHPTAPCIQEFLTLLAVCHTVVPE-KDGDEIIYQASSPDEAALVKGAKKLGFVFTGRTP--YSVIIEAMGQEQTFGILNVLEFSSDRKRMSVIVRLPSGQLRLYCKGADNVIFERLS-KDSKYMEETLCHLEYFATEGLRTLCVAYADLSENEYEEWLKVYQEASIILKDRAQRLEECYEIIEKNLLLLGATAIEDRLQAGVPETIATLLKAEIKIWVLTGDKQETAINIGYSCRLVSQNMALILLKEDSLDATRAAITQHCTDLGN---LLGKENDVALIIDGHTLKYALSFEVRRSFLDLALSCKAVICCRVSPLQKSEIVDVVKKRVKAITLAIGDGANDVGMIQTAHVGVGISGNEGMQATNNSDYAIAQFSYLEKLLLVHGAWSYNRVTKCILYCFYKNVVLYIIELWFAFVNGFSGQILFERWCIGLYNVIFTALPPFTLGIFERSCTQESMLRFPQLYRITQNAEGFNTKVFWGHCINALVHSLILFWVPMKALEHDTPVTS-GHATDYLFVGNIVYTYVVVTVCLKAGLETTAWTKFSHLAVWGSMLIWLVFFGVYSTIWPTIPIAPDMKGQATMVLSSAYFWLGLFLVPTACLIEDVAWRAAKHTCKKTLLEEVQELETKSRVMGKAMLRDSN---------GKRMNERDRLIKRLSR-------KTPPTLFRTGSIQQCVSHGYAFSQEEHGAVTQ----EEIVRAYDTTKENSRKK-------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8I5ZQP3-1", "uniprot_id": "A0A8I5ZQP3_RAT", "id": "A0A8I5ZQP3-1", "name": "Phospholipid-transporting ATPase", "aln": "---------------------------------------------------------MLNGAGLDQAFKMSLPRRAR-------------------------IGA------------------SVGPVRSSAGYKKAED-------------EMSRATSVG---------------------------------------------------------------DQLEAPARIIYLNQSHLN---KFCDNRISTAKYSVLTFLPRFLYEQIRRAANAFFLFIALLQQIPDVSPTGRYTTLVPLVIILTIAGIKEIVEDFKRHKADNAVNKKKTIVLRNGM--WHTIMWKEVAVGDIVKVLNGQYLPADMVLFSSSEPQGMCYVETANLDGETNLKIRQGLSHTADMQTREVLMKLSGRIECEGPNRHLYDFTGTLHLDGKSSVALGPDQILLRGTQLRNTQWVFGVVVYTGHDTKLMQNSTKAPLKRSNVEKVTNVQILVLFGILLVMALVSSVGALFWNGSHGGKS-WYIKKMDTTSDNFGYNLLTFIILYNNLIPISLLVTLEVVKYTQALFINWDTDMYYIENDTPAMARTSNLNEELGQVKYLFSDKTGTLTCNIMNFKKCSIAGVTYGHFPELAREQSSDDFCRMTSCPSDSCDFNDPRLLKNIEDEHPTAPCIQEFLTLLAVCHTVVPE-KDGDEIIYQASSPDEAALVKGAKKLGFVFTGRTP--YSVIIEAMGQEQTFGILNVLEFSSDRKRMSVIVRMPSGQLRLYCKGADNVIFERLS-KDSKYMEETLCHLEYFATEGLRTLCVAYADLSENEYEEWLKVYQEASIILKDRAQRLEECYEIIEKNLLLLGATAIEDRLQAGVPETIATLLKAEIKIWVLTGDKQETAINIGYSCRLVSQNMALILLKEDSLDATRAAITQHCTDLGN---LLGKENDVALIIDGHTLKYALSFEVRRSFLDLALSCKAVICCRVSPLQKSEIVDVVKKRVKAITLAIGDGANDVGMIQTAHVGVGISGNEGMQATNNSDYAIAQFSYLEKLLLVHGAWSYNRVTKCILYCFYKNVVLYIIELWFAFVNGFSGQILFERWCIGLYNVIFTALPPFTLGIFERSCTQESMLRFPQLYKITQNAEGFNTKVFWGHCINALVHSLILFWVPMKALEHDTPLTS-GHATDYLFVGNIVYTYVVVTVCLKAGLETTAWTKFSHLAVWGSMLIWLVFFGVYSTFWPTIPIAPDMKGQATMVLSSAHFWLGLLLVPTACLIEDVAWRAAKHTCKKTLLEEVQELETKSRVMGKAMLRDSN---------GKRMNERDRLIKRLGR-------KTPPTLFRTGSIQQCVSHGYAFSQEEHGCVTQ----EEVVRCYDTTKEKSRKK-------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9NTI2-4", "uniprot_id": "AT8A2_HUMAN", "id": "Q9NTI2-4", "name": "Phospholipid-transporting ATPase IB", "aln": "---------------------------------------------------------MLNGAGLDKALKMSLPRRSR-------------------------IRS------------------SVGPVRSSLGYKKAED-------------EMSRATSVG---------------------------------------------------------------DQLEAPARTIYLNQPHLN---KFRDNQISTAKYSVLTFLPRFLYEQIRRAANAFFLFIALLQQIPDVSPTGRYTTLVPLIIILTIAGIKEIVEDFKRHKADNAVNKKKTIVLRNGM--WHTIMWKEVAVGDIVKVVNGQYLPADVVLLSSSEPQAMCYVETANLDGETNLKIRQGLSHTADMQTREVLMKLSGTIECEGPNRHLYDFTGNLNLDGKSLVALGPDQILLRGTQLRNTQWVFGIVVYTGHDTKLMQNSTKAPLKRSNVEKVTNVQILVLFGILLVMALVSSAGALYWNRSHGEKN-WYIKKMDTTSDNFGYNLLTFIILYNNLIPISLLVTLEVVKYTQALFINWDTDMYYIGNDTPAMARTSNLNEELGQVKYLFSDKTGTLTCNIMNFKKCSIAGVTYGHFPELAREPSSDDFCRMPPPCSDSCDFDDPRLLKNIEDRHPTAPCIQEFLTLLAVCHTVVPE-KDGDNIIYQASSPDEAALVKGAKKLGFVFTARTP--FSVIIEAMGQEQTFGILNVLEFSSDRKRMSVIVRTPSGRLRLYCKGADNVIFERLS-KDSKYMEETLCHLEYFATEGLRTLCVAYADLSENEYEEWLKVYQEASTILKDRAQRLEECYEIIEKNLLLLGATAIEDRLQAGVPETIATLLKAEIKIWVLTGDKQETAINIGYSCRLVSQNMALILLKEDSLDATRAAITQHCTDLGN---LLGKENDVALIIDGHTLKYALSFEVRRSFLDLALSCKAVICCRVSPLQKSEIVDVVKKRVKAITLAIGDGANDVGMIQTAHVGVGISGNEGMQATNNSDYAIAQFSYLEKLLLVHGAWSYNRVTKCILYCFYKNVVLYIIELWFAFVNGFSGQILFERWCIGLYNVIFTALPPFTLGIFERSCTQESMLRFPQLYKITQNGEGFNTKVFWGHCINALVHSLILFWFPMKALEHDTVLTS-GHATDYLFVGNIVYTYVVVTVCLKAGLETTAWTKFSHLAVWGSMLTWLVFFGIYSTIWPTIPIAPDMRGQATMVLSSAHFWLGLFLVPTACLIEDVAWRAAKHTCKKTLLEEVQELETKSRVLGKAVLRDSN---------GKRLNERDRLIKRLGR-------KTPPTLFRGSSLQQGVPHGYAFSQEEHGAVSQ----EEVIRAYDTTKKKSRKK-------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AB32TK55-1", "uniprot_id": "A0AB32TK55_DANRE", "id": "A0AB32TK55-1", "name": "Phospholipid-transporting ATPase", "aln": "----------------------------------------MYFNRRSKKIHSEGEQLVLTPLSQDSPLRQDQPLGPN-------------------------MCSRLADRFEKTSPPLFHHSNGAGPACSATGYRKAED-------------EMSGTTSQA---------------------------------------------------------------DPVDATARTVLLNRAQTT---KYCDNHVSTAKYGILTFLPRFLYEQIRRAANAFFLFIALMQQIPDVSPTGRYTTLVPLIFILTVAGIKEIIEDYKRHKADNTVNKKKTTVLRNGA--WQTIIWKQVAVGDIVKVTNGQHLPADMVIVSSSEPQAMCYTETSNLDGETNLKIRQGLSLTASFQSLEDLIALSGRLECEGPNRHLYDFTGTLRLDNHNPAPLGPDQVLLRGAQLRNTQWVVGIVVYTGHDSKLMQNSTKAPLKRSNVERVTNMQILVLFGILLVMALVSSIGAAIWNKQHTDEACWYLSRAGDISLNFAYNLLTFIILYNNLIPISLLVTLEVVKFTQALFINWDVEMYYAETDTPAMARTSNLNEELGQVKYLFSDKTGTLTCNVMHFKKCTIAGITYGHFPDLDCDRSMEDFSHLPSTSHNSTEFDDPALIQNIEKNHPTSPQICEFLTMMAVCHTVVPE-REDNQIIYQASSPDEGALVKGAKSLGFVFTARTP--HSVIIEARGKEQTYELLNVLEFSSNRKRMSVIVRTPTGNLRLYCKGADNVIFERLN-VTSQYKELTVAHLEQFATEGLRTLCFAYVDLEEGAYLEWLKEYNRISTVLKDRAQKLEECYELIEKNLLLLGATAIEDRLQAGVPETIATLMRADIKIWVLTGDKQETAINIGYSCRLVSHGMSLIIVNEDSLDATRATLTAHCSSLGD---SLRKENELALIIDGQTLKYALSFEVRQAFLDLALSCKAVICCRVSPLQKSEIVDMVKKHVKAITLAIGDGANDVGMIQTAHVGVGISGNEGMQATNSSDYSIAQFSYLEKLLLVHGAWSYNRVTKCILYCFYKNVVLYIIELWFAFVNGFSGQILFERWCIGLYNVIFTALPPFTLGIFDRPCSQQNMIRFPQLYRITQNAEGFNTKVFWGHCINALIHSIILFWFPLKALEHDTPFDN-GNSVDYLFVGNIVYTYVVVTVCLKAGMETTAWTRFSHLAVWGSMVLWMLFFAVYSAIWPTIPIAPDMLGQAGRVMQCWSFWLGLILVPTACLLKDVVWNAGRRTVRKTLLEEVQELEARAVDPGAAVLRDAS---------GRSLNERAHLLTRVFR-------KTPSSVGRSNSVQQTVSHGYAFSQEEHGVVSQ----SQVVRSYDTTRQRPSL--------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "B7YZF8-1", "uniprot_id": "B7YZF8_DROME", "id": "B7YZF8-1", "name": "Phospholipid-transporting ATPase", "aln": "---------------MSGSYQRQSLELRSPDHGSVDDPDGCLRNHLGSSASQRRRQQRIAQQRQDSWFRHSMPPAINRDFESLEHLTPRASDGLDEQLAASVSHSVHSGGSVTLCGPPDHSSIHLNSANSNLGFIDSDTPNTPVTPVSGLQPPASVSTSVGGTLSSRRRSSNRKDSKGSILSRQSGKSRVSLLAQRGLRMTASFLRRKRTEYEDDEDFTSSAGYDADDGERRIINLNGPQPT---KYGNNRITTAKYSFISFLPAFLFEQFRRYSNCFFLLIAILQQIPEVSPTGRYTTLVPLMFILSVSAIKEIIEDIKRHRADNEINHRSIERLDSGS--WCTVRWSELTVGDIIKVGINTFFPADLILLSSSEPQAMCFIETANLDGETNLKIRQALPATAELLETKDLQRLEGRIECELPNRHLYEFNGVLRETGKPPAALGNDQVLQRGAILRNTAWVFGIVVYSGQETKLMKNSTSAPLKRSTVDKLTNTQILMLFMILISLCIISGLCNLFWTREHSETD-WYLGLTDFKTKSLGYNLLTFFILYNNLIPISLQVTLELVRFLQAIFINYDIEMYHEESNTPAMARTSNLNEELGMVKYIFSDKTGTLTQNVMEFKKCSIAGYVY------TAERTPE----------------ESQLVQNILGRHETSAVIEEFLELLSVCHTVIPERKENGNMIYHAASPDERALVEGAQKFGYIFDTRTP--KYVEINALGVRKRYEVLNVLEFTSSRKRMSLIVRTPENKIKLFCKGADTVIYERLAPQGQAFREQTLRHLEEFASDGLRTLCLAVADIRPDVYQEWSQTFDKASVALQNRESKLEDAANLIENNLRLLGATAIEDRLQDGVPETIASLLDAGIYIWVLTGDKQETAINIGYSCRLISHSMDIIILNEESLDATREVIHRHYGEFKS---SSAKDANVALVIDGTTLKYALSCDLRNDFQDLCILCRVVICCRVSPMQKAEVVEMVTQSTNAVTLAIGDGANDVAMIQKANVGIGISGVEGLQAACASDYSIAQFRYLQRLLLVHGAWNYARISKLILYSFYKNVCLYVIELWFAVYSGWSGQILFERWTIGLYNVLFTAMPPFAMGLFEKFCTAETMIRYPMLYKTSQNAKLFNVKVFWIWIFNALLHSVFLFWLPLAAYTKEVIWSD-GKTSDYLLMGNLVYTYVIVTVCLKAGLITNSWTWLTHLAIWGSIVLWFGFLLIYSHVWPMFKFASNFRGMDIQLLSTPVFYFCLMLVPITTLLIDVICKLVHNTVFKTLTEAVRETEIRRSDISEVMNEPRSSDSGFGYALGKLIRSSHILISHDHH-------PVSESSRTSNLRVENLEMEADTEQQQQSRQRQKWRGGQVATGVARSARNSTTSPITATLHM-----", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P39524-1", "uniprot_id": "ATC3_YEAST", "id": "P39524-1", "name": "Phospholipid-transporting ATPase DRS2", "aln": "MNDDRETPPKRKPGEDDTLFDIDFLDDTTSHSGSRSKVTNSHANANYIPPSHVLPEETIDLDADDDNIENDVHENLFMSNNHDDQTSWNANRFDSDAYQPQSLRAVKPPGLFARFGNGLKNAFTFKRKKGPESFEMNHYNAVTNNELDDNYLDSRNKFNIKILFNRYILRKN-------------------------------------------------VGDAEGNGEPRVIHINDSLANSSFGYSDNHISTTKYNFATFLPKFLFQEFSKYANLFFLCTSAIQQVPHVSPTNRYTTIGTLLVVLIVSAMKECIEDIKRANSDKELNNSTAEIFSEAHDDFVEKRWIDIRVGDIIRVKSEEPIPADTIILSSSEPEGLCYIETANLDGETNLKIKQSRVETAKFIDVKTLKNMNGKVVSEQPNSSLYTYEGTMTLNDRQ-IPLSPDQMILRGATLRNTAWIFGLVIFTGHETKLLRNATATPIKRTAVEKIINRQIIALFTVLIVLILISSIGNVIMSTADAKHLSYLYLEGTNKAGLFFKDFLTFWILFSNLVPISLFVTVELIKYYQAFMIGSDLDLYYEKTDTPTVVRTSSLVEELGQIEYIFSDKTGTLTRNIMEFKSCSIAGHCYIDKIPEDKTATVEDGIEVG------YRKFDDLKKKLNDPSDEDSPIINDFLTLLATCHTVIPEFQSDGSIKYQAASPDEGALVQGGADLGYKFIIRKPNSVTVLLEETGEEKEYQLLNICEFNSTRKRMSAIFRFPDGSIKLFCKGADTVILERLDDEANQYVEATMRHLEDYASEGLRTLCLAMRDISEGEYEEWNSIYNEAATTLDNRAEKLDEAANLIEKNLILIGATAIEDKLQDGVPETIHTLQEAGIKIWVLTGDRQETAINIGMSCRLLSEDMNLLIINEETRDDTERNLLEKINALNEHQLSTHDMNTLALVIDGKSLGFALEPELEDYLLTVAKLCKAVICCRVSPLQKALVVKMVKRKSSSLLLAIGDGANDVSMIQAAHVGVGISGMEGMQAARSADIAVGQFKFLKKLLLVHGSWSYQRISVAILYSFYKNTALYMTQFWYVFANAFSGQSIMESWTMSFYNLFFTVWPPFVIGVFDQFVSSRLLERYPQLYKLGQKGQFFSVYIFWGWIINGFFHSAIVFIGTILIYRYGFALNMHGELADHWSWGVTVYTTSVIIVLGKAALVTNQWTKFTLIAIPGSLLFWLIFFPIYASIFPHANISREYYGVVKHTYGSGVFWLTLIVLPIFALVRDFLWKYYKRMYEPETYHVIQEMQKYNISDSRPHVQQFQNAIRKVRQVQRMKKQRGFAFSQAEEGGQEKIVRMYDTTQKRGKYGELQDASANPFNDNNGLGSNDFESAEPFIENPFADGNQNSNRFSSSRDDISFDI", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . :. * : :* . . : :*:::*:**.. :*** **:::: : :* *** : :**:*.****.****: .*:.:* ::.:** :** ** .:*: :*: . : .. : * :: ****::* :*** ::.*****:.:*: **:**********:*. *:.: . * :.* : .* ** ** : * : .: .*. **:: **: **** *:.*:*:::*:::**::*:* :*:**: *::: * **: ** :*: : ::*. . . : : : ::*** **:.**:**** **:*:::: **::*. * ::*: .:**::.***.* **** ::*:********* *:*.**.*:*** * : : : : . :. * :** :::.****:** :....: *:*:**** ***:*. .:*: * *.* * :: * .: : :**: **.* ***** *.* * . ::*:*****.** *** . : * *: *** :*::******.* *: . * ** . ::. : *.:* .:*::. ::**:** *:*******:** ****** :* * * *******:******** ****:*..* :::::*:: * *. : : : . . :**:*** :* :**. ::. : :. *:.********:**: :*.:*.: .:: **********.*** *:**:**** **:**: :* ::.** :*::******:*.* *:: ***.****. **: ::*:.. ..:*** ::* * :.:**::**. ***.:*:*:: : . : *:* **: *:.: *.. :** :*.:.** ::* .: *. *: * *** :: * **.: *. ** :: :*: **:: *: *: :*: .:* :: : * *:: *:::* *: *. . :. . ::* : . . . : .. :.: . : . : ::::. : : : . ", "identical_positions": 385, "similar_positions": 363, "identity": "27.29%" }, { "cls_id": "homologset.agr.MGI:1354713", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P39002-1", "uniprot_id": "LCF3_YEAST", "id": "P39002-1", "name": "Long-chain-fatty-acid--CoA ligase 3", "aln": "------------------------MSEQHSVAVGKAANEHETAPRRNVRVK-------------------------KRPLIRPLNSSASTLYEFALECFNKGGKRDGMAWRDVIEIHETKKTIVRKVDGKDKSIEKTWLYYEMSPYKMMTYQELIWVMHDMGRGLAKIGIKPNGEHKFHIFASTSHKWMKIFLGCISQGIPVVTAYDTLGESGLIHSMVETESAAIFTDNQLLA-KMIVPLQSAKDIKFLIHNEPIDPNDRRQNGKLYKAAKDAINKIREVRPDIKIYSFEEVVKIGKKSKDE-VKLHPPEPKDLACIMYTSGSISAPKGVVLTHYNIVSGIAGVGHNVFGWIGSTDRVLSFLPLAHIFELVFEFEAFYWNGILGYGSVKTLTNTS---TRNCKGDLVEFKPTIMIGVAAVWETVRKAILEKISDLTPVLQKIFWSAY----SMKEKSVPCTGFLSRMVFKKVRQATGGHLKYIMNGGSAISIDAQKFFSIVLCP-MIIGYGLTETVANACVLEPDHFEYGIVGDLVGSVTAKLVDVKDLGYYAKNN---QGELLLKGAPVCSEYYKNPIETAVSFTY----DGWFRTGDIVEWTPKGQLKIIDRRKNLVKTLNGEYIALEKLESVYRSNSYVKNICVYADESRVKPVGIVVPNPGPLSKFAVKLRIMKKGE---DIENYIHDKALRNAVFKEMIATAKSQGLVGIELLCGIVFFDEEWTPENGFVTSAQKLKRREILAAVKSEVERVYKENS", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P47912-1", "uniprot_id": "LCF4_YEAST", "id": "P47912-1", "name": "Long-chain-fatty-acid--CoA ligase 4", "aln": "------------------------MTEQYSVAVGEAANEHETAPRRNIRVK-------------------------DQPLIRPINSSASTLYEFALECFTKGGKRDGMAWRDIIDIHETKKTIVKRVDGKDKPIEKTWLYYELTPYITMTYEEMICVMHDIGRGLIKIGVKPNGENKFHIFASTSHKWMKTFLGCMSQGIPVVTAYDTLGESGLIHSMVETDSVAIFTDNQLLS-KLAVPLKTAKNVKFVIHNEPIDPSDKRQNGKLYKAAKDAVDKIKEVRPDIKIYSFDEIIEIGKKAKDE-VELHFPKPEDPACIMYTSGSTGTPKGVVLTHYNIVAGIGGVGHNVIGWIGPTDRIIAFLPLAHIFELTFEFEAFYWNGILGYANVKTLTPTS---TRNCQGDLMEFKPTVMVGVAAVWETVRKGILAKINELPGWSQTLFWTVY----ALKERNIPCSGLLSGLIFKRIREATGGNLRFILNGGSAISIDAQKFLSNLLCP-MLIGYGLTEGVANACVLEPEHFDYGIAGDLVGTITAKLVDVEDLGYFAKNN---QGELLFKGAPICSEYYKNPEETAAAFTD----DGWFRTGDIAEWTPKGQVKIIDRKKNLVKTLNGEYIALEKLESIYRSNPYVQNICVYADENKVKPVGIVVPNLGHLSKLAIELGIMVPGE---DVESYIHEKKLQDAVCKDMLSTAKSQGLNGIELLCGIVFFEEEWTPENGLVTSAQKLKRRDILAAVKPDVERVYKENT", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P30624-1", "uniprot_id": "LCF1_YEAST", "id": "P30624-1", "name": "Long-chain-fatty-acid--CoA ligase 1", "aln": "------------------------MVAQYTVPVGKAANEHETAPRRNYQCR-------------------------EKPLVRPPNTKCSTVYEFVLECFQKNKNSNAMGWRDVKEIHEESKSVMKKVDGKETSVEKKWMYYELSHYHYNSFDQLTDIMHEIGRGLVKIGLKPNDDDKLHLYAATSHKWMKMFLGAQSQGIPVVTAYDTLGEKGLIHSLVQTGSKAIFTDNSLLP-SLIKPVQAAQDVKYIIHFDSISSEDRRQSGKIYQSAHDAINRIKEVRPDIKTFSFDDILKLGKESCNE-IDVHPPGKDDLCCIMYTSGSTGEPKGVVLKHSNVVAGVGGASLNVLKFVGNTDRVICFLPLAHIFELVFELLSFYWGACIGYATVKTLTSSS---VRNCQGDLQEFKPTIMVGVAAVWETVRKGILNQIDNLPFLTKKIFWTAYNTKLNMQRLHIPGGGALGNLVFKKIRTATGGQLRYLLNGGSPISRDAQEFITNLICP-MLIGYGLTETCASTTILDPANFELGVAGDLTGCVTVKLVDVEELGYFAKNN---QGEVWITGANVTPEYYKNEEETSQALTS----DGWFKTGDIGEWEANGHLKIIDRKKNLVKTMNGEYIALEKLESVYRSNEYVANICVYADQSKTKPVGIIVPNHAPLTKLAKKLGIMEQKDSSINIENYLEDAKLIKAVYSDLLKTGKDQGLVGIELLAGIVFFDGEWTPQNGFVTSAQKLKRKDILNAVKDKVDAVYSSS-", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "Q9QUJ7-1", "uniprot_id": "ACSL4_MOUSE", "id": "Q9QUJ7-1", "name": "Long-chain-fatty-acid--CoA ligase 4", "aln": "MNLKLNVLTIILLPVHLLITIYSALIFIPWYFLTNAKKKNAMAKRIKAKPT----------------------SDKPGSPYRSVTHFDSLAVIDIPG-ADTLDKLFDHAVAKFGKKDSLGTREILSEENEMQPNGKVFKKLILGNYKWINYLEVNCRVNNFGSGLTALGLKPK--NTIAIFCETRAEWMIAAQTCFKYNFPLVTLYATLGREAVVHGLNESEASYLITSVELLESKLKAALVDINCVKHIIYVDN------------------KTINRAEYPEGLEIHSMQSVEELGAKPENLSVPPSRPTPSDMAIVMYTSGSTGRPKGVMMHHSNLIAGMTGQ-CERIPGLGPKDTYIGYLPLAHVLELTAEISCFTYGCRIGYSSPLTLSDQSSKIKKGSKGDCTVLKPTLMAAVPEIMDRIYKNVMSKVQEMNYVQKTLFKIGYDYKLEQIKKGYDAP-LCNLILFKKVKALLGGNVRMMLSGGAPLSPQTHRFMNVCFCCPIGQGYGLTESCGAGTVTEVTDYTTGRVGAPLICCEIKLKDWQEGGYTVHDKPNPRGEIVIGGQNISMGYFKNEEKTAEDYCVDENGQRWFCTGDIGEFHPDGCLQIIDRKKDLVKLQAGEYVSLGKVEAALKNCPLIDNICAFAKSDQSYVISFVVPNQKKLTLLAQQK-----GVEG-SWVDICNNPAMEAEILKEIREAANAMKLERFEIPIKVRLSPEPWTPETGLVTDAFKLKRKELKNHYLKDIERMYGGK-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O35547-1", "uniprot_id": "ACSL4_RAT", "id": "O35547-1", "name": "Long-chain-fatty-acid--CoA ligase 4", "aln": "MKLKLNVLTIVLLPVHLLITIYSALIFIPWYFLTNAKKKNAMAKRIKAKPT----------------------SDKPGSPYRSVTHFDSLAVIDIPG-ADTLDKLFDHAVAKFGKKDSLGTREILSEENEMQPNGKVFKKLILGNYKWINYLEVNCRVNNFGSGLTALGLKPK--NTIAIFCETRAEWMIAAQTCFKYNFPLVTLYATLGKEAVVHGLNESEASYLITSVELLESKLKAALLDINCVKHIIYVDN------------------KTINRAEYPEGLEIHSMQSVEELGSKPENSSIPPSRPTPSDMAIVMYTSGSTGRPKGVMMHHSNLIAGMTGQ-CERIPGLGPKDTYIGYLPLAHVLELTAEISCFTYGCRIGYSSPLTLSDQSSKIKKGSKGDCTVLKPTLMAAVPEIMDRIYKNVMSKVQEMNYIQKTLFKIGYDYKLEQIKKGYDAP-LCNLILFKKVKALLGGNVRMMLSGGAPLSPQTHRFMNVCFCCPIGQGYGLTESCGAGTVTEVTDYTTGRVGAPLICCEIKLKDWQEGGYTVHDKPNPRGEIVIGGQNISMGYFKNEEKTAEDYSVDENGQRWFCTGDIGEFHPDGCLQIIDRKKDLVKLQAGEYVSLGKVEAALKNCPLIDNICAFAKSDQSYVISFVVPNQKKLTLLAQQK-----GVEG-SWVDICNNPAMEAEILKEIREAANAMKLERFEIPIKVRLSPEPWTPETGLVTDAFKLKRKELKNHYLKDIERMYGGK-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O60488-1", "uniprot_id": "ACSL4_HUMAN", "id": "O60488-1", "name": "Long-chain-fatty-acid--CoA ligase 4", "aln": "MKLKLNVLTIILLPVHLLITIYSALIFIPWYFLTNAKKKNAMAKRIKAKPT----------------------SDKPGSPYRSVTHFDSLAVIDIPG-ADTLDKLFDHAVSKFGKKDSLGTREILSEENEMQPNGKVFKKLILGNYKWMNYLEVNRRVNNFGSGLTALGLKPK--NTIAIFCETRAEWMIAAQTCFKYNFPLVTLYATLGKEAVVHGLNESEASYLITSVELLESKLKTALLDISCVKHIIYVDN------------------KAINKAEYPEGFEIHSMQSVEELGSNPENLGIPPSRPTPSDMAIVMYTSGSTGRPKGVMMHHSNLIAGMTGQ-CERIPGLGPKDTYIGYLPLAHVLELTAEISCFTYGCRIGYSSPLTLSDQSSKIKKGSKGDCTVLKPTLMAAVPEIMDRIYKNVMSKVQEMNYIQKTLFKIGYDYKLEQIKKGYDAP-LCNLLLFKKVKALLGGNVRMMLSGGAPLSPQTHRFMNVCFCCPIGQGYGLTESCGAGTVTEVTDYTTGRVGAPLICCEIKLKDWQEGGYTINDKPNPRGEIVIGGQNISMGYFKNEEKTAEDYSVDENGQRWFCTGDIGEFHPDGCLQIIDRKKDLVKLQAGEYVSLGKVEAALKNCPLIDNICAFAKSDQSYVISFVVPNQKRLTLLAQQK-----GVEG-TWVDICNNPAMEAEILKEIREAANAMKLERFEIPIKVRLSPEPWTPETGLVTDAFKLKRKELRNHYLKDIERMYGGK-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A0B4KFE4-1", "uniprot_id": "A0A0B4KFE4_DROME", "id": "A0A0B4KFE4-1", "name": "long-chain-fatty-acid--CoA ligase", "aln": "--MDSFWVQSAIGAIKAIAFVYDIITLPVYLVLQKPWKRRQDSRRVKAKPINQKMLVDESKYAPDDIEAKIVRNDDNELTYRTTDPPRDVHVKMLQENIDTLEKVFNYVAKTYTSKRCLGTRQILSEEDEVQQNGRVFKKYNLGDYKWKTFTEAERTAANFGRGLRELGQKPR--ENIVIFAETRAEWMIAAHGCFKQAMPIVTVYATLGDDGVAHCITETEVTTVITSHDLLP-KFKTLLDKCPLVKTIIYIEDQL----------------QKTETTGFKEGVKILPFNQVVKTGQDSKFEHVPPKG---DDIAIIMYTSGSTGTPKGVLLSHKNCIATMKGF-VDMVP-IYPDDVLIGFLPLAHVFELVAESVCLMTGVPIGYSTPLTLIDTSSKIKRGCKGDATVLKPTCMTSVPLILDRISKGINDKVNSGSAFKKSLFKFLYQYKVKWVQRGYKTP-LIDKLVFKKVAKLMGGKVRIIMSGGAPLSADTHEQIKTCLCLELIQGYGLTETTSGATVMDYRDMTYGRTGGPLTVCDIRLVNWEEGNYRVTNKPYPQGEVLIGGECVSQGYYKLPGKTNEDFFE-EDGQRWFKTGDIGEIQADGVLKIIDRKKDLVKLQAGEYVSLGKVESELKTCGIIENICVYGDPTKQYTVALVVPNQNHLEELAQKH-----GLGDKSFEELCSSPIIEKAILKEIAEHARKCKLQKYEVPAAITLCKEVWSPDMGLVTAAFKLKRKDIQDRYQHDINRMYAS--", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q6IQU4-1", "uniprot_id": "CWC15_DANRE", "id": "Q6IQU4-1", "name": "Protein CWC15 homolog", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------MTTAARPTFEPARGGRGKG-----EGDLSALSKQYSSRDLPGHTKIKYRQPTQDAPEEVRARDFRRELEERERAAVK--------------------------------------------------------------------------------------------------GRDRGAREHTTSSSSSSSSS--------SSKRPRLDQIPAAN----------------LDADDPLTDDEDD----SGSDSDSDDDTAALLAELEKIKRERAEEQERKEREQKAEEE----------------------------RIRMENILSGNPLLNLAGQQQQQQQQQQQTQTKNTFSVKRRWDDDVVFKN-----------------------------------------------------------------------------CAKGVDESRKEKRFVNDTLRSEFHKKFMEKYVK--------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . * * : . . . * : . : : : : . :*. . : . : :* *: :. * . ....* ..: : : : : : . : :: .*: : * . : :. : :. : .: * . . :.:: * :*: ", "identical_positions": 13, "similar_positions": 61, "identity": "1.7%" }, { "cls_id": "homologset.agr.MGI:1354721", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "F1LZW6-1", "uniprot_id": "S2513_RAT", "id": "F1LZW6-1", "name": "Electrogenic aspartate/glutamate antiporter SLC25A13, mitochondrial", "aln": "--------------------------------MAAAKVALTKRADPAELKAIFLKYASIEKNGEFFMSPHDFVTRYLN-----------IFGESQPNPKTVELLSGVVDQTKDGLISFQEFVAFESVLCAPDALFMVAFQLFDKAGKGEVTFEDVRQVFG------------QTTIHQHIPFNWDSEFVQLHFGKERKRHLTYAEFT---------------QFLLEIQLEHAKQAFVQRDNAKTGKVTAIDFRDIMVTIRPHVLTP-------FVEECLVAAAGGTRSHQVSFSYFNGFNS-----------------------LLNNMELIRKIYSTLAGSR-------KDVEVTKEEFALAAQKFG-------QVTPMEVDILFQLADLYEPR-------------------------------------------------------------------------------GRMTLADIERIAPLEEGMLPFN--------LAEAQRQQKASGDAARPFLLQLAESAYRFGLGSIAGAVGATAVYPIDLVKTRMQNQRSTGSFVGELMYKNSFDCFKKVLRYEGFFGLYRGLLPQLLGVAPEKAIKLTVNDFVRDKFMHKDGSVPLLAEIFAGGCAGGSQVIFTNPLEIVKIRLQVAGEITTG----PRVSALSVVRDLGFFGIYKGAKACFLRDIPFSAIYFPCYAHVKASFANED-------GQVSPGSLLLAGAIAGMPAASLVTPADVIKTRLQVAARAGQTTYSGVTDCFRKILREEGPKALWKGAGARVFRSSPQFGVTLLTYELLQRWFYVDFGGVKPV------------GSE------LVPKSRITLPAPNPDHVGGYK---LAVATFAGIENKFGLYLPLFKP-SASTSKVTAVGS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9QXX4-1", "uniprot_id": "S2513_MOUSE", "id": "Q9QXX4-1", "name": "Electrogenic aspartate/glutamate antiporter SLC25A13, mitochondrial", "aln": "--------------------------------MAAAKVALTKRADPAELKAIFLKYASIEKNGEFFMSPHDFVTRYLN-----------IFGESQPNPKTVELLSGVVDQTKDGLISFQEFVAFESVLCAPDALFMVAFQLFDKAGKGEVTFEDVKQIFG------------QTTIHQHIPFNWDSEFVQLHFGKERKRHLTYAEFT---------------QFLLEIQLEHAKQAFVQRDNAKTGKVSAIDFRDIMVTIRPHVLTP-------FVEECLVAAAGGTRSHQVSFSYFNGFNS-----------------------LLNNMELIRKIYSTLAGNR-------KDVEVTKEEFALAAQKFG-------QVTPMEVDILFQLADLYEPR-------------------------------------------------------------------------------GRMTLADIERIAPLEEGMLPFN--------LAEAQRQQKASGDAARPFLLQLAESAYRFGLGSIAGAVGATAVYPIDLVKTRMQNQRSTGSFVGELMYKNSFDCFKKVLRYEGFFGLYRGLLPQLLGVAPEKAIKLTVNDFVRDKFMHKDGSVPLLAEIFAGGCAGGSQVIFTNPLEIVKIRLQVAGEITTG----PRVSALSVVRDLGFFGIYKGAKACFLRDIPFSAIYFPCYAHVKASFANED-------GQVSPGSLLLAGAIAGMPAASLVTPADVIKTRLQVAARAGQTTYNGVTDCFRKILREEGPKALWKGVAARVFRSSPQFGVTLLTYELLQRWFYVDFGGVKPV------------GSE------PVPKSRITLPAPNPDHVGGYK---LAVATFAGIENKFGLYLPLFKP-SASTSKVTAGDS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9UJS0-1", "uniprot_id": "S2513_HUMAN", "id": "Q9UJS0-1", "name": "Electrogenic aspartate/glutamate antiporter SLC25A13, mitochondrial", "aln": "--------------------------------MAAAKVALTKRADPAELRTIFLKYASIEKNGEFFMSPNDFVTRYLN-----------IFGESQPNPKTVELLSGVVDQTKDGLISFQEFVAFESVLCAPDALFMVAFQLFDKAGKGEVTFEDVKQVFG------------QTTIHQHIPFNWDSEFVQLHFGKERKRHLTYAEFT---------------QFLLEIQLEHAKQAFVQRDNARTGRVTAIDFRDIMVTIRPHVLTP-------FVEECLVAAAGGTTSHQVSFSYFNGFNS-----------------------LLNNMELIRKIYSTLAGTR-------KDVEVTKEEFVLAAQKFG-------QVTPMEVDILFQLADLYEPR-------------------------------------------------------------------------------GRMTLADIERIAPLEEGTLPFN--------LAEAQRQ-KASGDSARPVLLQVAESAYRFGLGSVAGAVGATAVYPIDLVKTRMQNQRSTGSFVGELMYKNSFDCFKKVLRYEGFFGLYRGLLPQLLGVAPEKAIKLTVNDFVRDKFMHKDGSVPLAAEILAGGCAGGSQVIFTNPLEIVKIRLQVAGEITTG----PRVSALSVVRDLGFFGIYKGAKACFLRDIPFSAIYFPCYAHVKASFANED-------GQVSPGSLLLAGAIAGMPAASLVTPADVIKTRLQVAARAGQTTYSGVIDCFRKILREEGPKALWKGAGARVFRSSPQFGVTLLTYELLQRWFYIDFGGVKPM------------GSE------PVPKSRINLPAPNPDHVGGYK---LAVATFAGIENKFGLYLPLFKP-SVSTSKAIGGGP", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VA73-1", "uniprot_id": "CMC_DROME", "id": "Q9VA73-1", "name": "Electrogenic aspartate/glutamate antiporter Aralar, mitochondrial", "aln": "--------------MPMHIPFPFNWIPTLPVARCQESPSLLKRAGTEKLREVFLKYASIQKNGEHYMTSEDFVRKFLG-----------LFSESAFNDESVRLLANIADTSKDGLISFSEFQAFEGLLCTPDALYRTAFQLFDRKGNGTVSYADFADVVQ------------KTELHSKIPFSLDGPFIKRYFGDKKQRLINYAEFT---------------QLLHDFHEEHAMEAFRSKDPAGTGFISPLDFQDIIVNVKRHLLTP-------GVRDNLVSVTEG---HKVSFPYFIAFTS-----------------------LLNNMELIKQVYLHATEGS-------RTDMITKDQILLAAQTMS-------QITPLEIDILFHLAGAVHQA-------------------------------------------------------------------------------GRIDYSDLSNIAP-EHYTKHMT--------HRLAEIKAVESP-ADRSAFIQVLESSYRFTLGSFAGAVGATVVYPIDLVKTRMQNQR-AGSYIGEVAYRNSWDCFKKVVRHEGFMGLYRGLLPQLMGVAPEKAIKLTVNDLVRDKLTDKKGNIPTWAEVLAGGCAGASQVVFTNPLEIVKIRLQVAGEIASG----SKIRAWSVVRELGLFGLYKGARACLLRDVPFSAIYFPTYAHTKAMMADKD-------GYNHPLTLLAAGAIAGVPAASLVTPADVIKTRLQVVARSGQTTYTGVWDATKKIMAEEGPRAFWKGTAARVFRSSPQFGVTLVTYELLQRLFYVDFGGTQPK------------GSEAHKITTPLEQAAASVTTENVDHIGGYR---AAVPLLAGVESKFGLYLPRFGRGVTAASPSTATGS", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q12482-1", "uniprot_id": "AGC1_YEAST", "id": "Q12482-1", "name": "Mitochondrial aspartate-glutamate transporter AGC1", "aln": "MEQINSNSRKKKQQLEVFKYFASVLTKEDKPISISNGMLDMPTVNSSKLTAGNGKPDTEKLTGELILTYDDFIELISSSKTIYSKFTDHSFNLNQIPKNVFGCIFFAIDEQNKGYLTLNDWFYFNNLLEYDNYHLIILYEFFRKFDVENLKAKQKKELGSSSFNLKAADDRIKSINYGNRFLSFDDLLLNLNQFKDTIRLLHESIDDNFVKDNKLLLDWNDFRFLKFYKCYHENEEYLSLNSLVTILQNDLKNEKIFIGFDRLAQMDSQGHRLALSKNQLTYLLRLFYSHRVSADIFSSLNLSNTELLKADNNSIPYNVFKDIFYLFQNFDLLNQIFHKYVTENNLNEQDIREQIVTKNDFMTVLNAQYNKVNNIIEFSPSQINLLFSIVANSKENRRLRKRNQDRDDELLNDHHYDSDIDFFIHNEYLHGVSRSRKNLESFNDYYHDLSDGFDQDSGVKKASKASTGLFESVFGGKKDKATMRSDLTIEDFMKILNPNYLNDLVHQMELQKNQNESLYINYYFYPIFDSLYNFSLGSIAGCIGATVVYPIDFIKTRMQAQR------SLAQYKNSIDCLLKIISREGIKGLYSGLGPQLIGVAPEKAIKLTVNDFMRNRLTDKNGKLSLFPEIISGASAGACQVIFTNPLEIVKIRLQVQSDYVGENIQQANETATQIVKKLGLRGLYNGVAACLMRDVPFSAIYFPTYAHLKKDLFDFDPNDKTKRNRLKTWELLTAGAIAGMPAAFLTTPFDVIKTRLQIDPRKGETKYNGIFHAIRTILKEESFRSFFKGGGARVLRSSPQFGFTLAAYELFKGFIPSPDNKLKSREGRKRFCIDDDAGNEETVVHSNGELPQQKFYSDDRKHANYYYKSCQIAKTFIDLDNNFSRFDSSVYKNFQEHLRSING--", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ... :* * : : .** :: .**: . *. . : . : * :.* :::.:: *:.:* : :::* : . :. : :: :: : : :. *. ::: .. * : : ::* : * : : . : * . :. ..*:: . .: *. *:** * .:. *::*::*:.::: . : :**::: . : :.:* ::::** :. . *: : : . *. :. : . . : : :* *.* ***.**.:***.*****::***** ** . *:** **: *:: **: *** ** ***:**************::*::: .*.*.:. .*:::*..**..**:************** .: . .. * .:*:.**: *:*:*. **::**:******** *** * : : * . . ** ******:*** *.** ********: .* *:*.*.*: .. :.*: **. ::::** .***:*******.** :***:: : . :. *.* . .. : : .* . * . : .::.:*. : . . ", "identical_positions": 185, "similar_positions": 215, "identity": "20.33%" }, { "cls_id": "homologset.agr.MGI:1354723", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q3TRM4-1", "uniprot_id": "PLPL6_MOUSE", "id": "Q3TRM4-1", "name": "Patatin-like phospholipase domain-containing protein 6", "aln": "---------MGTPSHELNTTSSGAEVIQK-------TLEEGLGRRICVAQPVPFVPQVLGVMIGAGVAVLVTAVLILL---VVRRLRVQKTPAPEGPRYRFRKRDKVLFYGRKIMRKVSQSTSSLVDTSVSTTSRPRMKKKLKMLNIAKKILRIQKETPTLQRK--EPPPS------------VLEADLTEGDLANSHLPSEVLYMLKNVRVLGHFEKPLFLELCRHMVFQRLGQGDYVFRPGQPDASIYVVQDGLLELCLPGPD------------------------------------------------------------GKECVVKEVVPGDSVNSLLSILDVITGHQHPQR--------------------------------------------------TVSARAARDSTVLRLPVEAFSAVFTKYPESLVRVVQIIMVRLQRVTFLALHNYLGLTNELFSHEIQPLRLFPSPG---------------------LPTRTSPVRGSKRVVSTSGTEDTSKETSGRPLDSIGAPLPGPAGDPVKPTSLEAPPAP--------------------LLSRCISMPVDISGLQGGPRSDFDMAYERGRISVSLQEEASGGPQTASPR----ELREQPAGACEYSYCEDESATGGCPFGPYQGRQ-----------------------TSSIFEAAKRELAKLMRIE--DPSLLNS----------------------------------------------------------------------------------------------------RVLLHHAKAGTIIARQG-DQDVSLHFVLWGCLHVYQRMIDKA-----------------------EEVCLFVAQPGELVGQLAVLTGEPLIFTLRAQRDCTFLRISKSHFYEIMRAQPSVVLSAAHTVAARMSPFVRQMDFAIDWTAVEAGRALYRQGDRSDCTYIVLNGRLRSVIQRGSG-----------KKELVGEYGRGDLIGVVEALTRQPRATTVHAVRDTELAKLPEGTLGHIKRRYPQVVTRLIHLLSQKILGN-----------------LQQLQGPFP-GSGLSVPQHS---ELTNPASNLSTVAILPVCAEVPMMAFTLELQHALQAIG-PTLLLNSDVIRALLGASALDSIQEFRLSGWLAQQEDAHRIVLYQTDTSLTP-WTVRCLRQADCILIVGLG-DQEPTVGQLEQMLENTAVRALKQLVLLHREEG-PGPTRTVEWLNMRSWCSGHLHLRCPRR---------------------------LFSRRSPAKLHELYEKVFSRRAD-------------------RHSDFSRLARVLTGNTIALVLGGGGARGCSHIGVLKALEEAGVPVDLVGGTSIGSFIGALYAEERSASRTKQRAREWAKSMTSVLEPVLDLTYPVTSMFTGSAFNRSIHRVFQDKQIEDLWLPYFNVTTDITASAMRVHKDGSLWRYVRASMTLSGYLPPLCDPKDGHLLMDGGYINNLPADIARSMGAKTVIAIDVGSQDETDLSTYGDSLSGWWLLWKRLNPWADKVKVPDMAEIQSRLAYVSCVRQLEVVKSSSYCEYLRPSIDCFKTMDFGKFDQIYDVGYQYGKAVFGGWTRGEVIEKMLTDRRSTDLNESRRADILAFPSSGFTDLAEIVSRI-EPPTSYVSDGCADGEESD---------------------------CLTEYEEDAGPDCSRDEGGSPE--GASPSTA-SEVE---------------------------EEKSTLRQRRFLPQETPSSVADA------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "M0R715-1", "uniprot_id": "M0R715_RAT", "id": "M0R715-1", "name": "lysophospholipase", "aln": "---------MGTPSHELNTTSSGSEVIRK-------ALEEGLGRRICVAQPVPFVPQVLGVMIGAGVAVLVTAVLILL---VVRRLRVQKTPAPEGPRYRFRKRDKVLFYGRKIMRKVSQSTSSLVDTSVSTTSRPRMKKKLKMLNIAKKILRIQKETPTLQRK--EPPPS------------VLEADLTEGDLANSHLPSEVLYMLKNVRVLGHFEKPLFLELCRHMVFQRLGQGDYVFRPGQPDASIYVVQDGLLELCLPGPD------------------------------------------------------------GKECVVKEVVPGDSVNSLLSILDVITGHQHPQR--------------------------------------------------TVSARAARDSTVLRLPVEAFSAVFTKYPESLVRVVQIIMVRLQRVTFLALHNYLGLTNELFSHEIQPLRLFPSPG---------------------LPTRTSPVRGSKRVVSTSGTEDTPKETSGRPLDPTGAPLPGPAGDPVKPTSLEAPSAP--------------------LLSRCISMPVDISGLQGGPRSDFDMAYERGRISVSLQEEASGGPQTASPRTPTQELREQPAGACEYSFCEDESATGGCPFGPYQGRQ-----------------------TSSIFEAAKRELAKLMRIE--DPSLLNS----------------------------------------------------------------------------------------------------RVLLHHAKAGTIIARQG-DQDVSLHFVLWGCLHVYQRMIDKA-----------------------EEVCLFVAQPGELVGQLAVLTGEPLIFTLRAQRDCTFLRISKSDFYEIMRAQPSVVLSAAHTVAARMSPFVRQMDFAIDWTAVEAGRALYRQGDRSDCTYIVLNGRLRSVIQRGSG-----------KKELVGEYGRGDLIGVVEALTRQPRATTVHAVRDTELAKLPEGTLGHIKRRYPQVVTRLIHLLSQKILGN-----------------LQQLQGPFPAGSGLSVPQHS---ELTNPASNLSTVAILPVCAEVPMMAFTLELQHALQAIG-PTLLLNSDIIRARLGASALDSIQEFRLSGWLAQQEDAHRIVLYQTDTSLTP-WTVRCLRQADCILIVGLG-DQEPTVGQLEQMLENTAVRALKQLVLLHREEG-PGPTRTVEWLNMRSWCSGHLHLRCPRR---------------------------LFSRRSPAKLHELYEKVFSRRAD-------------------RHSDFSRLARVLTGNTIALVLGGGGARGCSHIGVLKALEEAGVPVDLVGGTSIGSFIGALYAEERSASRTKQRAREWAKSMTSVLEPVLDLTYPVTSMFTGSAFNRSIHRVFQDKQIEDLWLPYFNVTTDITASAMRVHKDGSLWRYVRASMTLSGYLPPLCDPKDGHLLMDGGYINNLPADIARSMGAKTVIAIDVGSQDETDLSTYGDSLSGWWLLWKRLNPWADKVKVPDMAEIQSRLAYVSCVRQLEVVKSSSYCEYLRPSIDCFKTMDFGKFDQIYDVGYQYGKAVFGGWTRGEVIEKMLTDRRSTDLNESRRADILAFPSSGFTDLAEIVSRI-EPPTSYVSDGCADGEESD---------------------------CLTEYEEDAGPDCSRDEGGSPE--GASPSTA-SEVE---------------------------EEKSTLRQRRFLPQETGAQ----------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8IY17-4", "uniprot_id": "PLPL6_HUMAN", "id": "Q8IY17-4", "name": "Patatin-like phospholipase domain-containing protein 6", "aln": "MEAPLQTGMMGTSSHGLATNSSGAKVAERDGFQDVLAPGEGSAGRICGAQPVPFVPQVLGVMIGAGVAVVVTAVLILL---VVRRLRVPKTPAPDGPRYRFRKRDKVLFYGRKIMRKVSQSTSSLVDTSVSATSRPRMRKKLKMLNIAKKILRIQKETPTLQRK--EPPPA------------VLEADLTEGDLANSHLPSEVLYMLKNVRVLGHFEKPLFLELCRHMVFQRLGQGDYVFRPGQPDASIYVVQDGLLELCLPGPD------------------------------------------------------------GKECVVKEVVPGDSVNSLLSILDVITGHQHPQR--------------------------------------------------TVSARAARDSTVLRLPVEAFSAVFTKYPESLVRVVQIIMVRLQRVTFLALHNYLGLTNELFSHEIQPLRLFPSPG---------------------LPTRTSPVRGSKRMVSTSATDE-PRETPGRPPDPTGAPLPGPTGDPVKPTSLETPSAP--------------------LLSRCVSMPGDISGLQGGPRSDFDMAYERGRISVSLQEEASGGSLAAPARTPTQEPREQPAGACEYSYCEDESATGGCPFGPYQGRQ-----------------------TSSIFEAAKQELAKLMRIE--DPSLLNS----------------------------------------------------------------------------------------------------RVLLHHAKAGTIIARQG-DQDVSLHFVLWGCLHVYQRMIDKA-----------------------EDVCLFVAQPGELVGQLAVLTGEPLIFTLRAQRDCTFLRISKSDFYEIMRAQPSVVLSAAHTVAARMSPFVRQMDFAIDWTAVEAGRALYRQGDRSDCTYIVLNGRLRSVIQRGSG-----------KKELVGEYGRGDLIGVVEALTRQPRATTVHAVRDTELAKLPEGTLGHIKRRYPQVVTRLIHLLSQKILGN-----------------LQQLQGPFPAGSGLGVPPHS---ELTNPASNLATVAILPVCAEVPMVAFTLELQHALQAIG-PTLLLNSDIIRARLGASALDSIQEFRLSGWLAQQEDAHRIVLYQTDASLTP-WTVRCLRQADCILIVGLG-DQEPTLGQLEQMLENTAVRALKQLVLLHREEG-AGPTRTVEWLNMRSWCSGHLHLRCPRR---------------------------LFSRRSPAKLHELYEKVFSRRAD-------------------RHSDFSRLARVLTGNTIALVLGGGGARGCSHIGVLKALEEAGVPVDLVGGTSIGSFIGALYAEERSASRTKQRAREWAKSMTSVLEPVLDLTYPVTSMFTGSAFNRSIHRVFQDKQIEDLWLPYFNVTTDITASAMRVHKDGSLWRYVRASMTLSGYLPPLCDPKDGHLLMDGGYINNLPADIARSMGAKTVIAIDVGSQDETDLSTYGDSLSGWWLLWKRLNPWADKVKVPDMAEIQSRLAYVSCVRQLEVVKSSSYCEYLRPPIDCFKTMDFGKFDQIYDVGYQYGKAVFGGWSRGNVIEKMLTDRRSTDLNESRRADVLAFPSSGFTDLAEIVSRI-EPPTSYVSDGCADGEESD---------------------------CLTEYEEDAGPDCSRDEGGSPE--GASPSTA-SEME---------------------------EEKSILRQRRCLPQEPPGSATDA------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M2B6R2-1", "uniprot_id": "A0A8M2B6R2_DANRE", "id": "A0A8M2B6R2-1", "name": "lysophospholipase", "aln": "----------------MGQSTSDTESAEP-------PETDRFGNIKSLVEDQLQTSMVVGIVIGAGVVIVLIAVLIFF---VLRRMQLRKLEAQEVPKYRFRKRDKVLFYGRKIMRKVSQSTSSLVG--ATSSTRPRLKKKQKMLNIAKKILRFKKEVPTLQMK--EPPPS------------VLEADLTEFDVANSHLPSEVLYMLKNVRVLGHFEKPLFLELCKHMVFLQFQQGEYVFRPGQPDSSIYVVQDGKLELCLTGQD------------------------------------------------------------GKDGVVKEVYPGDSVHSLLSILDVITGHQRPYK--------------------------------------------------TVSARAAEVSTVLRLPVDAFLSIFEKYPESLVRVVQIIMVRLQRVTVLALHNYLGLTNELFSHEMQPRSSPLSP----------------------HPTRSSPVRHSKRFGSLTVPDKHREAAVQN----------ATGGDHGK----EGGTIP--------------------TLSRTISMPVDIAGMQKSLRSDFDMAYERGRISVSAEDGVP--AFTKEQRERKVTVDEVPSG--VYLYPEEESGMD--IFSSFQGRP-----------------------NATVFEEAQKEILRLMKIE--DPSLLNG----------------------------------------------------------------------------------------------------RVTFHHAKAGSVLARQG-DQDVSLHFVLSGCLHVYQKMIDKQ-----------------------EAVCLFVTQPGEMVGQLAVLTGEPLIFTIKAERDCTFLKISKSEFYEIMREQPSVVLSAAHTVAIRMSAFVRQMDFAIDWMAVEAGRALYRQDDQSDCTYIVLNGRLRSVIRKANG-----------KKELVGEYGRGDLIGVVEALTRQPRATTVHAVRDTELVKLPEGTLNNIKRRYPQVVTRLIHLLGQKILGN-----------------LQQPRGPFS-SSALGLPSMASSPDVTNPASNLSTVAVLPVCDEVPINAFNLELSHALSAIG-PTLLLTSDIIRERLGASALDSIHEYRLSGWLAQQEDINRIVLYQTDSGMTP-WTQRCIRQADCILIVGLG-DQEPALGELEQMLENTAVRALKQLILLHREDG-PGPSRTVEWLNMRSWCSGHLHLKCPRR---------------------------VFSRRSPTKLREVYEKVFEKTAD-------------------RHSDFSRLARVLTGNSIALVLGGGGARGCSHVGVIKAMEDTGIPIDIVGGTSIGSFIGALYAEERSAVRVKQRAREWSKAMNSVFKTVLDLTYPITSMFSGSAFNTSISKVFEDKQIEDLWLPYFNVTTDITASAMRVHKDGSLWRYVRASMTLSGYLPPLCDPKDGNLLMDGGYINNLPADIARTLGTKTVIAIDVGSQDETDLCNYGDCLSGWWLLWKRINPWAEKVKVPDMAEIQSRLAYVSCVRQLELVKKSAYCEYIRPPIDRFKTMDFGKFDEIYDVGYQHGKLVFTEWARGDIIDNMLKDHRSADYNDSKKTDSCPCPSADFTDLAEIVSRI-EPVQSYVG---ADAEESD---------------------------YATEYEEDGMDTVREEEGEEEEEEGEDPEDQ-SPGEWGPNGVFPP------------------DEDKTVRQRKNVSRDPNADFSGVSDC---------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9U969-1", "uniprot_id": "SWS_DROME", "id": "Q9U969-1", "name": "Neuropathy target esterase sws", "aln": "---------MDVLEMLRASASGSYNTIFS------DAWCQYVSKQITATVYMYFALVMMSLLFIAWFLYFKRMARLRLRDEIARSISTVTNSSGDMRGLRFRKRDKMLFYGRRMLRKMKNVSG-------QMYSSGKGYKRRAVMRFARRILQLRRDNMPLEMRTVEPPAE------------YLEETIEG----SDRVPPDALYMLQSIRIFGHFEKPVFLRLCKHTQLLELMAGDYLFKITDPDDSVYIVQSGMINVYISNAD------------------------------------------------------------GSTLSLKTVRKGESVTSLLSFIDVLSGNPSYYK--------------------------------------------------TVTAKAIEKSVVIRLPMQAFEEVFQDNPDVMIRVIQVIMIRLQRVLFTALRNYLGLNAELVQNHMRYKS---------------------------VSTMSGPINSQTSQSSRQAPNGPPMVISQMNLMQSAVSGTGSSGVSVT----VTRPPS--------------------SPSRHSREEHTLSDPNPNPDGSFHGTTN---LFTEVHGDAPNADLFHQQQQQHSVGNLSTRRSSITLMAPDGSHSCLQTPGVTTSID-----------------------MRLVQSSAVDSLRKELGLSEEDSHIIEP----------------------------------------------------------------------------------------------------FVELRELEPNVTLITEGNADDVCVWFVMTGTLAVYQSNQDATRAKQDK-----------------SDMLIHFVHPGEIVGGLAMLTGEASAYTIRSRSITRIAFIRRAAIYQIMRQRPRIVLDLGNGVVRRLSPLVRQCDYALDWIFLESGRAVYRQDESSDSTYIVLSGRMRSVITHPGG-----------KKEIVGEYGKGDLVGIVEMITETSRTTTVMAVRDSELAKLPEGLFNAIKLRYPIVVTKLISFLSHRFLGS-----------------MQTR-------SGSGAPGAP--VEANPVTHKYSTVALVPITDEVPMTPFTYELYHSLCAIG-PVLRLTSDVVRKQLGSNIFEAANEYRLTSWLAQQEDRNIITLYQCDSSLSA-WTQRCMRQADVILIVGLG-DRSHLVGKFEREIDRLAMRTQKELVLLYPEASNAKPANTLSWLNARPWVTKHHHVLCVKR---------------------------IFTRKSQYRINDLYSRVLLSEPN-------------------MHSDFSRLARWLTGNSIGLVLGGGGARGAAHIGMLKAIQEAGIPVDMVGGVSIGALMGALWCSERNITTVTQKAREWSKKMTKWFLQLLDLTYPITSMFSGREFNKTIHDTFGDVSIEDLWIPYFTLTTDITASCHRIHTNGSLWRYVRSSMSLSGYMPPLCDPKDGHLLLDGGYVNNLPADVMHNLGAAHIIAIDVGSQDDTDLTNYGDDLSGWWLLYKKWNPFTSPVKVPDLPDIQSRLAYVSCVRQLEEVKNSDYCEYIRPPIDKYKTLAFGSFDEIRDVGYVFGKNYFESMAKAGRLGRFN---QWFNKEPPKRVNHASLNEYTFIDLAQIVCRLPETYAVNTAELFSEDEDCDGYISEPTTLNTDRRRIQVSRAGNSLSFSETEMDSDVELDLKLERKTDKSTQSSPPSNSRSDMRGKEEARHMSNWHWGVKHKDETGSGATEATKTQTGQEQELQQEQQDQGATAEQLVDKDKEENKENRSSPNNETKN", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q04958-1", "uniprot_id": "NTE1_YEAST", "id": "Q04958-1", "name": "Lysophospholipase NTE1", "aln": "--MRSMNCTTNNTNNTGQNTKNSLGSSFNSSNYTSYRFQTCLTDQIISEAQTWSLSSLFNFSWVVSYFVMGASRMIFRYGWYLATLSLLRIPKWIFFKLHHVQFTLSFWLILFALAVIVFVTYTIMKERILSQYKRLTPEFLPLENTGKSGSSANINAASTQSAN-APPAIGSSTTGASSIIDSKKHSLKDGNENETFLSSYLDQFLSAIKIFGYLEKPVFHDLTKNMKTQKMDEGEILLLDSTIGFAIVVEGTLQLYHEVDHSDKDHGDETDHSDTDGLDDQDRDEEDEEEDDDIDNYDTKSCSSNLIDEEDESVGYIHLKNGLGNFQLLNTVKPGNPLTSLVSILNLFTHSMSSYGNSNFPSELSSPIDTTVSVNNMFCSSEQNFSNTDSMTNSTNSFPTFPSSMPKLVARAATDCTIGIIPPQSFAKLTAKYPRSASHIIQMVLTKLYHVTFQTAHDYLGLTKEIMDIEVLLNKSIVYELPYYLKEAVIRKFKTVDKSSGSADLEPKPKNSNASSKLKKPPKAKPSDGIIQSLKIANANANTSSNSLSLKPEFTHHPSSRHVVLGSRDQFNPGDLLSNVPLSRTMDILSPNPIHNNNRNKSNGINTSTSNQHKRSSRSSSNNASVHSKKFSSLSPELRNAQLSTSPLSLDNTSVHDHIHPSPVHLKGRVSPRPNLLPTTSFSAAQEETEDSALRMALVEAMLTYLGVNKSNMSVSSSSIANMSSLNSPQLNEMYSRRPSNASFLMSPHCTPSDISVASSFASPQTQPTMLRILPKEYTISNKRHNKSKSQDKKKPRAYKEELTPNLDFEDVKKDFAQGIQLKFFKKGTTIVEQN-ARGKGLFYIISGKVNVTTNSSSSVVSSMSKPEQVSAQSSHKGENPHHTQHLLYSVGSGGIVGYLSSLIGYKSFVNIVAKSDVYVGFLSSATLERLFDKYFLIYLRISDSLTKLLSSRLLKLDHALEWVHLRASETLFSQGDSANGIYVVLNGRLRQLQQQSLSNSNTSSEEVETQNIILGELAQGESFGEVEVLTAMNRYSTIVAVRDSELARIPRTLFELLALEHPSIMIRVSRLVAKKIVGDRTVPALTGDPLSIKENDFTSLIPPTKASYSSSLSHKP--QNITSGTITFRTITILPITSGLPVEAFAMKLVQAFKQVGRTTIGLNQRTTLTHLGRHAFDRLSKLKQSGYFAELEEMYQTVVYISDTPVKSNWTRTCIAQGDCILLLADARSPSAEIGEYEKLLLNSKTTARTELILLHPERY-VEPGLTHKWLRYRPWVHSHHHIQFSLTGTTLMNEGKMHVLNNGALALMDKLIQTEFSRKTQQNISKLLPDSIKNTVENFSSRFMKSKRQYYTPVHRHKNDFLRLARILSGQAIGLVLGGGGARGISHLGVIQAIEEQGIPVDVIGGTSIGSFVGGLYAKDYDLVPIYGRVKKFAGRISSIWRMLTDLTWPVTSYTTGHEFNRGIWKTFGDTRIEDFWIQYYCNSTNITDSVQEIHSFGYAWRYIRASMSLAGLLPPLEE--NGSMLLDGGYVDNLPVTEMRARGCQTIFAVDVGSADDRTPMEYGDSLNGFWIIFNRWNPFSSHPNIPNMAEIQVRLGYVASVNALEKAKNTPGVVYVRPPIEEYATLDFSKFEEIYHVGVDYGRIFLQGLIDDDKMPYIP--------GSQETTLNSQVPEFLLHRRNSI----------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ... :... . . : : :. : :: : : : : : . .: . : . : **. : : . :.. :*. ::::*::***:* * :: .: *: :: . :: : : : * *. :: * *:.: **:*:::::: .: *:* ..: :* ::* : . * :::*::: :* :* . : ::****. *:.. .: . * . . .. . . . . ** . : . . . . : : : : : : :. : : . : :: : . : :. . : ::: * : * . :. . .* :** *: * * .: :. . : : : .:: : * .. :. :*. : : *.*::* :.:..::: *.: :: *:**.**:*.: : . :: ::** .:*: .* ** :* * :*: ****:**.::*. : : .:* :: :: ::.::::*. : . . . . : . : . *::::*: :*: .* :* ::: :* ..: *.. ** :: : : :.::*: *: .:* *: :.. ** *: *.* **::. . . . :*: *: : . : .:*:**: * * * .**. *.* * *: *:*:: .: .: : : :.** **** *:*::*.********** :*:*:::*::: *:*:*::**.***:::*.*:..: . :.:::: :.. : ***:*:** :* ** * .* * ***:*: *: :*:** * .:*. * ***:*:**:*:* :*** : :* :*:****::***. : * ::*:**** *: *** *.*:*::::: **::. ::*::.:** **.**:.*. ** .*.: *:**.*: : *: *..*::* .** .*: : : : . . . : .* ", "identical_positions": 220, "similar_positions": 404, "identity": "11.85%" }, { "cls_id": "homologset.agr.MGI:1354724", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D4A1D3-1", "uniprot_id": "D4A1D3_RAT", "id": "D4A1D3-1", "name": "Sacsin", "aln": "MGTEETRWVR-VTVLRGCVGCRTVAVRATATGRDLKERIFAETGFPVAEQRLWRGDREIPDWIKIGDLT-SKTC-LFVNLQSKGLKGGGRFGQTTPPLVDFLKDILRRYPEGGQILKELIQNAEDAGATEVKFLYDETQYGTETLWSKDMAQYQGSALYVYNNAVFTPEDWHGIQEIARSRKKDDPLKVGRFGIGFNSVYHITDVPCIFSGDQIGMLDPHQTLFGPHESGQCWNLKDDIKEINELPDQFAPFIGVFGSTKETFTNGSFPGTFFRFPLRLQPSQLSSNLYTKQKVLELFDSFRADADTVLLFLKSVQAVSLHVREADGTEKLVFRVTASENKTLKHERPNSIKILGTAISNYCKKIPSNSVTCVTYHINIALEDESTKDAQKTSWLVCNSVGGRGISSKLDSLADELKFVPIIGLAMSLSGRD-EENGATSDFSGKAFCFLPLPPGEESRTGLPVHISGFFGLTDNRRSIKWRELDQWRDPAALWNQFLIVNVVPKAYATLILDSIKRLETEKSSDFPLSVDAIYKLWPEASKVKAHWHPVLGPLFSELFQHAVIYSVGGEWVKLEQVHFSELDESLESTQSVLNYLQRSGKQIARVPGNLAAAVQLSAASATSTASPVRKVTPVWVRQVLRKCAHLGSAEEKLHLLEFVLSDQAYSELLGLELLPLQSGAFVPFSSSVSDQDVVYITSEEFPRSLFPGLEARLILENLKPHLLAALKEAAQTRAQQLLWGYSGRPCTQLQLLNPERFARLIKEVMNTFWPGRELVVQWYPLSEDKHHPSISWLKMVWKNLYIHFSEDLTLFDEMPLIPRTPLDADQTCVELIRLRVPSVVILDDETEAQLPEFLADIVQKLGGIVLKRLDTSLQHPLVKKYIHSPLPSAILQIMEKIPLQKLCNQIASLLPTHKDALRKFLASLTDTSEKEKRIIQELTIFKRINHSSDQGISSYTKLKGCKVLDHTAKLPTELRLSVSVIDSSDEATIRLANMLKIEKLKTTSCLKFVLKDIENAFYTQEEVTRLMLWILENLSSLKNENPSVLDWLMPLKFIHMSQEHVVAASDLFDPDIEVLRDLFYNEEEACFPP-AVFTSPDILHSLRQIGLKNEASLKEKDVVQVAKKIEALQVSSCQNQDVLLKKAKTLLLVLNKNHTLLQSSEGKMALKKIKWVPACKERPPNYPGSLVWKGDLCNLCAPPDMCDAAHAVLVGSSLPLVESAHVSLEKTLGIFTKPTISAVLKHFKIVVDWYTSKTFSDEDYYQFQHILLEIYGFMHDHLSEGKDSFKALKYPWVWTGKNFCPLAQAVIKPIHDLDLQPYLYNVPKTMAKFHQLFKACGSIEELTSDHISMVIQKVYLKSDQELSEEESKQNLHLMLNIMRWLYSNQIPASPNTPVPIYHSKNPSKLVMKPIHECCYCDIKVDDLNDLLEDSVEPIILVHEDIPMKTAEWLKVPCLSTRLINPENMGFEQSGQREPLTVRIKNILEEYPSVSDIFKELLQNADDANATECSFMIDMRRNMDIRENLLDPGMAACHGPALWSFNNSEFSDSDFINITRLGESLKRGEVDKVGKFGLGFNSVYHITDIPIIMSREFMIMFDPNINHISKHIKDRSNPGIKINWSKQQKRLRKFPNQFKPFIDVFGCQLPLAVEAPYSYNGTLFRLSFRTQQEAKVSEVSSTCYNTADIYSLVDEFSLCGHRLIIFTQSVNSMYLKYLKIEETNPTLAQDTIIIKKKACPSKALNAPVLSVLKEAAKLMKTCSSSNKKLPTDVPKSSCILQITVEEFHHVFRRIADLQSPLFRGPDDDPATLFEMAKSG-QSKKPSDELPQKTVDCTTWLICTCMDTGEALKFSLNESGRRLGLVPCGAVGVLLHETQEQKWTVKP---HIGEVFCYLPLRIKTGLPIHINGCFAVTSNRKEIWKTDTKGRWNTTFMRHVIVKAYLQALSVLRDLAISGELIDYTYYAVWPDPDVVHDDFSVICQGFYEDIAHGKGKDLTRVFSDGSMWVSMKNVRFLDDSILQRKDVGSAAFKIFLKYLKKTGSKNLCAVELPSSVKVGFEEAGCKQILLENTFSEKQFFSEVFFPNIQEIEAELRDPLMNFVLNEKLDEFSGILRVTPCVPCSLEGHPLVLPSRLIHPEGRVAKLFDIKDGRFPYGSTQDYLNPIILIKLVQLGMAKDDILWDDMLERAESVAEINKSDHAAACLRSSILLSLIDEKLKIRDPRAKDFAAKYQTIPFLPFLTKPAGFSLEWKGNSFKPETMFAATDLYTAEYQDIVCLLQPILNENSHSFRGCGSVSLAVKEFLGLLKKPTVDLVINQLKQVAKSVDDGITLYQENITNACYKYLHEAILQNEMAKATIIEKLKPFCFILVENVYVESEKVSFHLNFEAAPYLYQLPNKYKNNFRELFESVGVRQSFTVEDFALVLESIDQERGKKQITEENFQLCRRIISEGIWSLIREKRQEFCEKNYGKILLPDTNLLLLPAKSLCYNDCPWIKVKDSSVKYCHADIPREVAVKLGAIPKRHKALERYASNICFTAPGTEFGQKEKLTSRIKSILNAYPSEKEMLKELLQNADDAKATEICFVFDPRQHPVDRIFDDKWAPLQGPALCVYNNQPFTEDDVRGIQNLGKGTKEGNPCKTGQYGIGFNSVYHITDCPSFISGNDILCIFDPHARYAPGATSVSPGRMFRDLDADFRTQFSDVLDLYLGNHFKLDNCTMFRFPLRNAEMAQVSEISSVPSSDRMVQNLLDKLRSDGAELLMFLNHMEKISICEIDKATGGLNVLYSVKGKITDGDRLKRKQFHASVIDSVTKKRQLKDIPVQQITYTMDTEDSEGNLTTWLICNRSGFSSMDKVSKSVISAHRNQDITLFPRGGVAACITHNYKKPHRAFCFLPLSLETGLPFHVNGHFALDSARRNLWRDDNGVGVRSDWNNSLMTALIAPAYVELLIQLKKRYFPGSDPTLSVLQNTPIHVVKDTLKKFLSFFPVNRLDLQPDLYCLVKALYSCIHEDMKRLLPVVRAPNIDGSDLHSAVIITWINMSTSNKTKPFFDNLLQDELQHLKNADYNITTRKTVAENVYRLKHLLLEIGFNLVYNCDETANLYHCLVDAAIPVSYVTPADVRSFLMTFSSPDTNCHIGKLPCRLQQTNLKLFHSLKLLVDYCFKDAEESEFEVEGLPLLITLDSVLQIFDGKRPKFLTTYHELIPSRKDLFMNTLYLKYSSVLLNCKVAKVFDISSFADLLSSVLPREYKTKNCAKWKDNFASESWLKNAWHFISESVSVTDDQEEPKPAFDVIVDILKDWALLPGTKFTVSASQLVVPEGDVLIPLSLMHIAVFPNAQSDKVFHALMKAGCIQLALNKICSKDSALVPLLSCHTANIDSPASILKAVHYMVQTSTFRTEKLVENDFEALLMYFNCNLSHLMSQDDLKILKSLPCYKSISGRYMSIAKFGTCYVLTKSIPSAEVEKWTQSSSSAFLEEKVHLKELYEVLGCVPVDDLEVYLKHLLPKIENLSYDAKLEHLIYLKNRLASIEELSETKEQLFEKLESLLIIHDANNRLKQAKHFYDRTVRVFEVMLPEKLFIPKEFFKKLEQVIKPKNQVVFMTSWVEFLRNIGLKHVLSQQQLLQFAKEISVRANTENWSKETLQNTVDILLHHIFQERTDLLSGNFLKELSLIPFLCPERAPAEYIRFHPQYQEVNGTLPLIKFNGAQVNPKFKQCDVLQLLWTSCPILPEKATPLSIKEQEGSSLAPQEQLEQVLNMLNVNLDPPLDKVINNCRNICNITTLDEEMVKTRAKVLRSIYEFLSAEKREFRFQLRGVAFVMVEDGWKLLKPEEVVINLEYEADFKPYLYKLPLELGTFHQLFKHLGTEDIISTKQYVEVLSRIFKNSEGKQLDPNEMRTVKRVVSGLFKSLQNDSVKVRSDLENARDLALYLPSQDGRLVKSSILVFDDAPHYKSRIQGNIGVQMLVDLSQCYLGKDHGFHTKLIMLFPQKLRPRLLSSILEEQLDEETPKVCQFGALCSLQGRLQLLLSSEQFITGLIRIMKHENDNAFLANEEKAIRLCKALREGLKVSCFEKLQTTLRVKGFNPIPHSRSETFAFLKRFGNAVILLYIQHSDSKDINFLLALAMTLKSATDNLISDTSYLIAMLGCNDIYRISEKLDSLGVKYDSSEPSKLELPMPGTPIPAEIHYTLLMDPMNVFYPGEYVGYLVDAEGGDIYGSYQPTYTYAIIVQEVEREDADNASFLGKIYQIDIGYSEYKIVSSLDLYKFSRPDESSQSRDSAPTTPTSPTEFLTPGLRSIPPLFSGKESHKPASSKHHSPRKLKVNALPEILKEVTSVVEQAWKLPESERKKIIRRLYLKWHPDKNPENHDIANEVFKHLQNEINRLEKQAFLDQNADRASRRTFSTSASRFQSDKYSFQRFYTSWNQEATSHKSERQQQSKEKCPPSAGQTYSQRFFVPPTFKSVGNPVEARRWLRQARANFSAARNDLHKNANEWVCFKCYLSTKLALIAADYAVRGKSDKDVKPTALAQKIEEYSQQLEGLTNDVHTLEAYGVDSLKTRYPDLLPFPQIPNDRFTSEVAMRVMECTACIIIKLENFIQQKV", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9JLC8-1", "uniprot_id": "SACS_MOUSE", "id": "Q9JLC8-1", "name": "Sacsin", "aln": "METKFQRWVR-VTVLRGCVGCRTVAVPATATGRDLKERIFAETSFPVAEQRLWRGDREVPDWIKIGDLT-SKTCHLFVNLQSKGLKGGGRFGQTTPPLVDFLKDILRRYPEGGQILKELIQNAEDAGATEVKFLYDETQYGTETLWSKDMAQYQGSALYVYNNAVFTPEDWHGIQEIARSRKKDDPLKVGRFGIGFNSVYHITDVPCIFSGDQIGMLDPHQTLFGPHESGQCWNLKDDIKEINELPDQFAPFIGVFGSTKETFTNGSFPGTFFRFPLRLQPSQLSSNLYTKQKVLELFDSFRADADTVLLFLKSVQAVSLHVREADGTEKLVFRVTASENKALKHERPNSIKILGTAISNYCKKIPSNSVTCVTYHINIVLEDESTKDAQKTSWLVCNSVGGRGISSKLDSLADELKFVPIIGLAMPLSGKD-EENGAISDFSGKAFCFLPLPPGEESRTGLPVHISGFFGLTDNRRSIKWRELDQWRDPAALWNEYLIVNVVPKTYATLILDSIKRLETEKSSDFPLSVDTIYKLWPEASKVKAHWHPVLGPLFSELFQHAVIYSIGGEWVKLEQVHFSELDGSLESTRSVLNYLQSSGKQIAKVPGNLAAAVQLSAASATSSASPVRKVTPAWVRQVLRKCAHLGSAEEKLHLLEFVLSDQAYSELLGLELLPLQSGAFVPFSSSVSDQDVVYITSEEFPRSLFPGLEARLILENLKPHLLAALKEAAQTR---------GRPCTQLQLLNPERFARLIKEVMNTFWPGRELVVQWYPFSEDKRHPSLSWLKMVWKNLYIHFSEDLTLFDEMPLIPRTLLNEDQTCVELIRLRIPSVVILDDETEAQLPEFLADIVQKLGGIVLKRLDTSIQHPLVKKYIHSPLPSAILQIMEKIPLQKLCNQIASLLPTHKDALRKFLASLTDTSEKEKRIIQELTIFKRINHSSDQGISSYTKLKGCKVLDHTAKLPTDLRLSVSVIDSSDEATIRLANMLKIEKLKTTSCLKFVLKDIGNAFYTQEEVTQLMLWILENLSSLKNENSNVLDWLMPLKFIHMSQGHVVAAGDLFDPDIEVLRDLFYNEEEACFPP-TIFTSPDILHSLRQIGLKNESSLKEKDVVQVARKIEALQVSSCQNQDVLMKKAKTLLLVLNKNQTLLQSSEGKMALKKIKWVPACKERPPNYPGSLVWKGDLCNLCAPPDMCDAAHAVLVGSSLPLVESVHVNLEQALSIFTKPTINAVLKHFKTVVDWYTSKTFSDEDYYQFQHILLEIYGFMHDHLSEGKDSFKALKFPWVWTGKNFCPLAQAVIKPTHDLDLQPYLYNVPKTMAKFHQLFKACGSIEELTSDHISMVIQKVYLKSDQELSEEESKQNLHLMLNIMRWLYSNQIPASPNTPVPIYHSRNPSKLVMKPIHECCYCDIKVDDLNDLLEDSVEPIILVHEDIPMKTAEWLKVPCLSTRLINPENMGFEQSGQREPLTVRIKNILEEYPSVSDIFKELLQNADDANATECSFMIDMRRNMDIRENLLDPGMAACHGPALWSFNNSEFSDSDFLNITRLGESLKRGEVDKVGKFGLGFNSVYHITDIPIIMSREFMIMFDPNINHISKHIKDRSNPGIKINWSKQQKRLRKFPNQFKPFIDVFGCQLPLAVEAPYSYNGTLFRLSFRTQQEAKVSEVSSTCYNTADIYSLVDEFSLCGHRLIIFTQSVNSMYLKYLKIEETNPSLAQDTIIIKKKVCPSKALNAPVLSVLKEAAKLMKTCSSSNKKLPTDVPKSSCILQITVEEFHHVFRRIADLQSPLFRGPDDDPATLFEMAKSG-QSKKPSDELPQKTVDCTTWLICTCMDTGEALKFSLNESGRRLGLVPCGAVGVLLHETQEQKWTVKP---HIGEVFCYLPLRIKTGLPIHINGCFAVTSNRKEIWKTDTKGRWNTTFMRHVIVKAYLQALSVLRDLAIGGELTDYTYYAVWPDPDLVHDDFSVICKGFYEDIAHGKGKELTRVFSDGSMWVSMKNVRFLDDSILQRKDVGSAAFKIFLKYLKKTGSKNLCAVELPSSVKAGFEEAGCKQILLENTFSEKQFFSEVFFPNIQEIEAELRDPLMNFVLNEKLDEFSGILRVTPCVPCSLEGHPLVLPSRLIHPEGRVAKLFDTKDGRFPYGSTQDYLNPIILIKLVQLGMAKDDILWDDMLERAESVAEINKSDHAAACLRSSILLSLIDEKLKIKDPRAKDFAAKYQTIPFLPFLTKPAGFSLEWKGNSFKPETMFAATDIYTAEYQDIVCLLQPILNENSHSFRGCGSVSLAVKEFLGLLKKPTVDLVINQLKQVAKSVDDGITLYQENITNACYKYLHEAVLQNEMAKATIIEKLKPFCFILVENVYVESEKVSFHLNFEAAPYLYQLPNKYKNNFRELFESVGVRQSFTVEDFALVLESIDQERGKKQITEENFQLCRRIISEGIWSLIREKRQEFCEKNYGKILLPDTNLLLLPAKSLCYNDCPWIKVKDSTVKYCHADIPREVAVKLGAIPKRHKALERYASNICFTALGTEFGQKEKLTSRIKSILNAYPSEKEMLKELLQNADDAKATEICFVFDPRQHPVDRIFDDKWAPLQGPALCVYNNQPFTEDDVRGIQNLGKGTKEGNPCKTGHYGIGFNSVYHITDCPSFISGNDILGIFDPHARYAPGATSVSPGRMFRDLDADFRTQFSDVLDLYLGNHFKLDNCTMFRFPLRNAEMAQVSEISSVPSSDRMVQNLLDKLRSDGAELLMFLNHMEKISICEIDKATGGLNVLYSVKGKITDGDRLKRKQFHASVIDSVTKKRQLKDIPVQQITYTMDTEDSEGNLTTWLICNRSGFSSMEKVSKSVISAHKNQDITLFPRGGVAACITHNYKKPHRAFCFLPLSLETGLPFHVNGHFALDSARRNLWRDDNGVGVRSDWNNSLMTALIAPAYVELLIQLKKRYFPGSDPTLSVLQNTPIHVVKDTLKKFLSFFPVNRLDLQPDLYCLVKALYSCIHEDMKRLLPVVRAPNIDGSDLHSAVIITWINMSTSNKTRPFFDNLLQDELQHLKNADYNITTRKTVAENVYRLKHLLLEIGFNLVYNCDETANLYHCLVDADIPVSYVTPADVRSFLMTFSSPDTNCHIGKLPCRLQQTNLKLFHSLKLLVDYCFKDAEESEFEVEGLPLLITLDSVLQIFDGKRPKFLTTYHELIPSRKDLFMNTLYLKYSSVLLNCKVAKVFDISSFADLLSSVLPREYKTKNCAKWKDNFASESWLKNAWHFISESVSVTDDQEEPKPAFDVIVDILKDWALLPGTKFTVSTSQLVVPEGDVLIPLSLMHIAVFPNAQSDKVFHALMKAGCIQLALNKICSKDSALVPLLSCHTANIDSPASILKAVHYMVQTSTFRTEKLMENDFEALLMYFNCNLSHLMSQDDIKILKSLPCYKSISGRYMSIAKFGTCYVLTKSIPSAEVEKWTQSSSSAFLEEKVHLKELYEVLGCVPVDDLEVYLKHLLPKIENLSYDAKLEHLIYLKNRLASIEEPSEIKEQLFEKLESLLIIHDANNRLKQAKHFYDRTVRVFEVMLPEKLFIPKEFFKKLEQVIKPKNQAAFMTSWVEFLRNIGLKYALSQQQLLQFAKEISVRANTENWSKETLQSTVDILLHHIFQERMDLLSGNFLKELSLIPFLCPERAPAEYIRFHPQYQEVNGTLPLIKFNGAQVNPKFKQCDVLQLLWTSCPILPEKATPLSIKEQEGSDLAPQEQLEQVLNMLNVNLDPPLDKVINNCRNICNITTLDEEMVKTRAKVLRSIYEFLSAEKREFRFQLRGVAFVMVEDGWKLLKPEEVVINLEYEADFKPYLYKLPLELGTFHQLFKHLGTEDIISTKQYVEVLSRIFKSSEGKQLDPNEMRTVKRVVSGLFKSLQNDSVKVRSDLENARDLALYLPSQDGKLVKSSILVFDDAPHYKSRIQGNIGVQMLVDLSQCYLGKDHGFHTKLIMLFPQKLRPRLLSSILEEQLDEETPKVCQFGALCSLQGRLQLLLSSEQFITGLIRIMKHENDNAFLANEEKAIRLCKALREGLKVSCFEKLQTTLRVKGFNPIPHSRSETFAFLKRFGNAVILLYIQHSDSKDINFLLALAMTLKSATDNLISDTSYLIAMLGCNDIYRISEKLDSLGVKYDSSEPSKLELPMPGTPIPAEIHYTLLMDPMNVFYPGEYVGYLVDAEGGDIYGSYQPTYTYAIIVQEVEREDADNTSFLGKIYQIDIGYSEYKIVSSLDLYKFSRPDESSQNRDSAPTTPTSPTEFLTPGLRSIPPLFSGKESHKSPSTKHHSPRKLKVNALPEILKEVTSVVEQAWKLPESERKKIIRRLYLKWHPDKNPENHDIANEVFKHLQNEINRLEKQAFLDQNADRASRRTFSTSASRFQSDKYSFQRFYTSWNQEATSHKSERQQQSKEKCPPSAGQTYSQRFFVPPTFKSVGNPVEARRWLRQARANFSAARNDLHKNANEWVCFKCYLSTKLALIAADYAVRGKSDKDVKPTALAQKIEEYSQQLEGLTNDVHTLEAYGVDSLKTRYPDLLPFPQIPNDRFTSEVAMRVMECTACIIIKLENFIQQKV", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9NZJ4-1", "uniprot_id": "SACS_HUMAN", "id": "Q9NZJ4-1", "name": "Sacsin", "aln": "METKENRWVP-VTVLPGCVGCRTVAALASWTVRDVKERIFAETGFPVSEQRLWRGGRELSDWIKIGDLT-SKNCHLFVNLQSKGLKGGGRFGQTTPPLVDFLKDILRRYPEGGQILKELIQNAEDAGATEVKFLYDETQYGTETLWSKDMAPYQGPALYVYNNAVFTPEDWHGIQEIARSRKKDDPLKVGRFGIGFNSVYHITDVPCIFSGDQIGMLDPHQTLFGPHESGQCWNLKDDSKEISELSDQFAPFVGIFGSTKETFINGNFPGTFFRFPLRLQPSQLSSNLYNKQKVLELFESFRADADTVLLFLKSVQDVSLYVREADGTEKLVFRVTSSESKALKHERPNSIKILGTAISNYCKKTPSNNITCVTYHVNIVLEEESTKDAQKTSWLVCNSVGGRGISSKLDSLADELKFVPIIGIAMPLSSRDDEAKGATSDFSGKAFCFLPLPPGEESSTGLPVHISGFFGLTDNRRSIKWRELDQWRDPAALWNEFLVMNVVPKAYATLILDSIKRLEMEKSSDFPLSVDVIYKLWPEASKVKVHWQPVLEPLFSELLQNAVIYSISCDWVRLEQVYFSELDENLEYTKTVLNYLQSSGKQIAKVPGNVDAAVQLTAASGT---TPVRKVTPAWVRQVLRKCAHLGCAEEKLHLLEFVLSDQAYSELLGLELLPLQNGNFVPFSSSVSDQDVIYITSAEYPRSLFPSLEGRFILDNLKPHLVAALKEAAQTR---------GRPCTQLQLLNPERFARLIKEVMNTFWPGRELIVQWYPFDENRNHPSVSWLKMVWKNLYIHFSEDLTLFDEMPLIPRTILEEGQTCVELIRLRIPSLVILDDESEAQLPEFLADIVQKLGGFVLKKLDASIQHPLIKKYIHSPLPSAVLQIMEKMPLQKLCNQITSLLPTHKDALRKFLASLTDSSEKEKRIIQELAIFKRINHSSDQGISSYTKLKGCKVLHHTAKLPADLRLSISVIDSSDEATIRLANMLKIEQLKTTSCLKLVLKDIENAFYSHEEVTQLMLWVLENLSSLKNENPNVLEWLTPLKFIQISQEQMVSAGELFDPDIEVLKDLFCNEEGTYFPP-SVFTSPDILHSLRQIGLKNEASLKEKDVVQVAKKIEALQVGACPDQDVLLKKAKTLLLVLNKNHTLLQSSEGKMTLKKIKWVPACKERPPNYPGSLVWKGDLCNLCAPPDMCDVGHAILIGSSLPLVESIHVNLEKALGIFTKPSLSAVLKHFKIVVDWYSSKTFSDEDYYQFQHILLEIYGFMHDHLNEGKDSFRALKFPWVWTGKKFCPLAQAVIKPIHDLDLQPYLHNVPKTMAKFHQLFKVCGSIEELTSDHISMVIQKIYLKSDQDLSEQESKQNLHLMLNIIRWLYSNQIPASPNTPVPIHHSKNPSKLIMKPIHECCYCDIKVDDLNDLLEDSVEPIILVHEDIPMKTAEWLKVPCLSTRLINPENMGFEQSGQREPLTVRIKNILEEYPSVSDIFKELLQNADDANATECSFLIDMRRNMDIRENLLDPGMAACHGPALWSFNNSQFSDSDFVNITRLGESLKRGEVDKVGKFGLGFNSVYHITDIPIIMSREFMIMFDPNINHISKHIKDKSNPGIKINWSKQQKRLRKFPNQFKPFIDVFGCQLPLTVEAPYSYNGTLFRLSFRTQQEAKVSEVSSTCYNTADIYSLVDEFSLCGHRLIIFTQSVKSMYLKYLKIEETNPSLAQDTVIIKKKSCSSKALNTPVLSVLKEAAKLMKTCSSSNKKLPSDEPKSSCILQITVEEFHHVFRRIADLQSPLFRGPDDDPAALFEMAKSG-QSKKPSDELSQKTVECTTWLLCTCMDTGEALKFSLSESGRRLGLVPCGAVGVQLSEIQDQKWTVKP---HIGEVFCYLPLRIKTGLPVHINGCFAVTSNRKEIWKTDTKGRWNTTFMRHVIVKAYLQVLSVLRDLATSGELMDYTYYAVWPDPDLVHDDFSVICQGFYEDIAHGKGKELTKVFSDGSTWVSMKNVRFLDDSILKRRDVGSAAFKIFLKYLKKTGSKNLCAVELPSSVKLGFEEAGCKQILLENTFSEKQFFSEVFFPNIQEIEAELRDPLMIFVLNEKVDEFSGVLRVTPCIPCSLEGHPLVLPSRLIHPEGRVAKLFDIKDGRFPYGSTQDYLNPIILIKLVQLGMAKDDILWDDMLERAVSVAEINKSDHVAACLRSSILLSLIDEKLKIRDPRAKDFAAKYQTIRFLPFLTKPAGFSLDWKGNSFKPETMFAATDLYTAEHQDIVCLLQPILNENSHSFRGCGSVSLAVKEFLGLLKKPTVDLVINQLKEVAKSVDDGITLYQENITNACYKYLHEALMQNEITKMSIIDKLKPFSFILVENAYVDSEKVSFHLNFEAAPYLYQLPNKYKNNFRELFETVGVRQSCTVEDFALVLESIDQERGTKQITEENFQLCRRIISEGIWSLIREKKQEFCEKNYGKILLPDTNLMLLPAKSLCYNDCPWIKVKDTTVKYCHADIPREVAVKLGAVPKRHKALERYASNVCFTTLGTEFGQKEKLTSRIKSILNAYPSEKEMLKELLQNADDAKATEICFVFDPRQHPVDRIFDDKWAPLQGPALCVYNNQPFTEDDVRGIQNLGKGTKEGNPYKTGQYGIGFNSVYHITDCPSFISGNDILCIFDPHARYAPGATSISPGRMFRDLDADFRTQFSDVLDLYLGTHFKLDNCTMFRFPLRNAEMAKVSEISSVPASDRMVQNLLDKLRSDGAELLMFLNHMEKISICEIDKSTGALNVLYSVKGKITDGDRLKRKQFHASVIDSVTKKRQLKDIPVQQITYTMDTEDSEGNLTTWLICNRSGFSSMEKVSKSVISAHKNQDITLFPRGGVAACITHNYKKPHRAFCFLPLSLETGLPFHVNGHFALDSARRNLWRDDNGVGVRSDWNNSLMTALIAPAYVELLIQLKKRYFPGSDPTLSVLQNTPIHVVKDTLKKFLSFFPVNRLDLQPDLYCLVKALYNCIHEDMKRLLPVVRAPNIDGSDLHSAVIITWINMSTSNKTRPFFDNLLQDELQHLKNADYNITTRKTVAENVYRLKHLLLEIGFNLVYNCDETANLYHCLIDADIPVSYVTPADIRSFLMTFSSPDTNCHIGKLPCRLQQTNLKLFHSLKLLVDYCFKDAEENEIEVEGLPLLITLDSVLQTFDAKRPKFLTTYHELIPSRKDLFMNTLYLKYSNILLNCKVAKVFDISSFADLLSSVLPREYKTKSCTKWKDNFASESWLKNAWHFISESVSVKEDQEETKPTFDIVVDTLKDWALLPGTKFTVSANQLVVPEGDVLLPLSLMHIAVFPNAQSDKVFHALMKAGCIQLALNKICSKDSAFVPLLSCHTANIESPTSILKALHYMVQTSTFRAEKLVENDFEALLMYFNCNLNHLMSQDDIKILKSLPCYKSISGRYVSIGKFGTCYVLTKSIPSAEVEKWTQSSSSAFLEEKIHLKELYEVIGCVPVDDLEVYLKHLLPKIENLSYDAKLEHLIYLKNRLSSAEELSEIKEQLFEKLESLLIIHDANSRLKQAKHFYDRTVRVFEVMLPEKLFIPNDFFKKLEQLIKPKNHVTFMTSWVEFLRNIGLKYILSQQQLLQFAKEISVRANTENWSKETLQNTVDILLHHIFQERMDLLSGNFLKELSLIPFLCPERAPAEFIRFHPQYQEVNGTLPLIKFNGAQVNPKFKQCDVLQLLWTSCPILPEKATPLSIKEQEGSDLGPQEQLEQVLNMLNVNLDPPLDKVINNCRNICNITTLDEEMVKTRAKVLRSIYEFLSAEKREFRFQLRGVAFVMVEDGWKLLKPEEVVINLEYESDFKPYLYKLPLELGTFHQLFKHLGTEDIISTKQYVEVLSRIFKNSEGKQLDPNEMRTVKRVVSGLFRSLQNDSVKVRSDLENVRDLALYLPSQDGRLVKSSILVFDDAPHYKSRIQGNIGVQMLVDLSQCYLGKDHGFHTKLIMLFPQKLRPRLLSSILEEQLDEETPKVCQFGALCSLQGRLQLLLSSEQFITGLIRIMKHENDNAFLANEEKAIRLCKALREGLKVSCFEKLQTTLRVKGFNPIPHSRSETFAFLKRFGNAVILLYIQHSDSKDINFLLALAMTLKSATDNLISDTSYLIAMLGCNDIYRIGEKLDSLGVKYDSSEPSKLELPMPGTPIPAEIHYTLLMDPMNVFYPGEYVGYLVDAEGGDIYGSYQPTYTYAIIVQEVEREDADNSSFLGKIYQIDIGYSEYKIVSSLDLYKFSRPEESSQSRDSAPSTPTSPTEFLTPGLRSIPPLFSGRESHKT-SSKHQSPKKLKVNSLPEILKEVTSVVEQAWKLPESERKKIIRRLYLKWHPDKNPENHDIANEVFKHLQNEINRLEKQAFLDQNADRASRRTFSTSASRFQSDKYSFQRFYTSWNQEATSHKSERQQQNKEKCPPSAGQTYSQRFFVPPTFKSVGNPVEARRWLRQARANFSAARNDLHKNANEWVCFKCYLSTKLALIAADYAVRGKSDKDVKPTALAQKIEEYSQQLEGLTNDVHTLEAYGVDSLKTRYPDLLPFPQIPNDRFTSEVAMRVMECTACIIIKLENFMQQKV", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M3APK9-1", "uniprot_id": "A0A8M3APK9_DANRE", "id": "A0A8M3APK9-1", "name": "", "aln": "MATGQDPWLPWVIVSHDCLGTRVFQVPSSTVIRSIKTLIYEETDYPVSEQQLFHNGKMVHDGVEIGNLVPHGDHEIIMTLHGRGPRGGGRFGQTTPPLVDFLKDILRRYPEGGQILKELIQNAEDAGATEVKFLYDETEYGVESLWSHDMAQYQGTALYVYNDAVFTTEDWNGIQEIARSRKREDPLKVGRFGIGFNSVYHITDVPSIFSGDQIAMLDPHQMLFGVHESGQCWNLKSDIKEITELSDQFSPYFGLLGSSEKTIKDGNFPGTLFRFPLRMKPSQLSNNIYNKEKVLELFESFKVDADTVLLFLKSVQKVSLHVRESDGTERMLFQVTASDSQEDRMERPNSLKTLGQAIDSYSNGVPGSSVTCATYQLSIEARDETAKETQKTTWLVCNSVGGRGMCGELDSLADDLKFIPTIGIALPLTLID-EDKGATSSFSGRAFCFLPLPLGEESMTGLPVHVSGFFGLTDNRRSIKWREVDQWRDPAALWNELLIVTVIPRAYFTLIMETIQRIQTKKDQDFPLSPRGIYGAWPDPNRIRPRWKPILEPLLNDLLQHPVIYSISGSWVQVDETVFSDLDSSMDTAGTIIKYLQTSGMMLAQVPAYIDEALTMFVTKPG----SLRRVTPSFVRQTLRKCRHKGPSTEKLLLLEFILSDSCYNDLIGLELLPLQDETFAVFSSSVNDKDAVYIASQEYPRSLYPGLEGRFVLESIPPHVMTSLKEAAKSRVQQYLWGCSGRPCTQVQVLTPERSARLIKEVLTTAWPSRDFAVQWNPGDQEKKHPSASWLRMIWKHLYINFADDLSVFEDLPLIPNVPLADTLDCLELLRLKSPSPIVLVNEEEGPPSEDLLEVMKKLGCVILKQIDPCLHHPLLKNYIHQSSPSTLLQIMDRSTSQRLASQVSSLTVKQRLALRSFLAGLTDVTEKEKRIIQELPIFDKVGQKSKTDTSPLTLLKGARVLHHTAKHPLDVKLSINVVDCSDEATIRLVKLLNIEQVKSTECLKVIIQDIEKGFYTKEEVTKIMLWALTYLSFLKNENKAVISWLSSLKFIHTASEKLHSPTDFFDPELEILQNLFFMEEKVRFPPDDFMSSPDVLHSLRQLGLKNEVQLNEKDVLQVARKIEELQGNSKPEWDPILKKAKTLLTILNKQTKLVKSSEVQTNLQKLKWVPVCKDRPLNYPKSLAWRGDSCNISSLSEMCDISYAVLVGSSVSLVERTSAGMKKALKLSLEPQVDQVLQHLKAVNDWHQSQAFTTEDWYQFQQILCEIYEFMQAHLEDAREALKSLSFDWVWTGKTFASPGCTVLKPIPDLDLQPYLYSLPKTIAKFNKLFKFCGSIEEVVPSHVFEVVKTIRQRCEEEMTKQESKRNVLLLINILRWLYSSQIPVDADMHVPILYHKDPSKLVMKPIHECTYCDIKVEDLNDLLDDASEPIILVHDDIPMKTAEWLKVPCLSTRLINPENLGFEQSGQREPLTVRIKNILEEYPSVADIFKELLQNADDANATECSFLIDMRKNLEIRENLLDPGMIICHGPALWSFNNSVFSDTDFLNITRLGGSMKRCEADKVGKFGLGFNSVYHVTDIPIIMSREFMIMFDPNINHIGKHIRDKSNPGIKINWSKQQKRLRKFPNQFRPFINVFNCQLPLSLEAPYKYDGTLFRLPFRTEQEASASEISGIYYNTTDIYSLVDEFSICGHRLILFTQHVGTMVLKYLKCEEPNPAAAQDVVTINKSVWSSKAAYGP-LSILKSAAKVMKKVAATS-KVPTEVPKSGCIIRIIVEEYHNVFRRIVDLQSPLFRGSDEDPSSYFEMAAKGTQTKRLTDDMPQKGVENTNWLICSCMDVTEALKFSLNDSGKRLGLVPCGGIAVLLTEEENRKWTVKTSATPIGEVFCYLPLRIKTGLPVHINGCFAVTSNRKEIWKTDTKGQWNSIFMRHVIVQAYLAALNMLRSMAESGELLDYSYYAAWPDPGVVHDDFNLICQGVYQEIAKGADDDRAKVFSDGKTWVSIKNVRFLDDSLLCRPDIGSAAFKIFLKYLRKCGSQDLCAVELPEWVKEGFDDAGCKGKLMENTLTEKQFFSDVFFPHIQDIDKDLRDPLMYYVLNEKLEDFASILKETPCIPSSGPSKMLVLPSRLIHPEGRVAKLYNSEDGRFPEGSLRDYVNPVCLVKLLQLGMVKDDLSWEDLIERAESVLALNENDHTIACHRSSIILSLIDEKLKMRDPAANQYLDKFQNIKFLPFLTKPAGFSLPWHGNNFPQLTMFSAKELFTTEHQDTVCLMNPILNENSPSFKGCGPISLAVKDFLGLIRKPTVSLVISQLKELSKSFDG-VTLYQENITNACYKYLHEELLQSNAAKEEIMEELKTFSSILVENTYVEPLKVAFNLNFDAAPYLYQLPNKYRNSCRELFENVGVHASFTVETFSGVLQLIKNECGRKPLTEENFQLSRRIISEGIWSLIRDKSQEFCLSNYGEILLPDSNFTLQPSKSLCYNDCPWIKVRDTTVKYCHGDIPREVAVKLGAIPKRHKALERYASNICFTTLGSEFGQKEKLTSRIKSILNAYPSEKEMLKELLQNADDAKATEIYFVFDPRTHPTDRIFDDKWTPLQGPSLCVYNNQPFTEDDIRGIQNLGRGTKEANPGKTGQYGIGFNSVYHITDCPSFISNNDILCIFDPHARYAPGATSVSPGRMFRDLDSDFRSQFSDVLNLYLGNHFKLERSTMFRFPIRNVEMARISEISSAPASDRMVQNFLDKIRMDGAELLMFLNHMEKISICEIENGTGDLKTLYSVTAKITDGDRLKRKQFHASVLDSVYKKRQLTQIPVQQITYTMDIEDTDGNSTTWLICNRSGFSDMERVSKSVISAHKNEDITLFPRGGVAACTSHNYKKTHRAFCFLPLSLETGLPFHVNGHFALDSARRNLWRDDNGVGVRSDWNNNLMKVLIAPACVELLIQLKRRLFPGPDPTMTIFQGTPIHVVRDILRKYLSFFPVNRLDIQPDWYCLVKAIYLCIHADLKRLLPVVRAPHLDNSDMHSAVYISWVNTSTSTKGKAFFDNLLQDELQHLKNTEYNITTRKSVAENVFRLKAMLLDVGFNLIHSCDETASLYFCLEDAGIPVNYVTPEDVRSFLLTFSSPDTSCQVGKLPCRLQQSNFKLFHGLKLLVDYCFKDVEENDINIEGLPLLMTMDNILQVFDSRHPKFLTTYHELIATRKELFMHTLYIRYSNILIKAGVAKTFDINSFGDLLGSVLPRECKARSSVKWKENFPTESWLKSSWHFISEQLANKDDQAENKLKFETILEILKDWALLPGIKFMVSGNKLVVPEHDVLLPLSLIFAAIFPNGQNDKVFHTLMKGGCFQLAVNKICAKENPMLPLLAQHTANIDNPSSILRALEYMIQISAFKTASLTDKDFDALLLYFNCNLSNLA-QDDIQCLKLLPCYKAVSGRYICISNFGACYVLTKSIPSADIEKWAHNTSSAFLADNPQLKELYGFLGITPIDDLEVYLNHVLPKFDILSHDAKIQHVIYLKERLLAMEEQVSIKDKLFEKLEGLSFIYDSTNRLKPAKAFFDQTVKVFEVMLPQKAFIPNDFFRKIEQVSKPKSGTSYVPSWTTFLRNIGLKYVVSQQQVLQFAKEISIKAHTENWSKEKVQTIVDVLLNHIFNDRTDLFDGTFLKELSMISFLCPERAPAELVHLHAQYQEMNGTVPLIRFSGSQVNPKFKQTDIMQLLWTSCPILPERATPASIKDQEGNTLPSQEQLDLILTMLNVNVEPPLEKVISNCKNICSVTNLDDDTVKTRNKVLRSIYEFLIADKNDFRFQLRGVAFVMVEEGWKLLKPEEVVINLDNESDFKPYLYKLPLELGTFHQLFKLLGTEDIVSTKQYVEVLCRIFRISEGKQLDPNEMRTVKRTVSGLFKSLQNDAVQVRKDLENLRDLIFYLPSHDGRLAKSNTLVFDDAPHYKSRIQGNVGVQMLVDMSQCYLGKDHAFHTKMIMLLPQKLRPRLLSSILEEQLDEESPKMCQFGALCSLQGRLQLLLSSEQFITGLIRIMKHENENAYMVNEEKAIRLCKALCEGLKVSCFEKLQTTLRVKGCSPIPHSRSETLAFLKRYGSAVIHLYIQHSDSKDINFLLALAMTLKSATDNLISDTSYLIAMLGCNDIYRITEKLDNLGVKYDTTEPSKLELPLPGTPIPAEIHHLLLMDPMNVFYPGEYVGYLVDSEGGDILGTYQPTYTYAIIVQEVEREEDDSPSVLGKCFQIDIGYSEYKIVSSLDLYKFSRQDDGTHIRDGTP-TPTSPLEGHSPRARMVPPLFPGKENRRAPPTEAS-PKKVKFNALPEILKEVSSVVEQAWKLSETERKKIIRRLYLKWHPDKNAENLDIATEVFKHLQNEINRMEKQTQAEQTTDRASRRPFSSSSTRFQSEKFSFQRFYTSWNQEATSHKSEKQQ-FREQYNNYAGTSHSNRFFVPPSFKSVGNPVEARRWLRQARANFSAARNDLHKNANEWVCFKCYLATKLALIAADYAVRGKSDKDVKPTALAQKVEEYNTQLTGLAKDVHILEGYGVDSLRTRYPDLLPFPQIPNDRYTSEVAMRVMECTARIIIKLEAFVQQKI", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* * *: * * .*:* *.. . :: . *.:* *: **.:**:**:*::..: : * ::**:*. :::.*:.:* :****************************************************:**.*:***:*** ***.******:****.***:**********::**********************.*******.****** *** **********.* ***.**.***:*:.*::**:::*: :*.****:******::*****.*:*.*:******:**:.************* ***:***:****:::*:**:*:.: : *****:* ** **..*.: *...:**.**::.* .:*::*::***:***********:..:******:***:* **:*:.*: * * :** *.***:******** **** ******:*****************:***********: *::.*:*::* ***:::*:*:: :*..***** ** **:..::: :*:*:* **:.:*:*:.****:. .**::::. **:** .:: : ::::*** ** :*:**. : *: : .:. .:*:*** :***.**** * * : *** ****:***..*.:*:********. *. *****.*:*.:**:* *:****:*.**.*::*:.: **::::*****::* ******:*:*.*** *******:.* **.*:: *** * .:::.*** ***:*:**:***:*::**::*:::****.. * *:**:**: ** ::* :* *. .* * ::::*** .:**::*..::***:*:***.. **::****:: . *:*..*::** .:: ***.***.*** :**********.**.::.:.*. . *. * ***.:**.**** * :::**:.*:*.********.::*:**::*:*.***.:::** :.**::****::*** * ** ***** *:.** .****: :. :: :. ::***::*:*::** ** . *** .::***:******:***** .*:****:***:*** ** .: : * ::******* :***: .*::*** : *:*:****.**:** *** **.*:** **:.: .:*** .:*:*:***:.*** ..::::* : :* :. **:*:* * **: *::*: **:****:** *** **: **.:.::::::*.: ******.*.. . :*:** ********:.:***:***::*** ******:...*: *::.: :.:::::::***:*: *::**:*****.***...: *** : ::****:******* ******:******:*: *******:************************:*************************:********************:****:*::********** ************ ***:**:****** *:** *.***************:**********************.***:*:***********************:***:**.*****::****.*:******.***:***..**:*. ***:**********:******:*** * :* ***** **.**: ***.: *:*. .*** * **:**.***:**. :::. *:*:: ***.**::* ***:*:*****.*********.*:**:: **** .* *:*: :*::.** *: *.**:*:***. *******.:**:********.:.* * * :::*****. *****************:**********************:**: *******:*** .*.:**.:* .*** **:***.****.:*****.:**:*.*::**:* ..: ::*****. ***:*********:* * *:************:* **::*******. ** **::**** *:***::******:****:**:*: :****** :*****:::*:.:*: ***:*.* .: *****************:: :***** ** :**:**: *:**:****.***: *:*::*** ** :*:.**. ** ****:*********::** *::: *:*.* ************* *:**.* ***:*.:::*:*:** ***::******* **:***.:*****:****::****.***.***:::**.*. :***************** ::*.: :* *:::**.*. *****.**:. **:*:***:************:*. *****.***: * *** *: **: *.:* * * :*******.*************:* **** .***:*****:*: * *:*************:*::*****.************:*************:***: *:***************************************** ****** **.********:*****:*************:*******:****.** ***:*******************.**** **************:**********:***:******:****.****:..******:**.***::*****.*:*******:***:* ********************::.** *:.****..*****************:*** *****.:*********** **::** ************.*::*********:*:************* :*****.***********************************************.**..***** ********:* ***.***::::*.******:* *:*:**********:*** ******:* *** *:**********::*.**:**** *:*:* ***.* :.***************::*******:*****:*** :**::****::.*****.**.** ** ***.**** *:****:*******.*::*********:*:****.***********.**.::::******:*:*.:** **.::***********.:**:***:***::**.:*::. ***.***.**.***.****** *::...***:**.:*****.:******.:: .:** * * *: ::: ********* ** ** .:***** ***:****:. *:***.*.*****:***.**:***:****:*:..::***: *****:.*:***:*:.**:* *:*:: .* ::**:***:******.:* ***:: ** *****::****:.*.:**:***********::***::.:***** :: :***** .:* .*:*******:*:***:: **:***::*:****:** : ** . *::******.* :*:*:..*** ** *:*:**:*******:* ***::**:*:**: ***. . ::.**. ********: :****:********::*:*******.:*. **:**:***::* **:.*.******:*.********** :::*.****:***:***:*.*:******** *::************:*** ***:***. * .****: :*.*****::***:***.**:***.:*.**:: **** ********** *:*.:**************:**************: *:********************* ******:*********.***: ****************.*****:*****:*:**.**** *** :****:**:*.**. ****************:*******:*********.****:***:********************:**:**********************************:**::.************ ******************* .*********:*****:*.*** *********************************************** ****.******::********:**********: ********************:***** *:*****************: *..*.*** :********************** ::.:: **.:* ***** * :* * :****.*:*.::. .:: *:*:*.*:********:*********.*:******************.** ***.************:***: :*.:******.**:*::****:*:*******************:** :*: ** ::*:******:******************************************:****************************:***. ** **::*** **.******:****************:************* ****** *:***:", "identical_positions": 3136, "similar_positions": 1046, "identity": "68.19%" }, { "cls_id": "homologset.agr.MGI:1354727", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I6AH70-1", "uniprot_id": "A0A8I6AH70_RAT", "id": "A0A8I6AH70-1", "name": "", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MADEALAGLDEGALRKLLEVTADLAERRRIRSAIRELQRQELEREEGALASKR-----------------------------------------------FRAERQDNKENWLHSQQREAEQQAALARLAGRLESMNDVEELTTLLRSAGEYEERKLIRAAIRRVRAQE---------------------------IEAATLAGRLCSRLPSSGSREDSRRQAAHTLDPGKVPEEEKQGQQTEVREP--TPTPEDTSQDVTTVTLLLRAP-PGGTPSSPAS-----------PDSSPTTASPEPLLEPAGAQCPAAEAPVSSEPLPHPSEAPSPEPPMSPAPPSSQGR------------------------------------------------------------------------------------------VISKPLLGSTEPSDTVDSTRGSSNTKRADLAEPKPCQRS-LSVLSPRQP------------------------------------------------------TQNQEPTPLA-GSSQFRRAGSVRDR-VRKFTSDS------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------PVVARLQDGPPRTALASPTPTRLPGPSLMSTTLASSSSSSNSSSPSPSDTS---------------------SHKKQRELAHSLAQLQSCPQEEGPGGRSLAPRSLENRAGGPRPCSEEPSTPPPVAVGTGEPGG------------SMKTTFTIEIKDGRGQASTGRVVLPTGNQRAELTLGLRAPP------------------------------------------------------------------------------------------------------------------------------TLLSTSSGGKNTITHVSSPG------------------------------------------TVTRLGSVTHVTTFSHASPGNRGGCNFKMEPDPAEPP-SATVEAANGTEQTL---DKVNKGPEGRSP------------------------------------------------LSAEELMAIEDEGILDKMLDQATNFEERKLIRAALRELRQRKR--------------------------------------------------------------------------------------DQRDKERERRLREARARPGESRSNMATTETTTRHSQRAADG-----------------------------------------------------------------------------------------------------SAVSTVTKTERLVHSNDGTQ------------------------------------------------------------------------------------------TARTTTVESSFVRRSENGSSSSSS--TTVQTKTFSSSSSS------------------------------------------------SKKMGSIFDREDQTSSRSGSLAALEKRQAEKKKELMKAQSLPKTSASQARKAMIEKLEKEGSSGSPGTPRTAVQRSTSFGVPN--------------------ANSIKQMLLDWCRAKTRGYEHVDIQNFSSSWSDGMAFCALVHNFFPEAFDYGQLSPQNRRQNFEMAFSSAEMLVDCVPLVEVEDMMIMGKKPDPKCVFTYVQSLYNHLRRHELR-LRGKNV---", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q921U8-1", "uniprot_id": "SMTN_MOUSE", "id": "Q921U8-1", "name": "Smoothelin", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MADEALAGLDEGALRKLLEVTADLAERRRIRSAIRELQRQELEREEEALASKR-----------------------------------------------FRAERQDNKENWLHSQQREAEQQAALARLAGRLESMNDVEELTTLLRSAGEYEERKLIRAAIRRVRAQE---------------------------IKAATLAGRLCSRLPSSGPREDSRRQAAHTLDPGKVPEPEQQEQQTEVLEP--TPTPEDTSQDVTTVTLLLRAP-PGGRPSSPAS-----------PHNSPTSASPEPLLEPAGAQCPAVEAPVSSEPLPHPSEAPSPEPPMSPVPSSSRGR------------------------------------------------------------------------------------------VISKPLPGPTEPSDTLDSIRGFSNTKRADPSETKSCQRS-LSVLSPRQP------------------------------------------------------TPNREPTSLA-GPSQFRRVGSVRDR-VQKFTSDS------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------PVVARLQDGPPRTALASPTPTRLPGPSLISTTPASSSSS-NSSSPSPSDTS---------------------SHKKQRELAHSLAELQSCPQEEGPGGRGLALRSLENRAGGPKPCSEEPSTPPPVAVGTGEPGG------------SMKTTFTIEIKDGRGQASTGRVLLPTGNQRAELTLGLRAPP------------------------------------------------------------------------------------------------------------------------------TLLSTSSGGKNTITHISNPG------------------------------------------TVTRLGSVTHVTTFSHASPGNRGGCNFKMEPDPAEPP-STTVEAANGAEQ-----ARVDKGPEGRSP------------------------------------------------LSAEELTAIEDEGVLDKMLDQTTNFEERKLIRAALRELRQRKR--------------------------------------------------------------------------------------DQRDKERERRLREARARPGESRSNVAT-ETTTRHSQRAADG-----------------------------------------------------------------------------------------------------STVGTVTKTERLVHSNDGTQ------------------------------------------------------------------------------------------TARTTTVESSFMRRLENGSSSSSTTTTTVQTKSFSSSSSSSS----------------------------------------------SKKMGSIFDREDQTSSRPGSLAALERRQAEKKKELMKAQSLPKTSASQARKAMIEKLEKEGSAGGPGTPRTAVQRSTSFGVPN--------------------ANSIKQMLLDWCRAKTRGYEHVDIQNFSSSWSDGMAFCALVHNFFPEAFDYGQLSPQNRRQNFEMAFSSAEMLVDCVPLVEVEDMMIMGKKPDPKCVFTYVQSLYNHLRRHELR-LRGKNV---", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P53814-1", "uniprot_id": "SMTN_HUMAN", "id": "P53814-1", "name": "Smoothelin", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MADEALAGLDEGALRKLLEVTADLAERRRIRSAIRELQRQELEREEEALASKR-----------------------------------------------FRAERQDNKENWLHSQQREAEQRAALARLAGQLESMNDVEELTALLRSAGEYEERKLIRAAIRRVRAQE---------------------------IEAATLAGRLYSGRPNSGSREDSKGLAAHRLEQCEVPEREEQEQQAEVSKP--TPTPEGTSQDVTTVTLLLRAP-PGSTSSSPAS-----------PSSSPTPASPEPPLEPAEAQCLTAEVPGSPEPPPSPPKTTSPEPQESPTLPSTEGQ------------------------------------------------------------------------------------------VVNKLLSGPKETPAAQSPTRGPSDTKRADVAGPRPCQRS-LSVLSPRQP------------------------------------------------------AQNRESTPLASGPSSFQRAGSVRDR-VHKFTSDS------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------PMAARLQDGTPQAALSPLTPARLLGPSLTSTTPASSSSGSSSRGPSDTSSR---------------------FSKEQRGVAQPLAQLRSCPQEEGPRGRGLAARPLENRAGGPVARSEEPGAPLPVAVGTAEPGG------------SMKTTFTIEIKDGRGQASTGRVLLPTGNQRAELTLGLRAPP------------------------------------------------------------------------------------------------------------------------------TLLSTSSGGKSTITRVNSPG------------------------------------------TLARLGSVTHVTSFSHAPPSSRGGCSIKMEAEPAEPL-AAAVEAANGAEQ-----TRVNKAPEGRSP------------------------------------------------LSAEELMTIEDEGVLDKMLDQSTDFEERKLIRAALRELRQRKR--------------------------------------------------------------------------------------DQRDKERERRLQEARGRPGEGRGNTAT-ETTTRHSQRAADG-----------------------------------------------------------------------------------------------------SAVSTVTKTERLVHSNDGTR------------------------------------------------------------------------------------------TARTTTVESSFVRRSENGSGS-----TMMQTKTFSSSSSS-------------------------------------------------KKMGSIFDREDQASPRAGSLAALEKRQAEKKKELMKAQSLPKTSASQARKAMIEKLEKEGAAGSPGGPRAAVQRSTSFGVPN--------------------ANSIKQMLLDWCRAKTRGYEHVDIQNFSSSWSDGMAFCALVHNFFPEAFDYGQLSPQNRRQNFEVAFSSAEMLVDCVPLVEVDDMMIMGKKPDPKCVFTYVQSLYNHLRRHELR-LRGKNV---", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9Q9X3-1", "uniprot_id": "A0A8M9Q9X3_DANRE", "id": "A0A8M9Q9X3-1", "name": "", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSEKRFSSMDESSLRTLLDKTVNIDERRLIRTAIRELRRCEIEEMEAALTSKR-----------------------------------------------FRRANQHRHED--KENQRCPDSTASLDVLSRKIQATRDIEELTGLLRSATEYEERKLLRAAIRRLRDEE---------------------------IRGALES--LGHRTEPPHNPQSSFSLQDNIPTESLISQSVRIGNHRKGSSPDMVLVLDPLVREKVSCPLTPRIERDHGSSSSEVI-----------PSYRERSDSGESSDSHRSHQRKRLNSSASDQEHSHDTLRDRS----SPSGPAGDEV------------------------------------------------------------------------------------------SSETPLISGINSEAPQSDQQRKKLENGLDSSHFRSTAASQESTLSSKRP------------------------------------------------------DDSSRLKASSGRDSFLTSLTNGKDTDFRNKTSYS------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------GPFIRTNSVRDRMLKFTEPVSSAPRSAHSFSHSTNTVSADESRDTLSCSSS---------------------IPKKGRNVSESMMSAQPKLLSSQSRAAVGGSETRSQNVRSACGFSEEVQTPEGESS-AGAHHS------------SMKTFLSIEIKDGRNPPSHS---------------SLSSSS------------------------------------------------------------------------------------------------------------------------------TAVNMSP---RIITAAAPQR------------------------------------------TELTLG--LRATPFKVTSSSLSSGSSVKMETEPVSLVGESVIETSHDVPVLPNGSSMTSIKTEAQSEK-----------------------------------------------LTSEKLRDIEDEEILDKMLDECKDFEERKMIRTAMRELRKKKREAK---------------------------------------------------------------------------LGCTQEEMDQREKERDQRLLELRQQREDRCKKADGSNVLIKKTERSADS-----------------------------------------------------------------------------------------------------STVSHITN--RISHTDDAGR------------------------------------------------------------------------------------------TSRSTIMESSYIQKTDKG---------TTQTKSYSYSSTTS-----------------------------------------------TRKVGSVFDREDNTSRSSSRSSALDRRQAERS-ELMRAQTLPKTSAAQARKAMIEKLEN-TSGNLAIAQVNRVQRSTSFGVPN--------------------ANSIKQMLLDWCRSKTRSYENVDIQNFSSSWSDGMAFCALVHNFFPEAFDYSSLSPTNRRQNFETAFSTAEAYANCMPLLEVEDMMIMGKKPDSKCVFTYVQSLVNHLRRCEMMRARAQQTSDF", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "M9PDW8-1", "uniprot_id": "M9PDW8_DROME", "id": "M9PDW8-1", "name": "Calponin-homology (CH) domain-containing protein", "aln": "MEVECDLGDIQNEELLRKMWQQSEDSERKRQIRSHLYKLRESRLCNLYRHETDPMSEPNGNGHGNVNTLAGYAGKDPLATSHGDALLDQNFQSLKSKEVRDSTSPTHELRFHSMTLSQPNTTGWDVQTSSEVSPDGRAYRTETLAKTDGVEKLNGGGLAEFKGRNEQRSSASHQGDDKNFVKQASDSSKTQLQETVVFGDETSGRTEMKMSSTSTSSSSKVVSSSSTVEYGDEPRYLLDNQEKPHKQHQTREWEQDQRRQEQRIQEQRQEQQIRQEQLQRQEEFQRQEQIQRQEQIQRQEQVQRQQERFTESREQSNSTRNVQTQQHYEENKRYVDMDKASPEYQRHVQHLMEQPGEIISNTVEYPKPNVKMITTVKRLPDGTIVKNKRYETEQLTPSQSHTTHKQTNNQTHNQTRNQVHNQRREQDEQDSQTRDVVDNVEQKHVTESQSFSSVKKSSRRFSTETTSETVEEYDDRDQPTSRVVQKAPTPSYAPPSHSPRQSPAKDFSTHGFPSVRPNKATQEYPSQRPGIAGEEVVVVRSEKSRQVKQQTSSQRTIETEVVGDDYQEPQRSPQKLREAPTPSWEQPATRRQPVEEDFSTHGFPSVRTTTTSTRPDQPDGEVLHTSKTVSRNQSANRKTNTERIIETQVEHPNAPSHSTPRSGSPRRSQPRDDYASSPRGPAGKPSQSRPSNTGGSTTTKTTTTSEPLTRRQLQKEREVDAAHRAFAASLRSSSPADSTTSVGSHHQTPRSSVSSNRTFRREMREGSHDSQAPSESSRISSTTVTRHTTGGNVTSNTIKTKTTKPVKTASEPRSPTPKAGGSVTTTTTTITTKSSPSPAPASPTTAAPPTSAPASSAPPDNKLSQYTYTTTKPGDIFSLPPTTPPTINNEPTLTTTRNTTTTTTTTTTATSDNLQNHPKKSAIEPATDTDSQPIRKVKLSANEAKVVEEAPCVRRQYYQLGNEGENPETPESSGTPANKKPHQMRRPHDEPEPQLRRSSKSPSVEPRQVQRETTFEGRRVSQDREISIDELILIEETSGAPGSPKIPSPRAQSPGKPATRSQSPEKPQPRATPRQSPEKEQPAFKQTHEVYTPSQPEKQFPRARSPEKTPGWTQPQVSPRQSPEKQLPRAQSPEKVPAVRQPSVSPRQSPEKQIPDPKTRDQGPGLPRISPRQSPEKQLPKDVPQKSRQSPEKDLTNQQRREEEIFRSTITTTQKRTTNNLNEEFITNERDNQNQPISEKKPQIPANAEPNTKPSETIESPDGGFPSKTTEVEAQPEVKESPTYRKKGLTRRETFEDRCRQILGMEEDGDTQGTYTERPNNEQEDVNVSHTTIETIQVKIEDCPNDDEDDKPRRVTETYVVRTQPKIKVEEELFVDVTEAEDVEILVNPSKKSPKEEDSPKYPKGPETPKSPRNDQRIPSIPKKGQSPVQFKTEETPRYPQEQERYPKEPETSQYPKESPRNPKEDAETININEETTIVITKEGSKSPSPRWSPSPERRVPKSQQPPSPTASPSVSPVSGRKIPNEVESNFVTEKIIDCRGKTVVEKISQRPRTPSPTTPKKNTKPSQKIPERVPETESEPEKDSESETKKTTSVSVTKTETERRNSRTTKTKQPLPLKEPQSKVPAGKSPRKDSLTGRKRDSLVEETRITTTTTTTRQGRKPSDTNGSPSIKDRLRSSPRKQKTSPQQTRTPTPAQTRNPEDDVDGDSSSPDASPTRVGNERRRSSNISVHTEIIIDHMAPKSPKTERRSQGGTGNVPSPIRKLPVTERKESAPVPRVTRRDKAEKVTRSTSENIIKMSGTKPHPEMSSLKPGGDRSRPSKCCTTKTINLSEQRINTATDIEGVIIDIQQAKSSREPSPDRIVPTPVPAELETGKPRYPDVVQEPDDEPRRKPQVTNIPIFEEESQTYVGCQISELHSSNGIEVDILDNPTVEAPKSLDYPVNTPDTDESLLSVHEKVSRFTHSAEKVKEPKVSAPFSREFDVNAKIPENDDCLLSINQKVDKFLRTAENVIRPTSLPSRPEIERPGLEEIDEELLRDDCTLSVSQKVHKFIDTAEKLAPTMPQKSPRLVANIERHISRQSEPERELDEESEPELDRDTDVEDDDQTSQLETEEEITQTVTKKETLKEFKQQTKETRETRRDSKAEPEKLQKKSPQTKVKEESARVPKYQAKVSQKVSQWEPKKQPQREPKVTQKETPLEPKKQPLSKVKDEPEKVNKREPKVPQKESQTKLKEEPERVTKKTPQKEPRKEPLRQSEDEPEFSPEEEFDDEPLPMTKTHTTAIEMKRQKDILNRPSVFGQRTPERKSSTTPSPTKLNGTRGRPSPSTNLITEEKRSYRNQVTNVSKPGTRKTTPSANSPAQSPPPKTTSISKRMEQISQQSWVVQDVDVDVEVVGPAPPSHISEKPQGKSPSPTSSRSLSRSPSRSPSRRTSTNLNTTSTNTTTTTEHPSTIKTTTPKPTSTNPSKDEPEIIPIESLTEKSITTTYTTNTTGRNVASRRNVFEPVHETHVDSEPTGRRPSYMDHTKSSLEHIRRDSLEINKSHYSRKSSMEDDSPVEPRNPNSSVKFDVPRKSSSRGADEPRKTSLKGKDEDSDLELEIEEIFDLQRLEKLLETVASYEMRRRIRAQMRLIRKNMINAGTTTTITTITTSTTPGKSSPLPKIRRDQSPAGAAEVKTKEVRTTTSRRQQQQRVEQVDSTTPIAPGKTSPHGKPPVKPRERSASPAQKRRISPPGKQSPGDRSTTTTTKVTTTSTTRGAPSKPAQGPIWADRSKVLKGHATVPQTNGSTPRKGSTSSTTSSSGKITRTMTSSSTTTSSSSTTNTRNKQREEDSITSSYGVGPTDENGLPLFGIRALKKKATPPAEEPCETKQEVTGYVIEEQFYSDNKSPPRHERKELIYSSNADELAAIKQQLQDEDDSSPPLLDARVVREFKKVESQQSLPEDARYVRRGSVKELSEKFIRKESSSSTHSTHSSIAQSLVRHEDETEDDSESNDVCSVIEAPQMRQNQSHTMSTTRSSNTRSFLNSSADQRQVTSVDDVLERMRNADNVEEPGDSSEDREARALLNKFLGASVIMQGVESMLPPTATGQRLNSQGVKTTRITNTYSKSGNSTSTTNNTSNTTNKVSSSSAPVTRTTCDIEEIWDEQVLKQLLEQASTYEERRKIRARLRELMAEREEQKNLKQAPKEEKEEEESSASEYEEIIEEVTDYSDEEEEVPPKKEEPKKEEVTKKEVTKKEVTTKQQEEIQQKAVKKVEKTETKTSQATESVSKKLAKVELASSSSSSTTDGVQVQGESLPAKATKTGATGAAGPVSSSSIGSRKSSSLSSSQVSTVVRARDKAKPEMMPVAGTGSGSESVPGSGAPNTGSRLSVPSKEDSGTESGEDLRLLAAGLRDTLQQQSGSDASEANRSLVEEVTDALSRLESSLKQGKELAVDGGQRQALLGLVARLQSGLSAPEKLAEDRKTDECQKEVETGSPEPDGDSRQSRFAKRRQRNSRHTVGVSREELADARRYMEDMLILEGKDFALSKTPSSSAVPVQLYRPNQFVAQSQQPQSVNNQPNATQALPTQNQSQLRPNTSNRRPLSGDYAVSFASYEANQNSQNSSPEGNGNSASNSQSNSNSSSNSSRFGGGKKHLMKRANTIDIPKAKAKYMADCDSDSDLEDDHGPHLGLKRAVQVSVKRRVHNAVPPFEPKTENDHKFLAFINKQSHQTGLGWSGGGGRSVSNWTHKFGNIKHTFETGAAATVTKGKPPPVPGHVPGWAKQEQLHHQQLQREQMQREQMQREQYQREQRQREQRELREQLQREQYQREQSQRDQNQRELSKREQFQREQLQREQLQREQLQREKLQREQLQREQLQREQLQREQLQREQLQREQLQREQLQRDQLQLQQQQQAAAAVQIERQRRQELERQLRLEQEARFEREERTRLEREYYEQQLQRQQVERQQQLDRQRQQQEQMERQRRQEMELRLQQQREQAAQVNNFIHAPQSVFRPIENETQPQPGIYKPIAHKSQPNPAVWKPPTQQSQPPQQSQQHLQPRSATTYSNTPSPSSTATSPIGLPWVAKPKVDNSDFRRKAHHFEERSLRDNIEQQQQPTYPNGNNGYLQRHNSLRSKAPALSEFKKRPSLPNAMDPGTAAPPRQVYQAPPPPTNISFTYADFPPVRRPQGASAHNYRSQPCLTSAVDQVEALTNPLGAPLVLTSSNPTYLPPPGSRRFDYISSPVDVDADSPPNSPTSFMTMPNPTLMTDNTDDDLDLDSDNNMLEYRAETKVMRKPRSQTAVRVADRRNAHMSDDEVYGKNSRAAKSLLYTMKQLGGGPGNASVGNSGQRRQPLTAPSSPKSGCLSPDGRPYQAPLVEPLFPQLSTFEPKRQPQFANSPMSTPPAVSMPSINYQANPTYTPPRSNQNSNSYLGETNTSYVVTYPLDDSGDEPEPESMATSVSQRLRRTSEHSNASSSLSLGSTSWTANPVHNTVPSVPLDSAMGPPVDRSTKPQVSQPVGPKMPQHVAQKQIPQQLPNQLPQQIPQQLPKQLPQQIPQQLPQQLPQQLPKQLPQQIPPQLPKQLPQQIPQPELPQQLPNNLPRHAPKLSSRSHTIQGDSGYENRPLQNRVMSQQTLNSSIITSNNHTTVQKQQKEQHINELRRKSLGNVLESSQRSTYFEQEYKSSAPPDTPDIVKSSLPKEDAPLLKKFGPPQRHHYMPNSYQSPQLNKQGNSNSTTTSSTSVRSTTVVQQQHHQQQHQQIKPSIVETPATPQPQVPPEDEIPHNIVFNNVSAFTSMSRRNHEEDSHQGTQSGSRVNRLSKCDSWNQICQLQQTAGPSPAKYNQPGSPGELRRTKSGHSLAVPKLYEAGIDKAQVSEKQRTVAAYFSGQKSPTGGQVEELRTSMTTTTSSRKSAINRTKTSEKLSAAARKSLSSLTTTSNGNVSTAGLGMVVRGGGVGGIGGGAALSRSATMPHIANLNLLDESNVEDAFEQLMMAQHKSSSSSEQRTETKSKDGGATVTTTTTKVTTRTVSGSAASKNISPLAKFKQLDKQAAAQQAQKSSPTTSTPTTPGGSAQPLFKFTDPALNARAATVKDQLLQWCKHKTQEYENVQINNFSSSWSDGLAFCALIHHFLPDAFDYTTLTKQTRRHNFELAFSVADEKAGIAPLLDVEDMVEMSR-PDWKCVFVYVQSIYRRFRNCQ------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .. :: .. *.:*: :.: : : .:..::. : . :..* :: : :: ... *.: : :: * : *. **..* ****: :** :*.: :. *. . .. : :. . : : . . : . .** . . . . . * : . . * : . . . : . : : . .. * * :: :: . . . . . .: .: ** : .. . : : .: : .: .. : : * : . : . : . . .. ... . .:. * :. *:. :: :. .: . .* . : :. * :* . : : . :.. ... : .. :: : . .. . * : .: : :: : ::: :: : ::: : ::: :: :.::::::: * * : : .. .: ::: . *. .*. * * :*. : *:: :: :: . *: * ::: . .:: :.::* . : . ::. . :: .:* :..* . *. * : . : *.: ..*. * ::*: **:**: **: **:*:*:*********:*****:*:*:*:**** *: .**:*** *** *: .. **::*:**: *.: ** ****.****: .::*. : ", "identical_positions": 109, "similar_positions": 288, "identity": "2.1%" }, { "cls_id": "homologset.agr.MGI:1354730", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P49758-4", "uniprot_id": "RGS6_HUMAN", "id": "P49758-4", "name": "Regulator of G protein signaling 6", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MAQGSGDQRAVGVADP----------EESSPNMIVYCKIEDIITKMQDDKTGGVPIRTVKSFLSKIPSVVTGTDIVQWLMKNLSIEDPVEAIHLGSLIAAQGYIFPISDHVLTMKDDGTFYRFQAPYFWPSNCWEPENTDYAIYLCKRTMQNKARLELADYEAENLARLQRAFARKWEFIFMQAEAQVKIDRKKDKTERKILDSQERAFWDVHRPVPGCVNTTEMDIRKCRRLKNPQKVKKSVYGVTEESQAQSPVHVLSQPIRKTTKEDIRKQITFLNAQIDRHCLKMSKVAESLIAYTEQYVEYDPLITPAEPSNPWISDDVALWDIEMS-KEPSQQRVKRWGFSFDEILKDQVGRDQFLRFLESEFSSENLRFWLAVQDLKKQPLQDVAKRVEEIWQEFLAPGAPSAINLDSHSYEITSQNVKDGG---RYTFEDAQEHIYKLMKSDSYARFLRSNAYQDLLLAKKKGKSLAGKRLTGLMQSS", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P49801-1", "uniprot_id": "RGS6_RAT", "id": "P49801-1", "name": "Regulator of G protein signaling 6", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------LAVQDLKKQPLQDVAKRVEEIWQEFLAPGAPSAINLDSHSYEITSQNVKDGG---RYTFEDAQEHIYKL----------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9Z2H2-1", "uniprot_id": "RGS6_MOUSE", "id": "Q9Z2H2-1", "name": "Regulator of G protein signaling 6", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MAQGSGDQRAVGIADP----------EESSPNMIVYCKIEDIITKMQDDKTGGVPIRTVKSFLSKIPSVVTGTDIVQWLMKNLSIEDPVEAIHLGSLIAAQGYIFPISDHVLTMKDDGTFYRFQAPYFWPSNCWEPENTDYAIYLCKRTMQNKARLELADYEAENLARLQRAFARKWEFIFMQAEAQVKIDRKKDKTERKILDSQERAFWDVHRPVPGCVNTTEMDIRKCRRLKNPQKVKKSVYGVTDETQSQSPVHIPSQPIRKTTKDDIRKQITFLNAQIDRHCLKMSKVAESLIAYTEQYVEYDPFITPAEPSNPWISDDITLWDIEMS-KEPSQQRVKRWGFSFDEILKDQVGRDQFLRFLESEFSSENLRFWLSVQDLKKQPLQDVAKRVEEIWQEFLAPGAPSAINLDSHSYEITSQNVKDGG---RYTFEDAQEHIYKLMKSDSYARFLRSNAYQDLLLAKKKGKSLAGKRLTGLMQSS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9VXA3-1", "uniprot_id": "Q9VXA3_DROME", "id": "Q9VXA3-1", "name": "", "aln": "MVTMNSEADKTQATNASSTAAPAKTDCTSSNSSDPLAVAIPEPQSATAVVGGGAGGAAPGTATPSPTPLANGSNNGTGSSVSPAATGTGAVATAASAPAAAGTTSASPPASNPTTASTSTASVVGAKTAAATTTSSSSATSSSTAAAGSKQSGSSGGLLTVSGNHHHHHHAHPQQSAAGQSAAQPPQPPTATALAVPSASHHQRGGKNEDAPNILVYKKMEAIIEKMQAESTG-VAVRTVKAFMSKVPSVFTGADLVAWILKNFDVEDVTEALHFAHLLSSHGYIFPIDDHALTVKNDGTFYRFQTPYFWPSNCWEPENTDYAVYLCKRTMQNKTRLELADYEAENLAKLQKMFSRKWEFIFMQAESQSKVAKKRDKLERKVLDSQERAFWDVHRPMPGCVNTTEIDIKKAYRRGGSSHGTGSAG----------------ASLAKNPVEQLTRIIALRKQKLERRTIKVSKAAEALVAYYDQYNEFDYFITSPELPNPWQTDSTEMWDTEKNSKEVPVRRVKRWAFSLRELLNDAIGREQFTKFLEKEYSGENLKFWESVQEMKALPQSEIKEAIQKIWQEFLAPEAPCPVNVDSKSVELAREAVNSPSGPNRWCFDVAASHVYHLMKSDSYSRYLRSDMYKDYLNCSRK-KIKSIPNLFGVKR--", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :**::* * .:: : :::******** **..:*:**:* *:: : *:. . *: *: * .*:*:* ", "identical_positions": 26, "similar_positions": 26, "identity": "3.9%" }, { "cls_id": "homologset.agr.MGI:1354731", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q4KLI9-1", "uniprot_id": "FBXW5_RAT", "id": "Q4KLI9-1", "name": "F-box/WD repeat-containing protein 5", "aln": "-----------------------MDEG-------GMPLLPDSLVYQIFLSLGPADVLAAGLVCRQWQAVSRDEFLWREQFYRYYQVARDVPRHPAATSWYEEFRRLYDMVPCVEVQTLK-------EHTDQVLHLSFSHSGYQFASCSKDCTVKIWNNDLTISLLHSADMRPYNWSYTQFSQFNQDDSLLLASGVFLGPHNSSSGEIAVISLDS--FALLSRVRNKPYDVFGCWLTETSLISGNLHRIGDVTSCSVLWLNNAFQDVESENVNVVKRLFKIQNLNASTIRTVMVADCSRFD-SPDLLLDAGDQAGLPCRVFDLGGD---TEEEATDPGLHTSGSGHVKEGLR--RVFDSVLDG--HGQLSDCALETKVAELLAQGHTKPPECPDAD----------------SRNKYLIFTTGCLTYSPHQIG---IKQILPHQMTTAGPVLGE----GRGSD--------------------AFFDALDHVIDVHGHIIGMGLSPDNRYLYVNSRAWPPGSVVADPMQPPPIAEEIDLLVFDLKTMREVKRALRAHRAYTPNDECFFIFLDVSRDFVASGAEDRHGYIWDRHYNICLAKLRHEDVVNSVAFSPQEQELLLTASDDATIKAWRSPRIVRVLQAPHPRPRP----FFSWFASHRR", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9QXW2-1", "uniprot_id": "FBXW5_MOUSE", "id": "Q9QXW2-1", "name": "F-box/WD repeat-containing protein 5", "aln": "-----------------------MDEG-------GLPLLPDSLVYQIFLSLGPADVLAAGLVCRQWQAVSRDEFLWKEQFYRYYQVARDVPRHPAATSWYEEFRRLYDMVPCVEVQTLK-------EHTDQVLHLSFSHSGYQFASCSKDCTVKIWNNDLTISLLHSADMRPYNWSYTQFSQFNQDDSLLLASGVFLGPHNSSSGEIAVISLDS--FALLSRVRNKPYDVFGCWLTETSLISGNLHRIGDITSCSVLWLNNAFQDVESENVNVVKRLFKIQNLNASTIRTVMVADCSRFD-SPDLLLDASDQAGLPCRVFDLGGD---TEEEATDPGLHTSGSDHVKKGLR--RVFDSVLDG--HGQLSDCALETKVAELLAQGHTKPPECNDAD----------------TRNKYLIFTTGCLTYSPHQIG---IKQILPHQMTTAGPVLGE----GRGSD--------------------AFFDALDHVIDVHGHIIGMGLSPDNRYLYVNSRAWPPGSVVADPMQPPPIAEEIDLLVFDLKTMREVKRALRAHRAYTPNDECFFIFLDVSRDFVASGAEDRHGYIWDRHYNICLAKLRHEDVVNSVAFSPQEQELLLTASDDATIKAWRSPRIVRVLQAPRPRPRPRPRPFFSWFASHRR", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q969U6-1", "uniprot_id": "FBXW5_HUMAN", "id": "Q969U6-1", "name": "F-box/WD repeat-containing protein 5", "aln": "-----------------------MDEG-------GTPLLPDSLVYQIFLSLGPADVLAAGLVCRQWQAVSRDEFLWREQFYRYYQVARDVPRHPAAMSWYEEFQRLYDTVPCVEVQTLR-------EHTDQVLHLSFSHSGYQFASCSKDCTVKIWSNDLTISLLHSADMRPYNWSYTQFSQFNKDDSLLLASGVFLGPHNSSSGEIAVISLDS--FALLSRVRNKPYDVFGCWLTETSLISGNLHRIGDITSCSVLWLNNAFQDVESENVNVVKRLFKIQNLNASTVRTVMVADCSRFD-SPDLLLEAGDPATSPCRIFDLGSD---NEEVVAGP-----APAHAKEGLR--HFLDRVLEGRAQPQLSERMLETKVAELLAQGHTKPPERSATG----------------AKSKYLIFTTGCLTYSPHQIG---IKQILPHQMTTAGPVLGE----GRGSD--------------------AFFDALDHVIDIHGHIIGMGLSPDNRYLYVNSRAWPNGAVVADPMQPPPIAEEIDLLVFDLKTMREVRRALRAHRAYTPNDECFFIFLDVSRDFVASGAEDRHGYIWDRHYNICLARLRHEDVVNSVVFSPQEQELLLTASDDATIKAWRSPRTMRVLQAPRPRPRT----FFSWLASQRR", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VMI1-1", "uniprot_id": "Q9VMI1_DROME", "id": "Q9VMI1-1", "name": "", "aln": "MEVTFKKARLGKERLVEQSEEEERDEGSSGQDLFGWWALPEPALLMIFERLSVPDLLRASRCCVRWHSIAKDDLLWRHKFQEHFKASPSIPLKPGSESWRAEYKRLSMHIPFVQAQRLEPTVENNHGHTHQVLHVSFAHNGEMFATCSKDGYVIIWNAQHPCSEKYAHNMKQFSWKYSQYSQFNQSDTLLLVSGVHFGSPQSTSGEIAVFYLGATESHLRCRVVNRPYDIFGTWFSDQYLISGDLHWLAHLVSTSVLWLNKANQEIDSEHVPIMSQLYKFYNRNASSVRAIMVARCPWLDESNDPLATTADQESHSSVLSPPTGDQGSTSQASGNPVSHAASILRTRSSTPEENYLPDISERRSRARLGDATIHYLDEYRTAVATTNESNDDDDEEYDSMDVQEEYDEMENSIPKYLIFSTGSTTFTPHQIGFKRIRNVFFPKKLDPGPSLKERIAAKRAAEQQQQQTPRTDPDWWDYESVKDRFDKVDKVIDLHGHIIGMALSPDHRYLYVNTRPWPKNYVITNPLEPPPIAQEIDIHVIDLMTLKRVGNMLRAHKAYTPSAECFFIFLDVCEEYVASGAEDQHAYLWDRYYGISLAKFKHSDVVNSVAFNPRDSEMLVTTSDDYTIKVWRSRAKAKEFNIPINVSES-----FELKPKN--", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *** * **:. : ** *. .*:* *. * :*:::::*::**:.:* .:::.: .:* :*.: ** *::** :* *:.* *. **.****:**:*.* **:**** * **. : . * :: :*: :.*.*:*:****:.*:***.***.:*. :*:******: *.: * .** *:***:** *::: ****:** :..:.* ******:* *:::**:* ::.:*:*: * ***::*::*** *. :* * * * :.* .. : .* ..: .* . :.:.. . : : : : :*.: :. * . *: .: : *****:**. *::***** *:::: : .** * * *.:: ** :*:***:*******.****:******:*.** . *:::*::*****:***: *:** *::.* . ****:****. *********..::*******:*.*:***:*.*.**:::*.******.*.*::.*:*:*:*** ***.*** : :: * ... *. ..: ", "identical_positions": 238, "similar_positions": 192, "identity": "35.9%" }, { "cls_id": "homologset.agr.MGI:1354732", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q701N4-1", "uniprot_id": "KRA52_HUMAN", "id": "Q701N4-1", "name": "Keratin-associated protein 5-2", "aln": "MGCCGCSRGCGSGCGGCGSSCGGCGSGCGGCGSGRGGCGS-------------------GCGGCS------SSCGGCGSRCY-VPVCCCKPVCSWVPACSCTSCG-------------------------SCGGSKGGCGSCGGSKGGCGSCGGSKGGCGSCG----------CSQSSCCKPCCCSSGCGSSCCQSSCCKPCCCQSSCCVPVCCQSSCCK-------------------PCCCQSNCCVPVC--------CQCKI", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q701N2-1", "uniprot_id": "KRA55_HUMAN", "id": "Q701N2-1", "name": "Keratin-associated protein 5-5", "aln": "MGCCGCSGGCGSGCGGRGSGCGGCGSGCGGCGSGCGGCGS-------------------GCGGCGGCGSGCAGCGGCGSGCC-VPVCCCKPMCCCVPACSCSSCGKGGCGSCGGSKRGCVSCGVSKGACGSCGGSKGGCGSCGGSKGGCGSCGGSKGGCGSCGGSKGGCGSYGCSQSSCCKPCCCSSGCGSSCCQSSCCKPYCCQSSCCKPYCCQSSCCKPCSCFSGCGSSCCQSSCYKPCCCQSSCCVPVC--------CQCKI", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q64507-1", "uniprot_id": "KRA51_MOUSE", "id": "Q64507-1", "name": "Keratin-associated protein 5-1", "aln": "MTCCGCSGGCGSSCGGCGSSCGGCGSGCGGCGSNCGGCGSSCCKPVCCCKPVCCCVPVCSCSSCGGCGSSCGGCGSCGSSCGGCGSSCCKPVCCCVPVCSCSSCG----------------------GCKPCCCQSSCCKPCCSS--GCGSSCCQSSCCKPCCCQSSCCKP-CCCQSSCCKP-CCSSGCGSSCCQSSCCKPCCCQSSCCKPCCCQSSCCKPC---------CCQSSCCKPCCCQSSCCKPCCSSGCGSSCCQDSC", "tax_id": 10090, "tax_name": "Mouse" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* ***** ****.*** **.*************. ***** .*..*. ..**.*** * .****:*. **.***:*** .* ... * .* .* ****. ... * .* *.******* ****************** ******* * ******** ******.** * * ** . ", "identical_positions": 118, "similar_positions": 29, "identity": "44.53%" }, { "cls_id": "homologset.agr.MGI:1354733", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q925A6-1", "uniprot_id": "Q925A6_RAT", "id": "Q925A6-1", "name": "", "aln": "MPNDDAFGKPSAPTEVPHAPGAPPQGKAGGYSKATGAMAGAAGGSSAGGS--GGASGSGPSGLGSGSKKSPRLPKCARCRNHGYASPLKGHKRFCMWRDCQCKKCSLIAERQRVMAAQVALRRQQAQEEELGISHPIPLP-SAAELLVKRENSASNPCLMAESSSSAQPPPASTPTPTVSEG-RMVIQDIPAVTSRGHMENAPDLMSDPAYYSSFYQPSLFP-YYNNLYNYPQYSMALSAESSSGDVGNPLGGSPVKNSLRSLPAPYVPAQTGNQWQMKTSEGRHPVSSQYRMHSYYGPPSYLGQSMSQIFTFEEGPSYSEAKASVFSPPSSQDSGLVSLSSSSPMSNESTKGVLECESASSEPSSYAVNQVLEEDEDE", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9QZ59-1", "uniprot_id": "DMRT1_MOUSE", "id": "Q9QZ59-1", "name": "Doublesex- and mab-3-related transcription factor 1", "aln": "MPNDDTFGKPSTPTEVPHAPGAPPQGKAGGYSKAAGAMAGAAGGSGAGGS--GGASGSGPSGLGSGSKKSPRLPKCARCRNHGYASPLKGHKRFCMWRDCQCKKCSLIAERQRVMAAQVALRRQQAQEEELGISHPIPLP-SAAELLVKRENNASNPCLMAENSSSAQPPPASTPTPAASEG-RMVIQDIPAVTSRGHMENTSDLVSDPAYYSSFYQPSLFP-YYNNLYNYPQYSMALSAESSSGEVGNSLGGSPVKNSLRSLPAPYVPAQTGNQWQMKTSESRHPVSSQYRMHSYYGPPSYLGQSMSQIFTFEEGPSYSEAKASVFSPPSSQDSGLVSLSSSSPMSNESSKGVLECESASSEPSSYAVNQVLEEDEDE", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9Y5R6-1", "uniprot_id": "DMRT1_HUMAN", "id": "Q9Y5R6-1", "name": "Doublesex- and mab-3-related transcription factor 1", "aln": "MPNDEAFSKPSTPSEAPHAPGVPPQGRAGGFGKASGALVGAASGSSAGGSSRGGGSGSGASDLGAGSKKSPRLPKCARCRNHGYASPLKGHKRFCMWRDCQCKKCNLIAERQRVMAAQVALRRQQAQEEELGISHPIPLP-SAAELLVKRENNGSNPCLMTECSGTSQPPPASVPTTAASEG-RMVIQDIPAVTSRGHVENTPDLVSDSTYYSSFYQPSLFP-YYNNLYNCPQYSMALAADSASGEVGNPLGGSPVKNSLRGLPGPYVPGQTGNQWQMKNMENRHAMSSQYRMHSYYPPPSYLGQSVPQFFTFEDAPSYPEARASVFSPPSSQDSGLVSLSSSSPISNKSTKAVLECEPAS-EPSSFTVTPVIEEDE--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q71MM5-1", "uniprot_id": "DMRT1_DANRE", "id": "Q71MM5-1", "name": "Doublesex- and mab-3-related transcription factor 1", "aln": "MSEEE---------------------------QTNGSLS---------------------------IRKPSRMPKCSRCRNHGFVSPLKGHKRFCNWRDCQCQKCRLIAERQRVMAAQVALRRQQAQEEEMGICSPINL--SGSDTLVKNEAVGEN--VFTLSSGPPSPASSSATASPTNLGSRSMLSLSPAMSSRGHTDCTSDLMVDASYYN-LYQPTPYSSYYSNLYNYQQYQMP----SGNGRLSS-----------------------------------HNVSPQYRTHSYYS--SYLSQGLGAACVQP--STCPEPKAAAFS-DGAQDS--VSISS---MINAENK--LECESSS-ESGSFSVDSIIEGATK-", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VDF1-1", "uniprot_id": "Q9VDF1_DROME", "id": "Q9VDF1-1", "name": "", "aln": "MASSSGEPADEVANKRPRLVANP---------KATKIVEPTP------------------------AKVTNRVPKCARCRNHGIISELRGHKKLCTYKNCKCAKCVLIFERQRIMAAQVALKRQQAVEDAIAMRLVANKTGRSIDALPPGNIFGLTVTQPSSPRAKREDDQVEKTISEVEQQHLKQREEEYSESPAVAQDLSAPRRDNVSQTAIDMLAQLFPQRKRSVLELVLKRCDLDLIRAIENVSPTGKSSPVDVTSNQLP---------------------SQEPGMLTTMPQPAPPRSSAFRPVITDQYQSKSVVELKPPVFGGSASAAAAAAICAYPKWFVPLSFPVTMGHLSNLAPRCTLPNCACLDSYQFH", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*.... :: : : . *:***:****** * *:***::* :::*:* ** ** ****:*******:**** *: :.: . : * : . . : . . . . . .. . : :. : :. : : . :. .: : . :. .. . . : * :...*. .: : . : : . : . : . :: ", "identical_positions": 42, "similar_positions": 78, "identity": "11.08%" }, { "cls_id": "homologset.agr.MGI:1354734", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9DC04-3", "uniprot_id": "RGS3_MOUSE", "id": "Q9DC04-3", "name": "Regulator of G protein signaling 3", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MNRFNGLCKVCSE---------------------------------RRYR-------------------------QITIRRGKDGFGFTICCDSPVRVQAVDSGGPAERAGLQQLDTVLQLNERPVEHWKCVELAHEIRSCPSEIILLVWRVVPQIKPGPDGGVLRRASCKSTHDLLSPPNKREK-NCTHGAPVRPEQRHSCHLVCDSSDGLLLGG---------WERYTEVGKRSGQHTLPALSRTTTPTDPNYIILAPLNPGSQLLR---------------PVYQEDTIPEEPGTTTKGKSYTG--------LGKKSRLMKTVQTMKGHSNYQDCSALRPHIPHSSYGTYVTLAPKVLVFPVFVQPLDLCNPARTLLLSEELLLYEGRNKTSQVTLFAYSDLLLFTKEEEPGRCDVLRNPLYLQSVKLQEGSSEDLKFCVLYLAEKAECLFTLEAHSQEQKKRVCWCLSENIAKQQQLAAPPT----ERKMFETEADEK-EMPLVEGKGPGAEEPAPSKNPSPGQELPPGQDLPPSKDPSPSQELPAGQDLPPSKDPSPSQELPAGQDLPPSKDPSPSQELPVGQDLPPRKDS-SGQEAAPGPESPSSEDIATCPKPPQSPETSTSKDSPPGQGSSPTTELPSCQGLPAGQE-STSQDPLLSQEPPVIPESSASVQKRLPSQESPSSLGSLPEKDLAEQTISSGEPPVATGAVLPASRPNFVIPEVRLDNAYSQLDGAHGGSSGEDEDAEEGEE---GGEGEEDEEDDTSDDNYGDRSEAKRSSLIETG-QGAEGGFSLRVQNSLRRRTHSEGSLLQESRGPCFASDTTLHCSDGEGATST-WAIPSPRTLKKELGRNGGSMHHLSLFFTGHRKMSGTDLT-ECDE-ASRKRKSKNIAKDMKNKLAIFRRR-NESPGAQPASKTDKTTKSFKPTSEEALKWSESLEKLLLHKYGLEVFQAFLRTEFSEENLEFWLACEDFKKVKSQSKMAAKAKKIFAEFIAIQACKEVNLDSYTREHTKENLQSITRGCFDLAQKRIFGLMEKDSYPRFLRSDLYLDLINQKKMSPPL-----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P49797-1", "uniprot_id": "RGS3_RAT", "id": "P49797-1", "name": "Regulator of G protein signaling 3", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MNRFNGLCKVCSE---------------------------------RRYR-------------------------QITIRRGKDGFGFTICCDSPVRVQAVDSGGPAERAGLQQLDTVLQLNERPVEHWKCVELAHEIRSCPSEIILLVWRVVPQIKPGPDGGVLRRASCKSTHDLLSPPNKREK-NCTHGAPTRPEQRHSCHLVCDSSDGLLLGG---------WERYTEVGKRSGQHTLPALSRATTPTDPNYIILAPLNPGSQLLR---------------PVYQEDAIPEEPGTTTKGKSYTG--------LGKKSRLMKTVQTMKGHSNYQDCSALRPHIPHSSYGTYVTLAPKVLVFPVFVQPLDLCNPARTLLLSEELLLYEGRNKTSQVTLFAYSDLLLFTKEEEPGRCDVLRNPLYLQSVKLQEGSSEDLKFCVLYLAEKAECLFTLEAHSQEQKKRVCWCLSENIAKQQQLAATPT----ERKMFETEADEK-EMPLVEGKGPGAEERTPSKDPSPSQELPPGQELPPSKDPSPSQELPPGQELPPSKDPSPSQELPPGQELPSSKNPSPSQELPAGQDLPPRKESFSGQEAAPGPESPSSEDIATCQNPPQSPETSTSKDSPPGQGSSPTTEVPSCQGLPAGQE-STSQDPLLSQEPPAIPESSASDQNVLPSQESPPSQGSLSEKALAEQTISPGELPAATAGEPSASRPNFVIPEVRLDSAYSQQDGAHGGSSGEDEDAEEGEE---GEEGEEDEEDDTNDDNYGDRNEAKRSSLIETG-QGAEGGLSLRVQNSLRRRTHSEGSLLQEARGPCFASDTTLHCSDGEGTTST-WAIPSPRTLKKELGRNGGSMHHLSLFFTGHRKMSGTDLA-DDVE-ASRKRKSKNIAKDMKNKLAIFRRR-NESPGAQPAGKADKTTKSFKPTSEEALKWSESLEKLLLHKYGLEVFQAFLRTEFSEENLEFWLACEDFKKVKSQSKMAAKAKKIFAEFIAIQACKEVNLDSYTREHTKENLQSITRGCFDLAQKRIFGLMEKDSYPRFLRSDLYLDLINQKKMSPPL-----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P49796-3", "uniprot_id": "RGS3_HUMAN", "id": "P49796-3", "name": "Regulator of G protein signaling 3", "aln": "MPVIPALWEVEMGRSQGQEIETILANRSHSDSTPLPNFLSGSHRPECCTCRLLTASGAQDSLPFGRRLYSGPWRSCEEVCHVSVLSVLSTSCGLSLSLPIFPGWMEWLSPDIALPRRDEWTQTSPARKRITHAKVQGAGQLRLSIDAQDRVLLLHIIEGKGLISKQPGTCDPYVKISLIPEDSRLRHQKTQTVPDCRDPAFHEHFFFPVQEEDDQKRLLVTVWNRASQSRQSGLIGCMSFGVKSLLTPDKEISGWYYLLGEHLGRTKHLKVARRRLRPLRDPLLR----MPGGGDTENGKKLKITIPRGKDGFGFTICCDSPVRVQAVDSGGPAERAGLQQLDTVLQLNERPVEHWKCVELAHEIRSCPSEIILLVWRMVPQVKPGPDGGVLRRASCKSTHDLQSPPNKREK-NCTHGVQARPEQRHSCHLVCDSSDGLLLGG---------WERYTEVAKRGGQHTLPALSRATAPTDPNYIILAPLNPGSQLLR---------------PVYQEDTIPEESGSPSKGKSYTG--------LGKKSRLMKTVQTMKGHGNYQNCPVVRPHATHSSYGTYVTLAPKVLVFPVFVQPLDLCNPARTLLLSEELLLYEGRNKAAEVTLFAYSDLLLFTKEDEPGRCDVLRNPLYLQSVKLQEGSSEDLKFCVLYLAEKAECLFTLEAHSQEQKKRVCWCLSENIAKQQQLAASPP----DSKMFETEADEKREMALEEGKGPGAEDSPPSKEPSPGQELPPGQDLPPNKDSPSGQEPAPSQEPLSSKDSATSEGSPPGPDAPPSKDVPPCQEPPPAQDLSP------------------------------------------------------CQDLPAGQEPLPHQDPLLTKDLPAIQES--PTRDLPPCQDLPPSQVSLPAKALTEDTMSSGDLLAATGDPPAAPRPAFVIPEVRLDSTYSQKAGAEQGCSGDEEDAEEAEEVEEGEEGEEDEDEDTSDDNYGERSEAKRSSMIETG-QGAEGGLSLRVQNSLRRRTHSEGSLLQEPRGPCFASDTTLHCSDGEGAAST-WGMPSPSTLKKELGRNGGSMHHLSLFFTGHRKMSGADTVGDDDE-ASRKRKSKNLAKDMKNKLGIFRRR-NESPGAPPAGKADKMMKSFKPTSEEALKWGESLEKLLVHKYGLAVFQAFLRTEFSEENLEFWLACEDFKKVKSQSKMASKAKKIFAEYIAIQACKEVNLDSYTREHTKDNLQSVTRGCFDLAQKRIFGLMEKDSYPRFLRSDLYLDLINQKKMSPPL-----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AB32TW72-1", "uniprot_id": "A0AB32TW72_DANRE", "id": "A0AB32TW72-1", "name": "", "aln": "--------MDYSKQNSHHVTIRERRKRLYRESLWLQDPVLPKGPSTKKPCHELKRPSDSRARRSSVRHIRSVRDKRPLAASQEENVTSPAEGNWRKAVSRNSSAQVKMASVVKTTVKNDKQPATKKRRKIHPSGFRGKGQLKLIVTPGRGWLYMQVLEARGLMGREYRPCDSYVKISIAPDVDHSKRWKTRTVLDCKSPVFNEGFMLDVDEDDQKKRLLVTVWNRDRDSRRSDFLGCMSFGVHSLITSSKEIRGWYYLLGEELGRSKHLKVASRRIRQTAEAAAPNYEAGPESSGPENMQSFTVTILRGKDGFGFTICSDSPVRVQAVDPGGPAHQAGLQQLDTLLQLNGQPVEHWKCVDLAHAIRNCRNEITVVVWRTVPIMKPYYEGLIHRPSYKPSGFEFLSSTAKTQ--NKTPPLLSRPTNHKQGRRKKGSS-SDNAGSGVGESLWSWTGKREENDYKTRTQTLKG-TRVTSSNGDNYIILSPVSPGNQILQPVYSDSNGTLG-TLGRIYQTSRGLQQSPDYLQDGGLQG-QATLCRTMSSKTTTLPPSSYRQSFANYQNCTIVQSHLPHSNYGTYVSLAPKILIFPVFVQPLDLCSPERVLMLSEEMILHDSKHIALKATVFIYTDLLLLTREDEPGRCNVLQSPLYLHQIQLQDVPADKLRLYISYWIERTECLFSLEAFSSEQKRRVVQCLRDNIDKQLALRERIG----PDQMLEPKAAEQADLG---LLGFSPHSVSEPCSPSCPSASPI-----LRRTNCTSPAQRLSYPDLPDANQTSP---TSRDACKPS----------------------------------------------------------------------------------------YTDTSEIWKN---RQKEVKESDLEKREQGEGESASETISVG-------ARPTSSSSSSSPLVIPKLCLDRSFNTDALTSPSTD-----DDDDDE-------EEDEED--SDEGFLKR-----RSMVESSPCGGQQSGGLCVQRSLHRRTHSEGSLLQEPRSPRFISDQAIDCIEAKRETPERWAVPSPQTLRKELTKNGGSVHQICLLFTGRRVCGKPNCKCDMGKTAVKKKKSKNLAKDMKNRLTFLRKKTNDRHGSNPASKLDKVLKSDKPAPEEALKWAESLDTLLSHKYGLAVFRSFLQTEFSEENLDFWLACEEFKKIKSLSKMTSRAKKIFTEYISIQSCKEVNLDSYTREHIKENMENICADCFDLAQSRIFGLMERDSYPRFLRSDIYMELTNQKRPGSAADPS--", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0AB13A9N8-1", "uniprot_id": "A0AB13A9N8_DANRE", "id": "A0AB13A9N8-1", "name": "", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MQCLTVTVLRGKDGFGFTICSDSPVRIQAVDPGGPADQAGLQQLDTVLQLNGQPVKHWKCVDLAHAIRNSLSEITVVIWRTGPSVKTKFEGLIHHPSYKSSNYDTPVSPAKCKRAEKAPPLPPLPAQHRTGHRVVGQNGSEDLATGAGV---LWGERRTAVDAKTGTQTLRG-TRVKASNGENYIILSPINPGSQVLG--SGDPHRTLTGQMYPAAQTSVPLPPAASAQSAPGLASRTCFLRRSGNSKSKTQQIYQNTSNFANYQNCTIVRSHVPHANYSTYVKVTPKVLIFPIFVQPVDLCSPTRTLLITEEMILYESKHFSIKVTVFIYSDLMLVTREDEPGRCNVLQNPLYLRHLQLRDDHCKDLRFYLIHMTEKCDCLLSLEADSLEQKARVCQCLSENIQKQLRIFHGRQTFRLPQQMLEPKQDEPCDLRGRRMTSEDDHSLGSLSDASATTASSP-----QSRSLTLLEELCTSLEETCHPVPPTPPPSTEGDDGRST----------------------------------------------------------------------------------------ESSMNEIWREEECKEKETEESDFLHAQTKDCDDCDEKQVIIDEENASEVADTNAPSSSSSFIIPELRLDRSYSADALSTPGTDEEYDEDEDDEE-------EEEEED--SDDNYLERSDSKRRSMVEAGSCEKHP-GGLSVQNSLRRRTHSEGSLLQDPRTTCFTSDNAINCMEVSGAHKGGWTLPSPKTLKKELTKNGGSMHQLCMLFSGRKLSASSECSCDVGPDGTKKKKSKNLAKDMKNRLAFLRRR-NESPGSTPASKLDKTMKSVKPTPEEAMKWGESLDKLLVHKYGLAAFRAFLRTEFSEENLDFWLACEDYKKIKSQSKMTSKAKKIFAEFIAIQSCKEVNLDSYTREHTKENLQNINRSCFELAQRRIYGLMEKDSYPRFLRSELYMDLVNQKKPSTTSTSSSS", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus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identical_positions": 306, "similar_positions": 264, "identity": "23.47%" }, { "cls_id": "homologset.agr.MGI:1354735", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P98197-1", "uniprot_id": "AT11A_MOUSE", "id": "P98197-1", "name": "Phospholipid-transporting ATPase IH", "aln": "-------------------------------------------------------------------------------MDCSLLRTLVRRYCAGEENWVDSR------------------TIYVGHKEPPPGAEAYIPQRYPD--NRIVSSKYTFWNFIPKNLFEQFRRIANFYFLIIFLVQLIIDTPTS-PVTSGLPLFFVITVTAIKQGYEDWLRHKADNAMNQCPVHFIQHG--------------------------------------------------------------KLVRKQSRKLRVGDIVMVKEDETFPCDLIFLSSNRADGTCHVTTASLDGESSHKTHYAVQDT-KGFHTEADVDSLHATIECEQPQPDLYKFVGRINVYNDLN-----DPVVRPLGSENLLLRGATLKNTEKIFGVAIYTGMETKMALNYQSKSQKRSAVEKSMNTFLIVYLCILVSKALINTVLKYVWQSEPFRDEPWYNEKTESERQRNLFLRAFTDFLAFMVLFNYIIPVSMYVTVEMQKFLGSYFITWDEDMFDEEMGEGPLVNTSDLNEELGQVEYIFTDKTGTLTENNMAFKECCIEGHVYVP---------------HVICNGQVLPDSSGIDMIDSSPGVCGREREELFFRAICLCHTVQVKDDH----------------------CGDDVDGPQKSPD--AKSCV---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------YISSSPDEVALVEGVQRLGFTYLRLKDNYMEILNRE-----------NDIERFELLEVLTFDSVRRRMSVIVKS--TTGEIYLFCKGADSSIFPRVIEG---------------------------------------------------------------------------------------------------------------------------------------------------------------------KVDQVRSRVERNAVEGLRTLCVAYKRLEPEQYEDACRLLQSAKVALQDREKKLAEAYEQIEKDLVLLGATAVEDRLQEKAADTIEALQKAGIKVWVLTGDKMETASATCYACKLFRRSTQLLELTTKKLEEQSLHDVLFDLSKTVLRCSGSMTRDSFSGLSTDMHDYGLIIDGAALSLIMKPREDGSSS-GNYRELFLEICRNCSAVLCCRMAPLQKAQIVKLIKFSKEHPITLAIGDGANDVSMILEAHVGIGVIGKEGRQAARNSDYAIPKFKHLKKMLLVHGHFYYIRISELVQYFFYKNVCFIFPQFLYQFFCGFSQQTLYDTAYLTLYNISFTSLPILLYSLMEQHVGIDVLKRDPTLYRDIAKNALLRWRVFIYWTFLGVFDALVFFFGAYFIFENTTVTINGQ--------MFGNWTFGTLVFTVMVLTVTLK-LALDTHYWTWINHFVIWGSLLFYIAFSLLWGGVIWPFLSYQRMYYVFISMLSSGPAWLGIILLVTVGLLPDVLKKVLCRQLWPTATERTQNIQ---------------HQDSISEFTPLASLPSWGAQGSR---------LLAAQCSSPSGRVVCSRWESE-ECPVLPLHPGLPHKARYGCCRSSLEMPT----------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D4A7K5-1", "uniprot_id": "D4A7K5_RAT", "id": "D4A7K5-1", "name": "Phospholipid-transporting ATPase", "aln": "-------------------------------------------------------------------------------MDCSLLRTLVRRYCAGEENWVDSR------------------TIYVGHKEPPPGAEAYIPQRYPD--NRIVSSKYTFWNFIPKNLFEQFRRIANFYFLIIFLVQLIIDTPTS-PVTSGLPLFFVITVTAIKQGYEDWLRHKADSAMNQCPVHFIQHG--------------------------------------------------------------KLVRKQSRKLRVGDIVMVKEDETFPCDLIFLSSNRADGTCHVTTASLDGESSHKTHYAVQDT-KGFHTEADVDSLHATIECEQPQPDLYKFVGRINVYNDLN-----DPVVRPLGSENLLLRGATLKNTEKIFGVAIYTGMETKMALNYQSKSQKRSAVEKSMNTFLIVYLCILVSKALINTVLKYVWQSEPFRDEPWYNQKTESERQRNLFLRAFTDFLAFMVLFNYIIPVSMYVTVEMQKFLGSYFITWDEDMFDEEMGEGPLVNTSDLNEELGQVEYIFTDKTGTLTENNMAFKECCIEGHVYVP---------------HVICNGQVLPDSSGIDMIDSSPGVSGREREELFFRAICLCHTVQVKDDH----------------------CGDDVDGPQKSPD--AKSCV---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------YISSSPDEVALVEGMQRLGFTYLRLKDNYMEILNRE-----------NDIERFELLEVLTFDSVRRRMSVIVKS--TTGEIYLFCKGADSSIFPRVIEG---------------------------------------------------------------------------------------------------------------------------------------------------------------------KVDQVRSRVERNAVEGLRTLCVAYKRLEPEQYEDACRLLQDAKVALQDREKKLAEAYEQIEKDLILLGATAVEDRLQEKAADTIEALQKAGIKVWVLTGDKMETASATCYACKLFRRSTQLLELTTKKLEEQSLHDVLFELSKTVLRCSGSLTRDSFSGLSTDMHDYGLIIDGAALSLIMKPREDGSSS-GNYRELFLEICRNCSAVLCCRMAPLQKAQIVKLIKFSKEHPITLAIGDGANDVSMILEAHVGIGVIGKEGRQAARNSDYAIPKFKHLKKMLLVHGHFYYIRISELVQYFFYKNVCFIFPQFLYQFFCGFSQQTLYDTAYLTLYNISFTSLPILLYSLMEQHVGIDVLKRDPSLYRDIAKNALLRWRLFIYWTFLGVFDALVFFFGAYFMFENTTVTINGQ--------MFGNWTFGTLVFTVMVFTVTLK-LALDTHYWTWINHFVIWGSLLFYIVFSLLWGGIIWPFLSYQRMYYVFIYMLSSGPAWLGIILLVTVGLLPDVLKKVLCRQLWPTATERTQTVQ---------------LRDSISEFTPLASLQSRGAQGTR---------LLAAQCSSPSGRVVCSRWESE-EYPVLPTHPGLLHKARYGCCRSSLETPT----------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P98196-1", "uniprot_id": "AT11A_HUMAN", "id": "P98196-1", "name": "Phospholipid-transporting ATPase IH", "aln": "-------------------------------------------------------------------------------MDCSLVRTLVHRYCAGEENWVDSR------------------TIYVGHREPPPGAEAYIPQRYPD--NRIVSSKYTFWNFIPKNLFEQFRRVANFYFLIIFLVQLIIDTPTS-PVTSGLPLFFVITVTAIKQGYEDWLRHKADNAMNQCPVHFIQHG--------------------------------------------------------------KLVRKQSRKLRVGDIVMVKEDETFPCDLIFLSSNRGDGTCHVTTASLDGESSHKTHYAVQDT-KGFHTEEDIGGLHATIECEQPQPDLYKFVGRINVYSDLN-----DPVVRPLGSENLLLRGATLKNTEKIFGVAIYTGMETKMALNYQSKSQKRSAVEKSMNAFLIVYLCILISKALINTVLKYMWQSEPFRDEPWYNQKTESERQRNLFLKAFTDFLAFMVLFNYIIPVSMYVTVEMQKFLGSYFITWDEDMFDEETGEGPLVNTSDLNEELGQVEYIFTDKTGTLTENNMEFKECCIEGHVYVP---------------HVICNGQVLPESSGIDMIDSSPSVNGREREELFFRALCLCHTVQVKDD-------------------------DSVDGPRKSPDG-GKSCV---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------YISSSPDEVALVEGVQRLGFTYLRLKDNYMEILNRE-----------NHIERFELLEILSFDSVRRRMSVIVKS--ATGEIYLFCKGADSSIFPRVIEG---------------------------------------------------------------------------------------------------------------------------------------------------------------------KVDQIRARVERNAVEGLRTLCVAYKRLIQEEYEGICKLLQAAKVALQDREKKLAEAYEQIEKDLTLLGATAVEDRLQEKAADTIEALQKAGIKVWVLTGDKMETAAATCYACKLFRRNTQLLELTTKRIEEQSLHDVLFELSKTVLRHSGSLTRDNLSGLSADMQDYGLIIDGAALSLIMKPREDGSS--GNYRELFLEICRSCSAVLCCRMAPLQKAQIVKLIKFSKEHPITLAIGDGANDVSMILEAHVGIGVIGKEGRQAARNSDYAIPKFKHLKKMLLVHGHFYYIRISELVQYFFYKNVCFIFPQFLYQFFCGFSQQTLYDTAYLTLYNISFTSLPILLYSLMEQHVGIDVLKRDPTLYRDVAKNALLRWRVFIYWTLLGLFDALVFFFGAYFVFENTTVTSNGQ--------IFGNWTFGTLVFTVMVFTVTLK-LALDTHYWTWINHFVIWGSLLFYVVFSLLWGGVIWPFLNYQRMYYVFIQMLSSGPAWLAIVLLVTISLLPDVLKKVLCRQLWPTATERVQTKS---------------QCLSV-------------EQSTI---------FMLSQTSS------------------------------------SLSF------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9Q0D3-1", "uniprot_id": "A0A8M9Q0D3_DANRE", "id": "A0A8M9Q0D3-1", "name": "Phospholipid-transporting ATPase", "aln": "-------------------------------------------------------------------------------MDFSTIRNLITRYCTGEENWVDSR------------------TVYIGHKEPPPGTEAYIPQRFPD--NRIVSSKYTFWNFIPKNLFEQFRRIANFYFLIIFLVQLIIDTPTS-PMTSGLPLFFVITVTAIKQGYEDWIRHKADNSVNQCPVHIVQHG--------------------------------------------------------------KVVRKQSQKLRVGDIVQVKENETFPCDLILLSTSREDGTCFVTTASLDGESSHKTYYAVQDT-KAFSTAEEVDTLHATIECEQPQPDLYKFVGRINIYLDRD-----EPIARPLGSENLLLRGATLKNTEYIHAVAIYTGMETKMALNYQSKSQKRSAVEKSMNAYLIVYLCILISKALINTVLKYVWQADPNRDEPWYNQRTESERQRHVLIRAFTDFLAFMVLFNYIIPVSMYVTVEMQKFLGSYFILWDDDMFDEEVGERPLVNTSDLNEELGQVEYVFTDKTGTLTENNMELRECCVDGHVYVP---------------HAICNGQILPGAAGMDMIDSSPGVEGKEREELFFRALCLCHTVQVKEE-------------------------ETVDGIKRGIHQGKATSF---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------YISSSPDEVALVEGMKRLGFTYLRLKDSHMEILNRE-----------DEMERFELLDVLNFDSVRRRMSVIVRS--NSGEYYLFCKGADSSVFPRVVSG---------------------------------------------------------------------------------------------------------------------------------------------------------------------KVEQVRARVEHNAVEGLRTLCVAYKRLSQEEYEETCRLLTSAKLALQERDKKLAEAYDVIEKDFILLGATAVEDRLQDKAADTIESLHKAGIKVWVLTGDKMETAAATCYASKLFHRNTQILELTTKRTEEQSLHDVLFDLSRTVLRQHGSMTRDTFSGLSGDYQDYGLIIDGATLSAVLKPTQDATSNSGNYKEIFLEICRNCSAVLCCRMAPLQKAQIVKLIKASKEHPITLAIGDGANDVSMILEAHVGIGIMGKEGRQAARNSDYAITKFKHLKKMLLVHGHYYYIRIAELVQYFFYKNVCFIFPQFLYQFFCGFSQQPLYDTAYLTLYNISFTSLPILLYSLMEQHINMDILKRDPSLYRDIAKNSLLTWPTFIYWTFLGVFDAVVFFFGAFFLFDNTTFTSNGQLMATNTQMMFGNWTFGTLVFTVLVFTVTLK-LALDTHYWTWINHFVIWGSLLFYVIFSLLWGGIIWPFLNYQRMYYVFMQMLSSGPAWLSIILLIIVSLLPDVLKKVLCRALWPTTTERIQNADKL-------------YKGHLSEFSPLTSLHAPPARKHERRGNERQNHAHRRSDSSPTKKLMCTYWGGKPDYCTFSSFLRIGENPRFSGAAYAYSAPGPETSV-----------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VXG7-1", "uniprot_id": "Q9VXG7_DROME", "id": "Q9VXG7-1", "name": "Phospholipid-transporting ATPase", "aln": "------------------------------------------------------------------------------------------MGADKKK--------------------------SADPLRIQIGG---IESRQQKPLNRVTTTKYTWFTFLPLNFYEQFRRAVYFYFLIITIVSFFVNETIS-PLVSLLPLLFVMIITALKEGLEDYSRSKSDKLVNTARVTVIRNG--------------------------------------------------------------KEEIINSQFIVPGDLVVVRNDGDVPCDLVLLQSSSADRKCFVNTANLDGETNLKTICVPTNY-LLAGDHELQG--KDCIVCEPSSADLYTFNGRLELRSGNDGAGSSAGDALPLTIDNLLLRGVRVKSTERVVGCAIYTGMHTKLQLNSRYTGNKSASSEKYINRFMVALIVGMIVVVVVLYLIERHKEAKIVPTMPYQGPPTNFNS----AWQIFEDFLSFLLLFNYMVPISAYMNIEVYRIFGMHFMHNDLHLYDEETDQPCRVNASNLNEELGQVNILFSDKTGTLTKNLMKFVNCYVPGTNYQL---------------QNTH----LVSEGTDEKFELEKLDAD---AAVLFEALAVCHTVEVLQ-------------------EVGDKTLESSESVSEQSHLMSRN------------------------------------------------IVDR-------------------------------------------------------------------------------------------------------------------------------------------YQASSPDEKALLEGCASLGLVYEGQENDVLSICRYP----------SAEKVQFKRLHVLEFSSERQRMSVIVRD--QSDTIWLYSKGAESAIFPRCKAS--------------------------------------------------------------------------------------------------------------------------------------------------------------------PLVEQTDAQITKYAQNGLRTMAVGRRMLTDDELFHFEELYRKANTQLSNRNELIASCYETVENELDLLGATALEDALQEHVGETLEALQAAGLKIWVLTGDKVETAYNIGLACRHIPRGSKQHFIINTTEPAE------------LLARLD------MIGDD---EPEVLIVDGTTITALLEHTP----------RQFADLALRCRAVLCCRLSPLQKSEIVTLIKR-RKKYITAAIGDGANDVSMIQEAHIGIGITGREGKQAARCADFSIARFEMLRRLFLVHGHYNSQRLAFLVLFYCYKNIIITGCMALYQVYDLYSATNVYNSIYLWLFDIVYISFSFTVLAICDKDYSEETLLSHPELYKPLAHNRQASMGVFSLWILNGFVQCFIIFFFTYAMLNDANVLFNGG-------QTASFQTFGTMLITIIVIVGNLK-LLLVAHYMTYRNFAMILASIAAFMLTTYLY-----NLYTSGELYDVYNQFLSSLPIWLFTIICSVACLLPDFVIKVVN------------DMY----------------------------------RKVP----------LKSKPVV----------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VXG6-1", "uniprot_id": "Q9VXG6_DROME", "id": "Q9VXG6-1", "name": "Phospholipid-transporting ATPase", "aln": "-------------------------------------------------------------------------MNFFGHDHLSGFRRIDRLGAHRQTPWADQESFHLKDAFLWNWHKGSRVSTINDWLQIQIGGPQDIKKKRPKGQNRIKSTKYTLITFLPQNLLEQFRRIANFYFLVMTIISLLIDSPVS-PMTSLLPLVFVIAVTAAKQGYEDILRYRTDNVVNSSPVTVIRDG--------------------------------------------------------------KEAIIKSQDVIPGELIVVERDCDVPCDLVLLRSTDPHGKCFITTANLDGESNLKTLMVPRDL-PTVDLPEMHK--LGIIECESPTTDLYSFNGKIELKGGE-------GRVLPLSTENVLLRGSRVKNTECVIGCAVYTGMISKLQLNSRLTRNKNASSETYINRFLIVILVALIAIVTLLYFLKRYNELFVIPKLTYLGDATDSYS----VKQFLQDYLSFLILFNYLIPISLYVTIELQRVIGSWFMEWDLELYENETDQPCVVNTSNLNEELGQINILFSDKTGTLTKNEMNFQQCSINGNKFLF---------------KKTR----LEDEETKALLDINKFSAN---QRVFFQALSICHTVQVASGSLEQADAGTAKREPVTAIKSGPPEMYSISDITEESHNASQQSELNVGHTIDNSVSAHPNGVNSTIISSDVNPLLVSDDGYGVERRKRPVVIKRSPNFARSNRMNNGAASDLNINQTDPNTVTNGVEPTTNFRPISLQFRRSTSEKDLQQSWEAPSGQAPGHRRAHSYGAPNAYLTNPVTASTPPAGVLFRSPSTTSRESYAAPTFTRQPTILVRAESQRRKNEIRDFIFTLDYQASSPDEKALVEACANLGMVYTGDDDETLRVRIVPPHMDYKRPFAKPREETFQRLHVLEFTSDRKRMSVIVRD--TDGKKWIYTKGAESYVFPLCANSSA------------------------------------------------------------------------------------------------------------------------------------------------------------------ELVTKTDAHISDFARLGLRTLAIARRLISEEEYQDFLVELAQANSSLENRKQLSEECYAKIESNLDLLGATAVEDALQDDVADTLVSLQAAGIKIWVLTGDKVETALNIALSCGHIPPDAKKYFIMECKNREE------------MLLHLNALDREIIFGIG---QECALLIDGKSLGVALAEAS----------SEFRDVAVKCTAVLCCRLSPLQKSEVVSLIKSSNENYNTASIGDGANDVSMIQEAHVGIGIMGREGRQAARCADFAFAKFCMLKRLLLVHGHYHSVRLSLLVLYFFYKNIVFMGIMFLFQFHTLFSSSSVYDSLFLTLYNVIYTSLPILFIAISEKPYTEEKLMRTPQLYKKNTDNKQLHWPYFLMWVLFAIYHSVIIFYFAFCFFYYNNVLLNYG-------QTVAFSCFGTLLMWTVVVVVNLK-LWLESMYLSFWYIFTIIISILGFVVTTVIYN--VINLDYDTDIYWAYNNLLASLPVWLWIIVTCVACLVPDYTIRMLQRALNIKSFSIFPGKQ----------------------------------RKLK----------MREKFESTYL-------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q12674-1", "uniprot_id": "ATC8_YEAST", "id": "Q12674-1", "name": "Probable phospholipid-transporting ATPase DNF3", "aln": "MGIADGQRRRSSSLRTQMFNKHLYDKYRGRTDDEIELEDINESKTFSGSDNNDKDDRDETSGNYAAEEDYEMEEYGSPDVSYSIITKILDTILDRRRTFHSKDGRHIPIILDHN------AIEYKQAATKRDGHLIDERFNKPYCDNRITSSRYTFYSFLPRQLYAQFSKLANTYFFIVAVLQMIPGWSTTGTYTTIIPLCVFMGISMTREAWDDFRRHRLDKEENNKPVGVLVKDGNNDAQEVYTLPSSVVSSTAYLTKSAAAENNPPLNDDRNSSQGHFLDTHFNNFELLKNKYNVHIHQKKWEKLRVGDFVLLTQDDWVPADLLLLTCDGENSECFVETMALDGETNLKSKQPHPELNKLTKAASGLANINAQVTVEDPNIDLYNFEGNLELKNHRN----DTIMKYPLGPDNVIYRGSILRNTQNVVGMVIFSGEETKIRMNALKNPRTKAPKLQRKINMIIVFMVFVVATISLFSYLGHVLHKKKYIDQNKAWYLFQADAG------VAPTIMSFIIMYNTVIPLSLYVTMEIIKVVQSKMMEWDIDMYHAETNTPCESRTATILEELGQVSYIFSDKTGTLTDNKMIFRKFSLCGSSWLHNVDLGNSEDNFEDNRDNTNSLRLPPKAHNGSSIDVVSIGDQNVLDRLGFSDAPIEKGHRPSLDNFPKSRNSIEYKGNSSAIYTGRPSMRSLFGKDNSHLSKQASVISPSETFSENIKSSFDLIQFIQRYPTALFSQKAKFFFLSLALCHSCLPKKTHN--------------------------------------------------------------------------------------------------------------------------------ESIGEDSIEYQSSSPDELALVTAARDLGYIVLNRNAQILTIKTFPDGFDG-----EAKLENYEILNYIDFNSQRKRMSVLVRMPNQPNQVLLICKGADNVIMERLHDRELAAKKMADICTSTKERKDAEAELVLQQRKSLERMVDEEAMARTSLRNSLSSVPRASLSLQAVRKSLSMKNSRTRDPEKQIDSIDQFLETVKKSDQEIGSVVNKSRKSLHKQQIEKYGPRISIDGTHFPNNNVPIDTRKEGLQHDYDTEILEHIGSDELILNEEYVIERTLQAIDEFSTEGLRTLVYAYKWIDIGQYENWNKRYHQAKTSLTDRKIKVDEAGAEIEDGLNLLGVTAIEDKLQDGVSEAIEKIRRAGIKMWMLTGDKRETAINIGYSCMLIKDYSTVVILTTTD-----------------ENIISKMNAVSQEVDSGNIAHCVVVIDGATMAMFEGNPT--------YMSVFVELCTKTDSVICCRASPSQKALMVSNIRNTDPNLVTLAIGDGANDIAMIQSADIGVGIAGKEGLQASRVSDYSIGQFRFLLKLLFVHGRYNYIRTSKFMLCTFYKEITFYFTQLIYQRYTMFSGSSLYEPWSLSMFNTLFTSLPVLCIGMFEKDLKPMTLLTVPELYSYGRLSQGFNWLIFMEWVILATTNSLIITFLNVVMWGMSSLS------------DNTMYPLGLINFTAIVALINVKSQFVEMHNRNWLAFTSVVLSCGGWLVWCCALPILNNTDQIYDVAYGFYNHFGKDITFWCTSLVLALLPITLDIVYKTFKVMIWPSDSDIFAELEQKSDIRKKLELGAYSEMRQGWTWDKDPSTFTRYTDKVLSRPRTNSRASAKTHNSSIYSMSNGNVDHSSKKNFFGNSSKKSSERYEVLPSGKLIKRPSLKTQSSKDSIGGNITTKLTKKLKLPSRNVEDEDVNQIIQARLKDLE", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . * . **: :::** .*:* :: ** : . **::: ::.:: . . : . .: :** ..: :: ::. :* * : *. * * .: .. : : . : *::: : .: .*.**::* . *.: * ****:. *: : : * . ***.* *.::: ** :*:: ** ::.*: : . .:::* :*: :* . .. :. ::. : :: : : . : ::*::::* ::*:* *:.:*: :.. :: * .::. * . .:: : *****:. :*:*******.* * : : : * : . :: : * : : . . . * :***** **: . ** . . : : :: *. : * * *:****:*: . : ***:. :: : : : : ****: . : : : *: * :*. .. :*. : ***.**:** **: ..::: :: **:*:*:***** *** :. : : : . . :::** :: * ::. :*:*** :* **: :*. *: : * :*******::** .*.:*:*: *:** **:* :*::: :* * ::::***:: * : :: **:: : ::* . :* :*:. * ::: : *:.. .: :: * * ** . * * : . ...:: : . .. :* : : :* .:* : .: : * :: * : : . . * :: : * : . ", "identical_positions": 179, "similar_positions": 297, "identity": "9.72%" }, { "cls_id": "homologset.agr.MGI:1354736", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P59997-1", "uniprot_id": "KDM2A_MOUSE", "id": "P59997-1", "name": "Lysine-specific demethylase 2A", "aln": "---------------------------------------------------------MEPEEERIRYSQR-----------LRGTMRRR------YEDDGISDDEIEGKRTFDLEEKLQTNKYNAN-FVTFMEGKDFNVEYIQ--------------------RGGLRDPLIFKNSDGLGIKMPDP-----DFTVNDVKMCVGSRRMVDVMDVNTQKGIEMTMAQWTRYY-ETPEEEREKLYNVISLEFSHTRLENMVQWPSTVDFIDWVDNMWPRHLKESQTESTNAILEMQYPKVQKYCLISVRGCYTDFHVDFGGTSVWYHIHQGGKVFWLIPPTAHNLELYENWLLSGKQGDIFLGDRVSDCQRIELKQGYTFVIPSGWIHAVYTPTDTLVFGGNFLHSFNIPMQLKIYSIEDRTRVPNKFRYPFYYEMCWYVLERYVYCITNRSHLTKDFQKESLSMDMELN---ELESGNGDEEGVDREARRMNNKRSVLTSPVANGVNLDYDGLGKACRSLPSLKKTLSGDSSSDSTRGSHNGQVWDPQCSPKKDRQVHLTHFELEGLR-------CLVDKLESLPLHKKCVPTGIEDEDALIADVKILLEELASSDPKLALTG---VPIVQWPKRDKLKFPTRPKVRVPTIPITKPHTMKPAPRLTPVR-PAAASPI-------------------------------------------------------------VSGARRRRVRCRKCKACVQGECGVCHYCRDMKKFGGPGRMKQSCVLRQCLAPRLPHSVTCSLCGEV----------DQNEETQDFEKKLMECCICNEIVHPGCLQMDGE---------GLLNEELPNCWECPKCYQEDSSDKAQKRKIE-----------------------------------------ESDEEAVQAKVLRPLRSCEEPLTPPPHSPTSMLQLIHDPVS---------------------------PRGMVTRSSPGAGPSDHHSASRDERFKRRQLLR-------LQATERTMVREK---------------------ENNPSGKKELSEVEKAKIRG-----------------------------------------------------------------------------------SYLTVTLQRPTKELHG-TSIVPKLQAITAS------------------------------------SANLRPNPRVLMQHCPARNPQHGDEEGLGGEEEEEEEEEE-DDSAEEGGAARLNGRGSWAQDGDESWMQREVWMSVFRYLSRKELCECMRVCKTWYKWCCDKRLWTKIDLSRCKAIVPQALSGIIKRQPVSLDLSWTNISKKQLTWLVNRLPGLKDLLLAGCSWSAVSALSTSSCPLLRTLDLRWAVGIKDPQIRDLLTPPTDK--PGQDNRSKLRNMTDFRLAGLDITDATLRLIIRHMPLLSRLDLSHCSHLTDQSSNLLTAVGSSTRYSLTELNMAGCNKLTDQTLFFLRRIANVTLIDLRGCKQITRKACEHFISDLSINSLYCLSDEKLIQKIS-------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8I6ARD6-1", "uniprot_id": "A0A8I6ARD6_RAT", "id": "A0A8I6ARD6-1", "name": "[histone H3]-dimethyl-L-lysine(36) demethylase", "aln": "----------------------------------------------------------------VGREEG-----------KRGTMRRR------YEDDGISDDEIEGKRTFDLEEKLHTNKYNAN-FVTFMEGKDFNVEYIQ--------------------RGGLRDPLIFKNSDGLGIKMPDP-----DFTVNDVKMCVGSRRMVDVMDVNTQKGIEMTMAQWTRYY-ETPEEEREKLYNVISLEFSHTRLENMVQRPSTVDFIDWVDNMWPRHLKESQTESTNAILEMQYPKVQKYCLMSVRGCYTDFHVDFGGTSVWYHIHQGGKVFWLIPPTAHNLELYENWLLSGKQGDIFLGDRVSDCQRIELKQGYTFVIPSGWIHAVYTPTDTLVFGGNFLHSFNIPMQLKIYSIEDRTRVPNKFRYPFYYEMCWYVLERYVYCITNRSHLTKEFQKESLSMDMELN---ELESGNGDEEGADKEARRMNSKRSVLTSPVANGVNLDYDGLGKACRSLPNLKKTLSGDSSSDSSRGSHNGQVWDPQCSPRKDRQVHLTHFELEGLR-------CLVDKLESLPLHKKCVPTGIEDEDALIADVKILLEELASSDPKLALTG---VPIVQWPKRDKLKFPTRPKVRVPTIPITKPHTMKPAPRLTPVR-PAAASPI-------------------------------------------------------------VSGARRRRVRCRKCKACVQGECGVCHYCRDMKKFGGPGRMKQSCVLRQCLAPRLPHSVTCSLCGEV----------DQNEETQDFEKKLMECCICNEIVHPGCLQMDGE---------GLLNEELPNCWECPKCYQEDSSEKAQKRKIE-----------------------------------------ESDEEAVQAKVLRPLRSCEEPLTPPPHSPTSMLQLIHDPVS---------------------------PRGMVTRSSPGAGPSDHHSASRDERFKRRQLLR-------LQATERTMVREK---------------------ENNPSGKKELSEVEKAKIRG-----------------------------------------------------------------------------------SYLTVTLQRPTKELHG-TSIVPKLQAITAS------------------------------------SANLRPNPRVLMQHCPARNPQRGDEEGLGGEEEEEEEEEE-DDSAEEGGAARLNGRGSWAQDGDESWMQREVWMSVFRYLSRRELCECMRVCKTWYKWCCDKRLWTKIDLSRCKAIVPQALSGIIKRQPVSLDLSWTNISKKQLTWLVNRLPGLKDLLLAGCSWSAVSALSTSSCPLLRTLDLRWAVGIKDPQIRDLLTPPTDK--PGQDNRSKLRNMTDFRLAGLDITDATLRLIIRHMPLLSRLDLSHCSHLTDQSSNLLTAVGSSTRYSLTELNMAGCNKLTDQTLFFLRRIANVTLIDLRGCKQITRKACEHFISDLSINSLYCLSDEKLIQKIS-------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9Y2K7-1", "uniprot_id": "KDM2A_HUMAN", "id": "Q9Y2K7-1", "name": "Lysine-specific demethylase 2A", "aln": "---------------------------------------------------------MEPEEERIRYSQR-----------LRGTMRRR------YEDDGISDDEIEGKRTFDLEEKLHTNKYNAN-FVTFMEGKDFNVEYIQ--------------------RGGLRDPLIFKNSDGLGIKMPDP-----DFTVNDVKMCVGSRRMVDVMDVNTQKGIEMTMAQWTRYY-ETPEEEREKLYNVISLEFSHTRLENMVQRPSTVDFIDWVDNMWPRHLKESQTESTNAILEMQYPKVQKYCLMSVRGCYTDFHVDFGGTSVWYHIHQGGKVFWLIPPTAHNLELYENWLLSGKQGDIFLGDRVSDCQRIELKQGYTFVIPSGWIHAVYTPTDTLVFGGNFLHSFNIPMQLKIYNIEDRTRVPNKFRYPFYYEMCWYVLERYVYCITNRSHLTKEFQKESLSMDLELN---GLESGNGDEEAVDREPRRLSSRRSVLTSPVANGVNLDYDGLGKTCRSLPSLKKTLAGDSSSDCSRGSHNGQVWDPQCAPRKDRQVHLTHFELEGLR-------CLVDKLESLPLHKKCVPTGIEDEDALIADVKILLEELANSDPKLALTG---VPIVQWPKRDKLKFPTRPKVRVPTIPITKPHTMKPAPRLTPVR-PAAASPI-------------------------------------------------------------VSGARRRRVRCRKCKACVQGECGVCHYCRDMKKFGGPGRMKQSCVLRQCLAPRLPHSVTCSLCGEV----------DQNEETQDFEKKLMECCICNEIVHPGCLQMDGE---------GLLNEELPNCWECPKCYQEDSSEKAQKRKME-----------------------------------------ESDEEAVQAKVLRPLRSCDEPLTPPPHSPTSMLQLIHDPVS---------------------------PRGMVTRSSPGAGPSDHHSASRDERFKRRQLLR-------LQATERTMVREK---------------------ENNPSGKKELSEVEKAKIRG-----------------------------------------------------------------------------------SYLTVTLQRPTKELHG-TSIVPKLQAITAS------------------------------------SANLRHSPRVLVQHCPARTPQRGDEEGLGGEEEEEEEEEEEDDSAEEGGAARLNGRGSWAQDGDESWMQREVWMSVFRYLSRRELCECMRVCKTWYKWCCDKRLWTKIDLSRCKAIVPQALSGIIKRQPVSLDLSWTNISKKQLTWLVNRLPGLKDLLLAGCSWSAVSALSTSSCPLLRTLDLRWAVGIKDPQIRDLLTPPADK--PGQDNRSKLRNMTDFRLAGLDITDATLRLIIRHMPLLSRLDLSHCSHLTDQSSNLLTAVGSSTRYSLTELNMAGCNKLTDQTLIYLRRIANVTLIDLRGCKQITRKACEHFISDLSINSLYCLSDEKLIQKIS-------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1PZC6-1", "uniprot_id": "A0A8M1PZC6_DANRE", "id": "A0A8M1PZC6-1", "name": "[histone H3]-dimethyl-L-lysine(36) demethylase", "aln": "-----------------------------------------------------------MSEAKSRYSKR-----------LRSGTRRR------YQDDGISDDEIEGKRSFDLEEKLQSDRYNSN-LVKIMDGKDFTLEYIQ--------------------REGLRDPIIFKKADGLGIKMPDP-----DFSVSDVKLFVGSRRMIDVMDAATQKGIEMSMGQWRRYY-ETPASQREKLYNVISLEFSHTKLEHLVKRPTSVDMIDWVDNMWPRHLKERQRDSTNAITDMQYPKVQKYCLMSVEGCFTDFHIDFGGTSVWYHIHKGGKVFWLIPPTPQNLELYENWVLSAKQGDIFLGDKASMCQRIELKQGYTFMIPSGWIHAVYTPMDTLVFGGNFLHSFNIPMQLNIFNIEDRTRVPSKFRYPFYFEMCWYVLERYLYCLTNTSHLTPEFQKHSLGIGLKKEDVIKPAKPDGDSESEDEEVVKEEPEEEAVTPPARPGV-------------------------------------------------KVHLAPFELEGLW-------ALLHKLEDLPAHKKCVPAGIRNAPALLSDIRKLLEEHANDNPKLSYTG---KPIVKWPKRPSWYQPPPP---PPPSHLYRPRAPGSGPMLAPVPRPVKPSSS-------------------------------------------------------------ISALRRRRVRCKRCEACLRTECGNCNYCRDMRKFGGPGRLKKSCVLRQCLAPALPLTAVCVICKEG----------NQESDDTESVQMLMECSECAQITHPECIKVPGE---------GVINKDLPSCWECPKCVQGKKTESSSSSEEE-----------------------TDSSVSN-SSRLSGPPAKRAYREGIGVEGLRIARRGRSSISPSSLPITRSRRQPPPSQRLLLQHQQNRKRAGALELQLRKR--IKLERNKILQSTRSPVSLSPKLLRQRSLE-RRGLIRAGPGQSLSRGRGSSSFRGRGLRVRGGGRGGGLRERMEMAVEREDSAEEEQQERKENGQYNGKENRPQRLSGKAGEDENGDAHRNGESEESSE----------------GGEP------TLSDTS--------AALTDDVRGQESCVTVKLQ-PSRAKRDPSTIVPKLEANLSSRSLPPSHKALLRPPLRNGARCSDAPHSPADRLHVNKSHALSSSSHTLTRRASKNSNLRSNFEDSTHRLTRERIQKNARSERAKSSD-SCPSSTFHSGGGNEPGWEKEVWVSVFRYLTRAELCVCMAVCKSWYKWGCDKRLWTRISLSRSRSMSPQVLTGIIKRQPVTLDLSWANITKKQLSWLINRLPGLKDLVLSGCNWSSVSALSSPSCPLLRSLDLSWADGIKDAQIRELLNP------PGSDNRSQMKNMQCLWLCGLEVTEATLRLIIRHMPLLTRLELSRCP-ITDGALNLLSAVGSSTRNTLTHLNLAGCTQLTDRCLVYLRRLSCLSILDLRDCKGVSVQACQSFISELSVNTLYYLSDDKLIERIS-------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8M2B724-1", "uniprot_id": "A0A8M2B724_DANRE", "id": "A0A8M2B724-1", "name": "[histone H3]-dimethyl-L-lysine(36) demethylase", "aln": "---------------------------------------------MENGQEVLTLVDGGMLLMRRRGRKRKSQQGDEDVTLKRSGTRRR------YQDDGISDDEIDGRRTFDLEEKLHSSFFSSD-RVKRMEGKDFSYEYVQ--------------------RHGLRDPIIFEKPEGLGIKMPDP-----DFTVNDVKLFVGSRRIVDVMDVATQKGTEMSMAQWRRYY-ETPPSQREKLYNVISLEFSHTKLETLVKRPSTVDMIDWVDNMWPRHLKERQRDSTNSIMEMQYPKVQKYCLMSVQGCYTDFHIDFGGTSVWYHIHKGCKVFWLIPPTPQNLELYENWVLSGKQGDIFLGDRATDCQRIELKQGYTFIIPSGWIHAVYTPVDTLVFGGNFLHSFNVPMQLDISGIEDRTRVPVKFRYPFFFEMCWYVLERYLYSLTNKSHLIPEFQKHSLGIGLKRE----------NSEVLNGHAKEERDEMDAPSPPSAPGL-------------------------------------------------KTHLTAFELEGLW-------RLVGKLESLPSNKKCVPSGIHNAAALLLDIRALLKEHANDIPKLSYTG---RPIVRWPKRPPWYQPPPP---PPP--VMRPKLATT----PIVPRPVKPASN-------------------------------------------------------------MSVLRRRRVRCKRCEACLRTECGDCNFCRDMKKFGGPGKLKQTCVLRQCLAPGLPLSAVCELCGEG----------NQETS-----EELMECSNCAQIAHPSCLKTSGE---------GVVNKDLPSCWECPKCVLGKDTDSESSGSGDDITAQDGSGGRGGEGGAWHGVGRPPSSLSHGSLQKRAAAPEQRLRKRIKLDGGKSHKRKSSSLDPRVAKIYRRHGMEHDDDSGSDDDGDGGRMSSVRSSVSSSRRGYGASRRGVWRGSSQRGPRGGGSLSSSSLKMRRGLGARGERGGRVRLRGGSQMRRRRYETDDDDDDDDDDDDDDDDDDDEDEDDEDDSEEDRHVSRSEKEHRSRRRR-RRGDDYDDDEDEDDDDEEDSEEQDYEGEDDEMEDLDDGGDEDDEDGENQSDSDPDPPVLLVSDLNDDLLN-DSYLTVTLHRPPKAKRDPGSIVPKLEAAMSPRTGG-SSGFMQRKTLPK-ARPKTSSSTPAG------NGLSQAKSGRPTRRSSNQDGRERDTASPSSMSSRSSVSPPPPPPAVTSSSPSLLSHPSFRDAGNELGCEKDIWVSVFRYLDRTDLAVCMRVCKAWFKWCCDKRLWTRIDLSRCRALSPQAVTAIIKLQPVTLDLSWTPVSKKQLAWLIHHLPSLKDLIMSGCSSLCVSALSSPSCPSLRTLDLCWAVGVKDSQIKDLIVQ------PGSESRSRLRSLVSLRLSGLELSDAVIKTMVRHMPSLRQLDLSYCQGLTDQSINLLTATGCNTRNTLRQLNLSGCNKLSDGCLSYMKRLSALALLDLRGCKNVTRHGCENFISDLSYCTVFCLTEDKLIQRVS-------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VHH9-1", "uniprot_id": "JHD1_DROME", "id": "Q9VHH9-1", "name": "JmjC domain-containing histone demethylation protein 1", "aln": "------------------------------------------MSTAVETGSSPAKSNSNNSSSGGNNNNGNGNLSPNAKGVQRRQLRERKQRKLYLEEWSLGDEDGEGTRGFSVAEKLESSKFAQAGMVREMRGCDLTVAFLQ--------------------QHGFNIPLLFRDKAGLGLRMPDPQ----EFTVNDVRLCVGSRRLLDVMDVNTQKNLQMTMKEWQQYY-DSP--QKDRLLNVISLEFSHTRLDRFVQSPEIVRQIDWVDVVWPKQLKDAQREGTNLLGGMMYPKVQKYCLMSVKNCYTDFHIDFGGTSVWYHILRGSKVFWLIPPTDRNLQLYEKWVLSGKQADIFFGDTVEKCARVYLTAGNTFFIPTGWIHAVYTPTQSLVFGGNFLHSFGIVKQLKTASVEDSTKVPQKFRYPFFTEMLWYVLARYVHTLLGHSHLEGEASLSEDEMAARPHTHLTHHELFGLKEIVMYLYDLPPQKKNVPSLVLDPVALIKDVRSLVERHCKDQQDLAITGVSVLKSPPGSQPPFLLYDRTRVKQEIKQEIARKNAEVIREQQQLEAGRAREAESDTSQSTGVGSVIGMGAGVEYSNGVMKKEQLENGSGVTVGGHGSQPEATFALPTDTLKYRPPKKMHLATALVAAAASSSSGGGGPVAGVGGSAVVGSSHSPTGGGVGPVTGAGGAISVIATSSSYIEGGQVGGILNMDNCHSPEGGGAKLSPNLTGTGQPRRRRTRCKNCAACQRSDCGTCPFCMDMVKFGGPGRAKQTCMMRQCLSPMLPVTAQCVYCHLDGWRQTPVSPQTKQLASADGPSALMECSVCYEIAHPDCALSQLDGTEDAADAKGIVNEDLPNSWECPSCCRSGKNYDYKPRHFR------------------------------------ARQKSSEVRRVSVSHGQGGAEGHADGNTLLPPPVGQYNDFVFTSESEMESGTVSGHMTHWKHGMKRHHQLEVKTERNNSCDTPSPGISPNAIGGDSKVGKRRKSDDGTSVSSSMHESNDAPCGSS-------------------AEGAGGAGNANVSTNQWSGSGGGGGSR------------------------------------------------------------------------------KKNSIRSQLAQQMLNSSTRVLKKPQYVVRP-----------------------------------ASGTGSSSSSGNGGSASATNGISNGSNQSGANSCGAGNGERGTNNGGLSGSNGLGN--QHYSSSQNLALDPTVLKIIFRYLPQDTLVTCCSVCKVWSNAAVDPDLWKKMNCSEHK-MSASLLTAIVRRQPEHLILDWTQIAKRQLAWLVARLPALKNLSLQNCPIQAVLALHTCLCPPLQTLDLSFVRGLNDAAIRDILSPPKDSRPGLSDSKTRLRDLKVMKLAGTDISDVAVRYITQSLPYLRHLDLSSCQRITDAGVAQIGTS-TTATARLTELNLSACRLVSENALEHLAKCEGLIWLDLRHVPQVSTQSVIRFASNS--KHDLCVRDIKLVERRRRNSTTANRSWHHD", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P40034-1", "uniprot_id": "JHD1_YEAST", "id": "P40034-1", "name": "JmjC domain-containing histone demethylation protein 1", "aln": "MQDPNICQHCQLKDNPGALIWVKCDSCPQWVHVKCVPLKRIHYSNLTSSEVLSYPNSAKQIKSYRCPNHKEGEYLTAYALITQKGKRQR-------NKENPEDSHINKRYNFRKKKLLDYIALNEGESKRDKMNHPHKESFMKSFEKWKNGSNIINAADFAEKFDNIDVPYKIIDPLNSGVYVPNVGTDNGCLTVNYITEMIGEDYHVDVMDVQSQMNENWNLGSWNEYFTNTEPDRRDRIRNVISLEVSNIEGLELER-PTAVRQNDLVDKIWSFNGHLEKVNGEKAEENDPKPKVTKYILMSVKDAYTDFHLDFAGTSVYYNVISGQKKFLLFPPTQSNIDKYIEWSLKEDQNSVFLGDILEDGIAMELDAGDLFMIPAGYIHAVYTPVDSLVFGGNFLTIRDLETHLKIVEIEKLTKVPRRFTFPKFDQVMG---KLCEYLALDKNKITSDVSDGDLLS----------------------------------------------------------------------------------------------------------------RTTNCAIQSLHAYVIKPEVKYKPLNFTSKKHLAKALADLIS-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . : *.* :. . *.. : * : *. . . ::: .: * : . . *: :*: ::*. : :*. :****. :* . : .: .* .*: :: .:::: ******.*: . : : * * * ** :*. : : : :. : *** ** *:**...:****:**.****:*:: * * * *:*** *:: * :* *. .* .:*:** : * * *.**:*:******* ::******** .: :*. :*. *:** :* :* : :: : . .:: : . . : . : : . : . : : . . ", "identical_positions": 92, "similar_positions": 116, "identity": "5.79%" }, { "cls_id": "homologset.agr.MGI:1354737", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q6P1G2-1", "uniprot_id": "KDM2B_MOUSE", "id": "Q6P1G2-1", "name": "Lysine-specific demethylase 2B", "aln": "--------------------MEAEKD-------------SGRRLRAIDRQRYDENEDLSDVEEIVSVRGFSLEEKLRS-QLYQGDFVHAMEGKDFNYEYVQREALRVPLVFRDKDGLGIKMPDP-DFTVRDVKLLVGSRRLVDVMDVNTQKGTEMSMSQFVRYYETPEAQRDKLYNVISLEFSHTKLEHLVKRPTVVDLVDWVDNMWPQHLKEKQTEATNALAEMKYPKVKKYCLMSVKGCFTDFHIDFGGTSVWYHVFRGGKIFWLIPPTLHNLALYEEWVLSGKQSDIFLGDRVERCQRIELKQGYTFFIPSGWIHAVYTPVDSLVFGGNILHSFNVPMQLRIYEIEDRTRVQPKFRYPFYYEMCWYVLERYVYCVTQRSYLTQEYQRELMLIDAPRKTSVDGFSSDSWLDMEEESCEQQPQEEEE--------------EEEDKEEEGDGADKTPKPPTDDPTSPTSTP-----------------------------------PEDQDSTGKKPKAPAIRFLKRTLSNESEESVKSTSMPTDDPKTPTGSPATEVSTKWTHLTEFELKGLKALVEKLESLPENKKCVPEGIEDPQALLEGVKNVLKEHVDDDPTLAITGVPVVSWPKKTAKNRVVGRPKGKLG---------PASAVKLAANRTTAG-ARRRRTRCRKCEACLRTECGECHFCKDMKKFGGPGRMKQSCIMRQCIAPVLPHTAVCLVCGEAGKEDTVEE------EEGKFNLMLMECSICNEIIHPGCLK--------IKESEGVVNDELPNCWECPKCNHAGKTG---KQKRGPGFKYASNLPGSLLKEQK-MNRDNKE-------GQEPAKRRSECEEAPRRRSDEHPKKVP----ADGILRRKSDD-VHLRRKRKYEKPQELSGRKRASSLQTSPG-SSSHLSPRPPLGSSLSPWWRSSLTYFQQQLKPG------KEDKLFRKKRRSWKNAEDRLSLANKPLRRFK---------QEPEDDLPEAPPKTR------------------ESDQSRSSSPTAGPSTEGAEGPEEKKKVKMRRKRRLV-NKELSKELSKELNHEIQKTESTLAHESQQPIKSEPE-SENDEPKRPL----------------------SHCERPHRFSKGLNGTPRELRHSLGPGLR----SPPRVMSRPPPSASPPKCIQMERHVIRPPPISPPPDSLPLDDGAAHVMHREVWMAVFSYLSHRDLCVCMRVCRTWNRWCCDKRLWTRIDLNRCKSITPLMLSGIIRRQPVSLDLSWTNISKKQLSWLINRLPGLRDLVLSGCSWIAVSALCSSSCPLLRTLDVQWVEGLKDAQMRDLLSPPTDNRPGQMDNRSKLRNIVELRLAG--LDITDVSLRLIIRHMPLLSKLQLSYCNHINDQSINLLTAVGTTTRDSLTEVNLSDCNKVTDLCLSFFKRCGNICHIDLRYCKQVTKEGCEQFIAEMSVSVQFGQVEEKLLQKLS-----------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0ABK0LIT9-1", "uniprot_id": "A0ABK0LIT9_RAT", "id": "A0ABK0LIT9-1", "name": "Lysine-specific demethylase 2B", "aln": "--------------------MEAEKD-------------SGRRLRAIDRQRYDENEDLSDVEEIVSVRGFSLEEKLRS-QLYQGDFVHAMEGKDFNYEYVQREALRVPLVFRDKDGLGIKMPDP-DFTVRDVKLLVGSRRLVDVMDVNTQKGTEMSMSQFVRYYETPEAQRDKLYNVISLEFSHTKLEHLVKRPTVVDLVDWVDNMWPQHLKEKQTEATNALAEMKYPKVKKYCLMSVKGCFTDFHIDFGGTSVWYHVFRGGKIFWLIPPTLHNLALYEEWVLSGKQSDIFLGDRVERCQRIELKQGYTFFIPSGWIHAVYTPVDSLVFGGNILHSFNVPMQLRIYEIEDRTRVQPKFRYPFYYEMCWYVLERYVYCVTQRSYLTQEYQRELMLIDAPRKNSVDGFSSDSWLEMEEESREQQLQEEE------------------DKEEEGDGADKTPKPPTEGPTSPTSTQ-----------------------------------SEDQDSTGKKPKAPAMRFLKRTLSNESEESVKSTAMPVDYPKTPTGSPATEVSTKWTHLTEFELKGLKALVEKLESLPENKKCVPEGIEDPQALLEGVKNVLKEHVDDDPNLAITGVPVVSWPKKTPKNRVVGRPKGKLG---------PASAVKLAANRTTAG-ARRRRTRCRKCEACLRTECGECHFCKDMKKFGGPGRMKQSCIMRQCIAPVLPHTAVCLVCGEAGKEDTVEE------EEGKFNLMLMECSICNEIIHPGCLK--------IKESEGVVNDELPNCWECPKCNHAGKTGKAYKQKRGPGFKYASNLPGSLLKEQK-MNRDNKE-------GQEPAKRRSECEEAPRRRSDEHPKKVP----TDGILRRKSDD-VHLRRKRKYEKPQELSARKRASTLQTSPG-SSSHLSPRPPLGSSLSPWWRSSLTYFQQQLKPG------KEDKLLRKKRRSWKNAEDRLSLANKPLRRFK---------QEPEDDLPEAPPKTR------------------ESDQSRSSSPTAGPSTEGAEGPEEKRKVKMRRKRRLP-NKELSKELSKELNHEIQKTESTLAHENHQPIKSEPE-SENEEPKRPL----------------------SHCERPHRFSKGLNGTPRELRHSLGPGLR----SPPRVISRPPPSTSPPKCIQMERHVIRPPPISPPPDSLPLDDGAAHVMHREVWMAVFSYLSHQDLCVCMRVCRTWNRWCCDKRLWTRIDLNHCKSITPLMLSGIIRRQPVSLDLSWTNISKKQLSWLINRLPGLRDLVLSGCSWIAVSALCSSSCPLLRTLDVQWVEGLKDAQMRDLLSPPTDNRPGQMDNRSKLRNIVELRLAG--LDITDVSLRLIIRHMPLLSKLHLSYCNHVTDQSINLLTAVGTTTRDSLTEINLSDCNKVTDQCLSFFKRCGNICHIDLRYCKQVTKEGCEQFIAEMSVSVQFGQVEEKLLQKLS-----------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8NHM5-1", "uniprot_id": "KDM2B_HUMAN", "id": "Q8NHM5-1", "name": "Lysine-specific demethylase 2B", "aln": "--MAGPQMGGSAEDHPPRKRHAAEKQKKKTVIYTKCFEFESATQRPIDRQRYDENEDLSDVEEIVSVRGFSLEEKLRS-QLYQGDFVHAMEGKDFNYEYVQREALRVPLIFREKDGLGIKMPDP-DFTVRDVKLLVGSRRLVDVMDVNTQKGTEMSMSQFVRYYETPEAQRDKLYNVISLEFSHTKLEHLVKRPTVVDLVDWVDNMWPQHLKEKQTEATNAIAEMKYPKVKKYCLMSVKGCFTDFHIDFGGTSVWYHVFRGGKIFWLIPPTLHNLALYEEWVLSGKQSDIFLGDRVERCQRIELKQGYTFFIPSGWIHAVYTPVDSLVFGGNILHSFNVPMQLRIYEIEDRTRVQPKFRYPFYYEMCWYVLERYVYCVTQRSHLTQEYQRESMLIDAPRKPSIDGFSSDSWLEMEEEACDQQPQEEE------------------EKDEEGEGRDRAPKPPTDGSTSPTSTP-----------------------------------SEDQEALGKKPKAPALRFLKRTLSNESEESVKSTTLAVDYPKTPTGSPATEVSAKWTHLTEFELKGLKALVEKLESLPENKKCVPEGIEDPQALLEGVKNVLKEHADDDPSLAITGVPVVTWPKKTPKNRAVGRPKGKLG---------PASAVKLAANRTTAG-ARRRRTRCRKCEACLRTECGECHFCKDMKKFGGPGRMKQSCIMRQCIAPVLPHTAVCLVCGEAGKEDTVEE------EEGKFNLMLMECSICNEIIHPGCLK--------IKESEGVVNDELPNCWECPKCNHAGKTG---KQKRGPGFKYASNLPGSLLKEQK-MNRDNKE-------GQEPAKRRSECEEAPRRRSDEHSKKVP----PDGLLRRKSDD-VHLRKKRKYEKPQELSGRKRASSLQTSPG-SSSHLSPRPPLGSSLSPWWRSSLTYFQQQLKPG------KEDKLFRKKRRSWKNAEDRMALANKPLRRFK---------QEPEDELPEAPPKTR------------------ESDHSRSSSPTAGPSTEGAEGPEEKKKVKMRRKRRLP-NKELSRELSKELNHEIQRTENSLANENQQPIKSEPE-SEGEEPKRPP----------------------GICERPHRFSKGLNGTPRELRHQLGPSLR----SPPRVISRPPPSVSPPKCIQMERHVIRPPPISPPPDSLPLDDGAAHVMHREVWMAVFSYLSHQDLCVCMRVCRTWNRWCCDKRLWTRIDLNHCKSITPLMLSGIIRRQPVSLDLSWTNISKKQLSWLINRLPGLRDLVLSGCSWIAVSALCSSSCPLLRTLDVQWVEGLKDAQMRDLLSPPTDNRPGQMDNRSKLRNIVELRLAG--LDITDASLRLIIRHMPLLSKLHLSYCNHVTDQSINLLTAVGTTTRDSLTEINLSDCNKVTDQCLSFFKRCGNICHIDLRYCKQVTKEGCEQFIAEMSVSVQFGQVEEKLLQKLS-----------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AB32U022-1", "uniprot_id": "A0AB32U022_DANRE", "id": "A0AB32U022-1", "name": "", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MAMAMSLSADDEDYDSDTAEQQ---------------------------QLPNKPKPKMATSTATTP-----------------------------------SATTSSS----------------------------------------------------------------------------------------------------------------------------------------------TATAVKLPSNRTSSG-ARRRRTRCRKCEACVRTECGECHFCKDMKKFGGPGRMKQSCIMRQCIAPVLPHTAVCVVCGEAGKEDTLDD------EDEKFNAMLMECSICNEIVHPNCLK--------VKDAAGVVNDELPNCWECPKCNYAGKTGKACKQKRGPGFKYASNLPGSLLREQK-AGRDGREEGDQTSTGPASIKRKTEREETPRLKTEDLPSRLPPLLSPSGLPRPRSEVPNFLRKKRKLFDDDEEEEEASAKKKQKKPWRPEEPLIPKLSHMKAEEEEDNSDEEEERQEKREQPRRSIKKDYSIVRKEEEREEDRREDRDPPFRSLKEFHNMSKEEDHDEEKEDDDEEEEEESNGKRGRDSSPALKNLSLSLESDASRCSSPRAGPSSEGSETQEKAPRARARRHRRKPPNRQLSAELSKQLNMEIRRTEHSLANENQQPLMSEPEDSENEEPKRGLRNGTAGNAGGGGGGVERGAGGEAGGERPHLRAREMNGTSWELRHFYPPQITPLGLNRSSPTVRPLPARSPPKCVQMERHVIRPPPICPPPDRLPLADGRNHIAPREAWLAIFSHLSHRELCVCMRVCRTWNRWCCDKRLWTRIDLKRCKSITPLMLSGIIRRQPITLDLSWTNISKKQLSWLINRLPGLRVLLLSGCSWVAVSALCTSSCPLLRTLDLQWVEGLKDPQMRDLLSPPTDNRPGQMDTRSKLRNVTDLRLAG--LDITDSSLRLIIKNMPLLSRLDLSYCNHINDQSVNLLTAAGTTTRDSLTDVNLSVCNRVTDQSLSYFKRCGSICRIDMRFSKQVSRQACERFIAEMSVIVPFQLQEDKLLQKLHSTP--------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0AB32TVL5-1", "uniprot_id": "A0AB32TVL5_DANRE", "id": "A0AB32TVL5-1", "name": "Lysine-specific demethylase 2B", "aln": "--------------------MEACAE-------------SGRKLRSICRRMYDENEDLSDVEEITNVRGFSLEDKLDS-ASYNSQLVQFMEGKDFTYEYVQREALRTPLVFKAKDGLGIRMPDP-EFTVSEIKGLVGSRRPVDVMDVSTQKGSEMSMAQFVRYYETPEDERDKLFNVISLEFSHTKLENLIKRPTVVDLVDWVDNMWPRHLKQKQTEATNVMSEMKYPKVQRYCLMSVKGCFTDFHIDFGGTSVWYHVFKGQKVFWLIPPNAHNLSLYEDWVLSGKQSDIFLGDRADGCQRVELKQGYTFFIPSGWIHAVYTPEDTLVFGGNILHSFNIPMQLTVYEIENRTKVHSKFRYPFFYEMCWYVLERYVSCLTKRSHLSLEFRN----HTAEPKPVTESLMSATRLDMEEDSCGTEGTILS-----------------------------SFSIPPCQTFKPSAND-----------------------------------SEDSSKS----------------------------LPSECPKTPSGSPGMDHSGKWSHLTEFELNGLKALVEKLESLPENKKCVPEGIEDPQALLDDVKVVLKEHADDNPKLAISGSPIVCWPKKTFKPRPLNRPKPKMGSSPCAAPGSTAGGMKLSSGRGSSS-ARRRRTRCRKCEACTRKECGECHFCKDMKKFGGPGRMKQSCIMRQCIAPVLPHTAVCVVCGEAGKEDTVEG------EDDKFSMMLMECSICSEIIHPACLK--------DKDAGGVVNDELPNCWECPKCNHAGKTGKATKQKRGPGFKYASNLPGSLLKEQRTIIKEEPDMSTETAAVSPITKRKTEDDDNPTCKSEDAIKKRS----------PKLED-NPLRKKRKLFEKDSDSNSIIRKKKKRTNP---DDLSTSLILGHIKKE--REDDEEYEEQNQPE--------RSFVPSEEEDGDDERDEEE-EEKALSSRK--------------ENGKVSHKTL------------------ESDQSQGGLTQAGPSSTDAQSKSQR---KAKRKPRLP-NKELSKELSKQLNQEIQKTEDRLAHQNGRTVKTEPS-SDGEDRKPLN----------------------NGSSHLRDWLGPKWELNGSLREQTPVSLIR--TTTPAPVFRPTPCRSPPKCVQMERHVIRPPPISPPPDRLPLDDGKNHVLRREVWMGVFSHLIHKDLCVCMSVCKTWNRWCCDKRLWTKIDLNRCKSITPLMLSGIIRRQPVSLDLSWTNISKKQLSWLINRLPGLRVLLLAGCSWAAVSALCTSSCPLLRNLDVQWVEGLKDNQIRDLLSPPTDNRPGQLDCRSKLRNVEDLCLAG--LDITDTSLKLIIKHMPLLSQLDLSYCNHITDHSVNILTAAGTTTRDSLTHINLSVCNRVTDLSLTYFKRCGNICQIDLRYCKQVTKEGCEQFIAEMSVSVQFRLMEEKLLSKLS-----------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VHH9-1", "uniprot_id": "JHD1_DROME", "id": "Q9VHH9-1", "name": "JmjC domain-containing histone demethylation protein 1", "aln": "MSTAVETGSSPAKSNSNNSSSGGNNNNGNGNLSPNAKGVQRRQLRERKQRKLYLEEWSLGDEDGEGTRGFSVAEKLESSKFAQAGMVREMRGCDLTVAFLQQHGFNIPLLFRDKAGLGLRMPDPQEFTVNDVRLCVGSRRLLDVMDVNTQKNLQMTMKEWQQYYDSP--QKDRLLNVISLEFSHTRLDRFVQSPEIVRQIDWVDVVWPKQLKDAQREGTNLLGGMMYPKVQKYCLMSVKNCYTDFHIDFGGTSVWYHILRGSKVFWLIPPTDRNLQLYEKWVLSGKQADIFFGDTVEKCARVYLTAGNTFFIPTGWIHAVYTPTQSLVFGGNFLHSFGIVKQLKTASVEDSTKVPQKFRYPFFTEMLWYVLARYVHTLLGHSHLEGEASLSEDEMAARPHTHLTHHELFGLKEIVMYLYDLPPQKKNVPSLVLDPVALIKDVRSLVERHCKDQQDLAITGVSVLKSPPGSQPPFLLYDRTRVKQEIKQEIARKNAEVIREQQQLEAGRAREAESDTSQSTGVGSVIGMGAGVEYSNGVMKKEQLENGSGVTVGGHGSQPEATFALPTDTLKYRPPKKMHLATALVAAAASSSSGGGGPVAGVGGSAVVGSSHSPTGGGVGPVTGAGGAISVIATSSSYIEGGQVGGILNMDNCHSPEGGGAKLSPNLTGTGQPRRRRTRCKNCAACQRSDCGTCPFCMDMVKFGGPGRAKQTCMMRQCLSPMLPVTAQCVYCHLDGWRQTPVSPQTKQLASADGPSALMECSVCYEIAHPDCALSQLDGTEDAADAKGIVNEDLPNSWECPSCCRSGKNYDYKPRHFRARQKSSEVRRVSVSHGQG---------------GAEGHADGNTLLPPPVGQYNDFVFTSE----SEMESGTVSGHMTHWKHGMKRHHQLEVKTERNNSCDTPSPG-----ISPNAIGGDSKVGKRRKSDDGTSVSSSMH-------------------------------------------------------------------------------ESNDAPCGSSAEGAGGAGNANVSTNQWSGSGGGGGSRKKNSIRSQLAQQMLNSSTRVLKKPQYVVRPASGTGSSSSSGNGGSASATN--------------------GISNGSNQSGANSCGAGNGERGTNNGGLSG----------------------------------SNGLGNQHYSSSQNLALDPTVLKIIFRYLPQDTLVTCCSVCKVWSNAAVDPDLWKKMNCSEHK-MSASLLTAIVRRQPEHLILDWTQIAKRQLAWLVARLPALKNLSLQNCPIQAVLALHTCLCPPLQTLDLSFVRGLNDAAIRDILSPPKDSRPGLSDSKTRLRDLKVMKLAG--TDISDVAVRYITQSLPYLRHLDLSSCQRITDAGVAQIGTS-TTATARLTELNLSACRLVSENALEHLAKCEGLIWLDLRHVPQVSTQSVIRFASNSKHDLCVRDIKLVERRRRNSTTANRSWHHD", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P40034-1", "uniprot_id": "JHD1_YEAST", "id": "P40034-1", "name": "JmjC domain-containing histone demethylation protein 1", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MQDPNICQHCQLK---------------DNPGALIWVKCDSCPQWVHVKCVP---------------LKRIHYSNLTSSEVLSYPNSAKQIKSYRCPNHKEGEYLTAYALITQK---------------GKRQRNKENPEDSHINKRYN--------------------------FRKKKLLDYIALNEGESKRDKMNHPH---------------KESFMKSFEKWKNGSNIIN-------------------------------------------------------------------------------AADFAEKFDNIDVPYKIIDPLNSGVYVPNVGTDNGCLTVNYITEMIGEDYHVDVMDVQSQMNENWN------------------------------------------LGSWNEYFTNTEPDRRDRIRNVISLEVSN-------------------------------------IEGLELER-PTAVRQNDLVDKIWSFNGHLEKVNGE-----------------KAEENDPKPKVTKYILMSVKDAYTDFHLDFAGTS-----VYYNVISGQKKFLLFPPTQSNIDKYIEWS--LKEDQNSVFLGDILEDGIAMELDAGDLFMIPAGYIHAVYTPVDSLVFGGNFLTIRDLETHLKIVEIEKLTKVPRRFTFPKFDQVMGKLCEYLALDKNKITSD-------VSDGDLLSRTTNCAIQSLHAYVIKPEVKYKPLNFTSKKHLAKALADLIS------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . * * . ::*. * : * * :: . ... :. . * .. * . : : : * . . .. . :: : . . . : :.:: . . . . * : :: . : : : . * . : :: : *.:: : :.. : : * . : . : :: .: : : *.. :: : : :.* * * : : * :: * : : : :* *:: * : :. .* :: . ", "identical_positions": 23, "similar_positions": 99, "identity": "1.53%" }, { "cls_id": "homologset.agr.MGI:1354738", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "F7FJ48-1", "uniprot_id": "F7FJ48_RAT", "id": "F7FJ48-1", "name": "F-box/LRR-repeat protein 12", "aln": "-----------------------------------------------------------------MATLFDLPDLVLLEIFSYLPVRDRIRISRVCHRWKRLVDDRWLWRHVDLTLYTMRPKVMWHLLRRYMASRLHSLRMGGYLFSGSQAPQLS--PALMRALGQKCPNLKRLCLH--VADLSMVPITSLPSTLRTLELHSCEISMIWLQK---EQDPTVLPLLECIVLDRVPAFRDEHLQGLTRFRALRSLVLGGTYRVTETGLDSSLQELSYLQRLEVLGCTLS------------------------------------------------------------ADSTLLAISRHLRDVRKIR-------------------------LTVGGLSAQG-------------------LVFLEGMPVLESLCFQGPLITPEMPTPAQIVSSCLTMPKLRVLEVQGLG------------------------WEGQEAEKVLCKGLPHCLVIVRACPKESMDWWM--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9EPX5-1", "uniprot_id": "FXL12_MOUSE", "id": "Q9EPX5-1", "name": "F-box/LRR-repeat protein 12", "aln": "-----------------------------------------------------------------MATLFDLPDLVLLEIFSYLPVRDRIRISRVCHRWKRLVDDRWLWRHVDLTLYTMRPKVMWHLLRRYMASRLYSLRMGGYLFSGSQAPQLS--PALMRALGQKCPNLKRLCLH--VADLSMVPITSLPSTLRTLELHSCEISMIWLQK---EQDPTVLPLLECIVLDRVPAFRDEHLQGLTRFRALRSLVLGGTYRVTETGLDASLQELSYLQRLEVLGCTLS------------------------------------------------------------ADSTLLAISRHLRDVRKIR-------------------------LTVGGLSAQG-------------------LVFLEGMPVLESLCFQGPLITPDMPTPTQIVSSCLTMPKLRVLEVQGLG------------------------WEGQEAEKILCKGLPHCIVIVRACPKESMDWWM--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9NXK8-1", "uniprot_id": "FXL12_HUMAN", "id": "Q9NXK8-1", "name": "F-box/LRR-repeat protein 12", "aln": "-----------------------------------------------------------------MATLVELPDSVLLEIFSYLPVRDRIRISRVCHRWKRLVDDRWLWRHVDLTLYTMRPKVMWHLLRRYMASRLHSLRMGGYLFSGSQAPQLS--PALLRALGQKCPNLKRLCLH--VADLSMVPITSLPSTLRTLELHSCEISMAWLHK---QQDPTVLPLLECIVLDRVPAFRDEHLQGLTRFRALRSLVLGGTYRVTETGLDAGLQELSYLQRLEVLGCTLS------------------------------------------------------------ADSTLLAISRHLRDVRKIR-------------------------LTVRGLSAPG-------------------LAVLEGMPALESLCLQGPLVTPEMPSPTEILSSCLTMPKLRVLELQGLG------------------------WEGQEAEKILCKGLPHCMVIVRACPKESMDWWM--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VAZ0-1", "uniprot_id": "Q9VAZ0_DROME", "id": "Q9VAZ0-1", "name": "F-box domain-containing protein", "aln": "MEQAELGSTCLAAPKRRFPDNERCGRELAAVPVQPVLPQIPTEEEPEIKQRKREKEHKESLDRETECNLMDFCDELLFEIFQYLDTSSILAVMHCSPRFENLLLDHRFYHHIDLSNGPLPMGILEEILGR-ATEKTHTIKICGPPSSQHVAGEFRQFTQTLSSVFPRVVQLKVLELEGVSLDFEYIHITEFPATLRRLKLKDCSVRVGDTPKSIFYSIELHLLDLEDLSIEDNSWFEPYYIMGLSKLPSLRRLSLKGCQALCKFVPYGSMAARFGFQKLESLDLRQTPINNSDLQCFSAIENLKELLLESPQILHSKQAVAKKNTNGNATDEAASPQPDSLKVLSDDEPSTSRAAMEHLRACKVAFNLDNCSDRKEEKSPVPTEPPSEGQDLQAKRIRAPSESDDEDTSSTSGSSSDKLEVLSLPRNGHSNAAPLSGGVDLPPLPHAADAANAADAPIAVDAANIEAPGQSPGLDPRPPRAYIYVPDAENANPRQQRSVVAVFAQGTEQRYIYVNQQFSLPMNVLMPTRRHRTHPRPNYDQVVQHPMFWNMLEPLDRDYARRVRPRPPSCQTTPQYYVTDRAMYSFGRADRPVQPDVVWIRNINRSPDNKLERLSLRNYHLITNHTLEHLVQCSPNLVYIDVSGTSITLPAIRRFKISKPKCEVVANHLEEFERLPELETQEEDDTVVVMLQPPPRADDEQPPKSPPPQEVVAP", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ..*.:: * :*:***.** . . : : : . *::.*: *: :::*:**: .: :: .:* * :.: ::::: * * * :: . : :: : :** * *. *:. : **.:*:*** *:*:.*.: : * . * ** : :: . *. :: **::: :** * * * : : ..: :*:** *. : ** * .*** : * . : * . : * :: :.* : * :* .:: .:. : : . :::. * : :.. ::.:* : : *. . .*: * ", "identical_positions": 66, "similar_positions": 119, "identity": "9.24%" }, { "cls_id": "homologset.agr.MGI:1354739", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P49807-1", "uniprot_id": "RGS11_RAT", "id": "P49807-1", "name": "Regulator of G protein signaling 11", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------EACEELRFGGQAQVPTLVDSVYQQFLAPGAARWINIDSRTMEWTLEGLRQPHRYVLDAAQLHIYML-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9Z2H1-1", "uniprot_id": "RGS11_MOUSE", "id": "Q9Z2H1-1", "name": "Regulator of G protein signaling 11", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MERVVVSMQDPDQGVKMRSQRLLITVIPHAVAGRDLVEWLVQKFCILEDEALHLGTLLAQHGYIYPLRESRDLTLRPDETPYRFQTPYFWTSTMWPAAELDYAIYLAKKNIQ--KQGALVDYEKEHYALLHKKINHAWDLVLMQAREQLRAAKQRRKGDRMVISCQEQTYWLVNKPPPGAPNILEQGPE-RGSYNPS--HMQMSSDFYKCEIECFRKALGRNRVKSSACLEAYLKFSSQHGPHDPIMSGCLPSNPWITDDVTYWAMNAPNVAAPTKLRVERWSFSFRELLDDPVGRAHFMDFLQKEFSAENLSFWEACEELRFGGQAQVPTLVDSVYQQFLAPGAARWINIDSRTMERTLEGLRQPHRYVLDAAQLHIYMLM-KKDSYPRFLKSDIYKGLLEEAVIP--------------------------------------------------------------------------------------------------------------------------------------LETKRWPFPFLRKPLHSSPSPALQS-----------------------------------TPRE----PAATSSPEGADGE----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O94810-1", "uniprot_id": "RGS11_HUMAN", "id": "O94810-1", "name": "Regulator of G protein signaling 11", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MAAGPAPPPGRPRAQMPHLR------KMERVVVSMQDPDQGVKMRSQRLLVTVIPHAVTGSDVVQWLAQKFCVSEEEALHLGAVLVQHGYIYPLRDPRSLMLRPDETPYRFQTPYFWTSTLRPAAELDYAIYLAKKNIR--KRGTLVDYEKDCYDRLHKKINHAWDLVLMQAREQLRAAKQRSKGDRLVIACQEQTYWLVNRPPPGAPDVLEQGPG-RGSCAASRVLMTKSADFHKREIEYFRKALGRTRVKSSVCLEAYLSFCGQRGPHDPLVSGCLPSNPWISDNDAYWVMNAPTVAAPTKLRVERWGFSFRELLEDPVGRAHFMDFLGKEFSGENLSFWEACEELRYGAQAQVPTLVDAVYEQFLAPGAAHWVNIDSRTMEQTLEGLRQPHRYVLDDAQLHIYMLM-KKDSYPRFLKSDMYKALLAEAGIP--------------------------------------------------------------------------------------------------------------------------------------LEMKRRVFPFTWRPRHSSPSPALLP-----------------------------------TPVE----PTAACGPGGGDGVA---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M3B6U8-1", "uniprot_id": "A0A8M3B6U8_DANRE", "id": "A0A8M3B6U8-1", "name": "", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MTINTLSQDGVQRQQMPCLT------KMERMIISMQDPDMGIKLRNQRLLITVIPHAMTGADIVEWLIKKLTIS-DEAAHIGQFLVKYGYIYPLKEPRNLILKADESAYRFQTPYYWMSTRWPASELDYAIYLAKKNIR--KQGELIEYEKECYNALHKRINHTWDFVVMQAREQLRASKQRRKADRIVLECQEQAFWLVNRPPPGTLDIMNYGPE-RRTMNTR---VQLNAEFYKKEIEHNRMSLARNRVKSSICLESYVKYCEQYQPHDPIMQGCLPSNPWITDDVLFWNMNSEAVTVPTKLRVERWSFSFTELLDDPMGRKEFLIYLEKEFSAENLCFWQACEDVRHGESSKIPEKVDEVYKQFLAPGASRWVNIDSKTMEKTLEGLKRPHRFVLDDAQMHIYFLM-KKDSFPRYLKSDLYKSLLARAIVP--------------------------------------------------------------------------------------------------------------------------------------QETKKSVFPFMRRQRHSSPSPALVT-----------------------------------HTTEDDGKAKNSNSVKSNSGTASRL------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "M9PHI8-1", "uniprot_id": "M9PHI8_DROME", "id": "M9PHI8-1", "name": "Regulator of G-protein signaling 7", "aln": "MEPPGGVPPDRDRQLVLRNQSAALVPVVVSAPATGPGATTPNPQSSAQAQLSLVPSKPTSLSLQPHAVLQAMQQLSPSAGGNNNASSTAATATSSSSGNANSGSSPALASTATAISATTQAATAFSGSSVGHHHLQHHHQHTHPHAPQQSQSQQPQPQHQLQQPHPAGAPSSATQSHHHGSISVSGSGGGLLGSSGGSGNQQQAIEKLSRPMAFDKMEMLVREMQDQEHGVPVRQQKMFLTSIPYAFMGYDLIEWLMDRLQIEESEALNIANQLCLHGYFFPVNDSKTLTVKDDSSLYRFQTPYYWPWQHKAPDNVEYAIYLAKRSLRNKQRHALEDYEAEALASLHKNLKGKWDFISMQAEEQVRLAKERKKGDKIVGDSQERAYWRVHRPPPGQFTPLEPCPVPSRDRQGLKPNKKKTVDDMQRDVDYLGKSLNRTRMKMSQACESLVCYSETFSEYDFFLQPALPSNPWVTEDIAFWQLNNTFVDIPTEKRVKRWAISIEELVSDPTGLQEFTGFLEKEYSHENIRFWIAVNRLRRSAHSQVARKVNEIYEEFLKPGAPCEINIDGKTMESVLKGLKNPSRFTFDSASEHIYMLLLKKDCYPRFIRSEHYKRLLDTGIQPSYKKRFFNFGGVSGAKKKMTAALSSQPNLGDAAKGPSGTSAGSSMMQAPPPGNLARRRGSDRSLTGSAHELAVIGVNKDAGSKVPHSHSQSNLSEIPFSSDSIYRGDMPQRHMAIMDIGIYAAYGNRESSLQALPETPKTKTTVLDATESTSSSTALAAAASSAVCPWDDPAESVPPPPPPAQVKLSVCPWELDSATETPTAAPAVGSGGGGAGASKILSSTGQPMRLNSTSSDNSDVNDRMQRNLGIRHQNTVDSGEAGIKRLIPNIPEQRRASVSFTPSPTPDFQLGRTPTTTSSPTVAPSSSTPLQARSAVYGSGQGIAKDPPSGSDVDAELEEELNKISLGESSISEPPLLVVPTPEQTPPPITKITPPPGESENQADQVIDSTEIPGSSCSTQANQFGEATATVTTVKEVQIELIEQVSGVQTEPDSPPTIKVLVLEATTPVSAETATADPGENLAKMATASNTTTITTDDQAMRADDDAERAAEIEQTVLDELSPTTDEYQEFGDAKDAVDDFDSIDIGYIPPAPTPAPSMAPLAELDVDTVDDEPCEPAAPPPSHSAPASSSSRELVMASGSVTATPTSSNEEARKRRKKRNSEGKKLSSQDDKDKDAHERAGGSSMDAADHNAVCPWEDENVSTNDGTFVKTYATLGYL", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * : :* . :::. *: :*::** ***. :***.:*** .*:**:.* *:.:* *. ***:* ", "identical_positions": 26, "similar_positions": 24, "identity": "2.03%" }, { "cls_id": "homologset.agr.MGI:1354740", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P55822-1", "uniprot_id": "SH3BG_HUMAN", "id": "P55822-1", "name": "SH3 domain-binding glutamic acid-rich protein", "aln": "MPLLLLGETEPLKLERDCRSPVDPWAAASPDLALACLCHCQDLSSGAFPDRGVLGGVLFPTVEMVIKVFVATSSGSIAIRKKQQEVVGFLEANKIDFKELDIAG--DEDNRRWMRENVPGE----KKPQNGIPLPPQIFNEEQYCGDFDSFFSAKEENIIYSFLGLAPPPDS--------------------------------------------------------KGSEKAEEGGETEAQK------EGSEDVGNLPEAQEKNEEEGE-----------------TATEETEEIAMEGAEGEAEEEEETAEGEEPGEDEDS------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9WUZ7-1", "uniprot_id": "SH3BG_MOUSE", "id": "Q9WUZ7-1", "name": "SH3 domain-binding glutamic acid-rich protein", "aln": "---------------------------------------------------------------MVIKVFVATSSGSIAIRKKQQEVVGFLEANKIDFKELDIAG--DEDNRKWMRENVPGE----KKPQNGIPLPPQIFNEEQYCGDFDSFFSAKEENIIYSFLGLAPPPGSKVTKSEEASSLPNGDVAGEAE--------------------------------GAAEGTEKAEKSGENEAQK------EDSEDTGELSESQEKKEEEGEDGEEGEEGEEREEGGEGETTGETEEAPEEGAGGEAEEEE--PE-EEAGEGEDS------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D4AAC3-1", "uniprot_id": "D4AAC3_RAT", "id": "D4AAC3-1", "name": "", "aln": "---------------------------------------------------------------MVIKVFVATSSGSIAIRKKQQEVVGFLEANKIDFKELDIAG--DEDNRKWMRENVPGE----KKPQNGIPLPPQIFNEEQYCGDFDSFFSAKEENIIYSFLGLAPPPGSKVTKSEEASSLPNGDVAGEAEGAAEVRRRLKKVEKLRHRKRTVKTLASFLNPKRRRKKREKREKREKRERQQKRRKRQQREEQREKLKKNPRKREEKRKILRLFRLVPQLSQDIQASRPHLNSLSSFNSMKYSAGSQP--PSPSTPGFTEDPCPPKQLGVCESLSHRVNMRLDVKTAHMLCLRFMLFA", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0A8M2BH31-1", "uniprot_id": "A0A8M2BH31_DANRE", "id": "A0A8M2BH31-1", "name": "", "aln": "---------------------------------------------------------------MVIKVFLASSSGSTAIKKKQQDVVGFLEALKIDYAQLDIAS--NEDNRAWMRENVPGE----KKPTNGIPLPPQIFNEEMYCGDYDTFFDAKEDNTVYEFLGLTPPPGSKEAQQAENSQKLQNGSVTEEH------------------------------------PDDDTTKIELKEAEQ------NGDAHTAELEEDEESKNAETDAQDENEEEEEPAEEEEESRKPAEEEEQEEAEGDKVEDNHLVSEAEDELVSEEEEELRELEEEEEHPSEED-------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9NFP5-1", "uniprot_id": "SH3BG_DROME", "id": "Q9NFP5-1", "name": "SH3 domain-binding glutamic acid-rich protein homolog", "aln": "---------------------------------------------------------------MVLKVYVSGMSGNKEVKKRQQRVLMILDSKNIKYDTVDITEPGKESEKELMQNKSTSNGGTVSDPEPRHPLPPQLFNDDEYCGDYDAFDMANEIDTLEVFLKLAPADTT--------------------------------------------------------------------------------AVSTAQIELKQENGDAKKE-----------------EAETEAEDKKTEAGDGDVDVKEEAAEKAEV------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " **:**::: **. ::*:** *: :*:: :*.: :**: .*.:: *::: ..: ..* *****:**:: ****:*:* *:* : : ** *:*. : :: .. : : . . :. .. : .. ", "identical_positions": 36, "similar_positions": 55, "identity": "10.0%" }, { "cls_id": "homologset.agr.MGI:1354742", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9UMZ2-1", "uniprot_id": "SYNRG_HUMAN", "id": "Q9UMZ2-1", "name": "Synergin gamma", "aln": "MALRPGAGSGGGGAAGAGAGSAGGGGFMFPVAGGIRPPQAGLMPMQQQ---GFPMVSVMQPNMQGIMGMNYSSQMSQGPIAMQAGIPMGPMPAAGMPYLGQAPFLGMRPPGPQYTPDMQKQFAEEQQKRFEQQQKLLEEERKRRQFEEQKQKLRLLSSVKPKTGEKSRDDALEAIKGNLDGFSRDAKMHPTPASHPKKP----------------------------------------------------------------------------------------------------GPSLEEKFLVSCDISTSGQEQIKLN----TSEVGHKALGPG---SSKKYPSLMASNGVAVDGCVSGTTTAEAENTSDQNLS-------IEESGVGVFPSQDPAQPRMPPWIYNESLVPDAYKKILETTMTPTGIDTAKLYPILMSSGLPRETLGQIWALANRTTPGKLTKEELYTVLAMIAVTQRGVPAMSPDALNQFPAAPIPTLSGFSMTLPTPVSQP-TVIPSGPAGSMPLSLGQP-VMGINLVGPVGGAAAQASSGFIPTYPANQVVKPEEDDFQDFQDASKSGSLDDSFSDFQ-ELPASSKTSNSQHGNSAPSLLMPLPGTKALPSMDKYAVFKGIAADKSSENTVPPGDPGDKYSAFRELEQTAENKPLGESFAEFRSAGTDDGFTDFKTADSVSPLEPPTKDK---TFPPSFPSG----TIQQKQQTQVKNPLNLADLDMFSSVNCSSEKPLSFSAVFSTSKSVST-PQSTGSAATMTALAATKTSSLADDFGEFSLFGEYSG------------LAPVGEQDDFADFMAFSNSSISSEQKPDDKYDALKEEASPVPLTSNVGSTVKGGQNSTAASTKYDVFRQLSLEGSGLGVEDLKDN----TPSGKSD-DDFADFHSSKFSSIN--SDKSLGEKAVAFRHTKEDSASVKSLDLPSIGGSSVGKEDSEDALSVQFDMKLADVGGDLKHVMSDSSLDLPTVSGQHPPAADIEDLKYAAFGSYSSNFAVSTLTSYDWSDRDDATQGRKLSPFVLSAGSGSPSATSILQKKETSFGSSENITMTSLSKVTTFVSED--ALPETTFPALASFKDTIPQTSEQKEYENRDYKDFTKQDLPTAERSQEATCPSPASSGASQETPNECSDDFGEFQSEKPKISKFDFLVATSQSKMKSSEEMIKSELATFDLSVQGSHKRSLSLGDKEISRSSPSPALEQPFRDRSNTLNEKPALPVIRDKYKDLTGEVEENERYAYEWQRCLGSALNVIKKANDTLNGISSSSVCTEVIQSAQGMEYLLGVVEVYRVTKRVELGIKATAVCSEKLQQLLKDIDKVWNNLIGFMSLATLTPDENSLDFSSCMLRPGIKNAQELACGVCLLNVDSRSRKEEK---------------------------PAEE-----HPKKAFNSETDSFKLAYGGHQYHASCANFWINCVEPKPPGLVLPDLL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q5SV85-1", "uniprot_id": "SYNRG_MOUSE", "id": "Q5SV85-1", "name": "Synergin gamma", "aln": "MALRPGAGASG--AAGAGAGPGGAGSFMFPVAGGMRPPQAGLIPMQQQ---GFPMVSVMQPNMQGMMGMNYSSQMSQGPIAMQAGIPMGPMPAAGVPFLGQPPFLSMRPAGPQYTPDMQKQFAEEQQKRFEQQQKLLEEERKRRQFEEQKQKLRLLSSVKPKTGEKNRDDALEAIKGNLDGFSRDAKMHPTPASHPKKQ----------------------------------------------------------------------------------------------------GPSLEEKLLVSCDVSASGQEHIKLN----TPDAGHKAIVPG---SSKNCPGLMAHNRGAVDGCVSGPASAEAEKTSDQTLS-------KEESGVGVFPSQDPAQSRMPPWIYNESLVPDAYKKILETTMTPTGIDTAKLYPILMSSGLPRETLGQIWALANRTTPGRLTKEELYTVLAMVAVTQRGVPAMSPDALSQFPAAPIPTLSGFPMTLPTPVSQP-TAMPSGPTGSMPLTLGQP-IMGINLVGPVGGAAAPTSSGFMPAYPSNQVGKTEEDDFQDFQDASKSGSIDDSFTDFQ-EMPASSKTSNSQHGNSAPSLLIPFPGTKAS--TDKYAVFKGISTDKPSENPASFGESGDKYSAFRELEQTTDSKPLGESFAEFRSTGTDDGFTDFKTADSVSPLEPPTKD----TFPSAFASG----AAQQT-QTQVKTPLNLEDLDMFSSVDCSGEKQVPFSATFSTAKSVSTRPQPAGSAAASAALASTKTSSLADDFGEFNLFGEYSN------------PASAGEQDDFADFMAFGNSSISSEPKASDKYEALREEVSPSPLSS---STVEGAQHPPAAATKYDVFKQLSLEGAGLAMEEFKEN----TSSTKSE-DDFADFHSSKFSSTS--SDKSLGEKAVAFRHAKEDSSSVKSLDLPSIGGSSVGKEDSEDALSVQFDMKLADVGGDLKHVMSDSSLDLPTVSGQHPPAADTEDLSCAAFGSCSSHFTVSTLTSCEWSDRADALQGRKLSPFVLSAGSRSFSATSNLHTKEISFGSSENITMSSLSKGSALASED--ALPETAFPAFASFKDMMPQTTEQKEFESGDFQDFTRQDMPTVDRSQETSCPSPASSVASHETPKEGADDFGEFQSEKSKISKFDFLVANSQSKMKSSEEMIKSELATFDLSVQGSHKRSLSLGDKEISRSSPSPALEQPFRDRSNTLSERAALPVIRDKYKDLTGEVEENERYAYEWQRCLGSALDVIKKANDTLNGISSSAVCTEVIQSAQGMEYLLGVVEVYRVTKRVELGIKATAVCSEKLQQLLKDIDKVWNNLIGFMSLATLTPDENSLDFSSCMLRPGIKNAQELACGVCLLNVDSRSRKEET---------------------------PAEE-----QPKKAFNSETDSFKLAYGGHQYHASCANFWINCVEPKPPGLLLPDLL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0AC58HC52-1", "uniprot_id": "A0AC58HC52_DANRE", "id": "A0AC58HC52-1", "name": "", "aln": "MALRP--------------GSGGGGSFMYPVGGGIGPPQ-GMMPMQQQQQQGFPMVQVMQPNMQGMMGMNFGAQMP-GAMPIQGGMAMG-MQTPGMQFMGQPQFMGMRAPGPQFPADIQKQMAEEHQKRLEQQQRMLEEDRKRRQFEEQKQKLRLLSSVKPKTGEKSRDDALEAIKGNLDGFSRDAKMHPTPSSQSKKPDSSPSHSSVTSHSLPPAFPDDDDEFSDFVQGPVDAFSSFPSPPHPPSSPSLRAAHANQPLETGPGQHPSSTLPHSVPSSLPVSPAIQHSSVISSSQSAFQGPSLEEKMFSSCDLTADKKAQVSFKPRQALSELNPRAQVTAQFHSSTKARNWAQTQDDFHSAFMTGMAPEPLPATQAPPVADNPPIQPTRASGVGAYPQQD-MQPMVPTWLYNDSLIPELFKKVLEFTMTPAGIDTAKLYPILISSGLPREALGQIWALANRTTPGKLTKEELYTVLALIGVAQSGLTVMSLDILSQFPSPPVPNLPAMTMAIPAVLPQHQQPIMTQPPVSMPMPTAAPPVMSMTPN-----PPAQPPATFITNFPPVQATKADDDDFQDFQEAPKAGVGDDSFTDFQGETGGTFPSMTSSSQSSVPAMLTPVSGSSSS-SSDKYAVFKQLSVEQPAEPTPAVSDSGDKYSVFRELEPPSERKPVGEGFADFKSVSADDGFTDFKTADTVSPLDPPDQAKFQPTFPPPFASSQSLSHSQPASLAQPRNPLNMADLDLFT----------TMAPPTSTADSKLNLFPSAPPSLVLPSAVVKPPSMGGDDFGDFALFGSSSSSEVAPTTSAAGRGASTTVQDDFADFMAFGSSRDQRSETSS------REGNSEG-------QTETSQQRHQIGTDKYDVFKQLSLEG-GLAYDDNKESGGGSFSSLKSDNDDFADFQSSKFCTALGASDKSLVDKVAAFKQAKEDSTSVKSLDLPSIGGSSVGKEDSEDALSVQLDMKLSDMGGDLKHVMSDSSLDLPGLSSHQPPAAESDDMKFDPFGTS----TVSSLGSYDWSDKDDLPSGQGKK--LQGGSQGSLPSSAVVQRKETSFGSSENITHTTVAKVTTFPIEDNSSTSESQFEAFADFG-SIEQAGQD---DDDDFGDFASTVSEKSD--------SPPSATEAEGNQGEMTDEFGAFQGDKPKFGKSDFLKASTQAKVKSSEEMIKNELATFDLSVQGSHKRSHSLGEKEIVRSIPSPAPEQPFRDRSNTLNEKPALPIIRDKYKDLTGEVEESERYAYEWQRCLESALQVITTANNTLNGISSSTVCTEVIQSAQGMEYLLGVVEVYRVTKRVELGIKATAVCSEKLQELLKDISRVWNNLMGFMSLANLTPDESSLDFSSCILRHGIKNAKELACGVCLLNVDSRSKKKDENTFGRLFKRALTKDTRSKLRVGCTVCLQSDSNYPFCQLNKAFNSETDNFKLMYGGHQYHASCANFWINCVEPKPPGLILPDLL", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q99PT0-1", "uniprot_id": "DDX52_RAT", "id": "Q99PT0-1", "name": "Probable ATP-dependent RNA helicase DDX52", "aln": "---------------------MDSYDLFRRLGAGAKFDVKRFSADATR----------FQVGKR-----KFGSDSS--------------ETVKGLDFFGN------------------KKSVSDECGGLQTQQELQNEETTEGGLLERSK--------EPKKKKRKKMTADVPAQEDLDGTIQWTSSVEAKLQDKKAN--------------------------------------------------------------------------------------------------------GEKKLTSEKLEHLRKEKINFFR------NKHKIHVQG--------------------TDLPDPIATFQQLDQEYKIS------------------------------------PRLLQNILDAGFQVPTPIQMQAIPVMLHG---------------------------RELLASAPTGSGKTLAFSIPILMQLKQP-------------------------------------------------------------------------------------------------------------------------------------------------------------TNKGFRALVISPTRELASQIHRELIKISEGTGFR----------------------------------------------------------------------------------------IHMIHKAAIAAKKFGPKSSKKFDILVTTPN-------------------------------------------------------------RLIYLLKQEPPGIDLTSVEWLVVDESDKLFEDGKTG--------------FRDQLASIFLACT----SPKVRRAMFSATFAYDVEQWCKLNLDNIVSVSIG---ARNSAVETVEQELLFVGSETGKLLAMRELVKKGFN---------------------------------------------------------PPVLVFVQSIERAKELFHELIYEGIN----------------------------------------------------------------VDVIHAERTQQQRDNTVHSFRAGKIWVLICTALLARG-IDFKGVNLVINYDFPTSSVEYIHRIGRTGRAGN----------------RGKAVTFFTEDDKPLLRSVANVIQQAGCPVPEYIKGFQKLLSKQKKKMIKKPLERESISTT------------PKYFLEQAKQKKVAG-----------QNSKKKETLKGKS--------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .. .:: :..* : . : :* . : ::.:: . . *: ::*: *: ..:. :: **.: :*: .. : *:.: :**. ::.: * . : :*** : :. : .. * ** : * .: : ::.: : . :.. . . :: * :::*: : . : *::: . :** . . .:* * *: . . . ** * .. : .: . :: . . . ** . . .. .* :: .. . . .. * :: . :: * . * * :* * : .. :. * . .*:* .* . *:* :.:: .: :* :*.: :::: .* .. . :: * : .:: : . :. . : : . *:. * . * * ..*. : :*: ::.* .:. *: *: *.:: *: . *::*. : : .* :*: * . . : . :.**:: :*:* .: :*: ..* :: **. . ", "identical_positions": 73, "similar_positions": 218, "identity": "4.88%" }, { "cls_id": "homologset.agr.MGI:1354743", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q923V4-1", "uniprot_id": "FBX6_RAT", "id": "Q923V4-1", "name": "F-box only protein 6", "aln": "-----------------------------------------------MVNINELPENILLELFTHVPAPQLLRNCRLVCSLWRDLIDVMTLWKRKSLREGFVTKDRDEPVDDWKIFYILCSLQRNLLRNPCAEENLRSWRIDSNGGDEWKVESLPGDHGTSFPDTKVKKYFVTSYGMCLKSQMVDLKAEGYSEKLLDTVRPDIVVKDWFAPRADCGCTYHLRVQLASADYIVLASFEPPPVTIEQWNDASWQEISHTFSNYPPGVRHILFQHGGKDTQFWKGWYGPRVTNSSIIVSHRTAKNPAPARTLPEE-----------DTSNRRKILSFGSWEDLSP--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9QZN4-1", "uniprot_id": "FBX6_MOUSE", "id": "Q9QZN4-1", "name": "F-box only protein 6", "aln": "-----------------------------------------------MVHINELPENILLELFIHIPAPQLLRNCRLVCRLWRDLIDVVSLWKRKSLREGFFTKDRCEPVEDWKVFYILCSLQRNLLRNPCAEENLSSWRIDSNGGDRWKVETLPGSCGTSFPDNKVKKYFVTSFEMCLKSQMVDLKAEGYCEELMDTFRPDIVVKDWVAPRADCGCTYQLRVQLASADYIVLASFEPPPVTFQQWNDAKWQEISHTFSDYPPGVRHILFQHGGQDTQFWKGWYGPRVTNSSIIISHRTAKNPPPARTLPEETVVIGRRRRASDSNTHEGFFWQGLWQRLRR--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9NRD1-1", "uniprot_id": "FBX6_HUMAN", "id": "Q9NRD1-1", "name": "F-box only protein 6", "aln": "--------------------------------------MDAPHSKAALDSINELPENILLELFTHVPARQLLLNCRLVCSLWRDLIDLMTLWKRKCLREGFITKDWDQPVADWKIFYFLRSLHRNLLRNPCAEEDMFAWQIDFNGGDRWKVESLPGAHGTDFPDPKVKKYFVTSYEMCLKSQLVDLVAEGYWEELLDTFRPDIVVKDWFAARADCGCTYQLKVQLASADYFVLASFEPPPVTIQQWNNATWTEVSYTFSDYPRGVRYILFQHGGRDTQYWAGWYGPRVTNSSIVVSPKMTRNQASSEAQPGQ-------------KHGQEEAAQSPYRAVVQIF", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AC58IKA2-1", "uniprot_id": "A0AC58IKA2_DANRE", "id": "A0AC58IKA2-1", "name": "", "aln": "MSKSESRHFDSASKEFGHRSDVTWIYKLTLFQRCTFRHDDVIAKGRFSGVMPAVPLAVVEEILLNLPAHQVVRVCRLVCPEWKELVDSAAHWRERCRREGIQPCDASRPPKNWCQFYFITKKRRNLIKNPAADDEFQGWEILENGGNGWEIE----NNRKPFPDNTVTKCFTTSCWLCLKQQLIDLEKEGYNAAFMDQLQPHIKISDWYAPCQDCGSEYNINVELLDDQMKQISDFQPEVVVFEWPNKEPWCQTTHVFKNYGPGVRFIRFTHGGKDTRFWAGNYGIRITNSSVEICPAAEI-------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : :* :: *:: ::** *:: ***** *::*:* : *:.:. ***: . * .* :* **:: . :***::**.*:::: .*.* ***: *::* . *** .*.* *.** :***.*::** *** ::* .:*.* :.** *. ***. *::.*:* . : ::.*:* *.:: *. * : ::.*.:* ***.* * ***:**::* * ** *:****: :. ", "identical_positions": 90, "similar_positions": 83, "identity": "26.16%" }, { "cls_id": "homologset.agr.MGI:1354744", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "F1QSL6-1", "uniprot_id": "F1QSL6_DANRE", "id": "F1QSL6-1", "name": "", "aln": "---------------------------MPRSR-RVKVSHKRQMAHPKTRMGQLDSKHIHTAS------------------GRR----RSDAFTCVVPDVPLAVVEEILLNLPAQQVVQVCRLVCPEWKELVDSSAHWKERCRREGIQPCDASRPPKDWCQFYFITKKRRNLIKNHKADEKFAGWTIVHNGGDNWKSE----ENRKPFPDVTVT---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------KCFVTSYGLCLKQQLIDLQKEGYSAAFMDQVQPHIKISDWYGPRFDCGCKYQICVELLDQKKEPIDTFQPEKVVFEQWNDEPWCQMTHVFKDYGPGVRFISFTHGGRDTQFWAGHYGIRITNSSVEICPAAEKESFPA-------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0AC58IKA2-1", "uniprot_id": "A0AC58IKA2_DANRE", "id": "A0AC58IKA2-1", "name": "", "aln": "---------------------------MSKSESRHFDSASKEFGHRSDVTWIYKLTLFQRCT------------------FRHDDVIAKGRFSGVMPAVPLAVVEEILLNLPAHQVVRVCRLVCPEWKELVDSAAHWRERCRREGIQPCDASRPPKNWCQFYFITKKRRNLIKNPAADDEFQGWEILENGGNGWEIE----NNRKPFPDNTVT---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------KCFTTSCWLCLKQQLIDLEKEGYNAAFMDQLQPHIKISDWYAPCQDCGSEYNINVELLDDQMKQISDFQPEVVVFEWPNKEPWCQTTHVFKNYGPGVRFIRFTHGGKDTRFWAGNYGIRITNSSVEICPAAEI------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8M6YV88-1", "uniprot_id": "A0A8M6YV88_DANRE", "id": "A0A8M6YV88-1", "name": "", "aln": "-----------------------MKRSFSGSPLKARTGGSSESNECLSGMGSFGAASRVSVTRPNAAKEKE----MIEEQAGQGQSDVQCQDSGVQLEIPLDVVEEILLNLPAHQVVRVCRLVCPEWKELVDSAAHWRERCRREGIQPCDASRPPVDWCQFYILNKNRRNLIKNPKAEAGLQGWEIAGNGDACWLTE----ENRKPFPENTVTRCFVSFNGLCLKRQLIDLQKEGYSAAFMDQLQPDIKISDWYTTNTHYKNLYQVNMQLLDEEMQAITSYHPYKMFLEGDNYPWCEITHVFRNYGPGVRFIRFTHGGLGKQTPRGHNGIRLTNSSVEICPAAERLRCTKSNLLINPSAKDGLQGWKMVHSGSGCWVTAENSKPLTDTVTRCFVTSFGLCLKRQLIDLQKEGYSDTFMDQVQPHIKISDWYAPRNDCGSEYQICVELLDQEKKPISTFEPEKVLFHFGNSQPWCQTAHVFKNYGAGVRFISFTHGGKDTHNWAGHYGIIVTNSSVEICPDDESSRFINRNLIKNPSAQAGLQQWELVANGGHQWTTEGNIPTFPVNTCFATSHGLCLKQQLIDLQKEGYSDMFMDQRQPHIKISDWYAPRSDHRSEYQICVELLDQKMNPVCAFQPEKVFFPKGGVYPWRQMSHVFKEYGPGVRFIRFTHGGKNAKFRTDCNGIQVTNSCVEICPVD", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q8BK26-1", "uniprot_id": "FBX44_MOUSE", "id": "Q8BK26-1", "name": "F-box only protein 44", "aln": "------------------------------------------------------------------------------------------MAVGNINELPENILLELFIHIPARQLLLRCRPVCSLWRDLIDLVTLWKRKCLQEGFITEDWDQPVADWKIFYFLRSLQRNLLHNPCAEEGFEFWSLDVNGGDEWKVEDLSKDQRKEFPNDQVK---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------KYFVTSYYTCLKSQVVDLKAEGYWEELMDTTRPDIEVKDWFAARPDCGSKYQLCVQLLSSAHAPLGTFQPDPVMIQQKSDAKWSEVSHTFSNYPPGVRYIWFQHGGVDTHYWAGWYGPRVTNSSITIGPPLP-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D4A6R1-1", "uniprot_id": "D4A6R1_RAT", "id": "D4A6R1-1", "name": "", "aln": "MSSGRDCALGAVLQRGTLQGAGDSRRGAVRAPAARGLGCSRQVCIPGHASSGRTAPRSGRITQRGGSEVTAGGGAPCVGTETRNRLGTDTMAVGNINELPENILLELFTHIPARQLLLRCRPVCSLWRDLIDLVTLWKRKCLQEGFITEDWDQPVADWKIFYFLRSLQRNLLHNPCAEEGFEFWSLDVNGGDEWKVEDLSKDQRKEFPNDQVK---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------KYFVTSYYTCLKSQVVDLKAEGYWEELMDTTRPDIEVKDWFAARPDCGSKYQLCVQLLSSAHAPLGTFQPDPVMIQQKSDAKWREVSHTFSNYPPGVRYIWFQHGGVDTHYWAGWYGPRVTNSSVIIGPPLP-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9H4M3-1", "uniprot_id": "FBX44_HUMAN", "id": "Q9H4M3-1", "name": "F-box only protein 44", "aln": "------------------------------------------------------------------------------------------MAVGNINELPENILLELFTHVPARQLLLNCRLVCSLWRDLIDLVTLWKRKCLREGFITEDWDQPVADWKIFYFLRSLHRNLLHNPCAEEGFEFWSLDVNGGDEWKVEDLSRDQRKEFPNDQVK---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------KYFVTSYYTCLKSQVVDLKAEGYWEELMDTTRPDIEVKDWFAARPDCGSKYQLCVQLLSSAHAPLGTFQPDPATIQQKSDAKWREVSHTFSNYPPGVRYIWFQHGGVDTHYWAGWYGPRVTNSSITIGPPLP-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :* :: *:: ::**:*:: ** **. *::*:* : *:.:* :**: . * .:* :* **:: . :***::* *: : * : **. * * ::** **: *. : *.** *** *::**: *** :** :*.*::.**:.. ***.:*:: *:**.. :. *:*: . :. .. * : :*.*.:* .***:* * *** **: *** ** :****: * * ", "identical_positions": 88, "similar_positions": 78, "identity": "12.63%" }, { "cls_id": "homologset.agr.MGI:1354755", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8NCQ5-1", "uniprot_id": "FBX15_HUMAN", "id": "Q8NCQ5-1", "name": "F-box only protein 15", "aln": "--------------------------------------------------------------MATGRGRILQQHWLGLQTLRGPSRGGGAARG----RARAFGCRKGPGVKLSAGSAALRCHAGGGQHWESSFSCCSGFLDGMPSEILLKIFSYLDAVSLLCTGCVSRRFYHLANDNFIWIGIYSTAFSPARSNWKFNSVEKIAMSMSFLSVQDKEAGYWKKEYITKQIASVKAALADILKPVNPYTGLPVKTKEALRIFGLGWAIILKEKGGKEYIMEHVDLSINDTSVTVIWYGKKWPCLASLSTLDLCGMTPVFTDWYKTPTKHRLRWHSLIAKYNLSHLTISTMIGCDRLIRIFCLHPGLLVGVWKKEEELAFVMANLHFHHLVERSTLGSATIPYELPPHSPFLDDSPE----YGLHGYQLHVDLHSGGVFYLCGTFRNLFTKRGNIENGHVKLIVIHLKNNREHLPLIGKVGLSWKTDIFDGCIKSCSMMDVTLLDEHGKPFWCFSSPVCLRSPATPSDSSSFLGQTYNVDYVDAEGRVHVELVWIRETEEYLIVNLVLYLSIAKINHWFGTEY", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "D3Z8N7-1", "uniprot_id": "D3Z8N7_RAT", "id": "D3Z8N7-1", "name": "", "aln": "MTGAWERSRARDCPEQRRSKSKGGVHRETQSTHARARSGFCARVRGSAGLLCRSSRRYLWVSMATGRGRMLRPGSFGLQALRGSLHGGGTTWGSAGLAAGRSGFRQGSGVKFARGSSVMTQCARPGQHSEKPSSVCFISLDRMPSEILLNIFSYLDVVSLLCVGCVNRRFYHLTSDNLIWVKIYSTAFSSKRRYWKLTSVEETATCVSLLSVEDKEVGYWKKEYITRQISSLKSALAHIIMPVNPYTGLPVKTKEALRVFGLGWAIILREKNGKEYIMRHADHSVNDTSVTVVWYDKNWPHLATLSTLNLYGVTPLFMDQYLTPDPNSPRWLSLIGKYDLSNLSESTMMGCDGLIRIFCLNPGLLVGLWQKEDNLAFVMANLHFHHLVERSTLGSATLPYMLPPHSPLVDDSPE----YGLQGYQMHIDMHGVGIFYLCSTFRNLFSRRECIENGYVKFVVISLKNNREHLPLIGKVGLAWRTNVFDGFIESCFVVDVTLLDEHRKPFWCVSSPVCMRSPAYPSDGSSFLGNTYYVDYMDKEGGVHAELVWIEETEEYFIVSLALYLSVAKINHWFGTKY", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9QZN0-1", "uniprot_id": "FBX15_MOUSE", "id": "Q9QZN0-1", "name": "F-box only protein 15", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------MPSEILVKILSYLDAVTLVCIGCVSRRFYHLADDNLIWVRKYAAAFRSKRSRWKATSVEETATSLSLLSVWDKEDGYWKKEYITKQISSVRAALTNSLSPVKRRTSLPSKTKESLRISGLGWTIILREASGKEHIMQHSNLSVNDNSVTVFWHDKNWPHVDTLSTLDLYGATPIFMEQYKGPNTSCPRWLSLIEKYDLSNLRKSAMIGCDRHVRVFCVNPGLLVGLWQENGGLAFVMANIHSHGLFERSIMGSDTIPYTLPPDTTFVDNYPDSMTFYGDKGFQLHIDIHGSKTYFLCSTFHNLFCRRAGINNGYVKFLMINLKNNREHLPLVGKVGLEWRTDCLNGRIESCIVVDMTLLDEDKKPIWYVSSPVCLRSACLP----DFPQPAYSFEYMDSVGGVCADLGWFENTDEYFIVRLDIYLSVAKLQQWFGRQ-", "tax_id": 10090, "tax_name": "Mouse" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ******::*:****.*:*:* ***.******:.**:**: *::** . * ** .***: * .:*:*** *** *********:**:*:::**:. : **: *.** ****:**: ****:***:* .***:**.* : *:**.****.*:.*:** : :****:* * **:* : * * ** *** **:**:* *:*:*** :*:**::******:*::: *******:* * *.*** :** *:** ***.:.::*: *: ** :*:*:*:*:*. ::**.**:*** :* *:**:**:::* **********:***** *:*: ::* *:** ::*:*****. **:* .*****:**.. * .* :* .:*:* * * .:* *:.:*:**:** * :***:**:::*** : ", "identical_positions": 234, "similar_positions": 120, "identity": "40.34%" }, { "cls_id": "homologset.agr.MGI:1354756", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D4AEK3-1", "uniprot_id": "D4AEK3_RAT", "id": "D4AEK3-1", "name": "Cysteine-rich motor neuron 1 protein", "aln": "MYLVAGGRGLAGCGHLSVSLLGLLLLLARSGTRALVCLPCDESKCEEPRSCPGSIVQGVCGCCYMCARQRNESCGGAYGLHGACDRGLRCVIRPPLNGDSITEYEVGVCEDEDWDDDQLLGFEPCNENLISGCNIINGRCECSTIRTCNNPFEFPRKDMCLSALKRIEEEKPDCTKARCEVQFSPRCPEDSILIEGYAPPGECCPLPSRCVCDPAGCLRKVCQPGYLNILVSKASGKPGECCDLYECKPVFSVDCSTVECPPVQQAVCPLDSYETQVRLTADGCCTLPARCECLSGLCAFPVCEVGSTPRIVSRGDGTPGKCCDVFECVNETKPACVFNSVEYYDGDMFRMDNCRFCRCQGGVSICFTAQCGELNCERYYVPEGECCPVCEDPIYPFNNPAGCYANGQIRAHGDRWREDDCTFCQCINGEPHCVATACGQSCMHPVKVPGECCPVCEEPTYITIDPPACGELSNCTLKEKDCVYGFKLDHNGCRTCQCKNREERCLALKRACTLDCPFGFLTDVHNCELCQCRPRPKKCRPTICDKFCPLGFLRNKHGCDICRCKKCPELPCSKVCPLGFQEDSHGCLICKCR-EVPTSAGPPVLSGTCLSMDGHHHKNEESWHDGCRECYCHNGKEMCALITCPVPACGNPTIRPGQCCPSCADDFVVQKPELSTPSICHAPGGEYFVEGETWNIDSCTQCTCHSGRVLCETEVCPPLLCQNPSRTQDSCCPQCTEDPLQPSTSHNESVPSYCRNDEGDIFLAAESWKPDVCTSCVCMDSSISCYSESCPSVACERPVLRKGQCCPYCLEDTIPKKVVCHFSGKTYADEERWDIDSCTHCYCLQGQTLCSTVSCPPLPCAEPIKVEGSCCPMCPEMYVPEPTNVPIEKKNHRGEIDLEVPMWPTPSENDIIHLPR-DMGHLQVDYRDNNRLHPSEDSSLDSIVPVVVPIIICLSIIIAFLLINQKKQWIPLLCWYRTPTKPSSLNNQLVSVDCKKGTRVQVDGSQRMLRIAEPDARFSGFYSMQKQNHLQADNFYQTV", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9JLL0-1", "uniprot_id": "CRIM1_MOUSE", "id": "Q9JLL0-1", "name": "Cysteine-rich motor neuron 1 protein", "aln": "MYLVAGGRGLAGCGHLSVSLLGLLLLLARSGTRALVCLPCDESKCEEPRSCPGSIVQGVCGCCYMCARQRNESCGGAYGLHGACDRGLRCVIRPPLNGDSITEYEVGVCEDEDWDDDQLIGFEPCNENLISGCNIINGKCECGTIRTCNNPFEFPRKDMCLSALKRIEEEKPDCSKARCEVRFSPRCPEDSILIEGYAPPGECCPLPSRCVCDPAGCLRKVCQPGYLNILVSKASGKPGECCDLYECKPVFSVDCSTVECPPVQQAVCPLDSYETQVRLTADGCCTLPARCECLSGLCGFPVCEVGSTPRIVSRGDGTPGKCCDVFECVNETKPACVFNSVEYYDGDMFRMDNCRFCRCQGGVSICFTAQCGELNCERYYVPEGECCPVCEDPIYPLNNPAGCYANGQIRAHGDRWREDDCTFCQCINGEPHCVATACGQSCMHPVKVPGECCPVCEEPTYITIDPPACGELSNCSLKEKDCVYGFKLDHNGCRTCQCKIREELCLGLKRACTLDCPFGFLTDVHNCELCQCRPRPKKCRPTMCDKFCPLGFLKNKHGCDICRCKKCPELPCSKICPLGFQQDSHGCLICKCR-EVPPSAGPPVLSGTCLSMDGHHHKNEESWHDGCRECYCHNGKEMCALITCPVPACGNPTIRSGQCCPSCTDDFVVQKPELSTPSICHAPGGEYFVEGETWNIDSCTQCTCHSGRVLCETEVCPPLLCQNPSRTQDSCCPQCTDDPPQPSTSHNESVPSYCRNDEGDIFLAAESWKPDACTSCVCVDSAISCYSESCPSVACERPVLRKGQCCPYCLEDTIPKKVVCHFSGKTYADEERWDIDSCTHCYCLQGQTLCSTVSCPPLPCAEPIKVEGSCCPMCPEMYVPEPTNVPIEKKNHRGEIDLEVPMWPTPSENDIIHLPR-DMGHLQVDYRDNNRLHPGEDSSLDSIVSVVVPIIICLSIIIAFLLINQKKQWVPLLCWYRTPTKPSSLNNQLVSVDCKKGTRVQVDGPQRMLRIAEPDARFSGFYSMQKQNHLQADNFYQTV", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9NZV1-1", "uniprot_id": "CRIM1_HUMAN", "id": "Q9NZV1-1", "name": "Cysteine-rich motor neuron 1 protein", "aln": "MYLVAGDRGLAGCGHLLVSLLGLLLLLARSGTRALVCLPCDESKCEEPRNCPGSIVQGVCGCCYTCASQRNESCGGTFGIYGTCDRGLRCVIRPPLNGDSLTEYEAGVCEDENWTDDQLLGFKPCNENLIAGCNIINGKCECNTIRTCSNPFEFPSQDMCLSALKRIEEEKPDCSKARCEVQFSPRCPEDSVLIEGYAPPGECCPLPSRCVCNPAGCLRKVCQPGNLNILVSKASGKPGECCDLYECKPVFGVDCRTVECPPVQQTACPPDSYETQVRLTADGCCTLPTRCECLSGLCGFPVCEVGSTPRIVSRGDGTPGKCCDVFECVNDTKPACVFNNVEYYDGDMFRMDNCRFCRCQGGVAICFTAQCGEINCERYYVPEGECCPVCEDPVYPFNNPAGCYANGLILAHGDRWREDDCTFCQCVNGERHCVATVCGQTCTNPVKVPGECCPVCEEPTIITVDPPACGELSNCTLTGKDCINGFKRDHNGCRTCQCINTEELCSERKQGCTLNCPFGFLTDAQNCEICECRPRPKKCRPIICDKYCPLGLLKNKHGCDICRCKKCPELSCSKICPLGFQQDSHGCLICKCR-EASASAGPPILSGTCLTVDGHHHKNEESWHDGCRECYCLNGREMCALITCPVPACGNPTIHPGQCCPSCADDFVVQKPELSTPSICHAPGGEYFVEGETWNIDSCTQCTCHSGRVLCETEVCPPLLCQNPSRTQDSCCPQCTDQPFRPSLSRNNSVPNYCKNDEGDIFLAAESWKPDVCTSCICIDSVISCFSESCPSVSCERPVLRKGQCCPYCIEDTIPKKVVCHFSGKAYADEERWDLDSCTHCYCLQGQTLCSTVSCPPLPCVEPINVEGSCCPMCPEMYVPEPTNIPIEKTNHRGEVDLEVPLWPTPSENDIVHLPR-DMGHLQVDYRDN-RLHPSEDSSLDSIASVVVPIIICLSIIIAFLFINQKKQWIPLLCWYRTPTKPSSLNNQLVSVDCKKGTRVQVDSSQRMLRIAEPDARFSGFYSMQKQNHLQADNFYQTV", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q7T3Q2-1", "uniprot_id": "CRIM1_DANRE", "id": "Q7T3Q2-1", "name": "Cysteine-rich motor neuron 1 protein", "aln": "---MASSRMYLLVKCMLI--LQLMVLIAKN-SRALICLPCDKSKCEEPKPCTGSVVLGICGCCSVCAKQKNESCGGVYGLYGTCDRGLRCVIRPPLNGGSITQYEVGNCEDENWDDDQLLGFEPCNENLVTGCNIIDGKCECDSVRTCNNPFEFASQEACQTALQKIEEERPDCSKARCEVQFSPRCPEDSILIEGYAPPGECCPLPSRCVCSPAGCLRKVCQPGHLNILVSKSSGKPGECCDLYECKPVFSVDCSTVECPPVKPVQCPADSYETQVRLTADGCCTLPTRCECLPGLCTFPQCSAGMSPQVMSRGDGTPGRCCDVFECVNETKPACTLNGVEYHDGDMFRMDACRFCRCQGGVSVCFTAQCGVLHCERYYVPDGECCPVCEDPIYPVLSLAGCYVNGQILAHGDHWREDDCTFCQCVSGDARCVAAACGHSCLNPVTVPGECCPVCEEPTYITMAPPACGSLDNCTLLEQSCAFGFRLDPSGCRTCACKSREELCGGLMASCTLKCPFGFQTDIHGCDVCQCRPRHKKCKAVACAKDCPFGYIKNKHGCDTCRCKKCPELPCDKACPMGFQHDELGCLICQCRDQSSSSVTPAVKLGSCLSMDGRRHENGQSWHDGCRDCYCHAGREMCALISCPVPPCDNPTIRPGHCCPTCPEESSSHKPELSEASVCLAPGGEYFVEGETWNIDSCTQCTCHSGRVLCETEVCPPLLCHSPIRTQDSCCPHCPDDPVTPQTPSNDSMPSYCRNEDGDIFLAAESWKPNVCSSCVCLDGAISCFSESCPPVNCARPVLRKGQCCPYCLDATP--RAVCHFNGKTYMDEERWDIDSCTHCYCLQGQTLCSTVSCPALPCHQPLTVEGSCCPMCPESYA--PTNVPIEKTDQRGDKSRHQPAWPTHSENDVMPQFRGEFGSLQMPYLDGKTPLPSEDAGLH-WAWVALPVLMMMLTLAALLLVNQRKQWIPVPC-YRTPNKSTCLNNQLVYVDCQKGTKVQVDSSQRMLRIADPDSRYSGYYSMQKHNNLQADNFYQTA", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :*..* : : * *::*:*:. :***:*****:******: *.**:* *:**** ** *:******.:*::*:***************.*:*:**.* ****:* ****:**:******::*****:*:***.::***.*****. :: * :**::****:***:******:*********:********************.************ *******:*****************.*** *******: . ** ******************:*****.*** ** *..* :*:::********:*********:*****.:*.***:******** **********::******* ::*******:**********:**. . ****.** * ****:***********:.*: :***:.**::* :**.************* **: *****.*.**:* :.* **: * .***** * ** * .***.***** ** :.*::*:**** ***:. * * **:* ::****** *********.*.* **:***.*. *****:** : ..*. *.: *:**::**::*:* :*******:*** *:******:****.*.****:.*:***:*.:: :***** .*:* ****************************************:.* ********:*.::* *. . *:*:*.**:*::************:.*:**:*:*. ***:*****.* * *************:: * :.****.**:* ******:*********************.*** :*:.*********** *. ***:****.::**: . . * *** ****:: * ::* **: * *. *.**:.*. . *.:*::: : : *:*::**:***:*: * ****.*.:.****** ***:***:****..*******:**:*:**:*****:*:*********.", "identical_positions": 692, "similar_positions": 221, "identity": "66.6%" }, { "cls_id": "homologset.agr.MGI:1354757", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P98195-1", "uniprot_id": "ATP9B_MOUSE", "id": "P98195-1", "name": "Probable phospholipid-transporting ATPase IIB", "aln": "MADQ-IPLY------------------PVRSAG-AAASHRR---------------------------------AAYYSSAGPGPGADRRGRYQLE-----DES------AHLDEMPLMMS----------------------------------EEGFENDESDYHTLPRARITRRKRGLEWFVCGGWKFLCT--------SCCDWLINVCQRK----KELKARTVWLGCPEKCEEKHPRN-----SIKNQKYNVFTFIPGVLYEQFKFFLNLYFLVVSCSQFVPALKIGYLYTYWAPLGFVLAVTIAREAIDEFRRFQRDKEMNSQLYSKLT---VRGKVQVKSSDIQVGDLIIVEKNQRIPSDMVFLRTSEKAGSCFIRTDQLDGETDWKLKVAVSCTQRLPALGDLFSISAYVYAQKPQLDIHSFEGTFTREDSDPPIHESLSIENTLWASTIVAS-GTVIGVVIYTGKETRSVMNTSNPNNKVGLLDLELNQLTKALFLALVVLSVVMVTLQGFAG-PWYRNLFRFLLLFSYIIPISLRVNLDMGKAAYGWMIMKDENIPGTVVRTSTIPEELGRLVYLLTDKTGTLTQNEMVFKRLHLGTVSYGTDTMDEIQSHVLNSYLQVHS-QPSGHNPSSAP--LRRSQSSTPKVKKSVSSRIHEAVKAIALCHNVTPVYEARA--GITGETEFAEADQD------------FSDENRTYQASSPDEVALVRWTESVGLTLVSRDL--ASMQLKTPSGQ---VLTYCILQMFPFTSESKRMGIIVRDESTAEITFYMKGADVAMSTIVQYNDWLEEECGNMAREGLRTLVVAKRTLTEEQYQDFESRYSQAKLSIHDRALKVAAVVES-LEREMELLCLTGVEDQLQADVRPTLEMLRNAGIKIWMLTGDKLETATCIAKSSHLVSRTQDIHVFRPVTSRGEAHLELNAFRRKHDCALVISGDSLEVCLRYYEHELVELACQCPAVVCCRCSPTQKAHIVTLLRQHTRKRTCAIGDGGNDVSMIQAADCGIGIEGKEGKQASLAADFSITQFRHIGRLLMVHGRNSYKRSAALGQFVMHRGLIISTMQAVFSSVFYFASVPLYQGFLMVGYATIYTMFPVFSLVLDQDVKPEMAILYPELYKDLTKGRSLSFKTFLIWVLISIYQGGILMYG---ALLLFEDEFVHVVAISFTALILTELLMVALTIRTWHWLMVVAEFLSLGCYVASLAFLNEYFGIGRVSFGAFLDVAFITTVTFLWKVSAITVVSCLPLYVLKYLKRKLSPPSYSKLSS----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D4ABB8-1", "uniprot_id": "ATP9B_RAT", "id": "D4ABB8-1", "name": "Probable phospholipid-transporting ATPase IIB", "aln": "MADQ-IPLY------------------PVRSAAAAAASHRR---------------------------------AAYYSAVGPGPGADRRGRYQLE-----DES------AHLDEMPLMMS----------------------------------EEGFENDESDYHTLPRARITRRERGLEWFVCGGWKFLCT--------SCCDWLINVCQRK----KELKARTVWLGCPEKCEEKHPRN-----SIKNQKYNVFTFIPGVLYEQFKFFLNLYFLVVSCSQFVPALKIGYLYTYWAPLGFVMAVTIAREAIDEFRRFQRDKEMNSQLYSKLT---VRGKVQVKSSDIQVGDLIIVEKNQRIPSDMVFLRTSEKAGSCFIRTDQLDGETDWKLKVAVSCTQRLPALGDLFSISAYVYAQKPQLDIHSFEGTFTRDDSDPPIHESLSIENTLWASTIVAS-GTVIGVVIYTGKETRSVMNTSNPKNKVGLLDLELNQLTKALFLALVVLSVVMVTLQGFAG-PWYRNLFRFLLLFSYIIPISLRVNLDMGKAAYGWMIMKDENIPGTVVRTSTIPEELGRLVYLLTDKTGTLTQNEMVFKRLHLGTVSYGTDTMDEIQSHVLNSYLQVHS-QTSGHNPSSAP--LRRSQSSTPKVKKSVSSRIHEAVKAIALCHNVTPVYEART--GITGETEFAEADQD------------FSDENRTYQASSPDEVALVRWTESVGLTLVSRDL--ASMQLKTPSGQ---VLTYCILQMFPFTSESKRMGIIVRDEATAEITFYMKGADVAMSTIVQYNDWLEEECGNMAREGLRTLVVAKRTLTEEQYQDFESRYSQAKLSIHDRTLKVAAVVES-LEREMELLCLTGVEDQLQADVRPTLEMLRNAGIKIWMLTGDKLETATCIAKSSHLVSRTQDIHIFRPVTNRGEAHLELNAFRRKHDCALVISGDSLEVCLRYYEHELVELACQCPAVVCCRCSPTQKAHIVTLLRQHTRKRTCAIGDGGNDVSMIQAADCGIGIEGKEGKQASLAADFSITQFRHIGRLLMVHGRNSYKRSAALGQFVMHRGLIISTMQAVFSSVFYFASVPLYQGFLMVGYATIYTMFPVFSLVLDQDVKPEMAILYPELYKDLTKGRSLSFKTFLIWVLISIYQGGILMYG---ALLLFEAEFVHVVAISFTALILTELLMVALTIRTWHWLMVVAEFLSLGCYVASLAFLNEYFGIGRVSFGAFLDVAFITTVTFLWKVSAITVVSCLPLYVLKYLKRKLSPPSYSKLSS----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O43861-1", "uniprot_id": "ATP9B_HUMAN", "id": "O43861-1", "name": "Probable phospholipid-transporting ATPase IIB", "aln": "MADQ-IPLY------------------PVRSAAAAAANRKR---------------------------------AAYYSAAGPRPGADRHSRYQLE-----DES------AHLDEMPLMMS----------------------------------EEGFENEESDYHTLPRARIMQRKRGLEWFVCDGWKFLCT--------SCCGWLINICRRK----KELKARTVWLGCPEKCEEKHPRN-----SIKNQKYNVFTFIPGVLYEQFKFFLNLYFLVISCSQFVPALKIGYLYTYWAPLGFVLAVTMTREAIDEFRRFQRDKEVNSQLYSKLT---VRGKVQVKSSDIQVGDLIIVEKNQRIPSDMVFLRTSEKAGSCFIRTDQLDGETDWKLKVAVSCTQQLPALGDLFSISAYVYAQKPQMDIHSFEGTFTREDSDPPIHESLSIENTLWASTIVAS-GTVIGVVIYTGKETRSVMNTSNPKNKVGLLDLELNRLTKALFLALVALSIVMVTLQGFVG-PWYRNLFRFLLLFSYIIPISLRVNLDMGKAVYGWMMMKDENIPGTVVRTSTIPEELGRLVYLLTDKTGTLTQNEMIFKRLHLGTVSYGADTMDEIQSHVRDSYSQMQS-QAGGNNTGSTP--LRKAQSSAPKVRKSVSSRIHEAVKAIVLCHNVTPVYESRA--GVTEETEFAEADQD------------FSDENRTYQASSPDEVALVQWTESVGLTLVSRDL--TSMQLKTPSGQ---VLSFCILQLFPFTSESKRMGVIVRDESTAEITFYMKGADVAMSPIVQYNDWLEEECGNMAREGLRTLVVAKKALTEEQYQDFESRYTQAKLSMHDRSLKVAAVVES-LEREMELLCLTGVEDQLQADVRPTLEMLRNAGIKIWMLTGDKLETATCIAKSSHLVSRTQDIHIFRQVTSRGEAHLELNAFRRKHDCALVISGDSLEVCLKYYEHEFVELACQCPAVVCCRCSPTQKARIVTLLQQHTGRRTCAIGDGGNDVSMIQAADCGIGIEGKEGKQASLAADFSITQFRHIGRLLMVHGRNSYKRSAALGQFVMHRGLIISTMQAVFSSVFYFASVPLYQGFLMVGYATIYTMFPVFSLVLDQDVKPEMAMLYPELYKDLTKGRSLSFKTFLIWVLISIYQGGILMYG---ALVLFESEFVHVVAISFTALILTELLMVALTVRTWHWLMVVAEFLSLGCYVSSLAFLNEYFGIGRVSFGAFLDVAFITTVTFLWKVSAITVVSCLPLYVLKYLRRKLSPPSYCKLAS----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F1Q4S1-1", "uniprot_id": "ATP9B_DANRE", "id": "F1Q4S1-1", "name": "Probable phospholipid-transporting ATPase IIB", "aln": "MADG-IPLN------------------PVR------KNLRK---------------------------------TAYYDASRP-------ARYQIE-----DES------SNLDEMPLMMS----------------------------------EEAFENDESDYQTLPRARVSQRRRGLGWFLCGGWKVLCS--------SCCECLVHTCRRK----KELKARTVWLGHPEKCEEKYPKN-----AIKNQKYNIVTFVPGVLYQQFKFFLNLYFLVVACSQFVPSLKIGYLYTYWAPLGFVLAVTMVREAVDEVRRCRRDKEMNSQLYSKLT---VRGKVQVKSSDIQVGDLIIVEKNQRIPADMIFLRTSEKTGSCFIRTDQLDGETDWKLRIGVACTQRLPALGDLFSISAYVYVQKPQLDIHSFEGNFTREDCDPPIHESLSIENTLWASTVVAS-GTVIGVVIYTGKEMRSVMNTSQSKNKVGLLDLELNRLTKALFLAQVVLSVVMVALQGFLG-PWFRNLFRFVVLFSYIIPISLRVNLDMGKSAYGWMIMKDENIPGTVVRTSTIPEELGRLVYLLTDKTGTLTQNEMVFKRLHLGTVSYGTDTMDEIQSHIIQSYAQVSSAQSNGSSASSTP--SRKPQPPAPKVRKSVSSRIHEAVKAIALCHNVTPVYESRVN-GANAEPESTEADQD------------FSDDNRTYQASSPDEVALVRWTESVGLTLVNRDL--TSLQLKTPAGQ---ILTYYILQIFPFTSESKRMGIIVREEATGDITFYMKGADVAMASIVQYNDWLEEECGNMAREGLRTLVVAKKSLTEEQYQDFENRYNQAKLSIHDRNLKVAAVVES-LEREMELLCLTGVEDQLQADVRPTLELLRNAGIKIWMLTGDKLETATCIAKSSHLVSRNQDIHVFKPVSNRGEAHLELNAFRRKHDCALVISGDSLEVCLRYYEHEFVELACQCPAVVCCRCSPTQKAQIVRLLQQHTANRTCAIGDGGNDVSMIQAADCGIGIEGKEGKQASLAADFSITQFKHIGRLLMVHGRNSYKRSAALGQFVMHRGMIISTMQAVFSSIFYFASVPLYQGFLMVGYATIYTMFPVFSLVLDQDVKPEMALLYPELYKDLTKGRSLSFKTFLIWVLISIYQGGILMYG---ALVLFDQEFVHVVAISFTALILTELLMVALTIRTWHWLMVVAQLISLACYLASLAFLNEYF-----------DLSFITTRVFLWKVCVITLVSCLPLYIIKYLKRKFSPPSYSKLSS----", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VK06-1", "uniprot_id": "Q9VK06_DROME", "id": "Q9VK06-1", "name": "Phospholipid-transporting ATPase", "aln": "MAESNVPLRDFDEESETDSETELLIRRDVPSGKQNNNNIRGRRKSSMGYSGVDAGAGSSAAGGGGSFLGNLFGSNSFGSAAGQIRYRNERSRERAK-----HSNGSYSSISKLAQLTHTSSGVAGAGSIGGGGGGSGSATGIKVTTGDGSVAASGGSAATGDLSNGATHSTTVIDPENGSSTVFYQHNRRKSKSR----SIGNVCKLCLCSCWRKWFRPRELRARTVNLGRVN--TEKFPPN-----EIRNQKYNFITFLPLVLFEQFRFFLNLYFLLMALSQFIPDIRIGYPYTYWGPLGFVLMVTICREAVDDLRRHQRDHEVNSQKYKRLSSTNISGYEMVPSSKLKVGDVIIVEKNERVPADLILLRTSDRSGSVFVRTDQLDGETDWKPRLAVPYTQKLSRDSELHSIDASFYVEKPQNDIHSFIATFCMADGSE--DTGLSVENTLWANTVVAA-GTATGIVIYTGCETRSVMNNSQPRSKVGLLDMEINGLTKVLFCAVLGLSLVMMMLKGFGG-PWYRYMFRFVLLFSYIIPISLRVNLDMGKAFYSWQMQNDSNIQGTVVRSTTIPEELGRISYVLTDKTGTLTQNEMVFKKIHLGIVSHDADTFHHIGQMIQKLSGNILQQQQGSLSSSSSGGDSTKPMMFGNRMRRPEGWREWEAVRALALCHNVTPVSDDEDNRSVSTASTVTGGNNSPTKSVINIEAPGSTDTEHQYQAASPDEIALVKWTEQVGLTLIARDLNTMTLQVKTPSEDNDILLHYQILQLFPFTSESKRMGIIVRESKTGQITFYLKGADVVMSSIVQYNDWLSEESGNMAREGLRTLVVAKKVLTEEQYSDFETRYNAARLSITDRVAKVAAVTES-LERELELLCLTGVEDRLQENVRPTLELLRNAGVRVWMLTGDKLETACCIAKSSQLIGRNQGLHVLRSVKTRTDAHQELNSFRRKQGHALVISGESLEVCLQYYRPEFLELATASPAVVCCRCSPTQKAQVVALIQKHTGKRTCAVGDGGNDVSMIQQADAGVGIEGREGRQASLAGDFSIPQFSHIAKLLLIHGRRSYKRSAALSQFVIHRGLIITTLQAVFSAVFYLSSVALYQGFLMVGYSTLYTMFPVFSLVLDQDITSETAVTYPELYKDLSKGRSLSYKTFFIWVLISIYQGGVIMYG---ALILFVDEFIHIVAISFSALIMTELIMVALTVRTWHRLMVLAELFSLALYLISLAVLHEYF-----------DWEFIWSYDFLWKVSLITLVSCLPLYIIKFLRKKCSPPSYLKLS-----", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P40527-1", "uniprot_id": "ATC7_YEAST", "id": "P40527-1", "name": "Phospholipid-transporting ATPase NEO1", "aln": "MPNP-PSFKS-----------------HKQNLFNSNNNQHAN----------------------SVDSFDLHLDDSFDAALDSLQINNNPEPLSKHNTVGDRESFEMRTVDDLDNFSNHSS----------------------------------DSHRKSSNTDTHPLMYDNRLSQDDNFKFTNIASSPPSSSNNIFSKALSYLKVSNTKNWSKFGSPIELSDQHIEREIHPDTTPVYDRNRYVSNELSNAKYNAVTFVPTLLYEQFKFFYNLYFLVVALSQAVPALRIGYLSSYIVPLAFVLTVTMAKEAIDDIQRRRRDRESNNELYHVIT-----RNRSIPSKDLKVGDLIKVHKGDRIPADLVLLQSSEPSGESFIKTDQLDGETDWKLRVACPLTQNLSENDLINRIS--ITASAPEKSIHKFLGKVTYKDSTS---NPLSVDNTLWANTVLASSGFCIACVVYTGRDTRQAMNTTTAKVKTGLLELEINSISKILCACVFALSILLVAFAGFHNDDWYIDILRYLILFSTIIPVSLRVNLDLAKSVYAHQIEHDKTIPETIVRTSTIPEDLGRIEYLLSDKTGTLTQNDMQLKKIHLGTVSYTSETLDIVSDYVQSLVSSKNDSLNNSKVALSTT-------------RKDMSFRVRDMILTLAICHNVTPT---------------------------------FEDDELTYQAASPDEIAIVKFTESVGLSLFKRDRHSISLLHEHSGKT----LNYEILQVFPFNSDSKRMGIIVRDEQLDEYWFMQKGADTVMSKIVESNDWLEEETGNMAREGLRTLVIGRKKLNKKIYEQFQKEYNDASLSMLNRDQQMSQVITKYLEHDLELLGLTGVEDKLQKDVKSSIELLRNAGIKIWMLTGDKVETARCVSISAKLISRGQYVHTITKVTRPEGAFNQLEYLKINRNACLLIDGESLGMFLKHYEQEFFDVVVHLPTVIACRCTPQQKADVALVIRKMTGKRVCCIGDGGNDVSMIQCADVGVGIVGKEGKQASLAADFSITQFCHLTELLLWHGRNSYKRSAKLAQFVMHRGLIIAICQAVYSICSLFEPIALYQGWLMVGYATCYTMAPVFSLTLDHDIEESLTKIYPELYKELTEGKSLSYKTFFVWVLLSLFQGSVIQLFSQAFTSLLDTDFTRMVAISFTALVVNELIMVALEIYTWNKTMLVTEIATLLFYIVSVPFLGDYF-----------DLGYMTTVNYYAGLLVILLISIFPVWTAKAIYRRLHPPSYAKVQEFATP", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus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identical_positions": 423, "similar_positions": 355, "identity": "32.64%" }, { "cls_id": "homologset.agr.MGI:1354758", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q6L8G5-1", "uniprot_id": "KR510_HUMAN", "id": "Q6L8G5-1", "name": "Keratin-associated protein 5-10", "aln": "MGCCGCSGGCGSGCGGCG----------------SGCGGCGSGCGGYGSG----------------CGGCGSSCCVPVCCCKPVCCCVPACS-CSSCGSCGGSKGDCGSCGGSKGGCGSCGGSKGGCGSCGGSKGGCGSCGGS---KGGCGSCGGSKGGCGS-CGGSKGGCGSCG--CSQCNCCKPCCCSS---------GCG-SCCQSSCCNPCCCQSSCCVPVCC----------QSSCCKPCCCQSSCCVPVCCQCKI", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q701N4-1", "uniprot_id": "KRA52_HUMAN", "id": "Q701N4-1", "name": "Keratin-associated protein 5-2", "aln": "MGCCGCSRGCGSGCGGCG----------------SSCGGCGSGCGGCGSGRGGCGSG--CGGCSSSCGGCGSRCYVPVCCCKPVCSWVPACS-CTSCG----------------------------------------SCGGS---KGGCGSCGGSKGGCGS-CGGSKGGCGSCG--CSQSSCCKPCCCSS---------GCGSSCCQSSCCKPCCCQSSCCVPVCC----------QSSCCKPCCCQSNCCVPVCCQCKI", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6L8G8-1", "uniprot_id": "KRA57_HUMAN", "id": "Q6L8G8-1", "name": "Keratin-associated protein 5-7", "aln": "MGCCGCSEGCGSGCGGCG----------------SGCGGCGSGCG-----------------------GCGSSCCVPVCCCKPVCCCVPACS-CSSCG----------------------------------------SCGGS---KGGCGSCGGSKGGCGS-CGGSKGGCGSCG--CSQCSCYKPCCCSS---------GCGSSCCQSSCCKPCCCQSSCCKPCCCSSGCGS-SCCQSSCCNPCCSQSSCCVPVCCQCKI", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q62220-1", "uniprot_id": "KRA54_MOUSE", "id": "Q62220-1", "name": "Keratin-associated protein 5-4", "aln": "MTCCGCSGGCGSSCGGCGSSCCKPVCCCVPVCSCSSCGGCKGGCGSCGGCKGGCGSCGGCKGGCGSCGGCKGGCCQ-SSCCKPCCCQSSCCKPCCSSGCG-------------------------------------SSCCQSSCCKPCCCQSSCCKPCCSSGCGSSCCQSSCCKPCCCQSSCCKPCCCQSSCCKPCCSSGCGSSCCQSSCCKPCCCQSSCCKPCCCQSSCCKPCCCQSSCCKPCCCQSSCCAPVCCQCKI", "tax_id": 10090, "tax_name": "Mouse" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* ***** ****.***** *.**** .*** ** . * .**** *. ..*. * *.* ** * * * ... .* *.* **.* ...* *.*..* *****.* *** ********:********* * ** *****:***.**.**.********", "identical_positions": 99, "similar_positions": 28, "identity": "37.93%" }, { "cls_id": "homologset.agr.MGI:1354910", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9QX78-1", "uniprot_id": "SOCS1_RAT", "id": "Q9QX78-1", "name": "Suppressor of cytokine signaling 1", "aln": "MVARNQVAADNAISPASEPRRRPEPSSSSSSSSPAAPRRPRPCPVVPAPAPGDTHFRTFRSHSDYRRITRTSALLDACGFYWGPLSVHGAHERLRAEPVGTFLVRDSRQRNCFFALSVKMASGPTSIRVHFQAGRFHLDGSRETFDCLFELLEHYVAAPRRMLGAPLRQRRVRPLQELCRQRIVAAVGRENLARIPLNPVLRDYLSSFPFQI", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O35716-1", "uniprot_id": "SOCS1_MOUSE", "id": "O35716-1", "name": "Suppressor of cytokine signaling 1", "aln": "MVARNQVAADNAISPAAEPRRRSEPSSSSSSSSPAAPVRPRPCPAVPAPAPGDTHFRTFRSHSDYRRITRTSALLDACGFYWGPLSVHGAHERLRAEPVGTFLVRDSRQRNCFFALSVKMASGPTSIRVHFQAGRFHLDGSRETFDCLFELLEHYVAAPRRMLGAPLRQRRVRPLQELCRQRIVAAVGRENLARIPLNPVLRDYLSSFPFQI", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O15524-1", "uniprot_id": "SOCS1_HUMAN", "id": "O15524-1", "name": "Suppressor of cytokine signaling 1", "aln": "MVAHNQVAADNAVSTAAEPRRRPEPSSSSSSS-PAAPARPRPCPAVPAPAPGDTHFRTFRSHADYRRITRASALLDACGFYWGPLSVHGAHERLRAEPVGTFLVRDSRQRNCFFALSVKMASGPTSIRVHFQAGRFHLDGSRESFDCLFELLEHYVAAPRRMLGAPLRQRRVRPLQELCRQRIVATVGRENLARIPLNPVLRDYLSSFPFQI", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "***:********:*.*:*****.********* **** ******.*****************:*******:************************************************************************:*****************************************:**************************", "identical_positions": 200, "similar_positions": 10, "identity": "94.34%" }, { "cls_id": "homologset.agr.MGI:1354944", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9JK30-1", "uniprot_id": "ORC3_MOUSE", "id": "Q9JK30-1", "name": "Origin recognition complex subunit 3", "aln": "MHTGPRTMATSSVSKGCFVFKPDFKKRKVFVPIEDYFNNEELDSEDSKLRFETYSLLWQRMKSETEQLQEELNENLFDNLVDFLQKSHPEFQKNSRDWGSQMKFREIPTAALILGVNVTDHDVILRSLTETLQNNVTPYVVSLQAKDCPDVKHFLQKFTSQLMDCCVDRHSKEV-TSGKALKKTNYSMDSLCSWYSAVTQKADHKVTIKKRTASGHWRSPPVVLILKSMESFTSKVLQDFITISS--QHLHEFPLILIFGIATSPVIIHRLLPHSVSSLLCVELFQSLSCE----QHLTVVLDKLLLTPQFPFKLSKKALQVLTNIFLY-HDFSIQSFIKGIKLSLLEHFYSQPLSVLCCDLSEAKKRVNVFSVSQCENIRRLPSFRRYVENQPLGKQVALLTNETFLKEKTQSLLEDLHVYHINYFLVLRCLHNFTSSLPKYPLGRQIRELYCTCLEKKIWDSEEYKSALQLLRMLAKDELVSILQRCIEVLDSSTEKQLGNTTQKIKDFLTQFQNLDADSKEEEDACGSQP---KGLQKTDLYHLQKSLLEMKELRR-TKKPTKFEMLRENVMNFIDNLVRDYLLPPESQPLHEVVYFSAANTLREHLNAAPRIALHTALNNPYYYLKNEEL---EGCIPNTAPDICIAYKLHLECSLLINLVDWAEAFATVVTAAEKMDANSTVSEEMSEVIHARFIRAVSELELLGFIKPTKQKT-DHVARLTWGGC", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q4R180-1", "uniprot_id": "ORC3_RAT", "id": "Q4R180-1", "name": "Origin recognition complex subunit 3", "aln": "-------MATSSVSKGCFVFKPDFKKRKISVPIEDYFNNEELDSEDSKLRFETYRLLWQRIKSETEQLQEGLNENLFDNLVDFLQKSHSEFQKNSGNWGSQMRLREIPTAALILGVNVTDHDVIFRSLTETLHNNVTPYVVSLQAKDCPDVKHFLQKLTSELIDCCVDRNSKEE-KNDKALRRTSYSMDSLSSWYSTVAQKTGPKMTSKKRATCSQWQSPPVVLILKNMESFSTKVLQDFIIISS--QHLHEFPLILIFGIATSPVIIHRLLPHSVSSLLCIELFQSLSCK----EHLTVVLDKLLLTPQFPFKLSKKALQVLTNIFLY-HDFSIQNFIKGLKLSLLEHFYSQPLSVLCCDLSEAKKRINVFSVNQCEKIRRLPSFRRYVENQPLEKQVALLTNETFLKEETQSLLEDLHVYHINYFLVLRCLHNFTSSLPKYPLGRQIRELYCTCLEKKIWDSEEYESALQLLRMLAKDELMGILEQCVKVLNSSTEKQLSNTAQKIKGFLTQFQNLD-DSKEEEDACGSQP---KGLQKTDLYHLQKSLLEMKELRRTTKKPTKFEMLRENVINFIDNLVRDYLLPPEGQPLHEVVYFSAANTLREHLNAAPRIALHTALNNPYYYLKNEALKSEEGCIPSVAPDICIAYKLHLECSRLINLVDWSEAFATVVTAAEKMDTNSTVSEEMSEIIHARFIRAVSELELLGFIKPTKQKT-DHVARLTWGGC", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9UBD5-1", "uniprot_id": "ORC3_HUMAN", "id": "Q9UBD5-1", "name": "Origin recognition complex subunit 3", "aln": "-------MATSSMSKGCFVFKPNSKKRKISLPIEDYFNKGKNEPEDSKLRFETYQLIWQQMKSENERLQEELNKNLFDNLIEFLQKSHSGFQKNSRDLGGQIKLREIPTAALVLGVNVTDHDLTFGSLTEALQNNVTPYVVSLQAKDCPDMKHFLQKLISQLMDCCVDIKSKEEESVHVTQRKTHYSMDSLSSWYMTVTQKTDPKMLSKKRTTSSQWQSPPVVVILKDMESFATKVLQDFIIISS--QHLHEFPLILIFGIATSPIIIHRLLPHAVSSLLCIELFQSLSCK----EHLTTVLDKLLLTTQFPFKINEKVLQVLTNIFLY-HDFSVQNFIKGLQLSLLEHFYSQPLSVLCCNLPEAKRRINFLSNNQCENIRRLPSFRRYVEKQASEKQVALLTNERYLKEETQLLLENLHVYHMNYFLVLRCLHKFTSSLPKYPLGRQIRELYCTCLEKNIWDSEEYASVLQLLRMLAKDELMTILEKCFKVFKSYCENHLGSTAKRIEEFLAQFQSLD-ETKEEEDASGSQP---KGLQKTDLYHLQKSLLEMKELRR-SKKQTKFEVLRENVVNFIDCLVREYLLPPETQPLHEVVYFSAAHALREHLNAAPRIALHTALNNPYYYLKNEALKSEEGCIPNIAPDICIAYKLHLECSRLINLVDWSEAFATVVTAAEKMDANSATSEEMNEIIHARFIRAVSELELLGFIKPTKQKT-DHVARLTWGGC", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F1QP75-1", "uniprot_id": "F1QP75_DANRE", "id": "F1QP75-1", "name": "Origin recognition complex subunit 3", "aln": "---MNETLTTSSVSKGCFVFKSASKKRKRHVGLDEYLVEADDDS--GRDRFRICQKLWETVQTSTEEIQNQLNKKVLDSLVEFIKK--HELGSSSDVWR--QRTSEIPTAALMLGVNVPDHAMTFRSLCNLLQDSVTPFVVSVHAKECAAVKHLIQKVLEQLMGKAVSVDEEQE-EDAALPQKAQCTISALCQWYKTATKKCS-----QKKNDNGLRQSLPVVVIFKDFEAFNSQVLQDFIHICS--RYIQELPFIFVFGIATSPSAIQHRLPHSVSSLLCIEVFQSVSCT----QHLASVFDKLILNAHFPFKLSSRVIQVLVGIFLY-HDFSVQNFVKGLQFSMLEHFNSQPLSVLCCRKREALLCAKTLSQQNVERIRHLPSFMRYVETQEPEEQVKLLTSDQHVKEVCQTLLKSLHKYHKNYFPILQCLHSLTSSLPKFPLGKHIRELHVSCNEKNLWETEEYDSAMQLLRILAKNELVAALQGCSDILQSASTKRMQTVFQQVEDFINRLETLESVSSEDSSVNGAISGKIDYQRKTDLFQLQKTLLE-KESRR-TKKMSPFEVLRSQVIEFIDSLVREYLTPAHLQPLSEVCYFSSSGILRQRLNVTPRTSIQAALSHPYYYLQNESLKTNAGTISSAAPDLCIVYKLHLECGRLINLYDWLEAFVTVLSAAEDQDADSGDHGQLDSLKHARFIQAVSEMEFLGFVKSTKQKT-DHVARLTWGGC", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P54790-1", "uniprot_id": "ORC3_YEAST", "id": "P54790-1", "name": "Origin recognition complex subunit 3", "aln": "-------MSDLNQSKKMNVSEFADAQRSHYTVYPSLPQSNKNDK-----HIPFVKLLSGKESEVNVEKRWELYHQLHSHFHDQVDHIIDNIEADLKAEISDLLYSETTQKRRCFNTIFLLGSDSTTKIELKDESSRYNVLIELTPKESPNVRMMLRRSMYKLYSAADAEEHPTIKYEDINDEDGDFTEQNNDVSYDLS---------LVENFKRLFGKDLAMVFNFKDVDSINFNTLDNFIILLKSAFKYDHVKISLIFNINTNLSNIEKNLRQSTIRLLKRNYHKLDVSSNKGFKYGNQIFQSFLDTVDGKLNLSDRFVEFILSKMANNTNHNLQLLTKMLDYSLMSYFFQNAFSVFIDPVN-----VDFLNDDYLKILSRCPTFMFFVEG---------LIKQHAPADEILSLLTNKNRGLEEFFVEFLVRENPINGHAKFVARFLEEELNITNFN---------------LIELYHNLLIGKLDSYLDRWSACKEYKDRLHFEPIDTIFQELFTLD---------------------------------------------NRSGLLTQSIFPSYKSNIEDNLLS------WEQVLPSLDKENYDTLSGDLDKIMAPVLGQLFKLYR-------EANMTINIYDFYIAFRETLPKEEILNFIRKDPSNTKLLELAETPDA-------FDKVALILFMQAIFAFENMGLIKFQSTKSYDLVEKCVWRGI", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :: . ** * : :*. . . . : :: : . . . : * .:: . : : :.: : . * . :.. . .: ... ::.: .*:.. :: :::: :* . . . . : . * :. :. .:*. :*..::: :.*::** : . ... : ::*.* *. *.: * ::. ** : .: . :: :::.:: . . :::..: ::.: . : :..:* : * :. *::.:* .:.:**: . :. . : : : *:* :** * .: : ** . : ::* : .. .. .*: .** : : * * :: *: *: . .: : : :. :: .: .*: . :* ..:. . :.: * . * * : *. : ..*.: : : . :. *: *.:: * ::*: : ..:: ** *: :..: *::*: :* :*::* . *: * * : .* * ", "identical_positions": 66, "similar_positions": 227, "identity": "9.03%" }, { "cls_id": "homologset.agr.MGI:1354945", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8M1PDR3-1", "uniprot_id": "A0A8M1PDR3_DANRE", "id": "A0A8M1PDR3-1", "name": "", "aln": "------------------------------------------------------------------------------MSDMGKKKLF-VLVDVMCVVVASLPFVAMT-IASHPYERG----IFCQDESIGYPVKTDTITNVTLAAVTITCTILIICSGEAYLVYSKK------------IHSNSSFNQYVSAIYKVLGAFLFGGAVSQSLTDLAKYTIGRPRPNFLAVCAP------------KVCKG--FVNLN-NCTGN-----PADVTEARLSFYSGHSSFAMYCMLFLAFYVQARLNAKW-ARLLRPTIQFFLVAFAVYVGYTRVSDYKHHWSDVMVGLLQGALIAILTVRFVSNFFK------------------------------VSPSPECSNQENAVNE--ERKP---------SNSYRYSGPV--------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0ACD6B5N7-1", "uniprot_id": "A0ACD6B5N7_DANRE", "id": "A0ACD6B5N7-1", "name": "Phospholipid phosphatase 2", "aln": "------------------------------------------------------------------------------MSELKKNRMFIVLMDLLCVAVVAMPFIIMT-IMYRPYHRG----VYCNDETIQYPYRPDTISHKMMAAVTISCSVIIIISGEAYLVYTKR------------LYSNSDFNQYAAALYKVVGTFLFGACVSQSLTDMAKYTIGRLRPNFMSVCAP------------AVCEG--YMLEI-NCTGN-----ARNVTESRLSFYSGHSSFGMYCMLFLALYVQARLASKW-ARLLRPTIQFFLVAFAIYVGYTRVSDYKHHWSDVVVGLLQGALVAVLTVRYISDFFK------------------------------ERP-PRCPDVENAENADVERKPSLQIADTDRNNYYPISRPV--------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q8K593-1", "uniprot_id": "PLPP2_RAT", "id": "Q8K593-1", "name": "Phospholipid phosphatase 2", "aln": "---------------------------------------------------------------------------------MERRWVF-VLLDVLCVLVASLPFIILT-LVNAPYKRG----FYCGDDSIRYPYRPDTITHGLMAGVIITATVVLVSSGEAYLVYTDR------------LYSRSDFNNYVAAIYKVLGTFLFGAAVSQSLTDLAKYMIGRLRPSFLAVCDPDW--SR------VNCSG--YVQVE-VCRGS-----PANVTEARLSFYSGHSSFGMYCMLFLALYVQARLCWKW-ARLLRPTVQFFLVAFAIYVGYTRVSDNKHHWSDVLVGLLQGALVACLTVCYVSDFFK------------------------------SRPPQSCQ-----ENEESERKPSLSLTLTLGDRP---------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9DAX2-1", "uniprot_id": "PLPP2_MOUSE", "id": "Q9DAX2-1", "name": "Phospholipid phosphatase 2", "aln": "---------------------------------------------------------------------------------MERRWVF-VLLDVLCVLVASLPFIILT-LVNAPYKRG----FYCGDDSIRYPYRPDTITHGLMAGVIITATVILVSLGEAYLVYTDR------------LYSRSNFNNYVAAIYKVLGTFLFGAAVSQSLTDLAKYMIGRLRPSFLAVCDPDW--SQ------VNCSG--YVQLE-VCRGS-----PANVTEARLSFYSGHSSFGMYCMLFLALYVQARLCWKW-ARLLRPTVQFFLVAFAIYVGYTRVSDHKHHWSDVLVGLLQGALVACLTVRYVSDFFK------------------------------SRPPQPCQ-----EDEVPERKPSLSLTLTLGDRP---------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O43688-1", "uniprot_id": "PLPP2_HUMAN", "id": "O43688-1", "name": "Phospholipid phosphatase 2", "aln": "---------------------------------------------------------------------------------MQRRWVF-VLLDVLCLLVASLPFAILT-LVNAPYKRG----FYCGDDSIRYPYRPDTITHGLMAGVTITATVILVSAGEAYLVYTDR------------LYSRSDFNNYVAAVYKVLGTFLFGAAVSQSLTDLAKYMIGRLRPNFLAVCDPDW--SR------VNCSV--YVQLEKVCRGN-----PADVTEARLSFYSGHSSFGMYCMVFLALYVQARLCWKW-ARLLRPTVQFFLVAFALYVGYTRVSDYKHHWSDVLVGLLQGALVAALTVCYISDFFK------------------------------ARPPQHCL-----KEEELERKPSLSLTLTLGEADHNHYGYPHSSS----------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9V576-1", "uniprot_id": "WUN_DROME", "id": "Q9V576-1", "name": "Putative phosphatidate phosphatase", "aln": "MPAVKIIMSTETSASETTPLRRSENETPDHKELAQSNSNSRQTTVNSNNNNYSNSVQVRLQEQDRDSDSEQQQHTATITMDTNKRILCRVGLDVLILLCAGFPILLFF-LLGEPYKRG----FFCDDESLKHPFHDSTVRNWMLYFIGAVIPVGVIFIVEVIISQNKAKQDNGNATSRRYVFMNYELPDWMIECYKKIGIYAFGAVLSQLTTDIAKYSIGRLRPHFIAVCQPQM--ADGSTCDDAINAG--KYIQEFTCKGVG--SSARMLKEMRLSFPSGHSSFTFFAMVYLALYLQARMTWRG-SKLLRHLLQFLFIMVAWYTALSRVSDYKHHWSDVLAGSLIGSISALVVANYVSDLFQ------------------------------KPNTKPYLAR---TVQDMNASPAQAITITTN------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VNU2-1", "uniprot_id": "Q9VNU2_DROME", "id": "Q9VNU2-1", "name": "", "aln": "---------------------------------------------------------------------------------------------------------------MHTFKRG----FFCSDLSIRYPYKDCTITVPMLLLMMLLLPMLFVAVVEIMRICKR-----------------FRTRLYFRNLWRAEATFSFGFIATYLTTELAKHAVGRLRPHFFHGCQPRL--DDGSSCSDLQNAE--LYVEQFHCTNNN--LSTRQIRELHVSFPSAHSSLSFYSMVLLALYVHGVWRGRGGVRVLRHVLQFLLLMAALCVSLSRVADYWHHWSDVLAGALLGVTYAAITAAYVGNLLRRQTSSTGRIPPSLNYSHHLHHQLMADNNNSTASAKVHFLAAAASASMTTTTPLDDIQDSDVEDSRDCRDSEDSHDSQDSHAENEDDNEEVYKSQMSRPVTPPTDLTHVV", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VNT9-1", "uniprot_id": "Q9VNT9_DROME", "id": "Q9VNT9-1", "name": "Phosphatidic acid phosphatase type 2/haloperoxidase domain-containing protein", "aln": "----------------------------------------------------MRDAPEDQSVTVSMPASASGSAAGSTGPSSDRRMTQRLLVELLVVVVLVIPICVYE-FAVDPVRRG----FFCDDESISYPFQDNTITPVMLGLIVGLLPALVMVVVEYVSHLRAGD------ISATVDLLGWRVSTWYVELGRQSTYFCFGLLLTFDATEVGKYTIGRLRPHFLAVCQPQI--ADGSMCSDPVNLH--RYMENYDCAGEG--FTVEDVRQARLSFPSGHSSLAFYAMIYVALYLQRKITWRG-SKLSRHFVQFAVVMVAWYTALSRVMDHWHHWSDVLSGSLLGVAGALITAHYIARMFDDGAS-----------------------NILSGGLRRENTAATLQEEVCPTTPPPYSVNNSFSEDQYCSKV---------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VNU1-1", "uniprot_id": "Q9VNU1_DROME", "id": "Q9VNU1-1", "name": "Phosphatidic acid phosphatase type 2/haloperoxidase domain-containing protein", "aln": "--------------------------------------------------------------------------------MSKYSKLARGFCDLLIWVALSVASVLLH-KMGRPFRRG----FFCGDETLSYPARDGTISSKVIIAIVLGVPNAVIVVVELFRQLPGGP-----LREAGGKRDSCRIAHRLGVLYRQVIFYLYGLAMVTFTTMLTKLCLGRLRPHFLAVCQPML--PDGSSCQDAQNLG--RYIDSFTCSNAN--MTDYQFKELYQSFPSGHASMAMYAMLYLAIYLQAALSTRV-SKLLKHLLQFLFVMFGWYVSLTRIIDYYHHWSDVLAGAALGVVFAWLTSAYVADLFAG----------------------------KRWPKTGYSANTLRKPQVSPKSSTKSQAGGSTSGAGQPPALPAYTFGTLPYLAAHPAQAQAQYAQPYHNYGYVP------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VNT8-1", "uniprot_id": "Q9VNT8_DROME", "id": "Q9VNT8-1", "name": "Phosphatidic acid phosphatase type 2/haloperoxidase domain-containing protein", "aln": "-----------------------------------------------------------------------------MSFNLSLRPPIRLLVDLVLLGLLIVLVENFRRLWGPPTKRG----FFCDDESLMYPYHENTVSPTLLHWLGLYLPLISLVVLESFLSHRKD----------------MAPWPTLWPVYNTVRWFLYGYVSNDLLKGIGKQALGRLRPHFFAVCSPHF--PDGSSCLDESHRGALKYHTDYECRPNLSQATEEMIRDVNVSFPSGHSAMAFYGLVFVALHLRRRRWPLR-GSLLSPVLQLACVALAWFVAISRVIDYKHHWSDVAAGSLLGAGSALAVTRAAASEELQWR---------------------------CQDSLASAKQEAAVVDVADVKGGQQMPHDLSLVTCHISN----------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VNU0-1", "uniprot_id": "Q9VNU0_DROME", "id": "Q9VNU0-1", "name": "Phosphatidic acid phosphatase type 2/haloperoxidase domain-containing protein", "aln": "-----------------------------------------------------------------------------MCGNPNTRLLSRLVIDFLILLGIYGAALVVLPQQLSTAQRG----FHCSDTSLKYPYRQPWLTKVHLTIAVVALPAAFVLVVEMLRAAVVPSS---TELTQRFVFVGVRIPRFISECYKAIGVYLFGLGLTLAAIRLTKHSTGRLRPYFFDICQPTWGTEGGESCSDVTAQNSTLYLEDFSCTEFA--ASQDLLALVRHSFPSGFVSTTCYAMGFLIFYSQARLFAPW-LRLVRASLQLACCSLALVVCWERISTYQNHLTDVAAGAALGGWMAFFATVFVAHLFVEVR---------------------------------------VKRRPMPRNEQIYGYAGYYTRATYGY-----------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q04396-1", "uniprot_id": "LPP1_YEAST", "id": "Q04396-1", "name": "Lipid phosphate phosphatase 1", "aln": "----------------------------------------------------------------------------MISVMADEKHKEYFKLYYFQYMIIGLCTILFLYSEISLVPRGQNIEFSLDDPSISKRYVPNELVGPLECLILSVGLSNMVVFWTCMFDKDLLKK----NRVKRLRERPDGISNDFHFMHTSILCLMLIISINAALTGALKLIIGNLRPDFVDRCIPDL---------QKMSDSDSLVFGLDICKQTN----KWILYEGLKSTPSGHSSFIVSTMGFTYLWQR-VFTTRN------TRSCIWCPLLALVVMVSRVIDHRHHWYDVVSGAVLAFLVIYCCWKWTFTNLA-------------------------------------------KRDILPSPVSV-------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ** . * :: : : * *. ** *. * * * . * *.. : : : : : . . *: :* ** * . ", "identical_positions": 18, "similar_positions": 20, "identity": "3.81%" }, { "cls_id": "homologset.agr.MGI:1354946", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q61532-1", "uniprot_id": "MK06_MOUSE", "id": "Q61532-1", "name": "Mitogen-activated protein kinase 6", "aln": "------------------MAEKFESLMNIHGFDLGSRYMDLKPLGCGGNGLVFSAVDNDCDKRVAIKKIVLTDPQSVKHALREIKIIRRLDHDNIVKVFEILGPSGSQLTDDVGSLTELNSVYIVQEYMETDLANVLEQ-GPLLEEHARLFMYQLLRGLKYIHSANVLHRDLKPANLFINTEDLVLKIGDFGLAR-----IMDPHYSHKGHLSEGLVTKWYRSPRLLLSPNNYTKAIDMWAAGCIFAEMLTGKTLFAGAHELEQMQLILDSIPVVHEEDRQELLSVIPVYIRNDMTEP---HRPLTQLLPGISREALDFLEQILTFSPMDRLTAEEALSHPYMSIYSFPTDEPISSHPFHIEDEVDDILLMDETHSHIYNWERYHDCQFSEHDWPIHNNFDIDEVQLDPRALSDVTDEEEVQVDPRKYLDGDREKYLEDPAFDTSYSAEPCWQYPDHHENKYCDLECSHTCNYKTRSSPYLDNLVWRESEVNHYYEPKLIIDLSNWKEQ-SKEKSDKRGKSKCERNGLVKAQIALEEASQQLA--ERERGQ--------GFDFDSFIAGTIQLSAQHQSADVVDKLNDLNSSVSQLELKS---LISKSVSREKQEKGRANLAQLGALYQSSWDSQFVSGGEECFLISQFCCEVRKDEHAEKENT--YTSYLDKFFSRKEDSEMLETEPVEEGKRGERGREAGLLSGGGEFLLSKQLESIGTPQFHSPVGSPLKSIQATLTPSAMKSSPQIPHKTYSSILKHLN", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P27704-1", "uniprot_id": "MK06_RAT", "id": "P27704-1", "name": "Mitogen-activated protein kinase 6", "aln": "------------------MAEKFESLMNIHGFDLGSRYMDLKPLGCGGNGLVFSAVDNDCDKRVAIKKIVLTDPQSVKHALREIKIIRRLDHDNIVKVFEILGPSGSQLTDDVGSLTELNSVYIVQEYMETDLANVLEQ-GPLLEEHARLFMYQLLRGLKYIHSANVLHRDLKPANLFINTEDLVLKIGDFGLAR-----IMDPHYSHKGHLSEGLVTKWYRSPRLLLSPNNYTKAIDMWAAGCIFAEMLTGKTLFAGAHELEQMQLILESIPVVHEEDRQELLSVIPVYIRNDMTEP---HKPLTQLLPGISREALDFLEQILTFSPMDRLTAEEALSHPYMSIYSFPTDEPISSHPFHIEDEVDDILLMDETHSHIYNWERYHDCQFSEHDWPIHNNFDIDEVQLDPRALSDVTDEEEVQVDPRKYLDGDREKYLEDPAFDTSYSAEPCWQYPDHHENKYCDLECSHTCNYKTRSPSYLDNLVWRESEVNHYYEPKLIIDLSNWKEQ-SKDKSDKRGKSKCERNGLVKAQIALEEASQQLA--ERERGQ--------GFDFDAFIAGTVQLSAQRESADVVDKLNDLNSSVSQLEMKS---LISKSVSREKQEKGRANLAQLGALYQPSWESQFVSGGEECFLISQFCCEVRKDEHVEKENT--YTSYLDKFFSRKEDSEMLETEPVEEGKRGERGREAGLLSSGGEFLLSRQLESIGTPQFHSPGGSPLKSIQATLTPSAMKSSPQIPHKTYSNILKHLN", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q16659-1", "uniprot_id": "MK06_HUMAN", "id": "Q16659-1", "name": "Mitogen-activated protein kinase 6", "aln": "------------------MAEKFESLMNIHGFDLGSRYMDLKPLGCGGNGLVFSAVDNDCDKRVAIKKIVLTDPQSVKHALREIKIIRRLDHDNIVKVFEILGPSGSQLTDDVGSLTELNSVYIVQEYMETDLANVLEQ-GPLLEEHARLFMYQLLRGLKYIHSANVLHRDLKPANLFINTEDLVLKIGDFGLAR-----IMDPHYSHKGHLSEGLVTKWYRSPRLLLSPNNYTKAIDMWAAGCIFAEMLTGKTLFAGAHELEQMQLILESIPVVHEEDRQELLSVIPVYIRNDMTEP---HKPLTQLLPGISREALDFLEQILTFSPMDRLTAEEALSHPYMSIYSFPMDEPISSHPFHIEDEVDDILLMDETHSHIYNWERYHDCQFSEHDWPVHNNFDIDEVQLDPRALSDVTDEEEVQVDPRKYLDGDREKYLEDPAFDTNYSTEPCWQYSDHHENKYCDLECSHTCNYKTRSSSYLDNLVWRESEVNHYYEPKLIIDLSNWKEQ-SKEKSDKKGKSKCERNGLVKAQIALEEASQQLAGKEREKNQ--------GFDFDSFIAGTIQLSSQHEPTDVVDKLNDLNSSVSQLELKS---LISKSVSQEKQEKGMANLAQLEALYQSSWDSQFVSGGEDCFFINQFC-EVRKDEQVEKENT--YTSYLDKFFSRKEDTEMLETEPVEDGKLGERGHEEGFLNNSGEFLFNKQLESIGIPQFHSPVGSPLKSIQATLTPSAMKSSPQIPHQTYSSILKHLN", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AA57WKX4-1", "uniprot_id": "A0AA57WKX4_DANRE", "id": "A0AA57WKX4-1", "name": "Mitogen-activated protein kinase 6", "aln": "------------------MAEKFESLMNIHGFDLGPRYMDLKPLGYGGNGLVFSAVDTDCDKRVAVKKIVLTDPQSVKHALREIKIIRRLDHDNIVKVFETLGPSGRRLTEDVSSLTEVNSVYIVQEYMETDLCKVLEQ-GLLSEDHARLFMYQLLRGLKYIHSANVLHRDLKPANLFVNTEDLVLKIGDFGLAR-----IMDPHYSHKGHLSEGLVTKWYRSPRLLLSPNNYTKAIDMWAAGCIFAEMLTGKTLFAGAHELEQMQLILESIPVVHEEDRLELQSVIPVFIKNDMSEP---HTPLAKLLPGVSPEALDFLEKILTFNPMDRLTAEEALAHPYMSDYSFPLDEPVSLHPFHIEDEVDDILLMDESHSQVYNWDRYHESQFSDQDWHLHSTHELEDVQRDPRALSDVTDEEEVQIDPRKYMDGDCEKFLEDPSFD--LPPEHLWQLEDHHENKYCDQECSYTCNYKAVSPSYLDNLIWRDSEVNHYYEPKLIIDLSNWKEQQSKEKIDKKGKSKCEKNGLVKAQIALKEASQNHTVPEKDRDQEKHQNHNQGFDFDSFIASTIKLSLQPESGD-VDLLNELNTSVSQLDTRAPCGSMSKSISQEKEEKCLVNLAQLGVRAPCPWESFTDCGVAESSLIDQACWDVRKDEQLQKENSSCQSSYLDRLFSKRDDVEPEILEPVEVVS----TTESDFISCSGEIVFNMQLESLAIPGFEGAADIPLKSIQATLAPSAVKHSPQIAHKTYSSIFKHLN", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P41808-1", "uniprot_id": "SMK1_YEAST", "id": "P41808-1", "name": "Sporulation-specific mitogen-activated protein kinase SMK1", "aln": "MNCTLTDNTRAINVASNLGAPQQRTIFAKERISIPGYYEIIQFLGKGAYGTVCSVKFKGRSPAARIAVKKISN-----IFNKEILLKRAIRELKFMNFFKGHKNIVNLIDLEIVTSSPYDGLYCYQELIDYDLAKVIHSSVQLSEFHIKYFLYQILCGLKYIHSADVIHRDLKPGNILCTLNG-CLKICDFGLARGIHAGFFKCHSTVQPHITNYVATRWYRAPELLLSNQPYSKSVDIWAVGCILAEFYARKPVFMGRDSMHQIFEIIKVLGTPDKDILIKFGTIKAWNLGKNSNNPVYKKIPWSNIFPFASHEAINLIESLLHWDSTHRLNVEQAISHPFLNEVRKPDDEPVCLQGPFDFTYESELNSMSKLRDYLVEEVKNFKTDLSSSSL---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * : .::: . :.: * :: ** *. * * *. .. . . : ::: :** : * : . ::::.*: : :: : : :.:* ** :: **.:*:.. * * * : *:**:* ********:*:******.*:: . :. *** ****** ::. * : : *::: :.*:***:*.**** : *:*::*:**.***:**: : *.:* * ..:.*: *:. : . .:: :: :: . : :: .:* : * ::::* * **::::*.:* :.. .**..*:*::**::. * ***:. : . .:: *.: :. : : : .. ::*. . ", "identical_positions": 96, "similar_positions": 146, "identity": "12.58%" }, { "cls_id": "homologset.agr.MGI:1354947", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZYP7-1", "uniprot_id": "D3ZYP7_RAT", "id": "D3ZYP7-1", "name": "DNA polymerase subunit gamma-2", "aln": "MHSGGVARACRRACRCWLSGYAGPTDGTQ--------------------------QPTDPEHALAREALVDLCRRRHFLSGTPQQLSTAALLSGCHSGFGPLGVELRKNLASQWWSSMVVFREQVFAVDSLHHEPGSSQPRDSAFRLVSPECIREILQDKELSKEQLVAFLENLLKTSGKLRETLLHGALEHYVHCLDLVNRKLPYGLAQIGVCFHPVLNPKEIPNSVTRVGEKTEASLVWFTPTRTSSQWLDFWLRHRLLWWRKFAVSPSNFSSVDCQDGSGRKGC----RLYYSFPWGKEPLETLWDLGEQELLNVYPGDVSAIQGRDGRKNVVPSVLSVNGDLDLGTLAYLYDSFQFTENSFSRKKSLQRKVLKLHPCLAPIKVALDVGKGPT---VELRQVCQGLLNELLENGIAVWPG---YLETAQSSLEQLYSKYDEMSILFTVLITETTLESGLIQLRSRDTTMKEMMHISRLRDFLVKYLASAGKA", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9QZM2-1", "uniprot_id": "DPOG2_MOUSE", "id": "Q9QZM2-1", "name": "DNA polymerase subunit gamma-2", "aln": "MRCGGGARACRRACRCWLSGYAGPADGTQ--------------------------QPDAPEHAVAREALVDLCRRRHFFSGTPQQLSTAALLSGCHARFGPLGVELRKNLASQWWSSMVVFREQVFAVDSLHQEPGSSQPRDSAFRLVSPESIREILQDREPSKEQLVAFLENLLKTSGKLRATLLHGALEHYVNCLDLVNRKLPFGLAQIGVCFHPVSNSNQTPSSVTRVGEKTEASLVWFTPTRTSSQWLDFWLRHRLLWWRKFAMSPSNFSSADCQDELGRKGS----KLYYSFPWGKEPIETLWNLGDQELLHTYPGNVSTIQGRDGRKNVVPCVLSVSGDVDLGTLAYLYDSFQLAENSFARKKSLQRKVLKLHPCLAPIKVALDVGKGPT---VELRQVCQGLLNELLENGISVWPG---YSETVHSSLEQLHSKYDEMSVLFSVLVTETTLENGLIQLRSRDTTMKEMMHISKLRDFLVKYLASASNV", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9UHN1-1", "uniprot_id": "DPOG2_HUMAN", "id": "Q9UHN1-1", "name": "DNA polymerase subunit gamma-2", "aln": "MRSRVAVRACHKVCRCLLSGFGGRVDAGQPELLTERSSPKGGHVKSHAELEGNGEHPEAPGSGEGSEALLEICQRRHFLSGSKQQLSRDSLLSGCHPGFGPLGVELRKNLAAEWWTSVVVFREQVFPVDALHHKPGPLLPGDSAFRLVSAETLREILQDKELSKEQLVAFLENVLKTSGKLRENLLHGALEHYVNCLDLVNKRLPYGLAQIGVCFHPVFDTKQIRNGVKSIGEKTEASLVWFTPPRTSNQWLDFWLRHRLQWWRKFAMSPSNFSSSDCQDEEGRKGN----KLYYNFPWGKELIETLWNLGDHELLHMYPGNVSKLHGRDGRKNVVPCVLSVNGDLDRGMLAYLYDSFQLTENSFTRKKNLHRKVLKLHPCLAPIKVALDVGRGPT---LELRQVCQGLFNELLENGISVWPG---YLETMQSSLEQLYSKYDEMSILFTVLVTETTLENGLIHLRSRDTTMKEMMHISKLKDFLIKYISSAKNV", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0ACD6B5J8-1", "uniprot_id": "A0ACD6B5J8_DANRE", "id": "A0ACD6B5J8-1", "name": "", "aln": "-MFFKSTRSCLQRWGESLPLYQRKISKCS----------------------------AHDDSLDQTRLLMRLCSERYYIS--------SEAFNTRTCTYGPLGTELKKNII-DLWTSAIRSRAYVFGISNSMQSRIPEEPG----RIVNLKSFQEILSKDNPSKEETSQNIQKHLKDSLSVRTSLLQGALQQYIQALELVNRTLPFGLAETGLCYN---FDNQLRHSSDCSSEVTESSLVWFCSPRTSSQWMDYWVHHRLKWWRKFALGPSDFNLCNVGDESLKEGASHGVKVLYNFPWGSETLETLWTLGDTQLLKTHQETSVKVQCRDGRKSVVPHVISVSVNVDRGMLAYLFNSLQRLKKTDSKQKLHQRTVLKLHPALTPVKVALDIGRGSN---SELRQVCEGLLQEFLEVGISTWPG---YLDT--KSLENLNTKYDEMGVLFTVMVSESTLKSGLLLVRNRDTTIRETMHISEIKCFLLKYISASENH", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VJV8-1", "uniprot_id": "DPOG2_DROME", "id": "Q9VJV8-1", "name": "DNA polymerase subunit gamma-2, mitochondrial", "aln": "---MSRIQRCFKSLAS--AGFFRTVEDNK---------------------------------------LELLSHGREYAK----------LLQQHWTRLRPLAAHLG---ATKEPINPVNIQRFSFPQSQQFRNN------------------FQKLVKDHPRKAKCPTLLKHQSTCSGPTSNSLFG------------------------------------------IKGPTLHLTTDFLVEPHRALEHFYNMQRESKIWWMRLSSNPSRYRIVPCDLAEDLNPND-YQAIDIRTSYGDAGEVTVEQLS---LVRIVDDKDFRLPDARTGEIVQPTVIRSVIELETTTCALLLDGCDHGRDSQS---------LLLHRVLAPYQCGIACVESDSELSADLSDLCQHLKHVLNHAGLRLSEGDGIRTTKNASHLAEHLLETDMLGIPYTLVINEQTLRNGLMQLRSRDTRLAETIHISDVPDYLLNIFKN----", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : * : . : . . * :. * : . :. **...* . . : : * . :. : * . . * : ::: . * .*: . . : :: .: : : : :. ** ::: .** : : : .:*. *: *. *:. : : * * *: ::: * * :. : ..: : * ** *:* : .: .. . :* ::*: * : : . *: * . . * : : * :.: :::::.* **..**: :*.*** : * :*** : :*:: : ", "identical_positions": 50, "similar_positions": 111, "identity": "10.1%" }, { "cls_id": "homologset.agr.MGI:1354948", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0ABK0M883-1", "uniprot_id": "A0ABK0M883_RAT", "id": "A0ABK0M883-1", "name": "", "aln": "--------------------MAAAAYVDHFAAECLVSMSSRAVVHE-----------PREGPEPRPEGAAAAA-PTLPR---------------------------------VDERRDGKDSASLFVVARILADLNQQAPAPAPAERREGAAARKAR----TPCRLPPAPPAPPPGPEPASPGQAGAPAAPPSPAWSEPE--AALEPE--PGPAGSG--------------------EPGLRQRGRRGRSRADLESPQRK--HKCHYAGCEKVYGKSSHLKAHLRTHTGERPFACSWQECNKKFARSDELARHYRTHTGEKKFSCPICEKRFMRSDHLTKHARRH-------ANFHPGMLQRRGGGSRTGSLSDYSR---------SDASSPTISPASSP----------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9JJZ6-1", "uniprot_id": "KLF13_MOUSE", "id": "Q9JJZ6-1", "name": "Krueppel-like factor 13", "aln": "--------------------MAAAAYVDHFAAECLVSMSSRAVVHE-----------PREGPEPRPEGAAAAA-PTLPR---------------------------------VDERRDGKDSASLFVVARILADLNQQAPAPAPAERREGAAARKAR----TPCRLPPAPPAPPPGPEPASPGQAGAPAAPPSPAWSEPE--AALEQE--PGPAGSG--------------------EPGLRQRGRRGRSRADLESPQRK--HKCHYAGCEKVYGKSSHLKAHLRTHTGERPFACSWQECNKKFARSDELARHYRTHTGEKKFSCPICEKRFMRSDHLTKHARRH-------ANFHPGMLQRRGGGSRTGSLSDYSR---------SDASSPTISPASSP----------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9Y2Y9-1", "uniprot_id": "KLF13_HUMAN", "id": "Q9Y2Y9-1", "name": "Krueppel-like factor 13", "aln": "--------------------MAAAAYVDHFAAECLVSMSSRAVVHG-----------PREGPESRPEGAAVAATPTLPR---------------------------------VEERRDGKDSASLFVVARILADLNQQAPAPAPAERREGAAARKAR----TPCRLP------PPAPEPTSPGAEGAAAAPPSPAWSEPEPEAGLEPEREPGPAGSG--------------------EPGLRQRVRRGRSRADLESPQRK--HKCHYAGCEKVYGKSSHLKAHLRTHTGERPFACSWQDCNKKFARSDELARHYRTHTGEKKFSCPICEKRFMRSDHLTKHARRH-------ANFHPGMLQRRGGGSRTGSLSDYSR---------SDASSPTISPASSP----------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VPQ5-1", "uniprot_id": "Q9VPQ5_DROME", "id": "Q9VPQ5-1", "name": "", "aln": "MDMDTLLPSPPATPPLRENKLEIVAKDEQQVNENLLKAKLKLVAQKSQKNGGIITPNPSDTEDEAPEIAVPNKKPRLEQPAMSMTPPPDQKLDDDQKAERVSVIMRVNSSGAVSSSSQDENSSSSTSCCSSSSNTNTSTSSVPPTVEDDYPEANVWRNLKFKMNRKRAAEVALPPVQTPETPVAKLVTPPAPAECIKEEEIKPILTPIYVSPVASSASQLILLSTVAAQQSPTPVPKTPTMSEEKLTTRITAAQAAATRSRIYECSFPDCGKNYFKSSHLKAHQRVHTGERPFICKWENCDKRFSRSDELSRHKRTHTGEKKFQCSVCQKKFMRSDHLSKHVKRHNKDKANGVNRHVSLANNNTSASVAASLCDASLHLRAIAPAGSSASSSPISSASLQVYSAQDLLRLQQQASSFTFGGTLLQVQR", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : .* :: . * *:. . : *.: * : : ** *. * * : *.. :.::*:* . :: * .:.: .*: . : . *. * . * ** * :* .....*: . .* * . * . *.*. * : :. * * :. *. ::* :..* * * ******** *.******* *.*::*:*:*:*****:** *********.*.:*:*:*******:**.:** .* * .: :.. ..* :.**.* * *.***..**.** ", "identical_positions": 102, "similar_positions": 91, "identity": "23.83%" }, { "cls_id": "homologset.agr.MGI:1354949", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q63744-1", "uniprot_id": "RHG07_RAT", "id": "Q63744-1", "name": "Rho GTPase-activating protein 7", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MCR-----------------------DEPDTMILT--------QIEAKEACDWLRVTG---------FPQYAQLYE-DLLFPIDIALVKREHDFLDRDAIEALCRRLNTLNKCAVMKLEISPHRKRSE---------------------------------------------------------------------------------------------------DSDEEEPCAISGKWTFQRDSKRWSRLEEF--------------------------------DVFSPKQDPIP-----GSPDNSRLQS--------ATSRESMLTDLSEHQEVSSIR-----------SLSSTSSSAPTHVPH-SGEATTPRTNSVISVCSSSHFVGNEDSFSS-LPSPKELSSFSFSMKG------HEKNTKSKTR-----SLLKRMESLKLKGSHHS------------------------------------------------------KHKAPSKLGLIISAPILQEGMDE---------------------------EKLKQLNCVEISALNGNHINVPMVRKRSVSNSTQTSSS----------SSQSETSS--AVSTPSPVTRTRSLSTCN---KRVGMYLEGFDPFSQSAFNN-------------------------------------------------------------------------VTEQNYKN------RESYPEDTVFYIPEDH------------------------------KPGTFPKALSNGSFCPSGNS-SVNWRTGSFHG------------PGHLSLRRENSSD----SPKELKRRNSSSSVSSRMSIYDNVPGS--------------------ILYSSSGELADLENEDIFPELDDILYHVKGMQRIVNQWSEK---------FSDEGDSDSALDSVSPCPSSPKQIHLDVDHDRRTPSDLDSTGNSLNEPEEP----------------------------------------------------------------------------TDIPERRDSGVGASLTRCNR-HRLRWHSFQSSHRP---------------SLNSVSLQINCQSVAQMNLLQKYSLLKLTALLEKYTPSNKHGFSWAVPKFMKRIKVPDYKDRSVFGVPLTVNVQRSGQPLPQSIQQAMRYLRNHCLDQVGLFRKSGVKSRIQALRQMNESAEDY----VNYEGQSAYDVADMLKQYFRDLPEPLMTNKLSETFLQIYQYVPKDQRLQAIKAAIMLLPDENREVLQTLLYFLSHVTAAVKENQMTPTNLAVCLAPSLFHLNTLKRENSSPRVMQRK-QSLGKPDQKDLNENLAATQGLAHMIAECKKLFQVPEEMSRCRNSYTEQELKPLTLEALGHLSNDQPADYRHFLQDCVDGLFKEVKEKFKGWVSYPTS--EQAELSYKKVSEGPPLRLWRATIEVPAAPEEILKRLLKEQHLWDVDLLDSKVIEILDSQTEIYQYVQNSMAPHPARDYVVLRTWRTNLPRGACALLFTSVDHDRAPVAG--VRVNVLLSRYLIEPCGSGKSKLTYMCRADLRGHMPEWYTKSFGHLCAAEVVKIRDSFSNQSTESKDTRSR", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q96QB1-2", "uniprot_id": "RHG07_HUMAN", "id": "Q96QB1-2", "name": "Rho GTPase-activating protein 7", "aln": "-----------------------------------------------------MSVAIRKRSWEEHVTH-WMGQPFNSDDRNTACHHGLVADSLQASM----------EKDATLNVDRKEKCVS------------------------------LPDCCHGSELRDFPGRPMG-HLSKDVDENDSHEGEDQFLSLEASTETLVHVSDEDNNADLCLTDDKQVLN--TQGQKTSGQHMIQGAGSLEKA--LPIIQSNQVSSNSWGIAGETELALVKESGERKVTDS-ISKS---------LELCNEISLSEIKDAPKVN--AVDTLN-----------------VKDIAPEKQLLNSAVIAQQRRKPDPPKDENERSTCN---------------VVQNEFLD-----------------------------------TPCTN-----------RGLPLLKTDFGSCLLQPPSCPNGMSAENGLEKSGFSQHQNKSPPKVKAEDGMQ-------------------------------------------------------------CLQLKETLATQEPTDN----------------------------QVRLRKRKEIREDRDRARLDSMVLLIMKLDQLDQDIENALSTSSSPSGTPTNLRRHVPDLESGSESGADTISVNQTRVNLSSDTESTDLPSSTPVANSG-----------------------TKPKTTAIQGISEKEKAEIEAKEACDWLRATG---------FPQYAQLYE-DFLFPIDISLVKREHDFLDRDAIEALCRRLNTLNKCAVMKLEISPHRKRSD---------------------------------------------------------------------------------------------------DSDEDEPCAISGKWTFQRDSKRWSRLEEF--------------------------------DVFSPKQDLVP-----GSPDDSHPKD--------GPSPGGTLMDLSERQEVSSVR-----------SLSSTG-SLPSHAPP-SEDAATPRTNSVISVCSSSNLAGNDDSFGS-LPSPKELSSFSFSMKG------HEKTAKSKTR-----SLLKRMESLKLKSSHHS------------------------------------------------------KHKAPSKLGLIISGPILQEGMDE---------------------------EKLKQLNCVEISALNGNRINVPMVRKRSVSNSTQTSSS----------SSQSETSS--AVSTPSPVTRTRSLSACN---KRVGMYLEGFDPFNQSTFNN-------------------------------------------------------------------------VVEQNFKN------RESYPEDTVFYIPEDH------------------------------KPGTFPKALTNGSFSPSGNNGSVNWRTGSFHG------------PGHISLRRENSSD----SPKELKRRNSSSSMSSRLSIYDNVPGS--------------------ILYSSSGDLADLENEDIFPELDDILYHVKGMQRIVNQWSEK---------FSDEGDSDSALDSVSPCPSSPKQIHLDVDNDRTTPSDLDSTGNSLNEPEEP----------------------------------------------------------------------------SEIPERRDSGVGASLTRSNR-HRLRWHSFQSSHRP---------------SLNSVSLQINCQSVAQMNLLQKYSLLKLTALLEKYTPSNKHGFSWAVPKFMKRIKVPDYKDRSVFGVPLTVNVQRTGQPLPQSIQQAMRYLRNHCLDQVGLFRKSGVKSRIQALRQMNEGAIDC----VNYEGQSAYDVADMLKQYFRDLPEPLMTNKLSETFLQIYQYVPKDQRLQAIKAAIMLLPDENREVLQTLLYFLSDVTAAVKENQMTPTNLAVCLAPSLFHLNTLKRENSSPRVMQRK-QSLGKPDQKDLNENLAATQGLAHMIAECKKLFQVPEEMSRCRNSYTEQELKPLTLEALGHLGNDDSADYQHFLQDCVDGLFKEVKEKFKGWVSYSTS--EQAELSYKKVSEGPPLRLWRSVIEVPAVPEEILKRLLKEQHLWDVDLLDSKVIEILDSQTEIYQYVQNSMAPHPARDYVVLRTWRTNLPKGACALLLTSVDHDRAPVVG--VRVNVLLSRYLIEPCGPGKSKLTYMCRVDLRGHMPEWYTKSFGHLCAAEVVKIRDSFSNQNTETKDTKSR", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9R0Z9-1", "uniprot_id": "RHG07_MOUSE", "id": "Q9R0Z9-1", "name": "Rho GTPase-activating protein 7", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MCR-----------------------DEPDTMILT--------QIEAKEACDWLRVTG---------FPQYAQLYE-DLLFPVDIALVKREHDFLDRDAIEALCRRLNTLNKCAVMKLEISPHRKRSE---------------------------------------------------------------------------------------------------DSDEDEPCAISGKWTFQRDSKRWSRLEEF--------------------------------DVFFPKQDPIP-----GSPDNSRLQS--------ATSHESMLTDLSEHQEVASVR-----------SLSSTSSSVPTHAAH-SGDATTPRTNSVISVCSSGHFVGNDDSFSS-LPSPKELSSFSFSMKGH-----HEKNTKSKTR-----SLLKRMESLKLKGSHHS------------------------------------------------------KHKAPSKLGLIISAPILQEGMDE---------------------------AKLKQLNCVEISALNGNHINVPMVRKRSVSNSTQTSSS----------SSQSETSS--AVSTPSPVTRTRSLSTCN---KRVGMYLEGFDPFSQSTLNN-------------------------------------------------------------------------VTEQNYKN------RESYPEDTVFYIPEDH------------------------------KPGTFPKALSHGSFCPSGNS-SVNWRTGSFHG------------PGHLSLRRENSHD----SPKELKRRNSSSSLSSRLSIYDNVPGS--------------------ILYSSSGELADLENEDIFPELDDILYHVKGMQRIVNQWSEK---------FSDEGDSDSALDSVSPCPSSPKQIHLDVDHDRRTPSDLDSTGNSLNEPEEP----------------------------------------------------------------------------TDIPERRDSGVGASLTRCNR-HRLRWHSFQSSHRP---------------SLNSVSLQINCQSVAQMNLLQKYSLLKLTALLEKYTPSNKHGFSWAVPKFMKRIKVPDYKDRSVFGVPLTVNVQRSGQPLPQSIQQAMRYLRNHCLDQVGLFRKSGVKSRIQALRQMNESAEDN----VNYEGQSAYDVADMLKQYFRDLPEPLMTNKLSETFLQIYQYVPKDQRLQAIKAAIMLLPDENREVLQTLLYFLSDVTAAVKENQMTPTNLAVCLAPSLFHLNTLKRENSSPRVMQRK-QSLGKPDQKDLNENLAATQGLAHMIAECKKLFQVPEEMSRCRNSYTEQELKPLTLEALGHLNSDQPADYRHFLQDCVDGLFKEVKEKFKGWVSYPTS--EQADLSYKKVSEGPPLRLWRSTIEVPAAPEEILKRLLKEQHLWDVDLLDSKVIEILDSQTEIYQYVQNSMAPHPARDYVVLRTWRTNLPRGACALLLTSVDHDRAPVAG--VRVNVLLSRYLIEPCGSGKSKLTYMCRADLRGHMPEWYSKSFGHLCAAEVVKIRDSFSNQNTESKDTRSR", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0AC58JHT8-1", "uniprot_id": "A0AC58JHT8_DANRE", "id": "A0AC58JHT8-1", "name": "Rho GTPase-activating protein 7", "aln": "-----------------------------------------------------MPVAIRNRSWEDHVTSPRTGLQYSYDDLDLVCCHARHRRGRCASMPECGHHHLYPQDDIGNGTKKMERILQ------------------------------KFKNETQPNCEDVKSQLLTSRDAVNEKAQLESEQDNRLLSNNVADQDELQHSALGNLQTHNGDADNKKLNKDKVSSAISLSHLVPSAEALDQTNGLGNVLKDGISLNNTVKEDCSELTHPKEETSVENTES-MVKVNVGSEKLVYEHMNVTSSITEITNKPPTSDSSADPCDNEEGHCCETSEQAILKCIKTERSSKPMSSSSTSQEDHHIPHTEDANKANLACKDCNMTPEENGDGIFKCADGDTLN-----------------------------------VGCINPHACESSQLKECGVIDIMDTWHDCSSKLQTIHEGSCPESGDDSSAQISGDGPEEPTCRGLNTRN-------------------------------------------------------------CENLTASEDLREPQPEGIYEDHQATQNTAAKDCEMVPKADGSIVKLRTRKSSHEEREKERSRLDSMVLLIMKLDQLDKEIENALS--SSLNSTPNLKRRIISDVDLETLDSAGSLSASSQSLNTPLYRSSSSLSSSGPTGTPG-----------------------ARPKNETSAVLSENDRAEIEAKEACTWLRAAG---------FPQYAQLYE-DGQFPIEISSVTRDHDFLDQDAIEALCRRLNTLNKCALMRLEITPQRKRSE---------------------------------------------------------------------------------------------------DSDEDEPCAISGRWTFQRDSKRWSRMDQLD------------------------------LDVFSPTAGDTGSFAAFLSQDEHFVRGPLQK-EGVNASVESILTDLSEQPEVGSLHSTGS--GGRGGSLSTTVPSSPATTISNANTATTTRASSVASVCSSGTSGANEDSMSDGLPSPLERGTFAFDVKPNLISSAAEKSTRSRAK-----SFLKRMESLRLRTSSNAGSKRK-------------------------------------------------KKGVPGHGRLEISGPVLKEGLDE---------------------------DKLRRLNCVDIATLDRN-----ANRNRSISYSTQTSSGS-------AGSSQSEASSGSAVSTPSPVSRARSHSTAAGSSKRGGMYLEGFDPFNFVVLQP-------------------------------------------------------------------------SEDQDVKENHQTQNKRKEPSSTDENNRRNR------------------------------QSSDNRQMEDEESRVEEGGVIFFYLPEGHKPG------------TFPKALADGGSYHGVDNTSRRPPRRGSSASLDSRMSIYDNVPFS--------------------EVGDDEDEVGEEE-----PKLEDVLERVRGLQQLVNEWPETGIGEEEEDEEEEEGDSDSALDSASPCPSSPLQNRLEETENG---SDQDSTGNPLAERDET----------------------------------------------------------------------------LSSRERCDSGVEASLTRANRTQKLRWPSFQSSHRP---------------SLSSTVLQVGCQSVLQMNLLQKYSLLKLTALLERYTPTNKHGFSWAVPKFMKRIKVRDYKDRSVFGVPLQVIVQRSGQPLPQSIQQAMRYLRSQCLDQVGLFRKSGVKSRIQALRQMNESCGAVGG-GVNYEGQLAYDVADMLKQYFRDLPEPLLTSKLSDTFLQIYQYVPKEQRLQAVRAAVLLLPDENREALQTLLCFLSDVTASVGENQMTCTNLAVCLAPSLFHLNTLRRESSSPRVMNRK-NTLGKPDQRDLNENLAATHGLAHMIQECRKLFQIPEEMSRCRNSYMEQGLSPMRMEVLAENCG--SCNYQSLLKDSIDSLLKEAKDKFKGYDSCSTP--ENAELAYKKVQDGSSLRQWKVCVDVPASAEDVLQRILREQERWDEDLLESRIVETLDHNTEVYQYVRNSMPPHPPRDHVVLRSWMTDLPKGVCTLVSVSVDHESAAVLG--VRANVLTSRYYIEPCGANKSRLAHISRIDCRGRCPEWYNKLYGHLCAAEVVRIRDTFTCLDK--------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A8JR05-1", "uniprot_id": "A8JR05_DROME", "id": "A8JR05-1", "name": "", "aln": "MSNARELALIEKWADIATPATPNRPTLSPTSPPALHRSIVKFCCCPQRRRYNLKQAKSHGGSNKLNVNTLHARNIFVDSDFSYIDDVPRRRQDCHSDYDDCNYDSDCGGDKADDEANDIAAAPRDDGNVALILMNQRNLSEQWRQDNKGNSNSNKAATKTCAVTKSPQSGNEQQQHQQQQQQQQQQRQPTQRLSNSLQQQQQQEQQLQQQQQQQHSNKENTLSYDNNNKPHCNYCKLPDTAEPQTNSNSNSKIDSPKSSQNKMTITTATDTETATATTATATGECGLPAATSQEFVGAATEVLCNDKATLTAATPAATATTAATTPKPRIAARPTTPSRLKTVIKTTMVKRSPSHDSTATAAHVLLPHSCSSNSNSSSNNIGAHDEPRRSVRERIAAFAAGNEQQQAARQHDKVKKLTKMQCNSNTNQNNMTAEDVKSAISNSSSSSSNQLQQQQHQTLINGQAATVPAATAAATGGVAAATSGRTSAIAADTTRYKSGLSDVAANGDVDGRPTSSATTSVVATGAPSVFSTGCATMPRTRQYGSNVAAALATGATLATSATSATSSATGATSPGSHTMTADKKFLSQAAPVQGHHHHKLQFADKADSELAALDNLDLAHSLDLLDVDGEDPYGALQDYLERVKREINEVFELRKVQRLEQQLREQLEERLSQAGVQQLDELSRSTESDSGFDSSSTTATSGTPATATAAGAGAVTSGKPVTTKLRALPPPPLSPTKTTTNSMPTPPVQADDVNIWACKFLRDLDSLMAAGDKLPPHLAALAEGSGSGSASSSPTSRTAPILLSAAASAAIQSRLGKGSSSIMEHQLQQQQQQQNGLVLKPEKHATIPLQSFYLDCGRNEASPATKSNVAYMRTLSAPNGGFASGGGGGAARGSGAPALPPQSQRKSLACPPLNGQADTITPTPATHKLTNFQSALKIEEMAAAKGTAMATGESQLATTIEDLKSRRQRQLSGGDMETMLASQPMSMPKRVGINHAVLTSRNAITPPPASASSASQSAASVHSAKGSSSAGTTPGYLVDVTKKGSTSTIWTSEESILRSVGAVDEDNNSTSSSSACEEATGVLSSGKSGISLDSSGLDNDNNESGIGTATPPKDMSHYWKSHHLQHHHHHHHRKCTGSAQDNESVSSLEALRKMKFQKSGSVASSDDPDVLEVLSQCGSGGEANESQDDMLDEEKDKMSKSQDYDEIWDCDCTDGDASSASGGGGVTATPVILRRKYTAPPPILVPRTQRSHSLDHYHSPQPLVHPRKVLPIHHHALKSKERGQLSLVLRQEPFQSLLSPSATAANQLHHFVELPSPSSASLHSGLGDSGGIQELCTKSNSAPMLLKEREMSRRFDNFEAQHLTLRYSRSQSDRYLAEIEAVEACKWLRAAGFPQYAQMYEDHQFPIDLNNVAKDHTNLENDQLQSLYRRLCVLNRCATMRLDQSHKPQTPQQKEESDDENFALSEHWTFQPHIRRWSRIGEMGLELPPPGLLSLNVEKTESSSKESSPDRFEEDGAGITLVTPGCSKAGGIPNDGSSLGEGSDSGRLRRSGSERIKDQAKALLRRVESIKSRRRKRQNRENVVISGPTVLDLSQFGQRSSLRKPDAVYSTPPSPSALSPMHTFPKAPFFGNDLKVPSHSDNFLSPNR-SSPKRTPTTPRSMRTSPLHFFSSPMSQLKEGKSDDSSSYYSDSQESSTGGKLSLRKPSKARRFLQRTGKVDDIGAHSDSECHQGRKLLIKDANSNTTEVKVKKLTRGGSLNLGKDPKKRDGFRSSSFRSRSTSRKEAKNDEDTAGATTNGGSKRQPVVRWHSFQMEERPNMIFRKCFSKKIEPLQEDAGGMPFAAMSAGQLQIIRKLALVTLTGHMERYCPSHRSGWNWELPKFIKKIKMPDYKDKKVFGVPLLMILQRSGQTLPLAVRAAFRWLQLNALDQVGIFRKSGGKSRIMKLREQIEVTDSTAECMDVFDLQQAYDVADMLKQYFRELPESLLTTKMSETFVAIFQHLPAEVRLDAVQCAVLLLPDENREILYVLLEFLTIVAANSQQNQMTSNNLGVCLAQSIFHSSISTGSASVSASPRRKGKGSGMPDMKELAEAKASHECLSFMIEHYKQIYTAAKEKLSKCNFSYMEESKPLPLEALG--EGMQFHNWRGYLYECTSATIKEGREKTRGWFSINSLNDSSVDIAYKKVGDGHPLRLWRCSTEIEGPPKEVLEFVIKQRASWDTNLLQCQTVKKLDDRTEIYQYALDGQLTT---DFCVLRSWQTDLPRGACVIVETSIDHAKAKPLFGAVRGVVLASRYLIEPCGSGRSRVMHLARVDVKGKTPEWYNKNYGHICSHYLSRIRLAFKHVADGPESKV--", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ... : ** :** . *: * * * . . . : ..* :* * .* : ...::*. :: ::::.: . :* .* .* :*: : :::: *: . * .: : . * *:::: ...:: ::. * .: .. . .* *: **. *::* . ..* : . : . : .:. . :: * *: :..:::: * ... : : :*:. *: :: : : : . :: * : :::. .* *.:* .:. .. : . : * . : . ** *. : : .. :.. ... .. :. : .* . * . * .* : * * * : . :** * : . . . . *: . :: .: * . . .. *.*. *. *. : : : . *: .***. * . . . : *:. :: .:* :** *** ..** . .: : . . *. *:::::* :*:.**. :*:* *::: *:.* :***:*:**: ****:.****** : :**:**.** ::: *:*:*: :.*****:***** **** **: * :: * *************:***.*:*.*:*:**: *:*::* : **:*::.*::******** * .** **: *:* :**** .**.**** *:** . . * . .** : * ** ::* * *: . *:.** . :::: .:* * : .*: :*.*. . ::: * :. .. :** ::* :*: * : ...:::**** :* .** *: :: . .:::*: ::::: ** :**:.: :: ** .**:***. :. . *. ***:* *:**:*.*.:: .*:** * ** ** *** *****..:*:: ::.* * :*: ****.* :**:*: : :** :*. ", "identical_positions": 267, "similar_positions": 359, "identity": "11.32%" }, { "cls_id": "homologset.agr.MGI:1354950", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9QYK3-1", "uniprot_id": "NRBF2_RAT", "id": "Q9QYK3-1", "name": "Nuclear receptor-binding factor 2", "aln": "------------------------MEVMEGPLNLAHQQSRRADRLLAAGKYEEAISCHKKATAYLSEAMK---LTQSEQAHLSLELQRDSHMKQLLLIQERWKRAKREERLKAQQSTDRDGVPHLQASHRPS-EDSEGQSPLLSQTYIPSTEKRLPEEQGVFDRDPDTLLFLLQQKNEPSEPCIGSKAPKDDKTIIEEQATKIAELKRHVEFLVAENERLRKENKQLKAEKARLLKGPAEKELDVDADFVEKSELWGLPPHSDTATASSTWQKFAANTGKAKDIPIPNLPPLDFPSPELPLMELSEDILKGFMND-------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0A8I6GHP4-1", "uniprot_id": "A0A8I6GHP4_RAT", "id": "A0A8I6GHP4-1", "name": "Nuclear receptor-binding factor 2", "aln": "------------------------MEVMEGPLNLAHQQSRRADRLLAAGKYEEAISCHKKATAYLSEAMK---LTQSEQAHLSLELQRDSHMKQLLLIQERWKRAKREERLKAQQRTDRDGVPHLQASHRPS-EDSEGQSPLLSQTYIPSTEKHLPEVQGVFDRDPDTLLFLLQQKNEPSEPCIGSKAPKDDKTIIEEQATKIAELKRHVEFLVAENERLRKENKQLKAEKARLLKGPAEKELDVDADFVEKSELWGLPPHSDTATASSTWQKFAANTGKAKDIPIPNLPPLDFPSPELPLMELSEDILKGFMND-------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8VCQ3-1", "uniprot_id": "NRBF2_MOUSE", "id": "Q8VCQ3-1", "name": "Nuclear receptor-binding factor 2", "aln": "------------------------MEVMEGPLNLAHQQSRRADRLLAAGKYEEAISCHRKATTYLSEAMK---LTESEQAHLSLELQRDSHMKQLLLIQERWKRAKREERLKAQQSTERDGAPHLQAPPRPS-EDAEGQSPLLSQPYIPSTERRLPEVQGVFDRDPDTLLFLLQQKNEPSEPCIGSKAPKDDKTIIEEQATKIADLKRHVEFLVAENERLRKENKQLKAEKARLLKGTAEKELDVDADFVEKSELWGLPSHSESAAASSTWQKFAANTGKAKDIPIPNLPPLDFPSPELPLMELSEDILKGFMND-------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q96F24-1", "uniprot_id": "NRBF2_HUMAN", "id": "Q96F24-1", "name": "Nuclear receptor-binding factor 2", "aln": "------------------------MEVMEGPLNLAHQQSRRADRLLAAGKYEEAISCHKKAAAYLSEAMK---LTQSEQAHLSLELQRDSHMKQLLLIQERWKRAQREERLKAQQNTDKDAAAHLQTSHKPSAEDAEGQSP-LSQKYSPSTEKCLPEIQGIFDRDPDTLLYLLQQKSEPAEPCIGSKAPKDDKTIIEEQATKIADLKRHVEFLVAENERLRKENKQLKAEKARLLKGPIEKELDVDADFVETSELWSLPPHAETATASSTWQKFAANTGKAKDIPIPNLPPLDFPSPELPLMELSEDILKGFMNN-------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AB13AB16-1", "uniprot_id": "A0AB13AB16_DANRE", "id": "A0AB13AB16-1", "name": "", "aln": "MVNLLSVNKEVATVKTAKPHAQIEMEVIDSPLNRAHHYGRRADQLVMKGKYEEAIECHQEAAELLKEASS---MTQSQQVRLSLELQRDRHLQQQRLIQMSCRQTQLKG-------------------------------------------------------------ELLVSSARPSSSVLGCKTAKDDKTRLEEQSTAIADLWRLVLVLLMDNKRLLEENKRLNAENVGLTMR------------------------------RDPYEEMQSPSASQTQPVFLSLRLLEESPDLQQLMDTAEHS--------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "E1JHX0-1", "uniprot_id": "E1JHX0_DROME", "id": "E1JHX0-1", "name": "Nuclear receptor-binding factor 2 MIT domain-containing protein", "aln": "--------------------------MDCAPLNLAHFHERRSERFIRNHRYEEAIKALETSLIYMQDAQKRVALPKSKEVLDTLTLDFQRKLRQIEMRKTQHGLNKLKDYAPLKETS------------------------------------------------PMLPLRPEAGASGGAGGSAQSVAKAIDKTVQDFDAKFTSSLVAKASSTLAHSEPHMETLKKSDSAQE-----------------------------------EQEHDTCDQRLAGSGDLDLPSLAPLELPSFDYSLFTSSSAPSLASYAGMAESFQK", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : .*** ** **::::: :*****.. . : :.:* . :.:*::. :* *: : :::* : : : : : . : *** : ::. :.* . : ..: : *: .: : . : . : : .* *: .. *: :. ", "identical_positions": 25, "similar_positions": 63, "identity": "7.76%" }, { "cls_id": "homologset.agr.MGI:1354951", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O35826-1", "uniprot_id": "GLCNE_RAT", "id": "O35826-1", "name": "Bifunctional UDP-N-acetylglucosamine 2-epimerase/N-acetylmannosamine kinase", "aln": "-------------------------------MEKNGNNRK--LRVCVATCNRADYSKLAPIMFGIKTEPAFFELDVVVLGSHLIDDYGNTYRMIEQDDFDINTRLHTIVRGEDEAAMVESVGLALVKLPDVLNRLKPDIMIVHGDRFDALALATSAALMNIRILHIEGGEVSGTIDDSIRHAITKLAHYHVCCTRSAEQHLISMCEDHDRILLAGCPSYDKLLSAKNKD-YMSIIRMWLGDDVKCKDYIVALQHPVTTDIKHSIKMFELTLDALISFNKRTLVLFPNIDAGSKEMVRVMRKKGIEHHPNFRAVKHVPFDQFIQLVAHAGCMIGNSSCGVREVGAFGTPVINLGTRQIGRETGENVLHVRDADTQDKILQALHLQFGKQYPCSKIYGDGNAVPRILKFLKSIDLQEPLQKKFCFPPVKENISQDIDHILETLSALAVDLGGTNLRVAIVSMKGEIVKKYTQFNPKTYEERISLILQMCVEAAAEAVKLNCRILGVGISTGGRVNPQEGVVLHSTKLIQEWNSVDLRTPLSDTLHLPVWVDNDGNCAAMAERKFGQGKGQENFVTLITGTGIGGGIIHQHELIHGSSFCAAELGHLVVSLDGPDCSCGSHGCIEAYASGMALQREAKKLHDEDLLLVEGMSVPKDEAVGALHLIQAAKLGNVKAQSILRTAGTALGLGVVNILHTMNPSLVILSGVLASHYIHIVRDVIRQQALSSVQDVDVVVSDLVDPALLGAASMVLDYTTRRIH", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q91WG8-1", "uniprot_id": "GLCNE_MOUSE", "id": "Q91WG8-1", "name": "Bifunctional UDP-N-acetylglucosamine 2-epimerase/N-acetylmannosamine kinase", "aln": "-------------------------------MEKNGNNRK--LRVCVATCNRADYSKLAPIMFGIKTEPAFFELDVVVLGSHLIDDYGNTYRMIEQDDFDINTRLHTIVRGEDEAAMVESVGLALVKLPDVLNRLKPDIMIVHGDRFDALALATSAALMNIRILHIEGGEVSGTIDDSIRHAITKLAHYHVCCTRSAEQHLISMCEDHDRILLAGCPSYDKLLSAKNKD-YMSIIRMWLGDDVKCKDYIVALQHPVTTDIKHSIKMFELTLDALISFNKRTLVLFPNIDAGSKEMVRVMRKKGIEHHPNFRAVKHVPFDQFIQLVAHAGCMIGNSSCGVREVGAFGTPVINLGTRQIGRETGENVLHVRDADTQDKILQALHLQFGKQYPCSKIYGDGNAVPRILKFLKSIDLQEPLQKKFCFPPVKENISQDIDHILETLSALAVDLGGTNLRVAIVSMKGEIVKKYTQFNPKTYEERISLILQMCVEAAAEAVKLNCRILGVGISTGGRVNPQEGVVLHSTKLIQEWNSVDLRTPLSDTLHLPVWVDNDGNCAAMAERKFGQGKGQENFVTLITGTGIGGGIIHQHELIHGSSFCAAELGHLVVSLDGPDCSCGSHGCIEAYASGMALQREAKKLHDEDLLLVEGMSVPKDEAVGALHLIQAAKLGNVKAQSILRTAGTALGLGVVNILHTMNPSLVILSGVLASHYIHIVKDVIRQQALSSVQDVDVVVSDLVDPALLGAASMVLDYTTRRIH", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9Y223-1", "uniprot_id": "GLCNE_HUMAN", "id": "Q9Y223-1", "name": "Bifunctional UDP-N-acetylglucosamine 2-epimerase/N-acetylmannosamine kinase", "aln": "-------------------------------MEKNGNNRK--LRVCVATCNRADYSKLAPIMFGIKTEPEFFELDVVVLGSHLIDDYGNTYRMIEQDDFDINTRLHTIVRGEDEAAMVESVGLALVKLPDVLNRLKPDIMIVHGDRFDALALATSAALMNIRILHIEGGEVSGTIDDSIRHAITKLAHYHVCCTRSAEQHLISMCEDHDRILLAGCPSYDKLLSAKNKD-YMSIIRMWLGDDVKSKDYIVALQHPVTTDIKHSIKMFELTLDALISFNKRTLVLFPNIDAGSKEMVRVMRKKGIEHHPNFRAVKHVPFDQFIQLVAHAGCMIGNSSCGVREVGAFGTPVINLGTRQIGRETGENVLHVRDADTQDKILQALHLQFGKQYPCSKIYGDGNAVPRILKFLKSIDLQEPLQKKFCFPPVKENISQDIDHILETLSALAVDLGGTNLRVAIVSMKGEIVKKYTQFNPKTYEERINLILQMCVEAAAEAVKLNCRILGVGISTGGRVNPREGIVLHSTKLIQEWNSVDLRTPLSDTLHLPVWVDNDGNCAALAERKFGQGKGLENFVTLITGTGIGGGIIHQHELIHGSSFCAAELGHLVVSLDGPDCSCGSHGCIEAYASGMALQREAKKLHDEDLLLVEGMSVPKDEAVGALHLIQAAKLGNAKAQSILRTAGTALGLGVVNILHTMNPSLVILSGVLASHYIHIVKDVIRQQALSSVQDVDVVVSDLVDPALLGAASMVLDYTTRRIY", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AB32T4X8-1", "uniprot_id": "A0AB32T4X8_DANRE", "id": "A0AB32T4X8-1", "name": "Bifunctional UDP-N-acetylglucosamine 2-epimerase/N-acetylmannosamine kinase", "aln": "MMPGHARNPHSVQVRNSHELYYLRMQRAQEKMERLEKPKKERLRVCVATCNRADYSKLAPIMFGIKSHPDIFDLEVVVLGSHLIDDYGNTFRMIEQDDFDIGSKLHTIVRGEDEAAMVESVGLALVKLPDVLQRLAPDILLVHGDRFDALALATAAALMNIRILHLEGGEVSGTIDDSIRHAISKLAHYHAVCTLSAERHLISMCEDHSRILLAGCPSYDKLLSAYKRDDYADIIKSWIGDDVKEQDYIVALQHPVTTDIKNSIKIYELMLDALISFNKKTLILFPNIDAGSKEMVRVMRRKGIEQHQNFRAVKHVPFDQFIQLVAHAGCMIGNSSCGVREAGAFGTPVINLGTRQTGRETGENVLHVRDADTHNKIYHALELQFGKRYPCSKIYGDGNAVQRILKFLQTIDLSEPLQKKFCFPPVKECISQDIDHILETQSALSVDLGGTNLRVGIVSMKGKVVKKYVQLNPKTFEERIELILTMCKQAMADAVHLNCRILGVGVSTGGRVNPQDGVVLHSTKLIKEWSSVDIRTPLSSALHLPVWVDNDGNCAALAERKFGHGKGVENFVTIITGTGIGGGIIQHNELIHGNTFCAAELGHIVVSLEGPECMCGGHGCIEAYSSGLALQREAKRLHDEDLLLVEGMTLNNKEQVNAIHLINAARLGNSKAETVLHTAGTALGLGIVNILHMINPSLVILSGVLAVHYETPVRQVIGQRALLTAQGTKVMVSDLEDPALLGAASMVLDYTTRRTY", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " **: : :* ************************:.* :*:*:***************:**********.::****************************:** ***::*************:**********:*****************:******. ** ***:*********.**************** ::* * .**: *:***** :***************:***::** *********:**:*****************:****:* *********************************.************** ****************::** :**.*****:************* ******::***.************** *********** ***:**********.******::****.*:****:****.*** ** :* *:**:*********:********::*:********:**.***:*****.:***************:******:*** *****:***********:::*****.:********:****:**:* **.*******:**:*******:************:: :.* *.*:***:**:*** **:::*:*********:***** :************ ** *::** *:** :.*...*:**** ****************** :", "identical_positions": 585, "similar_positions": 102, "identity": "77.38%" }, { "cls_id": "homologset.agr.MGI:1354952", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "B1H219-1", "uniprot_id": "B1H219_RAT", "id": "B1H219-1", "name": "Dickkopf-related protein 3", "aln": "MQWLRDILLCMLLAAVVPTAPTPAPTATWTPAEPGPALNYPQEEATLNEMFREVEELMEDTQHKLRSAVEEMEAEEAAARTSSEVTLSSLPANYHNETNTETRMENNTAHVHREVHKITNNQSGQTVFSETVITSVEDGEGKKSHECIIDEDCGPTRYCQFSSFKYTCQPCRDQQMLCTRDSECCGDQLCAWGHCTQKATKGSNGTICDNQRDCQPGLCCAFQRGLLFPVCTPLPVEGELCHDPTSQMLDLITWELEPEGALDRCPCASGLLCQPHSHSLVYMCKPAFVGSHDHNEESQLPREALDDYEDVGFIGEVRQELEDLERSLAQEMAFEEATPVDS--LGGEKI-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9QUN9-1", "uniprot_id": "DKK3_MOUSE", "id": "Q9QUN9-1", "name": "Dickkopf-related protein 3", "aln": "MQRLGGILLCTLLAAAVPTAPAPSPTVTWTPAEPGPALNYPQEEATLNEMFREVEELMEDTQHKLRSAVEEMEAEEAAAKTSSEVNLASLPPNYHNETSTETRVGNNTVHVHQEVHKITNNQSGQVVFSETVITSVGDEEGKRSHECIIDEDCGPTRYCQFSSFKYTCQPCRDQQMLCTRDSECCGDQLCAWGHCTQKATKGGNGTICDNQRDCQPGLCCAFQRGLLFPVCTPLPVEGELCHDPTSQLLDLITWELEPEGALDRCPCASGLLCQPHSHSLVYMCKPAFVGSHDHSEESQLPREAPDEYEDVGFIGEVRQELEDLERSLAQEMAFEGPAPVES--LGGEEEI", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9UBP4-1", "uniprot_id": "DKK3_HUMAN", "id": "Q9UBP4-1", "name": "Dickkopf-related protein 3", "aln": "MQRLGATLLCLLLAAAVPTAPAPAPTATSAPVKPGPALSYPQEEATLNEMFREVEELMEDTQHKLRSAVEEMEAEEAAAKASSEVNLANLPPSYHNETNTDTKVGNNTIHVHREIHKITNNQTGQMVFSETVITSVGDEEGRRSHECIIDEDCGPSMYCQFASFQYTCQPCRGQRMLCTRDSECCGDQLCVWGHCTKMATRGSNGTICDNQRDCQPGLCCAFQRGLLFPVCTPLPVEGELCHDPASRLLDLITWELEPDGALDRCPCASGLLCQPHSHSLVYVCKPTFVGSRDQDGEILLPREVPDEYEVGSFMEEVRQELEDLERSLTEEMALREPAAAAAALLGGEEI-", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "** * *** ****.*****:*:**.* :*.:*****.****************************************::****.*:.**..*****.*:*:: *** ***:*:*******:** ********** * **::************: ****:**:*******.*:***************.*****: **:*.*****************************************:*::**********:***********************:***:****:*:. * ****. *:** .*: *************::***:. .:.. : ****: ", "identical_positions": 269, "similar_positions": 56, "identity": "76.64%" }, { "cls_id": "homologset.agr.MGI:1354953", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O88382-1", "uniprot_id": "MAGI2_RAT", "id": "O88382-1", "name": "Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2", "aln": "----------MSKSLKKKSHWTSKVHESVIGRNPEGQLGFELKGGAENGQ-FPYLGEVKPGKVAYESGSKLVSEELLLEVNETPVAGLTIRDVLAVIKHCKDPLRLKCVKQGGIVDKDLRHYLNLRFQKGSVDHELQQIIRDNLYLRTVPCTTRPHKEG--EVPGVDYIFITVEDFMELEKSGALLESGTYEDNYYGTPKPPAEPAPLLLNVTDQ----ILPGATPSAEGKRKRNKSVTNMEKASIEPPEEEEEERPVVNGNGVVITPESSEHEDKSAGASGETPSQPYP--APVYSQPEELKDQMDDTKSTK-PEENEDSDPLPDNWEMAYTEKGEVYFIDHNTKTTSWLDPRLAKKAK-PAEECKENELPYGWEKIDDPIYGTYYVDHINRRTQFENPVLEAKRKLQQHN-MPHTELG------------------TKPLQAPGFREKP----------LFTRDASQLKGTFLSTTLKKSNMGFGFTIIGGD-----EPDEFLQVKSVIPDGPAAQDGKMETGDVIVYINEVCVLGHTHADVVKLFQSVPIGQSVNLVLCRGYPLPFDPEDP-ANSMVPPLAIMERPPPVMVNGRHNYETYLEYISRTSQSVPDITDRPPHSLHSMPADGQLDGTYPP------PVHDDNVSVASS-----GATQA-ELMTLTIVKGAKGFGFTIADSPTGQRVKQILDIQGCPGLCEGDLIVEINQQNVQNLSHTEVVDILKDCPVGSETSLIIHRG---GFFSPWKTPKPMVDRWENQGSPQTSLSAPAVPQSLPFPP-ALHRSSFPDSTEAFDPRKPDPYELYEKSRAIYESRQQVPPRTSFRMDSSGPDYKELDVHLRRMESGFGFRILGGD--------EPGQPILIGAVIAMGSADRDGRLHPGDELVYVDGIPVAGKTHRYVIDLMHHAARNGQVNLTVRRKVLCG-GEPCPENGRSPGSVSTHHSSPRSDYATYANSNHAAPSNN-------ASPPEGFASHSLQTSDVIIHRKENEGFGFVIISSLNRPESGATITVPHKIGRIIDGSPADRCAKLKVGDRILAVNGQSIINMPHADIVKLIKDAGLSVTLRIIPQEELNNPTSAPSSEKQSPMAQQH----------------------SPLAQQHSPLAQPSPATPNSPVAQPAP-------------------------------------------------------------PQPLQLQGHENSYRSEVKARQDVKPDIRQPPFTDYRQPPLDYRQPPGGDYSQPSPLDYR--------QHSPDTRQYPLSDYRQPQDFDYFTVDMEKGAKGFGFSIRGGREYKMDLYVLRLAEDGPAIRNGRMRVGDQIIEINGESTRDMTHARAIELIKSGGRRVRLLLKRGTGQVPEY--------------------------GMVPSS---------------------------------LSMCMKSDKHGSPYFYLLGHPKDTTNP----------------------TPGALPLP-----------PPQACRK-------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9WVQ1-1", "uniprot_id": "MAGI2_MOUSE", "id": "Q9WVQ1-1", "name": "Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2", "aln": "----------MSKSLKKKSHWTSKVHESVIGRNPEGQLGFELKGGAENGQ-FPYLGEVKPGKVAYESGSKLVSEELLLEVNETPVAGLTIRDVLAVIKHCKDPLRLKCVKQGGIVDKDLRHYLNLRFQKGSVDHELQQIIRDNLYLRTVPCTTRPHKEG--EVPGVDYIFITVEEFMELEKSGALLESGTYEDNYYGTPKPPAEPAP-LLNVTDQ----ILPGATPSAEGKRKRNKSVTNMEKASIEPPEEEEEERPVVNGNGVVITPESSEHEDKSAGASGETPSQPYP--APVYSQPEELKDQMDDTKPTK-PEENEDSDPLPDNWEMAYTEKGEVYFIDHNTKTTSWLDPRLAKKAK-PPEECKENELPYGWEKIDDPIYGTYYVDHINRRTQFENPVLEAKRKLQQHN-MPHTELG------------------AKPLQAPGFREKP----------LFTRDASQLKGTFLSTTLKKSNMGFGFTIIGGD-----EPDEFLQVKSVIPDGPAAQDGKMETGDVIVYINEVCVLGHTHADVVKLFQSVPIGQSVNLVLCRGYPLPFDPEDP-ANSMVPPLAIMERPPPVMVNGRHNYETYLEYISRTSQSVPDITDRPPHSLHSMPADGQLDGTYPP------PVHDDNVSMASS-----GATQA-ELMTLTIVKGAQGFGFTIADSPTGQRVKQILDIQGCPGLCEGDLIVEINQQNVQNLSHTEVVDILKDCPVGSETSLIIHRG---GFFSPWKTPKPMMDRWENQGSPQTSLSAPAVPQNLPFPP-ALHRSSFPDSTEAFDPRKPDPYELYEKSRAIYESRQQVPPRTSFRMDSSGPDYKELDVHLRRMESGFGFRILGGD--------EPGQPILIGAVIAMGSADRDGRLHPGDELVYVDGIPVAGKTHRYVIDLMHHAARNGQVNLTVRRKVLCG-GEPCPENGRSPGSVSTHHSSPRSDYATYSNSNHAAPSSN-------ASPPEGFASHSLQTSDVVIHRKENEGFGFVIISSLNRPESGATITVPHKIGRIIDGSPADRCAKLKVGDRILAVNGQSIINMPHADIVKLIKDAGLSVTLRIIPQEELNSPTSAPSSEKQSPMAQQH----------------------SPLAQQ-SPLAQPSPATPNSPVAQPAP-------------------------------------------------------------PQPLQLQGHENSYRSEVKARQDVKPDIRQPPFTDYRQPPLDYRQPPGGDYSQPPPLDYR--------QHSPDTRQYPLSDYRQPQDFDYFTVDMEKGAKGFGFSIRGGREYKMDLYVLRLAEDGPAIRNGRMRVGDQIIEINGESTRDMTHARAIELIKSGGRRVRLLLKRGTGQVPEY--------------------------GMVPSS---------------------------------LSMCMKSDKHGSPYFYLLGHPKDTTNP----------------------TPGVLPLP-----------PPQACRK-------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q86UL8-1", "uniprot_id": "MAGI2_HUMAN", "id": "Q86UL8-1", "name": "Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2", "aln": "----------MSKSLKKKSHWTSKVHESVIGRNPEGQLGFELKGGAENGQ-FPYLGEVKPGKVAYESGSKLVSEELLLEVNETPVAGLTIRDVLAVIKHCKDPLRLKCVKQGGIVDKDLRHYLNLRFQKGSVDHELQQIIRDNLYLRTVPCTTRPHKEG--EVPGVDYIFITVEDFMELEKSGALLESGTYEDNYYGTPKPPAEPAPLLLNVTDQ----ILPGATPSAEGKRKRNKSVSNMEKASIEPPEEEEEERPVVNGNGVVVTPESSEHEDKSAGASGEMPSQPYP--APVYSQPEELKEQMDDTKPTK-PEDNEEPDPLPDNWEMAYTEKGEVYFIDHNTKTTSWLDPRLAKKAK-PPEECKENELPYGWEKIDDPIYGTYYVDHINRRTQFENPVLEAKRKLQQHN-MPHTELG------------------TKPLQAPGFREKP----------LFTRDASQLKGTFLSTTLKKSNMGFGFTIIGGD-----EPDEFLQVKSVIPDGPAAQDGKMETGDVIVYINEVCVLGHTHADVVKLFQSVPIGQSVNLVLCRGYPLPFDPEDP-ANSMVPPLAIMERPPPVMVNGRHNYETYLEYISRTSQSVPDITDRPPHSLHSMPTDGQLDGTYPP------PVHDDNVSMASS-----GATQA-ELMTLTIVKGAQGFGFTIADSPTGQRVKQILDIQGCPGLCEGDLIVEINQQNVQNLSHTEVVDILKDCPIGSETSLIIHRG---GFFSPWKTPKPIMDRWENQGSPQTSLSAPAIPQNLPFPP-ALHRSSFPDSTEAFDPRKPDPYELYEKSRAIYESRQQVPPRTSFRMDSSGPDYKELDVHLRRMESGFGFRILGGD--------EPGQPILIGAVIAMGSADRDGRLHPGDELVYVDGIPVAGKTHRYVIDLMHHAARNGQVNLTVRRKVLCG-GEPCPENGRSPGSVSTHHSSPRSDYATYTNSNHAAPSSN-------ASPPEGFASHSLQTSDVVIHRKENEGFGFVIISSLNRPESGSTITVPHKIGRIIDGSPADRCAKLKVGDRILAVNGQSIINMPHADIVKLIKDAGLSVTLRIIPQEELNSPTSAPSSEKQSPMAQQ-----------------------SPLAQQ-SPLAQPSPATPNSPIAQPAP-------------------------------------------------------------PQPLQLQGHENSYRSEVKARQDVKPDIRQPPFTDYRQPPLDYRQPPGGDYQQPPPLDYRQPPLLDYRQHSPDTRQYPLSDYRQPQDFDYFTVDMEKGAKGFGFSIRGGREYKMDLYVLRLAEDGPAIRNGRMRVGDQIIEINGESTRDMTHARAIELIKSGGRRVRLLLKRGTGQVPEYDEPAPWSSPAAAAPGLPEVGVSL-DDGLAPFSPSHPAPPSDPSHQISPGPTWDIKREHDVRKPKELSACGQKKQRLGEQRERSASPQRAARPRLEEAPGGQGRPEAGRPASEARAPGLAAAD-----------AADAARAGGKEAPRAAAGSELCRREGPGAAPAFAGPGGGGSGALEAEGRAGARAGPRPGPRPPGGA-----------------PARKAAVAPGPWKVPGSDKLPSVLKPGASAASR", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AC58IYC1-1", "uniprot_id": "A0AC58IYC1_DANRE", "id": "A0AC58IYC1-1", "name": "Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1", "aln": "----------MSKSLKKKNHWTNKVHEALLGRNKEGELGFDLKGGAENGN-FPYFGEVKQGKVAIQSG-KLSQDELLLEVNDTPVAGLTIRDVLAVIKHCKDPFRLKCVKQGGVVDKDLRHYLNLRFQKGSVDHELQQIIRDNLYLRTVPCTTRQPKEG--EVPGVDYNFVSVERFMELEKSGALLESGTYEDNFYGTPKPPAEPTPMLFNVTDQ----LLPGARPSAEWKRKRNKSVSNMEKDSIEPPEEEEEESPIINGNGIAITPESSEHEDKSTDASGDVPVQPCPPETPTLTATDVPEEEGDAPKSPQDLQENDDMGSLPDNWEMAYTEKGEVYFIDHNTKTTSWLDPRLAKKAK-PPEECEEDELPYGWEKIDDPIYGSYYVDHINRRTQFENPVLEAKRRIQQQQQMQSQGLS------------------ALPLPT-IYREKP----------PFTRDATQLKGTFLTTVLQKSNMGFGFTIIGGD-----EPDEFLQVKSVIPEGPAAQDSKMDTGDVIVYINDICVLGTTHADVVKLFQSVPIGQSVTLVLCRGYPLPYDPEDPSASSSMPPLGLVDHP--LLLNGRNNYENYMEYMSLTGRLVPEHGEG--LTPLPHPGDTHLDGSQPPSLTTPGPPPDDSVSMASSSGATAGATVAPELLSLTITKGAEGFGFTIADSPTGQRVKQVLEPQGCPGLCEGDLIVEINQKCLQGLNHTQVVQLLKDCPVGTEATLVIQRGTTAGLFTAWDPAK----QWDPQGSPQTGLSATLLPHGAPHPAQTLHRSSVPDS-EAFHLGKPDPYDLYEKSRAIYESRQPLPPRT--LTDSTGVEYQEVEVHLLREKTGFGFRILGGDEAVQAVSPEARDKIVIGAIIENSPAERDGRLRPGDELVSVDRMPVGGRPHRYVIDLMHAAARNGQVTLTVRRRVLTQQSQPCEENGGS----ANQNSSPRG---------HAVCPVN-------LPP----------TTDVVIHRKESEGFGFVIISSLNRPETTNTITVPHKIGRIIEGSPADRCGKLKVGDRIMAVNCQSIINMPHADIVKLIKDAGLTVTLHIIPEEDVNGAHSAPTSEKQSPMVAQKHSPQT---------------QSSPATQQSPTMAHPSPPAPHPSPATTQPSPLLVDQSPGAPHGSPPLIQGSVSVSQAGLESMQTGSAMTQAAPVLDPGMTGIQTTIIGSVPVPVPPQLYLHDTRSEVKARQDVKPDICQAAYTDYRQPPVDYRHPPVADYRQPPTMEYRHP------PALIDYRQHSIADYR-PQDYDYFTVELEKSVKGFGFSIRGGREYKMDLFVLRLAEDGPAVRNGRMRVGDQIIEINGESTRDMSHARAIELIKAGGRRVRLLLKRGTGQVPEY--------------------------GMVPTN---------------------------------LSMCMKSDTLASPYFFIMGHSKDTTVP----------------------PPGVLSLQ-----------PPLPCRK-------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "F1Q897-1", "uniprot_id": "F1Q897_DANRE", "id": "F1Q897-1", "name": "Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1", "aln": "MAVVLSTTSNMSKSLKKKSHWTNRVHEVVLSRGPSGDLGFELQGGAENGQ-FPVIGEVKP------DRRKLQQDELLLEVNDTPVAGLTIRDVWAVVRHCKDPVRFKCVKQGGVVDKDLRQYLNLRFQKGSLDHELQQIIRDNLYLRTVPCTTRQPREG--EVPGVDYNFVTVERFVELERSGALLESGTYEDNYYGTPKPPAEPSPLLLNVAEQ----LLPGATPTSQGKRRRNKSVSNMEKAGIEPPEEEEEERPVINGNGVAITPESSEHEDKSTDASGEMAT-----TCPSETSTDAPKEDTEPPKSPPKPDENDELGPLPDNWEMAYTEKGEVYFIDHNTKTTSWLDPRLAKKAK-PPEECKENELPYGWEKIDDPIYGTYYVDHINRRTQFENPVLEAKRRLQHQQQMQSQGLS------------------SLPLPA-VYREKP----------LFTRDPTQLKGSFLSTPLQKSNMGFGFTIIGGD-----EPDEFLQVKSVIPDGPAAQDGKMATGDVIVYINDVCVLGTTHADVVKLFQSVPIGQSVTLVLCRGYPLPYDPEDA-ANTLLSPLGLIDRP--LLVNGRNSYDSYMEYISRTARFVDPLQTT---MVQPHPGDTHLDA----------GPLEDSVSMASS-----GAAGG-ELLTINMVKGADGFGFTIADSNGGQRVKQILEAQGCPGLCEGDLIVEINQQPALTLSHTQVVELLKECPIGTEATLVIQRGG-TGHFSPWKTTKQVLEHWDPLSSPTTSLSVHALPHSAPYLH--------WPSGPEFDLAKPDPYDLYEKSRAIYENRQPGLPRASLPADPS-AEFQEVEVHLRRQKSGFGFRILGGEEPGQPVSPKAQEKILIGAIIEKSPADKDGRLRPGDELISVDGIVVAGKPHRYVIDLMHGAARTGQVKLTVRRRVQPT-GEPFPENGRSPG--STQHSSPRSDFNSRMFCNNSAPSQNSAPSTTGSSPPDTAANQNAQPNDVSIQRKETEGFGFVIISSLNRPETAAAAAVPHKIGRIIEGSPADHCGKLKVGDRILAVNNQSIVNMPHADIVKLIKDAGLSVTLRIIPQEETNSTPSAGSSEKQSPMAQPSPVCQPNTVNQTGAAPLANSNAQQNSAPQPSPIKQPISEAQPSLVTQNSPAN------------------------------------------------HPSSVTQQNPQTQPVQTYSHDSSYRSEVKARQDVKPDIRQP-FTDYRQPPVDYRHPPVADYRQPPTLDYRHPPLLDYRPLPADPRTFPLPDYRMPQDFDFFTVELEKGMKGFGFSIRGGREYKMDLFVLRLAEDGPAIRNGRMRVGDQIIEINGESTRDMTHARAIELIKSGGRRVRLLLKRGTGQVPEYADSPAPWDAHPTASPSLSEVAPP-LDSLSNPSASSHVNPPTDPPHTSSLEAVG------------PDSCQGPRGSESRALEQASVGKRSALAG----GVGGGTKQREGSRTNRRSSGGKGQQQYLDEFAGEPKSHKSSRAKSKERRRERSSTPSRKRDSPKTSLTDTSMNGGNGCLDGSNSQQGPLVPFKALPKEPEKGQMSQESNPSHNSKISSAAGRKATVSPGPWKIPGTDKLPSTLRSATSTISR", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9W2L2-1", "uniprot_id": "Q9W2L2_DROME", "id": "Q9W2L2-1", "name": "", "aln": "----------------------MPIITATTTSTAGGGAGVAARGVATAKSPTDYLMLQQQQQQQQQQQQHFNSNHFYQQQQPQQLAPLNASHQHQHSHPHPHPHPVAAATSFATFNGNSNLNSSLANGSSRKFNCSRDNVDDGGDAGEMAAASQTLSSAGTDVVGNGSGHGNGTVTGNGEKSGGLAPPGGHHLRPPPPPALKKSASAVIGNSASREDVASLSGTSSLNSQMSVHNQFISGLPSNGIGSNGVHGGAATGRGGPPNSILKGSKENLLQNTYYNGETGDSSLG--------SECGVGDVQHQNHESHDDPGDGLGPLPPKWETAYTERGELYFIDHNTGTSHWLDPRLSKYQKKSLEDCCEDELPYGWEKIEDSMYGMYFIDHVNRRTQYENPVLEAKRRAAEQSQQQQQMQQQQQQMQEQRSKTPTALSETMPTEAAEAHEQEEDESPMKLPYKFTRNPAELQGQRINTTLLKSSRGLGFTIVGSDGSAGGDVEEFLQIKTVVPNGPAWLDGQLQTGDVLVYVNDTCVLGYTHHDMVNIFQSILPGERAALEVCRGYPLPFDPNDP-NTEVVTTMAVDGRE--SDKQRRLNMDGNYNFLDLSGEGAKKTSGS----------------------------GSGFILMKKP-----------EIYTFSIMKGSMGFGFTIADSACGQIVKKILDRNCCTQLMEGDVLLEINGLNVRNKPHFYVVELLKECSQTTPTAVKIQRTP------PDPPANNTLAQLNQVGN-VAKLRKNFVGSGLFRSKTPTADLYSTQVKEVLPMRPKTPLVDTRRSRVQIQS-----PNNEVDDEGDGAAAAERKPLQLQTQGKSNSSLQELDDIPYMDPYPKISRLSERLAEVTLQGDANGGIYGMPPSMQPLPLPLAHHESCYCYDCQAQRYRPGYFVQAQQAAMSGTTGQYSPLQTAHLQNERIQRRVNELLSDRRRVGFANLDPPQQ----MQHSPSWRNGALLDVSEDADQCELTEVTLERQALGFGFRIVGGTEEGSQVTVGHIVPGGAADQDQRINTGDEILSIDGINVLNSSHHKVVSLVGESALRGQVTMILRR----------------------------------------------------------------------------------------------------------------------------------------------------------------------RRTPLLQQAPVSTQLRR----------------------------------YPYDVIVSRHENEGFGFVIISSSNHYYGSTIGKLIPGSPADRCGELKVGDRIVAVNRIEIAGMSHGDVVNLIKESGLHVRLTIGVPLKEGGPS---------------------PGGSS---------------------------------------VGVSSNTPLQASPSLLKAQLSHQQQLP--------------------QQHLQQAQLNHHHQHLEMPMSMPVPGHGSYLERPSNNISATLALHQQPQL---------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : * *. :* * . : : . :: .:.: : : :* *. . : .* . .... . .: : . .* .. : :: : *. :..::: .. :* * . . . : *:**.* .* :. . .* ..:. : * :.: *.*: . . :*: ::.: . .* . . . .* : *.*: :.: .*: .: : : : : .: ..** :** ****:**:******* *: ******:* * . *:* *:*********:*.:** *::**:*****:*********: .:. : * : :*: ***:.::*:* :.* * **. *:****:*.* : :****:*:*:*:*** *.:: ****:**:*: **** ** *:*::***: *: . * :*******:**:*. . :..:.: : : * . : :::. :.. . .. : : .. *: ::.: **: ********* ** **::*: : *. * ***:::*** * **::**:*. : ::: *:* . ..: : : .. : * : . : * .:**. :. *. : * . : : . : : . : .: :* : : : :. : * * * * . : : : .: : :. . . : .* . *. . : :. * .:*:*: *..**: :::.**.*:::: .::* .* .:*.*: ::.* : :* .. *:.*: : * : : : : .: .: :**** * .. :: . : :* ..** * *.::***:*: :* . .*:*. .::*** .* :*** : : . . . : . . : ", "identical_positions": 232, "similar_positions": 336, "identity": "14.0%" }, { "cls_id": "homologset.agr.MGI:1354954", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9JM14-1", "uniprot_id": "NT5C_MOUSE", "id": "Q9JM14-1", "name": "5'(3')-deoxyribonucleotidase, cytosolic type", "aln": "-----------------------------------------------------------MAVKRPVRVLVDMDGVLADFESGLLQGFRRRFPEEPHVPLEQRRGFLANEQYGALRPDLAEKVASVYESPGFFLNLEPIPGALDALREMNDMKDTEVFICTTPLLKYDHCVGEKYRWVEQNLGPEFVERIILTRDKTVVMGDLLIDDKDNIQGLEETPSWEHILFTCCHNQHLALPPTRRRLLSWSDNWRGIIESKRASL---", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D3ZWR1-1", "uniprot_id": "D3ZWR1_RAT", "id": "D3ZWR1-1", "name": "", "aln": "MLHRSCSPSRDAMSSWVPSWSLMQMIRVGPAHTLVPEACFRVWHPRCLLRCSAETPGVAMAVKRPVRVLVDMDGVLADFESGLLQGFRRRFPGEPHVPLEQRRGFLASEQYGALRPDLAEKVASVYEAPGFFLNLEPIPGALDALREMNAMQDTDVFICTTPLRKYDHCVGEKYRWVEQNLGPQFVERIILTRDKTVVMGDLLIDDKDNIQGLEETPSWEHILFTCCHNQHLALPPTRRRLLSWSDDWRGIIESKRASL---", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8TCD5-1", "uniprot_id": "NT5C_HUMAN", "id": "Q8TCD5-1", "name": "5'(3')-deoxyribonucleotidase, cytosolic type", "aln": "-------------------------------------------------------------MARSVRVLVDMDGVLADFEAGLLRGFRRRFPEEPHVPLEQRRGFLAREQYRALRPDLADKVASVYEAPGFFLDLEPIPGALDAVREMNDLPDTQVFICTSPLLKYHHCVGEKYRWVEQHLGPQFVERIILTRDKTVVLGDLLIDDKDTVRGQEETPSWEHILFTCCHNRHLVLPPTRRRLLSWSDNWREILDSKRGAAQRE", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : *.***************:***:******* ************** *** *******:*******:*****:**********:**** : **:*****:** **.************:***:**************:*********.::* ****************:**.*************:** *::***.: ", "identical_positions": 163, "similar_positions": 25, "identity": "62.21%" }, { "cls_id": "homologset.agr.MGI:1354956", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9JKX3-1", "uniprot_id": "TFR2_MOUSE", "id": "Q9JKX3-1", "name": "Transferrin receptor protein 2", "aln": "MEQRWGLLRRVQQWSPRPSQTIYRRVEGPQLEHLEEE-----------DREEGAELPAQFCPMELKGPEHLGSCPGRSIPIPWAAAG--------RKAAPYLVLITLLIFTGAFLLGYVA--------FRGSCQACGDSVLVVDEDVNPE---DSGRTTLYWSDLQAMFLRFLGEGRMEDTIRLTSLRERVAGSARMATLVQDILDKLSRQKLDHVWTDTHYVGLQFPDPAHANTLHWVDADGSVQEQLPLEDPEVYCPYSATGNATG-KLVYAHYGRSEDLQDLKAKGVELAG-SLLLVRVGITSFAQKVAVAQDFGAQGVLIYPDPSDFSQDPHKPGLSSHQAVYGHVHLGTGDPYTPGFPSFNQTQFPPVESSGLPSIPAQPISADIADQLLRKLTGPVAPQEWKGHLSGSPYRLGPGPDLRLVVNNHRVSTPISNIFACIEGFAEPDHYVVIGAQRDAWGPGAAKSAVGTAILLELVRTFSSMVSN-GFRPRRSLLFISWDGGDFGSVGATEWLEGYLSVLHLKAVVYVSLDNSVLG--DGKFHAKTSPLLVSLIENILKQVDSPNHSGQTLYEQVALTHPSWDAEVIQPLPMDSSAYSFTAFAGVPAVEFSFMEDDRVYPFLHTKEDTYENLHKMLRG-RLPAVVQAVAQLAGQLLIRLSHDHLLPLDFGRYGDVVLRHIGNLNEFS---GDLKERGLTLQWVYSARGDYIRAAEKLRKEIYSSERNDERLMRMYNVRIMRVEFYFLSQYVSPADSPFRHIFLGQGDHTLGALVDHLRMLRADGSGAASSRLTAGLGFQESR-FRRQLALLTWTLQGAANALSGDVWNIDNNF---", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "B2GUY2-1", "uniprot_id": "TFR2_RAT", "id": "B2GUY2-1", "name": "Transferrin receptor protein 2", "aln": "MEQRWGLLRKVQQWSPRPSQTIYRRVEGPQLENLEEE-----------DREEGEELPAQFCPMELKGPERLGSCPGRSIPIPWAAAG--------RKAAPYLVLTTLLIFTGAFLLGYVA--------FRGSCQACGDSVLVVGEDVNSE---DSSRGTLYWSDLQDMFLRFLGEGRMEDTIRLTSLRERVAGSARMATLVQDILDKLSRQKLDHVWTDTHYVGLQFPDPAHPNTLHWVGADGSVQEQLPLEDPEVYCPYSATGNATG-KLVYAHYGRREDLQDLKAKDVELAG-SLLLVRAGITSFAQKVAIAQDFGAHGVLIYPDPADFSQDPHKPGLSSDRAVYGHVHLGTGDPYTPGFPSFNQTQFPPVESSGLPNIPAQPISADVADRLLRKLTGPVAPQEWKGRLSDSPYRLGPGPGLRLVVNNHRTSTPISNIFACIEGFAEPDHYVVIGAQRDAWGPGAAKSAVGTAILLELVRTFSSMVSS-GFRPRRSLLFISWDGGDFGSVGATEWLEGYLSVLHLKAVVYVSLDNSVLG--DGKFHAKTSPLLVSLIENILKQVDSPNHSGQTLYDQVAFTHPSWDAEVIQPLPMDSSAYSFTAFAGVPAVEFSFMEDDRVYPFLHTKEDTYENLHKMLRG-RLPAVVLAVAQLAGQLLIRLSHDHLLPLDFGRYGDVVLRHIGNLNEFS---GDLKARGLTLQWVYSARGDYIRAAEKLRKEIYSSEQSDERLMRMYNVRIMRVEFYFLSQYVSPADSPFRHIFLGQGDHTLGALVEHLRMLRSDGSGAASSGLSPGLGFQESR-FRRQLALLTWTLQGAANALSGDVWNIDNNF---", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9UP52-1", "uniprot_id": "TFR2_HUMAN", "id": "Q9UP52-1", "name": "Transferrin receptor protein 2", "aln": "MERLWGLFQRAQQLSPRSSQTVYQRVEGPRKGHLEEEE---------EDGEEGAETLAHFCPMELRGPEPLGSRPRQPNLIPWAAAG--------RRAAPYLVLTALLIFTGAFLLGYVA--------FRGSCQACGDSVLVVSEDVNYEPDLDFHQGRLYWSDLQAMFLQFLGEGRLEDTIRQTSLRERVAGSAGMAALTQDIRAALSRQKLDHVWTDTHYVGLQFPDPAHPNTLHWVDEAGKVGEQLPLEDPDVYCPYSAIGNVTG-ELVYAHYGRPEDLQDLRARGVDPVG-RLLLVRVGVISFAQKVTNAQDFGAQGVLIYPEPADFSQDPPKPSLSSQQAVYGHVHLGTGDPYTPGFPSFNQTQFPPVASSGLPSIPAQPISADIASRLLRKLKGPVAPQEWQGSLLGSPYHLGPGPRLRLVVNNHRTSTPINNIFGCIEGRSEPDHYVVIGAQRDAWGPGAAKSAVGTAILLELVRTFSSMVSN-GFRPRRSLLFISWDGGDFGSVGSTEWLEGYLSVLHLKAVVYVSLDNAVLG--DDKFHAKTSPLLTSLIESVLKQVDSPNHSGQTLYEQVVFTNPSWDAEVIRPLPMDSSAYSFTAFVGVPAVEFSFMEDDQAYPFLHTKEDTYENLHKVLQG-RLPAVAQAVAQLAGQLLIRLSHDRLLPLDFGRYGDVVLRHIGNLNEFS---GDLKARGLTLQWVYSARGDYIRAAEKLRQEIYSSEERDERLTRMYNVRIMRVEFYFLSQYVSPADSPFRHIFMGRGDHTLGALLDHLRLLRSNSSGTP--GATSSTGFQESR-FRRQLALLTWTLQGAANALSGDVWNIDNNF---", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q08919-1", "uniprot_id": "TRE1_YEAST", "id": "Q08919-1", "name": "Uncharacterized protein TRE1", "aln": "MVNTRGYTTLPNVEEP-----ANNSQDELNSQDFEQA------------IGMPSEPPVYVEEMGMEEPQAPEAFSEKVQRFRMCFENNVVIPVKKNVVDPLAQMISLASEKFDLFLSKIGNVMVMRRIFYIMMMSIIAALIIASDRLPNGKARGSNGSFSDHDLLLQYARKSIDLSKIERDLEYISSMPHMSGTSGDAAIRHYIKESFDKNGIRLAGEEEFMAYSNYPG---NVSLRVYSKDDTEGFDIPLNE-ENFNPMSHNGQLNNIPVIYANKASLDDMASMQDQGLLNG--DFILLVHYGDYVFQQMLTAQEYGAKAIIFISEPYQDNKD------VIQMKSVALPQYGTGDALTPEWEGSIRDPIDATEAKCLPKIPSIPISANQGDKILAILSDTGVKFSNN----LFSGSLNDCRLDLLVQTAIRERHPVHDIVGKIEGSEQAGRAIVIAAPRNSASYGTMYPSFGTVVLLSLIQLYQEMVYKFDWKPLRNIYFISFGGSEFNEAGATELMEKRTEALKSEIYTIIDVGQIGI-----WDDSNN---LEIQCHPLLVDLFQKNMTSRKFNVKVDNVH-------------QFGDWTPYLAQGIPVAIISSPGVMNREHPIYTVEDKFDFIKDKLRDKKKGEVLSEIMLYLVEKSLELIDDPFIPFSISNYVDFLSTTLKDLQKECPDTVNFDEVFLGTTLWENTKLQFEKWKSEWTELMYGAGTYIEPTIIAINRWSWNYLLSLIGVTQCLEEGLMDRTFYKNVIFGPKLWVD----KGDPLRSWTFPEIRDTIAIKDWSSVQVQANTLGTILQNTARYFLENKNLHGINTNEF", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "Q08693-1", "uniprot_id": "TRE2_YEAST", "id": "Q08693-1", "name": "Putative zinc metalloprotease TRE2", "aln": "MRSSYQPVSTTNFEHENAIPTASSSHNLLMSQRFDDSPPSSNDNSIETNITPPPEPPSY--EFDIEDPHDDLHKRTHLQRVSIGFQEKILEPLMENIIHPLLQISKFVPDKADYYLSKIGNPFILRRFFYIIFMSFIAYYVLSSGYLFNEKASGSKGMFSQHDILFEYAKKSVDLAKFERDLEYISSMPHGSGTKGDAAIYRYIQESFDNNGLKLVKEMGYSVYSNYPG---NVSISYYD-NKNEKHDLELSK-ENFNPLSSNGKLSKVSLIYGGKGTTYDLQHLKDSKTIEDGKDYVLLLQYDKLVSQQVLIAEKFGAKAVIFISEPYGENID------VVQSKPVGLPQYSTGDASGLNWDGSPVEEKDHKFWR-QTHIPTIPISTRQGKELLSRLSSGGVTVDDGNSDRSNSGKMGDVLIDVDLQTNVREKHFIPNIVGKIEGREQSDKAIIIAASRNSINFGTTYPNFGTAALLSIVQLFQEVKYKFGWKPLRNIYFISFGGTEFNYAGSSELVEQRLTPLKDEIYSLIDISQLGIPFAEKYENGKTRGELSIETHPLLKKFFNRNAHG-NFDISVDNVQ-------------HYGDWTPFLANGIPVSVISSDSTRNRDTPTETSEDKFERVEKILEDEQNQQSVKDLLVYLLHISMELIDDPLLHFDIISYVEDIDERLQRLEQAYPEKLNFTSIIKGLLFWKKIGSEWASWTQGWENIVWSHGDGIEPSLLSINRWTWNKKLTNIGRRTCSPAGLPNRSFYKNVLFGPTLIQEDKSKNGGNVDFWTFPGVMDAIYDDDWKRAQEQIDLIGKVLHQSAALFVEETNDIGYK----", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* : : ::: * : :. *. : . . * : : . *. :. * : :: . : . . * : :. .::* :. * : :*: *:: : * :..: : . . . ::*. :: . . :: *.. : : * * *: . ::*. . *: :: :*: . *:: *:.:**:.::: .:* . * . . : .***. : . . **: ***: ...:* *.. . . . :. : . * : :*.. *** :..: ::*.* *:: . *: . .**. **.::: :..: . .::* *.: ***:.* :*. .*::* :* *: : :.:.: : ..:. * . :* .. . * . .: .* .: . . :: *:*. :* . * **.:: :.. *.. : : . :.* .* :: :.: * : : : *:: :: . :: . : ::. * * . : :. . . : * . . : . .: : * : *: :* : : . : ", "identical_positions": 81, "similar_positions": 234, "identity": "9.63%" }, { "cls_id": "homologset.agr.MGI:1354958", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D4A6E6-1", "uniprot_id": "D4A6E6_RAT", "id": "D4A6E6-1", "name": "Heparan-sulfate 6-O-sulfotransferase", "aln": "--------------------MRRRRAGGRTMVERA-------------------------------SKFVLVVAGS---ACFMLILYQYAGPGLS-LGAPGGRAP-PDDLDLFPT----PDPHYEKKYYFPVRELERSLRFDMKGDDVIVFLHIQKTGGTTFGRHLVQNVRLEVPCDCRPGQKKCTCYRPNRRETWLFSRFSTGWSCGLHADWTELTNCVPGVLDRRDPAGLRSPRKFYYITLLRDPVSRYLSEWRHVQRGATWKTSLHMCDGRTPTPEELPPCYEGTDWSGCTLQEFMDCPYNLANNRQVRMLADLSLVGCYNLSFIPESKRAQLLLESAKKNLRGMAFFGLTEFQRKTQYLFERTFNLKFIRPFMQYNSTRAGG--VEVDEDTIRHIEELNDLDMQLYDYAKDLFQQRYQYKRQLER-REQRLRNRE--ERLLHRSKEALPREDT---EEPGRVPTEDYMSHIIEKW", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9QYK5-1", "uniprot_id": "H6ST1_MOUSE", "id": "Q9QYK5-1", "name": "Heparan-sulfate 6-O-sulfotransferase 1", "aln": "--------------------MRRRRAGGRTMVERA-------------------------------SKFVLVVAGS---ACFMLILYQYAGPGLS-LGAPGGRVP-PDDLDLFPT----PDPHYEKKYYFPVRELERSLRFDMKGDDVIVFLHIQKTGGTTFGRHLVQNVRLEVPCDCRPGQKKCTCYRPNRRETWLFSRFSTGWSCGLHADWTELTNCVPGVLDRRDPAGLRSPRKFYYITLLRDPVSRYLSEWRHVQRGATWKTSLHMCDGRTPTPEELPPCYEGTDWSGCTLQEFMDCPYNLANNRQVRMLADLSLVGCYNLSFIPESKRAQLLLESAKKNLRGMAFFGLTEFQRKTQYLFERTFNLKFIRPFMQYNSTRAGG--VEVDEDTIRHIEELNDLDMQLYDYAKDLFQQRYQYKRQLER-REQRLRNRE--ERLLHRSKEALPREDP---EEPGRVPTEDYMSHIIEKW", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O60243-1", "uniprot_id": "H6ST1_HUMAN", "id": "O60243-1", "name": "Heparan-sulfate 6-O-sulfotransferase 1", "aln": "--------------------MRRRRAGGRTMVERA-------------------------------SKFVLVVAGS---VCFMLILYQYAGPGLS-LGAPGGRAP-PDDLDLFPT----PDPHYEKKYYFPVRELERSLRFDMKGDDVIVFLHIQKTGGTTFGRHLVQNVRLEVPCDCRPGQKKCTCYRPNRRETWLFSRFSTGWSCGLHADWTELTNCVPGVLDRRDSAALRTPRKFYYITLLRDPVSRYLSEWRHVQRGATWKTSLHMCDGRTPTPEELPPCYEGTDWSGCTLQEFMDCPYNLANNRQVRMLADLSLVGCYNLSFIPEGKRAQLLLESAKKNLRGMAFFGLTEFQRKTQYLFERTFNLKFIRPFMQYNSTRAGG--VEVDEDTIRRIEELNDLDMQLYDYAKDLFQQRYQYKRQLER-REQRLRSRE--ERLLHRAKEALPREDA---DEPGRVPTEDYMSHIIEKW", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q56UJ5-1", "uniprot_id": "H6S1A_DANRE", "id": "Q56UJ5-1", "name": "Heparan-sulfate 6-O-sulfotransferase 1-A", "aln": "----------------------MNLLTGRNMVERS-------------------------------SKFLFIVVGS---VLFMLILYQYVAPGMMNFGSPHGYML-EDDADLFPT----PDPHYVKKFYFPIRDLERTVDFEIKGDDVIVFLHIQKTGGTTFGRHLVQNVRLEVPCDCRPGQKKCTCYRPNRKETWLFSRFSTGWSCGLHADWTELTNCVPGVLNKKE-SRMKNQRKFYYITLLRDPVSRYLSEWRHVQRGATWKTSLHMCDGRTPTPEELPPCYEGTDWSGCTLQQFMDCPYNLANNRQVRMLADLSLVGCYNMSFIPEKKRAQVLLESAKKNLRDMAFFGLTEFQRKTQYLFERTFRLKFIRPFMQYNSTRAAG--VDLDNDTIQRIEELNDLDMQLYDYARDLFQQRYMYKRQLER-REQRLKNQPLFPFRRTSSSDSTFRDDAPESEG-SRLPTEDYMNHIINRW", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0MGZ5-1", "uniprot_id": "H6S1B_DANRE", "id": "A0MGZ5-1", "name": "Heparan-sulfate 6-O-sulfotransferase 1-B", "aln": "----------------------MN-DTERNMVERT-------------------------------SKFLLIVVGS---VFFMLILYQYVAPGVINFGSPHGYLLGEEDMTIFPT----PDPHYVKKYYFPIKDLERKIDFEIKGEDVIVFLHIQKTGGTTFGRHLVQNVRLELPCDCRPGQKKCTCYRPNRKETWLFSRFSTGWSCGLHADWTELTNCVPGVLNKRE-SKSKKMRKFYYITLLRDPVSRYLSEWRHVQRGATWKTSLHMCDGRTPTPEELPPCYEGTDWSGCTLQQFMDCPYNLANNRQVRMLADLSLVGCYNLSTVPEKRRSQLLLESAKKNLRDMAFYGLTEFQRKTQYLFERTFHLKFIRPFMQYNSTRAAG--VDLDNDTIQRIEELNDLDMKLYDYAKDLFQQRYQYKHMLDR-REQRL-------LRGHASFHSPFREDGAGGEGTARLPTEDYMNHIINGW", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VDR6-1", "uniprot_id": "Q9VDR6_DROME", "id": "Q9VDR6-1", "name": "Heparan-sulfate 6-O-sulfotransferase", "aln": "MPGDMHKNVSVQVDSDFALLLPSGVYEIKKMEPRSKIRTIIVFCLFLAIAGIIGFGYFCQDQVCALSKRAVILQSSDILAYNELPLHQANSINGNANGNSNGNGNSVGGITAMASKSSAPQNIIANAGLSYEDVLNDDFQFDMDGHDVMVFLHIQKTGGTSFGRHLVRDLDLKRPCECQRQRKRCYCFRPHRNENWLFSRYSTGWKCGLHADWTELTSCVDVELDKNE--GETAKRRYFYISLLRQPIARYMSEYRHVRRGATWKGSRHWCLGRQATAAELPACYKGKDWLDVDLDQFAGCESNLAANRQTRMLADLALVGCYNKSSMPAHERDRVMLASAKRNLAAMAYFGLTEYQKMSQYIFEETFNLRFAIPFEQHNTTISATAVQNLRPDQKRRIEKLNSLDIELYAFAKTLLFQRFEHLKAKDTNFEQRYANLG---NIYFKQGVTEFNWDS---NVEDGLSTDH---------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :.* *: ** .:: .* . * *:* . . * . * . :.: *: : *: . *::.*.**:***********:******::: *: **:*: :*:* *:**:*.*.*****:****.***********.** *::.: *:::**:***:*::**:**:***:****** * * * ** .*. ***.**:*.** . *::* .* *** ***.******:****** * :* .* :::* ***:** **::****:*: :**:**.**.*:* ** *:*:* :. :: * ::**:**.**::** :*: *: **: : : : *** : . * : :.*:. ", "identical_positions": 169, "similar_positions": 107, "identity": "35.28%" }, { "cls_id": "homologset.agr.MGI:1354959", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZEK5-1", "uniprot_id": "D3ZEK5_RAT", "id": "D3ZEK5-1", "name": "Heparan-sulfate 6-O-sulfotransferase", "aln": "MALPAFAARALGPPLQPEQGAPARTTCPRRHSRVEAELAASRPGSVAASVRAGPPRGVSLGFNSPPLQDKPPKTFSSLAGALRAPLFALLPRGRRRRMHDLRRRWDLGSLCRALLTRGLAAVGHSLKHVLSAIFSKIFGPLASVGNMDEKSN--KLLLALVMLFLFAVIVLQYVCPGTECQLLRLQAFSSPVP--------------DPYRSEDESSARFVPRYNFSRGDLLR-KVDFDIKGDDLIVFLHIQKTGGTTFGRHLVRNIQLEQPCECRVGQKKCTCHRPGKRETWLFSRFSTGWSCGLHADWTELTSCVPAVVDGK--RDARLRPSRWRIFQILDAASKDRWGSSNFNSGANSPSSTKPRSTTKSGKNFHYITILRDPVSRYLSEWRHVQRGATWKASLHVCDGRPPTSEELPSCYTGDDWSGCPLKEFMDCPYNLANNRQVRMLSDLTLVGCYNLSVMPEKQRNKVLLESAKSNLKHMAFFGLTEFQRKTQYLFEKTFNMNFISPFTQYNTTRASS--VEINEEIQKRIEGLNFLDMELYSYAKDLFLQRYQFMRQKEHQDARRKRQEQRKFLKGRFLQTHFQSQSQSQGQSQGQSQGQSQGPGQNLSQNPNPNPNQNLTQNLSQNLTQSSNPNLTQRENHGSQKQGSGQEQSDSSTSNGTNDYIGSVETWR", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q80UW0-1", "uniprot_id": "H6ST2_MOUSE", "id": "Q80UW0-1", "name": "Heparan-sulfate 6-O-sulfotransferase 2", "aln": "MALPAFAARALGPPLQPEQGAPARTTCPRRHSRVEAELAASRPGSVAASVRAGPPRGVSLGFNSPPLQDKPPKAFSSLAGALRAPLFALLPRGRRRRMHDLRRRWDLGSLCRALLTRGLAAVGHSLKHVLSAIFSKIFGPLASVGNMDEKSN--KLLLALVMLFLFAVIVLQYVCPGTECQLLRLQAFSSPVP--------------DPYRSEDESSARFVPRYNFSRGDLLR-KVDFDIKGDDLIVFLHIQKTGGTTFGRHLVRNIQLEQPCECRVGQKKCTCHRPGKRETWLFSRFSTGWSCGLHADWTELTSCVPAVVDGK--RDARLRPS----------------------------------------RNFHYITILRDPVSRYLSEWRHVQRGATWKASLHVCDGRPPTSEELPSCYTGDDWSGCPLKEFMDCPYNLANNRQVRMLSDLTLVGCYNLSVMPEKQRNKVLLESAKSNLKHMAFFGLTEFQRKTQYLFEKTFNMNFISPFTQYNTTRASS--VEINEEIQKRIEGLNFLDMELYSYAKDLFLQRYQFMRQKEHQDARRKRQEQRKFLKGRFLQTHFQSQSQ--GQSQ------SQSPGQNLSQNPNPNPNQNLTQNLSHNLTPSSNPNSTQRENRGSQKQGSGQGQGDSGTSNGTNDYIGSVETWR", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q96MM7-1", "uniprot_id": "H6ST2_HUMAN", "id": "Q96MM7-1", "name": "Heparan-sulfate 6-O-sulfotransferase 2", "aln": "MALPACAVREFEPPRQPERGAPVRTTCPRRHSRVEAELAASRPGSVAASVRAGPPRGVSHGFHTRPLLDKPRKASSSLAGAACAPLFALLSRGRRRRMHVLRRRWDLGSLCRALLTRGLAALGHSLKHVLGAIFSKIFGPMASVGNMDEKSN--KLLLALVMLFLFAVIVLQYVCPGTECQLLRLQAFSSPVP--------------DPYRSEDESSARFVPRYNFTRGDLLR-KVDFDIKGDDLIVFLHIQKTGGTTFGRHLVRNIQLEQPCECRVGQKKCTCHRPGKRETWLFSRFSTGWSCGLHADWTELTSCVPSVVDGK--RDARLRPS----------------------------------------RNFHYITILRDPVSRYLSEWRHVQRGATWKASLHVCDGRPPTSEELPSCYTGDDWSGCPLKEFMDCPYNLANNRQVRMLSDLTLVGCYNLSVMPEKQRNKVLLESAKSNLKHMAFFGLTEFQRKTQYLFEKTFNMNFISPFTQYNTTRASS--VEINEEIQKRIEGLNFLDMELYSYAKDLFLQRYQFMRQKEHQEARRKRQEQRKFLKGRLLQTHFQSQGQ--GQSQ--------NPNQNQSQNPNPNANQNLTQNLMQNLTQS----LSQKENRESPKQNSGKEQNDN-TSNGTNDYIGSVEKWR", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q800H9-1", "uniprot_id": "H6ST2_DANRE", "id": "Q800H9-1", "name": "Heparan-sulfate 6-O-sulfotransferase 2", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------MDGKSNYSRLLIALLMILFFGGIVLQYICSTSDWQLLHLASLSSRLGSRAPGDRLNGAGAGDPYSSEDGALVRFVPRFNFTTKDLSR-AVDFHIKGDDVIVFLHIQKTGGTTFGRHLVRNIQLERPCECHAGQKKCTCYRPGKRDTWLFSRFSTGWSCGLHADWTELTNCVPSFMSNRESQERRMTPS----------------------------------------RNYYYITILRDPVWRYLSEWRHVQRGATWKASKHMCDGRLPTLTELPSCYPGDDWSGCSLEEFMVCPYNLANNRQTRMLADLSLVGCYNLTVMSENQRWAMLLESAKRNLRNMAFFGLTEYQRKTQYLFEHTFRLSFIAPFTQLNGTRAAS--VEVEPETQRRIRELNQWDVELYEYARDLFLQRFQFARQQERREARQRRIQERRKLR-AKVKSWLGVTGK--------------AVFKPTKEPPMTEQSPAFAEEKQADAERT-----LESETEG-QVEENWLEEDDG---EIMLDYLENVEQWR", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VDR6-1", "uniprot_id": "Q9VDR6_DROME", "id": "Q9VDR6-1", "name": "Heparan-sulfate 6-O-sulfotransferase", "aln": "----------------------------------------------------------------------MPGDMHKNVSVQVDSDFALLLPSGVYEIKKMEPRSKIRTIIVFCLFLAIAGIIG-------------FGYFCQDQVCALSKR--AVILQSSDILAYNELPLHQANSINGNANGNSNGNGNSVG------------GITAMASKSSAPQNIIANAGLSYEDVLNDDFQFDMDGHDVMVFLHIQKTGGTSFGRHLVRDLDLKRPCECQRQRKRCYCFRPHRNENWLFSRYSTGWKCGLHADWTELTSCVDVELDKNEGETAK--------------------------------------------RRYFYISLLRQPIARYMSEYRHVRRGATWKGSRHWCLGRQATAAELPACYKGKDWLDVDLDQFAGCESNLAANRQTRMLADLALVGCYNKSSMPAHERDRVMLASAKRNLAAMAYFGLTEYQKMSQYIFEETFNLRFAIPFEQHNTTISATAVQNLRPDQKRRIEKLNSLDIELYAFAKTLLFQRFEHLKAKDTNFEQRYANLGNIYFKQGVTEFNWD-----------------------------SNVEDGLSTDH-------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ... ::: :: : : *: . . . . .. : . *:. : .::.. .:: *: . .:*.:.*.*::***********:*******:::*::****: :*:* *.** :.:.*****:****.***********.** :. . . : :.:.**::**:*: **:**:***:******.* * * ** .* ***:** *.** . *.:* * *** ***.***:**:****** : *. ::* ::* *** ** **:*****:*: :**:**.**.: * ** * * * ::: ::. : ::**. ** *:*** :*: *::**::. : :: . :: . :: : .: . :: : ", "identical_positions": 148, "similar_positions": 131, "identity": "21.73%" }, { "cls_id": "homologset.agr.MGI:1354960", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I5ZN51-1", "uniprot_id": "A0A8I5ZN51_RAT", "id": "A0A8I5ZN51-1", "name": "Heparan-sulfate 6-O-sulfotransferase", "aln": "MDERFNKWLLTPVLTLLFVVIMY-QYVSPSCSSSCTNFGEQLRSGEARPPAVPSPARRAQAPPDEWERRPQLPPPPRGPPEGSRGVAAPEDEDEDPGDPEE-EEEEEEE-PDPEAPENGSLPRFVPRFNFTLKD-LTRFVDFNIKGRDVIVFLHIQKTGGTTFGRHLVKNIRLEQPCSCKAGQKKCTCHRPGKKETWLFSRFSTGWSCGLHADWTELTNCVPAIMEKKDCPRNHSHTRNFYYITMLRDPVSRYLSEWKHVQRGATWKTSLHMCDGRSPTPDELPTCYPGDDWSGVSLREFMDCSYNLANNRQVRMLADLSLVGCYNLTFMNESERNTILLQSAKNNLKNMAFFGLTEFQRKTQFLFERTFNLKFISPFTQFNITRASN--VDINDGARQHIEELNFLDMQLYEYAKDLFQQRYHHTKQLEHQRDRQKRREERRLHREHRAHR--WPKEDRAIEGTV--------TEDYNSQVVRW", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9QYK4-1", "uniprot_id": "H6ST3_MOUSE", "id": "Q9QYK4-1", "name": "Heparan-sulfate 6-O-sulfotransferase 3", "aln": "MDERFNKWLLTPVLTLLFVVIMY-QYVSPSCTSSCTNFGEQLRSGEARPPAVPSPARRAQAPLDEWERRPQLPPPPRGPPEGSRGVAAPEDEDEDPGDPEE-EEEEEEEEPDPEAPENGSLPRFVPRFNFTLKD-LTRFVDFNIKGRDVIVFLHIQKTGGTTFGRHLVKNIRLEQPCSCKAGQKKCTCHRPGKKETWLFSRFSTGWSCGLHADWTELTNCVPAIMEKKDCPRNHSHTRNFYYITMLRDPVSRYLSEWKHVQRGATWKTSLHMCDGRSPTPDELPTCYPGDDWSGVSLREFMDCSYNLANNRQVRMLADLSLVGCYNLTFMNESERNTILLQSAKNNLKNMAFFGLTEFQRKTQFLFERTFNLKFISPFTQFNITRASN--VDINDGARQHIEELNFLDMQLYEYAKDLFQQRYHHTKQLEHQRDRQKRREERRLQREHRAHR--WPKEDRAMEGTV--------TEDYNSQVVRW", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8IZP7-1", "uniprot_id": "H6ST3_HUMAN", "id": "Q8IZP7-1", "name": "Heparan-sulfate 6-O-sulfotransferase 3", "aln": "MDERFNKWLLTPVLTLLFVVIMY-QYVSPSCTSSCTNFGEQPRAGEAGPPAVPGPARRAQAPPEEWERRPQLPPPPRGPPEGPRGAAAPEEEDEEPGDPREGEEEEEEDEPDPEAPENGSLPRFVPRFNFSLKD-LTRFVDFNIKGRDVIVFLHIQKTGGTTFGRHLVKNIRLEQPCSCKAGQKKCTCHRPGKKETWLFSRFSTGWSCGLHADWTELTNCVPAIMEKKDCPRNHSHTRNFYYITMLRDPVSRYLSEWKHVQRGATWKTSLHMCDGRSPTPDELPTCYPGDDWSGVSLREFMDCTYNLANNRQVRMLADLSLVGCYNLTFMNESERNTILLQSAKNNLKNMAFFGLTEFQRKTQFLFERTFNLKFISPFTQFNITRASN--VEINEGARQRIEDLNFLDMQLYEYAKDLFQQRYHHTKQLEHQRDRQKRREERRLQREHRDHQ--WPKEDGAAEGTV--------TEDYNSQVVRW", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0MGZ7-1", "uniprot_id": "H6S3B_DANRE", "id": "A0MGZ7-1", "name": "Heparan-sulfate 6-O-sulfotransferase 3-B", "aln": "MNDKPNKWIFIPILAILFVMIGY-QYVCPAGGQACH-----FRTG------------------DKLVRIAPLATP----------------------DPTTDDLYREQD------PEEDNPPKCASKFNFTERD-LTRDVDFNIKGDDVIVFLHIQKTGGTTFGRHLVRNIRLEQPCDCKAGQKKCTCHRPGKQESWLFSRFSTGWSCGLHADWTELTNCVPVIMDKRQPPK---RKRNFYYITMLRDPVSRYLSEWKHVQRGATWKTSLHMCDGRSPTQDELPTCYNGDDWSGVTLHDFMDCPSNLANNRQVRMLADLSLVGCYNLSTMNESERNPILLASAKSNLKNMAFYGLTEFQRKTQYLFERTFHLRFISAFTQINSTRAAN--VELRDDMRSRIEQLNMLDMQLYEFAKDLFLQRYQFVRQRERQEERLKRREERRWIRERRVNQSKEPIVENQTRVTT--------TEDYASQVVRW", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "F1Q9K7-1", "uniprot_id": "F1Q9K7_DANRE", "id": "F1Q9K7-1", "name": "Heparan-sulfate 6-O-sulfotransferase", "aln": "MDDKSNKLLLVPVLTVLFVMIGY-QYICPAGSTSCR-----FGNG---------------------EGFPFSKYP--------------------------ADVKREEN-------EEDASFRFQSKFNFTRDD-LERHVDFDIKGNDVIVFLHIQKTGGTTFGRHLVRNIHLERPCDCRSGQKKCTCHRPGKAESWLFSRFSTGWTCGLHADWTELTNCVPAVMNKK-LKKDALNRRSFYYITLLRDPVSRYLSEWKHVQRGATWKTALHMCDGRPPTPDELPACYSSEDWTGVTLEEFMACSSNLANNRQTRMLADLSLVGCYNLSSMSEERRAELLLSSAKRNLRRMAFFGLTEFQRKTQFLFERTFGLHFIAAFTQINGTRAAG--VTVGTSTRRRIEELNALDMQLYEYARELFLHRIQFCHHQERQEEKKRKRQERRTMKQQKTSA-VWQQEDNRAKDTVGKMEVTGVTEDYSSQVVRW", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VDR6-1", "uniprot_id": "Q9VDR6_DROME", "id": "Q9VDR6-1", "name": "Heparan-sulfate 6-O-sulfotransferase", "aln": "MPGDMHKNVSVQVDSDFALLLPSGVYEIKKMEPRSKIRTIIVFCLFLAIAGIIGFGYFCQDQVCALSKRAVILQSSDILAYNELPLHQANSINGNANGNSNGNGNSVGG-ITAMASKSSAPQNIIANAGLSYEDVLNDDFQFDMDGHDVMVFLHIQKTGGTSFGRHLVRDLDLKRPCECQRQRKRCYCFRPHRNENWLFSRYSTGWKCGLHADWTELTSCVDVELDKN---EGETAKRRYFYISLLRQPIARYMSEYRHVRRGATWKGSRHWCLGRQATAAELPACYKGKDWLDVDLDQFAGCESNLAANRQTRMLADLALVGCYNKSSMPAHERDRVMLASAKRNLAAMAYFGLTEYQKMSQYIFEETFNLRFAIPFEQHNTTISATAVQNLRPDQKRRIEKLNSLDIELYAFAKTLLFQRFEHLKAKDTNFEQRYANLGNIYFKQGVTEF----NWDSNVEDGL--------STDH-------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* :* : : : : ::: * . . . : :.. . .. .:: * * .:*::.* **:***********:******::: *::**.*: :*:* *.** : *.*****:****.***********.** . ::*. . * ::**::**:*::**:**::**:****** : * * ** .* ***:** ..** .* * :* * *** ***.******:****** : * .* ::* *** ** **::****:*: :*::**.** *:* .* * * * :: : . : :**.** **::** :*: *: :* .. : : : :: . . :: : . : *: ", "identical_positions": 149, "similar_positions": 110, "identity": "30.72%" }, { "cls_id": "homologset.agr.MGI:1354961", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P50942-1", "uniprot_id": "INP52_YEAST", "id": "P50942-1", "name": "Polyphosphatidylinositol phosphatase INP52", "aln": "MKILLSKQQTRKIAIVSETHGLVFRPI------NSK----NSRRSTCAVELVPKAELNGNGFRRLSNHEIYGFIGLIEIEGLMFIATITGKSKV---------AQPIPNKTVNKIYAVDFFCLNNSKWDFMDIDSSGYPIVTNDGDFAISSPPSISTHSSRSSLRSSSSRSLNAQEQAPKHPCHELRKLLSNGSFYYSTDFDLT-CTLQKRGFTEHSLSFDDFDREFMWNSFLMDEIITYRDRLDVTAKELLDQRGFLTTVIRGFAETIFSYINRLKVGLTIISRQSWKRAGTRFNARGIDDDGHVANFVETEMIMYSSQYCYAFTQIRGSLPIFWE-QDTSLIS-PKIQITRSVEATQPTFDEHFIRLFKKYGPVHIINLLSTKSSEIQLSRRYKEQLKNSEKMKIGRDVFLTSFDFHRETSQDGFAAASRIIPKIRNTILDAGYFSYDVKEGRLISEQDGVFRTNCLDCLDRTNLIQQTISLAVFKLFLEDFRLVKPSSFIDDNEFVQKVNALWADNGDQISQIYTGTNALKSSYS----RKGKMSFSGALS------DATKSVSRMYINNFVDKGKQQNIDTLLGKLPHQQVVELYDPICEYVNERLLESEEKFTTHSNINLFVGTFNVNGNS-------RRADLSKWLFPIG-----------DKFKPDVVVLGLQEVIELTAGSILNADYTKSSFWETMVTDCLNQY--EEKYLLLRVEQMSSLLILFFARSDRAYNIKEVGGSTKKTGFGGITGNKGAVAIRFDYGATSFCFVNTHLSAGASNIDERRNDYNNIYRNITFPRSKTIPHHDSLFWLGDLNYRITLTNDEVRRELRAQKDGYIDRLLQYDQLTQEINEGVVFQGFKEPTLQFRPTYKYDYGTDNYDTSEKARTPSWTDRIIYKGE-----------------------------NLHPLAYSDAPLKISDHKPVYAAYRANVKFVDEKEKLNLVEKLYAEYKNTHPEALT----------------------------------------------------------------------TGPDELSHARMEKQKESIPLDATVQSAGIKLIDLDDTSSCVSPLLSGPSPQPSVVGPGGLSNVSPDKSKLNVLPPPPPTSRHNKEPSSK-LLSPTKEISIVSVSPRKGESNLP-------------------------------ALERHSTPKPLPPVPALSLSKPVSLQKSSSELQHAKETIDNGKIVPRPCPPIRRKSSTAPDEISTSTKNSGVSTTEDPE------------------------PAKASTKPEKPPVVKKPHYLSVAANKLNTSQEHSIKVSPSNSKSEEELPCKKKSKPKVPAKNPELEKLSVHPLKPCDPN-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "Q12271-1", "uniprot_id": "INP53_YEAST", "id": "Q12271-1", "name": "Polyphosphatidylinositol phosphatase INP53", "aln": "MIIFVSEEPERRLAIVSNLYALVLKPV------GKK----PSDKPLCAIELLQKNDLKKYGFKRLTSHEIFGVIGLIEVNGLLFVGAITGKSKV---------AQPCPGETVNKIFAVDFFCLNDNSWDFIEIDSSGYPVLP-------------------------ETASTEYQDALPKHPCYELKKLLSNGSFYYSSDFDLT-STLQHRGYGQHSLSTDTYEEEYMWNSFLMQEMITYRDHLDTNLKQILDDEGFLTTVIRGFAETFVSYVKKLKVALTIISKQSWKRAGTRFNARGVDDEANVANFVETEFIMYSSQYCYAFTQIRGSIPVFWE-QGTSLIN-PRVQITRSFEATQPVFDKHIMKSVEKYGPVHVVNLLSTKSSEIELSKRYKEHLTHSKKLNFNKDIFLTEFDFHKETSQEGFSGVRKLIPLILDSLLSSGYYSYDVREKKNISEQHGIFRTNCLDCLDRTNLAQQIISLAAFRTFLEDFRLISSNSFIDDDDFVSKHNTLWADHGDQISQIYTGTNALKSSFS----RKGKMSLAGALS------DATKSVSRIYINNFMDKEKQQNIDTLLGRLPYQKAVQLYDPVNEYVSTKLQSMSDKFTSTSNINLLIGSFNVNGAT-------KKVDLSKWLFPIG-----------EKFKPDIVVLGLQEVIELSAGSILNADYSKSSFWENLVGDCLNQY--DDKYLLLRVEQMTSLLILFFVKADKAKYVKQVEGATKKTGFRGMAGNKGAVSIRFEYGATSFCFVNSHLAAGATNVEERRSDYESIVRGITFTRTKMIPHHDSIFWLGDMNYRINLPNEDVRRELLNQEEGYIDKLLHFDQLTLGINSGSVFEGFKEPTLKFRPTYKYDPGTGTYDSSEKERTPSWTDRIIYKGE-----------------------------NLLPLSYSDAPIMISDHRPVYAAYRAKITFVDDKERLSLKKRLFTEYKQEHPEE--------------------------------------------------------------------------PGSLISDLLSLDLDNKSTDGFKSSSESSLLDID-------PIMAQPTAS-SVASSSPVSSASAS-----LQPVRTQNSSQSRTPIKKPVLRPPPPPAHKSVSAP-----------------------------------------APSTSKEKSPTPQTSTASLSSVTKN---IQENKPLAQNRRIPP---PGFSQNILTP---KSTSNLASPMSSKVDLYN-----------------------SASESTRSAQDARQQTPTAFAASR---------DVNGQPEALLGDE--------NPIEPEEKAKLNHMTLDSWQPLTPK-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "Q8CHC4-1", "uniprot_id": "SYNJ1_MOUSE", "id": "Q8CHC4-1", "name": "Polyphosphatidylinositol phosphatase SYNJ1", "aln": "--MAFSKGFRIYHKLDPPPFSLIVETR------HKEECLMFESGAVAVLSSAEKEAIKGTYAKVLDAYGLLGVLRLNLGDTMLHYLVLVTGCMS---------VGKIQESEVFRVTSTEFISLRV--------------------------------------------------DASDEDRISEVRKVLNSGNFYFAWSASG--VSLDLSLNAHRSMQEHTTDNRFFWNQSLHLHLKHYG----------VNCDDWLLRLMCGGVEIRTIYAAHKQAKACLISRLSCERAGTRFNVRGTNDDGHVANFVETEQVIYLDDCVSSFIQIRGSVPLFWE-QPGLQVGSHRVRMSRGFEANAPAFDRHFRTLKDLYGKQIVVNLLGSKEGEHMLSKAFQSHLKAS---EHASDIHMVSFDYHQMVKGGKAEKLHSILKPQVQKFLDYG-FFYFDGSE-VQRCQSGTVRTNCLDCLDRTNSVQAFLGLEMLAKQLEALGLAEKPQLVTR--FQEVFRSMWSVNGDSISKIYAGTGALEGKAK---LKDGARSVTRTIQNNFFDSSKQEAIDVLLLGNTLNSDLADKARALLTTGSLRVSEQTLQSASSKVLKNMCENFYKYSKPKKIRVCVGTWNVNGGKQFRSIAFKNQTLTDWLLDAPKLAGIQEFQDKRSKPTDIFAIGFEEMVELNAGNIVNASTTNQKLWAVELQKTISR---DNKYVLLASEQLVGVCLFVFIRPQHAPFIRDVAVDTVKTGMGGATGNKGAVAIRMLFHTTSLCFVCSHFAAGQSQVKERNEDFVEIARKLSFPMGRMLFSHDYVFWCGDFNYRIDLPNEEVKELIRQQN---WDSLIAGDQLINQKNAGQIFRGFLEGKVTFAPTYKYDLFSEDYDTSEKCRTPAWTDRVLWRRRKWPFDRSAEDLDLLNASFQDESKILYTWTPGTLLHYGRAELKTSDHRPVVALIDIDIFEVEAEERQKIYKEVIAVQGPPDGTVLVSIKSSAQESTFFDDALIDELLRQFAHFGEVILIRFVEDKMWVTFLEGSSALNALSLNGKELLNRTITITLKSPDWIKHLEEEMSLEKISVTLPSSASSTLLGEDAEVAADFDMEGDVDDYSAEVEELLPQHLQPSSSSGLGTSPSSSPRTSPCQSPTVPEYSAPSLPIRPSRAPSRTPGPPSS-----------QGSPVDTQPAA---QKDSSQTLEPKRPPPPRPVAPPARPAPPQRPPPPSGARSPAPARKEFGGVGAPPSPGVARREIEAPKSPGTARKDNIGRNQPS------------PQAGLAG-------PGPAGYGAARPTIPARAGVISAPQSQARVCAGRPTPDSQSKPSETLKGP-AVLPEPLKPQAAFPQQPSLPTPAQKLQDPLVP--------------IAAPTMPPSGPQPNLETP---------PQPPPRSRSSQSLPSDSSPQLQQEQPTG-QVKINGISGVKQEPTLKSDPFEDLS----LSVLAVSKAQPSVQISPVLTPDPKM-LIQLPSASQSQVNPLSSVSCMPTRPPGPEESKSQESMGSSANPFPS-LPCRNPFTDRTAAPGNPFRVQSQESEATSWLSKEEPVPNSPFPPLMPLSHDTSKASSSLGGFEDNFDLQSQSTVKTSNPKGWVTFDEDDNFPTT--GKSKSVCPDLVGNAPASFD-------DDWSKGASVSFCVLPARRPPPPPPPVPLLPPGTTSSAGPSTTLPSKAPSTLDFTER", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q62910-1", "uniprot_id": "SYNJ1_RAT", "id": "Q62910-1", "name": "Polyphosphatidylinositol phosphatase SYNJ1", "aln": "--MAFSKGFRIYHKLDPPPFSLIVETR------HKEECLMFESGAVAVLSSAEKEAIKGTYAKVLDAYGLLGVLRLNLGDTMLHYLVLVTGCMS---------VGKIQESEVFRVTSTEFISLRV--------------------------------------------------DASDEDRISEVRKVLNSGNFYFAWSASG--VSLDLSLNAHRSMQEHTTDNRFFWNQSLHLHLKHYG----------VNCDDWLLRLMCGGVEIRTIYAAHKQAKACLISRLSCERAGTRFNVRGTNDDGHVANFVETEQVIYLDDCVSSFIQIRGSVPLFWE-QPGLQVGSHRVRMSRGFEANAPAFDRHFRTLKDLYGKQIVVNLLGSKEGEHMLSKAFQSHLKAS---EHASDIHMVSFDYHQMVKGGKAEKLHSVLKPQVQKFLDYG-FFYFDGSA-VQRCQSGTVRTNCLDCLDRTNSVQAFLGLEMLAKQLEALGLAEKPQLVTR--FQEVFRSMWSVNGDSISKIYAGTGALEGKAK---LKDGARSVTRTIQNNFFDSSKQEAIDVLLLGNTLNSDLADKARALLTTGSLRVSEQTLQSASSKVLKNMCENFYKYSKPKKIRVCVGTWNVNGGKQFRSIAFKNQTLTDWLLDAPKLAGIQEFQDKRSKPTDIFAIGFEEMVELNAGNIVNASTTNQKLWAVELQKTISR---DNKYVLLASEQLVGVCLFVFIRPQHAPFIRDVAVDTVKTGMGGATGNKGAVAIRMLFHTTSLCFVCSHFAAGQSQVKERNEDFVEIARKLSFPMGRMLFSHDYVFWCGDFNYRIDLPNEEVKELIRQQN---WDSLIAGDQLINQKNAGQIFRGFLEGKVTFAPTYKYDLFSEDYDTSEKCRTPAWTDRVLWRRRKWPFDRSAEDLDLLNASFQDESKILYTWTPGTLLHYGRAELKTSDHRPVVALIDIDIFEVEAEERQKIYKEVIAVQGPPDGTVLVSIKSSAQENTFFDDALIDELLQQFAHFGEVILIRFVEDKMWVTFLEGSSALNVLSLNGKELLNRTITITLKSPDWIKTLEEEMSLEKISVTLPSSTSSTLLGEDAEVSADFDMEGDVDDYSAEVEELLPQHLQPSSSSGLGTSPSSSPRTSPCQSPTAPEYSAPSLPIRPSRAPSRTPGPLSS-----------QGAPVDTQPAA---QKESSQTIEPKRPPPPRPVAPPARPAPPQRPPPPSGARSPAPARKEFGGVGAPPSPGVTRREMEAPKSPGTARKDNIGRNQPS------------PQAGLAG-------PGPSGYGAARPTIPARAGVISAPQSQARVSAGRLTPESQSKPLETSKGP-AVLPEPLKPQAAFPPQPSLPTPAQKLQDPLVP--------------IAAP-MPPSIPQSNLETP---------PLPPPRSRSSQSLPSDSSPQLQQEQPTGQQVKINGACGVKQEPTLKSDPFEDLS----LSVLAVSKAQPSAQISPVLTPDPKM-LIQLPSASQSKVNSLSSVSCMLTMPPVPEQSKSQESVGSSANPFPS-LPTRNPFTDRTAAPGNPFRVQSQESEATSWLSKEEPVSNSPFPPLMPLSHDMSKPSSSLDGFEDNFDLQSQSTVKTSNPKGWVTFDEDEDFPTK--GKSRSVYPDSLGNTAASFD-------DDWSKGTNVSFCVLPARRPPPPPPPVPLLPPGTTSSAGPSTTLSSKASPTLDFTER", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O43426-1", "uniprot_id": "SYNJ1_HUMAN", "id": "O43426-1", "name": "Polyphosphatidylinositol phosphatase SYNJ1", "aln": "--MAFSKGFRIYHKLDPPPFSLIVETR------HKEECLMFESGAVAVLSSAEKEAIKGTYSKVLDAYGLLGVLRLNLGDTMLHYLVLVTGCMS---------VGKIQESEVFRVTSTEFISLRI--------------------------------------------------DSSDEDRISEVRKVLNSGNFYFAWSASG--ISLDLSLNAHRSMQEQTTDNRFFWNQSLHLHLKHYG----------VNCDDWLLRLMCGGVEIRTIYAAHKQAKACLISRLSCERAGTRFNVRGTNDDGHVANFVETEQVVYLDDSVSSFIQIRGSVPLFWE-QPGLQVGSHRVRMSRGFEANAPAFDRHFRTLKNLYGKQIIVNLLGSKEGEHMLSKAFQSHLKAS---EHAADIQMVNFDYHQMVKGGKAEKLHSVLKPQVQKFLDYG-FFYFNGSE-VQRCQSGTVRTNCLDCLDRTNSVQAFLGLEMLAKQLEALGLAEKPQLVTR--FQEVFRSMWSVNGDSISKIYAGTGALEGKAK---LKDGARSVTRTIQNNFFDSSKQEAIDVLLLGNTLNSDLADKARALLTTGSLRVSEQTLQSASSKVLKSMCENFYKYSKPKKIRVCVGTWNVNGGKQFRSIAFKNQTLTDWLLDAPKLAGIQEFQDKRSKPTDIFAIGFEEMVELNAGNIVSASTTNQKLWAVELQKTISR---DNKYVLLASEQLVGVCLFVFIRPQHAPFIRDVAVDTVKTGMGGATGNKGAVAIRMLFHTTSLCFVCSHFAAGQSQVKERNEDFIEIARKLSFPMGRMLFSHDYVFWCGDFNYRIDLPNEEVKELIRQQN---WDSLIAGDQLINQKNAGQVFRGFLEGKVTFAPTYKYDLFSDDYDTSEKCRTPAWTDRVLWRRRKWPFDRSAEDLDLLNASFQDESKILYTWTPGTLLHYGRAELKTSDHRPVVALIDIDIFEVEAEERQNIYKEVIAVQGPPDGTVLVSIKSSLPENNFFDDALIDELLQQFASFGEVILIRFVEDKMWVTFLEGSSALNVLSLNGKELLNRTITIALKSPDWIKNLEEEMSLEKISIALPSSTSSTLLGEDAEVAADFDMEGDVDDYSAEVEELLPQHLQPSSSSGLGTSPSSSPRTSPCQSPTISEGPVPSLPIRPSRAPSRTPGPPSA-----------QSSPIDAQPATPLPQKDPAQPLEPKRPPPPRPVAPPTRPAPPQRPPPPSGARSPAPTRKEFGGIGAPPSPGVARREMEAPKSPGTTRKDNIGRSQPS------------PQAGLAG-------PGPAGYSTARPTIPPRAGVISAPQSHARASAGRLTPESQSKTSETSKGS-TFLPEPLKPQAAFPPQSSLPPPAQRLQEPLVP--------------VAAP-MPQSGPQPNLETP---------PQPPPRSRSSHSLPSEASSQPQ--------VKTNGISDGKRESPLKIDPFEDLS----FNLLAVSKAQLSVQTSPVPTPDPKR-LIQLPSATQS--NVLSSVSCMPTMPPIPARSQSQENMRSSPNPFITGLTRTNPFSDRTAAPGNPFRAKSEESEATSWFSKEEPVTISPFPSLQPLGHNKSRASSSLDGFKDSFDLQGQSTLKISNPKGWVTFEEEEDFGVK--GKSKSACSDLLGNQPSSFSGSNLTLNDDWNKGTNVSFCVLPSRRPPPP--PVPLLPPGTSPPVDPFTTLASKASPTLDFTER", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M2B1N6-1", "uniprot_id": "A0A8M2B1N6_DANRE", "id": "A0A8M2B1N6-1", "name": "Synaptojanin-1", "aln": "--MAFSKGYRIYHKLDPPPYSVIVETR------NREECLMFESGAVAVLSAAEKETIKASYTKMLDAYGILGVLRLNLGDSMLHSLVVVTGCSS---------VGKVQDSEVFRVTGTDFVSLKN--------------------------------------------------DPTDEDRIADVRKVLNSGNFYFAWSSTG--VSLDLSLNAHRRIREDTSDNRFFWNQSLHLHLKHYG----------VNCDDWLLRLMCGGVEIRTIYAGHKQAKACVISRLSSERAGTRFNVRGTNDDGQVANFVETEQIIFLDDKVSSFIQIRGSIPLFWE-QPGIQVGSHRVKLSRGFEANAPAFERHFSALKRLYGKQLIINLLGMKEGEHMLSKAFQSHLKAS---EHSNAVKMLNFDYHQMVKGGKTEKLQTVLKPQISKFVEDCDFFYYSGETGIQRCQSGTIRSNCLDCLDRTNSVQAFIALEMLPKQLEAMGLTEKPQLVAR--FQEVFRSMWSTNGDSISKIYAGTGALDGKAKGGKLKDGARSVTRTIQNNFFDSSKQEAIDILRLGSTLNSDLADKARALLTTSSLYVSEPILQSASPRVLLGMCQNHFKYTRPKKIRVCVGTWNVNGGKQFRSIAFRNHTLNDWLLDAPKKAGHPEFQDVKNNPVDIFAIGFEEMVELNAGNIVSASTTNQKLWAAELQKNISR---DQRYVLLASEQLVGVCLFVFIRPQHAPFIRDVAVDTVKTGMGGATGNKGGVAIRMLFHTTSICFVCSHFAAGQSQVKERNDDYNEIARKLSFPMGRLLYSHDYVFWCGDFNYRINIPNEEVKELIRQQN---WDALIGGDQLVEQKNAGQVFRGFIEGKLDFAPTYKYDLFSEDYDTSEKCRTPAWTDRVLWKRRKWNFDKTAEELELNVVGAPVNEEEQYPWSPGDLKYYGRAELKTSDHRPVVAIIDVDILEVDPEARHQVYKEVIALQGPPDGTILVSLCSSGPDD-YFDDALIDDLLDKFANFGEVILIRFVEEKMWVTFLEGYSALAALSLSGSTVNGKTIDIRLRSPGWIKSLEEEMSVERICGSIPTSTSSTLLAENSDLGEEYDMEGDVD---EEVEDILPQHLQPGAGMDLSASPATSPRTSPCPSPTHG---EPAPPIRPSRAPPRTAGPPQGGLSPASIRRELAGSPVDGQPAG----APFSQGLEPKRPPPPRPNAPPARPAPPQRPPPPSGGRSPTPVRKDSAGFAEPLNLEFDLTDNEGQKSPALARADAAGRGQATGPAPGGIPRPIPPRAGVISVTPQARPPPPAHPGAPRPTAEVHPGAP-RPSPDNHPGAPRPTAEPQSKPSELPLGPPPTLPGPVRPQMTSPMQPQSVSPVQPPVQPQLPPPIQSQLPPPMQPTLPAPLMPQQAPQTSAGAAAAPQPGLASPKPPPRSRSSHALPPESAPAPT--------TQAKNMNGVQREAQWNLDPFDMLNPQSLFQNTPFTASLPRSSSSSTSTPSPSSSSSTLPSNLSLFSAPDTSSASCLLAPPAPSRSKSQETLRCSPNPFLTDIQPR-PNSTNPFTSGLQFSPRRS---LTPDFYTQMQASKPDFNRAMSAVGHSSTLPPTFS--RQQSLVTATAPAPNKQTQKWVTFDDDLDFLSKRVGTGPLASPLPFPQTQSSFP--------SSGFGMDNNWASLPTSAFPAIPPPVPTR----TNTSIKNAQLPSRN----DFTER", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P40559-1", "uniprot_id": "INP51_YEAST", "id": "P40559-1", "name": "Phosphatidylinositol 4,5-bisphosphate 5-phosphatase INP51", "aln": "-MRLFIGRRSRSIVISSNNYCLSFQRLRSIPGASSQQRQLSKTPSVTIKSYPDTDLSSDSNYLEVKSCIFNGLLGLVCLNGDIYVAVISGVQNVGFPRWKLIDHQVRPSESIYKVLDVDFYSLENDVFDYLLCERS----------------------------------EQNYDKLIHEHPCGPLKKLFSDGTFYYSRDFDISNIVKNHGLSHNLEYTVDNQDLSFIWNANLASEVINWRSKISNEEKQLFANAGFLTFVIRGYCKTALIEDGPNTASITIISRISTESKQDTLELEGISEDGRVSLFVETEIVVTTEKFIFSYTQVNGSIPLFWESVESQLLYGKKIKVTKDSIEAQGAFDRHFDNLTSKYGVVSIVNIIKPKSESQEKLALTYKDCAES------KGIKITNIEYSSSVLT---KSPHKLLYLLKQDIYEFGAFAYDISRGIYFAKQTGVLRISAFDSIEKPNTVERLVSKEVLELTTNEIDVFELTSPFLD-----AHDKLWSENYYWLDRTYTKHTKNSGKYT-----------------------------------------------KVYSKLFGSRVRLYDPLHIYISQYLKQLRSKYTFEKDISIFAGTFNISGKIP-------KDDIKDWIFPKSMS--------KEDEMADLYVIGLEEVVELTPGHMLATDPYVRQFWEKKILTLLNGPGRKKKYIRLWSTQLGGILLLLFMNETEYSKVKHIEGDVKKTGFGGMASNKGAVAVSFKYSATRFCVLVSHLAAGLENVEQRHNDYKTIAKSIRFSKGLRIKDHDAIIWMGDFNYRILMSNEDVRRKIVSKE---YASLFEKDQLNQQMIAGESFPYFHEMAIDFPPTYKFDPGTKNYDTSEKMRIPAWTDRILSRGE----------------------------VLEQLEYKCCEDILFSDHRPVYAIFRARVTVVDEQKKTTLGTQIYEKIMER---------------------------------------------------------------------------------LEGLDDDEKIAVLSDDAFVIES---------------------------------FEGSDSIAGPTHSPTPIPEPKRGRK-----LPPPSSDLKKWWIGSG------------------------------------------KQVKVVLDVDPAVYMINPKRDPNPFVENEDEPLFIER--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . : . . : .. : . . . . . : : *.: * : :. .: . : :: .:* .*. . :. ::*::..*.**:: . : . . : ::** * .: : . .:* :: * : . :**: * : :: .* .::..*: ***** :: .. :: *:.**:*:*** : ::::::. .*:.*: ** ::*:: *. . .. * : : .::: . :: . : . : * * * .* ..:*.:::.* : :. : : : : . . . :*: : :.: *: ... . : :. : : . *:: ..* : *::*:.* . :..*:: . *: .:*::*::**..* :: :. .:* : :. ..:*: * *: .: ::.* . . ::.: . ***: * :.***.*:: : : :* :*.: :*::** ::.:*..*: * : : *. : ** ::* **:**** :.*::*:. : :: *: *** * * * * : * ****:* : **:*** * *:****:: : . : ***:** * : *: : : : .: : . . : . * . *. . * . : ", "identical_positions": 125, "similar_positions": 268, "identity": "7.17%" }, { "cls_id": "homologset.agr.MGI:1354962", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O35142-1", "uniprot_id": "COPB2_RAT", "id": "O35142-1", "name": "Coatomer subunit beta'", "aln": "MPLRLDIKRKLTAMSDRVKSVDLHPTEPWMLASLYNGSVCVWNHETQTLVKTFEVCDLPVRAAKFVARKNWVVTGADDMQIRVFNYNTLERVHMFEAHSDYIRCIAVHPTQPFILTSSDDMLIKLWDWDKKWSCSQVFEGHTHYVMQIVINPKDNNQFASASLDRTIKVWQLGSSSPNFTLEG-HEKGVNCIDYYSGGDKPYLISGADDRLVKIWDYQNKTCVQTPEGHAQNVSCATFHPELPIIITGSEDGTVRIWHSSTYRLESTLNYGMERVWCVASLRG--SNNVALGYDEGSIIVKLGREEPAMSMDANG-KIIWA--KHSEVQQANLKAMGD-TEIKDGERLPLAVKDMGSCEIYPQTIQHNPNGRFVVVCGDGEYIIYTAMALRNKSFGSAQEFAWAHDSSEYAIRESNSVVKIFKNFKEKKSFKPDFG--AESIYGGFLLGVRSVNGLAFYDWENTELIRRIEIQPKHIFWSDSGELVCIAT------EESFFILKYLSEKVLAAQETHEGVTEDGIEDAFEVLGEIQEIVKTGLWVGDCFIYTSSVNRLNYYVGGEIVTIAHLDRTMYLLGYIPKDNRLYLGDKELNIVSYSLLVSVLEYQTAVMRRDFSMADK-VLPTIP-KEQRTRVAHFLEKQGFKQQALTVSTDPEHRFELALQLGELKIAYQLAVEAESEQKWKQLAELAISKCQFSLAQECLHHAQDYGGLLLLATASGNASMVNKLAEGAERDGKNNVAFMSYFLQGKLDACLELLIRTGRLPEAAFLARTYLP--SQVSRVVKLWRENLSKVNQKAAESLADPTEYENLFPGLKEAFVVEEWVKETHADLWPAKQYPLVTPNEERNVMEEAKRFQPSRATAQQEPDGKPAS-SPVIMASQTTHKEEKSFQ----ELEDDLDTMELED-IDTTDINLDEDILDD-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O55029-1", "uniprot_id": "COPB2_MOUSE", "id": "O55029-1", "name": "Coatomer subunit beta'", "aln": "MPLRLDIKRKLTARSDRVKSVDLHPTEPWMLASLYNGSVCVWNHETQTLVKTFEVCDLPVRAAKFVARKNWVVTGADDMQIRVFNYNTLERVHMFEAHSDYIRCIAVHPTQPFILTSSDDMLIKLWDWDKKWSCSQVFEGHTHYVMQIVINPKDNNQFASASLDRTIKVWQLGSSSPNFTLEG-HEKGVNCIDYYSGGDKPYLISGADDRLVKIWDYQNKTCVQTLEGHAQNVSCASFHPELPIIITGSEDGTVRIWHSSTYRLESTLNYGMERVWCVASLRG--SNNVALGYDEGSIIVKLGREEPAMSMDANG-KIIWA--KHSEVQQANLKAMGD-TEIKDGERLPLAVKDMGSCEIYPQTIQHNPNGRFVVVCGDGEYIIYTAMALRNKSFGSAQEFAWAHDSSEYAIRESNSIVKIFKNFKEKKSFKPDFG--AESIYGGFLLGVRSVNGLAFYDWENTELIRRIEIQPKHIFWSDSGELVCIAT------EESFFILKYLSEKVLAAQETHEGVTEDGIEDAFEVLGEIQEIVKTGLWVGDCFIYTSSVNRLNYYVGGEIVTIAHLDRTMYLLGYIPKDNRLYLGDKELNIVSYSLLVSVLEYQTAVMRRDFSMADK-VLPTIP-KEQRTRVAHFLEKQGFKQQALTVSTDPEHRFELALQLGELKIAYQLAVEAESEQKWKQLAELAISKCQFSLAQECLHHAQDYGGLLLLATASGNASMVNKLAEGAERDGKNNVAFMSYFLQGKLDACLELLIRTGRLPEAAFLARTYLP--SQVSRVVKLWRENLSKVNQKAAESLADPTEYENLFPGLKEAFVVEEWVKETHADLWPAKQYPLVTPNEERNVMEEAKGFQPSRPTAQQEPDGKPAS-SPVIMASQTTHKEEKSLL----ELEVDLDNLELED-IDTTDINLDEDILDD-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P35606-1", "uniprot_id": "COPB2_HUMAN", "id": "P35606-1", "name": "Coatomer subunit beta'", "aln": "MPLRLDIKRKLTARSDRVKSVDLHPTEPWMLASLYNGSVCVWNHETQTLVKTFEVCDLPVRAAKFVARKNWVVTGADDMQIRVFNYNTLERVHMFEAHSDYIRCIAVHPTQPFILTSSDDMLIKLWDWDKKWSCSQVFEGHTHYVMQIVINPKDNNQFASASLDRTIKVWQLGSSSPNFTLEG-HEKGVNCIDYYSGGDKPYLISGADDRLVKIWDYQNKTCVQTLEGHAQNVSCASFHPELPIIITGSEDGTVRIWHSSTYRLESTLNYGMERVWCVASLRG--SNNVALGYDEGSIIVKLGREEPAMSMDANG-KIIWA--KHSEVQQANLKAMGD-AEIKDGERLPLAVKDMGSCEIYPQTIQHNPNGRFVVVCGDGEYIIYTAMALRNKSFGSAQEFAWAHDSSEYAIRESNSIVKIFKNFKEKKSFKPDFG--AESIYGGFLLGVRSVNGLAFYDWDNTELIRRIEIQPKHIFWSDSGELVCIAT------EESFFILKYLSEKVLAAQETHEGVTEDGIEDAFEVLGEIQEIVKTGLWVGDCFIYTSSVNRLNYYVGGEIVTIAHLDRTMYLLGYIPKDNRLYLGDKELNIISYSLLVSVLEYQTAVMRRDFSMADK-VLPTIP-KEQRTRVAHFLEKQGFKQQALTVSTDPEHRFELALQLGELKIAYQLAVEAESEQKWKQLAELAISKCQFGLAQECLHHAQDYGGLLLLATASGNANMVNKLAEGAERDGKNNVAFMSYFLQGKVDACLELLIRTGRLPEAAFLARTYLP--SQVSRVVKLWRENLSKVNQKAAESLADPTEYENLFPGLKEAFVVEEWVKETHADLWPAKQYPLVTPNEERNVMEEGKDFQPSRSTAQQELDGKPASPTPVIVASHTANKEEKSLL----ELEVDLDNLELED-IDTTDINLDEDILDD-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "O62621-1", "uniprot_id": "COPB2_DROME", "id": "O62621-1", "name": "Coatomer subunit beta'", "aln": "MPLKLDIKRRLTSRSDRVKCVDLHPAEPWMLCALYNGHVHIMNYENQQMVKDFEVCDVPVRSARFVARKNWILTGSDDMQIRVFNYNTLEKVHSFEAHSDYLRCIAVHPTQPLVLTSSDDMLIKLWNWEKMWACQRVFEGHTHYVMQIVFNPKDNNTFASASLDRTVKVWQLGSNFANFTLEG-HEKGVNCVDYYHGGDKPYLISGADDRLVKIWDYQNKTCVQTLEGHAQNISAVCFHPELPIVLTGSEDGTVRIWHSGTYRLETCLNYGFERVWTISSMRG--TNNVALGYDEGSIIIKVGREEPAMSMDVVGSKIIWA--KHSEMQQVNLKTIADGTEIKDGERLPVATKDMGACEIYPQTIAHNPNGRFVVVCGDGEYIIYTSMALRNKAFGSAQEFVWALESNEYAIRENNGTVRLFRNFKERKSFTPEYG--AESIYGGYYFGVKTSSGLAFYDWETLQLVRRIEVQPKNVFWNESGSLVCLAT------DDSYFVLGVDTAQVANAVETKEGLEDDGVESAFNVLGEVSECVKTGLWVGDCFIYTNSVNRINYYVGGEIVTVSHLDRTMYLLGYVPKDNRIYLGDKELNVISFCLQLSVLEYQTAVMRRDFERADV-VLPTIP-KEHRTRVAHFLEKQGFKSQALQVSTDADHKFDLALQIGDLEIALKLARESENSQKWSQLADVASSKNNMSLVKECMQKANDLSGLLLLSTASGDAQLLEVVGAAGSAQGHHNLAFLSAFLRSDVERCLEILIETNRLPEAAFFARTYLP--SQMSRIVELWREKLGKVNEKAGQSLADPAQYTNLFPGLGDALRVEQHLQEERARKAPARLAANLPLNSERHPLQELFAAEQGAAGQHLEEKVKPAYVPAQAVVSSSQVAEPTSAADDDDDLDLEIDGITLDDNIDTTDVNLDDDFLSDD", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P41811-1", "uniprot_id": "COPB2_YEAST", "id": "P41811-1", "name": "Coatomer subunit beta'", "aln": "--MKLDIKKTFSNRSDRVKGIDFHPTEPWVLTTLYSGRVELWNYETQVEVRSIQVTETPVRAGKFIARKNWIIVGSDDFRIRVFNYNTGEKVVDFEAHPDYIRSIAVHPTKPYVLSGSDDLTVKLWNWENNWALEQTFEGHEHFVMCVAFNPKDPSTFASGCLDRTVKVWSLGQSTPNFTLTTGQERGVNYVDYYPLPDKPYMITASDDLTIKIWDYQTKSCVATLEGHMSNVSFAVFHPTLPIIISGSEDGTLKIWNSSTYKVEKTLNVGLERSWCIATHPTGRKNYIASGFDNGFTVLSLGNDEPTLSLDPVG-KLVWSGGKNAAASDIFTAVIRGNEEVEQDEPLSLQTKELGSVDVFPQSLAHSPNGRFVTVVGDGEYVIYTALAWRNKAFGKCQDFVWGPDSNSYALIDETGQIKYYKNFKEVTSWSVPMHSAIDRLFSGALLGVKSDGFVYFFDWDNGTLVRRIDVNAKDVIWSDNGELVMIVNTNSNGDEASGYTLLFNKDAYLEAANNGNIDDSEGVDEAFDVLYELSESITSGKWVGDVFIFTTATNRLNYFVGGKTYNLAHYTKEMYLLGYLARDNKVYLADREVHVYGYEISLEVLEFQTLTLRGEIEEAIENVLPNVEGKDSLTKIARFLEGQEYYEEALNISPDQDQKFELALKVGQLTLARDLLTDESAEMKWRALGDASLQRFNFKLAVEAFTNAHDLESLFLLHSSFNNKEGLVTLAKDAERAGKFNLAFNAYWIAGDIQGAKDLLIKSQRFSEAAFLGSTYGLGDDAVNDIVTKWKENLILNGKNTVSERVCGAEGLPGSSSSGDAQPLIDLDSTPAPEQADENKEAEVEDSEFKESNSEAVEAEKKEEEAPQQQQSEQQPEQGEAVPEP---VEEES------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ::****: :: ***** :*:**:***:* :**.* * : *:*.* *: ::* : ***:.:*:*****::.*:**::******** *:* ****.**:*.******:* :*:.***: :***:*:: *: .:.**** *:** :.:**** . ***..****:***.**.. .**** :*:*** :*** ****:*:.:** :******.*:** * *** .*:* . *** ***:::******::**:*.**::*. ** *:** * ::: .* :* *:*:* ::.:*.:**::*:* * *::*: *:: .: .: . *:::.* *.: .*::*: :::**:: *.******.* *****:***::* ***:**..*:*.*. :*..**: :... :: ::**** .*:. : ::.* :**:: . : *:**:. *:***:::.*.::*.:.*.** :.. : * : * . * :. : .:*::.**:** *:.* :.:* **** **:*.:.**:**:***: .::* : ******:.:**::**.*:*::: .: : :.***:** .:* ::. * ***.: *: *::*:*** * : .:** :*.* :::*:***::*:* :* .* : . . ** *.: : .: :: *. *.: :*:* .*:** :: .: . : :. .. *: *:** : :: ..:: . ::**.: *:.****:. ** . :. :* *:*:* .::: .. . :: .. :* : : . . . . : .. :. .* : : . : : . * * ", "identical_positions": 317, "similar_positions": 325, "identity": "34.05%" }, { "cls_id": "homologset.agr.MGI:1354963", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9QZL9-1", "uniprot_id": "DKKL1_MOUSE", "id": "Q9QZL9-1", "name": "Dickkopf-like protein 1", "aln": "----------MCRLRVLLLLLPLAFVSSSALPIHDVDSQQNTSGFLGLQRLLQSFSRLFLKNDLLRDLDNFFSSPMDFRDLPRNFHQEENQEHRMGNHTLSSHLQIDKVTDNQTGEVLISEKVEASIEPER-NPEGDWKVPKVEAKEPPVPVQKVTDSLHPEPR-QVAFWIMKMPRRRTQPDVQDGGRWLIEKRHRMQAIRDGLRGGAREDSLEDGVHIPQHAKLPVRKTHFLYILRPSQQL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0ABK0L829-1", "uniprot_id": "A0ABK0L829_RAT", "id": "A0ABK0L829-1", "name": "", "aln": "----------MGRLGVLLLLLPLAFVCASAVPIHDADSQQNSSGFLGLQSLLQSFSRLFLKNDLLQDLDNFFSSPMDFRDLPRNFHQEQNQEHRMGNHTLSSHLQIDKMTDNQTGEVLISEKVVASIEPEV-NPEGDWKVPKVEAKEALVPVQKATDSLHPEPR-RVAFWIMKMPRRRTQPDVQDGNRWLTEKRHRMQAIPAAIRWGP---------------CIPACPTPYPNTIWK----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9UK85-1", "uniprot_id": "DKKL1_HUMAN", "id": "Q9UK85-1", "name": "Dickkopf-like protein 1", "aln": "MGEASPPAPARRHLLVLLLLLSTLVIPSAAAPIHDADAQESSLGLTGLQSLLQGFSRLFLKGNLLRGIDSLFSAPMDFRGLPGNYHKEENQEHQLGNNTLSSHLQIDKMTDNKTGEVLISENVVASIQPAEGSFEGDLKVPRMEEKEALVPIQKATDSFHTELHPRVAFWIIKLPRRRSHQDALEGGHWLSEKRHRLQAIRDGLRKGTHKDVLEEGTESSSHSRLSPRKTHLLYILRPSRQL", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :* ******. .: ::* ****.*:*:.: *: *** ***.*******.:**:.:*.:**:*****.** *:*:*:****::**:**********:***:********:* ***:* . *** ***::* **. **:**.***:*.* : :*****:*:****:: *. :*.:** *****:*** .:* *. :. * : ", "identical_positions": 118, "similar_positions": 57, "identity": "48.76%" }, { "cls_id": "homologset.agr.MGI:1355075", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A0G2KAS0-1", "uniprot_id": "A0A0G2KAS0_RAT", "id": "A0A0G2KAS0-1", "name": "Calpain-15", "aln": "-----------------------------------------MGSSASSLAAETESDHGFPGGPPYPGPPTAAGWCRSGPGETVWGSALVTRQH------PRPRA----------------RSHTHSPGSMATVG---EWSCARCTFLNPAGQRQCSICEAP---------------------------------RHKPDLDQILRLS-VEEQKWPCARCTFRNFLGKEACEVCGFTPEPVPGAPLL---------------------------------------PIINGVLPKPPTILV-------------------EPKGNSKEETGPVRTAGLVATEPARGHPEKEEE--------EKEQEDDGERADPGSGWACQRCTLHNTPVASSCSACGGPRKLSLPRIPPEALVVPEVVAPTG-FHVVPPPS------------------------------------------------QPALPGEGAEAESPSTSQGPTSTDQEPPRVPLFSPFSPTLQNNPVPRSRREVPPQLQPPVPEGAQSSASTSS-------KGPQQGPGRAAAGASRLAELLSGKELLPGKRLSV-----------------LEEEAPESSPARCES--------CSDVIDLAGDVVR---------------------------------------------------YTPASPSSPDFTTWSCARCTLRNPTTASRCSVCGGSKLHGFQEHSEP------PTHCPDCGADKPG--PCVGSCGRA-----PSAHKAARLLPD------------------------------------------------------------------------------------------------------------------------------------------RPGQWACPACTLINTPRAKHCAACHTPQLLVTQCRGATPLR------------RRESMHVEKRRQTDEGEAKALWENIVAFCRENSVNFVDDSFPPGPASVGFPVGDSVQQR--VKQWLRPHEINCSVFRDHGTPWSVFHTLRPSDILQGLLGNCWFLSALAVLAERPDLVERVMVTRSLCAEGAYQVRLCKDGTWTTVLVDDMLPCDEAGFLLFSQAQRKQLWVALIEKALAKLHGSYFALQAGRAIEGLATLTGAPCESLALQVSST-NPREEPVDTDLIWAKMLSSKEAGFLMGASCGGGNMKVDDAAYESLGLRPRHAYSVLDVRDVQGSRLLRLRNPWGRFSWNGSWSDEWPHWPGHLRAELMPHGSSEGVFWMEYSDFIRYFDSVDICKVHSDWQEARVQGCFPSTASGPVGVTALTVLERASLEFALFQEGSRRSDSVDSHLLDLCILVFRATFGTGGRLSLGRLLAHSKRAVKKFVNCDVMLEPGEYAVVCCAFNHWNPAPPGPPAQGKGPSQMRPTPAFPSSEPQSPPAGKLLAPLSTPPTASSPSAGVPRGAPEPPGHVLAVYSSRLVMVEPVEAQPTTLADAIILLTESRGERHEGREGMTCYYLTHGWAGLIVVVENRHPKSYLHVQCDCTDSFNVVSTRGSLRTQDSVPPLHRQVLVILSQLEGNAGFSITHRLAHRKAAQAFLSDWTASRGTHSPPLTPDVAGLHGPRPL-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9JLG8-1", "uniprot_id": "CAN15_MOUSE", "id": "Q9JLG8-1", "name": "Calpain-15", "aln": "---------------------------------------------------------------------------------------------------------------------------------MATVG---EWSCARCTFLNPAGQRQCSICEAP---------------------------------RHKPDLDQILRLS-VEEQKWPCARCTFRNFLGKEACEVCGFTPEPVPGAPLL---------------------------------------PIINGVLPKPPTILV-------------------EPKGSGKEEAGPVRTAGLVATEPARGRPEGEEEREERGEEEEKEQEGEGERAEPGSGWACQRCTLHNTPVASSCSACGGPRKLSLPRIPPEALVVPEVVAPTG-FHVVPAPS------------------------------------------------QPVLPGEGAEADSPSTSQGPTSTDQEPPRVPLFSPFSPTLQNNPVPRSRREVPPQLQPPVPEAVQSSASTSS-------KGPQQGPGRAAAGASRLAELLSGKELLPGKRLSV-----------------LEEEVPESSPARCES--------CSDVIDLAGDIVR---------------------------------------------------YTPASPSSPDFTTWSCARCTLRNPTTAPRCSVCGGSKLHGFQEHSEP------PTHCPDCGANKPG--PCVGSCGRA-----PSAHKAVRLLPD------------------------------------------------------------------------------------------------------------------------------------------RPGQWACPACTLINTPRAKHCAACHTPQLLVTQCRGATPLR------------RRESMHVEKRRQTDEGEAKALWENIVAFCRENSVNFVDDSFPPGPASVGFPVGDSVQQR--VKQWLRPHEINCSVFRDHGTPWSVFHTLRPSDILQGLLGNCWFLSALAVLAERPDLVERVMVTRSLCAEGAYQVRLCKDGTWTTVLVDDMLPCDEAGFLLFSQAQRKQLWVALIEKALAKLHGSYFALQAGRAIEGLATLTGAPCESLALQVSST-NPREEPVDTDLIWAKMLSSKEAGFLMGASCGGGNMKVDDAAYESLGLRPRHAYSVLDVRDVQGSRLLRLRNPWGRFSWNGSWSDEWPHWPGHLRAELMPHGSSEGVFWMEYSDFIRYFDSVDICKVHSDWQEARVQGCFPSTAGGPVGVTALTVLERASLEFALFQEGSRRSDSVDSHLLDLCILVFRATFGTGGRLSLGRLLAHSKRAVKKFVNCDVMLEPGEYAVVCCAFNHWNPAPPGPPAQ-----------------------------------ASSPSAGVPRGAPEPPGHVLAVYSSRLVMVEPVEAQPTTLADAIILLTESRGERHEGREGMTCYYLTHGWAGLIVVVENRHPKSYLHVQCDCTDSFNVVSTRGSLRTQDSVPPLHRQVLVILSQLEGNAGFSITHRLAHRKAAQAFLSDWTASRGTHSPPLTPDVAGLHGPRPL-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O75808-1", "uniprot_id": "CAN15_HUMAN", "id": "O75808-1", "name": "Calpain-15", "aln": "---------------------------------------------------------------------------------------------------------------------------------MATVG---EWSCVRCTFLNPAGQRQCSICEAP---------------------------------RHKPDLNHILRLS-VEEQKWPCARCTFRNFLGKEACEVCGFTPEPAPGAAFL---------------------------------------PVLNGVLPKPPAILG-------------------EPKGSCQEEAGPVRTAGLVATEPARGQCEDKDE------EEKEEQEEEEGAAEPRGGWACPRCTLHNTPVASSCSVCGGPRRLSLPRIPPEALVVPEVVAPAG-FHVVPAAP------------------------------------------------PPGLPGEGAEANPPATSQGP-AAEPEPPRVPPFSPFSSTLQNNPVPRSRREVPPQLQPPVPEAAQPSPSAGC-------RGAPQGSG--WAGASRLAELLSG------KRLSV-----------------LEEEATEGGTSRVEAGSST---SGSDIIDLAGDTVR---------------------------------------------------YTPASPSSPDFTTWSCAKCTLRNPTVAPRCSACGCSKLHGFQEHGEP------PTHCPDCGADKPS--PCGRSCGRV-----SSAQKAARVLPE------------------------------------------------------------------------------------------------------------------------------------------RPGQWACPACTLLNALRAKHCAACHTPQLLVAQRRGAAPLR------------RRESMHVEQRRQTDEGEAKALWENIVAFCRENNVSFVDDSFPPGPESVGFPAGDSVQQR--VRQWLRPQEINCSVFRDHRATWSVFHTLRPSDILQGLLGNCWFLSALAVLAERPDLVERVMVTRSLCAEGAYQVRLCKDGTWTTVLVDDMLPCDEAGCLLFSQAQRKQLWVALIEKALAKLHGSYFALQAGRAIEGLATLTGAPCESLALQLSST-NPREEPVDTDLIWAKMLSSKEAGFLMGASCGGGNMKVDDSAYESLGLRPRHAYSILDVRDVQGTRLLRLRNPWGRFSWNGSWSDEWPHWPGHLRGELMPHGSSEGVFWMEYGDFVRYFDSVDICKVHSDWQEARVQGCFPSSASAPVGVTALTVLERASLEFALFQEGSRRSDAVDSHLLDLCILVFRATFGSGGHLSLGRLLAHSKRAVKKFVSCDVMLEPGEYAVVCCAFNHWGPPLPGTPAP----------------------------------QASSPSAGVPRASPEPPGHVLAVYSSRLVMVEPVEAQPTTLADAIILLTESRGERHEGREGMTCYYLTHGWAGLIVVVENRHPKAYLHVQCDCTDSFNVVSTRGSLRTQDSVPPLHRQVLVILSQLEGNAGFSITHRLAHRKAAQAFLSDWTASKGTHSPPLTPEVAGLHGPRPL-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M2BLF5-1", "uniprot_id": "A0A8M2BLF5_DANRE", "id": "A0A8M2BLF5-1", "name": "", "aln": "-----------------------------------------MGSSASSLTTDRESDHGFGTAPFPAAAP--MGWLRTSHSSPVWGTTFITRQQQQHQQPIPHRE----------------RSHSHSPGSMEAVVRNSDWSCGRCTFLNSSGSMRCSICEAP---------------------------------RQKPDLNHILRLSSAEEPRWSCPRCTLTNHHGLGSCSVCGAAPV-TPNGPLP---------------------------------------PKQ--TPPTPIDLAS-------------------SPEPKGQVANGESQCIESNGEVPMSGQGS--------------------------SEWACPRCTLVNTPVALSCSACGGPRKLSLPKIPPEALVVPEVRTPVAGFPTQTAGA------------------------------------------------SAPLLIDLTEDSPP---QAP-SETPSPPPVPFLPPSLSSLQNNPVPRSRREVPPPGRPPNPGPSPTSPSSCPP------TKPKPLPPSGNYPVKRLSVLEEEEPNNPTPPVTSPPSWKCPGCS-------APTAPPSSSAGRCDACRGSRPGSGGDVIDVLGESVR---------------------------------------------------FTPASPSSPDFSSWACSKCTLRNPTGAGHCTACGSSKLHGFSE----------PSSCSSCSRKQPHSHPRAFTSTSS-----SSSISSPSAQDK------------------------------------------------------------------------------------------------------------------------------------------SVCQWTCPACTLLNEGRMKHCAACHTPQQYLNLRKTGKPLK------------RRESMHVEARRRTDEGEAKELWENIVSFCRENAVNFVDDSFPPGPRSVGFPENDSVQQR--IKKWLRPHEINCNNFKDRGVKWSVFRTPRPSDILQGLLGNCWFLSALAVLAERPELVERVMITRSICQEGAYQVRLCKDGMWTTVLVDDMLPCDEYGFLLFSQAQRRQLWVALIEKALAKLHGSYFALQAGRAIEGLATLTGAPCESLMLQVSST-NPREEPIDTDLIWAKMLSSKEAGFLMGASCGGGNMKVDDAVYESLGLRPRHAYSILDVRDVQGYRLLRLRNPWGRFSWNGSWSDEWSDWPQHLRHELMAHGSSEGVFWMEYGDFIKYFDSVDICKIHPDWQEVRLQGCFPCRASKPVTVTALTVLERTALEFALFQEGSRRSDTADSHLLDLCIMVFRASFSNGNKLVLGRLLAHSKRAVKKFVGCDVMLEPGEYAVVCCAFNHWQMDLSGASTP-----------------------------------VSSPTN-ARRPSQDFPGYILAIYSSRQVMVEQVEATSTTLADAIILLTENKGERHEGREGMTCYYLTHGWAGLIVVVENRHPKYYLHVSCDCTDSFNVVSTRGSLKTIDSVPPLHRQVLVVLSQLEGNAGFSITHRLAHRKAAQASLGDWTSSKATHSPQLTPDTDGLHRPRPL-", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P27398-1", "uniprot_id": "CAND_DROME", "id": "P27398-1", "name": "Calpain-D", "aln": "MGTISSVLQWSCTKCNTINPTESLKCFNCGTVRKVFPQQQQQQHRSSSITASWTADDALEQEQAEKGQERDKEKGRAAVARSEYKHVYKSLLRGCLKRPQRNSQNLPANCVDCEDTRKYIKSSIELYRHFSNPALNRRWVCHACGTDNSSVTWHCLICDTVSYLAPIYKDAIAADRGQDLAGSLGNRGELLAADHSHPHHHHHYLHQELEEQHQHQLHSQHLHKRHLKGRSASGSGSGPGSGSGLRRTQSLSTAIDKSASGRSCHICYANNQSKDIFNLPQIKPAPQLTGIPPVAACSNSRFAIANDTFCRRKQNNNNKNQNHKVVRESGAKRKYNFTITTLSRSAAKDAGHG-QMKPLRQVVNLNLNLQQEPQQKSPANPQQLQRKTQREPAAVSMNPTQFTIPRNG-VFIAVNEWSEPMASSSSVSSSSNHHHHHHSNSNSNSSGNSNIINNNSSSSSGSNKLYENECVALAQQQLRAAAAQAAQAAATAVAIASSPSAKAMAEPAPTATMPIYAQVNKQHKLKKKQQIASESQTNNNTGSGEIADAVSESLTAGLGTSTDGSGEASESESQVEEHSIYAKVWKGPRKATESKIMHDPGSSSRLSGAASAAAGTASAGAIAAAVGAAAASRHDNKTQLGNGSRSKMWICIKCSYAYNRLWLQTCEMCEAKAEQQQQQLQLQQQQQQQQQHHHHHLQQQQAEAPRDEPWTCKKCTLVNYSTAMACVVCGGSKLKSISSIEDMTLRKGEFWTCSHCTLKNSLHSPVCSACKSHRQPQLSMAMEAVRERPDGQSYEEQDAAAVGGGGGSAHQSGANEVKAPTALNLPLTSVALPMPMLQLPTSTAAGLRGSRSPSPRMQLLPSLQQQRNSSSSGAIPKRHSTGGSIVPRNISIAGLANYNLQQGQGVGSASVVSASGAGSGAGAVGASTSTKKWQCPACTYDNCAASVVCDICSSPRGLASAVLGEALGRKSVRVALTPADIRQESKLMENLRQLEETEALTKWQNIIQYCRDNSELFVDDSFPPAPKSLYYNPASGAGEGNPVVQWRRPHEINCDGG--AYPPWAVFRTPLPSDICQGVLGNCWLLSALAVLAEREDLVKEVLVTKEICGQGAYQVRLCKDGKWTTVLVDDLLPCDKRGHLVYSQAKRKQLWVPLIEKAVAKIHGCYEALVSGRAIEGLATLTGAPCESIPLQASSLPMPSEDELDKDLIWAQLLSSRCVRFLMGASCGGGNMKVDEEEYQQKGLRPRHAYSVLDVKDIQGHRLLKLRNPWGHYSWRGDWSDDSSLWTDDLRDALMPHGASEGVFWISFEDVLNYFDCIDICKVRSGWNEVRLQGTLQPLCS--ISCVLLTVLEPTEAEFTLFQEGQRNSEKSQRSQLDLCVVIFRTRSPAAP--EIGRLVEHSKRQVRGFVGCHKMLERDIYLLVCLAFNHWHTG--------------------------------------------------IEDPHQYPQCILAIHSSKRLLVEQISPSPHLLADAIISLTLTKGQRHEGREGMTAYYLTKGWAGLVVMVENRHENKWIHVKCDCQESYNVVSTRGELKTVDSVPPLQRQVIIVLTQLEGSGGFSIAHRLTHRLANSRGLHDWGPPGATHCPPIEN-VHGLHAPRLIT", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : * * * *.: :* **:: : :*. .: . ** : :. : . ...* . ... : * * . . : . * : . . .. * ... ..:.. .* ::::*: :.* * * . .. . . : . ..* : * . * . :::: :.::::.. :. ..: . . .:: : .... : * *: * ...:* .*:* :*** * : * * .** ***:.:.. *. * .:. * :. . : .: . :* ***** * * * :*: : *:** :* *: :* ** *:**: :**:* ********.* *: : ... : : :* **:****. *:**:* **** **:*****:********** :**:.*::*:.:* :*********** ********:****: * *::***:*:****.*****:**:**.* ** :*****************: ** ** * *: :*.*****::***: . ***************: *:. *********:***:*:** ***:******::**.*.***: . *. .** **.**:******:.: *.:.***.:****::..*:*.*:** : .. : . ***** : **:*****.*.*: : ****:::**: . :***: **** *: **.*. *** . * :** ***** . . : * :**::**: ::** :.. . ****** ** .:*:*********.****:*****:*:***** : ::**.*** :*:*******.*:* ******:***:::*:****..****:***:** * . * ** .. .**.* : . *** ** : ", "identical_positions": 395, "similar_positions": 271, "identity": "23.9%" }, { "cls_id": "homologset.agr.MGI:1355272", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9DC28-1", "uniprot_id": "KC1D_MOUSE", "id": "Q9DC28-1", "name": "Casein kinase I isoform delta", "aln": "MELRVGNRYRLGRKIGSGSFGDIYLGTDIAAGEEVAIKLECVKTKHPQLHIESKIYKMMQGGVGIPTIRWCGAEGDYNVMVMELLGPSLEDLFNFCSRKFSLKTVLLLADQMISRIEYIHSKNFIHRDVKPDNFLMGLGKKGNLVYIIDFGLAKKYRDARTHQHIPYRENKNLTGTARYASINTHLGIEQSRRDDLESLGYVLMYFNLGSLPWQGLKAATKRQKYERISEKKMSTPIEVLCKGYPSEFATYLNFCRSLRFDDKPDYSYLRQLFRNLFHRQGFSYDYVFDWNMLKFG------------------ASRAADDAERERRDREE----------------------RLRHSRNP----ATRGLPSTASGRLRGTQ------------EVAPPTPLTPTSHTANTS-PRPVSGMERE---------RKVSMRLHRGAPVNVSSS---DLTGRQDTSRMSTSQIP--GRVASSGLQSVVHR--------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q06486-1", "uniprot_id": "KC1D_RAT", "id": "Q06486-1", "name": "Casein kinase I isoform delta", "aln": "MELRVGNRYRLGRKIGSGSFGDIYLGTDIAAGEEVAIKLECVKTKHPQLHIESKIYKMMQGGVGIPTIRWCGAEGDYNVMVMELLGPSLEDLFNFCSRKFSLKTVLLLADQMISRIEYIHSKNFIHRDVKPDNFLMGLGKKGNLVYIIDFGLAKKYRDARTHQHIPYRENKNLTGTARYASINTHLGIEQSRRDDLESLGYVLMYFNLGSLPWQGLKAATKRQKYERISEKKMSTPIEVLCKGYPSEFATYLNFCRSLRFDDKPDYSYLRQLFRNLFHRQGFSYDYVFDWNMLKFG------------------ASRAADDAERERRDREE----------------------RLRHSRNP----ATRGLPSTASGRLRGTQ------------EVAPPTPLTPTSHTANTS-PRPVSGMERE---------RKVSMRLHRGAPVNVSSS---DLTGRQDTSRMSTSQIP--GRVASSGLQSVVHR--------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P48730-1", "uniprot_id": "KC1D_HUMAN", "id": "P48730-1", "name": "Casein kinase I isoform delta", "aln": "MELRVGNRYRLGRKIGSGSFGDIYLGTDIAAGEEVAIKLECVKTKHPQLHIESKIYKMMQGGVGIPTIRWCGAEGDYNVMVMELLGPSLEDLFNFCSRKFSLKTVLLLADQMISRIEYIHSKNFIHRDVKPDNFLMGLGKKGNLVYIIDFGLAKKYRDARTHQHIPYRENKNLTGTARYASINTHLGIEQSRRDDLESLGYVLMYFNLGSLPWQGLKAATKRQKYERISEKKMSTPIEVLCKGYPSEFATYLNFCRSLRFDDKPDYSYLRQLFRNLFHRQGFSYDYVFDWNMLKFG------------------ASRAADDAERERRDREE----------------------RLRHSRNP----ATRGLPSTASGRLRGTQ------------EVAPPTPLTPTSHTANTS-PRPVSGMERE---------RKVSMRLHRGAPVNISSS---DLTGRQDTSRMSTSQIP--GRVASSGLQSVVHR--------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6P3K7-1", "uniprot_id": "KC1DB_DANRE", "id": "Q6P3K7-1", "name": "Casein kinase I isoform delta-B", "aln": "MELRVGNRYRLGRKIGSGSFGDIYLGTDISVGEEVAIKLECVKTKHPQLHIESKIYKMMQGGVGIPTIKWCGAEGDYNVMVMELLGPSLEDLFNFCSRKFSLKTVLLLADQMISRIEYIHSKNFIHRDVKPDNFLMGLGKKGNLVYIIDFGLAKKYRDARTHQHIPYRENKNLTGTARYASINTHLGIEQSRRDDLESLGYVLMYFNLGSLPWQGLKAATKRQKYERISEKKMSTPIEVLCKGYPSEFATYLNFCRSLRFDDKPDYSYLRQLFRNLFHRQGFSYDYVFDWNMLKFG------------------ANRTAEEADRERRERDE----------------------RMRHSRNP----AARGIP-AASGRPRPTQ------------DGAPPTPLTPTSHTANTSSPRPVTGMERE---------RKVSMRLHRGAPVNVSSS---DLTGRQDTSRMSTSQNS--IPFDHHGK--------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q7T2E3-1", "uniprot_id": "KC1DA_DANRE", "id": "Q7T2E3-1", "name": "Casein kinase I isoform delta-A", "aln": "MELRVGNRYRLGRKIGSGSFGDIYLGTDITTGEEVAIKLECVKTKHPQLHIESKIYKMMQGGVGIPTIKWCGAEGDYNVMVMELLGPSLEDLFNFCSRKFSLKTVLLLADQMISRIEYIHSKNFIHRDVKPDNFLMGLGKKGNLVYIIDFGLAKKYRDARTHQHIPYRENKNLTGTARYASINTHLGIEQSRRDDLESLGYVLMYFNLGSLPWQGLKAATKRQKYERISEKKMSTPIEVLCKGYPSEFATYLNFCRSLRFDDKPDYSYLRQLFRNLFHRQGFSYDYVFDWNMLKFG------------------GAR--EDPERDRRDREE----------------------RIRQGRIP----LPRVMLPTSSGRPRGTQ------------EVAPAPPLTPDSHT----------GMERE---------RKVSMRLHRGAPVNVSSS---DLTGRQDCSRISTSQAH--SRVP-SGLQSAVPR--------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "O76324-1", "uniprot_id": "DCO_DROME", "id": "O76324-1", "name": "Discs overgrown protein kinase", "aln": "MELRVGNKYRLGRKIGSGSFGDIYLGTTINTGEEVAIKLECIRTKHPQLHIESKFYKTMQGGIGIPRIIWCGSEGDYNVMVMELLGPSLEDLFNFCSRRFSLKTVLLLADQMISRIDYIHSRDFIHRDIKPDNFLMGLGKKGNLVYIIDFGLAKKFRDARSLKHIPYRENKNLTGTARYASINTHLGIEQSRRDDLESLGYVLMYFNLGALPWQGLKAANKRQKYERISEKKLSTSIVVLCKGFPSEFVNYLNFCRQMHFDQRPDYCHLRKLFRNLFHRLGFTYDYVFDWNLLKFG------------------GPRNPQAIQQAQDGADG----------------------QAGHDAVA----AAAAVAAAAAASSHQQQQHKVNAALGGGGGSAAQQQLQGGQTLAMLGGNGGGNGSQLI---------GGNGLNMDDSMAATNSSRPPYDTPERRPSIRMRQGGGGGGGGVGVGGMPSGGGGGGVGNAK-", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P29295-1", "uniprot_id": "HRR25_YEAST", "id": "P29295-1", "name": "Casein kinase I homolog HRR25", "aln": "MDLRVGRKFRIGRKIGSGSFGDIYHGTNLISGEEVAIKLESIRSRHPQLDYESRVYRYLSGGVGIPFIRWFGREGEYNAMVIDLLGPSLEDLFNYCHRRFSFKTVIMLALQMFCRIQYIHGRSFIHRDIKPDNFLMGVGRRGSTVHVIDFGLSKKYRDFNTHRHIPYRENKSLTGTARYASVNTHLGIEQSRRDDLESLGYVLIYFCKGSLPWQGLKATTKKQKYDRIMEKKLNVSVETLCSGLPLEFQEYMAYCKNLKFDEKPDYLFLARLFKDLSIKLEYHNDHLFDWTMLRYTKAMVEKQRDLLIEKGDLNANSNAASASNSTDNKSETFNKIKLLAMKKFPTHFHYYKNEDKHNPSPEEIKQQTILNNNAASSLPEELLNALDKGMENLRQQQPQQQVQSSQPQPQPQQLQQQPNGQRPNYYPEPLLQQQQRDSQEQQQQVPMATTRATQYPPQINSNNFNTNQASVPPQMRSNPQQPPQDKPAGQSIWL", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*:****.::*:************* ** : *********.::::****. **:.*: :.**:*** * * * **:**.**::***********:* *:**:***::** **:.**:***.:.*****:********:*::*. *::*****:**:** .: :********.*********:*********************:** *:********:.*:***:** ***:...: .**.* * ** *: :*:.::**::*** .* :**::* : : *::***.:*:: . .. . . :. . : ::. . : . . : . . :: : . : .: . . ", "identical_positions": 183, "similar_positions": 108, "identity": "37.04%" }, { "cls_id": "homologset.agr.MGI:1355274", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P15374-1", "uniprot_id": "UCHL3_HUMAN", "id": "P15374-1", "name": "Ubiquitin carboxyl-terminal hydrolase isozyme L3", "aln": "--MEGQRWLPLEANPEVTNQFLKQLGLHPNWQFVDVYGMDP-ELLSMVPRPVCAVLLLFPITEKYEVFRTEEEEKIKSQGQDVTSSVYFMKQTISNACGTIGLIHAIANNKDKMHFESGSTLKKFLEESVSMSPEERARYLENYDAIRV----THETSAHEGQTEAPSIDEKVDLHFIALVHVDGHLYELDGRKP----FPINHGETSDETLLEDAIEVCKKFMERDPDE---LRFNAIALSAA--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9JKB1-1", "uniprot_id": "UCHL3_MOUSE", "id": "Q9JKB1-1", "name": "Ubiquitin carboxyl-terminal hydrolase isozyme L3", "aln": "--MEGQRWLPLEANPEVTNQFLKQLGLHPNWQFVDVYGMEP-ELLSMVPRPVCAVLLLFPITEKYEVFRTEEEEKIKSQGQDVTSSVYFMKQTISNACGTIGLIHAIANNKDKMHFESGSTLKKFLEESVSMSPEERAKFLENYDAIRV----THETSAHEGQTEAPSIDEKVDLHFIALVHVDGHLYELDGRKP----FPINHGKTSDETLLEDAIEVCKKFMERDPDE---LRFNAIALSAA--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q91Y78-1", "uniprot_id": "UCHL3_RAT", "id": "Q91Y78-1", "name": "Ubiquitin carboxyl-terminal hydrolase isozyme L3", "aln": "--MEGQRWLPLEANPEVTNQFLKQLGLHPNWQFVDVYGMEP-ELLSMVPRPVCAVLLLFPITEKYEVFRTEEEEKIKSQGQDVTSSVYFMKQTISNACGTIGLIHAIANNKDKMHFESGSALKKFLEESVAMSPEERARHLENYDAIRV----THETSAHEGQTEAPSIDEKVDLHFIALVHVDGHLYELDGRKP----FPINHGKTSDETLLEDAIEVCKKFMERDPDE---LRFNAIALSAA--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P35122-1", "uniprot_id": "UCHL_DROME", "id": "P35122-1", "name": "Ubiquitin carboxyl-terminal hydrolase", "aln": "----MLTWTPLESNPEVLTKYIHKLGVSPAWSVTDVIGLED-DTLEWIPRPVKAFILLFPCSETYEKHRAEEHDRIKEVEEQHPEDLFYMRQFTHNACGTVALIHSVANNKE-VDIDRG-VLKDFLEKTASLSPEERGRALEKDEKFTA----DHEALAQEGQTNAAN-HEKVIHHFIALVNKEGTLYELDGRKS----FPIKHGPTSEETFVKDAAKVCKEFMARDPNE---VRFTVLALTAAQQ", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P35127-1", "uniprot_id": "UBL1_YEAST", "id": "P35127-1", "name": "Ubiquitin carboxyl-terminal hydrolase YUH1", "aln": "MSGENRAVVPIESNPEVFTNFAHKLGLKNEWAYFDIYSLTEPELLAFLPRPVKAIVLLFPINE--------DRKSSTSQQITSSYDVIWFKQSVKNACGLYAILHSLSNNQS--LLEPGSDLDNFLKSQSDTSSSKNRFDDVTTDQFVLNVIKENVQTFSTGQSEAPEATADTNLHYITYVEENGGIFELDGRNLSGPLYLGKSDPTATDLIEQELVRVRVASYMENANEEDVLNFAMLGLGPNWE", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *:*:**** .:: ::**: * *: .: : * :**** *.:**** .* :.. .. . .: :::* **** .::*:::**:. :: * *..**:. *..:. . : : : **::*.. .. *:*: *. :* ::*****: : : . *: : : :: .* .:.:* :.* :.* . ", "identical_positions": 51, "similar_positions": 80, "identity": "20.73%" }, { "cls_id": "homologset.agr.MGI:1355275", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZRI4-1", "uniprot_id": "D3ZRI4_RAT", "id": "D3ZRI4-1", "name": "", "aln": "--MSYPQFGYP-YSSAPQFLMTTN--------------------------------------------------------------------------------------------------------SLSTCCESGGRTLADSGPAASAQAPVYCPVYESRLLATARHELNSAAA---LGVYGSPYSSSQGYGNYVTYGSEASAFYS--LNSFESKDGTG----SSHAGLPPTAAAAYYPYEPTLGQYPYDRYG------TVDSGTRRKNATRETTSTLKAWLQEHRKNPYPTKGEKIMLAIITKMTLTQVSTWFANARRRLKKENKMTWPPRNKCADEKRPYGEGEEEEAGEEESREEPLKSVKSEGPAGKEDKELELSDLEDFDPLDTET--SECELKTPFQPLDSVPERIPPSSDGPGTGKEAPVTLRMPLGTADGAVMDGDLERARNCLRSTVVAPD--------SGAEGGPQACEAKLTFAPAGAPPNLETKPRIWSLAHTAT---------------AAAATALSQTEFPSCMLKRQGSTGASAVT--PASSPAVPAA--SGTLDRHQDSPVTSLRNWVDGVFHDPILRHSTLNQAWATA----------------------------------------------------KGALLDPGPLGRNLGAGTNVLTTPLACSFRPTVPQDVSPAGASRELLATPKASGKPFCT---------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9QY61-1", "uniprot_id": "IRX4_MOUSE", "id": "Q9QY61-1", "name": "Iroquois-class homeodomain protein IRX-4", "aln": "--MSYPQFGYP-YSSAPQFLMTTN--------------------------------------------------------------------------------------------------------SLSTCCESGGRTLADSGPAASAQAPVYCPVYESRLLATARHELNSAAA---LGVYGSPYGSSQGYGNYVTYGSEASAFYS--LNSFESKDGTG----SSHAGLPPTAAAAYYPYEPALSQYPYDRYG------TVDSGTRRKNATRETTSTLKAWLQEHRKNPYPTKGEKIMLAIITKMTLTQVSTWFANARRRLKKENKMTWPPRNKCADEKRPYGEGEEEEAGEEESREEPLKSAKSEGHAGKDDKELELSDLEDFDPLDAET--SECELKTPFQSLDSGPERIPASSDGPGTGKEASTTLRMPLGTAGGAVMDGDLERARNCLRSTVVVPD--------SGAEGGPPACEAKLTFAQAGAPPNLETKPRIWSLAHTAT---------------AAAATALSQTEFPSCMLKRQGPTGVSATT--PASSPAVTAP--SGALDRHQDSPVTSLRNWVDGVFHDPILRHSTLNQAWATA----------------------------------------------------KGALLDPGPLGRNLGAGTNVLTTPLACSFPPTVPQDVPPAGASRELLATPKAGGKPFCT---------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P78413-1", "uniprot_id": "IRX4_HUMAN", "id": "P78413-1", "name": "Iroquois-class homeodomain protein IRX-4", "aln": "--MSYPQFGYP-YSSAPQFLMATN--------------------------------------------------------------------------------------------------------SLSTCCESGGRTLADSGPAASAQAPVYCPVYESRLLATARHELNSAAA---LGVYGGPYGGSQGYGNYVTYGSEASAFYS--LNSFDSKDGSG----SAHGGLAP-AAAAYYPYEPALGQYPYDRYG------TMDSGTRRKNATRETTSTLKAWLQEHRKNPYPTKGEKIMLAIITKMTLTQVSTWFANARRRLKKENKMTWPPRNKCADEKRPYAEGEEEEGGEEEAREEPLKSSKNAEPVGKEEKELELSDLDDFDPLEAEP--PACELKPPFHSLDGGLERVPAAPDGP--VKEASGALRMSLAAGGGAALDEDLERARSCLRSAAAGPEPL------PGAEGGPQVCEAKLGFVPAGASAGLEAKPRIWSLAHTATAA-------------AAAATSLSQTEFPSCMLKRQGPAAPAAVSSAPATSPSVALPH-SGALDRHQDSPVTSLRNWVDGVFHDPILRHSTLNQAWATA----------------------------------------------------KGALLDPGPLGRSLGAGANVLTAPLARAFPPAVPQDAPAAGAARELLALPKAGGKPFCA---------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9PJE4-1", "uniprot_id": "A0A8M9PJE4_DANRE", "id": "A0A8M9PJE4-1", "name": "", "aln": "--MSYPQFGYP-YSSAPQFLMTTN--------------------------------------------------------------------------------------------------------SLTSCCESSTRSIPDS----SAQTPVYCPVYESRLLATARHELSSAAA---LGVYGSPYTGGQGYGNYVTYGADASAFYS--LGTFDAKDGSA----SAHAGITP--AAAYYPYDPTLGQYQYDRYG------SMEGGTRRKNATRETTSTLKAWLQEHRKNPYPTKGEKIMLAIITKMTLTQVSTWFANARRRLKKENKMTWPPRNKGSDEKK-YDD-DEDGSPEEQIKSETNDDAESKD---REDKDLQLSDLEDFDPLESES--PECELKHRFQ-----------------------ISAHMETKDPQKLSIPGLLEEAKSCLKS----PE---------DCELELRHSKACFQQQQQQSHPILDSKPRIWSLAQTAT--------------------SLNPAEFPSCMLR----------------CPASPSP--AGGPDRQQDSPVTTLRNWVDGVFHDPLFRHSSLNQTNTTVSWT------------------------------------------------NKGSILETGALGRSV--------------------ADSGKQEAGKDTMTFPKGVNKIFCS---------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q1LWG1-1", "uniprot_id": "Q1LWG1_DANRE", "id": "Q1LWG1-1", "name": "", "aln": "--MSFTQFGYS-YPAAPQLLMSSN--------------------------------------------------------------------------------------------------------ALSTCFESSG-SLLDSGVPTSPQNSLYCPVYESRLVASSRHELIPTA------VYGNSCSKNHVYDSCSTYGPDSAACYP--LGKLNEKDGVQ----TGHSRVTQ--SSAYYPYDYPIGQYSYDRYGY----GSVDVGTRRKNATRETTSTLKAWLQEHKKNPYPTKGEKIMLAIITKMTLTQVSTWFANARRRLKKENKMTWSPRNKNSDEKECDDDQEDLDEAQEEPIKTEQDFNDNHG---KDDTDQLHSDLDDFDLVESDG--SECESKPSFV-----------------------VHVHSETSDHPETHFKDAFHESVTELTRGVHKFS--------EDRLRAPAEDHQMAKFYLQQGQKTIETKPKIWSLAQTAT--------------------SLNQVDYSSCMHKR-------------TACPSSNCDSDSEMTKRKQESPVATLRNWVDGVFHDPLFRHNNLNQTFSNS------------------------------------------------------TELWTDAI---------------------------SSQNNYHEHSGTPITSSHA------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q24248-1", "uniprot_id": "ARA_DROME", "id": "Q24248-1", "name": "Homeobox protein araucan", "aln": "-MAAYTQFGYGGFPSASQLLPPSVQTTEDASANVNVNVNEALVMTNAPAMSPTGGQDCQGSQPSGGAGGDASSGALSPNALSQNSNAATVVGAGGGSSAGGGGPADLATGGSLDGNGVGTTPTAGGAGGGGSCCENGRPIMTDP---VSGQTVCSCQYDSARLALSSYSRLPAAS----VGVYGTPYPSTD-QNPYQSIGVDSSAFYSPLSNPYGLKDTGAGPEMGAWTSAGLQPTTGYYSYDP-MSAYGGLLVSNSSYGASYDLAARRKNATRESTATLKAWLNEHKKNPYPTKGEKIMLAIITKMTLTQVSTWFANARRRLKKENKMTWEPKNRTDDDDDALVSDDEKDKEDLEPSKGSQGSVS----LAKDETKEEEDAIDE--DQKCLG--QANILRAGFGYPSAGSGSGGYPGGGGSSS---GHPGGYHPYHHQHPAYYQAGQQGG---MLPFHGENS----------KLQTDLGDPKNQLGRDCGVPIPATKPKIWSLADTVGCKTPPP--AYMGHQSMPLQQQQQQQQQQQQAQHQYPPSEAGRDQQLFNGAAAPYLRPHTTAYGGFLGATTQQLHTTNNSIPYSNMPPQQQQPQQQQQQLQQGGTIHTTGSSSGPIIPLQFHNRHPQQQQQLQQQSQSTASQRAMGFLEAQPDTPPQTPPNMKVLS--------GALSLLPTATQVPMTATCRSSNAFGFPASGYPMNFSARLGEYSPRDDYSSGNSSSSSSSSPQLQRNEAMFKPLFKKFTN--------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P54269-1", "uniprot_id": "CAUP_DROME", "id": "P54269-1", "name": "Homeobox protein caupolican", "aln": "-MAAYAQFGYAGYPTANQLTTANTDSQSGHGG------GSPLSGTNEASLSPSGGSTATG----------LTAGPLSPGAVSQSSHHA---GHKGLSTS----PAEDVVGGDVP---VGLSSAAQDLPSRGSCCENGRPIITDP---VSGQTVCSCQYDPARLAIGGYSRMALPSGGVGVGVYGGPYPSNE-QNPYPSIGVDNSAFYAPLSNPYGIKDTSPSTEMSAWTSASLQSTTGYYSYDPTLAAYG--------YGPNYDLAARRKNATRESTATLKAWLSEHKKNPYPTKGEKIMLAIITKMTLTQVSTWFANARRRLKKENKMTWEPKNKTEDDDDGMMSDDEKEKDAGDGGKLSTEAFDPGNQLIKSELGKAEKEVDSSGDQKLDLDREPHNLVAMRGLAPYATPPGAHPMHAAYSSYAQSHNTHTHPHPQQMQHHQQQQQQQQNQQQLQHHQMDQPYYHPGGYGQEESGEFAAQKNPLSRDCGIPVPASKPKIWSVADTAACKTPPPTAAYLGQNFYPPSSADQQLPHQPLQQHQQQQLQQLQQQQQHHHHPHHHHPHHSMELG----SPLSMMSSYAGGSPYSRIPTAYTEAMGMHLPSSS-----SSSSSTGKLPPTHIH---PAPQR--------------VGFPEIQPDTPPQTPPTMKLNSSGGSSSSSGSSHSSSMHSVTPVTVASMVNILYSNTDSGYGHGHSHGHGHG---HGHGLGHGHGLGHGHGHMGVTSNAYLTEGGRSGS--------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "M9PI45-1", "uniprot_id": "M9PI45_DROME", "id": "M9PI45-1", "name": "", "aln": "MTVHSNETGICLVMNAVSTHLATSSPNTPPTNAPQSPPSTLPTLACPAAQPLSAPGIAGPG--------------HSGMVTSTVPPGARSTSPCGPSAGLPALSLVGAPPPGPHSSAPGGAPAPGAGNPPNRCCDTGRTIYTDP---VSGQTICSCQYDMLN-----YQRLAAAGG------VPLGVYPEGMSAYLSGIAADQPPFYAN-PAGIDLKENLVAG------ASPWPYPSMYHPYDAAFAGYPFNSYG------MDLNGARRKNATRETTSTLKAWLNEHKKNPYPTKGEKIMLAIITKMTLTQVSTWFANARRRLKKENKMTWEPRNRVDDDDANIDDDDDKNTEDNDLLDAKDSGVGSTD--DKDRSGRLGDMMTDRPGESNNSEWSESRPGSPNGSPDLYDRPGSMPPGAHPLFHPAALHHHFRPPAGSPPDIAAYHHHQQQLLQQHQQAQQNS--LQTAVGGTAKPRIWSLADMASKDSKDSSSGAKDNHPELPPAHPGFYGHP---------GQQPSPGKILSPLAARIPNYSPYVRPDLYRGFYGPAAAHLGAPTQEFLEHQRTFGASLAAHNGPLGMNPLLWKAAVSGAANGHHFAPLSLTTSGGSSGG---------------------------------QQVAPPPVASPSASSSSSSMGCDVVHIPTSSGQSAAQHMMGPISSNSTASSSSSHSGKISPGVNVTSLSAKPXHPSAASPDPELGAAPIASPISAFRSLIAFREQQKLTLLRP", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : * * . .. * :.. *. * * * . .: .. . : .. *. *: .: *:.*: :. * .:********:*:******.**:******************************************* *:*: *:. . :: : . :. . : . . .. . :* . .:. : . . : : : . . : . . . . ", "identical_positions": 76, "similar_positions": 68, "identity": "9.88%" }, { "cls_id": "homologset.agr.MGI:1355285", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZSG3-1", "uniprot_id": "D3ZSG3_RAT", "id": "D3ZSG3-1", "name": "", "aln": "---------------------------------------------------------------------------------------MSSYQKELEKYRDIDEDEILRTLSPEELEQLDCELQEMDPENMLLPAGLRQRDQTKKSPTGPLDRDALLQYLEQQALEVKERDDLVPFTG-EKKGKPFIQP---KREIPAQEQITLEP--ELEEALSHATDAEMCDIAAILGMYTLMSNKQYYDAICSGEICNTEGISSVVQPDKYKPVPDEPPNPTNIEEMLKRVRSNDKELEEVNLNNIQDIPIPVLSDLCEAMKTNTYVRSFSLVATKSGDPIANAVADMLRENRSLLSLNIESNFISSTGLMAVLKAVRENATLTELRVDNQR-QWPGDAVEMEMATVLEQCPSIVRFGYHFTQQGPRARAANAMTRNNE-LRRQQKKR----------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9JLH8-1", "uniprot_id": "TMOD4_MOUSE", "id": "Q9JLH8-1", "name": "Tropomodulin-4", "aln": "---------------------------------------------------------------------------------------MSSYQKELEKYRDIDEDEILRTLSPEELEQLDCELQEMDPENMLLPAGLRQRDQTKKSPTGPLDRDALLQYLEQQALEVKERDDLVPYTG-EKKGKPFIQP---KREIPAQEQITLEP--ELEEALSHATDAEMCDIAAILGMYTLMSNKQYYDAICSGEICNTEGISSVVQPDKYKPVPDEPPNPTNIEEMLKRVRSNDKELEEVNLNNIQDIPIPVLSDLCEAMKTNTYVRSFSLVATKSGDPIANAVADMLRENRSLQSLNIESNFISSTGLMAVLKAVRENATLTELRVDNQR-QWPGDAVEMEMATVLEQCPSIVRFGYHFTQQGPRARAAHAMTRNNE-LRRQQKKR----------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9NZQ9-1", "uniprot_id": "TMOD4_HUMAN", "id": "Q9NZQ9-1", "name": "Tropomodulin-4", "aln": "---------------------------------------------------------------------------------------MSSYQKELEKYRDIDEDEILRTLSPEELEQLDCELQEMDPENMLLPAGLRQRDQTKKSPTGPLDREALLQYLEQQALEVKERDDLVPFTG-EKKGKPYIQP---KREIPAEEQITLEP--ELEEALAHATDAEMCDIAAILDMYTLMSNKQYYDALCSGEICNTEGISSVVQPDKYKPVPDEPPNPTNIEEILKRVRSNDKELEEVNLNNIQDIPIPMLSELCEAMKANTYVRSFSLVATRSGDPIANAVADMLRENRSLQSLNIESNFISSTGLMAVLKAVRENATLTELRVDNQR-QWPGDAVEMEMATVLEQCPSIVRFGYHFTQQGPRARAAQAMTRNNE-LRRQQKKR----------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A0B4K6N4-1", "uniprot_id": "A0A0B4K6N4_DROME", "id": "A0A0B4K6N4-1", "name": "", "aln": "MSDIEDVFGGSAEETKPEPDAQSKTSVVTEHTEEVIPGETEKMVTETIDEDGDVVEETTEVTRKTVKRTMKITETSATTKTTTLTTPAKLYGKDLSEYDDVDVESLLAQLSPE---EITILAKEVDPDDNFLPPDQRNSYECTKEATGPLNRKQLIEHINKQAIETPDQPEFEPFVQGKVRGKKWVPPPRDARDIEAEEQIAIDMGEEYEHALNDATQEEIIDLAAILGFHSMMNQDQYHASLLNKGQPVGLGWDGITKSTQQKLFPMDPPNNTDVEESIKRVKDDDSKLIDLNLNNIKNISDEKLEQLFAALPQNEHLEVLSLTNVGLTDKTALLLAAAIEKSKTLRVLNVETNFISPPVIVKLVQALLKCHTIEEFRASNQRSAVLGNKIEMEITDLVEKNSSLLRLGLHLEFNDARHRVAAHLQRNIDRIFRVQKLKPNLPKLILPGNMEIERDLVAYNRSATPSPSPSPQPPVDYEVEEDPDNMVIRGGGDAFDPDVDPDNMVVPGSRSVTPNYDDEGVYQAHTWTSASHGPSDQELHRWRLAVGFIRLGLGSLHILHRKKSIAYQ", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . * *:*.:* *:* :.:* **** :: :*:**:: :**.. *: : .*..****:*. *::::::**:*. :: :: *:. : :** :: * *:* *:***::: * *.** .**: *: *:****.::::*.:.**: :: . * ..:.:. : * .* :*** *::** :***:.:*.:* ::*****::*. *.:* *: * ::. :**. . * * :* :.:.::* **:*:****.. :: :::*: : *: *:*..*** *: :***:: ::*: .*::*:* *: :..* *.* : ** : : * ** : ", "identical_positions": 113, "similar_positions": 137, "identity": "19.82%" }, { "cls_id": "homologset.agr.MGI:1355292", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "M0R8P5-1", "uniprot_id": "M0R8P5_RAT", "id": "M0R8P5-1", "name": "Interleukin-17 receptor B", "aln": "MLLVLLSLAAMCRSALSREPTIQCGSETGPSPEWMVQHTLTPGDLRDLRVELVKTSVATEEFSILMNISWILRADASIRLLKATKICVSGKNNMHSYSCVRCNYTETFQSQTRPSGGKWIFSYVGFPVELSTLYLIGAHNIPNANMNEDSPSLSVNFTSPGCLNHVMKYKKQCIEAGSLWDPNITACKKNEKTVEVNFTTNSLGNRYMVLIRRDTMLGVSIVLEN---KLTRTSVVIPVNDESEGALVELTPYLHTCDNDCIRRKGTVVLCSETSAPFPPDDNRSMLRGWLPLLLV-LLVATWVLAVGIYLTWRQGRSTKTSFPITAMLLPLVKVLVVYPSEICFHHTVCRFTDFLQNYCRSEVILEKWQKKKIAEMGPVQWLTTQKQAADKVVFLLPSDAPSLCDSACGHKEGSATENSQDLFPLAFNLFCSDFSSQTHLHKYLVVYLGGADLKGDYNALRVCPQYHLMKDAPAFHTELLKATQSMPLKKRPQACHGSCSPL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9JIP3-1", "uniprot_id": "I17RB_MOUSE", "id": "Q9JIP3-1", "name": "Interleukin-17 receptor B", "aln": "MLLVLLILAASCRSALPREPTIQCGSETGPSPEWMVQHTLTPGDLRDLQVELVKTSVAAEEFSILMNISWILRADASIRLLKATKICVSGKNNMNSYSCVRCNYTEAFQSQTRPSGGKWTFSYVGFPVELSTLYLISAHNIPNANMNEDSPSLSVNFTSPGCLNHVMKYKKQCTEAGSLWDPDITACKKNEKMVEVNFTTNPLGNRYTILIQRDTTLGFSRVLEN---KLMRTSVAIPVTEESEGAVVQLTPYLHTCGNDCIRREGTVVLCSETSAPIPPDDNRRMLGGWLPLFLV-LLVAVWVLAAGIYLTWRQGRSTKTSFPISTMLLPLIKVLVVYPSEICFHHTVCRFTDFLQNYCRSEVILEKWQKKKIAEMGPVQWLTTQKQAADKVVFLLPSDVPTLCDSACGHNEGSARENSQDLFPLAFNLFCSDFSSQTHLHKYLVVYLGGADLKGDYNALSVCPQYHLMKDATAFHTELLKATQSMSVKKRSQACHDSCSPL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9NRM6-1", "uniprot_id": "I17RB_HUMAN", "id": "Q9NRM6-1", "name": "Interleukin-17 receptor B", "aln": "MSLVLLSLAALCRSAVPREPTVQCGSETGPSPEWMLQHDLIPGDLRDLRVEPVTTSVATGDYSILMNVSWVLRADASIRLLKATKICVTGKSNFQSYSCVRCNYTEAFQTQTRPSGGKWTFSYIGFPVELNTVYFIGAHNIPNANMNEDGPSMSVNFTSPGCLDHIMKYKKKCVKAGSLWDPNITACKKNEETVEVNFTTTPLGNRYMALIQHSTIIGFSQVFEPHQKKQTRASVVIPVTGDSEGATVQLTPYFPTCGSDCIRHKGTVVLCPQTGVPFPLDNNKSKPGGWLPLLLLSLLVATWVLVAGIYLMWRHERIKKTSFS-TTTLLPPIKVLVVYPSEICFHHTICYFTEFLQNHCRSEVILEKWQKKKIAEMGPVQWLATQKKAADKVVFLLSNDVNSVCDGTCGKSEGSPSENSQDLFPLAFNLFCSDLRSQIHLHKYVVVYFREIDTKDDYNALSVCPKYHLMKDATAFCAELLHVKQQVSAGKRSQACHDGCCSL", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* **** *** ****:.****:*************:** * *******:** *.****: ::*****:**:*****************:**.*::***********:**:********* ***:******.*:*:*.************.**:**********:*:*****:* :*******:********: *******..***** **::.* :*.* *:* * *:**.***. :**** *:****: **..****::******.:*..*:* *:*: *****:*: ****.***..**** **: * .****. :: *** :***************:* **:****:************************:***:*********..*. ::**.:**:.***. *****************: ** *****:***: * *.***** ***:*******.** :***:..*.:. **.****..*..*", "identical_positions": 356, "similar_positions": 99, "identity": "70.78%" }, { "cls_id": "homologset.agr.MGI:1355294", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q64335-1", "uniprot_id": "KLRG1_RAT", "id": "Q64335-1", "name": "Killer cell lectin-like receptor subfamily G member 1", "aln": "MADNSIYSTLELPAAPRVQDDSRWKVKAVLHRPCVSYLVMVALGLLTVILMSLLLYQRTLCCGSKGFMCSQCSRCPNLWMRNGSHCYYFSMEKRDWNSSLKFCADKGSHLLTFPDNQGVNLFQEYVGEDFYWIGLRDIDGWRWEDGPALSLS-ILSNSVVQKCGTIHRCGLHASSCEVALQWICEKVLP------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O88713-1", "uniprot_id": "KLRG1_MOUSE", "id": "O88713-1", "name": "Killer cell lectin-like receptor subfamily G member 1", "aln": "MADSSIYSTLELPEAPQVQDESRWKLKAVLHRPHLSRFAMVALGLLTVILMSLLMYQRILCCGSKDSTCSHCPSCPILWTRNGSHCYYFSMEKKDWNSSLKFCADKGSHLLTFPDNQGVKLFGEYLGQDFYWIGLRNIDGWRWEGGPALSLR-ILTNSLIQRCGAIHRNGLQASSCEVALQWICKKVLY------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q96E93-1", "uniprot_id": "KLRG1_HUMAN", "id": "Q96E93-1", "name": "Killer cell lectin-like receptor subfamily G member 1", "aln": "MTDSVIYSMLELPTATQAQNDYGPQQKSSSSRPSCSCLVAIALGLLTAVLLSVLLYQWILCQGSNYSTCASCPSCPDRWMKYGNHCYYFSVEEKDWNSSLEFCLARDSHLLVITDNQEMSLLQVFLSEAFCWIGLRNNSGWRWEDGSPLNFSRISSNSFVQTCGAINKNGLQASSCEVPLHWVCKKCPFADQALF", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*:*. *** **** *.:.*:: : *: ** * :. :******.:*:*:*:** ** **: *: *. ** * : *.******:*::******:** :.****.:.*** :.*: ::.: * *****: .*****.*..*.: * :**.:* **:*:: **:******.*:*:*:* ", "identical_positions": 91, "similar_positions": 56, "identity": "46.67%" }, { "cls_id": "homologset.agr.MGI:1355295", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9JL35-1", "uniprot_id": "HMGN5_MOUSE", "id": "Q9JL35-1", "name": "High mobility group nucleosome-binding domain-containing protein 5", "aln": "MPKRKAAG--DVSQEPKRRSARLSAMPVPFTPELKPKRASTSRKTKT-TNVVEENKDASTIPIPETKPEDVKDECNMENAENGEAKIMEAPIPKMEAEEVKEQINEDTEEDGGEKKEAVAAEAKDDELKANIQDVEKDEDGKEHKDTGEEVEDGKIEEEGLNEKPGTAKSEDAEVSKDEEEKGDNEKGEDGKEEGDEKEEEKDDKEGDTGTEKEVKEQNKEAEE-DDGKCKEEENKEVGKEGQPEEDGKEDLHEEVGKEDLHEEDGKEGQPEEDGKEIHHEEDGKEGQPEEDGKEYLHEEDG------EEGQP------------KEDQKEGQPEEDGKEDQPEEDGKEGQCKEDGKEGHHEEGGKEDLHEEDGKE---------KDGGKEDRKEEGEQEVAVDEGSDENKVEAEEEGAENKDFKQDGEKEEPLSIV", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "B4F777-1", "uniprot_id": "HMGN5_RAT", "id": "B4F777-1", "name": "High mobility group nucleosome-binding domain-containing protein 5", "aln": "MPKRKAAG--DASQEPKRRSARLSAMPVPFTPELKPKRASTSRKTKT-TNVVEESKDAGATTIPETKPEVVKGECNMENAENGEAKIIEAPISKMETEEVKEQINEDTEGDGGEKKEAVVTKGKNDELEANIQDVEKDEDEKEHEDTGEEGEDGEREG-GLKEKPDVAEIEDAKEAKDDEEKEDKEK-EDDKGGDGKKEEEKDD-EGEAETEEEVKEQQKEETEGDDGKCKVEENKEGRKESQHEEEGKEELHEEDGKEDLHEEDGKEDLHEEDGKEDLHEEEGKEDLHEEEGKEDLHEEEGKEDLHEEEGKEDLHEEEGKEDLHEEEGKEDLHEEEGKEDLHEEDGKEGQHEEEGKEDLHEEEGKEDLHEEDGKEGQHEEDGKKKADGNEDRKEEEEQEAAT-EGNDENKVEVEEE-ADNKDFKEDGEKGEPVSTV", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P82970-1", "uniprot_id": "HMGN5_HUMAN", "id": "P82970-1", "name": "High mobility group nucleosome-binding domain-containing protein 5", "aln": "MPKRKAAGQGDMRQEPKRRSARLSAMLVPVTPEVKPKRTSSSRKMKTKSDMMEENIDTSAQAVAETKQEAVVEEDYNENAKNGEAKITEAPASEKEIVEVKEENIEDATEKGGEKKEAVAAEVKNEEEDQ--KEDEEDQNE-EKGEAGKEDKDEKGEEDGKEDKNGNEKGEDAKE------KEDGKKGEDGKGNG------------------------------EDGKEKGEDEKE-------EEDRKE------------TGDGKEN---EDGKEKGDKKEGKDVKVKEDEKE---------------------------------------REDGKED---EGGNE---EEAGKE-------KEDLKEE------------------EEGKEEDE---------------IKED---------DGKKEEPQSIV", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "******** * ************* **.***:****:*:*** ** ::::**. *:.: .:.*** * * * ***:****** *** .: * ****: **: .********.:: *::* . :: *:*:: *: ::*:* :* : * * ::* . : ***: * * :* **.* . :*** * *::** **: ** ****. ***** .:::**: :*: ** .*:**** *.*:* :* *** ****:** *: *** * :*: **:* ** * *", "identical_positions": 149, "similar_positions": 68, "identity": "34.1%" }, { "cls_id": "homologset.agr.MGI:1355296", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9JK66-1", "uniprot_id": "PRKN_RAT", "id": "Q9JK66-1", "name": "E3 ubiquitin-protein ligase parkin", "aln": "-----------------------------MIVFVRFNSSYGFPVEVDSDTSIFQLKEVVAKRQGVPADQLRVIFAGKELQNHLTVQNCDLEQQSIVHIVQRPQRKSHETNASGGDKPQSTPEGSIWEPRSLTRVDLSSHILPADSVGLAVILDTDSKSDSEAARGPEAKPTYHSFFVYCKGPCHKVQPGKLRVQCGTCRQATLTLAQGPSCWDDVLIPNRMSGECQSPDCPGTR--------AEFFFKCGAHPTS-DKDTSVALNLITNNSRSIPCIACTDVRNPVLVFQCNHRHVICLDCFHLYCVTRLNDRQFVHDAQLGYSLPCVAGCPNSLIKELHHFRILGEEQYNRYQQYGAEECVLQMGGVLCPRPGCGAGLLPEQGQKKVTCE-GGNGLGCGFVFCRDCKEAYHEGECDSMFE-ASGATSQAYRVDQRAAEQARWEEASKETIKKTTKPCPRCNVPIEKNGGCMHMKCPQPQCKLEWCWNCGCEWNRACMGDHWFDV", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9WVS6-1", "uniprot_id": "PRKN_MOUSE", "id": "Q9WVS6-1", "name": "E3 ubiquitin-protein ligase parkin", "aln": "-----------------------------MIVFVRFNSSYGFPVEVDSDTSILQLKEVVAKRQGVPADQLRVIFAGKELPNHLTVQNCDLEQQSIVHIVQRPRRRSHETNASGGDEPQSTSEGSIWESRSLTRVDLSSHTLPVDSVGLAVILDTDSKRDSEAARGP-VKPTYNSFFIYCKGPCHKVQPGKLRVQCGTCKQATLTLAQGPSCWDDVLIPNRMSGECQSPDCPGTR--------AEFFFKCGAHPTS-DKDTSVALNLITSNRRSIPCIACTDVRSPVLVFQCNHRHVICLDCFHLYCVTRLNDRQFVHDAQLGYSLPCVAGCPNSLIKELHHFRILGEEQYTRYQQYGAEECVLQMGGVLCPRPGCGAGLLPEQGQRKVTCE-GGNGLGCGFVFCRDCKEAYHEGDCDSLLE-PSGATSQAYRVDKRAAEQARWEEASKETIKKTTKPCPRCNVPIEKNGGCMHMKCPQPQCKLEWCWNCGCEWNRACMGDHWFDV", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O60260-1", "uniprot_id": "PRKN_HUMAN", "id": "O60260-1", "name": "E3 ubiquitin-protein ligase parkin", "aln": "-----------------------------MIVFVRFNSSHGFPVEVDSDTSIFQLKEVVAKRQGVPADQLRVIFAGKELRNDWTVQNCDLDQQSIVHIVQRPWRKGQEMNATGGDDPRNAAGGCEREPQSLTRVDLSSSVLPGDSVGLAVILHTDSRKDSPPAGSPAGRSIYNSFYVYCKGPCQRVQPGKLRVQCSTCRQATLTLTQGPSCWDDVLIPNRMSGECQSPHCPGTS--------AEFFFKCGAHPTS-DKETSVALHLIATNSRNITCITCTDVRSPVLVFQCNSRHVICLDCFHLYCVTRLNDRQFVHDPQLGYSLPCVAGCPNSLIKELHHFRILGEEQYNRYQQYGAEECVLQMGGVLCPRPGCGAGLLPEPDQRKVTCE-GGNGLGCGFAFCRECKEAYHEGECSAVFE-ASGTTTQAYRVDERAAEQARWEAASKETIKKTTKPCPRCHVPVEKNGGCMHMKCPQPQCRLEWCWNCGCEWNRVCMGDHWFDV", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AB13ABF7-1", "uniprot_id": "A0AB13ABF7_DANRE", "id": "A0AB13ABF7-1", "name": "E3 ubiquitin-protein ligase parkin", "aln": "-----------------------------MIVFVRFNSSHGFPVELEQGASVSELKEAVGRLQGVQSDQLRVIFAGRELCNESTLQGCDLPEQSTVHVVLPP-----STSAHRSELIQQRRLGSGMES--LTRLDLSSSRQTTASEGLAVILETEASRREDTAGHTGAKAHS-SFYVFCKTVCKAIQPGKLRVRCKDCKQGTLTLSRGPSCWDDVLLPNRIHGVCQSQGCNGRL--------AEFYLKCASHPTC-DNDTSVALDLIMPNTRRVPCIACTDIMTPVLVFQCAERHVICLECFHLYCVSRLNERQFTQEPLLGYSLPCAAGCPDSLIKEVHHFHVLGEEQYERYQRYAAEECVLQMGGVLCPAPGCGAGLLPPDEERRVCCEPGNNELGCGFVFCRDCKEEFHEGPCRHTTSTASAGALQGYVVDEEAALRARWEQASQETITKTTHPCPKCQVPVEKNGGCMHMVCPRPQCKFEWCWLCRVEWNRDCMGNHWFE-", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q7KTX7-1", "uniprot_id": "PRKN_DROME", "id": "Q7KTX7-1", "name": "E3 ubiquitin-protein ligase parkin", "aln": "MSFIFKFIATFVRKMLELLQFGGKTLTHTLSIYVKTNTGKTLTVNLEPQWDIKNVKELVAPQLGLQPDDLKIIFAGKELSDATTIEQCDLGQQSVLHAIRLR-----------PPVQRQKIQSATLEEEEPSLSDEAS--KPLNETLLDLQLESEERLNITDEERVRAKAHF---FVHCS-QCDKLCNGKLRVRCALCKGGAFTVHRDPECWDDVLKSRRIPGHCESLEVACVDNAAGDPPFAEFFFKCAEHVSGGEKDFAAPLNLIKNNIKNVPCLACTDVSDTVLVFPCASQHVTCIDCFRHYCRSRLGERQFMPHPDFGYTLPCPAGCEHSFIEEIHHFKLLTREEYDRYQRFATEEYVLQAGGVLCPQPGCGMGLLVEPDCRKVTCQ-----NGCGYVFCRNCLQGYHIGECLPEGTGASATNSCEYTVDPNRAAEARWDEASNVTIKVSTKPCPKCRTPTERDGGCMHMVCTRAGCGFEWCWVCQTEWTRDCMGAHWFG-", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : ::*: *:. :.*::: .: ::** *. *: .*:*::****:** : *:: *** :** :* : :. .. * : * :* . . * : *.:: :. ::.*. *. : *****:* *: .::*: :.*.****** ..*: * *:* ***::**. * : ::: :..*.** * : :.*::***: .**** * :** *::**: ** :**.:*** .. :**:*** *** .*:*:*:***::* .*:* ***::.:** *** ****** **** *** ::* *: ***:.***:* : :* * * .*. * ** . * .***: **: **. :*:***:*..* *::****** *.:. * :**** * **.* *** *** ", "identical_positions": 170, "similar_positions": 129, "identity": "33.66%" }, { "cls_id": "homologset.agr.MGI:1355297", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P58750-1", "uniprot_id": "PIM3_MOUSE", "id": "P58750-1", "name": "Serine/threonine-protein kinase pim-3", "aln": "MLLSKFGSLAHLCGPGGVDHLPVKI-LQPAKADKESFEKVYQVGAVLGSGGFGTVYAGSRIADGLPVAVKHVVKERVTEWGSLGGVAVPLEVVLLRKVGAAGGARGVIRLLDWFERPDGFLLVLERPEPAQDLFDFITERGALDEPLARRFFAQVLAAVRHCHNCGVVHRDIKDENLLVDLRSGELKLIDFGSGAVLKDTVYTDFDGTRVYSPPEWIRYHRYHGRSATVWSLGVLLYDMVCGDIPFEQDEEILRGRLFFRRRVSPECQQLIEWCLSLRPSERPSLDQIAAHPWMLGTEGSVPENCDLRLCALDTDDGASTTSSSESL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O70444-1", "uniprot_id": "PIM3_RAT", "id": "O70444-1", "name": "Serine/threonine-protein kinase pim-3", "aln": "MLLSKFGSLAHLCGPGGVDHLPVKI-LQPAKADKESFEKVYQVGAVLGSGGFGTVYAGSRIADGLPVAVKHVVKERVTEWGSLGGMAVPLEVVLLRKVGAAGGARGVIRLLDWFERPDGFLLVLERPEPAQDLFDFITERGALDEPLARRFFAQVLAAVRHCHNCGVVHRDIKDENLLVDLRSGELKLIDFGSGAVLKDTVYTDFDGTRVYSPPEWIRYHRYHGRSATVWSLGVLLYDMVCGDIPFEQDEEILRGRLFFRRRVSPECQQLIEWCLSLRPSERPSLDQIAAHPWMLGTEGSVPENCDLRLCALDTDDGASTTSSSESL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q86V86-1", "uniprot_id": "PIM3_HUMAN", "id": "Q86V86-1", "name": "Serine/threonine-protein kinase pim-3", "aln": "MLLSKFGSLAHLCGPGGVDHLPVKI-LQPAKADKESFEKAYQVGAVLGSGGFGTVYAGSRIADGLPVAVKHVVKERVTEWGSLGGATVPLEVVLLRKVGAAGGARGVIRLLDWFERPDGFLLVLERPEPAQDLFDFITERGALDEPLARRFFAQVLAAVRHCHSCGVVHRDIKDENLLVDLRSGELKLIDFGSGALLKDTVYTDFDGTRVYSPPEWIRYHRYHGRSATVWSLGVLLYDMVCGDIPFEQDEEILRGRLLFRRRVSPECQQLIRWCLSLRPSERPSLDQIAAHPWMLGADGGVPESCDLRLCTLDPDDVASTTSSSESL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "E7FB10-1", "uniprot_id": "E7FB10_DANRE", "id": "E7FB10-1", "name": "Serine/threonine-protein kinase", "aln": "MLLSKFGSFSHICNTTNIDHLPVKIQLQAAKTEREPFEKVYHVGSVLGSGGFGTVYAGTRISDALPVAIKHVAKERVTEWGTINGSLIPLEIVLLKKVGST--FQGVIKLIDWYERPDGWLIIMERPEMVKDLFDYITEKGALDEDTARGFFRQVLEAVRHCYSCGVVHRDIKDENLLVDLRTGDLKLIDFGSGAILKDTVYTDFDGTRVYSPPEWIRYHRYHGRSATVWSLGVLLYDMVCGDIPFEHDEEILRGRLFFRRRVSPVCQQLIKWCLCLRPSDRPTLEQIFEHQWMRTEEN--PKTAESVNITLHT---ISTEAGNESL", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "********::*:*.. .:******* **.**:::*.***.*:**:*************:**:*.****:***.********::.* :***:***:***:: :***:*:**:*****:*:::**** .:****:***:***** ** ** *** *****:.******************:*:**********:***************************************************:*********:******* *****.***.****:**:*:** * ** :. *:..: :*.. ** :..***", "identical_positions": 232, "similar_positions": 64, "identity": "70.95%" }, { "cls_id": "homologset.agr.MGI:1355299", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O14979-1", "uniprot_id": "HNRDL_HUMAN", "id": "O14979-1", "name": "Heterogeneous nuclear ribonucleoprotein D-like", "aln": "MEVPPRLSHVPPPLFPSAPATLASRSLSHWRPRPPRQLAPLLPSLAPSSARQGARRAQRHVTAQQPSRLAGGAAIKGGRRRRPDLFRRHFKSSSIQRSAAAAAATRTARQHPPADSSVTMEDMNEYSNIEEFAEGSKINASKNQQDDGKMFIGGLSWDTSKKDLTEYLSRFG-------------EVVDCTIKTDPVTG----RSRGFGFVLFKDAASVDKVLELKEHKLDGKLIDPKRAKALKGKE------------PPKKVFVGGLSPDTSEEQIKEYFGAFGEIENIELPMDTKTNERRGFCFITYTDEEPVKKLLESR-YHQIGSGKCEIKVAQPKEVYRQQQQQQKGGRGAAAGGRGGTRGRGRGQGQNWN-QGFNNYYDQGYGNYNSAYGGDQNYSG--YGGYDY--TGYNYG----NYGYG--------------QGYADYSGQQSTYGKASRGGGNHQNNYQPY", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9Z130-1", "uniprot_id": "HNRDL_MOUSE", "id": "Q9Z130-1", "name": "Heterogeneous nuclear ribonucleoprotein D-like", "aln": "-----------------------------------------------------------------------------------------------------------------------MEDMNEYSNIEEFAEGSKINASKNQQDDGKMFIGGLSWDTSKKDLTEYLSRFG-------------EVVDCTIKTDPVTG----RSRGFGFVLFKDAASVDKVLELKEHKLDGKLIDPKRAKALKGKE------------PPKKVFVGGLSPDTSEEQIKEYFGAFGEIENIELPMDTKTNERRGFCFITYTDEEPVKKLLESR-YHQIGSGKCEIKVAQPKEVYRQQQQQQKGGRGAAAGGRGGARGRGRGQGQNWN-QGFNNYYDQGYGNYNSAYGGDQNYSG--YGGYDY--TGYNYG----NYGYG--------------QGYADYSGQQSTYGKASRGGGNHQNNYQPY", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q3SWU3-1", "uniprot_id": "HNRDL_RAT", "id": "Q3SWU3-1", "name": "Heterogeneous nuclear ribonucleoprotein D-like", "aln": "-------------------------------------------------------------------------------------------MTGTARSALPLPQSPARALRPSG-----AARAAPSLSPSRFS-ACPLDPSSFPTSGNKMFIGGLSWDTSKKDLTEYLSRFG-------------EVVDCTIKTDPVTG----RSRGFGFVLFKDAASVDKVLELKEHKLDGKLIDPKRAKALKGKE------------PPKKVFVGGLSPDTSEEQIKEYFGAFGEIENIELPMDTKTNERRGFCFITYTDEEPVKKLLESR-YHQIGSGKCEIKVAQPKEVYRQQQQQQKGGRGAAAGGRGGARGRGRGQGQNWN-QGFNNYYDQGYGNYNSAYG-DESYSG--YGGYDY--TGYNYG----SYGYG--------------QGYTDYSGQQSTYGKASRGGGNHQNNYQPY", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q08473-1", "uniprot_id": "SQD_DROME", "id": "Q08473-1", "name": "RNA-binding protein squid", "aln": "-------------------------------------------------------------------------------------------MAENKQVDTEINGEDFTKDVTADGPGSENGDAGAAGSTNGSS-DNQSAASGQRDDDRKLFVGGLSWETTEKELRDHFGKYG-------------EIESINVKTDPQTG----RSRGFAFIVFTNTEAIDKVSAADEHIINSKKVDPKKAKARHG-----------------KIFVGGLTTEISDEEIKTYFGQFGNIVEVEMPFDKQKSQRKGFCFITFDSEQVVTDLLKTP-KQKIAGKEVDVKRATPKPENQMMGGMRGGPRGGMRGGRGGYGGRG-GYNNQWDGQGSYGGYGGGYGGYG-AGGYGDYYAGGYYNGYDYGYDGYGYGGGFEGNGYGGGGGGNMGGGRGGPRGGGGPKGGGGFNGGKQRGGGGRQQRHQPY", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P53883-1", "uniprot_id": "NOP13_YEAST", "id": "P53883-1", "name": "Nucleolar protein 13", "aln": "-----------------------MSETELSKEDAVTKKDNEEQVKKALLDPTKKRKAEDEIEIDLKSSIPLSKKQKRLLRRGKVTLEELNAKYNIDPKSIEEYKEDAEKKKSGASEKDAQGEESTINTPTGDESGEVVKKKKKDENKYGVWIGNLSFDTTKDDLVRFFIAKTKDNEDEKSRVTEQDITRLSMPRVAAKNSNAMKNKGFCYMFFKNVEQMKAVLELSESHLNGRNMLIKDSENYSGRPDKDDLVAMSKNPPSRILFVGNLSFDVTDDLLRKHFQHCGDIVKIRMATFEDSGKCKGFAFIDFKNEEGSTNALKDKSCRKIAGRPLRMEYGEDRSKRQVRKKVENVSRNNSS---SFDISNNKGYDRAGQDNGSKPEYKRSNANRRPPVDSNNRTKS----------------------------------------SVALATAQRGSAAIVPSQGKKVKFD----", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . . . :::*.**::*::.:* .: :: .: . .. :.:** ::.*.:. :. * .* ::.: : * :: * :***.*: : ::: :: :* *:* ::.:. ...: :**.** : .*: .. *: ::*.. :: . : : . *. . ... * .. : :* * . .. . . .: . . .. . . * : ", "identical_positions": 31, "similar_positions": 102, "identity": "6.55%" }, { "cls_id": "homologset.agr.MGI:1355303", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q32KJ6-1", "uniprot_id": "GALNS_RAT", "id": "Q32KJ6-1", "name": "N-acetylgalactosamine-6-sulfatase", "aln": "MTACSTAIRAQQLLLPVLSALGLLAAGAPQPPNIVLLLMDDMGWGDLGVYGEPSRETPNLDRMAAEGMLFPSFYSANPLCSPSRAALLTGRLPIRNGFYTTNAHARNAYTPQEIMGGIPNSEHLLPELLKKAGYTNKIVGKWHLGHRPQFHPLKHGFDEWFGSPNCHFGPYDNKVKPNIPVYRDWEMVGRFYEEFPINLKTGEANLTQLYLQEALDFIRTQHARQSPFFLYWAIDATHAPVYASKQFLGTSLRGRYGDAVREIDDSVGKILSLLQNLGISKNTFVFFTSDNGAALISAPKEGGSNGPFLCGKQTTFEGGMREPAIAWWPGHIAAGQVSHQLGSIMDLFTTSLSLAGLKPPSDRVIDGLDLLPTMLQGHIIDRPIFYYRGNTLMAVTLGQYKAHLWTWTNSWEEFRQGIDFCPGQNVSGVTTHTQEEHTELPLIFHLGRDPGERFPLRFTSNEYQDALSRTTQVIQQHQKSLVPGQPQLNVCNQAVMNWAPPGCEKLGKCLTPPESVPEKCFWAH", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q571E4-1", "uniprot_id": "GALNS_MOUSE", "id": "Q571E4-1", "name": "N-acetylgalactosamine-6-sulfatase", "aln": "MAACT----AAQQLLLVLSALGLLAAGAPQPPNIVLLLMDDMGWGDLGVNGEPSRETPNLDRMAAEGMLFPSFYSANPLCSPSRAALLTGRLPIRNGFYTTNAHARNAYTPQEIMGGIPNSEHLLPELLKKAGYTNKIVGKWHLGHRPQFHPLKHGFDEWFGSPNCHFGPYDNKAKPNIPVYRDWEMVGRFYEEFPINRKTGEANLTQLYTQEALDFIQTQHARQSPFFLYWAIDATHAPVYASRQFLGTSLRGRYGDAVREIDDSVGKILSLLQNLGISKNTFVFFTSDNGAALISAPNEGGSNGPFLCGKQTTFEGGMREPAIAWWPGHIAAGQVSHQLGSIMDLFTTSLSLAGLKPPSDRVIDGLDLLPTMLKGQMMDRPIFYYRGNTLMAVTLGQYKAHLWTWTNSWEEFTQGTDFCPGQNVSGVTTHTQEEHTELPLIFHLGRDPGERFPLSFHSDEYQDALSRTTQVVQEHQKSLVPGQPQLNVCNQAVMNWAPPGCEKLGKCLTPPESVPEKCFWAH", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P34059-1", "uniprot_id": "GALNS_HUMAN", "id": "P34059-1", "name": "N-acetylgalactosamine-6-sulfatase", "aln": "MAAVVAAT-RWWQLLLVLSAAGMGASGAPQPPNILLLLMDDMGWGDLGVYGEPSRETPNLDRMAAEGLLFPNFYSANPLCSPSRAALLTGRLPIRNGFYTTNAHARNAYTPQEIVGGIPDSEQLLPELLKKAGYVSKIVGKWHLGHRPQFHPLKHGFDEWFGSPNCHFGPYDNKARPNIPVYRDWEMVGRYYEEFPINLKTGEANLTQIYLQEALDFIKRQ-ARHHPFFLYWAVDATHAPVYASKPFLGTSQRGRYGDAVREIDDSIGKILELLQDLHVADNTFVFFTSDNGAALISAPEQGGSNGPFLCGKQTTFEGGMREPALAWWPGHVTAGQVSHQLGSIMDLFTTSLALAGLTPPSDRAIDGLNLLPTLLQGRLMDRPIFYYRGDTLMAATLGQHKAHFWTWTNSWENFRQGIDFCPGQNVSGVTTHNLEDHTKLPLIFHLGRDPGERFPLSFASAEYQEALSRITSVVQQHQEALVPAQPQLNVCNWAVMNWAPPGCEKLGKCLTPPESIPKKCLWSH", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F8W261-1", "uniprot_id": "F8W261_DANRE", "id": "F8W261-1", "name": "N-acetylgalactosamine-6-sulfatase", "aln": "--------MCLQAVICVLWTVYVCQTSG--SPNIIIMLMDDMGWGDLGVFGEPSKETPYLDLMAAQGMLFPNFYTANPLCSPSRAALLTGRLPVRNGFYTTNAHARNAYTPQEIVGGISADEILLPELLKNKHYVSKIVGKWHLGHRTQYLPLKHGFDEWFGAPNCHFGPYNDSSRPNIPVYNNSEMKGRYYEEFEINVKTGESNLTQLYLKEGLDFISQQAMAQRPFFLYWAPDATHAPVYASKPFLGKSQRGRYGDAVMELDDSIGQILAHLVSLGIQNDTLVFFTSDNGAALMSGPLQSGSNAPFLCGKETTFEGGMREPAMAWWPGQIPAGTVSHQLASVMDLFSTSLSVAGVSPPDDRVIDGVDLSPVLFNGSLIDRPIFYYRGNQMMAVRIGQYKAHYWTWSNSMEEFNKGINFCPGQEVPGVTTHTQQEHTMQPLIFHLGRDPGERYPLSVQCKEYRDVFRRVTAVVEQHQKLLIPGQPQLNMCDLAVMNWTPPGCEQLGKCLKAPESQPWKCDWPH", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :: ** : : :.. .***:::************ ****:*** ** ***:*:***.**:******************:********************:***. .* *******: *..***********.*: ***********:********::. :******.: ** **:**** ** ****:****:* :*.**** * : ******* **********: ***.* ******** *:***:*:** * .* : .:*:***********:*.* :.***.******:***********:*****::.** *****.*:****:***::**:.**.**.***::* *.:::* ::*********: :**. :**:*** ***:** *:* :* :*****:*.*****. ::** *************:** . . **::.: * * *:::**: *:*.*****:*: *****:*****:*****..*** * ** *.*", "identical_positions": 341, "similar_positions": 109, "identity": "65.08%" }, { "cls_id": "homologset.agr.MGI:1355305", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9JMH7-1", "uniprot_id": "NEUR3_MOUSE", "id": "Q9JMH7-1", "name": "Sialidase-3", "aln": "------------------------------MEEVPPYSLSSTLFQQEE---QSGVTYRIPALLYLPPTHTFLAFAEKRTSVRDEDAACLVLRRGLMK--GRSVQWGP-QRLLMEATLPGHRTMNPCPVWEKNTGRVYLFFICVRGHVTERCQIVWGKNAARLCFLCSEDAGCSWGEVKDLTEEVIGSEVKRWATFAVGPGHGIQLHSGRLIIPAYAYYVSRWFLCF----ACSVKPHSLMIYSDDFGVTWHHGKFIEPQVTGECQVAEVAGTAGNPVLYCSARTPSRFRAEAFSTDSGGCFQKPTLNPQLHEPRTGCQGSVVSFRPLKMPNTYQDSIGKGAPATQKCPLLDSPLEVEKGAETPSATWLLYSHPTSKRKRINLGIYYNRNPLEVNCWSRP--WILNRGPSGYSDLAVVEEQDLVACLFECGEKNEYERIDFCLFSDHEVLS--CEDCTSPSSD-------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q99PW5-1", "uniprot_id": "NEUR3_RAT", "id": "Q99PW5-1", "name": "Sialidase-3", "aln": "------------------------------MEEVSSCSLRSTLFQQEE---QNRITYRIPALLYIPPTHTFLAFAEMRTSSRDEDAVYLVFRRGVMK--GCSVEWGP-QQPLMEATLPGHRTMSPCPVWEKNTGRVYLFFICVQGHVSERWQLLWGRNAARLCFLYSEDSGCSWGEVKDLTEEVVGSEMKHWATFAVGPGHGIQLQSGRLLIPAYAYLISCWFLCF----PCSVKPHSLMFYSDDLGVTWHCGKFIKPQVTGECQVAEVPGKAGNLVLYCSARTPNKFRAEAFSTDSGDCFQKPTLNQQLCEPRGGCQGSVVSTRPLKMPYTCQDSSGKDVPSTQKCPLMDRSLEVEEGAGAPSGTWLLYSHPTNKKKRMNLGIYYNQNPLEVNYWSRP--WILNRGPSGYSDLAVVEGQGLFACLFECGERHEDEKIDFCLFSDQEVLS--CDDCTSPSSN-------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9UQ49-1", "uniprot_id": "NEUR3_HUMAN", "id": "Q9UQ49-1", "name": "Sialidase-3", "aln": "------------------------------MEEVTTCSFNSPLFRQED---DRGITYRIPALLYIPPTHTFLAFAEKRSTRRDEDALHLVLRRGLRI--GQLVQWGP-LKPLMEATLPGHRTMNPCPVWEQKSGCVFLFFICVRGHVTERQQIVSGRNAARLCFIYSQDAGCSWSEVRDLTEEVIGSELKHWATFAVGPGHGIQLQSGRLVIPAYTYYIPSWFFCFQL--PCKTRPHSLMIYSDDLGVTWHHGRLIRPMVTVECEVAEVTGRAGHPVLYCSARTPNRCRAEALSTDHGEGFQRLALSRQLCEPPHGCQGSVVSFRPLEIPHRCQDSSSKDAPTIQQS-SPGSSLRLEEEAGTPSESWLLYSHPTSRKQRVDLGIYLNQTPLEAACWSRP--WILHCGPCGYSDLAALEEEGLFGCLFECGTKQECEQIAFRLFTHREILSHLQGDCTSPGRNPSQFKSN", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AC58IA72-1", "uniprot_id": "A0AC58IA72_DANRE", "id": "A0AC58IA72-1", "name": "exo-alpha-sialidase", "aln": "MCDISVYMPHVTDTLIIYSVNRVKSMMMAYSSSHSAPPEISILFKQEPPLGKKQVTYRIPALIYISDKQTFLAFAEKRKTPSDTDADVLVMRKGLWKNDNQ-VEWVSDQQVFTSACLPNHRSMNPCPVYERESKTLFLFFICVPLGVSERKQIKEDKNQARLCYITSKDTGETWSAVSDLTADVIGEQEKNWATFAVGPGHGVQMKSGRLIIPAYAYRYTDKPVCILCCCLSFCTPYALAFYSDDQGITWKAGQQMD-VESCECQMAEIVGEKGDSTLYCNARTRLGYRTEALSNNAGEDFDTVLSSNKLIETGKGCQGSVLSFLE---------------------------------QSSPPQTWLLYSHPSNPKKRVDLGLYLNKSPLDSSGWSDEPLMILHHGPSAYSDLVEFEPG-HFACLMECGKEYENEEIAFLLFKLPEKKL-------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A0R4IGG5-1", "uniprot_id": "A0A0R4IGG5_DANRE", "id": "A0A0R4IGG5-1", "name": "exo-alpha-sialidase", "aln": "MMGCCCLS--------------------RHSSSYSAPPEISILFKQELPQCKKQVTYRIPALIYISDKQTFLAFAERRKTPSDTDAELLVMKKGLWKNDNNPVKWVSGQQVFTSACLPNHRSMNPCPVYERKSKTLFLFFICVPVGVSEQQQKNEKKNQARLCYITSKDTGETWSAVTDLTADVIGEQEKNWATFAVGPGHGIQMKSGRLIIPAYTYFFTSE---------NPPTSHAFAIYSDDKGSTWHIGKCMNGLPSNECQMAEIIDDEGNSKLYCNARSTIHYRVQALSESKGTDFDTSSSVNKLIETGNGCQGSVLSFTP---------------------------------DQASEKTWLLYCHPTNATNRLTLGVYLNKCASDLSGWGNP--VILHEGPSGYSDLTQCGDGKHFACLMECGEKSELEGIGFILFEQKDDKAEKLQITKFTKQN-------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0AC58IA66-1", "uniprot_id": "A0AC58IA66_DANRE", "id": "A0AC58IA66-1", "name": "exo-alpha-sialidase", "aln": "MLFTYVYVYLG---------MIDNMASKSYPEAQRPPPARTVLFQQ-----KDGKTYRIPALIYISDGQTFLAFAEERSTPRDSDAKVLVMRKGSLHNGSL--QWTS-AQTLTSACLPDHRTMNPCPVYERKSKTIYLFFICISGNTTEYHQIAMGRNRARLCYITSADYGETWSELTDLTNSVIGDEIHNWATFAVGPGHGIQMKSGRLIIPAYVYYVHCR--CFPFNFPLIVRPHALSFYSDDCGVTWQMGGKIQ-MKSCECEMAEIIDHADQSHLYCNARSTCGYRIEALSETSGAAFDNPHVARKLVEPRHGCQGSVLSFPVPQPLDEEEKKA------------------TDCLTQSDSKTWLLYSHPTNKKKRKDLGVYLNKSPLNASGWSRP--WIIYKGPSGYSDLTQCEER--FGCLMECGEKSEIEGIAFVEFKLNDLLCS------------------", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . . . : **:* . *******:*:. :******* *.: * ** **:::* . :* . : : .* **.**:*.****:*::: ::*****: .:* * :* ****:: * * * :*. : *** .*:*.: :.***********:*::****:****.* .::: :**** * **: * : : **::**: . .. ***.**: * :*:* * *: :* *. ******:* : :****.**:. :* **:* *: . : *. *: **..****. ..**:*** . * * * * * : ", "identical_positions": 139, "similar_positions": 92, "identity": "29.64%" }, { "cls_id": "homologset.agr.MGI:1355307", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "G3V6X6-1", "uniprot_id": "G3V6X6_RAT", "id": "G3V6X6-1", "name": "", "aln": "MSVLRKSMSFSLMGTLAASCLLLVALWAQKADALPINSQCKLEAANFQQPYIVNRTFMLAKEASLADNNTDVRLIGEELFRGVKAKDQCYLMKQVLNFTLEDVLLPQSDRFQPYMQEVVPFLTKLSSHLSPCHISGDDQNIQKNVRQLKETVQKLGESGEIKAIGELDLLFMSLRNACV", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9JJY9-1", "uniprot_id": "IL22_MOUSE", "id": "Q9JJY9-1", "name": "Interleukin-22", "aln": "MAVLQKSMSFSLMGTLAASCLLLIALWAQEANALPVNTRCKLEVSNFQQPYIVNRTFMLAKEASLADNNTDVRLIGEKLFRGVSAKDQCYLMKQVLNFTLEDVLLPQSDRFQPYMQEVVPFLTKLSNQLSSCHISGDDQNIQKNVRRLKETVKKLGESGEIKAIGELDLLFMSLRNACV", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9GZX6-1", "uniprot_id": "IL22_HUMAN", "id": "Q9GZX6-1", "name": "Interleukin-22", "aln": "MAALQKSVSSFLMGTLATSCLLLLALLVQGGAAAPISSHCRLDKSNFQQPYITNRTFMLAKEASLADNNTDVRLIGEKLFHGVSMSERCYLMKQVLNFTLEEVLFPQSDRFQPYMQEVVPFLARLSNRLSTCHIEGDDLHIQRNVQKLKDTVKKLGESGEIKAIGELDLLFMSLRNACI", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*:.*:**:* ******:*****:** .* . * *:.::*:*: :*******.************************:**:**. .::*************:**:*****************::**.:**.***.*** :**:**::**:**:*************************:", "identical_positions": 133, "similar_positions": 37, "identity": "74.3%" }, { "cls_id": "homologset.agr.MGI:1355310", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9JLI6-1", "uniprot_id": "SCLY_MOUSE", "id": "Q9JLI6-1", "name": "Selenocysteine lyase", "aln": "MDAARN---GALGSVESLP---------DRKVYMDYNATTPLEPEVIQAVTEAMKEAWGNPSSSYVSGRKAKDIINAARASLAKMIGGKPQDIIFTSGGTESNNLVIHSMVRCFHEQQTLKGNMVDQHSPEEGTRPHFITCTVEHDSIRLPLEHLVENQMAEVTFVPVSKVNGQAEVEDILAAVRPTTCLVTIMLANNETGVIMPVSEISRRIKALNQIRAASGLPRVLVHTDAAQALGKRRVDVEDLGVDFLTIVGHKFYGPRIGALYVRGVGKLTPLYPMLFGGGQERNFRPGTENTPMIAGLGKAADLVSENCETYEAHMRDIRDYLEERLEAEFG-KRIHLNSRFPGVERLPNTCNFSIQGSQLQGYTVLAQCRTLLASVGASCHSNHEDRPSPVLLSCGIPVDVARNAVRLSVGRGTTRADVDLIVQDLKQAVAQLEGRL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q68FT9-1", "uniprot_id": "SCLY_RAT", "id": "Q68FT9-1", "name": "Selenocysteine lyase", "aln": "MDVARN---GARGSVESPP---------NRKVYMDYNATTPLEPEVIQAVTEAMKEAWGNPSSSYVAGRKAKDIINTARASLAKMIGGKPQDIIFTSGGTESNNLVIHSTVRCFHEQQTLQGRTVDQISPEEGTRPHFITCTVEHDSIRLPLEHLVEDQVAEVTFVPVSKVNGQVEVEDILAAVRPTTCLVTIMLANNETGVIMPISEISRRIKALNQIRAASGLPRVLVHTDAAQALGKRRVDVEDLGVDFLTIVGHKFYGPRIGALYVRGVGKLTPLYPMLFGGGQERNFRPGTENTPMIAGLGKAADLVSENCETYEAHMRDIRDYLEERLEAEFG-KRIHLNSRFPGVERLPNTCNFSIQGSQLRGYMVLAQCQTLLASVGASCHSDHEDRPSPVLLSCGIPVDVARNAVRLSVGRSTTRAEVDLIVQDLKQAVNQLEGPV", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q96I15-1", "uniprot_id": "SCLY_HUMAN", "id": "Q96I15-1", "name": "Selenocysteine lyase", "aln": "MEAAVAPGRDAPAPAASQPSGCGKHNSPERKVYMDYNATTPLEPEVIQAMTKAMWEAWGNPSSPYSAGRKAKDIINAARESLAKMIGGKPQDIIFTSGGTESNNLVIHSVVKHFHANQTSKGHTGGHHSPVKGAKPHFITSSVEHDSIRLPLEHLVEEQVAAVTFVPVSKVSGQAEVDDILAAVRPTTRLVTIMLANNETGIVMPVPEISQRIKALNQERVAAGLPPILVHTDAAQALGKQRVDVEDLGVDFLTIVGHKFYGPRIGALYIRGLGEFTPLYPMLFGGGQERNFRPGTENTPMIAGLGKAAELVTQNCEAYEAHMRDVRDYLEERLEAEFGQKRIHLNSQFPGTQRLPNTCNFSIRGPRLQGHVVLAQCRVLMASVGAACHSDHGDQPSPVLLSYGVPFDVARNALRLSVGRSTTRAEVDLVVQDLKQAVAQLEDQA", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*:.* .* ... * * :********************:*:** ********.* :*********:** ***************************** *: ** :** :*. .: ** :*::*****.:***************:*:* *********.**.**:********** ************::**:.***:******* *.*:*** :************:****************************:**:*::*********************************:**::***:*******:************* *******:***.:**********:*.:*:*: *****:.*:*****:***:* *:******* *:*.******:******.****:***:******** ***. ", "identical_positions": 339, "similar_positions": 67, "identity": "76.18%" }, { "cls_id": "homologset.agr.MGI:1355311", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O70576-1", "uniprot_id": "STAG3_MOUSE", "id": "O70576-1", "name": "Cohesin subunit SA-3", "aln": "MPTLWSPSTQHHGSSSGSESSPLQKSVRRAQMALSPCSSS---ILPCDDRDSQGTAEWD--SPSTNEDSDFEDSLRRNVKKRAAKQPPKAVPAAKHRKKQSRIVSSGNGKNESV------------------PSTNYLFDAVKAARSCMQSLVDEWLDNYKQDENAGFLELINFFIRACGCKSTVTPEMFKTMSNSE----IIQHLTEEFNEDSGDYPLTAPGPSWKKFQG-----SFCEFVKTLVYQC------------QYSLLYDGFPMDDLISLLIGLSDSQVRAFRHTSTLAAMKLMTSLVKVALQLSLHKDNNQRQYEAERNKGPEQRAPERLESLLEKRKEFQENQEDIEGMMNAIFRGVFVHRYRDILPEIRAICIEEIGYWMQSYSTSFLNDSYLKYIGWTLHDKHKEVRLKCVKALAGLYSNQE-----LSLRMELFTNRFKDRMVSMVMDRECEVAVEAIRLLTLILKNMEGVLTSADCEKIYSIVYISNRAMASSAGEFVYWKIFHPECGAKAVSDRERRRSPQAQKTFIYLLLAFFMESEHHNHAAYLVDSLWDCAGSYLKDWESLTNLLLQK----DQNLGDMQERMLIEILVSSARQAAEGHPPVGRITGKKS-LTAKERKLQAYDKMKLAEHLIPLLPQLLAKFSADAENVAPLLQLLSYFDLSIYCTQRLEKHLELLLQQLQEVVVKHVEP-EVLEAAAHALYLLCKPEFTFFSRVDFARSQLVDFLTDRFQQELDD---LMQSS-FLDEDEVYSLTATLKRLSAFYNAHDLTRWEISEPCSRLLRKAVDTG------EVPHQVILPALTLVYFSILWTVTHISES--TSHKQ---LMSLKKRMVAFCELCQSCLSD-VDPEIQEQAFVLLSDLLLIFSPQMIVGGRDFLRPLVFFPEATLQSELASFLMDHVFLQPGELGNGQSQEDHVQIELLHQRRRLLAGFCKLLLYGVLELDAASDVFKHYN-KFYEDYGDIIKETLTRARQIDRCQCSRILLLSLKQLYTELIQEQGPQGLTELP----AFIEMRDLARRFALSFGPQQLHNRDLVVMLHKEGIKFSLSELPPAGSSHEPPNLAFLELLSEFSPRLFHQDKRLLLSYLEKCLQRVSKAP-NHPWGPVTTYCHSLHPLEITAEASPRGPPHSKKRCVEGPCRP-QEEESSSQEESLQLNSGPTTPTLTSTAVKRKQSLRTVGKKQKGRPGPGPGPGP----------------ELICSQQLLGTQRLKMSSAPCFQIRCDPSGSGLGKQLTRLSLMEEDEEEELRLLD---EEWQRGDKMLHSPSSPSEHGLDLLDTTELNMEDF", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q99M76-1", "uniprot_id": "STAG3_RAT", "id": "Q99M76-1", "name": "Cohesin subunit SA-3", "aln": "MPTLWSPSTQHHGSSSGSMSSPLRKSVRCAQMALSPCSSN---IQPCDDRDSQGTAEWD--SSSTSEDSDFEDSLRRNVRKRAAKRPPKAIPVAKHPKKQSHIVPGGNDKNKSV------------------PPTSDLFDAVKAARSCAQSLVDEWLENYKQDENAGFLELVNFFIRACGCKSTVTPEMFKTMSNSE----IIQHLTEEFNEDSGDYPLTAPGPSWKKFQG-----SFCEFVKTLVCQC------------QYSLLFDGFPMDDLISLLIGLSDSQVRAFRHTSTLAAMKLMTSLVKVALQLSLHKDNNQRQYEAERNKGPEQRAPERLESLLEKRKEFQENQEEIEGMMNAIFRGVFVHRYRDILPEIRAVCIEEIGCWMQSYSTSFLNDSYLKYIGWTLHDKHKEVRLKCVKALAGLYSNQE-----LSSRMELFTNRFKDRMVSMVMDRESEVAVEAIRLLTLILKNMEGVLTSADCEKIYSIVYISNRAMASSAGEFVYWKIFHPECGAKAVSGRERRRSPQAQRTFIYLLLAFFMESEHHDHAAYLVDSLWDCAGSYLKDWESLTSLLLQK----DQNLGDMQERMLIEILVSSARQAAEGHPPVGRITGKKS-LTAKERKLQAYDKVKLAEHLIPLLPQLLAKFSADAENVAPLLRLLSYFDLNIYCTQRLEKHLELLLQQLQEVVVKHVEP-EVLEAAAHALYLLCKPEFTFFSRVDFARSQLVDLLTDRFQQELDD---LMQSS-FLDEDEVYSLTATLKRLSAFYNAHDLTRWEISEPCSRLLRKAVDTG------EVPHQVILPALTLVYFSILWTVTHISES--TSQKQ---LMSLKKRMVAFCELCQSCLSD-VDPEIQEQAFVLLSDLLLIFSPQMVVGGRDFLRPLVFFPEATLQSELASFLMDHVFLQPGELGNGQSQEDHVQIELLHQRRRLLAGFCKLLLYGVLELDAASDVFKHYN-KFYEDYGDIIKETLTRARQIDRCQCSRILLLSLKQLYTELIQEQGPQDLTELP----AFIEMRDLARRFALSFGPQQLHNRDLVVMLHKEGIKFSLSELPPAGSSREPPNIAFLELLSEFSPRLFHQDKQLLLSYLEKCLQRVSMAP-SHPWGPVTTYCHSLHLVENTAEASSQGPPHSKKRCIEVPRRL-QEEESSSQGESLQLNSGPTTPTLTSTAVKRRQSPRTVGKRQKGGPGPGPGPGPGPGPGPGPGPGPGPGPELICSQQLSGTQRLKMSSAPCFQIRCDPSGSGLGKQMTRLSLMEEDEEEELRLLD---EEWQCGDKLLHSPSSPSEHGLDLLDTTELNMEDF", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9UJ98-1", "uniprot_id": "STAG3_HUMAN", "id": "Q9UJ98-1", "name": "Cohesin subunit SA-3", "aln": "------------------MSSPLQRAVGDTKRALSASSSSSA-SLPFDDRDSNHTSEGNGDSLLADEDTDFEDSLNRNVKKRAAKRPPKTTPVAKHPKKGSRVVHR-HSRKQSE------------------PPANDLFNAVKAAKSDMQSLVDEWLDSYKQDQDAGFLELVNFFIQSCGCKGIVTPEMFKKMSNSE----IIQHLTEQFNEDSGDYPLIAPGPSWKKFQG-----SFCEFVRTLVCQC------------QYSLLYDGFPMDDLISLLTGLSDSQVRAFRHTSTLAAMKLMTSLVKVALQLSVHQDNNQRQYEAERNKGPGQRAPERLESLLEKRKELQEHQEEIEGMMNALFRGVFVHRYRDVLPEIRAICIEEIGCWMQSYSTSFLTDSYLKYIGWTLHDKHREVRLKCVKALKGLYGNRD-----LTTRLELFTSRFKDRMVSMVMDREYDVAVEAVRLLILILKNMEGVLTDADCESVYPVVYASHRGLASAAGEFLYWKLFYPECEIRMMGGREQRQSPGAQRTFFQLLLSFFVESELHDHAAYLVDSLWDCAGARLKDWEGLTSLLLEK----DQNLGDVQESTLIEILVSSARQASEGHPPVGRVTGRKG-LTSKERKTQADDRVKLTEHLIPLLPQLLAKFSADAEKVTPLLQLLSCFDLHIYCTGRLEKHLELFLQQLQEVVVKHAEP-AVLEAGAHALYLLCNPEFTFFSRADFARSQLVDLLTDRFQQELEE---LLQSS-FLDEDEVYNLAATLKRLSAFYNTHDLTRWELYEPCCQLLQKAVDTG------EVPHQVILPALTLVYFSILWTLTHISKSD-ASQKQ---LSSLRDRMVAFCELCQSCLSD-VDTEIQEQAFVLLSDLLLIFSPQMIVGGRDFLRPLVFFPEATLQSELASFLMDHVFIQPGDLGSGDSQEDHLQIERLHQRRRLLAGFCKLLLYGVLEMDAASDVFKHYN-KFYNDYGDIIKETLTRARQIDRSHCSRILLLSLKQLYTELLQEHGPQGLNELP----AFIEMRDLARRFALSFGPQQLQNRDLVVMLHKEGIQFSLSELPPAGSSNQPPNLAFLELLSEFSPRLFHQDKQLLLSYLEKCLQHVSQAP-GHPWGPVTTYCHSLSPVENTAETSPQVLPSSKRRRVEGPAKPNREDVSSSQEESLQLNSIPPTPTLTSTAVKSRQPLWGLKEMEEEDGSE---------------------LDFAQGQPVAGTERSRFLGPQYFQTPHNPSGPGLGNQLMRLSLMEEDEEEELEIQDESNEERQDTDMQASSYSSTSERGLDLLDSTELDIEDF", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VM62-1", "uniprot_id": "Q9VM62_DROME", "id": "Q9VM62-1", "name": "", "aln": "-------MMARRGGKRIRMDDPPPDYEELHSDALNESTSDADSPTKRMTRLRARGGVRDKPPIIDDDEDDFFAPIARKRKTPATRKGPTERKERVERPRKEPVDKGHHERIDSEREIT--------------TDENSLYYIVRHSKNPIASIVDQWIEQYKANRETALVALMQFFINASGCKGKISEDIQYPVDHTS----IIRRMTEEFDEESGEYPLIMSGTQWRKFKN-----NFCDFVQTLVKQC------------QYSIIYDQFLMDNVISLLTGLSDSQVRAFRHTATLAAMKLMTALVDVALLVSNNFDNAAKQFEAERVKSRDRRASDRLDSLMTKRSELEENMDEIKSMLTYMFKSVFVHRYRDSLPDIRAICMAEIGIWMENYPQNFLDDSYLKYIGWTLHDKIGEVRLRCLQSLLPLYEKDE-----LKGKLELFTSKFKDRIVAMTLDKEFEVSVHAVKLVISILKIHPEILADKDCEIVYELVYSSHRGVAQAAAEFLNVRLFHLTADMEETKTK-RGKVRMPNTPLVRDLVQFFIESELHEHGAYLVDSFIDSN-DMVRDWECMTDLLLEEPGPNEEVLDNKQESTLIEIMVSSVKQSATGEVPVGRASNRKCTLSAKELKAIQDEKAKLTEHFIVTLPSLLEKYQADSEKLANLLAVPQYFDLNLYTTNRQEGNLQALLDRINQVMSMHTGR-EVLETCAKTLECLCAEGSATYTRCNIARSNIIESAVNKYKDAIEEWRNLIQGEETPNEDDIYNITITLKVLSILYSSHNLNPWELFKSLFQDVEEAQSKENIDR--CLPNEALVYCIEACYFSISWGLQYVENEC-ESVNVTEVVAELRNNLDTFMGACFELTRDGPTVQIQEAAYQSICDLLIIFSDKLARSEIEHIRGLEYKSRMDEHLILDNFVQHYVFSLKQDVAQDETR-----IEELHKKRNFLACYCKLVVYNIIPTMRAASIFKYYV-KCYNDYGDIIKATLGKAREINKVNFAMTLLLSLITVFKSLQEQSEDGIVSKSSQ---EFVDLKELAKRFALTFGFDAIKNRESVAAIHRGGIYFAANKEP-DDPVRAPTRLLFLEVLNEFNYKLLKQDKKVIMSFLDKIIPPAMPSSRAEEWQPLILYRNSLLHGETDQAPVASKRAYTRKR----------RDHDEEEEE------------------------------------------------------------------------------------------------------EEDEEE---------------------HNDPDYRG--------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9W0F4-1", "uniprot_id": "Q9W0F4_DROME", "id": "Q9W0F4-1", "name": "", "aln": "----------------------------------------------------MSDISFDDAVLNDSQASNQMDFEIREECSIAPNDEPVCVDGTVGDATNKSLLQMILSRKRLS--------------------------PTNKRNSHIESVAKYWGEFYLDSPTAALVALLQFVVEVSGSHYQIPDDTSMPFSYSD----ILSNSSSHFSNTHIYPLIRKPADVFVNQVG-----SFLN--ALLLVAN------------KFRSDSYQLFLVQLTNFVMACSESNIRTFRHTATMIGLKIMTILSDLKSLD----------------------------------------DEIAMTVWMQMFNSMFVARSRDIVTDIRLLCISELGQWFARYPHCHLQPTSLRIFYEALNDGSGDVIQCSLDNISVLCRKDV-----LFSEIVALTSEFREILVELCLGKEDAIAEKSVQFLTHFHVLSAEILTDDVCRVLEQLIMAANRGLAQAAADLFILRRNGLDG--------------ETFCQRVKHLLQLFIECG-HEQADYLVDSLIDNC-ELVLDWKSMIAVLLENP--KSRELSDIHCSSLIAILLAGVKQATAGEIPPGRYTKDLK------REPRQGAQERATKCLAPVLPELLRTYANRLQDIERLLELPKYFCFDYYHEQNRMGQLNELVEHFELIIFDQTSSTTVLQITVKTLEFLNRMIPIPLT------KQLLNSAVTNYKMAWHR--TQDTSPSRSTHNESNRLLATLRLLTVLSGHFNLSKWDLTEPLLFSLKMLLRQRRLPNGDDLPPEAFSLYLKACFCCLCWDMENLEGTALNNVDMDEYCDVLHHNLEDYLYVTFSLVGKSNTEPLAYPCFSYTCDLFVLHG-NLCGSSNPSIRSVAHVPSGNELDILEGFLMEHFLELSPSDLMLETN-----SDQLQRIRSILTSYLKVVCLGVVPTMRASKFYEYYV-KYHAPFGDVMRCSMELALQRNPIHFAMTMLHTCLLLYAKVFPDDTRHAAGQRALRPAEFSELMELANRLAKILISNPMEHRECVIALHRSGILFVF-ELAQKQPTEATKKLPFLRVLKVFVPLLLVQDKTRILNFFEPYEQLIIPTCNRNDIAHLKEYRNALRPRKTKSYPQAT----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P40541-1", "uniprot_id": "SCC3_YEAST", "id": "P40541-1", "name": "Cohesin subunit SCC3", "aln": "MTAVRRSTRIRTKSQVIEEDYDDEQNTSAQHVESDKITAKTQHEEEEEQDTGESEESSSEDDYEDQDDDDYVDTATAKRKSRKRKPKSASNTSSKRQKKKPTSAQKSAVSHAPAYHRSKKDQDQYLEIAKDFQPTELFDILSTSEDVSIEELLREWLETYSENRDKFLQEFINLLLNCCGSVARVEDHDVHSNESSNETIGEIQLLFQRQKLHEFYLLISKENKKRKNFKMGPLYQNFAEFMTKLLEVANDLQLLYVESDEDDTQIVTGNLVLDLLTWLSSFSVCKIRCFRYISTLTLYLFQDYLTQQAVNLEKNYLAKLSKQLSLEEK-KKRPNNKTLEKLESTIAETQGSKVVIDSIIDNIVKLCFVHRYKDVSDLIRSESMLHLSIWIKNYPEYFLKVTFLKYFGWLLSDNSVSVRLQVTKILPHLIIQNHNSKSTDNSAIRQVFERFKTKILEVAIR-DVNLDVRIHSIQVLTEASSLGYLDDSEILIISSLMFDEEFDPFKTSSFNKRSKFLSTVAKFLARVIKEKFDEFIKTHEDLPKEVDG-LEVGPVVQVGIFIKILNDSLIYHLKDCAEVDSRTKIRMLTQAAEFLSPYISTHLKTICNLLISDTESNELIQKLQNSAN------NNSDDEDVDDEELDITPLFP---------IDRNSTILYLNVFHGLCAGANNPKIQTKDSVKEIVLPLFYDLLNAASIESADILCPLLESFITFSLDDWISIGYETELKKITDKTIKAFMD-----STIGNSKVDMKYDIFAKFIHHIHHFEKKELQEKFLNQIATLKIHLKKFLQEKMD--PNNSRDDYKDLTCSLYELYINKLTILGRDYPIEVDEELLQLFLNNFVSRIPIMFQDFDDSTAQEINFKMLVLLATWNLEKWREIIEKVRDYENSISKDLRSVWKPIAAIIGRLNTLVISLAATN-----------ETFENINSLFYLKWSACTSLMDIIVAIKIFELKLPADATTWRYSMSEQFPFYLHDNASKVLLKIFLYLESLFAKQVDVQLERVADEDAN--LNDLPETGFFENIETEFLLFTVKLKG-LMKLNILDERFASRVALNKEKLGPLFKKIVDDTIMENPEPNKKNIQKAKSNQTQREKAPLQPNSERETDHANTENNDPDIPMTIDLEPIEESSQNNSELAPIEEHPTVVDAIDNSDEITQD----------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . .: : : . . . .: * : * . : ::::.:. .*. : . . :. : .. . : : .* : *: . : :: . : . * .::* **: :*: : * . : :.. ** * :* ** .: .:. *: *. .* : *: : * * .* . : * : : . ..*: :: : : : : . : * . : :: . .::. : . : :* : ::. : * : * : . : . : : . : .. : : : :* : :* : . : : . : . :. : . . :. . . : : .: :* : : :. . : : : : ..: . . : . : :: . : : : . * .:: * ..:: : : : . : : :: :: . : . : ..: : :. : : :: . * . . : : : . : . .. . ", "identical_positions": 36, "similar_positions": 207, "identity": "2.69%" }, { "cls_id": "homologset.agr.MGI:1355312", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q6P6T1-1", "uniprot_id": "C1S_RAT", "id": "Q6P6T1-1", "name": "Complement C1s subcomponent", "aln": "-----MWCFVFFSLLASFSAEPTMYGEILSPNYPQAYPNEVVKTWDIEVPEGFGIHLYFTHLDMELSENCAYDSVQIISGGIEEERLCGQRTSKSPNSPTVEEFQFPYNRLQVVFTSDFSNEERFTGFAAYYSAVDVNECTDFTDVPCSHFCNNFIGGYFCSCPPEYFLHDDMRTCGVNCSGDVFTALIGEIASPNYPNPYPENSRCEYQIRLQEGFRLVLTIRREDFDVEPADSEGNCHDSLTFAAKNQQFGPYCGNGFPGPLTIKTQSNTLDIVFQTDLTGQNKGWKLRYHGDPIPCPKEISANSIWEPEKAKYVFKDVVKITCVDGFEVVEGNVGSTSFYSTCQSNGQWSNSRLECQPVDCGVPEPIENGKVEDPED-TVFGSVIHYTCEEPYYYMEQEEGGEYHCAANGSWVN---DQLGVELPKCIPVCGVPTEPFKVQQRIFGGYSTKIQSFPWQVYFES-PRGGGALIDEYWVLTAAHVVEGNSDPVMYVGSTLLKIERLRNAQRLITERVIIHPSWKQEDDLNTRTNFDNDIALVQLKDPVKMGPTVAPICLPETSSDYNPSEGDLGLISGWGRTENRTNVIQLRGAKLPITSLEKCQQVKVENPKARSNDYVFTDNMICAG--EKGVDSCEGDSGGAFALPVP--NVKDPKFYVAGLVSWGKKCG---TYGIYTKVKNYVDWILKTMQENSGPKKD", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8CG14-1", "uniprot_id": "CS1A_MOUSE", "id": "Q8CG14-1", "name": "Complement C1s-1 subcomponent", "aln": "-----MWCLVLFSLLASFSAEPTMHGEILSPNYPQAYPNDVVKSWDIEVPEGFGIHLYFTHVDIEPSESCAYDSVQIISGGIEEGRLCGQKTSKSPNSPIIEEFQFPYNKLQVVFTSDFSNEERFTGFAAYYTAIDINECTDFTDVPCSHFCNNFIGGYFCSCPPEYFLHDDMRNCGVNCSGDVFTALIGEISSPNYPNPYPENSRCEYQIQLQEGFQVVVTMQREDFDVEPADSEGNCPDSLTFASKNQQFGPYCGNGFPGPLTIRTQSNTLGIVFQTDLMGQKKGWKLRYHGDPISCAKKITANSTWEPDKAKYVFKDVVKITCVDGFEVVEGHVSSTSYYSTCQSDGQWSNSGLKCQPVYCGIPDPIANGKVEEPEN-SVFGTVVHYTCEEPYYYMEHEEGGEYRCAANGRWVN---DQLGIELPRCIPACGVPTEPFQVHQRIFGGQPAKIENFPWQVFFNH-PRASGALINEYWVLTAAHVLEKISDPLMYVGTMSVRTTLLENAQRLYSKRVFIHPSWKKEDDPNTRTNFDNDIALVQLKDPVKMGPKVSPICLPGTSSEYNVSPGDMGLISGWGSTEKKVFVINLRGAKVPVTSLETCKQVKEENPTVRPEDYVFTDNMICAG--EKGVDSCHGDSGGAFAFQVP--NVTVPKFYVAGLVSWGKRCG---TYGVYTKVKNYVDWILKTMQENSGPRKD", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P09871-1", "uniprot_id": "C1S_HUMAN", "id": "P09871-1", "name": "Complement C1s subcomponent", "aln": "-----MWCIVLFSLLAWVYAEPTMYGEILSPNYPQAYPSEVEKSWDIEVPEGYGIHLYFTHLDIELSENCAYDSVQIISGDTEEGRLCGQRSSNNPHSPIVEEFQVPYNKLQVIFKSDFSNEERFTGFAAYYVATDINECTDFVDVPCSHFCNNFIGGYFCSCPPEYFLHDDMKNCGVNCSGDVFTALIGEIASPNYPKPYPENSRCEYQIRLEKGFQVVVTLRREDFDVEAADSAGNCLDSLVFVAGDRQFGPYCGHGFPGPLNIETKSNALDIIFQTDLTGQKKGWKLRYHGDPMPCPKEDTPNSVWEPAKAKYVFRDVVQITCLDGFEVVEGRVGATSFYSTCQSNGKWSNSKLKCQPVDCGIPESIENGKVEDPES-TLFGSVIRYTCEEPYYYMENGGGGEYHCAGNGSWVN---EVLGPELPKCVPVCGVPREPFEEKQRIIGGSDADIKNFPWQVFFDN-PWAGGALINEYWVLTAAHVVEGNREPTMYVGSTSVQTSRLAKSKMLTPEHVFIHPGWKLLEVPEGRTNFDNDIALVRLKDPVKMGPTVSPICLPGTSSDYNLMDGDLGLISGWGRTEKRDRAVRLKAARLPVAPLRKCKEVKVEKPTADAEAYVFTPNMICAGG-EKGMDSCKGDSGGAFAVQDP--NDK-TKFYAAGLVSWGPQCG---TYGLYTRVKNYVDWIMKTMQENSTPRED", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1NG05-1", "uniprot_id": "A0A8M1NG05_DANRE", "id": "A0A8M1NG05-1", "name": "", "aln": "MSEKMLIFCLLWASVDVCECDLAMFGEVSSPQYPNPYPVDFMQHWKLEVPDGYQIQLTINHLDIKPSPNCCNNFLMVVFNNKVLWKFCGQNFTDR-FHPGEKPILAPGSHLQLFFLSDDSNLKSHTGFTASYKAVAV---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------DCGIPELSELMELSEKDPPTTYLKQISLKCKSEFYQLDKK--GNFTCNAEGNWVSENGEKLTKIFPKCEPVCGINMEDLSAG-RVFGGKPARSGEIPWQLLHKSSPRGSATLISDYWALTAASLVDGNENRNMSWLGGIVNAQDTN-AVFMETEKIIIHPNYKKVDKDGRQSDFNNDIALIKMSAMVPLGPNIRPVCLP-KKTDEAVKEGMMGTVSGFG-VYGRTVSKLLRYGHVHVYSLKSCVSG----------DLPVSDNMFCAGDDVHGIDSCSGDSGGPLFFPMLGDGTEEHRYVVKGIVSWGPICAKTITKGYYTKVQNYLDWIEETMAKNS-----", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : :::: : .: :*.**: **:**:.** :. : *.:***:*: *:* :.*:*:: * .*. : : :: .. ::***. :. * : : * .:**:.* ** ** : .***:* * * : **:*: ::.: : : : . : .*:. :* ::: *:: * .:* **. : * :*:* *.**: * :. *::** : .:***: .. * ...:**.:**.**** ::: : * :. : : .::::***.:* : :::*:*****:::. * :**.: *:*** ..:: * :* :**:* . : *: .:: : .*..* . .: **:*** :*:*** *****.: . . :: . *:**** *. * * **:*:**:*** :** :** ", "identical_positions": 130, "similar_positions": 160, "identity": "18.44%" }, { "cls_id": "homologset.agr.MGI:1355313", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8CG16-1", "uniprot_id": "C1RA_MOUSE", "id": "Q8CG16-1", "name": "Complement C1r-A subcomponent", "aln": "MWLFALLV-TLFYGVEGSIYLPQKLYGEVTSPLYPKPYPSDLETTTVITVPMGYRVKLVFWQFDVEPSEGCFYDYVKISADKQTLGRFCGQLDSPLGNPPGSKEFMSQGNKMLLTFHTDFSNEENGTIMFYKGFLAYYQAVDLDECASQPNSVEEGLQPRCQHLCHNYVGGYFCSCHPGYELQKDGQSCQAECSSELYTEPSGYVSSLEYPQPYPPDLRCNYSIRVERGLTVHLKFLDPFEIDDHQQVHCPYDQLQIYANGKNLGEFCGKQRPPDLDTSSNAVDLLFFTDESGDSRGWKLHYTTETIKCPQPKALDEFTIIQDPQPQYQFRDYFIVTCKQGYQLMEGNQALLSFTAVCQNDGTWHRAMPRCKIKNCGQPQSLSNGDFRYITTKGVTTYEASIQYHCHEPYYKMLTRAGSSESMRGIYTCTAQGIWKNEEEGEKMPRCLPVCGKPVNPVTQKERIIRGQPARPGNFPWQAFTTTHGRGGGALLGDRWILTAAHTIYPKHHNKENDNANPKMLVFLGHTNVEQIKKLGHHPVRRVIIHPDYRQDEPNNFEGDIALLELENSVTLGPELLPICLPDNETFYGQGLMGYVSGFGITEDKLAFDLRFVRLPVADSEACQRWLQTKKDTSPFSQNMFCSGDPAVQQDACQGDSGGVFAVRDRNRDIWVATGIVSWGIGCGEGYGFYTKVLNYVDWIKKEMGDEN", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P00736-1", "uniprot_id": "C1R_HUMAN", "id": "P00736-1", "name": "Complement C1r subcomponent", "aln": "MWLLYLLVPALFCRAGGSIPIPQKLFGEVTSPLFPKPYPNNFETTTVITVPTGYRVKLVFQQFDLEPSEGCFYDYVKISADKKSLGRFCGQLGSPLGNPPGKKEFMSQGNKMLLTFHTDFSNEENGTIMFYKGFLAYYQAVDLDECASRSKSGEEDPQPQCQHLCHNYVGGYFCSCRPGYELQEDTHSCQAECSSELYTEASGYISSLEYPRSYPPDLRCNYSIRVERGLTLHLKFLEPFDIDDHQQVHCPYDQLQIYANGKNIGEFCGKQRPPDLDTSSNAVDLLFFTDESGDSRGWKLRYTTEIIKCPQPKTLDEFTIIQNLQPQYQFRDYFIATCKQGYQLIEGNQVLHSFTAVCQDDGTWHRAMPRCKIKDCGQPRNLPNGDFRYTTTMGVNTYKARIQYYCHEPYYKMQTRAGSRESEQGVYTCTAQGIWKNEQKGEKIPRCLPVCGKPVNPVEQRQRIIGGQKAKMGNFPWQVFTNIHGRGGGALLGDRWILTAAHTLYPKEHEAQS---NASLDVFLGHTNVEELMKLGNHPIRRVSVHPDYRQDESYNFEGDIALLELENSVTLGPNLLPICLPDNDTFYDLGLMGYVSGFGVMEEKIAHDLRFVRLPVANPQACENWLRGKNRMDVFSQNMFCAGHPSLKQDACQGDSGGVFAVRDPNTDRWVATGIVSWGIGCSRGYGFYTKVLNYVDWIKKEMEEED", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "***: *** :** . *** :****:*******:*****.::********* ******** ***:*****************::********.********.**********************************************:.:* **. **:****************:******:* :*************.***:******:.******************:*****:**:**********************:************************************:**** *******:********: ***********.********:****.* *******:**************:****:.*.****** ** **.**:* ***:******** ***** ** :*:************::***:************** *::*** ** *: ******.**. ********************:***.*: :. *..: *********:: ***:**:*** :********. *******************:*********:***. **********: *:*:*.**********:.:**:.**: *: . *******:*.*:::**************** * * *************..******************* :*:", "identical_positions": 573, "similar_positions": 92, "identity": "80.93%" }, { "cls_id": "homologset.agr.MGI:1355314", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZR08-1", "uniprot_id": "D3ZR08_RAT", "id": "D3ZR08-1", "name": "DNA damage-binding protein 2", "aln": "MAPKKCPETQKSPDVAVLLKSKSRRSPQELEPEAKKLFVQGPVSSRKCESCCLLAEL--SSLQIPPRSSSIVRDLYQQKLGKATWPSLQQGLQKSFLHSLASYRVFQKAAPFDRRTTSLAWHPTHPSTLAVGSKGGDIMIWNFGIKDKPIFLKGIGAGGSITGLKFNHLNTNQFFASSMEGTTRLQDFKGNILRIYTSSNSCKVWFCSLDVSAKSRVVVTGDNMGHVILTNTDGKELWNLRMHKKKVAHVALNPCCDWLLATASIDQTVKIWDLRQIKGKDSFLFSLPHRHPVNSACFSP-DGARLLTTDQNNEIRVYSASQWDSPLSLISHPHRHFQHLTPIKATWHSRHNLIVVGRYPDPNLKSCVPYELRTIDVFDGSSGKMMCQLYDPGYSGITSLNEFNPMGDTLASTMGYHILIWSPEEDGSLKDHERL----------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q99J79-1", "uniprot_id": "DDB2_MOUSE", "id": "Q99J79-1", "name": "DNA damage-binding protein 2", "aln": "MAPKKCPETQKSPDVAVLLRSKSRRGPQELEPEAKKLRVQGPVSSRTCESCCLLAEL--SSLQIPSRSSSIVRDLYQHKLGKATWSSLQQGLQKSFLHSLASYQVFRKAAPFDRRTTSLAWHPTHPSTLAVGSKGGDIMIWNFGIKDKPIFLKGIGAGGSITGLKFNHLNTNQFFASSMEGTTRLQDFKGNILRVYTSSNSCKVWFCSLDVSAKSRVVVTGDNMGHVILLSTDGKELWNLRMHKKKVAHVALNPCCDWLLATASIDQTVKIWDLRQIKGKDSFLYSLPHRHPVNAACFSP-DGARLLTTDQNNEIRVYSASQWDSPLNLISHPHRHFQHLTPIKATWHSRHNLIVVGRYPDPNLKSCVPYELRTIDVFDGSSGKMMCQLYDPGYSGITSLNEFNPMGDTLASTMGYHILIWSQEEDGSQKDHERL----------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q92466-1", "uniprot_id": "DDB2_HUMAN", "id": "Q92466-1", "name": "DNA damage-binding protein 2", "aln": "MAPKKRPETQKTSEIVLRPRNKRSRSPLELEPEAKKLCAKGSGPSRRCDSDCLWVGL--AGPQILPPCRSIVRTLHQHKLGRASWPSVQQGLQQSFLHTLDSYRILQKAAPFDRRATSLAWHPTHPSTVAVGSKGGDIMLWNFGIKDKPTFIKGIGAGGSITGLKFNPLNTNQFYASSMEGTTRLQDFKGNILRVFASSDTINIWFCSLDVSASSRMVVTGDNVGNVILLNMDGKELWNLRMHKKKVTHVALNPCCDWFLATASVDQTVKIWDLRQVRGKASFLYSLPHRHPVNAACFSP-DGARLLTTDQKSEIRVYSASQWDCPLGLIPHPHRHFQHLTPIKAAWHPRYNLIVVGRYPDPNFKSCTPYELRTIDVFDGNSGKMMCQLYDPESSGISSLNEFNPMGDTLASAMGYHILIWSQEEARTRK---------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q2YDS1-1", "uniprot_id": "DDB2_DANRE", "id": "Q2YDS1-1", "name": "DNA damage-binding protein 2", "aln": "MARGRAQTDSAASKQTKTVNSKKRPNEETPQPSTKKLKAKQQHKSKQKEETYIQASVKWTGGQKKVGQTSILHYIYKSSLGQSIHAQLRQCLQEPFIRSLKSYKLHRTASPFDRRVTSLEWHPTHPTTVAVGSKGGDIILWDYDVLNKTSFIQGMGPGDAITGMKFNQFNTNQLFVSSIWGATTLRDFSGSVIQVFAKTDSWDYWYCCVDVSVSRQMLATGDSTGRLLLLGLDGHEIFKEKLHKAKVTHAEFNPRCDWLMATSSVDATVKLWDLRNIKDKNSYIAEMPHEKPVNAAYFNPTDSTKLLTTDQRNEIRVYSSYDWSKPDQIIIHPHRQFQHLTPIKATWHPMYDLIVAGRYPD---DQLLLNDKRTIDIYDANSGGLVHQLRDPNAAGIISLNKFSPTGDVLASGMGFNILIWNREDTLSSVNRKQTIVTGEDVGGRAGGSRSQRSSQQRPSRDRRAAADEAKLKKKLSATETKSKTKSKTESKTSKSKKK", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "** : . :.. . ..* . :*.:*** .: *: :. : . : :. * **:: ::: .**:: ..::* **:.*:::* **:: :.*:*****.*** ******:*:*********::*::.: :*. *::*:*.*.:***:*** :****::.**: *:* *:**.*.::::::.::: . *:*.:***.. :::.***. *.::* . **:*::: ::** **:*. :** ***::**:*:* ***:****:::.* *:: .:**.:***:* *.* *.::******..******: :*. * :* ****:*********:**. ::***.***** .. : ****::*..** :: ** ** :** ***:*.* **.*** **::****. *: : ", "identical_positions": 182, "similar_positions": 155, "identity": "36.47%" }, { "cls_id": "homologset.agr.MGI:1355315", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "F7F0R0-1", "uniprot_id": "F7F0R0_RAT", "id": "F7F0R0-1", "name": "", "aln": "---------------------------------------------------------------------MALPFR-----------------KDLGDYKDLDEDELLGKLSESELKQLETVLDDLDPENALLPAGFRQKNQTSKSATGPFDRERLLSYLEKEALEYKDRED-YVPYTGEKKGKIFIP---KQKPVQTFTEETISLDPELEEALTSASDTELCDLAAILGMHSLIADTQFCD--------------------------------VLGSSNGDDQEHFPNVVKGEK------------------------------------ILPVFDEPPNPTNVEESLKRIRENDACLVEVNLNNIKNIPIPTLKDFAKTLETNTHVKHFSLAATRSNDPVAAAFADMLKVNKTLKSLNMESNFITGTGVLALIDALKDNETLSELKIDNQR-QQLGTSVELEMAKMLEENTNILKLGYQFTQQGPRTRAANAITKNNDLG-KMSLDYEVQSKFDSPPP------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9JHJ0-1", "uniprot_id": "TMOD3_MOUSE", "id": "Q9JHJ0-1", "name": "Tropomodulin-3", "aln": "---------------------------------------------------------------------MALPFR-----------------KDLGDYKDLDEDELLGKLSESELKQLETVLDDLDPENALLPAGFRQKNQTSKSATGPFDRERLLSYLEKQALEHKDRDD-YVPYTGEKKGKIFIP---KQKPAQTLTEETISLDPELEEALTSASDTELCDLAAILGMHNLIADTPFCD--------------------------------VLGSSNGVNQERFPNVVKGEK------------------------------------ILPVFDEPPNPTNVEESLKRIRENDARLVEVNLNNIKNIPIPTLKDFAKTLEANTHVKHFSLAATRSNDPVAVAFADMLKVNKTLKSLNMESNFITGAGVLALIDALRDNETLMELKIDNQR-QQLGTSVELEMAKMLEENTNILKFGYQFTQQGPRTRAANAITKNNDLVRKRRIEGDHQ--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9NYL9-1", "uniprot_id": "TMOD3_HUMAN", "id": "Q9NYL9-1", "name": "Tropomodulin-3", "aln": "---------------------------------------------------------------------MALPFR-----------------KDLEKYKDLDEDELLGNLSETELKQLETVLDDLDPENALLPAGFRQKNQTSKSTTGPFDREHLLSYLEKEALEHKDRED-YVPYTGEKKGKIFIP---KQKPVQTFTEEKVSLDPELEEALTSASDTELCDLAAILGMHNLITNTKFCN--------------------------------IMGSSNGVDQEHFSNVVKGEK------------------------------------ILPVFDEPPNPTNVEESLKRTKENDAHLVEVNLNNIKNIPIPTLKDFAKALETNTHVKCFSLAATRSNDPVATAFAEMLKVNKTLKSLNVESNFITGVGILALIDALRDNETLAELKIDNQR-QQLGTAVELEMAKMLEENTNILKFGYQFTQQGPRTRAANAITKNNDLVRKRRVEGDHQ--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "E7F7X0-1", "uniprot_id": "LMOD3_DANRE", "id": "E7F7X0-1", "name": "Leiomodin-3", "aln": "-------------MSERTEQESYTDKIDEDEILAGLSAEELKQLQSEMDDIAPDERVPVGLRQKDASHEMTVRDC-----------------TEPESEEEIDEDEILAGLSAEELKQLQSEMEEIAPD-ERVPVGMRQRDQTDKPPTGSFDHRSLVEYLYWEKESKRMLEEERVPTTLLPSQKTNEE---HEAKNEDKVEELELVYEEIVEEVEGGQGDAVVDEVIEEVIMEVEEEDKVCDKPVKTDLDATDPTVTSEDGLQRPSESADANVEAKTDQSGLDTETKVNEEKKEDSTEPAPSSYENWVPEKEERVISKLKIPKLALGGNTFVKKTARPSGNETNLESTLDKIRNNNPSVTDVNLNNIENIPKEMLLDYVNSLKKNRHVKTFSIANTGADENVAFTLANMLKENRSITTLNIESNFITGKGIVAIIRCLQFNETLTELRFHNQR-HMLGHHAEMEVSRLLKANNTLLKMGYHFELPGPRMVVTNLLTRNLDRQRQQRMEEQKLQQMKEQRKVMEMYEDSLNLPPGMLEMLGGYIPLSLLQNCQNGAEDIPEDSPEPSPQPSPPHQLCKTQHLAPQQHPPNLSTGNLFEEVQLKKTPKRRDPLLEWNQCDERKDGRPNVHLRSVPKKRSIAREGPVDERANLKDMIKTLKPVPRRREPPKVDLTPRDHLLSEIRQSNVAYLKAVPLPKILESQETSLF", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A0B4K6N4-1", "uniprot_id": "A0A0B4K6N4_DROME", "id": "A0A0B4K6N4-1", "name": "", "aln": "MSDIEDVFGGSAEETKPEPDAQSKTSVVTEHTEEVIPGETEKMVTETIDEDGDVVEETTEVTRKTVKRTMKITETSATTKTTTLTTPAKLYGKDLSEYDDVDVESLLAQLSPEEITILAKEVD---PDDNFLPPDQRNSYECTKEATGPLNRKQLIEHINKQAIETPDQPEFEPFVQGKVRGKKWVPPPRDARDIEAEEQIAIDMGEEYEHALNDATQEEIIDLAAILGFHSMMNQDQYHAS-----------------------------LLNKGQPVGLGWDGITKSTQQKLFP---------------------------------------MDPPNNTDVEESIKRVKDDDSKLIDLNLNNIKNISDEKLEQLFAALPQNEHLEVLSLTNVGLTDKTALLLAAAIEKSKTLRVLNVETNFISPPVIVKLVQALLKCHTIEEFRASNQRSAVLGNKIEMEITDLVEKNSSLLRLGLHLEFNDARHRVAAHLQRNIDRIFRVQKLKPNLPKLILPGN-MEIERDLVAYN--------------------------RSATPSPSPSPQPP------VDYEVEEDPDNMVIR----------------------------GGGDAFDPDVDPDNMVVPGSRSVTPNYDDEGVYQAHTWTSASHGPSDQELHRWRLAVGFIRLG-LGSLHILHRKKSIAYQ-----", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * : .: . .::* :.:*. ** *:. * . :: *: :* . *: : * .**.:::. *:.:: : . : * . : : : * . : .. : * . : .: : . * . : : : : . * *::*.::.: ::::. : ::*****:**. * : :* * *:: :*:: . : .* :* :: .::: **:*:***: :: :: .* .*: *:: *** ** *:*:: ::: *..:*::* :: ..* .: : :* * : ", "identical_positions": 57, "similar_positions": 121, "identity": "8.09%" }, { "cls_id": "homologset.agr.MGI:1355316", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0ABK0LQS8-1", "uniprot_id": "A0ABK0LQS8_RAT", "id": "A0ABK0LQS8-1", "name": "Alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 6", "aln": "MACSRPPSQCDPTTLPPGPPAGRWPLPFSRRRREMSSNKEQRSAVFVVLFALITILILYSSNSANEV---FHYGSLR--GRSRRPVNLKKWSFSNAYFPILGNKTLPSRCNQCVIVTSSSHLLGTKLGPEIERAECTIRMNDAPTTGYSADVGNKTTFRVVAHSSVFRVLRKPQEFVNRTPETVFIFWGPPNKMQ-KPQGSLLRVIQRAGLAFPNMEAYAVSQARMQQFDDLFRGETGKDSLRCKVERWFSGQGRLHSSRGPELGFQHPHQDRQLTATCDSSSREKSHSWLSTGWFTMVIAVELCDHVHVYGMVPPDYCSG-PACSGCRTTTMNPRGQMNVSPTSRTSTAVRAITTASSLRRGSSHPGLNSTVSPSPTPPGPNHPVHRPRTDTSEVALGPAI", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9JM95-1", "uniprot_id": "SIA7F_MOUSE", "id": "Q9JM95-1", "name": "Alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 6", "aln": "MACSRPPSQCDPTTLPPGPPAGRWPLPFSRRRREMSSNKEQRSAVFVILFALITILILYSSNSANEV---FHYGSLR--GRTRRPVNLKKWSFSSAYFPILGNKTLPSRCNQCVIITSSSHLLGTKLGPEIERAECTIRMNDAPTSGYSADVGNKTTFRVVAHSSVFRVLRKPQEFVNRTPETVFIFWGPPNKMQ-KPQGSLLRVIQRAGLMFPNMEAYAVSPARMQQFDDLFRGETGKD-------------------------------------------REKSHSWLSTGWFTMVIAVELCDHVHVYGMVPPDYCSQRPRLQRMPYHYYEPKG---------PDECVTYIQNEHS-RKGNHHRFITEKRVFSSWAQLYGITFSHPSWT----------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q969X2-1", "uniprot_id": "SIA7F_HUMAN", "id": "Q969X2-1", "name": "Alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 6", "aln": "MACSRPPSQCEPTSLPPGPPAGRRHLPLSRRRREMSSNKEQRSAVFVILFALITILILYSSNSANEV---FHYGSLR--GRSRRPVNLKKWSITDGYVPILGNKTLPSRCHQCVIVSSSSHLLGTKLGPEIERAECTIRMNDAPTTGYSADVGNKTTYRVVAHSSVFRVLRRPQEFVNRTPETVFIFWGPPSKMQ-KPQGSLVRVIQRAGLVFPNMEAYAVSPGRMRQFDDLFRGETGKD-------------------------------------------REKSHSWLSTGWFTMVIAVELCDHVHVYGMVPPNYCSQRPRLQRMPYHYYEPKG---------PDECVTYIQNEHS-RKGNHHRFITEKRVFSSWAQLYGITFSHPSWT----------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AC58IC42-1", "uniprot_id": "A0AC58IC42_DANRE", "id": "A0AC58IC42-1", "name": "", "aln": "-----------------------MTLQLVDKQWQQG----QRMVIYGAVFLITTLLILYSSSSSADLSRSFKTSNFRQIHHTLKTTNLKKWAGKDGYLPVYGNKSLNLHCHHCALVTSSSHVLGSQAGEEIDRTQCVFRMNNAPTSGHQSDVGNRTTVRVVAHSSVFSVVRKPAEFLNRSENPIIIFWGPSSKISREAKGTLYHLIQRVSMTYRNLSFFFISPSKMQKFDALFQKETGRD-------------------------------------------RKKSQSWLSTGWFTMVIAIEMCDNIKVYGMVPPNYCGRRPQPKRMPYHYYKPRG---------PDECVTYLQNERG-LRGSHHRFITEKQVFARWAKVYNISFTSPTW-----------", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * : :: : . ** .:: :* : *:******.*: :: *: ..:* :: :..*****: ...*.*: ***:* :*::*.:::****:**:: * **:*::*.:***:***:*:.:****:** ********* *:*:* **:**: :.::*****..*:. :.:*:* ::***..: : *:. : :* .:*::** **: ***:* *:**:*************:*:**:::*******:**. * . :*:* .. .* : . . :*. * :... : . . .. * ", "identical_positions": 124, "similar_positions": 113, "identity": "30.85%" }, { "cls_id": "homologset.agr.MGI:1355317", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "M0RCN2-1", "uniprot_id": "M0RCN2_RAT", "id": "M0RCN2-1", "name": "", "aln": "MGAGPSGGTGRRGGCMREGAVPNFSFKMSPRGHRNLLQFAKPKHWAIVVSSGEKELRLANPDPGLLSLSCSGMESVVQPSVFVVDGQTDIPFRRLGQNHRRRHCGTVQVSL-ALLLLLGAGLATEGWFLLRLHQRLGDIVAHLPDGGKGSWEKLIQDQRSHQPNPAAHLTGANASLIGIGGPLLWETQLGLAFLRGLTYHDGALVTTEAGYYYVYSKVQLSGVGCPQGLANGLPITHGLYKRTSRYPKELELLVSRRSPCGRANSS-RVWWDSSFLGGVVHLEAGEEVVVRVPGNRLVRPRDGTRSYFGAFMI", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9QYH9-1", "uniprot_id": "TNF14_MOUSE", "id": "Q9QYH9-1", "name": "Tumor necrosis factor ligand superfamily member 14", "aln": "------------------------------------------------------------------------MESVVQPSVFVVDGQTDIPFRRLEQNHRRRRCGTVQVSL-ALVLLLGAGLATQGWFLLRLHQRLGDIVAHLPDGGKGSWEKLIQDQRSHQANPAAHLTGANASLIGIGGPLLWETRLGLAFLRGLTYHDGALVTMEPGYYYVYSKVQLSGVGCPQGLANGLPITHGLYKRTSRYPKELELLVSRRSPCGRANSS-RVWWDSSFLGGVVHLEAGEEVVVRVPGNRLVRPRDGTRSYFGAFMV", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O43557-1", "uniprot_id": "TNF14_HUMAN", "id": "O43557-1", "name": "Tumor necrosis factor ligand superfamily member 14", "aln": "-----------------------------------------------------------------------MEESVVRPSVFVVDGQTDIPFTRLGRSHRRQSCSVARVGLGLLLLLMGAGLAVQGWFLLQLHWRLGEMVTRLPDGPAGSWEQLIQERRSHEVNPAAHLTGANSSLTGSGGPLLWETQLGLAFLRGLSYHDGALVVTKAGYYYIYSKVQLGGVGCPLGLAS--TITHGLYKRTPRYPEELELLVSQQSPCGRATSSSRVWWDSSFLGGVVHLEAGEKVVVRVLDERLVRLRDGTRSYFGAFMV", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ****:************** ** :.***: *...:*.* *:**:*****.:*****:** ***::*::**** ****:***::***: **********:** * ********:*********:*******. :.****:******.***** ***. .*********.***:*******::******.** *******************:***** .:**** ************:", "identical_positions": 181, "similar_positions": 41, "identity": "57.83%" }, { "cls_id": "homologset.agr.MGI:1355318", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O70394-1", "uniprot_id": "I27RA_MOUSE", "id": "O70394-1", "name": "Interleukin-27 receptor subunit alpha", "aln": "MNRLR-----VARLTPLELLLSLMSLLLGTRPHGSPGPLQCYSVGPLGILNCSWEPLGDLETPPVLYHQSQKYHPNRVWEVKVPSKQSWVTIPREQFTMADKLLIWGTQKGRPLWSSVSVNLETQMKPDTPQIFSQVDISEEATLEATVQWAPPVWPPQKVLICQFRYKECQAETWTRLEPQLKTDGLTPVEMQNLEPGTCYQVSGRCQVENG-YPWGEWSSPLSFQTPFLDPEDVWVSGTVCETSGKRAALLVWKDPRPCVQVTYTVWFGAGDITTTQEEVPCCKSPVPAWMEWAVVSPGNSTSWVPPTNLSLVCLAPESAPCDVGVSSADGSPGIKVTWKQGTRKPLEYVVDWAQDGDSLDKLNWTRLPPGNLSTLLPGEFKGGVPYRITVTAVYSGGLAAAPSVWGFREELVPLAGPAVWRLPDDPPGTPVVAWGEVPRHQLRGQATHYTFCIQSRGLSTVCRNVSSQTQTATLPNLHLGSFKLWVTVSTVAGQGPPGPNLSLHLPDNRIRWKALPWFLSLWGLLLMGCGLSLASTRCLQARCLHWRHKLLPQWIWERVPDPANSNSGQPYIKEVSLPQPPKDGPILEVEEVELQPVVESPK---ASAPIYSGYEKHFLPTPEELGLLV--------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6UWB1-1", "uniprot_id": "I27RA_HUMAN", "id": "Q6UWB1-1", "name": "Interleukin-27 receptor subunit alpha", "aln": "MRGGRGAPFWLWPLPKLALLPLLWVLFQRTRPQGSAGPLQCYGVGPLGDLNCSWEPLGDLGAPSELHLQSQKYRSNKTQTVAVAAGRSWVAIPREQLTMSDKLLVWGTKAGQPLWPPVFVNLETQMKPNAPRLGPDVDFSEDDPLEATVHWAPPTWPSHKVLICQFHYRRCQEAAWTLLEPELKTIPLTPVEIQDLELATGYKVYGRCRMEKEEDLWGEWSPILSFQTPPSAPKDVWVSGNLCGTPGGEEPLLLWKAPGPCVQVSYKVWFWVGGRELSPEGITCCCSLIPSGAEWARVSAVNATSWEPLTNLSLVCLDSASAPRSVAVSSIAGSTELLVTWQPGPGEPLEHVVDWARDGDPLEKLNWVRLPPGNLSALLPGNFTVGVPYRITVTAVSASGLASASSVWGFREELAPLVGPTLWRLQDAPPGTPAIAWGEVPRHQLRGHLTHYTLCAQSGTSPSVCMNVSGNTQSVTLPDLPWGPCELWVTASTIAGQGPPGPILRLHLPDNTLRWKVLPGILFLWGLFLLGCGLSLATS----GRCYHLRHKVLPRWVWEKVPDPANSSSGQPHMEQVPEAQPLGDLPILEVEEMEPPPVMESSQPAQATAPLDSGYEKHFLPTPEELGLLGPPRPQVLA", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*. * : *. * ** * *: ***:**.******.***** *********** :*. *: *****:.*:. * *.: :***:*****:**:****:***: *:***..* *********::*:: .:**:**: .*****:****.**.:*******:*:.** :** ***:*** *****:*:** .* *:* ***::*: *****. ****** *:******.:* *.* . .**:** * *****:*.*** .*. : * :.** * :*: *** **. *:*** * ******** . *** .*.*** **. : ***: *. :***:*****:***.*:****.********:****:*. *********** :.***:*.*********.**.**::*** * *****.:************: ****:* ** .:** ***.:**:.***:* *. :****.**:******** * ****** :***.** :* ****:*:*******:: .** * ***:**:*:**:*******.****::::*. .** * *******:* **:**.: *:**: ***************** ", "identical_positions": 391, "similar_positions": 133, "identity": "61.09%" }, { "cls_id": "homologset.agr.MGI:1355319", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9JHI7-1", "uniprot_id": "EXOS9_MOUSE", "id": "Q9JHI7-1", "name": "Exosome complex component RRP45", "aln": "-MKETPLSNCERRFLLRAIEEKKRLDGRQTYDYRNIRISFGTDYGCCIVELGKTRVLGQVSCELVSPKLNRATEGILFFNLELSQMAAPAFEPGRQS-DLLVKLNRLLERCLRNSKCIDTESLCVVAGEKVWQIRVDLHLLNHDGNIIDAASIAAIVALCHFRRPDVSVQGEEVTLYTPEERDPVPLSIHHMPICVSFAFFQQG------------TYLLVDPNEREERVMDGLLVIAMNKHREICTIQSSGGIMLLKDQVFRCSKIAGVKVAEITELIQKALENDQRVRKEGGKFGFAESIANQRITAFKMETAPIDTSNIEERAEEIIAEAEPPPEVVSQPVLWTPGTAQIGDGIENSWGDLEDSEKEEEEEEGGIDEAVILDDTKMDTG-EVSDIGSQGAPIVLSDSEEEEMIILEPEKNPKKIRAQTSAN--QKAPSKGQGKRKKKKRTAN", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q4QR75-1", "uniprot_id": "EXOS9_RAT", "id": "Q4QR75-1", "name": "Exosome complex component RRP45", "aln": "-MKETPLSNCERRFLLRAIEEKKRLDGRQTYDYRNIRISFGTDYGCCIVELGKTRVLGQVSCELVSPKLNRATEGILFFNLELSQMAAPAFEPGRQS-DLLVKLNRLLERCLRNSKCIDTESLCVVAGEKVWQIRVDLHLLNHDGNIIDAASIAAIVALCHFRRPDVSVQGEEVTLYTPEERDPVPLSIHHMPICVSFAFFQQG------------TYLLVDPNEREERVMDGLLVIAMNKHREICTIQSSGGIMLLKDQVFRCSKIAGVKVAEITELIQKALENDQRVRKEGGKFGFAESIANQRITAFKMEKAPIDTSNIEEKAEEIIAEAEPPPEVVSKPVLWTPGTAQIGEGIENSWGDLEDSEKEEEEE-GGIDETVILDDTKMDTG-EVSDIGSQGAPIVLSDSEEEEMIILEPEKSPKKIRAQTSAN--QKAPSKSQGKRRKKKRTAN", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q06265-1", "uniprot_id": "EXOS9_HUMAN", "id": "Q06265-1", "name": "Exosome complex component RRP45", "aln": "-MKETPLSNCERRFLLRAIEEKKRLDGRQTYDYRNIRISFGTDYGCCIVELGKTRVLGQVSCELVSPKLNRATEGILFFNLELSQMAAPAFEPGRQS-DLLVKLNRLMERCLRNSKCIDTESLCVVAGEKVWQIRVDLHLLNHDGNIIDAASIAAIVALCHFRRPDVSVQGDEVTLYTPEERDPVPLSIHHMPICVSFAFFQQG------------TYLLVDPNEREERVMDGLLVIAMNKHREICTIQSSGGIMLLKDQVLRCSKIAGVKVAEITELILKALENDQKVRKEGGKFGFAESIANQRITAFKMEKAPIDTSDVEEKAEEIIAEAEPPSEVVSTPVLWTPGTAQIGEGVENSWGDLEDSEKEDDEG--GGDQAIILDGIKMDTGVEVSDIGSQDAPIILSDSEEEEMIILEPDKNPKKIRTQTTSAKQEKAPSKKPVKRRKKKRAAN", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q5XJQ5-1", "uniprot_id": "EXOS9_DANRE", "id": "Q5XJQ5-1", "name": "Exosome complex component RRP45", "aln": "-MRDTPLSNCERLFLLKAIKEKKRLDGRQTYDYRNIKISFGTDYGCCVVELGKTRVLSQVSCELVPPKDSRPTEGIVFFNLELSPMASPAFEPNRQS-ELLVTLNRQLERCLRNSKCIDTESLCVVSGEKVWQIRVDVHVLNHDGNLMDAASIAAISALSHFRRPDVAIQGRDVTVFGPEERDPIPLSIYHMPICVSFAFFLQG------------SFLLVDPCEREERVKDGLLVIAMNKHREICSIQSSGGIMLLKEQVLRCSKIASVKVSEITELINKALENDKKVRKEGGKFGFAESMPKERITTLKRDEAPVEMTDVKETADDIVQRTETTTETVPSPILVATGTAQIGEGIVNSWG-LDEDE----------DDELQTEDRKTDEV------------VVITDSEEEEVVILNDQK------------------SKKTSKQK-------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q05636-1", "uniprot_id": "RRP45_YEAST", "id": "Q05636-1", "name": "Exosome complex component RRP45", "aln": "MAKDIEISASESKFILEALRQNYRLDGRSFDQFRDVEITFGKEFGDVSVKMGNTKVHCRISCQIAQPYEDRPFEGLFVISTEISPMAGSQFENGNITGEDEVLCSRIIEKSVRRSGALDVEGLCIVAGSKCWAVRADVHFLDCDGGFIDASCIAVMAGLMHFKKPDITVHGEQIIVHPVNEREPVPLGILHIPICVTFSFFNPQDTEENIKGETNSEISIIDATLKEELLRDGVLTVTLNKNREVVQVSKAGGLPMDALTLMKCCHEAYSIIEKITDQILQLLKEDSEKRNK-----YAAMLTSENAREI-------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :: :* .* *:*.*:.:: *****. ::*::.*:**.::* *::*:*:* ::**::. * .*. **:..:. *:* **.. ** .. : : * .* :*:.:*.* .:*.*.**:*:*.* * :*.*:*.*: **.::**:.**.: .* **::**::::* :: :. :**:*:**.* *:****:*:** ::*. :** : **:*.:::**:**: :..:**: : :::*.: * : :**: * : *::*.. *:: :* :..:. : ", "identical_positions": 95, "similar_positions": 126, "identity": "20.88%" }, { "cls_id": "homologset.agr.MGI:1355321", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9Z265-1", "uniprot_id": "CHK2_MOUSE", "id": "Q9Z265-1", "name": "Serine/threonine-protein kinase Chk2", "aln": "MKSHHQSHSSTSSKAHDSASCSQSQGGFSQPQGTPSQLHELSQYQGSSSSSTGTVPSSSQSSHSSSGTLSSLETVSTQELCSIPEDQEPE-----EPGPAPWARLWALQDGFSNLDCVNDNYWFGRDKSCEYCFDGPLLRRTDKYRTYSKKHFRIFREMGPKNCYIVYIEDHSGNGTFVNTELIGKGKRCPLSNNSEIA---LSLCRNKVFVFFDLTVDDQSVYPKELRDEYIMSKTLGSGACGEVKMAFERKTCQKVAIKIISKRRFALGSSREADTAPS-VETEIEILKKLNHPCIIKIKDVFDAED------YYIVLELMEGGELFDRVVGNKRLKEATCKLYFYQMLVAVQYLHENGIIHRDLKPENVLLSSQ----------------EEDCLIKITDFGQSKILGETSLMRTLCGTPTYLAPEVLVSNGTAGYSRAVDCWSLGVILFICLSGYPPFSEHKTQVSLKDQITSGKYNFIPEVWTDVSEEALDLVKKLLVVDPKARLTTEEALNHPWLQDEYMKKKFQDLLVQEKNSVTLPVAPAQTS-SQKRPLELEVEGMPSTKRLSVCGAVL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O96017-1", "uniprot_id": "CHK2_HUMAN", "id": "O96017-1", "name": "Serine/threonine-protein kinase Chk2", "aln": "---MSRESDVEAQQSHGSSACSQPHGSVTQSQGSS------SQSQGISSSSTSTMPNSSQSSHSSSGTLSSLETVSTQELYSIPEDQEPEDQEPEEPTPAPWARLWALQDGFANLECVNDNYWFGRDKSCEYCFDEPLLKRTDKYRTYSKKHFRIFREVGPKNSYIAYIEDHSGNGTFVNTELVGKGKRRPLNNNSEIA---LSLSRNKVFVFFDLTVDDQSVYPKALRDEYIMSKTLGSGACGEVKLAFERKTCKKVAIKIISKRKFAIGSAREADPALN-VETEIEILKKLNHPCIIKIKNFFDAED------YYIVLELMEGGELFDKVVGNKRLKEATCKLYFYQMLLAVQYLHENGIIHRDLKPENVLLSSQ----------------EEDCLIKITDFGHSKILGETSLMRTLCGTPTYLAPEVLVSVGTAGYNRAVDCWSLGVILFICLSGYPPFSEHRTQVSLKDQITSGKYNFIPEVWAEVSEKALDLVKKLLVVDPKARFTTEEALRHPWLQDEDMKRKFQDLLSEENESTALPQVLAQPSTSRKRPREGEAEGAETTKRPAVCAAVL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M2BC68-1", "uniprot_id": "A0A8M2BC68_DANRE", "id": "A0A8M2BC68-1", "name": "", "aln": "-----------MSEEAGPSGESQSQ-TQSQTQSQP------------ASSSSSAPTSSSQGSSSGSGTLSSVDTVPVQELQSIPEDEE-------EVQPQVWGRIIPLKQGFSVLNCTENQYSFGRDKRCDYSFSNSILKKSPYFNTYSKKHFRIFRDEN-----LVYLEDLSGNGTWVDDEKLGNGKQSLLSNNSVIA---LAEQKHQVFMFIDKMADDQANLPLEFSKKYHIARKIGTGVCGEVKLAIEKETFKKVALKTINKHDFPS----IGTATRN-AEREIEILKKIDHPCLIKTEDFYQTEDS-----YYIVLEYIEGGELFGRIKAKKKLEEDIAKLYFYQMLKAVEYLHNNGIIHRDLKPENVLLASH----------------DDICLIKITDFNQSKILEESSLMKTLCGTPTYVAPEVFTHASTVGYTKAVDYWSLGVLLFICLGGYPPFNTECTTMSVREQIINGEYRFIPSQWKNVSNEAKDLVKKLLVVDPQKRLSVEEALEHPWLKDDRMRQNANQLMN-----PGAANQPMRPEATRQKRKAHEGEGEPSSKRKPGP----", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "O61267-1", "uniprot_id": "LOK_DROME", "id": "O61267-1", "name": "Ovarian-specific serine/threonine-protein kinase Lok", "aln": "-----------MARDTQGTQGTQSQASNIWTQVES-------------------QPMEKIVWGRLYGKNIKIKSLGTSSKY----------------------RIIYTHSSFS-VDLNNDEFTAGRGEANDLILTLNDLP--EKILTRISKVHFIIKRANCELTNPVYIQDLSRNGTFVNNEKIGTNRMRILKNDDVIS---LSHPTYKAFVFKDLSPNESIGLPEEINKTYYVNRKLGSGAYGLVRLVYDTRTCQQFAMKIVKKNMLSGARPSTNFSDPDRVLNEAKIMKNLSHPCVVRMHDIVDKPDS-----VYMVLEFMRGGDLLNRIISNKLLSEDISKLYFYQMCHAVKYLHDRGITHRDLKPDNVLLETN----------------DEETLLKVSDFGLSKFVQKDSVMRTLCGTPLYVAPEVLITGGREAYTKKVDIWSLGVVLFTCLSGTLPFSDEYGTP-AAQQIKKGRFAYGHPSWKSVSQRAKLLINQMLIVDPERRPSIDDVLQSSWLRDAPMLQKAKRLMKLDGMEIEEENFLEPPTKRSRR----------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P39009-1", "uniprot_id": "DUN1_YEAST", "id": "P39009-1", "name": "DNA damage response protein kinase DUN1", "aln": "-------MSLSTKREHSGDVTDSSFKRQQRSNKPS----------SEYTCLGHLVNLIPGKEQKVEITNRNVTTIGRSRSCDVILSEP---------------DISTFHAEFHLLQMDVDNFQRNLINVIDKSRNGTFINGNRLVKKDYILKNGDRIVFGKSCSFLFKYASSSSTDIENDDEKVSSESRSYKNDDEVFKKPQISATSSQNATTSAAIRKLNKTRPVSFFDKYLLGKELGAGHYALVKEAKNKKTGQQVAVKIFHAQ------QNDDQKKNKQFREETNILMRVQHPNIVNLLDSFVEPISKSQIQKYLVLEKIDDGELFERIVRKTCLRQDESKALFKQLLTGLKYLHEQNIIHRDIKPENILLNITRRENPSQVQLGPWDEDEIDIQVKIADFGLAKFTGEMQFTNTLCGTPSYVAPEVLTKKG---YTSKVDLWSAGVILYVCLCGFPPFSDQLGPPSLKEQILQAKYAFYSPYWDKIDDSVLHLISNLLVLNPDERYNIDEALNHPWFND--IQQQSSVSLELQRLQITDNKIPKTYSELSCL----------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . .. .: . . .: :: . : : * :: ::: . : : : . . . * .. : * :.. .::. : :: : . . * : . * : : :*:* . *: . : .* ::.*:* . . . * :*: .:.** ::. : *:*** : .*:*: :: :. * : .* * *: .::***:..* ***:**:*:** : :*::**. :*: : .. .****** *:****: . *. ** ** **:*: ** * **. . :** ...: : * .:.: . *:.::*:::*. * . ::.*. .*:.* : :: . : ", "identical_positions": 75, "similar_positions": 141, "identity": "12.98%" }, { "cls_id": "homologset.agr.MGI:1355322", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D4A1X2-1", "uniprot_id": "EXOSX_RAT", "id": "D4A1X2-1", "name": "Exosome complex component 10", "aln": "MAPPSP---REHQSAPATGATKPDAE-MVLPGFPDADSFVKFALGSVVAVTKASGGLPQVGDEYDFYRSFP-AFQAFCETQGDRLLQCMSRVMQYHGCRSNIKDRSKVTELEDKFDLLVDTNDVILERVGILLDEASGVNKHQQPVLPAGLQVP-----------------KTIVSSWNRKAGEYGKKAKAETFRLLHAKNILRPQLRFREKIDN-SNTPFLPKIFVKPNARKPLPQALSKERRERPQDRPEDLDVPPALADFIHQQRAQQVEQDVFAHPYQYELDHFTPPPSVLQRPQPQLYRPVEETPCHVVSSLDELVELNEKLLGCQEFAVDLEHHSYRSFLGLTCLMQISTRTEDFIVDTLELRSDMYILNESLTDPAIVKVFHGADSDIEWLQKDFGLYVVNMFDTHQAARLLNLARHSLDHLLRLYCGVESNKQYQLADWRIRPLPEEMLNYARDDTHYLLYIYDRMRLELWERGNDQPVQLQVVWQRSRDICLKKFVKPIFTDESYLELYRKQ-------KKHLNSQQLTAFQLLFAWRDKTARREDESYGYVLPNHMMLKIAEELPKEPQGIIACCNPVPPLVRQQINEMHLLIQQAREMPLLKSETAAGVKKSGPLPSAER-LENDLFGPHDCSHAPPD--------------------NYPVTSTDGTMPLQKQPSLFDEGKEETS----VDARCLLATAVITLFSEPSTEEAGKTPLTVAQKKAQSIMESFENPFRMFLPSLENKAHISQAAKFDPSSKIYEISNRWKLAS--QVQKEPKEAAKKKVAEQTAAREETKE-ESTAAVLEQPIPVRQQAALEN---ATKKRERATSDLR-----------------TIEQKQEK--KRLKSSKKAKDPDPPGKDFSPYDYSQSDFGAFAGDSKSKPS-SQFDPNKVAPSGKKCFGAKKFKQSVGNKSMSFPAGKSDRGFRHNWPKR", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P56960-1", "uniprot_id": "EXOSX_MOUSE", "id": "P56960-1", "name": "Exosome complex component 10", "aln": "MAPPSP---REHQSAPATSATKPDAE-MVLPGFPDADSFVKFALGSVVAVTKASGGLPQFGDEYDFYRSFP-AFQAFCETQGDRLLQCMSRVMQYHGCRSNIKDRSKVTELEDKFDLLVDTNDVILERVGMLLDEASGVNKHQQPVLPAGLQVP-----------------KTIVSSWNRKAGEYGKKAKSETFRLLHAKNIVRPQLRFREKIDN-SNTPFLPKIFVKPNARKPLPLALSKERRERPQDRPEDLDVPPALADFIHQQRTQQVEQDMFAHPYQYELDHFTPPQSVLQRPKPQLYRAVGETPCHLVSSLDELVELNEKLLGCQEFAVDLEHHSYRSFLGLTCLMQISTRTEDFIVDTLELRSDMYILNESLTDPAIVKVFHGADSDIEWLQKDFGLYVVNMFDTHQAARLLNLARHSLDHLLRLYCGVESNKQYQLADWRIRPLPEEMLSYARDDTHYLLYIYDRMRLELWERGNHQPVQLQVVWQRSRDICLKKFVKPIFTDESYLELYRKQ-------KKHLNSQQLTAFQLLFAWRDKTARREDESYGYVLPNHMMLKIAEELPKEPQGIIACCNPVPPLVRQQINEMHLLIQQAREMPLLKSENAAGVRKSGPLPSAER-LENDLFGPHDCSHAPPD--------------------NYQNTSTDGTLPLQKQPSLFTEGKEETS----VDAGCLLATAVITLFSEPNTEEGGKTPLTVAQKKAQNIMQSFENPFRMFLPSLEHKAHISQAAKFDPSSKIYEISNRWKLASQVQVQKEPKEATKKKVAEQTAAREEAKE-EAAAGVLEQAIPVRQQAALEN---ATKKRERATSDLR-----------------TIEQKQEK--KRLKSSKKAKDPDPPGKDFSPYDYSQSDFRAFAGDSKSKPS-SQFDPNKLAPSGKKGVGAKKCKQSVGNKSMSFAVGKSDRGFRHNWPKR", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q01780-1", "uniprot_id": "EXOSX_HUMAN", "id": "Q01780-1", "name": "Exosome complex component 10", "aln": "MAPPST---REPRVLSATSATKSDGE-MVLPGFPDADSFVKFALGSVVAVTKASGGLPQFGDEYDFYRSFP-GFQAFCETQGDRLLQCMSRVMQYHGCRSNIKDRSKVTELEDKFDLLVDANDVILERVGILLDEASGVNKNQQPVLPAGLQVP-----------------KTVVSSWNRKAAEYGKKAKSETFRLLHAKNIIRPQLKFREKIDN-SNTPFLPKIFIKPNAQKPLPQALSKERRERPQDRPEDLDVPPALADFIHQQRTQQVEQDMFAHPYQYELNHFTPADAVLQKPQPQLYRPIEETPCHFISSLDELVELNEKLLNCQEFAVDLEHHSYRSFLGLTCLMQISTRTEDFIIDTLELRSDMYILNESLTDPAIVKVFHGADSDIEWLQKDFGLYVVNMFDTHQAARLLNLGRHSLDHLLKLYCNVDSNKQYQLADWRIRPLPEEMLSYARDDTHYLLYIYDKMRLEMWERGNGQPVQLQVVWQRSRDICLKKFIKPIFTDESYLELYRKQ-------KKHLNTQQLTAFQLLFAWRDKTARREDESYGYVLPNHMMLKIAEELPKEPQGIIACCNPVPPLVRQQINEMHLLIQQAREMPLLKSEVAAGVKKSGPLPSAER-LENVLFGPHDCSHAPPD--------------------GYPIIPTSGSVPVQKQASLFPDEKEDNL----LGTTCLIATAVITLFNEPSAEDSKKGPLTVAQKKAQNIMESFENPFRMFLPSLGHRAPVSQAAKFDPSTKIYEISNRWKLAQ-VQVQKDSKEAVKKKAAEQTAAREQAK--EACKAAAEQAISVRQQVVLEN---AAKKRERATSDPR-----------------TTEQKQEK--KRLKISKKPKDPEPPEKEFTPYDYSQSDFKAFAGNSKSKVS-SQFDPNKQTPSGKKCIAAKKIKQSVGNKSMSFPTGKSDRGFRYNWPQR", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F1Q5Q7-1", "uniprot_id": "F1Q5Q7_DANRE", "id": "F1Q5Q7-1", "name": "Exosome complex component 10", "aln": "MAASSSSAAVAKQSDHSPSAEETEAETEFCPGFKDVDTFVKHGLGAVVSATKASAALPSAGDEFDLYRSFS-SFQQFCASQGDRLLHCMSQIMQHHGCRSHMRDRNKLTGLEDRFDLVVDANDAILEKVGILLDEASGVSRSQQPVMPAGYQPP-----------------KIIVSSWNRKGGGS----RAQTFQLLAAKNIQRPQLKFRDKVDN-SNTPFLSKIFIKPNAVKPLPSYFADKHIRK--ERPEDLDVPAALADFIHQQRTKEHVDDMFSHPYQYELDHLVMPENLKCKPEVQMYKPIDETPCQFISTLEDLVALNEKLAKTTEFAVDLEHHSYRSFLGITCLMQISTREEDFIIDTLELRSEMYILNETFTDPAIVKVFHGADSDIEWLQKDFGLYVVNMFDTHHAARCLNLGRNSLDHLLKVYCDVSSDKRYQLADWRIRPLPDEMLKYAQADTHYLLYVYDRVRADLFDGGNGQATLIQQVWTKSRDLSLKKYVKPIFTEDSYMELYRKQ-------KKSFNTQQLAAFRLMYAWRDKLAREEDESTGYILPNHMMMKIADELPKEPQGIIACCNPTPPLVRQQINELHQLIKQARETPLLKAEVVAQKRKS--MTPKRK-PQSTLFGPHDTSRSSES--------------------DFLDLSSFETP--TKPGMLFSEEDEESVDREKKSVHGLTAPAKISLFAEDVSPAS--AHLTVAQQKSHSIMESFENPFRMYLPSKD--IHISKNAKYDPSSKIYEIHNRWKLQSIEQQQKEAQAKQQAKEQAKKAQEERKKAKQTYQESLQNVHTVREQVKEAKQ--AGQKRERAASDVSEDSLKPNVKLSKSEGETTVADQSTKPAKKKQKQKTAQEPEAPKQDFKPYDYSQSNFKLFAG--KSKDG-SHFDPNRQGPKQKKNLKGQK-KGGGGGRSMSYVPAKSDRGFRHNWPKR", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VFF3-1", "uniprot_id": "EXOSX_DROME", "id": "Q9VFF3-1", "name": "Exosome complex component 10 homolog", "aln": "-MPRTPKRVHQEAKEESAQADQPPKK----SASEDVEAFTNKGFKNAIAATKAANAFPQG-TARALYLSYP-GYARVMEDLTQRVVALIGNVLHSKDIKGDIKKR----QPEEQFEMVQECNDVLFERITTNLDIKGGLRRNTQQVVEAQVDVMSSSTSIEPAVASPQTQGTPKAGSWNRTTGTPQR--SMVSARLFTAKNIVRPQTQFREPVDNSAQNPFVPRLKEKPNSLKPLALLP---------------------------EYDDAGNVQSYLHPYEFELLKFQPPEEQFQKQKPVLPALMAETELMVVDTVEKLKQALEELRQAPQIAIDVEHHSYRTFMGITCLVQMSTRSKDYIFDTLILRDDMHILNLVLTDPKKLKILHGADLDIEWLQRDLSLYIVNMFDTHRAAKALNMARLSLAYLLKHYLDLDVDKSLQLADWRMRPLPQQLVDYARQDTHFLIYVYGRMTNDLLQQ-HAEPGLLGSVYQQSTDVCKKRYNKPHIGPESHLDLVRKT-------KRSFDNRQLYALRGIFEWRDATARSEDESYGYVLPNHMMLQIAESLPREMQGILACCNPIPPLVRQQLHTLHQIVLKARDQPLVKPILEAHSSTQAALPPSTKDFSSKLYCPHDFSQLEEIRDDLPTLLKRNSTTGKLEVPNKEEVAKVDPTLAAPAMALFEKQSKPTQEEEQRWAHLRKESQTMRMPYKRYLAILPLMVQLKADQLARERSELQKRQLCPAAPTVEQNIKLEAHAIGKEDDDMYSVPLKEQLKRKHPQANVKTDPEQQPTASKRPRKDENSQ-TKPPVKIEPVEKVQQALGESDDEVVEVPIERQATEPPK----------------PSPAQNNRKQKKNQFQRGFKAKNRGNHPQSSSQQVPQHKGTGNFDYKNVDF-RQFKGGAQRARGTEIKQQIRGKNRPNNRNNKQFNKLFTFSNVRKEGKK", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q12149-1", "uniprot_id": "RRP6_YEAST", "id": "Q12149-1", "name": "Exosome complex exonuclease RRP6", "aln": "------------------------------MTSENPDVLLSRVINVVRAASSLAS------QDVDFYKNLDRGFSKDLKSKADKLADMANEIILSIDEH------------HESFELKEEDISDLWNNFGNIMDNLLEMSDHSLDKLNCAINSK-------------------------SRGSDLQYLGEFSGKNFSPTKRVEKPQLKFKSPIDNSESHPFIPLLKEKPNALKPLSESLR-------------------------LVDDDENNPSHYPHPYEYEIDHQEYSPEILQIREEIPSKSWDDSVPIWVDTSTELESMLEDLKNTKEIAVDLEHHDYRSYYGIVCLMQISTRERDYLVDTLKLRENLHILNEVFTNPSIVKVFHGAFMDIIWLQRDLGLYVVGLFDTYHASKAIGLPRHSLAYLLENFANFKTSKKYQLADWRIRPLSKPMTAYARADTHFLLNIYDQLRNKLIESNKLAGVLYESRNVAKRRFEYSKYRPLTPSSEVYSPIEKESPWKILMYQYNIPPEREVLVRELYQWRDLIARRDDESPRFVMPNQLLAALVAYTPTDVIGVVSLTNGVTEHVRQNAKLLANLIRDALRN------IKNTNEEATPIPSSETKADGILLETISVPQIRDV------------------------------------------------------------MERFSVLCNSNISKSRAKPVTNSSILLGKILPREEHDIAYSKDGLPNKVKTEDIRIRAQNFKSALANLEDIIFEIEKPLVVPVKLEEIKTVDPASAPNHSPEIDNLDDLVVLKK-----------------------------------------------------KNIQKKQPAKEKGVTEKDAVDYSKIPNILSNKPGQNNRQQKKRRFDPSSSDSNGPRAAKKRRPAAKGKNLSFKR----------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : : . : . :.:. : :* . .: ::: ..:: . : .: *:: : . : :.. :* : : . : . .: :*.: :** :*:. :** . **:. : ***: ***. . . : ***::*: : . : :: :.: .* *.* ::*:*:***.**:: *:.**:*:*** .*::.*** **.:::*** :*:* :*::*** ** ***:*:.**:*.:***::*:: :.: * ** :**. : ... .* ******:***.. : **: ***:*: :*.:: .: : : . . .:: : : : :: : : .: .: :: *** ** :*** :::**::: :. * : *::: * . ***: : : :: .* :.. .. * . . .: : : : :. . :. : . . . . : : . :. *. : .: : : . . : :*. . . . : . . . ", "identical_positions": 108, "similar_positions": 214, "identity": "11.18%" }, { "cls_id": "homologset.agr.MGI:1355323", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8M9PMI3-1", "uniprot_id": "A0A8M9PMI3_DANRE", "id": "A0A8M9PMI3-1", "name": "Large neutral amino acids transporter small subunit 2", "aln": "-------------------------MSSGGTRRRTASVPDSD--PDG---------EPAVTLKKEIGLLSACGIVVGNIIGSGIFVSPKGVLENSG-SVGLALIVWILTGIITAIGALCYAELGVTIPKSGGDYSYVNDIFGGLAGFLRLWIAVLVIYPTNQAVIALTFANYALQPLFPSCFPP-ERALGLLAAVCLLLLTWINCSSVRWATRVQDVFTTGKLLALGLIIIMGIVQICKG-HFYWLEPEHAFHPLQPYDMGRIALAVLQGSFAYAGWNFLNYVTEELIDPYRNLPRAIFISIPLVTFVYVSANIAYVTAMSPQELLAS-NAVAVTFGEKLLG--VMSWLMPISVALSTFGGVNGSLFTSSRLFFAGAREGHLPRLLAMIHVNRCTP----IPALLITCISTLLMLCV-SDIYTLIN-YVGFINYLFYGVTVAGQIVLRIREP----DIYRPIKVSLAWPAVFLIFWAFLLIFSLYSEP------VVCCIGLAIMLSGVPVYLFGIYWENKPKSFSSFVARLTHLGQKLCLVVYPGEDREDGNEDRE------------EDG------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "E7EXU6-1", "uniprot_id": "E7EXU6_DANRE", "id": "E7EXU6-1", "name": "Large neutral amino acids transporter small subunit 2", "aln": "-------------------------MTDGPRQRGSAAPSTAS--EDGGAADTGNTAGQSVALKKEIGLVSACGIIVGNIIGSGIFVSPKGVLENAS-SVGLALIVWILTGIITAIGALCYAELGVTIPKSGGDYSYVKDIFGGLAGFLRLWIAVLVIYPTNQAVIALTFSNYVLQPLFPTCFPP-ENGLRILAAICLLLLTWVNCSSVRWATRVQDVFTAGKLLALILIIIMGIVQICKG-EYYWLEPANAFEPFQDYDVGLIALAFLQGSFAYGGWNFLNYVTEELVDPYVNLPRAIFISIPLVTFVYVFANIAYVTAMSPQELLAS-NAVAVTFGEKLLG--VMSWIMPISVALSTFGGVNGSLFTSSRLFFAGAREGHLPSLLAMIHVKRCTP----IPALLFTCISTLLMLCT-SDMYTLIN-YVGFINYLFYGVTVAGQIVLRIKQP----DMHRPIKISLVWPVIYLLFWAFLLIFSLYSEP------VVCGIGLAIMLTGVPVYFLGVYWDNKPQCFNTFVDKMTYLGQKFCVVVYPMEEVKKTDESAEGIELKEQTAPLSAEGEETPKSADC---", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9QXW9-1", "uniprot_id": "LAT2_MOUSE", "id": "Q9QXW9-1", "name": "Large neutral amino acids transporter small subunit 2", "aln": "-------------------------MEKGARQRNNTAKNHP--GSDTSPEAEASSGGGGVALKKEIGLVSACGIIVGNIIGSGIFVSPKGVLENAG-SVGLALIVWIVTGIITAVGALCYAELGVTIPKSGGDYSYVKDIFGGLAGFLRLWIAVLVIYPTNQAVIALTFSNYVLQPLFPTCFPP-ESGLRLLAAICLLLLTWVNCSSVRWATRVQDIFTAGKLLALALIIIMGIVQICKG-EFFWLEPKNAFENFQEPDIGLVALAFLQGSFAYGGWNFLNYVTEELVDPYKNLPRAIFISIPLVTFVYVFANIAYVTAMSPQELLAS-NAVAVTFGEKLLG--VMAWIMPISVALSTFGGVNGSLFTSSRLFFAGAREGHLPSVLAMIHVKRCTP----IPALLFTCLSTLLMLVT-SDMYTLIN-YVGFINYLFYGVTVAGQIVLRWKKP----DIPRPIKVSLLFPIIYLLFWAFLLIFSLWSEP------VVCGIGLAIMLTGVPVYFLGVYWQHKPKCFNDFIKSLTLVSQKMCVVVYPQ-EGNSGAEETTDDLEEQHKPIFKPTPVKDPDSEEQP--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9WVR6-1", "uniprot_id": "LAT2_RAT", "id": "Q9WVR6-1", "name": "Large neutral amino acids transporter small subunit 2", "aln": "-------------------------MEKGTRQRNNTAKNHPDRGSDTSPEAEASSGGGGVALKKEIGLVSACGIIVGNIIGSGIFVSPKGVLENAG-SVGLALIVWIVTGVITAVGALCYAELGVTIPKSGGDYSYVKDIFGGLAGFLRLWIAVLVIYPTNQAVIALTFSNYVLQPLFPTCFPP-ESGLRLLAAICLLLLTWVNCSSVRWATRVQDIFTAGKLLALALIIIMGVVQICKG-EFFWLEPKNAFENFQEPDIGLVALAFLQGSFAYGGWNFLNYVTEELVDPYKNLPRAIFISIPLVTFVYVFANIAYVTAMSPQELLAS-NAVAVTFGEKLLG--VMAWIMPISVALSTFGGVNGSLFTSSRLFFAGAREGHLPSVLAMIHVKRCTP----IPALLFTCLSTLLMLVT-SDMYTLIN-YVGFINYLFYGVTVAGQIVLRWKKP----DIPRPIKISLLFPIIYLLFWAFLLIFSLWSEP------VVCGIGLAIMLTGVPVYFLGVYWQHKPKCFNDFIESLTLVSQKMCVVVYPQ-EGDSGTEETIDDVEEQHKPIFQPTPVKDPDSEEQP--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9UHI5-1", "uniprot_id": "LAT2_HUMAN", "id": "Q9UHI5-1", "name": "Large neutral amino acids transporter small subunit 2", "aln": "-------------------------MEEGARHRNNTEKKHPG-GGESDASPEAGSGGGGVALKKEIGLVSACGIIVGNIIGSGIFVSPKGVLENAG-SVGLALIVWIVTGFITVVGALCYAELGVTIPKSGGDYSYVKDIFGGLAGFLRLWIAVLVIYPTNQAVIALTFSNYVLQPLFPTCFPP-ESGLRLLAAICLLLLTWVNCSSVRWATRVQDIFTAGKLLALALIIIMGIVQICKG-EYFWLEPKNAFENFQEPDIGLVALAFLQGSFAYGGWNFLNYVTEELVDPYKNLPRAIFISIPLVTFVYVFANVAYVTAMSPQELLAS-NAVAVTFGEKLLG--VMAWIMPISVALSTFGGVNGSLFTSSRLFFAGAREGHLPSVLAMIHVKRCTP----IPALLFTCISTLLMLVT-SDMYTLIN-YVGFINYLFYGVTVAGQIVLRWKKP----DIPRPIKINLLFPIIYLLFWAFLLVFSLWSEP------VVCGIGLAIMLTGVPVYFLGVYWQHKPKCFSDFIELLTLVSQKMCVVVYPEVERGSGTEEANEDMEEQQQPMYQPTPTKDKDVAGQPQP", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VKC2-1", "uniprot_id": "Q9VKC2_DROME", "id": "Q9VKC2-1", "name": "", "aln": "-------------------------MTDRYANGVTTSLVEPTNGCAAPGNPNPADGEEKIVLKRKLTLINGVAIIVGTIIGSGIFIAPTGVFIYTE-SVGSSLLIWLTCGILSTIGALCYAELGTCITRSGGDYAYLLVSFGPLVGFLRLWIALLIIRPTTQTIVALSFAHYAVKPFFPECDPP-QNAVKLLAAICLTLLTTINCLSVKVSMKVQDVFTVGKLLALIMIILSGLYYMATG-ELENFR--NPWEGIYTARN--IGYAFYSGLFAFGGWNYLNFVTEELQDPYKNLPRAIWIAMPLVTSIYVLVNLAYFAVVNKPEMLSS-LAVAVTFGNRVFG--PLAFMVPIFVALSTFGGVNGVLFTSARLFATGAQEGHLPKFFQLFHVKQQTP----IPSLIFTCLMSLLMLLT-DNVYQLIN-YFSSVLWLSVVASIAGMLWLRHKRP----DLPRPIKVHLALPITFMVSCVTLVLLPNLEEP------QNLLIGIGITLAGIPFYYAFIARKKKPKCYG----RLSNSVVEICRAIFNTTIIES-NEAIN---------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P50276-1", "uniprot_id": "MUP1_YEAST", "id": "P50276-1", "name": "High-affinity methionine permease", "aln": "-----MSEGRTFLSQLNVFNKENYQFSSSTTKKEVSNSTVDADNGASDFEAGQQFATELDQGEKQLGILSCIGLICNRMLGTGVFAVSSTIYTLCG-SVGLALIMWAVGAIIAISGLYVYMEFGTAIPKNGGEKNYLEAIFRKPKFFITCMYAAYIFFLGWAAGNSINTAIMFLTAADTEVTKWNQRGIGVAVVFFAFLINSLNVKIGLYLQNILGIFKIGIVLFISITGWVALGGGLKD-GYQSHNFRNAFEGTETATAYGIVNALYSVIWSFVGYSNVNYALGEVKNPVRTLKIAGPTSMVFLAIIYIFVNIAYFAVVPKDKLISSKLILAADFFDIVFGG-QAKRAAAALVGLSALGNVLSVIFSQGRIIQQLGREGVLPFSNFFASSKPFNSPMVGLFQHFIVCTVTILAPPP-GDAYLLVQNLISYPMNIINFAISAGLLWIYWQRRQGKIEWNPPIKAGVFVTGFFTLSNLYLIIAPYVPPSNGESVYSSMPYWIHCVIAWGIFFFGGVYYVVWAQLLPRWGHYKLVSKDVLGEDGFWRVKIAKVYDDTIGDVDTQEDGVIETNIIEHYKSEQEKSL", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P38734-1", "uniprot_id": "MUP3_YEAST", "id": "P38734-1", "name": "Low-affinity methionine permease", "aln": "MEPLLFNSGKANPSQDVFIDVEVGDITTKYGSTNTGSFSSMDTVEAQAIKAETARFMEVPQG-RHLGVFSTVVLFVSRIMGSGIFAVPSVILLNTGGNKLIYFAIWVFSAAIAFAGLYLFLEFGSWIPKSGGRKNFLERSFERPRLLISVVFSCYSVLTGYALTGSIVFGKYVLSAFGVTDDSW-SKYVSISFIIFAVLIHGVSVRHGVFIQNALGGLKLIMIVLMCFAGLYTLFFYKSTGQVAWDLPVTQVEKDSLLSVSSIATAFISSFFCFSGWDTVHTVTSEIKNPVKTLKVSGPLSLIICFVCYTMMNVAYLKVLTYEEIVSAGPLVGSVLFTKLFGPRVGGKFIAFSIAISAASNILVVIYSISRVNQEIFKEGYLPFSIHMSKNWPFDAPLPSISLCGFITIAWILILPKEGESFNYLVSMDGYGNQFFLLLVAIGLFIWRFKHK----NEVPEIRASTFGVLAIITLSLYMLMAPFFADPSLN---RVGFLPPYQIMSLLVIVACFFFWLVKFVLLPKFFHYKLLPKITYLHDGLIVTEWVKKPCLC----------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : :.: :.. :. . ::*:*:* .. : . : :* . :: * : *:* *.:.** :: * :: : . :: . : . . : : . *: :. . . :. :: : : : . . : *. . :.: *:. :: . *: :* .* : :: : * *:**. .: ::::: :. : ::* . :.:*: ..: ::: .*: :** ** : . : : :* .: : : . : * : :. : *: ::: . . :: . . . ", "identical_positions": 31, "similar_positions": 129, "identity": "5.32%" }, { "cls_id": "homologset.agr.MGI:1355324", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9JLM9-1", "uniprot_id": "GRB14_MOUSE", "id": "Q9JLM9-1", "name": "Growth factor receptor-bound protein 14", "aln": "MTTSLQDGQSAAGRAGAQDSPLAVQVCRVAQGKGDAQDPAQVPGLHA--LSPASDATLRGAIDRRKMKDLDVLEKPPIPNPFPELCCSPLTSVLSAGLFPRANSRKKQVIKVYSEDETSRALEVPSDITARDVCQLLILKNHYVDDNSWTLFEHLSHIGLERTVEDHELPTEVLSHWGVEEDNKLYLRKNYAKYEFFKNPMYFFPEHMVSFAAEMNGDRSPTQILQVFLSSSTYPEIHGFLHAKEQGKKSWKKAYFFLRRSGLYFSTKGTSKEPRHLQLFSEFSTSHVYMSLAGKKKHGAPTPYGFCLKPNKAGGPRDLKMLCAEEEQSRTCWVTAIRLLKDGMQLYQNYMHPYQGRSACNSQSMSPMRSVSENSLVAMDFSGEKSRVIDNPTEALSVAVEEGLAWRKKGCLRLGNHGSPSAPSQSSAVNMALHRSQPWFHHRISRDEAQRLIIRQGPVDGVFLVRDSQSNPRTFVLSMSHGQKIKHYQIIPVEDDGELFHTLDDGHTKFTDLIQLVEFYQLNRGVLPCKLKHYCARMAV", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O88900-1", "uniprot_id": "GRB14_RAT", "id": "O88900-1", "name": "Growth factor receptor-bound protein 14", "aln": "MTTSLQDGQSAAGRAGAQDSPLAVQVCRVAQGKGDAQDPAQVPGLHA--LSPASDATRRGAMDRRKAKDLEVQETPSIPNPFPELCCSPLTSVLSAGLFPRSNSRKKQVIKVYSEDETSRALEVPSDVTARDVCQLLILKNHYVDDNSWTLFEHLSHTGVERTVEDHELLTEVLSHWVMEEDNKLYLRKNYAKYEFFKNPMYFFPEHMVSFATEMNGDRSLTQIPQVFLSSNTYPEIHGFLHAKEQGKKSWKKAYFFLRRSGLYFSTKGTSKEPRHLQFFSEFSTSNVYMSLAGKKKHGAPTPYGFCFKPTKAGGPRDLKMLCAEEDQSRMCWVTAIRLLKYGMQLYQNYMHPSQARSACSSQSVSPMRSVSENSLVAMDFSGQKTRVIDNPTEALSVAVEEGLAWRKKGCLRLGNHGSPTAPSQSSAVNMALHRSQPWFHHRISRDEAQQLITRQGPVDGVFLVRDSQSNPRTFVLSMSHGQKIKHFQIIPVEDDGEVFHTLDDGHTKFTDLIQLVEFYQLNKGVLPCKLKHYCARMAV", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q14449-1", "uniprot_id": "GRB14_HUMAN", "id": "Q14449-1", "name": "Growth factor receptor-bound protein 14", "aln": "MTTSLQDGQSAASRAAARDSPLAAQVCGAAQGRGDAHDLAPAPWLHARALLPLPDGTRGCAADRRKKKDLDVPEMPSIPNPFPELCCSPFTSVLSADLFPKANSRKKQVIKVYSEDETSRALDVPSDITARDVCQLLILKNHYIDDHSWTLFEHLPHIGVERTIEDHELVIEVLSNWGIEEENKLYFRKNYAKYEFFKNPMYFFPEHMVSFATETNGEISPTQILQMFLSSSTYPEIHGFLHAKEQGKKSWKKIYFFLRRSGLYFSTKGTSKEPRHLQFFSEFGNSDIYVSLAGKKKHGAPTNYGFCFKPNKAGGPRDLKMLCAEEEQSRTCWVTAIRLLKYGMQLYQNYMHPYQGRSGCSSQSISPMRSISENSLVAMDFSGQKSRVIENPTEALSVAVEEGLAWRKKGCLRLGTHGSPTASSQSSATNMAIHRSQPWFHHKISRDEAQRLIIQQGLVDGVFLVRDSQSNPKTFVLSMSHGQKIKHFQIIPVEDDGEMFHTLDDGHTRFTDLIQLVEFYQLNKGVLPCKLKHYCARIAL", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "************.**.*:*****.*** .***:***:* * .* *** * * .*.* * **** ***:* * *.************:******.***::********************:****:***************:**:********.* *:***:***** ****:* :**:****:*************************:* **: * *** *:****.********************* ************************:****..*.:*:************ ****:**.***************:*** ********** *********** *.**.*.***:*****:************:*:***:*************************.****:*.*****.***:*********:*******:** :** **************:**************:**********:*********:**************:*************:*:", "identical_positions": 447, "similar_positions": 63, "identity": "82.78%" }, { "cls_id": "homologset.agr.MGI:1355326", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9WTV0-1", "uniprot_id": "SEC12_RAT", "id": "Q9WTV0-1", "name": "Guanine nucleotide-exchange factor SEC12", "aln": "---MGRRRGVELYRAPFPLYALRIDPKTGLLIAAGGGGAAKTGIKNGVHFLQLEQISGCLSASLLHSHDTETRATMNLALAG----DILAAGQDAQCQLLRFQIHQQKGSKAEKSGS--------KEQGPRQRKGAAPAEKKSGAEVHPEG----------------VELKVKNLEAVQTDFST--EPLQKVVCFNHDNTLLATGGSDGHVRVWKVPSLEKVLEFKAHEGEIGDLALGPDGKLVT-VGWDFKASVWQKDQLVTQLQWQENGPTSSNTPYRYQACRFGQVPDQPGGLRLFTVQIPHKRLRQPPPCYLTAWDSSTFLPLQTRSCGHEVISCLTVSESGTFLGLGTVTG-SVAIYIAFSLQRLYYVKEAHGIVVTDVTFLPEKGC-GPKLLGPHETALFSVAVDSRCQLHLLPSRRSVPVWLLLLLCVGLIIVTILLLQSAFPGFL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9WUQ2-1", "uniprot_id": "SEC12_MOUSE", "id": "Q9WUQ2-1", "name": "Guanine nucleotide-exchange factor SEC12", "aln": "---MGRRRGVELYRAPFPLYALRIDPKTGLLIAAGGGGAAKTGIKNGVHFLQLELINGCLSASLLHSHDTETRATMNLALAG----DILAAGQDAQCQLLRFQVHQQKGSKAEKSGS--------KEQGPRQRKGAPPAEKKSGAQVHPEG----------------VELKVKNLEAVQTDFSN--EPLQKVVCFNHDNTLLATGGTDGHVRVWKVPSLEKVLEFKAHEGEIGDLTLGPDGKLVT-VGWDFKASVWQKDQLVTQLQWQENGPASSNTPYRYQACRFGQVPDQLGGLRLFTVQIPHKRLRQPPPCYLTAWDSSTFLPLRTRSCGHEVISCLSVSDSGTFLGLGTVTG-SVAIYIAFSLQRLYYVKEAHGIVVTDVTFLPEKGC-GPKLLGPHETALFSVAVDSRCQLHLLPSRRSVPVWLLLLLCVGLIIVTILLLQTAFPGFL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9HCU5-1", "uniprot_id": "SEC12_HUMAN", "id": "Q9HCU5-1", "name": "Guanine nucleotide-exchange factor SEC12", "aln": "---MGRRRAPELYRAPFPLYALQVDPSTGLLIAAGGGGAAKTGIKNGVHFLQLELINGRLSASLLHSHDTETRATMNLALAG----DILAAGQDAHCQLLRFQAHQQQGNKAEKAGS--------KEQGPRQRKGAAPAEKKCGAETQHEG----------------LELRVENLQAVQTDFSS--DPLQKVVCFNHDNTLLATGGTDGYVRVWKVPSLEKVLEFKAHEGEIEDLALGPDGKLVT-VGRDLKASVWQKDQLVTQLHWQENGPTFSSTPYRYQACRFGQVPDQPAGLRLFTVQIPHKRLRQPPPCYLTAWDGSNFLPLRTKSCGHEVVSCLDVSESGTFLGLGTVTG-SVAIYIAFSLQCLYYVREAHGIVVTDVAFLPEKGR-GPELLGSHETALFSVAVDSRCQLHLLPSRRSVPVWLLLLLCVGLIIVTILLLQSAFPGFL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VMH4-1", "uniprot_id": "Q9VMH4_DROME", "id": "Q9VMH4-1", "name": "Prolactin regulatory element-binding protein", "aln": "MAHTRRPSDGLLARVNFPLYAVDMLTSR-HILVAGGGGSSKTGVANGFEIYELYHNGSHFCAEEVLRHETGANVVMNFAVRNGGRRGYLCAGQEAHCQMYYVQPRVQSEEDGNGNGVGVGDGKPAPEERPHENGNVRQRNAHSGVEPVANGHRPPLSTADILRQFRRLHFDIQAADVIQTDFLKGAEPLQRVVRISGNGRLMATGGTDGKLRVWTFPQMTLAAELAAHSKEIDDLDFSPDSKLIASISKDAQGLVW--DLASGQLQHKLQWKTPEGAKYLFKRCRYGTVEAQKDNYRLFTIANPLGKVGKQR-GFLQHWDCASG-QLRQAVAIDESLSSLAVRDDGRFVAVGTMFSGSVSMYIAFSLQRVLHIPHAHSMFVTGLQFLPITNEEGPPISSDTEAAVLSISVDNKVCIHSLSQRRTIPAWIAIVFLIVMIFAVFVLCS--YIGI-", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * * *. *****: : .. ::.*****::***: **..: :* .. :.*. : *:* :...**:*: . . *.***:*:**: .* : *. ...: * *: *::. .. : :.*.: :* :.: :: :.:**** . :***:** :. :. *:****:** :***..*.: . *: **. ** ** :.**.**:: :. * :. ** * **: : : : ..: * :: **:* * * . ****: * :: : :* ** :. *: . .* :*.* * :.* *:.:**: . **::******* : :: .**.:.**.: *** .. ** : . *:*::*::**.: :* *..**::*.*: ::: : :*:..::* . : *: ", "identical_positions": 131, "similar_positions": 159, "identity": "28.92%" }, { "cls_id": "homologset.agr.MGI:1355328", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q66HD3-1", "uniprot_id": "NASP_RAT", "id": "Q66HD3-1", "name": "Nuclear autoantigenic sperm protein", "aln": "------------MATESTATAAIAAELVSADKVED-APAPSTSADKMESLDVDS---EAKKLLGLGQKHLVMGDIPAAVNAFQEAASLLGKKYGETANECGEAFFFYGKSLLELARMENGVLGNALEGVHVEEEEGEKTEDESLVENNDNVDEEAREELREQVYDAMGEKE-AKKAEGQSLTKPETDKEQESEVEKGGREDMDISEPAEKLQEKVESTSKQLTESSEEAKEAAIP-GLNEDEVTSGKTEQESLCTEEGKSISGVYVQNKEFREAVPQEEGEEMISLEKKPKETSEDQTIGAPEKQDTLMKVVEIEAE-IDSEVKSVDVGGEEPKDQGAISESELGKAVLMQLSGQDV-----------EVSPVVAAEAGSEVSEKPGQEITVLPNNGPVVGQSSAGDQTPSEPQNSAERLSETKDGASVEE-VKAELVPEQEEAMPPVEESEAAGDGVETKVAQRATEKAPEDKFKIAANEETQERDEQMKEGEETEGSEEEDKENDKAEETTNESVLEKKTLQENEEEEIGNLELAWDMLDLAKIIFKRQETKEAQLYAAQAHLKLGEVSVESENYIQAVEEFQACLSLQEQYLEAHDRLLAETHYQLGLAYGYNSQYDEAVAQFGKSIDVIEKRMAVLLEQMKEAEG--SFTEYEKEIEELKELLPEIREKIEDAKESQRSGNVAELALKATLVESSTSGFTPSGAGASVSMIASR---KPTDGASSSNCVTDISHLVRKKRKPEEESPRKD-DAKKAKPEPEVNGGSGDAVSSGNEVSENMEAEAENQAESQTTAEGTVDSAATVKSTAC", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q99MD9-1", "uniprot_id": "NASP_MOUSE", "id": "Q99MD9-1", "name": "Nuclear autoantigenic sperm protein", "aln": "------------MATESTAAAAIAAELVSADKIED-APAPSTSADKMESLDVDS---EAKKLLGLGQKHLVMGDIPAAVNAFQEAASLLGKKYGETANECGEAFFFYGKSLLELARMENGVLGNALEGVHVEEEEGEKTEDESLVENNDNVDEEAREELREQVYDAMGEKE-AKKAEGKSLTKPETDKEQESEVEKGGREDMDISEPEEKLQETVEPTSKQLTESSEEAKEAAIP-GLNEDEVASGKTEQESLCTEKGKSISGAYVQNKEFRETV--EEGEEIISLEKKPKETSEDQPIRAAEKQGTLMKVVEIEAE-IDPQVKSADVGGEEPKDQVATSESELGKAVLMELSGQDV-----------EASPVVAAEAGAEVSEKPGQEITVIPNNGPVVGQSTVGDQTPSEPQTSAERLTETKDGSSVEE-VKAELVPEQEEAMLPVEESEAAGDGVETKVAQKATEKAPEDKFKIAANEETPERDEQMKEGEETEGSEEEDRENDKAEETPNESVLEKKSLQENEEEEIGNLELAWDMLDLAKIIFKRQETKEAQLYAAQAHLKLGEVSVESENYIQAVEEFQACLSLQEQYLEAHDRLLAETHYQLGLAYGYNSQYDEAVAQFGKSIDVIEKRMAVLHEQMKEAEG--SFTEYEKEIEELKELLPEIREKIEDAKESQRSGNVAELALKATLVESSTSGFTPSGAGASVSMIASR---KPTDGASSSNCVTDISHLVRKKRKPEEESPRKD-DAKKAKQEPEVNGGSGDAVSSGKEVSENMEAEAENQAESQT-AEGTVESAATIKSTAC", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P49321-1", "uniprot_id": "NASP_HUMAN", "id": "P49321-1", "name": "Nuclear autoantigenic sperm protein", "aln": "------------MAMESTATAAVAAELVSADKIED-VPAPSTSADKVESLDVDS---EAKKLLGLGQKHLVMGDIPAAVNAFQEAASLLGKKYGETANECGEAFFFYGKSLLELARMENGVLGNALEGVHVEEEEGEKTEDESLVENNDNIDEEAREELREQVYDAMGEKEEAKKTEDKSLAKPETDKEQDSEMEKGGREDMDISKSAEEPQEKVDLTLDWLTETSEEAKGGAAPEGPNEAEVTSGKPEQEVPDAEEEKSVSGTDVQEECREKGGQEKQGEVIVSIEEKPKEVSEEQPVVTLEKQGT---AVEVEAESLDPTVKPVDVGGDEPEEKVVTSENEAGKAVLEQLVGQEVPPAEESPEVTTEAAEASAVEAGSEVSEKPGQEAPVLPKDGAVNGPSVVGDQTPIEPQTSIERLTETKDGSGLEEKVRAKLVPSQEETKLSVEESEAAGDGVDTKVAQGATEKSPEDKVQIAANEETQEREEQMKEGEETEGSEEDDKENDKTEEMPNDSVLENKSLQENEEEEIGNLELAWDMLDLAKIIFKRQETKEAQLYAAQAHLKLGEVSVESENYVQAVEEFQSCLNLQEQYLEAHDRLLAETHYQLGLAYGYNSQYDEAVAQFSKSIEVIENRMAVLNEQVKEAEG--SSAEYKKEIEELKELLPEIREKIEDAKESQRSGNVAELALKATLVESSTSGFTPGGGGSSVSMIASR---KPTDGASSSNCVTDISHLVRKKRKPEEESPRKD-DAKKAKQEPEVNGGSGDAVPSGNEVSENMEEEAENQAESRAAVEGTVEAGATVESTAC", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F1QNE0-1", "uniprot_id": "F1QNE0_DANRE", "id": "F1QNE0-1", "name": "", "aln": "------------MPEETGATS-------TAERMEE-KPCSSSTGD--SSVDVAE---EAKKLIGTGSRHLVMGDVVSAVSVFQEACAMLAEKYGDTADECGEAFFFCGKALLELARMENTVLGNALEGVPEESSEEGEKQDDSKIESADNLDEKTRDELRAQVYDAMSEDN----------TRSEVEKEECGEGERNNKE-------EDEKQVKVD-------EAPKEADTASKTEKPTEDEAKPAE-NQEKMAVDEEKPAE----------------KQEKMAVDEAKPAENEK---------------LAKDEAK---------------PEEKLAEEETKQAED---------------------EAKPAENEERPAEDKAKP----------------------------ASIEKCGNEDEKSKGED--------------------EDASTNKDVTVSNGIAEKNKDE--SVEEKKGSEDTEEPMEEDGGDDDGDEDEDDDEDAEGDAKD--------KESEEDEVGNLQLAWEMLEVAKVIYKRKDDKEDQLMAAQIHLKLAEVGVESGNYSQALEDFNECLTLQLKHLPSHSRLLAETHYQLGTTYSYTTQYNQAIEHFSNSIKVIESRLAMLQEVIDKAEGEDSAKEEKGEFEELKQLLPEIKEKIEDAKESQRTAAAASEAIHQTLAGASTSSAFPTENGGPSSSTASQIAVRPADGASSSKSASDISHLVRKKRKPDEESPKKDSDAKKTKQDTSVNG-SDDSAHNGNGVQEKMEQEPAN--------------SSSVETSA-", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9I7K6-1", "uniprot_id": "NASP_DROME", "id": "Q9I7K6-1", "name": "Nuclear autoantigenic sperm protein homolog", "aln": "MSAEAEAIVTTATADVSSPSKTVAVEPVAADTTPDNAPAVSTEGSGKAEQERAEKILKGKELFSQGSRNFLVKSYDEAADELSQVCQLYEEVYGELADELGQPLLLYAKALIAMALDENKVIDVPDEAADDDDEDVDDDEEESAEDGAAKKEEKK--------------------------------------------------------------------DTKEAANGASSSNGKELDTIKEGSDEADSTGEAEQAQSD---------------EKPSKKVPTGVDEVSSS-------------------------------------------------------------------------------------------------------------------------------NGGGGAAVND----------------------------------------------DERPSTSNGEVTASCSNGAAPAVEEE--------------------PEEEEGVSGSLQLAWEILEAAAQIFSRQG-LSGLPYLAEVQTELANIEFENGILEAAREDYEKALKIHGELPTRNRRALAELHYKIGLTYLMQQLNKEGATALRQSSVLIEEEIAEIKGKDEPSER------DRNNMLDLEETKQEILAKIQEIEEMQAQTIAEVRAALDSYIKPMSSGDAAAASSSSSS---------SANGAASSSSSSSKGAAAASSSTISSSSAKPTDITHLIKRKK-----PEDPSSEAEALCSPAKRAAV------------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . : .: :*: : *. *: .. . : . :.*:*:. *.::::: . *.. :.:.. : : **: *:* *:.::: .*:*: :* ** *:. . *.. :..: . :::* :. : :*: :: : *. .: . .. : : : . : . . . . : : :: . : : : . . . *:: *.** *.*:***::*: * *:.*: . *: : :*.:: .*. * *::: .*.:: : : * *** **::* :* .:. : :* :**..:* : . :* . :: :*:: ** **:: :* * . * : . :*. . ... * .::**:**.. :. . . .. . ...*.: :: * . . *. ..: : . : . ", "identical_positions": 71, "similar_positions": 185, "identity": "8.73%" }, { "cls_id": "homologset.agr.MGI:1355329", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "F1LP90-1", "uniprot_id": "MINK1_RAT", "id": "F1LP90-1", "name": "Misshapen-like kinase 1", "aln": "-----MGDPAPAR--QSDFIFLVALRDPAGIFELVEVVGNGTYGQVYKGRHVKTGQLAAIKVMDVTEDEEEEIKQEINMLKKYSHHRNIATYYGAFIKKSPPGNDDQLWLVMEFCGAGSVTDLVKNTKGNALKEDCIAYICREILRGLAHLHAHKVIHRDIKGQNVLLTENAEVKLVDFGVSAQLDRTVGRRNTFIGTPYWMAPEVIACDENPDATYDYRSDIWSLGITAIEMAEGAPPLCDMHPMRALFLIPRNPPPRLKSKKWSKKFTDFIDTCLIKTYLSRPPTEQLLKFPFIRDQPTERQVRIQLKDHIDRSRKKRGEKEETEYEYSGSEEEDDSHGEEGEPSSIMNVPGESTLRREFLRLQQ-----ENKSNSEALKQQQQLQQQQQRDPEAHIKHLLHQRQRRIEEQKEERRRVEEQQRREREQ-RKLQEKEQ-----QRRLEDMQALRREEERRQAEREQEYKRKQLEE-QRQSERLQRQLQQEHAYLN-----------------------SQKQQQQQQQQQ-QQQQQQQILP---------GDRKP-----------LYHYGRGINPADKPAWAREVEERARMNKQQNSPLAKTKPSSAGPEPPIPQAS-PSPPGPLSQTPPMQRPVEP------QEGPHKSLVAHRVPLKPYAAPVPRSQSLQDQ-PTR-----------NLAAFPASHDPDPAAVPTPTATPSARGAVIRQNSDPTSEGPGPSPNPP-----SWVR-PDNEAPPKVPQRTSSIATALNTSGAGGSRPAQAVRARPRSNSAWQIYLQRRAERGTPKPPGPPAQPPGPPNTSSNPDLRRSDPGWERSDSVLPASHGHLPQAGSLERNRNRVGASTKLDSSP---VLSPGNKAKPEDHR--SRPGRPA------------------DFVLLKERT--------LDEAPKPPKKAMDYSSSSEEVESSEDEEEEGDGEPSEGSRDTPGGRSDGDTDS----------VSTMVVHDVEEVSGTQPS----------YGGGTMVVQRTPEEERSLLLADSNGYTNLPD-------VVQPSHSP--------TENSQGQSPPTKDGGGDYQSRGLVKAPGKSSFTMFVDLGIYQP-GGSGDTIPITALVGGEGGRLDQ-----LQFDVRKGS----------VVNVNPTNTRAHSETPEIRKYKKRFNSEILCAALWGVNLLVGTENGLMLLDRSGQGKVYGLIGRRRFQQMDVLEGLNLLITISGKRNKLRVYYLSWLRNKILHND---PEVEKKQGWTTVGDMEGCGHYRVVKYERIKFLVIALKNSVEVYAWAPKPYHKFMAFKSFADLPHRPLLVDLTVEEGQRLKVIYGSSAGFHAVDVDSGNSYDIYIPVHIQSQITPHAIVFLPNTDGMEMLLCYEDEGVYVNTYGRIIKDVVLQWGEMPTSVAYICSNQIMGWGEKAIEIRSVETGHLDGVFMHKRAQRLKFLCERNDKVFFASVRSGGSSQVYFMTLNRNCIMNW", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9JM52-1", "uniprot_id": "MINK1_MOUSE", "id": "Q9JM52-1", "name": "Misshapen-like kinase 1", "aln": "-----MGDPAPAR--SLDDIDLSALRDPAGIFELVEVVGNGTYGQVYKGRHVKTGQLAAIKVMDVTEDEEEEIKQEINMLKKYSHHRNIATYYGAFIKKSPPGNDDQLWLVMEFCGAGSVTDLVKNTKGNALKEDCIAYICREILRGLAHLHAHKVIHRDIKGQNVLLTENAEVKLVDFGVSAQLDRTVGRRNTFIGTPYWMAPEVIACDENPDATYDYRSDIWSLGITAIEMAEGAPPLCDMHPMRALFLIPRNPPPRLKSKKWSKKFTDFIDTCLIKTYLSRPPTEQLLKFPFIRDQPTERQVRIQLKDHIDRSRKKRGEKEETEYEYSGSEEEDDSHGEEGEPSSIMNVPGESTLRREFLRLQQ-----ENKSNSEALKQQQQLQQQQQRDPEAHIKHLLHQRQRRIEEQKEERRRVEEQQRREREQ-RKLQEKEQ-----QRRLEDMQALRREEERRQAEREQEYKRKQLEE-QRQSERLQRQLQQEHAYLK-----------------------SLQQQQQQQQLQKQQQQQQQILP---------GDRKP-----------LYHYGRGINPADKPAWAREVEERARMNKQQNSPLAKAKPSSAGPEPPISQAS-PSPPGPLSQTPPMQRPVEP------QEGPHKSLVAHRVPLKPYAAPVPRSQSLQDQ-PTR-----------NLAAFPASHDPDPAAVPTPTATPSARGAVIRQNSDPTSEGPGPSPNPP-----SWVR-PDNEAPPKVPQRTSSIATALNTSGAGGSRPAQAVRA-------------------------------------SNPDLRRSDPGWERSDSVLPASHGHLPQAGSLERNRNRVGASTKLDSSP---VLSPGNKAKPEDHR--SRPGRPASYKRAIG----------EDFVLLKERT--------LDEAPKPPKKAMDYSSSSEEVESSEEEEEEGDGEPSEGSRDTPGGRSDGDTDS----------VSTMVVHDVEEISGTQPS----------YGGGTMVVQRTPEEERSLLLADSNGYTNLPD-------VVQPSHSP--------TENSKGQSPPTKDGGSDYQSRGLVKAPGKSSFTMFVDLGIYQP-GGSGDTIPITALVGGEGGRLDQ-----LQFDVRKGS----------VVNVNPTNTRAHSETPEIRKYKKRFNSEILCAALWGVNLLVGTENGLMLLDRSGQGKVYGLIGRRRFQQMDVLEGLNLLITISGKRNKLRVYYLSWLRNKILHND---PEVEKKQGWTTVGDMEGCGHYRVVKYERIKFLVIALKNSVEVYAWAPKPYHKFMAFKSFADLPHRPLLVDLTVEEGQRLKVIYGSSAGFHAVDVDSGNSYDIYIPVHIQSQITPHAIIFLPNTDGMEMLLCYEDEGVYVNTYGRIIKDVVLQWGEMPTSVAYICSNQIMGWGEKAIEIRSVETGHLDGVFMHKRAQRLKFLCERNDKVFFASVRSGGSSQVYFMTLNRNCIMNW", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8N4C8-1", "uniprot_id": "MINK1_HUMAN", "id": "Q8N4C8-1", "name": "Misshapen-like kinase 1", "aln": "-----MGDPAPAR--SLDDIDLSALRDPAGIFELVEVVGNGTYGQVYKGRHVKTGQLAAIKVMDVTEDEEEEIKQEINMLKKYSHHRNIATYYGAFIKKSPPGNDDQLWLVMEFCGAGSVTDLVKNTKGNALKEDCIAYICREILRGLAHLHAHKVIHRDIKGQNVLLTENAEVKLVDFGVSAQLDRTVGRRNTFIGTPYWMAPEVIACDENPDATYDYRSDIWSLGITAIEMAEGAPPLCDMHPMRALFLIPRNPPPRLKSKKWSKKFIDFIDTCLIKTYLSRPPTEQLLKFPFIRDQPTERQVRIQLKDHIDRSRKKRGEKEETEYEYSGSEEEDDSHGEEGEPSSIMNVPGESTLRREFLRLQQ-----ENKSNSEALKQQQQLQQQQQRDPEAHIKHLLHQRQRRIEEQKEERRRVEEQQRREREQ-RKLQEKEQ-----QRRLEDMQALRREEERRQAEREQEYKRKQLEE-QRQSERLQRQLQQEHAYLK-----------------------SLQQQQQQQQLQ--KQQQQQLLP---------GDRKP-----------LYHYGRGMNPADKPAWAREVEERTRMNKQQNSPLAKSKPGSTGPEPPIPQAS-PGPPGPLSQTPPMQRPVEP------QEGPHKSLVAHRVPLKPYAAPVPRSQSLQDQ-PTR-----------NLAAFPASHDPDP-AIPAPTATPSARGAVIRQNSDPTSEGPGPSPNPP-----AWVR-PDNEAPPKVPQRTSSIATALNTSGAGGSRPAQAVRARPRSNSAWQIYLQRRAERGTPKPPGPPAQPPGPPNASSNPDLRRSDPGWERSDSVLPASHGHLPQAGSLERNR--VGVSSKPDSSP---VLSPGNKAKPDDHR--SRPGRPA------------------DFVLLKERT--------LDEAPRPPKKAMDYSSSSEEVESSEDDEEEGEGGPAEGSRDTPGGRSDGDTDS----------VSTMVVHDVEEITGTQPP----------YGGGTMVVQRTPEEERNLLHADSNGYTNLPD-------VVQPSHSP--------TENSKGQSPPSKDGSGDYQSRGLVKAPGKSSFTMFVDLGIYQP-GGSGDSIPITALVGGEGTRLDQ-----LQYDVRKGS----------VVNVNPTNTRAHSETPEIRKYKKRFNSEILCAALWGVNLLVGTENGLMLLDRSGQGKVYGLIGRRRFQQMDVLEGLNLLITISGKRNKLRVYYLSWLRNKILHND---PEVEKKQGWTTVGDMEGCGHYRVVKYERIKFLVIALKSSVEVYAWAPKPYHKFMAFKSFADLPHRPLLVDLTVEEGQRLKVIYGSSAGFHAVDVDSGNSYDIYIPVHIQSQITPHAIIFLPNTDGMEMLLCYEDEGVYVNTYGRIIKDVVLQWGEMPTSVAYICSNQIMGWGEKAIEIRSVETGHLDGVFMHKRAQRLKFLCERNDKVFFASVRSGGSSQVYFMTLNRNCIMNW", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9QDG2-1", "uniprot_id": "A0A8M9QDG2_DANRE", "id": "A0A8M9QDG2-1", "name": "non-specific serine/threonine protein kinase", "aln": "-----MSENAPTR--SLDDIDLAALRDPAGIFELVEVVGNGTYGQVYKGRHVKTGQLAAIKVMDVTEEEEEEIKAEINMLKKYSHHRNIATYYGAFVKKSPPGHDDQLWLVMEFCGAGSVTDLVKNTKGNSLKEDWIAYICREILRGLSHLHAHKVIHRDIKGQNVLLTENAEVKLVDFGVSAQLDRTVGRRNTFIGTPYWMAPEVIACDENPDSTYDYRSDIWSLGITAIEMAEGAPPLCDMHPMRALFLIPRNPPPKLKSKKWSKKFIDFIEGCLVKSYPNRPSTEQLLKHSFIRDQPTERQVRIQLKDHIDRTRKKRGEKEETEYEYSGSDEEDENRGDERESSSILNVPGESTLRRDFLRLQQ-----ENKERSEALKRQQAQLAAQRRDPEEHKRQLLHDRQKRIEEQKEQRRRLEEQQRKEREMVRQQQDKAP-----HRRLDDMR---REEDRRLAEREQEFIRHKLEEEQRQLEILQQQLLQEQALLMLYNKHCSDSSVNEYK------RKQLEEQRQSERLQRQLQQEHAYLVSLQQQQQQ-QDKKPQ----------MYHYSKNLE-NNKPAWAREVEERSKLNRQGSPKICTTVSDTN----IQSRSE-SINQSGAAQTPPMQRPVEP------QGGQGKFQMAHLVPLKPYAAPVPRSQSLCDQ-PTK-----------TMSAFPT-QDPSP----TPTPRPLHSRELVRQNSDPTSETPAPQSRPMRDDRGPWIRLPEIEQPPKIPQRTASIATALNTNLSSGIR--HPVRA-------------------------------------SNPDLSRNE-RWERGDSMSIMSN--LPQTGSLERHR--ILSSSKMDSSP---TLSHDGRHKPGESRTSSRPSRPASYKRAIG----------EDHGLYSKER--------AEEQPRPPVKANDYSSSSESSESSE-ESESGEGAEEESPTDRP---RDADSDS----------VNTMVVHEEEEGEGGEEERAGG------YGDQTMLVQRTPEKR------SHNGYTNLPD-------VVQPSHSP--------TDSAS-HSSPGKDSTYDYQSRGLVKASGKSSFTTFVDLGMYQPSGGSGDNIS----VGGLGSRFEQ-----LKLEVRKGS----------MVNVNPTNTRPVSDTPEIRKYKKRFNSEILCAALWGVNLLVGTENGLKLLDRSGQGKVYPLINSRRFQQMDVLEGLNLLITISGKKNKVRVYYLAWLRNKILHND---PEVEKKQGWTTVGEMEGCVHYKVVKYERIKFLVIALKNAVEVYAWAPKPYHKFMAFKSFGDLPHRPVLVDLTVEEGQRLKVIYGSLAGFHAIDVDSGNNYDIYIPVHIQSQITPHAIVFLPNSDGMEMLLCYEDEGVYVNTYGRIIKDVVLQWGEMPTSVAHICSNQIMGWGEKAIEIRSVETGHLDGVFMHKRAQRLKFLCERNDKVFFASVRSGGSSQVYFMTLNRNCIMNW", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9W002-1", "uniprot_id": "Q9W002_DROME", "id": "Q9W002-1", "name": "non-specific serine/threonine protein kinase", "aln": "MAHQQQQQLAPSVNCSLDDIDLTALKDPAGIFELIEVVGNGTYGQVYKGRHTKTGQLAAIKVMDVTEDEEEEIKLEINVLKKYSNHRNIATYYGAFIKKSPPGKDDQLWLVMEYCGAGSVTDLVKSTKGQSLKEEWIAYICREILRGLSYLHSNKVIHRDIKGQNVLLTDNAEVKLVDFGVSAQLDRTIGRRNTFIGTPYWMAPEVIACDENPDATYDNRSDLWSLGITALEMAESQPPLCDLHPMRALFLIPRNSPPRLKSKKWSKKFHGFIDTVLVKDYHQRPYTENLLKHGFIKDQPTDRQVRIQLKDHIDRCKKRKQEKEREDYRYSGSDNDDDEPQLAGEHSSIVQAPGGDTLRRNFQQIQEGRLAAEQQQQHHLMAQAQAQAAAAHAAAQAQAQLQQQQQQAAAAAAAAAHAAQQAQQAAQQAQAQQPQANRQPKPPSRQQVEEPGPPARPPQRLIVVPDPPHANRPLPPTPKCGEPAGQTPQQQQRNSQNNFKPSLPPRRPEPQPQTAAGGQGSQQQAQPEAPPRNNRQSSGLSSSGGSASGGGGSSKPAAALPQQSNNHLGQPVNPLDPLDSSDSDSEPDEPNDRARNDGTLLASDPPKPLPGLGPVSEDANTTTPLSHGSGGPPNRPLPPTPDDDDQAGDRTLIMKRKLEQNINRLQKSASTSQANVTPSRRGDESNLLRDWDFDRFFPKNANGPRGSGRGSPTTTASLSRSSQLSTLKVDTKLQRASVAEAITRPVPR--GYQPLKAEPSASQSIAKEQGSASGSGSGSGSASGSGSGGSTNSPAHKRQDSDSRLPTNFERGFRRENSDFFPLAKRYSAVFSGASASGSTAGSPSAQALQRSSAVYQRNSIYSSSISSKSKENDVPGAPGAAAAGTATASAKPGPAAATTTATKGAAPKTSKSLANFHFLRPRREKTESVIVLQNAAVRAQRLQQLQQQQQQQQLQQQQQQQNRGGGGGGGGGGGGGGSSGVGADGTGLGTPGTRTSSVLPDLLSQASPATPPRHDKSSSEEYQAAISSSVHSTPSKS--FIASSGSGGLGLGGGTVVGGVIISSNHSPQSTISLASSSSNSRQNSPKNSISKTRSSSSITNLLHKSASSSSANLHHLTP-CSSTSSASISNPLPPHAYALQQKQRSFLTFGFGAGGSGPSRRESHVNVNVTPTSHEAANDTPEIRKYKKRFNSEILCAALWGVNLLIGTENGLMLLDRSGQGKVYQLISRRRFQQMEVLEGQNILVTISGKKNRVRVYYLSWLKSKILRTDGLSDQVERRNGWINVGDLQGAVHFKIVKYERIKFLVIALKDSIEIYAWAPKPYHKFMAFKNFGELEHRPLLVDLTIEDQSRLKVIYGSAEGFHAVDLDSAEVYDIYLPKHTQGAIIPHCIVALPNSNGMQLLLCYDNEGVYVNTVGRVSKNIVLQWGEMPTSVAYIGTGQIMGWGNKAIEIRSVESGHLDGVFMHKKAQRLKFLCERNDKVFFSSAKGASSCQIYFMTLNKPGMANW", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : **: . * * * **:********:****************.***************:****** ***:*****:***********:******:*********:***********.***::***: ************::**::***************:******************:*************************:*** ***:*******:****. *****:************.**:********** .**: *:* * .** **:***. **:****:************* :*:: ***. :*.****:::*:. * ***::.** .****:* ::*: *::.. . : : * : .: : : :::* : : ** :: :: * : :::::: * :* . : . .: * : * : *:: ::* * : :*. . ** : : . :: :.. * :* :: .. :.. . . .. . .. * :**: * * * . : : : : . * * : *:: : * . : .* :. . * * . : . . * : *. : ***. .: ..* . : . ..* . * .* :* : *: ..* . . . . ::*. .* :. : . :: . . : : ....:. : .: :.:.. * . . .. . ..::: . .: . : *: **.: . .* .* . ::...*** :.. . :..* :. .* .:.: **: : .:* * .* .. . : . ::* * . *. ***.**. .. .:**************************:****** *********** **. ******:**** *:*:*****:*::*****:**:.***:.* :**:::** .**:::*. *:::**************.::*:***************.*.:* ***:*****:*: .******** ****:*:**.: ****:* * *. * **.*: ***::**::****::******* **: *::************:* :.******:*********:**********:****************:*.:...*.*:******: : **", "identical_positions": 576, "similar_positions": 327, "identity": "38.17%" }, { "cls_id": "homologset.agr.MGI:1355330", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O08651-1", "uniprot_id": "SERA_RAT", "id": "O08651-1", "name": "D-3-phosphoglycerate dehydrogenase", "aln": "----------------------------------------------------MAFANLRKILISDSLDPCCRKILQDGGLQVVE-KQNLSKEELIAELQDCEGLIVRSATKVTADVINAAE-KLQVVGRAGTGVDNVDLEAATRKGVLVMNTPNGNSLSAAELTCGMLMCLARQIPQATASMKDGKWDRKKFMGTELNGKTLGILGLGRIGREVAARMQAFGMKTVGYDPIISPEVAASFGVQQLPLEEIWPLCDFITVHTPLLPSTTGLLNDSTFAQCKKGVRVVNCARGGIVDEGALLRALQSGQCAGAALDVFTEEPPR-------------DRALVDHENVISCPHLGASTKEAQSRCGEEIAVQFVDMVKGKSLTGVVNAQALTSAFSPHTKPWIGLAEALGTLMHAWAGS--PKGTIQVVTQGTSLKNAGTCLSPAVIVGLLREASKQADVNLVNAKLLVKEAGLNVTTSHSPGVPGEQGIGECLLTVALAGAPYQAVGLVQGTTPMLQMLNGAVFRPEVPLRRGQPLLLFRAQPSDPVMLPTMIGLLAEAGVQLLSYQTSKVSDG-DTWHVMGLSSLLPSLDAWKQHVSEAFQFCF", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q61753-1", "uniprot_id": "SERA_MOUSE", "id": "Q61753-1", "name": "D-3-phosphoglycerate dehydrogenase", "aln": "----------------------------------------------------MAFANLRKVLISDSLDPCCRKILQDGGLQVVE-KQNLSKEELIAELQDCEGLIVRSATKVTADVINAAE-KLQVVGRAGTGVDNVDLEAATRKGILVMNTPNGNSLSAAELTCGMIMCLARQIPQATASMKDGKWDRKKFMGTELNGKTLGILGLGRIGREVATRMQSFGMKTVGYDPIISPEVAASFGVQQLPLEEIWPLCDFITVHTPLLPSTTGLLNDSTFAQCKKGVRVVNCARGGIVDEGALLRALQSGQCAGAALDVFTEEPPR-------------DRALVDHENVISCPHLGASTKEAQSRCGEEIAVQFVDMVKGKSLTGVVNAQALTSAFSPHTKPWIGLAEAMGTLMHAWAGS--PKGTIQVVTQGTSLKNAGTCLSPAVIVGLLREASKQADVNLVNAKLLVKEAGLNVTTSHNPGVPGEQGSGECLLTVALAGAPYQAVGLVQGTTPMLQMLNGAVFRPEVPLRRGQPLLVFRAQPSDPGMLPTMIGLLAEAGVQLLSYQTSMVSDG-EPWHVMGLSSLLPSLETWKQHVLEAFQFCF", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O43175-1", "uniprot_id": "SERA_HUMAN", "id": "O43175-1", "name": "D-3-phosphoglycerate dehydrogenase", "aln": "----------------------------------------------------MAFANLRKVLISDSLDPCCRKILQDGGLQVVE-KQNLSKEELIAELQDCEGLIVRSATKVTADVINAAE-KLQVVGRAGTGVDNVDLEAATRKGILVMNTPNGNSLSAAELTCGMIMCLARQIPQATASMKDGKWERKKFMGTELNGKTLGILGLGRIGREVATRMQSFGMKTIGYDPIISPEVSASFGVQQLPLEEIWPLCDFITVHTPLLPSTTGLLNDNTFAQCKKGVRVVNCARGGIVDEGALLRALQSGQCAGAALDVFTEEPPR-------------DRALVDHENVISCPHLGASTKEAQSRCGEEIAVQFVDMVKGKSLTGVVNAQALTSAFSPHTKPWIGLAEALGTLMRAWAGS--PKGTIQVITQGTSLKNAGNCLSPAVIVGLLKEASKQADVNLVNAKLLVKEAGLNVTTSHSPAAPGEQGFGECLLAVALAGAPYQAVGLVQGTTPVLQGLNGAVFRPEVPLRRDLPLLLFRTQTSDPAMLPTMIGLLAEAGVRLLSYQTSLVSDG-ETWHVMGISSLLPSLEAWKQHVTEAFQFHF", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F1QEY8-1", "uniprot_id": "F1QEY8_DANRE", "id": "F1QEY8-1", "name": "D-3-phosphoglycerate dehydrogenase", "aln": "----------------------------------------------------MAPISVKRVLISESVDPCCKSVLQENGIEVTE-KQQMTKEELIAEIRNYDGLIVRSATKVTADVINAGS-SLKIIGRAGTGVDNVDVDAATKRGIIVMNTPSGNTLSAAELTCALVMSLSRHIPQAVISMKDGKWDRKKFMGSELYGKVLGIVGLGRIGKEVATRMQSFGMKTIGYDPITPPEVSASWGVEQMTLDQLWPQCDYITVHTPLMASTTGLLNDASFAKCKKGVKVVNCARGGIIDEAALLRALESGQCGGAGLDVFVEEPPR-------------ERALVNHPNVISCPHLGASTKEAQARCGKDIALQIVDMATGKALVGAVNAQVLASTFSPDSQQWIRLGESMGKVLKACSASTQPCSQLHVTSLGEALKKSTGFLSSAAVVGLLTEAPHNG-PNLVNALPLAKETGITVHTDHKASDERE----ACVMEVSVNGSRYKAVGSVQAGVPVLLELNGSVFRQPVPLTG--HLLFFRANCS-TEFLSSITGVLATAGVELQSFSASSSSSGGEKWYCMGISSLLGDIGALKSLVKDAAQLTV", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VKI8-1", "uniprot_id": "Q9VKI8_DROME", "id": "Q9VKI8-1", "name": "D-3-phosphoglycerate dehydrogenase", "aln": "-----------------------------------------------------MPLNIRKVLVCDAVDKSCVELLEQHGIKVTY-KLKLPVEELCQEVKNFDAAIVRSDTKITAEVLAAGSGSLKVVGRAGAGVDNIDVPAATAQNVVVLNTPGGNSISACELTCILIGSLARPVVPAGQSMKEGRWDRKLYAGTELYGKTLAVLGLGRIGREVAIRMKTWGMRIIGYDPITTEAEAKAAGIEKMTLEEIWPLADYITVHTPLIPATRNLISAETLAKCKQGVKVVNVARGGIIDEQAVLDGLESGKVAGAAFDVYPEEPPKSAV----------TKALISHPKVVATPHLGASTSEAQVRVAVEVAEQFIALN-GTSPKYTSYAGVINKEALAHYQ--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P40054-1", "uniprot_id": "SERA_YEAST", "id": "P40054-1", "name": "D-3-phosphoglycerate dehydrogenase 1", "aln": "MTSIDINNLQNTFQQAMNMSGSPGAVCTSPTQSFMNTVPQRLNAVKHPKILKPFSTGDMKILLLENVNQTAITIFEEQGYQVEFYKSSLPEEELIEKIKDVHAIGIRSKTRLTSNVLQHAK-NLVCIGCFCIGTNQVDLDYATSRGIAVFNSPFSNSRSVAELVIAEIISLARQLGDRSIELHTGTWNKVAARCWEVRGKTLGIIGYGHIGSQLSVLAEAMGLHVLYYDIVTIMALGTAR--QVSTLDELLNKSDFVTLHVPATPETEKMLSAPQFAAMKDGAYVINASRGTVVDIPSLIQAVKANKIAGAALDVYPHEPAKNGEGSFNDELNSWTSELVSLPNIILTPHIGGSTEEAQSSIGIEVATALSKYINEGNSVGSVNFPEVALKSLSYDQ-----ENTVRVLYIHQNVPGVLKTVNDILSNHNIEKQFSDSNGEIAYLMADISSVDQSDIKDIYEQLNQTSAKISIRLLY------------------------------------------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P40510-1", "uniprot_id": "SER33_YEAST", "id": "P40510-1", "name": "D-3-phosphoglycerate dehydrogenase 2", "aln": "MSYSAADNLQDSFQRAMNFSGSPGAVSTSPTQSFMNTLPRRVSITKQPKALKPFSTGDMNILLLENVNATAIKIFKDQGYQVEFHKSSLPEDELIEKIKDVHAIGIRSKTRLTEKILQHAR-NLVCIGCFCIGTNQVDLKYAASKGIAVFNSPFSNSRSVAELVIGEIISLARQLGDRSIELHTGTWNKVAARCWEVRGKTLGIIGYGHIGSQLSVLAEAMGLHVLYYDIVTIMALGTAR--QVSTLDELLNKSDFVTLHVPATPETEKMLSAPQFAAMKDGAYVINASRGTVVDIPSLIQAVKANKIAGAALDVYPHEPAKNGEGSFNDELNSWTSELVSLPNIILTPHIGGSTEEAQSSIGIEVATALSKYINEGNSVGSVNFPEVSLKSLDYDQ-----ENTVRVLYIHRNVPGVLKTVNDILSDHNIEKQFSDSHGEIAYLMADISSVNQSEIKDIYEKLNQTSAKVSIRLLY------------------------------------------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . .:*: : :: . :::: * :* * .:. :** :::: .. :** *::* .:: . .* :* *.:::*: *: :.: *:*:* .*: *..**. : .*:* : .:: * *:: *: **.*.::* *:** ::: :: *:: : ** : . : : .*::: .*::*:*.* . * ::. :* *.*. *:* :** ::* ::: .:::.: .**.:**: .**.: *:. ::: **:*.**.*** . ::* : : : ", "identical_positions": 67, "similar_positions": 125, "identity": "11.11%" }, { "cls_id": "homologset.agr.MGI:1355331", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "G3V612-1", "uniprot_id": "G3V612_RAT", "id": "G3V612-1", "name": "", "aln": "MDSDASLVSSRPSSPEPDDLFLPARSKGGSSSGFTGGTVSSSTPSDCPPELSSELRGAMGTAGAHPGDKLGGGGFKSSSSSTSSSTSSAATSSTKKDKKQMTEPELQQLRLKINSRERKRMHDLNIAMDGLREVMPYAHGPSVRKLSKIATLLLARNYILMLTNSLEEMKRLVSEIYGGHHAGFHPSACGGLAHSTPLPTATAHPAAAAHAAHHPAVHHPILPPAAAAAAAAAAAAAVSSASLPGSGLSSVGSIRPPHGLLKSPSAAAAAPLGGGGGGSGGSGGFQHWGGMPCPCSMCQVPPPHHHVSAMGAGTLPRLTSDAK", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9EQW6-1", "uniprot_id": "OLIG2_MOUSE", "id": "Q9EQW6-1", "name": "Oligodendrocyte transcription factor 2", "aln": "MDSDASLVSSRPSSPEPDDLFLPARSKGGSSSGFTGGTVSSSTPSDCPPELSSELRGAMGASGAHPGDKLGGGGFKSSSSSTSSSTSSAATSSTKKDKKQMTEPELQQLRLKINSRERKRMHDLNIAMDGLREVMPYAHGPSVRKLSKIATLLLARNYILMLTNSLEEMKRLVSEIYGGHHAGFHPSACGGLAHSAPLPTATAHPAAAAHAAHHPAVHHPILPPAAAAAAAAAAAAAVSSASLPGSGLSSVGSIRPPHGLLKSPSAAAAAPLGGGGGGSGGSGGFQHWGGMPCPCSMCQVPPPHHHVSAMGAGTLPRLTSDAK", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q13516-1", "uniprot_id": "OLIG2_HUMAN", "id": "Q13516-1", "name": "Oligodendrocyte transcription factor 2", "aln": "MDSDASLVSSRPSSPEPDDLFLPARSKGSSGSAFTGGTVSSSTPSDCPPELSAELRGAMGSAGAHPGDKLGGSGFKSSSSSTSSSTSSAAASSTKKDKKQMTEPELQQLRLKINSRERKRMHDLNIAMDGLREVMPYAHGPSVRKLSKIATLLLARNYILMLTNSLEEMKRLVSEIYGGHHAGFHPSACGGLAHSAPLPAATAHPAAAAHAAHHPAVHHPILPPAAAAAAAAAAAAAVSSASLPGSGLPSVGSIRPPHGLLKSPSAAAAAPLGGGGGGSGASGGFQHWGGMPCPCSMCQVPPPHHHVSAMGAGSLPRLTSDAK", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "****************************.*.*.*******************:*******::**********.*****************:********************************************************************************************************:***:************************************************.*******************************.********************************:*********", "identical_positions": 310, "similar_positions": 13, "identity": "95.98%" }, { "cls_id": "homologset.agr.MGI:1355332", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O35682-1", "uniprot_id": "MYADM_MOUSE", "id": "O35682-1", "name": "Myeloid-associated differentiation marker", "aln": "MPVTVTRTTITTTTSSST------TVGSARALTQPLGLLRLLQLISTCVAFSLVASVGAWTGPMGNWAMFTWCFCFAVTLIILIVELGGLQAHFPLSWRNFPITFACYAALFCLSSSIIYPTTYVQ-FLAHGRTRDHAIAATTFSCVACLAYATEVAWTRARPGEITGYMATVPGLLKVFETFVACIIFAFISEPLLYNQKPALEWCVAVYAICFILAGVTILLNLGDCTNVLPIPFPTFLSGLALLSVLFYATAIVLWPLYQFDQRYQGQPRRSMDPSCTRSISYIQPNTVCFWDRRLAVSILTGINLLAYVSDLVYSTRLVFVKV", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6VBQ5-1", "uniprot_id": "MYADM_RAT", "id": "Q6VBQ5-1", "name": "Myeloid-associated differentiation marker", "aln": "MPVTVTRTTITTTSSSST------TVGSARALTQPLGLLRLLQLVSTCVAFSLVASVGAWTGPMGNWAMFTWCFCFAVTLIILIEELGGFQARFPLSWRNFPITFACYAALFCLSSSIIYPTTYVQ-FLPHGRSRDHAIAATTFSCVACLAYATEVAWTRARPGEITGYMATVPGLLKVFETFVACIIFAFISEPSLYQQRPALEWCVAVYAICFILAAVTVLLNLGDCTNMLPIPFPTFLSGLALLSVLLYATAIVLWPLYQFDQRYNSQPRRSMDPSCSR--SYVQPNEVCNWDRRLAVSILTGINLLAYVSDLVYSTRLVFVKV", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q96S97-1", "uniprot_id": "MYADM_HUMAN", "id": "Q96S97-1", "name": "Myeloid-associated differentiation marker", "aln": "MPVTVTRTTITTTTTSSSGLGSPMIVGSPRALTQPLGLLRLLQLVSTCVAFSLVASVGAWTGSMGNWSMFTWCFCFSVTLIILIVELCGLQARFPLSWRNFPITFACYAALFCLSASIIYPTTYVQ-FLSHGRSRDHAIAATFFSCIACVAYATEVAWTRARPGEITGYMATVPGLLKVLETFVACIIFAFISDPNLYQHQPALEWCVAVYAICFILAAIAILLNLGECTNVLPIPFPSFLSGLALLSVLLYATALVLWPLYQFDEKYGGQPRRSRDVSCSR----SHAYYVCAWDRRLAVAILTAINLLAYVADLVHSAHLVFVKV", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "X1WCE8-1", "uniprot_id": "X1WCE8_DANRE", "id": "X1WCE8-1", "name": "", "aln": "-MAVVLRS-------------------------SPLLWTRVAAMVFACVAFSVSMYGSRLTHGTGDWCVFCWSFSFVGTLLIILVEMFGLQTRAPVSWKNFPITFACYASLLCLSASIIFPLYFLKGFAGRTEMINCRIVSTVFSCLATIAYLSEVSLSKARPGEVSGYMATAPGLLKVCETFIACIIFVFISEPESYKQNAATQWCLAVYCICFILSAGIIVMCVGECTGCLPFSFARFLSTYALLAVSMYLSATIIWPIYKFDNKHGGQSHRP--NICGS------SIGLCPWDKLVAITVLSSLNFILYLADLIYSARLVFVNA", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "B0S636-1", "uniprot_id": "B0S636_DANRE", "id": "B0S636-1", "name": "", "aln": "MPVVVFRP-------------------------TQLMWARLAALVFTCVAFSVASHGGSLNGSIGDWSIFCWAFSFAGTLVVLLVELLGLQSRSPVSWNNFPITFACYAALLCLTASIIFPLYFLKGVTTYNEIRDHRIAASVFSCLATIAYFVEVSLARARPGEVAGYMATVPGLLKVCETFVASVIFVFISDPISYDSHSALKWCLAVYCICFVISAAIVVLCIGECTGCLPFPFARFLSAYALLAVLMYLTATIIWPVFKFDSRYNGQSNRP--YQCQS------RQGLCPWDKLVAVAVLTALNFLIYLADLAYSARLVFVTV", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ..* *. * *: :: :*****: . . *:*.:* *.*.* **:::: *: *:*:: *:**.**********:*:**::***:* ::: . . : *.:: ***:* :** **: ::*****::*****.****** ***:*.:**.***:* *. ..* :**:***.***:::. ::: :*:**. **:.*. *** ***:* :* :* ::**:::**.:: .*..*. * :* **: :*:::*:.:*:: *::** :*::****..", "identical_positions": 121, "similar_positions": 104, "identity": "37.0%" }, { "cls_id": "homologset.agr.MGI:1355333", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P55161-1", "uniprot_id": "NCKP1_RAT", "id": "P55161-1", "name": "Nck-associated protein 1", "aln": "MSRSVLQPSQQKLAEKLTILNDRGVGMLTRLYNIKKACGDPKAKPSYLIDKNLESAVKFIVRKFPAVETRNNNQQLAQLQKEKSEILKNLALYYFTFVDVMEFKDHVCDLLNTIDVCQVFFDITVNFDLTKNYLDLTVTYTTLMILLSRIEERKAIIGLYNYAHEMTHGASDREYPRLGQMIVDYEHPLKKMMEEFVPHSKSLSDALISLQMVYPRRNLSADQWRNAQLLSLISAPSTMLNPAQSDTMPCEYLSLDAMEKWIIFGFILCHGMLNTEATALNLWKLALQSSSCLSLFRDEVFHIHKAAEDLFVNIRGYNKRINDIRECKEAAVSHAGSMHRERRKFLRSALKELATVLSDQPGLLGPKALFVFMALSFARDEIIWLLRHADN--MPK---KSADDFIDKHIAELIFYMEELRAHVRKYGPVMQRYYVQYLSGFDAVVLNELVQNLSVCPEDESIIMSSFVNTMTSLSVKQVEDGEVFDFRGMRLDWFRLQAYTSVSKASLSLADHRELGKMMNTIIFHTKMVDSLVEMLVETSDLSIFCFYSRAFEKMFQQCLELPSQSRYSIAFPLLCTHFMSCTHELCPEERHHIGDRSLSLCNMFLDEMAKQARNLITDICTEQCTLSDQLLPKHCAKTISQAVNKKSKKQTGKKGEPEREKPGVESMRKNRLVVTNLDKLHTALSELCFSINYVPNMAVWEHTFTPREYLTSHLEIRFTKSIVGMTMYNQATQEIAKPSELLTSVREYMTVLQSIENYVQIDITRVFNNVLLQQTQHLDSHGEPTITSLYTNWYLETLLRQVSNGHIAYFPAMKAFVNLPTENELTFNAEEYSDISEMRSLSELLGPYGMKFLSESLMWHISSQVAELKKLVVENVDVLTQMRTSFDKPDQMAALFKRLSSVDSVLKRMTIIGVILSFRSLAQEALRDVLSYHIPFLVSSIEDFKDHIPRETDMKVAMNVYELSSAAGLPCEIDPALVVALSSQKSENISPEEEYKIACLLMVFVAVSLPTLASNVMSQYSPAIEGHCNNIHCLAKAINQIAAALFTIHKGS-IEDRLKEFLALASSSLLKIGQETDKTTTRNRESVYLLLDMIVQESPFLTMDLLESCFPYVLLRNAYHAVYKQSVTSSA--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P28660-1", "uniprot_id": "NCKP1_MOUSE", "id": "P28660-1", "name": "Nck-associated protein 1", "aln": "MSRSVLQPSQQKLAEKLTILNDRGVGMLTRLYNIKKACGDPKAKPSYLIDKNLESAVKFIVRKFPAVETRNNNQQLAQLQKEKSEILKNLALYYFTFVDVMEFKDHVCDLLNTIDVCQVFFDITVNFDLTKNYLDLTVTYTTLMILLSRIEERKAIIGLYNYAHEMTHGASDREYPRLGQMIVDYENPLKKMMEEFVPHSKSLSDALISLQMVYPRRNLSADQWRNAQLLSLISAPSTMLNPAQSDTMPCEYLSLDAMEKWIIFGFILCHGMLNTEATALNLWKLALQSSSCLSLFRDEVFHIHKAAEDLFVNIRGYNKRINDIRECKEAAVSHAGSMHRERRKFLRSALKELATVLSDQPGLLGPKALFVFMALSFARDEIIWLLRHADN--MPK---KSADDFIDKHIAELIFYMEELRAHVRKYGPVMQRYYVQYLSGFDAVVLNELVQNLSVCPEDESIIMSSFVNTMTSLSVKQVEDGEVFDFRGMRLDWFRLQAYTSVSKASLSLADHRELGKMMNTIIFHTKMVDSLVEMLVETSDLSIFCFYSRAFEKMFQQCLELPSQSRYSIAFPLLCTHFMSCTHELCPEERHHIGDRSLSLCNMFLDEMAKQARNLITDICTEQCTLSDQLLPKHCAKTISQAVNKKSKKQTGKKGEPEREKPGVESMRKNRLVVTNLDKLHTALSELCFSINYVPNMAVWEHTFTPREYLTSHLEIRFTKSIVGMTMYNQATQEIAKPSELLTSVRAYMTVLQSIENYVQIDITRVFNNVLLQQTQHLDSHGEPTITSLYTNWYLETLLRQVSNGHIAYFPAMKAFVNLPTENELTFNAEEYSDISEMRSLSELLGPYGMKFLSESLMWHISSQVAELKKLVVENVDVLTQMRTSFDKPDQMAALFKRLSSVDSVLKRMTIIGVILSFRSLAQEALRDVLSYHIPFLVSSIEDFKDHIPRETDMKVAMNVYELSSAAGLPCEIDPALVVALSSQKSENISPEEEYKIACLLMVFVAVSLPTLASNVMSQYSPAIEGHCNNIHCLAKAINQIAAALFTIHKGS-IEDRLKEFLALASSSLLKIGQETDKTTTRNRESVYLLLDMIVQESPFLTMDLLESCFPYVLLRNAYHAVYKQSVTSSA--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9Y2A7-1", "uniprot_id": "NCKP1_HUMAN", "id": "Q9Y2A7-1", "name": "Nck-associated protein 1", "aln": "MSRSVLQPSQQKLAEKLTILNDRGVGMLTRLYNIKKACGDPKAKPSYLIDKNLESAVKFIVRKFPAVETRNNNQQLAQLQKEKSEILKNLALYYFTFVDVMEFKDHVCELLNTIDVCQVFFDITVNFDLTKNYLDLIITYTTLMILLSRIEERKAIIGLYNYAHEMTHGASDREYPRLGQMIVDYENPLKKMMEEFVPHSKSLSDALISLQMVYPRRNLSADQWRNAQLLSLISAPSTMLNPAQSDTMPCEYLSLDAMEKWIIFGFILCHGILNTDATALNLWKLALQSSSCLSLFRDEVFHIHKAAEDLFVNIRGYNKRINDIRECKEAAVSHAGSMHRERRKFLRSALKELATVLSDQPGLLGPKALFVFMALSFARDEIIWLLRHADN--MPK---KSADDFIDKHIAELIFYMEELRAHVRKYGPVMQRYYVQYLSGFDAVVLNELVQNLSVCPEDESIIMSSFVNTMTSLSVKQVEDGEVFDFRGMRLDWFRLQAYTSVSKASLGLADHRELGKMMNTIIFHTKMVDSLVEMLVETSDLSIFCFYSRAFEKMFQQCLELPSQSRYSIAFPLLCTHFMSCTHELCPEERHHIGDRSLSLCNMFLDEMAKQARNLITDICTEQCTLSDQLLPKHCAKTISQAVNKKSKKQTGKKGEPEREKPGVESMRKNRLVVTNLDKLHTALSELCFSINYVPNMVVWEHTFTPREYLTSHLEIRFTKSIVGMTMYNQATQEIAKPSELLTSVRAYMTVLQSIENYVQIDITRVFNNVLLQQTQHLDSHGEPTITSLYTNWYLETLLRQVSNGHIAYFPAMKAFVNLPTENELTFNAEEYSDISEMRSLSELLGPYGMKFLSESLMWHISSQVAELKKLVVENVDVLTQMRTSFDKPDQMAALFKRLSSVDSVLKRMTIIGVILSFRSLAQEALRDVLSYHIPFLVSSIEDFKDHIPRETDMKVAMNVYELSSAAGLPCEIDPALVVALSSQKSENISPEEEYKIACLLMVFVAVSLPTLASNVMSQYSPAIEGHCNNIHCLAKAINQIAAALFTIHKGS-IEDRLKEFLALASSSLLKIGQETDKTTTRNRESVYLLLDMIVQESPFLTMDLLESCFPYVLLRNAYHAVYKQSVTSSA--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "B0S6R1-1", "uniprot_id": "NCKP1_DANRE", "id": "B0S6R1-1", "name": "Nck-associated protein 1", "aln": "MSRGAMQPSQQKLAEKLTILNDRGIGMLTRIYNIKKACGDPKAKPSYLIDKNLESAVKFIVRKFPAVETRNNNQQLAQLQKEKSEILKNLALYYFTFVDVMEFKDHVCELLNTIDACQVFFDITVNFDLTKNYLDLVVTYTTLMLLLSRIEERKAIIGLYNYAHEMTHGSSDREYPRLGQMIVDYENPLKKMMEEFVPHGKSLSDALVSLQMVYPRRNLSADQWRNAQLLSLISAPSTMLNPAQSDTMPCEYLSLDTMEKWIVFGFILCHAALNSDPAALSLWKLALQSSTCLCLFRDEVFHIHKAAEDLFVNIRGYNKRVNDIRECKESALSHAGSMHRERRKFLRSALKELATVLADQPGLLGPKALFVFMALSFARDEIIWLLRHADN--IQK---KSTDDFIDKHIAELIFYMEELRAHVRKYGPVMQRYYVQYLSGFDAVVLNELVQNLSVCPEDESIIMSSFVNTMTSLSVKQVEDGEVFDFRGMRLDWFRLQAYTSVSKASLGLADHRELGKMMNTIIFHTKMVDSLVEMLVETSDLSIFCFYSRAFEKMFQQCLELPSQSRYSISFPLLCTHFMSCTHELCPEERHHIGDRSLSLCNMFLDEMAKQARNLITDICTEQCTLSDQLLPKHCAKTISQAVNKKSKKQTGKKGEPEREKPGVESMRKNRLLVTNLDKLHTALSELCFSINYVPNMMVWEHTFTPREYLTSHLEIRFTKSIVGMTMYNQTTQEIAKPSELLTSVRAYMTVLQSIENYVQIDITRVFNNVLLQQTQHLDSHGEPTITSLYTNWYLETLLRQVSNGHIAYFPAMKAFVNLPTENELTFNAEEYSDISEMRSLSELLGPYGMKFLSESLMWHISSQVAELKKLVVDNVEVLTQMRTSFDKPDHMAALFKRLTSVDSVLKRMTIIGVILSFRSLAQEALRDVLSCHIPFLVSSVEDFKDHIPRETDMKVAMNVYELSSAAGLPCEIDPALVVALSSQKSENISPEEEYKIACLLMVFVAVSMPTLASNVMSQYSPAIEGHCNNIHCLAKAINQIAAALFTIHKGS-IEDRLKEFLALASSSLLKIGQETDKTTTRNRESVYLLLDMIVQESPFLTMDLLESCFPYVLLRNAYHAVYKQSVSSSA--", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P55162-1", "uniprot_id": "HEM_DROME", "id": "P55162-1", "name": "Membrane-associated protein Hem", "aln": "MAR-PIFPNQQKIAEKLIILNDRGLGILTRIYNIKKACGDTKSKPGFLSEKSLESSIKFIVKRFPNIDVKG----LNAIVNIKAEIIKSLSLYYHTFVDLLDFKDNVCELLTTMDACQIHLDITLNFELTKYYLDLVVTYVSLMIVLSRVEDRKAVLGLYNAAYELQNNQADTGFPRLGQMILDYEVPLKKLAEEFIPHQRLLTSALRSLTSIYALRNLPADKWREMQKLSLVGNPAILLKAVRTDTMSCEYISLEAMDRWIIFGLLLNHQMLGQYPEVNKIWLSALESSWVVALFRDEVLQIHQYIQATFDGIKGYSKRIGEVKEAYNTAVQKAALMHRERRKFLRTALKELALIMTDQPGLLGPKAIFIFIGLCLARDEILWLLRHNDNPPLLKNKGKSNEDLVDRQLPELLFHMEELRALVRKYSQVMQRYYVQYLSGFDATDLNIRMQSLQMCPEDESIIFSSLYNTAAALTVKQVEDNELFYFRPFRLDWFRLQTYMSVGKAALRIAEHAELARLLDSMVFHTRVVDNLDEILVETSDLSIFCFYNKMFDDQFHMCLEFPAQNRYIIAFPLICSHFQNCTHEMCPEERHHIRERSLSVVNIFLEEMAKEAKNIITTICDEQCTMADALLPKHCAKILSVQSARKKKDKSKSKHFDDIRKPGDESYRKTREDLTTMDKLHMALTELCFAINYCPTVNVWEFAFAPREYLCQNLEHRFSRDLVGMVMFNQETMEIAKPSELLASVRAYMNVLQTVENYVHIDITRVFNNCLLQQTQALDSHGEKTIAALYNTWYSEVLLRRVSAGNIVFSINQKAFVPISPEGWVPFNPQEFSDLNELRALAELVGPYGIKTLNETLMWHIANQVQELKSLVSTNKEVLITLRTSFDKPEVMKEQFKRLQDVDRVLQRMTIIGVIICFRNLVHEALVDVLDKRIPFLLSSVKDFQEHLPGGDQIRVAS---EMASAAGLLCKVDPTLATTLKSKKPE--FDEGEHLTACLLMVFVAVSIPKLARNENSFYRATIDGHSNNTHCMAAAINNIFGALFTICGQSDMEDRMKEFLALASSSLLRLGQESDKEATRNRESIYLLLDEIVKQSPFLTMDLLESCFPYVLIRNAYHGVYKQEQILGLAL", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*:* : *.***:**** ******:*:***:*********.*:**.:* :*.***::****::** ::.:. * : : *:**:*.*:***.****:::***:**:**.*:*.**:.:***:**:*** **** :**.:**::***:*:***::**** *:*: :. :* :*******:*** ****: ***:** : *:.** ** :*. ***.**:**: * ***:. *: :*:..::***.***:**::*::**:**::* * *. . . .:* **:** :.******::**: : * .*:**.**:.:::*. ::*:.:*. **********:****** :::**********:*:*:.*.:*****:***** ** : * ** :*::*:::.**:*:****** ****. ***************. ** :*.*.:********:**: ** ::*:******.*:* ** :********:* **.**:* :*:* **.:::::::***::**.* *:*************.: *:. *: ***:*:*.** *:***:*:** .****:******** :****: *:**:****:*:*:** ** ****::* ******** :* :*.*.:: .* : .*** ** **.* :*.:**** **:****:*** *.: ***.:*:***** .:** **::.:***.*:** * *********:*** **.***::****:********* ****** ****** **::**..** *.***:** *:*.: **** :..*. :.**.:*:**:.*:*:*:**:****:* *.*:*****:.** ***.** * :** :*******: * **** .** **:********:.**.*.:*** ***. :****:**::**::*:* :::** *::***** *::**:*..:*.*:*.* * *: ***********:*.** * * * .:*:**.** **:* ***:* .***** * :***:************::***:** :******:***** **::*****************:*****.****. . ", "identical_positions": 665, "similar_positions": 305, "identity": "58.54%" }, { "cls_id": "homologset.agr.MGI:1355334", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9WUQ3-1", "uniprot_id": "OLIG1_RAT", "id": "Q9WUQ3-1", "name": "Oligodendrocyte transcription factor 1", "aln": "MYYAVSQARVNAAPATMLRPQRPGDVQLGASLYELVGYRQPPISSSSST-------SSSSTASLLPKPAREKPEAPLAEPRGPAPES-----GGARADAKEEQQQQQLRRKINSRERKRMQDLNLAMDALREVILPYSAAHC------------QGAP--GRKLSKIATLLLARNYILLLGSSLQELRRALGD-----GAGPAAPRLLLAGLPLLAAAPGSVLLAPGAVGPPETLRPTKYLSLALDEPPCGQFALPAGGAGSPGLCSCAVCKFPHLVPAGLGLAAVQAQFSK", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9JKN5-1", "uniprot_id": "OLIG1_MOUSE", "id": "Q9JKN5-1", "name": "Oligodendrocyte transcription factor 1", "aln": "MYYAISQARVNAAPATMLRPQRPGDVQLGASLYELVGYRQPPISSSSS--------SSSSTASLLPKPAREKAEAPLAEPRGPAPES-----GGARADAKEEQQQQQLRRKINSRERKRMQDLNLAMDALREVILPYSAAHC------------QGAP--GRKLSKIATLLLARNYILLLGSSLQELRRALGD-----GAGPAAPRLLLAGLPLLAAAPGSVLLAPGAVGPPETLRPTKYLSLALDEPPCGQFSLPAGGAGSPGLCSCAVCKFPHLVPAGLGLAAVQAQFSK", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8TAK6-1", "uniprot_id": "OLIG1_HUMAN", "id": "Q8TAK6-1", "name": "Oligodendrocyte transcription factor 1", "aln": "MYYAVSQARVNAVPGTMLRPQRPGDLQLGASLYELVGYRQPPSSSSSSTSSTSSTSSSSTTAPLLPKAAREKPEAP-AEPPGPGPGSGAHPGGSARPDAKEEQQQQ-LRRKINSRERKRMQDLNLAMDALREVILPYSAAHC------------QGAP--GRKLSKIATLLLARNYILLLGSSLQELRRALGE-----GAGPAAPRLLLAGLPLLAAAPGSVLLAPGAVGPPDALRPAKYLSLALDEPPCGQFALPGGGAGGPGLCTCAVCKFPHLVPASLGLAAVQAQFSK", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A8WIQ7-1", "uniprot_id": "A8WIQ7_DANRE", "id": "A8WIQ7-1", "name": "", "aln": "---------MQAVSGVRYREQ-------GESSLQQLMPRMVRVTGSGG---------PGSNVGSLQGPLRS------SKPP--------------RELSSEE--QQELRRKINSRERKRMQDLNVAMDALREVMVPYSSSPTGVGGALQHPYLPPGAPTTGRRLSKISTLVLARNYILLLGSSLQEMRRLLGEVSIGMGVSGTVPRLLLTGGWPFLTGPGQLLLSP----PEQQLGVAKCPLLPQGAQEE-PLAWGPGSMSESPVCQCGVCRTPRVVHVNP-----AMRFPK", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ::*.... * * * * : : * :.*.. ..:.. * . *. ::* * :.** ** *****************:********::***:: *** **:****:**:***************:** **: *.. :.*****:* : :.**.:**:* * : * :* *. . :: *. . . :* *.**: *::* .. :*.*", "identical_positions": 98, "similar_positions": 62, "identity": "33.56%" }, { "cls_id": "homologset.agr.MGI:1355335", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P70566-1", "uniprot_id": "TMOD2_RAT", "id": "P70566-1", "name": "Tropomodulin-2", "aln": "--------------------------------------------------------------------------------------MALPFQKGLEKYKNIDEDELLGKLSEEELKQLENVLDDLDPESATLPAGFRQKDQTQKAATGPFDREHLLMYLEKEALEQKDREDFVPFTG-EKKGRVFIP---KEKPVETRKEEKVTLDPELEEALASASDTELYDLAAVLGVHNLLNNPKFDEETTNGQGRKGPVRN-VVKGEKAKPVFEEPPNPTNVEASLQQMKANDPSLQEVNLNNIKNIPIPTLKEFAKALETNTHVRKFSLAATRSNDPVALAFAEMLKVNKTLKSLNVESNFITGAGILALVEALRENDTLTEIKIDNQR-QQLGTAVEMEIAQMLEENSRILKFGYQFTKQGPRTRVAAAITKNND--------------LVRKKRVEGDRR-----------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9JKK7-1", "uniprot_id": "TMOD2_MOUSE", "id": "Q9JKK7-1", "name": "Tropomodulin-2", "aln": "--------------------------------------------------------------------------------------MALPFQKGLEKYKNIDEDELLGKLSEEELKQLENVLDDLDPESATLPAGFRQKDQTQKAATGPFDREHLLMYLEKEALEQKDREDFVPFTG-EKKGRVFIP---KEKPVETRKEEKVTLDPELEEALASASDTELYDLAAVLGVHNLLNNPKFDEETTNGEGRKGPVRN-VVKGEKAKPVFEEPPNPTNVEASLQQMKANDPSLQEVNLNNIKNIPIPTLKEFAKSLETNTHVKKFSLAATRSNDPVALAFAEMLKVNKTLKSLNVESNFITGTGILALVEALRENDTLTEIKIDNQR-QQLGTAVEMEIAQMLEENSRILKFGYQFTKQGPRTRVAAAITKNND--------------LVRKKRVEGDRR-----------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9NZR1-1", "uniprot_id": "TMOD2_HUMAN", "id": "Q9NZR1-1", "name": "Tropomodulin-2", "aln": "--------------------------------------------------------------------------------------MALPFQKELEKYKNIDEDELLGKLSEEELKQLENVLDDLDPESAMLPAGFRQKDQTQKAATGPFDREHLLMYLEKEALEQKDREDFVPFTG-EKKGRVFIP---KEKPIETRKEEKVTLDPELEEALASASDTELYDLAAVLGVHNLLNNPKFDEETANNKGGKGPVRN-VVKGEKVKPVFEEPPNPTNVEISLQQMKANDPSLQEVNLNNIKNIPIPTLREFAKALETNTHVKKFSLAATRSNDPVAIAFADMLKVNKTLTSLNIESNFITGTGILALVEALKENDTLTEIKIDNQR-QQLGTAVEMEIAQMLEENSRILKFGYQFTKQGPRTRVAAAITKNND--------------LVRKKRVEADRR-----------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A0B4K6N4-1", "uniprot_id": "A0A0B4K6N4_DROME", "id": "A0A0B4K6N4-1", "name": "", "aln": "MSDIEDVFGGSAEETKPEPDAQSKTSVVTEHTEEVIPGETEKMVTETIDEDGDVVEETTEVTRKTVKRTMKITETSATTKTTTLTTPAKLYGKDLSEYDDVDVESLLAQLSPEEITILA---KEVDPDDNFLPPDQRNSYECTKEATGPLNRKQLIEHINKQAIETPDQPEFEPFVQGKVRGKKWVPPPRDARDIEAEEQIAIDMGEEYEHALNDATQEEIIDLAAILGFHSMMNQDQYHASLLNKGQPVGLGWDGITKSTQQKLFPMDPPNNTDVEESIKRVKDDDSKLIDLNLNNIKNISDEKLEQLFAALPQNEHLEVLSLTNVGLTDKTALLLAAAIEKSKTLRVLNVETNFISPPVIVKLVQALLKCHTIEEFRASNQRSAVLGNKIEMEITDLVEKNSSLLRLGLHLEFNDARHRVAAHLQRNIDRIFRVQKLKPNLPKLILPGNMEIERDLVAYNRSATPSPSPSPQPPVDYEVEEDPDNMVIRGGGDAFDPDVDPDNMVVPGSRSVTPNYDDEGVYQAHTWTSASHGPSDQELHRWRLAVGFIRLGLGSLHILHRKKSIAYQ", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * : * *.:*.::* :.**.:** **:. * .::**:. **.. *:. : * ****::*::*: :::*:*:* *: :* **. : :*: ::* . : :*:.:: : :. * *.** .*:: *: ****:**.*.::*: ::. . * * : :.*. : * . :*** *:** *::::* :*..* ::********. .*.:: :* * *:. :**: . .* .*: :* :: .*** **:*:***: . *: **:** : .*: *:: .*** **. :****::::*:** :*::* :: :..* **** : :* * *: .:* :* ", "identical_positions": 119, "similar_positions": 133, "identity": "20.88%" }, { "cls_id": "homologset.agr.MGI:1355553", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0ABK0LH80-1", "uniprot_id": "A0ABK0LH80_RAT", "id": "A0ABK0LH80-1", "name": "", "aln": "----------------------------MKSACKPHGPPAGARGAPPCAGAAERAVSCAGPGRLESAARRRLAANARERRRMQG-----LNTAFDR--------------------------------------------LRRVVPQWGQDKKLSKYETLQMALSYIVALTRILAEAER------DWVGLRCEQ-----------------------RGRNHPYLPFPGARLQVDPEPYGQKFFGFQPESFPMAS------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9Z2E5-1", "uniprot_id": "ATOH7_MOUSE", "id": "Q9Z2E5-1", "name": "Transcription factor Atoh7", "aln": "----------------------------MKSACKPHGPPAGARGAPPCAGAAERAVSCAGPGRLESAARRRLAANARERRRMQG-----LNTAFDR--------------------------------------------LRRVVPQWGQDKKLSKYETLQMALSYIIALTRILAEAER------DWVGLRCEQ-----------------------RGRDHPYLPFPGARLQVDPEPYGQRLFGFQPEPFPMAS------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8N100-1", "uniprot_id": "ATOH7_HUMAN", "id": "Q8N100-1", "name": "Transcription factor ATOH7", "aln": "----------------------------MKS-CKPSGPPAGARVAPPCAGGTECAGTCAGAGRLESAARRRLAANARERRRMQG-----LNTAFDR--------------------------------------------LRRVVPQWGQDKKLSKYETLQMALSYIMALTRILAEAERFGS-ERDWVGLHCEH-----------------------FGRDH-YLPFPGAKLPGESELYSQRLFGFQPEPFQMAT------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8AW52-1", "uniprot_id": "ATOH7_DANRE", "id": "Q8AW52-1", "name": "Transcription factor atoh7", "aln": "--------------------------------MKPR--------RPSCADSGSDSDSRD-PEKFESAMRRRMAANARERKRMQG-----LNTAFDR--------------------------------------------LRKVVPQWGQDKKLSKYETLQMALSYIMALNRILSDAGRHVDPQKDWLNLQFDG-----------------------LQTEGYFMHYDSP---VESD-CMLSSFSYHYESL----------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P48987-1", "uniprot_id": "ATO_DROME", "id": "P48987-1", "name": "Protein atonal", "aln": "MSSSEIYRYYYKTSEDLQGFKTAAAEPYFNPMAAYNPGVTHYQFNGNTLASSSNYLSANGFISFEQASSDGWISSSPASHRSESPEYVDLNTMYNGGCNNMAQNQQYGMIMEQSVVSTAPAIPVASPPAVEVMGSSNVGTCKTIPASAGPKPKRSYTKKNQPSTTATSTPTAAAESSASVNLYTEEFQNFDFDNSALFDDSVEDDEDLMLFSGGEDFDGNDGSFDLADGENQDAAAGGSGKKRRGKQITPVVKRKRRLAANARERRRMQNLNQAFDRLRQYLPCLGNDRQLSKHETLQMAQTYISALGDLLR---", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9Y0A7-1", "uniprot_id": "AMOS_DROME", "id": "Q9Y0A7-1", "name": "Basic helix-loop-helix transcription factor amos", "aln": "--------------------------------MLTNNELMEQFYFPDEAPAIPEFLSNDTFQQLEQLMYQQEFSTSDSQSDGAN--SCSLEMYYDT-------------------------------------------------PSVLELEHMLNAQEQQQHHLQANPLGKNQGRSPR------YWNK----------------------------QQRSKPYDKLSTSMSSSTSSASSSSSSSAGFGGEVLKKRRLAANARERRRMNSLNDAFDKLRDVVPSLGHDRRLSKYETLQMAQAYIGDLVTLLSRDY", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . : :*. :.: . *: :: .. : : * . : : . : . . ", "identical_positions": 3, "similar_positions": 22, "identity": "0.95%" }, { "cls_id": "homologset.agr.MGI:1855672", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9JHB5-1", "uniprot_id": "TSNAX_RAT", "id": "Q9JHB5-1", "name": "Translin-associated protein X", "aln": "MNGKEGPGGFRKRKHDNFPHNQRREGKDASSSSPVMLAFKSFQQELDTRHDKYERLVKLSRDITVESKRTIFLLHRITS-APDMEEILTESESKLDG-VRQKMLQVAQELSGEDMHQFHRAVTTGLQEYVEAVSFQHFIR---------TRSLISMEEINRQLTFTTDDSGKESKAPPAD-----GQDKQLVTWRLKITPVDYLLGVADLTGELMRMCINSVGNGDIDTPFEVSQFLRQVYDGFSFIGNTGPYEVSKKLYTLKQSLSKVENACYALKVRGSEIPKHMLADVFSVKTEMIDQEESIS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9QZE7-1", "uniprot_id": "TSNAX_MOUSE", "id": "Q9QZE7-1", "name": "Translin-associated protein X", "aln": "MNGKEGPGGFRKRKHDTFPHNQRREGKDASLSSPVMLAFKSFQQELDARHDKYERLVKLSRDITVESKRTIFLLHRITS-APDMEEILTESESKLDG-VRQKILQVAQELSGEDMHQFHRAVTTGLQEYVEAVSFQHFIK---------TRSLISMEEINKQLTFTAEDSGKESKTPPAE-----GQEKQLVTWRLKLTPVDYLLGVADLTGELMRMCINSVGNGDIDTPFEVSQFLRQVYDGFSFIGNTGPYEVSKKLYTLKQSLAKVENACYALKVRGSEIPKHMLADVFSVKTDMIDQEESIS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q99598-1", "uniprot_id": "TSNAX_HUMAN", "id": "Q99598-1", "name": "Translin-associated protein X", "aln": "MSNKEGSGGFRKRKHDNFPHNQRREGKDVNSSSPVMLAFKSFQQELDARHDKYERLVKLSRDITVESKRTIFLLHRITS-APDMEDILTESEIKLDG-VRQKIFQVAQELSGEDMHQFHRAITTGLQEYVEAVSFQHFIK---------TRSLISMDEINKQLIFTTEDNGKENKTPSSD-----AQDKQFGTWRLRVTPVDYLLGVADLTGELMRMCINSVGNGDIDTPFEVSQFLRQVYDGFSFIGNTGPYEVSKKLYTLKQSLAKVENACYALKVRGSEIPKHMLADVFSVKTEMIDQEEGIS", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VF77-1", "uniprot_id": "Q9VF77_DROME", "id": "Q9VF77-1", "name": "", "aln": "MPKNGGAG-----HRNTAPRKRQIPAAQLDEDSPIVQQFRIYSNELIMKHDRHERIVKLSRDITIESKRIIFLLHSIDSRKQNKEKVLEEARQRLNKLIAVNFRAVALELRDQDVYQFRSSYSPGLQEFIEAYTYMEYLCHEDAEGENETKSVSDWQAIQAVMQYVEESSQPKEEPTEGEDVQAIAQVESPKKFQFFVDPTEYILGLSDLTGELMRRCINSLGSGDTDTCLDTCKALQHFYSGYISLNCQRARELWRKITTMKQSVLKAENVCYNVKVRGGEAAKWG-ATFDQKPADEVDEGFY--", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* : *.* :::. *:::: . : . .**:: *: :.:** :**::**:********:**** ***** * * : *.:* *:. :*: : :: ** ** .:*::**: : :.****::** :: .:: *:*: . : *: : :. :.. :.:.. .: .* :. .::: : *.:*:**::******** ****:*.** ** ::..: *::.*.*: :. . *: :*: *:***: *.**.** :****.* .* * . . :: :*: ", "identical_positions": 96, "similar_positions": 112, "identity": "31.37%" }, { "cls_id": "homologset.agr.MGI:1855688", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P58200-1", "uniprot_id": "VTI1B_RAT", "id": "P58200-1", "name": "Vesicle transport through interaction with t-SNAREs homolog 1B", "aln": "MATSAASSEHFEKLHEIFRGLLEDLQGVPERLLGTAGTEEKKKLVRDFDEKQQEANETLAEMEEELRYAP--LTFRNSMMSKLRNYRKDLAKLHREVRSTPLTATPGGRGDLKFGTYTLENEHLNRLQSQRALLLQGTESLNRATQSIERSHRIAAETDQIGSEIIEELGEQRDQLERTKSRLVNTNENLSKSRKILRSMSRKVITNKLLLSVIIVLELAILVGLVYYKFFRHH", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O88384-1", "uniprot_id": "VTI1B_MOUSE", "id": "O88384-1", "name": "Vesicle transport through interaction with t-SNAREs homolog 1B", "aln": "MAASAASSEHFEKLHEIFRGLLEDLQGVPERLLGTAGTEEKKKLVRDFDENQQEANETLAEMEEELRYAP--LTFRNPMMSKLRNYRKDLAKLHREVRSTPLTAAPGGRGDLKYGTYTLENEHLNRLQSQRALLLQGTESLNRATQSIERSHRIATETDQIGTEIIEELGEQRDQLERTKSRLVNTNENLSKSRKILRSMSRKVITNKLLLSVIILLELAILVGLVYYKFFRHH", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9UEU0-1", "uniprot_id": "VTI1B_HUMAN", "id": "Q9UEU0-1", "name": "Vesicle transport through interaction with t-SNAREs homolog 1B", "aln": "MASSAASSEHFEKLHEIFRGLHEDLQGVPERLLGTAGTEEKKKLIRDFDEKQQEANETLAEMEEELRYAP--LSFRNPMMSKLRNYRKDLAKLHREVRSTPLTATPGGRGDMKYGIYAVENEHMNRLQSQRAMLLQGTESLNRATQSIERSHRIATETDQIGSEIIEELGEQRDQLERTKSRLVNTSENLSKSRKILRSMSRKVTTNKLLLSIIILLELAILGGLVYYKFFRSH", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "B7Z0M0-1", "uniprot_id": "B7Z0M0_DROME", "id": "B7Z0M0-1", "name": "", "aln": "-----------------------------------------------------------------MSYA---------------GYSQLPSGSDQERRQAQLAAS----------TY---------------------DVLQRTTDSIQRSNQIAIETENMGAEVLGELGEQRESLLRTTRRLEDADQDLSKSRVIIRKLSREVLYNKIILILIIILEVGILVGLLVLKFAHL-", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q04338-1", "uniprot_id": "VTI1_YEAST", "id": "Q04338-1", "name": "t-SNARE VTI1", "aln": "--MSSLLISYESDFKTTLEQAKASLAEAPSQPLS-----QRNTTLKHVEQQQDELFDLLDQMDVEVNNSIGDASERATYKAKLREWKKTIQSDIKRPLQSLVDSGDRDRLFGDLNASNIDDD-------QRQQLLSNHAILQKSGDRLKDASRIANETEGIGSQIMMDLRSQRETLENARQTLFQADSYVDKSIKTLKTMTRRLVANKFISYAIIAVLILLILLVLFSKFK---", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : : : :. .: : : *::: : :: : :** **: :*:::: :* .**: * .: * ::.. :.** ::.::*.: **:: ** : : :: :: ** ", "identical_positions": 20, "similar_positions": 50, "identity": "8.55%" }, { "cls_id": "homologset.agr.MGI:1855689", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P62748-1", "uniprot_id": "HPCL1_MOUSE", "id": "P62748-1", "name": "Hippocalcin-like protein 1", "aln": "MGKQNSKLRPEVLQDLREHTEFTDHELQEWYKGFLKDCPTGHLTVDEFKKIYANFFPYGDASKFAEHVFRTFDTNSDGTIDFREFIIALSVTSRGKLEQKLKWAFSMYDLDGNGYISRSEMLEIVQAIYKMVSSVMKMPEDESTPEKRTDKIFRQMDTNNDGKLSLEEFIKGAKSDPSIVRLLQCDPSSASQF", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P62749-1", "uniprot_id": "HPCL1_RAT", "id": "P62749-1", "name": "Hippocalcin-like protein 1", "aln": "MGKQNSKLRPEVLQDLREHTEFTDHELQEWYKGFLKDCPTGHLTVDEFKKIYANFFPYGDASKFAEHVFRTFDTNSDGTIDFREFIIALSVTSRGKLEQKLKWAFSMYDLDGNGYISRSEMLEIVQAIYKMVSSVMKMPEDESTPEKRTDKIFRQMDTNNDGKLSLEEFIKGAKSDPSIVRLLQCDPSSASQF", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P37235-1", "uniprot_id": "HPCL1_HUMAN", "id": "P37235-1", "name": "Hippocalcin-like protein 1", "aln": "MGKQNSKLRPEVLQDLRENTEFTDHELQEWYKGFLKDCPTGHLTVDEFKKIYANFFPYGDASKFAEHVFRTFDTNGDGTIDFREFIIALSVTSRGKLEQKLKWAFSMYDLDGNGYISRSEMLEIVQAIYKMVSSVMKMPEDESTPEKRTDKIFRQMDTNNDGKLSLEEFIRGAKSDPSIVRLLQCDPSSASQF", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P42325-1", "uniprot_id": "NCAH_DROME", "id": "P42325-1", "name": "Neurocalcin homolog", "aln": "MGKQNSKLKPEVLEDLKQNTEFTDAEIQEWYKGFLKDCPSGHLSVEEFKKIYGNFFPYGDASKFAEHVFRTFDANGDGTIDFREFLCALSVTSRGKLEQKLKWAFSMYDLDGNGYISRQEMLEIVTAIYKMVGSVMKMPEDESTPEKRTDKIFRQMDRNKDGKLSLEEFIEGAKSDPSIVRLLQCDPQSH---", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q06389-1", "uniprot_id": "NCS1_YEAST", "id": "Q06389-1", "name": "Calcium-binding protein NCS-1", "aln": "MGAKTSKLSKDDLTCLKQSTYFDRREIQQWHKGFLRDCPSGQLAREDFVKIYKQFFPFGSPEDFANHLFTVFDKDNNGFIHFEEFITVLSTTSRGTLEEKLSWAFELYDLNHDGYITFDEMLTIVASVYKMMGSMVTLNEDEATPEMRVKKIFKLMDKNEDGYITLDEFREGSKVDPSIIGALNLYDGLI---", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "** :.*** : * *:: * * *:*:*:****:***:*:*: ::* *** :***:*....**:*:* .** :.:* *.*.**: .**.****.**:**.***.:***: :***: .*** ** ::***:.*::.: ***:*** *..***: ** *:** ::*:** .*:* ****: *: ", "identical_positions": 93, "similar_positions": 60, "identity": "48.19%" }, { "cls_id": "homologset.agr.MGI:1855690", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q5U214-1", "uniprot_id": "Q5U214_RAT", "id": "Q5U214-1", "name": "U1 small nuclear ribonucleoprotein A", "aln": "------------------MAVPETRPNHTIYINNLNEKIKKDELKKSLYAIFSQFGQILDILVSRSLKMRGQAFVIFKEVSSATNALRSMQGFPFYDKPMRIQYAKTDSDIIAKMKGTFVERDRKREKRKPKSQETPAAKKAVQGGAAAPVVGAVQ-PVPGMPPMTQAPRIMHHMPGQPPYMPPPGMIPPPGLAPGQIPPGAMPPQQLMPGQMPPAQPLSENPPNHILFLTNLPEETNELMLSMLFNQFPGFKEVRLVPGRHDIAFVEFDNEVQAGAARDALQGFKITQNNAMKISFAKK", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P09012-1", "uniprot_id": "SNRPA_HUMAN", "id": "P09012-1", "name": "U1 small nuclear ribonucleoprotein A", "aln": "------------------MAVPETRPNHTIYINNLNEKIKKDELKKSLYAIFSQFGQILDILVSRSLKMRGQAFVIFKEVSSATNALRSMQGFPFYDKPMRIQYAKTDSDIIAKMKGTFVERDRKREKRKPKSQETPATKKAVQGGGATPVVGAVQGPVPGMPPMTQAPRIMHHMPGQPPYMPPPGMIPPPGLAPGQIPPGAMPPQQLMPGQMPPAQPLSENPPNHILFLTNLPEETNELMLSMLFNQFPGFKEVRLVPGRHDIAFVEFDNEVQAGAARDALQGFKITQNNAMKISFAKK", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q62189-1", "uniprot_id": "SNRPA_MOUSE", "id": "Q62189-1", "name": "U1 small nuclear ribonucleoprotein A", "aln": "------------MATIATMPVPETRANHTIYINNLNEKIKKDELKKSLYAIFSQFGQILDILVSRIMKMRGQAFVIFKEVTSATNALRSMQGFPFYDKPMRIQYAKTDSDIIAKMKGTYVERDRKREKRKPKSQETPAAKKAVQGGAAAPVVGAVQ-PVPGMPPMPQAPRIMHHMPGQPPYMPPPGMIPPPGLAPGQIPPGAMPPQQLMPGQMPPAQPLSENPPNHILFLTNLPEETNELMLSMLFNQFPGFKEVRLVPGRHDIAFVEFDNEVQAGAARDALQGFKITQNNAMKISFAKK", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P43332-1", "uniprot_id": "SNRPA_DROME", "id": "P43332-1", "name": "U1 small nuclear ribonucleoprotein A", "aln": "---------------------MEMLPNQTIYINNLNEKIKKEELKKSLYAIFSQFGQILDIVALKTLKMRGQAFVIFKEIGSASNALRTMQGFPFYDKPMQIAYSKSDSDIVAKIKGTFKERPKK--VKPPK-------------------------PAPGTDEKKDKK---------------------------KKPSSAENSN-------PNAQ--TEQPPNQILFLTNLPEETNEMMLSMLFNQFPGFKEVRLVPNRHDIAFVEFTTELQSNAAKEALQGFKITPTHAMKITFAKK", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P40567-1", "uniprot_id": "MSL1_YEAST", "id": "P40567-1", "name": "U2 small nuclear ribonucleoprotein B''", "aln": "MVEPARKKQRIDRDTHHTVAEPVTEAKNTLYVSQLNEKINMQRLRVNLFLLFATFGEVLKVSMN-FKKQRGQAFITMRTIDQASLAQISLNGERFFGKPLKVEFSKSETKTL--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .::*:*:.:*****: :.*: .*: :*: **::*.: * *****: :: : .*: * :::* *:.**::: ::*:::. : ", "identical_positions": 26, "similar_positions": 40, "identity": "8.67%" }, { "cls_id": "homologset.agr.MGI:1855691", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZFL3-1", "uniprot_id": "D3ZFL3_RAT", "id": "D3ZFL3-1", "name": "mitogen-activated protein kinase kinase kinase", "aln": "MAGPCPGAGVLERAGSCWQDPLAEALSRGRSSPAVAGRGCARSRPLSVVYVLTREPGPGVEPGSGTEAEPLPLRCLREACAQLQSTRPPPQLRSLPFATLALGDTAALDSFYNADVVVLEVSNSLAQPSLFYHLGVRESFSMTNNVLLCSQAELPDLQALREDVFQKNSDCVGSYTLIPYVVTATGRVLCGDAGLLRGIADGLVQAGVGTEALLTPLVGRLVRLLEATPTDSCGYFRETIRQDIRKARERFS--GQQLRQELARLQRRLDSVELLSPDIIMNLLLSYRDVQDYSAIIELVETLQALP-TCDVAEQHNVCFHYTFALNRRNRPGDREKALAVLLPLVKHEGPVAPDLYCMCGRIYKDMFFSSSFQSTGHLEQAYHWYRKAFDVEPSLHSGINAAVLLIAAGKHFDDSEELQLIGMKLGCLLARKGCVEKMQYYWDVGFYLGAQILANDPIQVVLAAEQLYKLNAPIWYLVSVMETFLLYQHFRPTPEPSGGPVLRAHFWLHFLLQSCQPFKATPPQEDQCLVLVLEINKVLLPARLEIQGADPMSAVTLS----LLEPETQDDPSSWTFPVTSICGISASKLDQRCCFLYALPPAQDVQLCFPSVERCRWFCSQIQVLVMNPDSSAPTEEAEGTREVLEFDYEYSETGERLVLGKGTYGVVYAGRDRHTRVRIAIKEIPERDSRFSQPLHEEIALHKRLRHKNIVRYLGSASQGGYLKIFMEEVPGGSLSSLLRSVWGPLKDNESTISFYTRQILQGLSYLHENRIVHRDIKGDNVLINTFSGLLKISDFGTSKRLAGITPCTETFTGTLQYMAPEIIDQGPRGYGKAADIWSLGCTVIEMATGWPPFHELGSPQAAMFQVGMYKVHPPVPSSLSAEAQAFLLRTFEPDPRLRASAQELLGDPFLQPGKRSRSPGSPR-------------------HTPRPSGTPSSTSSPSADSATQSQTFPRPQAPSQHPPSPPKRCLSYGDTSQLRVPEESAAEEPASPEESSGLSLLHQESKRRAMLAAVLEQEVPILAENLLD---QEQDSRLS-RNHVELLLRCLGAQIHTPNRRQLAQELRALQAQLRAQSLSPALLKGPLFAFPDAVKQILRRRQIRPHWMFVLDSLLSRAVRAALAVLDAEA-----EKKAVSPKSEEWSQGESQQKPLESQPPLQSQLPPEQEPPSLMIQLGLLRAETDRLR------DILAEKERECQALVQQALHRVHAETRTYALASETPATLPK----------------------------------------------------DQKLVQWLQDLSVDPTTIQTLLSHSFTLQTLLTCATQDDLVYTRIRGGMVCRIWRAILAQRAGATSVTPGPRDAE-------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9WTR2-1", "uniprot_id": "M3K6_MOUSE", "id": "Q9WTR2-1", "name": "Mitogen-activated protein kinase kinase kinase 6", "aln": "MAGPCPRAGVLERAGSCWQDPLAEALSRGRSSPAVTGRGCARSRPLSVVYVLTREPGPGVEPGSGTEAEPLPLRCLREACAQLQGTRPPPQLRSLPFATLALGDTAALDSFYNADVVVLEVSSSLAQPSLFYHLGVRESFSMTNNVLLCSQAELPDLQALREDVFQKNSDCVGSYTLIPYVVTATGRVLCGDAGLLRGIADGLVQAGAGTEALLTPLVGRLVRLLEATPTDSCGYFRETIRQDIRQARERFS--GQQLRQELARLQRRLDSVELLSPDIVMNLLLSYRDVQDYSAIIELVETLQALP-TCDVAEQHNVCFHYTFALNRRNRPGDREKALAVLLPLVKYEGPVAPDLYCMCGRIYKDMFFTSGFQNAGHLEQAYHWYRKAFDVEPSLHSGINAAVLLIAAGQHFEDSEELRLIGMKLACLLARKGCVEKMQYYWDVGFYLGAQILANDPIQVVLAAEQLYKLNAPIWYLVSVMETFLLYQHFRPTPEPSGGPPLRAHFWLHFLLQSCQPFKMAPPQEDQCLVLVLEINKVLLPARLEIQGTDPMSAVTLS----LLEPETQEDPSSWTFPVTSICGISTSKLDQRCCFLYALPPAQDVQLCFPSVERCQRFCGLIQVLVMNPDSSAPTEEAEGAREVLEFDYEYSETGERLVLGRGTYGVVYAGRDRHTRVRIAIKEIPERDSRFSQPLHEEIALHKRLRHKNIVRYLGSASQGGYLKIFMEEVPGGSLSSLLRSVWGPLKDNESTISFYTRQILQGLSYLHENRIVHRDIKGDNVLINTFSGLLKISDFGTSKRLAGITPCTETFTGTLQYMAPEIIDQGPRGYGKAADIWSLGCTVIEMATGRPPFHELGSPQAAMFQVGMYKVHPPVPGSLSAEAQAFLLRTFEPDPRLRASAQELLGDPFLQPGKRSRSPGSPR-------------------HTPRPSGAPSGPSSPSADSATQSQTFPRPQAPSQHPPSPPKRCLSYGDTSQLRVPEEPAAEEPASPEESSGLSLLHQESKRRAMLAAVLEQEVPTLAENLLE---QEQDSRLS-KIHVELLLRCLGAQIHTPNRRQLAQELRTLQAQLRAQSLGPALLKGPLFAFPDAVKQILRRRQIRPHWMFVLDSLLSRAVRAALAVLDAES-----EKKAVLPRSEESSKEESQQKPQESQ-ALQSQLPPEQGPPSLMVELGLLRAETDRLR------DLLAEKERECQALVQQALHRVHAETRKYAPASETPATLPK----------------------------------------------------DQNLVRWLQELSVDPATIQTLLSHSFTLQTLLTCATQDDLVYTRIRGGMVCRIWRAILAQRAGATSVTPVPRDAE-------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O95382-1", "uniprot_id": "M3K6_HUMAN", "id": "O95382-1", "name": "Mitogen-activated protein kinase kinase kinase 6", "aln": "MAGPCPRSG-AERAGSCWQDPLAVALSRGRQLAAPPGRGCARSRPLSVVYVLTREPQPGLEPREGTEAEPLPLRCLREACAQVPRPRPPPQLRSLPFGTLELGDTAALDAFYNADVVVLEVSSSLVQPSLFYHLGVRESFSMTNNVLLCSQADLPDLQALREDVFQKNSDCVGSYTLIPYVVTATGRVLCGDAGLLRGLADGLVQAGVGTEALLTPLVGRLARLLEATPTDSCGYFRETIRRDIRQARERFS--GPQLRQELARLQRRLDSVELLSPDIIMNLLLSYRDVQDYSAIIELVETLQALP-TCDVAEQHNVCFHYTFALNRRNRPGDRAKALSVLLPLVQLEGSVAPDLYCMCGRIYKDMFFSSGFQDAGHREQAYHWYRKAFDVEPSLHSGINAAVLLIAAGQHFEDSKELRLIGMKLGCLLARKGCVEKMQYYWDVGFYLGAQILANDPTQVVLAAEQLYKLNAPIWYLVSVMETFLLYQHFRPTPEPPGGPPRRAHFWLHFLLQSCQPFKTACAQGDQCLVLVLEMNKVLLPAKLEVRGTDPVSTVTLS----LLEPETQDIPSSWTFPVASICGVSASKRDERCCFLYALPPAQDVQLCFPSVGHCQWFCGLIQAWVTNPDSTAPAEEAEGAGEMLEFDYEYTETGERLVLGKGTYGVVYAGRDRHTRVRIAIKEIPERDSRFSQPLHEEIALHRRLRHKNIVRYLGSASQGGYLKIFMEEVPGGSLSSLLRSVWGPLKDNESTISFYTRQILQGLGYLHDNHIVHRDIKGDNVLINTFSGLLKISDFGTSKRLAGITPCTETFTGTLQYMAPEIIDQGPRGYGKAADIWSLGCTVIEMATGRPPFHELGSPQAAMFQVGMYKVHPPMPSSLSAEAQAFLLRTFEPDPRLRASAQTLLGDPFLQPGKRSRSPSSPR-------------------HAPRPSDAPSASPTPSANSTTQSQTFPCPQAPSQHPPSPPKRCLSYGGTSQLRVPEEPAAEEPASPEESSGLSLLHQESKRRAMLAAVLEQELPALAENLHQEQKQEQGARLG-RNHVEELLRCLGAHIHTPNRRQLAQELRALQGRLRAQGLGPALLHRPLFAFPDAVKQILRKRQIRPHWMFVLDSLLSRAVRAALGVLGPEV-----EKEAVSPRSEELSNEGDSQQSPGQQSPLPVE--PEQGPAPLMVQLSLLRAETDRLR------EILAGKEREYQALVQRALQRLNEEARTYVLAPEPPTALST----------------------------------------------------DQGLVQWLQELNVDSGTIQMLLNHSFTLHTLLTYATRDDLIYTRIRGGMVCRIWRAILAQRAGSTPVTSGP-----------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VDS9-1", "uniprot_id": "Q9VDS9_DROME", "id": "Q9VDS9-1", "name": "", "aln": "---------------------------------------------MDVVCVMDTAVGDHLEDR----------QCALEEIKQAVQSAG-ANFQRVQFERLDFGETNVLETFYNADVAIIDLSILTQQRPLSYHYGVRESFGMKENILTYNDIDSKQTLSLKLSCAN--------YLFLSYKRNAET----NSCHLTSQPNSGNNSKEPNAEGRVPTLQWRLKRKLQDVEIQSKAHMREKFLSDMRTARDTYATNGAKLQSILHEMRKRLDDPHVLSGEVVHSFMCSLRDVQDYDAMVRLVNDLKNIPNTRKYVETGNMSFLYAFALNRRNRKGDREKALESSLKALEKKENHFPDMLCLCGRIYKDIFVESDYTDATSLAHAIKWYRQSFEVQPNEYAGINLATLLVIEGKEFTNTEELQHIGMTLNNLIGKKGSLSSLSEYWDVATFFEISVLANDYAKAIQAAECMFKLKPPNWYLKSTIGNISLIHRFRKKPEERQPPIEEQVFQFWMDFFLEATNTEEVKNSIRFPILILEPQKIYMPSYVTINMDADEKSIQIVNICLAHAKNACKKIHDFLFVASKIKSVSLYKRDDRCAYLYVHHNSDDFQIYFPSTERRQKFYDMILEMTADQVVFVNLSNDDAN---IEYEYDYDEQNRKMVLGKGTYGTVYAARDKQTQVRIAIKEVPEKNSQDVQPLHEEIKLHSQLRHRNIVRYLGSCSENGFFKIFMEQVPGGSLSDLLETKWGPLKDNESTMAFYSKQILEGLKYLHEQDIVHRDIKGDNVLVNTYSGVVKISDFGTSKRLARINPMTETFTGTLQYMAPEVIDQGVRGYGPAADIWSFGCTNVEMATGKPPFIELGSAHAAMFKVGFYKKHPNIPEELSANAKNFILRCFAISVMDRPSASQLLEDPFLQDKPRKVRPALPINTEFGRSISVPADRFVHKTTPPLSYNTTCNTPTTPELDITHSSSVDIDELPSNQFMLERRNSHGFLLSPEIEPSTPSLRTSISETSETDGFYRLKKDSQRRTTLSKVLALDESKICDIWLKKVDADQNSIAIRKSDLEVLIRGLRDYIMNENEKHLEATINELKQKLNNDAVALDHLHLALYSFQDAVVCVLRYHCIKPHWMFALDNLVKRAVQAAVTIFSPELGANLADKDLSGNDDESLRTSLMQKGSTESQEKQSLEKVLPTSNTREGVGLTPAESGGDALSSSMECARILRDIRDNQQKLQRQLLEQQRQSMRALHNISQELAHIYMGGRKRLRRTINGFNKKCHRMSTSVGGTSGVRPNIAGNPRRQLNKHHFGLHEVDEQLEQWLTQQEIDEFSKTLILNEGFTFDDFIYNMEKLDLMRLGLRVGIEVRLWKLIIQERVCTSSDCVDSPPSTYHKPIGGNSSFALIDNNNTLPSPTTTTPGTPGIKTKIKKSESEYDSCSE", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus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identical_positions": 435, "similar_positions": 395, "identity": "30.33%" }, { "cls_id": "homologset.agr.MGI:1855692", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q5FVM4-1", "uniprot_id": "NONO_RAT", "id": "Q5FVM4-1", "name": "Non-POU domain-containing octamer-binding protein", "aln": "-----------------------------------------------------------------------------------------MQSNKTFNLEKQNHTPRKHHQHHHQQHHQQQQQQQQQQQQQPPPPIPANGQQASSQNEG----------------------------------------------------------------------------------------------------------------------------------------LTIDLKNFRKPGEKTFTQRSRLFVGNLPPDITEEEMRKLFEKYGKAGEVFIHKDKGFGFIRLETRTLAEIAKVELDNMPLRGKQLRVRFACHSASLTVRNLPQYVSNELLEEAFSVFGQVERAVVIVDDRGRPSGKGIVEFSGKPAARKALDRCSEGSFLLTTFPRPVTVEPMDQLDDEEGLPEKLVIKN-QQFHKEREQPPRFAQPGSFEYEYAMRWKALIEMEKQQQDQVDRNIKEAREKLEMEMEAARHEHQVMLMRQDLMRRQEELRRMEELHNQEVQKRKQLELRQEEERRRREEEMR----RQQEEMMRRQQEGFKGTFPDAREQEIRMGQMAMGGAMGINNRGAMPPAPVPPGTPAPPGPAAMMPDGTLGLTPPTTERFGQAATMEGIGAIGGTPPAFNRPAPGAEFAPNKRRRY", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q99K48-1", "uniprot_id": "NONO_MOUSE", "id": "Q99K48-1", "name": "Non-POU domain-containing octamer-binding protein", "aln": "-----------------------------------------------------------------------------------------MQSNKAFNLEKQNHTPRKHHQHHHQQHHQQQQQQQQQQ---PPPPIPANGQQASSQNEG----------------------------------------------------------------------------------------------------------------------------------------LTIDLKNFRKPGEKTFTQRSRLFVGNLPPDITEEEMRKLFEKYGKAGEVFIHKDKGFGFIRLETRTLAEIAKVELDNMPLRGKQLRVRFACHSASLTVRNLPQYVSNELLEEAFSVFGQVERAVVIVDDRGRPSGKGIVEFSGKPAARKALDRCSEGSFLLTTFPRPVTVEPMDQLDDEEGLPEKLVIKN-QQFHKEREQPPRFAQPGSFEYEYAMRWKALIEMEKQQQDQVDRNIKEAREKLEMEMEAARHEHQVMLMRQDLMRRQEELRRMEELHNQEVQKRKQLELRQEEERRRREEEMR----RQQEEMMRRQQEGFKGTFPDAREQEIRMGQMAMGGAMGINNRGAMPPAPVPPGTPAPPGPATMMPDGTLGLTPPTTERFGQAATMEGIGAIGGTPPAFNRPAPGAEFAPNKRRRY", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q15233-1", "uniprot_id": "NONO_HUMAN", "id": "Q15233-1", "name": "Non-POU domain-containing octamer-binding protein", "aln": "-----------------------------------------------------------------------------------------MQSNKTFNLEKQNHTPRKHHQHHHQQQHHQQQQQQP-----PPPPIPANGQQASSQNEG----------------------------------------------------------------------------------------------------------------------------------------LTIDLKNFRKPGEKTFTQRSRLFVGNLPPDITEEEMRKLFEKYGKAGEVFIHKDKGFGFIRLETRTLAEIAKVELDNMPLRGKQLRVRFACHSASLTVRNLPQYVSNELLEEAFSVFGQVERAVVIVDDRGRPSGKGIVEFSGKPAARKALDRCSEGSFLLTTFPRPVTVEPMDQLDDEEGLPEKLVIKN-QQFHKEREQPPRFAQPGSFEYEYAMRWKALIEMEKQQQDQVDRNIKEAREKLEMEMEAARHEHQVMLMRQDLMRRQEELRRMEELHNQEVQKRKQLELRQEEERRRREEEMR----RQQEEMMRRQQEGFKGTFPDAREQEIRMGQMAMGGAMGINNRGAMPPAPVPAGTPAPPGPATMMPDGTLGLTPPTTERFGQAATMEGIGAIGGTPPAFNRAAPGAEFAPNKRRRY", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q04047-1", "uniprot_id": "NONA_DROME", "id": "Q04047-1", "name": "Protein no-on-transient A", "aln": "MESAGKQDNNATQQLPQRQQRGNQQANKNLGKHNAQKQNDSADGGPAEKKQRFGGPNAQNQNQNQNQNGGVTGGGGAVGGPNQNKNFGNNKGGFVGNRNRNNNRAGNQNR-TFPGNNNPNQKPNNETSKADGPNALAKNNEPATAAAGQNQANQNANKGQNQRQGQNQNQNQVHGQGNQGGPGNQGGAGNQGGQGNQGGAGNQGNGQ-GFRGRNAGNNQGGGFSGGPQNQQRDNRNRSGPRPGGGAGGAMNSTNMGGGGGGGGGGGPRGGEDFFITQRLRSISGPTFELEPVEVPTETKFSGRNRLYVGNLTNDITDDELREMFKPYGEISEIFSNLDKNFTFLKVDYHPNAEKAKRALDGSMRKGRQLRVRFAPNATILRVSNLTPFVSNELLYKSFEIFGPIERASITVDDRGKHMGEGIVEFAKKSSASACLRMCNEKCFFLTASLRPCLVDPMEVNDDTDGLPEKAFNKKMPDFNQERSIGPRFADPNSFEHEYGSRWKQLHNLFKTKQDALKRELKMEEDKLEAQMEYARYEQETELLRQELRKREVDNERKKLEWEMREKQAEEMRKREEETMRRHQTEMQSHMNRQEEDMLRRQQE---TLFMKAQQLNSLLDQQEGFGGGGGGNNSTFDNFAGNSNSPFEVFRGNNNNNSTMIGNNAAPNTQDSFAFEFGVNNMNQGGNQRGNNGGGNNVPWGRRRF-", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q24113-1", "uniprot_id": "Q24113_DROME", "id": "Q24113-1", "name": "Protein no-on-transient A", "aln": "MEGAVKKNSLNSSPLPQRQQRGNS-TNKNLGKPTPPKLNAASDGNPAEKKARLGG-NTQN-------GGGVAGGGGTGGGGGG----GGATGGVEFSRNRNRGGNQNENRQGFQVANNSHQKQINESPKPAAGNVPAKNNELSAGGGGQNQPNH-SNKGQGNQGDQGE-------QGNQGP--NFRGRGGGPNQPNQNANQEQSNGYPGNQGDNKGGQGQRGAGGG--KHQRGNRSR---RSGG--SGIMNSS-MGGGG--------QRGEDFFIAQRLLDISGPTHELPPIELPTDNKFVGRNRLYVGNLTSDTTDDDLREMFKPYGEIGDIFSNPEKNFTFLRLDYYQNAEKAKRALDGSLRKGRVLRVRFAPNA-IVRVTNLNQFVSNELLHQSFEIFGPIERAVICVDDRGKHTGEGIVEFAKKSSASACLRLCNEKCFFLTASLRPCLVEPMEVNNDNDGLPDKTLNKKSLEFRHERSVGPRFACLNSFEHEYGSRWKQLHDLFKSKQDSLKRELKMEEDKLEAQMEYARYEQETELLRQELKKRELDNERMKLEWEMREKQAEEIRKREEEYMHRYQNQLL----RHEEDMRARQQEN--DLLMQAKKLNMILDQQEGFGG----SNSGFEHFD----SPFEVF-GNNSNNSTMAG----PGGPD-----------NSDGNQHGHIDS-----WGHRRF-", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .. . :::. :.:: . :: :*: *:.:: :: * * :* .. * :..* *.**:****. * *::::*::*: **: .::* : :*.* *:::: ** ** **. :*: ****** :: : * ** :****** ::*.:** :*** : *****: *:*****: *.:* .* *.* .*:**: ** *:**: :* :***:* . *: :*.:**. **** .***:**. *** * :: * :** :.*::* .:*** :** **:*::. *:**:* :*: : .* : : . :: :::. *:** :* : :: *::*:* **** : .*:: : :.* *. ... : :* . :.*: . . . .. .:** ", "identical_positions": 135, "similar_positions": 147, "identity": "19.12%" }, { "cls_id": "homologset.agr.MGI:1855693", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P28656-1", "uniprot_id": "NP1L1_MOUSE", "id": "P28656-1", "name": "Nucleosome assembly protein 1-like 1", "aln": "-----------------MADIDNKEQSELD-QDLEDVEEVEEEETGEETKIKARQLTVQMMQNPQILAALQERLDGLVDTPTGYIESLPKVVKRRVNALKNLQVKCAQIEAKFYEEVHDLERKYAVLYQPLFDKRFEIINAIYEPTEEECEWKPDEEDEVSEELKEKAKIEDEKKDEEKEDPKGIPEFWLTVFKNVDLLSDMVQEHDEPILKHLKDIKVKFSDAGQP-MSFVLEFHFEPNDYFTNEVLTKTYRMRSEPDDSDPFSFDGPEIMGCTGCQIDWKK-GKNVTLKTIKKKQKHKGRGTVRTVTKTVSNDSFFNFFAPPEVP--ENGDLD-DDAEAILAADFEIGHFLRERIIPRSVLYFTGEAIEDDDDDYDEEGEEAD--EEGEEEGDEENDPDYDPKKDQNP------AECKQQ", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9Z2G8-1", "uniprot_id": "NP1L1_RAT", "id": "Q9Z2G8-1", "name": "Nucleosome assembly protein 1-like 1", "aln": "-----------------MADIDNKEQSELD-QDLEDVEEVEEEETGEETKIKARQLTVQMMQNPQILAALQERLDGLVDTPTGYIESLPKVVKRRVNALKNLQVKCAQIEAKFYEEVHDLERKYAVLYQPLFDKRFEIINAIYEPTEEECEWKPDEEDEVSEELKEKAKIEDEKKDEEKEDPKGIPEFWLTVFKN-DLLSDMVQEHDEPILKHLKDIKVKFSDAGQP-MSFILEFHFEPNEYFTNEVLTKTYRMRSEPDDSDPFSFDGPEIMGCTGCQIDWKK-GKNVTLKTIKKKQKHKGRGTVRTVTKTVSKTSFFNFFAPPEVP--ENGDLD-DDXEAILAADFEIGHFLRERIIPRSVLYFTGEAIEDDDDDYDEEGEEAD--EEGEEEGDEENDPDYDPKKDQNP------AECKQQ", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P55209-1", "uniprot_id": "NP1L1_HUMAN", "id": "P55209-1", "name": "Nucleosome assembly protein 1-like 1", "aln": "-----------------MADIDNKEQSELD-QDLDDVEEVEEEETGEETKLKARQLTVQMMQNPQILAALQERLDGLVETPTGYIESLPRVVKRRVNALKNLQVKCAQIEAKFYEEVHDLERKYAVLYQPLFDKRFEIINAIYEPTEEECEWKPDEEDEISEELKEKAKIEDEKKDEEKEDPKGIPEFWLTVFKNVDLLSDMVQEHDEPILKHLKDIKVKFSDAGQP-MSFVLEFHFEPNEYFTNEVLTKTYRMRSEPDDSDPFSFDGPEIMGCTGCQIDWKK-GKNVTLKTIKKKQKHKGRGTVRTVTKTVSNDSFFNFFAPPEVP--ESGDLD-DDAEAILAADFEIGHFLRERIIPRSVLYFTGEAIEDDDDDYDEEGEEAD--EEGEEEGDEENDPDYDPKKDQNP------AECKQQ", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M2BJ06-1", "uniprot_id": "A0A8M2BJ06_DANRE", "id": "A0A8M2BJ06-1", "name": "", "aln": "-----------------MADLDNKDQAEMDPADMEDVEE-EEEDAGED-NSKARQLTRQMMQNPQILAALQERLDGLVGSPSGYMESLPKVVKRRVNALKNLQVKCAHIEAKFYEEVHELERKYAALYQPLFDKRSEIVRAAYEPTDEECEWKQDEEEELTEEMKEKAKVEEEKKDEEKEDPKGIPEFWLTVFKNVDLLSEMLQEHDEPILKHLQDIKVKFSDAGQP-MSFTLEFHFEPNDFFTQTILTKTYKMRSEPDESDPFSFDGPEIMGCTGCTIDWTK-GKNVTLKTIKKKQKHKGRGTVRTVTKTVPNDSFFNFFSPPEVP--ESGELD-EDSEAVLAADFEIGHFIRERIVPRAVLYFTGEAIEDDDDDYDEEGEEADD-EEGEEEADEENDPDYEPKKDANPP-----EECKQQ", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9W1G7-1", "uniprot_id": "Q9W1G7_DROME", "id": "Q9W1G7-1", "name": "", "aln": "--------------------MDAPAEGHVD---PESCNEIEDEKSGSDCQSMPAYMNSVMRR---------QYLQQMVK-------MLPAPVQNRIVFLKNLQLQHLNIEAQFFEDVYKLEQKYQVQYQPLFDKRREIIEGKVDPAEEKPQWKEPESSTDNEADAEHFREALSSLKSIPKDAKGIPGFWLTVFRNTAIMSEMVQPHDEPAIRKLIDISIKYDNG----HSYTLEFHFDKNEYFSNSVLTKQYVLKSTVDPNDPFAFEGPEIYKCTGCTINWEK-KMNLTVKTIRKKQKHKERGAVRTIVKQVPTDSFFNFFSPPEVPS-DQEEVD-DDSQQILATDFEIGHFLRARIIPKAVLYYTGDIVDDEDDEDEEEYDENEEDEYDDDDAPPPKGPKSAGIKKQSP------NDCPNQ", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VAZ1-1", "uniprot_id": "Q9VAZ1_DROME", "id": "Q9VAZ1-1", "name": "", "aln": "------------------------------------METVRNRNPPRMKYTAPPKMESDLNFT--------------------------EKEKKTLTELKQLYLETINLDVALQRDIYNIEKKYEDKHNIIFDKRKKILDEFRKQNHGDVETN-----------------------------QSVPNFWLRVLKA--SYTEFISKRDEKILECLSDIRSRLYNEP-V-VKFDIEFHFDPNDYFTNTVLTKTYFLNCLPDPDDPLAYDGAEIYKCEGCVIDWKQ-TKDQTKTENQEP-------------------SFFEFFSPPLLPE-DTLDPNYCDVNAMLQNDFEVGFYLKERVIPKAVIFFTGEIADCQSSSGSETESEDTE---DESDAEEEDGVDK--------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P25293-1", "uniprot_id": "NAP1_YEAST", "id": "P25293-1", "name": "Nucleosome assembly protein", "aln": "MSDPIRTKPKSSMQIDNAPTPHNTPASVLNPSYLKNGNPVRAQAQEQDDKIGTINEEDILANQPLLLQSIQDRLGSLVGQDSGYVGGLPKNVKEKLLSLKTLQSELFEVEKEFQVEMFELENKFLQKYKPIWEQRSRIISGQEQPKPEQIAKGQEIVESLNETELLVDEEEKAQNDSEEEQVKGIPSFWLTALENLPIVCDTITDRDAEVLEYLQDIGLEYLTDGRPGFKLLFRFDSSANPFFTNDILCKTYFYQKELGYSGDFIYD-----HAEGCEISWKDNAHNVTVDLEMRKQRNKTTKQVRTIEKITPIESFFNFFDPPKIQNEDQDEELEEDLEERLALDYSIGEQLKDKLIPRAVDWFTGAALEFEFEEDEEEADEDEDEEEDDDHGLEDDDGESAEEQDDFAGRPEQAPECKQS", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . . . : :. : ** * : .:: : ::..:*.*: :: ::::* .*: . . :.:* *** .:. : : :* :. * ** . . :.*. . * :*:: :* * * . . .. : :: . ** *.* . : * . ***:** ** : : : * : * *:.:* :: :::*::* ::** : : .. .* .* .:... .. . ", "identical_positions": 43, "similar_positions": 94, "identity": "10.19%" }, { "cls_id": "homologset.agr.MGI:1855694", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q64339-1", "uniprot_id": "ISG15_MOUSE", "id": "Q64339-1", "name": "Ubiquitin-like protein ISG15", "aln": "MAWDLKVKMLGGNDFLVSVTNSMTVSELKKQIAQKIGVPAFQQRLA---HQT-AVLQDGLTLSSLGLGPSSTVMLVVQNCSEPLSILVRNERGHSNIYEVFLTQTVDTLKKKVSQREQVHEDQFWLSFEGRPMEDKELLGEYGLKPQCTVIKHLRLRGGGGDQCA--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D4A3X3-1", "uniprot_id": "D4A3X3_RAT", "id": "D4A3X3-1", "name": "Ubiquitin-like protein ISG15", "aln": "MTWNLKVKMLGGKEFLVSMTNSMMLSELKKQVAQKSGVPAFQQRLA---HQSGEMLQDGVALIRQGLSSGSTVMLMVENCSHPLSILVRNERGRSNVYEVQLTQTVEVLMRQVSQHEQVSQDQFWLSFNGRPMEDKEPLGEYGLTPHCTVIMNLRLRGGGDYYF---", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P05161-1", "uniprot_id": "ISG15_HUMAN", "id": "P05161-1", "name": "Ubiquitin-like protein ISG15", "aln": "MGWDLTVKMLAGNEFQVSLSSSMSVSELKAQITQKIGVHAFQQRLAV--HPSGVALQDRVPLASQGLGPGSTVLLVVDKCDEPLSILVRNNKGRSSTYEVRLTQTVAHLKQQVSGLEGVQDDLFWLTFEGKPLEDQLPLGEYGLKPLSTVFMNLRLRGGGTEPGGRS", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A2BHB8-1", "uniprot_id": "A2BHB8_DANRE", "id": "A2BHB8-1", "name": "", "aln": "--MQLTVKLLGGDVKRLEVSGDATVGILKQVISQYFNVPTFKQKLSAENGQRISLEDESRTLSSYGLNSDSVVMLLITTNPGTFQVFVKNEKGQVKTYDVDANETVDQLQTKIYQKERVPKDQQRLIFKGRQLESGMKLQDYDITSLSTIHMTLRLRGG--------", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :*.**:*.*. :.::.. :. ** ::* .* :*:*:*: :: .* **...*.*:*:: . .:.::*:*::*: . *:* .:** * :: * * .* * *:*: :*. * :*.:.. .*: ****** ", "identical_positions": 42, "similar_positions": 58, "identity": "25.15%" }, { "cls_id": "homologset.agr.MGI:1855695", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q5HZB6-1", "uniprot_id": "CLASR_RAT", "id": "Q5HZB6-1", "name": "CLK4-associating serine/arginine rich protein", "aln": "MWHEARKHERKLRGMMVDYKKRAERRREYYEKIKKDPAQFLQVHGRACKVHLDSAVALAAESPVNMMPWQGDTNNMIDRFDVRAHLDHIPDYTP--PLLTTISPEQESDERKCNYERYRGLVQNDFAGISEEQCLYQIYIDELYGG---LQRPSEDEKKKLAEKKASIGYTYEDS---------TVAEVEKVAEKPEEEESPAEEESNSDEDEVIPDIDVEVDVDELNQEQVADLNKQATTYGMADGDFVRMLRKDKEEAEAIKHAKALEEEKAMYSGRRSRRQRREFREKRLRGRKISPPSYARR-DSPTYDPYKRSPSESSSESRSRSRSPSPGREEKITFITSFGGSDEEA-------------------------AAAAAAAAASGAAPGKPPAPPQPGGPAPGRNASARRRSS-----SSS----ASRTSSSRSSSRSSSRSRRG--YYRSGRH-ARSRSRSWSRSRSRSRRYSRSRSRGRRHSDGGSRDG----------------HRYSRSPARRSGYAPRRRSRSRSRSGDRYKRGARGP-----------------RHHSSSHSRSSWSLSPSRSRSLTRSGSRSQSR-----------------------------------SRSRSQSHSQSQSHSPSPPREKLTRPAASPAVGEKLKKTE----PAAGKETGAAKPKLTP---------------------------------QERLKLRMQKALNRQFKADKKAAQEKMIQQEHERQEREDELRAMARKIRMKERE--------------------------------RREKEREEWER-------QYSRQS----------RSPSP---------------------RYSREYSSSRRRSRSRSRSPHYRH------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8CFC7-1", "uniprot_id": "CLASR_MOUSE", "id": "Q8CFC7-1", "name": "CLK4-associating serine/arginine rich protein", "aln": "MWHEARKHERKLRGMMVDYKKRAERRREYYEKIKKDPAQFLQVHGRACKVHLDSAVALAAESPVNMMPWQGDTNNMIDRFDVRAHLDHIPDYTP--PLLTTISPEQESDERKCNYERYRGLVQNDFAGISEEQCLYQIYIDELYGG---LQRPSEDEKKKLAEKKASIGYTYEDS---------TVAEVEKVAEKPEEEESPAEEESNSDEDEVIPDIDVEVDVDELNQEQVADLNKQATTYGMADGDFVRMLRKDKEEAEAIKHAKALEEEKAMYSGRRSRRQRREFREKRLRGRKISPPSYARR-DSPTYDPYKRSPSESSSESRSRSRSPSPGREEKITFITSFGGSDEEA-------------------------AAAAAAAAASGAAPGKPPAPPQTGGPAPGRNASTRRRSS-----SSS----ASRTSSSRSSSRSSSRSRRG--YYRSGRH-ARSRSRSWSRSRSRSRRYSRSRSRGRRHSDGGSRDG----------------HRYSRSPARRGGYVPRRRSRSRSRSGDRYKRGARGP-----------------RHHSSSHSRSSWSLSPSRSRSVTRSGSRSQSR-----------------------------------SRSRSQSHSQSQSHSPSPPREKLTRPAASPAVGEKLKKTE----PAAGKETGAAKPKLTP---------------------------------QERLKLRMQKALNRQFKADKKAAQEKMIQQEHERQEREDELRAMARKIRMKERE--------------------------------RREKEREEWER-------QYSRQS----------RSPSP---------------------RYSREYSSSRRRSRSRSRSPHYRH------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8N2M8-1", "uniprot_id": "CLASR_HUMAN", "id": "Q8N2M8-1", "name": "CLK4-associating serine/arginine rich protein", "aln": "MWHEARKHERKLRGMMVDYKKRAERRREYYEKIKKDPAQFLQVHGRACKVHLDSAVALAAESPVNMMPWQGDTNNMIDRFDVRAHLDHIPDYTP--PLLTTISPEQESDERKCNYERYRGLVQNDFAGISEEQCLYQIYIDELYGG---LQRPSEDEKKKLAEKKASIGYTYEDS---------TVAEVEKAAEKPEEEESAAEEESNSDEDEVIPDIDVEVDVDELNQEQVADLNKQATTYGMADGDFVRMLRKDKEEAEAIKHAKALEEEKAMYSGRRSRRQRREFREKRLRGRKISPPSYARR-DSPTYDPYKRSPSESSSESRSRSRSPTPGREEKITFITSFGGSDEEA-------------------------AAAAAAAAASGVTTGKPPAPPQPGGPAPGRNASARRRSS-----SSSSSSSASRTSSSRSSSRSSSRSRRGGGYYRSGRH-ARSRSRSWSRSRSRSRRYSRSRSRGRRHSGGGSRDG----------------HRYSRSPARRGGYGPRRRSRSRSHSGDRYRRGGRGL-----------------RHHSSSRSRSSWSLSPSRSRSLTRSRSHSPSP-----------------------------------SQSRSRSRSRSQSPSPSPAREKLTRPAASPAVGEKLKKTE----PAAGKETGAAKPKLTP---------------------------------QEKLKLRMQKALNRQFKADKKAAQEKMIQQEHERQEREDELRAMARKIRMKERE--------------------------------RREKEREEWER-------QYSRQS----------RSPSP---------------------RYSREYSSSRRRSRSRSRSPHYRH------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q1LUX7-1", "uniprot_id": "Q1LUX7_DANRE", "id": "Q1LUX7-1", "name": "", "aln": "MWQEARKHERKLRGMMVDYKRRGERRREYYEKIKKDPAQFLQVHGRAYKIHLDSAVALAAESPINMMPWQGDTNNMIDRFDVRAHLDYIPTYTPL-PILSTTTPEQESEERKCNYERYRGLVQNDFACISEEQCLYQIYVDELYGG---LQKPNEDEKKKLAEKKAQIGYTYEDS---------TVTEQDEQSKKGTEEDS---ENSESEEDEIIPDIDVEVDVDELSPEQVLEINKMATTYGMADGDFVWMLRKDKEEVEAIKHAKALEAEKAMYSGRRSRRQRREFREKYMKGRQISPPSYARR-DSPTYDPYKRPESDSSSESRSRSRTPG---NDKITFITSFGGSDEEG-------------------------ATATAAPPAAASS--------HSTSNSAGHSRGSRRRRS-----SSSPSSFSSRSSSHRSS-RSSSRSRRS----RRSRG-GRDRDSRYSRSRSRSRRRSDSRSRQR---SGGVSSR----------------RRYDRTRSRS---VDRGRDRNRDRDRGRRYTGRRRT-----------------RSRSRSRSVDRYRQR-SRSSAYRRGGSISQSP-----------------------------------SRSPAASRSSSPSSYSALP---------GSAAPDKLRKPE----TPGGKETGAAKPKMTP---------------------------------QEKLKLRMQKALNRQSKADKKAAQAKIQQQEHKRQEREGVLRAMARKIRMKERE--------------------------------RREKERDEWER-------QYGRQS----------HSPSPNA-------------------KYSRDYGSSRRRSRSRSRSPPYRY------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VC54-1", "uniprot_id": "Q9VC54_DROME", "id": "Q9VC54-1", "name": "Suppressor of white apricot N-terminal domain-containing protein", "aln": "MWHEARKQERKIRGLIVDYRKRAERRQYFYDKIQADPTQFLQLHGRRSKIYLDPAVAAAGDGAAIIVPWQGQQDNLIDRFDVRAHLDHIPPVNKTNAEGADGDSELTLEERQLNYERYRILAQNDFLNVSEDKFLHQLYLEEQFGANAQLEAERNLAKKKQKTGGATIGYSYEDTGDGATIGPQPFGAASSTVIGGAAAVAKGEKGDGSEESDSDIDMDVSIDIGKLDTSQAHELNACGRNYGMKSNDFFSHLTKDADEADALRIAREEEQEKMLLSGRKSRRERRAQKERRIANRPFSPPSYAAKEDKDKKGGGKGGEKEKEEDSESRSPSPAEAGPEKITYITSFGGEDEMQPHSKITISLTKPGLTLGESCINASSGAAIAAAAASSVSYAQKVKDNLDKLKVMNESSKRNRRRSRSHSRSRSRSATVSRSRSGSRRSGSRRRSRRSRSYHRRSRTRSRRRRRYYSRSRSRSRSRSRSLSRSRSRSRSRSRSGSWKRYKARSPSYKRSRKRYSYSSRSSSGSSYRRRSRSRSPSNRRSRVKKKTTPPPVATVGGYCLNTTTTTTTSTVTAVKMFQQQQQQPPAKATPPMISYPIPARMLNVNQALTATAPVAVQPQVVEPPPPPLKRYYGRKRGNDTSSSSSSGAENSEGSDNEEQQQPQLGKRAEDSDDMELDTASERSHALQPTMSSSSSTGNQTGKYSSATETKGSGHPSSGGGGRPNLRERLKRKMQNLLNRQYKADKRAEIEKTERERLQQQEREDEMRELALKLRRRRRELRHKYGTPSSGKLSDSDAESVASESQLAKSSTRRSRSRSESRRRSPPPETQHSRRSSSRTERRRRTRTPSPKYNRRQRSRSRSGSRVERKRRSHSRRRSGSRDRRRSRSRRSQSRRRRQRDRSIERNREREQYRQQHQQQNERLRGRDRDREADYGHGGSGSSNRGRVVISAPPKLKKLVDY", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "**:****:***:**::***::*.***: :*:**: **:****:*** *::**.*** *.:.. ::****: :*:***********:** . . : .* :**: ****** *.**** :**:: *:*:*::* :*. *: : *** * ***:***: .. .. : : . *:*.: *:**.:*:.:*. .*. ::* . .*** ..**. * ** :*.:*:: *: * ** : ***:***:** :*: : .* :****** : *. . . * .:...:*.*** :* :***:******.** .:* **..*:. : ... .** * * * **: * * ****. * .* .* * :******** * * ** * . . :**. : * *.*.*. . * : * : . : .:. : * . .:. . . * * * . . . .: ...: ...:.: * :*.::. :*:** :**: **** ****:* * ::. ::****. :* :* *:* :.** **.:.*.* .* *:.*:* ::*** :** ..** * ***** . * ", "identical_positions": 239, "similar_positions": 191, "identity": "24.87%" }, { "cls_id": "homologset.agr.MGI:1855696", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9JIE6-1", "uniprot_id": "TSLP_MOUSE", "id": "Q9JIE6-1", "name": "Thymic stromal lymphopoietin", "aln": "----------MVLLRSLFILQVLVRMGLTYNFSNCNFTSITKIYCNIIFHDLTGDLKGAK---FEQIEDCESKPACLLKIEYYTLNPIPGCPSLPDKTFARRTREALNDHCPGYPETERNDGTQEMAQEVQ-----NICLNQTSQILRLWYSFMQSPE---", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A0G2JUJ3-1", "uniprot_id": "A0A0G2JUJ3_RAT", "id": "A0A0G2JUJ3-1", "name": "", "aln": "----------MVLFRYLFILQV-VRLALTYNFSNCNFEMILRIYHATIFRDLLKDLNGIL---FDQIEDCDSRTACLLKIDHHTFNPVPGCPSLPEKAFALKTKAALINYCPGYSETERN-GTLEMTREIR-----NICLNQTSQILGLWLSCIQS-----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q969D9-1", "uniprot_id": "TSLP_HUMAN", "id": "Q969D9-1", "name": "Thymic stromal lymphopoietin", "aln": "MFPFALLYVLSVSFRKIFILQL-VGLVLTYDFTNCDFEKIKAAYLSTISKDLITYMSGTKSTEFNNTVSCSNRPHCLTEIQSLTFNPTAGCASLAKEMFAMKTKAALAIWCPGYSETQIN-ATQAMKKRRKRKVTTNKCLEQVSQLQGLWRRFNRPLLKQQ", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * :* :****: * : ***:*:**:* * * * :** :.* *:: .*..:. ** :*: *:** .**.**..: ** :*: ** ****.**: * .* * :. : * **:*.**: ** :. ", "identical_positions": 54, "similar_positions": 38, "identity": "33.54%" }, { "cls_id": "homologset.agr.MGI:1855697", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P29418-1", "uniprot_id": "ATP5E_RAT", "id": "P29418-1", "name": "ATP synthase F(1) complex subunit epsilon, mitochondrial", "aln": "MVAYWRQAGLSYIRFSQICAKAVRDALKTEFK-ANAEKTSGTSIKTVKIKKE--------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "M0R601-1", "uniprot_id": "M0R601_RAT", "id": "M0R601-1", "name": "ATP synthase F(1) complex subunit epsilon, mitochondrial", "aln": "MVAYWQQAGLSYIRFSQICAKAVRDALKTEFK-ANAEKTSGSSIKTVKVKKPD-------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P56382-1", "uniprot_id": "ATP5E_MOUSE", "id": "P56382-1", "name": "ATP synthase F(1) complex subunit epsilon, mitochondrial", "aln": "MVAYWRQAGLSYIRFSQICAKAVRDALKTEFK-ANAEKTSGSSIKIVKVSKKE-------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P56381-1", "uniprot_id": "ATP5E_HUMAN", "id": "P56381-1", "name": "ATP synthase F(1) complex subunit epsilon, mitochondrial", "aln": "MVAYWRQAGLSYIRYSQICAKAVRDALKTEFK-ANAEKTSGSNVKIVKVKKE--------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q5VTU8-1", "uniprot_id": "AT5EL_HUMAN", "id": "Q5VTU8-1", "name": "ATP synthase subunit epsilon-like protein, mitochondrial", "aln": "MVAYWRQAGLSYIRYSQICAKVVRDALKTEFK-ANAKKTSGNSVKIVKVKKE--------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F8W3H2-1", "uniprot_id": "F8W3H2_DANRE", "id": "F8W3H2-1", "name": "", "aln": "MVAYWRQAGLSYIRYSAICARVVRAALKPQIK-AEAIKNAESNVRVIKAKTT--------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VXN2-1", "uniprot_id": "SUN_DROME", "id": "Q9VXN2-1", "name": "Protein stunted", "aln": "MTA-WRAAGITYIQYSNIAARILRESLKTGLR-ADAAKRDASHVKFTPWANGKPAQR---QTQSES", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VH24-1", "uniprot_id": "Q9VH24_DROME", "id": "Q9VH24-1", "name": "", "aln": "MKA-WRDLGITYIQYSNIAARVVREALRIELR-ADAAKRNISHVKFTPWVNGKPVPRKKVERESES", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P21306-1", "uniprot_id": "ATP5E_YEAST", "id": "P21306-1", "name": "ATP synthase subunit epsilon, mitochondrial", "aln": "-MSAWRKAGISYAAYLNVAAQAIRSSLKTELQTASVLNRSQTDAFYTQYKNGTAASEPTPITK---", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : *: *::* : :.*: :* :*: :: *.. : . . ", "identical_positions": 7, "similar_positions": 18, "identity": "10.61%" }, { "cls_id": "homologset.agr.MGI:1855698", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I5ZRL0-1", "uniprot_id": "A0A8I5ZRL0_RAT", "id": "A0A8I5ZRL0-1", "name": "Reversion-inducing cysteine-rich protein with Kazal motifs", "aln": "---------------------------------------------------------------------------MASVRASARGALLLLLSAAGVAKVTGGLAPGSAGAVCCNHSKDNQMCRDVCEQIFSSKSES-RLKHLLQRAPDYCPETMVEIWSCMNSSLPDLRLSPCLLFCSCSDMQNSSCLSPHCTGVFKKSDGWVGLGCCELAIGLECRQACKQASSKNDISKVCRKEYENALFSCISRNEMGSVCCSYAGHHTNCREFCQAIFRTDSSPGPSQIKAVENYCASISPQLIHCVNNYTQSYPMRNPTDSLYCCDRAEEHACQSACRRILTSKKTEMEIVDGLIEGCKTQ----PLPQDPLWQCFLESSQSVHPGVTVHP-------------------PPSTGLDGAKLHCCSKANTSVCRELCTKLYSMSWGNTQSWQEFDRICEYNPGEVSMLACLADVREPCQLGCTNLTYCTNFNNRPTELFRSCTAQSDQGAMSDMRLWE-KGSIKMPFISIPVLDIRTCQPDLWKAVACSLQIKPCHRKSRGSIICKSDCVEILKKCGDQNKFPEAHTAESICEFLSPADDVEN---CIPLDTYLRPSALGN-IIEEVTHPCNPNPCPANELCEVNRKGCPSGDPCLPYSCVQGCKLGEASDFIVRQGALIQVP---------SSAGEVGCYKICSCGQSGLLENCMEMHCIDLQKSCIVGGKRKSHGTSFTIDCNVCSCFAGNLVCSTRLCLSEHSSDDDRRAFTGLPCNCADQFVPVCAQNGRTYPSACIARCVGLQDHQFEFGPCISKDPCN---PNLCPKSQRCVPKPQVCLTTFDKFGCSQYECVPRQLT-CDQ-ARDPVCDTDHVEHSNLCTLYQRGKS--LSYRGPCQP--FCRTTEPVCGHNGETYSSVCAAYSDRVAVDYYGRCQAVGVLSEHSAVTECAAVKCPSLSAIGCKPIIPPGACCPLCAG-MLRVLFDKEKLDTIAKVTNKKP---ITVLEILQKIRMHVSVPQCDVFGYLSIESEIVILIIPVD--HYPKALQIEACNKEAEKIESLINSDSPTLASHVPLSALIISQVQVSSSLPSSAVVGRLPPVHSLPLFLSLGLTVHLLQTCP", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9Z0J1-1", "uniprot_id": "RECK_MOUSE", "id": "Q9Z0J1-1", "name": "Reversion-inducing cysteine-rich protein with Kazal motifs", "aln": "---------------------------------------------------------------------------MASVRASPRSALLLLLAAAGVAEVTGGLAPGSAGAVCCNHSKDNQMCRDVCEQIFSSKSES-RLKHLLQRAPDYCPETMVEIWSCMNSSLP---------------------------GVFKKSDGWVGLGCCELAIGLECRQACKQASSKNDISKVCRKEYENALFSCISRNEMGSVCCSYAGHHTNCREFCQAIFRTDSSPGPSQIKAVENYCASISPQLIHCVNNYTQSYPMRNPTDSLYCCDRAEDHACQNACKRILMSKKTEMEIVDGLIEGCKTQ----PLPQDPLWQCFLESSQSVHPGVTVHP-------------------PPSTGLDGAKLHCCSKANTSTCRELCTKLYSMSWGNTQSWQEFDRICEYNPVEVSMLTCLADVREPCQLGCTNLTYCTNFNNRPTELFRSCTAQSDQGAMSDMKLWE-KGSIKMPFISIPVLDIKTCQPEMWKAVACSLQIKPCHSKSRGSIICKSDCVEILKKCGDQNKFPEEHTAESICEFLSPADDLES---CIPLDTYLRPSALGN-IIEEVTHPCNPNPCPANELCEVNRKGCPSADPCLPYSCVQGCKLGEASDFIVRQGTLIQVP---------SSAGEVGCYKICSCGQSGLLENCMEMHCIDLQKSCIVGGKRKSHGTSFTIDCNVCSCFAGNLVCSTRLCLSEHSSDDDRRTFTGLPCNCADQFVPVCAQNGRTYPSACIARCVGLQDHQFEFGPCISKNPCN---PNLCPKSQRCVPKPQVCLTTFDKFGCSQYECVPRQLT-CDQ-ARDPVCDTDHMEHSNLCTLYQRGKS--LSYRGPCQP--FCRAKEPVCGHNGETYSSVCAAYSDRVAVDYYGPCQAVGVLSEYSAVAECAAVKCPSLSAIGCKPIIPPGACCPLCAG-MLRVLFDKEKLDTIAKVTSKKP---ITVVEILQKVRMHVSVPQCDVFGYLSIESEIVILIIPVD--HYPKALQIEACNKEAEKIESLINSDSPTLASHVPLSALIISQVQVSSSLPSSAVVGR-PLFHSLLLLLSLGLTVHLLWTRP", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O95980-1", "uniprot_id": "RECK_HUMAN", "id": "O95980-1", "name": "Reversion-inducing cysteine-rich protein with Kazal motifs", "aln": "---------------------------------------------------------------------------MATVRASLRGALLLLLAVAGVAEVAGGLAPGSAGALCCNHSKDNQMCRDVCEQIFSSKSES-RLKHLLQRAPDYCPETMVEIWNCMNSSLP---------------------------GVFKKSDGWVGLGCCELAIALECRQACKQASSKNDISKVCRKEYENALFSCISRNEMGSVCCSYAGHHTNCREYCQAIFRTDSSPGPSQIKAVENYCASISPQLIHCVNNYTQSYPMRNPTDSLYCCDRAEDHACQNACKRILMSKKTEMEIVDGLIEGCKTQ----PLPQDPLWQCFLESSQSVHPGVTVHP-------------------PPSTGLDGAKLHCCSKANTSTCRELCTKLYSMSWGNTQSWQEFDRFCEYNPVEVSMLTCLADVREPCQLGCRNLTYCTNFNNRPTELFRSCNAQSDQGAMNDMKLWE-KGSIKMPFINIPVLDIKKCQPEMWKAIACSLQIKPCHSKSRGSIICKSDCVEILKKCGDQNKFPEDHTAESICELLSPTDDLKN---CIPLDTYLRPSTLGN-IVEEVTHPCNPNPCPANELCEVNRKGCPSGDPCLPYFCVQGCKLGEASDFIVRQGTLIQVP---------SSAGEVGCYKICSCGQSGLLENCMEMHCIDLQKSCIVGGKRKSHGTSFSIDCNVCSCFAGNLVCSTRLCLSEHSSEDDRRTFTGLPCNCADQFVPVCGQNGRTYPSACIARCVGLQDHQFEFGSCMSKDPCN---PNPCQKNQRCIPKPQVCLTTFDKFGCSQYECVPRQLA-CDQ-VQDPVCDTDHMEHNNLCTLYQRGKS--LSYKGPCQP--FCRATEPVCGHNGETYSSVCAAYSDRVAVDYYGDCQAVGVLSEHSSVAECASVKCPSLLAAGCKPIIPPGACCPLCAG-MLRVLFDKEKLDTIAKVTNKKP---ITVLEILQKIRMHVSVPQCDVFGYFSIESEIVILIIPVD--HYPKALQIEACNKEAEKIESLINSDSPTLASHVPLSALIISQVQVSSSVPSAGVRAR-PSCHSLLLPLSLGLALHLLWTYN", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A0R4IKU3-1", "uniprot_id": "RECK_DANRE", "id": "A0A0R4IKU3-1", "name": "Reversion-inducing cysteine-rich protein with Kazal motifs", "aln": "-------------------------------------------------------------------------------MSGCLQILTVLLCCRFWALVFS-----QDQSCCVHHAADIPRCRDACEQLASIRSES-RLRHLLHRLPSYCPETLSELWICINNSLP---------------------------GASRKSDGWVGLGCCELAISAECRRDCKQASSKNDISKVCKKDTENPLYSCITKNEMGSVCCSYAGRHTTCREYCQAIFRTDSSPTVSQISAVKEYCQSVSPPLILCVENYTRLHPTHRPIDSLHCCDRAEEAHCQLACKRILRTLSTEQEIMDGLISECGSQ----PLPQDPLWQCFLG---SAHPPANTDPES-----------------PPIAKMDSAKLHCCFKANTSICRNMCVEIS-TSWG-TQSWQEFDQHCEYNPVEMDLITCLADVREPCQLGCKELSYCTNFNNRPTELFRSCNVQSDQGALNDFKLWS-NGSIRMPLMNIPVLDIRRCRPEMWKTVACALQIKPCYSRSRGSVICRSDCVEILRQCGDRRRFAEAQTPERICDLLSPTDDPER---CIPLNRYLTASELES-SVEEVIHPCNPNPCPSSHLCHVNRKGCHVGHDCLPYYCVPGCKLGEASEFLVPADARLQVP---------VHSAQPGCYEVCVCGQSGRLENCAEMPCFDTSKSCQIAGQRRSHGSSFRVDCNPCSCFAGDAVCSSRQCVRSDSSEEDRRLFTGLPCGCADHFVPVCAGNGRTYPSACVARCVGFTDSQFVFGSCRSFDPCS---PNPCQRNQRCVPRRQVCLTDLSEFPCPQYECVSRPSS-CDQKLLDPVCDTDNMEHANLCVLNLRGKT--LAYSGHCQD--ACRRPREVCAHNGESYSTVCEAFSERVAVDYQGRCHAVGLESEFGSDSGCNAVPCPPLASDACQPVTPPGACCPVCAG-MLRILWNKAQMNIFAKLNRDQP---VSLHDILKILRLHVSVPQCDIFGYLSINSEIIILIAPVD--QQPTPLQIEACSKEAEKIDSLINSGSPTLVSHVPLSAFLSSELQLSSVRSSSCVSIS---VCVLLLLCSLILTLTSDL---", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VUJ2-1", "uniprot_id": "Q9VUJ2_DROME", "id": "Q9VUJ2-1", "name": "", "aln": "MRLSGWEILLFLLPFGVVSAVRQLEENQSIKNDHHHSVERQVRRRNNKSNASVDHHRHAPSSGSKKNSRSHSVSLDSDDYDWLDADTSEAIDSSEVTAVESIRSPGESYDIFTCCNQVFGSCRTACENLSLVEFATGTGGDNRDELHRYCQLHQVEFWTCVNQTFD----------------------------AITRGADWSGRRCCQFGVLPHCRNVCATSTRSP--VQNCRRSDEQTLYDCLERQEAADQCCGQA-RTSECLEACRAVFEPANDN--HDHVDINGACGDRNADVIQCVNNHTDMTPLANAEQYIPCCEYSSKEHCRHTCRNLLHQNATLMERSEVIFGRLEAAGCGSPLPQLPFWQCFLTVTGKLYVPGGSGRAGGSLAQGRISGQGGSLAEPNHLGMDAAKRQCCEQASSHKCRRLCNQIFTSNWWDARSS--FENECMDQPGERELRRCIESVDAPCELGCQGLSFCSNFNNRPTELFRSCTPEHDAAAREDWQLLQQRGTVRVLGQELFIKNTSRCAPDKWRALVCALQLKPCTRVGLFNGICSEDCHELLDECLDWT--LQHQRPKDICSRLKEKDDDDSPLPCISLESYLKPGDASPEEFQGITSPCAQKPCNGSEVCILQRGGNQG------YSCIPGCNLGQDSKLFVPFGSYVRLGKSNLHKKLEVGQFPLAEHIVCSCGLQGRLEQCQPLPSYMHAHCTLPGARSYRHGSSFYLECNLCSCFAGEITCTKQQCRLPGFVDSG---YTSLPCNCPAHYVPVCGSNGNTYPSACVAKCH-LPEGDYVYGACNARNACQAAPPNSCPSGTQCLDSRKVCLASMQRP-CLQYVCVNATASNCSTFHQGEVCDSQGRTYPNACALLKANPQGQVAYWSACQSSRFNTSPSPVCGINGVTYKSSYAARAEYVLVDYVGRCREVGLLVSDMG-RRCRTVKCPAPVSKHCRLIVPPGACCPLCAGGAFRIIYSRKQFDRAMYGLRAQSSTLLTLQGVLQQLDGLVQVSECQLTGFLTMEVGIFVAIVPSSSIKRPTHLQLEACAREAEKISSLINAQSPRITTNLALSCLTVSHLLEPTPNGATSYGPHAIWILPLLLLVSRVIIA-------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : * . . ** .**:: . : . .. ** *:* *:*.:: . :. .* * **::.: .**. * :: . : *::. *:.*:.*: ::* .. **. * : : * * *:*:*.. .. : :: * . .. :* **:*:* * .. : : **: :.. *: :*:.:* * * : :: : **** *:***** . : * :*.** :** :*.: **.:* :: .* ::* *:. * :* * .: *: .* **:*** *::*:*************. : * .* .* :* . .*:::: .: : : * *: *:::.*:**:*** . . ** .** *:* :* * : : .: **. *. ** . **.*: ** .. .: : ** :** ...:* ::* * * *: **:**: *.::* .: ::: . : :* ** .* **:* : . :. ..: **:** ::** ******: .*:.: * :.. :*.***.*. ::****. **.******:*:* : : :: :*.* : :.*. ** * . :*: :***: :.. * ** ** : *. . ***:: : * *.* . ::* . ** **. ** :*.: * :: * *** * *: **: . . * :* **. : *: : *******:*** :*:::.: ::: :. ::: :*: : *.*.:*:: *::::: *.: * * . : *. **:*** :*****.****: ** :.:::.**.: *.: .: :: * * * : ", "identical_positions": 266, "similar_positions": 293, "identity": "23.6%" }, { "cls_id": "homologset.agr.MGI:1855699", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q96AJ9-2", "uniprot_id": "VTI1A_HUMAN", "id": "Q96AJ9-2", "name": "Vesicle transport through interaction with t-SNAREs homolog 1A", "aln": "MSSDFEGYEQDFAVLTAEITSKIARVPRLPPD-EKKQMVANVEKQLEEAKELLEQMDLEVREIP--PQSRGMYSNRMRSYKQEMGKLETDFKRSRIAYSDEVRNELLGDDGNSSEN-------QRAHLLDNTERLERSSRRLEAGYQIAVETEQIGQEMLENLSHDREKIQRARERLRETDANLGKSSRILTGMLRRIIQNRILLVILGIIVVITILMAITFSVRRH-------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9JI51-1", "uniprot_id": "VTI1A_RAT", "id": "Q9JI51-1", "name": "Vesicle transport through interaction with t-SNAREs homolog 1A", "aln": "MSADFEGYEQDFAVLTAEITSKISRVPRLPPD-EKKQMVANVEKQLEEARELLEQMDLEVREIP--PQSRGMYSNRMRSYKQEMGKLETDFKRSRIAYSDEVRNELLGDAGNSSENQLIKLREERAHLLDNTERLERSSRRLEAGYQIAVETEQIGQEMLENLSHDRERIQRARERLRETDANLGKSSRILTGMLRRIIQNRILLVILGIIVVITILTAITFFVRGH-------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O89116-1", "uniprot_id": "VTI1A_MOUSE", "id": "O89116-1", "name": "Vesicle transport through interaction with t-SNAREs homolog 1A", "aln": "MSSDFEGYEQDFAVLTAEITSKIARVPRLPPD-EKKQMVANVEKQLEEARELLEQMDLEVREIP--PQSRGMYSNRMRSYKQEMGKLETDFKRSRIAYSDEVRNELLGDAGNSSEN-------QRAHLLDNTERLERSSRRLEAGYQIAVETEQIGQEMLENLSHDREKIQRARDRLRDADANLGKSSRILTGMLRRIIQNRILLVILGIIVVIAILTAIAFFVKGH-------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A2R8Q5I2-1", "uniprot_id": "A0A2R8Q5I2_DANRE", "id": "A0A2R8Q5I2-1", "name": "", "aln": "MSSDFEAYEQDFGTLTAEITNKIGRIPKLAGE-EKTQLVLNVDKQLEEVRELMEQMDLEVREIP--IQSRAMYNSRLKSYKQEMEKLEKDFKRSRIAYSDEVRNELLGDDGSSSETQLIKLREERAHLLDNTERLERSSRRLEAGYQIAVETEQVGQEILANLHSDREKIQRSRDRLRETDANLGKSSRILTGMLRRIIQNRILVFILGAIILLTIVLAIYFNLRGH-------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9W0N6-1", "uniprot_id": "Q9W0N6_DROME", "id": "Q9W0N6-1", "name": "", "aln": "-MSLLEQYEQQYATLIAEITAHIGRLQQQNNNSERHDLCSKIDSSLPEAQELLEQMGLEVRELN--PGLRSSFNGKLQVAQAELKRLQAEYRLTKDKQRSQANTFTTLDLGDSYEDVSIS-TDQRQRLLDNSERIERTGNRLTEGYRVALETEQLGAQVLNDLHHQRETLQGARARLRETNAELGRASRTLNTMMLRALREKVVLYGVGVCFVVAVGVSLYLTFAPSSSSTASS", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q04338-1", "uniprot_id": "VTI1_YEAST", "id": "Q04338-1", "name": "t-SNARE VTI1", "aln": "MSSLLISYESDFKTTLEQAKASLAEAPSQPLS-QRNTTLKHVEQQQDELFDLLDQMDVEVNNSIGDASERATYKAKLREWKKTIQSDIKRPLQSLVDSGDRDRLFGDLNASNIDDD-------QRQQLLSNHAILQKSGDRLKDASRIANETEGIGSQIMMDLRSQRETLENARQTLFQADSYVDKSIKTLKTMTRRLVANKFISYAIIAVLILLILLVLFSKFK---------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : **.:: . : . :.. . :: :::.. * :*::**.:**.: *. :. ::: : : : .. . : .. : :* :**.* ::::. ** . ::* *** :* ::: :* :** :: :* * :::: :.:: : *. * * : ::.: : .:: : : . ", "identical_positions": 28, "similar_positions": 84, "identity": "11.97%" }, { "cls_id": "homologset.agr.MGI:1855700", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "F1MA46-1", "uniprot_id": "F1MA46_RAT", "id": "F1MA46-1", "name": "Protocadherin-12", "aln": "TMLLLPFLLGLLGPGSYLFISGACQEVATVTVKFQVAEEVPSGTVIGKLSQEPGVEERRGKAGDAFQILQLPQALPIQMNSEDGLLNTSSRLDREKLCRQQDPCLVSFDVLAT--GASALIHVEIQVLDINDHQPQFPKDEQELEISESASLHTRIPLDRALDQDTGPNSLYSYSLSPSEHFALDVIVGPDETKHAELVVVKELDREVHSYFDLVLTAYDNGNPPKSGTSVVKVNVLDSNDNSPVFAESSLALEIPEDTAPGTLLINLTATDPDQGPNGEVEFFFGKHVSPEVMNTFGIDAKTGQIVLLQPLDYEKNPAYEVDVQARDLGPNSIPGHCKVLIKVLDVNDNAPSIHITWASQMS---LVSEDLPRDSFIALVSANDLDSGNNGLVNCWLNQELGHFRLKRTNGNTYMLLTSAMLDREQWPTYTLTVFAQDQGPQALSAEKELQIQVSDVNDNAPVFEKSRYEVSTWENNPPSLHLITLKAHDADLGSNGKVSYRIKDS----PVSHLVIIDSETGEVTAQRSLDYEEMAGFEFQVIAEDRGQPQLSSSISVWVSLLDANDNTPEVIQPALSEGKATLSVLVNASTGHLLLPIESPSGMDPAGTGPTPPKATHSPWSFLLVTIVARDADSGANGELLYSIQSGNDAHLFVLSPSLGQLFINVTNASSLIGSQWDLGIVVEDQGSPSLQTQVSLKVVFVTSMDHLRDSAHE-PGILSTPALAMICLAVLLAVFGLILALLVSICRIEKRDNRAYNCREAESMYRHQPKRPQKHIQKADIHLVPMLRAQEDEAEEVRPPHKDTSKETLMEAGWDSCLQAPFHLTPTLYRTLRNQGN---QGALAESQ-EVLQDTFNFLFN--HPRQRNASRENLNLPESPPTLRQPLLKPLKVPGSPIAR-VTGDQGSKEAPQSPPASSATLRRQRNLNGKVSPKGESSPHQILRSLVRLSVAAFAERNPVEELAGDSPPVQQISQLLSLLHQGQFQPKPNHRGNKYSAKPG-SSRATIPDTDGLG-IRPGGLSEPDLEEGPPSPEEDLSVKRLLEEELSSLLDPNTGLALDKLSPPDPAWMARLSLPLTTNYRDNLSSPDAAAS----------EEPRTFQTFGKTVGPGPELSATGTRLASTFVSEMSSLLEMLLEQN-TVPVEAASAALRRLS-VCGRTLSLDLATSGASGSEAQL--GRKKAAES----SLGCGRNL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O55134-1", "uniprot_id": "PCD12_MOUSE", "id": "O55134-1", "name": "Protocadherin-12", "aln": "MMLLLPFLLGLLGPGSYLFISGDCQEVATVMVKFQVTEEVPSGTVIGKLSQELRVEERRGKAGDAFQILQLPQALPVQMNSEDGLLSTSSRLDREKLCRQEDPCLVSFDVLAT--GASALIHVEIQVLDINDHQPQFPKDEQELEISESASLHTRIPLDRALDQDTGPNSLYSYSLSPSEHFALDVIVGPDETKHAELVVVKELDRELHSYFDLVLTAYDNGNPPKSGISVVKVNVLDSNDNSPVFAESSLALEIPEDTVPGTLLINLTATDPDQGPNGEVEFFFGKHVSPEVMNTFGIDAKTGQIILRQALDYEKNPAYEVDVQARDLGPNSIPGHCKVLIKVLDVNDNAPSILITWASQTS---LVSEDLPRDSFIALVSANDLDSGNNGLVHCWLNQELGHFRLKRTNGNTYMLLTNATLDREQWPIYTLTVFAQDQGPQPLSAEKELQIQVSDVNDNAPVFEKSRYEVSTWENNPPSLHLITLKAHDADLGSNGKVSYRIKDS----PVSHLVIIDFETGEVTAQRSLDYEQMAGFEFQVIAEDRGQPQLASSISVWVSLLDANDNAPEVIQPVLSEGKATLSVLVNASTGHLLLPIENPSGMDPAGTG-IPPKATHSPWSFLLLTIVARDADSGANGELFYSIQSGNDAHLFFLSPSLGQLFINVTNASSLIGSQWDLGIVVEDQGSPSLQTQVSLKVVFVTSVDHLRDSAHE-PGVLSTPALALICLAVLLAIFGLLLALFVSICRTERKDNRAYNCREAESSYRHQPKRPQKHIQKADIHLVPVLRAHENETDEVRPSHKDTSKETLMEAGWDSCLQAPFHLTPTLYRTLRNQGN---QGELAESQ-EVLQDTFNFLFN--HPRQRNASRENLNLPESPPAVRQPLLRPLKVPGSPIAR-ATGDQDKEEAPQSPPASSATLRRQRNFNGKVSPRGESGPHQILRSLVRLSVAAFAERNPVEEPAGDSPPVQQISQLLSLLHQGQFQPKPNHRGNKYLAKPGGSSRGTIPDTEGLVGLKPSGQAEPDLEEGPPSPEEDLSVKRLLEEELSSLLDPNTGLALDKLSPPDPAWMARLSLPLTTNYRDNLSSPDATTS----------EEPRTFQTFGKTVGPGPELSPTGTRLASTFVSEMSSLLEMLLGQH-TVPVEAASAALRRLS-VCGRTLSLDLATSGASASEAQ---GRKKAAES----RLGCGRNL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9NPG4-1", "uniprot_id": "PCD12_HUMAN", "id": "Q9NPG4-1", "name": "Protocadherin-12", "aln": "MMQLLQLLLGLLGPGGYLFLLGDCQEVTTLTVKYQVSEEVPSGTVIGKLSQELGREERRRQAGAAFQVLQLPQALPIQVDSEEGLLSTGRRLDREQLCRQWDPCLVSFDVLAT--GDLALIHVEIQVLDINDHQPRFPKGEQELEISESASLRTRIPLDRALDPDTGPNTLHTYTLSPSEHFALDVIVGPDETKHAELIVVKELDREIHSFFDLVLTAYDNGNPPKSGTSLVKVNVLDSNDNSPAFAESSLALEIQEDAAPGTLLIKLTATDPDQGPNGEVEFFLSKHMPPEVLDTFSIDAKTGQVILRRPLDYEKNPAYEVDVQARDLGPNPIPAHCKVLIKVLDVNDNIPSIHVTWASQPS---LVSEALPKDSFIALVMADDLDSGHNGLVHCWLSQELGHFRLKRTNGNTYMLLTNATLDREQWPKYTLTLLAQDQGLQPLSAKKQLSIQISDINDNAPVFEKSRYEVSTRENNLPSLHLITIKAHDADLGINGKVSYRIQDS----PVAHLVAIDSNTGEVTAQRSLNYEEMAGFEFQVIAEDSGQPMLASSVSVWVSLLDANDNAPEVVQPVLSDGKASLSVLVNASTGHLLVPIETPNGLGPAGTD-TPPLATHSSRPFLLTTIVARDADSGANGEPLYSIRSGNEAHLFILNPHTGQLFVNVTNASSLIGSEWELEIVVEDQGSPPLQTRALLRVMFVTSVDHLRDSARK-PGALSMSMLTVICLAVLLGIFGLILALFMSICRTEKKDNRAYNCREAESTYRQQPKRPQKHIQKADIHLVPVLRGQAGEPCEVGQSHKDVDKEAMMEAGWDPCLQAPFHLTPTLYRTLRNQGN---QGAPAESR-EVLQDTVNLLFN--HPRQRNASRENLNLPEPQPATGQPRSRPLKVAGSPTGR-LAGDQGSEEAPQRPPASSATLRRQRHLNGKVSPEKESGPRQILRSLVRLSVAAFAERNPVEELTVDSPPVQQISQLLSLLHQGQFQPKPNHRGNKYLAKPG-GSRSAIPDTDGPS-ARAGGQTDPEQEEGPLDPEEDLSVKQLLEEELSSLLDPSTGLALDRLSAPDPAWMARLSLPLTTNYRDNVISPDAAAT----------EEPRTFQTFGKAEAP--ELSPTGTRLASTFVSEMSSLLEMLLEQRSSMPVEAASEALRRLS-VCGRTLSLDLATSAASGMKVQGDPGGKTGTEGKSRGSSSSSRCL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "E7F5T8-1", "uniprot_id": "E7F5T8_DANRE", "id": "E7F5T8-1", "name": "Protocadherin-12", "aln": "MLQVLLLLAALFECQVCLANN---MGSAHLTIQYRVWEEQPPGTRVGRLLDDLR-ERGETGSLENFQVVQHGHALPVTVASRDGTVSTFGRLDREELCWGTELCELAFNVLYRKGGAMHLLSVRVEVMDLNDHNPVFPSLLQEVEISETASLRMRIPLDRAADPDAGPNGLQTYTLSSNQHFALDVRS-FGGAKQAELVVTKELDRELQASLELELIAWDKGNPPKSGSTKIIVTILDSNDNSPIFEEAPSVIELAENTIRGTIVLNLRATDPDQGANGEVEYSLSKHSPLEVQRLFSIHPKTGALTLQGPLDFEEKNVYEVDIQARDLGPNGIPSHHKLQIKLQDINDNAPRIHITWTPPDSPVATVTEGAPNETFLALVMVSDADYGANGQVQVHILTGSGPFRLKQIHGDNYMIVTNGTLDREKQMEYNLTLLAQDSGDPSLSCIKHLTVHVLDENDNPPIFTKSHYRSILKENNTPGFHFLTVEAHDVDLGLSGQVSFSIRESNELGTPTAFFSVHPSSGEVTVQQSLDYEESRVYSFIVEAVDQGYPPMTSIAAVLVEIQDVNDNYPIIYEPLPKKGIALLNVPVNVDKGEIVTELG-DKAMEDNFHKHRNYSSLNKPEGFLATTIRASDPDSGLNGRLNFGITGGNPSNIFFLDKTSGEFYVNTTNATELIGRTFKLGIEVSDMGTPILSTRTTLEVTFINFRDHLKNLSHDNQAQYSFTMLLAICLGSTCLVLFLIIALAKTFCHPNKRDNRAYNCRQAESTYTRHPRRPQKHIQKTDIQLVPVLRGRR-ETSQEDEAEALSSTSPLVEKAHS---QSQFTFTPTLARMTQNQAHTEMDGNLPLTQSKILKKPGSIEWNGTLPYTSGTPCRTLQKTRNSSSSSFANSQASTLRRNKIEESKPTSMDTSQTVTSVSSNQATLRRPKTTE-KRGRMEESDQRQILRNLVRLSMAAFAE-NGSFELSSASPEVQQVSQLLSLLHQGQLQPRPNFRGNKYSHRAG---RSGAQDADWLS-TKDSGHGESEMGDMDWETGRDSPVDHLYEEGLNNLLTSDDVFS----DVPDPAWMARLSLPLSTDYHENLFIPDGPPSPDALCTMSSLDDFTSFSTFGKTLES----QPLG---GRALMSEVSSLFEMLLTQKADAQSCPPADVLYRLSAAYGRSLGLDVPVNGGAVTSRQQ---AQTSIM-------------", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : :* :* .*: * : : ::::* ** *.** :*:* :: *. . : **::* :***: : *.:* :.* *****:** : * ::*:** * *: *.::*:*:***:* **. **:****:***: ******* * *:*** * :*:**..:****** . :*:***:*.******::: ::* * *:*:******* : : *.:******** * *:. .:*: *:: **::::* *******.*****: :.** . ** *.*..*** : * .**:*:: .****:******** **.* *: **: *:*** * * :**:. * *:* *.::*:*** ..* * * ** *: : * ****: :*:.**::*.. ****: *.**::***.* .**. *.* ::: * ***.*:* **:*. *** *.:*::*::***.*** .*:**: *::* . : :. :. .:****.*:**:**: :.* * * * * * ::* :* *.: *.*** * : :* ..* * *.* **...*.:: : ..: : :.. ** ** * *.*** **. :.* .** :::*.*. *::::*.***:.*** :.* * *.* *:* *.*:. *.* *:. ***:: ::. . * . * ***. :: *::** ::*: :::********:*** * ::*:********:**:***:**.: *. : .. ....::* . . *: * :**** * :**.: :* . :: ::*:.. .: :* * .:. ..*: .. .: . :. .: . . . . ...:: .:..***** : : * . **. :****.*****:***** * * : ** ***:***********:**:**.***** :.* *. *:: : .* :.: : .. .* .*.:* ** *..** .. :: . *************:*:*::*: **...: :: :*.****: . .. * . :::**:***:**** *. ..: .* *** . **:*.**:.....: . * :.. ", "identical_positions": 455, "similar_positions": 371, "identity": "37.39%" }, { "cls_id": "homologset.agr.MGI:1855701", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q62522-1", "uniprot_id": "ZPBP1_MOUSE", "id": "Q62522-1", "name": "Zona pellucida-binding protein 1", "aln": "-----------------------------------------------------------MEALAPGRAPRGRRRAGASGSVLSPLSLAAVLLCALLRAPPAVGHLARLPRSIHLTQDSLKIVGSTHFPVSVYVMLHQKSPHVLCVTQRLRNTELVDPSFQWHGPKGKLVS-ENTTAQVTSTGSLIFQSFEETMSGVYTCFLEYKPTVEESIKNLQLKYIVYAYREPRFYYQFTARYHAAPCNSIYNISFEKKLLQILSKLVLDLSCEISLIKSECHRVKMQRAGLQNELFFTFSVASIDTEKGSKPCTDHSCEASKRLSKAKNLIERFFIQQVEVLGKRAEPLPEIYYIEGTLQMVWVNRCFPGYGINVLKHPKCPECCVVCSPGSFNPRDGTHCLQCNNSLVYGAKTCM", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8J8XCE4-1", "uniprot_id": "A0A8J8XCE4_RAT", "id": "A0A8J8XCE4-1", "name": "", "aln": "MCTQEGSQARTPPADHPSGSGGVSVGPSFRPAVRQLPAAGGRAPGNDLLRRGSAVGGVWMEALAPGPALRGRRRARASGSVLSALSLAAVVLSALLRAPPAVGHLARVPRGFRLTQDTLKIVGSTHFPVSVYVMLHQKSPHVLCVTQRLRNTELVDPSFQWHGPKGKLVS-ENTTAQVTSTGSLIFQSFEETMSGVYTCFLEYKPTVEEPIKNLQLKYIVYAYREPRFYYQFTARYHAAPCNSIYNISFEKKLLQILSKLVLDLSCEISLIKSECHRVKMQRAGLQNELFFTFSVASIDTEKGSKPCTDHSCEASKRLSKAKNLIERFFIQQVEVLGKRAEPLPEIYYIEGTLQMVWVNRCFPGYGINILKHPKCPECCVVCSPGSFNPRDGTHCLQCNNSVVYGAKTCM", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9BS86-1", "uniprot_id": "ZPBP1_HUMAN", "id": "Q9BS86-1", "name": "Zona pellucida-binding protein 1", "aln": "-----------------------------------------------------------MEAFALGPARRGRRRTRAAGSLLSRAAILLFISAFLVRVPSSVGHLVRLPRAFRLTKDSVKIVGSTSFPVKAYVMLHQKSPHVLCVTQQLRNAELIDPSFQWYGPKGKVVSVENRTAQITSTGSLVFQNFEESMSGIYTCFLEYKPTVEEIVKRLQLKYAIYAYREPHYYYQFTARYHAAPCNSIYNISFEKKLLQILSKLLLDLSCEISLLKSECHRVKMQRAGLQNELFFAFSVSSLDTEKGPKRCTDHNCEPYKRLFKAKNLIERFFNQQVEILGRRAEQLPQIYYIEGTLQMVWINRCFPGYGMNVQQHPKCPECCVICSPGSYNPRDGIHCLQCNSSLVYGAKTCL", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ***:* * * *****: *:**:** :: .: . *:*.*.:****.*:**.::**:*::****** ***..****************:***:**:******:*****:** ** ***:******:**.***:***:************* :*.***** :******::********************************:*********:********************:***:*:*****.* ****.**. *** ********** ****:**:*** **:************:********:*: :*********:*****:***** ******.*:*******:", "identical_positions": 271, "similar_positions": 58, "identity": "66.1%" }, { "cls_id": "homologset.agr.MGI:1858170", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A1BPI0-1", "uniprot_id": "OAZ3_RAT", "id": "A1BPI0-1", "name": "Ornithine decarboxylase antizyme 3", "aln": "MPCTRS--RPSLYSLSYIKRGKTRNCLYP------FWSPYAYYLYCYKYRITLREKMLPCCYRSITYKEQED---LTLRPHCCLPCSCLPYSCLPCSESLEGLQVGRSTAQEK-DHSQLKELYSAGNLTVLSADPLLHQDPVQLDFHFRLTPHSSAHWHGLL--CDHQLFLDIPFQALEQGNRESLTATLEYVEEKTNVDSVFVNFQSNHKDRGALLRAFSYMGFEVVRPDHPALPPWDNVIFMVYPLERDLGQ-PGQ--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9R109-1", "uniprot_id": "OAZ3_MOUSE", "id": "Q9R109-1", "name": "Ornithine decarboxylase antizyme 3", "aln": "MPCNRS--RPSLYSLSYIKRGKTRNYLYP------FWSPFAYYLYCYKYRITLREKMLPCCYKSITYKEQED---LTLRPHCCLPCSCLPCSCLQCSESLGGLQVGRSTAQEK-DHSQLKELYSAGNLTVLSTDPLLHQDPVQLDFHFRLTPHSSAHWHGLL--CDHRLFLDIPYQALDQGNRESLTATLEYVEEKTNVDSVFVNFQIDRKDRGALLRAFSYMGFEVVRPDHPALPPWDNVIFMVYPLERDLGH-PGQ--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9UMX2-1", "uniprot_id": "OAZ3_HUMAN", "id": "Q9UMX2-1", "name": "Ornithine decarboxylase antizyme 3", "aln": "MPCKRC--RPSVYSLSYIKRGKTRNYLYP------IWSPYAYYLYCYKYRITLREKMLPRCYKSITYKEEED---LTLQ----------PRSCLQCSESLVGLQEGKSTEQG--NHDQLKELYSAGNLTVLATDPLLHQDPVQLDFHFRLTSQTSAHWHGLL--CDRRLFLDIPYQALDQGNRESLTATLEYVEEKTNVDSVFVNFQNDRNDRGALLRAFSYMGFEVVRPDHPALPPLDNVIFMVYPLERDVGHLPSEPP", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P54361-1", "uniprot_id": "OAZ_DROME", "id": "P54361-1", "name": "Ornithine decarboxylase antizyme", "aln": "MPSNMNNKLDPVFSSGFVRREFNDSGIADGKLRTISTSSCATTMSSESYRISLGVGPLWWSDVPVHHRTDHDRASLLTGYSRKSSVDSAGGSLYEASSRASSLSSSQSDCSDLESQPDIHSLCSDDDCQEVLRQILQHDQPVQITIKLHVTEDQYTNWNTILNPVNNLLYVALPKDLPPAGSKQTFISLLEFAEEKLEVDGIVMVMPKDQPDRARLIEAFLFMGFEPLSRKAPQAPPAAINDNENYYFLYSIEE------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "**.. .::* .:::* . . : *. * : . .***:* * . .: :: :.* * * .*. .*. .:* . .: :::.* * .: : : * *::***: :::::* . ::*: :* :. *:: :* : *.:::: : **:.*** :**.:.: : :: **. *:.** :**** : . * ** * : .: . ", "identical_positions": 50, "similar_positions": 86, "identity": "19.23%" }, { "cls_id": "homologset.agr.MGI:1858171", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9JLF7-1", "uniprot_id": "TLR5_MOUSE", "id": "Q9JLF7-1", "name": "Toll-like receptor 5", "aln": "MACQLDLLIGVIFMASP-VLVISPCSSDGRIAFFRGCNLTQIPWILNTTTERLLLSFNYISMVVATSFPLLERLQLLELGTQYANLTIGPGAFRNLPNLRILDLGQSQIEVLNRDAFQGLPHLLELR--LFSCGLSSAVLSDGYFRNLYSLARLDLSGNQIHSLRLHSSFRELNSLSDVNFAFNQIFTICEDELEPLQGKTLSFFGLKLTKLFSR--VSVGWETCRNPFRGVRLETLDLSENGWTVDITRNFSNIIQGSQISSLILKHHIMGPGFGFQNIRDPDQSTFASLARSSVLQLDLSHGFIFSLNPRLFGTLKDLKMLNLAFN-KINKIGENAFYGLDSLQVLNLSYNLLGELYNSNFYGLPRVAYVDLQRNHIGIIQDQTFRLLKTLQTLDLRDNALKAIG---FIPSIQMVLLGGN---KLVHLPHIHFTANFLELSENRLENLSDLYFLLR-VPQLQFLILNQNRLSSCKAAHTPSENPSLEQLFLTENMLQLAWETGLCWDVFQGLSRLQILYLSNNYLNFLPPG-IFNDLVALRMLSLSANKLTVLSP-GSLPANLEILDISRNQLLCPDPALFSSLR------VLDITHNEFVCNCELSTFISWLNQTNVTLFGSPADVYCMYPNSLLGGSLYNISTEDCDEEEAMR--SLKFSLFILCTVTLTLFLVITLVVIKFRGICFLCYKTIQKLVFKDKVWSLEPGAYRYDAYFCFSSKDFEWAQNALLKHLDAHYSSRNRLRLCFEERDFIPGENHISNIQAAVWGSRKTVCLVSRHFLKDGWCLEAFRYAQSRSLSDLKSILIVVVVGSLSQYQLMRHETIRGFLQKQQYLRWPEDLQDVGWFLDKLSGCILK---------EEKGKKRSSSIQLRTIATIS--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O60602-1", "uniprot_id": "TLR5_HUMAN", "id": "O60602-1", "name": "Toll-like receptor 5", "aln": "MGDHLDLLLGVVLMAGP-VFGIPSCSFDGRIAFYRFCNLTQVPQVLN-TTERLLLSFNYIRTVTASSFPFLEQLQLLELGSQYTPLTIDKEAFRNLPNLRILDLGSSKIYFLHPDAFQGLFHLFELR--LYFCGLSDAVLKDGYFRNLKALTRLDLSKNQIRSLYLHPSFGKLNSLKSIDFSSNQIFLVCEHELEPLQGKTLSFFSLAANSLYSR--VSVDWGKCMNPFRNMVLEILDVSGNGWTVDITGNFSNAISKSQAFSLILAHHIMGAGFGFHNIKDPDQNTFAGLARSSVRHLDLSHGFVFSLNSRVFETLKDLKVLNLAYN-KINKIADEAFYGLDNLQVLNLSYNLLGELYSSNFYGLPKVAYIDLQKNHIAIIQDQTFKFLEKLQTLDLRDNALTTIH---FIPSIPDIFLSGN---KLVTLPKINLTANLIHLSENRLENLDILYFLLR-VPHLQILILNQNRFSSCSGDQTPSENPSLEQLFLGENMLQLAWETELCWDVFEGLSHLQVLYLNHNYLNSLPPG-VFSHLTALRGLSLNSNRLTVLSH-NDLPANLEILDISRNQLLAPNPDVFVSLS------VLDITHNKFICECELSTFINWLNHTNVTIAGPPADIYCVYPDSFSGVSLFSLSTEGCDEEEVLK--SLKFSLFIVCTVTLTLFLMTILTVTKFRGFCFICYKTAQRLVFKDHPQGTEPDMYKYDAYLCFSSKDFTWVQNALLKHLDTQYSDQNRFNLCFEERDFVPGENRIANIQDAIWNSRKIVCLVSRHFLRDGWCLEAFSYAQGRCLSDLNSALIMVVVGSLSQYQLMKHQSIRGFVQKQQYLRWPEDLQDVGWFLHKLSQQILK---------KEKEKKKDNNIPLQTVATIS--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F8W4F1-1", "uniprot_id": "F8W4F1_DANRE", "id": "F8W4F1-1", "name": "", "aln": "MAATYTLFLMLLFIWTPTVKSTSVCSTDGYFAFCMDRGLQEVPKISTYITN-VDLSKNRIAELNETSFSHLEALEVLILMHQTPGLVIRRNSFMRLSNLTSLQLDYNHHLRIDAGAFNGLSDLKNLT--LTQCGLDDSLLSGNFLKPLMSLEMLDLSRNNIRRVQPASFFLNMRRFHVLDLTFNKVKSICEEDLLNFQGKHFTLLRLSSITLQDMNEYWLGWEKCGNPFKNTSITTLDLSGNGFNVDMAKRFFDAISSTKIQSLIISNTYRIGKSSGDNSKDPDKSTFSGLKSSGIKSFDLSNSSIFSLTYSVFSYLSDLEQITLAES-QINKIENNAFLGMTNLLKLNLSKNFLGYIDFRTFQNLKGLEVLDLSYNHIWRLGSQSFQGLPNLLSLNLTGNSLGHVYTFATLPKLEKLYLGDNNIQYVYEIPNIAKHLKTLDLQFNQIASMSELYTILDEFPQIEEVVFRGNQLLYCPQDNHEVLSQNIQVLDLSFAGLQVIWSEGKCLNVFDDLHQLEVLHLSSNLLQSLPKD-IFKDLTSLLILDLSFNSLKYLPT-DVFPKTLQVLHLDYNSIYSVDPNLFSTLS------YLSLMNNDFRCDCDLKDFQTWLNQTNITFVHSIEDVTCASPEDQYMVPVVSSSIQCEDEEEERRTEKLRLVLFISCTVLIILFSASTIVYISRRGVIFKIYKKLIGKFDNKPQEEPDANGFLYDVYLCFSSRDMKWVERALLKRLDSQFSEHNTLRCCFEERDFIPGEDHLTNMRNAIQHSRKTICVVSKHFLKDGWCLETFTLAQCRMLVELKDILVVLVVGNIPQYRLLKYEQLRSFIENRSYLVWPDDGQDLEWFYDQLLHKIIRNTKVKQTNIKEKDKVDENNPEAADVQADTAV", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VJX9-1", "uniprot_id": "Q9VJX9_DROME", "id": "Q9VJX9-1", "name": "", "aln": "---MLTYLPVVWLFFALLVLRSATGQIIPLPTFCLGLSPQCTCAAEG----------NVVRFHCPDEY-----AMLLEVSEPGASLYMSYYASTELQWLPRFNISSLVKIEFDAYIFWPEKFLSDLLKTLGVQTVKTIIFRDRTLETVVTRDVLNSGNGYMETSQPE----NITTWHFGSVPGLKKFKFFSHVPELQESIFHGFDTLRDLHLSVN---VTTLPGNMLSTVNGTLKTLTIESPG-IVSFGNPLLRELQQLRNLSLALIHPFHERD------KQLQPHFFGSMTNLEEVRLASATS---SVNRSMFKGTNKLQLIKMNGNDDLMELPGEIFLDQVNLKTLDLSCNAIVTLHEDVFKGLGNLTLLDLSKNRLTNLSSTIFAPLTSLNVLRLNKNSLTAMS-----PSVFQDVVSLN----------------YIEMVNTQFYGATLLMNYEAVVCTNDEACQYKSAEWQCDPRCICWVQRSVGSLIVDCRGTSLEELP----DLPRTTLLSTVLKVGNNSLTSLPTVSEHSGYANVSGLFLSDNNLTSLGSGDQLPDNLTHLDVRGNQIQSLSDEFLLFLQEPNNTMTLSLSGNPITCGCESLSLLFFVR-TNPQRVRDIADIVCTKQKK---------SFQQMEAFELCPSYVLLISCVVGGLVIVICLLTVFYLMFQQELKIWLYNNNLCLWWVSEEELDKDK---TYDAFISYSHKDEELIS----KLLPKLESGPHPFRLCLHDRDWLVGDCIPEQIVRTVDDSKRVIIVLSQHFIDSVWARMEFRIAYQATLQDKRKRIIIILYRELEHMNGID-SELRAYLKLNTYLKWGDPLFWSKLYYAMPHNRRVL-----------KGQKKHAGPLI---------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : :: * . . :* . * : .: :* : . * : : .* * :::. :. * * :* * :. :: . :. : : *: . . :. :: ... : . .. :. : * * . . : * :. * *.: : :. : ** : : :: : *..: : : . *:. :* ..*: :.: . .: :: : * . .* *:** * : : * .* : :**. *:: : . * * .* * * *:* : *.: :. * :.: .:: . * . : . * . .: * : .: :: :* :. * * ** .. . : * *. * *. * . :* .* *.: *.: . . .: * *.: * : * *: : ::. ** *: * .. * : : * * : .: * : : . . : :. .. : **.::.:* :* . * * * : :. *:.:**:: *: :: :: *:: : ::*:**: . *. * * * : .. ::::: .: : . : . :*.::: . ** * : : : * : . ", "identical_positions": 97, "similar_positions": 225, "identity": "10.86%" }, { "cls_id": "homologset.agr.MGI:1858178", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O88623-3", "uniprot_id": "UBP2_MOUSE", "id": "O88623-3", "name": "Ubiquitin carboxyl-terminal hydrolase 2", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSQLSSTLKRYTESSRYTDAPYAKPGYGTYTPSSYGANLAASFLEKEKLGFKPVSPTSFLPRPRTYGP-------------------------------------SSILDCDRGRPLLRSDIIGSSKRSESQTRGNERPS--GSGLNGGSGFS-YGVSSNSLSYLPMNARDQGVTLSQKKSNSQSDLARDFSSLRTSDGYRTSDGYRTSEGFRIDPGNLGRSPMLARTRKELCALQGLYQAASRSEYLTDYLENYGRKGSAPQVLTQAPPPSRVPEVLSPTYRPSGRYTLWEKSKGQASGPSRSSSPGRDTMNSKS-------------------AQGLAGLRNLGNTCFMNSILQCLSNTRELRDYCLQRLYMR--DLGHTSSAHTALMEEFAKLIQTIWTSSP----NDVVSPSEFKTQIQRYAPRFMGYNQQDAQEFLRFLLDGLHNEVNRVAARP------KASPETLDHLPDEEKGRQMWRKYLEREDSRIGDLFVGQLKSSLTCTDCGYCSTVFDPFWDLSLPIAKRG-YPEVTLMDCMRLFTKEDILDGDEKPTCCRCRARKRCIKKFSVQRFPKILVLHLKRFSESRIRTSKLTTFVNFPLR--DLDLREFASENTN--------------HAVYNLYAVSNHSGTTMGGHYTAYCRSPVTGEWHTFNDSSVT-PMSSSQVRTSDAYLLFYELASPPSRM", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q5U349-1", "uniprot_id": "UBP2_RAT", "id": "Q5U349-1", "name": "Ubiquitin carboxyl-terminal hydrolase 2", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSQLSSTLKRYTESSRYTDAPYAKSGYGTYTPSSYGANLAASFLEKEKLGFKPVSPTSFLPRPRTYGP-------------------------------------SSILDCDRGRPLLRSDITGGSKRSESQTRGNERPS--GSGLNGGSGFP-YGVTSNSLSYLPMNARDQGVTLGQKKSNSQSDLARDFSSLRTSDSYRTSDGYRASDGFRIDPGNLGRSPMLARTRKELCALQGLYQAASRSEYLTDYLENYGRKGSAPQVLTQAPP-SRVPEVLSPTYRPSGRYTLWEKNKGQASGPSRSTSPGRDTMNSKS-------------------AQGLAGLRNLGNTCFMNSILQCLSNTRELRDYCLQRLYMR--DLGHTSSAHTALMEEFAKLIQTIWTSSP----NDVVSPSEFKTQIQRYAPRFVGYNQQDAQEFLRFLLDGLHNEVNRVAARP------KPSPESLDHLPDEEKGRQMWRKYLEREDSRIGDLFVGQLKSSLTCTDCGYCSTVFDPFWDLSLPIAKRG-YPEVTLMDCMRLFTKEDVLDGDEKPTCCRCRARKRCIKKFSVQRFPKILVLHLKRFSESRIRTSKLTTFVNFPLR--DLDLREFASENTN--------------HAVYNLYAVSNHSGTTMGGHYTAYCRSPVTGEWHTFNDSSVT-PMSSSQVRTSDAYLLFYELASPPSRM", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O75604-1", "uniprot_id": "UBP2_HUMAN", "id": "O75604-1", "name": "Ubiquitin carboxyl-terminal hydrolase 2", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSQLSSTLKRYTESARYTDAHYAKSGYGAYTPSSYGANLAASLLEKEKLGFKPVPTSSFLTRPRTYGP-------------------------------------SSLLDYDRGRPLLRPDITGGGKRAESQTRGTERPL--GSGLSGGSGFP-YGVTNNCLSYLPINAYDQGVTLTQKLD-SQSDLARDFSSLRTSDSYR------------IDPRNLGRSPMLARTRKELCTLQGLYQTASCPEYLVDYLENYGRKGSASQVPSQAPP-SRVPEIISPTYRPIGRYTLWETGKGQAPGPSRSSSPGRDGMNSKS-------------------AQGLAGLRNLGNTCFMNSILQCLSNTRELRDYCLQRLYMR--DLHHGSNAHTALVEEFAKLIQTIWTSSP----NDVVSPSEFKTQIQRYAPRFVGYNQQDAQEFLRFLLDGLHNEVNRVTLRP------KSNPENLDHLPDDEKGRQMWRKYLEREDSRIGDLFVGQLKSSLTCTDCGYCSTVFDPFWDLSLPIAKRG-YPEVTLMDCMRLFTKEDVLDGDEKPTCCRCRGRKRCIKKFSIQRFPKILVLHLKRFSESRIRTSKLTTFVNFPLR--DLDLREFASENTN--------------HAVYNLYAVSNHSGTTMGGHYTAYCRSPGTGEWHTFNDSSVT-PMSSSQVRTSDAYLLFYELASPPSRM", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9QLD6-1", "uniprot_id": "A0A8M9QLD6_DANRE", "id": "A0A8M9QLD6-1", "name": "Ubiquitin carboxyl-terminal hydrolase", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSRVSSTAKRYAGSS--YTSHYSS--YGSSLTPSLGSYERDKLPYKSSSSGFSSSSSSYLSSSASRSR-N----------------------------------YSSSSEPDRGRPIPRTDLLGG-RRSESLSRTPVKGY--GSGLNGGSGYSSYSYTPAPSSYLSSSPVSSSISLSRRKSVSQSDLTHDLSALGLSETSS-------------------GSGLKQSYLSRGSDVSDSYSSSRSSLGLSRSSTQEGLGSSG------------------------------LKSSSRFSSSYRSTSPVRESLNSKS-------------------AQGLVGLRNLGNTCFMNSILQCLSNTQSLRDYCLHNSHRR--DLNNNNRTHTALMEEFAKLIQTMWTSSS----SEAVSPSEFKTQIQRYAPRFVGYNQQDAQEFLRFLLDGLHNEVNRVTVRP------RGNTEDFDHLPDEEKGKKMWSKYLEREDSKIVDLFVGQLKSSLTCSECGYCSTVFDPFWDLSLPIAKKG-YGEVSLMDCMRLFTKEDVLDGDEKPTCYRCKARRRCTKKFTVQKFPKILVLHLKRFSEARIRTSKLSTFVNFPMK--DLDLREFASDRSS--------------SAVYNLYAVSNHSGTTMGGHYTAYCCNPENGEWYTYNDSRVT-PMSASQVRSSDAYVLFYERAGL----", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8M3AST8-1", "uniprot_id": "A0A8M3AST8_DANRE", "id": "A0A8M3AST8-1", "name": "Ubiquitin carboxyl-terminal hydrolase", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSPVYSSPKYATGST--LLSPYSS--YDP-CDPTLAYIVRG----QPQLSRYAPSTSRYLSPSPCLARGV----------------------------------LFFPQEPERGRAALHSEPHVG-RYSESYSRLQVKGQ--LPRINRPRGRS-----PSRNGYTCMSPLSR-----QRRSVSQSDLMRELATLEICDQG------------------------------------------------AVERTVYAVKESA------------------------------IRGRTDYSGPLYWTS-----ENSKN-------------------AQGLVGLRNLGNTCFMNSILQCLSNTHDLRDYCLRNTHRT--DLNNNCRAKAALMDEFAKLTQTIWTSAS----NEAISPSDFKMQIQKYAPRFVGYNQQDAQEFLRFLLDGLHNEVNRVTVKS------RAPVEDLDHLSEDEKGKRMWNKYLESEDSKVVDLFVGQLKSSLTCSECGFCSTVFDPFWDLSLPIAKT--SGEVSLNDCLRLFTKEDVLDGNERPTCHRCKTRRKCTKKFTIQKFPKILVLHLKRFSECRVRTSKLSTFVNFPLK--ELDLREFASDNSV--------------NAVYNLYAVSNHTGTSLGGHYTAYCRSPCTGEWYTYNDSRVS-PMSSSQVCSSDAYVLFYECATSS-RM", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q8IQ27-1", "uniprot_id": "UBP2_DROME", "id": "Q8IQ27-1", "name": "Ubiquitin carboxyl-terminal hydrolase Usp2", "aln": "MMLDIKKTRGFHKIPQASKLQSTTKTSSVVATSASSQNEVPSPGGSAGSKVGATNPVRAANQRFFLVSSYKDPTFLKAECDLAHAHVTTSKVKTTLQPHRRSRAGEDSRNNNYNTSRAPTLINMRRPSLFNGNQQPTTTNSTTINNTTSRNTTSNTSNGVLKYSVRSTTATATSTSTRNYGKLKPLNNNQTTAGVAMMNGHTNNNNNNTRNSSNINNGGNNNMQRQQQQHDDISFIDSDDPPATGGPEAGISTTKTSICYFKPITPPLQLRHEQNQVQQQEEQPQPSSSKSASHRYPRPKSTIIASAHSNFAASFEKFSGGLYRQTNGETNIESKTSSNARRYGIDSLSIKASIEKFNNLSGQKRQNPGSGSGIGPGSATASGLGGGRLSVASRSNHGSQAGGSSSNLQQRYSSDLDNIRVAAGYSSSLTRAAYRTTATMNSVSTPVAVTSELGGPISGDGGETATAMGQPTSKVTVRGAHSNRQPIECDSVVLTNKASKDATTAATPTVATATATHTPATSSVSTVTVTAAAPNSASDSTLARSGTGSSSTARSVLPPMTPTSSRYWDRDSGTSRSSIGTSSALNSSSLKHNSDDGYKTASSSRDEKSEGLCGLRNIGNTCFMNSVIQCLSHTQELTRFLRSHHGSR--SLSTK---DQQILHEFAKLIQEMWTAN-----VHTVTPMELKRAFSTKHRMYSDYNQQDAQEFLRFFLDSLHSALNSGVKGE------TLNID--DNLSDNKKADLTWEWYTRHENSLVRDLFVGQLKSTLKCTTCGNTSVTFDPFWDLSVPLPSS---SRCKLEACLDLFIREEVLDGDEMPTCAKCKTRRKCTKSFTIQRFPKYLVIHLKRFSET--RWSKLSNIVEFPTSDSELNMGSYGANSNS--------------NVHYSLYAISNHMGSTAGGHYVALCKHPVSRKWHEFNDNIVSDALSENHLVSSSAYILFYERT------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P32571-1", "uniprot_id": "UBP4_YEAST", "id": "P32571-1", "name": "Ubiquitin carboxyl-terminal hydrolase 4", "aln": "---------------MEQNIISTIRDECIRHRSKYLTIAQLTAIAEAKINEFIITGKAKDQDLSSLLDKCIDILSIYKKNSKDIKNIISCKNKGAMISSNSVMIIQLNYVYYKVIHIIVTTNIPHLSEFAKIKLHKSTSDEGNGNNNNNEFQLMNIYNTLLETLLKDENIAKIKSFIKSSIKQTKLNHEQEECNLMRTGSYITSNQLNSLISSSANSASSQMEILLIDIRSRLEFNKSHIDTKNIICLEPISFKMSYSDHDLEKKSLITSPNSEIKMFQSRNLFKFIILYTDANEYNVKQQSVLLDILVNHSFEKPISDDFTKIFILESGFPGWLKSNYGR------------------------------------QVSSSFPSNNNIKDDSVYINGNTSGLSLQHLPKMSPSIRHSMDDSMKEMLVAPTPLNHLQQQQQQQSDNDHVLKRSSSFKKLFSNYTSPNPKNSNSNLYSISSLSISSSPSPLPLHSPDPVKGNSLPINYPETPHLWKNSETDFMTNQREQLNHNSFAHIAPINTKAITSPSRTATPKLQRFPQTISMNLNMNSNGHSSATSTIQPSCLSLSNNDSLDHTDVTPTSSHNYDLDFAVGLENLGNSCYMNCIIQCILGTHELTQIFLDDSYAKHININSKLGSKGILAKYFARLVHMMYKEQVDGSKKISISPIKFKLACGSVNSLFKTASQQDCQEFCQFLLDGLHEDLNQCGSNPPLKELSQEAEARREKLSLRIASSIEWERFLTTDFSVIVDLFQGQYASRLKCKVCSHTSTTYQPFTVLSIPIPKKNSRNNITIEDCFREFTKCENLEVDEQWLCPHCEKRQPSTKQLTITRLPRNLIVHLKRFDNLLNKNNDFVIYP-FLLDLTPFWANDFDGVFPPGVNDDELPIRGQIPPFKYELYGVACHFGTLYGGHYTAYVKKGLKKGWLYFDDTKYKPVKNKADAINSNAYVLFYHRVYGV---", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . : : . . . .. . . . * . : . . . . . :. : . : * . : **.*:**:*:**.::**: *:.* .: . : . **:* : ::. ::* .:* : .***.*** :*:**.**. :* ::*. . * : : * : *** ** * *.*. *. *..::** **:*:.. . .: *: * : : *: :* * :*. *: . *.::: ::*: *::*****.: : ..: * : .: . *.**.:: * *: ****.* . * ::*. . . . .*.**:***. . ", "identical_positions": 83, "similar_positions": 125, "identity": "8.46%" }, { "cls_id": "homologset.agr.MGI:1858179", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9JI85-1", "uniprot_id": "NUCB2_RAT", "id": "Q9JI85-1", "name": "Nucleobindin-2", "aln": "MRWRTIQARYCFLLVPCVLTALEAVPIDVDKTKVHNVEPVESARIEPPDTGLYYDEYLKQVIEVLETDPHFREKLQKADIEEIRSGRLSQELDLVSHKVRTRLDELKRQEVGRLRMLIKAKLDALQDTGMNHHLLLKQFEHLNHQNPDTFESKDLDMLIKAATADLEQYDRTRHEEFKKYEMMKEHERREYLKTLSEEKRKEEEAKFAEMKRKHEDHPKVNHPGSKDQLKEVWEETDGLDPNDFDPKTFFKLHDVNNDGFLDEQELEALFTKELDKVYNPQNAEDDMIEME----EERLRMREHVMNEIDNNKDRLVTLEEFLRATEKKEFLEPDSWETLDQQQLFTEEELKEYES----------------------------------------------------------------------------------IIAIQESELKKKADEL---------------------------------------------QKQKEELQRQHDHLEAQK--QEYQQAVQQLEQKKFQQGIAPSGPAGELKFEPHT--------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P81117-1", "uniprot_id": "NUCB2_MOUSE", "id": "P81117-1", "name": "Nucleobindin-2", "aln": "MRWRIIQVQYCFLLVPCMLTALEAVPIDVDKTKVHNTEPVENARIEPPDTGLYYDEYLKQVIEVLETDPHFREKLQKADIEEIRSGRLSQELDLVSHKVRTRLDELKRQEVGRLRMLIKAKLDALQDTGMNHHLLLKQFEHLNHQNPNTFESRDLDMLIKAATADLEQYDRTRHEEFKKYEMMKEHERREYLKTLSEEKRKEEESKFEEMKRKHEDHPKVNHPGSKDQLKEVWEETDGLDPNDFDPKTFFKLHDVNNDGFLDEQELEALFTRELEKVYNPQNAEDDMIEME----EERLRMREHVMSEIDNNKDRLVTLEEFLRATEKKEFLEPDSWETLDQQQLFTEDELKEYES----------------------------------------------------------------------------------IIAIQENELKKRAEEL---------------------------------------------QKQKEDLQRQHDHLEAQK--QEYHQAVQHLEQKKLQQGIAPSGPAGELKFEPHT--------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P80303-1", "uniprot_id": "NUCB2_HUMAN", "id": "P80303-1", "name": "Nucleobindin-2", "aln": "MRWRTILLQYCFLLITCLLTALEAVPIDIDKTKVQNIHPVESAKIEPPDTGLYYDEYLKQVIDVLETDKHFREKLQKADIEEIKSGRLSKELDLVSHHVRTKLDELKRQEVGRLRMLIKAKLDSLQDIGMDHQALLKQFDHLNHLNPDKFESTDLDMLIKAATSDLEHYDKTRHEEFKKYEMMKEHERREYLKTLNEEKRKEEESKFEEMKKKHENHPKVNHPGSKDQLKEVWEETDGLDPNDFDPKTFFKLHDVNSDGFLDEQELEALFTKELEKVYDPKNEEDDMVEME----EERLRMREHVMNEVDTNKDRLVTLEEFLKATEKKEFLEPDSWETLDQQQFFTEEELKEYEN----------------------------------------------------------------------------------IIALQENELKKKADEL---------------------------------------------QKQKEELQRQHDQLEAQK--LEYHQVIQQMEQKKLQQGIPPSGPAGELKFEPHI--------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VVK7-1", "uniprot_id": "NUCB_DROME", "id": "Q9VVK7-1", "name": "Nucleobindin", "aln": "MVQNVALLGLALIAISASIVALPVTQNKKDHKEAAESSTPATADVE---TALEYERYLREVVEALEADPEFRKKLDKAPEADIRSGKIAQELDYVNHHVRTKLDEIKRREVERLRELANQAYELSNDIDRKH---LKVSQHLDHDNEHTFEIEDLRKLIQKTSDDLAEADRKRRGEFKEYEMQKEFEREAQKKEMDEESRKKFETELKEKEEKHKDHEKLHHPGNKAQLEDVWEKQDHMDKNDFDPKTFFSIHDVDSNGYWDEAEVKALFVKELDKVYQSDLPEDDMRERA----EEMERMREHYFQETDMNHDGLISIDEFMVQTNKEEFQKDPEWETIDRQQQYTHEEYLEYERRRQEEVQRLIAQGQLPPHPNMPQGYYAAPPPGGVAYQQAPPGAQLHYQHPDQVHAQQQQQYAQQQQQYAQQYQQQQYGNGQQPVQLQPNQVYQHAGQIPQQQQPVYQNQPVYQQQQPVYQQQQPVQQQQKPVQQPVQQQQQPVQQQQQPVQQQQQTVQQQQPVQQQQQTVQQQQPVQQQQQTAQQQPVAQQQIHNQSPPPVLNQQVPVQQQQKQHQESLNQQH", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P39931-1", "uniprot_id": "SS120_YEAST", "id": "P39931-1", "name": "Protein SSP120", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------MRFLRGFVFS-----------------------LAFTLYKVTATAEIGSEINVENEAP-------------------------PDGLSWEEWHMDHEHQLKDYTPETFFALHDIKKKGFLDENDILSLYGLNREEIVGAGDGMGQHDESEKIDNEMAKRVVSLIMRLLDVDDNTKITKEEYLQFAKRGNKFPDLGVGVGHHSDFELEYEIHHWNK----------------------------------------------------------------------------------FHKDKDPDVKVVHK-----------------------------------------------EDIEHELLHHEHEIEHEEEIQRGASRATVITDDELESRIELKNIPEKFKNGIF---------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . . *. *. *:: * : .* . : *. . : :*: *:*** :**:...*: ** :: :*: : ::: . .: * * *: . : * :.: :: :*:: ::: : . .:.: . * .:: : :: :. :. : ::.. :: :: . . : :. . : : ", "identical_positions": 23, "similar_positions": 82, "identity": "3.97%" }, { "cls_id": "homologset.agr.MGI:1858193", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P70627-1", "uniprot_id": "FOLH1_RAT", "id": "P70627-1", "name": "Glutamate carboxypeptidase 2", "aln": "--MWNAQQDSDSAEALGRRQRWFCAGTLVLAFTGTFIIGFLFGWFIKPSNDSTSSVSYPGMKKAFLQELKAENIKK---------------------------FLYNFTRTPHLAGTQHNFELAKQIHAQWKEFGLDLVELSDYDVLLSYPNKTHPN---------------------------YISIINE----------DGNEIFKTSLAELSPPG--YENISDVVPPYSAFSPQGTPEGDLVYVNYARTEDFFKLERVMKINCSGKIVIARYGQVFRGNKVKNAQLAGAKGIILYSDPAD----YFVPGVKSYPDGWNLPGGGVQRGNVLNLNG-AGDPLTPGYPANEYAYRHEFTEAVGLPSIPVHPIGYDDAQKLLEHMGGSAPPDSSWKGGLKVPYNVGPGFAGNFSKQKVKLHIHSYNKVTRIYNVIGTLKGAVEPDRYVILGGHRDAWVFG-GIDPQSGAAVVHEIVRTFGTLKKKGWRPRRTILFASWDAEEFGLLGSTEWAEEHSRLLQERGVAYINADSSIEGNYTLRVDCTPLMHSLVYNLTKELPSPDEGFEGKSLYDSWKEKSPSTEFIGMPRISKLGSGNDFEVFFQRLGIASGRARYTKNWKNNKVSSYPLYHSVYETYELVEKFYDPTFKYHLTVAQVRGAMVFELANSIVLPFDCQSYAVALKKHAETIYN-ISMNHPQEMKAYMISFDSLFSAVNNFTDVASKFNQRLQDLDKSN---------------PILLRILNDQLMYLERAFIDPLGLPGRPFYRHIIYAPSSHNKYAGESFPGIYDALFDINNKVDTSKAWREVKRQISIAAFTVQAAAETLREVD", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O35409-1", "uniprot_id": "FOLH1_MOUSE", "id": "O35409-1", "name": "Glutamate carboxypeptidase 2", "aln": "--MWNALQDRDSAEVLGHRQRWLRVGTLVLALTGTFLIGFLFGWFIKPSNEATGNVSHSGMKKEFLHELKAENIKK---------------------------FLYNFTRTPHLAGTQNNFELAKQIHDQWKEFGLDLVELSHYDVLLSYPNKTHPN---------------------------YISIINE----------DGNEIFKTSLSEQPPPG--YENISDVVPPYSAFSPQGTPEGDLVYVNYARTEDFFKLEREMKISCSGKIVIARYGKVFRGNMVKNAQLAGAKGMILYSDPAD----YFVPAVKSYPDGWNLPGGGVQRGNVLNLNG-AGDPLTPGYPANEHAYRHELTNAVGLPSIPVHPIGYDDAQKLLEHMGGPAPPDSSWKGGLKVPYNVGPGFAGNFSTQKVKMHIHSYTKVTRIYNVIGTLKGALEPDRYVILGGHRDAWVFG-GIDPQSGAAVVHEIVRSFGTLKKKGRRPRRTILFASWDAEEFGLLGSTEWAEEHSRLLQERGVAYINADSSIEGNYTLRVDCTPLMYSLVYNLTKELQSPDEGFEGKSLYDSWKEKSPSPEFIGMPRISKLGSGNDFEVFFQRLGIASGRARYTKNWKTNKVSSYPLYHSVYETYELVVKFYDPTFKYHLTVAQVRGAMVFELANSIVLPFDCQSYAVALKKYADTIYN-ISMKHPQEMKAYMISFDSLFSAVNNFTDVASKFNQRLQELDKSN---------------PILLRIMNDQLMYLERAFIDPLGLPGRPFYRHIIYAPSSHNKYAGESFPGIYDALFDISSKVNASKAWNEVKRQISIATFTVQAAAETLREVA", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q04609-1", "uniprot_id": "FOLH1_HUMAN", "id": "Q04609-1", "name": "Glutamate carboxypeptidase 2", "aln": "--MWNLLHETDSAVATARRPRWLCAGALVLAG-GFFLLGFLFGWFIKSSNEAT-NITPKHNMKAFLDELKAENIKK---------------------------FLYNFTQIPHLAGTEQNFQLAKQIQSQWKEFGLDSVELAHYDVLLSYPNKTHPN---------------------------YISIINE----------DGNEIFNTSLFEPPPPG--YENVSDIVPPFSAFSPQGMPEGDLVYVNYARTEDFFKLERDMKINCSGKIVIARYGKVFRGNKVKNAQLAGAKGVILYSDPAD----YFAPGVKSYPDGWNLPGGGVQRGNILNLNG-AGDPLTPGYPANEYAYRRGIAEAVGLPSIPVHPIGYYDAQKLLEKMGGSAPPDSSWRGSLKVPYNVGPGFTGNFSTQKVKMHIHSTNEVTRIYNVIGTLRGAVEPDRYVILGGHRDSWVFG-GIDPQSGAAVVHEIVRSFGTLKKEGWRPRRTILFASWDAEEFGLLGSTEWAEENSRLLQERGVAYINADSSIEGNYTLRVDCTPLMYSLVHNLTKELKSPDEGFEGKSLYESWTKKSPSPEFSGMPRISKLGSGNDFEVFFQRLGIASGRARYTKNWETNKFSGYPLYHSVYETYELVEKFYDPMFKYHLTVAQVRGGMVFELANSIVLPFDCRDYAVVLRKYADKIYS-ISMKHPQEMKTYSVSFDSLFSAVKNFTEIASKFSERLQDFDKSN---------------PIVLRMMNDQLMFLERAFIDPLGLPDRPFYRHVIYAPSSHNKYAGESFPGIYDALFDIESKVDPSKAWGEVKRQIYVAAFTVQAAAETLSEVA", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9HBA9-1", "uniprot_id": "FOH1B_HUMAN", "id": "Q9HBA9-1", "name": "Putative N-acetylated-alpha-linked acidic dipeptidase", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MGGSAPPDSSWRGSLKVSYNVGPGFTGNFSTQKVKMHIHSTNEVTRIYNVIGTLRGAVEPDRYVILGGHRDSWVFG-GIDPQSGAAVVHETVRSFGTLKKEGWRPRRTILFASWDAEEFGLLGSTEWAEDNSRLLQERGVAYINADSSIEGNYTLRVDCTPLMYSLVYNLTKELKSPDEGFEGKSLYESWTKKSPSPEFSGMPRISKLGSGNDFEVFFQRLGIASGRARYTKNWETNKFSGYPLYHSVYETYELVEKFYDPMFKYHLTVAQVRGGMVFELANSIVLPFDCRDYAVVLRKYADKIYN-ISMKHPQEMKTYSLSFDSLFSAVKNFTEIASKFSERLQDFDKSN---------------PILLRMMNDQLMFLERAFIDPLGLPDRPFYRHVIYAPSSHNKYAGESFPGIYDALFDIESKVDPSKAWGDVKRQISVAAFTVQAAAETLSEVA", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P47161-1", "uniprot_id": "VPS70_YEAST", "id": "P47161-1", "name": "Vacuolar protein sorting-associated protein 70", "aln": "MRMIQRERKREKEEGQLKERTVVNMADPDDNEAEATGLQQYSGETTRDDNEESMNDSFTLTSRNRGRSNTISSIVSGYEIMKEHMDKEKFMYLILASLLLYMGFVAAFAPRTSLSRDFRRFHSSRLTNAEVYRIYLNSLQQENRAKEHVYKYAGYMSNGASDSSTFKYTLDEFLDMGYKPKVEKYYPWIGEPVDTNVAPLENGKVVYEASMIEDRVKGDPASHARKRQKGFHQYSKNGSVTARYVFCNYG-SISDYKLLLKKNIDIEDKIHIVRSGKILPGLKVKNAELYGASSVIIYTDPFDDGKVTEENGFLHYPYGPARNPSYIRRDSVNYFSDTPGDPTTPGYPS-KDSDTEHMSPVGRVPRIPSVPMSARDVQPILERLNGRGFQIGPGSNIKDFGSFTGP----SSSIDKVHLHNELTYNIKEMSSVEVSIPGIFTEG-EIIIGAHRDSLASSSAGDANSGSAILLEIARGMSKLLKHGWKPLRPIKLISWDGERSGLLGSTDYAEAHAAILRRRALVYLNLDNAISG-TNFHCKANPLLQDVIYEAAKLTEFN--GHEDWSLFDHWKYTSN-------ATISLLDGLSSYTSFQYHLGVPAAHFQFNANDTSGAVYHS---NSVFDSPTWLEKFTNSDYKLHNTMAMFVGLTTLMLSENELARFNTHVYLKKIYNWYIAWHSNLSSAFPQDDEVNSLAKRVLDLLKVATQEDSIQFDQQNGILYKECREALPVWAFYKKIKSYIKLQRSNSKSKQIDQLFITHRGLKDREWMKYSLLAPSKFEGSVGEVLPGLHEGLADID--------RNEVIQWLTILLSQFSNVRYLLQ---", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :.* . .. . .. .** . * :**::* . ::..: .* :: * . . :*:*.***: . . . *.:**:*:: * .* :..* *.* :* *.* : ***.*. ******::** :: :*:.*.:.*:* *.:*.* .:: ...**: .:::: :* *.*. **:: *. .* . ** *.. ..: * :**:.:.: ::. * .. . :**::: : ** :. :* * *:* . * .: *::. : *: : * : : :. :* .**: :. :: * : : :*.:: : *. * *: *.: ::: ** ** .* : :: : ***..: .** :**:::.* **. :* : : : .. . * ", "identical_positions": 99, "similar_positions": 162, "identity": "11.76%" }, { "cls_id": "homologset.agr.MGI:1858195", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q6IMY8-1", "uniprot_id": "HNRPU_RAT", "id": "Q6IMY8-1", "name": "Heterogeneous nuclear ribonucleoprotein U", "aln": "MSSSPVNVKKLKVSELKEELKKRRLSDKGLKADLMDRLQAALDN-EAGGRP------AMEPGNGSLDLGGDAAGRSGAGLEQEAAAG-----AEDDEEEEGIAALDGDQMELGEENGAAGAADAGAMEEEEAASEDENGDDQGFQEGEDELGDEEEGAGDENGHGEQQSQPPAAA--QQASQQRGPGKEAAGKSSGPTSLFAVTVAPPGARQGQQQAGG-------------------DGKTEQKAGDKKRGVKRPREDHGRG------------YFEYIEENKYSRAKSPQPPVEEEDEHFDDTVVCLDTYNCDLHFKISRDRLS-ASSLTMESFAFLWAGGRASYGVSKGKVCFEMKVTEKIPVR--HLYTKDIDIHEVRIGWSLTTSGMLLGEEEFSYGYSLKGIKTCNCETEDYGEKFDENDVITCFANFETDEVELSYAKNGQDLGVAFKISKEVLADR-PLFPHVLCHNCAVEFNFGQKEKPYFPIP--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------EDCTFIQNVPLEDRVRGPKGPEEKKDCEVVMMIGLPGAGKTTWVTKHAAENPGK-YNILGTNTIMDKMMVAGFKKQMADTGKLNTLLQRAPQCLGKFIEIAARKKRNFILDQTNVSAAAQRRKMCLFAGFQRKAVVVCPKDEDYKQRTQKKAEVE-GKDLPEHAVLKMKGNFTLPEVAE-CFDEITYVELQKEEAQKLLEQYKEESKKALPPEKKQNTG----SKKSNKNKSGKNQFNR------GGGHR-----------GRGGFNMRGGNFRGGAPGNRGGYNR----------------RGNMPQRGGGGG-SGGIGYPYPRGPVFPGRGGYSNRG-------------NYNRGGMP----------------------------NRGNYNQNFRGRGNN---RGY-------------------------------------------------------------KNQSQGYNQ-WQQGQFWGQKPWSQHYHQGYY----------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8VEK3-1", "uniprot_id": "HNRPU_MOUSE", "id": "Q8VEK3-1", "name": "Heterogeneous nuclear ribonucleoprotein U", "aln": "MSSSPVNVKKLKVSELKEELKKRRLSDKGLKADLMDRLQAALDN-EAGGRP------AMEPGNGSLDLGGDAAGRSGAGLEQEAAAG-----AEDDEEEEGIAALDGDQMELGEENGAAGAADAGAMEEEEAASEDENGDDQGFQEGEDELGDEEEGAGDENGHGEQQSQPPAAAAQQQPSQQRGAGKEAAGKSSGPTSLFAVTVAPPGARQGQQQAGG-------------------DGKTEQKGGDKKRGVKRPREDHGRG------------YFEYIEENKYSRAKSPQPPVEEEDEHFDDTVVCLDTYNCDLHFKISRDRLS-ASSLTMESFAFLWAGGRASYGVSKGKVCFEMKVTEKIPVR--HLYTKDIDIHEVRIGWSLTTSGMLLGEEEFSYGYSLKGIKTCNCETEDYGEKFDENDVITCFANFETDEVELSYAKNGQDLGVAFKISKEVLADR-PLFPHVLCHNCAVEFNFGQKEKPYFPIP--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------EDCTFIQNVPLEDRVRGPKGPEEKKDCEVVMMIGLPGAGKTTWVTKHAAENPGK-YNILGTNTIMDKMMVAGFKKQMADTGKLNTLLQRAPQCLGKFIEIAARKKRNFILDQTNVSAAAQRRKMCLFAGFQRKAVVVCPKDEDYKQRTQKKAEVE-GKDLPEHAVLKMKGNFTLPEVAE-CFDEITYVELQKEEAQKLLEQYKEESKKALPPEKKQNTG----SKKSNKNKSGKNQFNR------GGGHR-----------GRGGFNMRGGNFRGGAPGNRGGYNR----------------RGNMPQRGGGGG-SGGIGYPYPRGPVFPGRGGYSNRG-------------NYNRGGMP----------------------------NRGNYNQNFRGRGNN---RGY-------------------------------------------------------------KNQSQGYNQ-WQQGQFWGQKPWSQHYHQGYY----------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q00839-1", "uniprot_id": "HNRPU_HUMAN", "id": "Q00839-1", "name": "Heterogeneous nuclear ribonucleoprotein U", "aln": "MSSSPVNVKKLKVSELKEELKKRRLSDKGLKAELMERLQAALDDEEAGGRP------AMEPGNGSLDLGGDSAGRSGAGLEQEAAAGGDEEEEEEEEEEEGISALDGDQMELGEENGAAGAADSGPMEEEEAASEDENGDDQGFQEGEDELGDEEEGAGDENGHGEQQPQPPATQ-QQQPQQQRGAAKEAAGKSSGPTSLFAVTVAPPGARQGQQQAGGKKKAEGGGGGGRPGAPAAGDGKTEQKGGDKKRGVKRPREDHGRG------------YFEYIEENKYSRAKSPQPPVEEEDEHFDDTVVCLDTYNCDLHFKISRDRLS-ASSLTMESFAFLWAGGRASYGVSKGKVCFEMKVTEKIPVR--HLYTKDIDIHEVRIGWSLTTSGMLLGEEEFSYGYSLKGIKTCNCETEDYGEKFDENDVITCFANFESDEVELSYAKNGQDLGVAFKISKEVLAGR-PLFPHVLCHNCAVEFNFGQKEKPYFPIP--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------EEYTFIQNVPLEDRVRGPKGPEEKKDCEVVMMIGLPGAGKTTWVTKHAAENPGK-YNILGTNTIMDKMMVAGFKKQMADTGKLNTLLQRAPQCLGKFIEIAARKKRNFILDQTNVSAAAQRRKMCLFAGFQRKAVVVCPKDEDYKQRTQKKAEVE-GKDLPEHAVLKMKGNFTLPEVAE-CFDEITYVELQKEEAQKLLEQYKEESKKALPPEKKQNTG----SKKSNKNKSGKNQFNR------GGGHR-----------GRGGFNMRGGNFRGGAPGNRGGYNR----------------RGNMPQRGGGGGGSGGIGYPYPRAPVFPGRGSYSNRG-------------NYNRGGMP----------------------------NRGNYNQNFRGRGNN---RGY-------------------------------------------------------------KNQSQGYNQ-WQQGQFWGQKPWSQHYHQGYY----------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "E7F3J2-1", "uniprot_id": "E7F3J2_DANRE", "id": "E7F3J2-1", "name": "", "aln": "--MSAINVKKLKVNELKDELKKRSLSDKGLKADLMSRLQAALDEEALSG---------TNGSERRYEDGGDPAGKDLE----EDPVG------ESMEEEE----------EDG-GNAEAEHDDIMEEEEEDAGVEMDKSD-------EDALLKDDDGDDDEDEEMEKFDEDDVAL-----------DKGDADK---------------------------------------------DKKDEQK---NKKGVKRRRDEHGRA------------YFEFIEERKYSRAKSPQPPLEEEDEEFDDTTVCLDTYNCDLHFKVSRDRYS-ASSLTMESFAYLWAGGRGSYGVDKGKACFEMKVIEKIPVK--HISSKGIEDHDVLVGWSLANSSYLLGEEAYSYAFSMTAKKTSNAVTEDYGETFDENDVVGCFINFDGAEVEISFSKNGEDLGKAFTVSKDELKGK-PLFPHVLCHNCAVEFNFGQQESPFFAQP--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------DGFTLLQQIPVHDRIRGPKGPENKKDCEVIVVVGLPGSGKTEWVTKHTEANPGK-YNILGTDTILEKMMISTLKRQMKDVTKLLEISLRAPLFLGKFIEIAARKKRNYILDQTNVSASARKRKMCLFAGFQRKAVVVCPTDEEYKKRTLKKAETD-GKKVPEQAIRKTKRIYSLPVEGD-CFSEVLYVELQKEEVAKLLEQYKEDSK-ICSLEPKPIQAGVQSKRRSSKGRGGKNMFNR---GGEGGLAQRG--------GGRGGFPHRGNFMGVPIPR--GGFRRPPIDFLPP-----HAFREVFSRGSFSRG--MVMPNRGGAPRPGPGRGNMGNRGGAMHR-------EHMGHGGG-------------------------------GNFNQKFRGRGGN--NRGFK-------------------------------------------------------NGNFRMSKAQAFNESWQQG-FCNRKPWSHPYSPSYY----------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q5RHQ7-1", "uniprot_id": "Q5RHQ7_DANRE", "id": "Q5RHQ7-1", "name": "Heterogeneous nuclear ribonucleoprotein U", "aln": "--MSEINVKKLKVNELKDELKKRQLSDKGLKAELMERLQAALDAEAQAQEEETTAPGTTEGSKVGNDADGNGVAAEQEGTGEEEPEG------ENMEAEE----------QNGEGDEAAGQDDEMGEEEEEDDDDDDAGE-------EIDKALDDE-DDEEDDIIDKIDVED----------------GDADK---------------------------------------------DSSADQK---NKKGVKRRREDHGRG------------YFEFIEESKYSRTKSPQPPLEEVDEEFDDTLVCLDPYNCDLHFKVSRNRYS-ASSLTMESFAHLWAGGRASYGVNKGKVCFEMKVTEKTPIK--HLNSKIMDFHDVHIGWSLANGCLSLGEEEFSYSYSDKGKKASNCVTEDYGEGFDENDVIGCFINFEADEVEISFSKNGNDLGVAFKVNKESLADR-ALFPHVLCHNCTVEFNFGQNETPFFPKL--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------EDFTFMQQIPLEERIRGPKGPVAKKDCEVIVMVGLPGSGKTTWVVKHVEENPGK-YNILSTNTVLEKLMINSVKRQNKDITKLMAISQRVPFYLGKLIEIAARKKRHYILDQTNVSSAAQRRKMCLFAGFQRKAVVVFPTDENLKERAQKKAEAD-GKDIPEHALLKMKALYTLPEQGD-CFSEVTYVELQKDEASKLLEKYKEESKNALPPEKKPNQGPPTPKRGSRRGRGQKNQFNRSGGGGGGGGQGNR--------GGRGGFQPRGNYRALLAPPRVSGFDRRPRGYILPPPPPPPVYRGYPSRDGYNRGGSGGMQSRGMSPRGGQMRGNMASRGGGMSRGGHANRGGNMHRGGGQG------------------------GPNHRGHYQQKFHGRGGHQQNRGG--------------------------------------------------------YGNKNSSFAQAFNQSWQQG-FWNQKPWNQQYHPGYY----------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "E1JGL8-1", "uniprot_id": "E1JGL8_DROME", "id": "E1JGL8-1", "name": "", "aln": "--MDVAKLEKMKVVDLRNELQSRGLDTKGVKAVLVERLRAYVEGGAGDGEN-----APVTPSRRQRRTRSMSRSPSPVQAAPVAAEPVLDTLEEEEQPEDKTVPQPEPESEQPAAEPEPEQSEPEEAEPAAAVTEDTTVNQAVNEESQPEPEEFDEKSETDDKQETIEEAVPAVVPQNEVADEPMEEDHDAAPEEQEPTQTEEPVEEKPAESTVAEHQSNGDSQKMDVDEEDSAAPKTAEETEPAAKPEDQPPERRKRSHSRSKSRSRSGSRSSKHRGSVGDKRESKAAAEERTVPEDEPTIEENKVGLSWLDSDLHLRIDPTTFASAKPLTSEIYSLIWSGARANYGVREGKVCFEVRLSEESVPENSHYFRDEPHVRGFRVGFSMPKSSLLLGEAEHSFGYCETGRKATQSEFTDYGKPYQLDDVIGCYLDLESEPCTINYTLNGEDLGVAFEFEKSILGEEGALFPHIVTKGYEYLVNFSDTEQLLVNAERPTRKRRKPRKDEDKDKDDDKDDNDGEKWKVLDEATADDDEVEKKDEDGKASSEKDEEEAEDPEKAKEDEAAPKTETEAETKVEAPAEAAKPESEATEASETAETSTEKSSETAAVSNGDAAAEQANDEKASEDKKPSENNDEEDEDGPSPNKRPKTDGDSEKAESEKEKDRSQTTEDEYEDVVPEPRDTAALLEGYVLIGLVPVEKLVSGPQRVGSRKECEVILLVGLPGAGKTHWAHKHVAENADKRYELIGPDAFISKMTIDGASRKTVHKGRWDKVYEICLNSLAALEDIAMKRRRNFILDQTNVYASAQRRKMKGFNDFKRIAVVCIPSEDELKRRIAEKEEKGNAFTVKESTINNLRANFTLPSLEFGWFDDINYTELTGDEAKSEVKKYNEKGKKAIDAERSRDKRSRGSRDNYRRDDRNRNRYNDDRRRDYGGQRHESRWSDSRRGGGGGGYSSNSGGGGSRGYDNRRNYNSGSGGQQNWVQ---NSRRSGYDDRGYGGGGSGSRGYDNRNRGYAGGSGGGGGGGGGGGGGGGQQNWMQNNRRSGYDDRGYGSSRDYRDRDRGNDRSRMGSNDRNRGSSQSSYRSGGGTHQQRDFRPGHRDTKEDSRGGYERSAGQSLPKYGNNTAVGGGYDQYKQQGGAPGGGKASLSGKWSTYSQHHQQQQAPQHQQTGIWQTQQQSQQYQQPQQAAAGQQQYWAYNQMQTGYGNQQAWQSADPQQQQQWMSWWQQQQQGSGGAAAGNASGGSGVNVGGGAGNNDGGAANHYWSQYSYSTQSNAGADKK", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . :::*:** :*::**:.* *. **:** *:.**:* :: .. . . . . *. : *: : : . : * : : : :: :: * . : :.: :* : .*.*. : : : : *:: : : .: * : :::. * *. :.***:::. : *..** * :: :*:*.*..*** :**.***::: *: . * . . : . :*:*:... *** .*:.:. .. *: :. ***: :: :**: *: ::: :.:: **:*** ** ..*. * . .****:: :. .**.: * . : .:: :*:.. : **: :*:***::::****:*** *. **. *..* *:::..::.:.*: : .:: . : : *. : :** :::*::******* ::*::*** * .*:* *** *.::: *.* :* * . : * :: : : ::** *.:: *.** :*. . :::*:*..* * . :. :* :* ** * **: ... .: * . . * *. .. * : : . * :..::. *. *. * ** : : .: * ", "identical_positions": 153, "similar_positions": 244, "identity": "11.93%" }, { "cls_id": "homologset.agr.MGI:1858196", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O88599-1", "uniprot_id": "MYBPH_RAT", "id": "O88599-1", "name": "Myosin-binding protein H", "aln": "-----------------MTGKATPEASVSTSEGTAPEPAKVPTPEPSGQVAASESTGQEQAPEPQKQPQAQDPAAHEAPATPATTKPE-----------APSEDVPSAPLQLTLEDVSHSSLTVSWEPPEDLGSWGSRAMCWSSVREGASEWVPVNPRPVMVTQQTVRNLALGDKFFLRVTAVNSAGAGPPAVLDQPVHIQEITEAPKIRVPRHLRQTYIRQVGESVNLQIPFQGKPKPQASWTHNGHALDSQRVNVRSGDQDSILFIRSAQRSDSGRYELTVRLEGLEAKAAIDILVIEKPGPPSSIKLLDVWGCNAALEWMPPQDTGNTELLGYTVQKADKKTGQWFTVLERYHPTTCTVSDLIIGNSYSFRVFSENLCGLSDLATTTKELAHIHK-----------AAITAKPREFTERDFSEPPSFTQPVADRTSTPGYSTQLFCSVRASPKPKIIWMKNKMSIQGDPKYRAVSEQGVCTLEIRKPSPFDSGVYTCKAINVLGEPAVDCRLEVKASATH------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P70402-1", "uniprot_id": "MYBPH_MOUSE", "id": "P70402-1", "name": "Myosin-binding protein H", "aln": "-----------------MTGKATSEASVSTPEETAPEPAKVPTTEPSGEVAASESTGQEQAPEPQK-PQAQDPAAPAASAMPAATKPE-----------PPSEDVPSAPLRLTLEDVSHSSLTVSWEPPEKLGKLGLQGYVLEFCREGASEWVPVNPRPVMVTQQTVRNLALGDKFFLRVTAVSSAGAGPPAVLDQPVHIQEITEAPKIRVPRHLRQTYIRQVGESVNLQIPFQGKPKPQVSWTHNGHALDNQRVNVRSGDQDSILFIRSAQRADSGRYELTVHLEGLEAKASIDILVIEKPGPPSSIKLLDVWGCNAALEWTPPQDTGNTELLGYTVQKADKRTGQWFTVLERYHPTTCTISDLIIGNSYSFRVFSENLCGLSDLATTTKELAHIHK-----------ADITAKPREFIERDFSEAPSFTQPLADHTSTPGYSTQLFCSVRASPKPKIIWMKNKMDIQGDPKYRAVSEQGVCTLEIRKPSPFDSGVYTCKAINVLGEASVDCRLEVKASATH------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q13203-1", "uniprot_id": "MYBPH_HUMAN", "id": "Q13203-1", "name": "Myosin-binding protein H", "aln": "-----------------MMEKNTSEGPACSPEETASESAKVPTAEPPGEVAVSESTREEQVPKPQA-------PAPQAPTASTATKPA-----------PPSEDVPSAPLLLTLDDVSSSSVTVSWEPPERLGRLGLQGYVLELCREGASEWVPVSARPMMVTQQTVRNLALGDKFLLRVSAVSSAGAGPPAMLDQPIHIRENIEAPKIRVPRHLRQTYIRQVGETVNLQIPFQGKPKPQATWTHNGHALDSQRVSMRTGDQDSILFIRSAQRSDSGRYELTVRVEDLEAKAVIDILVIEKPGPPSSIRLLDVWGCNAALQWTPPQDTGNTELLGYMVQKADKKTGQWFTVLERYHPTTCTISDLIIGNSYSFRVFSENLCGLSTSATVTKELAHIQK-----------ADIAAKPKGFIERDFSEAPSFTQPLADHTSTPGYSTQLFCSVRASPKPKIIWMKNKMEIQGNPKYRALSEQGVCTLEIRKPSPFDSGVYTCKAINVLGEASVDCRLEVKASAAH------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M6Z3P8-1", "uniprot_id": "A0A8M6Z3P8_DANRE", "id": "A0A8M6Z3P8-1", "name": "Myosin-binding protein H", "aln": "MPAKPAPIKKSAKKAAEKEEKPAAPAPVPETAPVEAPPAEDPPVEAAAPAAVEETTPAPEAPVAEG-PAEETAPAADAPAEAAPAEPAPVEEPPKAPTPPPPAVPPSAPQGLSVDDVNDTSVTLKWRSPENIG-SGLDGYAVEYCKEGSSEWVVANTELVTSNRHAIRGLTTGDMLNIRVVAVNAGGRSEPVVLPQPIPVREVMDRPRIRMPRALRSKYIRHAGEQINLVIPFSGKPKPVISWTKNGQPLDTKKVNVRNSDKDSILFIRKAERDDSGSYEMSVKVDSFEDKTTLIIQIVDLPGPPVSVKLVDSWGFNAALEWTPPKDNGNTEITGYTVQKADKKTGEWFTVLEHFHRLNVTVTDLVMGNVYTFRVFSENMVGRSETAAVTKDAARIKKTVPAEVVVPLSVGIVYKPLEYKEHDFSEAPKFTAPLKDRAATVGYTAKLLCAVRGSPKPKIEWLKNQMLLGDDPKFRQINNQGVCSLEIRKPSSFDGGVYTCRAKNALGEATVACKLEVKQVTIQEEKDKK", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * :. ... . . . .*: *. *... .*..*:* :.* .: .* *.: .:.::* .*. **** *:::**. :*:*:.*..** :* * . . :**:**** .... : .::::*.*: ** : :** **.:.* . *.:* **: ::* : *:**:** **..***:.** :** ***.***** :**:**:.**.::*.:*..*:*******.*:* *** **::*:::.:* *: : * ::: **** *::*:* ** ****:* **:*.****: ** ******:**:******::* . *::**::** *:*******: * * *:.**: *:*:* . *. ** : *:****.*.** *: *:::* **:::*:*:**.****** *:**:* : .:**:* :.:****:*******.**.*****:* *.***.:* *:**** : : ", "identical_positions": 216, "similar_positions": 163, "identity": "40.83%" }, { "cls_id": "homologset.agr.MGI:1858197", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9WUC8-1", "uniprot_id": "PLRG1_RAT", "id": "Q9WUC8-1", "name": "Pleiotropic regulator 1", "aln": "-MVEEVQKHSVHTL----VFRSLKRTHDMFVADNGKPVPLDEESHKRKMAIKLRNEYGPVLHMPTSK-ENLKEKGPQNAPDSYPHKQYPANQGQDVEYLVTGTHPYPPGPGVALTADTKIQRMPSESAAQSLAVALPSQTRVDANRTAPAGSEYRHPGASDRSQPTAMNSMIMETSNTKNSALMAKKAPTMPKPQWHPPWKLYRVISGHLGWVRCIAVEP-GNQWFVTGSADRTIKIWDLASGKLKLSLTGHISTVRGVIVSTRSPYLFSCGEDKQVKCWDLEYNKVIRHYHGHLSAVYGLDLHPTIDVLVTCSRDSTARIWDVRTKASVHTLSGHTNAVATVRCQAAEPQIITGSHDTTIRLWDLVAGKTRVTLTNHKKSVRAVVLHPLHYTFASGSPDNIKQWKFPDGGFIQNLSG-HNAIINTLAVNTDGVLVSGADNGTMHLWDWRTGYNFQRVHAAVQPGSLDSESGIFACAFDRSESRLLTAEADKTIKVYREDETATEETHP-VSWKPEIIKRKRF", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q922V4-1", "uniprot_id": "PLRG1_MOUSE", "id": "Q922V4-1", "name": "Pleiotropic regulator 1", "aln": "-MVEEVQKHSVHTL----VFRSLKRTHDMFVADNGKPVPLDEESHKRKMAIKLRNEYGPVLHMPTSK-ENLKEKGPQNATDSYPHKQYPANQGQDVEYLVTGTHPYPAGPGVALTADTKIQRMPSESAAQSLAVALPSQTRVDANRTGPAGSEYRHPGASDRSQPTAMNS-IMETGNTKNSALMAKKAPTMPKPQWHPPWKLYRVISGHLGWVRCIAVEP-GNQWFVTGSADRTIKIWDLASGKLKLSLTGHISTVRGVIVSTRSPYLFSCGEDKQVKCWDLEYNKVIRHYHGHLSAVYGLDLHPTLDVLVTCSRDSTARIWDVRTKASVHTLSGHTNAVATVRCQAAEPQIITGSHDTTIRLWDLVAGKTRVTLTNHKKSVRAVVLHPLLYTFASGSPDNIKQWKFPDGGFIQNLSG-HNAIINTLAVNADGVLVSGADNGTMHLWDWRTGYNFQRVHAAVQPGSLDSESGIFACAFDRSESRLLTAEADKTIKVYREDETATEETHP-VSWKPEIIKRKRF", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O43660-1", "uniprot_id": "PLRG1_HUMAN", "id": "O43660-1", "name": "Pleiotropic regulator 1", "aln": "-MVEEVQKHSVHTL----VFRSLKRTHDMFVADNGKPVPLDEESHKRKMAIKLRNEYGPVLHMPTSK-ENLKEKGPQNATDSYVHKQYPANQGQEVEYFVAGTHPYPPGPGVALTADTKIQRMPSESAAQSLAVALPLQTKADANRTAPSGSEYRHPGASDRPQPTAMNSIVMETGNTKNSALMAKKAPTMPKPQWHPPWKLYRVISGHLGWVRCIAVEP-GNQWFVTGSADRTIKIWDLASGKLKLSLTGHISTVRGVIVSTRSPYLFSCGEDKQVKCWDLEYNKVIRHYHGHLSAVYGLDLHPTIDVLVTCSRDSTARIWDVRTKASVHTLSGHTNAVATVRCQAAEPQIITGSHDTTIRLWDLVAGKTRVTLTNHKKSVRAVVLHPRHYTFASGSPDNIKQWKFPDGSFIQNLSG-HNAIINTLTVNSDGVLVSGADNGTMHLWDWRTGYNFQRVHAAVQPGSLDSESGIFACAFDQSESRLLTAEADKTIKVYREDDTATEETHP-VSWKPEIIKRKRF", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VYQ9-1", "uniprot_id": "Q9VYQ9_DROME", "id": "Q9VYQ9-1", "name": "Pleiotropic regulator 1", "aln": "MAMEDVQKHSVHTL----IFRSLKRTHDLFVSNQGNLPEIDERLEKLRRSIKAKDGYGLVLDKVAKIGEARKASGAQTPGD----KTLAITDG--------SATDAASGAGSLVKYNAGAR--PAEKTAP-----LVTGTHTSLVRASLANS------NADMSANGAIAS---------HLQLIPKKAPSIPKPKWHAPWKLSRVISGHLGWVRCIAVEP-GNEWFATGAGDRVIKIWDLASGKLKLSLTGHVSTVRGVAVSTKHPYLFSCGEDRQVKCWDLEYNKVIRHYHGHLSAVYSLALHPTIDVLATSGRDSTARIWDMRTKANVHTLTGHTNTVASVVAQATNPQIITGSHDSTVRLWDLAAGKSVCTLTNHKKSVRSIVLHPSLYMFASASPDNIKQWRCPEGKFVQNISG-HTSIVNCMAANSEGVLVSGGDNGTMFFWDWRTGYNFQRFQAPVQPGSMDSEAGIFAMCFDQSGSRLITAEADKTIKVYKEDDEASEESHP-INWRPDLLKRRKF", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q12417-1", "uniprot_id": "PRP46_YEAST", "id": "Q12417-1", "name": "Pre-mRNA-splicing factor PRP46", "aln": "---MDGNDHKVENLGDVDKFYSRIRWNNQFSYMATLPPHLQSEMEGQKSLLMRYDTY-------------RKESSS------------------------------FSGEGKKVTLQHVPTDFSEASQAV------ISKKDHDTHASAFVNKIF----QPEVAEELIVNR---------YEKLLSQ------RPEWHAPWKLSRVINGHLGWVRCVAIDPVDNEWFITGSNDTTMKVWDLATGKLKTTLAGHVMTVRDVAVSDRHPYLFSVSEDKTVKCWDLEKNQIIRDYYGHLSGVRTVSIHPTLDLIATAGRDSVIKLWDMRTRIPVITLVGHKGPINQVQCTPVDPQVVSSSTDATVRLWDVVAGKTMKVLTHHKRSVRATALHPKEFSVASACTDDIRSWGLAEGSLLTNFESEKTGIINTLSINQDDVLFAGGDNGVLSFYDYKSGHKYQSLATREMVGSLEGERSVLCSTFDKTGLRLITGEADKSIKIWKQDETATKESEPGLAWNPNLS-AKRF", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : :.*.*..* * * * :: * ::.. . : : : * * ... .* * :. : . . * . . :. .. .: . : *:.: :*:**.**** ***.********:*::* .*:** **: * .:*:****:**** :*:**: ***.* ** : ***** .**: ******* *::**.*:****.* : :***:*::.*..***. ::**:**: * ** **...: * . ..:**:::.* *:*:****:.***: .**:**:***: .*** : .**...*:*:.* .:* :: *:.. :..*:* :: * :.**.:*.***.: ::*:::*:::* . : **::.* .::. **:: **:*.****:**::::*: *::*:.* : *.*:: ::*", "identical_positions": 160, "similar_positions": 164, "identity": "30.59%" }, { "cls_id": "homologset.agr.MGI:1858199", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q62447-1", "uniprot_id": "CCNC_MOUSE", "id": "Q62447-1", "name": "Cyclin-C", "aln": "MAGNFWQSSHYLQWILDKQDLLKERQKDLKFLSE----------------------------------EEYWKLQIFFTNVIQALGEHLKLRQQVIATATVYFKRFYARYSLKSIDPVLMAPTCVFLASKVEEFGVVSNTRLIAATTSVLKTRFSYAFPKEFPYRMNHILECEFYLLELMDCCLIVYHPYRPLLQYVQDMGQEDVLLPLA-------WRIVNDTYRTDLCLLYPPFMIALACLHVACVVQQKDA---------------------------RQWFAELSVDMEKILEIIRVILKLYEQWKNFDERKEMATILSKMPKPKPPPNSEGEQGPNGSQNSSYSQS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P39947-1", "uniprot_id": "CCNC_RAT", "id": "P39947-1", "name": "Cyclin-C", "aln": "MAGNFWQSSHYLQWILDK-----ERQKDLKFLSE----------------------------------EEYWKLQIFFTNVIQALGEHLKLRQQVIATATVYFKRFYARYSLKSIDPVLMAPTCVFLASKVEEFGVVSNTSLIAATTSVLKTRFSYASPKEFPYRMNHILECEFYLLELMDCCLIVYHPYRPLLQYVQDMGQEDVLLPLA-------WRIVNDTYRTDLCLLYPPFMIALACLHVACVVQQKDA---------------------------RQWFAELSVDMEKILEIIRVILKLYEQWKNFDERKEMATILSKMPKPKPPPNSEGEQGPNGSQNSSYSQS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P24863-1", "uniprot_id": "CCNC_HUMAN", "id": "P24863-1", "name": "Cyclin-C", "aln": "MAGNFWQSSHYLQWILDKQDLLKERQKDLKFLSE----------------------------------EEYWKLQIFFTNVIQALGEHLKLRQQVIATATVYFKRFYARYSLKSIDPVLMAPTCVFLASKVEEFGVVSNTRLIAAATSVLKTRFSYAFPKEFPYRMNHILECEFYLLELMDCCLIVYHPYRPLLQYVQDMGQEDMLLPLA-------WRIVNDTYRTDLCLLYPPFMIALACLHVACVVQQKDA---------------------------RQWFAELSVDMEKILEIIRVILKLYEQWKNFDERKEMATILSKMPKPKPPPNSEGEQGPNGSQNSSYSQS", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P25008-1", "uniprot_id": "CCNC_DROME", "id": "P25008-1", "name": "Cyclin-C", "aln": "MAGNFWQSSHSQQWILDKPDLLRERQHDLLALNE----------------------------------DEYQKVFIFFANVIQVLGEQLKLRQQVIATATVYFKRFYARNSLKNIDPLLLAPTCILLASKVEEFGVISNSRLISICQSAIKTKFSYAYAQEFPYRTNHILECEFYLLENLDCCLIVYQPYRPLLQLVQDMGQEDQLLTLS-------WRIVNDSLRTDVCLLYPPYQIAIACLQIACVILQKDAT--------------------------KQWFAELNVDLDKVQEIVRAIVNLYELWKDWKEKDEIQMLLSKIPKPKPPPQR-----------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P47821-1", "uniprot_id": "SSN8_YEAST", "id": "P47821-1", "name": "RNA polymerase II holoenzyme cyclin-like subunit", "aln": "MSGSFWTSTQRHHWQYTKASLAKERQKLWLLECQLFPQGLNIVMDSKQNGIEQSITKNIPITHRDLHYDKDYNLRIYCYFLIMKLGRRLNIRQYALATAHIYLSRFLIKASVREINLYMLVTTCVYLACKVEECPQYIRTLVSEART---------LWPEFIPPDPTKVTEFEFYLLEELESYLIVHHPYQSLKQIVQVLKQPPFQITLSSDDLQNCWSLINDSYINDVHLLYPPHIIAVACLFITISIHGKPTKGSSLASAASEAIRDPKNSSSPVQIAFNRFMAESLVDLEEVMDTIQEQITLYDHWDKYHEQWIKFLLHTLYLRPASAI-------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*:*.** *:: :* * ***: : :: :: *: :* **.:*::** .:*** :*:.** : *::.*: ::..**: **.**** .: : .: :* .:: * ****** ::. ***::**:.* * ** : * :.*: * ::**: .*: *****. **:*** :: : * : .:::** **:::: : :: :.**: *..:.*: : : :* .. ", "identical_positions": 76, "similar_positions": 88, "identity": "21.65%" }, { "cls_id": "homologset.agr.MGI:1858200", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D4A834-1", "uniprot_id": "D4A834_RAT", "id": "D4A834-1", "name": "", "aln": "MKQPLILSLLLLGMVSAFHLDSAHPHLETSKREEDLNPEADGSREQGRELVLTQGIMQTEGEEVEGSEHQDVFEDGEAMESEPDALDEDSVCPREEDTAHFQGTPGCKSCRYVLVRTPKTFHKAQKLCRRCYRGNLASIHTFGFNFQVQSLARKINQSIVWIGGVLRRWLFWKNFCWTDGSRWDFGYWAPGQPGNGEGHCVTLCAKGGHWRRASCKSRLPFICSF", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9JL95-1", "uniprot_id": "PRG3_MOUSE", "id": "Q9JL95-1", "name": "Proteoglycan 3", "aln": "MKQPLILSFLLLGMVSAFHLETAH--LENPKREESLKQEADGSREQGRELALTQETKQTEGEEVEGSQHQDIFEDEEAMESDPDALNKDSACPKEEDTTHFQGTPGCKSCNYVLVRTPETFDKAQRVCRRCYRGNLASVHSYSFNYQIQNLARKINQSIVWIGGILRGW-FWKKFCWMDGSCWDFGYWAPGQPGSGGGHCVTLCTKGGHWRRASCKSHLPFICSF", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9Y2Y8-1", "uniprot_id": "PRG3_HUMAN", "id": "Q9Y2Y8-1", "name": "Proteoglycan 3", "aln": "MQCLLLLPFLLLGTVSALHLENDAPHLESLETQADLGQDLDSSKEQERDLALTEEVIQAEGEEVKASACQDNFEDEEAMESDPAALDKDFQCPREEDIVEVQGSPRCKICRYLLVRTPKTFAEAQNVCSRCYGGNLVSIHDFNFNYRIQCCTSTVNQAQVWIGGNLRGWFLWKRFCWTDGSHWNFAYWSPGQPGNGQGSCVALCTKGGYWRRAQCDKQLPFVCSF", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*: *:*.:**** ***:**:. **. : : .* : *.*:** *:*.**: *:*****:.* ** *** *****:* **::* **:*** ...**:* ** *.*:*****:** :**.:* *** ***.*:* :.**:::* : .:**: ***** ** * :**.*** *** *:*.**:*****.* * **:**:***:****.*..:***:***", "identical_positions": 124, "similar_positions": 59, "identity": "55.11%" }, { "cls_id": "homologset.agr.MGI:1858201", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P97846-1", "uniprot_id": "CNTP1_RAT", "id": "P97846-1", "name": "Contactin-associated protein 1", "aln": "-----------MMSLRLFSILLAAVVS------GAQGWGYYGCNEELVGPLYARSLGASSYYGLFTTARFARLHGISGWSPRIGDPNPWLQIDLMKKHRIRAVATQGAFNSWDWVTRYMLLYGDRVDSWTPFYQQGHN-ATFFGNVNDSAVVRHDLHYHFTARYIRIVPLAWNPR--GKIGLRLGIYGCPYTSNILYFDGDDAISYRFQRGASQSLWDVFAFSFKTEEKDGLLLHTEGSQGDYVTLELQGAHLLLHMSLGSSPIQPRPGHTTVSAGGVLNDLSWHYVRVDRYGREANLTLDGYVHRFVLNGDFERLNLENEIFIGGLVGAARKNLAYRHNFRGCIENVIYNRINIAEMAVQRHSR-ITFEG---NVAFRCLDPVPHPINFGGPHNFVQVPGFPRRGRLAVSFRFRTWDLTGLLLFSRLGDGLGHVELMLSEGQVNVSIAQTGRKKLQFAAG-YRLNDGFWHEVNFVAQENHAVISIDDVEGAEVRVSYPLLIRTGTSYFFGGCPKPASRWGCHSNQTAFHGCMELLKVDG-QLVNLTLVEFRKLGYFAEVLFDTCGITDRCSPNMCEHDGRCYQSWDDFICYCELTGYKGVTCHEPLYKESCEAYR-LSGKY-SGNYTIDPDGSGPLKPFVVYCDIREN-RAWTVVRHDRLWTTRVTGSSMDRPFLGAIQYWNASWEEVSALANASQHCEQWIEFSCYNSRLLNTAG----GYPYSFWIGRNEEQHFYWGGSQPGIQRCACGLDQSCIDPALHCNCDADQPQWRTDKGLLTFVDHLPVTQVVIGDTNRSSSE--AQFFLRPLRCYGDRNSWNTISFRTG-AALRFPPIRANHSLDVSFYFRTSAPSGVFLENMGGPFCQWRRPYVRVELNTSRDVVFAFDIGNGDENLTVHSDDFEFNDDEWHLVRAEINVKQARLRVDHRPWVLRPMPLQTYIWLEYDQPLYVGSAELKRRPFVGCLRAMRLNGVTLNLEGRAN-ASEGTFPNCTGHCTHPRFPCFHGGRCVERYSYYTCDCDLTAFDGPYCNHDIGGFFETGTWMRYNLQSALRSAAQEFSHMLSRPVPGYEPGYIPGYDTPGYVPGYHGPGYRLPDYPRPGRPVPGYRGPVYNVTGEEVSFSFSTSSAPAVLLYVSS-FVRDYMAVLIKEDGTLQLRYQLGTSPYVYQLTTRPVTDGQPHSVNITRVYR--NLFIQVDYFPLTEQKFSLLVDSQLDSPKALYLGRVMETGVIDPEIQRYNTPGFSGCLSGVRFNNVAPLKTHFRTPRPMTAELAEAMRVQGELSESNCGAMPRLVSEVPPELDP-WYLPPDFPYYHDDGWIAILLGFLVAFLLLGLVGMLVLFYLQNHRYKGSYHTNEPKATHDSHPGGKAPLPPSGPAQAPAPTPAPTQVPT----PAPAPASGPGPRDQNLPQILEESRSE", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O54991-1", "uniprot_id": "CNTP1_MOUSE", "id": "O54991-1", "name": "Contactin-associated protein 1", "aln": "-----------MMSLRLFSILLATVVS------GAWGWGYYGCNEELVGPLYARSLGASSYYGLFTTARFARLHGISGWSPRIGDPNPWLQIDLMKKHRIRAVATQGAFNSWDWVTRYMLLYGDRVDSWTPFYQKGHN-ATFFGNVNDSAVVRHDLHYHFTARYIRIVPLAWNPR--GKIGLRLGIYGCPYTSSILYFDGDDAISYRFQRGASQSLWDVFAFSFKTEEKDGLLLHTEGSQGDYVTLELQGAHLLLHMSLGSSPIQPRPGHTTVSLGGVLNDLSWHYVRVDRYGRDANFTLDGYAHHFVLNGDFERLNLENEIFIGGLVGAARKNLAYRHNFRGCIENVIYNRINIAEMAVMRHSR-ITFEG---NVAFRCLDPVPHPINFGGPHNFVQVPGFPRRGRLAVSFRFRTWDLTGLLLFSHLGDGLGHVELMLSEGQVNVSIAQTGRKKLQFAAG-YRLNDGFWHEVNFVAQENHAVISIDDVEGAEVRVSYPLLIRTGTSYFFGGCPKPASRWGCHSNQTAFHGCMELLKVDG-QLVNLTLVEFRKLGYFAEVLFDTCGITDRCSPNMCEHDGRCYQSWDDFICYCELTGYKGVTCHEPLYKESCEAYR-LSGKY-SGNYTIDPDGSGPLKPFVVYCDIREN-RAWTVVRHDRLWTTRVTGSSMDRPFLGAIQYWNASWEEVSALANASQHCEQWIEFSCYNSRLLNTAG----GYPYSFWIGRNEEQHFYWGGSQPGIQRCACGLDQSCVDPALHCNCDADQPQWRTDKGLLTFVDHLPVTQVVVGDTNRSNSE--AQFFLRPLRCYGDRNSWNTISFHTG-AALRFPPIRANHSLDVSFYFRTSAPSGVFLENMGGPFCRWRRPYVRVELNTSRDVVFAFDIGNGDENLTVHSDDFEFNDDEWHLVRAEINVKQARLRVDHRPWVLRPMPLQTYIWLVYDQPLYVGSAELKRRPFVGCLRAMRLNGVTLNLEGRAN-ASEGTFPNCTGHCTHPRFPCFHGGRCVERYSYYTCDCDLTAFDGPYCNHDIGGFFETGTWMRYNLQSALRSAAREFSHMLSRPVPGYEPGYVPGYDTPGYVPGYHGPGYRLPEYPRPGRPVPGYRGPVYNVTGEEVSFSFSTNSAPAVLLYVSS-FVRDYMAVLIKEDGTLQLRYQLGTSPYVYQLTTRPVTDGQPHSVNITRVYR--NLFIQVDYFPLTEQKFSLLVDSQLDSPKALYLGRVMETGVIDPEIQRYNTPGFSGCLSGVRFNNVAPLKTHFRTPRPMTAELAEAMRVQGELSESNCGAMPRLVSEVPPELDP-WYLPPDFPYYHDDGWIAILLGFLVAFLLLGLVGMLVLFYLQNHRYKGSYHTNEPKATHDSHPGGKAPLPPSGPAQAPAPTPAPTQLPTPAPAPAPAPASGPGPRDQNLPQILEESRSE", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P78357-1", "uniprot_id": "CNTP1_HUMAN", "id": "P78357-1", "name": "Contactin-associated protein 1", "aln": "-----------MMHLRLFCILLAAVS-------GAEGWGYYGCDEELVGPLYARSLGASSYYSLLTAPRFARLHGISGWSPRIGDPNPWLQIDLMKKHRIRAVATQGSFNSWDWVTRYMLLYGDRVDSWTPFYQRGHN-STFFGNVNESAVVRHDLHFHFTARYIRIVPLAWNPR--GKIGLRLGLYGCPYKADILYFDGDDAISYRFPRGVSRSLWDVFAFSFKTEEKDGLLLHAEGAQGDYVTLELEGAHLLLHMSLGSSPIQPRPGHTTVSAGGVLNDQHWHYVRVDRFGRDVNFTLDGYVQRFILNGDFERLNLDTEMFIGGLVGAARKNLAYRHNFRGCIENVIFNRVNIADLAVRRHSR-ITFEG---KVAFRCLDPVPHPINFGGPHNFVQVPGFPRRGRLAVSFRFRTWDLTGLLLFSRLGDGLGHVELTLSEGQVNVSIAQSGRKKLQFAAG-YRLNDGFWHEVNFVAQENHAVISIDDVEGAEVRVSYPLLIRTGTSYFFGGCPKPASRWDCHSNQTAFHGCMELLKVDG-QLVNLTLVEGRRLGFYAEVLFDTCGITDRCSPNMCEHDGRCYQSWDDFICYCELTGYKGETCHTPLYKESCEAYR-LSGKT-SGNFTIDPDGSGPLKPFVVYCDIREN-RAWTVVRHDRLWTTRVTGSSMERPFLGAIQYWNASWEEVSALANASQHCEQWIEFSCYNSRLLNTAG----GYPYSFWIGRNEEQHFYWGGSQPGIQRCACGLDRSCVDPALYCNCDADQPQWRTDKGLLTFVDHLPVTQVVIGDTNRSTSE--AQFFLRPLRCYGDRNSWNTISFHTG-AALRFPPIRANHSLDVSFYFRTSAPSGVFLENMGGPYCQWRRPYVRVELNTSRDVVFAFDVGNGDENLTVHSDDFEFNDDEWHLVRAEINVKQARLRVDHRPWVLRPMPLQTYIWMEYDQPLYVGSAELKRRPFVGCLRAMRLNGVTLNLEGRAN-ASEGTSPNCTGHCAHPRLPCFHGGRCVERYSYYTCDCDLTAFDGPYCNHDIGGFFEPGTWMRYNLQSALRSAAREFSHMLSRPVPGYEPGYIPGYDTPGYVPGYHGPGYRLPDYPRPGRPVPGYRGPVYNVTGEEVSFSFSTSSAPAVLLYVSS-FVRDYMAVLIKDDGTLQLRYQLGTSPYVYQLTTRPVTDGQPHSINITRVYR--NLFIQVDYFPLTEQKFSLLVDSQLDSPKALYLGRVMETGVIDPEIQRYNTPGFSGCLSGVRFNNVAPLKTHFRTPRPMTAELAEALRVQGELSESNCGAMPRLVSEVPPELDP-WYLPPDFPYYHDEGWVAILLGFLVAFLLLGLVGMLVLFYLQNHRYKGSYHTNEPKAAHEYHPGSKPPLPTSGPAQVPTPTAAPNQAPASAPAPAPTPAPAPGPRDQNLPQILEESRSE", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8N7TDM7-1", "uniprot_id": "A0A8N7TDM7_DANRE", "id": "A0A8N7TDM7-1", "name": "", "aln": "------------MDIRILAPSLLFFL-------AFQPCSSRPCLDPLISPLYASSFHASSRYNFFYSAHFAKLYGSSGWSPSTRDRQPWMQIDLGRKYRIMAIATQGTFNSYDWVTKYMVLYGDRFDSWTPYVMKGGN-MTLPGNWNYYQVKRNVFHYAFTAKHLRIYPMGWNTENGGKIGLRVEFYGCPYDSYVMNFEGDDMVAYSFPRGRMRTLQDHYALNFKTLEKDGILLHSEGLQGDSITLELKTGRLYLHISLGSSTVHNTNGMTTMMLGNLLDTQHWHYVTIKRFGRELNFTLDSQTETTILNGEFQHLDLDKKIYVGGVIEKDMPHLPGKVNFRGCMENVFINGINIIYMTQNQEPE-IRLAPKKKKMHYMCRDLLWKPMTFAGPNNYLQLPGFFRKNRLAVKFKFRSWDYTGLLMFTRFADELGSLELGLSEGQVNVTLMQPGNKRLRFAAG-YRLNDGFWHTVDLTAKDNLLTITIDEDESSPLKITNPFMVRTGDRYFFGGCPKTNNTARCVTKLSRFHGCMQQIFIDD-EPVDIDVMLQRKWGRYAEILLGTCGITDRCSPNPCEHEGRCIQSWNDFLCVCNNTGYKGEVCHNSVYRESCEAYR-LNGKYWSGNYTIDPDLSGPLKPFTVYCNMLQ--KTWTVIEHNRMKSTKVSGSTIDRPYIGDVQYVNASWDEVTALANTSLYCEQWIEFSCYKSRLLNTPH----GRPYTYWIGRHNESHEYWGGAFPESGKCGCAVNQTCTDSKYWCNCDADYRQWHSDKGYLSFRDHLPIRRLVIGDTNRTGSE--AQYSVGALYCHGDRSIWNTIAFTKP-TYLTFPTFKPGTSADITFHFRTYRTYGVFVEASD----DHLRNFLRVELNSTTEVVFIFMVGDGIRNVTLRSPK-ALNDNEWHYVEAEINVKLARLKVDFLPPAIHKFPGQTYITMDFTQPLLVGAANHTLRPFLGCLRGLRMNGVPVDLEGKVD-ESAGIRRNCTGACLNASIPCRNGGQCIDGYASYACDCNNTGFDGYYCHLDIGAFFDVGAWLRYDVRKEPISFDAWWANFWIEP---------------------HWHNFTLG----------------YNTTTDDIEFSFSTLQAPAVLLYISS-FSNDYIAVLLKKDGTLSMRYRLGIISYKFKMTDRNMADGFPHFVNITRHNY--TVWTQVDYMDPWIEKLVPGEIPRFDSPKSIFLGRVMEVGGVDYEIQRHNSPGFMGCISGVRYNIFAPLKAYFRPN-----VTNPPVTTQGYVVESNCGAFPPVLGYVPWEDDP-WFTGLFFYYIHDD-VTPPWMTLIVTVSLMLLFLILYGLYIYLYRYKGSYHTNEPKQLES--PSSARPLTDTLRKDR-----------------------------KNLPEIQEESPNE", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q94887-1", "uniprot_id": "NRX4_DROME", "id": "Q94887-1", "name": "Neurexin-4", "aln": "MRPPRSNTKAAFSSLQFGLLCLLLLVNNGIKSVQADAFTDYFSDYDCNQPLMERAVLTATSSLTERGPDKARLNGNAAWTPVENTYNHFLTLDLGDPRMVRKIATMGRMHTDEFVTEYIVQYSDDGEFWRSYVNPTSEPQMFKGNSDGNSIHYNVFEVPIIAQWVRINPTRWHDR----ISMRVELYGCDYISENLYFNGTGLVRYDLRREPITSTKESIRFRFKTAFANGVMMYSRGTQGDYYALQLKDNKMVLNLDLGSR------VMTSLSVGSLLDDNVWHDVVISRNQRDIIFSVDRVIVRGRIQGEFTRLNLNRELYLGGVPNVQEG-LIVQQNFSGCLENIYFNSTNFIRVMKDSTELGEGYLFTRVNTIYACPSPPIYPVTFTTRSSFVRLKGYENSQRLNVSFYFRTYEETGVMLHHDFYSG-GYLKVFLEFGKVKIDLKVKDKARIILDNYDDQFNDGKWHSFVISIEKNRLILNIDQ---RPMTTTKSMQVATGAQYYIAGG----------KDKNGFVGCMRLISVDGNYKLPQDWVKGEEVCCGDDVVVDACQMIDRCNPNPCQHKGLCHQNSREFFCDCGHTGYAGAVCHTSNNPLSCLALKNVQHVQQRVNLNLDVDGSGPLEPFPVTCEFYSDGRVITTLSHSQEHTTTVDGFQEPGSFEQSIMYD-ANQLQIEALLNRSHSCWQRLSYSCRSSRLFNSPSEAGNFRPFSWWISRHNQPMDYWAGALPGSRKCECGILGKCHDPTKWCNCDSNSLEWMEDGGDIREKEYLPVRAVKFGDTGTPLDEKMGRYTLGPLRCEGDDLFSNVVTFRIADASINLPPFDMGHSGDIYLEFRTTQENSVIFHATG------PTDYIKLSLNGGNKLQFQYQAGSGPLGVNV-GTSYHLNDNNWHTVSVERNRKEARLVVDGSIKAEVREPPGPVRALHLTSDLVIGATTEYRDGYVGCIRALLLNGKMVDLKEYSKRGLYGISTGCVGRCESN--PCLNNGTCIERYDGYSCDCRWSAFKGPICADEIGVNLRSSSIIRYEFEGSFR-----------------------------------------------------------STIAENIRVGFTTTIPKGFLLGFSSNLTGEYLTIQISNSGHLRCVFDFGFERQEIIFPKKHFGLGQYHDMHFMRKNGGSTVVLKVDNYEPVEYNFDIKASADAQFNNIQYMYIGKNE---------SMTDGFVGCVSRVQFDDIYPLKLMFQQN-----PPKNVKSLGTQLTEDFCGVEPVTHPPIEIETRPPPLVDEEKLRKAYNEVDSVLLACLLVILFLLLILMFFLIGRYLHRHKGDYLTHEDQGADGADDPDDAVLHSTTGHQVR-----------------------------KRTEIFI-----", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ::: * . . ** :. ::: . *:* * :.*:* : :: :** : :** * ::: ::**.*:: *.* : * .: : : ** : : : :. : *: :** * *: . *.:*: :*** * : : *:* . : * : * : : : *** :*:::::.* *** :*:*: :: *::.*** *:: *.:*: ** * :.* *: :::* ::*:* :*:*: ::::**: * : ** **:**: * *: : : : * . *:.* .:::: *: . ** *.* **::: **:::. : . * ::: *. *:*:: : .. :: : ::*** ** . : :.* :.**: : : .: : ** *::.* .. . * ***. : :*. : : .. :::..:* : ***.** *:*.* * *. :*:* * *** * .** . ** * : :. * .:* * ****:** * *:: . :. *.: *.: :* * * .: : * *. :: ** * * * * :.:** .***:*:. *:::**.*::: **.*: * :* *.: .* *. ****:: :* * * : ::**: : .***. . .* .:: : .* * ** *.::* : : :*.: . * *: : *** .*:.. . ::::.** .: * : *.* .:.: . . :**::** * .* * * *** ** . * . : . * :*:: ::**:*.: :** ::*: . * .*.* * ** :.* *:: * *:*** :.*.* * :** : .: :**:.. .. ::: ..*:* . ..** .** : :*::: :...* * : :* :. : . * * ::: * .: :** :: . : : :: : : ** **:* *::: . *** *: : *. **. * : * * : . : ::.. :: *. :: : :*:**.* *:* : . . * : : : .:* ", "identical_positions": 285, "similar_positions": 385, "identity": "19.99%" }, { "cls_id": "homologset.agr.MGI:1858202", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P62491-1", "uniprot_id": "RB11A_HUMAN", "id": "P62491-1", "name": "Ras-related protein Rab-11A", "aln": "MGTRDD--EYDYLFKVVLIGDSGVGKSNLLSRFTRNEFNLESKSTIGVEFATRSIQVDGKTIKAQIWDTAGQERYRAITSAYYRGAVGALLVYDIAKHLTYENVERWLKELRDHADSNIVIMLVGNKSDLRHLRAVPTDEARAFAEKNGLSFIETSALDSTNVEAAFQTILTEIYRIVSQKQMSD-------RRENDMSPSNNVVPIHVPPTTENKPK-VQCCQNI", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P62494-1", "uniprot_id": "RB11A_RAT", "id": "P62494-1", "name": "Ras-related protein Rab-11A", "aln": "MGTRDD--EYDYLFKVVLIGDSGVGKSNLLSRFTRNEFNLESKSTIGVEFATRSIQVDGKTIKAQIWDTAGQERYRAITSAYYRGAVGALLVYDIAKHLTYENVERWLKELRDHADSNIVIMLVGNKSDLRHLRAVPTDEARAFAEKNGLSFIETSALDSTNVEAAFQTILTEIYRIVSQKQMSD-------RRENDMSPSNNVVPIHVPPTTENKPK-VQCCQNI", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P62492-1", "uniprot_id": "RB11A_MOUSE", "id": "P62492-1", "name": "Ras-related protein Rab-11A", "aln": "MGTRDD--EYDYLFKVVLIGDSGVGKSNLLSRFTRNEFNLESKSTIGVEFATRSIQVDGKTIKAQIWDTAGQERYRAITSAYYRGAVGALLVYDIAKHLTYENVERWLKELRDHADSNIVIMLVGNKSDLRHLRAVPTDEARAFAEKNGLSFIETSALDSTNVEAAFQTILTEIYRIVSQKQMSD-------RRENDMSPSNNVVPIHVPPTTENKPK-VQCCQNI", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q5U3E1-1", "uniprot_id": "Q5U3E1_DANRE", "id": "Q5U3E1-1", "name": "small monomeric GTPase", "aln": "MGTRDD--EYDYLFKVVLIGDSGVGKSNLLSRFTRNEFNLESKSTIGVEFATRSIQVDGKTVKAQIWDTAGQERYRAITSAYYRGAVGALLVYDIAKHLTYENVERWLKELRDHADSNIVIMLVGNKSDLRHLRAVPTDEARAFAEKNGLSFLETSALDSTNVETAFQTILTEIYRIVSQKQMSD-------RRDNDMSPSNNVVSIQVQP-TENKPK-MQCCQSI", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "O18335-1", "uniprot_id": "O18335_DROME", "id": "O18335-1", "name": "", "aln": "MGARED--EYDYLFKVVLIGDSGVGKSNLLSRFTRNEFNLESKSTIGVEFATRSIEVDGKTIKAQIWDTAGQERYRAITSAYYRGAVGALLVYDIAKHLTYENVERWLRELRDHADQNIVIMLVGNKSDLRHLRSVPTDEAKLFAERNGLSFIETSALDSTNVETAFQNILTEIYRIVSQKQIRD-------PPEGDVIRPSNVEPIDVKPTVTADVR-KQCCQ--", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P38555-1", "uniprot_id": "YPT31_YEAST", "id": "P38555-1", "name": "GTP-binding protein YPT31/YPT8", "aln": "MSSEDYGYDYDLLFKIVLIGDSGVGKSNLLSRFTKNEFNMDSKSTIGVEFATRTLEIDGKRIKAQIWDTAGQERYRAITSAYYRGAVGALIVYDISKSSSYENCNHWLSELRENADDNVAVGLIGNKSDLAHLRAVPTEESKTFAQENQLLFTETSALNSENVDKAFEELINTIYQKVSKHQMDLGDSSANGNANGASAPNGPTISLTPTPNENKKANGNNCC---", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P51996-1", "uniprot_id": "YPT32_YEAST", "id": "P51996-1", "name": "GTP-binding protein YPT32/YPT11", "aln": "MSNEDYGYDYDYLFKIVLIGDSGVGKSNLLSRFTTDEFNIESKSTIGVEFATRTIEVENKKIKAQIWDTAGQERYRAITSAYYRGAVGALIVYDISKSSSYENCNHWLTELRENADDNVAVGLIGNKSDLAHLRAVPTDEAKNFAMENQMLFTETSALNSDNVDKAFRELIVAIFQMVSKHQVDLSGSGTN-NMGSNGAPKGPTISLTPAPKEDKKKKSSNCC---", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*. .: :** ***:****************** :***::************:::::.* :****************************:****:* :*** ::** ***::**.*:.: *:****** ***:***:*:: ** .* : * *****:* **: **. :: *:: **::*: . . . .: * . . :** ", "identical_positions": 119, "similar_positions": 51, "identity": "52.65%" }, { "cls_id": "homologset.agr.MGI:1858203", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9WTL2-1", "uniprot_id": "RAB25_MOUSE", "id": "Q9WTL2-1", "name": "Ras-related protein Rab-25", "aln": "MGN-RTDEDYNFVFKVVLIGESGVGKTNLLSRFTRNEFSHDSRTTIGVEFSTRTVMLGTAAVKAQIWDTAGLERYRAITSAYYRGAVGALLVFDLTKHQTYAVVERWLKELYDHAEATIVVMLVGNKSDLSQAREVPTEEACMFAENNGLLFLETSALDSTNVELAFQTVLKEIFAKVSKQKQNS------------TRTSAITLGNAQAGQDPGPGEKRACCISL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P57735-1", "uniprot_id": "RAB25_HUMAN", "id": "P57735-1", "name": "Ras-related protein Rab-25", "aln": "MGN-GTEEDYNFVFKVVLIGESGVGKTNLLSRFTRNEFSHDSRTTIGVEFSTRTVMLGTAAVKAQIWDTAGLERYRAITSAYYRGAVGALLVFDLTKHQTYAVVERWLKELYDHAEATIVVMLVGNKSDLSQAREVPTEEARMFAENNGLLFLETSALDSTNVELAFETVLKEIFAKVSKQRQNS------------IRTNAITLGSAQAGQEPGPGEKRACCISL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q1LVA5-1", "uniprot_id": "Q1LVA5_DANRE", "id": "Q1LVA5-1", "name": "Ras-related protein Rab-25", "aln": "MG---TDLAYNFVFKVVLIGESGVGKSNLLSRFTKNEFNHDSRTTIGVEFSTRSVQVDSITIKAQIWDTAGLERYRAITSAYYRGAVGALLVYDITKHLTYESVERWLKELYDHADPHIVVMLVGNKNDLATVRTVPTEEAKDFADANGLLFMETSALESTNVESAFLEVLTAIHQKVASKEVTR------------GSISAVTLGQTHGPSRE-FQESRSCCKNS", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "F1Q9W8-1", "uniprot_id": "F1Q9W8_DANRE", "id": "F1Q9W8-1", "name": "Ras-related protein Rab-25", "aln": "MG---SDEAYNFVFKVVLIGESGVGKSNLLSRFTKNEFSHDSRTTIGVEFSTRTVQLNGLTIKAQIWDTAGLERYRAITSAYYRGAVGALLVYDISKHLTYESAERWLKELYDHADPHIVVMLVGNKSDLAAVRSVPTEDAKDFAEKNGLLFMETSALESVNVEAAFNTVLTEIHKKVNSKEVTR------------GSISAVTLSQPKTPAET-QEEKKTCCKNL", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P38555-1", "uniprot_id": "YPT31_YEAST", "id": "P38555-1", "name": "GTP-binding protein YPT31/YPT8", "aln": "MSSEDYGYDYDLLFKIVLIGDSGVGKSNLLSRFTKNEFNMDSKSTIGVEFATRTLEIDGKRIKAQIWDTAGQERYRAITSAYYRGAVGALIVYDISKSSSYENCNHWLSELRENADDNVAVGLIGNKSDLAHLRAVPTEESKTFAQENQLLFTETSALNSENVDKAFEELINTIYQKVSKHQMDLGDSSANGNANGASAPNGPTISLTPTPNENKKANGNNCC---", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P51996-1", "uniprot_id": "YPT32_YEAST", "id": "P51996-1", "name": "GTP-binding protein YPT32/YPT11", "aln": "MSNEDYGYDYDYLFKIVLIGDSGVGKSNLLSRFTTDEFNIESKSTIGVEFATRTIEVENKKIKAQIWDTAGQERYRAITSAYYRGAVGALIVYDISKSSSYENCNHWLTELRENADDNVAVGLIGNKSDLAHLRAVPTDEAKNFAMENQMLFTETSALNSDNVDKAFRELIVAIFQMVSKHQVDLSGSGTN-NMGSNGAPKGPTISLTPAPKEDKKKKSSNCC---", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*. *: :**:****:*****:******* :**. :*::******:**:: : :********* ******************:*:*::* :* ::**.** ::*: :.* *:***.**: * ***::: ** * :** *****:* **: ** :: *. * .:. .. *:. . : ** ", "identical_positions": 98, "similar_positions": 50, "identity": "43.36%" }, { "cls_id": "homologset.agr.MGI:1858204", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9WUL6-1", "uniprot_id": "M3K14_MOUSE", "id": "Q9WUL6-1", "name": "Mitogen-activated protein kinase kinase kinase 14", "aln": "-MAVMEVACPGTPGSAVGQQKELAKAKEKTQSLGKKQSCIFKLEAVEKSPVFCGKWEILNDVITKGTAKDGSEGGPPAIS----IIAQAECENSQEFSPTFSERIFIAGSQQYSQSESLDQIPNNVAHATEGKMARVCRRGKRHG------------------------KARKKRRKKRSKSLAQAGVALAKPLPRTPEQESCTIPVQEDESPLGNLYARNVSQFTKPLGGPGLGHLCFKKQDEGLRPVLPRPELHKLISPLQCLNHVWKLHHPQATGPRPHPTHPFPYSGMPHPFPFYPLEPWKPYMLDSAVLDKLAGVSGQRPLPGPPHLSQLAHGDSQKPLPGPHLESSCPSRGALEKVPVEEYLVHALQGSVSSGQ-AHSLASLAKTWSSGSAKLQRLGPETEDNEGVLLTEKLKPVDYEYREEVHWMTHQPRVGRGSFGEVHRMKDKQTGFQCAVKKVRLEVFRVEELVACAGLSSPRIVPLYG-------AVREGPWVNIFMELLEGGSLGQLIKQMGC-LPEDRALYYLGQALEGLEYLHTRRILHGDVKADNVLLSSDGSRAALCDFGHALCLQPDGLGKSLLTGDYIPGTETHMAP-EVVMGKPCDAKVDIWSSCCMMLH----------------------------MLNGCHPWTQYFRGPLCLKIASEPPPIREIPPSCAPLTAQAIQEG---------------------------LRKEPVHRASAMELRRKVG-----------------------------KALQEVGGLKSPWKG----EYKEPRPPPQDQATCHQTLPTPPRENPP----------AKANTDGAPEPQPPLPPEPPEPSKAPALNLSKEESGTWEPLPLSSLDPATAKG--------PSFPDRRATLPELELQQ---------LEIELFLNSLSQPFSLEEQEQILSCLSIDSLSLSDDSEKNPS-KASQSSRDTLSSGVHSWNSQAEARTCSCSTALARGRPTDIPSYFNGVKVQIQSLNGEHLHIREFHRVKVGDIATGISSQIPATAFSLVTKDGQPVCYDMEVPDSGIDLQCTLAPDG---------SFAWTWRVKHGQLENRP-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D3ZTD1-1", "uniprot_id": "D3ZTD1_RAT", "id": "D3ZTD1-1", "name": "Mitogen-activated protein kinase kinase kinase 14", "aln": "-MAVMEVACPGTPGSAVGQQKEFAKAKEKTQSPGKKQSCIFQLEAVEKSPVFCGKWEILNDVITKGTAKEGSEGGPPAIS----IIAQAECENSQEFSPTFSERIFIAGSQQYSQSESLDQIPNNVAHATEGKMARVCRKGKRHS------------------------KARKKRRKRRSKSLAQAGVALAKPLPRTPEQESCTIPVQEDESPLGNLYARNVSQFTKPLKGPGLGHLCFKKQDEGLRPVLPRPELHKLISPLQCLNHVWKLHHPQATGPLPHPTHPFPFSRMPHPFPFYPLEPWRPYTLNPAFLDKLAAVSGQRPLPGPPHLSKPAYRDSQKPLPGPHLESSCLSREALEKVPAEEYLVHALQGSVSSGQ-AHSLASLAKTWSSGSSKLQRFSPETEDNEGVLLTEKLKPVDYEYREEVHWMTHQPRVGRGSFGEVHRMKDKQTGFQCAVKKVRLEVFRAEELIACAGLSSPRIVPLYG-------AVREGPWVNIFMELLEGGSLGQLIKQKGC-LPEDRALYYLGQALEGLEYLHTHRVLHGDVKADNVLLSSDGSRAALCDFGHALCLQPDGLGKSLLTGDYIPGTETHMAP-EVVLGKPCDAKVDIWSSCCMMLH----------------------------MLNGCHPWTQYFRGPLCLKIASEPPPVREIPPSCTPLTAQAIQEG---------------------------LRKEPIHRASAMELRRKVG-----------------------------KALQEVGGLKSPWKG----EYKEPRPPPQDQAPCPQTLHTLPRENPP----------AKANTDGAPERQPPLPPEPPEPNKAPALNLSKEESGTWEPLPLSSLDPAPAKG--------PSLPDRRATFPELELQQ---------LEIELFLNSLSQPFSLEEQEQILSCLSIDSLSLSEDSEKNPS-KASQSSRDTLSSGVHSWSSQAEARSSSCSMALARGRPTDIPSYFNGVKVQIQSLNGEHLHIREFHRVKVGDIATGISSQIPATAFSLVTKDGQPVCYDMEVPDSGIDLQCTLAPDG---------SFAWAWRVKHGQLENRP-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q99558-1", "uniprot_id": "M3K14_HUMAN", "id": "Q99558-1", "name": "Mitogen-activated protein kinase kinase kinase 14", "aln": "-MAVMEMACPGAPGSAVGQQKELPKAKEKTPPLGKKQSSVYKLEAVEKSPVFCGKWEILNDVITKGTAKEGSEAGPAAIS----IIAQAECENSQEFSPTFSERIFIAGSKQYSQSESLDQIPNNVAHATEGKMARVCWKGKRRS------------------------KARKKRKKKSSKSLAHAGVALAKPLPRTPEQESCTIPVQEDESPLGAPYVRNTPQFTKPLKEPGLGQLCFKQLGEGLRPALPRSELHKLISPLQCLNHVWKLHHPQDGGPLPLPTHPFPYSRLPHPFPFHPLQPWKPHPLES-FLGKLACVDSQKPLPDP-HLSKLACVDSPKPLPGPHLEPSCLSRGAHEKFSVEEYLVHALQGSVSSGQ-AHSLTSLAKTWAARGSRSREPSPKTEDNEGVLLTEKLKPVDYEYREEVHWATHQLRLGRGSFGEVHRMEDKQTGFQCAVKKVRLEVFRAEELMACAGLTSPRIVPLYG-------AVREGPWVNIFMELLEGGSLGQLVKEQGC-LPEDRALYYLGQALEGLEYLHSRRILHGDVKADNVLLSSDGSHAALCDFGHAVCLQPDGLGKSLLTGDYIPGTETHMAP-EVVLGRSCDAKVDVWSSCCMMLH----------------------------MLNGCHPWTQFFRGPLCLKIASEPPPVREIPPSCAPLTAQAIQEG---------------------------LRKEPIHRVSAAELGGKVN-----------------------------RALQQVGGLKSPWRG----EYKEPRHPPPNQANYHQTLHAQPRELSPRA---PGPRPAEETTGRAPKLQPPLPPEPPEPNKSPPLTLSKEESGMWEPLPLSSLEPAPARN--------PSSPERKATVPEQELQQ---------LEIELFLNSLSQPFSLEEQEQILSCLSIDSLSLSDDSEKNPS-KASQSSRDTLSSGVHSWSSQAEARSSSWNMVLARGRPTDTPSYFNGVKVQIQSLNGEHLHIREFHRVKVGDIATGISSQIPAAAFSLVTKDGQPVRYDMEVPDSGIDLQCTLAPDG---------SFAWSWRVKHGQLENRP-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "E7FEY1-1", "uniprot_id": "E7FEY1_DANRE", "id": "E7FEY1-1", "name": "Mitogen-activated protein kinase kinase kinase 14", "aln": "-MQVQRIWNSTVPFSHMAHSDIKAVNRLGSGPDSSTESEGGELEKIVHN-------SALWKIINHGTAKYEWTHGTEKQS----IIAQAECESQ----------------------DSQEFCPN---GSISSQLVLSSISRNRPR------------------------KKRKRPRRKQGKNVSQANVSVG--VTRVPEQDSGEG---------------------------------------------------------SSINQVREPVFFSSNSSSTYSTERVSIQETEGPSDSHQWESQQTSFFSP---------------------------------SQSYAEESEELKSQLRSEIECSLAVTALRDYVTTEEPCFAYGFVKDVLRQKREKDEDEREDSDKNEGILFKEGLQPVNSEYREGREYEQCR-FLKQGSFGEVYSIKDKGTGFICAAKKVPLENFSTEEVGTWSALQSPQVVELFG-------VVREGPSIVLFMDLKPS-SLGQLVEERGR-LPEDLSLHYLQQVLGALHYLHRKRVLHLDIKADNVLLSEDGKDAFLCDFGQSERLDKQGLSYCQG----LKGTETHMAP-EVVLNEYHSSKVDIWSSCCMFLH----------------------------MLNGCHPWTRYYSRPLCLKIATEPPPLREIPHDCSSHTAEVIKAG---------------------------LQKDPIKRASAKELSFKTA-----------------------------KALKKVGGLRSQVRGG---AYQKPLGKPDSAHSATPTKSNNAMPSHN----------SELQWMSSEQKRNKADGKRNDKTKQKKQTKDTRNDDHSPPKALLHIQHTSPKPQ------VSKKTEREPTVPEQELRK---------LEKDFLLSSLSHLPSAELQEQLLSCISSDCLSTRECCDKKDSGRWSVSPGDYDSSGVFSDNSQYDGQTFSRDWLSPTHQP--LSRCFEGVDVYIRDFNGRCIHIRETPRVKVGHIARGISDQISESVFSLQTEDGFLVPHDKEVLENSLLLLCVPAPDVSLCHQYSSDDSGWSWRIREGLLETRDN------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q01389-1", "uniprot_id": "BCK1_YEAST", "id": "Q01389-1", "name": "Serine/threonine-protein kinase BCK1/SLK1/SSP31", "aln": "MPFLRKIAGTAHTHSRSDSNSSVKFGHQPTSSVASTKSSSKSPRATSRKSIYDDIRSQFPNLTPNSTSSQFYESTPVIEQSFNWTTDDHISAGTLENPTSFTNSSYKNDNGPSSLSDSRKSSGGNSVNSLSFDKLILSWDPTDPDEWTMHRVTSWFKFHDFPESWILFFKKHQLFGHRFIKLLAYDNFAVYEKYLPQTKTASYTRFQQLLKKTMTKNVTNSHIRQKSASKLKSSRSSSESIKSKLKNSKSQEDISNSRSTSESALSPTKSGPSKTDEKNFLHSTSTHQKTKSASSLYRRSFISLRGSSSSNASSAKSPSNIKLSIPARPHSIIESNSTLTKSASPPASPSYPSIFRRHHKSSSSESSLLNSLFGSGIGEEAPTKPNPQGHSLSSE-NLAKGKSKHYETNVSSPLKQSSLPTSDDKGNLWNKFKRKSQIGVPSPNTVAYVTSQETPSLKSNSSTATLTVQTADVNIPSPSSSPPPIPKTANRSLEVISTEDTPKISSTTASFKETYPDCINPDKTVPVPVNNQKYSVKNFLLDQKFYPLKKTGLNDSENKYILVTKDNVSFVPLNLKSVAKLSSFKESALTKLGINHKNVTFHMTDFDCDIGAAIPDDTLEFLKKSLFLNTSGKIYIKDQMKLQQKPKPAPLTSENNVPLKSVKSKSSMRSGTSSLIASTDDVSIVTSSSDITSFDEHASGSGRRYPQTPSYYYDRVSNTNPTEELNYWNIKEVLSHEENAPKMVFKTSPKLELNLPDKGSKLNIPTPITENESKSSFQVLRKDEGTEIDFNHRRESPYTKPELAPKREAPKPPANTSPQRTLSTSKQNKPIRLVRASTKISRSKRSKPLPPQLLSSPIEASSSSPDSLTSSYTPASTHVLIPQPYKGANDVMRRLKTDQDSTSTSPSLKMKQKVNRSNSTVSTSNSIFYSPSPLLKRGNSKRVVSSTSAADIFEENDITFADAPPMFDSDDSDDDSSSSDDIIWSKKKTAPETNNENKKDEKSDNSSTHSDEIFYDSQTQDKMERKMTFRPSPEVVYQNLEKFFPRANLDKPITEGIASPTSPKSLDSLLSPKNVASSRTEPSTPSRPVPPDSSYEFIQDGLNGKNKPLNQAKTPKRTKTIRTIAHEASLARKNSVKLKRQNTKMWGTRMVEVTENHMVSINKAKNSKGEYKEFAWMKGEMIGKGSFGAVYLCLNVTTGEMMAVKQVEVPKYSSQNEAILSTVEALRSEVSTLKDLDHLNIVQYLGFENKNNIYSLFLEYVAGGSVGSLIRMYGRFDEPLIKHLTTQVLKGLAYLHSKGILHRDMKADNLLLDQDGICKISDFGISRKSKDIYSNSDMTMRGTVFWMAPEMVDTKQGYSAKVDIWSLGCIVLEMFAGKRPWSNLEVVAAMFKIGKSKSAPPIPEDTLPLISQIGRNFLDACFEINPEKRPTANELLSHPFSEVNETFNFKSTRLAKFIKSNDKLNSSKLRITSQENKTE", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : .: . . * .. : : . ...:* . . :. . : .: :.*:. . . : . . :* . . : . . . . * :: :: * :: ..:: .: * ..:. . . .* . . : . . . . . : .. . : :* . : . . . : * . :.: *.. : : . : : * . * : .: * : ... . . :: : ** : . ..: * : . : : :* : : : : * .: :: * : . :*::.*. :: *. . .. **: : :. .. : . .::*: *:. :. : . .* ::: .: . . :. .. * ::: :. .* :: *. :.*:: * . . * :* * : : : . . . * . : . : . : .* *. :::: : :: * * . .::::*. * : : : * . .*. . . :: . .. .: . . :. : * . : .:.. :. : :. :* . : :. : . :. ::.. .. *: : ", "identical_positions": 48, "similar_positions": 255, "identity": "3.25%" }, { "cls_id": "homologset.agr.MGI:1858208", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q62651-1", "uniprot_id": "ECH1_RAT", "id": "Q62651-1", "name": "Delta(3,5)-Delta(2,4)-dienoyl-CoA isomerase, mitochondrial", "aln": "MATAMTVSSKLLGLLMQQLRGTRQLYFNVSLRSLSSSAQEASK-RIPEEVSDHNYESIQVTSAQKHVLHVQLNRPEKRNAMNRAFWRELVECFQKISKDSDCRAVVVSGAGKMFTSGIDLMDMASD-ILQPPGDDVARIAWYLRDLISRYQKTFTVIEKCPKPVIAAIHGGCIGGGVDLISACDIRYCTQDAFFQVKEVDVGLAADVGTLQRLPKVIGNRSLVNELTFTARKMMADEALDSGLVSRVFPDKDVMLNAAFALAADISSKSPVAVQGSKINLIYSRDHSVDESLDYMATWNMSMLQTQDIIKSVQAAMEKKDSKSITFSKL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O35459-1", "uniprot_id": "ECH1_MOUSE", "id": "O35459-1", "name": "Delta(3,5)-Delta(2,4)-dienoyl-CoA isomerase, mitochondrial", "aln": "MATAMTVSSKLRGLLMQQLRGTSQLYFNISLRSLSSSAQEASK-RAPEEVSDHNYESIQVTSAQKHVLHVQLNRPEKRNAMNRAFWRELVECFQKISKDSDCRAVVVSGAGKMFTSGIDLMDMASE-LMQPSGDDAARIAWYLRDLISKYQKTFTVIEKCPKPVIAAIHGGCIGGGVDLVSACDIRYCTQDAFFQIKEVDMGLAADVGTLQRLPKVIGNQSLVNELTFSARKMMADEALDSGLVSRVFQDKDAMLNAAFALAADISSKSPVAVQGSKINLIYSRDHSVDESLDYMATWNMSMLQTQDIIKSVQAAMEKRDTKSITFSKL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q13011-1", "uniprot_id": "ECH1_HUMAN", "id": "Q13011-1", "name": "Delta(3,5)-Delta(2,4)-dienoyl-CoA isomerase, mitochondrial", "aln": "MAAGIVASRRLRDLLTRRLTGSNYPGLSISLRLTGSSAQEEASGVALGEAPDHSYESLRVTSAQKHVLHVQLNRPNKRNAMNKVFWREMVECFNKISRDADCRAVVISGAGKMFTAGIDLMDMASD-ILQPKGDDVARISWYLRDIITRYQETFNVIERCPKPVIAAVHGGCIGGGVDLVTACDIRYCAQDAFFQVKEVDVGLAADVGTLQRLPKVIGNQSLVNELAFTARKMMADEALGSGLVSRVFPDKEVMLDAALALAAEISSKSPVAVQSTKVNLLYSRDHSVAESLNYVASWNMSMLQTQDLVKSVQATTENKELKTVTFSKL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9W5W8-1", "uniprot_id": "Q9W5W8_DROME", "id": "Q9W5W8-1", "name": "Delta(3,5)-Delta(2,4)-dienoyl-CoA isomerase, mitochondrial", "aln": "----MSLS-RLNTLMKLTPKPT----------AIGSLKMQRNLSALPESGPTGSFKTLAVSSPKPFVFHVELHRPSKFNAISKQMWLEIKECFDGLATNPDCRAIVLSASGKHFTAGIDLNDMINVGQTLAETDDYARKGVSMERMIKVYQDSISSLEHCPKPVITAVHKACIGAGVDLITAADIRYCTEDAFFQVKEVDIGMAADVGTLQRLPKAVGSQSLARELCFTGRKFEAAEAHSSGLVSRLFPDKDSLLTGALAVAELIASKSPVAVKTTKESLVYSLEHTNQEGLDHILLLNKLNLLSEDFAQAVAAQLTKDDKP--VFAKL", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : * :* *: : .* : . . .:::: *:*.: .*:**:*:**.* **:.: :* *: ***: :: :.****:*:*.:** **:**** ** . . ** ** . :. :*. **.::. :*:******:*:* .***.****::*.*****::*****:****:*:************.:*.:**..** *:.**: * ** .******:* **: :* .*:*:* *:*******: :* .*:** :*: *.*::: * * ::*: ::* * : : .*:**", "identical_positions": 134, "similar_positions": 97, "identity": "40.73%" }, { "cls_id": "homologset.agr.MGI:1858209", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P97738-1", "uniprot_id": "NPTX2_RAT", "id": "P97738-1", "name": "Neuronal pentraxin-2", "aln": "---MLALLTAGVALAVAAGQ--AQDNPIPGSRFVCTALPPEAARAGCPLPAMPMQGGALSPEEELRAAVLHWRETVVQQKETLGAQREAIRELTSKLARCEGLAGG-KARGTGATGKDTMGDLPRDPGH--------------------------------------VVEQLSRSLQTLKDRLESLELQ-LHTNASNAGLP--------------------------------SDFREVLQRR------LGELERQLLRKVAELEDEKSLLHNET------------------SAHRQKTENTLNALLQRVTELERGNSAFKSPDAFKVSLPLRTNYLYGKIKKTLPELYAFTICLWLRSSASPGIGTPFSYAVPGQANEIVLIEWGNNPIELLINDKVAQLP----LFVSDGKWHHICITWTTRDGMWEAFQDGEKLGTGENLAPWHPIKPGGVLILGQE--------QDTVGG------RFDATQAFVGELSQFNIWDRVLRAQEIINIAN--CSTNMPGNIIPWVDNNVDVFGGASKWPVETCEERLLDL------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O70340-1", "uniprot_id": "NPTX2_MOUSE", "id": "O70340-1", "name": "Neuronal pentraxin-2", "aln": "---MLALLTVGVALAVAAGR--AQDSPIPGSRFVCTALPPEAARAGCPLPAMPMQGGALSPEEELRAAVLQLRETVVQQKETLGAQREAIRELTGKLARCEGLAGG-KARGT---GKDTMGDLPRDPGH--------------------------------------VVEQLSRSLQTLKDRLESLELQ-LRTNVSNAGLP--------------------------------SDFREVLQRR------LGELERQLLRKVAELEDEKSLLHNET------------------SAHRQKTESTLNALLQRVTELERGNSAFKSPDAFKVSLPLRTNYLYGKIKKTLPELYAFTICLWLRSSASPGIGTPFSYAVPGQANEIVLIEWGNNPIELLINDKVAQLP----LFVSDGKWHHICITWTTRDGMWEAFQDGEKLGTGENLAPWHPIKPGGVLILGQE--------QDTVGG------RFDATQAFVGELSQFNIWDRVLRAQEIINIAN--CSTNMPGNIIPWVDNNVDVFGGASKWPVETCEERLLDL------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P47972-1", "uniprot_id": "NPTX2_HUMAN", "id": "P47972-1", "name": "Neuronal pentraxin-2", "aln": "---MLALLAASVALAVAAG---AQDSPAPGSRFVCTALPPEAVHAGCPLPAMPMQGGAQSPEEELRAAVLQLRETVVQQKETLGAQREAIRELTGKLARCEGLAGG-KARGAGATGKDTMGDLPRDPGH--------------------------------------VVEQLSRSLQTLKDRLESLEHQ-LRANVSNAGLP--------------------------------GDFREVLQQR------LGELERQLLRKVAELEDEKSLLHNET------------------SAHRQKTESTLNALLQRVTELERGNSAFKSPDAFKVSLPLRTNYLYGKIKKTLPELYAFTICLWLRSSASPGIGTPFSYAVPGQANEIVLIEWGNNPIELLINDKVAQLP----LFVSDGKWHHICVTWTTRDGMWEAFQDGEKLGTGENLAPWHPIKPGGVLILGQE--------QDTVGG------RFDATQAFVGELSQFNIWDRVLRAQEIVNIAN--CSTNMPGNIIPWVDNNVDVFGGASKWPVETCEERLLDL------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M2BBR8-1", "uniprot_id": "A0A8M2BBR8_DANRE", "id": "A0A8M2BBR8-1", "name": "", "aln": "---MRALFVALLLVYASGSGKVAGANGAKGNRFVCTAVPAGTDLS-CPVETTNRVQSTSPQEEELRNTIIQLRETILQQKETIVSQQGTIKELNSKLARCEADVRSRGSARRKDYSKNTMGDLPRDPTE--------------------------------------SVEQLGKTMQSLKDRLESLEQQ-LRTNTSNGAFP--------------------------------SELRDLLKRR------LSDLEGQLLTRVAELEEEKSQLYNET------------------AAHRQRTENTLNSLLERITELEKSNSAFKSPEDFKVALPLRTNYLYGRIKKSLPEMYAFTVCMWLKSSASPGIGTPFSYGVPGQANEIVLIEWGNSPMELLVNDKVAQLP----LSVSDGRWHHICITWTTRDGFWEAYQDGERLGTGENLAPWHPIKPGGVIILGQE--------QDIVGG------RFDATQAFVGELSHFNMWDRVLRPIDISAMAN--CSAYMPGNVVPWVDANVEVFGGATKAALEICEERLFDS------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0AB32U432-1", "uniprot_id": "A0AB32U432_DANRE", "id": "A0AB32U432-1", "name": "", "aln": "---MLHLIAGLICVYGLTCVKVVYGQTEKGERFLCTAVPIDQDTS-CPVP----VPSASLQEEELRNTVMQLRETILQQKETIVNQLGTIKELTSKLSRCESE-----SEIFRKMNKDTMDDVPKDPND--------------------------------------TIDVLGKTMQGLKDRLENLEQQQMRANASGASFP--------------------------------NELRNLLQHR------LEDLENQLLKKVNELEEEKSQLYNET------------------VAHRQRTDNTLNSLMNRISELEKGGAGFKSPENFKISLPLRTNYLFGQVKKSLPEMYAFTICMWLKSGSSPGIGTPFSYGVPGQANEIVLIEWGHNPIELLINDKVAQLP----LSLSDGRWHHVCITWTTRDGLWEAYQDGQRLGSGENLAPWHPIKPGGVLILGQEQACRLWPQQDVVGG------RFDATQAFVGELSHFNIWDRVLRSTDIITMAN--CSSYMPGNVVSWTDSNIEVFGGASKGPLELCEDRLFDN------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9V3N9-1", "uniprot_id": "Q9V3N9_DROME", "id": "Q9V3N9-1", "name": "", "aln": "MAQRLHLALVGVVLLNATASFAWKPIVGGGSGISGGTAAYSLKQSHPGAASSSHEISTSFSQFGGDKETTEVEDELLLGRAAIVNGVDSSAAVSHPISFADHLEDQYESYSIEDEAPKEPLAFPRSPVYGSDRCSVKKFAFNQDGEVEYGNPMPELDQFTICFWMRFTNHSGDHVLLTYEAGKEPREVQIWVANAQNSSFLSMAIKGQQMYRLNYPLKMRQWHHMCSSWNGKTGEWQAWLKAERIGRGFHNSLVGHKIPANGKLRSGGSSVTGEVSHGLHFEMTLVQVYRVALSAGKAHRDHKHHHVHHFDHEGQEVSSTTRAPPSINRPQPMHTLLASGQIPTRVRINLANPPPTASGAPAPGAAGAPTDSAQQAITINTNFVNGQINAGSRLVAQQLLGLSPPSGLQPSGGGKRFQMLSNSANVQFIDETETHIQFKR--NTDATKKVQKRGLVLLDDGS-----VVDDGVGSGTDGSLIYNGLADFGGQQFKQDLTLKMSLEEEISTHDREPAEEEVRAVMAICSSCHTEPFQGAIVFSWKDVREHMNNALKGLSVGPCGNF", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * : : *. : : . : .: : . .: :: : :: : :. :: .: : . .*:.* . .: : : * * * :*.....: .: : *: . .* : : :*.. * : .*. * : : : . : : . * :. .: ::* :: . *::* *:: . : * . : :. . *:* . . . : : ::: .. . *: ::: *. * *.* :. :: ::. : : : :: * . : :: *:::*.: :* **. ::. * *: : :: :: :* . .. : . : . : : * ** . : .::: : ", "identical_positions": 39, "similar_positions": 150, "identity": "6.9%" }, { "cls_id": "homologset.agr.MGI:1858210", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O70439-1", "uniprot_id": "STX7_MOUSE", "id": "O70439-1", "name": "Syntaxin-7", "aln": "MSYTPGIGGDS---------------AQLAQRISSNIQKITQCSVEIQRTLNQLGTPQDSPELRQLLQQ----------KQQYTNQLAKETDKYIKEFGSLPTTPSEQRQRKIQKDRLVAEFTTSLTNFQKAQRQAAEREKEFVARVRASSRVSGGFPE----DSSKEKNLVSWESQTQPQVQVQDEEITEDDLR----LIHERESSIRQLEADIMDINEIFKDLGMMIHEQGDMIDSIEANVESAEVHVQQANQQLSRAADYQRKSRKTLCIIIFILVVRIVIICLIVWGLKG", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O70257-1", "uniprot_id": "STX7_RAT", "id": "O70257-1", "name": "Syntaxin-7", "aln": "MSYTPGIGGDP---------------AQLAQRISSNIQKITQCSAEIQRTLNQLGTPQDTPELRQQLQQ----------EQQYTNQLAKETDKYIKEFGFLPTTPSEQRQRKIQKDRLVAEFTTALTNFQKVQRQAAEREKEFVARVRASSRVSGGFPE----DSSKEKNFVSWESQTQPQVQVQDEEITEDDLR----LIHERESSIRQLEADIMDINEIFKDLGMMIHEQGDVIDSIEANVESAEVHVQQANQQLSRAANYQRKSRKTLCIIILILVVGIVIIFFIVWGLKG", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O15400-1", "uniprot_id": "STX7_HUMAN", "id": "O15400-1", "name": "Syntaxin-7", "aln": "MSYTPGVGGDP---------------AQLAQRISSNIQKITQCSVEIQRTLNQLGTPQDSPELRQQLQQ----------KQQYTNQLAKETDKYIKEFGSLPTTPSEQRQRKIQKDRLVAEFTTSLTNFQKVQRQAAEREKEFVARVRASSRVSGSFPE----DSSKERNLVSWESQTQPQVQVQDEEITEDDLR----LIHERESSIRQLEADIMDINEIFKDLGMMIHEQGDVIDSIEANVENAEVHVQQANQQLSRAADYQRKSRKTLCIIILILVIGVAIISLIIWGLNH", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P32854-1", "uniprot_id": "PEP12_YEAST", "id": "P32854-1", "name": "Syntaxin PEP12", "aln": "MSEDEFFGGDNEAVWNGSRFSDSPEFQTLKEEVAAELFEINGQISTLQQFTATLKSFIDRGDVSAKVVERINK--RSVAKIEEIGGLIKKVNTSVKKMDAIEEASLDKTQ-IIAREKLVRDVSYSFQEFQGIQRQFTQVMKQVNERAKESLEASEMANDAALLDEEQRQNSSKSTRIPGSQIVIERDPINNEEFAYQQNLIEQRDQEISNIERGITELNEVFKDLGSVVQQQGVLVDNIEANIYTTSDNTQLASDELRKAMRYQKRTSRWRVYLLIVLLVMLLFIFLIMKL---", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "Q12241-1", "uniprot_id": "VAM3_YEAST", "id": "Q12241-1", "name": "Syntaxin VAM3", "aln": "MSFFDIEAQSSKG---NSQQEPQFSTNQKTKELSNLIETFAEQSRVLEKECTKIGSKRDSKELRYKIETELIPNCTSVRDKIESNILIHQNGKLSADFKNLKTKYQSLQQSYNQR-KSLFPLKTPISPGTSKERKDIHPRTEAVRQDPESSYISIKVNE----QSPLLHNEGQHQLQLQEEQEQQQQGLSQEELDFQTIIHQERSQQIGRIHTAVQEVNAIFHQLGSLVKEQGEQVTTIDENISHLHDNMQNANKQLTRADQHQRDRNKCGKVTLIIIIVVCMVVLLAVLS---", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "** . . :.:: : : ::: : : * :: : . . * :: .. .: : . * : : : .. .: :*: . .: : * * : :. :* . : : : :.:::: : .:*...* .:. : ::* :*::** ::::** : .*: *: : * *..:* :* :*: : :::::: .: : : ", "identical_positions": 24, "similar_positions": 94, "identity": "8.16%" }, { "cls_id": "homologset.agr.MGI:1858211", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O35986-1", "uniprot_id": "ZRAB2_RAT", "id": "O35986-1", "name": "Zinc finger Ran-binding domain-containing protein 2", "aln": "MSTKNFRVSD-----------GDWICPDKKCGNVNFARRTSCNRCGREK------------------------TTEAKMMKAGGTEIGKTLAEKSRGLFSANDWQCKTCSNVNWARRSECNMCNTPKYAKLEERTGYGGGFNERENVEYIEREESDGEYDEFGRKKKKYRGKAVGPAS---ILKEVEDKESEGEEEDEDEDLSKYKLDEDE--------DEDDADLSKYNLDASEEEDSNKKKSNRRSRSKSRSSHSRSSSRSSSPSSSRSRSRSRSRSSSSSQSRSHSGSREHSRSRGSKSRSSSRSHRGSSSPRKRSYSSSSSSPERDRKRSRSRPSSPAVRKKRRTRSRSPERH-------HRSSSGSTHSGSRSSSKKK", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9R020-1", "uniprot_id": "ZRAB2_MOUSE", "id": "Q9R020-1", "name": "Zinc finger Ran-binding domain-containing protein 2", "aln": "MSTKNFRVSD-----------GDWICPDKKCGNVNFARRTSCNRCGREK------------------------TTEAKMMKAGGTEIGKTLAEKSRGLFSANDWQCKTCSNVNWARRSECNMCNTPKYAKLEERTGYGGGFNERENVEYIEREESDGEYDEFGRKKKKYRGKAVGPAS---ILKEVEDKESEGEEEDEDEDLSKYKLDEDE--------DEDDADLSKYNLDASEEEDSNKKKSNRRSRSKSRSSHSRSSSRSSSPSSSRSRSRSRSRSSSSSQSRSHSGSREHSRSRGSKSRSSSRSHRGSSSPRKRSYSSSSSSPERDRKRSRSRPSSPAVRKKRRTRSRSPERH-------HRSSSGSTHSGSRSSSKKK", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O95218-1", "uniprot_id": "ZRAB2_HUMAN", "id": "O95218-1", "name": "Zinc finger Ran-binding domain-containing protein 2", "aln": "MSTKNFRVSD-----------GDWICPDKKCGNVNFARRTSCNRCGREK------------------------TTEAKMMKAGGTEIGKTLAEKSRGLFSANDWQCKTCSNVNWARRSECNMCNTPKYAKLEERTGYGGGFNERENVEYIEREESDGEYDEFGRKKKKYRGKAVGPAS---ILKEVEDKESEGEEEDEDEDLSKYKLDEDE--------DEDDADLSKYNLDASEEEDSNKKKSNRRSRSKSRSSHSRSSSRSSSPSSSRSRSRSRSRSSSSSQSRSRSSSRERSRSRGSKSRSSSRSHRGSSSPRKRSYSSSSSSPERNRKRSRSRSSSSGDRKKRRTRSRSPERR-------HRSSSGSSHSGSRSSSKKK", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M6Z7B1-1", "uniprot_id": "A0A8M6Z7B1_DANRE", "id": "A0A8M6Z7B1-1", "name": "Zinc finger Ran-binding domain-containing protein 2", "aln": "MSGKSFRVSD-----------GDWICPDKKCGNVNFARRTSCNRCGREK------------------------TTEAKMMKAGGTEIGKTLAEKSRGLFSANDWQCKTCGNVNWARRSECNMCNTPKYAKLEERTGYGGGFNERENLVYNEREESDGEYDEFGRIKKKFRGKTKKDSDKKEEPKKVDQDDEEEDDDDEDGDLSKYKLDDDDEDDDDDDDDEDDADLSKYDLDDGDE-----KKG-------SHSGSSRSSSRSSS-SSSRSRSRSRSRSSSSSRSRS--------RSR-SKSRSSSRSGKGSASSKKRSRSPSSS-PEGGQKRSRSRSSSGG-RKKRRARSHSSERFGVTHGVLDTRRPSALYTGLSDKTVHD", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9W230-1", "uniprot_id": "Q9W230_DROME", "id": "Q9W230-1", "name": "Zinc finger Ran-binding domain-containing protein 2", "aln": "MSSSNGGVASGAAGSSGVASPGDWICPDYDCRHLNFARRLQCNKCDRDRDGSDKPERDRDRDRERERGNGSSSSSSSSSKKKLGTEIGKAAADKSRGLFSAEDWQCSKCANVNWARRQTCNMCNAPKFSDVEERTGFGGGYNDRGVVEYKDRQDSDSEYDEFGRRKKRKHGEHREDSK----RPRRSSRDEQRNDEEEDE-------DDDE---------GDDEDLSKYDLWGDEE-----------------VTSTDVKSKEGTGNGDKERKRT-SRDSTSSVSSS--------------SSSSSSSSSDSSS------SSSSSSSSGGRRK----TSSSGRR---------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "** .. *:. ******* .* ::***** .**:*.*:: ::.:. * ******: *:********:****..*.*******. *****:**::.:*****:***:*:* : * :*::**.******* **: :*: :. . .. :.: ::::** *:*: ** *****:* .:* : .*:..: ...:.*.*: **.*:** * * * *** * .*:* *.*** .. .::: .** . * ", "identical_positions": 116, "similar_positions": 83, "identity": "30.29%" }, { "cls_id": "homologset.agr.MGI:1858213", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "M0RAD5-1", "uniprot_id": "M0RAD5_RAT", "id": "M0RAD5-1", "name": "ATP-dependent Clp protease proteolytic subunit", "aln": "MGQRRGFSLFIRTPINEDPTHRLTPPSSAPPISFSEVDEPAAPAKHAGCCSSGNQAWMHGGMWPRVLLRDGRAAAGGCRALLSRFAVRFS----PPWSTGSDSPLRSNLHGTATRAFPLIPIVVEQTGRGERAYDIYSRLLRERIVCVMGPIDDSVASLVIAQLLFLQSESNKKPIHMYINSPGGVVTAGLAIYDTMQYILNPICTWCVGQAASMGSLLLAAGSPGMRHSLPNSRIMIHQPSGGARGQATDIAIQAEEIMKLKRQLYNIYAKHTKQSLQVIESAMERDRYMSPMEAQEFGILDKVLVHPPQDGEDEPELVQKE-TTTAPADPPAPAGT-----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O88696-1", "uniprot_id": "CLPP_MOUSE", "id": "O88696-1", "name": "ATP-dependent Clp protease proteolytic subunit, mitochondrial", "aln": "-------------------------------------------------------------MWPRVLLGEARVAVDGCRALLSRLAVHFS----PPWTAVSCSPLRRSLHGTATRAFPLIPIVVEQTGRGERAYDIYSRLLRERIVCVMGPIDDSVASLVIAQLLFLQSESNKKPIHMYINSPGGVVTAGLAIYDTMQYILNPICTWCVGQAASMGSLLLAAGSPGMRHSLPNSRIMIHQPSGGARGQATDIAIQAEEIMKLKKQLYNIYAKHTKQSLQVIESAMERDRYMSPMEAQEFGILDKVLVHPPQDGEDEPELVQKE-TATAPTDPPAPTST-----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q16740-1", "uniprot_id": "CLPP_HUMAN", "id": "Q16740-1", "name": "ATP-dependent Clp protease proteolytic subunit, mitochondrial", "aln": "-------------------------------------------------------------MWPGILVGGARVASCRYPALGPRLAAHFPAQRPPQRTLQNGLALQRCLHATATRALPLIPIVVEQTGRGERAYDIYSRLLRERIVCVMGPIDDSVASLVIAQLLFLQSESNKKPIHMYINSPGGVVTAGLAIYDTMQYILNPICTWCVGQAASMGSLLLAAGTPGMRHSLPNSRIMIHQPSGGARGQATDIAIQAEEIMKLKKQLYNIYAKHTKQSLQVIESAMERDRYMSPMEAQEFGILDKVLVHPPQDGEDEPTLVQKEPVEAAPAAEPVPAST-----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VKY3-1", "uniprot_id": "Q9VKY3_DROME", "id": "Q9VKY3-1", "name": "ATP-dependent Clp protease proteolytic subunit", "aln": "---------------------------------------------------------------------MLKTAVSRFLQISS---------------------VQCGGRANSVRNINLIPMVVEQTGRGERAYDIFSRLLKERIICLMGNITDDISSTVVAQLLFLQSENVNKPIHLYINSPGGVVTAGLAIYDTMQYVKPPIATWCVGQACSMGSLLLAAGAPGMRYSLPNARIMIHQPSGGAQGQATDILIHAEEIIKIKRQLTNIYVKHAKNTYEEMSGRMERDHFMTPEEAKVLGIIDHVLEHPPETVSETGPASDGGVTSGKAVPEECEKKRSKQAA", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :.* : . :: :..:.* : ***:**************:****:***:*:** * *.::* *:*********. :****:*********************: **.*******.**********:****:****:***********:****** *:****:*:*:** ***.**:*:: : :.. ****::*:* **: :**:*:** ***: .: : . .. ", "identical_positions": 142, "similar_positions": 57, "identity": "41.4%" }, { "cls_id": "homologset.agr.MGI:1858214", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9QZ67-1", "uniprot_id": "PPM1D_MOUSE", "id": "Q9QZ67-1", "name": "Protein phosphatase 1D", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------MAGLYSLGVSVFSDQGG----------RKYMEDVTQIVVEPEPAAEDKPAPVPRRALGLPATPT---LAGVGPSEKGPAAAR----DPAPDAAASLP--------------AGRCCR--------------------RRSSVAFFAVCDGHGGREAAQFAREHLWGFIKKQKGFTSSEPAKVCAAIRKGFLACHLAMWKKLAEWPKTMTGLPSTSGTTASVVIIRGMKMYVAHVGDSGVVLGIQDDPKDDFVRAVEVTQDHKPELPKERERIEGLGGSVMNKSGVNRVVWKRPR-LTHSGPVRRSTVIDQIPFLAVARALGDLWSYDFFSGKFVVSPEPDTSVHTLDPRKHKYIILGSDGLWNMVPPQDAISMCQDQEEKKYLMGEQ-GQSCAKMLVNRALGRWRQRMLRADNTSAIVICISPEVDNQGNFT----------------------------------------------------------------------------------------------NEDELFLNLTDSPTYNSQETCVMTSSPSSTPPIKSPEEDAWPRLSSKDHIPALVRSNAFSEKFLEVPAEIARGNIQTVVMTS--------------------------------------------------------------------------------------------KDSETLEENCPK------------------------------------------------------------------------------ALTLRIHDSLNNTLSVGLIPTNSTNTIMDQKNLKMSTPGQMKAQEVERTPPANFKRTLEE--------------------------------------------------------------SNSGPLMKKHR-----------------------------------------------------------------RNGLSRSSGAQASSLPTASQR-----------------RHSVKLTLRRRLRGQRKMGNPLLHQHRKTVCVC------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "B1WCA0-1", "uniprot_id": "B1WCA0_RAT", "id": "B1WCA0-1", "name": "", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------MAGLYSLGVSVFSDQGG----------RKYMEDVTQIVVEPEPAAEDKPAPVPRRALGLPATPS---LVGVGPSGKGPAAAR----DPAPDAAASLP--------------AGRCCR--------------------RRSSVAFFAVCDGHGGREAAQFAREHLWGFIKKQKGFTSSEPAKVCAAIRKGFLACHLAMWKKLAEWPKTMTGLPSTSGTTASVVIIRGMKMYVAHVGDSGVVLGIQDDPKDDFVRAVEVTQDHKPELPKERERIEGLGGSVMNKSGVNRVVWKRPR-LTHSGPVRRSTVIDQIPFLAVARALGDLWSYDFFSGKFVVSPEPDTSVHTLDPQKHKYIILGSDGLWNMVPPQDAISMCQDQEEKKYLMGEQ-GQSCAKMLVNRALGRWRQRMLRADNTSAIVICISPEVDNQGNFT----------------------------------------------------------------------------------------------NEDELFLNLTDSPTYNSQETCVMTPSPSSTPPVKSLEEDPWPRLNSKDHIPALVRSNAFSEKFLEVPAEIARGSIQTVVMTS--------------------------------------------------------------------------------------------KDSETLEENCPK------------------------------------------------------------------------------ALTLRIHDSLNNTLSVGLMPTNSTNTIMDQKNLKMSTPGQMKAQEVERTPPANFKRTLEE--------------------------------------------------------------SNSGPLMKKHR-----------------------------------------------------------------RNGLSRNSGAQASSLPTASQR-----------------RHSVTLTMRRRLRGQKKMGNPLLHQHRKTVCVC------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O15297-1", "uniprot_id": "PPM1D_HUMAN", "id": "O15297-1", "name": "Protein phosphatase 1D", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------MAGLYSLGVSVFSDQGG----------RKYMEDVTQIVVEPEPTAEEKPSPRRSLSQPLPPRPSPAALPGGEVSGKGPAVAAREARDPLPDAGASPA--------------PSRCCR--------------------RRSSVAFFAVCDGHGGREAAQFAREHLWGFIKKQKGFTSSEPAKVCAAIRKGFLACHLAMWKKLAEWPKTMTGLPSTSGTTASVVIIRGMKMYVAHVGDSGVVLGIQDDPKDDFVRAVEVTQDHKPELPKERERIEGLGGSVMNKSGVNRVVWKRPR-LTHNGPVRRSTVIDQIPFLAVARALGDLWSYDFFSGEFVVSPEPDTSVHTLDPQKHKYIILGSDGLWNMIPPQDAISMCQDQEEKKYLMGEH-GQSCAKMLVNRALGRWRQRMLRADNTSAIVICISPEVDNQGNFT----------------------------------------------------------------------------------------------NEDELYLNLTDSPSYNSQETCVMTPSPCSTPPVKSLEEDPWPRVNSKDHIPALVRSNAFSENFLEVSAEIARENVQGVVIPS--------------------------------------------------------------------------------------------KDPEPLEENCAK------------------------------------------------------------------------------ALTLRIHDSLNNSLPIGLVPTNSTNTVMDQKNLKMSTPGQMKAQEIERTPPTNFKRTLEE--------------------------------------------------------------SNSGPLMKKHR-----------------------------------------------------------------RNGLSRSSGAQPASLPTTSQR-----------------KNSVKLTMRRRLRGQKKIGNPLLHQHRKTVCVC------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9W4H8-1", "uniprot_id": "Q9W4H8_DROME", "id": "Q9W4H8-1", "name": "", "aln": "MLPANNRSSTSTHTNTNANTINATTNTTNRCLINTAIEKTVVRLRETAANSGTFQDSDESSVEFDIINYYGDDGGTTPAPAPATASVTRHGGSSSGNNNNNSACHPALDASSDVVVVEPAAVGVAQEEEEEPEQRPERISIPIPDLAFTEMEAYAEDIVVDMEGGSPAKPLNPKKQRLNSATTTTINRSRGGGAAQSRLRRSAAIVPPRSIPESCASSSNSNSSSSSNSNSSSSSATGSSASTGNPSPCSSLGVNMRVTGQCCQGGRKYMEDQFSVAYQESPITHELEYAFFGIYDGHGGPEAALFAKEHLMLEIVKQKQFWSDQDEDVLRAIREGYIATHFAMWREQEKWPRTANGHLSTAGTTATVAFMRREKIYIGHVGDSGIVLGYQNKGERNWR-ARPLTTDHKPESLAEKTRIQRSGGNVAIKSGVPRVVWNRPRDPMHRGPIRRRTLVDEIPFLAVARSLGDLWSYNSRFKEFVVSPDPDVKVVKINPSTFRCLIFGTDGLWNVVTAQEAVDSVRKEHLIGEILNEQDVMNPSKALVDQALKTWAAKKMRADNTSVVTVILTPAARNNSPTTPTRSPSAMARDNDLEVELLLEEDDEELPTLDVENNYPDFLIEEHEYVLDQPYSALAKRHSPPEAFRNFDYFDVDEDELDEDEETVEEDEEEEEEEEETKSVGILQQSLFNPRKTWRKSTINNSWSGVTEPEPEPDPEPDRIDVLTLDMYSHTSIDKGTNYGGSIAQSSIDPAETAENRELSELEQHLESSYSFAESYNSLLNEQEEQEARSRSAAAAAAAAEAAAVEAQQTTAHSASVVLDRSMLEIIQEQQHYQQQEGYSLTQLETRRERERLTESWPQQPAELLELDALLQQERAEEEQVALEQQQQREQQMEQMEVEAISSSGQHEFAYPVTTATASEWCATLQEDEEELDSTVIDIVIQPEQELQDNEVSSTLPATPTHVEPEQIVDKMEPLKVQEMLTAVEKPPSKQEKKLPKKQETKQVAVLDTVAEMPKEDAHAVHYIFQRIQKVQDSEATPVAVTNSTMADALPTESSGLGGSMTAPRIRRYRNVPNENHQHMQTRRRQIFKHVKPKSFIQSSAAAIVAYGDSTETVGGTAGASGTPAAGRVGGGGGGGGGRGSASGGSSPAVAANSRRSVNVVANASGNSASKVVPSSSSMMMTRRSHTLTASGGVNKRQLRSSLCTLGLGVGVGVGLGMDLDMTKRTLRTRNVPALSGGSATPSSNSSPASGGSSPAGFTSPASPVITSRGSGSRTTASPARRLKRSHEDREQRMSLRRSTLSGSASGSGLVGTGGSPSNVKSNRLQACNGAISARPPPSPKKLNAAVPTLAIGTRAYTAALAAAADHLNKRWSLRSSSGNSGNLITAISCYSDRSRAATAAGSPGSGGGAAGPPGASLAASTVGTRRR", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :: : : . .:. * * :: ::..* .:: . . : : :*. . . * ...: .. ..:.** ..:**: :. . ***.: ***** *** **:*** * *** * *.: .* ***:*::* *:***:: :**:* .* **:****:*.::* *:*:.******:*** *:. : :: * :* ***** *: **: **.* **** ****:*** * **:** *::*:********:*******: :*****:**..* .::* ..: :*:*:*****::..*:*:. :.:. ::.*: . :* **::** * : :******.:.: ::* . *:. * :*: :.: :.. :*.::* :. * . :.. * :. *. . * :. : *:: :: : ..**: .:: . .. :: * * *. .: :.:: .:.*::. . :*:..*:. :* **.. : ..**:: ::.* : * :.* ::::* .* . **....::.: *:* * .: : ** : *. :* *.::*. ", "identical_positions": 182, "similar_positions": 225, "identity": "12.75%" }, { "cls_id": "homologset.agr.MGI:1858215", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0ABK0M525-1", "uniprot_id": "A0ABK0M525_RAT", "id": "A0ABK0M525-1", "name": "RWD domain-containing protein", "aln": "MAKKATYKRLSFSLILSQSLIKLLRNFRCLSMVEMEQAEAQLSELDLLASMFPGENELIVNDQLALAELKDCIEKRTMEGRSSKVYFTINVSLDFNEAAMVMFSLSCILPFKYPTVLPEITVRSVSLSRSQQTQLNTDLTAYLQKHCLGEVCILNATEWVKEHASDYVNRDASPS-PARQSTVQPVDLTFTRLWIYSHHIYNKCKRRNILEWARELSLSGFSMPGKPGVVCVEGPQSACEEFWSRLRKLNWKRILIRHREDIPFDS--TTEKMEEQRKFSIFEEKAFNVHGARGNHMDFGQLYQFLNARGCGDVFQMFFGVEGQ", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q99M03-1", "uniprot_id": "RWD2B_MOUSE", "id": "Q99M03-1", "name": "RWD domain-containing protein 2B", "aln": "-------------------------------MVEMEQAEAQLSELDLLASMFPSENELIVNDQLALAELKDCIEKRTMEGRSSQVYFTINVSLDLSEAAVVTFSLSCILPFKYPTVLPEITVRSVSLSRSQQTQLNTDLIAYLQKNCLGDVCILNATEWVKEHAFDYVNIEALPS-PARQSTAQPEDLAFTRLWIYSHHIYNKCKRRNILEWAKELSLTGFSMPGKPGVVCVEGPQSACEEFWSRLRKLNWKRILIRHREDIPLDG--TAGGMEGQRKFPILEEKAFSVHGARGNHMDFGQLYQFLNARGCGDVFQMFFGVEGQ", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P57060-1", "uniprot_id": "RWD2B_HUMAN", "id": "P57060-1", "name": "RWD domain-containing protein 2B", "aln": "--MKIELSMQPWNPGYSSEGATAQETYTCPKMIEMEQAEAQLAELDLLASMFPGENELIVNDQLAVAELKDCIEKKTMEGRSSKVYFTINMNLDVSDEKMAMFSLACILPFKYPAVLPEITVRSVLLSRSQQTQLNTDLTAFLQKHCHGDVCILNATEWVREHASGYVSRDTSSS-PTTGSTVQSVDLIFTRLWIYSHHIYNKCKRKNILEWAKELSLSGFSMPGKPGVVCVEGPQSACEEFWSRLRKLNWKRILIRHREDIPFDG--TNDETERQRKFSIFEEKVFSVNGARGNHMDFGQLYQFLNTKGCGDVFQMFFGVEGQ", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AB32T6V4-1", "uniprot_id": "A0AB32T6V4_DANRE", "id": "A0AB32T6V4-1", "name": "", "aln": "-----------------------------MNMTCSEEADAQLAEIELLISMFPSEEELQV-DEISHAELRAYVEGSAHTPPTSRPQFSIMVKVEN---PAACITMVCSYPNDYPKELPDITVRCAELIRSQQMQLHSDLNNYLTENCRGEVCVLSAVQWIKDNACVYFTKSAAFSEPKKEHALTQPKTTFSRLWIYSHHIYNKIKRKNILEWAKELNLSGFSMPGKPGIVCVEGLQSVCDEFWARLKVLTWKRIMICHREDVPLDSSWTEERIESLRKFTLFHEAIFYPHGTKGNHMDLGQLYQFLNDKGCADIFQLYFGIKGQ", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * *:*:***:*::** ****.*:** * *::: ***: :* : :*: *:* :.:: . ::: * * .** **:****.. * **** **::** :* ::* *:**:*.*.:*::::* *.. .: * * : . *:************ **:******:**.*:*********:***** **.*:***:**: *.****:* ****:*:*. * * ***.::.* * :*::*****:******** :**.*:**::**::**", "identical_positions": 144, "similar_positions": 78, "identity": "44.44%" }, { "cls_id": "homologset.agr.MGI:1858216", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P61087-1", "uniprot_id": "UBE2K_MOUSE", "id": "P61087-1", "name": "Ubiquitin-conjugating enzyme E2 K", "aln": "---------------------------------------------------MANIAVQRIKREFKEVLK--------------------SEETSKNQIKVDLVDEN-FTELRGEIAGPPDTPYEGGRYQLEIKIPETYPFNPPKVRFITKIWHPNISSVTGAICLDILKDQWAAAMTLRTVLLSLQALLAAAEPDDPQDAVVANQYKQNPEMFKQTARLWAHVYAGAPVSSPEYTKK-----------IENLCAMGFDRNAVIVALS---------SKSWDVETATELLLSN", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P61086-1", "uniprot_id": "UBE2K_HUMAN", "id": "P61086-1", "name": "Ubiquitin-conjugating enzyme E2 K", "aln": "---------------------------------------------------MANIAVQRIKREFKEVLK--------------------SEETSKNQIKVDLVDEN-FTELRGEIAGPPDTPYEGGRYQLEIKIPETYPFNPPKVRFITKIWHPNISSVTGAICLDILKDQWAAAMTLRTVLLSLQALLAAAEPDDPQDAVVANQYKQNPEMFKQTARLWAHVYAGAPVSSPEYTKK-----------IENLCAMGFDRNAVIVALS---------SKSWDVETATELLLSN", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8I6A356-1", "uniprot_id": "A0A8I6A356_RAT", "id": "A0A8I6A356-1", "name": "Ubiquitin-conjugating enzyme E2 K", "aln": "LLFFFWFFFSELGTELRALRFLGKCSTTELNPQPRLLLLYVTGAIVTDFISLSCIPSLHYRSRAEEVAQWLQCWLLKCGELSSDLKHSCKSQTSKNQIKVDLVDEN-FTELRGEIAGPPDTPYEGGRYQLEIKIPETYPFNPPKVRFITKIWHPNISSVTGAICLDILKDQWAAAMTLRTVLLSLQALLAAAEPDDPQDAVVANQYKQNPEMFKQTARLWAHVYAGAPVSSPEYTKK-----------IENLCAMGFDRNAVIVALS---------SKSWDVETATELLLSN", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P52486-1", "uniprot_id": "UBCD4_DROME", "id": "P52486-1", "name": "Ubiquitin-conjugating enzyme E2-22 kDa", "aln": "---------------------------------------------------MANMAVSRIKREFKEVMR--------------------SEEIVQCSIKIELVNDS-WTELRGEIAGPPDTPYEGGKFVLEIKVPETYPFNPPKVRFITRIWHPNISSVTGAICLDILKDNWAAAMTLRTVLLSLQALLAAAEPDDPQDAVVAYQFKDKYDLFLLTAKHWTNAYAGGPHTFPDCDSK-----------IQRLRDMGIDEHEARAVLS---------KENWNLEKATEGLFS-", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P21734-1", "uniprot_id": "UBC1_YEAST", "id": "P21734-1", "name": "Ubiquitin-conjugating enzyme E2 1", "aln": "--------------------------------------------------------MSRAKRIMKEIQA--------------------VKDDPAAHITLEFVSESDIHHLKGTFLGPPGTPYEGGKFVVDIEVPMEYPFKPPKMQFDTKVYHPNISSVTGAICLDILKNAWSPVITLKSALISLQALLQSPEPNDPQDAEVAQHYLRDRESFNKTAALWTRLYASETSNGQKGNVEESDLYGIDHDLIDEFESQGFEKDKIVEVLRRLGVKSLDPNDNNTANRIIEELLK-", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : :*: .: *.:::*.:. .*:* : ***.******:: ::*::* ***:***::* *:::*****************: *:..:**::.*:****** :.**:***** ** :: . : * ** *:. **. . . . : *:.: *::.. .* ... : * *:. ", "identical_positions": 71, "similar_positions": 66, "identity": "24.32%" }, { "cls_id": "homologset.agr.MGI:1858219", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9JHG2-1", "uniprot_id": "RCAN2_MOUSE", "id": "Q9JHG2-1", "name": "Calcipressin-2", "aln": "-------------------------------------------------------------------------------------------MP---------APSMD---------CDVST-LVACVVDVEVFTNQEVKEKFEGLFRTYDECVTFQLFKSFRRVRINFSHPKSAARARIELHETQFRGK-KLKLYFAQVQTPETDGDKLHLAPPQPAKQFLISPPSSPPVGWKP-ISDATPVLNYDLLYAVAKLGPGEKYELHAGTEST---------PSVVVHVCDSDMEEEEDPKTSPKPKIIQTRRPGLPPSVSN---", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8CH27-1", "uniprot_id": "RCAN2_RAT", "id": "Q8CH27-1", "name": "Calcipressin-2", "aln": "-------------------------------------------------------------------------------------------MP---------APSMD---------CDVST-LVACVVDVEVFTNQEVKEKFEGLFRTYDECVTFQLFKSFRRVRINFSHPKAAARARIELHETQFRGK-KLKLYFAQVQTPETDGDKLHLAPPQPAKQFLISPPSSPPVGWKP-ISDATPVLNYDLLYAVAKLGPGEKYELHAGTEST---------PSVVVHVCDSDLEEEEDPKTSPKPKIIQTRRPGLPPSVSN---", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q14206-1", "uniprot_id": "RCAN2_HUMAN", "id": "Q14206-1", "name": "Calcipressin-2", "aln": "-------------------------------------------------------------------------------------------MP---------APSMD---------CDVST-LVACVVDVEVFTNQEVKEKFEGLFRTYDDCVTFQLFKSFRRVRINFSNPKSAARARIELHETQFRGK-KLKLYFAQVQTPETDGDKLHLAPPQPAKQFLISPPSSPPVGWQP-INDATPVLNYDLLYAVAKLGPGEKYELHAGTEST---------PSVVVHVCDSDIEEEEDPKTSPKPKIIQTRRPGLPPSVSN---", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "E7F2L5-1", "uniprot_id": "E7F2L5_DANRE", "id": "E7F2L5-1", "name": "", "aln": "-------------------------------------MKGEHLFAN---------------------MRSAPFFQRIYLLGGEELVVLQSTMG---------ESSLGDSFQQITDFNDLPTSLFACNVDQSVFEDHEGKEMFEALFLAYDEGVTFQQFKSFRRVRINFSNPKAAASARIELHETPFRGK-KLKLYFAQVQNPVSEGDNLHLAPPQPSKQFLISPPGSPPVGWQQ-IDEATPVINYDLLYAVAKLGPGEKFELHAGTEST---------PSVVVHVCDSDTDEEEEPKNNPKPKIIQTRRPDLP--VSH---", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9XZL8-1", "uniprot_id": "SRA_DROME", "id": "Q9XZL8-1", "name": "Protein sarah", "aln": "MSDAAKSNNNASADAPDPTTPDATGEADAANAATPTTPRGNHNNNNSANGRSKNKLKSTQNSSGGGSIDKLSPDQDIFINAADGLPNQHPSLPKEGDVDSDTEPEVDADS-----FDDLPTSIIVTNIHSEVFANPELKHAMEELFRTFSESATFQWLRSFRRLRVNYDNAIAAANARIKLHQYEFNKKTVITCYFAQPVTPVS---NKNLQPPAPVKQFLISPPASPPAGWEP-REEGEPLVNHDLLAALASLTPGESHELHPQSEDQ---------PAIIVHTA---MLAETGPGLQVKAPIVQTKCPERA--------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P36054-1", "uniprot_id": "RCN1_YEAST", "id": "P36054-1", "name": "Calcipressin-like protein", "aln": "-------------------------------------------------------------------------------------------MG---------NIITDT------IIITSDKCDIVDNDNVERIQVWLSKNILRKFQINENEPLQLIILKRFKRILLICPSHDISQHVMDASRALEMENF----NFSYSLQDGQRNLTKQYLKVPESEKMFLISPPASPPPEFDFSKCEDAPQRHIQSHIQQDQQQRLEASQLLPNNPDKNNNGTFTLLKSKVGAITIDRCPTNDGNGQMQLADHVKTAFPPKSIFDTDDDD", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . . .. . . : *. :. : .: : :: *:*: : : . : :. : . : * * . * ******.*** :. : * : : . * :* . . . : : : . ::* * . ", "identical_positions": 20, "similar_positions": 47, "identity": "6.23%" }, { "cls_id": "homologset.agr.MGI:1858220", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "F7ENE7-1", "uniprot_id": "F7ENE7_RAT", "id": "F7ENE7-1", "name": "", "aln": "MRARRTRPFGAPPTTRRLPPTQLSAPPSCLCAGAAHPLGARNPGRARGARVRERARRRRPHSAPGHRPCSRLRWPLGPASRAWWLPAVKVCPPLAVLVSPPGPLPWSAQDAGIVALLCFPGFWKLVVRLLLKHRAFNSCFQAAGFQLPCEISSSPLALSGQRPRTLPTEKMLRDSLKSWNDSQSDLCSSDQEEEEEMVFGENEDDLEEMMDLSDLPTSLFACSVHEAVFEVQEQKERFEALFTLYDDQVTFQLFKSFRRVRINFSKPEAAARARIELHESEFHGRKLKLYFAQVQVSGEARDKSYLLPPQPTKQFLISPPASPPVGWKQSEDATPVINYDLLCAVSKLGPGEKYELHAGTESTPSVVVHVCESETEEEEDTKNPKQKITQTRRPEAPTAALSER--LDCAL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9JKK0-1", "uniprot_id": "RCAN3_MOUSE", "id": "Q9JKK0-1", "name": "Calcipressin-3", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------MLRDSLKSWNDSQSDLCSSDQEEEEEMVFGENEDGLEEMMDLSDLPTSLFACSVHEAVFEVQEQKERFEALFTLYDDQVTFQLFKSFRRVRINFSKPEAAARARIELHESEFHGRKLKLYFAQVQVSGEARDKSYLLPPQPTKQFLISPPASPPVGWKQSEDAMPVINYDLLCAVSKLGPGEKYELHAGTESTPSVVVHVCESETEEEEDTKNPKQKITQTRRPEAPTAALSER--LDCAL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9UKA8-1", "uniprot_id": "RCAN3_HUMAN", "id": "Q9UKA8-1", "name": "Calcipressin-3", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------MLRDTMKSWNDSQSDLCSTDQEEEEEMIFGENEDDLDEMMDLSDLPTSLFACSVHEAVFEAREQKERFEALFTIYDDQVTFQLFKSFRRVRINFSKPEAAARARIELHETDFNGQKLKLYFAQVQMSGEVRDKSYLLPPQPVKQFLISPPASPPVGWKQSEDAMPVINYDLLCAVSKLGPGEKYELHAGTESTPSVVVHVCESETEEEEETKNPKQKIAQTRRPDPPTAALNEPQTFDCAL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9XZL8-1", "uniprot_id": "SRA_DROME", "id": "Q9XZL8-1", "name": "Protein sarah", "aln": "--------MSDAAKSNNNASADAPDPTTPDATGEADAANAATPTTPRGNHNNNNSANGRSKNK---------------------------------------------------------------------------------------------LKSTQNSSGGGSIDKLSPDQDIFINAADGLPNQHPSLPKEGDVDSDTEPEVDADSFDDLPTSIIVTNIHSEVFANPELKHAMEELFRTFSESATFQWLRSFRRLRVNYDNAIAAANARIKLHQYEFNKKTVITCYFAQPVTPVSNKN--LQPPAPVKQFLISPPASPPAGWEPREEGEPLVNHDLLAALASLTPGESHELHPQSEDQPAIIVHTAMLAETGPG--LQVKAPIVQTKCPERA--------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * . : :: ..* . . . :* ...: : : .:.*****::. .:*. ** * *. :* ** :.:..*** ::****:*:*:.:. ***.***:**: :*: :.: : :: ..: * ** *.************.**: *:. *::*:***.*::.* ***.:***. :*. *:::**.. : * *.**: *: . ", "identical_positions": 75, "similar_positions": 81, "identity": "18.25%" }, { "cls_id": "homologset.agr.MGI:1858222", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q80UG5-1", "uniprot_id": "SEPT9_MOUSE", "id": "Q80UG5-1", "name": "Septin-9", "aln": "--MKKSYSGVTRTSSGRLRRLA-------DPTGPALKRSFEVEEIEPPNS---TPPRRVQTPLLRATVASSSQKFQDLGVKNSEPAARLVDSLSQ--RSPKPSLRRVELAGAKAPEPMSRRTEISIDISS----KQVESTASAAGPSRFGLKRAEVLGHKTPEPVPRR------TEITIVKPQESVLRRVETPASKIPEGSAVPATDAAP-------KRVEIQVPKPAEAPNCPLPSQTLENSE-APMSQLQSRLEPRP--SVAEVPYRNQEDSEVTPSCVGD-------MADNPRDAMLKQAPASRNEKAPMEFGYVGIDSILEQMRRKAMKQGFEFNIMVVGQSGLGKSTLINTLFKS-KISRKSVQPTSEERIPKTIEIKSITHDIEEKGVRMKLTVIDTPGFGDHINNENCWQPIMKFINDQYEKYLQEEVNINRKKRIPDTRVHCCLYFIPATGHSLRPLDIEFMKRLSKVVNIVPVIAKADTLTLEERVYFKQRITADLLSNGIDVYPQKEFDEDAEDRLVNEKFREMIPFAVVGSDHEYQVNGKRILGRKTKWGTIEVENTTHCEFAYLRDLLIRTHMQNIKDITSNIHFEAYRVKRLNEGNSAMAN-------GIE-KEPEAQEM--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9QZR6-1", "uniprot_id": "SEPT9_RAT", "id": "Q9QZR6-1", "name": "Septin-9", "aln": "--MER-----DRIT--------------------ALKRSFEVEEIEPPNS---TPPRRVQTPLLRATVASSSQKFQDLGVKNSEPAARLVDTLSQ--RSPKPSLRRVDLAGAKAPEPMSRRTELSIDISS----KQVESTASTPGPSRFGLKRAEVLGHKTPEPVPRR------TEITIVKPQESGLRRVETPASKAPEGSAMPVTDAAP-------KRVEIQVPKPAEAPNCPLPPQTLENSE-APMSQLQSRLEPRP--PVTEVPYRNQEDSEVAPSCVVD-------MADNPRDAMLKQAPVSRNEKAPVDFGYVGIDSILEQMRRKAMKQGFEFNIMVVGQSGLGKSTLINTLFKS-KISRKSVQPISEERIPKTIEIKSITHDIEEKGVRMKLTVIDTPGFGDHINNENCWQPIMKFINDQYEKYLQEEVNINRKKRIPDTRVHCCLYFIPATGHSLRPLDIEFMKRLSKVVNIVPVIAKADTLTLEERVYFKQRITSDLLSNGIDVYPQKEFDE-AEDRLVNEKFREMIPFAVVGSDHEYQVNGKRILGRKTKWGTIEVENTTHCEFAYLRDLLIRTHMQNIKDITSNIHFEAYRVKRLNEGNSAMAN-------GIE-KEPETQEM--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9UHD8-1", "uniprot_id": "SEPT9_HUMAN", "id": "Q9UHD8-1", "name": "Septin-9", "aln": "--MKKSYSGGTRTSSGRLRRLG-------DSSGPALKRSFEVEEVETPNS---TPPRRVQTPLLRATVASSTQKFQDLGVKNSEPSARHVDSLSQ--RSPKASLRRVELSGPKAAEPVSRRTELSIDISS----KQVEN-AGAIGPSRFGLKRAEVLGHKTPEPAPRR------TEITIVKPQESAHRRMEPPASKVPEVPTAPATDAAP-------KRVEIQMPKPAEAPTAPSPAQTLENSEPAPVSQLQSRLEPKPQPPVAEATPRSQEATEAAPSCVGD-------MADTPRDAGLKQAPASRNEKAPVDFGYVGIDSILEQMRRKAMKQGFEFNIMVVGQSGLGKSTLINTLFKS-KISRKSVQPTSEERIPKTIEIKSITHDIEEKGVRMKLTVIDTPGFGDHINNENCWQPIMKFINDQYEKYLQEEVNINRKKRIPDTRVHCCLYFIPATGHSLRPLDIEFMKRLSKVVNIVPVIAKADTLTLEERVHFKQRITADLLSNGIDVYPQKEFDEDSEDRLVNEKFREMIPFAVVGSDHEYQVNGKRILGRKTKWGTIEVENTTHCEFAYLRDLLIRTHMQNIKDITSSIHFEAYRVKRLNEGSSAMAN-------GMEEKEPEAPEM--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AB13ABE0-1", "uniprot_id": "A0AB13ABE0_DANRE", "id": "A0AB13ABE0-1", "name": "", "aln": "MNMKKTYSGIARSTSGRLRRPERGEPTSPTASGAALKRSFEVEEDTSTNP--SPLSRRT-TNPLRSSGTSSSSRFHDLRSLNSEPMSRHASDSSSNQRSPKSSLRRVELSGGRVPETVSRRTEISIDISS----KQVDS-SPSPGIARFGLKRPEVSLQSKATDAPLHRRAEGNHSRAQEPPAPPRRADPPVSTSRIPELSQRRAEPPSPLDISAPSRRAEMHVNR--QLSDTQSPARESENSFTSAASITPTFNEYKTPPSVHEAPIRPLERSEVTSSYSSSSSSSSSIMADS---VISEIPPTMCLEKPSIDFSYVGIDAILEQMRRKAMKQGFELNIMVVGQSGLGKSTLMNTLFKS-KVSRKSFMGTAEEKIPKTIEIKSVSHDIEEKGVRMKLTVIDTPGFGDQINNENCWQPIMKFINDQYEQYLQEEINIDRKKRIPDSRVHCCIYFIPPTGHCLRPLDVEFMRRLSKVVNIVPVIAKADTLTLEERDFFKKKIREELRANGIDVYPQKEFDEDAEDRMINEKIREMIPFAVVGSDQEYQVNGRRLLGRKTKWGTIEVENIAHCEFAYLRDLLIRTHMQNIKDITSSIHYEMYRVCRLNENNTQANG--------LADHHPASHEI--", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A2R8Q8Y9-1", "uniprot_id": "A0A2R8Q8Y9_DANRE", "id": "A0A2R8Q8Y9-1", "name": "", "aln": "--MKKTTS------------------------HQALKRSFEVEDVDSSSHSSSPHTRRAPSNVQRSAMSPTSGRYYELGSNGTKP-----SDTSR----PK----------ARTPEPVPRRTELCFDIASNNNGKAIEG-SPSPGTSRFGLKRPDVLGHSKTPETQKHSVTFSKTLETIAPITRAASTIVPHASSKLPETTFRKSEPPSPGDGSA--RKPEITIS---KTSDARSHESLHHPPVTTRCP-SPNHVGRKSPGS-------DGHRPEVITSFYGN-------MAD------VGKTPVARNEKTSSEFGYVGIDAILEQMRRKAMKQGFELNIMVVGQSGLGKSTLMNTLFKS-KVSRRSVMTTEEERIPKTIEIKSISHDIEEKGVRMKLTVIDTPGFGDQINNENCWQPIMKFINTQYEQYLQEEINIDRKKRIPDSRVHCCIYFIPPTGHCLRPIDIEFMRHLSKVVNIVPVIAKADTLTLEERDFFKQKIREDLRANEIDIYPQKEFDEDAEDRMINEKIREMIPFAVVGSDQEYQVNGKRLLGRKTRWGTVEVENTTHCEFAYLRDLLIRTHMQNIKDITSSIHYEMYRVRRLNENNTKPNGQPAIHTNGVPEHEVLSHEM--", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P25342-1", "uniprot_id": "CDC10_YEAST", "id": "P25342-1", "name": "Cell division control protein 10", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MDPLSSVQPAS----YVGFDTITNQIEHRLLKKGFQFNIMVVGQSGLGKSTLINTLFASHLIDSATGDDISALPVTKTTEMKISTHTLVEDRVRLNINVIDTPGFGDFIDNSKAWEPIVKYIKEQHSQYLRKELTAQRERFITDTRVHAILYFLQPNGKELSRLDVEALKRLTEIANVIPVIGKSDTLTLDERTEFRELIQNEFEKYNFKIYPYDSEELTDEELELNRSVRSIIPFAVVGSENEIEINGETFRGRKTRWSAINVEDINQCDFVYLREFLIRTHLQDLIETTSYIHYEGFRARQLIALKENANS--------RSSAHMSSNAIQR", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * : .. ***:*:* :*:.:: :*:**::***************:**** * :. : :.** *:* :* : *. **:::.********* *:*.:.*:**:*:*: *:.:**::*:. :*:: *.*:***. :**: ..*: * :*:* :::*:::.*::***.*:*****:** *:: * :: :.:** .. : *: :*...*.:********::* ::**. : ****:*.:::**: :*:*.***::*****:*:: : ** **:* :*. :* . . . : : ", "identical_positions": 126, "similar_positions": 115, "identity": "19.84%" }, { "cls_id": "homologset.agr.MGI:1858223", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P97528-1", "uniprot_id": "CNTN6_RAT", "id": "P97528-1", "name": "Contactin-6", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MRLLWKLVILLPLINSCAG---------------------ESRFTRPIFIQEPQDVIFPLDLS--RSEIILSCTASGYPSPHYRWK--------QNGTDIDFSMTYHYRLDGGSLAISSPRTDQDIGIYQCLATNPVGTILSRKAKLQFAYIEDFETKSRSTVSVREGQGVVLLCGPPPHFGELSYDWTFNDNPLYVQEDKRRFVSQNTGNLYIAKVEPSDVGNYTCFVTNKEAHRSVQGPPTPLVQRTDGVMGEYEPKIEVRFPETIQAAKDSSVKLECFALGNPVPDISWRRLDGSPMPGKVKYSNSQATLEIPKFQQEDEGFYECVAGNLRGRNLAKGQLIFYAPPEWEQKIQNTYLSIYDSLFWECKASGNPNPSYTWLKNGERLNTE----ERIQTENGTLIITMLNVS-DSGIYQCAAENKYQTIYANAELRVLASAPDFSKNPIKKISVVQVGGDISIECKPNAFPKASISWKRGTENLKQSKRVFFLEDGSLKICNVTRSDAGSYTCVATNQFGNGKSSG-SLIVKERTVITVPPSKMDVTVGESIVLPCQVSHDPTMEVLFVWYFNGDVIDLKKGVAHFERIGGESVGDLMIRNIQLGHSGKYLCTVQTTLERLSAVADIIVRGPPGPPEDVKVEHISSTTSQLSWRPGPDNNSPIQIFTIQTRTPFSVGWQAVATVPEILNGQTYN----ATVIGLSPWVEYEFRVVAGNNIGIGEPSKPSELLRTKASIPNVAPVNINGGGGSRSELVITWEPIPEELQNGEGFGYIIMFRPVGSTTWMKEKVALVESSKFIYRNESIMP-LSPFEVKVGVYNNEGEGSLSTVSIVYSGEDEPRLAPRGTSVQSFSASDMEVSWNAIAWNRN--TGRVLGYEVLYWTDNSKESMIGKIRVSGNVTTKNITGLRANTIYFASVRAYNTAGTGPSSPPVNVTTKKSPPSQPP-ANIAWKLSNSKLCLNWEHVKTMENESEVLGYKILYRQNRQSKTHVLETNNTSAELLVPFE------EDYLIEIRTVSDGGDGSSSEEIRIPKMSSLSSVGVQILKPSTQFLTMVG-FFYCFVIQPLSR-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9JMB8-1", "uniprot_id": "CNTN6_MOUSE", "id": "Q9JMB8-1", "name": "Contactin-6", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MRLLWKLVILLPLINSCAG---------------------EGRFSRPIFIQEPQDVIFPLDLS--RSEIILTCTANGYPSPHYRWK--------QNGTDIDFGMTYHYRLDGGSLAISSPRTDQDIGIYQCLATNPVGTILSRKAKLQFAYIEDFETKTRSTVSVREGQGVVLLCGPPPHFGELSYAWTFNDSPLYVQEDKRRFVSQDTGNLYFAKVEPSDVGNYTCFVTNKEAHRSVQGPPTPLVLRTDGVMGEYEPKIEVRFPETIQAAKDSSIKLECFALGNPVPDISWKRLDGSPMPGKIKYSKSQAILEIPKFQQEDEGFYECIAGNLRGRNLAKGQLIFYAPPEWEQKIQNTYLSIYDSLFWECKASGNPNPSYTWLKNGQRLNTE----ERIQIENGTLIITMLNIS-DSGIYQCAAENKYQTIYANAELRVLASAPDFSKNPIKKISVVQVGGDISIECKPNAFPKASISWKRGTENLKQSKRVLFLEDGSLKICNVTRADAGSYTCVATNQFGNGKSSG-GLVVKERTIITVPPSKMDVTVGESIVLPCQVSHDPTMEVLFVWYFNGDIIDLKKGVAHFERIGGESVGDLMIRNIQLGHSGKYLCTVQTTLERLSAVADIIVRGPPGPPEDVKVEHISSTTSQLSWRPGPDNNSPIQIFTIQTRTPFSVGWQAVATVPEILNGQTYN----ATVVGLSPWVEYEFRVVAGNNIGIGEPSKPSELLRTKASVPNVAPGNINGGGGSRSELVITWEAIPEELQNGEGFGYIVMFRPVGTTAWMKERVALVESSKFIYRNESIMP-LSPFEVKVGVYNNEGEGSLSTVTIVYSGEDEPQLAPRGTSVQSFSASEMEVSWNAIAWNRN--TGRVLGYEVLYWTDNSKESMIGKIRVSGNVTTKNITGLRANTIYFASVRAYNTAGTGPSSLPVNVTTKKSPPSQPP-ANIAWKLSNSKLCLNWEHVKTMENESEVLGYKILYRQNRQSKTHILETNNTSAELLVPFE------EDYLIEIRTVSDGGDGSSSEEIRIPKMSSLSSTGVQISKPSTQSLSMVG-VFYCFAIHPLSR-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9UQ52-1", "uniprot_id": "CNTN6_HUMAN", "id": "Q9UQ52-1", "name": "Contactin-6", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MRLLWKLVILLPLINSSAG---------------------DGLLSRPIFTQEPHDVIFPLDLS--KSEVILNCAANGYPSPHYRWK--------QNGTDIDFTMSYHYRLDGGSLAINSPHTDQDIGMYQCLATNLLGTILSRKAKLQFAYIEDFETKTRSTVSVREGQGVVLLCGPPPHFGDLSYAWTFNDNPLYVQEDNRRFVSQETGNLYIAKVEPSDVGNYTCFITNKEAQRSVQGPPTPLVQRTDGVMGEYEPKIEVRFPETIQAAKDSSVKLECFALGNPVPDISWRRLDGSPLPGKVKYSKSQAILEIPNFQQEDEGFYECIASNLRGRNLAKGQLIFYAPPEWEQKIQNTHLSIYDNLLWECKASGKPNPWYTWLKNGERLNPE----ERIQIENGTLIITMLNVS-DSGVYQCAAENKYQIIYANAELRVLASAPDFSKSPVKKKSFVQVGGDIVIGCKPNAFPRAAISWKRGTETLRQSKRIFLLEDGSLKIYNITRSDAGSYTCIATNQFGTAKNTG-SLIVKERTVITVPPSKMDVTVGESIVLPCQVSHDPSIEVVFVWFFNGDVIDLKKGVAHFERIGGESVGDLMIRNIQLHHSGKYLCTVQTTLESLSAVADIIVRGPPGPPEDVQVEDISSTTSQLSWRAGPDNNSPIQIFTIQTRTPFSVGWQAVATVPEILNGKTYN----ATVVGLSPWVEYEFRVVAGNSIGIGEPSEPSELLRTKASVPVVAPVNIHGGGGSRSELVITWESIPEELQNGEGFGYIIMFRPVGSTTWSKEKVSSVESSRFVYRNESIIP-LSPFEVKVGVYNNEGEGSLSTVTIVYSGEDEPQLAPRGTSLQSFSASEMEVSWNAIAWNRN--TGRVLGYEVLYWTDDSKESMIGKIRVSGNVTTKNITGLKANTIYFASVRAYNTAGTGPSSPPVNVTTKKSPPSQPP-ANIAWKLTNSKLCLNWEHVKTMENESEVLGYKILYRQNRQSKTHILETNNTSAELLVPFE------EDYLIEIRTVSDGGDGSSSEEIRIPKMSSLSSRGIQFLEPSTHFLSIVIVIFHCFAIQPLI--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VN14-1", "uniprot_id": "CONT_DROME", "id": "Q9VN14-1", "name": "Contactin", "aln": "MLAKIGLLASILVLNLVGQITPQFSENLPDPDPQSGQQPQNYQPSYNKDYSPRYNPLYTGQQSADPNQFDNTLVDGQSPNTYKGYYDGRAGGGGLGGNVVGPGNNLGGLGPQYDPFNRNSIGSAGVSYRDAYTDEDNFCPEHWVSFRQTCYRFIRSPKRNWAEAKKICKAHNADLINVDNVEKHSFILKNLILQNQRQNRFFISARQTGPLNWVNDDNTQLVQIEDSFSMDEQVPLENEDLHDNRFLVQNDLNNQNINNPNQFYNSLPGTVNQRNQNNLRGFIGPNQPYGDNRYVRDRVVYAFSKKRDRWMFMPAYEIELNLFICESKVLYSSDNVNIKLDDKRPYHYGLDINDMERIPRGPYFVKQPNDTTFDVNKNRLINDVTLSCLANGYPTPSYTWYREVYVDDRLEYQKIDPLAQDRYTISGGNLIIYEPKQALDQGAYHCVAENKFGRIRSESAHLNFGFIMEFNLK-RSAETSEMNWGKSIFCDPPQHYPDVRYYWARDYFPNFVEEDQRVFVSRD-GALYFSFIETVDRANYSCTVQTLVSDTGRNGPFFPLRVTPNSNYQALIFANTFPKVFPEAPVAGDEIRLECMAFGYPIPSYNWTRQG-LPLQRNAYTINYGRVLIIQNATTNDNGEYSCTITNPRKTLMKSIYINIQMRPQFTIPLKDMIKDYNSDVTFICEAFAIPDANYTWYKNAERLDPANINRDRYIIQDNVLTIKFLEKDKDDAMYQCGAQNQLKTSFSSAQLRVLSMKPSFKKHPLESEVYAVYNGNTTIVCDPEAAPRPKFQWKKDGQVIGSGGHRRILPSGTLTISPTSRDDEGIYTCIASNQAGTDESHARVIVLQEIRFIETPPQRIVSKEHDLIFLHCEAAFDELLDIAYVWKHNGEVLKNNHDGTGRIIVDWN---RLTVHNTSMRDAGDYECVVKSAVNEISSKTSVSIEGAPGAPGGVQVIQISKTKAIIEWVDGSHNGRAIRYYNILGRTNWNRTWVNVSTHVQAREVDRYTSRQQAEVVNLTPWSAYEFSVTAVNDLGIGTPSAPSPIYSTYEDKPYIAPRNVGGGGGKIGDLTITWDPLLPQEQHSHGIHYKVFWKLKGAIEWASDEIKKQDHMGVAVVNIPLNNYYTEYEVKVQAINSVGKGPESEIAVIHSAEDMPQVAPQKPIALAYNSTCFNVTWQPIDMSRENIRGKLIGHRLKYWKTTHQEEDSVYYLSRTTRNWALIVGLQPDTYYFVKVMAYNAAGEGPESERFEERTYRKAPQKPPSSVHVYGINPSTVRVVWRYVSPSQDEEPVEGYKVRIWESDQNMITANNTIVPIGQKLESYINNLTPGKSYNMRVLAYSNGGDGRMSSPTLHFQMGKTTRNGANTRHGHNINTALILSTLLLISTFLYTSQ", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .: :*.* . : .:. : * * ::*:*. * :: . .:: *.* *.***:* * * : .** :* :.**.* * .*: * * *:*:* * .* * *..*:*:*.:* :*: * **: : . . * ::*.** *: :: * *: : * :*:**:* ***:: * **:: :*. * .**:* : . :. . :** ** .:. . . .. ...::***:*:* *:*. .* * . *: : : * * : :*:* *.* * * : . : : *:: ::: . ..: : *:* . *:. *** **.:**:. :* ::..* *.:*: . *..:***.*:*: : ::.*:****: *.*.* *::. . .*: * *.*:* *:. :.**:. : : .. : :* .*:*.* :* * * ***:*:** *. :. . ::::* .* .**.:: . : *.* *:.:.* ::: :** .**:::. ::. : :. : * ::* .: .:*.* *.*::::: :*: :.: :.*.**.* .*:* .**.*.: :.* *..*. .*: :.* ** :. * *:* : : . *. * *:.*:** *** *.* *.:*** ** ** : * . * :** *: ****. .:*.***:.: : *:..*: * :::: *: * .:.: : . * .: : :**** . *. *:*. * :::::*.** *::**: . ::.:: ::*:*:.* .*: *:::*:.: **. :*. . . *.**:.:* **..* ***:** **.* .: * :..*.:** : .: :. *.: : *.:*.. ::*. * ***: :. *. :* . .: * .: :.* :.: : *:**** *. :*.. : * : . . ::: : : ", "identical_positions": 276, "similar_positions": 381, "identity": "19.77%" }, { "cls_id": "homologset.agr.MGI:1858224", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9QZL2-1", "uniprot_id": "CHST3_RAT", "id": "Q9QZL2-1", "name": "Carbohydrate sulfotransferase 3", "aln": "----------------------------------------------MEKGLALPQDCRDLVHNLKIRGRYVLFLAFVVIVFIFIEKENKIISRVSDKLKQIPQFVADANSTDP-----ALLLSENASLLSLSELDSTFSHLRSRLHNLSLQLGIAPAMEAQGQEAVAEK----PSQQAGAGTRRHVLLMATTRTGSSFVGEFFNQQG-NIFYLFEPLWHIERTVFFQQGGASAAGSALVYRDVLKQLLLCDLYVLEPFISPPPEDHLTQFLFRRGSSRSLCEDPVCTPFVKKVFEKYHCRNRHCGPLNVTLAAEACRRKDHMALKVVRIRQLEFLQPLAEDPRLDLRVIQLVRDPRAVLASRMVAFAGKYESWKKWLS-EGQDQLSENEVQRLRGNCENIRLSAELGLRQPAWLRGRYMLVRYEDVARRPLQKAREMYRSAGIPLTPQVEDWIQKNTQAARDSSDVYSTQKNSSEQFEKWRFSIPFKLAQVVQAVCGPAMHLFGHKLAKDTASLTN--RSISLLEERGTFWVT", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O88199-1", "uniprot_id": "CHST3_MOUSE", "id": "O88199-1", "name": "Carbohydrate sulfotransferase 3", "aln": "----------------------------------------------MEKGLALPQDFRDLVHSLKIRGRYVLFLAFVVIVFIFIEKENKIISRVSDKLKQIPHFVADANSTDP-----ALLLSENASLLSLSELDSTFSHLRSRLHNLSLQLGVEPAMESQ--EAGAEK----PSQQAGAGTRRHVLLMATTRTGSSFVGEFFNQQG-NIFYLFEPLWHIERTVFFQQRGASAAGSALVYRDVLKQLLLCDLYVLEPFISPPPEDHLTQFLFRRGSSRSLCEDPVCTPFVKKVFEKYHCRNRRCGPLNVTLAGEACRRKDHVALKAVRIRQLEFLQPLVEDPRLDLRVIQLVRDPRAVLASRIVAFAGKYENWKKWLS-EGQDQLSEDEVQRLRGNCESIRLSAELGLRQPAWLRGRYMLVRYEDVARRPLQKAREMYSFAGIPLTPQVEDWIQKNTQATRDSSDVYSTQKNSSEQFEKWRFSMPFKLAQVVQAACGPTMHLFGYKLARDAASLTN--RSISLLEERGTFWVT", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q7LGC8-1", "uniprot_id": "CHST3_HUMAN", "id": "Q7LGC8-1", "name": "Carbohydrate sulfotransferase 3", "aln": "----------------------------------------------MEKGLTLPQDCRDFVHSLKMRSKYALFLVFVVIVFVFIEKENKIISRVSDKLKQIPQALADANSTDP-----ALILAENASLLSLSELDSAFSQLQSRLRNLSLQLGVEPAMEAAGEEEEEQRKEEEPPRPAVAGPRRHVLLMATTRTGSSFVGEFFNQQG-NIFYLFEPLWHIERTVSFEPGGANAAGSALVYRDVLKQLFLCDLYVLEHFITPLPEDHLTQFMFRRGSSRSLCEDPVCTPFVKKVFEKYHCKNRRCGPLNVTLAAEACRRKEHMALKAVRIRQLEFLQPLAEDPRLDLRVIQLVRDPRAVLASRMVAFAGKYKTWKKWLDDEGQDGLREEEVQRLRGNCESIRLSAELGLRQPAWLRGRYMLVRYEDVARGPLQKAREMYRFAGIPLTPQVEDWIQKNTQAAHDGSGIYSTQKNSSEQFEKWRFSMPFKLAQVVQAACGPAMRLFGYKLARDAAALTN--RSVSLLEERGTFWVT", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "B8A5X2-1", "uniprot_id": "B8A5X2_DANRE", "id": "B8A5X2-1", "name": "Sulfotransferase", "aln": "-----------------------------------------------------------------MRNKYAIIIICIV-ALVIIEKENNIISRVSDKLTLRRTQEHPVPYNAS-----NTLVATG---YNSSYLESIYGKNGS-------Q----------------------------AG-RKHILLMATTRTGSSFVGEFFNQQGDNMFYLFEPLWHVERMLSIGSSGTNGSMSVWMYRDVLQHLFLCNFSMLERFISPPPRDHVTPSLFRRESSKALCEEQVCSPVVKYIFERYHCKTRRCGPLNLTMASEACLAKHHRVIKTVRVRQLDTLRSLVEDPRLDVKLIQLVRDPRAILASRMVAFAGKYQNWKSWAV-NGEVPIEDEEVKRLEGNCNNIRISAELGLSQPKWLKKRYMLVRYEDIARYPMQKAAEMYNFTGIPMTTQARDWILKNTHAS-EANGVYSTQKNSSEQVEKWRLSIPFKLAQVVQKVCGPTMKLFGYRFIDSEQTLLN--KSFSVLEEKQFI---", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VMC4-1", "uniprot_id": "Q9VMC4_DROME", "id": "Q9VMC4-1", "name": "Sulfotransferase domain-containing protein", "aln": "--------------------------------------------------MVSLSRTSKLT--VACVGVYTTYVLFIFFLLPMLMPDPVTLQRSLVS------------------------------------------------------------------YSTSHLGDIRNLTLDAGGQPIRSMLVTFRGSGALTLLDNLAHQP-------GCYQHYAPLIAYESRSIAAK-EHHRALDELAALYNCDYNKSAEMIQ------------WGMRSPVFRRFYGAQAKICRSYSQEACWDP-------ETMAAVCKLYPFINMAVYNLRLNLLASLLERKDLN-LNIMLLVRDPRGTIYS---------RMNNKWCS-------DERDCEA-QELCGDMVSDYQMVETLTQAYPQRFSIIRYEDLFLQPDESIKQVFDFYGLPLERNRTRIQKMHPRSGYFFQSSRWKE-LSSQSAFEWISEMMVDDIGAVQDVCGQAMDLWGYRSIQDFNHFSP--ESFQPIMDKAY----", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VMC3-1", "uniprot_id": "Q9VMC3_DROME", "id": "Q9VMC3-1", "name": "Sulfotransferase domain-containing protein", "aln": "MSTGIGSSSSSTEEQQHLELSADLEACSLLGPQDPSNVDTGRTRAKQRLSLNGKRRRSRMSRRANLIGICGVSSLCILLLIATTQHRPLTTPFNQSAGRDQGASVDGGPSNSLARSAFYDRFQQQLQQQQQSSQTAVYNLTATIVDVLSAQRSRILAEMENFEYPRGGAERLTDMTPETNGTPVRSVVVTSWRSGSTFLGDILNSIP-------GNFYHYEPLLDFGIKQIRDPDDQELAVQNLKNLLNCDYADMIDYLN------------FGKTHTYLFEHNTRLWDVCREFP-RFCWRP-------AFLTRFCRLFPIQSMKTVRLRLAQAEKLLEDQSLSSVRIVLLVRDPRGTMQS---------RRHRVWCG-------GNEDCEDPRLVCQDLRDDYKTAEVLLLKYPSRFRTVRYEDLSLSPSEMTQDILQFYGLPFDPAVEEFLDTHTKVNIGGVSSTYRD-SRS-APFHWMQDLKPEEIKQIQDVCTEAMDLWGYRRIENFNNFSTTQQTFDPMVMPPPFT--", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . :. : * : :::: :*: : : : * : . : * * *: : : . : : * * : . .:* * . :.:: ******. : * . . * : : : . * .: . : *: :****: * : :: *:*: :.: . : * .* .: . :* .* :* *:*:: . : .:.. : ", "identical_positions": 34, "similar_positions": 74, "identity": "6.38%" }, { "cls_id": "homologset.agr.MGI:1858225", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q6AY56-1", "uniprot_id": "TBA8_RAT", "id": "Q6AY56-1", "name": "Tubulin alpha-8 chain", "aln": "MRECISVHVGQAGVQIGNACWELFCLEHGIQADGTFGTQASKI-NDDDSFTTFFSETGNGKHVPRAVMVDLEPTVVDEVRAGTYRQLFHPEQLITGKEDAANNYARGHYTVGKESIDLVLDRIRKLTDACSGLQGFLIFHSFGGGTGSGFTSLLMERLSLDYGKKSKLEFAIYPAPQVSTAVVEPYNSILTTHTTLEHSDCAFMVDNEAIYDICRRNLDIERPTYTNLNRLISQIVSSITASLRFDGALNVDLTEFQTNLVPYPRIHFPLVTYAPIVSAEKAYHEQLSVAEITSSCFEPNSQMVKCDPRHGKYMACCMLYRGDVVPKDVNVAIAAIKTKRTIQFVDWCPTGFKVGINYQPPTVVPGGDLAKVQRAVCMLSNTTAIAEAWARLDHKFDLMYAKRAFVHWYVGEGMEEGEFSEAREDLAALEKDYEEVGTDSFEEENEG-EEF", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9JJZ2-1", "uniprot_id": "TBA8_MOUSE", "id": "Q9JJZ2-1", "name": "Tubulin alpha-8 chain", "aln": "MRECISVHVGQAGVQIGNACWELFCLEHGIQADGTFGTQASKI-NDDDSFTTFFSETGNGKHVPRAVMVDLEPTVVDEVRAGTYRQLFHPEQLITGKEDAANNYARGHYTVGKESIDLVLDRIRKLTDACSGLQGFLIFHSFGGGTGSGFTSLLMERLSLDYGKKSKLEFAIYPAPQVSTAVVEPYNSILTTHTTLEHSDCAFMVDNEAIYDICRRNLDIERPTYTNLNRLISQIVSSITASLRFDGALNVDLTEFQTNLVPYPRIHFPLVTYAPIISAEKAYHEQLSVAEITSSCFEPNSQMVKCDPRHGKYMACCMLYRGDVVPKDVNVAIAAIKTKRTIQFVDWCPTGFKVGINYQPPTVVPGGDLAKVQRAVCMLSNTTAIAEAWARLDHKFDLMYAKRAFVHWYVGEGMEEGEFSEAREDLAALEKDYEEVGTDSFEEENEG-EEF", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9NY65-1", "uniprot_id": "TBA8_HUMAN", "id": "Q9NY65-1", "name": "Tubulin alpha-8 chain", "aln": "MRECISVHVGQAGVQIGNACWELFCLEHGIQADGTFDAQASKI-NDDDSFTTFFSETGNGKHVPRAVMIDLEPTVVDEVRAGTYRQLFHPEQLITGKEDAANNYARGHYTVGKESIDLVLDRIRKLTDACSGLQGFLIFHSFGGGTGSGFTSLLMERLSLDYGKKSKLEFAIYPAPQVSTAVVEPYNSILTTHTTLEHSDCAFMVDNEAIYDICRRNLDIERPTYTNLNRLISQIVSSITASLRFDGALNVDLTEFQTNLVPYPRIHFPLVTYAPIISAEKAYHEQLSVAEITSSCFEPNSQMVKCDPRHGKYMACCMLYRGDVVPKDVNVAIAAIKTKRTIQFVDWCPTGFKVGINYQPPTVVPGGDLAKVQRAVCMLSNTTAIAEAWARLDHKFDLMYAKRAFVHWYVGEGMEEGEFSEAREDLAALEKDYEEVGTDSFEEENEG-EEF", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P06603-1", "uniprot_id": "TBA1_DROME", "id": "P06603-1", "name": "Tubulin alpha-1 chain", "aln": "MRECISIHVGQAGVQIGNACWELYCLEHGIQPDGQMPSDKTVG-GGDDSFNTFFSETGAGKHVPRAVFVDLEPTVVDEVRTGTYRQLFHPEQLITGKEDAANNYARGHYTIGKEIVDLVLDRIRKLADQCTGLQGFLIFHSFGGGTGSGFTSLLMERLSVDYGKKSKLEFAIYPAPQVSTAVVEPYNSILTTHTTLEHSDCAFMVDNEAIYDICRRNLDIERPTYTNLNRLIGQIVSSITASLRFDGALNVDLTEFQTNLVPYPRIHFPLVTYAPVISAEKAYHEQLSVAEITNACFEPANQMVKCDPRHGKYMACCMLYRGDVVPKDVNAAIATIKTKRTIQFVDWCPTGFKVGINYQPPTVVPGGDLAKVQRAVCMLSNTTAIAEAWARLDHKFDLMYAKRAFVHWYVGEGMEEGEFSEAREDLAALEKDYEEVGMDSGDGEGEGAEEY", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P06605-1", "uniprot_id": "TBA3_DROME", "id": "P06605-1", "name": "Tubulin alpha-3 chain", "aln": "MRECISIHVGQAGVQIGNACWELYCLEHGIQPDGQMPSDKTVG-GGDDSFNTFFSETGAGKHVPRAVFVDLEPTVVDEVRTGTYRQLFHPEQLITGKEDAANNYARGHYTIGKEIVDLVLDRIRKLADQCTGLQGFLIFHSFGGGTGSGFTSLLMERLSVDYGKKSKLEFAVYPAPQVSTAVVEPYNSILTTHTTLEHSDCAFMVDNEAIYDICRRNLDIERPTYTNLNRLIGQIVSSITASLRFDGALNVDLTEFQTNLVPYPRIHFPLVTYAPVISAEKAYHEQLSVAEITNACFEPANQMVKVDPRHGKYMACCMLYRGDVVPKDVNAAIATIKTKRTIQFVDWCPTGFKVGINYQPPTVVPGGDLAKVQRAVCMLSNTTAIAEAWARLDHKFDLMYAKRAFVHWYVGEGMEEGEFSEAREDLAALEKDYEEVGMDSGDGEGEGAEEY", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P09733-1", "uniprot_id": "TBA1_YEAST", "id": "P09733-1", "name": "Tubulin alpha-1 chain", "aln": "MREVISINVGQAGCQIGNACWELYSLEHGIKPDGHLEDGLSKPKGGEEGFSTFFHETGYGKFVPRAIYVDLEPNVIDEVRNGPYKDLFHPEQLISGKEDAANNYARGHYTVGREILGDVLDRIRKLADQCDGLQGFLFTHSLGGGTGSGLGSLLLEELSAEYGKKSKLEFAVYPAPQVSTSVVEPYNTVLTTHTTLEHADCTFMVDNEAIYDMCKRNLDIPRPSFANLNNLIAQVVSSVTASLRFDGSLNVDLNEFQTNLVPYPRIHFPLVSYSPVLSKSKAFHESNSVSEITNACFEPGNQMVKCDPRDGKYMATCLLYRGDVVTRDVQRAVEQVKNKKTVQLVDWCPTGFKIGICYEPPTATPNSQLATVDRAVCMLSNTTSIAEAWKRIDRKFDLMYAKRAFVHWYVGEGMEEGEFTEAREDLAALERDYIEVGADSYAEE----EEF", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*** **::***** *********:.*****:.** : : ..::.*.*** *** **.****: :****.*:**** *.*::********:***************:*:* :. ********:* * ******: **:*******: ***:*.** :**********:********:******::*********:**:**********:*:***** **:::***.**.*:***:********:*****.*****************:*:*::* .**:**. **:***.:**** .**** ***.***** *:*******.:**: *: :*.*:*:*:*********:** *:***..*..:**.*:**********:***** *:*:*************************:**********:** *** ** * **:", "identical_positions": 322, "similar_positions": 88, "identity": "71.4%" }, { "cls_id": "homologset.agr.MGI:1858226", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I6GM79-1", "uniprot_id": "A0A8I6GM79_RAT", "id": "A0A8I6GM79-1", "name": "Sodium/myo-inositol cotransporter", "aln": "---MRAVLETADIAIVALYFVLVMCIGFFAMWKSNRSTVSGYFLAGRSMTWVAIGASLFVSNIGSEHFIGLAGSGAASGFAVGAWEFNALLLLQLLGWVFIPIYIRSGVYTMPEYLSKRFGGHRIQVYFAALSLLLYIFTKLSVDLYSGALFIQESLGWNLYVSVILLIGMTALLTVTGGLVAVIYTDTLQALLMIIGALTLMVISMMKVGGFEEVKRRYMLASPNVASILLTHN--LSNTNSCMVHPKADALKMLRDPTDEDVPWPGFILGQTPASVWYWCADQVIVQRVLAAKNIAHAKGSTLMAGFLKLLPMFIIVVPGMISRILFVDDIACINPEHCMQVCGSRAGCSNIAYPRLVMELVPVGLRGLMMAVMIAALMSDLDSIFNSASTIFTLDVYKLLRNNASSRELMIVGRIFVAFMVVISIAWVPIIVEMQGGQMYLYIQEVADYLTPPVAALFLLAIFWKRCNEQGAFYGGMAGFVLGAIRLILAFTYRAPECDQPDNRPSFIKDIHYMYVATALFWITGLITVIVSLLTPPPTKDQIRTTTFWSKKTVVTKESCSQKDEPYKMQEKSILRCSENSEVVSHTIPNGKSEDSIKGLQPEDVNLLVTCREEGNPVASMGHSEAETPVDAYSNGQAALMGERAREKETESRSRYWKFIDWFCGFKSRSLSKRSLRDSMDEEAVCLQMLEETPRVRVILNIGLFAVCSLGIFMFVYFSL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9JKZ2-1", "uniprot_id": "SC5A3_MOUSE", "id": "Q9JKZ2-1", "name": "Sodium/myo-inositol cotransporter", "aln": "---MRAVLEAADIAVVALYFILVMCIGFFAMWKSNRSTVSGYFLAGRSMTWVAIGASLFVSNIGSEHFIGLAGSGAASGFAVGAWEFNALLLLQLLGWVFIPIYIRSGVYTMPEYLSKRFGGHRIQVYFAALSLLLYIFTKLSVDLYSGALFIQESLGWNLYVSVILLIGMTALLTVTGGLVAVIYTDTLQALLMIIGALTLMVISMVKIGGFEEVKRRYMLASPDVASILLKYN--LSNTNACMVHPKANALKMLRDPTDEDVPWPGFILGQTPASVWYWCADQVIVQRVLAAKNIAHAKGSTLMAGFLKLLPMFIIVVPGMISRIVFADEIACINPEHCMQVCGSRAGCSNIAYPRLVMTLVPVGLRGLMMAVMIAALMSDLDSIFNSASTIFTLDVYKLIRKSASSRELMIVGRIFVAFMVVISIAWVPIIVEMQGGQMYLYIQEVADYLTPPVAALFLLAIFWKRCNEQGAFYGGMAGFVLGAVRLILAFTYRAPECDQPDNRPGFIKDIHYMYVATALFWITGLITVIVSLLTPPPTKDQIRTTTFWSKKTLVTKESCSQKDEPYKMQEKSILQCSENSEVISHTIPNGKSEDSIKGLQPEDVNLLVTCREEGNPVASMGHSEAETPVDAYSNGQAALMGEREREKETENRSRYWKFIDWFCGFKSKSLSKRSLRDLMDEEAVCLQMLEETPQVKVILNIGLFAVCSLGIFMFVYFSL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P53794-1", "uniprot_id": "SC5A3_HUMAN", "id": "P53794-1", "name": "Sodium/myo-inositol cotransporter", "aln": "---MRAVLDTADIAIVALYFILVMCIGFFAMWKSNRSTVSGYFLAGRSMTWVAIGASLFVSNIGSEHFIGLAGSGAASGFAVGAWEFNALLLLQLLGWVFIPIYIRSGVYTMPEYLSKRFGGHRIQVYFAALSLILYIFTKLSVDLYSGALFIQESLGWNLYVSVILLIGMTALLTVTGGLVAVIYTDTLQALLMIIGALTLMIISIMEIGGFEEVKRRYMLASPDVTSILLTYN--LSNTNSCNVSPKKEALKMLRNPTDEDVPWPGFILGQTPASVWYWCADQVIVQRVLAAKNIAHAKGSTLMAGFLKLLPMFIIVVPGMISRILFTDDIACINPEHCMLVCGSRAGCSNIAYPRLVMKLVPVGLRGLMMAVMIAALMSDLDSIFNSASTIFTLDVYKLIRKSASSRELMIVGRIFVAFMVVISIAWVPIIVEMQGGQMYLYIQEVADYLTPPVAALFLLAIFWKRCNEQGAFYGGMAGFVLGAVRLILAFAYRAPECDQPDNRPGFIKDIHYMYVATGLFWVTGLITVIVSLLTPPPTKEQIRTTTFWSKKNLVVKENCSPKEEPYKMQEKSILRCSENNETINHIIPNGKSEDSIKGLQPEDVNLLVTCREEGNPVASLGHSEAETPVDAYSNGQAALMGEKERKKETDDGGRYWKFIDWFCGFKSKSLSKRSLRDLMEEEAVCLQMLEETRQVKVILNIGLFAVCSLGIFMFVYFSL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M2BF94-1", "uniprot_id": "A0A8M2BF94_DANRE", "id": "A0A8M2BF94-1", "name": "Sodium/myo-inositol cotransporter", "aln": "MLKTGPAMEAADITVVALYFVLVLVIGLLAMWKANHSTVSGYFLAGRTMNWAVIGASLFVSNIGSEHFIGLAGSGAASGFAVAAWEFNALLLLQLLGWVFIPVYIHSGVYTMPEYLSKRYGGKRLKIYFAGLSLLLYIFTKLSVDLYAGALFIQESLGWNLYLSIILLISMTALLTVTGGLVAVIYTDTLQAVLMIGGALTLTIISLIKVGGLEGVREKYMEAVPNVTAILASSNFSFEYTNSCRIYPKPDSLKLLRGPLDEDIPWPGFLLGQTPSSIWYWCADQVIVQRVLAAKNIAHAKGSTLMAGVLKILPMFIIVIPGMISRILFPDELACIGPEHCMAVCGSQAGCSNIAYPRLVMSVMPVGLRGLMMAVMIAALMSDLDSIFNSASTIFTLDIYKMLRARASSRELVVIGRIFVIFMVAISIAWVPVIIEMQGGQMYLYIQEVAGYLTPPIAALFLLGVFWKRCNEIGAFCGGMTGFVLGTTRLLLGFIYREPKCDQPDERPAFITRIHYMYIAAGLFWISGLVAVVVSLCTTPPDEERIKRTTMWGLRKLR-RLVVTEREEMYKLTN-----GSGNGILKKDVPEDVQKEKCLDG---ADIKLLLPSPCDQDPTTPN--TEASTPMELYGNGHAKLV--KQKDESQSDDESCLQVIDWICCHKEKTSVV-EPKFIKEDEETIREMLHEPPKIKLLLNICLVLICLLGIFMFVYFSL", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "B8JHU7-1", "uniprot_id": "B8JHU7_DANRE", "id": "B8JHU7-1", "name": "Sodium/myo-inositol cotransporter", "aln": "---MASTMEAADIIVVAMYFVLVLCFGFFSMWRANRGTVSGYFLAGRSMNWFVIGASLFVSNIGSEHFIGLAGSGAASGLAVGAWEFNAILLLQLLGWVFIPVYIHSGVYTMPEYLSKRFGGNRLKIYFASLTLLLYIFTKLSVDLYSGALFIQESLGWNLYLSIILLITLTALLTVTGGLVAVIYTDTLQAFLMISGALCLMAISLVKVGGLEGLRTKYMNALPNITFITLEN--NLTYSNSCHVNPKADSFKLLRSPLDKDLPWPAFLLGQTPASIWYWCADQVIVQRVLAARNIAHAKGSTLLAGVLKVLPMFIIVIPGMISRVLFADELACIGPEHCMQVCNSRAGCTNTAYPRLVMNIMPVGLRGLMMAVMLAALMSDLDSIFNSASTIFTLDIYKMIRHQASSKELMVVGRLFVVLIVAISIAWVPFVIEMQGGQMFLYIQEVSDYLTPPIAALFLLGVLWKRCNETGAFWGGFVGLILGIVRLILAFVYREPDCDSVDDRPAFIKDVHFMYVAAVLFWVSGFVMVVVSLCTNPPSKEQISKTTLWGLRNRN-QPADT------KAKG-----GNG------------KLEQTLDG---VEFQPLPP------EMLPN--GHLEAPHTHR----------QATEHAARNKGRCVKCLGWFCGYNEHSEES-DSPFE-DDGRSVHEMLKESAQNKTALNIGLLLVCALGIFLYVYFSL", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ..:::*** :**:**:**: :*:::**::*:.**********:*.* .**************************:**.******:************:**:*************:**:*:::***.*:*:************:**************:*:**** :*********************.*** *** * **::::**:* :: :** * *::: * : :*:* : ** :::*:**.* *:*:***.*:*****:*:****************:**********:**.**:*******:******::* *::***.***** **.*:***:* ******* ::************:*********************:**::* ***:**:::**:** ::*.*******.::*******:******:.*****:******.::****** *** **:.*::** **:*.* ** *.**. *:**.**. :*:**:*: ***::*:: *:*** * ** :::* **:*. :. : : * . : *. :.* :.: * . . . .:* : .. . : :.*:* .:.:: . :: :**.*. : : *** *. :* ****::*****", "identical_positions": 398, "similar_positions": 168, "identity": "55.05%" }, { "cls_id": "homologset.agr.MGI:1858227", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9QUK0-1", "uniprot_id": "CDKL2_MOUSE", "id": "Q9QUK0-1", "name": "Cyclin-dependent kinase-like 2", "aln": "MEKYENLGLVGEGSYGMVMKCRNKDSGRIVAIKKFLESDDDKMVKKIAMREIKLLKQLRHENLVNLLEVCKKKKRWYLVFEFVDHTILDDLKLFPNGLDYQVVQKYLFQIINGIGFCHSHNIIHRDIKPENILVSQSGVVKLCDFGFARTLAAPGEVYTDYVATRWYRAPELLVGDVKYGKAVDIWAIGCLVIEMLMGQPLFPGESDIDQLHHIMTCLGNLIPRHQELFYKNPVFAGVRLPEVKDAEAEPLESRYPKLPEAVISLAKKCLHIDPDKRPFCADLLRHDFFQMDGFAERFSQELQLKIEKDARNNSLPKKSQNRKKEK--DDALGEERKTLVVQDTNADPKIKDSKVFKVKGSKIDVEKMEKGSRASNANCLHDNGTNH-KGLASTSLRDCSNVNIDHSRNPGTAIPPLTHNLSAVAPGINAGMG--TIPGVQNYRVDEKTKKYCNPFVKPNQPPPAGIYNMNVSTSVSGEKYLLQANKKRKEYPKADVRLPELNYNHLPELRALEGIARNSRLIKKENKCLSESRIPSLAAIDLHVSSVASHQGAGSPLSDDSEADLPRMEHQH", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q5XIT0-1", "uniprot_id": "CDKL2_RAT", "id": "Q5XIT0-1", "name": "Cyclin-dependent kinase-like 2", "aln": "MEKYENLGLVGEGSYGMVMKCRNKDSGRIVAIKKFLESDDDKMVKKIAMREIKLLKQLRHENLVNLLEVCKKKKRWYLVFEFVDHTILDDLKLFPNGLDYQVVQKYLFQIINGIGFCHSHNIIHRDIKPENILVSQSGVVKLCDFGFARTLAAPGEVYTDYVATRWYRAPELLVGDVKYGKAVDIWAIGCLVIEMLMGQPLFPGESDIDQLHHIMTCLGNLIPRHQELFYKNPVFAGVRLPEIKDIEAEPLESRYPKLPEVVISLAKKCLHIDPDKRPLCADLLHHDFFQMDGFAERFSQELQLKIEKDARNNSLPKKFQIRKKEK--DDALGEERKTLVVQDTNADPKTKDSKVLKVKGSKIDVEKTEKGTRASNGSCLHDNGTSH-KGLSSTSLRDCSNVTIDHPRNPGTAIPPLTHNLSAVAPGINAAMG--TIPGVQNYRVDEKTKKYCNPFVKPSQPSPSGIYNMNVSASVSN----CPLPRKSKHSPPLDL-----------------AVSMGARRVKLYLETESET----------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q92772-1", "uniprot_id": "CDKL2_HUMAN", "id": "Q92772-1", "name": "Cyclin-dependent kinase-like 2", "aln": "MEKYENLGLVGEGSYGMVMKCRNKDTGRIVAIKKFLESDDDKMVKKIAMREIKLLKQLRHENLVNLLEVCKKKKRWYLVFEFVDHTILDDLELFPNGLDYQVVQKYLFQIINGIGFCHSHNIIHRDIKPENILVSQSGVVKLCDFGFARTLAAPGEVYTDYVATRWYRAPELLVGDVKYGKAVDVWAIGCLVTEMFMGEPLFPGDSDIDQLYHIMMCLGNLIPRHQELFNKNPVFAGVRLPEIK--EREPLERRYPKLSEVVIDLAKKCLHIDPDKRPFCAELLHHDFFQMDGFAERFSQELQLKVQKDARNVSLSKKSQNRKKEKEKDDSLVEERKTLVVQDTNADPKIKDYKLFKIKGSKIDGEKAEKGNRASNASCLHDSRTSHNKIVPSTSLKDCSNVSVDHTRNPSVAIPPLTHNLSAVAPSINSGMGTETIP-IQGYRVDEKTKKCSIPFVKPNRHSPSGIYNINVTTLVSG--------------PPLSD-------------------DSGADLPQMEHQH--------------------------------------------", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*************************:*****************************************************************:********************************************************************************************:******* **:**:*****:******:*** ************* ************:* * **** *****.*.**.**************:**:**:********************::***** **.** * ***** **:* **************** ** *::*:****** ** ***.****..****. *.* * :.****:*****.:**.***..**************.**:.** *** :*.********* . *****.: .*:****:**:: **. * . .: : : ", "identical_positions": 404, "similar_positions": 53, "identity": "70.51%" }, { "cls_id": "homologset.agr.MGI:1858229", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q5U2R5-1", "uniprot_id": "PPR3C_RAT", "id": "Q5U2R5-1", "name": "Protein phosphatase 1 regulatory subunit 3C", "aln": "-------------------------------------------------------------MSCTRMIHVLDPRPLTSSVMPVDMAMR-----------------------------------------------------------------------ICLAHSPPLKSFLGPYNGLQRRHFVN-KPKPLKPCLSVKQ-----------------------EAK-SQKEWKSPHSQ-----------AKKRVVFADSKGLSLTAIHVFSDLP----------------------------------------------------------------EEPAWDLQFDLLDLNDISSSLKLHEEKN-----------------------------LVFDFPQPSS-DYLSFRDRFQKNFVCLENCSLQDRT------------------------------------------VTGTVKVKNVSFEKKVQVRITFDTWKTYTDVDCVYLKN----VYGSSDSDTFSFAIDLPRVIPTEEK----IEFCISYHAN-----GRVFWDNNEAQNYRIVHVQWKPDGVQ--TQVAPKDCAFQQVPLKTELEPTVFG--SPRLASGLFPEWQSWGRVENLASYR", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q7TMB3-1", "uniprot_id": "PPR3C_MOUSE", "id": "Q7TMB3-1", "name": "Protein phosphatase 1 regulatory subunit 3C", "aln": "-------------------------------------------------------------MSCTRMIHVLDPRPLTSSVMPVDMAMR-----------------------------------------------------------------------ICLAHSPPLKSFLGPYNGFQRRNFVN-KLKPLKPCLSVKQ-----------------------EAK-SQSEWKSPHNQ-----------AKKRVVFADSKGLSLTAIHVFSDLP----------------------------------------------------------------EEPAWDLQFDLLDLNDISSSLKLHEEKN-----------------------------LVFDFPQPST-DYLSFRDRFQKNFVCLENCSLQDRT------------------------------------------VTGTVKVKNVSFEKKVQVRITFDTWKTYTDVDCVYMKN----VYSSSDSDTFSFAIDLPRVIPTEEK----IEFCISYHAN-----GRIFWDNNEGQNYRIVHVQWKPDGVQ--TQVAPKDCAFQQGPPKTEIEPTVFG--SPRLASGLFPEWQSWGRVENLTSYR", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9UQK1-1", "uniprot_id": "PPR3C_HUMAN", "id": "Q9UQK1-1", "name": "Protein phosphatase 1 regulatory subunit 3C", "aln": "-------------------------------------------------------------MSCTRMIQVLDPRPLTSSVMPVDVAMR-----------------------------------------------------------------------LCLAHSPPVKSFLGPYDEFQRRHFVN-KLKPLKSCLNIKH-----------------------KAK-SQNDWKCSHNQ-----------AKKRVVFADSKGLSLTAIHVFSDLP----------------------------------------------------------------EEPAWDLQFDLLDLNDISSALKHHEEKN-----------------------------LILDFPQPST-DYLSFRSHFQKNFVCLENCSLQERT------------------------------------------VTGTVKVKNVSFEKKVQIRITFDSWKNYTDVDCVYMKN----VYGGTDSDTFSFAIDLPPVIPTEQK----IEFCISYHAN-----GQVFWDNNDGQNYRIVHVQWKPDGVQ--TQMAPQDCAFHQTSPKTELESTIFG--SPRLASGLFPEWQSWGRMENLASYR", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F1QTC2-1", "uniprot_id": "F1QTC2_DANRE", "id": "F1QTC2-1", "name": "Protein phosphatase 1 regulatory subunit 3C", "aln": "-------------------------------------------------------------MSSTRVLHILSP-PMPGPVMPVDVAVQ-----------------------------------------------------------------------LYITHSPPLRNFLSSYEDYRTRNLVSNCCKPLRPCLSSRA-----------------------QLEHSCRSWQNPKSK-----------TKKKVVFADSKGMSLTAVHVFSTFDNK--------------------------------------------------------------ETATSELQFDLEDLEELKNTLHINSVQS-----------------------------RILDFLQPAA-DYLDFRSHLLKNLVCLENCTLQERA------------------------------------------LTGTIKVRNLAYEKSVHVRITFDSWKSFEDIECTFMNN----VYGCQDTDTFSFAIELPGYVPPQNK----VEFCISFRTG-----EQIYWDNNDGRNYGLISTSWQQNNKLNSSTQTKKSDEFRKKSSKKTQEKGVFKCKSSLQSNGIFPNWQSWGQIAATGPYW", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q6P950-1", "uniprot_id": "PR3CB_DANRE", "id": "Q6P950-1", "name": "Protein phosphatase 1 regulatory subunit 3C-B", "aln": "-------------------------------------------------------------MNCTRVLQILNPRPMPSPIMPVDVAMR-----------------------------------------------------------------------ICLAHSPPLRSFLSSYEDCKSRNLVN-QYKPLRSCISSKT-----------------------EDDTANITWKSPETK-----------AKKKVVFADSKGMSLTAVHVFKEFE----------------------------------------------------------------EDLMLDLQFELSDLEDAIVGLKAEKEKN-----------------------------FSLGFPQPAA-DYLDFRNRLKKNLVCLENCIIQERS------------------------------------------VTGTVKVSNVSFEKVVHVRITFDSWKSHTDIPCTYMNN----VYGCEDVDTFSFSIDLPSFVAPHEQ----VEFCLSYKTH-----DMTYWDNNDGKNYKLVHT---ENDSSQASVIQNATTDFKAQGKRPDMEFDQFG--SPRTSSGFFPEWQSWGHIENNTPYW", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VUF3-1", "uniprot_id": "Q9VUF3_DROME", "id": "Q9VUF3-1", "name": "Protein phosphatase 1 regulatory subunit", "aln": "-----MISHSPPIFSHSPPVSFLADFMSGHPRQSLNYNDEPNRASRYCRPQVITLASKAMVNNASAAVQGQGPSQQKAGATPLGVGSRSGRSY-----------------------------------------------------------------LERMASAPLLTNQPKSCLSRKSCLHKSQNTTASSADLSPTD-----------------------TDVADSASHSCICSKDSDSNGEVSRGPKKHVIFADDEGLSLTEVRVMSEPS-------------------------------------------------------------------NVPPYWSMKFLEQITQGLVSPHPPDQ----------------------------WTVDFKQPAS-DYLSFRQKIERDFVSLENVIVKDEES----------------------------------------IVVGTIKVKNIDFQKEIIVRVTWDDWKSQQDIFCTYARAYGPATCAHVVFDTFSFKITLP---PSSKR----LEFCICYRTN-----ETEYWDNNDGKNYTISKRSPFYYNALSPYDKGQNRNSSQQIRSTLTDALAKVQD-------------QNGWHQEPHTPYW", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P40036-1", "uniprot_id": "GIP2_YEAST", "id": "P40036-1", "name": "GLC7-interacting protein 2", "aln": "MYIKAEQKPQQFERKNEKLDRNKNQQLPDLETDFKGYRVNSDLYNKERDGSTEETLNSLKFLHKPQRVTQMRANRFPEEEVQRNTDLNKRIFSAGNDENVDNESGWSKIAAAKNHTSVESLNGSTRPPFKIELPPLSPKSTVPKSFQAEYPEAKSPGNDMNFEYDEEILIPFAPPVYKKSGELLKSSLKRRSKSLPTTP-------GIRSGNGVQARDGSPMLIRSKSVHFDQAAPVKYFAEDESPINVNKTEQHDNCLSFKHKPVNLMVDPEEE------TKMLSSG------------------LETTSIDDDLTTVAPKGFAHPAKISNPNNGKGTNNTKLRKSKRFQNLLKNRTDMPPSKSNKKFVNGGGAHEISDR---NSKNYHVVGLYSKNFPILSNKNPKSLKLNIFINLSQNKKVFLQELSLYIHRDNNYFSNSSSFYNIPNSHNGNDCNGVAKGYNAGCTRLIAGRILVKNIFYDKRVVVRYTWDSWRTTHEVECVYISD-GDGILPGTNMDIFHFIIDDVSKVDPR----GKLEFCIHYSTR-NDYEREEYWDNNNGNNYKVDVVMDG--------FNDPFAAAA------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P40187-1", "uniprot_id": "PIG2_YEAST", "id": "P40187-1", "name": "GSY2-interacting protein PIG2", "aln": "---MATTTQPQNILMDEPLNLPNN---SAHNNNYGNINANIRTFAGMSMHMHPARLNSLEFLHKPRRLSNVKLHRLPQDELQRNTDMNKGMYFNGKQVHAHHPFINSGANFNAHHQDVSKLG--------------------------EEEDEISPLSHDNFQYESEENGNPSPPIYKKSGELVKSSLKRRSKSLPITPKSIFNKTGSKSKHVNLDHVDTRLLQRSKSVHFDRVLPIKLFNENEKPIDVGKQMVQQDVLNFKHKPLTRLSALNGGSDSVPIEDLLSENNQNEYGDTWLQNPKGVFLFGTNSNNRRNKKKKFKLSDDDSDIENDNDSDDAINRLVRQQDKDQAHLAHGLKNLLINDDDDYLETRTNSAKSGANLFIGNSKRIVGLYNKNFPILSDRNRKSLKLNIFLNLSRGRPVFLQEITLLTGFHN---------------------------------MVIIGKVFVKNIYFDKKIIVRYTWDAWRTFHESECVYFSN-ANGILPGSNMDIFKFSIDDIHNPNDKDSNISQLEFCIQYLTWGVDRSRKEYWDNNDSANYKIDVVTNETRTGPTTDVNDNYEMKHSLFRNPFH----------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . : . . : . : . . : . * : .:. . : : . . .* : : .:: .: :: . ::: : * : * *: ::* : :* *:* *:. : *.: * * * * :***: : : :****:. ** : ", "identical_positions": 24, "similar_positions": 55, "identity": "3.76%" }, { "cls_id": "homologset.agr.MGI:1858230", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZAS8-1", "uniprot_id": "D3ZAS8_RAT", "id": "D3ZAS8-1", "name": "Spliceosome associated factor 3, U4/U6 recycling protein", "aln": "--------------------------------MATATASSASEPEVEPQARPEAEGEEDEAKPAGVGRKVLS---SAETAKAKGPEREVHQEGVSESDGDEEDAAMASSAESSAGEDEW------------------EYDEEEEKNQLEIER-LEEQLSINGYDYNCHVGLIRLLRLEGELNKVRMARQKMSEIFPLTEELWLEWLHDEISMAVDGLDRERVYELFERAVKDYICPNIWLEYGQYSVGGIGQKGGLEKVRSVFERALSSVGLHMTKGLAIWEAYREFESAIVEAARPIAAFLSPSDREQTFDSQLERVHSLFRRQLAIPLYEMEATFAEYEEWSEEPIPESVLQSYQKALGQLEKYKPYEEALLQAEAPRLAEYQAYIDFEMKVGDPARIQLIFERALVENCLVPDLWIRYSQYLDRQLKVKDLVLSVHSRAVRNCPWTVALWSRYLLAMERHGLDHQMISATFENALSAGFIQATDYVEIWQVYLDYLRRRVDFRQDSSKELEELRSMFTRALEYLQQEVEERFSESGDPSCLIMQSWARVEARLCNNMQKARELWDSIMTR-GNAKYANMWLEYYNLERAHGDTQHCRKALHRAV-QCTSDYPEHVCEVLLTMERTEGTLEDWDLAIQKTETRLARVNEQRMKAAEKEAALVQQEEEKAEQRKKVRAEKKALKKKK-TRGADKRKAGEDDDERECGEEEEEQPSKRRRMENSL-ASGVASAKEEETKLSGKCL--TIDVAPP--SKQKEKAASLKRDMPKVAHDSSKDSVTVFVSNLPYSIEEPEVKLRPLFEACGEVVQIRPIFSNRGDFRGYCYVEFKEEKSAQQALDLDRKNVEGRPMFVSPCVDKSKNPDFKMFRYSTTLEKHKLFISGLPFSCTKEELEGICKAHGTVKDLRLVTNRAGKPKGLAYVEYENESQASQAVLKMDGMTIKENVIKVAISNPPQRKVPEKPEVRTAPGAPMVPRQMYGARGKGRTQLSLLPRALQR-QGAAPQAENGPAPGLAATT-----SVATEAPKMSNADFAKLLLRK", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9JLI8-1", "uniprot_id": "SART3_MOUSE", "id": "Q9JLI8-1", "name": "Spliceosome associated factor 3, U4/U6 recycling protein", "aln": "--------------------------------MATTAASSASEPEVEPQAGPEAEGEEDEAKPAGVQRKVLSGAVAAEAAEAKGPGWDLQREGASGSDGDEED-AMASSAESSAGEDEW------------------EYDEEEEKNQLEIER-LEEQLSINGYDYNCHVELIRLLRLEGELSRVRAARQKMSELFPLTEELWLEWLHDEISMAMDGLDREHVYELFERAVKDYICPNIWLEYGQYSVGGIGQKGGLEKVRSVFERALSSVGLHMTKGLAIWEAYREFESAIVEAAR------------------LEKVHSLFRRQLAIPLYEMEATFAEYEEWSEEPMPESVLQSYQKALGQLEKYKPYEEALLQAEAPRLAEYQAYIDFEMKIGDPARIQLIFERALVENCLVPDLWIRYSQYLDRQLKVKDLVLSVHSRAVRNCPWTVALWSRYLLAMERHGLDHQTISATFENALSAGFIQATDYVEIWQVYLDYLRRRVDFRQDSSKELEELRSMFTRALEYLQQEVEERFSESGDPSCLIMQSWARVEARLCNNMQKARELWDSIMTR-GNAKYANMWLEYYNLERAHGDTQHCRKALHRAV-QCTSDYPEHVCEVLLTMERTEGTLEDWDLAIQKTETRLARVNEQRMKAAEKEAALVQQEEEKAEQRKKVRAEKKALKKKKKTRGADKRREDEDE-ENEWGEEEEEQPSKRRRTENSL-ASGEASAMKEETELSGKCL--TIDVGPP--SKQKEKAASLKRDMPKVAHDSSKDSVTVFVSNLPYSIEEPEVKLRPLFEVCGEVVQIRPIFSNRGDFRGYCYVEFGEEKSAQQALELDRKIVEGRPMFVSPCVDKSKNPDFKVFRYSTTLEKHKLFISGLPFSCTKEELEDICKAHGTVKDLRLVTNRAGKPKGLAYVEYENESQASQAVMKMDGMTIRENVIKVAISNPPQRKVPEKPEVRTAPGAPMLPRQMYGARGKGRTQLSLLPRALQR-QGAAPQAENGPAPGPAVAP-----SVATEAPKMSNADFAKLLLRK", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q15020-1", "uniprot_id": "SART3_HUMAN", "id": "Q15020-1", "name": "Spliceosome associated factor 3, U4/U6 recycling protein", "aln": "--------------------------------MATAAETSASEPEAESKAGPKADGEEDEVKAARTRRKVLSRAVAAATYKTMGPAWDQQEEGVSESDG--DEYAMASSAESSPGEYEW------------------EYDEEEEKNQLEIER-LEEQLSINVYDYNCHVDLIRLLRLEGELTKVRMARQKMSEIFPLTEELWLEWLHDEISMAQDGLDREHVYDLFEKAVKDYICPNIWLEYGQYSVGGIGQKGGLEKVRSVFERALSSVGLHMTKGLALWEAYREFESAIVEAAR------------------LEKVHSLFRRQLAIPLYDMEATFAEYEEWSEDPIPESVIQNYNKALQQLEKYKPYEEALLQAEAPRLAEYQAYIDFEMKIGDPARIQLIFERALVENCLVPDLWIRYSQYLDRQLKVKDLVLSVHNRAIRNCPWTVALWSRYLLAMERHGVDHQVISVTFEKALNAGFIQATDYVEIWQAYLDYLRRRVDFKQDSSKELEELRAAFTRALEYLKQEVEERFNESGDPSCVIMQNWARIEARLCNNMQKARELWDSIMTR-GNAKYANMWLEYYNLERAHGDTQHCRKALHRAV-QCTSDYPEHVCEVLLTMERTEGSLEDWDIAVQKTETRLARVNEQRMKAAEKEAALVQQEEEKAEQRKRARAEKKALKKKKKIRGPEKRGADEDD-EKEWGDDEEEQPSKRRRVENSIPAAGETQNVEVAAGPAGKCA--AVDVEPP--SKQKEKAASLKRDMPKVLHDSSKDSITVFVSNLPYSMQEPDTKLRPLFEACGEVVQIRPIFSNRGDFRGYCYVEFKEEKSALQALEMDRKSVEGRPMFVSPCVDKSKNPDFKVFRYSTSLEKHKLFISGLPFSCTKEELEEICKAHGTVKDLRLVTNRAGKPKGLAYVEYENESQASQAVMKMDGMTIKENIIKVAISNPPQRKVPEKPETRKAPGGPMLLPQTYGARGKGRTQLSLLPRALQRPSAAAPQAENGPAAAPAVAA-----PAATEAPKMSNADFAKLFLRK", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "B3DJT0-1", "uniprot_id": "SART3_DANRE", "id": "B3DJT0-1", "name": "Spliceosome associated factor 3, U4/U6 recycling protein", "aln": "-----------------------------------MAATGNEEQTLLPDIEEEAEGMEREMESE-----------------------DDEEEGMG--------------VEHSEEEDEE------------------DTSEDERENEAEIQR-LEEQLSINAFDYNCHVDLIKLLRQEGKLHRLRKARQKMSELFPLTEEIWLDWLKDEIRITEDESDREKVYELFERAIKDYVCPEIWLEYVQYSIGGMGAQGGIERVRSIFERALTAVGLHMTKGASIWEAYREFEIVILSTVQPPPGTVPSQEQQELLSAQLERIHTLFRRQLAVPLMDMEGTYAEYSDWADDGVPETVTHQYRRALQQMEKGKPYEEALLVSEPPKLAEYQSYIDFEIKEGDPARVQIIFERALAENCLVPDLWIKYTTYLDRQLKIKDLVLSAHERAVRNCPWTMGLWKSYLLALERHGADHQTVKDVFEKALNAGFIQATDYVEIWQSYLDYLRRRVDFSKEWSRELDELRAAFSRSLEYLKQDVEERFSESGDLSCTLMQIWARIEALHCKNMQKARELWDSIMTK-GNAKYANMWLEYYNLERSYGDAAHCRKALHRAV-QCTSDYPEHVCDVLLNFERVEGSLEDWDAAVQKTETKLNRVCEQRARVAEKEALHARQEEEKAEQRRKVKADKKAQKKGQKANRTGDKRKAEDDDEEEWG-EEAELPSKRLRGEDDFDSTVTEELMETESGLFGRRAPPARKTEPPGFRKNQQGAPEPQRQPHDMPKEQRKDENCVFVSNLTFNMEDPEGKLRTLFQGCGTIQQVRPVFTAKGTFRGYCYVQFEDRLAVPEALKMDRQEVDGRPMYVSPCVDKNKNPDFKVFKYKTSMEKHKIFISGLPYSATKETLEDLCKEHGTIRAIRIVTNRSGKSKGLAYVEFEDEAQASQAVLKMDGTMLENFTLSVAISNPPGRRMKDEAAPSRFLG-AAMPRQLQGARGKGRTQISLLPRSLYRQSTPDAKAENGTISAPHATVTDGETSLDTQTKSLSNEDFARMLLKK", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9W4D2-1", "uniprot_id": "RNP4F_DROME", "id": "Q9W4D2-1", "name": "RNA-binding protein 4F", "aln": "MDADKQLERQLEKELDEMPAEDLDDDAYDEYDLIVIPDQGKGSPQQGHSESPQQEEEHKSEELRQRSRPTWPPSSAGGDMTTIELISSDDEPSVEETEGGNAAGRGRARNDSSSSSDDVGVIEGSELESNSEVSSDSDSDSDNAGGGNQLERSYQELNALPSKKFAQMVSLIGIAFKLNDLEKIESSVLELQNLATVPAHVWLKYLKARLVVTQTDEERKAFEEQCAKALGYYYSIPLSEYVVNYLVDQGNVQNHVLWAKLLADYDVERPDFGDKLRSLISTITDENEAAAFVEMLQK--------------HCVTWTCNVEQRQMIKSVVDKFKQHLDETTRGWDWSEQHKAHVYDVETLSLDDDLKNAVIRFIFERSVAKFPIVDVLWLSYIEFIQFEGVTVPENEDENEVTAEMVAKRAKRLG-KGFLRNTELDLANRGVRSHP-SVQLNHRFLDLMERSDFELAEVDEEIRLILQRIVTDMDMTVELHLDYLAYRIRNTNASDE--QQVASLRAAFN----HAWEELTVLYGDQADTRYEVLQLWAQVEYTQLGSPDNGREIWRQIMGYPGSSIRGLLWLNFAQMESEYNGGHGTRDVLRKALSQPVLENGLMVQEFFRRYERCYGTYES-IAACQALDLPVEYVKPRSRIKPNSQSAYPRQQKLKPRQ-QQQQTNREPLNREQRRRQAHEQQQQQQQQQKHGIKKSRTEPSGG-------------------------------ATSPP---SKVKGPANAEAKESNFKYSPNMEINKIFVRNLHPACSKEE--LHELFSPFGTIKDVRLVHKLNKQFKGIAYVEFEKPGEAQRAVAG-RDGCLFKGMNISVAISNPPPRGTSAVKPSVAPKRR---------VPTSLIPTTLVRQEVAAKKLRLLLPEPG--------DISSTSASVDVAIKREANGEEQ---------KGDVQERDEQKGEEQKGEEQKGEEPKGEEQKGDDQIGEEQSGVEQ-KGDEKKEEEMPAAVP-----------------KSNDDFRKLFLKD", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus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identical_positions": 107, "similar_positions": 319, "identity": "10.23%" }, { "cls_id": "homologset.agr.MGI:1858231", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D4A828-1", "uniprot_id": "D4A828_RAT", "id": "D4A828-1", "name": "Polycystin-2-like protein 2", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSEATWWHRGGTSKHDLHYRREAEVNTTLEELLLYFIFLINLCILTFG--------------------TVNPHMYYLNKVMSSLFVDTSLPDDERSS-----------------------FRSIRSITEFWKF----------------------------------MEGPLVEGLYWDSWYGNTQLDSVK-----------------NSSLIYY--------------------------ENILLGVPRVRQLRVRNSTCQVY-PAFQSLASDCYNKYTAENEDFSDFGLKHDPEWRHSAP-------SSTAPWHWGFVGVYRD-GGYMVTLSKSKSETKAKLADLRQNNWIGRGTRAVFIDFSLYNANVNLFCIIRLLAEFPATGGILTSWQFYSVKLIRYVSYYDHFIASCEIIFCIFLLVFITQELRKLN-EFKSAYFRSVWNWIELLLLVLCFLAVSFYAYCN-VQCFLLLGQLLRSTESYPDFYFLAYWHIYYNNIIAITIFFAWIKIFKFISFNETMSQLSSTLSRCMKDIVGFAIMFFIIFFAYAQLAFLVFGSQVDDFSTFQNSIFAQFRIVLGDFNFAG---IQQANWILGPIYFITFIFFVFFVLLNMFLAIINDTYSEVKADYSIGRRPDFELGSIIKKSCFNILEKLRLRKAQNNEDKKMKTS-VDLAQARKEGFDESEIQEARQMKRWKERLEKKYYSTEIQDDYQPVTQQEFRELFLYAVELEKELHYLSLK--------------------LNQVMRKLH---------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9JLG4-1", "uniprot_id": "PK2L2_MOUSE", "id": "Q9JLG4-1", "name": "Polycystin-2-like protein 2", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSEATWWYRGGTSKHDLHYRREAEVNTTLEELLLYFIFLINLCILTFG--------------------MVNPHMYYLNKVMSSLFVDTSLPDDERSS-----------------------FRSIRSITEFWKF----------------------------------MEGPLIDGLYWDSWYGNKQLYSVK-----------------NSSRIYY--------------------------ENVLLGIPRVRQLRVRNNTCKVY-PAFQSLVSDCYSKYTVENEDFSDFGLKRNPEWTHTPS-------SRTAPWHWGFVGVYRD-GGYIVTLSKSKSETKAKFVDLRLNNWISRGTRAVFIDFSLYNANVNLFCIIRLLAEFPATGGLLTSWQFYSVKLLRYVSYYDYFIASCEVIFCIFLFVFIIQELRKVN-EFKSAYFRSVWNWLEMLLLLLCFLAVSFYAYCN-MQSFLLLGQLLKNTDSYPDFYFLAYWHIYYNNVIAITIFFAWIKIFKFISFNETMSQLSSTLSRCMKDIVGFAIMFFIIFSAYAQLGFLVFGSQVDDFSTFQNSIFAQFRIVLGDFNFAG---IQQANWILGPIYFITFIFFVFFVLLNMFLAIINDTYSEVKADYSIGRRPDFELGKIIQKSCFNVLEKLRLKKAQAKEEKKMQTT-DLAQRARRDGFDESEIQEAEQMKRWKERLEKKYYSTEIQDDYQPVTQQEFRELFLYAVELEKELHYVSLK--------------------LNQLMRKLH---------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9NZM6-1", "uniprot_id": "PK2L2_HUMAN", "id": "Q9NZM6-1", "name": "Polycystin-2-like protein 2", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MAEASRWHRGGASKHKLHYRKEVEITTTLQELLLYFIFLINLCILTFG--------------------MVNPHMYYLNKVMSSLFLDTSVPGEERTN-----------------------FKSIRSITDFWKF----------------------------------MEGPLLEGLYWDSWYNNQQLYNLK-----------------NSSRIYY--------------------------ENILLGVPRVRQLKVRNNTCKVY-SSFQSLMSECYGKYTSANEDLSNFGLQINTEWRYSTS-------NTNSPWHWGFLGVYRN-GGYIFTLSKSKSETKNKFIDLRLNSWITRGTRVIFIDFSLYNANVNLFCIIRLVAEFPATGGILTSWQFYSVKLLRYVSYYDYFIASCEITFCIFLFVFTTQEVKKIK-EFKSAYFKSIWNWLELLLLLLCFVAVSFNTYYN-VQIFLLLGQLLKSTEKYSDFYFLACWHIYYNNIIAITIFFAWIKIFKFISFNKTMSQLSSTLSRCVKDIVGFAIMFFIIFFAYAQLGFLVFGSQVDDFSTFQNSIFAQFRIVLGDFNFAG---IQQANPILGPIYFITFIFFVFFVLLNMFLAIINDTYSEVKADYSIGRRLDFELGKMIKQSYKNVLEKFRLKKAQKDEDKKTKGSGDLAEQARREGFDENEIQNAEQMKKWKERLEKKYYSMEIQDDYQPVTQEEFRELFLYAVELEKELHYINLK--------------------LNQVVRKVSAL-------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VVZ8-1", "uniprot_id": "Q9VVZ8_DROME", "id": "Q9VVZ8-1", "name": "", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MAKKFSNIIFYLTLIIIAICVACIWMFSGFRHEYGKFNMILVAFLAVTLLQILIFTPIKFTIMSLDAAFWP--AHQAPETP-DENANVDTFMDNLRLRLRTLRSELMITERHRNERVNLKYRLITEELWLTGKLFLVYFFMALAFFDELLY----------------------------------FNTEATELLFQCNHGDAFGLLSVG-----------------DVPDIYFFVVSSLVLAFTDGKNTSGGAPWIHAEGTRLLGVVRLRQLRTESNRLGLSLPVFTERDFSESWTLPYERVPYTDKYWPIYTPWLPSVS--VARDNLLMGINHVGHMFNYPESKGYKVLLSDTRHKSLKIIDYLMKKNWLDANTTALFMDFSLYNADANTFTVCTLWVEKFPYQYPDGHTRIESHTFVEQLREFTKFGMLMVFVFVVTWLQFTKAFFLKV--WYDPRQLKTLWVQVDAMIVALSLVVGMIMSVRDNLVQKMIKSVEIAVVVDFLDFREPAQLAYLEDVVTGLAVALVTMRLWKVLQFSATFQLFTKTIAMAWDALLCTFVITVIFIIAIGIATVTINGNYTSNFRDFPKGIVTVTCFAFGYTNLVYPPDIFYGGEWLGILLYTIMGFVVKYMLINLIVSMMRDQMASVKADRDKKVRQRITFWQFLRVEYAHFINYIVKVFHCQKGYQRKNRTVAQNIQRKLNSNELKRRKTKISSIYSETIYVMPIDKDLEQMKYRERIERTFTLAAILHTQMELMERLMFGD------EEGNLP-------SLDQEDEQVPETEED----", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "X2JI61-1", "uniprot_id": "X2JI61_DROME", "id": "X2JI61-1", "name": "", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MKVKKTHWAMFAITVGIIIGCMICIAVFAGFQHEDVKFKTMLVSIVIVLIFQFLIGDPIKFVILSIDRALWPPRIYIPPRCDKDEMDEKEERRDFLKQRLINKRANLMLTSRYRNYKLNDQYKMIAHDLFIYGPYFLCLMCLVLVTRDQTLY----------------------------------HNTRIITDLFMYNHTDYTGLQEVY-----------------FLNQLFDFIESTLVLAFNSNSTESGSPGWAHAEQSVLLGVMRLRQLRVSNPQVGLGPPKFSDTYYMPDWQLPYRKLHYSDKYWRIYEPWIPIKMGFEFLDALLMNFDHVGSLNSYPELAGYVSLLARSAANSMKVIDYLSENHWLTLNTSAVFIDFTLYNVDVNLFSICTLRVEKTPFGGIVPDVQVDSAKLLENVDQMPYTGLLALLIYVLVFIQFAQTLAVKL--WYEPHLLKSVWNKLDLFIFMVNVLVVVLVVLRESLVASMMKKVEGASKMEFIDFRRPSRMHQLTTITIGFLICITTLRLWRVLQFASVFKLFTRTLYLAWSAVASTAIAIVIFLIGFCFAVVTINGNYSSNFNKLVKSMVMCMCYSFGFSAQVKPSELFHGGKWLGILCYGVLAFVIIVLLINVFVSLINDYFTVAKTIRDSERENRITFFEFLVVEFSGVLGRFRKLPCWRRNYVRNGRTVAENVSRKLDSMDRQR-LMRRRLRQGRHHVSRPVSAEDALLEYKDRGDKMVNVHYILNIQLTLIRMFLFDEYVEWPQEQQKQPEAQDPDPNLGPDGSPPQDKRQDEAEA", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VK95-1", "uniprot_id": "Q9VK95_DROME", "id": "Q9VK95-1", "name": "", "aln": "MAQQGQSGRSPSGPPGPPPPRPPKTPPGASPRGTPTADSTPGDVTPARGPPPPPATKRVSIGVGSTRSAPPPATDPTGPPPTAGKPVRDTGPSTSPRPSLRDPGQSTSDKPSTSDKPSTSDKPSTSARTTVREPGPSSSPSRPVSTRESGRITFQEAAPSTSAKVVKLAASEPRPAKPPEKEGFSLFKRKKKSVGSSTPPSPSRGHRAPSIIAASALQNRAKTNRILYTTDEEVREALVEFSVFIIFLILTSLVVLS--------------------VRHTYMFYFNDTMKKLFTNREMVVAPSVTVGFEKLITVPDWWDYLKYNFLVTLHGDLTFMDDAQANLTSMPPEGSEQGSEQGSEQGSEQSPEEVVGEAPEEAPEMDRLQEDFKYNGNPYIDLRGHRRAKRQSGVDGNSEDGSEDVSGNYLKDDSDSIQANMSFHHLEGRVFLYENLLLGPPRLRQIRVRKESCYVN-DAFIRYFNTCYAAYSSGAEDR--KPMHKGSPFRTMHD--------LDSTPIWTVLAFYRT-GGYTVNLDYDKDRNVKIINDLKDIHWLDRGSRLCLVEFNLFNENTDIFQSIKLIAEIPPTGGVIPQAHLQTVKMYSFFTDRSMLMTVIYIFWYIMVIYYTIYEITEIRKSGIKIYFCSMLNILDCAILLGCYLALVYNIWHS--FKVMSLTARAHSDVTYQSLDVLCFWNIIYVDMMAILAFLVWIKIFKFISFNKTLVQFTTTLKRCSKDLAGFSLMFGIVFLAYAQLGLLLFGTKHPDFRNFITSILTMIRMILGDFQYNL---IEQANRVLGPIYFLTYILLVFFILLNMFLAIIMETYNTVKGEITQGRS---HLGSYIYRKLSGMLYWITHCGRKRRHHPQASETEDKDAEHDVGAAHDETHEIRKNMTPAEQQYFKDIPQGENQDMVRLN-----NRVGLLEEILEKLINNMDDI--------------------LKRVEKDYHNKKK-----", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . : : : . : * :: :. . :. : . : : : : : * . .: : . *** *:**::. . : * . : : * ** * .. : * *: .: :::*.*:* :.: * * .* . :. : .: . . : : : : :: : :: :: :. :. . : : .: . .: :. :::::.:.* .: :: *: . . : : *.: . . : *. :* : ..:. :* : .. ** : : :.: :*:*:::::: : .* : . : . .: : : : . . . . : : : : * ", "identical_positions": 33, "similar_positions": 147, "identity": "3.32%" }, { "cls_id": "homologset.agr.MGI:1858232", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q6AY63-1", "uniprot_id": "NUDT5_RAT", "id": "Q6AY63-1", "name": "ADP-sugar pyrophosphatase", "aln": "----------------METQEPKDSSPPTEQRILS--EELISEGKWVKFEKTTYMDPTGKTRTWETVKLTTRKGKSADAVSVIPVLQR-TLHHECIVLVKQFRPPMGGYCLEFPAGLIEDGESPEAAALRELEEETGYKGDIAECSPAVCMDPGLSNCTTHVVTVTINGDDAGNVRPKPKPGDGEFVEVISLPKNDLLTRLDALGAEDRLTVDARVYAYALALKHANAKPFEVPFLKF", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9JKX6-1", "uniprot_id": "NUDT5_MOUSE", "id": "Q9JKX6-1", "name": "ADP-sugar pyrophosphatase", "aln": "----------------METRESTESSP-GKHLVTS--EELISEGKWVKFEKTTYMDPTGKTRTWETVKLTTRKGKSADAVSVIPVLQR-TLHHECVILVKQFRPPMGSYCLEFPAGFIEDGESPEAAALRELEEETGYKGEVAECSPAVCMDPGLSNCTTHVVTVTINGDDAGNVRPKPKPGDGEFMEVISLPKNDLLTRLDALGAEQHLTVDAKVYAYGLALKHANSKPFEVPFLKF", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9UKK9-1", "uniprot_id": "NUDT5_HUMAN", "id": "Q9UKK9-1", "name": "ADP-sugar pyrophosphatase", "aln": "----------------MESQEPTESSQNGKQYIIS--EELISEGKWVKLEKTTYMDPTGKTRTWESVKRTTRKEQTADGVAVIPVLQR-TLHYECIVLVKQFRPPMGGYCIEFPAGLIDDGETPEAAALRELEEETGYKGDIAECSPAVCMDPGLSNCTIHIVTVTINGDDAENARPKPKPGDGEFVEVISLPKNDLLQRLDALVAEEHLTVDARVYSYALALKHANAKPFEVPFLKF", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q01976-1", "uniprot_id": "ADPP_YEAST", "id": "Q01976-1", "name": "ADP-ribose pyrophosphatase", "aln": "MFLRNVRVISLNSRRLFRTMSTVKGKPEDAKIIEARHVKETSDCKWIGLQKIIYKDPNGKEREWDSAVRTTRSSGGVDGIGILTILKYKDGKPDEILLQKQFRPPVEGVCIEMPAGLIDAGEDIDTAALRELKEETGYSGKIISKSPTVFNDPGFTNTNLCLVTVEVDMSLPENQKPVTQLEDNEFIECFSVELHKFPDEMVKLDQQG-YKLDARVQNVAQGILMAKQYHIK------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :.: .. ... : : : : *: **: ::* * **.** * *::. ***. .*.:.::.:*: : : ::* ******: . *:*:***:*: ** ::******:*****.*.: . **:* ***::* . :*** :: . . * :* .: *.**:* :*: :.: .: * : .:**:* . .: *: :: ", "identical_positions": 65, "similar_positions": 78, "identity": "27.31%" }, { "cls_id": "homologset.agr.MGI:1858233", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0ABK0LIM9-1", "uniprot_id": "A0ABK0LIM9_RAT", "id": "A0ABK0LIM9-1", "name": "Nephrocystin-1", "aln": "MLARRPRDPLQALRRRGQELKLQVDSLVTESQLTGALEPSKRRDIYQRCIQLKQAVDENKNALQKLNKADEAAPVGNYEQRKEEEHTLLEKLACQLQELAVGISRKDTLKVEAHSDKEEDDTTEDDEEETEETGGEEEESEGDEEGKQEQASP--EHAETVTYIALGDFAAQQAGDLTFKKGDILHIIEKRPDGWWLAKDAEGGEGLIPRTYLEPYNKEDKLESSEGSEEGDEEGVGEDGEDGEDGEDGEEDVEVVDETADGAQVKQRTDSHWSAVRKAISE--------------------------------------------------------INTVDVLATMGAIPAGFRPSTLSQLLDEGKAPYSIWLDLLARKPQGSPASVPQHWDTGGRFRASYFLQPELTTSQLAFRDLTWDAKTGTIMSRPSRVSLILTLWSCKMIPLPGTSIQVLSRHIRLCLFDGSKVLSNIHTVRAVWQPKKPKTWTFSPQVTGILPCLLDGDCFIRSNSSTPDLGILFELGISYIRNSTGERGELSCGWVFLKLFDASGVPIPAKTYELFLNGGTPYEKGVEVDPSVSRRAQGSVFRQMISVRRQPQLLVKLRSLNRRSRAMLSLLPETLVGSMCSAHLLIFYRQILGDVLLRDRTSLQSADLISHPVLATFPLLLEQPDVMDALRSSWAEKESTLKRSEKRDKELLKAEFLLVYHDCVLPLLHSTLLPPFRWAEEETEAARWKAIADFLKQSRENEGSLKALLSPDGVHKPFDLSEQTYDFLGEIRKNSG", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9QY53-1", "uniprot_id": "NPHP1_MOUSE", "id": "Q9QY53-1", "name": "Nephrocystin-1", "aln": "MLARRPRDPLQALRRRGQELKLQVDSLVTESQLTGALEPSKRREIYQRCIQLKQAVDENKNTLQKLNKADEAAPVGNYEQRKEEEHSLLEKLACQLQELAVSISRKDALKVEAHSDKEEDDTTEDDE---EETGGEEEESEGDGEGKQEQASPKQAETETVTYIALGDFAAQQTGDLTFKKGDVLHIIEKKPDGWWLAKDAEGVEGLIPRTYLEPYNKEDKLESSEGSEEGGEE-------------DGEEDVEVVDETADGAQVKQRTDSHWSAVRKAISEQ-------------------------------------------------------INTVDVLATMGAIPAGFRPSTLSQLLDEA----------------------------GNQFRASYFLQPELTTSQLAFRDLTWDAKAGTIMSRPSRVSLILTLWSCKMIPLPGTSIQVLSRHIRLCLFDGSKVLSNIHTVRAVWQPKKPKTWTFSPQVTGILPCLLDGDCFIRSNSSTPDLGILFELGISYIRNSTGERGELSCGWVFLKLFDASGVPIPAKTYELFLNGGTPYEKGVEVDPSVSRRAQGSVFRQMISVRRQPQLLVKLRSLNRRSRAMLSLLPETLVGSMCSAHLLIFYRQILGDVLLRDRTNLQSADLISHPVLATFPLLLEQPDVMDALRSSWSEKESTLKRAEKRDKELLKAEFLLVYHDCVLPLLHSTLLPPFRWAEEETEAARWKAIADFLKQSRENEGSLKALLSPDGVHKPFDLSEQTFDFLGEIRKNSG", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O15259-1", "uniprot_id": "NPHP1_HUMAN", "id": "O15259-1", "name": "Nephrocystin-1", "aln": "MLARRQRDPLQALRRRNQELKQQVDSLLSESQLKEALEPNKRQHIYQRCIQLKQAIDENKNALQKLSKADESAPVANYNQRKEEEHTLLDKLTQQLQGLAVTISRENITEVGAPTEEEEESESEDSE----DSGGEEEDAEEEEEEKEENESH--KWSTGEEYIAVGDFTAQQVGDLTFKKGEILLVIEKKPDGWWIAKDAKGNEGLVPRTYLEPYSEEE--EGQESSEEGSEE-----------------DVEAVDETADGAEVKQRTDPHWSAVQKAISEAGIFCLVNHVSFCYLIVLMRNRMETVEDTNGSETGFRAWNVQSRGRIFLVSKPVLQINTVDVLTTMGAIPAGFRPSTLSQLLEEG-----------------------------NQFRANYFLQPELMPSQLAFRDLMWDATEGTIRSRPSRISLILTLWSCKMIPLPGMSIQVLSRHVRLCLFDGNKVLSNIHTVRATWQPKKPKTWTFSPQVTRILPCLLDGDCFIRSNSASPDLGILFELGISYIRNSTGERGELSCGWVFLKLFDASGVPIPAKTYELFLNGGTPYEKGIEVDPSISRRAHGSVFYQIMTMRRQPQLLVKLRSLNRRSRNVLSLLPETLIGNMCSIHLLIFYRQILGDVLLKDRMSLQSTDLISHPMLATFPMLLEQPDVMDALRSSWAGKESTLKRSEKRDKEFLKSTFLLVYHDCVLPLLHSTRLPPFRWAEEETETARWKVITDFLKQNQENQGALQALLSPDGVHEPFDLSEQTYDFLGEMRKNAV", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "***** **********.**** *****::****. ****.**:.***********:*****:****.****:***.**:*******:**:**: *** *** ***:: :* * :::**:. :**.* ::*****::* : * *:*: * : ***:***:***.********::* :***:*****:****:* ***:********.:*: *..*.****.** ***.********:******.*****:***** *******:******************:*. .:***.******* .******** ***. *** *****:**************** ********:*******.***********.**************** ****************::***********************************************************:*****:****:**** *::::****************** :********:*.*** ***************:** .***:******:*****:***************: *******:******:**: **************** ************:****.*:*****.:**:*:*:*********:********:*****:***: ", "identical_positions": 538, "similar_positions": 100, "identity": "68.45%" }, { "cls_id": "homologset.agr.MGI:1858234", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q5M9G3-1", "uniprot_id": "CAPR1_RAT", "id": "Q5M9G3-1", "name": "Caprin-1", "aln": "---------------------------------------------MP----------SATSHSGSGSKSSGPPPPSGSSGSEAAAGA--AAPASQHPATGTGAVQTEAMKQILGVIDKKLRNLEKKKGKLDDYQERMNKGERLNQDQLDAVSKYQEVTNNLEFAKELQRSFMALSQDIQKTIKKTARREQLMREEAEQKRLKTVLELQYVLDKLGDDDVRTDLKQGLSGVPILSEEELSLLDEFYKLVD---PERDMSLRLNEQYEHASIHLWDLLEGKEKPVCGTTYKALKEIVERVFQSNYFDS---THNHQNGLCEEEEAASAP-IVEDQ------------VAEAEPEP----------------TEEYTEQSEVESTEYVNRQFMAETQFSSGEKEQVDEW--AVETVEVVNSLQQ--------------QPQAASPSVP--EPHSLTP------VAQ----SDPLVRRQ------------------------------------RVQDLMAQMQ--------GPYNFIQDSMLDFENQTLDP------AIVSAQPMNPTQNMDMPQLVCPQVHSESRLAQSNQVPVQPEA----------------TQVPLVSSTSEGYTASQPLYQPSHAAEQ--------------------------RPQKEPIDQIQATISLNTEQTTASSSLPAASQPQVFQAGASKPLHSSGINVNAAPFQSMQTVFN-----MNAPVPP------VNEPETLKQQSQYQASYNQSFSSQPHQ-VEQTELQQDQLQTVVGTYHGSQDQPHQVPGNHQQPPQQ----STGFPRSSQPYYN--SRGVSRGGSRGARGLMNGYRGPANG---FRGGYDGYRSSFSNTPNSGYTQSQFNAPRDYSG---------YQRDGYQQNFKRGSGQSGPRGAPRGRGGPPRPNRGMPQMNTQQVN------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q60865-1", "uniprot_id": "CAPR1_MOUSE", "id": "Q60865-1", "name": "Caprin-1", "aln": "---------------------------------------------MP----------SATSHSGSGSKSSGPPPPSGSSGSEAAAGA--AAPASQHPATGTGAVQTEAMKQILGVIDKKLRNLEKKKGKLDDYQERMNKGERLNQDQLDAVSKYQEVTNNLEFAKELQRSFMALSQDIQKTIKKTARREQLMREEAEQKRLKTVLELQYVLDKLGDDDVRTDLKQGLSGVPILSEEELSLLDEFYKLVD---PERDMSLRLNEQYEHASIHLWDLLEGKEKPVCGTTYKALKEIVERVFQSNYFDS---THNHQNGLCEEEEAASAP-TVEDQ------------VAEAEPEP----------------AEEYTEQSEVESTEYVNRQFMAETQFSSGEKEQVDEW--TVETVEVVNSLQQ--------------QPQAASPSVP--EPHSLTP------VAQ----SDPLVRRQ------------------------------------RVQDLMAQMQ--------GPYNFIQDSMLDFENQTLDP------AIVSAQPMNPTQNMDMPQLVCPQVHSESRLAQSNQVPVQPEA----------------TQVPLVSSTSEGYTASQPLYQPSHATEQ--------------------------RPQKEPMDQIQATISLNTDQTTASSSLPAASQPQVFQAGTSKPLHSSGINVNAAPFQSMQTVFN-----MNAPVPP------ANEPETLKQQSQYQATYNQSFSSQPHQ-VEQTELQQDQLQTVVGTYHGSQDQPHQVPGNHQQPPQQ----NTGFPRSSQPYYN--SRGVSRGGSRGARGLMNGYRGPANG---FRGGYDGYRPSFSNTPNSGYSQSQFTAPRDYSG---------YQRDGYQQNFKRGSGQSGPRGAPRGRGGPPRPNRGMPQMNTQQVN------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q14444-1", "uniprot_id": "CAPR1_HUMAN", "id": "Q14444-1", "name": "Caprin-1", "aln": "---------------------------------------------MP----------SATSHSGSGSKSSGPPPPSGSSGSEAAAGAGAAAPASQHPATGTGAVQTEAMKQILGVIDKKLRNLEKKKGKLDDYQERMNKGERLNQDQLDAVSKYQEVTNNLEFAKELQRSFMALSQDIQKTIKKTARREQLMREEAEQKRLKTVLELQYVLDKLGDDEVRTDLKQGLNGVPILSEEELSLLDEFYKLVD---PERDMSLRLNEQYEHASIHLWDLLEGKEKPVCGTTYKVLKEIVERVFQSNYFDS---THNHQNGLCEEEEAASAP-AVEDQ------------VPEAEPEP----------------AEEYTEQSEVESTEYVNRQFMAETQFTSGEKEQVDEW--TVETVEVVNSLQQ--------------QPQAASPSVP--EPHSLTP------VAQ----ADPLVRRQ------------------------------------RVQDLMAQMQ--------GPYNFIQDSMLDFENQTLDP------AIVSAQPMNPTQNMDMPQLVCPPVHSESRLAQPNQVPVQPEA----------------TQVPLVSSTSEGYTASQPLYQPSHATEQ--------------------------RPQKEPIDQIQATISLNTDQTTASSSLPAASQPQVFQAGTSKPLHSSGINVNAAPFQSMQTVFN-----MNAPVPP------VNEPETLKQQNQYQASYNQSFSSQPHQ-VEQTELQQEQLQTVVGTYHGSPDQSHQVTGNHQQPPQQ----NTGFPRSNQPYYN--SRGVSRGGSRGARGLMNGYRGPANG---FRGGYDGYRPSFSNTPNSGYTQSQFSAPRDYSG---------YQRDGYQQNFKRGSGQSGPRGAPRGRGGPPRPNRGMPQMNTQQVN------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0ACD6B5T4-1", "uniprot_id": "A0ACD6B5T4_DANRE", "id": "A0ACD6B5T4-1", "name": "", "aln": "---------------------------------------------MP----------SVTAG-DNAVHSSSP---------------------------DLGSAPSEALKQVLVVIDKKVRNMEKRKSKLDDYQTRKDKGERLNQDQLEALSKAPEVAHNLDFARELQKSFLALNVEIQKTVKKATRREQLKREEAERKRLKAVLEIQYLLEQLGEENVRQELTQSTGEASLLTEAELMGLDEFYKLIG---PERDSSVRLAEQFDEASVHLWELLEGRDKAVAGTTYKALKETLDKMLLSGYFDR---APTHQNGVCEEETGATVVESSESE------------EHPAEPEG----------------AAQEYSETEVEATEFVNRQFIPEAAYSSSEKEQGAEWNTSSQVVSVLQQPQQ--------------PPAAMSPTLMSSEAHTLNA------VLPPPPATDPVVRKQ------------------------------------AVQDLMAQMQ--------GTFNFMQDSMLEFEGPPLDP------AIVSAQPMKP------AQMVCP---PESRLPQHNALSVQPEP----------------TQVPMVSASTP------PLYQPAHTSEP--------------------------RPQTDTIDPLQVSMPLPSEQPPTPS-----SQPQVFQP---KPLHS-GINVNAAPFQSMQAVFN-----MNAPVPP------TNEMDSPKISSQYQSSYGQGFSTQAALPAEQQEMPQEALQS-VGSFQ-SQDQGITSAGGHQSAPQQPSGQGTGFGRPGQSFYS--NRAMPRTGPRNPRGSLNGYRGPSNG---FRGGYDGYRAPFPNTPNTGYGQTQFSTPRDYSNN-------TYQREGYQQSFKRGAAQ-GPRGCSRGRGGSYRSSRGMVPMAAQQTS------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9I7D3-1", "uniprot_id": "CAPR1_DROME", "id": "Q9I7D3-1", "name": "Caprin homolog", "aln": "MPSAANTATVTAAIATTVAASASNTNNNSVSKEKRSSIISLGGSVIPGTAVAAGAGVATTNGQSNSSAAATADGSQTDLASSNNNGNAAKSKANAVSAAAVVPEPYNPLKQLLVTIEHKIRNLEKRKTKLESYRAIQSSGKELSGDQASAVAKYDAVLANLEFARELAKHIQQQSKEAEKEQKKQARKDNLAKTIAETAKIREVLIIQNVLNCFNDDQVRSDFLNGENGAKKLENTELELLEKFFIETQTRRPETADDVSFIATAQKSAELFYSTINARPKSFGEVSFEKLRSLFQQIQDSGYLDKYYLVPLAENAVANSTDSGTGSGDGESGDLLNDGSGELDAELPSEPSARNSLEEGLDKLHLGVQAELDQHQSYQQQQERPSHLLEPQHQRAPSLEHQQNSMVQQVSTQVYQAAPQAGGTTTPVHVLYAPAPPAQQQPQQPPPHPHQLLSSPVNLQALQTGTAAPPAQQQQPHPTHFAPNVRAVEQNYFKQPPQHPQGPGIQAPQTPQQQQFMQHSRPLAEVLGTGRFHFLQDSELDNPEALAPPPPTNQGLVFEQQPQQPNHVEEPTQAILTLTFTNQSFPSQQPQPQQQGPQQQQQLFSPVLIHEQRQQPPQQQPQPMLIMPRLPTQQPQQPAPQGIGMQAGDVTSGFSYENAVVSYEQQIQQQLKQQQQQQQQQQQNLQQLDEPSSVNSSSSVGAGGDVENNEWHARNNDTNAAATAALTNVLKGETTQATPPAPPTKWSSEMNAMSSAASNGSSNTSHKQEWATPRDHSTGGGNSGYADNNESNNHWNNSQGDGRRNSGNYQRRGGDRDNRDRDQGGRGDERRNGGDRGNYRSRQYGNSSNTNGRNSGNSSGVYFRNNESGNGGGNNYYQNGGGGGGTYNKESRYESSGGGGGSYRGQRGGNQQRNVNGSYGGGRPMGDRGRGGAGNQGGGGGGYINRQNQSQRMPLGLENKN", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :* :.* ... :: . . :.:**:* .*::*:**:**:* **:.*: ..*:.*. ** .*::* * **:**:** : : . : :* ** :*:::* : ** ::: ** :* :*: :.:::** :: :. . . * : ** *::*: ** .: : :.:: ::. ::.: *.. .::: *:. .::: *.*:* . :*.:.:. ..: *. :**. : :: : * .: : .: :.. :.* . .. * * .* ..* * . . : * ::* *::* : : * ::*:*** *: * :.. ** :* .* : . .:. :.. : . * . * * .. . * ** :.: : * . : * :* .* *. . : *: . :.***. :: *:: ..*.** * .: ... :::: * ::: . : : . :: * .: .*.:* : . . .: . .*. * . . ** .. .. **.. .* * * :. *.. ** * ** .*: * *****. . . * :* . ", "identical_positions": 127, "similar_positions": 231, "identity": "13.22%" }, { "cls_id": "homologset.agr.MGI:1858235", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9QYP2-1", "uniprot_id": "CELR2_RAT", "id": "Q9QYP2-1", "name": "Cadherin EGF LAG seven-pass G-type receptor 2", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------EDQVSYTLAITARDNGIPQKSDTTYLEILVNDVNDNAPQFLRDSYQGSVYEDVPPFTSVLQISATDRDSGLNGRVFYTFQGGDDGDGDFIVESTSGIVRTLRRLDRENVAQYILRAYAVDKGMPPARTPMEVTVTVLDVNDNPPVFEQDEFDVFVEENSPIGLAVARVTATDPDEGTNAQIMYQIVEGNIPEVFQLDIFSG----ELTALVDLDYE-DRPEYILVIQATSAPLVSRATVHVRLLDRNDNPPVLGNFEILFNNYVTNRSSSFPGGAIGRVPAHDPDISDSLTYSFERGNELSLVLLNASTGELRLSRALDNNRPLEAIMSVLVSDGVHSVTAQCSLRVTIITDEMLTHSITLRLEDMSPERFLSPLLGLFIQAVAATLATPPDHVVVFNVQRDTDAPGGHILNVSLSVGQPPGPGGGPPFLPSEDLQERLYLNRSLLTAISAQRVLPFDDNICLREPCENYMRCVSVLRFDSSAPFIASSSVLFRPIHPVGGLRCRCPPGFTG----DYCETEVDLCYSRPCGPHGHCRSREGGYTCLCRDGYTGEHCEVSARSGR-CTPGVCKNGGTCVNLLVGGFKCDCPSGDFEKPFCQVTTRSFPARSFITFRGLRQRFHFTLALSFATKERDGLLLYNGRFNEKHDFVALEVIQEQVQLTFSAGESTTTVSPFVPGGVSDGQWHTVQLKYYNKPLLGQTGLPQGPSEQKVAVVSVDGCDTGVALRFGAMLGNYSCAAQGTQGGSKKSLDLTGPLLLGGVPDLPESFPVRMRHFVGCMKNLQVDSRHVDMADFIANNGTVPGCPTKKNVCDSNTCHNGGTCVNQWDAFSCECPLGFGGKSCAQEMANPQRFLGSSLVAWHGLSLPISQPWHLSLMFRTRQADGVLLQAVTRGRSTITLQLRAGHVVLSVEGTGLQASSLRLEPGRANDGDWHHAQLSLGASGGPGHAILSFDYGQQKAEGNLGPRLHGLHLSNMTVGGVPGPASSVARG--FRGCLQGVRVSETPEGVSSLDPSRGESINVEPGCSWPDPCDSNPCPTNSYCSNDWDSYSCSCDPGYYGDNCTNVCDLNPCEHQSACTRKPSAPHGYICECLPN-YLGPYCETRIDQPCPRGWWGHPTCGPCNCDVSKGFDPDCNKTSGECHCKENHYRPPSSPTCLLCDCYPTGSLSRVCDPEDGQCPCKPGVIGRQCDRCDNPFAEVTTNGCEVNYDSCPRAIEAGIWWPRTRFGLPAAAPCPKGSFGTAVRHCDEHRG-WLPPNLFNCTSVTFSELKGFAERLQRNESGLDSGRSQRLALLLRNATQHTSG-----------------------------------------------------YFGSDVKVAYQLATRLLAHESAQRGFGLSATQDVHFTENLLRVGSALLDAANKRHWELIQQTEG-GTAWLLQHYEAYASALAQNMRHTYLSPFTIVTPNIVISVVRLDKGNFAG---TKLPRYEALRGERP-----------------------------PDLETTVILPESVFREMPPMVRSAGPGEAQETEELARRQRRHPELSQGEAVASVIIYHTLAGLLPHNYDP------------------------------DKRSLRVPKRPVIN--TPVVSISVHDDEELLPRALDKPVT----------------------------------------------------------------------------------------------------------------------VQFRLLETEERTKPICVFWNHSILVSGTG---------------GWSARGCEVVFRNES-----------HVSCQCNHMTSFAVLMDVSRRENGE--ILPLKTLTYVALGVTLAALMITFLFLTLLRALRSNQHGIRRNLTAALGLAQLVFLLGIN----QADLPFACTVIAILLHFLYLCTFSWALLEALHLYRALTEVRDVNASPMRFYYMLGWGVPAFITGLAVGLDPEGYGNPDFCWLSIYDTLIWSFAGPVAFAVSMSVFLYILSARASCAAQRQGFEKKGPVSGLRSSFTVLLLLSATWLLALLSVNSDTLLFHYLFAACNCVQGPFIFLSYVVLSKEVRKALKFACSRKPSPDPALTTKSTLTS-------------------------------SYNCPSPYADGRLYQPYGDSAGSLHSASRSGKSQPSYIPFLLREESTLNPGQVPPGLGDPS---------GLFMEGQAQQHDPDTDSDSDLSLEDDQSGSYASTHSSDS---------------------------------------------EEEEEE----AAFPGEQGWDSLLGPGAERLPLHSTPK------------------------------------------------------------------DGGPGSGKVPWPGDFGTTTKENSGSGPLEERPRENGDALTREGS-----------------------LGPLPGPSTQPHKGILKKKCLPTISEKSSLLRLPLEQGTGSSRG------------------STASEGSRNGPPPRPPPRQSLQEQLNGVMPIAMSIKAGTVDEDSSGSEFLFFNFLH------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9R0M0-1", "uniprot_id": "CELR2_MOUSE", "id": "Q9R0M0-1", "name": "Cadherin EGF LAG seven-pass G-type receptor 2", "aln": "----------------------------------------------------------------------------------------------------MRSRAASAPLPTPLLPLLLLLLLLP----------PSPLLGDQVGPCRSLGSGGRSSSGACAPVGWLCPASASNLWLYTSRCRESGIELTGHLVPHHDGLRVWCPESGAHIPLPPSSEGCPWSCRLLGIGGHLSPQGTLTLPEEHPCLKAPRLR----------------CQSCKLAQAPG----------------------------------------------------LRAGEGSPEESLGGRRKRNVNTAPQFQPPSYQATVPENQPAGTSVASLRAIDPDEGEAGRLEYTMDALFDSRSNHFFSLDPITGVVTTAEELDRETKSTHVFRVTAQDHGMPRRSALATLTILVTDTNDHDPVFEQQEYKESLRENLEVGYEVLTVRATDGDAPPNANILYRLLEGAGGS------PSDAFEIDPRSGVIRTRGPVDREEVESYKLTVEASDQGRDPGPR-SSTAIVFLSVEDDNDNAPQFSEKRYVVQVREDVTPG---APVLRVTASDRDKGSNALVHYSIMSGNARGQFYLDAQTGALDVVSPLDYETTKEYTLRIRAQDGGRPPLSNVSGLVTVQVLDINDNAPIFVSTPFQATVLESVPLGYLVLHVQAIDADAGDNARLEYSLAGVGHDFPFTINNGTGWISVAAELDREEVDFYSFGVEARDHGTPALTASASVSVTILDVNDNNPTFTQPEYTVRLNEDAAVGTSVVTVSAVDRDAHSVITYQITSGNTRNRFSITSQSGGGLVSLALPLDYKLERQYVLAVTASDG-TRQDTAQIVVNVTDANTHRPVFQSSHYTVNVNEDRPAGTTVVLISATDEDTGENARITYFMEDSIP-------QFRIDADTGAVTTQAELDYEDQVSYTLAITARDNGIPQKSDTTYLEILVNDVNDNAPQFLRDSYQGSVYEDVPPFTSVLQISATDRDSGLNGRVFYTFQGGDDGDGDFIVESTSGIVRTLRRLDRENVAQYVLRAYAVDKGMPPARTPMEVTVTVLDVNDNPPVFEQDEFDVFVEENSPIGLAVARVTATDPDEGTNAQIMYQIVEGNIPEVFQLDIFSG----ELTALVDLDYE-DRPEYVLVIQATSAPLVSRATVHVRLLDRNDNPPVLGNFEILFNNYVTNRSSSFPGGAIGRVPAHDPDISDSLTYSFERGNELSLVLLNASTGELRLSRALDNNRPLEAIMSVLVSDGVHSVTAQCSLRVTIITDEMLTHSITLRLEDMSPERFLSPLLGLFIQAVAATLATPPDHVVVFNVQRDTDAPGGHILNVSLSVGQPPGPGGGPPFLPSEDLQERLYLNRSLLTAISAQRVLPFDDNICLREPCENYMRCVSVLRFDSSAPFIASSSVLFRPIHPVGGLRCRCPPGFTG----DYCETEVDLCYSRPCGPHGRCRSREGGYTCLCLDGYTGEHCEASTHSGR-CTPGVCKNGGTCVNLLVGGFKCDCPSGDFEKPFCQVTTRSFPARSFITFRGLRQRFHFTLALSFATKERNGLLLYNGRFNEKHDFVALEVIQEQVQLTFSAGESTTTVSPFVPGGVSDGQWHTVQLKYYNKPLLGQTGLPQGPSEQKVAVVSVDGCDTGVALRFGAMLGNYSCAAQGTQGGSKKSLDLTGPLLLGGVPDLPESFPVRMRHFVGCMKDLQVDSRHIDMADFIANNGTVPGCPTKKIVCDSSICHNGGTCVNQWNAFSCECPLGFGGKSCAQEMANPQRFLGSSLVAWHGLSLPISQPWHLSLMFRTRQADGVLLQAVTRGRSTITLQLRAGHVVLSVEGTGLQASSLRLEPGRANDGDWHHAQLALGASGGPGHAILSFDYGQQKAEGNLGPRLHGLHLSNITVGGVPGPASGVARG--FRGCLQGVRVSETPEGISSLDPSRGESINVEPGCSWPDPCDSNPCPTNSYCSNDWDSYSCSCVLGYYGDNCTNVCDLNPCEHQSVCTRKPNTPHGYICECLPN-YLGPYCETRIDQPCPRGWWGHPTCGPCNCDVSKGFDPDCNKTSGECHCKENHYRPPGSPTCLLCDCYPTGSLSRVCDPEDGQCPCKPGVIGRQCDRCDNPFAEVTTNGCEVNYDSCPRAIEAGIWWPRTRFGLPAAAPCPKGSFGTAVRHCDEHRG-WLPPNLFNCTSVTFSELKGFAERLQRNESGLDSGRSQRLALLLRNATQHTSG-----------------------------------------------------YFGSDVKVAYQLATRLLAHESAQRGFGLSATQDVHFTENLLRVGSALLDAANKRHWELIQQTEG-GTAWLLQHYEAYASALAQNMRHTYLSPFTIVTPNIVISVVRLDKGNFAG---TKLPRYEALRGERP-----------------------------PDLETTVILPESVFREMPSMVRSAGPGEAQETEELARRQRRHPELSQGEAVASVIIYHTLAGLLPHNYDP------------------------------DKRSLRVPKRPVIN--TPVVSISVHDDEELLPRALDKPVT----------------------------------------------------------------------------------------------------------------------VQFRLLETEERTKPICVFWNHSILVSGTG---------------GWSARGCEVVFRNES-----------HVSCQCNHMTSFAVLMDMSRRENGE--ILPLKTLTYVALGVTLAALMLTFLFLTLLRALRSNQHGIRRNLTAALGLAQLVFLLGIN----QADLPFACTVIAILLHFLYLCTFSWALLEALHLYRALTEVRDVNASPMRFYYMLGWGVPAFITGLAVGLDPEGYGNPDFCWLSVYDTLIWSFAGPVAFAVSMSVFLYILSARASCAAQRQGFEKKGPVSGLRSSFTVLLLLSATWLLALLSVNSDTLLFHYLFAACNCVQGPFIFLSYVVLSKEVRKALKFACSRKPSPDPALTTKSTLTS-------------------------------SYNCPSPYADGRLYQPYGDSAGSLHSASRSGKSQPSYIPFLLREESTLNPGQVPPGLGDPS---------GLFLEGQAQQHDPDTDSDSDLSLEDDQSGSYASTHSSDS---------------------------------------------EEEEEE----AAFPGEQGWDSLLGPGAERLPLHSTPK------------------------------------------------------------------DGGPGSGKVPWLGDFGTTTKENSGSGPLEERPRENGDALTREGS-----------------------LGPLPGPSTQPHKGILKKKCLPTISEKSSLLRLPLEQGTGSSRG------------------SSISEGSRHGPPPRPPPRQSLQEQLNGVMPVAMSIKAGTVDEDSSGSEFLFFNFLH------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9HCU4-1", "uniprot_id": "CELR2_HUMAN", "id": "Q9HCU4-1", "name": "Cadherin EGF LAG seven-pass G-type receptor 2", "aln": "----------------------------------------------------------------------------------------------------MRSPATGVPLPTPPPPLLLLLLLLL----------PPPLLGDQVGPCRSLGSRGRGSSGACAPMGWLCPSSASNLWLYTSRCRDAGTELTGHLVPHHDGLRVWCPESEAHIPLPPAPEGCPWSCRLLGIGGHLSPQGKLTLPEEHPCLKAPRLR----------------CQSCKLAQAPG----------------------------------------------------LRAGERSPEESLGGRRKRNVNTAPQFQPPSYQATVPENQPAGTPVASLRAIDPDEGEAGRLEYTMDALFDSRSNQFFSLDPVTGAVTTAEELDRETKSTHVFRVTAQDHGMPRRSALATLTILVTDTNDHDPVFEQQEYKESLRENLEVGYEVLTVRATDGDAPPNANILYRLLEGSGGS------PSEVFEIDPRSGVIRTRGPVDREEVESYQLTVEASDQGRDPGPR-STTAAVFLSVEDDNDNAPQFSEKRYVVQVREDVTPG---APVLRVTASDRDKGSNAVVHYSIMSGNARGQFYLDAQTGALDVVSPLDYETTKEYTLRVRAQDGGRPPLSNVSGLVTVQVLDINDNAPIFVSTPFQATVLESVPLGYLVLHVQAIDADAGDNARLEYRLAGVGHDFPFTINNGTGWISVAAELDREEVDFYSFGVEARDHGTPALTASASVSVTVLDVNDNNPTFTQPEYTVRLNEDAAVGTSVVTVSAVDRDAHSVITYQITSGNTRNRFSITSQSGGGLVSLALPLDYKLERQYVLAVTASDG-TRQDTAQIVVNVTDANTHRPVFQSSHYTVNVNEDRPAGTTVVLISATDEDTGENARITYFMEDSIP-------QFRIDADTGAVTTQAELDYEDQVSYTLAITARDNGIPQKSDTTYLEILVNDVNDNAPQFLRDSYQGSVYEDVPPFTSVLQISATDRDSGLNGRVFYTFQGGDDGDGDFIVESTSGIVRTLRRLDRENVAQYVLRAYAVDKGMPPARTPMEVTVTVLDVNDNPPVFEQDEFDVFVEENSPIGLAVARVTATDPDEGTNAQIMYQIVEGNIPEVFQLDIFSG----ELTALVDLDYE-DRPEYVLVIQATSAPLVSRATVHVRLLDRNDNPPVLGNFEILFNNYVTNRSSSFPGGAIGRVPAHDPDISDSLTYSFERGNELSLVLLNASTGELKLSRALDNNRPLEAIMSVLVSDGVHSVTAQCALRVTIITDEMLTHSITLRLEDMSPERFLSPLLGLFIQAVAATLATPPDHVVVFNVQRDTDAPGGHILNVSLSVGQPPGPGGGPPFLPSEDLQERLYLNRSLLTAISAQRVLPFDDNICLREPCENYMRCVSVLRFDSSAPFIASSSVLFRPIHPVGGLRCRCPPGFTG----DYCETEVDLCYSRPCGPHGRCRSREGGYTCLCRDGYTGEHCEVSARSGR-CTPGVCKNGGTCVNLLVGGFKCDCPSGDFEKPYCQVTTRSFPAHSFITFRGLRQRFHFTLALSFATKERDGLLLYNGRFNEKHDFVALEVIQEQVQLTFSAGESTTTVSPFVPGGVSDGQWHTVQLKYYNKPLLGQTGLPQGPSEQKVAVVTVDGCDTGVALRFGSVLGNYSCAAQGTQGGSKKSLDLTGPLLLGGVPDLPESFPVRMRQFVGCMRNLQVDSRHIDMADFIANNGTVPGCPAKKNVCDSNTCHNGGTCVNQWDAFSCECPLGFGGKSCAQEMANPQHFLGSSLVAWHGLSLPISQPWYLSLMFRTRQADGVLLQAITRGRSTITLQLREGHVMLSVEGTGLQASSLRLEPGRANDGDWHHAQLALGASGGPGHAILSFDYGQQRAEGNLGPRLHGLHLSNITVGGIPGPAGGVARG--FRGCLQGVRVSDTPEGVNSLDPSHGESINVEQGCSLPDPCDSNPCPANSYCSNDWDSYSCSCDPGYYGDNCTNVCDLNPCEHQSVCTRKPSAPHGYTCECPPN-YLGPYCETRIDQPCPRGWWGHPTCGPCNCDVSKGFDPDCNKTSGECHCKENHYRPPGSPTCLLCDCYPTGSLSRVCDPEDGQCPCKPGVIGRQCDRCDNPFAEVTTNGCEVNYDSCPRAIEAGIWWPRTRFGLPAAAPCPKGSFGTAVRHCDEHRG-WLPPNLFNCTSITFSELKGFAERLQRNESGLDSGRSQQLALLLRNATQHTAG-----------------------------------------------------YFGSDVKVAYQLATRLLAHESTQRGFGLSATQDVHFTENLLRVGSALLDTANKRHWELIQQTEG-GTAWLLQHYEAYASALAQNMRHTYLSPFTIVTPNIVISVVRLDKGNFAG---AKLPRYEALRGEQP-----------------------------PDLETTVILPESVFRETPPVVRPAGPGEAQEPEELARRQRRHPELSQGEAVASVIIYRTLAGLLPHNYDP------------------------------DKRSLRVPKRPIIN--TPVVSISVHDDEELLPRALDKPVT----------------------------------------------------------------------------------------------------------------------VQFRLLETEERTKPICVFWNHSILVSGTG---------------GWSARGCEVVFRNES-----------HVSCQCNHMTSFAVLMDVSRRENGE--ILPLKTLTYVALGVTLAALLLTFFFLTLLRILRSNQHGIRRNLTAALGLAQLVFLLGIN----QADLPFACTVIAILLHFLYLCTFSWALLEALHLYRALTEVRDVNTGPMRFYYMLGWGVPAFITGLAVGLDPEGYGNPDFCWLSIYDTLIWSFAGPVAFAVSMSVFLYILAARASCAAQRQGFEKKGPVSGLQPSFAVLLLLSATWLLALLSVNSDTLLFHYLFATCNCIQGPFIFLSYVVLSKEVRKALKLACSRKPSPDPALTTKSTLTS-------------------------------SYNCPSPYADGRLYQPYGDSAGSLHSTSRSGKSQPSYIPFLLREESALNPGQGPPGLGDPG---------SLFLEGQDQQHDPDTDSDSDLSLEDDQSGSYASTHSSDS---------------------------------------------EEEEEEEEEEAAFPGEQGWDSLLGPGAERLPLHSTPK------------------------------------------------------------------DGGPGPGKAPWPGDFGTTAKESSGNGAPEERLRENGDALSREGS-----------------------LGPLPGSSAQPHKGILKKKCLPTISEKSSLLRLPLEQCTGSSRG------------------SSASEGSRGGPPPRPPPRQSLQEQLNGVMPIAMSIKAGTVDEDSSGSEFLFFNFLH------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9V5N8-1", "uniprot_id": "STAN_DROME", "id": "Q9V5N8-1", "name": "Protocadherin-like wing polarity protein stan", "aln": "MQTREFPQRPLGLLLVLLVVLLQSSLIKSYLIIVHEDTPPGTVIFNASVYKLGSERHYKINAHKSANFVHHLVSVNHKDGQIQLRKALKCDGIYYPNLFTFYVDSTSNRLRSIDYYSLPVRIFVSGHSCNEDRRIEQELHHHHYEEEDNTGYSKRRRRRSTQEMIQLNGNQLEEVFRQNSTEFRAGDLIFGDSFDNEMRHRILSRKRRAVGSPDPLHLQPALHRRISDAKQWISETYASYAIHTTDKWNQICLRRSQFINSLNAFLPRSVCQHCKVSFLDVNDERFAIEHQSRDLVASRDVCIAESMWKVSITFNIRCDRRDIVDSDHRLKIVYHHQEFNDTDIARRVRRELRNQSPYFEQALYVASVLEEQPAGAAVTTVRARDPEDS---PVVYSMVSLLDSRSQSLFKVDSRTGVVTTSASLDRELMDVHYFRVVATDDSFPPRSGTTTLQVNVLDCNDHSPTFEAEQFEASIREGATVGSTVITLRATDQDIGKNAEIEYGIEAVTDGAGLAQDQEMPIFRIDSRSGVISTRSSLDRETSDSYHLLVTAADLASAQSERRTATASVQVKVLDDNDNYPQFSERTYTVQVPEDQWGGTEDNTVAHIRATDADQGNNAAIRYAIIGGNTQSQFSIDSMSGDVSLVKPLDYESVRSYRLVIRAQDGGSPSRSNTT-QLLVNVIDANDNAPRFYTSQFQESVLENVPVGYNIIRVQAYDSDEGANAEITYSISERDDNFPLAVDPRTGWVQTIKPLDREEQGRFAFQVVAKDGGVPPKSASSSVVITVQDVNDNDPAFNPKYYEANVGEDQPPGTPVTTVTATDPDEDSRLHYEITTGNTRGRFAITSQNGRGLITIAQSLDYKQEKRFLLTVAATDSGGRSDTATVHINITDANNFAPIFENAPYSASVFEDAPVGTTVLVVSATDSDVGVNAQITYSLNEESINGLGSPDPFSINPQTGAIVTNAPLDRETTSGYLLTVTAKDGGNPSLSDTTDVEIGVTDVNDNAPAFKSPLYQASILEDALVGTSVIQVAASDPDVGLNGRIKYLLSDRDIEDGSFVIDPTSGTIRTNKGLDRESVAVFHLTAIAVDKGSPPLSSTVEVQIRLEDVNDSPPTFASDKITLYVPENSPVGSVVGEIHAHDPDEGVNAVVHYSIIGGDDSNAFSLVTRPGSERAQLLTMTELDYESTRKRFELVVRAASPPLRNDAHIEILVTDVNDNAPVLRDFQVIFN----NFRDHFPSGEIGRIPAFDADVSDKLHYRILSGNNANLLRLNSSSGGLVLSPQLNTNVPKFATMEVSVSDGINEAKAIMQLSVRLITEDMLFNSVTVRLNEMTEEAFLSPLLNFFLDGLAAIIPCPKEHIFVFSIQDDTDVSS-RILNVSFSARRPD--VSHEEFYTPQYLQERVYLNRAILARLATVEVLPFDDNLCVREPCLNFEECLTVLKFGNASEFIHSDTVLFRPIYPVNTFACSCPEGFTGSKEHYLCDTEVDLCYSDPCQNGGTCVRREGGYTCVCPSTHTGQNCETGVGHLRPCPSETCEGGLSCLSNYPS------SQPPPYTATCELRARAFGRNSFLTFESLKQRHRFNLKLRFATVQENGLLLYNGRYNELHDFIALEIHEGHVSFSFSLGDHSERISVIQEAKVSDGKWHQVEVVYLNRSVT----LVLDNCDTAIALSGQLGDRWSCANRTTLKLDKRCSLLTET---CHRFLDLTGPLQVGGLPRIPAHFPVTNRDFVGCISDLRIDDRFVDLNSYVADNGTLAGCPQKAPLCQSEPCFNGGTCREGWGTYSCECPEGYAGNSCQDNIPAPWRFSGDGSLSFNPLLRPIQLPWTTSFSLRTRQKEAFLLQIQIGQNSSAAVCLRQGVLYYIFDGE-----PMYLAGAFLSDGEWHRVEIRWQQGS---EIHFSVDYGQRSGSVPMSQKVQGLYVGKIVMGSPDGSIGAVPEASPFEGCIQDVRIGAG----QSVLSRPTIRENVEDGCESRAQCP-DHCPNHSSCQSSWDLSTCECDSGYVGTDCAPICTVRPCASG-VCRANTSLPRGYDCECNSSSRHGDYCEKELQQPCPGGWWGERVCGPCRCDLAQGYHPDCNKTTGQCYCKTNHYQPPNETACLSCDCYSIGSFSGACNPLTGQCECREGVIGRRCDSCSNPYAEVTLSGCEVVYDACPRSFAGGVWWPRTPLGGVAIEGCPPPARGKGQRSCDVQSGSWNTPDMYNCTSEPFVELRRQLSQLEKLELELNSFVAIKMAEQLRKACEAVDRRGASKDQKISGNGRPNRRYKMESSFLLSNGGNVWSHELEMDYLSDELKFTHDRLYGADLLVTEGLLQELINYELMQSGLNLSHSQDKYFIKNLVDAASVILDRKYEAEWRRATELIQRGPDDLVDAFNKYLVVLARSQHDTYTSPFEIVQPNMALGLDIVTTESLFGYEPEQLSEYHRSKYLKPNAFTTESVVLPDTSGFLQHSARQRPVISFPKYNNYILDRRKFDQHTKVLVPLEMLGITPPESDEISQSGRRGSSHDHRAIVAYAQYKDVGQLLPDLYDETITRRWGVDVELATPILSLQILVPSMEREQETQRLEIPSRKIFSSSSPSSSSSSGSTEQQFVEVFDVPKAPTSSSEQQIEDIRITAHEIPPPVSSVEQQEASSDEDGEEREPHIRLNLDDIEFHGNSGEEVISPDSPEMLNPNYEGVSSTGSDEQPKGENEAVYRDRRLVKRQVEITYPSEQMQQTEQVVYRSLGSPHLAQPIKLQMWLDVDSARFGPRSNPQCVRWNSFTNQWTRLGCQTEIPDFDGDFNPAAQQAILVNCSCTHISSYAVIVDVIDPEDIPEPSLLVQITSYSAFLVSLPLLLGVLLALALLRGQQTNSNTIHQNIVLCVFCAELLFFVGMQSRRQLLESEFPCKLTAICLHYFWLAAFAWTTVDCVHLYRMLTEMRDINHGPMGFYFAMGYGAPAIVVGLSVGVRAHEYGNSLFCWLSVYEPVVWWLVGPIAGMSVVNLLILFVSVKAAFTLKDHVLGFGNLRTLLWLSVVSLPLMGVMWVLAVLAASEHSQLLSLLLSGVVLLHALFCLIGYCIINKRVRENLQRTCLRCMGRKVPLLDSSMVVSNSSHNVNAAARPSNFLASGYDTTTRRNIGISASSTTSRSTAKTSSSPYSDGQLRQTSTSTSNYNSASDAPSFLRGFESSTTGRSRGGEEKPSRRQRKDSDSGSETDGRSLELASSHSSDDDESRTARSSGTHRSTAVSSTPAYLPNITEHVQATTPPELNVVQSPQLFPSVNKPVYAPRWSSQLPDAYLQSPPNIGRWSQDTGSDNEHVHGQAKMTISPNPLPNPDLTDTSYLQQHHNKINMPPSILENIRDAREGYEDSLYGRRGEYPDKYGSYKPPSHYGSEKDYPGGGSGSQTIGHMRSFHPDAAYLSDNIYDKQRTLGSGYLGAKSESPYLSKDRITPDIYGSRDGHYSLKRQPAYATDSLHSVHSLLKNDYHQQQQQQQQHHLQDRLSEGSDKNGYHFPYTAEEDHLPARKLSHTQPPSLHGSQLMQPPGVGLVNDVNNPGLMGRHTLNGGSRHSSRASSPPSTMVAPMQPLGPLTSITDTERNIDDDETTV", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * .* *::**:*.* *. **** :** *.******* * **.*: **. ***:*::*:* * *****: * :.. * **.*:::.*** :** : ****.** : * * ***** ** :.:** : : ****.**.* .*:: ::* ****:* .*..: * *****.** : *.*: *: .:.*.* .* :* ::.:**** * .: **::*:*.** . * :.: : * ***.*** :*:::** * . **.* ***:**.*.*:**.* * : **: .*: **:*:* * ** *:.* * * *.* ****::...* * * :**::** :*:*:**::*: * ******.:*::.:** :. * :*:.**.:* ***... :*****:*. :* . * ..: ****:****::*: ::: .*******:*:**** *: .*::**:*..:: ** *.:******:**. : * ** **** *:******** ** * * *******:* . :**::**... * *.. .*:.* :*:. . .. .. *:: :*:* .**:**..*:**.:*.* * *** :.:********:** ***:***: : :*.::** *: : :* : . ****:** *:: * *:.: * . .: :*: * . * * *.: .. * .:: ******* :**:* :* *** *.****: :*::*.*.:*: .::*:***:.*** * :*:*. *.***** : *.::***** *:.*:** :::. * :* *.. :::: * **. ** *: :**** :..*** .*: :: ** * : .:* .: * . .**:**:.:: .. . :*.****: .. :. :::**::.::.:*. *. ..*... *.**:*.**:. .*: . *** **. * : ** :* *...** :*.* ** * :*: :* :.** .* :.. *:** *** .. * ***..::**** ****. .****.**:::*:.******:*:*:** ***:**...:** ****. **:* .*:* *** *: *****:** *.**:**** .**** **:***:: .*:***** :* * ** : *.. * ** : * * .*:::**** .* **: .:*:: * *:* : ::* **:* : . :*:*: *: * .*: :* * *:.** :** :* :**: ..*.:** : .*. : *. *:: :: * .**:. :.** *** ** **:.:.: : . .: * :*..*. : :* *. :. :: ... :. :* * : .: :. *: . : .*:.: *: :. ***. ** :.: *.:*.* ::. :* * * . *: : ..:* * : * :* * : . ::** : .: : * *: **:. : : . *.*.*.*::*:**::*: *: * :: :* *: *:*. *: .:: *:*** ::*.: *::*:. .: *:*:*::*:: : *.*.: ** **:::*.:*:*: ::.:**** ***:**:* .** **: :*:*.**::.**:**: .. ***. *****:*:.::* :.**:* :.::: :::.:*: : : : : . : * *.. * *:.. *:**:*:....: *: *:: ::. * ::.* ::.*.**: *: :* * . . .* .* :.* : . .* : .**.*. *:* *. ...* * :** .: ..*: * .*. . :*: : .. .**.* * .**:: ** *.: : :. . :. : * *. * ::.: ..* .**.*. . .* . : *.. ::* .* ::. * * ...: * *: .::.. :* . **.:. * . * *. ** .* :::*. :. * ..* .*. . ", "identical_positions": 753, "similar_positions": 719, "identity": "20.82%" }, { "cls_id": "homologset.agr.MGI:1858236", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O88278-1", "uniprot_id": "CELR3_RAT", "id": "O88278-1", "name": "Cadherin EGF LAG seven-pass G-type receptor 3", "aln": "-----MARRPLWWGLPGPSTPLLLLLLFSLFPSSREE----------------------------MGGGGDQGWDPGVATATGPR---------AQIGSGAVALCPESPG-------------------VWEDGDPGLG------VREPVFMKLRVGRQNARNGRG----------------------------------------------APEQPNREP----VVQALG---------------------SREQEAGQGSGYLLCWHP------------EISSCGR---------------------------------------------------------------TGHLRRGSLP-----------------------LDALSPGDSDLRNSSPHPS-----------ELLAQPDSPR---------------------------PVAFQRNGRRS-----------------------------------------------------IRKRVETFRCCGKLWEPG-HKGQGERSATSTVDRGPLR--RDCLPGSLGSGLGEDSAPRAVRTAPAPG--------------------------------SAPHESRTAPE----RMRSRG-------------LFRRGFLFERPGPRPPGFPTG---AEAKRILSTN-------------------QARSRRAANRHPQFPQYNYQTLVPENEAAGTAVLRVVAQDPDPGEAGRLVYSLAALMNSRSLELFSIDPQSGLIRTAAALDRESMERHYLRVTAQDHGSPRLSATTMVAVTVADRNDHAPVFEQAQYRETLRENVEEGYPILQLRATDGDAPPNANLRY----RFVGSPAARTAAAAAFEIDPRSGLISTSGRVDREHMESYELVVEASDQGQEPGPR-SATVRVHITVLDENDNAPQFSEKRYVAQVREDVR---PHTVVLRVTATDKDKDANGLVHYNIISGNSRGHFAIDSLTGEIQVMAPLDFEAEREYALRIRAQDAGRPPLSNNTGLASIQVVDINDHSPIFVSTPFQVSVLENAPLGHSVIHIQAVDADHGENSRLEYSLTGVASDTPFVINSATGWVSVSGPLDRESVEHYFFGVEARDHGSPPLSASASVTVTVLDVNDNRPEFTMKEYHLRLNEDAAVGTSVVSVTAVDRDANSAISYQITGGNTRNRFAISTQGGMGLVTLALPLDYKQERYFKLVLTASDR-ALHDHCYVHINITDANTHRPVFQSAHYSVSMNEDRPVGSTVVVISASDDDVGENARITYLLEDN-------LPQFRIDADSGAITLQAPLDYEDQVTYTLAITARDNGIPQKADTTYVEVMVNDVNDNAPQFVASHYTGLVSEDAPPFTSVLQISATDRDAHANGRVQYTFQNGEDGDGDFTIEPTSGIVRTVRRLDREAVPVYELTAYAVDRGVPPLRTPVSIQVTVQDVNDNAPVFPAEEFEVRVKENSIVGSVVAQITAVDPDDGPNAHIMYQIVEGNIPELFQMDIFSG----ELTALIDLDYEAR-QEYVIVVQATSAPLVSRATVHVRLVDQNDNSPVLNNFQILFNNYVSNRSDTFPSGIIGRIPAYDPDVSDHLFYSFERGNELQLLVVNQTSGELRLSRKLDNNRPLVASMLVTVTDGLHSVTAQCVLRVVIITEELLANSLTVRLENMWQERFLSPLLGHFLEGVAAVLATPTEDVFIFNIQNDTDVGGTVLNVSFSALAPRGAGAGAAGPWFSSEELQEQLYVRRAALAARSLLDVLPFDDNVCLREPCENYMKCVSVLRFDSSAPFLASASTLFRPIQPIAGLRCRCPPGFTG----DFCETELDLCYSNPCRNGGACARREGGYTCVCRPRFTGEDCELDTEAGRCVPGVCRNGGTCTNAPNGGFRCQCPAGGAFEGPRCEVAARSFPPSSFVMFRGLRQRFHLTLSLSFATVQPSGLLFYNGRLNEKHDFLALELVAGQVRLTYSTGESSTVVSPTVPGGLSDGQWHTVHLRYYNKPRTDALGGAQGPSKDKVAVLSVDDCNVAVALRFGAEIGNYSCAAAGVQTSSKKSLDLTGPLLLGGVPNLPENFPVSRKDFIGCMRDLHIDGRRVDMAAFVANNGTTAGCQAKSHFCASGPCKNGGLCSERWGGFSCDCPVGFGGKDCRLTMAHPYHFQGNGTLSWDFGNDMPVSVPWYLGLSFRTRATKGVLMQVQLGPHSVLLCKLDQGLLSVTLSRASGHAVHLLLDQMTVSDGRWHDLRLELQEEPGGRRGHHIFMVSLDFTLFQDTMAMGSELEGLKVKHLHVGGPPPSSKEEGPQG-LVGCIQGVWTGFTPFGSSALPPPSHRINVEPGCTVTNPCASGPCPPHANCKDLWQTFSCTCWPGYYGPGCVDACLLNPCQNQGSCRHLQGGPHGYTCDCASG-YFGQHCEHRMDQQCPRGWWGSPTCGPCNCDVHKGFDPNCNKTSGQCHCKEFHYRPRGSDSCLPCDCYPVGSTSRSCAPHSGQCPCRPGALGRQCNSCDSPFAEVTASGCRVLYDACPKSLRSGVWWPQTKFGVLATVPCPRGALGLRGTGAAVRLCDEDHG-WLEPDFFNCTSPAFRELSLLLDGLELNKTALDTVEAKKLAQRLREVTGQT-----------------------------------------------------DHYFSQDVRVTARLLAYLLAFESHQQGFGLTATQDAHFNENLLWAGSALLAPETGDLWAALGQRAPGGSPGSAGLVRHLEEYAATLARNMDLTYLNPVGLVTPNIMLSIDRME-----------------------------------------QPSSSQGAHRYPRYHSNLFRGQDAWDPHTHVLLPSQSP--------------------------------------------------------------------------------QPSPSEVLPTSSN-------AENATASGVVSPPAP--LEPESEPGISIVILLVYRALGGLLPAQFQAERRGARLPQNPVMNSPVVSVAVFRGRNFLRG---------------------------------------------------------------ALVSPINLEFRLLQTAN----RSKAICVQWD-PPGPADQHGMWTAR-----DCELVHRNGSHARCRCSRTGTFGVLMDASPRERLEGDLELLAVFTHVVVAASVTALVLTAAVLLSLRSLKSNVRGIHANVAAALGVAELLFLLGIHR----THNQLLCTVVAILLHYFFLSTFAWLLVQGLHLYRMQVEPRNVDRGAMRFYHALGWGVPAVLLGLAVGLDPEGYGNPDFCWISIHEPLIWSFAGPIVLVIVMNGIMFLLAARTSCSTGQREAKKTSVLRTLRSSFLLLLLVSASWLFGLLAVNHSVLAFHYLHAGLCGLQGLAVLLLFCVLNADARAAWTPACLGKKAAPEET-RPAPGPGSGAYNNTALFEESGLIRITLGASTVSSVSSARSGRAQDQDSQRGRSYLRDNVLVRHGSTAEHAEHSLQAHAGPTDLDVAMFHRDAG----------ADSDSDSDLSLEEERSLSIPSSESEDNGRTRGRFQRPLRRAAQSERLLAHP-----KDVDGNDLLSYWPALGECEAAPCALQAWGSERRLGLDSNKDAANNNQPELALTSGDETSLGRAQRQRKGILKNRLQYPLVPQ-----TRGTPELSWCRAATLGHRAVPAASYGRIYAGGGTGSLSQPASRYSSREQLDLLLRRQLSRERLEEVPVPAPVLHPLSRPGSQERLDTAPARLEPRDRGSTLPRRQPPRDYPGTMAG-RFGSRDALDLGAPREWLSTLPPPRRNRD-------LDPQHPPLPLSPQRPLSR-DPLLPSRPLDSLSRISNSRERLDQVPSRHPSREALGPAPQLLRAREDPASGPSHGPSTEQLDILSSILASFNSSALSSVQSSSTPSGPHTTATPSATASALGPSTPRSATSHSISELSPDSEVPRSEGHS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q91ZI0-1", "uniprot_id": "CELR3_MOUSE", "id": "Q91ZI0-1", "name": "Cadherin EGF LAG seven-pass G-type receptor 3", "aln": "-----MARRPLWWGLPGPSTPVLLLLLLSLFPFSREE----------------------------LGGGGDQDWDPGVATTTGPR---------AQIGSGAVALCPESPG-------------------VWEDGDPGLG------VREPVFMRLRVGRQNARNGRG----------------------------------------------APEQPNAEV----VVQALG---------------------SREQEAGQGPGYLLCWHP------------EISSCGR---------------------------------------------------------------TGPLRRGSLP-----------------------LDALSPGDSDLRNSSPHPS-----------ELLAQPDGSR---------------------------PVAFQRNARRS-----------------------------------------------------IRKRVETSRCCGKLWEPG-HKGQGERSATSTVDRGPFR--RDCLPGSLGSGLGEDSAPRAVRTAPTPG--------------------------------SAPRESRTAPG----RMRSRG-------------LFRRRFLFERPGPRPPGFPTG---PEAKQILSTN-------------------QARPRRAANRHPQFPQYNYQTLVPENEAAGTSVLRVVAQDPDPGEAGRLIYSLAALMNSRSLELFSIDPQSGLIRTAAALDRESMERHYLRVTAQDHGSPRLSATTMVAVTVADRNDHAPVFEQAQYRETLRENVEEGYPILQLRATDGDAPPNANLRY----RFVGSPAVRTAAAAAFEIDPRSGLISTSGRVDREHMESYELVVEASDQGQEPGPR-SATVRVHITVLDENDNAPQFSEKRYVAQVREDVR---PHTVVLRVTATDKDKDANGLVHYNIISGNSRGHFAIDSLTGEIQVMAPLDFEAEREYALRIRAQDAGRPPLSNNTGLASIQVVDINDHAPIFVSTPFQVSVLENAPLGHSVIHIQAVDADHGENSRLEYSLTGVASDTPFVINSATGWVSVSGPLDRESVEHYFFGVEARDHGSPPLSASASVTVTVLDVNDNRPEFTMKEYHLRLNEDAAVGTSVVSVTAVDRDANSAISYQITGGNTRNRFAISTQGGVGLVTLALPLDYKQERYFKLVLTASDR-ALHDHCYVHINITDANTHRPVFQSAHYSVSMNEDRPVGSTVVVISASDDDVGENARITYLLEDN-------LPQFRIDADSGAITLQAPLDYEDQVTYTLAITARDNGIPQKADTTYVEVMVNDVNDNAPQFVASHYTGLVSEDAPPFTSVLQISATDRDAHANGRVQYTFQNGEDGDGDFTIEPTSGIVRTVRRLDREAVPVYELTAYAVDRGVPPLRTPVSIQVTVQDVNDNAPVFPAEEFEVRVKENSIVGSVVAQITAVDPDDGPNAHIMYQIVEGNIPELFQMDIFSG----ELTALIDLDYEAR-QEYVIVVQATSAPLVSRATVHVRLVDQNDNSPVLNNFQILFNNYVSNRSDTFPSGIIGRIPAYDPDVSDHLFYSFERGNELQLLVVNRTSGELRLSRKLDNNRPLVASMLVTVTDGLHSVTAQCVLRVVIITEELLANSLTVRLENMWQERFLSPLLGHFLEGVAAVLATPTEDVFIFNIQNDTDVGGTVLNVSFSALAPRGAGAGAAGPWFSSEELQEQLYVRRAALAARSLLDVLPFDDNVCLREPCENYMKCVSVLRFDSSAPFLASTSTLFRPIQPIAGLRCRCPPGFTG----DFCETELDLCYSNPCRNGGACARREGGYTCVCRPRFT--DCELDTEAGRCVPGVCRNGGTCTNAPNGGFRCQCPAGGAFEGPRCEVAARSFPPSSFVMFRGLRQRFHLTLSLSFATVQPSGLLFYNGRLNEKHDFLALELVAGQVRLTYSTGESNTVVSPTVPGGLSDGQWHTVHLRYYNKPRTDALGGAQGPSKDKVAVLSVDDCNVAVALQFGAEIGNYSCAAAGVQTSSKKSLDLTGPLLLGGVPNLPENFPVSHKDFIGCMRDLHIDGRRMDMAAFVANNGTMAGCQAKSHFCASGPCKNNGFCSERWGGFSCDCPVGFGGKDCRLTMAHPYHFQGNGTLSWDFGNDMAVSVPWYLGLSFRTRATKGILMQVQLGPHSVLLCKLDRGLLSVTLNRASGHTVHLLLDQMTVSDGRWHDLRLELQEEPGGRRGHHIFMVSLDFTLFQDTMAMGGELQGLKVKQLHVGGLPPSSKEEGHQG-LVGCIQGVWIGFTPFGSSALLPPSHRVNVEPGCTVTNPCASGPCPPHADCKDLWQTFSCTCRPGYYGPGCVDACLLNPCQNQGSCRHLQGAPHGYTCDCVSG-YFGQHCEHRVDQQCPRGWWGSPTCGPCNCDVHKGFDPNCNKTNGQCHCKEFHYRPRGSDSCLPCDCYPVGSTSRSCAPHSGQCPCRPGALGRQCNSCDSPFAEVTASGCRVLYDACPKSLRSGVWWPQTKFGVLATVPCPRGALG-----AAVRLCDEDQG-WLEPDLFNCTSPAFRELSLLLDGLELNKTALDTVEAKKLAQRLREVTGQT-----------------------------------------------------DHYFSQDVRVTARLLAYLLAFESHQQGFGLTATQDAHFNENLLWAGSALLAPETGHLWAALGQRAPGGSPGSAGLVQHLEEYAATLARNMELTYLNPVGLVTPNIMLSIDRME-----------------------------------------HPSSTQGARRYPRYHSNLFRGQDAWDPHTHVLLPSQAS--------------------------------------------------------------------------------QPSPSEVLPTSSN-------AENATASSVVSPPAP--LEPESEPGISIVILLVYRALGGLLPAQFQAERRGARLPQNPVMNSPVVSVAVFHGRNFLRG---------------------------------------------------------------VLVSPINLEFRLLQTAN----RSKAICVQWD-PPGPTDQHGMWTAR-----DCELVHRNGSHARCRCSRTGTFGVLMDASPRERLEGDLELLAVFTHVVVAVSVTALVLTAAVLLSLRSLKSNVRGIHANVAAALGVAELLFLLGIHR----THNQLLCTAVAILLHYFFLSTFAWLLVQGLHLYRMQVEPRNVDRGAMRFYHALGWGVPAVLLGLAVGLDPEGYGNPDFCWISIHEPLIWSFAGPIVLVIVMNGTMFLLAARTSCSTGQREAKKTSVL-TLRSSFLLLLLVSASWLFGLLAVNHSILAFHYLHAGLCGLQGLAVLLLFCVLNADARAAWTPACLGKKAAPEET-RPAPGPGSGAYNNTALFEESGLIRITLGASTVSSVSSARSGRAQDQDSQRGRSYLRDNVLVRHGSTAEHTERSLQAHAGPTDLDVAMFHRDAG----------ADSDSDSDLSLEEERSLSIPSSESEDNGRTRGRFQRPLRRAAQSERLLAHP-----KDVDGNDLLSYWPALGECEAAPCALQAWGSERRLGLDSNKDAANNNQPELALTSGDETSLGRAQRQRKGILKNRLQYPLVPQ-----SRGTPELSWCRAATLGHRAVPAASYGRIYAGGGTGSLSQPASRYSSREQLDLLLRRQLSKERLEEVPVPAPVLHPLSRPGSQERLDTAPARLEARDRGSTLPRRQPPRDYPGTMAG-RFGSRDALDLGAPREWLSTLPPPRRNRD-------LDPQHPPLPLSPQRQLSR-DPLLPSRPLDSLSRISNSREGLDQVPSRHPSREALGPAPQLLRAREDPASGPSHGPSTEQLDILSSILASFNSSALSSVQSSSTPSGPHTTAT----ASALGPSTPRSATSHSISELSPDSEVPRSEGHS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9NYQ7-1", "uniprot_id": "CELR3_HUMAN", "id": "Q9NYQ7-1", "name": "Cadherin EGF LAG seven-pass G-type receptor 3", "aln": "----MMARRPPWRGLGGRSTPILLLLLLSLFPLSQEE----------------------------LGGGGHQGWDPGLAATTGPR---------AHIGGGALALCPESSG-------------------VREDGGPGLG------VREPIFVGLRGRRQSARNSRG----------------------------------------------PPEQPNEELGIEHGVQPLG---------------------SRERETGQGPGSVLYWRP------------EVSSCGR---------------------------------------------------------------TGPLQRGSLS-----------------------PGALSSGVPGSGNSSPLPS-----------DFLIRHHGPK---------------------------PVSSQRNAGTG-----------------------------------------------------SRKRVGTARCCGELWATG-SKGQGERATTSGAERTAPR--RNCLPGASGSGPELDSAPRTARTAPASG--------------------------------SAPRESRTAPEPAPKRMRSRG-------------LFRCRFLPQRPGPRPPGLPAR---PEARKVTSAN-------------------RARFRRAANRHPQFPQYNYQTLVPENEAAGTAVLRVVAQDPDAGEAGRLVYSLAALMNSRSLELFSIDPQSGLIRTAAALDRESMERHYLRVTAQDHGSPRLSATTMVAVTVADRNDHSPVFEQAQYRETLRENVEEGYPILQLRATDGDAPPNANLRY----RFVGPPAARAAAAAAFEIDPRSGLISTSGRVDREHMESYELVVEASDQGQEPGPR-SATVRVHITVLDENDNAPQFSEKRYVAQVREDVR---PHTVVLRVTATDRDKDANGLVHYNIISGNSRGHFAIDSLTGEIQVVAPLDFEAEREYALRIRAQDAGRPPLSNNTGLASIQVVDINDHIPIFVSTPFQVSVLENAPLGHSVIHIQAVDADHGENARLEYSLTGVAPDTPFVINSATGWVSVSGPLDRESVEHYFFGVEARDHGSPPLSASASVTVTVLDVNDNRPEFTMKEYHLRLNEDAAVGTSVVSVTAVDRDANSAISYQITGGNTRNRFAISTQGGVGLVTLALPLDYKQERYFKLVLTASDR-ALHDHCYVHINITDANTHRPVFQSAHYSVSVNEDRPMGSTIVVISASDDDVGENARITYLLEDN-------LPQFRIDADSGAITLQAPLDYEDQVTYTLAITARDNGIPQKADTTYVEVMVNDVNDNAPQFVASHYTGLVSEDAPPFTSVLQISATDRDAHANGRVQYTFQNGEDGDGDFTIEPTSGIVRTVRRLDREAVSVYELTAYAVDRGVPPLRTPVSIQVMVQDVNDNAPVFPAEEFEVRVKENSIVGSVVAQITAVDPDEGPNAHIMYQIVEGNIPELFQMDIFSG----ELTALIDLDYEAR-QEYVIVVQATSAPLVSRATVHVRLVDQNDNSPVLNNFQILFNNYVSNRSDTFPSGIIGRIPAYDPDVSDHLFYSFERGNELQLLVVNQTSGELRLSRKLDNNRPLVASMLVTVTDGLHSVTAQCVLRVVIITEELLANSLTVRLENMWQERFLSPLLGRFLEGVAAVLATPAEDVFIFNIQNDTDVGGTVLNVSFSALAPRGAGAGAAGPWFSSEELQEQLYVRRAALAARSLLDVLPFDDNVCLREPCENYMKCVSVLRFDSSAPFLASASTLFRPIQPIAGLRCRCPPGFTG----DFCETELDLCYSNPCRNGGACARREGGYTCVCRPRFTGEDCELDTEAGRCVPGVCRNGGTCTDAPNGGFRCQCPAGGAFEGPRCEVAARSFPPSSFVMFRGLRQRFHLTLSLSFATVQQSGLLFYNGRLNEKHDFLALELVAGQVRLTYSTGESNTVVSPTVPGGLSDGQWHTVHLRYYNKPRTDALGGAQGPSKDKVAVLSVDDCDVAVALQFGAEIGNYSCAAAGVQTSSKKSLDLTGPLLLGGVPNLPENFPVSHKDFIGCMRDLHIDGRRVDMAAFVANNGTMAGCQAKLHFCDSGPCKNSGFCSERWGSFSCDCPVGFGGKDCQLTMAHPHHFRGNGTLSWNFGSDMAVSVPWYLGLAFRTRATQGVLMQVQAGPHSTLLCQLDRGLLSVTVTRGSGRASHLLLDQVTVSDGRWHDLRLELQEEPGGRRGHHVLMVSLDFSLFQDTMAVGSELQGLKVKQLHVGGLPPGSAEEAPQG-LVGCIQGVWLGSTPSGSPALLPPSHRVNAEPGCVVTNACASGPCPPHADCRDLWQTFSCTCQPGYYGPGCVDACLLNPCQNQGSCRHLPGAPHGYTCDCVGG-YFGHHCEHRMDQQCPRGWWGSPTCGPCNCDVHKGFDPNCNKTNGQCHCKEFHYRPRGSDSCLPCDCYPVGSTSRSCAPHSGQCPCRPGALGRQCNSCDSPFAEVTASGCRVLYDACPKSLRSGVWWPQTKFGVLATVPCPRGALG-----AAVRLCDEAQG-WLEPDLFNCTSPAFRELSLLLDGLELNKTALDTMEAKKLAQRLREVTGHT-----------------------------------------------------DHYFSQDVRVTARLLAHLLAFESHQQGFGLTATQDAHFNENLLWAGSALLAPETGDLWAALGQRAPGGSPGSAGLVRHLEEYAATLARNMELTYLNPMGLVTPNIMLSIDRME-----------------------------------------HPSSPRGARRYPRYHSNLFRGQDAWDPHTHVLLPSQSP--------------------------------------------------------------------------------RPSPSEVLPTSSS-------IENSTTSSVVPPPAP--PEP--EPGISIIILLVYRTLGGLLPAQFQAERRGARLPQNPVMNSPVVSVAVFHGRNFLRG---------------------------------------------------------------ILESPISLEFRLLQTAN----RSKAICVQWD-PPGLAEQHGVWTAR-----DCELVHRNGSHARCRCSRTGTFGVLMDASPRERLEGDLELLAVFTHVVVAVSVAALVLTAAILLSLRSLKSNVRGIHANVAAALGVAELLFLLGIHR----THNQLVCTAVAILLHYFFLSTFAWLFVQGLHLYRMQVEPRNVDRGAMRFYHALGWGVPAVLLGLAVGLDPEGYGNPDFCWISVHEPLIWSFAGPVVLVIVMNGTMFLLAARTSCSTGQREAKKTSAL-TLRSSFLLLLLVSASWLFGLLAVNHSILAFHYLHAGLCGLQGLAVLLLFCVLNADARAAWMPACLGRKAAPEEA-RPAPGLGPGAYNNTALFEESGLIRITLGASTVSSVSSARSGRTQDQDSQRGRSYLRDNVLVRHGSAADHTDHSLQAHAGPTDLDVAMFHRDAG----------ADSDSDSDLSLEEERSLSIPSSESEDNGRTRGRFQRPLCRAAQSERLLTHP-----KDVDGNDLLSYWPALGECEAAPCALQTWGSERRLGLDTSKDAANNNQPDPALTSGDETSLGRAQRQRKGILKNRLQYPLVPQ-----TRGAPELSWCRAATLGHRAVPAASYGRIYAGGGTGSLSQPASRYSSREQLDLLLRRQLSRERLEEA--PAPVLRPLSRPGSQECMDAAPGRLEPKDRGSTLPRRQPPRDYPGAMAG-RFGSRDALDLGAPREWLSTLPPPRRTRD-------LDPQPPPLPLSPQRQLSR-DPLLPSRPLDSLSRSSNSREQLDQVPSRHPSREALGPLPQLLRAREDSVSGPSHGPSTEQLDILSSILASFNSSALSSVQSSSTPLGPHTTATPSATASVLGPSTPRSATSHSISELSPDSEVPRSEGHS", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M3B4X6-1", "uniprot_id": "A0A8M3B4X6_DANRE", "id": "A0A8M3B4X6-1", "name": "Cadherin EGF LAG seven-pass G-type receptor 3", "aln": "-------MAALLLDLGSLSPLLFLLLLSSLFTVIPGSGAGLCCRSRCTHPAPGDAQIASLPDGTITGALALGDWKIYPARTVGSRGRELQCSRSSAAGTPSVSLSPDYRNSSVWISEPAAHTGRCHRQPVWSDGGSGEKGVVSRVLASPVQYGKKRTVQRTRTRWRPKTRTVSFGTDSVFAHSVLDNCRTLDNKPRPNHCPYHPKREFAFAKTPTQPLLKAYSYSNVASDANKLHKATAHHPLSAPLNVIDLTREDWNGSSFGYVRGSSEPCARQLSPVLESETSSCLESYWITGCSERHPAWHSSYWHRFNISLMRYGVCVRQARENTNTTSSYNNSKAQFVHKKSHPNNPHGALRRDLISRVDCIRTDTRFDDRKANYNRSTGISAAPSYNGDVYNSDSSATGTPRGHNASQIYLLVELNFSKRFRDSYTHTRVIRSERAKDSAPGQWTAPFAVHEHAYSSDSTKSLFLMNWNTNNNNNCDKNHNNNNNNNNSSPGDQNANETQNVPDSNEREFIRGESARFPCSGARAERGDYKTDDSLNADGGATRPQLKSGKRVSLQAEGVSQQEEQLEAAAECGRREGQIEGGVKGEGRGEGDRQPVDGEWEESMEWVIAEDTKEERVLEGTNLQRKKEKGQGNDTSQSERESDDIKEGMWTEQNETKQSEVGVGNQYSEKQKYKDSDEVLREEGQEYSEEQTGIPSAGRSRRAANRQPQFPQYNYQVQVAENQPPGTSVIAMTAEDHDAGEAGRLSYSMAPLMNSRSMDYFQIDPITGLLTTTHILDREHMDLHYFRVTAADHGSPHLSGTTMVTITVADRNDHSPVFEQTEYRETIRENVEEGYPILQLRATDLDSTANANIRY----RFVGESAA--VARSAFEIDPRSGLITTRGIVDRETNERYTLLVEASDQGREPGPR-SATVSVHITVLDENDNVPQFSQKRYVVAVREDVR---PHSEILRISATDQDKDGNAAVHYNIISGNSRGQFAIDSVTGEIQVVAPLDFETEREYTLRLRAQDNGRPPLSNNTGIVSVQVTDVNDNPPIFVSTPFQATVLESAPIGHSILHIQAIDTDNGDNARLEYRLTGTGTDTPFVINAATGWVTVSSELDRESVEHYFFGVEARDYGSPPLSATASVTITVMDVNDNRPEFLQKEYYVRLNEDAAVGTSVVSVTAVDRDVNSAVTYQITGGNTRNRFAISTAGGAGLVSLALPLDYKQERRYVLTVTASDR-TLHDTCQVHINITDANTHRPVFQSAHYSVSVNEDRPPGSTVVVISATDDDVGENARITYYLEDN-------IPQFRIDPASGAITLQAELDYEDQMTYTLAITARDNGIPQKSDTTYVEVNVNDVNDNAPQFLSPRYQGGVSEDAPPFTSVLQISATDRDAHANGRVQYTFQNGEDGDGDFTIEPTSGIVRTVRRLDRESVPFYELTAFAVDRGVPPQRTPVHIQVSVMDVNDNAPVFPADDFEVLVKENSAVGSVVAQITATDPDEGPNAQIMYQIVEGNIPEIFQMDIFSG----ELTSLIDLDYETR-NEYVIVVQATSAPLVSRATVRIRLVDQNDNGPQMQDFQIIFNNFVSNRSNTFPSGVIGRVPAHDPDVSDRLYYTIDRGNELHLLLLNHTSGEIRLSRKLDNNRPLVAPMLITVTDGIHSVSAQCVLRVLIITEEMLSSSITVRLQNMSQELFLSPLLTHFLDGVSAVLSVSPDDVFVFNVQPDADAG-KVLNVSFSAALP-------GGQFFPSEALEEQLYLNRPRLNALAHMEVLPFDDNVCLREPCQNYMKCISVLRFNSSAPFIASPSTLFRPIHPITGLRCRCPAGFTG----DYCEIEINLCYSNPCMNGGVCARREGGYTCICREDYTGERCEFDRRGGRCVAGVCRNGGTCRELSGGGFRCECPAG-GYEKPYCSVTTRSFPPKSFMMFRGLRQRFHLSISLSFATLESNGLLFYNGRFNEKHDFLALEILDGQMVLKYSTGESSTQVSPYLPGGVSDGNWHTVHIHYYNKPKRSVSGEVQGPSDEKVAVLSVDDCDTAVSLRFGAQLGNYSCAAQGRQTSSKKSLDLTGPLFLGGVPNLPENFPFSTREFIGCMKDLHIDNRPVDMAGFIANNGTLPGCSAKLPFCKSNPCQNGGTCRVSWETFSCDCPVGFGGKDCSLVMSHPHRFLGSSALWWDLKNEVTITTPWYMGLVFRTRSKEGVLLQAQAGQYTNLIFQVVGGQLVFSVARGSTRPVRLRLDQVQVCDGRWHDLQLELRDVRSGRETRYIATVRLDFGLYQGTVIVGNEINGVKVKHLHVGGVLGSG--EVQNG-IRGCIQGVRLGVRP-DSPALPRPSRTIKVETGCNVGNPCNSSPCPTHSQCTDEWDRHTCVCEPGFYGKSCMDACQLNPCENQAKCHRKPSSSHGYICDCEDS-HYGQYCQHRIEQQCPRGWWGSPTCGPCHCDASKGFDTDCNKTTGHCHCKEFHYRRRGSDICLPCDCYPVGSFSRSCDPESGQCQCRPGVIGRQCNMCDNPFAEVTQTGCEVIYDGCPKTITSAIWWPRTKFNLPAAVPCPKGSVG-----TAIRHCDGERG-WLDPDLYNCTSPPFVELNTALESLERNETELNTIIEKKLAHQLRDVTEAT-----------------------------------------------------SRLYGNDLQIAERLLSRLLTFESLQSGFGLTATQDAHFNENVLRGCSVLLGPASASLWRAQ----SSGQSGAAGLADLLEQYTRILAQNMKQTYLNPVALVAPNIVMTLDRVD-----------------------------------------NHTHVR--RRFPRYHSPLFRGQALWDAHTHVVLPPAAL--------------------------------------------------------------------------------VPQRNVFSAPSPAG------PVNLLANQTLEATAARRSLSLQEAPVSIVIILIYRSLGAALPPKYHTDRRGVRLPRHPVLNSPVVSISVYNNQTFVEG---------------------------------------------------------------FLESPVLLEFRLLETSN----RSKPLCVQWN-HSSIVSGGGCWTVR-----DCSVLYRNTSHVRCQCHRLGTFGVLMDSSQREQLEGDLETLAIVTYSSLSVSMAALLLTVLVLSCLRGLKSNTRSIHSNMAAATLLSHLTYLLGINQ----TEQQFLCTVVAILLHYFFMSAFAWLFVEALHIYRMQTEARNINYGAMRFYYAIGWGVPAIITGLAVGLDPEGYGNPDFCWISMYDKLMWSFAGPVSVVILMNGGMFLMVLRMTCNPTQKEIKKLPVISTIRSAFFLLLLSTCVWLFGLMAVNNSVLAFHYLFIILCCIQGLAVLLVFTVLNSEVQEAWKLACLGKKSPGEEPPRPPQITGQNPYNSASLLEQSGLHRITLGTSTISSVSSAR-----------------ENLLARQ------TLEHTLAHTGATDLDVAMFHRNGGTLTHNNLHACEDSDSDSDLSLEEERSLSIPSSESEDNVRLRGRIQRRFKRTGHGERLLTEATHNGGKDLDGNDLLSYWPALEGCEAH--SLQKWGSERRLGGDYNKDAANNNQPDAALTSGDEN--GLTHRHRKGILKNRLGCPPALQGLSAVGRAPSEMSWYRTSTLGHRGVPAASYGRMYSG--TGSLSQPASRYSSREHLDSLARRQRSRDNLDLLP-RRRELGAEHLGGSRERLGPVHSIHASREDLVGRGGLAGLMGAEGSLSGSRTQLNTLTRQQASREHLGGALMSSRSREQLESNGGAQPCREWLRTLPPRQLSHPDPHPPSSPPPPIT-----EEPHESLPSRRGRLDSAPPCRYPSSSAAAPGAPSSRPPSSEHLDILSSILASFSSSVLTPPPN---PAGPSP-----------SPPPPLSATSQSVSEVSPDSEVNRSDGQS", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9V5N8-1", "uniprot_id": "STAN_DROME", "id": "Q9V5N8-1", "name": "Protocadherin-like wing polarity protein stan", "aln": "MQTREFPQRPLGLLLVLLVVLLQSSLIKSYLIIVHEDTPPG------------------------TVIFNASVYKLGSERHYKIN---------AHKSANFVHHLVSVN---------------------HKDGQIQLR---KALKCDGIYYPNLFTFYVDSTSNR----------------------------------------------LRSIDYYSLPVRIFVSGHS--------------------CNEDRRIEQELHHHHYEEE------------DNTGYSK-------------------------------------------------------------RRRRRSTQEMIQ-----------------------LNGNQLEEVFRQNSTEFRAG----------DLIFGDSFDN---------------------------EMRHRILSRKR---------------------------------------------------RAVGSPDPLHLQPALHRRISDAKQWISETYASYAIHTTDKWNQICLRRSQFINSLNAFLPRSVCQHCKVS------------------------------FLDVNDERFAIEHQSRDLVASRDVCIAES-------MWKVSITFNIRCDRRDIVDSDHRLKIVYHHQEFN--------------DTDIARRVRRELRNQSPYFEQALYVASVLEEQPAGAAVTTVRARDP---EDSPVVYSMVSLLDSRSQSLFKVDSRTGVVTTSASLDRELMDVHYFRVVATDDSFPPRSGTTTLQVNVLDCNDHSPTFEAEQFEASIREGATVGSTVITLRATDQDIGKNAEIEYGIEAVTDGAGLAQDQEMPIFRIDSRSGVISTRSSLDRETSDSYHLLVTAADLASAQSERRTATASVQVKVLDDNDNYPQFSERTYTVQVPEDQWGGTEDNTVAHIRATDADQGNNAAIRYAIIGGNTQSQFSIDSMSGDVSLVKPLDYESVRSYRLVIRAQDGGSPSRSN-TTQLLVNVIDANDNAPRFYTSQFQESVLENVPVGYNIIRVQAYDSDEGANAEITYSISERDDNFPLAVDPRTGWVQTIKPLDREEQGRFAFQVVAKDGGVPPKSASSSVVITVQDVNDNDPAFNPKYYEANVGEDQPPGTPVTTVTATDPDEDSRLHYEITTGNTRGRFAITSQNGRGLITIAQSLDYKQEKRFLLTVAATDSGGRSDTATVHINITDANNFAPIFENAPYSASVFEDAPVGTTVLVVSATDSDVGVNAQITYSLNEESINGLGSPDPFSINPQTGAIVTNAPLDRETTSGYLLTVTAKDGGNPSLSDTTDVEIGVTDVNDNAPAFKSPLYQASILEDALVGTSVIQVAASDPDVGLNGRIKYLLSDRDIEDGSFVIDPTSGTIRTNKGLDRESVAVFHLTAIAVDKGSPPLSSTVEVQIRLEDVNDSPPTFASDKITLYVPENSPVGSVVGEIHAHDPDEGVNAVVHYSIIGGDDSNAFSLVTRPGSERAQLLTMTELDYESTRKRFELVVRAASPPLRNDAHIEILVTDVNDNAPVLRDFQVIFNNFR----DHFPSGEIGRIPAFDADVSDKLHYRILSGNNANLLRLNSSSGGLVLSPQLNTNVPKFATMEVSVSDGINEAKAIMQLSVRLITEDMLFNSVTVRLNEMTEEAFLSPLLNFFLDGLAAIIPCPKEHIFVFSIQDDTDVSSRILNVSFSARRP----DVSHEEFYTPQYLQERVYLNRAILARLATVEVLPFDDNLCVREPCLNFEECLTVLKFGNASEFIHSDTVLFRPIYPVNTFACSCPEGFTGSKEHYLCDTEVDLCYSDPCQNGGTCVRREGGYTCVCPSTHTGQNCETGVGHLRPCPSETCEGGLSCLSNYP------SSQPPPYTATCELRARAFGRNSFLTFESLKQRHRFNLKLRFATVQENGLLLYNGRYNELHDFIALEIHEGHVSFSFSLGDHSERISVIQEAKVSDGKWHQVEVVYLNRSVTLVLDNCDTAIALSGQLGDRWSCANRTTLKLDKRCS-------LLTETCHRFLDLTGPLQVGGLPRIPAHFPVTNRDFVGCISDLRIDDRFVDLNSYVADNGTLAGCPQKAPLCQSEPCFNGGTCREGWGTYSCECPEGYAGNSCQDNIPAPWRFSGDGSLSFNP-LLRPIQLPWTTSFSLRTRQKEAFLLQIQIGQNSSAAVCLRQGVLYYIFDGEP-----MYLAGAFLSDGEWHRVEIRWQQGSE-------IHFSVDYGQRSGSVPMSQKVQGLYVGKIVMGSPDGSIGAVPEASPFEGCIQDVRIGAGQ---SVLSRPTIRENVEDGCESRAQCP-DHCPNHSSCQSSWDLSTCECDSGYVGTDCAPICTVRPCAS-GVCRANTSLPRGYDCECNSSSRHGDYCEKELQQPCPGGWWGERVCGPCRCDLAQGYHPDCNKTTGQCYCKTNHYQPPNETACLSCDCYSIGSFSGACNPLTGQCECREGVIGRRCDSCSNPYAEVTLSGCEVVYDACPRSFAGGVWWPRTPLGGVAIEGCPPPARG-----KGQRSCDVQSGSWNTPDMYNCTSEPFVELRRQLSQLEKLELELNSFVAIKMAEQLRKACEAVDRRGASKDQKISGNGRPNRRYKMESSFLLSNGGNVWSHELEMDYLSDELKFTHDRLYGADLLVTEGLLQELINYELMQSGLNLSHSQDKYFIKNLVDAASVILDRKYEAEWRRATELIQRGP---DDLVDAFNKYLVVLARSQHDTYTSPFEIVQPNMALGLDIVTTESLFGYEPEQLSEYHRSKYLKPNAFTTESVVLPDTSGFLQHSARQRPVISFPKYNNYILD-RRKFDQHTKVLVPLEMLGITPPESDEISQSGRRGSSHDHRAIVAYAQYKDVGQLLPDLYDETITRRWGVDVELATPILSLQILVPSMEREQETQRLEIPSRKIFSSSSPSSSSSSGSTEQQFVEVFDVPKAPTSSSEQQIEDIRITAHEIPPPVSSVEQQEASSDEDGEEREPHIRLNLDDIEFHGNSGEEVISPDSPEMLNPNYEGVSSTGSDEQPKGENEAVYRDRRLVKRQVEITYPSEQMQQTEQVVYRSLGSPHLAQPIKLQMWLDVDSARFGPRSNPQCVRWNSFTNQWTRLGCQTEIPDFDGDFNPAAQQAILVNCSCTHISSYAVIVDVIDPEDIPEPSLLVQITSYSAFLVSLPLLLGVLLALALLRGQQTNSNTIHQNIVLCVFCAELLFFVGMQSRRQLLESEFPCKLTAICLHYFWLAAFAWTTVDCVHLYRMLTEMRDINHGPMGFYFAMGYGAPAIVVGLSVGVRAHEYGNSLFCWLSVYEPVVWWLVGPIAGMSVVNLLILFVSVKAAFTLKDHVLGFGNLRTLLWLSVVSLPLMGVMWVLAVLAASEHSQLLSLLLSGVVLLHALFCLIGYCIINKRVRENLQRTCLRCMGRKVPLLDSSMVVSNSSHNVNAAARPSNFLASGYDTTTRRNIGISASSTTSRSTAKTSSSPYSDGQLRQTSTSTSNYNSASDAPSFLRGFESSTTGRSRGGEEKPSRRQRKDSDSGSETDGRSLELASSHSSDDDESRTARSSGTHRSTAVSSTPAYLPNITEHVQATTPPELNVVQSPQLFPSVNKPVYAPRWSS--QLPDAYLQSPPNIGRWSQDTGSDNEHVHGQAKMTISPNPLPNPDLTDTSYLQQHHNKINMPPSILENIRDAREGYEDSLYGRRGEYPDKYGSYKPPSHYGSEKDYPGGGSGSQTIGHMRSFHPDAAYLSDNIYDKQR---TLGSGYLGAKSESPYLSKDRITPDIYGSRDGHYSLKRQPAYATDSLHSVHSLLKNDYHQQ------------------QQQQQQHHLQDRLSEGSDKNGYHFPYTAEEDHLPARKLS-HTQPPSLHGSQLMQPPGVGLVNDVNNPGLMGRHTLNGGSRHSSRASSPPSTMVAPMQP----------LGPLTSITDTERNIDDDETTV---------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . * : *: * : . :. . : . : . .** . : . . * . ..: . : :. . : : .. ** : :: . . : . . . * . . . : : : : . :. . . * . .:. : : : : . : . : *. *: * * * * . * *::..*::* : *.* * . : **:..*::*** . *.:*. :*:: *: **** *: **:**.* *.. * *.** : :.* * ***:*.** ::. ::**.. * .:: ***** * **::.* * . . *.**.***:*:* . :*** : * *:* *:* . . * :**. *::.***:*** ****:: *.. * ** .. : :: *** *:. *. ::* **.**::.:*:***::*::.:: ***:*: *.* * :**** * *. ** * ::* * **: * * :: ** :***..*:*:.::::** *:*.* *:.: * :: : *:.::. **** . ****. :: * * *:* * ** **::**.:** ***** * * * * .:.** . **.*.:***.* * :* : *:** ****.****:: .* **:::* .******: : *.::*:* * . *********.. *:*:.* **.*: ** * *:*::*:**:*.*** **:*** *::: * *:. :***. :* ** * * *::**:*.* *. :*** **: *.******* * :. * . : *** ***:*::*:* *. ***::* :.: : **.*.*:**** :** : ****:*..:.*** ***:* ** :.* :*: : ****..*.*.::.: : * *** *****.:* * ***:* ** : *.*: *: .: *.: .* :* :: :****: :.: :**:*:*.** . * :.: :.* ***.* :.:**::***: : **** ***:**.*.****:*.* : **: :** :* :** : ** :*:.* * .*.* ::*:**::...* * * :***::* .*:****::* :* ****** **:*::*::. . :.:*:*.:* *:*.. :******* * ::..: *:*::*:.*. * : ::*******:*:**** *: :*::**:*..:: *: * :.***** *: : * ** **** *: *::****:** ***.*.********:* .* ** . * .. :** . .: . *.: :*:* .**: *..*:**.::.:.* ***:: .***:**** ** ***:***: *:: :.:* *: . :* . :***:** *.: * *:. . . : . . : . .* .:*::. . . :.:: ******* :**:*.:* :**.: ::*:**: **:**.* :*: .::*:*** .** * :* * ** *.* * * :**:** *:.*:.* :. * :* *..:* :: .: ** .: :*** .:..*:* * * : : * * . . : * :.**.** :.:. :: . :*: ..:: :. :::*: * :: :*. . . : ****.* * ..* *: :.* ** * . ** *:.* . *: :* * .*: * .* * :.** . . *: . .:** *:* .. .*.:*::.::* ** ****. .****.** :*:..:****.*:*:** **: .. **.****.:** * :* * :*** ** *.:**:*: *..*:**** :**.*:**.**::: ..:***:* :. * ** : * . * ** * * **::**** .* ** *. ** : *::. *:*.:**.. . .: :. *: :: ** *: :* *.*:.*: :** :* :*:: . *.:* * * .*. :::* **:. . ** .*. :* **: : :* : : : : :*:*:. :: : :* **:*::* *. . . ..*. : .. . *. : * : .:.. : ::. * . : :* :.. .. .: * .*: *:: * : **:. **:*: .. * * * . :: ..* * : .::.*::* * : : : :: . .*:. *: . * **. ::* . ** *:. . :.* :::*:: ..:: *. .** ****::::*** *: :*:*** .* *::: *.* **.*:*:*.**:: **:**: .. ***. ***:*::: ::* :.**: : ::* :::: : : . :: : :.. * * *::.::*... : * : ::.* *: : ::* .: :** . .. . ..:* : . *.: .::* .:. : :. * : * : .:: : *. * ****.*: . .. . * **:.::. *. : .. *.. : : * * . *.* :* :...* .: . *.:* * :: . . . . : * . .:.. : *** . . :*.*:*.*.:. . : .: * .: . .:. . *: * . . . : :: : .: * : :*:*: .: * . . .. * :: .. * :. . .* .. : *.:.:.: .. ", "identical_positions": 902, "similar_positions": 987, "identity": "22.37%" }, { "cls_id": "homologset.agr.MGI:1858237", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O35290-1", "uniprot_id": "ECP3_MOUSE", "id": "O35290-1", "name": "Eosinophil cationic-type ribonuclease 3", "aln": "MGPKLLESRLCLLLLLRLVLMLASCLGQTP----SRWFAIQHINNNTNLRCNVEMLRINRFRRTCKGLNTFLHTSFANAVGVCGNPSGLCSDN-ISRNCHNSSSRVHITVCNITSRRRIPYTQCRYQPRRSVEYYTVACNPRTSL-DSPMYPVVPVHLDGTF", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "E9PU07-1", "uniprot_id": "E9PU07_RAT", "id": "E9PU07-1", "name": "", "aln": "MGLKLLESRLCLLLLLG----LVTCQRPTP----SQWFAIQHIYNSSYPQCNAAMLRVNSYTGRCKGINTFLHASFANVVGVCGNPHTTCKDR-ISTNCHNSSSQVSITFCNLTTPARI-YTQCRYQTTGSLKFYTVACNPRTPR-DSPMYPVVPVHLDRIF", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P10153-1", "uniprot_id": "RNAS2_HUMAN", "id": "P10153-1", "name": "Non-secretory ribonuclease", "aln": "MVPKLFTSQICLLLLLGLLAVEGSLHVKPPQFTWAQWFETQHINMTS-QQCTNAMQVINNYQRRCKNQNTFLLTTFANVVNVCGNPNMTCPSNKTRKNCHHSGSQVPLIHCNLTTPSPQNISNCRYAQTPANMFYIVACDNRDQRRDPPQYPVVPVHLDRII", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P12724-1", "uniprot_id": "ECP_HUMAN", "id": "P12724-1", "name": "Eosinophil cationic protein", "aln": "MVPKLFTSQICLLLLLGLMGVEGSLHARPPQFTRAQWFAIQHISLNP-PRCTIAMRAINNYRWRCKNQNTFLRTTFANVVNVCGNQSIRCPHNRTLNNCHRSRFRVPLLHCDLINPGAQNISNCTYADRPGRRFYVVACDNRDPR-DSPRYPVVPVHLDTTI", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* **: *::****** : .* ::** *** .. :*. * :* : **. **** ::***.*.**** * . ***.* :* : *:: . ::* * . :* ***: * *.* ********* :", "identical_positions": 58, "similar_positions": 32, "identity": "35.8%" }, { "cls_id": "homologset.agr.MGI:1858238", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "E9PU07-1", "uniprot_id": "E9PU07_RAT", "id": "E9PU07-1", "name": "", "aln": "MGLKLLESRLCLLLLLG----LVTCQRPTP----SQWFAIQHIYNSSYPQCNAAMLRVNSYTGRCKGINTFLHASFANVVGVCGNPHTTCK-DRISTNCHNSSSQVSITFCNLTTP-ARIYTQCRYQTTGSLKFYTVACNPRTPR-DSPMYPVVPVHLDRIF", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q5GAM3-1", "uniprot_id": "Q5GAM3_RAT", "id": "Q5GAM3-1", "name": "", "aln": "MGLKLLESRLCLLLPLGLVLMLASCQRPTP----SQRFAIQHIYNSAYPQCNAAMQRVNNYTGRCKDINTFLHTSFASVVGVCGNRNTTCNSNRTRTNCHDSTYQVKVTICNLTNR-AAVYPQCPYQTINSSKFYRVACDPRTPR-DNRTYPVVPVHLDFIF", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O35291-1", "uniprot_id": "RNAS2_MOUSE", "id": "O35291-1", "name": "Non-secretory ribonuclease", "aln": "MGPKLLESRLCLLLLLGLVLMLASCQAQIL----SQKFYTQHIYNSTYPRCDAVMRVVNRYRPRCKDINTFLHTSFADVVAVCGHPNITCN-NLTRKNCHASSFQVFITFCNLTMP-TRICTQCRYQTTGSVKYYRVACENRTPQ-DTPMYPVVPVHLDGTF", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P10153-1", "uniprot_id": "RNAS2_HUMAN", "id": "P10153-1", "name": "Non-secretory ribonuclease", "aln": "MVPKLFTSQICLLLLLGLLAVEGSLHVKPPQFTWAQWFETQHIN-MTSQQCTNAMQVINNYQRRCKNQNTFLLTTFANVVNVCGNPNMTCPSNKTRKNCHHSGSQVPLIHCNLTTPSPQNISNCRYAQTPANMFYIVACDNRDQRRDPPQYPVVPVHLDRII", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P12724-1", "uniprot_id": "ECP_HUMAN", "id": "P12724-1", "name": "Eosinophil cationic protein", "aln": "MVPKLFTSQICLLLLLGLMGVEGSLHARPPQFTRAQWFAIQHIS-LNPPRCTIAMRAINNYRWRCKNQNTFLRTTFANVVNVCGNQSIRCPHNRTLNNCHRSRFRVPLLHCDLINPGAQNISNCTYADRPGRRFYVVACDNRDPR-DSPRYPVVPVHLDTTI", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* **: *::**** ** : : :* * *** :* .* :* * ***. **** ::**.** ***: * : .*** * :* : *:* . .:* * . :* ***: * : * ********* :", "identical_positions": 58, "similar_positions": 27, "identity": "35.8%" }, { "cls_id": "homologset.agr.MGI:1858256", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I6GLQ4-1", "uniprot_id": "A0A8I6GLQ4_RAT", "id": "A0A8I6GLQ4-1", "name": "", "aln": "MCHKPVQKMAEHGEASEDQVSEFDGECLPELSALLGVDAVQLVKSQEEEENKERMKMKKGFNAQMRSEAKRLKTFVTYDAFKSWTPQEMAAAGFYYTGVRHGVQCFCCSLILFGTSLRKVPIESHRKLRPQCEFLSGKDVGNIGKYDIRVKNPETLPRGGRARYHEEEARLESFEDWPFYAHGTSPRVLSAAGFVFTGKRDTVQCFSCGGCLGNWEEGDDPWKEHAKWFPKCEFLQSKKSTEEINQYIQSYTGFLHVAGEHFVNSWVRRELPVVSAYSNDSVFANEGLRMDTFKDWPHESSVAVEALVKAGLFYTGKKDIVQCFSCGGCMENWKEGDDPIEDHTKFFPNCVFLQTLKSSAEVIPALQSHCACPEAMETTSESNHEDPVAVHSSVAGLGQSEAQWCQEARSLSEQLRGTYTKASFRHMNLPEAYSSLGTDHLLGCEVFLISKHVSRPVQVALTIPEVFANLSSVMCVEGEAGSGKTTFLKRIAFLWASGCCPLLNRFQLVFYLSLRSIRADQGLADIICAQLLEAGGCISEVSLSSGIQHLQHQVLFLLDDYSGMDSLPQALDTLITKNYLSRTCLLMAVHTNRVRDIRPYLETVLQIKEFPFYNTISVLRKFFSHNTTRLLEFMVYFGRNEDLQGVHKTPLFVAAVCTDWFQNPSDQP-FQDVTIFKSYMQYLFLKHKATAGPLQATVSSCGHLALTGLFSSSFEFSSDDLIEAGVDEDEELSTCLMSKFTAQRLRPVYRFLSPLFQEFLAAMRLSELLGSDSQEDQDLGLYYLRQINSPLKAINSYGIFLKYVSDHCSSKAGPKVVSHLLQLVDEKESLENMSENEDYMKLHPETFLWLHFLRGLWLNSPESFSSLLSERLLNIALNFAYQSSTVAACSPVILQFLRGRTLALGVLNSQYFWDHPESLLLLGSLKVSINGNEISSHVDYS-FKTYFENLQPPAIDKEYTSAFEHISEWKRNFAEDEKIIKHYQNIWPRVLPDISEGYWKLSPKPYKIPRLEVGVNNMGPADQALLHVLMEVFSASQSIEFQLFNSSGFLESIRPALELNKTSVTKCSMSRLELSRAEQELLLTLPALQSLEVSETNQIPDQLFHNLDKFLGLKELSVRLDGTQDVLSVLPGEFPNLHHMEKLSIHTFTESDLSKLVKLIQNSPNLHDIHLKCDFLSNCESLMAALASCEKLREIEFSGRCFEAMPFVTLLPNFVFLKILNLKGQQFPDKETSEMFAQALGSLRKLEELHLPKGDGIHQVAKLIVQQCLQLPCLRVLAFHHVLDDDSVTEVARVATSRGFQKLENLDLSMNHKITEEGYRNFFQALDNLPNLQELNICRHIRECIQVQASTVKALGQCVSRLPSLTRLRMLSWLLDEEDMKVINDVKERHPQSKRLTVFWKWIVPFSPVVQE", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9JIB3-1", "uniprot_id": "BIR1G_MOUSE", "id": "Q9JIB3-1", "name": "Baculoviral IAP repeat-containing protein 1g", "aln": "--------MAEHGESSEDRISEIDYEFLAELSARFGMNLVQLAKSQEEEDHKERMKMKKGFNSQMRSEAKRLKTFESYDTFRSWTPQEMAAAGFYHTGVKLGVQCFCCSLILFGNSLRKLPIERHKKLRPECEFLQGKDVGNIGKYDIRVKSPEKMLRGGKARYHEEEARLESFEDWPFYAHGTSPRVLSAAGFVFTGKRDTVQCFSCGGSLGNWEEGDDPWKEHAKWFPKCEFLQSKKSSEEIAQYIQGYEGFVHVTGEHFVKSWVRRELPMVSAYCNDSVFANEELRMDMFKDWPQESPVGVEALVRAGFFYTGKKDIVRCFSCGGCLEKWAEGDDPMEDHIKFFPECVFLQTLKSSAEVIPTLQSQYALPEATETTRESNHGDAAAVHSTVVDLGRSEAQWFQEARSLSEQLRDTYTKTSFCHMNLPEVCSSLGTDHLLSCDVSIISKHISQPVQGALTIPEVFSNLSSVMCVEGEAGSGKTTFLKRIAFLWASGCCPLLYRFQLVFYLSLSSITPDQGLDNIICTQLLGAGGCISEVCLSSSIQQLQHQVLFLLDDYSGLASLPQALHTLITKNYLFRTCLLIAVHTNRVRDIRPYLGTSLEIQEFPFYNTVFVLRKFFSHDIICVEKLIIYFSENKDLQGVYKTPLFVAAVCNDWNQNASAQDDFQDVTLFHSYMQYLSLKYKATAESLQATVSSCGQLALTGLFSSCFEFNSDDLAEAGVDEDVKLTTFLMSKFTAQRLRPVYRFLGPLFQEFLAAVRLTELLSSDRQEDQDLGLYYLRQIDSPLKAINSFNIFLYYVSSHSSSKAAPTVVSHLLQLVDEKESLENMSENEDYMKLHPQTFLWFQFVRGLWLVSPESFSSFVSEHLLRLALIFAYESNTVAECSPFILQFLRGRTLALRVLNLEYFWDHPESLLLLRSLKVSINGNKMSSYVDYS-FKTYFENLQPPAINEEYTSAFEHVSEWRRNFAQDEEIIKNYENIWPRALPDISEGYWNLSPKPCKIPKLEVQVNNMGPADQALLQVLMEVFSASQSIEFHLFNSSGFLESIRPALELSKASVTKCSMSRLELSRAEQELLLTLPALQSLEVSETNQLPDQLFHNLHKFLGLKELCVRLDGKPDVLSVLPEEFLNLHHMEKLSIRTSTESDLSKLVKFIQNFPNLHVFHLKCDFLSNCESLMTALASCKKLREIEFSGQCFEAMTFVNILPNFVSLKILSLKGQQFADKETSEKFAQALGSLRNLEELLVPTGDGIHQVAKLIVRQCLQLPCLRVLAFHDILDDESVIEIG-AATSGSFQKLENLDISMNHKITEEGYRNFFQALDNLPNLQMLNICRNIPGRIQVQATTVKALCHCVSRLPSLTRLGMLSWLLDEEDMKVINDVKERHPQSKRLTIFWKWIVPFSPVVLE", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q13075-1", "uniprot_id": "BIRC1_HUMAN", "id": "Q13075-1", "name": "Baculoviral IAP repeat-containing protein 1", "aln": "--------MATQQKASDERISQFDHNLLPELSALLGLDAVQLAKELEEEEQKERAKMQKGYNSQMRSEAKRLKTFVTYEPYSSWIPQEMAAAGFYFTGVKSGIQCFCCSLILFGAGLTRLPIEDHKRFHPDCGFLLNKDVGNIAKYDIRVKNLKSRLRGGKMRYQEEEARLASFRNWPFYVQGISPCVLSEAGFVFTGKQDTVQCFSCGGCLGNWEEGDDPWKEHAKWFPKCEFLRSKKSSEEITQYIQSYKGFVDITGEHFVNSWVQRELPMASAYCNDSIFAYEELRLDSFKDWPRESAVGVAALAKAGLFYTGIKDIVQCFSCGGCLEKWQEGDDPLDDHTRCFPNCPFLQNMKSSAEVTPDLQSRGELCELLETTSESNLEDSIAVGPIVPEMAQGEAQWFQEAKNLNEQLRAAYTSASFRHMSLLDISSDLATDHLLGCDLSIASKHISKPVQEPLVLPEVFGNLNSVMCVEGEAGSGKTVLLKKIAFLWASGCCPLLNRFQLVFYLSLSSTRPDEGLASIICDQLLEKEGSVTEMCVRNIIQQLKNQVLFLLDDYKEICSIPQVIGKLIQKNHLSRTCLLIAVRTNRARDIRRYLETILEIKAFPFYNTVCILRKLFSHNMTRLRKFMVYFGKNQSLQKIQKTPLFVAAICAHWFQYPFDPS-FDDVAVFKSYMERLSLRNKATAEILKATVSSCGELALKGFFSCCFEFNDDDLAEAGVDEDEDLTMCLMSKFTAQRLRPFYRFLSPAFQEFLAGMRLIELLDSDRQEHQDLGLYHLKQINSPMMTVSAYNNFLNYVSSLPSTKAGPKIVSHLLHLVDNKESLENISENDDYLKHQPEISLQMQLLRGLWQICPQAYFSMVSEHLLVLALKTAYQSNTVAACSPFVLQFLQGRTLTLGALNLQYFFDHPESLSLLRSIHFPIRGNKTSPRAHFSVLETCFDKSQVPTIDQDYASAFEPMNEWERNLAEKEDNVKSYMDMQRRASPDLSTGYWKLSPKQYKIPCLEVDVNDIDVVGQDMLEILMTVFSASQRIELHLNHSRGFIESIRPALELSKASVTKCSISKLELSAAEQELLLTLPSLESLEVSGTIQSQDQIFPNLDKFLCLKELSVDLEGNINVFSVIPEEFPNFHHMEKLLIQISAEYDPSKLVKLIQNSPNLHVFHLKCNFFSDFGSLMTMLVSCKKLTEIKFSDSFFQAVPFVASLPNFISLKILNLEGQQFPDEETSEKFAYILGSLSNLEELILPTGDGIYRVAKLIIQQCQQLHCLRVLSFFKTLNDDSVVEIAKVAISGGFQKLENLKLSINHKITEEGYRNFFQALDNMPNLQELDISRHFTECIKAQATTVKSLSQCVLRLPRLIRLNMLSWLLDADDIALLNVMKERHPQSKYLTILQKWILPFSPIIQK", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ** : ::*::::*::* : *.**** :*:: ***.*. ***::*** **:**:*:************ :*:.: ** **********.***: *:*********** .* ::*** *::::*:* ** .******.*******. :. ***: **:****** **.:****.:* ** *** ********:**********.************************:****:*** ****.* **:.::*****:***:****:.***.***:** * **:* *****:**.*.* **.:**:**** ****:*******:*:* *****::** : **:* ***.:****** * ***: * *** *** *. ** . * :.:.**** ***:.*.**** :**.:** **.* : *.*.*****.*:: : ***:*:*** .*.:****.**.**************.:**:************* ********** * .*:** .*** *** *.::*:.: . **:*::*********. : *:**.: .** **:* *****:**:***.**** ** * *:*: ******: :***:***: : ::::**..*:.** : ********:* .* * . *:**::*:***: * *: **** *:*******.***.*:**..***..*** ******* .*: ************.****.* ******.:** ***.** **.******:*:**:**: ::.::. ** ***. *:**.*.:*****:***:******:***:**:* :*: * ::::**** .*::: *::**:** :** **:*.*** ***.:****:****:* .** :**:****** ** *::..*.**: *. ..:* ::* *:: * *:*:::*:**** :.**.**:*:.*. :* * :: *. **:* ***:**** *** *** **::. ..* :*.:** ****** **::* :* **:*********.*:******:*:**** **********:*:***** * * **:* **.*** ****.* *:*. :*:**:* ** *:****** *: :* * *****:*** **** :****:*:*: ***: *.**:** **:**. *:*:.** ****: ****.*:****.*:**** ** **** :**** :*.****::*****::** ** *****:*.. *:*:** *:. .* * .*******.:*:******************:**** *:*.*:: *:.**:***:* :** *** * ** ******* :*: ::* :******** **:: ***:****:: :", "identical_positions": 863, "similar_positions": 335, "identity": "61.12%" }, { "cls_id": "homologset.agr.MGI:1858257", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZAA9-1", "uniprot_id": "MPP2_RAT", "id": "D3ZAA9-1", "name": "MAGUK p55 subfamily member 2", "aln": "MP--------------VAATNSESAMQQVLDNLG--SLPNATGAAELDLIFLRGIMESPIVRSLAK------------------------AHERLEETKLEAVRDNNLELVQEILRDLAELAEQSSTAAELARILQEPHFQSLLETHDSVASKTYETPPPSPG--LDPTFSNQ---------------PVPPDAVRMVGIRKTAGEHLGVTFRVEG-GELVIARILHGGMVAQQGLLHVGDIIKEVNGQPVGSDPRALQELLRSASGSVILKILPSYQEPHLPR-----------------------QVFVKCHFDYDPARDSLIPCKEAGLRFNAGDLLQIVNQDDANWWQACHVEGGS--AGLIPSQLLEEKRKAFVKRDLELTPTSGTLCGSLSGKKKKRMMYLTTKNAEFDRHELLIYEEVARMPPFRRKTLVLIGAQGVGRRSLKNKLILWDPDRYGTTVPYTSRRPKDSEREGQGYSFVSRGEMEADIRAGRYLEHGEYEGNLYGTRIDSIRGVVASGKVCVLDVNPQAVKVLR-TAEFVPYVVFIEAPDFETLRAMNRAALESG------------------------VSTKQLTEADLRRTVEESSRIQRGYGHYFDLSLVNSNLERTFRELQTAMEKLRTEPQWVPVSWVY", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9WV34-1", "uniprot_id": "MPP2_MOUSE", "id": "Q9WV34-1", "name": "MAGUK p55 subfamily member 2", "aln": "MP--------------VAATNSESAMQQVLDNLG--SLPNATGAAELDLIFLRGIMESPIVRSLAK------------------------AHERLEETKLEAVRDNNLELVQEILRDLAELAEQSSTAAELARILQEPHFQSLLETHDSVASKTYETPPPSPG--LDPTFSNQ---------------PVPPDAVRMVGIRKTAGEHLGVTFRVEG-GELVIARILHGGMVAQQGLLHVGDIIKEVNGQPVGSDPRALQELLRSASGSVILKILPSYQEPHLPR-----------------------QVFVKCHFDYDPARDSLSPCKEAGLRFNAGDLLQIVNQDDANWWQACHVEGGS--AGLIPSQLLEEKRKAFVKRDLELTPTSGTLCGSLSGKKKKRMMYLTTKNAEFDRHELLIYEEVARMPPFRRKTLVLIGAQGVGRRSLKNKLILWDPDRYGTTVPYTSRRPKDSEREGQGYSFVSRGEMEADIRAGRYLEHGEYEGNLYGTRIDSIRGVVASGKVCVLDVNPQAVKVLR-TAEFVPYVVFIEAPDYETLRAMNRAALESG------------------------VSTKQLTEADLRRTVEESSRIQRGYGHYFDLSLVNSNLERTFRELQTAMEKLRTEPQWVPVSWVY", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q14168-1", "uniprot_id": "MPP2_HUMAN", "id": "Q14168-1", "name": "MAGUK p55 subfamily member 2", "aln": "MP--------------VAATNSETAMQQVLDNLG--SLPSATGAAELDLIFLRGIMESPIVRSLAKVIMVLWFMQQNVFVPMKYMLKYFGAHERLEETKLEAVRDNNLELVQEILRDLAHVAEQSSTAAELAHILQEPHFQSLLETHDSVASKTYETPPPSPG--LDPTFSNQ---------------PVPPDAVRMVGIRKTAGEHLGVTFRVEG-GELVIARILHGGMVAQQGLLHVGDIIKEVNGQPVGSDPRALQELLRNASGSVILKILPSYQEPHLPR-----------------------QVFVKCHFDYDPARDSLIPCKEAGLRFNAGDLLQIVNQDDANWWQACHVEGGS--AGLIPSQLLEEKRKAFVKRDLELTPNSGTLCGSLSGKKKKRMMYLTTKNAEFDRHELLIYEEVARMPPFRRKTLVLIGAQGVGRRSLKNKLIMWDPDRYGTTVPYTSRRPKDSEREGQGYSFVSRGEMEADVRAGRYLEHGEYEGNLYGTRIDSIRGVVAAGKVCVLDVNPQAVKVLR-TAEFVPYVVFIEAPDFETLRAMNRAALESG------------------------ISTKQLTEADLRRTVEESSRIQRGYGHYFDLCLVNSNLERTFRELQTAMEKLRTEPQWVPVSWVY", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M2B2Q1-1", "uniprot_id": "A0A8M2B2Q1_DANRE", "id": "A0A8M2B2Q1-1", "name": "", "aln": "MAGSLYNRLSLEEIGSIRSLESPGAMQSLLDTLS--DSTSSTTANDLDLIFLKGIMESPVSR------------------------------EHYEEPKLEAVRDNNVELVQDILRDLNTLSPDSPAAHELICILKEPHFQSLLETHDSVASKSYETPPPSPCAFMDPAFNNQ---------------PVPPDAVRMVGIRKVSGEHLGVTFRVEG-GELVIARILHGGMIDQQGLLHVGDIIKEVNGKEVGSDPKVLQNMLKESSGSVVLKILPSYQEPHTPR-----------------------QAFVKCHFDYDPSHDNLIPCKEAGLKFSSGDILQIFNQEDPNWWQACHLEGGS--AGLIPSQLLEEKRKAFVKRDLELAS-TGPLCAGIGGKKKKKMMYLTTKNAEFDRHELRIYEEVARVPPFRRKTLVLIGAQGVGRRSLKNKLLVSDPHRYGTTTPYTSRKPKVDEKEGQMYLFMSRSEMETDIKCGRFLEHGEYDGNLYGTKIDSIHEVVDSGKICILDVNPQALKVLR-TAEFLPYVVFIEAPNFEVLKDMNRSAIEAG------------------------VVTKQMTDSELKRTVDESERIQRAYSHYFDLSIVNDNLDGAYRSLRRALDRLNTDQQWVPVSWVF", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q7KT16-1", "uniprot_id": "Q7KT16_DROME", "id": "Q7KT16-1", "name": "", "aln": "MVRWSARSRRQARQDKVELLARNNKVNGEDDTSDNAAFRNSTDLSDHDEIFLKGLLRSNSNTPHKELMLN--------------------PTEPQPVPLFLPAHLNNKPICDDIIRKFSPS--RRLESRELAKLLAQPHFRALLRAHDEIGALYEQRLKAAGGSTSQLEIASQRQTGGYLFTEDVLNTKMPVETIKMVGLRRDPSKPLGLTVELDEFKQLVVARILAGGVIDKQSMLHVGDVILEVNGTPVRT-PDELQVEVSRAKENLTLKIGPNVDEEIKSGRYTVSGGQVKQNGIASLETGKKLTCYMRALFTYNPSEDSLLPCRDIGLPFKSGDILQIINVKDPNWWQAKNITAESDKIGLIPSQELEERRKAFVAPEADYVHKIG-ICGTRISKRKRKTMYRSVANCEFDKAELLLYEEVTRMPPFRRKTLVLIGVSGVGRRTLKNRLINSDVDKFGAVIPHTSRPKRALEENGSSYWFMDREEMEEAVRNNEFLEYGEHNGNLYGTHLQSIKDVINSGRMCILDCAPNALKILHNSQELMPFVIFVAAPGMEQLKTIYADRRATGSNRNLSFDRQSSIRFSSRRARTLESLASLYEDDDLVATVEESSFVQRKYEKYFDMVIVNEDFDETFRQVVETLDQMSHEEQWVPVNWIY", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* : :: *. . .:* : * ***:*::.* * . : ..: ** : ::*:*.: : ** :* :***::**.:**.:.: : .: : : .* :* ::::***:*: ..: **:*..:: :**:**** **:: :*.:*****:* **** * : * ** : :. .: *** *. :* . :::. * *:*:.*.* **:: ** *.:**:***.* .*.***** :: . * ****** ***:***** : : . * :*. .*:*:: ** :. *.***: ** :****:*:************..*****:***:*: * .::*:. *:*** : *.:*. * *:.* *** :: ..:**:**::******:::**: *: :*::*:** *:*:*:*: : *::*:*:*: **. * *: : :* :. : :* **:**. :** * :***: :**.::: ::*.: ::::: : *****.*::", "identical_positions": 200, "similar_positions": 183, "identity": "30.3%" }, { "cls_id": "homologset.agr.MGI:1858258", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9Z1D1-1", "uniprot_id": "EIF3G_MOUSE", "id": "Q9Z1D1-1", "name": "Eukaryotic translation initiation factor 3 subunit G", "aln": "MPTGDFD-SKPSWADQVEEEGEDDKCVTSELLKGIPLPTGDTSPEPELLPGDPLPPPKEVINGNIKTVTEYKIEEDGKKFKIVRTFRIETRKASKAVARRKNWKKFGNSEFDPPGPNVATTTVSDDVSMTFITSKEDLNCQE-EEDPMNKLKGQKIVSCRICKGDHWTTRCPYKDTLGPMQKELAEQLGLSTGEKEKLPGELEPVQAAQSKTGKYVPPSLRDGAS-RRGESMQPNRRADDNATIRVTNLSEDTRETDL-QELFRPFGSISRIYLAKDKTTGQSKGFAFISFHRREDAARAIAGVSGFGYDHLILNVEWAKPSTN-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q5RK09-1", "uniprot_id": "EIF3G_RAT", "id": "Q5RK09-1", "name": "Eukaryotic translation initiation factor 3 subunit G", "aln": "MPTGDFD-SKPSWADQVEEEGEDDKCVTSELLKGIPLPTGDTSPEPELLPGDPLPPPKEVINGNIKTVTEYKVEEDGKKFKIVRTFRIETRKASKAVARRKNWKKFGNSEFDPPGPNVATTTVSDDVSMTFITSKEDLNCQE-EEDPMNKLKGQKIVSCRICKGDHWTTRCPYKDTLGPMQKELAEQLGLSTGEKEKLPGELEPVQAAQNKTGKYVPPSLRDGAS-RRGESMQPNRRADDNATIRVTNLSEDTRETDL-QELFRPFGSISRIYLAKDKTTGQSKGFAFISFHRREDAARAIAGVSGFGYDHLILNVEWAKPSTN-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O75821-1", "uniprot_id": "EIF3G_HUMAN", "id": "O75821-1", "name": "Eukaryotic translation initiation factor 3 subunit G", "aln": "MPTGDFD-SKPSWADQVEEEGEDDKCVTSELLKGIPLATGDTSPEPELLPGAPLPPPKEVINGNIKTVTEYKIDEDGKKFKIVRTFRIETRKASKAVARRKNWKKFGNSEFDPPGPNVATTTVSDDVSMTFITSKEDLNCQE-EEDPMNKLKGQKIVSCRICKGDHWTTRCPYKDTLGPMQKELAEQLGLSTGEKEKLPGELEPVQATQNKTGKYVPPSLRDGAS-RRGESMQPNRRADDNATIRVTNLSEDTRETDL-QELFRPFGSISRIYLAKDKTTGQSKGFAFISFHRREDAARAIAGVSGFGYDHLILNVEWAKPSTN-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6DRC4-1", "uniprot_id": "EIF3G_DANRE", "id": "Q6DRC4-1", "name": "Eukaryotic translation initiation factor 3 subunit G", "aln": "MPSIEFDDSKPSWADQVEEEGDE----------------------------GSLPSPKETVKGNIKTVTEYKIDDDGQKFKIIRTFKIETRKASKAVARRKNWKKFGNSEYDAPGPNVATTTVSDDVFMTFISSKEDLNAQDQDEDPMNKLKGQKIVSCRICKGDHWTTRCPYKDTLGPMQKELAEQLGLSTGEKEK-AAEPEPAQPVQNKTGKYVPPSLRDGGT-RRGESMQPNRRADDNATIRVTNLSEDTRETDL-QELFRPFGSISRIYLAKDKNTGQSKGFAFISFHRREDAARAIAGVSGFGYDHLILNVEWAKPSNN-", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9W4X7-1", "uniprot_id": "EI3G1_DROME", "id": "Q9W4X7-1", "name": "Eukaryotic translation initiation factor 3 subunit G-1", "aln": "--MPGVETIKSSWADEVELDYG------------------------------GLPPTTETVENGQKYVTEYKYNKDDKKTKVVRTYKISKQVVPKTVAKRRTWTKFGDSKNDKPGPNSQTTMVSEEIIMQFLNSKEDEKANDPLLDPT-----KNIAKCRICNGEHWSVNCPYKGTA----------MDTN-MMEKKASAAAAAAVDAP-KSGKYVPPFLKD----SQKGALG-MRGRDDTAAIRISNLSESMTEADL-EELVKKIGPQSKMYLARDKNTGLCKGFAYVHFKQRKDAAAAIEILNGHGYDHLILSVEWSKPQNN-", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VDM6-1", "uniprot_id": "EI3G2_DROME", "id": "Q9VDM6-1", "name": "Eukaryotic translation initiation factor 3 subunit G-2", "aln": "-----MKTFVTSWADEVDADYVD-----------------------------GLPPSNEYIKGDFKYVTEYKFNDDGKKVKVVRTFKIEKQIVPKAVARRRNWVKFGDSRSDKPGPNSQTTMASEEIFMQFIGSKDFDQTHETQLDPG-----KNIAKCRICNGEHWSVNCPYKGTS----------MDSKTVMETKANAAAAAAISDPSKTGKYVPPFMKDGGGISGSKNWGRGRDRDDSSAVRISNLSESMTETDL-EELVKKIGPHTKMYLAREKNSGLCKGFAYVHFKFRQDAAAAIEVLNGHGYDHLILCVEWSKPQP--", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q04067-1", "uniprot_id": "EIF3G_YEAST", "id": "Q04067-1", "name": "Eukaryotic translation initiation factor 3 subunit G", "aln": "----MSEVAPEEIIENAD-------------------------------------GSRSIITYKIEDGVKYKITQKVKEVKVL-------EKVHKSVAERKNWHKYGSEKGSPAGPSAVTARLGEEVELRLS--RNWKQAEEERIQKEKASLTKTGLQCRLCGNDHMTMNCPFKTILSELS-ALEDPATNEGGVEAASEEKAGQVGGAGSIPGQYVPPSRRAGARDPSSDAYRDSRERDDMCTLKIMQVNENADENSLREELLFPFAPIPRVSVVRNKETGKSRGLAFVTFSSEEVAEQALRFLDGRGYMNLILRVEWSKPKVKE", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . . ::.: . . : : .:** .. :: *:: . . *:**.*:.* *:*... . .**. *: .::: : : :: : .: : :. .**:* .:* : .**:* . : . .*:**** : * ** .:::: ::.*. * .* :**. :.. .:: :.::* :* .:*:*:: * .: * *: :.* ** :*** ***:**. ", "identical_positions": 51, "similar_positions": 95, "identity": "15.69%" }, { "cls_id": "homologset.agr.MGI:1858259", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9QYA2-1", "uniprot_id": "TOM40_MOUSE", "id": "Q9QYA2-1", "name": "Mitochondrial import receptor subunit TOM40 homolog", "aln": "MGNVLAASSPPAGPPPPPTPSLVGLPPPPPSPPGFTLPPLGGGLGTGSSTGRGSERTPGAAASGAAAASEDGSCGCLPNPGTFEECHRKCK---ELFPVQMEGVKLTVNKGLSN--RFQVTHTVALGTIGESNYHFGVTYVGTKQLSPTEAFPVLVGDMDNSGSLNAQVIHQLSPGLRSKMAIQTQQSKFVNWQVDGEYRGSDFTAAVTLGNPDVLVG---SGILVAHYLQSITPCLALGGELVYHRRP---GEEGTVMSLAGKYTLN--NWLATVTLGQ-AGMHATYYHKASDQLQVGVEFEASTRMQ-----------------DTSASFGYQLDLPKANFLFKGSVNSNWIVGATLEKKLPPLPLTLSLCAFLNHRKNKFLCGFGLTIG---------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q75Q40-1", "uniprot_id": "TOM40_RAT", "id": "Q75Q40-1", "name": "Mitochondrial import receptor subunit TOM40 homolog", "aln": "MGNVLAASSPPAGPPPPPTPSLVGLPPPPPSPPGFTLPPLGGGLGTGSNAGRGSERTPGAAASGAAASSNDGNCGCLPNPGTFEECHRKCK---ELFPVQMEGVKLTVNKGLSN--RFQVTHTVALGTIGESNYHFGVTYVGTKQLSPTEAFPVLVGDMDNSGSLNAQVIHQLSPGLRSKMAIQTQQSKFVNWQVDGEYRGSDFTAAVTLGNPDVLVG---SGILVAHYLQSITPCLALGGELVYHRRP---GEKGTVMSLAGKYTLN--NWLATVTLGQ-AGMHATYYHKASDQLQVGVEFEASTRMQ-----------------DTSASFGYQLDLPKANFLFKGSVNSNWIVGATLEKKLPPLPLTLSLCAFLNHRKNKFLCGFGLTIG---------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O96008-1", "uniprot_id": "TOM40_HUMAN", "id": "O96008-1", "name": "Mitochondrial import receptor subunit TOM40 homolog", "aln": "MGNVLAASSPPAGPPPPPAPALVGLPPPPPSPPGFTLPPLGGSLGAGTSTSRSSERTPGAATASASGAAEDGACGCLPNPGTFEECHRKCK---ELFPIQMEGVKLTVNKGLSN--HFQVNHTVALSTIGESNYHFGVTYVGTKQLSPTEAFPVLVGDMDNSGSLNAQVIHQLGPGLRSKMAIQTQQSKFVNWQVDGEYRGSDFTAAVTLGNPDVLVG---SGILVAHYLQSITPCLALGGELVYHRRP---GEEGTVMSLAGKYTLN--NWLATVTLGQ-AGMHATYYHKASDQLQVGVEFEASTRMQ-----------------DTSVSFGYQLDLPKANLLFKGSVDSNWIVGATLEKKLPPLPLTLALGAFLNHRKNKFQCGFGLTIG---------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M6Z1R1-1", "uniprot_id": "A0A8M6Z1R1_DANRE", "id": "A0A8M6Z1R1-1", "name": "", "aln": "MRRESSSSCWYTSFLTMGSVLAASSPNPPPASGGGTAP-AGAGLVTVPPGFTMPPVSGVPPSSGTQGQPGTDSESSLPNPGTFEECHRKCK---EVFPVQMEGVRLVVNKGLSN--HFQVSHTITLSTLGDSGYRFGSTYVGSKQTGPAESFPVMVGDMDNTGSLNAQVIHQLTNRVRSKIAIQTQQHKFVNWQCDGEYRGDDFTAAVTLGNPDVLVG---SGILVAHYLQSLSPSLVLGGELVYHKRP---GEEGTVTSLVGRYTGS--NYVATLTVGG-AGAHASYYHKANDQLQVGVEFEASTRMQ-----------------ETSVSFGYQLDVPKANLLFKGSLDSNWVVGATLEKKLLPLPLSLALGAFLNHRKNKFQCGFGVTIG---------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9U4L6-1", "uniprot_id": "TO401_DROME", "id": "Q9U4L6-1", "name": "Mitochondrial import receptor subunit TOM40 homolog 1", "aln": "MGNVLAASSGAPGS--GASNLGLGLQEPAPLPSN------SGSLTESSSSAEGLDSLAAAKDA------------ALENPGTVEELHKKCK---DIQAITFEGAKIMLNKGLSN--HFQVSHTINMSNVVPSGYRFGATYVGTKEFSPTEAFPVLLGDIDPAGNLNANVIHQFSARLRCKFASQIQESKVVASQLTTDYRGSDYTLSLTVANPSIFTN---SGVVVGQYLQSVTPALALGSELAYQFGPNVPGRQIAIMSVVGRYTAG--SSVWSGTLGQ-SGLHVCYYQKASDQLQIGAEVETSLRMQ-----------------ESVATLAYQIDLPKANLVFRGGIDSNWQIFGVLEKRLAPLPFTLALSGRMNHVKNNFRLGCGLMIG---------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "A1Z6L1-1", "uniprot_id": "TO402_DROME", "id": "A1Z6L1-1", "name": "Mitochondrial import receptor subunit TOM40 homolog 2", "aln": "MGNVMASTADAESSR-GRGHLSAGLRLP-EAPQY------SGGVP--PQMVEALK--AEAKKP------------ELTNPGTLEELHSRCR---DIQANTFEGAKIMVNKGLSN--HFQVTHTINMNSAGPSGYRFGATYVGTKQYGPTEAFPVLLGEIDPMGNLNANVIHQLTSRLRCKFASQFQDSKLVGTQLTGDYRGRDYTLTLTMGNPGFFTS---SGVFVCQYLQSVTKRLALGSEFAYHYGPNVPGRQVAVLSAVGRYAFG--DTVWSCTLGP-AGFHLSYYQKASDQLQIGVEVETNIRQQ-----------------ESTATVAYQIDLPKADLVFRGSLDSNWLISGVLEKRLQPLPFSLAISGRMNHQKNSFRLGCGLMIG---------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P23644-1", "uniprot_id": "TOM40_YEAST", "id": "P23644-1", "name": "Mitochondrial import receptor subunit TOM40", "aln": "----MSAPTPLAEASQIPTIPALSPLTAKQSKGN-----FFSSNPISSFVVDTYKQLHSHRQS-----------LELVNPGTVENLNKEVSRDVFLSQYFFTGLRADLNKAFSMNPAFQTSHTFSIGSQALPKYAFSALFANDN--------LFAQGNIDNDLSVSGRLNYGWDKKNISKVNLQISDGQPTMCQLEQDYQASDFSVNVKTLNPSFSEKGEFTGVAVASFLQSVTPQLALGLETLYSRTDG-SAPGDAGVSYLTRYVSKKQDWIFSGQLQANGALIASLWRKVAQNVEAGIETTLQAGMVPITDPLMGTPIGIQPTVEGSTTIGAKYEYRQS--VYRGTLDSNGKVACFLERKVLPT-LSVLFCGEIDHFKNDTKIGCGLQFETAGNQELLMLQQGLDADGNPLQALPQL", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ::. . . .. . . * ****.*: : . : : * : :**.:* **..**. :.. . * *. :.. : . *::* .:...: : .*. * .: : . * :*:. *:: :. **.. :*: * :***:: *.** * * . : * :*. . : : : .. ::*. :::: * * . : .:.. : : :: :::* ::** : **::: * ::: : . ::* **. * *: : ", "identical_positions": 51, "similar_positions": 108, "identity": "12.17%" }, { "cls_id": "homologset.agr.MGI:1858260", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q62931-1", "uniprot_id": "GOSR1_RAT", "id": "Q62931-1", "name": "Golgi SNAP receptor complex member 1", "aln": "MAAGTSNYWEDLRKQARQLENELDLKLVSFSKLCTSYSHSSARDGGRDRYSSDTTPLLNGSSQDRMFETMAIEIEQLLARLTGVNDKMAEYTHSAGVPSLNAALMHTLQRHRDILQDYTHEFHKTKANFMAIRERENLM-GSVRKDIESYKSGSGVNNRRTELFLKEHDHLRNSDRLIEETISIAMATKENMTSQRGMLKSIHSKMNTLANRFPAVNSLIQRINLRKRRDSLILGGVIGICTILLLLYAFH", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O88630-1", "uniprot_id": "GOSR1_MOUSE", "id": "O88630-1", "name": "Golgi SNAP receptor complex member 1", "aln": "MAAGTSNYWEDLRKQARQLENELDLKLVSFSKLCTSYSHSGSRDGGRDRYSSDTTPLLNGSSQDRMFETMAIEIEQLLARLTGVNDKMAEYTHSAGVPSLNAALMHTLQRHRDILQDYTHEFHKTKANFTAIRERENLM-GSVRKDIESYKSGSGVNNRRTELFLKEHDHLRNSDRLIEETISIAMATKENMTSQRGMLKSIHSKMNTLANRFPAVNSLIQRINLRKRRDSLILGGVIGICTILLLLYAFH", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O95249-1", "uniprot_id": "GOSR1_HUMAN", "id": "O95249-1", "name": "Golgi SNAP receptor complex member 1", "aln": "MAAGTSSYWEDLRKQARQLENELDLKLVSFSKLCTSYSHSSTRDGRRDRYSSDTTPLLNGSSQDRMFETMAIEIEQLLARLTGVNDKMAEYTNSAGVPSLNAALMHTLQRHRDILQDYTHEFHKTKANFMAIRERENLM-GSVRKDIESYKSGSGVNNRRTELFLKEHDHLRNSDRLIEETISIAMATKENMTSQRGMLKSIHSKMNTLANRFPAVNSLIQRINLRKRRDSLILGGVIGICTILLLLYAFH", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "E9QFW9-1", "uniprot_id": "E9QFW9_DANRE", "id": "E9QFW9-1", "name": "Golgi SNAP receptor complex member 1", "aln": "MAGGNSNYWEDLRKQARQLENELDLKLVSFSKLCTSYSSS--RDGRRGDSSSDTTPLLCNSTQDRMFETMSVEIEQLLAKLTGVNDKMAEYTSTPGVTSLNAALMHTLQRHRDILQDYTHEFHKTKSNFMAIREREDLL-GSVRKDIETYKSGSGVNNRRTELFLKEHEHLRNSDRLIDDTISIAMATKENMTSQRGLLKSIQSRVNTLANRFPAINNLIQRINLRKRRDSLILGGVIGICTILLLLYAFH", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VE50-1", "uniprot_id": "GOSR1_DROME", "id": "Q9VE50-1", "name": "Golgi SNAP receptor complex member 1", "aln": "-MGGSS--YDVLRKQARSLENEIDLKLVAFSKIGAGSGGG----GSGGLGGVDTSPLLG----EHVFDSLSEEIEQMLEKLSSLNESMSDLPASG------AAAMHTLQRHREILQGYRQEFNKICANHTMRIEREELLRGSGLATSSGSPSISGLNRR--EMYLKESGHLNSASHLVNDQINIAIETRDHLHAQRQAFKRLQTRFNDISNRFPLISSLIQRINIKKRRDSLILGAVIGFCVILLLLYAFN", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P38736-1", "uniprot_id": "GOSR1_YEAST", "id": "P38736-1", "name": "Golgi SNAP receptor complex member 1", "aln": "--MSSQPSFVTIRGKAISLETQTESLLSKYSTFAQTTSSE----------------------QTGQEKKIDKQLEGILGQRQDVIDSLTQICDSN--PAISASKLSQLHRHKEILQDHWKSFRNIRSSIQQERNRLNLLFSVKNDIANSTTDAPAPIGDADEYIQNETRRIDQSNNVVDRLISQAWETRSQFHSQSNVLNTANNKVLQTLQRIPGVNQLIMKINTRRKKNAFVLATITTLCILFLFFTW--", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ... : :* :* .**.: : * :*.: . ..: ::* :* : .: :.::: : *: : *:**::***.: :.*.: :. :* :*: . . . .. * :* :: .:..::: *. * *:.:: :* :: :.:. :*:* :..** :** ::::::::*. : :* ::*:: ", "identical_positions": 33, "similar_positions": 93, "identity": "13.15%" }, { "cls_id": "homologset.agr.MGI:1858261", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P63116-1", "uniprot_id": "AAA1_RAT", "id": "P63116-1", "name": "Asc-type amino acid transporter 1", "aln": "------------------MRRDSDMASHIQQPGGHGNPGPAP-SPSPGPGPGPGASERVALKKEIGLVSACTIIIGNIIGSGIFISPKGVLEHSG-SVGLALFVWVLGGGVTALGSLCYAELGVAIPKSGGDYAYVTEIFGGLAGFLLLWSAVLIMYPTSLAVISMTFSNYVLQPVFPNCIPPATASRVLSMACLMLLTWVNSSSVRWATRIQVIFTGGKLLALSLIITVGFVQIFQGHFEELRPT----NAFAFWMTPSVGHLALAFLQGSFAFSGWNFLNYVTEELVDPRKNLPRAIFISIPLVTFVYTFTNVAYFTAMSPQELLSS-NAVAVTFGEKLLG--YFSWVMPVSVALSTFGGINGYLFTSSRLCFSGAREGHLPSFLAMIHVRRCTP----IPALLVCCGATAVIMLV-GDTYTLIN-YVSFINYLCYGVTILGLLVLRWRRP----ALHRPIKVNLLVPVVYLVFWAFLLVFSFISEP------------MVCGVGIIIILTGVPIFFLGVFWRSKP---KCVHRFTESMTRWGQELCFVVYPQGSLEEEENGPMGQPSPLPITDKPLKTQ--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P63115-1", "uniprot_id": "AAA1_MOUSE", "id": "P63115-1", "name": "Asc-type amino acid transporter 1", "aln": "------------------MRRDSDMASHIQQPGGHGNPGPAP-SPSPGPGPGPGASERVALKKEIGLVSACTIIIGNIIGSGIFISPKGVLEHSG-SVGLALFVWVLGGGVTALGSLCYAELGVAIPKSGGDYAYVTEIFGGLAGFLLLWSAVLIMYPTSLAVISMTFSNYVLQPVFPNCIPPATASRVLSMACLMLLTWVNSSSVRWATRIQVIFTGGKLLALSLIITVGFVQIFQGHFEELRPT----NAFAFWMTPSVGHLALAFLQGSFAFSGWNFLNYVTEELVDPRKNLPRAIFISIPLVTFVYTFTNVAYFTAMSPQELLSS-NAVAVTFGEKLLG--YFSWVMPVSVALSTFGGINGYLFTSSRLCFSGAREGHLPSFLAMIHVRRCTP----IPALLVCCGATAVIMLV-GDTYTLIN-YVSFINYLCYGVTILGLLVLRWRRP----ALHRPIKVNLLVPVVYLVFWAFLLVFSFISEP------------MVCGVGIIIILTGVPIFFLGVFWRSKP---KCVHRFTESMTRWGQELCFVVYPQGSLEEEENGPMGQPSPLPITDKPLKTQ--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9NS82-1", "uniprot_id": "AAA1_HUMAN", "id": "Q9NS82-1", "name": "Asc-type amino acid transporter 1", "aln": "------------------------MAGHTQQPSGRGNPRPAP-SPSPVPGTVPGASERVALKKEIGLLSACTIIIGNIIGSGIFISPKGVLEHSG-SVGLALFVWVLGGGVTALGSLCYAELGVAIPKSGGDYAYVTEIFGGLAGFLLLWSAVLIMYPTSLAVISMTFSNYVLQPVFPNCIPPTTASRVLSMACLMLLTWVNSSSVRWATRIQDMFTGGKLLALSLIIGVGLLQIFQGHFEELRPS----NAFAFWMTPSVGHLALAFLQGSFAFSGWNFLNYVTEEMVDARKNLPRAIFISIPLVTFVYTFTNIAYFTAMSPQELLSS-NAVAVTFGEKLLG--YFSWVMPVSVALSTFGGINGYLFTYSRLCFSGAREGHLPSLLAMIHVRHCTP----IPALLVCCGATAVIMLV-GDTYTLIN-YVSFINYLCYGVTILGLLLLRWRRP----ALHRPIKVNLLIPVAYLVFWAFLLVFSFISEP------------MVCGVGVIIILTGVPIFFLGVFWRSKP---KCVHRLTESMTHWGQELCFVVYPQDAPEEEENGPCP-PSLLPATDKPSKPQ--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "E7FE11-1", "uniprot_id": "E7FE11_DANRE", "id": "E7FE11-1", "name": "", "aln": "-------------------------MDGVERKKTEARRSIMK-DSELKR--DSGIPERVTLKKEIGLLSACTIIIGNIIGSGIFISPKGVLEHSG-SVGLALVVWMLGGGVAALGSLCYAELGVTIPKSGGDYSYVTEIFGGLVGFLLLWSAVLIMYPTTLAVIALTFSSYVLQPVFPHCVPPYIATRMLSAICILFLTWVNCYSVRLATRIQDAFTVGKLLALGLIITVGLVQICGGNYESLTPQ----TAFTFNKAPSIGQIALAFLHASFAFSGWNFLNYVTEEVVDPRRNLPRAIYISIPLVTCVYTLTNIAYFSSMSPEELLSS-NAVAVTFGEKLLG--MFSTLMPISVALSTFGGINGYLFTSSRLCFSGAREGHLPSLLAMIHFKHCTP----IPALLVCCTATIVILCI-GETHNLIN-YVSFINYLSYGVTIAGLLYYRWKKP----NLYRPIKVSLLVPVCYLLFWALLLAFSLHSEP------------LVCGVGLVIMLTGVPVYFLGVYWKDKP---RCIYDFTEWATYLGQRVFFVVFPQI--DPIELAEWTDKSSFTSKSSGHL----", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "G8JL19-1", "uniprot_id": "G8JL19_DANRE", "id": "G8JL19-1", "name": "", "aln": "-------------------------MDGTETNRRNCAKSEQQ-KMLDSRGNQSGSKDRVTLKKEIGLLSACAIIIGNIIGSGIFISPKGVLDHAG-SVGFSLIVWVLGGGICALGSLCYAELGVTIPKSGGDYSYVTEIFGGLVGFLLLWSAVLIMYPTTLAVIALTFSNYVLQPAFPNCLPPYIATRLLSTTCVLFLTWVNCSSVRWGTRIQDVFTVGKLLALVLIIVVGMVQIAKGHYDALEPQ----AAFEFIKDPSVGQIALAFLQASFAYSGWNFLNYVTEEVVEPRKNLPRAIYISIPLVTLVYTLTNIAYFSSMSPQELLES-NAVAVTFGEKLLG--MFSWVMPISVALSTFGGINGYLFTSSRLCFSGAREGHLPYLLAMIHLKSCTP----IPALIVCCTATIVILCI-GDTHNLIN-YVSFINYLSYGVTIAGLLYYRWKKP----NMFRPIKVNLLVPCSYLVFWAVLLGFSLYSEP------------VVCGMGLVIMLTGVPIYFIGVQWKNKP---QWIYSAIERVTYLGQKMCYVVFPQD--DPSEIQPLTEKSEL------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VKC2-1", "uniprot_id": "Q9VKC2_DROME", "id": "Q9VKC2-1", "name": "", "aln": "------------------------MTDRYANGVTTSLVEPTNGCAAPGNPNPADGEEKIVLKRKLTLINGVAIIVGTIIGSGIFIAPTGVFIYTE-SVGSSLLIWLTCGILSTIGALCYAELGTCITRSGGDYAYLLVSFGPLVGFLRLWIALLIIRPTTQTIVALSFAHYAVKPFFPECDPPQNAVKLLAAICLTLLTTINCLSVKVSMKVQDVFTVGKLLALIMIILSGLYYMATGELENFRN--------PWEGIYTARNIGYAFYSGLFAFGGWNYLNFVTEELQDPYKNLPRAIWIAMPLVTSIYVLVNLAYFAVVNKPEMLSS-LAVAVTFGNRVFG--PLAFMVPIFVALSTFGGVNGVLFTSARLFATGAQEGHLPKFFQLFHVKQQTP----IPSLIFTCLMSLLMLLT-DNVYQLIN-YFSSVLWLSVVASIAGMLWLRHKRP----DLPRPIKVHLALPITFMVSCVTLVLLPNLEEP------------QNLLIGIGITLAGIPFYYAFIARKKKP---KCYGRLSNSVV----EICRAIFNTTIIESNEAIN-------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P50276-1", "uniprot_id": "MUP1_YEAST", "id": "P50276-1", "name": "High-affinity methionine permease", "aln": "----MSEGRTFLSQLNVFNKENYQFSSSTTKKEVSNSTVDADNGASDFEAGQQFATELDQGEKQLGILSCIGLICNRMLGTGVFAVSSTIYTLCG-SVGLALIMWAVGAIIAISGLYVYMEFGTAIPKNGGEKNYLEAIFRKPKFFITCMYAAYIFFLGWAAGNSINTAIMFLTAADTEVTKWN--QRGIGVAVVFFAFLINSLNVKIGLYLQNILGIFKIGIVLFISITGWVALGGGLKDGYQSHNF-RNAFEGTETATAYGIVNALYSVIWSFVGYSNVNYALGEVKNPVRTLKIAGPTSMVFLAIIYIFVNIAYFAVVPKDKLISSKLILAADFFDIVFGG-QAKRAAAALVGLSALGNVLSVIFSQGRIIQQLGREGVLPFSNFFASSKPFNSPMVGLFQHFIVCTVTILAPPP-GDAYLLVQNLISYPMNIINFAISAGLLWIYWQRRQGKIEWNPPIKAGVFVTGFFTLSNLYLIIAPYVPPSNGESVYSSMPYWIHCVIAWGIFFFGGVYYVVWAQLLPRWGHYKLVSKDVLGEDGFWRVKIAKVYDDTIGDVDTQEDGVIETNIIEHYKSEQEKSL", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P38734-1", "uniprot_id": "MUP3_YEAST", "id": "P38734-1", "name": "Low-affinity methionine permease", "aln": "MEPLLFNSGKANPSQDVFIDVEVGDITTKYGSTNTGSFSSMDTVEAQAIKAETARFMEVPQGRHLGVFSTVVLFVSRIMGSGIFAVPSVILLNTGGNKLIYFAIWVFSAAIAFAGLYLFLEFGSWIPKSGGRKNFLERSFERPRLLISVVFSCYSVLTGYALTGSIVFGKYVLSAFG---VTDDSWSKYVSISFIIFAVLIHGVSVRHGVFIQNALGGLKLIMIVLMCFAGLYTLFFYKSTGQVAWDLPVTQVEKDSLLSVSSIATAFISSFFCFSGWDTVHTVTSEIKNPVKTLKVSGPLSLIICFVCYTMMNVAYLKVLTYEEIVSAGPLVGSVLFTKLFGPRVGGKFIAFSIAISAASNILVVIYSISRVNQEIFKEGYLPFSIHMSKNWPFDAPLPSISLCGFITIAWILILPKEGESFNYLVSMDGYGNQFFLLLVAIGLFIWRFKHK----NEVPEIRASTFGVLAIITLSLYMLMAPFFADPSLNRVG---FLPPYQIMSLLVIVACFFFWLVKFVLLPKF----FHYKLLPKITYLHDGLIVTEWVKKPCLC------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :.: :.. :: . ::*:*:* .. : . : :* . : * : *:* *.:.** :: * :: : . :: . : . : :. : : :: .*: . :* : *: : :: * : : : *: :.: *:. :: . *: :. :.* : :: : * : *:**: : :::.: :. : ::* . :.:*: ..: ::: .*: :** ** : . : . : .: . : . : *:: :: *:. :: . . :. : . : : : ", "identical_positions": 32, "similar_positions": 130, "identity": "5.48%" }, { "cls_id": "homologset.agr.MGI:1858271", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9Z2C4-1", "uniprot_id": "MTMR1_MOUSE", "id": "Q9Z2C4-1", "name": "Phosphatidylinositol-3-phosphate phosphatase MTMR1", "aln": "MDRPVAAAAAASAASCEGAGGPGPGPGASWRPSRVAGGASASSRHPSIETLDSPTGSHVEWCKQLIAATISSQISGSVTSENVSR----------------DYK-------------------------ALRDGNKLAQMEEAPLFPGESIKAIVKDVIYICPFMGAVSGTLTVTDFKMYFKNVER----------DPHFVLDVPLGVISRVEKIG-AQSHGDNSCGIEIVCKDMRNLRLAYKQEEQRKLGIFENLNKHAFPLSNGQVLFAFNYKEKFPV------NGWKVYDPVSEYKRQGLPNE----SWKISKINSNYEFCDTYPAIIVVPTSVKDDDLSKVAAFRAKGRVPVLSWIHPESQATITRCSQPLVGPNDKRCKEDE----KYLQTIMDANAQSHKLTIFDARQNSVADTNKAKGGGYENESAY-----------------PNAELIFLEIHNIHVMRESLRKLKEIVYPSIDE-----SHWLSNVDGTHWLEYIRVLLAGAVRIADKIESGKTSVVIHCSDGWDRTSQLTSLAMLMLDSYYRTIKGFEALIEKEWISFGHRFALRVGHG-------------------------------DDNHADADR--------------------------------SPIFLQFIDCVWQMTRQFPSAFEFNELFLITILDHLYSCLFGTFLCNCEQQRIKEDVYTNTISLWSYINSQLDEFSNPFFVNYEN---HVLYPVASMSHLELWVNYYVRWNPRMRPQMPIHQNLKELLAIKAELQKRVEDLQREMAT-RTISSSSERGSSPTHSATPVHTSV", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8I5Y1D5-1", "uniprot_id": "A0A8I5Y1D5_RAT", "id": "A0A8I5Y1D5-1", "name": "phosphatidylinositol-3,5-bisphosphate 3-phosphatase", "aln": "MDRPGAAASG-----CESAAGPGPGPGASWRPARVAGGASGSSRHPSMETLDSPAGSHVEWCKQLIAATISTQMSGSVTSENVSR----------------DYKVFRRPDTRELQEEHNGYPSAAEADQALRDGNKLAQMEEAPLFPGESIKAIVKDVIYICPFAGAVSGTLTVTDFKMFFKNVER----------DPHFILDVPLGVISRVEKIG-AQSHGDNSCGIEIVCKDMRNLRLAYKQEEQRKLGIFENLNKHAFPLSNGQALFAFNYKEKFPV------NGWKVYDPVSEYKRQGLPNE----SWKISKINSNYEFCDTYPAVIVVPTSVKDDDLLKVSAFRAKGRVPVLSWIHPESQATITRCGQPLVGPNDKRCKEDE----KYLQTIMDANAQSHKLTIFDARQNSVADTNKAKGGGYECESAY-----------------PNAELIFLEIPNIHVMRESLRKLKEVVYPAIDE-----SHWLSNVDGTHWLEYIRVLLAGAVRIADKIESGKTSVVVHCSDGWDRTPQLTSLAMLMLDSYYRTIPGFEALIEKEWISFGHRFALRVGHG-------------------------------DDNHADADR--------------------------------SPIFLQFIDCVWQMTRQFPSAFEFNELFLIAILDHLYSCLFGTFLCNCEQQRVREDVCAKTLSLWSYINSQLDEFSNPFFVSYDH---HVLYPVASVSRLELWVNYYVRWNPRMRPQMPIHQNLKELLAVKAELRKRVEDLQREAAA-RTVPSSSERGPSPTHSAPPVHTSV", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q13613-1", "uniprot_id": "MTMR1_HUMAN", "id": "Q13613-1", "name": "Phosphatidylinositol-3-phosphate phosphatase MTMR1", "aln": "MDRPAAAAAAG----CEGGGGPNPGPAGGRRPPRAAGGATAGSRQPSVETLDSPTGSHVEWCKQLIAATISSQISGSVTSENVSR----------------DYK-------------------------ALRDGNKLAQMEEAPLFPGESIKAIVKDVMYICPFMGAVSGTLTVTDFKLYFKNVER----------DPHFILDVPLGVISRVEKIG-AQSHGDNSCGIEIVCKDMRNLRLAYKQEEQSKLGIFENLNKHAFPLSNGQALFAFSYKEKFPI------NGWKVYDPVSEYKRQGLPNE----SWKISKINSNYEFCDTYPAIIVVPTSVKDDDLSKVAAFRAKGRVPVLSWIHPESQATITRCSQPLVGPNDKRCKEDE----KYLQTIMDANAQSHKLIIFDARQNSVADTNKTKGGGYESESAY-----------------PNAELVFLEIHNIHVMRESLRKLKEIVYPSIDE-----ARWLSNVDGTHWLEYIRMLLAGAVRIADKIESGKTSVVVHCSDGWDRTAQLTSLAMLMLDSYYRTIKGFETLVEKEWISFGHRFALRVGHG-------------------------------NDNHADADR--------------------------------SPIFLQFVDCVWQMTRQFPSAFEFNELFLITILDHLYSCLFGTFLCNCEQQRFKEDVYTKTISLWSYINSQLDEFSNPFFVNYEN---HVLYPVASLSHLELWVNYYVRWNPRMRPQMPIHQNLKELLAVRAELQKRVEGLQREVAT-RAVSSSSERGSSPSHSATSVHTSV", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AC58FYQ3-1", "uniprot_id": "A0AC58FYQ3_DANRE", "id": "A0AC58FYQ3-1", "name": "phosphatidylinositol-3,5-bisphosphate 3-phosphatase", "aln": "MEKQQQHHPSG---------SESPVLPPVARKPRNLG-VNPASRQDSVDSLDSPTGSHVEWCKQLIAATISSQITSGVPSESIHRESKIGKKIDTRVSKRPNFRSQDSGEDGCQFDSDCELP--SHTSQVFRDVRRPAPMDEVPLVPGETIKTTVKDVMYICPFTGAVTGTLTITDYKLYFVSLER----------DAPFILDVNLGAISRLETIS-VQSLGENTSGMEIVCKDMRSPRFAYKKEEQSKLEILETLTKYAFPLSNELSLFAFQYKEQFPE------DGWKVYDPVAEYKRMGLPNE----SWSISKINSNYEVCDTYPALLVTPTSIKEDEIRRVASFRVKHRIPVLSWIHPETQATIVRCSQPMVGPTDRRCKEDE----HYLQTIMDANAQSHKLAIFDARQNTVAHNHKTKDGGYENENFY-----------------PNMELNFLEIPNIHVMRESLRKLKEVVYPTIEE-----QRWHSAIDATHWLEYIRLLLAGAVRIADKVESSKSSVVVHCSDGWDRTAQLTSLSMLMLDSYYRTLRGFQVLLEKEWISFGHKFAARIGHG-------------------------------DENHANSER--------------------------------SPLFVQFIDCVWQMMRQFPSAFEFNELFLITILDYLYSCLFGTFLYNSEQERVEKEVNRKTVSLWSYINSQSEDFTNPFYVDYEN---HVLYPLASLRHLELWVGYYVRWNPRMRPQMPVHQNLKELLYLRAELQRKVEELQKDVSSSRSVSSSSEHAYSPSHGGTPLHSSV", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0AC58I8Q3-1", "uniprot_id": "A0AC58I8Q3_DANRE", "id": "A0AC58I8Q3-1", "name": "phosphatidylinositol-3,5-bisphosphate 3-phosphatase", "aln": "MDKR------------------------------------PTSPQSNAETPDSPTGAHVEWCKQLIAATMSSQSCGPISSEMISR----------------EYKDCDMEVKGFLLDSDPQQ---TAPSSALREGNKQAQMEEAPRIPGETIKAIVKDVMYICPFSGVIRGTLTITDFKLYFKSLTRVNSLLKLSSGDSPFVLDVNLGAVSRLESIA-VQSHGDDTQGLEIVCKDLRTPRFAYKKEGQSNLEMFKILSKYAFPLSHNLPLFAFKYRETFPE------DGWKIYDPVAEYKRQGLPNE----SWIISKVNSGYEVCETYPALLVLPSNVTEDELKRVAAFRAKRRFPVLSWIHPESQAAIVRCGQPQVGPSDRRCREDE----RYLQTILDANAQSHKLCIFDARQSTVADTNKAKDGGYENESFY-----------------INVELNFLEIPNIHVMRESLRKLKEVVYPAIDQ-----QHWFSNVDATHWLEYVRLLLAGAVRIADRIESGKTSVVVHCSDGWDRTAQLTSLAMLMLDAHYRSLKGFQVLLEKEWLSFGHRFASRVGHG-------------------------------DGNHANSER--------------------------------SPLFVQFIDCVWQMTRQFPSAFEFNELFLITVLDHLFSCLFGTFLYNSEQERVSKEVYNKTVSLWSYVNSQIEEFTNPLYVNYEH---HVLYPIASLRHLELWVSYYVRWNPRMRPQVPIHQSLKELLVLKSELQKRVEDLKQDAASSNSLSSS-------EHEGMPMQTTV", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VMI9-1", "uniprot_id": "Q9VMI9_DROME", "id": "Q9VMI9-1", "name": "phosphatidylinositol-3,5-bisphosphate 3-phosphatase", "aln": "----------------------------------------MDPSASLADKLASKTASSNSLDSSSKSSSLGSKHGGGENG-------------------------------------------------ILRDTP-------FGYLEGEEDQDQKNDVTYVCPYRGPVFGALTITNYRLYFRSLPLRDQ-------EPPVVVDVPLGVIARVEKIGGATSRGENSYGIEIFCKDMRNLRFAHKQQNHSRRTVFEKLQANAFPLSYSGRLFAFAHAAANSVNGNGGWDGWAVYEPLAELRRLGVPND----MWRATKLNESYAICDSYPAVWAVPKAASDDFLRRVAQFRSRCRLPVLSWMNPRTQATITRCSQPLVGVSGKRNSDDE----AYLSFIMEANAQSDKLTIMDARPSANAIANKAKGGGYESEDAY-----------------KNVEINFLDIHNIHVMRESLRKVKEACFPTTDD-----SKWQTAIDNTLWLKHIRCILAGAVRIVDKVETMSTSVVVHCSDGWDRTAQLTALSMLLLDPHYRTVRGFEVLIEKEWLSFGHKFQQRIGHG-------------------------------DNKHSDADR--------------------------------SPVFLQFIDSVWQVSQQFNNAFEFNEHFLITIVDHLYSCRFGTFLCNTEAERVAEDLKHKTTSLWTHINSSLDQYLNPLFPSFTHGAELVLRPIASVRSVRLWKGLYCRWNPGLCAPQHGCQRTRELLSKQDQLFKLVNELRLKSNN-RSNSMQT-----TTRLASPMH---", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P47147-1", "uniprot_id": "YMR1_YEAST", "id": "P47147-1", "name": "Phosphoinositide 3-phosphatase", "aln": "--------------------------------------MEYIKIAKVSNVVLHRRGTATQGTLHLTTHHLIFESPQLSTEFWFP----------------------------------------------------------YPLIYGVHKNPGSTLLSKLTSTNQIQLEGTDSQNYKLYQG---------------------KDLWSFVNIKVIG----------------KDYAVFSLDFGGDLHLQARKVYDSILNLTVLSNITQLYAFIYISNNLERKLPSPDSWDIYDPIKEFRRQGLDSKDETCPWRLSTVNEHYEFCPTYPSKLFVPRSTSDILLKHASKFRSQKRIPVLTYHHKATDCNILRSSQPLPGLINQRSIQDEKLVWESFNSFCNKDIRRTKHVIVDARPRTNALAQMALGGGTENMDNYNFFLADNNMGVDKSLKLPTVTRLFLGIDNIHIVSNTAAYMTEVICQGGDLNLPLEQNLIRSQKFSNWLKLNTLILKSVDMLLKSIIFNHSNVLVHCSDGWDRTSQVVSLLEICLDPFYRTFEGFMILVEKDWCSFGHRFLERSGHLNSDIRFHDNTMHSNFNDVDTNGDDLDIGVNTQDDYAEDDEGGEDETNLINLSRISKKFNENFKLNKKSLKFVSPVFQQFLDCVYQLLTQNPDLFEFNERFLRRLVYHLYSCQYGTFLSNSEKEKFQQNLPNKTKSVWDYFRSRRKQFINPNFIQRKR---SGMNEHDQNLEEEEKVEWISPDLKKVQWWWQLYGRKDSEMNDELRHKRDSVPISVDKKSKEHSNSDGGKGLNLSIFGFDMFNRK", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : .: . : : : . * : . : : . ::::: * . .:: *. ** : . : : . . ** *:** : :.* :*:*: * :* *: .. * :.:*. * .* :**: * .: : :.: ** : *.***:: : ::. * *..** * .:* :** :. : : : : * *.*** : * : : .** * . * . ** * ***:: :: :.* : . . : **: :* .. : . : :.*::*********.*:.:* : **..**:. ** *:**:* ****:* * ** : .::: :. **:* **:*.*:*: * . ***** ** :: :*:** :**** * * ::. ::: :* *:* :..* .:: ** : . . : . . : . : . . : : . . . . : ", "identical_positions": 118, "similar_positions": 162, "identity": "14.32%" }, { "cls_id": "homologset.agr.MGI:1858277", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZCT9-1", "uniprot_id": "D3ZCT9_RAT", "id": "D3ZCT9-1", "name": "", "aln": "MRDDREGMAEWSRSSPKGYQIGDLWNHQWFPEMTLLPKKPCKSKAKGLVLGALLTSFLLLLYSYVVPPLYPNLAFTTSEAAAPCSPVPNEPVAATPANGSAG-GCQPRRDIVFMKTHKTASSTLLNILFRFGQKHELKFAFPNGRNDFHYPSYFARSLVQDYRPGACFNIICNHMRFHYEEVRGLVRPGATFITVIRDPARLFESSFHYFGSVVPLTWKLSSRDKLAEFLQDPDRYYDPSSYNAHYLRNLLFFDLGYDSSLDPGSPRVQEHILEVERRFHLVLLQEYFDESLVLLRELLCWDLEDVLYFKLNARRDSPEPRLSGELYRRATAWNLLDVRLYRHFNASFWRKVEAFGRERMASEVAKLRRANEHMRSICIDGGQAVDAEAIQDSAMQPWQPLGIKSILGYNLKKSIGPQHEQLCRRMLTPEIQYLSDLGANLWITKLWKFFRDFLRW----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9JHE4-1", "uniprot_id": "G3ST1_MOUSE", "id": "Q9JHE4-1", "name": "Galactosylceramide sulfotransferase", "aln": "--------------------------------MTLLPKKPCKSKAKGLLLGALFTSFLLLLYSYVVPPLYPNMAFTTSEAAAPCSPIPNEPVAATPANGSAG-GCQPRRDIVFMKTHKTASSTLLNILFRFGQKHELKFAFPNGRNDFHYPSYFARSLVQDYRPGACFNIICNHMRFHYEEVRGLVRPGATFITVIRDPARLFESSFHYFGSVVPLTWKLSSRDKLAEFLQDPDRYYDPSSYNAHYLRNLLFFDLGYDSSLDPASPRVQEHILEVERRFHLVLLQEYFDESLVLLRELLCWDLEDVLYFKLNARRDSPVPRLSGELYRRATAWNLLDVRLYRHFNASFWRKVEAFGRERMAREVAELRQANEHMRHICIDGGQAVGAEAIQDSAMQPWQPLGIKSILGYNLKKSIGPQHEQLCRRMLTPEIQYLSDLGANLWVTKLWKFLRDFLRW----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q99999-1", "uniprot_id": "G3ST1_HUMAN", "id": "Q99999-1", "name": "Galactosylceramide sulfotransferase", "aln": "--------------------------------MLPPQKKPWESMAKGLVLGALFTSFLLLVYSYAVPPLHAGLASTTPEAAASCSPPALEPEAVIRANGSAG-ECQPRRNIVFLKTHKTASSTLLNILFRFGQKHRLKFAFPNGRNDFDYPTFFARSLVQDYRPGACFNIICNHMRFHYDEVRGLVPTNAIFITVLRDPARLFESSFHYFGPVVPLTWKLSAGDKLTEFLQDPDRYYDPNGFNAHYLRNLLFFDLGYDNSLDPSSPQVQEHILEVERRFHLVLLQEYFDESLVLLKDLLCWELEDVLYFKLNARRDSPVPRLSGELYGRATAWNMLDSHLYRHFNASFWRKVEAFGRERMAREVAALRHANERMRTICIDGGHAVDAAAIQDEAMQPWQPLGTKSILGYNLKKSIGQRHAQLCRRMLTPEIQYLMDLGANLWVTKLWKFIRDFLRW----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M3ARZ7-1", "uniprot_id": "A0A8M3ARZ7_DANRE", "id": "A0A8M3ARZ7-1", "name": "", "aln": "-------------------------------MMVGKPVRQWRSICKGLILGALLTTCMILLYCLSAPEVQFGLQEVPVPYSCAHRPSAAHSIPNSSHHPSGQPICTPKVDIVFMKTHKTASSTFLNILFRFGEKHHLKFAFPNSRNDFFYPSSFHRSQVKDYRPGMCFNIICNHMRFNAAEVARVLPADASYITILRDPADLAESSFHYFGRVVPLTWKISGEDKLREFLSDPNLYYDPEGFNSFYLKNLLFFDFGQDNNLNPDDPRVDQAIQEISKRFQLVMLVEYFEESLILLKDALCWEMEDLLFFKLNARKDSTISKLTPELRSKALQWNAIDWKLYQYFNDTFWRKVDAYGRQRMIRDVAELRRRNAEMAAVCIEGGQAVDAGSILETSMQPWQPIGERSIMGYNLKKNIDKAHRRLCRKMLTPELQYLSDMGVNLWITRLWGHIRDILHW----", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "E9QCM2-1", "uniprot_id": "E9QCM2_DANRE", "id": "E9QCM2-1", "name": "", "aln": "--------------------------------MGTRAKR----RTQKLFLGAFVI-CIMGFYSYTAP----TLLATHSVSLAPCAPTSDTWNGSRRTLQEHR-SCTPKVNLMFMKTHKTASSTLMNILLRFGEKHQLKFALPDGRNDFFYPSSFFRTQVKSYQPGVCYNIVCNHMRFNAPEVEKLLPADAFFFTILRDPAELFESSFHYYKGYVPQTWRIPGDNQFKEFLSNPNQYFNPTGINAFYLKNLQFFDFGFENNLNSDDPRVRQGIEYIEKRFQLVLISDHFEESLILLKDALCWQMDDLMFFKLNARSVSSVSPMSPELRTQARQWNGADWQLYQHFNNTFWARVEAYGKSRMEEHVKELRRRNAEMEAICIDGGRAVEAKDITDTHMKPWQPLGKASILGYNLRTDIDQHYQELCRKMLTPEIQYLTNLGVSLWVTRLWGWFKDSVVQFGLS", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * : : *.***:. :: .*. .* : . .. * . . * *: :::*:*********::***:***:**.****:*:.**** **: * *: *:.*:** *:**:******: ** :: ..* ::*::**** * ******: ** **::.. ::: ***.:*: *::* . *:.**:** ***:* :..*:. .*:* : * :.:**:**:: ::*:***:**:: ***:::*:::****** *. . :: ** :* ** * :**::** :** :*:*:*:.** .* **: * .* :**:**:** * * : *:****:* **:****:..*. : .***:*****:*** ::*..**:*:** ::* : ", "identical_positions": 174, "similar_positions": 130, "identity": "37.83%" }, { "cls_id": "homologset.agr.MGI:1858303", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "F7FND9-1", "uniprot_id": "F7FND9_RAT", "id": "F7FND9-1", "name": "Serine/arginine repetitive matrix protein 1", "aln": "MDAGFFRGTSAEQDNRFSNKQKKLLKQLKFAECLEKKVDMSKVNLEVIKPWITKRVTEILGFEDDVVIEFIFNQLEV-KNPDSKMMQINLTGFLNGKNAREFMGELWPLLLSAQENIAGIPSAFLELKKEEIKQRQIEQEKLASLKKQDEDKDKRDKEEKESSREKRERSRSPRRRKSRSPSPRRRSSPVRRERKRSHSRSPRHRTKSRSPSPAPEKKEKSPELPEPSVRMK-DSSVQEATSTSDILKAPKPEPVPEP-KEPSPEKNSKKEKEK--TRPRS-RSRSKSRSRTRSRSPSH-TRPRRRHRSRSRSYSPRRRPSPRRRPSPRRRTPPRRMPPPPRHRRSRSPGRRRRRSSASLSGSSSSSSSSRSRSPPKKPPKR-TSSPPRKTRRLSPSASPPRRRHR-PSSPATPPPKTRHSPTPQQSNRARKSRVSVSPGRTSGKVTKHKGTEKRESPSPAPKPRKVELSESEEDKGSKMAAADSVQQRRQYRRQNQQSSSDSGSSSTSEDERPKR----SHVKNGEVGRRRRHSPS----RSASPSPRKRQKETSPRMQMGKRWQSPVTKSSRRRRSPSPPPARRRRSPSP---------APPPPPPPPP-RRRRSPTPPPRRRTPSPPPRRR---SPSPRR---YSPPIQ-----RRYSPSPPPKRRT--------ASPPPPPKRRASPSPPPKRRVSHSPPPKQR---SPPVTKRRSPSLSSKHRKGSSPGRSTREARSPQ------PNKRHSP----SPRPRAPQTSS-PPPVRRG-------------ASASPQGRQ--------------SPSPSTRPIRRVSRTPEPKKIKK-----------------------AASPSPQSVRRVSSSRSVSGSPEPTAKKPPAPPSPVQSQSPSTNWSPAAPAKKAKSPTPSPSPARNSDQEGGGKKKKKKKDKKHKKDKKHKKHKKHKKEKAVAVATPAPAAPAAVSAAATPSAQEEPAAAPEPRKETESEAEDDNLDDLERHLREKALRSMRKAQVSPQS--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q52KI8-1", "uniprot_id": "SRRM1_MOUSE", "id": "Q52KI8-1", "name": "Serine/arginine repetitive matrix protein 1", "aln": "MDAGFFRGTSAEQDNRFSNKQKKLLKQLKFAECLEKKVDMSKVNLEVIKPWITKRVTEILGFEDDVVIEFIFNQLEV-KNPDSKMMQINLTGFLNGKNAREFMGELWPLLLSAQENIAGIPSAFLELKKEEIKQRQIEQEKLASLKKQDEDKDKRDKEEKESSREKRERSRSPRRRKSRSPSPRRRSSPVRRERKRSHSRSPRHRTKSRSPSPAPEKKEKSPELPEPSVRMK-DSSVQEATSTSDILKAPKPEPVPEP-KEPSPEKNSKKEKEK--TRPRS-RSRSKSRSRTRSRSPSH-TRPRRRHRSRSRSYSPRRRPSPRRRPSPRRRTPPRRMPPPPRHRRSRSPGRRRRRSSASLSGSSSSSSSSRSRSPPKKPPKR-TSSPPRKTRRLSPSASPPRRRHR-PSSPATPPPKTRHSPTPQQSNRTRKSRVSVSPGRTSGKVTKHKGTEKRESPSPAPKPRKVELSESEEDKGSKMAAADSVQQRRQYRRQNQQSSSDSGSSSTSEDERPKR----SHVKNGEVGRRRRHSPS----RSASPSPRKRQKETSPRMQMGKRWQSPVTKSSRRRRSPSPPPARRRRSPSP---------APPPPPPPPPPRRRRSPTPPPRRRTPSPPPRRR---SPSPRR---YSPPIQ-----RRYSPSPPPKRRT--------ASPPPPPKRRASPSPPPKRRVSHSPPPKQR---SPTVTKRRSPSLSSKHRKGSSPGRSTREARSPQ------PNKRHSP----SPRPRAPQTSS-PPPVRRG-------------ASASPQGRQ--------------SPSPSTRPIRRVSRTPEPKKIKKTAMATQRNIRRVSKSPKADSLSRAASPSPQSVRRVSSSRSVSGSPEPAAKKPPAPPSPVQSQSPSTNWSPAVPAKKAKSPTPSLSPARNSDQEGGGKKKKKKKDKKHKKDKKHKKHKKHKKEKAVTIATPATAAPAAVSAATTTSAQEEPAAAPEPRKETESEAEDDNLDDLERHLREKALRSMRKAQVSPQS--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8IYB3-1", "uniprot_id": "SRRM1_HUMAN", "id": "Q8IYB3-1", "name": "Serine/arginine repetitive matrix protein 1", "aln": "MDAGFFRGTSAEQDNRFSNKQKKLLKQLKFAECLEKKVDMSKVNLEVIKPWITKRVTEILGFEDDVVIEFIFNQLEV-KNPDSKMMQINLTGFLNGKNAREFMGELWPLLLSAQENIAGIPSAFLELKKEEIKQRQIEQEKLASMKKQDEDKDKRDKEEKESSREKRERSRSPRRRKSRSPSPRRRSSPVRRERKRSHSRSPRHRTKSRSPSPAPEKKEKTPELPEPSVKVK-EPSVQEATSTSDILKVPKPEPIPEP-KEPSPEKNSKKEKEKEKTRPRS-RSRSKSRSRTRSRSPSH-TRPRRRHRSRSRSYSPRRRPSPRRRPSPRRRTPPRRMPPPPRHRRSRSPVRRRRRSSASLSGSSSSSSSSRSRSPPKKPPKR-TSSPPRKTRRLSPSASPPRRRHR-PSPPATPPPKTRHSPTPQQSNRTRKSRVSVSPGRTSGKVTKHKGTEKRESPSPAPKPRKVELSESEEDKGGKMAAADSVQQRRQYRRQNQQSSSDSGSSSSSEDERPKR----SHVKNGEVGRRRRHSPS----RSASPSPRKRQKETSPR--------------GRRRRSPSPPPTRRRRSPSP---------APPP-------RRRRTPTPPPRRRTPSPPPRRR---SPSPRR---YSPPIQ-----RRYSPSPPPKRRT--------ASPPPPPKRRASPSPPPKRRVSHSPPPKQR---SSPVTKRRSPSLSSKHRKGSSPSRSTREARSPQ------PNKRHSP----SPRPRAPQTSSSPPPVRRG-------------ASSSPQRRQ--------------SPSPSTRPIRRVSRTPEPKKIKK-----------------------AASPSPQSVRRVSSSRSVSGSPEPAAKKPPAPPSPVQSQSPSTNWSPAVPVKKAKSPTPSPSPPRNSDQEGGGKKKKKKKDKKHKKDKKHKKHKKHKKEKAVAAAAAAAVTPAAIAAATTTLAQEEPVAAPEPKKETESEAED-NLDDLEKHLREKALRSMRKAQVSPQS--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "E7F1X7-1", "uniprot_id": "E7F1X7_DANRE", "id": "E7F1X7-1", "name": "Serine/arginine repetitive matrix protein 1", "aln": "MDAGFFRGTSAEQDNRFSNKHKKLLKQLKFAECLEKKVDMTKVNLEVIKPWITQRVTEILGFEDDVVIEFVFNQLEE-KNPDGKMMQINLTGFLNGKNAREFMKDLWPLLLSAQENIAGIPSAFLEQKKEEIKQRQIEQEKLASLKKVDED--KREKENKE-----RAQSKSPKRRKSRSPVKRDRKSSPSRSRSPRRKISP----AASPPSSPPNHKEEPKREPDQSESSKPEPLIQEASSTSDLVTEMKPDSVSEPVKESSPDKTSKSEDRP-KPRDRE-KDGRKDRPRHRSRSRS--PRSRRRPRSRSRSFSPRRRTSPRRRISPRRRSPPRRQPPS-RHRRSRSPVRRRR------SRSRSSSGSSSSRSPHKRAGKRGSATPPRKLARRTDLSSPPRRRGRSPSGPDTSPSAGKHRPG----------------GRN-------------DSRSPSPKPRRSDASDSEEDKLGKGSTADSVQQRRQYRRQNQQSSSDTGSSSSSEDEGPRRQNRGAGARNGEIRRRRSHSPASPRRRHRDASPRKRRSPSPPGRRHRSQ------SPVRRRRSPSPPPRRRSPSPPPRRFTPPIQRRYSPPSPSPAQKRRSSGSPPKRRRSPSPMPKRRIPPSPPPKRRMSPSPPPK-----RRKSPSPMSKRRTSPSVSKRRTSPSPVAKHRRSPSPMSKRRTCASPVSKRRNSPSPAPQRRSSPSPMPKHRGSPSPVTKRHTSRSPKRSRGTSPGKRRTPPSSASPPPRHRRNSPNPPAAQRGRDTRSSPPAHTTRVSSSPPGRYGASGSSPQRQRRQTSPSHSTRPIRRVSRTPEPRKSQR------------------------GSQSPPPERRQ-VSRSPSASPPPAQKRPAS-----VSPSRSTSRSPPPPAKKNSSVSPSPSPNKNSDAEGG-KKKKKKKEKKHKKDKKHKKHKKQKKEKGGEEK----------SGGATGGHGPEAEPDSDQKKESESEVED-SLDDLEKHLREKALRSMRKAQMSPSSQS", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VU43-1", "uniprot_id": "Q9VU43_DROME", "id": "Q9VU43-1", "name": "Serine/arginine repetitive matrix protein 1", "aln": "---MMFTGTNQQQDTRFSDKEKKLMKQMKFGDCLNKRVDMSKVKLDVLRPWISKKITDILHIEDDVVVEFVYNQLEEEKYPCPKKMQINMTGFLNGRNARQFMGELWALLLSAQESDSGIPAEFIQQKKDEILKREEEQRQRDRSRSRSRSRSQRDSSRRDRQRD-RSKSKSRSRSRSMKPANNNGSVPSAAREAAANAAAKIRKRGSSSAARPGSRERRSSRRPRSRSRSRSRTAGKKTGSVEPAPAKTVNGRHSTDKSSPVPPASKNKSRSRSHSRSRSPRSRSRSPSAKRSRSRSSSRRSRRRGRSSSISLSPERNQDQFEHRRNKNSVQNKRQYRNNRGDSASS-MERGNDRGRQFGGGGGGRRGGRRFSPRGRSPMRQDNGGGNGGNRFQRSNSRRRSRSR---RLSRSPMRYSRSPRRFNNRRRSPMMNFRGGGRGGGRGGGHRQMWQHRGGSPNFRGGGRIHWQARHSPGGGGRGGGGGMGRFDRRQSPQQNRYNRDHRQSPMQQNQPFR----KQFSPHQGPGRRFSSPQQRRNSRDRRPNSRERRSSPGGGGGHMNRWDNPPPARNRRSSSGSSAGGRQQRQR---------SASPPEKRRSSHSRSRSLSRNRSRSRSSSQHSRKRESPIGRSSVEYAGPAVNTIDLCREEQQRKNKPETIIVLDEGPAVRSSYASLSRTPSPFLKPHERLAAAKAAAAASAAVPKKSRDQSQSSSSDSSAESDDSEEQPRRKKQ-----PTNMETSKGKKEKVRRSSESSTSSEQSDDE-------------DNSSGDERLKKKLQQ--------RKSKEAAALKGKEKEHEKEKDKR--------------------------RSDKKSKRGAISSGDEESTSSRKRGHKKTRRDEAGDNSDSEDEHVPKKKRKKAKKPADSSDSDSEASSKRKKHKKHKKHSKKSKKHKKHKRKCSAGKSRADSSSQGSSDEDEQLPHSVAAKRNGNAGKLALLLPGASGAGVINEDLEKQLRERALKSMKKLD-------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :* **. :**.***:*.***:**:**.:**:*:***:**:*:*::***::::*:** :*****:**::**** * * * ****:******:***:** :**.*******. :***: *:: **:** :*: **.: :. ... :*:...:: * :*:* * :* .* . . . . . : : ..: . .::... . * : . ::: *.. . ... * ..:.. .* *. :. :. . **** * *.*** ** * * **.*. . .: :. :* * : * .* . . . .. .. ** :. * . * * * * * .* : * ** . ** : ::... . ... * : *:. **. : . .:. :: . . * .*.. . . *..*. :.* *.***.* .. . .* : * . * *: *. : * ** : : * * . . * .* : .. .. :*** * : :. :. : . * .. .... . . .* : * : .:. . * ..*. . .:* * * .: .:: .: * .* :: * :* * . . *. . : . . .:. . *: .: .*: *. :*: .. **:**:*.:.:*..*::*:::* . *. : : . . :. . :***::***:**:**:* : ", "identical_positions": 196, "similar_positions": 266, "identity": "18.96%" }, { "cls_id": "homologset.agr.MGI:1858304", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "F7F0L0-1", "uniprot_id": "F7F0L0_RAT", "id": "F7F0L0-1", "name": "CTP synthase", "aln": "-------------------------MKYILVTGGVISGIGKGVIASSVGTILKSCGLHVTSIKIDPYINIDAGTFSPYEHGEVFVLDDGGEVDLDLGNYERFLDIRLTKDNNLTTGKIYQYVINKERKGDYLGKTVQVVPHITDAIQEWVMRQALIPVDEDGLEPQVCVIELGGTVGDIESMPFIEAFRQFQFKVKKENFCNIHVSLVPQPSSTGEQKTKPTQNSVRELRGLGLSPDLVVCRCSNPLDTSVKEKISMFCHVEPEQVICVHDVSSIYRVPLLLEEQGVVDYFLRRLDL-----PVERQSR--KMLMKWKEMADRYDRLLETCSIALVGKYTKFSDSYASVIKALEHSALAINHKLEIKYIDSTDLEPSTLQEEPVRYHEAWQKLCSAHGVLVPGGFGVRGTEGKIQAIAWARKQKKPFLGVCLGMQLAVVEFSRNVLGWQDANSTEFDPKT----SHPVVIDMPEHNPGQMGGTMRLGKRRTLFQTKN--SVMRKLYGDTDYLEERHRHRFEVNPVLKKCLEEQGLKFVGQDVEGERMEIVELEDHPFFVGVQYHPEFLSRPIKPSPPYFGLLLASVGRLPHYLQKGCRLSPR---DTYSDRS----GSSSPDSEITELKFPSISQD-----------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P70698-1", "uniprot_id": "PYRG1_MOUSE", "id": "P70698-1", "name": "CTP synthase 1", "aln": "-------------------------MKYILVTGGVISGIGKGVIASSVGTILKSCGLHVTSIKIDPYINIDAGTFSPYEHGEVFVLDDGGEVDLDLGNYERFLDIRLTKDNNLTTGKIYQYVINKERKGDYLGKTVQVVPHITDAIQEWVMRQALIPVDEDGLEPQVCVIELGGTVGDIESMPFIEAFRQFQFKVKRENFCNIHVSLVPQPSSTGEQKTKPTQNSVRELRGLGLSPDLVVCRCSNPLDTSVKEKISMFCHVEPEQVICVHDVSSIYRVPLLLEEQGVVDYFLRRLDL-----PIERQSR--KMLMKWKEMADRYDRLLETCSIALVGKYTKFSDSYASVIKALEHSALAINHKLEIKYIDSTDLEPSTLQEEPVRYHEAWQKLCSAHGVLVPGGFGVRGTEGKIQAIAWARKQKKPFLGVCLGMQLAVVEFSRNVLGWQDANSTEFDPKT----SHPVVIDMPEHNPGQMGGTMRLGKRRTLFQTKN--SVMRKLYGDTDYLEERHRHRFEVNPVLKKCLEEQGLKFVGQDVEGERMEIVELEDHPFFVGVQYHPEFLSRPIKPSPPYFGLLLASVGRLPHYLQKGCRLSPR---DTYSDRS----GSSSPDSEITELKFPSISQD-----------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P17812-1", "uniprot_id": "PYRG1_HUMAN", "id": "P17812-1", "name": "CTP synthase 1", "aln": "-------------------------MKYILVTGGVISGIGKGIIASSVGTILKSCGLHVTSIKIDPYINIDAGTFSPYEHGEVFVLDDGGEVDLDLGNYERFLDIRLTKDNNLTTGKIYQYVINKERKGDYLGKTVQVVPHITDAIQEWVMRQALIPVDEDGLEPQVCVIELGGTVGDIESMPFIEAFRQFQFKVKRENFCNIHVSLVPQPSSTGEQKTKPTQNSVRELRGLGLSPDLVVCRCSNPLDTSVKEKISMFCHVEPEQVICVHDVSSIYRVPLLLEEQGVVDYFLRRLDL-----PIERQPR--KMLMKWKEMADRYDRLLETCSIALVGKYTKFSDSYASVIKALEHSALAINHKLEIKYIDSADLEPITSQEEPVRYHEAWQKLCSAHGVLVPGGFGVRGTEGKIQAIAWARNQKKPFLGVCLGMQLAVVEFSRNVLGWQDANSTEFDPTT----SHPVVVDMPEHNPGQMGGTMRLGKRRTLFQTKN--SVMRKLYGDADYLEERHRHRFEVNPVWKKCLEEQGLKFVGQDVEGERMEIVELEDHPFFVGVQYHPEFLSRPIKPSPPYFGLLLASVGRLSHYLQKGCRLSPR---DTYSDRS----GSSSPDSEITELKFPSINHD-----------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6PEI7-1", "uniprot_id": "PYRG1_DANRE", "id": "Q6PEI7-1", "name": "CTP synthase 1", "aln": "-------------------------MKYILVTGGVISGIGKGIIASSVGTILKSCGLHVTAIKIDPYINIDAGTFSPYEHGEVFVLDDGGEVDLDLGNYERFLDIRLTKDNNLTTGKIYQSVINKERRGDYLGKTVQVVPHITDAIQEWVMRQAKIPVDDDDVEPQVCVIELGGTVGDIESMPFVEAFRQFQFKVKRENFCNIHVSLVPQPSATGEQKTKPTQNSVRELRGLGLSPDLIMCRCSTPLDNSVKEKISMFCHVEPEQVICVHDVSSIYRVPLLLEDQGVVGYFCRRLNL-----PIENRPR--KMLAKWKEMSDRSDRLLEQCSIALVGKYTKFSDSYASVIKALEHSALAISHKLEVKYVDSADLEPSMLQEEPVKYHEAWQKLCSSDGILVPGGFGVRGTEGKIQAINWARKQKKPFLGVCLGMQLAVCEFARNMLDWTDANSTEFDPET----KHPVVIDMPEHNPGQMGGTMRLGKRRTIFKNKS--SILRKLYGDVDYVEERHRHRFEVNPELKHHFEEKGFRFVGQDVEGERMEVIEMDDHPYFVGVQYHPEFTSRPIKPSPPYLGLLLAAAGRLQSYLQKGCRLSPR---DAYSDRS----GSSSPDLEIADLKLRSIAQE-----------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0AC58HG78-1", "uniprot_id": "A0AC58HG78_DANRE", "id": "A0AC58HG78-1", "name": "CTP synthase", "aln": "MKIVFTSEPCPINHCLSYIDRCCCIMKYILVTGGVISGIGKGIIASSVGTILKSCGLHVTSIKIDPYINIDAGTFSPYEHGEVFVLDDGGEVDLDLGNYERFLDIRLTRDNNLTTGKIYQSVINKERRGDYLGKTVQVVPHITDAIQEWVMRQAKVSVDDDGIEPEVCVIELGGTVGDIESMPFIEAFRQFQFKVKRENFCNIHVSLVPQPNSTGEQKTKPTQNSVRELRGLGLSPDLIVCRCSTPLDTAVKEKISMFCHVEPEQVICIHDVSSIYRVPLLLEDQGMVHYFCRRLDL-----PIQMRPR--QMLRKWKEMSDRSDRLLEQTSIALVGKYTKLSDSYASVIKALEHSALAINYKLEVKYIDSAYLEPAALQDEPVKYHEAWQKLCSADGVLVPGGFGVRGTEGKIQAINWARKQKKPFLGVCLGMQLAVCEFARNVLGWEDANSTEFDPET----KHPVVIEMPEHNPGQMGGTMRLGKRRTLFKSTP--SILRKLYGDAEYVDERHRHRFEVNPELKHHFEDRGFRFVGQDLEGERMEIIELEDHTYFVGVQYHPEFTSRPIKPSPPYFGLLLAASGKLQNYLQKGCRLSPR---DAYSDRS----GTSSPDSEISEFKFPSLS-------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VUL1-1", "uniprot_id": "PYRG_DROME", "id": "Q9VUL1-1", "name": "CTP synthase", "aln": "-------------------------MKYILVTGGVISGVGKGVIASSFGTLLKSCGLDVTSIKIDPYINIDAGTFSPYEHGEVYVLDDGAEVDLDLGNYERFLDVTLHRDNNITTGKIYKLVIEKERTGEYLGKTVQVVPHITDAIQEWVERVAQTPVQ-GSSKPQVCIVELGGTIGDIEGMPFVEAFRQFQFRVKRENFCLAHVSLVPLPKATGEPKTKPTQSSVRELRGCGLSPDLIVCRSEKPIGLEVKEKISNFCHVGPDQVICIHDLNSIYHVPLLMEQNGVIEYLNERLQL-----NIDMSKRT-KCLQQWRDLARRTETVRREVCIAVVGKYTKFTDSYASVVKALQHAALAVNRKLELVFIESCLLEEETLHSEPSKYHKEWQKLCDSHGILVPGGFGSRGMEGKIRACQWARENQKPLLGICLGLQAAVIEFARNKLGLKDANTTEIDPNT----ANALVIDMPEHHTGQLGGTMRLGKRITVFSDGP--SVIRQLYGNPKSVQERHRHRYEVNPKYVHLLEEQGMRFVGTDVDKTRMEIIELSGHPYFVATQYHPEYLSRPLKPSPPFLGLILASVDRLNQYIQRGCRLSPRQLSDASSDEEDSVVGLAGATKSLSSLKIPITPTNGISKSCNGSISTSDSEGACGGVDPTNGHK", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P38627-1", "uniprot_id": "URA8_YEAST", "id": "P38627-1", "name": "CTP synthase 2", "aln": "-------------------------MKYVVVSGGVISGIGKGVLASSTGMLLKTLGLKVTSIKIDPYMNIDAGTMSPLEHGECFVLDDGGETDLDLGNYERYLGITLSRDHNITTGKIYSHVISRERRGDYLGKTVQIVPHLTNAIQDWIQRVSKIPVDDTGLEPDVCIIELGGTVGDIESAPFVEALRQFQFEVGRENFALIHVSLVP--VIHGEQKTKPTQAAIKDLRSLGLIPDMIACRCSEELNRSTIDKIAMFCHVGPEQVVNVHDVNSTYHVPLLLLKQHMIDYLHSRLKLGEVPLTLEDKERGSQLLTNWENMTKNLDDSDDVVKIALVGKYTNLKDSYLSVTKSLEHASMKCRRQLEILWVEASNLEPETQEVDKNKFHDSWNKLSSADGILVPGGFGTRGIEGMILAAKWARESGVPFLGVCLGLQVAAIEFARNVIGRPNSSSTEFLDETLLAPEDQVVIYMPEIDKEHMGGTMRLGLRPTIFQPNSEWSNIRKLYGEVNEVHERHRHRYEINPKIVNDMESRGFIFVGKDETGQRCEIFELKGHPYYVGTQYHPEYTSKVLEPSRPFWGLVAAASGTLGEVIKD----------------------INLSEGNENE--------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P28274-1", "uniprot_id": "URA7_YEAST", "id": "P28274-1", "name": "CTP synthase 1", "aln": "-------------------------MKYVVVSGGVISGIGKGVLASSTGMLMKTLGLKVTSIKIDPYMNIDAGTMSPLEHGECFVLDDGGETDLDLGNYERYLGVTLTKDHNITTGKIYSHVIAKERKGDYLGKTVQIVPHLTNAIQDWIERVAKIPVDDTGMEPDVCIIELGGTVGDIESAPFVEALRQFQFKVGKENFALIHVSLVP--VIHGEQKTKPTQAAIKGLRSLGLVPDMIACRCSETLDKPTIDKIAMFCHVGPEQVVNVHDVNSTYHVPLLLLEQKMIDYLHARLKLDEISLTEEEKQRGLELLSKWKATTGNFDESMETVKIALVGKYTNLKDSYLSVIKALEHSSMKCRRKLDIKWVEATDLEPEAQESNKTKFHEAWNMVSTADGILIPGGFGVRGTEGMVLAARWARENHIPFLGVCLGLQIATIEFTRSVLGRKDSHSAEFYPD--IDEKNHVVVFMPEIDKETMGGSMRLGLRPTFFQNETEWSQIKKLYGDVSEVHERHRHRYEINPKMVDELENNGLIFVGKDDTGKRCEILELKNHPYYIATQYHPEYTSKVLDPSKPFLGLVAASAGILQDVIEG----------------------KYDLEAGENKFNF-----------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ***::*:******:***::*** * ::*: **.**:******:******:** **** :*****.*.*********:*.: * :*:*:******. ** :** *:*******:***:*:***:*: * : .*: . :*:**::*****:****. **:**:*****.* :***. ****** ** ****** ::: **. ** **:: **.. :. . :**: **** *:**: :**:.* *:****: .: :: *: **.* : * : * :*. : . : **:*****::.*** ** *:*:*::: :*:: :::: ** . : ::*. *: :. :.*:*:***** ** ** : * ***:. *:**:***:* *. **:*. :. :: ::*: . :*: *** . :**:**** * *.*. * :::***: . :.******:*:** . :*..*: *** * * *:.*:..*.:::..*****: *: :.** *: **: *: . * :: . ", "identical_positions": 254, "similar_positions": 166, "identity": "38.2%" }, { "cls_id": "homologset.agr.MGI:1858305", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P70580-1", "uniprot_id": "PGRC1_RAT", "id": "P70580-1", "name": "Membrane-associated progesterone receptor component 1", "aln": "----MAAEDVVATGADP-SELEG------GGLLQEIFTSPLNLLLLGLCIFLLYKIVRGDQPGASGDNDDDEPPPLPRLKPRDFTPAELRRYDGVQ-DPRILMAINGKVFDVTKGRKFYGPEGPYGVFAGRDASRGLAT--FCLDKEALKDEYDD-LSDLTPAQQETLNDWDSQFTFKYHHVGKLLKEGEEPTVYSDDEEPK----DEAARKSD---------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O55022-1", "uniprot_id": "PGRC1_MOUSE", "id": "O55022-1", "name": "Membrane-associated progesterone receptor component 1", "aln": "----MAAEDVVATGADP-SELEG------GGLLHEIFTSPLNLLLLGLCIFLLYKIVRGDQPGASGDNDDDEPPPLPRLKRRDFTPAELRRFDGVQ-DPRILMAINGKVFDVTKGRKFYGPEGPYGVFAGRDASRGLAT--FCLDKEALKDEYDD-LSDLTPAQQETLSDWDSQFTFKYHHVGKLLKEGEEPTVYSDDEEPK----DETARKNE---------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O00264-1", "uniprot_id": "PGRC1_HUMAN", "id": "O00264-1", "name": "Membrane-associated progesterone receptor component 1", "aln": "----MAAEDVVATGADP-SDLES------GGLLHEIFTSPLNLLLLGLCIFLLYKIVRGDQPAASGDSDDDEPPPLPRLKRRDFTPAELRRFDGVQ-DPRILMAINGKVFDVTKGRKFYGPEGPYGVFAGRDASRGLAT--FCLDKEALKDEYDD-LSDLTAAQQETLSDWESQFTFKYHHVGKLLKEGEEPTVYSDEEEPK----DESARKND---------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VXM4-1", "uniprot_id": "Q9VXM4_DROME", "id": "Q9VXM4-1", "name": "", "aln": "MDSKVGADPSSAYDKEIGNNLNNDDSSFLGNIIREILYSPMNLALLAIICFLVYKIVRDRTEVPSVGVAKPSEPELPKIR-RDFTVKELRQYDGTQPDGRVLVAVNGSVYDVSKGRRFYGPGGPYATFAGRDASRNLAT--FSVVSID-KDEYDD-LSDLSAVEMDSVREWEMQFKEKYELVGKLLRKGEEPTNYDDDEDEENVNNDEQERKNLPKSKTETDDTKQEKESHILQSNVTNKNNAQDQATPSTDC", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q12091-1", "uniprot_id": "DAP1_YEAST", "id": "Q12091-1", "name": "Damage response protein 1", "aln": "------------------------------------MSFIKNLLFGGVKTSEDPTGLTGNGASNTNDSNKGSEP----VVAGNFFPRTLSKFNGHD-DEKIFIAIRGKVYDCTRGRQFYGPSGPYTNFAGHDASRGLALNSFDLDVIKDWDQPIDPLDDLTKEQIDALDEWQEHFENKYPCIGTLIP---EPGVNV---------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : ** : .: . : . : . . . * : :* * :::* : * ::::*:.*.*:* ::**:**** *** ***:****.** * : *: * *.**: : ::: :*: :* ** :*.*: ** ", "identical_positions": 43, "similar_positions": 44, "identity": "17.0%" }, { "cls_id": "homologset.agr.MGI:1858306", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q63769-1", "uniprot_id": "SRPX_RAT", "id": "Q63769-1", "name": "Sushi repeat-containing protein SRPX", "aln": "MGSPGLRPTLLLPQVLLLLLALLHVPPSQGFPGSGDSPLEDDGVWSSHSLYKDTPWCSPIKVKYGDVYCRAPPGGYYKTALGTRCDIRCRKGYELHGSSQLVCQSNRRWSDKVICKQKRCPTLTMPANGGFKCVDGAYFNSRCEYYCSPGYTLKGERTVTCMDNKAWSGRPASCVDMEPPRIKCPSVKERIAEPNKLTVRVSWETPEGRDTADGILTDVILRGLPPGSNFPEGDHKIEYTVYDRAENKGTCKFRVKVRVRRCGKLNAPENGYMKCSSDGDNYGATCEFSCIGGYELQGSPARVCQSNLAWSGTEPSCAAMNVNVGVRTAAALLDQFYEKRRLLIVSTPTARNLLYRLQLGMLQQAQCGLDLRHITVVELVGVFPTLIGRIRAKIMPPALALQLRLLLRIPLYSFSMVLVDKHGMDKERYVSLVTPMALFNLIDTFPLRKEEMILQAEMGQSCNT", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9R0M3-1", "uniprot_id": "SRPX_MOUSE", "id": "Q9R0M3-1", "name": "Sushi-repeat-containing protein SRPX", "aln": "MGSPGLRPELLLPQVLPLLLALLHVLPSQGFPGSGDSPLEDDGVWYSHSLYKDTPWCSPIKVKYGDVYCRAPPGGYYKTALGTRCDIRCRKGYELHGSSQLICQSNKRWSDKVICKQKRCPTLTMPANGGFKCVDGAYFNSRCEYYCSPGYTLKGERTVTCMDNKAWSGRPASCVDLEPPRIKCPSVKERIAEPNKLTVRVSWESPEGRDTADGILTDVILKGLPPGSNFPEGDHKIEYTVYDRAENKGTCKFRVKVRVRRCGKLNAPENGYMKCSSDGDNYGATCEFSCIGGYELQGSPARVCQSNLAWSGTEPSCAAMNVNVGVRTAAALLDQFYEKRRLLIVSTPTARNLLYRLQLGMLQQAQCGLDLRHVTVVELVGVFPTLIGRIRAKIMPPALALQLRLLLRIPLYSFSMVVVDKHGMDKERYVSLVTPMALFNLIDTFPLRKEEMILQAEMGQTCNV", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P78539-1", "uniprot_id": "SRPX_HUMAN", "id": "P78539-1", "name": "Sushi repeat-containing protein SRPX", "aln": "MGSPAHRPALLLLLPPLLLLLLLRVPPSRSFPGSGDSPLEDDEVGYSHPRYKDTPWCSPIKVKYGDVYCRAPQGGYYKTALGTRCDIRCQKGYELHGSSLLICQSNKRWSDKVICKQKRCPTLAMPANGGFKCVDGAYFNSRCEYYCSPGYTLKGERTVTCMDNKAWSGRPASCVDMEPPRIKCPSVKERIAEPNKLTVRVSWETPEGRDTADGILTDVILKGLPPGSNFPEGDHKIQYTVYDRAENKGTCKFRVKVRVKRCGKLNAPENGYMKCSSDGDNYGATCEFSCIGGYELQGSPARVCQSNLAWSGTEPTCAAMNVNVGVRTAAALLDQFYEKRRLLIVSTPTARNLLYRLQLGMLQQAQCGLDLRHITVVELVGVFPTLIGRIGAKIMPPALALQLRLLLRIPLYSFSMVLVDKHGMDKERYVSLVMPVALFNLIDTFPLRKEEMVLQAEMSQTCNT", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "****. ** *** *** **:* **:.************ * **. ********************** ****************:********* *:****:****************:****************************************************:***************************:****************:***************:*********************:*******************************************************:*********************************************************:**************** **************************:*************** *:****************:*****.*:**.", "identical_positions": 425, "similar_positions": 22, "identity": "91.59%" }, { "cls_id": "homologset.agr.MGI:1858308", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q5U2X5-1", "uniprot_id": "ACK1_RAT", "id": "Q5U2X5-1", "name": "Activated CDC42 kinase 1", "aln": "--------------------------MQPEEGTGWLLELLSEVQLQQYFLRLRDDLNITRLSHFEYVKNEDLEKIGMGRPGQRRLWEAVKRRKAMCKRKSWMSK-------VFSGKRQEAEFPSHHSQSTFRKPSPTPGGLAGEGTLQSLTCLIGEKDLRLLEKLGDGSFGVVRRGEWDA-PAGKTVSVAVKCLKPDVLSQPEAMDDFIREVNAMHSLDHRNLIRLYGVVLTPPMKMVTELAPLGSLLDRLRKHQGHFLLGTLSRYAVQVAEGMGYLESKRFIHRDLAARNLLLATRDLVKIGDFGLMRALPQNDGHYVMQEHRKVPFAWCAPESLKTRTFSHASDTWMFGVTLWEMFTYGQEPWIGLNGSQILHKIDKEGERLPRPEDCPQDIYNVMVQCWAHKPEDRPTFVALRDFLLEAQPTDMRALQDFEEPDKLHIQMNDVITVIEGRAENYWWRGQNTRTLCVGPFPRNVVTSVAGLSAQDISQPLQNSFIHTGHGDSDPRHCWG----FPDRIDELYLGNPMDPPDLLSVELSTSRPTQHLGRMK----------------------------------------KPTYDPVSEDPDPLSSDFKRLGLRKPALPRG--LWLAKPSARVPGTKAGRSSGG----EVTLIDFGEEPVAPTPRP------CAPSLAQLAMD-ACSLLDKTPPQSPTRALPRPLHPTPVVDWDARPLPPPPAYDDVAQD---EDDFEVCSINSTLVSAGLPTGPSQGETNYAFVPEQAQLPPALEDNLFLPPQGGGQPPSSAQTAEIFQALQQECMRQLQVPTG----QLTPSPTPG-------------GDDKPQVPPRVPIPP-RPTRPRVGLSPAPLGEEE--ASRWPGPSSPPRVPPRE-PLSPQGSRTPSP----------LVPPGSSP-----------LPHRLSSSPGKTMPTTQSFASDPKYATPQVIQAPG----PRAGPCILPIVRDGRKVSSTHYYLLPERPPYLERYQRFLREAQSPEEPAALPVPPLLPPPSTPAPAAPTATVRPMPQAAPDPKANFSTNNSNPGAQP---PSLRASARLPQRGCPGDGQEAARPADKVQMLQAMVHGVTTEECQAALRSHSWSIQRAAQYLKVEQLFGLGLRPRVECHKVLEMFDWNLEQAGCHLLGSCGPAHHKR", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O54967-1", "uniprot_id": "ACK1_MOUSE", "id": "O54967-1", "name": "Activated CDC42 kinase 1", "aln": "--------------------------MQPEEGTGWLLELLSEVQLQQYFLRLRDDLNITRLSHFEYVKNEDLEKIGMGRPGQRRLWEAVKRRKAMCKRKSWMSK-------VFSGKRLEAEFPSQHSQSTFRKPSPTPGSLPGEGTLQSLTCLIGEKDLRLLEKLGDGSFGVVRRGEWDA-PAGKTVSVAVKCLKPDVLSQPEAMDDFIREVNAMHSLDHRNLIRLYGVVLTLPMKMVTELAPLGSLLDRLRKHQGHFLLGTLSRYAVQVAEGMAYLESKRFIHRDLAARNLLLATRDLVKIGDFGLMRALPQNDDHYVMQEHRKVPFAWCAPESLKTRTFSHASDTWMFGVTLWEMFTYGQEPWIGLNGSQILHKIDKEGERLPRPEDCPQDIYNVMVQCWAHKPEDRPTFVALRDFLLEAQPTDMRALQDFEEPDKLHIQMNDVITVIEGRAENYWWRGQNTRTLCVGPFPRNVVTSVAGLSAQDISQPLQNSFIHTGHGDSDPRHCWG----FPDRIDELYLGNPMDPPDLLSVELSTSRPTQHLGRVKREPPPRPPQP-------------------------AIFTQKTTYDPVSEDPDPLSSDFKRLGLRKPALPRG--LWLAKPSARVPGTKADRSSGG----EVTLIDFGEEPVVPTPRP------CAPSLAQLAMD-ACSLLDKTPPQSPTRALPRPLHPTPVVDWDARPLPPPPAYDDVAQD---EDDFEVCSINSTLVGAGLPAGPSQGETNYAFVPEQAQMPPALEDNLFLPPQGGGKPPSSVQTAEIFQALQQECMRQLQVPTG----QLTPSPTPG-------------GDDKPQVPPRVPIPP-RPTRPRVELSPAPSGEEE--TSRWPGPASPPRVPPRE-PLSPQGSRTPSP----------LVPPGSSP-----------LPHRLSSSPGKTMPTTQSFASDPKYATPQVIQAPG----PRAGPCILPIVRDGRKVSSTHYYLLPERPPYLERYQRFLREAQSPEEPAALPVPPLLPPPSTPAPAAPTATVRPMPQAAPDPKANFSTNNSNPGARP---PSLRAAARLPQRGCPGDGQEAARPADKVQMLQAMVHGVTTEECQAALQSHSWSVQRAAQYLKVEQLFGLGLRPRVECHKVLEMFDWNLEQAGCHLLGSCGPAHHKR", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q07912-1", "uniprot_id": "ACK1_HUMAN", "id": "Q07912-1", "name": "Activated CDC42 kinase 1", "aln": "--------------------------MQPEEGTGWLLELLSEVQLQQYFLRLRDDLNVTRLSHFEYVKNEDLEKIGMGRPGQRRLWEAVKRRKALCKRKSWMSK-------VFSGKRLEAEFPPHHSQSTFRKTSPAPGGPAGEGPLQSLTCLIGEKDLRLLEKLGDGSFGVVRRGEWDA-PSGKTVSVAVKCLKPDVLSQPEAMDDFIREVNAMHSLDHRNLIRLYGVVLTPPMKMVTELAPLGSLLDRLRKHQGHFLLGTLSRYAVQVAEGMGYLESKRFIHRDLAARNLLLATRDLVKIGDFGLMRALPQNDDHYVMQEHRKVPFAWCAPESLKTRTFSHASDTWMFGVTLWEMFTYGQEPWIGLNGSQILHKIDKEGERLPRPEDCPQDIYNVMVQCWAHKPEDRPTFVALRDFLLEAQPTDMRALQDFEEPDKLHIQMNDVITVIEGRAENYWWRGQNTRTLCVGPFPRNVVTSVAGLSAQDISQPLQNSFIHTGHGDSDPRHCWG----FPDRIDELYLGNPMDPPDLLSVELSTSRPPQHLGGVK----------------------------------------KPTYDPVSEDQDPLSSDFKRLGLRKPGLPRG--LWLAKPSARVPGTKASRGSGA----EVTLIDFGEEPVVPALRP------CAPSLAQLAMD-ACSLLDETPPQSPTRALPRPLHPTPVVDWDARPLPPPPAYDDVAQD---EDDFEICSINSTLVGAGVPAGPSQGQTNYAFVPEQARPPPPLEDNLFLPPQGGGKPPSSAQTAEIFQALQQECMRQLQAPAG----SPAPSPSPG-------------GDDKPQVPPRVPIPP-RPTRPHVQLSPAPPGEEE--TSQWPGPASPPRVPPRE-PLSPQGSRTPSP----------LVPPGSSP-----------LPPRLSSSPGKTMPTTQSFASDPKYATPQVIQAPG----PRAGPCILPIVRDGKKVSSTHYYLLPERPSYLERYQRFLREAQSPEEPTPLPVPLLLPPPSTPAPAAPTATVRPMPQAALDPKANFSTNNSNPGARP---PPPRATARLPQRGCPGDGPEAGRPADKIQM--AMVHGVTTEECQAALQCHGWSVQRAAQYLKVEQLFGLGLRPRGECHKVLEMFDWNLEQAGCHLLGSWGPAHHKR", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9PXR5-1", "uniprot_id": "A0A8M9PXR5_DANRE", "id": "A0A8M9PXR5-1", "name": "Activated CDC42 kinase 1", "aln": "MRRFDKLKKSFPFLAHFHVYRKLGSSMQCEEGTEWLLELLMEVQLQQYFLRIRDELNITRLSHFDYVKNEDLEKIGMGRPGQRRLWEAVKRRKTMCKRKSWMSK-------VFSGKRPEGDFNPQP-ASTFRKLSPTP--PLVDGQQQALTCLISEKDLALFEKLGDGSFGVVKRGEWFT-PNGKVLNVAVKCLKTDVLNQPDALDDFIREVNAMHSLDHQNLIRLYGVVLTHPMKMVTELAPLGSMLDRLRKTLGHFLISTLCQYTIQISNGMGYLESKRFIHRDLAARNILLASSEQVKIGDFGLMRALPKNDDHYVMQEHRKVPFAWCAPESLKTRTFSHATDTWMFGVTLWEMFTYGQEPWLGLNGSQILHKIDKEGERLPKPEDCPQDLYNVMMQCWAQKPDDRPTFVALREFLVETMPTDMRALQDFDEPDKLQIQMDDVITIIEGRAENYWWRGQNKRTLKVGQFPRNTVTSVAGLSAHDISRPLKNSFIHTGHGDTNPHRCWG----FPDRIDDLYLGNPMDPPDVLGLDLNSARPTQLPGRAKKEPPPRPPQPPLLVKSKCGPSVQFKHCSCPLCSLLAPLIKEPCYDAVAEDEEQTYSALRRLSLKKKGLKLKPAAWVSATRLGDRSSYGARTPGGSTPTEVSLIDFGEEYPSATSSPSPVAEIQIPTLAKLALD-AENILDRTPPQSPSRTLPRPLHPTPVVDWDARPLPPPPAYDDVAQD---EDDFEVSSINSAERADGEPCSP------HAPCTPTGESKPHVEDNLFLPCRLSN-ACTFSQSAEIFQELQQECMRHLKVPVN----STSPGLEPHRQI------VLTFSEDKPQIPPRIPIPP-RPVKRAGGDYSRLSGDLSPVFGNEDDKERPPQIPPRD-PFSQPGSRTPSPHVGSPQTRSSLCSAASIY-----------GSSYLSTSPAKLMPTTQSFASDPKYAAPKVIQAQGKDKEPTKGPCILPIVRDGKKVSNTHYYLLPERPPYLDRYDKFFREAECGEE----------------KKQVNTATVKPMVHQHGELKSNFSSNNNSSLTASGFRGGLKSSFSLCRVSSDGSFNKADSNHDRVRLVQEAVHGVTIEECLTALQNHSWNVQKAVHYLKVEQLFCLGLKTRLECQQILEMYDWNLELASTQMLDSYGSVKLRR", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8M3APA4-1", "uniprot_id": "A0A8M3APA4_DANRE", "id": "A0A8M3APA4-1", "name": "Activated CDC42 kinase 1", "aln": "------MAALSDYQRHYNVKDEP--DMQSDEGTEWLLELLTDVQLQQYFQRIRDELNVTRLSHFDYVKTEDLEKIGMGRPGQRRLWEAVKRRRAMCKRKSWMSKSLCLGQQVFTGKRPDSDS---QTPEVFRSSSPSS--APPDGQPTDLTCLISERDLTLYEKLGDGSFGVVKRGEWQA-PSGRVLSVAVKCLKTDLLDQGEGLDDFIREVNAMHSLNHHNLIRLYGCVLTHPMKMVTELAPLGSLLDRLRKRQGHILISVLCHYTVQIACGMAYLESRRFIHRDLAARNILLASNDLIKIGDFGLMRALPKNDDHYVMQEHHKVPFAWCAPESLKTRTFSHASDTWMFGVTLWEMFTHGQEPWVGLNGSQILHKIDREGERLIKPEDCPQDIYNVMLQCWSPKPEDRPTFVSLRDFLVETMPTDMRALQDFDEPDKLKIHANDIITIIEGRAENYWWRGQNRQTMKVGQFPRNVVTSVAGLSAQDISRPLKHSFIHTGHGDTDPHRSWG----APDKIDDLYLGNPMDPPDVLGLDSNTAKPTKLPNRAKKQPPPRPPKP-------------------------AVLLKKPFYDSVLDDDD--DDDLIVTGVKKLSLKTP-----TYLGLRLRPWESTSPSDR--LCEVSLIDFGDDSFSSTSPS-PITEIPNPSTAKPPLSYAASILDMAPPQSPNQALPNPMHPTPVVDWDMRPLPPLPAYDEVAIECAEQEDIEVSSINASAAQEDAVYEQTP-----SEEDINNDGKRNVEDNLFLPSKRPEESHSFSQSADIFKELQREVMVKLRVPPSGRSLPSSPLPTPSVLTPHRQIILPSSYEDKPQIPPRIPIPPMRPSKRTGIYGSRLSVSLG---ENEDGSRCPPQIPPRDHALSQPNSRAPSP----------MVPQSGSPQQRSSLCCVGSLGSCLSPSSYSSAPSSSSTTSSTSTTTSSQYGSTEVSQNPAKSPCILPIVHGGVKASSTHYYLLPEKPAYLDKYEKFFNSEGNDEK-----------------RTTNMATVRPMVQQQGNKSNASPSHTSNSGTSS-------------SLAWPSSSQAGSYSRVTLQQVQEAVHGVTVEECQTALQAHNWNAQEAVKYLKVEQLFRLGLKTRPECMETLQRCGWNLEQASTQMLDSYGPSRHRF", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VZI2-1", "uniprot_id": "ACK_DROME", "id": "Q9VZI2-1", "name": "Activated Cdc42 kinase Ack", "aln": "------------------MTSTSAVDGGLGSETAWLEDLLREVQLEQFLDRIRDDLQVTRLAHFDYVLPDDLERCGLGKPAIRRLMEAVRKKKAHQWRKNILSK-------LIGGGKQ---------PSSKKQSSAAR--ESSQGNGTQLTCLIHEKDITMGLKLGDGSFGVVRRGEWSASPAGKVIPVAVKVLKSDNLTQPGIIDDFFREVQAMHALDHANLVRLYGVVLSQPMMMITELAERGSLLDTLRKQCRHTSLTIIWNWSVQIVTGMAYLEQKRFLHRDLACRNVLLAAGNKIKIGDFGLMRALPQEDDCYVMSEHKKVPFPWCAPESLRFRQFSHASDTWMFGVTLWEMFSFGEDPWVGLNGSQILRKIDREGERLHQPDACPPDVYAMMLQCWDKTPAERPTFAALKEYLASMSPPVMRASRSHHESKGLQIEPGDTIAIIDGRHELKLIKGQNQRTFDIGIFPRNLLEQRK---VGAAGDVVMRSSVGNGSSSSPFGFCWGGAAAMANGDDRQRKCASMTNQPHAKERKSTSSKQFAYNKLVNDSATGLQRRN------------------------AVKHKGVVVGPQRPPPPQFQQEGILIDISPDMRPIAEAGTGGAKGAGDSSSLQADSSFCILDAPIDVPTYAGSSGSGDLNVS-----PTYYNEQPQFDFDPAKMTASPGRLQPPPYQMPPTYSNTMEFVQKRDLHQQQLATPVRE---RDPFDTTNVETTVALYSNFNQSLEA----ASPPAPIYNSPSVRKSLFGGSKSNKENIPALESAAMQLNLSNLTLERHDATCIQPVEPVPAPPGDGVLLDKS----FIAELEKDMYSNGQNRAQEEYQRNSTQMYASKDMVYKQNLTPLKNGAAPGSVHSNHSSPSSTASPKQNN-----------VEAAAAA------------AATTQSVVNRIWYEQVASTQSEYYAQPPTEQAEEQIYQNHRHQQQQQQELNHSFVAISNRVVAPKNNAYSSTASLYDAVAASTAGSTYYGQVPNGSGAVLYDEVTQDDYLRPTRPAPLAPPPLSAQQIQRRMEKMR-LQQQQQLDGAHQLYAPVPSDYGREQEKLQQLMQELGSSAVEQDVRNALRAASGDVGLATRHYKIDQLARLGVAGRPQCEQALQQTNWSLEVAAELLLNAG-------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . * ** :** :***:*:: *:**:*::***:**:** :***: *:*:*. *** ***::::: **. :** :: * : . :. *.: :* ***** *:*: : **********:**** : * *:.: **** **.* * * :***:***:***:*:* **:**** **: ** *:**** **:** *** * : : .:::*: **.***.:**:*****.**:***: : :************::*. ***.**:****.*******: * ****:*************:.*::**:********:***:***** :*: ** *:* :*:*** .* :****.:*:::* . *. *** :...*.. *:*. .* *::*:** * :*** :*: :* **** : . . . : .* : .* ..: .** .: * .* .:: . .. . .: . : : :. . : :. : :* : . * : .::: : . : .: :: .:::: . : :...** : . ::* : *.. : : .. .. :* . . . : . . * : ... . * * . .. .. : :.. : . : . .: :: : *:. .* . . : . ::* . : . . : ... :: **: . . *.:: *::** **: * :* : *: .*.** *. :*.: ", "identical_positions": 262, "similar_positions": 252, "identity": "22.15%" }, { "cls_id": "homologset.agr.MGI:1858313", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I6A3Z5-1", "uniprot_id": "A0A8I6A3Z5_RAT", "id": "A0A8I6A3Z5-1", "name": "SUMO-activating enzyme subunit 2", "aln": "--------------------------------------------------IDLDTIDVSNLNRQFLFQKKHVGRSKAQVAKESVLQFHPQANIEAHHDSIMNPDYNVEFFRQFILVMNALDNRAARNHVNRMCLAADVPLIESGTAGYLGQVTTIKKGVTECYECHPKPTQRTFPGCTIRNTPSEPIHCIVWAK-YLFNQLFGEEDADQEVSPDRADPEAA------------------WEPTEAEARARASNEDGDIKRISTKEWAKSTGYDPVKLFTK----------LFKDDIRYLLTMDKLWRKRKPPVPLDWAEVQSQGEEANAD-QQSEPQLGLKDQQVLDVKSYASLFSKSIETLRVRLAEKGDGAELIWDKDDPPAMDFVTSAANLRMHIFSMNMKSRFDIKSMAGNIIPAIATTNAVIAGLIVLEGLKIL-------SGKIDQCRTIFLNKQPNPRKKLLVP-CALDPPNTNCYVCASKPEVTVRLNVHKVTVLTLQDKIVKEKFAMVAP-DVQIEDGKGTILISSEEGETEANNPKKLSDFGIRNGSRLQADDFLQDYTLLINILHSEDLGKDVEFEVVGDT--------PEKVGPKQAEDAAKSIANGSDDG------AQPSTS--------TAQEQDDVLIVDSDEEGP------SNSADGSRDDRT-RKRK-------------LEENEGAST-----KKSRLEQV---EDQDDVIALD", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9Z1F9-1", "uniprot_id": "SAE2_MOUSE", "id": "Q9Z1F9-1", "name": "SUMO-activating enzyme subunit 2", "aln": "----MALSRGLPRELAEAVSGGRVLVVGAGGIGCELLKNLVLTGFSHIDLIDLDTIDVSNLNRQFLFQKKHVGRSKAQVAKESVLQFHPQANIEAHHDSIMNPDYNVEFFRQFILVMNALDNRAARNHVNRMCLAADVPLIESGTAGYLGQVTTIKKGVTECYECHPKPTQRTFPGCTIRNTPSEPIHCIVWAK-YLFNQLFGEEDADQEVSPDRADPEAA------------------WEPTEAEARARASNEDGDIKRISTKEWAKSTGYDPVKLFTK----------LFKDDIRYLLTMDKLWRKRKPPVPLDWAEVQSQGE-ANAD-QQNEPQLGLKDQQVLDVKSYASLFSKSIETLRVHLAEKGDGAELIWDKDDPPAMDFVTSAANLRMHIFSMNMKSRFDIKSMAGNIIPAIATTNAVIAGLIVLEGLKIL-------SGKIDQCRTIFLNKQPNPRKKLLVP-CALDPPNTNCYVCASKPEVTVRLNVHKVTVLTLQDKIVKEKFAMVAP-DVQIEDGKGTILISSEEGETEANNPKKLSDFGIRNGSRLQADDFLQDYTLLINILHSEDLGKDVEFEVVGDS--------PEKVGPKQAEDAAKSIANGSDDG------AQPSTS--------TAQEQDDVLIVDSDEEGP------SNSTDCSGDDKA-RKRK-------------LEENEAAST-----KKCRLEQM---EDPDDVIALD", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9UBT2-1", "uniprot_id": "SAE2_HUMAN", "id": "Q9UBT2-1", "name": "SUMO-activating enzyme subunit 2", "aln": "----MALSRGLPRELAEAVAGGRVLVVGAGGIGCELLKNLVLTGFSHIDLIDLDTIDVSNLNRQFLFQKKHVGRSKAQVAKESVLQFYPKANIVAYHDSIMNPDYNVEFFRQFILVMNALDNRAARNHVNRMCLAADVPLIESGTAGYLGQVTTIKKGVTECYECHPKPTQRTFPGCTIRNTPSEPIHCIVWAK-YLFNQLFGEEDADQEVSPDRADPEAA------------------WEPTEAEARARASNEDGDIKRISTKEWAKSTGYDPVKLFTK----------LFKDDIRYLLTMDKLWRKRKPPVPLDWAEVQSQGEETNASDQQNEPQLGLKDQQVLDVKSYARLFSKSIETLRVHLAEKGDGAELIWDKDDPSAMDFVTSAANLRMHIFSMNMKSRFDIKSMAGNIIPAIATTNAVIAGLIVLEGLKIL-------SGKIDQCRTIFLNKQPNPRKKLLVP-CALDPPNPNCYVCASKPEVTVRLNVHKVTVLTLQDKIVKEKFAMVAP-DVQIEDGKGTILISSEEGETEANNHKKLSEFGIRNGSRLQADDFLQDYTLLINILHSEDLGKDVEFEVVGDA--------PEKVGPKQAEDAAKSITNGSDDG------AQPSTS--------TAQEQDDVLIVDSDEEDS------SNNADVSEEERS-RKRK-------------LDEKENLSA-----KRSRIEQK---EELDDVIALD", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q7SXG4-1", "uniprot_id": "SAE2_DANRE", "id": "Q7SXG4-1", "name": "SUMO-activating enzyme subunit 2", "aln": "---MAELVGPLRKQLADSLSSCRVLVVGAGGIGCELLKNLVLTGFKNIEVIDLDTIDVSNLNRQFLFQKKHVGKSKAQVAKESVLRFCPSANITAYHDSIMNPDYNVEFFRNFQLVMNALDNRAARNHVNRMCLAADIPLIESGTAGYLGQVTVIKKGQTECYECQPKPTQKTFPGCTIRNTPSEPIHCIVWAK-YLFNQLFGEEDADQEVSPDTADPEAA------------------WNPADAAARATASDQDGDIKRVSTKEWARSTGYDPIKLFNKVSALSQTSPYLFKDDIMYLLTMDKLWKKRKAPLPLEWEEINQLGS------QEQVIGSGLKDQQVLGVQGYAQLFQHSVETLRSQLKEKGDGAELVWDKDDPPAMDFVTAASNLRMNVFSMNMKSRFDVKSMAGNIIPAIATTNAVIAGLIVLEALKIL-------NSDFEQCRTIFLNKQPNPRKKLLVP-CALDPPNASCYVCASKPEVTVKLNVHKTMVQALQDKILKEKFGMVAP-DVQIEDGKGTILISSEEGETEANNNKFLSDFGIRNGSRLQADDFLQDYTLLVNVIHSEELEKDVEFEVVGDA--------PDKAPAPSAPEEGKNIANGNKDS------AQPSTSSK------AAVEDDDVLLVDSDEEPS------SSTMDTESSNRK-RKHH-------------DAETDDASS-----KRKRLDQQPADDDDEDIIALD", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q7KUA4-1", "uniprot_id": "Q7KUA4_DROME", "id": "Q7KUA4-1", "name": "SUMO-activating enzyme subunit", "aln": "--MAAAINGVFPPTLQELVKKSKVLVVGAGGIGCEVLKNLVLSGFTDIEIIDLDTIDLSNLNRQFLFHREHVGKSKARVARESALSFNPDAKITAYHDSVTSTDYGVNFFKKFDLVLSALDNRAARNHVNRMCLNADVPLIESGTAGYNGQVELIKRGLTQCYECTPKDKQRSFPGCTIRNTPSEPIHCIVWAK-HLFNQLFGESLEDEDISPDAADPDAKEKDGGDGNGEPKGDGKEKGEESKEEKEAKEDTANGNIMRINTRQWAKDCNYDAGKLFNK----------FFNEDITYLLRMSNLWKTRKAPVPVQWDTLLPEGS------SGDQKDVAKQHHKVWSIEECAQVFANSLKELSANFLKLEGDDTLAWDKDDQPAMDFVAACANVRSHIFDIERKSRFEIKSMAGNIIPAIATTNAITAGISVMRAFKVL-------EAKWEQCKAVYARLRPNARNHFLVPDASLPGPNPNCHVCASDPAITLKIDTKRMRIKELRDEVLVKTLNMLNP-DVTVQS-NGSILISSEEGETECNDGKLLSELNIVDGVILKCDDFFQNYELSIIISHFDAERDENLFEVVADASQLKPKDEDQKEAVKDKEDEPKSAKKRSTNGEGDSKDDGPSTSKRSRPNEVVEEDDDDCLVIEEDEDQADVVVVATDKLSVQSPPKSGSKRKPCEVIEDEDITEILESSDDEPAGPTKCKRSRLDDS----NPVAVISID", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P52488-1", "uniprot_id": "UBA2_YEAST", "id": "P52488-1", "name": "Ubiquitin-activating enzyme E1-like", "aln": "MPRETSLVTIIGEDSYKKLRSSRCLLVGAGGIGSELLKDIILMEFGEIHIVDLDTIDLSNLNRQFLFRQKDIKQPKSTTAVKAVQHFNNSKLVPYQGNVMDISTFPLHWFEQFDIIFNALDNLAARRYVNKISQFLSLPLIESGTAGFDGYMQPIIPGKTECFECTKKETPKTFPVCTIRSTPSQPIHCIVWAKNFLFNQLFASETSGNEDDNNQD-----------------------WGTDDAEEIKRIKQETNELYELQKIIISRDASRIPEILN-K----------LFIQDINKLLAIENLWKTRTKPVPLSDSQIN-----------TPTKTAQSASNSVGTIQEQISNFINITQKLMDRYPKEQN--HIEFDKDDADTLEFVATAANIRSHIFNIPMKSVFDIKQIAGNIIPAIATTNAIVAGASSLISLRVLNLLKYAPTTKYTDLNMAFTAKASNLSQNRYLSNPKLAPPNKNCPVCSKVCRGVIKLSSDCLNKMKLSDFVVLIREKYSYPQDISLLDASNQRLLFDYD--FEDLNDRTLSEINLGNGSIILFSDEEGDTMIRKAIELFLDVDDELPCNTCSLP--------DVEVPLIKANNSPSKNEEEEKNEKG----ADVVAT-------TNSHGKDGIVILDDDEGE----------ITIDAEPINGSKKRP----------VDTEISEAPSN-----KRTKLVNEP---TNSDIVELD", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :******:*********:::.: :.*: .* ::. * . : : : . : :.:*.:* :::.**** ***.:**::. .:*********: * : * * *:*:** * . ::** ****.***:********* .******... .:: . : . . .:: .:.. ::. . . * * :* :** ** :.:**:.*. *:*:. : :.* :: * : : * . : . : :**** :::**::.:*:* ::*.: ** *::*.:*************: ** : .:::* . : . : .* :: :. * ** .* **:. .:::. . * * :: * *: : . .. *: . : * : : **::.: :* : .* : : : .: :. . . : . : .. : . : :: .*. ::::.** . *:: .: . *: :: : :: :*", "identical_positions": 137, "similar_positions": 189, "identity": "18.72%" }, { "cls_id": "homologset.agr.MGI:1858317", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O35093-1", "uniprot_id": "TIM23_RAT", "id": "O35093-1", "name": "Mitochondrial import inner membrane translocase subunit Tim23", "aln": "---MEGGGGSSNKSTGGLAGFFGAGGAGYSNADLAGVP------LTG-------MNPLSPYLNVDP--RYLVQDTDEFILPTGAN---KTRGRFELAFFTIGGCCMTGAAFGALNGLRLGLKETQSMPWSKPRNVQILNMVTRQGALWANTLGSLALLYSAFGVIIEKTRGAEDDFNTVAAGTMTGMLYKCTGG------LRGIARGGLAGLTLTSVYALYNNWEHMKGSLLQQSL---------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9WTQ8-1", "uniprot_id": "TIM23_MOUSE", "id": "Q9WTQ8-1", "name": "Mitochondrial import inner membrane translocase subunit Tim23", "aln": "---MEGGGRSSNKSTSGLAGFFGAGGAGYSNADLAGVP------LTG-------MNPLSPYLNVDP--RYLVQDTDEFILPTGAN---KTRGRFELAFFTIGGCCMTGAAFGAMNGLRLGLKETQSMAWSKPRNVQILNMVTRQGALWANTLGSLALLYSAFGVIIEKTRGAEDDLNTVAAGTMTGMLYKCTGG------LRGIARGGLAGLTLTSLYALYNNWVHMKGSLLQQSL---------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O14925-1", "uniprot_id": "TIM23_HUMAN", "id": "O14925-1", "name": "Mitochondrial import inner membrane translocase subunit Tim23", "aln": "---MEGGGGSGNKTTGGLAGFFGAGGAGYSHADLAGVP------LTG-------MNPLSPYLNVDP--RYLVQDTDEFILPTGAN---KTRGRFELAFFTIGGCCMTGAAFGAMNGLRLGLKETQNMAWSKPRNVQILNMVTRQGALWANTLGSLALLYSAFGVIIEKTRGAEDDLNTVAAGTMTGMLYKCTGG------LRGIARGGLTGLTLTSLYALYNNWEHMKGSLLQQSL---------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q5SRD1-1", "uniprot_id": "TI23B_HUMAN", "id": "Q5SRD1-1", "name": "Mitochondrial import inner membrane translocase subunit Tim23B", "aln": "---MEGGGGSGDKTTGVLAGFFGAGEAGYSHADLAGVP------LTG-------MNPLCPYLNVDP--RYLVQDTDEFILPTGAN---KTWGRFELAFFTIGGCCMTGAAFGAMNGLRLGLKETQNMAWSKPGNVQILNMVTRQGALWANTLGSLALLYSAFGVIIEKTRGAEDDLNTVAAGTMTGMLYKCT----------------VSEMALDSPFCVL-----LSGS---------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q7T2P6-1", "uniprot_id": "TIM23_DANRE", "id": "Q7T2P6-1", "name": "Mitochondrial import inner membrane translocase subunit Tim23", "aln": "---MDNSTPPPGGFKGGLGSIFGGGTPEYSNTELSGVP------LTG-------MSPLSPYLNVDP--RYLIQDTDEFILPTGAN---KTRGRFELAFFTIGGCCITGAAFGTLNGLRMGLSETRDMPWSKPRNVQILNMVTRQGASWANTLGSVALLYSVFGVAIEKARGAEDDLNTVAAGTLTGMVFKSTGG------LKGVARGGLIGLAMSGLYALYNNWDHLKGKSPSHY----------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0AC58H3S6-1", "uniprot_id": "A0AC58H3S6_DANRE", "id": "A0AC58H3S6-1", "name": "", "aln": "---MDKDS-SGSRNPAGFG-LFGSAGPQYSKAELAGVP------LTG-------MSPISPYLNVDP--RYLIQDTDEFILPTGAN---KTRGRFELAFFTIGGCCITGALCGAVNGLRMGLSETRNMAWSKPQNVQILNMVTRQGATWANTLGSVALLYSAFGVIIEKARGAEDDLNTIAAGTMTGVLYKSPAEDFIEQCFSTTFNQGFSSTFHPALHVFHVSFTKHTQIISSAAETERFVKGVTDKGDIQSMQCWWALRNVVEKHCHR", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P32897-1", "uniprot_id": "TIM23_YEAST", "id": "P32897-1", "name": "Mitochondrial import inner membrane translocase subunit TIM23", "aln": "MSWLFGDKTPTDDANAAVGGQDTTKPKELSLKQSLGFEPNINNIISGPGGMHVDTARLHPLAGLDKGVEYLDLEEEQLSSLEGSQGLIPSRGWTDDLCYGTGAVYLLGLGIGGFSGMMQGLQNIPPNSPGKLQLNTVLNHITKRGPFLGNNAGILALSYNIINSTIDALRGKHDTAGSIGAGALTGALFKSSKG------------LKPMGYSSAMVAAACAVWCSVKKRLLEK-----------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . . . . .. * : *. ::* : * .:* .** : ::: *:: : * : : *. : * * ..*: **.: . .* :** :*::*. .*. * :** *. :. *: ** .* .::.**::** ::*.. . ", "identical_positions": 34, "similar_positions": 57, "identity": "12.64%" }, { "cls_id": "homologset.agr.MGI:1858330", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q99JX7-1", "uniprot_id": "NXF1_MOUSE", "id": "Q99JX7-1", "name": "Nuclear RNA export factor 1", "aln": "--------------------MADEG------------KSYNEHDD-RVSFP-----QRRKKGRGPFR---------------WKCGEGNRRSGRGGSGVQSSRFEEDDGDVAMND-PQDGPRVRYNPYTNRPNRRGD--------GWHDRDRIHITVRRDRAPAERGGAGTSQDGTTKNWFKITIPYGRKYDKTWLLSMIQSKCS-VPFNPIEFHYENTRAHFFVEDATTASALKGVNHKIQDRENRRISIIINASAPPYTVQNELKPEQIEQLKLIMSKRYDGNQQALDLKGLRSDPDLVAQNIDVVLNRRSCMAATLRIIEENIP--ELLSLNLSSNRLYKLDDMSSIVQKAPNLKTLNLSGNELKTERELDKIKG--LKLEELWLDRNPMCDNFGDQSSYISAIRERFPKLLRLDGHELPPPISFDVEA-PTMLPPCKGSYFGTENLKSLVLRFLQQYYVIYDSGDRQGLLYAYHDGACCSLSIP------YNPQNPVRKNLAEYVKDSRNVKKLKEPTQRFRLLKHTRLNVVAFLNELPKTQHDVNAFVVDISAQTSTL-----LCFSVNGVFKEVDGKSRD----------------------------SLRAFTRTFIAVPASNSGLCIVNDELFVRNASPEEIQRAFAMSAPTPS-------------------------------SSPVPTLS---------------------------------PEQQEMLQAFSTQSGMNLEWSQKCLQDNNWDYTRSAQAFTLLKAKGEIPEVAFMK-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O88984-1", "uniprot_id": "NXF1_RAT", "id": "O88984-1", "name": "Nuclear RNA export factor 1", "aln": "--------------------MADEG------------KSYNEHDD-RVSFP-----QRRKKGRGPFR---------------WKCGVGNRRSGRGGSGIRSSRFEEDDGDVAMND-PQDGPRVRFNPYTTRPNRRRD--------TWHDRDRIHVTVRRDRAPQERGGAGTSQDGTTKNWFKITIPYGKKYDKMWLLSMIQSKCS-VPFNPIEFHYENTRAHFFVENATTASALKAVNYKIQDRENGRISIIINSSAPPYIVQNELKPEQVEQLKLIMSKRYDGSQQALDLKGLRSDPDLVAQNIDVVLNRRGCMAAALRIIEENIP--ELLSLNLSNNRLYKLDDMSSIVQKAPNLKILNLSGNELKSEWELDKIKG--LKLEELWLDRNPMCDTFLDQSTYISTIRERFPKLLRLDGHELPPPIAFDVEA-PTMLPPCKGSYFGTENLKSLVLHFLQQYYAIYDSGDRQGLLDAYHDGACCSLSTP------SNPQNPVRHNLAKYFNDSRNVKKIKDTTTRFRLLKHTRLNVVAFLNELPKTHHDVNSFVVDISAQTSTL-----LCFSVNGVFKEVDGKSRD----------------------------SLRAFTRTFIAVPASNSGLCIVNDELFVRNASPEEIQRAFAMPAPTPS-------------------------------SSPVPTLS---------------------------------QEQQDMLQAFSTQSGMNLEWSQKCLQDNNWDYTRSAQAFTHLKAKGEIPEVAFMK-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9UBU9-1", "uniprot_id": "NXF1_HUMAN", "id": "Q9UBU9-1", "name": "Nuclear RNA export factor 1", "aln": "--------------------MADEG------------KSYSEHDDERVNFP-----QRKKKGRGPFR---------------WKYGEGNRRSGRGGSGIRSSRLEEDDGDVAMSD-AQDGPRVRYNPYTTRPNRRGD--------TWHDRDRIHVTVRRDRAPPERGGAGTSQDGTSKNWFKITIPYGRKYDKAWLLSMIQSKCS-VPFTPIEFHYENTRAQFFVEDASTASALKAVNYKILDRENRRISIIINSSAPPHTILNELKPEQVEQLKLIMSKRYDGSQQALDLKGLRSDPDLVAQNIDVVLNRRSCMAATLRIIEENIP--ELLSLNLSNNRLYRLDDMSSIVQKAPNLKILNLSGNELKSERELDKIKG--LKLEELWLDGNSLCDTFRDQSTYISAIRERFPKLLRLDGHELPPPIAFDVEA-PTTLPPCKGSYFGTENLKSLVLHFLQQYYAIYDSGDRQGLLDAYHDGACCSLSIP------FIPQNPARSSLAEYFKDSRNVKKLKDPTLRFRLLKHTRLNVVAFLNELPKTQHDVNSFVVDISAQTSTL-----LCFSVNGVFKEVDGKSRD----------------------------SLRAFTRTFIAVPASNSGLCIVNDELFVRNASSEEIQRAFAMPAPTPS-------------------------------SSPVPTLS---------------------------------PEQQEMLQAFSTQSGMNLEWSQKCLQDNNWDYTRSAQAFTHLKAKGEIPEVAFMK-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0ACD6B623-1", "uniprot_id": "A0ACD6B623_DANRE", "id": "A0ACD6B623-1", "name": "Nuclear RNA export factor 1", "aln": "------------------MATADDS------------RYYNEHDD-RVGGPK----HRNRKGRGPFRAPLYSDQMSRPRHRGGHSGGGGGGGGGGGPGPRS-RLHDDDGDVTMSDIPQDSSQRRYNPYGRQQNRRDDRNRKGGRGGGGNDDRGGNRFGGRGGGGGGGGGGGLSDGRSKNWFKMTIPYGKKYDKDWLLSSLQSVCP-IPFHAVQYHLDGNRAQFYVEDSTTANAIFKVSRRITDKDGYKVAVIMNSCPPPTLIHSDLKPADLEHLKQCMAKRFDGSQQALDLNNIRVDPDLVSQNIEVTLNRKNSMCAVIKIIEENIP--ELVCLNLSNNRLFRLDDLVDIIHKVPNLKILNLSHNELKTERELDKLKG--LKLVDLSLEGNPLCHHFKIHADYISAIRERFPKLLKLDGHDLPPPIGFDLDDGPSTLPPSKASYFCSEEIKNIILCFLQQFYNIYDSGNRQPLLDAYHDGATFSLSIP------FVSLNPSKSTLGEYQKDSRNIKRMKDPTTRYRLIKHTRLNVVAFLNELPKTQHDIASFVVDVNTYTATL-----LAFTVCGVFKEMDGKSRE----------------------------TYRAFSRVFIAVPAGSTGLCIVNDELFVRNATTEEIRRAFVAPAPTPS-------------------------------SSPVPTLS---------------------------------AHQQEMLAAFSLKSGMNLEWSQKCLQDNDWDFERAAQIFTGLKAQGKIPDVAFVK-", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0AC58H6Y3-1", "uniprot_id": "A0AC58H6Y3_DANRE", "id": "A0AC58H6Y3-1", "name": "", "aln": "MSRYREWYPNLSVITRVCSSSSDSSGSTVVREVWHADRSFTGQDGHLVGVRQSWGSVKANLHNGPAR---------------LLHGSGAR--GRCGSGPRG-RMQNSSMDVSLMNGQFGTAKQRFIPYR-RPSWRGEGQVEMIGEGNKQRFRVGDEKKGGKQWFKMTLCFLQLLDASRVPLKQPIPHGKKYDKRWLLTSLQNLCP-IAFTPLHYTTEGDKVHFYLEDTTTASALSKLSRRILDSDGQRVVVLMNSCYFPPFLKSELRLEDLELLKLCLSKRFDDSQKSLDLTSIRTDPELVSHNVDIILNRKNCMQAVIKIIQESIP--ELLSLNLSKNKLYKLDGLTELVNKAPNLQSLNLSCNELKSHCELDKVKG--FRLVELCLDGNPLCDRFKDQTTYISAVQKCFPRLLRLDGHVLSLPICFEVET-SSNIPLCKGSHFVSNEIQGLIQRFLEQYYSIYDSGDRQPLLEAYHESACFSLCLP------SIS-NPSRYKL-DYFKNSRNVKNIKDSPTRFRLLKHTRLTVVACLNELPKTQHDINSINVDVNAYASTL-----LAFTVSGVFKEVDDQSED----------------------------LFKAFSRVFVTVPAQNSGLCIVNDELFVRNTTMEEIQCAFTTPTQSPS-------------------------------SSPVPILS---------------------------------AYQQEMLSAFSQMSEMNLQWSQKCLEDNAWDFQQAAQIFAELQAHGMIPEAAFIK-", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9U1H9-1", "uniprot_id": "NXF1_DROME", "id": "Q9U1H9-1", "name": "Nuclear RNA export factor 1", "aln": "--------------------MPKRG------------GGSSQRYN-------------NNVGNGGGR----------------YNAPEDFDDFDVEDRQRRKDRNKRRVSFKPSQCLHNKKDIKLRPEDLRRWDEDDD------MSDMTTAVKDRPTSRRRGSPIPRGKFGKLMPNSFGWYQVTLQNAQIYEKETLLSALLAAMSPHVFIPQYWRVERNCVIFFTDDYEAAERIQHLGKNGHLPDGYRLMPRVRSGIPLVAIDDAFK----EKMKVTMAKRYNIQTKALDLSRFHADPDLK--QVFCPLFRQNVMGAAIDIMCDNIP--DLEALNLNDNSISSMEAFKGVEKRLPNLKILYLGDNKIPSLAHLVVLRN--LSILELVLKNNPCRSRYKDSQQFISEVRRKFPKLVKLDGETLEPQITFDLSE-QGRLLETKASYLCDVAGAEVVRQFLDQYFRIFDSGNRQALLDAYHEKAMLSISMP------SASQAGRLNSFWKFNRNLR--RLLNGEENRTRNLKYGRLACVSTLDEWPKTQHDRRTFTVDLTIYNTSM-----MVFTVTGLFKELNDETNNP---------------------ASMELYDVRHFARTYVVVPQ-NNGFCIRNETIFITNATHEQVREFKRSQHQPAPGAMPSTSSAVTSPQAGAAAGLQGRLNALGVATGPVAILSGDPLAATAPVNSG----SAAISTTAVAPGAQDESTKMQMIEAMSAQSQMNVIWSRKCLEETNWDFNHAAFVFEKLFKENKIPPEAFMK-", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q99257-1", "uniprot_id": "MEX67_YEAST", "id": "Q99257-1", "name": "mRNA export factor MEX67", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------MSGFHNVGNINMMAQQQMQQNRIKISVRNWQNATMNDLINFISRNAR---VAVYDAHVEGPLVIGYVNSKAEAESLMKWNGVRFAGSNLKFELLDNNGASAGTSD------TISFLRGVLLKRYDPQTKLLNLGALHSDPELIQKGVFSSISTQSKMFPAMMKLASTEKSLIVESVNLADNQLKDISAISTLAQTFPNLKNLCLANNQIFRFRSLEVWKNKFKDLRELLMTNNPITT----DKLYRTEMLRLFPKLVVLDNVIVRDEQKLQTVY--SLPMKIQQFFFENDALGQSSTDFATNFLNLWDN-NREQLLNLYSPQSQFSVSVDSTIPPSTVTDSDQTPAFGYYMSSSRNISKVSSEKSIQQRLSIGQESINSIFKTLPKTKHHLQEQPNEYSMETISYPQINGFVITLHGFFEETGKPELESNKKTGKNNYQKNRRYNHGYNSTSNNKLSKKSFDRTWVIVPM-NNSVIIASDLLTVRAYSTGAWKTASIAIAQPPQQQASVLPQVASMNPN--------------ITTPPQPQPSVVPGGMSIPGAPQGAMVMAPTLQLPPDVQSRLNPVQLELLNKLHLETKLNAEYTFMLAEQSNWNYEVAIKGFQSSMNG--IPREAFVQF", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : .: : *:. : . : . : :. *. : . .. :. . . :: : **:: . : *:* :: **:* : : :. * ..: : .. : .:** .* : :. : : : ***: * *. *:: * :. : :* : *. : : : . **:*: **. : :: : .: * :: ::*. :*: ** * : *:. . : : . * :. : :. : : :. ***:*. : . : : ::: *.*:* . : : * *.:: ** .... * .: : : : : .. : * . * : ::: : : :* :: ::. *:: : * ** **:: ", "identical_positions": 56, "similar_positions": 147, "identity": "7.09%" }, { "cls_id": "homologset.agr.MGI:1858382", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A0G2K7H8-1", "uniprot_id": "A0A0G2K7H8_RAT", "id": "A0A0G2K7H8-1", "name": "", "aln": "MHPGFQQGHCQGHSHCGPPPAHGPGHCPGGNHPPGPGGPSHSHSPGHC-PGGNHPPGPGGPSHGHGPGHCPGGQHHPPGPGGPPHGHGSGHCGSHPGPHH", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8K0G7-1", "uniprot_id": "PHGR1_MOUSE", "id": "Q8K0G7-1", "name": "Proline, histidine and glycine-rich protein 1", "aln": "MHPG-------GKGHCGPPPGHGPGHCHEGHHPPGPGGPHPGHGPGHC-PGGHHPPGHGGPSHGHGPGHCPGG-HHPPGHGGPSHGHGPGHCGPHPGPHH", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "C9JFL3-1", "uniprot_id": "PHGR1_HUMAN", "id": "C9JFL3-1", "name": "Proline, histidine and glycine-rich protein 1", "aln": "MDPGPK-----GHCHCG---GHG--------HPPGHCGPPPGHGPGPCGPPPHHGPGPCGPPPGHGPGPCGPPPHHGPGPCGPPPGHGPGH--PPPGPHH", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*.** *: *** .** **** ** .*.** * * :* ** **. ***** * ** ** **. ***.** . *****", "identical_positions": 47, "similar_positions": 10, "identity": "47.0%" }, { "cls_id": "homologset.agr.MGI:1858414", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q5BKC9-1", "uniprot_id": "NGEF_RAT", "id": "Q5BKC9-1", "name": "Ephexin-1", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------METKNSEDQGKPQRKSVSSLWKSKHGPAEMRPELPP------ETAKETQNEEPRCLIPIQRNSLFN----------------------------RAMR--HKHKARSMSERRANDQAGDLPETRKSVNEPLAFN-LPQG----RLPPWRTPAQRGP-GAQEASESSS-----------------------------------------------------TPGNGTTPEECPALTDSPTTLTEALQMIHPIPADS--WRNLIEQIGLLYQEYRDKSTLQEIETRRQQDAEIQ---------------------------------------------------------GNSDGSQAGEDNAEEEEEEEE-------------------------------------------EPASPPERRALPQICLLSNPHSRFNLWQDLPEIQSSGVLDILQPEETKLQEAMFELVTSEASYYKSLNLLVSHFMENERLKK--ILHPSEAHILFSNVLDVMAVSERFLLELEHRMEENIVISDVCDIVYRYAADHFSVYITYVSNQTYQERTYKQLLQEK--TAFRELIAQLELDPKCKGLPLSSFLILPFQRITRLKLLVQNILKRVE-EGSEREGTALDAHKELEMVVKACNEGVRKMSRTEQMISIQKKMEFKIKS----------VPIISHSRWLLKQGELQQMS--GPKTSRTLRTKKLFREIYLFLFNDLLVICRQIP-GDKYQVFDSAPRGLLRVEELEDQ---------GQTLANVFILRLLENADDREATYMLKASSQSEMKRWMTSLAPNRRTKFVSFTSRLLDCPQVQCVHPYVAQQPDELTLELADILNILEKTEDGWIFGERLHDQERGWFPSSMTEEILNPKIRSQNLKECFRVHKMED-PQRSQNKDRRKLGSRNRQ--------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8CHT1-1", "uniprot_id": "NGEF_MOUSE", "id": "Q8CHT1-1", "name": "Ephexin-1", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------METKNSEDWGKPQRKSESSSRKSNHGPAEMRPALPPENREAPETGEETQNEEPRRLIPIQRHSLFN----------------------------RAVR--HRHKARSTSERRASDQA-DLPKMGKSVNERSAFN-LPQG----RLSPWRTPAQRDT-GAQEASESSS-----------------------------------------------------TPGNGTTPEECPALTDSPTTLTEALQMIHPIPADS--WRNLIEQIGLLYQEYRDKSTLQEIETRRQQDAEIQ---------------------------------------------------------GNSDGSQVGEDAGEEEEEEEEG---------------------------------------EEEELASPPERRALPQICLLSNPHSRFNLWQDLPEIQSSGVLDILQPEEIRLQEAMFELVTSEASYYKSLNLLVSHFMENERLKK--ILHPSEAHILFSNVLDVMAVSERFLLELEHRMEENIVISDVCDIVYRYAADHFSVYITYVSNQTYQERTYKQLLQEK--AAFRELIAQLELDPKCKGLPFSSFLILPFQRITRLKLLVQNILKRVE-ERSEREGTALDAHKELEMVVKACNEGVRKMSRTEQMISIQKKMEFKIKS----------VPIISHSRWLLKQGELQQMS--GPKTSRTLRTKKLFREIYLFLFNDLLVICRQIP-GDKYQVFDSAPRGLLRVEELEDQ---------GQTLANVFILRLLENADDREATYMLKASSQSEMKRWMTSLAPNRRTKFVSFTSRLLDCPQVQCVHPYVAQQPDELTLELADILNILEKTEDGWIFGERLHDQERGWFPSSMTEEILNPKIRSQNLKECFRVHKMED-PQRSQNKDRRKLGSRNRQ--------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8N5V2-1", "uniprot_id": "NGEF_HUMAN", "id": "Q8N5V2-1", "name": "Ephexin-1", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------METRESEDLEKTRRKSASDQWNTDNEPAKVKPELLPEKEETSQADQDIQDKEPHCHIPIKRNSIFN----------------------------RSIRRKSKAKARDNPERNASCLA-DSQDNGKSVNEPLTLN-IPWS----RMPPCRTAMQTDP-GAQEMSESSS-----------------------------------------------------TPGNGATPEEWPALADSPTTLTEALRMIHPIPADS--WRNLIEQIGLLYQEYRDKSTLQEIETRRQQDAEIE---------------------------------------------------------DNTNGSPASEDTPEEEEEEEE-----------------------------------------EEEPASPPERKTLPQICLLSNPHSRFNLWQDLPEIRSSGVLEILQPEEIKLQEAMFELVTSEASYYKSLNLLVSHFMENERIRK--ILHPSEAHILFSNVLDVLAVSERFLLELEHRMEENIVISDVCDIVYRYAADHFSVYITYVSNQTYQERTYKQLLQEK--AAFRELIAQLELDPKCRGLPFSSFLILPFQRITRLKLLVQNILKRVE-ERSERECTALDAHKELEMVVKACNEGVRKMSRTEQMISIQKKMEFKIKS----------VPIISHSRWLLKQGELQQMS--GPKTSRTLRTKKLFHEIYLFLFNDLLVICRQIP-GDKYQVFDSAPRGLLRVEELEDQ---------GQTLANVFILRLLENADDREATYMLKASSQSEMKRWMTSLAPNRRTKFVSFTSRLLDCPQVQCVHPYVAQQPDELTLELADILNILDKTDDGWIFGERLHDQERGWFPSSMTEEILNPKIRSQNLKECFRVHKMDD-PQRSQNKDRRKLGSRNRQ--------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "E7FDB4-1", "uniprot_id": "E7FDB4_DANRE", "id": "E7FDB4-1", "name": "", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MMAMTALFRGKWGHNNKPQEVQTK--PRTPVPQLPS---------EDDENEDETLRAPIRRNSRFY----------------------------RSMRKKKSAGPSEQQESPSSSPKPTVDPASYNRLSPAAANRVPLSPRLQKSPPSRSGISLLSNGVQGGVRSRSP--------------------------------------------------LASPGDWPRRLEMEELSERTTSACTMQDNDNHSTADPDNITFRLVRNGDSPQKMAVENSCHNLNIMKNVDVLYQ---------------------------------------------------------EYRDTSKQQEIDQRRQRDGLP-------------------------------------------TAGSGVLAAPALQLQLRSSTNS-LNLWQNLDAVKKSGLLQTLEPKEIILQEAMFELVTSEASYYKSLELLETHFLRNPLLVN--TLSQSDMHFLFSNITDIMKASEKFLMDLEHRIEESILISDVCDIVHFHAVNHFQVFISYVINQVYQETNYRRILQEN--CAFRENMAILENQPKVKGLSFTSFLILPFQRITRLKLLVQNILKRVE-ENSEKERTAILAHQELEKIVKQCNEGARKMSRTEELISIEKTLEFKSKS----------VPVISHSRWLLKKGEVQQMS--GPKSTRTMRSRKLYHPIYLFLFNNLLLITKRNSSGDKFQVLDSCSRSMLRTEDLEDQ---------GQMLACVFVLKLLENQEDREVSYMLKTESVSDKLRWICALTPNRRTRFLSTSTHEPDSPQVQCIQSYSSQEPDELSVEMADVLHILECTDDGWILGERLHDGERGWFPNRVVERIMSAEVRAQNLKECQRIQQAQEGAQGTRAASRGRVAVRNSQYNASWTDL", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VVC6-1", "uniprot_id": "Q9VVC6_DROME", "id": "Q9VVC6-1", "name": "", "aln": "MAMSPVLDAAAKAAGRDLNGNSNAASATAASTATPTAAAAAAATTPRKTKKTIINWLVNSDSENNNRATCDKAGKDNPNPNQNPNSQANPNQNCSCESRAFRDFRGVQTLRLLWSRRIKSASEDQCHSPVHCHTSSSSLGTLKKLNKSVSCLVNAFNNSRDCATPEKTLAKRAASLHNLQDSQAKHKQLHREKDNFYKYKNAEQAKMQAKLRSSADEAILNASETRAKRDDSGCLPGVKSYNSKALSAADKVAKVAKGEAKTQRRAEEPVGEAEVEVEVEFRAKREHNRLEGLSLSAASAQSGGSSESLQTTTTSSSTPTTHSSVTSSTGRSGGRRKYSFKTHAGKSYHQHHHPSRRTSNMDSSNGGISMVAKLTHQFNEIIQKDAKLLEQVKRNNGVWISRGTHVYKIVEKPTSEGKGLPNADDNRISTVQRNIKKFERLEKPSVPLKSEQLMRKHLELMRGSSLSRGPRIKRNLKLPPGSVGIPELAIVSEELKTPTSEEQAKKPKSVQNESQPNHPEELNQSNDKPSDELDLIMGEEGDEEELRQKQRKHKYASIYEKLRFTFAKGRKSASPSPTKAQIREEVSIDEESIKDSTSEDMVTRKEDFTLDLPKEVIPRAEDLEDSSHALLVSPCFEADAKILDALEAVDLKLKVLNPLNDVTTADGERELLLAANDDFEQRILPNSSFVYQAANKQYSNNQILLNQAVNVTLVNAIEGEQMIMEQKQLMKVRDLELTERDIDQPLKRAEKSPEKDDTLEPESLYEPITPVMDETKTEAQTSSLFKIYTKKSELVEDIYQTVEEASTVEVKPNNWLEGYESIAGSQEACPLTYDGYESFAPEEVVTTPTTPSATGTLGRNTRDELPELPKPKRVLNKSPIPLRPAPPKPQAKESEEDENIYDTIKGCYESMHCKATSSSSSGEATLTTDTISLSSNCYESISHIRRSRVATTQNQGHGSAGSCIQLSSSGSTLTISSDHKTNSLYESSLAAAGCVVYGSASVGCRSSLGSSAGSRDSGKPGDKRSSIAGSSDNSDAWVDISDGEIGQATTDATANEAQFIVVRERFKPHRTRSPDWSKRIRDKRLQQKKAISCIEDDSDHYYETLSPLGNKRHSTQLVRQSQDGNRSGGVRSSHRRSKNHSASAHTLGEHVVISDDYDSFETDSDDHGDGEPDLRQRNYNDSGVDMRNHRLPKPPPPQNQVYEFVRKFKDFISSKKSPKGSQQKLYENTPASTLFYVECSKRTEDVYENTDFGPERIPAPETKGPVHQEQAPVLRAKQKNGKSLRSRLRKSLVGSSFDTKQLSSLAPTRSTFYVEDPEGSLPALPLEPEIHGSGELDSGFSDKNCTPLPETPKFSTVARKAKKEAKANRRRTTIGLRPNDPPPPPPPMTGNKSPLDPERELDAEQTTSWYAECGVFKQATNGAVSPRGDEPVTPTPSGHGGVSSWYAESGLYQTSGISVASSSGSSGVSTGNEAGLGDELSSEPHSLFSNEPLYQMYSAAKLESITRDLEAHGSSDGYEEIGLQAKAKPEPLVKPRPTALQLVEPKNGPSRTLWSEIPEVIHSCILPTLTSRERSLQEAKFEIITSEASYLKSLNLLRRHFMNHNAFLDSSVLSAKDRKALFSYIVPVHECSERLLTELEACWQDNIMLLGLSRCIYEIAERHFHVYVAFCEHQGRMDRTLRRLKESKESLAFQQHLERLEASPSCCGLNLHSFLMLPMQRITRLPLLIDAVFSKESPLNREEYESWKLTLALVQKVVGQCNEAANRWEQAFELERIARQLEFPSHVRALAIAPVGVPRAGAKPRFLVKRGELTHLLWRGEDAKLTFGKRLTKISIYAFLFSDLLLLCKRRG-ESCFSVFDYCPRSMLTLAAGDSLPQLPTKDLKDQAGKNLILMTLLENCDRKTVELVLSCPSVSDQQRWLQAMRPPEAETPGEKLYESWDCPQVVAKHSYESDEPDVLQLELGDVVNVSRKLPDGWYQGERIRDGAVGWFPGSYTEELNSAHVRARNLKQRHRLLTFTATYLESQKSK------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : .. .:. . . : :..: * *: : : . . : . . . : . . : . .. . .. : *.: .. : *: : . .. :: :: *. . * * : . . . : .. . .**.:: : * :* * ..* **** **::****** ***:** **:.: : . * .: : *** : : **::* :** ::.*:: .:. :: * ** *:::: :* : . ::: :.: **:: : ** .*. ** : ***:**:****** **:: ::.: . *. : : :: :* ***...: .:: :: * : :** : ::.*:*:*:**: :: * .:. *: .: ** ***.:**:: :: . :.*:* ..*.:* :. .* :::: **** : : . :*. * *: **: :: * . . . *.*** . :.* :::** * :*:.*:::: *** ***::* ****. .*.: ...:*::***: *: :: . ", "identical_positions": 131, "similar_positions": 216, "identity": "6.4%" }, { "cls_id": "homologset.agr.MGI:1858415", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "F1MAM8-1", "uniprot_id": "F1MAM8_RAT", "id": "F1MAM8-1", "name": "Probable ATP-dependent RNA helicase DDX20", "aln": "-MAAAFEALPASTTSESAMAAELEAAPVPAAEPTPASPWNLRTAHDIGGPRTRTGDVVLAEPADFESLLLSRPVLEGLRAAGFERPSPVQLKAIPLGRCGLDLIVQAKSGTGKTCVFSTIALDSLILENYSTQILILAPTREIAVQIHSVITAIGIKMEGLECHVFIGGTPLSQDKTRLKKCHIAVGSPGRIKQLIELDYLNPGSIRLFILDEADKLLEE---GSFQEQINWIYSSLPASKQMLAVSATYPEILANALTRYMRDPTFVRLNPSDPSLIGLKQYYQVVNSYPLAHKIFEEKTQHLQELFSKIPFNQALVFSNLHSRAQHLADILSSKGFPTECISGNMNQNQRLDAMAKLKQFHCRVLISTDLTSRGIDAEKVNLVVNLDVPLDWETYMHRIGRAGRFGTLGLTVTYCCRGEEENMMMKIAQKCN--INLLPLP-DPIP------------------AGLMEECLDCDVEVKAAMHTYSSPSISTQSPKKQVQKPERAFQSQRTPGSHMPSPRNTSVSTLSAKSKHG-KQKLPVKSHSECGILEKAAPPQELGCTTHPEEQVKNSVQTSTEESSSNSLHQ---------------------------------------AKETSPGSLPKIPCLSSFKVHQL----------------------------------SALTFAELVEDYEHYIKE-----------------GLEKPVEIIRHYTGPGAQTVNPQNGFVRNRVSADRVQMLVSSSQSGDSESESDSCSSRTS---------------------------------------------------------------------------------------------SQSKGNKSYLEGSSDTQLKDSECTSVGGPLSLEQIQNG-------NDTSTQVEYQESPETQVKARHKEGANQ----------RSKPSRRNPPRRSSYRVQTE-AQEEGWHDCHRETNASSSDPYQDYEEYWRAYYRAWQEYYAAASHSYYWN--------------AQRHPSWMAAYHMNTVYLQEMMRGNQ----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9JJY4-1", "uniprot_id": "DDX20_MOUSE", "id": "Q9JJY4-1", "name": "Probable ATP-dependent RNA helicase DDX20", "aln": "MAAAAFEVPAALTTSESTMAAERAAAPVQAVEPTPASPWTQRTAHDIGGPRTRTGDVVLAEPADFESLLLSRPVLEGLRAAGFERPSPVQLKAIPLGRCGLDLIVQAKSGTGKTCVFSTIALDSLILENYSTQILILAPTREIAVQIHSVITAIGIKMEGLECHVFIGGTPLSQDKTRLKKCHIAVGSPGRIKQLIELDYLNPGSIRLFILDEADKLLEE---GSFQEQINWIYSSLPASKQMLAVSATYPEVLANALTRYMRDPTFVRLNPSDPSLIGLKQYYQVVNSYPLAHKIFEEKTQHLQELFSKVPFNQALVFSNLHSRAQHLADILSSKGFPTECISGNMNQNQRLDAMAKLKQFHCRVLISTDLTSRGIDAEKVNLVVNLDVPLDWETYMHRIGRAGRFGTLGLTVTYCCRGEEENMMMKIAQKCN--INLLPLP-DPIP------------------PGLMEECLNWDVEVKAAMHTYSSPTVATQSPKKQVQKLERAFQSQRTPGNQTPSPRNTSASALSARPKHS-KPKLPVKSHSECGVLEKAAPPQESGCPAQLEEQVKNSVQTSVEDSSSNSQHQ---------------------------------------AKDSSPGSLPKIPCLSSFKVHQP----------------------------------STLTFAELVDDYEHYIKE-----------------GLEKPVEIIRHYTGPEAQTGNPQNGFVRNRVSEDRAQMLVSSSQSGDSESDSDSCSSRTS---------------------------------------------------------------------------------------------SQSKGNKSYLEGSSDTQLKDTECTPVGGPLSLEQVQNG-------NDTPTQVEYQEAPETQVKARHKEGANQ----------RSKQSRRNPARRSSYRVQSE-PQEESWYDCHRETTASFSDTYQDYEEYWRAYYRAWQEYYAAASHSYYWN--------------AQRHPSWMAAYHMNTVYLQEMMRGNQ----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9UHI6-1", "uniprot_id": "DDX20_HUMAN", "id": "Q9UHI6-1", "name": "Probable ATP-dependent RNA helicase DDX20", "aln": "-MAAAFEASGALAAVATAMPAEHVAVQVPAPEPTPGPVRILRTAQDLSSPRTRTGDVLLAEPADFESLLLSRPVLEGLRAAGFERPSPVQLKAIPLGRCGLDLIVQAKSGTGKTCVFSTIALDSLVLENLSTQILILAPTREIAVQIHSVITAIGIKMEGLECHVFIGGTPLSQDKTRLKKCHIAVGSPGRIKQLIELDYLNPGSIRLFILDEADKLLEE---GSFQEQINWIYSSLPASKQMLAVSATYPEFLANALTKYMRDPTFVRLNSSDPSLIGLKQYYKVVNSYPLAHKVFEEKTQHLQELFSRIPFNQALVFSNLHSRAQHLADILSSKGFPAECISGNMNQNQRLDAMAKLKHFHCRVLISTDLTSRGIDAEKVNLVVNLDVPLDWETYMHRIGRAGRFGTLGLTVTYCCRGEEENMMMRIAQKCN--INLLPLP-DPIP------------------SGLMEECVDWDVEVKAAVHTYGIASVPNQPLKKQIQKIERTLQIQKAHGDHMASSRNNSVSGLSVKSKNNTKQKLPVKSHSECGIIEKATSPKELGCDRQSEEQMKNSVQTPVEN-STNSQHQ---------------------------------------VKEALPVSLPQIPCLSSFKIHQP----------------------------------YTLTFAELVEDYEHYIKE-----------------GLEKPVEIIRHYTGPGDQTVNPQNGFVRNKVIEQRVPVLASSSQSGDSESDSDSYSSRTS---------------------------------------------------------------------------------------------SQSKGNKSYLEGSSDNQLKDSESTPVDDRISLEQPPNG-------SDTPNPEKYQESPGIQMKTRLKEGASQ----------RAKQSRRNLPRRSSFRLQTE-AQEDDWYDCHREIRLSFSDTYQDYEEYWRAYYRAWQEYYAAASHSYYWN--------------AQRHPSWMAAYHMNTIYLQEMMHSNQ----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9PQW1-1", "uniprot_id": "A0A8M9PQW1_DANRE", "id": "A0A8M9PQW1-1", "name": "Probable ATP-dependent RNA helicase DDX20", "aln": "--MCAQEGAVIHSSCHLFTVEETERCRDRNMAAS------VKAAHELQS-RTRTDDVLISGGVEFSSLLLSKPVLEGLSASGFQRPSPIQLKAIPLGRCGLDLIVQAKSGTGKTCVFTTIALDSLILENATTQVLVLAPTREIAVQIHAVVMAIGSAMEGLECHVFIGGRPISQDKQHLKKCHIAIGSPGRIKQLIEMGALMVSSIRLFVLDEADKLLEDDSSSSFQEQINWIYSSLPANKQMLALSATYPESLAQQLSRYMREPTFVRLNPTDPGLLGLKQYYKIVPSHSLPHKVFEEKVQSLLELFSKIPFNQALVFSNLHTRAQHLADILSSKGLPAVCISGGLSQDQRLEAMWKLKQYQCRVLISTDLTSRGIDAEKVNLVINLDVPQDWETYMHRIGRAGRFGTLGVAVTYCCHGEEENKMMAIAQKCS--LDLMHLP-DPIP------------------PGIMEEACDHDVII----ETLSKPKIPDN-FKPEKKKKAKSEQMKSKP------SRESHISVVITESVTG------DKSCSRAETKTKNHSSK-------PGRQKQMAPAANLQHDSTITQKQ---------------------------------------QND----TLPKIPPLSSFKSHTG----------------------------------KRITFDDALVDYETFIRE-----------------GPGRSVEIIHQYDGFYRSQDKVNGLHDAHDEDEASESYVLEESQSHQDLPPAQEVSELSS---------------------------------------------------------------------------------------------EQKTSSESSSE--SEMEVESESSSSVPSKSTLEALPDNKVSLVRNHSELAELALPSTRVPQQATRSKKRPCQP---------QSQDTAHHHNLPHKHRTASK-SSRRPTGPKRRTRETDETEEEEAGQDYWSS-YRAWAEYYN----SYYHH--------------SPYN--WMTAFYMNSVYIKEMMKH------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9V3C4-1", "uniprot_id": "DDX20_DROME", "id": "Q9V3C4-1", "name": "DEAD-box RNA helicase gemin3", "aln": "--------------------------------------MEREIAHSLAGGEERSSDVAPGQVKTFEELRLYRNLLNGLKRNNFVTPTKIQAAAIPMALAKMDLIIQSKSGTGKTLIYVIAVVQSFNPNINQPHAMIVVPTRELAIQVQDTFFHLCKSFRDFKCSAFIGGTDVAKDRKRMNESRVIIGTPGRLLHLYENRVFDVSKLRLLVLDEADQLYQT---KSLQHTVSKLIEAMPKNRQIIACSATYDQNLDERLAKVMDKPMLISNSERATVLLGIRQFVYELPQQNNSVEEMRLKLQILGQIFNQLPYEQAIIFASSQMRADSYKNYLTASGIDCHLISGAMEQSERLHVFEGYRNFTMRILVATDLMARGVDSPHANLVINIDPPQDHVTYLHRIGRAGRFGSKGIAITFIASKKESQRFREMSKKIATAWSVLEFPKEPMPNEFNFWDFEKYNFDYYIKEENPLQEMPMPIKENRSKENVDASSVDLENLQKDQDGKRRDPDKLPVALENVETQKELELENLPESSHNNKNLRVKEKEIVRQGKLKETNSKAGGSKTNKTERRKKSNTPSKLQKQITEVQQTPEITVNKYYMQEDIQRTADGKEYHPVNGAGNHQVPSKSNQKPVEFISPELTPTLTPLELTQEPSPTTVTPPAPPANSINNKTYCLAAPTQTSSMTIQNMVISNTVDDASSISSDSMVVCGYHSDRSYDTYYATSDEEEIWNRLMSKQRRQLKSKRGHGKRRVILYKKVFPKLKANVKRKLKKRMSSSCRSKKAHHLRKRHVYKNISLLPHMNLCHLLQKFTNQERFLKRLHKYAKNQFIDNARVGFLLDKLYKSILEMYYNSAKERKKHFKEAMKESLKSIDNYESQESSESEEEEEEEKDLKNKLSVHVTNQMDIPPMPQAAVEIGSGSESDTEDSQEYGEGEEIIVDDEDDGSDGGPNSSSGFVESQESVSSGIDTSVYETESTGASGNNSSAFFISDDESDTESLTDSEAGSNVSATGSSSQRSSVASSTYESSDDDSVTVTNVSSMQNAQSLWLQTFNMQYQFIASHVAKNLQNYY", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . *:.: . . *:.** . *..* * : :*:** .* *: :* ***:. . :***:*:******* :: .::*: : .: :::.****:*:*:: .. : :..::* .**** :::*: ::::.:: :*:***: :* * : ..:**::*****:* : *:*. :. : .::* .:*::* **** : * : *:: * .* :: . . *:*::*: : . . : :. * * * ::*.::*::**::*:. : **: : *::.*: *** :.*.:**..: ::: *:*::*** :**:*: :.***:*:* * * **:**********: *:::*: . :*.: : :::* .:: :* :*:* : : .. . ..: : : : . : : :: . : . . *. . : . .: : : :. : : : : * *:.:: :.: : : * . : . ** .: . : : . . .:: . . * :. ... ..:* * .: :::. . * . : : . : . :. : .:: : .. : .. . :: : . . * * : *: :: *: :: . : ", "identical_positions": 136, "similar_positions": 267, "identity": "12.72%" }, { "cls_id": "homologset.agr.MGI:1858416", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O88506-1", "uniprot_id": "STK39_RAT", "id": "O88506-1", "name": "STE20/SPS1-related proline-alanine-rich protein kinase", "aln": "--------------------------------------------------------------------------------------------MAEPSGSPVHVQLPQQAAPVTAAAA-APAAATSAP-----------------APAPAPA--APAAPAPAPAAAPAPAPAAQAVG---------WPICRDAYELQEVIGSGATAVVQAALCKPRQERVAIKRINLEKCQTSMDELLKEIQAMSQCSHPNVVTYYTSFVVKDELWLVMKLLSGGSMLDIIKYIVNRGEHKNGVLEEAIIATILKEVLEGLDYLHRNGQIHRDLKAGNILLGEDGSVQIADFGVSAFLATGGDVTRNKVRKTFVGTPCWMAPEVMEQVRGYDFKADMWSFGITAIELATGAAPYHKYPPMKVLMLTLQNDPPTLETGVEDKEMMKKYGKSFRKLLSLCLQKDPSKRPTAAELLKCKFFQKAKNREYLIEKLLTRTPDIAQRAKKVR-RVPGSSGHLHKTEDGDWEWSDDEMDEK-SEEGK--------AAASQEKSRRVKE-ENPEISVNAGGIPEQIQSLSVHDSQGQP--------------------NANEDYREGP-CAVNLVLRLRNSRKELNDIRFEFTPGRDTADGVSQELFSAGLVDGHDVVIVAANLQKIVDDPKALKTLTFKLASGCDGAEIPDEVKLIGFAQLSVS-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9Z1W9-1", "uniprot_id": "STK39_MOUSE", "id": "Q9Z1W9-1", "name": "STE20/SPS1-related proline-alanine-rich protein kinase", "aln": "--------------------------------------------------------------------------------------------MAEPSGSPVHVQLSQQAAPVTAAAATAPAAATSAP-----------------APAPAPAPAASAAPAPAPAAAPAPAPAAQAVG---------WPICRDAYELQEVIGSGATAVVQAALCKPRQERVAIKRINLEKCQTSMDELLKEIQAMSQCSHPNVVTYYTSFVVKDELWLVMKLLSGGSMLDIIKYIVNRGEHKNGVLEEAIIATILKEVLEGLDYLHRNGQIHRDLKAGNILLGEDGSVQIADFGVSAFLATGGDVTRNKVRKTFVGTPCWMAPEVMEQVRGYDFKADMWSFGITAIELATGAAPYHKYPPMKVLMLTLQNDPPTLETGVEDKEMMKKYGKSFRKLLSLCLQKDPSKRPTAAELLKCKFFQKAKNREYLIEKLLTRTPDIAQRAKKVR-RVPGSSGHLHKTEDGDWEWSDDEMDEK-SEEGK--------AAASQEKSRRVKE-ENSEISVNAGGIPEQIQSLSVHDSQAQP--------------------NANEDYREGP-CAVNLVLRLRNSRKELNDIRFEFTPGRDTADGVSQELFSAGLVDGHDVVIVAANLQKIVDDPKALKTLTFKLASGCDGSEIPDEVKLIGFAQLSVS-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9UEW8-1", "uniprot_id": "STK39_HUMAN", "id": "Q9UEW8-1", "name": "STE20/SPS1-related proline-alanine-rich protein kinase", "aln": "--------------------------------------------------------------------------------------------MAEPSGSPVHVQLPQQAAPVTAAAAAAPAAATAAP-----------------APA------APAAPAPAP------APAAQAVG---------WPICRDAYELQEVIGSGATAVVQAALCKPRQERVAIKRINLEKCQTSMDELLKEIQAMSQCSHPNVVTYYTSFVVKDELWLVMKLLSGGSMLDIIKYIVNRGEHKNGVLEEAIIATILKEVLEGLDYLHRNGQIHRDLKAGNILLGEDGSVQIADFGVSAFLATGGDVTRNKVRKTFVGTPCWMAPEVMEQVRGYDFKADMWSFGITAIELATGAAPYHKYPPMKVLMLTLQNDPPTLETGVEDKEMMKKYGKSFRKLLSLCLQKDPSKRPTAAELLKCKFFQKAKNREYLIEKLLTRTPDIAQRAKKVR-RVPGSSGHLHKTEDGDWEWSDDEMDEK-SEEGK--------AAFSQEKSRRVKE-ENPEIAVSASTIPEQIQSLSVHDSQGPP--------------------NANEDYREASSCAVNLVLRLRNSRKELNDIRFEFTPGRDTADGVSQELFSAGLVDGHDVVIVAANLQKIVDDPKALKTLTFKLASGCDGSEIPDEVKLIGFAQLSVS-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1RIB3-1", "uniprot_id": "A0A8M1RIB3_DANRE", "id": "A0A8M1RIB3-1", "name": "non-specific serine/threonine protein kinase", "aln": "--------------------------------------------------------------------------------------------MSMHELSPSCSRIRDVSLRMCSSQAVVNVIQQRSD-----------------PHG------RPMAEHSDSPAALQSPQPAPTTG---------WPIVKEAYELQEVIGSGATAVVQAALCSPRQERVAIKRINLEKCQTSMDELLKEIQAMSQCSHPNVVTYYTSFVVKDELWLVMKLLSGGSVLDIIKHTFNKGEHRNGVLDESTIASILKEVLEGLDYLHKNGQIHRDVKAGNILLGEDGSVQIADFGVSAFLATGGDVTRHKVRKTFVGTPCWMAPEVMEQVRGYDFKADIWSFGITAIELATGSAPYHRYPPMKVLMLTLQNDPPSLETGVEDKEMLKKYGKSFRKLISLCLQKDPAKRPTAAELLKCKFFQKAKNREYLMEKLLTKGPNISQRAKKVR-RVPGSSGHLHKTEDGDWEWSDDEMDER-SEEGK--------AAVNHERSRRVKENENQHGEVNANSLP--LEDLSIQHPQVQP--------------------LEKPSSAHGA---VNMVLRLRNSKKELNDIRFEFTPGQDTADGVSQELFSAGLVNGHDVVVVAANLQKIVEDPVTYKVLTFKLASGCDSTEIPDEVKLIGFAQLSVT-", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A126GUV7-1", "uniprot_id": "A0A126GUV7_DROME", "id": "A0A126GUV7-1", "name": "non-specific serine/threonine protein kinase", "aln": "MQLLNLVCLKQKVAHIANNNNNQNQSKESQERDPKDTGIFGCFAKKEEQQHNPKKKQSEGPRESSNSGSYKVQQTEQEQRRESENEHPSVYRQQDEEFHPIKKEEPQKTPPISKQPRPRNTPRSQSQPAINNRRRPGTPPPHTVAPGNGTASSRSMTSIPANLSSNNVAGAATLPGAAAPPEKYTWPNSKDDYELRDVIGVGATAVVHGAYCIPRNEKCAIKRINLEKWNTSMDELLKEIQAMSSCFHENVVTYHTSFVVREELWLVLRLLEGGSLLDIIKHKMRTSNCKQGVFDEATIATVLKEVLKGLEYFHSNGQIHRDIKAGNILIGDDGTIQIADFGVSAWLATGRDLSRQKVRHTFVGTPCWMAPEVMEQDHGYDFKADIWSFGITAIEMATGTAPYHKYPPMKVLMLTLQNDPPTLDTGADDKDQYKAYGKTFRKMIVECLQKEPSKRPTASELLKHAFFKKAKDRKYLTQTLLQSGPSMETRVHKAAKRQPGASGRLHRTVTGEWVWSSEEEDNGGSATGSGTGDRKHPSSDSDSEDRPMNRLERADSSDSDREEPSPEITHSVSSATVTPGAPAAAGAGAAQELTAGIAQLPLPSEAAGEAPPVNLVLRMRNLRRELHDIRFEFVVGKDTAEGIATELVDAGLVDALDTQPMATHLDQLIAASATMKTITFQLSSGVQPGEVPDERSLVGYAQISITD", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . * . : : : . : . . . : . . .* * ** :: ***::*** ******:.* * **:*: ********* :**************.* * *****:*****::*****::**.***:*****: .. .: ::**::*: **::*****:**:*:* *******:******:*:**::*********:**** *::*:***:**************** :*******:*********:***:****:****************:*:**.:**: * ***:***:: ****:*:*****:**** **:***:*:** :.** *.: *.:*. * **:**:**:* *:* **.:* *: * *. :: .....* ::. *. . . * *: . * . . **:***:** ::**:******. *:***:*:: **..****:. *. :*::*:::: . : *.:**:*:** : *:*** .*:*:**:*:: ", "identical_positions": 279, "similar_positions": 143, "identity": "39.46%" }, { "cls_id": "homologset.agr.MGI:1858417", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P61619-1", "uniprot_id": "S61A1_HUMAN", "id": "P61619-1", "name": "Protein transport protein Sec61 subunit alpha isoform 1", "aln": "-MAIKFLEVIKPFCVILPEIQKPERKIQFKEKVLWTAIT--LFIFLVCCQIPLFGIMSSDSADPFYWMRVILASNRGTLMELGISPIVTSGLIMQLLAGAKIIEVG-DTPKDRALFNGAQKLFGMIITIGQSIVYVMTGMYGDPSEMGAGICLLITIQLFVAGLIVLLLDELLQKGYGLGSGISLFIATNICETIVWKAFSPTTVNTGRG--MEFEGAIIALFHLLATRTDKVR-ALREAFYRQNLPNLMNLIATIFVFAVVIYFQGFRVDLPIKSARYRGQYNTYPIKLFYTSNIPIILQSALVSNLYVISQMLSARFSGNLLVSLLG-TWSDTSSGGPARAYPVGGLCYYLSPPESFGSVLEDPVHAVVYIVFMLGSCAFFSKTWIEVSGSSAKDVAKQLKEQQMVMRGHRETSMVHELNRYIPTAAAFGGLCIGALSVLADFLGAIGSGTGILLAVTIIYQYFEIFVKE---------QSEVGSMGALLF", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P61621-1", "uniprot_id": "S61A1_RAT", "id": "P61621-1", "name": "Protein transport protein Sec61 subunit alpha isoform 1", "aln": "-MAIKFLEVIKPFCVILPEIQKPERKIQFKEKVLWTAIT--LFIFLVCCQIPLFGIMSSDSADPFYWMRVILASNRGTLMELGISPIVTSGLIMQLLAGAKIIEVG-DTPKDRALFNGAQKLFGMIITIGQSIVYVMTGMYGDPSEMGAGICLLITIQLFVAGLIVLLLDELLQKGYGLGSGISLFIATNICETIVWKAFSPTTVNTGRG--MEFEGAIIALFHLLATRTDKVR-ALREAFYRQNLPNLMNLIATIFVFAVVIYFQGFRVDLPIKSARYRGQYNTYPIKLFYTSNIPIILQSALVSNLYVISQMLSARFSGNLLVSLLG-TWSDTSSGGPARAYPVGGLCYYLSPPESFGSVLEDPVHAVVYIVFMLGSCAFFSKTWIEVSGSSAKDVAKQLKEQQMVMRGHRETSMVHELNRYIPTAAAFGGLCIGALSVLADFLGAIGSGTGILLAVTIIYQYFEIFVKE---------QSEVGSMGALLF", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P61620-1", "uniprot_id": "S61A1_MOUSE", "id": "P61620-1", "name": "Protein transport protein Sec61 subunit alpha isoform 1", "aln": "-MAIKFLEVIKPFCVILPEIQKPERKIQFKEKVLWTAIT--LFIFLVCCQIPLFGIMSSDSADPFYWMRVILASNRGTLMELGISPIVTSGLIMQLLAGAKIIEVG-DTPKDRALFNGAQKLFGMIITIGQSIVYVMTGMYGDPSEMGAGICLLITIQLFVAGLIVLLLDELLQKGYGLGSGISLFIATNICETIVWKAFSPTTVNTGRG--MEFEGAIIALFHLLATRTDKVR-ALREAFYRQNLPNLMNLIATIFVFAVVIYFQGFRVDLPIKSARYRGQYNTYPIKLFYTSNIPIILQSALVSNLYVISQMLSARFSGNLLVSLLG-TWSDTSSGGPARAYPVGGLCYYLSPPESFGSVLEDPVHAVVYIVFMLGSCAFFSKTWIEVSGSSAKDVAKQLKEQQMVMRGHRETSMVHELNRYIPTAAAFGGLCIGALSVLADFLGAIGSGTGILLAVTIIYQYFEIFVKE---------QSEVGSMGALLF", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q90YL4-1", "uniprot_id": "S61A2_DANRE", "id": "Q90YL4-1", "name": "Protein transport protein Sec61 subunit alpha-like 2", "aln": "-MAIKFLEVIKPFCAVLPEIQKPERRIQFKEKVLWTAIT--LFIFLVCCQIPLFGIMSSDSADPFYWMRVIMASNRGTLMELGISPIVTSGLIMQLLAGAKIIEVG-DTPKDRALFNGAQKLFGMIITIGQAVVYVMTGMYGDPSEMGAGICLLIIIQLFVAGLIVLLLDELLQKGYGLGSGISLFIATNICETIVWKAFSPTTVNTGRG--TEFEGAIIALFHLLATRTDKVR-ALREAFYRQNLPNLMNLIATIFVFAVVIYFQGFRVDLPIKSARYRGQYNTYPIKLFYTSNIPIILQSALVSNLYVISQMLSTRFSGNFLVNLLG-TWSDTSTGGPARAYPVGGLCYYLSPPESFGTVLEDPIHAIIYIIFMLGSCAFFSKTWIEVSGSSAKDVAKQLKEQQMVMRGHRETSMVHELNRYIPTAAAFGGLCIGGLSVMADFLGAIGSGTGILLAVTIIYQYFEIFVKE---------QSEVGSVGALLF", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q90ZM2-1", "uniprot_id": "S61A1_DANRE", "id": "Q90ZM2-1", "name": "Protein transport protein Sec61 subunit alpha-like 1", "aln": "-MAIKFLEVIKPFCAVLPEIQKPERKIQFREKVLWTAIT--LFIFLVCCQIPLFGIMSSDSADPFYWMRVILASNRGTLMELGISPIVTSGLIMQLLAGAKIIEVG-DTPKDRALFNGAQKLFGMIITIGQAIVYVMTGMYGDPSEMGAGICLLIIIQLFVAGLIVLLLDELLQKGYGLGSGISLFIATNICETIVWKAFSPTTVNTGRG--TEFEGAIIALFHLLATRTDKVR-ALREAFYRQNLPNLMNLIATVFVFAVVIYFQGFRVDLPIKSARYRGQYNTYPIKLFYTSNIPIILQSALVSNLYVISQMLSTRFSGNFLVNLLG-TWSDTSSGGPARAYPVGGLCYYLSPPESFGSVLDDPVHAVIYIVFMLGSCAFFSKTWIEVSGSSAKDVAKQLKEQQMVMRGHRETSMVHELNRYIPTAAAFGGLCIGGLSVMADFLGAIGSGTGILLAVTIIYQYFEIFVKE---------QSEVGSMGALLF", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P32915-1", "uniprot_id": "SC61A_YEAST", "id": "P32915-1", "name": "Protein transport protein SEC61", "aln": "MSSNRVLDLFKPFESFLPEVIAPERKVPYNQKLIWTGVS--LLIFLILGQIPLYGIVSSETSDPLYWLRAMLASNRGTLLELGVSPIITSSMIFQFLQGTQLLQIRPESKQDRELFQIAQKVCAIILILGQALVVVMTGNYGAPSDLGLPICLLLIFQLMFASLIVMLLDELLSKGYGLGSGISLFTATNIAEQIFWRAFAPTTVNSGRG--KEFEGAVIAFFHLLAVRKDKKR-ALVEAFYRTNLPNMFQVLMTVAIFLFVLYLQGFRYELPIRSTKVRGQIGIYPIKLFYTSNTPIMLQSALTSNIFLISQILFQKYPTNPLIRLIG-VWG-IRPGTQGPQMALSGLAYYIQPLMSLSEALLDPIKTIVYITFVLGSCAVFSKTWIEISGTSPRDIAKQFKDQGMVINGKRETSIYRELKKIIPTAAAFGGATIGALSVGSDLLGTLGSGASILMATTTIYGYYEAAAKEGGFT-----KNLVPGFSDLM-", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P38353-1", "uniprot_id": "SSH1_YEAST", "id": "P38353-1", "name": "Sec sixty-one protein homolog", "aln": "MSGFRLIDIVKPILPILPEVELPFEKLPFDDKIVYTIFAGLIYLFAQFPLVGLPKATTPNVNDPIYFLRGVFGCEPRTLLEFGLFPNISSGLILQLLAGLKVIKVNFKIQSDRELFQSLTKVFAIVQYVILTNIFIFAGYFG--DDLSVVQIGLINFQLVGAGIFTTLLAEVIDKGFGFSSGAMIINTVVIATNLVADTFGVSQIKVGEDDQTEAQGALINLIQGLRSKHKTFIGGIISAFNRDYLPNLTTTIIVLAIAIIVCYLQSVRVELPIRSTRARGTNNVYPIKLLYTGCLSVLFSYTILFYIHIFAFVLIQLVAKNEPTHIICKIMGHYENANNLLAVPTFPLSLLAPPTSFFKGVTQQPLTFITYSAFILVTGIWFADKWQAISGSSARDVALEFKDQGITLMGRREQNVAKELNKVIPIAAVTGASVLSLITVIGESLGLKGKAAGIVVGIAGGFSLLEVITIEYQQSGGQSALNQVLGVPGAM-", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . :.:::.**: .***: * .:: : :*:::* .: : :* : * :.: **:*::* ::..: **:*:*: * ::*.:*:*:* * ::::: . .** **: *: .:: : : : :::* :* .::. *: :**. *.::. ** *::.**:*:.** :: :. *. :. :*. : :: *.. * :**:* ::: * : .. .: .** * ***: : .: : .* *:*..* :***:*:: ** . *****:**. .:::. :: :.::: :* . * :: . . . *. * : . :*: : * *:* : *:..* :**:*.:*:* ::*:* :.: *:** .: :**:: ** **. *. :. ::* .: ** *..:.*::. : : * . * . * .. : ", "identical_positions": 109, "similar_positions": 189, "identity": "22.11%" }, { "cls_id": "homologset.agr.MGI:1858418", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9WTJ5-1", "uniprot_id": "RAMP1_MOUSE", "id": "Q9WTJ5-1", "name": "Receptor activity-modifying protein 1", "aln": "MAPGLRGLPRCGLWLLLAHHLFMVTACRDPDYGTLIQELCLSRFKENMETIGKTLWCDWGKTIQSYGELTYCTKHVAHTIGCFWPNPEVDRFFIAVHHRYFSKCPISGRALRDPPNSILCPFIALPITVTLLMTALVVWRSKRTEGIV-------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0ABK0LH29-1", "uniprot_id": "A0ABK0LH29_RAT", "id": "A0ABK0LH29-1", "name": "Receptor activity-modifying protein 1", "aln": "MAPGLRGLPRRGLWLLLAHHLFMVTACRDPDYGTLIQELCLSRFKEDMETIGKTLWCDWGKTIGSYGELTHCTKLVANKIGCFWPNPEVDKFFIAVHHRYFSKCPVSGRALRDPPNSILCPFIVLPITVTLLMTALVVWRSKRTEGIVNFHLKMSAWWRSEEVTVSPVTGVMVIVSHHDSLQHGLWNLGRAQHRARSSQVAPHQQDHHD", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O60894-1", "uniprot_id": "RAMP1_HUMAN", "id": "O60894-1", "name": "Receptor activity-modifying protein 1", "aln": "MARALCRLPRRGLWLLLAHHLFMTTACQEANYGALLRELCLTQFQVDMEAVGETLWCDWGRTIRSYRELADCTWHMAEKLGCFWPNAEVDRFFLAVHGRYFRSCPISGRAVRDPPGSILYPFIVVPITVTLLVTALVVWQSKRTEGIV-------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "** .* *** ************.***::.:**:*::****::*: :**::*:*******:** ** **: ** :*..:******.***:**:*** *** .**:****:****.*** ***.:*******:******:******** ", "identical_positions": 102, "similar_positions": 33, "identity": "48.8%" }, { "cls_id": "homologset.agr.MGI:1858419", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q80WL2-1", "uniprot_id": "BYST_RAT", "id": "Q80WL2-1", "name": "Bystin", "aln": "MPKLKVTRGARNQERHAPLAEQILAGD-AVRAGTREKRRRHGV------EEEEEYVGPRLSRRILQQARQQQEELETEHATGDRPAKPRERATRLGPGVPQDGSDEEDEEWPTLEKAAKMTVVNHQAE---VVVDPEDERAIEMFMNKNP---PVRRT--LADIIMEKLTEKQTEVETVMSEV--------------SGFPMPQ---LDPRVLEVYRGVREVLCKYRSGILPKAFKIIPALSNWEQILYVTEPEAWTAAAMYQATRIFASNLKERMAQRFYNLVLLPRVRD--DIAEYKRLNFHLYMALKKALFKPGAWFKGILIPLCESGTCTLREAIIVGSIISKCSIPVLHSSAAMLKIAEMEYSGASSIFLRLLLDKKYALPYRVLDALVFHFLAFR---------TEKRQLPVLWHQCLLTLAQRYKADLATEQKEALLELLRLQPHPQLSPEIRRELQSAVPRDVE-----------------DVVVTME-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O54825-1", "uniprot_id": "BYST_MOUSE", "id": "O54825-1", "name": "Bystin", "aln": "MPKFKVTRGASNREKHAPLAEQILAGN-AVRAGTREKRRGREV------EEEEEYVGPRLSRRILQQARQQQEELETDHGAGDRSAPPRERATRLGPGLPQDGSDEEDEEWPTLEKAAKMAGVDHQAE---VIVDPEDERAIEMFMNKNP---PVRRT--LADIIMEKLTEKQTEVETVMSEV--------------SGFPMPQ---LDPRVLEVYRGVREVLCKYRSGKLPKAFKVIPALSNWEQILYVTEPEAWTAAAMYQATRIFASNLKERMAQRFYNLVLLPRVRD--DIAEYKRLNFHLYMALKKALFKPGAWFKGILIPLCESGTCTLREAIIVGSIITKCSIPVLHSSAAMLKIAEMEYSGANSIFLRLLLDKKYALPYRVLDALVFHFLAFR---------TEKRQLPVLWHQCLLTLAQRYKADLATEQKEALLELLRLQPHPQLSPEIRRELQSAVPRDVE-----------------DGGVTME-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q13895-1", "uniprot_id": "BYST_HUMAN", "id": "Q13895-1", "name": "Bystin", "aln": "MPKFKAARGVGGQEKHAPLADQILAGN-AVRAGVREKRRGRGTG-----EAEEEYVGPRLSRRILQQARQQQEELEAEHGTGDKPAAPRERTTRLGPRMPQDGSDDEDEEWPTLEKAATMTAAGHHAE---VVVDPEDERAIEMFMNKNP---PARRT--LADIIMEKLTEKQTEVETVMSEV--------------SGFPMPQ---LDPRVLEVYRGVREVLSKYRSGKLPKAFKIIPALSNWEQILYVTEPEAWTAAAMYQATRIFASNLKERMAQRFYNLVLLPRVRD--DVAEYKRLNFHLYMALKKALFKPGAWFKGILIPLCESGTCTLREAIIVGSIITKCSIPVLHSSAAMLKIAEMEYSGANSIFLRLLLDKKYALPYRVLDALVFHFLGFR---------TEKRELPVLWHQCLLTLVQRYKADLATDQKEALLELLRLQPHPQLSPEIRRELQSAVPRDVE-----------------DVPITVE-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P51406-1", "uniprot_id": "BYS_DROME", "id": "P51406-1", "name": "Bystin", "aln": "MGKPKKAN--VATIKNVNLEKQITEGR-VAKNKNKDKVK---LR-----AEESANIDARSSQKILAAAKLQQLELDEEN----FPSLVTVKKVNFS---LNDGHVKEDEE---------VNETDLMAD---LDMDEDDVAAFERFQQPAQ---EGKRTLHLSKMIMQKIQEKEADIHTKISDE--------------GSLKIEE---IDPKVKEMYEGVRDVLKRYRSGKIPKAFKIIPKLRNWEQILFITEPHNWSAAAMFQGTRIFCSVLSQAMAQRFYNLVLLPRVRD--DLCEYKKLNMHLYNALKRALFKPAAFMKGIILPLLEGGDCTLREAIIFGSVVARSSIPVLHSSACLLKICEMAYSGANSIFIRYFLDKRYALPYRVVDAAVFHFLRFE---------NDKRELPVLWHQSLLTFAQRYKNDISSEQRDALLQLLKKKSHFKITPDVRRELQAASCRDVEMMETDNGLAGQPAKMYTDADVEYEG", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P38333-1", "uniprot_id": "ENP1_YEAST", "id": "P38333-1", "name": "Essential nuclear protein 1", "aln": "MARASSTK--ARKQRHDPLLKDLDAAQGTLKKINKKKLAQNDAANHDAANEEDGYIDSKASRKILQLAKEQQDEIEGEELAESERNKQFEARFTTMSYDDEDEDEDEDEEAFGEDISDFEPEGDYKEEEEIVEIDEEDAAMFEQYFKKSDDFNSLSGSYNLADKIMASIREKESQVEDMQDDEPLANEQNTSRGNISSGLKSGEGVALPEKVIKAYTTVGSILKTWTHGKLPKLFKVIPSLRNWQDVIYVTNPEEWSPHVVYEATKLFVSNLTAKESQKFINLILLERFRDNIETSEDHSLNYHIYRAVKKSLYKPSAFFKGFLFPLVETG-CNVREATIAGSVLAKVSVPALHSSAALSYLLRLPFSPPTTVFIKILLDKKYALPYQTVDDCVYYFMRFRILDDGSNGEDATRVLPVIWHKAFLTFAQRYKNDITQDQRDFLLETVRQRGHKDIGPEIRRELLAGASREFVDPQEAN----------DDLMIDVN-", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* : . :. :: * .:: . . : :.* *. :..: *::** *: ** *:: :. :* .**** . : : :* :* :* : : : *:. ** .: **::::. .: ..: : : :* : * * .:* : * :** **:** * **::::::*:*. *:. .:::.*::* * *. :*:* **:** *.** : .* : ** *:* *:*::*:**.*::**:::** * * *.:*** * **:::: *:*.*****.: : .: :* ..::*:: :***:*****:.:* *::*: *. .* ***:**:.:**:.**** *:: :*:: **: :: : * .: *::**** :. *:. * : : ", "identical_positions": 123, "similar_positions": 151, "identity": "24.75%" }, { "cls_id": "homologset.agr.MGI:1858420", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q96EZ8-1", "uniprot_id": "MCRS1_HUMAN", "id": "Q96EZ8-1", "name": "Microspherule protein 1", "aln": "----------------------MDKDSQGLLDSSLMASGTASRSEDEESLAGQKRAS------SQALGTIP-----------------KRRSSSRFIKRKKFDDELVESSLAKSSTRAKGASGVEPGRCSGSE------------------PSSSEKKKVS-----------------KAPSTPVPPS-PAPAPGLTKRVKKSKQP-------------------------------LQVTKDLGRWKPADDLLLINAVLQTNDLTSVHLGVKFSCRFTLREVQERWYALLYDPVISKLACQAMRQLHPEAIAAIQSKALFSKAEEQLLSKVGSTSQPTLETFQDLLHRHPDAFYLARTAKALQAHWQLMKQYYLLEDQTVQPLPKGDQ-VLNFSDAEDLIDDSKLKDMRDEVLEHELMVADRRQKREIRQLEQELHKWQVLVDSITG-MSSPDFDNQTLAVLRGRMVRYLMRSREITLGRATKDNQIDVDLSLEGPAWKISRKQGVIKLKNNGDFFIANEGRRPIYIDGRPVLCGSKWRLSNNSVVEIASLRFVFLINQDLIALIRAEAAKITPQ--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q99L90-1", "uniprot_id": "MCRS1_MOUSE", "id": "Q99L90-1", "name": "Microspherule protein 1", "aln": "----------------------MDKDSQGLLDSSLMASGTASRSEDEESLAGQKRAS------SQALGTIP-----------------KRRSSSRFIKRKKFDDELVESSLAKSSTRVKGAGGVESGRCSGSE------------------PSSSEKKKVS-----------------KAPSTPVPPS-PAPTPGLTKRVKKSKQP-------------------------------LQVTKDLGRWKPADDLLLINAVLQTNDLTSVHLGVKFSCRFTLREVQERWYALLYDPVISKLACQAMRQLHPEAIAAIQSKALFSKAEEQLLSKVGSSSQPTLETFQDLLHTHPDAFYLARTAKALQAHWQLMKQYYLLEDQTVQPLPKGDQ-VLNFSDAEDLIDDSKLKDMRDEVLEHELTVADRRQKREIRQLEQELHKWQVLVDSITG-MGSPDFDNQTLAVLRGRMVRYLMRSREITLGRATKDNQIDVDLSLEGPAWKISRKQGVIKLKNNGDFFIANEGRRPIYIDGRPVLCGSKWRLSNNSVVEIASLRFVFLINQDLIALIRAEAAKITPQ--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8I6A524-1", "uniprot_id": "A0A8I6A524_RAT", "id": "A0A8I6A524-1", "name": "Microspherule protein 1", "aln": "----------------------LFLDSQGLLDSSLMASGTASRSEDEESLAGQKRAS------SQALGTIP-----------------KRRSSSRFIKRKKFDDELVESSLAKSSTRVKGAGSVESGRCSGSE------------------PSSSEKKKVS-----------------KAPSTPVPPS-PAPTPGLTKRVKKSKQP-------------------------------LQVTKDLGRWKPADDLLLINAVLQTNDLTSVHLGVKFSCRFTLREVQERWYALLYDPVISKLACQAMRQLHPEAIAAIQSKALFSKAEEQLLSKVGSTSQPTLETFQDLLHRHPDAFYLARTAKALQAHWQLMKQYYLLEDQTVQPLPKGDQ-VLNFSDAEDLIDDSKLNSLLPFHFTSELTVADRRQKREIRQLEQELHKWQVLVDSITG-MSSPDFDNQTLAVLRGRMVRYLMRSREITLGRATKDNQIDVDLSLEGPAWKISRKQGVIKLKNNGDFFIANEGRRPIYIDGRPVLCGSKWRLSNNSVVEIASLRFVFLINQDLIALIRAEAAKITPQ--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9VZJ3-1", "uniprot_id": "Q9VZJ3_DROME", "id": "Q9VZJ3-1", "name": "", "aln": "MEASRITAIASSAVSVTAPNPPTVSTIPTAAASTLIQVGVSPATTTMPTPAATTTTTTIGSTASSAVGISTPIRNPISNLQIEQQNDQKRRSSSRTIKRKRFDDEIVEYNIAVPTNRSGTDANRSSRPRTTSQNYPALVGVPHTTLAPLNIPTSTPQTPLSVDSLLPGTPSTVASLSLATPTTPAPLATPLPVAPIVTAVAHPKPPAMERSTTSERRSRPVRPASKKAQRRNGRPMGQMATKDLGRWKPIDDLALIIGIQQTNDLRIIHRGVKFSCKFTLQELQQRWYALLYEPAVSRIAVSAIRNLHPELVESVQRKALYSVQEEDLLGTIKSSEQPKLEQFQELLDKNASVFYCARTAKSLQNHWLLLKQYTLLPDQSVKPIYGTDQQPLSFSDAEDQIFEHDLNEPRDEALEMERALADRRNKRNIRLLENELSRWAVLVDSVLSPTAASEFDNQTLACLCGRHVRYLMRSKEITFGRDAKDCVVDVDLGLEGPAAKISRRQGTIKLRSNGDFFIANEGKRAIFIDGTPLLSANKARLGHNCTVEISGLRFTFLVNYELINAIRQESAKTSNPLN", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *:*: *.:. : : *. . :: *.*:* . ******* ****:****:** .:* .:.* .. .. : *: *:*: :. :* :*:**.* : * *.. :.. * :.* * .********* *** ** .: ***** :* ******:***:*:*:*******:*.:*::* .*:*:**** : ::* ***:* **:**..: *:.**.** **:**. :...** *****:** ** *:*** ** **:*:*: ** *.****** * : .*:. : * :****:**:** **:** :* *****: . .:.:******* * ** *******:***:** :** :****.***** ****:**.***:.**********:*.*:*** *:*...* **.:*..***:.***.**:* :** ** *:** : ", "identical_positions": 234, "similar_positions": 125, "identity": "40.48%" }, { "cls_id": "homologset.agr.MGI:1858421", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0ABK0L0N8-1", "uniprot_id": "A0ABK0L0N8_RAT", "id": "A0ABK0L0N8-1", "name": "", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------MFVSLPTFQAKSMARSLLEDQRTLACRYSGSPHAGMAEDNPDAKSPKTGAR-PQGGAEAG-----------------------------EPTTLLQRLRGTISKAVQNKVEGILQEVQKFSDNDKLYLYLQLPSGPSTGDKSSEP--SILSNEEYMYAYRWIRNHLEEHMDTCLPKQSVYDAYRKYCESLACCRPLSTANFGKIIREIFPDIKARRLGGRGQSKYCYSGIRRKTLVSMPPLPGLDLKGSESP----------EMGPEVSPAPRDELVEAACALTCDWAERILKRSFSSIVQVAR-------YLLQQHLISARSAHAHVLKAGGLAEEEERGPRERSSCKSKNG---VENLEGGGPK----------------KPERPAQPPKELEARAGTDSPGRSERKKSVIDSSVPAASKPQVNALVARLPVLLPR----------------------------------------------------------APRSLITPI------------SGTLKVATLPLPTRVGGPQAAVPIINMILPPVPTLS--GPGPGPGLGPRFGPG---------------------------------------------------------------------PGSGSGPGLGAGPGPGPGPGLGAGPGLGPGLGAGVGPGPGLGAGPGQRPGLRAGVGPGPGLGAGLGLGPGRVPPRAPILPRGTESREVGISGDP--------------------------------------------------------------RPHDKGVKRTAEVPLSEASGQDPP-----------------------------------------VKEMKHETEDT-VSEAKRKRGRPRKKTGGSGERNATPEKSAAAVNSPRSPRLLWET-----------------------------------------WGSKRENNLVGRPERPGAVGEAQRETVLAQGQEDGAVSKGE---------------------------------------KSLSSQEAKEAEDKIPPVTSKVSVIKG-RIQKEALQLVKG----------------------------EADAATQGNKGLKGRVLQSS------------------LTHEHKDPKATPP------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9JL61-1", "uniprot_id": "RFX5_MOUSE", "id": "Q9JL61-1", "name": "DNA-binding protein Rfx5", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MAEDKPDAKSPKTGAR-PQGGADAG-----------------------------EPTTLLQRLRGTISKAVQNKVEGILQEVQKFSDNDKLYLYLQLPSGPSVGEKSSEP--SLLSNEEYMYAYRWIRNHLEEHMDTCLPKQSVYDAYRKYCESLACCRPLSTANFGKIIREIFPDIKARRLGGRGQSKYCYSGIRRKTLVSMPPLPGLDLKGSESP----------EMGPEVSPAPRDELVEAACALTCDWAERILKRSFSSIVQVAR-------YLLQQHLISARSAHAHVLKAGGLAEEDERAPRERSLCKSKNV---VESLEGGGPK----------------KPERPAQPPKEQEARAGTDLPGRAERKKSVIDSSVPAASKPQVNALVARLPVLLPR----------------------------------------------------------APRSLITPI------------SGTLKVATLPLPTRVGGPQTAVPIINMILPPVPTLSGAGPGPGPGLGPRFGPG---------------------------------------------------------------------PG--------LGPGPGPGLGAGLGPGLGPGLGA--GPGPGLGAG----------------LGAGLGLGPGRVPPRAPILPRGAENREVGISSDP--------------------------------------------------------------RPHDKGIKRTAEVPLSEASGQDPP-----------------------------------------VKEMKHETQDTTVSEAKRKRGRPRKKPGGSGERNATPEKSAAIVNSPRSPRLLWET-----------------------------------------WGSKRENNFIGRPEGPGPGGEAERETVLVQGQQDGAVSKGE---------------------------------------RSLSSQEAKEAEDKIPPVTSKVSVIKG-RIQKEALQLVKG----------------------------EADAATQGNKGLKGRVLQSS------------------LTPEHKDPKATPP------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P48382-1", "uniprot_id": "RFX5_HUMAN", "id": "P48382-1", "name": "DNA-binding protein RFX5", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MAEDEPDAKSPKTGGRAPPGGAEAG-----------------------------EPTTLLQRLRGTISKAVQNKVEGILQDVQKFSDNDKLYLYLQLPSGPTTGDKSSEP--STLSNEEYMYAYRWIRNHLEEHTDTCLPKQSVYDAYRKYCESLACCRPLSTANFGKIIREIFPDIKARRLGGRGQSKYCYSGIRRKTLVSMPPLPGLDLKGSESP----------EMGPEVTPAPRDELVEAACALTCDWAERILKRSFSSIVEVAR-------FLLQQHLISARSAHAHVLKAMGLAEEDEHAPRERS-SKPKNG---LENPEGGAHK----------------KPERLAQPPKDLEARTGAGPLARGERKKSVVESSAPGANNLQVNALVARLPLLLPR----------------------------------------------------------APRSLIPPIPVSPPILAPRLSSGALKVATLPLSSRAGAPPAAVPIINMILPTVPALP-------------------------------------------------------------------------------------------------GPGPGPG----------------------------------------------------RAPPGGLTQPRGTENREVGIGGDQ--------------------------------------------------------------GPHDKGVKRTAEVPVSEASGQAPP-----------------------------------------AKAAKQDIEDT-ASDAKRKRGRPRKKSGGSGERNSTPLKSAAAMESAQSSRLPWET-----------------------------------------WGSGGEGNSAGGAERPGPMGEAEKGAVLAQGQGDGTVSKGG---------------------------------------RGPGSQHTKEAEDKIPLVPSKVSVIKGSRSQKEAFPLAKG----------------------------EVDTAPQGNKDLKEHVLQSS------------------LSQEHKDPKATPP------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A0B4KGM5-1", "uniprot_id": "A0A0B4KGM5_DROME", "id": "A0A0B4KGM5-1", "name": "RFX-type winged-helix domain-containing protein", "aln": "MSEKHGQLGAQWTKSAAPAATTAPVSNSIPIPQPIPVALPLQKPNANPYGNCSLQPADIVYSATRFQGPAIHAKGSPLTITPVGPVGGAPASAQISPTSHTHVPVPVATPSGFVPPPFSNATSASGGVSTSVLTPNPFATASANAAGLAFANAFSFSTAQQLGLGKIMHAMGGATAGVPSAPVPVTTTPATAAPSTPTIAGPRHPNEGVPAASGVINSTIAENVMNALSNSNSAGSVPSEEKMRRVLQVIETSLDDNAKLQISQILERVSGLKPIEKLFLYLRLPGECADTDPLRQPQNPLGTRSEINHTINWVRSHLEHDAQVSIPKQDVYNDYIAYCERLS-IKPLSTADFGKVMKQVFPGVRPRRLGTRGNSRYCYAAMRKTTKLTPPQLPQLCKTEQIVAGDSNSDPSQLTSASSLGGLPSTGGDSECWDVVRSWAEKLLNTKLESVADLSSRIKSNNATVSTKKYTPREPKEKRVLADIGPLKKRRKKKRKGSTSSESSCNQLVTGQDAGSSQEASDEQILKIKQEIIDSPIHPQQPPIGYLQQVTPMNLATDQRSSSAVRNLTPKILEMGSPAVVLTQQEVSPTGIVIKDEVEDYTSNIFCKKVLKAQQTKGFWANSPSSGTTSGVGLLVPPTITTTSATPPPPNSETSPVPGPGLSMGP--PSQMMSTSSVSPSSTVDTTPKVASRNQMMILRAKRLMAAENAALAAAEDSGLPENLGLPRERVISICNMDKHELDDYFLPGEDEENSEEPDNELLQYFQMGDAEEKQLNSLDAAEQNKNPQEPPTMGSAPEAMPAPGRGAAVVAAAAAMLAPVPAPSMLPAQAGVGSASASLALMSKKHQQQNQHQNLQLQRSKQLPLISNNKRKISLSNASSNGSNKNCIFLPISPNTNGSVTTPTATGSSNPSQNCFASPGLTRMKQRPNLLSKQQSLDCDNRDPMIGAHRKGRGYVYSYPTSTSASAPPSPSILPQWMCRNWSLGGGNISSFADSSHSADPLVNQNSMDLETSLALTGENELDTSEMQRSQSVPLSQLQRRGSQQSPSLNFYSENSNSQQSAPLKETGLLYEEVEVDSLLSANFTRKFNSITQQTATTCSSSAGSSSGYSSGGSAGIVSRSVPSTPLPHQQQNSLTSLNGGGGAASSGGGVMGIGNGGNCGVGNGFFTISDSFNWEGSTSNNSQLGYAHSYSARNSLDISKSMPTTPIATQRFRYSPAEVHRDFLINGNTIDSLPSSAFAGGVVPTDPTLALSTDTLIDDSAPSSADVVEAMIGVTGILDDFXNLHEEKAQGEIEISEQQEPDAVEENEVQSAAKEDANVVACLLQHVDQL", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . . :... :* * * *. *. : :** :. ::.. .: ::. **: *. :. :**:***:**. : : :* . :..* :: .*:*.***.. :..:***.**: * *** *: :*****:***:::::**.::.**** **:*:***:.:*:.* :: * ** * . . . ...: * . . :. .***::*: .:.*:.::: : :: . .. . :** * :: .: *: * .. .. : . :.*. : .* : *** :. . . :*..*.: . .* : *:* : * .*.* .*: * :..:::. .: .. . ... :*:: . * .** *.. : * * . :.. ... .* ** . . * * ::. *. .. :: .*: :*.:. * .: *.:::.. : : ...:.. ** :.* . . . . . . . :: :: . .*:.*.* :. .::.: : ...:* .. .. :: : . * :* * :. .. .: :: : *:::*.*. ", "identical_positions": 116, "similar_positions": 253, "identity": "8.71%" }, { "cls_id": "homologset.agr.MGI:1858422", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0ABK0LT65-1", "uniprot_id": "A0ABK0LT65_RAT", "id": "A0ABK0LT65-1", "name": "", "aln": "MGQCY---YNETIGFFYNNSGKELSLHWRPKDVVVVALGLTVSVLVLLTNLLVIAAIASNRRFHQPIYYLLGNLAAADLFAGMAYLFLMFHTGPRTARLSIKGWFLRQGLLDTSLTASVATLLAIAVERHRSVMAVQLHSRLPRGRVVTLIVGVWVAALGLGLLPAHFWHCLCDLDSCSRMVPLFSRSYLAVWALSSLLVFLLMVAVYTRIFFFVRRRVERMAEHVSCHPRYRETTLSLVKTVVIILGAFVVCWTPGQVVLLLDGLDCKSCNVLAVEKYFLLLAEANSLVNAVVYSCRDAEMRRTFRRLLCCTCLRWSHHKSAHYS-------------------------SSARTGASTRIMLPENGHPLMDSTL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9JL06-1", "uniprot_id": "LPAR2_MOUSE", "id": "Q9JL06-1", "name": "Lysophosphatidic acid receptor 2", "aln": "MGQCY---YNETIGFFYNNSGKELSLHWRPKDVVVVALGLTVSVLVLLTNLLVIAAIASNRRFHQPIYYLLGNLAAADLFAGMAYLFLMFHTGPRTARLSIKGWFLRQGLLDTSLTASVATLLAIAVERHRSVMAVQLHSRLPRGRVVTLIVGVWAAALGLGLLPAHFWHCLCDLDSCSRMVPLFSRSYLAAWALSSLLVFLLMVAVYTRIFFYVRRRVERMAEHVSCHPRYRETTLSLVKTVVIILGAFVVCWTPGQVVLLLDGLDCKSCNVLAVEKYFLLLAEANSLVNAVVYSCRDAEMRRTFRRLLCCMCLRWSSHKSARYS-------------------------ASAQTGASTRIMLPENGRPLMDSTL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9HBW0-1", "uniprot_id": "LPAR2_HUMAN", "id": "Q9HBW0-1", "name": "Lysophosphatidic acid receptor 2", "aln": "MGQCY---YNETIGFFYNNSGKELSSHWRPKDVVVVALGLTVSVLVLLTNLLVIAAIASNRRFHQPIYYLLGNLAAADLFAGVAYLFLMFHTGPRTARLSLEGWFLRQGLLDTSLTASVATLLAIAVERHRSVMAVQLHSRLPRGRVVMLIVGVWVAALGLGLLPAHSWHCLCALDRCSRMAPLLSRSYLAVWALSSLLVFLLMVAVYTRIFFYVRRRVQRMAEHVSCHPRYRETTLSLVKTVVIILGAFVVCWTPGQVVLLLDGLGCESCNVLAVEKYFLLLAEANSLVNAAVYSCRDAEMRRTFRRLLCCACLRQSTRESVHYT-------------------------SSAQGGASTRIMLPENGHPLMDSTL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F1QFF1-1", "uniprot_id": "F1QFF1_DANRE", "id": "F1QFF1-1", "name": "", "aln": "MVFNSCEAFDNPVSYFYNRTGKPISPNWRTHDFVVVGLGLPICVFIILANMLVIAAIIVNRKFHFPIYYLLGNMAAADLFAGISYSYLVFHTGPWTINLTIKEWFVRGALINMSLTASVVNLLAVAVERHQTIFTMQLHTTMTRRRVVMLIVTIWVVAVVMGLVPTMGWNCVCDQLGCSTVAPLYSRSFLVFWAILNLMAFFIMVAVYTHIFIYVRRRSQVMSPHTD-QPSNNQTVISLMKTMSMILGAFVICWTPGLVILLLDGLKCIECHVLKYEKYCLVLAECNSLVNPIIYSFRDEDMRTTYKRILCFPWRRMRPHEGPSGIRFEPVK-------------------TGAPPEKNSQNSSSPEAAPPQSPLS", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8M2BIF4-1", "uniprot_id": "A0A8M2BIF4_DANRE", "id": "A0A8M2BIF4-1", "name": "", "aln": "MVCYN----NETVVFFYSISHKNISDTWGTKAKAVVGMGLLVSVFVIFTNILVMAAIFMNRRFHYPIYYLLGNLAAADLFAGTSYMYLMFHTGPWTAKLTTYQWFVRQGLIDTSLTASVFNLMAIALERHQTIFTMQLHSKMTNHRVVLLILGIWTVAIIMGLVPAMGWNCMCDIGNCSTMAPLYSRSYLVFWAAINLLTFTVMVAVYTRIFIYVRRKSQRMSQHTS-QVKHKETVVNLMKTVVMILGCFVVCWTPGMVLLLLDGL-CHSCDVLTYEKFFLVLAESNSLMNPIIYSYRDKDMRDTFKRILCLCCRSKQSEE-HSGVRFNTLEQERRRRVQQESYLARRARDAGAQQENGGRLVLQENKEMLESSDS", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* ::.: :**. : * :* * .: .**.:** :.*:::::*:**:*** **:** ********:******** :* :*:***** * .*: **:* .*:: ****** .*:*:*:***::::::***: :.. *** **: :*..*: :**:*: *:*:* ** :.** ***:*. ** .*:.* :******:**::***: : *: *.. : .:*.:.*:**: :***.**:***** *:****** * .*.** **: *:***.***:*. :** ** :** *::*:** .: :.* . : : .. ", "identical_positions": 149, "similar_positions": 106, "identity": "39.63%" }, { "cls_id": "homologset.agr.MGI:1858429", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P49427-1", "uniprot_id": "UB2R1_HUMAN", "id": "P49427-1", "name": "Ubiquitin-conjugating enzyme E2 R1", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MARPLVPSS--QKALLLELKGLQE--EPVEGFRVTLVDEGDLYNWEVAIFGP-PNTYYEGGYFKARLKFPIDYPYSPPAFRFLTKMWHPNIYETGDVCISILHPPVDDPQSGELPSERWNPTQNVRTILLSVISLLNEPNTFSPANVDASVMYRKWKESKGKDREYTDIIRKQVLGTKVDAERDGVKVPTTLAEYCVK-TKAPAPDEG--SDLFYDDYYEDGEVE---EEADSCFGD--------DEDDSGTEES---------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "D4A453-1", "uniprot_id": "D4A453_RAT", "id": "D4A453-1", "name": "E2 ubiquitin-conjugating enzyme", "aln": "WETRADPAPLPHKPRPTPHPQPRPLDVTEKAPKAAAATPQRAAQPCPPLRTQASAELFRPEATAASGASETQGACAAGRGKKTTLPGVPRGRARRHIPDPVEASHRRILDPAVARRCISGPAAAARSRIRGPGVARRRIRGPKEARRRIRGREPVRRRIRGPAAAARRRVRRGPGRAEASAGRAAAPERVEPSGSPGGGGGGGAEEEGGGSPPAGARPGPSRELAPVPRPGPAPAPGPSAAAAVTAMARPLVPSS--QKALLLELKGLQE--EPVEGFRVTLVDEGDLYNWEVAIFGP-PNTYYEGGYFKARLKFPIDYPYSPPAFRFLTKMWHPNIYETGDVCISILHPPVDDPQSGELPSERWNPTQNVRTILLSVISLLNEPNTFSPANVDASVMYRKWKESKGKDREYTDIIRKQVLGTKVDAERDGVKVPTTLAEYCVK-TKAPAPDEG--SDLFYDDYYEDGEV----EEADSCFGD--------EEDDSGTEES---------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0A140T8I4-1", "uniprot_id": "A0A140T8I4_MOUSE", "id": "A0A140T8I4-1", "name": "E2 ubiquitin-conjugating enzyme", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MAGPLVPSS--QKVLLLELKGLQE--EPVEGFRVTLVDEGDLYNWEVAIFGP-PNTYYEGGYFKAHLKFPIDYPYSPPTFWFLTKMWHPNIHETGFVCISILHPPDDNPQGGELPSERWNPTQNVRTILLSVISLLNEPNTSSPANVDASVMYRKWKESKGKDHEYTDIIRKQVLGTKVDAERDGVKVPTTLAEYCVK-TKAPAPDEG--SDLF--DYYVDGEV----EEADSCFGD--------EEDDFGPKSPDPRP-----------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9VUR4-1", "uniprot_id": "Q9VUR4_DROME", "id": "Q9VUR4-1", "name": "UBC core domain-containing protein", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MTTAASTSQHATSSSTMMAGSG------------------------------------SLATSSSAAAPTTTPSSSAVRALAMEYKSLQE--EPVEGFRVKLINDDNLFEWEVAIFGP-PDTLYQGGYFKAHMKFPHDYPYSPPSIRFLTKVWHPNVYENGDLCISILHPPVDDPQSGELPCERWNPTQNVRTILLSVISLLNEPNTFSPANVDASVMYRRWRDSQGKDNEYPNIIRKQALAANAEAKREGIVVPMTLEDYCLKPTRKPTTESGLDANFYDDDFDLETEDD---LPSDDDFDE--------DDDDDEDEDEDEDSATAPISKNNGGSSKCKNNGLVREAAAAGADDAESADDSGKGETT---", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P14682-1", "uniprot_id": "UBC3_YEAST", "id": "P14682-1", "name": "Ubiquitin-conjugating enzyme E2-34 kDa", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSSRKSTASS----LLLRQYRELTDPKKAIPSFHIELEDDSNIFTWNIGVMVLNEDSIYHGGFFKAQMRFPEDFPFSPPQFRFTPAIYHPNVYRDGRLCISILHQS-GDPMTDEPDAETWSPVQTVESVLISIVSLLEDPNINSPANVDAAVDYRKNPE------QYKQRVKMEVERSKQDIP-KGFIMPTSESAYISQSKLDEPESNKDMADNFWYDSDLDDDENGSVILQDDDYDDGNNHIPFEDDDVYNYNDNDDDDERIEFEDDDDDDDDSIDNDSVMDRKQPHKAEDESEDVEDVERVSKKI", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : ..** * : : * : :.: .*:: * ::.::: *::.:: :: *.**:***:::** *:*:*** : * . ::***::. * :****** . .:* .* .* *.*.*.*.::*:*::***::** *******:* **: : :* : :: :. :: : .*. :* : * : . . .. :: : * : : *. :.: ::* :. ", "identical_positions": 62, "similar_positions": 90, "identity": "11.23%" }, { "cls_id": "homologset.agr.MGI:1858430", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P59222-1", "uniprot_id": "SREC2_MOUSE", "id": "P59222-1", "name": "Scavenger receptor class F member 2", "aln": "MEGAGSRGAGPARRQGARGLG--------LLLLLWLLPGLAAPQDLNPRGRNVCRTPGSQVLTCCAGWRQLGDECGIAVCEGNSTCSENEVCVRPGECRCRHGYFGANCDTKCPRQFWGPDCKERCSCHPHGQCEDVTGQCTCHARRWGARCEHACQCQHGTCHPRSGACRCEPGWWGAQCASACYCSATSRCDPQTGACLCHVGWWGRSCNNQCACNSSPCEQQSGRCQCRERMFGARCDRYCQCSHGRCHPVDGTCACDPGYRGKYCREPCPAGFYGPGCRRRCGQCKGQQPCTVVEGRCLTCEPGWNGTKCDQPCATGFYGEGCGHRCPPCRDGHACNHVTGKCTHCNAGWIGDRCETKCSNGTYGEDCAFVCSDCGSGHCDFQSGRCLCSPGVHGPHCNVTCPAGLHGVDCAQACSCHEESCDPVTGACHLETNQRKGVMGAGALLTLLLGLLLSLLGCCCACRGKDSARR-----ELTLGRKKAPQRFCGSFSRISMKLPRIPLRRQKLPKVVVAHHDLDNTLNCSFLDPPSGLEQPSPSWSSRASFSSFDTTDEGPVYCVPHEEATADSRDLEATAALTEVAAVSLEPTGTSTPGEEAAVLPASSDSERSASSVEGPSGALYARVARREARPARTRNEAGGLSLSPSPERRKPPPPDPATKPKVSWIHGKHSAAAA--APSPPPAGRKAAPSPSGRKRTPSNSSVQ---------------PPGLTEEAPGPASPTPPRARARGRGLGLSEPTDAGGPPRSAPEAASMLAAELRDKTRSLGRAE----------KPPPPQKAKRSVLPAATVRTASASEASGSEKAAASAPAPETPRKKTPIQKPPRKKSREAAGEPSRAGTAPGAS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D3ZBQ5-1", "uniprot_id": "D3ZBQ5_RAT", "id": "D3ZBQ5-1", "name": "", "aln": "MEGAGSRGAGPARRQGARGPP--------LLLLLWLLPGLAAAQDLNPRGRNVCRTPGSQVLTCCAGWRQLGDECGIAVCEGNSTCSENEVCVRPGECRCRHGYFGANCDTKCPRQFWGPDCKERCSCHPHGQCEDVTGQCTCHARRWGARCEHACQCQHGTCHPRSGACRCEPGWWGAQCASACYCSATSRCDPQTGACLCHAGWWGRSCNNQCSCNSSPCEQQSGRCQCRERTFGARCDRYCQCFRGRCHPVDGTCACDPGYRGKYCREPCPAGFYGLGCRRRCGQCKGQQPCTVVEGRCLTCEPGWNGTKCDQPCATGFYGEGCGHRCPPCRDGHACNHVTGKCTHCNAGWIGDRCETKCSNGTYGEDCAFVCSDCGSGHCDFQSGRCLCSPGVHGPHCNVTCPAGLHGVDCAQACSCHEESCDPVTGACHLETNQRKGVMGAGALLTLLLGLLLSLLGCCCACRGKDSARRPRPRRELTLGRKKAPQRFCGSFSRISMKLPRIPLRRQKLPKVVVAHHDLDNTLNCSFLEPPSGLEQPSPSWSSRASFSSFDTTDEGPVYCVPHEEATAENRDPEASASLTEVPAVSLAPMGTSVPGDEAAALPASSDSERSASSVEGPGGALYARVARREARPARTRCEAGGLSLSPSPERRKPPPPDPATKPKVSWIHGKQGAVAA--APSPPPAGRKAAPSPSGRKRTPSNMSVQ---------------PPGLTEEATGPASPTPPRARARGRGPGLLEPTDAGGPPRSAPEAASMLAAELRDKTRSLGRAE----------KPPPPQKAKRSVLPASTARAASASEASASEKVAASAPEPETPRKKTPIQKPPRKKSREAAGEPSRAGAAPGAS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q96GP6-1", "uniprot_id": "SREC2_HUMAN", "id": "Q96GP6-1", "name": "Scavenger receptor class F member 2", "aln": "MEGAGPRGAGPARRRGAGGPPSPLLPSLLLLLLLWMLPDTVAPQELNPRGRNVCRAPGSQVPTCCAGWRQQGDECGIAVCEGNSTCSENEVCVRPGECRCRHGYFGANCDTKCPRQFWGPDCKELCSCHPHGQCEDVTGQCTCHARRWGARCEHACQCQHGTCHPRSGACRCEPGWWGAQCASACYCSATSRCDPQTGACLCHAGWWGRSCNNQCACNSSPCEQQSGRCQCRERTFGARCDRYCQCFRGRCHPVDGTCACEPGYRGKYCREPCPAGFYGLGCRRRCGQCKGQQPCTVAEGRCLTCEPGWNGTKCDQPCATGFYGEGCSHRCPPCRDGHACNHVTGKCTRCNAGWIGDRCETKCSNGTYGEDCAFVCADCGSGHCDFQSGRCLCSPGVHGPHCNVTCPPGLHGADCAQACSCHEDTCDPVTGACHLETNQRKGVMGAGALLVLLVCLLLSLLGCCCACRGKDPTRRPRPRRELSLGRKKAPHRLCGRFSRISMKLPRIPLRRQKLPKVVVAHHDLDNTLNCSFLEPPSGLEQPSPSWSSRASFSSFDTTDEGPVYCVPHEEAPAESRDPEVPTVPAEAPAPSPVPLTTPASAEEAIPLPASSDSERSASSVEGPGGALYARVARREARPARARGEIGGLSLSPSPERRKPPPPDPATKPKVSWIHGKHSAAAAGRAPSPPPPGSEAAPSPSKRKRTPSDKSAHTVEHGSPRTRDPTPRPPGLPEEATALAAPSPPRARARGRGPGLLEPTDAGGPPRSAPEAASMLAAELRGKTRSLGRAEVALGAQGPREKPAPPQKAKRSVPPASPARAPPATETPGPEKAATDLPAPETPRKKTPIQKPPRKKSREAAGELGRAGAPTL--", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*****.********:** * ******:**. .*.*:**********:***** ******** ***************************************************** ******************************************************************************.***********:****************** *********** :************:****************** *****************.*****************************.********************:***************************:******************************.****.**********::*************************.**: ****************.:** **:*******:*:** *************************************:*************************************.*:.** *..: :*..* * * *....:** *****************.****************:* * *******************************:.*.** ******.* :****** ******: *.: ****.***.. *:*:********** ** ************************.********* **.********* **:..*:..*:*:...**.*:. * ************************ .***:.. ", "identical_positions": 719, "similar_positions": 77, "identity": "82.36%" }, { "cls_id": "homologset.agr.MGI:1858435", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "F1LV52-1", "uniprot_id": "F1LV52_RAT", "id": "F1LV52-1", "name": "G patch domain-containing protein 11", "aln": "----------------------RKENMAEEED-YMSDSFINVQEDVRPGVPMLRQIREARRKEEKQQQANLKNRQKSLKEEERE--RRDIGLKNALGCENKGFALLQKMGYKSGQALGKTGDGIVEPIPLNVKTGKSGIGHESLLKRKAEERLESYRRKIHMKN---QREEKAAEEFRMRLKSKQDELRLEGDLRRSQRACQQLDAQKNIQVPREAWYWMRPE--EETEEEEEE---------------------------------------KEEQDEDKCPSEDLSVLEKLQILTGYLREEHLYCIWCGTAYEDKEDLSSNCPGPTSADHD-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q3UFS4-1", "uniprot_id": "GPT11_MOUSE", "id": "Q3UFS4-1", "name": "G patch domain-containing protein 11", "aln": "--------------------------MTEEED-YMSDSFINVQEDVRPGVPMLRQIREARRKEEKQQQANLRNRQKSVKEEERE--RRDIGLKNALGCENKGFALLQKMGYKSGQALGKSGDGIVEPIPLNVKTGKSGIGHESSLKRKAEERLENYRRKIHMKN---QNEAKAAEEFRMRLKSKQDEMRLEGDLRRSQRACQQLDAQKNIQVPREAWYWLRPE--EETEEEEEEEE-------------------------------------KEEQDEDECPSEDLSVLEKLQILTGYLREEHLYCIWCGTAYEDKEDLSSNCPGPTSADHD-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8N954-1", "uniprot_id": "GPT11_HUMAN", "id": "Q8N954-1", "name": "G patch domain-containing protein 11", "aln": "MRSARSTALNRGEQRAVRYYSHMKLNMAEEED-YMSDSFINVQEDIRPGLPMLRQIREARRKEEKQQEANLKNRQKSLKEEEQE--RRDIGLKNALGCENKGFALLQKMGYKSGQALGKSGGGIVEPIPLNIKTGKSGIGHEASLKRKAEEKLESYRKKIHMKN---QAEEKAAEQFRMRLKNKQDEMKLEGDLRRSQRACQQLDVQKNIQVPREAWYWLRLE--EETEEDEEE----------------------------------------KEQDEDEYKSEDLSVLEKLQILTSYLREEHLYCIWCGTAYEDKEDLSSNCPGPTSADHD-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6DGZ0-1", "uniprot_id": "GPT11_DANRE", "id": "Q6DGZ0-1", "name": "G patch domain-containing protein 11", "aln": "--------------------------MADDEDDYMSDAFLNQISDVRPGVPMVKRVKEAIKKEALHKEKDIQNRQKSFKEQEKE--SREAALQSSIGSQNKGFALLQKMGYKAGQGLGKEGAGRVEPVPLNIKTDRGGIGMEEVKKRKADEELQNYRRKVHMKQ---HLEKKSIEDFRVRKRTEREERQTQGDLRKSQRACEQLDNQKGITVPRDCWYWPEVEKNEESELLEEEIK-------------------------------------TEESDEE----EELTPLDKLQFLTSYLRGVHYYCIWCGTAYNDEEDLGTNCPGDTAADHDD", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VI83-1", "uniprot_id": "Q9VI83_DROME", "id": "Q9VI83-1", "name": "G patch domain-containing protein 11", "aln": "--------------------------MSDEEEDYMSDKFLVGLQDVRPSLVHNRGRKRQIEVESKKDELKKRQRETAASSGNVDNVRLQQSLNKPISADNKGFQLLAKMGYKAGSGLGITSDARTEPVGITIKSGRGGLGREAAVAELALKRQKLRRAHLLNKAGIKSDEEVSTEAYRRRATHKAEERKLQYDIKRCQQTCESLDLKSAITEPDLDFFWPPKPKDEDESQSDAD----------------------------------------DPEVEVPPKQEPYSPSEQLELLTGYLRTAYCFCYWCGTHYDDAEDLGSNCPGLTRDEH--", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q06152-1", "uniprot_id": "YL271_YEAST", "id": "Q06152-1", "name": "Uncharacterized protein YLR271W", "aln": "-------------------------------------------------MEESKTKRKEDRIDLKNTPPQKKSKRDSTNDETAR-----TSLRSIMP---RGYKMMENMGYKEGETLGSNESALKEPIKVEINTKRRGIRAEKPDPSTMNDMQMSEQRFIKRES--EMKNNKRLKKIWYRIQKVAFEMMGDSDLYNPGEDPRDFNVLWRSYVMQLNEEVAKNDLNNHSNNDNEDKNNMIPMVNESLEASPAIKGEKFGRPSTLIDCDTSIIGSRITKDTELAELEELSIEKRITKLNIFLRSEKYYCFFCGIKYKDEGDLYEHCPGVNEDDHK-", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : :. . : : . :.:. : .. .*.. : :*: :: :**** *. ** . **: : ::: : *: * . : : : : : * * : *: . . ..:: :. . : : . * : .:: *. :** :* :** *.* ** :*** . :* ", "identical_positions": 31, "similar_positions": 65, "identity": "9.28%" }, { "cls_id": "homologset.agr.MGI:1858451", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9W130-1", "uniprot_id": "CP9C1_DROME", "id": "Q9W130-1", "name": "Cytochrome P450 9c1", "aln": "-----MVFVELSIFVAFIGLLLYKWSVYTFGYFSKRGVAHEKPIPLLGNIPWSVLMGK-ESYIKHSIDLHLRLKQHKVYGVFNLRDPLYYLSDPELIRQVGIKNFDTFTNHRKGITEGFND-----TSVISKSLLSLRDRRWKQMRSTLTPTFTSLKIRQMFELIHFCNVEAVDFVQRQL---DAG----TSELELKDFFTRYTNDVIATAAFGIQVNSFKDPNNEFFSIGQRISEFTFWG--GLKVMLYILMPKLMKALRVPVMDMNNVDYFKKLVFGAMKYR------KEQSIVRPDMIHLLMEAQRQFKAEQEGSAESAAQQDKAEFNDDDLLAQCLLFFSAGFETVATCLSFTSYELMMNPEVQEKLLAEILAVKEQLGEKPLDYDTLMGMKYLNCVVSESLRKWPPAFIVDRMCGSDFQLKDEEGEVVVN---LREDDLVHINVGALHHDPDNFPEPEQFRPERFDEEHKHEIRQFTYLPFGVGQRSCIGNRLALMEVKSLIFQLVLRYHLKPTDRTPADMMSSISGFRLLPRELFWCKLESRGPA------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9V6H1-1", "uniprot_id": "CP9H1_DROME", "id": "Q9V6H1-1", "name": "Probable cytochrome P450 9h1", "aln": "---MDQSMIALALFIILL-VLLYKWSVAKYDVFSERGVSHEKPWPLIGNIPLKAMIGG-MPVLKKMIELHTKHTGSPVYGIYALRDAVFFVRDPELIKLIGIKEFDHFVNHNS--MHNNIQ-----ESILSKSLISLRDGRWKEMRNILTPAFTGSKMRIMYDLIQSCSEEGVIHIQEQL---ELSQDA-SIELEMKDYFTRFANDVIATVAFGISINSFRRKDNEFFRIGQAMSRISAWS--VVKAMLYALFPRLMKVLRIQVLDTKNIDYFSSLVTAAMRYR------QEHKVVRPDMIHLLMEAKQQRLADL--SDKSKDELYYSEFTADDLLAQCLLFFFAGFEIISSSLCFLTHELCLNPTVQDRLYEEIISVHEELKGQPLTYDKLTKMKYLDMVVLEALRKWPPSISTDRECRQDIDLFDENGQKLFS---ARKGDVLQIPIFSLHHDPENFEDPEFFNPERFADGHALESR--VYMPFGVGPRNCIGNRMALMELKSIVYQLLLNFKLLPAKRTSRDLLNDIRGHGLKPKNGFWLKFEARQ--------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VG82-1", "uniprot_id": "CP9F2_DROME", "id": "Q9VG82-1", "name": "Probable cytochrome P450 9f2", "aln": "-----MLWEFFALFAIAA-ALFYRWASANNDFFKDRGIAYEKPVLYFGNMAG-MFLRK-RAMFDIVCDLYTKGGSKKFFGIFEQRQPLLMVRDPDLIKQITIKDFDHFINHRNVFATSSDDDPHDMSNLFGSSLFSMRDARWKDMRSTLSPAFTGSKMRQMFQLMNQVAKEAVDCLKQDD---SRVQ---ENELDMKDYCTRFTNDVIASTAFGLQVNSFKDRENTFYQMGKKLTTFTFLQ--SMKFMLFFALKGLNKILKVELFDRKSTQYFVRLVLDAMKYR------QEHNIVRPDMINMLMEARGIIQTEK--TKASAVR----EWSDRDIVAQCFVFFFAGFETSAVLMCFTAHELMENQDVQQRLYEEVQQVDQDLEGKELTYEAIMGMKYLDQVVNEVLRKWPAAIAVDRECNKDITF--DVDGQKVE---VKKGDVIWLPTCGFHRDPKYFENPMKFDPERFSDENKESIQPFTYFPFGLGQRNCIGSRFALLEAKAVIYYLLKDYRFAPAKKSCIPLELITSGFQLSPKGGFWIKLVQRN--------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "A0A2U8U1P3-1", "uniprot_id": "A0A2U8U1P3_DROME", "id": "A0A2U8U1P3-1", "name": "", "aln": "-----MLWEFLALFAIAT-ALFYRWASANNDFFKDRGIAYEKPVLYLGNMAG-MFLRK-RAMLDIVCDLYTKGGSGKFFGIFAQRQPLLMVRDPDLIKQITIKDFDHFINHRNEFDTSSDDDPHDMSNLFSSSLFSMRDARWKDMRSTLSPAFTGSKMRQMFQLMNQVAKEAVDCLKQDD---SRVQ---ENELDMKDYCTRFTNDVIASTAFGLQVNSFKDRENTFYQMGKKLTTFTFLQ--NMKFILLFALKSLNKILKVEIFDRKSTQYFVRLVLDAMKYR------QEHNIVRPDMINMLMEARGIIQTEK--TKASAVR----EWSDRDIVAQCFVFFFAGFETSAVLMCFTAHELMENQDVQQRLYEEVQQVDQDLEGKEL--------KYLDQVVSEVLRKWPPAIAFDRECNK--------------------------------------------------------------------------------EAKAVIYYLLKDYRFAPAKKSCIPLELISSGFQLSPKGGFWIKLVQRN--------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9V4I1-1", "uniprot_id": "CP9B2_DROME", "id": "Q9V4I1-1", "name": "Cytochrome P450 9b2", "aln": "-----MALIEICLALVVIGYLIYKWSTATFKTFEERKLYFEKPYPFVGNMAA-AALQK-SSFQRQLTEFYERTRQHKLVGFFNMRTPMITLNDPELIKKVCVKDFDHFPNHQPFITSN--------DRLFNDMLSVMRDQRWKHMRNTLTPVFTAAKMRNMFTLMNESFAECLQHLDSSS---KTLPGRKGFEVDMKVMCNKLSNDIIATTAFGLKVNSYDNPKNEFYEIGQSLVFSRGLQ--FFKFMLSTLVPKLFSLLKLTIFDSAKVDYFARLVVEAMQYR------EKHNITRPDMIQLLMEAK----------NESEDK-----WTDDEIVAQCFIFFFAAFENNSNLICTTTYELLYNPDVQERLYEEIVETKKALNGAPLTYDAVQKMTYMDMVISESLRKWTLAAATDRLCSKDYTLTDDDGTKLFD---FKVGDRINIPISGLHLDDRYFPEPRKFDPDRFSEERKGDMVPYTYLPFGVGPRNCIGNRYALMQVKGMLFNLLLHYKIEASPRTIKDLWGSASGFNFTPRSGFWMHLVPRK--------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9V4I0-1", "uniprot_id": "CP9B1_DROME", "id": "Q9V4I0-1", "name": "Cytochrome P450 9b1", "aln": "-----MSFVEICLVLATIGLLLFKWSTGTFKAFEGRNLYFEKPYPFLGNMAA-SALQK-ASFQKQISEFYNRTRHHKLVGLFNLRTPMIQINDPQLIKKICVKDFDHFPNHQTLNIPN--------ERLVNDMLNVMRDQHWRNMRSVLTPVFTSAKMRNMFTLMNESFAQCLEHLKSSQ---PIAAGENAFELDMKVLCNKLSNDVIATTAFGLKVNSFDDPENEFHTIGKTLAFSRGLP--FLKFMMCLLAPKVFNFFKLTIFDSTNVEYFVRLVVDAMQYR------EKHNITRPDMIQLLMEAK----------KESKDN-----WTDDEIVAQCFIFFFAAFENNSNLICTTAYELLRNLDIQERLYEEVKETQEALKGAPLTYDAAQEMTYMDMVISESLRKWTLSAAADRLCAKDYTLTDDEGTKLFE---FKAGDNINIPICGLHWDERFFPQPQRFDPERFSERRKKDLIPYTYLPFGVGPRSCIGNRYAVMQAKGMLYNLMLNYKIEASPRTTRDMWESARGFNIIPTTGFWMQLVSRK--------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9V675-1", "uniprot_id": "CP6G2_DROME", "id": "Q9V675-1", "name": "Probable cytochrome P450 6g2", "aln": "------MELVLLILVASLIGIAFLALQQHYSYWRRMGVREIRPKWIVGNLMGLLNMRMSPAEFISQLYNHPDAENEPFVGIHVFHKPALLLRDPEMVRNILVKDFAGFSNRYSSSDPKG-------DPLGSQNIFFLKNPAWKEVRLKLSPFFTGNRLKQMFPLIEEVGASLDAHLRQQP---LHNERMRCFDLEAKELCALYTTDVIATVAYGVSANSFTDPKCEFRRHGRSVFEFNLLR--AAEFTLVFFLPHLVPFVRFKVVPAEATRFLRKTINYVMSER------EKSGQKRNDLIDILIEFRRSTQLAKASGIKDQFV-----FEGDILVAQAVLFFTAGFESSSSTMAFAMYELAKDTDVQQRLREEIKDALVES-GGQVTLKMIESLEFMQMILLEVLRMYPPLPFLDRECTSGR---DYSLAPFHKKFVVPKGMPVYIPCYALHMDPQYFPQPRKFLPERFSPENRKLHTPYTYMPFGLGPHGCIGERFGYLQAKVGLVNLLRNHMITTSERTPHRMQLDPKAIITQAKGGIHLRLVRDALGV-----------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9V674-1", "uniprot_id": "CP6G1_DROME", "id": "Q9V674-1", "name": "Cytochrome P450 6g1", "aln": "----MVLTEVLFVVVAALVAL-YTWFQRNHSYWQRKGIPYIPPTPIIGNTKVVFKMENSFGMHLSEIYNDPRLKDEAVVGIYSMNKPGLIIRDIELIKSILIKDFNRFHNRYARCDPHG-------DPLGYNNLFFVRDAHWKGIRTKLTPVFTSGKVKQMYTLMQEIGKDLELALQRRG---EKNS--GSFITEIKEICAQFSTDSIATIAFGIRANSLENPNAEFRNYGRKMFTFTVAR--AKDFFVAFFLPKLVSLMRIQFFTADFSHFMRSTIGHVMEER------ERSGLLRNDLIDVLVSLR---KEAAAEPSKPHYA-----KNQDFLVAQAGVFFTAGFETSSSTMSFALYEMAKHPEMQKRLRDEINEALVEG-GGSLSYEKIQSLEYLAMVVDEVLRMYPVLPFLDREYESVEGQPDLSLKPFYD-YTLENGTPVFIPIYALHHDPKYWTNPSQFDPERFSPANRKNIVAMAYQPFGSGPHNCIGSRIGLLQSKLGLVSLLKNHSVRNCEATMKDMKFDPKGFVLQADGGIHLEIVNDRLYDQSAPSLQ----", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VRB3-1", "uniprot_id": "CP6V1_DROME", "id": "Q9VRB3-1", "name": "Probable cytochrome P450 6v1", "aln": "----MVYSTNILLAIVTILTGVFIWSRRTYVYWQRRRVKFVQPTHLLGNLSRVLRLEESFALQLRRFYFDERFRNEPVVGIYLFHQPALLIRDLQLVRTVLVEDFVSFSNRFAKCDGRS-------DKMGALSLFLAKQPEWREIRTRLAPAFAGAKLKQMFSLMEEIGCDLEWYLKRLTRDLRRGDAERGAIVSIKDVCDLYNTDMIASIAFGLRSYSLRNTQSEIGSHCQDLFRPNVRR--IIDLFVIFYLPKLVPLLRPKLFTEPHAEFLRRVIQLVIEER------ERGGDLRNDLIEMLLTLK---KEADLQQDKSHFT-----HHRDFLAAQAASFEVAGIETCSASMSFALYELAKQPLMQSRLRREIREAFASNPNGRLTYEAVARMEFLDMVVEETLRKYPIVPLLERECTPINKKRFYSLRPHAECYTRR-GMPVFISNLAIHHDPKYWPDPDRFDPERFSAANKALQAPMSYMPFGAGPRNCIGMQIGLLQIKLGLVYFLHQHRVEICDRTVERIQFDAKFALLASEQRIYLKV--DCL-------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9V4U9-1", "uniprot_id": "C6A13_DROME", "id": "Q9V4U9-1", "name": "Probable cytochrome P450 6a13", "aln": "-------MLTLLVLVFTVGLLLYVKLRWHYSYWSRRGVAGERPVYFRGNMSGLGRDLHWTDINLR-IYRKFRG-VERYCGYFTFMTKSLFIMDLELIRDIMIRDFSSFADRGLFHNVRD-------DPLTG-NLLFLDGPEWRWLRQNLTQVFTSGKMKFMFPNMVEVGEKLTQACRLQVG-----------EIEAKDLCARFTTDVIGSCAFGLECNSLQDPESQFRRMGRSVTQEPLHS--VLVQAFMFAQPELARKLRFRLFRPEVSEFFLDTVRQTLDYR------RRENIHRNDLIQLLMELG-------EEGVKDALS-----FEQ--IAAQALVFFLAGFDTSSTTMSFCLYELALNPDVQERLRVEVLAVLKRN-NQKLTYDSVQEMPYLDQVVAETLRKYPILPHLLRRSTKEYQIPNSNL-------ILEPGSKIIIPVHSIHHDPELYPDPEKFDPSRFEPEEIKARHPFAYLPFGEGPRNCIGERFGKLQVKVGLVYLLRDFKFSRSEKTQIPLKFSSRNFLISTQEGVHLRMEGLERP------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P05183-1", "uniprot_id": "CP3A2_RAT", "id": "P05183-1", "name": "Cytochrome P450 3A2", "aln": "MDLLSALTLETWVLLAVILVLLYRLGTHRHGIFKKQGIPGPKPLPFLGTVLN-------YYKGLGRFDMECYKKYGKIWGLFDGQTPVFAIMDTEMIKNVLVKECFSVFTNRRDFGPVG---------IMGKAVSVAKDEEWKRYRALLSPTFTSGRLKEMFPIIEQYGDILVKYLKQEAE--------TGKPVTMKKVFGAYSMDVITSTSFGVNVDSLNNPKDPFVEKTKKLLRFDFFDPLFLSVVLFPFLTPIYEMLNICMFPKDSIAFFQKFVHRIKETR-----LDSKHKHRVDFLQLMLNAHNNSKDEV----SHKAL------SDVEIIAQSVIFIFAGYETTSSTLSFVLYFLATHPDIQKKLQEEIDGALPSK--APPTYDIVMEMEYLDMVLNETLRLYPIGNRLERVCKKDIELDGLFIP---------KGSVVTIPTYALHHDPQHWPKPEEFHPERFSKENKGSIDPYVYLPFGNGPRNCIGMRFALMNMKLALTKVLQNFSFQPCKETQIPLKLSRQAILE-PEKPIVLKVLPRDAVINGA--------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9JMA7-1", "uniprot_id": "CP341_MOUSE", "id": "Q9JMA7-1", "name": "Cytochrome P450 3A41", "aln": "MNLFSALSLDTWVLLAIILVLLYRYGTRTHGLFKKQGIPGPKPLPFLGTVLN-------YYKGLWKFDMECYEKYGKTWGLFDGQMPLFVITDPEMIKNVLVKECFSVFTNRREFGPVG---------IMSKAISISKDEEWKRYRALLSPTFTSGKLKEMFPVIEQYGDILVKYLMQEAE--------KGKPVTMKDVLGAYSIDVITSTSFGVNVDSLNNPEDPFVEKAKGILRVDFFDPLVFSVVLFPFLTPVYEMLNICMFPKDSIEFFKKFVNRMKESR-----LDSKQKHRVDFLQLMMNAHNNSKDKD----SHKAL------SDMEITAQSIVFIFAGYETTSSTLSFTLYCLATHPDIQKKLQEEIDETLPNK--APPTYDTVMEMEYLDMVLNETLRLYPIGNRLERFCKKDVELNGVYIP---------KGSTVMIPSYALHHDPQHWPEPEEFQPERFSKENKGSIDPYLYMPFGIGPRNCIGMRFAFMTMKLALTKVMQNFSFQPCQETQIPLKLSRQGLLQ-PEKPIVLKVVPRDVVITGA--------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P20815-1", "uniprot_id": "CP3A5_HUMAN", "id": "P20815-1", "name": "Cytochrome P450 3A5", "aln": "MDLIPNLAVETWLLLAVSLVLLYLYGTRTHGLFKRLGIPGPTPLPLLGNVLS-------YRQGLWKFDTECYKKYGKMWGTYEGQLPVLAITDPDVIRTVLVKECYSVFTNRRSLGPVG---------FMKSAISLAEDEEWKRIRSLLSPTFTSGKLKEMFPIIAQYGDVLVRNLRREAE--------KGKPVTLKDIFGAYSMDVITGTSFGVNIDSLNNPQDPFVESTKKFLKFGFLDPLFLSIILFPFLTPVFEALNVSLFPKDTINFLSKSVNRMKKSR-----LNDKQKHRLDFLQLMIDSQN-SKETE----SHKAL------SDLELAAQSIIFIFAGYETTSSVLSFTLYELATHPDVQQKLQKEIDAVLPNK--APPTYDAVVQMEYLDMVVNETLRLFPVAIRLERTCKKDVEINGVFIP---------KGSMVVIPTYALHHDPKYWTEPEEFRPERFSKK-KDSIDPYIYTPFGTGPRNCIGMRFALMNMKLALIRVLQNFSFKPCKETQIPLKLDTQGLLQ-PEKPIVLKVDSRDGTLSGE--------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1N818-1", "uniprot_id": "A0A8M1N818_DANRE", "id": "A0A8M1N818-1", "name": "unspecific monooxygenase", "aln": "----MFFSAETWTLLAFLVALLVIYGSWPHRYFKKLGIPGPKTIPFFGTMLR-------YKDGFHVFDMDCFEKYGRIWGIYDGRQPVLCIMDQTIIKTVLIKECYSLFTNRRNFRLNG---------ALYDAVSIAEDDDWRRIRSVLSPSFTSGRLKEMFGIMKKHSHILVDSMGKTAK--------RGESADIKEFFGAYSMDVVTSTAFSVDIDSLNNPKDPFVTNIKKMLKFDLLNPLFLLIAFFPFMAPVLEKMDFALFPTSVTDFFYAALQKIKSDRDTKTVAKDNTKKRVDFLQLMVDSQTGVKHKSDGEHTEKGL------SDHEILSQSMIFIFAGYETSSSTLSFLFYNLATNPETMKKLQEEIDETFPNQ--APVDYETLMSMDYLDAALSESLRLYPVAARLERVCKKTVEINGLLIP---------KDLVVMVPTYALHRDPDYWSEPESFKPERFTKGNKESIDPYMYMPFGLGPRNCIGMRFAQVTMKLAIVEILQRFDVSVCDETQVPLELGFNGLLS-PKDPIKLKLQPRKLSQSPDVCNNNQKS", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : . *. * . : * ::: : :.: . . : *: * *: *:. ::: *: : * * : ::.: * . : : . . : . .. :: : * * *::.::: : :*. * *. : : :. : : . .:* *: . :: : * ** :. * * : .: . . : : . . .. ", "identical_positions": 24, "similar_positions": 79, "identity": "4.26%" }, { "cls_id": "homologset.agr.MGI:1858493", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D4A2A5-1", "uniprot_id": "D4A2A5_RAT", "id": "D4A2A5-1", "name": "Beta-1,4-galactosyltransferase", "aln": "MSRLLGG-TLERVCKAVLLLCLLHFLVAVILYFDVYAQHLAFFSRFSTRSPAHALYPAASSS---TNCSRPNTTAAS---SGLPEVPSARPG-----PTAPVIPPCPDVPPGLVGRVVIEFTSPMPLERVQRE-----------------------------------NPGVLLGGRYSPPDCTPAQTVAVIIPFRHREHHLRYWLHYLHPMLRRQRLRYGVYVINQHGEETFNRAKLLNVGFLEALKEDATYDCFIFSDVDLVPMDDRNLYRCGDQPRHFAIAMDKFGFRLPYASYFGGVSGLSKAQFLRINGFPNEYWGWGGEDDDIFNRISLTGMKISRPDVRIGRYRMIKHDRDKHNEPNPQRFNKIQNTKMSMKWDGIGSVRYRVLEVSRQPLFTNITVDIGQPMSWLTQG", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9Z2Y2-1", "uniprot_id": "B4GT2_MOUSE", "id": "Q9Z2Y2-1", "name": "Beta-1,4-galactosyltransferase 2", "aln": "MSRLLGG-TLERVCKAVLLLCLLHFLVAVILYFDVYAQHLAFFSRFSTRSPAHALYPAASSS---TNCSRPNATAAS---SGLPEVPSARPG-----PTAPVIPPCPDVPPGLVGRVVIEFTSPMPLERVQRE-----------------------------------NPGVLLGGRYSPPDCTPAQTVAVIIPFRHREHHLRYWLHYLHPMLRRQRLRYGVYVINQHGEETFNRAKLLNVGFLEALKEDAAYDCFIFSDVDLVPMDDRNLYRCGDQPRHFAIAMDKFGFRLPYASYFGGVSGLSKAQFLRINGFPNEYWGWGGEDDDIFNRISLTGMKISRPDVRIGRYRMIKHDRDKHNEPNPQRFNKIQNTKMSMKWDGIGSVRYRVLEVSRQPLFTNITVDIGQPMSWLTQG", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O60909-1", "uniprot_id": "B4GT2_HUMAN", "id": "O60909-1", "name": "Beta-1,4-galactosyltransferase 2", "aln": "MSRLLGG-TLERVCKAVLLLCLLHFLVAVILYFDVYAQHLAFFSRFSARGPAHALHPAASSSSSSSNCSRPNATASS---SGLPEVPSALPG-----PTAPTLPPCPDSPPGLVGRLLIEFTSPMPLERVQRE-----------------------------------NPGVLMGGRYTPPDCTPAQTVAVIIPFRHREHHLRYWLHYLHPILRRQRLRYGVYVINQHGEDTFNRAKLLNVGFLEALKEDAAYDCFIFSDVDLVPMDDRNLYRCGDQPRHFAIAMDKFGFRLPYAGYFGGVSGLSKAQFLRINGFPNEYWGWGGEDDDIFNRISLTGMKISRPDIRIGRYRMIKHDRDKHNEPNPQRFTKIQNTKLTMKRDGIGSVRYQVLEVSRQPLFTNITVDIGRPPSWPPRG", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A8WHZ0-1", "uniprot_id": "A8WHZ0_DANRE", "id": "A8WHZ0-1", "name": "Beta-1,4-galactosyltransferase", "aln": "MSRLMLGRTLERICKAVLLLCLVHFLIMMILYFDVYSQRFDIFSRFNNGRGANNSRGAHHYYYN-FSSGRPNTTFASYLATADHLLPSTKPEANHTPPTPKPLPPCPEVPLGLVGRLLIEFSSQITLERVQRE-----------------------------------NPNVTEGGKYTPPDCRPKQKVAIIIPFRHRDNHLKYWLHYLHPVLRRQKIDYGIYIINQLGEDTFNRAKLLNVGYTEAIK-DAEYNCFIFSDVDLIPMDDRNLYHCYDQPRHFAIAMDKFGFRLPYAGYFGGVSGLSKKQFLKINGFPNEYWGWGGEDDDIYNRITLNGMKVSRPDVRIGRYRMIKHERDKHNEPNPQRFSKIQNTKNTMRKDGISSLMYRVVSIKKYPLYTNISVEIGKPPPRPLKG", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q7KN92-1", "uniprot_id": "B4GTA_DROME", "id": "Q7KN92-1", "name": "Beta1,4-N-acetylgalactosaminyltransferase A", "aln": "-MYLFTKANLIRFLAGAICLLLVLNFVGFRSDGGSATSLSKLSIRRVHKYAHIYGNASSDGAGGSEASRLPASPLALSKDRERDQELNGGPN-----STIRTVIATANFTSIPQDLTRFLLGTKKFLPPRQKSTSALLANCTDPDPRDGGPITPNTTLESLDVIEAELGPLLRPGGAFEPENCNAQHHVAIVVPFRDRYAHLLLFLRNIHPFLMKQRIAYRIFIVEQTNGKPFNRAAMMNIGYLEALK-LYQWDCFIFHDVDLLPLDDRNLYNCPRQPRHMSVAIDTLNFRLPYRSIFGGVSAMTREHFQAVNGFSNSFFGWGGEDDDMSNRLKHANLFISRYPVNIARYKMLKHQKE---KANPKRYENLQNGMSKIEQDGINSIKYSIYSIKQFPTFTWYLAELKNSERKS---", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VAQ8-1", "uniprot_id": "B4GTB_DROME", "id": "Q9VAQ8-1", "name": "Beta1,4-N-acetylgalactosaminyltransferase B", "aln": "--------MFVRLWVRSFHKYDLLIAIGLIT----LIVYLCLPFRFASHYDYIEESKIEG---------------ALVPQVTRNVSQQEVFE-----CTYSEIIAEN----------RFVYHLAHYHDAVQR------------------------------------GAEIRPGGEFRPEGCQARYSTAIIVPYRQREEQLHAFLTYMHNYLPQQLIHYRIFLVEQFDHKPFNRAMLFNIG-AQVAA-EYGFPCLILHDVDLLPLNSGQIYACSERPRHMSSALDHWRFRLPYRGLFGGVVAINTAQYQQINGMSNLYYGWGGEDDDLYERLQALNIDICRFAMEFSKYTMLKHKQE---QPNANRVALLRSATLRQHADGLNSLVYTEMERRMHSLFTHILVDT----------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : *. : : : . : * : . * : . : *: .. : ** : * .* . .*:::*:*.* :* :* :* * :* : * :::::* . ..**** ::*:* :. : *:*: ****:*::. ::* * :***:: *:* ***** . **** .:. :: :**:.* ::********: :*: .: :.* :.:.:* *:**.:: :.*.:* ::. . **:.*: * . . :* .: ", "identical_positions": 72, "similar_positions": 99, "identity": "17.31%" }, { "cls_id": "homologset.agr.MGI:1858494", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q792S6-1", "uniprot_id": "BOK_RAT", "id": "Q792S6-1", "name": "Bcl-2-related ovarian killer protein", "aln": "MEVLRRSSVFAAEIMDAFDRSPTDKELVAQAKALGREYVHARLLRAGLSWSAPERASPAPGGRLAEVCTVLLRLGDELEQIRPSVYRNVARQLHIPLQSEPVVTDAFLAVAGHIFS-----------AGITWGKVVSLYSVAAGLAVDCVRQAQPAMVHALVDCLGEFVRKTLATWLRRRGGWTDVLKCVVSTDPGFRSHWLVATLCSFGRFLKAAFFLLLPER", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O35425-1", "uniprot_id": "BOK_MOUSE", "id": "O35425-1", "name": "Bcl-2-related ovarian killer protein", "aln": "MEVLRRSSVFAAEIMDAFDRSPTDKELVAQAKALGREYVHARLLRAGLSWSAPERASPAPGGRLAEVCTVLLRLGDELEQIRPSVYRNVARQLHIPLQSEPVVTDAFLAVAGHIFS-----------AGITWGKVVSLYSVAAGLAVDCVRQAQPAMVHALVDCLGEFVRKTLATWLRRRGGWTDVLKCVVSTDPGFRSHWLVATLCSFGRFLKAAFFLLLPER", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9UMX3-1", "uniprot_id": "BOK_HUMAN", "id": "Q9UMX3-1", "name": "Bcl-2-related ovarian killer protein", "aln": "MEVLRRSSVFAAEIMDAFDRSPTDKELVAQAKALGREYVHARLLRAGLSWSAPERAAPVPG-RLAEVCAVLLRLGDELEMIRPSVYRNVARQLHISLQSEPVVTDAFLAVAGHIFS-----------AGITWGKVVSLYAVAAGLAVDCVRQAQPAMVHALVDCLGEFVRKTLATWLRRRGGWTDVLKCVVSTDPGLRSHWLVAALCSFGRFLKAAFFVLLPER", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6DC66-1", "uniprot_id": "BOKA_DANRE", "id": "Q6DC66-1", "name": "Bcl-2-related ovarian killer protein homolog A", "aln": "MEMLRRSSVFAAEVMEVFDRSPTDKELVSQSKVLCRDYIHSRLHRAGIGWSKPEHGS---GGTLAEVSSVLLWLGDELEYLRPNVYRNVARQLNITIASENIVSDAFLAVAAEIFSTEYSRKGLEKHKGVTWGKIVSLYAVAGALAVDCVRNGHPAMVHTIVDCMGEFVRKSLASWLKKRGGWADITKCVVSTDPSFHSHWLVTAACACGHYLKAVVFYLLREK", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q7T381-1", "uniprot_id": "BOKB_DANRE", "id": "Q7T381-1", "name": "Bcl-2-related ovarian killer protein homolog B", "aln": "MNVFARSSVLAAEMIDVFDRTHTEKELVFQSKELCRDFIHSRITREGLSWSKVELDLPEPRGVLVDVSVVLLKLGDELECMRPYVYRNIAKQLNISVSVEAVVSDAFLSVATEVIA-----------MGITWGKVVAIYAVAAGLAVDCVRLGHPVMVHTIVDSLGEFVRRSLVPWLKKRGGWVDILKCVVNMDSRAHVHWLSTAVLTWREFIKTMYVYLTK--", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*::: ****:***:::.***: *:**** *:* * *:::*:*: * *:.** * *.:*. *** ****** :** ****:*:**:*.: * :*:****:** .::: *:****:*::*:**..******* .:*.***::**.:*****::*..**::****.*: ****. *. : *** :: : .::*: . * ", "identical_positions": 101, "similar_positions": 67, "identity": "45.09%" }, { "cls_id": "homologset.agr.MGI:1858496", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O88450-1", "uniprot_id": "DEAF1_RAT", "id": "O88450-1", "name": "Deformed epidermal autoregulatory factor 1 homolog", "aln": "MEDSDS-AAKQLGLAEAAAVAAAAAVAAAAAAAAESEAEEPVLSRDEDSEEDADSEAERETRRVTAVAVMAAESGHMDMGTEALPS--PDE-AAAAAAFAEVTTVTVAN-----VGSSADNVFTTSVANAASISGHVLSGRTALQIG--------DSLNTEKATLIVVHTDGSIVETTGLKGPAAPLTPGPQSPPTPLAPGQEKGGTKYNWDP-SVYDSELPVRCRNISGTLYKSRLGSGGRGRCIKQGENWYSPTEFEAMAGRASSKDWKRSIRYAGRPLQCLIQDGILNPHAASCTCAACCDDMT------------------LSGPVRLFVPYKRRKKENELPTTPVKK---DSPKNITLLPATAATTFTVTPSGQITTSGALTFDRASTVEATAVISESPAQGDVFAGATVQEAGVQPPCRVGHPEPHYPGYQDSCQIAPFPEAALPTSHPKIVLTSLPALAVPPSTPTKAVSPTVVSGLEMSEHRSWLYLEEMVNSLLNTAQQLKTLFEQAKQASSCREAAVT-------------QARMQVDAERK--------EQSCVNCGREAMSECTGCHKVNYCSTFCQRKDWKDHQHVCGQS-ASVTVQADDVHVEESVIEKVAV", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9Z1T5-1", "uniprot_id": "DEAF1_MOUSE", "id": "Q9Z1T5-1", "name": "Deformed epidermal autoregulatory factor 1 homolog", "aln": "MEDSDS-AAKQLGLAEAAAVAAAAAVAAAAAAAAESEAEEPVLSRDEDSEEDADSEAERETRRVTAVAVMAAESGHMDMGTEALPS--PDEAAAAAAAFAEVTTVTVAN-----VGSSADNVFTTSVANAASISGHVLSGRTALQIG--------DSLNTEKATLIVVHTDGSIVETTGLKGPAAPLTPGPQSPPTPLAPGQEKGGTKYNWDP-SVYDSELPVRCRNISGTLYKSRLGSGGRGRCIKQGENWYSPTEFEAMAGRASSKDWKRSIRYAGRPLQCLIQDGILNPHAASCTCAACCDDMT------------------LSGPVRLFVPYKRRKKENELPTTPVKK---DSPKNITLLPATAATTFTVTPSGQITTSGALTFDRASTVEATAVISESPAQGDVFAGATVQEAGVQPPCRVGHPEPHYPGYQDSCQIAPFPEAALPTSHPKIVLTSLPALAVPPSTPTKAVSPTVVSGLEMSEHRSWLYLEEMVNSLLNTAQQLKTLFEQAKQASSCREAAVT-------------QARMQVDTERK--------EQSCVNCGREAMSECTGCHKVNYCSTFCQRKDWKDHQHVCGQS-ASVTVQADDVHVEESVIEKVAV", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O75398-1", "uniprot_id": "DEAF1_HUMAN", "id": "O75398-1", "name": "Deformed epidermal autoregulatory factor 1 homolog", "aln": "MEDSDS-AAKQLGLAEAAAVAAAAAVAAAAAAAAGGEAEEPVLSRDEDSEEDADSEAERETPRVTAVAVMAAEPGHMDMGAEALPG--PDE-AAAAAAFAEVTTVTVAN-----VGAAADNVFTTSVANAASISGHVLSGRTALQIG--------DSLNTEKATLIVVHTDGSIVETTGLKGPAAPLTPGPQSPPTPLAPGQEKGGTKYNWDP-SVYDSELPVRCRNISGTLYKNRLGSGGRGRCIKQGENWYSPTEFEAMAGRASSKDWKRSIRYAGRPLQCLIQDGILNPHAASCTCAACCDDMT------------------LSGPVRLFVPYKRRKKENELPTTPVKK---DSPKNITLLPATAATTFTVTPSGQITTSGALTFDRASTVEATAVISESPAQGDVFAGATVQEASVQPPCRASHPEPHYPGYQDSCQIAPFPEAALPTSHPKIVLTSLPALAVPPPTPTKAAPPALVNGLELSEPRSWLYLEEMVNSLLNTAQQLKTLFEQAKHASTYREAATN-------------QAKIHADAERK--------EQSCVNCGREAMSECTGCHKVNYCSTFCQRKDWKDHQHICGQS-AAVTVQADEVHVAESVMEKVTV", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M2BLH6-1", "uniprot_id": "A0A8M2BLH6_DANRE", "id": "A0A8M2BLH6-1", "name": "", "aln": "MDATEEPATKELELGDASESASTG---------------EPVGS-------DTESEAEVAT-----MTVMG-EAGTIDI-TESLPN--PDD---AETAFAEVTAVTVGD-----VQSSDDSVFTSAVATATSIPEHVLTGRATLQIG--------NTLSTQKATLIVVHTDGSIVDATSLKATGTPMTPGPQTPNTPLASGHDKDVSKYNWDP-SVYDNELPVRCRNTSGLLYKNRLGSGGKGRCIKHNNSWYTPTEFEGMSGRASSKDWKRSIRYAGRPLQCLIQERILNPHAASCTCAACCDDLSTVSDTCTKEGSYGQESLSMTGPVRLFVPYKRRKKDNERAASPDNKKEIQSPKNITLAPG---ATFTVSPSGQISTSGTLSFDRSASGETASIISDSPAAPDVYTNTTVLTT-------------------------------LP------ALAVVPQQAVVQSKPPPAG--TLLNGLETGEQRTWLYLEEMANTLLSNVQQLKVLIAQAKQASQSGAHATISPDKNSSGRKESFQSQFSLTEEPEGKITEIIIKHTCVNCGREASCECTGCHKVHYCSGFCQRKDWKEHQLNCCQPNTSVSIQED----TQMELDKGKA", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q24180-1", "uniprot_id": "DEAF1_DROME", "id": "Q24180-1", "name": "Deformed epidermal autoregulatory factor 1", "aln": "MEQVDSSTELHLNRKDLAALAEDVVKEEVILESSSHHHHHHHHQLDTKVRMVTSSSNDNSGSGGASGGTSGAGGGNGGGGVVSVPVSLPIGSMITGTTFNVITPDQLPPHFKPMLCVDNNGYLSGSTVSMGNDLKTIVIQQQQTQPGGGGGGANNAGTNTTATNTIGLNHDGSGSNNSHDSLATLEHAAGGASGVGGGGGGTGGGSSGWSENPSTQHNEVFQIRCKTTCAELYRSKLGSGGRGRCVKYKDKWHTPSEFEHVCGRGSSKDWKRSIKYGGKSLQSLIDEGTLTPHATNCSCTVCCDDEAG---------------ESASGPVRLFTPYKRRKRNQTDLDMESGP---KRKRNTHHSNNNNSNTNNNNTSGSGANN-CVDVTAAVAAATASVVDEN----NMFLSEENITSKDEPWAALNDSLDTSTELVDQSQMG----NTYERETFVVNINDGSSIAVLDTSQSMKNIEHVYCTMVKATNDFKRMLNDMKQSFERRIEVLQKERDAAVSAMRVQVHADID------------DPNISGSLHGN----EIISAKKCANCNREALAECSLCRKTPYCSEFCQRKDWNAHQVECTRNPQTTTQQVMLLIDDQS-------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*: :. : .* : : * . . :.*. : . . * . . ::* * : ::* :*. : : :. :: :... . :: : * * .* :. * :: *** : : . . :.* : . * . : :. :* : ::. : :**:. .. **:.:*****:***:* :.*::*:*** :.**.*********:*.*:.**.**:: *.***:.*:*:.**** : :******.******::: . :* * . ..**. :.. : . : : :::::.:. ::: . : : . ** .. . : : . *::* ::: : *: * * * :..: . : :.*.**.*** .**: *:*. *** *******: ** * : :.: * : ", "identical_positions": 112, "similar_positions": 159, "identity": "17.89%" }, { "cls_id": "homologset.agr.MGI:1858497", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I6ASC6-1", "uniprot_id": "A0A8I6ASC6_RAT", "id": "A0A8I6ASC6-1", "name": "Immunoglobulin superfamily DCC subclass member 4", "aln": "MARADTGRG--LLALTFCLLSARGELPLPQETTVQLSCDEGPLRVVLGPEQAVVLDCTLGAAAAGPPTTVTWSKDGDVVLERDNLHLLPNGSLRLSSPLEPEDSDDEEALSVWKVIEGSYSCLAHGPLGVVASQVAVVKLATLEDFSLHPESQTVEENGTARFECHTEGLPAPIITWEKDQVTVTEEPRLITLPNGVLQILDVQDSDAGSYRCVATNSARQRFSQEALLSVALRGSLEATRGQDVVIVAAPENTTVVSGQSVVLECVASADPTPFVSWVRQDGKPISTDVIVLGRTNLLIASAQPRHSGVYVCRANKPRTRDFATAAAELRVLAAPAISQAPEALSRTRASTARFVCRASGEPRPTLHWLHDGAPLRPNGRVKVQGGGGSLVITQIGLQDSGYYQCVAENSAGTACAAAPLAVVVREGLPSAPTRVKATPLSSSAVLVAWERPELHSEQIIGFSLHYQKARGVDNVEYQFAVNNDTTELQVRDLEPNTDYEFYVVAYSQLGASRTSSPALVHTLDDVPSAAPQLSLSSPNPSDIRVAWLPLPSSLSNGQVVKYKIEYGSGKEEDQVFSTEVPGNETQLTLNSLQPNKVYRVRISAGTGAGYGVPSQWMQHRTPGAHNQSHVPFAPAELKVRAKMESLVVSWQPPPHPTQISGYKLYWREVGTEEEADGDRPPGGRGDQAWDVGPVRLKKKVKQYELTQLVPGRLYEVKLVAFNKHEDGYAAVWKGKTEKAPTPDLPIQRGPPLPPAHVHAESNSSTSIWLRWKKPDFTTVKIVNYTVRFGPWGLRNASLVTYYTSSGEDILIGGLKPFTKYEFAVQSHGVDMDGPFGSVVERSTLPDRPSTPPSDLRLSPLTPSTVRLHWCPPTEPNGEIVEYLILYSNNHTQPEHQWTLLTTEGNIFSAEVHGLESDTRYFFKMGARTEVGPGPFSRLQDVITLQETFSDSLDVHSVTGIIVGVCLGLLCLLACMCAGLRRSSHREALPGLSSTATAGNPALYSRARLGPPSVPAAHELESLVHPRPQDWSPPPSDVEDKAKVHSLMGGSVSDCRGHSKRKISWAQAGGPNWAGSWAGCELPQGSGPRPALTRALLPPAGTGQTLLLQALVYDAIKSNGRKKPSPACRNQVEAEVIVHSDFSASKGCPDLHLQDLEPEEALPAEVLPPTAGVVDLSQGADWLGRELEECQPATTGPERLTCLPEAASASCSCSDLQPSSAVEEAPGKGCQPKALCPLEISPSLPRAPVSSAQVP", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9EQS9-1", "uniprot_id": "IGDC4_MOUSE", "id": "Q9EQS9-1", "name": "Immunoglobulin superfamily DCC subclass member 4", "aln": "MARADTGRG--LLVLTFCLLSARGELPLPQETTVKLSCDEGPLQVILGPEQAVVLDCTLGATAAGPPTRVTWSKDGDTVLEHENLHLLPNGSLWLSSPLEQEDSDDEEALRIWKVTEGSYSCLAHSPLGVVASQVAVVKLATLEDFSLHPESQIVEENGTARFECHTKGLPAPIITWEKDQVTVPEESRLITLPNGVLQILDVQDSDAGSYRCVATNSARQRFSQEASLTVALRGSLEATRGQDVVIVAAPENTTVVSGQSVVMECVASADPTPFVSWVRQDGKPISTDVIVLGRTNLLIASAQPRHSGVYVCRANKPRTRDFATAAAELRVLAAPAISQAPEALSRTRASTARFVCRASGEPRPALHWLHDGIPLRPNGRVKVQGGGGSLVITQIGLQDAGYYQCVAENSAGTACAAAPLAVVVREGLPSAPTRVTATPLSSSSVLVAWERPELHSEQIIGFSLHYQKARGVDNVEYQFAVNNDTTELQVRDLEPNTDYEFYVVAYSQLGASRTSSPALVHTLDDVPSAAPQLTLSSPNPSDIRVAWLPLPSSLSNGQVLKYKIEYGLGKE-DQVFSTEVPGNETQLTLNSLQPNKVYRVRISAGTGAGYGVPSQWMQHRTPGVHNQSHVPFAPAELKVRAKMESLVVSWQPPPHPTQISGYKLYWREVGTEEEADGDRPPGGRGDQAWDVGPVRLKKKVKQYELTQLVPGRLYEVKLVAFNKHEDGYAAVWKGKTEKAPTPDLPIQRGPPLPPAHVHAESNSSTSIWLRWKKPDFTTVKIVNYTVRFGPWGLRNASLVTYYTSSGEDILIGGLKPFTKYEFAVQSHGVDMDGPFGSVVERSTLPDRPSTPPSDLRLSPLTPSTVRLHWCPPTEPNGEIVEYLILYSNNHTQPEHQWTLLTTEGNIFSAEVHGLESDTRYFFKMGARTEVGPGPFSRLQDVITLQKTFSDSLDVHAVTGIIVGVCLGLLCLLACMCAGLRRSSHREALPGLSSSGTPGNPALYTRARLGPPSVPAAHELESLVHPRPQDWSPPPSDVEDKAEVHSLMGGSVSDCRGHSKRKISWAQAGGPNWAGSWAGCELPQGSGPRPALTRALLPPAGTGQTLLLQALVYDAIKSNGRKKPSPACRNQVEAEVIVHSDFGASKGCPDLHLQDLEPEEPLTAETLPSTSGAVDLSQGADWLGRELGGCQPTTSGPERLTCLPEAASASCSCSDLQPSTAIEEAPGKSCQPKALCPLTVSPSLPRAPVSSAQVP", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8TDY8-1", "uniprot_id": "IGDC4_HUMAN", "id": "Q8TDY8-1", "name": "Immunoglobulin superfamily DCC subclass member 4", "aln": "MARGDAGRGRGLLALTFCLLAARGELLLPQETTVELSCGVGPLQVILGPEQAAVLNCSLGAAAAGPPTRVTWSKDGDTLLEHDHLHLLPNGSLWLSQPLAPNGSD-ESVPEAVGVIEGNYSCLAHGPLGVLASQTAVVKLATLADFSLHPESQTVEENGTARFECHIEGLPAPIITWEKDQVTLPEEPRLIVLPNGVLQILDVQESDAGPYRCVATNSARQHFSQEALLSVAHRGSLASTRGQDVVIVAAPENTTVVSGQSVVMECVASADPTPFVSWVRQDGKPISTDVIVLGRTNLLIANAQPWHSGVYVCRANKPRTRDFATAAAELRVLAAPAITQAPEALSRTRASTARFVCRASGEPRPALRWLHNGAPLRPNGRVKVQGGGGSLVITQIGLQDAGYYQCVAENSAGMACAAASLAVVVREGLPSAPTRVTATPLSSSAVLVAWERPEMHSEQIIGFSLHYQKARGMDNVEYQFAVNNDTTELQVRDLEPNTDYEFYVVAYSQLGASRTSTPALVHTLDDVPSAAPQLSLSSPNPSDIRVAWLPLPPSLSNGQVVKYKIEYGLGKE-DQIFSTEVRGNETQLMLNSLQPNKVYRVRISAGTAAGFGAPSQWMHHRTPSMHNQSHVPFAPAELKVQAKMESLVVSWQPPPHPTQISGYKLYWREVGAEEEANGDRLPGGRGDQAWDVGPVRLKKKVKQYELTQLVPGRLYEVKLVAFNKHEDGYAAVWKGKTEKAPAPDMPIQRGPPLPPAHVHAESNSSTSIWLRWKKPDFTTVKIVNYTVRFSPWGLRNASLVTYYTSSGEDILIGGLKPFTKYEFAVQSHGVDMDGPFGSVVERSTLPDRPSTPPSDLRLSPLTPSTVRLHWCPPTEPNGEIVEYLILYSSNHTQPEHQWTLLTTQGNIFSAEVHGLESDTRYFFKMGARTEVGPGPFSRLQDVITLQEKLSDSLDMHSVTGIIVGVCLGLLCLLACMCAGLRRSPHRESLPGLSSTATPGNPALYSRARLGPPSPPAAHELESLVHPHPQDWSPPPSDVEDRAEVHSLMGGGVSEGRSHSKRKISWAQPSGLSWAGSWAGCELPQ-AGPRPALTRALLPPAGTGQTLLLQALVYDAIKGNGRKKSPPACRNQVEAEVIVHSDFSASNGNPDLHLQDLEPEDPLPPEAPDLISGVGDPGQGAAWLDRELGGCELAAPGPDRLTCLPEAASASCSYPDLQPGEVLEETPGDSCQLKSPCPLGASPGLPRSPVSSSA--", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "***.*:*** **.******:***** *******:***. ***:*:******.**:*:***:****** ********.:**:::********* **.** :.** *.. * **.******.****:***.******** ********* ************ :***************:.**.***.************:****.***********:***** *:** **** :************************:*************************************.*** ********************************:**************************:*:***:* **************************:************ *****.****************.*******:*********:*****************:*******************************************:*****************:*****************.*******:******* *** **:***** ****** ******************.**:*.*****:****. ***************:******************************:****:*** ************************************************************:**:********************************************.**************************************************************************************************.**************:******************************************:.:*****:*:**************************.***:******:.*.******:******** ************:*************:*:*******.**: *.**********..* .************ :*******************************.*****..*****************.**:* ***********:.*..*. :*. * .*** **.*** *: ::.**:************** .****. .:**:**..** *: *** **.***:****: ", "identical_positions": 1084, "similar_positions": 117, "identity": "86.37%" }, { "cls_id": "homologset.agr.MGI:1858500", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O70566-1", "uniprot_id": "DIAP2_MOUSE", "id": "O70566-1", "name": "Protein diaphanous homolog 2", "aln": "------------------------------------------MEELGAAASGAGGGGGGGEEHGGGRSNKRGAGNRAANEEETRNKPKL-----------RDRIT---------------------SFRKSATKREKPVIQHSIDYQTAVVEIPPALIVHDDRSLILS----------EKEVLDLFEKMMED----MNLNEEKKAPLRKKDFSIKREMVVQYISATSKSIVGSKVLGGLKNSK-------------------------HEFTLSSQEYVHELRSG------------------------------------------------------------ISDEKLLNCLESLRVSLTSHPVSWVNNFG-----YEGLGVLLDVLEKLLDKKQQENIDKKNQYKVIQCLKAFMNN-----KFGLQRILGDERS---------------------------------LLLLARAIDPKQQNMMTEIVKILSAICIVGEENILDKLLGGITAAAEL--NNRERFSPIVEG---LENNE----ALHLQVACMQFINALVTSPYDLDFRIHLRNEFLRCGLKAMLPTL----KEIENEGLDIQLRVFEENKEDDL-SELSHRLNDIRAEMDDINEVYHLLYNMLKDTAAEPYLLSILQHFLLIRNDYYIRPQYYKIIEECVSQIVLHCS--GMDPDFKYRQRIDFDFTHLLDACVNKAKVEENEQKAMEFSKKFDEEFTARQEAQAELQKRDE-------------------------------------------------------------------------------------------------------------------KIKELETEIQQLRGQG------------------------VPSAIPGPPPPPPLPG----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------AGPCPPPPPPPPPPPPLPGVVPPPP--------------PPLPGMPGIPPPPPPP-LSGVP-----PPPPPP--------GGVFPLLSGP--------IELPYGMKQKKLYKPDI-PMKRINWSKIEPKELSENCVWLKLKEEKYENADLFAKLALTFPSQMKGQRNTEAAEENRSGPPKKKVKELRILDTKTAQNLSIFLG--------------SYRMPYEEIKNIILEVNEEMLSEALIQNLVKYLPDQNALRELAQLKSEYDDLCEPE-----QFGVVMSTVKMLRPRLTSILFKLTFEEHVNNIKPSIIAVTLACEELKKSESFKRLLELILLVGNYMNSGSRNAQSLGFKINFLCKIKDTKSADQKSTLLHFLAEICDEKYRDILKFPDELEHVESAGKVSAQILKSNLVAMEQSILHLEKNIKNFPPAESH----HDKFVEKMMSFTQNAREQYDKLSTMHSNMLKLYESLGEYFIFDP-NTVNMEEFFGDLNTFRTLFLEALKENHKRKEMEEKSRRAKLAKEKAEQEKLERQKKKKQLIDINKEGDETG-------VMDNLLEALQSGAAF-----RDRRKRIPRNPDNR-RPPLERSRSR---HNGAMSSK--------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8I5ZUN2-1", "uniprot_id": "A0A8I5ZUN2_RAT", "id": "A0A8I5ZUN2-1", "name": "Protein diaphanous homolog 2", "aln": "------------------------------------------MEQPGAAASGAGGGGGG-EEPGVGRSNKRGTGNRAANEEETKNKPKLNIQIKTLADDVRDRIT---------------------SFRKSAIKKEKPLIQHPTDSQAAMGEVPSAQILHDERSLILS----------EKEVLDLFEKMMED----MNLNEEKKAPLRDKDFTTKREMVVQYISATAKSIVGSKVMGGLKNNK-------------------------HEFTLSSQEYVHELRSG------------------------------------------------------------ISDEKLLNCLESLRVSLTSNPVSWVNNFG-----YEGLGVLLDVLEKLLDKKQQENIDKKNQYKIIQCLKAFMNN-----KFGLQRILGDERS---------------------------------LLLLARAIDPKQQNMMTEIVKILSAICIVGEENILDKLLGGITAAAER--NNRERFSPIVEG---LENNE----ALHLQVACMQFINALVTSPYDLDFRIHLRNEFLRCGLKAMLPSL----KEKENDELDIQLRVFEENKEDDL-TELSHRLNDIRAEMDDMNEVFHLLYNMLKDTAAEGYLLSILQHFLLIRNDYYIRPQYYKIIEECVSQIVLHCS--GMDPDFKYRQRIDFDFTHLIDACVNKAKVEESEQKAMEFSKKFDEEFTARQEAQAEIQKRDE-------------------------------------------------------------------------------------------------------------------KIKELESEIQQLQAQG------------------------PGSAFPGPPPPPPLPG----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------AGPCPPPPPPPPP---LPGVGPPPP--------------PPLPGT----APPPPP-LFGAP-----LLPPPP--------GGITPSLPGP--------VELPYGMKQKKLYNPEV-SMKRINWSKIEPRDLSENCVWLKLKEEKYENPDLFAKLALTFPSQMKGQRHGETSEENRIGPQKKKMKELRILDTKTAQNLSIFLG--------------SYRMPYEEIKNIILEVNEELLSEALIQNLVKYLPEQNVLRELAQLKNEYDDLCEPE-----QFGVVMSTVNMLRPRLTSILFKLTFEEHVNNIKPSIIAVTLACEELKKSESFNRLLELILLVGNYMNSGSRNAQSLGFKINFLCKIKDTKSADQKTTLLHFLAEICDEQHRDILKFPEELEHVESASKVSAQILKSNLVAMEQSILHLESNIKNFPKAESL----HDKFVEKMMSFTQNAREQYDKLSTMHSNMLKLYESLGEYFIFDP-NIVTIEEFFGDLNTFRTLFLEALKENHKRKEMEEKSRRAKLAKEKAEQEKLERQKKKKQLIDINKEGDETG-------VMDNLLEALQSGAAF-----RDRRKRIPRNPDNR-RPTLERSRSR---HNGAMPSK--------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O60879-1", "uniprot_id": "DIAP2_HUMAN", "id": "O60879-1", "name": "Protein diaphanous homolog 2", "aln": "------------------------------------------MEQPGAAASGAGG---GSEEPGGGRSNKRSAGNRAANEEETKNKPKLNIQIKTLADDVRDRIT---------------------SFRKSTVKKEKPLIQHPIDSQVAMSEFPAAQPLYDERSLNLS----------EKEVLDLFEKMMED----MNLNEEKKAPLRNKDFTTKREMVVQYISATAKS-------GGLKNSK-------------------------HECTLSSQEYVHELRSG------------------------------------------------------------ISDEKLLNCLESLRVSLTSNPVSWVNNFG-----HEGLGLLLDELEKLLDKKQQENIDKKNQYKLIQCLKAFMNN-----KFGLQRILGDERS---------------------------------LLLLARAIDPKQPNMMTEIVKILSAICIVGEENILDKLLGAITTAAER--NNRERFSPIVEG---LENQE----ALQLQVACMQFINALVTSPYELDFRIHLRNEFLRSGLKTMLPDL----KEKENDELDIQLKVFDENKEDDL-TELSHRLNDIRAEMDDMNEVYHLLYNMLKDTAAENYFLSILQHFLLIRNDYYIRPQYYKIIEECVSQIVLHCS--GMDPDFKYRQRLDIDLTHLIDSCVNKAKVEESEQKAAEFSKKFDEEFTARQEAQAELQKRDE-------------------------------------------------------------------------------------------------------------------KIKELEAEIQQLRTQAQ--------------------VLSSSSGIPGPPAAPPLPG----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------VGPPPPPPAPPLPG---GAPLPPPP--------------PPLPGMMGIPPPPPPPLLFGGP-----PPPPPL--------GGVPPPPGIS--------LNLPYGMKQKKMYKPEV-SMKRINWSKIEPTELSENCFWLRVKEDKFENPDLFAKLALNFATQIKVQKNAEALEEKKTGPTKKKVKELRILDPKTAQNLSIFLG--------------SYRMPYEDIRNVILEVNEDMLSEALIQNLVKHLPEQKILNELAELKNEYDDLCEPE-----QFGVVMSSVKMLQPRLSSILFKLTFEEHINNIKPSIIAVTLACEELKKSESFNRLLELVLLVGNYMNSGSRNAQSLGFKINFLCKIRDTKSADQKTTLLHFIADICEEKYRDILKFPEELEHVESASKVSAQILKSNLASMEQQIVHLERDIKKFPQAENQ----HDKFVEKMTSFTKTAREQYEKLSTMHNNMMKLYENLGEYFIFDS-KTVSIEEFFGDLNNFRTLFLEAVRENNKRREMEEKTRRAKLAKEKAEQEKLERQKKKKQLIDINKEGDETG-------VMDNLLEALQSGAAF-----RDRRKRIPRNPDNR-RVPLERSRSR---HNGAISSK--------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9PZW8-1", "uniprot_id": "A0A8M9PZW8_DANRE", "id": "A0A8M9PZW8-1", "name": "Protein diaphanous homolog 2", "aln": "------------------------------------------MDQQAAGGE---------------DPNK--PSKKKSSEDESKN-KKLNIHIKTLADDMRDRIT---------------------SFRKQGMKKEKPLIQHPTDPISTQTELPVPQPFFDERSMNLS----------EKEIVDLFEKMMED----MNLNEERKAPLRGKDLSTKREMVVQYISATAKSITGSKVAGGLRNSK-------------------------HECTLSSQEYVHELRSG------------------------------------------------------------ISEDKLLNCLESLRVSLTSNPVSWVNNFG-----HEGLGLLLDALERLLDKKQQENIDKKNQHKLIQCLKAFMNN-----KYGLQRILGDERS---------------------------------LLLLARAIDPKQTNMMTEIVKILSAVCIIGEENILDKILAAMTIAAER--NNKERFAPIVEG---LENHE----AQQLQVACMQLINALVTSPDDLDFRIHLRNEFLRCGLKKILPEL----KET--EELDIQLKVFNENKEEDS-IELSHRLDDIRAEMDDMGEVYHLLSNMVKDTGSEPYFLSILQHLLLIRNDYYIRPQYYKVIEECVSQIVLHRS--GMDPDFAYRERLDVDFSHLIDQCVDKAKVDESEQRAAEFSKKFDEEFSARQEAQAELQKQEE-------------------------------------------------------------------------------------------------------------------KIKAFESQINTLQAQLTSERDKLKEAEKSISERNSKIAAGPKAAGAGPPPPPPPPGG---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------IAPPPPPPPPPPPIG--GAPPPPPP--------------PPFPASLGPPPPPPPP-GCGPP-----PPPPPP--------GGGPPPPPGMPSAPPPLVVQLPYGLAPKKTYKPDS-IMKRVNWSKIVPQEMAENCFWLKVKEERFENTDMFSELSLSFSSKSRVKKDVEETDD-RMTQFKKKAKELRILDAKTAQNLSIFLG--------------SFRLPYEEIRDIVLQVDEERLSEALIQNLIKNLPEQKELSNLAELKNEYEELCESE-----QFGIVMSSVKMLRPRLNGILFKLTFEEQVNNIRPDIMNVTFACEEVKKSEGFHMLLEMVLLVGNYMNSGSRNAQTFGFNISFLCKLRDTKSTDQNTTLLHFLAEKCEEKYPEMLKFPDELEHVESASKVAAQTLKASLDIMERHIQRLENDIQNFPKTDDK----QDKFVEKMSGFSKHSREQYEKLSTMHKNMQKLYENLGSYFAFDP-HTVSIEDFFGDLANFRNLFMDAVRENHKKREMEEKIKRAKIAKEKAEREKIERQQKKKQLIDMNKEGDETG-------VMDSLMEALQSGAAF-----RDRRKRTPRNGDQSPSCSAPRWPGA---NHDAASGKSRQPSHWFGKIPFAPQCKPYGPMIACRLRTFAKCQRPKSGDNTEEG----------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P48608-1", "uniprot_id": "DIA_DROME", "id": "P48608-1", "name": "Protein diaphanous", "aln": "----------------------------------------------------------------------------MSRHEKTKSTGGG------LLDSLFGRPS---------------------KSKGGTISSG--TLAHGGRPVSADNYVVPGVEDFEQYIQQLS----------VAELDAKFLEIIED----MNIPKDKREPLLAKSKEERQKMIMWHLKG----------KNSLERSA-------------------------NSRFEKPIDYVEYLQNGE-----------------------------------------------------------HSTHKVYQCVESLRVALTSNPISWIKEFG-----VAGIG----TIEKLLARSKNNASYEKIEFEAIRCLKAIMNN-----TWGLNVVLNPDQHS-------------------------------VVLLLAQSLDPRKPQTMCEALKLLASFCIVYERNGYEKVLRAITTIAATSFKASERFRPIVDA---LFASDQQDPKRDLACHSLIFINTLTNTPTDLNFRLHLRCEIMRMGLYDRLDEFTKIVEASNNENLQQHFKIFNEIREDDF-EEFVQRFDNVTFNMDDATDCFDVLKNLVTDTTSEPYFLSILQHLLYIRDDFYFRPAYYQLIEECISQIVFHKG--YCDPNFENRN-FNIDTSLLLDDIVEKAKAKES-KRSEEYEKKIEQLESAKQEAEAKAAHLEE-------------------------------------------------------------------------------------------------------------------KVKLMEANGVAAPSPN-------------------------KLPKVNIPMPPPPPG----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------GGGAPPPPPPPMPGRAGGGPPPPPP--------------PPMPGRAGGPPPPPPPPGMGGP-----PPPPMPGMMRP---GGGPPPPPMMMG---PMVPVLPHGLKPKKKWDVKN-PMKRANWKAIVPAKMSDKAFWVKCQEDKLAQDDFLAELAVKFSSKPVKKEQKDAVDK--PTTLTKKNVDLRVLDSKTAQNLAIMLGG------------SLKHLSYEQIKICLLRCDTDILSSNILQQLIQYLPPPEHLKRLQEIKAKGEPLPPIE-----QFAATIGEIKRLSPRLHNLNFKLTYADMVQDIKPDIVAGTAACEEIRNSKKFSKILELILLLGNYMNSGSKNEAAFGFEISYLTKLSNTKDADNKQTLLHYLADLVEKKFPDALNFYDDLSHVNKASRVNMDAIQKAMRQMNSAVKNLETDLQNNKVPQCD----DDKFSEVMGKFAEECRQQVDVLGKMQLQMEKLYKDLSEYYAFDP-SKYTMEEFFADIKTFKDAFQAAHNDNVRVREELEKKRRLQEAREQSAREQQERQQRKKAVVDMDAPQTQEG-------VMDSLLEALQTGSAFGQ---RNRQARRQRPAGAERRAQLSRSRSRTRVTNGQLMTREMILNEVLGSA---------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P41832-1", "uniprot_id": "BNI1_YEAST", "id": "P41832-1", "name": "Protein BNI1", "aln": "MLKNSGSKHSNSKESHSNSSSGIFQNLKRLANSNATNSNTGSPTYASQQQHSPVGNEVSTSPASSSSFRKLNAPSRSTSTEARPLNKKSTLNTQNLSQYMNGKLSGDVPVSSQHARSHSMQSKYSYSKRNSSQASNKLTRQHTGQSHSASSLLSQGSLTNLSKFTTPDGKIYLEMPSDPYEVEVLFEDIMYKRNIFQSLSEDKQEALMGYSIEKKWLIVKQDLQNELKKMRANTTSSSTASRTSMASDHHPILTANSSLSSPKSVLMTSASSPTSTVYSNSLNHSTTLSSVGTSTSKGKKLVSGSLKKQPSLNNIYRGGAENNTSASTLPGDRTNRPPIHYVQRILADKLTSDEMKDLWVTLRTEQLDWVDAFIDHQGHIAMANVLMNSIYKTAPRENLTKELLEKENSFFKCFRVLSMLSQGLYEFSTHRLMTDTVAEGLFSTKLATRKMATEIFVCMLEKKNKSRFEAVLTSLDKKFRIGQNLHMIQNFKKMPQYFSHLTLESHLKIIQAWLFAVEQTLDGRGKMGSLVGASDEFKNGGGENAILEYCQWTMVFINHLCSCSDNINQRMLLRTKLENCGILRIMNKI----KLLDYDKVIDQIELYDNNKLDDFNVKLEANNKAFNVDLHDPLSLLKNLWDICKGTENEKLLVSLVQHLFLSSSKLIEENQNSSKLTKQLKLMDSLVTNVSVASTSDEETNMNMAIQRLYDAMQTDEVARRAILESRALTKKLEEIQAERDSLSEKLSKAEHGLVGQLEDELHERDRILAKNQRVMQQLEAELEELKKKHLLEKHQQEVELRKMLTILNSRPEESFNKNEGTRGMNSSLNSSEKANIQKVLQDGLSRAKKDYKDDSKKFGMTLQPNKRLKMLRMQMENIENEARQLEMTNFAEFEKDRLEPPIHIKKPKVKKMKNKDRKPLVKPQEADVNKLNDLRRALAEIQMESNDISKFNVEERVNELFNEKKSLALKRLKELETKYKGFGIDFNVDEIMDSPKKNTGDVETEEDANYASLDPKTYQKKLDEINRITDQLLDIQTQTEHEIQVEEDGESDLSSSSSDDESEEIYQDASPTQELRSEHSELSSGSGPGSFLDALSQKYGTGQNVTASAAFGENNNGSGIGPLHSKVEKTFMNRLRKSTVSSAPYLEELTQKVNKVEPYEQNEDEGLDKKSLPENSTASAASAFDKAEKDMRQHVENGKQGRVVNHEEDKTADFSAVSKLNNTDGAEDLSTQSSVLSSQPPPPPPPPPPVPAKLFGESLEKEKKSEDDTVKQETTGDSPAPPPPPPPPPPPPMALFGKPKGETPPPPPLPSVLSSSTDGVIPPAPPMMPASQIKSAVTSPLLPQSPSLFEKYPRPHKKLKQLHWEKLDCTDNSIWGTGKAEKFAD-DLYEKGVLADLEKAFAAREIKSLASKRKEDLQKITFLSRDISQQFGINLHMYSSLSVADLVKKILNCDRDFLQTPSVVEFLSKSEIIEVSVNLARNYAPYSTDWEGVRNLEDAKPPEKDPNDLQRADQIYLQLMVNLESYWGSRMRALTVVTSYEREYNELLAKLRKVDKAVSALQESDNLRNVFNVILAVGNFMN--DTSKQAQGFKLSTLQRLTFIKDTTNSMTFLNYVEKIVRLNYPSFNDFLSELEPVLDVVKVSIEQLVNDCKDFSQSIVNVERSVEIGNLSDSSKFHPLDKVLIKTLPVLPEARKKGDLLEDEVKLTIMEFESLMHTYGEDSGDKFAKISFFKKFADFINEYKKAQAQNLAAEEEERLYIKHKKIVEEQQKRAQEKEKQKENSNSPSSEGNEEDEAEDRRAVMDKLLEQLKNAGPAKSDPSSARKRALVRKKYLSEKDNAPQLLNDLDTEEGSILYSPEAMDPTADTVIHAESPTPLATRGVMNTSEDLPSPSKTSALEDQEEISDRARMLLKELRGSDTPVKQNSILDEHLEKLRARKERSIGEASTGNRLSFK", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : .: : . : * : . . . *: * .:: . .: :::: .* . : :: :. .. .. * . *. . : . : ::.* *:* :. :.*:. * . : : :.: : : . ::*::.: :. : :: : * : : : * : .* :. : *:: . . . :: .:* . : . : :** * . . ::: *: ** :: . *: : : : : : ::.:::: : :* :: . . . ::.* . . * :: ..* * ::*::**:: .. . . : : :. : . . ::. * * . . . .: **::: : ::. . : : :. ::* :. : * ****.** * .* * .**** * * ** * * * . :. *: : . :::..* : :: : *: : : : .. . . * * :. : . ** : . : .: : . : :* : :: . : : .* : * . : : :. . .*: : . :: ::: ..: * . :::*. : :::::* :**:** . . : **::. * :: *.: :. *:*::: . :. . .* .:*. * .. :* : : :. : .:* .:: .: **. . .*:: : * ::.* : *. .** .: * : * :* .* . : : *: :. *::::*: . . : . ***.*:* *:.... *: * : . .. ", "identical_positions": 110, "similar_positions": 333, "identity": "5.61%" }, { "cls_id": "homologset.agr.MGI:1858510", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q61220-1", "uniprot_id": "NELL2_MOUSE", "id": "Q61220-1", "name": "Protein kinase C-binding protein NELL2", "aln": "MHAMESRVLLRTFCVILGLGAVWGLGVDPSLQIDVLTELELGESTDGVRQVPGLHNGTKAFLFQESPRSIKASTATAERFFQKLRNKHEFTILVTLKQIHLNSGVILSIHHLDHRYLELESSGHRNEIRLHYRSGTHRPHTEVFPYILADAKWHKLSLAFSASHLILHIDCNKIYERVVEMPSTDLPLGTTFWLGQRNNAHGYFKGIMQDVHVLVMPQGFIAQCPDLNRTCPTCNDFHGLVQKIMELQDILSKTSAKLSRAEQRMNRLDQCYCERTCTVKGTTYRESESWTDGCKNCTCLNGTIQCETLVCPAPDCPPKSAPAYVDGKCCKECKSTCQFQGRSYFEGERNTVYSSSGMCVLYECKDQTMKLVE-NIGCPPLDCPESHQIALSHSCCKVCKGYDFCSEKH--TCMENSVCRNLNDRAVCSCRDGFRALREDNAYCEDIDECAEGRHYCRENTMCVNTPGSFMCICKTGYIRIDDYSCTEHDECLTNQHNCDENALCFNTVGGHNCVCKPGYTGNGTTCKAFCKDGCRNGGACIAANVCACPQGFTGPSCETDIDECSEGFVQCDSRANCINLPGWYHCECRDGYHDNGMFAPGGESCEDIDECGTGRHSCTNDTICFNLDGGYDCRCPHGKNCTGDCVHEGKVKHTGQIWVLENDRCSVCSCQTGFVMCRRMVCDCENPTVDLSCCPECDPRLSSQCLHQNGETVYNSGDTWVQDCRQCRCLQGEVDCWPLACPEV-ECEFSVLPENECCPRCVTDPCQADTIRNDITKTCLDEMNVVRFTGSSWIKHGTECTLCQCKNGHLCCSVDPQCLQEL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q62918-1", "uniprot_id": "NELL2_RAT", "id": "Q62918-1", "name": "Protein kinase C-binding protein NELL2", "aln": "MHAMESRVLLRTFCVILGLEAVWGLGVDPSLQIDVLSELELGESTAGVRQVPGLHNGTKAFLFQDSPRSIKAPIATAERFFQKLRNKHEFTILVTLKQIHLNSGVILSIHHLDHRYLELESSGHRNEIRLHYRSGTHRPHTEVFPYILADAKWHKLSLAFSASHLILHIDCNKIYERVVEMPSTDLPLGTTFWLGQRNNAHGYFKGIMQDVQLLVMPQGFIAQCPDLNRTCPTCNDFHGLVQKIMELQDILSKTSAKLSRAEQRMNRLDQCYCERTCTMKGTTYREFESWTDGCKNCTCLNGTIQCETLVCPAPDCPAKSAPAYVDGKCCKECKSTCQFQGRSYFEGERSTVFSASGMCVLYECKDQTMKLVE-NAGCPALDCPESHQIALSHSCCKVCKGYDFCSEKH--TCMENSVCRNLNDRAVCSCRDGFRALREDNAYCEDIDECAEGRHYCRENTMCVNTPGSFLCICQTGYIRIDDYSCTEHDECLTNQHNCDENALCFNTVGGHNCVCKPGYTGNGTTCKAFCKDGCRNGGACIAANVCACPQGFTGPSCETDIDECSEGFVQCDSRANCINLPGWYHCECRDGYHDNGMFAPGGESCEDIDECGTGRHSCANDTICFNLDGGYDCRCPHGKNCTGDCVHDGKVKHNGQIWVLENDRCSVCSCQTGFVMCRRMVCDCENPTVDLSCCPECDPRLSSQCLHQNGETVYNSGDTWVQDCRQCRCLQGEVDCWPLACPEV-ECEFSVLPENECCPRCVTDPCQADTIRNDITKTCLDEMNVVRFTGSSWIKHGTECTLCQCKNGHVCCSVDPQCLQEL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q99435-1", "uniprot_id": "NELL2_HUMAN", "id": "Q99435-1", "name": "Protein kinase C-binding protein NELL2", "aln": "---MESRVLLRTFCLIFGLGAVWGLGVDPSLQIDVLTELELGESTTGVRQVPGLHNGTKAFLFQDTPRSIKASTATAEQFFQKLRNKHEFTILVTLKQTHLNSGVILSIHHLDHRYLELESSGHRNEVRLHYRSGSHRPHTEVFPYILADDKWHKLSLAISASHLILHIDCNKIYERVVEKPSTDLPLGTTFWLGQRNNAHGYFKGIMQDVQLLVMPQGFIAQCPDLNRTCPTCNDFHGLVQKIMELQDILAKTSAKLSRAEQRMNRLDQCYCERTCTMKGTTYREFESWIDGCKNCTCLNGTIQCETLICPNPDCPLKSALAYVDGKCCKECKSICQFQGRTYFEGERNTVYSSSGVCVLYECKDQTMKLVE-SSGCPALDCPESHQITLSHSCCKVCKGYDFCSERH--NCMENSICRNLNDRAVCSCRDGFRALREDNAYCEDIDECAEGRHYCRENTMCVNTPGSFMCICKTGYIRIDDYSCTEHDECITNQHNCDENALCFNTVGGHNCVCKPGYTGNGTTCKAFCKDGCRNGGACIAANVCACPQGFTGPSCETDIDECSDGFVQCDSRANCINLPGWYHCECRDGYHDNGMFSPSGESCEDIDECGTGRHSCANDTICFNLDGGYDCRCPHGKNCTGDCIHDGKVKHNGQIWVLENDRCSVCSCQNGFVMCRRMVCDCENPTVDLFCCPECDPRLSSQCLHQNGETLYNSGDTWVQNCQQCRCLQGEVDCWPLPCPDV-ECEFSILPENECCPRCVTDPCQADTIRNDITKTCLDEMNVVRFTGSSWIKHGTECTLCQCKNGHICCSVDPQCLQEL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F1QV50-1", "uniprot_id": "F1QV50_DANRE", "id": "F1QV50-1", "name": "NEL-like protein 2", "aln": "---MGLFKLYFALCTVG-LFYVSGLGVDPALHVDIFQEIDLEKSSAGVSQVQGFHNDSRAYQFEGSSRNARASLKAAERILQKLRGRTEFTLLLTLKQEKFSSGVLLSIHYGEQRFLEVESSGLRNEIRLFFQTPDQRQQREVFPYSLADGHWHKISLAFSATQVVLHIDCNRIYERIVETPSMEFPRGTNIWVGQRNDAHGFFRGVMQDVQLVVVPHGYVVQCPDLNRTCPTCNDFHGLVQKIMELQDILAKTSNKLALAEEKMKYLDGCYCERTCTLNGEIFRDSDAWIDGCRNCTCSNGTVECESIFCPPPQCPPDTAPIYMPGACCKECQPVCLFRGRVYVEGDRKSIHDSEGNCLLFECRDRSMRRVE-MTSCPDLNCPESEQITLTDRCCKVCRGHDFCTEGYSRNCVENSDCINLEAGACCSCKEGYHALRDDSAYCQDIDECAEGKHYCRENTVCMNTPGSFMCVCHTGFVRIDDYSCTEHDECVRGLNTCDENALCFNTVGGHSCSCKPGYIGNGTFCRALCEGQCLNGGSCVAPDTCVCQQGFTGKRCETDIDECSDGFVECDSRATCVNLPGWYHCECRDGYHDNGMFSANGESCEDIDECEMGRHSCANDTICFNVDGGYDCRCPHGRNCTGDCAHDGKVKHNGQIWVLDDDRCSVCSCQSGLVMCRRMVCDCENPTVDVLCCPECDPRLSSQCLHQNGLLAYSNGETWVENCQQCQCMRGEVDCWPVSCAPVSDCEFTVVPDGECCPRCVTDPCLADTVRNDITKTCVDEYGISRFSGSAWTKHGTECSLCQCKNGHICCSVDPLCL---", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A1A5Y0-1", "uniprot_id": "NELL2_DANRE", "id": "A1A5Y0-1", "name": "Protein kinase C-binding protein NELL2a", "aln": "---MAFLQLFVGLLCG---AAVSAFGVDPAVRIGVFQEFSPGQGFSGVTQVKGFRDDTRAFMFQGSSRSVRVPDAAAGHMLQKLRGKTEFSIALTLKQDKLNSGVILSIHHGEHRLLELESSGQKSEVRLHFRTGLQQTHTEIFPFTLADEQWHRVSVSISAAHLTLYVDCNRIYERVVPVPLMEIPEDSSFWVGQRNSAHGLFKGIMQDLQILVMPQGFITQCPDLNRTCPTCNDFHGLVQKIMELQDILAKTSSKLSLAEEKMSGLDSCYCERTCRVKDQIYREEQSWTDGCKNCTCSNGTVRCEKILCPPLDCPDGTTPAYVTGTCCKECQPMCLFSEQTLVEGQSCAVHHPSGLCQLFQCRDRTMHRVPGAEDCPALSCAESDQITLTDRCCRVCRGHDFCAEEN--ICSENSDCVNLDAGASCGCKNGFRPLRLDSAYCEDIDECAEGRHYCRENTECVNTAGSFMCVCHTGFIRIDDYSCTEHDECASGQHDCDENALCFNTVGGHSCSCKPGYSGNGTVCRALCDGRCLNGGSCASPNVCVCVQGFSGQNCETDIDECSEGLVQCAAHATCVNLPGWYHCECRDGYHDNEVFSANGESCRDIDECRTGRSTCANDTVCFNLDGGFDCRCPHGHNCSGDCIHNSRVRHNAQIWVLDTDHCSVCSCQEGQVKCRRMVCDCENPTVDVLCCPECDPRLTSQCLHQNGLLTYSSGDTWIDSCQRCQCLQGEVDCWPLSCPPV-DCDFTLVPEGECCPRCVSDPCQAHAVRSDISKTCIDEHGITRFSGSAWVKHGTHCTLCQCKNGHVCCSVDPMCL---", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * * : * .:****::::.:: *:. :. ** ** *:::.::*: *: :.*. :.. :* :::****.: **:: :**** ::.***:****: ::* **:**** :.*:**.::: :: : *:**: *** :**::*:::**::: *::***:****:* * ::* .:.:*:****.*** *:*:***::::*:*:*::.*****************************:*** **: **::*. ** ******* ::. :*: ::* ***:**** ***:.**.:.** :** :: *: * *****:. * * : .**: ::. ..* * *::*:*::*: * .** *.*.**.**:*:. **:**:*:***:* * *** * **: * *.*::*::.** *.***:********:******* *:**.***:*:*:**::************* . : **************.* ***** **** *:*:*.. * ***:* :.:.*.* ***:* *********:*:*:* ::*.*:***************** :*:..****.***** ** :*:***:***:***:*******:**:*** *:.:*:*..*****: *:******* * * **************: *********:******** *..*:**::.*::*:*::*******:.*. * :*:*:::*:.*******:*** *.::*.**:***:** .: **:**:* ****.*:********:****** ** ", "identical_positions": 453, "similar_positions": 233, "identity": "55.04%" }, { "cls_id": "homologset.agr.MGI:1858598", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P70709-1", "uniprot_id": "ECP_RAT", "id": "P70709-1", "name": "Eosinophil cationic protein", "aln": "MGLKLLESRLCLLLSLGLVLMLASCQPPTP----SQWFEIQHIYNRAYPRCNDAMRHRNRFTGHCKDINTFLHTSFASVVGVCGNRNIPCG-NRTYRNCHNSRYRVSITFCNLTTP-ARIYTQCRYQTTRSRKFYTVGCDPRTPR-DSPMYPVVPVHLDRIF", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O35292-1", "uniprot_id": "RNS2B_MOUSE", "id": "O35292-1", "name": "Ribonuclease 2B", "aln": "MGLKLLESRLCLLLLLGLVLTLVSCQRPTP----SQKFDIQHIYKKSSPKCDDAMRVVNKYTGKCKDLNTFLHTTFADVVRVCHNPPKTCK-DGTSPNCHDSSSKVSVTICKLTKR-ARNYTHCRYKTTGAKKSYTVACNPRTPK-DRPTYPVVPVHLDRLF", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P10153-1", "uniprot_id": "RNAS2_HUMAN", "id": "P10153-1", "name": "Non-secretory ribonuclease", "aln": "MVPKLFTSQICLLLLLGLLAVEGSLHVKPPQFTWAQWFETQHINMTS-QQCTNAMQVINNYQRRCKNQNTFLLTTFANVVNVCGNPNMTCPSNKTRKNCHHSGSQVPLIHCNLTTPSPQNISNCRYAQTPANMFYIVACDNRDQRRDPPQYPVVPVHLDRII", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P12724-1", "uniprot_id": "ECP_HUMAN", "id": "P12724-1", "name": "Eosinophil cationic protein", "aln": "MVPKLFTSQICLLLLLGLMGVEGSLHARPPQFTRAQWFAIQHISLNP-PRCTIAMRAINNYRWRCKNQNTFLRTTFANVVNVCGNQSIRCPHNRTLNNCHRSRFRVPLLHCDLINPGAQNISNCTYADRPGRRFYVVACDNRDPR-DSPRYPVVPVHLDTTI", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* **: *::**** ***: * : .* :* * *** . :* **: *.: :**: **** *:**.** ** * * : * *** * :*.: *.* . .: ::* * .. * *.*: * : * * ********* :", "identical_positions": 62, "similar_positions": 32, "identity": "38.27%" }, { "cls_id": "homologset.agr.MGI:1858599", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0ABK0LS36-1", "uniprot_id": "A0ABK0LS36_RAT", "id": "A0ABK0LS36-1", "name": "", "aln": "-MQPPWGLALPLLLPWVAGGVG--TSPRDYWLPALAHQPGVCHYGTKTACCYGWKRNSKGVCE-------------------------------DVNECAFKPRPCQHRCVNTHGSYKCFCLSGHMLLPDATCSNSRTCARINCQYSCEDTAEGPRCVCPSSGLRLGPNGRVCLDIDECASSKAVCPSNRRCVNTFGSYYCKCHIGFELKYISRRYDCVDINECTLNTRTCSPHANCLNTQGSFKCKCKQGYRGNGLQCSVIPEHSVKEILTAPGTIKDRIKKLLAHKHTMKKKVKLKNVTPRPTSTRAPKVNLP-YSSEEGVSRGRNSGGEQKRKEERKRKRLEEEK-SEKALRNEVEQERPLRGDVFSPKVNEAEDLDLVYIQRKELNSKQEHKADLNISVDCSFDLGVCDWKQDREDDFDWNPADRDNDVGYYMAVPALAGHKKNIGRLKLLLPNLTPQSNFCLLFDYRLAGDKVGKLRVFVKNSNNALAWEETKTEDGKWKTGKVPLYQGIDTTKSVIFEAERGKGKTGEIAVDGVLLVSGLCPDDFLSEEG", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9JJZ5-1", "uniprot_id": "EGFL6_MOUSE", "id": "Q9JJZ5-1", "name": "Epidermal growth factor-like protein 6", "aln": "-MQPPWGLALPLLLPWVTGGVG--TSPWDYGLSALAHQPGVCQYGTKMACCYGWKRNNKGVCEAMCEPRCKFGECVGPNKCRCFPGYTGKTCTQDVNECGVKPRPCQHRCVNTHGSYKCFCLSGHMLLPDATCSNSRTCARLNCQYGCEDTEEGPRCVCPSSGLRLGPNGRVCLDIDECASSKAVCPSNRRCVNTFGSYYCKCHIGFELKYIGRRYDCVDINECALNTHPCSPHANCLNTRGSFKCKCKQGYRGNGLQCSVIPEHSVKEILTAPGTIKDRIKKLLAHKRTMKKKVKLKMVTPRPASTRVPKVNLP-YSSEEGVSRGRNYDGEQKKKEEGKRERLEEEK-GEKTLRNEVEQERTLRGDVFSPKVNEAEDLDLVYVQRKELNSKLKHK-DLNISVDCSFDLGVCDWKQDREDDFDWHPADRDNDVGYYMAVPALAGHKKNIGRLKLLLPNLTPQSNFCLLFDYRLAGDKVGKLRVFVKNSNNALAWEETKNEDGRWRTGKIQLYQGIDTTKSVIFEAERGKGKTGEIAVDGVLLVSGLCPDDFLSVEG", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8IUX8-1", "uniprot_id": "EGFL6_HUMAN", "id": "Q8IUX8-1", "name": "Epidermal growth factor-like protein 6", "aln": "-MPLPWSLALPLLLSWVAGGFGNAASARHHGLLASARQPGVCHYGTKLACCYGWRRNSKGVCEATCEPGCKFGECVGPNKCRCFPGYTGKTCSQDVNECGMKPRPCQHRCVNTHGSYKCFCLSGHMLMPDATCVNSRTCAMINCQYSCEDTEEGPQCLCPSSGLRLAPNGRDCLDIDECASGKVICPYNRRCVNTFGSYYCKCHIGFELQYISGRYDCIDINECTMDSHTCSHHANCFNTQGSFKCKCKQGYKGNGLRCSAIPENSVKEVLRAPGTIKDRIKKLLAHKNSMKKKAKIKNVTPEPTRTPTPKVNLQPFNYEEIVSRGGNSHGGKKGNEEKMKEGLEDEKREEKALKNDIE-ERSLRGDVFFPKVNEAGEFGLILVQRKALTSKLEHK-DLNISVDCSFNHGICDWKQDREDDFDWNPADRDNAIGFYMAVPALAGHKKDIGRLKLLLPDLQPQSNFCLLFDYRLAGDKVGKLRVFVKNSNNALAWEKTTSEDEKWKTGKIQLYQGTDATKSIIFEAERGKGKTGEIAVDGVLLVSGLCPDSLLSVDD", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AB40E9Z3-1", "uniprot_id": "A0AB40E9Z3_DANRE", "id": "A0AB40E9Z3-1", "name": "", "aln": "MKHLTWISALSLLLSFTLGTAD----HRQRRQISVMSGLGVCRYGSRLECCYGWKKNTKGQCEAQCDLGCKHGECVGPNKCKCFPGYTGKTCSQDLNECGLKPRPCEHRCMNTFGSYMCYCLNGYMLMPDGSCANSRTCSLAHCQYGCEEVQSEVRCLCPSPGLQLGSDGKTCEDIDECATGKNQCPFNRQCTNTFGSYYCKCQPGYDLKYINGKYDCVDVNECTSNTHKCSHHAECINTLGSYKCKCKQGFRGSGFDCSVKP-FYHRSWDSSKGNTDVLVNAIPDFPSKTRILGKFENSIPEPVLTESPRQHLQPFDYDGEVYIGAPQETPVFPEEEEVEE--EEEEDTENQLE---DEELTSRGDVFS-----QDDFVSFYQSELELKEIQAAPLKERFLTDCDFDRGACEWVQDNADDLDWTIKYHPDGREYYLALEGPVGNRREQARMKLLLEDHMRQSSFCLRFDFRIEGPQTGVLRVKLDNS-AISIWERKQSQKQSWQSEQISISWTDSNPEAVVFEAERGRSGTGEIALDHVLLISGECSEDKTLDF-", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .* **.***.:. * . . : ***:**:: *****::*.** ** *:***..*****:***:**.*** *:**.*:**:**.:* *****: :***.**:. . :*:***.**:*..:*: * ******:.* ** **:*.**********: *::*:**. :***:*:***: ::: ** **:*:** **:*******::*.*: **. * :. : *. . :: : . . : *:: *.*. * *: :* :. : * * :** .: *:*: *: *. : * . ***** :: . .. *.. . .: .**.*: * *:* **. **:** : : :*:*: . .*:::: .*:**** : **.*** **:*: * :.* *** :.** **.. .:. *:: :: : . .::::******:. *****:* ***:** *.:. ", "identical_positions": 199, "similar_positions": 153, "identity": "35.79%" }, { "cls_id": "homologset.agr.MGI:1858600", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O43374-1", "uniprot_id": "RASL2_HUMAN", "id": "O43374-1", "name": "Ras GTPase-activating protein 4", "aln": "------------------------------------------------------------------MAKRSSLYIRIVEGKNLPAKDITGSSDPYCIVKVDNEPIIRTATVWKTLCPFWGEEYQVHLPPTFHAVAFYVMDEDALSRDDVIGKVCLTRDTIASHPKGFSGWAHLTEVDPDEEVQGEIHLRLEVWPGARACRLRCSVLEARDLAPKDRNGTSDPFVRVRYKGRTRETSIVKKSCYPRWNETFEFELQEGAMEALCVEAWDWDLVSRNDFLGKVVIDVQRLRVVQQEEGWFRLQPDQSKSRRHDEGNLGSLQLEVRLRDETVLPSSYYQPLVHLLCHEVKLGMQGPGQLIPLIEETTSTECRQDVATNLLKLFLGQGLAKDFLDLLFQLELSRTSETNTLFRSNSLASKSMESFLKVAGMQYLHGVLGPIINKVFEEKKYVELDPSKVEVKDVGCSGLHRPQTEAEVLEQSAQTLRAHLGALLSALSRSVRACPAVVRATFRQLFRRVRERFPGAQHENVPFIAVTSFLCLRFFSPAIMSPKLFHLRERHADARTSRTLLLLAKAVQNVGNMDTPASRAKEAWMEPLQPTVRQGVAQLKDFITKLVDIEEKDELDLQRTLSLQAPPVKEGPLFIHRTKGKGPLMSSSFKKLYFSLTTEALSFAKTPSSKKSALIKLANIRAAEKVEEKSFGGSHVMQVIYTDDAGRPQTAYLQCKCVNELNQWLSALRKVSINNTGLLGSYHPGVFRGDKWSCCHQKEKTGQGCDKTRSRVTLQEWNDPLDHDLEAQLIYRHLLGVEAMLWERHREL-SGGAEAGTVPTSPGKVPEDSLARLLRVLQDLREAHSSSPAGSPPSEPNCLLELQT", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "C9J798-1", "uniprot_id": "RAS4B_HUMAN", "id": "C9J798-1", "name": "Ras GTPase-activating protein 4B", "aln": "------------------------------------------------------------------MAKRSSLYIRIVEGKNLPAKDITGSSDPYCIVKVDNEPIIRTATVWKTLCPFWGEEYQVHLPPTFHAVAFYVMDEDALSRDDVIGKVCLTRDTIASHPKGFSGWAHLTEVDPDEEVQGEIHLRLEVWPGARACRLRCSVLEARDLAPKDRNGTSDPFVRVRYKGRTRETSIVKKSCYPRWNETFEFELQEGAMEALCVEAWDWDLVSRNDFLGKVVIDVQRLRVVQQEEGWFRLQPDQSKSRRHDEGNLGSLQLEVRLRDETVLPSSYYQPLVHLLCHEVKLGMQGPGQLIPLIEETTSTECRQDVATNLLKLFLGQGLAKDFLDLLFQLELSRTSETNTLFRSNSLASKSVESFLKVAGMQYLHGVLGPIINKVFEEKKYVELDPSKVEVKDVGCSGLHRPQTEAEVLEQSAQTLRAHLGALLSALSRSVRACPAVVRATFRQLFRRVRERFPGAQHENVPFIAVTSFLCLRFFSPAIMSPKLFHLRERHADARTSRTLLLLAKAVQNVGNMDTPASRAKEAWMEPLQPTVHQGVAQLKDFITKLVDIEEKDELDLQRTLSLQAPPVKEGPLFIHRTKGKGPLMSSSFKKLYFSLTTEALSFAKTPSSKKSALIKLANIRAAEKVEEKSFGGSHVMQVIYTDDAGRPQTAYLQCKCVNELNQWLSALRKVSINNTGLLGSYHPGVFRGDKWSCCHQKEKTGQGCDKTRSRVTLQEWNDPLDHDLEAQLIYRHLLGVEAMLWERHREL-SGGAEAGTVPTSPGKVPEDSLARLLRVLQDLREAHSSSPAGSPPSEPNCLLELQT", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "D3ZQH9-1", "uniprot_id": "D3ZQH9_RAT", "id": "D3ZQH9-1", "name": "", "aln": "MQCLPALARGAGRGEWSSGDPSAPALPSLASAPACLQRHSHCPLPLSGGDPGVRTAPYRPPRRRPAMAKRSSLSIRIVEGKNLPAKDITGSSDPYCIVKVDNEPIIRTATVWKTLCPFWGEEYQVHLPPTFHMVAFYVMDEDALSRDDVIGKVCLTRDELTSHPKGFIGWTHLVEVDPNEEVQGEIHLRLEVVPGLHASRLRCSVLEARDLAPKDRNGASDPFVRVHYNGRTQETSVVKKSCYPRWNETFEFELEKGATEALLVEAWDWDLVSRNDFLGKVVVNVQTLCSAQQEEGWFRLQPDQSKSR-QGKGNLGSLQLEVRLRDETVLPSVYYQPLVQLLCQEVKLGTQGPGQLIPVIEETTSAECRQEVATTLLKLFLGQGLAKDLLDLLFQLELGRTSEANTLFRSNSLASKSMESFLKVAGMRYLHGILGPIIDRVFEEKKYVELDPSKVEVKDVGCSGLHRPQTEAEVLEQSAQTLRAHLVALLSAICRSVRTCPAVVRATFRQLFRRVRERFPSAQHQNVPFIAVTSFLCLRFFSPAILSPKLFHLRERHADARTSRTLLLLAKAVQNIGNMDTPVSRAKESWMEPLQPTVRQGVVQLKDFITKLVDIEEKEELDLQRALNLQAPPVKEGPLFIHRTKGKGPLASSSFKKLYFSLTTEALSFAKTSSSKKSVFIKLASIRAAEKVEEKSFGSSHVMQVIYSDDVGRAQTVYLQCKCVNELNQWLSALRKVITNNASLLGSYHPGVFRGDKWSCCHQKEKTDLGCDKTHSRVTLQEWNDPLDHDLEAQLIYRHLLGVEAALREKHQLLSRATEEAGTSSTGRGGAPEDSLAQLLRVLRDLREAHSSSLASSPSREPRHLLELQT", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q6PFQ7-1", "uniprot_id": "RASL2_MOUSE", "id": "Q6PFQ7-1", "name": "Ras GTPase-activating protein 4", "aln": "------------------------------------------------------------------MAKRSSLSIRIVEGKNLPAKDITGSSDPYCIVKVDNEPIIRTATVWKTLCPFWGEDYQVHLPPTFHTVAFYVMDEDALSRDDVIGKVCLTRDALASHPKGFSGWTHLVEVDPNEEVQGEIHLRLEVVPGVHASRLRCAVLEARDLAPKDRNGASDPFVRVHYNGRTQETSVVKKSCYPRWNETFDFELEKGASEALLVEAWDWDLVSRNDFLGKVAVNVQRLCSAQQEEGWFRLQPDQSKSR-QGKGNLGSLQLEVRLRDETVLPSVCYQPLVQLLCQEVKLGTQGPGRLIPVIEETTSAECRQEVATTLLKLFLGQGLAKDFLDLLFQLELGRTSEANTLFRSNSLASKSMESFLKVAGMRYLHGILGPIIDRVFEEKKYVELDPSKVEVKDVGCSGLHRPQTEAEVLEQSAQTLRAHLVALLSAICRSVRTCPAIIRATFRQLFRRVRERFPNAQHQNVPFIAVTSFLCLRFFSPAILSPKLFHLRERHADARTSRTLLLLAKAVQNIGNMDTPVSRAKESWMEPLQPTVRQGVAQLKDFIMKLVDIEEKEELDLQRALNSQAPPVKEGPLFIHRTKGKGPLASSSFKKLYFSLTTEALSFAKTSSSKKSTFIKLASIRAAEKVEEKSFGSSHIMQVIYADDVGRAQTVYLQCKCVNELNQWLSALRKASTNNRGLLRSYHPGIFRGDKWSCCHQKDKTDQGCDKTHSRVTLQEWNDPLDHDLEAQLIYRHLLGVEAALRERYQLL-RGATEAGVSPTGCDGAPEDSLAQLLRVLQDLREAHGSSLASPAAREPHHLLELQT", "tax_id": 10090, "tax_name": "Mouse" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ******* ***********************************************:********** ************************* ::****** **:**.****:************* ** :*.****:**************:*******:*:***:***:*************:***::** *** ******************.::** * .***************** :.:******************** *****:***:***** ****:***:******:****:***.*************:*********.****:*************:*********:****:*****::********************************************** *****:.****:***::****************.***:********************:*****************************:******.*****:*********:***.****** ********:******:*. ********************* *********************.*****.:****.*************.**:*****:**.**.**.*******************. ** .** *****:************:**. *****:****************************** * *::: * . ***. .*. . .******:*****:******.** *.... **. ******", "identical_positions": 679, "similar_positions": 88, "identity": "78.05%" }, { "cls_id": "homologset.agr.MGI:1858622", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9Z2P8-1", "uniprot_id": "VAMP5_MOUSE", "id": "Q9Z2P8-1", "name": "Vesicle-associated membrane protein 5", "aln": "MAG--KELKQCQQQADEVTEIMLNNFDKVLERHGKLAELEQRSDQLLDMSSAFSKTTKTLAQQKRWENIRCRVYLGLAVAVGLLIILIVLLVVFLP--SGGDSSKP--------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9Z2J5-1", "uniprot_id": "VAMP5_RAT", "id": "Q9Z2J5-1", "name": "Vesicle-associated membrane protein 5", "aln": "MAG--KELERCQRQADQVTEIMLNNFDKVLERDGKLSELQQRSDQLLDMSSAFSKTTKTLAQQKRWENIRCRVYLGLAVAGGLLLILVVLLVIFLP--SGEDSSKP--------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O95183-1", "uniprot_id": "VAMP5_HUMAN", "id": "O95183-1", "name": "Vesicle-associated membrane protein 5", "aln": "MAG--IELERCQQQANEVTEIMRNNFGKVLERGVKLAELQQRSDQLLDMSSTFNKTTQNLAQKKCWENIRYRICVGLVVVGVLLIILIVLLVVFLP--QSSDSSSAPRTQDAGIASGPGN", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A2BG37-1", "uniprot_id": "A2BG37_DANRE", "id": "A2BG37-1", "name": "", "aln": "MQNGNSRLSEAQKDVEEVKGIMLDNLNKAEERSGKLKELETRADDLLVKGKAFSKTATKVKQKKRWENIKYKVVIAAVAAAVLLGIILAVALSFSNDDNGKDASTTTTTKAP--------", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* . .*...*::.::*. ** :*:.*. ** ** **: *:*:** ..:*.**: .: *:* ****: :: :. ... ** *::.: : * .. *:*.. ", "identical_positions": 33, "similar_positions": 44, "identity": "27.5%" }, { "cls_id": "homologset.agr.MGI:1858683", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9UBF2-1", "uniprot_id": "COPG2_HUMAN", "id": "Q9UBF2-1", "name": "Coatomer subunit gamma-2", "aln": "-----MIKKFDKKDEESGSGSNPFQHLEKSAVLQEAR-IFNETPINPRRCLHILTKILYLLNQGEHFGTTEATEAFFAMTRLFQSNDQTLRRMCYLTIKEMATISEDVIIVTSSLTKDMTGKEDVYRGPAIRALCRITDGTMLQAIERYMKQAIVDKVSSVSSSALVSSLHMMKISYDVVKRWINEAQEAAS----------------SDNIMVQYHALGVLYHLRKNDRLAVSKMLNKFTKSG-LKSQFAYCMLIRIASRLLKE----TEDGHESPLFDFIESCLRNKHEMVIYEAASAIIHLPNCTARELAP-----AVSVLQLFCSSPKPALRYAAVRTLNKVAMKHPSAVTACNLDLENLITDSNRSIATLAITTLLKTGSESSVDRLMKQISSFVSEISDEFKVVVVQAISALCQKYPRKHSVMMTFLSNMLRD-DGGFEYKRAIVDCIISIVEENPESKEAGLAHLCEFIEDCEHTVLATKILHLLGKEGPRTPVPSKYIRFIFNRVVLENEAVRAAAVSALAKFGAQ--NESLLPSILVLLQRCMMDTDDEVRDRATFYLNVLQQRQMA---LNATYIFNGLTVSVPGMEKALHQYTLEPSE---KPFDMKSIP-------------LAMAPVFEQKAEITLVATK--PEKLAPSRQDI-------------------FQEQLAAIPEFLNIGPLFKSSEPVQLTEAETEYFVRCIKHMFTNHIVFQFDCTNTLNDQLLEKVTVQMEPSDS----YEVLSCIPAPSLPYNQPGICYTLVRLPDDDPTAVAGSFSCTMKFTVRDCDPNTGVPD--EDGYDDEYVLEDLEVTVSDHIQKVLKPNFAAAWEEVG--DTFEKEETFALSSTKTLEEAVNNIITFLGMQPCERSDKVPENKNSHSLYLAG--IFRGGYDLLVRSRLALADGVTMQVTVRSKERTPVDVILASVG-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9QXK3-1", "uniprot_id": "COPG2_MOUSE", "id": "Q9QXK3-1", "name": "Coatomer subunit gamma-2", "aln": "-----MIKKFDKKDEESGSGSNPFQHLEKSAVLQEAR-IFNETPINPRRCLHILTKILYLLNQGEHFGTMEATEAFFAMTRLFQSNDQTLRRMCYLTIKEMATISEDVIIVTSSLTKDMTGKEDVYRGPAIRALCRITDGTMLQAVERYMKQAIVDKVSSVASSALVSSLHMMKISYDVVKRWINEAQEAAS----------------SDNIMVQYHALGVLYHLRKNDRLAVSKMLNKFTKSG-LKSQFAYCMLIRIASRLLKE----SEDGHESPLFDFIESCLRNKHEMVIYEAASAIIHLPNCTARELAP-----AVSVLQLFCSSPKPALRYAAVRTLNKVAMKHPSAVTACNLDLENLITDSNRSIATLAITTLLKTGSESSVDRLMKQISSFVSEISDEFKVVVVQAISALCHKYPRKHSVMMTFLSNMLRD-DGGFEYKKAIVDCIISIVEENPESKEAGLAHLCEFIEDCEHTVLATKILHLLGKEGPRTPVPSKYIRFIFNRVVLENEAVRAAAVSALAKFGAQ--NESLLPSILVLLQRCMMDTDDEVRDRATFYLNVLQQRQMA---LNATYIFNGLTVSIPGMEKALHQYTLEPSE---KPFDMKSIP-------------LAMAPVFEQKSEITLVTPK--PEKLAPSRQDI-------------------FQEQLAAIPEFMNLGPLFKSSEPVQLTEAETEYFVRCVKHMFTDHIVFQFDCTNTLNDQLLEKVTVQMEPSDS----YEVLCCIPAPSLPYNQPGICYTLVRLPDEDPTAVAGTFSCTMKFTVRDCDPNTGVPD--EDGYDDEYVLEDLEVTVSDHIQKILKPNFAAAWEEVG--DAFEKEETFALSSTKTLEEAVNNIITFLGMQPCERSDKVPENKNSHSLYLAG--VYRGGYDLLVRSRLALADGVTMQVTVRSKERTPVDVILASVG-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D4ABY2-1", "uniprot_id": "COPG2_RAT", "id": "D4ABY2-1", "name": "Coatomer subunit gamma-2", "aln": "-----MIKKFDKKDEESGSGSNPFQHLEKSAVLQEAR-IFNETPINPRRCLHILTKILYLLNQGEHFGTMEATEAFFAMTRLFQSNDQTLRRMCYLTIKEMATISEDVIIVTSSLTKDMTGKEDVYRGPAIRALCRITDGTMLQAIERYMKQAIVDKVSSVSSSALVSSLHMMKISYDVVKRWINEAQEAAS----------------SDNIMVQYHALGVLYHLRKNDRLAVSKMLNKFTKSG-LKSQFAYCMLIRIASRLLKE----SEDGHESPLFDFIESCLRNKHEMVIYEAASAIIHLPNCTARELAP-----AVSVLQLFCSSPKPALRYAAVRTLNKVAMKHPSAVTACNLDLENLITDSNRSIATLAITTLLKTGSESSVDRLMKQISSFVSEISDEFKVVVVQAIS-LCQKYPRKHSVMMTFLSNMLRD-DGGFEYKKAIVDCIISIVEENPESKEAGLAHLCEFIEDCEHTVLATKILHLLGKEGPRTPVPSKYIRFIFNRVVLENEAVRAAAVSALAKFGAQ--NESLLPSILVLLQRCMMDTDDEVRDRATFYLNVLQQRQMA---LNATYIFNGLTVSIPGMEKALHQYTLEPSE---KPFDMKSIP-------------LAMAPVFEQKSEITLVTPK--PEKLAPSRQDI-------------------FQEQLAAIPEFVNLGPLFKSSEPVQLTEAETEYFVRCVKHMFTDHIVFQFDCTNTLNDQLLEKVTVQMEPSDS----YEVLCCVPAPSLPYNQPGICYTLVRLPDEDPTA------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9PUE4-1", "uniprot_id": "COPG2_DANRE", "id": "Q9PUE4-1", "name": "Coatomer subunit gamma-2", "aln": "-----MIKKFDKKDEESGSGSNPFQHLEKSAVLQEAR-IFNETPINPRRCLHILTKIIYLLNQGEHFGTTEATEAFFAMTRLFQSNDQTLRRMCYLTIKEMANISEDVIIVTSSLTKDMTGKEDVYRGPAIRALCRITDTTMLQAIERYMKQAIVDKVPSVSSSALVSSLHMVKMSFDVVKRWVNEAQEAAS----------------SDNIMVQYHALGLLYHLRKNDRLAVTKMLNKFTKSG-LKSPFAYCMMIRIASKLLEE----TEGGHDSPLFDFIESCLRNKHEMVVYEAASAIVHMPNCTARELAP-----AVSVLQLFCSSPKAALRYAAVRTLNKVAMKHPSAVTACNLDLENLITDSNRSIATLAITTLLKTGSESSVDRLMKQISSFVSEISDEFKVVVVQAISALCQKYPRKHSVMMNFLSNMLRD-DGGFEYKRAIVDCIISIIEENPESKETGLAHLCEFIEDCEHTVLATKILHLLGKEGPRTPTPSKYIRFIFNRVVLESEAVRAAAVSALAKFGAQ--NDDLLPSVLVLMQRCMMDSDDEVRDRATFYMNVLQQKQKA---LNAAYIFNGLSVSVLGLEKSLHQYTLEPSE---KPFDMKTVP-------------LATAPITEHKTEIAPVATSKLPEKLAPSRQDI-------------------YQEQLSAIPEFQGLGPLFKSSEPVQLTEAETEYVVRCIKHTFANHMIFQFDCTNTLNDQLLQKVLVQMEPSES----YEVLHYVPAANLPYSQPGSCYSLVRLPEDDPTAVSCTFSCTMKYLVRDCDPNTGEPD--DDGYDDEYVLEDLEVTVADHIQKVLKPNFAAAWDEVG--DECEKEETFALATVRTLDEAVNNIVSFLGMQPCERSDKVPENKNSHVLFLAG--VFRGGHDVLVRARLALADGVTIQVTVRSTDDNVVDVILASVG-", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q8I0G5-1", "uniprot_id": "COPG_DROME", "id": "Q8I0G5-1", "name": "Coatomer subunit gamma", "aln": "MNYFSLTSHKKHRGHPSAGPSNAYQNLEKTSVLQETR-TFNETPVNPRKCIHILTKILYLINQGEQLVAREATDCFFAMTKLFQSKDVVLRRMVYLGIKELSSIAEDVIIVTSSLTKDMTGKEDLYRAAAIRALCSITDNTMLQAVERYMKQCIVDKNAAVSCAALVSSLRLANTAGDVVKRWANEAQEALN----------------SDNIMVQYHALGLLYHIRKSDRLAVSKLVNKLTRGS-LKSPYAVCMLIRIACKLIEEEDIPSEELSDSPLFTFIESCLRHKSEMVIYEAAHAIVNLKNTNPRMLSP-----AFSILQLFCSSPKATLRFAAVRTLNKVAMTHPAAVTTCNLDLEGLITDSNRSVATLAITTLLKTGAESSVERLMKQISTFVAEISDEFKVVVVQAICALCTKYPRKHTVLMNFLSGMLRE-EGGLEYKTSIVDTIITIIEENADAKESGLSHLCEFIEDCEHVSLAVRILHLLGKEGPFAATPSKYIRFIYNRVILESPIVRAAAVTAMAQFGAS--CPALLSNILVLLGRCQMDPDDEVRDRATYYLSILNSERPE---LYKNYIIERENCSLALLEKSLVEHLNGDVD---TRFDISIVP-------------KAAIVKPVIANDVMLVTSS-APRPPKITREEE-------------------SAARLAQLPGIQVLGPIHRSTAPIQLTESETEYTVQCIKHIFGQHVVFQFDCLNTLSDQILENVRVELTLPEG----FTTRAVIPCPKLPYNDLQTTFVIVEFPPDAANSIA-TFGATLRFVVKDCDPNTGEPES-EEGYDDEYMLEDLELTVADQIQKTRKNNFQVSWDAADSEEWLQAEDTFVLSAVTTLQDAVNTIVKILGLGAANLSENVPEGTHLHTLLCSG--TFRGGAEILVRAKLALSEGVTLNLTVRSTDQDVAELITAAIG-", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P32074-1", "uniprot_id": "COPG_YEAST", "id": "P32074-1", "name": "Coatomer subunit gamma", "aln": "-----MSAHTYKKFENSTSG----DLPDKMTIYQDCMNTFNESPVNSKRCRLLISRLLRLLAQGETFPQNEATALFFSISKLFQHQNDPLRQAVYLAIKELSGISEDVLMATSSIMKDVQNGSDLIKPDAIRSLTYVLDESTAFSAERLLKSAVVSRHPSISSAALCTSYHLLPISEVTIRRFTNETQEAVLDLKQFPNQHGNSEYYPNSTYISQYHALGLLYQLKKTDKMALLKLVRHFSENNSMKNQLAKVELVKIVNDLIYR-----DPQLFSQFRPLLSDWLSNKFESVQLETAKLITSFATRNSRLVAPELYAAAISALQSLLTVPRVSSRFAALRILNRISMVSPEKIVVCNPELESLINDSNRNISTYAITTLLKTGTSKNISSLISTITNFIHDVSDDFKIIIIDAVRTLSLNFPQEWKSILNFLIDVLKNSEGGFKFKNSIVEALIDIVSFVPQSKELALENLCDFIEDCEFNEILVRILHLLGKEGPSAPNPSLYVRHIYNRVVLENSIIRSAAVVALSKFALTKNDPTLYESIISLLKRIANDKDDEVRDRATIALEFIDSARNKDDVIAQNLIESKYFYDIPSLESKLSSYISSNTDSFATAFDVNQVRKFTEDEMKAINLKRKQEQIFNQKSETTLDTTP-EAESVPEKRADANSFAGPNLDDHQEDLLATKYADELLSIEQIKPFGQLVNSSRAISLTEPEAEFVVRGVKHLFKDNVVLQFNITNTLTDIALDNVSVVCTPEISDEAELEELFTLQVDRLLPSEEAACYVAFKKLD---EIVMEGFLNNLTFTTKEINPDTNEPFDGDEGFQDEYEIDSIFLNAGDYVKSSFTGNFSATFDELP----CEEVAVFNIQEDLSIQEVVDKIILNSSCLPVESTQFAPSDSNSHTLKLFGKSALTGSKVALQIKMIKSSKGLALKVHGKGEDSLLCSDLVNGLMQ", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : :: . * . : :* :: *: ***:*:*.::* :::::: *: *** : *** **::::*** :: **: ** ***:: *:***::.***: **: . .*: : ***:* : * : : ** :*..:*.: .:::.:** :* :: : .::*: **:*** ... : ******:**:::*.*::*: *::.:::... :*. * :::*. *: . : * : ::.. * :* * * *:* * : . ..* ::* *.* ** : : *: : *:**:* **:::* * :..** :**.**.****.::* *********:...:. *:. *:.*: ::**:**:::::*: *. ::*:: . ::.** .:*:: :**:::* :**: :* *:. .::** .* :**:******. : .:********** :. ** *:*.*:***:**. :*:*** *:::*. * .:: *: * * ********* :..::. : : * . .: :*. * .: : . **:. : : :. .. .* : .* : : :* : .*: .:.***.*:*: *: :** * :::::**: ***.* *::* * . : * .: : .. ", "identical_positions": 213, "similar_positions": 257, "identity": "22.26%" }, { "cls_id": "homologset.agr.MGI:1858696", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9QZE5-1", "uniprot_id": "COPG1_MOUSE", "id": "Q9QZE5-1", "name": "Coatomer subunit gamma-1", "aln": "-----MLKKFDKKDEESGGGSNPLQHLEKSAVLQEAR-VFNETPINPRKCAHILTKILYLINQGEHLGTTEATEAFFAMTKLFQSNDPTLRRMCYLTIKEMSCIAEDVIIVTSSLTKDMTGKEDNYRGPAVRALCQITDSTMLQAVERYMKQAIVDKVPSVSSSALVSSLHLLKCSFDVVKRWVNEAQEAAS----------------SDNIMVQYHALGLLYHVRKNDRLAVSKMISKFTRHG-LKSPFAYCMMIRVASKQLEEEDGSR----DSPLFDFIESCLRNKHEMVVYEAASAIVNLPG-----CSAKELAPAVSVLQLFCSSPKAALRYAAVRTLNKVAMKHPSAVTACNLDLENLVTDSNRSIATLAITTLLKTGSESSIDRLMKQISSFMSEISDEFKVVVVQAISALCQKYPRKHAVLMNFLFTMLRE-EGGFEYKRAIVDCIISIIEENSESKETGLSHLCEFIEDCEFTVLATRILHLLGQEGPKTNNPSKYIRFIYNRVVLEHEEVRAGAVSALAKFGAQ--NEEMLPSILVLLKRCVMDDDNEVRDRATFYLNVLEQKQKA---LNAGYILNGLTVSIPGLEKALQQYTLEPSE---KPFDLKSVP-------------------------------LATTPMAEQRPESTATAAVKQPEKVAATRQEIFQEQLAAVPEFQGLGPLFKSSPEPVALTESETEYVIRCTKHTFSDHLVFQFDCTNTLNDQTLENVTVQMEPTE----AYEVLSYVPARSLPYNQPGTCYTLVALPTEDPTAVACTFSCVMKFTVKDCDPNTGEID--EEGYEDEYVLEDLEVTVADHIQKVMKVNFEAAWDEVGDE--FEKEETFTLSTIKTLEEAVGNIVKFLGMHPCERSDKVPENKNTHTLLLAG--VFRGGHDILVRSRLLLLDTVTMQVTARSSEELPVDIILASVG-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q4AEF8-1", "uniprot_id": "COPG1_RAT", "id": "Q4AEF8-1", "name": "Coatomer subunit gamma-1", "aln": "-----MLKKFDKKDEESGGGSNPLQHLEKSAVLQEAR-VFNETPINPRKCAHILTKILYLINQGEHLGTTEATEAFFAMTKLFQSNDPTLRRMCYLTIKEMSCIAEDVIIVTSSLTKDMTGKEDNYRGPAVRALCQITDSTMLQAVERYMKQAIVDKVPSVSSSALVSSLHLLKCSFDVVKRWVNEAQEAAS----------------SDNIMVQYHALGLLYHVRKNDRLAVSKMISKFTRHG-LKSPFAYCMMIRVASKQLEEEDGSR----DSPLFDFIESCLRNKHEMVVYEAASAIVNLPG-----CSAKELAPAVSVLQLFCSSPKAALRYAAVRTLNKVAMKHPSAVTACNLDLENLVTDSNRSIATLAITTLLKTGSESSIDRLMKQISSFMSEISDEFKVVVVQAISALCQKYPRKHAVLMNFLFTMLRE-EGGFEYKRAIVDCIISIIEENSESKETGLSHLCEFIEDCEFTVLATRILHLLGQEGPKTNNPSKYIRFIYNRVVLEHEEVRAGAVSALAKFGAQ--NEEMLPSILVLLKRCVMDDDNEVRDRATFYLNVLEQKQKA---LNAGYILNGLTVSIPGLEKALQQYTLEPSE---KPFDLKSVP-------------------------------LATTPMTEQRPESTSTAAVKQPEKVAATRQEIFQEQLAAVPEFQGLGPLFKSSPEPVALTESETEYVIRCTKHTFSDHLVFQFDCTNTLNDQTLENVTVQMEPTE----AYEVLSYVPVRSLPYNQPGTCYTLVALPKEDPTAVACTFSCVMKFTVKDCDPNTGEID--EEGYEDEYVLEDLEVTVADHIQKVMKVNFEAAWDEVGDE--FEKEETFTLSTIKTLEEAVGNIVKFLGMHPCERSDKVPENKNTHTLLLAG--VFRGGHDILVRSRLLLLDTVTMQVTARSSEELPVDIILASVG-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9Y678-1", "uniprot_id": "COPG1_HUMAN", "id": "Q9Y678-1", "name": "Coatomer subunit gamma-1", "aln": "-----MLKKFDKKDEESGGGSNPFQHLEKSAVLQEAR-VFNETPINPRKCAHILTKILYLINQGEHLGTTEATEAFFAMTKLFQSNDPTLRRMCYLTIKEMSCIAEDVIIVTSSLTKDMTGKEDNYRGPAVRALCQITDSTMLQAIERYMKQAIVDKVPSVSSSALVSSLHLLKCSFDVVKRWVNEAQEAAS----------------SDNIMVQYHALGLLYHVRKNDRLAVNKMISKVTRHG-LKSPFAYCMMIRVASKQLEEEDGSR----DSPLFDFIESCLRNKHEMVVYEAASAIVNLPG-----CSAKELAPAVSVLQLFCSSPKAALRYAAVRTLNKVAMKHPSAVTACNLDLENLVTDSNRSIATLAITTLLKTGSESSIDRLMKQISSFMSEISDEFKVVVVQAISALCQKYPRKHAVLMNFLFTMLRE-EGGFEYKRAIVDCIISIIEENSESKETGLSHLCEFIEDCEFTVLATRILHLLGQEGPKTTNPSKYIRFIYNRVVLEHEEVRAGAVSALAKFGAQ--NEEMLPSILVLLKRCVMDDDNEVRDRATFYLNVLEQKQKA---LNAGYILNGLTVSIPGLERALQQYTLEPSE---KPFDLKSVP-------------------------------LATAPMAEQRTESTPITAVKQPEKVAATRQEIFQEQLAAVPEFRGLGPLFKSSPEPVALTESETEYVIRCTKHTFTNHMVFQFDCTNTLNDQTLENVTVQMEPTE----AYEVLCYVPARSLPYNQPGTCYTLVALPKEDPTAVACTFSCMMKFTVKDCDPTTGETD--DEGYEDEYVLEDLEVTVADHIQKVMKLNFEAAWDEVGDE--FEKEETFTLSTIKTLEEAVGNIVKFLGMHPCERSDKVPDNKNTHTLLLAG--VFRGGHDILVRSRLLLLDTVTMQVTARSLEELPVDIILASVG-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9PUE4-1", "uniprot_id": "COPG2_DANRE", "id": "Q9PUE4-1", "name": "Coatomer subunit gamma-2", "aln": "-----MIKKFDKKDEESGSGSNPFQHLEKSAVLQEAR-IFNETPINPRRCLHILTKIIYLLNQGEHFGTTEATEAFFAMTRLFQSNDQTLRRMCYLTIKEMANISEDVIIVTSSLTKDMTGKEDVYRGPAIRALCRITDTTMLQAIERYMKQAIVDKVPSVSSSALVSSLHMVKMSFDVVKRWVNEAQEAAS----------------SDNIMVQYHALGLLYHLRKNDRLAVTKMLNKFTKSG-LKSPFAYCMMIRIASKLLEETEGGH----DSPLFDFIESCLRNKHEMVVYEAASAIVHMPN-----CTARELAPAVSVLQLFCSSPKAALRYAAVRTLNKVAMKHPSAVTACNLDLENLITDSNRSIATLAITTLLKTGSESSVDRLMKQISSFVSEISDEFKVVVVQAISALCQKYPRKHSVMMNFLSNMLRD-DGGFEYKRAIVDCIISIIEENPESKETGLAHLCEFIEDCEHTVLATKILHLLGKEGPRTPTPSKYIRFIFNRVVLESEAVRAAAVSALAKFGAQ--NDDLLPSVLVLMQRCMMDSDDEVRDRATFYMNVLQQKQKA---LNAAYIFNGLSVSVLGLEKSLHQYTLEPSE---KPFDMKTVP-------------------------------LATAPITEHKTEIAPVATSKLPEKLAPSRQDIYQEQLSAIPEFQGLGPLFKSS-EPVQLTEAETEYVVRCIKHTFANHMIFQFDCTNTLNDQLLQKVLVQMEPSE----SYEVLHYVPAANLPYSQPGSCYSLVRLPEDDPTAVSCTFSCTMKYLVRDCDPNTGEPD--DDGYDDEYVLEDLEVTVADHIQKVLKPNFAAAWDEVGDE--CEKEETFALATVRTLDEAVNNIVSFLGMQPCERSDKVPENKNSHVLFLAG--VFRGGHDVLVRARLALADGVTIQVTVRSTDDNVVDVILASVG-", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q8I0G5-1", "uniprot_id": "COPG_DROME", "id": "Q8I0G5-1", "name": "Coatomer subunit gamma", "aln": "MNYFSLTSHKKHRGHPSAGPSNAYQNLEKTSVLQETR-TFNETPVNPRKCIHILTKILYLINQGEQLVAREATDCFFAMTKLFQSKDVVLRRMVYLGIKELSSIAEDVIIVTSSLTKDMTGKEDLYRAAAIRALCSITDNTMLQAVERYMKQCIVDKNAAVSCAALVSSLRLANTAGDVVKRWANEAQEALN----------------SDNIMVQYHALGLLYHIRKSDRLAVSKLVNKLTRGS-LKSPYAVCMLIRIACKLIEEEDIPSEELSDSPLFTFIESCLRHKSEMVIYEAAHAIVNLKN-----TNPRMLSPAFSILQLFCSSPKATLRFAAVRTLNKVAMTHPAAVTTCNLDLEGLITDSNRSVATLAITTLLKTGAESSVERLMKQISTFVAEISDEFKVVVVQAICALCTKYPRKHTVLMNFLSGMLRE-EGGLEYKTSIVDTIITIIEENADAKESGLSHLCEFIEDCEHVSLAVRILHLLGKEGPFAATPSKYIRFIYNRVILESPIVRAAAVTAMAQFGAS--CPALLSNILVLLGRCQMDPDDEVRDRATYYLSILNSERPE---LYKNYIIERENCSLALLEKSLVEHLNGDVD---TRFDISIVP-------------------------------KAAIVKPVIANDVMLVTSS-APRPPKITREEESAARLAQLPGIQVLGPIHRST-APIQLTESETEYTVQCIKHIFGQHVVFQFDCLNTLSDQILENVRVELTLPE----GFTTRAVIPCPKLPYNDLQTTFVIVEFPPDAANSIA-TFGATLRFVVKDCDPNTGEPES-EEGYDDEYMLEDLELTVADQIQKTRKNNFQVSWDAADSEEWLQAEDTFVLSAVTTLQDAVNTIVKILGLGAANLSENVPEGTHLHTLLCSG--TFRGGAEILVRAKLALSEGVTLNLTVRSTDQDVAELITAAIG-", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P32074-1", "uniprot_id": "COPG_YEAST", "id": "P32074-1", "name": "Coatomer subunit gamma", "aln": "-----MSAHTYKKFENSTSG----DLPDKMTIYQDCMNTFNESPVNSKRCRLLISRLLRLLAQGETFPQNEATALFFSISKLFQHQNDPLRQAVYLAIKELSGISEDVLMATSSIMKDVQNGSDLIKPDAIRSLTYVLDESTAFSAERLLKSAVVSRHPSISSAALCTSYHLLPISEVTIRRFTNETQEAVLDLKQFPNQHGNSEYYPNSTYISQYHALGLLYQLKKTDKMALLKLVRHFSENNSMKNQLAKVELVKIVNDLIYRDPQLF-----SQFRPLLSDWLSNKFESVQLETAKLITSFATRNSRLVAPELYAAAISALQSLLTVPRVSSRFAALRILNRISMVSPEKIVVCNPELESLINDSNRNISTYAITTLLKTGTSKNISSLISTITNFIHDVSDDFKIIIIDAVRTLSLNFPQEWKSILNFLIDVLKNSEGGFKFKNSIVEALIDIVSFVPQSKELALENLCDFIEDCEFNEILVRILHLLGKEGPSAPNPSLYVRHIYNRVVLENSIIRSAAVVALSKFALTKNDPTLYESIISLLKRIANDKDDEVRDRATIALEFIDSARNKDDVIAQNLIESKYFYDIPSLESKLSSYISSNTDSFATAFDVNQVRKFTEDEMKAINLKRKQEQIFNQKSETTLDTTPEAESVPEKRADANSFAGPNLDDHQEDLLATKYADELLSIEQIKPFGQLVNSS-RAISLTEPEAEFVVRGVKHLFKDNVVLQFNITNTLTDIALDNVSVVCTPEISDEAELEELFTLQVDRLLPSEEAACYVAFKKLD---EIVMEGFLNNLTFTTKEINPDTNEPFDGDEGFQDEYEIDSIFLNAGDYVKSSFTGNFSATFDELPCE----EVAVFNIQEDLSIQEVVDKIILNSSCLPVESTQFAPSDSNSHTLKLFGKSALTGSKVALQIKMIKSSKGLALKVHGKGEDSLLCSDLVNGLMQ", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : :: . * . : :* :: *: ***:*:*.::* :::::: *: *** : *** **::::*** :: **: ** ***:: *:***::.***: **: . .* : *:*:* : * : : ** :*..:*.: .::*.:** :* :: : .::*:.**:*** ... : *********:::*.*::*: *:: :.:. . :*. * ::::. . : . * : ::.. * :* * * *:* *. : .. :.*.* ** : : *:.: *:**:* **:::* * :..** :**.*:.****.::* *********:...:. *:. *:.*: ::**:**:::::*: :*. ::*:: ::*** :*:: :**:::* :**: :* *:. .::** .* :**:******. : .:******:*** : .** *:*.*:***:** :*:.** *:::*. : .:: *: * * *:******* :..::. : : * . .: ** * .: : . **:. * : . : : .* : :: :* : .*: .: ***.*:*:.:: ** * :::::**: ***.* *::* * : * .: : : . : * : : .:: :* *.* ::*::*** ::.: :...* ::. . ** .::* * .* : ::::.*..*: . . : :: .*...: *.* * .: *. * : . ::::: :. :. . : .: ", "identical_positions": 228, "similar_positions": 318, "identity": "23.82%" }, { "cls_id": "homologset.agr.MGI:1858730", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O70480-1", "uniprot_id": "VAMP4_MOUSE", "id": "O70480-1", "name": "Vesicle-associated membrane protein 4", "aln": "MPPKFKRHLNDDDVTGSVKSERRNLLEDDSDEEEDFFLRGPSGPRFGPRNDKIKHVQNQVDEVIDVMQENITKVIERGERLDELQDKSESLSDNATAFSNRSKQLRRQMWWRGCKIKAIMALAAAILLLMIIILIVVKFRT", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0ABK0KYT3-1", "uniprot_id": "A0ABK0KYT3_RAT", "id": "A0ABK0KYT3-1", "name": "Vesicle-associated membrane protein 4", "aln": "MPPKFKRHLNDDDVTGSVKSERRNLLEDDSDEEEDFFLRGPSGPRFGPRNDKIKHVQNQVDEVIDVMQENITKVIERGERLDELQDKSESLSDNATAFSNRSKQLRRQMWWRGCKIKAIMALAAAILLLMIIILIVVKYRT", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O75379-1", "uniprot_id": "VAMP4_HUMAN", "id": "O75379-1", "name": "Vesicle-associated membrane protein 4", "aln": "MPPKFKRHLNDDDVTGSVKSERRNLLEDDSDEEEDFFLRGPSGPRFGPRNDKIKHVQNQVDEVIDVMQENITKVIERGERLDELQDKSESLSDNATAFSNRSKQLRRQMWWRGCKIKAIMALVAAILLLVIIILIVMKYRT", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P31109-1", "uniprot_id": "SNC1_YEAST", "id": "P31109-1", "name": "Synaptobrevin homolog 1", "aln": "-------------MSSSTPFDPYALSEHD-----------EERPQNVQSKSRTAELQAEIDDTVGIMRDNINKVAERGERLTSIEDKADNLAVSAQGFKRGANRVRKAMWYKDLKMKMCLALVIIILLVVIIVPIAVHFSR", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P33328-1", "uniprot_id": "SNC2_YEAST", "id": "P33328-1", "name": "Synaptobrevin homolog 2", "aln": "-------------MSSSVPYDPYVPPEES-----------NSG-ANPNSQNKTAALRQEIDDTVGIMRDNINKVAERGERLTSIEDKADNLAISAQGFKRGANRVRKQMWWKDLKMRMCLFLVVIILLVVIIVPIVVHFS-", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ::.*. : *.. . :.: :: ::*:.:.:*::**.** ****** .::**::.*: .* .*.. ::::*: **::. *:: : *. ***::**: *.::: ", "identical_positions": 30, "similar_positions": 53, "identity": "21.28%" }, { "cls_id": "homologset.agr.MGI:1858732", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P57790-1", "uniprot_id": "KEAP1_RAT", "id": "P57790-1", "name": "Kelch-like ECH-associated protein 1", "aln": "-MQPEPKPSGAPRSSQFLPLWSKCPEGAGDAVMYASTECKAEVTPSQ--DGNRTFS----------YTLEDHTKQAFGIMNELRLSQQLCDVTLQVKYEDIP-AAQFMAHKVVLASSSPVFKAMFTNGLREQGMEVVSIEGIHPKVMERLIEFAYTASISVGEKCVLHVMNGAVMYQIDSVVRACSDFLVQQLDPSNAIGIANFAEQIGCTELHQRAREYIYMHFGEVAKQEEFFNLSHCQLATLISRDDLNVRCESEVFHACIDWVKYDCPQRRFYVQALLRAVRCHALTPRFLQTQLQKCEILQADARCKDYLVQIFQELTLHKPTQAVPCRAPKVGRLIYTAGGYFRQSLSYLEAYNPSNGSWLRLADLQVPRSGLAGCVVGGLLYAVGGRNNSPDGNTDSSALDCYNPMTNQWSPCASLSVPRNRSGGGVIDGHIYAVGGSHGCIHHSSVERYEPDRDEWHLVAPMLTRRIGVGVAVLNRLLYAVGGFDGTNRLNSAECYYPERNEWRMITPMNTIRSGAGVCVLHSCIYAAGGYDGQDQLNSVERYDVETETWTFVASMKHRRSALGIAVHQGRIYVLGGYDGHTFLDSVECYDPDTDTWSEVTRLTSGRSGVGVAVTMEPCRKQIDQQNCTC-------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9Z2X8-1", "uniprot_id": "KEAP1_MOUSE", "id": "Q9Z2X8-1", "name": "Kelch-like ECH-associated protein 1", "aln": "-MQPEPKLSGAPRSSQFLPLWSKCPEGAGDAVMYASTECKAEVTPSQ--DGNRTFS----------YTLEDHTKQAFGVMNELRLSQQLCDVTLQVKYEDIP-AAQFMAHKVVLASSSPVFKAMFTNGLREQGMEVVSIEGIHPKVMERLIEFAYTASISVGEKCVLHVMNGAVMYQIDSVVRACSDFLVQQLDPSNAIGIANFAEQIGCTELHQRAREYIYMHFGEVAKQEEFFNLSHCQLATLISRDDLNVRCESEVFHACIDWVKYDCPQRRFYVQALLRAVRCHALTPRFLQTQLQKCEILQADARCKDYLVQIFQELTLHKPTQAVPCRAPKVGRLIYTAGGYFRQSLSYLEAYNPSNGSWLRLADLQVPRSGLAGCVVGGLLYAVGGRNNSPDGNTDSSALDCYNPMTNQWSPCASMSVPRNRIGVGVIDGHIYAVGGSHGCIHHSSVERYEPERDEWHLVAPMLTRRIGVGVAVLNRLLYAVGGFDGTNRLNSAECYYPERNEWRMITPMNTIRSGAGVCVLHNCIYAAGGYDGQDQLNSVERYDVETETWTFVAPMRHHRSALGITVHQGKIYVLGGYDGHTFLDSVECYDPDSDTWSEVTRMTSGRSGVGVAVTMEPCRKQIDQQNCTC-------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q14145-1", "uniprot_id": "KEAP1_HUMAN", "id": "Q14145-1", "name": "Kelch-like ECH-associated protein 1", "aln": "-MQPDPRPSGAGACCRFLPLQSQCPEGAGDAVMYASTECKAEVTPSQ--HGNRTFS----------YTLEDHTKQAFGIMNELRLSQQLCDVTLQVKYQDAP-AAQFMAHKVVLASSSPVFKAMFTNGLREQGMEVVSIEGIHPKVMERLIEFAYTASISMGEKCVLHVMNGAVMYQIDSVVRACSDFLVQQLDPSNAIGIANFAEQIGCVELHQRAREYIYMHFGEVAKQEEFFNLSHCQLVTLISRDDLNVRCESEVFHACINWVKYDCEQRRFYVQALLRAVRCHSLTPNFLQMQLQKCEILQSDSRCKDYLVKIFEELTLHKPTQVMPCRAPKVGRLIYTAGGYFRQSLSYLEAYNPSDGTWLRLADLQVPRSGLAGCVVGGLLYAVGGRNNSPDGNTDSSALDCYNPMTNQWSPCAPMSVPRNRIGVGVIDGHIYAVGGSHGCIHHNSVERYEPERDEWHLVAPMLTRRIGVGVAVLNRLLYAVGGFDGTNRLNSAECYYPERNEWRMITAMNTIRSGAGVCVLHNCIYAAGGYDGQDQLNSVERYDVETETWTFVAPMKHRRSALGITVHQGRIYVLGGYDGHTFLDSVECYDPDTDTWSEVTRMTSGRSGVGVAVTMEPCRKQIDQQNCTC-------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A2R8Q1W5-1", "uniprot_id": "KEP1B_DANRE", "id": "A0A2R8Q1W5-1", "name": "Kelch-like ECH-associated protein 1B", "aln": "-----------------------------------MTECKAEVTPSAS-NGHRVFS----------YTLESHTAAAFAIMNELRRERQLCDVTLRVRYCPLDTHVDFVAHKVVLASSSPVFRAMFTNGLKECGMEVVPIEGIHPKVMGRLIEFAYTASISVGEKCVIHVMNGAVMYQIDSVVQACCDFLVEQLDPSNAIGIASFAEQIGCTELHQKAREYIYMNFSQVATQEEFFTLSHCQLVTLISRDELNVRCESEVFHACVAWVQYDREERRPYVQALLQAVRCHSLTPHFLQRQLEH---FEWDAQSKDYLSQIFRDLTLHKPTKVIPLRTPKVPQLIYTVGGYFRQSLSFLEAFNPCSGAWLRLADLQVPRSGLAACVISGLLYAVGGRNNGPDGNMDSHTLDCYNPMNNCWRPCAHMSVPRNRIGVGVIDGMIYAVGGSHGCTHHNSVERYDPERDSWQLVSPMLTRRIGVGVAVINRLLYAVGGFDGTHRLSSAECYNPERDEWRSIAAMNTVRSGAGVCALGNYIYVMGGYDGTNQLNTVERYDVEKDSWSFSASMRHRRSALGVTTHHGRIYVLGGYDGNTFLDSVECFDPETDSWTEVTHMKSGRSGVGVAVTMEPCHKELIP--CQC-------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q1ECZ2-1", "uniprot_id": "KEP1A_DANRE", "id": "Q1ECZ2-1", "name": "Kelch-like ECH-associated protein 1A", "aln": "---------------------MICPR---KKRPIKDEDFSAIVVPSM--RGHGYLD----------YTVESHPSKALQNMDELRHHEMLCDLVLHVTYKDKI--VDFKVHKLVLAASSPYFKAMFTSNFKECHASEVTLRDVCPQVISRLIDFAYTSRITVGETCVLHVLLTAMRYQMEEVAKACCDFLMKNLEPSNVIGISRFAEEIGCTDLHLRTREYINTHFNEVTKEEEFFSLSHCQLLELISQDSLKVLCESEVYKACIDWVRWDAESRAQYFHALLNAVHIYALPPTFLKRQLQSCPILSKANSCKDFLSKIFHEMALRKPLPPTPHRG---TQLIYIAGGYKQHSLDTLEAFDPHKNVWLKLGSMMSPCSGLGACVLFGLLYTVGGRNLSLQNNTESGSLSCYNPMTNQWTQLAPLNTPRNRVGVGVIDGSIYAVGGSHASTHHNSVERYDPETNRWTFVAPMSVARLGAGVAACGGCLYVVGGFDGDNRWNTVERYQPDTNTWQHVAPMNTVRSGLGVVCMDNYLYAVGGYDGQTQLKTMERYNITRDVWEPMASMNHCRSAHGVSVYQCKIFVLGGFNQGGFLSSVECYCPASNVWTLVTDMPVGRSGMGVAVTMEPCPGILPEEEEEVDEEM---------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q7KSF5-1", "uniprot_id": "Q7KSF5_DROME", "id": "Q7KSF5-1", "name": "", "aln": "MQTQMHSPMQYETHISDMPNHKGYPCRPEEAEMSNTSESCSISCGGRFGSAHSTLDDHDATDDDMTFCMSNYAKEALKMMYMMRSHGMLTDVVLEVKKELFP------AHKVVLSAASPYFKAMFTGGLKESEMSRVQLQGVCPTAMSRILYFMYTGQIRVTEVTVCQLLPAATMFQVPNVIDACCAFLERQLDPTNAIGIAHFAEQHGCVELQKKANVFIERNFTQVCQEEEFLQLSAYQLIALIRRDELNVQEEREVYNAVLKWVKYDEDNRHCKMEHILGAVRCQFLTPNFLKEQMKNCDVLRKVPACREYLAKIFKDLTLHK-CPGVKERTPNTTRMIFVAGGFFRHSLDILEAYNVDDMTWTTLANLRIPRSGLGAAFLKGKFYAVGGRNNNIGSSYDSDWVDRYSAVTETWRPCAPMSVPRHRVGVAVMDELMYAVGGSAGMEYHNTVEYYDPDLDRWTLVQPMHAKRLGVGVVVVNRLLYAIGGFDGNERLASVECYHPENNEWSFLPPLQTGRSGAGVAAINQYIYVVGGFDGTRQLATVERYDTENDTWDMVAPIQIARSALSLTPLDEKLYAIGGFDGNNFLSIVEVYDPRTNTWTTGTPLKSGRSGHASAVIYQPACSTTFMDYEDSDAPHPDGSNNGERNAHTPQNTYGSGSPHYPGTASNMQFHTSYGMSGCNNCDSEMDIKPYIPAEHHSFQIPAIRSEELVNPNCPWSRMQERFRRTPPASFTDDERNANDMRHKLKKAQKECLFSTAAKVFHHHIEGRLRKLTSAAT", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : . .: :. : :..:. *: * :* * *:.*.* .**:**:::** *:****..::* . * :..: * .: *:: * **. * : * * ::: * :*: .* **. ** .:*:*:*.***: ***: **.:*: ::. :* :* :* :***: ** ** ** :*.*:* * **::* : **::* .* .. :* **: *.* **: *:: : .:::* :**.:::*:* * ::*: .**: ::**. ***:: . * *..: * ***....: * :*:***** . .. :* :. *..:.: * * :..**:* * .*:* :****** . :*.:** *:*: : * :* ** . *:*.**.. . **.:***** .* :.* * *: : * :..::* *** ** : . :*. **:** ** ::***: : * *.:. *** .:: . :::.:**:: **. ** : * :: *: * : **** . ** :*. ", "identical_positions": 183, "similar_positions": 189, "identity": "23.37%" }, { "cls_id": "homologset.agr.MGI:1858745", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9WVS0-1", "uniprot_id": "ICOS_MOUSE", "id": "Q9WVS0-1", "name": "Inducible T-cell costimulator", "aln": "MKPYFCRVFVFCFLIRLLTGEINGSADHRMFSFHNGGVQISCKYPETVQQLKMRLFREREVLCELTKTKGSGNAVSIKNPMLCLYHLSNNSVSFFLNNPDSSQGSYYFCSLSIFDPPPFQERNLSGGYLHIYESQLCCQLKLWLPVGCAAFVVVLLFGCILIIWFSKKKYGSSVHDPNSEYMFMAAVNTNKKSRLAGVTS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9R1T7-1", "uniprot_id": "ICOS_RAT", "id": "Q9R1T7-1", "name": "Inducible T-cell costimulator", "aln": "MKPYFSCVFVFCFLIKLLTGELNDLANHRMFSFHDGGVQISCNYPETVQQLKMQLFKDREVLCDLTKTKGSGNTVSIKNPMSCPYQLSNNSVSFFLDNADSSQGSYFLCSLSIFDPPPFQEKNLSGGYLLIYESQLCCQLKLWLPVGCAAFVAALLFGCIFIVWFAKKKYRSSVHDPNSEYMFMAAVNTNKKSRLAGMTS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9Y6W8-1", "uniprot_id": "ICOS_HUMAN", "id": "Q9Y6W8-1", "name": "Inducible T-cell costimulator", "aln": "MKSGLWYFFLFCLRIKVLTGEINGSANYEMFIFHNGGVQILCKYPDIVQQFKMQLLKGGQILCDLTKTKGSGNTVSIKSLKFCHSQLSNNSVSFFLYNLDHSHANYYFCNLSIFDPPPFKVT-LTGGYLHIYESQLCCQLKFWLPIGCAAFVVVCILGCILICWLTKKKYSSSVHDPNGEYMFMRAVNTAKKSRLTDVTL", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "**. : .*:**: *::****:*. *::.** **:***** *:**: ***:**:*:: ::**:*********:****. * :********** * * *:..*::*.*********: *:**** ***********:***:******.. ::***:* *::**** *******.***** **** *****:.:* ", "identical_positions": 126, "similar_positions": 46, "identity": "63.0%" }, { "cls_id": "homologset.agr.MGI:1858746", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I6GLZ3-1", "uniprot_id": "A0A8I6GLZ3_RAT", "id": "A0A8I6GLZ3-1", "name": "histone acetyltransferase", "aln": "-----MVKLANPLYTEWILEAVQKIKKQKQRPSEERICHAVSTSHGLDKKTVSEQLELSVQDGSVLKVTNKGLASYKDPDHPGRFSSVKPGTFPKPTKGPKGPPCNDLRNVDWNKLLKRAIEGLEEPSGSSLKSIEKYLRSQSDLTGTTDHPAFQQRLRLGAKRAVNNGRLLKDGPQYRVNTGSSDGRGAPQYPSAFPSSLPPVSLLPHEKDQPRADPIPICSFCLGTKESNREKKPEELVSCADCGSSGHPSCLKFCPELTANVKALRWQCIECKTCSACRVQGKNADNMLFCDSCDRGFHMECCDPPLSRMPKGMWICQVCRPKKK-GRKLLHEKAAQIKRRYAKPIGRPKNKLKQRLLSVTSDEGSVNAFTGRGSPGRGQKTKVCTTPSSGHAASGKDSSSRLAVTDPTRPGATTKTTTSSTYISASTLKVNKKTKGLIDGLTKFFTPSPDGRRSRGEIIDFSKHYRPRKKVSQKQSCTSHMLATGTTQKLKPPPSALPPPAPISGQSPSSQ---KSSTSTSSAPTQSSSSRSSEPSFSSLINSSQLKALFDGLSHIYTTQGQSRKKGHPSYAPPKRMRRKTEFSSTAKAKACFFGKRDFR----SRFLSHSSCS-WGMTRGHIFKAIAHFKRTTFLKKHRMLGRLKYKVTPQMGTPSPGKGSLADGRINPDQDNDTEIKISIKQESMDVNVMGNKDLVTEEDLDVFKQAQELSWEKIECESGVED---------CGRYPSVIEFGKYEIQTWYSSPYPQEYARLPKLYLCEFCLKYMKSKNILLRHSKKCGWFHPPANEIYRRKDLSVFEVDGNMSKIYCQNLCLLAKLFLDHKTLYYDVEPFLFYVLTKNDEKG---------CHLVGYFSKEKLCQQKYNVSCIMIMPQHQRQGFGRFLIDFSYLLSRREGQAGSPEKPLSDLGRLSYLAYWKSVILEYLYRHH-ERHISIKAISRATGMCPHDIATTLQYLHMIDRRDGRFVIIRRE------KLILGHMEKLKNCSRPNEVDPESLRWTPILISNAVVSEEEREAEKEAERLMEQASCWEKEEQENLSSRVTSRQSSAKVQSKNKYLHSPERRPVAGERGQLLGLSKESSEEEEEEEDDEDEEEEEE------------------EEE-SIPTSPPRLTKPQSVSIKRKRPFVVKKKRGRKRRRINSSVTTETISETTEVLNEPFDNSDE----ERPMPRLEPTCEIQVEEAGRKPVLRKAFQHQPGKKRQTEEGDGKDNHFFKNAALCRNDVDDDAEHL------EEGSRDSAEPLKCRQVWPKAAKRGLSKWRQSKERRPGLKLNLCTPPETPMEPEGLTKVVKEQKGISEDKGSP--VGEDREVTETEEALLPQDGNGREETGTPVSPHKSPGGKADEEDLIKGEEEEEEEG------------------TTEKDPDGAKSKEKAEAEISMEKE--DAVHLDDHEEDEDEEEEPSHNEDHDADDEDDGHMEATNVDRGDLPKEAFKDALEGQEAFLGLSIQPSHSDPEGLVNCGGDLAVSCGSEPKELAG--DAGTAPESDSE----------------------------------------------------------------LPE-EQTQEQDQEKSNGADTELKDGGTATVEIDSETVQAVQSLTQENREQDDTFQDCAETQEACRSLQNYTHTDQSPQIATTLDECQQSDHSSPVSSVHSHPGQSVRSVNSPS---------------------------VPALENSYAQISPDQTAITVPPLQN-METSPMMDVPSVSDHSQQVVDSGFSDLG---------SIESTTENYENPSSYDSTMGGSICGN-----SSSQNSCSYGSLTSS-SLTQSSCAVTQQMS----NISGSCSMLQQTSISSPPTCSVKSPQGCVVERPPSSSQ-----------------------------------------QLAQCSMAANFTPP-MQLADIPETSN--ANIGLYERMGQSD------------------FGAGHYPQPSATFSLAKLQQLTNTLIDHSLPYSHSA--AATSYAN-SASLSTPLS--NTGLVQLSQSPHSVPGGPQAQATMTPPPNLTPPPMNLPPPLLQRNMAASNIGISHSQRLQTQIASKGP----VSMRTKSASLSPAAATHQSQIYGR----------------SQTVAMQGPARTLTMQRGMNMSVNLMPAPAYNVNSVNMNMNTLNAMNGYSMSQPMMNSGYHSNHGYMNQTPQYPMQMQMGMMGTQPYAQQPMQTP------PHSNMMYTAPGHHGYMNTGMSKQSLNGSYMRR", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8BRB7-1", "uniprot_id": "KAT6B_MOUSE", "id": "Q8BRB7-1", "name": "Histone acetyltransferase KAT6B", "aln": "-----MVKLANPLYTEWILEAVQKIKKQKQRPSEERICHAVSTSHGLDKKTVSEQLELSVQDGSVLKVTNKGLASYKDPDNPGRFSSVKPGTFPKPTKGSKGPPCNDLRNVDWNKLLKRAIEGLEEPNGSSLKNIEKYLRSQSDLTGTTNHPAFQQRLRLGAKRAVNNGRLLKEGPQYRVNSGSSDGKGAPQYPSAFPSSLPPVSLLPHEKDQPRADPIPICSFCLGTKESNREKKPEELLSCADCGSSGHPSCLKFCPELTANVKALRWQCIECKTCSACRVQGKNADNMLFCDSCDRGFHMECCDPPLSRMPKGMWICQVCRPKKK-GRKLLHEKAAQIKRRYAKPIGRPKNKLKQRLLSVTSDEGSMSAFTGRGSPGRGQKTKVSTTPSSGHAASGKHSSSRLAVTDPTRPGATTKTTTSSTYISASTLKVNKKTKGLIDGLTKFFTPSPDGRRSRGEIIDFSKHYRPRKKVSQKQSCTSHVLAT----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------DTDIKISIKQESADVSLVGNKELVTEEDLDVFKQAQELSWEKIECESGVED---------CGRYPSVIEFGKYEIQTWYSSPYPQEYARLPKLYLCEFCLKYMKSKNILLRHSKKCGWFHPPANEIYRRKDLSVFEVDGNMSKIYCQNLCLLAKLFLDHKTLYYDVEPFLFYVLTKNDEKG---------CHLVGYFSKEKLCQQKYNVSCIMIMPQHQRQGFGRFLIDFSYLLSRREGQAGSPEKPLSDLGRLSYLAYWKSVILEYLYRHH-ERHISIKAISRATGMCPHDIATTLQHLHMIDRRDGRFVIIRRE------KLILGHMEKLKNCSRPNELDPESLRWTPMLISNAVVSEEEREAEKEAERLMEQASCWEKEEQEILSSRVSSRQSSAKVQSKNKYLHSPERRPVAGERGQLLELSKESSEEEEEEEEEDDEEEEEE------------------EEEESIQTSPPRLTKPQSVSIKRKRPFVVKKKRGRKRRRINSSVTTETISETTEVLNEPFDNSDE----ERPMPQLEPTCEIPVEEGGRKPVLRKAFPHQPGKKRQTEEEEGEDNHFFKTAALCRKDVDDDAEHL------KEGSKDNPEPLKCRQVWPKGAKRGLSKWKQSKERKTGFKLNLYTPPETPMEPEDQVTIE-EQKELSEDKGSP--VGMEREVTETVDALLPQEGSRREETGIPVSPHKSPGGKVDEEDLIRGEEEGEEEGEEEGEREEQEEEEEV---TTEKDLDGAKSKENPEPEISMEKE--DPVHLGDHEEDEDEEEEPSHNEDHDADDEDDGHMEAANMERGDLPRETFKDALEGQEAFLDLSIQPSHSNPEVLMNCGVDLTMSCNSEPKELAG--DTGTAPESDAE----------------------------------------------------------------PPE-EQTQKQDQKNSDGVDAELEEGGPAAVEIDSETAQAVQSLTQENREHDDTFPDCAETQEACRSLQNYTHTDQSPQIATTLDECQQSDHSSPVSSVHSHPGQSVRSVNSPS---------------------------VPALENSYAQISPDQTAITVPPLQN-METSPMMDVPSVSDHSQQVVDSGFSDLG---------SIESTTENYENPSSYDSTMGGSICGN-----GSSQNSCSYSSLTSS-NLTQNSCAVTQQMS----NISGSCSMLQQTSISSPPTCSVKSPQGCVVERPPSSSQ-----------------------------------------QLAQCSMAANFTPP-MQLADIPETSN--ANIGLYERMGQSD------------------FGAGHYPQPSATFSLAKLQQLTNTLIDHSLPYSHSA--AVTSYAN-SASLSTPLS--NTGLVQLSQSPHSVPGGPQAQATMTPPPNLTPPPMNLPPPLLQRNMAASNIGISHSQRLQTQIASKGH----VSMRTKAASLSPAAATHQSQIYGR----------------SQTVAMQGPARTLTMQRGMNMSVNLMPAPAYNVNSVNMNMNTLNAMNGYSMSQPMMNSGYHSNHGYMNQTPQYPMQMQMGMMGSQPYAQQPMQTP------PHANMMYTAPGHHGYMNTGMSKQSLNGSYMRR", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8WYB5-1", "uniprot_id": "KAT6B_HUMAN", "id": "Q8WYB5-1", "name": "Histone acetyltransferase KAT6B", "aln": "-----MVKLANPLYTEWILEAIQKIKKQKQRPSEERICHAVSTSHGLDKKTVSEQLELSVQDGSVLKVTNKGLASYKDPDNPGRFSSVKPGTFPKSAKGSRGS-CNDLRNVDWNKLLRRAIEGLEEPNGSSLKNIEKYLRSQSDLTSTTNNPAFQQRLRLGAKRAVNNGRLLKDGPQYRVNYGSLDGKGAPQYPSAFPSSLPPVSLLPHEKDQPRADPIPICSFCLGTKESNREKKPEELLSCADCGSSGHPSCLKFCPELTTNVKALRWQCIECKTCSACRVQGRNADNMLFCDSCDRGFHMECCDPPLSRMPKGMWICQVCRPKKK-GRKLLHEKAAQIKRRYAKPIGRPKNKLKQRLLSVTSDEGSMNAFTGRGSPGRGQKTKVCTTPSSGHAASGKDSSSRLAVTDPTRPGATTKITTTSTYISASTLKVNKKTKGLIDGLTKFFTPSPDGRRSRGEIIDFSKHYRPRKKVSQKQSCTSHVLATGTTQKLKPPPSSLPPPTPISGQSPSSQ---KSSTATSSPSPQSSSSQCSVPSLSSLTTNSQLKALFDGLSHIYTTQGQSRKKGHPSYAPPKRMRRKTELSSTAKSKAHFFGKRDIR----SRFISHSSSSSWGMARGSIFKAIAHFKRTTFLKKHRMLGRLKYKVTPQMGTPSPGKGSLTDGRIKPDQDDDTEIKINIKQESADVNVIGNKDVVTEEDLDVFKQAQELSWEKIECESGVED---------CGRYPSVIEFGKYEIQTWYSSPYPQEYARLPKLYLCEFCLKYMKSKNILLRHSKKCGWFHPPANEIYRRKDLSVFEVDGNMSKIYCQNLCLLAKLFLDHKTLYYDVEPFLFYVLTKNDEKG---------CHLVGYFSKEKLCQQKYNVSCIMIMPQHQRQGFGRFLIDFSYLLSRREGQAGSPEKPLSDLGRLSYLAYWKSVILEYLYHHH-ERHISIKAISRATGMCPHDIATTLQHLHMIDKRDGRFVIIRRE------KLILSHMEKLKTCSRANELDPDSLRWTPILISNAAVSEEEREAEKEAERLMEQASCWEKEEQEILSTRANSRQSPAKVQSKNKYLHSPESRPVTGERGQLLELSKESSEEEEEEEDEEEEEEEEEEEEDEEEEEEEEE----EEEEENIQSSPPRLTKPQSVAIKRKRPFVLKKKRGRKRRRINSSVTTETISETTEVLNEPFDNSDE----ERPMPQLEPTCEIEVEEDGRKPVLRKAFQHQPGKKRQTEEEEGKDNHCFKNADPCRNNMNDDSSNL------KEGSKDNPEPLKCKQVWPKGTKRGLSKWRQNKERKTGFKLNLYTPPETPMEPDEQVTVE-EQKETSEGKTSPSPIRIEEEVKETGEALLPQEENRREETCAPVSPNTSPGEKP-EDDLIKPEEEEEEEEEEEEEEEEEEGEEEEGGGNVEKDPDGAKSQEKEEPEISTEKE--DSARLDDHEEEEEEDEEPSHNEDHDADDEDDSHMESAEVEKEELPRESFKEVLENQETFLDLNVQPGHSNPEVLMDCGVDLTASCNSEPKELAG--DPEAVPESDEE----------------------------------------------------------------PPPGEQAQKQDQKNSKEVDTEFKEGNPATMEIDSETVQAVQSLTQESSEQDDTFQDCAETQEACRSLQNYTRADQSPQIATTLDDCQQSDHSSPVSSVHSHPGQSVRSVNSPS---------------------------VPALENSYAQISPDQSAISVPSLQN-METSPMMDVPSVSDHSQQVVDSGFSDLG---------SIESTTENYENPSSYDSTMGGSICGN-----GSSQNSCSYSNLTSS-SLTQSSCAVTQQMS----NISGSCSMLQQTSISSPPTCSVKSPQGCVVERPPSSSQ-----------------------------------------QLAQCSMAANFTPP-MQLAEIPETSN--ANIGLYERMGQSD------------------FGAGHYPQPSATFSLAKLQQLTNTLIDHSLPYSHSA--AVTSYAN-SASLSTPLS--NTGLVQLSQSPHSVPGGPQAQATMTPPPNLTPPPMNLPPPLLQRNMAASNIGISHSQRLQTQIASKGH----ISMRTKSASLSPAAATHQSQIYGR----------------SQTVAMQGPARTLTMQRGMNMSVNLMPAPAYNVNSVNMNMNTLNAMNGYSMSQPMMNSGYHSNHGYMNQTPQYPMQMQMGMMGTQPYAQQPMQTP------PHGNMMYTAPGHHGYMNTGMSKQSLNGSYMRR", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M3BER5-1", "uniprot_id": "A0A8M3BER5_DANRE", "id": "A0A8M3BER5-1", "name": "histone acetyltransferase", "aln": "-----MVKLANPLYTEWILEAIQKIKRQKQRPSEERICHAVSSTRGLDKGVVLHQLELAVKDGSILKVTSKGCASYKDPDNPGRITPFKLGGSGTVSVGSVIP-AGDLRHVDWNKILRRAIEGLGVPSGSSLRNIERFLRSQGDLVNVVANPRFQQRLRLAAKRAVNNGRLLKDGPLYRLNSGGLGGKSCFRNVGVFGVDLPPVTLLPHERDQPRADPIPICSFCLGTKESNRDKRPEELLSCADCGSSGHPSCLKFSADLTANVKALRWQCIECKTCSSCQIQGKNADEMLFCDSCDRGFHMECCDPPLSRMPKGMWICQVCRPKEQEGKRLLHKTAAQIKRRYAKP-GRPRKNLAHPTMSDSGGPGSV-ELSEKARHGRGSISTFCTPPSS---------STFIPTTD----GRSLTDPLTSTPTLTTLPPINKKTKGLIDGLSKFFTPSPLGRRLRGEASGSSNQHRPRKRGYRKHHASMMTPGVR----LNAPSSVLLTPSPSQGHSPISLNPTQSSSPSSAHSPHSSSSQSSGPSLSSLPGNSQLKGLFDGLSHIFTTQGQSRQKGLPSYAPPKRVRRTQDMSTSPKMSLQLQGKKPVKGFCSKLASLASSASGWPPKRGRPFKSALHFKRTPILRKHKLLGRFRFKASPQRENITPGKGRLADGRVKPDPNHAFNVERCLRREPQEGRMTLVNDHVAEEDLKLFRHVKELTAKKNGGDQ--------------GQSPPLIEFGKYEIQTWYSSPYPPEYLRLPKLYLCEFCLKYMKSQDILQRHSKKCGWFHPPANEIYRKDNLSVFEVDGNISKIFCQNLCLLAKLFLDHKTLYYDVEPFLFYVLTQNDEKG---------CHLVGYFSKEKLCQQKYNVSCIMIMPQFQRQGFGRFLIDFSYLLSRLEGQAGSPEKPLSDLGRLSYLAYWKSVILEYLHNHP-DKSVSIRGMSRATGMCPHDIATTLQQLNMIDFQDGRFVIIQRH------QLIEEHMDRLRVKPRLHEVDPDCLSWTPALVCRSPPVDLKSALALQARDHRADYTASTRNLAMGMG-YIGTRPPLTKCKNFRRRYSDP---LFGNSTGKDFEVSEESSSDDDDDNNDDDDDDEDG-------------------EDSAVQSQS-------GQGLKRRRAPTMRRKRGRRRTRINSSVTTETILERTEVLDEPFENSDV----ESPLPEHSRRCCSEDEEEEKS---QRSAVCRPGRPRTNEE----DNHSNQ----------SKEEEN------VEVKKDNPRPAKRKKGWPKGVKRGPPKWR-LKERKMGFKLNLYTPPETPMVTVEQEQDD-EQDASPASFSGP---------CQSFRESRPEDPELDTCVSVPPSPEPPKSHKVNEDESTDKSDTVENSPSADDTNETTPGPID----DPEQSTQNAEELEDLKPEGETEGRPVKGSGEGDEEEDEDEEPEPSHLDDHDADDEDDSHEQRMEDPVPLPERDLTEDTEPSPSNNNNKQPEEQPSPGEPPSHCSEELASESALVNLGMQDGDTVDSDHTPDSE----------------------------------------------------------------TEEEDNLEKPEEKQMGPLTPAIKEDHNICPELDMETAQAVQSLTQES-EQERHFQDCAETQEACHSLQRYVHVEQSPQMTP-VDDCQQSDHSSPLSSVHSHPSQSVRSVNSPA---------------------------VSILESGYTQISPDQGTVSVHSLHNNMETSPIMDVPSVSDHSQQVVDSGFSDLG---------SIESTTENYENPSSYDSTLGNSICGTGAGAGASSQSSCSYGNLSSGGSHSQSSCAVSQQMAGPVVNNTGACSMLQQTSMSSPQGCSVKSPQGCVPERQPSHSHGHGH--GHGHGHGHSHSHHHSHHQHHPHHQHHQHPQHQYQQPLSHCSMPASFPPPPMQLPDIPESNNPSTNLGLYDRMGQGE------------------YGTGHYG------HLHKLQQLTNTIMDHSLPFSHSASHSIPSYANNNGSLSTQLGPHNPTLVSLSQP----GGGPQSQSTVTPPPNMTPPPM-----MLQRNMATPNMNLAPSQRLQTQMPPKNHHHHPVSIRSKSAPLPP---HHQQQMYGRG---------------PQSVAMQAPGRTLAMPTRMNMGVNLMPAPAYNVNSMNVNVN--MAMNTYRVTQPMMNGGYHGNPTYMNQSPQY--SMQMGMMGTQPYPQQPMQAP------PHGNMMYSPAGHHSYVNTGMSKQPLNGPYMRR", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P34218-1", "uniprot_id": "SAS3_YEAST", "id": "P34218-1", "name": "Histone acetyltransferase SAS3", "aln": "----------------------MSLTANDESPKPKKNALLKN-----------------------LEIDDLIHSQFVRSDTNG----------------------------------HRTTRRLFNSDASISHRIRGSVRSDKGLN-KIKKGLISQQSKLASENSSQN----------------IVNRDNKMGAVSFPIIEPNIEVSEELKVRIKYDSIKFFNFER-------------LISKSSVIAPLVNKNITSSGPLIG---------FQRRVNRLKQTWDLATENMEYPYSSDN-------------------------------TPFRDNDSWQWYVPYGGTIKKMKDFSTKRTLPTWEDKIKFLTFLE-----------------------------------------------------------NSKSATYINGNVSLCNHNETDQENEDRKKRKGKVPRIKNKVWFS-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------QIEYIVLRNYEIKPWYTSPFPEHINQNKMVFICEFCLKYMTSRYTFYRHQLKCLTFKPPGNEIYRDGKLSVWEIDGRENVLYCQNLCLLAKCFINSKTLYYDVEPFIFYILTEREDTENHPYQNAAKFHFVGYFSKEKFNSNDYNLSCILTLPIYQRKGYGQFLMEFSYLLSRKESKFGTPEKPLSDLGLLTYRTFWKIKCAEVLLKLR-DSARRRSNNKNEDTFQQVSLNDIAKLTGMIPTD----VVFGLE------QLQVLYRHKTRSLSSLDDFN-----------------------------YIIKIDSWNRIENIYKTWSSKNYPR----VKYDKLLWEPIILGPSFGINGMMNLEPTALADEALTNETMAPVISNN------------------------------------THIENYNNSRAHNKRRRRRRRSSEHKTSKLHVNNIIEPEVPATDFFE----DTVSSLTEYMCDYKNTN--------------------------------------------NDRLI------YQAEKRVLESIHDRKGIPRSKFSTETHWELCFTIKN---------SETPLG---------------------------------------NHAARRNDTGISSLEQDEVENDVDTELYVG---------------------------------ENAKEDEDEDEDFTLDDD-------IEDEQISEENDEEEDTYEEDSDDDEDGKRKGQEQDENDIESHIRKERVRKRRKITLIEDDEE--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "Q9W1A9-1", "uniprot_id": "Q9W1A9_DROME", "id": "Q9W1A9-1", "name": "histone acetyltransferase", "aln": "MMRESAHDINMDTWNQWILEAISKIRSQKQRPSVQRICQAIGTHHKFHEDIVAEKLEKAVESGAVIKVYNKGLHSYKAPMAKRRVKVDKN--------------------TNLYKLVAKAVHDLGECEGSTIKSIENYIQK-FNCIDLSPNVDFKAVIKASIKKAVDAGFLIQEGKLYKKGKSLTTPRKCAPVSEVVIKGEESCTHCSGNSQKNLNGIPEPLSSCKQCG---------ISLHTTCANIAGRCKSQSYVLLYMLVTKGTIWDCQNCADCAVCKMRNR-GPCLLQCFVCKDHFHLTCLDTIPDKKPKHPYRCKTCSKQGFDTPKLVKKDNSRIKMEAERMTPSYKYASNKRQSIKKDGNIESPSTSKLCVYNDGNGQRRKVPASLSSRKMNHSEDQFEFPSKQKRSQILQGGYLASQETRKRTFSDLSSTSSSSESEDEDDEDDDRNRNGDDNDQDESTSSDSCTSSSSDSDSSESSSDTSEWDDEYDEEEDYDTDRSTIREKNVFESGKQSCAKLSTGDGLGSPQNNELGSENWGFAAVAKNPIDIFVKSKHNSNVKGIGYSKPAASTFATSPAANRVQKSTPVASSTPEKNSAPIGGMTIKRQTANGQKKKIVPLKSMPLEAGKSYEKCEDDIPYLTEETVMKVQLLEEIERSRETHSQADGKREMNNDEDAPGESTKRANPFENQPLPPGVTATDVELYQEVLHKAVVQMSNNHIEKVNDVSLKSGQNTQSPKSIQIGKWDIETWYSSPFPQEYARLLKLFLCEFCLKYTKSRSVLDRHQNKCIWKQPPGTEIFRQGNISVFEVDGNVNKIYCQNLCLLAKFFLDHKTLYYDVEPFLFYILTKNDQSG---------CHLVGYFSKEKHCTQKYNVSCILTMPQYQRQGYGRFLIDFSYLLSREEGQLGTPEKPLSDLGRLSYFSYWKSVVLEYLYKHRNYTKITFKDIAIKTGLAISDIALAFELLNFIKLRKNDGDIRYQINVKIEWKKVLAHHNKMANSKTRIIIEPDCLRWSPLLSVSKLPNIIKPISNREYLSNQMETNSSFKEINEDKISVKQGVSTSSKVNQESSELSTKNRGPSSEKLIDERENQRKRAYPEEFLKSASNEAKKPKLTAPQPNLEDQSFGELSDSSDCKSSKDLSEQLTKRAQRLAKRNDLIPHTNKRKHFDRPLENNTTSTDHNPPAQSQADTAGTENGHKSEETAAKENCKNVVEKEHVDKPVNIMPKLRGKQSNGKRSEEPQFNENPTSDPVAVASLSPAKEITREPVKVAKTESPGKNQESAKHDAEPNSVSDQVLDAVAKKTKKTLFSDVASYNTEDVKYNSEEKPMAIAQEPKESPTEAGIKETKPLEVPEQKAKAKSPEKPATVAETVLQHVHAPVNTEKISTEESKLELDVHYLKLSPDSALNPPVASVQKPVPEPPAPKEKAKDLQAAQPSEALQKQ----PEIEMVKKTETKTETPVSNPPSNRTDVSSLVEQPVKAAPEKVEQPMVKEAVDIKDKALKKPVPDVPVVKPEATSCEKKIDHSKTKVFHEKEAIKTDQQLVQVKEEEKSNARAPSAPIPIRDKIQLKGNEHAQLQNSIPSQFPLNQMPNYHTSQYWQWEYYGYNLSHLDASQKGQKQFHKDLATTMAYTHNFTQNLYQSANLAMQHAHHQMHQTKEKHKVERKNSGKKEEQNKVVSSVNVVSTAREDAHVQHCNEYAANNQAALYNQKCASQQKQAQQMKSLANVQNPVPRQSNSNAPESTVLMPNPVISQAGSVPAKQKVEHGVNSTSVISREGKLNKIGHSNIHATAQHANLQVGGGQSDVNPNMVYNTESSANSAMQHYDCGISAQINMDSPANIGSAIAHGPQEISATSNVHMHQPHRQFSDCSMQNQPVTTPMHMSIQNSHMQQQNNLNLNLAPEGSSNINLLSNPQHQHQSRKLNAQADIAVSSPTPSHRATTPKQIRSGNTQQRDAKNAAPPTTTTNTHHQIPQGGAAANISKSHHDSLHNLQFSQHGHQQNMQPIDYVPIPQISQNFSANPSNYDIVGMPAVIQQRMSLNGSVHSLANSHQRIEQPSSACAVNNFYLQNNMPAAENAPRVPVSSSLGGPPTAGNNDQRQAGQDSITTANSSGATASLAGNLCSLSKLQQLTNCLESQPCNTSPGAQVNLAPSPHHPIPPNSTPPPHLLMQNRNISTPPNMLQTQVTPLQYKYYPGNMNIPPITSAQNTSRNTRNTPSAPVQHTSTPMGSGNNRTANVHISPNLMAPYGAINSYRMSPQQSPPTGSYSSGGDYPNSQIPMQMMNMQSQYQDACVLQRGTPSNPMYPTYSPYLPLNGSIRR-", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .: :.: *. :: . . ::: . .: . :: . * ..* : *. ::. . : :. : . :.: : : . : . . : : . . . : : . : .. : .: : : : . . ..: :. . . .:. .. .. . . * : :::*:.**:**:* . : :::******* .*: : **. ** :**..**:* .:**:*:**. . ::********* *:: **********:**:**:.::. *:******** :.**:***: :* .**:*:*:**::******* *.: *:********* *:* ::** * * . : .: : :* : : : .: .: . . : . . : :. . : . . : :: :: * . *:. : : . : . . . . : .. : :. :. . . : : *:. : . . : :: . : : * .. : : :: ", "identical_positions": 107, "similar_positions": 203, "identity": "4.58%" }, { "cls_id": "homologset.agr.MGI:1858751", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q99K70-1", "uniprot_id": "RRAGC_MOUSE", "id": "Q99K70-1", "name": "Ras-related GTP-binding protein C", "aln": "MSLQYG-----AEETPLAGSYG-------AADSFP-----------KDFGYGVEEEEE-EAAAGGGG-GAGAGGGCGPGGADSSKPR------ILLMGLRR----SGKSSIQKVVFHKMSPNETLFLESTNKIYKDDISNSSFVNFQIWDFPGQMDFFDPTFDYEMIFRGTGALIYVIDAQDDYMEALTRLHITVSKAYKVNPDMNFEVFIHKVDGLSDDHKIETQRDIHQRANDDLADAGLEKLHLSFYLTSIYDHSIFEAFSKVVQKLIPQLPTLENLLNIFISNSGIEKAFLFDVVSKIYIATDSSPVDMQSYELCCDMIDVVIDVSCIYG---LKEDGSGSAYD------KESMAIIKLNNTTVLYLKEVTKFLALVCILREESFERK---GLIDYNFHCFRKAIHEVFEVGVTSHRS--CSHQTSAPS--------LKALAHNGTPRNAI", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9HB90-1", "uniprot_id": "RRAGC_HUMAN", "id": "Q9HB90-1", "name": "Ras-related GTP-binding protein C", "aln": "MSLQYG-----AEETPLAGSYG-------AADSFP-----------KDFGYGVEEEEE-EAAAAGGGVGAGAGGGCGPGGADSSKPR------ILLMGLRR----SGKSSIQKVVFHKMSPNETLFLESTNKIYKDDISNSSFVNFQIWDFPGQMDFFDPTFDYEMIFRGTGALIYVIDAQDDYMEALTRLHITVSKAYKVNPDMNFEVFIHKVDGLSDDHKIETQRDIHQRANDDLADAGLEKLHLSFYLTSIYDHSIFEAFSKVVQKLIPQLPTLENLLNIFISNSGIEKAFLFDVVSKIYIATDSSPVDMQSYELCCDMIDVVIDVSCIYG---LKEDGSGSAYD------KESMAIIKLNNTTVLYLKEVTKFLALVCILREESFERK---GLIDYNFHCFRKAIHEVFEVGVTSHRS--CGHQTSASS--------LKALTHNGTPRNAI", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0ABK0LH83-1", "uniprot_id": "A0ABK0LH83_RAT", "id": "A0ABK0LH83-1", "name": "Ras-related GTP-binding protein", "aln": "MPRTRPPVLGLAGPTALRSSYSGGPRGWRPGAAFRGTVHTCERGAWARFAQGSRPGPPGSTSSADGRAGRGGDAGWREEAGAGHRPRTPPFWSLPLWHWRNRPAVPGSHVEKLVVFHKMSPNETLFLESTNKIYKDDISNSSFVNFQIWDFPGQMDFFDPTFDYEMIFRGTGALIYVIDAQDDYMEALTRLHITVSKAYKVNPDMNFEVFIHKVDGLSDDHKIETQRDIHQRANDDLADAGLEKLHLSFYLTSIYDHSIFEAFSKVVQKLIPQLPTLENLLNIFISNSGIEKAFLFDVVSKIYIATDSSPVDMQSYELCCDMIDVVIDVSCIYG---LKEDGSGSAYD------KESMAIIKLNNTTVLYLKEVTKFLALVCILREESFERK---GLIDYNFHCFRKAIHEVFEVGVTSHRS--CSHQTSAPS--------LKALAHNGTPRNAI", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0A0R4IZL6-1", "uniprot_id": "A0A0R4IZL6_DANRE", "id": "A0A0R4IZL6-1", "name": "Ras-related GTP-binding protein", "aln": "MSIEYE--------EQLAGSLV---------DSFP-----------KDFGYGVENMDMMQENLENSP-------------SADNKPR------ILLMGLRR----SGKSSIQKVVFHKMSPNETLFLESTNKIYKDDISGSSFVNFHIWDFPGQVDFFDPTFDYEMIFRGTGALIFVIDAQDDYVEALGRLHLTVSRAFRVNPEINFEVFIHKVDGLSDDHKIETQRDIHQRANDDLADASLEKLHLSFYLTSIYDHSIFEAFSKVVQKLIPQLPTLENLLNIFISNSGIEKAFLFDVVSKIYIATDSSPVDMQSYELCCDMIDVVIDVSCIYG---LKDEGNGNAYD------KESLAIIKLNNTTVLYLKEVTKFLALVCILREESFERK---GLIDYNFHCFRKAIHEVFEVSGSTQRMGGATVQSSPPSCSGNGLSRLKSTALNGTPRSLV", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P53290-1", "uniprot_id": "RAGCD_YEAST", "id": "P53290-1", "name": "GTP-binding protein GTR2", "aln": "MSLEAT----------------------------------------------------------------------------DSKAM------VLLMGVRR----CGKSSICKVVFHNMQPLDTLYLESTSNPSLEHFS--TLIDLAVMELPGQLNYFEPSYDSERLFKSVGALVYVIDSQDEYINAITNLAMIIEYAYKVNPSINIEVLIHKVDGLSEDFKVDAQRDIMQRTGEELLELGLDGVQVSFYLTSIFDHSIYEAFSRIVQKLIPELSFLENMLDNLIQHSKIEKAFLFDVNSKIYVSTDSNPVDIQMYEVCSEFIDVTIDLFDLYKAPVLRNSQKSSDKDNVINPRNELQNVSQLANGVIIYLRQMIRGLALVAIIRPNGTDMESCLTVADYNIDIFKKGLEDIWANARASQAK-------------------------NSIEDDV-", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*. . :. : * *. *. ****:*.* :**:****.: :.:* ::::: : ::***:::*:*::* * :*:..***::***:**:*::*: .* : :. *::***.:*:**:********:*.*:::**** **:.::* : .*: :::*******:****:****::******:*. ***:*: :*.:* ********* ****::***.***:* **:*.::***.**: :* *::. ... * :* : :* * .::**::: : ****.*:* :. : : : ***:. *:*.:.::: . ::: *. . ", "identical_positions": 137, "similar_positions": 126, "identity": "30.11%" }, { "cls_id": "homologset.agr.MGI:1858752", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "F1LRZ9-1", "uniprot_id": "F1LRZ9_RAT", "id": "F1LRZ9-1", "name": "RUN domain-containing protein 3A", "aln": "MEASFVQTTMALGLPSKKASSRNVIVERRNLITVCRFSVKTLLEKYTAEPIDDSSEEFVNFAAILEQILSHRFKACAPAGPVSWFSSDGQRGFWDYIRLACSKVPNNCVSSIENMENISTARAKGRAWIRVALMEKRMSEYITTALRDNRTTRRFYDSGAIMLREEATVLTGMLIGLSAIDFSFCLKGEVLDGKTPVVIDYTPYLKFTQSYDYLTDEEERHSAESSTSEDNSPEHPYLPLVTDEDSWYNKWHKMEQKFRIVYAQKGYLEELVRLRESQLKDLEAENRRLQLQLEEAAAQNQREKRELEGVILELQEQLPDPPPPPRTGLIPGDHAPLAQGSKELTTALVNQWPSLSTLSRPEGASNSKLFRRHSFMSTEPLSAEASLSSDSQRLGEGKRDEEPWGPIG--------------SSEPN---------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O08576-1", "uniprot_id": "RUN3A_MOUSE", "id": "O08576-1", "name": "RUN domain-containing protein 3A", "aln": "MEASFVQTTMALGLPSKKASSRNVIVERRNLITVCRFSVKTLLEKYTAEPIDDSSEEFVNFAAILEQILSHRFKACAPAGPASWFSSDGQRGFWDYIRLACSKVPNNCVSSIENMENISTARAKGRAWIRVALMEKRMSEYITTALRDNRTTRRFYDSGAIMLREEATVLTGMLIGLSAIDFSFCLKGEVLDGKTPVVIDYTPYLKFTQSYDYLTDEEERHSAESSTSEDNSPEHPYLPLVTDEDSWYNKWHKMEQKFRIVYAQKGYLEELVRLRESQLKDLEAENRRLQLQLEEAAAQNQREKRELEGVILELQEQL--------TGLIPGDHAPLAQGSKELTTSLVNQWPSLSTLHRPEGASNSKLYRRHSFMSTEPLSAEASLSSDSQRLGEAKRDEEPWGPIGKDPTPSMLGLCGSLASIPSCKSLASFKSNECLVSDSPEGSPALSPS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q59EK9-1", "uniprot_id": "RUN3A_HUMAN", "id": "Q59EK9-1", "name": "RUN domain-containing protein 3A", "aln": "MEASFVQTTMALGLSSKKASSRNVAVERKNLITVCRFSVKTLLEKYTAEPIDDSSEEFVNFAAILEQILSHRFKACAPAGPVSWFSSDGQRGFWDYIRLACSKVPNNCVSSIENMENISTARAKGRAWIRVALMEKRMSEYITTALRDTRTTRRFYDSGAIMLRDEATILTGMLIGLSAIDFSFCLKGEVLDGKTPVVIDYTPYLKFTQSYDYLTDEEERHSAESSTSEDNSPEHPYLPLVTDEDSWYSKWHKMEQKFRIVYAQKGYLEELVRLRESQLKDLEAENRRLQLQLEEAAAQNQREKRELEGVILELQEQL--------TGLIPSDHAPLAQGSKELTTPLVNQWPSLGTLNGAEGASNSKLYRRHSFMSTEPLSAEASLSSDSQRLGEGTRDEEPWGPIGKDPTPSMLGLCGSLASIPSCKSLASFKSNECLVSDSPEGSPALSPS", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A7YDW0-1", "uniprot_id": "RUN3A_DANRE", "id": "A7YDW0-1", "name": "RUN domain-containing protein 3A", "aln": "MEQSFMQSAMAMGAQSKKGFSRSIAVERKNLITVCRFSVKTLLEKYTAEPIDDSSEEFINFAAILEHILSHRFKGSG-----SWF--DGQRSFWDFIRLACSKVPNNCISSIENMENINSSRAKGRAWLRVALMEKRLSEYIATALRDSRTTRRFYDEGAIMLREEATVLTGMLIGLGAIDFSFCLKGEALDGKSEAVIDYTPYLKFTQSYDYLSDDEDGQSVDSSNSDD-SVEHPYIPLVTDEESWRNKCRKMEQRFKIVNAQKGYLEELVRLRESQLKNVEMENKKLTAGLEELQQQSQKEKRELENIILELQEQL--------TSLIPGESHPLS---KDLSIPLVNQWPSLQNYNNQE---DSKLYHRGSFPSPEP---HISLTTGSQRT-ERKQNGKSWCTAEKDYTPSMLGLCGSMSSLPSCKSLPSLRSTECLVNISAEPSPALTPS", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "** **:*::**:* ***. **.: ***:*****************************:*******:*******... *** ****.***:************:*********.::*******:********:****:*****.********.******:***:********.***********.****: .*****************:*:*: :*.:**.*:* * ****:******:** .* :****:*:** ******************::* **::* *** *.*:******.:******** *.***.: **: *:*: .******** . * :***::* ** *.** . **::.*** * .:: :.* . :* *. ", "identical_positions": 275, "similar_positions": 76, "identity": "60.57%" }, { "cls_id": "homologset.agr.MGI:1858896", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9QYY8-1", "uniprot_id": "SPAST_MOUSE", "id": "Q9QYY8-1", "name": "Spastin", "aln": "--------------------------------------MSSPAGRRKKKGSGGAS---------PAPARPPPPAAVPAP-----------------------------AAGPAPAA---------------------------------------------GSPPKRNPSSFSSPLVVGFALLRLLACHLGLLFAWLCQRFSRALMAAKR----------SSGTAPAPASPSPPEPGPGGEA----------------------------------------------ESVRVFHKQAFEYISIALRIDEEEKAGQKEQ---------------------------------AVEWYKKGIEELEKGIAVIVT-GQGEQYERARR------LQAKMMTNLVMAKDRLQLLEKLQPVLQFSKSQTDVYNESTNLTCRNGHLQSESGAVPKR------------------KDPLTHASNSLPRSKTVLKSGSAGLSGHHRAP--------SCSGLSMVSGARPGPGPAATTHKGTPKPNRTNKPSTP--------TTAVRKKKDLKN--------------FRNVDSNLANLIMNEIVDNGTAVKFDDIAGQELAKQALQEIVILPSLRPELFTGLRAPARGLLLFGPPGNGKTMLAKAVAAESNATFFNISAASLTSKYVGEGEKLVRALFAVARELQPSIIFIDEVDSLLCERR-EGEHDASRRLKTEFLIEFDGVQSAGD------------------DRVLVMGATNRPQELDEAVLRRFIKRVYVSLPNEETRLLLLKNLLCKQGSPLTQKELAQLARMTDGYSGSDLTALAKDAALGPIRELKPEQVKNMSASEMRNIRLSDFTESLKKIKRSVSPQTLEAYIRWNKDFGDTTV-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "B2RYN7-1", "uniprot_id": "SPAST_RAT", "id": "B2RYN7-1", "name": "Spastin", "aln": "--------------------------------------MSSPAGRRKKKGSGGAS---------PAPARPPPPAAVPAP-----------------------------AAGPAPAP---------------------------------------------GSPHKRNLYYFSYPLVVGFALLRLLACHLGLLFVWLCQRFSRALMAAKR----------SSGTAPAPASPSTPAPGPGGEA----------------------------------------------ESVRVFHKQAFEYISIALRIDEEEK-GQKEQ---------------------------------AVEWYKKGIEELEKGIAVIVT-GQGEQYERARR------LQAKMMTNLVMAKDRLQLLE--------------------------------SGAVPKK------------------KDPLTHASNSLPRSKTVMKSGSTGLSGHHRAP--------SCSGLSMVSGARPGSGPAATTHKGTSKPNRTNKPSTP--------TTAVRKKKDLKN--------------FRNVDSNLANLIMNEIVDNGTAVKFDDIAGQELAKQALQEIVILPSLRPELFTGLRAPARGLLLFGPPGNGKTMLAKAVAAESNATFFNISAASLTSKYVGEGEKLVRALFAVARELQPSIIFIDEVDSLLCERR-EGEHDASRRLKTEFLIEFDGVQSAGD------------------DRVLVMGATNRPQELDEAVLRRFIKRVYVSLPNEETRLLLLKNLLCKQGSPLTQKELAQLARMTDGYSGSDLTALAKDAALGPIRELKPEQVKNMSASEMRNIRLSDFTESLKKIKRSVSPQTLEAYIRWNKDFGDTTV-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9UBP0-1", "uniprot_id": "SPAST_HUMAN", "id": "Q9UBP0-1", "name": "Spastin", "aln": "--------------------------------------MNSPGGRGKKKGSGGASN--------PVPPRPPPPCLAPAPP----------------------------AAGPAPPP---------------------------------------------ESPHKRNLYYFSYPLFVGFALLRLVAFHLGLLFVWLCQRFSRALMAAKR----------SSGAAPAPASASAPAPVPGGEA----------------------------------------------ERVRVFHKQAFEYISIALRIDEDEKAGQKEQ---------------------------------AVEWYKKGIEELEKGIAVIVT-GQGEQCERARR------LQAKMMTNLVMAKDRLQLLEKMQPVLPFSKSQTDVYNDSTNLACRNGHLQSESGAVPKR------------------KDPLTHTSNSLPRSKTVMKTGSAGLSGHHRAP--------SYSGLSMVSGVKQGSGPAPTTHKGTPKTNRTNKPSTP--------TTATRKKKDLKN--------------FRNVDSNLANLIMNEIVDNGTAVKFDDIAGQDLAKQALQEIVILPSLRPELFTGLRAPARGLLLFGPPGNGKTMLAKAVAAESNATFFNISAASLTSKYVGEGEKLVRALFAVARELQPSIIFIDEVDSLLCERR-EGEHDASRRLKTEFLIEFDGVQSAGD------------------DRVLVMGATNRPQELDEAVLRRFIKRVYVSLPNEETRLLLLKNLLCKQGSPLTQKELAQLARMTDGYSGSDLTALAKDAALGPIRELKPEQVKNMSASEMRNIRLSDFTESLKKIKRSVSPQTLEAYIRWNKDFGDTTV-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6NW58-1", "uniprot_id": "SPAST_DANRE", "id": "Q6NW58-1", "name": "Spastin", "aln": "--------------------------------------MNSG---HKARLRGGR------------------------------------------------------ACGPVSDG---------------------------------------------SARGNRLLFYTRSLSRVPEWLLRVLL----LLLRWLFQPIRRAMAARAK----------ECGPDGSEETG---------------------------------------------------------ERIRNYHKQAFEFISVALQIDEDEK-GDKQK---------------------------------AVQWYRKGIAELEKGIQIQVT-GAGEKADRARK------LQDKMITNLSMAEDRLKLLGNLLSQSPAESSSDDSFYSFSN---GNLRPAPASGAVSKK------------------KDTLTITNQTSLRPKNPPKS-TPNASGLNCTP--------SAAQSSRTGPQNNQKGP---TVKGK---NNVKASTTA--------TASPQRKRDMKN--------------FKNVDSKLASLILNEIVDSGSVVRFDDIAGQDLAKQALQEIVILPALRPELFTGLRAPARGLLLFGPPGNGKTMLAKAVAMESNATFFNISAATLTSKYVGEGEKLVRALFAVARELQPSIIFIDEIDSLLCERR-EGEHDASRRLKTEFLIEFDGVQSGGD------------------ERVLVMGATNRPQELDEAVLRRFAKRIYVALPTEETRLKLLKNLLSKHRNPLSQKELSQLARLTDGYSGSDLTSLAKDAALGPIRELKPEQVRNMSAHEMRDIRISDFLESLKRIKRSVSPQTLDQYVRWNREYGDTTGV", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q8I0P1-1", "uniprot_id": "SPAST_DROME", "id": "Q8I0P1-1", "name": "Spastin", "aln": "--------------------------MVRTKNQSSSSSASSSSTKSPIKSSSGAGSSGGGLGGRQSTHRSSSASNVAAVV----------------------------AGGSSAAGGGSSSNRRSPGSSPDGDDDTTTTDDLTPTTCSPRSGHHHSYGGYSSSVHKQNLYVVSFPIIFLFNVLRSLIYQLFCIFRYLYGASTKVIYRPHRRDCNIEIVVQNSSKEQQQSLNHPSELNREGDGQ--------EQQLSNQPQRFRPIQPLEMAANRPGGGYSPGPGDPLLAKQKHHHRRAFEYISKALKIDEENE-GHKEL---------------------------------AIELYRKGIKELEDGIAVDCWSGRGDVWDRAQR------LHDKMQTNLSMARDRLHFLALREQDLQMQRLSLKEKQKEEAQ--SKPQKTREPMLAGMT------------------NEPMKLRVRSSGYGPKATTSAQPTASGRKLTIGSKRPVNLAVANKSQTLPRNLGSKTSVGAVQRQPAKTAATPPAVRRQFSSGRNTPPQRSRTPINNNGPSGSGASTPVVSVKGVEQKLVQLILDEIVEGGAKVEWTDIAGQDVAKQALQEMVILPSVRPELFTGLRAPAKGLLLFGPPGNGKTLLARAVATECSATFLNISAASLTSKYVGDGEKLVRALFAVARHMQPSIIFIDEVDSLLSERS-SSEHEASRRLKTEFLVEFDGLPGNPDG-----------------DRIVVLAATNRPQELDEAALRRFTKRVYVSLPDEQTRELLLNRLLQKQGSPLDTEALRRLAKITDGYSGSDLTALAKDAALEPIRELNVEQVKCLDISAMRAITEQDFHSSLKRIRRSVAPQSLNSYEKWSQDYGDITI-", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P40328-1", "uniprot_id": "TBP6_YEAST", "id": "P40328-1", "name": "Microtubule severing ATPase YTA6", "aln": "--MAHEKFSIPENFTLAQSLQLLYSVVKNQYKNLADLIINSKGNKDTVTYGKIHKNLDTLLVYVNEGLRKIEKTYT-------------------------LKKGLGNLVVDHPELRSIIED---------------------FQILGQDIRIARRKAETLMAEGNGSPSLSSSSSVLGLGTGNGLRFPKLWRMGSKRDKLKEADEKEAKINKQADNIRRARKLEEEKKLGAKLQYERDLELQ--------REKLIELKVKEKVEFEVAQKLE--------EERVKREEEERKHREQAEKKRISTLKHERKTNYKSRAS---------------------------LDNFSSSSKSSGKIDNSLIKRRSLDVVRTSGERVRTPVR---------KSMEAAEIGMAAQLAWSQYQNGANHSKVSNNGSHSNELQIRYKPTPPLKKRYDYKKPTVN----------------RPIIKSPTLNRQNSKSSRNIPTNSK-LKASKSNTNKVSRRNEQNLEPSSPVLVSATAVPAE---SKPMRSKSGTPDKESSASSSLDSRKE--------------DILKSVQGVDRNACEQILNEILVTDEKVYWEDIAGLRNAKNSLKEAVVYPFLRPDLFKGLREPVRGMLLFGPPGTGKTMIAKAVATESNSTFFSVSASSLLSKYLGESEKLVRALFYMAKKLSPSIIFIDEIDSMLTARS-DNENESSRRIKTELLIQWSSLSSATAQSEDRNN--------TLDSRVLVLGATNLPWAIDDAARRRFSRKLYIPLPDYETRLYHLKRLMAKQKNSLQDLDYELITEMTEGFSGSDLTSLAKEAAMEPIRDLG-DKLMFADFDKIRGIEIKDFQNALLTIKKSVSSESLQKYEEWSSKFGSNGS-", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P39955-1", "uniprot_id": "SAPR1_YEAST", "id": "P39955-1", "name": "Microtubule severing ATPase SAP1", "aln": "MDSQRSHHILTRLTKIRRRPQQPLTDFTELYSRIANETIYYLNLEEKKRYKEALQGWKALTTDVLFKQTLIEHNYPNTQSYTKDEVSLQNGIRELYHKSVMHLKRVKKLVREEPAPRNDMPSSKTYTNHSSSFTRSTEPPPVFQMVPGRMMKTLRNRNACGYKTAYSNPSLSSYGNSTSIKRGEDAENIRVNFVPSKPLSNNASRQHKNPIEHNDPPLKKETELYSDKYISEPILIDLTNDEDDHDVGILKGHNVFDEEESDGFEFDVSDYYDNFSEVDVEEEEEEKEERRRIKTLEAIQQQMSDLSVTSSTSSNKSVSSSENVPGSCIQSLPTTAPALPSLPPPPLLNVDRASSTGALKPHSLETSTTMDSSKIRNPQISKLMKNNHVPYLKGTKSTPTLITKSTPTFITRSKSNTKPIIKSNASSPTSSLTVPNSVIQKPKTAAMAAKRVLNSKKVASNPALNTTKKSHPILKSKTAKVPNSSSKKTSSHPSRPVSNSKPYSHGASQNKKPSKNQTTSMSKTNRKIPAQKKIGSPKIEDVGTEDATEHATSLNEQREEPEIDKKVLREILEDEIIDSLQGVDRQAAKQIFAEIVVHGDEVHWDDIAGLESAKYSLKEAVVYPFLRPDLFRGLREPVRGMLLFGPPGTGKTMLARAVATESHSTFFSISASSLTSKYLGESEKLVRALFAIAKKLSPSIIFVDEIDSIMGSRNNENENESSRRIKNEFLVQWSSLSSAAAGSNKSNTNNSDTNGDEDDTRVLVLAATNLPWSIDEAARRRFVRRQYIPLPEDQTRHVQFKKLLSHQKHTLTESDFDELVKITEGYSGSDITSLAKDAAMGPLRDLG-DKLLETEREMIRPIGLVDFKNSLVYIKPSVSQDGLVKYEKWASQFGSSGS-", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . . . : .* : * . . : . .* : . : . : : . . . * . . : . : . .:.*: : . *: **: . * : **** ** :*:* *: * :**:** *** *.:*:*******.***::*:*** *. :**:.:**::* ***:*:.******** :*:.:.*****:**:**:: * ..*:::***:*.*:*:::..: . *::*:.*** * :*:*. *** :: *:.** :** ::.*: :: .* :..:*:*:****:*:***:**: *:*:* ::: . :* * ** .:* *: **: : * * .* .:*. ", "identical_positions": 123, "similar_positions": 127, "identity": "13.68%" }, { "cls_id": "homologset.agr.MGI:1858898", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9Z2X2-1", "uniprot_id": "PSD10_MOUSE", "id": "Q9Z2X2-1", "name": "26S proteasome non-ATPase regulatory subunit 10", "aln": "MEGCVSNIMICNLAYSGKLDELKERILADKSLATRTDQDSRTALHWACSAGHTEIVEFLLQLGVPVNDK---DDAGWSPLHIAASAGRDEIVKALLVK--GAHVNAVNQNGCTPLHYAASKNRHEIAVMLLEGGANPDAKDHYDATAMHRAAAKGNLKMVHILLFY-KASTNIQDTEGNTPLHLACDEERVEEAKFLVTQGASIYIENKEEKTPLQVAKGGLGLILKRLAESEEASM", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9Z2X3-1", "uniprot_id": "PSD10_RAT", "id": "Q9Z2X3-1", "name": "26S proteasome non-ATPase regulatory subunit 10", "aln": "MEGCVSNLMVCNLAYNGKLDELKESILADKSLATRTDQDSRTALHWACSAGHTEIVEFLLQLGVPVNEK---DDAGWSPLHIAASAGRDEIVKALLIK--GAQVNAVNQNGCTALHYAASKNRHEIAVMLLEGGANPDAKNHYDATAMHRAAAKGNLKMVHILLFY-KASTNIQDTEGNTPLHLACDEERVEEAKLLVTQGASIYIENKEEKTPLQVAKGGLGLILKRIAESEEASM", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O75832-1", "uniprot_id": "PSD10_HUMAN", "id": "O75832-1", "name": "26S proteasome non-ATPase regulatory subunit 10", "aln": "MEGCVSNLMVCNLAYSGKLEELKESILADKSLATRTDQDSRTALHWACSAGHTEIVEFLLQLGVPVNDK---DDAGWSPLHIAASAGRDEIVKALLGK--GAQVNAVNQNGCTPLHYAASKNRHEIAVMLLEGGANPDAKDHYEATAMHRAAAKGNLKMIHILLYY-KASTNIQDTEGNTPLHLACDEERVEEAKLLVSQGASIYIENKEEKTPLQVAKGGLGLILKRMVEG-----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P50086-1", "uniprot_id": "PSD10_YEAST", "id": "P50086-1", "name": "Probable 26S proteasome regulatory subunit p28", "aln": "----MSNYPLHQACMENEFFKVQELLHSKPSLLLQKDQDGRIPLHWSVSFQAHEITSFLLSKMENVNLDDYPDDSGWTPFHIACSVGNLEVVKSLYDRPLKPDLNKITNQGVTCLHLAVGKKWFEVSQFLIENGASVRIKDKFNQIPLHRAASVGSLKLIELLCGLGKSAVNWQDKQGWTPLFHALAEGHGDAAVLLVEKYGAEYD--LVDNKGAKAEDVALNEQVKKFFLNNV---", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :** : : . ..:: :::* : :. ** :.***.* .***: * **..***. ** . **:**:*:***.*.*. *:**:* : ..:* :.::* * ** *..*: .*:: :*:*.**. *:::: .:****: *.**::.:* *::.* **.:* ***. * * : : * :** : .: * ::. :. . .*. :*:: . ", "identical_positions": 71, "similar_positions": 85, "identity": "29.96%" }, { "cls_id": "homologset.agr.MGI:1858899", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q6IFV6-1", "uniprot_id": "Q6IFV6_RAT", "id": "Q6IFV6-1", "name": "", "aln": "MASKCFKASFSSGSLKSPGKAGGGSTRMSRMYSSSSCKLPSPSRGARSFSVCSAGLGRGNYRLSSCLPALCLPTGGFATGYSMGGGWFGEGILTGNEKETMQSLNDRLASYLEKVRQLEQENASLESRIREWCEQQVPYMCPDYQSYFRTMEELQKKTLCSKAENARLVVQIDNAKLAADDFRTKYETEVSLRQLVEADINGLRRILDDLTLCKADLEAQVESLKEELLCLKKNHEEEVNSLRCQLGDRLNVEVDAAPPVDLNRVLDEMRCQYETLVENNRRDAEDWYDTQTEELNQQVVTSSEQLQSCQSDIIELRRTVNSLEIELQAQQSMRDALDSTLAETEARYSSQLAQMQCLIGSVESQLGEIRADLERQNQEYQVLLDVRARLECEINTYRGLLESEDSKLPCNPCAPDYSPSKSCLPCLPAVSCSTGAARTTCSPRPVCVPCPGGRF", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q497I4-1", "uniprot_id": "KRT35_MOUSE", "id": "Q497I4-1", "name": "Keratin, type I cuticular Ha5", "aln": "MASKCLKASFSSGSLKSPGKAGGGSTRVSNMYSSSSCKLPSPSRGARSFSVCSAGLGRGNYRVSSCLPALCLPTGGFATSYGTGGGWFGEGILTGNEKETMQSLNDRLASYLEKVRQLEQENASLESRIREWCEQQVPYMCPDYQSYFRTMEELQKKTLCSKAENARLVVQIDNAKLAADDFRTKYETEVSLRQLVEADINGLRRILDDLTLCKADLEAQVESLKEELLCLKKNHEEEVNSLRCQLGDRLNVEVDAAPPVDLNRVLDEMRCQYETLVENNRRDAEDWYDTQTEELNQQVVSSSEQLQSCQSDIIELRRTVNSLEIELQAQQSMRDALDSTLAETEGRYSSQLAQMQCMIGNVESQLGEIRADLERQNQEYQVLLDVRARLECEINTYRGLLESEDSKLPCNPCAPDYSSSKSCLPCLPAVSCSTGAARTTCSPRPVCVPCPGGRF", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q92764-1", "uniprot_id": "KRT35_HUMAN", "id": "Q92764-1", "name": "Keratin, type I cuticular Ha5", "aln": "MASKCLKAGFSSGSLKSPGGASGGSTRVSAMYSSSSCKLPSLSPVARSFSACSVGLGRSSYRATSCLPALCLPAGGFATSYSGGGGWFGEGILTGNEKETMQSLNDRLAGYLEKVRQLEQENASLESRIREWCEQQVPYMCPDYQSYFRTIEELQKKTLCSKAENARLVVEIDNAKLAADDFRTKYETEVSLRQLVESDINGLRRILDDLTLCKSDLEAQVESLKEELLCLKKNHEEEVNSLRCQLGDRLNVEVDAAPPVDLNRVLEEMRCQYETLVENNRRDAEDWLDTQSEELNQQVVSSSEQLQSCQAEIIELRRTVNALEIELQAQHSMRDALESTLAETEARYSSQLAQMQCMITNVEAQLAEIRADLERQNQEYQVLLDVRARLECEINTYRGLLESEDSKLPCNPCAPDYSPSKSCLPCLPAASCGPSAARTNCSPRPICVPCPGGRF", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*****:**.********** *.*****:* *********** * *****.**.****..** :*********:*****.*. **************************.****************************************:*******************:**************************:****************:***************************************************:******************** ***:********:*********::*********:********:******:*******.***********:* .**:**.***************************************************.**********.**...****.*****:*********", "identical_positions": 409, "similar_positions": 37, "identity": "89.89%" }, { "cls_id": "homologset.agr.MGI:1858901", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q6EV76-1", "uniprot_id": "FUT8_RAT", "id": "Q6EV76-1", "name": "Alpha-(1,6)-fucosyltransferase", "aln": "-------MRAWTGSWR-WIMLILFAWGTLLFYIGGHLVRDNDHPDH-----SSRELSKILAKLERLKQQNEDLRRMAESLR------------------------------IPEGPIDQGTATGRVRVLEEQLVKAKEQIENYKKQA-RNGLGKDHELLRRRIENGAKELWFFLQSELKKLKHLEGN-----ELQRHADEILLDLGHHERSIMTDLYYLSQTDGAGDWREKEAKDLTELVQRRITYLQNPKDCSKARKLVCNINKGCGYGCQLHHVVYCFMIAYGTQRTLILESQNWRYATGGWETVFRPVSETCTDRSGLSTGHWSGEVNDKNIQVVELPIVDSLHPRPPYLPLAVPEDLADRLVRVHGDPAVWWVSQFVKYLIRPQPWLEKEIEEATKKLGFKHPVIGVHVRRTDKVGTEAAFHPIEEYMVHVEEHFQLLARRMQVDKKRVYLATDDPALLKEAKTKYSNYEFISDNSISWSAGLHNRYTENSLRGVILDIHFLSQADFLVCTFSSQVCRVAYEIMQTLHPDASANFHSLDDIYYFGGQNAHNQIAVYPHKPRTDEEIPMEPGDIIGVAGNHWDGYSKGVNRKLGKTGLYPSYKVREKIETVKYPTYPEAEK----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9WTS2-1", "uniprot_id": "FUT8_MOUSE", "id": "Q9WTS2-1", "name": "Alpha-(1,6)-fucosyltransferase", "aln": "-------MRAWTGSWR-WIMLILFAWGTLLFYIGGHLVRDNDHPDH-----SSRELSKILAKLERLKQQNEDLRRMAESLR------------------------------IPEGPIDQGTATGRVRVLEEQLVKAKEQIENYKKQA-RNGLGKDHEILRRRIENGAKELWFFLQSELKKLKHLEGN-----ELQRHADEILLDLGHHERSIMTDLYYLSQTDGAGDWREKEAKDLTELVQRRITYLQNPKDCSKARKLVCNINKGCGYGCQLHHVVYCFMIAYGTQRTLILESQNWRYATGGWETVFRPVSETCTDRSGLSTGHWSGEVNDKNIQVVELPIVDSLHPRPPYLPLAVPEDLADRLLRVHGDPAVWWVSQFVKYLIRPQPWLEKEIEEATKKLGFKHPVIGVHVRRTDKVGTEAAFHPIEEYMVHVEEHFQLLARRMQVDKKRVYLATDDPTLLKEAKTKYSNYEFISDNSISWSAGLHNRYTENSLRGVILDIHFLSQADFLVCTFSSQVCRVAYEIMQTLHPDASANFHSLDDIYYFGGQNAHNQIAVYPHKPRTEEEIPMEPGDIIGVAGNHWDGYSKGINRKLGKTGLYPSYKVREKIETVKYPTYPEAEK----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9BYC5-1", "uniprot_id": "FUT8_HUMAN", "id": "Q9BYC5-1", "name": "Alpha-(1,6)-fucosyltransferase", "aln": "-------MRPWTGSWR-WIMLILFAWGTLLFYIGGHLVRDNDHPDH-----SSRELSKILAKLERLKQQNEDLRRMAESLR------------------------------IPEGPIDQGPAIGRVRVLEEQLVKAKEQIENYKKQT-RNGLGKDHEILRRRIENGAKELWFFLQSELKKLKNLEGN-----ELQRHADEFLLDLGHHERSIMTDLYYLSQTDGAGDWREKEAKDLTELVQRRITYLQNPKDCSKAKKLVCNINKGCGYGCQLHHVVYCFMIAYGTQRTLILESQNWRYATGGWETVFRPVSETCTDRSGISTGHWSGEVKDKNVQVVELPIVDSLHPRPPYLPLAVPEDLADRLVRVHGDPAVWWVSQFVKYLIRPQPWLEKEIEEATKKLGFKHPVIGVHVRRTDKVGTEAAFHPIEEYMVHVEEHFQLLARRMQVDKKRVYLATDDPSLLKEAKTKYPNYEFISDNSISWSAGLHNRYTENSLRGVILDIHFLSQADFLVCTFSSQVCRVAYEIMQTLHPDASANFHSLDDIYYFGGQNAHNQIAIYAHQPRTADEIPMEPGDIIGVAGNHWDGYSKGVNRKLGRTGLYPSYKVREKIETVKYPTYPEAEK----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M2BLI2-1", "uniprot_id": "A0A8M2BLI2_DANRE", "id": "A0A8M2BLI2-1", "name": "Alpha-(1,6)-fucosyltransferase", "aln": "-------MRPWTGSWR-WIALVLLAWGTLLFYIGGHLVKDSEHAPR-----SSRELAKILTKLERLKQQNEDLRRMAQSLR------------------------------IPEGQSDGPISSGRLRSLEEQLSRAKQKIQSFQRLSGEAGPGREQEELRRKVENGVRELWYFIHSEIQKLSHVNPT-----DRQKQTDALLQDLGHQQRAIMTDLHELAQADGAGEWRDKEARDLSILVQNRISFLQNPQDCSKARKLVCNINKGCGYGCQLHHVVYCFMIAYGTQRVLILESHNWRYAPKGWETVFKAVSETCTDRSGATTGHWSGEAHDRDVQVVELPIVDSLHPRPPYLPLAVPEDLAPRLQRLHGDPSVWWVSQFVKFLVRPQAWLEKEIQETCLKLGFKHPIIGVHVRRTDKVGTEAAFHPIEEYMVHVEEQFQSMAQRGHVDKKRVYLATDDPALLQEAKTKYTDYEFISDNSISWSASLHNRYTENSLRGVILDIHFLSQTDFLVCTFSSQVCRVAYEMMQTLHPDASSFFRSLDDIYYFGGQNAHNQIAIYPHQPRTAEDIPLDPGDVIGVAGNHWDGNSKGINRKLGRTGLYPSYKVKEKIETVKYPTYPEADKMLSS", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VYV5-1", "uniprot_id": "FUT8_DROME", "id": "Q9VYV5-1", "name": "Alpha-(1,6)-fucosyltransferase", "aln": "MLLVRQLFGASANSWARALIIFVLAWIGLVYVFVVKLTNTQGQQAAGESELNARRISQALQMLEHTRQRNEELKQLIDELMSDQLDKQSAMKLVQRLENDALNPKLAPEVAGPEPESMFESAPADLRGWNNVAEGAPNDLEAGVPDHGEFEPSLEYEFTRRRIQTNIGEIWNFFSSELGKVRKAVAAGHASADLEESINQVLLQGAEHKRSLLSDMERMRQSDGYEAWRHKEARDLSDLVQRRLHHLQNPSDCQNARKLVCKLNKGCGYGCQLHHVVYCFIVAYATERTLILKSRGWRYHKGGWEEVFQPVSNSCHDAGTANTYNWPGKP---NTQVLVLPIIDSLMPRPPYLPLAVPEDLAPRLKRLHGDPIVWWVGQFLKYLLRPQPTTRDFLTSGMRNLGWERPIVGVHVRRTDKVGTEAACHSVEEYMTYVEDYYRTLEVNGSTVARRIFLASDDAQVIEEARRKYPQYQIIGDPEVARMASVSTRYTDTALNGIILDIHLLSMSDHLVCTFSSQVCRVAYEIMQTMYPDAAHRFKSLDDIYYYGGQNAHNRRVVIAHKPRTHEDLQLRVGDLVSVAGNHWDGNSKGKNTRTNQGGLFPSFKVEEKVDTAKLPLYAGI------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . :.** : :.::** *:: : :*.. . : .:*.::: * **: :*:**:*::: :.* ** : . :* :: * :.:: . . : * **:::.. *:* *: **: *: : : :. : .* : ..::*::::*: : *:** **.***:**: ***.*: .****.**.:*:****::*****************::**.*:*.***:*:.*** *** **:.**::* * . .* :*.*: : **: ***:*** *************** ** *:**** ****.**:*:*:***. .. : . :**:::*::*************** *.:****.:**: :: : . . :*::**:**. :::**: **.:*::*.* .:: *.: .***:.:*.*:*****:** :*.***************:***::***: *:*******:*******: .: .*:*** ::: : **::.******** *** * : .: **:**:**.**::*.* * *. ", "identical_positions": 254, "similar_positions": 185, "identity": "40.45%" }, { "cls_id": "homologset.agr.MGI:1858907", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P62952-1", "uniprot_id": "BLCAP_HUMAN", "id": "P62952-1", "name": "Apoptosis inducing factor BLCAP", "aln": "MYCLQWLLPVLLIPKPLNPALWFSHSMFMGFYLLSFLLERKPCTICALVFLAALFLICYSCWGNCFLYHCSDSPLPESAHDPGVVGT", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P62951-1", "uniprot_id": "BLCAP_MOUSE", "id": "P62951-1", "name": "Apoptosis inducing factor BLCAP", "aln": "MYCLQWLLPVLLIPKPLNPALWFSHSMFMGFYLLSFLLERKPCTICALVFLAALFLICYSCWGNCFLYHCSDSPLPESAHDPGVVGT", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P62950-1", "uniprot_id": "BLCAP_RAT", "id": "P62950-1", "name": "Apoptosis inducing factor BLCAP", "aln": "MYCLQWLLPVLLIPKPLNPALWFSHSMFMGFYLLSFLLERKPCTICALVFLAALFLICYSCWGNCFLYHCSDSPLPESAHDPGVVGT", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9IB61-1", "uniprot_id": "BLCAP_DANRE", "id": "Q9IB61-1", "name": "Apoptosis inducing factor BLCAP", "aln": "MYCLQWLLPVLLIPKPLNPALWFNHSMFMGFYLLSFLLERKPCTICALVFLAALFLICYSCWGNCFLYHCHDSPLPDSAHDPSIVGT", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9V3L0-1", "uniprot_id": "Q9V3L0_DROME", "id": "Q9V3L0-1", "name": "", "aln": "MYCLQCLLPVLLIPKPSNPALMETHVMFIVLYLVGFFLERKPCTICSLVFLTAVSLICYSGVGNCIFWGNCEGHQCENG--------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "***** ********** **** .* **: :**:.*:*********:****:*: ***** ***::: :. :.. ", "identical_positions": 47, "similar_positions": 17, "identity": "54.02%" }, { "cls_id": "homologset.agr.MGI:1858910", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q6AYK2-1", "uniprot_id": "JMJD6_RAT", "id": "Q6AYK2-1", "name": "Bifunctional arginine demethylase and lysyl-hydroxylase JMJD6", "aln": "------MNHKSKKRIREAKRSARPELKDSLDWTRHNYYESYPLSPAAVPDNVERADALQLSVKEFVERYERPYKPVVLLNAQEGWSAQEKWTLERLKRKYRNQKFKCGEDNDGYSVKMKMKYYIEYMESTRDDSPLYIFDSSYGEHPKRRKLLEDYKVPKFFTDDLFQYAGEKRRPPYRWFVMGPPRSGTGIHIDPLGTSAWNALVQGHKRWCLFPTNTPRELIKVTREEGGNQQDEAITWFNVIYPRTQLPTWPPEFKPLEILQKPGETVFVPGGWWHVVLNLDTTIAITQNFASSTNFPVVWHKTVRGRPKLSRKWYRILKQEHPELAVLADAVDLQESTGIASDSSSDSSSSSSSSSSDSDSECESGSEGDGTTHRRKKRRTCSMVGNGDTTSQDDCVSKERSSSR-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9ERI5-1", "uniprot_id": "JMJD6_MOUSE", "id": "Q9ERI5-1", "name": "Bifunctional arginine demethylase and lysyl-hydroxylase JMJD6", "aln": "------MNHKSKKRIREAKRSARPELKDSLDWTRHNYYESYPLNPAAVPDNVERADALQLSVKEFVERYERPYKPVVLLNAQEGWSAQEKWTLERLKRKYRNQKFKCGEDNDGYSVKMKMKYYIEYMESTRDDSPLYIFDSSYGEHPKRRKLLEDYKVPKFFTDDLFQYAGEKRRPPYRWFVMGPPRSGTGIHIDPLGTSAWNALVQGHKRWCLFPTNTPRELIKVTREEGGNQQDEAITWFNVIYPRTQLPTWPPEFKPLEILQKPGETVFVPGGWWHVVLNLDTTIAITQNFASSTNFPVVWHKTVRGRPKLSRKWYRILKQEHPELAVLADAVDLQESTGIASDSSSDSSSSSSSSSSDSDSECESGSEGDGTTHRRKKRRTCSMVGNGDTTSQDDCVSKERSSSR-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6NYC1-1", "uniprot_id": "JMJD6_HUMAN", "id": "Q6NYC1-1", "name": "Bifunctional arginine demethylase and lysyl-hydroxylase JMJD6", "aln": "------MNHKSKKRIREAKRSARPELKDSLDWTRHNYYESFSLSPAAVADNVERADALQLSVEEFVERYERPYKPVVLLNAQEGWSAQEKWTLERLKRKYRNQKFKCGEDNDGYSVKMKMKYYIEYMESTRDDSPLYIFDSSYGEHPKRRKLLEDYKVPKFFTDDLFQYAGEKRRPPYRWFVMGPPRSGTGIHIDPLGTSAWNALVQGHKRWCLFPTSTPRELIKVTRDEGGNQQDEAITWFNVIYPRTQLPTWPPEFKPLEILQKPGETVFVPGGWWHVVLNLDTTIAITQNFASSTNFPVVWHKTVRGRPKLSRKWYRILKQEHPELAVLADSVDLQESTGIASDSSSDSSSSSSSSSSDSDSECESGSEGDGTVHRRKKRRTCSMVGNGDTTSQDDCVSKERSSSR-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6PFM0-1", "uniprot_id": "JMJD6_DANRE", "id": "Q6PFM0-1", "name": "Bifunctional arginine demethylase and lysyl-hydroxylase JMJD6", "aln": "------MNHKSKKRIKEAKRSARPELKDSSDWTKHEYCKSFDLSHRSVKDNVERADVQRLSPEEFIQRFEKPYKPVVLLNVEDSWPAREKWTLERLKRKYRNQKFKCGEDNDGYSVKMKMKYYVEYLESTHDDSPLYIFDSSFGEHAKRRKLLEDYQVPLFFRDDLFQFAGEKRRPPYRWFVMGPARSGTGIHIDPLGTSAWNALVQGHKRWCLFPTHTPRELIKVTRDEGGNQQDEAITWFNVIYPRTQQSTWPDEFRPLEILQRPGETVFVPGGWWHVVLNLDTTIAVTQNFASTTNFPIVWHKTVRGRPKLSRKWYRILKQERPDIAAIADKVDLQESTGIASDSSSDSSSSSSSSSSDSDSEADSGSEGDAMTHRRKKRRTGGMMGNGDITSQDDCASKERSSSR-", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VD28-1", "uniprot_id": "JMJD6_DROME", "id": "Q9VD28-1", "name": "Bifunctional arginine demethylase and lysyl-hydroxylase JMJD6", "aln": "MSEEFKLPKRSRKRTREVKRKARPELDGENAWSAMRYCEKFEP-FWDFTDNLERIEESQVPESEFIERFERPYKPVVIRGCTDGWLALEKWTLARLAKKYRNQKFKCGEDNEGYSVKMKMKYYVEYMQSTRDDSPLYIFDSSFGEHHRRRKLLDDYVVPKYFRDDLFQYCGENRRPPYRWFVMGPARSGTGIHIDPLGTSAWNTLIRGHKRWCLFPTQTPKELLKVTSAMGGKQRDEAITWFSTIYPRTQLPSWPEQYRPIEVLQGAGETVFVPGGWWHVVLNMDDTIAITQNFSSQTNFPCVWHKTVRGRPKLSRKWLRVLRDQRPELAQIADSINLNESTGFASDSSSNSSSSSSSSSSSSE-EEESDDGGDSNTDSGQESLTAKKKKKRRMAGGGSGSGSMGGSSRS", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : ::*:** :*.**.*****... *: .* :.: . **:** : ::. .**::*:*:******: . :.* * ***** ** :*************:***********:**::**:***********:*** :*****:** ** :* *****:.**:************.*****************:*::********** **:**:*** **:*:*******..****** .:** :::*:*:** .****************:* ***:****:* **** **************** *:*::::*::* :** ::*:****:******:**********.*: * :*.. **. .. :: * : :. .. .. .*** ", "identical_positions": 245, "similar_positions": 95, "identity": "59.76%" }, { "cls_id": "homologset.agr.MGI:1858916", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q5EB96-1", "uniprot_id": "SEPT1_RAT", "id": "Q5EB96-1", "name": "Septin-1", "aln": "--------------------------------------------------------------------------MDKE--------------------YVGFAALPNQLHRKSVKKGFDFTLMVAGESGLGKSTLINSLFLTNLYEDRQVPDASARTTQT---------------------LTIERRGVEIEEGGIKVKLTLVDTPGFGDSVDCS-DCWLPVVRFIEEQFEQYLRDESGLNRKNIQDSRVHCCLYFISPFGRGLRPLDVAFLRAVHEKVNIIPVIGKADALLPRETQVLKQKIRDQLKEEEINIYQFPECDSDEDEEFKKQNEEMKENIPFAVVGSSEVVREG-TRPVRGRRYSWGTVEVENPHHCDFLNLRRMLVQTHLQDLKEVTHDLLYEGYRARCLQSL---------------ARPGARDRASRSKLSRQSATEIPLPMLPLADTEKLIRE-KDEELRRMQEMLEKMQAQMQQSQAQGEQ-SDVL---------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P42209-1", "uniprot_id": "SEPT1_MOUSE", "id": "P42209-1", "name": "Septin-1", "aln": "--------------------------------------------------------------------------MDKE--------------------YVGFAALPNQLHRKSVKKGFDFTLMVAGESGLGKSTLINSLFLTNLYEDRQVPDASARTAQT---------------------LTIERRGVEIEEGGIKVKLTLVDTPGFGDSVDCS-DCWLPVVRFIEEQFEQYLRDESGLNRKNIQDSRVHCCLYFISPFGRGLRPLDVAFLRAVHEKVNIIPVIGKADALMPRETQALKQKIRDQLKEEEINIYQFPECDSDEDEEFKKQNEEMKENIPFAVVGSCEVVRDG-TRPVRGRRYSWGTVEVENPHHCDFLNLRRMLVQTHLQDLKEVTHDLLYEGYRARCLQSL---------------ARPGARDRASRSKLSRQSATEIPLPMLPLADTEKLIRE-KDEELRRMQEMLEKMQAQMQQSQAQGEQ-SDVL---------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8WYJ6-1", "uniprot_id": "SEPT1_HUMAN", "id": "Q8WYJ6-1", "name": "Septin-1", "aln": "---------------------------------------------------------------------MAGGVMDKE--------------------YVGFAALPNQLHRKSVKKGFDFTLMVAGESGLGKSTLINSLFLTNLYEDRQVPEASARLTQT---------------------LAIERRGVEIEEGGVKVKLTLVDTPGFGDSVDCS-DCWLPVVKFIEEQFEQYLRDESGLNRKNIQDSRVHCCLYFISPFGRGLRPLDVAFLRAVHEKVNIIPVIGKADALMPQETQALKQKIRDQLKEEEIHIYQFPECDSDEDEDFKRQDAEMKESIPFAVVGSCEVVRDGGNRPVRGRRYSWGTVEVENPHHCDFLNLRRMLVQTHLQDLKEVTHDLLYEGYRARCLQSL---------------ARPGARDRASRSKLSRQSATEIPLPMLPLADTEKLIRE-KDEELRRMQEMLEKMQAQMQQSQAQGEQ-SDAL---------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q0KHR7-1", "uniprot_id": "Q0KHR7_DROME", "id": "Q0KHR7-1", "name": "Septin", "aln": "---------MKHQPPPPPLPLSQPPTMGATAAG----GVASVIST-MNGSSSSGIEAVKCRPPIYPKPKTPSFDKDRD--------------------YIGFATLPEQVHRKSVKRGFEFTLMVVGESGLGKSTLINSLFLGDLYKNRQMPNVEERIEKT---------------------TKVEKKTMDIEERGVRLRLTVVDTPGFGDAINCE-DSWRVCTQYIDEQFRQYFTDESGLNRRNIQDNRVHCCLYFVPPWGHSLRQMDLDLIRRLHRKVNIVLVIGKADCLNKQEVRKLKERILQDLEDNHIQLYQFPECDSDEDDDFKQQDRELKASIPFAVVGSNTILEVA-GKKVRGRQYPWGVVNVEDPEHSDFIKLRTFLISTHMQDLKDTTQDVHYENFRAQCISQI---------------SQHALRERG---KLKRDSISSTNGFDAAISETDRLLLQ-KDEEIRRMQDMLTQMQEKLKQTHLMEMKKNDSVIDV------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P32457-1", "uniprot_id": "CDC3_YEAST", "id": "P32457-1", "name": "Cell division control protein 3", "aln": "MSLKEEQVSIKQDPEQEERQHDQFNDVQIKQESQDHDGVDSQYTNGTQNDDSERFEAAESDVKVEPGLGMGITSSQSEKGQVLPDQPEIKFIRRQINGYVGFANLPKQWHRRSIKNGFSFNLLCVGPDGIGKTTLMKTLFNNDDIEANLVKDYEEELANDQEEEEGQGEGHENQSQEQRHKVKIKSYESVIEENGVKLNLNVIDTEGFGDFLNNDQKSWDPIIKEIDSRFDQYLDAENKINRHSINDKRIHACLYFIEPTGHYLKPLDLKFMQSVYEKCNLIPVIAKSDILTDEEILSFKKTIMNQLIQSNIELFKPPIYSND-DAENSHLSERLFSSLPYAVIGSNDIVENYSGNQVRGRSYPWGVIEVDNDNHSDFNLLKNLLIKQFMEELKERTSKILYENYRSSKLAKLGIKQDNSVFKEFDPISKQQEEKTLHEAKLAKLEIEMKTVFQQKVSEKEKKLQKSETELFARHKEMKEKLTKQLKALEDKKKQLELSINSASPNVNHSPVPTKKKGFLR", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : *:*** **:* **:*:*.**.*.*: .* .*:**:**:::** : : . : : . . : :: *** *:::.*.::** **** :: . ..* : *:.:* **: *. :**:.*:*.*:*.****: * *: *: :*: ::: ::.* *:: **.*:* * .* :*: * ::* :..*.::: * ..* * : .: . .: .:*:**:** ::. . **** *.**.::*:: .*.** *: :*:. .:::**: * .: **.:*: : .: :: .. ** : . :::.:: : : : * : * ::* :: ::: . : . : ", "identical_positions": 98, "similar_positions": 147, "identity": "18.81%" }, { "cls_id": "homologset.agr.MGI:1858943", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q7TMZ5-1", "uniprot_id": "Q7TMZ5_RAT", "id": "Q7TMZ5-1", "name": "", "aln": "MAEGDNRSSNLLAVETASLEEQLQGWGEVMLMADKVLRWERAWFPPAIMGVVSLLFLIIYYLDPSVLSGVSCFVMFLCLADYLVPILAPRIFGSNKWTTEQQQRFHEICSNLVKTRRRAVGWWKRLFTLKEEKPKMYFMTMIISLAAVAWVGQQVHNLLLTYLIVTFVLLLPGLNQHGIILKYIGMAKREINKLLKQKEKKNE", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9JKW0-1", "uniprot_id": "AR6P1_MOUSE", "id": "Q9JKW0-1", "name": "ADP-ribosylation factor-like protein 6-interacting protein 1", "aln": "MAEGDNRSSNLLAVETASLEEQLQGWGEVMLMADKVLRWERAWFPPAIMGVVSLLFLIIYYLDPSVLSGVSCFVMFLCLADYLVPILAPRIFGSNKWTTEQQQRFHEICSNLVKTRRRAVGWWKRLFSLKEEKPKMYFMTMIISLAAVAWVGQQVHNLLLTYLIVTFVLLLPGLNQHGIILKYIGMAKREINKLLKQKEKKNE", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q15041-1", "uniprot_id": "AR6P1_HUMAN", "id": "Q15041-1", "name": "ADP-ribosylation factor-like protein 6-interacting protein 1", "aln": "MAEGDNRSTNLLAAETASLEEQLQGWGEVMLMADKVLRWERAWFPPAIMGVVSLVFLIIYYLDPSVLSGVSCFVMFLCLADYLVPILAPRIFGSNKWTTEQQQRFHEICSNLVKTRRRAVGWWKRLFTLKEEKPKMYFMTMIVSLAAVAWVGQQVHNLLLTYLIVTSLLLLPGLNQHGIILKYIGMAKREINKLLKQKEKKNE", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VES1-1", "uniprot_id": "AR6P1_DROME", "id": "Q9VES1-1", "name": "ADP-ribosylation factor-like protein 6-interacting protein 1", "aln": "MAASQVDQKRALN----KLKHDLEPFRTAIVGAYGVLTWEKQYYAGVVFGVISCLYLVLWYLDLSLITLLSLLGVISILLNYAFPMVSRLIFGGVNWDGDQEAKFEDVCGQVCAVKGSLVVWYEYLFNER--KSTVFVIVMSLGLLAMAWIGAIINNLLLMYLATLLILMWPGLQNKDIFKAITQRASKIINEKIQCGKRKLQ", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "** .: ... * .*:.:*: : .:: * ** **: ::. .::**:* ::*:::*** *::: :* : :: * :* .*::: ***. :* :*: :*.::*.:: .: * *:: **. : *..::.:.* :.* *:**:* ::**** ** . :*: ***:::.*: *.: **: :: ::* :", "identical_positions": 55, "similar_positions": 85, "identity": "27.09%" }, { "cls_id": "homologset.agr.MGI:1858952", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "E9PT59-1", "uniprot_id": "E9PT59_RAT", "id": "E9PT59-1", "name": "", "aln": "MEAEEPEHGACTPVPDIEELGAIPEGIMRSSQIPALDPEAQEGQDPSYKWTDGHRSLMDQSKVLRDVSDHTPNSVAIFFKKDSSAMATSQEILLAEARDTADQQEAVTQSLQDRLSTTVAAPELLGCAVQEEWLDIP---SKLDS-RVEAELQPELMSLTLAVSKEKEEEESSPDTSTP-GFWPPSKIHPGETDQTEGSGMELLRQGKQLQLEATQENRGQQGLLQPQEAQGLEEQEGQEVEIQEEGTLREDICFGGLLGEQKEVEEDFNDN-KEEQKQEQIQSYMLLGGQWESEGLSGELEGLNYNERSQEERERRVCGQRDSKE-EGQDQELREVEERRVGTQCAENQMLEEISENVRRRQEDHDQAGQAMHVGDQKEVVDSGDREQGTWDSGGQAAEERSRTGEDNKPCLPMTSIAPGVLSPGTLFPAIPSSVDDMSQIQREPVPEELTTQAPTPAPEPTEWSHQHISPPASFATEEALDN-RTHDSQQEEFKLRKGTISNQGTENVSASISVAPSGTPDLPPFTPPNVFPTTATFSLVSSSVILPEKETPAASISADISPHYGPCETPPLPAKSTRDPCAT----SDTANPHSPLTSYTGVTQHLRSNSFPGSHRTEQTPDSMGMSLSFSHLELPQRPP--KTAIYGSLIPRRNRRS-RDGVVFSESSAALFALKQDSEEFTSNPESSSNPHGSQPWGSPQNSAFAIGSPVNVSSPPTVSMDM--IHEALPPPPPEKRHSYSHIVERDGLFHEVAATLKRHSHPPPLTLSSGLHRSPKGSFSLVPDSVVARQHRPLPSTPEGSHHTQTSIPSRLRYNKPLPPTPDMPEPCHSSISSSNISRIYRPLPPVPITDPSSEPPPLPPKSRERSRSVQVGVMHSMGQANPRTTGQDWTVST-LSVGRTSWPPATGRSTESLPPTSRCNSEVSPGLAFSNMTNLLSPSSPTTPWSPELQIPTSKDESGLTEESAPPVRGSFRRPALQEEFNNTRRSALGSRKKSEKPIHYQLEKASSWPHRRDTARTS-ESSSEQVVLGQAPNKQKGWNRQGLRRPSILPESSSDLRNPAAGRLPGSSDSVVFREKKPKEGMGGFSRRCSKLINSSQLLYQEYSDVVLNKEIQSQQRLDSLAEPPGISSPRYRRKALVSSDSYLQRLSMASSGSLWQEIPVVRNSTVLLSMTHEDQKLQEAKFELIVSEASYLRSLNIAVDHFQHSTQLRATLSNQDHQWLFSRLQDVRDVSTTFLSDLEENFENNIFSFQVCDVVLDHAPDFHRVYLPYVTNQTYQERTFQSLMNSNSSFREVLEKLESDPVCQRLSLKSFLILPFQRITRLKLLLQNILKRTQPGSSEEAEATKAHHALEKLIRDCNSNVQRMRRTEELIYLSQKIEFECKIFPLISQSRWLVKSGELTALEFSVSPGLKRKLTTRPVHLHLFNDCLLLSRPREGSRFLVFDHAPFSSIRGEKCEMKLHGAHKNLFRLFLLHNAQGTQAEFLFRTETQSEKLRWISALAMPREELDLLECYDSPQVQCLRAYKPRENDELALEKADVVMVTQQSSDGWLEGVRLSDGEQGWFPLQQVEFISNPEVRVQNLKEAHRVKTAKLQLVEQQV", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "E9Q7D5-1", "uniprot_id": "ARHG5_MOUSE", "id": "E9Q7D5-1", "name": "Rho guanine nucleotide exchange factor 5", "aln": "MEAEEPEYGVSTEVPDIEELKTIPEGIMRSSQIPALDPEAQEDRDPSYKWTDGHRPVMNQSKVLRDMGDHTPNSMAIFFKKESSDMETSQEILLAEACNTPDQQEAVIQSLKDRLSRTIAAPELLACAVQEEWLDIP---SKLDN-RVGAELQSELMSLTLAVSKEKEEEETSPDTSIPRGSWPPCKTHPGETEQTQGSGSELLRQGKQLQLEATQENQGQEGFLQSQEAQGLEEQEGQEVEIQEEGTLNEGICFGGLLGEQEEVEEGFNGN-EEEQKQGQIQSYMLLGGQWENEGLSGELEGLNYSERGQENRERRVWVLRDSEE-EGQDQESREVEERRVATQYTENQRLVEKSEIVKRKQRDHDQTGKVMPVRDQKEVVDSGDRVQGNGDSGGQTAVEGSRPGEDSKPSLPVASVDPEVLSPGTLFPGISSSVADIPQIQKEPVCEELSPQAP--ALEPTEWSHQPISPPASFAPEESLDN-RTHNSQQEEFRLRKG------IEVVSASTSVAPSGTRDSPPFSPPNVFSSTATLSPVSSSVILP-EETPTASASADTPHHCGPCETPPLPAKSSRYPCAT----SDTANPHSPLSSYTGVTQHLRSNSFPGSHRTEQTPDSLGMSLSFSHLELPQRPP--KPAIYGSLTPRRNRRS-RDGIVFSDSSTALFALKQDSEEFTSNPERPSSPHGSPTWGSPQNSAFAIGSPANVSSPPTVSMDMT-IREALLPIPPEKRHSYSHIVERDGLLHEVASTLKRHSHPPPLTLSSGLHRSSKGSFSLVPDSTVARQHRPLPSTPESPNHTQTSIPSRLRYNKPLPPTPDMPEFYHPSISSSYISRMYRPLPPVPIIDPSSEPPPLPPKSRGRSKSIQGGVIHSGGQAKPRPNNQDWTAST-LSVGRTSWPPATGRSTESLPLTSRCNNEVSPGLAFSNMTNLLSPSSPTTPWIPDLQRPTTKDESGLTEESEPPVRGSFRRSAPQEEFNNTRRSALGSRKNSEKPLHHQLEKASSWPHRRDPARTS-ESSSEQVVLGQVPNKQKGWNRQGLRRPSILPESSSDLRNPAAGRLPGSSDSVVFREKKPKEGMGGFSRRCSKLISS-QLLYQEYSDVVLNKEIQSQQRLDSLAEPHGLSSPRHRRKALVSSDSYLQRLSMASSGSLWQEIPVVRNSTVLLSMTHEDQKLQEAKFELIVSEASYLRSLNIAVDHFQHSAQLRGTLSNQDHQWLFSRLQDVRDVSTTFLSDLEENFENNIFSFQVCDVVLNHAADFHRVYLPYVTNQTYQERTFQSLMNSNSSFREVLEKLESDPICQRLSLKSFLILPFQRITRLKLLLQNILKRTQPGSSEEAEATKAHHALEKLIRDCNSNVQRMRRTEELIYLSQKIEFECKIFPLISQSRWLVKSGELTALEFSVSPGLRRKLTTRPVHLHLFNDCLLLSRPREGSRFLVFDHAPFSSIRGEKCEMKLHGPHKNLFRLFLLHNAQGTQVEFLFRTETQSEKLRWISALAMPREELDLLECYDSPQVQCLRAYKPRENDELALEKADVVMVTQQSSDGWLEGVRLSDGEQGWFPVQQVEFISNPEVRAQNLKEAHRVKTAKLQLVEQQV", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q12774-1", "uniprot_id": "ARHG5_HUMAN", "id": "Q12774-1", "name": "Rho guanine nucleotide exchange factor 5", "aln": "MEAEEAQRGASPPISAIEEFSIIPEAPMRSSQVSALGLEAQEDEDPSYKWREEHRLSATQQSELRDVCDYAIETMPSFPKEGSADVEPNQESLVAEACDTPEHWEAVPQSLAGRQARTLAPPELWACPIQSEHLDMAPFSSDLGSEEEEVEFWPGLTSLTLGSGQAEEEEETSSDNSGQTRYYSPCEEHPAETNQNEGSESGTIRQGEELPPEELQES---QGLLHPQEVQVLEEQGQQEAGFRGEGTLREDVCADGLLGEEQMIEQVNDEKGEQKQKQEQVQD-VMLGRQGERMGLTGEPEGLNDGEWEQEDMERKAQGQGGPEQGEERKRELQVPEENRADSQDEKSQTFLGKSEEVTGKQEDHGIKEKGVPVSGQ-EAKEPESWDGGRLGAVG-RARSREEENEHHGPSMP-ALIAPEDSPHCDLFPGASYLMTQIPGTQTESRAEELSPAALSPSLEPIRCSHQPISLLGSFLTEESPDKEIDQNSQQEESRLRKGTVSSQGTEVVFASASVTPPRTPDSAPPSPAEAYPITPASVSARPPVAFPRRETSCAARAPETASAPLSMDDPSPCGTSEMCPAALYGFPSTGTSPPRPPANSTGTVQHLRSDSFPGSHRTEQTPDLVGMLLSYSHSELPQRPP--KPAIYSSVTPRRDRRSGRDYSTVSASPTALSTLKQDSQESISNLERPSSPPSIQPWVSPHNPAFATESPAYGSSPSFVSMEDVRIHEPLPPPPPQRRDTHPSVVETDGHARVVVPTLKQHSHPPPLALGSGLHAPHKGPLPQASDPAVARQHRPLPSTPDSSHHAQATP--RWRYNKPLPPTPDLPQPHLPPISAPGSSRIYRPLPPLPIIDPPTEPPPLPPKSRGRSRSTRGGHMNSGGHAKTRPACQDWTVPLPASAGRTSWPPATARSTESFTSTSRSKSEVSPGMAFSNMTNFLCPSSPTTPWTPELQGPTSKDEAGVSEHPEAPAREPLRRTTPQQGASGPGRSPVGQARQPEKPSHLHLEKASSWPHRRDSGRPPGDSSGQAVAPSEGANKHKGWSRQGLRRPSILPEGSSDSRGPAVEKHPGPSDTVVFREKKPKEVMGGFSRRCSKLINSSQLLYQEYSDVVLNKEIQSQQRLESLSETPGPSSPRQPRKALVSSESYLQRLSMASSGSLWQEIPVVRNSTVLLSMTHEDQKLQEVKFELIVSEASYLRSLNIAVDHFQLSTSLRATLSNQEHQWLFSRLQDVRDVSATFLSDLEENFENNIFSFQVCDVVLNHAPDFRRVYLPYVTNQTYQERTFQSLMNSNSNFREVLEKLESDPVCQRLSLKSFLILPFQRITRLKLLLQNILKRTQPGSSEEAEATKAHHALEQLIRDCNNNVQSMRRTEELIYLSQKIEFECKIFPLISQSRWLVKSGELTALEFSASPGLRRKLNTRPVHLHLFNDCLLLSRPREGSRFLVFDHAPFSSIRGEKCEMKLHGPHKNLFRLFLRQNTQGAQAEFLFRTETQSEKLRWISALAMPREELDLLECYNSPQVQCLRAYKPRENDELALEKADVVMVTQQSSDGWLEGVRLSDGERGWFPVQQVEFISNPEVRAQNLKEAHRVKTAKLQLVEQQA", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1RFG0-1", "uniprot_id": "A0A8M1RFG0_DANRE", "id": "A0A8M1RFG0-1", "name": "", "aln": "MDRER------------AMMQDSCDGTRERDRLPAIRRREMDWRE-RERWRDGDQYANGKS------------SLFEHTVHGERDKESKKGDTFPRMTKANRERDRRIPLSENERQRRLGRPKDTTYEDEKEREKRR--YRDMDTRRRMKEHSDKLREQEFELGIRGRRREGHTGTNDPTGMREKETDRERDRYRQRDREVRYYPRPIERETESFSDKE-----WRTERQNGAERSRKRDTKSEGD--------SDGDRGKEMNREAVTKPGHKLYKSEGDSKADQRVDRVREKDRRRDQEVWRYKEMVRPREKDYRETGYYDKNGMRKDKRPDRDAYSNTPERGRYRNAELE-KDGYSEREIEDRERWRRQNREPYRDKMEKSGQRTGGKISGVEIEKEHNRSVGENLEDRNRKNTSESEKEKLKGRTDGEQEVRIAPREEEGRQIVVEETVTKKFTGRIMNRWLEPRREKNPSLLEEDYRDR--ERARERYNQRFKESTKYEEDPARNNESKRTSAKDKYRAGEFMGDIDVESNEKLDKQEDMVNDKEAVEPEWRAKREIGGNNMEVNEREEERSIDRHDYSG----------IEEGSEGESRAEKDRIISADDGFVTVSSGGDIEDCMDFRNGEVPTDISGCSEATQGEEREPLRVFCVIGQTPIESQTKQNPYIDTASEEATDQHSDQNIDIQGVMFIEDANEAFEKFEHKESDIEGAMDDLALSANEEKVEQTGDNDQGTDDITSLKGQMIPSKEGAEEEPAEPSVTLDPCNDDGPETIVAPSEDALHRREMEATGNTEEHFDSDDTWSTCEERKRCSTAPHLTWAKNVVKEILGPNSEDTEHMRGSVTHIDIQINTQTETDREINISR-EHEELIQGEEKEQGEIEKESDEETILLDPSCIEQTVSSKREADRTVEGHVSKRKDSIENVILGSSSFRELGNEARIRRRGIR----KTTEGTKEEEEDEEEGGVGRDRRTRVFNNSDAE--------------EDELCLTWSE------------GDLRKLGRTKKRSSKYFNSQLYQEYSEVVQNREILLTNYDTTSLSGDNITIRSSSP---LNHSPKLSHRPLPALPQVHLHPHSLSLNNSLKSLN-----LPQQSINRPPSPRLSIS-----------ASSPTLWQDLPGVRNSPEIVELTEDERRLQEVRFEVVTSEASYCRSLDIVVENFVLSKQLNAILSSQDKNWLFSRLNDVRAISHSFMSHLEENVERDMLHFTVCDIIIKYCPRFRNVYVPYLTNQSYQDKTYQRLMDESQEFRRVVEKLERNPVCQRLPLRSFLILPFQRITRLKLLVQNIVKRTAPKTKDEVQAIKAMKLLEKMILDSNESISQMKNIESLVTLNAKVDFECRTLPLISQSRRLVREGPVTELRDFS---LKDREEERSVYMHLFNDYLLLSIRKEGGRFTVIDHAPVSELRAENCRFKLHSLQKNLFRLHMP------QKALLLRTDTQADNLRWISALSRPYPEIDFGAVQETPQMQCIRAYVAQQPDELSLEKADVLVVHQQSSDGWVEGTRLSDRQRGWAPELHLETITSDKARKRNLLDTMKIATAAM-------", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*: *. : :. . .::.*: . : .: :* : .: :. :: . . . ..: ... .: . : .. :. *: :.* . .:.. . * * . : . ...* .... : : : .. : : * .:. :.:. : *.. ::. . : .* *:: * . : :.: : : :. * .: .: : : . : . .: : .. .. : . . .*: : : : .. . * .. .*. . . : . * : . . . . *: *: *. : :: : ::::. * .:. . . * . : : . : :. . .:: * * ... * .: . : :.: : *:* . . * .. . . .. .. :. *:* .: . . : . * ** . . :. .* . :. . :.. .* :... *.::*.. . : .. *. *: .. .* : . :: . * . . .* .: * .. . : .:. * :. . . :. *: : ::. : : . :. . . . . . :: *.:: .: : * .: . :.: .. : :: * * .*. . . * . ... . . * . :*.. .: .. :: . : .. * : . : . . ..*.:.:*...* :. .: . : : : :: . .: **:.::* : . . * * :: *** :***::* ****. ::.:*.::::***.:**::.***** ***:*.*::* * .*.. **.*:::******:*** :* :*:*.****.*.::: * ***:::.:.. *:.**:**:***:**::*:* **:....**.*:**** :*:****.*:****************:***:*** * :.:*.:* ** : **::* *.*..:. *:. *.*: *. *::***: :******* **:.* :* *. *: : *.*::***** **** :**.** *:****.*.:*.*:*.:***. :******.: * :*:**:**:::*******: * *:*: ::**:**:*** .:: ***:******::* *******:**.**** ::** * ::* *:. :.* :** :: :: ** : ", "identical_positions": 287, "similar_positions": 487, "identity": "17.85%" }, { "cls_id": "homologset.agr.MGI:1858959", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9VCZ0-1", "uniprot_id": "Q9VCZ0_DROME", "id": "Q9VCZ0-1", "name": "Elongation of very long chain fatty acids protein", "aln": "------------------------------------------------------------------------------------------------------------------------------MSVRLNETTTIVDRMVNFFVEHEDLRTKQWFLSNAPGPLFMILGAYLYFCLYAGPRYMRDRKPFELKNTLLVYNAVQVLLSWVLFYEGYKGGWGG----------------------------HYNFKCQPVTYESDPISMRMARAVWLYYIAKITELLDTVFFVLRKKQRQISFLHLYHHTLMPVCAFIGVKYFAGGHGTLLGFINSFIHIIMYAYYLLSAMGPKVQKYLWWKKYITILQIVQFLIIFVHTLQIQFQPNCNFPK-SIAALLTFNAGLFTYMFSAFYVANYKKEAAAQAKLAAKKE-----------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VCY6-1", "uniprot_id": "Q9VCY6_DROME", "id": "Q9VCY6-1", "name": "Elongation of very long chain fatty acids protein", "aln": "------------------------------------------------------------------------------------------------------------------------------MAAVN---ATQVDYWNFLFTDLADPRTNDWFLIKSPLPLLGILAFYLFFVLSWGPKFMKDRKPFKLERTLLVYNFFQVALSVWMVYEG-VVIWQ-----------------------------YYSWRCQPVDWSRTPKAYREARVVYVYYLAKITELLDTIFFVLRKNDRQVTFLHVYHHTVMPMISWGTSKYYPGGHGTFIGWINSFVHIIMYSYYFLSAFGPQMQKYLWWKKYITNLQMIQFCCAFIHQTQLLYT-DCGYPR-WSVCFTLPNAVFFYFLFNDFYQKSYKKKQAAAKEKALSADNN----------------------------------------NDG--------------------CAKDLNKAIQLQQEKQKAL-----------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VCY5-1", "uniprot_id": "Q9VCY5_DROME", "id": "Q9VCY5-1", "name": "Elongation of very long chain fatty acids protein", "aln": "------------------------------------------------------------------------------------------------MSMNYHNYNSSSRFEMVVEIANIALDEFKTHHITRNYTGLVQRYYQLVEEDYGDPRAKRFPLMEHPMFTFGMVAVYLSWVLVIGPLFMRDRKPFQLRRTLVVYNAFQVALSGYMFYEHLMAGWLN----------------------------YYNLKCQPVDYSDSPSSKRMLNLCYLYYLSKLTEFADTMFFVLRKKSSQITWLHVYHHSVTPLETWVLVKFLAGGNATFPNLLNNFVHVCMYFYYMMAAMGPEYAKFLWWKKYMTELQIAQFVLCIFHTLRALFSNQCQFSK-FISALLLLNASIFFCLFMNFYMQSYRKTKAAQQLQQQQQQQK----------------------------------------QQQQLDATP--------------CKADSNNNTAMLAQKLKAN-----------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VHX7-1", "uniprot_id": "ELOV7_DROME", "id": "Q9VHX7-1", "name": "Very long chain fatty acid elongase 7", "aln": "----------------------------------------------------------------------------------------------------------------------------------MDYLTMFYDGWRDLMDNKSDPRTRDYPLMSSPFPTIAISLTYAYIVKVLGPKLMENRKPFELRKVLIVYNAAQVIFSAWLFYESCIG---------------------------GWLNG-YNLRCEPVNYSYSPKAIRTAEGCWWYYFSKFTEFFDTFFFVMRKRYDQVSTLHVIHHGIMPVSVWWGVKFTPGGHSTFFGFLNTFVHIFMYAYYMLAAMGPKVQKYLWWKKYLTVMQMIQFVLVMVHSFQLFFKNDCNYPI-GFAYFIGAHAVMFYFLFSNFYKRAYVKRDGKDKASVKANGHA--NGHVKALK-----------------------DGDVAPTSNGQANGFHNTFSKFTT----DMCNPALNSSTRQRVLVNAGNK----------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "A0A0B4KF65-1", "uniprot_id": "A0A0B4KF65_DROME", "id": "A0A0B4KF65-1", "name": "Elongation of very long chain fatty acids protein", "aln": "----------------------------------------------------------------------------------------------------------------------------------MALIMKYIDSISRYMDSHSDSRTKGWPMMSSPFPTLAVCLTYVYLVKVLGPRLMENRKPLNLQNTLVMYNAIQVVFSAWLFYECLMGGWWGSYSFRCQPVDYTDSPTSRRIGISGWLTGHYSFRCQPVDYSNNPRTLRMVHACWWYYFSKFTEFMDTIFFVLRKKSSQVTTLHVIHHGCMPMSVWFGVKFTPGGHSTFFGLLNTFVHIVMYTYYMFSAMGPQYQKYLWWKKYLTTLQMVQFILIMVHAFQLLFI-DCNYPK-AFVWWIGMHAVMFFFLFNEFYKAAYRSRMMK-KNGALANGHAKPNGYCKSINAHDDLAMPQTTEATATATPASKANGSSTPPSNGHANGVENVYKQVANGSAHKGSNGGLSNGYATKLLDDASQELKQRKTPK--", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "A0A1B0GWP1-1", "uniprot_id": "A0A1B0GWP1_RAT", "id": "A0A1B0GWP1-1", "name": "Elongation of very long chain fatty acids protein 1", "aln": "MNCVVRRKEGSRRRPGRQSSLEEGGRKGGKGGRQGKVWRGMVGGSLQAGWMLHPNCLFSHIPLLTMARIQLGALGMLGKYFTTELDSQPYPFVSEPSELSDSVSCLFDYMCDGVMHDPCLMPTLHPSLESLARMEAVVNLYQELMKCA-DPRIQNYPLMGSPLLITSILLTYVYFVLSLGPRIMANRKPFQLRGFMIVYNFSLVTLSLYIVYEFLMSGWLS----------------------------TYTWRCDPVDFSNNPEALRMVRVAWLFMLSKVIELMDTVIFILRKKDGQVTFLHVFHHSVLPWSWWWGIKIAPGGMGSFHAMINSSVHVVMYLYYGLSALGPVAQPYLWWKKHMTAIQLIQFVLVSLHISQYYFMPSCNYQYPIIIHLIWMYGTIFFILFSNFWYHSYTKGKRLPR---------------------------------------------------------------------------AVQQNGAAASMKVKAN-----------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9JLJ5-1", "uniprot_id": "ELOV1_MOUSE", "id": "Q9JLJ5-1", "name": "Very long chain fatty acid elongase 1", "aln": "-------------------------------------------------------------------------------------------------------------------------------------MEAVVNLYHELMKHA-DPRIQSYPLMGSPLLITSILLTYVYFILSLGPRIMANRKPFQLRGFMIVYNFSLVILSLYIVYEFLMSGWLS----------------------------TYTWRCDPIDFSNSPEALRMVRVAWLFMLSKVIELMDTVIFILRKKDGQVTFLHVFHHSVLPWSWWWGIKIAPGGMGSFHAMINSSVHVVMYLYYGLSALGPVAQPYLWWKKHMTAIQLIQFVLVSLHISQYYFMPSCNYQYPIIIHLIWMYGTIFFILFSNFWYHSYTKGKRLPR---------------------------------------------------------------------------AVQQNGAPATTKVKAN-----------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9BW60-1", "uniprot_id": "ELOV1_HUMAN", "id": "Q9BW60-1", "name": "Very long chain fatty acid elongase 1", "aln": "-------------------------------------------------------------------------------------------------------------------------------------MEAVVNLYQEVMKHA-DPRIQGYPLMGSPLLMTSILLTYVYFVLSLGPRIMANRKPFQLRGFMIVYNFSLVALSLYIVYEFLMSGWLS----------------------------TYTWRCDPVDYSNSPEALRMVRVAWLFLFSKFIELMDTVIFILRKKDGQVTFLHVFHHSVLPWSWWWGVKIAPGGMGSFHAMINSSVHVIMYLYYGLSAFGPVAQPYLWWKKHMTAIQLIQFVLVSLHISQYYFMSSCNYQYPVIIHLIWMYGTIFFMLFSNFWYHSYTKGKRLPR---------------------------------------------------------------------------ALQQNGAPGIAKVKAN-----------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A0R4IT00-1", "uniprot_id": "A0A0R4IT00_DANRE", "id": "A0A0R4IT00-1", "name": "Elongation of very long chain fatty acids protein 1", "aln": "--------------------------------------------------------------------------------------------------------------------------------MLETVKDRVLEAYGSLLAAR-DPRLKDYPLMESPFSMTAILLAYLFFVLYAGPKFMANRKPFQLKEAMIIYNLSLVGLSAYIVYEFLMSGWAT----------------------------GYTWRCDPCDYSNSPQGLRMARVAWLFLFSKFIELMDTVFFVLRKKHSQITFLHIFHHSFMPWTWWWGVSIVPGGMGSFHAMVNSCVHVIMYFYYGLSAAGPRFQKFLWWKKYMTAIQLTQFVLVSLHVSQWYFMESCDFQVPVIIHLIWLYGTFFFVLFSNFWYQAYIKGKRLPKNTQETTKTN-----------------------------------GSTIVTNGSSGVSN---------------GHAIHENGLSNGKKHHENGNALNGKMKKA", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * * . : : * : * ** * :***::*. :::** * :* :.** *. :*:* :. * * . : : ::*. *: **.:*::**. *:: **: ** * : . .** .:: :*. :*: ** ** ::* ** :*****::* :*: ** .* : : .* : . :* :* *: * . ", "identical_positions": 61, "similar_positions": 61, "identity": "11.57%" }, { "cls_id": "homologset.agr.MGI:1858960", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9JLJ4-1", "uniprot_id": "ELOV2_MOUSE", "id": "Q9JLJ4-1", "name": "Very long chain fatty acid elongase 2", "aln": "--------------------------------MEQLKAFDNEVNAFLDNMFGPRDSRVRGWFLLDSYLPTFILTITYLLSIWLGNKYMKNRP-ALSLRGILTLYNLAITLLSAYMLVELILSSWEGGYNL-QCQNLDSAGEGDVRVAKVLWWYYFSKLVEFLDTIFFVLRKKTNQITFLHVYHHASMFNIWWCVLNWIPCGQSFFGPTLNSFIHILMYSYYGLSVFPSMHKYLWWKKYLTQAQLVQFVLTI-----------THTLSAVVKPCGFPFG---CLIFQSSYMMTLVILFLNFYIQTYRKKPVKKELQE----KEVKNGFPKAHLIVANGMTDKKAQ---------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D4A612-1", "uniprot_id": "ELOV2_RAT", "id": "D4A612-1", "name": "Very long chain fatty acid elongase 2", "aln": "-------------------------------------------------MFGPRDSRVRGWFLLDSYLPTFTLTIVYLLSIWLGNKYMKNRP-ALSLRGILTLYNLGITLLSAYMLVELVLSSWEGGYNL-QCQNLDSAGEGDIRVAKVLWWYYFSKLVEFLDTIFFVLRKKTSQITFLHVYHHASMFNIWWCVLNWIPCGQSFFGPTLNSFIHILMYSYYGLSVFPSMHRYLWWKKYLTQAQLVQFVLTI-----------THTLSAVVKPCGFPFG---CLIFQSSYMMTLVILFLNFYIQTYRKKPMKKEMPEGAAGKEVKNGFPKAHSIAANGVTDKKVQ---------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9NXB9-1", "uniprot_id": "ELOV2_HUMAN", "id": "Q9NXB9-1", "name": "Very long chain fatty acid elongase 2", "aln": "--------------------------------MEHLKAFDDEINAFLDNMFGPRDSRVRGWFMLDSYLPTFFLTVMYLLSIWLGNKYMKNRP-ALSLRGILTLYNLGITLLSAYMLAELILSTWEGGYNL-QCQDLTSAGEADIRVAKVLWWYYFSKSVEFLDTIFFVLRKKTSQITFLHVYHHASMFNIWWCVLNWIPCGQSFFGPTLNSFIHILMYSYYGLSVFPSMHKYLWWKKYLTQAQLVQFVLTI-----------THTMSAVVKPCGFPFG---CLIFQSSYMLTLVILFLNFYVQTYRKKPMKKDMQEPPAGKEVKNGFSKAYFTAANGVMNKKAQ---------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P25358-1", "uniprot_id": "ELO2_YEAST", "id": "P25358-1", "name": "Fatty acid elongase 2", "aln": "MNSLVTQYAAPLFERYPQLHDYLPTLERPFFNISLWEHFDDVVTRVTNGRFVPSEFQFIAGELPLSTLPPVLYAITAYYVIIFGGRFLLSKSKPFKLNGLFQLHNLVLTSLSLTLLLLMVEQLVPIIVQHGLYFAICNIGAWTQPLVTLYYMNYIVKFIEFIDTFFLVLKHKK--LTFLHTYHHGATALLCYTQLMGTTS-ISWVPISLNLGVHVVMYWYY---FLAARGIRVWWKEWVTRFQIIQFVLDIGFIYFAVYQKAVHLYFPILPHCGDCVGSTTATFAGCAIISSYLVLFISFYINVYKRKGTKTSRVVKRAHGGVAAKVNEYVNVDLKNVPTPSPSPKPQHRRKR", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * * : :. . : * **.. :: * :*.::: .:. .:.*.*:: *:** :* ** :* :: . : : . * :..: : *: * :**:**:*:**::*. :****.***.: : : * .. *:. :** :*::** ** .:.: :***:::*: *::**** * .* .:: ** .* . : .: : : ::**:.**::.*::* *.. * . : :.: . . ", "identical_positions": 65, "similar_positions": 99, "identity": "18.41%" }, { "cls_id": "homologset.agr.MGI:1858961", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I6APJ5-1", "uniprot_id": "A0A8I6APJ5_RAT", "id": "A0A8I6APJ5-1", "name": "", "aln": "------------------------------------------------------------------------------------MRRSE--VLADESIVCLQKALTHLREIWGLIGIPEEQRLQRTEVVKKHIKDLLDKMIAEEENLRERLLKSISICRKELSTLCSELQVK---------------------------------------PFEEDK--EITVLQLEKDLRTQVELMRKQKKERKQELKLLQEQDQELREILCMPP------------------------------CDVDSTSVPTLEELNLFRQRVATLRETKESRHEQFVNIKRQIILCMEELEHTPDTSF-------------ERDVVCEDESAFCLSLENIATLQKLLKQLEVKKSQNEAECEGLRAQIRELWDRLQIPEEEREPVAAIMTGSKTKIRNALKLEVDRLEELKMQNIKQVIETIRVELAQFWDQCFYSQEQRQAFAPYYSEDYT--------ENLLHLHDVEVIRLRNYYEAHKELFEGVQKWEESWKLFLEFERKASDPSRFTNRGGN--LLKEEKERAKLQKTLPKLEEELKARIEHWEQENSTAFVVNGQKFMEYVTEQ-------WELHRLEKERAKQERQ--LKNKRQTETEMLY----------------GSAPRTPSKRP---------GQTPNKCGKVRKMNTTTMSTATPNSSIRPVFGGSVYRSPMSRLPPSGSKSVVTSLCSGKKTPR--AARLRANKENLDLNGSILSGGYSGSTPLQRNCSIKSVASTYSEFSKDPSLSDSSTVGLQRELSKASRSDATSRILNSTNIQS------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q99K43-1", "uniprot_id": "PRC1_MOUSE", "id": "Q99K43-1", "name": "Protein regulator of cytokinesis 1", "aln": "------------------------------------------------------------------------------------MRRSE--VLADESITCLQKALTHLREIWELIGIPEEQRLQRTEVVKKHIKDLLDRMIAEEESLRERLLKSISICQKELSTLCSELQVK---------------------------------------PFQEEK--DTTILQLEKDLRTQVELMRKQKKERKQELKLLQEQEQELRDILCMPP------------------------------CDVDSTSVPTLEELKLFRQRVATLRETKESRREEFVNIKKQIILCMEELEHSPDTSF-------------ERDVVCEDESAFCLSLENIATLQKLLKQLEMKKSQNEAECEGLRTQIRELWDRLQIPEEEREPVEAIMTGSKTKIRNALKLEVDRLEELKMQNIKQVIEKIRVELAQFWDQCFYSQEQRQAFAPYYSEDYT--------ENLLHLHDAEIVRLRNYYDVHKELFQGVQKWEESWKLFLEFERKASDPGRFTNRGGN--LLKEEKERAKLQKTLPKLEEELKARIEQWEQEHSTAFVVNGQKFMEYVTEQ-------WELHRLEKERAKQERQ--LKNKKQTEAEMLY----------------GSTPRTPSKRP---------GQTPKKSG---KMNTTTMSSATPNSSIRPVFGGSVYRSPMSRLPPSGSKSVVTSLCSGKKTPR--AAQLRANKENLDLNGSILSGGYPGSTPLQHNCSIKSVASTYSEFS--------------RELSKASRSDATSRILNSTNIQS------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O43663-1", "uniprot_id": "PRC1_HUMAN", "id": "O43663-1", "name": "Protein regulator of cytokinesis 1", "aln": "------------------------------------------------------------------------------------MRRSE--VLAEESIVCLQKALNHLREIWELIGIPEDQRLQRTEVVKKHIKELLDMMIAEEESLKERLIKSISVCQKELNTLCSELHVE---------------------------------------PFQEEG--ETTILQLEKDLRTQVELMRKQKKERKQELKLLQEQDQELCEILCMPH------------------------------YDIDSASVPSLEELNQFRQHVTTLRETKASRREEFVSIKRQIILCMEALDHTPDTSF-------------ERDVVCEDEDAFCLSLENIATLQKLLRQLEMQKSQNEAVCEGLRTQIRELWDRLQIPEEEREAVATIMSGSKAKVRKALQLEVDRLEELKMQNMKKVIEAIRVELVQYWDQCFYSQEQRQAFAPFCAEDYT--------ESLLQLHDAEIVRLKNYYEVHKELFEGVQKWEETWRLFLEFERKASDPNRFTNRGGN--LLKEEKQRAKLQKMLPKLEEELKARIELWEQEHSKAFMVNGQKFMEYVAEQ-------WEMHRLEKERAKQERQ--LKNKKQTETEMLY----------------GSAPRTPSKRR---------GLAPNTPGKARKLNTTTMSNATANSSIRPIFGGTVYHSPVSRLPPSGSKPVAASTCSGKKTPR--TGRHGANKENLELNGSILSGGYPGSAPLQRNFSINSVASTYSEFAKDPSLSDSSTVGLQRELSKASKSDATSGILNSTNIQS------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1PAZ7-1", "uniprot_id": "A0A8M1PAZ7_DANRE", "id": "A0A8M1PAZ7-1", "name": "", "aln": "------------------------------------------------------------------------------------MRKSE--VIAAESVACLNKALCHLKDIWEEIGIPEDQRLERTNVVKNHVKGLLDMMIAEEESLRKRLMTSIEKCHKELSKLCLELQSP---------------------------------------PFQEEK--SGTMLQREKELRTHVEVMLKEKNQRMQALKALTEQDQDLCDLLCSQP------------------------------FSISPGCVPSMEQLENFHQHISCLTAEKERRHKEFVTLKKQIILCMDDLDQLPETSF-------------EKDVVCEDEESFCLSKENIDSLKVLLQQLENRKAENKRVCGSYREKILELWKRLQIPQEERDVISEHMTLSKKRNMEALQVEVKRLEELKLKNMQNVTETLRKEIAVYWEKCFYSADQRQAFMPYYDDDFS--------EELLSLHDAEIVQLKQYYEDHKELFEGVHKWEENWRLFIELEERAKDPSRFTNRGGN--LLKEEKQRADIVKGLPKLEKKLKAEIEQWELEQNREFQVNGQKFMQFVSDQ-------WELYRLEKEREKQERQ--LKKSKQTEEDMVY----------------GTVIRTPTKRR---------FLGSTTPCKARKLNP-TSSTGTSNSTIRSVIGGTVCHSPISRPPISASKGNGVKTPGHSKPPH--QGLLERNKENICHLTGGVAGMTKVPASPQRNFSINSVASTYSEFQ--------------RDLSKSSKSKHVPEILNSTIIQL------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VZ62-1", "uniprot_id": "Q9VZ62_DROME", "id": "Q9VZ62-1", "name": "", "aln": "------------------------------------------------------------------------------------MNSPSAIAVKAQILEMTGEHVDQLHAMWSQL-FEVKTCGEFLLRLKDHANSFFTDLLNESREKQQAILNDIAALRAEATDLTRLLHEP---------------------------------------LDIGERPESMPLVVWELKLDKSIEHLRDQLARRRAEICELLLQQEQLCEELGELP------------------------------LPLLADPLPLPEEMDAFRNRLGQLRDQRVLRLKEMDQLRQAIKHDMKLLECLPQTDT-------------EERLLNQVD--HCLTPETFELLRNMQKNFADQVKELRERIDDMREKIHVLWDRLQETDEYAMRRVREATTYTQRTYDVLREELQRCQALRRQNLKTFIEQLRIEIKEMWDLTLKSQQERKRFSNYYNDWYN--------EDLLELHELELDDLKTFYNKNKEIFDLYESRAELWSRMEALEAKASEPNRFNNRGGQ--LLKEEKERKAITSKLPKIEQQITELVQAYEAQENTPFLVHGENILERMAAD-------WERHRQAKQQSSARKKAPPSASKIMPPPATG----------------STAPRTPRTLRNM---STLSSSTMSLRKTPSQQHLRPLNITKSTGNLHKRLNPSGLQTGPKTPNAKRSLMNTLNSMKASPAKH--LLAPSQQHNQLKSTKSPLKRVRVLDNTLRRSGGMGRRSIGTRSSKK------------ARTKSNDQNAPPDSSDYTTDENPEQGVSYDEFQPTSRSSMLPRQRHQLAVPRTRRAEMNANLPVPRESLMIVQPRRQF", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VZ61-1", "uniprot_id": "Q9VZ61_DROME", "id": "Q9VZ61-1", "name": "", "aln": "------------------------------------------------------------------------------------MLSS---EHKARILALTAEHFDELHAMWSRM-FEPQACEDCLARLKDHVHTFYTDLRKETSDKEQGILNDIAVLRNEASGLRRLLHKA---------------------------------------VDIGERPDDVPMEIWYIKLEKYIEQLRKELVSRRAEIRELLHQQQQLCDELGEQP------------------------------LSLLADPLPLPEEMDPFREHLAQLRDQRVQRLRDMDELRQNIKRNIKLLELQLRTDS-------------EKRLLNADN--HKLTPYAYVRLQEMDKEFADQVQDLIDRIDEMRGKIECLWQRLRMTDEYAMRRVREATSYNQCTYDILREELERCQAMRQQNLIAFIEQLRIEINEWWDLSLKSTEERRRFTTYYCDTQT--------EDVLEQFEKELDNLKEFYNSNRKIFELYANRGELWTRMEALEAKANDPNRFNNRGGQ--LLKEEKERKTIMSRLPKIDQQITELVQVYMSETHTPFLVHGVDILERMSAD-------WERHRQSKKQPSAQKKDGSNTSGQMKPP--------------------MVPLTPNTQKSN---RGIHGSTSSLKKTPTKANAS--TTAMSTGNLHKRRHPQHHNTNSPQP-AAAAKRNLIASLECNNASR--KVCVNGQ----KLLKSPQRKVRVLEYSVRRGKGSGRPSTGSRNPQK------------IRPIPKIHVRPPSGEE---NESPDE-----------------------------------------EAVVAI------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P50275-1", "uniprot_id": "ASE1_YEAST", "id": "P50275-1", "name": "Anaphase spindle elongation protein", "aln": "METATSSPLPIKSRRNSENSGSTTVIPHMNPSLATPLTVSTMVNQSNSKEFMKLTPVRIRDFGSPLKNVSTNYHFLDSENGKGNTMDNMYRENFILISKDLEKLLENLNVIYQNIGYSNTEIITKEKIIFTTISNSIKQFFEQADEELKRLSAENGIEQDILNNILERINDPSGIKTIPDLYIRNAILLQESKTVPQSPKKPLSLLSKKAALDTAKKFVLGSFLPRLRDYLKSLITLKHLIQSVKENLPGLTEADNEAIAEFPELSTLTAYLLQIENGKGDIGLSMKFIIDNRKDILKGSAFKTINEESVKHMNEVIKIYEEEYERRFKSVLTKKVSISSICEQLGTPLATLIGEDFEQDLRSYGEEENSTSEIPNFHPVDRERMSKIDITLEKLQAIHKERADKKRLLMEQCQKLWTRLKISQEYIKTFMRNNSSLSTESLGRISKEVMRLEAMKKKLIKKLISDSWDKIQELWRTLQYSEESRSKFIIVFEELRNSATTLQEDELLLETCENELKRLEEKLTLYKPILKLISDFESLQEDQEFLERSSKDSSRLLSRNSHKILLTEEKMRKRITRHFPRVINDLRIKLEEADGLFDQPFLFKGKPLSEAIDIQQQEIEAKYPRCRVRMQRSKKGKCGANKENKVIKNTFKATESSIRVPIGLNLNDANITYKTPSKKTIQGLTKNDLSQENSLARHMQGTTKLSSPNRRATRLLAPTVISRNSKGNIERPTLNRNRSSDLSSSPRINHTHGEHAVKPRQLFPIPLNKVDTKGSHIPQLTKEKALELLKRSTGTTGKENVRSPERKSSLEDYAQKLSSPYKEPEHSIYKLSMSPEGKFQLNIQQKDIESGFDDTSMMEDENDKDFITWKNEQVSKLNGFSFTDI-----", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . .*. :: : : : : . : : . : . : :: . .. . . : : . : * ::: : . *.:. :.: : * ... : * . * * *. . : : .:: : : ** **: .:* : . : *: * : :: : : . . :: * * :.* * : . * :* : *: *. : ::. . . :* :.:..*: .*..: **.*** * : :*:: :.: :: * .:* : : : : : * :: . : . . . ** . . .. : . : : . .: : . ", "identical_positions": 38, "similar_positions": 132, "identity": "4.27%" }, { "cls_id": "homologset.agr.MGI:1858963", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q96EK6-1", "uniprot_id": "GNA1_HUMAN", "id": "Q96EK6-1", "name": "Glucosamine 6-phosphate N-acetyltransferase", "aln": "--MKPDETPMFDPSLLKEVDWSQNTATFSPAISPTHPGE-GLVLRPLCTADLNRGFFKVLGQLTETGVVSPEQFMKSFEHMKKSGDYYVTVVEDVTLGQIVATATLIIEHKFIHSCAKR------------GRVEDVVVSDECRGK----QLGKLLLST-LTLLSKKLNCYKITLECLPQNVGFYKKFGYTVS--EENYMCRRFLK------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9JK38-1", "uniprot_id": "GNA1_MOUSE", "id": "Q9JK38-1", "name": "Glucosamine 6-phosphate N-acetyltransferase", "aln": "--MKPDETPMFDPSLLKEVDWSQNTAIFSPAISPTHPGE-GLVLRPLCTADLNKGFFKVLGQLTETGVVSPEQFMKSFEHMKKSGDYYVTVVEDVTLGQIVATATLIIEHKFIHSCAKR------------GRVEDVVVSDECRGK----QLGKLLLST-LTLLSKKLNCYKITLECLPQNVGFYKKFDYTVS--EENYMCRRFLK------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8I6AKF3-1", "uniprot_id": "A0A8I6AKF3_RAT", "id": "A0A8I6AKF3-1", "name": "Glucosamine 6-phosphate N-acetyltransferase", "aln": "--MKPDETPMFDPSLLKEVDWSQNTAIFSPAISPMHPGE-GLVLRPLCTADLNKGFFKVLGQLTETGVVSPEQFMKSFEHMKKSGDYYVTVVEDVTLGQIVATATLIIEHKFIHSCAKSSFLLLQPVSSLTTRLKNAVVCQCSATRGCLWLLGVQMIRKGGDFLTKGIYFQLESFLALYFSTVCLPFLVVKSM--GSKQLCHLLSAAHF---------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9VAI0-1", "uniprot_id": "GNA1_DROME", "id": "Q9VAI0-1", "name": "Probable glucosamine 6-phosphate N-acetyltransferase", "aln": "MVQLTEETYLYDPNLLLKLDFHRSPANFKPFISAANPGEPWMKVRPLKDTDYDRGFLQLLSQLTHVGNVNRTQFLTRFSQMKASGDYFVTVIEDTRKNEIIGAASLVIERKFIHNCAVR------------GRLEDVVVNDTYRGK----QLGKLIVVT-VSLLAEELGCYKMSLDCKDKLIKFYESLGYVAIPGNSNSMTIRYDEGPTLKRNATSAGSSGTVGDSCQTVSLDFAS", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P43577-1", "uniprot_id": "GNA1_YEAST", "id": "P43577-1", "name": "Glucosamine 6-phosphate N-acetyltransferase", "aln": "-MSLPDGFYIRR---MEEGDLEQVTETLKVLTTVGTITP--------------ESFSKLIKYWNEATVWND-------NEDKKIMQYNPMVIVDKRTETVAATGNIIIERKIIHELGLC------------GHIEDIAVNSKYQGQ----GLGKLLIDQ-LVTIGFDYGCYKIILDCDEKNVKFYEKCGFSNAG---VEMQIRK--------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .: : : : * : . :. : ..* ::: ... . .. * :* *: * : .:..::**:*:**. . :::: .* . : ** :: : : . : ", "identical_positions": 14, "similar_positions": 47, "identity": "5.93%" }, { "cls_id": "homologset.agr.MGI:1858964", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P61163-1", "uniprot_id": "ACTZ_HUMAN", "id": "P61163-1", "name": "Alpha-centractin", "aln": "---MESYDVIANQPVVIDNGSGVIKAGFAGDQIPKYCFPNYVGRPKHVRVMAGALEGDIFIGPKAEEHRGLLSIRYPMEHGIVKDWNDMERIWQYVYSKDQLQTFSEEHPVLLTEAPLNPRKNRERAAEVFFETFNVPALFISMQAVLSLYATGRTTGVVLDSGDGVTHAVPIYEGFAMPHSIMRIDIAGRDVSRFLRLYLRK-EGYDFHSSSEFEIVKAIKERACYLSINPQKDE-----TLETEKAQYYLPDGSTIEIGPSRFRAPELLFRPDLIGEESEGIHEVLVFAIQKSDMDLRRTLFSNIVLSGGSTLFKGFGDRLLSEVKKLAPKDVKIRISAPQERLYSTWIGGSILASLDTFKKMWVSKKEYEEDGARSIHRKTF", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P85515-1", "uniprot_id": "ACTZ_RAT", "id": "P85515-1", "name": "Alpha-centractin", "aln": "---MESYDVIANQPVVIDNGSGVIKAGFAGDQIPKYCFPNYVGRPKHVRVMAGALEGDIFIGPKAEEHRGLLSIRYPMEHGIVKDWNDMERIWQYVYSKDQLQTFSEEHPVLLTEAPLNPRKNRERAAEVFFETFNVPALFISMQAVLSLYATGRTTGVVLDSGDGVTHAVPIYEGFAMPHSIMRIDIAGRDVSRFLRLYLRK-EGYDFHSSSEFEIVKAIKERACYLSINPQKDE-----TLETEKAQYYLPDGSTIEIGPSRFRAPELLFRPDLIGEESEGIHEVLVFAIQKSDMDLRRTLFSNIVLSGGSTLFKGFGDRLLSEVKKLAPKDVKIRISAPQERLYSTWIGGSILASLDTFKKMWVSKKEYEEDGARSIHRKTF", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P61164-1", "uniprot_id": "ACTZ_MOUSE", "id": "P61164-1", "name": "Alpha-centractin", "aln": "---MESYDVIANQPVVIDNGSGVIKAGFAGDQIPKYCFPNYVGRPKHVRVMAGALEGDIFIGPKAEEHRGLLSIRYPMEHGIVKDWNDMERIWQYVYSKDQLQTFSEEHPVLLTEAPLNPRKNRERAAEVFFETFNVPALFISMQAVLSLYATGRTTGVVLDSGDGVTHAVPIYEGFAMPHSIMRIDIAGRDVSRFLRLYLRK-EGYDFHSSSEFEIVKAIKERACYLSINPQKDE-----TLETEKAQYYLPDGSTIEIGPSRFRAPELLFRPDLIGEESEGIHEVLVFAIQKSDMDLRRTLFSNIVLSGGSTLFKGFGDRLLSEVKKLAPKDVKIRISAPQERLYSTWIGGSILASLDTFKKMWVSKKEYEEDGARSIHRKTF", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P45889-1", "uniprot_id": "ACTZ_DROME", "id": "P45889-1", "name": "Actin-related protein 1", "aln": "---MEPYDVVVNQPVVIDNGSGVIKAGFAGEHIPKCRFPNYIGRPKHVRVMAGALEGDIFVGPKAEEHRGLLSIRYPMEHGIVTDWNDMERIWSYIYSKEQLATFTEDHPVLLTEAPLNPRRNREKAAEFFFEGINAPALFVSMQAVLSLYATGRVTGVVLDSGDGVTHAVPIYEGFAMPHSIMRVDIAGRDVTRYLKTLIRR-EGFNFRSTAEFEIVRSIKEKVCYLATNPQKEE-----TVETEKFAYKLPDGKIFEIGPARFRAPEVLFRPDLLGEECEGIHDVLMYSIEKSDMDLRKMLYQNIVLSGGSTLFKGFGDRLLSELKKHSAKDLKIRIAAPQERLYSTWMGGSILASLDTFKKMWISKREYEEEGQKAVHRKTF", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P38696-1", "uniprot_id": "ARP1_YEAST", "id": "P38696-1", "name": "Centractin", "aln": "MDQLSDSYALYNQPVVIDNGSGIIKAGFSGEERPKALEYCLVGNTKYDKVMLEGLQGDTFIGNNAQKLRGLLKLRYPIKHGVVEDWDSMELIWSYVLNEVLQLQNIGEHPLLITEAPMNPLKNREQMAQVLFETFDVSALYVSNPAVLSLYASGRTTGCVVDCGEGYCSTVPIYDGFALPASMMRMDIGGADITEQLQFQLRKSAGVSLFSSSEREIVRTMKEKVCYLAKNIKKEEEKYLQGTQDLISTFKLPDGRCIEVGNDRYRAPEILFSPQIIGLGYDGLSDMCMQSIWKVDLDLRKPLLSSIILSGGTTTLKGFGDRMLWDLEALTKGTSKIKIIAPSERKYTTWIGGSILTGLSTFQRLWTKKSDWLEDSTR-VYSNLM", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :. .: ***********:*****:*:. ** :*..*: :** .*:** *:* :*:: ****.:***::**:* **:.** **.*: .: :**:*:****:** :***: *:.:** ::..**::* *******:**.** *:*.*:* :****:***:* *:**:**.* *::. *: :*: * .: *::* ***:::**:.***: * :*:* : : **** :*:* *:****:** *:::* :*: :: : :* * *:***: * ..*:****:* :******:* ::: : **:* **.** *:**:*****:.*.**:::* .* :: *:. : :: : :", "identical_positions": 167, "similar_positions": 121, "identity": "43.38%" }, { "cls_id": "homologset.agr.MGI:1858965", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I5ZNS2-1", "uniprot_id": "A0A8I5ZNS2_RAT", "id": "A0A8I5ZNS2-1", "name": "", "aln": "MHQDLRFKMDNIEEPQKKVFKARKTMRASDRQQLDAVHRVKEELLRTDGKLLNGNHENGDLDPTSPLENTDCIQDKEEVNGVDGICFESEESKTEWKETPCIPTVGVKNKQED-LNSEALSPSITSDLASKVTTEPASGTPASDNPGCDTLASDNPGCDTLASDNPASDNPASDNPASDNPGSGDLAAGELTTRVPTAGESACEELPSSHPSSSDPSSSDPTFSDPCCSDPVSGDTASEEPTSDALASGDSASGDSASGEPVSHEPASSE-----PASEERVTGAVASCDLASGESALDDCVTSGDSPSDDLPSSEESLRTSVCSRLASGELIPGELTVESATD-SFKPSSVPVCEPGPDTDKTEQNSKNNDDCPDRNDDDEDLAQIQSKDAFDEGNKVNSNVAEKEGTLETHSAIIHSDHLPPENTKKVEEDAVAEPALEEEAISSSMEVDQSEKDRHKSPVELVDAASEDPTEEGKKNTVSDNTDSMETDEIIPILEKLAPTEDELSCFSKTSLLPVETS-QDLEDKMEGSFGSPSKQESSENLPKEAFLVLSDEEDISCGKDESEVLAQNKTSSP-EGERSEKDSKAEEEKRVPDE--ERPPGRNEFSRRKRSKSEDMDSVQSKRRRYMEEEYEAEFQVKITAKGDINQKLQKVIQWLLEEKLCALQCAVFDKTLAELKTRVEKIECNKRHKAVLT---ELQAKIARLTKRFGAAKDDLKKRQESPPNPPISPGKPANDVNSNNNVTYRNAGTVRQLLESKRNISEGPPPSFQTPVNTVSSASHGPSSAAVSSQPKVQPSATSGSLPAAPLLPVPSTATVVATTQVPSGNPQPTISLQPLPVILHVPVAVTSQPQLLQSHPGTLVTNQPSGNVEFISVQSQPTVSGLTKTPVSLPPLPNPTKPN-IPSVPSPS-IQRNSSATAAPLGTTLAVQAVPTAHSIVQATRTSLPPVGPSGLYSSSSSRGSIQMKIPIPAFSTSSSAEQSSSATPR--AENQTNKTVDSAVNKKAADSTSQSGKASSNDSSGVIDLTMDDEDSGTTQDPKKLNPPSASTVSTSQPMSRPLQPILPAPPLQPSGVPTSGPSQATIHVLPTAPTTVNVTHRPVTQVTTRLPVPRAPANHQVVYTTLPAPTTQAPLRGTVMQAPAVRQVNPQNSVTVRVPQTTTYVVNNGLTLGSAGPQLTVHHRPPQVHNEPPRPLHPAPLPEAPQP-QRLPPEAANTSLPQKPHLKLARVQSQNGIVLSWSVLEVDRSCATVDSYHLYAYHEEPSATAP-----SQWKKIGEVKALPLPMACTLTQFVSGSKYYFAVRAKDIYGRFGPFCDPQSTDVISSSQSS--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q7TT18-1", "uniprot_id": "MCAF1_MOUSE", "id": "Q7TT18-1", "name": "Activating transcription factor 7-interacting protein 1", "aln": "--------MDSVEEPQKKVFKARKTMRASDRQQLDAVHRVKGELLRADGKLLNGSHENGDLDPTSPLENTDCIQDREEVNGIDGICFQSEESTTEWKETPCMPNVAVKNKQED-LNSEALSPSITCDLSSRVTTEPGSGSPASDNPGCGTPVSDN----------PASDNPASDNPASDNPDSGDLAAGELATTVQATGDSACEEPPSSDPSSSDPTSSEPSSSEPTCSEPISGDPVSEEAASHDLVSGDSTCSEPVSGEPVSHEAASSEPATSEPASDEPVARVVAACELAPGESALDDCAPSGDSQSDEPPSSEDSLPRSVCSGLASGELTPGELSVEPATD-TVKPSSSAVCEAGPDPDKTEPSSNNSDDCPGKSEDDEHLDQIQSKDSCDEGNKVNSNVVEKEEPLETHSAIICSD-LPPENTTKIAEDPIAEPALEEEAISSSMEVDQSEKDEHKSPAEPVAAVSEDPAEEDKEDTVVDNTDSMETDEIIPILEKLAPTEDELSCFSKASLLPVETS-QDLEDKMEGSFGSPSKQESSENLPKEAFLVLSDEEDLSCGKDESEAVAQSKMSTP-EGEKSEKDGKAEEEERVPAE--EQPPVRNEFSRRKRSKSEDMDSVESKRRRYMDEEYEAEFQVKITAKGDINQKLQKVIQWLLQEKLCALQCAVFDKTLAELKTRVEKIECNKRHKAVLT---ELQAKIARLTKRFGAAKDDLKKRQESPPNPPISPGKPANDTNSNNNMTYRNAGTVRQLLESKRNVSEGPPPSFQTPVNTVSSASHATSTAVVSSQPKLQTSATSGSLPAAPLLPAPSTATVVATTQVPSGTPQPTISLQPLPVILHVPVAVTSQPQLLQSHPGTLVTNQPSGNVEFISVQSQPTVSGLTKNPVSLPPLPNPTKPN-IPSVPSPSSIQRNSSTTAAPLGTTLAVQAVPTAHSIVQATRTSLPTVGPSGLYSSSSSRGPIQMKIPISTFSPPSSAEQNSSATPRIVTENQTNKTVDSSINKKAADSTSQSGKASSSDSSGVIDLTMDDEESGTTQDPKKISPPSSSTVSTSQPMSRPLQPILPAPPLQPSGVPTSGPSQATIHVLPTAPTTVNVTHRPVTQVTTRLPVPRAPANHQVVYTTLPAPTTQAPLRGTVMQAPAVRQVNPQNSVTVRVPQTTTYVVNNGLTLGSAGPQLTVHHRPPQVHNEPPRPLHPAPLPEAPQP-QRLPPEAASTSLPQKPHLKLARVQSQNGIVLSWSVLEVDRSCATVDSYHLYAYHEEPSATVP-----SQWKKIGEVKALPLPMACTLTQFVSGSKYYFAVRAKDIYGRFGPFCDPQSTDVISSSQNS--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6VMQ6-1", "uniprot_id": "MCAF1_HUMAN", "id": "Q6VMQ6-1", "name": "Activating transcription factor 7-interacting protein 1", "aln": "--------MDSLEEPQKKVFKARKTMRVSDRQQLEAVYKVKEELLKTDVKLLNGNHENGDLDPTSPLENMDYIKDKEEVNGIEEICFDPEGSKAEWKETPCILSVNVKNKQDDDLNCEPLSP-------HNITPEPVSKLPA--------------------------------EPVSGDPAPGDLDAGDPASGVLASGDSTSGDPTSSEPSSSDAASGDATSGDAPSGDVSPGDATSGDATADDLSSGDPTSSDPIPGEPVPVEPISGD-----CAADDIASSEITSVDLASG------APASTDPASDDLASGDLSSSELASDDLATGELASDELTSESTFDRTFEPKSVPVCEPVPEIDNIEPSSNKDDDFLEKNGADEKLEQIQSKDSLDEKNKADNNIDANEETLETDDTTICSD-RPPENEKKVEEDIITELALGEDAISSSMEIDQGEKNEDETSADLVETINENVIEDNKSENILENTDSMETDEIIPILEKLAPSEDELTCFSKTSLLPIDETNPDLEEKMESSFGSPSKQESSESLPKEAFLVLSDEEDISGEKDESEVISQNETCSPAEVESNEKDNKPEEEEQVIHEDDERPSEKNEFSRRKRSKSEDMDNVQSKRRRYMEEEYEAEFQVKITAKGDINQKLQKVIQWLLEEKLCALQCAVFDKTLAELKTRVEKIECNKRHKTVLT---ELQAKIARLTKRFEAAKEDLKKRHEHPPNPPVSPGKTVNDVNSNNNMSYRNAGTVRQMLESKRNVSESAPPSFQTPVNTVSSTNLVTPPAVVSSQPKLQTPVTSGSLTATSVLPAPNTATVVATTQVPSGNPQPTISLQPLPVILHVPVAVSSQPQLLQSHPGTLVTNQPSGNVEFISVQSPPTVSGLTKNPVSLPSLPNPTKPNNVPSVPSPS-IQRNPTASAAPLGTTLAVQAVPTAHSIVQATRTSLPTVGPSGLYSPSTNRGPIQMKIPISAFSTSSAAEQNSNTTPR--IENQTNKTIDASVSKKAADSTSQCGKATGSDSSGVIDLTMDDEESGASQDPKKLNHTPVSTMSSSQPVSRPLQPIQPAPPLQPSGVPTSGPSQTTIHLLPTAPTTVNVTHRPVTQVTTRLPVPRAPANHQVVYTTLPAPPAQAPLRGTVMQAPAVRQVNPQNSVTVRVPQTTTYVVNNGLTLGSTGPQLTVHHRPPQVHTEPPRPVHPAPLPEAPQP-QRLPPEAASTSLPQKPHLKLARVQSQNGIVLSWSVLEVDRSCATVDSYHLYAYHEEPSATVP-----SQWKKIGEVKALPLPMACTLTQFVSGSKYYFAVRAKDIYGRFGPFCDPQSTDVISSTQSS--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0JME2-1", "uniprot_id": "MCAF1_DANRE", "id": "A0JME2-1", "name": "Activating transcription factor 7-interacting protein 1", "aln": "------MEVAVPEEPQKKIFRARKTMKMSDRQQLEVLHNT----------LATTNSSLSSSPPQTPLMNGTHTETEKDLNNKEGDLMAPATDSARCSPSPSFP-------------------------------------------------------------------------VSRSPSPPNTQTTSPAMDLEDPLVATEEKKETSNKSSSSSPSASPAG--------------------------------------------------------------------------------------------------------------------------------------------LNCDPEVKEGFLCLSEEDETQADKDEKDSSEEKMNVDAETEDQKEEKDEKDTDTPEN-----------------------------------AEDNSAPVGLKRTLSE--------------------------------------------------------------------------------------------------------------EKDEDDKEIEEER------------------------------DGKRARLEGEELEAQLELKITANGGNRDKIEKMVQQLVEERLRVLQLTVFDRSLKELKDRVEKIDNVTKQQNALQHINTLQAKISRLAKKFGAANQASENAKRTQDAQAAAAAAQANNATNATTPQRTVKTTVDSKLSSSPTVSNSTAVPAQPKPLSTPATPTSSALATTAPILQIISTTTSSTPSSTSLPGQSQTGTLLLKTGPNPTVMTNAPATSGGQPVAMQQLLIQLPLAMANGQSGALVN--AAGGVGLIPVSSLSTVSNINKAKTTTPATTFMLQKT----------AGNVSSATSSAPAVSLARAVYPGGTGTVSSPNTGISVTTAR---TPTQCAAVVGVSTAAASPGTTGPAATGSAAAAAG-----SPSASALASKTDNQASTPKTASQPGRPKGSVIDLTEDDDDVQVTGVQKATVSPVTTQRSS-------------GPPPLVSSTPNTG-------------------------------------------------------------------------------------------TGVRSAQRSTVDSPSQSRPSSSSSTSLPPLPLAPSPPARLPPEANHTSPPQQPQLKLARVQSQNGIVLSWCVAETDRNCAAVDTYHLYAYHQDHQSSVSGASAQMLWKKIGEVKALPLPMACTLTQFVSGSTYYFAVRAKDVYGRFGPFCEPQCTDVITPASSAST", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : ******:*:*****: ******:.::.. * . . . .. * :** * : .:::*. : : . ..:. . :*.: .* .* . : : . : : . :: . :*. ***...*...: : ..: .:. . ** : :.**: :* :.: : :: : ..: .: : ..:.. : .* * .*.* : ***. :.** * ** **::::****:*. .:*::*::* *::*:* .** :***::* *** *****: .::: .* *****:**:*:* **:: :: :. . :.. .*:... .. ** . *.*. .:*:... . *. :..:: .. *..:. :: ...**.: .::.: ..*.*:: .* . : : . : : : : :.:.*:**. .:*.* :*.*.* .***.:.* .: *. . : . . .:::::. ..:** . * . . *.:..*.:. . . :.: . : :. . .: .....* .* ::. : .: : ... **.: .. .. ...***** **:: .: * . : *: .** *..*.:* * ..* :. . *.* : ... . .*** **.* ****** ** **:*:****************.* *.**.**:**:*******:: .::.. *************************.*********:********:**.****:.:..: ", "identical_positions": 237, "similar_positions": 315, "identity": "17.65%" }, { "cls_id": "homologset.agr.MGI:1859016", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q6MG60-1", "uniprot_id": "DDAH2_RAT", "id": "Q6MG60-1", "name": "Putative hydrolase DDAH2", "aln": "MGTPGEGLGRCSHALIRGVPESLASGEGAGAGLPALDLAKAQREHGVLGGKLRQRLGLQLLELPPEESLPLGPLLGDTAVIQGDTALITRPWSPARRPEVDGVRKALQ-DLGLRIVEMGDENATLDGTDVLFTGREFFVGLSKWTNHRGAEIVADTFRDFAVSTVPVSGASHLRGLCGMGGPRTVVAGSSEAAQKAVRAMAALTDHPYASLTLPDDAASDCLFLRPGLPGTTPFLLHRGGGDLPNSQEALQKLSDVTLVPVSCSELEKVGAGLSSLCLVLSTRPHC---", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q99LD8-1", "uniprot_id": "DDAH2_MOUSE", "id": "Q99LD8-1", "name": "Putative hydrolase DDAH2", "aln": "MGTPGEGLGRCSHALIRGVPESLASGEGAGAGLPALDLAKAQREHGVLGGKLRQRLGLQLLELPPEESLPLGPLLGDTAVIQGDTALITRPWSPARRPEVDGVRKALQ-DLGLRIVEMGDENATLDGTDVLFTGREFFVGLSKWTNHRGAEIVADTFRDFAVSTVPVSGSSHLRGLCGMGGPRTVVAGSSEAAQKAVRAMAALTDHPYASLTLPDDAASDCLFLRPGLPGATPFLLHRGGGDLPNSQEALQKLSDVTLVPVSCSELEKAGAGLSSLCLVLSTRPHC---", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O95865-1", "uniprot_id": "DDAH2_HUMAN", "id": "O95865-1", "name": "Putative hydrolase DDAH2", "aln": "MGTPGEGLGRCSHALIRGVPESLASGEGAGAGLPALDLAKAQREHGVLGGKLRQRLGLQLLELPPEESLPLGPLLGDTAVIQGDTALITRPWSPARRPEVDGVRKALQ-DLGLRIVEIGDENATLDGTDVLFTGREFFVGLSKWTNHRGAEIVADTFRDFAVSTVPVSGPSHLRGLCGMGGPRTVVAGSSDAAQKAVRAMAVLTDHPYASLTLPDDAAADCLFLRPGLPGVPPFLLHRGGGDLPNSQEALQKLSDVTLVPVSCSELEKAGAGLSSLCLVLSTRPHS---", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VYF0-1", "uniprot_id": "Q9VYF0_DROME", "id": "Q9VYF0-1", "name": "", "aln": "------MSPKYTHAIVARISDALLEN-----GKFDVQLAKQQHEQYCT---LLRTIGLDVIELPPDDQLPEGVFVENSAVICNGVALIGRSEHPKRQLEAESMAIILKKELDIPVIEIEDPNAQLDGGDVLFTGREFFVGISSFTNEEGARAVAMAYPEYPVTPIRVNGTKRLKYYVTMAGPEVLCVSSSPTCQEIVKRMEREAICTYQKLTLPEESAANMLYING-------TIVHRSPTEIPEAYKTLKEKIDIPTRNINISEFSQYSSGLTSSCLLLRRWKSIRSL", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : :**:: :.::* .. * ::*** *:*: * : :**:::****::.** * :: ::*** ...*** *. * *: *.:.: *: :*.: ::*: * ** *** ************:*.:**..**. ** :: ::.*:.: *.*..:*: *.**..: ..** :.*: *: * : .* .****:::*:: *::. ::**. ::*:: ::*:: *:. :. **:.: .:**:* **:* ", "identical_positions": 89, "similar_positions": 104, "identity": "30.8%" }, { "cls_id": "homologset.agr.MGI:1859017", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q99L85-1", "uniprot_id": "ELP5_MOUSE", "id": "Q99L85-1", "name": "Elongator complex protein 5", "aln": "------------------MLDSLLA---IGGLVLLRDSVEWE--GRSLLKALIKKSALRGEQVHVLGCEVSEEEFREGFDSDVNSRLVYHDLFRDPLNWS-KPGEAVPEGPLKALRSMCKRTDHG-SVTIALDSLSWLLCHIPCVTLCQALHALSQQNGDPGDNSLVEQVRVLGLLHEELHGPGSMGALNTLAHTEVTLSGKVD--QTSASILCRRPQQRATYQTWWFSVLP-DFSLTLHEG--LPLRSELHPDHHT-----TQVDPTAHLTFNLHLSKKEREARDSLTLPFQFSSEKQKALLHPVPSRTTGHIFYEPDAFDDVDPEDPDDDLDI", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6IUP3-1", "uniprot_id": "ELP5_RAT", "id": "Q6IUP3-1", "name": "Elongator complex protein 5", "aln": "MPRLLSGDDIRRRPEASEMLDSLLA---TGGLVLLRDSVEWE--GRGLLKALIKKSALRGEQVHVLGCEVSEEEFREGLGSDVNSRLVYHDLFRDPLNWS-QPGEAAPEGPLKALRSMCRRTDRG-SVTIALDSLSWLLCHIPCVTLCQALHALSQRNVDPGDNPLIEQVRVLGLLHEELHGPGPVGAVSSLAHTEVTLSGKMD--QTSASILCRRPQQRATYQTWWFSILP-DFSLDLHEG--LPLHSELHRDPHT-----TQVDPASHLTFNLHLSKKEREAKDSLTLPFQFSSEKQQALLHPVPGQTTGRIFYEPDAFDDVDQEDPDDDLDI", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8TE02-5", "uniprot_id": "ELP5_HUMAN", "id": "Q8TE02-5", "name": "Elongator complex protein 5", "aln": "------------------MLDSLLA---LGGLVLLRDSVEWE--GRSLLKALVKKSALCGEQVHILGCEVSEEEFREGFDSDINNRLVYHDFFRDPLNWS-KTEEAFPGGPLGALRAMCKRTDPV-PVTIALDSLSWLLLRLPCTTLCQVLHAVSHQDSCPGDSSSVGKVSVLGLLHEELHGPGPVGALSSLAQTEVTLGGTMG--QASAHILCRRPRQRPTDQTQWFSILP-DFSLDLQEG--PSVESQPYSDPHI-----PPVDPTTHLTFNLHLSKKEREARDSLILPFQFSSEKQQALLRPRPGQATSHIFYEPDAYDDLDQEDPDDDLDI", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A1A5V9-1", "uniprot_id": "ELP5_DANRE", "id": "A1A5V9-1", "name": "Elongator complex protein 5", "aln": "-----------------MLLEVLQAAE-AGGFILIQDSVQCC--GRGILRCCINAALKRDEDVHVLGFESPETEVCAGLDSSFAQKLHFHKGFPDPLGWRGKSSFTVQQFTSQHITQLIRDSQPAKASVLVVDSLSLVLRHHDPVIVCQSLQELRKGG--------VVKT-IIGLLHSDLHLQGIVGIVCHLASTVISVAPTNNERHAVATTTRRTKSGKVMQEEEYFSVSE-DATLSVQSK--PRQHDRVEKEQDS-----AEVDPASNLTFNLRLSEEERRAKEKVALPFVFSQEKKSALLRPTPG--SGRIMYEPDANDDFDEEDPDDDLDV", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q24050-1", "uniprot_id": "ELP5_DROME", "id": "Q24050-1", "name": "Elongator complex protein 5", "aln": "------------------MLSNLVVT--KQKVVLVIDELNRERIAPKFIGSLLHEQGQGADTIKALPTGVSLKHVAT-------------------------FEALIDKYANNNTGSTTDSNSTG--FNVILPTLADLLCYQTPAFIFGFLNRLRRSD--------NVRRVFLWASPQHLQDPHADYILAGCEYLAELVLRLES--DKLLSLISRKPGGGVSNRRYSCEVSKTQFKVTPLDGGLPAGASPKQPSPEA-----EQTTEPASSTFKIELDEDEVLARNALTLPYERTSEPS-----------EGNIIYTPDADDDFDEEDPDEDLCI", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P38874-1", "uniprot_id": "ELP5_YEAST", "id": "P38874-1", "name": "Elongator complex protein 5", "aln": "--------MASSSHNPVILLKRILSLTESSPFILCLDSIAQT--SYKLIQEFVHQSKSKGNEYPIVYISFETVNKPS-----YCTQFIDATQMDFVHLVKQIISYLPAATATQAKKHMVIIDSLNYISTEYITRFLSEIASPHCTMVATYHKDIKDENRTVIPDWNNNYPDKLTLLQFMATTIVDIDVVLTGTLDTEEVSELLNEFRIPRGLNNDIFQLRLVNKRKSGRSLEYDFIVNSNTHEYELLSTTKQEEESSSNGLETPEMLQGLTTFNLGTSNKQKLAKDQVALPFLEAQSFGQ----------GGAIVYEYEKDDDYDEEDPYEDPF-", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :*. : .:* *.: . :: :: : : . . . : : : . : : : . : : : . . : : . **:: .:.: *:: : **: :.. . *.* : ** * *** :* ", "identical_positions": 17, "similar_positions": 50, "identity": "5.07%" }, { "cls_id": "homologset.agr.MGI:1859026", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O95628-1", "uniprot_id": "CNOT4_HUMAN", "id": "O95628-1", "name": "CCR4-NOT transcription complex subunit 4", "aln": "-------------------MSRSPDAKEDPVECPLCMEPLEIDDINFFPCTCGYQICRFCWHRIRTDE--NGLCPACRKPYPEDPAVYKPLSQE-------ELQRIKNEKKQKQNERKQKISENRKHLASVRVVQKNLVFVVGLSQRLADPEVLKRPE---YFGKFGKIHKVVINNSTSYAGSQ--------GPSASAYVTYIRSEDALRAIQCVNNVVVDGRTLKASLGTTKYCSYFLKNMQCPKPDCMYLHELGDEAASFTKEEMQAGKHQEYEQKLLQELY-----------------KLNPNFLQLST---GSVDKNKNKVTP------------LQRY--------------------------------------------------------------DTPIDKPSDSLSIGNGDNSQQISN--------------------SDTPSPPPGLSKSNPVIPISSSNHSAR------------------------------SPFEGAVTES---QSLFSDN--FRHPNPIPSG------------------------LPPFPSSPQTSSDWPTAP--------------------------------------EPQSLFTSETIP------------------------------VSSSTDWQAAFG---FGSSK------------------------QPEDDLGFDPFDVTR-------------------KALADLIEKELSVQDQP-------------------SLSPTSLQNSSSHTTTAKGPGSGFLHPAAATNANSLNSTFSV------LPQRFPQFQQHRAVYN---SFSFPG-QAARYPWMAFP-RNSIMHLN-HTANPTSNSNFLDLNLPPQHN-TGLGGIPVAGEE----------------------EVKVSTMPLSTSS----------------------------------------------------HSLQQGQQPTSLHTTVA--------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8BT14-1", "uniprot_id": "CNOT4_MOUSE", "id": "Q8BT14-1", "name": "CCR4-NOT transcription complex subunit 4", "aln": "-------------------MSRSPDAKEDPVECPLCMEPLEIDDINFFPCTCGYQICRFCWHRIRTDE--NGLCPACRKPYPEDPAVYKPLSQE-------ELQRIKNEKKQKQNERKQKISENRKHLASVRVVQKNLVFVVGLSQRLADPEVLKRPE---YFGKFGKIHKVVINNSTSYAGSQ--------GPSASAYVTYIRSEDALRAIQCVNNVVVDGRTLKASLGTTKYCSYFLKNMQCPKPDCMYLHELGDEAASFTKEEMQAGKHQEYEQKLLQELY-----------------KLNPNFLQLST---GSVDKNKNKVTP------------LQRY--------------------------------------------------------------DTPIDKPSDSLSIGNGDNSQQISN--------------------SDTPSPPPGLSKSNPVIPISSSNHSAR------------------------------SPFEGAVTES---QSLFSDN--FRHPNPIPSG------------------------LPPFPSSPQTPSDWPTAP--------------------------------------EPQSLFTSETIP------------------------------VSSSTDWQAAFG---FGSSK------------------------QPEDDLGFDPFDVTR-------------------KALADLIEKELSVQDQP-------------------SLSPTSLQNASSHTTTAKGPGSGFLHSAAPTNANSLNSTFSV------LPQRFPQFQQHRAVYN---SFGFPG-QAARYPWMAFP-RNSIMHLN-HTANPTSNSNFLDLNLPPQHN-TGLGGIPIAGEE----------------------EVKVSTMPLSASS----------------------------------------------------HSLQQGQQPTSLHTTVA--------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0ABZ3NNF0-1", "uniprot_id": "A0ABZ3NNF0_RAT", "id": "A0ABZ3NNF0-1", "name": "CCR4-NOT transcription complex subunit 4", "aln": "-------------------MSRSPDAKEDPVECPLCMEPLEIDDINFFPCTCGYQICRFCWHRIRTDE--NGLCPACRKPYPEDPAVYKPLSQE-------ELQRIKNEKKQKQNERKQKISENRKHLASVRVVQKNLVFVVGLSQRLADPEVLKRPE---YFGKFGKIHKVVINNSTSYAGSQ--------GPSASAYVTYIRSEDALRAIQCVNNVVVDGRTLKASLGTTKYCSYFLKNMQCPKPDCMYLHELGDEAASFTKEEMQAGKHQEYEQKLLQELY-----------------KLNPNFLQLST---GSVDKNKNKVTP------------LQRY--------------------------------------------------------------DVPIDKPSDSLSIGNGDNSQQISN--------------------SDTPSPPPGLSKSNPVIPISSSNHSAR------------------------------SPFEGAVTES---QSLFSDN--FRHPNPIPSG------------------------LPPFPSSPQTPSDWPTAP--------------------------------------EPQSLFTSETIP------------------------------VSSSTDWQAAFG---FGSSK------------------------QPEDDLGFDPFDVTR-------------------KALADLIEKELSVQDQP-------------------SLSSTSLQNSSSHTTSAKGPGSGFLHPAAPANANSLNSTFSV------LPQRFPQFQQHRAVYN---SFGFPG-QAARYPWMAFP-RNSIMHLN-HTANPTSNSNFLDLNLPPQHN-TGLGGIPIADNNSSVESLNMKEWQDGLRALLPNININFGGLPNSSSPSNANHSAPTSNT-------ATTDSVSWDSPGSWTDPAIITGIPASSGNTL--DSIQDDNPPHWLKSLQALTEVD----GPSAASPQPHHSAP----FSTQIPLHRASWNPYPPP--SNPSSFHSPPPGFQTAFRPPSKTPTDLLQSSTLDRH---------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0A286YAE5-1", "uniprot_id": "A0A286YAE5_DANRE", "id": "A0A286YAE5-1", "name": "CCR4-NOT transcription complex subunit 4", "aln": "-------------------MSRSPELKEDPMECPLCMEPLEIDDVNFFPCTCGYQICRFCWHRIRTDE--NGLCPACRKPYPEDPAVYKPLSQE-------EIQRIKNEKKQKLNEKKQKVTENRKHLASVRVVQRNLVFVVGLSQRLADAEVLKRPE---YFGKFGKIHKVVINNSTSYAGSQ--------GPSASAYVTYIRSEDALRAIQCVNNVIVDGRTLKASLGTTKYCSYFLKSMQCPKPDCMYLHELGDEAASFTKEEMQAGKHQEYEQKLLQDLY-----------------KANPTFLLTSTC--GEKSKSKSNSTQRPNSTNKEGWPSLQNYGKMVNGLTTEHRKSPPLLDCLTDSDHMTPDEPDLEQGTEQNTGL---------PPFPSALEPTSPIDKPSEPISIGNGENISQTSS--------------------SDSPSPPPGLTKPSLVVPISVAELTAR------------------------------SPFEGAAAES---QSLFSDNSNFRHPNPIPSG------------------------LPPFSNSPQGASDWPMTP--------------------------------------EPQSLFTSETIP------------------------------VSSSTDWQAAFG---FGSSAKQQ---------------------QQDDDLGFDPFDVTR-------------------KALADLIEKELSVQEHS-------------------PLSP----NPSSHQTGLPNG-----------------------------QQRFPHLQ-HRGLYN---SFSLPQHMAARHPWMGIPTRNNLTHLN-HTATAAAHSHFLDLSMPAQHHSTGLGGIPISENNGSVESINVKEWQDGLRALLPNININFGGLPNSTSSSSSSSTSSVNHIGVPIGSAGISHSLSWDSTASWMDPAIITGIPASTGNSL--DCLQDDNPPHWLKSLQALTEMD----GPPSSSALPQPPHTGLLDAAAHLSLHRAAWAPYLPPPTLTPNQFHSPPPGFQTAFRPQAQTATDILQSAGIDRH---------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "M9PB92-1", "uniprot_id": "M9PB92_DROME", "id": "M9PB92-1", "name": "CCR4-NOT transcription complex subunit 4", "aln": "--------------------MNGLSSNDDAVECPLCMEPLEVDDLTFFPCTCGYQICRFCWHRIRTDE--NKLCPACRKEYPENPADFKPLSQE-------EMIAFKSQKRQRDQQRKQKITENRKHLANVRVVQKNLVFVVGLPPRLADADILKKHE---YFGKYGKIHKVVINPSTTYAGVQV-----RVGPSASAYVTYVNNSDALRAIQSVNNIMIDGRLIKTSLGTTKYCSHFMKNQQCPKGDCMYLHELGDPEASFTKEEMHQGKHLEYEKRLHDTLIASLGPNATGIVNGNGASKANVAIPSSSSASSSSSGSGTNGSSASGNAQQKEAWPSLSVSPINGKEAAATATSSSGKSKREKLRNEKRHEKNKAKNKNGSNTNANASNKENYVPETRSSTSTETFAEATADAPASTKAEPPQASSNRTRADRGKDRTTASAKEQKKSKEAAPAPAASKPAERVETSESTIRQKKAEVTESCEDNLPQKRLAGTNVQRSVSSCSENSEGHVSESSLSEKSLTGDYVEEKCNSVNSESQQESVKFQEELEKSNEAIVEAETILPTAESSEDISPAAVAPGNGEVEGCLPVVDPVEPPSLADNGSRVTDALSKLNIFDDTPSFFTSPSFQQAPILKNKLDLEMRQSHLPDLVNDIDGIQKASNTNEWEEAFKNVMMGNTQHMEEQLLQQQHLQQHQNLRHQLVLQQEEFLRMQELQKRNNFATQINGPANDFLRAYELRAQANAIIQQQLLQQHAGENLFGGNMSKFFDFHKSQPQSHHQYLNGHPPQINGNGAVPEPQRVAASLESNRLNSPFVENGLINSQQQQQQQQQQQKQRMMGMYEFMPPNTQSQQNRFTQNSIVDDDLGFDPFVETQKGLAELMENEVVQKQSINNENPLPKLPPQPQVPPHPQLVDNLQRARMPPPGFNHVNTLGLGGASRLQLTSKIIPFMNMPVNGVGNSGAQGQHQMPMGVNWNAPMGMHQNPGQPVGDSQLQHPMAHNKVYNNSDWTSMDPAILSFRQYSSFPQNQIPPHPQQQQDLFLQHLAQQQNSQSGGFNNQAQQMLPMGMPNSLLNGQQTQPPQVNANVQGMLEFLKSRQFV", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P34909-1", "uniprot_id": "NOT4_YEAST", "id": "P34909-1", "name": "General negative regulator of transcription subunit 4", "aln": "MMNPHVQENLQAIHNALSNFDTSFLSEDEEDYCPLCIEPMDITDKNFFPCPCGYQICQFCYNNIRQNPELNGRCPACRRKYDDENVRYVTLSPEELKMERAKLARKEKERKHREKERKENEYTNRKHLSGTRVIQKNLVYVVGINPPVPYEEVAPTLKSEKYFGQYGKINKIVVNRKTPHSNNTTSEHYHHHSPGYGVYITFGSKDDAARCIAQVDGTYMDGRLIKAAYGTTKYCSSYLRGLPCPNPNCMFLHEPGEEADSFNKRELHN-KQQAQQQSGGTAFT-----------------RSGIHNNISTS----TAGSNTNLLSEN-----------------------------------------------------------------------------FTGTPSPAAMRAQLHHDSHTNAGTP-------------------VLTPAPVPAGSNPWGVTQSATPVTSIN-------------------------------LSKNSSSIN----LPTLNDSLGHHTTPTTEN---------------------------TITSTTTTTNTNATS-----------------------------------------HSHGSKKKQ------------------------------SLAAEEYKDPYD--ALGNAVD----------------------FLDARLHSLSNYQKRP-------------------ISIKSNIIDEETYKKYP-------------------SLFSWDKIEASKKSDN-------------------------------TLANKLVEILAIKPIDY--------TASVVQFLQSVNVGVNDNITITDNTKTPTQPIRLQTVSQQIQPPLNVSTPPPGIFGP--------------------QHKVPIQQQQMGDTS-----------------------------------------------------SRNSSDLLNQLINGRKIIAGN---------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . ::: ****:**::: * .****.******:**::.** : * *****: * :: . : .** * :: :.::::: :::*:: *****:..**:*:***:***: :. :: : ***::***:*:*:* .*.::. .*. ..*:*: ..** *.* *:. :*** :*:: ******* :::. **: :**:*** *: **.*.*:: *: :: : : . :: ..... : .: : : : .. .:* *. ::. : . . :. : . .: .: .. . *. : :. . * . : ::: .: :*.: :. : : . * .: :. . . : :: . : : :. : . . .: . : . * . . :. : : . ", "identical_positions": 95, "similar_positions": 174, "identity": "8.64%" }, { "cls_id": "homologset.agr.MGI:1859086", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A0G2K2M1-1", "uniprot_id": "A0A0G2K2M1_RAT", "id": "A0A0G2K2M1-1", "name": "", "aln": "MSYPQGYLYQPSASLALYSCPAYSTSVISGPRTDELGRSSSGSAFSPYAGSTAFTAPSPGYNSHLQYGADPAAAAAAAFS-YVGSPYDHTPGMAGSLGYHPYAAPLGSYPYGDPAYRKNATRDATATLKAWLNEHRKNPYPTKGEKIMLAIITKMTLTQVSTWFANARRRLKKENKMTWTPRNRSEDEEEEENIDLEKNDEDEPQKPEDKGDLEGPEAGGTEQKAAAG-CERLQGPLSPAGKETEGSLSDSDFKESPSEGRHDDLPRPPRAGEPSPAGPATARLAEDAGPHYPAGAPAPGPHPSAGELPPGSGGSSVIHSPPPPPPPPPAVLAKPKLWSLAEIATSSDKVKDGGGGSEGSPCPPCPGPIGGQTLGGSRASPAPAPARSPSAQCPFPGGTVLSRPLYYTAPFYPGYTNYGSFGHLHGHPGPGPGPTAGPGSHFNGLNQTVLNRADVLAKDPKMLRSQSQLDLCKDSPYELKKGMSDI", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9JKQ4-1", "uniprot_id": "IRX5_MOUSE", "id": "Q9JKQ4-1", "name": "Iroquois-class homeodomain protein IRX-5", "aln": "MSYPQGYLYQPSASLALYSCPAYSTSVISGPRTDELGRSSSGSAFSPYAGSTAFTAPSPGYNSHLQYGADPAAAAAAAFS-YVGSPYDHTPGMAGSLGYHPYAAPLGSYPYGDPAYRKNATRDATATLKAWLNEHRKNPYPTKGEKIMLAIITKMTLTQVSTWFANARRRLKKENKMTWTPRNRSEDEEEEENIDLEKNDEDEPQKPEDKGDLEGPESGGAEQKATAG-CERLQGPLSPAGKETEGSLSDSDFKESSSEGRHDELPRPPRAGESSPAGPATARLAEDAGPHYPASVPAPGPHPSAGELPPGSGGSSVIHSPPPPPPPPPAVLAKPKLWSLAEIATSSDKVKDGGGGSEGSPCPPCPGPMGGQTLGGSRASPAPAPARSPSAQCPFPGGTVLSRPLYYTAPFYPGYTNYGSFGHLHGHPGPGPSPTAGPGSHFNGLNQTVLNRADVLAKDPKMLRSQSQLDLCKDSPYELKKGMSDI", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P78411-1", "uniprot_id": "IRX5_HUMAN", "id": "P78411-1", "name": "Iroquois-class homeodomain protein IRX-5", "aln": "MSYPQGYLYQPSASLALYSCPAYSTSVISGPRTDELGRSSSGSAFSPYAGSTAFTAPSPGYNSHLQYGADPAAAAAAAFSSYVGSPYDHTPGMAGSLGYHPYAAPLGSYPYGDPAYRKNATRDATATLKAWLNEHRKNPYPTKGEKIMLAIITKMTLTQVSTWFANARRRLKKENKMTWTPRNRSEDEEEEENIDLEKNDEDEPQKPEDKGDPEGPEAGGAEQKAASG-CERLQGPPTPAGKETEGSLSDSDFKEPPSEGRLDALQGPPRTGGPSPAGPAAARLAEDPAPHYPAGAPAPGPHPAAGEVPPGPGGPSVIHSPPPPPP--PAVLAKPKLWSLAEIATSSDKVKDGGGGNEGSPCPPCPGPIAGQALGGSRASPAPAPSRSPSAQCPFPGGTVLSRPLYYTAPFYPGYTNYGSFGHLHGHPGPGPGPTTGPGSHFNGLNQTVLNRADALAKDPKMLRSQSQLDLCKDSPYELKKGMSDI", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q1LXU5-1", "uniprot_id": "IRX5A_DANRE", "id": "Q1LXU5-1", "name": "Iroquois homeobox protein 5a", "aln": "MAYPQGYLYQPSASLALYSCPAYSTSVISGPRTEELGRSSSGSAFAPYAGSTAFTSASPGYNSHLPYSAD--AAAAATFTSYVSSPYDHTTGMAGSIGYHPYAAPLGSYPYGDPAYRKNATRDATATLKAWLNEHRKNPYPTKGEKIMLAIITKMTLTQVSTWFANARRRLKKENKMTWTPRNRSEDEEEDENIDLEKNDDDEPNKPTDKGDSTDTEADHKLINPGEIPCDRFKD--ETHSKDLDPPLTDSELKEA--EERTDLLAEQAKPTTSSPS--VLQRGSDLITQEKPS---EPGHAASTGN----SNVTSVIHSPPSAPK--------PKLWSLAEIATSSDRCK---GSSEAS-------QAAGLSQSTVIAS-AASPTRS-SPQCPLPNNTVLSRPIYYTSPFYPGYTNYSTFGHLHSSHGTNTSSTA----HFNGLSQTVLNRAEALVRESK-VRSQTQVDLCKDSPYELKKGMSNI", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*:*******************************:***********:*********:.******** *.** *****:*: **.******.*****:*********************************************************************************************:*********:***:** **** ..*:. :. *:*::. . .*: : .*:**::**. * * * * .:. .**: . * :: . *: ** .::*: .. .*******..* **************: * *..*.* .* : . ** *.:*:** *.***:*..******:***:*********.:*****. *.....*: *****.*******:.*.::.* :***:*:***************:*", "identical_positions": 310, "similar_positions": 88, "identity": "63.79%" }, { "cls_id": "homologset.agr.MGI:1859147", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D4A7E1-1", "uniprot_id": "BATF_RAT", "id": "D4A7E1-1", "name": "Basic leucine zipper transcriptional factor ATF-like", "aln": "MPHSSDSSDSSFSRSPPPG-KQDSSDDVRKVQRREKNRIAAQKSRQRQTQKADTLHLESEDLEKQNAALRKEIKQLTEELKYFTSVLSSHEPLCSVLASGTPSPPEVVYSAH--AFHQPHISSPRFQP", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O35284-1", "uniprot_id": "BATF_MOUSE", "id": "O35284-1", "name": "Basic leucine zipper transcriptional factor ATF-like", "aln": "MPHSSDSSDSSFSRSPPPG-KQDSSDDVRKVQRREKNRIAAQKSRQRQTQKADTLHLESEDLEKQNAALRKEIKQLTEELKYFTSVLSSHEPLCSVLASGTPSPPEVVYSAH--AFHQPHISSPRFQP", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q16520-1", "uniprot_id": "BATF_HUMAN", "id": "Q16520-1", "name": "Basic leucine zipper transcriptional factor ATF-like", "aln": "MPHSSDSSDSSFSRSPPPG-KQDSSDDVRRVQRREKNRIAAQKSRQRQTQKADTLHLESEDLEKQNAALRKEIKQLTEELKYFTSVLNSHEPLCSVLAASTPSPPEVVYSAH--AFHQPHVSSPRFQP", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F1QW76-1", "uniprot_id": "BATF_DANRE", "id": "F1QW76-1", "name": "Basic leucine zipper transcriptional factor ATF-like", "aln": "MAQGSDNNDTSYTKSPSPGNKQGSSDDMRKVMRREKNRIAAQKSRMRQTQKADSLHLESESLEKENAALRKEVKRLTEEAKYLSTVLSNHEPLCTGLSGASP---ELLYGAHHGAFHQ-HISVPHYPL", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*.:.**..*:*:::**.** **.****:*:* ************* *******:******.***:*******:*:**** **:::**..*****: *:..:* *::*.** **** *:* *:: ", "identical_positions": 80, "similar_positions": 34, "identity": "62.5%" }, { "cls_id": "homologset.agr.MGI:1859149", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9H329-1", "uniprot_id": "E41LB_HUMAN", "id": "Q9H329-1", "name": "Band 4.1-like protein 4B", "aln": "MLRFLRRTFGRRSMQRYARGAAGRGAAGLGDERDGGPRGGPAAAASSSALPAAPGGSVFPAGGGPLLTGGAAVHISAAGAAKATLYCRVFLLDGTEVSVDLPKHAKGQDLFDQIVYHLDLVETDYFGLQFLDSAQVAHWLDHAKPIKKQMKIGPAYALHFRVKYYSSEPNNLREEFTRYLFVLQLRHDILSGKLKCPYETAVELAALCLQAELGECELPEHTPELVSEFRFIPNQTEAMEFDIFQRWKECRGKSPAQAELSYLNKAKWLEMYGVDMHVVRGRDGCEYSLGLTPTGILIFEGANKIGLFFWPKITKMDFKKSKLTLVVVEDDDQGREQEHTFVFRLDSARTCKHLWKCAVEHHAFFRLRTPGNSKSNRSDFIRLGSRFRFSGRTEYQATHGSRLRRTSTFERKPSKRYPSR------------------RHSTFKASNPVIAAQLCSKTNPEVHNYQPQYHPNIHP--------------SQPRWHPHSPN---VSYPLPSPVLSSSDRLPFGIEENGGTPFLTAASGRHHHQHQHQHQH-----------------------------QHHSNYSLSLTLENKEGPLRSPNSSSKSLTKLSPGTPALFS---EAAAHLKKLELETVKAAGPWPPLHIN----------------------INKAEEKKVSEKTLQTPLLPSPVADHVKCNILKAQLENASRVNIQGGKEESPFVNINKKSSLQDASVRSPIPIRVETAQPAVEKPEIKPPRVRKLT----RQYSFDEDDLPPDLAEAVGVTT-----STTTNTTTAATQVSVPLPSPKVQNVSSP--HKSEGKGLLSPGAKSPSDRGGAFTLEPGDLLMDFTEATPLAEPASNPHCAHSRCSPPLSLPMKEETTGVCMYPPIKTRLIKTFPVDTMNPFPDTFTTGPQFTADFRDSKLQCCPGPTSPLIPAATLRPLTETVSTVQTIYTTRKPVSLAASAETLRQELEREKMMKRLLMTEL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9JMC8-1", "uniprot_id": "E41LB_MOUSE", "id": "Q9JMC8-1", "name": "Band 4.1-like protein 4B", "aln": "MLRFLRRTFGRRSMQRYARGAAGRGAAGLGDERDGGPRGGPAAAASSSVLPAAPGGSVFPAGGGPLLTGGAAVHISASGAAKATLYCRVFLLDGTEVSVDLPKHAKGQDLFDQIVYHLDLVETDYFGLQFLDSAQVTHWLDHAKPIKKQMKVGPAYALHFRVKYYSSEPNNLREEFTRYLFVLQLRHDILSGKLKCPYETAVELAALCLQAELGECELPEHTPELVSEFRFIPNQTEAMEFDIFQRWKEYRGKSPAQAELSYLNKAKWLEMYGVDMHVVRGRDGCEYSLGLTPTGILIFEGANKIGLFFWPKITKMDFKKSKLTLVVVEDDDQGREQEHTFVFRLDSARTCKHLWKCAVEHHAFFRLRTPSNSKSARSDFIRLGSRFRFSGRTEYQATHGSRLRRTSTFERKPSKRYPSR------------------RHSTFKASNPVIAAQLCSKANPEVHNYQPQYHPDVHP--------------SQPRWRPHSPN---VSN----HSICKQNKPCF---QDDRPHWKTSASGDGSHFDYVQDQN-----------------------------QRNLGGAYSVTYR------------DKLMTAL------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "B2RYE5-1", "uniprot_id": "E41LB_RAT", "id": "B2RYE5-1", "name": "Band 4.1-like protein 4B", "aln": "MLRFLRRTFGRRSMQRYARGAAGRGAAGLGDERDGGPRGGPAAAASSSVLPAAPGGSVFPAGGGPLLTGGAAVHISASGAAKATLYCRVFLLDGTEVSVDLPKHAKGQDLFDQIVYHLDLVETDYFGLQFLDSAQVTHWLDHSKPIKKQMKVGPAYALHFRVKYYSSEPNNLREEFTRYLFVLQLRHDILSGKLKCPYETAVELAALCLQAELGECELPEHTPELVSEFRFIPNQTEAMEFDIFQRWKEYRGKSPAQAELSYLNKAKWLEMYGVDMHVVRGRDGCEYSLGLTPTGILIFEGANKIGLFFWPKITKMDFKKSKLTLVVVEDDDQGREQEHTFVFRLDSARTCKHLWKCAVEHHAFFRLRTPSNSKSARSDFIRLGSRFRFSGRTEYQATHGSRLRRTSTFERKPSKRYPSR------------------RHSTFKASNPVIAAQLCSKTNPEVHNYQPQFHPNVHP--------------SQPRWRPHSPN---VSN----HSTCKQNKPSF---QDDRPHWKASASGDDGHFDYVHDQN-----------------------------QRNLGGAYSVTYR------------DKLMTAL------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0A8M2B4V0-1", "uniprot_id": "A0A8M2B4V0_DANRE", "id": "A0A8M2B4V0-1", "name": "", "aln": "MMGFLRRTFSRRS-KRNARPPS--EVDGTGNVRGG-----------NAVLQAHQQQVIHAP---TVVTGGAVVHIPAAGNSKDAITCRVLLLDGSDVNVELPKHAKGQDLFDQIMYHLDLVEADYFGLQFMDPEQVAHWLDAAKPIKKQIRHGPPYRLFFRVKFYSSEPNNLHEEFTRYLFVLQLRQDILSGKLKCPYDVSVELGAYCLQSELGDCDPLEHSILLVSEFRFSPKQTEIMEADIYRKWVECRGMIPSQAELNFLNKCKWLEMYGVDMHFVKGRDGGEYALGLTPTGILVFEGSSKIGLFFWPKITRLDFKRNRLTLVVVEDDEKGREQEHTFVFQLSSSHECKHLWKCAVESHAFFRLRQPTHNKTSRSDFTRLGSRFRFSGRTEYQATHSGKVRRASTFERRPSKRYPSR------------------AQSMVKAMTPAKHPHLSAQTSPEPS--LKPYKHNIPI--------------AQDPWQRSHPPPSLTSPLYIQPMELGHTPPPHSFPLSAADTRRFSVEENEAPHSGKIHRC-----------------------------YHHHGYEKQEPLC-----------LTTAKPKAWVVSPALSD---ELDRALQN-QLEAEPAA--WPALHIN----------------------IDMAEEKPLSEKSLPS--SPAVLQEQLKSNISKRATQSDS-------------GNSKGNSSSGDQTDRYPSSSQ-DSGSSSLNIEKPRVDRRKRLV----RQFSFNHSDED-DLPEALAAIS-----SQCS------------------MGKSSS--NSSLDKQVQPP-----------------------------------------------------------IYPPQKD-----------------------TSRLEHDSSPLFFPSPVPHLLPYATHTQ----------------------SSEDLR--MEREKLLRALLMTEL", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VFU8-1", "uniprot_id": "Q9VFU8_DROME", "id": "Q9VFU8-1", "name": "Moesin/ezrin/radixin homolog 1", "aln": "MLRFLSRRKVRNNYVDNSREGGGATSSAVG--------------------VAGGGGAITSG-------GSSQIKPQRIVVNKNKIDCRVILLDNTDLSIELSKKALGSFLYEQVFYALDIIEKDYFGLQFMDANHVKHWLDPTKPIKKQVKIGPPYTFRLKVKFYSSEPNTLREELTRYLFFLQLKQDLLEGRLDCPEDKATELCALALQSELGDYDNQEHSAATVSEFRFVPEQTEDLEIAILDEYKTCRGLTPAQAETAFLNKAKWLDMYGVDMHTVLGKDGCEYHLGLTPTGILVFERDQKIGLFFWPKISKLDFKKKKLTLIVIEDDDEGREQEHTFVFRLYNEKACKHLWKCAVEHHTFFRLRAPVKGPSARQNFFRMGSRFRYSGRTEFQTTQQSRARRTVQFERRPSQRFASRQSHLLRERQKASQEAAVSAVASVNARAAAAAAAAAASQSPAPATPLVSSQVSTPTPNNDNNNDAFDSLISTDQFITVTPSPSVLTVIQNSAIIEPDAACSGSISSSSQAAANFASLGRNSLKSNFSNEDPAYSKIGSIGKASGLTVKLDPDYTPPYSPNATKNFDETNPFRNATSSHHGSFGKASISSGQLSVKSGLSDKDRELDSLLKSIVKDPSPSVLANEAINDANSIRVTINKTFDMDHNTETLKRLSNANEKPNNQVKLANVNTTALPPGNIKCNILKARVEEELGAGGNAKLTNQMFVPAAHSSNMHTSNTNSSNNHAHSDGPDSLNATYISVGGDKLTLSIPEQKPSTGSSSSSSTSSTATTTTNGNGPYSNATFVSGFSAPLTPPSSLPANLNNTGSGCNTTLTSVTTISTPSSPTATVSTTASESVAPALSNASAAEILINEIFINNIINNNASGSITAETAAKPAGSSTPSAGTLLFSTLSEQERLESQKTNQQMNQSLNLNQNHSEVDAP-PSEKKTPSNYPDSSRIPFPSSSNSKDMVSPWLVSSEVVSAPKGRESAIIRKSVITTQL", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*: ** * *.. :* . . * * : . *.: :: * : ***:***.:::.::*.*:* *. *::*:.* **::* *******:*. :* **** :******:: **.* : ::**:******.*:**:*****.***::*:*.*:*.** : :.** * .**:***: : **: ****** *:*** :* * .: ** *:*** :***.***:******* * *:** ** *********:** .**********:::***:.:***:*:***::**********:* . : ********** *:***** * :. : *.:* *:*****:*****:*:*: .: **: ***:**:*:.** : .:* .. . .:. .* : . : : * : . : .. . . . . ", "identical_positions": 207, "similar_positions": 124, "identity": "20.7%" }, { "cls_id": "homologset.agr.MGI:1859150", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q6JP77-1", "uniprot_id": "AKA7G_RAT", "id": "Q6JP77-1", "name": "A-kinase anchor protein 7 isoforms delta and gamma", "aln": "MERPAAGEIDANKCDHLSRGEEGTGDLETSPVGSLADLPFAAVDIQDDCGLPDVPQGNVPQGNPKRSKENRGDRNDHVKKRKKAKKDYQPNYFLSIPITNKKITAGIKVLQNSILRQDNRLTKAMVGDGSFHITLLVMQLLNEDEVNIGTDALLELKPFVEEILEGKHLTLPFHGIGTFQGQVGFVKLADGDHVSALLEIAETAKRTFQEKGILAGESRTFKPHLTFMKLSKAPMLWKKGVRKIEPGLYEQFIDHRFGEEILYQIDLCSMLKKKQSNGYYHCESSIVIGEKDRKEPEDAELVRLSKRLVENAVLKAVQQYLEETQNKKQPGEGNSVKAEEGDRNGDGSDNNRK", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q7TN79-1", "uniprot_id": "AKA7G_MOUSE", "id": "Q7TN79-1", "name": "A-kinase anchor protein 7 isoform gamma", "aln": "-------------------------------------MPFAAVDIQDDCGSPDVPQANPKR--SKEEEEDRGDKNDHVKKRKKAKKDYQPNYFLSIPITNKKITTGIKVLQNSILQQDKRLTKAMVGDGSFHITLLVMQLLNEDEVNIGTDALLELKPFVEEILEGKHLALPFQGIGTFQGQVGFVKLADGDHVSALLEIAETAKRTFREKGILAGESRTFKPHLTFMKLSKAPMLRKKGVRKIEPGLYEQFIDHRFGEELLYQIDLCSMLKKKQSNGYYHCESSIVIGEKDRREPEDAELVRLSKRLVENAVLKAVQQYLEETQNKKQPGEGNSTKAEEGDRNGDGSDNNRK", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9P0M2-1", "uniprot_id": "AKA7G_HUMAN", "id": "Q9P0M2-1", "name": "A-kinase anchor protein 7 isoform gamma", "aln": "MERPEAGGINSNECENVSRKKKMSEEFEANTMDSLVDMPFATVDIQDDCGITDEPQINLKR-----SQENEWVKSDQVKKRKKKRKDYQPNYFLSIPITNKEIIKGIKILQNAIIQQDERLAKAMVSDGSFHITLLVMQLLNEDEVNIGIDALLELKPFIEELLQGKHLTLPFQGIGTFGNQVGFVKLAEGDHVNSLLEIAETANRTFQEKGILVGESRSFKPHLTFMKLSKSPWLRKNGVKKIDPDLYEKFISHRFGEEILYRIDLCSMLKKKQSNGYYHCESSIVIGEKNGGEPDDAELVRLSKRLVENAVLKAVQQYLEETQNKNKPGEGSSVKTEAADQNGNDNENNRK", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :***:******** .* ** * : .:*:. :.*:****** :****************:* ***:***:*::**:**:****.********************** *********:**:*:****:***:***** .********:****.:********:***:*****.****:************:* * *:**:**:*.***:**.******:**:***************************: **:******************************::****.*.*:* .*:**:..:****", "identical_positions": 239, "similar_positions": 55, "identity": "67.71%" }, { "cls_id": "homologset.agr.MGI:1859152", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P97570-1", "uniprot_id": "PLPL9_RAT", "id": "P97570-1", "name": "85/88 kDa calcium-independent phospholipase A2", "aln": "------MQFFGRLVN--TLSSVTNLFSNPFRVKEVSLADYASSERVREEGQLILLQ------NASNRTWDCVLVSPRNPQ--SGFRLFQLESEADALVNFQQYSSQLPPFYESSVQVLHVEVLQHLTDLIRNHPSWTVTHLAVELGIRECFHHSRIISCANSTENEEGCTPLHLACRKGDSEILVELVQYCHAQMDVTDNKGETAFHYAVQGDNPQVLQLLGKNASAGLNQVNNQGLTPLHLACQMGKQEMVRVLLLCNARCNIMGPGGFPIHTAMKFSQKGCAEMIISMDSNQIHSKDPRYGASPLHWAKNAEMARMLLKRGCDVDSTSASGNTALHVAVTRNRFDCVMVLLTYGANAGARGEHGNTPLHLAMSKDNMEMVKALIVFGAEVDTPNDFGETPAFIASKISKLITRKALLTLLKTVGADYHFPFIQGVSTEQSSAAGPHPFFSLDRTQPPTISLNNLELQDLMPVSRARKPAFILSSMR-------------------------------------------------------------------------------DEKRSHDHLLCLDGGGVKGLVIIQLLIAIEKASGVATKDLFDWVAGTSTGGILALAILHSKSMAYMRGVYFRMKDEVFRGSRPYESGPLEEFLKREFGEHTKMTDVKKPKVMLTGTLSDRQPAELHLFRNYDAPEAVREPRCTPNINLKPPTQPA-------------------------DQLVWRAARSSGAAPTYFRPNGRFLDGGLLANNPTLDAMTEIHEYNQDMIRKGQGNKVKKLSIVVSLGTGKSPQVPVTCVDVFRPSNPWELAKTVFGAKELGKMVVDCCTDPDGRAVDRARAWCEMVGIQYFRLNPQLGSDIMLDEVSDAVLVNALWETEVYIYEHREEFQKLVQLLLSP", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P97819-1", "uniprot_id": "PLPL9_MOUSE", "id": "P97819-1", "name": "85/88 kDa calcium-independent phospholipase A2", "aln": "------MQFFGRLVN--TLSSVTNLFSNPFRVKEVSLTDYVSSERVREEGQLILLQ------NVSNRTWDCVLVSPRNPQ--SGFRLFQLESEADALVNFQQFSSQLPPFYESSVQVLHVEVLQHLTDLIRNHPSWTVTHLAVELGIRECFHHSRIISCANSTENEEGCTPLHLACRKGDSEILVELVQYCHAQMDVTDNKGETAFHYAVQGDNPQVLQLLGKNASAGLNQVNNQGLTPLHLACKMGKQEMVRVLLLCNARCNIMGPGGFPIHTAMKFSQKGCAEMIISMDSNQIHSKDPRYGASPLHWAKNAEMARMLLKRGCDVDSTSSSGNTALHVAVMRNRFDCVMVLLTYGANAGARGEHGNTPLHLAMSKDNMEMVKALIVFGAEVDTPNDFGETPALIASKISKLITRKALLTLLKTVGADHHFPIIQGVSTEQGSAAATHPLFSLDRTQPPAISLNNLELQDLMPISRARKPAFILSSMR-------------------------------------------------------------------------------DEKRSHDHLLCLDGGGVKGLVIIQLLIAIEKASGVATKDLFDWVAGTSTGGILALAILHSKSMAYMRGVYFRMKDEVFRGSRPYESGPLEEFLKREFGEHTKMTDVKKPKVMLTGTLSDRQPAELHLFRNYDAPEAVREPRCNQNINLKPPTQPA-------------------------DQLVWRAARSSGAAPTYFRPNGRFLDGGLLANNPTLDAMTEIHEYNQDMIRKGQGNKVKKLSIVVSLGTGKSPQVPVTCVDVFRPSNPWELAKTVFGAKELGKMVVDCCTDPDGRAVDRARAWCEMVGIQYFRLNPQLGSDIMLDEVSDAVLVNALWETEVYIYEHREEFQKLVQLLLSP", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O60733-1", "uniprot_id": "PLPL9_HUMAN", "id": "O60733-1", "name": "85/88 kDa calcium-independent phospholipase A2", "aln": "------MQFFGRLVN--TFSGVTNLFSNPFRVKEVAVADYTSSDRVREEGQLILFQ------NTPNRTWDCVLVNPRNSQ--SGFRLFQLELEADALVNFHQYSSQLLPFYESSPQVLHTEVLQHLTDLIRNHPSWSVAHLAVELGIRECFHHSRIISCANCAENEEGCTPLHLACRKGDGEILVELVQYCHTQMDVTDYKGETVFHYAVQGDNSQVLQLLGRNAVAGLNQVNNQGLTPLHLACQLGKQEMVRVLLLCNARCNIMGPNGYPIHSAMKFSQKGCAEMIISMDSSQIHSKDPRYGASPLHWAKNAEMARMLLKRGCNVNSTSSAGNTALHVAVMRNRFDCAIVLLTHGANADARGEHGNTPLHLAMSKDNVEMIKALIVFGAEVDTPNDFGETPTFLASKIGRLVTRKAILTLLRTVGAEYCFPPIHGVPAEQGSAAPHHP-FSLERAQPPPISLNNLELQDLMHISRARKPAFILGSMR-------------------------------------------------------------------------------DEKRTHDHLLCLDGGGVKGLIIIQLLIAIEKASGVATKDLFDWVAGTSTGGILALAILHSKSMAYMRGMYFRMKDEVFRGSRPYESGPLEEFLKREFGEHTKMTDVRKPKVMLTGTLSDRQPAELHLFRNYDAPETVREPRFNQNVNLRPPAQPS-------------------------DQLVWRAARSSGAAPTYFRPNGRFLDGGLLANNPTLDAMTEIHEYNQDLIRKGQANKVKKLSIVVSLGTGRSPQVPVTCVDVFRPSNPWELAKTVFGAKELGKMVVDCCTDPDGRAVDRARAWCEMVGIQYFRLNPQLGTDIMLDEVSDTVLVNALWETEVYIYEHREEFQKLIQLLLSP", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AC58IDZ9-1", "uniprot_id": "A0AC58IDZ9_DANRE", "id": "A0AC58IDZ9-1", "name": "phospholipase A2", "aln": "MNRLVTMQFLGRILD--TVSSVSSLFSNPYRVRDVQLSDYNGKILHQQEGRLALYR------NQQSQSWDCLLLCPESPS--VALRMFQVASEEDAMNWFPQYALKLRPFYEMLRPPLKPEMLQPIVDCVRNHPDWSSAHIAVDTGLRDCLKHNYILSQMNSRD-AQGQTPLHLACERGDVGCVRELLEECQARTDVKDKNGETPMHCAAKQDSALIIEVLCAQLCAGVNELNAAGETPMHIACRLGRVEVVKGLLGGGARCDIMGNNGFPIHTAMKFSEKSCAEAILSSSPNQLLAEDPVYGGTPLHWAKTAEMSRLLLDRGCNVNYLSKTGESPLHILTKRGRFEAAMTLLTHGADANIRGQDGNTALHLAMKLDNMDLIKALMVFGADVEVHNDVGETPGLIAARTSKGSNRKVLLNMLCSVGVERCHPPSLNSPT-----------HSLRKAPPPGIGFDDIMQVAVAVTAMSRG--FVEADGL-------------------------------------------------------------------------------KTGNKMDRLLCLDGGGIKGLVLIQLLIALEKEAGRPIRELFDWVSGTSTGGILALAIVHGKSMEYLRCLYFRMKEQVFKGSRPYESGPLEEFLKNEFGENTKMTDVTHPRVMVTSVLADRHPGELHLFRNYDPPALQRDPPYKSTATFQPLTVPQGWEDEDLLLVGYTRPPRKRRKVTDEEQLVWRAARSSGAAPTYFRPMGRFLDGGLLANNPTLDAMTEIHQFNKALKAQGRDEDVTRLGVVVSLGTGKPPQVAVNSVDVFRPSNPIELAKTFVGVKELGKMLVDCCTDSDGCAVDRARAWCEMADINYHRLSPQLSQEVMLDEVSDAVLVDMLWETQMYLYEHRDVIQTLCQQLLQL", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q7KUD4-1", "uniprot_id": "Q7KUD4_DROME", "id": "Q7KUD4-1", "name": "phospholipase A2", "aln": "----MAWMALGALASGFVLQRLLGVDQPANKVVEIKSEALGTLQVLARDDAMLLFAPPFNSSNEKRAVYEIILQRPTSDSNTTSFSLYRSPVQQEAEERFNAFLQRLPVFVSIVKEYYNVNGLQKACDALADNPSWTLSHLIAYFNLVDYISNPKMLQCVDQADAATLMSPFQLAIKQGHMEMVKALLP--LSKLEHLDINSNSVFHYAAS-TTKEIINLIIDKSTVNLNHLNSDGYTPLHVACLADKPENVKALLLAGANVNLNAKD---IRKVYKTSAPTTVSSFLRTNVSKLYTQDMKYGGTPLHWCSSRETLHALIMEGCDVNATNFDGRTALHVMVARNRFECVVTLLAHDAEIDVLDKDGNAALHIAIEKKLVPIVQCLVVFGCDINLKNKDGKTPRHMVGNDASGNKDDEILYILHSVGAKRCKDTGSKCPPG---CNAKGNYNGIPPEAPESVEQREHIEHMLATTSRQMMGGFLNAAANGILEKQQPAQKPVVVDTEKELKGQSIMDALLGMFTTKVNADEMKKENSSDSLASGSQKSAVSSPEQLPSPTSPIAAEIGDKPYGRGRLLCLDGGGIRGLVLVQMLLEIEKLSRTPIIHMFDWIAGTSTGGILALALGCGKTMRQCMGLYLRMKEQCFVGSRPYNSEFFESILKDNLGEFNVMTDIKHPKIMVTGVMADRKPVDLHLFRNYTSASDILGIVTPINNRRIPPPQPS-------------------------EQLVWRAARATGAAPSYFRAFGRFLDGGLIANNPTLDAMTEIHEYNMALRSAGRESEAIPVSVVMSLGTGHIPVTELKDIDVFRPESIWDTAKLAYGISTIGNLLVDQATCSDGRVVDRARAWCSTIGIPYFRFNPQLSEDIAMDEKDDQKLINMLWHTKAYMHANRNKIIEMINFLK--", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :* : . ... : .: . . :* :: .:. : * * :: :* * . . .: ::: : :* * : :* * . : : ** * : ::*.*: :*: . .: : : : ::. : : :*::** .:*. : *: :: : * :.:: :* *.. . ::::: : ..:*.:* * **:*:** .: * *: ** .*. :: . . *:.. * * .. :: . .:: ::* **.:****... * : *: .**:*: . *.:.**: . *.**:..:.**::.*: . .:.**:.**:*:. . : :::.*:***.::: *. *:** :... . . . :* :* :**.. .. .: * : : : : *: . . .:********::**:::*:*: :** : . .:***::***********: .*:* :*:***:: * *****:* :*.:** ::** . ***: :*::*:*..::**:* :******* .. . * . * :********::****:***. ********:*************::* : *: ... :.:*:*****: * . :. :*****.. : ** * . :*:::** .* .** .********. .* *.*:.***. :: :** .* *:: **.*: *:: :*: : : : * ", "identical_positions": 227, "similar_positions": 277, "identity": "24.49%" }, { "cls_id": "homologset.agr.MGI:1859158", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8CCS6-1", "uniprot_id": "PABP2_MOUSE", "id": "Q8CCS6-1", "name": "Polyadenylate-binding protein 2", "aln": "MAAAAAAAAAAGAAGGRGSGPGRRRHLVPGAGGEAGEGDPGGAGDYGNGLESEELEPGELL----PEPEPEEEPPRPRAPPGAPGPGPGSGAPGSQEEEEEPGLVEADPGDGAIEDPELEAIKARVREMEEEAEKLKELQNEVEKQMNMSPPPGNAGPVIMSLEEKMEADARSIYVGNVDYGATAEELEAHFHGCGSVNRVTILCDKFSGHPKGFAYIEFSDKESVRTSLALDESLFRGRQIKVIPKRTNRPGIS----TTDRGFPRSRYRARTTNYNSSRSR-FYSGFNSRPRGRIYRGRARATSWYSPY-----------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "G3V7Z8-1", "uniprot_id": "G3V7Z8_RAT", "id": "G3V7Z8-1", "name": "Polyadenylate-binding protein 2", "aln": "MAAAAAAAAAAGAAGGRGSGPGRRRHLVPGAGGEAGEGDPGGAGDYGNGLESEELEPGELL----PEPEPEEEPPRPRAPPGAPGPGPGSGAPGSQEEEEEPGLVETDPGDGAIEDPELEAIKARVREMEEEAEKLKELQNEVEKQMNMSPPPGNAGPVIMSLEEKMEADARSIYVGNVDYGATAEELEAHFHGCGSVNRVTILCDKFSGHPKGFAYIEFSDKESVRTSLALDESLFRGRQIKVIPKRTNRPGIS----TTDRGFPRARYRARTTNYNSSRSR-FYSGFNSRPRGRIYRGRARATSWYSPY-----------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q86U42-1", "uniprot_id": "PABP2_HUMAN", "id": "Q86U42-1", "name": "Polyadenylate-binding protein 2", "aln": "MAAAAAAAAAAGAAGGRGSGPGRRRHLVPGAGGEAGEGAPGGAGDYGNGLESEELEPEELLLEPEPEPEPEEEPPRPRAPPGAPGPGPGSGAPGSQEEEEEPGLVEGDPGDGAIEDPELEAIKARVREMEEEAEKLKELQNEVEKQMNMSPPPGNAGPVIMSIEEKMEADARSIYVGNVDYGATAEELEAHFHGCGSVNRVTILCDKFSGHPKGFAYIEFSDKESVRTSLALDESLFRGRQIKVIPKRTNRPGIS----TTDRGFPRARYRARTTNYNSSRSR-FYSGFNSRPRGRVYRGRARATSWYSPY-----------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q7KNF2-1", "uniprot_id": "PABP2_DROME", "id": "Q7KNF2-1", "name": "Polyadenylate-binding protein 2", "aln": "-----------------------------------------------MADEDITLNEDQLL-------ESLEETN-------------GEQETEIATEVEEEGSMQIDP--------ELEAIKARVKEMEEEAEKIKQMQSEVDKQMAGGSTTG-LATVPLSLEEKQEIDTRSVYVGNVDYGASAEELEAHFHGCGTINRVTILCNKADGHPKGFAYIEFGSKEFVETALAMNETLFRGRQIKVMSKRTNRPGLS----TTNR-FARGSFRGRGAR--VSRAC-CHSTFRGARRAMGYRGRA---NYYAPY-----------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P40561-1", "uniprot_id": "SGN1_YEAST", "id": "P40561-1", "name": "RNA-binding protein SGN1", "aln": "----------------------------------------------------------------------------------------------MSQEEKVDAKAT------------LKTEISNNKKNDKQELELDELVGKLS--IEGTPQVSQKLSKEEKHAHQLEADSRSIFVGNITPDVTPEQIEDHFKDCGQIKRITLLYDRNTGTPKGYGYIEFESPAYREKALQLNGGELKGKKIAVSRKRTNIPGFNRHYNSQNQYFQQWQWNYPLMAYPNPDTFPYYPPYPPNQSPNQNFGYNKNNYYRSPYNNKNRTFQKKHFNSAKDSTKNIRSTSQKPVVMPSDNVKSSTQEKDSK", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * : . *:: :. :: ::: ::.:: .::. : . . . . .: * *:**::***: ..:.*::* **:.** ::*:*:* :: * ***:.**** . ..:* :: ::*::* * **** **:. : :: * : :. . : :. : * : :** ", "identical_positions": 40, "similar_positions": 72, "identity": "11.17%" }, { "cls_id": "homologset.agr.MGI:1859162", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q5XI59-1", "uniprot_id": "RNF10_RAT", "id": "Q5XI59-1", "name": "E3 ubiquitin-protein ligase RNF10", "aln": "-MPQSSPSTAATASDMDKNSGSNSSSASSGSSKGQQPPRSASAGP-AGESKPKSDGKNSNGSKRYNRKREPSYPKNENFSNQSRRSNSQKSKTFNKTPPQRGGGSSKPFSSSSNGGRRDEVAEAQRAEFSPAQFSGPKKINLNHLLNFTFEPRGQAGHFE--GSGHGSWGKRNKWG--HKPFNKELFLQANCQFVVSEDQDYTANFADPDTLVNWDFVEQVRICSHEVPSCPICLYP-PTAAKITRCGHIFCWACILHYLSLSE------------RTWSKCPICYSSVHKKDLKSVVATE-------SRQYVVGDTITMQLMKREKGVLVALPKSK---WMNVDHPISLGDEQHSQYSKLLLASKEQVLHRVVLEEKVALEQQLAEEKHTPESCFIEAALQEVKIREEALSGVAGGRAEVTGVVTALEQLVLMAPLAKESAFQPRKGVLEYLSAFDEEAAQVCSLDPPG-PLALPLVEEEEAVSEPE------ACED-LIADDSLGEGTVCAELSQEEPIAKPGFTQLSSSPCYYFYQAEDGQHMFLHPVNVRCLVREYGSLEQSPEKISATVVEIAG-YSMSEDVRQRHRYLSHLPLTCEFSICELALQP-PVVSKETLEMFSDDIEKRKR----QRQKKAREERRRERRIELEENKRQGR--YPEVHIPLENLQQFPAFNSYTCSSDSALGPTSTEGHGALSLSPLSRSPGSHADFLLTPLSPTASQGSPSFCVGSLEEDSPFLSFAQMLRVGKAKADGWPKAAPKKDDNSLAPPAPVDSDGESDNSDRVPVPSFQNSFSQAIEAAFMKLD----TPATSDPLS-DRGGRKRKRQKQKLLFSTSVVHTK", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q3UIW5-1", "uniprot_id": "RNF10_MOUSE", "id": "Q3UIW5-1", "name": "E3 ubiquitin-protein ligase RNF10", "aln": "-MPQSSPSAAATASDMDKNSGSNSSSASSGSSKGQQPPRSASAGP-AGESKPKSDGKNSNGSKRYNRKREPSYPKNENFSNQSRRSNSQKSKTFNKMPPQRGGGSSKPFSSSSNGGRRDEVAEAQRAEFSPAQFSGPKKINLNHLLNFTFEPRGQAGHFE--GSGHGGWGKRNKWG--HKPFNKELFLQANCQFVVSEDQDYAAHFADPDTLVNWDFVEQVRICSHEVPSCPICLYP-PTAAKITRCGHIFCWACILHYLSLSE------------KTWSKCPICYSSVHKKDLKSVVATE-------SRQYAVGDTITMQLMKREKGVLVALPKSK---WVNVDHPINLGDEQLSQYSKLLLASKEQVLHRVVLEEKGALEQQLAEEKHTPESCFIEAAIQEVKIREEALSGVAGGGGEVTGVVAALEHLVLMAPLATESAFQPRKGVLEYLSAFDDEAAQVCSLDPPG-PLALPLVEEEEAVSEPE------ACEDAEVADDSLGEGTVGPEMSQEEPITKPGFTQLSSSPCYYFYQAEDGQHMFLHPVNVRCLVREYGSLEQSPEKISATVVEIAG-YSMSEDVRQRHRYLSHLPLTCEFSICELALQP-PVVSKETLEMFSDDIEKRKR----QRQKKAREERRRERRIEMEENKRQGR--YPEVHIPLENLQQFPAFNSYTCPSDSALGPTSTEGHGALSLSPLSRSPGSHADFLLTPLSPTASQGSPSFCVGSLEDDSPFLSFAQMLRVGKAKADGWPKTAPKKDDNSLVPPAPVDSDGESDNSDRVPVPSFQNSFSQAIEAAFMKLD----TPATSDPLSEDRGGKKRKRQKQKLLFSTSVVHTK", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8N5U6-1", "uniprot_id": "RNF10_HUMAN", "id": "Q8N5U6-1", "name": "E3 ubiquitin-protein ligase RNF10", "aln": "-MPLSSPNAAATASDMDKNSGSNSSSASSGSSKGQQPPRSASAGP-AGESKPKSDGKNSSGSKRYNRKRELSYPKNESFNNQSRRSSSQKSKTFNKMPPQRGGGSSKLFSSSFNGGRRDEVAEAQRAEFSPAQFSGPKKINLNHLLNFTFEPRGQTGHFE--GSGHGSWGKRNKWG--HKPFNKELFLQANCQFVVSEDQDYTAHFADPDTLVNWDFVEQVRICSHEVPSCPICLYP-PTAAKITRCGHIFCWACILHYLSLSE------------KTWSKCPICYSSVHKKDLKSVVATE-------SHQYVVGDTITMQLMKREKGVLVALPKSK---WMNVDHPIHLGDEQHSQYSKLLLASKEQVLHRVVLEEKVALEQQLAEEKHTPESCFIEAAIQELKTREEALSGLAGSRREVTGVVAALEQLVLMAPLAKESVFQPRKGVLEYLSAFDEETTEVCSLDTPSRPLALPLVEEEEAVSEPEPEGLPEACDDLELADDNLKEGTICTESSQQEPITKSGFTRLSSSPCYYFYQAEDGQHMFLHPVNVRCLVREYGSLERSPEKISATVVEIAG-YSMSEDVRQRHRYLSHLPLTCEFSICELALQP-PVVSKETLEMFSDDIEKRKR----QRQKKAREERRRERRIEIEENKKQGK--YPEVHIPLENLQQFPAFNSYTCSSDSALGPTSTEGHGALSISPLSRSPGSHADFLLTPLSPTASQGSPSFCVGSLEEDSPFPSFAQMLRVGKAKADVWPKTAPKKDENSLVPPAPVDSDGESDNSDRVPVPSFQNSFSQAIEAAFMKLD----TPATSDPLSEEKGGKKRKKQKQKLLFSTSVVHTK", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "B0UXR5-1", "uniprot_id": "B0UXR5_DANRE", "id": "B0UXR5-1", "name": "E3 ubiquitin-protein ligase RNF10", "aln": "MLESSEALTPEFGLNMEKNPNANNNSSST-----KIPPRSSSTGLNPTDSKAKTDGKNNGGSKRYSRKREPTFAKAESFPG-PRRSQPQKNKNFDKRPPQRGGAGVRQYG-LAGGGRREEVAENRRAEFSPAQFAGPKKISLNHLLNFTFEPRG--GHFGSGGDGHSCWGRRNKWGHKHKPFNKELFLQANCQFVVSDDQDYQAHFTDPDTLVDWDCVQQVRIYSHEVPSCPICLYP-PVAAHMTRCGHIYCWPCMLHYLSLSE------------KSWSKCPICYEAVHSADLKSVVAME-------TRQYVSGNSITMCLMRREKGSLVALPSSQ---WVKVEEPIQFGDVQFCSYSKLLLASRQQVLG-LLAEERMALQTQLSQEKDDPQACFIQSALLQLQEREESL--LKRRRRKTAGSVDGVD----MRKLSLSEQSSPEVTVVNNLTNSKPILQYASAFDDEVQDAQEEVLEEMTNPSVHE-------------APEEIPDGDVEDLPVEETPQSSQ---TAHHGPYYYFYQAEDGQQMFLHPVNVRCLQRQYGSLENSPQTITANVVEIDG-QTVTEDIRRRHRYLSHLPLTCEFSLCELDLQP-PILSKETLDSFADDIEKRKR----LRQKKVRDEKRREKRIEMEENRKQGK--YPEVHIGLENLHHFPAFGSPPQNGPQLHLPEVLLGP----PSPLSSSPSSDG-----VMFPNLSEHSPSLSVVGVEEDSHCMSFAQMLKGGKARVDTGPKTTPKKADMFLAPPA-ADSDGESDNSDRVPVPSFQNSFSQALGQALSKLDNGNQTPAPALPISDDKGGKKKKK-KQKLLFSTSMVHTK", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9W0D8-1", "uniprot_id": "Q9W0D8_DROME", "id": "Q9W0D8-1", "name": "E3 ubiquitin-protein ligase RNF10", "aln": "-----------MDSNNSSNSKKQPQSSHHGKSSSAESQRKSSELHTNSNKQRHSRRRNQVPTPRNDQQQQPQQP-AKLRPNVDKRPKARGFGGGYDFPSPRGQDGASGSSRLAYSATGYSRSGDFDHELNSVYTQGSKKQNLNHLLNFHCVPRELERGHHHQAQQHHGLSGR------KQRYNKEQFLQANFQFVIRSGAKAQVNGS-PDALIDWSYIEQINIQTTEELQCPICLYP-PVAAKLTRCGHAYCWPCLLHYLSLSD------------KTWRKCPICYDAIHAGDLKSCTIEQ-------LRDLQVGEKITFQLMRRRKGSMYIENHVAGLGETIERFPFVSAGEEAKRYSKFLIAKRMDVAAIIERERN---ELLAESDVSCPEDVFIQQALVMLQERVEKLG-----------------------------------------------VEKPDPKEDEEETAPVLCLETETKIDIEK------------SDDASISSGEASSSLSYSS----------NHNKYYYFYQSNDGQNIYLHPLNVKMLQACYGTLDLGPLLIEAQIVQMEQ-HSMDEEHRRKFTCLGHLPLTCQFSVVEVELQP-PVVTGGILKLFKEDILHRKK----ERQRRDREERKREQHINEINDRQMGKLIASAANLDLSSSHEFPTCG----FEEALPAPSGSVPMNISNQDPGSRYSSVTLGSPKQEMWPTIGSNSPGGGGAPLD----------------VQVGAWGRSAPPPPRAVMVPRTSDEDFEQRS----VGHWGLGELLVGALDQKKQKVG---AAKSNGAAPAESKKQKKAKGKKMVPLFATGMNRAP", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q06436-1", "uniprot_id": "MAG2_YEAST", "id": "Q06436-1", "name": "E3 ubiquitin-protein ligase MAG2", "aln": "--------------MVEPDMQKKASGGSGGSEMDTLNATSNSSKQGVSNNKRNPVSKKKPGNKVSDGRDN-----AHNYHGEGRRKSSKQ---------QRSRTPYKETSTRINDQDIDLSIQEEILGGNFKLRGRKTQVSINHLLNFQLPEVEREKSRS--SSSKKSNRRRDE----HVHLHGDTFVNVNYRLLVDDRFDYPEQNCNPNVPVDQEKILRVIVP--KGQNCSICLSEEPVAPRMVTCGHIFCLSCLLNFFSIEETVKNKETGYSKKKKYKECPLCGSIIGPKRVKPVLYEDDFDVTRLNQKPEPGATVHLQLMCKPHGSLLPLPVAL------HLDPLKCGNFPPANLGSIKHYAHIMKCGVSYSLELYQKDIVAIQEQYEIDKAIYNDSGKFVKQSIENIN------------------------------------------------DQISTLLAATTDLSPLSNDINNGLDNFH------------FDDDLLTKYDDSS------------------AYFFYQTLVASSTKYFLSPLDVKILLTIFHYYSKFPESIETTVENIHYDTVVTEQLIRRYKYIGHLPIGTEIALLDLDWRKIPFLPKEIYEQFAHELKQRRRKFTMKKQKEDKEKKLYEKRLEQEHAEFYRK----------ENGNSLKFEDSVQMATHYESIVSSSIPLNSLGISMLGP--------------PTNSCSTPQ------------------------------KQAPSHTKRTIWGTSIAVTEDEKAS---KENKEFQDMLLQRIRQE-DSSD----VTDSTDSPPTSNGKRGRKKKGKVMLFSSNHQALG", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . : : ... . * :.: :. ::. . . : : . . :* ..: *. . . . .: .:****** .. : * : : : *::.* :::: . . : *:. :: . : :: : : .*.*** *.*.::. *** :* .*:*:::*:.: :.: :**:* . : :*. : :. * .: : ** : :* : *: .. ..: : . : .: : : : : :: * : . : . . : . :* .. : :* *::*: * : . * * : : :: : *: ::. :.***: :::: :: : *.:. . * .:: :*:: :*:. :::: *:::: . . : .. : : . . . *. . :* : :* : : : : : : : . . . . . .. : * **::. ", "identical_positions": 58, "similar_positions": 200, "identity": "6.81%" }, { "cls_id": "homologset.agr.MGI:1859165", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8VHX0-1", "uniprot_id": "CCG3_RAT", "id": "Q8VHX0-1", "name": "Voltage-dependent calcium channel gamma-3 subunit", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MRMCDRGIQMLITTVGAFAAFSLMTIAVGTDYWLYSRGVCRTKSTSDNETSRKNEE-----VMTHSGLWRTCCLEGAFRG---VCKKIDHFPED--ADYEQDTAEYLLRAVRASSVFPILSVTLLFFGGLCVAASEFHRSRHSVILSAGIFFVSAGLSNIIGIIVYISANAGDPGQRDSKKS--------YSYGWSFYFGAFSFIIAEIVGVVAVHIYIEKHQQ-------------------------------------------------------------------------------------------------------------------------LRARSHSELLKKSTFARLPPYRYRFRRR-----------------------------------------------------------SSSRSTEPRSRDLSPISK-GFHTIPSTDISMFTLSRDPSKLTMG------TLLNSDRDHAFLQFHN--------------STPKEFKESLHNNPANRRTTPV----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9JJV5-1", "uniprot_id": "CCG3_MOUSE", "id": "Q9JJV5-1", "name": "Voltage-dependent calcium channel gamma-3 subunit", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MRMCDRGIQMLITTVGAFAAFSLMTIAVGTDYWLYSRGVCRTKSTSDNETSRKNEE-----VMTHSGLWRTCCLEGAFRG---VCKKIDHFPED--ADYEQDTAEYLLRAVRASSVFPILSVTLLFFGGLCVAASEFHRSRHSVILSAGIFFVSAGLSNIIGIIVYISANAGDPGQRDSKKS--------YSYGWSFYFGAFSFIIAEIVGVVAVHIYIEKHQQ-------------------------------------------------------------------------------------------------------------------------LRARSHSELLKKSTFARLPPYRYRFRRR-----------------------------------------------------------SSSRSTEPRSRDLSPISK-GFHTIPSTDISMFTLSRDPSKLTMG------TLLNSDRDHAFLQFHN--------------STPKEFKESLHNNPANRRTTPV----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O60359-1", "uniprot_id": "CCG3_HUMAN", "id": "O60359-1", "name": "Voltage-dependent calcium channel gamma-3 subunit", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MRMCDRGIQMLITTVGAFAAFSLMTIAVGTDYWLYSRGVCRTKSTSDNETSRKNEE-----VMTHSGLWRTCCLEGAFRG---VCKKIDHFPED--ADYEQDTAEYLLRAVRASSVFPILSVTLLFFGGLCVAASEFHRSRHNVILSAGIFFVSAGLSNIIGIIVYISANAGDPGQRDSKKS--------YSYGWSFYFGAFSFIIAEIVGVVAVHIYIEKHQQ-------------------------------------------------------------------------------------------------------------------------LRAKSHSEFLKKSTFARLPPYRYRFRRR-----------------------------------------------------------SSSRSTEPRSRDLSPISK-GFHTIPSTDISMFTLSRDPSKITMG------TLLNSDRDHAFLQFHN--------------STPKEFKESLHNNPANRRTTPV----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "E7EY10-1", "uniprot_id": "E7EY10_DANRE", "id": "E7EY10-1", "name": "Voltage-dependent calcium channel gamma-3 subunit", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MLMCDRGVQMLITTVGAFAAFSLMTIAVGTDYWLYSRGVCRVKSNNENETSRKNEE-----VMTHSGLWRTCCLEGTFRG---VCKKIDHFPED--ADYEQDAAEYLLRAVRASSIFPIMSVGLLFMGGLCVAASEFYRSRHNVILSAGIFFVSAGLSNIIGIIVYISANSGDPGQSDSKKS--------YSYGWSFYFGALSFIMAEMVGVLAVHMFIEKHRK-------------------------------------------------------------------------------------------------------------------------LRAKSRTELIKKSAFSRIPSYRYRFRRR-----------------------------------------------------------SSCRSSEPASRDASPMGKSGYTGPAAADISMYTLSRDPSKAAMG------ALLNSER--EFLQAHN--------------SNAKDFKD-----AANRRTTPV----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q2MGK8-1", "uniprot_id": "Q2MGK8_DROME", "id": "Q2MGK8-1", "name": "", "aln": "MRDYPSVPNVFRVASTHSINSENPYNNIRPANVICNTTERPPIAIHQLTTSASIEHSHPSQQAQHQQQQLLHHQQQHHHQQHSPYATLPRGQRLAPQQHQQAGVINTISGSIPATGFSSLAGSFSDLQLNNIGNHSSNSRSNHNSISNNRRQQQQQQQQQQQRLVPHLSRHQPAIEVQQTQQHQQTQQQHVQRQQQQERLASGGAGATDPQGGISNMTTVNGGYLWLITPVAASISVAIVIAALAGPQWLFTEEKLPNANYNGTANFKALDDGAYITKYTKSSLWILCTTLPGLDADSYNCVKIDYFSNEGYQPDPHDSTAAIPYTVTKSCPIFLAAGVFLVISFIVFLIPTCSHQNNLYYFSAGILFIVSGLVMLIGLIAYISILKAEIGSKLRPRSTLQPALIKVSYGQSFFLFVFGFIVTEFVGVLNIFLFINLQEVSYYSRLPCFSVANIHAKLKEGQHPLSDSYKRYKQPGITTASQEGLSSAGQGQQGHQSHHPTHQPHPTAQPPHGILRSGNSRLHQVYDAGRGHPGMTGQIGHSGQTQTLPGACRKHPNAGSNLNLYLHNDLERRFYFEKPAVSKCNLHSRSFAKSLNELCTDTSVSSTHVPAPLLPSAADPLPAPALFADLPQEFPLTRSVSTATEIYPASSSAPAPPSAQMKRKQQRNMATNTNTKISNNPPSSNSQMADQSRLCGLKRGLRKTKDELFQEFCRRAGMRSKPKNIYYISGGDEAEEEEQEDQAKREEVPDDPHRDDDDDADGDDHGFRQFNRMEEEHLYVVGDHAQLVVPRRTSMCVDSMGQPLRRLNSNLSLHTDLSFPGTGGYPGMRMSLPQPADLGQSRTLPRCFLRQSSDSLASQGYPLGSSQQRFSQLMLNQQQNRFVSSTLTLPQVVAPKSQVQWPTAIPSSPSNYSNGYQQHPQPIYPAPTSGSGAPGTTASVSGPPKFQRGYAFDDQQRRSSFVSDAFDLDEIERERRRSHASLFGMGQVRDPYDLINGTAV", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * : * ***.*.* :.::: *:. **::. . . . . : :: *:*.** * : . * ***:*.:: :*:: : :* *. : : : :*.:. : . . :..: :****:*: :** :**:*.*** .: *. :* *** **:: .:.**::*:***: :.::*: :. *. :.:: :: * : . : .:: * :*. :. * * : . : . . :.** . * :.. . *.. : * : . * .: :: *:*. .* ", "identical_positions": 66, "similar_positions": 116, "identity": "6.6%" }, { "cls_id": "homologset.agr.MGI:1859167", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8VHW9-1", "uniprot_id": "CCG4_RAT", "id": "Q8VHW9-1", "name": "Voltage-dependent calcium channel gamma-4 subunit", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MVRCDRGLQMLLTTAGAFAAFSLMAIAIGTDYWLYSSAHICNGTNLTMDDGPP---PRRARGDLTHSGLWRVCCIEG---IYKGHCFRINHFPEDNDYD--HDSSEYLLRIVRASSVFPILSTILLLLGGLCIGAGRIYSRKNNIVLSAGILFVAAGLSNIIGIIVYISSNTGDPSDKRDEDKKNH-----YNYGWSFYFGALSFIVAETVGVLAVNIYIEKNKELRFKTKREFLKAS------------SSS-PYSRMPSYRYRRRRSRSSSRSTEASPSRDASPVGLKITGAIPMGELS--------MYTLSRE-PLKVT------------TAASYSPDQDAG-FLQMHD---------------------FFQQDLKEGFHVSMLNRRTTPV-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9JJV4-1", "uniprot_id": "CCG4_MOUSE", "id": "Q9JJV4-1", "name": "Voltage-dependent calcium channel gamma-4 subunit", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MVRCDRGLQMLLTTAGAFAAFSLMAIAIGTDYWLYSSAHICNGTNLTMDDGPP---PRRARGDLTHSGLWRVCCIEG---IYRGHCFRINHFPEDNDYD--HDSSEYLLRIVRASSVFPILSTILLLLGGLCIGAGRIYSRKNNIVLSAGILFVAAGLSNIIGIIVYISSNTGDPSDKRDEDKKNH-----YNYGWSFYFGALSFIVAETVGVLAVNIYIEKNKELRFKTKREFLKAS------------SSS-PYARMPSYRYRRRRSRSSSRSTEASPSRDASPVGLKITGAIPMGELS--------MYTLSRE-PLKVT------------TAASYSPDQDAG-FLQMHD---------------------FFQQDLKEGFHVSMLNRRTTPV-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9UBN1-1", "uniprot_id": "CCG4_HUMAN", "id": "Q9UBN1-1", "name": "Voltage-dependent calcium channel gamma-4 subunit", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MVRCDRGLQMLLTTAGAFAAFSLMAIAIGTDYWLYSSAHICNGTNLTMDDGPP---PRRARGDLTHSGLWRVCCIEG---IYKGHCFRINHFPEDNDYD--HDSSEYLLRIVRASSVFPILSTILLLLGGLCIGAGRIYSRKNNIVLSAGILFVAAGLSNIIGIIVYISSNTGDPSDKRDEDKKNH-----YNYGWSFYFGALSFIVAETVGVLAVNIYIEKNKELRFKTKREFLKAS------------SSS-PYARMPSYRYRRRRSRSSSRSTEASPSRDVSPMGLKITGAIPMGELS--------MYTLSRE-PLKVT------------TAASYSPDQEAS-FLQVHD---------------------FFQQDLKEGFHVSMLNRRTTPV-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "E7FGK7-1", "uniprot_id": "E7FGK7_DANRE", "id": "E7FGK7-1", "name": "Voltage-dependent calcium channel gamma-4 subunit", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MAWCERGIQMLLATVGAFVAFSLMSIAIGTDYWLYSRAYICNATNASADETQTQ--PKKVRGDLTHSGLWRICCIEG---LNKGSCYRINHFPDDNDYD--TDSSEYLLRIVRASSVFPLLSTILLLLGGLCVGIGRIYNKRNNILLSAGILFVAAGLSNIIGIIVYISSNAGDPSDKRDEDKKNQ-----YNYGWSFYFGALSFIVAEAVAVLAVNIYIEKNKEVRFKARREFIKST------------SSSSPYSRMPSFRYRRRHSRSSSRSTEAS--REASPVGMKMISSVPVGEIN--------MYTLTRD-PLKSG------------TDSSYSPDHDSG-FLQVHN---------------------CFPKDLNDG-----ANRRTTPV-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0ACD6B7X1-1", "uniprot_id": "A0ACD6B7X1_DANRE", "id": "A0ACD6B7X1-1", "name": "", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MAWCDRRVQTVLTSLGALAAISLMSVAIGTDYWLYSRAHICNTTSNSTDETQNLLLPKKTRGDLTHSGLWKICCIEG---INNGSCYWINHFS-VEDYD--TENSEYILRLVRASSLFPILSTILLLLGGVCVGIGHIYSSRNNITLSAGILFVSAGLSNIIGIIVYISSNAGDPGDKKGEDKKNL-----YSYGWSFYSGVLSFILAETIAVLAVNIYIEKNKEVHFK-HFVFNKTTP----------SPSSSIYTTIPSYHYKQQRSHSCSQSRDPFKNTSSVTHG-VISSSLPLVDIS--------MYALGGEHPLLVG------------GQVSYNTDLEHHNFRKVHN---------------------HIPKDVKDN-----LNRRITPV-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q2MGK8-1", "uniprot_id": "Q2MGK8_DROME", "id": "Q2MGK8-1", "name": "", "aln": "MRDYPSVPNVFRVASTHSINSENPYNNIRPANVICNTTERPPIAIHQLTTSASIEHSHPSQQAQHQQQQLLHHQQQHHHQQHSPYATLPRGQRLAPQQHQQAGVINTISGSIPATGFSSLAGSFSDLQLNNIGNHSSNSRSNHNSISNNRRQQQQQQQQQQQRLVPHLSRHQPAIEVQQTQQHQQTQQQHVQRQQQQERLASGGAGATDPQGGISNMTTVNGGYLWLITPVAASISVAIVIAALAGPQWLFTEEKLPNANYNGTANFKALD-DGAYITKYTKSSLWILCTTLPGLDADSYNCVKIDYFSNEGYQPDPHDSTAAIPYTVTKSCPIFLAAGVFLVISFIVFLIPTCSHQNNLYYFSAGILFIVSGLVMLIGLIAYISILKAEIGSKLRPRSTLQPALIKVSYGQSFFLFVFGFIVTEFVGVLNIFLFINLQEVSYYSRLPCFSVANIHAKLKEGQHPLSDSYKRYKQPGITTASQEGLSSAGQGQQGHQSHHPTHQPHPTAQPPHGILRSGNSRLHQVYDAGRGHPGMTGQIGHSGQTQTLPGACRKHPNAGSNLNLYLHNDLERRFYFEKPAVSKCNLHSRSFAKSLNELCTDTSVSSTHVPAPLLPSAADPLPAPALFADLPQEFPLTRSVSTATEIYPASSSAPAPPSAQMKRKQQRNMATNTNTKISNNPPSSNSQMADQSRLCGLKRGLRKTKDELFQEFCRRAGMRSKPKNIYYISGGDEAEEEEQEDQAKREEVPDDPHRDDDDDADGDDHGFRQFNRMEEEHLYVVGDHAQLVVPRRTSMCVDSMGQPLRRLNSNLSLHTDLSFPGTGGYPGMRMSLPQPADLGQSRTLPRCFLRQSSDSLASQGYPLGSSQQRFSQLMLNQQQNRFVSSTLTLPQVVAPKSQVQWPTAIPSSPSNYSNGYQQHPQPIYPAPTSGSGAPGTTASVSGPPKFQRGYAFDDQQRRSSFVSDAFDLDEIERERRRSHASLFGMGQVRDPYDLINGTAV", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *. : :::. .* :.::: *:. **:: : * . : . *:*.** :* * *::*. :.: : * *. : : : ::*::. : . .* :******: :** :**:*.*** .: ..* .. .** **: .:.**::* :.** : ::*: :: :. * :. ..* *. :.. *.: . : . . * : :* * .: :*: : :.::: . .*. ", "identical_positions": 52, "similar_positions": 100, "identity": "5.19%" }, { "cls_id": "homologset.agr.MGI:1859168", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8VHW3-1", "uniprot_id": "CCG6_MOUSE", "id": "Q8VHW3-1", "name": "Voltage-dependent calcium channel gamma-6 subunit", "aln": "MMWSNFFMQEEDRRRT---AVG------RRRAQEQQNLGLTPEREGKIKLGLLVAIVGATLAVLAVGTEFWVELNTYKTN-GSAVCEAAHLGLWKVCIKRLWQADVPAGRETCGPAELPGEANCTYFKFFTTGENARIFQRTTKKEVNLAAAVIAVLGLTAMALGCLCVIMVLSKGAESLLRLGAVCFGLSGLLLFVSLEVFRHSVGALLQGVNPETPPAPRLAYEYSWSLGCGVGAGLILLLGGVCFLLLTLPSWPWRSLCPKWGGPTA", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8VHW7-1", "uniprot_id": "CCG6_RAT", "id": "Q8VHW7-1", "name": "Voltage-dependent calcium channel gamma-6 subunit", "aln": "MMWSNFFMQEEDRRRT---AVG------RRRAQEQQNLGLTPEREGKIKLGLLVAIVGATLAVLAVGTEFWVELNTYKTN-GSAVCEAAHLGLWKVCIKRLWQADVPAGRETCGPAELPGEANCTYFKFFTTGENAHIFQRTTKKEVNLAAAVIAVLGLTAMALGCLCVIMVLSKGAEFLLRLGAVCFGLSGLLLFVSLEVFRHSVRALLQGVNPETPPAPRLAYEYSWSLGCGVGAGLILLLGGVCFLLLTLPSWPWRSLCPKRGGPTA", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9BXT2-1", "uniprot_id": "CCG6_HUMAN", "id": "Q9BXT2-1", "name": "Voltage-dependent calcium channel gamma-6 subunit", "aln": "MMWSNFFLQEENRRRG---AAG------RRRAHGQGRSGLTPEREGKVKLALLLAAVGATLAVLSVGTEFWVELNTYKAN-GSAVCEAAHLGLWKACTKRLWQADVPVDRDTCGPAELPGEANCTYFKFFTTGENARIFQRTTKKEVNLAAAVIAVLGLAVMALGCLCIIMVLSKGAEFLLRVGAVCFGLSGLLLLVSLEVFRHSVRALLQRVSPEPPPAPRLTYEYSWSLGCGVGAGLILLLGAGCFLLLTLPSWPWGSLCPKRGHRAT", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "E7F9M5-1", "uniprot_id": "E7F9M5_DANRE", "id": "E7F9M5-1", "name": "", "aln": "-MWSNFFLQQDDDGRGGMGALGGAGSKSGRTGKRARPPRMSDSEEGKIKLAFFLVLIGVTLTVLGMGTEFWVELSQPKHFRNNQTCEMAHYGLWKSCVRTLWVTDIDPERESCGPAELPGESNCTYFKFYTSGENAVIFKKTTQKSLHIAGAMLALLSLFMMVMGSVCITMSISKSVPFFLKPATICFVCSGILVLLSIIVFHQSILALLASDHSIP-----LHHELSWSVACVGSSGAILIIGGLIFLLLSLPYNPLEKCFRQQSSSDA", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ******:*::: * * * * .: :: ..***:**.:::. :*.**:**.:********. * .. .** ** **** * : ** :*: *::*********:*******:*:**** **::**:*.:::*.*::*:*.* *.:*.:*: * :**.. :*: .::** **:*:::*: **::*: *** . . * :* ***:.* .:* **::*. ****:** * . : . :", "identical_positions": 110, "similar_positions": 81, "identity": "40.74%" }, { "cls_id": "homologset.agr.MGI:1859169", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P40807-1", "uniprot_id": "DCOR1_DROME", "id": "P40807-1", "name": "Ornithine decarboxylase 1", "aln": "---------------------MAAATPEIQFYERELNIR----RVIEECDLQRL-----------------------------DQALNICDLSSVERKLRLWQKLLPRIKPFYAVKCNDDPMVVRLLAQLGAGFDCASKNEVKLVLGFDVSPERIIFANPCRPVSHLEYAKEHQVSNGTVDNEFEVYKLHTHYPNSNLIVRFKSEAKEAQCPLGDKFGCDADVDAAALMLLAKSLELKVTGTSFHVGSGCSELQAYDRAIKKAKNLFKFGALLG--YDMDFLDIGGGFPGSDDVKFEKIAESVNTSVQRHFPDER-VHIIAEPGRFFVAAACTLVCKIHAKREIRNEAGKLDT----------VMYYLNDGVYGSFNCILYDHQVVIA-------EHYLDNAESLP-------------HLKSLIWGPSCDALDKISEDLHLPN-LNRGDLLGFRNMGAYTMPIASAFNGFEVPKTLYFQAI----------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P40808-1", "uniprot_id": "DCOR2_DROME", "id": "P40808-1", "name": "Ornithine decarboxylase 2", "aln": "---------------------MVNGDLRIQYYDEELNIR----KVIEQADLEHL-----------------------------DQALNICDLSSLERKLRLWHKLMPRIEPHYAVKCNDDPVVVKFLADLGTGFDCASKNELKLVLGLGVSPERIIFAHPCRPASHLRYAKEQQVVNGTVDNEYEIYKLRKHYPDSNLIVRFKSEAKKALCPLGDKYGCDAEADAAALMLLAKALGLKVTGTSFHVGSGCSEVEAYDRAIEKAENIFKVGEMIG--HKMELLDVGGGFPGIDDEMFEEIAQSVNTSVELRFPDKR-IRIISEPGRFFVEAAYTLICKVHAKREVRSKDGKLDT----------MMYYLNDGIFGAFAGMFYYPEEVAP-------ELYLDEAESLP-------------KLKSVIWGPSCDAMDKIS-DLLLPN-LNPGDLLGFRNMGAYTMPIASPFNGFDVPETRFFKAK----------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P08432-1", "uniprot_id": "DCOR_YEAST", "id": "P08432-1", "name": "Ornithine decarboxylase", "aln": "MSSTQVGNALSSSTTTLVDLSNSTVTQKKQYYKDGETLHNLLLELKNNQDLELLPHEQAHPKIFQALKARIGRINNETCDPGEENSFFICDLGEVKRLFNNWVKELPRIKPFYAVKCNPDTKVLSLLAELGVNFDCASKVEIDRVLSMNISPDRIVYANPCKVASFIRYAASKNVMKSTFDNVEELHKIKKFHPESQLLLRIATDDSTAQCRLSTKYGCEMEN-VDVLLKAIKELGLNLAGVSFHVGSGASDFTSLYKAVRDARTVFDKAANEYGLPPLKILDVGGGFQ---FESFKESTAVLRLALEEFFPVGCGVDIIAEPGRYFVATAFTLASHVIAKRKLSENE---------------AMIYTNDGVYGNMNCILFDHQEPHPRTLYHNLEFHYDDFESTTAVLDSINKTRSEYPYKVSIWGPTCDGLDCIAKEYYMKHDVIVGDWFYFPALGAYTSSAATQFNGFEQTADIVYIDSELD-------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "O14977-1", "uniprot_id": "AZIN1_HUMAN", "id": "O14977-1", "name": "Antizyme inhibitor 1", "aln": "---------------------MKGFIDDANYSVGLLDEGTNLGNVIDNYVYEHT--------------------------LTGKNAFFVGDLGKIVKKHSQWQNVVAQIKPFYTVKCNSAPAVLEILAALGTGFACSSKNEMALVQELGVPPENIIYISPCKQVSQIKYAAKVGVNILTCDNEIELKKIARNHPNAKVLLHIATEDNIGGEEGNMKFGTTLKNCRHLLECAK-ELDVQIIGVKFHVSSACKESQVYVHALSDARCVFDMAGEIG--FTMNMLDIGGGFTG-TEFQLEEVNHVISPLLDIYFPEGSGVKIISEPGSYYVSSAFTLAVNIIAKKVVENDKFPSGVEKTGS-DEPAFMYYMNDGVYGSFASK-LSEDLNTIP------EVHKK-YKEDEP------------LFTSSLWGPSCDELDQIVESCLLPE-LNVGDWLIFDNMGADSFHEPSAFNDFQRPAIYYMMSFSDWYEMQDAGITSDSMMKNFFFVPSCIQLSQE-DSFSAEA", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q63764-1", "uniprot_id": "AZIN1_RAT", "id": "Q63764-1", "name": "Antizyme inhibitor 1", "aln": "---------------------MKGFIDDANYSVGLLDEGTNLGNVIDNYVYEHT--------------------------LTGKNAFFVGDLGKIVKKHSQWQNVVAQIKPFYMVKCNSTPAVLEILAALGTGFACSTKNEMALVQELGVSPENIIYTSPCKQASQIKYAAKVGVNIMTCDNEVELKKIARNHPNAKVLLHIATEDNIGGEDGNMKFGTTLKNCRHLLECAK-ELDVQIIGVKFHISSACKEYQVYVHALSDARCVFDMAGEFG--FTMNMLDIGGGFTG-TEIQLEEVNHVISPLLDIYFPEGSGIQIISEPGSYYVSSAFTLAVNIIAKKVVENDKLSSGVEKNGS-DEPAFVYYMNDGVYGSFASK-LSEDLNTVP------EVHKK-YKEDEP------------LFTSSLWGPSCDELDQIVESCLLPE-LSVGDWLIFDNMGADSLHGPSAFSDTQRPAIYFMMSLSDWYEMQDAGITSDAMMKNFFFAPSCIQLSQE-DNFSTEA", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0A8M1N598-1", "uniprot_id": "A0A8M1N598_DANRE", "id": "A0A8M1N598-1", "name": "", "aln": "-------------------MSMKGSLDELHYSVELLEGSAALRDVIDKHIYDQT--------------------------FAQKSAFFAADLGVIVQQQARWRNKMDQIRPFYTVKSNSSPVVVELLASLGTGFICSNKHELDLVKGFGVSSQDIILGGTCKQLSHIKYAAKHNIPLLVCDNEAEMRKIARCHPKAKVLLLLTSESCCEKEEMAIPFGSTLKDCRRLLECAAGELNLQVTGVKFNIPSCCQEVEKFSRAVSEARCVFDMGEELG--FEMNILDIGGGFDG-SEEQLDKVNQMLKPMLDMYFPRSTGLSIIAEPGAYYVSSAFTLAVNIIDKKTVARDCSAQPHDALSANDEPEFLYHINDGVYGSFASKLLCEDSIATP------LAHKH-VSADEP------------LFSSSLWGPSEDDLDLVMERCLLPE-LSVGDWLLFRNAGASALGSAFSHGDQHKPPVFYSITEYDWQEIHNSGVTVDVRMKNFSLVPCCLQPNMSGASISTPA", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q801V3-1", "uniprot_id": "Q801V3_DANRE", "id": "Q801V3-1", "name": "", "aln": "---------------------MKGFVDAPNYFIELLEGGTTLENVIDNHIYEQN--------------------------LAEKNAFVVADLGALMRQHVVWKTTMPLVRPFYPVSCNSSPVVIELLSALGVGFVCANKAETTLVLSHDVPPENIILSGVCKQLSLIKHAAKTGINFLLCENEAELRKIARAHPEAKLLLQVSTEAQI--EEASVTIGCSLKGCRHLLELAK-ELNVSVAGVTFQVPASCKDPQAYTHALSDARCIFDMGKELG--FDMNILDIGGGFSG-SEFQLKQVHSVIRPLLEAYFPSESGVSIIAEPGNFFVFSCFTLAVNVIGKKAAYRNLHTSTHDKLTSSDAPEFVYYMNDGVYGSFMGR-LFGNIISTP------SVHKMSLTLDEP------------VFSSSLWGPSCDPLDQVVERCLLPE-LAVGDWLVFSNMGASGQEGPATFSDTDQPPVYYTISTDDWFEMQEAGISLDDTMKNLSLVQFGL-------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0ABJ3HKJ7-1", "uniprot_id": "A0ABJ3HKJ7_MOUSE", "id": "A0ABJ3HKJ7-1", "name": "", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MPPKKRRRF-----TRLFG-P----------LSHGELSDR----------------------VYNYPEG-LGEVLYR------------------EQFDFNAEPP------------------WEPS---------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : * ::. * * .: : :* * . * *: ", "identical_positions": 7, "similar_positions": 10, "identity": "1.34%" }, { "cls_id": "homologset.agr.MGI:1859170", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9WTY1-1", "uniprot_id": "PDCD7_MOUSE", "id": "Q9WTY1-1", "name": "Programmed cell death protein 7", "aln": "MALPPFFAQSRQGPPPPQPPPSAPFGCPPPPLPSPAFPPPLPQRPGPFPGASAPFLQPPLALQPRAPAEASRGGGG---GGAFFPVPPPPLPPPPPQCRPFPGPDAVERPRPPPPGPGPPWSPRWAEAPPPP-DVLGDAALQRLRDRQWLEAVFGNPRRPGGLRTPRTPAGPSLGEVRARLRSALRLVRRLRSLGQSLREAEADGAAWASLHAQAAPLRAELAERLQPLRQAAYVGEARRRLERVRRR-VRVRERARDRRLS-GRRGAQRTEREQEIDRWRVKCVQEVEEKKRDEELKAAADGVLAEVRKKQSDTKRMVDILRALEKLRKLRKEAAARKGVCPPASADETFEHHLQRLRKLIKKRSELYEAEERALRVMLEGEQEEERRRELEKKQRKEKEKLLLQKREIESKLFGDPDEFPLAHLLQPFRQYYLQAEHSLPALIQIRHDWDQYLVPSDHPKGNSVPQGWVLPPLPSNDIWATAIQLH", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D4ACM6-1", "uniprot_id": "D4ACM6_RAT", "id": "D4ACM6-1", "name": "", "aln": "MALPPFFAQSRQGPPPPQPPPSAPFSCPPPPLPSPVFPPPLPQRPGPFPGASAPFLQPPIALQPRASAEASRGGGGSGGGGAFFPVPPPPLPPPP-QCRPFPGPDVVERPRPPPPGPGPPWSPRWAEAPPPP-DVLGDAALQRLRDRQWLEAVFGNPRRPVGPRTPRTPAGPSLGEVRARLRAALRLVRRLRSLGQSLREAEADGAAWVSLHAQAAPLRAELAERLQPLAQAAYMGEARRRLERVRRRRLRLRERARERETEREAEAAQATEREQEIDRWRMKCVQEVEEKKREQELKAAADGVLAEVRKKQSDTKRMVDILRALEKLRKLRKEAAARKGVCPPAAADETFEHHLQRLRKLIKKRSELYEAEERALRVMLEGEQEEERRRELEKKQRKEKEKLLLQKREIESKLFGDPDEFPLAHLLEPFRQYYLQAEHSLPALIQIRHDWDQYLVPSDHPKGNSIPQGWVLPPLPSNDIWATAVQLH", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8N8D1-1", "uniprot_id": "PDCD7_HUMAN", "id": "Q8N8D1-1", "name": "Programmed cell death protein 7", "aln": "MALPPFFGQGRPGPPPPQPPPPAPFGCPPPPLPSPAFPPPLPQRPGPFPGASAPFLQPPLALQPRASAEASRGGGG---AGAFYPVPPPPLPPPPPQCRPFPGTDAGERPRPPPPGPGPPWSPRWPEAPPPPADVLGDAALQRLRDRQWLEAVFGTPRRAGCPVPQRTHAGPSLGEVRARLLRALRLVRRLRGLSQALREAEADGAAWVLLYSQTAPLRAELAERLQPLTQAAYVGEARRRLERVRRRRLRLRERAREREAEREAEAARAVEREQEIDRWRVKCVQEVEEKKREQELKAAADGVLSEVRKKQADTKRMVDILRALEKLRKLRKEAAARKGVCPPASADETFTHHLQRLRKLIKKRSELYEAEERALRVMLEGEQEEERKRELEKKQRKEKEKILLQKREIESKLFGDPDEFPLAHLLEPFRQYYLQAEHSLPALIQIRHDWDQYLVPSDHPKGNFVPQGWVLPPLPSNDIWATAVKLH", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*******.*.* *********.***.*********.***********************:******.********* .***:*********** *******.*. ******************.****** **********************.***. . ** ************ *********.*.*:***********. *::*:************** ****:************* :*:*****:*. . ..*: .**********:***********::**********:******:********************************:***** ************************************:*************:************************:************************************ :******************::**", "identical_positions": 419, "similar_positions": 44, "identity": "85.86%" }, { "cls_id": "homologset.agr.MGI:1859179", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "F7EXX5-1", "uniprot_id": "F7EXX5_RAT", "id": "F7EXX5-1", "name": "Interferon regulatory factor 3", "aln": "MLHTKTLSQNIHKNNVEKTKQKKRQQLGEDSGNELRNCTVCAGWIMGTPKPLILPWLVSQLDLGQLKGVAWLDESRTKFRIPWKHGLRQDAQMADFGIFQAWAEASGAYTPGKDKPDLSTWKRNFRSALNRKEVLRLAEDRSKDPFDPHKVYEFVTPGG---------------------------------ARDFVHLDTSPDTNGKSSLSDHQEDLL-ELLDHMALGPLPDEGSSDLPIAS-----DPS-QPPLSPIVNN---FPNPAPQENPLRQLLA----EEQWEFEVTAFYRGRQVFQQTLFCPGGLRLVGS----TSDNGTLPWQPVTLPDPEEFLTDRLVREYVRQVLKGLGKGLVLWRAGQCLWAQRLGHSHSFWALGEELLPDSGRGPDGEVPKDKNGVVFDLRPFVADLIAFMEGSRHSPRYTLWFCVGESWPQD--QPWVKRLVMVKVVPTCLKELLEMAREGGASSLK-TVDLHISNSQPISLTSDQYKACLQDLVEDMDFQATGET", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P70671-1", "uniprot_id": "IRF3_MOUSE", "id": "P70671-1", "name": "Interferon regulatory factor 3", "aln": "---------------------------------------------METPKPRILPWLVSQLDLGQLEGVAWLDESRTRFRIPWKHGLRQDAQMADFGIFQAWAEASGAYTPGKDKPDVSTWKRNFRSALNRKEVLRLAADNSKDPYDPHKVYEFVTPG----------------------------------ARDFVHLGASPDTNGKSSLPHSQENLP-KLFDGLILGPLKDEGSSDLAIVS-----DPS-QQLPSPNVNN---FLNPAPQENPLKQLLA----EEQWEFEVTAFYRGRQVFQQTLFCPGGLRLVGS----TAD-MTLPWQPVTLPDPEGFLTDKLVKEYVGQVLKGLGNGLALWQAGQCLWAQRLGHSHAFWALGEELLPDSGRGPDGEVHKDKDGAVFDLRPFVADLIAFMEGSGHSPRYTLWFCMGEMWPQD--QPWVKRLVMVKVVPTCLKELLEMAREGGASSLK-TVDLHISNSQPISLTSDQYKAYLQDLVEDMDFQATGNI", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q14653-1", "uniprot_id": "IRF3_HUMAN", "id": "Q14653-1", "name": "Interferon regulatory factor 3", "aln": "---------------------------------------------MGTPKPRILPWLVSQLDLGQLEGVAWVNKSRTRFRIPWKHGLRQDAQQEDFGIFQAWAEATGAYVPGRDKPDLPTWKRNFRSALNRKEGLRLAEDRSKDPHDPHKIYEFVNSG----------------------------------VGDFSQPDTSPDTNGGGSTSDTQEDILDELLGNMVLAPLPDPGPPSLAVAP-----EPCPQPLRSPSLDNPTPFPNLGPSENPLKRLLVP---GEEWEFEVTAFYRGRQVFQQTISCPEGLRLVGS----EVGDRTLPGWPVTLPDPGMSLTDRGVMSYVRHVLSCLGGGLALWRAGQWLWAQRLGHCHTYWAVSEELLPNSGHGPDGEVPKDKEGGVFDLGPFIVDLITFTEGSGRSPRYALWFCVGESWPQD--QPWTKRLVMVKVVPTCLRALVEMARVGGASSLENTVDLHISNSHPLSLTSDQYKAYLQDLVEGMDFQGPGES", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M6Z9B8-1", "uniprot_id": "A0A8M6Z9B8_DANRE", "id": "A0A8M6Z9B8-1", "name": "", "aln": "---------------------------------------------MTQAKPLFVPWLYEQIQSGRYPGVCWKNEDCTQFSIPWKHALRQDSNSDDVLIFKAWAQTSAAGD-GRLNGDPSVWKRNFRSALRAKG-FKMISDKKNDGADPHKVYQFPSDPHSAASGSEGSQETDISPHLYVDNVFTASFDLDQHLTGLHLQDPSARVHIILNPNDLYVDPGTQIYDFQAVVPIEAISSSDEGAVGGLGQISPTEGAMAVNHISREYQQTATQPHLGAVPDHTAIPEPNLATFFRIKVYYKGKMVMEQLVENDSGFRLMYHRNMDESGLQDGAGLPVVTLPPAEGMPDQMQTRLTNDILDNLG-GLEIRRSDGVIHGHRWGSSRIYWGLCKHERSQTPR----ELSKNTPQPIYLMKDYISGLMQFIQTGGESPSCTLYFFLGEKWPDPKMKPWEKKLIMIEVNLTALEFLKSMAVEQGASSLQ----------------SDELQLSLEQMMELC--------", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * .** ::*** .*:: *: **.* ::. *:* *****.****:: *. **:***:::.* *: : * ..*********. * ::: *..:* ****:*:* . .: ..*. .: . . : :: . : *: .... . .* :.. * ..: . *.:..:*:*: *::* : *:**: . . **. * :.*: . .:*. ** ** : ::. : .:* * .: :*.: :. .:: : *: *:. :: : :: .*: * : . .** :*:* :** **: :** *:*:*::* *.*. * .** *****: **: : *::::* ", "identical_positions": 105, "similar_positions": 135, "identity": "20.19%" }, { "cls_id": "homologset.agr.MGI:1859181", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9NQE7-1", "uniprot_id": "TSSP_HUMAN", "id": "Q9NQE7-1", "name": "Thymus-specific serine protease", "aln": "MAVWLAQWLGPLLLVSLWGLLAPAS-LLRRLGEHIQQFQESSAQGLGLSLGPGAAALPKVGWLEQLLDPFNVSDRRSFLQRYWVN-DQHWVGQDGPIFLHLGGEGSLGPGSVMRGHPAALAPAWGALVISLEHRFYGLSIPAGGLEMAQLRFLSSRLALADVVSARLALSRLFNISSSSPWICFGGSYAGSLAAWARLKFPHLIFASVASSAPVRAVLDFSEYNDVVSRSLMSTAIGGSLECRAAVSVAFAEVERRLRSGGAAQAALRTELSACGPLGRAENQAELLGALQALVG---GVVQYDGQTG--APLSVRQLCGLLLGGGGNRSHSTPYCGLRRAVQIVLHSLGQKCLSFSRAETVAQLR-STEPQLSGVGDRQWLYQTCTEFGFYVTCENPRCPFSQLPALPSQLDLCEQVFG--LSALSVAQAVAQTNSYYGGQTPGANKVLFVNGDTDPWHVLSVTQALGSSESTLLIRTGSHCLDMAPERPSDSPSLRLGRQNIFQQLQTWLKLAKESQIKGEV", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9QXE5-1", "uniprot_id": "TSSP_MOUSE", "id": "Q9QXE5-1", "name": "Thymus-specific serine protease", "aln": "MAVK-APWLGFLLLVSLWGLSTPAL-LLRRLREHIQKFQESSSLHPGFGLGHGPGAVPKQGWLEQPLDPFNASDRRTFLQRYWVN-DQHRTGQDVPVFLHIGGEGSLGPGSVMAGHPAALAPAWGALVISLEHRFYGLSMPAGGLDLALLRYLSSRHALADVASARQALSGLLNVSSSSPWICFGGSYAGSLATWARLKFPHLVFAAVASSAPLSAVVDFSAYNQVVARSLTQVAIGGSLECLAAASTAFTEVERLLRAGPAAQAVLREELGACGSLDLTEDQAELLGALQALVG---GTVQYDGQAG--APLSVRQLCGLLLGKWGNRSRSTPYLGLRRAVQIVLRSMGQKCLSFSRAETVAQLS-NTEPQVSGVGDRQWLYQTCTEFGFYVTCEGLQCPFSQLPALPFQLELCEQVFG--LSPASVAQAVAQTNSYYGGQSPGATQVLFVNGDTDPWHVLSVTQDLGLSEPALLIPSASHCFDMAPMRPSDSPSLRLGRQKISQQLQDWLKDIKKSQS----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9VS02-1", "uniprot_id": "Q9VS02_DROME", "id": "Q9VS02-1", "name": "Serine protease K12H4.7", "aln": "MLFIGGVLRPLGVGLLLLGLLAPISGMGFRRGRLTKGFLGEPSKIPTLQR----SLHSEDLWFEQRLDHFKSSDKRTWQQRYFVNADFYRNDSSAPVFLMIGGEGEASAKWMREGAWVHYAEHFGALCLQLEHRFYGKSHPTADLSTENLHYLSSEQALEDLASFVTAMKVKFNLGDGQKWIAFGGSYPGSLAAWAREKYPELIYGSISSSGPLLAEVDFKEYFEVVKASLAAYKP----ECVDAVTRSFAQVEILLKHMIGQRSLDEKFKTCTPIKDSIENDLDMANFFENLAGNFAGVVQYNKDNSPHATITIDDICDVMLN----TTAGPPVTRLGLVNDMLLKESNTTCLDYKYDKMVADMKNVSWDSETAKGMRQWTYQTCHEFGFYQTSDNPADTFGDRFGVDFFIRQCMDVFSKNMNAKFLKLVVSATNDNYGALKPKTTNVLYVHGSIDPWHALGLVKSTNAALPTIYIEGTAHCANMYEPVKTDPPQLVAARNKILKFLAKLLDGYTSALI----", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* . . : : * ** :* : * . : * ..: : . .: *:** ** *: **:*:: ***:** * : ... *:** :****. .. : * . * :*** :.******* * *:..*. *::***. ** *:.* *:. :*:.... **.*****.****:*** *:*.*::.:::**.*: * :**. * :** ** ** *.: :*::** *: . :: . . . *:: :: . :: *.* *.***: : . *.::: ::*.::*. : ..* * . :::*:. . .**.:. : **:: : . :. * *** **** ***** *.:. .*.: .: : * :**. :.. : .*: **. **. .* :.:**:*:*. ****.*.:.: . : .:: * :** :* :*.*.* .*::* : * *. ..: ", "identical_positions": 150, "similar_positions": 172, "identity": "28.63%" }, { "cls_id": "homologset.agr.MGI:1859183", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "B4F769-1", "uniprot_id": "SMAL1_RAT", "id": "B4F769-1", "name": "SNF2 related chromatin remodeling annealing helicase 1", "aln": "MSLPLTEEQRKKIEENRQKALARRAEKLWAEQPQSTASGSSAAR-PSQCKQNSLLNLPAEPSKPEGHATISKGQNLNNSLPAAQRPHSSPCFQPSTAEEAKGLWKSEGKMSAACP-----------------NPSPPEVSNQQLLGSKSSEGHPQAT----------------------QDTAASCPRPFPRDPKLEAKAGRPSTSGQSISDTFYALGEKTPKTDGRPAKALQTSPQK-ASCLRGMCLRTGD-RFRVKIGYNKELIEVFKSLPSRRYDSFTKTWDFSMSDYRALMKAVERLSTVSLQPLEEVDG--------TGGQTSLPSAPS---------LTFVTGRCMLISRARFEVDIG-YSEVVIALFKQMESRNYDPKTRKWNFLLEEHNKLIARSRELK-QVQLDPLPKTLTLAFASQLEKTSLQSKADVPEADLSGVDAKLVSNLMPFQREGVSFAISKRGRLLLADDMGLGKTIQAICIAAFYRKEWPLLVVVPSSVRFTWEQAFLRWLPSLSPEDINVVVTGKGRLTAGLVNIVSFDLLSKLEKQLKT-PFKVVIIDESHFLKNIKTARCRAAVPILKVAKRVILLSGTPAMSRPAELYTQIIAVKPTFFPQFHAFGLRYCDAKRLPWGWDYSGSSNLGELKLLLEEAVMLRRLKSDVLSQLPAKQRKMVVVNPGRISTRAKAALDAAAKEMT-KDKTKQQQKEALLVFFNRTAEAKIPCVIEYILDLLESGREKFLVFAHHKVLLDAIAKELERKNVQHIRIDGSTPSADREDLCQQFQLSKGHTVAVLSITAANMGLTFSSADLVVFAELFWNPGVLIQAEDRVHRIGQTNSVGIHYLVAKGTADDYLWPLIQEKIKVLGEAGLSETNFSEMTEATDYLYKDPKQKTIYSLFQQSFEDDGNDMEFLEAAESFELGSTSGTSGNSSQELGDITDENALADSPPKKRRFEFFDNWDSFTSPF", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8BJL0-1", "uniprot_id": "SMAL1_MOUSE", "id": "Q8BJL0-1", "name": "SNF2 related chromatin remodeling annealing helicase 1", "aln": "MSLPLTEEQRKKIEENRQKALARRAEKLS-EQPQSAASGSSAAG-PSQSKQGSLLNLLAEPSKPVGHASIFKQQNLSNSFPTDQRPHSSRCSQPSPAEETTGLWKTQGEMSTACPKP---------------NPSPPGASNQPLLGYKSSEGQPQAT----------------------WDTGASSSGPFPRDPELEAKAARPSTSRQSISDSFYVLGGKTPRTEGRPPNILQTTPQN-TGFLRGACIKTGD-RFRVKIGYNQELIAVFKSLPSRHYDSFTKTWDFSMSDYRALMKAVERLSTVSLKPLDEAGGS-------VGGQTSLPSAPS---------LTFVTGKCMLISRVRFEVDIG-YSEAVIGLFKQMESRSYDIKTRKWSFLLEEHNKLIARSRELK-QVQLDPLPKTVTLAFASQLEKTSPKLKADVPEADLSGVDAKLVSSLMPFQREGVSFAISKRGRLLLADDMGLGKTVQAICIAAFYRKEWPLLVVVPSSVRFTWEQAFLRWLPSLSPENINVVVTGKGRLTAGLVNIVSFDLLCKLERQLKT-PFKVVIIDESHFLKNIKTARCRAAVPILKVAKRVILLSGTPAMSRPAELYTQIIAVKPTFFPQFHAFGLRYCDAKRLPWGWDYSGSSNLGELKLLLEEAIMLRRLKSDVLSQLPAKQRKMVVVNPGRISSRAKAALDAAAKEMT-KDKTKQQQKEALLVFFNRTAEAKIPCVVEYILDLLDSGREKFLVFAHHKVILDAVAKELERKNVQHIRIDGSTPSADREAQCQRFQLSKGHTVALLSITAANMGLTFSTADLVVFAELFWNPGVLIQAEDRVHRIGQTNSVSIHYLVAKGTADDYLWPLIQEKIKVLGEAGLSETNFSEMTEATDYVHKDPKQKTIYDLFQQSFEDDGNDMEFLEAAESFELGSTSGTSGNISQDLGDLLDED--EGSPPKKSRFEFFDNWDSFSSPF", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9NZC9-1", "uniprot_id": "SMAL1_HUMAN", "id": "Q9NZC9-1", "name": "SNF2 related chromatin remodeling annealing helicase 1", "aln": "MSLPLTEEQRKKIEENRQKALARRAEKLLAEQHQRTSSGTSIAGNPFQAKQGPSQNFPRESCKPVSHGVIFKQQNLSSSSNADQRPHDSHSFQ------AKGIWKKPEEMPTACPGHSPRSQMALTGISPPLAQSPPEVPKQQLLSYELGQGHAQASPEIRFTPFANPTHKPLAKPKSSQETPAHSSGQPPRDAKLEAKTAKASPSGQNISYIHSSSESVTPRTEGRLQQKSGSSVQKGVNSQKGKCVRNGD-RFQVLIGYNAELIAVFKTLPSKNYDPDTKTWNFSMNDYSALMKAAQSLPTVNLQPLEWAYGSSESPSTSSEGQAGLPSAPS---------LSFVKGRCMLISRAYFEADIS-YSQDLIALFKQMDSRRYDVKTRKWSFLLEEHSKLIAKVRCLP-QVQLDPLPTTLTLAFASQLKKTSLSLTPDVPEADLSEVDPKLVSNLMPFQRAGVNFAIAKGGRLLLADDMGLGKTIQAICIAAFYRKEWPLLVVVPSSVRFTWEQAFLRWLPSLSPDCINVVVTGKDRLTAGLINIVSFDLLSKLEKQLKT-PFKVVIIDESHFLKNSRTARCRAAMPVLKVAKRVILLSGTPAMSRPAELYTQIIAVKPTFFPQFHAFGLRYCDAKRMPWGWDYSGSSNLGELKLLLEEAVMLRRLKSDVLSQLPAKQRKIVVIAPGRINARTRAALDAAAKEMTTKDKTKQQQKDALILFFNRTAEAKIPSVIEYILDLLESGREKFLVFAHHKVVLDAITQELERKHVQHIRIDGSTSSAEREDLCQQFQLSERHAVAVLSITAANMGLTFSSADLVVFAELFWNPGVLIQAEDRVHRIGQTSSVGIHYLVAKGTADDYLWPLIQEKIKVLAEAGLSETNFSEMTESTDYLYKDPKQQKIYDLFQKSFEKEGSDMELLEAAESFDPGSASGTSGSSSQNMGDTLDESSLTASPQKKRRFEFFDNWDSFTSPL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "B2ZFP3-1", "uniprot_id": "SMAL1_DANRE", "id": "B2ZFP3-1", "name": "SNF2 related chromatin remodeling annealing helicase 1", "aln": "MSVSLTPEQQRRIEENRKKALARRAERQA----QIADPG------PAQNKHTQS-GTTGGPAKNNQHFASDRGQ---SGAPTRQT--------------------QLIDINAACT-----------------KTAPPTS-----------------------------------------ITAASTASSFYG------QAGKPSTG-----------EKRPPKP---PEPAANIPAKKPAVYLRGRCVSHSENRFRVEVGYHADLILVFKSIPSKNYDPATKMWNFSLEDYQMLMEQVAHLPSISLKPLEGMEGLNISASTCRPKDAAAMAALMRLCQGWQKPGATIKGKCVLVSRSRLEVDIG-YQADVIGIFKQMPSKSYDMKTRKWTFLLEDYGKLMADLNELP-TVETEPLPHAVLQSFSSQFEKT-QSQAPVPPEADLSHIDPQLTRSLMPFQRDGVNFAVSREGRLLLADDMGLGKTVQAICIAAYYRSEWPLLVVAPSSVRFTWAEAFRRWLPSVKPDSINVVVKGKDSLRSGLINIISYDLLNKMDKQPPSSPFNVIIMDESHFLKNMKTARCRAALPLLKTAKRVILLSGTPAMSRPAELYTQIQAVRPALFPRFHDFGTRYCDAKQLPWGWDYSSSSNLTELKLLLEESLMLRRLKSEVLSQLPAKQRKVVTVTTDGINSRTKAALNAAARELAKGYHNKSQEKEALLVFFNHTAEAKIRAIMEYISDMLECGREKFLVFAHHKLVLDSITKELGEKSISFIRIDGSTPSAERQLLCERFQASQQSCVAVLSITAANMGLTLHSAALVVFAELFWNPGVLIQAEDRVHRIGQTSNVDIHYLVAKGTADDYLWPMIQAKMNVLEQVGLSESNISENAESASFHSRDRQQLTITEMFQRSFDED---------------------------EMLALMDQDP------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VMX6-1", "uniprot_id": "SMAL1_DROME", "id": "Q9VMX6-1", "name": "SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A-like protein 1", "aln": "----MSTCSSSEIAEKKRIALAK-----------------------LQAKKSQLLASAPATNGKSTTSATGATQHANNGKSNPNQ----------------------------------------------------------------------------------------------------------------------------------------------PQAKSPLNFYRSPTGEQKKINRSGPTPGDNKSSSFLNALKAIKQTSNRELSRGAAHPYQRPNGGNERNKPTLSLSSDKEKPVAVLLGN------------------------------SITCNLYLISTHRFAAQTSGYHEQLVTVFKNMPTKCYDGQTRIWSFDLSDYQSLKTHAADLKPYVHMNGIPKKVLDLCG--------QPPVVPERSVLASIEPKLADQLMPFQQDGVCFAIAQKGRIMICDEMGLGKTYQALAVADYFKDDWPLLVCTTASTRDSWAKHIMDLLPKVPIHYVQVLNNNQLYVGEAKVLITSYNMMERHEDKLMQRKFGFIIFDESHTLKNSKAKCTTTAKRLTDQAKRVVLLSGTPALSRPLELFTQLQMIDGKFMN-FMEFTTRYCDGKQSTFGWDANGQSNLEELKVILHLKYMLRRTKVEVLPQLAEKNRETVVLDPALVWTNAETKETLDAFNKELKTAKGRATEEILLRFYARTAEVKTRAVCAYLKTLVKE-QKKFIIFAHHRVMMDAISDFLSGLKVHYIRIDGQTRSDHRSDSVDTFQKKSSCKVALLSLKACNSGITLTAAEIIVFAELDWNPSTLAQAESRAHRIGQTKPVICRYLIAHNTADDIIWNMLKNKQEVLSKVGIFAENLQKATHTAAPTSSHKIEEYFSPSTSTSLEPERNSIKQYFSTIPAKEPPEQNNNTEMTKVNKAESDIAAFFNDDDDEAFLELDI---------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :: . .* *::: ***: * *: . * .. : . : . . : : .:* ..:. . : .. : . *.: . :*: * :. . *:* : .: . * :: :**:* :: ** :** *.* *.:: .* : * *. : :* : . . .: *: ::.:*. .*****: ** **::: **:::.*:****** **:.:* :::.:***** ..:*.* :* : : **.: . ::*: ..: : . : * *:::: : : : * .:*:**** *** :: :* : . ****:*******:*** **:**: : :: * * ****.*: .:*** ...*** ***::*. **** * :**.**. *:*: *.: . : :.:.: * : . :: *: *: :***.* .: *: ::. ::**::****::::*:::. * : .*****.* * .*. : ** .. **:**:.*.* *:*: :* ::***** ***..* ***.*.******. * :**:*:.**** :* ::: * :** :.*: *:.: :.:: . : : . *:: : * ", "identical_positions": 192, "similar_positions": 228, "identity": "19.73%" }, { "cls_id": "homologset.agr.MGI:1859211", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D4AAV0-1", "uniprot_id": "D4AAV0_RAT", "id": "D4AAV0-1", "name": "", "aln": "MALHPRRVRLKPWLVAQVDSGLYPGLIWLHRDSKRFQIPWKHATRHSPQQEEENTIFKAWAVETGKYQEGVDDPDPAKWKAQLRCALNKSREFNLMYDGTKEVPMNPVKIYQVCDIPQPQGSVINPGSTGSAPWDEKDNDVDEDDEEDELEQSQ---------HHVPIQDTFPFLNINGSP---------MAPASVGNCSVGNCSPESVWPKTEP--LEMEVPQAPIQP------FYSSPELWISSLPMTDLDIKFQYRGKEYGQTMTVSNPQGCRLFYGDLGPMPDQEELFGPVSLEQVKFPGPEHITNEKQKLFTSKLLDVMDRGLILEVSGHAIYAIRLCQCKVYWSGPCAPSLAAPNLIERQKKVKLFCLETFLSELIAHQKGQIEKQPPFEIYLCFGEEWPDGKPLERKLILVQVIPVVARMIYEMFSGDFTRSFDSGSVRLQISTPDIKDNIVAQLKQLYRILQTQESWQ--PMQPAPSMQLPPALPAQ", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P97431-1", "uniprot_id": "IRF6_MOUSE", "id": "P97431-1", "name": "Interferon regulatory factor 6", "aln": "MALHPRRVRLKPWLVAQVDSGLYPGLIWLHRDSKRFQIPWKHATRHSPQQEEENTIFKAWAVETGKYQEGVDDPDPAKWKAQLRCALNKSREFNLMYDGTKEVPMNPVKIYQVCDIPQTQGSVINPGSTGSAPWDEKDNDVDEDEEEDELEQSQ---------HHVPIQDTFPFLNINGSP---------MAPASVGNCSVGNCSPESVWPKTEP--LEMEVPQAPIQP------FYSSPELWISSLPMTDLDIKFQYRGKEYGQTMTVSNPQGCRLFYGDLGPMPDQEELFGPVSLEQVKFPGPEHITNEKQKLFTSKLLDVMDRGLILEVSGHAIYAIRLCQCKVYWSGPCAPSLAAPNLIERQKKVKLFCLETFLSELIAHQKGQIEKQPPFEIYLCFGEEWPDGKPLERKLILVQVIPVVARMIYEMFSGDFTRSFDSGSVRLQISTPDIKDNIVAQLKQLYRILQTQESWQ--PMQPAPSMQLPQALPAQ", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O14896-1", "uniprot_id": "IRF6_HUMAN", "id": "O14896-1", "name": "Interferon regulatory factor 6", "aln": "MALHPRRVRLKPWLVAQVDSGLYPGLIWLHRDSKRFQIPWKHATRHSPQQEEENTIFKAWAVETGKYQEGVDDPDPAKWKAQLRCALNKSREFNLMYDGTKEVPMNPVKIYQVCDIPQPQGSIINPGSTGSAPWDEKDNDVDEEDEEDELDQSQ---------HHVPIQDTFPFLNINGSP---------MAPASVGNCSVGNCSPEAVWPKTEP--LEMEVPQAPIQP------FYSSPELWISSLPMTDLDIKFQYRGKEYGQTMTVSNPQGCRLFYGDLGPMPDQEELFGPVSLEQVKFPGPEHITNEKQKLFTSKLLDVMDRGLILEVSGHAIYAIRLCQCKVYWSGPCAPSLVAPNLIERQKKVKLFCLETFLSDLIAHQKGQIEKQPPFEIYLCFGEEWPDGKPLERKLILVQVIPVVARMIYEMFSGDFTRSFDSGSVRLQISTPDIKDNIVAQLKQLYRILQTQESWQ--PMQPTPSMQLPPALPPQ", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6PGZ7-1", "uniprot_id": "Q6PGZ7_DANRE", "id": "Q6PGZ7-1", "name": "", "aln": "MSSHPRRVRLKPWLVSQVDNATFPGLVWLDRDAKRFQIPWKHATRHTPQQEEENTIFKAWAVETGKYQEGVDEPDPAKWKAQLRCALNKSREFNLIYDGTKEVPMNPLKIYDVCDIPQTPS---NPGSVPTYETDGDEDDIPDTPEPPPPYASHGMSASPLAAVWTPPGSVSPLQPSSCAPPPALPPPPALPPPAATVLPAAAAPPANVWPKKEPEDVEMQPPPMEIQTPTALDNLFITPETWISSLPMTDLEVQFYYRGKEVCPPLTVSNPQGCRLFYGDLGPIVNQEELFGPVSLEQVRFPPTEHIANDKQRVFTSRLLDVMDRGLILEVSGHDIYAVRLCQCKVYWSGPCAPNPNAPNLIERQQKVKLFCLESFLSGVITHQRGQSSDAPLYDIHLCFGEEWPDGRPRERKLIMVQVVPVVARMISEMFSGDCTRSFDSGSVRLQISIPDIKDNIVTHLKQLYRLLQTHQGPENWPLPPGAALQLSSALHTQ", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*: ************:***.. :***:**.**:*************:*************************:**********************:***********:***:******. . ****. : * .::*: : * *: .* .. *: . :* :.*.:. ... ..* ****.** :**: * **. :: :** **********:::* ***** .:*****************: :*************:** .***:*:**::***:**************** ***:***************. ********:********:*** :*:**:** .. * ::*:**********:* *****:***:******* ****** ************** ********::******:***::. : *: * .::**. ** .*", "identical_positions": 316, "similar_positions": 88, "identity": "63.84%" }, { "cls_id": "homologset.agr.MGI:1859212", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q92985-1", "uniprot_id": "IRF7_HUMAN", "id": "Q92985-1", "name": "Interferon regulatory factor 7", "aln": "MALAPERAAPRVLFGEWLLGEISSGCYEGLQWLDEARTCFRVPWKHFARKDLSEADARIFKAWAVARGRWPPSSRGGGPPPEAETAER---AGWKTNFRCALRSTRRFVMLRDNSGDPADPHKVYALSRELCWREGPGTDQTEAEAPAAVPPPQGGPPGPFLAHTHAGLQAPGPLPAPAGDKGDLLLQAVQQSCLADHLLTASWGADPVPTKAPGEGQEGLPLTGACAGGPGLPAGELYGWAVETTPSPGPQPAALTTGEAAAPESPHQAEPYLSPSPSACTAVQEPSPGALDVTIMYKGRTVLQKVVGHPSCTFLYGPPDPAVRATDPQQVAFPSPAELPDQKQLRYTEELLRHVAPGLHLELRGPQLWARRMGKCKVYWEVGGPPGSASPSTPACLLPRNCDTPIFDFRVFFQELVEFRARQRRGSPRYTIYLGFGQDLSAGRPKEKSLVLVKLEPWLCRVHLEGTQREGVSSLDSSSLSLCLSSANSLYDDIECFLMELEQPA", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P70434-1", "uniprot_id": "IRF7_MOUSE", "id": "P70434-1", "name": "Interferon regulatory factor 7", "aln": "--MAEVRGVQRVLFGDWLLGEVSSGQYEGLQWLNEARTVFRVPWKHFGRRDLDEEDAQIFKAWAVARGRWPPSGVN-LPPPEAEAAERRERRGWKTNFRCALHSTGRFILRQDNSGDPVDPHKVYELSRELGSTVGPATENREEVSLSNALPTQGVSPGSFLARENAGLQTPSPLLS--SDAGDLLLQVLQYS----HILESESGADPVPPQAPGQEQD------------RVYEEPYAAWQVEAVPSPRPQQPALT----------------------------ERSLGFLDVTIMYKGRTVLQAVVGHPRCVFLYSPMAPAVRTSEPQPVIFPSPAELPDQKQLHYTETLLQHVSPGLQLELRGPSLWALRMGKCKVYWEVGSPMGTTGPSTPPQLLERNRHTPIFDFSTFFRELEEFRARRRQGSPHYTIYLGFGQDLSAGRPKEKTLILVKLEPWVCKAYLEGVQREGVSSLDSSSLGLCLSSTNSLYEDIEHFLMDLGQWP", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "F1QNG2-1", "uniprot_id": "F1QNG2_DANRE", "id": "F1QNG2-1", "name": "", "aln": "----MQSTNAKPQFGPWLIEQVESGQYEGLSMIGHD--IFRIPWKHNARRDLGDADVKIFKEWAIVSGKINEYPND--------------KAKWKTNFRCALHSLKSFEMLEDHSKDPDDQHKIYRIIRPQNHQEIKSAIQSAEAVQRQLPFIAEVYNASNHMSQDMELELLN-----LVETMDLNLHAVSQS------LKTYSQPNIQTTSSN------------------YFETTYSDDPCMQNNIPASVQQSHTT--------------------------VDQWNLDLEISISYRRTEVLKTRLCSSLIHFFYQCDPSELRG---EQIRFPTTDCLIDVKQIQYTKRILDSIQRGLQLEVNQYGIYGFRQDKCKVFVSTSDPCEIQKP--EPRKLQQNSKEQLLSFDKYIRDLLDFKE-NRGGSPDYTIYLCFGEKLHDGKPLEKKLITVKVVPLICRELHERAQMEGASSLRNDNVSLQIS-HNSLYDLINSLGLPSVE--", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : ** **: ::.** ****. :.. **:**** .*:**.: *.:*** **:. *: . *********:* * : .*:* ** * **:* : * .: : .. . *: . : ** *:.:. * * : .: ...: * . : * : *:::* *: **: : . *:* . :* : : **:. * * **::**: :* : **:**:. ::. * .****: ....* * . * :* . ::.* ::::* :*: .* *** ***** **:.* *:* **.*: **: * :*: * .* **.*** ...:.* :* ****: *: : : : ", "identical_positions": 122, "similar_positions": 114, "identity": "24.11%" }, { "cls_id": "homologset.agr.MGI:1859214", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9Z2M7-1", "uniprot_id": "PMM2_MOUSE", "id": "Q9Z2M7-1", "name": "Phosphomannomutase 2", "aln": "--MAT---------LCLFDMDGTLTAPRQKITEEMDGFLQ-KLRQKTKIGVVGGSDFEKLQEQL-GNDVVEKYDYVFPENGLVAYKDGKLLCKQNIQGHLGEDVIQDLINYCLSYIANIKLPKKRGTFIEFRNGMLNVSPIGRSCSQEERIEFYELDKKEHIRQKFVADLRKEFAGKGLTFSIGGQISIDVFPEGWDKRYCLRHLEHA-GYKTIYFFGDKTMPGGNDHEIFTDPRTVGYTVTAPEDTRRICEGLFP-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "F7F1X7-1", "uniprot_id": "F7F1X7_RAT", "id": "F7F1X7-1", "name": "Phosphomannomutase", "aln": "--MAT---------LCLFDMDGTLTAPRQKITKEMDGFLQ-KLRQKTKIGVVGGSDFEKLQEQL-GNDVVEKYDYVFPENGLVAYKDGKLLCKQNIQGHLGEAVIQDLINYCLSYIAKIKLPKKRGTFIEFRNGMLNVSPIGRSCSQEERIEFYELDKKEHIRQKFVADLRKEFAGKGLTFSIGGQISFDVFPDGWDKRYCLRHLEQA-GYKTIYFFGDKTMPGGNDHEIFTDPRTVGYTVTAPEDTRRICEELFP-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O15305-1", "uniprot_id": "PMM2_HUMAN", "id": "O15305-1", "name": "Phosphomannomutase 2", "aln": "--MAAPGP-----ALCLFDVDGTLTAPRQKITKEMDDFLQ-KLRQKIKIGVVGGSDFEKVQEQL-GNDVVEKYDYVFPENGLVAYKDGKLLCRQNIQSHLGEALIQDLINYCLSYIAKIKLPKKRGTFIEFRNGMLNVSPIGRSCSQEERIEFYELDKKENIRQKFVADLRKEFAGKGLTFSIGGQISFDVFPDGWDKRYCLRHVEND-GYKTIYFFGDKTMPGGNDHEIFTDPRTMGYSVTAPEDTRRICELLFS-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P07283-1", "uniprot_id": "PMM_YEAST", "id": "P07283-1", "name": "Phosphomannomutase", "aln": "MSIAEFAYKEKPETLVLFDVDGTLTPARLTVSEEVRKTLA-KLRNKCCIGFVGGSDLSKQLEQL-GPNVLDEFDYSFSENGLTAYRLGKELASQSFINWLGEEKYNKLAVFILRYLSEIDLPKRRGTFLEFRNGMINVSPIGRNASTEERNEFERYDKEHQIRAKFVEALKKEFPDYGLTFSIGGQISFDVFPAGWDKTYCLQHVEKD-GFKEIHFFGDKTMVGGNDYEIFVDERTIGHSVQSPDDTVKILTELFNL", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "Q9VTZ6-1", "uniprot_id": "PMM_DROME", "id": "Q9VTZ6-1", "name": "Phosphomannomutase", "aln": "MTTAALKRDE---ILLLFDVDGTLTMPRSVVTPEFEEFFYSRVKPRATIGIVGGSDLEKMFEQLNGRKILNEFDFIFPENGLVQIEGGKEVGKQNIIMHLGEETVKRFINFVLRYLSELDVPIKRGTFIEFRNGMMNVCPIGRQCTREERNMFAEYDIEHKVREKMIKDLKQEFADVDLTYSIGGQISFDVFPHGWDKTYCLRHIEAHYKFKEIHFFGDKTEPGGNDYEIYSDPRTISHRVYTPKDTQRILTEILEL", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * * ***:***** .* :: *. : ::: : **.*****:.* *** * .:::::*: *.****. . ** : *.: *** : : : * *::::.:* :****:******:**.****..: *** * . * :.::* *:: *::**.. .**:*******:**** **** ***:*:* :* *:****** ****:**: * **:.: * :*.** :* :: ", "identical_positions": 109, "similar_positions": 70, "identity": "42.41%" }, { "cls_id": "homologset.agr.MGI:1859216", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P30560-1", "uniprot_id": "V1AR_RAT", "id": "P30560-1", "name": "Vasopressin V1a receptor", "aln": "MSFPRGSQDRSVGNSSPWWPLTTEGSNGSQEAARLGEGDSPLGDVRNEELAKLEIAVLAVIFVVAVLGNSSVLLALHRTPRKTSRMHLFIRHLSLADLAVAFFQVLPQLCWDITYRFRGPDWLCRVVKHLQVFAMFASAYMLVVMTADRYIAVCHPLKTLQQPARRSRLMIATSWVLSFILSTPQYFIFSVIEIEVNNGTKTQDCWATFIQPWGTRAYVTWMTSGVFVAPVVVLGTCYGFICYHIWRNIRGKTASSRHSKGDKGSGEAVGPFHKGLLVTPCVSSVKSISRAKIRTVKMTFVIVSAYILCWAPFFIVQMWSVWDENFIWTDSENPSITITALLASLNSCCNPWIYMFFSGHLLQDCVQSFPCCHSMAQKFAKDDSDSMSRRQTSYSNNRSPTNSTGMWKDSPKSSKSIRFIPVST", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q62463-1", "uniprot_id": "V1AR_MOUSE", "id": "Q62463-1", "name": "Vasopressin V1a receptor", "aln": "MSFPRGSHDLPAGNSSPWWPLTTEGANSSREAAGLGEGGSPPGDVRNEELAKLEVTVLAVIFVVAVLGNSSVLLALHRTPRKTSRMHLFIRHLSLADLAVAFFQVLPQLCWDITYRFRGPDWLCRVVKHLQVFAMFASSYMLVVMTADRYIAVCHPLKTLQQPARRSRLMIAASWGLSFVLSIPQYFIFSVIEFEVNNGTKAQDCWATFIPPWGTRAYVTWMTSGVFVVPVIILGTCYGFICYHIWRNVRGKTAS-RQSKGGKGSGEAAGPFHKGLLVTPCVSSVKSISRAKIRTVKMTFVIVSAYILCWTPFFIVQMWSVWDTNFVWTDSENPSTTITALLASLNSCCNPWIYMFFSGHLLQDCVQSFPCCQSIAQKFAKDDSDSMSRRQTSYSNNRSPTNSTGTWKDSPKSSKSIRFIPVST", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P37288-1", "uniprot_id": "V1AR_HUMAN", "id": "P37288-1", "name": "Vasopressin V1a receptor", "aln": "MRLSAGPDAGPSGNSSPWWPLATGAGNTSREAEALGEGNGPPRDVRNEELAKLEIAVLAVTFAVAVLGNSSVLLALHRTPRKTSRMHLFIRHLSLADLAVAFFQVLPQMCWDITYRFRGPDWLCRVVKHLQVFGMFASAYMLVVMTADRYIAVCHPLKTLQQPARRSRLMIAAAWVLSFVLSTPQYFVFSMIE--VNNVTKARDCWATFIQPWGSRAYVTWMTGGIFVAPVVILGTCYGFICYNIWCNVRGKTAS-RQSKGAEQAG---VAFQKGFLLAPCVSSVKSISRAKIRTVKMTFVIVTAYIVCWAPFFIIQMWSVWDPMSVWTESENPTITITALLGSLNSCCNPWIYMFFSGHLLQDCVQSFPCCQNMKEKFNKEDTDSMSRRQTFYSNNRSPTNSTGMWKDSPKSSKSIKFIPVST", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* :. *.. . *********:* ..* *:** ****..* ***********::**** *.*********************************************:************************.****:*********************************::* ***:** ****:**:** *** **::******* ***:********.*:**.**::**********:** *:****** *:*** : :* .*:**:*::************************:***:**:****:******* :**:****: ******.*****************************:.: :** *:*:******** ************ ***********:******", "identical_positions": 335, "similar_positions": 55, "identity": "79.01%" }, { "cls_id": "homologset.agr.MGI:1859217", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O96015-1", "uniprot_id": "DNAL4_HUMAN", "id": "O96015-1", "name": "Dynein axonemal light chain 4", "aln": "MGETEGKKDEADYKRLQTFPLVRHSDMPEEMRVETMELCVTACEKFSNNNESAAKMIKETMDKKFGSSWHVVIGEGFGFEITHEVKNLLYLYFGGTLAVCVWKCS", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9DCM4-1", "uniprot_id": "DNAL4_MOUSE", "id": "Q9DCM4-1", "name": "Dynein axonemal light chain 4", "aln": "MGETEGKKEEADYKRLQTFPLVRHSDMPEEMRVETMELCVTACEKFSNNNESAAKMIKETMDKKFGSSWHVVIGEGFGFEITHEVKNLLYLYFGGTLAVCVWKCS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8I6A5P7-1", "uniprot_id": "A0A8I6A5P7_RAT", "id": "A0A8I6A5P7-1", "name": "Dynein light chain", "aln": "MGETEGKKEEADYKRLQTFPLVKHSDMPEEMRMETMELCVTACEKFSNNNESAAKMIKETMDKKFGSCWHVVIGEGFGFEITHEVKNLLYLFFGGTLAVCVWKCS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A1Z8T9-1", "uniprot_id": "A1Z8T9_DROME", "id": "A1Z8T9-1", "name": "Dynein light chain", "aln": "MADEEAGK-EGEKKIVHVYPLVKHTDMNEEMRIEAIELSITACEKYSSNYEHAAKIIKENMDKKFGIYWHVVVGEGFGFEVSYETENILYLFFAGNLAIVLWKCS", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*.: *. * *.: * ::.:***:*:** ****:*::**.:*****:*.* * ***:***.****** ****:*******:::*.:*:***:*.*.**: :****", "identical_positions": 62, "similar_positions": 32, "identity": "59.05%" }, { "cls_id": "homologset.agr.MGI:1859251", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0ABK0LUS4-1", "uniprot_id": "A0ABK0LUS4_RAT", "id": "A0ABK0LUS4-1", "name": "", "aln": "MAALTDVQRLQSRVEELERWVYGPGGTRGSRKVADGLVKVQVALGNIASKRERVKILYKKIEVLIKYLDPEYIDRIAIPEASKLQFILAEEQFILSQVALLEQVNTLVPVLDSASIKAVP-EHAARLQRLAQIHIQQQ---------------------------------------------------------------DQCVEITE----------ESKALLEEYNKTTMLLSKQLVQWDELL----------CQLEAAKQVKPAAE---------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9Z0Y1-1", "uniprot_id": "DCTN3_MOUSE", "id": "Q9Z0Y1-1", "name": "Dynactin subunit 3", "aln": "MAALTDVQRLQSRVEELERWVYGPGGTRGSRKVADGLVKVQVALGNIASKRERVKILYKKIEDLIKYLDPEYIDRIAIPEASKLQFILAEEQFILSQVALLEQVNALVPVLDSASIKAVP-EHAARLQRLAQIHIQQQ---------------------------------------------------------------DQCVAITE----------ESKALLEGYNKTTMLLSKQFVQWDELL----------CQLEAAKQVKPAEE---------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O75935-1", "uniprot_id": "DCTN3_HUMAN", "id": "O75935-1", "name": "Dynactin subunit 3", "aln": "MAGLTDLQRLQARVEELERWVYGPGGARGSRKVADGLVKVQVALGNISSKRERVKILYKKIEDLIKYLDPEYIDRIAIPDASKLQFILAEEQFILSQVALLEQVNALVPMLDSAHIKAVP-EHAARLQRLAQIHIQQQ---------------------------------------------------------------DQCVEITE----------ESKALLEEYNKTTMLLSKQFVQWDELL----------CQLEAATQVKPAEE---------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8I5YB95-1", "uniprot_id": "A0A8I5YB95_RAT", "id": "A0A8I5YB95-1", "name": "", "aln": "MAALTDVQRLQSRVEELERWVYGPGGTRGSRKVADGLVKVQVALGNIASKRERVKILYKKIEDLIKYLDPEYIDRIAIPEASKLQFILAEEQFILSQVALLEQVNTLVPMLDSASIKAVP-EHAARLQRLAQIHIQQQVWKMRGLEGKADTMRHPVSCVPSPLPTITPPATHCHPHCPLSHPPCTLSHPLLPTVTLTAHCHTPCYPLSPSLPTVTTPLHTSHSPLPTVTHPTHPLSPPTATVTSPLPSHTHTPTAQCHTPTTHCHTPLPPTLTHIPTSHCHLPRDLGLYVVCGGISSISKCSREGKGLA", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9W1V8-1", "uniprot_id": "Q9W1V8_DROME", "id": "Q9W1V8-1", "name": "", "aln": "---MEALDILEKRIDALTRVLGPVQDSEVGEGVVDALCSAHAILGEATTGSAALQQCVKRSDELEKYLDPNFLEEHQQVRS-KEVYLQAVAPELHTQAEQLERIKQLEPALGAEYFRSIPAECLEQLKGITQNNGEYA---------------------------------------------------------------QQSELIEES----------LVLAMKRYGEIQAGLLSSLDAMSERLD----------QVEERMEQRKRAELSKDVPPKD------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : :: *: *:: * * : .:. .. *.*.* ..:. **: :: :: *: : * *****::::. : * :: * : :*. **::: * * *.: ::::* * :*: ::* : : . : : . * . * : ", "identical_positions": 30, "similar_positions": 57, "identity": "9.71%" }, { "cls_id": "homologset.agr.MGI:1859252", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I6AUE2-1", "uniprot_id": "A0A8I6AUE2_RAT", "id": "A0A8I6AUE2-1", "name": "Formin-2", "aln": "--------------------------------------------------------MGNQDGK---------------------------------------------LKRSAGDASHE---------------------GGGGGAEDAAG-PR---------------------------DAETTK-----KASGSKKALGKHG--KGGGGSG---ETSKKKSKSDS-RASVFSNLRIRKNLGKGKGAG-DSREDVLDSQALPIGELDSAHSIVTKTPDLSLSAEETGLSDTECADPFEVIHPGGSRPAEAGVGIQAIAEDLETAAGAQDGQRTSSGSDTDIYSFHSATEQEDLLSDIQQAIRLQQQQQQQQKLLLQD---------SEEPAAPPT----AISPQPGAFLG------LDQFLLGTS---------SEAKKDTVQAPPVRPDLPETTKS--LVPEHPPSSGSHLASETPGYATAHSAVTD------TLSSPAFTFPEVPEAGPGEGAAGVPPAGTGDTDEECE---------------EDAFEDAPRGSPGEEWAPEV-----EEASQRLEEEPEEGMRGPIIPAVASLPGSPAPSPRCFKPYPLITPCYIKTTTRQLSSPNHSPSQSPNQSPRIKKRPDPSVSRSPRTALASAATPAKKHRLEGGLVGGLSRSADWTEELGARTPGAGGSVHLLGRGATADDS-GGGSPVLAAKAPGAPATADGFQNVFTGRTLLEKLFSQQENGPPE----EAEKFCSRIIAMGLLLPFSDCFREPCNQNAGSSSAPFDQDQLYTWAAVSQPTHSMDYSEGQFPRREPSTWRPSKLPDEEPSPK--DIDTAYLEEPQSSILESPKKCSNGVQQEVFD-------VKSEGQATVIQQLEQTIEDLRTKIAALEKQYPSLDLEGPR----LENGLTASADVSLDALGLHGKVAHPPRTLEAKSIQTSPTEEDRILTLPPPKAPPEGLPGPPAAESGESALLTSSSGPQTKFCSEISLIVSPRRISVQLDAQPAMQSTSQLPPPPSLLGADSQGQP-SQP--SLHPELETSHEHSVFSSFENSCNIPPAPPLPCTESSSFMPGLGTAIPPPPCLSDITVPALPSPTAPALQLTNLQGPQMLPTPPQ-----------------------------------------------------PPSLSGPGVPPPP--------PPPPLPGVGIPPPPPLPGMGIPPPPPLPGMGIPPPPPLPG-VEIPPPPPLPGGGIPPPPPLPGGGIPPPPPLPGGGIPP----------PPPPLPGVGIPPPPPLPGVGIPPPPPLPGVVIPPPPPPP---------------------------------------PPPLPGVGIPPPPPLPGMGIPPPPPLPGVGIPPPPALPGVAIPPPPPLPGMGVPPPAP--------------PPPGAGIPPPPQLPGSGLPLSSQDGSSTLPAAPQGCGFLFPPLPTGLFGLGMNQDRVARKQPIEPCRPMKPLYWTRIQLHSKRDSSPSLIWEKIEEPSID-CHEFEELFSKTAVKERKKPISDTISKTKAKQVVKLLSNKRSQAVGILMSSLHLDMKDIQHAVVNLDNSVVDLETLQALYENRAQSDELEKIEKHSRSSKDKENAKSLDKPEQFLYELSLIPNFSERVFCILFQSTFSESICSIRRKLELLQKLCETLKNGPGVMQVLGLVLAFGNYMNAGNKTRGQADGFGLDILPKLKDVKSSDNSRSLLSYIVSYYLRN-FDEDAGKEQCVFPLSEPQELFQASQMKFEDFQKDLRKLKKDLKACEVEAGKVYQVSSEEHKQPFKENMEQFISQAKIDQETQETALTETHKCFLETTAYYFMKPKLGEK---EVSPNVFFSVWHEFSSDFKDSWKKENKLILQERVKEAEEVCRQKKGKSLYKVKPRHDSGIKAKISMKT---", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9JL04-1", "uniprot_id": "FMN2_MOUSE", "id": "Q9JL04-1", "name": "Formin-2", "aln": "--------------------------------------------------------MGNQDGK---------------------------------------------LKRSAGDASHE---------------------GGG--AEDAAG-PR---------------------------DAEITK-----KASGSKKALGKHG--KGGGGSG---ETSKKKSKSDS-RASVFSNLRIRKNLTKGKGAC-DSREDVLDSQALPIGELDSAHSIVTKTPDLSLSAEETGLSDTECADPFEVIHPGASRPAEAGVGIQATAEDLETAAGAQDGQRTSSGSDTDIYSFHSATEQEDLLSDIQQAIRLQQQQQQ--KLLLQD---------SEEPAAPPT----AISPQPGAFLG------LDQFLLGPR---------SEAEKDTVQALPVRPDLPETTKS--LVPEHPPSSGSHLTSETPGYATAPSAVTD------SLSSPAFTF---PEAGPGEGAAGVPVAGTGDTDEECE---------------EDAFEDAPRGSPGEEWVPEV-----EEASQRLEKEPEEGMRESITSAVVSLPGSPAPSPRCFKPYPLITPCYIKTTTRQLSSPNHSPSQSPNQSPRIKKRPDPSVSRSSRTALASAAAPAKKHRLEGGLTGGLSRSADWTEELGVRTPGAGGSVHLLGRGATADDS-GGGSPVLAAKAPGAPATADGFQNVFTGRTLLEKLFSQQENGPPE----EAEKFCSRIIAMGLLLPFSDCFREPCNQNAGSSSAPFDQDQLYTWAAVSQPTHSMDYSEGQFPRREPSMWPSSKLPEEEPSPK--DVDT----EPKSSILESPKKCSNGVQQEVFD-------VKSEGQATVIQQLEQTIEDLRTKIAELEKQYPALDLEGPRGLSGLENGLTASADVSLDALVLHGKVAQPPRTLEAKSIQTSPTEEGRILTLPPPKAPPEGLLGSPAAASGESALLTSPSGPQTKFCSEISLIVSPRRISVQLDAQ-QIQSASQLPPPPPLLGSDSQGQP-SQP--SLHTESETSHEHSVSSSFGNNCNVPPAPPLPCTESSSFMPGLGMAIPPPPCLSDITVPALPSPTAPALQFSNLQGPEMLPAPPQ-----------------------------------------------------PPPLPGLGVPPPP--------PAPPLPGMGIPPPPPLPGMGIPPPPPLPGMGISPLPPLPG-MGIPPPPPLPGVGIPPPPPLPGVGIPPPPPLPGVGIPP----------PPP-LPGVGIPPPPPLPGVGIPPPPPLPGVGIPPP--------------------------------------------PPLPGVGIPPPPPLPGVGIPPPPPLPGSGIPPPPALPGVAIPPPPPLPGMGVPPPAP--------------PPPGAGIPPPPLLPGSGPPHSSQVGSSTLPAAPQGCGFLFPPLPTGLFGLGMNQDRVARKQLIEPCRPMKPLYWTRIQLHSKRDSSPSLIWEKIEEPSID-CHEFEELFSKTAVKERKKPISDTISKTKAKQVVKLLSNKRSQAVGILMSSLHLDMKDIQHAVVNLDNSVVDLETLQALYENRAQSDELEKIEKHSRSSKDKENAKSLDKPEQFLYELSLIPNFSERVFCILFQSTFSESICSIRRKLELLQKLCETLKNGPGVMQVLGLVLAFGNYMNAGNKTRGQADGFGLDILPKLKDVKSSDNSRSLLSYIVSYYLRN-FDEDAGKEQCVFPLAEPQELFQASQMKFEDFQKDLRKLKKDLKACEAEAGKVYQVSSAEHMQPFKENMEQFISQAKIDQESQEAALTETHKCFLETTAYYFMKPKLGEK---EVSPNVFFSVWHEFSSDFKDAWKKENKLILQERVKEAEEVCRQKKGKSLYKVKPRHDSGIKAKISMKT---", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9NZ56-1", "uniprot_id": "FMN2_HUMAN", "id": "Q9NZ56-1", "name": "Formin-2", "aln": "--------------------------------------------------------MGNQDGK---------------------------------------------LKRSAGDALHE---------------------GGGG-AEDALG-PR---------------------------DVEATK-----KGSGGKKALGKHG--KGGGGGGGGGESGKKKSKSDS-RASVFSNLRIRKNLSKGKGAG-GSREDVLDSQALQTGELDSAHSLLTKTPDLSLSADEAGLSDTECADPFEVTGPGGPGPAEARVGGRPIAEDVETAAGAQDGQRTSSGSDTDIYSFHSATEQEDLLSDIQQAIRLQQQQQQQLQLQLQQQQQQQQLQGAEEPAAPPT----AVSPQPGAFLG------LDRFLLGPSGG----AGEAPGSPDTEQALSALSDLPESLAAEPREPQQPPSPGGLPVSEAPSLPAAQPAAKD------SPSSTAFPF---PEAGPGEEAAGAPVRGAGDTDEEGE---------------EDAFEDAPRGSPGEEWAPEVG----EDAPQRLGEEPEEEAQGPDAPAAASLPGSPAPSQRCFKPYPLITPCYIKTTTRQLSSPNHSPSQSPNQSPRIKRRPEPSLSRGSRTALASVAAPAKKHRADGGLAAGLSRSADWTEELGARTPRVGGSAHLLERGVASDSG-GGVSPALAAKASGAPAAADGFQNVFTGRTLLEKLFSQQENGPPE----EAEKFCSRIIAMGLLLPFSDCFREPCNQNAQTNAASFDQDQLYTWAAVSQPTHSLDYSEGQFPRRVPSMGPPSKPPDEEHRLE--DAET----ESQSAVSETPQKRSDAVQKEVVD-------MKSEGQATVIQQLEQTIEDLRTKIAELERQYPALDTEVASGHQGLENGVTASGDVCLEALRLEEKEVRHHRILEAKSIQTSPTEEGGVLTLPP----VDGLPGRPPCPPG------AESGPQTKFCSEISLIVSPRRISVQLDSHQPTQSISQPPPPPSLLWSAGQGQPGSQPPHSISTEFQTSHEHSVSSAFKNSCNIPSPPPLPCTESSSSMPGLGMVPPPPPPLPGMTVPTLPSTAIP--QPPPLQGTEMLPPPPPPLPGAGIPPPPPLPGAGILPLPPLPGAGIPPPPPLPGAAIPPPPPLPGAGIPLPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPG-AGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGVGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPRVGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGVGIPPPPPLPGVGIPPPPPLPGAGIPPPPPLPGMGIPPAPAPPLPPPGTGIPPPPLLPVSGPPLLPQVGSSTLP-TPQVCGFLPPPLPSGLFGLGMNQDKGSRKQPIEPCRPMKPLYWTRIQLHSKRDSSTSLIWEKIEEPSID-CHEFEELFSKTAVKERKKPISDTISKTKAKQVVKLLSNKRSQAVGILMSSLHLDMKDIQHAVVNLDNSVVDLETLQALYENRAQSDELEKIEKHGRSSKDKENAKSLDKPEQFLYELSLIPNFSERVFCILFQSTFSESICSIRRKLELLQKLCETLKNGPGVMQVLGLVLAFGNYMNGGNKTRGQADGFGLDILPKLKDVKSSDNSRSLLSYIVSYYLRN-FDEDAGKEQCLFPLPEPQDLFQASQMKFEDFQKDLRKLKKDLKACEVEAGKVYQVSSKEHMQPFKENMEQFIIQAKIDQEAEENSLTETHKCFLETTAYFFMKPKLGEK---EVSPNAFFSIWHEFSSDFKDFWKKENKLLLQERVKEAEEVCRQKKGKSLYKIKPRHDSGIKAKISMKT---", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M3B4X8-1", "uniprot_id": "A0A8M3B4X8_DANRE", "id": "A0A8M3B4X8-1", "name": "", "aln": "MQPVQMLEAPG-----------FRQKLLEALS-------------LGRRQKYCLPHMQREDPQPHTHTLAHVPGARRPSLPHSFCREEESESELLYLSFVTACSSAPLSSSSLSSASSS---------------------SSSSDSESSSWSPRRRHTHSSHGLK-------PPPLIMGNQDAKLKR-----DAGAAADDNGAYEGAKKGKKSHGKGEGGKKKNKSD--RSSVFPHIRKRKNQNKLKGILSGSKEDALDSQHD---ELDSAPSLCNKTPDLSG-------------DELDVESERPRLVADSRQATLDANEDEEKIR--------SSGSDTDMYSFHSAAEQEDLLADIQQAIRMKQGVMLASPVELPWERNGK----QTTGSDAKN----TPTPDSEPFTV------LEAIPKAENG-------CVSALEDKETTISRNEALCAPVAVETITKDPPPPPPPPPAPPAVTMTPSTSNLTA------SFESAVEAVE---EQQPEDSTPDAPPS----ADTISE---------------EDHLGSA--GSLECVSAIEVP----EEIQRRKSSVSFSQWSQQESPLATRLLKS------SVKPYPPISTSYIKTTTRQLSSPSCSPGPSPSHSPLFTRR-------EHAVTLARAERRRVKRQRSYSITGPISRSADWTEEIRTLPPKTTGSADYLEYGGSEGTLRSDRTLSASQRASATRASTCSFQEVFTGRTLLERFFQQQDSSEPE----EAEKLCSKILAMGLLLPFSDCFRETYSS-SGHLAPQFDQDQLYTWAAVSQPPPSLERLEGHLPGHLKGLWIPTQPGEEEQPLAKYTEDAVEEPEEHQAVVSDLKKHQEEEIRQIQEDSVLKTVRLKQEHICVIEQLEQTIEDLRSKIAELEKQQPLPEREVETQDQECGGEEGLHPDVCHVDLQTENTSLLP---LEAKSVQTSPVDESYRFKVPP--------------------------------------------VEVRRDSLLASQTESQ----------------------------------AASQSFVCICQQQTS----------------TSAPPPP----------------------------------------------------------------------------------------PPLPGVCAPPPP----------PPLPGVCVPTPPPLPGVCPPPPP----------PPLPGVCAIPPPPPLPGASLPPP----------PPPLPCLSVPP---------------------PPPPLPGMGAPPPP------------------------------------------------------PPLPGLSAPPPP----------PPLPGMGVPPPPPLPLTHTGPAPP------PPPPP--------------------IPPSMAPGACAPPLAFGFGS------------LPPPLPLGLFALGAVQEKPPRKCIVEPPRPMKPLYWTRIQLHTKKDSN-AVVWDTIEEPSVD-FDEFVDLFSKTAVKEKKKPLSDTISRSKTKQVVKLLNTKRSQAVGILMSSLHLDMKDIQHAILNLDNTVVDLETLQALYENRAQQDELDKIEKHIKSSKDKEGTKPLDKPEQFLHQLSQIPNFSGRVFCILFQSTFSECITSVQRKLQILQKVCKTLQSGSGVLQVLGLVLAFGNFMNGGNRTRGQADGFTLDILPKLKDVKSSDNSKSLLAYIVSYYLRH-FDEDAGRETCVFPLPEPHDLFQASQMKFEDFTKDLLRLRKDLRACTAEVEKVCSVSTEEHLQPFKEKMEAFVTEAKTELEGQEKQLSDTHKLFLDLCVFFSVKAKSGEK---EVSPNTFFSVWHEFCTDFKDTWKKENKLILQERLKAAEECFRQVKEKATYSVKPKHASGIKAKLGMKI---", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0ACD6B718-1", "uniprot_id": "A0ACD6B718_DANRE", "id": "A0ACD6B718-1", "name": "", "aln": "MQTIQTIEMQLPVLRESFHSSPFRERAKERRKSSLSNLIRRQQQQLLREQQQSVLHQKQQPSSPLQGHAAHAQLVRSSSSPLCDLAEQIGELEKVRGIGRQGELSHRQSSDTASQPASSQQLLLAVKREREGLLREGEKVQGSTEREREEKRERESQSERTRSQHGLIAKGVRLLRIMGNQEAKQKKPTVTTGAEGEGNGAGTEDHVKKIKKSKSSAESGKKKSKSEGSKGSVFSNIRIRKGLSR----KVLSKEDVLDGGIR----IKPADANGNSNGGISG--------------DESCMPDSKQLTAESRQSTLDTTEDDVERETE------GSGSDTDLCSYHSAAEAQDLLSDIQRTIRQMEGVDERQNCHSEDKERQVGFEGHVEVTHGPTRGSLACEGEPEKLEGASDSKYLNLICSGDTTGGVITSKLKIESDGKVADIPNKADHLSSLSSDYSIQDAVPETNSVQDARAFTHSTSNYSFQDNTGTSTSYESAEEILESSSLSSPLEECHYDSNSLTQSLEVGLNSSNHMSKINRVIFVPQKSISSVELNVDGDGPVEEVDRGFSTQPRRKSSAASMTQWSSENFLGSGSRPRRTSSANLGVKPYPTIQTSYVKTTTRQLTSPIISPFTTPSPSPMCPRKVG--LEFGTGQGPYRAGSWRARRQRSCSIAGPVGCHEEWCEVIHDQS-------ELIESGFQTDRS---------------RQTTSTFPDVFSGSSLLERCFLQWSSSEDDSAMQDIERFCSRILDLGILQPFSDCIREPSTGSDVTDKPTFNKDQLYTWAPMGQH-------DIRTPGRLQRIWPPTLTAAQDGSTG-----------QSGSVLE--------------------------GSSVSIQELEQTIEELLEKISEIEKDNHVVDGKLGR-----KDREVAGFNQTIKQTKVNGQRVLH----HVKAIQTSPVEEAFKFPVPL---------------------------------------------SHQSQTPKLSDSATS----------------------------------PMGLPYTCSCQRTTS---------------------------------------------------------------------------------------------------------------QPLS---TPPPP----------------QLPPPPPLSGMTPPKPTG----------------VIPPPPPLPG-FVPPP--------------PVVGKAP---------------------PPPPLPGMVPPPPP-------------------------------------------------------PLPGMAPPPPP-----------PFPGMTPPPPPPPPGCGP-------------------------------------PPPPLPPGIGP----------------------PPPFMGMGPPGMAHESVPLKAVIEPPRPMKPLYWTRIQLHAKKDAKSALVWENVQEPSVD-FDEFVEMFAKSAVKEKKKPISDTITKSKAKQVVKLLSNKRSQAVGILMSSLHLDMKDIQNAILKMDCTVVDLETLQALYENRAQKEEMDQIEKHVKSSKDKEKPKPLDKPEQFLLQLSEVPQFSERVFCILFQSTFTECVTSVQRKLETLGRVCTALQSGQAVLQILGLVLAFGNIMNGGNRSRGQADGFSLDILPKLKDVKSSDNSQSLLSYIVAYYLRH-FDEDAGKETCTYPLPEPQDLFQASQMKFEDFQRDLRKLRKDLNACSAEREKVCNISSDEHLQPFKDKMDDFLTKAKTELELQEKQLTDTQRIFLELSVFFSVKPKAGEK---EVSPNTFFTVWHEFSSDFKELWKRENKSLLQERLKAAEETFKQAREKATYNVKPKQASGIKAKLGQKM---", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q24120-1", "uniprot_id": "CAPU_DROME", "id": "Q24120-1", "name": "Protein cappuccino", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MALQLGKKLAQVLGSG-----------------------------------------------AGSPLTPGTMEPCAAGSGSPLAN------------------GELFNVSKAKKVELQNLSSRFTAAVTQTPPGVTSSTPNESGVTG------------------------------------------------------PAGPLGATTSSPSLETQSTVIISFKSSQTPVQSQTNSAASENVEDDTAPLPLPP--------------------PPPGFGTPTTPLLSS------------------------------------------------------------------------------------------NVLKKVASFTVEKSSAGNNSSNPPNLCPTSDETTLLATPCSSSLTVATLPPEIAVGAAAGGVAGGAGSRRGSSYVPEKLS----------------------------------FAAYEKFEGQMLIKWLISTMQSNPKSSSGD---ANQELFNTLALQFCNNLKYVGVLKQISNEHLDCG---FSPYEMYQWTHTEQPTTSLPLTPGKLDKVAAWPFSSTPSGIRALESAS---------------------------------------LASLGAGGVAGSLATIATASTASSDNQKTLQQILKKRLLNCTTLAEVHAVVNELLSSVDEPPRRPSKRCVNLTELLNASEATVYEYNKTGAEG---------------------------------------------CVKSFTDAETQTESE----------------------------DCEGTCKCGQSSTKVSDNESAKE------------------------------------------------------------------------------------------------------------DGEKPHAVAPPPP------------------PPPPPLHAFVAPPPPPPP--------------PPPPPPPLANYGAPPP-------------------PP---------------------PPPPGSGSAPPPPPP-----------------------------------------------------APIEGGGGIPPPP------PPMSASPSKTTISPAPLPDPAEGNWFHRTNTMRKSAVN---------------------PPKPMRPLYWTR-------------------IVTSAPPAPRPPSVANSTDSTEN--SGSSPDEPPAANGADAPPTAPPATKEIWTEIEETPLDNIDEFTELFSRQAIAPVSKPKELKVKRAKS---IKVLDPERSRNVGIIWRSLHVPSSEIEHAIYHIDTSVVSLEALQHMSNIQATEDELQRIKEAAG------GDIPLDHPEQFLLDISLISMASERISCIVFQAEFEESVTLLFRKLETVSQLSQQLIESEDLKLVFSIILTLGNYMNGGNRQRGQADGFNLDILGKLKDVKSKESHTTLLHFIVRTYIAQRRKEGVHPLEIRLPIPEPADVERAAQMDFEEVQQQIFDLNKKFLGCKRTTAKVLAASRPEIMEPFKSKMEEFVEGADKSMAKLHQSLDECRDLFLETMRFYHFSPKACTLTLAQCTPDQFFEYWTNFTNDFKDIWKKEITSLLNELMKKSKQAQIESRRNVSTKVEKSGRISLKERMLMRRSKN", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :: * : . . : . .: * . .* ::* : : :: . . . .: * . : : * : :*. .. .*. .* . .:.. . . : * : *:. : ... : : * : : : : : . ::: . *. ::* *: * : .: . .* . : . . . . . :.. * : : :: :. . .: .. . **** *.**** . * *. ******.. *** .* **** .* **** *: * . *** . *. .*.. * ** .. . . :. . : . * :* . : .. . :* ::*..:* .** ::*:: *: .** . .:.::*: :*:*. :**: ***: ***: .:*::*: ::* :**.**:** : : :* .:*:::*:: .**:***** ::* :. * *: **:**: * *.: : ***: : ::. * .. : ::.::*::** **.**: ******* **** *******.:. :** :** *: : .*.. *:.** :: :*:**.**:. ::: *.*.: .* ** * * :***.:*: *: *. . . * : : **: :: ...* : :*: ** * :* .***: **:* . :*:* :* ::: : : : .:: .:* :: : ", "identical_positions": 183, "similar_positions": 263, "identity": "9.32%" }, { "cls_id": "homologset.agr.MGI:1859268", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P78386-1", "uniprot_id": "KRT85_HUMAN", "id": "P78386-1", "name": "Keratin, type II cuticular Hb5", "aln": "----MSCRSYRISSGCGVTRNFSSCSAVAPKTGNRCCISAAPYRGVSCYRGLTGFGSRSLCNLGSCGPRIAVGGFRAGSCGRSFGYRSGGVCGPSPPCITTVSVNESLLTPLNLEIDPNAQCVKQEEKEQIKSLNSRFAAFIDKVRFLEQQNKLLETKWQFYQNQRCCESN----LEPLFSGYIETLRREAECVEADSGRLASELNHVQEVLEGYKKKYEEEVALRATAENEFVVLKKDVDCAYLRKSDLEANVEALVEESSFLRRLYEEEIRVLQAHIS-----DTSVIVKMDNSRDLNMDCIIAEIKAQYDDVASRSRAEAESWYRSKCEEMKATVIRHGETLRRTKEEINELNRMIQRLTAEIENAKCQRAKLEAAVAEAEQQGEAALSDARCKLAELEGALQKAKQDMACLLKEYQEVMNSKLGLDIEIATYRRLLEGEEHRLCEGVGSVNVCVSSSRGGVSCGGLSYSTTPGRQITSGPSAIGGSITVVAPDSCAPCQPRSSSFSCGSSRSVRFA", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9Z2T6-1", "uniprot_id": "KRT85_MOUSE", "id": "Q9Z2T6-1", "name": "Keratin, type II cuticular Hb5", "aln": "----MSCRSYRISPGCGVTRNFSSCSAVAPKTGNRCCISAAPFRGVSCYRGLTGFSSRSLCNPSPCGPRMAVGGFRSGSCGRSFGYRSGGVCGPSPPCITTVSVNESLLTPLNLEIDPNAQCVKYEEKEQIKCLNSKFAAFIDKVRFLEQQNKLLETKWQFYQNRKCCESN----LEPLFGGYIEALRREAECVEADSGRLAAELNHVQEAMEGYKKKYEEEVALRATAENEFVVLKKDVDCAYLRKSDLEANVEALVEESSFLKRLYEEEVCVLQAHIS-----DTSVIVKMDNSRDLNMDCVVAEIKAQYDDVASRSRAEAESWYRTKCEEMKATVIRHGETLRRTKEEINELNRMIQRLTAEIENAKCQRAKLEAAVAEAEQQGEAALADARCKLAELEGALQKAKQDMACLLKEYQEVMNSKLALDIEIATYRRLLEGEEQRLCEGVGSVNVCVSSSRGGVTCGGLTYGTTPGRQIVSGPSVTGGSITVMAPDSCSPCQPRASSFTCGSSRSVRFA", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8M9PYS6-1", "uniprot_id": "A0A8M9PYS6_DANRE", "id": "A0A8M9PYS6-1", "name": "", "aln": "MSLSISMASSRMSGGYGGFGAGGGARLGLGLGGGASLGRGLGLGGGLGYGAGGGFG-LGLGGGAGAGAGLALGGGGGGALVASPAFAMGRAVAAG----GVGGSSAFAAGPATAAVAP--ILSRAAEKHTLSGLNDRFSTYMAKVRALQQENAALEAKLSQLTGGADVSPESSVAATVEYEAQLSEYRSTLETLTIDTVKLEIELDNVRGTAHELKAKLDFEQGVKFQLESDIAAMKKDIELASDLRIDLDAKYSSLKDELDYVSKTQEQELSSLQSKLGTSTMDTSVSMIEVDTGKSFDIATALNKMRMEYEKTVQQNREEAEAYYKLKMDEMQTVTAKNTEAVSLTKAEITSARKELQTLSLELQGLAAASMSLEQSLAEAQAQSSVGVAEYQAQIASLTSAIEVAKADLHKQILAYQELLDIKLALDVEISTYRKLLEGDDFKMPEFTETSYTFSGRALPHTSTPQDSPHSPAPKDTQTRYILTAGQIKVKEIITETSVISDADDTESS--------", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :* * *:* * * ... *. . . * * . **. .* . . .*. :*:** .*: * .: * . ... . . . * . : * : **. :. **.:*:::: *** *:*:* **:* . . ..: : . :. * * : *: :* **::*: . . * * : * .:: *.::..:***:: * : **:*: .:* :* .:: : *:*: **:::. : ::::*..:.::: : ::: :*:....:.* ***::*: * :**::.. :: *:: ** **.. .: :* *: *::. . .** ::***: *....::: :.::*.* .*:: ** *: : ***::: **.**:**:***:****:: :: * . : . . : .: : :.. :: : .*.*.* : :. . :.. .. ", "identical_positions": 109, "similar_positions": 192, "identity": "20.96%" }, { "cls_id": "homologset.agr.MGI:1859270", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O54922-1", "uniprot_id": "EXOC7_RAT", "id": "O54922-1", "name": "Exocyst complex component 7", "aln": "MIPPQEASARRREIEDKLKQEEETLSFIRDSLEKSDQLTKNMVSILSSFESRLMKLENSIIPVHKQTENLQRLQENVEKTLSCLDHVISYYHVASDTEKIIREGPTG-RLEEYLGSMAKIQKAVEYFQDNSPDSPELNKVKLLFERGKESLESEFRSLMTRHSKVISPVLVLDLISADDELEVQEDVVLEHLPESVLQDVIRISRWLVEYGRNQDFMNVYYQIRSSQLDRSIKGLKEHFRKSSSSSGVPYSPAIPNKRKDTPTKKPIKRP----------------------------------------------------------------------------------GRDDMLD--VETDAYIHCVSAFVRLAQSEYQLLMGIIPEHHQKKTFDSLIQDALDGLMLEGENIVSAARKAIIRHDFSTVLTVFPILRHLKQTKPEFDQVLQGTAASTKNKLPGLITSMETIGAKALEDFADNIKNDPDK----EYNMPKDGTVHELTSNAILFLQQLLDFQETAGAMLAS-------------QETSSSATSYNSEFSKRLLSTYICKVLGNLQLNLLSKSKVYEDPALSAIFLHNN-----------YNYILKSLEKSELIQLVAVTQKTAERSYREHIEQQIQTYQRSWLKVTDYIAEKNLPVFQPGVKLRDKERQMIKERFKGFNDGLEELCKIQKAWAIPDTEQRDKIRQAQKSIVKETYGAFLHRYSSVPFTKNPEKYIKYRVEQVGDMIDRLFDTSA", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9UPT5-3", "uniprot_id": "EXOC7_HUMAN", "id": "Q9UPT5-3", "name": "Exocyst complex component 7", "aln": "MIPPQEASARRREIEDKLKQEEETLSFIRDSLEKSDQLTKNMVSILSSFESRLMKLENSIIPVHKQTENLQRLQENVEKTLSCLDHVISYYHVASDTEKIIREGPTG-RLEEYLGSMAKIQKAVEYFQDNSPDSPELNKVKLLFERGKEALESEFRSLMTRHSKVVSPVLILDLISGDDDLEAQEDVTLEHLPESVLQDVIRISRWLVEYGRNQDFMNVYYQIRSSQLDRSIKGLKEHFHKSSSSSGVPYSPAIPNKRKDTPTKKPVKRPGTIRKAQNLLKQYSQHGLDGKKGGSNLIPLEGLLPCTPRGGLPGPWINAACVCAADISPGHEHDFRVKHLSEALNDKHGPLAGRDDMLD--VETDAYIHCVSAFVKLAQSEYQLLADIIPEHHQKKTFDSLIQDALDGLMLEGENIVSAARKAIVRHDFSTVLTVFPILRHLKQTKPEFDQVLQGTAASTKNKLPGLITSMETIGAKALEDFADNIKNDPDK----EYNMPKDGTVHELTSNAILFLQQLLDFQETAGAMLAS-------------QETSSSATSYSSEFSKRLLSTYICKVLGNLQLNLLSKSKVYEDPALSAIFLHNN-----------YNYILKSLEKSELIQLVAVTQKTAERSYREHIEQQIQTYQRSWLKVTDYIAEKNLPVFQPGVKLRDKERQIIKERFKGFNDGLEELCKIQKAWAIPDTEQRDRIRQAQKTIVKETYGAFLQKFGSVPFTKNPEKYIKYGVEQVGDMIDRLFDTSA", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "O35250-1", "uniprot_id": "EXOC7_MOUSE", "id": "O35250-1", "name": "Exocyst complex component 7", "aln": "MIPPQEASARRREIEDKLKQEEETLSFIRDSLEKSDQLTRNMVSILSSFESRLMKLENSIIPVHKQTENLQRLQENVEKTLSCLDHVISYYHVASDTEKIIREGPTG-RLEEYLGSMAKIQKAVEYFQDNSPDSPELNKVKLLFERGKESLESEFRSLMTRHSKVVSPVLLLDLISADDELEVQEDVVLEHLPESVLRDVVRISRWLVEYGRNQDFMNVYYQIRSSQLDRSIKGLKEHFRKSSSSSGVPYSPAIPNKRKDTPTKKPIKRPGTIRKAQNLLKQYSQHGLDGKKGGSNLIPLE---------------------------------------------------GRDDMLD--VETDAYIHCVSAFVKLAQSEYRLLMEIIPEHHQKKTFDSLIQDALDGLMLEGENIVSAARKAIIRHDFSTVLTVFPILRHLKQTKPEFDQVLQGTAASTKNKLPGLITSMETIGAKALEDFADNIKNDPDK----EYNMPKDGTVHELTSNAILFLQQLLDFQETAGAMLASQVLGDTYNIPLDPRETSSSATSYSSEFSKRLLSTYICKVLGNLQLNLLSKSKVYEDPALSAIFLHNN-----------YNYILKSLEKSELIQLVAVTQKTAERSYREHIEQQIQTYQRSWLKVTDYIAEKNLPVFQPGVKLRDKERQMIKERFKGFNDGLEELCKIQKVWAIPDTEQRDKIRQAQKDIVKETYGAFLHRYGSVPFTKNPEKYIKYRVEQVGDMIDRLFDTSA", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0AB32U114-1", "uniprot_id": "A0AB32U114_DANRE", "id": "A0AB32U114-1", "name": "Exocyst complex component 7", "aln": "MIPTEDASARKREIEEKLKQEQETLSFIRESLEKSDQLTKGMVSILSSFESRLMQLENSIIPVHKQTENLQRLQENVDKTLSNMDHVISYYHVAKDTDKIIREGPAG-RLYEYLACIAKIQKAVEYFQDNNPDSPELNTVKARFEKGKELLEAEFRSLLTRYSKPVPPVLILDAIGGDEDMEVQEEVTLEHLPEAVLQDIICISAWLVEYGRNQDFMNVYFQVRSSQLDRSIKGLKEHFRKNSATSAI-HSPAVQTKRKETPTKKAPKRPGTIRKAQNLLKQYSQHGLDGKKG-SNLTPLEG------------------------------FEHDLRGVKHLSDEKHGATAGKDDVLD--IEIDSYIHCISAFVKLAQSEYALLTEIIPEHHQKKTFDSLIQEALDNLMLEGDNIVSAARRAIMRHDYSAVLTIFPILRHLKQTKPDFDATLQGTAASTKNKLPALITSMETIGAKALEEFADSIKNDPDK----EYNMPKDGTVHELTSNAILFLQQLLDFQETAGAMLASQVLGDTYNIPLDPRESSSSASSYSSEFSRKLLSTYIYKVLGNLQLNLSNKAKVYEDPALRAIFLHNN-----------YNYILKSLEKSELIQLVAVTVKKVESSYRELIEQEIQNYQRSWLRVTEHLAERNIPDFQPGAKLKDKERQIIKDKFKGFNDGLEELCKIQKGWAVPDKEQRDTIRHAQKRVVSLTYKAFLQRCANISFTKNPEKYHRYSPEQVEDMIDRLFDTSA", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VSJ8-1", "uniprot_id": "EXOC7_DROME", "id": "Q9VSJ8-1", "name": "Exocyst complex component 7", "aln": "----MNNLDSSLQAHNKLEKEATNLALLKDRVDKYHDLSTQMSSILTIFEKRLGNLEQTILPVYQETEQLQKRQQNLEATLNCLESVLSHYDVSQEVCQLIHQGPVEGNISVFLDALAKLRDANDYFRHNNSQSVELENVTSLFNTGCEGLSQHYSMLLKKHSAPLKPVELLDLIYIEDD-SSDEYTSFRQLSQTTREELYTISHWLEQNLR--EYTNIYATERGEVVLRSLQLLKDHQ-KSNSWGHEALRPRHSGRQTEPKKTTSARLQQIFEKKANKLYLRATQTIEQSTGFSIKKASS----------------------------------------------HSDHLTSEDLMDGDQELDKYLVMLLGLQRLLNWERAIMIDIIPQSKHNEVFATLAYNAIDLVVKDAEAITQRILRCISRKEWTSALGIFSALKRVILLQPDIDRTYD---PAQREQLKKVLKKLQHTGAKALEHFLDVVKGESSTNIVGQSNVPKDATVHELTSNTIWFIEHLYDHFDVIGSILAQDVLYS-----TQLDTILMKKALPVEERNKALLAIYIKKALAELNLSIMNKCEQYNDQATKHLFRLNN-----------IHYILKSLQRSNLIDLVTLAEPECEHSYMEMIRELKASYQKTWSKMLVGIYSLDELPKPVAGKVKDKDRSVLKERFSNFNKDFEEACKIQRGISIPDVILREGIKRDNVEHILPIYNRFYEIYSGVHFSKNPDKYVKYRQHEINAMLSKLFDDSA", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P19658-1", "uniprot_id": "EXO70_YEAST", "id": "P19658-1", "name": "Exocyst complex component EXO70", "aln": "-------------MPAEIDIDEADVLVLSQELQKTSKLTFEINKSLKKIAATSNQSSQLFTPILARNNVLTTLQRNIESTLNSVASVKDLANEASKYEIILQKGINQVGLKQYTQVVHKLDDMLEDIQSGQANREENSEFHGILTHLEQLIKRSEAQLRVYFISILN-----SIKPFDPQINITKKMPFPYYEDQQLGALSWILDYFHGNSEGSIIQDILVGERSKLILKCMAFLEPFAKEISTAKNAPYEKGSSGMN--------------------------------------------------------------------------------------------------------------SYTEALLGFIANEKSLVDDLYSQYTESK--PHVLSQILSPLISAYAKLFGANLKIVRSNLENFGFFSFELVESIN----DVKKSLRGKELQNYNLLQDCTQEVRQVTQSLFRDAIDRIIKKANS----ISTIPSNNGVTEATVDTMSRLRKFSEYKNGCLGAMDNITRENWLPSNYKEKEYTLQNEALNWEDHNVLLSCFISDCIDTLAVNLERKAQIALMPNQEPDVANPNSSKNKHKQRIGFFILMNLTLVEQIVEKSELNLMLAGEGHSRLERLKKRYISYMVSDWRDLTANLMDSVFIDSSGKKSKDKEQIKEKFRKFNEGFEDLVSKTKQYKLSDPSLKVTLKSEIISLVMPMYERFYSRYKDS--FKNPRKHIKYTPDELTTVLNQLVR---", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ::. : : .: : ::* .*: : . *. : : .: : *: ..: * *.*:: **. : * . . :.. ::::* : : : *: . : :: ...: * . . : : :. * . : . : : . : : : : * :: . :: *.. : :.: *: . : .: . .: : * :: : .: ..: : : :. :: : : : : . : * :. : :.. : * .:. . :.. * : .... .:*.: * * * ::: :.:: :. : . : . . * . **: :* . : * :.: *.: . * ::: .:::: : .: . . . . . :.*::. :*::* **..:*: . : :.* : :: : * * . *** *: :* .:: ::.:*. ", "identical_positions": 47, "similar_positions": 201, "identity": "6.14%" }, { "cls_id": "homologset.agr.MGI:1859271", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9Z2G9-1", "uniprot_id": "HTAI2_MOUSE", "id": "Q9Z2G9-1", "name": "Protein HTATIP2", "aln": "MADKEALPKLREDFKMQNKSVFILGASGETGKVLLKEILGQNLFSKVTLIGRRKLTFEEEAYKNVNQEVVDFEKLDVYASAFQGHDVGFCCLGTTRSKAG-AEGFVRVDRDYVLKSAELAKAGGCKHFNLLSSRGADKSSSFLYLQVKGEVEAKVEELKFDRLSVFRPGVLLCDRQESRP-----------GEWLARKFFGSLPDSWASGYAVPVVTVVRAMLNNLVSPSSGQMELLENKAILHLGKDRDVPKL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "B0BNF8-1", "uniprot_id": "HTAI2_RAT", "id": "B0BNF8-1", "name": "Protein HTATIP2", "aln": "MADKETLLKLREDFKMQNKSVFILGASGETGKVLLKEILGQNLFSKVTLIGRRKLTFEEEAYNNVNQEVVDFEKLDEYAPAFQGHDVGFCCLGTTRRKAG-ADGFVRVDRDYVLKSAELAKAGGCKHFNLLSSRGADKSSSFLYLQVKGEVEAKVEELKFDRLSVFRPGVLLCDRQESRP-----------GEWLARKFFGSLPDSWASGYAVPVVTVVRAMLNNLVSPGSGQMELLENKAILHLGKDSDGPKL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9BUP3-1", "uniprot_id": "HTAI2_HUMAN", "id": "Q9BUP3-1", "name": "Protein HTATIP2", "aln": "MAETEALSKLREDFRMQNKSVFILGASGETGRVLLKEILEQGLFSKVTLIGRRKLTFDEEAYKNVNQEVVDFEKLDDYASAFQGHDVGFCCLGTTRGKAG-AEGFVRVDRDYVLKSAELAKAGGCKHFNLLSSKGADKSSNFLYLQVKGEVEAKVEELKFDRYSVFRPGVLLCDRQESRP-----------GEWLVRKFFGSLPDSWASGHSVPVVTVVRAMLNNVVRPRDKQMELLENKAIHDLGKAHGSLKP", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P40008-1", "uniprot_id": "FMP52_YEAST", "id": "P40008-1", "name": "Protein FMP52, mitochondrial", "aln": "---------------MNG---LVLGATGLCGGGFLRHAQEAPQFSKVYAILRRELPFPATD-KVVAIVERDNSKWSQLITNEMNPQVLFTALATTRAAAGGLDKQYKIDHDLNLQLAQAAKEKGCETIVLVSSAGAHPDSRFGYMKMKGEIERDVIALDFKHIIILRPGPLLGERTNSKQSGFGGNLTAALGTRVYRSRFQRLLGYPVYGDEVGKVGVHLALN----TSGKDKVQFVSSKDILDISASLEKIAT", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *:. ::***:* * :*:. **** * **:*.* : * * .* . . . :* * .*.*** ** : ::*:* *: *: ** **: : *:** **. .* * *:::***:* .* *.*.: ::*** ** :* :*: * : *. * * . . * * * * *: . . :::::..* * .:. ", "identical_positions": 68, "similar_positions": 59, "identity": "26.77%" }, { "cls_id": "homologset.agr.MGI:1859274", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q53GG5-1", "uniprot_id": "PDLI3_HUMAN", "id": "Q53GG5-1", "name": "PDZ and LIM domain protein 3", "aln": "MPQTVILPGPAP--------------------------------------WGFRLSGGIDFNQPLVITRITPGSKAAAANLCPGDVILAIDGFGTESMTHADAQDRIKAAAHQLCLKIDRGE-----------------THLWSPQVSEDG--KAHPFKINLESEPQDGNYFEHKHNIRPKPFVIPGRSSGCSTPSGIDCGSGRSTPSSVSTVSTICPGDLKVAAKLAPNIPLEMELPGVKIVHAQFNTPMQLYSDDNIMETLQG-QVSTALGETPLMSEPTASVPPESDVYRMLHDNRNEPTQPRQSGSFRVLQGMVDDGSDDRPAGTRSVRAPVTKVHGGSGGAQRMPLCDKCGSGIVGAVVKARDKYRHPECFVCADCN--------------------------------LNLKQKGYFFIEGELYCETHARARTKPPEGYDTVTLYPKA-------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q66HS7-1", "uniprot_id": "PDLI3_RAT", "id": "Q66HS7-1", "name": "PDZ and LIM domain protein 3", "aln": "MPQNVVLPGPAP--------------------------------------WGFRLSGGIDFNQPLVITRITPGSKAEAANLCPGDVILAIDGFGTESMTHADAQDRIKAASYQLCLKIDRAE-----------------TRLC-PAVSEDG--KAHPFKINLEAEPQDVNYFEHKHNIRPKPFIIPGRTSGCSTPSGIDCGSGRSTPSSVSTVSTICPGDLKVAAKMAPNIPLEMELPGVKIVHAQFNTPMQLYSDDNIMETLQG-QVSTALGETPSMSEPTASVPPQSDVYRMLHDNRDEPAAPRQSGSFRVLQELVNDGSDDRPAGTRSVR-PVTKVHGGAGGAQRMPLCDKCGSGIVGAVVKARDKYRHPECFVCADCN--------------------------------LNLKQKGYFFVEGELYCEMHARARTRPPEGYDTVTLYPKA-------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O70209-1", "uniprot_id": "PDLI3_MOUSE", "id": "O70209-1", "name": "PDZ and LIM domain protein 3", "aln": "MPQNVVLPGPAP--------------------------------------WGFRLSGGIDFNQPLVITRITPGSKAAAANLCPGDVILAIDGFGTESMTHADAQDRIKAASYQLCLKIDRAE-----------------TRLWSPQVSEDG--KAHPFKINLEAEPQEFKPIGTAHNRRAQPFVAAAN---------IDDKR--------------------------------------QVVSASYNSPIGLYSTSNIQDALHG-QLRGLIPGS-LQNEPTASVPPQSDVYRMLHDNRDDPAAPRQSGSFRVLQDLVNDGPDDRPAGTRSVRAPVTKVHGGAGSAQRMPLCDKCGSGIVGAVVKARDKYRHPECFVCADCN--------------------------------LNLKQKGYFFVEGELYCETHARARTRPPEGYDTVTLYPKA-------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8M2B416-1", "uniprot_id": "A0A8M2B416_DANRE", "id": "A0A8M2B416-1", "name": "PDZ and LIM domain protein 3", "aln": "MPQNVVLDGPAP--------------------------------------WGFRLSGGKDFNQPLTITRVTPGSKASRVNLCPGDIILSIQGVSTDGMTHAEAQNNIKDSTNQLFLKIERPE-----------------TKIWSPQVIEEG--KVNPFKINLEAEKQDIDYFEHKFNVRPKPFTSASQRSDSTSQTLMGNVAQMAGTPS-------------------------------TAHSVQYNSPIALYSADNVSNTLQQAQMSTVVRQASPSSKPLTSIED-SHVYRMLQDANEQPHEPRQSGSFKALQDYVES-DGTRPMVTRSVKAPVTKPQAATSSLQKLPLCDKCGTGIVGTVVKARDKYRHPACFVCSDCG--------------------------------MNLKQKGYFFVDGQMYCEAHARMRMTPPEGHDLVTVYPTA-------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "B7YZE5-1", "uniprot_id": "B7YZE5_DROME", "id": "B7YZE5-1", "name": "PDZ domain-containing protein", "aln": "MPEQLGLLWSVPESKSKAPIIKVSCGIGDTDGYPAFDVDSDAYATKDDSRWGFLITGGAEFHMPLTVFQVTPNGLADKAGIRLGDIILEINEEDASQLTLSQAHEKINSTPKKIHFLLRNMEEDDPMGQFEAGEEKSIVMRVPKPLPPPSGRIRASSIEMRLLEMQRKLSAIAEIPKILCSTLATVSQNFGRMSESEVDEDDVGEEEAYVQRKFSYDEDALDFELRNGEQAG--------DTDSDEEDLVLVREEDAEDVDVPKGAKQSKLLKDVTPESDYASEANYPANEASDDTESDDE-DEPGSTVYFMKLPAAAAEDTYSSTEDEDDSDFLNTTYTWNLRNVPKLRINDAEAEGELTLGHQAREVPQQEQPQEKQPCLEPEPPKVRPATPTPKAPPQESAEGQTQKLLFRLDKLERSWPWADREKIIYKQSTCHLVPRKPLGLVGQRMQLLLKDKKE", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "**: : * ..* *** ::** :*: **.: ::**.. * ..: **:** *: .:. :* ::*::.*: :. :: : : . * :: * .* :. .:::.* :. . : : ..: .. :. . : : . : :. : : : .. :. :. : :: * .: * * . . . . *. . :: : * . * : :**: :: * :: ::.: : : : :: : * : . * ", "identical_positions": 38, "similar_positions": 108, "identity": "8.24%" }, { "cls_id": "homologset.agr.MGI:1859281", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9R098-1", "uniprot_id": "HGFA_MOUSE", "id": "Q9R098-1", "name": "Hepatocyte growth factor activator serine protease", "aln": "--------------------------------------MGRQAWISSLCPLPRPCPF-LLLLLLLVVPRGAQPQAGRNHTEPPGPNVTATPVTPTIPVISGNVSTSTESAP--AAETEGPQSERYPPPS----SSSPPGGQVLTESGQPCRFPFRYGGRMLHSCTSEGSAYRKWCATTHNYDRDRAWGYCAEVTLPVEGPAILDPCASGPCLNGGTCSSTHDHGSYHCSCPLAFTGKDCGTEKCFDETRYEYFEVGDHWARVSEGHVEQCGCMEGQARCEDTHHTACLSSPCLNGGTCHLIVGTGTSVCTCPLGYAGRFCNIVPTEHCFLGNGTEYRGVASTAASGLSCLAWNSDLLYQELHVDSVAAAVLLGLGPHAYCRNPDKDERPWCYVVKDNALSWEYCRLTACESLARVHSQTPEILAALPESAPAVRPTCGKRHKKRTFLRPRIIGGSSSLPGSHPWLAAIYIGNSFCAGSLVHTCWVVSAAHCFANSPPRDSITVVLGQHFFNRTTDVTQTFGIEKYVPYTLYSVFNPNNHDLVLIRLKKKGERCAVRSQFVQPICLPEAGSSFPTGHKCQIAGWGHMDENVSSYSNSLLEALVPLVADHKCSSPEVYGADISPNMLCAGYFDCKSDACQGDSGGPLVCEKNGVAYLYGIISWGDGCGRLNKPGVYTRVANYVDWINDRIRPPKRPVATS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "F7ELL4-1", "uniprot_id": "F7ELL4_RAT", "id": "F7ELL4-1", "name": "Hepatocyte growth factor activator serine protease", "aln": "MHGGGRVNHYRVALTPPALATFPGLSAPATPHASSGGAMRQRAWLPSVS--SRPCPF-LLLLLLLVVPRVAQPQAGRNHTEPPGPNVTATRMTPMIPATSGNFSTSIGSDPEGEAETEGPQSERYLLSS----SSSPLGGQVLTESGQPCRFPFRYGGRMLHSCSSEGSAYRKWCATTHNYDRDRAWGYCAEATLPVEGPAVLDPCASGPCLNGGTCSSTQDHVSYHCACPLAFTGKDCGTEKCFDETRYEYFEVGDHWARVSEGHVEQCSCIEGQARCEDTHHTACLSSPCLNGGTCHLIVGTGTSICACPLGYAGRFCNIVPTERCFLGNGTEYRGVASTSASGLSCLAWNSDLLYQELHVDSVGAAALLGLGPHAYCRNPDKDERPWCYVVKDSALSWEYCRLAACESLARVHSRIPEVLATLPESTSTARPTCGKRHKKRTFLRPRIIGGSSSLPGSHPWLAAIYIGNGFCAGSLVHTCWVVSAAHCFSSSPPRDSITVVLGQHFFNRTTDVTQTFAIEKYVPYTLYSVFNPNDHDLVLIRLKKKGERCAVRSQFVQPICLPEAGSSFPTGHKCQIAGWGHMDENVSGYSNSLLEALVPLVADHKCSSPEVYGADISPNMLCAGYFDCKSDACQGDSGGPLVCEKNGVAYLYGIISWGDGCGRLNKPGVYTRVSNYVDWINDRIRPPKRPAAAS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q04756-1", "uniprot_id": "HGFA_HUMAN", "id": "Q04756-1", "name": "Hepatocyte growth factor activator serine protease", "aln": "--------------------------------------MGRWAWVPSPWPPPGLGPFLLLLLLLLLLPRGFQPQPGGNRTESPEPNATATPAIPTILVTSVTSETPATSAP----EAEGPQSGGLPPPPRAVPSSSSPQAQALTEDGRPCRFPFRYGGRMLHACTSEGSAHRKWCATTHNYDRDRAWGYCVEATPPPGGPAALDPCASGPCLNGGSCSNTQDPQSYHCSCPRAFTGKDCGTEKCFDETRYEYLEGGDRWARVRQGHVEQCECFGGRTWCEGTRHTACLSSPCLNGGTCHLIVATGTTVCACPPGFAGRLCNIEPDERCFLGNGTGYRGVASTSASGLSCLAWNSDLLYQELHVDSVGAAALLGLGPHAYCRNPDNDERPWCYVVKDSALSWEYCRLEACESLTRVQ-LSPDLLATLPEPASPGRQACGRRHKKRTFLRPRIIGGSSSLPGSHPWLAAIYIGDSFCAGSLVHTCWVVSAAHCFSHSPPRDSVSVVLGQHFFNRTTDVTQTFGIEKYIPYTLYSVFNPSDHDLVLIRLKKKGDRCATRSQFVQPICLPEPGSTFPAGHKCQIAGWGHLDENVSGYSSSLREALVPLVADHKCSSPEVYGADISPNMLCAGYFDCKSDACQGDSGGPLACEKNGVAYLYGIISWGDGCGRLHKPGVYTRVANYVDWINDRIRPPRRLVAPS", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * : **:.* . ** *******::** ***.* *:**.* **.*** * * . * . .*. * * *:***** .. ***. .*.***.*:**************:*:*****:*******************.*.* * *** *************:**.*:* ****:** ********************:* **:**** :****** *: *:: **.*:*******************.***::*:** *:***:*** * *:******* *******:***********************.**.**************:***********.********* *****:**: *::**:***.:.. * :**:********************************:.*******************: ******::******************.****:**********.:************:***.************.**:**:***********:*****.**.** ***********************************************.**********************:********:*************:* .*.*", "identical_positions": 510, "similar_positions": 85, "identity": "73.07%" }, { "cls_id": "homologset.agr.MGI:1859284", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "B4F7F0-1", "uniprot_id": "B4F7F0_RAT", "id": "B4F7F0-1", "name": "Claudin", "aln": "MASTGLQILGIVLTLLGWVNALVSCALPMWKVTAFIGNSIVVAQMVWEGLWMSCVVQSTGQMQCKVYDSLLALPQDLQAARALCVITLLIVLLGLLLYLAGAKCTTCVEDKNSKSRLVLISGVIFVISGVLTLIPICWTAHAIIQDFYNPLVADAQKRELGASLYLGWAASGLLLIGGGLLCCACSSGGTQGPSHYVARYSSPVP-HSRGPSEYPSKNYV", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9Z262-1", "uniprot_id": "CLD6_MOUSE", "id": "Q9Z262-1", "name": "Claudin-6", "aln": "MASTGLQILGIVLTLLGWVNALVSCALPMWKVTAFIGNSIVVAQMVWEGLWMSCVVQSTGQMQCKVYDSLLALPQDLQAARALCVVTLLIVLLGLLVYLAGAKCTTCVEDRNSKSRLVLISGIIFVISGVLTLIPVCWTAHSIIQDFYNPLVADAQKRELGASLYLGWAASGLLLLGGGLLCCACSSGGTQGPRHYMACYSTSVP-HSRGPSEYPTKNYV", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P56747-1", "uniprot_id": "CLD6_HUMAN", "id": "P56747-1", "name": "Claudin-6", "aln": "MASAGMQILGVVLTLLGWVNGLVSCALPMWKVTAFIGNSIVVAQVVWEGLWMSCVVQSTGQMQCKVYDSLLALPQDLQAARALCVIALLVALFGLLVYLAGAKCTTCVEEKDSKARLVLTSGIVFVISGVLTLIPVCWTAHAIIRDFYNPLVAEAQKRELGASLYLGWAASGLLLLGGGLLCCTCPSGGSQGPSHYMARYSTSAPAISRGPSEYPTKNYV", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "***:*:****:*********.***********************:****************************************::**:.*:***:************:::**:**** **::***********:*****:**:********:*********************:*******:*.***:*** **:* **:..* ********:****", "identical_positions": 185, "similar_positions": 30, "identity": "84.09%" }, { "cls_id": "homologset.agr.MGI:1859285", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9Z1L1-1", "uniprot_id": "CLD7_RAT", "id": "Q9Z1L1-1", "name": "Claudin-7", "aln": "MANSGLQLLGFSMAMLGWVGLIASTAIPQWQMSSYAGDNIITAQAMYKGLWMECVTQSTGMMSCKMYDSVLALPAATQATRALMIVSLVLGFLAMFVATMGMKCTRCGGDDKVKKARIAMTGGIIFIVAGLAALVACSWIGHQIVTDFYNPLTPMNIKYEFGPAIFIGWAGSALVLLGGALLSCSCPGSESKAAY-RAPRSYPKSN---SSKEYV", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9Z261-1", "uniprot_id": "CLD7_MOUSE", "id": "Q9Z261-1", "name": "Claudin-7", "aln": "MANSGLQLLGFSMAMLGWVGLIASTAIPQWQMSSYAGDNIITAQAMYKGLWMECVTQSTGMMSCKMYDSVLALPGALQATRALMVVSLVLGFLAMFVATMGMKCTRCGGDDKAKKARIAMTGGIVFIVAGLAALVACSWIGHQIVTDFYNPLTPMNVKYEFGPAIFIGWAGSALVLLGGALLSCSCPGSESKAAY-RAPRSYPKSN---SSKEYV", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O95471-1", "uniprot_id": "CLD7_HUMAN", "id": "O95471-1", "name": "Claudin-7", "aln": "MANSGLQLLGFSMALLGWVGLVACTAIPQWQMSSYAGDNIITAQAMYKGLWMDCVTQSTGMMSCKMYDSVLALSAALQATRALMVVSLVLGFLAMFVATMGMKCTRCGGDDKVKKARIAMGGGIIFIVAGLAALVACSWYGHQIVTDFYNPLIPTNIKYEFGPAIFIGWAGSALVILGGALLSCSCPGNESKAGY-RVPRSYPKSN---SSKEYV", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9YH92-1", "uniprot_id": "CLD7B_DANRE", "id": "Q9YH92-1", "name": "Claudin-7-B", "aln": "MAHKGLQLLGFTLSLLGLIGLIIGTIMPQWKMSAYVGDNIITAIAMYQGLWMSCAYQSTGQQQCKVYDSVLQLDSALQATRALMVVAILLTVAGLGVASMGMKCTNCGGDDKVKKSRIAMTGGIILSVGALCSIVACGWFTSQIIRDFYNPFTPVNTKYEFGAAIFIAWAGAFLDIMGGGMLASSCSKGQSSPNYPKSSRPVKSSRPPSSSKEYV", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q6DHP1-1", "uniprot_id": "CLD7A_DANRE", "id": "Q6DHP1-1", "name": "Claudin-7-A", "aln": "MANSGVQLLGFGLSLIGIIGLIVGTILPQWKMSAYVGDSIITAVATYQGLWMSCAFQSTGQLQCKIYDSILQLDSDLQATRALMIVGIIVSIAGLGVASIGMKCTTCGADDKVRKTRTAMTGGIILLVGALCAVVACSWFAHNVIRAFYNPFTPVNTKFEFGAAIFIAWGGSFLDVLGGAMLAASCPRSKQVSKYPKSN-STRSAN--GSNKEYV", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "**:.*:***** ::::* :**: * :***:**:*.**.**** * *:****.*. **** .**:***:* * . *******:*.::: . .: **::***** **.***.:*:* ** ***:: *..*.::***.* ::: ****: * * *:***.****.*.*: * ::**.:*:.**. .:. . * : . .:. *.****", "identical_positions": 103, "similar_positions": 69, "identity": "47.91%" }, { "cls_id": "homologset.agr.MGI:1859286", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9Z260-1", "uniprot_id": "CLD8_MOUSE", "id": "Q9Z260-1", "name": "Claudin-8", "aln": "MATYALQMAALVLGGVGMVGTVAVTIMPQWRVSAFIESNIVVFENRWEGLWMNCMRHANIRMQCKVYDSLLALSPDLQASRGLMCAASVLAFLAFMTAILGMKCTRCTGDDENVKSRILLTAGIIFFITGLVVLIPVSWVANSIIRDFYNPLVDVALKRELGEALYIGWTTALVLIAGGALFCCVFCCTERSNSYRYSVPSHRTTQRSFHAEKRSPSIYSKSQYV", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P56748-1", "uniprot_id": "CLD8_HUMAN", "id": "P56748-1", "name": "Claudin-8", "aln": "MATHALEIAGLFLGGVGMVGTVAVTVMPQWRVSAFIENNIVVFENFWEGLWMNCVRQANIRMQCKIYDSLLALSPDLQAARGLMCAASVMSFLAFMMAILGMKCTRCTGDNEKVKAHILLTAGIIFIITGMVVLIPVSWVANAIIRDFYNSIVNVAQKRELGEALYLGWTTALVLIVGGALFCCVFCCNEKSSSYRYSIPSHRTTQKSYHTGKKSPSVYSRSQYV", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "***:**::*.*.*************:***********.******* ********:*:********:*************:*********::***** *************:*:**::*********:***:***********:*******.:*:** *********:*********.***********.*:*.*****:*******:*:*: *:***:**:****", "identical_positions": 186, "similar_positions": 35, "identity": "82.67%" }, { "cls_id": "homologset.agr.MGI:1859287", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q1LZ50-1", "uniprot_id": "DNM3L_RAT", "id": "Q1LZ50-1", "name": "DNA (cytosine-5)-methyltransferase 3-like", "aln": "MGSRETPSSCSKTHETLNLETPESSSTDPDSPLEEQWPKSAPDLKEEDSMDMVLEDSKEPLTPSSPPTGREVIRYEVNVNQRNIEDICLCCGSLQVYAQHPLFEGGICAPCKDKFLETLFLYDEDGHQSYCTICCSGHTLFICESPDCTRCYCFECVDILVGPGTSERINAMACWVCFLCLPFSRSGLLQRRKKWRHQLKAFHDREGASPVEIYKTVSAWKRQPVRVLSLFGNIDKELKSLGFLESSSGSEGGTLKYVEDVTNVVRREVEKWGPFDLVYGSTQPLGYSCDRCPGWYMFQFHRILQYARPRQDSQQPFFWIFVDNLLLTEDDQETTVRFLQTEAVTLQDVRGRVLQNAMRVWSNIPGLKSKHADLTPKEEQSLQTQVRTRSKLAAQKVDSLVKYCLLPLREYFKYFSQNSLPL-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9CWR8-1", "uniprot_id": "DNM3L_MOUSE", "id": "Q9CWR8-1", "name": "DNA (cytosine-5)-methyltransferase 3-like", "aln": "MGSRETPSSCSKTLETLDLETSDSSSPDADSPLEEQWLKSSPALKE-DSVDVVLEDCKEPLSPSSPPTGREMIRYEVKVNRRSIEDICLCCGTLQVYTRHPLFEGGLCAPCKDKFLESLFLYDDDGHQSYCTICCSGGTLFICESPDCTRCYCFECVDILVGPGTSERINAMACWVCFLCLPFSRSGLLQRRKRWRHQLKAFHDQEGAGPMEIYKTVSAWKRQPVRVLSLFRNIDKVLKSLGFLESGSGSGGGTLKYVEDVTNVVRRDVEKWGPFDLVYGSTQPLGSSCDRCPGWYMFQFHRILQYALPRQESQRPFFWIFMDNLLLTEDDQETTTRFLQTEAVTLQDVRGRDYQNAMRVWSNIPGLKSKHAPLTPKEEEYLQAQVRSRSKLDAPKVDLLVKNCLLPLREYFKYFSQNSLPL-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9UJW3-1", "uniprot_id": "DNM3L_HUMAN", "id": "Q9UJW3-1", "name": "DNA (cytosine-5)-methyltransferase 3-like", "aln": "------------------MAAIPALDPEAEP-----------------SMDVILVGSSELSSSVSPGTGRDLIAYEVKANQRNIEDICICCGSLQVHTQHPLFEGGICAPCKDKFLDALFLYDDDGYQSYCSICCSGETLLICGNPDCTRCYCFECVDSLVGPGTSGKVHAMSNWVCYLCLPSSRSGLLQRRRKWRSQLKAFYDRESENPLEMFETVPVWRRQPVRVLSLFEDIKKELTSLGFLES--GSDPGQLKHVVDVTDTVRKDVEEWGPFDLVYGATPPLGHTCDRPPSWYLFQFHRLLQYARPKPGSPRPFFWMFVDNLVLNKEDLDVASRFLEMEPVTIPDVHGGSLQNAVRVWSNIPAIRSRHWALVSEEELSLLAQNKQSSKLAAKWPTKLVKNCFLPLREYFKYFSTELTSSL", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : : ..:.:. *:*::* ...* :. ** ***::* ***:.*:*.*****:***:***:::*******:*********::*****:**:****:***** **:** .************* ******* :::**: ***:**** *********::** *****:*:*. .*:*:::**..*:********** :*.* *.******* ** * **:* ***:.**::**:*********:* *** :*** *.**:*****:**** *: * :****:*:***:*.::* :.: ***: *.**: **:* ***:*******.::*:* *..:** * :* : *** * *** *:*********** : . ", "identical_positions": 232, "similar_positions": 96, "identity": "54.85%" }, { "cls_id": "homologset.agr.MGI:1859288", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P63156-1", "uniprot_id": "BARH1_RAT", "id": "P63156-1", "name": "BarH-like 1 homeobox protein", "aln": "-------------------------------------------------------------------MEGSNGFGIDSILSHRAGSPALPKGDPLLGDCRSPLELSPRSESSSD----------------------------------------------CSSPASPGRDCLETSTS-----------------------------------------------------------------------------------------RPGAASGPGLDSHLQPGQLSAPAQSRTVTSSFLIRDILADCKPLAACAPYSSSGQPAAPEPGGRLAAKAGEDFRDKLDKSVSSASSDSEYKVKEEGDREISSSRDSPPVRLKKPRKARTAFTDHQLAQLERSFERQKYLSVQDRMELAASLNLTDTQVKTWYQNRRTKWKRQTAVGLELLAEAGNYSALQRMFPSP------YFYPQSLVSN----LDPGAALYLYRGPSAPPPALQRPLVPRILIHGLQGASE---------------PPPPLPPLPGVLPRAAQPR--------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P63157-1", "uniprot_id": "BARH1_MOUSE", "id": "P63157-1", "name": "BarH-like 1 homeobox protein", "aln": "-------------------------------------------------------------------MEGSNGFGIDSILSHRAGSPALPKGDPLLGDCRSPLELSPRSESSSD----------------------------------------------CSSPASPGRDCLETSTS-----------------------------------------------------------------------------------------RPGAASGPGLDSHLQPGQLSAPAQSRTVTSSFLIRDILADCKPLAACAPYSSSGQPAAPEPGGRLAAKAGEDFRDKLDKSVSSASSDSEYKVKEEGDREISSSRDSPPVRLKKPRKARTAFTDHQLAQLERSFERQKYLSVQDRMELAASLNLTDTQVKTWYQNRRTKWKRQTAVGLELLAEAGNYSALQRMFPSP------YFYPQSLVSN----LDPGAALYLYRGPSAPPPALQRPLVPRILIHGLQGASE---------------PPPPLPPLPGVLPRAAQPR--------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9BZE3-1", "uniprot_id": "BARH1_HUMAN", "id": "Q9BZE3-1", "name": "BarH-like 1 homeobox protein", "aln": "-------------------------------------------------------------------MEGSNGFGIDSILSHRAGSPALPKGDPLLGDCRSPLELSPRSESSSD----------------------------------------------CSSPASPGRDCLETGTP-----------------------------------------------------------------------------------------RPGGASGPGLDSHLQPGQLSAPAQSRTVTSSFLIRDILADCKPLAACAPYSSSGQPAAPEPGGRLAAKAAEDFRDKLDKSGSNASSDSEYKVKEEGDREISSSRDSPPVRLKKPRKARTAFTDHQLAQLERSFERQKYLSVQDRMELAASLNLTDTQVKTWYQNRRTKWKRQTAVGLELLAEAGNYSALQRMFPSP------YFYPQSLVSN----LDPGAALYLYRGPSAPPPALQRPLVPRILIHGLQGASE---------------PPPPLPPLAGVLPRAAQPR--------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q24256-1", "uniprot_id": "BARH2_DROME", "id": "Q24256-1", "name": "Homeobox protein B-H2", "aln": "MTTMPPEMSATTAAPVGSAPSATAHHPAAVGGGMPRPASPAVGSNTTTATATTATRSRFMITDILAGAAAASAAAAAAAAALAAASSGGGRGSPTDSEREQSLVAQHHHHHQQQQQHHHHQQQQQQQQHQQAALQQYIVQQQQLLRFEREREREREREHYRERHSPPGNNPYAHHPMPPHLLAHFPPAHYAVLQQQQQQQQQQQHPHPHHLQLERERLEALHRHGHGLTGDPAQHLSHLSHLSHQQHHPHLHHPMHDERSRSPLMLQQLGGNGGNNNNNNNNSSSASNNNNNNNNSASANSNIISGNSSSSNNNNGSGNGNMLLGGPGSSISGDQASTIDDSDSDDCGGKDDDGDDSMKNGSSANGDSSSHLSLSLSKKQRKARTAFTDHQLQTLEKSFERQKYLSVQDRMELANKLELSDCQVKTWYQNRRTKWKRQTAVGLELLAEAGNYAAFQRLYGGATPYLSAWPYAAAAAAQSPHGATP-SAIDIYYRQAAAAAAMQKPSLPASYRMYQSSIPPGMSLPGMPAPP----PPGAAPMLSGYY--AAAAAAAASAGAQQQQQQPPAASRSPATSQSANSEADCERTSSSSRQRLITPSPPLNPGSPPHRERINEEEDRERDEERDIERERERERERDEDDEEELALEV", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q24255-1", "uniprot_id": "BARH1_DROME", "id": "Q24255-1", "name": "Homeobox protein B-H1", "aln": "---MKDSMSILTQTPS-----------------EPNAAHPQLHHHLS--TLQQQHHQHHLHYGLQPPAVAHSIHSTTTMSSGGSTTTASGIGKPNRSRFMINDILAGSAAAAFYKQQQHHQQLHHHNNNNNSGSSG-----------------GSSPAHSNNNNNINGDNCEASNVAGVGVLP-------SALHHPQPHPPTHPHTHPHALMHPHGKLGHFPPTAGGNGLNVAQYAAAM-----QQHY------------------AAAAAAAAARNNAAAAAAAAAAAAAAGVAAPPVDGGVDGGVGLAPPAGGDLDDSSDYHEENEDCDSGN----MDDHSVCSNGGKDDDGN-SVKSGSTS--DMSG-----LSKKQRKARTAFTDHQLQTLEKSFERQKYLSVQERQELAHKLDLSDCQVKTWYQNRRTKWKRQTAVGLELLAEAGNFAAFQRLYGGS-PYLGAWPYAAAAGAA--HGATPHTNIDIYYRQAAAAAAMQKP-LPYNLYAGVPSVGVGVGVGVGPAPFSHLSASSSLSSLSSYYQSAAAAASAANPGGPHPVAPPPSVGGGSPPSGLVKPIPAHSASASPPPRPPSTPSPTLNPGSPPGRS---------------------VDSCSQSDDEDQIQV--", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . . . : : : :.. *.* . . * : .. . :. . :: :. .: .. . .... . :.. : * . .. ..*.: .:*. . . * ** ************ **:***********:* *** .*:*:* *****************************::*:**:: .. : *. : : * : : :* :*...*:*:* :* . .. . . *.. ** . ", "identical_positions": 84, "similar_positions": 83, "identity": "12.88%" }, { "cls_id": "homologset.agr.MGI:1859293", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9ER24-1", "uniprot_id": "ATX10_RAT", "id": "Q9ER24-1", "name": "Ataxin-10", "aln": "--MAAPRMPPSRLSGIMVPAP------------IQDLEALRALTALFKEQRNRETAPRTIFQRVLDILKKSTQAVELACRDPSQVEHLASSLQLITECFRCLRN--------------ACIECSVNQNSIRNLDTIGVAVDLVLLFRELRVEQDSLLTAFRCGLQFLGNVASRNEDS---------------QSIVWVHAFPELFMSCLNHPDKKIVAYCSMILFTSLNSERMKDLEENLNIAINVIEAHQKHPESEWPFLIITDHFLKSPELVEAMYGKLSN--QER-----VTLLDIMIAKIVGDEQLTKDDISIFLRHAELIANSFVDQCRNVLKLTSE----PQTEDKEALVTIRLLDVLCEMTSNTELLGYLQVFPGLMERV-------IDVLRVIHSVGK-------DSTN-----IFSPSDSLKAEGDIEH-----MTEGFKSHLIRLIGNLCYKNKENQDKVNELDGIPLILDSSNIDDNNPFMMQWVVYAVRNLTEDNSQNQDFIAKMEEQGLADASLLKKMGFEVEK-SGDKLILKSNNDIPPP-----------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P28658-1", "uniprot_id": "ATX10_MOUSE", "id": "P28658-1", "name": "Ataxin-10", "aln": "--MAAPRMPPSRLSGIMVPAP------------IQDLEALRALTALFKEQRNRETAPRTIFQRVLDILKKSTHAVELACRDPSQVEHLASSLQLITECFRCLRN--------------ACIECSVNQNSIRNLDTIGVAVDLVLLFRELRVEQDSLLTAFRCGLQFLGNVASRNEES---------------QSIVWVHAFPELFMSCLNHPDKKIVAYCSMILFTSLNAERMKDLEENLNIAINVIEAHQKHPASEWPFLIISDHFLKSPELVEAMYGKLSN--QER-----ITLLDIVIAKLVGEEQLTKDDISIFVRHAELIANSFMDQCRNVLKLTSE----PHTEDKEALVTIRLLDVLCEMTSNTELLGYLQVFPGLMERV-------IDVLRVIHEVGK-------ESTN-----IFSPSDSLKAEGDIEH-----MTEGFKSHLIRLIGNLCYKNKENQDKVNELDGIPLILDSSNIDDNNPFMMQWVVYAVRNLTEDNSQNQDVIAKMEEQGLADASLLKKMGFEIEK-SGDKLILKSNNDIPPP-----------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9UBB4-1", "uniprot_id": "ATX10_HUMAN", "id": "Q9UBB4-1", "name": "Ataxin-10", "aln": "--MAAPRPPPARLSGVMVPAP------------IQDLEALRALTALFKEQRNRETAPRTIFQRVLDILKKSSHAVELACRDPSQVENLASSLQLITECFRCLRN--------------ACIECSVNQNSIRNLDTIGVAVDLILLFRELRVEQESLLTAFRCGLQFLGNIASRNEDS---------------QSIVWVHAFPELFLSCLNHPDKKIVAYSSMILFTSLNHERMKELEENLNIAIDVIDAYQKHPESEWPFLIITDLFLKSPELVQAMFPKLNN--QER-----VTLLDLMIAKITSDEPLTKDDIPVFLRHAELIASTFVDQCKTVLKLASE----EPPDDEEALATIRLLDVLCEMTVNTELLGYLQVFPGLLERV-------IDLLRVIHVAGK-------ETTN-----IFSNCGCVRAEGDISN-----VANGFKSHLIRLIGNLCYKNKDNQDKVNELDGIPLILDNCNISDSNPFLTQWVIYAIRNLTEDNSQNQDLIAKMEEQGLADASLLKKVGFEVEK-KGEKLILKSTRDTPKP-----------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "B7YZJ4-1", "uniprot_id": "B7YZJ4_DROME", "id": "B7YZJ4-1", "name": "Ataxin-10", "aln": "--MEHVKSETKELVHKLVRLS------------ITENEEE--ISALLKN------------LRLLLTKGRENQETLAESAEFSSFLNAVAFSPVMRTEHRLIHN--------------LSLQVLAN--------------------SVVNNETTQALIWSQHGLKIAEQAYASPLGS---------------SNNVLLMIMYNIYISGHGLITDLVALKTCLQLWRALN-------------------EAQCTYNFEYLHFFLEHFIVQNGRACVACYQKLET--EDR-----VAFLDYVAHYLRENSPNGDVTLFLLQHFAKEFRMKSDCLLRETIKLKHE----LHPR-----EVHTLLRIIASASGSEKYANVYPNDQSLFINV-------SSLLRCIVSAGK-------EPDGGGLDKPMTKLEEVALTSDIDAGYEKKVSYELKTLLVRCSANLLYDNKANKGYCLDTQLLPTLLECTTMDARNPLMREWSILAIRNACINCPEAQQVIAGLTMQGSAPNDILTELNLDMG-----ALRISDRQ----------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P25355-1", "uniprot_id": "ATX10_YEAST", "id": "P25355-1", "name": "Ataxin-10 homolog", "aln": "MPMNNFLDEFNLFDSIITMMKNDPCCVEDYEPIVENLNRIFQRTFNDEEHRKSMANSQLFWERLRDTLEAMLLPASLNENSSIPYTRTVRGLILMMRNLAAENQEIPQKLLLQNLVIRGFLHATSEYVVDTPLIKHLYIACLTCLFNIQQNYSTVDMTTFPALLQFLQYPYGIKLEDGEEEEHFWLPYLFLFKTYLNNDEFSNEFFRDNDTPQKDYYCVRDRIFFDIVTAKFIQDQENSFLIEKG--RNYLDDSKLEITSIDLSVLECISKSLTTASFGKYLNGLEERQPGKFTTLLQILQLVVTSKEDWNTYELTAIMSWCYPILQRLACKDIPAFFNKSCNDYAPSVAIQLHSTLLSCLDIISDLCKFNHVRKFLISYDSVKILVSLLDTFQKNLLRINFLKGNGDTVNEIKITDHEGNKIEDRLLIFNRVNTNESFIRADNFPHCKLVIIEILASLVYAHPEIQDQIRELGGLALILSNCVIDDNDPFIKERSIVCLKFLLKNNAKNQEYVKKMEAQDVVQDDALSKAGFEISVEKGGKVRLVSKEEDPGNENSEIISIDED", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * : :. : : : : :: *: . . . . :: .: :. : . : *:: . . .. : : : :: . . :: :. * : : . * : * . ::* ::*: : : .. : : . : .: * ::.. . .: * .:** *: . . . . . * ::. ..* * : :. : :. :*. :. :*:: : : .:: : .: *: : : *. . . *.: .::: : : . . ", "identical_positions": 21, "similar_positions": 117, "identity": "3.72%" }, { "cls_id": "homologset.agr.MGI:1859307", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I6G901-1", "uniprot_id": "A0A8I6G901_RAT", "id": "A0A8I6G901-1", "name": "Protein unc-93 homolog B1", "aln": "MACAKYHCSHAALSTRRCVCVHPLLDEPECALLLGHLGALMLLDELVGAYPNYNEEEEERRYYRRKRLGVVKNVLAASTGGTLTYGVYLGLLQMQLILHYDETYREVKYGNMGLPDIDSKMLMGINVTPIAALLYTPVLIRFFGTKWMMFLAVGIYALFVSTNYWERYYTLVPSAVALGMAIVPLWASMGNYITRMSQKYYEYSHYKEQDEQGPQQRPPRGSHAPYLLVFQAIFYSFFHLSFACAQLPMVYFLNHYLYDLNHTLFNVKSCGTKSYGILNGFNKTVLRTLPRSRNLIVVESVLMAVAFLAMLLVLGLCGAAYRPTEEIDLRSVGWGNIFQLPFKHVRDFRLRHLVPFFIYSGFEVLFACTGFTLGYGVCSMGLERLAYLLIAYSLGASAASVLGLLGLWLPRSVPLVAGAGLHLLLTLSLFFWAPAPRVLQHSWIFYFVAALWGVGSALNKTGLSTLLGILYEDKERQDFIFTIYHWWQAVAIFVVYLGSSLPMKAKLAVLLVTLVAAATSYLWMENKLQQGLVPRQPRIPKPQHKVRGYRYLEEDNSDESDVEGEQGQGDCAEEEAPQAGP-LGAEPAGPCRRPCPYEQALGGDGPEEQ", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8VCW4-1", "uniprot_id": "UN93B_MOUSE", "id": "Q8VCW4-1", "name": "Protein unc-93 homolog B1", "aln": "MEVEPPLYPVAGAAG-------PQGDEDRHGVPD---GPEAPLDELVGAYPNYNEEEEERRYYRRKRLGVVKNVLAASTGVTLTYGVYLGLLQMQLILHYDETYREVKYGNMGLPDIDSKMLMGINVTPIAALLYTPVLIRFFGTKWMMFLAVGIYALFVSTNYWERYYTLVPSAVALGMAIVPLWASMGNYITRMSQKYYEYSHYKEQDEQGPQQRPPRGSHAPYLLVFQAIFYSFFHLSFACAQLPMIYFLNNYLYDLNHTLINVQSCGTKSQGILNGFNKTVLRTLPRSKNLIVVESVLMAVAFLAMLMVLGLCGAAYRPTEEIDLRSVGWGNIFQLPFKHVRDFRLRHLVPFFIYSGFEVLFACTGFALGYGVCSMGLERLAYLLIAYSLGASASSVLGLLGLWLPRSVPLVAGAGLHLLLTLSLFFWAPAPRVLQHSWIFYFVAALWGVGSALNKTGLSTLLGILYEDKERQDFIFTIYHWWQAVAIFVVYLGSSLPMKAKLAVLLVTLVAAAASYLWMEQKLQQGLVPRQPRIPKPQHKVRGYRYLEEDNSDESDMEGEQGQGDCAEDEAPQAGP-LGAEPAGPCRKPCPYEQALGGDGPEEQ", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9H1C4-1", "uniprot_id": "UN93B_HUMAN", "id": "Q9H1C4-1", "name": "Protein unc-93 homolog B1", "aln": "MEAEPPLYPMAGAAG-------PQGDEDLLGVPD---GPEAPLDELVGAYPNYNEEEEERRYYRRKRLGVLKNVLAASAGGMLTYGVYLGLLQMQLILHYDETYREVKYGNMGLPDIDSKMLMGINVTPIAALLYTPVLIRFFGTKWMMFLAVGIYALFVSTNYWERYYTLVPSAVALGMAIVPLWASMGNYITRMAQKYHEYSHYKEQDGQGMKQRPPRGSHAPYLLVFQAIFYSFFHLSFACAQLPMIYFLNHYLYDLNHTLYNVQSCGTNSHGILSGFNKTVLRTLPRSGNLIVVESVLMAVAFLAMLLVLGLCGAAYRPTEEIDLRSVGWGNIFQLPFKHVRDYRLRHLVPFFIYSGFEVLFACTGIALGYGVCSVGLERLAYLLVAYSLGASAASLLGLLGLWLPRPVPLVAGAGVHLLLTFILFFWAPVPRVLQHSWILYVAAALWGVGSALNKTGLSTLLGILYEDKERQDFIFTIYHWWQAVAIFTVYLGSSLHMKAKLAVLLVTLVAAAVSYLRMEQKLRRGVAPRQPRIPRPQHKVRGYRYLEEDNSDESDAEGEHGDG--AEEEAPPAGPRPGPEPAGLGRRPCPYEQAQGGDGPEEQ", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* . *. : * ** .: *. ****************************:*******:* ******************************************************************************************************************:***:********* ** :**********************************:****:********* **:****:* ***.************* ******************:***********************************:**********************::*******:*********:********:*:**********.********:*****: ******.*********:*..*********************************************.******* ****************.*** **:**::*:.*******:******************** ***:*:* **:*** *** *.**** *:******* ********", "identical_positions": 516, "similar_positions": 44, "identity": "84.73%" }, { "cls_id": "homologset.agr.MGI:1859310", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q91XT9-1", "uniprot_id": "ASAH2_RAT", "id": "Q91XT9-1", "name": "Neutral ceramidase", "aln": "MAKRT--FSSLEAFLIFLLVMMTAITVALLTLLFVTSGTIENHKDSGNHWVSTTQG------------------PTTTQSSPTTQT-PTTQTPDLPPSQNFSGYYIGVGRADCTGQVSDINLMGYGKNGQNAQGLLTRLFSRAFILADPDGSNRMAFVSVELCMISQRLRLEVLKRLQSKYGSLYRRDNVILSATHTHSGPAGFFQYTLYILASEGFSNRTFQYIVSGIVKSIDIAHTNLKPGKVLINKGNVANVQINRSPSSYLQNPPSERARYSSDTDKEMVVLKLVDLNGEDLGLISWFAVHPVSMNNSNHLVNSDNMGYAAYLFEQEKNRGYLPGQ-GPFVAGFASSNLGDVSPNILGPHCVNTGESCDNDKSTCPSGGPSMCMASGPGQDMFESTHIIGRVIYQKAKELHASASQ-----EVTGPVLTAHQWVNMTDVS-VQLN----ATHTVKTCKAALGYSFAAGTIDGVSGLNITQGTTEGNLFWDTLRDQLLGKPSEEIIECQKPKPILIHTGELTKPHPWQPDIVDIQIVTLGSLAIAAIPGEFTTMSGRRLREAVKKEFALYG-MKDMTVVIAGLSNVYTHYITTYEEYQAQRYEAASTIYGPHTLSAYIQLFRALAKAIATDTVANMSSGPEPPFFKN--LIGSLIPNIADRAPIGKQFGDVLQPAKPEYRVGEVVEVVFVGANPKNSAENQTHQTFLTVEKYEDSVANWQIMHNDASWETRFYWHKG--VLGLSNATIHWHIPDTALPGVYRIRYFGHNRKQELLKPAVILAFEGISSPFEIVTT----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9JHE3-1", "uniprot_id": "ASAH2_MOUSE", "id": "Q9JHE3-1", "name": "Neutral ceramidase", "aln": "MAKRT--FSTLEAFLIFLLVIMTVITVALLTLLFVTSGTIENHKDSGNHWFSTTLG------------------STTTQPP------PITQTPNFPSFRNFSGYYIGVGRADCTGQVSDINLMGYGKNGQNARGLLTRLFSRAFILADPDGSNRMAFVSVELCMISQRLRLEVLKRLESKYGSLYRRDNVILSAIHTHSGPAGFFQYTLYILASEGFSNRTFQYIVSGIMKSIDIAHTNLKPGKIFINKGNVANVQINRSPSSYLLNPQSERARYSSNTDKEMLVLKLVDLNGEDLGLISWFAIHPVSMNNSNHFVNSDNMGYAAYLFEQEKNKGYLPGQ-GPFVAGFASSNLGDVSPNILGPHCVNTGESCDNDKSTCPNGGPSMCMASGPGQDMFESTHIIGRIIYQKAKELYASASQ-----EVTGPVLAAHQWVNMTDVS-VQLN----ATHTVKTCKPALGYSFAAGTIDGVSGLNITQGTTEGDPFWDTLRDQLLGKPSEEIVECQKPKPILLHSGELTIPHPWQPDIVDVQIVTVGSLAIAAIPGELTTMSGRRFREAIKKEFALYG-MKDMTVVIAGLSNVYTHYITTYEEYQAQRYEAASTIYGPHTLSAYIQLFRDLAKAIATDTVANMSSGPEPPFFKN--LIASLIPNIADRAPIGKHFGDVLQPAKPEYRVGEVVEVIFVGANPKNSAENQTHQTFLTVEKYEDSVADWQIMYNDASWETRFYWHKG--ILGLSNATIYWHIPDTAYPGIYRIRYFGHNRKQELLKPAVILAFEGISSPFEVVTT----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9NR71-1", "uniprot_id": "ASAH2_HUMAN", "id": "Q9NR71-1", "name": "Neutral ceramidase", "aln": "MAKRT--FSNLETFLIFLLVMMSAITVALLSLLFITSGTIENHKDLGGHFFSTTQSPPATQGSTAAQRSTATQHSTATQSSTATQTSPVPLTPESPLFQNFSGYHIGVGRADCTGQVADINLMGYGKSGQNAQGILTRLYSRAFIMAEPDGSNRTVFVSIDIGMVSQRLRLEVLNRLQSKYGSLYRRDNVILSGTHTHSGPAGYFQYTVFVIASEGFSNQTFQHMVTGILKSIDIAHTNMKPGKIFINKGNVDGVQINRSPYSYLQNPQSERARYSSNTDKEMIVLKMVDLNGDDLGLISWFAIHPVSMNNSNHLVNSDNVGYASYLLEQEKNKGYLPGQ-GPFVAAFASSNLGDVSPNILGPRCINTGESCDNANSTCPIGGPSMCIAKGPGQDMFDSTQIIGRAMYQRAKELYASASQ-----EVTGPLASAHQWVDMTDVT-VWLN----STHASKTCKPALGYSFAAGTIDGVGGLNFTQGKTEGDPFWDTIRDQILGKPSEEIKECHKPKPILLHTGELSKPHPWHPDIVDVQIITLGSLAITAIPGEFTTMSGRRLREAVQAEFASHG-MQNMTVVISGLCNVYTHYITTYEEYQAQRYEAASTIYGPHTLSAYIQLFRNLAKAIATDTVANLSRGPEPPFFKQ--LIVPLIPSIVDRAPKGRTFGDVLQPAKPEYRVGEVAEVIFVGANPKNSVQNQTHQTFLTVEKYEATSTSWQIVCNDASWETRFYWHKG--LLGLSNATVEWHIPDTAQPGIYRIRYFGHNRKQDILKPAVILSFEGTSPAFEVVTI----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q5W7F1-1", "uniprot_id": "ASAH2_DANRE", "id": "Q5W7F1-1", "name": "Neutral ceramidase", "aln": "MASKSRRLSGLEISLIVLFLLMTAVSVALITVLALKQ---ESDKKEE---------------------------VTPEEPS------PSVTPPEKP-------YLIGVGRADCTGPVADLPMMGYANTDQTARGLHTRLFSRAFIVD--DGNKRVVFVTSDIGMVSQRLRLEVFQALKEKYGDLYRQDNVVLSGTHTHSGVGGYFQYTLFMITSKGYIKPSIQAIVSGIVKSIDIAHRNLRPGRIFINKGQVADSNFNRSPHSYMNNPEEERNRYEFNTDKQIVVLKFTDLDGDGIGLLSWFAVHPVSMNYTNRMVSSDNLGYASYIFEQEKNIGFLPGEKGPFVAGFSSSNLGDSSPNIRGPVCVNTGLKCDYINSSCPVGGKKACIAFGPGEDMFESTRIIGENMFKIAKELYGSAKQ-----ELHGPVYGAHQWVNMTDET-VQFN----STHTGRTCKPALGHSFAAGTTDGGGEFNFLQGDTEGDPFWDGIRDAVLGPPSNETKACHQPKPILFSTGEMDSPLPWHPAIVDVQIITIGSLAVVAVPGEFTTMSGRRIREAVKRELEVKEPFTNAEVVVAGLCNIYTHYITTYEEYQIQRYEGASTIFGPHTLSAYIQRYRGLAKAIAHGTIGELPKGPEPPFFDEDKLFNQVRDPVADVAPVGTTFGDVLQEVNPVYKVGEIASVTFVSGNPRHSGDIR-DTTLVTVERFHNDTGSWEIIHNDASWETRFHWIKG--LAGRSQAKVEWHIPQTAQAGTYQIQYFGHY-KQTTENTTVITPYVGTSAAFKVARSFYYF", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VA70-1", "uniprot_id": "NCASE_DROME", "id": "Q9VA70-1", "name": "Pan-ceramidase", "aln": "MANSK-------------MAFLAFLAVSFLCGLVSAT------------------------------------------------------------------YKVGVGRADITGPPVEINFMGYANIKQVGRGIHTRVFARAFVVED-EKGNRVAFVSADAGMMGYGLKREVIKRLQARYGNIYHNDNVAISGTHTHGAPGGFLMHLLYDISILGFVPQTFEVMAQGLYLCIKRATDNLVDGRILLSKTTVLNVNINRSPSSYLRNPAEERAQYEHDTDKTLTQLRFVDLENNLLGAFNWYAVHATSMNNTNRLVTSDNVGYAALLLEKEYNPNKMPGK-GKFVGAFCSSNLGDVSPNIMGPKCSISGNECDLLTSRCPTG-EGDCFASGPGKDMFESTQILGQRLADAALGLLNEQSQESTAREVTGDVRFIHQFVDMPNYNGSTYNPLSRKVDKIRGCQPAMGYSFAAGTTDGPGAFSFEQGTTTDNPMWNFVRD-FIAAPTQEDIKCHEPKPILLATGRATFPYEWQPKIVSDQLLKIGDVIIAAVPCEFTTMAGRRLRNQIRAAASAVG-GIDTEVIIAGLTNIYTSYTVTPEEYQAQRYEAASTIFGPHTHSIYMDVFERLTKAMMRN--ETVDAGPSPPYMND-VMLSLNTGVLFDGHPINTDFGYVKSQPNKEYGINETVKVTYISGNPRN--NLFTEKTYFTIERKINEDR-WKVAYTDASWETKMVWHRTNTILGFSEMDIYWDISPQTLPGEYRIRHSGEYKYILGGK----YPYEGLTHSFTVKED----", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "**. . : ::: ::*::: * * :****** ** :: :***.: * .:*: **:::***:: : .:* .**: : *:. *: **:: *: :**.:*:.*** :*. ***.. .*:: : :: :: *: ::: :. *: .*. * *: *::::.* * . ::**** **: ** .** :*. :*** : *::.**:.: :* :.*:*:*..*** :*::*.***:***: ::*:* * . :**: * **..*.****** **** ** * :* .** .* ** * *:* ***:***:**:*:*. : . * * . .* *: * : **:*:*.: . * .. : *:.*:*:****** ** . :.: ** * .: :*: :** .:. *::* *::*****: :*. * *:* **. *::.:*.: :.*:* *:***:***:*: :: : *:::** *:** * .* **** ****.****:**** * *:: :. *:**: . : **.**::.: :: : * * . ** * . : * :.* ..* ::..**:: : . * .*:*: *:: .******:: * : : * *: : *.*. : .* *:*:: *. : .: * : .* : ", "identical_positions": 240, "similar_positions": 234, "identity": "29.93%" }, { "cls_id": "homologset.agr.MGI:1859314", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O88181-1", "uniprot_id": "BARH2_RAT", "id": "O88181-1", "name": "BarH-like 2 homeobox protein", "aln": "--------------------------------MTAMEGASGSSFGIDTILSGAGSGSPGMMNGDFRSLGEARTTDFRSQATPSPCSEIDTVGTAPSSPISVTLEPPEPHLVTDGPQHHHHLHHGQQPPPPSAPPAQSLQ---------------------------------------------------PSPQQQ---PPPQPQS-AAQQLG--------------------------------------------------------SAAAAPRTSTSSFLIKDILGDSKPLAACAPYSTSVSSPHHTPKQECNAAHESFRPKLEQEDSKTKLDKREDSQSDIKCHGTKEEGDREITSSRES--------PPVRAKKPRKARTAFSDHQLNQLERSFERQKYLSVQDRMDLAAALNLTDTQVKTWYQNRRTKWKRQTAVGLELLAEAGNYSALQRMFPSP-----------------------------YFYHPSLLGSMDST----------------------------TAAAAAAAMYSSMYR---------TPPAPHPQLQRPLVPRVLIHG------------LGPGGQPALNPLSNPIPGTPHPR---------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8VIB5-1", "uniprot_id": "BARH2_MOUSE", "id": "Q8VIB5-1", "name": "BarH-like 2 homeobox protein", "aln": "--------------------------------MTAMEGASGSSFGIDTILSGAGSGSPGMMNGDFRSLGEARTTDFRSQATPSPCSEIDTVGTAPSSPISVTLEPPEPHLVTDGPQHHHHLHHSQQPPPPSAVPAQSLQ---------------------------------------------------PSPQQQ---PPPQPQS-AAQQLG--------------------------------------------------------SAAAAPRTSTSSFLIKDILGDSKPLAACAPYSTSVSSPHHTPKQESNAAHESFRPKLEQEDGKTKLDKREDPQSDIKCHGTKEEGDREITSSRES--------PPVRAKKPRKARTAFSDHQLNQLERSFERQKYLSVQDRMDLAAALNLTDTQVKTWYQNRRTKWKRQTAVGLELLAEAGNYSALQRMFPSP-----------------------------YFYHPSLLGSMDST----------------------------TAAAAAAAMYSSMYR---------TPPAPHPQLQRPLVPRVLIHG------------LGPGGQPALNPLSNPIPGTPHPR---------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9NY43-1", "uniprot_id": "BARH2_HUMAN", "id": "Q9NY43-1", "name": "BarH-like 2 homeobox protein", "aln": "---------------------------------MTMEGASGSSFGIDTILSSASSGSPGMMNGDFRPLGEARTADFRSQATPSPCSEIDTVGTAPSSPISVTMEPPEPHLVADATQHHHHLHHSQQPPPPAAAPTQSLQ---------------------------------------------------PLPQQQQPLPPQQPPPPPPQQLG--------------------------------------------------------SAASAPRTSTSSFLIKDILGDSKPLAACAPYSTSVSSPHHTPKQESNAVHESFRPKLEQEDSKTKLDKREDSQSDIKCHGTKEEGDREITSSRES--------PPVRAKKPRKARTAFSDHQLNQLERSFERQKYLSVQDRMDLAAALNLTDTQVKTWYQNRRTKWKRQTAVGLELLAEAGNYSALQRMFPSP-----------------------------YFYHPSLLGSMDST----------------------------TAAAAAAAMYSSMYR---------TPPAPHPQLQRPLVPRVLIHG------------LGPGGQPALNPLSSPIPGTPHPR---------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q24256-1", "uniprot_id": "BARH2_DROME", "id": "Q24256-1", "name": "Homeobox protein B-H2", "aln": "MTTMPPEMSATTAAPVGSAPSATAHHPAAVGGGMPRPASPAVGSNTTTATATTATRSRFMITDILAGAAAASAAAAAAAAALAAASSGGGRGSPTDSEREQSLVAQHHHHHQQQQQHHHHQQQQQQQQHQQAALQQYIVQQQQLLRFEREREREREREHYRERHSPPGNNPYAHHPMPPHLLAHFPPAHYAVLQQQQQQQQQQQHPHPHHLQLERERLEALHRHGHGLTGDPAQHLSHLSHLSHQQHHPHLHHPMHDERSRSPLMLQQLGGNGGNNNNNNNNSSSASNNNNNNNNSASANSNIISGNSSSSNNNNGSGNGNMLLGGPGSSISGDQASTIDDSDSDDCGGKDDDGDDSMKNGSSANGDSSSHLSLSLSKKQRKARTAFTDHQLQTLEKSFERQKYLSVQDRMELANKLELSDCQVKTWYQNRRTKWKRQTAVGLELLAEAGNYAAFQRLYGGATPYLSAWPYAAAAAAQSPHGATP-SAIDIYYRQAAAAAAMQKPSLPASYRMYQSSIPPGMSLPGMPAPP----PPGAAPMLSGYY--AAAAAAAASAGAQQQQQQPPAASRSPATSQSANSEADCERTSSSSRQRLITPSPPLNPGSPPHRERINEEEDRERDEERDIERERERERERDEDDEEELALEV", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q24255-1", "uniprot_id": "BARH1_DROME", "id": "Q24255-1", "name": "Homeobox protein B-H1", "aln": "---MKDSMSILTQTPS-----------------EPNAAHPQLHHHLS--TLQQQHHQHHLHYGLQPPAVAHSIHSTTTMSSGGSTTTASGIGKPNRSRFMINDILAGSAAAAFYKQQQHHQQLHHHNNNNNSGSSG-----------------GSSPAHSNNNNNINGDNCEASNVAGVGVLP-------SALHHPQPHPPTHPHTHPHALMHPHGKLGHFPPTAGGNGLNVAQYAAAM-----QQHY------------------AAAAAAAAARNNAAAAAAAAAAAAAAGVAAPPVDGGVDGGVGLAPPAGGDLDDSSDYHEENEDCDSGN----MDDHSVCSNGGKDDDGN-SVKSGSTS--DMSG-----LSKKQRKARTAFTDHQLQTLEKSFERQKYLSVQERQELAHKLDLSDCQVKTWYQNRRTKWKRQTAVGLELLAEAGNFAAFQRLYGGS-PYLGAWPYAAAAGAA--HGATPHTNIDIYYRQAAAAAAMQKP-LPYNLYAGVPSVGVGVGVGVGPAPFSHLSASSSLSSLSSYYQSAAAAASAANPGGPHPVAPPPSVGGGSPPSGLVKPIPAHSASASPPPRPPSTPSPTLNPGSPPGRS---------------------VDSCSQSDDEDQIQV--", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . . . . : . : :: .. : . *.. * . *::** : :: : . :: : . . .. .. ... : . . .. :. . . . . . . * . . *..::*: .:... : :** *******:****: **:***********:* :** *:*:* *****************************::*:**:: .. *: :.: .:*:.. ...: . *. * .. . : * . . .. : .* . **:* * ", "identical_positions": 82, "similar_positions": 103, "identity": "12.58%" }, { "cls_id": "homologset.agr.MGI:1859320", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P0DTL6-5", "uniprot_id": "ZTRF1_HUMAN", "id": "P0DTL6-5", "name": "Zinc finger TRAF-type-containing protein 1", "aln": "MSGAEEAGGGGPAAGPAG---SVPAGVGVGVGAGPGAAAGQAAAAALGEAAGPGLPDEAGLAGARQLQLQEAAGDPDAPPKKRLRAAEAAEAAAAAAAAGSGKLEERLYSVLCCTVCLDLPKASVYQCTNGHLMCAGCFIHLLADARLKEEQATCPNCRCEISKSLCCRNLAVEKAVSELPSECGFCLRQFPRSLLERHQKEECQDRVTQCKYKRIGCPWHGPFHELTVHEAACAHPTKTGSELMEILDGMDQSHRKEMQLYNSIFSLLSFEKIGYTEVQFRPYRTDDFITRLYYETPRFTVLNQTWVLKARVNDSERNPNLSCKRTLSFQLLLKSKVTAPLECSFLLLKGPYDDVRISPVIYHFVFTNESNETDYVPLPIIDSVECNKLLAAKNINLRLFLFQIQK", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P0DW87-1", "uniprot_id": "ZTRF1_MOUSE", "id": "P0DW87-1", "name": "Zinc finger TRAF-type-containing protein 1", "aln": "MSGAEEAGGGGPAAGPAG---AVPA--GVGVGAGPGAAAG-PAAAALGEAAGPGIPDEAALAGAR--QLQEAAGDPDAPPKKRLRAAEAAEAAAAAVAAGSGKLEERLYSVLCCTVCLDLPKASVYQCTNGHLMCAGCFIHLLADARLKEEQATCPNCRCEISKSLCCRNLAVEKAVSELPSECGFCLRQFPRSLLERHQKEECQDRVTQCKYKRIGCPWHGPFHELTVHEAACAHPTKTGNELMEILDEMDQSHRKEMQLYNSIFSLLSFEKIGYTEVQFRPYRTDDFITRLYYETPRFTVLNQTWVLKARVNDSERNPNLSCKRTLSFQLLLKSKVTAPLECSFLLLKGPYDDVRISPVIYHFVFTNESNETDYVPLPIIDSVECNKLLAAKNINLRLFLFQIQK", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q08CH8-1", "uniprot_id": "ZTRF1_DANRE", "id": "Q08CH8-1", "name": "Zinc finger TRAF-type-containing protein 1", "aln": "MSSMEERMELGVAAAPGSSSS--------GLGVGP---VGGALDAGPGSAGLAGIQEESGVRRDG----SVGEADPDAPPKKRVRLQEG----------EAGKLEERLYSVLCCTVCLDLPKASVYQCTNGHLMCAGCFIHLLADSRLKEEQATCPNCRCEISKSLCCRNLAVEKAVSELPSECSYCLKQFPRSGLDRHQTEECQDRVTQCKYKRIGCPWQGPFHELSAHEAECCHPSKTGMELMGILDEMDQSHRRELQLYNSIFSLLCFEKIGFTEVQFRPYRTDDFITRLYYETPRFTVLNQTWVLKARVNDSERNPNLSCKRTLAFQLILKSKVNSALECSFLLLKGPYEDIKIKPVIQHHVFSNDANETEYAPLPICDSVECNKLLAAKNINLRLFIFQIQK", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "**. ** * **.*.. *:*.** .* . *. *.*. .*: :*:.: . . .*********:* *. :********************************************:**************************************.:**:***** *:***.*******************:******:.*** *.**:*** *** *** ******:*:**********.*****:****************************************************:***:*****.:.************:*::*.*** *.**:*::***:*.**** *******************:*****", "identical_positions": 297, "similar_positions": 54, "identity": "72.97%" }, { "cls_id": "homologset.agr.MGI:1859324", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D4A1I2-1", "uniprot_id": "D4A1I2_RAT", "id": "D4A1I2-1", "name": "Interleukin-1", "aln": "MNKDKELSAATPWFRHIQDLSSRVWVLQDNILTAVPRKEQTVPVTITLLPCQYLDTLEKNKGDPMYLGVKKPQSCLSCTKNGEQPVLQLREGNILDMYHQKERVKASLFYHKKSGTTSTFESAAFPGWFIAVCSKGSCPLVLTQELGKTFITDFEMTVVH", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9JLA2-1", "uniprot_id": "IL36A_MOUSE", "id": "Q9JLA2-1", "name": "Interleukin-36 alpha", "aln": "MNKEKELRAASPSLRHVQDLSSRVWILQNNILTAVPRKEQTVPVTITLLPCQYLDTLETNRGDPTYMGVQRPMSCLFCTKDGEQPVLQLGEGNIMEMYNKKEPVKASLFYHKKSGTTSTFESAAFPGWFIAVCSKGSCPLILTQELGEIFITDFEMIVVH", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9UHA7-1", "uniprot_id": "IL36A_HUMAN", "id": "Q9UHA7-1", "name": "Interleukin-36 alpha", "aln": "--MEKALKIDTPQQGSIQDINHRVWVLQDQTLIAVPRKDRMSPVTIALISCRHVETLEKDRGNPIYLGLNGLNLCLMCAKVGDQPTLQLKEKDIMDLYNQPEPVKSFLFYHSQSGRNSTFESVAFPGWFIAVSSEGGCPLILTQELGKANTTDFGLTMLF", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :* * :* :**:. ***:**:: * *****:: ****:*:.*::::***.::*:* *:*:: ** *:* *:**.*** * :*:::*:: * **: ****.:** .*****.*********.*:*.***:******: *** : ::.", "identical_positions": 79, "similar_positions": 47, "identity": "49.38%" }, { "cls_id": "homologset.agr.MGI:1859325", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9QYY1-1", "uniprot_id": "I36RA_MOUSE", "id": "Q9QYY1-1", "name": "Interleukin-36 receptor antagonist protein", "aln": "MMVLSGALCFRMKDSALKVLYLHNNQLLAGGLHAEKVIKGEEISVVPNRALDASLSPVILGVQGGSQCLSCGTEKGPILKLEPVNIMELYLGAKESKSFTFYRRDMGLTSSFESAAYPGWFLCTSPEADQPVRLTQIPEDPAWDAPITDFYFQQCD", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D4A1A6-1", "uniprot_id": "D4A1A6_RAT", "id": "D4A1A6-1", "name": "Interleukin-1", "aln": "MMVLSGALCFRMKDSALKVLYLHNNQLLAGGLHAGKVIKGEEISVVPNRALDASLSPVILGVQGGSQCLSCGTEKEPILKLEPVNIMELYLGTKESKSFTFYRRDLGLTSSFESAAYPGWFLCTSPEADQPVRLTQISEDPAWDAPITDFYFQQCD", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9UBH0-1", "uniprot_id": "I36RA_HUMAN", "id": "Q9UBH0-1", "name": "Interleukin-36 receptor antagonist protein", "aln": "-MVLSGALCFRMKDSALKVLYLHNNQLLAGGLHAGKVIKGEEISVVPNRWLDASLSPVILGVQGGSQCLSCGVGQEPTLTLEPVNIMELYLGAKESKSFTFYRRDMGLTSSFESAAYPGWFLCTVPEADQPVRLTQLPENGGWNAPITDFYFQQCD", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ********************************* ************** **********************. : * *.************:************:****************** ***********:.*: .*:************", "identical_positions": 138, "similar_positions": 10, "identity": "88.46%" }, { "cls_id": "homologset.agr.MGI:1859328", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9UKF6-1", "uniprot_id": "CPSF3_HUMAN", "id": "Q9UKF6-1", "name": "Cleavage and polyadenylation specificity factor subunit 3", "aln": "------MSAIPAEESDQLLIRPLGAGQEVGRSCIILEFKGRKIMLDCGIHPGLEGMDALPYIDLIDPAEIDLLLISHFHLDHCGALPWFLQKTSFKGRTFMTHATKAIYRWLLSDYVKVSNIS--------ADDMLYTETDLEESMDKIETINFHEVKEVAGIKFWCYHAGHVLGAAMFMIEIAGVKLLYTGDFSRQEDRHLMAAEIPNIKPDILIIESTYGTHIHEKREEREARFCNTVHDIVNRGGRGLIPVFALGRAQELLLILDEYWQNHPELH---DIPIYYASSLAKKCMAVYQTYVNAMNDKIRKQIN--INNPFVFKHISNLKSMDHFDDIGPSVVMASPGMMQSGLSRELFESWCTDKRNGVIIAGYCVEGTLAKHIMSEPEEITTMSGQ--KLPLKMSVDYISFSAHTDYQQTSEFIRALKPPHVILVHGEQNEMARLKAALIREYE--DNDEVHIEVHNPRNTEAVTLNFRGEKLAKVMG---------------------------------------FLADKKPEQGQRVSGILVK--RNFNYHILSPCDLSNYT-DLAMSTVKQTQAIPYTGPFNLLCYQLQKL---------------------TGDVEELEIQEKPALKVFKNITVIQEPGMVVLEWLANPSNDMYADTVTTVILEVQSNPKIRKGAVQKVSKKLEMHVYS------------KRLEIMLQDIFGEDCVS-VKDDSILS---------VTVDGKTANLNLETRTVECEEGSEDDESLREMVELAAQRLYEALTP-VH", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9QXK7-1", "uniprot_id": "CPSF3_MOUSE", "id": "Q9QXK7-1", "name": "Cleavage and polyadenylation specificity factor subunit 3", "aln": "------MSAIPAEESDQLLIRPLGAGQEVGRSCIILEFKGRKIMLDCGIHPGLEGMDALPYIDLIDPAEIDLLLISHFHLDHCGALPWFLQKTSFKGRTFMTHATKAIYRWLLSDYVKVSNIS--------ADDMLYTETDLEESMDKIETINFHEVKEVAGIKFWCYHAGHVLGAAMFMIEIAGVKLLYTGDFSRQEDRHLMAAEIPNIKPDILIIESTYGTHIHEKREEREARFCNTVHDIVNRGGRGLIPVFALGRAQELLLILDEYWQNHPELH---DIPIYYASSLAKKCMAVYQTYVNAMNDKIRKQIN--INNPFVFKHISNLKSMDHFDDIGPSVVMASPGMIQNGLSRELFESWCTDKRNGVIIAGYCVEGTLAKHIMSEPEEITTMSGQ--KLPLKMSVDYISFSAHTDYQQTSEFIRALKPPHVILVHGEQNEMARLKAALIREYE--DNDEVHIEVHNPRNTEAVTLNFRGEKLAKVMG---------------------------------------FLADKKPEQGQRVSGILVK--RNFNYHILSPCDLSNYT-DLAMSTVKQTQAIPYTGPFYLLYYQLQKL---------------------TGDVEELEIQEKPALKVFKSITVVQEPGMVVLEWLANPSNDMYADTVTTVILEVQSNPKIRKGAVQKVSKKLEMHVYS------------KRLEVMLQDIFGEDCVS-VKDDSVLS---------VTVDGKTANINLETRAVECEEGSEDDESLREMVELAAQRLYEALTP-VH", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8I6AQC0-1", "uniprot_id": "A0A8I6AQC0_RAT", "id": "A0A8I6AQC0-1", "name": "Cleavage and polyadenylation specificity factor subunit 3", "aln": "------HRALPAR-----QLYSLGAGQEVGRSCIILEFKGRKIMLDCGIHPGLEGMDALPYIDLIDPAEIDLLLISHFHLDHCGALPWFLQKTSFKGRTFMTHATKAIYRWLLSDYVKVSNIS--------ADDMLYTETDLEESMDKIETINFHEVKEVAGIKFWCYHAGHVLGAAMFMIEIAGVKLLYTGDFSRQEDRHLMAAEIPNIKPDILIIESTYGTHIHEKREEREARFCNTVHDIVNRGGRGLIPVFALGRAQELLLILDEYWQNHPELH---DIPIYYASSLAKKCMAVYQTYVNAMNDKIRKQIN--INNPFVFKHISNLKSMDHFDDIGPSVVMASPGMIQNGLSRELFESWCTDKRNGVIIAGYCVEGTLAKHIMSEPEEITTMSGQ--KLPLKMSVDYISFSAHTDYQQTSEFIRALKPPHVILVHGEQNEMARLKAALIREYE--DNDEVHIEVHNPRNTEAVTLNFRGEKLAKVMG---------------------------------------FLADKKPEQGQRVSGILVK--RNFNYHILSPCDLSNYT-DLAMSTVKQTQAIPYTGPFYLLYYQLQKL---------------------TGDVEELEIQEKPALKVFKSITVVQEPGMVVLEWLANPSNDMYADTVTTVILEVQSNPKIRKGAVQKVSKKLEMHVYS------------KRLEVMLQDIFGEDCVS-VKDDSVLS---------VTVDGKTANINLETRAVECEEGSEDDESLREMVELAAQRLYEALTPPVH", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9VE51-1", "uniprot_id": "CPSF3_DROME", "id": "Q9VE51-1", "name": "Cleavage and polyadenylation specificity factor 73", "aln": "MTQATGDARMPDEESDLLQIKPLGAGQEVGRSCIMLEFKGKKIMLDCGIHPGLSGMDALPYVDLIEADEIDLLFISHFHLDHCGALPWFLMKTSFKGRCFMTHATKAIYRWMLSDYIKISNIS--------TEQMLYTEADLEASMEKIETINFHEERDVMGVRFCAYIAGHVLGAAMFMIEIAGIKILYTGDFSRQEDRHLMAAEVPPMKPDVLITESTYGTHIHEKREDRENRFTSLVQKIVQQGGRCLIPVFALGRAQELLLILDEFWSQNPDLH---EIPIYYASSLAKKCMAVYQTYINAMNDRIRRQIA--VNNPFVFRHISNLKGIDHFEDIGPCVIMASPGMMQSGLSRELFESWCTDPKNGVIIAGYCVEGTLAKAVLSEPEEITTLSGQ--KLPLNMSVDYISFSAHTDYQQTSEFIRLLKPTHVVLVHGEQNEMSRLKLALQREYE--ADASTDIKFYNPRNTHAVDLYFRGEKTAKVMG---------------------------------------SLAAKNSEVGSKLSGVLVK--RDFKYHLLAPSDLGKYT-DMSMSVVTQRQSIPWGSSLSTLELLLDRIG--------------------AGCVEVLEAERK--LRVFGCIELTVEQKIIVMEWQATHVNDVYADAVLACIMQSELGGTNLKGATKQT--KSEDSRFR------------ECLIETLQDTFGDNCVPKMFEGDLLP---------VTVSGKRAEINLETLAISCAE----DDVLRQMLNTTVQKLHQTLVSAL-", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q06224-1", "uniprot_id": "YSH1_YEAST", "id": "Q06224-1", "name": "Endoribonuclease YSH1", "aln": "---------MERTNTTTFKFFSLGGSNEVGRSCHILQYKGKTVMLDAGIHPAYQGLASLPFYDEFDLSKVDILLISHFHLDHAASLPYVMQRTNFQGRVFMTHPTKAIYRWLLRDFVRVTSIGSSSSSMGTKDEGLFSDEDLVDSFDKIETVDYHSTVDVNGIKFTAFHAGHVLGAAMFQIEIAGLRVLFTGDYSREVDRHLNSAEVPPLSSNVLIVESTFGTATHEPRLNRERKLTQLIHSTVMRGGRVLLPVFALGRAQEIMLILDEYWSQHADELGGGQVPIFYASNLAKKCMSVFQTYVNMMNDDIRKKFRDSQTNPFIFKNISYLRNLEDFQDFGPSVMLASPGMLQSGLSRDLLERWCPEDKNLVLITGYSIEGTMAKFIMLEPDTIPSINNPEITIPRRCQVEEISFAAHVDFQENLEFIEKISAPNIILVHGEANPMGRLKSALLSNFASLKGTDNEVHVFNPRNCVEVDLEFQGVKVAKAVGNIVNEIYKEENVEIKEEIAAKIEPIKEENEDNLDSQAEKGLVDEEEHKDIVVSGILVSDDKNFELDFLSLSDLREHHPDLSTTILRERQSVRVNCKKELIYWHILQMFGEAEVLQDDDRVTNQEPKVKEESKDNLTNTGKLILQIMGDIKLTIVNTLAVVEWTQDLMNDTVADSIIAILMNVDSAPASVKLSSHSCDDHDHNNVQSNAQGKIDEVERVKQISRLFKEQFGDCFTLFLNKDEYASNKEETITGVVTIGKSTAKIDFNNMKILECN----SNPLKGRVESLLN-IGGNLVTPLC", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : .**..:****** :*::**:.:***.****. .*: :**: * :: ::*:*:********..:**:.: :*.*:** ****.*******:* *:::::.*. :: *::: ** *::****:::*. :* *::* .: ********** *****:::*:***:**: **** :**:* :..::** ***:** ** * :** :: . ::. * :*** *:**********::*****:*.::.: ::**:***.******:*:***:* *** **::: .***:*::** *:.::.*:*:**.*::*****:*.****:*:* **.: :* *:*:**.:***:** :: **: *.::.. .:* . .*: ***:**.*:*:. ***. :...:::***** * *.*** ** :: . . .:...**** * * *:* * **.:* *. :: . . :**:**. ::*: .:*: .** :: *:: : : : *:: : : :: : * * *::: * : : *:** ** **:: : ::: : * : :. : . : : ::: **: . : ... . **:. . *:::::. : : .: *: :: : : *.. : ", "identical_positions": 251, "similar_positions": 244, "identity": "31.65%" }, { "cls_id": "homologset.agr.MGI:1859333", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZGB1-1", "uniprot_id": "NFAT5_RAT", "id": "D3ZGB1-1", "name": "Nuclear factor of activated T-cells 5", "aln": "-------------------------------------------------------------------------MPSDFISLLSADLDLESPKSLYSRDSLK--------------LHPSQNFHRAGLLEESVYDLLPKELQLPPPRETSAASMSQTSGGEAGSPPPAVVAADASSAPSSS-MGGACSSFTTSSSPTIYSTSVTDSKAMQVES---------CSSAVGVSNRGVSEKQLTGNTVQQHPSTPKRHTVLYISPPPEDLLDNSRMSCQDEGCGLESEQSCS-------------MWMEDSPSNFSNMSTSS---------------------------------------YN------------DNTEVPRKSRKRNPKQRPGVKRRDCEESNMDIFDADSAKAPHYVLSQLTTDNKGNSKAGNGTLDSQKGTGVKKSPMLCGQYPVKSEGK--------------------------------------------ELKIVVQPETQHRARYLTEGSRGSVKDRTQQGFPTVKLEGHNEPVVLQVFVGNDSGRVKPHGFYQACRVTGRNTTPCKEVDIEGTTVIEVGLDPSSNMTL----AVDCVGILKLRNADVEARIGIAGS---KKKSTRARLVFRVNITRKDGSTLTLQTPSSPILCTQPAGVPEILKKSLHSCSVKGEEEVFLIGKNFLKGTKVIFQENVS--------------------DENSWKSEAEIDMELFHQNHLIVKVPPYHDQHITLPVSVGIYVVTNAGRSHDVQPFTYTPDPAAG-ALSVNVKKEISSPARPCSFEEALKAMKTTGCNVDKVTILPNALITPLISSSMIKTEDVTPMEVTSEKRSSPIFQTTKTVGSTQQTLETISNIAGN-ASFSSPSSS-HLSPENENQQQLQPKAYNPETLTTIQTQDISQPGTFPAVSASSQLPSSDALLQQAAQFQTRDAQSRDTMQSD-SVVNLSQLTEAPQQQQ-SPLQEQAQ-----IPSNIFPSPNSVSQLQSTIQQLQAGSFTGSTASGSNGSVDLVQQVLEAQQQLSSVLFSTPDGNENVQEQLNADIFQ-VSQIQNSVSPGMFSSTESAVHTRPDNLLPGRADSVHQQTENTLSSQQQQQQQQQQQQQQQVIESSAAMVMEMQQSICQAAAQIQSELFPSAASANGSLQQSPVYQQPSHMMSALPTSEDMQMQCELFSSPPAVSGNETSTTTTPQVATPGSTMFQPPNSGDGEETGAQAKQIQSSVFQTMVQMQHSGDSQPQVNLFSSTKNIMSVQSNGTQQQGNSLFQQGSEMLSLQSGSFLQQSSHSQAQLFHPQNPIADAQSLSQETQGPMFHSANPIVHSQTSTASSEQLQPSMFHSQSTIAVLQGSSVPQDQQ--SPNIYLSQSSISNLQTNTVAQEEQISFFSAQNSISPLQSTSNTEQQAAFQQQPPISHIQTPLLSQEQAQPSQQGLFQPQVALGSLPANPMPQNQQGPIFQTQRPIVGMQSNSPSQEQQQQQQQQQQQQQQQQQQ--SILFSNQNAMATMASQKQPPPNMIFSPNQNPMASQEQQNQSIFHQQSNMAPMNQE--QQPMQFQNQPTVSSLQNPGPTPSESPQTSLFHSSPQIQLVQGSPSSQEQQVTLFLSPASMSALQTSINQPDMQQSPLYSPQNNIPGIQGSTSSPQPQ-AALFHNTTGGTINQLQNSPGSSQQTSGMFLFGIQNNCSQLLTSGPATLPEQLMAINQPGQPQNEGQSSVTTLLSQQMPESAPLASSVNNSQNMEKIDLLVSLQS----QGNNLTGSF--------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9WV30-1", "uniprot_id": "NFAT5_MOUSE", "id": "Q9WV30-1", "name": "Nuclear factor of activated T-cells 5", "aln": "-------------------------------------------------------------------------MPSDFISLLSADLDLESPKSLYSR--------------------------------ESVYDLLPKELQLPPPRETSVASMSQTSGGEAGSPPPAVVAADASSAPSSSSMGGACSSFTTSSSPTIYSTSVTDSKAMQVES---------CSSAVGVSNRGVSEKQLTGNTVQQHPSTPKRHTVLYISPPPEDLLDNSRMSCQDEGCGLESEQSCS-------------MWMEDSPSNFSNMSTSS---------------------------------------YN------------DNTEVPRKSRKRNPKQRPGVKRRDCEESNMDIFDADSAKAPHYVLSQLTTDNKGNSKAGNGTLDSQKGTGVKKSPMLCGQYPVKSEGK--------------------------------------------ELKIVVQPETQHRARYLTEGSRGSVKDRTQQGFPTVKLEGHNEPVVLQVFVGNDSGRVKPHGFYQACRVTGRNTTPCKEVDIEGTTVIEVGLDPSNNMTL----AVDCVGILKLRNADVEARIGIAGS---KKKSTRARLVFRVNITRKDGSTLTLQTPSSPILCTQPAGVPEILKKSLHSCSVKGEEEVFLIGKNFLKGTKVIFQENVS--------------------DENSWKSEAEIDMELFHQNHLIVKVPPYHDQHITLPVSVGIYVVTNAGRSHDVQPFTYTPDPAAG-ALNVNVKKEISSPARPCSFEEAMKAMKTTGCNVDKVTILPNALITPLISSSMIKTEDVTPMEVTSEKRSSPIFQTTKSIGSTQQTLETISNIAGG-APFSSPSSSSHLTPESENQQQLQPKAYNPETLTTIQTQDISQPGTFPAVSAASQLPSSDALLQQATQFQTREAQSRDTIQSD-TVVNLSQLTEASQQQQ-SPLQEQAQTLQQQIPSNIFPSPSSVSQLQSTIQQLQAGSFTGSAAGGRSGSVDLVQQVLEAQQQLSSVLFSTPDGNENVQEQLNADIFQ-VSQIQNSVSPGMFSSAESAVHTRPDNLLPGRADSVHQQTENTLSNQQQQQQQQQQ-----VMESSAAMVMEMQQSICQAAAQIQSELFPSAASASGSLQQSPVYQQPSHMMSALPTNEDMQMQCELFSSPPAASGNETSTTTTPQVATPGSTMFQTPSSGDGEETGAQAKQIQNSVFQTMVQMQRSGDSQPQVNLFSSTKNIMSVQNNGTQQQGNSLFQQGSEMMSLQSGNFLQQSSHSQAQLFHPQNPIADAQNLSQETQGSIFHSPNPIVHSQTSTASSEQLQPSMFHSQNTIAVLQGSSVPQDQQ--SPNIFLSQSSINNLQTNTVAQEEQISFFAAQNSISPLQSTSNTEQQAAFQQQPPISHIQTPILSQEQAQPSQQGLFQPQVALGSLPPNPMPQNQQGPIFQTQRPIVGMQSNSPSQEQQQQQQQQQQQQQQQQQQQQSILFSNQNAMATMASQKQPPPNMMFSPNQNPMASQEQQNQSIFHQQSNMAPMNQE--QQPMQFQNQPTVSSLQNPGPTQSESPQTSLFHSSPQIQLVQGSPSSQDQQVTLFLSPASMSALQTSINQPDMQQSPLYSPQNNIPGIQGSTSSPQPQ-ATLFHNTTGGTINQIQNSPGSSQQTSGMFLFGIQNNCSQLLTSGPATLPDQLMAINQQGQPQNEGQSSVTTLLSQQMPETSPLASSVNSSQNMEKIDLLVSLQS----QGNNLTGSF--------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O94916-1", "uniprot_id": "NFAT5_HUMAN", "id": "O94916-1", "name": "Nuclear factor of activated T-cells 5", "aln": "-------------------------------------------------------------------------MPSDFISLLSADLDLESPKSLYSR--------------------------------ESVYDLLPKELQLPPSRETSVASMSQTSGGEAGSPPPAVVAADASSAPSSSSMGGACSSFTTSSSPTIYSTSVTDSKAMQVES---------CSSAVGVSNRGVSEKQLTSNTVQQHPSTPKRHTVLYISPPPEDLLDNSRMSCQDEGCGLESEQSCS-------------MWMEDSPSNFSNMSTSS---------------------------------------YN------------DNTEVPRKSRKRNPKQRPGVKRRDCEESNMDIFDADSAKAPHYVLSQLTTDNKGNSKAGNGTLENQKGTGVKKSPMLCGQYPVKSEGK--------------------------------------------ELKIVVQPETQHRARYLTEGSRGSVKDRTQQGFPTVKLEGHNEPVVLQVFVGNDSGRVKPHGFYQACRVTGRNTTPCKEVDIEGTTVIEVGLDPSNNMTL----AVDCVGILKLRNADVEARIGIAGS---KKKSTRARLVFRVNIMRKDGSTLTLQTPSSPILCTQPAGVPEILKKSLHSCSVKGEEEVFLIGKNFLKGTKVIFQENVS--------------------DENSWKSEAEIDMELFHQNHLIVKVPPYHDQHITLPVSVGIYVVTNAGRSHDVQPFTYTPDPAAAGALNVNVKKEISSPARPCSFEEAMKAMKTTGCNLDKVNIIPNALMTPLIPSSMIKSEDVTPMEVTAEKRSSTIFKTTKSVGSTQQTLENISNIAGN-GSFSSPSSS-HLPSENEKQQQIQPKAYNPETLTTIQTQDISQPGTFPAVSASSQLPNSDALLQQATQFQTRETQSREILQSDGTVVNLSQLTEASQQQQQSPLQEQAQTLQQQISSNIFPSPNSVSQLQNTIQQLQAGSFTGSTASGSSGSVDLVQQVLEAQQQLSSVLFSAPDGNENVQEQLSADIFQQVSQIQSGVSPGMFSSTEPTVHTRPDNLLPGRAESVHPQSENTLSNQQQQQQQQQQ-----VMESSAAMVMEMQQSICQAAAQIQSELFPSTASANGNLQQSPVYQQTSHMMSALSTNEDMQMQCELFSSPPAVSGNETSTTTTQQVATPGTTMFQTSSSGDGEETGTQAKQIQNSVFQTMVQMQHSGDNQPQVNLFSSTKSMMSVQNSGTQQQGNGLFQQGNEMMSLQSGNFLQQSSHSQAQLFHPQNPIADAQNLSQETQGSLFHSPNPIVHSQTSTTSSEQMQPPMFHSQSTIAVLQGSSVPQDQQ--STNIFLSQSPMNNLQTNTVAQEA---FFAAPNSISPLQSTSNSEQQAAFQQQAPISHIQTPMLSQEQAQPPQQGLFQPQVALGSLPPNPMPQSQQGTMFQSQHSIVAMQSNSPSQEQQQQQQQQQQQQQQQQQS---ILFSNQNTMATMASPKQPPPNMIFNPNQNPMANQEQQNQSIFHQQSNMAPMNQE--QQPMQFQSQSTVSSLQNPGPTQSESSQTPLFHSSPQIQLVQGSPSSQEQQVTLFLSPASMSALQTSINQQDMQQSPLYSPQNNMPGIQGATSSPQPQ-ATLFHNTAGGTMNQLQNSPGSSQQTSGMFLFGIQNNCSQLLTSGPATLPDQLMAISQPGQPQNEGQPPVTTLLSQQMPENSPLASSINTNQNIEKIDLLVSLQN----QGNNLTGSF--------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AB32TU54-1", "uniprot_id": "A0AB32TU54_DANRE", "id": "A0AB32TU54-1", "name": "Nuclear factor of activated T-cells 5", "aln": "-------------------------------------------------------------------------MPSDFTSLFSADIDLDSPKSLYSK--------------------------------ESVYDLLPKELQLPSSGVQSAAAMSQKSGGEAGPPPPAALAADASSASSAMSSGSPRSAFPTSASD--RSTVHDSGSSGDVSS---------RRKSEAVENKPSGRD----KGVQQTQMTPSKRPVLNISPPPEDLFDDSHMSCQDD-LLLDSEQSSS-------------IWIENSVSNFSIVSSSS---------------------------------------YN------------DNTEVPRKARKCTPRQKPGPKPVSAEEASMDVFDADSAKGPHFVLSQLGPDSKTCSKASS---DGPQVSALKGG-VLSCQYPQKGEGK--------------------------------------------ELKIVVQPETQHRARYLTEGSRGSVKDQTQQGFPTIKLEGVKESVVMQIFVGNDAGRVKPHGFYQACRVTGRNTTACREVDIEGTTVIEVPMDPSSNMTLPCLCSVDCVGILKLRNADVEARIGVAGS---KKKSTRARLVFRVNIPRPDGSALTLQTSSSPILCTQPAGAPEILKKSLHSCSVKGGNEVFIIGKNFLKGTKVIFQENASA-------------------DDKSWKAEADIDMEFFHQNHLIVKVPPYQNPAITSPISVGIYVVTNAGRSHDVQQFTYTPEPVVD----SSVKKEDLPPVTPCCFEQ--------------IKVIDTAVMTPGLP--LVKREEATPMEVSGN--PSDFKQTSEVINSAQQALDMSTEISTNNCKFSSPLAH----PTREPDQSQNSVFSNKEPFNTIQEQNLASSGSFHVPNKSLLQQGVQPFLLEHRDRLGQEMPG----SSGSSVVALSQLDDNPQQQL-----------------SLLP-PDEVAQLEQAVRQLQAKGYCG----------------------------------------------------------------------------------IQLQSENSLSKQRQHQLQQQQ-----------QQIQQQQHQIHQQQQQIQQQQQHIQHQE----QQIQLQQQHHHQQQALEN-----LQHQLFQPQVQIHCSSEQQSSSQGMVQNGSSLFQSTPS----------------------QQQ--------------------------QQQQATLFQQG-------AGFLQQQPSHSSPSMFHNTTAMTEAQ----SPQESLFHT-------QKTSPNQDQVQASIFQSN--LSVLSGSNMSSEAQPSAASMFLPQNTVPAQLSVNANQPQQLAFLTSMQTSLEAPSVFQTPTQLSPIQQG------TPMDQQQSPQHAQPGSMFQSISQSPSKLTPGQQQQAGLLLG--------SLNSPITQEQSSN----------------LLFGGQVQIGSMNN--------------SSLASSEQQNTPLPFAQAGLVTVRQQEASEPMTFQDQTAMVVN--------LSSNKPIFQDQQPMQLAPSSNPGSSQSVNLFMAQSNMQGGMT-------TQEALFAPQGDVGGIQTSTSSPVQQPGQLFQTTMSGSLNQP-----NQDQQTDLFLFEIQNECRQLMNSQGSTLSNQIITINQPGQSQQESDGQIQSLLGQAMPDPGAVQSTLTTSQNMEKIDDLLSYHQGDTPHSKKVAGSSPSWVSWHFCVELACSPRVRVGFLRVLRFSPQSKGMQYR", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A8JUV3-1", "uniprot_id": "A8JUV3_DROME", "id": "A8JUV3-1", "name": "Nuclear factor of activated T-cells 5", "aln": "MRFTYNQYKHYESGYRIPSKMHNLSHNNNNNSNNNNNGGGHTNNNNNGNNSGHHYAHHNNSNNGGNNNTNFQAYQHHYKSNFGMRMTMSTNSTMSARIHRKGFRIPSKRQPGKGLPGKLHTITRTGPGKMVPGKRIPQRPHPPPCDNSNDSGLGFDQHTELRSSAGAGGVTDPAANGGSGSNSGQRSSLLVNSALTNTVAAAAAAAAAAVASNTLQQHQQHHQQQQQQQQQQQQQQQQQQQQQQQQQHSPQQHLIRAIPVSRSRNNTKVMAHCLEDLDLISASSEDSSTIATPAGLDEDTGFVNDTKTTTTGGNSSSDPFGGVFQATEAAVAAAVNAFNLQQQQHSVQQQQHQLFQYNGLLLQPQQQLQQQQSHHQQQQQQQQHHRHGKHIKRKKLECNQVELDNDDACSEDEFIRKIASSVTMSPTLEATPSPPPIVASVAPATTIVSLLPLISSGNSNNNNNNNNIETKFISARNVTRVANKRQPTTPLNSVASSNDGQVQLEILSQPEQQHRARYQTEGSRGAVKDRSGNGFPIVRLTGYDKVAVLQVFIGTDIGRVAPHMFYQACKVAGKNSTQCNEKKVDGTMVIEIDFKPETDMTI----TCDCVGILKERNVDVEHRFPEHLAQKNKKKSTRCRMVFRTQLTRDDGTTETLQVCSNPIICTQPPGVPEICKKSLNSCPVDGGLELFIIGKNFLKDTHVVFQETYDSVNGDDPATEIAVRQQLIGGTAALWEQSVLPDKEYLHQTHLICTVPPYLHQNILKPVQVQVSIVS-SGKKSEPHTFTYTAKGQYTTLAAASTLSNTIHAQDVSGFMD-----------------------TTSASNASGSSGWSAAGGSGNNTSTGDNVEAKHEIDSGMMPPPITTQIPMGVRRSSLPSVT----PMITDQQLVHLNAVAAS--AEALKTELDDSNSHSPLTGESTPDSPNAALQYHRFAR----------KPSLDTIMYDQSNSLPGFPT-------------------VVAPATAAAVAAAVDIDPTAVAVA----------------------------------------------------------------------------------VELAVKNEIVKHVVQQHQQMQ-----------EQMHEQQQQQQQQQQQQQQQQ-----------QQQPQQQQQ-------------QQVHKFIDELTKSTSVVSSNGTTEPALFTTSAVIDHALT----------------------------------------------------------------------DILQAKVGIAPPNVVLERSLSLSSTNSSSSMSG------------SESSPNSSPLTQDIILNSEPAAALAGAAALGGPAP----VDVTGGLSTDIIMNPAVSPSTILCSANGAATAVVPNILAPHQVTMANSILN--------DIAMQPEPTQQDAAVAALALSNIMMSP-PTAASGVGVG--------DTLPPTPATMQP-------------------------------------------EVAATATSTAVSNMIIKAAADFITTQEQ---EQHHYHHHGRIHSHSPQAAVGVSGNPAETASDPLVDLLLNHSNTPETAAAAAAAVAVEAANFQS-------MNHSHHSHHGHHGHSHGHGHSRVTG---HVSGHVTSHHRGHHLPVVPPTPQESLIVALASENALQKSVATAAVTTNGAVMTQQASAPNTAGSILPAAVGAVAAAAAVAVQPPIPQELTTMSDQDLISYIN-----PSTFDQL---------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .: * :. : :.: .:: :: . :*:. : *. . :.:. . * ... * .:*.:: .: .. *:: ..:: : . : * * . .:: .. : ** :*.:: : *. . . . * :: :.:... * ::::: :. : .:** ** :::. :: :: ::: . *.. :* *.* . . .: :: .. . .. :.: . : * ..*: :*:*: *** ****** ******:***:: :*** ::* * .: .*:*:*:*.* *** ** *****:*:*:*:* *.* .::** ***: :.*..:**: : ******* **.*** *: : ******.*:***.:: * **:: ***. *.**:****.*.*** ****:**.*.* *:*:*******.*:*:***. . *: .. * * :**.*** .**** . * *:.* : :*: :*:. : : ****.. .. .: . . * : *. . . :. : .. ::.. :.* . ::*. . * * . :* : . :: ...:. . . :. * ... .: .* . . . * .: : :: : . :. :* : .: :* ** * : : *:. * * *.: ** ** :::. . :: ::::: . : . : : . : ..:. . .: . . . ::.... : :: .. :.* *: : :. . . . : : . . . ..: .* . :: . .* * . . .* . . *.. . : :.: . .:: : :: : : . . * * . . . . : : . .: :.. : * . . . .::: .::. * : :. .: : .* . .: .. :: . . .: ..: . . . : *:* . ... ", "identical_positions": 199, "similar_positions": 401, "identity": "10.82%" }, { "cls_id": "homologset.agr.MGI:1859353", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9QXP6-1", "uniprot_id": "MKRN1_MOUSE", "id": "Q9QXP6-1", "name": "E3 ubiquitin-protein ligase makorin-1", "aln": "MAEAAAPGTTATTSGAGAAAAAVA----AASLTSIPTVAAPSPGAGGGGGGSDGSGGG-------------------------------WTKQVTCRYFMHGVCKEGDNCRYSHDLSDSPYGVVCKYFQRGYCVYGDRCRYEHSKPLKQEEVTATDLSAKPSLAASSSLSSGVGSLAEMNSGEAESRNPSFPTVGAGSEDWVNAIEFVPGQPYCGRTAPSCTEVPPQGSVTKEESE--------------KEPTTVETKKQLCPYAAVGECRYGENCVY-LHGDSCDMCGLQVLHPVDAAQRSQHIKSCIEAHEKDMELSFAVQRTKDMVCGICMEVVYEKANPSERRFGILSNCNHTYCLKCIRKWRSAKQFESKIIKSCPECRITSNFVIPSEYWVEEKEEKQKLIQKYKEAMSNKACRYFDEGRGSCPFGGNCFYKHAYPDGRREEPQ--RQKVGTSSRYRAQRRSHFWELIEEREN-NPFDNDEEEVVTFELGEMLLMLLAAGGDDELTDSEDEWDLFHDELEDFYDLDL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A0G2QC40-1", "uniprot_id": "A0A0G2QC40_RAT", "id": "A0A0G2QC40-1", "name": "RING-type E3 ubiquitin transferase", "aln": "MAEAAAPGTTATTSGAGAAAAAVA----AASLTSIPTVAAPSPGAGGGGGGSDGSGGG-------------------------------WTKQVTCRYFMHGVCKEGDNCRYSHDLSDSPYGVVCKYFQRGYCVYGDRCRYEHSKPLKQEEVTATDLSAKPSPAASSSLPSGVGSLAEMNPGEAESRNPNFPTVGAGSEDWVNAIEFVPGQPYCGRTAPSCTEVPLQGSVTKEESE--------------KEPTTVETEKQLCPYAAVGECRYGENCVY-LHGDSCDMCGLQVLHPMDAAQRSQHIKSCIEAHEKDMELSFAVQRSKDMVCGICMEVVYEKANPSERRFGILSNCNHTYCLKCIRKWRSAKQFESKIIKSCPECRITSNFVIPSEYWVEEKEEKQKLIQKYKEAMSNKACRYFDEGRGSCPFGGNCFYKHAYPDGRREEPQ--RQKVGTSSRYRAQRRSHFWELIEEREN-NPFDNDEEEVVTFELGEMLLMLLAAGGDDELTDSEDEWDLFHDELEDFYDLEL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9UHC7-1", "uniprot_id": "MKRN1_HUMAN", "id": "Q9UHC7-1", "name": "E3 ubiquitin-protein ligase makorin-1", "aln": "MAEAATPGTTATTSGAGAAAATAA----AASPTPIPTVTAPSLGAGGGGGGSDGSGGG-------------------------------WTKQVTCRYFMHGVCKEGDNCRYSHDLSDSPYSVVCKYFQRGYCIYGDRCRYEHSKPLKQEEATATELTTKSSLAASSSLSSIVGPLVEMNTGEAESRNSNFATVGAGSEDWVNAIEFVPGQPYCGRTAPSCTEAPLQGSVTKEESE--------------KEQTAVETKKQLCPYAAVGECRYGENCVY-LHGDSCDMCGLQVLHPMDAAQRSQHIKSCIEAHEKDMELSFAVQRSKDMVCGICMEVVYEKANPSERRFGILSNCNHTYCLKCIRKWRSAKQFESKIIKSCPECRITSNFVIPSEYWVEEKEEKQKLILKYKEAMSNKACRYFDEGRGSCPFGGNCFYKHAYPDGRREEPQ--RQKVGTSSRYRAQRRNHFWELIEERENSNPFDNDEEEVVTFELGEMLLMLLAAGGDDELTDSEDEWDLFHDELEDFYDLDL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q13434-1", "uniprot_id": "MKRN4_HUMAN", "id": "Q13434-1", "name": "Putative E3 ubiquitin-protein ligase makorin-4", "aln": "MAEAAAPGTTVTTSGAGAAAAEAAETAEAVSPTPIPTVTAPSPRAGGGVGGSDGSDGSGGRGDSGAYDGSGACGGSDACDGSGDSSGDSWTKQVTCRYFKYGICKEGDNCRYSHDLSDRLCGVVCKYFQRGCCVYGDRCRCEHSKPLKQEEATATELTTKSSLAASSSLSSIVGPLVEMNTNEAESRNSNFATVVAGSEDWANAIEFVPGQPYCGRTVPSCTEAPLQGSVTKEESE--------------EEQTAVETKKQLCPYAAVGQCRYGENCVY-LHGDLCDMCGLQVLHPMDAAQRSQHIQACIEAHEKDMEFSFAVQRSKDKVCGICMEVVYEKANPNEHRFGILSNCNHTFCLKCIRKWRSAKEFESRIVKSCPQCRITSNFVIPSEYWVEEKEEKQKLIQKYKEAMSNKACKYFDEGRGSCPFGENCFYKHMYPDGRREEPQ--RQQVGTSSRNPGQQRNHFWEFFEEGANSNPFD-DEEEAVTFELGEMLLML-------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q4VBT5-1", "uniprot_id": "MKRN1_DANRE", "id": "Q4VBT5-1", "name": "Probable E3 ubiquitin-protein ligase makorin-1", "aln": "MAEAAAASTAAPAVIGG------------------------------------------------------------------------WTKHVTCRYFMHGLCKEGENCRYSHDLSSCKQTMICKFFQKGCCAFGDRCRYEHTKPSKQDEVPS----SKPSMPLTAAP--LAGTPEPVSDGPGGTTGAQEKPQGSGAVDWVNAAEFVPGQPYCGRADPVLCEGP--GPLIEEEYE--------------KEQANKEMKKQLCPYAAVGECRYGLNCAY-LHGDVCDMCGLQVLHPSDTSQRSQHIRACIEAHEKDMEISFAIQRSKDMMCGVCMEVVFEKTNPSERRFGILSNCCHCYCLKCIRKWRSAKQFESKIIKSCPECRITSNFVIPSEYWVEDKEEKQQLIQKYKDGMGTKPCRYFDEGRGTCPFGANCFYKHAFPDGRLEEPQPQRRQNGSNGRNRNTRRTHLWDLLDERENSDSFDNEDEEMVRFELSEMLLMLLAAGTDDDVTDSEDEWDLFHEELDDYYELYL", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VY21-1", "uniprot_id": "Q9VY21_DROME", "id": "Q9VY21-1", "name": "RING-type E3 ubiquitin transferase", "aln": "-----------------------------------------------------------------------------------------------------------------MTSSRQNLHKICRYRLRGNCRFDDLCRYSHDVLQ----------NDNLRPQISNNADEVVG------HANRYSRPMT----------GANA-------------------------------------------------------------------------------------------------------------TEEMKLSFAIAKSQDKMCGICLETVVKKRG-RECRFGILPKCKHIFCLTCIRRWRQAEYIEDNVKRGCPECRVFSEFVCPSAYWVDTKEEKDKLLSEYRAAMGAKDCKYFNGGLGKCPFGTNCFYNHRSLAGD----------------NRIQRH-------------------------------------SMEDDDF----------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VY20-1", "uniprot_id": "Q9VY20_DROME", "id": "Q9VY20-1", "name": "RING-type E3 ubiquitin transferase", "aln": "-----------------------------------------------------------------------------------------------------------------MSYRRS--QTICRFHLLGICRFGDLCRFSHDETTP---------NDNQSPQISEIADEVVENEQVVASTSSYSRQMT----------WANAPEFVPRYKANSADFQA-------------------------------------TEGVQDICPYGGSCIWGSKCSYPLHMEICKMCDLYCLHPMDQNQRRAHNRECLEQHEQAMELSFAIARSKDKMCGICFDTVVEKKG-RERRFGILSKCKHIFCLTCIRTWRQAHQFEATVTRGCPECRVFSEFVCPSAYWVDTKEEKDKLLSEYRAAMGAKDCKYFNGGLGKCPFGNKCFYRHHRRCDD----------------NQTQSN-------------------------------------AVNSD------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VP20-1", "uniprot_id": "Q9VP20_DROME", "id": "Q9VP20-1", "name": "RING-type E3 ubiquitin transferase", "aln": "----------------------------------------------------------------------------------------------------MSAVTSSDTAISGMALGRS--QTICRYYVRGICRFGELCRFSHDLSRGRPECEE-QVATDVLPKPSTSSSSTIGSR----SASISSQQRN----------WANAPVFVPSQKRYTAHEQSEFETTVDPEAVMEAQAGASYDTLAPGVSWAEVVGGPSSLNKEDYGEENSSCAWGEFSAYPIHMELCEMCDQYCLHPTDQVQRRSHNRECLQQHEQAMELSFAIARSKDKTCGICFDTIMEKAG-REKRFGILPNCNHIFCLECIRTWRQAKQFENKITRACPECRVCSDFVCPSAFWMETKEEKDKLLNDYRAALGAKDCKYFKKGEGKCPFGNKCFYKHALPNGDIVDVG------LPKRTRKLQSQNEIIDLLD------IYLWDYVDRRDYHWLEMISSDITSSESSDYSDED------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VVS2-1", "uniprot_id": "Q9VVS2_DROME", "id": "Q9VVS2-1", "name": "RING-type E3 ubiquitin transferase", "aln": "---------------------------------------------------------------------------------------------------MSTVASNDQHVDTGVLPVPSTNSPSSQIEQKGNEAIVPNYKAATAGEQGEAQAGATCTTVAVRPSGVATSADIVKGSSSVSSHVQPSWRSS------------------------------------------------------------------------------------------------------------------------------------FARSQDKKCGICFETIMEKEG-GDKRFGILPSCNHVFCFQCICTWRHATQYAYQVTRACPECRVWSNFVCPSAFWVEEKVAKDQLINDHLAAMRARDCKYFKQGQGVCLFGNKCFYKHSIPNADYVDVG------LPTHALGLPIPSDFSGLGN-------------CLILVPFPNMFFDDFSNSDDYDFSDVN------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q02799-1", "uniprot_id": "LEE1_YEAST", "id": "Q02799-1", "name": "Zinc finger protein LEE1", "aln": "----------------------------------------------------------------------------------------------------MDAFENMSVSNHPGGNARRNSQSANEMLASQIQDFQNIPRSFNDSNANVNLSKN-CTVGNQLPFSSRQQKIIMEHLLITKNNSQQQKDYS-----------------------------------------------------------------------------------------------------------HVPCKFFKMGNCQAGSSCPFSHSPDIISSANNLPCKYFAKGNCKFGNKCVNAHVLPNGFKMNSKEPIDITPPSQNNYLSHARSASFSTYTSPPLSAQTEFSHSASNANYFSSQYLMYSPQKSPEALYTEFFSPPSSSSSYINYSYNNSNINAYS-----PVSSSSSNIWQEQGQTTLSNPSVNQNLRYRTGPAIQEESDNEIEDLLIHNFNSRYCHE--------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . : . : : : * . . :*.. : . * : :... . * : .. : . : : .: : . : . ..: .: ", "identical_positions": 4, "similar_positions": 37, "identity": "0.75%" }, { "cls_id": "homologset.agr.MGI:1859384", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O35543-1", "uniprot_id": "HPGDS_RAT", "id": "O35543-1", "name": "Hematopoietic prostaglandin D synthase", "aln": "----------------------------------------------MPNYKLLYFNMRGRAEIIRYIFAYLDIKYEDHRIEQADWPKIKPTLPFGKIPVLEVEGLTLHQSLAIARYLTKNTDLAGKTELEQCQVDAVVDTLDDFMSLFPWA--EENQDLKERTFNDLLTRQAPHLLKDLDTYLGDKEWFIGN-YVTWADFYWD-ICSTTLLVLKPDLLGIYPRLVSLRNKVQAIPAISAWILKRPQTKL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9JHF7-1", "uniprot_id": "HPGDS_MOUSE", "id": "Q9JHF7-1", "name": "Hematopoietic prostaglandin D synthase", "aln": "----------------------------------------------MPNYKLLYFNMRGRAEIIRYIFAYLDIKYEDHRIEQADWPKIKPTLPFGKIPVLEVEGLTIHQSLAIARYLTKNTDLAGKTALEQCQADAVVDTLDDFMSLFPWA--EKDQDLKERMFNELLTHQAPRLLKDLDTYLGDKEWFIGN-YVTWADFYWD-ICSTTLLVLKPGLLDIYPKLVSLRNKVQAIPAISAWILKRPQTKL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O60760-1", "uniprot_id": "HPGDS_HUMAN", "id": "O60760-1", "name": "Hematopoietic prostaglandin D synthase", "aln": "----------------------------------------------MPNYKLTYFNMRGRAEIIRYIFAYLDIQYEDHRIEQADWPEIKSTLPFGKIPILEVDGLTLHQSLAIARYLTKNTDLAGNTEMEQCHVDAIVDTLDDFMSCFPWA--EKKQDVKEQMFNELLTYNAPHLMQDLDTYLGGREWLIGN-SVTWADFYWE-ICSTTLLVFKPDLLDNHPRLVTLRKKVQAIPAVANWIKRRPQTKL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P41043-1", "uniprot_id": "GSTS1_DROME", "id": "P41043-1", "name": "Glutathione S-transferase S1", "aln": "MADEAQAPPAEGAPPAEGEAPPPAEGAEGAVEGGEAAPPAEPAEPIKHSYTLFYFNVKALAEPLRYLFAYGNQEYEDVRVTRDEWPALKPTMPMGQMPVLEVDGKRVHQSISMARFLAKTVGLCGATPWEDLQIDIVVDTINDFRLKIAVVSYEPEDEIKEKKLVTLNAEVIPFYLEKLEQTVKDNDGHLALGKLTWADVYFAGITDYMNYMVKRDLLEPYPALRGVVDAVNALEPIKAWIEKRPVTEV", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .*.* ***::. ** :**:*** : :*** *: : :** :*.*:*:*::*:***:* :***:::**:*:*...*.* * *: : * :***::** :. . * .:::**: : * : * ::.*: : ..: :. :****.*: * . :.* .** :* * : . *:*: .: ** :** *::", "identical_positions": 68, "similar_positions": 72, "identity": "27.31%" }, { "cls_id": "homologset.agr.MGI:1859388", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZHH1-1", "uniprot_id": "DLL4_RAT", "id": "D3ZHH1-1", "name": "Delta-like protein 4", "aln": "MTPGSRSACRWALLLLAVLWPQQRAAGSGIFQLRLQEFANERGMLANGRPCEP-----------GCRTFFRICLKHYQATFSE-GPCTFGNVSTPVLGTNSFVIRDKNSGSGR---NPLQLPFNFTWPGTFSLNIQAWHTPGDDLRPETSPGNSLISQIIIQGSLAVGKNWKSDEQNNTLTRLRYSYRVVCSDNYYGDSCSRLCKKRDDHFGHYECQPDGSLSCLPGWTGKYCDQPICLSGCHEQNGYCSKPDECNCRPGWQGPLCNECIPHNGCRHGTCTIPWQCACDEGWGGLFCDQDLNYCTHHSPCKNGSTCSNSGPRGYTCTCLPGYTGEHCELELSKCAS--NPCRNGGSCKDH---ENSYHCLCPPGYYGQHCEHSTLTCADSPCFNGGSCRER----NQGASYACECPPNFTGSNCEKKVDRCTSNPCANGGQCLNRG----PS-------------------------------RTCRCRPGFTGTHCELHISDCARSPCAHGGTCHDLENGPVCTCPAGFSGRRCEVRITNDACASGPCFNGATCYTGLSPNNFVCNCPYGFVGSRCEFP--------------------VGLPPSFPWVAVSLGVGLVVLLVLLVMVAVAVRQLRLRRPDDDSREA-----MNNLSDFQKDN------LIPAAQLKNTNQKKELEVDCG-------------------------------------------LDKSNCG--------KLQNHTLDYNLAPGFLGRGSTPGKYPHSDKSLG----EKVPLRLHSEKPACR----------ISAICS----PRDSMYQSVCLISEERNECVIATEV-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9JI71-1", "uniprot_id": "DLL4_MOUSE", "id": "Q9JI71-1", "name": "Delta-like protein 4", "aln": "MTPASRSACRWALLLLAVLWPQQRAAGSGIFQLRLQEFVNQRGMLANGQSCEP-----------GCRTFFRICLKHFQATFSE-GPCTFGNVSTPVLGTNSFVVRDKNSGSGR---NPLQLPFNFTWPGTFSLNIQAWHTPGDDLRPETSPGNSLISQIIIQGSLAVGKIWRTDEQNDTLTRLSYSYRVICSDNYYGESCSRLCKKRDDHFGHYECQPDGSLSCLPGWTGKYCDQPICLSGCHEQNGYCSKPDECICRPGWQGRLCNECIPHNGCRHGTCSIPWQCACDEGWGGLFCDQDLNYCTHHSPCKNGSTCSNSGPKGYTCTCLPGYTGEHCELGLSKCAS--NPCRNGGSCKDQ---ENSYHCLCPPGYYGQHCEHSTLTCADSPCFNGGSCRER----NQGSSYACECPPNFTGSNCEKKVDRCTSNPCANGGQCQNRG----PS-------------------------------RTCRCRPGFTGTHCELHISDCARSPCAHGGTCHDLENGPVCTCPAGFSGRRCEVRITHDACASGPCFNGATCYTGLSPNNFVCNCPYGFVGSRCEFP--------------------VGLPPSFPWVAVSLGVGLVVLLVLLVMVVVAVRQLRLRRPDDESREA-----MNNLSDFQKDN------LIPAAQLKNTNQKKELEVDCG-------------------------------------------LDKSNCG--------KLQNHTLDYNLAPGLLGRGGMPGKYPHSDKSLG----EKVPLRLHSEKPECR----------ISAICS----PRDSMYQSVCLISEERNECVIATEV-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9NR61-1", "uniprot_id": "DLL4_HUMAN", "id": "Q9NR61-1", "name": "Delta-like protein 4", "aln": "MAAASRSASGWALLLLVALW-QQRAAGSGVFQLQLQEFINERGVLASGRPCEP-----------GCRTFFRVCLKHFQAVVSP-GPCTFGTVSTPVLGTNSFAVRDDSSGGGR---NPLQLPFNFTWPGTFSLIIEAWHAPGDDLRPEALPPDALISKIAIQGSLAVGQNWLLDEQTSTLTRLRYSYRVICSDNYYGDNCSRLCKKRNDHFGHYVCQPDGNLSCLPGWTGEYCQQPICLSGCHEQNGYCSKPAECLCRPGWQGRLCNECIPHNGCRHGTCSTPWQCTCDEGWGGLFCDQDLNYCTHHSPCKNGATCSNSGQRSYTCTCRPGYTGVDCELELSECDS--NPCRNGGSCKDQ---EDGYHCLCPPGYYGLHCEHSTLSCADSPCFNGGSCRER----NQGANYACECPPNFTGSNCEKKVDRCTSNPCANGGQCLNRG----PS-------------------------------RMCRCRPGFTGTYCELHVSDCARNPCAHGGTCHDLENGLMCTCPAGFSGRRCEVRTSIDACASSPCFNRATCYTDLSTDTFVCNCPYGFVGSRCEFP--------------------VGLPPSFPWVAVSLGVGLAVLLVLLGMVAVAVRQLRLRRPDDGSREA-----MNNLSDFQKDN------LIPAAQLKNTNQKKELEVDCG-------------------------------------------LDKSNCG--------KQQNHTLDYNLAPGPLGRGTMPGKFPHSDKSLG----EKAPLRLHSEKPECR----------ISAICS----PRDSMYQSVCLISEERNECVIATEV-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P10041-1", "uniprot_id": "DL_DROME", "id": "P10041-1", "name": "Neurogenic locus protein delta", "aln": "---MHWIKCLLTAFICFTVIVQVHSSGS--FELRLKYFSNDHGRDNEGRCCSGESDGATGKCLGSCKTRFRVCLKHYQATIDTTSQCTYGDVITPILGENSVNLTDAQRFQNKGFTNPIQFPFSFSWPGTFSLIVEAWHDTNNSGNARTN--KLLIQRLLVQQVLEVSSEWKTNKSESQYTSLEYDFRVTCDLNYYGSGCAKFCRPRDDSFGHSTCSETGEIICLTGWQGDYCHIPKCAKGCEH--GHCDKPNQCVCQLGWKGALCNECVLEPNCIHGTCNKPWTCICNEGWGGLYCNQDLNYCTNHRPCKNGGTCFNTGEGLYTCKCAPGYSGDDCENEIYSCDADVNPCQNGGTCIDEPHTKTGYKCHCANGWSGKMCEEKVLTCSDKPCHQGICRNVRPGLGSKGQGYQCECPIGYSGPNCDLQLDNCSPNPCINGGSCQPSGKCICPAGFSGTRCETNIDDCLGHQCENGGTCIDMVNQYRCQCVPGFHGTHCSSKVDLCLIRPCANGGTCLNLNNDYQCTCRAGFTGKDCSV--DIDECSSGPCHNGGTCMN--RVNSFECVCANGFRGKQCDEESYDSVTFDAHQYGATTQARADGLTNAQVVLIAVFSVAMPLVAVIAACVVFCMKRKRKRAQEKDDAEARKQNEQNAVATMHHNGSGVGVALASASLGGKTGSNSGLTFDGGNPNIIKNTWDKSVNNICASAAAAAAAAAAADECLMYGGYVASVADNNNANSDFCVAPLQRAKSQKQLNTDPTLMHRGSPAGSSAKGASGGGPGAAEGKRISVLGEGSYCSQRWPSLAAAGVAGACSSQLMAAASVAGSGAGTAQQQRSVVCGTPHM", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . : :: .: * :::** *:*:*: * *::* .*: *. .*:* **:****:**... . **:* * **:** **. : * . .: **:*:**.*:******* ::*** ..:. ...: . **.:: :* * *.. * ::. . * * *.:** *. ****..*:::*: *:* *** *. *.: **.** *.**. * * .**.. *:*.** :* *: **:* *****: . .* ****. ** * *:******:*:*******:* *****.** *:* ***.* ***:* .** : .* : ***:***:* *. : .*:* *. *: * **...*:*:*.**.:* . . * .:* .* **** .::*.**: ::*.*:.*** ***.* * *: *:* *** **:*. ::. * ***:**** :*:*. *** ***:*: *.* * *:*.**.* .** . :.* * *. ** *.:*: **. : : . :.*.: :: *: *...::: * * :. . ** * :: ::::. * .*: :*..:. * .* * *:.*.. : : : * * : ** .*. .:. .. * * : : .* . * ::. ** . *: * . ::::.. * .* ", "identical_positions": 259, "similar_positions": 221, "identity": "30.61%" }, { "cls_id": "homologset.agr.MGI:1859396", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9JJ25-1", "uniprot_id": "MEFV_RAT", "id": "Q9JJ25-1", "name": "Pyrin", "aln": "MANTRVDHLLNTLEELLPYELEKFKFKLHTTSLEKGHSRIPLSLVKMARPIKLTRLLLTYYGEEYAVRLTLQILRATNQRQLAEELHKATGPEHLTEENGVGGSVQSS--AENKDKGVKGSDVPGEDE---AQQNDDESDILPPIQAEVGKGPQKKSLAKRKDQRGPESLDSQTKPGARSAAPLYRRTLVTQSPGDKENRAGAQPQECQLCREAARSTAMSQGGERSRRLKCICLQERSD---PGVLKLPLTQKK-ENPQIQKLFRLKRKQEMAVSFVREATLNGRTTGTLEKGVGIPEHSMMLDEETSRNMSSKISLTREKRCTASWTENGNGGPETPETLGETVSSILCDSCSPKVLLSLGEKLAQTPEDPASLGQAASKGRSRDKVACPLCHTQ-GELPAKACVQSSCSCSVAP-GDPKASG-RHSICFQCQSSRAGKSCEAQSPQFLPQCPRHMKQVQLLFCEDHREPICLICRLSQEHQGHRVRPIEEAALQYKEQIRKQLERLREMRGYVEEHKLPADKKAEDFLKQTETQKQRISCPLEKLFQFLEQQEQLFVTWLQELVQTIGKVR-ETYYTQVS----LLDKLIGELEAKQDQPEWELMQ-DIGATLHRAETMTASELLGIPPGVKEKLHLLYQKSKSAEKNMQRFSEMLGSEMAFS------ASDVATREGCRPSTTKAQALIPTVHLK-----------CDGAHTQDFDVILCA-----------ELEAGGS------------EPQDYLHPSS----------------AQDTPELHEIHSQNNKRK--FKSFLKWKPSFSRTDRC-----LRTCW----------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9JJ26-1", "uniprot_id": "MEFV_MOUSE", "id": "Q9JJ26-1", "name": "Pyrin", "aln": "MAKTLGDHLLNTLEELLPYDFEKFKFKLQNTSLEKGHSKIPRGHMQMARPVKLASLLITYYGEEYAVRLTLQILRATNQRQLAEELRKATGTEHLIEENRVGGSVQSS--VENKAKSVKVPDVPEGDG---TQQNNDESDTLPSSQAEVGKGPQKKSLTKRKDQRGPESLDSQTKPWTRSTAPLYRRTQGTQSPGDKESTASAQLRRNVSSAGRLQGLYNNAPGRRESKKAEVYVYLPSGKKRPRSLEITTYSREGEPPNSEVLPTQEETRNGSLIRMRTATLNGRTTGALEKGTGIPEHSMVLDEKTFRNMSSKTSLIGEERCPTSWTENGNGSPETTESSGETAGSILSD---PEVPLSLCEKPAKTPEDPASLGQAACEGRSQDKAVCPLCHTQEGDLRGDTCVQSSCSCSIAP-GDPKASG-RCSICFQCQGLLARKSCEAQSPQSLPQCPRHMKQVLLLFCEDHREPICLICRLSLEHQGHRVRPIEEAALEYKEQIREQLERLREMRGYVEEHRLQGDKKTDDFLKQTEIQKQKISCPLEKLYQLLEKQEQLFVTWLQELSQTISKVR-ETYYTRVS----LLDEMIEELEAKQDQPEWDLMQ-DIGITLHRAKMMSASELLDTPPGVKEKLHLLYQKSKSVEKNMQCFSEMLSSEMAFS------ASDVAKWEGRQPSATQVQGLVPTVHLK-----------CDGAHTQDCDVVFYP-----------EREAGGS------------EPKDYLHPQP----------------AQDTPELHEIHSRNNKRK--FKSFLKWKPSFSRTDWR-----LRTCCYRDLDQAAAHP----------NLIFSMI------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O15553-2", "uniprot_id": "MEFV_HUMAN", "id": "O15553-2", "name": "Pyrin", "aln": "MAKTPSDHLLSTLEELVPYDFEKFKFKLQNTSVQKEHSRIPRSQIQRARPVKMATLLVTYYGEEYAVQLTLQVLRAINQRLLAEELHRAAIQEYSTQENGTDDSAASSSLGENKPRSLKTPDHPEGNEGNGPRPYGGGAASLRCSQPEAGRGLSRKPLSKRRE-KASEGLDAQGKPRTRSPALPGGRSPGP-CRALEGGQAEVRLRRNASSAGRLQGLAGGAPGQKECRPFEVYLP--SGKMRPRSLEVTISTGEKAPAN-------------------------------------PEILLTLEEKTAANLDSAT----EPRARP--TPDGGASADLKEGPG-------------------------NPE-------HSVTGRPPDTAASPRCHAQEGDPVDGTCVRDSCSFPEAVSGHPQASGSRSPGCPRCQDSHERKSPGSLSPQPLPQCKRHLKQVQLLFCEDHDEPICLICSLSQEHQGHRVRPIEEVALEHKKKIQKQLEHLKKLRKSGEEQRSYGEEKAVSFLKQTEALKQRVQRKLEQVYYFLEQQEHFFVASLEDVGQMVGQIR-KAYDTRVSQDIALLDALIGELEAKECQSEWELLQ-DIGDILHRAKTVPVPEKWTTPQEIKQKIQLLHQKSEFVEKSTKYFSETLRSEMEMFNVPELIGAQAHAVNVILDAETAYPNLIFSDDLKSVRLGNKWERLPDGPQRFDSCIIVLGSPSFLSGRRYWEVEVGDKTAWILGACKTSISRKGNMTLSPENGYWVVIMMKENEYQASSVPPTRLLIKEPPKRVGIFVDYRVGSISFYNVTARSHIYTFASCSFSGPLQPIFSPGTRDGGKNTAPLTICPVGGQGPD", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9PX13-1", "uniprot_id": "A0A8M9PX13_DANRE", "id": "A0A8M9PX13-1", "name": "", "aln": "---------------------MGEQTKPYKSILKDNTLKVPQISNQGQQSNSIGAVRWVLPDEEVQVHSSAPTIPYKSNSGFSTRSQQRQRQQGLKDLRSLDECIQFINRWKQQVAQVCKNEDDPGEG--------SSRPTKTDSRTERSLEESRKLILQWANELQSVDKLSKKQPWLKERIDLEEEDDKTKLDKSEGDEVQERITEWAKEIQSVSESCGMPGDELAQMLRLLGLRKKRLATLMPLLEFITWSLLKEESKG----------------------------------MVPHLWLSAKQRTWK---------------------------------------------------------------------AGISRYIPNSVWSWIVSAGADVSLDPMTNNPWLYVSED---------------------HKKIQEGLIEANLPYSSQRFDSLPCVLGWEGYMSGRHYWEVEFANNGYWRVGVTTASSKRHGRF--------------------------------------PMNPSSGYWVLWRSTRQFFACTNPETPLPQELVP-RRMGIYID----YEEGQISFYNADNKSHIYTFTG-HFREKLYPFFSLMDGRTLMTLWSPKEHSHF------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8M9PKM7-1", "uniprot_id": "A0A8M9PKM7_DANRE", "id": "A0A8M9PKM7-1", "name": "", "aln": "---------------------------MKKSILKANRYEAPEAG----LSNSIGAVTWTLPDEGLQAHSSVP-----------SKSSQSPRQKDLKDLRSLQECVKFITQWKQQVDQVCKPGANADEG--------PGASVLAEP---RSLEQCRKLILEWAQELRKVDSLFSEGTWRKER-DTSWEQKESQADSAK--HMEQKIMEWAKELQAVSERCGVMRQELAQFLKQLELKKRKILTLLPFLEFITWSLLKQDSQG----------------------------------VVPQLWLLSKHRTWK---------------------------------------------------------------------TETPKYIPNSVWRWIRSASVDISLDPMTNHPWLQLSDD---------------------KKKVQEALSETEVSFSKQRFDSWPCVLGWEGLTSGRYYWEVDIANKGYWRIGVTTASSKRHGRS--------------------------------------PMNPSEGFWTIWKSTRQFYACTKPETELPLTLVP-KKLGVYLD----YEEGQVSFYNVETRTHIFTFTA-NFRETLFPLFAPLDGRTLITLSTAEVNPETASL---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0AC58HIZ5-1", "uniprot_id": "A0AC58HIZ5_DANRE", "id": "A0AC58HIZ5-1", "name": "", "aln": "-----------------------------------------------MRSQSSDCFVLTR--------------------------KTGMHTNHMKDTNNNFNNSLLGAQKEKLIQAIKKIKHEIDEC--------YEAEKDAFVDALEVENRFEKIEREIRAEFQNLHRFLNEEEEADVERLKKERDKRVKILKDREKKIAMQGRDLEKAIETLN--CKLREDDSPKLLKEIKELLKRCEVNFVRPSPIDSEIFSSQFVG------------------------------------PIQYRIWK--------------------------------------------------------------------------HMKPSLYPNISLLTFDPETAHPLLTLSPERTAVTFEEG--------------------------KETGENAAERNPKRFHYYYCVMGSEGFTHGRHYWEVEVKGKTAWRVGVARADVHRGEMD--------------------------------------SSSTLNGLWTLSLRNGSITACTHPKPTPVLSYTPPIRIGVFLD----CDNEEVSFYNAVTMNPLFSFYTGTVLVPLYPFYNPCDTDEGKNCAPLSIFHPSL-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . . . . : : . :: : : .* : . . . : : . * . . . . . . :::. :: : :. : : . . . : : : . . :. : : :. : : . *. . ", "identical_positions": 3, "similar_positions": 55, "identity": "0.35%" }, { "cls_id": "homologset.agr.MGI:1859515", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q3V140-1", "uniprot_id": "ACRBP_MOUSE", "id": "Q3V140-1", "name": "Acrosin-binding protein", "aln": "MMNLAAGFLLMLLEVLLLPGTPLSAEES-PASTPGSPLSSTEYERFFALLTPTWKAETTCRLRATHGCRNPTLVQLDQYENHGLVPDGAVCSDLPYASWFESFCQFAQYRCSNHVYYAKRVRCSQPVSILSPNTLKEVESSAEVPPTSMTTPIVSHATATEHQAFQPWPERLNNNVEELLQSSLSLGGKDQQSSRRPGQEQR-KQEQIQEHKLEEAQEQEEQEEEEEEEEAKQEEGQGTEAGLESVSRLQSDSEPKFQSQSLSSNPSFFTPRVREVESAPLMMKNIQELIRSAQEMDEMNELYDDS--WRSQSTGSLQQLPHMETLMVLCYSIMENTCTMTPTAKAWSYMEEEILGFGDSVCDNLGRRHTAACPLCAFCSLKLEQCHSEASVLRQKCDASHKIPFISPLLSAQSISTGNQARIPDKGRFAGLEMYGGLSSEFWCNRLAMKGCEDDRVSNWLKAEFLSFQEGDFPTKICDTNYIQYPNYCSFKSQQCLLRNQNRKMSRMRCMLNERYNVLSLAKSEEVILRWSQEFSTLAIGQFG", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6AY33-1", "uniprot_id": "ACRBP_RAT", "id": "Q6AY33-1", "name": "Acrosin-binding protein", "aln": "-MKLAASFLLMLLEVLLLPETPLSAEEA-LASTPGSPLSSTEYERFFALLTPTWKAETTCRLRATHGCRNPTLVQLDQYENHGLVPDGAVCSDLPYASWFESFCQFAQYRCSNHVYYAKRVRCSQPVSILSPNTLKEVESSAEVPLTSVTTPIVSRATATEHQAFQPWPERLNNNVEELLQSSLSLGGKEQQSSRKLGLEQQHKQEQIQEHKLEEAQEQEEQEEEEEEEEAKQEEGQGTEEGLDSVSRLQSDSEPKFQSKSLSSNPSFFTPRVREVESAPLMMENIQELIRSAQEMDEMNELYDDS--WRSQSTGSLQQLPHTETLMVLCYSIMENTCTMTPTAKAWSYMEEEILGFGDSVCDNLGRRHTAACPLCAFCSLKLEQCHSEASVLRQQCDASHKIPFISPLLSAQSISTGNQAKIPEKGRFAGLEMYGGLSSEFWCNRLALKGCEDDRVANWLKAEFLSFQDGDLPTKICDTNYVQYPNYCSFKSQQCLLKNQNRKMSRMKCMLNEKYHVLSPAKGEEVILRWSQEFNTLTLGQFG", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8NEB7-1", "uniprot_id": "ACRBP_HUMAN", "id": "Q8NEB7-1", "name": "Acrosin-binding protein", "aln": "MRKPAAGFLPSLLKVLLLPLAPAAAQDSTQASTPGSPLSPTEYERFFALLTPTWKAETTCRLRATHGCRNPTLVQLDQYENHGLVPDGAVCSNLPYASWFESFCQFTHYRCSNHVYYAKRVLCSQPVSILSPNTLKEIEASAEVSPTTMTSPISPHFTVTERQTFQPWPERLSNNVEELLQSSLSLGGQEQAPEHKQEQGVEHRQEPTQEHKQEEGQKQEEQEEEQEEE-GKQEEGQGTKEGREAVSQLQTDSEPKFHSESLSSNPSSFAPRVREVESTPMIMENIQELIRSAQEIDEMNEIYDENSYWRNQNPGSLLQLPHTEALLVLCYSIVENTCIITPTAKAWKYMEEEILGFGKSVCDSLGRRHMSTCALCDFCSLKLEQCHSEASLQRQQCDTSHKTPFVSPLLASQSLSIGNQVGSPESGRFYGLDLYGGLHMDFWCARLATKGCEDVRVSGWLQTEFLSFQDGDFPTKICDTDYIQYPNYCSFKSQQCLMRNRNRKVSRMRCLQNETYSALSPGKSEDVVLRWSQEFSTLTLGQFG", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : **.** **:***** :* :*::: *********.****************************************************:*************::************* ***************:*:****. *::*:** .: *.**:*:********.***************::* ..:: . :** **** **.*:*******:*** .********: * ::**:**:******:*:******* *:********:*::*:***********:*****:**:. **.*..*** **** *:*:******:**** :*******.**********.****.***** ::*.** **************: **:**:*** **:****::**:* ***. *:.*** **::**** :*** *** ***** **:.**::******:**:*******:*:**************::*:***:***:*: ** * .** .*.*:*:*******.**::****", "identical_positions": 395, "similar_positions": 100, "identity": "72.61%" }, { "cls_id": "homologset.agr.MGI:1859516", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P62857-1", "uniprot_id": "RS28_HUMAN", "id": "P62857-1", "name": "Small ribosomal subunit protein eS28", "aln": "MDTSRVQPIKLARVTKVLGRTGSQGQCTQVRVEFMDDTSRSIIRNVKGPVREGDVLTLLESEREARRLR", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P62858-1", "uniprot_id": "RS28_MOUSE", "id": "P62858-1", "name": "Small ribosomal subunit protein eS28", "aln": "MDTSRVQPIKLARVTKVLGRTGSQGQCTQVRVEFMDDTSRSIIRNVKGPVREGDVLTLLESEREARRLR", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P62859-1", "uniprot_id": "RS28_RAT", "id": "P62859-1", "name": "Small ribosomal subunit protein eS28", "aln": "MDTSRVQPIKLARVTKVLGRTGSQGQCTQVRVEFMDDTSRSIIRNVKGPVREGDVLTLLESEREARRLR", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q6PBK3-1", "uniprot_id": "RS28_DANRE", "id": "Q6PBK3-1", "name": "Small ribosomal subunit protein eS28", "aln": "MDASRVQPIKLARVTKVLGRTGSQGQCTQVRVEFMDDSNRSIIRNVKGPVREGDVLTLLESEREARRLR", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9W334-1", "uniprot_id": "RS28_DROME", "id": "Q9W334-1", "name": "Small ribosomal subunit protein eS28", "aln": "MD----KPVVWARVMKVLGRTGSQGQCTQVKVEFLGEQNRQIIRNVKGPVREGDILTLLESEREARRLR", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VAB9-1", "uniprot_id": "Q9VAB9_DROME", "id": "Q9VAB9-1", "name": "Small ribosomal subunit protein eS28", "aln": "MD----KPQ-YARVVEILGRTGSQGQCTQVRVEFLGDQSRQIIRNVKGPVRVGDILSLLETEREARRLR", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q3E7X9-1", "uniprot_id": "RS28A_YEAST", "id": "Q3E7X9-1", "name": "Small ribosomal subunit protein eS28A", "aln": "MDN--KTPVTLAKVIKVLGRTGSRGGVTQVRVEFLEDTSRTIVRNVKGPVRENDILVLMESEREARRLR", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P0C0X0-1", "uniprot_id": "RS28B_YEAST", "id": "P0C0X0-1", "name": "Small ribosomal subunit protein eS28B", "aln": "MDS--KTPVTLAKVIKVLGRTGSRGGVTQVRVEFLEDTSRTIVRNVKGPVRENDILVLMESEREARRLR", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "** * *:* ::******:* ***:***: : .* *:******** .*:* *:*:********", "identical_positions": 40, "similar_positions": 13, "identity": "57.97%" }, { "cls_id": "homologset.agr.MGI:1859517", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O88178-1", "uniprot_id": "B3GT4_RAT", "id": "O88178-1", "name": "Beta-1,3-galactosyltransferase 4", "aln": "MPLSLFRRLLLAVLLLVIIWTLFGPSGLGEELLSLSLASLLPAPASPGPPLALPRLLIPNPQACGGSGPPPFLLILVCTAPEHLNQRNAIRGSWGAIREARGFRVQTLFLLGEPMGQ------QFADLASESAAQGDVLQASFQDSYRNLTLKTLTGLNWVNKYCPMARYILKTDDDVYVNVPELVSELIQRGGPSEQWQKGKEPQ-EETTAVHKEHKGQAVPLLYLGRVHWRVRPTRTPESRHHVSEELWPENWGPFPPYASGTGYVLSISAVQLILKVASRAPYLPLEDVFVGVSARRVGLAPTHCVKLAGATHYPLDRCCYGKFLLTSHKVDPWKMQEAWKLVRGLNGRRTEPFCSWLQGFLGTLRCRFIAWLNS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9Z0F0-1", "uniprot_id": "B3GT4_MOUSE", "id": "Q9Z0F0-1", "name": "Beta-1,3-galactosyltransferase 4", "aln": "MPLSLFRRVLLAVLLLVIIWTLFGPSGLGEELLSLSLASLLPAPASPGPPLALPRLLISNSHACGGSGPPPFLLILVCTAPEHLNQRNAIRASWGAIREARGFRVQTLFLLGKPRRQ------QLADLSSESAAHRDILQASFQDSYRNLTLKTLSGLNWVNKYCPMARYILKTDDDVYVNVPELVSELIQRGGPSEQWQKGKEAQ-EETTAIHEEHRGQAVPLLYLGRVHWRVRPTRTPESRHHVSEELWPENWGPFPPYASGTGYVLSISAVQLILKVASRAPPLPLEDVFVGVSARRGGLAPTHCVKLAGATHYPLDRCCYGKFLLTSHKVDPWQMQEAWKLVSGMNGERTAPFCSWLQGFLGTLRCRFIAWFSS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O96024-1", "uniprot_id": "B3GT4_HUMAN", "id": "O96024-1", "name": "Beta-1,3-galactosyltransferase 4", "aln": "MQLRLFRRLLLAALLLVIVWTLFGPSGLGEELLSLSLASLLPAPASPGPPLALPRLLIPNQEACSGPGAPPFLLILVCTAPENLNQRNAIRASWGGLREARGLRVQTLFLLGEPNAQHPVWGSQGSDLASESAAQGDILQAAFQDSYRNLTLKTLSGLNWAEKHCPMARYVLKTDDDVYVNVPELVSELVLRGGRWGQWERSTEPQREAEQEGGQVLHSEEVPLLYLGRVHWRVNPSRTPGGRHRVSEEQWPHTWGPFPPYASGTGYVLSASAVQLILKVASRAPLLPLEDVFVGVSARRGGLAPTQCVKLAGATHYPLDRCCYGKFLLTSHRLDPWKMQEAWKLVGGSDGERTAPFCSWFQGVLGILRCRAIAWLQS", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* * ****:***.*****:***************************************.* .**.*.*.*************:********.***.:*****:*********:* * * :**:*****: *:***:*************:****.:*:******:******************: *** **::..*.* * : :.: *************.*:*** .**:**** **..**************** ************** ************** *****:*************************::***:******** * :*.** *****:**.** **** ***:.*", "identical_positions": 291, "similar_positions": 50, "identity": "76.98%" }, { "cls_id": "homologset.agr.MGI:1859544", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q62746-1", "uniprot_id": "SYT6_RAT", "id": "Q62746-1", "name": "Synaptotagmin-6", "aln": "MSGVWGA-GGPRCQAALAVLASLCRARPPPLGLDVETCQSFELQPPEQSPSAADSGTSVSLLAVVVIVCGVALVAVFFFLFWKLCWMPWRNKEASSPSSANPASE--ILQSPSSRGN-----------MADKLKDPSA-LGFLEAAVKISHTSPDIPAEVQMSVKEHIMRHTK-LQRQTTEPASSTRHTSFKRHLPRQMH-VSSVDYGNELPPAAAEQP---TSIGRIKPELYKQKSVDGDE-AKSEAAKSCGKINFSLRYDYESETLIVRILKAFDLPAKDFCGSSDPYVKIYLLPDRKCKLQTRVHRKTLNPTFDENFHFPVPYEELADRKLHLSVFDFDRFSRHDMIGEVILDNLFEASDLSRETSIWKDIQYATSESVDLGEIMFSLCYLPTAGRLTLTVIKCRNLKAMDITGYSDPYVKVSLLCDGRRLKKKKTTIKKNTLNPVYNEAIIFDIPPENMDQVSLLISVMDYDRVGHNEIIGVCRVGISAEGLGRDHWNEMLAYPRKPIAHWHCLAEVKKSFKEGTPRL------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9R0N8-1", "uniprot_id": "SYT6_MOUSE", "id": "Q9R0N8-1", "name": "Synaptotagmin-6", "aln": "MSGVWGA-GGPRCQAALAVLASLCRARPPPLGLDVETCRSFELQSPEQSPSAADSGTSVSLLAVVVIVCGVALVAVFLFLFWKLCWMPWRKKEASSPSSANPASE--TLQSPSSRGN-----------MADKLKDPSA-LGFLEAAVKISHTSPDIPAEVQMSVKEHIMRHTK-LQRQTTEPASSTRHTSFKRHLPRQMH-VSSVDYGNELPPAAAEQP---TSIGRIKPELYKQKSVDGDD-AKSEAAKSCGKINFSLRYDYESETLIVRILKAFDLPAKDFCGSSDPYVKIYLLPDRKCKLQTRVHRKTLNPTFDENFHFPVPYEELADRKLHLSVFDFDRFSRHDMIGEVILDNLFEASDLSRETSIWKDIQYATSESVDLGEIMFSLCYLPTAGRLTLTVIKCRNLKAMDITGYSDPYVKVSLLCDGRRLKKKKTTIKKNTLNPIYNEAIIFDIPPENMDQVSLLISVMDYDRVGHNEIIGVCRVGINAEGLGRDHWNEMLAYPRKPIAHWHSLVEVKKSFKEGTPRL------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q5T7P8-1", "uniprot_id": "SYT6_HUMAN", "id": "Q5T7P8-1", "name": "Synaptotagmin-6", "aln": "MSGVWGA-GGPRCQEALAVLASLCRARPPPLGLDVETCRSFELQPPERSPSAAGAGTSVSLLAVVVIVCGVALVAVFLFLFWKLCWMPWRNKEASSPSSANPPLE--ALQSPSFRGN-----------MADKLKDPST-LGFLEAAVKISHTSPDIPAEVQMSVKEHIMRHTR-LQRQTTEPASSTRHTSFKRHLPRQMH-VSSVDYGNELPP-AAEQP---TSIGRIKPELYKQKSVDGED-AKSEATKSCGKINFSLRYDYETETLIVRILKAFDLPAKDFCGSSDPYVKIYLLPDRKCKLQTRVHRKTLNPTFDENFHFPVPYEELADRKLHLSVFDFDRFSRHDMIGEVILDNLFEASDLSRETSIWKDIQYATSESVDLGEIMFSLCYLPTAGRLTLTVIKCRNLKAMDITGYSDPYVKVSLLCDGRRLKKKKTTIKKNTLNPVYNEAIIFDIPPENMDQVSLLISVMDYDRVGHNEIIGVCRVGITAEGLGRDHWNEMLAYPRKPIAHWHSLVEVKKSFKEGNPRL------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M6YXX1-1", "uniprot_id": "A0A8M6YXX1_DANRE", "id": "A0A8M6YXX1-1", "name": "", "aln": "MSAAGKG-HDMICQKAVSLIVDLCTQDSP--RLDHNTCEEFLFLISSQEYNRNDSDVSVGLPVGVIIVCVLALLLLASFGSWKLCWIPWRNKALSSSSAALAPDDCPSPHIPSVLPS----PQPSEAMATEKEKYPMASMGFLEAAVKISHTSPDIPAEVQLSMREHFLRRTQRMQRQTTEPASSTRHSSFKRHLPRQMQ-VSSLDLGDDY-DVDEQP----TSIGRIKPELYKQMTTENDESANSKGGKNCGKINFSLRYDYENEMLLVKILKAFDLPAKDLCGSSDPYVKIYLLPDRKQKFQTRVHRKTLNPTFDESFQFPVPYDELAVRKLHLSVFDFDRFSRHDMIGEVILDNLFEVSDLSRETSIWRDIQYATSESVDLGEIMFSLCYLPTAGRLTLTVIKCRNLKAMDITGYSDPYVKVSLICDGRRLKKKKTTTKKNTLNPTYNEAIIFDIPPESMDQVSLHISVMDYDLVGHNEIIGVCRLGCGAEGLGRDHWNEMLAYPRKPIAHWHPLLESKKTEKEWKARTASFDSQGSCPSPKPPASP", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0AB32U4P6-1", "uniprot_id": "A0AB32U4P6_DANRE", "id": "A0AB32U4P6-1", "name": "", "aln": "MSAVATEEQDMFCEKAVALIVDLCLDDSP--LLDAKTCQDFLVLLTNKNPNISSTDISFSLLLLVFVVCGLALLGVISVATWKLCWVSWRSKVLSSSATALAPTQ-PEREQPREEGHGDYYPALRDIMAADKLKDPGN---FLEAAVKISHTSPDIPADVQLSMKDHLLRRTR-ISRQTTEPASSNRHSSFKKHLPRQMHHVTSLDRGSEFLDVEDHPSCTAASLGRIQPELYKQSTMEAEDSSKNDTDKSCGKINFSLKYDYEGELLLVTILKAFDLPAKDLCGSSDPYVKIYLLPDRKRKFQTRVHRKTLNPTFDETFQFPVPYEELGSRKLHLSVFDFDRFSRHDMIGEVILENLFEVSDLSRETSIWKDIQYATSESVDLGEIMFSLCYLPTAGRLTLTVIKCRNLKAMDITGYSDPYVKVSLICDGRRLKKKKTSIKKNTLNPTYNEAIIFDIPPENMDQVSLHISVMDYDLVGHNEIIGVCRVGIHAEGLGRDHWNEMLAYPRKPIAHWHPLVEPKKSEKEWKARTASFDSQGSCPSPRLPSSP", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "**.. . *: *::::..** .* ** :**..* . ..:. . .:. *..* *.:** :**: : . *****:.**.* **.::* .. : . * ::* * * *****************:**:*:::*::*:*: :.*********.**:***:******: *:*:* *.: . :*:***:****** : : :: ::.. *.********:**** * *:* ***********:***************** *:***************.*:*****:**. ************************:****.**********:*******************************************************:***********: ******* ************.****** ******* ***********:* ************************ * * **: ** ..* ", "identical_positions": 338, "similar_positions": 93, "identity": "61.45%" }, { "cls_id": "homologset.agr.MGI:1859545", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q62747-1", "uniprot_id": "SYT7_RAT", "id": "Q62747-1", "name": "Synaptotagmin-7", "aln": "MYRDPE-AASPGAPTRDVLLVSAIITVSLSVTIVLCGLCHWCQRKLGKRYKNSLETVGTPD----SGRGRGEKKAIK-------------------------------------------------------------------------------------------------------------------------------------------------------------------LPAGG----------------------------------------------------------------------------KAVNTAPVPGQTP------------------HDESDRRTEPRSSVSDLVNSLTSEMLMLSPGSEEDEAHEGCSRENLGRIQFSVGYNFQESTLTVKVMKAQELPAKDFSGTSDPFVKIYLLPDKKHKLETKVKRKNLNPHWNETFLFEGFPYEKVVQRILYLQVLDYDRFSRNDPIGEVSIPLNKVDLTQMQTFWKDLKPCSDGSGSRGELLLSLCYNPSANSIIVNIIKARNLKAMDIGGTSDPYVKVWLMYKDKRVEKKKTVTKKRNLNPIFNESFAFDIPTEKLRETTIIITVMDKDKLSRNDVIGKIYLSWK--SGPGEVKHWKDMIARPRQPVAQWHQLKA-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9R0N7-1", "uniprot_id": "SYT7_MOUSE", "id": "Q9R0N7-1", "name": "Synaptotagmin-7", "aln": "MYRDPE-AASPGAPTRDVLLVSAIITVSLSVTIVLCGLCHWCQRKLGKRYKNSLETVGTPD----SGRGRGEKKAIK-------------------------------------------------------------------------------------------------------------------------------------------------------------------LPAGG----------------------------------------------------------------------------KAVNTAPVPGQTP------------------HDESDRRTETRSSVSDLVNSLTSEMLMLSPGSEEDEAHEGCSRENLGRIQFSVGYNFQESTLTVKVMKAQELPAKDFSGTSDPFVKIYLLPDKKHKLETKVKRKNLNPHWNETFLFEGFPYEKVVQRVLYLQVLDYDRFSRNDPIGEVSIPLNKVDLTQMQTFWKDLKPCSDGSGSRGELLLSLCYNPSANSIIVNIIKARNLKAMDIGGTSDPYVKVWLMYKDKRVEKKKTVTKKRNLNPIFNESFAFDIPTEKLRETTIIITVMDKDKLSRNDVIGKIYLSWK--SGPGEVKHWKDMIARPRQPVAQWHQLKA-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O43581-1", "uniprot_id": "SYT7_HUMAN", "id": "O43581-1", "name": "Synaptotagmin-7", "aln": "MYRDPE-AASPGAPSRDVLLVSAIITVSLSVTVVLCGLCHWCQRKLGKRYKNSLETVGTPD----SGRGRSEKKAIK-------------------------------------------------------------------------------------------------------------------------------------------------------------------LPAGG----------------------------------------------------------------------------KAVNTAPVPGQTP------------------HDESDRRTEPRSSVSDLVNSLTSEMLMLSPGSEEDEAHEGCSRENLGRIQFSVGYNFQESTLTVKIMKAQELPAKDFSGTSDPFVKIYLLPDKKHKLETKVKRKNLNPHWNETFLFEGFPYEKVVQRILYLQVLDYDRFSRNDPIGEVSIPLNKVDLTQMQTFWKDLKPCSDGSGSRGELLLSLCYNPSANSIIVNIIKARNLKAMDIGGTSDPYVKVWLMYKDKRVEKKKTVTMKRNLNPIFNESFAFDIPTEKLRETTIIITVMDKDKLSRNDVIGKIYLSWK--SGPGEVKHWKDMIARPRQPVAQWHQLKA-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9PH33-1", "uniprot_id": "A0A8M9PH33_DANRE", "id": "A0A8M9PH33-1", "name": "Synaptotagmin-7", "aln": "MYLNREEEYSKGSISLSVLLVSLAVTVCGVWLVALCGVCGWCQRKLGKRNKPGVESVGSPD----SGRGRGEKKAIN--DLDRDFWNNNDSSSVQQRWSSYPPKEFVLNISPYAPYGDPRLTLNGTVPGGQKGAAGCVLGDGGGPSRSDSVRSMMTGGIKAGRWQTVQSRLHSGDFKNGNLSDHTLSSVETLDYVPSAGATPRPRTLLRQQSLQQPLIQAPPPNLASRPPISQSLGQLHTQPGGAGPGGGGGAGSRNSRGEPAQHRSAGAGGRGSGNPGSVDHMMGQIKKRGLDVKSFLEGKMVVLSLAIGLAEQDDFANLPDLQEVPASQETPEKSRNMGNKPANSPKGQPPD-----ADGHSSVSDLANSLTGDMVMLSPGSEDDD-HEGPVSEKLGRIQFSLGYSFQDTTLTVKILKGQDLPAKDFSGTSDPFVKIYLLPDRKHKLETKVKRKNLNPHWNETFLFEGFPYEKVRERTLYLQVLDYDRFSRNDPIGEVSIPLNKVELGQLKSFWKDLKPCSDGSGSRGDLLVSLCYNPTANTITVNIIKARNLKAMDIGGTSDPYVKVWLMHKDKRVEKKKTVTIKRCLNPVFNESFPFDVPAHVLRETTIIITVMDKDRLSRNDVIGKIYLSWK--SGPGEVKHWKDMLSRPRTNVAQWHALKA-", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0AB32TTK3-1", "uniprot_id": "A0AB32TTK3_DANRE", "id": "A0AB32TTK3-1", "name": "Synaptotagmin-7", "aln": "MHLNREDEDGKGSLSLSVFLVSVGLTVCVVWLVALCGVCGWCQRKLGMRNKPGVETAGTPDSVSVSGRGRGENKAINHNDLDRDFWNNNDSCSVQQRWSSYPPKEFLLNMSPYAPYGDPRLTPNGSLEKGEAGG-----GAVGGPSRSDSCIGAGTS--RSGRWQTLQSHLHSGSLRPSNFGDPSLSTTSTLEHIPSSAARPRP--LVRQQSLQQPLTHQPPPGPNDPPATSQSLGQLHTGPGGGGHRGGPRGVRGSPAGAGATRYRSGGGARSRSNPGSWDHMMGQIRTRGMDVKSFLEGKMVVLSLAIGLAEQDDFANLPDLQEAPADTETPPTDKRS-NKPGSSPKGQTPDESHRRTDANSSVSDLANSVTSDMLMLSPGSEEEE-HEGPVCEKLGRIQFSVGYSFQDSTLTVKILKGQDLPAKDFSGTSDPFVKLYLLPDKKHKLETKVKRKNLNPHWNETFLFEGFPYEKVVQRTLYLQVLDYDRFSRNDPIGEVSIPLNKVELVPMQTLWKELKPCSDGSGSRGDLLVSLCYNPTANIITVSIIKARNLKAMDIGGTSDPYVKVWLMNKDKRVEKKKTVVMKRCLNPVFNESFPFDVPAHVLRETTIVITVMDKDRLSRNDVIGKIYLSWK--SGPAEVKHWKDMMSHPRTAVAQWHALKA-", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9V4C4-1", "uniprot_id": "Q9V4C4_DROME", "id": "Q9V4C4-1", "name": "", "aln": "--------------MASIVLIACLAILGLIITIALFLAGGYLWWRHKRSQLQFIEPNEDEESS--SYSLRAAQDIVD----------------------------------------------------------------------------------------------------------------------------------------------------------------SGNPPTKP--------------------------------------------------------------------------QVPVAHAITTPLQNNINRKLNGFLSLRTPLIGGSGASQTKPQIISSVGNPGDGTTKDSANKSISMTDMYLDSTDPSENVGQIHFSLEYDFQNTTLILKVLQGKELPAKDLSGTSDPYVRVTLLPDKKHRLETKIKRRTLNPRWNETFYFEGFPIQKLQSRVLHLHVFDYDRFSRDDSIGEVFLPLCQVDFAGKQSFWKALKPP--AKDKCGELLSSLCYHPSNSILTLTLIKARNLKAKDINGKSDPYVKVWLQFGDKRVEKRKTPIFTCTLNPVFNESFSFNVPWEKIRECSLDVMVMDFDNIGRNELIGRILLAGKNGSGASETKHWQDMISKPRQTVVQWHRLKPE", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .:.*:: : :.* : : :*. : * *. :. :. * : .. :. . .: ***.: :. * : * . : .. *::*:*:**: *.**::** :*:::.::*****:******:*:: ****:**:****:**:.***:***** ***** :*: .* *:*:*:*******:*.**** :** :*:: :::** *** .... *:** ****:*: . : :.:******** **.*.********* ******:** . ***:*****.*::* . :** :: : *** *.:.**::**:* *: * **..*.***:**:::** *.*** **. ", "identical_positions": 159, "similar_positions": 116, "identity": "23.8%" }, { "cls_id": "homologset.agr.MGI:1859546", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O08625-1", "uniprot_id": "SYT10_RAT", "id": "O08625-1", "name": "Synaptotagmin-10", "aln": "------------------MSFRKEDGVSSLCQKALHIITELCFAGQVEWDKCSGIFPADRSGQGGGGTDISVSLLAVVVSFCGLALLVVSLFVFWKLCWPCWKSKLVAPNVSTLP---------------QSIS------------SAPTEVFETEEKK------EVEENEKPAPKAIEPAIKISHTSPDIPAEVQTALKEHLIKHARVQRQTTDPTSSSRHNSFRRHLPRQMNVSSVDFSMGTEPVLQRGETRTSIGRIKPELYKQKSVDSEGNRKDDVKTCGKLNFALQYDYENELLVVKIIKALDLPAKDFTGTSDPYVKIYLLPDRKKKFQTRVHRKTLNPLFDELFQFPVVYDQLSNRKLHFSIYDFDRFSRHDMIGEVILDNLFEVSDLSREATVWKDIHCATTESIDLGEIMFSLCYLPTAGRMTLTVIKCRNLKAMDITGSSDPYVKVSLMCEGRRLKKRKTTTKKNTLNPVYNEAIIFDIPPENVDQVSLCIAVMDYDRVGHNEVIGVCRTGLDAEGLGRDHWNEMLAYHRKPITHWHPLLELPGRATSFDSQGSCSSPRPPSTP", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9R0N4-1", "uniprot_id": "SYT10_MOUSE", "id": "Q9R0N4-1", "name": "Synaptotagmin-10", "aln": "------------------MSFRKEDGVSSLCQKALHIITELCFAGQVEWDKCSGIFPADRSGQGGGGTDISVSLLAVVVSFCGLALLVVSLFVFWKLCWPCWKSKLVAPNLSVLP---------------QSIS------------SAPTEVFETEEKK------EVEENEKPAPKAIEPAIKISHTSPDIPAEVQTALKEHLIKHARVQRQTTEPTSSSRHNSFRRHLPRQMNVSSVDFSVGTEPILQRGETRTSIGRIKPELYKQKSVDSEGNRKDDVKTCGKLNFALQYDYENELLVVKIIKALDLPAKDFTGTSDPYVKIYLLPDRKKKFQTRVHRKTLNPLFDELFQFPVVYDQLSNRKLHFSIYDFDRFSRHDMIGEVILDNLFEVSDLSREATVWKDIHCATTESIDLGEIMFSLCYLPTAGRMTLTVIKCRNLKAMDITGSSDPYVKVSLMCEGRRLKKRKTTTKKNTLNPVYNEAIIFDIPPENVDQVSLCIAVMDYDRVGHNEVIGVCRTGLDAEGLGRDHWNEMLAYHRKPITHWHPLLELPGRATSFDSQGSCSSPRPPSTP", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6XYQ8-1", "uniprot_id": "SYT10_HUMAN", "id": "Q6XYQ8-1", "name": "Synaptotagmin-10", "aln": "------------------MSFHKEDGVNSLCQKALHIVTELCFAGQVEWEKCSGIFPRDRGSQGGSSTDISVSLLAVVVSFCGLALLVVSLFVFWKLCWPCWKSKPVTSNITTLP---------------QSIS------------SAPTEVFETEEKK------EIKENEKPAVKAIEPAIKISHTSPDIPAEVQTALKEHLIKHARVQRQITEPTSSTRHSSFRRHLPRQMQVSSVDFSMGTEPVLQRGETTTSIGRIKPELYKQKSVDSEGNQNEDVKICGKLNFTLQYDYENELLVVKIIKALDLPAKDFTGTSDPYVKMYLLPDRKKKFQTRVHRKTLNPLFDETFQFPVAYDQLSNRKLHFSVYDFDRFSRHDMIGEVILDNLFEVSDLSREATVWKDIHCATTESIDLGEIMFSLCYLPTAGRMTLTVIKCRNLKAMDITGSSDPYVKVSLMCEGRRLKKRKTTTKKNTLNPVYNEAIIFDIPPENVDQVSLSIAVMDYDRVGHNEVIGVCRTGLDAEGLGRDHWNEMLAYHRKPITHWHPLLELPGRATSFDSQGSCPSPKPPSTP", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M6Z5Z8-1", "uniprot_id": "A0A8M6Z5Z8_DANRE", "id": "A0A8M6Z5Z8-1", "name": "", "aln": "MNSRPHASSNIQWINRKDMNVRTEDGIS-LCQRALQIVTELCLAGHVDREKCADIFPLESN-----IPDISVSLLAVVVGFCGLALLVVSLFVFWKLCWPIWRSKAFTSNADSCPPGVLLEAPPAPPPVSRSVSPYAEAKAVGVAGRQPSQIQHEDEEDKKWKVPEVKVNGRSSVKILEAAMKISQTSPDIPAEVQQALRDRLSKQAKIQRQTTEPTSSSRHNSFRRHLPRQMNVTSVDFTMDTLPVRQ--SSAVSIGRIKPELYKQKSVDSEEGTKEPVETCGKLSFALSYDYEEQALVVRILKALDLPAKDFTGTSDPYVKIYLLPERKKKFQTRVHRKTLNPTFDEDFRFPVEYSELCNRKLHFSVYDFDRFTSHDMIGEVVVDNLFELSDLSREAVVWKDILAATTESVDLGEIMYSLCYLPTAGRMTLTVIKCRNLKAMDITGYSDPYVKVALICDGRRLKKRKTTTKKNTLNPVYNEAIIFDIPPENVEQVSLSITVMDYDRVGHNEVIGVCRAGPDAEGLGRDHWNEMLAYPRKPITHWHALCEWPGRASSFESQGSCPSPKPPQTP", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *..:.***:. ***:**:*:****:**:*: :**:.*** : . .***********.******************** *:** .:.* * :*:* *::: . :*:. *:: * :.: * :*.*:***:********** **:::* *:*::*** *:****:**.**********:*:****::.* *: * .: .****************** . :: *: ****.*:*.****:: ***:*:*******************:****:**************** *** *:*** *.:*.*******:******: *******::*****:*******.***** .*****:******:**************************** *******:*:*:*********************************:****.*:*****************:* **************** ********.* * ****:**:*****.**:**.**", "identical_positions": 378, "similar_positions": 98, "identity": "65.85%" }, { "cls_id": "homologset.agr.MGI:1859547", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O08835-1", "uniprot_id": "SYT11_RAT", "id": "O08835-1", "name": "Synaptotagmin-11", "aln": "MAEITNIRPSFDVSPVAAGLIGASVLVVCVSVTVFVWTCCHQQAEKKHKTPPYKFIHMLKGISIYPETLSNKKKIIKVRRDKDGSHRESGRGNLLVN-AESGLLSHDRDPRGPSPASCIDQLPIKRDYGEELRSPMTSLTPGESKPTSPSSPEEDVMLGSLTFSVDYNFPKKALVVTIQEAHGLPVMDGQTQGSDPYIKMTILPDKRHRVKTRVLRKTLDPVFDETFTFYGIPYSQLQDLVLHFLVLSFDRFSRDDVIGEVMVPLAGVDPSTGKVQLTRDIIKRNIQKCISRGELQVSLSYQPVAQRMTVVVLKARHLPKMDITGLSGNPYVKVNVYYGRKRIAKKKTHVKKCTLNPIFNESFIYDIPTDLLPDISIEFLVIDFDRTTKNEVVGRLILGAHSVTTSGAEHWREVCESPRKPVAKWHSLSEY", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9R0N3-1", "uniprot_id": "SYT11_MOUSE", "id": "Q9R0N3-1", "name": "Synaptotagmin-11", "aln": "MAEITNIRPSFDVSPVAAGLIGASVLVVCVSVTVFVWTCCHQQAEKKHKTPPYKFIHMLKGISIYPETLSNKKKIIKVRRDKDGPRRESGRGNLLIN-AESGLLSHDKDPRGPSPASCMDQLPIKRDYGEELRSPMTSLTPGESKATSPSSPEEDVMLGSLTFSVDYNFPKKALVVTIQEAHGLPVMDDQTQGSDPYIKMTILPDKRHRVKTRVLRKTLDPVFDETFTFYGIPYSQLQDLVLHFLVLSFDRFSRDDVIGEVMVPLAGVDPSTGKVQLTRDIIKRNIQKCISRGELQVSLSYQPVAQRMTVVVLKARHLPKMDITGLSGNPYVKVNVYYGRKRIAKKKTHVKKCTLNPVFNESFIYDIPTDLLPDISIEFLVIDFDRTTKNEVVGRLILGAHSVTTSGAEHWREVCESPRKPIAKWHSLSEY", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9BT88-1", "uniprot_id": "SYT11_HUMAN", "id": "Q9BT88-1", "name": "Synaptotagmin-11", "aln": "MAEITNIRPSFDVSPVVAGLIGASVLVVCVSVTVFVWSCCHQQAEKKQKNPPYKFIHMLKGISIYPETLSNKKKIIKVRRDKDGPGREGGRRNLLVDAAEAGLLSRDKDPRGPSSGSCIDQLPIKMDYGEELRSPITSLTPGESKTTSPSSPEEDVMLGSLTFSVDYNFPKKALVVTIQEAHGLPVMDDQTQGSDPYIKMTILPDKRHRVKTRVLRKTLDPVFDETFTFYGIPYSQLQDLVLHFLVLSFDRFSRDDVIGEVMVPLAGVDPSTGKVQLTRDIIKRNIQKCISRGELQVSLSYQPVAQRMTVVVLKARHLPKMDITGLSGNPYVKVNVYYGRKRIAKKKTHVKKCTLNPIFNESFIYDIPTDLLPDISIEFLVIDFDRTTKNEVVGRLILGAHSVTASGAEHWREVCESPRKPVAKWHSLSEY", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "****************.********************:*********:*.**********************************. **.** ***:: **:****:*:******..**:****** *********:*********.******************************************.************************************************************************************************************************************************************************:**********************************************:****************:*********", "identical_positions": 407, "similar_positions": 20, "identity": "94.43%" }, { "cls_id": "homologset.agr.MGI:1859549", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O70355-1", "uniprot_id": "BTNL2_MOUSE", "id": "O70355-1", "name": "Butyrophilin-like protein 2", "aln": "MVDCPRYSLSGVAASFLFVLLTIKHPDDFRVVGPNLPILAKVGEDALLTCQLLPKRTTAHMEVRWYRSDPDMPVIMYRDGAEVTGLPMEGYGGRAEWMEDSTEEGSVALKIRQVQPSDDGQYWCRFQEGDYWRETSVLLQVAALGSSPNIHVEGLGEGEVQLVCTSRGWFPEPEVHWEGIWGEKLMSFSENHVPGEDGLFYVEDTLMVRNDSVETISCFIYSHGLRETQEATIALSERLQTELASVSVIGHSQPSPVQVGENIELTCHLSPQTDAQNLEVRWLRSRYYPAVHVYANGTHVAGEQMVEYKGRTSLVTDAIHEGKLTLQIHNARTSDEGQYRCLFGKDGVYQEARVDVQVMAVGSTPRITREVLKDGGMQLRCTSDGWFPRPHVQWRDRDGKTMPSFSEAFQQGSQELFQVETLLLVTNGSMVNVTCSISLP-LGQEKTARFPLSG------W---------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6MG97-1", "uniprot_id": "BTNL2_RAT", "id": "Q6MG97-1", "name": "Butyrophilin-like protein 2", "aln": "MVDFPGYSLSGVAASFLFVLLTMKHPDDFRVVGPALPILANVGEDALLTCRLLPKRTTARMEVRWYRSDPDTPVMLYRDGAEVPGLAMEGYRGRVEWMEDSTEEGSVALKIRQVQPGDDGQYWCRIQEGDYWREASVLLQVAALGSSPNIHVEGPGEEGVQLVCTSRGWFPEPEVYWEGIRGEKLMSLSENHVYGEDGLFSVEDTLVVRNDSVETISCFIYNRGLREPQEATIALPEKLQTELASSRVIGPSQAIPVRVGETIELTCQLSPQTDAQSLEVRWLRARYYPVVHVYTNGAHEAGEQMAEYRGRTSLVTDAIHEGKLTLQIHNARTSDEGQYRCLFGKDGVYQEARVDVQVMAVGSTPQITREVLKDGGTQLRCTSDGWFPRPHVQWRDRDGRTLPSFSEAFRQGSQELFQVETLLLVTNGSMVNVTCSISLP-LGEEKTARFPLSG------W---------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9UIR0-7", "uniprot_id": "BTNL2_HUMAN", "id": "Q9UIR0-7", "name": "Butyrophilin-like protein 2", "aln": "MVDFPGYNLSGAVASFLFILLTMKQSEDFRVIGPAHPILAGVGEDALLTCQLLPKRTTMHVEVRWYRSEPSTPVFVHRDGVEVTEMQMEEYRGWVEWIENGIAKGNVALKIHNIQPSDNGQYWCHFQDGNYCGETSLLLKVAGLGSAPSIHMEGPGESGVQLVCTARGWFPEPQVYWEDIRGEKLLAVSEHRIQDKDGLFYAEATLVVRNASAESVSCLVHNPVLTEEKGSVISLPEKLQTELASLKVNGPSQPILVRVGEDIQLTCYLSPKANAQSMEVRWDRSHRYPAVHVYMDGDHVAGEQMAEYRGRTVLVSDAIDEGRLTLQILSARPSDDGQYRCLFEKDDVYQEASLDLKVVSLGSSPLITVEGQEDGEMQPMCSSDGWFPQPHVPWRDMEGKTIPSSSQALTQGSHGLFHVQTLLRVTNISAVDVTCSISIPFLGEEKIATFSLSESRMTFLWKTLLVWGLLLAVAVGLPRKRS", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*** * *.***..*****:***:*:.:****:** **** *********:******* ::*******:*. **:::***.**. : ** * * .**:*:. :*.*****:::**.*:*****::*:*:* *:*:**:**.***:*.**:** ** ******:*******:*:**.* ****::.**::: .:**** .* **:*** *.*::**:::. * * : :.*:*.*:******* * * **. *:*** *:*** ***:::**.:**** *:: **.**** :* * *****.**:*** **:***.**:***** .**.**:******* **.***** :*::*:::**:* ** * :** * *:******:*** *** :*:*:** *:*: ***: **:*:*** *** * *:******:* **:** * *.** * ", "identical_positions": 277, "similar_positions": 112, "identity": "57.47%" }, { "cls_id": "homologset.agr.MGI:1859553", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0ABK0LV49-1", "uniprot_id": "A0ABK0LV49_RAT", "id": "A0ABK0LV49-1", "name": "Leucine-rich repeat-containing protein 6", "aln": "MFRSLPNVQGLLLVNVGVTEDLIRRNAEHNECVIFSLEELSLHQQEIERLEHIDKWCRDLKILYLQNNLIAKIENVSKLKKLEYLNLALNNIERIENLEGCEWLTKLDLTVNFIGELSSIKTLTHNIHLRELFLVGNPCADFDGYREFVVVTLQQLKWLDGKEIERSERIQALQNYAAVEQQIREQEKAYCLRRAKEKEEAQRKLEEENESEDKKKSSPGFDGDCYTDIHADCPSAMENKDHLQVPETQEQQHSTKKSDEIEDDLAFWNKPSLFTPESRLETLRHMEKQRKAQDKLSEKKKRVKPPRTLITEDGKVLNVNEAKLDFSLKDDEKHNQIILDLAVYRYMDTSLIEVDVQPTYVRVMVKGKPFQLALSAEVQPDSSSAKRSQTTGHLLICMP--KVGEMITG-QQTPMSVKTASESSKEQTKPRRKQVERLEVDP-SKHSCPDVSTIVQERKHKPKRMESQPQVEPSEAEPDFDDNPEVPPLI", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O88978-1", "uniprot_id": "DAA11_MOUSE", "id": "O88978-1", "name": "Dynein axonemal assembly factor 11", "aln": "MGR--------------ITEDLIRRNAEHNDCVIFSLEELSLHQQEIERLEHIDKWCRDLKILYLQNNLIGKIENVSKLKKLEYLNLALNNIERIENLEGCEWLTKLDLTVNFIGELSSVKTLTHNIHLKELFLMGNPCADFDGYRQFVVVTLQQLKWLDGKEIERSERIQALQNYTSVEQQIREQEKAYCLRRAKEKEEAQRKLEEENESEDKKKSSTGFDGHWYTDIHTACPSATENQDYPQVPETQEEQHNTKESDDIEDDLAFWNKPSLFTPESRLETLRHMEKQRKAQDKLSEKKKKAKPPRTLITEDGKVLNVNEAKLDFSLKDDEKHNQIILDLAVYRYMDTSLIEVDVQPTYVRVMVKGKPFQLALSTEVQPDRSSAKRSQTTGHLLICMP--KVGEMITGGQRTPTSVKTTSTSSREQTNPRKKQIERLEVDP-SKHSCPDVSTIVQEKRHRPKRMESQPRDEPSEEDPDFEDNPEVPPLI", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q86X45-1", "uniprot_id": "DAA11_HUMAN", "id": "Q86X45-1", "name": "Dynein axonemal assembly factor 11", "aln": "MGW--------------ITEDLIRRNAEHNDCVIFSLEELSLHQQEIERLEHIDKWCRDLKILYLQNNLIGKIENVSKLKKLEYLNLALNNIEKIENLEGCEELAKLDLTVNFIGELSSIKNLQHNIHLKELFLMGNPCASFDHYREFVVATLPQLKWLDGKEIEPSERIKALQDYSVIEPQIREQEKDHCLKRAKLKEEAQRKHQEEDKNEDKR-SNAGFDGRWYTDIN-ATLSSLESKDHLQAPDT--EEHNTKKLDNSEDDLEFWNKPCLFTPESRLETLRHMEKQRKKQEKLSEKKKKVKPPRTLITEDGKALNVNEPKIDFSLKDNEK--QIILDLAVYRYMDTSLIDVDVQPTYVRVMIKGKPFQLVLPAEVKPDSSSAKRSQTTGHLVICMP--KVGEVITGGQRAFKSMKTTSDRSREQTNTRSKHMEKLEVDP-SKHSFPDVTNIVQEKKHTPRRR-PEPKIIPSEEDPTFEDNPEVPPLI", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "B3DH20-1", "uniprot_id": "DAA11_DANRE", "id": "B3DH20-1", "name": "Dynein axonemal assembly factor 11", "aln": "MVR--------------ISEDLIRRRAEHNNGEIFSLEELSLHQQDIQRIEHIHKWCRDLKILYLQNNLIPKIENVGRLKKLEYLNLALNNIEVIENLEGCESLQKLDLTVNFVGRLSSVETLKHNLHLKELYLVGNPCAEYQGYRQYVVATVPQLQSLDGKEISRAERIQALQELDAVRTRVLQQETKYLEEREKQKSNAN-EHPEINQS----------------------LSESQN-GTQQYPESSSKTHTEAE----DEEREFWEKPCPFTPESRLEAHRHLEEKRRANEKEKEKPK-TKTPRTLITPDGRVLNVNEPKLDFSLFEDEN-NCLLLDLHVYRHMDSSLLDVDVQPMYVRVTVKGKVFQLVLPAEVKPDSSSAQRSQTTGHLLLILP--LANEDVKPKKRTIRPTSVTSNQNNKKDTRAAPRRELLEVDPGLAGSLANIVPKGQESSHNPQRCGLEER----PVSKDFVDDPEVPPLM", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VR52-1", "uniprot_id": "TILB_DROME", "id": "Q9VR52-1", "name": "Protein tilB", "aln": "MVL--------------ITEELVRKKSEHNERLISTLEEISLHQEDIEVIEHIQNWCRDLKILLLQSNLIARLENLHKLKRLEYLNVAINNIERVENLEGCESLSKLDLTLNFIRELTSVESLCGNYNLRELVLIGNPCVDYPHYRDYVVATLPQLNSLDCVEITPSERLRALRELSKNRSIIVQKQVEQDIERDEQR------------------------------------------IRVAKQQSALAEHCAGIEDEEERIKAFWQAKSEHCPEIRTEIARQHRLGRERHETKSPLDP-LKPQRNLFAPCGRPYNLNQAKLPFKFRDEAD--HYLLQLEVYRHLDTSLIDVDVQTTYTRVTVKKKIFQIAYSEEVKPDESTVQRSQITGHLVVNLKKLKVNELLIAKKSPTKSPAAPFDAGKKDGKP----------EEAFHGGVVDISNICAP--------------------------EDLPDLI", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* ::*:*:*:.:***: * :***:****::*: :***.:******** **.*** ::**: :**:*****:*:**** :******* * *****:**: .*:*::.* * :*:** *:****..: **::**.*: **: ** ** :**::**:: . : ::: .* : : :: * : **: . . ** * * *: . *. ::. . *. *.*:: *: *:*:.*: *.: :: . :*:* ***::*:**::****. *.** :* * **:. . **:** *:.:*** ****:: : ..* : : . . .. ..:. . : . :: ::* *:", "identical_positions": 140, "similar_positions": 123, "identity": "28.57%" }, { "cls_id": "homologset.agr.MGI:1859555", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P11654-1", "uniprot_id": "PO210_RAT", "id": "P11654-1", "name": "Nuclear pore membrane glycoprotein 210", "aln": "MARASLIQPGLWALLLLQAVGPAVAAKLNIPKVLLPFTRATRVNFTLEASEG-CYRWSSTRPEVASIEPLGSSEQQCSQKAVVQARLTQPARLTSIIFAEDITTGQVLRCDAIVDLIHGIQIVSTTRELYLEDSPLELKIQALDSEGNTFSTLAGLVFDWTIVKDTEANGFSDSHNALRILTFLESTY-IPPSYISEMEKAAKQGDTILVSGMKTGSSKLKARIQEAVYKNVRPAEVRLLILENILLNPAYDVYLLVGTSIHYKVQKIRQGKITELSMPSDQYELQLQNSIPDPQGDPARPVAVLTQDTSRVTAMQMGQSNLVLGHRSIR-MQGASRLPNSTIYVVEAGYLGFTVHPGDRWVLETGHLYAVTIEVFDRSSNKVYPSDNIRIEAVFPAEFFEVLSSSQNGSYHHVRAIQSGQTTISASLTSVVDQDGGVHVLQVPVWNQQEVDIHIPITLYPSILTFPWQPKTGAYQYT-----IKAHGGSGNFTWSSSSYMVATVTVKGVMTTGGDTGLSVIRAHDVQNPLHFGEMKVYVIEPSSMEFAPCQVEARVGHTLELPLTISGLMPGGSSEVVTLSDCSHFDLVVEVENQGVFQPLPGRLPPGPEHCSGVKVRADAQGSTTLLVSYTHGHVHLGAKITLAAYLPLKAVDPSS-VAVVTLGSSKEMLFEGGPRPWVLEPSKFFRNVTSEDTGSISLSLLGPPASRNYQQHRVLVTCQALGEQVIALSVGNRPSLSNPFPAVEPTVVKSVCAPPSRLTLMPVYALPQLDLSCPLLQQNKQVVPVSSHRNPLLDLGAYDQQGRRFDNFSSLSIQWESFRPLLASIEVDQPMQLVSQDDGNGQKKLHG--LQTVSVHEASGTTAISATATGYQQSHLSAAGVKQLRDPLVP------------VSASIELILVEDVRVSPEEVTIYNHPGVQVELHITEGSGYFFLNTSTQDIINVAYQDTRGVAMVHPLFPGSSTVMVHDLCLTFPAPAKATIHVSDIQELYVRVVDKVEIGKAVKAYVRVLDFYKKPFLAKYFTFMDLKLRAASQIITLVTLDEALDNYTATFLVHGVAIGQTSLSASVTDKSGQ---RVSSTAQQIEVFPPFRLIPRKVTLIIGAMIQITSEGGPQPQSNILFSINNESVAAVSSAGLVRGLMVGNGSVLGVVQAVDAETGKVIIVSQDHVEVEVLQLQAVRIRAPITRMRTGTQMPVYVTGITSNQSPFSFGNAVPGLTFHWSVTKRDVLDLRGRHHEVSIRLSPQYNFAMNVHGRVKGRTGLRVVVKALDPTAGQLHGLGKELSDEIQIQVFEKLRLLNP-EVEAEQILMSPNSFIKLQTNRDGAAILSYRVLDGPEKAPIVHIDEKGFLVSGSGIGVSTLEVIAQEPFGTNQTVLVAVKVSPISYLRISMSPVLHTQHKEVLTALPLGMTVTFTVHFHDSSGDIFHAHNSDLN-----FATNRDDFVQIGKGATNNTCIIRTVS--VGLTLLHVWDVEHLGLSDFVPLPVLQAITPELSG-AVVVGDILCLASVLISLGGVSGTWSSSAGNVLYVDPKTGVAIARDA--------GPVTVYYEIAGHLKTFKEIVVVTPQKIVARRLHATQTSIQEATASKVTVSVGDRSSNLLGECSSAQREAIEALHPESLISCQLQFKQDVFDFPARDIFSVEPGFDTALGQYLCSVTMHRLTDKQLKHLNMKKTSLAVTASMPSSRTSVEKVGAEVPFSPGLYANQAEILLSNHYPSSEVKIFGAVEILENLEVRSGSPAVLASVKEKSFGLPSFITYTVGVLDPTAGSQGPLSTALTFSSPATNQAITIPVTVAFVLDRRG-------PGPYGASLLSHFLDSYQVMFFTFFALLAGTAVTIIAYHTVCAPRE-------LASPLALTPHASPQHSPHYLASS-PTAFNTLPSDRKASPPSGLWSPAYASH----------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9QY81-1", "uniprot_id": "PO210_MOUSE", "id": "Q9QY81-1", "name": "Nuclear pore membrane glycoprotein 210", "aln": "MARASLVQPALWALLLLQVVGPAAAAKLNIPKVLLPFTRATRVNFTLEASEG-CYRWSSTRPEVASIEPLGSSEQQCSQKAVVQARLTQPARLTSIIFAEDITTGQVLRCDAIVDLIHGIQIVSTTRELYLEDSPLELKIQALDSEGNTFSTLAGLVFDWTIVKDTEANGFSDSHNALRILTFLESTY-IPPSYISEMEKAAKQGDTILVSGMKTGSSKLKARIQEAVYKNVRPAEVRLLILENILLNPAYDVYLLVGTSIHYKVQKIRQGKITELSMPSDQYELQLQNSIPDPQGDPARPVAILTQDTSRVTAMQMGQSNLVLGHRSIR-MQGASRLPNSTIYVVEAGYLGFTVYPGDRWVLETGHLYAITIEVFDRSSNKVYPSDNIRIEAVLPAEFFEVLSSSQNGSYHHIRAIQSGQTAISATLTSVVDQDGGVHVLQVPVWNQQEVDIHIPITLYPSILTFPWQPKTGAYQYT-----IKAHGGSGNFSWSSSSSMVATVTVKGVMTTSGDTGLSVIRAHDVQNPLHFGEMKVYVIEPSSMEFAPCQVEARVGHTLELPLTISGFMPGGGSEVVTLSDCSHFDLVVEVENQGVFQPLPGRLPPGPEHCSGVKVKADAQGSTTLLVSYTHGHVHLDAKITLAAYLPLKAVDPSS-VAVVTLGSSKEMLFEGGPRPWVLEPSKFFRNVTSEDTGSISLSLLGPPASRNYQQHRVLMTCQALGEQVIALSVGNRPSLSNPFPAVEPTVVKSICAPPSRLTLMPVYALPQLDLSCPLLQQNKQVVPVSSHRNPLLDLGAYDQQGRRFDNFSSLSIQWESSRPLLASIELDQPMQLVSQDDGNGQKKLHG--LQTVSVHEASGTTAISATATGYQQSHLSEARVKQPHDPLVP------------VSASIELILVEDVRVSPEEMTIYNHPGVQVELYITEGSGYFFLNTSTQDIIKVAYQDTRGVALVHPLLPGSSTVMVHDLCLAFPAPAKAIIHVSDIQELYVRVVDKVEIGKAVKAYVRVLDFYKKPFLAKYFTFMDLKLQAASQIITLVTLDEALDNYTATFLVHGVAIGQTSLSASVTDKSGQ---RVSSTPQQIEVFPPFRLIPRKVTLIIGAMMQITSEGGPQPQSNILFSINNESVAAVSSSGLVRGLMVGNGSVLGVVQAVDAETGKVIIVSQDLVEVEVLQLQAVRIRAPITRMRTGTQMPVFVTGITSNQSPFSFGNAVPGLTFHWSVTKRDVLDLRGRHHEVSIRLPPQYNFAMNVYGRVKGRTGLRVVVKALDPTAGQLHGLGKELSDEIQIQVFEKLRLLNP-EIEAEQILMSPNSFIKLQTNRDGAAILSYRVLDGPEKAPIVHTDEKGFLVSGSGIGVSTLEVIAQEPFGTNQTILVAVKVSPVSYLRISMSPVLHTQHKEALTALPLGMTVTFIVHFHDSSGDIFHAHNSVLN-----FATNRDDFVQIGKGATNNTCIIRTVS--VGLTLLHVWDVEHLGLSDFVPLPVLQAITPELSG-AVVVGDILCLASVLTSLGGVSGTWSSSASHVLYVDPKTGVAIARDA--------GSVTVYYEIAGQLKTFKEIVVGTPQKIVARRLHSAQTSIQEATASKVTVSVGDRSSNLLGECSPAQREAIEALHPESLISCQLQFKQDVFDFPACDVFTVEPGFDAALGQYLCSVTMRRLTDKQLKHLNMKKTSLAVTASIPSSYTSVEKVGAEVPFSPGLYANQAEILLSNHYTSSEVKVFGAVESLENLEVKSGSPAVLAFVKEKSFGLPSFITYTVGVLDPTAGSQGPLSTALTFSSPATNQAITIPVTVAFVLDRRG-------PGPYGASLLSHFLDSYQVMFFTFFALLAGTAVTIIAYHTVCAPRE-------LASPLALTPRASPQHSPHYLASS-PAAFNTLPSGRKASPPSGLWSPAYASH----------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8TEM1-1", "uniprot_id": "PO210_HUMAN", "id": "Q8TEM1-1", "name": "Nuclear pore membrane glycoprotein 210", "aln": "MAARGRGLLLLTLSVLLAAGPSAAAAKLNIPKVLLPFTRATRVNFTLEASEG-CYRWLSTRPEVASIEPLGLDEQQCSQKAVVQARLTQPARLTSIIFAEDITTGQVLRCDAIVDLIHDIQIVSTTRELYLEDSPLELKIQALDSEGNTFSTLAGLVFEWTIVKDSEADRFSDSHNALRILTFLESTY-IPPSYISEMEKAAKQGDTILVSGMKTGSSKLKARIQEAVYKNVRPAEVRLLILENILLNPAYDVYLMVGTSIHYKVQKIRQGKITELSMPSDQYELQLQNSIPGPEGDPARPVAVLAQDTSMVTALQLGQSSLVLGHRSIR-MQGASRLPNSTIYVVEPGYLGFTVHPGDRWVLETGRLYEITIEVFDKFSNKVYVSDNIRIETVLPAEFFEVLSSSQNGSYHRIRALKRGQTAIDAALTSVVDQDGGVHILQVPVWNQQEVEIHIPITLYPSILTFPWQPKTGAYQYT-----IRAHGGSGNFSWSSSSHLVATVTVKGVMTTGSDIGFSVIQAHDVQNPLHFGEMKVYVIEPHSMEFAPCQVEARVGQALELPLRISGLMPGGASEVVTLSDCSHFDLAVEVENQGVFQPLPGRLPPGSEHCSGIRVKAEAQGSTTLLVSYRHGHVHLSAKITIAAYLPLKAVDPSS-VALVTLGSSKEMLFEGGPRPWILEPSKFFQNVTAEDTDSIGLALFAPHSSRNYQQHWILVTCQALGEQVIALSVGNKPSLTNPFPAVEPAVVKFVCAPPSRLTLAPVYTSPQLDMSCPLLQQNKQVVPVSSHRNPRLDLAAYDQEGRRFDNFSSLSIQWESTRPVLASIEPELPMQLVSQDDESGQKKLHG--LQAILVHEASGTTAITATATGYQESHLSSARTKQPHDPLVP------------LSASIELILVEDVRVSPEEVTIYNHPGIQAELRIREGSGYFFLNTSTADVVKVAYQEARGVAMVHPLLPGSSTIMIHDLCLVFPAPAKAVVYVSDIQELYIRVVDKVEIGKTVKAYVRVLDLHKKPFLAKYFPFMDLKLRAASPIITLVALDEALDNYTITFLIRGVAIGQTSLTASVTNKAGQ---RINSAPQQIEVFPPFRLMPRKVTLLIGATMQVTSEGGPQPQSNILFSISNESVALVSAAGLVQGLAIGNGTVSGLVQAVDAETGKVVIISQDLVQVEVLLLRAVRIRAPIMRMRTGTQMPIYVTGITNHQNPFSFGNAVPGLTFHWSVTKRDVLDLRGRHHEASIRLPSQYNFAMNVLGRVKGRTGLRVVVKAVDPTSGQLYGLARELSDEIQVQVFEKLQLLNP-EIEAEQILMSPNSYIKLQTNRDGAASLSYRVLDGPEKVPVVHVDEKGFLASGSMIGTSTIEVIAQEPFGANQTIIVAVKVSPVSYLRVSMSPVLHTQNKEALVAVPLGMTVTFTVHFHDNSGDVFHAHSSVLN-----FATNRDDFVQIGKGPTNNTCVVRTVS--VGLTLLRVWDAEHPGLSDFMPLPVLQAISPELSG-AMVVGDVLCLATVLTSLEGLSGTWSSSANSILHIDPKTGVAVARAV--------GSVTVYYEVAGHLRTYKEVVVSVPQRIMARHLHPIQTSFQEATASKVIVAVGDRSSNLRGECTPTQREVIQALHPETLISCQSQFKPAVFDFPSQDVFTVEPQFDTALGQYFCSITMHRLTDKQRKHLSMKKTALVVSASLSSSHFSTEQVGAEVPFSPGLFADQAEILLSNHYTSSEIRVFGAPEVLENLEVKSGSPAVLAFAKEKSFGWPSFITYTVGVLDPAAGSQGPLSTTLTFSSPVTNQAIAIPVTVAFVVDRRG-------PGPYGASLFQHFLDSYQVMFFTLFALLAGTAVMIIAYHTVCTPRD-------LAVPAALTPRASPGHSPHYFAASSPTSPNALPPARKASPPSGLWSPAYASH----------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F1QC46-1", "uniprot_id": "F1QC46_DANRE", "id": "F1QC46-1", "name": "", "aln": "MEKVG-----LLVLLFILTSSLTNAAKLNIPKVLLPLARSTKINFTLEATEG-CYRWSSNRPEVASIEAVDVDERQCSHRAVLQARSTQPSRLTSIILAEDILTGQVLRCDAIVDVISEIQIESTTRELHLEDSPLELKIHALDSEGNTFSTLASLLFEWTIVKDAEMAGFPDSYNTLRILRFAESAY-TPPGYISEMERVGHQGDIVLVSGIKTGHAKLKAKIQESIYKDVGAAEVRLLILENILLSPAYDVYLLAGTSIKYKVQKIRQGKITELSMPCDQYELQLQNSAVAPNGNLNTPVANLDQSSSTVFALQHGHTNILLDHKSLG-MQGASRLPNSTIYVVEPGYLAFKIHPEDRWVLETGRKYEIFIEVFDKSGHKIYLSDNIRIETTFPAEYFEVLESSVNGSYHHVKAVKQGQTVIDGTLKAVVDQAGSVHALSVPVRNEQDVEIYDPIVLTPAILTFPWQPKEGAYQYI-----IKATGGSGNFSWSSTNSAVATVTVKGMMTTVRDVGVSVIYAHDMRNPLHYGDMKVYVIEPVGMEFSPCAVEARVGLHLDLPLRIFGQLG---DERVTLSDCSHFDMQVDMESTGVFQMLEGRLPPGQSHCSGIRVKALIPGYTTLLVSYTHSNVHLSAKITIAAYPPLKPIDPVS-VAVVTLGSSKDMTFEGGPRPWVLEPSKFFRNLTAEDHSSVSLALFGP-AARTYSTHLVRATCRALGEQVLAVTVGNQPTVTNPFPAVEPAVVKFVCAPPSRLTLTPIYVNPQLDVSCPLLQQNKQVVPVSNYHNPELDVAAFDEQGRKFDNFSSLSMIWESSKVSLASIEPTMPMQLHVHED-NKQKKLHG--HQTVLVHHESGVAGITVTAVGYQTSHLEAAMVLSGFDPLSA------------VSATLDLLLVEDVRVTPDTVTIYNHPDVAAALTLQQGSGYFFVNASVGGVADVTFQESQGIAQVVPLQAGVLQVMVHDLCLTFPSPAKATVHISDILEVYVRVVDKVEIGKSVKAYVRVLDGNKKPFLSKYFSVMNLKLRAASSIISLQTLPDSSEEDTATFLVKGLVIGQTSVSAFIIDKNGR---KITSAPQQIEVFPPFRLLPRKVTVIVGAMMQITSEGGPQPQSNILFSLSHQHIASVNSLGHVQGLAVGNMTVTGVVQAVDTETGKLVVVSKDQVDVEVVQLKAIRIRAPITRMKTGTLMPVYVMGLTSSQTPFAFGNALPGLTFHWSVTKRDILDVHTRHAEASVQLSAEHNFAMSVFGRSKGRTGLRVVMKAIVPLSGHLEDDALELHDEIQIQVYEKLQLLNP-ELEAEQILMSPNSLLKLQTNRDGVGSLLYRVLDCPDRAALVQVDDKGHLTSGSMTGTASLQISAQETFGVNQTVIIAVKVVPVSYLRLSTSPVIYTSNRETVSAIPLGAILTFTVHFHDSTGETLHSHNSMLS-----FSTNRDDLVQVSKGLSNGTLTMRTVN--VGLTLLGVWDSEQAGLADFLALPVQHAIHPAQAQ-RLVVGDVVCFSAQFINQDGALGVWSSSSSALLEVEPRTGAAVARDK--------GTVTVYYEIAGLLRTYREVLIEG-----ASRTSSMTPSVKKERDLKVLMSTREAGNNLIGSCSSSQLDSIALLHPESSISCQLQFTSSAVDFSAHDVYHTHTAFDASTGYYSCALSFKPMSEQQVKVLSMSMTEVEVTAAVQGAHFIGEQISARLPVNPGIYADQTDIILSNQHTSADLTIYGSTAALQQLEVKSSSPVIAIEEKEVSLSFPSYARYTVRVVNP----QGALTASVSVSSSSSDQVLLIPVSVMHLTASSTSVQAHMVEGADGPNIFQQFIDSYQVMFFTLFALLAATAVVIIVCHALFSPRD-------PVNHPAFIQKTPPPAGVAKLTES--PFSNSVSSDLKGSPRLRLYSPDYSSR----------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A1Z6H7-1", "uniprot_id": "PO210_DROME", "id": "A1Z6H7-1", "name": "Nuclear pore membrane glycoprotein 210", "aln": "-----MDSILCMILLILVRNHASEAARLNHPRVLLPIFEDKAINFTLEVDEPNCYKWSSSRQDLISVMPIYKGFSECAYQAVVTVRTHDRRRNTAIVFAEEVQTGETLRSDVIVDVIASLNVRTATRQLYLEEAPAMFELHAFDEQGNEFFTLEGIEFDWEILEPG-----SKRPTAMRYLTFTDSPYHTVPPTIEKFEADGKKGHMILLEGINTGTAKVTIAMPQAEYKHVRPVEVYISVLANIIIEPS-EVTIMAGDSVSFRILQLKMDRLHVIDN--NQYYLEVEDSS----------IAYLRGNS--ATGAALGRTQVFLRDRNMADSDEVQKGPSALLTVAYPNRLSISLLPHLNWVTVQGEHHAIALDLFAADGQKITMGTKYSINSEVDESFFAIVDRTRNGSRLFGQAKKEGITQVYGSYKDLSVQAELQIFEELQLAPTKVVLPYDPNSLKPLKLQFHASGGDNNYAWFSGNPQVIQIDTQGQATTEIRDVKSAYVNQEVLKDGGKLTAHTTVKVALSKNQKISRVAHIYFLPPERLQITRSNFETALKDFVHVHVGVYARIN---NSEVPYTSCDNLHFQLDFSQPILQLEGNEGAEAAHEACHVLRLRATAVGTTSLRVSYMYMDKVLYDIIDLYVFEPLVVLNPIENEVVLPVGSSRNIIYANGPQRSFTVAAEIIQSTAFDEK---ILKVSKLEFDTQNLITAFTVLCRELGETQFTYRVHNSLPTSSFALYQSEVTTKVHCVRPR---FLKLYARHNLRDSCPLEKRTSLLFLKDPENKIEIEIEVHDSNNRRLMNISSLGLDWEFSAGEERYQKNIIPHRQISELEFNHGVTLPSRDLLVLTLSEVATNFRIKGTVSQYNDKLLAQHGIHAERPPFGIKNPQTGLIYTPLIENEIRLHAVNSTLLPKDYMSIFLASGYSERIPIAQGSGYLQLELSEAGIVQVEYNENTRILVLTPLRLGHVRLELTDRCLMN-EPSHLSISVVGIGAIEVVSMDRLERTTRIEAIVRLFDTNDNLLLVDQSKLSAYDLSEVVADQSILSVRLGEQENVGPGEIRYTITGNQVGETKILFQSGKGIYKVASDPLNIQVFAPIRLFPRDSTLVVGSSIQVYFHGGPHPNTNMIISVEKEQVATISS-TVVTAHKLGTTKIVGKCLLKNPVTGKDEVVSQDSVEVHVVALKGVQIRTPLVRIHSGAVMPATLWGLS-DLSPMILG-TLQNTKISWKVSQPQVVEIFNVFTTAGIEYQSGDLISVRVRALNPG--------KATITASVTLADGTILPPATVDLQVFKTLELVTPNAIKMDSILAAPRSILQLKSN---MDNVVYKLDDRSN--GIVSVTPDGLVHTKDSLGRDLIIATTAD-----QSLPIGIEVKNVQYILVTLMPILKLR--ELEHKIPRGMNFVFKVSLHDNLGNELSHNIEDFNGLRYELGNKDDVDVQIDNNLTFALNLMRETNNVIGISLKDSTGVKHS--MDFIKLSVVESDNLFPTKTIFSVGDIICFDSPLT----LSSTWRSSNEQIVYINKHTGIAQVLSHRLKPGEKIEITNGDETKRGGFLKYDLEVRESDTILFVKSVDTFSGPEYRGQLVIRNHLQSEKYSNLIAQNVSKCARELGSVPVN-FFTCRLAAKDALGRN-LLKMYKVDALFEPSIGQYSCRLQLLTGFIELLSIVKTHDVYLELEAVVAKG----VSDKMSLKLVPGIKVFPESVRVTDLKP-HEIHISGLDKALLKVQVKPSDSKYFAVDFIEHG--HGLSKYRLELFDDLPLDENFY---ILVVSPDTKQSIEVPIIGNTMLAPKCT------DRRYGGPLVYRILENLGFVLTTTVIVIISIWVYMSCFQTQGVTQVNFEAFKKGKSRTELMQQSGRSSQDDTFGDS--FNVRNFSPDRRRPPSNALSESYIYGHPRLNSSNRSENSTSFS", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ::: : **:** *:****: . . :*****. * **:* *.* :: *: .: . :*: :**: .* : * *:*::**:: **:.**.*.***:* ::: ::**:*:**::* ::::*:*.:** * ** .: *:* *:: .. .::* * * :*.* * *.::* .::*. :*:.*::** :*:. : :: **.* ..** : :* **::.*: :* ::.* *: ::: ::: .:: :. :** *::::* :* * .: . . *::.:.* .:.: : ..: *.: : *. .. *.:.: * .** *. : : :::* .:*: . : *:: . .:* ::. : *** :* : * * : .: . : * .: : : * : * * * * * . . * : : . .*: : . . * *. : : . :.: . :* ::*.: * :::: . .*: : :.: : : . : .. *. :.*.::.: ::... : .. . * ::::* * *:* *** : . * * : .: ** ::* . .::.:***::: : .**: . .:::::. : :: * : . *: *** :: * * . :. . ...* *. * : :*. :* **** ::.. :. . .: ::: ..*.:.*:: *:***.: ** : * : . : . .* . .: : . : *. *. *: . * *: :. : * *:.. :. : ::*: .. : : :****: :: * .: .* ::: : : ** * : : * ** *:: : : .* : : :*::* . ::* **::* .: :* . . .* . :: :: . :: . . :: *: : : : *: :: * . :*:**.*:**:**. *:::*: :*: .***:*::*:::*:.:: :* :.: * . :*. .: * :. *** ::*:* *:*.*: *:.::**:*: *:::*: ** : *:: .*: :* :: . .: *.*:: ::::: . ..:. . ::: * . * ** . : * . :::**::.*.*:.* :: :.** :*.* ::*::* : *:: * .: :* .* : : . * : : : *:: :.::* :.*: :: *:: * :* * ..* * :**. *: : : . :. :..: * **:.:. : :* .. :*::* . :: **: *.* .: : . ***::*: : : ..* ** :: :: :** * . .. * : .: : . . . . : .** .. . : : : ::*: . .:: ... *:.: * * * : : : . :. . : : * : . . : . **: . .: ::: . :: : * * :::*:.... . * : :.: :. : . *. :.* : :*: : * :. ::::. .:: * . :: . * : :: .: : :: : * . ... : .* * .. .: ", "identical_positions": 319, "similar_positions": 679, "identity": "16.28%" }, { "cls_id": "homologset.agr.MGI:1859559", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q91WU2-1", "uniprot_id": "S22A7_MOUSE", "id": "Q91WU2-1", "name": "Solute carrier family 22 member 7", "aln": "------MGFEELLHKVGGFGPFQLRNLVLLALPRFLLPMHFLLPIFMAAVPAHHCALPDAPAN----LSHQDLWLKTHLPRETDGSFSSCLRFAYPQALPNVTLGTEVYNSGEPEGEPLTVPCSQGWEYDRSEFSSTIATE-------------WDLVCEQRGLNKVTSTCFFIGVLLGAVVYGYLSDRFGRRRLLLVAYVSTLALGLMSAASVNYIMFVTTRMLTGSALAGFTIIVLPLELEWLDVEHRTVAG-VISTTFWTGGVLLLTLVGYLIRSWRWLLLAATLPCVPGIISIWWVPESARWLLTQG----RVEEAKKYLSICAKLNGRPISED--SLSQEALNKVITMERVSQRPSYLDLFRTS---QLRHVSLCCMMMWFGVNFSYYGLTLDASGLGLTVYQT----------------QLLFGAVEVPSKITVFFLVRLVGRR-LTEAGMLLATALTFGIS--------LLVSSDTKSWITALVVIGKAFSEAAFTTAYLFTSELYPTVLRQTGMGFTALIGRLGASLAPLVV------------LLDGVWLLLPKLAYGGISFLAACTVLLLPETKKAQLPETIQDVE------RKGR----KIDRSGTELA-----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q5RLM2-1", "uniprot_id": "S22A7_RAT", "id": "Q5RLM2-1", "name": "Solute carrier family 22 member 7", "aln": "------MGFEDLLDKVGGFGPFQLRNLVLMALPRMLLPMHFLLPVFMAAVPAHHCALPGAPAN----LSHQDLWLEAHLPRETDGSFSSCLRFAYPQTVPNVTLGTEVSNSGEPEGEPLTVPCSQGWEYDRSEFSSTIATE-------------WDLVCQQRGLNKITSTCFFIGVLVGAVVYGYLSDRFGRRRLLLVAYVSSLVLGLMSAASINYIMFVVTRTLTGSALAGFTIIVLPLELEWLDVEHRTVAG-VISTVFWSGGVLLLALVGYLIRSWRWLLLAATLPCVPGIISIWWVPESARWLLTQG----RVEEAKKYLLSCAKLNGRPVGEG--SLSQEALNNVVTMERALQRPSYLDLFRTS---QLRHISLCCMMVWFGVNFSYYGLTLDVSGLGLNVYQT----------------QLLFGAVELPSKIMVYFLVRRLGRR-LTEAGMLLGAALTFGTS--------LLVSLETKSWITALVVVGKAFSEAAFTTAYLFTSELYPTVLRQTGLGLTALMGRLGASLAPLAA------------LLDGVWLLLPKVAYGGIALVAACTALLLPETKKAQLPETIQDVE------RKST----QEEDV----------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9Y694-1", "uniprot_id": "S22A7_HUMAN", "id": "Q9Y694-1", "name": "Solute carrier family 22 member 7", "aln": "------MGFEELLEQVGGFGPFQLRNVALLALPRVLLPLHFLLPIFLAAVPAHRCALPGAPAN----FSHQDVWLEAHLPREPDGTLSSCLRFAYPQALPNTTLGEERQSRGELEDEPATVPCSQGWEYDHSEFSSTIATES-----------QWDLVCEQKGLNRAASTFFFAGVLVGAVAFGYLSDRFGRRRLLLVAYVSTLVLGLASAASVSYVMFAITRTLTGSALAGFTIIVMPLELEWLDVEHRTVAG-VLSSTFWTGGVMLLALVGYLIRDWRWLLLAVTLPCAPGILSLWWVPESARWLLTQG----HVKEAHRYLLHCARLNGRPVCED--SFSQEAVSKVAAGERVVRRPSYLDLFRTP---RLRHISLCCVVVWFGVNFSYYGLSLDVSGLGLNVYQT----------------QLLFGAVELPSKLLVYLSVRYAGRR-LTQAGTLLGTALAFGTR--------LLVSSDMKSWSTVLAVMGKAFSEAAFTTAYLFTSELYPTVLRQTGMGLTALVGRLGGSLAPLAA------------LLDGVWLSLPKLTYGGIALLAAGTALLLPETRQAQLPETIQDVE------RKSAPTSLQEEEMPMKQVQN---", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0ACD6B6B5-1", "uniprot_id": "A0ACD6B6B5_DANRE", "id": "A0ACD6B6B5-1", "name": "Solute carrier family 22 member 6", "aln": "------MKFEDLITEINGFGRFQKMILCISFVGRFIIPCHFLLSNFIAAIPSHHCDISFLDADGLFGNLTEEERLIVSVPTQEDGSPVSCHMFSHPQFQLLINSSSS--------SDLPVVECQNGWHFDNSTFISTLATQ-------------WDLVCDNRGLNKAVATIFFVGVMFGAAFFGGMSDRFGRKPMLLVSYISGMAFALASVFSTSFTMFAVLRFFSGFTITGIVIVSSVLNLEWVDIEHRRLVS-IIDSMAWAVGSTSLALIAYFIRDWRWLTVAVTSPLVLCTILWWWVPESARWLIANG----DVEKAHYYLHKCAVMNRKAEVTS--RIKPEALAISVS-DQGKKKYTYLDLVRTP---KMRKLAMLTGTVWFCVATMTYGISLNITSFGLNMYLT----------------QFVYGAIEVPSKLIVYYLLEKIGRR-KTEAGAQLFAGISLMIN--------IFIPKDQWIGRTVVAVLGKGFAVAAFCTIVLYSSELYPTVLRQNGMGYNSFLARLGVSVAPLVL------------LLDTFWGQFSQTILCSVALIASVVAWNLPETRDRCLPETIEDVEGTGKTPNKDQEKQENEEKIAMNEPQ----", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VRQ8-1", "uniprot_id": "Q9VRQ8_DROME", "id": "Q9VRQ8-1", "name": "Major facilitator superfamily (MFS) profile domain-containing protein", "aln": "MPPRDCEKYENFLLFIGDFGPFQKRLLFWMMPAAFLFAFTYFGQIFMILLPKNHWCRVRELEG-----LPESEQKNRGIPKKQDGSFENCFMYNVPYDSNATN---------DANQTRSPIPCNNGWIYDRKEVPYESIAT------------EYNWVCDKRDFGTYSVVVYFVGCIVGCLCFGFITDHSGRLPALFLANSCSMIGGCVSVVCKDFPCFAASRFVAGLSMNYCFVPIYILTLENVGIKYRTLVGNLALTFFFTLGACLLPWLAYVISNWRHYAMVVALPIVFMILTSLLAPESPSWLMSVG----KVDRCIEVMKEAAKANGKIISEEVWSEMRECYELKFANEQLGKQYTSLDLFKTF---PRLVVLTILIVTWMTVALAYDAHVRVVEILDTDIFIT----------------FSLSSLVEIPAGIVPMLLLDRIGRKPMMSAVMLLCAASSLFVG--------ILKG---HWNASTAAIAARFFATMAYNVGQQWASEILPTVLRGQGLAIINIMGQMGALLSPLVL------------STHRYYRPLPMFIITLVSVIGALIILFLPETKGATMPQTLDEAE-------KRWTLRCRDRKINEDL------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VDS0-1", "uniprot_id": "Q9VDS0_DROME", "id": "Q9VDS0-1", "name": "Solute carrier family 22 member 13", "aln": "--------------MVNPSPARGGESTAPHILPNEMENDVDKRIATPPPAPAGSDVIADVVGDFG--IWQLRTILIIFLCKIPAAWFMACIIFTGPELYPGSEFTCDTSYLTSSSNSSFSISDNQCYVLDESTGTSSECEQFNYVSSFDSLIMQFNLVCLRDIFVAWTQYWHLFGVLVGGVMGTKMMLGISPRSTYCVGAVAQILCGVVTGYARDFSLHCAFRCLSAVCCAIMFTAGQAIFADITAGMHR-IGAIILYDTFWSIGVILLPGLSSFFNSWSLIYVGITFPTIMLILLLYWTPDSPRWLLRHAADRFSIDNVEQILREGAAINDRSFKIPP-DFRQQLEQLSERLKAQPPPAPWTELWKGK---RAKTHMVAAHLALAFFVINFMGMLLNIRSFGRDYLVPN---------------TIAMGFSEIIGCFLALHFTLKHNKWKWQCAGVFNILAGILGCMGWIFTNADSMDADLKVSLWMIIATIPKAAVSCAQSMILACMNELMPANKKQLFVFSVVTWARVWLLSAPFFN------------VLRKIDTAMSLTSYCVFSILGGICTSLLLTPRLSVSPVVPHLEQ---RNTKEQSPLNAPVWTVESDVNNTRL-", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P25297-1", "uniprot_id": "PHO84_YEAST", "id": "P25297-1", "name": "Inorganic phosphate transporter PHO84", "aln": "--------MSSVNKDTIHVAERSLHKEHLTEGGNMAFHNHLNDFAHIEDPLERRRLALESIDDEGFGWQQVKTISIAGVGFLTDSYDIFAINLGITMMSYVYWHGSMP----GPSQTLLKVSTSVGTVIGQFGFGTLADIVG------------------RKRIYGMELIIMIVCTILQTTVAHSPAINFVAVLTFYRIVMGIGIGGDYPLSSIITSEFATTKWRGAIMGAVFANQAWGQISGGIIALILVAAYKGELEYANSGAECDARCQKACDQMWRILIGLGTVLGLACLYFRLTIPESPRYQLDVN-AKLELAAAAQEQDGEKKIHDTSDEDMAINGLERASTAVESLDNHPPKASFKDFCRHFGQWKYGKILLGTAGSWFTLDVAFYGLSLNSAVILQTIGYAGSKNVYKKLYDTAVGNLILICAGSLPGYWVSVFTVDIIGRKPIQLAGFIILTALFCVIG-------FAYHKLGDHGLLALYVICQFFQNFGPNTTTFIVPGECFPTRYRSTAHGISAASGKVGAIIAQTALGTLIDHNCARDGKPTNCWLPHVMEIFALFMLLGIFTTLLIPETKRKTLEEINELYHDEIDPATLNFRNKNNDIESSSPSQLQHEA", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . : . . . : . .. . : : :. . . . . : . : . * : *:*. : : : : . . . :: : . . : . .: . .: * . . . .* *: : .:: : . .:. : .: . . ", "identical_positions": 6, "similar_positions": 63, "identity": "0.96%" }, { "cls_id": "homologset.agr.MGI:1859565", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q794H2-1", "uniprot_id": "NP1L3_MOUSE", "id": "Q794H2-1", "name": "Nucleosome assembly protein 1-like 3", "aln": "MAEADPKMVTEPGAHGVAEEAMASTACDSGDESDSNSSSSTNSCSSSGSSSSGSSSSSSSSSSSSSSSSSSSSGSSGSSSNGSHLNRKKRVPEPSRRAQRRPSGK--LFLDKLPQAVRNRVQALRNIQNECDKVDTLFLRAIHDLERKYAELNKPLYDKRFQIINAEYEPTEEECEWNSE-EEFSGDEEMQDDTPNEMPPLEGEEEEESCNEKAEVKEEGTHVPEEVPEAKVEEEEAPKETPEVKTEEKDIPKEGAEEKAEEQESSKEIPEVKGEEKADSTDCIDIAPEEKEDVKEVTQANTENKDQP-TEEFTPRAPAREAQKRVPETRPEEGVNIKRARKGKPKKEDP-KGIPDYWLTVLKNVDKLGPMIQKCDEPILKFLSDVSLKFSNP-GQPIGYTFEFHFLPNPYFRNELLMKTYIIRSKPDHYDPFFAWGWEIEECKGCKIDWRR-GKDVTVTTTRSRPGIT--GEIEVQPRVVPNASFFNFFSPPEIPLIGKLEP---REDAILDEDFEIGQILHDNVILKSIYYFTGEINDPYYHDFRDYGNRKYYK-----------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q924R9-1", "uniprot_id": "NP1L3_RAT", "id": "Q924R9-1", "name": "Nucleosome assembly protein 1-like 3", "aln": "MAEADPKMVTEPAAQGVAEEAMASSACDSGDESDSNSSSSTTSCGSTGSSS--------SSSSSSSSSSSSSSGSSGSSSNGSHLHQKKRVPGPSRRAQRRPSGK--LFMDKLPQAVRNRVQALRNIQNECDKVDTLFLRAIHDLERKYAELNKPLYDKRFQIINAEYEPTEEECEWNSE-EEFSGDEEMQDDTPNEMPPLEGEEEEEIGKENTEVKEEVKDVPEEVPEAKVEEEEAPKETSEVKTEEKEIPKEGPEEKAEEQESSKEFPEVKVEEKTDSTDCIDIAPEEKEDLKDVTQANAEYTDQP-TEDSTPRAPVREAQKRVPETRPEERVNIKRARKGKPKKEDPPRGIPDYWLTVLKNVDKLGPMIQKCDEPILKFLSDVSLKFSNP-GQPISYTFEFHFLPNPYFRNELLMKTYIIRSKPDHYDPFFAWGWEIEECKGCKIDWRR-GKDVTVTT-RSRPAIT--GEIEVQPRVVPNASFFNFFSPPEIPLIGKLEP---KEDAILDEDFEIGQILHDNVILKSIYYFTGEINDPYYHDFRDYGNRKYYK-----------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q99457-1", "uniprot_id": "NP1L3_HUMAN", "id": "Q99457-1", "name": "Nucleosome assembly protein 1-like 3", "aln": "MAEADFKMVSEPVAHGVAEEEMASSTSDSGEESDSSSSSSSTSDSSSSSST-----------SGSSSGSGSSSSSSGSTSSRSRLYRKKRVPEPSRRARRAPLGT--NFVDRLPQAVRNRVQALRNIQDECDKVDTLFLKAIHDLERKYAELNKPLYDRRFQIINAEYEPTEEECEWNSEDEEFSSDEEVQDNTPSEMPPLEGEEEEN---------------PKENPEVKAEEKEVPKEIPEVKDEEKEVP--------------KEIPEVKAEEKADSKDCMEATPEVKEDPKEVPQVKADDKEQPKATEAKARAAVRETHKRVPEERLQDSVDLKRARKGKPKREDP-KGIPDYWLIVLKNVDKLGPMIQKYDEPILKFLSDVSLKFSKP-GQPVSYTFEFHFLPNPYFRNEVLVKTYIIKAKPDHNDPFFSWGWEIEDCKGCKIDWRR-GKDVTVTTTQSRTTAT--GEIEIQPRVVPNASFFNFFSPPEIPMIGKLEP---REDAILDEDFEIGQILHDNVILKSIYYYTGEVNGTYYQFGKHYGNKKYRK-----------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VAZ1-1", "uniprot_id": "Q9VAZ1_DROME", "id": "Q9VAZ1-1", "name": "", "aln": "-------------------------------------------------------------------------------------METVRNRNPPRMKYTAPPKM--ESDLNFTEKEKKTLTELKQLYLETINLDVALQRDIYNIEKKYEDKHNIIFDKRKKILDEFRKQNHGDVETNQS-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------VPNFWLRVLK--ASYTEFISKRDEKILECLSDIRSRLYN--EPVVKFDIEFHFDPNDYFTNTVLTKTYFLNCLPDPDDPLAYDGAEIYKCEGCVIDWKQ-TKDQTKTENQEPS-------------------FFEFFSPPLLPED-TLDPNYCDVNAMLQNDFEVGFYLKERVIPKAVIFFTGEIADCQSSSGSETESEDTEDESDAEEEDGVDK-----------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9W1G7-1", "uniprot_id": "Q9W1G7_DROME", "id": "Q9W1G7-1", "name": "", "aln": "--------------------------------------------------------------MDAPAEGHVDPESCNEIEDEKSGSDCQSMPAYMNSVMRRQYLQ--QMVKMLPAPVQNRIVFLKNLQLQHLNIEAQFFEDVYKLEQKYQVQYQPLFDKRREIIEGKVDPAEEKPQWKEP------------------------------------------------------------------------------------------------------------------------------------------------ESSTDNEADAEHFREALSSLKSIPKDAKGIPGFWLTVFRNTAIMSEMVQPHDEPAIRKLIDISIKYDN----GHSYTLEFHFDKNEYFSNSVLTKQYVLKSTVDPNDPFAFEGPEIYKCTGCTINWEK-KMNLTVKTIRKKQKHKERGAVRTIVKQVPTDSFFNFFSPPEVPSDQEEVDD--DSQQILATDFEIGHFLRARIIPKAVLYYTGDIVDDEDDEDEEEYDENEEDEYDDDDAPPPKGPKSAGIKKQSPNDCPNQ------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P25293-1", "uniprot_id": "NAP1_YEAST", "id": "P25293-1", "name": "Nucleosome assembly protein", "aln": "--------MSDPIRTKPKSSMQIDNAPTPHNTPASVLNPSYLKNG-----------------NPVRAQAQEQDDKIGTINEEDILANQPLLLQSIQDRLGSLVGQDSGYVGGLPKNVKEKLLSLKTLQSELFEVEKEFQVEMFELENKFLQKYKPIWEQRSRIISGQEQPKPEQIAKGQE------------------------------------------------------------------------------------------------------------------------------------------------IVESLNETELLVDEEEKAQNDSEEEQVKGIPSFWLTALENLPIVCDTITDRDAEVLEYLQDIGLEYLTDGRPGFKLLFRFDSSANPFFTNDILCKTYFYQKELGYSGDFIYD-----HAEGCEISWKDNAHNVTVDLEMRKQRNKTTKQVRTIEKITPIESFFNFFDPPKIQNEDQDEELEEDLEERLALDYSIGEQLKDKLIPRAVDWFTGAALEFEFEEDEEEADEDEDEEEDDDHGLEDDDGESAEEQDDFAGRPEQAPECKQS", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . :. :: : *: : : ::: : :..:*.*: : ::::* .*:. . . . :*.:** .:. : * :. * *: . . :.*. * :* * :* * *. . . . : .. ** *.*. : * **:**.** : : * *:.:* *: .:* ::: ::** . ... . ", "identical_positions": 36, "similar_positions": 77, "identity": "6.09%" }, { "cls_id": "homologset.agr.MGI:1859568", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9QX82-1", "uniprot_id": "MUC24_RAT", "id": "Q9QX82-1", "name": "Sialomucin core protein 24", "aln": "MSGASRGLFWAATCLAALCLSAAQSN-SSASPNVTDPP----TTTSKVVPTTLTTTKPPETCESFNSCVSCVNATLTNNITCVWLDCHEANKTYCSS-ELVSNCTQKTSTDSCSVIP-TTPVPT-NSTAKPTTRPSSPTPTPSVVTSAGATNTTVTPTSQPERKSTFDAASFIGGIVLVLGVQAVIFFLYKFCKSK-ERNYHTL--------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9R0L9-1", "uniprot_id": "MUC24_MOUSE", "id": "Q9R0L9-1", "name": "Sialomucin core protein 24", "aln": "MSGSSRRLLWAATCLAVLCVSAAQPNITTLAPNVTEVP----TTTTKVVPTTQMPTVLPETCASFNSCVSCVNATFTNNITCFWLHCQEANKTYCAN-EPLSNCSQVNRTDLCSVIPPTTPVPT-NSTAKPTTRPSSPTPTPSVVTSAGTTNTTLTPTSQPERKSTFDAASFIGGIVLVLGVQAVIFFLYKFCKSK-ERNYHTL--------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q04900-1", "uniprot_id": "MUC24_HUMAN", "id": "Q04900-1", "name": "Sialomucin core protein 24", "aln": "MSRLSRSLLWAATCLGVLCVLSADKN-TTQHPNVTTLAPISNVTSAPVTSLPLVTTPAPETCEGRNSCVSCFNVSVVN-TTCFWIECKDE--SYCSHNSTVSDCQVGNTTDFCSVST-ATPVPTANSTAKPTVQPS-PSTTSKTVTTSGTTNNTVTPTSQPVRKSTFDAASFIGGIVLVLGVQAVIFFLYKFCKSK-ERNYHTL--------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "M9PHX2-1", "uniprot_id": "M9PHX2_DROME", "id": "M9PHX2-1", "name": "", "aln": "-MNRQAKFLILCLFVGLFSANLCEEVTTPAPADTTTQE----SKNTTTPPDTTTTVTPPSTSTTSTTTEKTTTTPPIT-----------------TSTEKTTTSTTPASTTSSTTPASTTSSTTPATTTTTPGTTSTTTPSPNSTTTTPPPHTSTTPAPKPVPCGHFDGSSFIGGIVLTLGLLAIGLVAYKFYKARNERNYHTLXAATAFTSAFNAAAGAAAASSSAASTDAERVRFVQPSIPLRSPPTQPPPPPPTHMGGSGGGAAAAPQNCSPSARDRLLHT", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . :: . :. :. .: :. .:.* ..: . . . .. *.*. .: . ... . : . : . * .:. . :*. .* :*:... .* .:.:.. .*:: ..:.: **:.:* . **.:********.**: *: :. *** *:: ******* ", "identical_positions": 36, "similar_positions": 76, "identity": "12.68%" }, { "cls_id": "homologset.agr.MGI:1859606", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q5U2Y0-1", "uniprot_id": "WIPI4_RAT", "id": "Q5U2Y0-1", "name": "WD repeat domain phosphoinositide-interacting protein 4", "aln": "----------MTQQPLRGVTSLHFNQDQSCFCCAMETGVRIYNVEPLMEKGHLDHEQVGS-------VGLVEMLHRSNLLALVGGGSSPKFSEISVLIWDDAREGKDSKDKLVLEFTFTKPVLAVRMRHDKIVIVLRNRIYVYSFPDNPRKLFEFDTR-------------DNPKGLCDLCPSLEKQLLVFPGHKCG-SLQLV----------------------------------------------------------SKEKLVELRRGTDPATLYCINFSHDSSFLCASSDKGTVHIFALKDTRLNRRSALARVGKVGP------------MIGQYVDSQWSLASFTVP------------------------AESACICAFGRNTSKNVNSVIAICVDGTFHKYVFTP--DGNCNREAFDVYLDICDDDDF------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q91VM3-1", "uniprot_id": "WIPI4_MOUSE", "id": "Q91VM3-1", "name": "WD repeat domain phosphoinositide-interacting protein 4", "aln": "----------MTQQPLRGVTSLHFNQDQSCFCCAMETGVRIYNVEPLMEKGHLDHEQVGS-------VGLVEMLHRSNLLALVGGGSSPKFSEISVLIWDDAREGKDSKDKLVLEFTFTKPVLAVRMRHDKIVIVLRNRIYVYSFPDSPRKLFEFDTR-------------DNPKGLCDLCPSLEKQLLVFPGHKCG-SLQLVDLASTKPGTSSA-------PFTINAHQSDVACVSLNQPGTVVASASQKGTLIRLFDTQSKEKLVELRRGTDPATLYCINFSHDSSFLCASSDKGTVHIFALKDTRLNRRSALARVGKVGP------------MIGQYVDSQWSLASFTVP------------------------AESACICAFGRNTSKNVNSVIAICVDGTFHKYVFTP--DGNCNREAFDVYLDICDDEDF------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9Y484-1", "uniprot_id": "WIPI4_HUMAN", "id": "Q9Y484-1", "name": "WD repeat domain phosphoinositide-interacting protein 4", "aln": "----------MTQQPLRGVTSLRFNQDQSCFCCAMETGVRIYNVEPLMEKGHLDHEQVGS-------MGLVEMLHRSNLLALVGGGSSPKFSEISVLIWDDAREGKDSKEKLVLEFTFTKPVLSVRMRHDKIVIVLKNRIYVYSFPDNPRKLFEFDTR-------------DNPKGLCDLCPSLEKQLLVFPGHKCG-SLQLVDLASTKPGTSSA-------PFTINAHQSDIACVSLNQPGTVVASASQKGTLIRLFDTQSKEKLVELRRGTDPATLYCINFSHDSSFLCASSDKGTVHIFALKDTRLNRRSALARVGKVGP------------MIGQYVDSQWSLASFTVP------------------------AESACICAFGRNTSKNVNSVIAICVDGTFHKYVFTP--DGNCNREAFDVYLDICDDDDF------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q7ZUX3-1", "uniprot_id": "WIPI4_DANRE", "id": "Q7ZUX3-1", "name": "WD repeat domain phosphoinositide-interacting protein 4", "aln": "----------MAQQ--RGVNSLQFNQDQSCFCCAMETGVRIYNVEPLMEKGHLDHEQVGS-------IALCSMLHRSNLLAVVGGGVNPKFSEISVLIWDDAREVRDPKDKLVLEFTFTKPVLAVRMRHDKIIIILKNRIYVYSFPDNPVKLFEFDTR-------------DNPKGLCDLCPSLEKQLLVFPGHKCG-SLQLVDLSNTKPGTSSA-------PFTINAHQSEIACLALNQPGSVVASASRKGTLIRLFDTTTRDKLVELRRGTDPATLYCINFSHDSSFLCASSDKGTVHIFALKDTKLNRRSALARVGKVGP------------VIGQYVDSQWSLANFTVP------------------------AECACICAFGKNTSKNVNSVIAICVDGTFHKYVFTP--DGNCNREAFDVYLDICDDDDF------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P50079-1", "uniprot_id": "HSV2_YEAST", "id": "P50079-1", "name": "SVP1-like protein 2", "aln": "MDVRRPIREAVNNRRKPKFLSVSFNQDDSCFSVALENGFRIFNTDPLTSKLSKTFKESATNQSRGTGIGYTRMLYRTNYIALVGGGKRPRHALNKLIIWDDLLQ------KETITLKFMSSIKDVFLSRIHIVVVLENTIEIFQFQTNPQRICPILDIPPNGSVDYVVCSSKHLQSQASQSQSKILEIIAFPSNKCVGQIQVADLSQIKYNSQNPKESALLPTSIIKAHKNPIKLVRLNRQGTMVATCSVQGTLIRIFSTHNGTLIKEFRRGVDKADIYEMSFSPNGSKLAVLSNKQTLHIFQIFETTNTETNTPDHSRANGSSHPLKNYIPKGLWRPKYLDSVWSICNAHLKNPIFDAHRNDNSGDVTHDNEFYKDRCRIGWCQDSNNREQDDSLVLVWQNSGIWEKFVILEKEQQDSSKTHYSLNESLRNEDTKSAGEPTRWELVRESWREL", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : :: . *: ****:***. *:*.*.**:*.:** .* .:: .: :. **:*:* :*:**** *:.: .::**** : * .: :.* ..: * : : :*:::*.* * ::.* .* :: : .: :. .. . * :::.**.:** .:*:. . : *:***.* * :* :.** :.* *.. *:* *:*** : :* .. .: : *. :*:** **:.. : * ..* .:: . *:. .* :.*:*: : :..: :.: .: ::: ", "identical_positions": 76, "similar_positions": 123, "identity": "16.74%" }, { "cls_id": "homologset.agr.MGI:1859607", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A0G2JTX2-1", "uniprot_id": "A0A0G2JTX2_RAT", "id": "A0A0G2JTX2-1", "name": "PRA1 family protein", "aln": "--------------MS-EVRLPPLRALDDFVLGSARLAAPDLGDPQRWCHRVINNLLYYQTNYLLCFGISLALAGYIRPLHTLLSALVVAVALGVL--VWAAETRAAVRRCRRSHPAA------------CLAAVLAVSLFILWAVGGAFTFLLCITAPVLLILLHASLRLRNLKNKIENKIESIGLKRTPMGLLLEALGQEQEAGS-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9JIG8-1", "uniprot_id": "PRAF2_MOUSE", "id": "Q9JIG8-1", "name": "PRA1 family protein 2", "aln": "--------------MS-EVRLPPLRALDDFVLGSARLAAPDPGDPQRWCHRVINNLLYYQTNYLLCFGISLALAGYIRPLHTLLSALVVVVALGVL--VWAAETRAAVRRCRRSHPAA------------CLAAVLAISLFILWAVGGAFTFLLSITAPVFLILLHASLRLRNLKNKIENKIESIGLKRTPMGLLLEALGQEQEAGS-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O60831-1", "uniprot_id": "PRAF2_HUMAN", "id": "O60831-1", "name": "PRA1 family protein 2", "aln": "--------------MS-EVRLPPLRALDDFVLGSARLAAPDPCDPQRWCHRVINNLLYYQTNYLLCFGIGLALAGYVRPLHTLLSALVVAVALGVL--VWAAETRAAVRRCRRSHPAA------------CLAAVLAVGLLVLWVAGGACTFLFSIAGPVLLILVHASLRLRNLKNKIENKIESIGLKRTPMGLLLEALGQEQEAGS-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VJ59-1", "uniprot_id": "Q9VJ59_DROME", "id": "Q9VJ59-1", "name": "PRA1 family protein", "aln": "MTTPSTSVGDAAAALSGNLQLPPLRTLDDFILGSARFQLPNLKDFEKWGNRVVKNLLYYQTNYFLLFITIYVLMIFFNPSKIITGLLVQALIIGVIWQFFSGKSKKNFIASRLTGGNANAAEQNAQQKWYILAGALLGGYLLLHLLSAVLLTIFTVLLPISLTFIHASLRLRNIKNKLTNSIESFAPS-TPMGSLLDALNVRAEGVFN", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :* :::*****:****:*****: *: * ::* :**::*********:* * .* :..* : : . ** .: :**: .::.::: . .* : * **..* . ::* ... :: : *: * ::********:***: *.***:. . **** **:**. . *. ", "identical_positions": 69, "similar_positions": 59, "identity": "33.17%" }, { "cls_id": "homologset.agr.MGI:1859608", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P86182-1", "uniprot_id": "CCD22_RAT", "id": "P86182-1", "name": "Coiled-coil domain-containing protein 22", "aln": "MEEADRILIHSLRQAGTAVPPEVQTLRAFTTELVVEAVVRCLRVINPDVGSGLSHLLP-PAMSARFRLAMSLAQACMDLGYPLELGYQNFLYPSEPDLRDLLLFLAERLPTDASEDAD-----QPAGDSAIFLRAIGSQIRDQLALPWVPPLLRTPKVQRLQGSALQQAFHSSRLVLP---ELNCRGEPREFQASP--LLLPAPSQVPQLLGRAASLLEHHAIQLCQHVNRDCPGDEDRVRWASRLPSQEDPRAPQQRLHKQLIEHLRQSWGP----LGAPTQVRDLGEMLQAWGAKAMTG--VPKGSRFTHSEKFTFHLEPQVQAAQVADIP---AASQRPEQDTRAAQEEELESLREQLASVNHNIEEVEANMKSLGMNLVQVETECRQSELSVAEQEQALRLKSRTVELLPDGAANLTKLQLVVESSAQRLIHLASQWEKHRVPLLAEYRHLRKLQDCRELESSRRLVEIQELHQSVRAAAEEARRKEEVYKQLVSELETLPKDVS-RLAYTQRILEIVGNIRKQKEEITKILSDTKELQKEINSLSGKLDRTFAVTDELVFKDAKKDDAVRKAYKYLAALHENCSQLIQTIEDTGTIMREVRDLEEQIETEMGKKTLSNLEKICEDYRALRQENAGLLGRVREV-------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9JIG7-1", "uniprot_id": "CCD22_MOUSE", "id": "Q9JIG7-1", "name": "Coiled-coil domain-containing protein 22", "aln": "MEEADRILIHSLRQAGTAVPPEVQTLRAFTTELVVEAVVRCLRVINPDVGSGLSHLLP-PAMSARFRLAMSLAQACMDLGYPLELGYQNFLYPSEPDLRDLLLFLAERLPSDASEDAD-----QPAGDSAIFLRAIGSQIRDQLALPWVPPLLRTPKVQRLQGSALQQPFHSSRLVLP---ELNSSGELWEFQASP--LLLPAPTQVPQLQGRAASLLEHHASQLCQHVNRDCPGDEDRVRWASRVPSQEDSRAPQQRLHKQLIEHLRQSWGP----LGAPTQVRDLGEMLQTWGARAMTG--VPKGSRFTHSEKFTFHLEPQVQAAQVADVP---ATSQRLEQDTRAAQEQELESLREQLASVNHNIEEVEADMKTLGINLVQVETECRQSELSVAEQEQALRLKSRTVELLPDGAANLAKLQLVVESSAQRLIHLASQWEKHRVPLLAEYRHLRRLQDCRELESSRRLAEIQELHHSVRAAAEEARRKEEVYKQLVSELETLPKDVS-RLAYTQRILEIVGNIRKQKEEITKILSDTKELQKEINSLSGKLDRTFAVTDELVFKDAKKDDAVRKAYKYLAALHENCSQLIQTIEDTGTIMREVRDLEEQIETEMGKKTLSNLEKICEDYRALRQENAGLLGRVREA-------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O60826-1", "uniprot_id": "CCD22_HUMAN", "id": "O60826-1", "name": "Coiled-coil domain-containing protein 22", "aln": "MEEADRILIHSLRQAGTAVPPDVQTLRAFTTELVVEAVVRCLRVINPAVGSGLSPLLP-LAMSARFRLAMSLAQACMDLGYPLELGYQNFLYPSEPDLRDLLLFLAERLPTDASEDAD-----QPAGDSAILLRAIGSQIRDQLALPWVPPHLRTPKLQHLQGSALQKPFHASRLVVP---ELSSRGEPREFQASP--LLLPVPTQVPQPVGRVASLLEHHALQLCQQTGRDRPGDEDWVHRTSRLPPQEDTRAQRQRLQKQLTEHLRQSWGL----LGAPIQARDLGELLQAWGAGAKTG--APKGSRFTHSEKFTFHLEPQAQATQVSDVP---ATSRRPEQVTWAAQEQELESLREQLEGVNRSIEEVEADMKTLGVSFVQAESECRHSKLSTAEREQALRLKSRAVELLPDGTANLAKLQLVVENSAQRVIHLAGQWEKHRVPLLAEYRHLRKLQDCRELESSRRLAEIQELHQSVRAAAEEARRKEEVYKQLMSELETLPRDVS-RLAYTQRILEIVGNIRKQKEEITKILSDTKELQKEINSLSGKLDRTFAVTDELVFKDAKKDDAVRKAYKYLAALHENCSQLIQTIEDTGTIMREVRDLEEQIETELGKKTLSNLEKIREDYRALRQENAGLLGRVREA-------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q4V909-1", "uniprot_id": "CCD22_DANRE", "id": "Q4V909-1", "name": "Coiled-coil domain-containing protein 22", "aln": "MEEVDRILIHSLRQAGTDIDEDVQSVKQFTSELIVEAVVRCLRVIDPAVGNGLSHSLP-PGMSARFRLGMSLAQACQDVGFKGEIGYQTFLYSNEPEIRSLFMFLVERLPRESAEASD-----QPAGKSVLLQRAIAAQIKAQLSVPWLPPTCRLPVHRKTQSSGPCHSFHAQPLSLPCSLKVSSRKQPKEVQEYWRNYLLPVTAQPSQPASVPASLLENHISELSAAQEWESEWNSQ--GLLSRLTPEEYRSRKKARLQKRIEEQLRTAAQPRPDTHGATRSTSDLAELLQSFGGASTGGDVLTKGTRFTHTEKFTFTQEPEKAVQQMAAAASALPSSQQSEEDLKAQQEAELSALQQQLQQLSVQMEEVGGGIKQLTVSIQQVTDELQTREVTNAERENSVKIKRQTIDLLPDAENNLLKLQSLVESSSKRVVQLASQWEKHRVPLIDEHRRLKELCSNRESESSRKLSEIKDLHDKIRQSAEEAKKKESLYKQLLTEFETLSKDVS-RSAYTIRILEIVGNIKKQKEEITKILSDTKDLQKEINGLTGKLDRTFAVTDELVFKDAKKDESVRKSYKYLAALHENCTQLIQTIEDTGTIMREIRDLEEQIETENGKRTVSNLEKILEDYKAIRQENSALAAKIREG-------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VVB4-1", "uniprot_id": "CCD22_DROME", "id": "Q9VVB4-1", "name": "Coiled-coil domain-containing protein 22 homolog", "aln": "MDEVDKIIMHQLHQVDATIEP-TDELSDFTPEQVVRAVSGCLAEIRPDLQ--LPRTLPGGAMAQRFGVASSLAQGCKDSGYRGDIGYQTFLYPNAVELRRLLMFLIEQLPRERQGTEDGASKSQTLSHRQLLERKIRKELAQQLKTPWVPQFARSVGNRKLLGCSSLGIEFRPNINLN----------------------------------------------------------------IPSANPEERSKEQQQYLDQQAPNLFQQTSST----------STDLIASVLHKNELDRWG-------QILPDSTLIFVSSEDPAPPLIPTVK-------PPASAEKEEEPSPIQELSDQVQELRVQCENLLAERKAHAVAIAALKQRETKAREEISRIQPTLKLHERTSLVLADSEENLAKLEALLKSTQSKRLTLTQQWQDYRKPLLESLEKLKTAKEAQEVQG---------IRNSIEQLEQELLAKTQQHNELNATLRSASQSLAPRKEYTRRIHEFIGNIRKQRADIYKVLDDTRQLQKQLNVVGAQLQRQFNYTDDLLFQSAKHDLHAKRAYKLLAQLHANCNELVECVSLTGNVTKQIRELEVQIDGEKLKNVLTSLQQITGDIQKFEQHIQELQEQIRAVEQTNAGS", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*:*.*:*::*.*:*..: : .: : **.* :*.** ** * * : *. ** .*: ** :. ****.* * *: ::***.***.. ::* *::** *:** : * *. .. :: * * :: ** **:* * :: ... . : : . .:* : *.:: : :: : ** : . * :: ..: * . : :. . : :. * :*: : . *:: . * : : . . :. : ::::: :: :*.*. ** **: :::.: .: : *: **:.:* **: . .:*: . :* :. ::..:. :* * . :::* : :.: .:.:: * ** ** *::***:**: :* *:*.**::***::* : .:*:* * **:*:*:.**:* .:::** ** ** **.:*:: :. **.: :::*:** **: * *..::.*::* * : :.*. * ::* ", "identical_positions": 134, "similar_positions": 194, "identity": "20.46%" }, { "cls_id": "homologset.agr.MGI:1859609", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9JMD2-1", "uniprot_id": "SMBT1_RAT", "id": "Q9JMD2-1", "name": "Scm-like with four MBT domains protein 1", "aln": "MNGEQQLDADLGSGVEVEEFSWEDYLEETGATTAPYASFKHVDICLQSGFAPGMKLEVALRKDPE-TYWVATVITACEQLLLLRYEGYGEDRKADFWCDIRRAGLYPIGWCQQNKKTLEAPEGIRDKVSDWSAFLQRTLTGACGPPVALLEGLRNGRNPLDLIAPGSRLECQDFRDSVSTWIVTVVENIGGRLKLQYEGLE--RHDGFEHWLYYLDPFLHHIGWAAQQGYELQPPLAIRHLKNEADWQEILARVK-EEE--PLPSYLFKDKQVIRTHEFSINMKLEAVDPWSPFGISPATIAKVFDDKYFLVEIDDLRPEDHAR---RSFVCHANSPGIFPVQWSLKNGLHINPPPGFRSQDFDWADYLKQCGAEAAPQKCFPQSVSEHQFKENMKLEAVNPLFPEEVSIATVTAVRGSYLWLQLEGSKKPVPEFIVSVESMNIFPLGWCETNGHPLSTPRRARGHKLRKIAVVQPEKQILSSRTVHEGLKN-QLNSPHSVMI---NGKYCCPKIYFNHRCFSGPYLNKGRIAELPQCVGPGNCVLVLREVLTLLINAAYKPSRVLRELQLDKDSVWHGCGEVLKAKYKGKSYRATVEIVRTADRVTEFCRQTCIKLECCPNLFGPRMVLDTCSENCSVLTKTKYTHYYGKKKNKRIGRPPGGHSNLSCALKKTSKRRKRRKNIFVHKKKRSSASVDNTPVGSPQGSGGEDEDDADDGDDDSLTEGSTSEQQDELHEESEVSEKKSCSPSPTQSEMSTPLPPDTQTDKREAQTSSLSDGENKPPSPKEIRIEVDERLHLDSNPLKWSVADVVRFIRSTDCAPLARIFLDQEIDGQALLLLTLPTVQECMDLKLGPAIKLCHHIERIKFAFYEQFAN", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9JMD1-1", "uniprot_id": "SMBT1_MOUSE", "id": "Q9JMD1-1", "name": "Scm-like with four MBT domains protein 1", "aln": "MSGEQQLDADLGSGVEVEEFSWEDYLEETGSTTVPYASFKHVDIRLQNGFAPGMKLEVALKNDPE-TYWVATIITACEQLLLLRYEGYGEDRKADFWCDIRKAGLYPIGWCQQNKKTLEAPEGIRDKVSDWNAFLQQTLIGACGPPVSLLEGLRNGRNPLDLIAPGSKLECQDFRDSLSTWLVTVVENIGGRLKLRYEGLE--SRDGFEHWLYYLDPFLHHIGWAAQQGCDLQPPLAIKHLKSEADWQEILAKVK-EEE--PLPSYLFKDKQVIGTHEFSINMKLEAVDPWSPFGISPATIAKVFDDKYFLVEMDDLRPEDHTR---RSFVCHANSPGIFPVQWSLKNGLHINPPPGFRSQDFDWADYLKQCGAEAAPQKCFPQSISEHQFKENMKLEAVNPLFPEEVCIATVTAVRGSYLWLQLEGSKKPVPEFIVSAESMNIFPLGWCETNGHPLSTPRRARGHKLRKIAVVQPEKQILSSRTVHEGLKN-QLNSTHSVMI---NGKYCCPKIYFNHRCFSGPYLNKGRIAELPQCVGPGNCVLVLREVLTLLINAAYKPSRVLRELQLDKDSVWHGCGEVLKAKYKGKSYRATVEIVRTADRVTEFCRQTCIKLECCPNLFGPRMVLDTCSENCSVLTKTKYTHYYGKKKNKRIGRPPGGHSNLSCALKKSSKRRKRRKNIFVHKKKRSSASVDNTPVGSPQGSGGEDEEDADDGDEDSLTEGSTSEQQEELQEESEVSEKKSSSSSPTQSETPTPLPPDTQTNKRDAQTSSVSDDENKPPSPKEIRIEVDERLHLDSNPLKWSVADVVRFIRSTDCAPLARIFLDQEIDGQALLLLTLPTVQECMDLKLGPAIKLCHHIERIKFAFYEQFAN", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9UHJ3-1", "uniprot_id": "SMBT1_HUMAN", "id": "Q9UHJ3-1", "name": "Scm-like with four MBT domains protein 1", "aln": "MNGEQQLDADAGSGMEEVELSWEDYLEETGSTAVPYGSFKHVDTRLQNGFAPGMKLEVAVRTDPE-TYWVATVITTCEQLLLLRYDGYGEDRRADFWCDIRKADLYPIGWCEQNKKTLEAPEGIRDKVSDWDEFLRQTLIGACSPPVPLLEGLRNGRNPLDLIAPGSRLECQAFQDSLSTWIVTVVENIGGRLKLRYEGLE--SSDNYEHWLYYLDPFLHHVGWAAQQGYELQPPSAIRHLKNEAEWQEILAKVK-EEEEEPLPSYLFKDKQVIGIHTFSVNMKLEAVDPWSPFGISPATVVKVFDEKYFLVEMDDLRPENHAR---RSFVCHADSPGIFPVQWSLKNGLHISPPPGYPSQDFDWADYLKQCGAEAAPQRCFPPLISEHEFKENMKLEAVNPILPEEVCVATITAVRGSYLWLQLEGSKKPIPECIVSVESMDIFPLGWCETNGHPLSTPRRARVYKQRKIAVVQPEKQVPSSRTVHEGLRNQELNSTESVMI---NGKYCCPKIYFNHRCFSGPYLNKGRIAELPQCVGPGNCVLVLREVLTLLINAAYKPSRVLRELQLDKDSVWHGCGEVLKAKYKGKSYRATVEIVKTADRVTEFCRQTCIKLECCPNLFGPRMVLDKCSENCSVLTKTKYTHYYGKKKNKRIGRPPGGHSNLACALKKASKRRKRRKNVFVHKKKRSSASVDNTPAGSPQGSGGEDEDDPDEGDDDSLSEGSTSEQQDELQEESEMSEKKSCSSSPTQSEISTSLPPDRQRRKRELRTFSFSDDENKPPSPKEIRIEVAERLHLDSNPLKWSVADVVRFIRSTDCAPLARIFLDQEIDGQALLLLTLPTVQECMDLKLGPAIKLCHHIERIKFAFYEQFAN", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9PVD7-1", "uniprot_id": "A0A8M9PVD7_DANRE", "id": "A0A8M9PVD7-1", "name": "", "aln": "MS-LEALESDADSGQDVSEFNWDDYLEESGALSVPHHAFKHVDQGLETGLTPGMKLEVCVRTESESVYWVATIITTCGQLLLLRYEGYQDDRRADFWCDIMTADLHPIGWSKQQGRMMKPPEGVREKHQDWEALLEKALAESCSVPASLLEGAQRGCNPIDLLSPGLNVELVDHQDAGVVWSAVIEKNIGGRLRLRYAGTDGLPENQSITWVFYLDPLLHLSGWAQEHNCTLRPPAALLPLRTEPEWEEVKKSISSQEQDSSISEEFYRDRSAITPHCFTEGMKLEAVDPAAPFTISPATVAKVFNEQFFLVLMDDMRDEAQKEGGAHSFLCHRDSPGIFPTQWSLKNGVKLSPPPGFQGQDFDWADYLKQCEAEAAPQQCFPPDPSDQCIKESMMLEAVNPICPENIHVATVTKVKGQHMWIRLEGLKQAMPEIIVHTDSMDIFPVSWCETNGYPLLHPCKPRVEKQRKVAVVQPEKHRVPSKDSSPDTTKQHMNSSQAEMAGQANGKYCCPKIYFNHRCFSGPYLNKGRIAELPQCVGPGNCVLVLKEVLTLLINSAYKPSRVLRELQLDQEGRWQGHGETLKAKYKGKSYRATVEIVRTADQVADFCRKTCIKLECCPNLFGPRMVLEHCSENCSVLTKTKYTYYYGKKKSRRVGRPPGGHSNLEGGVKRRGRRRKRRKQLFVHKKRRSSASVDNTPAGSPQGSG--DEEDLDE--DDSLSEDTGSEMQDELMDDSEYSEKKSQPPTPSPSPPETPRP---TRRRRKARSPSCSDDENRPPSPKSPRTEVPQKLCLDSSPLEWSVTDVVRFIRTTDCAPLARIFMDQEIDGQALLLLNLPTVQECMDLKLGPAIKLCHHIERVKLAFYQQFAS", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*. : *::* .** : *:.*:*****:*: :.*: :***** *:.*::*******.::.:.* .*****:**:* *******:** :**:******* *.*:****.:*: : ::.***:*:* .**. :*.::* :*. *..**** :.* **:**::** .:* .:*: .* ..: :******:*:* * : : *::****:** *** ::. *:** *: *:.*.:*:*: :. :*: .:.. :::*:..* * *: .******** :** *****:.***::::*** :**:* * : . :**:** :******.*******:::.****: .************ ******:*** *:: :**.* ******: **:: :**:* *:*.::*::*** *:.:** ** .:**:***:.******:** * :.* * **:*******: .*: . : .:**..: * ******************************************:********:**************::. *:* **.*****************:***:*::***:******************: **************:******.:*:********** .:*: .:******::*****:**********.******* **:* *: :***:*.: ** *:** ::** ***** ..:*: * *. * :*. :: * **.**:*****. * ** ::* ***.**:***:*******:**********:************.************************:*:***:***.", "identical_positions": 518, "similar_positions": 219, "identity": "59.13%" }, { "cls_id": "homologset.agr.MGI:1859610", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "G3V8Z3-1", "uniprot_id": "G3V8Z3_RAT", "id": "G3V8Z3-1", "name": "G-patch domain and KOW motifs-containing protein", "aln": "MAG----------RES--PPPAAASTAPISFGFTRTSVRRRLADLGDSEGQAPEKKDFLATVEGRELQSVNPPEAPKELVIPLIQ-NGSRRQLLSKNPKPS----ETSTVLTSDGVLSQAVKELIE----ESKKSLEERENAG-VDPTLTIPMIQKGCTPIGEGTYSEPQAETVPE---EADYEAVPVEAYGLAMLRGMGWKPGKGIGNTFSQVVKPRVNSIRPKGLGLGANLMETQALASTGSHHPPRPDGDREKDKEGQPQGLMHGGAVVVLSGPYRGLYGKVEGLDPDNVRAMVRLAVGNRVVNVSEYCLRPVSQQEFDSHTSKPGHVSKTSTE-------QQHRATGTASSVKALQNQEDSKRRQKDSE--KKRKH---SPDRRDGPVPKTEKAAPRNKHWLHRDLRVRFIDKVHKGGRYYNTKMTIEDVLSPGTCVCRTDEGRVLEGVKEGMLETLVPRGEGHRVMVVLG--PHAGKVGLLLRRDRAQSHAMVQLGR-ENQVVELHYDAICQYMGPGDSDED----------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q56A08-1", "uniprot_id": "GPKOW_MOUSE", "id": "Q56A08-1", "name": "G-patch domain and KOW motifs-containing protein", "aln": "MAG----------RES--PPPSAPSMAPISFGFTRTSVRRRLADLGDSERQAPEEKDFLATVEGRKLQSVNPPEAPKELVIPLIQ-NGSRRQPLSKNPKPSS---ETSTVLMSDGVLSQAVKELIE----ESKKSLEERENAG-VDPTLTIPMIQKGCTPIEEGSDSEPQAETVPE---EADYEAVPVEAYGLAMLRGMGWKPGKGIGNTFSQVVKPRVNSIRPKGLGLGANRMEAQDLASVGSHHPPRPDGDRENDKEGQPQGLMHGRAVVVLSGPYRGLYGKVEGLDPDNVRAMVRLAVGNRIVTVSEYCLRPVSQQEFDSHTSKPGHVSQTSTE-------QQNRATGTASSLKAAQNQEDSKRRQKGSE--KKRKH---SPDRQDGPVPKTEKAAPRNKHWLHRDLRVRFIDKLHKSGRYYNTKMTIEDVLSPDTCVCRTDEGRVLEDVREDMLETLIPKGEGHRVMVVLG--PHAGKVGLLRSRDRAQSHALVQLRR-ENQVVELHYNAICQYMGPGDSDED----------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q92917-1", "uniprot_id": "GPKOW_HUMAN", "id": "Q92917-1", "name": "G-patch domain and KOW motifs-containing protein", "aln": "MAD----------SKEGVLPLTAASTAPISFGFTRTSARRRLADSGDGAGPSPEEKDFLKTVEGRELQSVKPQEAPKELVIPLIQ-NGHRRQPPARPPGPS-----TDTGALADGVVSQAVKELIA----ESKKSLEERENAG-VDPTLAIPMIQKGCTPSGEGADSEPRAETVPE---EANYEAVPVEAYGLAMLRGMGWKPGEGIGRTFNQVVKPRVNSLRPKGLGLGANLTEAQALTPTGPSRMPRPDEEQEKDKEDQPQGLVPGGAVVVLSGPHRGLYGKVEGLDPDNVRAMVRLAVGSRVVTVSEYYLRPVSQQEFDKNT--------LDLR-------QQN---GTASSRKTLWNQELYIQ-QDNSE--RKRKH---LPDRQDGPAAKSEKAAPRSQHWLHRDLRVRFVDNMYKGGQYYNTKMIIEDVLSPDTCVCRTDEGRVLEGLREDMLETLVPKAEGDRVMVVLG--PQTGRVGHLLSRDRARSRALVQLPR-ENQVVELHYDAICQYMGPSDTDDD----------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q90X38-1", "uniprot_id": "GPKOW_DANRE", "id": "Q90X38-1", "name": "G-patch domain and KOW motifs-containing protein", "aln": "MASPERYQERESLKKDISQDDGGKKAAPISFGFSKTLIKVKSGK--------AEERDYLVEVEGKELKGTKPVEKPKELIIPLIHKNRWYRQDAERADKTSEEKTEEPSQVKQDTVESQAVKELIE----ESQKYQDRWKNGPQSDPNFAIPLLMQNQVPDGFEDGDKVNVDLRPESSTEADYERVPVEAYGLAMLKGMGWKQEEGIGRTFKQDVKPIEHQLRPKGLGLGADRSAIKDLEPGVPKRPPKPGD--EKGKEEEALVLGPGGCVQVLAGAHKDLYGKIEGVDPDNGRVVVKLAIGGKTVTIIQHSIKLVTRKEYDKYSKDLSRLSKAHKDKEREKEREQKREQEQRLNGKDERGKTDRSREKDRDQ--KKRKHRESSTDREKPPPAKESRSSPPAPSWLQRDLRVRFIDKAFKGGKYYNSKMRVEDVLTPHTCVCRTEEGRMLDDIRQKMLETIVPKNDSDYIMVVLG--EHRGQVGRILKRDREKCRAMVQLDRYEERVFTLDYDTICHYVGGTDH-------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q02521-1", "uniprot_id": "SPP2_YEAST", "id": "Q02521-1", "name": "Pre-mRNA-splicing factor SPP2", "aln": "-------------------------MSKFSLKLGSKTLKKNISK---------------KTKKKNSLQKAN-----------LFDWDDAETASLSHKPQSK--------------IKIQSIDKFDL----DEESSSKKK-------------LVIKLSENADTKKNDAPLVEYVTE----KEYNEVPVEEFGDALLRGMGWESD---------------------------------------SEQDSKGDKTQSRNKD----------------------VSNVSQIHPDGLGIGAKLN---KAINVEEASFMPVVK-------------------------------------------IDKITGTKVDDD--KKNKS-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "Q9VES0-1", "uniprot_id": "Q9VES0_DROME", "id": "Q9VES0-1", "name": "Spp2/MOS2 G-patch domain-containing protein", "aln": "-----------------------MEAKKISFGFSKLSKKPNILP--SKQPKEESKVELIKCLEGNEIMPVDEKVEAAPLTIKMIGMQKTSSALASLMRRRAVLLGEEEPDPEEVTPVAQSIAEVTAGGPTESLEQRAARELISAIQNNGAEGLDDQKLVLPALSADELPLDGAKEAT--LDDYDNIPIQQFGLAMLRGMGWVDPPPKKKGSGPIDDAP--FLRPKGMGLG-------------ADKALKPKALLVQPEKNEVLEIKKQAYVRILGGKQKDQYGQIQGFDDHAGRVIVKMAIGGAKEAFNEFLCQPVSRKEYSQYGKCINTAKYEEFKKNENEHGQIIVKQENPSGRRDRDRREEIRSDRDEAQNQKSSKPGDQRSSKEDYRMKCKEEDKRSYKYEDKKTYKDEHRRTYKDERKSYKEAKSNKEEVDREKKYVRSGSSSVSKREERERRRSPSPRGRSPSKSKREDRDQKRSQSPRSTRRTKSSSDEADDTGESTESDSDSAYERRKHKKKSSSHKSRKHSKKSKNKSRKADNDSSLESDDSLGENHRRHHSKHKKKTKRSKHVRSRTRSRSRDRQ", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :*: : : . : ..: .. :: : *:: :. :. . : : . :*: :*:: :* *:*:**** . : : . :. .::. .. . .:: . : * : : : :. * ", "identical_positions": 13, "similar_positions": 55, "identity": "2.22%" }, { "cls_id": "homologset.agr.MGI:1859615", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q2YDU3-1", "uniprot_id": "OTUD5_RAT", "id": "Q2YDU3-1", "name": "OTU domain-containing protein 5", "aln": "MTILPKKKPPPPDADPANEPPPPGPLPPAPRRGGGVGVGGGGTGVGG--------GERDRDSGVVGARPRASPPPQGPLPGPPGALHRWALAVPPGAVAGPRPQQASPPPCGGPGGPGGGPGDALGATTAGVGAAGVVVGVGGPVGVGGCCSGPGHSKRRRQAP----------------------GVGAVGGASPEREEVGAGYNSEDEYEAAAARIEAMDPATVEQQEHWFEKALRDKKGFIIKQMKEDGACLFRAVADQVYGDQDMHEVVRKHCMDYLMKNADYFSNYVTEDFTTYINRKRKNNCHGNHIEMQAMAEMYNRPVEVYQYST-----EPINTFHG-IHQNEDEPIRVSYHRNIHYNSVVNPNKATIGVGLGLPSFKPGFAEQSLMKNAIKTSEESWIEQQMLEDKKRATDWEATNEAIEEQVARESYLQWLRDQEKQARQVRGPSQPRKASATCSSATAAASSG----------------------------------------LEEWTSRSPRQR----------------------SSASSPEHPE-LHAELGIKPPSPGTVLALAK------------------------PPSPCAPGTSSQFSAGADRATSP-LVSLYP-----------ALECRALIQQMSPSAFGLNDWDDDEILASVLAVSQQEYLDSMKKNKVHRDPPPDKS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q3U2S4-1", "uniprot_id": "OTUD5_MOUSE", "id": "Q3U2S4-1", "name": "OTU domain-containing protein 5", "aln": "MTILPKKKPPPPDADPANEPPPPGPLPPAPRRGAGVGVGGGGTGVGG--------GERDRDSGVVGARPRASPPPQGPLPGPPGALHRWALAVPPGAVAGPRPQQASPPPCGGPGGPGGGPGDALGATTAGVGAAGVVVGVGGTVGVGGCCSGPGHSKRRRQAP----------------------GVGAVGGASPEREEVGAGYNSEDEYEAAAARIEAMDPATVEQQEHWFEKALRDKKGFIIKQMKEDGACLFRAVADQVYGDQDMHEVVRKHCMDYLMKNADYFSNYVTEDFTTYINRKRKNNCHGNHIEMQAMAEMYNRPVEVYQYST-----EPINTFHG-IHQNEDEPIRVSYHRNIHYNSVVNPNKATIGVGLGLPSFKPGFAEQSLMKNAIKTSEESWIEQQMLEDKKRATDWEATNEAIEEQVARESYLQWLRDQEKQARQVRGPSQPRKASATCSSATAAASSG----------------------------------------LEEWTSRSPRQR----------------------SSASSPEHPE-LHAELGIKPPSPGTVLALAK------------------------PPSPCAPGTSSQFSAGGDRATSP-LVSLYP-----------ALECRALIQQMSPSAFGLNDWDDDEILASVLAVSQQEYLDSMKKNKVHREPPPDKS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q96G74-1", "uniprot_id": "OTUD5_HUMAN", "id": "Q96G74-1", "name": "OTU domain-containing protein 5", "aln": "MTILPKKKPPPPDADPANEPPPPGPMPPAPRRGGGVGVGGGGTGVGG--------GDRDRDSGVVGARPRASPPPQGPLPGPPGALHRWALAVPPGAVAGPRPQQASPPPCGGPGGPGGGPGDALGAAAAGVGAAGVVVGVGGAVGVGGCCSGPGHSKRRRQAP----------------------GVGAVGGGSPEREEVGAGYNSEDEYEAAAARIEAMDPATVEQQEHWFEKALRDKKGFIIKQMKEDGACLFRAVADQVYGDQDMHEVVRKHCMDYLMKNADYFSNYVTEDFTTYINRKRKNNCHGNHIEMQAMAEMYNRPVEVYQYSTGTSAVEPINTFHG-IHQNEDEPIRVSYHRNIHYNSVVNPNKATIGVGLGLPSFKPGFAEQSLMKNAIKTSEESWIEQQMLEDKKRATDWEATNEAIEEQVARESYLQWLRDQEKQARQVRGPSQPRKASATCSSATAAASSG----------------------------------------LEEWTSRSPRQR----------------------SSASSPEHPE-LHAELGMKPPSPGTVLALAK------------------------PPSPCAPGTSSQFSAGADRATSP-LVSLYP-----------ALECRALIQQMSPSAFGLNDWDDDEILASVLAVSQQEYLDSMKKNKVHRDPPPDKS", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q08BW0-1", "uniprot_id": "OTU5A_DANRE", "id": "Q08BW0-1", "name": "OTU domain-containing protein 5-A", "aln": "MTILPKKKP--------NSSVGVSDHPDDPDRRTGSDPHQHQHQHSH--------GVRP------GARPRASPPPWSYQAAPPASRE------DRRTESSSRPQQASPPPVG--AGSSGGPGDATGMACVSGNRAELSGGVGCGGGMGGCCSGPGLSKRRRQATCSGGVAGGGTGPGAAGGGGGGGGGGGVGGPSPEQEE-GAGYNSEDEYEN-ASRLQSEDPATVEQQEHWFEKALQEKKGFVIKKMKEDGACLFRAVADQVYGDQDMHEVVRKHCMDYLMKNADYFSNYVTEDFTTYINRKRKNNCHGNHIEMQAMAEMYNRPVEVYQSGT-----EPINTFHG-IHQNNDEPIRVSYHRNIHYNSVVNPNKATIGVGLGLPAFKPGFADQSLMKNAIKTSEESWIEQQMLEDKKRATDWEATNEAIEEQVARESYLQWLRDQEKQAR------QPRKASATCSSATAAASSG----------------------------------------LEEWNARSPRQR----------------------SSAPSPEIPDPAHSDTAAKPPSPAGALALSK------------------------PPSPCAPGPSNQACVGPDRPTSSSLVSLYP-----------ALGYRAIMQEMSPTAFGLTDWEDDEILASVLAVSQQEYLDSMKKNAMHREPSPDSS", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VTK7-1", "uniprot_id": "Q9VTK7_DROME", "id": "Q9VTK7-1", "name": "ubiquitinyl hydrolase 1", "aln": "MTIKPVSAPPSAKRVAGNVDPDNKEAQVVVVEQSVVSQTHNHAHNHRNVVIDGQSPQRRGEVYDELARTHRCSPHKSTRSKRREHHEAHAHLYKRDRLEREKLVHPTAAAGSGAPGVSGSKCNSPPSTSTSGSSSPSAVGRNSPEHLGLGCTTVPTAQVQMSTS------------------------TAAANLLKTVEETFSGYNSGDEHHQPKERLIP--VEEWQRRDLEFAKCME-QRGYELKPVEEDGACLFRSISLQIYGDEEMHDVIRQHTMDYIHENREYFGQFVTEDINSYIQRKRARDAHGNHIEIQAISEIYSRTVEVYCYQS-----NPINIFNSEQSQAGYPPLRLSYQRGSHYNAILDPYNATVGVGLGLAGYKP----EIQTKEAVRLSEQLEIEQTMFEDKLKTTDWEATNEAIEEQIARESYLQWCRENTQRSRNSNTAAGSATSSTVTSAEALTDSDASPSKYSACGGTGSSGNPPVALTSGSGGDGAGPAFSLSPKTLNQFSHKLPQEVNELGGYDSDATDMSSTSSVGHSGGSSSPSTAASQRSGKGSKSQRRATALRKKRRHETRETTLASKSAEALEAPLRKSPKRDSAPSVARADTPEAEQRPSTSKQSSHSPQKNVDSKSPTEQSYSSFYQELLEASYANEGANESEMLQQAIQMSTRDYMEDQKRKFLFGP------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*** * . * * . . * **.: ..* . . . : :.:... . * .*. :: : .. . : * . :* *: :: : .:. .... ** :**** **:. *: . :::: * *.:. ::*: :* ::********::: *:***::**:*:*:* ***: :* :**.::****:.:**:*** .:.******:**::*:*.*.**** : :*** *:. * *:*:**:*. ***::::* :**:******..:** : *:*:: **: *** *:*** ::*************:******** *:: :::* . .:*:. *: : : *.. *:::. : *:: ..:.**. . :: . *. . .* : * .**. : :: .*. * :. :: *:: :::. . ::.*:* ..: :* ::*::. *:: :. ", "identical_positions": 153, "similar_positions": 182, "identity": "21.83%" }, { "cls_id": "homologset.agr.MGI:1859616", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8VD04-1", "uniprot_id": "GRAP1_MOUSE", "id": "Q8VD04-1", "name": "GRIP1-associated protein 1", "aln": "MAQALSEEEFQRMQTQLLELRTNNYQLSDELRKNGVELSSLRQKVAYLDKEFSKAQKALSKSKKAQEVEVLLSENEMLQAKLHSQEEDFRLQNSTLMAEFSKLCSQLEQLELENRQLKEG--VPGA----AGAHVDGELLRLQAENTALQKNMAALQERYGKEAVRPSAVGEGQG------DPPGDVLPTPLAP------------------MPLAEVELKWEMEREEKKLLWEQLQGLESSKQAETSRLQEELAKLSEKLKKKQESFCRLQTEKETLFNDSRNKIEELQQRKEADLKAQLARTQKLQQELEAANQSLAELRDQRQGERLEHAAALRALQD-------------------------------QIQTAKTQELNMLREQTSELASELQHRQAEYEELMGQKDDLNSQLQESLRANSRLLEQLQEIGQEKEQLTQDLQEARKSAEKRKVMLDELAMETLQEKSQHKEELGAVRLRHEKELLGVRARYERELRELHEDKKRQEEELRGQIREEKARTRELENLQHTVEELQAQVHSMDGAKGWFERRLKEAEESLQQQQQEQEETLKLCREEHAAELKGKDEELQNVREQLQQAQEERDGHVKTISNLKQEVKDTVDGQRILEKKGSAVLKDLKRQLHLERKRADKLQERLQEILTNSKSRTGLEELVLSEMNSPSRT-QTGDSSSVSSFSYREILKEKESSAIPARSLSSSPQAQPPRPAELSDEEVAELFQRLAETQQEKWMLEEKVKHLEVSSASMAEDLCRKSAIIETYVMDSRIDVS-----VAAGHTDRSGLGSVLRDLVKPGDENLREMNKKLQNMLEEQLTKNMHLHKDMEVLSQEIVRLSKECVGSPDPDLEPGEAN", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9JHZ4-1", "uniprot_id": "GRAP1_RAT", "id": "Q9JHZ4-1", "name": "GRIP1-associated protein 1", "aln": "MAQALSEEEFQRMQTQLLELRTNNYQLSDELRKNGVELSSLRQKVAYLDKEFSKAQKALSKSKKAQEVEVLLSEKEMLQAKLHSQEEDFRLQNSTLMAEFSKLCSQLEQLELENRQLKEG--VPGA----AGPHVDGELLRLQAENTALQKNMAALQERYGKEAVRPSAVSEGQG------DPPGDVLPISLSP------------------MPLAEVELKWEMEREEKKLLWEQLQGLESSKQAETSRLQEELAKLSEKLKKKQESFCRLQTEKETLFNDSRNKIEELQQRKEADLKAQLARTQKLQQELEAANQSLAELRDQRQGERLEHAAALRALQDQVSSQSADAQEQVEGLLAENNALRTSLAALEQIQTAKTQELNMLREQNTELAAELKHRQADYEELMGQKDDLNSQLQESLRANSRLLEQLQEMGQEKEQLIQDLQEARKSAEKRKVMLDELAMETLQEKSQHKEELGAVRLRHEKEMLGVRARYERELRELHEDKKRQEEELRGQIREEKARTRELENLQHTVEELQAQVHSMDGAKGWFERRLKEAEESLLQQEQEQEETLKQCREQHAAELKGKEEELQNVRDQLQQAQEERDGHVKTISNLKQEVKDTVDGQRILEKKGSAVLKDLKRQLHLERKRADKLQERLQEILTNSKSRTGLEELVLSEMNSPSRT-QTGDSSSVSSFSYREILKEKESSAIPARSLSSSPQAQPPRPAELSDEEVAELFQRLAETQQEKWMLEEKVKHLEVSSASMAEDLCRKSAIIETYVMDSRIDVS-----VAAGHTDRSGLGSVLRDLVKPGDENLREMNKKLQNMLEEQLTKNMHLHKDMEVLSQEIVRLSKECVGSPDPDLEPGEAN", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q4V328-1", "uniprot_id": "GRAP1_HUMAN", "id": "Q4V328-1", "name": "GRIP1-associated protein 1", "aln": "MAQALSEEEFQRMQAQLLELRTNNYQLSDELRKNGVELTSLRQKVAYLDKEFSKAQKALSKSKKAQEVEVLLSENEMLQAKLHSQEEDFRLQNSTLMAEFSKLCSQMEQLEQENQQLKEG--AAGAGVAQAGPLVDGELLRLQAENTALQKNVAALQERYGKEAGKFSAVSEGQG------DPPGGLAPTVLAP------------------MPLAEVELKWEMEKEEKRLLWEQLQGLESSKQAETSRLQEELAKLSEKLKKKQESFCRLQTEKETLFNDSRNKIEELQQRKEADHKAQLARTQKLQQELEAANQSLAELRDQRQGERLEHAAALRALQDQVSIQSADAQEQVEGLLAENNALRTSLAALEQIQTAKTQELNMLREQTTGLAAELQQQQAEYEDLMGQKDDLNSQLQESLRANSRLLEQLQEIGQEKEQLTQELQEARKSAEKRKAMLDELAMETLQEKSQHKEELGAVRLRHEKEVLGVRARYERELRELHEDKKRQEEELRGQIREEKARTRELETLQQTVEELQAQVHSMDGAKGWFERRLKEAEESLQQQQQEQEEALKQCREQHAAELKGKEEELQDVRDQLEQAQEERDCHLKTISSLKQEVKDTVDGQRILEKKGSAALKDLKRQLHLERKRADKLQERLQDILTNSKSRSGLEELVLSEMNSPSRT-QTGDSSSISSFSYREILREKESSAVPARSLSSSPQAQPPRPAELSDEEVAELFQRLAETQQEKWMLEEKVKHLEVSSASMAEDLCRKSAIIETYVMDSRIDVS-----VAAGHTDRSGLGSVLRDLVKPGDENLREMNKKLQNMLEEQLTKNMHLHKDMEVLSQEIVRLSKECVGPPDPDLEPGETS", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "B0UYE9-1", "uniprot_id": "B0UYE9_DANRE", "id": "B0UYE9-1", "name": "", "aln": "MAQALSEEEFHRMQAQLLELRTQNYQLSDELRKNTAELNSVRQKISNLEKDYVKAQKALNKSKKAQEVDALINENKMLQGKLHSQEDDFRLQNSTLMQELSKLCSQIELLESENQGLRDGKGLEKPACSPASAPVDAELLRLQAENSALQKKLTALQEIADGNGGKAALVDGSTGTNGVQSDASGHSNDSSASGNDQTDQADLQSVKAEKRENEVREVALKLQTEMEEKCLLREQLQTLEISKQAEITKLQEESAKLTDKLKKKQESFQRLQVEKEVLYNDSRTKIDEIQQRKEEELKSINLRVQKLQTDLMAANQNVGELKEQLQSKQKEHEMAIHALKDQVACQSAVSQEQVEGMLSENDALRTNLAALEQIQTVKTQELNLLREQNLALNAELQQRRTDQESFLAQRDDLNSQLQESNRANSRLLEQLTELGLEKDKLLQDLEEARKTADKRKVMLDELAIETAQEKSRHKEELSNVRLQHEKEVLSIRARYEKELRGLHEEKNRIEEEIRSQLRDERARTKELEGLQPYVEELKAQVQSMEGTKGWFERRLKEAEETMERSKLDHAEEIKRLQKDHTLQLEAKAAEVDAVQQQVTEMEKEREDLNNTIGKLKQEIKDTVDGQRILEKKGSSALKDLKRQLHLERKRADKLQERLQEILTNTKTRTGLEELVLSEISSPSRTQQTGDSSSISSFSYRDIMKDGASAPSTNKSNTSSPQSQ--RPADLSDDEVSELFQRLAEVQQEKWMLEEKVKHLEVSCASMADDICKKSAIIETYVMDSRRDVSGGVGLAHSAQPDRGGLSSVLRDLVKPGDENLREMNKKLQNMLEEQLTKNMHLQKDLEVLSQEIVRLSKDTTPAENSKTTG----", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "**********:***:*******:*********** .**.*:***:: *:*:: ******.********:.*:.*::***.******:********** *:******:* ** **: *::* . *.. **.*********:****:::**** . :. : : *. . * *..* : : ** ** : * *** ** **** ** ***** ::**** ***::********* ***.***.*:****.**:*:***** : *: *.**** :* ****.:.**::* *.:: ** *::**:* ****.******:****. * :**:::::: *.::.*:********** ********** *:* **::* *:*:****:*:***.******:** ****:*****. ***:****:*.:*****:*** ***:*:* ***:*.*:*:*:***:*** ** ****:***:**:*:*************:: :.: :: * :* :::*: :*:.* *:: *::*: : ::**: :**..****:***************:.***********************:****:*:*:*********:.***** *******:******:*::: *:. . :* :****:* ***:***:**:********.*****************.****:*:*:************* *** . :.:.**.**.***********************************:**:************: . . :.. ", "identical_positions": 522, "similar_positions": 183, "identity": "59.79%" }, { "cls_id": "homologset.agr.MGI:1859617", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9JIG4-1", "uniprot_id": "PPR3F_MOUSE", "id": "Q9JIG4-1", "name": "Protein phosphatase 1 regulatory subunit 3F", "aln": "MARTAPVEPPLRHPAPPSPAAGEPRASAEAAVAPRRVLFADEALGLPLAQLRRYRPWGGPGAGKMAAATGQDG-GGGG-ADEEDDGEDGDEGEEEEEAFPDPSPPCPVPAGGGFYLVP-------TFSLPPALGRLERLGRVMVELEALLPPPGAVP----------GGSGVWVPGGRPPVVRGLVRVLNRSFEKAVHVRAS-HDGWATFCDHPARYVPRSPPGAGVGGTGAGDPLLDPGLGLGPGQMSASSPDDGGCT-----------DRFAFQLPFAEGASDGARLDFVVRYETPEGTFWANNHGRNYTVLLRIAPAPTPTDAEGLPQQQQLQQLEPQPECQGPVEAEARQLKSCMKPVR---RRPFEEEPRMRSADDN--TLAEHPDVRESLGPLLAPTPLRPWPQMTLQVPEVMLTSNPQEEGDIPRSNPPVAFTEVRQAPAIRILPAT--CGLGGPPRDQASGPDASDRAAGSFLEPTQQQVEAAWESGGGRKAPMVGALTDEPARGLEIVSGLDELLGEDTIDQELEQLYLSHLSRLRAVAAAG----GGEG-----TSPTHALGILTDRDLILKWPGPERALNSALAEEITLHYARLGCGVELIKDTEDPDDEGEGEDGLSITPSSPEGGSPKESPPEILSGARSVIATMGDVWVPWAERSSSRCDSPVVLGTQGQFTENPEKGMGKDTKSLHLNRVIVGMSKSPGEAGTESQMEELPTERESSWVPSSEKELPLPVQQE-QSPALLGPTGTEVCLSSVAKPHVNSQEEEGGSLNLESPKRSPMPAAP--AECACGLAPQLWGPLTQTLGVLAGLVMVPVALNSGVSLLVLVLCLSLAWFS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6ZSY5-1", "uniprot_id": "PPR3F_HUMAN", "id": "Q6ZSY5-1", "name": "Protein phosphatase 1 regulatory subunit 3F", "aln": "MARTAPVEPPLRHSAPPSPAAGEPRTSVEAAVAPRRVLFADEALGLPLAQLRRYRPWGGPGAGKMAAAAGQDG-GGGGGADEDDDGEDGDEGEEEEEACPEPSPLCPVPAGGGFYLVP-------TFSLPPAPGRLERLGRVMVELEALLPPPGAVP----------GGAGVWVPGGRPPVLRGLVRVLNRSFEKAVHVRAS-HDGWASFCDHPARYVPRSPPWAGAGGTGAGDPILDPGLGLGPGQASASSPDDGGRT-----------DRFAFQLPFAEGAGDGARLDFVVRYETPEGTFWANNHGRNYTVLLRIAPAPTPTDAEGLPQQQQLPQLEPQPECQGPVEAEARQLKSCMKPVR---RRPAEEELKTKNMDDNTFAMAEHPDVQESVGPLVAPTPLRPWPQMTLQVSDVPMTGNPAEEGDVPRSSPPVAFTEVLQAPAIRIPPSSPLCGLGGSPRDQASGPDASEGATGPFLEPSQQQAEATWG------------VSSENGGGLEAVSGSEELLGEDTIDQELEQLYLSHLSRLRAAVAAGGAGGGGEGSTDGGMSPSHPLGILTDRDLILKWPGPERALNSALAEEITLHYARLGRGVELIKDTEDPDDEGEGEEGLSVTPSSPEGDSPKESPPEILSGARSVVATMGDVWLPWAEGSG--CDGPVVLGTEGQFIGDPEKGMGKDTSSLHMNRVIAGVTESLGEAGTEAQIEVT-SEWAGSLDPISGKEPASPVLLQGQNPTLLSPLGAEVCLSSVARPHVSSQDEKDAGPSLEPPKKSPTLAVP--AECVCALPPQLRGPLTQTLGVLAGLVVVPVALNSGVSLLVLALCLSLAWFS", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P28006-1", "uniprot_id": "GAC1_YEAST", "id": "P28006-1", "name": "Serine/threonine-protein phosphatase 1 regulatory subunit GAC1", "aln": "MVIQTATTLSPAKARPSFPHNDLIKSMSDSLIS--RPTHPPIRKLKSSLKISHPEPISRSKSEIFCTSPEKNVRFAIELTTVKRFDKNAEPSSISNENSPTLSPVDSNTAADDVQLFNNEDCWFNDSSLVTNLLKNEKKFRYMNSLNNMFKLDLYDSEDEDDIDEHINSQAEYGYTYNSLSTRGKTSENKSATSSLATQATN-ICDWKLHCTDLVPFKIAPPLFTKT--LSASDLQGQLTKYLNGQNVKLHSLTQLGDD-----------SSKITGLVYVKNLSFEKYLEIKFTFNSWRDIHYVTAN-FNRTINSNVDEFKFTIDLNSLKYILLIKRIITMEKNTS--SCPLNIELCCRYDVN---NETYYDNNNGKNYHLFMTTFKKGGETKEKIPVVVEPASQTDAAMSPKEMKARFVSSNPTLSRFLPQSRKFSEDTDYYNTSPLKHLYHNDTTSWVK-PKRLNVVLDKLENATPPPPSSALANDTARTGKITKDKNNVLAPPTASNSIDLPILGSQHQSLYSGSSSYSSSSSSISSSLSFASSNNSS---TNSSS-----ASCSFPLTELDNFDYANLYEPNDTFTTANLFNHSLNSLMPEISTPSFFGGFRNENTINNNDSKNLVTSLEDSYEDKQSVITDTTMDENNKTSTINNSTDTLIKPSK----------ENGTVKENKSSANSTSAPSSSQNRASTILN-----DHSNGKSDLKYVNYQSLLDSHCFYNHPSSPNLQSTSFSSAAPFSGISQASDIFDYENEDSDSNQIAGEIDNNSFPPHFYLDEDDKSACLSDDALIDHHRNTNPFINTFSSSPPILSQEVDRWRL----------", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "Q06216-1", "uniprot_id": "PIG1_YEAST", "id": "Q06216-1", "name": "Serine/threonine-protein phosphatase 1 regulatory subunit PIG1", "aln": "--------MPYSHGKKLKPSLKLAKTISTSSFVS----------STTSNSFSPLEDSTSASSSTSSSSSGKSVRFAAHLYTVKKFNTKLAPISISEKAASNLTRNLHNNAIP-----------------LTFPFIGGEDHRYSLDILDYSDLEYDNKD--------VEYDNESDVEDNAMLMHDRSMFIEKEILCFGEEETFDMADWKLVSNNLNPFKSDYK-------VDVTGLEDKIFKYLNGQNIKVHSLELSDPVSYEDICSNNFGNCQIWGLIFVNNLNFEKKIEIKFTLNNWADIHYINAH-YNKSVTPHVDEFKFIIDISALKLNLISKNLIYTNFFERKTTCLLNLQFCCRYDVNGFEYRSFYDNNDYKNYEITISLSAINLNRAVSNSSIFN-SNLGPSKMGASNAEVTMSKNNENSKK---PLRKFIKDTDYYNDSPLKHKFYQS--------------FETKAACKTEPVSQTFK--------------------AETIDCEIEPFNYFFEPPDSQTNEDMSDSSYDLSLQDFNYWEFSN-------------HGLGKALADSDILQFKN-YPKPEPFSRPPIIDDTFTLNTDDRTLGSKTQKLEDNLAKEWKSAKTRTTLNETPLHDDEHR-------TSFTYTTWNNSTDTLMKRKE-----------ERPVESASCSQLSIATIKAEED-----------------------LLYQDYINSGRESSSPEISPLNTTTSLPFFPGDNMSDSSGEYEERTSLSPNK-------------------------------------IHIFRDYFYKSPSP--------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . : * :: : . . .: . . : .::. :. . . . . . .:: . : * . . * .: .. :. : : .* . . : .. . . *. : . * . . * :.:. . ::: . :. . .: . : * :: .: * ..* .: . . .* *. .. :: :. . : . :. : . : ..* . *: : ..:: : . . : : : .. : . : . .. : :. . .* : : : . : :. . .: . * . . : :* .: . : . : . . . : . : . . . . : . * . *. . . . .: . : * ", "identical_positions": 20, "similar_positions": 163, "identity": "2.36%" }, { "cls_id": "homologset.agr.MGI:1859618", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A0G2JXL5-1", "uniprot_id": "A0A0G2JXL5_RAT", "id": "A0A0G2JXL5-1", "name": "", "aln": "MKLILLYLAVVLCTVCKGTASSSRHKTSGPPSTSEKASHVPEATPTYSEANEVAGEAATWGKGTYKALNGRIFSFESECTFTFCRDCAESGEDFNVEIKRHENGDIEEIKALIDDVGILVVRDTISVNEERVQMPFSNKMIHIKKQGDHYVLKTRRKILSLSWGKNKLSLTLYRQYITCGLCGDFNSVPGEEDINEHIANSKISNDCPSTLSRNNEVCEDGVQYCDRIIGTYFEKCSKVSPLSSEYKNVCVDEYCRTGGNKQTTCNTYSELARLCAYDGPGVFEHWRDDSAVVCAKQQCPGKHIYKECGPSNPPTCSNVAPFQDSECVSGCTCPEGYLLDDIREKGKCVLKEKCPCESNGKVYKPGEVREGPCGSQCTCQEAKWSCTEARCPGICKVEGSSFTTFDDNKFSHPGDCHFLAVHNDEISISVEIHPCGDGQTGSCLTSVMVLLNSSTSGNRFVFNRDGTVTKDGVIIKGYYYSDGVQIFNSSSLYMQAEILSHIKLQIQMVPKMQLYVSLAPDTSTDTVGLCGSFNNKAEDDFMSSQKILESTAQAFANSWEMMPCPKGSPSSCVSIETEKFAESNCEILLSSSGPFAACHQTVDPKFYHEECKRYTCSCENSQDCLCTVLGNYVKACAEKETYLVGWRDGLCEVSCPTGLVFNYKVKTCNSSCRSLSARDRSCDIEDILVDGCTCPDGMYQNNEGNCVQKSECDCYVEDETVQPGKSILIDDNKCVCQDGVLHCQTPLDLTLQNCSRGAEYIDCKDPKAQRRTERTCATRNIPDFEGDLPCKRGCYCPVGMVRNSKGICIHPDDCPCSFGDREYEQGSVTSVGCNECTCIKGSWNCTQNECQSTCHVYGEGHYRTFDGESYSFDGLCQYTFLEDYCGQENGTFRILTESVPCCENGLTCSRKIIVAFQDQNIILQDGKVTAVQTAESEDCERSASSYSIHTVGLYLIVKLLNGIILIWDKYTKVSVILDPSWQNKVCGLCGNNNGDLKDDFTTRHSSVAAGALEFANSWKTSQECSDTVTQSFPCDSNPYCKAWAEKKCEIIRDDTFRDCHSKVDPTTYYNACIEEACSCDMEGKYLGFCTAVAMYAEACNAAGVCVSWRKPNLCPVYCDYYNAPGECSWHYEPCGTVTAKTCKDQVIGQKFSSLLEGCYAKCPENAPYLDENTMKCVQLSECSCFYNDVIPAGGAVVDDCGRTCSCTAGELECSETPTNSTSADKVSLAPTTSVLSTSAVTTGARSSTSESRETTVRAGSSTMEALTAGKAEAGIMATATTVTVSNATSAPVSTSGNPGTTDAPAGTTASAASTPGKADTTTTTTAAPTAASNESSGPASTAESPASTLGSSTSPVPAVSTGAREGTTAVSNRTSAPVPMSEGVGSSGGPNVTTGPVDSTAGGQSTTPAPTGSSAPALPTSGRSGLRGDSTATAPPVSPSEQRMVTEELATTPPNAASTSEKADTTHTTSTSTTTTMAVSNGTSAAVSTSGQPGSSTGPAGTSGSAASTSRIAEKTTTTNQTNSTATPTTPTNTTTNTIAVSNETTPTASISGETGTPAETIGTSEHAGATTGQADTSTRATTTNTISTVTTVTVSNATSGPVSTSGNPGRTDAPAGTTASAASTPGKADTTTTTTAAPTAVSNESSGPASTAESPASTLGFSTSPVPAVSTVLVEITTAVSKGTSAPVTASKGVGSSTGTNGNSGRVLSTAGGQASTPAPTGSSAPALSTSVTGGLRAASNSTAPPVSPSQQPVYTAELILISPNAAPTSEKSESTTTTSTSTTTNIVTVSNATSAPVSTSGNPGGTDSPAGSNASAATKPARADMTTTTTAAPTEVSNESSGPASTAESPASTLGSSTSPVPAVSTVLMDVTTAVSKGTSAPVTASEGVGSSTGPNGTAGPVVSTAGGQASTPAPTGSSAPALSTSGTSGLRAASNSTAPPVSPTQQPVNTAELALTSPNAAPTSEKAETTSMTSSSTSTTTTSTTTTKTVSSGTSAAVSTSGQPGSSTGPASTTGSAASTSGKGDTTTTTNTTTSTTTISVSNETTTVASISGETGTAAEPVGTSERGASTALKADTTTSATTTTTIVAVSNATSAPVSTSGNPGRTDSPAGTTASAATKPARADTTTTTTAAPTAVSNESSGPASTTESPASTLGSSTSPVPAVSTVLMEFTTALSKGTSAPVTTSEGVGSSTGPNGTAGPVVSTPGGQASTPAPTGSSAPALSTSGTSGLRAASNSTAPPVSPSQQPVNTAELALTSPNAAHTSEKAETTSTTSTSTRATTTTKTVSYGSSAAVSTSGQPGSSTRPADTSGSAASTSGNADTTRTTTTTTSTANPTTTTTTTTIVLSNETTPVAPTSVEDGTPAEPVATSPNAAPTSEKADTTTTTSSSASTTTTSITTMAVSNGTSAAVSTSGQPGSSKGPAGTSGSAASTFGNADTTTTTTTTTTTTTTTTISVSNETTTFASISGETGTPAETVGTSERTASTALKADTTTSATTTNNTVAVSNATSAPVLTSGNPGITDSPAGTTASAATKPARADRITTTTAAPTAVSNESSGPASTAESPGSTLVSSTSPLPAVSTGASEGTTALSQGTSAPVTTSEGVGSSKEPNGTAGPVVSTAGGQASTLPPTGSSAPALSTSGTSGLRAASNSTAPPVSPSQQPVNTAELVLTSPNAAPTSEKAETTSTTSTSTSTTTTTKTVSYGSSAAVSTSGQPGSSKGPAGTSGSASSTTGNADTTTTTTTTTSTANPTTTTTTTTIVLSNETTPVASTSVEDGTPAEPVATSPNAAPTSEKADTTTTTSTSTSTTTTSITTMAVSNGTSAAVSTSGQPGSSKGPAGTSGSEVSTSGKRDTTTTTTTTRTSVSNETTTVASISVETGTPAEPIGTSERAGSTALKADTTTSDTTTTTTTIVAVSNATSAPVSTSGNPGRTDSPAGTTASAATKPVRADTAASNESSGPPSTTEGPASTLGSFTSPVPAVSTVLMDVTTAVSKGNSAPVTTSEGVGSSTGPNGTAGPVVSTSEGQASTPAPTGSSAPALSTSGTSGLRAASNSTAPPVSPSQQPVNTAELALTSPNAAPTSEKAETKSTTSTSNSTTTSTTKTVSSGTSAAVSTSGQRGSSTGPAGTSGSATSTSGNADTTTTTTITTSTANPTTTTTTTTIVLSNETTPVASTSVEDGTPAEPLATSPNAAPTSEKADTTTTTSTSNSTTTASITTMAVSNGTSADVSTSGQPGSSKGPAGTSGSAASTFGNADTTTTTTTTTTTTTISVSNETTTVASISGETGTPAETVGTSERAASTALKADTTTRATTTTNTVAVSNATSAPVSSSGNPGRTDSPAGTTASAATKPARADTTTTTTAAPTAVSDESSGPASTVESPASTLGSSTSPVPAVSTVLMEVTTDLSKGTSAPVTTSEGVGSSTGPNGTAGPVVSTPGAQASTPAPTGSSAPALSTSGTSGLRAASNSTAPPVSPSQQPVNTAELVLTSPNAAPTSEKAETTSTTSTSTSTTTTTKTVSYGSSAAVSTSGQPGSSKGPAGTSGSASSTTGNADTTTTTTTTTSTANPTTTTTTTTIVLSNETTPVASTSVEDGTPAEPVATSPNAAPTSEKADTTTTTSTSTSTTTTSITTMAVSNGTSAAVSTSGQPGSSKGPAGTSGSEVSTSGKRDTTTTTTTTRTSVSNETTTVASISVETGTPAEPIGTSERAGSTALKADTTTSDTTTTTTTIVAVSNATSAPVSTSGNPGRTDSPAGTTASAATKPVRADTAASNESSGPPSTTEGPASTLGSFTSPVPAVSTVLMDVTTAVSKGNSAPVTTSEGVGSSTGPNGTAGPVVSTSEGQASTPAPTGSSAPALSTSGTSGLRAASNSTAPPVSPSQQPVNTAELALTSPNAAPTSEKAETKSTTSTSNSTTTSTTKTVSSGTSAAVSTSGQRGSSTGPAGTSGSATSTSGNADTTTTTTITTSTANPTTTTTTTTIVLSNETTPVASTSVEDGTPAEPLATSPNAAPTSEKADTTTTTSTSNSTTTASITTMAVSNGTSADVSTSGQPGSSKGPAGTSGSAASTFGNADTTTTTTTTTTTTTISVSNETTTVASISGETGTPAETVGTSERAASTALKADTTTRATTTTNTVAVSNATSAPVSSSGNPGRTDSPAGTTASAATKPARADTTTTTTAAPTAVSNESSGPASTVESPASTLGSSTSPVPAVSTVLMEVTTDLSKGTSAPVTTSEGVGSSTGPNGTAGPVVSTPGAQASTPAPTGSSAPALSTSGTSGLRAASNSTEPPVSPSQQPVNTAELALPSPNAAPTSEKAETTSTTSTSTSTTTTTTKTVSYGSSAAVSTSGQPGSSTGPAGTSGSAASTSGNADTTTTTTTTTSTANPTTTTTTTRIVISNETTPVASTSVEDGTPAEPLATSPNAAPTSEKADTTTTTSTSTSTTTTSITTMAVSNGTSAAVSTSGQPGSSKGPAGTSGSAASTSGNADTTTTTTTTNTTTTISVSNEITTVASISGGTGTPAESIGTSERAASTALKADTTTSTTTTTTIVAVSNATSAPVSTSGNPGRTDSPAGTTASAATKPIRADTAVSNESSGPASTAESPASTLGSSTSPLPAVSTGASEGTTAVFKGNSAPVTTSEGVGSSKEPNGTAGPVVSTAGGQASTLPPTGSSAPALSTSGTSGLRAASNSTAPPVSPSQQPVNTAELALTSPNAAPTSEKAETTSTTSTSTSTTTTTKTVSYGSSAAVSTSGQPGSSKGPAGTSGSAASTSGNADTTTTTTTTTSTANPTTTTTTTTIVLSNETKPVASTSVKDGTPAEPFATSPNAAPTSEKADTTTTTSTSTSTTTTSITTMAVSNGTSAAVSTSGQPGSSKGPAGTSGSEVSTSGKRDTTTTTTTTRISVSNETTTVASISVETGTPAEPFGTSERAGSTALKADTTTSDTTTTTIVAVSNATSAPVSTSGNPGRRDSPAGTTASAATKPVRADTAASNESSGPPSTTEGPASTLGSFTSPVPAVSTVLMDVTTAVSKGNSAPVTTSEGVGSSTGPNGTAGPVVSTSEGQASTPAPTGSSAPALSTSGTSGLRAASNSTAPPVSPSQQPVNTAELALTSPNAAPTSEKAETTSTTSTSNSTTTSTTKTVSSGTSAAVSTSGQRGSSTGPAGTSGSATSTSGNADTTTTTTVTTSTANPTTTTTTTTIVLSNETTPVASTSVEDGTPAEPLATSPNAAPTSEKADTTTTTSTSTSTTTASITTMAVSNGTSADVSTSGQPGSSKGPAGTSGSAASTFGNADTTTTTTTTTTTTTISVSNETTTVASISGETGTPAESIGTSERAASTALKADTTTSATTTTTIVAVSNATSAPVSTSGNPGRTDSPAGTTASAATKPIRADTAVSNESSGPASTAESPASTLGSSTSPLPAVSTGASEGTTAVFKGNSAPVTTSEGVGRSKEPNGTPGPVVSTSEGQASTPPPTGGSAPALSTSGTSGLRAASNSTAPPVSPSQQPVNTAELALTSPNAAPTSEKAETTSTTSTSTSTSTTTTTTKTVSHGSSAAVSTSGQPGSSTGPAGTSGSAASTSGNADTTTTTTTTTSTANPTTTTTTTRIVISNETTPVASTSVEDGTPAEPLATSPNAAPTSEKADTTTTTSTSTSTTTTSITTMAVSNGTSADVSTSGQPGSSKGPAGTSGSAASTSGNADTTTTTTTTNTTTTISVSNEITTVASISGGTGTPAESIGTSERAASTALKADTTTSATTTTTIVAVSNATSAPVSTSGNPGRTDSPAGTTASAATKPIRADTAVSNESSGPASTAESPASTLGSSTSPLPAVSTGASEGTTAVFKGNSAPVTTSEGVGSSKEPNGTAGPVVSTSEGQASTPPPTGSSAPALSTSGTSGLRAASNSTAPPVSPSQQPVNTAELALTSPNAAPTSEKAETTSTTSTSTSTTTTTTKTVSHGSSAAVSTSGQPGSSTGPAGTSGSAASTSGNADTTTTTTTTTSPPNSTTTTTTTTSVLSNETTPVASTSVEDGTPAEPVATSPNAAPTSEKADTTTTTSTSTSTTTISITTMAVSNGTSADVSTSRQPGSSKGPAGTSGIEVSTSGKGDTTTTTTTTTISVSNETTTVASISGETGSPAEPVGTSERGASTALKADTTTSATTTTTIVAVSNATSAPVSTSGNPGRTDSPAGTTASAATKPARADTTTTTTAAPTAVSNESSGPASTVESPASTLGSSTSPVPAVSTVLMEVTTALSKGTSAPVTTSEGVGSSTGPNGTAGPVVSTPGGQASTPAPTGSSAPALSTSSTSGLRAASNSTAPPVSPSQQPVNTAELALTSPNAAPTSEKADTTTTTSTSTSTTITSITTMAVSNGTSAAVSTSGQPGSSKGPAGTSGSEVSTSGKRDTTTTTNTTTISVSNETTTVASISGETGTPAEPIGTSERAASTALKADTTTSDTTTTTIVAVSNATSAPVSTSGNPGRTDSPAGTTASAATKPIRADTAVSNESSGPASTTESPASTLGSSTSPVPAVSTVLMDVTTAVSKGTSAPVTTSEGVGSSTGPNGTAGPVVSTSGGQASTPAPTGSSTPALSTSGTSGLRAASNSTAPPVSPSQQPVNTAELALTSPNAAPTSEKAETTSTTSTSTTTTTTKTVSSGTSAAVFTSGQPGSSTGPAGTSGSASSTSGNADTTTTTTTTTSTANPTTTTTTTTIVLSNETTPVASTSAEDGTPVVPVATSPNAAPTSEQADTTTPPSTNSSTSTTSNTIAVSNGMSAAVSTSGQSGSSTGQAGTSGSVAFTSGKADSTTTTSITTTTAISYAVSNVTSPFVSTLGENGEVPEPAFTSANELSTTVEADNSPSFTTSTSLAVSNLTSAGFSSSEEPGTSVGPADTSAGSTITSVKADNTTSTTMTTSLAVPIPKSHVASTSGVPFSPSGSSATSTIAVSISRIVYTTTTATTLAALNETSAPASTPASLSPSTVSAESSTPALSTADANGLSAGSNIISASVSTSGYPGTTVTISAGTTGISAKSNVARGRTSSMPEATTSTNNSGSDGNTITAGSTSAPVSVTKESGSSSQEATSSTGVSGTNATGGNTGKVCKVTGLHTFQMFMFQALSHLSSEATTFTDVGEYPGVRTATKSTSVPPGVTTSPSTSQQATAANPTESQDTENKTVCPSTLPPAPACYGPLGEEKSPGDEWISNCHQCTCTEAQAVDCKPKECPSPPTCKAGEKLVKFKSNDSCCEIGYCEPRTCLFNNTDYSVGSSFDDPNNPCLSYTCSTTGLVAVVQDCPKQTWCAEEDRIYESNKCCYKCKRNCRTTPVNVTIKYNDCRKRIEMARCVGDCKRTVKYNYETFQLENSCSCCREEEYEFREIALDCSNGSTIPYRYRHTTTCSCLDQCEHSTAS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q6JHY2-1", "uniprot_id": "SMGC_MOUSE", "id": "Q6JHY2-1", "name": "Submandibular gland protein C", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MKLILLYLAVVLCFVGKARSFRNGAGFYTSLGGQMRVFDFNKKTLDAKSSG------------------------------------GSKDYNLSDGGKSNSRK--------------NLSPATGGSATQQSNLDDSHAPN---------------------------------LGKSETMLSLLGYLG----AFRPVLSGLTSLPRVGG--------------GAHGNIG------------------------------LRAEISRNGVNLS------------------------GDSSARGSLNVN------------PLSGLSTKSGNDATVQGQQAAASGGSKHNVENSSLSTGSATSNKG------ADKPSEHLSN---------------------------------LFLKGLKGIVEPITSAAGGSVSSAVEN--------------LKAQIKKFIEPLTEDHGPT-------------------------------------------------------------------------------------------------STSASVSGDSSTSSRLDGHSSDGLSKVSGDDPTVQG--------------------------------HDVAASDGSKQNVEDSTLSTGSATSNE--GDDKSSDNSSNTFREDLEK-------------------------------------ILEQITSAPGGSVSSAVEN--------------LKAQIKKFIEPLTEDHGPT----------------------STSASVSGDSSTSSRLDGHSSDGLSKVSGDDPTVQGHDVAASDGSKQNVEDSTLSTGSATSNEGDDKSSDNSSNTFREDLEKILEQITSAPGGSVSTVNNP------DEDRLISIIENLAGHIQQSVTEASQSAERPNAQSSNNLSGKLEP------------KYENPTNGSSSASSADKPYEEGMRKLLKFLEEQYGQTGTDASVSGMSSESSRSNVHLSDGFSMESGDDATVQG-----------------------QQAAASGGPKQNVESSNSSTGSATSNGGGDSNEVRGPSSSAVDSTD---------SGDRGNLADKQGPGFNGPEGVGENNGGSFRAGSLDTGSK----------------SDSGSHNLSSGS------------------------------------------------------GSRSNVSTGGEPSDKNEPADP--------GVSGRVTCPTGKTQSGSPSVA-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : :..:. *:. * . ** * .. *: : ...* :::*:. *:.:: : *:::: . .:* **.*..: ..* . :.** ..:*: * **: *. .** :*: * *::** * *** . .. :* .:*:: * ... *:* .. .*.*:.. .: :**: :: :: .:: :: : .**:. *:.*:. *.. .* :* . *:.*:***..*:.. . *:* :. *:: : *. :* **:**::.*::. * *. * *.. *.*... **:. :: :. :* :: :*.*** * .:::..:.*: .. . :.*:***..*:.. . *:* :. *:: .: *. **::: : ::*:. :. ** .:*. . ..:.: *.:.* .*... *:* :* ::**. . .:: .:: .: :: : .. : .....* :: : .. *. *:* : * . * *:.. .*. : :.*. ::::::: .. .: : . : . *:*** *.. * *..:: : :: . * : :::.. . .**:. . :.: ::.::. :.:.:..* :. ...*.*: *.**. * . *:: .. .. .****..: . **.: : : * **: .* :.* ** : ***.*:*...: **.. * :. .* .* .*.:..*:.: ", "identical_positions": 155, "similar_positions": 341, "identity": "2.09%" }, { "cls_id": "homologset.agr.MGI:1859619", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A0G2JUY5-1", "uniprot_id": "A0A0G2JUY5_RAT", "id": "A0A0G2JUY5-1", "name": "", "aln": "MEVKGQLINSPTFNAPAALFGEAAPQVKSDRLRGLLDRQQALQETLRLKLQELRKVCLQEAELTGQLPPECPLEPGERPQLVRRRPPAARAYPPPHSNPAHHSLCPAEELALEALEREVSVQQQIAAAARRLALAPDLNGEQRRRRRQVQVDALRRLHELEEQLRDFRARLGLPVL---QPLPLSSGAPVNAQGVCLGTRLAQLSQEDVVLHSESSSLSESGASHDNEEPHSCFPLTERPSPPKAWDQFRAVSGGSPERRAPWKPPPSDIYGDLKSRRNSVASPTSPTRSLPRSASSFEGRSVPATPVLTR----GSGPRLCKPEG-LHPRQWSGSQDSQMGFPRPDPASDRAS----LFAARTRRSNSSEALLVDRAAAGGAGSPPAPLAPPAAGPPVCKSSEVLYERPQPVPSFSSRTTGPPDPPRAARPSSAAPASRGPPRLPPVCGDFLLDYSLDRGLPRGSGGAGWGDLLPAPEVPG-PLSRRDGLLAMLPGPPPIYAADGSSPLLRSKDPNSR---AIRSKPCG--------------LPPEAVEGLEVHPNPLLWMPPPTRIPPAG-----------------ERGGHKNLALEGLRDWYIRNSG-----------------------------LAVGPQRRP---------MLPHVGPTHTPFLHARCYEVGQSLYGPPSQ-APLPHSRSFTAPPVSGRYGGAFTDG----------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A2AEV7-1", "uniprot_id": "CC120_MOUSE", "id": "A2AEV7-1", "name": "Coiled-coil domain-containing protein 120", "aln": "MEVKGQLISSPTFTAPAALFGEAAPLVKSDRLRGLLDRQRALQEALSVKLQELRKVCLQEAELTGQLPPECPLEPGERPQLVRRRPPAARAYPPPHPNPAHHSLCPAEELALEALEREVSVQQQIAAAARRLALAPDLNGEQRRRRRQVQVDALRRLHELEEQLRDFRARLGLPVL---QPLPLSAGALVNAQGVCLGTRLAQLSQEDVVLHSESSSLSESGASHDNEEPHSCFPLTERPSPPKAWDQFRAVSGGSPERRAPWKPPPSDIYGDLKSRRNSVASPTSPTRSLPRSASSFEGRSVPATPVLTR----GSGPRLCKPEG-LHSRQWSGSQDSQMGFPRPDPASDRAS----LFAARTRRSNSSEALLVDRAAAGGAGSPPAPLAPPAAGPPVCKSSEVLYERPQPVPSFSSRTTGPPDPPRAARPSSAAPASRGAPRLPTVCGDFLLDYPLDRGLPRGSGGAGWGELLPAPEVPG-PLSRRDGLLAMLPGPPPIYAADGSSPLLRSKDPNTR---AIRSKPSG--------------LPPEAVEGLEVHPNPLLWMPPPTRIPPAG-----------------ERGGHKNLALEGLRDWYIRNSG-----------------------------LAVGPQRRP---------MLPHVGPTHTPFLHARCYEVGQSLYGPPSQ-APLPHSRSFTAPPVSGRYGGAFTDG----------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q96HB5-1", "uniprot_id": "CC120_HUMAN", "id": "Q96HB5-1", "name": "Coiled-coil domain-containing protein 120", "aln": "MEVKGQLISSPTFNAPAALFGEAAPQVKSERLRGLLDRQRTLQEALSLKLQELRKVCLQEAELTGQLPPECPLEPGERPQLVRRRPPTARAYPPPHPNQAHHSLCPAEELALEALEREVSVQQQIAAAARRLALAPDLSTEQRRRRRQVQADALRRLHELEEQLRDVRARLGLPVLPLPQPLPLSTGSVITTQGVCLGMRLAQLSQEDVVLHSESSSLSESGASHDNEEPHGCFSLAERPSPPKAWDQLRAVSGGSPERRTPWKPPPSDLYGDLKSRRNSVASPTSPTRSLPRSASSFEGRSVPATPVLTR----GAGPQLCKPEG-LHSRQWSGSQDSQMGFPRADPASDRAS----LFVARTRRSNSSEALLVDRAAGGGAGSPPAPLAPSASGPPVCKSSEVLYERPQPTPAFSSRTAGPPDPPRAARPSSAAPASRGAPRLPPVCGDFLLDYSLDRGLPRSGGGTGWGELPPAAEVPG-PLSRRDGLLTMLPGPPPVYAADSNSPLLRTKDPHTR---ATRTKPCG--------------LPPEAAEGPEVHPNPLLWMPPPTRIPSAG-----------------ERSGHKNLALEGLRDWYIRNSG-----------------------------LAAGPQRRP---------VLPSVGPPHPPFLHARCYEVGQALYGAPSQ-APLPHSRSFTAPPVSGRYGGCFY------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F1QA47-1", "uniprot_id": "F1QA47_DANRE", "id": "F1QA47-1", "name": "", "aln": "MEVKGRVITAMGLGSPDVQGCQDS-KLQAERVSELQERKQSLQSLLNSRLGELRQVCLLEAELTGKLPRDFPLEEGERPPFVQRRSGLP----PYVTSKGDD------------------------------------DAGQRRQMKALFSGALRRSIDSDKNALHSKR------------------------------TVHRGCHTEETVKSESSSMSDS-TSHDNED------SSPSVAPEHRSLSHPRLAPSSPDSRLCRKLSPVEIYYEMRTRRNSASSSVSPSHSLPRSASNVEGRSVPATPLLSRTAPISVHVRPEVSGG-IALKQWCGSPDVPQFVPLASLEGSSSERRSCPYSSRARRSNSS-EALLDRS-SLPEPAPPRNGMPNRAGPYKSSESLTDGKLRQIYQGSPERQLMGFKDQGRMRSSLGGQSS--GTGYNEILMDYIWGKQQKRPVQIPQSQSAGRIWPDFSTPPSGTPPHYNGFSHS-QLHLATAPSSYSPMLLRGQEAEPRRVKVTRTKSCGPFIPLQQHPQDAVLFSAYDPSSASTTSSIPNLLPHHTELSTAASFSRRPAQFSLPTPEDSTRSLHKALALEGLRDWYLRNALGYSTT-AKGHDGLSMRHS-------HTHHLVHQPQSIAADPLYSVHRQIPQSASFHGHPLHARSVELSLYPEPFPS--EGTTQKESGSEPPSPGTLV----------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8M1QR01-1", "uniprot_id": "A0A8M1QR01_DANRE", "id": "A0A8M1QR01-1", "name": "", "aln": "MEVKSHLIT-----SPDVLAVVDS-KQRAERMVELQERRRSLQSLLNTRLAELKRLCLQEAELTGEVPHEYPLESGEKAPHVRRRAGLSRSSSKHNTKNEEE------------------------------------DGSQRKTKKTLFSGALRRHTDAEQHPQHSKR------------------------------TVHRGCHTENTVKSESSSTSDS-TIQDTED------VSDSLSPSR-----LKLVSGSPDNRISRKLSPVEIYYEMKTRRNSVASSASPSHSLPRSVSNLEGRSVPATPLLSRNGITGAHIRSESSSGTAVVKQWSDNPEAPLQVPVQSQEGSSG-----SYEQGHRRSNSS-ETLLDRHGSAAEDGAQR---PGRNGPYKSSEALMDTTLKQPQRSSPERQINGHTELSRVRSTVGGRGSNGGGGYSEILMDYVWGKQQKMQQQRLQNGPKTRPWPEGPNAPP--PPYRNGFPQSQQLILGNGPPAYSPLMLRGKPGDPRRVKVTRTKSCGPFVSSQQHQQESILLSAYTENNGNTGQKEHSHRPPHYPVESSG----------PTTPDDPTRSLHKALALEGLRDWYLRNALGQTATGGKGKDGTQTQRRRTTSSLHNSHPLKHQPQSFQTDTAYS---QMTQSATFHGHPLHGRSIELSLYQESFSSKTQEVTLTDSSNDRPTPGTLILTMVYFIMSSSTGILM", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "****.::*. :* . : :::*: * :*:::**. * :* **:::** ******::* : *** **:. *:**. . .. .. . **: : : .**** : ::: . : : : .: : .::***** *:* : :*.*: : :* : : .**: * * .* ::* ::::****.:*..**::*****.*..*********:*:* . : . * :**... : .* . .. . : ****** *:** . .. * ** ...: * . ..* *.: .. .* : *:: . . . . . * . :*: .. .. :** : ..* . *:*..* :.. .. .. . * : .:. *. ** **********:**: * ** :. .. * **.*. *:. .* . . * . * .* ", "identical_positions": 135, "similar_positions": 161, "identity": "18.62%" }, { "cls_id": "homologset.agr.MGI:1859631", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9EQX6-1", "uniprot_id": "PDGFC_RAT", "id": "Q9EQX6-1", "name": "Platelet-derived growth factor C", "aln": "MLLLGLLLLTSALAGQRTGTRAESNLSSKLQLSSDKEQNGVQDPRHERVVTISGNGSIHSPKFPHTYPRNTVLVWRLVAVDENVRIQLTFDERFGLEDPEDDLCKYDFVEVEEPSDGSVLGRWCGSGTVPGKQTSKGNHIRIRFVSDEYFPSEPGFCIHYSIIMPQVTETTSPSVLPPSALSLDLLNNAVTAFSTVEELIRFLEPDRWQIDLDSLYKPTWPLLGKAFLYGKKSK-AVNLNLLKEEVKLYSCTPRNFSVSIREELKRTDTIFWPGCLLVKRCGGNCACCLHNCNECQCVPRKVTKKYHEVLQLRPKIGVKGLHKSLTDVALEHHEECDCVCRGNTEG", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8CI19-1", "uniprot_id": "PDGFC_MOUSE", "id": "Q8CI19-1", "name": "Platelet-derived growth factor C", "aln": "MLLLGLLLLTSALAGQRTGTRAESNLSSKLQLSSDKEQNGVQDPRHERVVTISGNGSIHSPKFPHTYPRNMVLVWRLVAVDENVRIQLTFDERFGLEDPEDDICKYDFVEVEEPSDGSVLGRWCGSGTVPGKQTSKGNHIRIRFVSDEYFPSEPGFCIHYSIIMPQVTETTSPSVLPPSSLSLDLLNNAVTAFSTLEELIRYLEPDRWQVDLDSLYKPTWQLLGKAFLYGKKSK-VVNLNLLKEEVKLYSCTPRNFSVSIREELKRTDTIFWPGCLLVKRCGGNCACCLHNCNECQCVPRKVTKKYHEVLQLRPKTGVKGLHKSLTDVALEHHEECDCVCRGNAGG", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9NRA1-1", "uniprot_id": "PDGFC_HUMAN", "id": "Q9NRA1-1", "name": "Platelet-derived growth factor C", "aln": "MSLFGLLLLTSALAGQRQGTQAESNLSSKFQFSSNKEQNGVQDPQHERIITVSTNGSIHSPRFPHTYPRNTVLVWRLVAVEENVWIQLTFDERFGLEDPEDDICKYDFVEVEEPSDGTILGRWCGSGTVPGKQISKGNQIRIRFVSDEYFPSEPGFCIHYNIVMPQFTEAVSPSVLPPSALPLDLLNNAITAFSTLEDLIRYLEPERWQLDLEDLYRPTWQLLGKAFVFGRKSR-VVDLNLLTEEVRLYSCTPRNFSVSIREELKRTDTIFWPGCLLVKRCGGNCACCLHNCNECQCVPSKVTKKYHEVLQLRPKTGVRGLHKSLTDVALEHHEECDCVCRGSTGG", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8N7TD29-1", "uniprot_id": "A0A8N7TD29_DANRE", "id": "A0A8N7TD29-1", "name": "Platelet-derived growth factor C", "aln": "MIPLLLLIVISSLHQHES--VAESSHISKIHHASTKEQNGVHESQHEKVLSVTGDGIIQSPNFPNKYPRNTVIVWQLVAVMESSRIQLTFDPRFGLEDAEDGTCKYDYVEVEEPVGGMVLGRWCGSEMVPGPQLSKGNQILVRFVSDEYFPSDPGFSIRYSLLQQRQSEPEAPAVMPVWMQPVEDLTEAVSAFNTMEEVMKYLEPERWQLDMDDLYKPTWQVLGKSFFHQKKSRGAVDLNLLREDVRLYSCTPRNFSVSLREELKRTDAIFWPSCLLVKRCGGNCACCSYNCYDCQCSPTKVAKKYHEVLMLKHRTGGRGLQKTLADVPLEHHEECNCVCKNDSD-", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* : **:: *:* :. ***. **:: :* ******::.:**:::::: :* *:**.**:.**** *:**:**** *. ****** ******.**. ****:****** .* :******* *** * ****:* :**********:***.*:*.:: : :*. :*:*:* .:: *.:*::**.*:*:::::***:***:*::.**:*** :***:*.. :**: .*:**** *:*:************:********:****.************** :** :*** * **:******* *: : * :**:*:*:**.*******:***:..: ", "identical_positions": 199, "similar_positions": 95, "identity": "57.51%" }, { "cls_id": "homologset.agr.MGI:1859635", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O43900-1", "uniprot_id": "PRIC3_HUMAN", "id": "O43900-1", "name": "Prickle planar cell polarity protein 3", "aln": "------------------------------------MFARGSRRRRSGR----------APPEAEDPDRGQPCN----SCREQCPGFLLHGWRKICQ---HCKCPREEHAVHAVPVDLERIMC--------RLISDFQRHSISDDDSGCASEEYAWVPPGLKPEQVYQFFSCLPEDKVPYVNSPGEKYRIKQLLHQLPPHDSEAQYCTALEEEEKKELRAFSQQRKRENLGRGIVRIFPVTITGAICEECGKQIGGGDIAVFASRAGLGACWHPQCFVCTTCQELLVDLIYFYHVGKVYCGRHHAECLRPRCQACDEIIFSPECTEAEGRHWHMDHFCCFECEASLGGQRYVMRQSRPHCCACYEARHAEYCDGCGEHIGLDQGQMAYEGQHWHASDRCFCCSRCGRALLGRPFLPRRGLIFCSRACSLGSEP----TAPGPSRRSWSAGPVTAPLAASTASFSAVKGASETTTKGTSTELAPATG------------------------------PEEP--------------------SRFLRGAPHRHSMPELGLRSVPE-------------PPPES-------------------------------------PGQPNLRPDDSAFGRQSTPRVSFRDPLVSEGGPRRTLSAPPAQRRRPRSPPPRAPSRRRHHHHN---------HHHHHNRHPSRRRHYQCDAGSGSDSESCSSSPSSSSSESSEDDGFFLGERIPLPPHLCRPMPAQDTAMETFN------SPSLSLPRDSRAGMPRQARD-KNCIVA", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q80VL3-1", "uniprot_id": "PRIC3_MOUSE", "id": "Q80VL3-1", "name": "Prickle planar cell polarity protein 3", "aln": "------------------------------------MFARGSRRRRSGR----------APPEAEDPARGQPCN----SCREQCPGFLLHGWRKICQ---HCKCPREEHAVRTVPVDLERIMC--------RLISDFQRHSISDDDSGCASEEYAWVPPGLKPEQVYQFFSCLPEDKVPYVNSPGEKYRIKQLLHQLPPHDSEAQYCTALEEEEKKELRAFSQQRKRENLGRATVRIFPVTITGAICEECGKQIGGGDIAVFASRAGLGACWHPQCFVCTTCQELLVDLIYFYHAGKVYCGRHHAECLRPRCQACDEIIFSPECTEAEGRHWHMGHFCCFECEASLGGQRYVMRQSRPHCCACYEARHAEYCDGCGEHIGLDQGQMAYEGQHWHASDRCFCCSRCSRPLLGRPFLPRRGLIFCSRACSLGSET----TAPGPGRRSWSAGTVTTPLTTSTASFSATEGTSETASKGTCTKAEPAAG------------------------------PEEP--------------------SHFLRGAPHRHSMPELGLRSAPE-------------PPTES-------------------------------------PGHPAPHPDDNAFGRQSTPRVSFRDPLVSEGGPRRTLSAPPAQRRRPRSPPPRTPSCHHHHHHRRRRQRHRRRGSHHHHHHPGRHGHHRCDLGSGSDSGSCSSSPSSPSSESSEDDGFFLGERIPLPPHLCRPRTTQDTSTETFN------SPAQPLVQESHPVMPRQTRD-KNCIVA", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9U1I1-1", "uniprot_id": "ESN_DROME", "id": "Q9U1I1-1", "name": "Protein espinas", "aln": "MQQAPQQQQHPHPPSSSYYTQTESELLQIEAGGTGLTFASHSQRPESAISQVASTAHLDVPSAASSGSGGSAVSGGSGGAPESAGRFVSPLQRRHCQPPSHLPLNSVASPLRTASYKSAAAVAGHGFHHSHHQQLDFQRNSQSDDDSGCALEEYTWVPPGLRPDQVRLYFSQLPDDKVPYVNSPGEKYRVKQLLHQLPPQDNEVRYCHSLSDEERKELRIFSAQRKREALGRGAVRLLSDERP---CKGCEEPLSGGDIVVFAQRLGAQLCWHPGCFVCSVCKELLVDLIYFQRDGNLYCGRHHAETQKPRCSACDEIIFSDECTEAEGRTWHMKHFACQECEHQLGGQRYIMREGKPYCLACFDTMFAEYCDYCGEVIGVDQGQMSHDGQHWHATDQCFSCCTCRCSLLGRPFLPRRGTIYCSIACSKGEPPTPSDTSSGPQLRPTHRASTSSQIAKSPRRGGERERDPGRKAHHGHPKATGSAGDLLERQERQRMEAAGVADLLLGGGVPGMPRPAHPPPIDLTELGISLDNICAGDKSIFGDTQTLTNSMPDMLLSKADDSHSYQSIDKINLNSPSNSDLTQSTQELANELELDNEPVRELPHDGYEQLFANNRNQEHPAEQYDDEQLDNRPMKEVRFHSVQDTMSRSKSYTDNSNARRRRRRRNQSRSSSEMQINQTN--------LRLHNAQTQVGTTPLNLLNNLDNCDVASICSTCSSSSSSDMDDYVYRLPARKHYGGVRVAYVPNDALAYERKKKMAQDSSLAPGAGNASVGGAPAIMHESKNCTIS", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ** *:* .*. .*. *.. *.. . .. *.. *: *: ** * .:::.. . :. : ****:* ******** ***:******:*:** :** **:**************:*********:*.*.:** :*.:**:**** ** ***** ***. **::. . *: * : :.****.***.* * **** ****:.*:********* : *::******** :***.******** ******** *** **.* *** .******:**:.:*:* **::: .***** *** **:*****:::******:*:**.*. * .*********** *:** *** *. . *:.** *. ...:: :: *. . : . :: .: ::* * .* * * . :***:: * .. : .*.:* :* : **. :..:. .* *:. : . .: . . *:*** * .*:.* : :: . *: : : . : ...* * .*: **.**.. :* : * * . : : * : * : . * * :: *** ::", "identical_positions": 257, "similar_positions": 164, "identity": "32.29%" }, { "cls_id": "homologset.agr.MGI:1859637", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9R044-1", "uniprot_id": "NPHN_RAT", "id": "Q9R044-1", "name": "Adhesion molecule nephrin", "aln": "--------------------------MGAKRVTVRGARTSPIHRMSSLTPLLLMGMLTSGLAESPVPTSAPRGFWALSENLTAVEGTTVKLWCGVRAPGSVVQWAKDGLLLGPNPKMPGFPRYSLEGDRAKGEFHLLIEACDLSDDAEYECQVGRSELGPELVSPKVILSILVSPKVLLLTPEAGSTVTWVAGQEYVVTCVSGDAKPAPDITFIQSGRTILDVS-SNVNEGSEEKLCITEAEARVIPQSSDNGQLLVCEGSNPAL--DTPIKASFTMNILFPPGPPVIDWPGLNEGHVRAGENLELPCTARGGNPPATLQWLKNGKPVSTAWGTEHAQAVAHSVLVMTVRPEDHGARLSCQSYNSVSAGTQERSITLQVTFPPSAITILGSVSQSENKNVTLCCLTKSSRPRVLLRWWLGGRQLLPTDETVMDGLHGGHISMSNLTFLVRREDNGLPLTCEAFSDAFSKETFKKSLTLNVKYPAQKLWIEGPPEGQYIRTGTRVRLVCLAIGGNPDPSLIWFKDSRPVSEPRQPQEPRRVQLGSVEKSGSTFSRELVLIIGPPDNRAKFSCKAG------QLSASTQLVVQFPPTNLTILANSSALRPGDALNLTCVSISSNPPVNLSWDKEGERLEDVAAKPQSAPFKGSAASRSVFLRVSSRDHGQRVTCRAHSEALRETVSSFYRFNVLYPPEFLGEQVRAVTVVEQGQVLLPVSVSANPAPEAFNWTFRGYRLSPAGGPRHRILSGG-ALQLWNVTRADDGFYQLHCQNSEGTAEALLKLDVHYAPTIRALRDPTEVNVGGSVDIVCTVDANPILPEMFSWERLGEEEEDLNLDDMEKVSKGSTGRLRIRQAKLSQAGAYQCIVDNGVAPAARGLVRLVVRFAPQVDQPTPLTKVAAAGDSTSSATLHCRARGVPNIDFTWTKNGVPLDLQDP-RYTEHRYHQGVVHSSLLTIANVSAAQDYALFKCTATNALGSDHTNIQLVSISRPDPPLGLKVVSISPHSVGLEWKPGFDGGLPQRFQIRYEALETPGFLHVDVLPTQATTFTLTGLKPSTRYRIWLLASNALGDSGLTDKGIQVSVTTPGPDQAPE--------------------------------------------------------DTDHQLPTELPPGPPRLPLLPVLFAVGGLLLLSNASCVGGLLWRRRLRRLAEEISEKTEAGSE-DRIRNEYEESQWTGDRDTRSSTVSTAEVDP----NYYSMRDFSPQLPPTLEEVLYHQ---GAEGEDMAFPGHLHDEVERAYGPPGAWGPLYDEVRMDPYDLRWPEVQCEDP----------------------------------------------------RGIYDQVAADMDAVEASSLP---------------------------------FELRGHLV-----------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9QZS7-1", "uniprot_id": "NPHN_MOUSE", "id": "Q9QZS7-1", "name": "Nephrin", "aln": "--------------------------MGAKEATVRGPGASPVHRTCHLIPLLLAGMLTTGLAQSPVPTSAPRGFWALSENLTVVEGSTVKLWCGVRAPGSVVQWAKDGLLLGPNPKIPGFPRYSLEGDSAKGEFHLLIEACDLSDDAEYECQVGRSELGPELVSPSVILSILVSPKVLQLTPEAGSTVTWVAGQEYVVTCVSGDAKPAPDIIFIQGGRTVEDVS-SSVNEGSEEKLFFTEAEARVTPQSSDNGQLLVCEGSNPAL--ATPIKASFTMNILFPPGPPVIDWPGLNEGHVRAGENLELPCIARGGNPPATLQWLKNGKPVSIAWGTEHAQAVAHSVLVMTVRPEDHGARLSCQSYNSVSAETQERSITLQVTFPPSAVTILGSTSQSENKNVTLCCLTKSSRPRVLLRWWLGGRQLLPTDETVMDGLHGGHISMSNLTLLVKREDNGLSLTCEAFSDAFSKETFKKSLTLNVKYPAQKLWIEGPPEGQSIRTGTRVRLVCLAIGGNPEPSLTWLKDSRPVNDPRQSQEPRRVQLGSVEKSGSTFSRELVLIIGPPDNLAKFSCKAG------QLSASTQLVVQFPPTNLTILANSSALRPGDALNLTCVSISSNPPVNLSLDKEGERLDDVAAKPQSAPFKGSAASRSVFLRVSSRDHGHRVTCRAHSEALRETVSSFYRLNVLYPPEFLGEQVRAVTVVEQGQALLPVSVSANPAPEAFNWTFRGYRLSPAGGPRHRILSGG-ALQLWNVTRADDGFYQLHCQNSEGTAEALLKLDVHYAPTIRALKDPTEVNVGGSVDIVCTVDANPILPEMFSWERLGEDEEELNLDDMEKMSKGSTGRLRIRQAKLSQAGAYQCIVDNGVAPAARGLVRLVVRFAPQVDHPTPLTKVAAAGDSTSSATLHCRARGVPNIDFTWTKNGVPLDLQDP-RYTEHKYHQGVVHSSLLTIANVSAAQDYALFKCTATNALGSDHTNIQLVSISRPDPPLGLKVVSVSPHSVGLEWKPGFDGGLPQRFQIRYEALESPGFLYMDVLPAQATTFTLTGLKPSTRYRIWLLASNALGDSGLTDKGIQVSITTPGLDQAPE--------------------------------------------------------DTDQPLPTEQPPGPPRLPLLPVLFAVGGLLLLSNASCVGGLLWRRRLRRLAEEISEKTEAGSEEDRIRNEYEESQWTGDRDTRSSTVSTAEVDP----HYYSMRDFSPQLPPTLEEVSYRQAFTGIEDEDMAFPGHLYDEVERVYGPPGVWGPLYDEVQMDPYDLRWPEVKYEDP----------------------------------------------------RGIYDQVAADMDAGEPGSLP---------------------------------FELRGHLV-----------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O60500-1", "uniprot_id": "NPHN_HUMAN", "id": "O60500-1", "name": "Nephrin", "aln": "---------------------------MALGTTLRAS-------------LLLLGLLTEGLAQLAIPASVPRGFWALPENLTVVEGASVELRCGVSTPGSAVQWAKDGLLLGPDPRIPGFPRYRLEGDPARGEFHLHIEACDLSDDAEYECQVGRSEMGPELVSPRVILSILVPPKLLLLTPEAGTMVTWVAGQEYVVNCVSGDAKPAPDITILLSGQTISDIS-ANVNEGSQQKLFTVEATARVTPRSSDNRQLLVCEASSPAL--EAPIKASFTVNVLFPPGPPVIEWPGLDEGHVRAGQSLELPCVARGGNPLATLQWLKNGQPVSTAWGTEHTQAVARSVLVMTVRPEDHGAQLSCEAHNSVSAGTQEHGITLQVTFPPSAIIILGSASQTENKNVTLSCVSKSSRPRVLLRWWLGWRQLLPMEETVMDGLHGGHISMSNLTFLARREDNGLTLTCEAFSEAFTKETFKKSLILNVKYPAQKLWIEGPPEGQKLRAGTRVRLVCLAIGGNPEPSLMWYKDSRTVTESRLPQESRRVHLGSVEKSGSTFSRELVLVTGPSDNQAKFTCKAG------QLSASTQLAVQFPPTNVTILANASALRPGDALNLTCVSVSSNPPVNLSWDKEGERLEGVAAPPRRAPFKGSAAARSVLLQVSSRDHGQRVTCRAHSAELRETVSSFYRLNVLYRPEFLGEQVLVVTAVEQGEALLPVSVSANPAPEAFNWTFRGYRLSPAGGPRHRILSSG-ALHLWNVTRADDGLYQLHCQNSEGTAEARLRLDVHYAPTIRALQDPTEVNVGGSVDIVCTVDANPILPGMFNWERLGEDEEDQSLDDMEKISRGPTGRLRIHHAKLAQAGAYQCIVDNGVAPPARRLLRLVVRFAPQVEHPTPLTKVAAAGDSTSSATLHCRARGVPNIVFTWTKNGVPLDLQDP-RYTEHTYHQGGVHSSLLTIANVSAAQDYALFTCTATNALGSDQTNIQLVSISRPDPPSGLKVVSLTPHSVGLEWKPGFDGGLPQRFCIRYEALGTPGFHYVDVVPPQATTFTLTGLQPSTRYRVWLLASNALGDSGLADKGTQLPITTPGLHQPSG--------------------------------------------------------EPEDQLPTEPPSGPSGLPLLPVLFALGGLLLLSNASCVGGVLWQRRLRRLAEGISEKTEAGSEEDRVRNEYEESQWTGERDTQSSTVSTTEAEP----YYRSLRDFSPQLPPTQEEVSYSRG-FTGEDEDMAFPGHLYDEVERTYPPSGAWGPLYDEVQMGPWDLHWPEDTYQDP----------------------------------------------------RGIYDQVAGDLDTLEPDSLP---------------------------------FELRGHLV-----------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q0E9F2-1", "uniprot_id": "Q0E9F2_DROME", "id": "Q0E9F2-1", "name": "", "aln": "MALQQQHQRHQQHQQHQQQQQQQQQQQHIKWQQHATKRRRCRQHWIKHLQLLRLLAVIVLASAPVPSHAQQQKFRTTPHDLQVLEGAEAMMRCEVANVAGAVQWTKDGFALGFSAVIPGFPRYSVLGDRKQGIYNLRISNASINDDADYQCQVGPARLNSAIRANAKLTVISPPASIEIKGYSHNSKVEVRENQDLQLKCIVANAKPAAQIVWYRGNVEYKPEKREDTVEESTAKRFTTTSSLKLKPGPDDDYTEYTCQARHKALSPDMPMRATVQLSVLYPPGPPYIEGYSAGE-TLRRGQTVELMCRSRGGNPPAQLIWYKNGSQIRMAY--RTSGRLSENIYTFTAEAGDNKARFRCEASNVMSQNPLKAEVELSVLFAPTHVTVMGPTEARVGDIVPLTCTTAPSNPPAEIKWMVGGRQVRNATSKTIVSPEGGWTTTSNITAVVEPNKRSLVVICHGLNMQLTENVVS-THTINVLYPPAPPLISGYMEGQIIPAGSVQKLLCVSSGGNPLATLTWYKNDKRIN-------------SVIRAADKSVSAEITILANVSDNQAQYRCEASNSATEIPLFQSTTLSVHFAPETVKIRIEPEELRPGMEATIICDSSSSNPPAKLSWWKDGIPIEGINNTSKPGLWGGTVSTLEFRVNVTQEMNGQVYTCQSANEALQRSAHEAVSLDVLYRPKFVPPPSSTAVGVEGESLQVSLQTRANPTPVTYKWTKDGTTIPQD--GDHRIFADGGSLNFTRLHRDDAGIYSCSASNSQGGATLNITVVVEYGTTIKSVSENIVVNPGEDAMLSCTVEGKPLTEEHVKWERVGYDMTVKTSTTFANG----TSYLHIKDAKREDVGNFRCVADNRVDNPTNRDILLIVKFAPEIAKTPTLLRAASG--TGERGRLPCRAQGSPKPQFIWRQDKKDLPINRTYKYEVEERKIDSLTYESTLIVDKVAPADYGAYECVARNELGEAVETVRLEITSQPDPPLSLNILNVTHDTVTLAWTPGFDGGLKASYRVRYRMADREQYKYIDGLP-NSHKLTIGGLRMNTLYLFSVMSWNELGQSSYLPDLARAETKEAPPPSHPASSLGGGPPTTSQTPLGGTSGMLLVGVGAGIVVVLLNVFVIGCCLHKRNEKRLKRGLELMPAELTEDSSNTPNLVIIGISLAAFGFLLVN-ASLVAWFFVHQRRKKVAETTNQPAKTATIEMYAPSSYNDTVTGETLSSVSEKSESYSNEGSSQPEYIDEVRKKAASTYLVEGSDMPPPRYQKDGTLPVIYPNNVVNACTLPHPRHNNGSAAIHMTRDDQMLISKGVYIPSPSPAPPPDGSYYNMNSDRYLSYPPMEYPAALDFTAQPMPMAHLQPMTVTSLATNGGPTLIGNGSVAAVAGGSGTLRRGILRGVVGVPQPDVTHHTSTVGGSPMQMLHDLHPVNLSASTLTTSTTLNGSLPTATATLPRQPHGILKDPNRNKQQQQQQQQQQQQQQLQHQQQLLNASLVGVGVPVSAPLGSLQILNLPPASGGLGNNLLMTTNAFDPTTVGLSSFGAVSQAGGIPVAYTDADGHLV", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "A1Z9X4-1", "uniprot_id": "A1Z9X4_DROME", "id": "A1Z9X4-1", "name": "", "aln": "----------------------MQFWITLTFAVHLATT-----------ICHVMAAVTAPTPAAQVAAPPVQKFHLTPHDLQILEGTDTLLRCEVSNRAGKVQWTKDGFALGFSAVIPGFPRYSVLVDAKQNAYNLQIKNATLEDDAEYQCQVGPAAGNPAIRANAKLSIVAAPSSIVIEGYARNARVEVEERQNLTLHCIAENANPAAEIVWFQGEVPVSTAP-IVTVNQTAPKRFTTSSTLHLQPRAEDDYKEFSCEARHKALPPDVPMRAQVQLSVLYPPGAPFFEGYSQGE-TLHRGQEVQIACRSRGGNPPAQLTWYRNGVAISSPQ--RTSGRLSENVYKFTAAAEDNGANLVCEAKNLLATTPLRAELNLTVLYAPKDVYLSGANQAKVGDSVQLSCVTAPSNPQARISWSINGRPLDNSTYKTTSSSDGGWVSSSNISLTIDSQSRTFIAVCHALNTELTQNVVG-SHTVNVLYPPSPPLLTGYNDGDILISGSILKLQCSSAGGNPPPTLQWYKNDKIIN-------------APSKLVDSKITSELSLLVNASDNNAIYKCKVQNAAIDIPLFATKTLGVHFPPETVKISVVPKNLVPGIRAKLICDSSSSNPPAKISWWKDGIPVEGLNLANRPGLWGGSVSTLEMYVNITQDLDGIVYTCQSHNEVLQRSVHETISLDILYPPKFETPQSTTFVGVEGAPFHVELLASGNPMVITYTWTKDGLPISSNSLSGQRLISDGPRLNISRLSRNDAGVYICEALNSQGTALLEIQVAVEYAPTITAVSEGRSFVAGEPAVLACHIQARPLEAAHVRWSRDGYDLATRTISSFENG----TALLQIASVERSDIGNFTCIVDNQRGAPAAQNVLLVVQTAPEIDHSPGFTRYAAR--LGVRAQLICRSLASPQPSFIWRRHGKDLKMQRRNKFKSVERQVDALNFESALLIENTSPDDYGQYECVVRNSLGQASTTLEFSKPSRPDAPLQLRVGNVSDTGVDLNWTPGFDGGMQTYFRLRLKQHGEDKYKYVDAKP-GHQNISLDGLKPGATYYFSVMAANEAGGSKFMPDIKLTLSKGSQPHS---------------------------------------------------------------AEYTE-KDELPNVMIIGITSAAMVLLVLN-AALVAWFVIRRQNKSQSE-----AEPSNDDVYSKDDS-QSVYKLPITALQADVQKKAAASTYLVENVDIIQSTAYPPKYQESSMCTPPYPLCNPDFTRTLPNPKRHSQRNSATGMIEG--MQMRSKDDHMLISNGLYIPSPSPAS--------------------------------------------SLVIKG--SYISSPSPAPPADGS---------------------------------YFNMSDKYMSYPPVTY----------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . . . : * ..:* :**: . : * * .. ***:***: ** .. :****** : * :. ::* *. . :.***:*:**** : .. : : : : ...: .: * *: : *: :*:**.:* . . : : * . : :: * ..*: *:. ** *::* . :.:*:***.* :: . .* :: *: ::: * :***** * * * :** : . . : ::..: :*. . *: *.: *:: * :: . . : * * :.*. : : *. . .. * * * : .*.* . : * :. * : .. . .** : **:: :.. : *..:. ::::.. : :** **. : * :*: : :*: :* * : **** .:* * *:.: :. . . ....: *: :: . .** * : *:. * :. * *:*.* .:.* .. * ** .: * * *****.::* *:* ::.: : . : *:.:: .. :.::. .* **:: . *:.:. . :::** *:* . . ** : : . .** ::.** * :. :*:::.* *:: .: * * *.* . **:* * : : *.*..** :: : . * . : * ::..*: . *.* * : . : : *. *:* .: : * : *:.** .: : *:*: **:: :.. : : *: . * **: . *: * * :. * :: :: : . : . : : :. **. : *.. * **. .:.: *:**.* *.: .:: * * *.******: : :* . : ::* * .::: **: .: * . ::: * * * . . . . ** . : :: : * :*::. *: *. .. ::: : :* ::... .. :: : . .. . .. . * : : . . * . * .* .* :. : ... .:: : ", "identical_positions": 222, "similar_positions": 397, "identity": "14.15%" }, { "cls_id": "homologset.agr.MGI:1859638", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q6PCT5-1", "uniprot_id": "PQBP1_RAT", "id": "Q6PCT5-1", "name": "Polyglutamine-binding protein 1", "aln": "MPLPVALQTRLAKRGILKHLEPEPEEEIIAEDYDDDPVDYEATRIEGLPPSWYKVFDPSCGLPYYWNVETDLVSWLSPHDPNFVVSKSAKKLRNSNADAEDKSERNLEKVDRNHEKSDRSHEKPDRSHEKADRNHEKSDRERERNYDKVDRERDRDRERER--AFDKADREDGKDRRHHRREELAPYPKNKKATSRKDEELDPMDPSSYSDAPRGTWSTGLPKRNEAKTGADTTAAGPLFQQRPYPSPGAVLRANAEASRSKQQD", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q91VJ5-1", "uniprot_id": "PQBP1_MOUSE", "id": "Q91VJ5-1", "name": "Polyglutamine-binding protein 1", "aln": "MPLPVALQTRLAKRGILKHLEPEPEEEIIAEDYDDDPVDYEATRIEGLPPSWYKVFDPSCGLPYYWNVETDLVSWLSPHDPNFVVTKSAKKVRNNNADAEDKSDRNLEKVDRNHEKSDRSHEKPDRSHEKADRNHEKNDRERERNYDKVDRERDRDRERER--AFDKADREEGKDRRHHRREELAPYPKNKKATSRKDEELDPMDPSSYSDAPRGTWSTGLPKRNEAKTGADTTAAGPLFQQRPYPSPGAVLRANAEASRTKQQD", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O60828-1", "uniprot_id": "PQBP1_HUMAN", "id": "O60828-1", "name": "Polyglutamine-binding protein 1", "aln": "MPLPVALQTRLAKRGILKHLEPEPEEEIIAEDYDDDPVDYEATRLEGLPPSWYKVFDPSCGLPYYWNADTDLVSWLSPHDPNSVVTKSAKKLRSSNADAEEKLDRSHDKSDRGHDKSDRSHEKLDRGHDKSDRGHDKSDRDRERGYDKVDRERERDRERDRDRGYDKADREEGKERRHHRREELAPYPKSKKAVSRKDEELDPMDPSSYSDAPRGTWSTGLPKRNEAKTGADTTAAGPLFQQRPYPSPGAVLRANAEASRTKQQD", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "********************************************:**********************.:************* **:*****:*..*****:* :*. :* **.*:******** **.*:*:**.*:*.**:***.********:*****:* .:******:**:**************.***.******************************************************************:****", "identical_positions": 228, "similar_positions": 30, "identity": "86.04%" }, { "cls_id": "homologset.agr.MGI:1859639", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9JIS7-1", "uniprot_id": "CAC1F_MOUSE", "id": "Q9JIS7-1", "name": "Voltage-dependent L-type calcium channel subunit alpha-1F", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSESEVGKD----TTPE--------------------------------------------------PSPANGTGPG----------PEWGLCPGPPTVGTDT--------------SGASGLGTPRR-----RTQHNKHKTVAVASAQRSPRALFCLTLTNPIRRSCISIVEWKPFDILILLTIFAN-----------CVALGVYIPFPEDDSNTANHNLEQVEYVFLVIFTVETVLKIVAYGLVLHPS-------------------------------AYIRNGWNLLDFIIVVVGLFSVLLEQGPGRPGDAP-HTGGKPGGFDVKALRAFRVLRPLRLVSGVPSLHIVVNSIMKALVPLLHIALLVLFVIIIYAIIGLELFLGRMHKTCYFLGSDMEAEEDPSPCASSGSGRSCTLNHTECRGRWPGPNGGITN----------------------FDNFFFAMLTVFQCITMEGWTDVLYWMQDAMGYELPWVYFVSLVIFGSFFVLNLVLGVLSGEFSKEREKAKARGDFQKLREKQQMEEDLRGYLDWITQAEELDLHDPSVDGNLASLAEEGRAGHRPQLSELTNRRRGRLRWFSHSTRSTHSTSSHASLPASDTGSMTDTPGDEDEEEGTMASCTRCLNKIMKTRICRHFRRANRGLRARCRRAVKSNACYWAVLLLVFLNTLTIASEHHGQPLWLTQTQEYANKVLLCLFTVEMLLKLYGLGPS--------VYVASFFNRFDCFVVCGGILETTLVEVGAMQPLGISVLR-CVRLLRIFKVTRHWASLSNLVASLLNSMKSIASLLLLLFLFIIIFSLLGMQLFGGKFNFDQTHTK-RSTFDTFPQALLTVFQILTGEDWNVVMYDGIMAYGGPFFPGMLVCVYFIILFICGNYILLNVFLAIAVDNLASGDAGTAKDKGREKSSEGNPPKENKVLVPGGENEDAKGARSEGAAPG------MEEEEEEEEE-----------EEEEEEEEEENGAGHVELLQEVVPKEKVVPIPEGSAFFCLSQTNPLRKACHTLIHHHIFTSLILVFIILSSVSLAAEDPIRAHSFRN---HILGYFDYAFTSIFTVEILLKMTVFGAFLHRGSFCRSWFNLLDLLVVSVSLISFGIHS-SAISVVKILRVLRVLRPLRAINRAKGLKHVVQCVFVA-IRTIGNIMIVTTLLQFMFACIGVQLFKGKFYSCTDEAKHTLKESKGSFLIYPDGDVSRPLVRERLWVNSDFNFDNVLSAMMALFTVSTFEGWPALLYKAIDANAEDEGPIYNYHVEISVFFIVYIIIIAFFMMNIFVGFVIITFRAQGEQEYQNCELD---KNQRQCVEYALKAQPLRRYIPKNPHQYRVWATVNSRAFEYLMFLLILLNTVALAMQHYEQTAPFNYAMDILNMVFTGLFTIEMVLKIIAFKPKHYFADAWNTFDALIVVGSVVDIAVTEVNN-------------GGHLGESSEDTSRISITFFRLFRVMRLVKLLSKGEGIRTLLWTFIKSFQALPYVALLIAMIFFIYAVIGMQMFGLVALQDGTQINRNNNFQTFPQAVLLLFRCATGEAWQEIMLAS--LPGNRCDPESDFGPGEEFTCGSSFAIVYFISFFMLCAFLIINLFVAVIMDNFDYLTR---DWSILGPHHLDEFKRIWSEYDPGAKGRIKHLDVVALLRRIQPPLGFGKLCPHRVACKRLVAMNVPLNSDGTVTFNATLFALVRTSLKIKTEGNLDQANQELRMVIKKIWKRIKQKLLDEVIPPP-DEEEVTVGKFYATFLIQDYFRKFRRRKEKGLLG--REAPTSTSSALQAGLRSLQDLGPEIRQALTYVTEEEEEEEE--------AVGQEAEEEEAENNPEPYKDSIDSQPQSRWNSRISVSLPVKEKLP------------DSLSTGPSDDDGLAP------NSRQPSVIQAGSQ---------------PHRRSSGVFMFTIP--EEGSIQL--KGTQGQDNQNE----------EQELPDWTPDLDRAGRDSFEPSPFTTSLVQQHVNG-HMSTPTFAAPHACRSEPSFTIQCLQRLGSCEDLPIPGTYHRGRTSGPSRAQG-------------------SWAAP-PQKGRLLYAPLLLVEES-TVGEG-------------------------YLGKLGG----PLRTFTCLQVPGAHPNPSHRKRGSADSLVEAVLISEGLGLFAQDPRFVALAKQEIADACHLTLDEMDSAASDLLAQR-------------TISLYSDEESILSRFDEEDLGDEMACVHAL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "G3V9W8-1", "uniprot_id": "G3V9W8_RAT", "id": "G3V9W8-1", "name": "Voltage-dependent L-type calcium channel subunit alpha", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSESEVGKD----TTPE--------------------------------------------------PSPANGTGPG----------PEWGLCPGPPTVGTDT--------------SGASGLGTPRR-----RTQHNKHKTVVVASAQRSPRALFCLTLTNPIRRSCISIVEWKPFDILILLTIFAN-----------CVALGVYIPFPEDDSNTANHNLEQVEYVFLVIFTVETVLKIVAYGLVLHPS-------------------------------AYIRNGWNLLDFIIVVVGLFSVLLEQGPGRPGDAP-HTGGKPGGFDVKALRAFRVLRPLRLVSGVPSLHIVLNSIMKALVPLLHIALLVLFVIIIYAIIGLELFLGRMHKTCYFLGSDMEAEEDPSPCASSGSGRSCTLNQTECRGRWPGPNGGITN----------------------FDNFFFAMLTVFQCITMEGWTDVLYWMQDAMGYELPWVYFVSLVIFGSFFVLNLVLGVLSGEFSKEREKAKARGDFQKLREKQQMEEDLRGYLDWITQAEELDLHDPSVDGNLASLAEEGRAGHRPQLSELTNRRRGRLRWFSHSTRSTHSTSSHASLPASDTGSITDTPGDEDEEEGTMASCTLCLNKIMKTKVCRHFRRANRGLRARCRRAVKSNACYWAVLLLVFLNTLTIASEHHGQPVWLTQTQEYANKVLLCLFTVEMLLKLYGLGPS--------VYVASFFNRFDCFVVCGGILETTLVEVGAMQPLGISVLR-CVRLLRIFKVTRHWASLSNLVASLLNSMKSIASLLLLLFLFIIIFSLLGMQLFGGKFNFDQTHTK-RSTFDTFPQALLTVFQILTGEDWNVVMYDGIMAYGGPFFPGMLVCVYFIILFICGNYILLNVFLAIAVDNLASGDAGAAKDKGREKSSEGNPPQENKVLVPGGENEDTEGTKSEGAAPG------MEEEEEEEEE-----------EEEE------NGAGHVELLQEVVPKEKVVPIPEGSAFFCLSQTNPLRKACHTLIHHHVFTSLILVFIILSSVSLAAEDPIRAHSFRN---HILGYFDYAFTSIFTVEILLKMTVFGAFLHQGSFCRSWFNLLDLLVVSVSLISFGIHS-SAISVVKILRVLRVLRPLRAINRAKGLKHVVQCVFVA-IRTIGNIMIVTTLLQFMFACIGVQLFKGKFYSCTDEAKHTLKECKGSFLIYPDGDVSRPLVRERLWVNSDFNFDNVLSAMMALFTVSTFEGWPALLYKAIDAHAEDEGPIYNYHVEISVFFIVYIIIIAFFMMNIFVGFVIITFRAQGEQEYQNCELD---KNQRQCVEYALKAQPLRRYIPKNPHQYRVWATVNSAAFEYLMFLLILLNTVALAMQHYEQTAPFNYAMDILNMVFTGLFTVEMVLKIIAFKPKHYFADAWNTFDALIVVGSVVDIAVTEVNN-------------GGHLGESSEDSSRISITFFRLFRVMRLVKLLSKGEGIRTLLWTFIKSFQALPYVALLIAMIFFIYAVIGMQMFGKVALQDGTQINRNNNFQTFPQAVLLLFRCATGEAWQEIMLAS--LPGNRCDPESDFGPGEEFTCGSNFAIVYFISFFMLCAFLIINLFVAVIMDNFDYLTR---DWSILGPHHLDEFKRIWSEYDPGAKGRIKHLDVVALLRRIQPPLGFGKLCPHRVACKRLVAMNVPLNSDGTVTFNATLFALVRTSLRIKTEGNLDQANQELRMVIKKIWKRIKQKLLDEVIPPP-DEEEVTVGKFYATFLIQDYFRKFRRRKEKGLLG--ADAPTSTSSVLQAGLRSLQDLGPEIRQALTYDTEEEEEEEE--------AAGQEAEEEEAENNPETYKDSIDSQPQAQWNSRISVSLPVKEKLP------------DSLSTGPSDDDGVAP------NSRQPSGLQAGSQ---------------PHRRSSGVFMFTIP--EEGSTQL--KGVQGQDNQNE----------EQEVPDWTPNLDEQAGMPSNPVLLPPHWSQQHVNGHHVPRRRLLPPTPAGRKPSFTIQCLQRQGSCEDLPIPGTYHRGRTSGPGRAQG-------------------SWAAP-PQKGRLLYAPLLLVEES-TVGEG-------------------------YLGKLGG----PLRTFTCLQVPGAPSDPSHRKRGSADSLVEAVLISEGLGLFAQDPRFVALAKQEIADACHLTLDEMDSAASDLLAQR-------------TTSLYSDEESILSRFDEEDLGDEMACVHAL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O60840-1", "uniprot_id": "CAC1F_HUMAN", "id": "O60840-1", "name": "Voltage-dependent L-type calcium channel subunit alpha-1F", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSESEGGKD----TTPE--------------------------------------------------PSPANGAGPG----------PEWGLCPGPPAVEGES--------------SGASGLGTPKR-----RNQHSKHKTVAVASAQRSPRALFCLTLANPLRRSCISIVEWKPFDILILLTIFAN-----------CVALGVYIPFPEDDSNTANHNLEQVEYVFLVIFTVETVLKIVAYGLVLHPS-------------------------------AYIRNGWNLLDFIIVVVGLFSVLLEQGPGRPGDAP-HTGGKPGGFDVKALRAFRVLRPLRLVSGVPSLHIVLNSIMKALVPLLHIALLVLFVIIIYAIIGLELFLGRMHKTCYFLGSDMEAEEDPSPCASSGSGRACTLNQTECRGRWPGPNGGITN----------------------FDNFFFAMLTVFQCVTMEGWTDVLYWMQDAMGYELPWVYFVSLVIFGSFFVLNLVLGVLSGEFSKEREKAKARGDFQKQREKQQMEEDLRGYLDWITQAEELDMEDPSADDNLGSMAEEGRAGHRPQLAELTNRRRGRLRWFSHSTRSTHSTSSHASLPASDTGSMTETQGDEDEEEGALASCTRCLNKIMKTRVCRRLRRANRVLRARCRRAVKSNACYWAVLLLVFLNTLTIASEHHGQPVWLTQIQEYANKVLLCLFTVEMLLKLYGLGPS--------AYVSSFFNRFDCFVVCGGILETTLVEVGAMQPLGISVLR-CVRLLRIFKVTRHWASLSNLVASLLNSMKSIASLLLLLFLFIIIFSLLGMQLFGGKFNFDQTHTK-RSTFDTFPQALLTVFQILTGEDWNVVMYDGIMAYGGPFFPGMLVCIYFIILFICGNYILLNVFLAIAVDNLASGDAGTAKDKGGEKSNEKDLPQENEGLVPGVEKEEEEGARREGADME------EEEEEEEEEE-----------EEEEE-----EGAGGVELLQEVVPKEKVVPIPEGSAFFCLSQTNPLRKGCHTLIHHHVFTNLILVFIILSSVSLAAEDPIRAHSFRN---HILGYFDYAFTSIFTVEILLKMTVFGAFLHRGSFCRSWFNMLDLLVVSVSLISFGIHS-SAISVVKILRVLRVLRPLRAINRAKGLKHVVQCVFVA-IRTIGNIMIVTTLLQFMFACIGVQLFKGKFYTCTDEAKHTPQECKGSFLVYPDGDVSRPLVRERLWVNSDFNFDNVLSAMMALFTVSTFEGWPALLYKAIDAYAEDHGPIYNYRVEISVFFIVYIIIIAFFMMNIFVGFVIITFRAQGEQEYQNCELD---KNQRQCVEYALKAQPLRRYIPKNPHQYRVWATVNSAAFEYLMFLLILLNTVALAMQHYEQTAPFNYAMDILNMVFTGLFTIEMVLKIIAFKPKHYFTDAWNTFDALIVVGSIVDIAVTEVNN-------------GGHLGESSEDSSRISITFFRLFRVMRLVKLLSKGEGIRTLLWTFIKSFQALPYVALLIAMIFFIYAVIGMQMFGKVALQDGTQINRNNNFQTFPQAVLLLFRCATGEAWQEIMLAS--LPGNRCDPESDFGPGEEFTCGSNFAIAYFISFFMLCAFLIINLFVAVIMDNFDYLTR---DWSILGPHHLDEFKRIWSEYDPGAKGRIKHLDVVALLRRIQPPLGFGKLCPHRVACKRLVAMNMPLNSDGTVTFNATLFALVRTSLKIKTEGNLEQANQELRIVIKKIWKRMKQKLLDEVIPPP-DEEEVTVGKFYATFLIQDYFRKFRRRKEKGLLG--NDAAPSTSSALQAGLRSLQDLGPEMRQALTCDTEEEEEE------------GQEGVEEEDEKDLETNKATMVSQPSARRGSGISVSLPVGDRLP------------DSLSFGPSDDDRGTP------TSSQPSVPQAGSN---------------THRRGSGALIFTIP--EEGNSQP--KGTKGQNKQDE----------DEEVPDRLSYLDEQAGTPPCSVLLPPHRAQRYMDGHLVPRRRLLPPTPAGRKPSFTIQCLQRQGSCEDLPIPGTYHRGRNSGPNRAQG-------------------SWATP-PQRGRLLYAPLLLVEEG-AAGEG-------------------------YLGRSSG----PLRTFTCLHVPGTHSDPSHGKRGSADSLVEAVLISEGLGLFARDPRFVALAKQEIADACRLTLDEMDNAASDLLAQG-------------TSSLYSDEESILSRFDEEDLGDEMACVHAL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9PQW6-1", "uniprot_id": "A0A8M9PQW6_DANRE", "id": "A0A8M9PQW6-1", "name": "Voltage-dependent L-type calcium channel subunit alpha", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MYEENRKRNGYSNEEEEGGG----EAEE--------------------------------------------------EEEEGGEGGGGGDEGDKEEKDEWDEEDRPKMNRTETL------------MSTTSSTATQKK-----KSQHVKKQVQGSNQVQRAPRALYCLKLNNPIRRAALHLVEWKPFDIFILLAIFAN-----------CVALGVSKPFPEDDSNATNHDLEQVEYVFLIIFTIETFLKILAYGLVMHPS-------------------------------SYIRNGWNLLDFVIVIVGLFSVVLETVTHKSGETTSHTPGKPGGLDVKALRAFRVLRPLRLVSGVPSLQIVLNSIMKAMVPLLHISLLVLFVIIIYAIIGLELFIGRMHRTCFFIGTDNYADDDPLPCAFAGHGRQCYVNGSECRGKWEGPNGGITN----------------------FDNFFFAMLTVFQCITMEGWTDVLYWMNDAIGFELPWVYFVSLVIFGSFFVLNLVLGVLSGEFSKEREKAKARGDFQKLREKQQMEEDLCGYMDWITQAEDIDEFD-----------EDG--NRRVTLRDLADKKRGKFGWFSHSN------ETHASLPASETASENTENIDEEHTD----CCAACCARIMKIPCCRALRRWNRCIRRNCRTAVKSVTFYWLVLILVFLNTALSASEHYNQPEWLTDVQDIANKVLLSLFTVEMLLKMYSLGLQ--------VYFVAFFNRFDCFVVCGGILETVLVEMEIMPPLGISVLR-CVRLLRIFKVTRHWTALSNLVASLLNSMKSIASLLLLLFLFLIIFALLGMQLFGGKFNFDETQTK-RSTFDSFPQALLTCFQILTGEDWNVVMYDGIMAYGGPVFPGMIVCLYFVILFICGNYILLNVFLAIAVDNLAGGDGDNKKNE-EKKEGEAEP------------AEEENGEVKVDMDEE------YEEEEEPEEG-----------DDEE-------GKIQLNVADFAPPKEKILPIPEGSAFFCLSKTNPIRVGCHTLIHHHIFTNLILVFIILSSISLAAEDPIRAHSFRN---NVLGYADYAFTSIFTVEILLKMTVHGAFLHEGSFCRNWFNLLDLLVVSVSLVSFFLHS-SAISVVKILRVLRVLRPLRAINRAKGLKHVVQCVFVA-IRTIGNIMIVTTLLQFMFACIGVQLFKGKFYRCTDEAKNTPEQCKGTFVVYKDGDVSHPMVRERIWLNSDFNFDNVLMGMMALFTVSTFEGWPALLYKAIDANGENHGPIYNYRVEISIFFIVYIIIIAFFMMNIFVGFVIITFREQGEAEFKNCELD---KNQRQCVEYALKAQPLKLYIPKNPVQYKFWSIINSTGFEYVMFVLILLNTVTLAVQHYDQSKFFSQVMDILNMVFTGLFTVEMIIKLMALRLRHYFVDAWNSFDALIVVGSVVDIVVTEFS--------------------SSEDSSRVSITFFRLFRVMRLVKLLSKGEGIRTLLWTFVKSLQALPYVALLIAMIFFIYAVIGMQTFGKIAMQDHTQINRNNNFQTFPQAVLLLFRCATGEAWQEIMLAS--LPGKRCDAESDFEPGEEFSCGSNIAIVYFISFFMLCAFLIINLFVAVIMDNFDYLTR---DWSILGPHHLDEFKRIWSEYDPEAKGRIKHLDVVALLRRIQPPLGFGKLCPHRVACKRLVAMNMPLNADGTVTFNATLFALVRTALKIKTDGNPDQENEELRIIIKKIWKRTKPKVLDEVIPPP-AEEEVTVGKFYATFLIQDYFRKFRKRKEKVGLEEEGNGNPTALQLCQAGLRTLQELGPEMRLAMNEDLEEEEEG-----------LDEEQEEDDAHYKNENGYAHTEPLSRSRRSSLATTPIGAPVPVPGDGILNGGLGRRSSLAKTPNGNGALENENFRRRDSMRSSIHYQHKNGVIDQLPKRPSYYKYPRRDSRDRFSSPLSRREEGGEYPGEQRFYGKDEDSESVISRERHGYPEDSTIFQGHRDMYDGHSMRHPVYGNHYGNSYGDGRRTARRRLLPATPTGRKASFNIQCLRRQGSSDDLPIPGTYHQNSPPCRARSQGYSSYDSRRSSARSSTGSTASWANTGPRRGRLLYAPLILVEEEGAAGAGGVGIWDKKPGGVGVPASVRHPGSGWYSGPSAGGGGQPYRAYTTLRVPTQLSPHYSEKRGSADSLVEAVLISEGLGLYAKDPKFVAFAKREIADACHMTIDEMESAASDLLNRGGSEKSQKFMNHTDTGLVYSDEEPIRS-HEEEELADEMTCVTSF", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q24270-1", "uniprot_id": "CAC1D_DROME", "id": "Q24270-1", "name": "Voltage-dependent calcium channel type D subunit alpha-1", "aln": "MNTGDRKEQASLTPQQQQSPQQPEQQQPITRHDALDSSSANNKLNHKHNNDKDKDTTSDKNWEAGRDLLPASVVIVDESCASKSQKQPIEPSIVSRSGATSSSQRRRQLQFQRQKEAKLYDRGDGDRDREREREASTSTSTSTSASTTTTNTVMGGGELVNCIAYDDNTLVIERKPSPSSPSTSRRYLKAETPTRGSRKYNRKSSAKSDLEVVVVKPEHHHQHRSPTITLPVPANPLTTSASAGSSPTGAGLAAGLGTASGTVLQQSCSALDPPEDSNQPSGTRRRPTSTELALSNVTSQIVNNATYKLDFKQRRHKSNNGGSESGSLTGIATGPATSPAGPTGPTSSSGKRRKSSCTSCGGGGISAPPPRLTPEEAWQLQPQNSVTSAGSTNSSFSSGGGRDDNSSYSAVGGDSSSSNSCNCDITGDNSTLHGFGVGDVCSFIADCDDNSEDDDGDPNNQDLSSQTLRTAAIVAAVAAAAKEQAQEQSLADCESFSDRRQDADEDVRIIQDCCGGNNDSLEDVGEVDDNADVVVRKNSRNRPSIRRTCRITEEDDDEDENADYGDFDREDQELDDEEPEGTTIDIDEQEQQHDQGDSAEEEDDDE----DVDEYFEEEEDDTQAFSPFYSSSAELIDNFGGGAGKFFNIMDFERGASGEGGFSPNGNGGPGSGDVSRTARYDSGEGDLGGGNNIMGIDSMGIANIPETMNGTTIGPSGAGGQKGGAAAGAAGQKRQQRRGKPQPDRPQRALFCLSVKNPLRALCIRIVEWKPFEFLILLTIFAN-----------CIALAVYTPYPGSDSNVTNQTLEKVEYVFLVIFTAECVMKILAYGFVLHNG-------------------------------AYLRNGWNLLDFTIVVIGAISTALSQLMK-------------DAFDVKALRAFRVLRPLRLVSGVPSLQVVLNSILKAMVPLFHIALLVLFVIIIYAIIGLELFSGKLHKACRDEITG-EYEENIRPCG---VGYQCPPG-YKCYGGWDGPNDGITN----------------------FDNFGLAMLTVFQCVTLEGWTDVLYSIQDAMGSDWQWMYFISMVILGAFFVMNLILGVLSGEFSKERNKAKNRGDFQKLREKQQIEEDLRGYLDWITQAEDIEPDA---------------------VGGLISDGKGKQ---------------PNEMDSTENLGEEMPEVQMTESR--------------WRKMKKDFDRVNRRMRRACRKAVKSQAFYWLIIVLVFLNTGVLATEHYGQLDWLDNFQEYTNVFFIGLFTCEMLLKMYSLGFQ--------GYFVSLFNRFDCFVVIGSITETLLTNTGMMPPLGVSVLR-CVRLLRVFKVTKYWRSLSNLVASLLNSIQSIASLLLLLFLFIVIFALLGMQVFGGKFNFDGKEEKYRMNFDCFWQALLTVFQIMTGEDWNAVMYVGINAYGGVSSYGALACIYFIILFICGNYILLNVFLAIAVDNLADADSLSEVEKEEEPHDESAQKKSHSPTPTIDGMDDHLSIDIDMEQQE------LDDEDKMDHETLSDEEVREMCEEEEEVDEEGMITARPRRMSEVNTATKILPIPPGTSFFLFSQTNRFRVFCHWLCNHSNFGNIILCCIMFSSAMLAAENPLRANDDLN---KVLNKFDYFFTAVFTIELILKLISYGFVLHDGAFCRSAFNLLDLLVVCVSLISLVSSS-NAISVVKILRVLRVLRPLRAINRAKGLKHVVQCVIVA-VKTIGNIVLVTCLLQFMFAVIGVQLFKGKFFKCTDGSKMTQDECYGTYLVYDDGDVHKPRLREREWSNNRFHFDDVAKGMLTLFTVSTFEGWPGLLYVSIDSNKENGGPIHNFRPIVAAYYIIYIIIIAFFMVNIFVGFVIVTFQNEGEQEYKNCDLD---KNQRNCIEFALKAKPVRRYIPKHGIQYKVWWFVTSSSFEYTIFILIMINTVTLAMKFYNQPLWYTELLDALNMIFTAVFALEFVFKLAAFRFKNYFGDAWNVFDFIIVLGSFIDIVYSEIKSKDTSQIAECDIVEGCKSTKKSAGSNLISINFFRLFRVMRLVKLLSKGEGIRTLLWTFIKSFQALPYVALLIVLLFFIYAVVGMQVFGKIALDGGNAITANNNFQTFQQAVLVLFRSATGEAWQEIMMSCSAQPDVKCDMNSDT-PGE--PCGSSIAYPYFISFYVLCSFLIINLFVAVIMDNFDYLTR---DWSILGPHHLDEFIRLWSEYDPDAKGRIKHLDVVTLLRKISPPLGFGKLCPHRMACKRLVSMNMPLNSDGTVLFNATLFAVVRTSLSIKTDGNIDDANSELRATIKQIWKRTNPKLLDQVVPPPGNDDEVTVGKFYATYLIQDYFRRFKKRKEQEGKE---GHPDSNTVTLQAGLRTLHEVSPALKRAISGNLDELDQEPEPMHRRHHTLFGSVWSSIRRHGNGTFRRSAKATASQSNGALAIGGSASAALGVGG-----------SSLVLGSSDPAGGDYLYDTLNRSVADGVNNITRN------------IMQARLAAAGKLQDELQGAGSGGELR----TFGESISMRPLAKNGGGAATVAGTLPPEANAINYDNRNRGILLHPYNNVYAPNGALPGHERMIQSTPASPYDQRRLPTSSDMNGLAESLIGGVLAAEGLGKYCDSEFVG-----------TAAREMREALDMTPEEMNLAAHQILSNEHSLSLIGS-------------------SNGSIFGGSAGGLGGAGSGGVGGLGGSSSIRNAFGGSGSGPSSLSPQHQPYSGTLNSPPIPDNRLRRVATVTTTNNNNKSQVSQNNSNSLNVRAN-----------ANSQMNMSPTGQPVQQQSPLRGQGNQTYSS", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P50077-1", "uniprot_id": "CCH1_YEAST", "id": "P50077-1", "name": "Calcium-channel protein CCH1", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MQGRKRTLTEPFEPNTNPFGDNAAVMTENVEDNSETDGNRLESKPQALVPPALNIVPPESSIHSTEEKKG--DEYNGNDKDSSLISNIFRTRVGRSSHENLSRPKLSLKTASFGAAESSRRNVSPSTKSAKSSSQYIDLNDERLRRRSFSSYSRSSSRR------------VSNSPSSTDRPPRSAKVLSLIAADDMDDFEDLQKGFKSAIDEEGLTWLPQLKSEKSRPVSDVGEDRGEGEQESIPDVHTPNVGASATPGSIHLTPEPAQNGSVSEGLEGSINNSR----------------------------------------------KKPSPKFFHHLSPQKEDKDQTEVIEYAEDILDFETLQRKLESRPFVLYG-------HSLGVFSPTNPLRIKIARFLLHRRYSLLYNTLLTFYAILLAIRTYNPHNVVFLYRFSNWTDYFIFILSACFTGNDIAKIIAFGFWDDSEMFKAYGREYKSILQRSGIMKLYIYLREKYGRKLIDFIIPFRIISPGEETKYQRSSLSTSLTKPYGAKENQRPFGTPRAFARSSWNRIDLVSSVSFWLGMFLSIKSYD------------TKTGIRIFKPLAILRILRLVNVDTGMPSILRGLKYGIPQLVNVSSMLVYFWIFFGILGVQIFQGSFRRQCVWFNPEDPTDTYQYDMQFCGGYLDPVTKRKQNYIYEDGSEGSVSKGFLCPQYSKCVSNANPYNGRISFDNIVNSMELVFVIMSANTFTDLMYYTMDSD-EMAACLFFIVCIFVLTIWLLNLLIAVLVSSFEIANEEYKKKKFIYGSRKTGYVARIVTGYWKYFKLKANQTKFP-----------------------NWSQKGLAIYSHVEFIFVILIICDIGMRASVKVSTSANCNNILLKTDRG-----------ISIVLFIESLARLVLYLPNMWKFLTKPSYVYDFIISIITLVISCLAVEGVLGHMYAWLSIFHISRFYRVIISFNLTKKLWKQILSNGVMIWNLSSFYFFFTFLVAIIMAVYFEGVIPPEEMADQPFGMYSLPNSFLSLFIIGSTENWTDILYALQKHSPNISSTFFCSVFFIIWFLLSNSVILNIFIALISESMEVKEEEKRPQQIKHYLKFVYPQKIQEYTHASLVARIRKKFFGGHRNEDTRDFKQFLMRGTAIMNIAQNMGELADEFKEPPSENLFKKGLSKLTIGVPSLKRLRMFANNPFYKNSDVVFTETNDINGRTYILELNEYEDEK----LDYLKKYPLFNYSYYFFSPQHRFRRFCQRLVPPSTGKRTDGSRFFEDSTDLYNKRSYFHHIERDVFVFIFALATILLIVCSCYVTPLYRMHHKMGTWNWSSALDCAFIGAFSIEFIVKTVADGFIYSPNAYLRNPWNFIDFCVLISMWINLIAYLKNNGNLSRIFKGLTALRALRCLTISNTARQTFNLVMFDGLNKIFEAGLISLSLLFPFTVWGLSIFKGRLGTCNDGSLGRAD----CYNEYSNSVFQWDIMSPRVYQQPYLHLDSFASAFSSLYQIISLEGWVDLLENMMNSSGIGTPATVMGSAGNALFLVLFNFLSMVFILNLFVSFIVNNQARTTGSAYFTIEEKAWLESQKLLSQAKPKAIPNLIELSRVRQFFYQLAVEKKNFYYASFLQVVLYLHIIMLLSRSYNPGNLIGYQGVYFMFSTSVFLIQEALHMCGEGPRLYFRQKWNSIRLSIIIIAFIMNAVAFHVP----------------------ASHYWFHNIKGFFLLVIFLFIIPQNDTLTELLETAMASLPPILSLTYTWGVLFLVYAIALNQIFGLTRLG--SNTTDNINFRTVIKSMIVLFRCSFGEGWNYIMADLT-VSEPYCS--SDDNSTYTDCGSETYAYLLLMSWNIISMYIFVNMFVSLIIGNFSYVYRSGGSRSGINRSEIKKYIEAWSKFDTDGTGELELSYLPRIMHSFDGPLSF-KIWEGRLTIKSLVENYMEVNPDDPYDVKIDLIGLNKELNTIDKAKIIQRKLQYRRFVQSIHYTNAYN----------------GCIRFSDLLLQIPLYTAYSAR---------------ECLGIDQYVHHLYILG----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------KVDKYLENQRNFDVLEMVVTRWKFHCRMKRTIEPEWDVKDPTVSSHISNINVNLEPAPGILEREPIATPRMDYGVNNFMWSPR-------------------------------------------------------------------------------------------------------------------------------------MNQDSTMEPPEEPIDNNDDSANDLIDR--------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * . . . . : : . * . : :*. : ::** : *:. : .: . .. :: *::* . .:.:: :: . :: *..** :*: : :. *. .:: ::.: :** ****. ..: ::..: .: *.::: ::::. *::.*:*:::* * ::: * . : : *.:..::: ***: :* ** :: : :**::* *: ::*: ::. :::::**::.** ..*. .:: * : : *:. : . : ** .::. : . . . . . . : * : : .*. * :: :: * * * : . . ::: :: *:: . . :*. : .::: : . : *:*: * .. * :: *. * : : . .:.* ::::::::: : :::* . :. . : . : : : * : * :. : * . . : :*: : : :. .*:: . .: . . . : :: :. : . . . *: ** * : . .: * :: :: . *: : . * * . *::*:::* * . .:: *. :*::*: *: :.: . .: :*:: * .**.**.:. :: ::..: *:. :..* : ::: * * *: *:.:***:: *.* : . : * :. . : * : : :::*.. .: :*: : ::*** ** ::: . . : : ::: :: .*::*:**.*:: . : . : . :.*: : ** * :.: : .. : :: ::: : : :. :. . *. *.:* :: ::: . : ** : ** : *:: :.: . : : .: :* :: :: ::.:.: : ** * : *: .: :: ::*::**: * ** : . . * **:*. :::::***.: **.*: ** . *. ** . ... * ::*: ::. ::::*:**::*:.**.*: * . * :. .:.:: . **::*. ..*.:: : ::: :. **.* *: *:: * ** : :*.*.. .: *:.: : *.. : . * . :.. :* * : : * : :: * :. . . . . : . * : . . .: .. .: : ", "identical_positions": 186, "similar_positions": 524, "identity": "6.4%" }, { "cls_id": "homologset.agr.MGI:1859644", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q6AYQ0-1", "uniprot_id": "MAGIX_RAT", "id": "Q6AYQ0-1", "name": "PDZ domain-containing protein MAGIX", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MDSHAGNTADPRGSRRGVGLQGSGSPRARQLLERLDARPL-----------------------------AARAAADLSALVRKAGATLRLRHKEAISG---LDSADIEVADSRLPHATLVEHR----------------------------PQHQRSDTQGPRMEPLPVIQNKASYASR--------------------LPQATGRFSVELVRGPAGFGLTLSGGRNVSGNVPLAVCGLLKDGPAQRCGHLQAGDLVLYINGQSTRGLTHAQAVEWIRTGGPRLCLVLQRPQEMNGSRSKEVGGG-----HQKTDRIPDPRGGRMMESRG-TISPVHHRP------KTRTGPGP------SPESVATGHVVRAAEHPAEDLEDR-----IPGSPGPWLVPSEDR--------LSRALGIRGGGVQLAQEMAAGRRRH-----------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q4KL35-1", "uniprot_id": "MAGIX_MOUSE", "id": "Q4KL35-1", "name": "PDZ domain-containing protein MAGIX", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MDSRAGNTADPRGGRRGGGLQGSRSPRARQLLERLDARPL-----------------------------AARAAADLTALVRKAGATLRLRHTEGVSG---LDSADIEVTDSRLPHATLVKHR----------------------------PQHQRSETLGTWTEPLPVTQNKASYALK--------------------VPQATGRFSVELTRGPAGFGLTLSGGRNVSGDAPLTVHGLLKDGPAQRCGRLQAGDLVLYINGQSTQGLTHAQVVERIRTGGPHLCLVLQRPQDMDGSRIKEVGG------HRKTDRSLDPRGSR-VESRS-TISPVHHRP------KTRTSPRP------SPEAVAIGHVVRAVEHPTEDLENR-----IPGTPGPWLVPSEDR--------LSRALGVRGGGAQLALEMAAGRRRH-----------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9H6Y5-1", "uniprot_id": "MAGIX_HUMAN", "id": "Q9H6Y5-1", "name": "PDZ domain-containing protein MAGIX", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MEPRTGDAADPRGSRGGRGPSPLAGPSARQLLARLDARPL-----------------------------AARAAVDVAALVRRAGATLRLRRKEAVSV---LDSADIEVTDSRLPHATIVDHR----------------------------PQHRWLETCN---APPQLIQGKARSAPK--------------------PSQASGHFSVELVRGYAGFGLTLGGGRDVAGDTPLAVRGLLKDGPAQRCGRLEVGDLVLHINGESTQGLTHAQAVERIRAGGPQLHLVIRRPLETHPGKPRGVGEPRKGVVPSWPDRSPDPGGPEVTGSRSSSTSLVQHPPSRTTLKKTRGSPEP------SPEAAADGPTVSPPERRAEDPNDQ-----IPGSPGPWLVPSEER--------LSRALGVRG-AAQLAQEMAAGRRRH-----------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AC58G9L7-1", "uniprot_id": "A0AC58G9L7_DANRE", "id": "A0AC58G9L7-1", "name": "", "aln": "MDKVAVNMSKATVKKLHWRSKVQESFVPLGGGSGELGVAIGGGADYGEFPFVTAAPGGGATVGDIILEIGGTPVLGLTLGDVRGVLNSCPHPIRIKTVSPGSTLCKDLRLYLSKCFTPGSMDSQLQQVIRENLYLRAVPCTTRQPRDGEISGVDYNFVSIEEFFSLEESGALLESGKFKGNYYGTPRPVHIGPDSPPITYQEHRNLLRNFRTRSKSLSNLEKAVEEGDNSEEDSGLSAGSAGASSAPPTTIVSPNQTWDLGGVRDGGLPIENGARGGALPENWELAFSDTGEPYYINHNSKTTSWLDPRTQGKEIVSKTELPAFTDQPSDLKGYSIHTRLLKGPRGFGFNIVGGSRPREFLQVYSVTPGGPSALKTADILVYINDSCVLGLSHKEVVEMLKSVPMGHSVDVVLRRGYPMLYNPDGCPKTSLASPSDTPNTNPAAPGSAQSQVQHPDGQQPAFVNLNRSMSLHNNFYPRMQKEALDANGNTAPQPSYSMANGNGVGGIIGLGAVPLSNGPAPSERMSSSHSDTEVSSVVTRRASLIRSYNNNSLPAPSHTNHSSKSSESDFSSTALPLPQPEVGPTAPPPGAPSIQRPPMPQTSLAVAPPTEHPPCGFNGCPANNPPRPLPGGLGSPGAPGGVGCGGGGELVPVALGRSEGGGMGFSVTAGGQGGQLAVVKRVWDRRQCHSLQPGDAIIKINGADVQSLSFAQVQRVLQEHTKQGEVVLLVYRGGPLCSPGSPNAYKRPPPSLGTPDLTSPSSDGAVPSQSTLSPSSPCGDLPNLVQSTSFLDSVPVTLTLEPRDWLGVEDGPAQWSRTAVSNPGAVSKSHVDTRAAISSRAMDVELRRRPGEGFGFVIASQDVVNGTSSLVSHRFVTVRRGSPAARSGQIQPGDQLEAVEGRSVVTLPHRDLAQILRRAGNTLRLTIVPRSHTNNNLPEYPDFDAESRLRKGHRAKQKDSQFYNVDLERGPTGFGFSLRGGSEYN--MGLYVLGLMEGGPASRSQKIQVSDQLVEINGDSTVGMTHSQAVEQIRKGGARIHLVLKKGNGYVPDYDHEAGAASPSSVFSEEPLVAAVDHTPLRSSRWVDDSGRERRERRGKGRTSRGSGADEGKHGWAEDVSTVGSSRSTRRRKEQQMRSRSLPGTLRGQEGSRREEDEEEEKGDGKQGERKGEGERQRGRQKSKSMGERRQKAKDVRSQRENSLPVNGEKEGGREKRDKNRSSTTEVTQRAPFSFLMPLDNDDDGSGAESAHSFSEVSVSAASIAFLGTQWPPDPFSPSEASGSSTKAPGPWLVPSPHKLSQVLEGKRLSQKNEGLWS", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . :.: * * . . . * * **: *: .::: .* * : . :.**: . . : * *: * * :* * *:: : . : : . : : :.*:* ** :***::* ** : * * **::.***.*. :::..* :: ***:** *:**:*.** ** **.:: **::: . : .* ** * .: .:* . : : : * . .: :: ..: : * *. .*:. :. * * . * : .*. *:: ", "identical_positions": 68, "similar_positions": 95, "identity": "5.16%" }, { "cls_id": "homologset.agr.MGI:1859645", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8CEG8-1", "uniprot_id": "UBP27_MOUSE", "id": "Q8CEG8-1", "name": "Ubiquitin carboxyl-terminal hydrolase 27", "aln": "-------------------------------------------------------------------------------------------------MCKDYVYDIDIEQIAKE-EQGEALKLQASTSTEVSQQQCSVPGLGEKYPTWETTKPELELLGHNPRRRRIASSFTIGLRGLINLGNTCFMNCIVQALTHTPILRDFFLSDRHR--CEMPSPELCLVCEMSSLFRELYSGNPSPHVPYK------------LLHLVWIHARHLAGYRQQDAHEFLIAALDVLHRHCKG-------------DDVGKVASNPN------HCNCIIDQIFTGGLQSDVTCQACHGVS-TTIDPCWDISLDLPGSCTSFWPMSPGRE-SSLNGESHIPGITTLTDCLRRFTRPEHLGSSAKIKCGSCQSYQESTKQLTMKKLPVVACFHFKRFEHSAK-QRRKITTYISFPLELDMTPFMASSKETRVNGQLQLPTNSANNENKYSLFAVVNHQGTLESGHYTSFIRHHRDQWFKCDDAVITKASIKDVLDSEGYLLFYHKQVLEPEPEKVKEMTPQAY", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D3ZGB0-1", "uniprot_id": "D3ZGB0_RAT", "id": "D3ZGB0-1", "name": "Ubiquitin carboxyl-terminal hydrolase", "aln": "-------------------------------------------------------------------------------------------------MCKDYVYDIDIEQIAKE-EQGEALKLQASTSTEFSQQQCSVPSLGEKYPTWETTKPELELLGHNPRRRRIASSFTIGLRGLINLGNTCFMNCIVQALTHTPILRDFFLSDRHR--CEMPSPELCLVCEMSSLFRELYSGNPSPHVPYK------------LLHLVWIHARHLAGYRQQDAHEFLIAALDVLHRHCKG-------------DDVGKVASNPN------HCNCIIDQIFTGGLQSDVTCQACHGVS-TTIDPCWDISLDLPGSCTSFWPMSPGRE-SSLNGESHIPGVTTLTDCLRRFTRPEHLGSSAKIKCGSCQSYQESTKQLTMKKLPVVACFHFKRFEHSAK-QRRKITTYISFPLELDMTPFMASSKETRMNGQLQLPTNSGNNENKYSLFAVVNHQGTLESGHYTSFIRHHRDQWFKCDDAVITKASIKDVLDSEGYLLFYHKQVLEHEPEKVKEMTTQAY", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A6NNY8-1", "uniprot_id": "UBP27_HUMAN", "id": "A6NNY8-1", "name": "Ubiquitin carboxyl-terminal hydrolase 27", "aln": "-------------------------------------------------------------------------------------------------MCKDYVYDKDIEQIAKE-EQGEALKLQASTSTEVSHQQCSVPGLGEKFPTWETTKPELELLGHNPRRRRITSSFTIGLRGLINLGNTCFMNCIVQALTHTPILRDFFLSDRHR--CEMPSPELCLVCEMSSLFRELYSGNPSPHVPYK------------LLHLVWIHARHLAGYRQQDAHEFLIAALDVLHRHCKG-------------DDVGKAANNPN------HCNCIIDQIFTGGLQSDVTCQACHGVS-TTIDPCWDISLDLPGSCTSFWPMSPGRE-SSVNGESHIPGITTLTDCLRRFTRPEHLGSSAKIKCGSCQSYQESTKQLTMNKLPVVACFHFKRFEHSAK-QRRKITTYISFPLELDMTPFMASSKESRMNGQLQLPTNSGNNENKYSLFAVVNHQGTLESGHYTSFIRHHKDQWFKCDDAVITKASIKDVLDSEGYLLFYHKQVLEHESEKVKEMNTQAY", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A6H8I0-1", "uniprot_id": "UBP22_DANRE", "id": "A6H8I0-1", "name": "Ubiquitin carboxyl-terminal hydrolase 22", "aln": "MSPAGCSHVNGFKVDNWKQNLRVIYQCFVWSGSAETRKRKAKSCICHMCGAHLN-RLHSCLHCVFFGCFSKKHIHEHAKNKRHNLAIDLLYGGIYCFVCQDYIYDKDMEQIAKE-EQRKAWKLQG---------------IGEKYSMWEPTKRELELLRHNPKRRKITANCTIGLRGLINLGNTCFMNCIVQALTHTPLLRDFFLSDRHK--CEMQS-NSCLVCEMSQLFQEFYSGHRSPHIPFR------------LLHLVWTHARHLAGYEQQDAHEFLIAALDVLHRHCK--------------DDNGKKANNPN------HCNCIIDQIFTGGLQSDVTCQVCHGVS-TTIDPFWDISLDLPGSSTPFWPLSPGSDGSVVNGDSHPSGATTLTDCLRRFTRPEHLGSSAKIKCSGCHSYQESTKQLTMKRLPIVACFHLKRFEHSAK-LRRKITTYVSFPLELDMTPFMASSKESRMNGQYQQPVDSLNNDNKYSLFAVVNHQGTLESGHYTTFIRQHKDQWFKCDDAIITKASIKDVLDSEGYLLFYHKQFLEYE------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VVR1-1", "uniprot_id": "NOT_DROME", "id": "Q9VVR1-1", "name": "Ubiquitin carboxyl-terminal hydrolase nonstop", "aln": "MSETGCRHYQSYVKEHSYDTFRVIDAYFAACVNRDARERKAIHCNCFECGSYGI-QLYACLHCIYFGCRG-AHITSHLRSKKHNVALELSHGTLYCYACRDFIYDARSREYALINRKLEAKDLQKSIG----------------WVPWVPTTKETNLLLANARRRLVRPNQTIGLRGLLNLGATCFMNCIVQALVHTPLLSDYFMSDRHD--CGSKSSHKCLVCEVSRLFQEFYSGSRSPLSLHR------------LLHLIWNHAKHLAGYEQQDAHEFFIATLDVLHRHCVKAKAEHESKSNSSGSGSGTNSSNSSSSHCYGQCNCIIDQIFTGMLQSDVVCQACNGVS-TTYDPFWDISLDLGETTT--------------HGGVTP---KTLIDCLERYTRAEHLGSAAKIKCSTCKSYQESTKQFSLRTLPSVVSFHLKRFEHSAL-IDRKISSFIQFPVEFDMTPFMSEKK-------------NAYGDFRFSLYAVVNHVGTIDTGHYTAYVRHQKDTWVKCDDHVITMASLKQVLDSEGYLLFYHKNVLEYE------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P50102-1", "uniprot_id": "UBP8_YEAST", "id": "P50102-1", "name": "Ubiquitin carboxyl-terminal hydrolase 8", "aln": "MSICPHIQQVFQNEKSKDGVLKTCNAARYILNHSVPKEKFLNTMKCGTCHEINSGATFMCLQCGFCGCWNHSHFLSHSKQIGHIFGINSNNGLLFCFKCEDYIGNIDLINDAIL------------------------------AKYWDDVCTKTMVPSMERRD---------GLSGLINMGSTCFMSSILQCLIHNPYFIRHSMSQIHSNNCKVRSPDKCFSCALDKIVHELYGALNTKQASSSSTSTNRQTGFIYLLTCAWKINQNLAGYSQQDAHEFWQFIINQIHQSYVLDLP----------NAKEVSRANNK------QCECIVHTVFEGSLESSIVCPGCQNNSKTTIDPFLDLSLDIK-------------------------DKKKLYECLDSFHKKEQLKDFN-YHCGECNSTQDAIKQLGIHKLPSVLVLQLKRFEHLLNGSNRKLDDFIEFPTYLNMKNYCSTKEKDKHS------ENGKVPDIIYELIGIVSHKGTVNEGHYIAFCKISGGQWFKFNDSMVSSISQEEVLKEQAYLLFYTIRQVN--------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *.*:: : : * * . : : : : ** **:*:* ****..*:*.* *.* : . :*: * * * . *: * :. :.:*:*.. : ** * ::**** ******* :: :*: . * . :*:**:. :* * *:*.:.* *:. * ** ** *:***: ..* :** : : *:* . :*. *:* *:: **: :. ** * :::***** **: ::.** ::*. : : .: . : :.* .:*.* **:: *** :: : . *.* :* ::: * ::**..:.***** . :: ", "identical_positions": 104, "similar_positions": 109, "identity": "18.18%" }, { "cls_id": "homologset.agr.MGI:1859646", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0ABK0L400-1", "uniprot_id": "A0ABK0L400_RAT", "id": "A0ABK0L400-1", "name": "", "aln": "MFKKLKQKISEEQQQLQQALAPAQASSSSSTPTRTRSRTSSFTDQLDDATPNRELLAGMVAEPAFLSEYTIFALDPSKQPKTQTGSVNASTQATKSPDG-VNREESSPSQSGDTQTFAQKLQLRVPSMESLFR-SPIKESLFRSS-KESLVRTSSRESLN--QVDLDCAVATFDPPSDMESEAEDAPWSS-----DSLSREQLLQRLRRMERSLSSYRGKYSELVTAFQTLQREKKKLQGILSQSQDKSLRRISELREELQMDQQAKRHLQEEFDACVEEKDQYISVLQTQVSLLKQRLQNGPMSVDVPKPLPPVELQAEAHSDMEKLEEKLEEKLEEKLEEKLEGVGEAVGG-GTSAKTLEMLQQRVKRQENLLQRCKETIGSHKEQCALLLSEKEALQEQLEERLQELEKM----------------------------KGMVITEAKRQMLETLELKDDEIAQLRSHIQRMTTQGEELREQKEKSERAAFEELEKALSTAQKTEDAQRRMKVEMDEQIKAVERAGEEERLRLQHELSRVRQEAVSMAKKNSE-QRADLQKLHAEQLASKEQELSQKLESRERELQEQMRMALEKSRSEYLKLTQEKEQQESLALEELELQKKAILTESENKLQGLRQEAEVHRTRIRELETSLEKSLQESRTQSERLAVHLEAEKSKHKTELTALAEKHRTELEGLQQQQHSLWTERLQNLSQQHQAAVEELREKHQQEKDALLKEKESLFQAHIQDMNEKTLEKLDKKQMELESVSSELSEALKARDQLAEELSVLRGDADQMKQALEAELQEQRRHHQREVDSISGQQEIIVRRTEKALKDEISQLGGLLKEKDEHLQERQAQVHNLEACLQKSAEELQQALAKLDLLQAQQSTTHAQTGAYEEQLAQMQQKVSDLETEKNLLTKQVVEVETQKKRVCVELDAQRAQVQ----QLERQRSELEDKVKSLAQLQESQLKNSHVEKEQAQQILTEKENVILQMREEQAKEIEILKQKLFSKEESISILHEEYETKFKNQEKRMEKIKQKAKEMQEM-KKKLLDQEAKLKKELENTVLELSQKEKQFNAKILEMAQANSAGISDTVSRLEENQRQQIESLTGAHQRELDDLIESWEKKLSQQAEELRDQHEKLIEEKEQELGELKQKVLTVQSEKEEVTQEVARLTEAVTGQDVTLAGLQGQLEQKSAAVLALSDSHAQLQSQVEKLEVDLGCALNEKLSLQEELAELKMLAEREKLRVSELTGKVQAAEEELQSCKS-LHEVSRKSLEDKSLNLRTLLEELASQLD-------RHCERTKALLEAKTNELVCTSRDKADAILARLSRCQRHTATVGEALLRRMGQVSELEAQLTQLTEEQCTLKNSFQQVTNQLEEKENQIKTMKADMEGLIAEKEALQQEGGQQQQVASEKESCITQLKKELSENINAVTLLREELSEKKSEIASLSKQLSDVSAQLENSISPSDKAEAISALSKQHEEQELQLQAQLRELSSKVDALSKEKMSALEQVDHWSNKFSEWKKKAQPRFAQYQSTIKDLQTQLDLKAKEAGEKDEQIRLLKEDLDQQNERFESLKGEME-------KKECDLETELKTRTARVVELEDCITQRKKEVESLNEALRNCSQQRDTEHSGLVQTLQRLEELGQEKDNKVREAEETVLGLRERVSSLEAELRVVRKELDDVNSSVK-SRDGELKALEDKLELESAAK-VELKRKAEQKLAAIRKQLLSQMEAKVQQCAKDTESQLSELRAKLQGREKQIHILEGKLKNLASSPHPERAVVSGSMGNVAASPEQEAADSQECTQKACKERVCVLQRSVIEKERLTQRLQQGEREAAPSQSEV--RHRELSVKLDRARAKQLEDQVLIGCLQEELEER-MKCPSILSQPMGEETGKNNTGLKQNWASMVDTVQKTLQEKELSCQALERRVRELESDLITERDAHRLEVEKLTLKYEKSQSPQQEMGGKNTSVEILEDRPEENSKSHVIESKLGTPMDGRHSDLESKLAGSEREKQKLSKEVGRLQKDLRALRKEHQQELDILRKECEQEAEEKLKQEQEDLELKHSSTLKQLMREFNTQLAQKEQELERTVQETIDKAQEVEAELLQSHQEETQQLHRKIAEKEDDLQRTARRYEEILDAREEEMTAKVMDLQTRLEELQKKYEHRLEQEES-AKDSVTVLELQTQLAQKTTLISDSKLKEQELREQVHNLEDRLKSYEKSVCAAAVGAPYRGGNLYHTEVSLFGEPTEFEYLRKVLFEYMMG-RETKTMAKVITTVLRFPDDQAQKILEREDARLMSWLRTSS--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q91VW5-1", "uniprot_id": "GOGA4_MOUSE", "id": "Q91VW5-1", "name": "Golgin subfamily A member 4", "aln": "MFKKLKQKISEEQQQLQQALAPAQASSSSSTPTRTRSRTSSFTDQLDDVTPNRE---------------------------------NASTQATKSPDG-VSKDESSPSQSGDTQTFAQKLQLRVPSMESLFR-SPIKESLFRSS-KEPLVRTSSRESLN--QLDLDCSAAAFDPPSDMESEAEDAPWNS-----DGLSREQLLQRLRRMERSLSSYRGKYSELVTAFQTLQREKKKLQGILSQSQDKSLRRISELREELQMDQQAKKHLQDEFDACLEEKDQYISVLQTQVSLLKQRLQNGPMNVDAPKPLPPGELQAEVHGDTEK----------------MEGVGEPVGG-GTSAKTLEMLQQRVKRQENLLQRCKETIGSHKEQCALLLSEKEALQEQLDERLQELEKMKELHMAEKTKLITQLRDAKNLIEQLEQDKGMVITETKRQMLETLELKEDEIAQLRSHIKQMTTQGEELREQKEKSERAAFEELEKALSTAQKTEDAQRRMKMEMDEQMKAVERASEEERLRLQHELSRVRQEAASMAKKNSEEQVAALQKLHAEELASKEQELSRRLEARERELQEQMRIALEKSRSEYLKLTQEKEQQESLALEELELQKKAILTESENKLQELGQEAEAYRTRILELETSLEKSLQESKTQSEHLAVHLEAEKNKHNKELTALAEQHRTEVEGLQQQQDSLWTERLQSLSQQHQAAVEELREKYQQEKDALLKEKESLFQAHIQDMNEKTLEKLDKKQMELESVSSELSEALRARDQLAEELSVLRGDADKMKQALEAELEEQRRHHQREVGSISEQQELTVRRAEKALKDELSRLGALLDERDEHLRERQARVQDLEAHLQKSAGELQQALAKLDLLHSEQSAAREQAGAYEEQLAQMQQKVLDLETEKSLLTKQVVEMETHKKHVCEELDAQRAQVQ----QLERQRSELEEKVRSLAQLQDSQLKNSTVEKEQARQSLMEKENIILQMREEQAKEIEILKQTLSSKEESISILHEEYETKFKNQEKRMEKIKQKAKEMQET-KKKLLDQEAKLKKELENTVLELSQKEKQFNAQILEMAQANSAGISDTVSRLEENQRQQIESLTGAHQRKLDDVIEAWEKKLSQQAAELRDKHAEQMEEKEQGLGELRQKVRIVQSEKEELTKEVARLKEAVSGQDVALAGLQGQLEQKSAVIVSLSERESQLQSQVEKLEADLGCSLSEKLSLQEELAELKLLADKSQLRVSELTGQVQAAEKELQSCKS-LHELSKKSLEDKSLNLKSLLEELASQLD-------SRCERTKALLEAKTNELVCTSRDKADAILARLSQCQRHTATVGEALLRRMGQVSELEAQLTQLTEEQRTLKSSFQQVTNQLEEKEKQIKTMKADIEGLLTEKEALQQEGGQQRQAASEKESCITQLKKELAENINAVTLLREELSEKKSEIASLSKQLSDLGAQLESSISPSDKAEAISALSKQHEEQELQLQAQLQELSLKVDALSKEKMSALEQVDHWSNKFSEWKKKAQSRLAQHQSTIKDLQAQLDVKATDAREKEEQICLLKEDLDRQNKKFECLKGEMEVRKSKMEKKECDLETALKTQTARVVELEDCVTQRKKEVESLNETLKNYNQQRDTEHSGLVQRLQHLEELGEEKDNKVREAEETVLRLREHVSSLEAELGTVKKELEHVNSSVK-SRDGELKALEDKLELESAAK-VELKRKAEQKIAAIRKQLLSQMEEKTQRYAKDTENRLSELSAQLKEREKQVHSLEDKLKNLESSPHPEVPAVSRSMQSVAASPEQEAPDSQDCTHKACKERLCMLQRRLSEKEKLLRRLEQGEGEARPSQPEA--QHRALSGKLDCTRARQLEDHVLIGCLPEELEEK-MKCSLIVSQPMGEETG-NNTGVKQNWASVVDSVQKTLQEKELTCQALEQRVKELESDLVRERGAHRLEVEKLTLKYEKSQSSQQEMDGENKCVEVLEDRPEENSQSHEIQSNVGT-VDGLRSDLESKLTGAERDKQKLSKEVARLQKELRALRREHQQELDILKRECEQEAEEKLKQEQEDLELKHTSTLKQLMREFNTQLAQKEQELERTVQETIDKAQEVEAELLESHQEETQQLHRKIAEKEDDLRRTARRYEEILDAREEEMTGKVTDLQTQLEELQKKYQQRLEQEES-TKDSVTILELQTQLAQKTTLISDSKLKEQELREQVHNLEDRLKRYEKNACAATVGTPYKGGNLYHTEVSLFGEPTEFEYLRKVMFEYMMG-RETKTMAKVITTVLKFPDDQAQKILEREDARLMSWLRTSS--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q13439-1", "uniprot_id": "GOGA4_HUMAN", "id": "Q13439-1", "name": "Golgin subfamily A member 4", "aln": "MFKKLKQKISEEQQQLQQALAPAQASSNSSTPTRMRSRTSSFTEQLDEGTPNRE--------------------------------------------------------SGDTQSFAQKLQLRVPSVESLFR-SPIKESLFRSSSKESLVRTSSRESLN--RLDLDSSTASFDPPSDMDSEAEDLVGNS-----DSLNKEQLIQRLRRMERSLSSYRGKYSELVTAYQMLQREKKKLQGILSQSQDKSLRRIAELREELQMDQQAKKHLQEEFDASLEEKDQYISVLQTQVSLLKQRLRNGPMNVDVLKPLPQLEPQAEVFTKEEN----------------PESDGEPVVEDGTSVKTLETLQQRVKRQENLLKRCKETIQSHKEQCTLLTSEKEALQEQLDERLQELEKIKDLHMAEKTKLITQLRDAKNLIEQLEQDKGMVIAETKRQMHETLEMKEEEIAQLRSRIKQMTTQGEELREQKEKSERAAFEELEKALSTAQKTEEARRKLKAEMDEQIKTIEKTSEEERISLQQELSRVKQEVVDVMKKSSEEQIAKLQKLHEKELARKEQELTKKLQTREREFQEQMKVALEKSQSEYLKISQEKEQQESLALEELELQKKAILTESENKLRDLQQEAETYRTRILELESSLEKSLQENKNQSKDLAVHLEAEKNKHNKEITVMVEKHKTELESLKHQQDALWTEKLQVLKQQYQTEMEKLREKCEQEKETLLKDKEIIFQAHIEEMNEKTLEKLDVKQTELESLSSELSEVLKARHKLEEELSVLKDQTDKMKQELEAKMDEQKNHHQQQVDSIIKEHEVSIQRTEKALKDQINQLELLLKERDKHLKEHQAHVENLEADIKRSEGELQQASAKLDVFQSYQSATHEQTKAYEEQLAQLQQKLLDLETERILLTKQVAEVEAQKKDVCTELDAHKIQVQDLMQQLEKQNSEMEQKVKSLTQVYESKLEDGNKEQEQTKQILVEKENMILQMREGQKKEIEILTQKLSAKEDSIHILNEEYETKFKNQEKKMEKVKQKAKEMQETLKKKLLDQEAKLKKELENTALELSQKEKQFNAKMLEMAQANSAGISDAVSRLETNQKEQIESLTEVHRRELNDVISIWEKKLNQQAEELQEIHEIQLQEKEQEVAELKQKILLFGCEKEEMNKEITWLKEEGVKQDTTLNELQEQLKQKSAHVNSLAQDETKLKAHLEKLEVDLNKSLKENTFLQEQLVELKMLAEEDKRKVSELTSKLKTTDEEFQSLKS-SHEKSNKSLEDKSLEFKKLSEELAIQLD-------ICCKKTEALLEAKTNELINISSSKTNAILSRISHCQHRTTKVKEALLIKTCTVSELEAQLRQLTEEQNTLNISFQQATHQLEEKENQIKSMKADIESLVTEKEALQKEGGNQQQAASEKESCITQLKKELSENINAVTLMKEELKEKKVEISSLSKQLTDLNVQLQNSISLSEKEAAISSLRKQYDEEKCELLDQVQDLSFKVDTLSKEKISALEQVDDWSNKFSEWKKKAQSRFTQHQNTVKELQIQLELKSKEAYEKDEQINLLKEELDQQNKRFDCLKGEMEDDKSKMEKKESNLETELKSQTARIMELEDHITQKTIEIESLNEVLKNYNQQKDIEHKELVQKLQHFQELGEEKDNRVKEAEEKILTLENQVYSMKAELETKKKELEHVNLSVK-SKEEELKALEDRLESESAAKLAELKRKAEQKIAAIKKQLLSQMEEKEEQYKKGTESHLSELNTKLQEREREVHILEEKLKSVESS-QSETLIVPRSAKNVAAYTEQEEADSQGCVQKTYEEKISVLQRNLTEKEKLLQRVGQEKEETVSSHFEMRCQYQERLIKLEHAEAKQHEDQSMIGHLQEELEEKNKKYSLIVAQHVEKEGGKNNIQAKQNLENVFDDVQKTLQEKELTCQILEQKIKELDSCLVRQKEVHRVEMEELTSKYEKLQALQQ-MDGRNKPTELLEENTEEKSKSHLVQPKLLSNMEAQHNDLEFKLAGAEREKQKLGKEIVRLQKDLRMLRKEHQQELEILKKEYDQEREEKIKQEQEDLELKHNSTLKQLMREFNTQLAQKEQELEMTIKETINKAQEVEAELLESHQEETNQLLKKIAEKDDDLKRTAKRYEEILDAREEEMTAKVRDLQTQLEELQKKYQQKLEQEENPGNDNVTIMELQTQLAQKTTLISDSKLKEQEFREQIHNLEDRLKKYEKNVYATTVGTPYKGGNLYHTDVSLFGEPTEFEYLRKVLFEYMMG-RETKTMAKVITTVLKFPDDQTQKILEREDARLMFTSPRSGIF", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M2B3Z8-1", "uniprot_id": "A0A8M2B3Z8_DANRE", "id": "A0A8M2B3Z8-1", "name": "", "aln": "MFKKLKQKVIDEQS-PQRSSAQPQVSSGE-----RRPQPPLLHQDAPSSPNDRELLAGMIAEPAFLSEYTIFALDHSKRPKAAQVPSASVKAAGSSPRGSVNGDGVASPQREESQSLAQKLQQKVSSVESLLRGSGRSEGLFRSGSRDSLIRSSSRESLT--QTG-ENEAPAYDPPSDIESEAEDSPGSV-----ESLSREQLLHRLHRVERSLGNYRGKYSELVTAYRTAQRDKEKTQAILSQSQDKALRRIGELREELQMDQQAKKHLQEEFDAALEEKDQMITVLHTQVSLLKKRLQASGGVLSSELQVSPATDTVDANSDVQSPSK-----------DDNSTLNTEGSVDSGSAVDVESLQKRVTRQESLLQRCKEMIRSSKERSAQLSSESEVLQQQLQERLQELEKMKELHTTEKTKLITQLGDAKNLIEQLEQDKGMVIAETKRQMHETLEMKEEEIAQLRSRLQQSITQKDELQEQKEKSEKAAFEELERALGVAQRAEEARRQLQLSMEEQVKQVETASEEERRSLQQELTRVKQEVVTIMKKSSEDRITEMERLHSEAIARKEQEMS-----------AQIKLAVEQCREELLQSAQEREQQASLALEEAELQKAAVQSEGENKAKELQLELESARTRIQELESCLG-----SPEKLDELGTQIEEQRKIHEAEIATLGETHKQELESKVS-------EQITALRQEHDVAMEELIHKHKAEIESILKDKEEQFHSHVEDMNKKILDKLSDKQTELETVSAELSELLNSKQQLEDRLSSVEATSETLRQEFEERIKKEQAKHQAEIEAANK-NEQSFAGVEKMLKEEINHLKIALEEKEKVLEEHVLREK---SLLEDGSAQLEELWLRAQLNKEALEESRSQVSTLTDELQQARDQVKNLEET-----LEAVRNDCKEKEVC----------------LEEKTNELQELVQKIEHIKKDLSEKENLHAATCKTLQEEQNRLRKQLDDQK-----------SSQEKKLENIRKDMDCKLKSQENKLEKFKQKAKEAQDKMKKKLQDQEESAKVELSKKIQELELKDQQLKEKILEMAQTSSEGLSTAMSDLEANHKEHLDKLQVNHKQELEDLVRHWQEKLNQNEEEMQEKHSQTLQDKAQELEEISRLLSSSKEENEQIIKDIQNLREELAMRETTVQKLQTELREAASKLETLSEGEGMLKRQVETMEKNLNQALNERNLLQDELRKVEETSKEKLQAISEELVNTQQKISLLETSKCKEGEHLQRTLAEKTAELQNKEKEFQAQLCSLTMEFKQCCQEAQAKIDGFSVELCKKVDERVGALQLRVIDHQNKVAYLRNIIKTKDNRISTLEKELQHTLDVNHNLKSSLDEITLQFGESSE-------TLKALQTERESLQTDAESRFQVLSEKDLHIKQLCEEKQN-------VSENLKANILQISDLESAINDLKTQLASSIT--EKEEAISLLNQQHSKDKERVTSQMGET---VEKLEKEKTLLQEQVDSLRNKFSELKKK----FSQSHSTVKSLQDKLADMERQIAEKDGQLQTLTASVDNHS----ISKSEMDQALSEKDQRVHALTSELESCSKKVCDLEEQLQLRVKERDQLAADLQQHHNIRESEKTELMKQVQEAQDQSSQNGALMQKTEESLQSLRKDIESAKQELESQRKDFEREKAEILKEKKEAVKAAQVKASSETGVKVAELKKKAEQKIGMIRKQLTSQIEEK-EQVIKDLHVQLETIKQSQIEKEEHIKSLEKTMQETTAKLNEDH---AKHLQELQEKEKDERLTSLQNLQEMYEEKLACLHKDISAK----------EEHSAAAARETSSRLVDLETKLSESNEQIANYQNEVSRLKEDLIEQTSRVQELQQTCSDLREQIKQKQIDEVEREQVCEVQINS--NRLGMEPAMLVAKENMDTVGNQDDWLSQKNLLVKEYEEKLLDLQQRLEDKENELKAQQSSPQRNGESD--GECLINNTNTSENDLQRKLVEAENEKQKIHKDYSRLQKDLRSLRKEHEKELEFLKKEMAEENEKKLKLEMEDMEMKHNSALKQLMREFNTQMALKEKELEGSVKETIEKAQCVETELIESHRDEVSQLQKIISQKEEDLNRTVQRYEQVLQSREVEMGDRVWEVQKELEELQQRSLSGPQ----------GLDELKVHLAEKTTMLSEAKLKEQEYHDRIHALEDKLRRVHKNAVVTHLGSTYK--DMSHNSADPFSEPTEFEYLRKVMFEYMMG-RETKTMAKVITSMLKFPADQAQKVLEREDSRVMPWLR-----", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9W1R3-1", "uniprot_id": "Q9W1R3_DROME", "id": "Q9W1R3-1", "name": "", "aln": "MFANLKNKLIEEVKASPSKFQQFANAAQAAVSSSSSTTPNSETNTSNNEN------------------------------------------------------FFSITEEDTPQNSPYRIQKLPATSASALR-GRSTQSLNGATSRTRKLSNSSMASDVSFRLPTYEAPAVYHLQSDLDETSSEFDDSASTARLDVITKDQLYDAYKKSLDRYHKYRCRYTDLAKKYKELERDSSKARSVLVETQDKALRRISELREQCTLEQQAKAHLEEALRVEMDDMSCKMQAYQTKLQLLGENPENITAALERSGQQLESEQLIDLEESIGK-----------------------SPLSTNGSSGVSDLQRLLKERDEQLKSVTEKYEAVRKQ--------------------------------------------------EEENVLLLAQTKQAIHTELELKDTEVRKLQEKLKQLESQRE--------SHNNEVKEQFKKLQATKQEVDAKLMATEHLLNTLKESYAIKEQQVVTLEAQLEAIRVE----------------------------------------------------------------NEQKVKDLQKQNEDRNTQASDSSEQLKKLQAAVQDAESQLLSKD---------------QLLESLRSEQAAKEQQLKHLKEQLG-------------------KLKQENENYLDKLRENKKS--------------------SDSQTNEAQDQQKKLQAAKDEAESKLLATEELLHSLRNDYKAQEEKVALLEDKLKTLSKENDVNVEKLHHINEQREAQSTDSQ-QKINELRAAKDEAEAKLLSTEHSLNALQAALSAKEEQAASLEQSLNALKTESEHSLQDLRLHNDQLLEIVQRHQ-------------------------------------------QNDWEAQLARAREELAAIQSQRELHALELEKSLEMERE--------------------------SVAALNSEKASQEEQHRLKLEQLQREIQILQDQHANSESETVAALKGQLEALSQDLATSQASLLAKEKELKASGNK---------------------------------------LNKIKKQHEQHQAKSSDQSARLEALQSELADRLSHSRQVESEKEELQARVTGILEEIGTMQAQMQQVQDSHSELEREKRKLESRIESLQQEQVDSSAQDERTSAKLEEIQSENTKLAERNCLLEEQTNHLESQLQ---------------------------------------------------------------------------------------AKQDEIGKIQAKLQQVLDEHSKLQNAQELMDHDHR--------------TLQDKCDAYEKDKLLTKHTLDCLQSASEELHRVKAN-------LDRELKEQDQQLSELRERQREQEQQLK------DQAERCAKLKAQNSESETQLQATISNLREQLDAYKQTEQGIQEKLQATN----------------------------SSYTTQIATLEARWSAANSDVERLHEANDALQLEMEQLKIKHGQEREEVKESIAQKNRQVVELQEAMATRDR---------QLQEKIEASEKLAKFDEILIENEYLNKHTKQLEAELAESAELKEKLKSLQCELYVLQEKAEQHAVQMAEKETQSATATAEVSELKKAIEEQAVELTRQKEHASFVTEQSDAVQKDLLQAQQQLHDKQIELAMSRDEQ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ALLQAEADGLRQEVICLKEHLSPSTDSD----------------------------------------SLRSLNERLQRELEDLKHKSAG-AESNMQQEIEELQANN------------QQMAERINELETLRAG-----------------IQAQQLLASMAPKN--------VQEAAAAGEKAELESKLKEIMNEVQDVTNRNLFLEQKCEN---------FLILEQSNERLKLQNAKLSR--------QLDETLVSMQHSEAVPAN--------------------TEFEYLRNIMFQYLTGNTNNETLVKVISAVLKFSPQQAQVALEKEHQRRSLLNKLI---", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "** :**:*: :* . :: . . : . .*. . ::* .: * :* . .:.* : : : .** * : . :. **::. :.: . : :.::** . :: .** :*::*.. :: :*:..* :.:* ::***:****.****: ::**** **:: : . ::: . : . :*::.** :. . :. : . . . :. **: :..::. *: .* : ::: : ::::::*: : **:*: *: :*:.:::: :* : *.. .:* : * .::: :*: : : :* *:: *: :* :: * ::* *:: : :: : ::..:: : * : .::: . : * :. :: :: :: : * * *: : :::* .: : ... :: . :* :*:: . * .. * : .:* . * : :* .:. .:: :: :* . :::..* .* : * . . : :. : . : : . : : ::* : :: : . : .: .: : : *:: .: :..: : :.:. ::*:.::: : *: :. : * :*. :* .: .: : *: :.. :: : :: * .:: : : : ...:: .: * : :* ::.: * . *: ::*.:: : : : . :* ::: . . : : . :: : :. :: :* : : : .*: : : : * : :: : : :. . : :* . : : .:*. : :::.* . : ** :: : * * .:.: .: : : :: .: : *::: : : : . .::. : **: :. : : . :: :*:: : : : : . *: .. : :: .:: :. *.: : * : ** ::. : .: .. .* . :.. : :: . ::: . : .: . :: . : : . : : . : * . . :. . . .*. .** *... ::**: *::: *.::: * *::: :: *:* : :*** :..** :: *: * ..: *: :: :: ..:::: :: : * . ::: :.::**.. *:: * .:. .. *******:::*:*: * :.:*:.***:::*:*. :*:* **:*. * ", "identical_positions": 167, "similar_positions": 551, "identity": "7.19%" }, { "cls_id": "homologset.agr.MGI:1859648", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZZA1-1", "uniprot_id": "D3ZZA1_RAT", "id": "D3ZZA1-1", "name": "Putative tRNA (cytidine(32)/guanosine(34)-2'-O)-methyltransferase", "aln": "MGRTSKDKRDVYYRLAKEKGWRARSAFKLLQLDEEFQLFKG--VKRAVDLCAAPGSWSQVLSQKVGG-------QSSGQVVAVDLQAMAPLPGVIQIQGDITQLSTAKEIIQHFEG-CPADLVVCDGAPDVTGLHDVDEYMQAQLLLAALNIATHVLKPGGCFVAKIFRGRDVTLLYSQLRIFFSSVLCAKPKSSRNSSIEAFAVCQGYDPPEGFIP--DLTRPLMNHSYETDFNQLHGPAR---------VIVPFVTCGDLSAYDSDRTYS-LDLDNGSEYKYTPPTQPPIAPPYQEACRLKKNGQLAKEFLPQECSIDRVDKLSQPLAI---HTLLAPKVEDNEINCSS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8CBC7-1", "uniprot_id": "TRM7_MOUSE", "id": "Q8CBC7-1", "name": "tRNA (cytidine(32)/guanosine(34)-2'-O)-methyltransferase", "aln": "MGRTSKDKRDVYYRLAKENGWRARSAFKLLQLDEEFQLFKG--VKRAVDLCAAPGSWSQVLSQKVGG-------QGSGQVVAVDLQAMAPLPGVIQIQGDITQLSTAKEIIQHFEG-CPADLVVCDGAPDVTGLHDVDEYMQAQLLLAALNIATHVLKLGGCFVAKIFRGRDVTLLYSQLRIFFSSVLCAKPKSSRNSSIEAFAVCQGYDPPEGFIP--DLTRPLLNHSYDTDFNQLDGPTR---------VIVPFVACGDLSAYDSDRTYS-LDLDGGSEYKYTPPTQPPIAPPYQEACRLKKNGQLAKELLPQECSINSVDKLPQPLAI---HTLLDPKVEDNEIHC--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9UET6-1", "uniprot_id": "TRM7_HUMAN", "id": "Q9UET6-1", "name": "tRNA (cytidine(32)/guanosine(34)-2'-O)-methyltransferase", "aln": "MGRTSKDKRDVYYRLAKENGWRARSAFKLLQLDKEFQLFQG--VTRAVDLCAAPGSWSQVLSQKIGG-------QGSGHVVAVDLQAMAPLPGVVQIQGDITQLSTAKEIIQHFKG-CPADLVVCDGAPDVTGLHDVDEYMQAQLLLAALNIATHVLKPGGCFVAKIFRGRDVTLLYSQLQVFFSSVLCAKPRSSRNSSIEAFAVCQGYDPPEGFIP--DLSKPLLDHSYDPDFNQLDGPTR---------IIVPFVTCGDLSSYDSDRSYP-LDLEGGSEYKYTPPTQPPISPPYQEACTLKRKGQLAKEIRPQDCPISRVDTFPQPLAAPQCHTLLAPEMEDNEMSCSP", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VEP1-1", "uniprot_id": "TRM71_DROME", "id": "Q9VEP1-1", "name": "tRNA (cytidine(32)-2'-O)-methyltransferase", "aln": "MGKTSKDKRDIYYRQAKDEGWRARSAFKLLHVDEAYGILNG--VQRAVDLCAAPGSWSQVLSRKLYDTCETDDEKSAVKIIAVDLQAMAPIRGILQLQGDITKQSTAEAIIGHFGGNEKAQLVVCDGAPDVTGVHEMDEYMQHQLLVAALSIATCVLETGGTFVAKIFKGNATSLLSSQMQIFFKKFDIYKPPSSRPSSIEAFVVCSDFCLPEGYIP--QVINPARDDIR--LLAQKTGSEVN-------RRLVPFIAC---GDLNGLSDP-----EEGKTSSSDE-SKSNLEYVYDAVMDDASYP------------LEFKEILKQVYDE-------QRHII--------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VDD9-1", "uniprot_id": "TRM72_DROME", "id": "Q9VDD9-1", "name": "tRNA (guanosine(34)-2'-O)-methyltransferase", "aln": "MGRTSKDKRDIFYRLAKEQGWRARSAFKLLQADETFQLLEG--LTRAVDLCAAPGSWSQVLAKRLYEPLPPE-EREKVKIIAVDLQGMAPIEGVKQLRADISKESTAEAIIEFFGG-EKAQIVVSDGAPDSTGMHDFDSYVQGELLLSALSISTFILEEGGSFVSKIYRADRTSRLYTQLKRFFKNVCVFKPSASRNSSIEAFVVAREFCLPDGYKP--CNLTTEWHDQPESWVGRKKESPP--------VVQVPFVAYK--GELDSDRTY-----DLGENYVYKEPVQQPLTAAYQDILQKTSQVNIKYEGIR---VIHDEEMLKKWLEN-------DENKSEKLGACVT", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P38238-1", "uniprot_id": "TRM7_YEAST", "id": "P38238-1", "name": "tRNA (cytidine(32)/guanosine(34)-2'-O)-methyltransferase", "aln": "MGKSSKDKRDLYYRKAKEQGYRARSAFKLLQLNDQFHFLDDPNLKRVVDLCAAPGSWSQVLSRKLFDESPSS-DKEDRKIVSVDLQPMSPIPHVTTLQADITHPKTLARILKLFGN-EKADFVCSDGAPDVTGLHDLDEYVQQQLIMSALQLTACILKKGGTFVAKIFRGRDIDMLYSQLGYLFDKIVCAKPRSSRGTSLEAFIVCLGYNPPSNWTPKLDVNTSVDEFFQGCFLNKLCISDKLSHWNEEERNIAEFMACGSLQSFDSDATYHDLPSSVAGTSSSLDPVQSPTNPPYKKALELKRSG-----------------KLTRSV----------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "**::******::** **::*:*********: :. : ::.. : *.**************:::: : ::::**** *:*: : ::.**:: .* *: * . *::* .***** **:*:.*.*:* :*:::**.::: :*: ** **:**::. * :*: :*... ** :** :*:*** *. : *..: * . . . : . . *:: :. . . : *. : : ", "identical_positions": 87, "similar_positions": 89, "identity": "24.79%" }, { "cls_id": "homologset.agr.MGI:1859649", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D4A739-1", "uniprot_id": "D4A739_RAT", "id": "D4A739-1", "name": "Alpha-catulin", "aln": "MATSTAPGG-GGAGAVHSSNASGLAFDSGLEIRTRSVEQTLLPLVSQITTLINHKDNTKKSDKTLQAIQRVGQAVNLAVGRFVKVGEAIANENWDLKEEISIACIEAKQAGETIASLTDVTKWNHLESDGQVTILTDKTGVVQAARLLLSSVTKVLLLADQVVIKQIVTSRNKVLATMERLERVNSFQEFVQIFSQFGNEMVEFAYLTGDRQNDLKDEKKKARMAVARAVLEKGTMMLLTASKTCLRHPSCESAHKNKEGVFDRMRAALEKVIEIVTD-----------CRLNRDTDSSSVSIFTGIKELKLNMEALRENVYFES-----------------------------------------------------KENLSAALEVILERVEDFTDSAYTSHEHRERILELSAQARTEVQQFISVWMQAQSRKTKSAAEELELT----------VLKVSHSLDELRKELHCTAMQLAADLLK-FHADHVVLKALKVTGVEGNLEALAEYACKLSEQKEQLVETCRLLRHVSGTEPLEITCMHAEETFQVTGQQIISAAETLTLHPSSKIAKENLDVFCEAWESQISDLATLLREISDVFEGRRGEKYDHLSLPKPMKNNANLKSVKSDKPDSEEQAKIAKLGLKLGLLSSDADCEIEKWED---DDNEIVRHGRNMSRMAYSLYLFTRGEGPLKTSQDLIHFLEVFATEGLKLTSSIQSFSKQLKD-DDKLMLLLEINKLIPLCHQLQTITKTSLQSK--VFLKVDKCVTKIRSMMTLVVQLLSLCYKLLKK--MGNDRWVS-----------ATNKDAMDGQT------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O88327-1", "uniprot_id": "CTNL1_MOUSE", "id": "O88327-1", "name": "Alpha-catulin", "aln": "MAASPVPGG-GGAGAVHSSNAAGFTFDSGLEIRTRSVEQTLLPLVSQITTLINHKDNTKKSDKTLQAIQRVGQAVNLAVGRFVKVGEAIANENWDLKEEINIACIEAKQAGETIASLTDVTKRSHLESDGQVTILTDKTGVVQAARLLLSSVTKVLLLADRVVIKQIVTSRNKILATMERLEKVNSFQEFVQIFSQFGNEMVEFAHLTGDRQNDLKDEKKKARMAVARAVLEKGTMMLLTASKTCLRHPSCESAHTNKEGVFDRMRVALEKVTEIVTD-----------CRLSGETDSSSVSIFTGIKELKVNIEALRENVCFES-----------------------------------------------------KENLSAALEAVLEHVEDFTDSAYTSHEHRERILELSSQARTELQQLLSVWMQTQSRKTKSAAEELELT----------VLKISHSLDELRRELHCTAMQLAADLLK-FHADHVVLKALKVTGVEGNLEALAEYACKLSEQKEQLVETCRLLRHISGTEPLEITCIHAEETFQVTGQQIISAAETLTLHPSSKIAKENLDVFCEAWESQMSDMATLLREISDVFEGRRGERCDHLSLPKPTKNSANLKSLKPDKPDSEEQAKIAKLGLKLGLLSSDADCEIEKWED---EENEIVRHGRNMSRMAYSLYLFTRGEGPLKTSQDLIHFLEVFAAEGLKLTSSVQSFSKQLKD-DDKLMLLLEINKLIPLCHQLQTITKTSLQSK--VFLKVDKCITKIRSMMTLVVQLLSLCYKLLKK--MENNRWGS-----------ATNKDTMDGQN------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9UBT7-1", "uniprot_id": "CTNL1_HUMAN", "id": "Q9UBT7-1", "name": "Alpha-catulin", "aln": "MAASPGPAGVGGAGAVYGSGSSGFALDSGLEIKTRSVEQTLLPLVSQITTLINHKDNTKKSDKTLQAIQRVGQAVNLAVGRFVKVGEAIANENWDLKEEINIACIEAKQAGETIAALTDITNLNHLESDGQITIFTDKTGVIKAARLLLSSVTKVLLLADRVVIKQIITSRNKVLATMERLEKVNSFQEFVQIFSQFGNEMVEFAHLSGDRQNDLKDEKKKAKMAAARAVLEKCTMMLLTASKTCLRHPNCESAHKNKEGVFDRMKVALDKVIEIVTD-----------CKPNGETDISSISIFTGIKEFKMNIEALRENLYFQS-----------------------------------------------------KENLSVTLEVILERMEDFTDSAYTSHEHRERILELSTQARMELQQLISVWIQAQSKKTKSIAEELELS----------ILKISHSLNELKKELHSTATQLAADLLK-YHADHVVLKALKLTGVEGNLEALAEYACKLSEQKEQLVETCRLLRHISGTEPLEITCIHAEETFQVTGQQIISAAETLTLHPSSKIAKENLDVFCEAWESQISDMSTLLREINDVFEGRRGEKYGYLSLPKPMKNNANLKSLKPDKPDSEEQAKIAKLGLKLGLLTSDADCEIEKWED---QENEIVQYGRNMSSMAYSLYLFTRGEGPLKTSQDLIHQLEVFAAEGLKLTSSVQAFSKQLKD-DDKLMLLLEINKLIPLCHQLQTVTKTSLQNK--VFLKVDKCITKTRSMMALLVQLLSLCYKLLKKLQMENNGWVS-----------VTNKDTMDSKT------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q1LU92-1", "uniprot_id": "Q1LU92_DANRE", "id": "Q1LU92-1", "name": "Alpha-catulin", "aln": "MASSPCGGG---------------NFDCGLEIQTRSVEQTLIPLVSQITTLINHKDKLKKTEKTLRAIQRVGQAVSVAVGRFVAVGEAIAAENEDLKEEMGLACFEARRAGTGIAQLTDVSSLEHCDGDGRSTVFSDRTGMVKAARMLLSSVTKVLVLADCIVIKQIISSRNKVLVTLEQLERVSTFQEFVQIFSQFGNEMVEFAHLTGDRQNDLKDEKKRARMAAARAVLEKCTMMLLTASKTCLRHPDCESARINKEAVFQRMRIALEQVIEIVTD-----------TRSSGEAKALPVSIYAGIKDFKVKVEALRDSLYGVS-----------------------------------------------------CEAVAAQLEALVEKTEDFTDSAYTRHEQRETIIQLCQITRQETKQLINTWRHAQSLKAKEATDEMELS----------ILKTCQCVSDLRQELHKVAVGRATELLK-LHSDHLVLQALKASGGDGNLEAVADYASTLTEHNEQLVETCRLLCHVSGTEPLEITCIHAEETFRVIGPQIISAAQTLALHPTSKIAKENLDVFCEAWESQLCDMAILLKEINDVFEGRRGDKKTYLSLPRPGKHSANLKTVKAAKLDAEEQTTIAKLGLELCLLTSDVDSEVERWDE---QDHEMVRLCQIISSMAYSMYLFTRGEGLLKTTSDLFHQAEVLSDQGLQLCPVLQSLSTQLLD-EDRMLIISETEKLSSACQQLQACAKTPVQGKSAIFQKVDSSIQNTKGILILVVYLLPICNKLIRKCKSERSCLASPQHWREKQLSAPVSEETLNGKGSNGFGVKSLEQHMANLTFLESK--------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A0C4DHD7-1", "uniprot_id": "A0A0C4DHD7_DROME", "id": "A0A0C4DHD7-1", "name": "", "aln": "----------------------------------------MYGITQSTVNNQRFRVRDMDNEQIMSTFGNIGHLLNIAVERFITIGEIIAEENIDIKGDMYEAAKEARDAGKSIERLCDISPLSGMELRHHIEPLKDYGAIILAARSLLSSVTRILLLVDIIVVKKLLTAKKRASESLEKLESVMNFTEFVRAFSVFGTEMIELAYLTGHHRNSFKEERRRAQMFSARQILEKSIAILLTSSKNSLIHSDCVIVKENRDTVFCQIRRAMDLIHFVVKDSIFDTAKHMPFEKQASNPNYENESIYTTIKRIVNLIKRYKYQMSYYEGSGEGNNNSDAYFSFLDDDLWKSEKNLPSAAGGGRMVNNTNFRKHLSSESLDLREELSLAFEKLFEKAHDFTDSPYISHNHRKNILSYCDNCKLEFDLYLNTIMKDQHEGGGGAGGVGGVGGGQVKGRSDPELGMLSSLEELCKQLVVSVSSQIEDFNESLKICSKLVKSFHVLATNYDIDNLNQRSSKFHDCCDHIFDICKLLQHIAPTERLQVQAKCLAINLRIYGPQVFIAAKILWKYSNSSAANENFESFSDMWKWLTNEISMIAKKILVSINTTKGDRD-----ADAEKCESSSDKLTKSGVPATEDGEMVEYSGLEGKNNGDLNTYQSKWSEDLSDDNDILKRAKNMSAMAFLMYQFTKGNGSLRTTQDLFTQAEYFAEEANRLYKVLRHFSYQVPASDNKKDLLNILDRVPTFVQALQFTVKDHTVGKAATFVKVDHVIRETKNLMNVINKVVSKCFECATKYKLNLTGITG-------GLTSERSNENMAGGMCDSKGTTSSSDIPXHYGMARRAKGDARRTRVSFLLF", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : :... .. ..: . ..:: : :: .:*: :.:** **: :** ** ** *:* :: *. **: ** * * *:: . : : :.* .:: *** ******::*:*.* :*:*:::::::: ::*:** * .* ***: ** **.**:*:*:*:*.::*.:*:*:::*:* ** :*** :***:**..* *..* .: *:: ** ::: *:: : :*.* : :.. **:: ** : :: : .: . * :: :* :.*: .*****.* *::*: *:. . : * . :.. : * : * .:.:* ::* . :: : : :::::: . : ::: : : :..: : :::.: *:** *:: ** *:: . .::: * *:: **: * :..*. *:**:: *.: *: ::: : ::* :: :*:: . . * .:. ..:. : *: :.: . ..* : .:*.: ::::::: : :* **: :* **:*:* *:*:.**: * :: :. :* :: :* *: ::: :: ::: . : ** .* .* * *** : : :.:: :: ::. * : * . .:: : . ", "identical_positions": 149, "similar_positions": 274, "identity": "17.29%" }, { "cls_id": "homologset.agr.MGI:1859650", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9WUP0-1", "uniprot_id": "RAMP2_MOUSE", "id": "Q9WUP0-1", "name": "Receptor activity-modifying protein 2", "aln": "MAPLRVERAPGGSRLGVTRAQRPTALCLPP-LLLLLLLLLGAVSASPESLNQSLPESQNQSHPTEDSLVSKG-KMEDYETHVLPCWYEYKSCMDSVK-DWCNWTLISRHYSDLQNCLEYNADKFGLGFPNPLAENIILEAHLIHFANCSLVQPTFSDPPEDVLLAMIIAPICLIPFLVTLVVWRSKDSDAQA", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9JHJ1-1", "uniprot_id": "RAMP2_RAT", "id": "Q9JHJ1-1", "name": "Receptor activity-modifying protein 2", "aln": "MAPLRVERAPGGSQLAVTSAQRPAALRLPPLLLLLLLLLLGAVSTSPESLN--------QSHPTEDSLLSKG-KMEDYETNVLPCWYYYKTSMDSVK-DWCNWTLISRYYSNLRYCLEYEADKFGLGFPNPLAESIILEAHLIHFANCSLVQPTFSDPPEDVLLAMIIAPICLIPFLVTLVVWRSKDGDAQA", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O60895-1", "uniprot_id": "RAMP2_HUMAN", "id": "O60895-1", "name": "Receptor activity-modifying protein 2", "aln": "MASLRVERA-GGPRLPRTRVGRPAAL--------RLLLLLGAVLNPHEALA--------QPLPTTGTPGSEGGTVKNYETAVQFCWNHYKDQMDPIEKDWCDWAMISRPYSTLRDCLEHFAELFDLGFPNPLAERIIFETHQIHFANCSLVQPTFSDPPEDVLLAMIIAPICLIPFLITLVVWRSKDSEAQA", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "**.****** **.:* * . **:** ******** . *:* *. ** .: *:* .:::*** * ** ** **.:: ***:*::*** ** *: ***: *: *.********* **:*:* ***********************************:*********.:***", "identical_positions": 116, "similar_positions": 30, "identity": "60.42%" }, { "cls_id": "homologset.agr.MGI:1859652", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O88441-1", "uniprot_id": "MTX2_MOUSE", "id": "O88441-1", "name": "Metaxin-2", "aln": "---------MSLVAEAFVSQIAATEPWPENATLYQQLR----GEQILLSDN--------------AASLAVQAFLQMCNLPVKVVCRANAEYMSPSG---KVPFIHVGNQVVSELGPIVQFVKAKGHSLSDGLDEVQKAEMKAYMELVNNMLLTAELY---------------------LQWCDEATVGEITIARYGSPYPWPLNHILAYQKQWEVKRKMKAIGWGNKTLDQVLEDVDQCCQALSQRLG------TQPYFFNKQPTELDALVFGHLYTILTTQLTSDEL---SEKVKNYSNLLAFCRRIEQHYFEDWGKGRLS---------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O75431-1", "uniprot_id": "MTX2_HUMAN", "id": "O75431-1", "name": "Metaxin-2", "aln": "---------MSLVAEAFVSQIAAAEPWPENATLYQQLK----GEQILLSDN--------------AASLAVQAFLQMCNLPIKVVCRANAEYMSPSG---KVPFIHVGNQVVSELGPIVQFVKAKGHSLSDGLEEVQKAEMKAYMELVNNMLLTAELY---------------------LQWCDEATVGEITHARYGSPYPWPLNHILAYQKQWEVKRKMKAIGWGKKTLDQVLEDVDQCCQALSQRLG------TQPYFFNKQPTELDALVFGHLYTILTTQLTNDEL---SEKVKNYSNLLAFCRRIEQHYFEDRGKGRLS---------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8I5ZLV1-1", "uniprot_id": "A0A8I5ZLV1_RAT", "id": "A0A8I5ZLV1-1", "name": "Metaxin-2", "aln": "----------MDVAGCFVC--LATEPWPENATLYQQLR----GEQILLSDN--------------AASLAVQTFLQMCNLPVKVVCRANAEYMSPSG---KVPFIHVGNQVVSELGPIIQFVKAKGHSLSDGLDEVQKAEMKAYMELVNNMLLTAELY---------------------LQWCDEATVGEITLARYGSPYPWPLNLILTYQKQCEVKRKMKAIGWGNKTLDQVLEDVDRCCQALSQRLG------TQPYFFDKQPTELDALVFGHLYTILTTQLTSDEL---CEKVKNYSNLLAFCRRIEQDYFEDRGKGRLS---------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9VW58-1", "uniprot_id": "Q9VW58_DROME", "id": "Q9VW58-1", "name": "Metaxin-2", "aln": "-------MTSQYLSQLITADKLSAEPWPEDATLYQPYE----AEQILLPEN--------------ASCLAVKAYLKMCNLPFLIRSCANAEHMSPGGRMTKLPFIRAGAFIFAEFEPIVNFVEQKELAIGSWQDEDEKADMRTYVSLVENIFTMAELY---------------------ISFKNERVYKEVTAPRNGVVFPWPLNHMQNYGKRRNALRLLKVYQWDDLDIDSVIDKVAKCCETLEYKLKE---SPETPFFYGDQPCELDAIAFGHLFSILTTTLPNMAL---AQTVQKFQHLVEFCRFVDEKYFQTRCLPN-----------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P50110-1", "uniprot_id": "SAM37_YEAST", "id": "P50110-1", "name": "Sorting assembly machinery 37 kDa subunit", "aln": "MVKGSVHLWGKDGKASLISVDSIALVWFIKLCTSEEAKSMVAGLQIVFSNNTDLSSDGKLPVLILDNGTKVSGYVNIVQFLHKNICTS--KYEKGTDYEEDLAIVRKKDRLLEYS--LLNYVDVEISRLTDYQLFLNTKNYNEYTKKLFSKLLYFPMWYNTPLQLRSQARENCEEIIGSLTLEDDEEFVESKAMESASQLAQSKTFKIAHKNKIKGKQELQQVKYN-LQFDNRLQSCVSNWLAARKKLDDSVILSSDLLFLANLYVQLGLPDGNRIRSKLEQTFGSELLNSMSNKIDDFVHRPSNNLEQRDPQFREQGNVVMSLYNLACKYI", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . : * . : . . **::.:* *. :::: :: . : :: . . .:.::: :. ::::*. : : . :. : . * . : . : :: : :: * . . . . . . : :: : : :: :. :*. ::. : :* * . :*. .:: : * : . * .:.:..: : : *. ", "identical_positions": 15, "similar_positions": 94, "identity": "4.52%" }, { "cls_id": "homologset.agr.MGI:1859660", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P98199-1", "uniprot_id": "AT8B2_MOUSE", "id": "P98199-1", "name": "Phospholipid-transporting ATPase ID", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------MTVPKEIPEKWARAG-----APPSWSQK-------------------------KPSWG------TEEERRARANDREYNEKFQYASNCIKTSKYNIVTFLPVNLFEQFQEVANTYFLFLLILQLIPQISSLSWFTTIVPLVLVLTITAVKDATDDYFRHKSDNQVNNRHSQVLI-------------------------------------------------------------------------------------------------------------------NGVLQQEQWMNVCVGDIIKLENNQFVAADLLLLSSSEPHGLCYIETAELDGETNMKVRQAIPVTSELGD-VSQLARFDGEVICEPPNNKLDKFSGTLYWKEN------KFPLSNQNMLLRGCVLRNTEWCFGLVIFAGPDTKLMQNSGRTKFKRTSIDRLMNTLVLWIFGFLVCMGVILAIGNAIWEHEVGTRFQVYLPWDEAVDSAFFS------GFLSFWSYIIILNTVVPISLYVSVEVIRLGHSYFINWDKKMFCMKKRTPAEARTTTLNEELGQVEYIFSDKTGTLTQNIMVFNKCSINGHSYGDVFDVLG------------------------------------------HKAELGERP---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------EPVDFS-FNPLADKKFLFWDSSLLEAVK-----MGDPHTHEFFRLLSLCHTVMSEEK--NEGELYYKAQSPDEGALVTAARNFGFVFRSRTPKTITVHELGTAITYQLLAILDFNNIRKRMSVIVRN------PEGKIRLYCKGADTILLDRLHP----PTQELLSSTTDHLNEYAGDGLRTLVLAYKDLDEEYYEEWARRRLQASLAQDSREDRLASIYEEVESDMMLLGATAIEDKLQQGVPETIALLTLANIKIWVLTGDKQETAVNIGYSCKMLTDDMTEVFVVT-GHTVLEVREELRKARKKMVDSSH------------------------------------------------------AVGNGF-TYQGNLSSS--------------KLTSVLEAVAGEYALVINGHSLAHALEAD-MELEFLETACACKAVICCRVTPLQKAQVVELVKKYKKAVTLAIGDGANDVSMIKTAHIGVGISGQEGIQAVLASDYSFSQFKFLQRLLLVHGRWSYLRMCKFLCYFFYKNFAFTMVHFWFGFFCGFSAQTVYDQYFITLYNIVYTSLPVLAMGVFDQDVPEQRSMEYPKLYEPGQLNLLFNKREFFICIAQGIYTSVLMFFIPYGVFAE--ATRDDGTQLADYQSFAVTVATSLVIVVSVQIGLDTGYWTAINHFFIWGSLAVYFAILFAMHSNGLFDMFPNQFRFVGNAQNTLAQPTVWLTIALTTAVCIMPVVAFRFLRLSLKPDLSDTVRYTQLVR-KKQKAQHRCMR--------------RVGRTGSRRSGYAFSHQEGFGELIMSGKNMRLSSLALSSFSTRSSSSWIESLRRKKSD----SANSPSGGAEKPLKG-----------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8I6GJC6-1", "uniprot_id": "A0A8I6GJC6_RAT", "id": "A0A8I6GJC6-1", "name": "Phospholipid-transporting ATPase", "aln": "-----------------------------------------------------------------------------------------------MLSRTVGRPSFPLRVSHGLLEPCWVRWHCVQKSAPQATLRPRTVNAPFKNGIMTVPKEMPEKWARAG-----APPSWSQK-------------------------KPSWG------TEEERRARANDREYNEKFQYASNCIKTSKYNILTFLPVNLFEQFQEVANTYFLFLLILQLIPQISSLSWFTTIVPLVLVLTITAVKDATDDYFRHKSDNQVNSRHSQVLI-------------------------------------------------------------------------------------------------------------------NGVLQQEQWMNVCVGDIIKLENNQFVAADLLLLSSSEPHGLCYIETSELDGETNMKVRQAIPVTSELGD-ISQLAKFDGEVICEPPNNKLDKFSGALYWKGN------KFPLSNQNMLLRGCVLRNTEWCFGLVIFAGPDTKLMQNSGRTKFKRTSIDRLMNTLVLWIFGFLVCMGVILAIGNAIWEHEVGTRFQVYLPWDEAVDSAFFS------GFLSFWSYIIILNTVVPISLYVSVEVIRLGHSYFINWDKKMFCMKKRTPAEARTTTLNEELGQVEYIFSDKTGTLTQNIMVFNKCSINGHSYGDVFDVLG------------------------------------------HKAELGERP---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------EPVDFS-FNPLADKKFLFWDPSLLEAVK-----MGDPHTHEFFRLLSLCHTVMSEEK--NEGELYYKAQSPDEGALVTAARNFGFVFRSRTPKTVTVHELGTSITYQLLAILDFNNIRKRMSVIVRN------PEGKIRLYCKGADTILLDRLHP----STQELLNSTTDHLNEYAGDGLRTLVLAYKDLDEEYYEEWARRRLQASLAQDSREDRLASIYEEVESDMMLLGATAIEDKLQQGVPETIALLTLANIKIWVLTGDKQETAVNIGYSCKMLTDDMTEVFIVT-GHTVLEVREELRKARKKMVDSSH------------------------------------------------------AVGNGF-TYQGNLSSS--------------KLTSVLEAVAGEYALVINGHSLAHALEAD-MELEFLETACACKAVICCRVTPLQKAQVVELVKKYKKAVTLAIGDGANDVSMIKTAHIGVGISGQEGIQAVLASDYSFSQFKFLQRLLLVHGRWSYLRMCKFLCYFFYKNFAFTMVHFWFGFFCGFSAQTVYDQYFITLYNIVYTSLPVLAMGVFDQDVPEQRSMEYPKLYEPGQLNLLFNKREFFICIAQGIYTSVLMFFIPYGVFAE--ATRDDGTQLADYQSFAVTVATSLVIVVSVQIGLDTGYWTAINHFFIWGSLAVYFAILFAMHSNGLFDMFPNQFRFVGNAQNTLAQPTVWLTIVLTTAVCIMPVVAFRFLRLSLKPDLSDTVRYTQLVR-KKQKAQHRCMR--------------RVGRTGSRRSGYAFSHQEGFGELIMSGKNMRLSSLALSSFSTRSSSSWIESLRRKKSD----SANSPSGGAEKPLKG-----------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P98198-1", "uniprot_id": "AT8B2_HUMAN", "id": "P98198-1", "name": "Phospholipid-transporting ATPase ID", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------MTVPKEMPEKWARAQ-----APPSWSRK-------------------------KPSWG------TEEERRARANDREYNEKFQYASNCIKTSKYNILTFLPVNLFEQFQEVANTYFLFLLILQLIPQISSLSWFTTIVPLVLVLTITAVKDATDDYFRHKSDNQVNNRQSQVLI-------------------------------------------------------------------------------------------------------------------NGILQQEQWMNVCVGDIIKLENNQFVAADLLLLSSSEPHGLCYIETAELDGETNMKVRQAIPVTSELGD-ISKLAKFDGEVICEPPNNKLDKFSGTLYWKEN------KFPLSNQNMLLRGCVLRNTEWCFGLVIFAGPDTKLMQNSGRTKFKRTSIDRLMNTLVLWIFGFLVCMGVILAIGNAIWEHEVGMRFQVYLPWDEAVDSAFFS------GFLSFWSYIIILNTVVPISLYVSVEVIRLGHSYFINWDKKMFCMKKRTPAEARTTTLNEELGQVEYIFSDKTGTLTQNIMVFNKCSINGHSYGDVFDVLG------------------------------------------HKAELGERP---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------EPVDFS-FNPLADKKFLFWDPSLLEAVK-----IGDPHTHEFFRLLSLCHTVMSEEK--NEGELYYKAQSPDEGALVTAARNFGFVFRSRTPKTITVHEMGTAITYQLLAILDFNNIRKRMSVIVRN------PEGKIRLYCKGADTILLDRLHH----STQELLNTTMDHLNEYAGEGLRTLVLAYKDLDEEYYEEWAERRLQASLAQDSREDRLASIYEEVENNMMLLGATAIEDKLQQGVPETIALLTLANIKIWVLTGDKQETAVNIGYSCKMLTDDMTEVFIVT-GHTVLEVREELRKAREKMMDSSR------------------------------------------------------SVGNGF-TYQDKLSSS--------------KLTSVLEAVAGEYALVINGHSLAHALEAD-MELEFLETACACKAVICCRVTPLQKAQVVELVKKYKKAVTLAIGDGANDVSMIKTAHIGVGISGQEGIQAVLASDYSFSQFKFLQRLLLVHGRWSYLRMCKFLCYFFYKNFAFTMVHFWFGFFCGFSAQTVYDQYFITLYNIVYTSLPVLAMGVFDQDVPEQRSMEYPKLYEPGQLNLLFNKREFFICIAQGIYTSVLMFFIPYGVFAD--ATRDDGTQLADYQSFAVTVATSLVIVVSVQIGLDTGYWTAINHFFIWGSLAVYFAILFAMHSNGLFDMFPNQFRFVGNAQNTLAQPTVWLTIVLTTVVCIMPVVAFRFLRLNLKPDLSDTVRYTQLVR-KKQKAQHRCMR--------------RVGRTGSRRSGYAFSHQEGFGELIMSGKNMRLSSLALSSFTTRSSSSWIESLRRKKSD----SASSPSGGADKPLKG-----------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9PDL2-1", "uniprot_id": "A0A8M9PDL2_DANRE", "id": "A0A8M9PDL2-1", "name": "Phospholipid-transporting ATPase", "aln": "------------------------------------------------------------------------------------------------------------------------------------------MKRQWDN--MTIPKDIPEKWFPVI-----LPLKRKKEG-------------------LTSSTKIRKG------AEEERRVRANDREYNEKFQYASNCIMTSKYNIITFLPVNLFEQFQEVANTYFLFLLILQLIPQISSLSWFTTIVPLVLVLSITAVKDATDDYFRHKSDNQVNNRQSQVLI-------------------------------------------------------------------------------------------------------------------GGILQKEKWMNVRVGDIIKLENNQFVAADLLLLSSSEPHGLCYIETAELDGETNMKVRQSLSVTSELGD-PNNLAQFDGEVVCEPPNNKLDRFCGTLYWREC------KYPLSNQNMLLRGCVLRNTESCYGLVIFAGPDTKLMQNSGRTKFKRTSIDRLMNTLVLWIFGFLVCMGVILAIGNAVWEKEVGALFQSFLPWDPPVDNFLFS------AFLSFWSYVIILNTVVPISLYVSVEVIRLGHSYFINWDRRMFCSRSNTAAEARTTTLNEELGQVEYIFSDKTGTLTQNIMTFNKCSINGHAYGEVVNIL---------------------------------------------AAQQKRV---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------QPLDFSSWNPLADRGFCFYDQSLLEAVM-----VGDPAVHEFFRVLSLCHTVMSEEK--SEGELVYKAQSPDEGALVTAARNFGFVFRSRTPGTITTQELGKAVTYTLLAILDFNNIRKRMSVIVRN------PEGRIRLYCKGADTVLLERLHS----CNHEVMTITSDHLNEYAVDGLRTLAVAYRDLSEEQWDEWSERFRGADKATDCREDRLAAAYEEIEQDMMLLGATAIEDKLQEGVPETIAILSLANIKIWVLTGDKQETAVNIGYSCKMLTDDMTEVFIVN-GHTVQSVREELRKARERMLESARTRDGGKEAEAQGWSGA-------------------------------------CAFGNGC-GAGAAAAAANWAPDESKCPPAQAPPSSLLESISGEFALIISGHSLAHALEAD-MEREFLETACACRAVICCRVTPLQKALVVELVKRHKKAVTLAIGDGANDVSMIKTAHIGVGISGQEGIQAVLASDYSFSQFRFLQRLLLVHGRWSYLRMCRFLCYFFYKNFAFTMVHFWFGFFCGFSAQTVYDQYFITLYNIVYTSLPVLAMGIFDQDVPEQRSLEYPKLYEPGQLNLLFNKREFFICIAQGIYTSVVLFFIPYSVLSH--ATQSNGVPLADYQTFAVTTATALVIVVSVQIALDTGYWTAINHFFVWGSLGTYFTILFAMHSSILFSIFPKQFHFLGSAHNTLGQPVVWLTIALATVICIAPVLAFRFLKLDLKPQLSDTVRYTQLVLQKKRKPGGRAARGVGSTGAAGGSGLGRLGRGGSRRSGYAFAHQEGFGELITSGKNMRLSSLALATFASRHSSSWIDTLRRKKHTNNTGAQNTPPTGDDITTSSQVPPISTASTPNVQQDSAAGDAGQASNEVAFTHSPEDIALSVVRDRDAGGCSAGSVQESAIVWKGIGARVSGANSPGPPPIEEETSYGE", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VGD4-1", "uniprot_id": "Q9VGD4_DROME", "id": "Q9VGD4-1", "name": "Phospholipid-transporting ATPase", "aln": "----------------------MIGGRRCSEAARRLRRRPDTLELSVLGGQPIETELQEDNERTPTKGAGNVDEPGIEAPEASCSAPSKRTRWFQFARSSKNRRKRLHCNEDEDVKQPERRNSDLEGSPRACLAQPEGMNIGSSTQTIATPLMIGDSFYSLAPGGGNPPPNKSDDQELYKQRDPSVTSESKSVPSLRRLSQIRRRRSSYYFSENERRIRANDKEFNAQFKYHNNYIKTSKYSLFTFLPFNLLEQFQRLANFYFLCLLVLQLIPAISSLTPVTTAIPLIGVLTLTAVKDAYDDIQRHISDSQVNNRKSKTLR-------------------------------------------------------------------------------------------------------------------NGKLVEAKWSEVQVGDVIRLDNNQFVAADTLLLSTSEPNGLCFIETAELDGETNLKAKQCLTETIELGDRHDSLWNFNGEIICERPNNLLNKFDGTLIWRGQ------RFALDNEKILLRGCVLRNTQWCYGVVVFAGVDTKLMQNSGKTQFKSTGVDRLLNFIIIGIVLFLVSICALFAIGCAIWEGLIGQHFQLYLPWEHIIPKDYIPTGATVIGLLVFFSYAIVLNTVVPISLYVSVEVIRFVQSFLINWDEEMYYPTTNTYAKARTTTLNEELGQIQYIFSDKTGTLTQNIMTFNKCSINGRSYGDVIDLRTGELVEITEQQTIFQNSNTNNRPSPLSGAIVAPPAAPPPIILVHKAEVHAKKTSMVVTSSGEAQVLPDRPRSDIERSAPPMDASEKRPGLKHVRYSAPSRSQDADAGRLSPRLDGSGGLSPPVGNEERRISGGFKRSGAGCMQRQLSRTSSCDKVKILHDSQQTETHNMHHSSHNRKRLVKIRFKKAPSTATLGVVISQLEHHLDEEPQSTSTLSTTKHHHHRSKAFATNWSSSPHRVHALQSVDFS-ANPHHESDFRWYDRTLLDAVR-----SDEEHSHVFFRLLALCHTVMAET---VDGKLEYQAQSPDEAALVSAARNFGFVFRTRTPNSITIEVMGQTEEYELLNILDFNNVRKRMSVILRR------GDS-MVLYCKGADNVIYDRLHG----GQEDLKARTQDHLNKFAGEGLRTLALAERRLTEQYYNDWRSRQQEAALSMDSREQKLNAIYEEIESEMQLVGVTAIEDKLQDGVPKSIANLQNAGIKIWVLTGDKQETAINIGYSCQLLTDELADVFIVD-GNSVEEVEKQLRQFKESIKIYNRFRPGGFDPFDRLNSDSNMDPLSVTMTQTSAFMQETNLPPTPPPPPAISVVTFRWDEKNKD-NKGGPDSAECNNLFGDEKGSEDGGTASIVVDENTGFALVVNGHSLVHCLSPE-LENKFLDIASQCKAVICCRVTPLQKALVVELIKRAKNAVTLAIGDGANDVSMIKAAHIGVGISGQEGLQAVLSSDYSIAQFRYLERLLLVHGRWSYYRMCKFLRYFFYKNFAFTLCHCWYSLFCGFSAQTVFDPMFISVYNLFYTSLPVLALGVFEQDVSDKNSLEFPRLYTPGLKSELFNIREFIYSVLHGAFTSLVLFLIPYGVYKD--GVSANGFVVSDHMTLGAVVATILIVDNTAQISLYTSYWTVVNHVTIWGSLVWYFVLDYFYN-------YVIGGPYVGSLTQAMKDLTFWVTMLITVMALVAPVLAYKFYLLDVHPSLSDKIRQKSLKKIHSRASSDVRRTASS-----------RRGRR-SVRSGYAFAHQEGFGRLITSGKIMHKLPQDFA-FPLGLGTKKTQVLHNNLNS----ADGPNSKGNNVTGHHMVNNNTNMRHNQNQNHSSMADITADG-------------------RGNGGD------------DGRGSGGSDDMSPRAPCQDLDTINL-", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q12675-1", "uniprot_id": "ATC4_YEAST", "id": "Q12675-1", "name": "Phospholipid-transporting ATPase DNF2", "aln": "MSSPSKPTSPFVDDIEHESGSASNGLSSMSPFDDSFQFEKPSSAHGNIEVAKTGGSVLKRQSKPMKDISTPDLSKVTFDGIDDYSNDNDINDDDELNGKKTEIHEHENEVDDDLHSFQATPMPNTGG--FEDVELDNNEGSNNDSQADHKLKRVRFGTRRNKSGRIDINRSKTLKWAKKNFHNAIDEFSTKEDSLENSALQNRSDELRTVYYNLPLPEDMLDEDGLPLAVYPRNKIRTTKYTPLTFFPKNILFQFHNFANIYFLILLILGAFQIFGVTNPGFASVPLIVIVIITAIKDGIEDSRRTVLDLEVNNTRTHILSGVKNENVAVDNVSLWRRFKKANTRALIKIFEYFSENLTAAGREKKLQKKREELRRKRNSRSFGPRGSLDSIGSYRMSADFGRPSLDYENLNQTMSQANRYNDGENLVDRTLQPNPECRFAKDYWKNVKVGDIVRVHNNDEIPADMILLSTSDVDGACYVETKNLDGETNLKVRQSLKCSKIIKS-SRDITRTKFWVESEGPHANLYSYQGNFKWQDTQNGNIRNEPVNINNLLLRGCTLRNTKWAMGMVIFTGDDTKIMINAGVTPTKKSRISRELNFSVILNFVLLFILCFTAGIVNGVYYKQK-PRSRDYFEFGTIGGSASTN------GFVSFWVAVILYQSLVPISLYISVEIIKTAQAIFIYTDVLLYNAKLDYPCTPKSWNISDDLGQIEYIFSDKTGTLTQNVMEFKKCTINGVSYGRAYTEALAGLRKRQGVDVESEGRR-------------------------EKEEIAKDRE----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------TMIDELRSMSDNTQFCPEDLTFVSKEIVEDLKGSSGDHQQKCCEHFLLALALCHSVLVEPNKDDPKKLDIKAQSPDESALVSTARQLGYSFVGSSKSGLIVEIQGVQKEFQVLNVLEFNSSRKRMSCIIKIPGSTPKDEPKALLICKGADSVIYSRLDR--TQNDATLLEKTALHLEEYATEGLRTLCLAQRELTWSEYERWVKTYDVAAASVTNREEELDKVTDVIERELILLGGTAIEDRLQDGVPDSIALLAEAGIKLWVLTGDKVETAINIGFSCNVLNNDMELLVVKASGEDVEEFGSDPIQVVNNLVTKYLR------------------------------------------------------EKFGMSGSEEELK----------------EAKREHGLPQGNFAVIIDGDALKVALNGEEMRRKFLLLCKNCKAVLCCRVSPAQKAAVVKLVKKTLDVMTLAIGDGSNDVAMIQSADVGVGIAGEEGRQAVMCSDYAIGQFRYVTRLVLVHGKWCYKRLAEMIPQFFYKNVIFTLSLFWYGIYNNFDGSYLFEYTYLTFYNLAFTSVPVILLAVLDQDVSDTVSMLVPQLYRVGILRKEWNQTKFLWYMLDGVYQSVICFFFPYLAYHKNMVVTENGLGLDHRYFVGVFVTAIAVTSCNFYVFMEQYRWDWFCGLFICLSLAVFYGWTGIWTSS------SSSNEFYKGAARVFAQPAYWAVLFVGVLFCLLPRFTIDCIRKIFYPKDIEIVREMWLRGDFDLYPQGYDPTDPSRPR-------INEIRPLTD-FKEPISLDTHFDGVSHSQETIVTEEIPMSILNGEQGSRKGYRVSTTLER--RDQLSPVTTTNNLPRRSMASARGNKLRTSLDRTREEMLANHQLDTR------------------------------YSVERARASLDLPGINHAETLLSQRSRDR-", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P32660-1", "uniprot_id": "ATC5_YEAST", "id": "P32660-1", "name": "Phospholipid-transporting ATPase DNF1", "aln": "MSG----------------TFHGDGHAPMSPFEDTFQFEDNSSNE-DTHIAPT----------HFDDGATSNKYSRPQVSFNDETPKNKREDAEEFT--------FNDDTEYDNHSFQPTPKLNNGSGTFDDVELDNDSGEPHTN--YDGMKRFRMGTKRNKKGNPIMGRSKTLKWARKNIPNPFEDFTK--DDIDPGAIN-RAQELRTVYYNMPLPKDMIDEEGNPIMQYPRNKIRTTKYTPLTFLPKNILFQFHNFANVYFLVLIILGAFQIFGVTNPGLSAVPLVVIVIITAIKDAIEDSRRTVLDLEVNNTKTHILEGVENENVSTDNISLWRRFKKANSRLLFKFIQYCKEHLTEEGKKKRMQRKRHELRVQKTVGTSGPRSSLDSIDSYRVSADYGRPSLDYDNLEQGAGEAN-------IVDRSLPPRTDCKFAKNYWKGVKVGDIVRIHNNDEIPADIILLSTSDTDGACYVETKNLDGETNLKVRQSLKCTNTIRT-SKDIARTKFWIESEGPHSNLYTYQGNMKWRNLADGEIRNEPITINNVLLRGCTLRNTKWAMGVVMFTGGDTKIMLNSGITPTKKSRISRELNFSVVINFVLLFILCFVSGIANGVYYDKK-GRSRFSYEFGTIAGSAATN------GFVSFWVAVILYQSLVPISLYISVEIIKTAQAAFIYGDVLLYNAKLDYPCTPKSWNISDDLGQVEYIFSDKTGTLTQNVMEFKKCTINGVSYGRAYTEALAGLRKRQGIDVETEGRR-------------------------EKAEIAKDRD----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------TMIDELRALSGNSQFYPEEVTFVSKEFVRDLKGASGEVQQRCCEHFMLALALCHSVLVEANPDNPKKLDLKAQSPDEAALVATARDVGFSFVGKTKKGLIIEMQGIQKEFEILNILEFNSSRKRMSCIVKIPGLNPGDEPRALLICKGADSIIYSRLSRQSGSNSEAILEKTALHLEQYATEGLRTLCIAQRELSWSEYEKWNEKYDIAAASLANREDELEVVADSIERELILLGGTAIEDRLQDGVPDCIELLAEAGIKLWVLTGDKVETAINIGFSCNLLNNEMELLVIKTTGDDVKEFGSEPSEIVDALLSKYLK------------------------------------------------------EYFNLTGSEEEIF----------------EAKKDHEFPKGNYAIVIDGDALKLALYGEDIRRKFLLLCKNCRAVLCCRVSPSQKAAVVKLVKDSLDVMTLAIGDGSNDVAMIQSADVGIGIAGEEGRQAVMCSDYAIGQFRYLARLVLVHGRWSYKRLAEMIPEFFYKNMIFALALFWYGIYNDFDGSYLYEYTYMMFYNLAFTSLPVIFLGILDQDVNDTISLVVPQLYRVGILRKEWNQRKFLWYMLDGLYQSIICFFFPYLVYHKNMIVTSNGLGLDHRYFVGVYVTTIAVISCNTYVLLHQYRWDWFSGLFIALSCLVVFAWTGIWSSA------IASREFFKAAARIYGAPSFWAVFFVAVLFCLLPRFTYDSFQKFFYPTDVEIVREMWQHGHFDHYPPGYDPTDPNRPK-------VTKAGQHGEKIIEGIALSDNLGGSNYSRDSVVTEEIPMTFMHGEDGSPSGYQKQETWMTSPKETQDLLQSPQFQQAQTFGRGPSTNVRSSLDRTREQMIATNQLDNR------------------------------YSVERARTSLDLPGVTNAASLIGTQQNN--", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . . . . : : *.: * * * *:**. .**:* *:: **:..** *** *::* : :. . : :**: :: :**:**. :* * * :**. ::: * : : * * ***::::.**: :.** :***:*: .* *::** :******:*.:*.: : : .: . . : .* *: * : * : *: . .: :::*****.****: . *:*:*:* ***:* *:* * * : :.* :* :: . :*. : .* .:: : : . .:: *: *: :::******:***:*: :: :* * :: . .:: .:.::***::*************:* *:**:*** :** . : :* . . : . :: : : . *: *:***:*: * :* :******.***::**:.*: * : : . * : :* :*:**. ***** *:: : * *****.:: .** : * **:::* :***** :* : * . :: * * : **:.* : :* :: *:* *****:**:***. * * *.**:******* ***:***:**::*.::: :.: *. * .. .: : . : :*:::.*.:* .* : :. :** . *:**:****:* *** **:*:* ..:*******:***:**::*.:*:**:*:** ***:.***::.**::: **:****:*.* *:..:: *****. *:: *:.:: .*... ::: :: .**: :**:**: :.:::*** : *: *:** * :* :*: : .* : *:: *::** . . . :* : . ... .:: : . : : * . . : * : : . * .: : . : * .: . * : :* . . :: . :. * . : :: : .: . . ", "identical_positions": 313, "similar_positions": 347, "identity": "16.05%" }, { "cls_id": "homologset.agr.MGI:1859661", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9QZW0-1", "uniprot_id": "AT11C_MOUSE", "id": "Q9QZW0-1", "name": "Phospholipid-transporting ATPase 11C", "aln": "-----------------------------------------MFRRTLN--RLCAGEEK--------------------------RVGTRTVFVGNHPISGTEP-----------------------------YIAQRFCDNRIVSSKYTLWNFLPKNLFEQFRRIANFYFLIIFLVQVTVDTPTS-PVTSGLPLFFVITVTAIKQGYEDWLRHRADNEVNKSAVYIIE--------------------------------------------------------------NAKRVRKESEKIKVGDVVEVQANETFPCDLILLSSCTTDGTCYVTTASLDGESNCKTHYAVRDT-IALCTAESIDNLRATIECEQPQPDLYRFVGRISIYSNS-----IEAVARSLGPENLLLKGATLKNTKKIYGVAVYTGMETKMALNYQGKSQKCSAVEKSINAFLIVYLFILLTKAAVCTTLKYVWQSSPYNDEPWYNQKTQKERETFQVLKMFTDFLSFMVLFNFIIPVSMYVTVEMQKFLGSFFISWDKDFFDEEINEGALVNTSDLNEELGQVDYVFTDKTGTLTENSMEFIECCIDGHKYKG--TTQEVDGLSQTDGPL-AYFDKADKNREALFLRALCLCHTVEMKTN----------------------------DDVDGPVEGAGFT-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------YISSSPDEIALVKGAKRFGFTFLGNQNGYIRVENQR-----------KEIEEYELLHTLNFDSVRRRMSVIVRT--QKGDILLFCKGADSSIFPRVHSH---------------------------------------------------------------------------------------------------------------------------------------------------------------------QIELTKDHVERNAMDGYRTLCVAFKEIPPDDFERINAQLVEAKMALQDREEKLEKVFDEIETNMNLIGATAVEDKLQDQAAETIEALHAAGLKVWVLTGDKMETAKSTCYACRLFQTNTELLELTTKTIEES-ERKEDRLHELLIEYRKKLLHEFP-KSTRSLKKAWTEHQEYGLIIDGSTLSLILNSSQDCSSNNYKSIFLQICMKCTAVLCCRMAPLQKAQIVRMVKNLKGSPITLSIGDGANDVSMILESHVGIGIKGKEGRQAARNSDYSVPKFKHLKKLLLVHGHLYYVRIAHLVQYFFYKNLCFILPQFLYQFFCGFSQQPLYDAAYLTMYNICFTSLPILAYSLLEQHINIDTLTADPRLYMKITGNAMLQLGPFLHWTFLAAFEG-TVFFFGTYFLFQTSSLEDNGKIYGNWTFGTIVFTVLVFTVTLK-LALDTRFWTWINHFVIWGSLAFYVFFSFFWGGIIWPFLKQQRMYFVFAQMLCSVSTWLAIILLIFISLFPEILLIVVKNVRRRSARRNLSCR-----------------------RASDSLSARPSVRPLLLRTFSDESNIL----------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8I6AFP3-1", "uniprot_id": "A0A8I6AFP3_RAT", "id": "A0A8I6AFP3-1", "name": "Phospholipid-transporting ATPase", "aln": "-----------------------------------------MFRRTLN--RLCAGEEK--------------------------RVGTRTVFVGNHPISGTEA-----------------------------YIAQRFCDNRIVSSKYTLWNFLPKNLFEQFRRIANFYFLIIFLVQVTVDTPTS-PVTSGLPLFFVITVTAIKQGYEDWLRHRADNEVNKSTVYIIE--------------------------------------------------------------NAKRVRKESEKIKVGDVVEVQADETFPCDLILLSSCTTDGTCYVTTASLDGESNCKTHYAVRDT-IELCTAESIDNLRAAIECEQPQPDLYKFVGRISIYSNS-----IEAVARSLGPENLLLKGATLKNTKKIYGVAVYTGMETKMALNYQGKSQKRSAVEKSINAFLIVYLFILLTKAAVCTTLKYVWQSTPYNDEPWYNQKTQKERETFKVLKMFTDFLSFMVLFNFIIPVSMYVTVEMQKFLGSFFISWDKDFFDEEINEGALVNTSDLNEELGQVDYVFTDKTGTLTENSMEFIECCIDGHKYKG--TTQEVDGLSQIDGPL-AYFDKADKNREELFLRALCLCHTVEIKTN----------------------------DAVDGPIEGAQFT-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------YISSSPDEIALVKGAQKFGFTFLGNWNGHIRVENQR-----------KEIEEYELLHTLNFDSVRRRMSVIVRT--QGGDILLFCKGADSSIFPRVHSH---------------------------------------------------------------------------------------------------------------------------------------------------------------------EIDLTKVHVERNAMDGYRTLCVAFKEIPPDDFERINVQLIEAKMALQDREEKLEKIFDVIETNMNLIGATAVEDKLQDQAAETIEALHAAGLKVWVLTGDKMETAKSTCYACRLFQTNTELLELTTKTIEES-ERKEDRLHELLIEYRKKLLHEFP-KSTRSLKKAWTEHQEYGLIIDGSTLSLILNSSQDCSSNNYKSIFLQICMKCTAVLCCRMAPLQKAQIVRMVKNLKGSPITLSIGDGANDVSMILESHVGIGIKGKEGRQAARNSDYSVPKFKHLKKLLLAHGHLYYVRIAHLVQYFFYKNLCFILPQFLYQFFCGFSQQPLYDAAYLTMYNICFTSLPILAYSLLEQHINIDALTADPRLYMKITGNAMLQLGPFLYWTFLAAFEG-TVFFFGTYFLFQTTSLEDNGKIYGNWTFGTIVFTVLVFTVTLK-LALDTRFWTWINHFVIWGSLAFYVFFSFFWGGIIWPFLKQQRMYFVFAQMLSSVSTWLAIILLIFISLFPEILLIVVKNVRRRSARRNLSCR-----------------------RASDSLSARPSVRPLLLRTFSDESNIL----------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8NB49-1", "uniprot_id": "AT11C_HUMAN", "id": "Q8NB49-1", "name": "Phospholipid-transporting ATPase IG", "aln": "----------------------------------------MQMVPSLPPASECAGEEK--------------------------RVGTRTVFVGNHPVSETEA-----------------------------YIAQRFCDNRIVSSKYTLWNFLPKNLFEQFRRIANFYFLIIFLVQVTVDTPTS-PVTSGLPLFFVITVTAIKQGYEDCLRHRADNEVNKSTVYIIE--------------------------------------------------------------NAKRVRKESEKIKVGDVVEVQADETFPCDLILLSSCTTDGTCYVTTASLDGESNCKTHYAVRDT-IALCTAESIDTLRAAIECEQPQPDLYKFVGRINIYSNS-----LEAVARSLGPENLLLKGATLKNTEKIYGVAVYTGMETKMALNYQGKSQKRSAVEKSINAFLIVYLFILLTKAAVCTTLKYVWQSTPYNDEPWYNQKTQKERETLKVLKMFTDFLSFMVLFNFIIPVSMYVTVEMQKFLGSFFISWDKDFYDEEINEGALVNTSDLNEELGQVDYVFTDKTGTLTENSMEFIECCIDGHKYKG--VTQEVDGLSQTDGTL-TYFDKVDKNREELFLRALCLCHTVEIKTN----------------------------DAVDGATESAELT-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------YISSSPDEIALVKGAKRYGFTFLGNRNGYMRVENQR-----------KEIEEYELLHTLNFDAVRRRMSVIVKT--QEGDILLFCKGADSAVFPRVQNH---------------------------------------------------------------------------------------------------------------------------------------------------------------------EIELTKVHVERNAMDGYRTLCVAFKEIAPDDYERINRQLIEAKMALQDREEKMEKVFDDIETNMNLIGATAVEDKLQDQAAETIEALHAAGLKVWVLTGDKMETAKSTCYACRLFQTNTELLELTTKTIEES-ERKEDRLHELLIEYRKKLLHEFP-KSTRSFKKAWTEHQEYGLIIDGSTLSLILNSSQDSSSNNYKSIFLQICMKCTAVLCCRMAPLQKAQIVRMVKNLKGSPITLSIGDGANDVSMILESHVGIGIKGKEGRQAARNSDYSVPKFKHLKKLLLAHGHLYYVRIAHLVQYFFYKNLCFILPQFLYQFFCGFSQQPLYDAAYLTMYNICFTSLPILAYSLLEQHINIDTLTSDPRLYMKISGNAMLQLGPFLYWTFLAAFEG-TVFFFGTYFLFQTASLEENGKVYGNWTFGTIVFTVLVFTVTLK-LALDTRFWTWINHFVIWGSLAFYVFFSFFWGGIIWPFLKQQRMYFVFAQMLSSVSTWLAIILLIFISLFPEILLIVLKNVRRRSARRNLSCR-----------------------RASDSLSARPSVRPLLLRTFSDESNVL----------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9PUH0-1", "uniprot_id": "A0A8M9PUH0_DANRE", "id": "A0A8M9PUH0-1", "name": "Phospholipid-transporting ATPase", "aln": "-----------------------------------------MLRRRLN--RLCGGDER--------------------------RVDSRTIYVGHRPCPDTEA-----------------------------FIPPKFCDNRIVSSKYTVWNFLPKNLFEQFRRIANFYFLIIFLVQVIVDTPTS-PVTSGLPLFFVITVTAIKQGYEDWLRHKADNEVNKYPVTVLE--------------------------------------------------------------DGRSVKKESEKIKVGDVVEVVEDETFPCDLILLQSSREDGTCFVTTASLDGESNHKTHYTVPD------IERDLQVLTAAIECEQPQPDLYKFVGRMHIYKPE-----QEEAVRSLGPENLLLKGATLKNTKEIYGVAVYTGMETKMALNYQGKSQKRSAVEKSINAFLLVYLCILISKAVVCTTLKYVWQSKEGQDEPWYNEKTQKEKETNMYLKMFTDFLSFMVLFNFIIPVSMYVTVEMQKFLGSFFIKWDNDFFDPEIEEGALVNTSDLNEELGQVEYVFTDKTGTLTQNNMEFIECCIDGFQYRHRDAHGELDGFTVTDGPLNKLQEKAGREKEELFLRALCLCHTVQVKEETL----------------------SDQIDGIDGVLPKAEEER---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------GFIASSPDEVALVKGAMEYGFTFLGLENKNMKIRNRQ-----------NDIEEYKLLHVLNFDPVRRRMSVIVQT--KSGDTLLFCKGADSSIFPRVRPE---------------------------------------------------------------------------------------------------------------------------------------------------------------------EVDRIRLQVERNATDGYRTLCVAYKQLSAEEYALADTGLREARLALQDREEKLMAMYNQVETGMSLIGATAVEDRLQEEAAETMEALQGAGMKIWVLTGDKMETAKSTCYACRLFQRGTELLELTVRTLEDGRSKREDRLLELLRDYHRRAVQDAPPVKTGVVTRSWSANQEYGFIIDGATLSLVMNPPRDADASLYRGLFLQICQNCTAVLCCRMAPLQKAQIVKMVKNCKGSPITLSIGDGANDVSMILEAHVGIGIKGKEGRQAVRNSDYAIPKLKHLKKLLLAHGHLYYVRIAHLVQYFFYKNLCFILPQFLYQFFCGYSQQPLYDAAYLTMYNICFTSMPILAYSLLEQHIAIEILLDNATLYREIAKNAMLRWRPFLYWTVLGIFQG-LLFFFGVRFLFSNPALQDNGQVFGNWSYGTIVFTVLVFTVTLK-LALDTRHWTWINHFVIWGSLAFYVFFSFFWGGIIWPFLKQQRLYFVFANMLSSVSAWLVIIILILLSLLPEILLAVLRKPKGPHSRQKKPGQS----------------------NVGGIPSSQSSARPLLMRTFSDESNTVI---------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VXG7-1", "uniprot_id": "Q9VXG7_DROME", "id": "Q9VXG7-1", "name": "Phospholipid-transporting ATPase", "aln": "---------------------------------------------------MGADKKK--------------------------SADPLRIQIGG---IESRQ-----------------------------QKPL----NRVTTTKYTWFTFLPLNFYEQFRRAVYFYFLIITIVSFFVNETIS-PLVSLLPLLFVMIITALKEGLEDYSRSKSDKLVNTARVTVIR--------------------------------------------------------------NGKEEIINSQFIVPGDLVVVRNDGDVPCDLVLLQSSSADRKCFVNTANLDGETNLKTICVPTNY-LLAGDHELQG--KDCIVCEPSSADLYTFNGRLELRSGNDGAGSSAGDALPLTIDNLLLRGVRVKSTERVVGCAIYTGMHTKLQLNSRYTGNKSASSEKYINRFMVALIVGMIVVVVVLYLIERHKEAKIVPTMPYQGPPTN----FNSAWQIFEDFLSFLLLFNYMVPISAYMNIEVYRIFGMHFMHNDLHLYDEETDQPCRVNASNLNEELGQVNILFSDKTGTLTKNLMKFVNCYVPGTNYQLQNTHLVSE---GTDEKF--ELEKLDAD-AAVLFEALAVCHTVEVLQ-------------------EVGDKTLESSESVSEQSHLMSRN------------------------------------------------IVDR-------------------------------------------------------------------------------------------------------------------------------------------YQASSPDEKALLEGCASLGLVYEGQENDVLSICRYP----------SAEKVQFKRLHVLEFSSERQRMSVIVRD--QSDTIWLYSKGAESAIFPRCKAS--------------------------------------------------------------------------------------------------------------------------------------------------------------------PLVEQTDAQITKYAQNGLRTMAVGRRMLTDDELFHFEELYRKANTQLSNRNELIASCYETVENELDLLGATALEDALQEHVGETLEALQAAGLKIWVLTGDKVETAYNIGLACRHIPRGSKQHFIINTTEPAE-------LLARLD------MIGDD--------------EPEVLIVDGTTITALLEHTP--------RQFADLALRCRAVLCCRLSPLQKSEIVTLIKR-RKKYITAAIGDGANDVSMIQEAHIGIGITGREGKQAARCADFSIARFEMLRRLFLVHGHYNSQRLAFLVLFYCYKNIIITGCMALYQVYDLYSATNVYNSIYLWLFDIVYISFSFTVLAICDKDYSEETLLSHPELYKPLAHNRQASMGVFSLWILNGFVQCFIIFFFTYAMLNDANVLFNGGQTASFQTFGTMLITIIVIVGNLK-LLLVAHYMTYRNFAMILASIAAFMLTTYLY-----NLYTSGELYDVYNQFLSSLPIWLFTIICSVACLLPDFVIKVVN----------------------------------------------DMYRKVPLKSKPVV--------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VXG6-1", "uniprot_id": "Q9VXG6_DROME", "id": "Q9VXG6-1", "name": "Phospholipid-transporting ATPase", "aln": "----------------------------------MNFFGHDHLSGFRRIDRLGAHRQTPWADQESFHLKDAFLWNWHKGSRVSTINDWLQIQIGGPQDIKKKR-----------------------------PKGQ----NRIKSTKYTLITFLPQNLLEQFRRIANFYFLVMTIISLLIDSPVS-PMTSLLPLVFVIAVTAAKQGYEDILRYRTDNVVNSSPVTVIR--------------------------------------------------------------DGKEAIIKSQDVIPGELIVVERDCDVPCDLVLLRSTDPHGKCFITTANLDGESNLKTLMVPRDL-PTVDLPEMHK--LGIIECESPTTDLYSFNGKIELKGGE-------GRVLPLSTENVLLRGSRVKNTECVIGCAVYTGMISKLQLNSRLTRNKNASSETYINRFLIVILVALIAIVTLLYFLKRYNELFVIPKLTYLGDATD----SYSVKQFLQDYLSFLILFNYLIPISLYVTIELQRVIGSWFMEWDLELYENETDQPCVVNTSNLNEELGQINILFSDKTGTLTKNEMNFQQCSINGNKFLFKKTRLEDE---ETKALL--DINKFSAN-QRVFFQALSICHTVQVASGSLEQADAGTAKREPVTAIKSGPPEMYSISDITEESHNASQQSELNVGHTIDNSVSAHPNGVNSTIISSDVNPLLVSDDGYGVERRKRPVVIKRSPNFARSNRMNNGAASDLNINQTDPNTVTNGVEPTTNFRPISLQFRRSTSEKDLQQSWEAPSGQAPGHRRAHSYGAPNAYLTNPVTASTPPAGVLFRSPSTTSRESYAAPTFTRQPTILVRAESQRRKNEIRDFIFTLDYQASSPDEKALVEACANLGMVYTGDDDETLRVRIVPPHMDYKRPFAKPREETFQRLHVLEFTSDRKRMSVIVRD--TDGKKWIYTKGAESYVFPLCANSSA------------------------------------------------------------------------------------------------------------------------------------------------------------------ELVTKTDAHISDFARLGLRTLAIARRLISEEEYQDFLVELAQANSSLENRKQLSEECYAKIESNLDLLGATAVEDALQDDVADTLVSLQAAGIKIWVLTGDKVETALNIALSCGHIPPDAKKYFIMECKNREE-------MLLHLNALDREIIFGIG--------------QECALLIDGKSLGVALAEAS--------SEFRDVAVKCTAVLCCRLSPLQKSEVVSLIKSSNENYNTASIGDGANDVSMIQEAHVGIGIMGREGRQAARCADFAFAKFCMLKRLLLVHGHYHSVRLSLLVLYFFYKNIVFMGIMFLFQFHTLFSSSSVYDSLFLTLYNVIYTSLPILFIAISEKPYTEEKLMRTPQLYKKNTDNKQLHWPYFLMWVLFAIYHSVIIFYFAFCFFYYNNVLLNYGQTVAFSCFGTLLMWTVVVVVNLK-LWLESMYLSFWYIFTIIISILGFVVTTVIYN--VINLDYDTDIYWAYNNLLASLPVWLWIIVTCVACLVPDYTIRMLQRAL----------------------------------NIKSFSIFPGKQRKLKMREKFESTYL-----------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q12674-1", "uniprot_id": "ATC8_YEAST", "id": "Q12674-1", "name": "Probable phospholipid-transporting ATPase DNF3", "aln": "MGIADGQRRRSSSLRTQMFNKHLYDKYRGRTDDEIELEDINESKTFSGSDNNDKDDRDETSGNYAAEEDYEMEEYGSPDVSYSIITKILDTILDRRRTFHSKDGRHIPIILDHNAIEYKQAATKRDGHLIDERFNKPYCDNRITSSRYTFYSFLPRQLYAQFSKLANTYFFIVAVLQMIPGWSTTGTYTTIIPLCVFMGISMTREAWDDFRRHRLDKEENNKPVGVLVKDGNNDAQEVYTLPSSVVSSTAYLTKSAAAENNPPLNDDRNSSQGHFLDTHFNNFELLKNKYNVHIHQKKWEKLRVGDFVLLTQDDWVPADLLLLTCDGENSECFVETMALDGETNLKSKQPHPELNKLTKAASGLANINAQVTVEDPNIDLYNFEGNLELKNHRN----DTIMKYPLGPDNVIYRGSILRNTQNVVGMVIFSGEETKIRMNALKNPRTKAPKLQRKINMIIVFMVFVVATISLFSYLGHVLHKKKYID------QNKAWYLFQADAGVAPTIMSFIIMYNTVIPLSLYVTMEIIKVVQSKMMEWDIDMYHAETNTPCESRTATILEELGQVSYIFSDKTGTLTDNKMIFRKFSLCGSSWLHNVDLGNSEDNFEDNRDNTNSLRLPPKAHNGSSIDVVSIGDQNVLDRLGFSDAPIEKGHRPSLDNFPKSRNSIEYKGNSSAIYTGRPSMRSLFGKDNSHLSKQASVISPSETFSENIKSSFDLIQFIQRYPTALFSQKAKFFFLSLALCHSCLPKKTHN----------------------------------------------------------------------------------------------------------------ESIGEDSIEYQSSSPDELALVTAARDLGYIVLNRNAQILTIKTFPDGFDG-----EAKLENYEILNYIDFNSQRKRMSVLVRMPNQPNQVLLICKGADNVIMERLHDRELAAKKMADICTSTKERKDAEAELVLQQRKSLERMVDEEAMARTSLRNSLSSVPRASLSLQAVRKSLSMKNSRTRDPEKQIDSIDQFLETVKKSDQEIGSVVNKSRKSLHKQQIEKYGPRISIDGTHFPNNNVPIDTRKEGLQHDYDTEILEHIGSDELILNEEYVIERTLQAIDEFSTEGLRTLVYAYKWIDIGQYENWNKRYHQAKTSLTDRKIKVDEAGAEIEDGLNLLGVTAIEDKLQDGVSEAIEKIRRAGIKMWMLTGDKRETAINIGYSCMLIKDYS--TVVILTTTDEN-------IISKMNAVSQEVDSGNI--------------AHCVVVIDGATMAMFEGNPT------YMSVFVELCTKTDSVICCRASPSQKALMVSNIRNTDPNLVTLAIGDGANDIAMIQSADIGVGIAGKEGLQASRVSDYSIGQFRFLLKLLFVHGRYNYIRTSKFMLCTFYKEITFYFTQLIYQRYTMFSGSSLYEPWSLSMFNTLFTSLPVLCIGMFEKDLKPMTLLTVPELYSYGRLSQGFNWLIFMEWVILATTNSLIITFLNVVMWGMSSLSDN-----TMYPLGLINFTAIVALINVKSQFVEMHNRNWLAFTSVVLSCGGWLVWCCALPILNNTDQIYDVAYGFYNHFGKDITFWCTSLVLALLPITLDIVYKTFKVMIWPSDSDIFAELEQKSDIRKKLELGAYSEMRQGWTWDKDPSTFTRYTDKVLSRPRTNSRASAKTHNSSIYSMSNGNVDHSSKKNFFGNSSKKSSERYEVLPSGKLIKRPSLKTQSSKDSIGGNITTKLTKKLKLPSRNVEDEDVNQIIQARLKDLE", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . :. .. **: :::** .*** :: ** : . **::: ::.. . . : . .: :** ..: :: ::. :* * : *: *. * :: : : : : : *:.: : : .*.**:** . . *:: * ****:* *: : : * . *** * *.: : .* :*:: :* ::.*: : * .:::* :*: :* . .. :. :::. : :: : : . .. . :**::::* ::*:* *:.:*: :.. :: * .::. * : . .:: : *****:. :*:*******.* * * : : * .: : . : .:.: . : : :***** **: .. * . : : :: *: ::* . *:****:*: . : ***:. :: : : : * **: . : : : :*. * :*: :* :.*:*.**:** **: ..::: :: **:*:*:***** *** . :* : : : . : : .::** :: . * ::. . :*:*** :* **: :* :: . * :*******::** .:.:*:** *:** ** * :*::. :: * :*::.**: * : :: **:: : ::* . :* :*:. * ::: : *:.. .: :: * . ** . * * . . . : :: : : * : : :* .:* : .: : * ::. * : :: .:. * :: . : : .. : : ", "identical_positions": 173, "similar_positions": 306, "identity": "9.52%" }, { "cls_id": "homologset.agr.MGI:1859664", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A2ANX3-1", "uniprot_id": "A2ANX3_MOUSE", "id": "A2ANX3-1", "name": "Phospholipid-transporting ATPase", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MMFCNKKKLLEVERVVKANDRDYNEKFQYADNRIHTSKYNVLTFLPINLFEQLQRVANAYFLFLLILQLIPEISSLTWFTTIVPLVLVISMTAVKDATDDYFRHKSDNQVNNRQSKVLI-------------------------------------------------------------------------------------------------------------------NSKLQNEKWMNVKVGDIIKLENNQFVAADLLLLSSSEPHGLCYVETAELDGETNLKVRQALPVTSELGADISSLAEFDGIVRCEAPNNKLDRFSGVLSWKDS------KHALSNQKIILRGCVLRNTSWCFGMVLFAGPDTKLMQNSGKTKFKRTSIDRLMNTLVLWIFGFLVCLGIILAVGSSILESEVGDQFRTPPFWREGE------KSFLFSGFLTFWSYVIILNTLVPISLYVSVEVIRLGHSYFINWDRKMYYASKAMPAEARTTTLNEELGQIEYIFSDKTGTLTQNIMTFKKCSINGRVYAGEVLDDPI----------------QKKEITKEK--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------EATDFSSKSKSEKTLHFFDQSLMESIELGDPKVHEFLRLLALCHTVMSEEN--SAGQLVYQVQSPDEGALVTAARNFGFIFKSRTPETITIEELGTPVTYQLLAFLDFNNIRKRMSVIVRN------PEGRIKLYSKGADTILFEKLHP----SNEDLQSLTSDHLSEFAGEGLRTLAIAYRELDDKYFKMWQKMLEDANSATLERDERISGLYEEIERDLMLLGATAVEDKLQEGVIETITSLSLANIKIWILTGDKQETAINIGYACNVLTDAMDALFVIT-GNTAGEVREELRKAKENLLGQ-----------------------------------------------------------STSFSNGHAVYDNKQRLGLDAGAGEAVTG--------EYALVINGHSLAHALES-DVENDLLELACVCKTVVCCRVTPLQKAQVVELVKKHRNAVTLAIGDGANDVSMIKSAHIGIGISGQEGLQAVLASDYALAQFRYLQRLLLVHGRWSYYRMCKFLCYFFYKNFAFTLVHFWFAFFCGFSAQTVYDQWFITLFNIVYTSLPVLAMGMFDQDINEQNSMDYPQLYEPGQLNLLFNKRRFFICVAHGIYTSLALFFIPYGAFYN--VAAEDGQHIADLQSFAVTVATSLVIVVSIQIALDTSYWTVVNHVFIWGSVATYFSILLAMHSDGVFGIFPRHFPFVGNARHSLSQKFVWLVVLLTAVTSVMPVVVVRFLKMYLYPSLSDQIRR---------WQKAQRKKRPLRSRRPQTRR-SSSRRSGYAFAHQEG----YGELITSGKNMRAK------SPAPASGLEKKLYNNTSWIENLCKKTTDAVSGFSHDKTVKL-------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A1B0GWR9-1", "uniprot_id": "A0A1B0GWR9_RAT", "id": "A0A1B0GWR9-1", "name": "Phospholipid-transporting ATPase", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MMFCNEKKLLEVERVVKANDRDYNEKFQYADNRIHTSKYNILTFLPINLFEQFQRVANAYFLFLLILQLIPEISSLTWFTTIVPLVLVISMTAVKDATDDFFRHKSDNQVNNRQSEVLI-------------------------------------------------------------------------------------------------------------------NSKLQNEKWMNVKVGDIIKLENNQFVAADLLLLSSSEPHGLCYVETAELDGETNLKVRQALPVTSELGADISSLAKFDGIVICEAPNNKLDRFSGVLSWKDS------KHTLSNQKIILRGCVLRNTSWCFGMVLFAGPDTKLMQNSGKTKFKRTSIDRLMNTLVLWIFGFLVCLGIILAVGNSIWESEVGNQFRTSLFWREGE------KSSLFSGFLTFWSYVIILNTLVPISLYVSVEVIRLGHSYFINWDRKMYYAAKAMPAEARTTTLNEELGQIEYIFSDKTGTLTQNIMTFKKCSINGRVYAGEVLDDLD----------------QKKEITKKK--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------EAVDFSGKSKSERTLHFFDHSLMESIELGDPKVHEFLRLLALCHTVMSEED--SAGQLVYQVQSPDEGALVTAARNFGFIFKSRTPETITIEELGTPVTYQLLAFLDFNNIRKRMSVIVRN------PEGQIKLYSKGADTILFEKLHP----SNEDLLSLTSDHLSEFAGEGLRTLAIAYRELDDKYFKMWQKMLEDANSAIAERDERISGLYEEIERDLMLLGATAVEDKLQEGVIETITSLSLANIKIWILTGDKQETAINIGYACNVLTDAMDAVFVIT-GNTAVEVREELRKAKENLLGQ-----------------------------------------------------------NTSFSNGHAVYENKQRLELDSGAGETVTG--------EYALVINGHSLAHALES-DVEKDLLELACVCKTVVCCRVTPLQKAQVVELVKKHRNAVTLAIGDGANDVSMIKSAHIGIGISGQEGLQAVLASDYALAQFRYLQRLLLVHGRWSYYRMCKFLCYFFYKNFAFTLVHFWFAFYCGFSAQTVYDQWFITLFNIVYTSLPVLAMGVFDQDVSEQNSMDCPQLYEPGQLNLLFNKRRFFICVAHGIYTSLILFFIPYGAFYN--VAAEDGQHIADYQSFAVTVATSLVIVVSVQIALDTSYWTVVNHVFIWGSVATYFSILLAMHSDGVFGIFPRQFPFVGNARRSLSQKFVWLVVLLTAVTSVMPVVVFRFLKMHLYPSLSDQIRR---------WQKAQRKERPLRSRRPQTRR-SSSRRSGYAFAHQEG----YGELITSGKNMRAK------SPAPTSGLEKMLYSNTSWIGNLCKKTTDVVSGFSHDKTVKL-------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8TF62-1", "uniprot_id": "AT8B4_HUMAN", "id": "Q8TF62-1", "name": "Probable phospholipid-transporting ATPase IM", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MFCSEKKLREVERIVKANDREYNEKFQYADNRIHTSKYNILTFLPINLFEQFQRVANAYFLCLLILQLIPEISSLTWFTTIVPLVLVITMTAVKDATDDYFRHKSDNQVNNRQSEVLI-------------------------------------------------------------------------------------------------------------------NSKLQNEKWMNVKVGDIIKLENNQFVAADLLLLSSSEPHGLCYVETAELDGETNLKVRHALSVTSELGADISRLAGFDGIVVCEVPNNKLDKFMGILSWKDS------KHSLNNEKIILRGCILRNTSWCFGMVIFAGPDTKLMQNSGKTKFKRTSIDRLMNTLVLWIFGFLICLGIILAIGNSIWESQTGDQFRTFLFWNEGE------KSSVFSGFLTFWSYIIILNTVVPISLYVSVEVIRLGHSYFINWDRKMYYSRKAIPAVARTTTLNEELGQIEYIFSDKTGTLTQNIMTFKRCSINGRIYG-EVHDDLD----------------QKTEITQEK--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------EPVDFSVKSQADREFQFFDHHLMESIKMGDPKVHEFLRLLALCHTVMSEEN--SAGELIYQVQSPDEGALVTAARNFGFIFKSRTPETITIEELGTLVTYQLLAFLDFNNTRKRMSVIVRN------PEGQIKLYSKGADTILFEKLHP----SNEVLLSLTSDHLSEFAGEGLRTLAIAYRDLDDKYFKEWHKMLEDANAATEERDERIAGLYEEIERDLMLLGATAVEDKLQEGVIETVTSLSLANIKIWVLTGDKQETAINIGYACNMLTDDMNDVFVIA-GNNAVEVREELRKAKQNLFGQ-----------------------------------------------------------NRNFSNGHVVCEKKQQLELDSIVEETITG--------DYALIINGHSLAHALES-DVKNDLLELACMCKTVICCRVTPLQKAQVVELVKKYRNAVTLAIGDGANDVSMIKSAHIGVGISGQEGLQAVLASDYSFAQFRYLQRLLLVHGRWSYFRMCKFLCYFFYKNFAFTLVHFWFGFFCGFSAQTVYDQWFITLFNIVYTSLPVLAMGIFDQDVSDQNSVDCPQLYKPGQLNLLFNKRKFFICVLHGIYTSLVLFFIPYGAFYN--VAGEDGQHIADYQSFAVTMATSLVIVVSVQIALDTSYWTFINHVFIWGSIAIYFSILFTMHSNGIFGIFPNQFPFVGNARHSLTQKCIWLVILLTTVASVMPVVAFRFLKVDLYPTLSDQIRR---------WQKAQKKARPPSSRRPRTRR-SSSRRSGYAFAHQEG----YGELITSGKNMRAK------NPPPTSGLEKTHYNSTSWIENLCKKTTDTVSSFSQDKTVKL-------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8N7TEK0-1", "uniprot_id": "A0A8N7TEK0_DANRE", "id": "A0A8N7TEK0-1", "name": "Phospholipid-transporting ATPase", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MDGACFRETLRTRRR--WPGVMAIWKKDVHIEEERHVRANDRDYNERFSYADNRIKTAKYNVFTFLPINLFEQFQRFANAYFLVLLILQLIPEISSLSWFTTIVPLVLVLAITAVKDATDDYFRHKSDQQVNTRQSQVLI-------------------------------------------------------------------------------------------------------------------KGKLQNEKWMNVRVGDVIKLENNQFVAADLLLLSSSEPYGLCYIETAELDGETNLKVRQALTVTSDLGDDVAKLADFNGEVICEPPNNKLDKFIGTLYWKDN------KYPLDNEKMLLRGCVLRNTEWCFGLVIFAGLQTKLMQNCGRTKFKRTSIDKLMNTLVLWIFGFLICMGIILAIGNTIWEQSVGSDFWAYLQWKELT------VNAVFSGFLTFWSYIIILNTVVPISLYVSVEVLRLGHSYFINWDRRMYYSRKDTPAEARTTTLNEELGQVEFIFSDKTGTLTQNIMVFNKCSINGKTYG-DVFDEFG----------------HKVDITEKT--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------PCVDFSFNPLMDRKFRFHDSSLVEAIKLEEPLVQEFFRLLALCHTVMPEER--NEGELVYQAQSPDEGALVTAARNFGFVFRSRTPETITLYEMGQAVTYQLLAILDFNNVRKRMSVIVRN------PKGQLKLYSKGADTILFDRLDP----SNEELMFTTSEHLNEFAGEGLRTLALAYKDLDEDVFDEWTKKLLFASTALDNREEKLGALYEEIEQGMMLLGATAIEDKLQEGVPETIACLTLANIKIWVLTGDKLETAMNIGYSCNMLRDDMNEVFIIS-GHTMLEVQQELRTAKERIMGP-----------------------------------------------------------SKDKFSSGLDMEKTELYSVDSVFEETIIA--------EYALIINGHSLAHALEA-ELEQILVDVACLCKSVICCRVTPLQKALVVELIKRHKRAVTLAIGDGANDVSMIKTAHIGVGISGQEGMQAVLASDYSFAQFRYLQRLLLVHGRWSYHRMCNFLCYFFYKNFAFTLVHFWYGFLCGFSAQTVYDQWFITLFNIVYTSLPVLAMGLFDQDVNEQYSLRYPNLYRPGQLNQLFNKRKFFTCTLQGVYTSFILFFIPYGAFMP--AVRDDGAQISDQQAFAVTIATSLVIVVSVQIGLDTNYWTAVNHFFIWGSLAVYFAILFAMNSNGIFTIFPNQFPFIGSARNSLNQKIVWLVILLNTVVCIMPMLAVRFIKTDLYPTHTDKVRL---------LQQATRRQRPQEQNLRRVRR-TSSRRSAYAFSHQQG----YGELITSGKNMKV----------PTSSTSTYPLSSPSRAPGEKGTTSANSRPSEHKQEVTVEDLEAR-------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VGD4-1", "uniprot_id": "Q9VGD4_DROME", "id": "Q9VGD4-1", "name": "Phospholipid-transporting ATPase", "aln": "--------------------MIGGRRCSEAARRLRRRPDTLELSVLGGQPIETELQEDNERTPTKGAGNVDEPGIEAPEASCSAPSKRTRWFQFARSSKNRRKRLHCNEDEDVKQPERRNSDLEGSPRACLAQPEGMNIGSSTQTIATPLMIGDSFYSLAPGGGNPPPNKSDDQELYKQRDPSVTSESKSVPSLRR--LSQIRRRRSSYYFSENERRIRANDKEFNAQFKYHNNYIKTSKYSLFTFLPFNLLEQFQRLANFYFLCLLVLQLIPAISSLTPVTTAIPLIGVLTLTAVKDAYDDIQRHISDSQVNNRKSKTLR-------------------------------------------------------------------------------------------------------------------NGKLVEAKWSEVQVGDVIRLDNNQFVAADTLLLSTSEPNGLCFIETAELDGETNLKAKQCLTETIELGDRHDSLWNFNGEIICERPNNLLNKFDGTLIWRGQ------RFALDNEKILLRGCVLRNTQWCYGVVVFAGVDTKLMQNSGKTQFKSTGVDRLLNFIIIGIVLFLVSICALFAIGCAIWEGLIGQHFQLYLPWEHIIPKDYIPTGATVIGLLVFFSYAIVLNTVVPISLYVSVEVIRFVQSFLINWDEEMYYPTTNTYAKARTTTLNEELGQIQYIFSDKTGTLTQNIMTFNKCSINGRSYGDVIDLRTG----------------ELVEITEQQTIFQNSNTNNRPSPLSGAIVAPPAAPPPIILVHKAEVHAKKTSMVVTSSGEAQVLPDRPRSDIERSAPPMDASEKRPGLKHVRYSAPSRSQDADAGRLSPRLDGSGGLSPPVGNEERRISGGFKRSGAGCMQRQLSRTSSCDKVKILHDSQQTETHNMHHSSHNRKRLVKIRFKKAPSTATLGVVISQLEHHLDEEPQSTSTLSTTKHHHHRSKAFATNWSSSPHRVHALQSVDFSANPHHESDFRWYDRTLLDAVRSDEEHSHVFFRLLALCHTVMAET---VDGKLEYQAQSPDEAALVSAARNFGFVFRTRTPNSITIEVMGQTEEYELLNILDFNNVRKRMSVILRR------GDS-MVLYCKGADNVIYDRLHG----GQEDLKARTQDHLNKFAGEGLRTLALAERRLTEQYYNDWRSRQQEAALSMDSREQKLNAIYEEIESEMQLVGVTAIEDKLQDGVPKSIANLQNAGIKIWVLTGDKQETAINIGYSCQLLTDELADVFIVD-GNSVEEVEKQLRQFKESIKIYNRFRPGGFDPFDRLNSDSNMDPLSVTMTQTSAFMQETNLPPTPPPPPAISVVTFRWDEKNKDNKGGPDSAECNNLFGDEKGSEDGGTASIVVDENTGFALVVNGHSLVHCLSP-ELENKFLDIASQCKAVICCRVTPLQKALVVELIKRAKNAVTLAIGDGANDVSMIKAAHIGVGISGQEGLQAVLSSDYSIAQFRYLERLLLVHGRWSYYRMCKFLRYFFYKNFAFTLCHCWYSLFCGFSAQTVFDPMFISVYNLFYTSLPVLALGVFEQDVSDKNSLEFPRLYTPGLKSELFNIREFIYSVLHGAFTSLVLFLIPYGVYKD--GVSANGFVVSDHMTLGAVVATILIVDNTAQISLYTSYWTVVNHVTIWGSLVWYFVLDYFYN-------YVIGGPYVGSLTQAMKDLTFWVTMLITVMALVAPVLAYKFYLLDVHPSLSDKIRQKS-------LKKIHSRASSDVRRTASSRRGRRSVRSGYAFAHQEG----FGRLITSGKIMHKLPQDFAFPLGLGTKKTQVLHNNLNSADGPNSKGNNVTGHHMVNNNTNMRHNQNQNHSSMADITADGRGNGGDDGRGSGGSDDMSPRAPCQDLDTINL", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q12675-1", "uniprot_id": "ATC4_YEAST", "id": "Q12675-1", "name": "Phospholipid-transporting ATPase DNF2", "aln": "MSSPSKPTSPFVDDIEHESGSASNGLSSMSPFDDSFQFEKPSSAHGNIEVAKTGGSVLKRQSKPMKDISTPDLSKVTFDGIDDYSNDNDINDDDELNGKKTEIHEHENEVDDDLHSFQATPMPNTGG--FEDVELDNNEGSNNDSQADHKLKRVRFGTRRNKSGRIDINRSKTLKWAKKNFHNAIDEFSTKEDSLENSALQNRSDELRTVYYNLPLPEDMLDEDGLPLAVYPRNKIRTTKYTPLTFFPKNILFQFHNFANIYFLILLILGAFQIFGVTNPGFASVPLIVIVIITAIKDGIEDSRRTVLDLEVNNTRTHILSGVKNENVAVDNVSLWRRFKKANTRALIKIFEYFSENLTAAGREKKLQKKREELRRKRNSRSFGPRGSLDSIGSYRMSADFGRPSLDYENLNQTMSQANRYNDGENLVDRTLQPNPECRFAKDYWKNVKVGDIVRVHNNDEIPADMILLSTSDVDGACYVETKNLDGETNLKVRQSLKCSKIIKSSRD-ITRTKFWVESEGPHANLYSYQGNFKWQDTQNGNIRNEPVNINNLLLRGCTLRNTKWAMGMVIFTGDDTKIMINAGVTPTKKSRISRELNFSVILNFVLLFILCFTAGIVNGVYYKQKPRSRDYFEFGTIGG-------SASTNGFVSFWVAVILYQSLVPISLYISVEIIKTAQAIFIYTDVLLYNAKLDYPCTPKSWNISDDLGQIEYIFSDKTGTLTQNVMEFKKCTINGVSYGRAYTEALAGLRKRQGVDVESEGRREKEEIAKDRETMIDELRSMS---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------DNTQFCPEDLTFVSKEIVEDLKGSSGDHQQKCCEHFLLALALCHSVLVEPNKDDPKKLDIKAQSPDESALVSTARQLGYSFVGSSKSGLIVEIQGVQKEFQVLNVLEFNSSRKRMSCIIKIPGSTPKDEPKALLICKGADSVIYSRLDR--TQNDATLLEKTALHLEEYATEGLRTLCLAQRELTWSEYERWVKTYDVAAASVTNREEELDKVTDVIERELILLGGTAIEDRLQDGVPDSIALLAEAGIKLWVLTGDKVETAINIGFSCNVLNNDMELLVVKASGEDVEEFGSDPIQVVNNLVTK-------------------------------------------------------------YLREKFGMSGSEEELKEAKREHGLPQG--------NFAVIIDGDALKVALNGEEMRRKFLLLCKNCKAVLCCRVSPAQKAAVVKLVKKTLDVMTLAIGDGSNDVAMIQSADVGVGIAGEEGRQAVMCSDYAIGQFRYVTRLVLVHGKWCYKRLAEMIPQFFYKNVIFTLSLFWYGIYNNFDGSYLFEYTYLTFYNLAFTSVPVILLAVLDQDVSDTVSMLVPQLYRVGILRKEWNQTKFLWYMLDGVYQSVICFFFPYLAYHKNMVVTENGLGLDHRYFVGVFVTAIAVTSCNFYVFMEQYRWDWFCGLFICLSLAVFYGWTGIWTS------SSSSNEFYKGAARVFAQPAYWAVLFVGVLFCLLPRFTIDCIRKIFYPKDIEIVREMWLRGDFDLYPQGYDPTDPSRPRINEIRPLTD-FKEPISLDTHFDGVSHSQETIVTEEIPMSILNGEQGSRKGYRVSTTLER--RDQLSPVTTTNNLPRRSMASARGNKLRTSLDRTREEMLANHQLDTRYSVERARASLDLPGINHAETLLSQRSRDR", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P32660-1", "uniprot_id": "ATC5_YEAST", "id": "P32660-1", "name": "Phospholipid-transporting ATPase DNF1", "aln": "MSG----------------TFHGDGHAPMSPFEDTFQFEDNSSNE-DTHIAPT----------HFDDGATSNKYSRPQVSFNDETPKNKREDAEEFT--------FNDDTEYDNHSFQPTPKLNNGSGTFDDVELDNDSGEPHTN--YDGMKRFRMGTKRNKKGNPIMGRSKTLKWARKNIPNPFEDFTK--DDIDPGAIN-RAQELRTVYYNMPLPKDMIDEEGNPIMQYPRNKIRTTKYTPLTFLPKNILFQFHNFANVYFLVLIILGAFQIFGVTNPGLSAVPLVVIVIITAIKDAIEDSRRTVLDLEVNNTKTHILEGVENENVSTDNISLWRRFKKANSRLLFKFIQYCKEHLTEEGKKKRMQRKRHELRVQKTVGTSGPRSSLDSIDSYRVSADYGRPSLDYDNLEQGAGEAN-------IVDRSLPPRTDCKFAKNYWKGVKVGDIVRIHNNDEIPADIILLSTSDTDGACYVETKNLDGETNLKVRQSLKCTNTIRTSKD-IARTKFWIESEGPHSNLYTYQGNMKWRNLADGEIRNEPITINNVLLRGCTLRNTKWAMGVVMFTGGDTKIMLNSGITPTKKSRISRELNFSVVINFVLLFILCFVSGIANGVYYDKKGRSRFSYEFGTIAG-------SAATNGFVSFWVAVILYQSLVPISLYISVEIIKTAQAAFIYGDVLLYNAKLDYPCTPKSWNISDDLGQVEYIFSDKTGTLTQNVMEFKKCTINGVSYGRAYTEALAGLRKRQGIDVETEGRREKAEIAKDRDTMIDELRALS---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------GNSQFYPEEVTFVSKEFVRDLKGASGEVQQRCCEHFMLALALCHSVLVEANPDNPKKLDLKAQSPDEAALVATARDVGFSFVGKTKKGLIIEMQGIQKEFEILNILEFNSSRKRMSCIVKIPGLNPGDEPRALLICKGADSIIYSRLSRQSGSNSEAILEKTALHLEQYATEGLRTLCIAQRELSWSEYEKWNEKYDIAAASLANREDELEVVADSIERELILLGGTAIEDRLQDGVPDCIELLAEAGIKLWVLTGDKVETAINIGFSCNLLNNEMELLVIKTTGDDVKEFGSEPSEIVDALLSK-------------------------------------------------------------YLKEYFNLTGSEEEIFEAKKDHEFPKG--------NYAIVIDGDALKLALYGEDIRRKFLLLCKNCRAVLCCRVSPSQKAAVVKLVKDSLDVMTLAIGDGSNDVAMIQSADVGIGIAGEEGRQAVMCSDYAIGQFRYLARLVLVHGRWSYKRLAEMIPEFFYKNMIFALALFWYGIYNDFDGSYLYEYTYMMFYNLAFTSLPVIFLGILDQDVNDTISLVVPQLYRVGILRKEWNQRKFLWYMLDGLYQSIICFFFPYLVYHKNMIVTSNGLGLDHRYFVGVYVTTIAVISCNTYVLLHQYRWDWFSGLFIALSCLVVFAWTGIWSS------AIASREFFKAAARIYGAPSFWAVFFVAVLFCLLPRFTYDSFQKFFYPTDVEIVREMWQHGHFDHYPPGYDPTDPNRPKVTKAGQHGEKIIEGIALSDNLGGSNYSRDSVVTEEIPMTFMHGEDGSPSGYQKQETWMTSPKETQDLLQSPQFQQAQTFGRGPSTNVRSSLDRTREQMIATNQLDNRYSVERARTSLDLPGVTNAASLIGTQQNN-", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : *.: * * *:*:**. :**:* *:: *::..** *** *::* : :. . : :**: :: :**:**. :* * * :**. ::. * . :: : * *:***::::.**: :.** :***:*: * *::** :********.::.* : : : . : .* *: * : * : *:. . .: ::::**** ****.*. *:*:*:* :**:* *.* * * : :.: :* :: . :*. : .: : . *:: *: *: :::******:***::: :: :* * :* . . .:: .:.::***:::************:* *::*:*** *. . :*::. :* : . : : . *: *****:*: * :* :.*****.***::**:.*: * : . : : * :::* .*:**. ***** *:: . * .****.:::.:* .. : * **.::* ******.:* : * . :. * . * : .*::.: : : ** : *:* **:**:**:** . : * *.**:*:***** ***:***::*::* : : :.: *. *. .: : : : . :*::::*.:* .* ::.. :: :. *::*:****:* *** **:*:* .:*******:***:**::*.:*:**:*:** ***:.***::.****: **:****:*.* *:.::: *****. *:* *:.: .*... ::: :: .:*: :**:**: :.:::**:.: *: *.** * :* .*: .* : *. *::** .: . :* : . ... ::: : . : : * . . * * : : . * ..:: .: : * .. .:*. : :* . . . :: : . :.: : . .: ", "identical_positions": 300, "similar_positions": 357, "identity": "15.62%" }, { "cls_id": "homologset.agr.MGI:1859665", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q148W0-1", "uniprot_id": "AT8B1_MOUSE", "id": "Q148W0-1", "name": "Phospholipid-transporting ATPase IC", "aln": "------------------------------MSTER--DSETTFDEESQPNDEVVPYSD-------------DETEDELEDQGSTVEPEQNRVNR-------------------EAEKKRETFRKDCTWQ--------------------------------------------VKANDRKFHEQ------------PHFMNTKFFCIKES------------------------KYASNAIKTYKYNGFTFLPMNLFEQFKRAANFYFLILLILQAIPQISTLAWYTTLVPLLLVLGITAIKDLVDDVARHKMDKEINNRTCEVIK-------------------------------------------------------------------------------------------------------------------DGRFKIIKWKDIQVGDVIRLKKNDFIPADILLLSSSEPNSLCYVETAELDGETNLKFKMALEITDQYLQIEDNLATFDGFIECEEPNNRLDKFTGTLFWKNQ------SFPLDADKILLRGCVIRNTDVCHGLVIFAGADTKIMKNSGKTRFKRTKIDYLMNYMVYTIFIVLILVSAGLAIGHAYWEAQVGNY-----SWYLYDGENATPS---YRGFLNFWGYIIVLNTMVPISLYVSVEVIRLGQSHFINWDLQMYYAEKDTPAKARTTTLNEQLGQIHYIFSDKTGTLTQNIMTFKKCCINGTIYG--------------------------------------------------------------------------------------------------------------------------------------------------------------------------DHRDASQHSHSK----------------------------------------------------------------IELVDFSWN-TFADGKLAFYDHYLIEQIQS----GKEPEVRQFFFLLSICHTVMVDRIDG---QINYQAASPDEGALVNAARNFGFAFLARTQNTITVSELGSERTYNVLAILDFNSDRKRMSIIVRTPEG------SIRLYCKGADTVIYERLHR-----MNPTKQETQDALDIFASETLRTLCLCYKEIEEKEFTEWNNKFMAASVASSNRDEALDKVYEEIEKDLILLGATAIEDKLQDGVPETISKLAKADIKIWVLTGDKKETAENIGFACELLTEDTTICYGEDIN--SLLHTRMENQRNRGGVSAKFAPPVYEPFFPPGENR---ALIITGSWLNEILLEKKTKRS-------KILKLKFPRTEEERRMRSQ---SRRRLEEKK--------------------------------EQRQKNFVDLACECSAVICCRVTPKQKAMVVDLVKRYKKAITLAIGDGANDVNMIKTAHIGVGISGQEGMQAVMSSDYSFAQFRYLQRLLLVHGRWSYIRMCKFLRYFFYKNFAFTLVHFWYSFFNGYSAQTAYEDWFITLYNVLYSSLPVLLMGLLDQDVSDKLSLRFPGLYVVGQRDLLFNYKRFFVSLLHGVLTSMVLFFIPLGAYLQ--TVGQDGEAPSDYQSFAVTVASALVITVNFQIGLDTSYWTFVNAFSIFGSIALYFGIMFDFHSAGIHVLFPSAFQFTGTASNALRQPYIWLTIILTVAVCLLPVVAIRFLSMTIWPSESDKIQ-KHRKRLKAEEQ------WKRRQSVFRRGVSSRRSAYAFSHQRGYADLISSGRSIRKKRSPLDAIIADGTAEYRRTVES---------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D4AA47-1", "uniprot_id": "AT8B1_RAT", "id": "D4AA47-1", "name": "Phospholipid-transporting ATPase IC", "aln": "------------------------------MNTER--DSETTFDEDSQPNDEVVPYSD-------------DETEDELEDQGPAVEPEQNRVNR-------------------EVEKKKETFRKDCTWQ--------------------------------------------VKANDRKFHEQ------------PHFMNTKFFCIKES------------------------KYASNAIKTYKYNALTFLPMNLFEQFKRAANFYFLILLILQAIPQISTLAWYTTLVPLLLVLGITAIKDLVDDVARHKMDKEINNRTCEVIK-------------------------------------------------------------------------------------------------------------------DGRFKIIKWKDIQVGDVIRLKKNDFIPADILLLSSSEPNSLCYVETAELDGETNLKFKMALEITDQYLQIEDNLATFDGFIECEEPNNRLDKFTGTLFWRNQ------SFPLDADKILLRGCVIRNTDVCHGLVIFAGADTKIMKNSGKTRFKRTKIDYLMNYMVYTIIIVLILVSAGLAIGHAYWEAQIGNY-----SWYLYDGENATPS---YRGFLNFWGYIIVLNTMVPISLYVSVEVIRLGQSHFINWDLQMYYAEKDTPAKSRTTTLNEQLGQIHYIFSDKTGTLTQNIMTFKKCCINGTIYG--------------------------------------------------------------------------------------------------------------------------------------------------------------------------DHRDASQHSHSK----------------------------------------------------------------IELVDFSWN-EFADGKLAFYDHYLIEQIQS----GKEPEVRQFFFLLSICHTVMVDRIDG---QINYQAASPDEGALVNAARNFGFAFLARTQNTITVSELGTERTYSVLAILDFNSDRKRMSIIVRTPEG------SIRLYCKGADTVIYERLHR-----MNPMKQETQDALDIFASETLRTLCLCYKEIEEKEFAEWNKKFMAASVASSNRDEALDKVYEEIERDLILLGATAIEDKLQDGVPETISKLAKADIKIWVLTGDKKETAENIGFACELLTEDTTICYGEDIN--SLLHTRMENQRNRGGVSAKFAPPAYEPFFPPGENR---ALIITGSWLNEILLEKKTKRS-------KILKLKFPRTEEERRMRSQ---SRRRLEEKK--------------------------------EQRQKNFVDLACECSAVICCRVTPKQKAMVVDLVKRYKKAITLAIGDGANDVNMIKTAHIGVGISGQEGMQAVMSSDYSFAQFRYLQRLLLVHGRWSYIRMCKFLRYFFYKNFAFTLVHFWYSFFNGYSAQTAYEDWFITLYNVLYSSLPVLLMGLLDQDVSDKLSLRFPGLYVVGQRDLLFNYKKFFVSLLHGVLTSMVLFFIPFGAYLQ--TVGQDGEAPSDYQSFAVTMASALVITVNFQIGLDTSYWTFVNAFSIFGSIALYFGIMFDFHSAGIHVLFPSAFQFTGTASNALRQPYIWLTIILTVAVCLLPVVAIRFLSMTIWPSESDKIQ-KHRKRLKAEEQ------WKRRQSVFRRGASSRRSAYAFSHQRGYADLISSGRSIRKKRSPLDAIIADGTAEYRRTVES---------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O43520-1", "uniprot_id": "AT8B1_HUMAN", "id": "O43520-1", "name": "Phospholipid-transporting ATPase IC", "aln": "------------------------------MSTER--DSETTFDEDSQPNDEVVPYSD-------------DETEDELDDQGSAVEPEQNRVNR-------------------EAEENREPFRKECTWQ--------------------------------------------VKANDRKYHEQ------------PHFMNTKFLCIKES------------------------KYANNAIKTYKYNAFTFIPMNLFEQFKRAANLYFLALLILQAVPQISTLAWYTTLVPLLVVLGVTAIKDLVDDVARHKMDKEINNRTCEVIK-------------------------------------------------------------------------------------------------------------------DGRFKVAKWKEIQVGDVIRLKKNDFVPADILLLSSSEPNSLCYVETAELDGETNLKFKMSLEITDQYLQREDTLATFDGFIECEEPNNRLDKFTGTLFWRNT------SFPLDADKILLRGCVIRNTDFCHGLVIFAGADTKIMKNSGKTRFKRTKIDYLMNYMVYTIFVVLILLSAGLAIGHAYWEAQVGNS-----SWYLYDGEDDTPS---YRGFLIFWGYIIVLNTMVPISLYVSVEVIRLGQSHFINWDLQMYYAEKDTPAKARTTTLNEQLGQIHYIFSDKTGTLTQNIMTFKKCCINGQIYG--------------------------------------------------------------------------------------------------------------------------------------------------------------------------DHRDASQHNHNK----------------------------------------------------------------IEQVDFSWN-TYADGKLAFYDHYLIEQIQS----GKEPEVRQFFFLLAVCHTVMVDRTDG---QLNYQAASPDEGALVNAARNFGFAFLARTQNTITISELGTERTYNVLAILDFNSDRKRMSIIVRTPEG------NIKLYCKGADTVIYERLHR-----MNPTKQETQDALDIFANETLRTLCLCYKEIEEKEFTEWNKKFMAASVASTNRDEALDKVYEEIEKDLILLGATAIEDKLQDGVPETISKLAKADIKIWVLTGDKKETAENIGFACELLTEDTTICYGEDIN--SLLHARMENQRNRGGVYAKFAPPVQESFFPPGGNR---ALIITGSWLNEILLEKKTKRN-------KILKLKFPRTEEERRMRTQ---SKRRLEAKK--------------------------------EQRQKNFVDLACECSAVICCRVTPKQKAMVVDLVKRYKKAITLAIGDGANDVNMIKTAHIGVGISGQEGMQAVMSSDYSFAQFRYLQRLLLVHGRWSYIRMCKFLRYFFYKNFAFTLVHFWYSFFNGYSAQTAYEDWFITLYNVLYTSLPVLLMGLLDQDVSDKLSLRFPGLYIVGQRDLLFNYKRFFVSLLHGVLTSMILFFIPLGAYLQ--TVGQDGEAPSDYQSFAVTIASALVITVNFQIGLDTSYWTFVNAFSIFGSIALYFGIMFDFHSAGIHVLFPSAFQFTGTASNALRQPYIWLTIILAVAVCLLPVVAIRFLSMTIWPSESDKIQ-KHRKRLKAEEQ------WQRRQQVFRRGVSTRRSAYAFSHQRGYADLISSGRSIRKKRSPLDAIVADGTAEYRRTGDS---------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "E7FFK0-1", "uniprot_id": "E7FFK0_DANRE", "id": "E7FFK0-1", "name": "Phospholipid-transporting ATPase", "aln": "------------------------------MNSRSRADSQGSLDE---PDDEVMPYSD-------------DETDAELED-----ELDQSVDQL-------------------PEPETRPAPAVEAGWS--------------------------------------------VRANDREYCKR------------PEFQKKVFLCIKKS------------------------RYSGNAIKTYKYNVLTFLPLNLYEQFKRAANLYFLCLLVLQIIPQISTLPWYTTLVPLVLVLGITAIKDLVDDLARHRMDKEINNRKCDVLL-------------------------------------------------------------------------------------------------------------------NGRFVETRWMNLQVGDVVRLHKNDFIPADIMLLSTSNPNSLCYVETAELDGETNLKFKMGLKVTDERLQEEQQLSQFNALVMCEEPNNRLDKFVGTMIWESQ------SYALDLDNMLLRGCKVRNTDICHGLVIFAGNDTKIMRNGGKTRFKRTRIDKLMNYMVYTIFVLLVLLCAGLAIGHTYWYESIGSK-----AWYLIDGLDYTSS---YRGFLSFWGYIIILNTMVPISLYVSVEVIRLGQSKFINWDLQMYYADKDTPAKSRTTTLNEQLGQIEYIFSDKTGTLTQNIMAFKKCTISGRTYG--------------------------------------------------------------------------------------------------------------------------------------------------------------------------EPTTADGVSLDR----------------------------------------------------------------GKPVDFSWN-KYADRKFQFEDHFLISCIRS----KKDPQVLEFFKLLSLCHTVMVEEKEG---ELVYQAASPDEGALVTAARNFGFVFLSRTQDTITIQEMDKPQTYTMLALLDFNSDRKRMSIILKFPDG------RIRLYCKGADTVIYQRLSP-----QSKNKENTQEALDIFANETLRTLCLCYKDISQEEFDRWSRKHQTAAVSMVDRERELDEVYEEIEKDLLLIGATAIEDKLQDGVPETIAKLAKADIKIWVLTGDKKETAENIGYSCQLLTDDMKIHYGEDVN--VQLRNRQTQRRTDPQSRNKKQ---KESFFNEPGKN---ALIITGGWLNEILYEKKKKRRR-----LRLKKLRLRQNNQQSSSSTAPDSSQPVDDWEK--------------------------------EKRQEDFVDMACECSAVICCRVTPKQKANVVSLVKKYKKAVTLSIGDGANDVNMIKTADIGVGISGQEGMQAVMSSDYAFAQFCFLQRLLLVHGRWSYIRMCKFLRYFFYKNFAFTLVHFWFSFFNGFSAQTAYEDWFITLYNVCYSSLPVLLVGLLDQDVNDKLSLRFPKLYLPGQQGALFNYRNFFISLFHGIFTSLMIFFIPYGAFLQ--TMGQDGEAPSDYQSFAVVAASSLIITVNLQISLNTSYWTFVNFFAVLGSIALYFGIMFDIHSAGIHVIFPNTFTFTGAASNALRQPYLWLTIILTVGVCLLPVICIQFLYQTIYPSVGDKVQ-RNRKKYELEDEE---DERKKRKPTFQRGGRSRRSAYAFSHSRGYADLIASGRSIRQ-RPRVRPELRDSIREVPHAENI---------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VGD4-1", "uniprot_id": "Q9VGD4_DROME", "id": "Q9VGD4-1", "name": "Phospholipid-transporting ATPase", "aln": "MIGGRRCSEAARRLRRRPDTLELSVLGGQPIETELQEDNERTPTKGAGNVDEPGIEAP-------------EASCSAPSKRTRWFQFARSSKNRRKRL------------HCNEDEDVKQPERRNSDLEGSPRACLAQPEGMNIGSSTQTIATPLMIGDSFYSLAPGGGNPPPNKSDDQELYKQRDPSVTSESKSVPSLRRLSQIRRRRSSYYFSEN--ERRIRANDKEFNAQFKYHNNYIKTSKYSLFTFLPFNLLEQFQRLANFYFLCLLVLQLIPAISSLTPVTTAIPLIGVLTLTAVKDAYDDIQRHISDSQVNNRKSKTLR-------------------------------------------------------------------------------------------------------------------NGKLVEAKWSEVQVGDVIRLDNNQFVAADTLLLSTSEPNGLCFIETAELDGETNLKAKQCLTETIELGDRHDSLWNFNGEIICERPNNLLNKFDGTLIWRGQ------RFALDNEKILLRGCVLRNTQWCYGVVVFAGVDTKLMQNSGKTQFKSTGVDRLLNFIIIGIVLFLVSICALFAIGCAIWEGLIGQHFQLYLPWEHIIPKDYIPTGATVIGLLVFFSYAIVLNTVVPISLYVSVEVIRFVQSFLINWDEEMYYPTTNTYAKARTTTLNEELGQIQYIFSDKTGTLTQNIMTFNKCSINGRSYGDVIDLRTGELVEITEQQTIFQNSNTNNRPSPLSGAIVAPPAAPPPIILVHKAEVHAKKTSMVVTSSGEAQVLPDRPRSDIERSAPPMDASEKRPGLKHVRYSAPSRSQDADAGRLSPRLDGSGGLSPPVGNEERRISGGFKRSGAGCMQRQLSRTSSCDKVKILHDSQQTETHNMHHSSHNRKRLVKIRFKKAPSTATLGVVISQLEHHLDEEPQSTSTLSTTKHHHHRSKAFATNWSSSPHRVHALQSVDFSAN-PHHESDFRWYDRTLLDAVRS----DEE-HSHVFFRLLALCHTVMAETVDG---KLEYQAQSPDEAALVSAARNFGFVFRTRTPNSITIEVMGQTEEYELLNILDFNNVRKRMSVILRRGD-------SMVLYCKGADNVIYDRLHGG----QEDLKARTQDHLNKFAGEGLRTLALAERRLTEQYYNDWRSRQQEAALSMDSREQKLNAIYEEIESEMQLVGVTAIEDKLQDGVPKSIANLQNAGIKIWVLTGDKQETAINIGYSCQLLTDELADVFIVDGNSVEEVEKQLRQFKESIKIYNRFRPGGFDPFDRLNSDSNMDPLSVTMTQTSAFMQETNLPPTPPPPPAISVVTFRWDEKNKDNKGGPDSAECNNLFGDEKGSEDGGTASIVVDENTGFALVVNGHSLVHCLSPELENKFLDIASQCKAVICCRVTPLQKALVVELIKRAKNAVTLAIGDGANDVSMIKAAHIGVGISGQEGLQAVLSSDYSIAQFRYLERLLLVHGRWSYYRMCKFLRYFFYKNFAFTLCHCWYSLFCGFSAQTVFDPMFISVYNLFYTSLPVLALGVFEQDVSDKNSLEFPRLYTPGLKSELFNIREFIYSVLHGAFTSLVLFLIPYGVYKD--GVSANGFVVSDHMTLGAVVATILIVDNTAQISLYTSYWTVVNHVTIWGSLVWYFVLDYFYN-------YVIGGPYVGSLTQAMKDLTFWVTMLITVMALVAPVLAYKFYLLDVHPSLSDKIRQKSLKKIHSRASS-----DVRRTASSRRGRRSVRSGYAFAHQEGFGRLITSGKIMHKLPQDFAFPLGLGTKKTQVLHNNLNSADGPNSKGNNVTGHHMVNN------NTNMRHNQNQNHSSMADITADGRGNGGDDGRGSGGSDDMSPRAPCQDLDTINL", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q12675-1", "uniprot_id": "ATC4_YEAST", "id": "Q12675-1", "name": "Phospholipid-transporting ATPase DNF2", "aln": "-----MSSPSKPTSPFVDDIEHESGSASNGLSSMSPFDDSFQFEKPSSAHGNIEVAKTGGSVLKRQSKPMKDISTPDLSKVTFDGIDDYSNDNDINDDDELNGKKTEIHEHENEVDDDLHSFQATPMPNTGG--FEDVELDNNEGSNNDSQADHKLKRVRFGTRRNKSGRIDINRSKTLKWAKKNFHNAIDEFSTKEDSLENSALQNRSDELRTVYYNLPLPEDMLDEDGLPLAVYPRNKIRTTKYTPLTFFPKNILFQFHNFANIYFLILLILGAFQIFGVTNPGFASVPLIVIVIITAIKDGIEDSRRTVLDLEVNNTRTHILSGVKNENVAVDNVSLWRRFKKANTRALIKIFEYFSENLTAAGREKKLQKKREELRRKRNSRSFGPRGSLDSIGSYRMSADFGRPSLDYENLNQTMSQANRYNDGENLVDRTLQPNPECRFAKDYWKNVKVGDIVRVHNNDEIPADMILLSTSDVDGACYVETKNLDGETNLKVRQSLKCSKIIKSSRD-ITRTKFWVESEGPHANLYSYQGNFKWQDTQNGNIRNEPVNINNLLLRGCTLRNTKWAMGMVIFTGDDTKIMINAGVTPTKKSRISRELNFSVILNFVLLFILCFTAGIVNGVYYKQKPRS-------RDYFEFGTIGGSASTNGFVSFWVAVILYQSLVPISLYISVEIIKTAQAIFIYTDVLLYNAKLDYPCTPKSWNISDDLGQIEYIFSDKTGTLTQNVMEFKKCTINGVSYG-----------------------------------------------------------------------------------------------------------------------------------------------------RAYTEALAGLRKRQGVDVESEGRREKEEIAKDRE------------------------------------------------------------TMIDELRSMSDNTQFCPEDLTFVSKEIVEDLKGSSGDHQQKCCEHFLLALALCHSVLVEPNKDDPKKLDIKAQSPDESALVSTARQLGYSFVGSSKSGLIVEIQGVQKEFQVLNVLEFNSSRKRMSCIIKIPGSTPKDEPKALLICKGADSVIYSRLDR--TQNDATLLEKTALHLEEYATEGLRTLCLAQRELTWSEYERWVKTYDVAAASVTNREEELDKVTDVIERELILLGGTAIEDRLQDGVPDSIALLAEAGIKLWVLTGDKVETAINIGFSCNVLNNDMELLVVKASG-----EDVEEFGSDPIQVVNNLVTKYLREKFGMSGSE---------EELKEAKREHGLPQG----------NFAVIIDGDALKVALNG-------------------------------------------EEMRRKFLLLCKNCKAVLCCRVSPAQKAAVVKLVKKTLDVMTLAIGDGSNDVAMIQSADVGVGIAGEEGRQAVMCSDYAIGQFRYVTRLVLVHGKWCYKRLAEMIPQFFYKNVIFTLSLFWYGIYNNFDGSYLFEYTYLTFYNLAFTSVPVILLAVLDQDVSDTVSMLVPQLYRVGILRKEWNQTKFLWYMLDGVYQSVICFFFPYLAYHKNMVVTENGLGLDHRYFVGVFVTAIAVTSCNFYVFMEQYRWDWFCGLFICLSLAVFYGWTGIWTSS------SSSNEFYKGAARVFAQPAYWAVLFVGVLFCLLPRFTIDCIRKIFYPKDIEIVREMWLRGDFDLYPQGYDPTDPSRPRINEIRPLTD-FKEPISLDTHFDGVSHSQETIVTEEIPMSILNGEQGSRKGYRVSTTLER--RDQLSPVTTTNNLPRRSMASARGNKLRTSLDRTREEMLANHQLDTRYSVERARASLDLPGINHAETLLSQRSRDR", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P32660-1", "uniprot_id": "ATC5_YEAST", "id": "P32660-1", "name": "Phospholipid-transporting ATPase DNF1", "aln": "-----MSG----------------TFHGDGHAPMSPFEDTFQFEDNSSNE-DTHIAPT----------HFDDGATSNKYSRPQVSFNDETPKNKREDAEEFT--------FNDDTEYDNHSFQPTPKLNNGSGTFDDVELDNDSGEPHTN--YDGMKRFRMGTKRNKKGNPIMGRSKTLKWARKNIPNPFEDFTK--DDIDPGAIN-RAQELRTVYYNMPLPKDMIDEEGNPIMQYPRNKIRTTKYTPLTFLPKNILFQFHNFANVYFLVLIILGAFQIFGVTNPGLSAVPLVVIVIITAIKDAIEDSRRTVLDLEVNNTKTHILEGVENENVSTDNISLWRRFKKANSRLLFKFIQYCKEHLTEEGKKKRMQRKRHELRVQKTVGTSGPRSSLDSIDSYRVSADYGRPSLDYDNLEQGAGEAN-------IVDRSLPPRTDCKFAKNYWKGVKVGDIVRIHNNDEIPADIILLSTSDTDGACYVETKNLDGETNLKVRQSLKCTNTIRTSKD-IARTKFWIESEGPHSNLYTYQGNMKWRNLADGEIRNEPITINNVLLRGCTLRNTKWAMGVVMFTGGDTKIMLNSGITPTKKSRISRELNFSVVINFVLLFILCFVSGIANGVYYDKKGRS-------RFSYEFGTIAGSAATNGFVSFWVAVILYQSLVPISLYISVEIIKTAQAAFIYGDVLLYNAKLDYPCTPKSWNISDDLGQVEYIFSDKTGTLTQNVMEFKKCTINGVSYG-----------------------------------------------------------------------------------------------------------------------------------------------------RAYTEALAGLRKRQGIDVETEGRREKAEIAKDRD------------------------------------------------------------TMIDELRALSGNSQFYPEEVTFVSKEFVRDLKGASGEVQQRCCEHFMLALALCHSVLVEANPDNPKKLDLKAQSPDEAALVATARDVGFSFVGKTKKGLIIEMQGIQKEFEILNILEFNSSRKRMSCIVKIPGLNPGDEPRALLICKGADSIIYSRLSRQSGSNSEAILEKTALHLEQYATEGLRTLCIAQRELSWSEYEKWNEKYDIAAASLANREDELEVVADSIERELILLGGTAIEDRLQDGVPDCIELLAEAGIKLWVLTGDKVETAINIGFSCNLLNNEMELLVIKTTG-----DDVKEFGSEPSEIVDALLSKYLKEYFNLTGSE---------EEIFEAKKDHEFPKG----------NYAIVIDGDALKLALYG-------------------------------------------EDIRRKFLLLCKNCRAVLCCRVSPSQKAAVVKLVKDSLDVMTLAIGDGSNDVAMIQSADVGIGIAGEEGRQAVMCSDYAIGQFRYLARLVLVHGRWSYKRLAEMIPEFFYKNMIFALALFWYGIYNDFDGSYLYEYTYMMFYNLAFTSLPVIFLGILDQDVNDTISLVVPQLYRVGILRKEWNQRKFLWYMLDGLYQSIICFFFPYLVYHKNMIVTSNGLGLDHRYFVGVYVTTIAVISCNTYVLLHQYRWDWFSGLFIALSCLVVFAWTGIWSSA------IASREFFKAAARIYGAPSFWAVFFVAVLFCLLPRFTYDSFQKFFYPTDVEIVREMWQHGHFDHYPPGYDPTDPNRPKVTKAGQHGEKIIEGIALSDNLGGSNYSRDSVVTEEIPMTFMHGEDGSPSGYQKQETWMTSPKETQDLLQSPQFQQAQTFGRGPSTNVRSSLDRTREQMIATNQLDNRYSVERARTSLDLPGVTNAASLIGTQQNN-", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . :. . : : : . . : . . ::. : .: : : . * * *:* **. :**:* *: **:. **.*** *::* . :. : :**: :: :**:** :* * * ::** . : : :: * ::***::*:.:*: :.** :***:*: :. *::** :******** : * : .: : . : .* *: * .: *.: *.. .: :::***** :***. . *:*:*:* ***:* *.* * * : :. :*: : .:.*. :. .* : . *:: *: *: :::******:***:*: *: :* * :* . : ...:: .:.::***:.*************:* *:** *.* ** .: : :* * . .. : .: :: ::. :: *: *::**:*:.: . :: :* ****.*** :**:.*: * : . : :. . . : :* :*:**. ***** *:: * *****.:**.** .* *: :* * ****.:. : : . : * *: : .*: *: : : ** :: *:* *****:******. * * :*.**:******* *** ***::*::*.:: . . : . . . ...*: :. :* **:****:* *** **.*:* ..:**:****:*** **::*.:*:**:*:** ***:.***::.** :: **:****:*.* *:.::: *****. *:* *:.:: .:... :: :: .**: ::*:**: :.:::***.*. *: .* ** * :* .*: ::.* *:: *::* .: . : :* .. ... :: : . : : * . . : * : : :. * .::: * : * . . *. : :: : * . :: . * : . . ", "identical_positions": 297, "similar_positions": 348, "identity": "15.52%" }, { "cls_id": "homologset.agr.MGI:1859670", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A0G2JSN6-1", "uniprot_id": "A0A0G2JSN6_RAT", "id": "A0A0G2JSN6-1", "name": "Adhesion G protein-coupled receptor G3", "aln": "MATARSLG--LLLFLLLTSDENNGEEPRNPEEPRNVCR-LKEDYEYNTFDLSDIAQCFTKCGQSDTNSCEVGNLQRYWLNYESHLLEN-SMETVDMPFVKALIQNISTDVSEDLLYSLVPSQIPRQVMRGEDQPADRVRLPKSLFGALPGNRSAVRLAITILNIGPGNVFKGPRLLEDKGSSVLNNRMVGLSVGQMHATGLSEPVEITFSHQHQSPNVILTCVFWDMAKG---DWDSHGCSTEPGDGRTVCRCDHLTFFALLLRPTLDQATARTLTRISQAGSAVSMIFLAFTMVLYVAFRFSLQRFKSEDAPKIHMALSTSLFLLNLTFLINVGSGSQGPPASCWVRAAIFHYFLLCVFTWMGLEAFHLYLLVIKVFNTYFGHYFLKLSLLGWGLPVLIVIGVGSSNSYGVYTIRDQENRTSLELCWFQKEP---ALYATVHGYFLVTFLFGAVVLAMVAWKIFTLPSVTAGKGQGQTWKSVLTVLGLSSLVGMTWGLAVLTPLGLSTVYIFTLLNSLQGLFIFCWFIILYFPTQSTTTSSSGTARLDQAHSMSQE", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8R0T6-1", "uniprot_id": "AGRG3_MOUSE", "id": "Q8R0T6-1", "name": "Adhesion G protein-coupled receptor G3", "aln": "MATARSLG--LLFFLLLTSDEE------TTEEPRNVCRRLQEGHEYDTFDLNDTAQCFTKCGQSEHSPCDVGNLQRYWLNYESYLLEN-SMETVDMPFVKALIQNISTDVSEDLLYSLMLSQIPRQVMQGEDEPADGVRLPKSLFGALPGNRSAVRLAITVLDIGAGNVFKGPKLLEDKGSSVLNNRMVGLSVGQMHATGLSEPVEITFSHERQPPNVILTCVFWDMAKG---DWDSHGCSTVPGDGRTVCRCDHLTFFALLLRPILDLATAQTLTRISQAGSAVSMIFLAFTMVLYVAFRFSLQRFKSEDAPKIHMALSISLFLLNLTFLINVGSSSQGPPASCWVRAAIFHYFLLCVFTWMGLEAFHLYLLAIRVFNTYFGHYFLKLSLLAWGLPVLVVIGAGSSNSYGVYTIRDQENRTSLELCWFQKEP---ALYATVHGYFLVTFLFGAVVLALVAWKIFTLPSVTAGKGQGPTWKSVLTVLGLSSLVGMTWGLAVLTPLGLSTIYVFTLLNSLQGLFIFCWFIILYFPTQSTTASSSGTARLDQAHSVSQE", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q86Y34-1", "uniprot_id": "AGRG3_HUMAN", "id": "Q86Y34-1", "name": "Adhesion G protein-coupled receptor G3", "aln": "MATPRGLGALLLLLLLPTSGQE-----KPTEGPRNTCL--GSNNMYDIFNLNDKALCFTKCRQSGSDSCNVENLQRYWLNYEAHLMKEGLTQKVNTPFLKALVQNLSTNTAEDFYFSLEPSQVPRQVMKDEDKPPDRVRLPKSLFRSLPGNRSVVRLAVTILDIGPGTLFKGPRLGLGDGSGVLNNRLVGLSVGQMHVTKLAEPLEIVFSHQRPPPNMTLTCVFWDVTKGTTGDWSSEGCSTEVRPEGTVCCCDHLTFFALLLRPTLDQSTVHILTRISQAGCGVSMIFLAFTIILYAFLRLSRERFKSEDAPKIHVALGGSLFLLNLAFLVNVGSGSKGSDAACWARGAVFHYFLLCAFTWMGLEAFHLYLLAVRVFNTYFGHYFLKLSLVGWGLPALMVIGTGSANSYGLYTIRDRENRTSLELCWFREGTTMYALYITVHGYFLITFLFGMVVLALVVWKIFTLSRATAVKERGKNRKKVLTLLGLSSLVGVTWGLAIFTPLGLSTVYIFALFNSLQGVFICCWFTILYLPSQSTTVSSS-TARLDQAHSASQE", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "***.*.** **::** **.:: .* ***.* .. *: *:*.* * ***** ** ..*:* **********::*::: :.*: **:***:**:**:.:**: :** **:*****:.**:*.* ******** :******.****:*:*:**.*.:****:* ..**.*****:*********.* *:**:**.***:: .**: *******::** **.*.**** *** ************* ** :*.: ********..*********::**. :*:* :***********:**. *******:**:****.*:*. *:**.*.*:*******.**************.::***************:.****.*:***.**:****:*****:***********:: . *** *******:***** ****:*.******. .** * :* . *.***:********:*****::*******:*:*:*:*****:** *** ***:*:****.*** ********* ***", "identical_positions": 367, "similar_positions": 120, "identity": "65.89%" }, { "cls_id": "homologset.agr.MGI:1859682", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9WTW8-1", "uniprot_id": "S23A2_RAT", "id": "Q9WTW8-1", "name": "Solute carrier family 23 member 2", "aln": "----------------------------------------------MMGVGKNTS-KSVEVGGSTEGKYEEEAKRPDFFTLPVVINGGATSSGEQDNEDTELMAIYTTENGIAEKSSLAETLDSTGSLDPQRSDMIYTIEDVPPWYLCIFLGLQHYLTCFSGTIAVPFLLADAMCVGDDQWATSQLIGTIFFCVGITTLLQTTFGCRLPLFQASAFAFLAPARAILSLDKWKCNTTEITVANGTAELL--EHIWHPRIQEIQGAIIMSSLIEVVIGLLGLPGALLRYIGPLTITPTVALIGLSGFQAAGERAGKHWGIAMLTIFLVLLFSQYARNVKFPLPIYKSKKGWTAYKLQLFKMFPIILAILVSWLLCFIFTVTDVFPSNSTDYGYYARTDARKGVLLVAPWFKVPYPFQWGMPTVSAAGVIGMLSAVVASIIESIGDYYACARLSCAPPPPIHAINRGIFVEGLSCVLDGVFGTGNGSTSSSPNIGVLGITKVGSRRVIQYGAALMLGLGMIGKFSALFASLPDPVLGALFCTLFGMITAVGLSNLQFIDLNSSRNLFVLGFSIFFGLVLPSYLRQNP--LVTGITGIDQVLNVLLTTAMFVGGCVAFILDNTIPGTPEERGIKKWKKGVSKGNKSLDGMES--YNLPFGMNIIKKYRCFSYLPISPTFAGYTWKGFGKSENRRSSDKDSQATV------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9EPR4-1", "uniprot_id": "S23A2_MOUSE", "id": "Q9EPR4-1", "name": "Solute carrier family 23 member 2", "aln": "----------------------------------------------MMGIGKNTASKSVEAGGSTEGKYEEEAKHSNFFTLPVVINGGATSSGEQDNEDTELMAIYTTENGIAEKSSLAETLDSTGSLDPQRSDMIYTIEDVPPWYLCIFLGLQHYLTCFSGTIAVPFLLADAMCVGDDQWATSQLIGTIFFCVGITTLLQTTFGCRLPLFQASAFAFLAPARAILSLDKWKCNTTEITVANGTAELL--EHIWHPRIQEIQGAIIMSSLIEVVIGLLGLPGALLRYIGPLTITPTVALIGLSGFQAAGERAGKHWGIAMLTIFLVLLFSQYARNVKFPLPIYKSKKGWTAYKFQLFKMFPIILAILVSWLLCFIFTVTDVFPSNSTDYGYYARTDARKGVLLVAPWFKVPYPFQWGMPTVSAAGVIGMLSAVVASIIESIGDYYACARLSCAPPPPIHAINRGIFVEGLSCVLDGIFGTGNGSTSSSPNIGVLGITKVGSRRVIQYGAALMLGLGMVGKFSALFASLPDPVLGALFCTLFGMITAVGLSNLQFIDLNSSRNLFVLGFSIFFGLVLPSYLRQNP--LVTGITGIDQILNVLLTTAMFVGGCVAFILDNTIPGTPEERGIKKWKKGVSKGSKSLDGMES--YNLPFGMNIIKKYRCFSYLPISPTFAGYTWKGFGKSENSRSSDKDSQATV------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9UGH3-1", "uniprot_id": "S23A2_HUMAN", "id": "Q9UGH3-1", "name": "Solute carrier family 23 member 2", "aln": "----------------------------------------------MMGIGKNTTSKSMEAGSSTEGKYEDEAKHPAFFTLPVVINGGATSSGEQDNEDTELMAIYTTENGIAEKSSLAETLDSTGSLDPQRSDMIYTIEDVPPWYLCIFLGLQHYLTCFSGTIAVPFLLADAMCVGYDQWATSQLIGTIFFCVGITTLLQTTFGCRLPLFQASAFAFLAPARAILSLDKWKCNTTDVSVANGTAELLHTEHIWYPRIREIQGAIIMSSLIEVVIGLLGLPGALLKYIGPLTITPTVALIGLSGFQAAGERAGKHWGIAMLTIFLVLLFSQYARNVKFPLPIYKSKKGWTAYKLQLFKMFPIILAILVSWLLCFIFTVTDVFPPDSTKYGFYARTDARQGVLLVAPWFKVPYPFQWGLPTVSAAGVIGMLSAVVASIIESIGDYYACARLSCAPPPPIHAINRGIFVEGLSCVLDGIFGTGNGSTSSSPNIGVLGITKVGSRRVIQCGAALMLALGMIGKFSALFASLPDPVLGALFCTLFGMITAVGLSNLQFIDLNSSRNLFVLGFSIFFGLVLPSYLRQNP--LVTGITGIDQVLNVLLTTAMFVGGCVAFILDNTIPGTPEERGIRKWKKGVGKGNKSLDGMES--YNLPFGMNIIKKYRCFSYLPISPTFVGYTWKGLRKSDNSRSSDEDSQATG------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9PLA9-1", "uniprot_id": "A0A8M9PLA9_DANRE", "id": "A0A8M9PLA9-1", "name": "", "aln": "MCELDELAGQSVEHEIVLTGRSAVFLPEREWRRAADPQSVEDELSGGMGVGKNTTSKSMDS-TTEPGKYEEENKHSAHFYPIPVVNGVVQTAGDQDAEDTQLMAIYAKDSQTEDKCSISDTVDSADSIDAGRIDMIYTIEDTPPWYLCVFLGLQHYLTCFSGTIAVPFLLAEAMCVGFDQWATSQLIGTIFFCVGITTLLQTTFGCRLPLFQASAFAFLAPARAILSLEKWKCNATATLFLN-STELPHTEDIWYPRIREIQGAIIVSSLIEVVIGALGLPGVLLKYIGPLTITPTVTLIGLSGFQAAGERAGKHWGIAMLTIFLVLLFSQYARNIHLPLPVYKSKKGWTSYRLQLFKMFPIIMAILVSWFLCFIFTVTDVFPPEKDKYGFYARTDARQGILAAAPWFKIPYPFQWGLPTVTAAGVIGMLSAVVASIIESIGDYYACARLSGAPPPPIHAINRGIFTEGLSCVLDGVFGTGNGSTSSSPNIGVLGITKVGSRRVIQYGAAFMLLLGMVGKFSALFASLPDPVLGALFCTLFGMITAVGLSNLQFVDLNSSRNLFVLGFSIFFGLVLPSYLKENP--LVTGIVQIDQVLNVLLTTAMFVGGSVAFVLDNTIPGTAEERGIRKMNRGNSSSKR--ERMES--YDLPIGMDFLRRHRIFQYLPISPTFAGYQWSIFTHSCRNRKDESMPAKPELGESGV", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VH02-1", "uniprot_id": "Q9VH02_DROME", "id": "Q9VH02-1", "name": "", "aln": "--------------------------------------------------------------------------------------------MELNN--------VTIEDATDASKSYSQAANTPPSNEKPKPQLLYAINDNPPWYLSIFLAFQHYLTMIGAIVSIPFILTPALCMSDEDANRGIIISTMIFVTGIVTYFQATWGVRLPIVQGGTISFLVPTLAILALPQWKCPEQAVMDAMDEAERE---ELWQVRMRELSGAIAVSAMVQVILGYTGLVGKILKYVTPLTIVPTVSLVGLTLFEHAAETASKHWGIAVGTTGMLTLFSQIMSNVPVPILAYRKGHGLEIRQFQLFRLFPVLLTIMIMWGLCGILTATDVFPPSHP-----SRTDVRLNVLTSAKWFYVPYPGQFGWPSVTLSGVLGMLAGVLACTVESLSYYPTVSQMSGAHSPPLHAINRGIGTEGFGTVLAGLWGAGNGTNTFGENVGAIGVTKIGSRRVIQWAALIMVLQGVIGKFGAIFILIPDSVVGGIFCVMFGMIIAFGLSTLQYVDLRSARNLYILGLSIFFPMVLCRWMQKNPGAIDTGNKTVDSTLSVLLGTTILVGGVLGCLLDNIIPGTPEERGLIDWANEMPLGDDNVNDGTATDYDFPLGMDAIRRWKWTYYIPFMPTYKLQKQS-------------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : : :. . * ::: ::. * : : :::*:*:* *****.:**.:***** :.. :::**:*: *:*:. :: . :*.*::* .**.* :*:*:* ***:.*..:::**.*: ***:* :*** :* .:* *::*:.*** :*::::*::* ** * :*:*: ****.***:*:**: *: *.* *.******: * :: **** *: .*: *:. :* ::***::**::::*:: * ** *:*.*****.. :***.* .:* * ** :*** *:* *:*: :**:***:.*:*. :**:. * : :::* * .**:******* .**:. ** *::*:***:.: . *:*.:*:**:******* .* :*: *::***.*:* :**.*:*.:**.:**** *.***.**::**.*:***::**:**** :** ::::** : ** :*. *.*** *:::*** :. :*** ****.****: . . .. : : *::*:**: ::: : *:*: **: . ", "identical_positions": 232, "similar_positions": 200, "identity": "32.86%" }, { "cls_id": "homologset.agr.MGI:1859683", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O88796-1", "uniprot_id": "RPP30_MOUSE", "id": "O88796-1", "name": "Ribonuclease P protein subunit p30", "aln": "-----MAAFADLDLRAGSDLKALRGLVETAAHL---GYSVVAINHIVDFKEKKREIEKPIAVSELFTTLPIVQGKSRPIKILTRLTIIVTDPAHCNVLRATSSRVRLYDIVAVFPKTEKLFHVACTHLDVDLVCITVTEKLPFYFKRPPVNVA-----------------------------------IERGLGFELVYGPAIRDATMRRYTISNALNLMQICKGKNVILSSAAERPLEIRGPYDVANLGLLFGLSENDGKAAVSTNCRAVFLHGETRKT----------------------------AFGIISTVKKPRPSEADDESLPVCKKAKCEG", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8I6AG83-1", "uniprot_id": "A0A8I6AG83_RAT", "id": "A0A8I6AG83-1", "name": "", "aln": "-----MAAFADLDLRAGSDLKALRGLVETAAHL---GYSVVAINHIVDFKEKKREIEKPVAVSELFTTLPIVQGKSRPIKILTRLTIIVTDPSHCNVLRATSSRVRLYDIVAVFPKTEKLFHVACTHLDVDLVCITVTEKLPFYFKRPPINVALQVFISFSFIGGQVAWLSVGSVSLHMGTSFSLDRAIERGLGFELVYGPAIRDATMRRYTISNALNLMQICKGKNVILSSAAERPLEIRGPYDVANLGLLFGLSENEGKAAVSTNCRAAFLHGETRKT----------------------------AFGIISTVKKPRSSEAEDESLPACKKAKHEG", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P78346-1", "uniprot_id": "RPP30_HUMAN", "id": "P78346-1", "name": "Ribonuclease P protein subunit p30", "aln": "-----MAVFADLDLRAGSDLKALRGLVETAAHL---GYSVVAINHIVDFKEKKQEIEKPVAVSELFTTLPIVQGKSRPIKILTRLTIIVSDPSHCNVLRATSSRARLYDVVAVFPKTEKLFHIACTHLDVDLVCITVTEKLPFYFKRPPINVA-----------------------------------IDRGLAFELVYSPAIKDSTMRRYTISSALNLMQICKGKNVIISSAAERPLEIRGPYDVANLGLLFGLSESDAKAAVSTNCRAALLHGETRKT----------------------------AFGIISTVKKPRPSEGDEDCLPASKKAKCEG", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VPM0-1", "uniprot_id": "Q9VPM0_DROME", "id": "Q9VPM0-1", "name": "", "aln": "--MEQTRPFYDFSIPYNKDDSVLRALLNELVET---GYKTVAIDQSFDHSKKDPGKRGSEMFPEPHKIEHLRKEFQDKLRILQRITILYVDVNVAHAMSVSHN-LRKFNLIAGQPKTDAALTHCCTAFNGDLITFDPVAGSRLLVNRKAYQVA-----------------------------------VRRGMFFEIKYAPSICDSNNRKDMIKIAQNYCTKGKSKNVIFSSGAAHEFQLRGPYDVANLAFIFGLSEDQGKNAVDGHCRELFLKAEARRLGKTIMFLKGNGPIIYSDSSEDEKSTEDEMKGLKPQIGKADAFEVKDGTEHAIKRLKVA-", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P38786-1", "uniprot_id": "RPP1_YEAST", "id": "P38786-1", "name": "Ribonuclease P/MRP protein subunit RPP1", "aln": "MLVDLNVPWPQNSYADKVTSQAVNNLIKTLSTLHMLGYTHIAINFTVNHSEKFPNDVKLLNPIDIKRRFGELMDRTG-LKLYSRITLIIDDPSKGQSLSKISQ---AFDIVAALPISEKGLTLSTTNLDIDLLTFQYGSRLPTFLKHKSICSC-----------------------------------VNRGVKLEIVYGYALRDVQARRQFVSNVRSVIRSSRSRGIVIGSGAMSPLECRNILGVTSLIKNLGLPSDRCSKAMGDLASLVLLNGRLRNKSHKQTIVTGGGS-----GNGDDVVNDVQGIDDVQTIKVVKRSMDAEQLGHASKRHKP--", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : . ..:. *:: **. :**: .:..:* : ::: *:*:: * : : . ::::* * :: : . * :: **: : .:: . . : **: :*: *. :: * *: :. . . :.:.:::.*.* :: *. .*:.* :**... . *:. . :*:.. *. . : : . *: * ", "identical_positions": 32, "similar_positions": 89, "identity": "9.44%" }, { "cls_id": "homologset.agr.MGI:1859709", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O08773-1", "uniprot_id": "RGS14_RAT", "id": "O08773-1", "name": "Regulator of G protein signaling 14", "aln": "--------------------------------------------------------MPGKPKHLGVPNGR-------------------MVLAVSDGELTSTSGSQAQGEGRGSSLSIHSLPSGPSSPFSTDEQPVASWAQSFERLLQDPRGLAYFTEFLKKEFSAENVTFWQACERFQQIPASDTKQLAQEAHNIYHEFLSSQALSPVNIDRQAWLSEEVLAQPRPDMFRAQQLQIFNLMKFDSYARFVKSPLYQECLLAEAEGRPLREPGSSHLGSPDTARKKPKLKPGKSLPLGVEELGQLPLAE---GRPLRKSFRREMPGGAVNSALR-RESQGSLNSSASLDLGFLAFVSSKSESHRKSLGSGEGESESRPG---KYCCVYLPDGTASLALARPGLTIRDMLAGICEKRGLSLPDIKVYLVGKEQKALVLDQDCTVLADQEVRLENRITFQLELVGLERVVRISAKPTKRLQEALQPILAKHGLSLDQVVLHRPGEKQLVDLENLVSSVASQTLVLDTLPDAKTREASSIPPCRSQGCLPRTQTKDSHLPPLSSSLSVEDASGSTGKRQTCDIEGLVELLNRVQSSGAHDQRGLLRKEDLVLPEFLQLPSQRPGSQEAPP-------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P97492-1", "uniprot_id": "RGS14_MOUSE", "id": "P97492-1", "name": "Regulator of G protein signaling 14", "aln": "--------------------------------------------------------MPGKPKHLGVPNGR-------------------MVLAVSDGELTSTAGSQAQGEGRGSSLSIHSLPSGPSSPFSTEEQPVASWAQSFERLLQDPRGLAYFTEFLKKEFSAENVTFWKACERFQQIPASDTKQLAQEAHNIYHEFLSSQALSPVNIDRQAWLSEEVLAQPRPDMFRAQQLQIFNLMKFDSYARFVKSPLYQECLLAEAEGRPLREPGSSHLGSPDTARKKPKLKPGKSLPLGVEELGQLPLAEGPCGRPLRKSFRREMTGGAMNSALR-RESQGSLNSSASLDLGFLAFVSSKSESHRKSLGSGESESESRPG---KYCCVYLPDGTASLALARPGLTIRDMLAGICEKRGLSLPDIKVYLVGNEQKALVLDQDCTVLADQEVRLENRITFQLELVGLERVVRISAKPTKRLQEALQPILAKHGLSLDQVVLHRPGEKQPMDLENPVSSVASQTLVLDTPPDAKMSEARSISPCRSQGCLPRTQTKDSHLPPSSSSLLVEDASSSTGNRQTCDIEGLVELLNRVQSSGAHDQRGLLRKEDLVLPEFLQLPSQRPGSREAPP-------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O43566-7", "uniprot_id": "RGS14_HUMAN", "id": "O43566-7", "name": "Regulator of G protein signaling 14", "aln": "--------------------------------------------------------MPGKPKHLGVPNGR-------------------MVLAVSDGELSSTTGPQGQGEGRGSSLSIHSLPSGPSSPFPTEEQPVASWALSFERLLQDPLGLAYFTEFLKKEFSAENVTFWKACERFQQIPASDTQQLAQEARNIYQEFLSSQALSPVNIDRQAWLGEEVLAEPRPDMFRAQQLQIFNLMKFDSYARFVKSPLYRECLLAEAEGRPLREPGSSRLGSPDATRKKPKLKPGKSLPLGVEELGQLPPVEGPGGRPLRKSFRREL-GGTANAALR-RESQGSLNSSASLDLGFLAFVSSKSESHRKSLGSTEGESESRPG---KYCCVYLPDGTASLALARPGLTIRDMLAGICEKRGLSLPDIKVYLVGNEQ-ALVLDQDCTVLADQEVRLENRITFELELTALERVVRISAKPTKRLQEALQPILEKHGLSPLEVVLHRPGEKQPLDLGKLVSSVAAQRLVLDTLPGVKISKARDKSPCRSQGCPPRTQDKATHPPPASPSSLVKVPSSATGKRQTCDIEGLVELLNRVQSSGAHDQRGLLRKEDLVLPEFLQLPAQGPSSEETPPQTKSAAQPIGGSLNSTTDSAL----------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M3B8C4-1", "uniprot_id": "A0A8M3B8C4_DANRE", "id": "A0A8M3B8C4-1", "name": "", "aln": "MAGLPFQTGSDRAVR----KRLSRRCVCLRGGFRESLSLWAQSCQPDE-------DMSKKMSSLAVPTGL-------------------MTQAVSDGELNLRLSSCGSSSSLSESSSRSGGSQAADGPASR----VVSWAVCFEHLLEDHVGVRYFTEFLRSEVSAENILFYQACEKFKKIPTSRLEEMKKEARLIYDTFLSESSLHAVNIDDTAQTEERELEMPTPDMFNKAQAQIFKLMKMDSYTRFVRSPLYQNCMLACVESRPLPSIGTP--EPKSKMSKKSATPPSNRKSVELKVPSSDSKTSR-KKRLENRGSWG-ADQSFERMAVSRKESQISVKSNSSLELVSGSGRAENGRCSVAVSDPEALSSGSPT--ADKYCCVYLPDGTASLVSARAGLSLRDMISSLCEKRAFPLRDVLLYLRGKDK-PLSLDQDCSMFGDQQLSLELKITFALEIAFLGRTIGIIAKSSKSVGEALSSVLEKQQLRPQDVQLSLSGSNDALNMSTSVFRLANKTVRLDRAALEIQTS----SPS------------------ARANSRGR---------KHQDVDGLVELLNRAQCSRADDQRGLLTKEQLEIPQFLQLPAGGAEDQECAL-------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0AC58ID84-1", "uniprot_id": "A0AC58ID84_DANRE", "id": "A0AC58ID84-1", "name": "", "aln": "MEVQEWRRYSLWAASLTRMEQIQTQTVSFIMEISLSLQQQKPSVQSKEKRILSFNEITRGFSNLTRRNSLRRTIGRHNTMSDDHPHTLNKTLTVSDGELNVMSDEHAATQHSSSNSSLPTVPSEGSRGVGQ----VASWAVSFERLLEDPVGVCYFTAFLKSEVSAENILFWSACEKFRKIPGHQTEQLKREALSIYNTFLSSNATSPINIDDRVRVEEKDVQNPHADIFQKAQQQIFKLMKFDSYTRFVRSQLYQSCMLANVEGRPLPLLDSR--GKPLALSKQTNS----------NSPREQAKFDRTKERLKAKPSAADAEDVVERRKVN-LQGMMGKDKRKEKRGSWGESPISFKTGLVKSSEVEKLVSRSADGKVDKYCCVFLPDGTASLTPARPGLTVRNMLTGLCEKRRLPLSDIIIYLQGKDKQPLSLDQDSSVLQDQQVTLELRVTFAVKVAFTGKTVAVVVKSNKTLQEALAAMLNKYRLRSHEATVTMRDSGQKISLNTPVTFLANKALILDKGVDEASSSKGNFSPPSFQDRRGAVDANMFSPGMSRPNVRQRNP----GLRRTYDMEGLVELLNRAQCCSADDQRGLLKKEHLMLPQFLQLPLDEVEEAETCRSLEDSCSSMGSFEGDCTPRVQSDTLEEGPSERDCSNLARETVV", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :. . * .. . :******. . . . ... * .. . *.*** .**:**:* *: *** **:.*.****: *:.***:*::** ::: :** **. ***..: .:*** . *. : * .*:*. * ***:***:***:***:* **:.*:** .*.*** .: *:. : . . . * : . : :. . .. . . * * *****:********. **.**::*:*::.:**** :.* *: :** *::: .* ****.::: **:: ** ::** :::. :.: : .*..* : *** .:* * * :. : .. : :.: . * :* : : ** . .* .. . : *::********.*.. *.****** **.* :*:***** . * ", "identical_positions": 155, "similar_positions": 143, "identity": "23.17%" }, { "cls_id": "homologset.agr.MGI:1859730", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q6AYE2-1", "uniprot_id": "SHLB1_RAT", "id": "Q6AYE2-1", "name": "Endophilin-B1", "aln": "MNIMDFNVKKLAADAGTFLSRAVQFTEEKLGQAEKTELDAHLENLLSKAECTKVWTEKIMKQTEVLLQPNPNARIEEFVYEKLDRKAPSRINNPELLGQYMIDAGTEFGPGTAYGNALIKCGETQKRIGTADRELIQTSALNFLTPLRNFIEGDYKTIAKERKLLQNKRLDLDAAKTRLKKAKAAETK--------------------------------------SSSEQELRITQSEFDRQAEITRLLLEGISSTHAHHLRCLNDFVEAQMTYYAQCYQYMLDLQKQLGSFPSNYVSNNNQTSGTPVPYTLSNTIGPSAVASTGSLVITCPPNLSDLKDSSSTRKARVLYDYDAANSTELSLLADEVITVFSVVGMDSDWLMGERGNQKGKVPITYLELLN", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9JK48-1", "uniprot_id": "SHLB1_MOUSE", "id": "Q9JK48-1", "name": "Endophilin-B1", "aln": "MNIMDFNVKKLAADAGTFLSRAVQFTEEKLGQAEKTELDAHLENLLSKAECTKIWTEKIMKQTEVLLQPNPNARIEEFVYEKLDRKAPSRINNPELLGQYMIDAGTEFGPGTAYGNALIKCGETQKRIGTADRELIQTSALNFLTPLRNFIEGDYKTIAKERKLLQNKRLDLDAAKTRLKKAKAAETK--------------------------------------SSSEQELRITQSEFDRQAEITRLLLEGISSTHAHHLRCLNDFVEAQMTYYAQCYQYMLDLQKQLGSFPSNYLSNNNQTSGTPVPYALSNAIGPSAQASTGSLVITCPSNLNDLKESSNNRKARVLYDYDAANSTELSLLADEVITVFSVVGMDSDWLMGERGNQKGKVPITYLELLN", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9Y371-1", "uniprot_id": "SHLB1_HUMAN", "id": "Q9Y371-1", "name": "Endophilin-B1", "aln": "MNIMDFNVKKLAADAGTFLSRAVQFTEEKLGQAEKTELDAHLENLLSKAECTKIWTEKIMKQTEVLLQPNPNARIEEFVYEKLDRKAPSRINNPELLGQYMIDAGTEFGPGTAYGNALIKCGETQKRIGTADRELIQTSALNFLTPLRNFIEGDYKTIAKERKLLQNKRLDLDAAKTRLKKAKAAETR--------------------------------------NSSEQELRITQSEFDRQAEITRLLLEGISSTHAHHLRCLNDFVEAQMTYYAQCYQYMLDLQKQLGSFPSNYLSNNNQTSVTPVPSVLPNAIGSSAMASTSGLVITSPSNLSDLKECSGSRKARVLYDYDAANSTELSLLADEVITVFSVVGMDSDWLMGERGNQKGKVPITYLELLN", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M3AW37-1", "uniprot_id": "A0A8M3AW37_DANRE", "id": "A0A8M3AW37-1", "name": "Endophilin-B1", "aln": "---MDFNVKRFAADAGTLFSRAVQFTEEKFGQAEKTELDAHLETLLTRAECTKHWTEKILKQTEVLLQPNPNARIEELLYEKLDKKAPPRMNNHELMGQSMIDSGNEFGPGTAYGNALIKCGETEKQIGGAEREFIQTSAINFLTPFRNFLEGDFKTILKERKLLQNKRLDLDAAKTKLKKAKMADARAVPLRSTPPPGDVGYVANVSFMVNFLHVKWLKMWAEEVTTAEQDLKMTQSEFDRQAEITRLLLEGISSTHAHHLRCLNDFVEAQMTYYAQCYQYMVDLQKQLGNFPSAFTSNNNQSTASGG-AGVSVPILPLSTPLPSTTSNTS-SGFTEMQNFSGSRKARVLYDYDAAGSNELSLLADEVIMVSSVPGMDSDWLMGERGSQKGKVPITYLELLN", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A0R4IS36-1", "uniprot_id": "A0A0R4IS36_DANRE", "id": "A0A0R4IS36-1", "name": "Endophilin-B1", "aln": "---MEFNVRRLAADAGTFLSRAVQFTEEKFGQAEKTELDAHLEMLLSRAESTKHWTEKIMKQTEVVLQPNPNVRVEEFLYEILDKKVPTRANNHEMLGQCMIDSGHEFGPGTAYGSALIKCGETEKLLGSAEKEFIHSSAINFLTPFRNFIEGDFKTILKERKLLQNKRLDLDAAKNRMKKARVADARSAELNCSPPLG-EEYVAHFSYMLSFLHVRWLKLWTEEVKQAETELRIAQSEFDRQAEITRLLLEGISSTHAHHLRCLNDFVDAQAAYYAQCYQYTVNLQKQLGSFPSTFS-NNNQPSGSSS-ASVCVPTAPPAASLPAPPPSQASPALNELRSSSGTRKARVLYDYDAASSTELSLLADEVITVSSVPGMDSDWLMGQRGNQKGKVPITYLELLN", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *:***:::******::**********:************* **::**.** *****:*****:******.*:**::** **:*.*.* ** *::** ***:* *********.********:* :* *::*:*::**:*****:***:***:*** *****************.::***: *::: . :* :*:::*********************************:** :******** ::******.*** : ****.: : : . . : . .. . . :.:::. *..************.*.********** * ** *********:**.**************", "identical_positions": 243, "similar_positions": 77, "identity": "60.3%" }, { "cls_id": "homologset.agr.MGI:1859778", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9JHS2-1", "uniprot_id": "HIF3A_RAT", "id": "Q9JHS2-1", "name": "Hypoxia-inducible factor 3-alpha", "aln": "------------------------------------------------------------MDWDQDRSSTELRKEKSRDAARSRRSQETEVLYQLAHTLPFARGVSAHLDKASIMRLTISYLRMHRLCAAG------------------EWNQVR----------KEGEPLDACYLKALEGFVMVLTAEGDMAYLSENVSKHLGLSQLELIGHSIFDFIHPCDQEELQDALTPRPSLSKKKSEAA--------TGRHFSLRMKSTLTSRGRALNLKAATWKVLHCSGHMRAYKPPAQTSPAGSPRSEPPLQCLVLICEAIPHPAS--LEPPLGRGAFLSRHSLDMKFTYCDERIAEVAGYSPDDLIGCSAYEYIHALDSDAVSRSIHTLLSKGQAVTGQYRFLARTGGYLWTQTQATVVSGGRGPQSESIICVHFLISRVEENGVVLSLEQTEQHT------------------------------------------------------------------------------------------------------------------------------RRPPQLGTSSKKGIP--GNSLDPPAPRILAFLHPP---------------------------------------------------------------------------------------------------------ALSEASLAADPRRFCSPDLRRLMAPILDGPPTAATPSTPQAARRPQSPLPADLPDQLAVGLENAHRLSTARK----------------------------------------------------NKTMETDLDIAQDPDTPDLEMLAPYISMDDDFQLNSS--------------------------EQLPKVHRRPPR---------------------TARRPRARSFHGLSPPIPEA-----------------------------TLLPRWGSDPRLNCSSPSKGDPPTAPLTPRTRKRALAQSSEDK---------------------------------------------------------------------------------------------GLELLETKPPKRSPRLEPGSVLLPPLSLSFLLQGRQLPGNQPD-----------------------------------------------PRAPLVDSHEPLG-----------------------------LAPSLLSLYQHEETIQSRNHFLPAAGLAQTH---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q0VBL6-1", "uniprot_id": "HIF3A_MOUSE", "id": "Q0VBL6-1", "name": "Hypoxia-inducible factor 3-alpha", "aln": "------------------------------------------------------------MDWDQDRSNTELRKEKSRDAARSRRSQETEVLYQLAHTLPFARGVSAHLDKASIMRLTISYLRMHRLCAAG------------------EWNQVE----------KGGEPLDACYLKALEGFVMVLTAEGDMAYLSENVSKHLGLSQLELIGHSIFDFIHPCDQEELQDALTPRPNLSKKKLEAP--------TERHFSLRMKSTLTSRGRTLNLKAATWKVLHCSGHMRAYKPPAQTSPAGSPRSEPPLQCLVLICEAIPHPAS--LEPPLGRGAFLSRHSLDMKFTYCDERIAEVAGYSPDDLIGCSAYEYIHALDSDAVSRSIHTLLSKGQAVTGQYRFLARTGGYLWTQTQATVVSGGRGPQSESIICVHFLISRVEETGVVLSLEQTEQHT------------------------------------------------------------------------------------------------------------------------------RRPPRLSASSQKGIP--GNSVDSPAPRILAFLHPP---------------------------------------------------------------------------------------------------------ALSEASLAADPRRFCSPDLRRLMAPILDGPPPAATPSTPQATRRPQSPLPADLPDKLTVGLENAHRLSTAQK----------------------------------------------------NKTVETDLDIAQDPDTLDLEMLAPYISMDDDFQLNSS--------------------------EQLPKVHRRPPR---------------------VARRPRARSFHGLSPPIPEP-----------------------------SLLPRWGSDPRLNCSSPSRGDRPTASLMPGTRKRALAQSSEDK---------------------------------------------------------------------------------------------GLELLETKPPKRSPRLEPGSFLLPPLSLSFLLQGRQLPGNQQD-----------------------------------------------PRAPLVHSHEPLG-----------------------------LAPSLLSLCQHEETVQPRNRFPPAAGLGQTH---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9Y2N7-1", "uniprot_id": "HIF3A_HUMAN", "id": "Q9Y2N7-1", "name": "Hypoxia-inducible factor 3-alpha", "aln": "----------------------------------------------------------MALGLQRARSTTELRKEKSRDAARSRRSQETEVLYQLAHTLPFARGVSAHLDKASIMRLTISYLRMHRLCAAG------------------EWNQVG----------AGGEPLDACYLKALEGFVMVLTAEGDMAYLSENVSKHLGLSQLELIGHSIFDFIHPCDQEELQDALTPQQTLSRRKVEAP--------TERCFSLRMKSTLTSRGRTLNLKAATWKVLNCSGHMRAYKPPAQTSPAGSPDSEPPLQCLVLICEAIPHPGS--LEPPLGRGAFLSRHSLDMKFTYCDDRIAEVAGYSPDDLIGCSAYEYIHALDSDAVSKSIHTLLSKGQAVTGQYRFLARSGGYLWTQTQATVVSGGRGPQSESIVCVHFLISQVEETGVVLSLEQTEQHS------------------------------------------------------------------------------------------------------------------------------RRPIQRGAPSQKDTPNPGDSLDTPGPRILAFLHPP---------------------------------------------------------------------------------------------------------SLSEAALAADPRRFCSPDLRRLLGPILDGASVAATPSTPLATRHPQSPLSADLPDELPVGTENVHRLFTSGKD---------------------------------------------------TEAVETDLDIAQDADALDLEMLAPYISMDDDFQLNAS--------------------------EQLPRAYHRPLG---------------------AVPRPRARSFHGLSPPALEP-----------------------------SLLPRWGSDPRLSCSSPSRGDPSASSPMAGARKRTLAQSSEDEDE-------------------------------------------------------------------------------------------GVELLGVRPPKRSPSPEHENFLLFPLSLSFLLTGGPAPGSLQD-----------------------------------------------PSTPLLNLNEPLG-----------------------------LGPSLLSPYSDEDTTQPGGPFQPRAGSAQAD---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q24167-1", "uniprot_id": "SIMA_DROME", "id": "Q24167-1", "name": "Protein similar", "aln": "MVSLIDTIEAAAEKQKQSQAVVTNTSASSSSCSSSFSSSPPSSSVGSPSPGAPKTNLTASGKPKEKRRNNEKRKEKSRDAARCRRSKETEIFMELSAALPLKTDDVNQLDKASVMRITIAFLKIREMLQFVPSLRDCNDDIKQDIETAEDQQEVKPKLEVGTEDWLNGAEARELLKQTMDGFLLVLSHEGDITYVSENVVEYLGITKIDTLGQQIWEYSHQCDHAEIKEALSLKRELAQKVKDEPQQNSGVSTHHRDLFVRLKCTLTSRGRSINIKSASYKVIHITGHLVVNAKGER--------------LLMAIGRPIPHPSN--IEIPLGTSTFLTKHSLDMRFTYVDDKMHDLLGYSPKDLLDTSLFSCQHGADSERLMATFKSVLSKGQGETSRYRFLGKYGGYCWILSQATIVYDKLKPQS--VVCVNYVISNLENKHEIYSLAQQTAASEQKEQHHQAAETEKEPEKAADPEIIAQETKETVNTPIHTSELQAKPLQLESEKAEKTIEETKTIATIPPVTATSTADQIKQLPESNPYKQILQAELLIKRENHSPGPRTITAQLLSGSSSGLRPEEKRPKSVTASVLRPSP--APPLTPPPTAVLCKKTPLGVEPNLPPTTTATAAIISSSNQQLQIAQQTQLQNPQQPAQDMSKGFCSLFADDGRGLTMLKEEPDDLSHHLASTNCIQLDEMTPFSDMLVGLMGTCLLPEDINSLDSTTCSTTASGQHYQSPSSSSTSAPSNTSSSNNSYANSPLSPLTPNSTATASNPSHQQQQQHHNQQQQQQQQQQHHPQHHDNSNSSSNIDPLFNYREESNDTSCSQHLHSPSITSKSPEDSSLPSLCSPNSLTQEDDFSFEAFAMRAPYIPIDDDMPLLTETDLMWCPPEDLQTMVPKEIDAIQQQLQQLQQQHHQQYAGNTGYQQQQQQPQLQQQHFSNSLCSSPASTVSSLSPSPVQQHHQQQQAAVFTSDSSELAALLCGSGNGTLSILAGSGVTVAEECNERLQQHQQQQQQTSGNEFRTFQQLQQELQLQEEQQQRQQQQQQQQQQQQQQQLLSLNIECKKEKYDVQMGGSLCHPMEDAFENDYSKDSANLDCWDLIQMQVVDTEPVSPNAASPTPCKVSAIQLLQQQQQLQQQQQQQQNIILNAVPLITIQNNKELMQQQQQQQQQQQQEQLQQPAIKLLNGASIAPVNTKATIRLVESKPPTTTQSRMAKVNLVPQQQQHGNKRHLNSATGAGNPVESKRLKSGTLCLDVQSPQLLQQLIGKDPAQQQTQAAKRAGSERWQLSAESKQQKQQQQQSNSVLKNLLVSGRDDDDSEAMIIDEDNSLVQPIPLGKYGLPLHCHTSTSSVLRDYHNNPLISGTNFQLSPVFGGSDSSGGDGETGSVVSLDDSVPPGLTACDTDASSDSGIDENSLMDGASGSPRKRLSSTSNSTNQAESAPPALDVETPVTQKSVEEEFEGGGSGSNAPSRKTSISFLDSSNPLLHTPAMMDLVNDDYIMGEGGFEFSDNQLEQVLGWPEIA", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "A0A8M2B8B7-1", "uniprot_id": "A0A8M2B8B7_DANRE", "id": "A0A8M2B8B7-1", "name": "Hypoxia-inducible factor 1-alpha", "aln": "-------------------------------------MTSMNLETGGEDCHGKARRKQTFIEQKKRRVCTEWRKTCSRLAAQSRRKKESQLFKELTALLPLDLSMDGQRDKASVIRLTIAYLHLRGLLDTTDS--------------LMKRPSPG---------VSDKSHERELLDSALGGFVVLLSLNGKVIFATKGLTTHTGINQMDLIGRSLLEFLHPCDQMEVKDILTR-----LIGNQEP--------QKCEVFLRIK-------KAMNTKLTGWKIIQCSGKKRSSATPGSS-------------CLVLECRVLPIQEITEVDEALNACTFMSVHSPDMTFTYCHSRVVKLIGFRDTDLLGQSVYQYYHPSDCQQIRKAHICLLSKGQVSTGKYRLLHRYGGYVWAETDASLVCNSQTGVPESVVCINYILSEVEQPNLPFLLEKTEQLL-------------------------------------------------------------------------------------------------------------------------------KPTSSSYCPETEPAPFPPSRGQEGEKDLKESNEH-----------------------------------------------------------------------------------------------------------NSFITHLKQRDGDIQEVECTEIPHNTEGCYDFNCDQCELDLDSLAPYIPMHGEDFLLTPIIDRAMDMPELN----------------------------------------------------TCRPSCSSPSQNLDSSEGTTVLPVKSLNSTQQSVSN---------------------------SFQTKRISDTN--------------------LISTKQWSDSFDLVN-----------------------------------KVSKVYDYDPKQHNYQLFSSETKANHWVEEALKFPQPNRVHWN-------------------------------------------------------------------------------------------------IDGSTPPWICDGHLNHLEPKFRSLPEKTNCPPQKRRHQHEVK--------------------------------------------TAAALLTLPVLSG-----------------------------WECEVNAPLEHTSYLLQGTEIMAVLDQVASRVPWC-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .. * .* ** ** **:.**.:*:::: :*: **: . : ****::*:**::*::: : . . .:: **:::*: :*.: : ::.: : *:.::: :*:.: :: * **: *::: *: : . . :*:* :::* * : :*::: :*: *: . :* :: .*. :*:: ** ** *** ..:: .: *: **:. * :. * *.: : : :***** *.:**:* : *** * ::*::* . . ::*:::::*.:*: * : :* . . * . . : . * . . :. . .. : . :: . * .::. :. .: : :. :. .: . . . . : . : . . .* . . . *: * .: . . ", "identical_positions": 82, "similar_positions": 173, "identity": "5.37%" }, { "cls_id": "homologset.agr.MGI:1859815", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9Z0V5-1", "uniprot_id": "PRDX4_RAT", "id": "Q9Z0V5-1", "name": "Peroxiredoxin-4", "aln": "METWSKLLDGTTPSRRW-RKLVLLLPPLLLFLLQTEALQGLESDDRFRTRENECHFYAGGQVYPGEVSRVSVADHSLHLSKAKISKPAPYWEGTAVINGEFKELKLTDYRGKYLVFFFYPLDFTFVCPTEIIAFGDRIEEFKSINTEVVACSVDSQFTHLAWINTPRRQGGLGPIRIPLLSDLNHQISKDYGVYLEDSGHTLRGLFIIDDKGVLRQITLNDLPVGRSVDETLRLVQAFQYTDKHGEVCPAGWKPGSETIIPDPAGKLKYFDKLN-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O08807-1", "uniprot_id": "PRDX4_MOUSE", "id": "O08807-1", "name": "Peroxiredoxin-4", "aln": "MEARSKLLDGTTASRRWTRKLVLLLPPLLLFLLRTESLQGLESDERFRTRENECHFYAGGQVYPGEASRVSVADHSLHLSKAKISKPAPYWEGTAVINGEFKELKLTDYRGKYLVFFFYPLDFTFVCPTEIIAFGDRIEEFKSINTEVVACSVDSQFTHLAWINTPRRQGGLGPIRIPLLSDLNHQISKDYGVYLEDSGHTLRGLFIIDDKGVLRQITLNDLPVGRSVDETLRLVQAFQYTDKHGEVCPAGWKPGSETIIPDPAGKLKYFDKLN-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q13162-1", "uniprot_id": "PRDX4_HUMAN", "id": "Q13162-1", "name": "Peroxiredoxin-4", "aln": "MEALP-LLAATTPDHGRHRRLLLL--PLLLFLLPAGAVQGWETEERPRTREEECHFYAGGQVYPGEASRVSVADHSLHLSKAKISKPAPYWEGTAVIDGEFKELKLTDYRGKYLVFFFYPLDFTFVCPTEIIAFGDRLEEFRSINTEVVACSVDSQFTHLAWINTPRRQGGLGPIRIPLLSDLTHQISKDYGVYLEDSGHTLRGLFIIDDKGILRQITLNDLPVGRSVDETLRLVQAFQYTDKHGEVCPAGWKPGSETIIPDPAGKLKYFDKLN-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9V3Q4-1", "uniprot_id": "Q9V3Q4_DROME", "id": "Q9V3Q4-1", "name": "thioredoxin-dependent peroxiredoxin", "aln": "------------------------MSKYLSVLLLSAALVGAAKPED----NESCYSFAGGSVYPDQPK----GDHQLQYTKAVISKPAPQFEGTAVVNKEIVKLSLSQYLGKYVVLLFYPLDFTFVCPTEIIAFSDRIAEFKKIKTEVIGVSVDSHFTHLAWINTPRKEGGLGDVKIPLLSDLTHKISKDYGVYLESSGHALRGLFIIDQTGVLRQITMNDLPVGRSVDETIRLVQAFQYTDTHGEVCPAGWRPGADTIVPNPEEKTKYFAKNN-", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P34760-1", "uniprot_id": "TSA1_YEAST", "id": "P34760-1", "name": "Peroxiredoxin TSA1", "aln": "-------------------------------------------------------------------------------MVAQVQKQAPTFKKTAVVDGVFDEVSLDKYKGKYVVLAFIPLAFTFVCPTEIIAFSEAAKKFEEQGAQVLFASTDSEYSLLAWTNIPRKEGGLGPINIPLLADTNHSLSRDYGVLIEEEGVALRGLFIIDPKGVIRHITINDLPVGRNVDEALRLVEAFQWTDKNGTVLPCNWTPGAATIKPTVEDSKEYFEAANK", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "Q04120-1", "uniprot_id": "TSA2_YEAST", "id": "Q04120-1", "name": "Peroxiredoxin TSA2", "aln": "-------------------------------------------------------------------------------MVAEVQKQAPPFKKTAVVDGIFEEISLEKYKGKYVVLAFVPLAFSFVCPTEIVAFSDAAKKFEDQGAQVLFASTDSEYSLLAWTNLPRKDGGLGPVKVPLLADKNHSLSRDYGVLIEKEGIALRGLFIIDPKGIIRHITINDLSVGRNVNEALRLVEGFQWTDKNGTVLPCNWTPGAATIKPDVKDSKEYFKNANN", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * :.* ** :: ***:: : ::.* .* ***:*: * ** *:*******:**.: :*.. ::*: *.**.:: *** * **::**** :.:***:* .*.:*:**** :*..* :******** .*::*:**:***.***.*:*::***:.**:**.:* * *..* **: ** * . :** * ", "identical_positions": 92, "similar_positions": 61, "identity": "33.45%" }, { "cls_id": "homologset.agr.MGI:1859821", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9R063-1", "uniprot_id": "PRDX5_RAT", "id": "Q9R063-1", "name": "Peroxiredoxin-5, mitochondrial", "aln": "MVQLRFCVLGSIAGSVLRASATWTCVAGRAGRKGAG-WECGGARSFSSAAVTMAPIKVGDTIPSVEVFEGEPGKKVNLAELFK-DKKGVLFGVPGAFTPGCSKTHLPGFVEQAGALK-AKGAQVVACLSVNDAFVTAEWGRAHQAEG--KVQLLADPTGAFGKETDLLLDDSLVSLFGNRRLKRFSMVIDKGVVKALNVEPD-GTGLTCSLAPNILSQL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P99029-1", "uniprot_id": "PRDX5_MOUSE", "id": "P99029-1", "name": "Peroxiredoxin-5, mitochondrial", "aln": "MLQLGLRVLGCKASSVLRAS---TCLAGRAGRKEAG-WECGGARSFSSSAVTMAPIKVGDAIPSVEVFEGEPGKKVNLAELFK-GKKGVLFGVPGAFTPGCSKTHLPGFVEQAGALK-AKGAQVVACLSVNDVFVIEEWGRAHQAEG--KVRLLADPTGAFGKATDLLLDDSLVSLFGNRRLKRFSMVIDNGIVKALNVEPD-GTGLTCSLAPNILSQL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P30044-1", "uniprot_id": "PRDX5_HUMAN", "id": "P30044-1", "name": "Peroxiredoxin-5, mitochondrial", "aln": "MGLAGVCALRRSAGYILVGGAGGQSAAAAARRYSEGEWASGGVRSFSRAAAAMAPIKVGDAIPAVEVFEGEPGNKVNLAELFK-GKKGVLFGVPGAFTPGCSKTHLPGFVEQAEALK-AKGVQVVACLSVNDAFVTGEWGRAHKAEG--KVRLLADPTGAFGKETDLLLDDSLVSIFGNRRLKRFSMVVQDGIVKALNVEPD-GTGLTCSLAPNIISQL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P38013-1", "uniprot_id": "AHP1_YEAST", "id": "P38013-1", "name": "Peroxiredoxin AHP1", "aln": "-------------------------MSDLVN------------KKFPAGDYKFQYIAISQSDADSESCKMP--QTVEWSKLISENKKVIITGAPAAFSPTCTVSHIPGYINYLDELVKEKEVDQVIVVTVDNPFANQAWAKSLGVKDTTHIKFASDPGCAFTKSIGFELAVGDGVYWSG----RWAMVVENGIVTYAAKETNPGTDVTVSSVESVLAHL", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . :.*. . : * :.:: . * : :.*: ::*:. .** :: *.*.**:* *: :*:**::: * * .: * ::*:: *. *.:: .:. :::: :** ** * .: * . :.. *::**::.*:*. *.: **.:* * . .::::*", "identical_positions": 39, "similar_positions": 73, "identity": "17.81%" }, { "cls_id": "homologset.agr.MGI:1859822", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q149L7-1", "uniprot_id": "CRTAM_MOUSE", "id": "Q149L7-1", "name": "Cytotoxic and regulatory T-cell molecule", "aln": "MWWGALSLLFWVPVQAAFLK--METVTVEEGQTLTLTCVTSQTKNVSLQWLAPSGFTIFLNQHPALKSSKYQLLHHSATQLSISVSNVTLREEGVYTCLHYGSSVKTKQVRVTVLVTPFQPTVEALVLRRQNGEKSVVLKCSTERSKPPPQITWLLGEGLEIYGELNHEFEADGKICNTSSMLIARAYGKNSTVHCIIQHEGLHGRKLVAPFQFEDLVADQETSDQETSDAPEQSSLSSQALQQPTSTVSMMENSSIPETDKEEKEHATQDPGLSTEASAQHTGLARRKSGILLLTLVSFLIFILFIIVQLFIMKLRKAHVVWKKESEISEQALESYRSRSNNEETSSQENSSQAPQSKRCMNYITRLYSGAKTKKS--AQHWKLGGKHSRVPESIV", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8I5ZNM6-1", "uniprot_id": "A0A8I5ZNM6_RAT", "id": "A0A8I5ZNM6-1", "name": "", "aln": "MWWGTLSLLFCVPVQAAFLN--METIEVEEGQTLNLTCVTSLTKNASLQWLAPSGFTIFLNQHPALKSSKYQLLHHSATQLSVSVSNVTLREEGVYTCLHYGSSVKTKQVRVTVLVTPFQPTVEALVLRRQNGEKSVVLKCSTERSKPPPQVTWLLGGGLEIDGELHHEFEADGKISNTTSTLVVRSYGKNSTVHCVIRHKGLQGRKLVAPFRFGDLVADQET----TSEAPEQSSLSSQALQQPTSTVSMMENSSMPETDKEEKEHATQDPVMITEASAQHSGLARRNSGILLLTLVSFLIFILFIIIQLFIMKLRKAHVIWKKESEISEQALESYRSRSNNEETSSQENNSQASQSKHCMNYIMRLYSGAKTKKS--ARHWKMEGKHSRVPESIV", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O95727-1", "uniprot_id": "CRTAM_HUMAN", "id": "O95727-1", "name": "Cytotoxic and regulatory T-cell molecule", "aln": "MWWRVLSLLAWFPLQEASLTNHTETITVEEGQTLTLKCVTSLRKNSSLQWLTPSGFTIFLNEYPALKNSKYQLLHHSANQLSITVPNVTLQDEGVYKCLHYSDSVSTKEVKVIVLATPFKPILEASVIRKQNGEEHVVLMCSTMRSKPPPQITWLLGNSMEVSGGTLHEFETDGKKCNTTSTLIIHTYGKNSTVDCIIRHRGLQGRKLVAPFRFEDLVTDEET----ASDALERNSLSSQDPQQPTSTVSVTEDSSTSEIDKEEKEQTTQDPDLTTEANPQYLGLARKKSGILLLTLVSFLIFILFIIVQLFIMKLRKAHVIWKKENEVSEHTLESYRSRSNNEETSSEEKNGQSSHPMRCMNYITKLYSEAKTKRKENVQHSKLEEKHIQVPESIV", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*** .**** .*:* * *. **: *******.*.**** ** *****:*********::****.**********.***::*.****::****.****..**.**:*:* **.***:* :** *:*:****: *** *** *******:***** .:*: * ****:*** .**:* *: ::*******.*:*:*.**:********:* ***:*:** :*:* *:.***** ********: *:** .* ******::**** : ***..*: ****::*******************:************:****.*:**::***************:*:..*:.:. :***** :*** ****:. .:* *: ** :******", "identical_positions": 264, "similar_positions": 84, "identity": "66.5%" }, { "cls_id": "homologset.agr.MGI:1859823", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8TBJ5-1", "uniprot_id": "FEZF2_HUMAN", "id": "Q8TBJ5-1", "name": "Fez family zinc finger protein 2", "aln": "--------------------MASSAS--LETMVPPACPRAG---ASPATSK---TLAFSIERIMAKTSEPRAPFEPRPG----ALEADGSQGKKLLNLCSPLPCMIPLQPLGYEVPSKTLLSYSELWKSSLRAGGGGGGGGGGGGGGGGAPVCGASGLCKTNCGVCCKAELGLAPSALPAGRVIKPQVINQAVGLPASGSLYYFNYLDSTAYPPSELLS---GHLFPSGLLNAQAPAALAAHPKLFLLENAKLAGLAADKFPHPAPYPHKERLPAPLEQVLKENSALTAERGGVKGHS---------KLPGGSADGKPKNFTCEVCGKVFNAHYNLTRHMPVHTGARPFVCKVCGKGFRQASTLCRHKIIHTQEKPHKCNQCGKAFNRSSTLNTHIRIHAGYKPFVCEFCGKGFHQKGNYKNHKLTHSGEKQYKCTICNKAFHQVYNLTFHMHTHNDKKPFTCATCGKGFCRNFDLKKHVRKLHDS---VGP-AAPSAKDLTRTVQS-----------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9ESP5-1", "uniprot_id": "FEZF2_MOUSE", "id": "Q9ESP5-1", "name": "Fez family zinc finger protein 2", "aln": "--------------------MASSAS--LETMVPPACPRAG---ASPATSK---TLAFSIERIMAKTSEPRAPFEPRPA----ALEADSSQSKKLLNLCSPLPCMIPLQPLGYEVPSKTLLSYSEFWKSSLRAGGGGGGGSGGG-----APVCGASGLCKTNCGVCCKAELGLAPSALPAGRVIKPQVINQAVGLPASGSLYYFNYLDSTAYPPSELLG---GHLFPSGLLNAQAPTSLAAHPKLFLLENAKLASLAADKFPHPASYPHKERLHAPLEQVLKENSALTAERGGVKSHS---------KLPGGSTDSKPKNFTCEVCGKVFNAHYNLTRHMPVHTGARPFVCKVCGKGFRQASTLCRHKIIHTQEKPHKCNQCGKAFNRSSTLNTHIRIHAGYKPFVCEFCGKGFHQKGNYKNHKLTHSGEKQYKCTICNKAFHQVYNLTFHMHTHNDKKPFTCATCGKGFCRNFDLKKHVRKLHDS---VGPTATPSAKDLARTVQS-----------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q804Q5-1", "uniprot_id": "FEZF2_DANRE", "id": "Q804Q5-1", "name": "Fez family zinc finger protein 2", "aln": "--------------------MASSLP--LETVMS--CPRLDDRSGATAAPK---SLAFSIDRIMSKTSEPKA-----------AAAEERSEGKKTVGLCSPIPCMIPIQPFSYDLQAKALMNYSEFWKVNFRG-----------------ALCTSAAMCKTNCGVCSKADAGIKHSVLPGTRVIKPQVIHQALAMPANGSLCYFNYLDS-AY-QSELLS---GHLFSSAIANSQA-QAISAHQKLLLLENAKLACVSPEKFPTPQ-YPHKEHLPGQLDQIVRESHNLTE-KNGVKAHS---------KTNNCSSDGKPKNFTCEVCGKVFNAHYNLTRHMPVHTGARPFVCKVCGKGFRQASTLCRHKIIHTQEKPHKCNQCGKAFNRSSTLNTHIRIHAGYKPFVCEFCGKGFHQKGNYKNHKLTHSGEKQYKCSICSKAFHQIYNLTFHMHTHNDKKPFTCGTCGKGFCRNFDLKKHIRKLHDN---ANC--LSGGNDSSRGHQN-----------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VQ56-1", "uniprot_id": "ERM_DROME", "id": "Q9VQ56-1", "name": "Fez family zinc finger protein erm", "aln": "MVYFSPRGMQPCSPAGEIAMMPPSKSPVMESAASEQNPAQQSQQQDEQSAKRACPLKFSIAKIMEPDHRPSQVPPPQPAPVSFATNDDDEDEDPEIDADSERSCS-PIEVISLD-QSPSTVNYDSAFKKYVPGPCSGATSSVASPPSTAAVQQFVSSRHQELLSQYPLLYYAPNQLMCAAAAAQYAALTAQQQSLASAAHLSSFTASLNASLHHSQSLRRNLGHPLAAAAAVAAVAQSQAVPNLQHTLEKSPVAQRTAQ-SSGLQANLKRKRSPQDQGEVTPPPASTATSATGARSRSPSPQGSIEDSSPGSASGGKPKTFSCLECGKVFNAHYNLTRHMPVHTGARPFVCKVCGKGFRQASTLCRHKIIHTSEKPHKCQTCGKAFNRSSTLNTHSRIHAGYKPFVCEYCGKGFHQKGNYKNHKLTHSGEKAYKCNICNKAFHQVYNLTFHMHTHNDKKPYTCRVCAKGFCRNFDLKKHMRKLHEIGGDLDDLDMPPTYDRRREYTRREPLASGYGQASGQLTPDSSSGSMSPPINVTTPPLSSGETSNPAWPRSAVSQYPPGGFHHQLGVAPPHDYPSGSAFLQLQPQQPHPQSQQHHQQQQRLSETFIAKVF", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *..* . :*: . * :.* .* *** :** .* * : .: . :. * .* *:: :. : : : :.*.. :* . . :. : . . .. . . : * .:.: . * *. . : *: * ** :.:. : . : :. **:: :* :.: . :::: :: : *.:.:* . . ::..***.*:* ***********************************************.******: ************** ************:********************** ***.**.*****:***************:** .*.************:****: . . * * ", "identical_positions": 182, "similar_positions": 99, "identity": "29.64%" }, { "cls_id": "homologset.agr.MGI:1859834", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P10716-1", "uniprot_id": "CLC4F_RAT", "id": "P10716-1", "name": "C-type lectin domain family 4 member F", "aln": "MKEAELNRDVAKFCTDNQCVILQPQGLGPKSAAPMAPRTLRHVQAIVALVVVTVFFSLLALFVVVLQPWRQKQNEDHPVKAGLHGGNYSGS-----DNCSQFVRRAEMQEAIQSLRASG-NSSSCHKEIQTLKYQMDNVSSQVQLLGGHLEEANADIQQAKDVLKGTGALASETQALRSSLEVASADIHSLRGDLEKANAMTSQTQGLLKSSTDNTSAELHVLGRGLEEAQSEIQALRGSLQSS-----------------------------------------------------------NDLGSRTQNFLQHSMDNISAEIQAMRDGMQRAGEEMTSLKKDLETLTAQIQNANGHLEQTDTQIQGLKAQLKSTSSLNSQIEVVN--GKLKDSSRELQTLRRDLSDVSALKSNVQMLQSNLQKAKAEVQSLKTGLEAT-KTLAAKIQGQQSDLEALQKAVAAHTQGQKTQNQVLQLIMQDWKYFNGKFYYFSRDKKSWHEAENFCVSQGAHLASVTSQEEQ----AFLVQITNAVDHWIGLTDQGTEG-NWRWVDGTPFDYVQSRRFW----RKGQPDNWRHGNGEREDCVHLQRMWNDMACGTAYNWVCKKS----TDWSVARTDQS--------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P70194-1", "uniprot_id": "CLC4F_MOUSE", "id": "P70194-1", "name": "C-type lectin domain family 4 member F", "aln": "MKEAELNRDMARYCTDNQCVSLQPQGLGPKSAALMAPRTLRHVQVILALMVVTVIFSLLALFVVASQPWRPEWNKEPPSLL-LRGSNNSGH-----DNHSQFVRETEMQVAIQRLRDYEENSSSCHKEVQILKYQMDNVSSLVQLLGSHLEDVNADILQTKDVLKESGALALETQALRSSLEVASADIHSLRGDLEKANAMTSQTRGLLKSSTENTSAELHVLGRGLEEAQSEIQALRGSLQSA-----------------------------------------------------------NDLSSQTQGFLQHSMDNISAQIQTVRDGMERAGEKMNSLKKELETLTAQTQKANGHLEQTDAQIQGLKAELKSTSSLNSRIEVVN--GQMKDASRELQTLRRDLSDVSALKSNVQMLQSNLQRAKTEMQTLKADLQAT-KALTAKIQGEQNRLGALQEAVAAQKQEQKTQNQVLQLIAQNWKYFNGNFYYFSRDKKPWREAEKFCTSQGAHLASVTSQEEQ----AFLVQTTSSGDHWIGLTDQGTEG-IWRWVDGTPFNNAQSKGFW----GKNQPDNWRHRNGEREDCVHVRQQWNDMACGSSYPWVCKKS----TGWSAARVG----------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8N1N0-1", "uniprot_id": "CLC4F_HUMAN", "id": "Q8N1N0-1", "name": "C-type lectin domain family 4 member F", "aln": "-----MDGEAVRFCTDNQCVSLHPQEVDSVAMAPAAPKIPRLVQATPAFMAVTLVFSLVTLFVVVQQQTRP---VPKPVQAVILGDNITGHLPFEPNNHHHFGREAEMRELIQTFKGHMENSSAWVVEIQMLKCRVDNVNSQLQVLGDHLGNTNADIQMVKGVLKDATTLSLQTQMLRSSLEGTNAEIQRLKEDLEKADALTFQTLNFLKSSLENTSIELHVLSRGLENANSEIQMLNASLETANTQAQLANSSLKNANAEIYVLRGHLDSVNDLRTQNQVLRNSLEGANAEIQGLKENLQNTNALNSQTQAFIKSSFDNTSAEIQFLRGHLERAGDEIHVLKRDLKMVTAQTQKANGRLDQTDTQIQVFKSEMENVNTLNAQIQVLN--GHMKNASREIQTLKQGMKNASALTSQTQMLDSNLQKASAEIQRLRGDLENT-KALTMEIQQEQSRLKTLHVVITSQEQLQRTQSQLLQMVLQGWKFNGGSLYYFSSVKKSWHEAEQFCVSQGAHLASVASKEEQ----AFLVEFTSKVYYWIGLTDRGTEG-SWRWTDGTPFNAAQNK-----------------APGSKGSCPLRKYIIVNSGMG-ACSFIDTPP----CPWILSN------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M6Z340-1", "uniprot_id": "A0A8M6Z340_DANRE", "id": "A0A8M6Z340-1", "name": "", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MDSVYENSRIVLSTVASNENSRNEGNHSYEQESEREVNTAKWNKLLLTVFAVSLVFALGGLCVVSILYVRALTQQ--SAQTNTKIMKRQLEELTANCSRVKDDLYIKDSMMKDLTANYSRVKDDLHIK-DSMVKELTANNSRIKEQQSFYKAFR-------------ASNMTAFQGKLYFFSSDKLTWSSSRAFCVSRGTDLVTITSRSEQ----AFLQSKMN-EWTWIGLSDLETEG-RWVWVNNQTLNDTGVEFWYKRQSGKSEPDNWTKDDPSGEHCAIVKYALN--YLKSWFDVSCEHT----YKFICEKKI----------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8M1RLL2-1", "uniprot_id": "A0A8M1RLL2_DANRE", "id": "A0A8M1RLL2-1", "name": "", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MEAVYEN-----VECRDIKNSTGPQSQNHNRDEENDRKRRRWKCVVLVIMG---LICALLLLFITLQNISITAER--DLFKTYKNTVEELNHTISSLQHDNTDLETDKQQLEDKYNSLSLKKQQLETKYNSLSLGKQQLENRVTSLSAELKEAR-------------------SKSGWFFMSTEAMSWSESRQFCRDRGADLVIIKSEEKQ----RFISSLVK-EDTWIGLSVTETGGNKWKWVDNSPLNQGFWAKGEP-----------NNYQGAKEDCVEVRISQG--TPNNWNDRRCSDS----RKAVCEK------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0AB32TFP3-1", "uniprot_id": "A0AB32TFP3_DANRE", "id": "A0AB32TFP3-1", "name": "", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MTSGIEMAQPIYGNILVNYDPTPKMDRCSLRNETASDSGKKRSSRAAPVCLVLLCLLLLTAVIVLSVFIYTNNTNFAEERRQLITNIANITEDRDKLLTDIINLTKIKDKVLINITNLEEDRDELLNKITTFTKARNEILKKNANLLKDKDQLIKQLQVFG---------------QEAYYQSSFYYLSSERKSWTESRRDCKDRGADLIIINNKQEQ----DFIMKITSNNEFWIGLTDSDKEG-IWKWVDGSNLTSRFWASSGS----------ITEPNGRKTENCAVTHLKKHPELIGWLDVACDGA----YQWICEKNILPVTS-----", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VIX1-1", "uniprot_id": "Q9VIX1_DROME", "id": "Q9VIX1-1", "name": "", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MLKLTVLLITLLVIAKTGWTREKFSIQVN----------EGNTFGALVKAEPFTK-------------------INDGYYFFGTESLNWYEAYEKCRELNSELVTFETDQEFDAVTAFLTANGSRLTYWTSGNDLAKTGSHRWFTNAQRISSLRWARNQP------------DNAGQKEHCIHLGYIYKDSRKFELNDRPCSQDPNSLFKYICEAPEMETISIVVWK", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : . . :::. * .: * . .:.* . . .: *: . * . . . * :.: : ", "identical_positions": 6, "similar_positions": 27, "identity": "0.94%" }, { "cls_id": "homologset.agr.MGI:1859852", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A0G2K6W4-1", "uniprot_id": "A0A0G2K6W4_RAT", "id": "A0A0G2K6W4-1", "name": "Transcription cofactor HES-6", "aln": "MAPPQAPNRDRAGQEDEDRWEARGDRKARKPLVEKKRRARINESLQELRLLLAG-----TEVQAKLENAEVLELTVRRVQGALRGRARGEWRRGSRAGALTGHACHPRAGHVGSRSLGPVHEREQLQAEASERFAAGYIQCMHEVHTFVSTCQAIDAT--VSAELLNHLLESMPLREGSSFRDLLGDSLAGLPGGSGRSSWPPGGSPESPLSSPPGPGDDLCSDLEEIPEAELNRVPAEGPDLVPTSLGILTTARRAQSVWRPW", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9JHE6-1", "uniprot_id": "HES6_MOUSE", "id": "Q9JHE6-1", "name": "Transcription cofactor HES-6", "aln": "MAPSQAPSRDRAGQEDEDRWEARGDRKARKPLVEKKRRARINESLQELRLLLAG-----TEVQAKLENAEVLELTVRRVQGALRGRAR---------------------------------EREQLQAEASERFAAGYIQCMHEVHTFVSTCQAIDAT--VSAELLNHLLESMPLREGSSFQDLLGDSLAGLPGGSGRSSWPPGGSPESPLSSPPGPGDDLCSDLEEIPEAELNRVPAEGPDLVSTSLGSLTAARRAQSVWRPW", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q96HZ4-1", "uniprot_id": "HES6_HUMAN", "id": "Q96HZ4-1", "name": "Transcription cofactor HES-6", "aln": "MAPPAAPGRDRVGREDEDGWETRGDRKARKPLVEKKRRARINESLQELRLLLAG-----AEVQAKLENAEVLELTVRRVQGVLRGRAR---------------------------------EREQLQAEASERFAAGYIQCMHEVHTFVSTCQAIDAT--VAAELLNHLLESMPLREGSSFQDLLGDALAGPPRAPGRSGWPAGGAPGSPIPSPPGPGDDLCSDLEEAPEAELSQAPAEGPDLVPAALGSLTTAQIARSVWRPW", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q01068-1", "uniprot_id": "ESM3_DROME", "id": "Q01068-1", "name": "Enhancer of split m3 protein", "aln": "MVMEMS--------------KTYQYRKVMKPLLERKRRARINKCLDDLKDLMVECLQQEGEHVTRLEKADILELTVDHMR-KLKQRGGLSLQG---------------------VVAGVGSPPTSTSTAHVESFRSGYVHAADQITQVLLQTQQTDEIGRKIMKFLSTRLIELQTQLLQQQQQQQQHQQQQIPQSSGRLAFPLLGGYGPAAAAAAISYSSFLTSKDELIDVTS----VDGNALSETASVSSQESGASEPVWRPW", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*. : :: **. ***:*:*******:.*::*: *:. * ::**:*::***** ::: *: *. . .: * * :**::. .:: .: * * ::*. * .: : .. :: . * ..** .:* *. .. .:.. . ..: :. :* :. .:* * :: : :..*****", "identical_positions": 49, "similar_positions": 75, "identity": "18.56%" }, { "cls_id": "homologset.agr.MGI:1859854", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q5FWT8-1", "uniprot_id": "RCOR2_RAT", "id": "Q5FWT8-1", "name": "REST corepressor 2", "aln": "-------------------------------------MPSVMEKPSAGSGILSRSRAKTAPNGGQPHSEDD---------SSEEEHSHDSMIRVGTNYQAVIPECKPESPARYSNKELKGMLVWSPNHCVSDAKLDKYIAMAKEKHGYNIEQALGMLLWHKHDVEKSLADLANFTPFPDEWTVEDKVLFEQAFGFHGKCFQRIQQMLPDKLIPSLVKYYYSWKKTRSRTSVMDRQARRLGGRKDKEDS-DELEEGR-GAVSEGEPDTGDPKREPLPSRPLNARPGPGK-----KEIQVSQYRHHPLRTRRRPPKGMYLSPEGLTAVSG-SPDLANLTLRGLDSQLISLKRQVQSMKQTNSSLRQALEGGIDPLRPPEANTKFNSRWTTDEQLLAVQAIRRYGKDFGAIAEVIGNKTLTQVKTFFVSYRRRFNLEEVLQEWEAEQDGAPTAPVPVEEARRGAPVPATALEEDDEVQITSVSTSVPRSVPPAP---PPPPPPTSLSQPPPLLRPPLPTAP-TLLRQPPPLQQGRFLQPRLAPNQPPPPLIRPALAASRHS----------ARPGPQPPPTLVGAQLEPPAPSL----------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8C796-1", "uniprot_id": "RCOR2_MOUSE", "id": "Q8C796-1", "name": "REST corepressor 2", "aln": "-------------------------------------MPSVMEKPSAGSGILSRSRAKTAPNGGQPHSEDD---------SSEEEHSHDSMIRVGTNYQAVIPECKPESPARYSNKELKGMLVWSPNHCVSDAKLDKYIAMAKEKHGYNIEQALGMLLWHKHDVEKSLADLANFTPFPDEWTVEDKVLFEQAFGFHGKCFQRIQQMLPDKVIPSLVKYYYSWKKTRSRTSVMDRQARRLGGRKDKEDS-DELEEGR-GAVSEGEPDTGDPKREPLPSRPLNARPGPGK-----KEVQISQYRHHPLRTRRRPPKGMYLSPEGLTAVSG-SPDLANLTLRGLDSQLISLKRQVQSMKQTNSSLRQALEGGIDPLRPPEANTKFNSRWTTDEQLLAVQAIRRYGKDFGAIAEVIGNKTLTQVKTFFVSYRRRFNLEEVLQEWEAEQDGAPAAPVPTEEARRGAPVPATALEEDDEVQITSVSTSVPRSVPPAP---PPPPPPTSLSQPPPLLRPPLPTAP-TLLRQPPPLQQGRFLQPRLAPNQPPPPLIRPALAASRHS----------ARPGPQPPPTLVGAPLEPPAPSL----------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8IZ40-1", "uniprot_id": "RCOR2_HUMAN", "id": "Q8IZ40-1", "name": "REST corepressor 2", "aln": "-------------------------------------MPSVMEKPSAGSGILSRSRAKTVPNGGQPHSEDD---------SSEEEHSHDSMIRVGTNYQAVIPECKPESPARYSNKELKGMLVWSPNHCVSDAKLDKYIAMAKEKHGYNIEQALGMLLWHKHDVEKSLADLANFTPFPDEWTVEDKVLFEQAFGFHGKCFQRIQQMLPDKLIPSLVKYYYSWKKTRSRTSVMDRQARRLGGRKDKEDS-DELEEGR-GGVSEGEPDPADPKREPLPSRPLNARPGPGK-----KEVQVSQYRHHPLRTRRRPPKGMYLSPEGLTAVSG-SPDLANLTLRGLDSQLISLKRQVQSMKQTNSSLRQALEGGIDPLRPPEANTKFNSRWTTDEQLLAVQAIRRYGKDFGAIAEVIGNKTLTQVKTFFVSYRRRFNLEEVLQEWEAEQDGAPGAPVPMEEARRGAPLPAPALEEDDEVQITSVSTSVPRSVPPAP---PPPPPPTSLSQPPPLLRPPLPTAP-TLLRQPPPLQQGRFLQPRLAPNQPPPPLIRPALAAPRHS----------ARPGPQPPPTLIGTPLEPPAPSL----------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6P116-1", "uniprot_id": "RCOR2_DANRE", "id": "Q6P116-1", "name": "REST corepressor 2", "aln": "-----------------------------------------MER--SGSGVLSRSRAKTVTNGNSQHSEEE---------SSDEEHPNDSMIRVGGDYQAQIPEFKPDCASRYGEKDQRSMLVWSPNSQVSDAMLDEYILMAKEKHGYNMEQALGMLLWHKHDVEKSLADLANFTPFPDEWTVEDKVLFEQAFSFHGKSFHRIQQMLPDKMITSLVKYYYSWKKTRTRTSVMDRQARKLLSKREKNESNDEIEEGDPGSDSDFEINAKKESAKQNSGNGGGNEKGPSKSCLTRKENQSAQYRHHPLRARRRPPKGMHLEQEDIVALSA-STDSGAVTIRQLDTQLVSLKRQVQKIKQTNSVLRNNLGDGIEDMRPREPNQKINSRWTTEEQLLAVQAVRRYGKDFAAIADVIGNKTVAQVSSFFVSYRRRFNLEEVLREWQAEQEVQGSSGRTVNTELNGSAELEDDEVKMDGISPPHSDSPLPSSEGSASGNHSSAQSSPPLTQPPPLLRPAPPSAPPSLLRQPPPLQT-RPLQNRTPHNHPPPPLIRPAIASTLHQGALRNSLSSSSSSAGQLPPSLVGLKVESPQSH-----------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q59E36-2", "uniprot_id": "RCOR_DROME", "id": "Q59E36-2", "name": "REST corepressor", "aln": "MVLAERNTTDVVRNGRRSRGPSPNTHTTGGVTNSASLVGSGNNSGHSGNANANEKTTTAVPGAGTPESSDDDNSTKRNGKSKAKQSEYEEKIRVGRDYQAVCPPLVPEAERRPEQMNERALLVWSPTKEIPDLKLEEYISVAKEKYGYNGEQALGMLFWHKHDLERAVMDLANFTPFPDEWTIEDKVLFEQAFQFHGKSFHRIRQMLPDKSIASLVKYYYSWKKTRHRSSAMDRQEKAIKAVVKDGSENGSEVGSNEESDNDDKIQKNRQVMEQLDKECETINVDDVLS----KPAAANTESAQPRISARWLPDEIQVALLAIREYGKNFPTIAKVVATKTEAHVRTFYLNNRRRYNLDQIVKEYEAGKSEESGAEEQTEPAVDAAAAGAATASAPSAADSTSAASATADRK--QSTENSNNGVETMQESLPKKEDPKKPELAAAVLKIGVAEAADAVATVASSTASGVIGAATSASKPSTSATITIIDES---DTATNSSSDVVTTGLATSTGSSALSSTTSAPASKTQTSSEELSAQKSNPASGIAAIGAATGGGQ--------TANSSGSKRDSSVLPVAEQPPAKKIALSTGGGSSVAEFLAN", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : :*.. ... :.:..... .*.:: *. :: :. **** :*** * *:. * : : :.:*****. :.* *::** :****:*** *******:*****:*::: *************:********** ****.*:**:****** *.************* *:*.**** : : . .. .. .. . . .: : : : . . . * :* : * *. : : : . . . :. :::: :: : : : :. ::: . : . * . . :: :. : . .* *: :: : .. . : :. : :* :: : . . . . .:. . : . .. ... .. * .. .:* : *.. : .:*.. : . *: . .. : .::: :.* ", "identical_positions": 112, "similar_positions": 164, "identity": "18.45%" }, { "cls_id": "homologset.agr.MGI:1859866", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q62623-1", "uniprot_id": "CDC20_RAT", "id": "Q62623-1", "name": "Cell division cycle protein 20 homolog", "aln": "-------MAQFVFESDLHSLLQLDAPIPNAPIARWQRKAKEATGPAP---SPMRAANRSHSAGRTPG---------------------------------------------RTPGKSNSKVQTTPSKP------------GGDRYIPQRSASQMEVASFLLSKENQPEDGGTPTKKEHQKAWARNLN------GFDVEEAKILRLSGKPQN---APEGYQNRLKVLYS-QKATPGSSRKACRYIPSLPDRILDAPEIRNDYYLNLVDWSSGNVLAVALDNSVYLWNAGSGDILQLLQMEQPGDYISSVAWIKEGNYLAVGTSNAEVQLWDVQQQKRLRNMTS-HSARVSSLSWNSYILSSGSRSGHIHHHDVRVAEHHVATLSGHSQEVCGLRWAPDGRHLASGGNDNIVNVWPSGPGESGWVPLQTFTQHQGAVKAVAWCPWQSNILATGGGTSDRHIRIWNVCSGACLSAVDVHSQVCSILWSP---------HYKELISGHGFAQNQLVIWKYPTMAKVAELKG-HTARVLSLTMSPDGATVASAAADETLRLWRCFE-----------------------------LDPALRREREKASTSKSSLIHQGIR", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9JJ66-1", "uniprot_id": "CDC20_MOUSE", "id": "Q9JJ66-1", "name": "Cell division cycle protein 20 homolog", "aln": "-------MAQFVFESDLHSLLQLDAPIPNAPVARWQRKAKEATGPAP---SPMRAANRSHSAGRTPG---------------------------------------------RTPGKSSSKVQTTPSKP------------GGDRFIPQRSASQMEVASFLLSKENQPEDRGTPTKKEHQKAWSLNLN------GFDVEEAKILRLSGKPQN---APEGYQNRLKVLYS-QKATPGSSRKTCRYIPSLPDRILDAPEIRNDYYLNLVDWSSGNVLAVALDNSVYLWNAGSGDILQLLQMEQPGDYISSVAWIKEGNYLAVGTSNAEVQLWDVQQQKRLRNMTS-HSARVSSLSWNSYILSSGSRSGHIHHHDVRVAEHHVATLSGHSQEVCGLRWAPDGRHLASGGNDNIVNVWPSGPGESGWAPLQTFTQHQGAVKAVAWCPWQSNILATGGGTSDRHIRIWNVCSGACLSAVDVHSQVCSILWSP---------HYKELISGHGFAQNQLVIWKYPTMAKVAELKG-HTARVLGLTMSPDGATVASAAADETLRLWRCFE-----------------------------MDPALRREREKASVAKSSLIHQGIR", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q12834-1", "uniprot_id": "CDC20_HUMAN", "id": "Q12834-1", "name": "Cell division cycle protein 20 homolog", "aln": "-------MAQFAFESDLHSLLQLDAPIPNAPPARWQRKAKEAAGPAP---SPMRAANRSHSAGRTPG---------------------------------------------RTPGKSSSKVQTTPSKP------------GGDRYIPHRSAAQMEVASFLLSKENQPENSQTPTKKEHQKAWALNLN------GFDVEEAKILRLSGKPQN---APEGYQNRLKVLYS-QKATPGSSRKTCRYIPSLPDRILDAPEIRNDYYLNLVDWSSGNVLAVALDNSVYLWSASSGDILQLLQMEQPGEYISSVAWIKEGNYLAVGTSSAEVQLWDVQQQKRLRNMTS-HSARVGSLSWNSYILSSGSRSGHIHHHDVRVAEHHVATLSGHSQEVCGLRWAPDGRHLASGGNDNLVNVWPSAPGEGGWVPLQTFTQHQGAVKAVAWCPWQSNVLATGGGTSDRHIRIWNVCSGACLSAVDAHSQVCSILWSP---------HYKELISGHGFAQNQLVIWKYPTMAKVAELKG-HTSRVLSLTMSPDGATVASAAADETLRLWRCFE-----------------------------LDPARRREREKASAAKSSLIHQGIR", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A0R4IU39-1", "uniprot_id": "A0A0R4IU39_DANRE", "id": "A0A0R4IU39-1", "name": "", "aln": "-------MSQFGFENDIHNVLRLDMPITNAPMARWQRKASTSNSSSTNSISPNKSVNRSVSLSKTPS---------------------------------------------KTPGK-NGKTQNTPSKA------------GGDRYIPTRNNKQLDVASFLISKENEPVEESEPSTAPNQKAWSMSLN------GYDIEEAKILHLGGKPLY---APEGYQNNLKVLYS-QVPTP-VSVKKSRYISSYPERILDAPDIRNDFYLNLMDWGRQNVLAVGLANQVYLWDAGEGDIVLLKKMEDDNEYICSVSWSKDGNFLAIGTSDCKVELWDVQYQKRLRSMDG-HSARVGCLSWNDHILSSGSRSGLIHQHDVRVADHHIFTFGGHTQEVCGLTWSPDGRYLASGGNDNMVYIWPMTTG-SENQAIHALSEHQGAVKALAWCPWQPNILASGGGTSDRHIRIWNASSGSCISSLDTCSQVSSLVFAP---------NYKELVSGHGFAHDKVVIWKYPSFAKVTEHEG-HEARILNLALSPDGSTLASIAADETIRLWKCFE-----------------------------KEKDAAKKPKQASG---RIVQQSIR", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P26309-1", "uniprot_id": "CDC20_YEAST", "id": "P26309-1", "name": "APC/C activator protein CDC20", "aln": "MPESSRDKGNAAISGNRSVLSIASPTKLNILSSDWSRNQGKVSKNSLKRSSSLNIRNSKRPSLQASANSIYSRPKITIGAPPLIRRDSSFFKDEFDAKKDKATFSAYSSRSYPTIGSESVVSQTSLSQPTTSREVDEQFTVAADRYIPILQGASQNKVDPETLHEALPPPNASPISHLRAQTKIVFKQNVAEACGLDMNKRILQYMPEPPKCSSLRQKSYIMKKRTHYSYQQEQKIPDLIKLRKINTNPERILDAPGFQDDFYLNLLSWSKKNVLAIALDTALYLWNATTGDVSLLTDFEN--TTICSVTWSDDDCHISIGKEDGNTEIWDVETMSLIRTMRSGLGVRIGSLSWLDTLIATGSRSGEIQINDVRIKQHIVSTWAEHTGEVCGLSYKSDGLQLASGGNDNTVMIWDTRTS----LPQFSKKTHTAAVKALSWCPYSPNILASGGGQTDKHIHFWNSITGARVGSINTGSQVSSLHWGQSHTSTNGGMMNKEIVATGGNPENAISVYNYETKFKVAEVVHAHEARICCSQLSPDGTTLATVGGDENLKFYKIFDPRCTGRSREDGLMDGMLGLIGKEGCRTNDKENRSKNSSEIHTRRPSSTSQYLIR", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .: :..: : . . * : *.*: : *. . * . . ::.. * *. . *.: *:. ..**:** . . : .. :* * * . . :: : * *::: : : * :.* . :. ** * . * * : *:****** :::*:****:.*. ****:.* . :***.* **: * .:*: *.**:* .:. .:::*... :.::***: . :*.* . ..*:..*** . ::::***** *: :***: :* : * . *: ***** : .** ******** * :* .. . : . * .****::***:..*:**:*** :*:**::** :*: :.:::. ***.*: :. **::: * ..: : :::* : **:* * :*: :****:*:*: ..**.::::: *: : .. : : : **", "identical_positions": 138, "similar_positions": 173, "identity": "22.4%" }, { "cls_id": "homologset.agr.MGI:1859867", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q925B4-1", "uniprot_id": "SYT8_RAT", "id": "Q925B4-1", "name": "Synaptotagmin-8", "aln": "MQADRSMKMGHVSNPLSTSAPVDATAGPNLIPDLITKIPWPRWILFIAILAAGVLLVSCLLCVICYCCHRQRHRKQPKDKETVGLGSARNSTTTHLVQPDVECLEPCSGGDQPWGQLLLSLEYDFGSQEIRVGLRQAKNLKAE---GTADPYARVSVSTQAGRRHETKVHRGTLCPMFEETCCFLVPPAELPKATLKVQLLDFKRFSEHEPLGELQLPLGTVDLQHVLESWYQLGPPGSTESEQMGELCFSLRYVPSSGRLTVVILEARGLN----PGLAEAYVKVQLILNQRKWKKNKTSSKKGTTNPYFNEAFVFLVPVSQLQSMDLVLAVWARGLQLLAEPVGKVLLGPRASGQPLQHWADMLAHARRPIAQWHHLRSPREVDRALALQPRLPLLRPRS--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9R0N6-1", "uniprot_id": "SYT8_MOUSE", "id": "Q9R0N6-1", "name": "Synaptotagmin-8", "aln": "MQADRSMKMGHALNPFSTSAPLDATAGPSLIPDLITRIPWPRWTLFIAILAAGVLLVSCLLCVICCYCHRHRHRKQPKDKETVGLGSARNSTTTHLVQPDVDCLEPCSGGDQQWGRLLLSLEYDFGSQEIRVGLRQAGNLKAE---GTADPYAWVSVSTQSGRRHETKVHRGTLSPMFEETCCFLVPPAELPKATLKVQLWDFKRFSEHEPLGELQLPLGTVDLQHVLESWYQLGPPGTTEPEQMGELCFSLRYVPSSGSLTVVVLEARGLN----PGLAEAYVKIQLMLNQRKWKKSKTSSKKGTTTPYFNEAFVFLVPVSQLQSVDLVLAVWARGLQLRTEPVGKVLLGSRASGQPLQHWADMLAHARRPIAQWHHLRSPREVDRVLALQPRLPLLRPRS--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8NBV8-4", "uniprot_id": "SYT8_HUMAN", "id": "Q8NBV8-4", "name": "Synaptotagmin-8", "aln": "--------MGHPPVSPSAPAPAGTTAIPGLIPDLVAGTPWPRWALIAGALAAGVLLVSCLLCAACCCCR--RHRKKPRDKESVGLGSARGTTTTHLVQPDVDGLESSPGDAQQWGCLQLSLEFDFGSQEIRVGLRQAADLRPG---GTVDPYARVSVSTQAGHRHETKVHRGTLCPVFDETCCFHIPQAELPGATLQVQLFNFKRFSGHEPLGELRLPLGTVDLQHVLEHWYLLGPPAATQPEQVGELCFSLRYVPSSGRLTVVVLEARGLR----PGLAEPYVKVQLMLNQRKWKKRKTATKKGTAAPYFNEAFTFLVPFSQVQNVDLVLAVWDRSLPLRTEPVGKVHLGARASGQPLQHWADMLAHARRPIAQRHPLRPAREVDRMLALQPRLRLRLPLPHS", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AB13A9P4-1", "uniprot_id": "A0AB13A9P4_DANRE", "id": "A0AB13A9P4-1", "name": "", "aln": "------MTPRPSVKPTKTPHTNTTTAAPGFLPSLLDRIPLPRWAIYAIFAAIVLLILICVICCCVKCCCKGKKKRKKKPDEKINMKGISGTTTTALVQPETEDTEYSS-SDQQRGKLQYSLEFNASRSELTVGIKEAAALKAMDSGGTSDPYVKVYILPNKSKTFETKVFRKTLNPVFNENFKYQIPQKELTESTLVMQVYDFNRFSKHDIIGEIRLNLSTVDWNHVIEEWRDLSEASKHEQEHLGEICFSLRYVPTSSKLTVIILEAKNLKKMDQVGSSDPYVKVQLILEKKKWKKKKTSVKKRTLNPYFNESFTFDVSFEQIQKVQLVISVWDHDKMSRNDAIGKIYLGCDATGNQLRHWADMLSNPRKPVAQWHTLLSAEQVDTTLALKHTLKIPFTNKNF", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . .:. . :** *.::*.*: * *** : * :*:: *::* * ::::: : .*.:.: . .:*** ****:.: * .. . * * * ***:: . .*: **:::* *:. ** ***. * : .: .: .****.* ** *:*:*. : :* **. :** :*: :*:*** *: :**::* *.*** :**:* * *. .. : *::**:********:*. ***::***:.*. * ::.***:**:*:::**** **: ** * *****:*.* *...*:*.::**::** :. :.:**: ** *:*: *:******::.*:*:** * * ...:** ***: * : . ", "identical_positions": 147, "similar_positions": 128, "identity": "36.39%" }, { "cls_id": "homologset.agr.MGI:1859920", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O00559-1", "uniprot_id": "RCAS1_HUMAN", "id": "O00559-1", "name": "Receptor-binding cancer antigen expressed on SiSo cells", "aln": "--MAITQFRLFKFCTCLATVFSFLKRLICRSGRGRKLSGDQITLP----TTVDYSSVPKQTD------------VEEWTSWDEDAPTSVKIEGGNGNVATQQNS--LEQLEPDYFKDMTPTIRKTQKIVIKKREPLNFGIPDGSTGFSSRLAATQDLPFIHQSSELGDLDTWQENTNAWEEEEDAAWQAEEVLRQQKLADREKRAAEQQRKKMEKEAQRLMKKEQNKIGVKLS", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9D0V7-1", "uniprot_id": "RCAS1_MOUSE", "id": "Q9D0V7-1", "name": "Receptor-binding cancer antigen expressed on SiSo cells", "aln": "--MAITQFRLFKVCTCLATVFSFLKRLICRSGRGRKLSGDQITLP----TTVDYSSVPKQTD------------VEEWTSWDEDAPTSVKIEGGNGNVATQQNS--LEQLEPDYFKDMTPTIRKTQKIVIKKREPLNFGVPDGSTGFSSRLAATQDMPFIHQSSELGDLDTWQENSNAWEEEEDAAWQAEEVLRQQKIADREKRAAEQQRKKMEKEAQRLMKKEQNKIGVKLS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q5PQP2-1", "uniprot_id": "RCAS1_RAT", "id": "Q5PQP2-1", "name": "Receptor-binding cancer antigen expressed on SiSo cells", "aln": "--MAITQFRLFKVCTCLATVLSFLKRLICRSGRGRKLSGDQITLP----TTVDYSSVPKQTD------------VEEWTSWDEDAPTSVKIEGGTGNAAAQQNS--LEQLEPDYFKDMTPTIRKTQKIVIKKREPLSFGVPDGSTGFSSRLAATQDMPFIHQSSELGDLDTWQENSNAWEEEEDAAWQAEEVLRQQKIADREKRAAEQQRKKMEKEAQRLLKKEQNKMGVKLS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9VWJ3-1", "uniprot_id": "Q9VWJ3_DROME", "id": "Q9VWJ3-1", "name": "Receptor-binding cancer antigen expressed on SiSo cells", "aln": "MLQQIKMLVLGIITLCRRALCCFSRRRKLSHSGSATGSADQLQAVNVIVERGDFSATGATSAGQAGGGRTAGARERDWNSWDDSPRTVEEHIEQYRQRMAQPPTPPKEEPEPDFFSELTPTIKPQMKFYLE--DPSTSAATSQQSDFS-RLQAQDLVPISVN----ADLEDWVDDN-------AGGWEELDTSQTKHILREKRRELRHQRQPPVRPAPPTVGAQRLTAGQRAA", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *. : * . * :: .* :* . . . *.**: *:*:. : .:*.***:.. * : : :* : *: ***:*.::****: *: :: :* . . .. .:.** ** * : :*: : .**: * ::. ..*: :. : ::: .::* .:**: : * : :: . * : :", "identical_positions": 42, "similar_positions": 74, "identity": "18.03%" }, { "cls_id": "homologset.agr.MGI:1859937", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9JHI4-1", "uniprot_id": "S13A1_MOUSE", "id": "Q9JHI4-1", "name": "Solute carrier family 13 member 1", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MKLLNYALVYRRFLLVVFTILVFLPLPLIIRTKEAQCAYILFVIAIFWITEALPLSITALLPGLMFPMFGIMR----------------------------------------------------------------------SSQVASAYFKDFHLLLIGVICLATSIEKWN------------------------LHKRIALRMVMMVGVNPAWLTLGFMSSTAFLS----MWLSNTSTAAMVMPIVEAVAQQIISA------EAEAEATQMTYFNESAAHGLDIDETVIGQETNEKKEKTKPAPGSSHDKGKVSRKMETEKNAV--TGAKYRSRKDHMMCKLMCLSVAYSSTIGGLTTITGTSTNLIFSEHFNTRYPDCR-CLNFGSWFLFSFPVALILLLLSWIWLQWLYLGFDFK-MFKCGKTKTLKE----------KACAKVIKQEYEKLGPMRYQEIVTLVIFIVMALLWFSRDPGFVTGWSVLFSEYPGYVTDSTVALVAGILFFLIPAKKVTKMTS-AGEIIAFDYT-------------------PLITWKEFQSFMPWDIAILVGGGFALADGCQVSGLSNWIGSKLSPLG-SLPVWLIILISSLIVTSLTEVASNPATITILFPILSPLAEAIQVN--PLQILLPSTLCTSFAFLLPVANPPNAIVFSYGHLKVIDMVKAGLGVNILGVAVVMLGMFTWIEPMFN-LHEYPSWASNFVNQTMP", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q07782-1", "uniprot_id": "S13A1_RAT", "id": "Q07782-1", "name": "Solute carrier family 13 member 1", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MKLLNYAFVYRRFLLVVFTVLVLLPLPLIIRSKEAECAYILFVIATFWITEALPLSITALLPGLMFPMFGIMS----------------------------------------------------------------------STHVASAYFKDFHLLLIGVICLATSIEKWN------------------------LHKRIALRMVMMVGVNPAWLTLGFMSSTAFLS----MWLSNTSTAAMVMPIVEAVAQQITSA------EAEAEATQMTYFNESAAQGLEVDETIIGQETNERKEKTKPALGSSNDKGKVSSKMETEKNTV--TGAKYRSKKDHMMCKLMCLCIAYSSTIGGLTTITGTSTNLIFSEHFNTRYPDCR-CLNFGSWFLFSFPVAVILLLLSWIWLQWLFLGFNFKEMFKCGKTKTLKE----------KACAEVIKQEYEKLGPMRYQEIVTLVIFIVMALLWFSRDPGFVTGWSVLFSEYPGYVTDSTVALVAGILFFLIPAKKLTKMTS-TGDIIAFDYS-------------------PLITWKEFQSFMPWDIAILVGGGFALADGCQVSGLSSWIGSKLSPLG-SLPVWLIILISSLIVTSLTEVASNPATITILFPILSPLAEAIHVN--PLHILLPSTLCTSFAFLLPVANPPNAIVFSYGHLKVIDMVKAGLGVNILGVAVVMLGMFTWIEPMFN-LHEYPSWAPDIVNQTMP", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9BZW2-1", "uniprot_id": "S13A1_HUMAN", "id": "Q9BZW2-1", "name": "Solute carrier family 13 member 1", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MKFFSYILVYRRFLFVVFTVLVLLPLPIVLHTKEAECAYTLFVVATFWLTEALPLSVTALLPSLMLPMFGIMP----------------------------------------------------------------------SKKVASAYFKDFHLLLIGVICLATSIEKWN------------------------LHKRIALKMVMMVGVNPAWLTLGFMSSTAFLS----MWLSNTSTAAMVMPIAEAVVQQIINA------EAEVEATQMTYFNGSTNHGLEIDESVNGHEINERKEKTKPVPGYNNDTGKISSKVELEKNSG--MRTKYRTKKGHVTRKLTCLCIAYSSTIGGLTTITGTSTNLIFAEYFNTRYPDCR-CLNFGSWFTFSFPAALIILLLSWIWLQWLFLGFNFKEMFKCGKTKTVQQ----------KACAEVIKQEYQKLGPIRYQEIVTLVLFIIMALLWFSRDPGFVPGWSALFSEYPGFATDSTVALLIGLLFFLIPAKTLTKTTP-TGEIVAFDYS-------------------PLITWKEFQSFMPWDIAILVGGGFALADGCEESGLSKWIGNKLSPLG-SLPAWLIILISSLMVTSLTEVASNPATITLFLPILSPLAEAIHVN--PLYILIPSTLCTSFAFLLPVANPPNAIVFSYGHLKVIDMVKAGLGVNIVGVAVVMLGICTWIVPMFD-LYTYPSWAPAMSNETMP", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AB32TJ70-1", "uniprot_id": "A0AB32TJ70_DANRE", "id": "A0AB32TJ70-1", "name": "", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MRRLRCSWSALKPLIIISTPLAILPLPLVIKTKEAECAYVLILMAVYWMTEVLPLSVTALIPALLFPLFGIMK----------------------------------------------------------------------SSQVASQYFKDFHLLLLGVICLATSIEKWG------------------------LHRRIALRLVTGLGVNPGMLMLGFMVGCAFLS----MWLSNTSTVAMVMPIVEAVIQQVLSA------SEEANKDHKGALNGISNPALQLEDIEAQHDQSE---KIKSIEAGITEPEPTSEEHETAKAPTPPYSGKYRTREDHMMCKGLSLCIAYSSSIGGLTTLSGTSTNLIFAEYIYQYYPECT-IVNFGNWFVLCLPICIIMLILSWLFLHWMYLGSNFR-ASLCSRQRTEKE----------KITARVLRDHYNSLGPISWQEIVTLIIFILMAILWFTRNPGFMPGWSSLFSDNPGYATDATVALLLGFLFFLLPSHKLNADHYGTTTLKTFSMIGGALSAFLLMIYIFIHLTEALITWKDFQACMPWEISLLVGGGFALAEGTKISGLSSWVAELLTPLG-SLPPLATVTIACLIVTSITEVASNAATMTIFLPILAPLAEAIGVN--PLYMLIPTALAVSFSFLLPVSNPPNAIVFTYGHLTSMDMVKAGLGVNVIGILTVLLALTTWGTPLLK-LDTYPDWAPVVNSTGV-", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "E1JIQ7-1", "uniprot_id": "E1JIQ7_DROME", "id": "E1JIQ7-1", "name": "Protein I'm not dead yet 2", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MGDADGKIGGGQAVKRCCGFHWRGKATAMIPLITLPIMIYGVLENNLAFQCMYLVANMALFWITEAIPLYLTALFPVVFLPLFGILT----------------------------------------------------------------------SEKVCSFYFSDTVVMFIGGLLIALAIEYSN------------------------LHQRIALNTILIVGCSPRRLHFGLVMVTCFIS----LWISNSAATAMMCPIVKAVLN-----------EMETQNIFAIYKTQEEEPVEEGDPPHPST-----------------------------------------------ISMAFYFGIAYSSSIGGCGTLIGTGTNLTYKGLYDTRFPNSDEKIDFPIFMAYSVPFVVLVLIFLTYFSLQVTHMGLFRPNSKIGQEVKKGAE-------SQDVVKDVIKQRKAELGPMSCHEIQVGLLFVLMIFLLFTRKPGFFPGWADFLN-AKAIGSGPPVFFATILLFALPTQYTFFKYCCGKAPFPGQTLD-------------------ACLSWVYCQKYTPFGLAFLLGGGFALAEGSRVSGMAKMLGESLAFAG-EMHSVLVISMCIIISLFCTAFASNVAICNILIPIFSEMALAIEVH--PMKLTFPAALACSLAFHLPVSTPPNAIISGFTGLKTKYMAIAGILPTCWAFLCLLFTGTVWTMLIYPGTTEFPSWAI--------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VDQ0-1", "uniprot_id": "INDY2_DROME", "id": "Q9VDQ0-1", "name": "Protein I'm not dead yet 2", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MAEPGEQR--KFVLGRCCIFHWRGKASIIIPLITLPILIYGFQTDMAEFKCLWLIVTMALLWITETLPIYVTALFPLVFCPLLGLVN----------------------------------------------------------------------ASIVCKQYFTDTIVVFLGGLIVALGIEYSN------------------------LHTRIALRVIRIVGGSPRRLFVGLMSVSTFMG----LWISNSAGTAMMCPIVKALVN-----------ELDTNKIFPVYMTQEEEPVEEGEPPHPSK-----------------------------------------------ITVAFYAGIAYASSIGGLGTLIGTGTNLVFRGIYTERFPTSTVEITFANFMFYSIPLMVIVNVTLVIIAFLITHMGLFRPNSKTGKIIAEANT-------NRKLMEDVLRQRHIDLGPMSCHEIQMAIAFAFMIVLLITRKPGFVPGWSDLIN-RKVVGSASGLSFIVLLIFALPTQYTFFKYCCGKGPFTAQAID-------------------AILSWEYVLRNIPWGLLFLLGGGFALAVASRETGLNIMISKAMQVLI-GLPNIVVQSITFVLANFFSAFNANVVVANIVLPILCEMSLALELH--PLILTLPACLGISMVYFLPVSTPPNAIVTQYAHIKTKYFACCGIVPTIIGISVALVNTNTWGLIIFPESKSFPDWAKEIKNQTKI", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P39535-1", "uniprot_id": "PHO90_YEAST", "id": "P39535-1", "name": "Low-affinity phosphate transporter PHO90", "aln": "MRFSHFLKYNAVPEWQNHYMDYSELKNLIYTLQTDELQ-------------------VGDNEEGFGAGKSSNITDRFKNKFSFKNAKEDTSSGMNKDAG---------IVEETIELRELPTAQTVAAKPSPFRRMKEKIFYKRRSSSASSVSSTANENLQLDTYDTFVGDLTAEKQKVDDFYKRTEAKFYDKFDALVKDLKKIGVIE-------YDIDDDTLFNEPIASTND--------EVPPLDLD-----------DDEDDDEFYDDQSNIEDNTALLHHSQYNIKSQKKSLLKKSIVNLYIDLCQLKSFIELNRIGFAKITKKSDKVLHLNTRTELIESEQFFKDTYAFQAETIELLNSKISQLVTFYARITD---RPHN-------------------------------ISHSKQELKSYLHDHIVWERSNTWKDMLGLLSQADELTPKETEYNAN---------KLVGKLDLEYYRWPLPRPINLKFTSINNVALPK---LFFTKKAYKIYFIILVTGLLLGIKTFN------DAAQHRCMALVECVAFLWASEAIPLHITAFLVPLLVVLFKVLKT-SDGAIMSAASASSEILA-------AMWSSTIMILLAGFTLGEVLAQYNIAKVLASWLLAFAGCKPRNVLLMAMCVVFFLSMWISNVAAPVLTYSLLSPLLDAMDADSPFAQALVLGVALAANIGGMSSPISSPQNIISMSYLKPYGIGWGQFFAVALPSGILAMLLVWILLFTTFKMN-KTKLEKFKPIKTKFTVKQYYIITVTVATILLWCVESQIEGAFGSSGQIAIIPIVLFFG---------TGLLSTQDLNAFPWSIVILAMGGIALGKAVSSSGLLSTIAKALQKKIENDGVFAILCIFGILMLVVGTFVSHTVSAIIIIPLVQEVGDKLGNPKAAPILVFGCALLSSCGMGLASSGFPNVTAISKVDRKGDRYLSVMTFLTR-GVPASILAFLCVITLGYGIMASVVKGNATSA-----", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P25360-1", "uniprot_id": "PHO87_YEAST", "id": "P25360-1", "name": "Inorganic phosphate transporter PHO87", "aln": "MRFSHFLKYNAVPEWQNHYLDYNELKNLIYTLQTDELKQETPTGDLNDDADSQTPGPIADIESNIAAGEPSSSKRRFTHKLKRKLFGSKTPSGSKRGDSDEKAIDGNNINEETIELDELSPQGKTTSFNKNFIR---KKFFESRSSSVSSEGKTL-----FSSYDTFVTNLSDEKLKVDDFYKRMEAKFYERFDHLINDLEKEGIVTRLNETFNPEIQALPPLREIISGTSETHSSNNPFEIHSSNIDSELRNRFDYSEEEMDEDDDVDVFADTTDNTALLNYSQFNIKSQKKSLLKQTIINLYIDLCQLKSFIELNRMGFSKITKKSDKVLHMNTRQELIESEEFFKDTYIFQHETLSSLNSKIAQLIEFYAVLMG---QPGN-------------------------------VDSCKQELKSYLHDHIVWERSNTWKDMLGLSSQNNDIITIEDEAEK----------LMQEKLQIEYFKYPLPKPINLKFTKIENLAVPK---LFFGKRAMKIGFIIIVTGVLLGVKTFN------DPVEHRCMALVECCAFLWASEAIPLHITGLLVPLLTVLFRVLKD-DDGKVMGAAAASTEILG-------TMWSSTIMILLAGFTLGEALSQYNVAKVLASWLLALAGTKPRNVLLMAMSVVFFLSMWISNVASPVLTYSLLTPLLDPLDYTSPFAKALVMGVALSADIGGMASPISSPQNIISMQYLKPYGIGWGQFFAVALPTGILSMLCSWALMILTFKIG-KTKLEKFKPIRTRFTIKQYFIIIVTIATILLWCVESQIESAFGSSGEIAVIPIVLFFG---------TGLLSTKDFNTFPWSIVVLAMGGIALGKAVSSSGLLVTIARALQKKIQNDGVFAILCIFGILMLVVGTFVSHTVSAIIIIPLVQEVGDKLSDPKAAPILVFGCALLASCGMGLASSGFPNVTAISMTDKKGNRWLTVGAFISR-GVPASLLAFVCVITLGYGISSSVLKGST--------", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P27514-1", "uniprot_id": "PHO91_YEAST", "id": "P27514-1", "name": "Low-affinity phosphate transporter PHO91", "aln": "MKFSHSLQFNSVPEWSTKYLAYSQLKKLIYSLQKDKLY--------------------SNNKHHVVEPHDANDEN---LPLLADASPDDQFYISKFVAA---------LNQELKKIDKFYISQETGLIAN----------YNELKDDVMELENTN------KATQLFNQQQQHQLQSVARNRKSKSQQRQRRFSSVSSTDSNPSLTD-------MSIDSAPVIHTQVSNTTN----------------------------NGNSMQNLASASVSLSNSNPVYLSPF---TQHRLSLKKRLISIYTQLSELKDFIELNQTGFSKICKKFDKSLNTNLKQNYLNYIKFHS--HVFNPATINRIQHHITETILTYASLNKGTRRPSNTFNLDADRINNDENSSGNEEDEDGNRQEVLDFQDAERELSSHLRDHVVWERNTVWKDMMNLERKYQSAKTDNKKFSKLSSSQLRPNANITESMAMSSGGAGIIAPSTDSLTFRELMHLPPKQWLQFIMGQTSLLKFLLITSCFIALLTFNLTPFTQDSLQKNCFAILIYASLLWATETIPLFVTSLMIPLLIVVFPVIKDPITSQPMSPRDSSQFILS-------TMWSSVIMLLLGGFTLAAALSKYNIAKVLSTHILASAGTNPHFILLTNMFVALFVSMWVSNVAAPVLCYSIVQPLLRTLPRNCSYAKALILGIALASNIGGMSSPIASPQNIFSIGIMDPS-PSWAEWFMIALPVCFICVMAIWVLLIITFPPEPNVKILQLHPSRDPFTLKQWFVTLVCIITIVLWCLSNQISGIFGEMGIISIIPIVVFFG---------TGLLTSDDFNNFMWTIVVLAMGGTTLGKAVSSSGLLSTMAQLIKAQVEHEPIFIIVLIFGLVILVMATFVSHTVAAMIIVPLMSEIGSNLPSGDHSRLLIVIAALLCSSAMGLPTSGFPNVTAISMIDEVGDRYLTVGTFITR-GVPASLLSYAAIVTVGYGILKVMGF-----------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . * . : : . : : : : . . :: * : . : : : * . . : . :. . . . : :. : . .: .: * .. :: : : . . : . : : : * : : . : . : . : : : .* ** :*. . :*: :. : : :: . :: . :..*:. :. : . : . * * *. : **. . .. :. ", "identical_positions": 16, "similar_positions": 94, "identity": "1.58%" }, { "cls_id": "homologset.agr.MGI:1859980", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I6GJX9-1", "uniprot_id": "A0A8I6GJX9_RAT", "id": "A0A8I6GJX9-1", "name": "Insulinoma-associated protein 1", "aln": "MDGPIWRLRAPRRRHTKPRHVRLPIEEQQTVKGGGAGRVPGPGGAAAPGAAGRGGRGARAGAPRPQVHLPHLPGDPRVPAPFLPLCRPPALVGGGAADALIGSGGSGRREQWPPPPVKRERRPGPGTGTRVRSAEPGQQPRAPRESRSRRVQPVRRRPLHRANMPRGFLVKRSKKSTPVSYRVRGGEDCDRALLLSPGC---------------GGARAEPPVPS--PGPLPPPPPPALAERAHAALAAALACAPGPPPPPP-GPRAAHFGNPEAAHPAPLYSPTRPVSREHEKHKYFERSFNLGSPVSAESFP------TPAALLAGGGGGANGAGGGGGGTCGGDALLFAPAELKMG---TAFSAGAEAARGPGPGPPLSPAAALRPPGKRPAAPAAVAAEPPAKAAKAPSAKKPKAIRKLHFEDEVTTSPVLG-----------LKIKEG---------PVEA-PRGRAGGATRPLGEFICQLCKEEYADPFALAQHKCSRIVRVEYRCPECAKVFSCPANLASHRRWHKPRPAPAAARAPEPEAATRAEAREAAGGGGSSDRDTPSPGGVSESGSEDGLYECHHCAKKFRRQAYLRKHLLAHHQALQAKGAPPPPPPPPPPPAEDILAFYAGPDEKAPQEASGDGEAVGVLGLSAATECHLCPVCGETFPS-----------------------------------KGAQERHLRLLHA-AQVFPCKYCPATFYSSPGLTRHINKCHPSENRQ-VILLQVPVRPAC---------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q63ZV0-1", "uniprot_id": "INSM1_MOUSE", "id": "Q63ZV0-1", "name": "Insulinoma-associated protein 1", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------MPRGFLVKRSKKSTPVSYRVRGGEDSDRALLLSPGC---------------GGARAEPPVPS--PGPLPPPPPPALAERAHAALAAALACAPGPPPPPPPGPRAAHFGNPEAAHPAPLYSPTRPVSREHEKHKYFERSFNLGSPVSAESFP------TPAALLAGGGSGANGAGGGGGGTCGGDALLFAPAELKMG---TAFSAGAEAARGPGTGPPLSPAAALRPPGKRPAPPAAVATEPPAKAAKAPSAKKPKAIRKLHFEDEVTTSPVLG-----------LKIKEG---------PVEA-PRGRAGGATRPLGEFICQLCKEEYADPFALAQHKCSRIVRVEYRCPECAKVFSCPANLASHRRWHKPRPVPAAARAPEPEAATRAEAREAAGGG-SSDRDTPSPGGVSESGSEDGLYECHHCAKKFRRQAYLRKHLLAHHQALQAKGAPPPPPPPPPP-AEDILAFYAGPDEKAPQEASGDGEAAGVLGLSATAQCHLCPVCGETFPS-----------------------------------KGAQERHLRLLHA-AQVFPCKYCPATFYSSPGLTRHINKCHPSENRQ-VILLQVPVRPAC---------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q01101-1", "uniprot_id": "INSM1_HUMAN", "id": "Q01101-1", "name": "Insulinoma-associated protein 1", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------MPRGFLVKRSKKSTPVSYRVRGGEDGDRALLLSPSC---------------GGARAEPPAPSPVPGPLPPPPP---AERAHAALAAALACAPGPQPPPQ-GPRAAHFGNPEAAHPAPLYSPTRPVSREHEKHKYFERSFNLGSPVSAESFP------TPAALLGGGGGGG-ASGAGGGGTCGGDPLLFAPAELKMG---TAFSAGAEAARGPGPGPPLPPAAALRPPGKRPPPP--TAAEPPAKAVKAPGAKKPKAIRKLHFEDEVTTSPVLG-----------LKIKEG---------PVEA-PRGRAGGAARPLGEFICQLCKEEYADPFALAQHKCSRIVRVEYRCPECAKVFSCPANLASHRRWHKPRPAPAAARAPEPEAAARAEAREAPGGG--SDRDTPSPGGVSESGSEDGLYECHHCAKKFRRQAYLRKHLLAHHQALQAKGAPLAPP------AEDLLALYPGPDEKAPQEAAGDGEGAGVLGLSASAECHLCPVCGESFAS-----------------------------------KGAQERHLRLLHA-AQVFPCKYCPATFYSSPGLTRHINKCHPSENRQ-VILLQVPVRPAC---------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q7T3H2-1", "uniprot_id": "INS1B_DANRE", "id": "Q7T3H2-1", "name": "Insulinoma-associated protein 1b", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------MPKGFLVKRNKKAALVSYRIRTDEDGGPTPECPI-----------------AQIALSSPAPS-----------------ASKPDSILLAFPSAGAEAPVPVHKPVQFGNPEAVYQA-LYSPTRPVSKDHDR-KYFERSLNLGSPISAESFP------TPASLTSLD-----------------HHLLFAPVDLKIG---TSNSN--RSGTASGAHAPAIQTGAKRP-----------SADAAERKVSSKSAKKPKAIRKLNFEDEVTTSPVLG-----------LKIKEG---------PVDLKPRPSSGGTNKPLGEFICQLCKEEYSDPFSLAQHKCSRIVRVEYRCPECEKVFSCPANLASHRRWHKPRVQSAPKQALQPAKPFPEELRAEFPSD----RDTPSPG-LSESGSEDGLYDCQHCGKRFKRQAYLRKHILGHQALQNQI-----------------LGEAFRSAESPDAMPSEDRQSPAPLNLSP-ADCLTCPACGEKLPN-----------------------------------RASLERHLRLLHDDAQAFPCKFCPATFYSSPGLTRHINKCHPTENRQ-VILLQMPVRNAC---------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q6P0F9-1", "uniprot_id": "INS1A_DANRE", "id": "Q6P0F9-1", "name": "Insulinoma-associated protein 1a", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------MPRGFLVKRNKKATPVSYRVRSEEDE-------------------------QGAFVAQDVPC-----------------ARRP------------------VSPVQFGNPETVYRA-MYSPTRPVSREHER-ACLERRFNLGSPISAESFP------AAPNCSDQ-----------------------APVDLKIG---TSNSN--RTGTTVTTKRPASDT---------------------ERKGKP-ASKKAKAMRKLQFEDEMTTSPVLG-----------LKIKEG---------PVEQKPRSQCASGDKPLGEFVCQLCREAYADPFSLAQHKCSRIVRIEYRCPECDKLFSCPANLASHRRWHKPKQSAESNKTPAPEK-------EETSSD----RDTPSPG-LSESGSEDGLYDCQHCGKKFKRQAYLKKHVTAHHDAP------------------------------------EKPQSHAPLNLSA-SECHLCPVCGENFPS-----------------------------------RMSQERHIRLQHS-AQVYPCKYCPAMFYSSPGLTRHINKCHPSENRQ-VILLQMPVRPAC---------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A0B4KH20-1", "uniprot_id": "A0A0B4KH20_DROME", "id": "A0A0B4KH20-1", "name": "", "aln": "--------------------------MMNMNPPTHPHPHHHPHPHPHPQPQSHLQSVQHLGQHQPLPALLQGHPDTTHFVECRALPAINETFPQFGQHRPAISLLSPLDLSLRAAASVVPITPPSTPSPPRKRQRLMSEENYLWRPHMASPAAPAPVVPSSLAMQPGYFHHHQQQQHQLPHQQHHQPYATRSSLEGASFNKSHFHGTKNNFEQIPAGQSSVSSPIYVEDETIVLTEDEDETVVSSHDYNEYATDTEEVNEGDDETQQVQVSVNGDDDEEEVFVDVLGSDDDEDEATDLVATRLQAQLIETTALKRNELLYEDEELHNQAVNGLARLFDRDFPEPDVEVSGLAELQSNSGKTYTDLSGVATAEIRTTSSDNLPPPPPPPPPPATSTIPATPPLPPPPISRPHKAERRRSKLRKHMAIDEETISPVSGTIIRKLRDDEELVVRKGDIDPAFNVVEITEEAKAILASIDNKIGDYMCQLCRTVYDDAFMLAQHRCPRIVHIEYKCSECEKVFNCPANLASHRRWHKPKAEAAGVNPAKKRVVETGDLVQEATRS--------------GDDASDGIYPCHICGKTFRRQAYLKKHQASHQMLDNLKNLDFFKSQQQQLTINGHQLADHVQLQHTTGQAVTSAAPYASLPRPPPGMPMYPPPSGKNYPGGQRFPGFPFQSFDQRRFYSLGEFYLSQHLERSSAFQYVQANHLRQLSNVAQTLMPPLPVKXPNPNTNVLRPVPRIAATATATGPPAAATATRQAATAAGVSSVGHAFNWVAPSTAGATATGSATATATATTAESGGNVIM", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9V3B8-1", "uniprot_id": "Q9V3B8_DROME", "id": "Q9V3B8-1", "name": "", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------MAQIQTPIPIPAPAEPIEKLSHPHSIGIQLQHKGMPHGLGLLTTVASLPP-------------KYRSRYLNLKTRC----------------EIPLDLTLKLPSPLPSSDVPMAATFAEVYSENTSASSSEVQGEVTKVEELPVKPPTPPQSPAGKRKLSRESYDD-----EPAKMAKKEEE--------------------VPVETVES---TPAKPVKVAESAPKTNKASTSSGKPSRN---------KATRKLKFDEETSSPVSGTVIRPLEDITDGSMQYSNG----------DIDPKYN-------IVEITEETKAELAAIKNVIGDYVCRLCKIKFEDAFGLARHRCACIVLLEYRCPECGKQFNCPANLASHRRWHKPRKEASKKENRNTTNQPEKQQQVEKKSE------------------EELAFDCQECGKKFKRAAYLRKHQLTHQKKEK-------------------------PAEKQLEMKPTTTTITGSFHFNQAVSTSSSASSSHSDEG-----------------------------------VYVVGSNARENYDYDNDYLSDSSSSASSAGYGRLQIVEHG-LTEEESIAAAALTNLRNCASVIQHTTMAH-----------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : . : :: . : . . . :. : . : . * . : . . . . :* : : . * : : . : .: .. . :*:::*:**: : *.* **:*:*. ** :**:*.** * *.**************: . . .: : *: *.* *:* ***:** *: . : . .... . : * : .. . : : : : * .. ", "identical_positions": 49, "similar_positions": 81, "identity": "6.01%" }, { "cls_id": "homologset.agr.MGI:1859993", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O54835-1", "uniprot_id": "SMAD9_RAT", "id": "O54835-1", "name": "SMAD family member 9", "aln": "-----MHPSTP-----ISSLFSFTSPAVKRLLGWKQGDEEEKWAEKAVDSLVKKLKKKKGAMDELERALSCPGQPSKCVTIPRSLDGRLQVSHRKGLPHVIYCRVWRWPDLQSHHELKPLECCEFPFGSKQKEVCINPYHYRRVETPVLPPVLVPRHSEYNPQLSLLAKFRSASLHSEPLMPHNATYPDS-FQQSLGPAPPSSPGHVFPQSPCPTS-YPQSPGSPSESDSPYQHS-------------------------------------DFRPVCYEEPLHWCSVAYYELNNRVGETFQASSRSVLIDGFTDPSNNRNRFCLGLLSNVNRNSTIENTRRHIGKGVHLYYVGGEVYAECVSDSSIFVQSRNCNYQHGFHPATVCKIPSGCSLKVFNNQLFAQLLAQLLAQSVHHGFEVVYELTKMCTIRMSFVKGWGAEYHRQDVTSTPCWIEIHLHGPLQWLDKVLTQMGSPHNPISSVS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9JIW5-1", "uniprot_id": "SMAD9_MOUSE", "id": "Q9JIW5-1", "name": "SMAD family member 9", "aln": "-----MHPSTP-----ISSLFSFTSPAVKRLLGWKQGDEEEKWAEKAVDSLVKKLKKKKGAMDELERALSCPGQPSKCVTIPRSLDGRLQVSHRKGLPHVIYCRVWRWPDLQSHHELKPLECCEFPFGSKQKEVCINPYHYRRVETPVLPPVLVPRHSEYNPQLSLLAKFRSASLHSEPLMPHNATYPDS-FQQSLCPAPPSSPGHVFPQSPCPTS-YPHSPGSPSESDSPYQHS-------------------------------------DFRPVCYEEPQHWCSVAYYELNNRVGETFQASSRSVLIDGFTDPSNNRNRFCLGLLSNVNRNSTIENTRRHIGKGVHLYYVGGEVYAECVSDSSIFVQSRNCNYQHGFHPATVCKIPSGCSLKVFNNQLFAQLLA----QSVHHGFEVVYELTKMCTIRMSFVKGWGAEYHRQDVTSTPCWIEIHLHGPLQWLDKVLTQMGSPHNPISSVS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O15198-1", "uniprot_id": "SMAD9_HUMAN", "id": "O15198-1", "name": "SMAD family member 9", "aln": "-----MHSTTP-----ISSLFSFTSPAVKRLLGWKQGDEEEKWAEKAVDSLVKKLKKKKGAMDELERALSCPGQPSKCVTIPRSLDGRLQVSHRKGLPHVIYCRVWRWPDLQSHHELKPLECCEFPFGSKQKEVCINPYHYRRVETPVLPPVLVPRHSEYNPQLSLLAKFRSASLHSEPLMPHNATYPDS-FQQPPCSALPPSPSHAFSQSPCTAS-YPHSPGSPSEPESPYQHSVDTPPLPYHATEASETQSGQPVDATADRHVVLSIPNGDFRPVCYEEPQHWCSVAYYELNNRVGETFQASSRSVLIDGFTDPSNNRNRFCLGLLSNVNRNSTIENTRRHIGKGVHLYYVGGEVYAECVSDSSIFVQSRNCNYQHGFHPATVCKIPSGCSLKVFNNQLFAQLLA----QSVHHGFEVVYELTKMCTIRMSFVKGWGAEYHRQDVTSTPCWIEIHLHGPLQWLDKVLTQMGSPHNPISSVS", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F1QXZ9-1", "uniprot_id": "F1QXZ9_DANRE", "id": "F1QXZ9-1", "name": "Mothers against decapentaplegic homolog", "aln": "-----MHSSTS-----ITSLFSFTSPAVKRLLGWKQGDEEEKWAEKAVDSLVKKLKKKKGAMEELEKALSCPGQPSKCVTIPRSLDGRLQVSHRKGLPHVIYCRVWRWPDLQSHHELKALDCCEFPFGSKQKEICINPYHYRRVETPVLPPVLVPRHSEFNPQHSLLAKFRNASLHNEPLMPQNATFPDS-FPAMPCSSFSSSPSSSLNPSPAAHS-FPNSPSSATEPGSPYQITAETPPPPYSMMESSPSEDVKPAESSENK-LILTAPQRDLRPVCYEEPEYWCSVAYYELNNRVGETFHASARSILVDGFTDPSNNKNRFCLGLLSNVNRNSTIEHTRRHIGKGVHLYYVGGEVYAECLSDSSIFVQSRNCNYQHGFHPTTVCKIPSGCSLKIFNNQLFAQLLS----QSVNHGFEVVYELTKMCTIRMSFVKGWGAEYHRQDVTSTPCWIEIHLHGPLQWLDKVLTQMGSPHNPISSVS", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P42003-1", "uniprot_id": "MAD_DROME", "id": "P42003-1", "name": "Protein mothers against dpp", "aln": "MDTDDVESNTSSAMSTLGSLFSFTSPAVKKLLGWKQGDEEEKWAEKAVDSLVKKLKKRKGAIEELERALSCPGQPSKCVTIPRSLDGRLQVSHRKGLPHVIYCRVWRWPDLQSHHELKPLELCQYPFSAKQKEVCINPYHYKRVESPVLPPVLVPRHSEFAPGHSMLQFNHVA----EPSMPHNVSYSNSGFNSHSLSTSNTSVGSPSSVNSNPNSPYDSLAGTPPPAYSPSEDGNSNNP--------------------NDGGQLLDAQMGDVAQVSYSEPAFWASIAYYELNCRVGEVFHCNNNSVIVDGFTNPSNNSDRCCLGQLSNVNRNSTIENTRRHIGKGVHLYYVTGEVYAECLSDSAIFVQSRNCNYHHGFHPSTVCKIPPGCSLKIFNNQEFAQLLS----QSVNNGFEAVYELTKMCTIRMSFVKGWGAEYHRQDVTSTPCWIEIHLHGPLQWLDKVLTQMGSPHNAISSVS", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :...*. : ***********:***************************:***::***:***************************************************.*: *::**.:****:*******:***:*************: * *:* : * ** **:*.::.:* * .: .* . .. . * : ..:.. . ** : *. *.*.** .*.*:****** ****.*:.. .*:::****:**** :* *** ***********:************** *******:***:**********:*****:******.*****:**** *****: ***::***.*********************************************************.*****", "identical_positions": 311, "similar_positions": 72, "identity": "64.39%" }, { "cls_id": "homologset.agr.MGI:1860040", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O70277-1", "uniprot_id": "TRIM3_RAT", "id": "O70277-1", "name": "Tripartite motif-containing protein 3", "aln": "----MAKRE-DSPGPEVQPMDKQFLVCSICLDRYRCPKVLPCLHTFCER-CLQNYIPPQSLTLSCPVCRQTSILPEQGVSALQNNFFISSLMEAMQQAPDGAHDPEDPHPLS----AVAGRPLSCPNHEGKTMEFYCEACETAMCGECRAGEHREHGTVLLRDVVEQHKAALQRQLEAVRGRLPQLSAAIALVGGISQQLQERKAEALAQISAAFEDLEQALQQRKQALVSDLESICG------------------------------------------------------------------------------------AKQKVLQTQLDTLRQGQEHIGSSCSFAEQALRLGSAPEVLLVRKHMRER----------------------------------------------------------------------------------------------------------------------------LAALAAQAFPERPHENAQLELVLEVDGLRRSVLNLGALLTTSAAAHETVATGEGLRQALVG-----------------------------------------------------------------------------------------------QPASLTVTTKDKDG----RLVRTGSAELCAEITG----------------------------PDGMRLAVP-VVDHKNGTYELVYTARTEGDLLLSVLLYGQPVRGSPFRVRALRPGDLPPSPDDVKRRVKSPGG---PGSHVRQKAVRRPSSMYSTGGKRKDNP------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------IVDELVFRVGSRGREKGEFTNLHPLSAASSGRIVVADSNNQCIQVFSNEGQFKFRFGVRGRSPGQLQRPTGVAVDTNGDIIVADYDNRWVSIFSPEGKFKTKIG-----AGRLMGPKGVAVDRNGHIIVVDNKSCCVFTFQPNGKLVGRFGGRGATDRHFAG--------------------PHFVAVNNKNEIVVTDFHNHSVKVYSADGEFLFKFGSHGEGNGQFNAPTGVAVDSNGNIIVADWGNSRIQVFDSSGSFLSYIN---TSAEPLYGPQGLALTSDGHVVVADAGNHCFKAYRYLQ", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9R1R2-1", "uniprot_id": "TRIM3_MOUSE", "id": "Q9R1R2-1", "name": "Tripartite motif-containing protein 3", "aln": "----MAKRE-DSPGPEVQPMDKQFLVCSICLDRYRCPKVLPCLHTFCER-CLQNYIPPQSLTLSCPVCRQTSILPEQGVSALQNNFFISSLMEAMQQAPEGAHDPEDPHPLS----AVAGRPLSCPNHEGKTMEFYCEACETAMCGECRAGEHREHGTVLLRDVVEQHKAALQRQLEAVRGRLPQLSAAIALVGGISQQLQERKAEALAQISAAFEDLEQALQQRKQALVSDLESICG------------------------------------------------------------------------------------AKQKVLQTQLDTLRQGQEHIGSSCSFAEQALRLGSAPEVLLVRKHMRER----------------------------------------------------------------------------------------------------------------------------LAALAAQAFPERPHENAQLELVLEVDGLRRSVLNLGALLTTSATAHETVATGEGLRQALVG-----------------------------------------------------------------------------------------------QPASLTVTTKDKDG----RLVRTGSAELCAEITG----------------------------PDGVRLAVP-VVDHKNGTYELVYTARTEGDLLLSVLLYGQPVRGSPFRVRALRPGDLPPSPDDVKRRVKSPGG---PGSHVRQKAVRRPSSMYSTGGKRKDNP------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------IEDELVFRVGSRGREKGEFTNLQGVSAASSGRIVVADSNNQCIQVFSNEGQFKFRFGVRGRSPGQLQRPTGVAVDTNGDIIVADYDNRWVSIFSPEGKFKTKIG-----AGRLMGPKGVAVDRNGHIIVVDNKSCCVFTFQPNGKLVGRFGGRGATDRHFAG--------------------PHFVAVNNKNEIVVTDFHNHSVKVYSADGEFLFKFGSHGEGNGQFNAPTGVAVDSNGNIIVADWGNSRIQVFDSSGSFLSYIN---TSAEPLYGPQGLALTSDGHVVVADAGNHCFKAYRYLQ", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O75382-1", "uniprot_id": "TRIM3_HUMAN", "id": "O75382-1", "name": "Tripartite motif-containing protein 3", "aln": "----MAKRE-DSPGPEVQPMDKQFLVCSICLDRYQCPKVLPCLHTFCER-CLQNYIPAQSLTLSCPVCRQTSILPEQGVSALQNNFFISSLMEAMQQAPDGAHDPEDPHPLS----VVAGRPLSCPNHEGKTMEFYCEACETAMCGECRAGEHREHGTVLLRDVVEQHKAALQRQLEAVRGRLPQLSAAIALVGGISQQLQERKAEALAQISAAFEDLEQALQQRKQALVSDLETICG------------------------------------------------------------------------------------AKQKVLQSQLDTLRQGQEHIGSSCSFAEQALRLGSAPEVLLVRKHMRER----------------------------------------------------------------------------------------------------------------------------LAALAAQAFPERPHENAQLELVLEVDGLRRSVLNLGALLTTSATAHETVATGEGLRQALVG-----------------------------------------------------------------------------------------------QPASLTVTTKDKDG----RLVRTGSAELRAEITG----------------------------PDGTRLPVP-VVDHKNGTYELVYTARTEGELLLSVLLYGQPVRGSPFRVRALRPGDLPPSPDDVKRRVKSPGG---PGSHVRQKAVRRPSSMYSTGGKRKDNP------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------IEDELVFRVGSRGREKGEFTNLQGVSAASSGRIVVADSNNQCIQVFSNEGQFKFRFGVRGRSPGQLQRPTGVAVDTNGDIIVADYDNRWVSIFSPEGKFKTKIG-----AGRLMGPKGVAVDRNGHIIVVDNKSCCVFTFQPNGKLVGRFGGRGATDRHFAG--------------------PHFVAVNNKNEIVVTDFHNHSVKVYSADGEFLFKFGSHGEGNGQFNAPTGVAVDSNGNIIVADWGNSRIQVFDSSGSFLSYIN---TSAEPLYGPQGLALTSDGHVVVADAGNHCFKAYRYLQ", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M2B1X4-1", "uniprot_id": "A0A8M2B1X4_DANRE", "id": "A0A8M2B1X4-1", "name": "RING-type E3 ubiquitin transferase", "aln": "MSVTMAKFETGRTSPVVRQIDKQFLVCSICLDHYHNPKVLPCLHTFCER-CLQNYIPPQSLTLSCPVCRQTSILPEKGVAALQNNFFITNLMEVLQRDSE-CSRPEACSVLESVSAAAAGKPLSCPNHEGKVMEFYCESCETAMCLECTEGEHREHVTVPLRDVLEQHKAVLKNQLDAIRNRLPQLTAAIEMVNEISKQLTERKNEAVNEINMTFEELERALHQRKAALITDLENICS------------------------------------------------------------------------------------TKQKVLQAQLSSLLQGKEHIQSSCSFTEQALSHGSATEVLLVQKQMSER----------------------------------------------------------------------------------------------------------------------------VSALACHDFPERPHENAHLDCQIETEGLRRSIQNLGVLLTTGAVGHTSVATGEGLRHALVG-----------------------------------------------------------------------------------------------QHVTVTVTTKDKDS----ELVRTGNAALRAEIMG----------------------------QDGAQVTEAEVVDNKNGTYEVGYTLKGEGEYLFSLILYGQPVRGSPFKLRAIKPSDVPQSPDDVKRRVKSPSG---TGGHIRQKAVRRPSSMYSTT-KKKENP------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------IEDELIYRVGTRGREKGEFTNLQGISASISGRVIVADSNNQCIQVFTNDGQFKARFGVRGRSPGQLQRPTGVAVDTNGDVIVADYDNRWISIFSPDGKFKNKIG-----AGRLMGPKGVAVDRNGHIIAVDNKACCVFIFQSNGKLVTKFGARGTSDRQFAEKSGSKCALEQKFSKSGPGFSPHFVAVNNKNEIVVTDFHNHSVKVYSADGEFLFKFGSHGEGNGQFNAPTGVAVDVNGNIIVADWGNSRIQVFDSAGSFLSYIN---TSADPLYGPQGLALTSDGHVVVADSGNHCFKVYRYLQ", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "E7F1U3-1", "uniprot_id": "E7F1U3_DANRE", "id": "E7F1U3-1", "name": "RING-type E3 ubiquitin transferase", "aln": "MPLTMAKRESGSTSPVVRQIDKQFLVCSICLEHYHNPKVLPCLHTFCER-CLQNYIPPQSLTLSCPVCRQTSILPEKGVAALQNNFFITNLMEVLQREQD-CTRSEASSGLESAGAATYAPPLSCPNHEGKVMEFYCESCETAMCLECTEGEHREHVTVPLRDVLEQHKAALKNQLDAIRNRLPQLTAAIELVNEISKQLTDRKNEAVTEISNTFEELEKALHQRKTTLITDLENICS------------------------------------------------------------------------------------TKQKVLQGQLAALMQGKENIQSSCSFTEQALNHGSPTEVLLVQKQMGER----------------------------------------------------------------------------------------------------------------------------MGALARHAFPEQPHENGHLDCQVETEGLRRSIQNLGVLLTTSSVGHTSVATGEGLRHAVVG-----------------------------------------------------------------------------------------------QNTTVTVTTKDKDG----ELVKTGNAALRAQISG----------------------------ADGG-VTETDVTDNKNGTYEIGYTLRSEGEFSFSVLLYGRHVRGSPFRLRAVKACDAPQSPDDVKRRVKSPGGGGGAGGHVRQKAVRRPSSMYSTT-KKKENP------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------IEDELIFRVGTRGRERGEFSNLQGISTTSSGRIVVADSNNQCIQVFSNDGQFKLKFGVRGRSPGQLQRPTGVAVDMNGDIIVADYDNRWLSIFSPDGKFKNKIG-----AGRLMGPKGVAVDKNGHIITADNKACCVFIFQSNGKLVTKFGAKGTSERQFADKSAPNTPTEPKQSKSGPAFSPHFVAINNKNEIVVTDFHNHSVKVYNADGEFLFKFGSHGEGNGQFNAPTGVAVDGNGNIIVADWGNSRIQVFDSSGSFLSYIN---TTADPLYGPQGLALTSDGHVAVADSGNHCFKVYRYLQ", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "B7YZK8-1", "uniprot_id": "B7YZK8_DROME", "id": "B7YZK8-1", "name": "", "aln": "-----------------MEQFEQLLTCCVCLDRYRIPKLLPCQHSFCMEPCMEGLVDYVRRQVKCPECRAEHRIPYNGVQAFPTNVTLQRFLELHIEITGELPDPTSGQIMERCGVCSEKAYLSHCAHCEKKICEDCKSAHMDILRREIT-RFNSQIRRSLHRLQDSLAIIEKNTMSLQTNAISVTEEIDEIYQRITKAIKDRSDQLKGEIDRYLAVELRNLTTLKENLDLEITNITSNCDTVDKYMNETVEWDDCELMDTKEIFLKTVEFLRHFEYENNDYSRRVRFLVSIDPNQLVMNLATFGDLNIAPHSTPSGGSVSSSHLAPPSALQPGLMRSKSDHRLATQFRQQEERSGYNDEPVLGGRKFGERPQRSATQANNDRYGRSGGDYDYENDYDNEGSSGRAGKSSRFRSRFVRSHQNDDSDSEQQQQQRQQELKERKDRVLDSEDVSRGQLSGIIRLSDCSRVVQRLADIGKEKKEKKSDAAAAAQAAVQAAIQAQKAAMQRQQQKNQQNAADEEELARQKRKNAGSSSTGGAATSTSSGGGDTASDQRVAALKNRGGEESDGSSNQAASPVRNSAASTTRAEVSVNEANTEEEGVASESSDSEEDEEVEDEDEEEEVDEEEEQVEESVEEEEAPRELLNLPEEALQPTSSEVTEEEESSSEYEEVTATESEEEQEEVEGRVIEIESQDLPVINVLPPENDIAHKVEESPVDHISNQELMEETDKSTDESPEEEEEEEYTEEEIESKPPVSAQVAAVKKTQRSGSSDSSASTESSASSAAAAAVAATSTSATAAAPATSSSNSTSQNAKAPSSSRYSTARDTTAVPEKKPFVSRFLPQHSTASTTNGSADKKKAESSSSSEEETSSESESESEPETKAKSSATSSTTNTKSTPNSAASSTTAASSSTTSGSYRDRLEARRASRDDSSSTAAGRSSYATPSSSGYGSGSGTTGGRTRAVPAPHHTSESEDRYGSGTGSSYTSRFLNKSKSSAIVTQPSLSTPTASFDEDATGTGDDSDSRYGTGRSRYLAMKERRTRLARSRSSHQFGNDDEDLDEPVSPTTVSPSAYLASRCAYSGYGSSDLSRSRSSHALKSRDNSPITDRGAGSSRSSGLGGSSTTDSKDGEALSSWARYLKNKYGNKSSKDSAGSSGSARDTHAGSSTSSSAAASSSHAHGYGSGTSGSSGRSTASDVSRRLSLGLPLRQANELASSDDDGSKNGLGSPTSPTVAAAVAAAGITGAAGTIPKQVYLRKRQQLFQLGGRGSEPGSFTWPRGLAVGPDNSIVVADSSNHRVQVFDSNGIFVKEFGEYGNGEGEFDCLAGVAVNRIGQYIIADRYNHRIQVLDPQGRFLRAFGSQGTADGKFNYPWGVTTDALGFIYVCDKENHRVQVFQSDGSFVGKFGSCGRGEGQLEH--------------------PHYIAVSNTNRVIVSDSNNHRIQIFDVNGKVLSTVGGEGSDDGQFKFPRGVAVDDQGYIFVADSGNNRIQIFNPDGSFLKTFGSWGSGDSEFKGLEGVAIMSNGNILVCDRENHRVQVF----", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :*:*.*.:**::*: **:*** *:** . *::. : :.** ** :* :** *: .*. : ::* . . :. ** * * : *::.. : . ....: *: : :. :. :. . :. : *:: : :*. : :*. : : * * * :: .* . :: . * :.:.. : .* :* * * :* ::: ** . * : :: ::: : : * : *:. * * * .:. : . *: . *. * .: ** :::.. .:. * . :: * :. : :..: : : . * : . : * .. :: : . . *. ..: ..*... .. .*. .:* .: :. . * : ::::* ** * *.*: : ::. .. ::****.*: :*** .:* * .** *.. *::: :****: *: *:** *: :.::.*:*:* :* *:: * **:.* *.* . *:: * **.:*.:* :**. * : :: **::*:.*.*.::*:* :** ::::..:*:.* ..*..*..:***: * ***** :* *:*** **.***:*:. ****. :. : . : * :*:*: *:*:: *.* ** .:.: ", "identical_positions": 161, "similar_positions": 261, "identity": "10.33%" }, { "cls_id": "homologset.agr.MGI:1860055", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P60570-1", "uniprot_id": "PANX1_RAT", "id": "P60570-1", "name": "Pannexin-1", "aln": "MAIAHLATEYVFSDFLLKEPTEPKFKGLRLELAVDKMVTCIAVGLPLLLISLAFAQEISIGTQISCFSPSSFSWRQAAFVDSYCWAAVQQKNSLQSESGNLPLWLHKFFPYILLLFAILLYLPALFWRFAAAPHLCSDLKFIMEELDKVYNRAIKAAKSARDLDLRDGPG-PPGVTENVGQSLWEISESHFKYPIVEQYLKTKKNSSHLIMKYISCRLVTFAVVLLACIYLSYYFSLSSLSDEFLCSIKSGVLRNDSTIPDSFQCKLIAVGIFQLLSLINLLVYALLVPVVIYTLFVPFRQKT--DVLKVYEILPTF-DVLHFK--SEGYNDLSLYNLFLEENISELKSYKCLKVLENIKSNG-QGIDPMLLLTNLGMIKMDVIDGKVPMSLQTKGEDQGSQRMDFKDLDLS--SETAANNGEKNSRQRLLNSSC", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9JIP4-1", "uniprot_id": "PANX1_MOUSE", "id": "Q9JIP4-1", "name": "Pannexin-1", "aln": "MAIAHLATEYVFSDFLLKEPTEPKFKGLRLELAVDKMVTCIAVGLPLLLISLAFAQEISIGTQISCFSPSSFSWRQAAFVDSYCWAAVQQKSSLQSESGNLPLWLHKFFPYILLLFAILLYLPALFWRFSAAPHLCSDLKFIMEELDKVYNRAIKAAKSARDLDLRDGPG-PPGVTENVGQSLWEISESHFKYPIVEQYLKTKKNSSHLIMKYISCRLVTFVVILLACIYLSYYFSLSSLSDEFLCSIKSGVLKNDSTIPDRFQCKLIAVGIFQLLSLINLIVYALLIPVVVYTFFIPFRQKT--DILKVYEILPTF-DVLHFK--SEGYNDLSLYNLFLEENISELKSYKCLKVLENIKSNG-QGIDPMLLLTNLGMIKMDIIDGKIPTSLQTKGEDQGSQRVEFKDLDLS--SEAAANNGEKNSRQRLLNPSC", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q96RD7-1", "uniprot_id": "PANX1_HUMAN", "id": "Q96RD7-1", "name": "Pannexin-1", "aln": "MAIAQLATEYVFSDFLLKEPTEPKFKGLRLELAVDKMVTCIAVGLPLLLISLAFAQEISIGTQISCFSPSSFSWRQAAFVDSYCWAAVQQKNSLQSESGNLPLWLHKFFPYILLLFAILLYLPPLFWRFAAAPHICSDLKFIMEELDKVYNRAIKAAKSARDLDMRDGACSVPGVTENLGQSLWEVSESHFKYPIVEQYLKTKKNSNNLIIKYISCRLLTLIIILLACIYLGYYFSLSSLSDEFVCSIKSGILRNDSTVPDQFQCKLIAVGIFQLLSVINLVVYVLLAPVVVYTLFVPFRQKT--DVLKVYEILPTF-DVLHFK--SEGYNDLSLYNLFLEENISEVKSYKCLKVLENIKSSG-QGIDPMLLLTNLGMIKMDVVDGKTPMSAEMR-EEQGNQTAELQGMNID--SETKANNGEKNARQRLLDSSC", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F1QSR7-1", "uniprot_id": "F1QSR7_DANRE", "id": "F1QSR7-1", "name": "Pannexin", "aln": "MAIARVATEYVFSDFLLKEQSDSKYKGVRLELATDKLVSFIAVGLPLLLISLAFAQEVSVGTQITCFPPTNFTMRQAAYADSFCWAAVEHHPS-ENETYSAPLHLHKFFPYILLLLAILMYIPALFWRFTAAPSLSSDLSFIMEELDRCYNRAIRLAKSITTKQDK-------DIAEDP-HSGLELTEACFKYPLVEQYLKTKRSSWALAAKYLLCRVLTFLTLLLGCFYLTYYIFWVSPSDQFSCHLRRGILVNQSEVPDVVQCKLVAVGVFRLLSCMNLVVYLLLVPAVVYAGLQPARQHQRGQFLRPYHLLPAFGHVLDLQPATRRYDDLSIYLLFLEENLSELKSYKCLQVLELLSEGGEAAFDTMCLLRTLGQVKTDMVDKRQAQTVNGNPEIVISEIKDVSVLLDDGVQADKSCSCVKDVRQRVV----", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "****::************* ::.*:**:*****.**:*: *****************:*:****:**.*:.*: ****:.**:*****::: * :.*: . ** ***********:***:*:*.*****:*** :.***.*******: *****: *** : : .::*: :* *::*: ****:********:.* * **: **::*: :**.*:** **: * **:* * :: *:* *:* :** .****:***:*:*** :**:** ** *.*:*: : * **: :.*: *.:**:* .**.:: :. *:***:* ******:**:******:*** :...* .:*.* ** .** :* *::* : . : : . * .: :.. : . . : . *: ***:: ", "identical_positions": 219, "similar_positions": 121, "identity": "50.34%" }, { "cls_id": "homologset.agr.MGI:1860075", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O70489-1", "uniprot_id": "PPT2_RAT", "id": "O70489-1", "name": "Lysosomal thioesterase PPT2", "aln": "-------------------------------MPGLWRQRLPSAWALLLLPFLPLLLPAAPAPHRGSYKPVIVVHGLFDSSYSFRHLLDYINETHPGTVVTVLDLFDGRESLRPLWEQVQGFREAVVPIMEKAPEGVHLICYSQGGLVCRALLSVMDEHNVDSFISLSSPQMGQYGDTDYLKWLFPTSMRSNLYRICYSPWGQEFSICNYWHDPHH-----------DDLYLNASSFLALINGERDHPNATAWRKNFLR------------------------------------VGRLVLIGGPD------------DGVITPWQSS--------------------------------------FFG-----------------FYDANETVLEMEEQPVYLRDSFGLKTLLARGAIVRCPMAGVSHTTWHSNRTLYDA--------------------------------------------CIEPWLS---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O35448-1", "uniprot_id": "PPT2_MOUSE", "id": "O35448-1", "name": "Lysosomal thioesterase PPT2", "aln": "-------------------------------MPGLWRQRLPSAWALLLLPFLPLLMPAAPAAHRGSYKPVIVVHGLFDSSYSFRHLLDYINETHTGTVVTVLDLFDGRESLRPLWEQVQGFREAVVPIMEKAPEGVHLICYSQGGLVCRALLSVMDNHNVDSFISLSSPQMGQYGDTDYLKWLFPTSMRSNLYRVCYSPWGQEFSICNYWHDPHH-----------DDLYLNASSFLALINGERDHPNATAWRKNFLR------------------------------------VGRLVLIGGPD------------DGVITPWQSS--------------------------------------FFG-----------------FYDANETVLEMEEQPVYLRDSFGLKTLLARGAIVRCPMAGISHTTWHSNRTLYDT--------------------------------------------CIEPWLS---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9UMR5-1", "uniprot_id": "PPT2_HUMAN", "id": "Q9UMR5-1", "name": "Lysosomal thioesterase PPT2", "aln": "-------------------------------MLGLCGQRLPAAWVLLLLPFLPLLLLAAPAPHRASYKPVIVVHGLFDSSYSFRHLLEYINETHPGTVVTVLDLFDGRESLRPLWEQVQGFREAVVPIMAKAPQGVHLICYSQGGLVCRALLSVMDDHNVDSFISLSSPQMGQYGDTDYLKWLFPTSMRSNLYRICYSPWGQEFSICNYWHDPHH-----------DDLYLNASSFLALINGERDHPNATVWRKNFLR------------------------------------VGHLVLIGGPD------------DGVITPWQSS--------------------------------------FFG-----------------FYDANETVLEMEEQLVYLRDSFGLKTLLARGAIVRCPMAGISHTAWHSNRTLYET--------------------------------------------CIEPWLS---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AC58HX37-1", "uniprot_id": "A0AC58HX37_DANRE", "id": "A0AC58HX37-1", "name": "palmitoyl-CoA hydrolase", "aln": "-------------------------------MKGACVWTLVSVCVFCVC---------------VAYKPVIVVHGLFDSSADFVHLHRFINLSHPGTNVTVLDLFDRSASLQPLWKQVEGFTEAIYPIMQNAADGVHLICYSQGGLVCRGILSTLPDHNVHSFISLSAPQAGQYGDTDYLKYLFPQFVKSNLFHVCYTAVGQKISICNYWNDPHH-----------RDMYINSSDYLALLNNERPNPNSTAWKQNFLR------------------------------------IKKLVLIGGPD------------DGVITPWQSS--------------------------------------QFG-----------------FYDDNETVVEMKNQKVFLMDLFGLKTLSARGDLALCSVEGVAHIFWHSNETYFSALHQNRH-------------------------------------FCYSDSASMENP-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "F1RD68-1", "uniprot_id": "F1RD68_DANRE", "id": "F1RD68-1", "name": "palmitoyl-CoA hydrolase", "aln": "-------------------------------MTDSSRPCVFIWAVLLLLP-----------TVIMAYRPVILVHGLFGGPEQMEMLKKYIKRSHPGTSVTAISLYDDNASSKPMWEQVDGFREAIRPIMDRAKDGVHLICYSQGGLICRGVLATLPHHNVHSVIFLSSPLAGQYGDSNYISKFFPSFVKSTLYNACYTTRGQQISSCSYWKDPHQ-----------IEKYLKYSVFLAPLNGEVETVHTQAWRKNFLR------------------------------------IKTMVLLGGPD------------DGTIKPWQSS--------------------------------------MFG-----------------FYNRNEKVIDMEHQDYYISDSFGLKTLNRRKAIVKCIIPDVHHDAWPTDYKIYKK--------------------------------------------CIEKWLT---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "E7FC96-1", "uniprot_id": "E7FC96_DANRE", "id": "E7FC96-1", "name": "palmitoyl-CoA hydrolase", "aln": "-------------------------------MADGCRPCVFILVVLLLLP-----------SAIMAYRPVIIIHGLFGGPKELTPFVNFIKESHPGTSVTAPSLYEYAASVKPMWVQVEGFKKVIQPIMESAEDGVHLICYSQGGLICRGVLATLPQHNAHSVIFLSSPLAGQYGVTRAISGVFPKLPKSSLHNVCYTELGQKTSFCSYWNDPHH-----------REKYLNSSVFLAPLNGEVEHVNSTEWRNNFLR------------------------------------IKTMVLIGGPN------------DGVILPWQSS--------------------------------------MFG-----------------SYDRNGKVIDMENQDFYVRDTFGLKTLKSQGVLWKCIIPRVKHNSWPSDPRVFQN--------------------------------------------CVEKWLT---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VKH6-1", "uniprot_id": "PPT2_DROME", "id": "Q9VKH6-1", "name": "Lysosomal thioesterase PPT2 homolog", "aln": "-----------------------------------MRLRLQVLVALLTCS---------SISVSLAYKPVVILHGILSGAESMASLVREIEEFHPGTIVYNCDKFNGWYSLENAWRQVDQVRDYLNEVGKLHPEGIIVLGYSQGGLLARAAIQSLPEHNVKTFISLSSPQAGQYG-TSFLHLIFPDLAAKTAFELFYSRVGQHTSVGGYWNDPQR-----------QDLYLKYSEFLPLINNEKKTSNSTSFKMGMVR------------------------------------LNKLVMIGGPN------------DDVITPWQSS--------------------------------------HFG-----------------YFDENMDVIPFIRRPIFTSDSIGIRTLQEAGKLIIVVKPHVHHLAWHTRRDVIHE--------------------------------------------VIFPYLD---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "E7F6F8-1", "uniprot_id": "E7F6F8_DANRE", "id": "E7F6F8-1", "name": "", "aln": "MMSTRGKIEGCRICGSDLQGNQRRWLYANQNRKGAQTQTPTDFSSKASLPRSAQSSPWGSTLSLSSSHSLSQSRGLLTPTKGIDLLCVLTHILDQPVPRADGHGEFLCGKCVSVLERVFKFDTVISRVRMLSSERLQKLTQERD-KIRRWVRSMYDQRNPSPFRSKGSSSEDENDRKDSAGEGYREMLKDNMALSEYEWWSEKAEACPYYRRTGKRCQKGKKCEGCDSLRVSDSDYESVCGIPRHLPEQAFATLGLSREKSCSMPLHWSRVPSVRSSPASLSGSCHSLRSRTASIQSLDSLDGADPFDWPEDNFAIIDAVFKKLRGMEGKPVQSPAGSRIPVLNRGDVVNGKDEVGSKTGLVRVLNFGEGENGTENEFEEENDDILTELKDDFVPLQRESSSNRVHVAVKQLREQLVQAQARIRTLEAQLRDANKTTTDASAKQLKSPQATILKNKNDLIESLSQSLHSRESVIQECVTLIQKLCAEKGLESKDTDRLIQKLAGAVTDTRSERETVLEAQLSEASEREKALEKQLQAIKDAGRERDRDFITLNTVLQCNQDVINHQRVELAERDRAQQEMMKEWEVWKERDSALTALVQDNKDYISQLKEALESSRRDVQALSDSLIGRGLEGGGAETGLVNQLREKDVLLVESFKDREELSTTMLQEISRLSSALTKAESLILEQRENHKQAITALSEQLKNTLKELREKAKERKEAELGWKKENKERAFEEGKLRDNLQKRDQLIEQVLLELEERDGVLTELQQNISSKLGPKTALKHTL", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : :.: :*:: . : : . . . . :* . : : : : : .:. : * .:* .. .:. .: . . : .. * .:. . *:. . : . :. * : . . . .: * : : :.*.: * .: :. ** : : .: : .. ..:: * : : ", "identical_positions": 13, "similar_positions": 79, "identity": "1.66%" }, { "cls_id": "homologset.agr.MGI:1860076", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q5M807-1", "uniprot_id": "RNF5_RAT", "id": "Q5M807-1", "name": "E3 ubiquitin-protein ligase RNF5", "aln": "MAAAEEE----------------DGGPEGP----NRERGGASATFECNICLETAREAVVSVCGHLYCWPCLHQWLETRPDRQECPVCKAGISREKVVPLYGRGSQKPQDPRLKTPPRPQGQRPAPESRGGFQPFGDAGGFHFSFGVGAFPFGFFTTVFNAHEPFRRG---AGVDLGQGHPASS---WQDSLFLFLAIFFFFWLLSI", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O35445-1", "uniprot_id": "RNF5_MOUSE", "id": "O35445-1", "name": "E3 ubiquitin-protein ligase RNF5", "aln": "MAAAEEE----------------DGGPEGP----NRERGGASATFECNICLETAREAVVSVCGHLYCWPCLHQWLETRPDRQECPVCKAGISREKVVPLYGRGSQKPQDPRLKTPPRPQGQRPAPESRGGFQPFGDAGGFHFSFGVGAFPFGFFTTVFNAHEPFRRG---AGVDLGQGHPASS---WQDSLFLFLAIFFFFWLLSI", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q99942-1", "uniprot_id": "RNF5_HUMAN", "id": "Q99942-1", "name": "E3 ubiquitin-protein ligase RNF5", "aln": "MAAAEEE----------------DGGPEGP----NRERGGAGATFECNICLETAREAVVSVCGHLYCWPCLHQWLETRPERQECPVCKAGISREKVVPLYGRGSQKPQDPRLKTPPRPQGQRPAPESRGGFQPFGDTGGFHFSFGVGAFPFGFFTTVFNAHEPFRRG---TGVDLGQGHPASS---WQDSLFLFLAIFFFFWLLSI", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1RFK9-1", "uniprot_id": "A0A8M1RFK9_DANRE", "id": "A0A8M1RFK9-1", "name": "E3 ubiquitin-protein ligase RNF185", "aln": "MEAAEQQRSSSDGAAARGAGFPGSGGGAGPGGGAEGERDRERATFECNICLDTARDAVISLCGHLFCWPCLHQWLETRPSRQQCPVCKAGISRDKVIPLYGRGSSSQEDPRLKTPPRPQGQRSEPESRGPFQGFGDTG-FHMSFGIGAFPFGFFTTVFNTNNPFHRADAHYGADQQANENANNGNNWQDSLFLFLAIFFFFWILSV", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q8IQM1-1", "uniprot_id": "Q8IQM1_DROME", "id": "Q8IQM1-1", "name": "RING-type E3 ubiquitin transferase", "aln": "MSADTFV-----------------------------MDTKDESFYECNICLDTAQNAVVSMCGHLFCWPCLYQWILTKPDHTVCPVCKSGVDRSKVIPVYARNDKRQEDPRDKTPPRPTGIWSDYANDLELGLF-----SYLLFGL-FFPYGALSSYLDMDEPLNPAAD-HGIRDGQNETLLS------KFFLYVAIMLIIYMIVI", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* * : :******:**::**:*:****:*****:**: *:*.: *****:*:.*.**:*:*.*... :*** ****** * . . : * :: **: **:* ::: :: .:*:. . * .. . .:**::**::::::: :", "identical_positions": 60, "similar_positions": 56, "identity": "29.13%" }, { "cls_id": "homologset.agr.MGI:1860077", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "F1M9U4-1", "uniprot_id": "F1M9U4_RAT", "id": "F1M9U4-1", "name": "MutS protein homolog 4", "aln": "MCSLRLRLRDGSTAHAPSLPPFQWHGFRPWGTRGLTRRASSVRKAREMLRQEATSLSSSPRWTPSRREVPRRRTPASASRPSTEGAVADRSSSSSSSS-PAPAA--APGSSFGNKRSYTTHKAASNFPVGTSSSSAQDTTYPHTFRTPLSAGNPQRS-YKGWTPQVGLSATSS-AVSAHAPSVIVAVVEGRGLARGEIGMASIDLKSPQIMLSQFADNTTYAKVITKLQVLSPLEIIMSNTACVVGNSTKLFTLITENFKNVNFTTVQRKYFNETKGLEYIEQLCIAEFSS--VLMEVQSRYYCLAAAAALLKYVEFIQN----SVYAPKSLKIYFQGSEQTAMIDSSSAQNLELLVNNQDYRSNHTLFGVLNYTKTAGGSRRLRSNILEPLVDVETISMRLDCVQELLQDEELFYGLQSVISRFLDTEQLLSVLVQIPKQDTVNAAESKITNLIYLKHTLELVDPLKVALKN--CSTPLLRAYYGSLEDHRFGLILEKIKTVINDDARYMKGCLNMRTQKCYAVRSNISEFLDIARRTYTEIVDDIAGMISQLAEKYSLPLRTSFSSARGFFIQMTTDCAALSSDQLPSEFIKISKVKNSYSFTSADLIKMNERCQESLREIYHMTYMIVCKLLSEIYEHIHCLYKLSDTVSMLDMLLSFAHACTLSDYVRPEFTDTLAIKQGWHPILEKISAEKPVANNTYITEGSNVLIITGPNMSGKSTFLKQIALCQIMAQIGSFVPAQYASFRIAAQIFTRISTDDDIETNSSTFMKEMKEIAYILHNANDKSLILIDELGRGTNTEEGTGISYAVCEHLLSTKAFTLFTTHFLELCHIDTLYLNVENMHFEVQHVKNTSRNKDAILYTYKLSRGLTEEKHYGLKAAEASSLPPSIVLDAREITTQITRQISQNRRSSPEMDRQRAVYHLATRLVQVARNSQLEPDRLRTYLSNLKKKYEGDFPRAADLPEKTEE---", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q99MT2-1", "uniprot_id": "MSH4_MOUSE", "id": "Q99MT2-1", "name": "MutS protein homolog 4", "aln": "MCCLFLRLRDYSTAHALSLPPCQRCGLQPWSARSHARRTLGVRKAGEMLRQEAASLSSSPRWTPSRRDAPCGRTLASASRPSTEGAMADRSSSSSSS--PAPAS--APGSSFGNKRSYAIHRAASSFPVGTSSSSARDTTYPHTFRTPLSAGNPQRSGHKSWTPQVGYSATSS-AVSAHAPSVIVAVVEGRGLARGEIGMASIDLKSPQIMLSQFADNTTYAKVITKLQVLSPLEIIMSNTACVVGNSTKLFTLITENFKNVNFTTVQRKYFNETKGLEYIEQLCIAEFSS--VLMEVQSRYYCLAAAAALLKYVEFIQN----SVYAPKSLKIYFQGSEQTAMIDSSSAQNLELLVNNQDYRSNHTLFGVLNYTKTAGGSRRLRSNILEPLVDVETISMRLDCVQELLQDEELFFGLQSVISRFLDTEQLLSVLVQIPKQDTVNAAESKITNLIYLKHTLELVEPLKVTLKN--CSTPLLRAYYGSLEDHRFGLILDKIKTVINDDARYMKGCLNMRTQKCYAVRSNISEFLDIARRTYTEIVDDIAGMIAQLAEKYSLPLRTSFSSSRGFFIQMTTDCAALSSDQLPSEFIKISKVKNSYSFTSADLIKMNERCQESLREIYHMTYMIVCKLLSEIYEHIHCLYKLSDTVSMLDMLLSFAHACTLSDYVRPEFTDTLAIKQGWHPILEKISAEKPVANNTYITEGSNVLIITGPNMSGKSTYLKQIALCQIMAQIGSYVPAEYASFRIAAQIFTRISTDDDIETNSSTFMKEMKEIAYILHNANDKSLILIDELGRGTNTEEGIGISYAVCEHLLSIKAFTLFTTHFLELCHLDALYLNVENMHFEVQHVKNTSRNKDAILYTYKLSRGLTEEKNYGLKAAEASSLPSSIVLDARDITTQITRQILQNQRSSPEMDRQRAVYHLATRLVQAARNSQLEPDRLRTYLSNLKKKYAGDFPRAVGLPEKTEE---", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O15457-1", "uniprot_id": "MSH4_HUMAN", "id": "O15457-1", "name": "MutS protein homolog 4", "aln": "------MLRPEISSTSPSAPAVS-------PSSGETRSPQGPRYN--------FGLQETPQSRPS------VQVVSASTCPGTSGAAGDRSSSSSSLPCPAPNSRPAQGSYFGNKRAYAENTVASNFTFGASSSSARDTNYPQTLKTPLSTGNPQRSGYKSWTPQVGYSASSSSAISAHSPSVIVAVVEGRGLARGEIGMASIDLKNPQIILSQFADNTTYAKVITKLKILSPLEIIMSNTACAVGNSTKLFTLITENFKNVNFTTIQRKYFNETKGLEYIEQLCIAEFST--VLMEVQSKYYCLAAVAALLKYVEFIQN----SVYAPKSLKICFQGSEQTAMIDSSSAQNLELLINNQDYRNNHTLFGVLNYTKTPGGSRRLRSNILEPLVDIETINMRLDCVQELLQDEELFFGLQSVISRFLDTEQLLSVLVQIPKQDTVNAAESKITNLIYLKHTLELVDPLKIAMKN--CNTPLLRAYYGSLEDKRFGIILEKIKTVINDDARYMKGCLNMRTQKCYAVRSNINEFLDIARRTYTEIVDDIAGMISQLGEKYSLPLRTSFSSARGFFIQMTTDCIALPSDQLPSEFIKISKVKNSYSFTSADLIKMNERCQESLREIYHMTYMIVCKLLSEIYEHIHCLYKLSDTVSMLDMLLSFAHACTLSDYVRPEFTDTLAIKQGWHPILEKISAEKPIANNTYVTEGSNFLIITGPNMSGKSTYLKQIALCQIMAQIGSYVPAEYSSFRIAKQIFTRISTDDDIETNSSTFMKEMKEIAYILHNANDKSLILIDELGRGTNTEEGIGICYAVCEYLLSLKAFTLFATHFLELCHIDALYPNVENMHFEVQHVKNTSRNKEAILYTYKLSKGLTEEKNYGLKAAEVSSLPPSIVLDAKEITTQITRQILQNQRSTPEMERQRAVYHLATRLVQTARNSQLDPDSLRIYLSNLKKKYKEDFPRTEQVPEKTEE---", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AB32T720-1", "uniprot_id": "A0AB32T720_DANRE", "id": "A0AB32T720-1", "name": "", "aln": "---MFCSSTEEVTAGSSSEPERS----------SSTLTPYNLMNY--------SQIFGRQQDPPS-------SSVLLTSRESDD-VRISVCPGSSSDTLPSALSETTPTAAQGHLN--ISETAYRTNSSGGSSAHSWTSSTPQLKTTPALS-HHSRTPRRDLNMTTSSSASAS--HAARAP-VIVAVVEGRGLARGEIGMASINMKYPELVLSQFVDTGTYTKVITKLHNLTPMEILMPDTASVKGQGTKLYSLITETFPSVTFTAVLRRYFNEKKGLEFIQQLCVPEFTT--VLMEVQTKYYCLASASALLKYFEFVQK----SIYAPKSLKVTFSGSEQTAMIDAVSASNLELVVNHRNHRSEHTLFGVLNHTKTSGGERRLRSNILEPLLEVDTIKSRQDTIQELLQNEELFFSLKNAIAHFLDIDELLSALVQIPKQETIAVAEAKITQVIQLKHIVELVPSLKVMLQH--STTHLLTAYCKSLEDCRFNSILDHIKSLINDDTSYMKGSLTMRTQKCYAVRPNVSEFLDIARRAYTEVVDDIAGLVAQLGEKHNLPLRTSFSNARGFFIQMKLEGGALPGGKLPDEFIKVSKQKNNFSFTTLDLMKMNDHCEEALKDIFHMSYVVVSKLLNEVHEQIHCLYKLSDVVSMLDMLLSLANACTISNYVRPEFTDTLAIQQGRHPVLERISGQQPISNNSYISEGSNFVIITGPNMSGKSTFLKQVALVQIMAQIGCFVPAEYASVRIADQIFTRIGVDDDFETNSSTFMVEMKEVSYIIHNATNSSLIIIDELGRGTSPEEGIGICHSVCEFLINLKAFTLFATHFLELCQLQTLYPNVENQHMQVQHIRTGDGRAERVVYTYQLSRGHSEERNYGIRAAEMTNLPLDIIQEAKTVADKINQKLWAKHHSDPATLKQRADYRLATRLVQTARNSQLDRASLRHYLKGLKTQYLAEIQMIKENATELVEIEE", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P40965-1", "uniprot_id": "MSH4_YEAST", "id": "P40965-1", "name": "MutS protein homolog 4", "aln": "----------------------------------------------------------------------MSESNLSSFISTNYFNLRSAANSSNSISKPSTKKSIRNQKSPTNISSWALKKKTLQIAETTWENNEKDSTHSHYLMTGSMASRTATSLSRYSTNASLLGPSID--------CVLCCIYEVPRDISTRIGLCIINCNTGQMYLSDFMDSQIYIRVVHKLQIYQPTEILIPSSSLAPTVSKLATMIKFNVAETVKIEEGSRKCFNSQDGLAAITKYLMDDTKKDLKIEEIIDKTFALCAASAAISYMEEIISKSSRNLNAFRKLRIQFEGTENTMLIDSKTVRGLELVENKLDK-NGISLWKFLDTTSTKMGQRSLRNSILQPLTDRGSIEMRLEALEELKANDDLLQKLRLEMKSLPDLDKLFSRLLCIN--HSAIKPDQRINYVLLLKETLQSVKSLKDALNDQLIQSRLISETKKIFNNDAIMEIEKLINSCINEDCVWASSAIQLLNQRSYAVKSDSNGLLDVSRQIYKEVKEEFFREVEDLTAKNKINLDHNYDSARGFYLRIKRQEFTDDVATLPDVFISRTIKKNYIECTTLNIIKKNARLKEVMEEILLLSEETVDELLDKIATHISELFMIAEAVAILDLVCSFTYNLKENNYTIPIFTNNLLIRDSRHPLLEKVLKNFVPNTISSTKHSSSLQIITGCNMSGKSVYLKQVALICIMAQMGSGIPALYGSFPVFKRLHARVCN-DSMELTSSNFGFEMKEMAYFLDDINTETLLILDELGRGSSIADGFCVSLAVTEHLLRTEATVFLSTHFQDIPKIMSKKPAVSHLHMDAVLLNDNS-----VKMNYQLTQKSVAIENSGIRVVKKIFNPDIIAEAYNIHSLLKIAKARTENEDSNGVVDQKTINQMKRIHNLVAILKECAGNEKEPLTLGKLKEINSDFIENFEE---------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . . .*.* *:. : . . . :. .: * : . : : . ..: . *: .: * .**:. *: : :: **:* *. * :*: **: * **::..:: . .. : : .*.: *: **. .** * : : : .. : *: : :.*.:.:* :.*.* : . .: * :.*:: *.*:*:* :**: :. .***: *: : . :*: .*: *.* *.* **..**:** : :*. * : ::** :::*: *: : : * ::*:* *: * .: .: :*. :: **. :: * .** ::. : *: ::: : * . *:: **:* : ...: : .*:.***:.: . :**::*: *.*: ::: : :* * .: * .:..:***::::. : : **. **. : ** . *: :::* * : :* :.:* :: * :**.:: :* *: :::.*::**:: *:: . .:*. * **:.* *::. **:**:: : . : ...*.. **** ******.:***:** ****:*. :** *.*. : ::.:*: *.:* .**.* ****::*::.: . .:*:::******:. :* :. :* *.*: :* .:::*** :: :: : *.: *::. :. . : .*:*:: .: *::..: * * . : : :... *:: :: .* .: . . .: :: ", "identical_positions": 184, "similar_positions": 321, "identity": "18.89%" }, { "cls_id": "homologset.agr.MGI:1860078", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q920J4-1", "uniprot_id": "TXNL1_RAT", "id": "Q920J4-1", "name": "Thioredoxin-like protein 1", "aln": "MVGVKPVGSDPDFQPELSGAGSRLAVVKFTMRGCGPCLRIAPAFSSMSNKYPQAVFLEVDVHQCQGTAATNNISATPTFLFFRNKVRIDQYQGADAVGLEEKIKQHLENDPGSNEDTDIPKGYMDLMPFINKAGCECLNESDEHGFDNCLRKDLSFLESDCDEQLLITVAFNQPVKLYSMKFQGPDNGQGPKYVKIFINLPRSMDFEEAERSEPTQALELTEDDIKEDGIVPLRYVKFQNVNSVTLFVQSNQGEEETTRISYFTFIGTPVQATNMNDFKRVVGKKGESH", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8CDN6-1", "uniprot_id": "TXNL1_MOUSE", "id": "Q8CDN6-1", "name": "Thioredoxin-like protein 1", "aln": "MVGVKPVGSDPDFQPELSGAGSRLAVVKFTMRGCGPCLRIAPAFSSMSNKYPQAVFLEVDVHQCQGTAATNNISATPTFLFFRNKVRIDQYQGADAVGLEEKIKQHLENDPGSNEDADIPKGYMDLMPFINKAGCECLNESDEHGFDNCLRKDMSFLESDCDEQLLITVAFNQPVKLYSMKFQGPDNGQGPKYVKIFINLPRSMDFEEAERSEPTQALELTEDDIKEDGIVPLRYVKFQNVNSVTLFVQSNQGEEETTRISYFTFIGTPVQATNMNDFKRVVGKKGESH", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O43396-1", "uniprot_id": "TXNL1_HUMAN", "id": "O43396-1", "name": "Thioredoxin-like protein 1", "aln": "MVGVKPVGSDPDFQPELSGAGSRLAVVKFTMRGCGPCLRIAPAFSSMSNKYPQAVFLEVDVHQCQGTAATNNISATPTFLFFRNKVRIDQYQGADAVGLEEKIKQHLENDPGSNEDTDIPKGYMDLMPFINKAGCECLNESDEHGFDNCLRKDTTFLESDCDEQLLITVAFNQPVKLYSMKFQGPDNGQGPKYVKIFINLPRSMDFEEAERSEPTQALELTEDDIKEDGIVPLRYVKFQNVNSVTIFVQSNQGEEETTRISYFTFIGTPVQATNMNDFKRVVGKKGESH", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F6NTA0-1", "uniprot_id": "F6NTA0_DANRE", "id": "F6NTA0-1", "name": "", "aln": "MVGVKVIGNDSDFQAELSGAGSRLTVVKFTMSGCRPCVRIAPAFNMLSNKYPQVVFLEVDVHVCQATAAANNISATPTFLFFRNKVRVDQYQGADASGLEEKIKQHVENDPGSNEDSDIPKGYMDLMPFVNKAGCECLNESDDCGFDSCLIKDSTYLESDCDEQLLITMAFNQPVKLFSMKLLSADFAQAPKSVKIFINLPRSMGFDDAERSEATQTLDLSEEDYKDDGLIPLRYVKFQNVNSVTLFIKSNQGDEETTKINYLTFIGTPVQATNMNDFKRVVGKKGESH", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VRP3-1", "uniprot_id": "Q9VRP3_DROME", "id": "Q9VRP3-1", "name": "", "aln": "-MSVRVINDESHFQAELAQAGIQLVVVDFTASWCGPCKRIAPIFETFPTKYPKAIFLKVDVDKCQDTAAGQGVSAMPTFIFYRNRTKIDRVQGADVNGLEAKIQEHIGTSGGEEGGEDYGQGLMELNTFISKQECECLNEADDHNLKHALASAGGYLQSDCDEQLILSITFNQAVKIHSLKFKAPSH-LGPKDVKLFINQPRTIDFDMAESMNSVQDLSLAQKELESGVPVNLRYVKFQNVQNIQIFVKNNQSGGDVTQIDYIGFIGSPIMTTKMNDFKRVAGKKGESH", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :.*: :..:..**.**: ** :*.**.** * ** **** *. :..***:.:**:***. ** *** :.:** ***:*:**:.::*: ****. *** **::*: .. *.: . * :* *:* .*:.* ******:*: .:. .* . :*:*******:::::***.**:.*:*: ... .** **:*** **::.*: ** :..* *.*::.: :.. : *********:.: :*::.**. :.*:*.*: ***:*: :*:*******.*******", "identical_positions": 131, "similar_positions": 105, "identity": "45.33%" }, { "cls_id": "homologset.agr.MGI:1860080", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZIE7-1", "uniprot_id": "D3ZIE7_RAT", "id": "D3ZIE7-1", "name": "Olfactory receptor", "aln": "MEPSNRTAFSEFILKGFSGYPALEHLLFPLCSVMYLVTLLGNTAIVVVSILDARLHTPMYFFLGNLSILDICYTSTFVPLMLVHLLSSRKTISFSGCAIQMCLSLSTGSTECLLLAVMAYDRYLAICQPLRYPVLMSHRLCLMLAGTSWVLCLFKSVTETVIAMRLPFCGRHVIRHFTCEILAVLKLACGDTSVSDAFLLVGAILLLPVPLTLICLSYMLILATILRVPSATGRRKAFSTCSAHLAVVLLFYSTIIFMYMKPKSKEARISDQVFTVLYAVVTPMLNPIIYSLRNKEVKEAARKAWGSRWVCR", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9QZ18-1", "uniprot_id": "Q9QZ18_MOUSE", "id": "Q9QZ18-1", "name": "Olfactory receptor", "aln": "MEPSNRTAVSEFVLKGFSGYPALERLLFPLCSVMYLVTLLGNTAIVAVSMLDARLHTPMYFFLGNLSILDICYTSTFVPLMLVHLLSSRKTISFTGCAVQMCLSLSTGSTECLLLAVMAYDRYLAICQPLRYPVLMSHRLCLMLAGASWVLCLFKSVAETVIAMRLPFCGHHVIRHFTCEILAVLKLTCGDTSVSDAFLLVGAILLLPIPLTLICLSYMLILATILRVPSATGRSKAFSTCSAHLAVVLLFYSTIIFMYMKPKSKEARISDQVFTVLYAVVTPMLNPIIYSLRNKEVKEAARKAWGSRWACR", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8NGT2-1", "uniprot_id": "O13J1_HUMAN", "id": "Q8NGT2-1", "name": "Olfactory receptor 13J1", "aln": "MEPLNRTEVSEFFLKGFSGYPALEHLLFPLCSAMYLVTLLGNTAIMAVSVLDIHLHTPVYFFLGNLSTLDICYTPTFVPLMLVHLLSSRKTISFAVCAIQMCLSLSTGSTECLLLAITAYDRYLAICQPLRYHVLMSHRLCVLLMGAAWVLCLLKSVTEMVISMRLPFCGHHVVSHFTCKILAVLKLACGNTSVSEDFLLAGSILLLPVPLAFICLSYLLILATILRVPSAARCCKAFSTCLAHLAVVLLFYGTIIFMYLKPKSKEAHISDEVFTVLYAMVTTMLNPTIYSLRNKEVKEAARKVWGRSRASR", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*** *** .***.***********:*******.************:.**:** :****:******** ******.*******************: **:*****************: ************** ********::* *::*****:***:* **:*******:**: ****:*******:**:****: ***.*:*****:**::*****:************: ****** **********.******:*******:***:*******:**.**** ***************.** ..*", "identical_positions": 251, "similar_positions": 42, "identity": "80.45%" }, { "cls_id": "homologset.agr.MGI:1860083", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q5HZW5-1", "uniprot_id": "CD320_RAT", "id": "Q5HZW5-1", "name": "CD320 antigen", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MARCGAGRAAALGL-------VLRLLLGLRTGPEAAPAPTSA-------PAHTLVQVSGPRAGSCPTDTFKCLTSGYCVPLSWRCDGDRD-----------------------------CSD-------GSDEEECR-----------------IEPCAQ---------------------------------------NRQCQPQPALP------CSCDNISGCSAGSDKNL-NCSRSPCQEGELRCILDDVCIPHTWRCDGHPDCPDSSDEL-SCDT---------------------------------------------------------------------------------------------------------------------------------------DTETDKIFQEENATTSMSSMIVEKETSFRNVTVASAGHPSRNPNAYGVIAAAG-----------------------VLSAILVSATILILLR--LRGQGY---------------------LPPTGLLVAVKESLLLSERKTSLI-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9Z1P5-1", "uniprot_id": "CD320_MOUSE", "id": "Q9Z1P5-1", "name": "CD320 antigen", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MARGGAGRAVALGL-------VLRLLFGLRTGLEAAPAP-----------AHTRVQVSGSRADSCPTDTFQCLTSGYCVPLSWRCDGDQD-----------------------------CSD-------GSDEEDCR-----------------IESCAQ---------------------------------------NGQCQPQSALP------CSCDNISGCSDVSDKNL-NCSRPPCQESELHCILDDVCIPHTWRCDGHPDCLDSSDEL-SCDT---------------------------------------------------------------------------------------------------------------------------------------DTEIDKIFQEENATTTRISTTMENETSFRNVTFTSAGDSSRNPSAYGVIAAAG-----------------------VLSAILVSATLLILLR--LRGQGY---------------------LPPPGLLVAVKESLLLSERKTSLI-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9NPF0-1", "uniprot_id": "CD320_HUMAN", "id": "Q9NPF0-1", "name": "CD320 antigen", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSG--GWMAQVGAWRTGALGL-------ALLLLLGLGLGLEAAASPLS---------TPTSAQAAGPSSGSCPPTKFQCRTSGLCVPLTWRCDRDLD-----------------------------CSD-------GSDEEECR-----------------IEPCTQ---------------------------------------KGQCPPPPGLP------CPCTGVSDCSGGTDKKLRNCSRLACLAGELRCTLSDDCIPLTWRCDGHPDCPDSSDEL-GCGTN-------------------------------------------------------------------------------------------------------------------------EILPEGDATTMGPPVTLESVTSLRNATTMGPPVTLESVPSVGNATSSSAGDQSGSPTAYGVIAAAA-----------------------VLSASLVTATLLLLSW--LRAQER---------------------LRPLGLLVAMKESLLLSEQKTSLP-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VLZ6-1", "uniprot_id": "Q9VLZ6_DROME", "id": "Q9VLZ6-1", "name": "FZ domain-containing protein", "aln": "MAEQKQLEAIANETSSVTGLRRQPTKYPHGLNITVQTIDDDNEGSPKDHSDYTRASGDSCWSKTQKYHIGMLGSPETLAELQVRRYKYPLTANYYLNSKLERPEKPTPWMLLGYARSVCRWKYLRWPIIFVASVLLFFGLITYCLWLHDVSVARAKFLQRRYEATLTSTSSSSNEVWDEETTSSTERSPQETTRLEDMDDSDESTELPEIAFGDDGDPEAGGEDGDGDYDDTLLP--ADSIRFTSGHQNSFGVPIEQDKRMLQLLKELLHKPQATPAGNEPTLTRVSPTLPPPLSASGRPTEAMALTTPSTTNSGCQSTMLPMCQGVLDYDLTFNREGAAPRDAVSMAAYDSL-IRANCSVRAAEFICGALEPECRPLHIGQLPPCRRICKAILEACSIPIYNSDVLGELFDCNLYPDAHESHKCEDPTRRRDYCYGNEFQCHDGSCIPQN----WQCDKIKDCQGGEDEDE---QCLVCEPDEFRCRSNEKCLVEKYRCDQNIDCMDGSDEQ-DCDEYGSGDLAPFDESELNAFPRVFTYASFLSPNETNDKVYTYITATTDEDAGTETKFQIHQVAAPAPPVNSSAEEGAGGPKGFVNFRDSKEIMMTSDSETKFKYSQRANRTSVKFSVSAPTTPAARTSSAIPSSALVQQRERTTSTTTTSTTTSTTTSSITSTPSITSTTLIPINAATSEPNPYEVVTSLGGCPPQELRCVSGKCITVSQLCDKQIDCPDAADELMCVYR--ERPSRRRLTSTTAPPTTSSAPPETSTATTTTGPLSSTRRSLRTTPNRSRKPKS---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q8IQA9-1", "uniprot_id": "Q8IQA9_DROME", "id": "Q8IQA9-1", "name": "", "aln": "-------------------MLAEALGYGYLLAYVICLLCWPGEAYPASSSYRDLDICNHWDGRRHFLELGSPAGEVHARNVTTTAYRS-SPLVFKNDAVAGDVWYQCSLELVTCAECVIRVAFTYANFSKSCGNTGGKSSMCPCEHIQFSEPPYDSTISGQEFCGDGKVFRSKTRTLQLKFFYRASNAHVFSLQYFSERNVRIVSGSPKQSIVGNGSTKSQPQVISTPYFPMAYPRDYGIEHILTCEADNCQVR----LDFTDFQLGLTSTLEIFDSNGQMLDSYTGEHFRPPITVSSGKSLLLQFRGNSATGVGFRAEVSFVSSKQLKDERLVPYTDCGGMVTGPGGAITMMNMIENATDVRLFDCIWIIKPGNNYMMMKTHISLRVDDFYGMAARSELTIRQG------------------TTSDAVEIENVMWPNNGLSKESHVAPILNGYYIRLRGVFGMSSKLAIVYSVFNYLNCYIGSEFLCGNNHCISIRLHCDGFDHCGDGSDEPDSCEEDWAHLHHDRRWYSHKPNYYFPKIDQYPDLKTATGIFIISTLGIFGVLSGWMVILYRMGVRARHQRELQSHLQTISELLDRQDEDRTPDEPPSYEAPPDYEEVIKVGMQQELREPRRQRRARRAPPRDRSCSRAASNCTVQSVLPLHRSCTLERDQEQPSTSAAAMTHAVAATDTTEDAEHVQTMAQRMLLATAICGTAGTSLPAAKESGQRVQSVGISTSPSSLSAGGELPTAGGSATTPGSTADECTQGGDSLSISLTLGLPSTTAESPVTTDQNQLQKQSPEQTISNCTEHTFLKRSWLVVQQVPPGRGYRVRRLRHTFSSPEAFTSDELHLPYPDFLSYGTNLPHERSSSNFGSELSRDPSSYSVGKRARLTPEDTSGSETITQEMEQSNQTLQSHVIVESHPNHSESESEAEQQVSCFGAVAQRPKRRHRGHVRSRSFSNARGGSAGRRRLMQRSSSADLLMNYATMAVSTPQKTSEAMQRLFFI", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : . : : * : : . .:. : . * : .. . .: : . : . : : . * : . . . * .. .: *: :** .* *.*** .* . : * . .: . . : .. .:: . : . * : .* : .. ", "identical_positions": 16, "similar_positions": 60, "identity": "1.59%" }, { "cls_id": "homologset.agr.MGI:1860084", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9WU63-1", "uniprot_id": "HEBP2_MOUSE", "id": "Q9WU63-1", "name": "Heme-binding protein 2", "aln": "MAEEPEPDLGVAEGSEDQALEMPSWKAPEDIDPQPGSYEIRHYGPAKWVSTCVESLDWDSAIQTGFTKLNGYIQGKNEKEMKIKLTAPVTSYVEPGSSPFSESTITISLYIPSEQQPDPPRPSESDVFIEDRAEMTVFVRSFDGFSSGQKNQEQLLTLANILREEGKVFNEKVFYTAGYSSPFQLLDRNNEVWLIQKNEPSVENK", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D3ZHC4-1", "uniprot_id": "D3ZHC4_RAT", "id": "D3ZHC4-1", "name": "Heme-binding protein 2", "aln": "MAEE--PDLGVAEGSEEQAMEMPSWKAPENIDPQPGSYEIRHYGPAKWVSTCVESLDWDSAIQTGFTKLNGYIQGKNEKEMKIKLTAPVMSFVEPGSGPFSESTITISLYIPSEQQHDPPRPSESDVFIEDRGEMTVFVRSFDGFSSGQKNQEQLLTLANILREEGKVFNEKVFYTAGYSSPFRLLDRNNEVWLIQRNEPSDEDK", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9Y5Z4-1", "uniprot_id": "HEBP2_HUMAN", "id": "Q9Y5Z4-1", "name": "Heme-binding protein 2", "aln": "MAEPLQPDPGAAEDAAAQAVETPGWKAPEDAGPQPGSYEIRHYGPAKWVSTSVESMDWDSAIQTGFTKLNSYIQGKNEKEMKIKMTAPVTSYVEPGSGPFSESTITISLYIPSEQQFDPPRPLESDVFIEDRAEMTVFVRSFDGFSSAQKNQEQLLTLASILREDGKVFDEKVYYTAGYNSPVKLLNRNNEVWLIQKNEPTKENE", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*** ** *.**.: **:* *.*****: .*******************.***:**************.*************:**** *:*****.****************** ***** *********.**************.***********.****:****:***:*****.**.:**:*********:***: *::", "identical_positions": 166, "similar_positions": 27, "identity": "80.98%" }, { "cls_id": "homologset.agr.MGI:1860085", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9JHN8-1", "uniprot_id": "WHR1_MOUSE", "id": "Q9JHN8-1", "name": "Winged helix repair factor 1", "aln": "MNRKRRLLASEAFGVKRRRAPGPVRADPLRTRAGSAREAIEELVKLFPRGLFEDALPPIALRSQVYSLVPDRTVADLQLKELQELGEIRIIQLGFDLDAHGIVFTEDYRTRVLKACDGRPCAGAVQKFLASVLPACGDLSFQQDQMTQTYGFRDPEITQLVNAGVLTVRDAGSWWLAVPGAGRFIKCFVKGRQAVLSMVRKAKYRELALSELLGRRAPLAVRLGLAYHVHDLIGAQLVDCVPTTSGTLLRLPDT--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8I5ZJ96-1", "uniprot_id": "A0A8I5ZJ96_RAT", "id": "A0A8I5ZJ96-1", "name": "", "aln": "MNRKRRLLASEVFGVKRRRVPGPVRADPLRAEAGSAREAIEELVQLFPRGLFEDALPPIALRTQVYSLVPDRTVADLQLKELQDRGEIQVIQLGFDLDAHGIVFTEDYRTRVLKACDGRPCAGAVQKFLASVLPACGDLSFQQDQMTQTYGFRDSEITHLVNAGVLTVRDAGSWWLAVPGAGRFIKCFVKGRQAVLSMVRKAKYRELPLSELLGRRVPSAVRLGLAYHVHDLIGAQLVDCVPTTSGTLLRLPDT--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P49842-4", "uniprot_id": "WHR1_HUMAN", "id": "P49842-4", "name": "Winged helix repair factor 1", "aln": "MSWKRHHLIPETFGVKRRRKRGPVESDPLRGEPGSARAAVSELMQLFPRGLFEDALPPIVLRSQVYSLVPDRTVADRQLKELQEQGEIRIVQLGFDLDAHGIIFTEDYRTRVLKACDGRPYAGAVQKFLASVLPACGDLSFQQDQMTQTFGFRDSEITHLVNAGVLTVRDAGSWWLAVPGAGRFIKYFVKGRQAVLSMVRKAKYRELLLSELLGRRAPVVVRLGLTYHVHDLIGAQLVDCISTTSGTLLRLPET--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A0R4IK86-1", "uniprot_id": "A0A0R4IK86_DANRE", "id": "A0A0R4IK86-1", "name": "", "aln": "MSRKR-ALIADTFCLKRRRCAADSLTGETHDGATDIRSSIQYLMTLFSRKLFNDTLPPVVLKHQLYSLHTDKTSVDKHVNDLRENGELLMFQLGFDSEAFALVFAEDYRAKVLQEEAGRKTLGTAEKFLDKLIPGCSDLSFNKDKMLKEFLFSDSEITQLVKSGLLTVRDAGSWWLSIPNSGRFIKYFIKGRKAVLNMVKKSKYSEILRTELEERRTTAQVKFQMKYHVHDIIGADLVECIQTTSGTVLRYVDGNN", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*. ** * .:.* :**** . :. : . . * ::. *: **.* **:*:***:.*: *:*** .*:* .* ::::*:: **: :.***** :*..::*:****::**: ** *:.:*** .::*.*.****::*:* : : * *.***:**::*:***********::*.:***** *:***:***.**:*:** *: :** **.. *:: : *****:***:**:*: *****:** : ", "identical_positions": 119, "similar_positions": 83, "identity": "46.48%" }, { "cls_id": "homologset.agr.MGI:1860086", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8IUI8-1", "uniprot_id": "CRLF3_HUMAN", "id": "Q8IUI8-1", "name": "Cytokine receptor-like factor 3", "aln": "----------MRGAMELEPELLLQEARENVEAAQSYR-------RELGHR-----LEGLREARR------------------------------------------QIKESASQTRDVLKQHFNDLKGTLGKLLDERLVTLLQEVDTIEQETIKPLDDCQKLIEHGVNTAEDLVREGEIAMLGGVGEENEKLWSFTKKASHIQLDSLPEVPLLVDVPCLSAQLDDSILNIVKDHIFKHGTVASRPPVQIEELIEKPGGIIVRWCKVDDDFTAQDYRLQFRKCTSNHFEDVYVGSETEFIVLHIDPNVDYQFRVCARGDGRQEWSPWSVPQIGHSTLVPHEWTAGFEGYSLSSRRNIALRNDSESS---GVLYSRAPTYFCGQTLTFRVETVGQPDRRDSIGVCAEKQDGYDSLQRDQAVCISTNGAVFVNGKEMTNQLPAVTSGSTVTFDIEAVTLGTTSNN---EGGHFKLRVTISSNNREVVFDWLLDQSCGSLYFGCSFFYPGWKVLVF", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9Z2L7-1", "uniprot_id": "CRLF3_MOUSE", "id": "Q9Z2L7-1", "name": "Cytokine receptor-like factor 3", "aln": "----------MKGAMEPEPEVLLQEARENVEAAQSYR-------RELGQR-----LQGLREAQR------------------------------------------QIKESASQTRDVLKQHFSDLKGTLGKLLDERLVTLLQEVDTIEQETIKPLDDCQKLIEHGVNTADDLVREGEIAILGGIEEESDKLWNFTKKASHIQLDSLPEVPLLVDVPCLSAQLDDSILNIVKDHIFKHGTVASRPPVQIEELIEKPGGIIVRWCKVDDDFTAQDYRLQFRKCTANHFEDVYVGSETEFIVLHIDPNVDYQFRVCARGDGRQEWSPWSVPQTGHSTLVPHEWTTGFEGYSLSSRRNIALRNDAESS---GVLYSSAPTYFCGQTLTFRVETVGQPDRRDSIGVCAERQNGYESLQRDQAVCISTNGAVFVNGKEMTNQLPAVTSGSTVTFDIEAVTLGTSNSH---EGGNAKLRVTISSNNREVVFDWLLEQACGPLYFGCSFFYPGWKVLVF", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8I6AEZ7-1", "uniprot_id": "A0A8I6AEZ7_RAT", "id": "A0A8I6AEZ7-1", "name": "Cytokine receptor-like factor 3", "aln": "RVCPPHTPTLHPHTPPPPPASVNQAAAGAGRGGQSRAGRRFRCARPLGVARGSRAQSGIRRAARPDEGRDGAGARGAAAGSPGERGGGAELPAGARPAAAGAAGGAEIKESASQTRDVLKQHFSDLKGTLGKLLDERLVTLLQEVDTIEQETIKPLDDCQKLIEHGVNTADDLVREGETAILGGIEEQNDKLWNFTKKASHIQLDSLPEVPLLVDVPCLSAQLDDSILNIVKDHIFKHGAVASRPPVQIEELVEKPGGIVVRWCKVDDDFTAQDYRLQFRKCPANPFEDVYVGSETEFIVLHIDPNVDYQFRVCARGDGRQEWSPWSVPQTGHSTLVPHEWTTGFEGYSLSSRRNIALRNDAESA---GVLYSSAPTYFCGQTLTFRVETVGQPDRRDSIGVCAEKQNGYESLQRDQAVCISTNGAVFVNGKEMTNQLPAVTSGSTVTFDIEAVTLGPCNNN---EGGNVKLRVTISSSNREVVFDWLLEQSCGSLYFGCSFFYPGWKVLVF", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q568M3-1", "uniprot_id": "CRLF3_DANRE", "id": "Q568M3-1", "name": "Cytokine receptor-like factor 3", "aln": "--------------MSIEAEALLQEAKESIEAAQNYR-------SELQQR-----LHGLSQARK------------------------------------------QVRGSASQTRKALQRHFQELQTAVSRLLIDRLNGLLQEVDNIELDSVSPLDDCQKLIEHGVSTADELLREGEAAIRCSINETEDKLGSFTKKALQIQLDSLPEVPSLVDVPCLSAQLDDSLLHMFRAHVARHGSVASHPPVQIEELVERPGGVLVRWCKVDDDFSPQDYRLQFRRSNSSQYEDAYIGKDTEFLVLHLDPHVDHLFRVCARGEGRTEWSPWSIPQTGYTTLAPHEWCPGVDGYILSSRKNIAMRSDSSAPGHGGVLYSNSPTYFCGQTLTFKITAAGQTDKRDSLGVCADSRTDTDSLQRDQAVCISTNGAVFVNGKEMTNQLPAITVGSSVTFDMEVVSLFPVNNNNPSDGGNFKLRVTIGSGNREVVFDWLLDQVLDSLFFGCSFTHPGWKVLVF", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . : * * ...*. * *: .* : ::: ******..*::**.:*: ::.:** :** ******.** :::.*************.**::*:**** *: .: * .:** .***** :********** **************:*::.: *: :**:***:********:*:***::**********:.********:. :. :**.*:*.:***:***:**:**: *******:** ******:** *::**.**** .*.:** ****:***:*.*:.:. ***** :***********:: :.**.*:***:****: : . :*****************************:* **:****:*.*:* . ..: :**: ******.*.**********:* ..*:***** :********", "identical_positions": 267, "similar_positions": 113, "identity": "52.15%" }, { "cls_id": "homologset.agr.MGI:1860093", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q5BJN1-1", "uniprot_id": "Q5BJN1_RAT", "id": "Q5BJN1-1", "name": "START domain-containing protein 10", "aln": "MMKGPRAAPGRPGSGGSGAGGRARTPAPARPGREARTGPRKVASASAAAPTLSEPPRRTQESRTRTRAPGLPTLSMEKPAASTEPQGPRPALGRESVQVPDDQDFRSFRSECEAEVGWNLTYSKAGVSVWVQAVEMDRTLHKIKCRMECCDVPAETLYDVLHDIEYRKKWDSNVIETFDIARLTVNADVGYYSWRCPKPLKNRDVITLRSWLPMGADYIIMNYSVKHPKYPPRKDLVRAVSIQTGYLIQSTGPKSCVITYLAQVDPKGSLPKWVVNKSSQFLAPKAMKKMYKACIKYPEWKQKHQPHFKPWLHPEQSPLPSLALSELSVQHADSLENIDESAVTESREERAGGAG-EGSDDDTSLT", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9JMD3-1", "uniprot_id": "STA10_MOUSE", "id": "Q9JMD3-1", "name": "START domain-containing protein 10", "aln": "---------------------------------------------------------------------------MEKPAASTEPQGSRPALGRESVQVPDDQDFRSFRSECEAEVGWNLTYSKAGVSVWVQAVEMDRTLHKIKCRMECCDVPAETLYDVLHDIEYRKKWDSNVIETFDIARLTVNADVGYYSWRCPKPLKNRDVITLRSWLPMGADYIIMNYSVKHPKYPPRKDLVRAVSIQTGYLIQSTGPKSCVITYLAQVDPKGSLPKWVVNKSSQFLAPKAMKKMYKACIKYPEWKQKHQPHFKPWLHPEQSPLPSLALSELSVQHADSLENIDESAVTESREERAGGAGGEGSDDDTSLT", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9Y365-1", "uniprot_id": "STA10_HUMAN", "id": "Q9Y365-1", "name": "START domain-containing protein 10", "aln": "---------------------------------------------------------------------------MEKLAASTEPQGPRPVLGRESVQVPDDQDFRSFRSECEAEVGWNLTYSRAGVSVWVQAVEMDRTLHKIKCRMECCDVPAETLYDVLHDIEYRKKWDSNVIETFDIARLTVNADVGYYSWRCPKPLKNRDVITLRSWLPMGADYIIMNYSVKHPKYPPRKDLVRAVSIQTGYLIQSTGPKSCVITYLAQVDPKGSLPKWVVNKSSQFLAPKAMKKMYKACLKYPEWKQKHLPHFKPWLHPEQSPLPSLALSELSVQHADSLENIDESAVAESREERMGGAGGEGSDDDTSLT", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AB40EB46-1", "uniprot_id": "A0AB40EB46_DANRE", "id": "A0AB40EB46-1", "name": "START domain-containing protein 10", "aln": "---------------------------------------------------------------------------MMK-------------TGDEEVLIPDDRAFSRFKHECEAEAGWTVTHNKSNICVWIQLLEEDKSLHKIKCRMTCKDIPAETMYDVLHDIEYRRKWDANVIETFDIGKLTVNADVGYYSWKCPKPLKNRDVITLRSWLPMGNDYIIMNYSVKHSKYPPKKDLVRAVSIQTGYLIQRTGPSSCTLTYLAQVDPKGSLPKWVVNKSSQLLAPKAMKRISKACARYPEWKQKHSPGFKPWLFPEQNPLSSIPMSELSIQHAESLENIDESALSESRDERA-----EHSDEDNANN", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * * * *.* :***: * *: *****.**.:*:.::.:.**:* :* *::******** * *:****:**********:***:********.:************:******************** ***********.****:**************** ***.**.:**********************:*******:: *** :******** * *****.***.**.*:.:****:***:*********::***:** * **:*.: .", "identical_positions": 203, "similar_positions": 49, "identity": "55.46%" }, { "cls_id": "homologset.agr.MGI:1860103", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9JIF3-1", "uniprot_id": "SL2A8_MOUSE", "id": "Q9JIF3-1", "name": "Solute carrier family 2, facilitated glucose transporter member 8", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSPEDPQETQPLLRPPEARTPRGRR---------------------------------------------------------------------------------------------------------------------------------------------------VFLASFAAALGPLSFGFALGYSS---PAIPSLRRT-----APPALRLGDNAASWFGAVVTLGAAAGGILGGWLLDRAGRKLSLLLCTVPFVTGFAVITAARD-VWMLLGGRLLTGLACGVASLVAPVYISEIAYPAVRGLLGSCVQLMVVTGILLAYVAG-------WVLEWRWLAVLGCVPPTLMLLLMCYMPETPRFLLTQHQYQEAMAALRF--LWGSEEGWE-------------EPPVGAEHQGFQLALLRRPGIYKPLIIGISLMVFQQLSGVNAIMFYANSIFEEAKF-KDSSLASVTVGIIQVLFTAVAALIMDRAGRRLLLALSGVIMVFSMSAFGTYFKLTQSLPSNSSHVG-LVPIAAEPVDVQVGLAWLAVGSMCLFIAGFAVGWGPIPWLLMSEIFPLHVKGVATGICVLTNWFMAFLVTKEFSSVMEMLRPYGAFWLTAAFCALSVLFTLTVVPETKGRTLEQVTAHFEGR----------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9JJZ1-1", "uniprot_id": "SL2A8_RAT", "id": "Q9JJZ1-1", "name": "Solute carrier family 2, facilitated glucose transporter member 8", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSPEDPQETQPLLRSPGARAPGGRR---------------------------------------------------------------------------------------------------------------------------------------------------VFLATFAAALGPLSFGFALGYSS---PAIPSLRRT-----APPALRLGDTAASWFGAVVTLGAAAGGVLGGWLLDRAGRKLSLLLCTVPFVTGFAVITAARD-VWMLLGGRLLTGLACGVASLVAPVYISEIAYPAVRGLLGSCVQLMVVTGILLAYVAG-------WVLEWRWLAVLGCVPPTLMLLLMCYMPETPRFLLTQHQYQEAMAALRF--LWGSEEGWE-------------EPPVGAEHQGFQLAMLRRPGVHKPLIIGICLMVFQQLSGVNAIMFYANTIFEEAKF-KDSSLASVTVGIIQVLFTAVAALIMDRAGRKLLLALSGVIMVFSMSAFGTYFKLTQSGPSNSSHVGLLVPISAEPADVHLGLAWLAVGSMCLFIAGFAVGWGPIPWLLMSEIFPLHIKGVATGVCVLTNWFMAFLVTKEFNSIMEILRPYGAFWLTAAFCILSVLFTLTFVPETKGRTLEQITAHFEGR----------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9NY64-1", "uniprot_id": "SL2A8_HUMAN", "id": "Q9NY64-1", "name": "Solute carrier family 2, facilitated glucose transporter member 8", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MTPEDPEETQPLLGPPGGSAPRGRR---------------------------------------------------------------------------------------------------------------------------------------------------VFLAAFAAALGPLSFGFALGYSS---PAIPSLQRA-----APPAPRLDDAAASWFGAVVTLGAAAGGVLGGWLVDRAGRKLSLLLCSVPFVAGFAVITAAQD-VWMLLGGRLLTGLACGVASLVAPVYISEIAYPAVRGLLGSCVQLMVVVGILLAYLAG-------WVLEWRWLAVLGCVPPSLMLLLMCFMPETPRFLLTQHRRQEAMAALRF--LWGSEQGWE-------------DPPIGAEQS-FHLALLRQPGIYKPFIIGVSLMAFQQLSGVNAVMFYAETIFEEAKF-KDSSLASVVVGVIQVLFTAVAALIMDRAGRRLLLVLSGVVMVFSTSAFGAYFKLTQGGPGNSSHVAISAPVSAQPVDASVGLAWLAVGSMCLFIAGFAVGWGPIPWLLMSEIFPLHVKGVATGICVLTNWLMAFLVTKEFSSLMEVLRPYGAFWLASAFCIFSVLFTLFCVPETKGKTLEQITAHFEGR----------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8MKK4-1", "uniprot_id": "TRE12_DROME", "id": "Q8MKK4-1", "name": "Trehalose transporter 1-like protein", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MKILMRADTHVSFSVP-----ADGLKAN-----------------------------------------------------------------------------------------------------------------------------------------------FTFSQVLAALSVSLCSLVVGFVSAYTS---PALVSMTDR-----TITSFEVTKDAGSWVGGIMPLAALAGGITGGPLIEYLGRRSTILATAVPFIVSSLLIACAVN-VIMILCGRFLTGFCVGIASLSLPVYLGETLQPEVRGTLGLLPTALGNIGILVCYVAG-------SFMNWSMLAFLGAALPVPFLILMIIIPETPRWFVNRGQEERARKALKW--LRGKEADVEPELKEL----MQSQADADRQATQNTCLELFKRNNLKPLSISLGLMFFQQFSGINAVIFYTVQIFKDAGSTIDSNLSTIIVGVVNFFATFMGIILIDRLGRKILLYVSDIAMIVTLSILGGFFYCKA-HGPDVSHLG-----------------WLPLTCFVIYILGFSLGFGPIPWLMMGEILPAKIRGPAASVVTAFNWFCTFVVTKTFQDLTVAMGAHGAFWLFGAICIVGLFFVIIFVPETRGKSLEEIERKMMGRVP-MSSVVNIKPFPFNM-----------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "A1Z8N1-1", "uniprot_id": "TRE11_DROME", "id": "A1Z8N1-1", "name": "Trehalose transporter 1", "aln": "MSGRDNRGAGGGGGGHQPLSNAMGKLKEKLTRVGDELGYHRVESNLSTSNTATSLDTILPEDPFLFPQVSPQRHPQNTVRTQRLLEDEPPLSFRPLLEDDDINEPPTQQQQRTPLRASGSLELTPLPPPPTSLEIREHRDRQQRGAQGDELQRSKQSLKGSRVSFERRDTGNSNTNSNKAAESSDEDSFEEKRTGFQQQKATSVDHKGILKDLKHILANDNRRQFQAKKHVSLDVKGTRFLQDLLKESSSEEEFHKTRREFQGRKHQSLDPRVTFKLDKVLQGSSTDSDEEGEDAEHKRLIHRPKDITKPVIIDLKDLESESDEDFLTSRQHFQQQRSISTDSRKSRRLYEMDEMDNKRGENIRHAVPFVRQITEDGKPKLEVYRPTTNPIYIWTQVLAALSVSLGSLVVGFVSAYTS---PALVSMTDR-----NITSFEVTQDAGSWVGGIMPLAGLAGGIAGGPLIEYLGRRNTILATAVPFIVSSLLIACAVN-VAMVLCGRFLAGFCVGIASLSLPVYLGETVQPEVRGTLGLLPTAFGNIGILLCFVAG-------SFMNWSMLAFLGAALPVPFLILMFLIPETPRWFVGRGLEERARKALKW--LRGKEADVEPELKGL----MRSQADADRQASRNTMLELLKLNNLKPLSISLGLMFFQQFSGINAVIFYTVQIFKDAGSTIDGNLCTIIVGIVNFLATFIGIVLIDRAGRKILLYVSDIAMVLTLFVLGGFFYCKT-YGPDVSHLG-----------------WLPLTCFVIYILGFSLGFGPIPWLMMGEILPAKIRGSAASVATAFNWFCTFVVTKTFQDLTVAMGAHGAFWLFGAICFVGLFFVIIYVPETQGKTLEDIERKMMGRVRRMSSVANIKPLSFNM-----------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VU17-1", "uniprot_id": "Q9VU17_DROME", "id": "Q9VU17-1", "name": "", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSTASSSNSSGEEANKKSGSNNEESSHLLESAENGAKYGSRQPVKIVKASDNGRTSSTPHDQENLLGNMVHTSTSNNS-----------------------------------------------------------------------------------------------------------------------------------------------QKWPQYVAALAAAGGAFAAGTVLGWTS---PAETEIVDRG----EGYDFPVDKDQFSWVGSAMTLGAACVCIPIGFLINMIGRKWTMLFLVLPFILGWTMLIWAVN-VSMLYASRFILGIAGGAFCVTAPMYTGEIAQKEIRGTLGSFFQLMITIGILFVYAVG-------AGVKIFWLSIICGILPLIFGAIFFFMPESPTYLVSKDRSENAIKSIQW--LRGKEYDYEPELAEL----RETDRETKANKVN-VWAALNRPVTRKALAISMGLMFFQQVCGINAVIFYASRIFLEANTGIEAEWATILIGIMQVVATFVSTLVVDKLGRRILLLASGISMAISTTAIGVYFFLQKQDAAQVVSLG-----------------WLPVASLCLFIIMFSIGYGPVPWLMMGELFATDIKGFAGSLAGTSNWLLAFVVTKTFVNLNDGLGIGGTFWLFAGLTVVGVIFVYFAVPETKGKSLNEIQQELAGNRSTPQAIPAEK-----------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "A8JQU1-1", "uniprot_id": "A8JQU1_DROME", "id": "A8JQU1-1", "name": "Major facilitator superfamily (MFS) profile domain-containing protein", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------MDSEKVVRAMARWWQTVSQEDGD----------------SRNPITYDLLQENQSKTSKTRQYVAAMIICLGAVAAGTA-----------------------------------------------------------------------------------------------------------------------------------------------LSWTSPVFPQISAGNESSFNSTTGGIS---NSTSNEND----------IRLTDSQKTLVGSMLPFGALFGALPSGYIADRIGRRYTAMVMDIPFILAWITLSFANS-VGWLYLGRFLIGIATGSFCVVAPMYISEIAETSIRGSLGTLFQLLLTIGILFIYVVG-------ALVSWKTLSLLCLIIPILLLVGLFIVPETPVYLLKNGKRSEANRALKW--LWG-DYCNTSNAIQA----IQNDLDQTGVDAS-VKDLFSNRASRNGMVISVLLMVFQQFSGINAVIFFMNEIFESSST-LNPNVCTIVVGVVQVIMTLASSLLIEKAGRKILLIFSSTIMTVCLAMLGAYNTINR-HTDLSQSIG-----------------WLPLLCIVLFIVSFSVGYGPIPWMMMGELFMPDVKGIAVSLSVMMNWVCVSLVTWLFGVLNAG-GADVPFWFFSAWMGVATAYVAIALQETKGKSASQIQSWLSGR----------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P39003-1", "uniprot_id": "HXT6_YEAST", "id": "P39003-1", "name": "High-affinity hexose transporter HXT6", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSQDAAIAEQTPVEH-----LSAVDSASHSVLSTPSNKAERDEIKAYGE-GEEHEPVVEIP-----KRPASAY-------------------------------------------------------------------------------------------------------------------------------------------------VTVSIMCIMIAFGGFVFGWDTGTISGFINQTDFIRRFG-MKHKDGTNYLSKVRTGLIVSIFNIGCAIGGIILSKLGDMYGRKVGLIVVVVIYIIGIIIQIASINKWYQYFIGRIISGLGVGGIAVLSPMLISEVSPKHLRGTLVSCYQLMITAGIFLGYCTNFGTKNYSNSVQWRVPLGLCFAWALFMIGGMTFVPESPRYLAEVGKIEEAKRSIAV--SNKVAVDDPSVLAEVEAVLAGVEAEKLAGNASWGELFSSKTKVLQRLIMGAMIQSLQQLTGDNYFFYYGTTIFKAVGL-SDSFETSIVLGIVNFASTFVGIYVVERYGRRTCLLWGAASMTACMVVYASVGVTRLWPNGQDQPSS-------------KGAGNCMIVFACFYIFCFATTWAPIPYVVVSETFPLRVKSKAMSIATAANWLWGFLIG-FFTPFITGAINFYYGYVFMGCLVFMFFYVLLVVPETKGLTLEEVNTMWEEGVLPWKSASWVPPSRRGANYDAEEMAHDDKPLYKRMFSTK-", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P39004-1", "uniprot_id": "HXT7_YEAST", "id": "P39004-1", "name": "High-affinity hexose transporter HXT7", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSQDAAIAEQTPVEH-----LSAVDSASHSVLSTPSNKAERDEIKAYGE-GEEHEPVVEIP-----KRPASAY-------------------------------------------------------------------------------------------------------------------------------------------------VTVSIMCIMIAFGGFVFGWDTGTISGFINQTDFIRRFG-MKHKDGTNYLSKVRTGLIVSIFNIGCAIGGIILSKLGDMYGRKVGLIVVVVIYIIGIIIQIASINKWYQYFIGRIISGLGVGGIAVLSPMLISEVSPKHLRGTLVSCYQLMITAGIFLGYCTNFGTKNYSNSVQWRVPLGLCFAWALFMIGGMTFVPESPRYLAEVGKIEEAKRSIAV--SNKVAVDDPSVLAEVEAVLAGVEAEKLAGNASWGELFSSKTKVLQRLIMGAMIQSLQQLTGDNYFFYYGTTIFKAVGL-SDSFETSIVLGIVNFASTFVGIYVVERYGRRTCLLWGAASMTACMVVYASVGVTRLWPNGQDQPSS-------------KGAGNCMIVFACFYIFCFATTWAPIPYVVVSETFPLRVKSKAMSIATAANWLWGFLIG-FFTPFITGAINFYYGYVFMGCLVFMFFYVLLVVPETKGLTLEEVNTMWEEGVLPWKSASWVPPSRRGANYDAEEMTHDDKPLYKRMFSTK-", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P32467-1", "uniprot_id": "HXT4_YEAST", "id": "P32467-1", "name": "Low-affinity glucose transporter HXT4", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSEEAAYQEDTAVQNTPADALSPVESDSNSALSTPSNKAERDDMKDFDENHEESNNYVEIP-----KKPASAY-------------------------------------------------------------------------------------------------------------------------------------------------VTVSICCLMVAFGGFVFGWDTGTISGFVAQTDFIRRFG-MKHHDGTYYLSKVRTGLIVSIFNIGCAIGGIILAKLGDMYGRKMGLIVVVVIYIIGIIIQIASINKWYQYFIGRIISGLGVGGIAVLSPMLISEVSPKHIRGTLVSCYQLMITLGIFLGYCTNYGTKTYTNSVQWRVPLGLGFAWALFMIGGMTFVPESPRYLVEVGKIEEAKRSIAL--SNKVSADDPAVMAEVEVVQATVEAEKLAGNASWGEIFSTKTKVFQRLIMGAMIQSLQQLTGDNYFFYYGTTVFTAVGL-EDSFETSIVLGIVNFASTFVGIFLVERYGRRRCLLWGAASMTACMVVFASVGVTRLWPNGKKNGSS-------------KGAGNCMIVFTCFYLFCFATTWAPIPFVVNSETFPLRVKSKCMAIAQACNWIWGFLIG-FFTPFISGAIDFYYGYVFMGCLVFSYFYVFFFVPETKGLTLEEVNTLWEEGVLPWKSPSWVPPNKRGTDYNADDLMHDDQPFYKKMFGKK-", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P32466-1", "uniprot_id": "HXT3_YEAST", "id": "P32466-1", "name": "Low-affinity glucose transporter HXT3", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MNSTPDLISPQKSSENS----NADLPSNSSQVMNMPEEKGVQDDFQ------AEADQVLTNP-----NTGKGAY-------------------------------------------------------------------------------------------------------------------------------------------------VTVSICCVMVAFGGFVFGWDTGTISGFVAQTDFLRRFG-MKHKDGSYYLSKVRTGLIVSIFNIGCAIGGIILAKLGDMYGRKMGLIVVVVIYIIGIIIQIASINKWYQYFIGRIISGLGVGGIAVLSPMLISEVAPKEMRGTLVSCYQLMITLGIFLGYCTNFGTKNYSNSVQWRVPLGLCFAWALFMIGGMTFVPESPRYLVEAGQIDEARASLSK--VNKVAPDHPFIQQELEVIEASVEEARAAGSASWGELFTGKPAMFKRTMMGIMIQSLQQLTGDNYFFYYGTTVFNAVGM-SDSFETSIVFGVVNFFSTCCSLYTVDRFGRRNCLLYGAIGMVCCYVVYASVGVTRLWPNGEGNGSS-------------KGAGNCMIVFACFYIFCFATTWAPIAYVVISETFPLRVKSKAMSIATAANWLWGFLIG-FFTPFITGAINFYYGYVFMGCMVFAYFYVFFFVPETKGLTLEEVNDMYAEGVLPWKSASWVPTSQRGANYDADALMHDDQPFYKKMFGKK-", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P38695-1", "uniprot_id": "HXT5_YEAST", "id": "P38695-1", "name": "Probable glucose transporter HXT5", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------MSELENAHQGPLEGSATVSTNSNSYNEKS-GNSTAPGTAGYNDNLAQAKPVSSYISHEGPPKDELEELQKEVDKQLEKKSKSDL-------------------------------------------------------------------------------------------------------------------------------------------------LFVSVCCLMVAFGGFVFGWDTGTISGFVRQTDFIRRFG-STRANGTTYLSDVRTGLMVSIFNIGCAIGGIVLSKLGDMYGRKIGLMTVVVIYSIGIIIQIASIDKWYQYFIGRIISGLGVGGITVLAPMLISEVSPKQLRGTLVSCYQLMITFGIFLGYCTNFGTKNYSNSVQWRVPLGLCFAWSIFMIVGMTFVPESPRYLVEVGKIEEAKRSLAR--ANKTTEDSPLVTLEMENYQSSIEAERLAGSASWGELVTGKPQMFRRTLMGMMIQSLQQLTGDNYFFYYGTTIFQAVGL-EDSFETAIVLGVVNFVSTFFSLYTVDRFGRRNCLLWGCVGMICCYVVYASVGVTRLWPNGQDQPSS-------------KGAGNCMIVFACFYIFCFATTWAPVAYVLISESYPLRVRGKAMSIASACNWIWGFLIS-FFTPFITSAINFYYGYVFMGCMVFAYFYVFFFVPETKGLTLEEVNEMYEENVLPWKSTKWIPPSRRTTDYDLDATRNDPRPFYKRMFTKEK", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P40886-1", "uniprot_id": "HXT8_YEAST", "id": "P40886-1", "name": "Hexose transporter HXT8", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MTDRKTNLPEEPIFEEAEDDGCPSIENSSHLSVPTVEENKD-----FSEYNGEEAEEVVVPE------KPASAY-------------------------------------------------------------------------------------------------------------------------------------------------ATVSIMCLCMAFGGFMSGWDTGTISGFVNQTDFLRRFGNYSHSKNTYYLSNVRTGLIVSIFNVGSAIGCLFLSKLGDIYGRCMGLIIVIVVYMVGIVIQIASIDKWYQYFIGRIIAGIGAGSISVLAPMLISETAPKHIRGTLLACWQLMVTFAIFLGYCTNYGTKTYSNSVQWRVPLGLCFAWAIIMIGGMTFVPESPRFLVQVGKIEQAKASFAK--SNKLSVDDPAVVAEIDLLVAGVEAEEAMGTASWKELFSRKTKVFQRLTMTVMINSLQQLTGDNYFFYYGTTIFKSVGM-NDSFETSIVLGIVNFASCFFSLYSVDKLGRRRCLLLGAATMTACMVIYASVGVTRLYPNGKSEPSS-------------KGAGNCTIVFTCFYIFCFSCTWGPVCYVIISETFPLRVRSKCMSVATAANLLWGFLIG-FFTPFITSAINFYYGYVFMGCLAFSYFYVFFFVPETKGLTLEEVDEMWMDGVLPWKSESWVPASRRDGDYDNEKLQHDEKPFYKRMF----", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P13181-1", "uniprot_id": "GAL2_YEAST", "id": "P13181-1", "name": "Galactose transporter", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MAVEENNMPVVSQQPQAGEDVISSLSKDSHLSAQSQKYSNDELKAGESGSEGSQSVPIEIPK------KPMSEY-------------------------------------------------------------------------------------------------------------------------------------------------VTVSLLCLCVAFGGFMFGWDTGTISGFVVQTDFLRRFG-MKHKDGTHYLSNVRTGLIVAIFNIGCAFGGIILSKGGDMYGRKKGLSIVVSVYIVGIIIQIASINKWYQYFIGRIISGLGVGGIAVLCPMLISEIAPKHLRGTLVSCYQLMITAGIFLGYCTNYGTKSYSNSVQWRVPLGLCFAWSLFMIGALTLVPESPRYLCEVNKVEDAKRSIAK--SNKVSPEDPAVQAELDLIMAGIEAEKLAGNASWGELFSTKTKVFQRLLMGVFVQMFQQLTGNNYFFYYGTVIFKSVGL-DDSFETSIVIGVVNFASTFFSLWTVENLGHRKCLLLGAATMMACMVIYASVGVTRLYPHGKSQPSS-------------KGAGNCMIVFTCFYIFCYATTWAPVAWVITAESFPLRVKSKCMALASASNWVWGFLIA-FFTPFITSAINFYYGYVFMGCLVAMFFYVFFFVPETKGLSLEEIQELWEEGVLPWKSEGWIPSSRRGNNYDLEDLQHDDKPWYKAMLE---", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P43581-1", "uniprot_id": "HXT10_YEAST", "id": "P43581-1", "name": "Hexose transporter HXT10", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MVSSS---------VSILGTSAKASTSLSR-------KDEIKLTPETREASLDIP-----YKPIIAY-------------------------------------------------------------------------------------------------------------------------------------------------WTVMGLCLMIAFGGFIFGWDTGTISGFINQTDFKRRFG-ELQRDGSFQLSDVRTGLIVGIFNIGCALGGLTLGRLGDIYGRKIGLMCVILVYVVGIVIQIASSDKWYQYFIGRIVSGMGVGGVAVLSPTLISEISPKHLRGTCVSFYQLMITLGIFLGYCTNYGTKKYSNSIQWRVPLGLCFAWAIFMVIGMVMVPESPRYLVEKGKYEEARRSLAK--SNKVTVTDPGVVFEFDTIVANMELERAVGNASWHELFSNKGAILPRVIMGIVIQSLQQLTGCNYFFYYGTTIFNAVGM-QDSFETSIVLGAVNFASTFVALYIVDKFGRRKCLLWGSASMAICFVIFATVGVTRLWPQGKDQPSS-------------QSAGNVMIVFTCFFIFSFAITWAPIAYVIVAETYPLRVKNRAMAIAVGANWMWGFLIG-FFTPFITRSIGFSYGYVFMGCLIFSYFYVFFFVCETKGLTLEEVNEMYEERIKPWKSGGWIPSSRRTPQPTSSTPLVIVDSK---------", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P23585-1", "uniprot_id": "HXT2_YEAST", "id": "P23585-1", "name": "High-affinity glucose transporter HXT2", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSEFA---------TSRVESGSQQTSIHSTPIVQKLETDESPIQTKSEYTNAELP-----AKPIAAY-------------------------------------------------------------------------------------------------------------------------------------------------WTVICLCLMIAFGGFVFGWDTGTISGFVNQTDFKRRFG-QMKSDGTYYLSDVRTGLIVGIFNIGCAFGGLTLGRLGDMYGRRIGLMCVVLVYIVGIVIQIASSDKWYQYFIGRIISGMGVGGIAVLSPTLISETAPKHIRGTCVSFYQLMITLGIFLGYCTNYGTKDYSNSVQWRVPLGLNFAFAIFMIAGMLMVPESPRFLVEKGRYEDAKRSLAK--SNKVTIEDPSIVAEMDTIMANVETERLAGNASWGELFSNKGAILPRVIMGIMIQSLQQLTGNNYFFYYGTTIFNAVGM-KDSFQTSIVLGIVNFASTFVALYTVDKFGRRKCLLGGSASMAICFVIFSTVGVTSLYPNGKDQPSS-------------KAAGNVMIVFTCLFIFFFAISWAPIAYVIVAESYPLRVKNRAMAIAVGANWIWGFLIG-FFTPFITSAIGFSYGYVFMGCLVFSFFYVFFFVCETKGLTLEEVNEMYVEGVKPWKSGSWISKEKRVSEE---------------------", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P54854-1", "uniprot_id": "HXT15_YEAST", "id": "P54854-1", "name": "Hexose transporter HXT15", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MASEQSSPEINA---------DNLNSSAADVHVQPPGEKEWSDGFYDKEVINGNTPDAPK--------RGFLGY-------------------------------------------------------------------------------------------------------------------------------------------------LIIYLLCYPVSFGGFLPGWDSGITAGFINMDNFKMNFGSYKHSTGEYYLSNVRMGLLVAMFSVGCSIGGVAFARLADTLGRRLAIVIVVLVYMVGAIIQISSNHKWYQYFVGKIIYGLGAGGCSVLCPMLLSEIAPTDLRGGLVSLYQLNMTFGIFLGYCSVYGTRKYSNTAQWRIPVGLCFLWALIIIVGMLLVPESPRYLIECERHEEACVSIAK--INKVSPEDPWVLKQADEINAGVLAQRELGEASWKELFSVKTKVLQRLITGILVQTFLQLTGENYFFFYGTTIFKSVGL-TDGFETSIVLGTVNFFSTIIAVMVVDKIGRRKCLLFGAASMMACMVIFASIGVKCLYPHGQDGPSS-------------KGAGNAMIVFTCFYIFCFATTWAPVAYIVVAESFPSKVKSKAMSISTAFNWLWQFLIG-FFTPFITGSIHFYYGYVFVGCLVAMFLYVFFFLPETIGLSLEEIQLLYEEGIKPWKSASWVPPSRRGASSRETEAKKKSWKEVLKFPKSFN", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P47185-1", "uniprot_id": "HXT16_YEAST", "id": "P47185-1", "name": "Hexose transporter HXT16", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MASEQSSPEINA---------DNLNSSAADVHVQPPGEKEWSDGFYDKEVINGNTPDAPK--------RGFLGY-------------------------------------------------------------------------------------------------------------------------------------------------LIIYLLCYPVSFGGFLPGWDSGITAGFINMDNFKMNFGSYKHSTGEYYLSNVRMGLLVAMFSVGCSIGGVAFARLADTLGRRLAIVIVVLVYMVGAIIQISSNHKWYQYFVGKIIYGLGAGGCSVLCPMLLSEIAPTDLRGGLVSLYQLNMTFGIFLGYCSVYGTRKYSNTAQWRIPVGLCFLWALIIIVGMLLVPESPRYLIECERHEEACVSIAK--IDKVSPEDPWVLKQADEINAGVLAQRELGEASWKELFSVKTKVLQRLITGILVQTFLQLTGENYFFFYGTTIFKSVGL-TDGFETSIVLGTVNFFSTIIAVMVVDKIGRRKCLLFGAASMMACMVIFASIGVKCLYPHGQDGPSS-------------KGAGNAMIVFTCFYIFCFATTWAPVAYIVVAESFPSKVKSKAMSISTAFNWLWQFLIG-FFTPFITGSIHFYYGYVFVGCLVAMFLYVFFFLPETIGLSLEETQLLYEEGIKPWKSASWVPPSRRGASSRETEAKKKSWKEVLKFPKSFN", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P39924-1", "uniprot_id": "HXT13_YEAST", "id": "P39924-1", "name": "Hexose transporter HXT13", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSSAQSSIDSDG---------DVR---DADIHVAPPVEKEWSDGFDDNEVINGDNVEPPK--------RGLIGY-------------------------------------------------------------------------------------------------------------------------------------------------LVIYLLCYPISFGGFLPGWDSGITAGFINMDNFKMNFGSYKHSTGEYYLSNVRMGLLVAMFSIGCAIGGLIFARLADTLGRRLAIVIVVLVYMVGAIIQISSNHKWYQYFVGKIIYGLGAGGCSVLCPMLLSEIAPTDLRGGLVSLYQLNMTFGIFLGYCSVYGTRKYDNTAQWRVPLGLCFLWALIIIIGMLLVPESPRYLIECERHEEARASIAK--INKVSPEDPWVLKQADEINAGVLAQRELGEASWKELFSVKTKVLQRLITGILVQTFLQLTGENYFFFYGTTIFKSVGL-TDGFETSIVLGTVNFFSTIIAVMVVDKIGRRKCLLFGAAGMMACMVIFASIGVKCLYPHGQDGPSS-------------KGAGNAMIVFTCFYIFCFATTWAPVAYIVVAESFPSKVKSRAMSISTACNWLWQFLIG-FFTPFITGSIHFYYGYVFVGCLVAMFLYVFFFLPETIGLSLEEIQLLYEEGIKPWKSASWVPPSRRGISSEESKTEKKDWKKFLKFSKNSD", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P53631-1", "uniprot_id": "HXT17_YEAST", "id": "P53631-1", "name": "Hexose transporter HXT17", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MQSSTESDR---------DIQDGPDADIHVAPPVEKEWSDGFDDNEVINGDNVEPPK--------RGLIGY-------------------------------------------------------------------------------------------------------------------------------------------------LVIYLLCYPISFGGFLPGWDSGITAGFINMDNFKMNFGSYKHSTGEYYLSNVRMGLLVAMFSIGCAIGGLIFARLADTLGRRLAIVIVVLVYMVGAIIQISSNHKWYQYFVGKIIYGLGAGGCSVLCPMLLSEIAPTDLRGGLVSLYQLNMTFGIFLGYCSVYGTRKYDNTAQWRVPLGLCFLWTLIIIIGMLLVPESPRYLIECERHEEARASIAK--INKVSPEDPWVLKQADEINAGVLAQRELGEASWKELFSVKTKVLQRLITGILVQTFLQLTGENYFFFYGTTIFKSVGL-TDGFETSIVLGTVNFFSTIIAVMVVDKIGRRKCLLFGAAGMMACMVIFASIGVKCLYPHGQDGPSS-------------KGAGNAMIVFTCFYIFCFATTWAPVAYIVVAESFPSKVKSRAMSISTACNWLWQFLIG-FFTPFITGSIHFYYGYVFVGCLVAMFLYVFFFLPETIGLSLEEIQLLYEEGIKPWKSASWVPPSRRGIPSEESKTEKKDWKKFLKFSKGSD", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "Q9VQP0-1", "uniprot_id": "Q9VQP0_DROME", "id": "Q9VQP0-1", "name": "Major facilitator superfamily (MFS) profile domain-containing protein", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MATFLKNSLLQQKTR--------------------------------------------------------------------------------------------------------------------------------------------------------------YQLLATVIVNIITFGHGVGVGWLS---PTLTKIQTAD----SPLDFEVNLAQISWLGSMLGLDSLCGNLTIAMLIERAGRKFCLYLMAGPYACIWILIYCASN-VYYLYAARFLCGFTGGAGYLVVPIFISEVADSNIRGALTSMVMLSVDLGILAGYILS-------TYLAYHVVPFLAIILPVAYFIANIMLPETAPYLLKKSQLAAAENSFRYYRNQRSAICEQTSKVNFEELRTAVLSQQTRNATPLSYKDLTTKPALKGFAASIVLSLGYQFSGVFSFINYMSDIFKASGSVVDVNTATIIIGLVQIVGVYTSTILVDIVGRRVLMLISTMGVGIGCIAFGCFTYLAKIYDLSDFN-------------------WLPLVLMIIICYVANIGLIGIFFLVLVELFPVKIRSLATSLSVIFLSLLVFGTLKLFPLMLHYWGISFTMWFSAASALLTFFYFWLFLQETKGKSMIED-----------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P53403-1", "uniprot_id": "GTR3_DROME", "id": "P53403-1", "name": "Glucose transporter type 3", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MRKGGIQDAEPVEPPQSSRKSGTWFAKRPSEMPERHVERAPVRQKINNVG--------------------------------------------------------------------------------------------------------------------------------------------------LYKATLYSNIGSFFFGIAVGWSGTAERSVMEQHSYS--------FQPTELQWSGVCILLTLGAALWCLPMGLMVRLLGCRRTILIQLLPNFLGWFLTVFARS-VPMLYAGRFFLGMCGGAHCVVVPIYNAEISTTKKRGAMGVVFEGACICGVIYSFAMS-------LFLELRIINFVNLG-LLALGPLQILMPESPAYYVDHGNIPRAEDSLRF--LRGQKYDTRREIDFLT----RDPTESEREVRQGPLLGFKYKKVRRSLARSLAIALLQKLCGALIFIFYGLNMLDCLRI---RREFGLILCLGLILGFLACFFLVDRLGRRPLLIFSSAGIVFVSIYLGLHFKVWMTMGLTVMS-------------------WIALFCIAIFVGCYTAGVGSLTWVLNAELLVRPMRPLGCSIVCAFNWLTAFFVICWFGSHGVKCQPYLF-LLFAIIASLILLFSLIYIPETKKLSSAKIQQRLGGLINRPAVITFTSSSDSSNA----------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . . . . . . : . * : .::. *: * : * .* ** .:: : : :**:. : * :: : :. * .: : :: : . . :: *:: : . : . : : : ::: * :: .: . * . : : ** : . ", "identical_positions": 16, "similar_positions": 62, "identity": "1.74%" }, { "cls_id": "homologset.agr.MGI:1860118", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "F1MAG8-1", "uniprot_id": "F1MAG8_RAT", "id": "F1MAG8-1", "name": "", "aln": "-MNANKDENPRPRSQD-LHLFHAGMMLIVTVLYLPVTET--SKQNIPRLKLTYKDLLLSNTCIPFLGSSEGLDFQTLLLDEERGILLLGAKDHVFLLNLVDLN---KNFKKIYWPAAKERVELCKLAGKDANTECANFIRVLQPYN-KTHVYVCGTGAFHPLCGYIDLGANKEELIFKLDMQNLESGRLKCPFDPQQPFASVMTDEH-------LYSGTASDFLGKDTAFTR-----SLGLMQDHHYIRTDISEHYWLNGAKFIGTFPIPDTYNPDDDKIYFFFRESSQEGSTSDRSILSRVGRVCKNDVGGQRSLINKWTTFLKARLVCSIPGSDGADTHFDELQDIYLLPTRDERNPVVYGVFTTTSSIFKGSAVCVYSMADIRAVFNGPYAHKESADHRWVQYDG-RIPYPRPGTCPSKTYDPLIKSTRDFPDDVISFIRRHPVMYKSVYPVAGAPTFKRINVDYRLTQIVVDHVVAEDGQYDVMFLGTDIGTVLKVVSISKEKWNMEEVVLEELQVFKHPTAILNMELSLKQQQLYVGSWDGLVQLSLHRCDTYGKACADCCLARDPYCAWDGNACSRYAPTSKRRARRQDVKYGDPITQCWDIEDSISHEAADEKVIFGIEFNSTFLECIPKSQQASVEWYIQ-RSGDEHREELKPDERIIKTDYGLLIRSLQKKDSGIYYCKAQEHTFIHTIVKLTLNVIENEQMENNQRAEYQEGQVKDLLAESRLRYKDYIQILSSPNFSLDQYCEQMWYREKRRQRNKGSAKWKHMQEMKKKRNRRHHRDLDELQRSVAT", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8BH34-1", "uniprot_id": "SEM3D_MOUSE", "id": "Q8BH34-1", "name": "Semaphorin-3D", "aln": "-MNVTKDENPRSRSQD-LHLFHAWMMLIMTVLFLPVTET--SKQNIPRLKLTYKDLLLSNTCIPFLGSSEGLDFQTLLLDEERGILLLGAKDHVFLLSLVDLN---KNFKKIYWPAAKERVELCKLAGKDANAECANFIRVLQPYN-KTHVYVCGTGAFHPLCGYIDLGANKEELIFKLDTHNLESGRLKCPFDPQQPFASVMTDEH-------LYSGTASDFLGKDTAFTR-----SLGLMQDHHSIRTDISEHHWLNGAKFIGTFPIPDTYNPDDDKIYFFFRESSQEGSTSDRSILSRVGRVCKNDVGGQRSLINKWTTFLKARLICSIPGSDGADTHFDELQDIYLLPTRDERNPVVYGVFTTTSSIFKGSAVCVYSMADIRAVFNGPYAHKESADHRWVQYDG-RIPYPRPGTCPSKTYDPLIKSTRDFPDDVISFIRRHPVMYKSVYPVAGAPTFKRINVDYRLTQIVVDHVVAEDGQYDVMFLGTDIGTVLKVVSISKEKWNMEEVVLEELQVFKHPTAILNMELSLKQQQLYVGSWDGLVQLSLHRCDTYGKACADCCLARDPYCAWDGNACSRYAPTSKRRARRQDVKYGDPITQCWDIEDSISHETADEKVIFGIEFNSTFLECIPKSQQASVEWYIQ-RSGDEHREELKPDERIIKTDYGLLIRSLQKKDSGMYYCKAQEHTFIHTIVKLTLNVIENEQMENTQRAEYQEGQVKDLLAESRLRYKDYIQILSSPNFSLDQYCEQMWYKEKRRQRNKGSPKWKHMQEMKKKRNRRHHRDLDELQRSVAT", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O95025-1", "uniprot_id": "SEM3D_HUMAN", "id": "O95025-1", "name": "Semaphorin-3D", "aln": "-MNANKDERLKARSQD-FHLFPALMMLSMTMLFLPVTGT--LKQNIPRLKLTYKDLLLSNSCIPFLGSSEGLDFQTLLLDEERGRLLLGAKDHIFLLSLVDLN---KNFKKIYWPAAKERVELCKLAGKDANTECANFIRVLQPYN-KTHIYVCGTGAFHPICGYIDLGVYKEDIIFKLDTHNLESGRLKCPFDPQQPFASVMTDEY-------LYSGTASDFLGKDTAFTR-----SLGPTHDHHYIRTDISEHYWLNGAKFIGTFFIPDTYNPDDDKIYFFFRESSQEGSTSDKTILSRVGRVCKNDVGGQRSLINKWTTFLKARLICSIPGSDGADTYFDELQDIYLLPTRDERNPVVYGVFTTTSSIFKGSAVCVYSMADIRAVFNGPYAHKESADHRWVQYDG-RIPYPRPGTCPSKTYDPLIKSTRDFPDDVISFIKRHSVMYKSVYPVAGGPTFKRINVDYRLTQIVVDHVIAEDGQYDVMFLGTDIGTVLKVVSISKEKWNMEEVVLEELQIFKHSSIILNMELSLKQQQLYIGSRDGLVQLSLHRCDTYGKACADCCLARDPYCAWDGNACSRYAPTSKRRARRQDVKYGDPITQCWDIEDSISHETADEKVIFGIEFNSTFLECIPKSQQATIKWYIQ-RSGDEHREELKPDERIIKTEYGLLIRSLQKKDSGMYYCKAQEHTFIHTIVKLTLNVIENEQMENTQRAEHEEGKVKDLLAESRLRYKDYIQILSSPNFSLDQYCEQMWHREKRRQRNKGGPKWKHMQEMKKKRNRRHHRDLDELPRAVAT", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9W6G6-1", "uniprot_id": "SEM3D_DANRE", "id": "Q9W6G6-1", "name": "Semaphorin-3D", "aln": "MKTAGEPDRRRQRRQVRTGRFSCAWWSTSVMLFFSLPEGNCMKESLPRVKLGYKDLIHSRSVVPFTGSSEGQHFQTVLLDEERSRLLLGAKDHVYLLDPDNIN---KHPKKLSWPASRDRVEMCILAGKNPLTECANFIRVLHSYN-RTHVYACGTGAFHPTCAFLEIKGHKEDRWLLLHSNTMESGRMKCPFDPNQPFASVLTDQY-------LYAGTASDFLGKDSTFTR-----SLGPPPHQQYIRTDISEDYWINEGKFISAHPISDTYNPDDDKIYFFFREASRDGSTTDKSVLSRVARICRNDVGGLRSLTNKWTTFLKARLVCSIPGPDGVDTHFDELQDIFLLPSRDEKNPMVYGVFTTTSSIFKGSAVCVYTMEDIRAAFNGPYAHKEGPDHRWVEYEG-RIPYPRPGTCPSRTYDPHIKTTKDFPDEVISFIRLHPLMYQSVHPMTGRPIFTRINTEYRLTQIIVDRVAAEDGQYAVMFLGTDMGSVLKVVSITQENWSSEEIILEELQVFKNPSPILNMEVSSKQQQLFVGGSDGLVQVSLHRCQIYGQGCAECCLARDPYCAWDGTQCSRYIPASKRRARRQDIKHGDPSSHCWDTEDVLGRN-VEEKVLYGVESNSSFLECVSKSQQALIRWFVL-KPGVDHRQEIKPDERVLITDRGLLIRWLQRGDAGSYFCTSQEHRFTRTLLHVSLHILDRGQINAHQPAIR-ESSENPAVTEPRQRYKDYLRMLSGPARSLDEYCETMWHREKK-QKQKG--KWKHVQELRKSRNRRHH------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q24323-1", "uniprot_id": "SEM2A_DROME", "id": "Q24323-1", "name": "Semaphorin-2A", "aln": "------MSLLQLSPLLALLLLLCSSVSETAADYENTWNFYYERPCCTGNDQGNNNYGKHGADHVREFNCGKLYYRTFHMNEDRDTLYVGAMDRVFRVNLQNISSSNCNRDVINLEPTRDDVVSCVSKGKSQIFDCKNHVRVIQSMDQGDRLYVCGTNAHNPKD--YVIYANLTHLPRSEYVIGVGLGIAKCPYDPLDNSTAIYVENGNPGGLPGLYSGTNAEFTKADTVIFRTDLYNTSAKRLEYKFKRTLKYDSKWLDKPNFVGSFDIG-------EYVYFFFRETAVEYINCGKAVYSRIARVCKKDVGGKNLLAHNWATYLKARLNCSISG--EFPFYFNEIQSVYQLPSDKSR---FFATFTTSTNGLIGSAVCSFHINEIQAAFNGKFKEQSSSNSAWLPVLNSRVPEPRPGTC--------VNDTSNLPDTVLNFIRSHPLMDKAVNHEHNNPVYYKRDLVFTKLVVDKIRIDILNQEYIVYYVGTNLGRIYKIVQYYRNGESLS-KLLDIFEVAPN-EAIQVMEISQTRKSLYIGTDHRIKQIDLAMCNRRYDNCFRC--VRDPYCGWDKEAN-------TCRPYELDLLQDVANETSDICDSSVLKKKIVVTYGQSVHLG-CFVKIPEVLKNEQVTWYHHSKDKGRYEIRYSPTKYIETTERGLVVVSVNEADGGRYDCHLGGSLLCSYNITVDAHRCTPPNKSN-----------------------DYQKIYSDWCHEFEKYKTAMKSWEKKQAQCSTRQNFSSNQHPNEIFRKPNV------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . : : . . : : . . :: : .. ::*. ::*:*. * :** *::: :. ::. : . : .::: * * **. :* *.:**::. : ::*.***.*.:* : . : * ***:** : ::: .:: **:** ::* *:.: * : . . : ** : *:: :*:.:. * : :******:: : . .::: **:.*:*::**** . * ::*:*:***** ***.* :*:*:*.:: **: ..: .:..***::. : ***** : : :*:*.*** : .:...: *: . *:* ****** :: * ::** *:.**: *.:* ::* . * : : : : : :: : :* * ::**::* : *:*. :: . . :*: ::: : * **:* .::.*::* . : *:.* *: . * * .*****.** . *. . *: . . . :. : :: . .:. . *:: :: : *: : :. . .* : : *: **:: ::. *.* * * : : : : : . ** :: *. .:::* * **: : . ::. *. .: .: : ", "identical_positions": 148, "similar_positions": 249, "identity": "18.52%" }, { "cls_id": "homologset.agr.MGI:1860130", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9EQD2-1", "uniprot_id": "NPFF2_RAT", "id": "Q9EQD2-1", "name": "Neuropeptide FF receptor 2", "aln": "---------------------------------------------------------------------------------------------------------------------------------MGKRWDSNSSGSWDHIWSGNDTQHPWYSDIN-ITYMN---------------------------------YYLHQPHVTAVFISSYFLIFFLCMVGNTVVCFVVIRNRYMHTVTNFFIFNLAISDLLVGIFCMPITLLDNIIAGWPFGSSMCKISGLVQGISVAASVFTLVAIAVDRFRCVVYPFKPKLTVKTAFVMIVIIWGLAITIMTPSAIMLHVQEEKYYRVRLSSHNKTSTVYWCREDWPN-QEMRRIYTTVLFATIYLAPLSLIVIMYARIGASLFKTSAHSTGKQRLEQWHVS-KKKQKVIKMLLTVALLFILSWLPLWTLMMLSDYADLSPNKLRVINIYVYPFAHWLAFCNSSVNPIIYGFFNENFRSGFQDAF--QFCQKKVKPQEAYGLRAKRNLDINTSGLLVHEP--------------------------ASQNPSGENLGCRKSADNPTQESLMEETGEATNSTET-------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q924H0-1", "uniprot_id": "NPFF2_MOUSE", "id": "Q924H0-1", "name": "Neuropeptide FF receptor 2", "aln": "---------------------------------------------------------------------------------------------------------------------------------MSEKWDSNSSESWNHIWSGNDTQHHWYSDIN-ITYVN---------------------------------YYLHQPQVAAVFISSYLLIFVLCMVGNTVVCFIVIRNRHMHTVTNFFILNLAISDLLVGIFCMPITLLDNIIAGWPFGSSMCKISGLVQGISVAASVFTLVAIAVDRFRCVVYPFKPKLTVKTAFVTIVIIWGLAIAIMTPSAIMLHVQEEKYYRVRLSSHNKTSTVYWCREDWPR-HEMRRIYTTVLFATIYLAPLSLIVIMYARIGASLFKTAAHCTGKQRPVQWHVS-KKKQKVIKMLLTVALLFILSWLPLWTLMMLSDYTDLSPNKLRIINIYIYPFAHWLAFCNSSVNPIIYGFFNENFRNGFQDAF--QICQKKAKPQEAYSLRAKRNIVINTSGLLVQEP--------------------------VSQNPGGENLGCGKSADNPTQESLIEEMGEATNSTVA-------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9Y5X5-1", "uniprot_id": "NPFF2_HUMAN", "id": "Q9Y5X5-1", "name": "Neuropeptide FF receptor 2", "aln": "---------------------------MNSFFGTPAASWCLLESDVSSAPDKEAGRERRALSVQQRGGPAWSGSLEWSRQSAGDRRRLGLSRQTAKSSWSRSRDRTCCCRRAWWILVPAADRARRERFIMNEKWDTNSSENWHPIWNVNDTKHHLYSDIN-ITYVN---------------------------------YYLHQPQVAAIFIISYFLIFFLCMMGNTVVCFIVMRNKHMHTVTNLFILNLAISDLLVGIFCMPITLLDNIIAGWPFGNTMCKISGLVQGISVAASVFTLVAIAVDRFQCVVYPFKPKLTIKTAFVIIMIIWVLAITIMSPSAVMLHVQEEKYYRVRLNSQNKTSPVYWCREDWPN-QEMRKIYTTVLFANIYLAPLSLIVIMYGRIGISLFRAAVPHTGRKNQEQWHVVSRKKQKIIKMLLIVALLFILSWLPLWTLMMLSDYADLSPNELQIINIYIYPFAHWLAFGNSSVNPIIYGFFNENFRRGFQEAFQLQLCQKRAKPMEAYALKAKSHVLINTSNQLVQES--------------------------TFQNPHGETLLYRKSAEKPQQELVMEELKETTNSSEI-------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A2AV71-1", "uniprot_id": "A2AV71_DANRE", "id": "A2AV71-1", "name": "Neuropeptide FF receptor 2", "aln": "---------------------------------------------------------------------------------------------------------------------------------MNESLDLNITLVDDGNWTFINGSSEFFLPLNNITYVG---------------------------------YYLHQPSVAAVFIVSYLLIFLVCMIGNGVVCFIVLRSKNMRTVTNLFILNLAISDLLVGIFCMPTTLLDNIITGWPFGSMVCKMSGMVQGISVSASVFTLVAIAVDRFRCIVYPFKQKLTISTATFIIVIIWVLAVSIMCPSGVMLQVTKEQNIRV-FRGNNRSSPFYWCRENWPN-QEMRKIYTTVLFANIYLAPLSLIVIMYARIGITLFKTAMPAGGKHGHDNRHSVSKKKQRVIKMLLIVALLFILSWLPLWTLMMLTDYVKLTEHQYRVINIYIYPFAHWLAFFNSSVNPIIYGFFNENFRRGFQAIFKFGLCPVGG-QHRTYSHRVQGNSVQPVNLQPSTEP--------------------------ISLN-SLENNSSRRMNHINEQDLVMEDLEKVSEYSMEGASL---------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q8IN35-1", "uniprot_id": "SIFAR_DROME", "id": "Q8IN35-1", "name": "Neuropeptide SIFamide receptor", "aln": "MMAASGRIRKRKHKSHTSGDVPSTTTSVPMPIPTMAPGKMVAETMEEAAALAGDYNNFTHNFVDLQNLLSFNELNGTSGSGGTAVSSLGSSSAIKLNNSAITDTLLGTVLTTATATVAPAASSLLATLAATTTASARGSLAGKSLAIADATSSTYYSNLLNLSPATTSLISAAAATKSYNDSALRWEQLDGSVDFGFDPLYRHSLAMSMVYCVAYIVVFLVGLIGNSFVIAVVLRAPRMRTVTNYFIVNLAIADILVIVFCLPATLIGNIFVPWMLGWLMCKFVPYIQGVSVAASVYSLIAVSLDRFIAIWWPLK-QMTKRRARIMIIGIWVIALVTTIPWLLFFDLVPAEEVFSDALVSAYSQPQFLCQEVWPPGTDGNLYFLLANLVACYLLPMSLITLCYVLIWIKVSTRSIPGESKDAQMDRMQQ-KSKVKVIKMLVAVVILFVLSWLPLYVIFARIKFGSDISQEEFEILKKVMPVAQWLGSSNSCINPILYSVN-KKYRRGFAAIIKSRSCCGRLRYYDNVAIASSTTSTRKSSHYHQNSSRKSPSSKGNAVSYIYEHNSLRRHNMMLKQDSNLSQQMLLKQDSHGSRQFLIKQESSCSDASGIRRPLCQQDSNGSKVSLSKQDSIVSYMEARRSAGHGLNDTLVDRDSVSMDVGRRQGATPSSLLDKRQKFVKQDSVISFVDQRPEQRRHQLVKQDSVISFADQRRGLLHKQDSLMANRTGDAPTHHVSILKKTDSQLSYGSSTSPRRNADLYE", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . . : . . : : :: * *. :: :: :*:::*.: ::** .* :*:* *:**** **.****:*:** :**:* **:.**:. * :* :**: :**:**:***::*:*:::*** .: :*:* ::* * . *: ** :*: * :::.: : :.. : *:* ** : . : . :. ** *:***.: * * .: : .:. : :.* ::****: *.:**:******:.:: .: . :: * : *.*:**. **.:***:*.. :::* ** : * . . . .. : . : :: :::: . :: : ", "identical_positions": 96, "similar_positions": 132, "identity": "12.61%" }, { "cls_id": "homologset.agr.MGI:1860137", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O88186-1", "uniprot_id": "GPIX_MOUSE", "id": "O88186-1", "name": "Platelet glycoprotein IX", "aln": "MTTWGLLFLLWPATTDTQACPRPCTCQSLETMGLKVNCEGQGLTALPVIPAHTRQLLLANNSLRSVPPGAFDHLPQLWDLDVTHNPWHCDCSLTYLRLWLEDHMPEALMHVYCASPDLATRRPLGQLTGYELGSCGWKLPPSWAYPGVWWDVSLVAVAVLGLILLAGLLNTFTESRN", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P14770-1", "uniprot_id": "GPIX_HUMAN", "id": "P14770-1", "name": "Platelet glycoprotein IX", "aln": "MPAWGALFLLWATAEATKDCPSPCTCRALETMGLWVDCRGHGLTALPALPARTRHLLLANNSLQSVPPGAFDHLPQLQTLDVTQNPWHCDCSLTYLRLWLEDRTPEALLQVRCASPSLAAHGPLGRLTGYQLGSCGWQLQASWVRPGVLWDVALVAVAALGLALLAGLLCATTEALD", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*.:** *****.:: *: ** ****::****** *:*.*:******.:**:**:********:************* ****:******************: ****::* ****.**:: ***:****:******:* .**. *** ***:*****.*** ****** : **: :", "identical_positions": 126, "similar_positions": 33, "identity": "71.19%" }, { "cls_id": "homologset.agr.MGI:1860138", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D4ABV1-1", "uniprot_id": "D4ABV1_RAT", "id": "D4ABV1-1", "name": "GTP-binding protein 2", "aln": "MDSRVSELFGGCCRPGGGPAMGGNLKARGAGGSSSCGGPKGKKKNG-RNRGGKANNPP-YLPPEAEDGNIEYKLKLVNPSQYRFEHLVTQMKWRLQEGRGEAVYQIGVEDNGLLVGLAEEEMRASLKTLHRMAEKVGADITVLREREVDYDSDMPRKITEVLVRKVPDNQQFLDLRVAVLGNVDSGKSTLLGVLTQGELDNGRGRARLNLFRHLHEIQSGRTSSISFEILGFNSKGEVVNYSDSRTAEEICESSSKMITFIDLAGHHKYLHTTIFGLTSYCPDCALLLVSANTGIAGTTREHLGLALALKVPFFIVVSKVDLCAKTTVERTVRQLERVLKQPGCHKVPMLVTSEDDAVTAAQQFAQSPNVTPIFTLSSVSGESLDLLKVFLNILPPLTNSKEQEELMQQLTEFQVDEIYTVPEVGTVVGGTLSSGICREGDQLVVGPTDDGCFLELRVCSIQRNRSACRVLRAGQAATLALGDFDRALLRKGMVMVSPEMNPTICSVFEAEIVLLFHATTFRRGFQVTVHVGNVRQTAVVEKIHAKDKLRTGEKAVVRFRFLKHPEYLKVGAKLLFREGVTKGIGHVTDVQAIAAGEAQASMGF----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q3UJK4-1", "uniprot_id": "GTPB2_MOUSE", "id": "Q3UJK4-1", "name": "GTP-binding protein 2", "aln": "MDSRVSELFGGCCRPGGGPAMGGNLKARGAGGSSSCGGPKGKKKNG-RNRGGKANNPP-YLPPEAEDGNIEYKLKLVNPSQYRFEHLVTQMKWRLQEGRGEAVYQIGVEDNGLLVGLAEEEMRASLKTLHRMAEKVGADITVLREREVDYDSDVPRKITEVLVRKVPDNQQFLDLRVAVLGNVDSGKSTLLGVLTQGELDNGRGRARLNLFRHLHEIQSGRTSSISFEILGFNSKGEVVNYSDSRTAEEICESSSKMITFIDLAGHHKYLHTTIFGLTSYCPDCALLLVSANTGIAGTTREHLGLALALKVPFFIVVSKVDLCAKTTVERTVRQLERVLKQPGCHKVPMLVTSEDDAVTAAQQFAQSPNVTPIFTLSSVSGESLDLLKVFLNILPPLTNSKEQEELMQQLTEFQVDEIYTVPEVGTVVGGTLSSGICREGDQLVVGPTDDGCFLELRVCSIQRNRSACRVLRAGQAATLALGDFDRALLRKGMVMVSPEMNPTICSVFEAEIVLLFHATTFRRGFQVTVHVGNVRQTAVVEKIHAKDKLRTGEKAVVRFRFLKHPEYLKVGAKLLFREGVTKGIGHVTDVQAITAGEAQATMGF----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9BX10-1", "uniprot_id": "GTPB2_HUMAN", "id": "Q9BX10-1", "name": "GTP-binding protein 2", "aln": "MDSRVSELFGGCCRPGGGPAVGGTLKARGAGSSSGCGGPKGKKKNG-RNRGGKANNPP-YLPPEAEDGNIEYKLKLVNPSQYRFEHLVTQMKWRLQEGRGEAVYQIGVEDNGLLVGLAEEEMRASLKTLHRMAEKVGADITVLREREVDYDSDMPRKITEVLVRKVPDNQQFLDLRVAVLGNVDSGKSTLLGVLTQGELDNGRGRARLNLFRHLHEIQSGRTSSISFEILGFNSKGEVVNYSDSRTAEEICESSSKMITFIDLAGHHKYLHTTIFGLTSYCPDCALLLVSANTGIAGTTREHLGLALALKVPFFIVVSKIDLCAKTTVERTVRQLERVLKQPGCHKVPMLVTSEDDAVTAAQQFAQSPNVTPIFTLSSVSGESLDLLKVFLNILPPLTNSKEQEELMQQLTEFQVDEIYTVPEVGTVVGGTLSSGICREGDQLVVGPTDDGCFLELRVCSIQRNRSACRVLRAGQAATLALGDFDRALLRKGMVMVSPEMNPTICSVFEAEIVLLFHATTFRRGFQVTVHVGNVRQTAVVEKIHAKDKLRTGEKAVVRFRFLKHPEYLKVGAKLLFREGVTKGIGHVTDVQAITAGEAQANMGF----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1PAI6-1", "uniprot_id": "A0A8M1PAI6_DANRE", "id": "A0A8M1PAI6-1", "name": "", "aln": "MDVQVANHCS--IKSAAKPSSPQKAAESGTETAPKKKSRTRRGKRGKRRRGKKANEPPPFLPPEAEEGNIEYKLKLVNPTQYRFEHLATQLKWRLQEGRGEAVYQIGVEDNGLLVGLTEEDMKASLKTLRRMAEKVGADITLLREREVDCDRAR-RKIAEVLVRKVPDDQQFLDLRVAVLGNVDSGKSTLLGVLTQGELDNGRGRARLNLFRHLHEIQTGRTSSISFEILGFNSKGEVVNYSDSRTAEEICESSSKMITFIDLAGHYKYLKTTIFGLTSYCPDFAMLVVGANTGIAGTTREHLGLAMALKVPIFIVVSKVDLCGKSTVEKTVRQLERVLKQPGCNKIPMVVANPDDAVTAAQQFAQSSSVTPIFTLSSVSGENLDLLKVFFNILPPLSNSKEQEELMQQLTEFQVDEIYSVPDVGTVVGGTLYSGVCREGDRLVVGPTDDGKFLRLKVCSIHRNRSGCRVLRAGQAATLALGNFDRSLLRKGMVMVSPKMNPTICWQFEAAIVLLFHAKTFRRGFQVTVHIGNVRQTATVECLLGKEELRTGERAVVCFRFLKHPEYLRVGAKLLFREGVTKGIGHVTHLLPSTQNHVPDQNHNQNHT", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "** :*:: . :... *: . *: :. . . : *.* *.** ***:** :******:************:*******.**:**************************:**:*:******:***********:******* * ***:*********:*************************************************:***********************************************:***:************ *:*:*.****************:*****:******:***.*:***:**************:*:**:*:. *************..*************.*******:******:*********************:**:********* **:*****:********* **.*:****:****.***************:***:***********:****** *** *******.***********:*******.** : .*::*****:*** **********:*******************.: . : ... ", "identical_positions": 475, "similar_positions": 80, "identity": "78.12%" }, { "cls_id": "homologset.agr.MGI:1860139", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9Z0U4-2", "uniprot_id": "GABR1_RAT", "id": "Q9Z0U4-2", "name": "Gamma-aminobutyric acid type B receptor subunit 1", "aln": "-MLLLLLVPLFLRPLGAGGAQTPNATSEGCQIIHPPWEGGIRYRGLTRDQVKAINFLPVDYEIEYVCRGEREVVGPKVRKCLANGSWTDMDTPSRCVRICSKSYLTLENGKVFLTGGDLPALDGARVEFRCDPDFHLVGSSRSVCSQ-GQWSTPKPHCQVNRTPHSERRAVYIGALFPMSG--GWPGGQACQPAVEMALEDVNSRRDILPDYELKLIHHDSKCDPGQATKYLYELLYNDPIKIILMPGCSSVSTLVAEAARMWNLIVLSYGSSSPALSNRQRFPTFFRTHPSATLHNPTRVKLFEKWGWKKIATIQQTTEVFTSTLDDLEERVKEAGIEITFRQSFFSDPAVPVKNLKRQDARIIVGLFYETEARKVFCEVYKERLFGKKYVWFLIGWYADNWFKT--YDPSINCTVEEMTEAVEGHITTEIVMLNPANTRSISNMTSQEFVEKLTKRLK-RHPEE-----TGGFQEAPLAYDAIWALALALNKTSGGGGRSGVRLEDFNYNNQTITDQIYRAMNSSSFEGVSGHVVFDASGSRMAWTLIEQLQGGSYKKIGYYDSTKDDLSWSKTDKWIGGSPPADQTLVIKTFRFLSQKLFISVSVLSSLGIVLAVVCLSFNIYNSHVRYIQNSQPNLNNLTAVGCSLALAAVFPLGLDGYHIGRSQFPFVCQARLWLLGLGFSLGYGSMFTKIWWVHTVFTKKEEKKEWRK-TLEPWKLYATVGLLVGMDVLTLAIWQIVDPLHRTIETFAKEEPKEDID-VSILPQLEHCSSKKMNTWLGIFYGYKGLLLLLGIFLAYETKSVSTEKINDHRAVGMAIYNVAVLCLITAPVTMILSSQQDAAFAFASLAIVFSSYITLVVLFVPKMRRLITRGEWQSETQDTMKTGSSTNNNEEEKSRLLEKENRELEKIIAEKEERVSELRHQLQSRQQLRSRRHP-----------PTPP-DPSGGLP--------------------RGPSEPPDRLSCDGSRVHLLYK---", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9WV18-1", "uniprot_id": "GABR1_MOUSE", "id": "Q9WV18-1", "name": "Gamma-aminobutyric acid type B receptor subunit 1", "aln": "-MLLLLLVPLFLRPLGAGGAQTPNVTSEGCQIIHPPWEGGIRYRGLTRDQVKAINFLPVDYEIEYVCRGEREVVGPKVRKCLANGSWTDMDTPSRCVRICSKSYLTLENGKVFLTGGDLPALDGARVDFRCDPDFHLVGSSRSICSQ-GQWSTPKPHCQVNRTPHSERRAVYIGALFPMSG--GWPGGQACQPAVEMALEDVNSRRDILPDYELKLIHHDSKCDPGQATKYLYELLYNDPIKIILMPGCSSVSTLVAEAARMWNLIVLSYGSSSPALSNRQRFPTFFRTHPSATLHNPTRVKLFEKWGWKKIATIQQTTEVFTSTLDDLEERVKEAGIEITFRQSFFSDPAVPVKNLKRQDARIIVGLFYETEARKVFCEVYKERLFGKKYVWFLIGWYADNWFKT--YDPSINCTVEEMTEAVEGHITTEIVMLNPANTRSISNMTSQEFVEKLTKRLK-RHPEE-----TGGFQEAPLAYDAIWALALALNKTSGGGGRSGVRLEDFNYNNQTITDQIYRAMNSSSFEGVSGHVVFDASGSRMAWTLIEQLQGGSYKKIGYYDSTKDDLSWSKTDKWIGGSPPADQTLVIKTFRFLSQKLFISVSVLSSLGIVLAVVCLSFNIYNSHVRYIQNSQPNLNNLTAVGCSLALAAVFPLGLDGYHIGRSQFPFVCQARLWLLGLGFSLGYGSMFTKIWWVHTVFTKKEEKKEWRK-TLEPWKLYATVGLLVGMDILTLAIWQIVDPLHRTIETFAKEEPKEDID-VSILPQLEHCSSKKMNTWLGIFYGYKGLLLLLGIFLAYETKSVSTEKINDHRAVGMAIYNVAVLCLITAPVTMILSSQQDAAFAFASLAIVFSSYITLVVLFVPKMRRLITRGEWQSEAQDTMKTGSSTNNNEEEKSRLLEKENRELEKIIAEKEERVSELRHQLQSRQQIRSRRHP-----------PTPP-DPSGGLP--------------------RGPSEPPDRLSCDGSRVHLLYK---", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9UBS5-1", "uniprot_id": "GABR1_HUMAN", "id": "Q9UBS5-1", "name": "Gamma-aminobutyric acid type B receptor subunit 1", "aln": "MLLLLLLAPLFLRPPGAGGAQTPNATSEGCQIIHPPWEGGIRYRGLTRDQVKAINFLPVDYEIEYVCRGEREVVGPKVRKCLANGSWTDMDTPSRCVRICSKSYLTLENGKVFLTGGDLPALDGARVDFRCDPDFHLVGSSRSICSQ-GQWSTPKPHCQVNRTPHSERRAVYIGALFPMSG--GWPGGQACQPAVEMALEDVNSRRDILPDYELKLIHHDSKCDPGQATKYLYELLYNDPIKIILMPGCSSVSTLVAEAARMWNLIVLSYGSSSPALSNRQRFPTFFRTHPSATLHNPTRVKLFEKWGWKKIATIQQTTEVFTSTLDDLEERVKEAGIEITFRQSFFSDPAVPVKNLKRQDARIIVGLFYETEARKVFCEVYKERLFGKKYVWFLIGWYADNWFKI--YDPSINCTVDEMTEAVEGHITTEIVMLNPANTRSISNMTSQEFVEKLTKRLK-RHPEE-----TGGFQEAPLAYDAIWALALALNKTSGGGGRSGVRLEDFNYNNQTITDQIYRAMNSSSFEGVSGHVVFDASGSRMAWTLIEQLQGGSYKKIGYYDSTKDDLSWSKTDKWIGGSPPADQTLVIKTFRFLSQKLFISVSVLSSLGIVLAVVCLSFNIYNSHVRYIQNSQPNLNNLTAVGCSLALAAVFPLGLDGYHIGRNQFPFVCQARLWLLGLGFSLGYGSMFTKIWWVHTVFTKKEEKKEWRK-TLEPWKLYATVGLLVGMDVLTLAIWQIVDPLHRTIETFAKEEPKEDID-VSILPQLEHCSSRKMNTWLGIFYGYKGLLLLLGIFLAYETKSVSTEKINDHRAVGMAIYNVAVLCLITAPVTMILSSQQDAAFAFASLAIVFSSYITLVVLFVPKMRRLITRGEWQSEAQDTMKTGSSTNNNEEEKSRLLEKENRELEKIIAEKEERVSELRHQLQSRQQLRSRRHP-----------PTPP-EPSGGLP--------------------RGPPEPPDRLSCDGSRVHLLYK---", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8N7UVF8-1", "uniprot_id": "A0A8N7UVF8_DANRE", "id": "A0A8N7UVF8-1", "name": "", "aln": "MEQLLFLVIFYLLP-TLVSSIHN-STTGGCAIIRPPRDGGIRYRGLTQEQIRSVQILPVDYEIEYICRGSRIIVGPKVRKCLPDGTWTDINQLSRCLMMCPRSWMSLENGRVSLQP-PGPPVEGTVLHYSCHAGFLLEGFNISHCTKLGKWDSPKPLCVYDSN-YTGKKKLYIGALFPMSG--GWPGGQACLPAAQMALDLVNNRSDILPDYELELIHYDSMCDPGEATKLLYDLLYTEPIKIVLMPGCSSVSTLVAEAARMWNLIVFSYGSSSPALSNRQRFPTFFRTHPSATLHNPTRVRLFQKWEWTKIATIQQTTEVFTSTLDDLEERVKEANIEISVRQSFLTDPAVAVKNLKRQDARIIVGLFYETEARKVFCEVFKEKLYGKKYVWFLIGWYADNWFKI--KDPAINCTVENMTEAVEGHITTEIVMLNPETVRGASNLTSQEFIAQLMSRLGGKNPEE-----TGGFQEAPLAYDAVWALALALNKTVAPLRAKGWGLEDFNYNNKEITAEIYRALNTSSFEGVSGHVVFDAQGSRMAWTLIEQLQGGSYKKIGYYDSTKGNLSWYGNDKWIGLSPPADQTKVIKEFRYLSQKLFVSVSVFAGLGILLGIVCLSFNIYNSSVRYIQNSQPYLNNMTAVGCVLALAAVFPLGIDGLHVRRSQFPVVCQFRLWLLGLGFSLAYGSMFTKIWWVHTVFTKKDEKKEKRK-HLEPWKLYATVAVLLAIDVLSLLIWQIMDPLHITVEQFTKEAPKEDLD-VLIQPLLEHCSSKKMNTWLGVVYGYKGLLLLLGIFLAYETKSISTEKINDHRAVGMAIYNVAVLCMITAPVTMILSSQQDASFAFASLAIIFSVYITLVVLFVPKIRRLITRGEWQSEQQDTLKTGSSTNNNDEEKSRQLERENRELQKIIQEKEERVTELRSQLAERQALRSRRRPSVQNQNQNHSVPSPQADPPSYCPTTDK---QSMPPSFSNSSNLYQGESKLSRNNCHNSRLPLLYK---", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8M2BHH0-1", "uniprot_id": "A0A8M2BHH0_DANRE", "id": "A0A8M2BHH0-1", "name": "", "aln": "--MALSLVLLFLLG-SFSLAMASRNITAGCAIIRPPRDGGIRYRGLTQEQIRSVQVLPVDYEIEYICRGSRVIVGPKVRKCLPDGTWTDLNQRSKCLLPCPRVWTSLENGRVTVHP-PGPAVEGTILHYSCLEGFILVGRNSTQCNKLGKWDSPKPVCHYDRH-YTGKKKLYIGALFPMSG--GWPGGQACLPAAQMALDLVNKRTDILPDYELELIHYDSMCDPGEATKLLYDLLYTEPIKIVLMPGCSSVSTLVAEAARMWNLIVLSYGSSSPALSNRQRFPTFFRTHPSATLHNPTRVQLFQKWKWTKIATIQQTTEVFTSTLDDLEQRVKEAGIEISVRQSFLTDPAVAVKNLKRQDARIIVGLFYETEARKVFCEVYKEKLYGKKYVWFLIGWYADNWFKI--KDPSINCTVEQMTEAVEGHVTTEIVMLNPETVRGASNLTSQEFLAQLMSKLGGKNPEE-----TGGFQEAPLAYDAVWALALALNKTVGPLKAKGRRLEDFNYNNKDITAEIYRALNTSSFEGVSGHVVFDAQGSRMAWTLIEQLQGGSYKKIGYYDMTKGNLSWYGNDRWIGSGPPADQTVVIQKFRYLSQKLFVSVSVFAGLGILMGIVCLTFNIYNSNVRYIQNSQPYLNNMTAVGCMMALAAVFPLGIDGLHVRNSQFPVVCQFRLWLLGLGFSLAYGSMFTKIWWVHTVFTKKDEKKDKRKQHLEPWKLYATVGVLLVIDILSLMIWQIVDPLHITVEKFTKEAPKGDVD-ELIEPLLQHCSSEKMNTWLGVVYGYKGLLLLLGIFLAYETKSVSTEKINDHRAVGMAIYNVSVLCMITAPVTMILSSKQDASFAFASLAIIFSVYITLVVLFVPKMRRLITRGEWQSDQQETMKTGSSTNNNDEEKSRQLERENKELQKIIQEKEERVSELRNQLSERQALRSRKRPTSNQNHSSPSIPTPQNDPKSLLPPPGYPLPSSDNHSFSNSSPLYQPDGKINRNNCHPGRLQLLYKCQH", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9V3Q9-1", "uniprot_id": "Q9V3Q9_DROME", "id": "Q9V3Q9-1", "name": "", "aln": "---------------MTSDGAVTFWIFLLCLIASPHLQGGVAGR--------------------------------------PD-------------------------------------------------------------------------------------ELHIGGIFPIAGKGGWQGGQACMPAARLALDDVNKQPNLLPGFKLILHSNDSECEPGLGASVMYNLLYNKPQKLMLLAGCSTVCTTVAEAAKMWNLIVLCYGASSPALSDRKRFPTLFRTHPSATVHNPTRIKLMKKFGWSRVAILQQAEEVFISTVEDLENRCMEAGVEIVTRQSFLSDPTDAVRNLRRQDARIIVGLFYVVAARRVLCEMYKQQLYGRAHVWFFIGWYEDNWYEVNLKAEGITCTVEQMRIAAEGHLTTEALMWNQNNQTTISGMTAEEFRHRLNQALIEEGYDINHDRYPEGYQEAPLAYDAVWSVALAFNKTMERLTTGKKSLRDFTYTDKEIADEIYAAMNSTQFLGVSGVVAFSSQGDRIALTQIEQMIDGKYEKLGYYDTQLDNLSWLNTEQWIGGKVPQDRTIVTHVLRTVSLPLFVCMCTISSCGIFVAFALIIFNIWNKHRRVIQSSHPVCNTIMLFGVIICLISVILLGIDGRFVSPEEYPKICQARAWLLSTGFTLAYGAMFSKVWRVHR-FTTKAKTDPKKK--VEPWKLYTMVSGLLSIDLVILLSWQIFDPLQRYLETFPLEDPVSTTDDIKIRPELEHCESQRNSMWLGLVYGFKGLILVFGLFLAYETRSIKVKQINDSRYVGMSIYNVVVLCLITAPVGMVIASQQDASFAFVALAVIFCCFLSMLLIFVPKVIEVIRHPKDKAES--KYNPDSAISKEDEERYQKLVTENEELQRLITQKEEKIRVLRQRLVERGDAKGTELNGATG--VASAAVATTSQPASLIN--------------------SSAHATPAATLAITQDTHEHRT---", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . * * * :**: * .: ::**.:**::* ** ***** **..:**: **.: ::**.::* * ** *:** .:. :*:***..* *::*:.***:*.* *****:******:.**:******:*:****:********:*****::*::*: *.::* :**: *** **::***:* **.:** ****::**: .*:**:************ . **:*:**::*::*:*: :***:**** ***:: .*.***::* *.***:*** :* * . *.:*::** :* . * . : . *:*********:*::***:*** *.**.*.:: *: :** *:*::.* **** *.*.:.*.*:* * ***: .*.*:*:**** .:*** .::*** * *:* * : :* :* **:.:..::. **.:... : ***:*. * **.*:* *.: .* :.* :*: **:** .: .::* :** * ***. **:*.**:**:*:* ** **.* :.. :* :******: *. *: :*:: * ***.***: :* *. * * * * * *:**.*.: . ***:.**:***:*::*:******:*:..::*** * ***:**** ***:***** *:::*:***:***.:**::*. :::::::****: .:* : : ::: . :..*: .:::**: : * **.**:::* :***:: ** :* .* :. . :. :* . . . ", "identical_positions": 358, "similar_positions": 259, "identity": "35.48%" }, { "cls_id": "homologset.agr.MGI:1860140", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O70552-1", "uniprot_id": "BTG4_MOUSE", "id": "O70552-1", "name": "Protein BTG4", "aln": "--------------------------------MRDEIATAVFFVTRLVKKHEKLSTQQIETFALKLMTILFEKYRGHWHPDCPSKGQAFRCIRINNNENKDPVLERACAESNVNFFHLGLPKEMTIWVDPYEVCCRYGEKKHPFTIASFKGRWENWELAQHVSCAVNRATGDCSSGTSSDEESCSREAQIIPKVNNPKSVYQVENFKQSLQPWFCLPRRKHLADGRGFLPGAACHPVPKSSKWCRPASRRVDRYHWVNAQLFSGQTAPGEPGEEALSSLKQK", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q4VFT8-1", "uniprot_id": "Q4VFT8_RAT", "id": "Q4VFT8-1", "name": "", "aln": "MGVVTVVRARLTAVRISLTHLEHCPYPDCFGIMRDEIATAVFFVTRLAKKHEKLSTQQIETFALKLMTVLFEKYRGHWHPDCPSKGQAFRCIRINNNENKDPVLERACSESNVNFFHLGLPKEMTIWVDPFEVCCRYGEKKHPFTIASFKGRWENWELAQSVSCAVNKATGDCSPSASSDEESCGREAQAIPKVNNPKSIYQVENFKPSFQPWLCLPRRKHLADGHGCLLGAAYHPMPKNSKWCRHAGHRVDRYHWVNTQLISGQTAPGELGEEALSSRKQK", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9NY30-1", "uniprot_id": "BTG4_HUMAN", "id": "Q9NY30-1", "name": "Protein BTG4", "aln": "--------------------------------MRDEIATTVFFVTRLVKKHDKLSKQQIEDFAEKLMTILFETYRSHWHSDCPSKGQAFRCIRINNNQNKDPILERACVESNVDFSHLGLPKEMTIWVDPFEVCCRYGEKNHPFTVASFKGRWEEWELYQQISYAVSRASSDVSSGTSCDEESCSKEPRVIPKVSNPKSIYQVENLKQPFQSWLQIPRKKNVVDGRVGLLGNTYHGSQKHPKCYRPAMHRLDRIL---------------------------", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *******:*******.***:***.**** ** ****:***.**.***.*****************:****:***** ****:* **************:*********:****:********:*** * :* **.:*:.* *..:*.*****.:*.: ****.****:*****:* .:*.*: :**:*::.**: * * : * * .* * * :*:** ", "identical_positions": 152, "similar_positions": 45, "identity": "53.9%" }, { "cls_id": "homologset.agr.MGI:1860188", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O60493-1", "uniprot_id": "SNX3_HUMAN", "id": "O60493-1", "name": "Sorting nexin-3", "aln": "-MAET---VADTRRLITK---PQNLNDAYGPPSNFLEIDVSNPQ-TVGVG---RGRFTTYEIRVKTNLPIFKLKESTVRRRYSDFEWLRSELERES------KVVVPPLPGKAFLRQLPFRGDDGIFDDNFIEERKQGLEQFINKVAGHPLAQN-ERCLHMFLQDEIIDKSYTPSKIRHA", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q5U211-1", "uniprot_id": "SNX3_RAT", "id": "Q5U211-1", "name": "Sorting nexin-3", "aln": "-MAET---VADTRRLITK---PQNLNDAYGPPSNFLEIDVSNPQ-TVGVG---RGRFTTYEIRVKTNLPIFKLKESTVRRRYSDFEWLRSELERES------KVVVPPLPGKAFLRQLPFRGDDGIFDDNFIEERKQGLEQFINKVAGHPLAQN-ERCLHMFLQDEIIDKSYTPSKIRHA", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O70492-1", "uniprot_id": "SNX3_MOUSE", "id": "O70492-1", "name": "Sorting nexin-3", "aln": "-MAET---VADTRRLITK---PQNLNDAYGPPSNFLEIDVSNPQ-TVGVG---RGRFTTYEIRVKTNLPIFKLKESTVRRRYSDFEWLRSELERES------KVVVPPLPGKAFLRQLPFRGDDGIFDDNFIEERKQGLEQFINKVAGHPLAQN-ERCLHMFLQDEIIDKSYTPSKIRHA", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9VG51-1", "uniprot_id": "Q9VG51_DROME", "id": "Q9VG51-1", "name": "Sorting nexin-3", "aln": "MMVESDGTADATRRLNVK---KQTLDDAYAVPANFLEIDVVNPLTTMAAG---KKRYTDYEVRMRTNLPVFKVKESSVRRRYSDFEWLRNELERDS------KIVVPPLPGKAWKRQMPFRGDEGIFDESFIEERRKGLEAFINKIAGHPLAQN-ERCLHMFLQENVIDKNYVPGKIRNT", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q08826-1", "uniprot_id": "SNX3_YEAST", "id": "Q08826-1", "name": "Sorting nexin-3", "aln": "MPREFKSFGSTEKSLLSKGHGEPSYSEIYAEPENFLEIEVHNPKTHIPNGMDSKGMFTDYEIICRTNLPSFHKRVSKVRRRYSDFEFFRKCLIKEISMLNHPKVMVPHLPGKILLSNR--------FSNEVIEERRQGLNTWMQSVAGHPLLQSGSKVLVRFIEAEKFVG----------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * : * * . .: *. * *****:* ** : * : :* **: :**** *: : *.*********::*. * :: *::** **** : *.:..****::**: :::.:***** *. .: * *:: : : ", "identical_positions": 56, "similar_positions": 41, "identity": "31.11%" }, { "cls_id": "homologset.agr.MGI:1860191", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "F7F6Z7-1", "uniprot_id": "F7F6Z7_RAT", "id": "F7F6Z7-1", "name": "DNA-directed DNA/RNA polymerase mu", "aln": "MLPKRRRRVRAGSPHSALASSTPP-AARFPGVAIYLAEPRMGRSRR--------AFLTR---------LARSKGFRILDVYSSEVTHVVMEETSAKEAICWQKD-MNALLPDCPQPALLDISWFTESMAAGQPVPE-EVRHRLEVAEPRKEPPISVTIPAYACQRPSPLT---------------PHNTLLSEALETLAEAAGFEGKEGRFLTFYRAASMLKSLPYPVTSLSQLHG-LPYFGEHSFRVIQELLEHGTCEEVEQIRCSERHQTMKLFTHIFGVGVKTASRWYQEGLRTLDELREQ-PQRLTQQQKAVLPTGLQYYQDLSTPVSRAEAEALQQLVEAAMREILPGATVTLTGGFRRGKLQGHDVDFLITHPEE-------------------------------GQEVGLLPRVMRCLQSQGLVLYHQYHRSHLADSAHILRQRS-TMDAFERSFCILR-----LPQSQQAALEGPLHPCPTWKAV---------RVDLVVTPNSQFPFALLGWTGSQFFERELRRFSRQEKGLCLNSHGLFDPERKTFFHATSEEDVFRFLGLKYLPPEQRNA-------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9JIW4-1", "uniprot_id": "DPOLM_MOUSE", "id": "Q9JIW4-1", "name": "DNA-directed DNA/RNA polymerase mu", "aln": "MLPKRRR-VRAGSPHSAVASSTPPSVVRFPDVAIYLAEPRMGRSRR--------AFLTR---------LARSKGFRVLDAYSSKVTHVVMEGTSAKEAICWQKN-MDALPTGCPQPALLDISWFTESMAAGQPVPE-EGRHHLEVAEPRKEPPVSASMPAYACQRPSPLT---------------HHNTLLSEALETLAEAAGFEANEGRLLSFSRAASVLKSLPCPVASLSQLHG-LPYFGEHSTRVIQELLEHGTCEEVKQVRCSERYQTMKLFTQVFGVGVKTANRWYQEGLRTLDELREQ-PQRLTQQQK----AGLQYYQDLSTPVRRADAEALQQLIEAAVRQTLPGATVTLTGGFRRGKLQGHDVDFLITHPEE-------------------------------GQEVGLLPKVMSCLQSQGLVLYHQYHRSHLADSAHNLRQRSSTMDAFERSFCILG-----LPQPQQAALAGALPPCPTWKAV---------RVDLVVTPSSQFPFALLGWTGSQFFERELRRFSRQEKGLWLNSHGLFDPEQKRVFHATSEEDVFRLLGLKYLPPEQRNA-------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9NP87-1", "uniprot_id": "DPOLM_HUMAN", "id": "Q9NP87-1", "name": "DNA-directed DNA/RNA polymerase mu", "aln": "MLPKRRR-ARVGSPSGDAASSTPP-STRFPGVAIYLVEPRMGRSRR--------AFLTG---------LARSKGFRVLDACSSEATHVVMEETSAEEAVSWQERRMAAAPPGCTPPALLDISWLTESLGAGQPVPV-ECRHRLEVAGPRKGPLSPAWMPAYACQRPTPLT---------------HHNTGLSEALEILAEAAGFEGSEGRLLTFCRAASVLKALPSPVTTLSQLQG-LPHFGEHSSRVVQELLEHGVCEEVERVRRSERYQTMKLFTQIFGVGVKTADRWYREGLRTLDDLREQ-PQKLTQQQK----AGLQHHQDLSTPVLRSDVDALQQVVEEAVGQALPGATVTLTGGFRRGKLQGHDVDFLITHPKE-------------------------------GQEAGLLPRVMCRLQDQGLILYHQHQHS-CCESPTRLAQQS-HMDAFERSFCIFR-----LPQPPGAAVGGSTRPCPSWKAV---------RVDLVVAPVSQFPFALLGWTGSKLFQRELRRFSRKEKGLWLNSHGLFDPEQKTFFQAASEEDIFRHLGLEYLPPEQRNA-------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P25615-1", "uniprot_id": "DPO4_YEAST", "id": "P25615-1", "name": "DNA polymerase IV", "aln": "MSLKGKFFAFLPNPNTSSNKFFKSILEKKGATIVSSIQNCLQSSRKEVVILIEDSFVDSDMHLTQKDIFQREAGLNDVDEFLGKIEQSGIQCVKTSCITKWVQNDKFAFQKDDLIKFQPSIIVISDNADDGQSSTDKESEISTDVESERNDDSNNKDMIQASKPLKRLLQGDKGRASLVTDKTKYKNNELIIGALKRLTKKYEIEGEKFRARSYRLAKQSMENCDFNVRSGEEAHTKLRNIGPSIAKKIQVILDTGVLPGLNDSVG--LEDKLKYFKNCYGIGSEIAKRWNLLNFESFCVAAKKDPEEFVSDWT--ILFGWSYYDDWLCKMSRNECFTHLKKVQKALRGIDPECQVELQGSYNRGYSKCGDIDLLFFKPFCNDTTELAKIMETLCIKLYKDGYIHCFLQLTPNLEKLFLKRIVERFRTAKIVGYGERKRWYSSEIIKKFFMGVKLSPRELEELKEMKNDEGTLLIEEEEEEETKLKPIDQYMSLNAKDGNYCRRLDFFCCKWDELGAGRIHYTGSKEYNRWIR-ILAAQKGFKLTQHGLFR--NNILLESFNERRIFELLNLKYAEPEHRNIEWEKKTA", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* * : . .* . . : . : : : **: :*: : *. *:. :* .: : :: ..:. * : * . .* :::. **. . * . :* *: : : * :* : **: *:: :*..: * :: * . :: * : .: : * :* : :* :*: *. :: :.:* *.: :*:* : *.** .:.:: :: *:.:..: . * .:::* : * : : : :: *: * . * * *.:.** : *:*:*: :* . * :* ::: :: :: * : :: .: : ..: : * * : :: *:*:. .:: . : :***: ::* :* : :**: *..**** .: .:.: .*. :*. *.*:* **:** ", "identical_positions": 81, "similar_positions": 163, "identity": "13.75%" }, { "cls_id": "homologset.agr.MGI:1860197", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9ERH3-1", "uniprot_id": "WDR7_RAT", "id": "Q9ERH3-1", "name": "WD repeat-containing protein 7", "aln": "MAGNSLVLPIVLWGRKAPTHCISSILLTDDGGTIVTGCHDGQICLWDLS-EELEVNPRALLFGHTAAITCLSKACASGDKQYTVSASANGEMCLWDVNDGRCIEFTKLACTHTGIQFYQFSVGNQREGRLLCHGHYPEILVVDATSLEVLYSLVSKISPDWISSMSIIRSHRTQEDTVVALSVTGILKVWIVTSEISGLQDTEPIFEEESKPIYCQNCQSLSFCAFTQRSLLVVCSKYWRVFDAGDYSLLCSGPSEDGQTWTGGDFVSADKVIIWTENGQSYIYKLPASCLPASDSFRSDVGKAVENLIPPVQHSLLDQKDRELVICPPVTRFFYGCKEYLHKLLIQGDSSGRLSIWNIADI--------ADKQEANEGLKTTTCISLQDAFDKLKPCPAGIIDQLSVIPNSNEPLKVTASVYIPAHGRLVCGREDGSIIIVPATQTAIVQLLQGEHMLRRGWPPHRTLRGHRNKVTCLLYPHQVSARYDQRYLISGGVDFSVIIWDIFSGEMKHIFCVHGGEITQLLVPPENCSARVQHCVCSVASDHSVGLLSLREKKCIMLASRHLFPIQVIKWRPSDDYLVVGCTDGSVCVWQMDTGALDRCAMGITAVEILNACDEAVP--------------AAVDSLSHPAVNLKQAMTRRSLAALKNMAHHKLQTLATNLLASEASDKGNLPKYSHNSLMVQAIKTNLTDPDIHVLFFDVEALIIQLLTEEASRPNTALISPENLQKASGSSDKGGSFLTGKRAAVLFQQVK-------ETIKENIKEHLLDEEEDEEEVMR----------QRREESDPEYRASKSKPLTLLEYNLTMDTAKLFMSCLHAWGLNEVLDEVCLDRLGMLKPHCTVSFGLLSRGGHMSLMLPGYN-QAAGKLLQAKAEAGRKGPATESVG-----------KGTYTVSRAVTTQHLLSIISLANTLMSMTNATFIGDHMKKGPTRPPRPGTPDLSKARDSPPASSNIVQGQIKQAAAP-VSARSAADHSGSAS-ASPALRTCFLVNEGWSQLAAMHCVMLPD---LLGLGKFRPPLLEMLARRWQDRCLEVREAAQALLLAELRRIEQAGRKETIDTWAPYLPQYMDHVISPGVTAEAMQTMAAAPDASGPEAKVQEEEHDLVDDDITTGCLS----SVP----------------QMKKMSTSYEERRKQATAIVLLGVIGAEFGAEIEPPKLLTRPRSSSQIPEGFGLTSGGSN---------------YSLARHTCKALTFLLLQPPSPKLPPHSTIRRTAIDLIGRGFTVWEPYMDVSAVLMGLLELCADAEKQLANITMGLPLSPAADSARSARHALSLIATARPPAFITTIAKEVHRHTALAANTQSQQS-IHTTTLARAKGEILRVIEILIEKMPTDVVDLLVEVMDIIMYCLEGSLVKKKGLQECFPAICRFYMVSYYERSHRIAVGARHGSVALYDIRTGKCQTIHGHKGPITAVSFAPDGRYLATYSNTDSHISFWQMNTSLLGSIGMLNSAPQLRCIKTYQVPPVQPASPGSHNALRLARLIWTSNRNVILMAHDGKEHRFMV", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q920I9-1", "uniprot_id": "WDR7_MOUSE", "id": "Q920I9-1", "name": "WD repeat-containing protein 7", "aln": "MAGNSLVLPIVLWGRKAPTHCISSILLTDDGGTIVTGCHDGQICLWDVS-VELEVNPRALLFGHTASITCLSKACASGDKRYTVSASANGEMCLWDVNDGRCIEFTKLACTHTGIQFYQFSVGNQQEGRLLCHGHYPEILVVDATSLEVLYSLVSKISPDWISSMSIIRSQRTQEDTVVALSVTGILKVWIVTSEMSGMQDTEPIFEEESKPIYCQNCQSISFCAFTQRSLLVVCSKYWRVFDAGDYSLLCSGPSENGQTWTGGDFVSADKVIIWTENGQSYIYKLPASCLPASDSFRSDVGKAVENLIPPVQHSLLDQKDKELVICPPVTRFFYGCKEYLHKLLIQGDSSGRLNIWNIADI--------AEKQEADEGLKMTTCISLQEAFDKLKPCPAGIIDQLSVIPNSNEPLKVTASVYIPAHGRLVCGREDGSIIIVPATQTAIVQLLQGEHMLRRGWPPHRTLRGHRNKVTCLLYPHQVSARYDQRYLISGGVDFSVIIWDIFSGEMKHIFCVHGGEITQLLVPPENCSARVQHCICSVASDHSVGLLSLREKKCIMLASRHLFPIQVIKWRPSDDYLVVGCTDGSVYVWQMDTGALDRCAMGITAVEILNACDEAVP--------------AAVDSLSHPAVNLKQAMTRRSLAALKNMAHHKLQTLATNLLASEASDKGNLPKYSHNSLMVQAIKTNLTDPDIHVLFFDVEALIIQLLTEEASRPNTALISPENLQKASGSSDKGGSFLTGKRAAVLFQQVK-------ETIKENIKEHLLDEEEDEEEARR----------QSREDSDPEYRASKSKPLTLLEYNLTMDTAKLFMSCLHAWGLNEVLDEVCLDRLGMLKPHCTVSFGLLSRGGHMSLMLPGYN-QAAGKLLHAKAEVGRKLPAAEGVG-----------KGTYTVSRAVTTQHLLSIISLANTLMSMTNATFIGDHMKKGPTRPPRPGTPDLSKARDSPPPSSNIVQGQIKQAAAPVVSARSDADHSGSDS-ASPALPTCFLVNEGWSQLAAMHCVMLPD---LLGLERFRPPLLEMLARRWQDRCLEVREAAQALLLAELRRIEQAGRKETIDTWAPYLPQYMDHVISPGVTAEAMQTMAAAPDASGPEAKVQEEEHDLVDDDITAGCLS----SVP----------------QMKKISTSYEERRKQATAIVLLGVIGAEFGAEIEPPKLLTRPRSSSQIPEGFGLTSGGSN---------------YSLARHTCKALTYLLLQPPSPKLPPHSTIRRTATDLIGRGFTVWEPYMDVSAVLMGLLELCADAEKQLANITMGLPLSPAADSARSARHALSLIATARPPAFITTIAKEVHRHTALAANTQSQQS-IHTTTLARAKGEILRVIEILIEKMPTDVVDLLVEVMDIIMYCLEGSLVKKKGLQECFPAICRFYMVSYYERSHRIAVGARHGSVALYDIRTGKCQTIHGHKGPITAVSFAPDGRYLATYSNTDSHISFWQMNTSLLGSIGMLNSAPQLRCIKTYQVPPVQPASPGSHNALKLARLIWTSNRNVILMAHDGKEHRFMV", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9Y4E6-1", "uniprot_id": "WDR7_HUMAN", "id": "Q9Y4E6-1", "name": "WD repeat-containing protein 7", "aln": "MAGNSLVLPIVLWGRKAPTHCISAVLLTDDGATIVTGCHDGQICLWDLS-VELQINPRALLFGHTASITCLSKACASSDKQYIVSASESGEMCLWDVSDGRCIEFTKLACTHTGIQFYQFSVGNQREGRLLCHGHYPEILVVDATSLEVLYSLVSKISPDWISSMSIIRSHRTQEDTVVALSVTGILKVWIVTSEISDMQDTEPIFEEESKPIYCQNCQSISFCAFTQRSLLVVCSKYWRVFDAGDYSLLCSGPSENGQTWTGGDFVSSDKVIIWTENGQSYIYKLPASCLPASDSFRSDVGKAVENLIPPVQHILLDRKDKELLICPPVTRFFYGCREYFHKLLIQGDSSGRLNIWNISDT--------ADKQGSEEGLAMTTSISLQEAFDKLNPCPAGIIDQLSVIPNSNEPLKVTASVYIPAHGRLVCGREDGSIVIVPATQTAIVQLLQGEHMLRRGWPPHRTLRGHRNKVTCLLYPHQVSARYDQRYLISGGVDFSVIIWDIFSGEMKHIFCVHGGEITQLLVPPENCSARVQHCICSVASDHSVGLLSLREKKCIMLASRHLFPIQVIKWRPSDDYLVVGCSDGSVYVWQMDTGALDRCVMGITAVEILNACDEAVP--------------AAVDSLSHPAVNLKQAMTRRSLAALKNMAHHKLQTLATNLLASEASDKGNLPKYSHNSLMVQAIKTNLTDPDIHVLFFDVEALIIQLLTEEASRPNTALISPENLQKASGSSDKGGSFLTGKRAAVLFQQVK-------ETIKENIKEHLLDDEEEDEEIMR----------QRREESDPEYRSSKSKPLTLLEYNLTMDTAKLFMSCLHAWGLNEVLDEVCLDRLGMLKPHCTVSFGLLSRGGHMSLMLPGYN-QPACKLSHGKTEVGRKLPASEGVG-----------KGTYGVSRAVTTQHLLSIISLANTLMSMTNATFIGDHMKKGPTRPPRPSTPDLSKARGSPPTSSNIVQGQIKQVAAPVVSARSDADHSGSDPPSAPALHTCFLVNEGWSQLAAMHCVMLPD---LLGLDKFRPPLLEMLARRWQDRCLEVREAAQALLLAELRRIEQAGRKEAIDAWAPYLPQYIDHVISPGVTSEAAQTITTAPDASGPEAKVQEEEHDLVDDDITTGCLS----SVP----------------QMKKISTSYEERRKQATAIVLLGVIGAEFGAEIEPPKLLTRPRSSSQIPEGFGLTSGGSN---------------YSLARHTCKALTFLLLQPPSPKLPPHSTIRRTAIDLIGRGFTVWEPYMDVSAVLMGLLELCADAEKQLANITMGLPLSPAADSARSARHALSLIATARPPAFITTIAKEVHRHTALAANTQSQQN-MHTTTLARAKGEILRVIEILIEKMPTDVVDLLVEVMDIIMYCLEGSLVKKKGLQECFPAICRFYMVSYYERNHRIAVGARHGSVALYDIRTGKCQTIHGHKGPITAVAFAPDGRYLATYSNTDSHISFWQMNTSLLGSIGMLNSAPQLRCIKTYQVPPVQPASPGSHNALKLARLIWTSNRNVILMAHDGKEHRFMV", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9W543-1", "uniprot_id": "Q9W543_DROME", "id": "Q9W543-1", "name": "", "aln": "MVSTNLVVPVVLWGPTAPTHCISSVFLSDDQFTLVTGCYDGQICLWQVEPTTLKMSPRCLLVGHSAPVLCLVRASLLPENNFLVSSSENGEMCTWDLTDGKCMEAVKLPQVHTQIQSYHT--ANSEDVRLFCIGYYAEIMVMDPFSLEVIYVLSSKVKPDWISAIHVLRPMRRKDDVVLAITTTGTVKVWTLTGNEN--KHAEPIYENESKEIRCLNAITMNCCAQNQRTVLLVCTKYWQIYDAGDFTVLCSVIAPARERWQGGDFITSDRVMLWTDEGKGYLYKLPANCIPDNKEFHS---KSVVRDAPYLYYVLQHAGDK-VLSCPPAMKLLQGAGG--QHNLLRGDSEGYISVWNVPEVPLDNISILQAKQMPPRPLKPHVCTSLVEAWSIMDPPPVGILDQLSRITES--PVKLTSSIYLPQQSRLVIGREDGSIVIVPATQTVMMQLLVGIKQNFSDWPSHQILYGHRGRVNCLLCPSMIHSRYEKSHLLSGGIDFAVCLWDLYSGSLLHRFCVHAGEITQLLVPPESCSPRILKCICSVASDHSVTLVSLQERKCVTLASRHLFPVVTIKWRPLDDFLIVGCSDGSVYVWQMETGHLDRVLHGMLAEEVLSACDEQAEDGGSGGGGGSNGASASEMGMANPAVHFFRGLKSRNMNAIRHATQRGITQLQQ-LQGHNQGNFDFLMKHRSNPLVIQGLRTNPKDAESHILFFDIEGLIFELHSEEYAQMTPATLESLGVHLQNPKDGKSMHLDASKKIGDFFNKVKNKAVDVEKILKDKDKHGLVQKFKEKTEIVEKKVQAKVESLQKAVEPHEEQQDLKSKIASKMEVTHVMEVAQLLLSLLHSWGLDPHLDKMCETRLGLLRPIVPISYGVLSKAGYMSLLLPTWQNNYAIPPGIQLPSSSKKRPLPEELQRLEHLTAVFTSRLHWELSTTLTTNHILALVAMSNTLLSMSAASFLPDSEKHKKLQR---------------------------------LAQRTDSTLSNEEEREELMAHHISQIKHAWSLLATHHCFLLPDKIEALEPKKFKRPQVEMMVKRWQHHCIEIREAAQQILLGELTRMGKKGRKQLVESWAQYLPLYTHTEPIVGAQQQLALISQPASGGAGSGSGGNGGVGVGVSGGGGAGSGSGPGGSVPGGDAHQDEDYEEEEEEIIRKPSSLSELKRKQTTAVILLGVIGAEFGQDIS--QESPNHRGSISMATGANLTSGVAGGERRKSSVVEGFGIANNLARLTSMALAHLLYAPPSPKLPQYTPLRRAAIDLLGRGFTVWEPYLDVSKVLLGLLEISCEG-KAVPNLNYKLPLTPQADACRTARHALRLIATARPAAFITTMAREVARYNTMQQNAQSINTPLTQSVLHKAKGEILQCVEMLIDKMQSEIAGLLVEVMDIALHCVDGNELKNRGLAELCPAICKFNQISHCAQTRRIAVGANSGNLAIYELRQNKCQMIPAHTHPITSLAFSPDGKYLVSYSCAENRLSFWQTSTGMFG-----LGQSQTRCTKGYSTAPIPDVS--RLNPMRLAKLVWINNRTVTLMLADGSETRFNV", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*....**:*:**** .*******:::*:** *:****:*******::. *::.**.**.**:*.: ** :*. ::.: **:* .**** **:.**:*:* .**. .** ** *: .*..: **:* *:*.**:*:*. ****:* * **:.*****:: ::*. * ::*.*:*::.** :*** :*.: . :.:***:*:*** * * *. ::. ** .**::*:**:***:::****:::*** : : * ****:::*:*::**::*:.*:*****.*:* ...*:* *:* . * : : * . *: :: ***. ::: *. :: *::***.* :.:**:.: ** . . * .. ** :*:. :.* *.**:**** *.:* *:*:*:*:*:* :.*** *******:*******.::*** * : .**.*: * ***.:*.*** * : :**:: :*:***:**:* :**::**.: * ****.***********.**.*: :*:********* *:**:*:**: ********: .***** **:*:***:**** ****:** *** *: * *:*.**** . *: .:::***:: :.:. *.: *::: ::: : * * . : .: . * *: *.*::*.::** .*.: *:****:*.**::* :** :: ..* :.. .:: . ...*. : :.*: . :*::** : :*:: *. *::. ::. * . * :.. * : *** : :* . .*:.*:*::* **:***: **::* ***:*:* .:*:*:**:.*:***:** :: : * .. .:* * .* : : : :* ::**:*:*::::::***:**: *:*: * *: : :: *: : *.. ::..** **: **.:*** * :*: * :**:.:***.:*:*:***** :**.** *: : ***: :::** *** * . *. : .*...:*. : : *... :*. * *** ::* *: * :***:**::********** :*. : .. *.* .:. * .**** :. .*** *. **:.** ******* ::.:**:* **:**********:*** **:****:..:. * :.*:. ***:* **:.*:***** *******.*****:*:** *:.:: *:** :. : :.* :******: :*:**:** :::..******** ::*::*. :*::** * ****:* :*: :.:******. *.:*:*::* .*** * .*. ***:::*:***:**.:** ::.::**** .*.::* . .* ** * *...*: .* *.::**:*:* .**.* ** **.* ** *", "identical_positions": 623, "similar_positions": 496, "identity": "39.41%" }, { "cls_id": "homologset.agr.MGI:1860203", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O14625-1", "uniprot_id": "CXL11_HUMAN", "id": "O14625-1", "name": "C-X-C motif chemokine 11", "aln": "MSVKGMAIALAVILCATVVQGFPMFKRGRCLCIGPGVKAVKVADIEKASIMYPSNNCDKIEVIITLKENKGQRCLNPKSKQAR-LIIKKVERKNF---------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9JHH5-1", "uniprot_id": "CXL11_MOUSE", "id": "Q9JHH5-1", "name": "C-X-C motif chemokine 11", "aln": "MNRKVTAIALAAIIWATAAQGFLMFKQGRCLCIGPGMKAVKMAEIEKASVIYPSNGCDKVEVIVTMKAHKRQRCLDPRSKQAR-LIMQAIEKKNFLRRQNM---------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A0R4INB9-1", "uniprot_id": "CX111_DANRE", "id": "A0A0R4INB9-1", "name": "C-X-C motif chemokine 11-1", "aln": "-MKTVTALLLVS-LAVVAIEGQHMKS-QRCVCLGAGLNMVKPVLIEKIEILPSSPSCGHMEVIATLKNGAGKRCLNPKSKFTKKIIDK-IEKNNRNAR------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "B0R191-1", "uniprot_id": "CX116_DANRE", "id": "B0R191-1", "name": "C-X-C motif chemokine 11-6", "aln": "-MKTLAAFLLLSCLIAGEVNGQDRSSRARCFCVDKGLNMVLLKNLDKVEIFPPSPSCNKHEIVVTLKNGAGQKCLNPDSKFTKNVVLKAIGKRMQQSVPHSTTTGTVKSSMTSSTSAPTAFK", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . *: * : . :* . **.*:. *:: * ::* .:: .* .*.: *:: *:* ::**:* ** :: :: : : :. ", "identical_positions": 19, "similar_positions": 34, "identity": "15.57%" }, { "cls_id": "homologset.agr.MGI:1860206", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9JHT5-1", "uniprot_id": "AMMR1_MOUSE", "id": "Q9JHT5-1", "name": "Nuclear protein AMMECR1", "aln": "MAAGCCGVKKQKLSSSPPSGSGGGGGASSSSHCSGESQCRAGELGLGGAGTRLNGLGGLSGGGGSGGGGGCPLSPPQGCGGGGGGGGGGGSGSGGGGISLSPPLSCGVGTLLSTPAAATASSPSSS----SSSPGSRKMVVSAEMCCFCFDVLYCHLYGYQQPRTPRFTNEPYPLFVTWKIGRDKR-----------LRGCIGTFSAMNLHSGLREYTLTSALKDSRFPPMTRDELPRLFCSVSLLTNFEDVC--------DYLDWEVGVHGIRIEFIN-EKGSKRTATYLPEVAKEQGWDHIQTIDSLLRKGGYKAPITNEFR----KTIKLTRYRSEKMTLSYAEYLAHRQHHHFQNGIGHPLPPYNHYS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D3ZBY1-1", "uniprot_id": "D3ZBY1_RAT", "id": "D3ZBY1-1", "name": "", "aln": "MAAGCCGVKKQKLSSSPPSGSGGGGGASSSSHCSGESQCRAGELGLGGAGTRLNGLGGLSGGGGSGGGGGCTLSPPQGCGGGGGGGG----------ISLSPPLSCGVGTLLSTPAAATASSPSSS----SSSPGSRKMVVSAEMCCFCFDVLYCHLYGYQQPRTPRFTNEPYPLFVTWKIGRDKR-----------LRGCIGTFSAMNLHSGLREYTLTSALKDSRFPPMTRDELPRLFCSVSLLTNFEDVC--------DYLDWEVGVHGIRIEFIN-EKGSKRTATYLPEVAKEQGWDHIQTIDSLLRKGGYKAPITNEFR----KTIKLTRYRSEKMTLSYAEYLAHRQHHHFQNGIGHPLPPYNHYS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9Y4X0-1", "uniprot_id": "AMMR1_HUMAN", "id": "Q9Y4X0-1", "name": "Nuclear protein AMMECR1", "aln": "MAAGCCGVKKQKLSSSPPSGSGGGGGASSSSHCSGESQCRAGELGLGGAGTRLNGLGGLTGGGS---GSGCTLSPPQGCGGGG--GG----------IALSPPPSCGVGTLLSTPAAATSSSPSSSSAASSSSPGSRKMVVSAEMCCFCFDVLYCHLYGYQQPRTPRFTNEPYPLFVTWKIGRDKR-----------LRGCIGTFSAMNLHSGLREYTLTSALKDSRFPPMTRDELPRLFCSVSLLTNFEDVC--------DYLDWEVGVHGIRIEFIN-EKGSKRTATYLPEVAKEQGWDHIQTIDSLLRKGGYKAPITNEFR----KTIKLTRYRSEKMTLSYAEYLAHRQHHHFQNGIGHPLPPYNHYS", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VCF0-1", "uniprot_id": "Y5902_DROME", "id": "Q9VCF0-1", "name": "Uncharacterized protein CG5902", "aln": "MSNSHYNNYQQQQPHSS----------------NGDPEYQHQQM----------------------------VHQPQ-------------------------RFSNGHG---------------------------MKTVAVPDMCLFCFEVLDCELNNVDGPSVPVFSNDAYPLFVTWKIGRDKR-----------LRGCIGTFSAMELHHGLREYALTSAFKDSRFAPISRDELPRLTVSVSILQNFEEAQ--------GHLDWQLGVHGIRIEFLT-ERGCKRTATYLPQVATEQGWDQLQTIDSLLRKGGYRAAITPETR----KSIKLTRYRSQEIQMHYKEYREYQERRAQFGKVQC---------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q12012-1", "uniprot_id": "YO289_YEAST", "id": "Q12012-1", "name": "Uncharacterized protein YOR289W", "aln": "MALRLFRKSSFFAKISMEGPKGS----------SPFAFYAFY--------------------------------------------------------------------------------------------QLYSHLNPGKSSSLSLEDIRRRLY----PDFKIDYNEKTSLFITWKKKSNKHHTIDTNEENYILRGCIGTFAKMPIAHGIEKYSLIAALEDRRFSPIQKRELVDLKCSCNILGNFKTIFRGGGNPNGDIFDWELGKHGIELYFKHPKTGTTCSATFLPDVMPEQHWNKEDTFANLIEKAGYWGNISEVMDNFETYFIEVIRYEGKKSSITYEEFNKQLKDIEA---------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*: . * . . . : . . :.:: : .* * *: .**:*** :*: ********: * : *:.:*:* :*::* **.*: : ** * * .:* **: . :**::* ***.: * : * . :**:**:* ** *:: :*: .*:.*.** . *: *:: **..:: : * *: : ", "identical_positions": 62, "similar_positions": 64, "identity": "16.67%" }, { "cls_id": "homologset.agr.MGI:1860236", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O35550-1", "uniprot_id": "RABE1_RAT", "id": "O35550-1", "name": "Rab GTPase-binding effector protein 1", "aln": "----MAQPGPAPQPDVSLQQRVAELEKINAEFLRAQQQLEQEFNQKRAKFKELYLAKEEDLKRQNAVLQAAQDDLGHLRTQLWEAQAEMENIKAIATVSENTKQEAIDEVKRQWREEVASLQAVMKETVRDYEHQFHLRLEQERAQWAQYRESADREIADLRRRLSEGQEEENLENEMKKAQEDAEKLRSVVMPMEKEIAALKDKLTEAEDKIKELEASKVKELNHYLEAEKSCRTDLEMYVAVLNTQKSVLQEDAEKLRKELHEVCHLLEQERQQHNQLKHTWQKANDQFLESQRLLMRDMQRMEIVLTSEQLRQVEELKKKDQEEDEQQRINKGKDNKKIDTEEEVKIPVVCALTQEESSTPLSNEEEHLD-STHGSVHSLDADLLLPSGDPFSKSDNDMFKEGLRRAQSTDSLGTSS-SLQSKALG-YNYKAKSAGNLDESDFGPLVGADS-VSENFDTVSLGSLQMPSGFMLTKDQERAIKAMTPEQEETASLLSSVTQGMESAYVSPSGYRLVSETEWNLLQKEVHNAGNKLGRRCDMCSNYEKQLQGIQIQEAETRDQVKKLQLMLRQANDQLEKTMKEKQELEDFLRQSAEDSSHQISALVLRAQASEVLLEELQQSFSQAKRDVQEQMAVLMQSREQVSEELVRLQKDNDSLQGKHSLHVSLQLAEDFILPDTVQVLRELVLKYRENIVHVRTAADHMEEKLKAEILFLKEQIQAEQCLKENLEETLQLEIENCKEEI----ASISSLKAELERIKVEKGQLESTLREKSQQLESLQEIKVNLEEQLKKETAAKATVEQLMFEEKNKAQRLQTELDVSEQVQRDFVKLSQTLQVQLERIRQADSLERIRAILNDTKLTDINQLPET", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O35551-1", "uniprot_id": "RABE1_MOUSE", "id": "O35551-1", "name": "Rab GTPase-binding effector protein 1", "aln": "----MAQPGPAPQPDVSLQQRVAELEKINAEFLRAQQQLEQEFNQKRAKFKELYLAKEEDLKRQNAVLQAAQDDLGHLRTQLWEAQAEMENIKAIATVSENTKQEAIDEVKRQWREEVASLQAIMKETVRDYEHQFHLRLEQERAQWAQYRESAEREIADLRRRLSEGQEEENLENEMKKAQEDAEKLRSVVMPMEKEIAALKDKLTEAEDKIKELEASKVKELNHYLEAEKSCRTDLEMYVAVLNTQKSVLQEDAEKLRKELHEVCHLLEQERQQHNQLKHTWQKANDQFLESQRLLMRDMQRMEIVLTSEQLRQVEELKKKDQEEDEQQRVNKRKDNKKTDTEEEVKIPVVCALTQEESSTPLSNEEEHLD-STHGSVHSLDADLMLPSGDPFSKSDNDMFKDGLRRAQSTDSLGTSS-SLQSKALG-YNYKAKSAGNLDESDFGPLVGADS-VSENFDTVSLGSLQMPSGFMLTKDQERAIKAMTPEQEETASLLSSVTQGMESAYVSPSGYRLVSETEWNLLQKEVHNAGNKLGRRCDMCSNYEKQLQGIQIQEAETRDQVKKLQLMLRQANDQLEKTMKEKQELEDFLKQSAEDSSHQISALVLRAQASEVLLEELQQSFSQAKRDVQEQMAVLMQSREQVSEELVRLQKDNDSLQGKHSLHVSLQLAEDFILPDTVEVLRELVLKYRENIVHVRTAADHMEEKLKAEILFLKEQIQAEQCLKENLEETLQLEIENCKEEI----ASISSLKAELERIKVEKGQLESTLREKSQQLESLQEMKVNLEEQLKKETAAKATVEQLMFEEKNKAQRLQTELDVSEQVQRDFVKLSQTLQVQLERIRQADSLERIRAILNDTKLTDINQLPET", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q15276-1", "uniprot_id": "RABE1_HUMAN", "id": "Q15276-1", "name": "Rab GTPase-binding effector protein 1", "aln": "----MAQPGPASQPDVSLQQRVAELEKINAEFLRAQQQLEQEFNQKRAKFKELYLAKEEDLKRQNAVLQAAQDDLGHLRTQLWEAQAEMENIKAIATVSENTKQEAIDEVKRQWREEVASLQAVMKETVRDYEHQFHLRLEQERTQWAQYRESAEREIADLRRRLSEGQEEENLENEMKKAQEDAEKLRSVVMPMEKEIAALKDKLTEAEDKIKELEASKVKELNHYLEAEKSCRTDLEMYVAVLNTQKSVLQEDAEKLRKELHEVCHLLEQERQQHNQLKHTWQKANDQFLESQRLLMRDMQRMEIVLTSEQLRQVEELKKKDQEDDEQQRLNKRKDHKKADVEEEIKIPVVCALTQEESSAQLSNEEEHLD-STRGSVHSLDAGLLLPSGDPFSKSDNDMFKDGLRRAQSTDSLGTSG-SLQSKALG-YNYKAKSAGNLDESDFGPLVGADS-VSENFDTASLGSLQMPSGFMLTKDQERAIKAMTPEQEETASLLSSVTQGMESAYVSPSGYRLVSETEWNLLQKEVHNAGNKLGRRCDMCSNYEKQLQGIQIQEAETRDQVKKLQLMLRQANDQLEKTMKDKQELEDFIKQSSEDSSHQISALVLRAQASEILLEELQQGLSQAKRDVQEQMAVLMQSREQVSEELVRLQKDNDSLQGKHSLHVSLQQAEDFILPDTTEALRELVLKYREDIINVRTAADHVEEKLKAEILFLKEQIQAEQCLKENLEETLQLEIENCKEEI----ASISSLKAELERIKVEKGQLESTLREKSQQLESLQEIKISLEEQLKKETAAKATVEQLMFEEKNKAQRLQTELDVSEQVQRDFVKLSQTLQVQLERIRQADSLERIRAILNDTKLTDINQLPET", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AB13A9T3-1", "uniprot_id": "A0AB13A9T3_DANRE", "id": "A0AB13A9T3-1", "name": "", "aln": "----MAEQASGSTR--PPQHDGVEQEQDRTDFLKLKQQLEMEFNQKRAKFKELYLSKEEELKRQTAILEKAQAEMCSVQEELADAKAEMETIKAVATLSESTKQEAIDQVKQLWQEEVASLQAIMKDAEREFKLQFQQKLEQERAQWTQYRDGVEREIAELRRRLSEGQEEENLENEMKKAQEDAEKLRSVVMPMESEIAALKAKLSSSEDRVKELEAAKVKELNHVLEAEKSCRTDLEMYVAVLNTQKSVLQEDAEKLRKELHEVVHLLELERQQHNQLKHTWQRANDQFLESQRLLMQDMQRIESVLSSEQLRQVEEIKKRDQEEDEQERLSQAKEASEDDGTEHAEA-------VEDSLLGLSIEESHLSHSIHSSLHSLDAD---TPGRPDS---SDPYKDGLRRVQSTDSLGSSGGSLQPHGLGGHNNKAKSASQLDESDFGPLVGADCGGFDSMDTSSISSLQ-PGHFLLTKDQEKAIKAMTPEQEETASLLSSISHTADTAYLPPSGYRLVSESEWNLLQQELKNAGRKLGRRCDMCSNYEKQLQVIQGQEAETRDQVKKLQAILRQANDQLERTMNEKQELEDSVKQANEDTTAKISELKQKVQESESLFSALQQAFSQAKRNTQEQMAVLLQSREQVSEELNRLQRDNESLQGKHRLHMTLQQQEDFHMPTTVQELQKLVLQYREDIVSARTAAEHLEEKLKAEILFLKEQIQAEQCLKENLEDTLQLEIEGCKEEIDILEASFSSLKTELERVKSEKEQLESSLAEKSQMLESVQRLKNSLEEQLKDTLGSKSALETQVFEEKDKSQRLQAELDVSEQVQRDFVKLSQTLQVQLERIRQAESLDRIRAILNDTNLTDISQLPET", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9W2M0-1", "uniprot_id": "Q9W2M0_DROME", "id": "Q9W2M0-1", "name": "", "aln": "MEENETRSEAREPTDLPNGEDDATSQHKLSHLQNEMRKMQNEFNTQRAKMRELYIQKEAEVSQS--------------QQERRQLQAELDELKTHLMVADLKSQNELQLRDLKAQEEISSLQQLVQDTIEETAH-YKGEVERLRLELGKYQQIQQQTMAQQPQAESSGGIAPQVLNQVKKTLGSVRKLG--TDSLNSSFQQDEDTRASSKGNGKQYAPEEAEMMHSIVEQLQ---EEMKALKVKLREQDEQLQAKSASDESALHKSTSMDVAESACESCSLAEKKTEELGAHINKQQKQVDLLQKQLVESRETLVKEAALRKDLEDQWQEKREAHKSEVQSLR--------------DQAKTNEQRLLD-----------------------------------------------------MQQKFLETKDEVIKQIQRVSDD--------------------------------RERVNKQLETLQADNDFLSGRYLATSEEIDNQYINLPNTVVELQELILRQQSELIQARVSSEYERQKCTSTEDEIQILRAQLEESNNERRAYKRKMQLDIKSLQDRVTEHLVTVQAYETTKTQLERKEAELNKQLSECRVEIIELQEAN-----------EKYAKTNADYKTKIKTLQEELSTMETVQKDFVKLSQTLQMSLEELRHADTEVRWQDDDDVNNCPTCNAYFTVMVRKIHCRHCGHIYCDKCLTKTVPS---------------------------------------------GPRKRVARVCDICHTLLTPNTAPYFSQGQPPQQQQGQQQQQQSN----------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :. . . . . :: :.: . :::: *** :***::***: ** ::.:. : : : :**:: :*: ::: ..*: :: . :**::*** ::::: .: :: .:*: * : :*:: :: :*: : *.* :: *::**: ...** . .::..: : . :.::.. *: . :.: :: :* : ::: . *. *.. ** .: . .. **: : * .. : : .:: *: : : * : * * : ::* ::: :::* : .: .. : . : :* : * : *. .:.:. : :: :::: .::: :. : :. :. *: .. : : *.*: :* . . : *:. *.::* :: * *:.:: : : :: ..*: :.:: : . : : : : * : . .. : **:. ::. : . :: **.: .::: : .:.*. :: : . :: : ::: *. :. :: :* .::**.:.: . : : .: . *. .. : :::.: *: *:: ", "identical_positions": 72, "similar_positions": 273, "identity": "8.24%" }, { "cls_id": "homologset.agr.MGI:1860262", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q91ZF2-1", "uniprot_id": "CAT7_MOUSE", "id": "Q91ZF2-1", "name": "Cathepsin 7", "aln": "------------------------------MTPTVFLSILCLGVALAAPAPDYNLDAEWEEWKRSNDRTYSPEEEKQ-RRAVWEGNVKWIKQHIMENGLWMNNFTIEMNEFGDMTGEEMKMLTESSSYPLRNGK-----------HIQKRNPKIPPTLDWRKEGYVTPVRRQGSCGACWAFSVTACIEGQLFKKTGKLIPLSVQNLMDCSVSYGTKGCDGGRPYDAFQYVKNNGGLEAEATYPYEAKAKH-CRYRPERSVVKVNRFFVVPR-NEEALLQALVTHGPIAVAIDGSHASFHSYRGGIYHEPKCRKDTLDHGLLLVGYGYEGHESENRKYWLLKNSHGERWGENGYMKLPRGQNNYCGIASYAMYPAL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D3ZZ07-1", "uniprot_id": "CAT7_RAT", "id": "D3ZZ07-1", "name": "Cathepsin 7", "aln": "------------------------------MTVAVFLAILCLRAALAAPRPDYSLDAEWEEWKRNNAKTYSPEEEKQ-RRAVWEENVKMIKWHTMQNGLWMNNFTIEMNEFGDMTGEEMRMMTDSSALTLRNGK-----------HIQKRNVKIPKTLDWRDTGCVAPVRSQGGCGACWAFSVAASIESQLFKKTGKLIPLSVQNLIDCTVTYGNNDCSGGKPYTAFQYVKNNGGLEAEATYPYEAKLRH-CRYRPERSVVKIARFFVVPR-NEEALMQALVTYGPIAVAIDGSHASFKRYRGGIYHEPKCRRDTLDHGLLLVGYGYEGHESENRKYWLLKNSHGEQWGERGYMKLPRDQNNYCGIASYAMYPLL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "M0RDV7-1", "uniprot_id": "M0RDV7_RAT", "id": "M0RDV7-1", "name": "Cathepsin 7", "aln": "------------------------------MTPAVFLVILWLGVTLAAPTPDYNLDAEWEKWKRSNEKTYSPEEEEQ-RRALWEENVKMIKQHTVENGLWMNNFTIEMNQFCDMTDEEMRMMIDSSAPTLRKEK-----------RVQKRNVEIPKTLDWRKDGYVTPVRRQGACGACWGFAVAGSIEGQLFKKTGKLSPLSVQNLVDCSRSFGTMGCNGGRIYNAFQYVKNNGGLEAEATYPYEAKVRN-CRYRPEKSVVKVTRFLVVPR-NEEALINALVNIGPIAVGIDAQHESFKKYAGGIYHEPNCKRDSPNHSMLLVGFGYEGQESEGRKYWLVKNSYGEQWGEKGYMKIPRGQNNYCGIASYAMYPVL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q95029-1", "uniprot_id": "CATL1_DROME", "id": "Q95029-1", "name": "Cathepsin L1", "aln": "MNHLGVFETRFRPRTRHKSQRAQLIPEQITMRTAVLLPLLALLAVAQAVSFADVVMEEWHTFKLEHRKNYQDETEERFRLKIFNENKHKIAKHNQRFAEGKVSFKLAVNKYADLLHHEFRQLMNGFNYTLHKQLRAADESFKGVTFISPAHVTLPKSVDWRTKGAVTAVKDQGHCGSCWAFSSTGALEGQHFRKSGVLVSLSEQNLVDCSTKYGNNGCNGGLMDNAFRYIKDNGGIDTEKSYPYEAIDDS-CHFNKGTVGATDRGFTDIPQGDEKKMAEAVATVGPVSVAIDASHESFQFYSEGVYNEPQCDAQNLDHGVLVVGFG---TDESGEDYWLVKNSWGTTWGDKGFIKMLRNKENQCGIASASSYPLV", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "A0A8M1NEU9-1", "uniprot_id": "A0A8M1NEU9_DANRE", "id": "A0A8M1NEU9-1", "name": "", "aln": "-------------------------------MMFALLVTLCISAVFAASSIDIQLDDHWNSWKSQHGKSYHEDVEVG-RRMIWEENLKKIEQHNFEYSYGNHTFKMGMNQFGDMTNEEFRQAMNGYKHDPNRTS-------QGPLFMEPSFFAAPQQVDWRQRGYVTPVKDQKQCGSCWSFSSTGALEGQLFRKTGKLISMSEQNLVDCSRPQGNQGCNGGLMDQAFQYVKENKGLDSEQSYPYLARDDLPCRYDPRFNVAKITGFVDIPRGNELALMNAVAAVGPVSVAIDASHQSLQFYQSGIYYERACSSSRLDHAVLVVGYGYQGADVAGNRYWIVKNSWSDKWGDKGYIYMAKDKNNHCGVATTASYPLM", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .:* * : .. * : .*. :* .: :.* : * * ::: * : * * . . .*.: :*:: *: .*:: :. .. :. * :*** * *:.*: * **:**.*: :..:*.* *:*:* * .:* ***:**: *. .*.** **:*:*:* *:::* :*** * *:: .. * :*: :* : :*:. **::*.**..* *:: * *:* * * . :*.:*:**:* : .. **::*** . **:.*:: : :.::* **:*: : ** :", "identical_positions": 91, "similar_positions": 108, "identity": "24.27%" }, { "cls_id": "homologset.agr.MGI:1860263", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0ABK0LCE3-1", "uniprot_id": "A0ABK0LCE3_RAT", "id": "A0ABK0LCE3-1", "name": "Proteasome assembly chaperone 1", "aln": "MAATFFGEVVKGPCRAGTEEEEEEEEQSRRDTPEDREVRRKLARKREVKLLRRQTETCLEAVLLEKHPCSKFILAVGSNATAFLSSFVMNSGVWEEVGCAKLWNEWCRTTD--TVHLSPTDVFCVFYQLKSDPSVLLCQCSCYIAEDQQFQWLEKVFGFRPRKNMQVTVLTCRHITEYKTCESTYNLSSPFLRALKTQKFKDTVYCPLLEQPNIVHGLSAAVLSYCQVWKVPAVLYVCYTDVMKLDLVTVEAFKPIFSSRSLKCLVKNIPESTEILKKLMTTNEIQSNIYT", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9JK23-1", "uniprot_id": "PSMG1_MOUSE", "id": "Q9JK23-1", "name": "Proteasome assembly chaperone 1", "aln": "MAATFFGEVVKAPCRAGTEEEEEEEEQSRRDTPEDREVRRQLARKREVRLLRRQTETSLEAVLLETHPCSKFIIAVGSNATAFLSAFVMNSGVWEEVGCAKLWNEWCRTTD--TVRLSPTDVFCVFYQLKSDPSVFLCQCSCYIAEDQQFQWLEKVFGFQPRKSMQVTVLTCRHITDYKTPESTCSLSSPFLRALKTQTFKDALCCPLLEQPNIVHDLSAAVLSYCQVWKIPAVLYLCYTDVMKLDRVTVEAFKPLLSSRSLKCLVKNIPESTEILKKLMTTNEIQSNIYT", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O95456-1", "uniprot_id": "PSMG1_HUMAN", "id": "O95456-1", "name": "Proteasome assembly chaperone 1", "aln": "MAATFFGEVVKAPCRAGTEDEEEEEE-GRRETPEDREVRLQLARKREVRLLRRQTKTSLEVSLLEKYPCSKFIIAIGNNAVAFLSSFVMNSGVWEEVGCAKLWNEWCRTTD--TTHLSSTEAFCVFYHLKSNPSVFLCQCSCYVAEDQQYQWLEKVFGSCPRKNMQITILTCRHVTDYKTSESTGSLPSPFLRALKTQNFKDSACCPLLEQPNIVHDLPAAVLSYCQVWKIPAILYLCYTDVMKLDLITVEAFKPILSTRSLKGLVKNIPQSTEILKKLMTTNEIQSNIYT", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6DG91-1", "uniprot_id": "PSMG1_DANRE", "id": "Q6DG91-1", "name": "Proteasome assembly chaperone 1", "aln": "-MATFFGEVLSVYSRAVEEDEYEDMT---NENEEDEQIRREIEEKRSVEVCW------LLGSQDGPLQCSDLIIGAGPNASGFIRAYLLSTVGWTAVAWLSFWNERSRGSERPTVVPGPGEPSCVLYRLESCPTVLICQCQGFVAEDQLFQFTEKVFSCVQTRDLNVTILSDCSSADYKTSDYLSGSSTPFLRCLKTSTYTHTVTCPPLEQPNICSGLAAAVLSHCQVHQISAVLYQCYSDVLHPDSASMQMFAATLSS----VLKLEQSLSADVLQRVTRVSEIQSNLYT", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *******:. .** *:* *: .:. **.::* :: .**.*.: * **.:*:. * ** .*: ::::.: * *. .:*** .* :: *. .. : **:*:*:* *:*::***. ::**** :*: ****. :.:::*:*: ::*** : . .:****.***..:..: ** ****** .*.*****:*** ::.*:** **:**:: * ::: * . :*: * : . *:::*::: ..*****:**", "identical_positions": 101, "similar_positions": 98, "identity": "34.71%" }, { "cls_id": "homologset.agr.MGI:1860267", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9EQU5-1", "uniprot_id": "SET_MOUSE", "id": "Q9EQU5-1", "name": "Protein SET", "aln": "MAPKRQSAILPQPKKPRPAAAPKLEDKSASPGLPK-GEKEQQEAIEHIDEVQNEIDRLNEQASEEILKVEQKYNKLRQPFFQKRSELIAKIPNFWVTTFVNHPQVSALLGEEDEEALHYLTRVEVTEFEDIKSGYR-----IDFYFD-ENPYFENKVLSKEFHLN-----ESGD-PSSKSTEIKWKSGKDLTKRSSQTQNKA--SRKRQHEEPESFFTWF------TDHSDAGADELGEVIKDDIWPNPLQYYLVPDMDDEEGEAEDDDDDDEEEEG---LEDIDEEGDEDEGEEDDDEDEGEEGEEDEGEDD", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q63945-1", "uniprot_id": "SET_RAT", "id": "Q63945-1", "name": "Protein SET", "aln": "MAPKRQSAILPQPKKPRPVAAPKLEDKSASPGLPK-GEKEQQEAIEHIDEVQNEIDRLNEQASEEILKVEQKYNKLRQPFFQKRSELIAKIPNFWVTTFVNHPQVSALLGEEDEEALHYLTRVEVTEFEDIKSGYR-----IDFYFD-ENPYFENKVLSKEFHLN-----ESGD-PSSKSTEIKWKSGKDLTKRSSQTQNKA--SRKRQHEEPESFFTWF------TDHSDAGADELGEVIKDDIWPNPLQYYLVPDMDDEEGEAEDDDDDDEEEEG---LEDIDEEGDEDEGEEDDDEDEGEEGEEDEGEDD", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q01105-1", "uniprot_id": "SET_HUMAN", "id": "Q01105-1", "name": "Protein SET", "aln": "MAPKRQSPLPPQKKKPRPPPALGPEETSASAGLPKKGEKEQQEAIEHIDEVQNEIDRLNEQASEEILKVEQKYNKLRQPFFQKRSELIAKIPNFWVTTFVNHPQVSALLGEEDEEALHYLTRVEVTEFEDIKSGYR-----IDFYFD-ENPYFENKVLSKEFHLN-----ESGD-PSSKSTEIKWKSGKDLTKRSSQTQNKA--SRKRQHEEPESFFTWF------TDHSDAGADELGEVIKDDIWPNPLQYYLVPDMDDEEGEGEEDDDDDEEEEG---LEDIDEEGDEDEGEEDEDDDEGEEGEEDEGEDD", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P0DME0-2", "uniprot_id": "SETLP_HUMAN", "id": "P0DME0-2", "name": "Protein SETSIP", "aln": "MAPKRQSPLPLQKKKPRPPPALGLEETSASAGLPKKGEKEQQEAIEHIDEVQNEIDRLNEQDSEEILKVEQKYNKLRQPFFQKRSELIAKIPNFGVTTFVNHPQVSSLLGEEDEEALHYLTKVEVTEFEDIKSGYR-----IDFYFD-ENPYFENKVFSKEFHLN-----ESGD-PSSKSTKIKWKSGKDVTKRSSQTQNKA--SRKRQHEEPESFFTWF------TDHSDAGADELEEVIKDDIWPNPLQYYLVPDMDDEEGGEDDDDDDDDGDEGEEELEDIDE-GDEDEGEEDEDDDEGEEGEEDEGEDD", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P53997-1", "uniprot_id": "SET_DROME", "id": "P53997-1", "name": "Protein SET", "aln": "--------MSSVPKRAKLDGAPADGNTSAAAGNNE----EESEALEQIDACQNEIDALNEKASEEILKVEQKYNKLRKPCYEKRSELVKRIPNFWVTSFINHPQVSGILDEEEEECLHALNKLEVEEFEDIKSGYR-----INFHFD-ENPYFENKVLTKEFHLNSAAASENGDWPASTSTPIKWKEGKNLLK-LLLTKPYG--NKKKRNSEYKTFFDWF------SDNTDPVNDEIAELIKDDLWPNPLQYYLVPDIEVEPEDEEDNEDNDE--------EAFDD--------EDGEDGEGEEEEEDEDDK-", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P53853-1", "uniprot_id": "VPS75_YEAST", "id": "P53853-1", "name": "Vacuolar protein sorting-associated protein 75", "aln": "--------MMSDQENEN----------------------EHAKAFLGLAKCEEEVDAIER-------EVELYRLNKMKPVYEKRDAYIDEIAEFWKIVLSQHVSFANYIRASDFKYIDTIDKIKVEWLALESEMYDTRDFSITFHFHGIEGDFKEQQVTKVFQIKKGKDDQEDGILTSEPVPIEWPQSYDSINPDLIKDKRSPEGKKKYRQGMKTIFGWFRWTGLKPGKEFPHGDSLASLFSEEIYPFCVKYYAEAQRDLEDEEGESGLSADG--------DSEDDDGSLGEVDLPLSDEEPSSKKRKV----", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : :. . *. :*: : ::*:* ::. :** : :* ::**. : .*.:* : :* ..: : .: : :. : :::* : .. * * *:*. : *::: .:* *::: :... :* .. *:* .. : : .. . .:*: .. :::* ** ..: . *.: .::.::::* ::** .: : * :.. . * : *: .: * .. :.. ", "identical_positions": 35, "similar_positions": 108, "identity": "11.18%" }, { "cls_id": "homologset.agr.MGI:1860275", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZP54-1", "uniprot_id": "D3ZP54_RAT", "id": "D3ZP54-1", "name": "", "aln": "------------------------------MSPVVLLAILCLGVARATQPSD-----------------------------------------------------PSLDSEWQEWKTKYEKNYSLE-EEGQKRAVWEENMKVVKQHNIEYDQEKKNFTMELNAFADMTGEEFRKMMTNIPV---------QNLRKKKSIHQPIFRYLPKFVDWRRRGYVTSVKNQGTCNSCWAFSVAGAIEGQMFRKTGRLVSLSPQNLVDCSRPE--GNHGCHMGSTLYALKYVWSNG-GLEAESTYPYEGKEGP-CRYLPRRSAARVTGFSTVAR-SEEALMHAVATIGPISVGIDASHVSFRFYRRGIYYEPRCSSNRINHSVLVVGYGYEGRESDGRKYWLIKNSHGVGWGMNGYMKLARGWNNHCGIATYGFYPRV", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0A8I6GGT8-1", "uniprot_id": "A0A8I6GGT8_RAT", "id": "A0A8I6GGT8-1", "name": "", "aln": "------------------------------MSPFVLLTILCLAVARDTQSSD-----------------------------------------------------PSLDSEWQEWKIKYDKNYSLE-EEGQRRAVWEENMKVVKQHNIEYDQGKNNFTMKVNAFGDMTGEEFRKMMIDIPS---------HTGG-----------YLPKFVDWRRRGYVTSVKNQGRCNSCWAFSVAGAIEGQMFRKTGRLVSLSAQNLVDCSRPE--GNRGCISGHTFYTFKYVWNNG-GLEAESTYPYEGREGH-CRYLPERSAARIKGFSIISS-TEEALMNAVATIGPISVGIDASHESFTFYSGGIYYEPKCRNKTVNHAVLLVGYGYEGRESDGRKYWLIKNSHGVGWGMNGYMKLARGWNKHCGIATCAFYPRV", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9JI81-1", "uniprot_id": "CAT8_MOUSE", "id": "Q9JI81-1", "name": "Cathepsin 8", "aln": "------------------------------MGPAVLLAILCLGVAEVTQSSD-----------------------------------------------------PSLDSEWQEWKRKFNKNYSME-EEGQKRAVWEENMKLVKQHNIEYDQGKKNFTMDVNAFGDMTGEEYRKMLTDIPV---------PNFRKKKSIHQPIAGYLPKFVDWRKRGCVTPVKNQGTCNSCWAFSAAGAIEGQMFRKTGKLVPLSTQNLVDCSRLE--GNFGCFKGSTFLALKYVWKNR-GLEAESTYPYKGTDGH-CRYHPERSAARITSFSFVSN-SEKDLMRAVATIGPISVGIDARHKSFRLYREGIYYEPKCSSNIINHSVLVVGYGYEGKESDGNKYWLIKNSHGEQWGMNGYMKLARGRNNHCGIASYAVYPRV", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P07711-1", "uniprot_id": "CATL1_HUMAN", "id": "P07711-1", "name": "Procathepsin L", "aln": "------------------------------MNPTLILAAFCLGIASATLTFD-----------------------------------------------------HSLEAQWTKWKAMHNRLYGMN-EEGWRRAVWEKNMKMIELHNQEYREGKHSFTMAMNAFGDMTSEEFRQVMNGFQN---------RKPRKGKVFQEPLFYEAPRSVDWREKGYVTPVKNQGQCGSCWAFSATGALEGQMFRKTGRLISLSEQNLVDCSGPQ--GNEGCNGGLMDYAFQYVQDNG-GLDSEESYPYEATEES-CKYNPKYSVANDTGFVDIPK-QEKALMKAVATVGPISVAIDAGHESFLFYKEGIYFEPDCSSEDMDHGVLVVGYGFESTESDNNKYWLVKNSWGEEWGMGGYVKMAKDRRNHCGIASAASYPTV", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1NEU9-1", "uniprot_id": "A0A8M1NEU9_DANRE", "id": "A0A8M1NEU9-1", "name": "", "aln": "-------------------------------MMFALLVTLCISAVFAASSID-----------------------------------------------------IQLDDHWNSWKSQHGKSYHED-VEVGRRMIWEENLKKIEQHNFEYSYGNHTFKMGMNQFGDMTNEEFRQAMNGYKHDP-------NRTSQGPLFMEPSFFAAPQQVDWRQRGYVTPVKDQKQCGSCWSFSSTGALEGQLFRKTGKLISMSEQNLVDCSRPQ--GNQGCNGGLMDQAFQYVKENK-GLDSEQSYPYLARDDLPCRYDPRFNVAKITGFVDIPRGNELALMNAVAAVGPVSVAIDASHQSLQFYQSGIYYERACSSSRLDHAVLVVGYGYQGADVAGNRYWIVKNSWSDKWGDKGYIYMAKDKNNHCGVATTASYPLM", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q95029-1", "uniprot_id": "CATL1_DROME", "id": "Q95029-1", "name": "Cathepsin L1", "aln": "MNHLGVFETRFRPRTRHKSQRAQLIPEQITMRTAVLLPLLALLAVAQAVSFA-----------------------------------------------------DVVMEEWHTFKLEHRKNYQDETEERFRLKIFNENKHKIAKHNQRFAEGKVSFKLAVNKYADLLHHEFRQLMNGFNYTLHKQLRAADESFKGVTFISPAHVTLPKSVDWRTKGAVTAVKDQGHCGSCWAFSSTGALEGQHFRKSGVLVSLSEQNLVDCSTKY--GNNGCNGGLMDNAFRYIKDNG-GIDTEKSYPYEAIDDS-CHFNKGTVGATDRGFTDIPQGDEKKMAEAVATVGPVSVAIDASHESFQFYSEGVYNEPQCDAQNLDHGVLVVGFG---TDESGEDYWLVKNSWGTTWGDKGFIKMLRNKENQCGIASASSYPLV", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "A1ZAU4-1", "uniprot_id": "A1ZAU4_DROME", "id": "A1ZAU4-1", "name": "", "aln": "MQSNIISASPFHPSTTKPVGTNSFVFWQISMKLLLVLPLLVAVVSGQGFGGGGFGGGFGGGLGGGFGGGLGGLGNNRVGGALQNVAGAVQNAVGNIAKAVPKVPLLSNVQDFGDFLSQSGKTYLSAADRALHEGAFASTKNLVEAGNAAFAQGVHTFKQAVNAFADLTHSEFLSQLTGLKRSPE----AKARAAASLKLVNLPAKPIPDAFDWREHGGVTPVKFQGTCGSCWAFATTGAIEGHTFRKTGSLPNLSEQNLVDCGPVEDFGLNGCDGGFQEAAFCFIDEVQKGVSQEGAYPYIDNKGT-CKYDGSKSGATLQGFAAIPPKDEEQLKKVVATLGPVACSVNG-LETLKNYAGGIYNDDECNKGEPNHSILVVGYG----SEKGQDYWIVKNSWDDTWGEKGYFRLPRGK-NYCFIAEECSYPVV", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VKY4-1", "uniprot_id": "Q9VKY4_DROME", "id": "Q9VKY4-1", "name": "cathepsin L", "aln": "---------------------------MWKLIFFGCLCGLNCQIVTSNLSEG-------------------------------------------------NSSSANCKSEFEKFKNNNNRKYLRTYDEMRSYKAFEENFKVIEEHNQNYKEGQTSFRLKPNIFADMSTDGYLKGFLRLLKSN----IEDSADNMAEIVGSPLMANVPESLDWRSKGFITPPYNQLSCGSCYAFSIAESIMGQVFKRTGKILSLSKQQIVDCSVSH--GNQGCVGGSLRNTLSYLQSTG-GIMRDQDYPYVARKGK-CQFVPDLSVVNVTSWAILPVRDEQAIQAAVTHIGPVAISINASPKTFQLYSDGIYDDPLCSSASVNHAMVVIGFG--------KDYWILKNWWGQNWGENGYIRIRKGV-NMCGIANYAAYAIV", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * : .: : : * . : .. : : * : .* * :.*: : . : * .*** :* :*. * *.**::*: : :: *: *:::* : :* *::***. * ** * :: :: . *: : *** . *:: . .: :. * : .*: :**:: .::. :: * *:* : * :*.::::*:* . **::** . ** *:. : :. : * :* *. :", "identical_positions": 55, "similar_positions": 88, "identity": "12.76%" }, { "cls_id": "homologset.agr.MGI:1860276", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8R317-1", "uniprot_id": "UBQL1_MOUSE", "id": "Q8R317-1", "name": "Ubiquilin-1", "aln": "MAESAESGGPPGAQDSAADGG---------PAEPKIMKVTVKTPKEKEEFAVPENSSVQQFKEEISKRFKSHIDQLVLIFAGKILKDQDTLSQHGIHDGLTVHLVIKTQNRPQDNSAQQTNAPGSTVTSSPAPDSNPTSGSAANSSFGVGGLGGLAGLSSLGLNTTNFSELQSQMQRQLLSNPEMMVQIMENPFVQSMLSNPDLMRQLIMANPQMQQLIQRNPEISHMLNNPDIMRQTLELARNPAMMQEMMRNQDRALSNLESIPGGYNALRRMYTDIQEPMLNAAQEQFGGNPFASLVSSSSSAEGTQPSR-TENRDPLPNPWAPQTSQSSPASGTTGSTTNTMSTSGGTATSTPAGQSTSGPSLVPGAGASMFNTPGMQSLLQQITENPQLMQNMLSAPYMRSMLQSLSQNPDLAAQMMLNNPLFAGNPQLQEQMRQQLPTFLQQMQNPDTLSAMSNPRAMQALLQIQQGLQTLATEAPGLIP--GFTPGL-AAGN---------SGGSSGTNAPSTAPSE---------DTNPQGGTAEPGHQQFIQQMLQALAGVNPQLQSPEVRFQQQLEQLSAMGFLNREANLQALIATGGDINAAIERLLGS-QPS--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9JJP9-1", "uniprot_id": "UBQL1_RAT", "id": "Q9JJP9-1", "name": "Ubiquilin-1", "aln": "MAESAESGGPPGAQDSAADSG---------PAEPKIMKVTVKTPKEKEEFAVPENSSVQQFKEEISKRFKSHIDQLVLIFAGKILKDQDTLSQHGIHDGLTVHLVIKTQNRPQDNSAQQTNTTGNSVTSSPAPDSNPTSGPAANSSFGLGGLGGLAGLSSLGLNTTNFSELQSQMQRQLLSNPEMMVQIMENPFVQSMLSNPDLMRQLIMANPQMQQLIQRNPEISHMLNNPNIMRQTLELARNPAMMQEMMRNQERDLSNLESIPGGYNALRRMYTDIQEPMLNAAQEQFGGNPFASLVSSPSSAEGTQPSR-TENRDPLPNPWAPQTPQSSPASGSTGSTTNTVSTSAGNATSTPAGQGTSGPNLVPGAGASMFNTPGMQSLLQQITENPQLMQNMLSAPYMRSMMQSLSQNPDLAAQMMLNNPLFAGNPQLQEQMRQQLPTFLQQMQNPDTLSAMSNPRAMQALLQIQQGLQTLATEAPGLIP--GFTPGL-AAGN---------SGGPAGTTAPSTAPGE---------DTNPQGGAAEPGHQQFIQQMLQALAGVNPQLQSPEVRFQQQLEQLSAMGFLNREANLQALIATGGDINAAIERLLGS-QPS--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9UMX0-1", "uniprot_id": "UBQL1_HUMAN", "id": "Q9UMX0-1", "name": "Ubiquilin-1", "aln": "MAESGESGGPPGSQDSAAGAEGAGAPAAAASAEPKIMKVTVKTPKEKEEFAVPENSSVQQFKEEISKRFKSHTDQLVLIFAGKILKDQDTLSQHGIHDGLTVHLVIKTQNRPQDHSAQQTNTAGSNVTTSSTPNSNSTSGSATSNPFGLGGLGGLAGLSSLGLNTTNFSELQSQMQRQLLSNPEMMVQIMENPFVQSMLSNPDLMRQLIMANPQMQQLIQRNPEISHMLNNPDIMRQTLELARNPAMMQEMMRNQDRALSNLESIPGGYNALRRMYTDIQEPMLSAAQEQFGGNPFASLVSNTSSGEGSQPSR-TENRDPLPNPWAPQTSQSSSASSGTASTVG--GTTGSTASGT-SGQSTTAPNLVPGVGASMFNTPGMQSLLQQITENPQLMQNMLSAPYMRSMMQSLSQNPDLAAQMMLNNPLFAGNPQLQEQMRQQLPTFLQQMQNPDTLSAMSNPRAMQALLQIQQGLQTLATEAPGLIP--GFTPGLGALGS---------TGGSSGTNGSNATPSE---------NTSPTAGTTEPGHQQFIQQMLQALAGVNPQLQNPEVRFQQQLEQLSAMGFLNREANLQALIATGGDINAAIERLLGS-QPS--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VWD9-1", "uniprot_id": "Q9VWD9_DROME", "id": "Q9VWD9-1", "name": "Ubiquilin-like protein", "aln": "MAE----GGS------------------------KRINVVVKTPKDKKTVEVDEDSGIKDFKILVAQKFEAEPEQLVLIFAGKIMKDTDTLQMHNIKDNLTVHLVIKAPTRNNEQPARQP-------------------ADVRQTPFGLNQFGGLAGMEALGAGSNTFMDLQARMQNELLNNGDMLRSLMDNPMVQQMMNNPDTMRQLITSNPQMHDLMQRNPEISHMLNNPDLLRQTMELARNPSMLQELMRSHDRAMSNLESVPGGYSALQRIYRDIQEPMMNAATESFGRNPFAGLVDGGGSGAGNNPQQGTENRNPLPNPWGGANSGTNGTVGGSG-----------------AGNPTG--DLPP---NNVLNTPAMRSLLQQMADNPAMMQNLLNAPYTRSMMESMSQDPDMAARLLSSSPLMSNNPALQEQVRQMMPQFMAQMQNPEVMNMLTNPDAMNAILQIQQGMEQLRSAAPGLVGTLGIPPPPPGAGTGTNPASGDGSGGNSGASTNNVSPSSGLNAGTGTPNLAPGGGPNAQLFNDFMMRMLNGMSNNADNTQPPEVRYQSQLEQLNAMGFVNRDANLQALIATFGDINAAVERLLSLNQLSLS", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P48510-1", "uniprot_id": "DSK2_YEAST", "id": "P48510-1", "name": "Ubiquitin domain-containing protein DSK2", "aln": "----------------------------------MSLNIHIKSGQDKWEVNVAPESTVLQFKEAINKANGIPVANQRLIYSGKILKDDQTVESYHIQDGHSVHLVKSQPKPQTASAAGANN------------------ATATGAAAGTGATPNMSSGQSAGFN--PLADLTSARYAGYLN---MPSADMFGPDGGALNNDSNNQDELLR-----------------MMENPIFQSQMNEMLSNPQMLDFMIQ------SNPQLQAMGPQARQMLQSPMFRQMLTNPDMIRQSMQFARMMDPN---AGMGSAGGAASAFPAPGGDAPEEGSNTNTTSSSN-----------------TGNNAG------------------------TNAGTNAGANTAANPFASLLNPALN-------------PFANAGNAASTGMPAFDPALLASMFQP------------------------------------------------------------------------------------------------------PVQASQAEDTRPPEERYEHQLRQLNDMGFFDFDRNVAALRRSGGSVQGALDSLLNGDV----", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ::: :*: ::* . * :* : :** : : : **::***:** :*:. : *:*. :**** . . .* . . . * . .::. .: * . : :* : *. * * .* : .:.: :*: *::** : * *: ** *:: ::: ** : . * .* : : : . *:. . ** ::. * . : . * *. . .. : . : :*: : .. * *: : ::. *: . . : * :: .* :* :. : : ** *:: **.**. ***.: : *: ** : *.::.*:: **. ", "identical_positions": 71, "similar_positions": 120, "identity": "11.53%" }, { "cls_id": "homologset.agr.MGI:1860283", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9QZM0-1", "uniprot_id": "UBQL2_MOUSE", "id": "Q9QZM0-1", "name": "Ubiquilin-2", "aln": "MAENGESSGPPRPSRGPAAAPGAASPPAEPKIIKVTVKTPKEKEEFAVPENSTVQQFKEAISKRFKSQTDQLVLIFAGKILKDQDTLMQHGIHDGLTVHLVIKSQNRPQGQATTQPSTTAGTSTTTTTTTTAAAP-AATTSSAPRSSSTPTTTNSSSFGLGSLSSLS---NLGLNSPNFTELQNQMQQQLLASPEMMIQIMENPFVQSMLSNPDLMRQLIMANPQMQQLIQRNPEISHLLNNPDIMRQTLEIARNPAMMQEMMRNQDLALSNLESIPGGYNALRRMYTDIQEPMLNAAQEQFGGNPFATVGSSSTSGEGTQPSR-TENRDPLPNPWAPPPTTQTAATTTTTTTTSSGSGSGSSSSSTTAGNTMAAANYVASIFSTPGMQSLLQQITENPQLIQNMLSAPYMRSMMQSLSQNPDMAAQMMLSSPLFTSNPQLQEQMRPQLPNFLQQMQNPETIAAMSNPRAMQALMQIQQGLQTLATEAPGLIPSFAPGVGMGVLGTAITPVGPVTPIGPIGPIVPFTPIGPIGPIGPTGPASSPGSTGTGIPPATTVSSSAPTETISPTSESGPNQQFIQQMVQALTGGSPPQPPNPEVRFQQQLEQLNAMGFLNREANLQALIATGGDINAAIERLLGS-QPS--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D4AA63-1", "uniprot_id": "D4AA63_RAT", "id": "D4AA63-1", "name": "", "aln": "MAENGESSGPPRPSRGPAAAPGAANPPAEPKIIKVTVKTPKEKEEFAVPENSTVQQFKEAISKRFKSQTDQLVLIFAGKILKDQDTLIQHGIHDGLTVHLVIKSQNRPQGQATTQPSTTAGTSTTTTTTTTAAAPPAATTSSAPRCSTTATTTNSSNLGLGSLASLG---NLGLNSSNFTELQNQMQQQLLASPEMMIQIMENPFVQSMLSNPDLMRQLIMANPQMQQLIQRNPEISHLLNNPDIMRQTLEIARNPAMMQEMMRNQDLALSNLESIPGGYNALRRMYTDIQEPMLNAAQEQFGGNPFATVGSSSSSGEGTQPSR-TENRDPLPNPWAPPPTTQTSATTTTTTTSS-GTVAGSNTSSTTAGNTMAAANYVASIFSTPGMQSLLQQITENPQLIQNMLSAPYMRSMMQSLSQNPDMAAQMMLSSPLFTANPQLQEQMRPQLPNFLQQMQSPETIAAMSNPRAMQALLQIQQGLQTLATEAPGLIPGFTPGVGVGVLGTAITPVGPVTPIGPIGPIVPFTPIGPIGPIGPTGPASSPGSTGTGIPPATTVSSSAPTETISPTSESGPSQQFIQQMVQALTGGSPPQPPNPEVRFQQQLEQLNAMGFLNREANLQALIATGGDINAAIERLLGS-QPS--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9UHD9-1", "uniprot_id": "UBQL2_HUMAN", "id": "Q9UHD9-1", "name": "Ubiquilin-2", "aln": "MAENGESSGPPRPSRGPAAAQGSAAAPAEPKIIKVTVKTPKEKEEFAVPENSSVQQFKEAISKRFKSQTDQLVLIFAGKILKDQDTLIQHGIHDGLTVHLVIKSQNRPQGQS-TQPSNAAGTNTTS--------------ASTPRSNSTPISTNSNPFGLGSLGGLAGLSSLGLSSTNFSELQSQMQQQLMASPEMMIQIMENPFVQSMLSNPDLMRQLIMANPQMQQLIQRNPEISHLLNNPDIMRQTLEIARNPAMMQEMMRNQDLALSNLESIPGGYNALRRMYTDIQEPMLNAAQEQFGGNPFASVGSSSSSGEGTQPSR-TENRDPLPNPWAPPPATQSSATTSTTTSTG--SGSG-NSSSNATGNTVAAANYVASIFSTPGMQSLLQQITENPQLIQNMLSAPYMRSMMQSLSQNPDLAAQMMLNSPLFTANPQLQEQMRPQLPAFLQQMQNPDTLSAMSNPRAMQALMQIQQGLQTLATEAPGLIPSFTPGVGVGVLGTAIGPVGPVTPIGPIGPIVPFTPIGPIGPIGPTGPAAPPGSTGSGGPTGPTVSSAAPSETTSPTSESGPNQQFIQQMVQALAGANAPQLPNPEVRFQQQLEQLNAMGFLNREANLQALIATGGDINAAIERLLGS-QPS--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VWD9-1", "uniprot_id": "Q9VWD9_DROME", "id": "Q9VWD9-1", "name": "Ubiquilin-like protein", "aln": "MAEGG------------------------SKRINVVVKTPKDKKTVEVDEDSGIKDFKILVAQKFEAEPEQLVLIFAGKIMKDTDTLQMHNIKDNLTVHLVIKAPTRNNEQPARQPADVRQT----------------------------------PFGLNQFGGLAGMEALGAGSNTFMDLQARMQNELLNNGDMLRSLMDNPMVQQMMNNPDTMRQLITSNPQMHDLMQRNPEISHMLNNPDLLRQTMELARNPSMLQELMRSHDRAMSNLESVPGGYSALQRIYRDIQEPMMNAATESFGRNPFAGLVDGGGSGAGNNPQQGTENRNPLPNPWG-------GANSGTNGTVG-GSGAGNPTGDLPPNN----------VLNTPAMRSLLQQMADNPAMMQNLLNAPYTRSMMESMSQDPDMAARLLSSSPLMSNNPALQEQVRQMMPQFMAQMQNPEVMNMLTNPDAMNAILQIQQGMEQLRSAAPGLV---------GTLGIPPPPPGAGTGTN---------PASGDGSGGNSGASTNNVSPSSGLNAGTGTPNLAP----GGGPNAQLFNDFMMRMLNGMSNNADNTQP-PEVRYQSQLEQLNAMGFVNRDANLQALIATFGDINAAVERLLSLNQLSLS", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P48510-1", "uniprot_id": "DSK2_YEAST", "id": "P48510-1", "name": "Ubiquitin domain-containing protein DSK2", "aln": "------------------------------MSLNIHIKSGQDKWEVNVAPESTVLQFKEAINKANGIPVANQRLIYSGKILKDDQTVESYHIQDGHSVHLVK-SQPKPQTASAAGANNATATG--------------------------------AAAGTGATPNMS-----SGQSAGFNPLADLTSARYAGYLNMPSADMFGPDGGALNNDSNNQDELLR-----------------MMENPIFQSQMNEMLSNPQMLDFMIQ------SNPQLQAMGPQARQMLQSPMFRQMLTNPDMIRQSMQFARMMDPN---AGMGSAGGAASAFPAPGGDAPEEGSNTNTTSSSNTGNNAGTNAGTNAGANTAAN-------------------------------------PFASLLNPALN-------------PFANAGNAASTGMPAFDPALLASMFQP-----------------------------------------------------------------------------------------------------------------------------PVQASQAEDTRPPEERYEHQLRQLNDMGFFDFDRNVAALRRSGGSVQGALDSLLNGDV----", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ::: :*: ::* . * :* : :** : : : **::***:** :*: : *:*. :**** : : : . . . * * . .:. . * * * . . :* * .* : .:.: :*: :::** : * *: ** *:: ::: ** : . * .* : : : . *:. . ** : . . * . : . * *. . :.: :. . : :* :. .. * *: : ::. *: . . . : * :: .* .* : ** *:: **.*** ***.: : *: ** : *.::.*:: **. ", "identical_positions": 71, "similar_positions": 115, "identity": "10.99%" }, { "cls_id": "homologset.agr.MGI:1860292", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9WUP1-1", "uniprot_id": "RAMP3_MOUSE", "id": "Q9WUP1-1", "name": "Receptor activity-modifying protein 3", "aln": "MKTPAQR-LHLLPLLLLLCGECAQVCGCNETGMLERLPRCGKAFADMMQKVAVWKWCNLSEFIVYYESFTNCTEMETNIMGCYWPNPLAQSFITGIHRQFFSNCTVDRTHWEDPPDEVLIPLIAVPVVLTVAMAGLVVWRSKHTDRLL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9JJ73-1", "uniprot_id": "RAMP3_RAT", "id": "Q9JJ73-1", "name": "Receptor activity-modifying protein 3", "aln": "MATPAQR-LHLLPLLLLLCGECAQVCGCNETGMLERLPRCGKAFAEMMQKVDVWKWCNLSEFIVYYESFTNCTEMETNIVGCYWPNPLAQSFITGIHRQFFSNCTVDRTHWEDPPDEVLIPLIAVPVLLTVAMAGLVVWRSKRTDRLL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O60896-1", "uniprot_id": "RAMP3_HUMAN", "id": "O60896-1", "name": "Receptor activity-modifying protein 3", "aln": "METGALRRPQLLPLLLLLCGGCPRAGGCNETGMLERLPLCGKAFADMMGKVDVWKWCNLSEFIVYYESFTNCTEMEANVVGCYWPNPLAQGFITGIHRQFFSNCTVDRVHLEDPPDEVLIPLIVIPVVLTVAMAGLVVWRSKRTDTLL", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* * * * :********** *.:. ************ ******:** ** ************************:*::**********.*****************.* ************.:**:**************:** **", "identical_positions": 122, "similar_positions": 14, "identity": "82.43%" }, { "cls_id": "homologset.agr.MGI:1860295", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q5RJT2-1", "uniprot_id": "SPB1_RAT", "id": "Q5RJT2-1", "name": "pre-rRNA 2'-O-ribose RNA methyltransferase FTSJ3", "aln": "MGKKGKVG-KSRRDKFYHLAKETGYRSRSAFKLIQLNRRF-QFLQKARALLDLCAAPGGWLQVAAKFMPVSSLIVGVDLVPIKPLPNVVTLQEDITTERCRQALRKELKTWKVDVVLNDGAPNVGASWVHDAYSQAHLTLMALRLACDFLARGGCFITKVFRSRDYQPLLWIFQQLFHRVQATKPQASRHESAEIFVVCQGFLAPDKVDAKFFDPKFAFKEVEVQAKTVTELVT---KKKPKAEGYAEGDLTLYHRTSVTDFLRAANPVDFLSKASEISIDD-----KELAQHPATTEDIRACCQDIKVLGRKELRSLLNWRTKLRRYVAKKLKEQAKALDISLSSEEE--GDEEESAA-ETKQASEEEEEREEEEQLNRTLAEMKAQEVAELKRKKKKLLREQRKQRERVELKMDLPG-VSIADE--GETGMFSLRTIRGQQLLEEVT--QGDMNAADTFLSD----LPRDDIYVSDAEDD-DDTSLESDLDPEELAGVRTHSD----QKEQKSLQFAQVDDSKE--------EEGE-NPLLVP--LEEKAVLQEEQASLWFSKDGFSG--IDDDADEALEISQAQLLYKSRQKEQQPTD----PPPPPTNLKTEKKSSQCQNEVPKETEAIT------DTGGEDR-DSSDSDSS-SSEDEDDWKVSRGKKRSRGSK--ADEDGFEVVPIEDP-VKYRILDPEGLALGAVIASSKKAKRDLIDNSFNRYAFNEEEEELPEWFVQEEKQHRIRQLPLDKKEVEHYRKRWREINARPIKKVAEAKARKKRRMLKKLEQTKKKAEAVVNTVDISEREKVAQLRSLYKKAGLGKEKR-QVTYVVAKKG-VGRKVRRPAGVRGHFKVVDSRMKKDQRAQ-RKEQKRNHRRK----------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9DBE9-1", "uniprot_id": "SPB1_MOUSE", "id": "Q9DBE9-1", "name": "pre-rRNA 2'-O-ribose RNA methyltransferase FTSJ3", "aln": "MGKKGKVG-KSRRDKFYHLAKETGYRSRSAFKLIQLNRRF-QFLQKARALLDLCAAPGGWLQVAAKFMPVSSLIVGVDLVPIKPLPNVVTLQEDITTERCRQALRKELKTWKVDVVLNDGAPNVGASWVHDAYSQAHLTLMALRLACDFLARGGCFITKVFRSRDYQPLLWIFQQLFHRVQATKPQASRHESAEIFVVCQGFLAPDKVDAKFFDPKFAFKEVEVQAKTVTELVT---KKKPKAEGYAEGDLTLYHRTSVTDFLRAANPVDFLSKASEISIDD-----EELAQHPATTEDIRVCCQDIKVLGRKELRSLLNWRTKLRRYVAKKLKEQAKALDISLSSEEEEEGDEEEAVA-ETKQAPEEEEEREEE-QLNRTLAEMKAQEVAELKRKKKKLLREQRKQRERVELKMDLPG-VSIADE--GETGMFSLRTIRGQQLLEEVT--QGDMNAADTFLSD----LPRDDIYVSDAEDD-DDTSLESDLDPEELAGVRTHSD----LKEQKYLRFTQVDDNKE--------EEGE-NPLLVP--LEEKAVLQEEQASLWFSKDGFSG--IEDDADEALEISQAQLLYKSRQKEQQPTD----PPPPPTNLKTEKKSPQGQNEVPKETEAILGTEAVTDPGGEERGNSSDSDSS-SSEDEDSWKVSRGVKRGRGSK--ADEDGFEVVPIQDP-VKYRILDPEGLALGAVIASSKKAKRDLIDNSFNRYAFNEEEGELPEWFAQEEKQHRIRQLPVDKKEVEHYRKRWREINARPIKKVAEAKARKKRRVLKKLEQTKKKAEAVVNTVDISEREKVAQLRSLYKKAGLGKEKR-QVTYVVAKKG-VGRKVRRPAGVKGHFKVVDSRMKKDQRAQQRKEQKKKHKRK----------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8IY81-1", "uniprot_id": "SPB1_HUMAN", "id": "Q8IY81-1", "name": "pre-rRNA 2'-O-ribose RNA methyltransferase FTSJ3", "aln": "MGKKGKVG-KSRRDKFYHLAKETGYRSRSAFKLIQLNRRF-QFLQKARALLDLCAAPGGWLQVAAKFMPVSSLIVGVDLVPIKPLPNVVTLQQDITTERCRQALRKELKTWKVDVVLNDGAPNVGASWVHDAYSQAHLTLMALRLACDFLARGGSFITKVFRSRDYQPLLWIFQQLFRRVQATKPQASRHESAEIFVVCQGFLAPDKVDSKFFDPKFAFKEVEVQAKTVTELVT---KKKPKAEGYAEGDLTLYHRTSVTDFLRAANPVDFLSKASEIMVDD-----EELAQHPATTEDIRVCCQDIRVLGRKELRSLLNWRTKLRRYVAKKLKEQAKALDISLSSGEEDEGDEEDSTAGTTKQPSKEEEEEEEEEQLNQTLAEMKAQEVAELKRKKKKLLREQRKQRERVELKMDLPG-VSIADE--GETGMFSLSTIRGHQLLEEVT--QGDMSAADTFLSD----LPRDDIYVSDVEDDGDDTSLDSDLDPEELAGVRGHQG----LRDQKRMRLTEVQDDKE--------EEEEENPLLVP--LEEKAVLQEEQANLWFSKGSFAG--IEDDADEALEISQAQLLFENRRKGRQQQQKQQLPQTPPSCLKTEIMSPLYQDEAPKGTEASSGTEAATGLEGEEKDGISDSDSSTSSEEEESWEPLRGKKRSRGPK--SDDDGFEIVPIEDP-AKHRILDPEGLALGAVIASSKKAKRDLIDNSFNRYTFNEDEGELPEWFVQEEKQHRIRQLPVGKKEVEHYRKRWREINARPIKKVAEAKARKKRRMLKRLEQTRKKAEAVVNTVDISEREKVAQLRSLYKKAGLGKEKR-HVTYVVAKKG-VGRKVRRPAGVRGHFKVVDSRMKKDQRAQQRKEQKKKHKRK----------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AC58IDS8-1", "uniprot_id": "A0AC58IDS8_DANRE", "id": "A0AC58IDS8-1", "name": "pre-rRNA processing protein FTSJ3", "aln": "MGKKLKVG-KTRKDKFYHLAKETGYRSRSSFKLIQLNRKF-QFLQKARALVDLCAAPGGWLQVASKFMPVSSLVIGVDLVPIKPIPNVVTLQEDITTEKCRQALRKELQTWKVDVVLNDGAPNVGANWQHDAFSQANLTLMALKLACEFLAKGGTFITKVFRSKDYQPLMWIFQQFFKKVQATKPQASRNESAEIFVVCQGFLAPDKIDNKFFDPKHAFKEVDVQVKTVKELVN---KKKPKAEGYSDGDLTLYHKFTITEFLKAENPVDFLSKANEITFDD-----PLLESHPLTSAEIRECCSDVKVLGRKELRLLLSWRSKLRKFLAKKLRQEAKQLDQEASSDDEQSDTDEKESK--KKKSEEKKEEEDEDEAMEKKLTELKAEEFAELKRKKKKLLKERRKQRERVELKMDLPG-VSIADA--GDSSMFSLGSIRKSQGLHQLA--QGDMSAADALLED----DEQEDVHLSDEEQEDERMSLASDLDSDDLQEIQQKEEQMLKNKPKKKKKVSFEQQDDG--------DEDNKNELLVE--LEGKDERKERETSMWFSKDIFAELDLNDDTDAMNELKQTQILQTGRGKKRKAQQ----------EEEAEPKKPEQKVATP----------------SQEVKEAEDSDSDDSSDDEREIAQMKQASAAVGTNGAEENDNIQVIPVEKTNKRARVLDAEGLALGAQIATSKKRERDLIDGSFHRFANSEDMTEVPAWFVDDEKKHRKRPVPVTKDMVEEYKQKWKEINARPIRRVAEAKARKKRRTLKKMEQAKKKAEAVVNTVDISEREKMAQLKSIYKKAGVGKEKR-EVTYVVAKKG-VGRRVRRPAGVKGAFKVVDGRMKKDTRAAQRKDERGRGKGGRGSKGMKGGRGPKGGRGMKAGKGRPNKK", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VXK5-1", "uniprot_id": "Q9VXK5_DROME", "id": "Q9VXK5-1", "name": "Putative rRNA methyltransferase", "aln": "MGKKTKVG-KTRKDKFYQLAKETGLRSRAAFKLIQLNRKF-GFLQQSQVCLDLCAAPGGWMQVAKQNMPVSSIVIGVDLFPIRPIAGCIGLVEDITTEKCRQSLTKELQSWKADVVLHDGAPNVGRNWLYDAYQQICLTLNALKLSTQFLRNGGWFVTKVFRSKDYNALLWVLKQLFKKVHATKPSASRKESAEIFVVCQGYLAPDHIDPRLLDSKYVFEELDLDAKKKSSLLHPEKQKRIKAEGYTAQDIALRNDLAATEFLKAENALAALQGIGSIRIDD-----QRIANHKKTTPEILECCKDLKVLGRKDIKGLVQWWKDVR----ELFVEKETPLVVGNAADEK------------PKPLTQAEIEDMEDAELQTQIETIVEEEKKDLKRKRKKTLKTKAKLHEKMNLNMVIKGDDGPVEE--MEHEIFDLKNIRTSAELDELLDVQPDFAVDESQPEETK--LPKYKYFDKDEGNINDDLNYDDDNDEEQSEASDDEDQ----INDKQGLGLSDDDNDEGNAKGKNKRKKRSENPLIKSNDFRDKNTKREQRVQLWYEKDVLQN-IQSDDDEETYDLNNLAKEFKAKGVAVLGES----------TLTPDANEEVVQGKKAKRR-------------ARHETATKDSSSESSESEDDANEDSDGEQPAAGTN-----------------AKKVRLSENEMALGALLTRSKKTRRDLIDAAWNRYAFNDE--NVPVWFKLDEDEHMTKPTPVPKELTAEYQRKLQEVNVRPIKKVMEAKARKHRRATKRLAKAKKMAEKIMENSDATNHEKSKQLKKVYKKA--QEKKK-EVTYVVAKKQTAARRARRPAGVKGRYKVVDPREKKDKRSMDAKKRREKGSKGRKGKGRK---------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P25582-1", "uniprot_id": "SPB1_YEAST", "id": "P25582-1", "name": "27S pre-rRNA (guanosine(2922)-2'-O)-methyltransferase", "aln": "MGKTQKKNSKGRLDRYYYLAKEKGYRARSSFKIIQINEKYGHFLEKSKVVIDLCAAPGSWCQVASKLCPVNSLIIGVDIVPMKPMPNVITFQSDITTEDCRSKLRGYMKTWKADTVLHDGAPNVGLGWVQDAFTQSQLTLQALKLAVENLVVNGTFVTKIFRSKDYNKLIWVFQQLFEKVEATKPPASRNVSAEIFVVCKGFKAPKRLDPRLLDPKEVFEELPDGQQNMESKIYNPEKKVRKRQGYEEGDNLLYHETSILDFVRTEDPISMLGEMNKFTIDENDHEWKILKKLKQTTDEFRSCIEDLKVLGKKDFKMILRWRKIAR-----------EILGIEVKDDAK---------------TEIEVVPLTEEEQIEKDLQGLQEKQRLNVKRERRRKNEMKQKELQRMQMNMITPTDIGIEAASLGKESLFNLKTAEKTGILNDLAKGKKRMIFTDDELAKDNDIYIDENIMIKDKDSAADADDLESELNAMYSDYKTRRSERDAKFRAKQARGGDNEEEWTGFNEGSLEKKEEEGKDYIEDNDDEGVEGDSDDDEAITNLISKLKGQEGDHKLSSKARMIFNDPIFNNVEPDLPVNTVN------DGIMSSESVGDISKLNKKRKHEEMH----------QKQDEADSSDESSSDDSDFEIVANDNASEEFDSDYDSEEEKNQTKKEKHS-RDIDIATVEAMTLAHQLALGQKNKHDLVDEGFNRYTFRDT-ENLPDWFLEDEKEHSKINKPITKEAAMAIKEKIKAMNARPIKKVAEAKARKRMRAVARLEKIKKKAGLINDDSDKTEKDKAEEISRLMRKVTKKPKTKPKVTLVVASGR-NKGLAGRPKGVKGKYKMVDGVMKNEQRALRRIAKKHHKKK-----------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "***. * . * * *::* ****.* *:*::**:**:*.:: **::::. :*******.* *** : **.*:::***:.*::*:.. : : .***** **. * :::**.*.**:******* .* **: * *** **:*: : * .* *:**:***:**: *:*:::*:*.:*.**** ***: ********:*: **.::* :::*.* .*:*: :. . : :* * :** * * : : :*::: :.: * ..: .*: : . *: :: * .*::***:*::: :: * . * * : *: :: : : :: ::**:::: . : * ::::::* . . :*.* . . *.:: : : : . . .* . : . .: : .. . :: :: .: . : : . : : . : ... . : .: : .. ..*... *...: . ... : ::*. :: .:* .:**:* .::*:: : ::* ** :*.:* *: *. . :.: : :*.***::* ******: * :: : :* * : : * ::::* :: : :*. :.: .** ***. . ** **:* :*:** *:: *: .: . ", "identical_positions": 184, "similar_positions": 255, "identity": "20.11%" }, { "cls_id": "homologset.agr.MGI:1860297", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O35430-1", "uniprot_id": "APBA1_RAT", "id": "O35430-1", "name": "Amyloid-beta A4 precursor protein-binding family A member 1", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MNHLEG----------------------SAEVEVADEAPGGEVNES---------------------------------------------------------------------------VEADLEHPEVEE-------------------------------------------------------------------------------------------------------------EQQPSP--PPPAGHAPEDHRAHPAP-------------------------------------------------------------------------------------------------------------------------------------------------PPP--------------PPPQEEEEE-RGECLARSASTESG--------------------------------------------------------------------FHN---HTDTAEGDVLAAARDGYEAERAQDADDES-------------------------------------------AYAVQYRPEAEEYTEQAE-----------------AEHAEAAQRRALPNH------------LHFHSLEHEEAMNAAYS-------GYVYTHRLFHR------------------------AEDEPYAEPYADYGGLQEHVYEEIG----DAPELEARDGLRLYERERD---EAAAYR-QEALGARLHHYDE-----------------------------RSDGESDSPEKEAEFAPYPRMDS---------------------------YEQEEDIDQIVAEVKQSMS--SQSLDKAAEDMP-EAEQD--------LERAPTPGGGHPDSPG-----------------------------LPAPAGQQQRVVGTPGGSEVGQRY--------------------------------------------------------------------------SKEKRDAISLAIKDIKEAIEEVKTRTIRSPYTPDEPKEPIWVMRQDISPTRDCDDQRPVDGDSPSPGSSS-------------PLGAESSITPLHP---GDPTEAST-------------------------------------------NKESRKSLASFPTYVEVPGPCDPED-----------------------------------------------------------------------------------------------------LIDGIIFAANYLGSTQLLSDKTPSKNVRMMQAQEAVSRIKTAQKLAKSR-KKAPEGESQPMTEVDLFISTQRIKVLNADTQEPMMDHPLRTISYIADIGNIVVLMARRRMPRSNSQEN------VEASHPS------------QDAKRQYKMICHVFESEDAQLIAQSIGQAFSVAYQEFLRANGINPEDLS-QKEYSDLLNTQDMYNDDLIHFSKSENCKDVFIEKQKGEILGVVIVESGWGSILPTVIIANMMHGGPAEKSGKLNIGDQIMSINGTSLVGLPLSTCQSIIKGLKNQSRVKLNIVRCPPVTTVLIRRPDLRYQLGFSVQNGIICSLMRGGIAERGGVRVGHRIIEINGQSVVATPHEKIVHILSNAVGEIHMKTMPAAMYRLLTAQEQPVYI", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "B2RUJ5-1", "uniprot_id": "APBA1_MOUSE", "id": "B2RUJ5-1", "name": "Amyloid-beta A4 precursor protein-binding family A member 1", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MNHLEG----------------------SAEVEVADEAPGGEVNES---------------------------------------------------------------------------VEADLEHPEVVE-------------------------------------------------------------------------------------------------------------GQQPSPSPPPPAGHEPEDHRGHPAP-------------------------------------------------------------------------------------------------------------------------------------------------PPP--------------PPPQEEEEEERGECLARSASTESG--------------------------------------------------------------------FHN---HTDTAEGDVLAAARDGYEAERAQDADDES-------------------------------------------AYAVQYRPEAEEYTEQAE-----------------AEHVEAAQRRALPNH------------LHFHSLEHEEAMNAAYS-------GYVYTHRLFHR------------------------AEDEPYAEPYADYGGLQEHVYEEIG----DAPELEARDGLRLYERERD---EAAAYR-QEALGARLHHYDE-----------------------------RSDGESDSPEKEAEFAPYPRMDS---------------------------YEQEEDIDQIVAEVKQSMS--SQSLDKAAEDMP-EAEQD--------LERAPTPGGGHPDSPG-----------------------------LPAPAGQQQRVVGTPGGSEVGQRY--------------------------------------------------------------------------SKEKRDAISLAIKDIKEAIEEVKTRTIRSPYTPDEPKEPIWVMRQDISPTRDCDDQRPVDGDSPSPGSSS-------------PLGAESSSIPLHP---GDPTEAST-------------------------------------------NKESRKSLASFPTYVEVPGPCDPED-----------------------------------------------------------------------------------------------------LIDGIIFAANYLGSTQLLSDKTPSKNVRMMQAQEAVSRIKTAQKLAKSR-KKAPEGESQPMTEVDLFISTQRIKVLNADTQEPMMDHPLRTISYIADIGNIVVLMARRRMPRSNSQEN------VEASHPS------------QDGKRQYKMICHVFESEDAQLIAQSIGQAFSVAYQEFLRANGINPEDLS-QKEYSDLLNTQDMYNDDLIHFSKSENCKDVFIEKQKGEILGVVIVESGWGSILPTVIIANMMHGGPAEKSGKLNIGDQIMSINGTSLVGLPLSTCQSIIKGLKNQSRVKLNIVRCPPVTTVLIRRPDLRYQLGFSVQNGIICSLMRGGIAERGGVRVGHRIIEINGQSVVATPHEKIVHILSNAVGEIHMKTMPAAMYRLLTAQEQPVYI", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q02410-1", "uniprot_id": "APBA1_HUMAN", "id": "Q02410-1", "name": "Amyloid-beta A4 precursor protein-binding family A member 1", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MNHLEG----------------------SAEVEVTDEAAGGEVNES---------------------------------------------------------------------------VEADLEHPEVEE-------------------------------------------------------------------------------------------------------------EQQQPP----QQQHYVGRHQRGRAL-------------------------------------------------------------------------------------------------------------------------------------------------EDL--------------RAQLGQEEEERGECLARSASTESG--------------------------------------------------------------------FHN---HTDTAEGDVIAAARDGYDAERAQDPEDES-------------------------------------------AYAVQYRPEAEEYTEQAE-----------------AEHAEATHRRALPNH------------LHFHSLEHEEAMNAAYS-------GYVYTHRLFHR------------------------GEDEPYSEPYADYGGLQEHVYEEIG----DAPELDARDGLRLYEQERD---EAAAYR-QEALGARLHHYDE-----------------------------RSDGESDSPEKEAEFAPYPRMDS---------------------------YEQEEDIDQIVAEVKQSMS--SQSLDKAAEDMP-EAEQD--------LERPPTPAGGRPDSPG-----------------------------LQAPAGQQ-RAVGPAGGGEAGQRY--------------------------------------------------------------------------SKEKRDAISLAIKDIKEAIEEVKTRTIRSPYTPDEPKEPIWVMRQDISPTRDCDDQRPMDGDSPSPGSSS-------------PLGAESSSTSLHP---SDPVEAST-------------------------------------------NKESRKSLASFPTYVEVPGPCDPED-----------------------------------------------------------------------------------------------------LIDGIIFAANYLGSTQLLSDKTPSKNVRMMQAQEAVSRIKMAQKLAKSR-KKAPEGESQPMTEVDLFISTQRIKVLNADTQETMMDHPLRTISYIADIGNIVVLMARRRMPRSNSQEN------VEASHPS------------QDGKRQYKMICHVFESEDAQLIAQSIGQAFSVAYQEFLRANGINPEDLS-QKEYSDLLNTQDMYNDDLIHFSKSENCKDVFIEKQKGEILGVVIVESGWGSILPTVIIANMMHGGPAEKSGKLNIGDQIMSINGTSLVGLPLSTCQSIIKGLKNQSRVKLNIVRCPPVTTVLIRRPDLRYQLGFSVQNGIICSLMRGGIAERGGVRVGHRIIEINGQSVVATPHEKIVHILSNAVGEIHMKTMPAAMYRLLTAQEQPVYI", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1Q7S5-1", "uniprot_id": "A0A8M1Q7S5_DANRE", "id": "A0A8M1Q7S5-1", "name": "", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSHQEAPHG--------------QELREAAEADLERRGPEGQQPPSSHRRRHNNGDGSSRSNRSRNHGTEN-----------------NHHQSQHQGAPRYRRCEGSNGGTNRTHAARRPEEEGDAEQQTIQQPIPRPA----------------------------------------------------------------------------------------VTRYRRQGDNEARLRAQQQRQRQRERQQRDAERAEQHRLE-------------------------------------------------------------------------------------------------------------------------------------------------QQQQLLSPTQTMLPTREPEEAEEDEGDGSSALARSASTESG--------------------------------------------------------------------FHN---HTDRAEGDAVMVL----EAE----PEDEN-------------------------------------------TYGIPLRPEAEEYTESAE-----------------SEQQHGGPAYLQPQYPPQPPPLPREPLPNAERPLEAETLNPNYS-------SYVYTQPMYHNPTEA------------GEAHEGGATEDEQYSEPYVDYT-LQEHVYEEIT----DAPLSRAEGQTPQQQRPEFRLFERDLYQQQEAVGSRLHHYDE-----------------------------RSDGESDSPEKEAEFAPYPRADS---------------------------CEQDEDIDQIVAEVKESLS--SQSLDRIAMGLNKDGDKE--------EDWPESESHGQLNDNN-----------------------------PLEPVSEGELPRSPSEDQAPVIRS--------------------------------------------------------------------------SREKRDAISLAIKDIKEAIEEVKTRTVRSPYTPDEPKEPIWVMRQDLSPTAESDLQPSLGADSPGSGSTS-------------PQGAESSSHQMMSQEGSDSFESPSPA-----------------------------------------GKESRRSLASFPTYVEVPGPCDPED-----------------------------------------------------------------------------------------------------LIDGIIFAANYLGSTQLLSDKTPSKNVRMMQAQEAVSRIKTAQKLAKNK-KKAPEGDAQPMTEVDLFISTQRIKVLNADSQETMMDHPLRTISYIADIGNIVVLMARRRMPRSDSQEN------MEASDPA------------QDEKRQYKMICHVFESEDAQLIAQSIGQAFSVAYQEFLRANGINPEDLS-QKEYSDLLNTQDMYNDDLIHFSKSENCKDVYIEKQKGEILGLVIVESGWGSILPTVIIANMMHGGPAEKSGRLNIGDQIMSINGTSLVGLPLSTCQSIIKGLKNQSRIKLNIVRCPPVTTVLIRRPDLRYQLGFSVQNGIICSLMRGGIAERGGVRVGHRIIEINSQSVVATPHEKIVHILSNAVGEIHMKTMPAAMYRLLTAQEQPVYI", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "E7FGL9-1", "uniprot_id": "E7FGL9_DANRE", "id": "E7FGL9-1", "name": "", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSHREE----------------------PEEAGLRGPPPHRSKQPNG----------------------------------------------------------------TPLEGGRPRWRPCQLHNPDAES------------------------------------------------------------------------------------------------------------QGQHHHHYHHQAHQHASGSSRAPPRH-------------------------------------------------------------------------------------------------------------------------------------------------RRRHVPGQAQRRRPESGDSEARAGQQPKPGASKHHRSGERL--------------------------------------------------------------------YQHRYRQQHKDEEQHVKTPPKEQASEPLLSPDDSS-------------------------------------------QDLLTPSPQDEPVTDELDESSPDLSHSSDTQINRDPEQEQAESSVDQPEENVHREEFKNPCEEELVKVNEVEDLSTQIP-------EEDYVPPKIASKSR---------------------PESKRTSPLRVDVPPFATSPHQIINKPFFQSPRSFPESLRRYNSDPKS---YPTFFNNNYACTRNDKEFDSP----------------------------RSHDEGDLSDSEAYTDSYPESHP---------------------------KDTETDLNPAFEEPQAYEMNYSMSMDECDDQQDLEEEPNPHSAVGSRLHHYDEQSGDEAESFGRSRAHLRKTSSSTSLPLEVHPQDDETSEMTQNSTDLQEEVEDVPEKQDQITES--------------------------------------------------------------------------CKATGDAVSLAIRDIKEAIEEVKTKTVRSPYMPDKITEPVWVMRQDVSPVEESHPQIHSYPQSPCQISQSSPQYAAPIQDAEPPLGAESSGVLHQD---QDQELCPNVP-----------------------------------------SEEQRKSLASFPTYVDVPGPCDPED-----------------------------------------------------------------------------------------------------LIDGIIFAANYLGSTQLLSERTPTKSARMQQAQEAMSRVRTAQAQAKIRNKQGTESGPPSCTEVDLFISTQRIKVLSAYTQDTMMDHPLRTISYIADIGNMVVLMARRKMIRSQSAQENLDTAETQHTNPA------------RDDRRQYKMICHVFESEDAQLIAQSIGQAFSVAYQEFLRANGIDPEDLS-QREYSDLLNTQDMYNDDLIHFSKSENCRDVYIEKQKGEILGVVIVESGWGSILPTVIIASLMHGGPAAKSGRLNIGDQIMTVNGTSLVGLPLSTCQSIIKGLKSQSRIKMNIVRCPPVTMVLIRRPDLRYQLGFSVQNGIICSLMRGGIAERGGVRVGHRIIEINGQSVVATPHEKIVHILSNAVGEIHMKTMPAAMYRLLTAQEQPVYI", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "X2JE74-1", "uniprot_id": "X2JE74_DROME", "id": "X2JE74-1", "name": "", "aln": "--------------------------------------------------------------------MNSNSCSDSSNE---------------------SMVNPP-----HIQMNFG-----QQAQQQQSHQHQQQQQQQ--------ERYVWEMRTRS-----------------------------PNVTPASTVLN------------SPDLNGELSYVPLQGLSP---------------------------------------------------------------------------------SGGGVQGSGSYGSNAGRDS----------------------------------------------------------------------------------GSYYYQR-------------PQLHQIRLGRSPGS-----------------------QFETRDVLPQGLASP--------------GSPTDVGKADG----------------------------------------QCLRDGEIVVFDDIDTNWMNKASSGQR---------------------------------PGSNEDVLKVT----------------KMIGQLP------------------------------------IAEYEGSPRRFGSQPNTNTITMGGPRK-----------------------RP------------------------------------------------------------------------PGFPQRVSP------------------------------------TTSVANN----------------ATAAAKASVGNLIDLVDHEEE-------------------------------------RSG------------------TLREKTPTFDYLYEFSETRKVLEEFFKANPEDEKRYTDYTTESG----------------DDVASSQPQE-----------------YPATPMEQAYIGQRLARIPK-----DELYMVHR----SPTKKPPSDQNPSTAYQEHN-------DIELYIDSNSRSSGD-------LADTELEANLRRHS----------------RNFTLSPETTDYDSNCGDLDSLSNDIN-----CPTDFGKLYTS-MPVLEDGLSSGHASDTENNVSVVCDKQQSSQSQP---------VHEHNGNG--------ERLENDYNVMSAS----LATLTTDAS------QSALISDFASLPMP-------PAPPPSSPPQIEIADASES--MTMVPDADNPLDSHYGA----------VYAAALGGTHTEKSAGSGLGVTPVTAGG-----SLPS--------QAASEIQEAMKEIRSALQRAKTQ----------------------------------PEKLKFCDEVLPTD---PDSPVWVPR------------KGTTISTAQGAAADEEPDTDLETDRLLGQQRHDEQDFFADQSLADNN-ANEGTDIASNGHLNGTSDNNNPNPMNNSKPQTYSTATIR--QGIGTSLTP---NSPDICQIVG-------------------------------------------TTDISISSPEKLQFTKSPTGSIKSLKDSAN-------------------------------------------------------------------SDKKAKSRNKEGLLEPK---------VLIEGVLFRARYLGSTQLVCEGQPTKSTRMMQAEEAVSRIK----------ALAPEGESQPSTEVDLFISTEKIMVLNTDLKEIMMDHALRTISYIADIGDLVVLMARRRFVPNSVVDPSITSPLGDVPTPGIGEEESPPKEPLSKHNRTPKMICHVFESDEAQFIAQSIGQAFQVAYMEFLKANGIENESLAKEMDYQEVLNSQEIFGDELEIFAKKELQKEVVVPKAKGEILGVVIVESGWGSMLPTVVIANLMSSGAAARCGQLNIGDQLIAINGMSLVGLPLSTCQSYIRNAKNQTAVKFTVVPCPPVVEVKILRPKALFQLGFSVQNGVICSLLRGGIAERGGVRVGHRIIEINNQSVVAVPHDTIVKLLSSSVGEILMKTMPTSMFRLLTGQETPIYI", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9W2S5-1", "uniprot_id": "Q9W2S5_DROME", "id": "Q9W2S5-1", "name": "", "aln": "MVSTTLTTLAAGQTTSSSNHHHHHHHSHQQQQQQQQQDQSQQQPHQQLPYQQRGYYALNGSLELDCDTSNTNSSSSSNNIGYQQHQQQQQQQQQPPLILSQALLSPSPPLNDQISLLFPKCRPKQQQQQQQQQQQQQQQQQQQLQPAQQHQQHVHPTDVNSSCNSNRSSSPTTAGAVGEPLASVSVSPPPPKATPTSSTPSYYKSVNIITQSPPPHSASSHSSESLSSVTPRISTNPFLCAPLTPPTPPHHHHHHHHQQQHQQKQQQPKQQHQTQQQEQQEEDTTGESVVEHSRSGAAGEVLEYPASFYYHTVGDSRRGPGSYTEMPRKRSSALPASNRQQQLHNGNGSQNPFIKENYWEAPPTRASLLLHSPTEYSEEPQQQQQIQQQQQQQQQQQQQQQQQQQQHLHASARRAYHQQREQVYGINQRPQQQQQQNILRVGRSPVNRSFPQQHQQQQQQQQQQQQQQQQQQQPHQQIPTARSNPCADGLTPLASHYLYGSKSSLDQHPGDWEPREQRKLRLREEREREREREREREREREREHLLLEQQQQLQLQEVQVARDNHLSHLAGQQQQQQQRKRHVYGEERERERDRERDMDRDHRLVNGNADPNESWQHLRVTTETLAEEGGKHGKPADKAQHQMHNTNQSQNSDVNVYREHQLDAWKLERSYTLAVESRHGIIEYEGSPRRIGVTTTSNLGATGAAAASAAADESEPPAAAEGAAAATATSQPQQQVPMATVPPLSSTATSLQKTAARAALAALAQSHPHSSHNILSTLLPHSPNPVNPGQMHAAQQSIQNYPVRPGFPQRIISPPSRDPRSSSPPLQQQQYQQQQQQQLQHQQQHFASLMSSHSNNNSNTNKQPLSSDNNAEDTSNDVSEIGTISDLTTPEAVGLSIGIAAGEMASRASTPPQTAQAPPTAVAGSTANGTGSGNGTATGNATAAGSGLGPLSLHTKSSTFDYLYEFSETRKVLEEFFKCPSTDEQPIMENGSDVDSIDIQYEFHSNFERDEEDLAEEEEAEDDEEVDDDADEENDEAEDEDEPLEQDRDQNYRAQAPPQSGHIDSERLVYSGYGQQPQLQAQLTAQPMSGARRHYSGSPLMRDFDFFLDSTSRSSGERDADQDGLNHNQLLSTSSGHGGGVGVSGGLGVGPGGGHNYRYSPETTDYDSNCGDLDSLSGEMNGGVSTSCSNYAKFYASAMPVLEDGLSSGHTSDTENNNNNQKNLQQSTVNQGGQCPTSLSGSTSIGGSGGISMLMDMKRISTNHSLNSMNNQTTTASTTTDSNGGVGGVGHHLVATLVASPNNEQAKSQCQTQLQSHPPKTLSLDQSPSNHSKVFKNIDPELDSLYSIGVFHRPDTVQMTPPPPAPAPHRKPNNNGCSSGVVNTNG-----SLAGGSNDVDLLQPSSKHTPLAAAISSTLQRSSPTSTITGNGIGNGSGKTRSAGSNCSSSANGGMPPPIPERTNLVSAVQRSPSPGPNSPVWLSRHLDGGAGKDLLESGSDNHSKNHSADEEDVDTDLETDRLLGHQRLDDQGYYDENKSWDRKPRSLLSKISPKQQIPSTKTRNGYNALLSSTPELPPPIPPKGQSGLGLGLTLGAGNGGKLLDLVGGMVQRSLSRSSSEHSEKSLSKMPISGGDLCAGGVDVVASTVAATSATVVASTPALGSPGNGGGSERSAAEMANPGGAVKLSEQEIGTINGGSVMPLGSGSGTGSGAGSGAGSGTGTNAAVVANSNANNNVGGGGGGGNNSSGSGAGSNSNSGEKKVKKSKSKEGGAVLIEGVLFRAKYLGSTQLVCEGQPTKSTRMMQAEEAVSRIK----------ALAPDGDVQPSTEVDLFISTEKIMVLNTDLKEIMMDHALRTISYIADIGDLVVLMARRRFVP---------QDIDDAPKP----------------NRTPKMICHVFESDEAQFIAQSIGQAFQVAYMEFLKANGIEDHRFVKEMDYQEVLNSQEIFGDELEIFAKKELQKEVVVPKAKGEILGVVIVESGWGSMLPTVVIANLMSSGAAARCGQLNIGDQLIAINGLSLVGLPLSTCQTYIKNTKNQTVVKFTVVPCAPVVEVKIKRPETKYQLGFSVQNGVICSLLRGGIAERGGVRVGHRIIEINNQSVVAVPHEKIVNLLATSVGEILMKTMPTSMFRLLTGQENPIYI", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :.: : . . . . * : . : . .: . * . . .. * * : : . . . . . .. .. . . . . . . . . . . : .: . :* : : . : .: . . : . . .. . ::* . .. **:*::* *.*******:.: *:*..** **:**:**:: ..:. . *********::* **.: :: ****.***********::*******:: : . * .* *********::**:*********.*** ***:****: . : : :*.::**:*:::.*:* *:*.* ::* : * ******:*********:****:**.:* .*.* :.*:******::::** ***********: *:. *.*: :*:.:* *.**. * * **. :*********:****:********************.*****.**:.**::*:.:**** *****::*:****.** *:**", "identical_positions": 223, "similar_positions": 164, "identity": "10.23%" }, { "cls_id": "homologset.agr.MGI:1860298", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9WU66-1", "uniprot_id": "SFRP5_MOUSE", "id": "Q9WU66-1", "name": "Secreted frizzled-related protein 5", "aln": "MWVAWS---ARTAALALLLGALHGAPTRGQEYDYYGWQAEPLHGRSYSKPPQCLDIPADLPLCHTVGYKRMRLPNLLEHESLAEVKQQASSWLPLLAKRCHSDTQVFLCSLFAPVCLDRPIYPCRSLCEAARAGCAPLMEAYGFPWPEMLHCHKFPLDNDLCIAVQFGHLPATAPPVTKICAQCEMEHSADGLMEQMCSSDFVVKMRIKEIKIDNGDRKLIGAQKKKKLLKAGPLKRKDTKKLVLHMKNGASCPCPQLDNLTGSFLVMGRKVEGQLLLTAVYRWDKKNKEMKFAVKFMFSYPCSLYYPFFYGAAEPH", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D3ZTV6-1", "uniprot_id": "D3ZTV6_RAT", "id": "D3ZTV6-1", "name": "Secreted frizzled-related protein 5", "aln": "MRVAGG---ARTAALALLLGALHGAPARGQEYDYYGWQTEPLHGRSYSKPPQCLDIPADLPLCHTVGYKRMRLPNLLEHESLAEVKQQASSWLPLLAKRCHSDTQVFLCSLFAPVCLDRPIYPCRSLCEAVRAGCAPLMEAYGFPWPEMLHCHKFPLDNDLCIAVQFGHLPATAPPVTKICAQCEIEHSADGLMEQMCSSDFVVKMRIKEIKIDNGDRKLIGAQKKKKLLKAGPLKRKDTKKLVLHMKNGASCPCPQLDNLTGSFLVMGRKVEGQLLLTAVYRWDKKNKEMKFAVKFMFSYPCSLYYPFFYGAAEPH", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q5T4F7-1", "uniprot_id": "SFRP5_HUMAN", "id": "Q5T4F7-1", "name": "Secreted frizzled-related protein 5", "aln": "MRAAAAGGGVRTAALALLLGALHWAPARCEEYDYYGWQAEPLHGRSYSKPPQCLDIPADLPLCHTVGYKRMRLPNLLEHESLAEVKQQASSWLPLLAKRCHSDTQVFLCSLFAPVCLDRPIYPCRSLCEAVRAGCAPLMEAYGFPWPEMLHCHKFPLDNDLCIAVQFGHLPATAPPVTKICAQCEMEHSADGLMEQMCSSDFVVKMRIKEIKIENGDRKLIGAQKKKKLLKPGPLKRKDTKRLVLHMKNGAGCPCPQLDSLAGSFLVMGRKVDGQLLLMAVYRWDKKNKEMKFAVKFMFSYPCSLYYPFFYGAAEPH", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* .* . .************* **:* :********:*******************************************************************************************.******************************************************:***************************:*****************.*********:*********.*******.*:**********:***** **************************************", "identical_positions": 294, "similar_positions": 15, "identity": "92.74%" }, { "cls_id": "homologset.agr.MGI:1860299", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8IVF4-1", "uniprot_id": "DYH10_HUMAN", "id": "Q8IVF4-1", "name": "Dynein axonemal heavy chain 10", "aln": "-------------------------------------------------------------------------------------MVPEEVEVEI-----------DEIPVLSEEGEEE-------EETYSQKVESVDKVRAKRVSLRTE-----SLG-QPLNREDEEMDKEISEKLPS-------------------------KRTAKHIMEKMHLHMLCTPLPEEFLDQ-------------------NVVFFLRNTKEAISEATDMKEAMEIMPETLEYGIINANVLHFLKNIICQVFLPALSFNQHRTSTT--VGVTSGEVSN------------------------------------------------------------------------------------------------------------SSEHES-DLPPMPGEAVEYHSIQLIRDEFLMNVQKFASNIQRTMQQLEGEIKLEMPIISVEGEVSDLAADPE---------------TVDILEQCVINWLNQISTAVEAQLKKTPQGKGPLAEIEFWRERNATLSALHEQTKLPIVRKVLDVIKESDSMLVANLQPVFTELFKFHTEASDNVRFLSTVERYFKNITHGSGFHVVLDTIPAMMSALRMVWIISRHYNKDERMIPLMERIAWEIAERVCRVVNLRTLFKENRASAQSKTLEARNTLRLWKKAYFDTRAKIEASGREDRWEFDRKRLFERTDYMATICQDLSDVLQILEEFYNIFGPELKAVTGDPKRIDDVLCRVD-GLVTPMENLTFDPFSIKSSQFWKYVMDEFKIEVLID---------------------------------------------------------IINKIFVQNLENPPLYKNHPPVAGAIYWERSLFFRIKHTILRFQEVQE---ILDSDRGQEVKQKYLEVGRTMKEYEDRKYEQWMEVTEQVLPALMKKSLLTKS------------------------------------------------------------SIATEEP---------------------------------------------------------------------------------------------STLERGAVFAINFSPALREIINETKYLEQLGFTVPELARNVALQEDKFLRYTAGIQRMLDHYHMLIGTLNDAESVLLKDHSQELLRVFRSGYKRLNWNSLGIGDYITGCKQAIGKFESLVHQIHKNADDISSRLTLIEAINLF---------------------------------------------KYPAAKSEEELPG-----VKEFFEHIERERASDVDHMVRWYLAIGPLLTKVEGLVVHTNTGKAPKLASYYKYWEKKIYEVLTKLILKNLQSFNSLILGNVPLFHTETILTAPEIILHPNTNEIDKMCFHCVRNCVEITKHFVRWMNGSCIECPPQKGE-EEEVVIINFYNDISLNPQIIEQAVMIPQNVHRILINLMKYLQKWKRYRPLWKLDKAIVMEKFAAKKPPCVAYDEKLQFYSKIAYEVMRHPLIKDEHCIRLQLRHLANTVQENAKSWVISLGKLLNESAKEELYNLHEEMEHLAKNLRKIPNTLEDLKFVLATIAEIRSKSLVMELRYRDVQERYRTMAMYNLFPPDAEKELVDKIESIWSNLFNDSVNVEHALGDIKRTFTELTRGEIMNYRVQIEEFAKRFYSEGPGSVGDDLDKGVELLGVYERELARHEKSRQELANAEKLFDLPITMYPELLKVQKEMSGLRMIYELYEGLKVAKEEWSQTLWINLNVQILQEGIEGFLRALRKLPRPVRGLSVTYYLEAKMKAFKDSIPLLLDLKNEALRDRHWKELMEKTSVFFEMT-ETFTLENMFAMELHKHTDVLNEIVTAAIKEVAIEKAVKEILDTWENMKFTVVKYCKGTQERGYILGSVDEIIQSLDDNTFNLQSISGSRFVGPFLQTVHKWEKTLSLIGEVIEIWMLVQRKWMYLESIFIGGDIRSQLPEEAKKFDNIDKVFKRIMGETLKDPVIKRCCEAPNRLSDLQNVSEGLEKCQKSLNDYLDSKRNAFPRFFFISDDELLSILGSSDPLCVQEHMIKMYDNIASLRFNDGDSGEKLVSAMISAEGEVMEFRKILRAEGRVEDWMTAVLNEMRRTNRLITKEAIFRYCE--DRSRVDWMLLYQGMVVLAASQVWWTWEVEDVFHKAQ-KGEKQAMKNYGRKMHRQIDELVTRITMPLSKNDRKKYNTVLIIDVHARDIVDSFIRGSILEAREFDWESQLRFYWDREPDELNIRQCTGTFGYGYEYMGLNGRLVITPLTDRIYLTLTQALSMYLGGAPAGPAGTGKTETTKDLAKALGLLCVVTNCGEGMDYRAVGKIFSGLAQCGAWGCFDEFNRIDASVLSVISSQIQTIRNALIHQLTTFQFEGQEISLDSRMGIFITMNPGYAGRTELPESVKALFRPVVVIVPDLQQICEIMLFSEGFLEAKTLAKKMTVLYKLAREQLSKQYHYDFGLRALKSVLVMAGELKRGSSDLREDVVLMRALRDMNLPKFVFEDVPLFLGLISDLFPGLDCPRVRYPDFNDAVEQVLEENGYAVLPIQVDKVVQMFETMLTRHTTMVVGPTRGGKSVVINTLCQAQTKLGLTTKLYILNPKAVSVIELYGILDPTTRDWTDGVLSNIFREINKPTDKKERKYILFDGDVDALWVENMNSVMDDNRLLTLANGERIRLQAHCALLFEVGDLQYASPATVSRCGMVYVDPKNLKYRPYWKKWVNQIPNKVEQYNLNSLFEKYVPYLMDVIVEGIVDGRQAEKLKTIVPQTDLNMVTQLAKMLDALLE-------------GEIEDLDLLECYFLEALYCSLGASLLEDGRMKFDEYIKRLASLSTVDTE-GVWANPGELPGQLPTLYDFHFDNKRNQWVPWSKLVPEYIHAPERKFINILVHTVDTTRTTWILEQMVKIKQPVIFVGESGTSKTATTQNFLKNLSEETNIVLMVNFSSRTTSMDIQRNLEANVEKRTKDTYGPPMGKRLLVFMDDMNMPRVDEYGTQQPIALLKLLLEKGYLYDRGKELNCKSIRDLGFIAAMGKAGGGRNEVDPRFISLFSVFNVPFPSEESLHLIYSSILKGHTS--TFHESIVAVSGKLTFCTLALYKNIVQDLPPTPSKFHYIFNLRDLSRVFNGLVLTNPERFQTVAQMVRVWRNECLRVFHDRLISETDKQLVQQHIGSLVVEHFK-----------------------------------------------------DDVEVVMRDPILFGDFQMALHEGEPRIYEDIQDYEAAKALFQEILEEYNESNTKMNLVLFDDALEHLTRVHRIIRMDRGHALLVGVGGSGKQSLSRLAAFTASCEVFEILLSRGYSENSFREDLKSLYLKLGIENKAMIFLFTDAHVAEEGFLELINNMLTSGIVPALFSEEEKESILSQIGQEALKQGMGPAKESVWQYFVNKSANNLHIVLGMSPVGDTLRTWCRNFPGMVNNTGIDWFMPWPPQALHAVAKSFLGYNPMIPAENIENVVKHVVLVHQSVDHYSQQFLQKLRRSNYVTPKNYLDFINTYSKLLDEKTQCNIAQCKRLDGGLDKLKEATIQLDELNQKLAEQKIVLAEKSAACEALLEEIAVNTAVAEEKKKLAEEKAMEIEEQNKVIAMEKAEAETTLAEVMPILEAAKLELQKLDKSDVTEIRSFAKPPKQVQTVCECILIMKGYKELNWKTAKGVMSDPNFLRSLMEIDFDSITQSQVKNIKGLLKTLNTTTEEMEAVSKAGLGMLKFVEAVMGYCDVFREIKPKREKVARLERNFYLTKRELERIQNELAAIQKELETLGAKYEAAILEKQKLQEEAEIMERRLIAADKLISGLGSENIRWLNDLDELMHRRVKLLGDCLLCAAFLSYEGAFTWEFRDEMVNRIWQNDILEREIPLSQPFRLESLLTDDVEISRWGSQGLPPDELSVQNGILTTRASRFPLCIDPQQQALNWIKRKEEKNNLRVASFNDPDFLKQLEMSIKYGTPFLFRDVDEYIDPVIDNVLEKNIKVSQGRQFIILGDKEVDYDSNFRLYLNTKLANPRYSPSVFGKAMVINYTVTLKGLEDQLLSVLVAYERRELEEQREHLIQETSENKNLLKDLEDSLLRELATSTGNMLDNVDLVHTLEETKSKATEVSEKLKLAEKTALDIDRLRDGYRPAARRGAILFFVLSEMALVNSMYQYSLIAFLEVFRLSLKKSLPDSILMKRLRNIMDTLTFSIYNHGCTGLFERHKLLFSFNMTIKIEQAEGRVPQEELDFFLKGNISLEKSKRKKPCAWLSDQGWEDIILLSEMFSDNFGQLPDDVENNQTVWQEWYDLDSLEQFPVPLGYDNNITPFQKLLILRCFRVDRVYRAVTDYVTVTMGEKYVQPPMISFEAIFEQSTPHSPIVFILSPGSDPATDLMKLAERSGFGGNRLKFLAMGQGQEKVALQLLETAVARGQWLMLQNCHLLVKWLKDLEKSLERITKPHPDFRLWLTTDPTKGFPIGILQKSLKVVTEPPNGLKLNMRATYFKISHEMLDQCPHPAFKPLVYVLAFFHAVVQERRKFGKIGWNVYYDFNESDFQVCMEILNTYLTKAFQQRDPRIPWGSLKYLIGEVMYGGRAIDSFDRRILTIYMDEYLGDFIFDTFQPFHFFRNKEVDYKIPVGD--EKEKFVEAIEALPLANTPEVFGLHPNAEIGYYTQAARDMWAHLLELQPQTGESSSGISRDDYIGQVAKEIENKMPKVFDLDQVRKRLGTGLSPTSVVLLQELERFNKLVVRMTKSLAELQRALAGEVGMSNELDDVARSLFIGHIPNIWRRLAPDTLKSLGNWMVYFLRRFSQYMLWVTESEPSVMWLSGLHIPESYLTALVQATCRKNGWPLDRSTLFTQVTKFQDADEVNERAGQGCFVSGLYLEGADWDIEKGCLIKSKPKVLVVDLPILKIIPIEAHRLKLQNTFRTPVYTTSMRRNAMGVGLVFEADLFTTRHISHWVLQGVCLTLNSD-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F7ABZ6-1", "uniprot_id": "F7ABZ6_MOUSE", "id": "F7ABZ6-1", "name": "", "aln": "---------------------MDDLRVLWMRDRVYTAFNLTNPMLFEEMLSRDDSEAEDCILHFLNHLSDEDNASALFF---YRILVPEEVEVEE-----------PDIPLVFDEEGEE-------EESDYQKVEATEKMSVKFSKLRSD-----SMTPSLFDMDDEEPDVETYSKLYG-------------------------KKIVKRIINKLELRVNLASLPEEFLQQ-------------------NVVFFLRSSKDAIPEATDMKEAMEIMPETMEYGVINSQVLQLLKDVICQVFMPALSFNQHKSESG--QGTLSGENQE------------------------------------------------------------------------------------------------------------FSVYDLAESVVIPGEPMEYHSVQLIRDEFLMNLQKFENNIQRTIQQLEGEIKLEMPSISVEGDMSELVSNPE---------------LVENLEQCVIHWLGQISYALDSQMKKKPQGNGPLAEIEFWRERNATLSALYEQTKLPFVRKVLEVIKEAESMLTANVQPILTELFKLHMEASDNVRFLSTVERHFKNITHGSSFHVVLDTIPSMMSALRMVWIISRHYNRDERMIPLMERIAWEIAERVCRVINLRTLFKENRANAQFKTQEARNTLKLWKKSYFDIRAKIEASGREARWEFDRKRLFERTDYMANICQDLSDVLQVLEEFYNIFGPELKAVTGDPKRIDDVLGRVD-SLVAPMESLSFDPFSIRSSPYWKYVMEDFKLEVLID---------------------------------------------------------IVNKIFVQNQDNPPLYKNHPPVAGAICWERSLFYRIKHTILRFMEVEE---LLDSERGQQVKQRYLEVGRKMKEYEDGKYEHWKETTEQSLPTLMKKSLLTKN------------------------------------------------------------IITAEDS---------------------------------------------------------------------------------------------AIIDRGTTFIINFSPVLKEIINETKYLEQLGFTIPELARNVALQEDKFLRYTEGIQRMLDHYHLLINTLNEAETALLDDHSQELLRVFRSGYKRLNWNSLGISDYITRCKQAIGKFETLVHQIHKNADDINSRLTLIESVSLF---------------------------------------------RFPVAKTADGVPG-----VKEFFEYIERERARDVDHMVRWYMAIGPLLTKVEGLVVHTNTGRAPKLASYYEYWEGKIYDVLVKLIQKNLQAFNSLILRNVPLFQAETILSAPEIVLHPNANEIDKMCVHCVRSCVEVTKHFVRWMNGSCIECPPQKGE-EEEVVIISFYNDISQNTQIMDQALMIPQNIHRLLVNIMKYLQRWKRYRPLWKLDKSIVMEKFAAKKPACVAYDEKLQFYSKIATDVMRHPLIKDEHCIRLQLEPLASTVQENAKSWVISLGKLLNESAREELYSLRDEIEHLAKNLKKSPSTLEDLKFVLATISEIRSKSLVMELRYKDIQERYRTMAIYKIFPTDTEQELVNNIENMWESLFTESMNVEHALGGIKRTFTEITRSEIMNYRSQLDEFARRFYSQGPGAVGEDLDKGSELLGSFEKELAKHEKNRQELANAEKLFDLPITMYPELIKVQKEMTGLRMIYELYNSLKLAKEEWSQTLWINLNVQYLQEGIEGFLKNLRKLPRQVRGLSVAFHLEVKMKAFKDSIPLLLDLKHEALRERHWKELMEKTGVFFEMT-ETFTLENMFAMELHKHTEVLNEIVTAAVKEVAIEKAVKEILDTWENMKFTVVKYYKGTQERGYILGSVDDIIQCLDDNTVNLQSISGSRFVGPFLQTVHKWEKTLSLIGEVIEIWMLVQRKWMYLESIFIGGDIRSQLPEEAKKFDNIDRIFKRIMGETLKDPVIKRCCEAPNRLHDLQTISEGLEKCQKSLNDYLDSKRNAFPRFFFISDDELLSILGNSDPLCVQEHMIKMYDNIAMLRFHDGDSGEKLVSAMISAEGEVMTFRKIIRADGRVEDWMTAVLHEMRRTNRLITKEAIFRYCE--DRSRVDWMLLYQGMVVLAASQVWWTWEVEDVFNKVK-QGDKQAMKNYGKKMHSQIDDLVTRITMELSKNDRKKYNTVLIIDVHARDIVDSFIRGSILEAREFEWESQLRFYWDREPDELNIRQCTGTFSYGYEYMGLNGRLVITPLTDRIYLTLTQALSMYLGGAPAGPAGTGKTETTKDLAKALGLLCVVTNCGEGMDYKAVGKIFSGLAQCGAWGCFDEFNRIDASVLSVISSQIQTIRNALIHQLTTFQFEGQEISLDSRMGIFITMNPGYAGRTELPESVKALFRPVVVIVPDLQQICEIMLFSEGFLGAKTLAKKMTVLYKLAREQLSKQHHYDFGLRALKSVLVMAGELKRGSADLQEDVVLMRALRDMNLPKFVFEDVPLFLGLISDLFPGLDCPRVRYPDFNDAVEQVLEENGYVLLPVQVDKVVQMFETMLTRHTTMVVGPTGGGKSVVINTLCQAQTKLGIMTKLYILNPKAVSVIELYGILDPTTRDWTDGVLSNIFREINRPTDKKERKYILFDGDVDALWVENMNSVMDDNKLLTLANGERIRLQAHCALLFEVGDLQYASPATVSRCGMVYVDPKNLKYQPYWKKWLQQIQNKVEQKYLNDLFEKYVPTLIDMIIEGIVDGRQGEKLKMVVPQTDLNMVTQLTRMLDSLLE-------------GEIEDLDLLECFFLEALYCSLGSSLLEEGRVKFDECIKRLSSMPTVDSE-GNWARPGELPGHLPSLYDFHFDAKRNHWIPWNKLVPEYVHSHEKKFVDILVHTVDTTRTTWILEQMVKIKHPVLFVGESGTSKTATTQNFLKNLNEETNIVLIVNFSSRTTSLDIQRNLEANVEKRTKDTYGPPMGKRLLVFMDDMNMPKVDEYGTQQPIALLKLLLEKGYLYDRGKELNCKSIRDLGFIAAMGKAGGGRNEVDPRFLSLFSVFNVPFPSEESLNLIYYSILKGHTS--TFNESIGGVSRKLTFCTLTLYKNIVQDLPPTPSKFHYIFNLRDLSRVFNGLVLTNPDRFQTVSQMVRVWRNECLRVFHDRLINEVDKELVQNHIGNLVTEHFN-----------------------------------------------------DDFEMVMRDPILFGDFRLALQEGEPRIYEDIQDYEAAKALFEEILEEYNEVNTKMNLVLFDDALEHLTRVHRIIRMDRGHALLVGVGGSGKQSLARLAAFTAGCEVFEILLSRGYSENNFRDDLKNLYMKLGLENKMMIFLFTDAHVAEEGFLELINNMLTSGMVPALFAEEEKDNILGQIGQEALKFGMGPAKESVWQFFVNKSANNLHIVLGMSPVGDTLRTRCRNFPGLVNNTGIDWFMPWPPQALHAVAKSFLGDNSMIPDEKLEELVEHVVMVHQSVGEFSKQFQQKLRRSNYVTPKNYLDFINTYSKLLDEKTQYNIAQCKRLEGGLDKLKEATIQLDELNLKLAEQKIVLAEKSAACEALLEEIATNTAIAEEKKKLAEEKAIEIEEQNKIIAVEKAEAETALAEVMPILEAAKLELQKLDKSDVTEIRSFAKPPKQVQTVCECILIMKGYKELNWKTAKGMMSDPNFLRSLMEIDFDSITQGQVKNIKGLLKTLNTTIEEMEAVSKAGLGMLKFVEAVMGYCDVFREIKPKREKVARLERNFFLTKRELERIQNELAAIQKELEALGAKYEAAILEKQKLQEEAEIMERRLIAADKLISGLGSENVRWLNDLDELMHRRVKLLGDCLLCAAFLSYEGAFTWEFRDEMVNQVWQNDILDRDIPLSQPFRLENLLTDDVEISRWGSQGLPPDELSVQNGILTTRASRFPLCIDPQQQALNWIKRKEEKNNLRVASFNDPDFLKQLEMSIKYGTPFLFHDVDEYIDPVIDSVLEKNIKTSQGRQFIILGDKEVDYDSNFRLYLNTKLANPRYSPSVFGKAMVINYTVTLKGLEDQLLSVLVAYERRELEEQREHLIQETSENKNLLKDLEDSLLRELATSTGNMLDNVELVQTLEETKSKATEVSEKLKLAEKTALDIDRLRDGYRPAARRGAILFFVLSEMALVNSMYQYSLIAFLEVFGLSLKKSLPDSILLKRLKNIMDTLTFNIYNYGCTGLFERHKLLFSFNMTIKIEQAEGRVPQEELDFFLKGNISLEKSKWKKPCTWLSDQGWEDIILLSQKFSDIFGNLPLDIEHHLPMWQEWYDQDSLEQFPFPLGYDDNITAFQKLLILRCFRVDRVYRAVTDYVTLTMGEKYVQPPMISFEAIFEQSTPNSPIVFILSPGSDPASDLMKLAERSGFGGTRLKFLAMGQGQEKVALQLLETAVARGQWLMLQNCHLLVKWLKDLEKSLERITKPHPDFRLWLTTDPTKGFPIGILQKSLKVVTEPPNGLKLNMRATYFKISNDMLEQCPHTAFKPLVYVLAFFHAVVQERRKFGKIGWNVYYDFNESDFQVCMEILNTYLTKAFQQRDPRIPWGSLKYLIGEVMYGGRAIDSFDRRILTTYMDEYLGDFIFDTFQPFHFFRNKDVDYKIPVGD--IKDKFVEAIEALPLANTPEVFGLHSNAEIGYYTQAARDMWGHLLELQPQTGESSSGVSRDDYIGQVAKDIENKMPKIFDLDQVRKHLGLSITPTSVVLLQELGRFNKLVIRMTRSLAELQRALAGEVGMSNELDDVARSLFLGHIPHIWRKLAPDTLKTLGNWMVYFLRRFSQYTLWVTEGEPSVMWLSGLHIPESYLTALVQATCRRNGWPLDRSTLFTQVTKFQDADEVNERAGQGCFVSGLYLEGADWDIERGCLVKSKPKVLVVDLPILKIIPTEGHRLKLQNTFRTPVYTTSMRRNAMGIGLVFEADLFTAKHISHWVLQGVCLTLNSD-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "E7FGT8-1", "uniprot_id": "E7FGT8_DANRE", "id": "E7FGT8-1", "name": "", "aln": "-------------------MAHDDSRVEWIKNAVCVMYDLPDSGCFDELLSRGDGEEEQKIKHFLNVVTEEEVALTLFF---FKNVREEEIEVEIPAANSTKPFHIPQDPVEGEENDSERSPSASSERTLLSDREKTPADKKRKGQKRKS-----QESSNPEDSQSQNLAVEGLSETTEN-------------------GDKPLRNFEIQVVYHVELHVEVNIIPERFEKY-------------------NVLYFLRNTKETITEPVDINEANHLMPRLIEFGMMNDHPLKMLSGLLNHVYIPRLSANQQRLTNGGYQGVAGSEDND------------------------------------------------------------------------------------------------------------ISKTTE----GEKQQPVESRGSFEVRDDLLHSTHKFLQVIDQTLRQLEGEFKLHMPEIDLEGEVELFLSNSV---------------MVDKLEQCVMNWHTQITIVIEEQKRKKPQGPGPLAEIEFWRERVAVFSSLIEQLNLQAVKKILEVMTRADSFIMQELEKTTAELRKYYDESVSNVQFLTTVERHFRNLVTGVDFKVVLETIPELINGLRMIWILSRCYNTDERMEALMERIAWELSERVARVVDVHVLFKEKRVVAKAKVQDGKRVLDIWKACYFEVRARIENSERDPRWEFNRRKLFEKTDYMASICQDLYSVLQTLDEFYIIFGPELKAVTGDPKRIDDVLHCVN-SLVKPIEEVTFDPFDNRKMTSWKMVMQEFNNEVQVIEREAITFIDHSFKTLRSSSAAFDLLLKFKNIRCRDAINDQLMKKFSDILAQYCKEMVLINDIFVKFKDNPPLSKNHPPMAGAIIWQRFLLDQMRYPMKRFREDRD---LMNNQEGKAVESKFIEVASRMRQYEVDLYNKWKADTNQTLPILMRKSLLVMVNSYG--------------------------------------------------------TVCADSTRH--------------------------------------------------------------------------------------RTGSEKVLERDVRFSVNFPPELQEIISEAKCLDRIGIVLPDELQNVALQEEVFLRYINGLKKLVRRYHLLMDNLNDAEFLLMADQVQELRQVLSVGCKRINWNNLGIPQFIQRGNQAASKFESLENQIQKNERDIDDKLKSIESANLF---------------------------------------------KFPLADQTGYLPG-----IREFCEFIESERAKTVNLLVNMYAAISPLLTKMESLIMGTSTGKAKGMAQFYAYWERKIFDSLTKMVFQNIQAFNTALMGNTPLFQIDTILAAPEIALLPKSSEVYKLIRQCVGDCVETTKRFVRWMHGSCIQCPPQHVDGEDESFLFTFYSDICQLPQINEQATAVSQTIQRLLNGISVYLKSWMSYRSLWKLDKAIVMEKFAAKKPSCVMYDEKFQFYVKVSNEVAKQPMVKHEHIIRLNLEPLARAVQENIQVWVTSLGKLLNDSAREELFNLRNELLILSENLKRSPNTLEDLKFVLVTITDIRDMSLSVEMRINDAQERYRTLSMYIVETTEEEMQLSANISILWNDLFMESRQVDRSLVKVKKTFAEITLNQIEEYKQELFIFAESFNMHGPGAVGDDLEKGLQIMSTYETELVRVEARRQELAKAEKLFNLPITMYPELLNVQKEMRGLRQIYEIFKSQKEAKTEWSQTLWVNLDIQLLQEGIDGFIKSLRKLPKDARALPVSFFLEGRMKEFRESLPLLLDLKNKALRERHWKSLMERTGTNFEMNPNTFTLENMFAMELHKYGNVISEIVTSAVKELGIEKGVKEVEETWDSMKFTVHRYFKGTQEHGFILGAVDDILQHLDDDAMNLQSMAGSHFVGPFLATVQQWEKNLSLISETIEVWMLVQQKWMYLESIFIGGDIRSQLPEEAKKFDNIDKTFKKIMTDTVKDPGIKRCCLVPNRLADLQNLSDGLERCQKSLNDYLDSKRNAFPRFFFISDDELLSILGSSEPTCVQEHMIKMYDNIAALRFDTGMNGEMVANALVSAEGEVMELKQPVPAEGRVEDWMTAVLLEMRRTNRLITKEAIYFYSH--QKSRVDWMLDYQGMVVLATNQVWWTYEVEDVFRRMN-EGEKQALKQYAKKMHQQINDLVKRITEPLKKNDRRKINTVLIIDVHARDIVDSFVRDSITDAREFEWESQLRFYWVKEPDELFVRQCSAQFCYGYEYMGLNGRLVITPLTDRIYLTLTQALSMFLGGAPAGPAGTGKTESTKDLAKALGLLCVVTNCGEGMDYMAVGKILSGLAQCGAWGCFDEFNRIDASVLSVISSQIQTIRNALMLHLQRFHFEGQEISLDNRIGIFITMNPGYAGRTELPESVKALFRPVVVIVPDLQQICEIMLFSEGFLVAKVLAKKMTVLYKLAREQLSKQSHYDFGLRALKSVLVMAGELKRGSPNLSEDVVLMRALRDMNLPKFVFEDVPLFLGLISDLFPGLDCPRVRYPSFNDAVEAILEENRYIMMPSQVDKVVQMYETMMTRHTTMVVGPTGGGKSVVINTLCQSQTRLGLLTKLYSLNPKAMSVIELYGILDPVTRDWTDGILSNIFRDINKPTDKKERRYILFDGDVDALWVENMNSVMDDNKLLTLANGERIRLQSHCALLFEVGDLQYASPATVSRCGMVFVDPKNLRYAPYWEKWVNSRAPK-EKADLCKLFEKYVPSAIDMIVDGVVDGKQTEKLKTVILQTDLNMVMQLTVMVDSLLE-------------NEDFLFEELECCFLEALYCSLGASLLDKGRQKFDAFIKKLSSLNSVHDE-KVLAGPGEIPVYLPTLYDFHFDGTQKKWVPWSSMVSKYIHNPEMKFIDILVPTVDTTRANWLLEQMVKVKRPVVLVGESGTSKTATIQNFLSNLNTDTTIMMTINFSSRTTSMDLQRTLEANVEKRTKDTFGPPMGKRLLVFMDDLNMPRVDEYGTQQPIALLKLLLDRGGMYDRGKELNYKLIKDLGFIAAMGKAGGGRNEVDPRFISLFSVFNIPFPEEESLHLIYSSILRGHTK--PFEECIRNICDKLTFCTLELYKTIIKDLPPTPSKFHYIFNLRDLSRVYHGLTLTNPERFCTVTQFVRVWRNECLRVFHDRLINETDKIMVQGHVKNLVEEHFK-----------------------------------------------------SDLDSAMRDPILFGDYRTALK-SEPRVYEDILDYDASKALFQEILEEYNENKTKMNLVLFDDALEHLTVIHRIIRMDRGHALLVGVGGSGKQSLTKLAAFTAGYEVFEIVLSRGYSETNFRDDLKTLYLKLGIENKKMVFLFTDAHVAEEGFLELINNMLTSGMVPALFADDEKESVLNQLRDEAMKSGCGPSKESIWQYFVNKSANNLHIVLAMSPVGDTLRTRCRNFPGLVNNTSIDWFSPWPLQALYAVAKSFLGESPMIPKSHSEAVIDHVCMVHSSVGDYSKLFLQTLRRSNYVTPKNYLDFINTYSNLLEDKDKYILAQYKRLEGGLDKLKEASGQLAELNVKLDEQKVVLAEKTSACEILLEEICANTAVAEEKKTLAEEKAKEIEEQNKVIVVEKKDAESSLAEALPALEAARIALQDLDKSDVTEIRSFTKPPKQVQTVCECILVIRGYKEINWKTAKGMMSEGNFLRSLMEMDCDSINANQVKHVKAYLRNLNTSLEEMQGISKAGSGMLRFVEAVMGYCEVARDIKPKREKVARLERNFHQSKRELERIQNELGAIQKELRALGDKYEGAMTEKQLLQEEAEVMERRLVAADKLISGLASENKRWIKDLEELKQRRVRLLGDCLICAAFLSYEGAFSWDFRNEMVYKVWQADVLERGIPLSQPFRIENLLTDEVEISRWGSEGLPPDELSVQNGILTTRSSRFPLCIDPQQQALNWVKKKEEKNNLKISSFNDPDFLKGLELAIKYGFPFLFQDVDEYIDPVIDNVLEKNIKGAEGRQVVVLGDKEVDYDPNFKLYLNTKLANPKFLPAVFGKAMVINYTVTLKGLEDQLLSVIVGFERKELEEQRERLILETSENKRLLKDLEDSLLRELATSTGNMLDNVELIQTLDETKSKANEVFEKLKLAEKTAVDIDTLRDGYRPAAKRGAVLFFVLAEMALVSSMYQYSLASFLEVFDLSLSKSLPNPILPSRLKNIIDTLTQNVYNYGCTGLFERHKLLFSFNMTIKIEQAEGRAPQDELEFFFKGNLSLEKSKRKKLLDWLPDQGWEDIIRLMELFPNEFGTLADDIEKNPEEWKNWYDLDAPEQASFPMKYKENLSPFQKLLLIRCFRLDRVYRAVSDYVTLTMGEKYVQPPVISFEAIFDQSSPNSPIVFILSPGSEPASDLMKLAKHSGFGVNRLKFLAMGQGQEKVAFQLLDTAVARGQWLMLQNCHLLVKWLRDLEKTLERITKPHPDFRLWLTTEPIKDFPIGILQKSLKVVTEPPNGLKLNMRATYFKISHDKLMNCAHPAFRSLVYVLAFFHAVVQERRKYGKIGWNVPYDFNESDFLVCMEILDTYLTKAQNQGDEIIPWGSLKYLIGEVMYGGRVIDSFDRRILTVYTDEYLGDFIFDTFQPFHFFHNADVDYKIPALG--PKQVYVDEIESLPLANTAEVFGLHPNAEIGYYTQAARDMWTHLIELQPQTGDSGGGISRDEYISQVARDIQSKLPEVFDLDVIRKKLGLEISPTSVVLLQELERFNKLTVRMSRSLAELQRALAGEVGMSSELDEVARALFNGQIPVIWRKLAPDTLKSLGNWMIHFKRRHEQYSSWVNEGEPYVMWLSGLHIPESYLTALVQATCRKNGWPLDHSTLYTQVTQYSSEDQVKERPGQGCFVSGLYLEGADWDIDNGCLVRSKPRVLVSQLPILKIIPIEARRLKLQNTLRTPVYTTSMRRNAMGVGLVFEADLYTTKHISHWVLEGVCLCLNSD-", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VAV5-1", "uniprot_id": "Q9VAV5_DROME", "id": "Q9VAV5-1", "name": "", "aln": "MSQTQFESTSDSADATAESLNNVEPRIVWLKTIMSNMLGVFEPKYVNATISKNMPAVENFFQRRYETQNDLDFVVLFFWRTFYDKLIEEEITVLEEVPRP--PPTVPDKKGKGKKKGDARMAGGKSAGKAGASAGAAGKGRKKAGQDAAAPAGGDQEAVEEVNTGGETTDAEVEGELEGEEEATVAGSGKSSARSRPSSDTENGSKFRKKKATYVPVYVEVKKLVPAYVKTPQVHCHFGRMESCDLDPKIKYIYIVRKNRREIPNFSDVSACFAQMPLYFLLGTVRGSLINSLRDDLNLVYKSAIQFQFREPATADSQQMDSYEGQAGGSGGGGAGGPAGETGEDISSEAKESGPGLLELSKPSEFRLRALKQQKKMKEKEAAAKKAKAKKTDAEPTEEEEEADAHKVEAHLSSSEEEVEIKVEKLTIGQRWEKMLNETKAKVEAEHAAEEATPPRITPIQRRLLKEIEEFQSEITWTINHIVWAFSLPSSYILPGQEATEFEDAIIRVPVDPKRLDLVITYTQQQLEEVVDGWIKYLKKTMKTLTDAKLDDFTPMAEHRYWHKMEVELYGTLEQLKTEFVVAVLQRLTDDKSPVLDEWQAVVEKTEARFKLAKENSDYLGTIIDYLEKVRSYESFKMVVLQIPNIMVGLRHIWTMSSHYCRDPEMQVLLCQISNVFVQKVKSIINFENIFKYSATYTYETATNCANLLRCWKQAYKLSRQHIEDSGAGSRWEFDRVALFNEVNHIHRVAVDIAYVGRVFVQYENLFGHRLKACIADPSIVDNLMRKVYRMLDDLIKSVDYDMFRPGNWENWEYSLELFNKRLDNVENEAKNVIDQSINSLLSSEKGLDLVVNAMNIDTRATLQEFVATKHENLLRFFVTEINAVERVFTKLKKSPPMAKHQPAKISAIFWARLLGKKLKTSVLAFKRVEDEPAIKNSFLKRSSFKQYFELMTVMFQFEKVLFENFIQNATYLVNTTNRSNVLRIRICKESTMSYISEAVQTLKAKPRPELQMTSDRRVTPVKSSNLMPVQSEAFSAYSVADSAGTEISSESENEGLLVGDTSQKKLMCRINRLTVLVAMIMWMVSNTRKANIQLQECTAFIKMVKDKKPKDVTAMDRHCVRTCELLQRAESQYLLPIWRELVGEKTLIEYDMDFVVNLKRDVFDVLFEAQQFEHLGFTLPAVLRTAIMKKDLLFKDYERMTEVVDRYRSIINNLSMSEVIFLRGHIYDTELFIQMGVGRYTWTSFNIGKFCDQINSQLRKLTSIVSQINFIRLDLRSRIDMIKSFNLFNLDDELKVEDTSRSSGESYLQDRKNPSQRFKSVTGETITMFSVEKDVPADEKAEQACGSGIYPCQGYFELLEASRNRKAAQMKKLYDSLGPVLVKLESLVLGTFSGRSDRMKTYYEYWEGETFKCIVDMTYQNLKCYINRLLSNKPMFEVNAVLLMSEIVLEPSVQELQNTIVTATKDYISRLRIFTRWMTGTCIACPLVEMG-KQFKYNYTYYEDVIQIRSIVDLVINIHDLASRVANEARGFVSQFRKYFNLWAFEKSFICQKFLEKQVTLIEIDEKFTFYSSIVETLANTRKFQDIKCVRINLEPLLASITQHAQDWCTTLGEELLRHVNDNMRAMRNEVKTLSLNLNKTTRELEDFKLVMTTIGTVQSSTLTNEQKIHEMQETFTILSEHKIMFPYEDMLMAHHLEKRWKRLFLSALYRYEKLQPIKQKFADMTSVEIDEFCDDLAEFIKDYDENGPGSVGAELERGVRLMDPYGQKIAERESRREELANAERLFDMAMVDYHEFARVQTEFEGLQQLYKLYKAQKYAREGWGKTLWADLDPNVLTEGVESYLKEFRKFTKAVRTLPVGVQLEIHMKQFKGTVPLMVSLKHEALRERHWLQLMEKTGQYFDMSPARFTLENMFAMQLHKYQEIAEQILTNAIKELQIERGVQAVIETWASMAFKTFKHFKGSDDRGWVLGPVDEIMQILEDNAMNLQSMGASQFIGPFLETVNKWERTLALISEIIDEWLVVQRKWLYLEGIFIGGDIRTQLPEEARKFDDIDKSYRRIMVDCAKNPLVVPFCTVPGRLVEIQGLGIGLENCQKSLNEYLDSKRRIFPRFYFISTDELLSILGSSEPSAVQNHIIKMYDNIKSLRLVK-EGSQTIVTGMISSEGEVMEFRHSARAAGRVEYWMNDVLDEMRRSNRFINKTAIYDFGTDLQISRPDWLMNYQGMVGLAASQVWWTAEVEEAFDQAQNHGNMRAMKDFLGKNNYQIEELVLKVRSNLSRNDRLKFKAQCTVDVHARDIIDNFVRDNVLDASEFSWESQLRFYWIKFYDNLHVLQCSGSFDFGYEYMGLNGRLVITPLTDRIYLTITQALLMNLGGAPAGPAGTGKTETVKDLAKAMGLLCVVTNCGEGMDYRAVGTILSGLVQCGAWGCFDEFNRIDISVLSVISTQLQTIRNGLIRKLDRFVFEGVEIHLDPKCGVFVTMNPGYAGRTELPESVKALFRPVTCIKPDLELICLISLFSDGFLTAKVLAKKMTVLYSLAQAQLSKQCHYDWGLRSLNSVLRMAGVMKRQSEDLPEAVVLMRVLRDMNFPKFVFEDVPLFLGLIKDLFPGIDCPRIGYPDFNAAVRHVLVNDGYILLPDQEDKVVQMYETMMTRHSTMLVGPTGGGKTVVINALVKAQTHMGLPTKCLVLNPKACSVIELYGFLDMETRDWIDGLFSNIFREMNKPIEREERRYACFDGDVDALWIENMNSVMDDNKLLTLANGERIRLENYCALLFEVGNLNYASPATVSRAGMVYVDPKNLRYSPFWQRWVLTRPEP-QRELLNDFFEKIITQSIAFILEGLDGTTQGNPLKLVIMQTDLNMVTQFCNLYDALLPNYVMDSKNYDEPVQQNYNTDSLECCFLQAVYGSMGACLVEKHQPVFDEYMKRISGFPLVQDTPENPASGGQFPQSKPTLYDYFWDVKDNVWKAWEWVVQPYTHDPQVKFSEILVPTVDNTRTNRTLSLMSEIKRPVLLVGEAGTSKTATIMQYLRNLNPSVNVILNINFSSRTSSLDVQHTLEAAVEKRTKDTYGPPMGKRIACFIDDMNMPQVDDYGTQQPIALLKLFFERGGMYDRDKDLNWKKFKDLTFYAAMGTAGGGRNEVDPRFISMFSTYNIIFPNDESLIQIYSSIFKGHMVFVKFQPEYMLIADMIVHMTLKLFKMVIVDLPPTPSKFHYIFNLKDLSRIFAGMLLIEPTCFKGLRDLIRVWRNEYTRIICDRLITDNDIANVRRNLAVEVAERFPPTFEEEHGFIDAAAAEAEAQARLLYEPSKADIDGGEEEGEEEEEGEEAPQVILSLKDYVLRDPLLFGDFRNFTNESEPRLYEDLLDYNSVYFLFTEILEEYCERKQKMTLVLFEDCLEHLTRVHRTLRMNRGHVLLIGVGGSGKKCITRLAAFAAECDVFEITISRGYNEAAFREDLKVLYTIAGVKRKKVVFLFTGAQVAEEGFLELINNILTVGQVPALFPDEDKDGIVNQVRKFAEEDGVSASKDAVWGYFLRTCAENLHVVLCMSPAGDALRNRCRNFPGLIGSTYIDWVFPWPRQALYAVAKLFLTEHRLIPASHREAIVEHVVHVHTSIQQYSKDYLAKLRRNNFVTPKHYLDYINTYRGLLEEKAKFITQQRSRLGEGIKKIEEASVQIDELRIIVTEQKKNVAVASEECEAMLVTIESSTQKANVKKAEASEKSVEVEIKGKQIAIEKDEAEEILAEAMPALEEARLALSQLEKAQITEIRSFATPPAAVQVVCECVAILKGYKEINWKSAKGMMSDVNFLKSLMEMDCEALTQKQITQCRQHMKTGN--LEDMAKISVAGAGLLRFVRAVLGFFDVYKEVKPKKERLDFLVEEQEVQIKLLNHLNGEIQKLEEKLNELNENYATSMKQMRALTEMMQQAERRLIASDKLISGLTSELIRWSKEMASLGQQLIDSVGGCLISASFLAYTGAFTWEFRKAMVFDDWLEDIASLGIPIQLPFKIDGYLTTDVEISQWSNEGLPPDELSIQNGILTMRASRFPLCIDPQLQALQWIRKREFKNNLKVLSFSDSDFLKQLEMAIMYGTPVLFEDVDDYIDPVIDDILQKNIRIQGGRKFVMLGDKEVDWDPSFRVYLTTKFSNPKFDPAVYAKALVINYTVTQTGLEDQLLSVVVGTERPDLEAQRESLIAQTSENKQLLQQLEDSLLRELSTSTGNMLDNVELIETLENTKTKAGVVMEQLKLAADTAADIEVLRNGYRPAAKRGAVLFFALSDMATVNSMYQYALAAYLDVFVYSLRKAVPDASLNKRLNNIIKTLTENVYCYGCTGIFERHKLLFSFQIATKLAQRDGILLQSELDFFIKGSIALTKSERSNPCKWLSEKSWEDVLKLAFDFPDIFGTLPDHFGRYLTEWKEWFDLENPEEVPCPGDYNIKCNAFQKLMFLRCFRVDRIFRSINQYIVETMDEFYIMPPVVSFSAIYEQTSSTIPVCFVLSAGSDPTNDLIKLAD-TIVGMSNFCHISLGQGQEKAALRLLDGAIKQGMWLMLQNGHLLIRFVRELEKHLDRIENPHPDFRLWITTDPTPTFPIGILQKSLKVVTEPPNGLKLNLRSTYFKVRQERLESCSHVAFRPLVYVLAFFHAVVQERRKYDKLGWNIAYDFNDTDFDVCTEILRTYLTRCGTG---KIPWNSLKYLIGEVMYGGRVIDDFDRRITNCYMNEYMGDFLFDEFKVFHFYEDDNVDYCLPEEETILKEDYIAHIDKLPLVNKPDVFGLHPNAEIGYYTMAARNIWNSLIELQPQTGEGTGGISRDDFIDSVAAGILKKLPPAFETWRIRKQIQMSLSPTGVVLLQELDRFNLLVVRIKKTLELLRKAIAGEIGMDNVLDNIANSLFNGLLPAAWSKLAPATCKQLASWLEHLRLRAVQYKYWTLSGEPLVMWLSGLHIPQSYLTALVQIACRRNAWPLDRSTLFTYVTKFADPDDVEERPVTGCLVHGLYIEGGRFDLATNQLARSHPKVLVEELAILAVEPIEAHRLKLQNTYLAPVYTTSLRRNAMGVGLVFEANLATSEDLSHWILQGVCLTLNTDT", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : **: * : .: . . . . : . . . : .: * : . : : : : : : . : ::::*..: *.: *:. . ** : * :. :: * . : *: . :. : :. . . * . . : :: :* . .:* . * *:.:: :.* . * : : : **: * * :. .:. . :. *:** .:*:: . : . ** : * :*: :. .* : : : : . : .* :* *: ::.:: .*::*: ** :: .** :* :* * * .* *: :*: : ::* :::.. :** . . : .. : . * ** .* * :** * ****:* **:..::: :. *: * : : :: :** .*** .**. :*::: * * ::.: :* * . *: :: *: .: :: :*.: ..**: *::*. .** * * * ::: .: * . .: : :. : .:::*: * ::* :::: : : :..:* : ::. :: . * :*: : ::: *:: ::::*:.:* :.. :::: ::: : .:: :*: ::..*. :* :: .: : .: * * .*..:.* .: :. *: :: **: *: .:: *:: .** * . * : : * :* .* . : . * ::.*:*.*:*.*:: * :*:: : :* *** : :. :..: :*::.: . :: * *:*. :::* .** * *. .*: : .. . :. : *.*** *:** ** . :: .:*.*: .* : . : : *: ::. : * ** ::*::: :** *: . : ***: ** .: : . .:. : :*::*. * :: :: : * :**: * ..::: :::*: *: **.: . ***:*:*:.** ::. :* * : .: ** : :: : : . : : ::. *. ** .: . * :*:.*:::* :* :: :: * . : .***:** :*::* .::. : ::.. * *:***:**:**::.:. * *: .**.*: **: :*::::. * *: *.:*** :*: : * **::.::: :**:.: .* *.* ** :** *: ::**::.**::***:*** .***:*. *:*. *********:***: :: .:*:* *:**: **:.*: : :** .* *.. :: **::::*::**.**:*:* *:*::.****:..*:*:**** **::**:.*:**.* *: *::**:**:***.********:******:***:**: :::** : *:* : * .*.** ::* :. ***.******:******. ****:*** ********.*:* .**:*:******* **: ..: :...::*:***** ::: * **** **. ** ****:**:*.* **: : : ** **:: ***** **:.***** ***:.* : : .*: :*:*:: * : **::** :: *.:*** * :: :*******:*.*:*..: :* **.********* : *:* : **:. * :***********************:**** * ***************:.******:*************** ***.*:***.*************** *******:*:*****.*: :* * *** ** ** : *:*:***********************. * ***: ** * ***:*** **.*********.**: ***** ***:***:*:*** *** :** * :* * *****.*****:***************.*****:****: **.** **. :* :: * ::* * ******:***:***:**:**** ***:****:* ::**::*: ** ***** *******:** **** **::*****::*:* :::**:* *********:**********:************: :********:*:*********.***:******:* *:*::*: :: * .:*** :. : .*::*: . * : ** :: ******* *: : *:** : : *** **:*:* *:*:.*::. : ** :*:::.: *. * *::* *:***:.:* . : * .*. :* * * : ** :*** ***.**:. *. * ::*:**::***:******* ::* **. ...::: :******:*:*:*:.*** ********:*******: *:**:***:**:************::::* :***.*:** * ::** * ****.************:*:**.:*: **.:*** ** **::** *. :. :.. ** *:* :: ***************:****:: *: * :* * : :::****** *:: ****.: * *: :: * *:* . : .:***:****:: : .***:***: **:: ** ****** * : **.****:*.***** :** :**:***.**:*******:.:::****:* :**** :****.* **:*** ** *::.* ::****.*:************:** * *****.:::*:.::.*: . * : * ..:*:::* :*:...*:***:** ***.**:**. ******::..* ***. *** ***:**** ** :** .: * ::.** ** *: .:*: : .***.*:****:***:**** **::* : * .** *:.*::**: *: **. : *** :* : ** :* * .* *: ** *.**: *:* :.* *.:** :** ***.:* ** *:: *..*:*:::******:.** **.****: :::****:***:***:**: ***:****:* :::. *:.: : ::. * *:* :* ** *:*:**.**:*: :* :::***:*:: * .: : *::::.*: ::::*. *. :* :: : : * * : ****:*:******* ** ** ::: .* :: : :*.**:.*:**:* ***:*:**. ** * *: . **:. **:::. ** :****:*..:********:****** *:********** ***:*::::* ****:: **.*.**** **::* ** *.**.***:*******.:*:***: **:.::*******:*..*::**.**::**:: *:*:.**:******* .*********:*. ** :** *** ** :*****.**::*********:**********:*:.**::**:** * *:**** .** **: **:******:***:***.*::** *.*****:* ::*:** ** *::*:. * .**.**:.*** .:* :****:**********::: *: * :* *.**:**:**.::* **: .: **.::.***:: * *.: ** *. .. . *::*:* : *: . * *. : ..****:::****:**::*::.:*:. **.* *: **::**.**::*::. *: *:**.**:*:.**:***. : .* ..: .:::******.*::**: *: :* ****** ***::::::*** *:** :********:**:* ***********************:*:****: :: * .*.* **:.*****************:.*:***: ****::** ** *** ****:. ***.**************.**.***** . * :**:***:** *: ***:.: :*** :* *: :: *: ***.*..:*****.******** ***::* *:*******:. .*:***::*..** * .*:* *: :**:: ::**.******* *** *.:*:.::* *::*:***:**.. **::*.:** * :* * :*** * * *..*: :: * ** *. ..** **********:******** :**:*.****:***:* **:: . *:*:**. **:* ***:**. :*: . * :*:*:*** :*.** : * *.:******* :******:******:******:* *:..:***:*:**** **:* ", "identical_positions": 1952, "similar_positions": 1344, "identity": "38.34%" }, { "cls_id": "homologset.agr.MGI:1860303", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8R4T5-1", "uniprot_id": "GRASP_RAT", "id": "Q8R4T5-1", "name": "General receptor for phosphoinositides 1-associated scaffold protein", "aln": "MTLRRLRKLQQKEEATAAPDLAGRAPDSEAARAAPTPS-GPPAAAAPPGAPGDELYAALED---YHPAELYRALAVSGG----------------------TLPRRKGSGFRWKN----FTQSPEQQRKVLTLEKGDNQTFGFEIQTYGLHHREEQRVEMVTFVCRVHESSPAQLAGLTPGDTIASVNGLNVEGIRHREIVDIIKASGNVLRLETLYGTSIRKAELEARLQYLKQTLYEKWGEYRSLMVQEQRLVHG----------------------------------------LVVKDPS-----------------------------------IYDTLESVRSCLYGAGLLPGSLPFGP-----LLAAPGGARGGSRRAKGDTDDAVYHTCFFGGAEPQALPP-----PPPPARAPGPGSAETP------------------------ASVLCPA--------------------------------------------PRATLSRSASVRCAGPGGGGGGGAPGALWTEAREQALCGAGLRKTKYR---------------------------------------SFRRRLLKFIPGLN-------------------------------------------------RSLEEEESQL---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9JJA9-1", "uniprot_id": "GRASP_MOUSE", "id": "Q9JJA9-1", "name": "General receptor for phosphoinositides 1-associated scaffold protein", "aln": "MTLRRLRKLQQKEEATAAPDPAGRAPDSEAARAAPLPS-GPPAAAAPPGAPGEELYAALED---YHPAELYRALAVSGG----------------------TLPRRKGSGFRWKN----FTQSPEQQRKVLTLEKGDNQTFGFEIQTYGLHHREEQRVEMVTFVCRVHESSPAQLAGLTPGDTIASVNGLNVEGIRHREIVDIIKASGNVLRLETLYGTSIRKAELEARLQYLKQTLYEKWGEYRSLMVQEQRLVHG----------------------------------------LVVKDPS-----------------------------------IYDTLESVRSCLYGAGLLPGSLPFGP-----LLAAPGSARGGARRAKGDTDDAVYHTCFFGGAEPQALPP-----PPPPARALGPSSAETP------------------------ASVLFPA--------------------------------------------PRSTLSRSASVRCAGPGGGG--GAPGALWTEAREQALCGAGLRKTKYR---------------------------------------SFRRRLLKFIPGLN-------------------------------------------------RSLEEEESQL---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q7Z6J2-1", "uniprot_id": "GRASP_HUMAN", "id": "Q7Z6J2-1", "name": "Protein TAMALIN", "aln": "MTLRRLRKLQQKEEAAATPDPAARTPDSEVAPAAPVPTPGPPAAAATPGPPADELYAALED---YHPAELYRALAVSGG----------------------TLPRRKGSGFRWKN----LSQSPEQQRKVLTLEKEDNQTFGFEIQTYGLHHREEQRVEMVTFVCRVHESSPAQLAGLTPGDTIASVNGLNVEGIRHREIVDIIKASGNVLRLETLYGTSIRKAELEARLQYLKQTLYEKWGEYRSLMVQEQRLVHG----------------------------------------LVVKDPS-----------------------------------IYDTLESVRSCLYGAGLLPGSLPFGP-----LLAVPGRPRGGARRARGDADDAVYHTCFFGDSEPPALPP-----PPPPARAFGPGPAETP------------------------AVGPGPG--------------------------------------------PRAALSRSASVRCAGPGGGGGGGAPGALWTEAREQALCGPGLRKTKYR---------------------------------------SFRRRLLKFIPGLN-------------------------------------------------RSLEEEESQL---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VRT8-1", "uniprot_id": "Q9VRT8_DROME", "id": "Q9VRT8-1", "name": "", "aln": "MASKPMSTSCQSIATAASSAATTAAAVSISASNATSVGSLIAAACQQEQPHPHQHYSQSQQQHLYHQSHQQASHYVNGTGSLGRLKFHKSLDASDEEIEYAQLSRSTHILGRHKSERYLASNPDEDRRRRTIIVEKKNNSYGFTLQSYGIHYKRDEELEMITYVDYVEYGGPAYRAGMREGDVILSINGKDMEKADHKTIVEFIKQCDTRMRMVVLFEDCVRKVDLHMRYIQLQSMLQQKMNELERVHLRERELLEGKWKTHSLPARKKANANTSPSDGEGVSPTEVAGEAGFYRPALSTEDVPNIAARQHGVGGPGIIPPPAQFMLTYHYLDPTYRYVLRPTHGSSEEFVDGLGLQRSSSDHQPPAQRYVLQQTESVDANSMTQPTTTAPTQYHSTTGGSVKPPAPPPRTCEKHKPPAKPPKPEKEKSSGKHCHVGHSCNPCLGHFRWKSAEKSAVPAPDNVSLDAYDLASPCCDTHCVPSRRRHRQHKEHTHKHKHRDRERVESKEQRVRPKSTSHASPNANGGAGSGHHHHHHHHHHSHEQQQQQQQQQQQQQQQQQQQQQQQPIQTVPHHHHYPHQMHNPCQVQSQSGSTRSRYFDLASGLASHCSLHSCTSSEFATGDTASYTTSISTDTLFWDPTSETAQSRQHSTKSRQSYEQQPQQQQPTHQGHHHHHHHQGDYHQRYHVTTTQMQPQQIYPNTIAYVQKPKSWDNLANKAGFNVGYGYLDTVAVKPAIKMQIAQQRHSMPRRNPYGRYSTYGDVENYAPPPTEFVGELTTTTTTTITAKSTEELLAACDCLTPQQQAAIKAAQYQLSQNQKLSHQNSCQLGYYSHLPRPTTDVGTSTTSQQVHGAGDVQTTSEATRL", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*: : : . *. ::*:. : :. * * *. .**. . .: *: :: ** :. : *.* *.* . * *. ::. *::*: : : .*:::** :*:**:*::.::.:**:*:* *. ..** **: **.* *:** ::* *: **::** ... :*: .*: .:**.:*. * *:. * :* .* . : ::*:.*:.* * .:* . : * * .. : * ** .* . * :* . ..: : : **: *. :* * ** ***:. * ::. : * .: *. *. *.*...* *: . :.:: :: : : * * * :.: .** :* *:: .* ", "identical_positions": 96, "similar_positions": 138, "identity": "11.09%" }, { "cls_id": "homologset.agr.MGI:1860374", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D4ACM2-1", "uniprot_id": "D4ACM2_RAT", "id": "D4ACM2-1", "name": "Mitotic spindle assembly checkpoint protein MAD2A", "aln": "MAQQLARDQGITLRGSAEIVAEFFSFGINSILYQRGIYPSETFTRVQKYGLTLLVTTDPELIKYLNNVVEQLKEWLYKCSVQKLVVVISNIESGEVLERWQFDIECDK----TAKEEGVRREKSQKAIQDEIRSVIRQITATVTFLPLLEVS--CSFDLLIYTDKDLVVPEKWEESGPQFITNSEEVRLRSFTTTIHKVNSMVAYKTPVSD", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9Z1B5-1", "uniprot_id": "MD2L1_MOUSE", "id": "Q9Z1B5-1", "name": "Mitotic spindle assembly checkpoint protein MAD2A", "aln": "MAQQLAREQGITLRGSAEIVAEFFSFGINSILYQRGIYPSETFTRVQKYGLTLLTTTDPELIKYLNNVVEQLKEWLYKCSVQKLVVVISNIESGEVLERWQFDIECDK----TAKEEGVRREKSQKAIQDEIRSVIRQITATVTFLPLLEVS--CSFDLLIYTDKDLVVPEKWEESGPQFITNCEEVRLRSFTTTIHKVNSMVAYKTPVND", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q13257-1", "uniprot_id": "MD2L1_HUMAN", "id": "Q13257-1", "name": "Mitotic spindle assembly checkpoint protein MAD2A", "aln": "MALQLSREQGITLRGSAEIVAEFFSFGINSILYQRGIYPSETFTRVQKYGLTLLVTTDLELIKYLNNVVEQLKDWLYKCSVQKLVVVISNIESGEVLERWQFDIECDK----TAKDDSAPREKSQKAIQDEIRSVIRQITATVTFLPLLEVS--CSFDLLIYTDKDLVVPEKWEESGPQFITNSEEVRLRSFTTTIHKVNSMVAYKIPVND", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VRQ2-1", "uniprot_id": "Q9VRQ2_DROME", "id": "Q9VRQ2-1", "name": "Mitotic spindle assembly checkpoint protein MAD2A", "aln": "MSTAQATKNCITLKGSAQIIVEYLKYGINSILFQRGIYPAEDFNNTQQYGLTILMSKDPKIKTFLQNVLSQTEEWLSKNMINKISMVITNAHTKEVLECWDFNMQAELGDGDISDPTKATTTKELSRIQNEIRDVMRQISATVSYLPLLDCI--CTFDIMIHTLQNTELPAKWDETGAIVIQNPQAVQLRSFSTGLHKVDTVVNYKMST--", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P40958-1", "uniprot_id": "MAD2_YEAST", "id": "P40958-1", "name": "Mitotic spindle checkpoint component MAD2", "aln": "------MSQSISLKGSTRTVTEFFEYSINSILYQRGVYPAEDFVTVKKYDLTLLKTHDDELKDYIRKILLQVHRWLLGGKCNQLVLCIVDKDEGEVVERWSFNVQHIS-----GNSNGQDDVVDLNTTQSQIRALIRQITSSVTFLPELTKEGGYTFTVLAYTDADAKVPLEWADSNSKEIPDGEVVQFKTFSTNDHKVGAQVSYKY----", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .: *:*:**:. :.*::.:.*****:***:**:* * .::*.**:* : * :: ::.::: * . ** ::: : * : . **:* *.*::: .. . . *.:** ::***:::*::** * :* :: :* : :* :* ::.. * : : *::::*:* ***.: * ** ", "identical_positions": 55, "similar_positions": 75, "identity": "26.07%" }, { "cls_id": "homologset.agr.MGI:1860383", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O88875-1", "uniprot_id": "BY55_MOUSE", "id": "O88875-1", "name": "CD160 antigen", "aln": "MQRILMAPGQSCCALAILLAIVNFQHGGCIHVTSSASQKGGRLDLTCTLWHKKDEAEGLILFWCKDNPWNCSPETNLEQLRVKRDPETDGITEKSSQLVFTIEQATPSDSGTYQCCARSQKPEIYIHGHFLSVLVTG--NHTEIRQRQRSHPDFSHINGTLSSGFLQVKAWGMLVTSLVALQALYTL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D3ZBA3-1", "uniprot_id": "D3ZBA3_RAT", "id": "D3ZBA3-1", "name": "CD160 antigen", "aln": "MQ-ILMAPGQSCCALAILLAIVNFQHGGCIHISSSASQKGGRLDFTCTLQYKKDEAEGLILFWCKDRSWNCSPETSLEQLKVKRDPGTDGVIEKSSQLVFTIEQATPSDSGTYQCCARSQKPEIYIHDHFLSVLVTE--NHTEIRQRKRSHPDFSHMNGTLSSGFLQVKAWGMLVSSLVAFQAL---", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O95971-1", "uniprot_id": "BY55_HUMAN", "id": "O95971-1", "name": "CD160 antigen", "aln": "---MLLEPGRGCCALAILLAIVDIQSGGCINITSSASQEGTRLNLICTVWHKKEEAEGFVVFLCKDRSGDCSPETSLKQLRLKRDPGIDGVGEISSQLMFTISQVTPLHSGTYQCCARSQKSGIRLQGHFFSILFTETGNYTVTGLKQRQHLEFSHNEGTLSSGFLQEKVWVMLVTSLVALQAL---", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :*: **:.***********::* ****:::*****:* **:: **: :**:****:::* ***.. :*****.*:**::**** **: * ****:***.*.** .************. * ::.**:*:*.* *:* ::*.* :*** :********* *.* ***:****:*** ", "identical_positions": 110, "similar_positions": 46, "identity": "58.82%" }, { "cls_id": "homologset.agr.MGI:1860402", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D4A8C4-1", "uniprot_id": "D4A8C4_RAT", "id": "D4A8C4-1", "name": "Zinc finger protein 316", "aln": "MMAALHTAPDSPDTQLEPAEDGSECDAEPEEEEEEEE--EDDEQGREEEEVVVEEEVATQVQEAAGVEVEANSADTGGGDDGDDG-----DVEEVLAEEQTLSLGTQKRLSNGADAKSPALQGKALQASRLPPTTQGDDPEEEEEEE---DDEHFLTQG---LVTFEDVAVYFSLEEWERLDVDQRDLYRDVMQENYGILVSLGYPIPKPDLIFHLEQGEEPWVEDSPHPEEGDVVTGVYTGAWFWNDDLEDHEEEDDEDFLAEMAEEENEPPGLWSAAYGVGDVPGTWGPDDSDSVQTPEGWGPNPGSLGILAEEVEAKHFLSGRGPGENFLVPWAFP-AVAVPIGCPETTCDVCGKVFPHRSRLAKHQRYHAAVKPFGCEECGKGFVYRSHLAIHQRTHTGEKPFPCPDCGKRFVYKSHLVTHRRIHTGERPYRCVFCGAGFGRRSYLVTHQRTHTGERPYPCLHCGRSFSQSSALARHQAVHTADRPHCCPDCGQAFRLRADFQRHRRGGGCTEPSSGDGALTAPHEVGMAPNEVEMAIAAVATAEPEELESGLAEKNEEPKAGVADGDNEVEVRQDEQVVVAAAAEATVPDSKKDPEPDRRFREMGNGLAEGEGPSSHRFGFHFPMHPKSWLHPDGFPLLGFPEFSERLQTDGRHLPGPLGAPLSLQG-MGLACDPFRSAGPGARADSGLRAFAPAVGSLLSEPAPAALAEEESPWICSDCGKTFGRRAALAKHQRYHAGERPHRCADCGKSFVYGSHLARHRRTHTGERPFPCPECGARFARGSHLAAHVRGHTGEKPFVCGVCGAGFSRRAHLTAHGRAHTGERPYACAECGRRFGQSAALTRHQWAHAEEKPHRCPDCGKGFGHSSDFKRHRRTHTGEKPFRCADCGRGFAQRSNLAKHRRGHTGERPFPCPECGKRFSQRSVLVTHQRTHTGERPYLCSNCGRRFSQSSHLLTHMKTHRGQGGAPAQNTS-AKAQAPAKAIPPLPPSGSGSGAGTLLEFAGGTSFGSD-PAAFASPSGTYEESIL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q6PGE4-1", "uniprot_id": "ZF316_MOUSE", "id": "Q6PGE4-1", "name": "Zinc finger protein 316", "aln": "-MAALQSAPDSPATQLEPAEDGSECDADPEEEEEEEQ--QEEED-EEEEEEVVVEEVATPVQEVAEVEVEANSADNGGGDDDDDGGGGDDDVEEVLAEEQTLSLGTQERHSNGGHAKAPVLQGKALQTSRVSPTTQDEDVEEEEEEE---DEEHFLTQG---LVTFEDVAVYFSLEEWERLGVDQRDLYREVMQENYGILVSLGYPIPKPDLIFHLEQGEEPWVEDGPHPEEGDVVTGVYTGAWFWNDDIEDHEEEDDEDFLAEVAEEENEPPGLWSAAYGVGDVPGTWGPDDSDSVQTPEGWGPNPGSLGILAEEVEAKHFLSGREPGENFLVPWAFP-AVAVPIGCPETTCDVCGKVFPHRSRLAKHQRYHAAVKPFGCDECGKGFVYRSHLAIHQRTHTGEKPFPCPDCGKRFVYKSHLVTHRRIHTGERPYRCVFCGAGFGRRSYLVTHQRTHTGERPYPCLHCGRSFSQSSALARHQAVHTADRPHCCPDCGQAFRLRADFQRHRRSGGCTEPSSGDGARMAPHEVGMAPNEVEMAVAAVATVEPEELEAAPAET-EEPEAGVADGDTEAEARQDEQVVVAPAAEATVPDSKKDPEPDRRFREMGNGLAEGEGPSSHPFGFHFPMHPKSWLHPDGFPILGFPEFSERLQADGRHLPGPLGSPLSLQG-MGLACDPFRSVGPGAGVDGGLRAFPPAVRSLLSEPAPAALAEEESPWICSDCGKTFGRRAALAKHQRYHAGERPHRCADCGKSFVYGSHLARHRRTHTGERPFPCPECGARFARGSHLAAHVRGHTGEKPFVCGVCGAGFSRRAHLTAHGRAHTGERPYACAECGRRFGQSAALTRHQWAHAEEKPHRCPDCGKGFGHSSDFKRHRRTHTGEKPFRCADCGRGFAQRSNLAKHRRGHTGERPFPCPECGKRFSQRSVLVTHQRTHTGERPYLCSNCGRRFSQSSHLLTHMKTHRGPGSAPAHTSS-TKAQAPAKATPPLPPPGSGS--GTLLEFAGGTSFGSD-PAAFAGPSGSYEESIL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A6NFI3-1", "uniprot_id": "ZN316_HUMAN", "id": "A6NFI3-1", "name": "Zinc finger protein 316", "aln": "-MAALHTTPDSPAAQLERAEDGSECDPDQEEEEEEEEKGEEVQEVEEEEEEIVVEEEEEGVAEVVQDAQVEAVAEVEVEADVEEE-----DVKEVLAEEECPALGTQERLSRGGDAKSPVLQEKGLQASRAPATPRDEDLEEEEEEEEDEDEDDLLTAGCQELVTFEDVAVYFSLEEWERLEADQRGLYQEVMQENYGILVSLGYPIPKPDLIFRLEQGEEPWVPDSPRPEEGDIVTGVYTGAWFWTDDIEDHEEEDDEDFLAEVAEEENEPPGLWSAAYGVGDVPGTWGPDDSDSAQTPEGWGPDPGGLGVLADGSEAKPFLPGREPGANLLSPWAFPAAVAPPAGRPETTCDVCGKVFPHRSRLAKHQRYHAAVKPFGCEECGKGFVYRSHLAIHQRTHTGEKPFPCPDCGKRFVYKSHLVTHRRIHTGERPYRCAFCGAGFGRRSYLVTHQRTHTGERPYPCSHCGRSFSQSSALARHQAVHTADRPHCCPDCGQAFRLRADFQRHRRGGGCAEAG-GDGPRREPGET-------------AAAAGPEDTDPGPEGS----EVGEADGEAEAAAEERE----EAAVAAPTPSGKVDPAPERRFLELGNGLGEGEGPSSHPLGFHFPVHPKSWLHPDSFPILGLPDFRERLPVDGRPLPAPLGGPLSLVEGTGLACDPFGGGG-AAGGGGGLRAFGPAIGGLLAEPAPAALAEEESPWICSDCGKTFGRRAALAKHQRYHAGERPHRCADCGKSFVYGSHLARHRRTHTGERPFPCPECGARFARGSHLAAHVRGHTGEKPFVCGVCGAGFSRRAHLTAHGRAHTGERPYACGECGRRFGQSAALTRHQWAHAEEKPHRCPDCGKGFGHSSDFKRHRRTHTGEKPFRCADCGRGFAQRSNLAKHRRGHTGERPFPCPECGKRFSQRSVLVTHQRTHTGERPYACANCGRRFSQSSHLLTHMKTHRGATAAPGSGSAPAPAPKPEAAAKGPSSAGPGERGSALLEFAGGTSFGSEHQAAFAGPSGAYREGVL", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ****:::**** :*** ********.: *******: :: :: .**** :* ** * *.. *: * :: **:******: :****:* *.*..**:*.** *.**:** ..*.:.:* ******* *::.:** * ******************* .***.**::***********************:********* *.*:*****:***********.**:**************:*******************************.********:**.**:**: *** **.** ** *:* ***** *** * * *********************************:*******************************************************.*************************** *********************************************.***:*.. ***. * *. .*:. **: :.. . :.* ***: *. ..: * .*. *..*..* ** *:*** *:****.******** :*****:*********.**:**:*:* *** .*** **.***.**** ******* . * .* ..***** **: .**:********************************************************************************************************************************.************************************************************************************************************* *:********************* .**. :: : * * * ...*.*. .:************: ****.***:*.*.:*", "identical_positions": 773, "similar_positions": 125, "identity": "74.83%" }, { "cls_id": "homologset.agr.MGI:1860403", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I6AJR9-1", "uniprot_id": "A0A8I6AJR9_RAT", "id": "A0A8I6AJR9-1", "name": "Elongin-B", "aln": "MMKTPPQHQQQVWCIKPEAATGMEVFLMIRRKKTTIFAEAQESSTVLELKRIVQGILKRPPEEQLLFKDDQLLDESKTLRDCGFTSQIAKAQDPATVALVFR-EDASEGVQIHPYSTPL-LPSVMKTGTDSLSDEIKS------GLDSLSDEIKSGLDSVSSMEQLVL---------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "D3ZNR1-1", "uniprot_id": "D3ZNR1_RAT", "id": "D3ZNR1-1", "name": "Elongin-B", "aln": "----------------------MEVFLMIRRKKTTIFIEAQELTTVLELKRIVQGILKRPPEEQLLFKDDQLLDESKTLRDCGFTSRVAKAQDPATVGLVFR-EDASEGLQIHPYSTPL-LPSVMKTGTDSLE--------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q15370-1", "uniprot_id": "ELOB_HUMAN", "id": "Q15370-1", "name": "Elongin-B", "aln": "----------------------MDVFLMIRRHKTTIFTDAKESSTVFELKRIVEGILKRPPDEQRLYKDDQLLDDGKTLGECGFTSQTARPQAPATVGLAFRADDTFEALCIEPFSSPPELPDVMK------------------PQDSGSSANEQAVQ-------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A6PWE0-1", "uniprot_id": "A6PWE0_MOUSE", "id": "A6PWE0-1", "name": "Elongin-B", "aln": "----------------------MDVFLMIRYKKTTILTDAKESSTVLALKRIIEGIMKRPPEEQLLFKDNQLLDEMKTLRECGFTSQVARPEAPATVGLAFRTGDVFEGLEIHPYSPPLDLLDLLKASQNEANEPLFDEDPANEPLSNEDPANEQFFDDEPPNQQFFHNLPNQFFDDDPMCNH", "tax_id": 10090, "tax_name": "Mouse" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *:****** :****: :*:* :**: ****::**:****:** *:**:****: *** :*****: *:.: ****.*.** *. *.: *.*:*.* * .::* ", "identical_positions": 58, "similar_positions": 30, "identity": "31.69%" }, { "cls_id": "homologset.agr.MGI:1860417", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q568Z9-1", "uniprot_id": "PHYIP_RAT", "id": "Q568Z9-1", "name": "Phytanoyl-CoA hydroxylase-interacting protein", "aln": "MELLSTPHSIEINNITCDSFRISWAMEDSDLERVTHYFIDLNKKENKNSNKFKHRDVPTKLVAKAVPLPMTVRGHWFLSPRTEYSVAVQTAVKQSDGEYLVSGWSETVEFCTGDYAKEHLAQLQEKAEQIAGRMLRFSVFYRNHHKEYFQHARTHCGNVLQPYLKDNSGSHGSPTSGMLHGVFFSCNTEFNTGQPPQDSPYGRWRFQIPAQRLFNPSTNLYFADFYCMYTAYHYAILVLAPKGSLGDRFCRDRLPLLDIACNKFLTCSVEDGELIFRHAQDLILEIIYTEPVDLSLGTLGEISGHQLMSLSTADAKKDPSCKTCNISVGR", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8K0S0-1", "uniprot_id": "PHYIP_MOUSE", "id": "Q8K0S0-1", "name": "Phytanoyl-CoA hydroxylase-interacting protein", "aln": "MELLSTPHSIEINNITCDSFRISWAMEDSDLERVTHYFIDLNKKENKNSNKFKHRDVPTKLVAKAVPLPMTVRGHWFLSPRTEYSVAVQTAVKQSDGEYLVSGWSETVEFCTGDYAKEHLAQLQEKAEQIAGRMLRFSVFYRNHHKEYFQHARTHCGNVLQPYLKDNSGSHGSPTSGMLHGVFFSCNTEFNTGQPPQDSPYGRWRFQIPAQRLFNPSTNLYFADFYCMYTAYHYAILVLAPKGSLGDRFCRDRLPLLDIACNKFLTCSVEDGELIFRHAQDLILEIIYTEPVDLSLGTLGEISGHQLMSLSTADAKKDPSCKTCNISVGR", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q92561-1", "uniprot_id": "PHYIP_HUMAN", "id": "Q92561-1", "name": "Phytanoyl-CoA hydroxylase-interacting protein", "aln": "MELLSTPHSIEINNITCDSFRISWAMEDSDLERVTHYFIDLNKKENKNSNKFKHRDVPTKLVAKAVPLPMTVRGHWFLSPRTEYSVAVQTAVKQSDGEYLVSGWSETVEFCTGDYAKEHLAQLQEKAEQIAGRMLRFSVFYRNHHKEYFQHARTHCGNMLQPYLKDNSGSHGSPTSGMLHGVFFSCNTEFNTGQPPQDSPYGRWRFQIPAQRLFNPSTNLYFADFYCMYTAYHYAILVLAPKGSLGDRFCRDRLPLLDIACNKFLTCSVEDGELVFRHAQDLILEIIYTEPVDLSLGTLGEISGHQLMSLSTADAKKDPSCKTCNISVGR", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "**************************************************************************************************************************************************************:*******************************************************************************************************************:*******************************************************", "identical_positions": 328, "similar_positions": 2, "identity": "99.39%" }, { "cls_id": "homologset.agr.MGI:1860418", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P81799-1", "uniprot_id": "NAGK_RAT", "id": "P81799-1", "name": "N-acetyl-D-glucosamine kinase", "aln": "MAALYGGVEGGGTRSKVLLLSEDGQILAEADGLSTNHWLIGTGTCVERINEMVDRAKRKAGVDPLVPLRSLGLSLSGGEQEDAVRLLMEELRDRFPYLSESYFITTDAAGSIATATPDGGIVLISGTGSNCRLINPDGSESGCGGWGHMMGDEGSAYWIAHQAVKIVFDSIDNLEAAPHDIGHVKQAMFNYFQVPDRLGILTHLYRDFDKSKFAGFCQKIAEGAQQGDPLSRFIFRKAGEMLGRHVVAVLPEIDPVLFQGELGLPILCVGSVWKSWELLKEGFLLALTQGREQQAQNSFSSFTLMKLRHSSALGGASLGARHIGHHLPMDYSVNAIAFYSYTF-------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9QZ08-1", "uniprot_id": "NAGK_MOUSE", "id": "Q9QZ08-1", "name": "N-acetyl-D-glucosamine kinase", "aln": "MAALYGGVEGGGTRSKVLLLSEDGQILAEADGLSTNHWLIGTDQCVERINEMVDRAKQKAGVDPLVPLRSLGLSLSGGEQEDAVRLLIEELRHRFPNLSENYLITTDAAGSIATATPDGGIVLISGTGSNCRLINPDGSESGCGGWGHMMGDEGSAYWIAHQAVKIVFDSIDNLEAAPHDIGHVKQAMFDYFQVPDRLGILTHLYRDFDKCKFAGFCQKIAEGAHQGDPLSRYIFRKAGEMLGRHVVAVLPEIDPVLFQGELGLPILCVGSVWKSWELLKEGFLLALTLGREQQAQNSFSSFTLMKLRHSSALGGASLGARHIGYHLPMDYSINAIAFYSYTF-------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9UJ70-1", "uniprot_id": "NAGK_HUMAN", "id": "Q9UJ70-1", "name": "N-acetyl-D-glucosamine kinase", "aln": "MAAIYGGVEGGGTRSEVLLVSEDGKILAEADGLSTNHWLIGTDKCVERINEMVNRAKRKAGVDPLVPLRSLGLSLSGGDQEDAGRILIEELRDRFPYLSESYLITTDAAGSIATATPDGGVVLISGTGSNCRLINPDGSESGCGGWGHMMGDEGSAYWIAHQAVKIVFDSIDNLEAAPHDIGYVKQAMFHYFQVPDRLGILTHLYRDFDKCRFAGFCRKIAEGAQQGDPLSRYIFRKAGEMLGRHIVAVLPEIDPVLFQGKIGLPILCVGSVWKSWELLKEGFLLALTQGREIQAQNFFSSFTLMKLRHSSALGGASLGARHIGHLLPMDYSANAIAFYSYTFS------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A0R4IUJ5-1", "uniprot_id": "A0A0R4IUJ5_DANRE", "id": "A0A0R4IUJ5-1", "name": "N-acetyl-D-glucosamine kinase", "aln": "MSAVYGGVEGGGTHSKAVLVSAEGDILAETDGPCTNHWLVGVDNCISGINEMVQSAKIKAGLDPDTPICSLGMSLSGGEQKAAIQKLIDDMHERYPKLSQSYFITTDAIGAMATASDYGGIVVISGTGSNCKLVNPDGTQIGCGGWGHMMGDEGSAYWISHLAVKTVFDARDNLVTSPHDITYVKKAMEDYFQVSDLMGMLPHLYRNFQKSHFAGFCRKLAEGGNAGDALCQHVFREAGKVLAQHIVAVLPEVHQDLFRGELGLPVLCVGSVWRSWELMKSGFTQVLSQAQS-HDYSHFRKYSLLTLRQSSALGGAKMGAKNIGTTLPLDYSANVNMFFSHTFTQ-----------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VF86-1", "uniprot_id": "Q9VF86_DROME", "id": "Q9VF86-1", "name": "N-acetyl-D-glucosamine kinase", "aln": "-MKYFGGVEGGATHSRLVICDESGQSVGATSGLGTNHWGIGIPECARRIADMVERAKEEAGIPKETPLTSLGLSLSGCEQEATNRELEQELRTTFPGLAQNYAVSSDTMGSMYTASSIGGMVLISGTGSNCLLRNPDGSTSNCGGWGNFLGDEGSAWYISYRAVKVVFDHMDNFEQSAAPVEKTWSLIKEHFSLETRLDMLPHCYAKFDKPFFANLCKKLSQNAENGDELARSLFREAGVHLARMILALLPNVHQDLVK-SGDLSVVCVGSVWSSWDLLQEAFISELAKTTIDFDLK------LVRITKSSAYGACYLGADSADFDLPRNYADNVTVLYTYTDPRKKAKATNGCNC", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :******.*:*. :: . .*. :. :.* **** :* * * :**: ** :**: .*: ***:**** :*: : : * :::: :* *::.* :::*: *:: **: **:*:******** * ****: .*****:::******::*:: *** *** **: :. : . . : .:*.: :.:*.* * .*:* **.:*:*:::... ** *.: :**:** *.: ::*:**::. *.: . .*.::****** **:*::..* *: . *: : :*** *.. :** . ** :*: *. ::::* ", "identical_positions": 122, "similar_positions": 117, "identity": "34.27%" }, { "cls_id": "homologset.agr.MGI:1860425", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q5BJQ1-1", "uniprot_id": "Q5BJQ1_RAT", "id": "Q5BJQ1-1", "name": "Claudin", "aln": "MASTAVQLLGFLLSFLGMVGTLITTILPHWRRTAHVGTNILTAVSYLKGLWMECVWHSTGIYQCQIYRSLLALPRDLQAARALMVISCLLSGMACACAVVGMKCTRCAKGTPAKTTFAVLGGALFLLAGLLCMVAVSWTTNDVVQNFYNPLLPSGMKFEIGQALYLGFISSSLSLIGGTLLCLSCQDEG-----PYRPYQPQSRAGATTTATAPAYRPPAAYKD------NRAPSVTSAAHS--------------------GYRLNDYV", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9Z0S3-1", "uniprot_id": "CLD14_MOUSE", "id": "Q9Z0S3-1", "name": "Claudin-14", "aln": "MASTAVQLLGFLLSFLGMVGTLITTILPHWRRTAHVGTNILTAVSYLKGLWMECVWHSTGIYQCQIYRSLLALPRDLQAARALMVISCLLSGMACACAVVGMKCTRCAKGTPAKTTFAVLGGALFLLAGLLCMVAVSWTTNDVVQNFYNPLLPSGMKFEIGQALYLGFISSSLSLIGGTLLCLSCQDEA-----PYRPYPPQSRAGATTTATAPAYRPPAAYKD------NRAPSVTSAAHS--------------------GYRLNDYV", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O95500-1", "uniprot_id": "CLD14_HUMAN", "id": "O95500-1", "name": "Claudin-14", "aln": "MASTAVQLLGFLLSFLGMVGTLITTILPHWRRTAHVGTNILTAVSYLKGLWMECVWHSTGIYQCQIYRSLLALPQDLQAARALMVISCLLSGIACACAVIGMKCTRCAKGTPAKTTFAILGGTLFILAGLLCMVAVSWTTNDVVQNFYNPLLPSGMKFEIGQALYLGFISSSLSLIGGTLLCLSCQDEA-----PYRPYQAPPRATTTTANTAPAYQPPAAYKD------NRAPSVTSATHS--------------------GYRLNDYV", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M2BHN3-1", "uniprot_id": "A0A8M2BHN3_DANRE", "id": "A0A8M2BHN3-1", "name": "", "aln": "MAILALELMGFFFGLIGMLGTLVATLLPYWATSAHVGPNIVTAVVSMKGLWMECVYQSTGAFQCETYNTLLGLTVDLQAARAMMVMSSIFSVMACAVSTVGMQCTVCMDGSSVKTKVAGVGGSMFLLAGLLSLIPVAWKTHEVVQTFYMPNMPASLKFEIGDCLYVGLASSLLSMLGGGLLSASCCDDIDGNRGSRRHYPYPERNALRGPSHSMTYQPAALHSTTNPNITNKTQTLNSHTSSGTHSIQAQDSRKMTRQNTAAGYDVTGYV", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "** *::*:**::.::**:***::*:**:* :****.**:*** :********::*** :**: *.:**.*. *******:**:*.::* :*** :.:**:** * .*:..**..* :**::*:*****.::.*:*.*::***.** * :*:.:*****:.**:*: ** **::** **. ** *: . * * * . : :*:*.* :. *:: ::.* : * ** :..**", "identical_positions": 114, "similar_positions": 83, "identity": "42.22%" }, { "cls_id": "homologset.agr.MGI:1860433", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9JHG1-1", "uniprot_id": "PIGP_MOUSE", "id": "Q9JHG1-1", "name": "Phosphatidylinositol N-acetylglucosaminyltransferase subunit P", "aln": "------------------------------------------------------------------------------------------------------MVENSPSPLPERAIYGFVLFLSSQFGFILYLVWAFVPESWLNSLGLTYWPQKYWAVALPVYLLITVVIGYV-LLFGINMMSTSPLDSIHTITDNYAKNQQ-------RKNYQEDAIPALRDVPISEVNKMFFLGAKELNT--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0ABK0LBB8-1", "uniprot_id": "A0ABK0LBB8_RAT", "id": "A0ABK0LBB8-1", "name": "", "aln": "MAAIKHPAITSVSHRLVTGISTYCGNNLQTEGCLETTSFWKRHRAGVPAHPRLHFGPLRPPRLSPPHYGMAAQALMTSPALLSSSPCAGVGQGCRLSKATGKMVENSPSPLPERAIYGFVLFLSSQFGFILYLVWAFVPESWLNSLGLTYWPQKYWAVALPVYLLITVVIGYV-LLFGINMMSTSPLDSIHTITDNYAKNQQ-------RKSYQEDAIPALRDIPISEVNRMFFLDAKELNT--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P57054-1", "uniprot_id": "PIGP_HUMAN", "id": "P57054-1", "name": "Phosphatidylinositol N-acetylglucosaminyltransferase subunit P", "aln": "---------------------------------------------------------------------MVPR---------STSLTLIVFLFHRLSKAPGKMVENSPSPLPERAIYGFVLFLSSQFGFILYLVWAFIPESWLNSLGLTYWPQKYWAVALPVYLLIAIVIGYV-LLFGINMMSTSPLDSIHTITDNYAKNQQ-------QKKYQEEAIPALRDISISEVNQMFFLAAKELYTKN", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A2R8Q1D2-1", "uniprot_id": "A0A2R8Q1D2_DANRE", "id": "A0A2R8Q1D2-1", "name": "Phosphatidylinositol N-acetylglucosaminyltransferase subunit P", "aln": "----------------------------------------------------------------------------------------------------MVMVENSPSPLPERAIYGFVLFLGAQLGFLLYVVWAFVPDSWLHAAGLTYWPQKYWALAGPIYLLVALSTCFV-LLFGVNMMNTAPLASVDNITDAYGRSQR-------VDEDQPGAIPRLRDVSVSEMSRLFYL---------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q04082-1", "uniprot_id": "GPI19_YEAST", "id": "Q04082-1", "name": "Phosphatidylinositol N-acetylglucosaminyltransferase subunit GPI19", "aln": "------------------------------------------------------------------------------------------------------MYTKEYYWFSQYMIITSTLVLTIIWSILPSSLGEAAPKQFINTL-LDIFPQRRWIITLESIMLMGMLCTYIGLLMYNEDTLTPPLDSLSTVTDAGGQLVIEDDPDVFVKKWAFKETSGIYDLSLMDACQLLYLYDNDHTST-", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * :. :.: * .*.* .:: : *..:::: * :**: * :: :*: : :: **: : *.** *: .:** .: .. . : *:.: : ::::* ", "identical_positions": 20, "similar_positions": 46, "identity": "8.2%" }, { "cls_id": "homologset.agr.MGI:1860437", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O88998-1", "uniprot_id": "NOE1_MOUSE", "id": "O88998-1", "name": "Noelin", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSVPLLKIG--------VVLSTMAMITNWMSQTLPSLVGLNTTRLSAASGGTLDRSTGVLPTNPEESWQVYSSAQDSEGR-----CICTVVAPQQTMCSRDARTKQLRQLLEKVQNMSQSIEVLDRRTQRDLQYVEKMENQMKGLETKFKQVEESHKQHLARQFKAIKAKMDELRPLIPVLEEYKADAK-------------------------------------------------------LVLQFKEEVQNLTSVLNELQEEIGAYDYDELQS-----------RVSNLEERLRACMQKLACGKLTG--------------ISDPVTVKTSGSRFGSWMTDPLAPEGDNRVWYMDGYHNNRFVREYKSMVDFMNTDNFTSHRLPHPWSGTGQVVYNGSIYFNKFQSHIIIRFDLKTEAILKTRSLDYAGYNNMYHYAWGGHSDIDLMVDENGLWAVYATNQNAGNIVISKLDPVSLQILQTWNTSYPKRSAGEAFIICGTLYVTN-GYSGGTKVHYAYQTNASTYEYIDIPFQNKYSHISMLDYNPKDRALYAWNNGHQTLYNVTLFHVIRSDEL-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q62609-1", "uniprot_id": "NOE1_RAT", "id": "Q62609-1", "name": "Noelin", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSVPLLKIG--------VVLSTMAMITNWMSQTLPSLVGLNTTRLSAASGGTLDRSTGVLPTNPEESWQVYSSAQDSEGR-----CICTVVAPQQTMCSRDARTKQLRQLLEKVQNMSQSIEVLDRRTQRDLQYVEKMENQMKGLESKFRQVEESHKQHLARQFKAIKAKMDELRPLIPVLEEYKADAK-------------------------------------------------------LVLQFKEEVQNLTSVLNELQEEIGAYDYDELQS-----------RVSNLEERLRACMQKLACGKLTG--------------ISDPVTVKTSGSRFGSWMTDPLAPEGDNRVWYMDGYHNNRFVREYKSMVDFMNTDNFTSHRLPHPWSGTGQVVYNGSIYFNKFQSHIIIRFDLKTETILKTRSLDYAGYNNMYHYAWGGHSDIDLMVDENGLWAVYATNQNAGNIVISKLDPVSLQILQTWNTSYPKRSAGEAFIICGTLYVTN-GYSGGTKVHYAYQTNASTYEYIDIPFQNKYSHISMLDYNPKDRALYAWNNGHQTLYNVTLFHVIRSDEL-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q99784-1", "uniprot_id": "NOE1_HUMAN", "id": "Q99784-1", "name": "Noelin", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSVPLLKIG--------VVLSTMAMITNWMSQTLPSLVGLNTTKLSAAGGGTLDRSTGVLPTNPEESWQVYSSAQDSEGR-----CICTVVAPQQTMCSRDARTKQLRQLLEKVQNMSQSIEVLDRRTQRDLQYVEKMENQMKGLESKFKQVEESHKQHLARQFKAIKAKMDELRPLIPVLEEYKADAK-------------------------------------------------------LVLQFKEEVQNLTSVLNELQEEIGAYDYDELQS-----------RVSNLEERLRACMQKLACGKLTG--------------ISDPVTVKTSGSRFGSWMTDPLAPEGDNRVWYMDGYHNNRFVREYKSMVDFMNTDNFTSHRLPHPWSGTGQVVYNGSIYFNKFQSHIIIRFDLKTETILKTRSLDYAGYNNMYHYAWGGHSDIDLMVDESGLWAVYATNQNAGNIVVSRLDPVSLQTLQTWNTSYPKRSAGEAFIICGTLYVTN-GYSGGTKVHYAYQTNASTYEYIDIPFQNKYSHISMLDYNPKDRALYAWNNGHQILYNVTLFHVIRSDEL-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "B7ZD15-1", "uniprot_id": "B7ZD15_DANRE", "id": "B7ZD15-1", "name": "", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSVPLLKIG--------VVLSTMAMITNWMSQTLPSLVGLNTTKLTAAQGGYPDRSIGVLPANPEESWQVYSSAQDSEGR-----CVCTVVAPQQTMCSRDARTKQLRQLLEKVQNMTQSIQVLDQRTQRDLQYVVKMEDQLRGLETKFRQVEENHKQNIAKQYKAIKAKMAELRPLIPVLEEYKADAR-------------------------------------------------------LVQQFKEEVQNLTASLGLLQQEMGAYDYDDLHS-----------RVVSLEERLRACMQKLACGKLTG--------------ISDAITIKTSGSRFGSWMTDPLAPEGDTRVWYMDGYHNNRFVREYKSMADFMTSDNFTSHRLPHPWSGTGQVVYNGSIYFNKFQSNMIIKFDFKTSTMSKSQRLDNAGFSNTYHYAWGGHSDIDLMVDEGGLWAVYATNQNAGNIVISKLHPITLHIIQSWTTNHPRRSAGESFMICGTLYVTN-GYSGGTKVYYAYHTNSSTYEYIDIVLQNKYSHISMLDYNPRDRALYAWNNGHQVLYNVTLFHVIRSEQL-", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A2AWU1-1", "uniprot_id": "A2AWU1_DANRE", "id": "A2AWU1-1", "name": "", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSVPLLKIG--------VVLSTMAMITNWMSQTLPSLVGLNSTKLSVAPPGVPDRSTGVLPANPEESWQVYSSAQDSEGR-----CVCTVVAPQQTMCSRDARTKQLRQLLEKVQNMTQSIQNLDQRTQKDLQYVQRMEVQLRGLETKFKQVEESHKQNIAKQYKAIKAKMEELRPMIPVLEEYKADAK-------------------------------------------------------LVMQFKEEVKNLTSVLSELQEEIGAFDYEELHN-----------RVSNLEERLRACMQKLACGKLTG--------------ISDAITIKTSGSRYGSWMTDPLAPDGDTRVWYMDGYHNNRFVREYKSMADFMYSDNFTSHRLPHPWSGTGQVVYNGSIYFNKFQSNTIIKFDFKTATISKSGQLDYAGFNNRYHYSWGGHSDIDLMVDEGGLWAIYATNQNAGNIVISKLNPATLQIVKSYTTNHPKRSAGEAFMICGTLYVTN-GYSGGTKVYYAFHTNSSTYEYIDIPLQNKYSHISMLDYNPRDRALYAWNNGHQVLYNVTLFHVIRSEEL-", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VWZ7-1", "uniprot_id": "Q9VWZ7_DROME", "id": "Q9VWZ7-1", "name": "Colmedin", "aln": "MFLAVNQSLQNTSKKKRKRRTAEDDPQEDSGEGTPPVRPLEPSASSDQLVGVGNGATCRVCKCPGRQSLTLVYIYLGALTLILASLSIVFYTHTQDVESLSQVEDNYSSKSFRVQFQAELMRSEEELRRLVNRIIEEEQELVGSTTASSTTQSRDPLKNERKFTDNLISHTTRPTGKRMRRDIASSAPASMHADPLIEFFNPNHRKVLEEQDTEIRKRTGQKGAAPGGDEWIYLNTYCRVPEKIITGFCKGTQDYCPPAPQGPTGEVGPKGPPGNPGLPGIPGPKGNRGDVGLPGAPGVDGVGHLGPAGPRGPKGDAGATGRAGLDGRDGVPGEPGLDGVPGRAGADGKNGLPGRDGKDGLHGKDGKDGLSITGPKGAQGPPGERGLKGIAGPRGRPGKPGTNGIPGVPGINAWKLQYPNGSSSNDLLIPPSITDIQVPDFQRTVIVEEGRSLNLSCTATGTPTPQVEWRREDGRTINVNGVEMASISGQFLRFTNITRHQMAAYTCFANNGIAPVANATYLVEVQFAPMISVYRQMIYAEYQSSATLECLVEAFPEAIRYWERAYDGKILDPSDKYGIESYPEGFKTTMRLTISNLRKDDFGYYHCVARNELNATMVNFEIAPQDPNSETPYVGNNMKVYGQRPPESECPVCDQCPDPSLYQCKDSILNNFEIQATGNLSYPGLPKRPKTCYLYAVGKPVFHKVVNEKFGSWLRDPSPDSDREKTFVTNENDPYNLFEFTTRIQYRMNSIPRRKYEIQEGFHGNAHVVFNGSFYYQQRNSDLVVKLDLTSLKKITT-QLPYAGVAAANRLYTTDYNYMDFNVDEVGLWVIYST-YNSNNTLVAKLDAETLKMQYNFNITLDHHQFGEMFIVCGNLYAIDSGTDKNTQIRYVVDLYKGKLLNTNLPFSNPFSHTTTVGYNPLTVELYSWDKGNALTYPIRYNEQRLISDNS", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :: * * : .. . : :: :*.: *:*: :* . . : . . : :. :. .*** * .* ... *. *: . : :* .. * :. : :: *. : : : . ** .. :: : * *: . .: ::* : : : :*: :: .: : ::: .:. .. : . :: : :: * *:*: :...: *. ..::***: ** . .. :.: : . .:.. . : * : .:.: . : *..:**:***:*::: :*. ::::*:.: .: * ** : .:. :*: *** ***.:*:* *:.* ::::*.. :*: .:. . ::. ** *::**.**. : * . .*:: *. . .. :: :.* :** : :.*** **:*::*: * : . .: ", "identical_positions": 78, "similar_positions": 191, "identity": "8.2%" }, { "cls_id": "homologset.agr.MGI:1860440", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q6IE75-1", "uniprot_id": "BACE2_RAT", "id": "Q6IE75-1", "name": "Beta-secretase 2", "aln": "MGALLRALLLPLLAQWLLRAVPVLAPAPFTLPLQVAGAANHRASTVPGLGTPELPRADGLALALEPARAT----ANFLAMVDNLQGDSGRGYYLEMLIGTPPQKVRILVDTGSSNFAVAGAPHSYIDTYFDSESSSTYHSKGFEVTVKYTQGSWTGFVGEDLVTIPKGFNSSFLVNIATIFESENFFLPGIKWNGILGLAYAALAKPSSSLETFFDSLVAQAKIPDIFSMQMCGAGLPVAGSG-TNGGSLVLGGIEPSLYKGDIWYTPIKEEWYYQIEILKLEIGGQSLNLDCREYNADKAIVDSGTTLLRLPQKVFDAVVEAVARTSLIPEFSDGFWTGAQLACWTNSETPWAYFPKISIYLRDENASRSFRITILPQLYIQPMMGAGFNYECYRFGISSSTNALVIGATVMEGFYVVFDRAQRRVGFAVSPCAEIAGTTVSEISGPFSTEDIASNCVPAQALNEPILWIVSYALMSVCGAILLVLILLLLFPLHCRHAPRDPEVVNDESSLVRHRWK", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9JL18-1", "uniprot_id": "BACE2_MOUSE", "id": "Q9JL18-1", "name": "Beta-secretase 2", "aln": "MGALLRALLLLVLAQWLLSAVPALAPAPFTLPLQVAGATNHRASAVPGLGTPELPRADGLALALEPVRAT----ANFLAMVDNLQGDSGRGYYLEMLIGTPPQKVQILVDTGSSNFAVAGAPHSYIDTYFDSESSSTYHSKGFDVTVKYTQGSWTGFVGEDLVTIPKGFNSSFLVNIATIFESENFFLPGIKWNGILGLAYAALAKPSSSLETFFDSLVAQAKIPDIFSMQMCGAGLPVAGSG-TNGGSLVLGGIEPSLYKGDIWYTPIKEEWYYQIEILKLEIGGQNLNLDCREYNADKAIVDSGTTLLRLPQKVFDAVVEAVARTSLIPEFSDGFWTGAQLACWTNSETPWAYFPKISIYLRDENASRSFRITILPQLYIQPMMGAGFNYECYRFGISSSTNALVIGATVMEGFYVVFDRAQRRVGFAVSPCAEIEGTTVSEISGPFSTEDIASNCVPAQALNEPILWIVSYALMSVCGAILLVLILLLLLPLHCRHAPRDPEVVNDESSLVRHRWK", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9Y5Z0-1", "uniprot_id": "BACE2_HUMAN", "id": "Q9Y5Z0-1", "name": "Beta-secretase 2", "aln": "MGALARALLLPLLAQWLLRAAPELAPAPFTLPLRVAAATNRVVAPTPGPGTPAERHADGLALALEPALASPAGAANFLAMVDNLQGDSGRGYYLEMLIGTPPQKLQILVDTGSSNFAVAGTPHSYIDTYFDTERSSTYRSKGFDVTVKYTQGSWTGFVGEDLVTIPKGFNTSFLVNIATIFESENFFLPGIKWNGILGLAYATLAKPSSSLETFFDSLVTQANIPNVFSMQMCGAGLPVAGSG-TNGGSLVLGGIEPSLYKGDIWYTPIKEEWYYQIEILKLEIGGQSLNLDCREYNADKAIVDSGTTLLRLPQKVFDAVVEAVARASLIPEFSDGFWTGSQLACWTNSETPWSYFPKISIYLRDENSSRSFRITILPQLYIQPMMGAGLNYECYRFGISPSTNALVIGATVMEGFYVIFDRAQKRVGFAASPCAEIAGAAVSEISGPFSTEDVASNCVPAQSLSEPILWIVSYALMSVCGAILLVLIVLLLLPFRCQRRPRDPEVVNDESSLVRHRWK", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M3AH32-1", "uniprot_id": "A0A8M3AH32_DANRE", "id": "A0A8M3AH32-1", "name": "", "aln": "--MRLYGLLLLSLTFWKSHSVFKIPLNIFAGKFNASVQLDLRP-----LQKNEAAAKSGLSLASDPAGIV-----NFLDMINNLKGDSGRGYYMQMIIGTPGQTLNILVDTGSSNFAVAAAAHPYITHYFNRALSSTYQSTERAVAVKYTQGEWEGELGTDLITIPEGPSGAITINIAAILTSEGFFLPGINWQGILGLAYPLLARPDPSVEPFFNSVVRQTGIPDVFSLQMCGAGVPASTTGDPAGGSLIMGGVEPTLHRGPIWYTPVLEEWYYQVEVLKLEVGDQNLNLDCKEYNSDKAIVDSGTTLLRLPANVFTAVVDTIMQTSLIDDFSAGFFDGTKLACWMRGESPWRFFPKVSIYLRGTNTSQSFRITILPQLYIQPVTDIDGTLDCFRFGISPSANGLVIGATVMEGFYVIFDRAQKRVGFAVSTCAENGGVPFAEIAGPFLAEGVASDCTSGMTLREPVMWVIAYTLMGVCAVVLIILLVLLILP--CRR-HRDDEIT-DESSLVRHRIK", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .*** *: * :. :. *: :..: : . .**:** :*. *** *::**:********::*:**** *.:.*************.:.*.** **: ****:*. *:******.* * :* **:***:* . :: :***:*: **.******:*:*******. **:*..*:*.**:*:* *: **::**:******:*.: :* . ****::**:**:*::* *****: ******:*:****:*.*.*****:***:*************** :** ***::: ::*** :** **: *::**** ..*:** :***:*****. *:*:**************: . . . :*:*****.*:*.*************:*****:*****.*.*** *...:**:*** :*.:**:*... :* **::*:::*:**.**..:*::*::**::* *:: ** *:. ********* *", "identical_positions": 280, "similar_positions": 142, "identity": "53.95%" }, { "cls_id": "homologset.agr.MGI:1860443", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q08602-1", "uniprot_id": "PGTA_RAT", "id": "Q08602-1", "name": "Geranylgeranyl transferase type-2 subunit alpha", "aln": "MHGRLKVKTSEEQAEAKRLEREQKLKLYQSATQAVFQKRQAGELDESVLELTSQILGANPDFATLWNCRREVLQHLETEKSPEES--------------------------------AALVKAELGFLESCLRVNPKSYGTWHHRCWLLSRLPEPN---WARELELCARFLEADERNFHCWDYRRFVAA-----QAAVAPAEELAFTDSLITRNFSNYSSWHYRSCLLPQLHPQ------------PDSGPQ---GRLPENVLLKELELVQNAFFTDPNDQSAWFYHRWLLGRAEPHDVLCCVHVSREEACLSVCFSRPLTVGSRMGTLLLMVDEAPLSVEWRTPDGRNRPSHVWLCDLPAASLNDQLPQHTFRVIWTGSDSQKECVLLKDRPECWCRDSATDEQLFRCELSVEKSTVLQSELESCKELQELEPENKWCLLTIILLMRALDP--LLYEKETLQYFSTLKAVDPMRAAYLDDLRSKFLLENSVLKMEYADVR--VLHLAHKDLTVLCHLEQLLLVTHLDLSHNRLRALPPALAALRCLEVLQASDNALENVDGVANLPRLQELLLCNNRLQQSAAIQPLVSCPRLVLLNLQGNSLCQEEGIQERLAEMLPSVSSILT", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9JHK4-1", "uniprot_id": "PGTA_MOUSE", "id": "Q9JHK4-1", "name": "Geranylgeranyl transferase type-2 subunit alpha", "aln": "MHGRLKVKTSEEQAEAKRLEREQKLKLYQSATQAVFQKREAGELDESVLELTSQILGANPDFATLWNCRREVLQQLETQKSPEEL--------------------------------AALVKAELGFLESCLRVNPKSYGTWHHRCWLLSRLPEPN---WARELELCARFLEADERNFHCWDYRRFVAA-----QAAVAPAEELAFTDSLITRNFSNYSSWHYRSCLLPQLHPQ------------PDSGPQ---GRLPENVLLRELELVQNAFFTDPNDQSAWFYHRWLLGRAEPHDVLCCLHVSREEACLSVCFSRPLIVGSKMGTLLLTVDEAPLSVEWRTPDGRNRPSHVWLCDLPAASLNDHLPQHTFRVIWTGSDTQKECVLLKGHQECWCRDSATDEQLFRCELSVEKSTVLQSELESCKELQELEPENKWCLLTIILLMRALDP--LLYEKETLEYFSTLKAVDPMRAAYLDDLRSKFLVENSVLKMEYADVR--VLHLAHKDLTVLCHLEQLLLVTHLDLSHNRLRALPPALAALRCLEVLQASDNVLENLDGVANLPRLRELLLCNNRLQQSAALQTLASCPRLVFLNLQGNSLCQEEGIRERLAEMLPSVSSILT", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q92696-1", "uniprot_id": "PGTA_HUMAN", "id": "Q92696-1", "name": "Geranylgeranyl transferase type-2 subunit alpha", "aln": "MHGRLKVKTSEEQAEAKRLEREQKLKLYQSATQAVFQKRQAGELDESVLELTSQILGANPDFATLWNCRREVLQQLETQKSPEEL--------------------------------AALVKAELGFLESCLRVNPKSYGTWHHRCWLLGRLPEPN---WTRELELCARFLEVDERNFHCWDYRRFVAT-----QAAVPPAEELAFTDSLITRNFSNYSSWHYRSCLLPQLHPQ------------PDSGPQ---GRLPEDVLLKELELVQNAFFTDPNDQSAWFYHRWLLGRADPQDALRCLHVSRDEACLTVSFSRPLLVGSRMEILLLMVDDSPLIVEWRTPDGRNRPSHVWLCDLPAASLNDQLPQHTFRVIWTAGDVQKECVLLKGRQEGWCRDSTTDEQLFRCELSVEKSTVLQSELESCKELQELEPENKWCLLTIILLMRALDP--LLYEKETLQYFQTLKAVDPMRATYLDDLRSKFLLENSVLKMEYAEVR--VLHLAHKDLTVLCHLEQLLLVTHLDLSHNRLRTLPPALAALRCLEVLQASDNAIESLDGVTNLPRLQELLLCNNRLQQPAVLQPLASCPRLVLLNLQGNPLCQAVGILEQLAELLPSVSSVLT", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1NBE9-1", "uniprot_id": "A0A8M1NBE9_DANRE", "id": "A0A8M1NBE9-1", "name": "Geranylgeranyl transferase type-2 subunit alpha", "aln": "MHGRVKVKTTAQQEEEKRKEREKKLKAFVCARDSVLKKRSAGEHDEEALDLTQQLLSSNPDFATLWNYRREVLLHLETLREKDEV--------------------------------QKLYESELHFIEACLKVNPKSYGCWHHRSWVNTRLPQPD---WTRELGLCDRCLSLDERNFHCWDYRRLVVK-----ESGVSVEQELQFTDRLIGSNFSNYSSWHYRSTLLPQLRPQPVLDSAHNTSPSPSASPQSHSHRVCEEQLLKEYELAHNAFFTDPNDQSAWFYYRWLLGRAEREEMISCVYVSREGERVSVAFSKPVHAGSVG--LMLVLDGQPQQVQWRNAHPRLRHSPVWLCDLPAGSISDTSNEHNLTIHWTDKHTHRDCALYTGCAESWCRDSATDQELFRSELSVEKSSVLQAELQSCNQLLDLEPQNKWCLLTIILLMRALDP--LGHEKETLTHFQTLKEVDAMRSSYYSDLCSKFLIENTILKMEYAEVR--VFSLSNKKLTTLCHLDQLLLVTHINLSSNQLQHLPPQFSMLQCLEVLEADDNAIESLEGLYHLPKLEEVSLKNNKICKVSDLETLATCTKLTRLDLRGNPVHKTDDLESELSLILPLVTALSL", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VN77-1", "uniprot_id": "Q9VN77_DROME", "id": "Q9VN77-1", "name": "Geranylgeranyl transferase type-2 subunit alpha", "aln": "MHGRVKVRTTEEERERKKKEQALKVRAYRAAMGRIQKKREAGELDNEMLSLTVQILLRNPDVSMLWNIRRECVLEKLFRLKEEEATCETPSEEKPEKENQTGENKPSEKKAAGEDKAHSIFTCELDLTEQCLMVNPKSYNAWHHRCWTLEQNPRAD---WQQEVKLCNKYLKFDERNFHTWDYRRYVTG-----KAMVPATQELDFCTEKIRANFSNYSSWHHRSLLLPELYPN-----------------QQRDRPMSEEKLQKELEMVLTAAFTDPNDSSAWFYQRWLLGSGAQLDRAPRIAAFRLESHGAVLALDKPYPDIKQLKTELVGGGQTILLEFWLP--VDKRGTSWKCQQNFDYQRNSAYSLRL------SDQKVDLSPLSGSENGAYYIAPPHG---TTSCSKDLLAELQTQLQSCLDLLEFEPDSKWTLLTSALLMRAIDF--SANHETSLAHLAKLEKVDFLREGYYKDLAARWTLEWELAKWPQSADFPKRFDIANAVLLESLPYDQYLVIADEITLPNKLR------------------DKLGESVPKTFADLKLQS-------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q00618-1", "uniprot_id": "PGTA_YEAST", "id": "Q00618-1", "name": "Geranylgeranyl transferase type-2 subunit alpha", "aln": "MHGIKRKQWTKELLRQKRVQDEKKIYDYRSLTENVLNMRDEKIYSIEALKKTSELLEKNPEFNAIWNYRRDIIASLASELE------------------------------------IPFWDKELVFVMMLLKDYPKVYWIWNHRLWVLKHYPTSSPKVWQTELAVVNKLLEQDARNYHGWHYRRIVVGNIESITNKSLDKEEFEYTTIKINNNISNYSAWHQRVQIISRMFQK-------------------GEVGNQKEYIRTEISYIINAMFTDAEDQSVWFYIKWFIKNDIVCKTLDEQEYLKMLK------------DLRENILLINND---------------------------------------------------------------------------------------------EIEFSGKQNIWCLKILLVLEDILEEKEALTERSSEQYLVQLIDADPLRKNRYLHLLEQHK-------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*** : : : : . *: : *: : . : : *. . . *. * ::* **:. :** **: : . : ** : * ** * *:** * : * .. * *: : : *. * **:* *.*** *. :*: : * *:****:** * ::..: : :: : * . .* ***.:*.*.*** :*:: . : . : . :: :. * * :* :: .. : :: * .* :* .* : ", "identical_positions": 66, "similar_positions": 81, "identity": "10.54%" }, { "cls_id": "homologset.agr.MGI:1860454", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D4A0M3-1", "uniprot_id": "D4A0M3_RAT", "id": "D4A0M3-1", "name": "", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MENELPVPHTSSRASITTNTSGTNSSSGCSSSSGGG---SGRPTAPQISVYSG-IPDRQTVQVIQQALHRQPS-TAAQYLQQMYAAQ----QQHLMLQTAALQQQHLSSAQLQSLAAVQQAS---------LVANRQGSTSGSSVSSQAPAQSSSLNLAASPAAAQLINRAQSVNSATASGLAQQAVLLGNTSSPALTASQAQMYLRAQM------------------------------------LIFTPTATVATVQPELGTGSPARPPTPAQVQNLTLRTQQTPAAAAAAAASGPAPTQPVLPSLALKPTPSSSQPLPPTPQGRTVVQGSPVG--AKPSVTDNVTEPLKT-DGNS----NMEARPGPDRATVPTVATHQLTAPAYTQLQP---HQLLPQPSSKHPQPQFVAQQQPQP----------PRPTPQVQSQPQLAAVSPSLALQPSPEGHAMPLGPV---------------------TQALPLQCSTAHVHKPGSSQQCHLPTPDSGSQNGHPEG--VSHAPQRRFQHTSAVILQLQPASPV----------------------------------------PQQCAPDDWKEVVPAEKSVPVTRPGLSPHQQAIITAIPGG---------------------------LPGPKSPNIQQCPAHETGQGIVHALTDLSSP-GMTSGNGNS---------ASSITGTAPQNGENKPP-------------------------------------------------------------------------------------QAIVKPQILTHVIEGFVIQEGAEPFPVGRSSLLVGNLKKKYAQGFLPEKLPQQDHTTTTDSEMEEPYLQESKEEGTPLKLKCELCGRVDFAYKFKRSKRFCSMACAKRYN-----VGCTKRVGLFHSDRSKLQKAGTTTHNRRRASKASLPTLTKDTKKQPSGTVPLSVTAALQLAH----SQEDSSRCSDNSSYEEPLSPISASSSTSRRRQGQRDLELSDMHMRDLVGMG-HHFLPSEPTKWNVEDVYEFIRSLPGCQEIAEEFRAQEIDGQALLLLKEDHLMSAMNIKLGPALKIYARISMLKDS------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9QWH1-1", "uniprot_id": "PHC2_MOUSE", "id": "Q9QWH1-1", "name": "Polyhomeotic-like protein 2", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MENELPVPHTSNRASVTTNTSGTNSSSGCISSSGGGGGSGGRPTAPQISVYSG-IPDRQTVQVIQQALHRQPS-TAAQYLQQMYAAQ----QQHLMLQTAALQQQHLSSAQLQSLAAVQQAS---------LVANRQGSTPGSSVSSQAPAQSSSLNLAASPAAAQLINRAQSVNSAAASGLAQQAVLLGNTSSPALTASQAQMYLRAQM------------------------------------LIFTPTATVATVQPELCTGSPARPPTPAQVQNLTLRTQQTP----AAAASGPPPTQPVLPSLALKPTPSSSQPLPAPPQGRTMAQGSPAG--AKPSGTDNAPETLKAGDGNC----NMEGRPGPGRA-VPAVATHPLIAPAYAHLQS---HQLLPQPPAKHPQPQFVAQQQPQP----------PRPAPQVQSQPQLASVSPSLALQSSPEDHALPLGSV---------------------TQALPLQCSTTHVHKPGNSQQCHLPTLDTGSQNGHPEG--GSHPPQRRFQHTSAVILQVQPASPVT---------------------------------------PQQCAPDDWKEVVPAEKSVPVARPGPSPHQQAIIPAIPGG---------------------------LPGPKSPNIQQCPAHETGQGIVHALTDLSSP-GMTSGNGNS---------ASSIAGTAPQNGENKPP-------------------------------------------------------------------------------------QAIVKPQILTHVIEGFVIQEGAEPFPVGRSSLLVGNLKKKYAQGFLPEKPPQQDHTTTTDSEMEEPYLQESKEEGTPLKLKCELCGRVDFAYKFKRSKRFCSMACAKRYN-----VGCTKRVGLFHSDRSKLQKAGTTTHNRRRASKASLPTLTKDTKKQPSGTVPLSVTAALQLAH----SQEDSSRCSDNSSYEEPLSPISASSSTSRRRQGQRDLDLPDMHMRDLVGVG-HHFLPSEPTKWNVEDVYEFIRSLPGCQEIAEEFRAQEIDGQALLLLKEDHLMSAMNIKLGPALKIYARISMLKDS------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8IXK0-1", "uniprot_id": "PHC2_HUMAN", "id": "Q8IXK0-1", "name": "Polyhomeotic-like protein 2", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MENELPVPHTSSSACATSSTSGASSSSGCNNSSSGG---SGRPTGPQISVYSG-IPDRQTVQVIQQALHRQPS-TAAQYLQQMYAAQ----QQHLMLQTAALQQQHLSSAQLQSLAAVQQAS---------LVSNRQGSTSGSNVSAQAPAQSSSINLAASPAAAQLLNRAQSVNSAAASGIAQQAVLLGNTSSPALTASQAQMYLRAQM------------------------------------LIFTPTATVATVQPELGTGSPARPPTPAQVQNLTLRTQQTP----AAAASGPTPTQPVLPSLALKPTPGGSQPLPTPAQSRNTAQASPAG--AKPGIADSVMEPHKKGDGNSSVPGSMEGRAGLSRT-VPAVAAHPLIAPAYAQLQP---HQLLPQPSSKHLQPQFVIQQQPQPQQQQPP-PQQSRPVLQAEPHPQLASVSPSVALQPSSEAHAMPLGPV---------------------TPALPLQCPTANLHKPGGSQQCHPPTPDTGPQNGHPEG--VPHTPQRRFQHTSAVILQLQPASPP-----------------------------------------QQCVPDDWKEVAPGEKSVPETRSGPSPHQQAIVTAMPGG---------------------------LPVPTSPNIQPSPAHETGQGIVHALTDLSSP-GMTSGNGNS---------ASSIAGTAPQNGENKPP-------------------------------------------------------------------------------------QAIVKPQILTHVIEGFVIQEGAEPFPVGRSSLLVGNLKKKYAQGFLPEKLPQQDHTTTTDSEMEEPYLQESKEEGAPLKLKCELCGRVDFAYKFKRSKRFCSMACAKRYN-----VGCTKRVGLFHSDRSKLQKAGAATHNRRRASKASLPPLTKDTKKQPTGTVPLSVTAALQLTH----SQEDSSRCSDNSSYEEPLSPISASSSTSRRRQGQRDLELPDMHMRDLVGMG-HHFLPSEPTKWNVEDVYEFIRSLPGCQEIAEEFRAQEIDGQALLLLKEDHLMSAMNIKLGPALKIYARISMLKDS------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8QHL5-1", "uniprot_id": "PHC2_DANRE", "id": "Q8QHL5-1", "name": "Polyhomeotic-like protein 2", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MEKEQEQGSVASSASVTIPSTTSVSTSTSAGTLSNS--SSRQQTVPQISVYGG-ITDRQTVQVIQQALNRQPSTVAAQYLQQMYAAQ----QQHLMLQTAALQQQHLS------LAAVQQAS---------IVAGRQSCSQHGSTSQQTVASQTTINLATSPAARHLISRAQSG-SSVPVCIGQQAVLLGNSSTPTLTASQAQMYLRAQMAQQTNLVQVA--------------RSLGRAVPLSSQLIFTPTASVTAIQPEAPAPSINTPPTSGQVQNLALRSQQGA--------LTSTLSQSQLQSLSVKQSVASVTGQSVARLKGLGAEPSPQGTAAKASPAETSSETTAKNDKTS----DLTTSVCPSVT---SVAGHPFISTAYTQIQT---HQLLQQH-----KQQFVIQQQPQI-------------LQRGQAQLLEAAAIHPHTVQAVAIQSALPAQPQ---------------------QCPIPLLPKVPVTCQQATIFHSTTVSQQALAQNGQAHI--LTHTKAPPLQLT-AVKCQIHPVQIQ-----------------------------------------QGVASQN----VP-DKDTPVL---LEPQLLSIPIQEPTR---------------------------TELRQSD--KESQVKENTQGSVNVKAGVGSPPAMTSGSGNN---------APTVTGSAPQNGESKPPP------------------------------------------------------------------------------------QAVVKPQILTHVIEGFVIQEGAEPFPVERPSLLIENLKQKQHHAYS----DLQKHN--ADSEMEDLSLQELNNQPEPVR-TCEFCGNVDFAFNFKRSKRFCSTVCAKRYN-----VGCTKRMGLFPG------KSSPEDTKKPKASDESPKNCSTETRKR-NPSIQTTTGASLLSPHPSHPSHGESSQCSDMSSYEEPISPLSNSSFG-----APIEHEESFDHSRELTPLLTQHFLASDPTKWNVEDVYEFICSLPGCHEIAEEFRSQEIDGQALMLLKEDHLMSTMNIKLGPALKIFARISMLKDS------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9W523-1", "uniprot_id": "Q9W523_DROME", "id": "Q9W523-1", "name": "", "aln": "MPHGFGAAPSVSVSGDTESESATTIRTPPPS--------PEATTSVKVNSTTRVDP--------------------------------QRPLRCLETLAQKAGISFDEDFAKSPSQSP---SSKAARGS---------------VGTPSIRRRHPLLPLSSRSPSAPDS---------KTTGRKLEKSQSPAQQVAAATNVPLQISPEQLQQLYANNPYAIQVKQEFPTHTTSGSGTELKHATNIMEVQQQLQLQQQLSEANGGGAASAGAGGAASPANSQQSQQQQHSTAISTMSPMQLAAATGGVGGDWTQGRTVQLMQPSTSFLYPQMIVSGNLLHPGGLGQQPIQVITAGKPFQGNGPQMLTTTTQNAKQMIGGQAGFAGGNYATCIPSNHNQSPQTVLISPVNVISHSPQQQQNLLQSMAAAAQQQQLTQQQQQQLNQQQQQLNQQQQQQQLTAALAKVGVDAQGKLAQKVVQKVTTTSSTVQAATGPGSTGSTQTQQVQQVQQQQQQTTQTTQQCVQVSQSTLPVGVGGQSVQTAQLLNAGQAQQMQIPWFWQNAAGLQPFGSNQIILRNQPDGTQGMFIQQQPATQTLQTQQNQIIQCNVTQTPTKARTQLDALAPKQQQQQQQVGTTNQTQQQQLAVATAQLQQQQQQLTAAALQRPGAPVMPHNGTQVRPASSVSTQTAQNQSLLKAKMRNKQQPVRPALATLKTEIGQVAGQNKVVGHLTTVQQQQQATNLQQVVNAAGNKMVVMSTTGTPITLQNGQTLHAATAAGVDKQQQQLQLFQKQHILQQQ-MLQQQIAAIQMQQQQAAVQAQQQQQQQVSQQQQVNAQQQQAVAQ--QQQAVAQAQQQQREQQQQVAQAQAQHQQALANATQQILQVAPNQFITSHQQQQQQQLHNQLIQQQLQQQAQAQVQAQVQAQAQQQQQQREQQQNIIQQIVVQQSTGATSQQQQQQPQQQSGQLQLSSVPFSVSPSMTAEDIAGITSSALQEALSVSGAIFQTTKPITCSSSTLPTSSVVTITSQSSTPLVTSSTVASMQQAQTQGTQIHQHQQLISATIAGGSQQQQQQQQLGLPSLTPTTPSPTTNPILAMTSMMNATVGHLSTAPP--VSVSSTAVTPSSGQLVTLSSASSGGGAGFPATPTKETPSKGPTATLVPIDSPKTPVSGKDTCTTPKSSTPATVSASVEASSSTGEALSNGDASDRSSTPSKGATTPTSKQSNAAVQPPSSTIPNSVSGKEEPKLTTCGSLTSATSTSTTTTITNGIGVARTTASTAVSTASTTTTSSGTFTTSCTSTTTTTTSSISNGSKDLPKAMIKPNVLTHVIDGFIIQEANEPFPVTRQRYADKDVS--------------DEPPKKKATMQEDIKLSGIASAPGSDMVACEQCGKMEHKAKLKR-KRYCSPGCSRQAKNGIGGVGSGETNGLGTGGIVGVDAMALVDRLDEAMAEEKMQTESYQTVSDALPIQAATPEVPPISMP---VLAAMSTSSPLSLPLTLPLPIAIAPTVSLPVVSAGVVAPVLAIPSSNINGSD-----RPPISSWSVEEVSNFIRELPGCQDYVDDFIQQEIDGQALLLLKENHLVNAMGMKLGPALKIVAKVESIKEVPP-GDVKD----", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P39769-1", "uniprot_id": "PHP_DROME", "id": "P39769-1", "name": "Polyhomeotic-proximal chromatin protein", "aln": "MDR--RALKFMQKRADTESDTTTPVSTTASQGISASAILAGGTLPLKDNSNIREKPLHHNYNHNNNNSSQHSHSHQQQQQQQVGGKQLERPLKCLETLAQKAGITFDEKYDVASPPHPGIAQQQATSGTGPATGSGSVTPTSHRHGTPPTGRRQTHTPSTPNRPSAPSTPNTNCNSIARHTSLTLEKAQNPGQQVAATTTVPLQISPEQLQQFYASNPYAIQVKQEFPTHTTSGSGTELKHATNIMEVQQQLQLQQQLSEANGGGAASAGAGGAASPANSQQSQQQQHSTAISTMSPMQLAAATGGVGGDWTQGRTVQLMQPSTSFLYPQMIVSGNLLHPGGLGQQPIQVITAGKPFQGNGPQMLTTTTQNAKQMIGGQAGFAGGNYATCIPTNHNQSPQTVLFSPMNVIS--PQQQQNLLQSMAAAAQQQQLTQQQQQFNQQQQQQLTQQQQQ--LTAALAKVGVDAQGKLAQKVVQKVTTTSSAVQAATGPGSTGSTQTQQVQQVQQQQQQTTQTTQQCVQVSQSTLPVGVGGQSVQTAQLLNAGQAQQMQIPWFLQNAAGLQPFGPNQIILRNQPDGTQGMFIQQQPATQTLQTQQNQIIQCNVTQTPTKARTQLDALAPKQQQQQQQVGTTNQTQQQQLAVATAQLQQQQQQLTAAALQRPGAPVMPHNGTQVRPASSVSTQTAQNQSLLKAKMRNKQQPVRPALATLKTEIGQVAGQNKVVGHLTTVQQQQQATNLQQVVNAAGNKMVVMSTTGTPITLQNGQTLHAATAAGVDKQQQQLQLFQKQQILQQQQMLQQQIAAIQMQQQQAAVQAQQQQQQQVSQQQQVNAQQQQAVAQ--QQQAVAQAQQQQREQQQQVAQAQAQHQQALANATQQILQVAPNQFITSHQQQQQQQLHNQLIQQQLQQQAQAQVQAQVQAQAQQQQQQREQQQNIIQQIVVQQSGATSQQTSQQQQHHQSGQLQLSSVPFSVSSSTTPAGIA--TSSALQAALSASGAIFQTAKPGTCSSSS-PTSSVVTITNQSSTPLVTSSTVASIQQAQTQSAQVHQHQQLISATIAGGTQQQPQ----GPPSLTPTT-----NPILAMTSMMNATVGHLSTAPPVTVSVTSTAVTSSPGQLVLLSTASSGGGGSIPATPTKETPSKGPTATLVPIGSPKTPVSGKDTCTTPKSSTPATVSASVEASSSTGEALSNGDASDRSSTPSKGATTPTSKQSNAAVQPPSSTTPNSVSGKEEPKLATCGSLTSATSTSTTTTITNGIGVARTTASTAVSTASTTTTSSGTFITSCTSTTTTTTSSISNGSKDLPKAMIKPNVLTHVIDGFIIQEANEPFPVTRQRYADKDVS--------------DEPPKKKATMQEDIKLSGIASAPGSDMVACEQCGKMEHKAKLKR-KRYCSPGCSRQAKNGIGGVGSGETNGLGTGGIVGVDAMALVDRLDEAMAEEKMQTEATPKLSESFPILGASTEVPPMSLP---VQAAISAPSPLAMPLGSPLSVALPTLAPLSVVTSGAAP-----KSSEVNGTD-----RPPISSWSVDDVSNFIRELPGCQDYVDDFIQQEIDGQALLLLKEKHLVNAMGMKLGPALKIVAKVESIKEVPPPGEAKDPGAQ", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :::: :. . : . . : **. : .. *.. * *..**. . . ::** *:* **: ::* . * : **. ** . : . : . * :::: . :*. : .:.:. * . :*::* .: . .. * *:::: ::::.*.: ::* : . . * *:* * :* . * . ::: . : : : . :: : : . . ** : : :. : * :**: * : *. * *.* : : .: * : . .:. : . : . . ..:. . . :* : : *:: . . . * ... .. . * :.. . * . . .*. . : ..*: ..: . : .*. :** :*::**::*****:**:***. ***** * ::. :. : *: *. . . ** **.::. ::** **:** *::: : **. : ** . . :. . : . . : .. *: .. . *:. . . :: . :.*.*::* :** .****:: .::* ********:****.**:.:*.:******** *::. :*: ", "identical_positions": 128, "similar_positions": 234, "identity": "7.82%" }, { "cls_id": "homologset.agr.MGI:1860456", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "F1LQJ7-1", "uniprot_id": "F1LQJ7_RAT", "id": "F1LQJ7-1", "name": "Phosphoenolpyruvate carboxykinase [GTP], mitochondrial", "aln": "TLLPSPPSLTPRLHWFLWPSRSASPGAMAAMYLPGLRLS--------WHRLRPWCRSPCRSIQTLRVLSGDLSQLPAGVRDFVERSAHLCQPAGIHICDGTEAENAATLALLEEQGLIRKLPKYENCWLARTDPKDVARVESKTVIVTSSQRDTVPLLAGGASGQLGNWMSPDEFQRAVDQRFPGCMQGRTMYVLPFSMGPLGSPLSRIGVQLTDSPYVVASMRIMTRLGTHVLQALGD-GDFIKCLHSVGQPLTGHGDPVGRWPCNPEKTLIGHVPEQREIVSFGSGYGGNSLLGKKCFALRIASRLARDEGWLAEHMLILGITNPAGKKRYVAAAFPSACGKTNLAMMRPALPGWKVECVGDDIAWMRFDSEGQLRAINPENGFFGVAPGTSATTNPNAMATIQSNTVFTNVAETSDGGVYWEGIDQPLPPGVTVTSWLGKPWKPGDKEPCAHPNSRFCVPARQCPIMDPAWEAPEGVPIDAIIFGGRRPKGVPLVYEAFSWRHGVFVGSAMRSESTAAAEHKGKTIMHDPFAMRPFFGYNFGHYLEHWLSMEGRKGARLPRIFHVNWFRRDEAGRFLWPGFGENARVLDWICRRLGGEDSARETPIGLVPKEGALDLSGLR-AIDTSQLFSIPKDFWEQEVRDIRSYLTEQVNQDLPKEVLAELEALEERVQKM", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8BH04-1", "uniprot_id": "PCKGM_MOUSE", "id": "Q8BH04-1", "name": "Phosphoenolpyruvate carboxykinase [GTP], mitochondrial", "aln": "---------------------------MAAMYLPGLRLS--------RHGLRPWCWSPCRSIQTLHVLSGDMSQLPAGVRDFVARSAHLCQPEGIHICDGTEAENTAILALLEEQGLIRKLPKYKNCWLARTDPKDVARVESKTVIVTPSQRDTVPLLAGGARGQLGNWMSPDEFQRAVDERFPGCMQGRIMYVLPFSMGPVGSPLSRIGVQLTDSAYVVASMRIMTRLGTPVLQALGD-GDFIKCLHSVGQPLTGHGDPVGQWPCNPEKTLIGHVPDQREIVSFGSGYGGNSLLGKKCFALRIASRLARDEGWLAEHMLILGITNPAGKKRYVAAAFPSACGKTNLAMMRPALPGWKVECVGDDIAWMRFDSEGQLRAINPENGFFGVAPGTSAATNPNAMATIQSNTLFTNVAETSDGGVYWEGIDQPLPPGVTITSWLGKPWKPGDKEPCAHPNSRFCVPARQCPIMDPAWEAPEGVPIDAIIFGGRRPKGVPLVYEAFNWRHGVFVGSAMRSESTAAAEHKGKTIMHDPFAMRPFFGYNFGRYLEHWLSMEGQKGARLPRIFHVNWFRRDEAGRFLWPGFGENARVLDWICRRLEGEDSAQETPIGLVPKEGALDLSGLS-AVDTSQLFSIPKDFWEQEVRDIRGYLTEQVNQDLPKEVLAELEALEGRVQKM", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q16822-1", "uniprot_id": "PCKGM_HUMAN", "id": "Q16822-1", "name": "Phosphoenolpyruvate carboxykinase [GTP], mitochondrial", "aln": "---------------------------MAALYRPGLRLN--------WHGLSPLGWPSCRSIQTLRVLSGDLGQLPTGIRDFVEHSARLCQPEGIHICDGTEAENTATLTLLEQQGLIRKLPKYNNCWLARTDPKDVARVESKTVIVTPSQRDTVPLPPGGARGQLGNWMSPADFQRAVDERFPGCMQGRTMYVLPFSMGPVGSPLSRIGVQLTDSAYVVASMRIMTRLGTPVLQALGD-GDFVKCLHSVGQPLTGQGEPVSQWPCNPEKTLIGHVPDQREIISFGSGYGGNSLLGKKCFALRIASRLARDEGWLAEHMLILGITSPAGKKRYVAAAFPSACGKTNLAMMRPALPGWKVECVGDDIAWMRFDSEGRLRAINPENGFFGVAPGTSATTNPNAMATIQSNTIFTNVAETSDGGVYWEGIDQPLPPGVTVTSWLGKPWKPGDKEPCAHPNSRFCAPARQCPIMDPAWEAPEGVPIDAIIFGGRRPKGVPLVYEAFNWRHGVFVGSAMRSESTAAAEHKGKIIMHDPFAMRPFFGYNFGHYLEHWLSMEGRKGAQLPRIFHVNWFRRDEAGHFLWPGFGENARVLDWICRRLEGEDSARETPIGLVPKEGALDLSGLR-AIDTTQLFSLPKDFWEQEVRDIRSYLTEQVNQDLPKEVLAELEALERRVHKM", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P20007-1", "uniprot_id": "PCKG_DROME", "id": "P20007-1", "name": "Phosphoenolpyruvate carboxykinase [GTP]", "aln": "---------------------------MPELIEQSKIISGNVCGLPQLHKLRQDNCGLYSHIRGIPISYGNVDLLTTGVRAFVEEGIALCQPDQVHICDGSEQENKVLIKSLLEAGTIVPLPKYDNCWLARTNPADVARVESRTFICTERREETIPTPVEGVKGTLGNWISPSDMDAAVQQRFPGCMKGRTMYVVPFSMGPVGSPLSKIGIELTDSAYVVASMRIMTRMGAAVLRQLAKKEEFVRALHSVGAPANGQVEQP-SWPCDPERTIILHKPAENLIVSYGSGYGGNSLLGKKCFALRIGSTIAKQEGWLAEHMLILGITDPKGEKKYITAAFPSACGKTNLAMLNPSLANYKVECVGDDIAWMKFDSQGVLRAINPENGFFGVAPGTSMETNPIAMNTVFKNTIFTNVASTSDGGVFWEGMESSLAPNVQITDWLGKPWTKDSGKPAAHPNSRFCTPAAQCPIIDEAWEDPAGVPISAMLFGGRRPAGVPLIYEARDWTHGVFIGAAMRSEATAAAEHKGKVIMHDPFAMRPFFGYNFGDYVAHWLSME--KRGQVPKIFHVNWFRKSAEGKFMWPGYGENSRVLEWILRRVNGESCYVDSAIGHIPAEGALNLDGMKDKVDVKEIFSLPKEFWSQEVKDIRTYFESQVGADLPASIYQQLDELSSRVDNL", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *. : . :. * * *: : : *::. *.:*:* ** .. **** :*****:* ** . : * : * * ****.*******:* *******:*.* * :.:*:* *. * ****:** ::: **::******:** ***:******:*****:**::****.***********:*: **: *.. :*::.***** * .*: : ***:**:*:* * * :. *:*:*******************.* :*::**************.* *:*:*::**************:.*:*..:************:***:* ****************** *** ** *: .**:*****.******:***::..*.*.* :*.******. .. :*.********.** ****:* *** * ****.*::****** ****:*** .* ****:*:*****:********* ***************** *: ****** * .::*:********:. *:*:***:***:***:** **: **.. ::.** :* ****:*.*: :*..::**:**:**.***:*** *: .**. *** .: :*: *. **.::", "identical_positions": 383, "similar_positions": 149, "identity": "56.57%" }, { "cls_id": "homologset.agr.MGI:1860476", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P12760-1", "uniprot_id": "NMU_RAT", "id": "P12760-1", "name": "Neuromedin-U", "aln": "MSRAANRRPGLSAGQLAAATASPLLSLLLLLACCADACRGTPISPQRLPPEQELQLWNEIPEACASFLSVDSQPQASVALRKLCRVLMEIFQKPQEQTEKDNAKRFLFHYSKTQKLGNSNVVSSVVHPLLQLVPQLHERRMKRYKVN-EYQGP-VAPSGGFFLFRPRNGKRSTSFI", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9QXK8-1", "uniprot_id": "NMU_MOUSE", "id": "Q9QXK8-1", "name": "Neuromedin-U", "aln": "MSRAAGHRPGLSAGQLAAATASPLLSLLLLLACCADACKGVPISPQRLQPEQELQLWNEIHEACASFLSIDSRPQASVALRELCRIVMEISQKPQEQSEKDNTKRFLFHYSKTQKLGNSNVVSSVVHPLLQLVPQLHERRMKRFKA--EYQSPSVGQSKGYFLFRPRNGKRSTSFI", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P48645-1", "uniprot_id": "NMU_HUMAN", "id": "P48645-1", "name": "Neuromedin-U", "aln": "MLRTESCRPRSPAGQVAAA--SPLLLLLLLLAWCAGACRGAPILPQGLQPEQQLQLWNEIDDTCSSFLSIDSQPQASNALEELCFMIMGMLPKPQEQDEKDNTKRFLFHYSKTQKLGKSNVVSSVVHPLLQLVPHLHERRMKRFRVDEEFQSPFASQSRGYFLFRPRNGRRSAGFI", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F1R3S7-1", "uniprot_id": "F1R3S7_DANRE", "id": "F1R3S7-1", "name": "", "aln": "MRNSNQCERATAHSAMSPGNTSALMLAVLLLSFIP-ITTSAPMLLNPSSLEHE-QLLTQITDLCSFYLSADPSFRTSDVLEDLCFLMLGSLQKSKEITARETSKRFLFHYTKPNGAGLSDGTSTVLHPLLELIPQLARRRSRRMKLNENLQGPGRIQSRGYFLYRPRNGRRSDEYV", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* .: . . . ::.. *.*: :***: . ..*: : *:: ** .:* : *: :** *. ::* .*..** ::: *.:* ::.:*******:*.: * *: .*:*:****:*:*:* .** :* : : *.* * *:**:*****:** ::", "identical_positions": 56, "similar_positions": 60, "identity": "31.82%" }, { "cls_id": "homologset.agr.MGI:1860483", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZVR2-1", "uniprot_id": "D3ZVR2_RAT", "id": "D3ZVR2-1", "name": "Mesogenin-1", "aln": "MDNLGETFLSLEDGLDSSDTTGLLASWDWKSRARPLELIQASPTQSLSPVPSLESYS-----EVA-LPCGHSGASTGGSDGYSSHEAGGLVELDYSMLAFQPSYIHAAGGLKGQKGSKVKMSVQRRRKASEREKLRMRTLADALHTLRNYLPPVYSQRAQATERVSCAPWRTPPVPDLWIGRGGVLKPPEPVVSQDNSTELSVDT", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9JK54-1", "uniprot_id": "MSGN1_MOUSE", "id": "Q9JK54-1", "name": "Mesogenin-1", "aln": "MDNLGETFLSLEDGLDSSDTAGLLASWDWKSRARPLELVQESPTQSLSPAPSLESYS-----EVA-LPCGHSGASTGGSDGYGSHEAAGLVELDYSMLAFQPPYLHTAGGLKGQKGSKVKMSVQRRRKASEREKLRMRTLADALHTLRNYLPPVYSQRGQPLTKIQTLKYTIK-----YIGELTDLLNS----SGREPRPQSV--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A6NI15-1", "uniprot_id": "MSGN1_HUMAN", "id": "A6NI15-1", "name": "Mesogenin-1", "aln": "MDNLRETFLSLEDGLGSSDSPGLLSSWDWKDRAGPFELNQASPSQSLSPAPSLESYSSSPCPAVAGLPCEHGGASSGGSEGCSVGGASGLVEVDYNMLAFQPTHLQGGGGPKAQKGTKVRMSVQRRRKASEREKLRMRTLADALHTLRNYLPPVYSQRGQPLTKIQTLKYTIK-----YIGELTDLLNR-----GREPRAQSA--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q90ZL1-1", "uniprot_id": "MSGN1_DANRE", "id": "Q90ZL1-1", "name": "Mesogenin-1", "aln": "MAQIDVDVF----------TAKVLSHWDWSREDRSFGDSASSPES--------ESFD--------------SACSS--PDARSSPTAG---------------CEHAE-----QQKPKVKMSMRRRMKASEREKLRMRSLAEALHQLRDYLPPGYSRRGQPLTKIQTLKYTIQ-----YIKELSGILEQQ---------------", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* :: .: :. :*: ***. . .: ** . **:. ...*: .:. . *. : *: .**:**::** ***********:**:*** **:**** **:*.*. ::. : :* . : ", "identical_positions": 45, "similar_positions": 43, "identity": "21.95%" }, { "cls_id": "homologset.agr.MGI:1860484", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O08976-1", "uniprot_id": "PBAS_MOUSE", "id": "O08976-1", "name": "Probasin", "aln": "MMRVIILLLTLHVLGVSSVMS---LKKKIDGPWQTIYLAASTMEKINEGSPLRTYFRHILCGRRCNQVYLYFFIKKGTKCQLYKVIGRKKQEVYYAQYEGSIAFMLKMVNEKILLFHYFNKNRRNDVTRVAGVLAKGKQLNKEEMTEFMNLVEEMGIEEENVQRIMDTDNCPSKIKP-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P15399-1", "uniprot_id": "PBAS_RAT", "id": "P15399-1", "name": "Probasin", "aln": "-MRVILLLLTLDVLGVSSMMTDKNLKKKIEGNWRTVYLAASSVEKINEGSPLRTYFRRIECGKRCNRINLYFYIKKGAKCQQFKIVGRRSQDVYYAKYEGSTAFMLKTVNEKILLFDYFNRNRRNDVTRVAGVLAKGRQLTKDEMTEYMNFVEEMGIEDENVQRVMDTDTCPNKIRIR", "tax_id": 10116, "tax_name": "Rat" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ****:*****.******:*: *****:* *:*:*****::**************:* **:***:: ***:****:*** :*::**:.*:****:**** ***** ********.***:****************:**.*:****:**:*******:*****:****.**.**: ", "identical_positions": 132, "similar_positions": 34, "identity": "74.16%" }, { "cls_id": "homologset.agr.MGI:1860485", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9JHK5-1", "uniprot_id": "PLEK_MOUSE", "id": "Q9JHK5-1", "name": "Pleckstrin", "aln": "MEPKRIREGYLVKKGSVFNTWKPMWVVLLEDGIEFYKKKSDNSPKGMIPLKGSTLTSPCQDFGKRMFVLKITTTKQQDHFFQAAFLEERDAWVRDIKKAIKCIEGGQKFARKSTRRSIRLPETIDLGALYLSMKDPEKGIKELNLEKDKKVFNHCLTGSGVIDWLVSNKLVRNRQEGLMISASLLSEGYLQPAGDLSKNAADGIAENPFLDSPDAFYYFPDSGFFCEENSSDDDVILREEFRGVIIKQGCLLKQGHRRKNWKVRKFILREDPAYLHYYDPAGGEDPLGAVHLRGCVVTSVESSHDVKKSDEENLFEIITADEVHYYLQAATSKERTEWIKAIQVASRTGK", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q4KM33-1", "uniprot_id": "PLEK_RAT", "id": "Q4KM33-1", "name": "Pleckstrin", "aln": "MEPKRIREGYLVKKGSVFNTWKPMWVVLLEDGIEFYKKKSDNNPKGMIPLKGSTLTSPCQDFGKRMFVLKITTTKQQDHFFQAAYLEERDAWVRDIKKAIKCIEGGQKFARKSTRRSIRLPETIDLGALYLSMKDPEKGIKELNLEKDKKVFNHCFTGSGVIDWLVSNKLVRNRQEGLMISASLLSEGYLQPASDLSKNAADGIAENPFLDNPDAFYYFPDSGFFCEENSSDDDIILKEEFRGIIIKQGCLLKQGHRRKNWKVRKFILREDPAYLHYYDPAGGEDPLGAIHLRGCVVTSVESNPDGKKSDEENLFEIITADEVHYYMQAATAKERTEWIKAIQVASRTGK", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P08567-1", "uniprot_id": "PLEK_HUMAN", "id": "P08567-1", "name": "Pleckstrin", "aln": "MEPKRIREGYLVKKGSVFNTWKPMWVVLLEDGIEFYKKKSDNSPKGMIPLKGSTLTSPCQDFGKRMFVFKITTTKQQDHFFQAAFLEERDAWVRDIKKAIKCIEGGQKFARKSTRRSIRLPETIDLGALYLSMKDTEKGIKELNLEKDKKIFNHCFTGNCVIDWLVSNQSVRNRQEGLMIASSLLNEGYLQPAGDMSKSAVDGTAENPFLDNPDAFYYFPDSGFFCEENSSDDDVILKEEFRGVIIKQGCLLKQGHRRKNWKVRKFILREDPAYLHYYDPAGAEDPLGAIHLRGCVVTSVESNSNGRKSEEENLFEIITADEVHYFLQAATPKERTEWIRAIQMASRTGK", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "******************************************.*************************:***************:**************************************************.**************:****:**. ********: **********::***.*******.*:**.*.** *******.**********************:**:*****:**************************************.******:************. : :**:***************::****.*******:***:******", "identical_positions": 315, "similar_positions": 30, "identity": "90.0%" }, { "cls_id": "homologset.agr.MGI:1860486", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q3T1H5-1", "uniprot_id": "TYDP2_RAT", "id": "Q3T1H5-1", "name": "Tyrosyl-DNA phosphodiesterase 2", "aln": "MASGSSSDAAESAEPA----AAPAAAETEEDQVKRRRLQSLGFALVTSCDTTVASTFLSENNWQTKKALSAFFEQPEN---DLARPHQPPTSSKSED------------------YVDLTNEDANDTTIL---ETSPS-GTPLEDS--STISFITWNIDGLDGCNLPERARGVCSCLALYSPDVVFLQEVIPSYCAYLRKRARTYNIITGNEEGYFTAILLKKGRVKFKGQEIIPFPNTKMMRNLLCVNVSLGGNEFCLMTSHLESTRKHSAERINQLKTVFQKMQEATDSTTVIFAGDTNLRDQEVIKCGGLPDNVFDAWEFLGKPKHCRYTWDTKANDNLRIPAACKHRFDRIFFR--AEEGHLIPQSLDLIGLERLDCGRFPSDHWGLLCTLNVVL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9JJX7-1", "uniprot_id": "TYDP2_MOUSE", "id": "Q9JJX7-1", "name": "Tyrosyl-DNA phosphodiesterase 2", "aln": "MASGSSSDAAEPAGPAGRAASAPEAAQAEEDRVKRRRLQCLGFALVGGCDPTMVPSVLRENDWQTQKALSAYFELPEN---DQGWPRQPPTSFKSEA------------------YVDLTNEDANDTTIL---EASPS-GTPLEDS--STISFITWNIDGLDGCNLPERARGVCSCLALYSPDVVFLQEVIPPYCAYLKKRAASYTIITGNEEGYFTAILLKKGRVKFKSQEIIPFPNTKMMRNLLCVNVSLGGNEFCLMTSHLESTREHSAERIRQLKTVLGKMQEAPDSTTVIFAGDTNLRDQEVIKCGGLPDNVFDAWEFLGKPKHCQYTWDTKANNNLRIPAAYKHRFDRIFFR--AEEGHLIPQSLDLVGLEKLDCGRFPSDHWGLLCTLNVVL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O95551-1", "uniprot_id": "TYDP2_HUMAN", "id": "O95551-1", "name": "Tyrosyl-DNA phosphodiesterase 2", "aln": "MELGSCLEGGR-----------EAAEEEGEPEVKKRRLLCVEFASVASCDAAVAQCFLAENDWEMERALNSYFEPPVE---ESALERRPETISEPKT------------------YVDLTNEETTDSTTS---KISPSEDTQQENG--SMFSLITWNIDGLDLNNLSERARGVCSYLALYSPDVIFLQEVIPPYYSYLKKRSSNYEIITGHEEGYFTAIMLKKSRVKLKSQEIIPFPSTKMMRNLLCVHVNVSGNELCLMTSHLESTRGHAAERMNQLKMVLKKMQEAPESATVIFAGDTNLRDREVTRCGGLPNNIVDVWEFLGKPKHCQYTWDTQMNSNLGITAACKLRFDRIFFRAAAEEGHIIPRSLDLLGLEKLDCGRFPSDHWGLLCNLDIIL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q5XJA0-1", "uniprot_id": "TYDP2_DANRE", "id": "Q5XJA0-1", "name": "Tyrosyl-DNA phosphodiesterase 2", "aln": "------------------------MSALGESRTR----LCDQFAFVSGSDSAVAQCYLAENEWDMERALNSFFEAHMDSVFDEEAEKTEVTGNKRKDDTAEASGTKKKLKTDNADCIDLTAEEPTCSITVNSKENQAENGTAKSEVEDSKLSIISWNVDGLDTLNLADRARGLCSYLALYTPDVVFLQELIPAYVQYLKKRAVSYLFFEGSDDGYFTGIMLRKSRVKFLESEIICFPTTQMMRNLLIAQVTFSGQKLYLMTSHLESCKNQSQERTKQLRVVLQKIKEAPEDAIVIFAGDTNLRDAEVANVGGLPAGVCDVWEQLGKQEHCRYTWDTKANSNKTVPYVSRCRFDRIFLRSAKTAPPVTPDHMALIGMEKLDCGRYTSDHWGIYCTFNT--", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * ..: . ** * ..*.::. * **:*: ::**.::** : : : * : : :*** *:.. : : ... .* .: * :*:*:**:**** **.:****:** ****:***:****:**.* **:**: .* :: * ::****.*:*:*.***: .*** **.*:****** .:*...*::: ******** : :: ** .**: *: *::**.:.: *********** ** . **** .: *.** *** :**:*****: *.* :. . : ******:* : * : *:*:*:*****:.*****: *.:: ", "identical_positions": 150, "similar_positions": 104, "identity": "37.59%" }, { "cls_id": "homologset.agr.MGI:1860488", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9CQW3-1", "uniprot_id": "PROZ_MOUSE", "id": "Q9CQW3-1", "name": "Vitamin K-dependent protein Z", "aln": "MAGCILLLRGFIL----TLILHQVELSVFLPAPKANNVLRRWRRGSSYFLEEIFQGNLEKECYEEVCNYEEAREVFENDVITDEFWRQYGGGSPCVSQPCLNNGTCEDHIRSYSCTCSPGYEGKTCAMAKNECHLERTDGCQHFCHPGQSSYMCSCAKGYKLGKDQKSCGPSDKCACGALTSEHIRMTKSS-----------QSQPSFPWQVRLTNSEGEDFCAGVLLQEDFVLTTAKCSLLHSNISVKANVDQR--------IRIKSTHVHMRYDEESGENDVSLLQLEEPLQCPSSGLPVCVPERDFAEHVLIP-GTEGLLSGWMLN--GTHLATTPMLLSVTQADGEECGQTLNVTVTTR--TSCEKG---SVVMGPWVEGSVVTREHKGTWFLTGILGSPPPPGQSQMLLLTAVPRYSMWFKQIMK-------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "G3V8K8-1", "uniprot_id": "G3V8K8_RAT", "id": "G3V8K8-1", "name": "Vitamin K-dependent protein Z", "aln": "MADCISLHRGFILSFVLTLALHQVELSVFLPASEANNILLRWRRASSYLLEEFLQGNLERECYEEICNLEEAREVFENDASTDEFWSQYSGGFPCISQPCLNNGTCKDHIRSFSCTCAPGYEGKTCAMAKNECHLERTDGCQHFCHPGQSSYMCSCAKGYKLGEDHRSCSPSDKCACGALTSQHIRTQMTDD--------ICRSWPSFPWQVRLTNSEGEDFCAGVLLQENFVLTTAKCSLLHSNLSVKADDDQQ--------IRIKSAHVHMRYDKETGENDVSLLELEKPLQCPIPALPVCVPERDFAEHVLIP-GTKGVLSGWMLN--GIDLDRTLTMLSVTQTDGEECGQILNVTVTTR--TSCEKG---SEVMGPWVEGSVVTRQHKGTWFLTGILSSPPPPGQSHMLLLTSVPRYSMWFNQIMK-------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P22891-1", "uniprot_id": "PROZ_HUMAN", "id": "P22891-1", "name": "Vitamin K-dependent protein Z", "aln": "MAGCVPLLQGLVL----VLALHRVEPSVFLPASKANDVLVRWKRAGSYLLEELFEGNLEKECYEEICVYEEAREVFENEVVTDEFWRRYKGGSPCISQPCLHNGSCQDSIWGYTCTCSPGYEGSNCELAKNECHPERTDGCQHFCLPGQESYTCSCAQGYRLGEDHKQCVPHDQCACGVLTSEKRAPDLQD----------------LPWQVKLTNSEGKDFCGGVIIRENFVLTTAKCSLLHRNITVKTYFNRTSQDP--LMIKITHVHVHMRYDADAGENDLSLLELEWPIQCPGAGLPVCTPEKDFAEHLLIP-RTRGLLSGWARN--GTDLGNSLTTRPVTLVEGEECGQVLNVTVTTR--TYCERS---SVAAMHWMDGSVVTREHRGSWFLTGVLGSQPVGGQAHMVLVTKVSRYSLWFKQIMN-------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F1Q5S2-1", "uniprot_id": "F1Q5S2_DANRE", "id": "F1Q5S2-1", "name": "", "aln": "MACLGIYLSLAVLFGFVTAGLHKRSAPVFLEKWDALNVISRQKRSNTGDEETKLPANLERECLEEVCDYEEAREVFQDNYRTDIFWSVYIDGDQCADQPCKNGAMCSDSVGGYDCICKSGFTGTHCETDQTVCLIDKSKGCSQFCKPGYHSYECSCAYGWKLQQKEK-CVPAVTFPCGKVGSVSQWERRQSENIKSEYEGFPCGPEECPWQAMLLRGSS-GFCSGVILKENLVLTTAQCARKHPDFQVAVGKRMTMFESSGQTLAVRQVHLHPLHSTGTAENDLALLELRDRIIFKKSVAAACLPERDFADRVLTAGQYMGVVTGWKDTPTEDGIEGHLLLNHLSYQTLQDCSRQHSAQVSSNKLMCSLPR---AKADCVFGQGSPVLTLHREVFFLTGMVSRPAGADCRSGYILQKVSRALPWLNSIMSP------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "F1QZU6-1", "uniprot_id": "F1QZU6_DANRE", "id": "F1QZU6-1", "name": "", "aln": "MESLVYRLLFFMLIT--HHVSSGDQRTVFRSRRRANALLLRSRRANTFLLEEILQGNLERECYEEKCSKEEARECFENDQKTNEFWAKYYDGDQCRSNPCQHGGTCKDGIGRYTCTCAEAYSGHDCQTDKSQCPSAGPLACEHFCRPSTAAYRCFCARGYTLNSDGRSCSPNVQNPCGTTEMSSFCPDGRCS-----------------WEVRFLNASGHDVCHGVILGQKSILTSATCMTALQDLHFTVAVGVS-----TAAVRVSSWTPHKRFLSGP-DDDLCFLELQEPFPPNISTVPLCLPEKDYSENILMRAGREGVAEGGATY---------------SYLSLDDCRDALNLTFVMTNKMFCMKRESAGSERCTVSSGSPAATLEGKTAFLTGVSLSAGRCG--DTLLFTKLSRYLHWLRPLLLASEREQP", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* :* . .** * :: * :*..: * : .***:** ** * ***** *::: *: ** * .* * .:** :.. *.* : : * * .: * * :. * . .*.:** *. :* * ** *: * .. : * * .** *:. : .... ..* **:: :. :**:* * :: . . : : * . . ::*:.:*:*. : . . * **:*:::.:* *: * : ::* . . . . .** . . ****: . :. :.* *:. :: ", "identical_positions": 79, "similar_positions": 100, "identity": "18.08%" }, { "cls_id": "homologset.agr.MGI:1860489", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q66H20-1", "uniprot_id": "PTBP2_RAT", "id": "Q66H20-1", "name": "Polypyrimidine tract-binding protein 2", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MDGIVTEVAVGVKRGSDELLSG-----------------------SVLSSPNSNMSG-MVVTANGNDSKKFKGEDKM-----------------------------------------------DGAPSRVLHIRKLPGEVTETEVIALGLPFGKVTNILMLKGKNQAFLELATEEAAITMVNYYSAVTPHLRNQPIYIQYSNHKELKTDNTLNQRAQVVLQAVTAVQTANTP--------LSGTTVSESAVTPAQ---------------------SPVLRIIIDNMYYPVTLDVLHQIFSKFGAVLKIITFTKNNQFQALLQYGDPVNAQQAKLALDGQNIYNACCTLRIDFSKLVNLNVKYNNDKSRDYTRPDLPSGDGQPALDPAIAAAFAKET-SLLAVPG-----------------ALSPLAI-------------PNAAAAAAAAAAGRVGMPGVSAGGN-TVLLVSNLNEEMVTPQSLFTLFGVYGDVQRVKILYNKKDSALIQMADGNQSQLAMNHLNGQKMYGKIIRVTLSKHQTVQLPREGLDDQGLTKDFGNSPLHRFKKPGSKNFQNIFPPSATLHLSNIPPSVAEEDLRTLFANTGGTVKAFKFFQ-DHKMALLQMATVEEAIQALIDLHNYNLGENHHLRVSFSKSTI", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q91Z31-1", "uniprot_id": "PTBP2_MOUSE", "id": "Q91Z31-1", "name": "Polypyrimidine tract-binding protein 2", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MDGIVTEVAVGVKRGSDELLSG-----------------------SVLSSPNSNMSG-MVVTANGNDSKKFKGEDKM-----------------------------------------------DGAPSRVLHIRKLPGEVTETEVIALGLPFGKVTNILMLKGKNQAFLELATEEAAITMVNYYSAVTPHLRNQPIYIQYSNHKELKTDNTLNQRAQVVLQAVTAVQTANTP--------LSGTTVSESAVTPAQ---------------------SPVLRIIIDNMYYPVTLDVLHQIFSKFGAVLKIITFTKNNQFQALLQYGDPVNAQQAKLALDGQNIYNACCTLRIDFSKLVNLNVKYNNDKSRDYTRPDLPSGDGQPALDPAIAAAFAKET-SLLAVPG-----------------ALSPLAI-------------PNAAAAAAAAAAGRVGMPGVSAGGN-TVLLVSNLNEEMVTPQSLFTLFGVYGDVQRVKILYNKKDSALIQMADGNQSQLAMNHLNGQKMYGKIIRVTLSKHQTVQLPREGLDDQGLTKDFGNSPLHRFKKPGSKNFQNIFPPSATLHLSNIPPSVAEEDLRTLFANTGGTVKAFKFFQ-DHKMALLQMATVEEAIQALIDLHNYNLGENHHLRVSFSKSTI", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9UKA9-1", "uniprot_id": "PTBP2_HUMAN", "id": "Q9UKA9-1", "name": "Polypyrimidine tract-binding protein 2", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MDGIVTEVAVGVKRGSDELLSG-----------------------SVLSSPNSNMSS-MVVTANGNDSKKFKGEDKM-----------------------------------------------DGAPSRVLHIRKLPGEVTETEVIALGLPFGKVTNILMLKGKNQAFLELATEEAAITMVNYYSAVTPHLRNQPIYIQYSNHKELKTDNTLNQRAQAVLQAVTAVQTANTP--------LSGTTVSESAVTPAQ---------------------SPVLRIIIDNMYYPVTLDVLHQIFSKFGAVLKIITFTKNNQFQALLQYGDPVNAQQAKLALDGQNIYNACCTLRIDFSKLVNLNVKYNNDKSRDYTRPDLPSGDGQPALDPAIAAAFAKET-SLLAVPG-----------------ALSPLAI-------------PNAAAAAAAAAAGRVGMPGVSAGGN-TVLLVSNLNEEMVTPQSLFTLFGVYGDVQRVKILYNKKDSALIQMADGNQSQLAMNHLNGQKMYGKIIRVTLSKHQTVQLPREGLDDQGLTKDFGNSPLHRFKKPGSKNFQNIFPPSATLHLSNIPPSVAEEDLRTLFANTGGTVKAFKFFQ-DHKMALLQMATVEEAIQALIDLHNYNLGENHHLRVSFSKSTI", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A5PM68-1", "uniprot_id": "A5PM68_DANRE", "id": "A5PM68-1", "name": "", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MDGIASDVAVGVKRSSDDLLSG-----------------------SLYSSPNS------SVTANGSDSKKLRVEDSM-----------------------------------------------DSPPSRVIHIRKLPNEVSETEVIALGLPFGKVTNILMLKGKNQAFLELGTEEAAVTMVNYYTAVTPQVRNVPVFIQYSNHKELKTDSALNQRAQAVLQAVSAVQEGGSP--------SSDM-ASKSVLTPAP---------------------SPVLRIIIDNMFYPVTLDVLQQIFSKFGTVMKIITFTKNNQFQALLQFSDPVNAQQAKLSLDGQNIYNSCCTLRIDFSKLVNLNVKYNNDKSRDYTRPELPAGDGQPPVDPSMAAALSKDSPSLLGTPSGMVTSYSSGGGFPSSLGAISPLS-----------------AAAAAAAAAGRVALSGHSVPG--GVLLVSNLNDEMVTPQSLFTLFGVYGDVQRVKILYNKKDSALIQMSDGNQAQLAMSHLNGQKMYGKIIRVTLSKHQTVQLPREGLDDQGLTKDFTSSPLHRFKKPGSKNFQNIFPPSATLHLSNIPDNVTEEDLRLLFSNSGGTVKAFKFFQ-DRKMSLLQMATAEEAIQALIDLHNYDMGRGHRLRVSFSKSTI", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A0R4IZG6-1", "uniprot_id": "A0A0R4IZG6_DANRE", "id": "A0A0R4IZG6-1", "name": "", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MDGIG-DVAVGVKRGSDELLSG-----------------------GMYNSPSSGLSSISDTTSNGSDSKKLRVEERVG----------------------------------------------DAPPSRVLHIRKLPNDVSEAEIIALGLPFGKVTNILTLKGKNQAFLELSTEEAAMTMVNYYSAVTPHVRSVPVYIQYSNHKELKTDNSS--------------QSGGTS--------TSGS-NSSDGSGSAS---------------------SPVLRIIIDNMFYPVTLDVLQQIFSKFGTVMKIITFTKNNQFQALLQYNDPACAQQAKVALDGQNIYNACCTLRIDYSKLVNLNVKYNNDKSRDYTRPELPAGDGQPALD--VAAALSKDSSSLLGKIP----------------GALSPLS-----------------AAAAAAAAAGRVALSGHSSSG--GVLLVSNLNEEMVTPHSLFTLFGVYGDVQRVKILFNKKDSALIQMADMNQAQLAMSHLNGQKMFSKIIRVTMSKHQTVQLPRDGLDDQGLTKDFTNSPLHRFKKPGSKNFQNIFPPSATLHLSNIPQDVTEEDLRVLFSNSGGTVKAFKFFQ-DHKMALIQMSTIEEAIQCLIDLHNYNMGNNHHLKVSFSKSTI", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A0B4K6W9-1", "uniprot_id": "A0A0B4K6W9_DROME", "id": "A0A0B4K6W9-1", "name": "", "aln": "MMSCPIPMPMPISSLHKSEFEPVNIGVKQMQLLHAPASTHPHPHPHQHPQHSAASAAAYQAMQVHQQQHQQQQQAAVFHHQVAAIAAQQQQQQQQAQVQHQQQMQQQFHYQAQAQAQAQAMLQTYMQLQVNSAVGVSTAPATPTKPVAAQIPGAISGPIAGPVPVSVPTQFFTAPSTPLTIIPAAAVASSAMFATAATPTSAATTPTNNVNNTVNLSAVSRTTTTTTKKQPQAVADAVLSAVGGNVGTAVGGGTISSLLGPEPLPIMPHHLPLASVRGCSSASSGCSSASSDCSMPSPTSLHLSSPKKVRIDEQYIYKLNYLRGSDELLSQAAVMAPASDNNNQDLATKKAKLEPGTVLAGGIAKASKVIHLRNIPNESGEADVIALGIPFGRVTNVLVLKGKNQAFIEMADEISATSMVSCYTVTPPQMRGRMVYVQFSNHRELKTDQGHNNSTAHSDYSVQSPASGSPLPLSAAANATSNNANSSSDSNSAMGILQNTSAVNAGGNTNAAGGPNTVLRVIVESLMYPVSLDILHQIFQRYGKVLKIVTFTKNNSFQALIQYPDANSAQHAKSLLDGQNIYNGCCTLRIDNSKLTALNVKYNNDKSRDFTNPALPPGEPGVDIMPTAGGLMNTNDLLLIAARQRPSLSVNGLG----APGVLPPFALGLGTPLTGGYNNALPNLAAFSLANSGALQTTAPAMRGYSNVLLVSNLNEEMVTPDALFTLFGVYGDVQRVKILYNKKDSALIQMAEPQQAYLAMSHLDKLRLWGKPIRVMASKHQAVQLPKEGQPDAGLTRDYSQNPLHRFKKPGSKNYQNIYPPSATLHLSNIPSSCSEDDIKEAFTSNSFEVKAFKFFPKDRKMALLQLLSVEEAVLALIKMHNHQLSESNHLRVSFSKSNI", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :..: :*...* .: . * * . .*..* .: : ...**.: :: . .*:*:*:*::*.: *:::****:***:***:* ********:*:. * :* :**. *:...*::*. :::*:***:*****. ... *. *.. .* ..***:*::.: ***:**:*:***.::* *:**:******.****:*: *. **:** ********.******* ***. ************:*.* **.*: : .. : .: *:. .:.*:: ** : * :* : .. : * ********:*****.:*****************:**********:: :*: ***.**: :::.* *** ****:****::* * ***:*: ..************:***:************ . :*:*:: *:... ******* *:**:*:*: : ***: .**.:**:::...::*:******.*", "identical_positions": 249, "similar_positions": 162, "identity": "27.61%" }, { "cls_id": "homologset.agr.MGI:1860490", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I6ALM7-1", "uniprot_id": "A0A8I6ALM7_RAT", "id": "A0A8I6ALM7-1", "name": "", "aln": "------VFLACRGR----RRGGKMYKFRDLTVEELKTVNMSFPHFRYSMDTYVFKDTSQKDLLNFTGTIPVMYQGKT-YNIPIRFWILDSHPFAPPIC------FLKPTANMEISVGKHVDAKGRIYLPYLQNWSHPKSVIVGLIKEMIAKFQEELPLYSVPSSNEAQQVDLLAYITKITEGVSDINSRGWTNHENKIPNKITVVGSGDLGIACTLAISAKGIADKLLLLDLSDG-TNQGTMDLDIFNLPNVEISKDLSASAHSKVVIFTANSLGGSESYLHAVQSNVDMFRALVPALGHYSQHAVLLVASQPVEIMSYVTWKLSTFPAARVMGIGCNLDSQRLQYIISSVLKAQTSGKEVWVVGEQGENKVCSWS----GQDGVMSPS----SQAQLSSRAMGLLKVKGQRSWSVGLSVADLLDTIINNKKKVHSVSTLAKGYYGLDNEVFLSLPCILGTSGVSEVLKT-AAEDAVTEALQTSASSIHGLQQQLKL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q3U1V6-1", "uniprot_id": "UEVLD_MOUSE", "id": "Q3U1V6-1", "name": "Ubiquitin-conjugating enzyme E2 variant 3", "aln": "------MEFDCEGV----RRLLGKYKFRDLTVEELKNVSVSFPHFRYSVDTYVFKDTSQKDLLNFTGTIPVMYQGKT-YNIPIRFWILDSHPFAPPIC------FLKPTANMEISVGKHVDAKGRIYLPYLQNWSHPKSAIVGLIKEMIAKFQEELPLYSIPSSNEAQQVDLLAYITKITEGVSDINSRGWTNHENKILNKITVVGSGDLGIACTLAISAKGIADKLLLLDLSDG-MSQGTMDLDIFNLPNVEISKDLSASAHSKVVIFTANSLGGSESYLHAVQSNVDMFRALVPALGHYSQHAVLLVASQPVEIMSYVTWKLSTFPATRVVGIGCNLDSQRLQYIITSVLKVQTSGKEVWVVGEQGENKVCSWS----GRDGVLSPS----SQAQLSSRAMELLKVKGQRSWSVGLSVADLVDTIINNKRKVHSVSTLAKGYYGLDNEVFLSLPCILGTGGVSEVIKTKAGEDTVTGTLQASASSIHALQQQLEL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8IX04-1", "uniprot_id": "UEVLD_HUMAN", "id": "Q8IX04-1", "name": "Ubiquitin-conjugating enzyme E2 variant 3", "aln": "------MEFDCEGL----RRLLGKYKFRDLTVEELRNVNVFFPHFKYSMDTYVFKDSSQKDLLNFTGTIPVMYQGNT-YNIPIRFWILDSHPFAPPIC------FLKPTANMGILVGKHVDAQGRIYLPYLQNWSHPKSVIVGLIKEMIAKFQEELPMYSLSSSDEARQVDLLAYIAKITEGVSDTNSKSWANHENKTVNKITVVGGGELGIACTLAISAKGIADRLVLLDLSEG-TKGATMDLEIFNLPNVEISKDLSASAHSKVVIFTVNSLGSSQSYLDVVQSNVDMFRALVPALGHYSQHSVLLVASQPVEIMTYVTWKLSTFPANRVIGIGCNLDSQRLQYIITNVLKAQTSGKEVWVIGEQGEDKVLTWS----GQEEVVSHT----SQVQLSNRAMELLRVKGQRSWSVGLSVADMVDSIVNNKKKVHSVSALAKGYYDINSEVFLSLPCILGTNGVSEVIKTTLKEDTVTEKLQSSASSIHSLQQQLKL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6DBY5-1", "uniprot_id": "UEVLD_DANRE", "id": "Q6DBY5-1", "name": "Ubiquitin-conjugating enzyme E2 variant 3", "aln": "------MDVNSEPV----KKVLSKYKFRDVAVEELQKVYRVYPDMKIMAGTYTSSDSLQKDLLKLVGNIPVVYQGRS-YNIPILLWLLDSFPFTPPIC------YLRPTSSMVIREGKHVDSKGRIHLPALHNWDHPKSSVNALLAEMIGKFEEEPPLGTKSSAHGDTPSNLLDYVSNLT--ITEGGNR--PDQE----VKVSVIGGGDLGIAAVLSIMAKSCVDKLVLIDIPENSTKGGTMDLEIFSLPKVEVSKDLSASAGSKVLVITANAWSDEQSYLSVVQTNVDMYRGIIPRLAQLSPNAVLVIASQPVDVMTHVAWRQSHLLPTQVIGVGCNLDSQRLSHIINISLVANNTGKQAWVIGELSENKVAVWGNMGPGTDQLQALTPVSNSTKPLMDRAFEMIKGRGQRSWSVGLSIADITHSIVTNQKKVHSVTTLAEGWGGIGSKVFLSLPCILGETGSTRLPGVALGSEDEMKLRESVACQVN-LFMQLRL", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P25604-1", "uniprot_id": "STP22_YEAST", "id": "P25604-1", "name": "Suppressor protein STP22 of temperature-sensitive alpha-factor receptor and arginine permease", "aln": "MSANGKISVPEAVVNWLFKVIQPIYNDGRTTFHDSLALLDNFHSLRPRTRVFTHSDGTPQLLLSIYGTISTGEDGSSPHSIPVIMWVPSMYPVKPPFISINLENFDMNTISSSLPIQEYIDSNGWIALPILHCWDPAAMNLIMVVQELMSLLHE-PPQDQAPSLPPKPNTQLQQ-------------------------------------EQNTPPLPPKPKSPHLKPPLPPPPPPQPASNALDLMDMDNTDISP----------------------------TNHHEMLQNLQTVVNELYREDVDYVADKILTRQTVMQESIARFHEIIAIDKN---HLRAVEQAIEQTMHSLNAQIDVLTANRAKVQQFSSTS------------------------------HVDDEDVNSIAVAKTDGLNQLYNLVAQDYALTDTIECLSRMLHRGTIPLDTFVKQG------------RELARQQFLVRWHIQRITSPLS-", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . : *: :..: : : :: .:. .* : **.: *.*.. :* : :.**: :*: . .*. **: : * . : :::*::* * ** *: *. . : :: *::. :.* * .* :* . .: .* :* . . .: *:::.: :.::* .: :* : : . : . . * :*.: : : : : : .:. . . : :. * : .: :. . .. ::. . : .: *:.:: :* . : . : :::: : : . :.* :: :: : * ", "identical_positions": 38, "similar_positions": 135, "identity": "7.65%" }, { "cls_id": "homologset.agr.MGI:1860493", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O55043-1", "uniprot_id": "ARHG7_RAT", "id": "O55043-1", "name": "Rho guanine nucleotide exchange factor 7", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MTDNANSQLVVRAKFNFQQTNEDELSFSKGDVIHVTRVEEGGWWEGTHNGRTGWFPSNYVREIKPSEKPVSPKSGTLKSPPKGFDTTAINKSYYNVVLQNILETEHEYSKELQSVLSTYLWPLQTSEKLSSANTSYLMGNLEEISSFQQVLVQSLEECTKSPEAQQRVGGCFLSLMPQMRTLYLAYCANHPSAVSVLTEHSEDLGEFMETKGASSPGILVLTTGLSKPFMRLDKYPTLLKELERHMEDYHPDRQDIQKSMTAFKNLSAQCQEVRKRKELELQILTEPIRSWEGDDIKTLGSVTYMSQVTIQCAGSEEKNERYLLLFPNLLLMLSASPRMSGFIYQGKLPTTGMTITKLEDSENHRNAFEISGSMIERILVSCNNQQDLHEWVEHLQRQTKVTSVSNPTIKP----------------------------------HSVPSHTLPSHPLTPSSKHADSKPVALTPAYHT---------------------------------------------------------------------------------------------------------------LPHPSHHGTPHTTISWGPLEPPKTPKPWSLSCLR---------------------------------------------PAPPLRPSAALCYKEDLSRSPKTMKKLLP----------------------KRKPERKPSDEEFAVRKSTAALEEDAQILKVIEAYCTSAKTRQTLN---------------------------------------------------------------------------SSSRKESAPQVLLPEEEKIIVEETKSNGQTVIEEK--------------------------------------------------------------------------------------------------------SLVDTVYALKDEVQELRQDNKKMKKSLEEEQRARKDLEKLVRKVLKNMNDPAWDETNL----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9ES28-1", "uniprot_id": "ARHG7_MOUSE", "id": "Q9ES28-1", "name": "Rho guanine nucleotide exchange factor 7", "aln": "MNSAEQTVTWLITLGVLESPKKTISDPEVFLQASLKDGVVLCRLLERLLPGTIEKVYPEPRNESECLSNIREFLRACGASLRLE---------------------TFDANDLYQGQNFNKVLSSLVTLNKVTADIGLGSDSVCARPS-SHRIKSFDSLGSQSSHSRTSKLLQSQYRSLDMTDNTNSQLVVRAKFNFQQTNEDELSFSKGDVIHVTRVEEGGWWEGTHNGRTGWFPSNYVREIKPSEKPVSPKSGTLKSPPKGFDTTAINKSYYNVVLQNILETEHEYSKELQSVLSTYLRPLQTSDKLSSANTSYLMGNLEEISSFQQVLVQSLEECTKSPEAQQRVGGCFLSLMPQMRTLYLAYCANHPSAVSVLTEHSEDLGEFMETKGASSPGILVLTTGLSKPFMRLDKYPTLLKELERHMEDYHPDRQDIQKSMTAFKNLSAQCQEVRKRKELELQILTEPIRSWEGDDIKTLGSVTYMSQVTIQCAGSEEKNERYLLLFPNLLLMLSASPRMSGFIYQGKLPTTGMTITKLEDSENHRNAFEISGSMIERILVSCTSQQDLHEWVEHLQKQTKVTSVSNPTIKP----------------------------------HSVPSHTLPSHPLTPSSKHADSKPVALTPAYHT---------------------------------------------------------------------------------------------------------------LPHPSHHGTPHTTISWGPLEPPKTPKPWSLSCLR---------------------------------------------PAPPLRPSAALCYKEDLSKSPKTMKKLLP----------------------KRKPERKPSDEEFAVRKSTAALEEDAQILKVIEAYCTSAKTRQTLNSTWQGTDLMHNHVLADDDQSSLDSLGRRSSLSRLEP----------------SDLSEDSEYDSIWTAHSYRMGSASRSRKESAPQVLLPEEEKIIVEETKSNGQTVIEEK--------------------------------------------------------------------------------------------------------SLVDTVYALKDEVQELRQDNKKMKKSLEEEQRARKDLEKLVRKVLKNMNDPAWDETNL----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q14155-4", "uniprot_id": "ARHG7_HUMAN", "id": "Q14155-4", "name": "Rho guanine nucleotide exchange factor 7", "aln": "MNSAEQTVTWLITLGVLESPKKTISDPEGFLQASLKDGVVLCRLLERLLPGTIEKVYPEPRSESECLSNIREFLRGCGASLRLELLFPPSQPPQHLVTTILLSASTFDANDLYQGQNFNKVLSSLVTLNKVTADIGLGSDSVCARPS-SHRIKSFDSLGSQSLHTRTSKLFQGQYRSLDMTDNSNNQLVVRAKFNFQQTNEDELSFSKGDVIHVTRVEEGGWWEGTLNGRTGWFPSNYVREVKASEKPVSPKSGTLKSPPKGFDTTAINKSYYNVVLQNILETENEYSKELQTVLSTYLRPLQTSEKLSSANISYLMGNLEEICSFQQMLVQSLEECTKLPEAQQRVGGCFLNLMPQMKTLYLTYCANHPSAVNVLTEHSEELGEFMETKGASSPGILVLTTGLSKPFMRLDKYPTLLKELERHMEDYHTDRQDIQKSMAAFKNLSAQCQEVRKRKELELQILTEAIRNWEGDDIKTLGNVTYMSQVLIQCAGSEEKNERYLLLFPNVLLMLSASPRMSGFIYQGKLPTTGMTITKLEDSENHRNAFEISGSMIERILVSCNNQQDLQEWVEHLQKQTKVTSVGNPTIKP----------------------------------HSVPSHTLPSHPVTPSSKHADSKPAPLTPAYHT---------------------------------------------------------------------------------------------------------------LPHPSHHGTPHTTINWGPLEPPKTPKPWSLSCLR---------------------------------------------PAPPLRPSAALCYKEDLSKSPKTMKKLLP----------------------KRKPERKPSDEEFASRKSTAALEEDAQILKVIEAYCTSAKTRQTLN---------------------------------------------------------------------------------STWQGTDLMHNHVLADDDQPSLDSLGRRS--------------------------------------------------------------------------------------------------------SLS------RLEPSDLSEDSDYDSIWTAHSYRMGSTSRKSCCSYISHQN-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M2BEZ3-1", "uniprot_id": "A0A8M2BEZ3_DANRE", "id": "A0A8M2BEZ3-1", "name": "", "aln": "MNPAEQTVTWLITLGVLESPKKTISDPDGFLQASLKDGVVLCRLLERLRPGTTDKIIQDPKNDSECLSNITEFLKGC-AVFRVEP---------------------FEAGDLLQGHNISRVLTTLVALNKVTADIGIGSDSVCTRHSSAHRIKSFESLASQSSLGRSSKLLHNQFRSLDMTDNSNAQLVVKARFNFQQTNEDELTFSKGDLISVTRTEEGGWWEGILNGKTGWFPSNYVKEVKGSDKQVSPKSGNLKSPPKGFDTASISKTYYNLVLQNILETETEYSRELQNLLTSYLRPLQMTERLSPADVSVILGNLEEISTFQQTLVQSLEDLTKLPELQQKVGGFFLNLMPQMRSLNVSYCSNHPSTVNVLTVHSEELGEFMEARGASVPGILTLTSGLSKPFMRLDRYPTLLKELERHMEEGHPDRTEIQKCMTAFKNLSAQCQEVRKRKELELQILAETIRLWEGEDIKTLGSVLYMSQAMVQNHGCEEKNERYLLLFPHVLLILSASPRMSGFIYQGKLPLSGMTVTPLEDCESHKDAFELSGSMFERLQVICYNKQDLHDWLEHLNRQTKHTTMAAPSMKP----------------------------------LTVPCHTLPSHPLTP-SRHGESRGLTVAPAYHT---------------------------------------------------------------------------------------------------------------LPHPSSHGTPHSTMMWGPLEPPKTQKPWSLSCLR---------------------------------------------PAPPLRPSAALCYKEDLSKSPKTMKKLLP----------------------KRKPERKPSDEEFALRKSTVALEEDAQILKVIEAYCTSAKTRQTLN---------------------------------------------------------------------------SRQWKDGSPALIVPGDEKFSVDELKSNGQTLLEEK--------------------------------------------------------------------------------------------------------SLVDVVYALRDEVQELKQDYKKMKKSLEEEQRARKDLERIVKKMLKNMNDPSWDETNL----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A8DZ19-1", "uniprot_id": "A8DZ19_DROME", "id": "A8DZ19-1", "name": "", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MDQPLVVQAEYSFMGSNNDELCFQKGDVITVTQREDGGWWEGTLNDKTGWFPSNYVNECKVQ----LPLTETIRPPEE-------IQEYRSVVLKDLLDSERAHVAELQGLLENFLEPMQQTQILSQDEYAQLMCNFVEIVRTHEDLLIQIEECN------DRVGKLFLTSAPLMKKVHQAYCAAHPKAIVILDKYKDELEKYMERQGAATPGLLVLTTGLSKPFRRLDKYSAMLQELERHMESSHPDRGDTQRSVAVYKDIAATCSATRRQKELELQVLTGPVRGWQGQELSTLGDIIHMGSVAVG----ADHRDRYFVLFPQTLLFLSVSQRMSAFIYEGKLPLTGIIVNRLEDTDALKNAFEISSPLIDRIVAVCQGPNEANKWVELLNANNPSLPMGIKRQLSNLSNSSLGHLNAAHLSQHLDSRGYCTRFSLCAYYSSPPCHVRPLRVTLPPSNYPATAPYANLSAHFARLVKGGGLRSAIVKMLLYPQARQSIDLKRIALRKRRCHKASAKLKDLNTNQDSGQSELERQDAIELPTDSESYDDDFEDDFLHSCDSDPFEYVQFYQNKRNDSMCNSTGTFVDHGTGARRHCSSINLIKLDSADTDEVLALNELKKESLVIGSRALRALARKSTTRNSSVHTSTATLELGVGGSITNCVEEEPILKVKPSFSLQQQSSDASSIFAARLGGAFTACENLASMPDDLSRESSIQEPPTPLPASPTERHSMPTIFVGNRFNHSKNTEVYVPTWRDRQEMQNQSVDAKQDEELHSSSIDLPAACLSAPDKLQAELLYNYDEILEKPLQLHRELTPFPGHNLNSDKRVSHKSDSPSTGNAKTDPNLATRSSSTTELCIDTTSKKRTTPSERSRDSIRRCISYQFLQMSNRPPPPPPPRRDPDLHLDTKCRCCENSQCPSPRSSDSGMAGSCTITSPDPPNPESYFPMEAAGHDMLDNVEPERFDVCGMFREKFLTPEATQDVVDLSEEQPQLSDEPTTPTNRKEEPTCITSAQVQVNTRSIFLPSSSSMDETNRNVPANNILFSSSSADQLEPQATFRSGMYAHWWKKERLPPEVVRGIAHAYNKSLPSKDSKDSGSVCSSCFCSLGASGYSEGALYCSVCQNCADYYNGSVTSTTNTTTTTSSASCPLCSEDEGMIAPTHDSSSLDCPICNGRIASGAEEGKQSEMDRRPDVAAIKPHTPTARRPSASHSQQHPGRQQQRREPQPPGVSGHQLDVASQTEPVVQPPSQLQSVHAHSASTTSSASTTTTKSAKSSGGIRPQIKFSPDTKQQDSSSTPGVIHGRQSSNSGSGSSSGGSGGNGGAKRKERKHKG", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : ***:*.:.* :*:*** *.***:* **: *:****** *.:*********.* * . * : .::.* : : * .:**:::*::* : *** :* .:* *:* :: ** : : :: *: ** :: *: .:*: . ::** **. * *:.: :**: **.:: :* :.::* ::** :**: **:*.**:****** ***:*.::*:*******. *.** : *:.::.:*:::* *. .*::******:*: .:* *:*:::.***.: :*... : ::.:**::***: **:**.* ***.***:**** :*: :. *** : ::***:*..:::*: . * . :: :.*:* *: :. .:. . : *.*. * : * *.: : . .*:.: : * : ::: *:...* : :*. *: * *: ..::. ::: * :.. : * :. * *:. .* : : : * *.* .: : ** :: .. : . . : ... . * :* :: . . . : : . ", "identical_positions": 175, "similar_positions": 218, "identity": "11.56%" }, { "cls_id": "homologset.agr.MGI:1860494", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q3B8Q1-1", "uniprot_id": "DDX21_RAT", "id": "Q3B8Q1-1", "name": "Nucleolar RNA helicase 2", "aln": "-MPGKLRSASKSESEGTEESMETLQKPSEKKTRKEKPKSKTDEATEGVEEAASS----------KVKAVKKKG-PSEDDVGPPKSKKAKKQEEEPQDDPASKSKTSKKKKEPLEKKAPSAKTKEMKA-EEPSE----EEADAPKPKKTKKGKEANGDVGEKSPGLKNGLSHP---------------------------------------------------------------------------KPDSSSTQAPGEES--ETEKEIPVEQKEGAFSNFPISEETVKLLKARGVNFLFPIQAKTFHHVYSGKDLIAQARTGTGKTFSFAIPLIEKLQGGLQERKRGRAPQVLVLAPTRELANQVSKDFSDITKKLSVACFYGGTPYGGQIERMRSGIDILVGTPGRIKDHLQNGKLDLTKLKHVVLDEVDQMLDMGFADQVEEILCVAYKKDSEDNPQTLLFSATCPHWVFNVAKKYMKSTYEQVDLIGKKTQKAAITVEHLAIKCHWTERAAVIGDVIRVYSGHQGRTIIFCETKKDAQELSQNTCIKQDAQSLHGDIPQKQREITLKGFRNGNFGVLVATNVAARGLDIPEVDLVVQSCPPKDVESYIHRSGRTGRAGRTGVCICFYQHKEEYQLAQVEQKAGIKFKRIGVPSATEIIKASSKDAIRLLDSVPPTAIGHFKQSAEKLIEEKGAVEALAAALAHISGATSVDQRSLINSQAGFVTMILRCSVEMPNISYAWKELKEQLGESIDAKVKGMVFLKGKLGVCFDVRTEAVTEIKEKWHDSRRWQLTVATEQPELEG---PPEGYRGGRGQRDGSRGSFRGQRGGSRNFRGQGQRGGSRNFRGQRPGGGNKSNRSPNKGQKRSFSKAFGQ", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9JIK5-1", "uniprot_id": "DDX21_MOUSE", "id": "Q9JIK5-1", "name": "Nucleolar RNA helicase 2", "aln": "-MPGKLRSGAKLGSDGAEESMETLPKPSEKKTRKEKTKSKTEEATEGMEEAVSS----------KAKKTNKKG-PSEDDVDPPKSRKAKKQEEEPQDDTASTSKTSKKKKEPLEKQADS-ETKEIIT-EEPSE----EEADMPKPKKMKKGKEANGDAGEKSPKLKNGLSQPSEEEADIPKPKKMKKGKEANGDAGEKSPKLKNGLSQPSEEEVDIPKPKKMKKGKEASGDAGEKSPRLKDGLSQPSEPKSNSSDAPGEESSSETEKEIPVEQKEGAFSNFPISEETVKLLKARGVNFLFPIQAKTFHHVYSGKDLIAQARTGTGKTFSFAIPLIEKLQGGLQERKRGRAPQVLVLAPTRELANQVSKDFSDITKKLSVACFYGGTPYGGQIERMRSGIDILVGTPGRIKDHLQNGKLDLTKLKHVVLDEVDQMLDMGFADQVEEILCVAYKKDSEDNPQTLLFSATCPHWVFNVAKKYMKSTYEQVDLIGKKTQKAAITVEHLAIKCHWTERAAVIGDVIRVYSGHQGRTIIFCETKKDAQELSQNTCIKQDAQSLHGDIPQKQREITLKGFRNGNFGVLVATNVAARGLDIPEVDLVVQSCPPKDVESYIHRSGRTGRAGRTGVCICFYQNKEEYQLAQVEQKAGIKFKRIGVPSATEIIKASSKDAIRLLDSVPPTAISHFKQSAEKLIEEKGAVEALAAALAHISGATSVDQRSLINSQAGFVTMILRCSIEMPNISYAWKELKEQLGESIDAKVKGMVFLKGKLGVCFDVRTEAVTEIQEKWHDSRRWQLTVATEQPELEG---PPDGYRGRMGQRDGSRGAFRGQRGGSRNFRGQGQRGGSRNFRGQRPGGGNR-------GQKRSFSKAFGQ", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9NR30-1", "uniprot_id": "DDX21_HUMAN", "id": "Q9NR30-1", "name": "Nucleolar RNA helicase 2", "aln": "-MPGKLRSDAGLESDTAMKKGETLRKQTEEKEKKEKPKSDKTEEIAEEEETVFP----------KAKQVKKKAEPSEVDMNSPKSKKAKKKEEPSQNDISPKTKSLRKKKEPIEKKVVSSKTKKVTKNEEPSE----EEIDAPKPKKMKKEKEMNGETREKSPKLKNGFPHP---------------------------------------------------------------------------EPDCNPSEAASEESNSEIEQEIPVEQKEGAFSNFPISEETIKLLKGRGVTFLFPIQAKTFHHVYSGKDLIAQARTGTGKTFSFAIPLIEKLHGELQDRKRGRAPQVLVLAPTRELANQVSKDFSDITKKLSVACFYGGTPYGGQFERMRNGIDILVGTPGRIKDHIQNGKLDLTKLKHVVLDEVDQMLDMGFADQVEEILSVAYKKDSEDNPQTLLFSATCPHWVFNVAKKYMKSTYEQVDLIGKKTQKTAITVEHLAIKCHWTQRAAVIGDVIRVYSGHQGRTIIFCETKKEAQELSQNSAIKQDAQSLHGDIPQKQREITLKGFRNGSFGVLVATNVAARGLDIPEVDLVIQSSPPKDVESYIHRSGRTGRAGRTGVCICFYQHKEEYQLVQVEQKAGIKFKRIGVPSATEIIKASSKDAIRLLDSVPPTAISHFKQSAEKLIEEKGAVEALAAALAHISGATSVDQRSLINSNVGFVTMILQCSIEMPNISYAWKELKEQLGEEIDSKVKGMVFLKGKLGVCFDVPTASVTEIQEKWHDSRRWQLSVATEQPELEG---PREGYGGFRGQREGSRG-FRGQRDGNRRFRGQ--REGSRGPRGQRSGGGNKSNRSQNKGQKRSFSKAFGQ", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A2R9YJN8-1", "uniprot_id": "A0A2R9YJN8_DANRE", "id": "A0A2R9YJN8-1", "name": "RNA helicase", "aln": "MRTSALRTSASVLSFPHVCCESSMSSRSSTSSMPSKSLPESEAERDHLMEDIHNGLQLLKKKKKKLKEQQQTAETDECESPAPKKRKMKISSDTTDLNGNTDTHTLKVKKKKIKLEEEEEETTSTLLEKKKKKKIKLEKEEMMEETNTLLEKKKKIKMEKEEEKMMNGDSHT-----------------------------------------------------------------------------HSTEPAASSTDSDSEQEKETP-EQREGAFSNFRISPNTIKLLQARGVSYLFDIQVKTFNAVYDGKDLIGQARTGTGKTFSFAVPLVEKLQSGDQERRRGRPPKVLVLAPTRELAIQVTKDFKDITRKLSVTCFYGGSSYNPQIDAIRSGIDVLVGTPGRIRDHLQNNKLDLSQLQHVVLDEVDQMLDMGFAEQVEEILSASYKKDAEQKPQTLLFSATCPSWVYDVAKKYMRSQFIHVDLIGKKTQKAATTVEHLAIACHWSQRASVIGDVIQVYSGSHGRTIVFCETKKEATELSLNTSIKQSAQSLHGDIPQKQREVTLKGFRNGSFEVLVATNVAARGLDIPEVDLVIQSSPPNDVESYIHRSGRTGRAGRTGICICFYQRKEESQLKFVEQKAGITFKRVGVPTAYDIIQSSSKDAVRFLDSVPAVAVGYFREAAQELIQQRGAVEALAAALAHISGATSLEQRSLINSEPGFSSMILSCSQEMHSISFAWRGLKEQLGEEIDQHISHMVFIKGKKGVCFDVPVSKLKEVQEKWQDSRRWTLSTATQLPELEQSLRPNSGFGNSGG--FGNRSGFGNRSGNRSGFGNRGGRGRSSGFRSSGRGGGGG--------QKRSFSRAFNY", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .. **: : * .:: . :. . .*. ... * * * ::.. ..* : .**.:* * ..: .: : . ::: : **: :: : . :*.. :: .: *: : : .: *: : . ::. : ** .:. ... . *.. :* * *:* * **:******* ** :*:***:.***.:** **.***: **.*****.*************:**:***:. *:*:***.*:*********** **:***.***:****:*****:.*. *:: :*.***:********:**:**.****::*:****************:******..:****:*::*********** **::******:* : :**********:* ******* ***::**:******:**** :****:******:* *** *:.***.**************:********.* ********************:**.**:*******************:******.*** ** *******.***:***:* :**::*****:*:*****..*:.:*:::*::**:::******************::*******: ** :*** ** ** .**:**: *******.** ::. ***:*** ****** . :.*::***:***** *:.**: **** * .*: . * *.*. * .: .. * .: * * . *.. ***. ******:**. ", "identical_positions": 435, "similar_positions": 198, "identity": "49.49%" }, { "cls_id": "homologset.agr.MGI:1860508", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9JI39-1", "uniprot_id": "ABCBA_MOUSE", "id": "Q9JI39-1", "name": "ATP-binding cassette sub-family B member 10, mitochondrial", "aln": "MRAPSARALLLIPRRGPAVRAWAPAVSSRIWLASEWTP----------LVRAWTS---LIHKPGSGLRFPAPLSG-LPGG----------VGQWATSSGARRCWVLAGPRAAHPLFARLQGAAATGVRD------------LGNDSQRRPAATGR----SEVWKLLGLVRPERGRLSAAVGFLAVSSVITMSAPFFLGRIIDVIYTNPSEG---------YGDSLTRLCAVLTCVFLCGAAANGIRVYLMQSSGQSIVNRLRTSLFSSILRQEVAFFDKTRTGELINRLSSDTALLGRSVTENLSDGLRAGAQASVGVGMMFFVSPSLATFVLSVVPPISVLAVIYGRYLRKLSKATQDSLAEATQLAEERIGNIRTIRAFGKEMTEVEKYTGRVDQLLQLAQKEALARAGFFGAAGLSGNLIVLSVLYKGGLLMGSAHMTVGELSSFLMYAFWVGLSIGGLSSFYSELMKGLGAGGRLWELLERQPRLPFNEGMVLDEKTFQGALEFRNVHFTYPARPEVSVFQDFSLSIPSGSVTALVGPSGSGKSTVVSLLLRLYDPNSGTVSLDGHDIRQLNPVWLRSKIGTVSQEPVLFSCSVAENIAYGADNLSSVTAQQVERAAEVANAAEFIRSFPQGFDTVVGEKGILLSGGQKQRIAIARALLKNPKILLLDEATSALDAENEHLVQEALDRLMEG--RTVLIIAHRLSTIKNANFVAVLDHG-KICEHGTHEELLLKPNGLYRKLMNKQS------------------------FLSYNGAEQFLEPARA--------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9NRK6-1", "uniprot_id": "ABCBA_HUMAN", "id": "Q9NRK6-1", "name": "ATP-binding cassette sub-family B member 10, mitochondrial", "aln": "MRGPPAWPLRLLEPPSPAEPGRLLPVAC-VWAAASRVPGSLSPFTGLRPARLWGAGPALLWGVGAARRWRSGCRGGGPGASRGVLGLARLLGLWARGPGSCRCGAFAGPGAPRLPRARFPGGPAAAAWAGDEAWRRGPAAPPGDKGRLRPAAAGL----PEARKLLGLAYPERRRLAAAVGFLTMSSVISMSAPFFLGKIIDVIYTNPTVD---------YSDNLTRLCLGLSAVFLCGAAANAIRVYLMQTSGQRIVNRLRTSLFSSILRQEVAFFDKTRTGELINRLSSDTALLGRSVTENLSDGLRAGAQASVGISMMFFVSPNLATFVLSVVPPVSIIAVIYGRYLRKLTKVTQDSLAQATQLAEERIGNVRTVRAFGKEMTEIEKYASKVDHVMQLARKEAFARAGFFGATGLSGNLIVLSVLYKGGLLMGSAHMTVGELSSFLMYAFWVGISIGGLSSFYSELMKGLGAGGRLWELLEREPKLPFNEGVILNEKSFQGALEFKNVHFAYPARPEVPIFQDFSLSIPSGSVTALVGPSGSGKSTVLSLLLRLYDPASGTISLDGHDIRQLNPVWLRSKIGTVSQEPILFSCSIAENIAYGADDPSSVTAEEIQRVAEVANAVAFIRNFPQGFNTVVGEKGVLLSGGQKQRIAIARALLKNPKILLLDEATSALDAENEYLVQEALDRLMDG--RTVLVIAHRLSTIKNANMVAVLDQG-KITEYGKHEELLSKPNGIYRKLMNKQS------------------------FISA--------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F1Q5K6-1", "uniprot_id": "F1Q5K6_DANRE", "id": "F1Q5K6-1", "name": "ATP-binding cassette sub-family B member 10, mitochondrial", "aln": "MYG----TMLRMTGFAIGKLQQCSITCCRSSTFHHWST---------RTSRTWSR---QVRKNGSFDICVLPVYK----------------GRNISKLSCLRTEGLFSPKHSRHIVALYSTSTDSNQTS---------KSVVNQESSAKTTADSLPVPSEDVKKLLQLAHPQRWRLTAAVGFLVISSTVTMSAPFFLGKVIDTIYTSPTED---------FSSSLTSLCLMLTGVFLCGGAANAARVYLMQISGQQIVRKLRESLFSSILKQELGFFDKTRTGELINRLSADTAIVGRCLTDNLSDGLRSLAQAGAGVGMMLYVSPSLAAFVLMVVPPIACLAVIFGRFLRSISRRTQDALAEATQLAEERISNLRTVRAFGKELTEVQKYSQKVDHIFELAKKEAVVSAGFYGVTGLSGNVIILSVLYKGGLLMASEAMTVGQLSSFLMYAFWVGISIAGFSSFYSELMKGLGAGTRLWELIDRKPEFPLNEGLVLTSELLKGELEFRNVSFAYPTRKDSPIFQDLSLHVPAGSVLAVVGSSGSGKSSLVSLLLRLYDPDSGIVSVDGHDIRDLNPYWLRSHIGTVSQEPVLFSCSIAENIAYGAPDPSQVTVEDIYRAAQIANAHDFIQEFPKGYDTVVGEKGVLLSGGQKQRVAIARALLKNPKILLLDEATSALDAENEFLVQEALERLMDG--RTVLIIAHRLSTIQSADSVAVLDQH-RVMEIGSHSQLLANDQGLFRKLMEKQA------------------------FLQAEQKQALLK------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P33311-1", "uniprot_id": "MDL2_YEAST", "id": "P33311-1", "name": "ATP-dependent permease MDL2, mitochondrial", "aln": "MLNGRLPLLRLGICRNMLSRPRLAKLPSIRFRSLVTPS--------------------SSQLIPLSRLCLRSPAV----------------GKSLILQSFRCNSSKTVPETSLPSASPISKGSARSAHA-----------------KEQSKTDDY----KDIIRLFMLAKRDWKLLLTAILLLTISCSIGMSIPKVIGIVLDTLKTSSGSDFFDLKIP-IFSLPLYEFLSFFTVALLIGCAANFGRFILLRILSERVVARLRANVIKKTLHQDAEFFDNHKVGDLISRLGSDAYVVSRSMTQKVSDGVKALICGVVGVGMMCSLSPQLSILLLFFTPPVLFSASVFGKQIRNTSKDLQEATGQLTRVAEEQLSGIKTVQSFVAEGNELSRYNVAIRDIFQVGKTAAFTNAKFFTTTSLLGDLSFLTVLAYGSYLVLQSQLSIGDLTAFMLYTEYTGNAVFGLSTFYSEIMQGAGAASRLFELTDRKPSISPTVG-HKYKP-DRGVIEFKDVSFSYPTRPSVQIFKNLNFKIAPGSSVCIVGPSGRGKSTIALLLLRYYNPTTGTITIDNQDISKLNCKSLRRHIGIVQQEPVLMSGTIRDNITYGLT--YTPTKEEIRSVAKQCFCHNFITKFPNTYDTVIGPHGTLLSGGQKQRIAIARALIKKPTILILDEATSALDVESEGAINYTFGQLMKSKSMTIVSIAHRLSTIRRSENVIVLGHDGSVVEMGKFKELYANPTSALSQLLNEKAAPGPSDQQLQIEKVIEKEDLNESKEHDDQKKDDNDDNDNNHDNDSNNQSPETKDNNSDDIEKSVEHLLKDAAKEANPIKITPQP", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P33310-1", "uniprot_id": "MDL1_YEAST", "id": "P33310-1", "name": "ATP-dependent permease MDL1, mitochondrial", "aln": "MIVR---MIRLCKGPKLLRSQFASASALYSTKSLFKPP--------------------MYQKAEINLIIPHR--------------------KHFLLRSIRLQSDIAQGKKSTKPTLKLSN--------------------------ANSKSSGF----KDIKRLFVLSKPESKYIGLALLLILISSSVSMAVPSVIGKLLDLASESDGEDEEGSKSNKLYGFTKKQFFTALGAVFIIGAVANASRIIILKVTGERLVARLRTRTMKAALDQDATFLDTNRVGDLISRLSSDASIVAKSVTQNVSDGTRAIIQGFVGFGMMSFLSWKLTCVMMILAPPLGAMALIYGRKIRNLSRQLQTSVGGLTKVAEEQLNATRTIQAYGGEKNEVRRYAKEVRNVFHIGLKEAVTSGLFFGSTGLVGNTAMLSLLLVGTSMIQSGSMTVGELSSFMMYAVYTGSSLFGLSSFYSELMKGAGAAARVFELNDRKPLIRPTIGKDPVSL-AQKPIVFKNVSFTYPTRPKHQIFKDLNITIKPGEHVCAVGPSGSGKSTIASLLLRYYDVNSGSIEFGDEDIRNFNLRKYRRLIGYVQQEPLLFNGTILDNILYCIPPEIAEQDDRIRRAIGKANCTKFLANFPDGLQTMVGARGAQLSGGQKQRIALARAFLLDPAVLILDEATSALDSQSEEIVAKNLQRRVER-GFTTISIAHRLSTIKHSTRVIVLGKHGSVVETGSFRDLIAIPNSELNALLAE--------------------------QQDEEGKGGVIDLDN------------------------------SVAREV---------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* : . . . .. : . : :*: * : : *: :: :*. : *: * .:* ::* . . :. : : .:: * .** *. ::: .: :* :** :. * *: *:*. :.*:**.**.:*: ::.:.:*:::*** :: . .*..** :* .*: .:: ..**: * ::*: :*. :: * : . *::***::. :*:::: * .*: :* : .::.:. . *.. . *: :.* *: .*::* * :: . :::*:*::*::*: :.* :: *:*:****:*:* **. *::** :*:* : . * . : : *::* *:**:* . :*:::.: : .*. . **.** ***:: **** *: :* : ....** .:* * ** *.***:*:. :: :** * : : . . . *: .**. :*::* :* ********:*:***:: .* :*:********* :.* : : : :. * : ********: : * **.: : * *.. :* . *: : . ", "identical_positions": 158, "similar_positions": 221, "identity": "18.92%" }, { "cls_id": "homologset.agr.MGI:1860511", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZIH3-1", "uniprot_id": "D3ZIH3_RAT", "id": "D3ZIH3-1", "name": "", "aln": "-------------------------------------MKRPRAPSGSDGESDGPIDVGQENDLSQMARPLTT--------------------PSPSQMQARKKRRGIIEKRRRDRINSSLSELRRLVPTAFEKQGSSKLEKAEVLQMTVDHLKMLHASGGAGF-FDARALAVDFRSIGFRECLTEVVRYLGVLEGPSSHADPVRIRLLSHLNSYAAEMEPSPTTTG-------------------------ALAFPVWPWSFLHSCPGLPSLSSQLAILGRVPGPVLPN---VSSPPYPISALRSAPVHRVPGTIPPAQRNLLPSRGVTSSQRAHPPERPAAPPPTALGVRAARS--IVPILPCSSPAAPGAGKSDDSASGSISSPSPLGPTGRPAGAVFYHSWVSEITEIGAF------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9DBX7-1", "uniprot_id": "HEYL_MOUSE", "id": "Q9DBX7-1", "name": "Hairy/enhancer-of-split related with YRPW motif-like protein", "aln": "-------------------------------------MKRPRAPSGSDGESDGPIDVGQENDLSQMARPLTT--------------------PSPSQMQARKKRRGIIEKRRRDRINSSLSELRRLVPTAFEKQGSSKLEKAEVLQMTVDHLKMLHASGGTGF-FDARALAVDFRSIGFRECLTEVIRYLGVLEGPSSHADPVRIRLLSHLKSYAAEMEPSPTTTS-------------------------ALAFPVWPWSFLHSCPGLPSLNSQLAILGRVPGPVLPS---ISSPPYPISALRSAPVHRPAGTIPPTRRNLLPSRGVTSTQRAHLPERPAAPPPTALDARAARS--IVPIPPCSPTTAPGAGKSDDNVSGSISSPCPSGPTGRPAGAVFYHSWVSEITEIGAF------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9NQ87-1", "uniprot_id": "HEYL_HUMAN", "id": "Q9NQ87-1", "name": "Hairy/enhancer-of-split related with YRPW motif-like protein", "aln": "-------------------------------------MKRPKEPSGSDGESDGPIDVGQEGQLSQMARPLST--------------------PSSSQMQARKKHRGIIEKRRRDRINSSLSELRRLVPTAFEKQGSSKLEKAEVLQMTVDHLKMLHATGGTGF-FDARALAVDFRSIGFRECLTEVIRYLGVLEGPSSRADPVRIRLLSHLNSYAAEMEPSPTPTG-------------------------PLAFPAWPWSFFHSCPGLPALSNQLAILGRVPSPVLPG---VSSPAYPIPALRTAPLRRATGIILPARRNVLPSRGASSTRRARPLERPATPVPVAPSSRAARSSHIAPLLQSSSPTPPGPTGSAAYVAVPTPNSSSPGPAGRPAGAMLYHSWVSEITEIGAF------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8AXV5-1", "uniprot_id": "HEYL_DANRE", "id": "Q8AXV5-1", "name": "Hairy/enhancer-of-split related with YRPW motif-like protein", "aln": "-------------------------------------MKRPHDYSSPDSDTDELIDVGQEDSYCPVTGSMSP--------------------GSTSQILARKKRRGIIEKRRRDRINHSLSELRRLVPSAFEKQGSSKLEKAEILQMTVDHLKLLHAMGGKGY-FDARALAVDYRTLGFRECVGEVVRYLSSLEGVES-SDPIGARLVSHLSHCASELDPLLQSPA-------------------------ALPFPPWPWASFPQLQAASPPASSTPFPPNARRDLAPHG-TATILGYPSPALRMGSLS-TQGTILNP--------ALTSVR--QLPSVPGHLHRLQQHSPEGRT------VPSSSSSSSNSSPPQISFRPFVPAGSPAG--GRRALSSSSKSAQAWGTEIGAF------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q7KM13-1", "uniprot_id": "HEY_DROME", "id": "Q7KM13-1", "name": "Hairy/enhancer-of-split related with YRPW motif protein", "aln": "MDHNMHVNAPSLHHWGYAAGPGVVMPGATATTPQSHWVPPPQSHHSAHSNHSHGHSQGHSHGIGSLKRTLSESDCDDLYSEESSKEQISPSEPGSCQLMSRKKRRGVIEKKRRDRINSSLTELKRLVPSAYEKQGSAKLEKAEILQLTVEHLKSLQSKTLDSLSYDPQRVAMDYHIIGFRECAAEVARYLVTIEGMDI-QDPLRLRLMSHLQYFVQQRELSAKSCASPGGWSPAAPSSSGYQPNCAAAPYQSYAAPANPGAYVSSYPTLSASPSQQAQQLGGRTSVSRTSGSAVTESLPSHDLHSDSSSQQQQQQQQQQQQQQQHQQQQHQQQQQRTQTTPQPTQQQHYTHDHSAVHSEQQVPTYIELTNSNRPAAIGSDSLSYSAAPQYPVSGLPGQDYNNSSVLQYATPNGAKPYRPWGAEMAY", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : *: ....: . . *:. : .:: ...*: :***:**:***:****** **:**:****:*:*****:******:**:**:*** *:: . :*.: :*:*:: :***** ** *** :** . **: **:***. . : : . . . . * * : . . .. .. . : * *: . : : . . : . . . .. . . :* : .. ", "identical_positions": 72, "similar_positions": 81, "identity": "16.9%" }, { "cls_id": "homologset.agr.MGI:1860512", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9R1C7-1", "uniprot_id": "PR40A_MOUSE", "id": "Q9R1C7-1", "name": "Pre-mRNA-processing factor 40 homolog A", "aln": "-----------------------------------------------------------------------------MRPGTGAERGGLMVSEMESQPPSRGPGDGERRLSGSNLCSSSWVSADGFLRRRPSMGHPGMHYAPMGMHPMGQRANMPPVPHGMMPQMMPP-MGGPPMGQMPGMMSSVMSGMMMSHMSQASMQPALPPGVNSMDVAAGAASGAKSMWTEHKSPDGRTYYYNTETKQSTWEKPDDLKTPAEQLLSKCPWKEYKSDSGKPYYYNSQTKESRWAKPKELEDLEGYQNTIVAGGLITKSNLHAMIKAEESSKQEECTTASTAPVPTTEIPTTMSTMAAAEAAAAVVAAAAAAAAAA---NANTSTTPTNTVG-SVPVAPEPEVTSIVATAVDNENTVTVSTEEQAQLANTTAIQDLSGDISSNTGEEPAKQETVSDFTPKKEEEESQPAKKTYTWNTKEEAKQAFKELLKEKRVPSNASWEQAMKMIIN-DPRYSALAK-LSEKKQAFNAYKVQTEKEEKEEARSKYKEAKESFQRFLENHEKMTSTTRYKKAEQMFGEMEVWN--AISERDRLEIYEDVLFFLSKKEKEQAKQLRKRNWEALKNILDNMANVTYSTTWSEAQQYLMDNPT-----FAEDEELQNMDKEDALICFEEHIRALEKEEEEEKQKTLLRERRRQRKNRESFQIFLDELHEHGQLHSMSSWMELYPTISSDIRFTNMLGQP----GSTALDLFKFYVEDLKARYHDEKKIIKDILKDKGFVVEVN----TTFEDFVAIISSTKRSTTLDAGNIKLAFNSLLEKAEAREREREKEEARKMKRKESAFKSMLKQATPPIELDAVWEDIRERFVKEPAFEDITLESERKRIFKDFMHVLEHECQHHHSKNKKHSKKSKKHHRKRSRSRSGSESDDDDSHSKKKRQRSESHSASERSS-SAESERSYKKSKKHKKKSKKRRHKSDSP-------------ESDTEREKDKKEKDRDSEKDRSRQRSESKHKSPKKKTGKDSGNWDTSGSELSEGELEKRRRTLLEQLDDDQ--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8I5ZVY5-1", "uniprot_id": "A0A8I5ZVY5_RAT", "id": "A0A8I5ZVY5-1", "name": "Pre-mRNA-processing factor 40 homolog A", "aln": "MQATPSEAGGESPQSCVSVSRSDWTVGKPVSLLAPLIPPRSSGQPLPFGPSGRQPLRSLLVGMCSGSGRRRSSLSPTMRPGTGAERGGLMVSEMESQPPSRGPGDGERRLSGSNLCSSSWVSADGFLRRRPSMGHPGMHYAPMGMHPMGQRANMPPVPHGMMPQMMPP-MGGPPMGQMPGMMSSVMSGMMMSHMSQASMQPALPPGVNSMDVAAGAASGAKSMWTEHKSPDGRTYYYNTETKQSTWEKPDDLKTPAEQLLSKCPWKEYKSDSGKPYYYNSQTKESRWAKPKELEDLE------------------AMIKAEESSKQEECTTTSTAPVPTTEIPTTMSTMAAAEAAAAVVAAAAAAAAAA---NANTSTTPTNTVG-SVPVAPEPEVTSIVATAVDNENTVTASAEEQAQLANTTALQDLSGDISSNTGEEPPKQETVTDFTPKKEEEESQPAKKTYTWNTKEEAKQAFKELLKEKRVPSNASWEQAMKMIIN-DPRYSALAK-LSEKKQAFNAYKVQTEKEEKEEARSKYKEAKESFQRFLENHEKMTSTTRYKKAEQMFGEMEVWN--AISERDRLEIYEDVLFFLSKKEKEQAKQLRKRNWEALKNILDNMANVTYSTTWSEAQQYLMDNPT-----FAEDEELQNMDKEDALICFEEHIRALEKEEEEEKQKTLLRERRRQRKNRESFQIFLDELHEHGQLHSMSSWMELYPTISSDIRFTNMLGQPVFSLGSTALDLFKFYVEDLKARYHDEKKIIKDILKDKGFVVEVN----TTFEDFVAIISSTKRSTTLDAGNIKLAFNSLLEKAEAREREREKEEARKMKRKESAFKSMLKQATPPIELDAVWEDIRERFVKEPAFEDITLESERKRIFKDFMHVLEHECQHHHSKNKKHSKKSKKHHRKRSRSRSGSDSDDDDSHSKKKRQRSESHSASEHSS-SAESERSYKKSKKHKKKSKKRRHKSDSP-------------ESDTEREKDKKEKDRESEKDRSRQRSESKHKSPKKKTGKDSGNWDTSGSELSEGELEKRRRTLLEQLDDDQ--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O75400-1", "uniprot_id": "PR40A_HUMAN", "id": "O75400-1", "name": "Pre-mRNA-processing factor 40 homolog A", "aln": "-----------------------------------------------------------------------------MRPGTGAERGGLMVSEMESHPPSQGPGDGERRLSGSSLCSGSWVSADGFLRRRPSMGHPGMHYAPMGMHPMGQRANMPPVPHGMMPQMMPP-MGGPPMGQMPGMMSSVMPGMMMSHMSQASMQPALPPGVNSMDVAAGTASGAKSMWTEHKSPDGRTYYYNTETKQSTWEKPDDLKTPAEQLLSKCPWKEYKSDSGKPYYYNSQTKESRWAKPKELEDLEGYQNTIVAGSLITKSNLHAMIKAEESSKQEECTTTSTAPVPTTEIPTTMSTMAAAEAAAAVVAAAAAAAAAAAAANANASTSASNTVSGTVPVVPEPEVTSIVATVVDNENTVTISTEEQAQLTSTPAIQDQSVEVSSNTGEETSKQETVADFTPKKEEEESQPAKKTYTWNTKEEAKQAFKELLKEKRVPSNASWEQAMKMIIN-DPRYSALAK-LSEKKQAFNAYKVQTEKEEKEEARSKYKEAKESFQRFLENHEKMTSTTRYKKAEQMFGEMEVWN--AISERDRLEIYEDVLFFLSKKEKEQAKQLRKRNWEALKNILDNMANVTYSTTWSEAQQYLMDNPT-----FAEDEELQNMDKEDALICFEEHIRALEKEEEEEKQKSLLRERRRQRKNRESFQIFLDELHEHGQLHSMSSWMELYPTISSDIRFTNMLGQP----GSTALDLFKFYVEDLKARYHDEKKIIKDILKDKGFVVEVN----TTFEDFVAIISSTKRSTTLDAGNIKLAFNSLLEKAEAREREREKEEARKMKRKESAFKSMLKQAAPPIELDAVWEDIRERFVKEPAFEDITLESERKRIFKDFMHVLEHECQHHHSKNKKHSKKSKKHHRKRSRSRSGSDSDDDDSHSKKKRQRSESRSASEHSS-SAESERSYKKSKKHKKKSKKRRHKSDSP-------------ESDAEREKDKKEKDRESEKDRTRQRSESKHKSPKKKTGKDSGNWDTSGSELSEGELEKRRRTLLEQLDDDQ--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VQK5-1", "uniprot_id": "Q9VQK5_DROME", "id": "Q9VQK5-1", "name": "", "aln": "----------------------------------------------------------------------------------------------MNVPPSVGNGGAP-----------------------PGR---GIGYTP---------------PGAIVPQFPPPGFGAPPP-------------------------PELAAAFGVMATST--------EWTEHKAPDGRPYYYNQNTKQSSWEKPEALMTPAELLHNQCPWKEYRSDTGKVYYHNVATKETCWEPPPEYVDMK------------------AKAKAEEAAAAAKAVAAMTS-----------SSLAGMVPPAALASILPAALPVA-------------------PRLPTPEIHSPLTPSS-NEN--SSSAMDQAMAATLAAIE-----------------------VPQQNAKKDDKSESAVVFKDKREAIESFKELLRDRNVPSNANWDQCVKIISK-DPRYAAFKN-LNERKQTFNAYKTQKIKDEREESRLKAKKAKEDLEQFLMSSDKMNSQMKYFRCEEVFAGTRTWT--AVPEPDRRDIYEDCIFNLAKREKEEARLLKKRNMKVLGELLESMTSINHATTWSEAQVMLLDNVA-----FKNDVTLLGMDKEDALIVFEEHIRTLEKEEDEEREREKKRMKRQQRKNRDSFLALLDSLHEEGKLTSMSLWVELYPIISADLRFSAMLGQS----GSTPLDLFKFYVENLKARFHDEKKIIREILKEKAFVVQAK----TSFEDFATVVCEDKRSASLDAGNVKLTYNSLLEKAEAIEKERMKEEVRRLRKLENEIKNEWLEAN--VSVAEPYESAKKLVEHLEAFALYEKEIGVEKIWEDFVKESEDACSHHHSRSRKSKKNKKHKKRVRSVSRSDIENEHIEVE-KSKRRRSKTRSHSLTSIGSIESEKLLKKKKKRKNKLRGSSCESDVPGIQSPGTQALLQNDSNSHSPAKKKKKEKRAKKDKRHNRHNRSGTPLSPAQSVESSGSRNEELTLSDGELESKRAALLAQLSEQLDE", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P33203-1", "uniprot_id": "PRP40_YEAST", "id": "P33203-1", "name": "Pre-mRNA-processing protein PRP40", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSIWKEAKDASGRIYYYNTLTKKSTWEKPKELISQEELLLRENGWKAAKTADGKVYYYNPTTRETSWTIP-------------------------AFEKKVEP--------------------------------------------------------------------IAEQKHDTVSHAQVNGNRIALTAGEKQEPGRTINEE--------------------------ESQYANNSKLLNVRRRTKEEAEKEFITMLKENQVDSTWSFSRIISELGTRDPRYWMVDDDPLWKKEMFEKYLSNRSADQLLKEHNETSKFKEAFQKMLQNNSHIKYYTRWPTAKRLIADEPIYKHSVVNEKTKRQTFQDYIDTLIDTQKESKKKLKTQALKELREYLNGIITTSSSETFITWQQLLNHYVFDKSKRYMANRHFKVLTHEDVLNEYLKIVNTIENDLQNKLNELRLRNYTRDRIARDNFKSLLREVP--IKIKANTRWSDIYPHIKSDPRFLHMLGRN----GSSCLDLFLDFVDEQRMYIFAQRSIAQQTLIDQNFEWNDADSDEITKQNIEKVLENDRKFDKVDKEDISLIVDGLIKQRNEKIQQKLQNERRILEQK-----------------------------------------------KHYFWLLLQRTYTKTGKPKPSTWDLASKELGESLEYKALGDED------NIRRQIFEDFKPESSAPTAESATANLTLTASKKRHLTPAVELDY---------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *.* * ..** **** **:*:****. * : * * : ** :: ** **:* *:*: * * * * *. : . :: * * : :: :: : :. .: . *.** : * :*::..* *. .:.: :. : . **** . . :*: *: * : :: : : : .: ** ::::* . .::. :: .:.::. :. .: * : : ::* : * . :**. : *:.: : * : *:.: . . : *: * * . : : : : :**.* : : :.::*:: ::: :. * ::* *:.* :* .: :: : : * ::** *.:* ** ***: **: **** :*:: : . ::.* :: * :: * : : ::: :: . :: .:* ::.* :.*::: : ::: ::* * :.: :.:. . : .: : . . :. .* . . .:. . *:: . * : ** . . *:: : * ", "identical_positions": 104, "similar_positions": 207, "identity": "9.74%" }, { "cls_id": "homologset.agr.MGI:1860513", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q6ZQ03-1", "uniprot_id": "FNBP4_MOUSE", "id": "Q6ZQ03-1", "name": "Formin-binding protein 4", "aln": "--------------------------MMGKKSRAVPGRRPILQLSPPGPRSSTPGRDPDPDPDPEADSTAAATSQSAPAAATAAAATSPAVPASAAPEDSPSEDEQEVVVEVPNVVQNPPTPVMTTRPTAVKATGGLCLLGAYADSDDDESDVSEKTAQSKEANGNQATDIDSTLANFLAEIDAIT-APQPAAPVVASAPPPTPPRPEPKEAATPALSPTASNGSDTAQTPGWHYDTQCSLAGVEIEMGDWQEVWDENTGCYYYWNTQTNEVTWELPQYLATQVQGLQHYQPSSVTGTEAAFVVNTDMYTKERTTAASSSKSGPVITKREVKK-EVNEGIQALSNSEEERKGVAAALLAPLLPEGVKEEEERWRRKVICKEADPVSETKETSTASEETGPSIKPPEVMMDGTEDPSQEELCSVVQSGESEEEEEEEEQDTLELELALERKKAELRALEEGDGSVSGSSPRSDISQPASQDGVRRIMSKRGKWK-MFVRATSPESTSRSSSKTGRDSPENGETAIGAEDSEKIDEISDKETEVEESSEKIKVQLAPKVEEEQDLKFQIGELANTLTSKFEFLGINRQSISNFHMLLLQTETRIADWREGALNGNYLKRKLQDAAEQLKQYEINATPKGWSCHWDRDHRRYFYVNEQSGESQWEFPDGEEEEE-SQTKEVRDESLPKLTVKDKTCTDPNSTESSENPTGSLCKESFSGQVSSS-LMPLTPFWTLLQSNVPVLQPPLPLEMPPPPPPPPESPPPPPPPPPPPPPLEDGEIQEVEMEDEGSEEPPAPGTEEDTPLKPSTQTTAVTSQSLVDSTASSPPSNKAVKRKAPEMSTSVVQRSATIGSSPVLYSQSAIAAGHQAVGMAHQAVGMAHQAVSASHAAAAGVGHQARGMSLQSNYLGLAAAPALMSYAECSVPIGVTTPSLQPAQARGTMAAPAVVEPPPPPPPPPTPTPPPPPPAPKVPPPEKTRKGKKDKAKKSKTKMPSLVKKWQSIQRELDEEDNSSSSEEDRESTAQKRIEEWKQQQLVSGLAERNANFEALPEDWRAR-LKRRKMAPST", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "F1MAK1-1", "uniprot_id": "F1MAK1_RAT", "id": "F1MAK1-1", "name": "Formin-binding protein 4", "aln": "MNIDYAPGRRAPAPLICRRSLLALGLVMGKKSRAVPGRRPILQLSPPGPRSSTPGRDPDPDPDPETDSTAAATSQSVPAAATAAAATSPAVPATAAPEDSPSEDEQEVVVEVPNVVQNPPKPVMPTRPTTVKATGGLCLLGAYADSDDDENDISEKTAQSKESNGNQSTDIDSTLANFLAEIDAIT-APQPVAPVVASAPPPTPPRPEPKEAATPALSSAASNGTDAAQTAGWHYDTQCSLAGVEIEMGDWQEVWDENTGCYYYWNTQTNEVTWELPQYLATQVQGLQHYQTSSVTGTEAAFVVNTDIYAKEKMIPASSNKSGPVIAKREVKK-EVNEGIQALSNSEEERKGVAAALLAPLLPEGVKEEEERWRRKVICKEADPVSEAKETSTAAEETGPSIKPPEVAMDSTEDPSQEDLCSVVQSGESEEEEEEE-QDTLELELALERKKAELRALEEGDGSVSGSSPRSDISQPASQDGMPRIMSKRGKWK-MFVRATSPESTSRSSSKTGRETPENGETAIGAEDSEKINENSDKEAEVEESSEKIKVQIAPKVEEEQDLKFQIGELANTLTSKFEFLGINRQSISNFHMLLLQTETRIADWREGALNGNYLKRKLQDAAEQLKQYEINATPKGWSCHWDRDHRRYFYVNEQSGESQWEFPDGEEEEE-SQAQEVRDESLPKLTEKDKTCTDSNSAESSENSTGSLCKESFSGQVSSS-LMPLTPFWTLLQSNVPVLQPPLPLEMPPPPPPPPESPPPPPPPPPPPPPLEDGEIQEVEMEDEGSEEPPAPGTEEDTPLKPSTQTTVVTSQSSVDSTASSPPSTKAVKRKAPEISTAVVQRSATIGSSPVLYSQSAIAAGHQAVGMAHQAVSVSH--------AAAGMGHPTRGMSLQSNYLGLAAAPAILSYAECSVPIGVTTPSLQPAQARGTVAAPAVVEPPPPPPPPPTSTPPPPPPAPKGPPPEKTRKGKREKAKKSKTKMPSLVKKWQSIQRELDEEDNSSSSEEDRESTAQKRIEEWKQQQLVSGLAERNANFEALPEDWRAR-LKRRKMAPNT", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8N3X1-1", "uniprot_id": "FNBP4_HUMAN", "id": "Q8N3X1-1", "name": "Formin-binding protein 4", "aln": "---------------------------MGKKSRAVPGRRPILQLSPPGPRGSTPGRDPEPEPDTEPDSTAAVPSQPAPSAATT---TTTAVTAAAASDDSPSEDEQEAVQEVPRVVQNPPKPVMTTRPTAVKATGGLCLLGAYADSDDDDNDVSEKLAQSKETNGNQSTDIDSTLANFLAEIDAIT-APQPAAPVGASAPPPTPPRPEPKEAATSTLSSSTSNGTDSTQTSGWQYDTQCSLAGVGIEMGDWQEVWDENTGCYYYWNTQTNEVTWELPQYLATQVQGLQHYQPSSVPGAETSFVVNTDIYSKEKTISVSSSKSGPVIAKREVKK-EVNEGIQALSNSEEEKKGVAASLLAPLLPEGIKEEEERWRRKVICKE-EPVSEVKETSTTVEEATTIVKPQEIMLDNIEDPSQEDLCSVVQSGESEEEEEQD---TLELELVLERKKAELRALEEGDGSVSGSSPRSDISQPASQDGMRRLMSKRGKWK-MFVRATSPESTSRSSSKTGRDTPENGETAIGAENSEKIDENSDKEMEVEESPEKIKVQTTPKVEEEQDLKFQIGELANTLTSKFEFLGINRQSISNFHVLLLQTETRIADWREGALNGNYLKRKLQDAAEQLKQYEINATPKGWSCHWDRDHRRYFYVNEQSGESQWEFPDGEEEEEESQAQENRDETLAKQTLKDKTGTDSNSTESSETSTGSLCKESFSGQVSSSSLMPLTPFWTLLQSNVPVLQPPLPLEMPPPPPPPPESPPPPPPPPPP---AEDGEIQEVEMEDEGSEEPPAPGTEEDTPLKPSAQTTVVTSQSSVDSTISSSSSTKGIKRKATEISTAVVQRSATIGSSPVLYSQSAIATGHQAAGIGNQATGIGHQTIPVS-LPAAGMGHQARGMSLQSNYLGLAAAPAIMSYAECSVPIGVTAPSLQPVQARGAVPTATIIEPPPPPPPP----PPPPPPAPKMPPPEKTKKGRKDKAKKSKTKMPSLVKKWQSIQRELDEEDNSSSSEEDRESTAQKRIEEWKQQQLVSGMAERNANFEALPEDWRAR-LKRRKMAPNT", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F1QGN0-1", "uniprot_id": "F1QGN0_DANRE", "id": "F1QGN0-1", "name": "", "aln": "---------------------------MGKKTRAGTGRRTILQLSPPGPNRSATG--------TAREDGAASGSE----------------DETDGNTDGQREANVNVVMKTP----------------AVKATQGLSLLGAYEDSEDED-----AVENASKAKHNQSGDIDSTLANFMAEIDAITTQPTDESGTEPSAPVPTPPRPEPK------TDPQAQNGP----AQEFQYNTQYSLAGAGLEMGDWQEVWDENTGCYYYWNTQTNEVAWELPHYLADQMQNLHYSGSSSVNGNGVAHSS----YPEPQSTAVAP------AAKRELKKKDVIESVVALTSEEEERRGVAATLLAPLIPEEVKEAEEKWRKKTLGMEETPEAAPEQE----KDTIPFLDSPAIRDTESQNNQRSRNQSAESSDQEEEEQEED---TMELELALERKKAELRALEEGDASAGGSSPCS----EASQDGPRTLLLKKNKWKTAFLRAPSPDSSSRGSDKAGWATPEQSDTAH-SKPAEKQGEDDENEKPVSKALQ----------KEEEDLKFQIGELANTLTSKMEFLGIDKKAISNFQLLLLQTETRIADWREGALNGSYLRRRLQEAAEHIKHYELNATPKGWSCHWDREHRRYFYMNERTSASQWEFPVGGEEEE------------AKPPLPSATAHGDSSQPSAETTG------VVTGDVQSYWMVPPPP-QPPLPPLPPEHPPPPPTEQPPPPPPPPESPPPPPPPPLE----DDGEIEEVEMEDEESE-PPAPGTEEFKAAEAAALGLAARAQ----------------KRKA--LGSVPLPSMATIGSSPILYTQTIATPAPLLVG---------------------------------SAYWGMTAAIAPPLPTESIVPP---MPALPP-------------QPPPPVSQP----PPPLEPISKVLT-DKTKKLKKEKAKKSKTKMPSLVKKWQSIQKELDEEEKSSSSDEDRDQLNNRRIEEWKQQQLSTGKAGKNANFEALPDDWRERLLKKRKMMQSS", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ****:** .***.*********. *:.* . :. ** *: : . *. * : :.* :.* :**** **.***** **:*:: ::.::: **: *********:******* * : . .*** ********* .. :.**. : ::*:** ****. :**************************:****:*** *:*.*:: .*** * .:. *.: : ..:. :***:** :* *.: **:..***::****:*****:** :** **:**:*.: * * : :: ::: . :.. : :: .:. *. .*.:.***:*:: *:****.***************.*..**** * ***** :: *:.*** *:**.**:*:**.*.*:* :**:.:** :: :** .* .::* *.:: : :**:****************:*****::::****::*******************.**:*:**:***::*:**:*************:******:**::. ****** * **** .* . . * . .* *:*.. .:*:*.* ::* .* . * . * ** * * ****************** :****:******* ** ******** .. :.:: .. :* **** :.: : *******:**:*: :.. .* * * *::** * :*. ** *:* * :**** . * *** * .* . :**:* :::********************:*****::****:***:. ::********** :* * :********:*** * **:*** .:", "identical_positions": 461, "similar_positions": 223, "identity": "43.37%" }, { "cls_id": "homologset.agr.MGI:1860517", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O88451-1", "uniprot_id": "RDH7_MOUSE", "id": "O88451-1", "name": "Retinol dehydrogenase 7", "aln": "MWLYLVALVGLWTLLRFFRERQVVSHLQDKYVFITGCDSGFGNLLARQLDRRGMRVLAACLTEKGAEQLRNKTS-DRLETVILDVTKTESIVAATQWVKERVGNRGLWGLVNNAGICV-FAINEWLKKEDFANILDVNLLGMIEVTLSMLPLVRKARGRVVNISSSMGRVSL-CGGGYCISKYGVEAFSDSLRREISYFGVKVAIIEPGGFRTNVSNYERLSHSIEKLWDQTSSEVKEVYDKNFLDSYIKAIQSLTDTCSDDLSVVTDCMEHALTACHPRTRYSAGWDAKLFYLPLSYMPTFLVDAMLYWSSVKPAQAL-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P55006-1", "uniprot_id": "RDH7_RAT", "id": "P55006-1", "name": "Retinol dehydrogenase 7", "aln": "MWLYLLALVGLWNLLRLFRERKVVSHLQDKYVFITGCDSGFGNLLARQLDRRGMRVLAACLTEKGAEQLRSKTS-DRLETVILDVTKTESIVAATQWVKERVGNRGLWGLVNNAGISVPMGPNEWMRKKDFASVLDVNLLGVIEVTLNMLPLVRKARGRVVNIASTMGRMSL-LGGGYCISKYGVEAFSDSLRRELTYFGVKVAIIEPGGFKTNVTNMERLSDNLKKLWDQATEEVKEIYGEKFRDSYMKAMESLVNMCSGDLSLVTDCMEHALTSCHPRTRYSAGWDAKFFYLPMSYLPTFLSDAVIYWGSVKPARAL-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O75452-1", "uniprot_id": "RDH16_HUMAN", "id": "O75452-1", "name": "Retinol dehydrogenase 16", "aln": "MWLYLAVFVGLYYLLHWYRERQVLSHLRDKYVFITGCDSGFGKLLARQLDARGLRVLAACLTEKGAEQLRGQTS-DRLETVTLDVTKTESVAAAAQWVKECVRDKGLWGLVNNAGISLPTAPNELLTKQDFVTILDVNLLGVIDVTLSLLPLVRRARGRVVNVSSVMGRVSL-FGGGYCISKYGVEAFSDSLRRELSYFGVKVAMIEPGYFKTAVTSKERFLKSFLEIWDRSSPEVKEAYGEKFVADYKKSAEQMEQKCTQDLSLVTNCMEHALIACHPRTRYSAGWDAKLLYLPMSYMPTFLVDAIMYWVSPSPAKAL-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P40471-1", "uniprot_id": "AYR1_YEAST", "id": "P40471-1", "name": "NADPH-dependent 1-acyldihydroxyacetone phosphate reductase", "aln": "--------------------MSELQSQPKKIAVVTGASGGIGYEVTKELARNGYLVYACARRLEPMAQLAIQFGNDSIKPYKLDISKPEEIVTFSGFLRANLPDGKLDLLYNNAGQSCTFPALDAT-DAAVEQCFKVNVFGHINMCRELSEFLIKAKGTIVFTGSLAGVVSFPFGSIYSASKAAIHQYARGLHLEMKPFNVRVINAITGGVATDIADKRPLPETSIYNFPEGR-EAFNSRKTMAKDNKPMPADAYAKQLVKDILSTSDPVDVYRGTFANIMRFVMIFVP-YWLLEKGLSKKFKLDKVNNALKSKQKNKDD", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . :. .* ..:**...*:* ::::* .* * *.. : ** : . * ::. **::*.*.:.: : ::: : : * * **** . : . . :.**::* *:: .: :: :*:* :* .* * :*: *. *. ** .:. :: .*: *:. *.*:* .* . * ::. . : .. : . *. : . . : . *: .:: :: : *: : . * . .* * : . . . ", "identical_positions": 49, "similar_positions": 103, "identity": "15.31%" }, { "cls_id": "homologset.agr.MGI:1860603", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O14455-1", "uniprot_id": "RL36B_YEAST", "id": "O14455-1", "name": "Large ribosomal subunit protein eL36B", "aln": "MAVKTGIAIGLNKGKKVT------------------------QMTPAPKISYKK-GAASNRTKFVRSLVREIAG--------LSPYERRLIDLIRNSGEKRARKVAKKRLG-SFTR------AKAKVEEMNNIIAASRRH--------", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P05745-1", "uniprot_id": "RL36A_YEAST", "id": "P05745-1", "name": "Large ribosomal subunit protein eL36A", "aln": "MTVKTGIAIGLNKGKKVT------------------------SMTPAPKISYKK-GAASNRTKFVRSLVREIAG--------LSPYERRLIDLIRNSGEKRARKVAKKRLG-SFTR------AKAKVEEMNNIIAASRRH--------", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "A0ABK0LZ43-1", "uniprot_id": "A0ABK0LZ43_RAT", "id": "A0ABK0LZ43-1", "name": "60S ribosomal protein L36", "aln": "MALRYPMAVGLNKGHKVT------------------------KNVSKPRHSRRR-GRLTKHTKFVRDMIREVCG--------FAPYERRAMELLKVSKDKRALKFIKKRVG-THIR------AKRKREELSNVLAAMRKAAAKKD---", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "D3ZZ95-1", "uniprot_id": "D3ZZ95_RAT", "id": "D3ZZ95-1", "name": "60S ribosomal protein L36", "aln": "MALRYPMAVGLNKGHKVT------------------------KNVSKPRHSRRRRGRLTKHTKFVRDMIREVCG--------FAPYERRAMELLKVSKDKRALKFIKKRVG-THIR------AKRKREELSNVLAAMRKAAAKKD---", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P47964-1", "uniprot_id": "RL36_MOUSE", "id": "P47964-1", "name": "Large ribosomal subunit protein eL36", "aln": "MALRYPMAVGLNKGHKVT------------------------KNVSKPRHSRRR-GRLTKHTKFVRDMIREVCG--------FAPYERRAMELLKVSKDKRALKFIKKRVG-THIR------AKRKREELSNVLAAMRKAAAKKD---", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "F1M706-1", "uniprot_id": "F1M706_RAT", "id": "F1M706-1", "name": "60S ribosomal protein L36", "aln": "MALRYPMAMGLNKGHKVT------------------------KNVSKPRHSRRR-GRLTKHTKFVRDMIREVCG--------FAPYERRAMELLKVSKDKRALKFIKKKVG-THIR------AKRKREELSNVLAAMRKAAAKKD---", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "D4A1Q0-1", "uniprot_id": "D4A1Q0_RAT", "id": "D4A1Q0-1", "name": "Large ribosomal subunit protein eL36", "aln": "MALRYPMAVGLNKGHKVT------------------------KNVSKPRHSRRR-GRLTKHTKFVRDMIREVCG--------FAPYQRRAMELLKVSKDKRALKFIKKRVG-THIR------AKRKREELSNVLAAMRKAAAKD----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "M0RCN1-1", "uniprot_id": "M0RCN1_RAT", "id": "M0RCN1-1", "name": "Large ribosomal subunit protein eL36", "aln": "MALRYPMAVGLNKSHKVT------------------------KNVSKTRHSRRR-GRLTKHTKFVRDMIPEVCG--------FAPYVRRTMELLKVSKDKRALKFIKKRVG-THIR------AKRKREELSNVLAAMRKD--------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q6Q415-1", "uniprot_id": "RL36_DANRE", "id": "Q6Q415-1", "name": "Large ribosomal subunit protein eL36", "aln": "MVVRYPMAVGLNKGHKVT------------------------KNVSKPKHSRRR-GRLTKHAKFARDLIREVCG--------FAPYERRAMELLKVSKDKRALKFIKKRVG-THIR------AKRKREELSNTLAAMRKAAAKKE---", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P49630-1", "uniprot_id": "RL36_DROME", "id": "P49630-1", "name": "Large ribosomal subunit protein eL36", "aln": "MAVRYELAIGLNKGHKTSKIRN--------------VKYTGDKKVKGLRGSRLK-NIQTRHTKFMRDLVREVVG--------HAPYEKRTMELLKVSKDKRALKFLKRRLG-THIR------AKRKREELSNILTQLRKAQTHAK---", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "C0HME6-1", "uniprot_id": "ALT36_HUMAN", "id": "C0HME6-1", "name": "RPL36 alternative reading frame protein", "aln": "MASEAEGAGTRGSGPRELSRYSPPPLLPVAVRSHGPTLPYGRGPQQGPQSDQEREQAQAQPTPRASDQTHQVRAGHDSGGVWLCPVRAARHGVTEGLQGQTGPQIYQEKGGDAHPRQEEAGGAEQRTGRHEESCCQERLSPSPALSLK", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*. . * ... : : . : :. : . :: . .* : . : . :. :.: * :. * *: : . .: * ", "identical_positions": 7, "similar_positions": 33, "identity": "4.73%" }, { "cls_id": "homologset.agr.MGI:1860604", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P20595-1", "uniprot_id": "GCYB1_RAT", "id": "P20595-1", "name": "Guanylate cyclase soluble subunit beta-1", "aln": "MYGFVNHALELLVIRNYGPEVWEDIKKEAQLDEEGQFLVRIIYDDSKTYDLVAAASKVLNLNAGEILQMFGKMFFVFCQESGYDTILRVLGSNVREFLQNLDALHDHLATIYPGMRAPSFRCTDAEKGKGLILHYYSEREGLQDIVIGIIKTVAQQIHGTEIDMKVIQQRSE------------------------------------------------------------------------------------------------ECD----------------------HTQFLIEEK----ESKEEDFYEDLDRFEENGTQDSRISPYTFCKAFPFHIIFDRDLVVTQCGNAIYRVLPQLQPGKCSLLSVFSLVRPHIDISFHGILSHINTVFVLRSKEGLLDVEKLECEDELTGAEISCLRLKGQMIYLPEADSILFLCSPSVMNLDDLTRRGLYLSDIPLHDATRDLVLLGEQFREEYKLTQELEILTDRLQLTLRALEDEKKKTDTLLYSVLPPSVANELRHKRPVPAKRYDNVTILFSGIVGFNAFCSKHASGEGAMKIVNLLNDLYTRFDTLTDSRKNPFVYKVETVGDKYMTVSGLPEPCIHHARSICHLALDMMEIAGQVQVDGESVQITIGIHTGEVVTGVIGQRMPRYCLFGNTVNLTSRTETTGEKGKINVSEYTYRCLMSPENSDPQFHLEHRGPVSMKGKKEPMQVWFLSRKNT----GTEETNQDEN------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q02153-1", "uniprot_id": "GCYB1_HUMAN", "id": "Q02153-1", "name": "Guanylate cyclase soluble subunit beta-1", "aln": "MYGFVNHALELLVIRNYGPEVWEDIKKEAQLDEEGQFLVRIIYDDSKTYDLVAAASKVLNLNAGEILQMFGKMFFVFCQESGYDTILRVLGSNVREFLQNLDALHDHLATIYPGMRAPSFRCTDAEKGKGLILHYYSEREGLQDIVIGIIKTVAQQIHGTEIDMKVIQQRNE------------------------------------------------------------------------------------------------ECD----------------------HTQFLIEEK----ESKEEDFYEDLDRFEENGTQESRISPYTFCKAFPFHIIFDRDLVVTQCGNAIYRVLPQLQPGNCSLLSVFSLVRPHIDISFHGILSHINTVFVLRSKEGLLDVEKLECEDELTGTEISCLRLKGQMIYLPEADSILFLCSPSVMNLDDLTRRGLYLSDIPLHDATRDLVLLGEQFREEYKLTQELEILTDRLQLTLRALEDEKKKTDTLLYSVLPPSVANELRHKRPVPAKRYDNVTILFSGIVGFNAFCSKHASGEGAMKIVNLLNDLYTRFDTLTDSRKNPFVYKVETVGDKYMTVSGLPEPCIHHARSICHLALDMMEIAGQVQVDGESVQITIGIHTGEVVTGVIGQRMPRYCLFGNTVNLTSRTETTGEKGKINVSEYTYRCLMSPENSDPQFHLEHRGPVSMKGKKEPMQVWFLSRKNT----GTEETKQDDD------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "O54865-1", "uniprot_id": "GCYB1_MOUSE", "id": "O54865-1", "name": "Guanylate cyclase soluble subunit beta-1", "aln": "MYGFVNHALELLVIRNYGPEVWEDIKKEAQLDEEGQFLVRIIYDDSKTYDLVAAASKVLNLNAGEILQMFGKMFFVFCQESGYDTILRVLGSNVREFLQNLDALHDHLATIYPGMRAPSFRCTDAEKGKGLILHYYSEREGLQDIVIGIIKTVAQQIHGTEIDMKVIQQRNE------------------------------------------------------------------------------------------------ECD----------------------HTQFLIEEK----ESKEEDFYEDLDRFEENGTQESRISPYTFCKAFPFHIIFDRNLVVTQCGNAIYRVLPQLQPGNCSLLSVFSLVRPHIDISFHGILSHINTVFVLRSKEGLLDVEKLECEDELTGAEISCLRLKGQMIYLPEADSILFLCSPSVMNLDDLTRRGLYLSDIPLHDATRDLVLLGEQFREEYKLTQELEILTDRLQLTLRALEDEKKKTDTLLYSVLPPSVANELRHKRPVPAKRYDNVTILFSGIVGFNAFCSKHASGEGAMKIVNLLNDLYTRFDTLTDSRKNPFVYKVETVGDKYMTVSGLPEPCIHHARSICHLALDMMEIAGQVQVDGESVQITIGIHTGEVVTGVIGQRMPRYCLFGNTVNLTSRTETTGEKGKINVSEYTYRCLMSPENSDPLFHLEHRGPVSMKGKKEPMQVWFLSRKNT----GTEETNEEDEN-----------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9VA09-1", "uniprot_id": "Q9VA09_DROME", "id": "Q9VA09-1", "name": "Guanylate cyclase soluble subunit beta-1", "aln": "MYGFVNYALELLVLKHFGEEIWEKIKKKAMVSMEGQFLVRQIYDDEITYNLIGAAVEILNIPADDILELFGKTFFEFCQDSGYDKILQVLGATPRDFLQNLDALHDHLGTLYPGMRAPSFRCT--EKDGELLLHYYSERPGLEHIVIGIVKAVASKLHGVEVEIDIVKRKGEPIDEAEKERAIARENQQLLEDAVATTTTGSATVVLAPSSDAERNNNHNGSNGSNNNGMANNGNTVNVNNNNDGQQIASETDPSIALSTCPIAQDSFDCDGDKEQKCLRLLKNKSDDIERYDHVQFLIREINVAAKSQVDAKKDEVPDDMEFLCEAPLISPATFCKVFPFHLMFDRQMKIVQAGKAVSRVIPRVAEENCSLIEVVEAIRPHLQLNFENILSHINTIYVLQTRQGAMSSR----------HEQRFLRLKGQMMYIPETDRILFQCYPSVMNLDDLTKKGLYISDVPLHDAARDLVLLSEKFEAEYKLTKNLEMLTDKLQQTFRDLESEKQKTDRLLYSVLPKSVANELRHQRPVPPKRYDSVTLMFSGIVGFGQYCAANTDPDGAMKIVKMLNELYTVFDALTDSKRNLNVYKVETVGDKYMAVSGLPDHCEDHAKCMARVALDMMDMAKNVKMGSNPVQITIGIHSGEVVTGVIGNRVPRYCLFGNTVNLTSRTETTGVPGRINVSEETYRLLCMAINQDDSFHLEYRGPVIMKGKPTPMDCWFLTRATSSILGGTSSTGGSGGGGNGSLDSPLLQPATPTAGAATPIPVVAQRAAGHASVSRTSSAGGGGGGAVVGT", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "******:******::::* *:**.***:* :. ******* ****. **:*:.** ::**: *.:**::*** ** ***:****.**:***:. *:************.*:************ **. *:******* **:.*****:*:**.::**.*:::.:::::.* :** *.****.* :*: : ::: * : . *** ****.****::***:: :.*.*:*: **:*:: :***:.*.. :***:::.*..*******::**::::* :. . * *******:*:**:* *** * **********::***:**:*****:******.*:*. *****::**:***:** *:* **.**:*** ******* ********:****.****.**::*******. :*: ::. :******::**:*** **:****::* ************:*****: * .**:.:.::*****::* :*::..:.********:*********:*:******************** *:***** *** * . *.* ****:**** **** **: ***:* .: **..* . ", "identical_positions": 370, "similar_positions": 162, "identity": "46.31%" }, { "cls_id": "homologset.agr.MGI:1860606", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I6AV30-1", "uniprot_id": "A0A8I6AV30_RAT", "id": "A0A8I6AV30-1", "name": "", "aln": "NVYTFLHSFVQGSETTLQSTYCDTSAQPTCDYGYGTWNSGTNRGYENYGYGYGYGQDNTTNYGYGMATSHSWEMANSDTNANPSASGSASADSVLSRINQRLDMMPHLETDMIQGGVYGSGGGERYDSYEACDSRAILSERDLYRSSYDYGELDPEMEMAYEGQYDAYRDQFRMRGGDTFGPRAQGWARDARSGRPMASGYGRMWEDPMGARGQCMPGASRLPSLFSQNIIPEYGMFQGMRGGGAFSGGSRFGFGFGNGMKQMRRTWKTWTTADFRTKKKKRKQGGSPDEPDCKATRTDCSDNSDSDN-----GELGE---------------GEDEEGKEDGREEGKEDLEKGALTAQDESSQAKRKLQASKKSQDKQKKRQRDRMVERIQFVCSLCKYRTFYEDEMGSHLDSKFHKEHFKYVGTKLPKQTADFLQDYVTNKTKKTEELRKTVEDLDGLIQQIYRDQDLTQEIAMEHFVKKVEAAHCAACDLFIPMQFGIIQKHLKTMDHNRNRRLMMEQSKKSSLMVARSILNNKLISKKLERYLKGENPFTDNPEEEKEQDEVEAGALEEGAPSEATGLTEG---VSVQPPVPLEPTPGTATPPPPPPPEEE--NPVPLLGGALQCQIRGIPGLDVEDDEEGGGGP-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9R0L7-1", "uniprot_id": "AKP8L_MOUSE", "id": "Q9R0L7-1", "name": "A-kinase anchor protein 8-like", "aln": "---MSYTGFVQGSETTLQSTYCDTSAQPTCDYGYGTWNSGTNRGYENYGYGYGYGQDNTTNYGYGMATSHSWEMASSDTNANPSASGSASADSVLSRINQRLDMMPHLETDMIQGGVYGSGGGERYDSYEACDSRAILSERDLYRSSYDYGELDPEMEMAYEGQYDAYRDQFRMRGGDTFGPRAQGWARDARSGRPMASGYGRMWEDPMGARGQCMPGASRLPSLFSQNIIPEYGMFQGMRGGGAFSGGSRFGFGFGNGMKQMRRTWKTWTTADFRTKKKKRKQGGSPDEPDSKATRTDCSDNSDSDNDEGTEGEAAEGTESAEAMEKGSRVDGEDEEGKEDGREEGKEDPEKGALTAQDESSQAKRKLQASKKSQDKQKKRQRDRMVERIQFVCSLCKYRTFYEDEMGSHLDSKFHKEHFKYVGTKLPKQTADFLQEYVTNKTKKTEELRKTVEDLDGLIQQIYRDQDLTQEIAMEHFVKKVEAAHCAACDLFIPMQFGIIQKHLKTMDHNRNRRLMMEQSKKSSLMVARSILNNKLISKKLERYLKGENPFTDNPEEEKEQDEVEAGALDEGAPSEATELTEG---VPAQPPVPLEPAPGTTTPPPPPPPEEEE-SPVPLLGGALQCQIRGIPGLDMEDDEEGGGGP-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9ULX6-1", "uniprot_id": "AKP8L_HUMAN", "id": "Q9ULX6-1", "name": "A-kinase anchor protein 8-like", "aln": "---MSYTGFVQGSETTLQSTYSDTSAQPTCDYGYGTWNSGTNRGYEGYGYGYGYGQDNTTNYGYGMATSHSWEMPSSDTNANTSASGSASADSVLSRINQRLDMVPHLETDMMQGGVYGSGG-ERYDSYESCDSRAVLSERDLYRSGYDYSELDPEMEMAYEGQYDAYRDQFRMRGNDTFGPRAQGWARDARSGRPMASGYGRMWEDPMGARGQCMSGASRLPSLFSQNIIPEYGMFQGMRGGGAFPGGSRFGFGFGNGMKQMRRTWKTWTTADFRTKKKKRKQGGSPDEPDSKATRTDCSDNSDSDNDEGTEGEATEGLEGTEAVEKGSRVDGEDEEGKEDGREEGKEDPEKGALTTQDENGQTKRKLQAGKKSQDKQKKRQRDRMVERIQFVCSLCKYRTFYEDEMASHLDSKFHKEHFKYVGTKLPKQTADFLQEYVTNKTKKTEELRKTVEDLDGLIQQIYRDQDLTQEIAMEHFVKKVEAAHCAACDLFIPMQFGIIQKHLKTMDHNRNRRLMMEQSKKSSLMVARSILNNKLISKKLERYLKGENPFTDSPEEEKEQEEAEGGALDEGAQGEAAGISEGAEGVPAQPPVPPEPAPGAVSPPPPPPPEEEEEGAVPLLGGALQRQIRGIPGLDVEDDEEGGGGAP", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .*************.************************.***************************..******.*********************:*******:********* *******:*****:*********.***.*************************.***************************************.*****************************.*********************************************.*************** ** * ***************** ******:***..*:******.************************************.****************************:*********************************************************************************************************************.*******:*.*.***:*** .**: ::** *..***** **:**:.:********** ..********* *********:*********. ", "identical_positions": 567, "similar_positions": 42, "identity": "87.23%" }, { "cls_id": "homologset.agr.MGI:1860611", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O70400-1", "uniprot_id": "PDLI1_MOUSE", "id": "O70400-1", "name": "PDZ and LIM domain protein 1", "aln": "-------------------------------------MTTQQIVLQGPGPWGFRLVGGKDFEQPLAISRVTPGSKAAIANLCIGDLITAIDGEDTSSMTHLEAQNKIKGCADNMTLTVSRSEQ-----------------KIWSPLVTEEGKRHPYKMNLASEPQEVLHIGSAHNRSAMPFTASPAPST--RVITNQYNS----------PTGLYSSENISNFNNAVESKTSASGEEANSRPVVQPHPSGSLIIDKDSEVYKMLQEKQ-ELNEPPKQSTSFLVLQEILESDGKGDPNKPSGFRSVKAPVTKVAAS------------------VGNAQKLPICDKCGTGIVGVFVKLRDHHRHPECYVCTDCG--------------------------------INLKQKGHFFVEDQIYCEKHARERVTPPEGYDVVTVFRE--------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P52944-1", "uniprot_id": "PDLI1_RAT", "id": "P52944-1", "name": "PDZ and LIM domain protein 1", "aln": "-------------------------------------MTTQQIVLQGPGPWGFRLVGGKDFEQPLAISRVTPGSKAAIANLCIGDLITAIDGEDTSSMTHLEAQNKIKGCVDNMTLTVSRSEQ-----------------KIWSPLVTEEGKRHPYKMNLASEPQEVLHIGSAHNRSAMPFTASPAPGT--RVITNQYNS----------PTGLYSSENISNFNNAVESKTSASGEEANSRPSAQPHPSGGLIIDKESEVYKMLQEKQ-ELNEPPKQSTSFLVLQEILESDGKGDPNKPSGFRSVKAPVTKVAAS------------------VGNAQKLPICDKCGTGIVGVFVKLRDHHRHPECYVCTDCG--------------------------------INLKQKGHFFVGDQIYCEKHARERVTPPEGYDVVTVFPK--------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O00151-1", "uniprot_id": "PDLI1_HUMAN", "id": "O00151-1", "name": "PDZ and LIM domain protein 1", "aln": "-------------------------------------MTTQQIDLQGPGPWGFRLVGGKDFEQPLAISRVTPGSKAALANLCIGDVITAIDGENTSNMTHLEAQNRIKGCTDNLTLTVARSEH-----------------KVWSPLVTEEGKRHPYKMNLASEPQEVLHIGSAHNRSAMPFTASPASSTTARVITNQYNN----------PAGLYSSENISNFNNALESKTAASGVEANSRPLDHAQPPSSLVIDKESEVYKMLQEKQ-ELNEPPKQSTSFLVLQEILESEEKGDPNKPSGFRSVKAPVTKVAAS------------------IGNAQKLPMCDKCGTGIVGVFVKLRDRHRHPECYVCTDCG--------------------------------TNLKQKGHFFVEDQIYCEKHARERVTPPEGYEVVTVFPK--------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "B7YZE5-1", "uniprot_id": "B7YZE5_DROME", "id": "B7YZE5-1", "name": "PDZ domain-containing protein", "aln": "MPEQLGLLWSVPESKSKAPIIKVSCGIGDTDGYPAFDVDSDAYATKDDSRWGFLITGGAEFHMPLTVFQVTPNGLADKAGIRLGDIILEINEEDASQLTLSQAHEKINSTPKKIHFLLRNMEEDDPMGQFEAGEEKSIVMRVPKPLPPPSGRIRASSIEMRLLEMQRKLSAIAEIPKILCSTLATVSQNFGRMSESEVDEDDVGEEEAYVQRKFSYDEDALDFELRNGEQAGDTDSDEEDLVLVREEDAEDVDVPKGAKQSKLLKDVTPESDYASEANYPANEASDDTESDDEDEPGSTVYFMKLPAAAAEDTYSSTEDEDDSDFLNTTYTWNLRNVPKLRINDAEAEGELTLGHQAREVPQQEQPQEKQPCLEPEPPKVRPATPTPKAPPQESAEGQTQKLLFRLDKLERSWPWADREKIIYKQSTCHLVPRKPLGLVGQRMQLLLKDKKE", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : :: :. . *** :.** :*. **:: :***.. * *.: :**:* *: *::*.:* :*:::*:. .:: : : . *. :: .** . .*: :. .::: : . *. . : * :... . *: .: :. : .*: :*: .::. :. : :. : . . .: : * :: *:*:: * : ..: . . .: **: :.:*... * .: *..:: : * : *. ** : * . * : : : *: :: : * : ::. :. : *:: ::.* : :* : ", "identical_positions": 51, "similar_positions": 137, "identity": "11.28%" }, { "cls_id": "homologset.agr.MGI:1860763", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "B0BNA7-1", "uniprot_id": "EIF3I_RAT", "id": "B0BNA7-1", "name": "Eukaryotic translation initiation factor 3 subunit I", "aln": "MKPILLQGHERSITQIKYNREGDLLFTVAKDPIVNVWYSVNGERLGTYMGHTGAVWCVDADWDTKHVLTGSADNSCRLWDCETGKQLALLKTNSAVRTCGFDFGGNIIMFSTDKQMGYQCFVSFFDLRDP-SQIDS----NEPYMKIPCND--SKITSAVWGPLGECIIAGHESGELNQYSAKSGE-VLVNVKEHSRQINDIQLSRDMTMFVTASKDNTAKLFDSTSLEHQKTFRTERPVNSAALSPNYDHVVLGGGQEAMDVTTTSTRIGKFEARFFHLAFEEEFGRVKGHFGPINSVAFHPDGKSYSSGGEDGYVRIHYFDPQYFEFEFEA--------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q13347-1", "uniprot_id": "EIF3I_HUMAN", "id": "Q13347-1", "name": "Eukaryotic translation initiation factor 3 subunit I", "aln": "MKPILLQGHERSITQIKYNREGDLLFTVAKDPIVNVWYSVNGERLGTYMGHTGAVWCVDADWDTKHVLTGSADNSCRLWDCETGKQLALLKTNSAVRTCGFDFGGNIIMFSTDKQMGYQCFVSFFDLRDP-SQIDN----NEPYMKIPCND--SKITSAVWGPLGECIIAGHESGELNQYSAKSGE-VLVNVKEHSRQINDIQLSRDMTMFVTASKDNTAKLFDSTTLEHQKTFRTERPVNSAALSPNYDHVVLGGGQEAMDVTTTSTRIGKFEARFFHLAFEEEFGRVKGHFGPINSVAFHPDGKSYSSGGEDGYVRIHYFDPQYFEFEFEA--------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9QZD9-1", "uniprot_id": "EIF3I_MOUSE", "id": "Q9QZD9-1", "name": "Eukaryotic translation initiation factor 3 subunit I", "aln": "MKPILLQGHERSITQIKYNREGDLLFTVAKDPIVNVWYSVNGERLGTYMGHTGAVWCVDADWDTKHVLTGSADNSCRLWDCETGKQLALLKTNSAVRTCGFDFGGNIIMFSTDKQMGYQCFVSFFDLRDP-SQIDS----NEPYMKIPCND--SKITSAVWGPLGECVIAGHESGELNQYSAKSGE-VLVNVKEHSRQINDIQLSRDMTMFVTASKDNTAKLFDSTTLEHQKTFRTERPVNSAALSPNYDHVVLGGGQEAMDVTTTSTRIGKFEARFFHLAFEEEFGRVKGHFGPINSVAFHPDGKSYSSGGEDGYVRIHYFDPQYFEFEFEA--------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q7ZV55-1", "uniprot_id": "EIF3I_DANRE", "id": "Q7ZV55-1", "name": "Eukaryotic translation initiation factor 3 subunit I", "aln": "MKPILLQGHERSITQIKYNREGDLLFSVAKDPIANVWYSVNGERLGTYNGHTGAVWCVDVDWDTKNVLTGSADNSCRLWDCETGKQLALLETSSAVRTCGFDFSGNIIMFSTDKQMGYQCFLNYYDLRDP-QQIED----NQPYISVPCSE--SKITSAVWGPLGEFVIAGHENGEINQFSAKSGE-VLKKAKEHTKQINDIQSSVDLTMIISASKDCTAKMFDSSTLEHVKTFKTERPVNSAAISPIMDHVVMGGGQEAMEVTTTSTRIGKFEARFFHAAYEEEFGRVKGHFGPINCVAFHPDGKSYSSGGEDGYVRIHYFDPHYFDFELEA--------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "O02195-1", "uniprot_id": "EIF3I_DROME", "id": "O02195-1", "name": "Eukaryotic translation initiation factor 3 subunit I", "aln": "MRPLMLQGHERSITQIKYNREGDLLFSCSKDQKPNVWYSLNGERLGTYDGHQGAVWCLDVDWESRKLITGAGDMTAKIWDVEYGTVIASIPTKSSVRTSNFSFSGNQAAYSTDKAMGQSCELFLIDVRNADSSLSE----QEPTLRIPMTE--SKITSMLWGPLDETIITGHDNGNIAIWDIRKGQKVVDSGTDHSAGINDMQLSKDGTMFVTASKDTTAKLFDSESLMCLKTYKTERPVNSAAISPIMDHVVLGGGQDAMEVTTTSTKAGKFDSRFFHLIYEEEFARLKGHFGPINSLAFHPDGKSYASGGEDGFVRVQTFDSTYFENIFE---------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P40217-1", "uniprot_id": "EIF3I_YEAST", "id": "P40217-1", "name": "Eukaryotic translation initiation factor 3 subunit I", "aln": "MKAIKLTGHERPLTQVKYNKEGDLLFSCSKDSSASVWYSLNGERLGTLDGHTGTIWSIDVDCFTKYCVTGSADYSIKLWDVSNGQCVATWKSPVPVKRVEFSPCGNYFLAILDNVMKNPGSINIYEIERDSATHELTKVSEEPIHKIITHEGLDAATVAGWSTKGKYIIAGHKDGKISKYDVSNNYEYVDSIDLHEKSISDMQFSPDLTYFITSSRDTNSFLVDVSTLQVLKKYETDCPLNTAVITPLKEFIILGGGQEAKDVTTTSANEGKFEARFYHKIFEEEIGRVQGHFGPLNTVAISPQGTSYASGGEDGFIRLHHFEKSYFDFKYDVEKAAEAKEHMQEAN", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*:.: * ****.:**:***:******: :** .****:******* ** *::*.:*.* :: :**:.* : ::** . * :* : .*: *. ** *: * : ::. . ::* : : . * *.. .: :*:**..*:: :. .. : . * *.*:* * * * ::::*:* .: :.* :* *.:.*: *:*:*.::* :.:::****:* :*****:. ***::**:* :***:.*::*****:* :*: *:*.**:******::*:: *: **: : ", "identical_positions": 114, "similar_positions": 108, "identity": "32.85%" }, { "cls_id": "homologset.agr.MGI:1860764", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q62865-1", "uniprot_id": "PDE3A_RAT", "id": "Q62865-1", "name": "cGMP-inhibited 3',5'-cyclic phosphodiesterase 3A", "aln": "MAVRGEAAQDWAKPGLRGPSPAPVARGDHRCRGGSPSSPRGSGC--CWRALALQPLRRSPQLSSALCAGSLSVLLALLVRLVGGEVGGELESSQEAAAEEEEEE--GARGGVFPGPRGGAPGGGAQLSPWLQPAALLFSLLCAFFWMGLCLLRAGVRLPLAVALLAACCAGEALVQLSLGVGDGRLLSLPAAGVLLSCLGGATWLVLRLRLGVLMVALTSALRTVALVSLERFKVAWRPYLAYLAAVLGLLLARYAEQLLPQCSGPAPPRERFGSQSSARTKEEIPGWKRRRRSSSVVAGEMSGCG---GKSHRRTSLPCIPREQLMGHSEWDHKRGSRGSQS--------GTSVTVDIAVMGEAHGLITDLLADPSLPPNVCTSLRAVSNLLSTQLTFQAIHK-PRVNPTVTFSENYTCSDSEEGLEK-DKLAIPKRLRRSLPPGLLRRVSSTWTTTTSATGLPTLEPAPVRRDRSASIKP-HEAPSPSAVNPDSWNAPVLMTLTKSRSFTSSYAVS--AANHVKAKKQNRPGGLDKISPVPSPSSSP-PQGSPTSSPVSGIASVQFPESPEVTTKRGPGSHRALTYTQSAPDLSPQIPPSP-VICSSCGRPYSQGNPADGPSERSGPAMQKPNRTDDTSQVTSDYETNNNSDSSDILQNDEEAECQREPLRKASACGTYTPQTMIFLD-KPILAPEPLVMDNLDSIMDQLNTWNFPIFDLVENIGRKCGRILSQVSYRLFEDMGLFEAFKIPVREFMNYFHALEIGYRDIPYHNRIHATDVLHAVWYLTTQPIPGLPSVIGDHGSASDSDSDSGFTHGHMGYVFSKAYHVPDDKYGCLSGNIPALELMALYVAAAMHDYDHPGRTNAFLVATSAPQAVLYNDRSVLENHHAAAAWNLFMSRPEYNFLVNLDHVEFKHFRFLVIEAILATDLKKHFDFVAKFNAKVNDD--VGIDWTNENDRLLVCQMCIKLADINGPAKCKDLHLRWTEGIASEFYEQGDEEASLGLPISPFMDRSAPQLANLQESFISHIVGPLCHSYDSAGLMPGKWVDDSDDSGD--TDDPEEEEEEAETPHEEETCENSEAPRKKS-FKRRRIYCQITQHLLQNHMMWKKVIEEEQCLSGTENQAPDQAPLQHSSEQIQAIKEEEEE----------KGKPRAEETLAPQPDL--------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9Z0X4-1", "uniprot_id": "PDE3A_MOUSE", "id": "Q9Z0X4-1", "name": "cGMP-inhibited 3',5'-cyclic phosphodiesterase 3A", "aln": "MAVRGEAAQDLAKPGLGGASPARVARGNHRHRGESSPSPRGSGC--CWRALALQPLRRSPQLSSALCAGSLSVLLALLVRLVGGEVGGELEKSQEAAAEEEEEE--GARGGVFPGPRGGAPGGGAQLSPWLQPAALLFSLLCAFFWMGLCLLRAGVRLPLAVALLAACCAGEALVQLSLGVGDGRLLSLPAAGVLLSCLGGATWLVLRLRLGVLMVAWTSVLRTVALVSLERFKVAWRPYLAYLAAVLGLLLARYAEQILPQCSGPAPPRERFGSQLSARTKEEIPGWKRRRRSSSVVAGEMSGCS---GKSHRRTSLPCIPREQLMGHSEWDHKRGPRGSQS--------GTSITVDIAVMGEAHGLITDLLADPSLPPNVCTSLRAVSNLLSTQLTFQAIHK-PRVNPTVTFSENYTCSDSEEGLEK-DKQAISKRLRRSLPPGLLRRVSSTWTTTTSATGLPTLEPAPVRRDRSASIKP-HEAPSPSAVNPDSWNAPGLTTLTKSRSFTSSYAVS--AANHVKAKKQNRPGGLAKISPVPSPSSSP-PQGSPASSPVSNSASQQFPESPEVTIKRGPGSHRALTYTQSAPDLSPQIPPPS-VICSSCGRPYSQGNPADGPSERSGPAMLKPNRTDDTSQVTSDYETNNNSDSSDILQNEEEAECQREPQRKASACGTYTSQTMIFLD-KPILAPEPLVMDNLDSIMDQLNTWNFPIFDLMENIGRKCGRILSQVSYRLFEDMGLFEAFKIPVREFMNYFHALEIGYRDIPYHNRIHATDVLHAVWYLTTQPIPGLPSVIGDHGSASDSDSDSGFTHGHMGYVFSKMYHVPDDKYGCLSGNIPALELMALYVAAAMHDYDHPGRTNAFLVATSAPQAVLYNDRSVLENHHAAAAWNLFMSRPEYNFLVNLDHVEFKHFRFLVIEAILATDLKKHFDFVAKFNAKVNDD--VGIDWTNENDRLLVCQMCIKLADINGPAKCKELHLRWTEGIASEFYEQGDEEASLGLPISPFMDRSAPQLANLQESFISHIVGPLCHSYDSAGLMPGKWVDDSDDSGD--TDDPEEEEEEAETPHEDEACESSIAPRKKS-FKRRRIYCQITQHLLQNHMMWKKVIEEEQCLSGTENQSLDQVPLQHPSEQIQAIKEEEEE----------KGKPRAEETLAPQPDL--------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q14432-1", "uniprot_id": "PDE3A_HUMAN", "id": "Q14432-1", "name": "cGMP-inhibited 3',5'-cyclic phosphodiesterase 3A", "aln": "MAVPGDAARVRDKPVHSGVSQAPTAGRDCHHR-ADPASPRDSGCRGCWGDLVLQPLRSSRKLSSALCAGSLSFLLALLVRLVRGEVGCDLEQCKEAAAAEEEEAAPGAEGGVFPGPRGGAPGGGARLSPWLQPSALLFSLLCAFFWMGLYLLRAGVRLPLAVALLAACCGGEALVQIGLGVGEDHLLSLPAAGVVLSCLAAATWLVLRLRLGVLMIALTSAVRTVSLISLERFKVAWRPYLAYLAGVLGILLARYVEQILPQSAEAAP-REHLGSQLIAGTKEDIPVFKRRRRSSSVVSAEMSGCS---SKSHRRTSLPCIPREQLMGHSEWDHKRGPRGSQSS-------GTSITVDIAVMGEAHGLITDLLADPSLPPNVCTSLRAVSNLLSTQLTFQAIHK-PRVNPVTSLSENYTCSDSEESSEK-DKLAIPKRLRRSLPPGLLRRVSSTWTTTTSATGLPTLEPAPVRRDRSTSIKL-QEAPSS---SPDSWNNPVMMTLTKSRSFTSSYAIS--AANHVKAKKQSRPGALAKISPLSSPCSSP-LQGTPASSLVSKISAVQFPESADTTAKQSLGSHRALTYTQSAPDLSPQILTPP-VICSSCGRPYSQGNPADEPLERSGVATRTPSRTDDTAQVTSDYETNNNSDSSDIVQNEDETECLREPLRKASACSTYAPETMMFLD-KPILAPEPLVMDNLDSIMEQLNTWNFPIFDLVENIGRKCGRILSQVSYRLFEDMGLFEAFKIPIREFMNYFHALEIGYRDIPYHNRIHATDVLHAVWYLTTQPIPGLSTVINDHGSTSDSDSDSGFTHGHMGYVFSKTYNVTDDKYGCLSGNIPALELMALYVAAAMHDYDHPGRTNAFLVATSAPQAVLYNDRSVLENHHAAAAWNLFMSRPEYNFLINLDHVEFKHFRFLVIEAILATDLKKHFDFVAKFNGKVNDD--VGIDWTNENDRLLVCQMCIKLADINGPAKCKELHLQWTDGIVNEFYEQGDEEASLGLPISPFMDRSAPQLANLQESFISHIVGPLCNSYDSAGLMPGKWVEDSDESGD--TDDPEEEEEEAPAPNEEETCENNESPKKKT-FKRRKIYCQITQHLLQNHKMWKKVIEEEQRLAGIENQSLDQTPQSHSSEQIQAIKEEEEE----------KGKPRGEEIPTQKPDQ--------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M3B8Q1-1", "uniprot_id": "A0A8M3B8Q1_DANRE", "id": "A0A8M3B8Q1-1", "name": "Phosphodiesterase", "aln": "------MALESVRNGYVRTCVTPVEQD-------------------CWHS----CLRSRRSLSSAVCVASLSVLLALLW---------DAERTHAHSG----------------------SHLVTLVELVWQLLSPVLTLVCAFFWVGVYLLRCGVLIRTAVFLLTVCHLGEAAAQSLLDAQQLYSFTATAL-VLLACLASGALMVVRLGQGISVLLFISIIRTVSLLSLQKVRASWRPYLAYLLGLLGVLLARYADRLLPEQ----------GASHREGSRGDIPVFKRRRRSSSVVSSDMAQHGQSRSKSHRRTSLPCLQREQMLPQQEWDNKRGARGSQQPSGLMQSSGTSVTVDIAVMGEAHGLISDLLADQSLAPNICSTLRAVSNLLNTQLTFQPLHHRPRLGPLLAFSDGHTCSDSEEAPEKGERLAIPKRLRRSLHPGLLRRISSTWTTTTSATGLPTLEPGPVRRDRSASIKAPHDGPSSSLVNSDSWNNSNMLSISKSRSMSASYAASSNTTNHIYSKSR-RGCSSSTISPLASPCHSPPVQSSPLTSPTNKTPSVELPD-PELPPPRSP--HKALTHSQSAPSSSAALWPPPTPLCSSCGRPYSKQRHSDGSTEPAERTQQSDEPAMMSSDYDSTYETN-HSDSSDFAQTDEDREARR----------TLTLATLIPAEEKPILAPEPLLMEGLEPLLCQINNWNFPIFSLVEKTNGRCGCILSQMSYRLFVDTGLFETFKIPVREFMNYFHALENGYRDIPYHNRIHATDVLHAVWYLTTQPVPGLPTLR----TLGSSDSDSGLAHGRMKYLMSRTNAVEEEGYGCLSGLIPALELMALYVAAAMHDYDHPGRTNAFLVATSAPQAVLYNDRSVLENHHAASAWNLFMSRPEYNFLASLDHMEFKRFRFLVIEAILATDLKKHFDFLAEFNAKVGDDGCSGIDWTNENDRLLVCQMCIKLADINGPLKCKDLHLQWTEGIVNEFYEQGDEESSLGLPISPFMDRSAPQLAKLQESFITHIVGPLCSSYDSAALMPGRWVHPLPKDGDEVEDESEEEDEDTAEEEEEDASTSSELSQKPAPKKRRKVFCQISHHLLENHEMWKKVIAEE---SQSQTEGEESTCLSTTPEPILAIDEEEEEPGSKEEPTDDQGEGSTEEEEGPVPEDTHETQEPDGETVEEADEKNTETVEDIEGKQDEDQKDPE", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * : . : . ** ** .****:*..***.***** : * : :. . : :. * : :::*:*****:*: ***.** : ** **:.* *** .* *.. : :: .* *:*:**...: :*:** *: :: * :***:*:**::.:.:******** .:**:*****.:::**: *:. :: :** :**********:.:*: . .**********: ***:: :.***:***.****. ***:**************:***** **.**:*::********.******.:*: **:.* ::*:.:*******. ** :: **.******* ******:******************.*******:*** ::.**. ..**** . : :::****:::*** * ::**: :*.: * . .***:.**. ** *.:* :* .. .: ::*: .: . :. *:***::****. *. : ... :*********: . :* . * : : . . : ::: * **** :*****: *.::: *. * * : *:: : *********:*:.*:.:: *:*.******.*:*: . :** ****:***** * ****:****:*********** ***************************:***.:: : ..******::**:* *::*: * :: ****** ***************************************************:************** .***:***:********************:*:**.**.** ************************** ***:***:**:**..*********:******************:******:******* *****.****:**. ..** *:.***:*:: .*:::. .. .:* : ***:::***::***:** ****** ** : :.:. :.. . ..* * **.***** :*: ** *: ", "identical_positions": 600, "similar_positions": 269, "identity": "49.3%" }, { "cls_id": "homologset.agr.MGI:1860765", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A0G2K6F4-1", "uniprot_id": "A0A0G2K6F4_RAT", "id": "A0A0G2K6F4-1", "name": "Exostosin-like 3", "aln": "-MTGYTMLRNG--------GVGNGGQTCMLR---------------WSNRIRLTWLSFTLFIILVFFPLIAHYYLTTLDEADEAGKRIFGPRAGN--ELCEVKH------VLDLCRIRESVSEELLQLEAKRQELNSEIAKLNLKIEACKKSIENAKQDLLQLKNVISQTEHSYKELMAQNQPKLSLPIRLLPEKDDAGLPPPK--VTRGCRLHNCFDYSRCPLTSGFPVFVYDSDQFAF---GSYLDPLVKQAFQATVRANVYVTENAAIACLYVVLVGE-IQEPAVLQ-----------------------PADLEKQLHSLPHWRTDGHNHVIINLSRK---SDTQNLLYNVSTGRAMVAQSTFYAAQYRAGFDLVVSPLVHAMSEPNFMEIPPQVPVKRKYLFTFQGEKIESLRSSLQEARSFEEEMEGDPPADYDDRIIATLKAVQDSKLDQVLVEFTCKNQPKPSLPTEWALCGEREDRLELLKLSTFALIITPGDPSLLISSGCATRLFEALEVGAVPVVLG-EQVQLPYHDMLQWNEAALVVPKPRVTEVHFLLRSLSDSDLLAMRRQGRFLWETYFSTADSIFNTVLAMIRTRIQIPAAPIREEVAAEIPHRSGKAAGTDPNMADNGDLDLGPVETEPPYASPKYLRNFTLTVTDCYRSWNSAPGPFHLFPHTPFDPVLPSEAKFLGSGTGFRPIGGGAGGSGKEFQAALGGNVQREQFTVVMLTYEREEVLMNSLERLNGLPYLNK-------------------------VVRTEKNSLNNRFLPWNEIETEAILSIDDDAHLRHDEIMFGFRVWREARDRIVGFPGRYHAWDI--PHQSWLYNSNYSCELSMVLTGAAFFHKYYAYLYSYVMPQAIRDMVDEYINCEDIAMNFLVSHITRKPPIKVTSRWTFRCPGCPQALSHDDSHFHERHKCINFFVKVYGYMPLLYTQFRVDSVLFKTRLPHDKTKCFKFI", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9WVL6-1", "uniprot_id": "EXTL3_MOUSE", "id": "Q9WVL6-1", "name": "Exostosin-like 3", "aln": "-MTGYTMLRNG--------GVGNGGQTCMLR---------------WSNRIRLTWLSFTLFIILVFFPLIAHYYLTTLDEADEAGKRIFGPRAGS--ELCEVKH------VLDLCRIRESVSEELLQLEAKRQELNSEIAKLNLKIEACKKSIENAKQDLLQLKNVISQTEHSYKELMAQNQPKLSLPIRLLPEKDDAGLPPPK--VTRGCRLHNCFDYSRCPLTSGFPVYVYDSDQFAF---GSYLDPLVKQAFQATVRANVYVTENAAIACLYVVLVGE-MQEPTVLR-----------------------PADLEKQLFSLPHWRTDGHNHVIINLSRK---SDTQNLLYNVSTGR-HVAQSTFYAAQYRAGFDLVVSPLVHAMSEPNFMEIPPQVPVKRKYLFTFQGEKIESLRSSLQEARSFEEEMEGDPPADYDDRIIATLKAVQDSKLDQVLVEFTCKNQPKPSLPTEWALCGEREDRLELLKLSTFALIITPGDPHLLISSGCATRLFEALEVGAVPVVLG-EQVQLPYHDMLQWNEAALVVPKPRVTEVHFLLRSLSDSDLLAMRRQGRFLWETYFSTADSIFNTVLAMIRTRIQIPAAPIREEVAAEIPHRSGKAAGTDPNMADNGDLDLGPVETEPPYASPKYLRNFTLTVTDCYRGWNSAPGPFHLFPHTPFDPVLPSEAKFLGSGTGFRPIGGGAGGSGKEFQAALGGNVQREQFTVVMLTYEREEVLMNSLERLNGLPYLNKVVVVWNSPKLPSEDLLWPDIGVPIMVVRTEKNSLNNRFLPWNEIETEAILSIDDDAHLRHDEIMFGFRVWREARDRIVGFPGRYHAWDI--PHQSWLYNSNYSCELSMVLTGAAFFHKYYAYLYSYVMPQAIRDMVDEYINCEDIAMNFLVSHITRKPPIKVTSRWTFRCPGCPQALSHDDSHFHERHKCINFFVKVYGYMPLLYTQFRVDSVLFKTRLPHDKTKCFKFI", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O43909-1", "uniprot_id": "EXTL3_HUMAN", "id": "O43909-1", "name": "Exostosin-like 3", "aln": "-MTGYTMLRNG--------GAGNGGQTCMLR---------------WSNRIRLTWLSFTLFVILVFFPLIAHYYLTTLDEADEAGKRIFGPRVGN--ELCEVKH------VLDLCRIRESVSEELLQLEAKRQELNSEIAKLNLKIEACKKSIENAKQDLLQLKNVISQTEHSYKELMAQNQPKLSLPIRLLPEKDDAGLPPPK--ATRGCRLHNCFDYSRCPLTSGFPVYVYDSDQFVF---GSYLDPLVKQAFQATARANVYVTENADIACLYVILVGE-MQEPVVLR-----------------------PAELEKQLYSLPHWRTDGHNHVIINLSRK---SDTQNLLYNVSTGRAMVAQSTFYTVQYRPGFDLVVSPLVHAMSEPNFMEIPPQVPVKRKYLFTFQGEKIESLRSSLQEARSFEEEMEGDPPADYDDRIIATLKAVQDSKLDQVLVEFTCKNQPKPSLPTEWALCGEREDRLELLKLSTFALIITPGDPRLVISSGCATRLFEALEVGAVPVVLG-EQVQLPYQDMLQWNEAALVVPKPRVTEVHFLLRSLSDSDLLAMRRQGRFLWETYFSTADSIFNTVLAMIRTRIQIPAAPIREEAAAEIPHRSGKAAGTDPNMADNGDLDLGPVETEPPYASPRYLRNFTLTVTDFYRSWNCAPGPFHLFPHTPFDPVLPSEAKFLGSGTGFRPIGGGAGGSGKEFQAALGGNVPREQFTVVMLTYEREEVLMNSLERLNGLPYLNKVVVVWNSPKLPSEDLLWPDIGVPIMVVRTEKNSLNNRFLPWNEIETEAILSIDDDAHLRHDEIMFGFRVWREARDRIVGFPGRYHAWDI--PHQSWLYNSNYSCELSMVLTGAAFFHKYYAYLYSYVMPQAIRDMVDEYINCEDIAMNFLVSHITRKPPIKVTSRWTFRCPGCPQALSHDDSHFHERHKCINFFVKVYGYMPLLYTQFRVDSVLFKTRLPHDKTKCFKFI", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9XZ08-1", "uniprot_id": "EXT3_DROME", "id": "Q9XZ08-1", "name": "Exostosin-3", "aln": "MPPAYDLGHSGEAYQPLDTGSGGGNEACAPNSSSAQIRHSMGFRTSWMRQFRRYKLPMVLLMLLFLVSCLAYRILSVEQDAPPLDLHRSSPLLDAYEDFSAMRAGDLKMRIEEMVRIKSTVSVELRELESRRQKLQSDISQYNQKIEELKQELLREQTELERLKISVEQAQVAQREAVQRNTPDLALPRSLLPNTLPRKSNPITGGMAASCEMHNCFNHSRCSLTSGFPVYLYDPDEHSVQRKGYDIDGFLKTTLKQTLGYNAHIVKDPKHACIYLVLVGEALLEQDLLRNNRYAAQEAEHQQPSTPTLENDCPVDMEK-LYSLPYWGGDGRNHVLLNLARRDLTSHRTNPLYRQNTMRAIVVQSAFEREQFRPGYDLIVPPILGPPGGDVWQECAEMVPARRKYLLTYQG-ELRPKQSSLNPLDAFILEHLAD----------MAKGATQDQFVLQFQCVPATEQQEGDSLP-DWTLCGSDSSRRQLLKDSTFSLILPPLN-GRVSSTLMLARIYEALRSGAVPVILGADELRLPYAETVDWRRTALLLPKARITELHFLLRAVQDADLLLLRRQGRLIWERYLSSVQATVDTVIASLRDRLGIPPRPVPSVIAQSVFNSTFIPLKSDPPVGLDTEPEESLGPIEPPYPSPAFRRNYTILRMQAKEAWNDWLDPFYLYPQLPFDPALPSEAKFMGSHTGFRPIGKGLGGAGKEFGESLGGNYPREQFTIVMLTYEREQVLMDSLGRLYGLPYLHKVVVVWNSPKPPLDDLRWPDIGVPVAVLRAPRNSLNNRFLPFDVIETEAVLSVDDDAHLRHDEILFGFRVWREHRDRVVGFPGRYHAWDLGNPNGQWHYNSNYSCELSMVLTGAAFVHKYYLYLYTYHLPQAIRDKVDEYMNCEDIAMNFLVSHITRKPPVKVTSRWTFRCPGCPVSLSEDDTHFQERHKCINFFSRVFGYTPLLNTQYRADSILFKTRIPHDKQKCFKYI", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ..* : :.* * *.*.::* . * .::* *.:.*:::*.:.. :*: *:. ::* . : .* . ::. :: : :: **:.:** ** :**::**:*:*:*:: * *** *:.: . : :* :** :.*:: : :* : :* *.*:** ***:. * . : .*.:****::***.*******::**.*:. . * :* ::* ::: * *.::.::. **:*::**** : * :*: *.::** *.***:* **:***::**:*: *. * **. .* * *.**:* *:*.*:**:*.*:: . . : * . **.:****:*:** ::.. :***: :* * .* : *.**. : *. : ::* *** :*:***. ..* :*** ***:**:.* : : *: :*::***. *****:** ::::*** : ::*..:**::**.*:**:*****::.*:*** :*****::** *:*:.:: .:**:* :* *: **. *: . * .: : : . :** :. : : : . ****.** : **:*: : ..** .**:*:*: ****.*******:** ******* * **:**** :**** *****:********:***:** ** *****:* *:*: :*********:: *****:**:***********:******** ***:***********: *: .* ******************.**** ***:* :****** ****:*******************:************** :**.**:**:********* :*:** *** **:*.**:*****:**** ****:*", "identical_positions": 436, "similar_positions": 261, "identity": "44.22%" }, { "cls_id": "homologset.agr.MGI:1860775", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0ABK0LPE7-1", "uniprot_id": "A0ABK0LPE7_RAT", "id": "A0ABK0LPE7-1", "name": "Actin-related protein 8", "aln": "----------------------------------------------------------------------------------------------------------------------------MLPSCSSSPRAFSPFLRFEVPGLHHHQKQKKEKSNFNRVVPSVPESSTGDAGGGHLDCGQPGDAAPARWFSTAYCGVGVPEPRGCWWSVVAEMTQAEKGDAENGKEKGGEKEKEQ-RGVKRPIVPALVPESLQEQIQSN---FIVVVHPGSTTLRIGRATDTLPASIPHVIARRHKQQGQPLYKDNWLLR--EGLNKPESNEQRQNGLKMVDQAIWSKKMSNGTRRIPVSPEQ------TRSYNKQMRPAILDHCSGNKWTNTSHQPEYLVGEEALYVNPLDCYNIHWPIRRGQLNIHPGPGGSLTAVLADIEVIWSHAIQ-KYLEIPLKDLKYYRCILLIPDIYNKQHVKELVHMILMKMGFAGIVVHQESVCATFGSGLS-STCVVDVGDQKTSVCCVEDGVSHRNTRLCLAYGGSDVSRCFYWLMQRAGFPYRECQLAN-KMDCLLLQHLKETFCHLDQDISGLQDHEFQIRHPDSPALLYQFRLGDEKLQAPMALFYPATFGIVGQKMTTLQHRSQGDPED----PHDEHYLLATQSKQEQSAKATADRKSASKPIGFEGDLRGQSSDLPER--LHSQEVDLASSQGDCLMAGNESEEALTALMSRKTAISL------FEGKALGLDKAILHSVDCCSS--------DDTKKKMYSSILVVG----------GGLMFHKAQEFLQHRILNKMPPSFRRIIEN--------VDVITRPK--------------VSCFAI---------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8R2S9-1", "uniprot_id": "ARP8_MOUSE", "id": "Q8R2S9-1", "name": "Actin-related protein 8", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MTQAEKGDAENGKEKGGEKEKEQ-RGVKRPIVPALVPESLQEQIQSN---FIVVIHPGSTTLRLGRATDTLPVSVPHVIARRHKQQGQPLYKDNWLLR--EGLNKPESNEQRQNGLKMVDQAIWSKKMSNGTRRIPVSPEQ------TRSYNKQMRPAILDHCSGNKWTNTSQQPEYLVGEEALYVNPLDCYNIHWPIRRGQLNIHPGPGGSLTAVLADIEVIWSHAIQ-KYLEIPLKDLKYYRCILLIPDIYNKQHVKELVHMILMKMGFAGIVVHQESVCATFGSGLS-STCVVDVGDQKTSVCCVEDGVSHRNTRLCLAYGGSDVSRCFYWLMQRAGFPYRECQLTN-KMDCLLLQHLKETFCHLDQDISGLQDHEFQIRHPDSPALLYQFRLGDEKLQAPMALFYPATFGIVGQKMTTLQHRSQGDPED----PHDEHYLLATQSKQEQSAKATADRKSASKPIGFEGDLRGQSSDLPER--LHSQEVDLASSQGDCLMAGNESEEALTALMSRKTAISL------FEGKALGLDKAILHSVDCCSS--------DDTKKKMYSSILVVG----------GGLMFHKAQEFLQHRILNKMPPSFRRIIEN--------VDVITRPKDMDPRLIAWKGGAVLACLDTTQELWIYQREWQRFGVRMLRERAAFVW", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9H981-1", "uniprot_id": "ARP8_HUMAN", "id": "Q9H981-1", "name": "Actin-related protein 8", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MTQAEKGDTENGKEKGGEKEKEQ-RGVKRPIVPALVPESLQEQIQSN---FIIVIHPGSTTLRIGRATDTLPASIPHVIARRHKQQGQPLYKDSWLLR--EGLNKPESNEQRQNGLKMVDQAIWSKKMSNGTRRIPVSPEQ------ARSYNKQMRPAILDHCSGNKWTNTSHHPEYLVGEEALYVNPLDCYNIHWPIRRGQLNIHPGPGGSLTAVLADIEVIWSHAIQ-KYLEIPLKDLKYYRCILLIPDIYNKQHVKELVNMILMKMGFSGIVVHQESVCATYGSGLS-STCIVDVGDQKTSVCCVEDGVSHRNTRLCLAYGGSDVSRCFYWLMQRAGFPYRECQLTN-KMDCLLLQHLKETFCHLDQDISGLQDHEFQIRHPDSPALLYQFRLGDEKLQAPMALFYPATFGIVGQKMTTLQHRSQGDPED----PHDEHYLLATQSKQEQSAKATADRKSASKPIGFEGDLRGQSSDLPER--LHSQEVDLGSAQGDGLMAGNDSEEALTALMSRKTAISL------FEGKALGLDKAILHSIDCCSS--------DDTKKKMYSSILVVG----------GGLMFHKAQEFLQHRILNKMPPSFRRIIEN--------VDVITRPKDMDPRLIAWKGGAVLACLDTTQELWIYQREWQRFGVRMLRERAAFVW", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P59679-1", "uniprot_id": "ARP8_DANRE", "id": "P59679-1", "name": "Actin-related protein 8", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MTQTDR-DAENGRDREKDREKEQQRGVKRPIMPAAVPEPVQEQIQAN---FIVVIHPGSRTLRLGRATDTLPISVPHVIARRHKHPGQSRYEDKCLLR--EGLNSADSNEQRQNGLKMVDQVIWSKKMSNGVRRTPVSAEQ------ARLYNRQIRPAVLDPNSKVSWTNTSHHPEYVVGEEALYVNPTDCYSVHWPVCRGRLNLHSGSGGSLSAVMMDLEHIWTHALQ-KLLQIPLKDLKYYRCILLIPDIYNRQHVKEIVNMLLVKMGFSAVVVHQESVCATFGSGLS-SACVVDVGDQKTSVCCVEDGVSHRSSRLCLAYGGSDVTRCFFWLMQRAGFPYRDCQLGN-KLDCVLLQQLKESFCHLDQDISGLQDHEFRTRFPDSPVLLYQLRLGDEKLQAPMTLFYPAAFGIVGQRMTSLLHRSQGDAED----PHDEHFLLTTQSKQDQSSKASADRKSFPKPSSFEGES--SVCEVSDRS-SLGQDLDLGHSQAECLVGGAETEETPSALLSRKTAMSQ------FEGKALGIDKAILHSIDSCAS--------DETKRKMYSCILVVG----------GGLLFHGAQEFLQHRILNKMPPSFRCMVES--------VDVITRPKDTDARVCVWKGGSVLACLDTTQELWIHQREWQRFGVRMLRERAAFVW", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VX09-1", "uniprot_id": "ARP8_DROME", "id": "Q9VX09-1", "name": "Actin-related protein 8", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MQRSRASSTSSGRHPAPP--------------PIGLPQPQAQPLEAP---KIIVIHPGSQHLRIGRAADLNPLTLLHAVAYRRRPGASDRPHHDPLLPPLDNVNSNSGLMVEFEEQRLVVSRILQHCVVDNKNRLRVATPPQQLAHFNRSSQAEKVPAPSGQMADEPWLDREAPVLFDDRILRLGAVDARNYDIHFPIQRGELNVHNEKGGSLQASMQHLERIWSYALE-ERLKIPLRKLGTHCAVLVVNDVYVRRHLREFVTLLLRRLGFRRCFLVQDSVASTFGAGIG-YGCVVDIGAQKTSIACIEDGISQLDARVRLSYGGGDLDQVLLLLLRKCGFPYRECNVQESYVDAHLLDELKEKFCHLNASVCGAQEKHFNLRKHNGQWLRYTIQVGDEALMAPLALFHTELLNITGRTKAVFTQQAVQDQYD----CEDCFDAEYLKETGRKNGVRGGDILQLSTSAGYQPRPQLPVTADDEE--LIVVDQDETISNCQSQLG----AQTAGGQMNSNGCYHN------GQGLVLPLDQAIIQSINRLSS--------YETKRKMFGSILLVG----------SSAKLPGLAAWLEQRISQQVQSEVNVLIKG--------MDAG---------MVAWKGAAIMSVLESARELWISQNDWQRHGLRVLRERSPFLW", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q12386-1", "uniprot_id": "ARP8_YEAST", "id": "Q12386-1", "name": "Actin-like protein ARP8", "aln": "MSQEEAESSIIYEEPIDIPLEDDDDEDELEEENSVPLSSQADQENAENESDDSVDNVVGSETPRSVTGLSVDPRDVADEEDEDEEGEDEDEDEDDNDVDNEDENDNDNANENENELGSSRDKRAPPAVQTSKRYKKYPKLDPAKAPPGKKVPLHLLEKRRLGRIKAAEEFAKTLKKIGIEKVETTTLPATGLFQPLMLINQKNYSSDYLKKDDQIFALRDRKFLRNNNTSQISSTNTPDVIDLKSLPHSEASAAPLNDEIDLNDPTATIVIHPGSNSIKIGFPKDDHPVVVPNCVAVPKKWLDLENSEH------VENVCLQREQSEEFNNIKSEMEKNFRERMRYYKRKVPGNAHEQ-----VVSFNENSKPEIISEKNDPSPIEWIFDDSKLYYGSDALRCVDEKFVIRKPFRGGSFNVKSPYYKSLAELISDVTKLLEHALNSETLNVKPTKFNQYKVVLVIPDIFKKSHVETFIRVLLTELQFQAVAIIQESLATCYGAGISTSTCVVNIGAAETRIACVDEGTVLEHSAITLDYGGDDITRLFALFLLQSDFPLQDWKIDS-KHGWLLAERLKKNFTTFQDADVAVQLYNFMNRSPNQPTEKYEFKLFDEVMLAPLALFFPQIFKLIRTSSHKNSSLEFQLPESRDLFTNELNDWNSLSQFESKEGNLYCDLNDDLKILNRILDAHNIIDQLQDKPENYGNTLKENFAPLEKAIVQSIANASITADVTRMNSFYSNILIVGGSSKIPALDFILTDRINIWRPSLLSSASFPQFYKKLTKEIKDLEGHYVNAPDKTEDENKQILQAQIKEKIVEELEEQHQNIEHQNGNEHIFPVSIIPPPRDMNPALIIWKGASVLAQIKLVEELFITNSDWDVHGSRILQYKCIFTY", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : ... . . . : :: :*:**** :::* . * * : : :* :: .. :.: . : : . . : .: . : : * . : : :: *. * :*:: ** : .: : :*:: : *:: .: : :*:: *:: : *:. :: ::* .: * : *:*:.: :*:*:. *:*::* :* :.*:::* : : * ***.*: : : :: :..** :: :: . . * :.**:.* :: . * .* * : * ::: ** : **::**.. : : . .: .. :.. * . . . :. . : : : : . :. . .. :* : . :: . : :*: * : . ::.:* ::: . . : . :. :: : ", "identical_positions": 58, "similar_positions": 178, "identity": "6.49%" }, { "cls_id": "homologset.agr.MGI:1860776", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9VY08-1", "uniprot_id": "Q9VY08_DROME", "id": "Q9VY08-1", "name": "Glucose-methanol-choline oxidoreductase N-terminal domain-containing protein", "aln": "------------MVLNLLFITTVIKSTFGVV--------------------------TTGLWLIPLMLAAITYYRYD-AVDPESRPLDQLN--LYPEYDFIVVGSGSAGAVVANRLSEVRKWKVLLIEAGPDE-----NEISDVPSLAAYLQLSKLDWAYKTEPSTKACLGMQNNRCNWPRGRVLGGSSVLNYMLYVRGNRHDYDHWASLGNPGWDYDNVLRYFKKSEDNRNPYLANNK-YHGRGGLLTVQESPWHSPLVAAFVEAGTQLGYDNRD--INGAKQAGFMIAQGTIRRGSRCSTAKAFLRPIRMR-KNFHLSMNSHVTRVIIEPGTMRAQAVEFVKH-GKVYRIAARREVIISAGAINTPQLMMLSGLGPRKHLEKHGIRVLQDLP-VGENMQDHVGMGGLTFLVD----KPVAIVQDRFNPTAVTFQYVLRERGPMTTLGGVEGLAFVHTPYSNRSLDWPDIQFHMAPASINSDNGARVKKVLGLKESVYQEVYHPIANKDS--WTIMPLLLRPRSRGSVKLRSANPFHYPLINANYFDDPLDAKTLVEGAKIALRVAEAQVFKQFGSRLWRKPLPNCKQHKFLSDAYLECHVRTISMTIYHPCGTAKMGPAWDPEAVVDPRLRVYGVRGLRVIDASIMPTISSGNTNAPVIMIAEKGADLIKEDWLTNPEYKVKRQANRLRDPDPASSNIQGIITLPNNITQGDSSNISDRSNMESNFSNSSHINNINFNSNSNSSNIESSSNFTLNYANS", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VY00-1", "uniprot_id": "Q9VY00_DROME", "id": "Q9VY00-1", "name": "Glucose-methanol-choline oxidoreductase N-terminal domain-containing protein", "aln": "------------MSSAIVGAASAIGGAVTAA--------------------------TSNSWFIPMLMAAVAYFQYEEIIDPESKPSDVGGDDILDHYDFIVIGAGSAGAVVANRLTEVENWNVLLLEAGGDE-----TELTDVPLMAGYLQLSKIDWQYKTEPSGTSCLAMQGGRCNWPRGKVLGGSSVLNYMLYLRGSKHDYDNWEAMGNPSWSYRDALYYFKKSEDNTNQYLANTP-YHATGGYLTVGEAPYHTPLAASFVEAGVEMGYENRD--LNGEKMTGFMIAQGTTRRGSRCSTSKAFLRPARLR-PNLHISMNSHVTRIMIDPVTKLAFGVEFVKD-QKLYHVRATKEVVLSGGSVNSPQLLMLSGVGPRKELAKHRIPLIKELS-VGENLQDHIGLGGLTFLVN----QPVSIVENRFHTMSTVLQYAVFGQGPLTILGGVEGLAYVNTKYANSSLDWPDIEFHFVSGSTNSDGGSQLRKAHGLTDAFYRAVFEPINNRDA--WSIIPMLLRPRSVGNIRLRSGNPFDYPYIFPNYLTDDFDMKTLIEGVKIAVALSRTKAMQRFGSRISSIRWPGCEQVPLFTDAFWECMVRRYTSTIYHPVGTCKMGPYWDKDAVVDAKLRVYGIRGLRVIDASIMPKLVSANTNAPVIMIAEKGSDMIKEFWIKNTIV--------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VY06-1", "uniprot_id": "Q9VY06_DROME", "id": "Q9VY06-1", "name": "Glucose-methanol-choline oxidoreductase N-terminal domain-containing protein", "aln": "MVVVPALGAAAVSVGGLLFKASAASKAAAAAGVAAAGASKLGLAIAGAIKLATAVIGVGKLTILPFLIAAIAYYNYD-LFDPENRPFNVQQ--VDLAYDFIIIGGGSAGTVLASRLSEIPHWKILLLEAGGHE-----TEISDVPLLSLYLHKSKMDWKYRTQPQPTACQAMKDKRCCWTRGKVLGGSSVLNTMLYIRGNKRDFDQWADFGNPGWSYEDILPYFRKSEDQRNPYLARNKRYHGTGGLWTVQDAPYNTPIGPAFLQAGEEMGYDIVD--VNGEQQTGFGFYQFNMRRGSRSSTAKSFLRPARLR-PNLHVALFSHVTKVLTDPHTKRATGVQFIRD-GRLQNVYATREVILSAGAIGSPHLMMLSGIGHGEELGRVGIPLVQHLPGVGQNLQDHIAVGGIAFLID----YPISIVMKRMVNINTALRYAITEDGPLTSSIGLEAVAFINTKYANASDDWPDMNFMMTSASVMSDGGSQVKTAHGLTDEFYQEVFGEVNNRDV--FGVFPMMLRPKSRGYIKLASKNPLRYPLLYHNYLTHPDDVNVLREGVKAAVAMGETQAMKRFGARYWNKPVPNCKHLTLYTDDYWNCFIRQYTMTIYHMSGTAKMGPPTDPWAVVDPQLRVYGIPGLRVIDASIMPAITNGNIHAPVVMIGEKGADMIKQLWLTPTTAPVGVQG---QGPSPRQGHNTSPAPPPRTQWRSKRSLNSTEADTET--------------ENSENLDIGTSPVHQWPLPRS", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P18173-1", "uniprot_id": "DHGL_DROME", "id": "P18173-1", "name": "Glucose dehydrogenase [FAD, quinone]", "aln": "------MSASASACDCLVGVPTGPTLASTCG--------------------------GSAFMLFMGLLEVFIRSQCD-LEDPCGRASSRFRSEPDYEYDFIVIGGGSAGSVVASRLSEVPQWKVLLIEAGGDE-----PVGAQIPSMFLNFIGSDIDYRYNTEPEPMACLSSMEQRCYWPRGKVLGGTSVLNGMMYVRGNREDYDDWAADGNPGWAYNDVLPFFKKSEDNLDLDEVGTE-YHAKGGLLPVGKFPYNPPLSYAILKAGEELGFSVHD--LNGQNSTGFMIAQMTARNGIRYSSARAFLRPARMR-NNLHILLNTTATKILIHPHTKNVLGVEVSDQFGSTRKILVKKEVVLSAGAVNSPHILLLSGVGPKDELQQVNVRTVHNLPGVGKNLHNHV-----TYFTN----FFIDDADTAPLNWATAMEYLLFRDGLMSGTGISDVTAKLATRYAD-SPERPDLQLYFGGYLASCARTGQVGELLS-------------NNSRS--IQIFPAVLNPRSRGFIGLRSADPLEPPRIVANYLTHEQDVKTLVEGIKFVIRLSQTTPLKQYGMRLDKTVVKGCEAHAFGSDAYWECAVRQNTGPENHQAGSCKMGPSHDPMAVVNHELRVHGIRGLRVMDTSIMPKVSSGNTHAPAVMIAEKGAYLLKRAWGAKV----------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VY02-1", "uniprot_id": "Q9VY02_DROME", "id": "Q9VY02-1", "name": "Glucose-methanol-choline oxidoreductase N-terminal domain-containing protein", "aln": "-------------MSAINTFVAMWRFLLTLG---------------------------PSAMIILLLNKGILEQRPD-IVDEQHRVRSIHIEDLRESYDFIVIGGGSAGCVLAARLSENPEWSVLLLEAGGDE-----PLLIDLPQLYPVFQRSPWDWKYLTEPSDRYCLAMEDQRCFWPRAKVLGGCSSINAMMYIRGNRRDYDQWAALGNPGWNYDNILHYFRKLEDMRVPGFEHSP-YHGHGGPISVERYRFPSPLLDIFMRAAQQLGMVHPDGDFNGRSQTGFAPPHGSLRDGLRCSANKGYIRRSWQR-PNLDIVLKAFVERIVIDPQSHRAIGVIFEYG-LLKHTVRAKREVILSAGSLASPQLLMVSGVGPRDQLEPQGIPVVQHLPGVGGNLQDHISTSGAIYTFDSGQNRHLSFIVPEMMNEQAVEDFVQGSDSFFYAMPVSEVMGFFSTRYQDPRLDWPDVQIFMGSYGYGADGGMIGRRGAAITLDNYAEAFEPVLYQDS--FVIAPLLMRPRSRGYLQLRSADPKVHPLIHANYYDDPHDMAVMVEGLKLAHRLTQTPVMQSLNATMNIYEWRNCPEVEYLSDAFWECLARFYSQTIYHPVGTCKMAPASDPAGVVDPRLRVRGMRGLRVIDASIMPTIPTGNTNAPTLMLAERGADIIKEDWRHYRDGGWG-----------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VY11-1", "uniprot_id": "Q9VY11_DROME", "id": "Q9VY11-1", "name": "Glucose-methanol-choline oxidoreductase N-terminal domain-containing protein", "aln": "-------------MEKLLLTQLLFLLLIPLI-----------------------------HSQRSSQLDELRRLGLG--NVVNVPFFSD---VPQRNYDFIIVGGGAAGCTLAARLSENPNWSVFLIEAGGVE-----NIVHQVPLLAAHLQSTASNWGYNSTPQRHACRGMPDNKCALPRGKVLGGTSSINYMIYNRGNRRDFDAWAAAGNPGWSYDEVLPYFLRSEHAQLQGLEHSP-YHNHSGPLSVEDVRHRTRLAHAYIRAAQEAGHPRTD--YNGESQLGVSYVQATTLKGRRHSAFRAYIEPIRSRRHNLHILTLARVTRVLIDAATKSAYGVELTHQ-GRSFKVKARKEIILSAGAFNSPQLLMLSGIGPEDNLKAIGIPLIKALP-VGKRMFDHMCHFGPTFVTNTTG---QTLFAAQLGAPVAKEFLLGRADTFLSSIGGVETLTFIKVPSGKSPATQPDVELIQVAGSLASDDGTALAKGANFKPEIYEKMYKNLTLRQQDHFSFLIMHFKPASVGRLWLHNRNPLEWPRIDPKYFSAPSDVENLLEGIKEALRISKMPAMQAIGTRLLDKPVPGCENYEFASDDYWRCSIRTLSYTLHHQVATCRMGAESDPTTVVNHQLKVHGVRKLRVVDTSIIPFPPTAHTNAAAFMIGEKAADMIRSEWS-------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VBG8-1", "uniprot_id": "Q9VBG8_DROME", "id": "Q9VBG8-1", "name": "Glucose-methanol-choline oxidoreductase N-terminal domain-containing protein", "aln": "--------------MRFCGVLIICLWYIQVT-----------------------------WSQ--LLVDLARDFETS--FLNNRIPDTT---RFLPEYDFIIVGAGSAGCVMANRLSEISSASVLLLEAGDQE-----TFISDVPLTAALTQMTRYNWGYKAEPTEHACQGLKGGVCNWPKGRGVGGTSLINFMLYTRGHRRDYDEWAAANNSGWSYDELLPYFRKSERIGIPELYKSP-YHGRNGQLDVQYTDYRSQLLKAFLKSGREMGYEITD--PNGEHLMGFARSQATIRNGRRCSTSKAFIQPVVNR-KNLHISMKSWVTRLIIDPITKTATGVEFVKQ-RQRYVVRARKEVILSAGTIASPQLLMLSGIGPAEHLREHNITVMQDLP-VGYNLQDHITLNGLVFVVNDS-----TVNDARLLNPSDIFRYIFAGQGPYTIPGGAEAFAFVRTPSSKFAKDYPDMELVLGAGSLSGDRFGTMRNLLGITDEFYDYMFG--DLQSKETFGLVPVLLRPKSRGRISLRSRNPFHWPRMEPNFMQHPDDVRAMIEGIEMILKLSRSKPMAKMGTRFHDRPFPGCENLKFASEAYWKCCLRRYGSSLQHQSGTCKMGPATDNTSVVDAQLRIHGIRGLRVVDASVLPNVPAGHTNAIVIMVAEKAGDMIKDAWRMPITPLSS-----------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VY10-1", "uniprot_id": "Q9VY10_DROME", "id": "Q9VY10-1", "name": "Glucose-methanol-choline oxidoreductase N-terminal domain-containing protein", "aln": "-----MASKSLIFVG-LCLAYMATWSQISAQ-----------------------------NNN-NVLFETINFLRRG--QADVELENYDNNVILDSEYDFIVVGAGTAGCALAARLSENPQWRVLLLEAGGPE-----RLVMDVPIVAHFLQLGEMNWKYRTQPSDHACLAMNNNRCNWPRGKVMGGSSVLNYMMYTRGNRRDYDRWEALGNPGWSFKDVLPYFKKYEGSSVPDAEED--YVGRNGPVKVSYVNWRSKIAEAFVDAAQQDGLKYRD--YNGRIQNGVAFLHTTTRNSTRWSSNRAYLYPLKGKRSNLHVRKNALVTKVLIDPQTKTAYGIMVQTE-GRMQKILARKEVIVSAGAINTPQLLMLSGVGPAKHLREVGIKPLADLA-VGYNLQDHTAP-AVTFTTNAT-----SLKFEDFSDPTLINRFN-RMEGPYGSPGGCEAIAFWDLDHERDEDGWPDIELFLVGGSMSSN--PAISRAFGLKKSIYDTLFAEIEDKSLNAFMIFPMILRPKSRGRIMLKSSDPFKYPLIHANYFAHPYDVDISVRGLLKAISLMEQRGMEKINARLWEKKIPTCKQHPYKSWAYWACYVRHFTFTIYHYSGTAKMGPKSDRAAVVDHRLRVHGIKNLRVADASIMPEIMSGHPNGPVFMIAEKAADMIKQDHGFIQ----------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VY09-1", "uniprot_id": "Q9VY09_DROME", "id": "Q9VY09-1", "name": "Glucose-methanol-choline oxidoreductase N-terminal domain-containing protein", "aln": "-----MMTSPRNHIGTLLVVWLLEFSMVISQ-----------------------------TDTGNALMDMLEIYRRG--QAQLDLENLDEGQVITTKYDFIVVGAGTAGCALAARLSENPRWRVLLLEAGGPE-----NYAMDIPIVAHLLQLGEINWKYKTEPSNSYCLAMNNNRCNWPRGKVMGGSSVLNYMMYTRGNRRDYDRWARLGNPGWSYEEVLPYFKKYEGSVVPDADEN--LVGRNGPVKVSYSETRTRIADAFVGATQDAGLPRGD--YNGDKQIRVSYLQANIYNETRWSSNRAYLYPIKGKRRNLHVKKNALVTKILIDPQTKSAFGIIVKMD-GKMQKILARKEVILSAGAINTPQLLMLSGVGPAKHLREMGIKPLADLA-VGYNLQDHIAP-AISFLCNVS-----SLQTSEMFRSEAMSDFL-KGRGVLRIPGGVEAISFYALDDARNPDAWADMELFVVGGGLQTN--LALRLALGIQSNIYETMFGELERQSANGFLIFPMILRAKSRGRIKLKSRNPEEHPRIYANYFANPYDMNITVRGIEQAVSLLDMPAFKAIGAHLLEKRIPNCAKYKWKSSAYWACYARHFTFTIYHYSGTAKMGPRSDPSAVVDARLRVHGIDKLRVVDASIMPYLISGHPNGPVYLIAEKAADMIKEDHNFV-----------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q6UPE0-1", "uniprot_id": "CHDH_RAT", "id": "Q6UPE0-1", "name": "Choline dehydrogenase, mitochondrial", "aln": "----------------MWQVLRSWSKRCLSP------------------------------------RGALAWAAQGQPRPPCSCAVASAASGGKDEYTFIVVGAGSAGCVLANRLTEDPNHRVLLLEAGPKDLLMGSKRLQWKIHMPAALVANLCDDKYNWYYHTEAQPGLDGRVLYWPRGRVWGGSSSLNAMVYIRGHAEDYNRWHRQGAEGWDYAHCLPYFRKAQK----HELGANMYRGGDGPLHVSRGKTNHPLHQAFLQAARQAGYPFTED-MNGFQQEGFGWMDMTIHQGKRWSTASAYLRPALSR-PNLRAEVQTLVSRVLFEG--TRAVGVEYIKD-GQSHKAYVSREVILSGGAINSPQLLMLSGVGNADDLKKLGIPVVCHLPGVGQNLQDHLEIYIQHACTQ-------PITLHSAQKPLRKVCIGLEWLWRFTGDGATAHLETGGFIRSRPGVPHPDIQFHFLPSQVIDHG---------------------RKPTQQEAYQVHVGTMRATSVGWLKLRSTNPQDHPMINPNYLSTETDVEDFRQCVKLTREIFAQEAFAPFRGKELQ------PGSHVQSDKEIDAFVRAKADSAYHPSCTCKMGQPSDPTAVVDQQTRVIGVENLRVIDASIMPSVVSGNLNAPTIMIAEKAADVIKGCPALGDENVPVYKPQTLDTQR-------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8BJ64-1", "uniprot_id": "CHDH_MOUSE", "id": "Q8BJ64-1", "name": "Choline dehydrogenase, mitochondrial", "aln": "----------------MWQVLRGWRKGWQSP------------------------------------RGALAWAVQGQPCPPCSRAVASVG---KDEYTFVVVGAGSAGCVLASRLTEDPNHRVLLLEAGPKDLLMGSKRLQWKIHMPAALVSNLCDDKYNWYYHTEPQPGMDSRVLYWPRGRVWGGSSSLNAMVYIRGHAEDYNRWHREGAEGWDYAHCLPYFRKAQR----HELGANMYRGGDGPLHVSRGKTNHPLHQAFLQAARQAGYPFTED-MNGFQQEGFGWMDMTVHQGKRWSTACAYLHPVLSR-PNLRAEVQTLVSRVLFEG--TRAVGVEYIKD-GQRHKAYVSREVILSGGAINSPQLLMLSGVGNADDLRKLDIPVVCHLPGVGQNLQDHLEVYVQQACTQ-------PITLHSAQKPLRKVCIGLEWLWSYTGDGATAHLETGGFIRSRPGVPHPDIQFHFLPSQVIDHG---------------------RKPTQQEAYQVHVGTMRATSVGWLKLRSANPRDHPVIHPNYLSTETDVEDFRQCVRLSREIFAQEALAPFRGKELQ------PGSHVQSDKEIDAFVRAKADSAYHPSCTCKMGRSSDPTAVVDAQTKVIGVENLRVVDASIMPSVVSGNLNAPTVMIAEKAADIIKGHPALEDKNVPVYKPQTLDTQR-------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8NE62-1", "uniprot_id": "CHDH_HUMAN", "id": "Q8NE62-1", "name": "Choline dehydrogenase, mitochondrial", "aln": "----------------MWCLLRGLGR-----------------------------------------PGALARGALGQQQSLGARALASAGSESRDEYSYVVVGAGSAGCVLAGRLTEDPAERVLLLEAGPKDVLAGSKRLSWKIHMPAALVANLCDDRYNWCYHTEVQRGLDGRVLYWPRGRVWGGSSSLNAMVYVRGHAEDYERWQRQGARGWDYAHCLPYFRKAQG----HELGASRYRGADGPLRVSRGKTNHPLHCAFLEATQQAGYPLTED-MNGFQQEGFGWMDMTIHEGKRWSAACAYLHPALSR-TNLKAEAETLVSRVLFEG--TRAVGVEYVKN-GQSHRAYASKEVILSGGAINSPQLLMLSGIGNADDLKKLGIPVVCHLPGVGQNLQDHLEIYIQQACTR-------PITLHSAQKPLRKVCIGLEWLWKFTGEGATAHLETGGFIRSQPGVPHPDIQFHFLPSQVIDHG---------------------RVPTQQEAYQVHVGPMRGTSVGWLKLRSANPQDHPVIQPNYLSTETDIEDFRLCVKLTREIFAQEALAPFRGKELQ------PGSHIQSDKEIDAFVRAKADSAYHPSCTCKMGQPSDPTAVVDPQTRVLGVENLRVVDASIMPSMVSGNLNAPTIMIAEKAADIIKGQPALWDKDVPVYKPRTLATQR-------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "E7EY13-1", "uniprot_id": "E7EY13_DANRE", "id": "E7EY13-1", "name": "Choline dehydrogenase", "aln": "----------------MACFSS----------------------------------------------STRLMSSLCSP-LLHHRYISTVVNKNTPSYSYVIVGAGSAGCVLASRLTENPSDSVLLLEAGPKDKHLGSTRLSWKIHMPAALTYNLCDDRYNWFYHTLPQAHMDDRVMYWPRGRVWGGSSSLNAMVYIRGHAEDYNRWQSEGADGWNYDHCLPYFRKAQT----HELGPDRYRGGDGPLHVSRGKTQNPLHYAFIQAGQQAGYPYTED-MNGFQQEGVGWMDMTIHKGQRWSTASAYLRPALSR-PNLSTEVRCMVTRVLFDG--ARARGVEYQQN-GQIKKVFAEKEVILSGGAINSPQLLLLSGVGNADELKTLDIPVVQHLPGVGCNLQDHLELYVQHACTQ-------PITLYRAQKPLQMLKIGLEWLLKFTGYGATAHLESGGFIRSRPDVPHPDIQFHFLPSQVIDHG---------------------RVSSKIEAFQVHVGPMRSTSVGWLKLKSKDPRDHPILQPNYLSTETDVLEFRECVRLTREIFAQQAFDEFRGPEVQ------PGPAVQSDAEIDAFVRQKADSAYHPSCTCKMGRPEDRMAVVSPELRVFGVEGLRVVDASVMPSMVSGNLNAPTIMIAEKAADAIKGLPSLHDPGVPVYQPRKHP----------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : * ::::*.*:** .:* **:* ::*:*** : : * .:.: ** * :* *:* ** .*:: * . .* : . * :* : : .* * : : : : * : ** . . . * *: .:: : *: . ::: . . .: . :*:::*.*:. :*:::::**:* ..* : : *. ** .: :* .*::: . :. * * : * . :* * : :: * : : : . * . * :.:*. * **. . :: *: *** *:*::* .: :. . ::.*:.. :: ", "identical_positions": 68, "similar_positions": 120, "identity": "8.94%" }, { "cls_id": "homologset.agr.MGI:1860835", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9WTP7-1", "uniprot_id": "KAD3_MOUSE", "id": "Q9WTP7-1", "name": "GTP:AMP phosphotransferase AK3, mitochondrial", "aln": "-------MGASGRLLRAVIMGAPGSGKGTVSSRITKHF-ELKHLSSGDLLRQNMLQGTEIGVLAKTFIDQGKLIPDDVMTRLALHELKTLTQCS----WLLDGFPRTLPQAEALDKVYQ-----IDTVINLNVPFEVIKQRLTARWIHPASGRVYNIEFNPPKTVGIDDLTGEPLIQREDDKPETVIKRLKAYEAQTEPVLQYYQKKGVLETFSGTETNKIWPHVYSFLQTKVPETTQKASVTP", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P29411-1", "uniprot_id": "KAD3_RAT", "id": "P29411-1", "name": "GTP:AMP phosphotransferase AK3, mitochondrial", "aln": "-------MGASGRLLRAVIMGAPGSGKGTGSSRITKHF-ELKHLSSGDLLRQNMLQGTEIAVLAKSFIDQGKLIPDDDMTRLALHELKNLTQCS----WLLDGFPRTLPQAEALDRVYQ-----IDTVINLNVPFEVIKLRLTARWIHPASGRVYNIEFNPPKTVGIDDLTGEPLIQREDDKPETVIKRLKAYEAQTEPVLQYYQKKGVLETFSGTETNKIRPHVYSFLQMKVPETIQKASVTP", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9UIJ7-1", "uniprot_id": "KAD3_HUMAN", "id": "Q9UIJ7-1", "name": "GTP:AMP phosphotransferase AK3, mitochondrial", "aln": "-------MGASARLLRAVIMGAPGSGKGTVSSRITTHF-ELKHLSSGDLLRDNMLRGTEIGVLAKAFIDQGKLIPDDVMTRLALHELKNLTQYS----WLLDGFPRTLPQAEALDRAYQ-----IDTVINLNVPFEVIKQRLTARWIHPASGRVYNIEFNPPKTVGIDDLTGEPLIQREDDKPETVIKRLKAYEDQTKPVLEYYQKKGVLETFSGTETNKIWPYVYAFLQTKVPQRSQKASVTP", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VGU6-1", "uniprot_id": "KAD3_DROME", "id": "Q9VGU6-1", "name": "GTP:AMP phosphotransferase, mitochondrial", "aln": "---------MFTKIFRAVIIGAPGSGKGTISELICKNH-GCVHISTGDILRQNIIKNTELGKKAKQYIAEGKLVPDAIVTKTMLARITEVGNRS----YILDGFPRNIAQAEALAAREQ-----IDAVITLDVPHSVIIDRVKNRWIHAPSGRVYNIGFKNPKVPGKDDVTGEPLMQREDDKPHVVAKRLELYDEVMSPVIAWYEKKGLVATFKGKQTKEIWPMMELFLNDRINA---------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P26364-1", "uniprot_id": "KAD3_YEAST", "id": "P26364-1", "name": "GTP:AMP phosphotransferase, mitochondrial", "aln": "MKADAKQITHLLKPLRLLLLGAPGSGKGTQTSRLLKQIPQLSSISSGDILRQEIKSESTLGREATTYIAQGKLLPDDLITRLITFRLSALGWLKPSAMWLLDGFPRTTAQASALDELLKQHDASLNLVVELDVPESTILERIENRYVHVPSGRVYNLQYNPPKVPGLDDITGEPLTKRLDDTAEVFKKRLEEYKKTNEPLKDYYKKSGIFGTVSGETSDIIFRNY-------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : :* :::********* :. : .: :*:**:**::: : :. *. :* :***:** :*: .:. : . ::******. .**.** : :: *: *:** ..* *: *::* .******: :: **. * **:***** :* **..... ***: *. .*: :*:*.*:. *..* :. * ", "identical_positions": 71, "similar_positions": 70, "identity": "29.1%" }, { "cls_id": "homologset.agr.MGI:1861032", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I6B330-1", "uniprot_id": "A0A8I6B330_RAT", "id": "A0A8I6B330-1", "name": "", "aln": "MEGGVQAPSLAGRPSRVAVILTEGQASYKVPDNCWSYSVGDRHFRESLSGILCGAAQNPHGFSQLRSHLLLMAGMAENTAAEHPLFTGASCVLVFLSCLGSTLCADVHSLSCNLIIRSPTKAEPLWYEGQCSMDGNVFLSSNNVNKTMP-LGNQEKMANATEVWTCLTQWIDRCKQDLRDKVSEIKGDTTKTSGHPTLRVTMLSNHSHEQIIGASCVFNISENYSFILDLKTMKWKLINPVPEDIMKEWKDDKTLMKHLN-LFIVECSPKFNEFLNQHEERTRSTTRAPDITQP------PPTSQVPYKEVLIPVGLIISIIFIIFLCICVKRMCCPHGGRELQLLKDYCINWHKPQRNEGLEETKGEVPNQRTKMLSQEEDPKTLGGPRRASESVELELQMFSSTGS-------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0A8I6GMP0-1", "uniprot_id": "A0A8I6GMP0_RAT", "id": "A0A8I6GMP0-1", "name": "", "aln": "---------------------------------------------------MCPMAL----CSQFGTHLHVSL-------------------------------TDVHSFSCNLIIRAPTKAEPLWYEGQCSVDGIDFLSSNNVNKTMP-LGNQEKMANATEVWTCEIQWLDLLGQDLRDKVSEIKVHTTKTSGHPTLRVTMLSKHRHGQIISASWEFNISENYSFILDLKNMKW-----IPEDIMKEWKDDATLMKHLN-LFIVECSPKFNEFLNQHEERTRSTTRAPDITQP------PPTRQFPYKEVLIPV---VLIIFIIFICICVKRMCCPQGGRELQLLKDYCINFHKPQRNEGLEETRGEVPNQRTKILSQEEDPKTLGGPRRASDPVELELHMVLSTGS-------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0A8I5ZTU3-1", "uniprot_id": "A0A8I5ZTU3_RAT", "id": "A0A8I5ZTU3-1", "name": "", "aln": "----------------------------------------------------MTMAKRGTTKCNLSLSLGLLLLLN---------------------FLGTAMLEDVHSLSCNLIIRSPTKAEPLWYEGQCSMDGIDFLSFNNVNKTMP-LGNQEKMANATEVWTCVTQWIDLLGQDLRDKVSEIKGDTTKTSGHPTLWVTMLSNHSHRHIIGASCVFNISENYSFILDLKTMKWKLINPVPEDIMKEWKDDATLMKHLN-LSIAECSQKFNEFLNQHEERTRSRTRAPDIAQP------PPTRQFPYKEVLIPV---VLIIFIIFICICVKRMCCTQGGRELQLLKDYYINLHKPQRNEGLEETKGEVPNQSTKMLSQEEDPKTLGGPRRASESVELELQMFSSTGS-------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9JI58-1", "uniprot_id": "RAE1D_MOUSE", "id": "Q9JI58-1", "name": "Retinoic acid early-inducible protein 1-delta", "aln": "----------------------------------------------------MAKAAVTKRHHFMIQKLLILLSYG-----------------------YTNGLDDAHSLRCNLTIKAPTPAD----EVKCFVGEILILHLSNINKTMT-SGDPGETANATEVGECLTQPLKDLCQKLRDKVSNTKVDTHKTNGYPHLQVTMIYPQSQGQTPSATWEFNISDSYFFTFYTEIMSWRSANDESGVIMNKWKDDGEFVKQLK-FLIHGCSQKMDEFLKQSKEKPRSTSRSPSITQLTSTSPLPPTSHSTSKKGFISVG----LIFISLLFAFAFAM---------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q5VY80-1", "uniprot_id": "ULBP6_HUMAN", "id": "Q5VY80-1", "name": "UL16-binding protein 6", "aln": "----------------------------------------------------MAAAAIPALLLCLPLLFLLFGWSR-------------------------ARRDDPHSLCYDITVIPKFRPGPRWCAVQGQVDEKTFLHYDCGNKTVTPVSPLGKKLNVTMAWKAQNPVLREVVDILTEQLLDIQLENYTPKEPLTLQARMSCEQKAEGHSSGSWQFSIDGQTFLLFDSEKRMWTTVHPGARKMKEKWENDKDVAMSFHYISMGDCIGWLEDFLMGMDSTLEPSAGAPLAMSSG-----TTQLRATATTLILCC----LLIIL------------------------------PCFILPGI-----------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9BZM5-1", "uniprot_id": "ULBP2_HUMAN", "id": "Q9BZM5-1", "name": "UL16-binding protein 2", "aln": "----------------------------------------------------MAAAAATKILLCLPLLLLLSGWSR-------------------------AGRADPHSLCYDITVIPKFRPGPRWCAVQGQVDEKTFLHYDCGNKTVTPVSPLGKKLNVTTAWKAQNPVLREVVDILTEQLRDIQLENYTPKEPLTLQARMSCEQKAEGHSSGSWQFSFDGQIFLLFDSEKRMWTTVHPGARKMKEKWENDKVVAMSFHYFSMGDCIGWLEDFLMGMDSTLEPSAGAPLAMSSG-----TTQLRATATTLILCC----LLIIL------------------------------PCFILPGI-----------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6H3X3-1", "uniprot_id": "ULBP5_HUMAN", "id": "Q6H3X3-1", "name": "UL-16 binding protein 5", "aln": "----------------------------------------------------MAAAASPAFLLRLPLLLLLSSWCR-------------------------TGLADPHSLCYDITVIPKFRPGPRWCAVQGQVDEKTFLHYDCGSKTVTPVSPLGKKLNVTTAWKAQNPVLREVVDILTEQLLDIQLENYIPKEPLTLQARMSCEQKAEGHGSGSWQLSFDGQIFLLFDSENRMWTTVHPGARKMKEKWENDKDMTMSFHYISMGDCTGWLEDFLMGMDSTLEPSAGAPPTMSSG-----TAQPRATATTLILCC----LLIMCLLICSRHSLTQSHGHHPQSLQPPPHPPLLHPTWLLRRVLWSDS-YQIAKRPLSGGHVTRVTLPIIGDDSHSLPCPLALYTINNGAARYSEPLQVSIS", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8TD07-1", "uniprot_id": "RAE1E_HUMAN", "id": "Q8TD07-1", "name": "Retinoic acid early transcript 1E", "aln": "----------------------------------------------------MRRISLTSSPVRLLLFLLLLLIAL-------------------------EIMVGGHSLCFNFTIKSLSRPGQPWCEAQVFLNKNLFLQYNSDNNMVKPLGLLGKKVYATSTWGELTQTLGEVGRDLRMLLCDIKPQIKTS-DPSTLQVEMFCQREAERCTGASWQFATNGEKSLLFDAMNMTWTVINHEASKIKETWKKDRGLEKYFRKLSKGDCDHWLREFLGHWEAMPEPTVSPVNASDIH-----WSSSSLPDRWIILGA----FILLVLMG-----------------------------IVLICVWWQNGEWQAGLWPLRTS------------------------------------------", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : : . **: :: : . . : :. :* . .: : . : .* . : * : : : . . * . * : ..: : . . : : * . : : *:.* . :. : * : :** . .. . . . . :: ::: ", "identical_positions": 13, "similar_positions": 61, "identity": "3.09%" }, { "cls_id": "homologset.agr.MGI:1861099", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I5YBG5-1", "uniprot_id": "A0A8I5YBG5_RAT", "id": "A0A8I5YBG5-1", "name": "E3 ubiquitin-protein ligase", "aln": "-MASEMEPEVQ-AIDRSLLECSAEEIAGKWLQATDLTREVYQHLAHCVPKIYCRGPNPFPQKE----------------DTLAQHILLGPMEWYICGEDPALGFPKLEQA------NKPSHLCGRVFKVGEPTYSCRDCAVDPTCVLCMQCFLGSIHRDHRYR--MTTSGGGGFCDCGDTEAWKEGP---YCQRHELS-------------SSEVVEEEDPLVHLSEDVIARTYNIFAIMFRYAVDMLTWEKESELPEDLEVGEKT---------------------------------------------DTYYCMLFNDEV-HTYEQVIYTLQKAVNCTQKEAIGFATTVDRDGRRSVRYG--------------------------DFQYCDQAKTVIVR-------------NTSRQTKPLKVQVMHSSVAAHQNFGLKALS---------WLGSVIGYSDGLRRILCQVGLQEG-----------------------------PDGENSSLVDRLMLNDSKLWKGARSVYHQLFMSSLLMDLKYKKLFAVRFAKNYRQLQRDFMEDDHER-AVSVTALSVQFFTAPTLARMLITEENLMTVIIKAFMDHLKHRDAQGRFQFERYTALQAFKFRRVQSLILDLKYVLISKPTEWSDELRQKFLQGFDAFLELLKCMQGMDPITRQVGQHIEMEPEWEAAFTLQMKLTHVISMVQDWCALDEKVLIEAYKKCLAVLMQCHGGFTDGEQPITLS---------------------------ICGHSVETIRYCVSQEKVSIHLPISRLLAGLHVLLSKSEVAYK---FPELLPLSELSPPM-----LIEHPLRCLVLCAQVHAGMWRRNGFSLVNQIYYYHN-VKCRREMFDKDIVMLQTGVSMMDPNHFLMIMLSRFELYQIFSTPDYGKRFSSEVTHKDVVQQNNTLIEEMLYLIIMLVGERFSPGVGQVGATDEIKREIIHQLSIKPMAHSELVKSLPEDE--NKETGMESVIETVAHFKKPG-LTGRGMYELKPECAKEFN-LYFYHFSRAEQSKAEEAQRKLKRENK---EDTALPPPALPPFCPLFGSLVNILQCDVMLSIMGTILQWAVERHGSAWSESMLQRVLHLIG--MALQEEKHHLENAVEGHVQT-FTFTQKISKPGDAPNNSPSILAMLETLQNAPSLEVHKDMIRWLLKMFNTIKKIRESSSSSP----VAEAEGA---IMEESSRDKDKAERKRKAEIARLRREKIMAQMSEMQRHFIDENKELFQQTIE-LDASASAA-----------LDNSPLVPDAALTALGPAQTQVP--EPRQFVTCILCQEEQEVTVESRAMVLAAFVQRSTVLSK---DRSKVIEDPEKYDPLFMHPDLSCGTHTGSCGHAMHAHCWQRYFDSVQAKEQRRQQRLRLHTSYDVENGEFLCPLCECLSNTVIPLLLPPRSILSRRLNFSDQPDLAQWTRTIAQQIKVIQMLRKGDSAADKPSSEDT---------EDMNIIPIPEGFRPDFYPRN-------PYSDSIKEMLTTFG--TATYKVGLKVHPNEDDPRVPIMCWGTCAYTIQSIERILSEEEKPVFGPLPCRLDDCLRSLTRFAAAHWTVALLP-----VVQGHFCKLFASLVPSDGSEDLPCILDIDMFHLLVGLVLSFPALQCQDFSGSSLATG--------DLHIFHLVTLAHIVQILLTSCTEENGMDQEN--PTGEE---------------------------ELAILSLHKTLHRCTGSALDEAPSG--------------WHLWRSVRAGILPFLKCSALFFHYLNGVPAPPDLQVSGASHFEHLCNYLSLPTNLIRLFQENSDIMNSLIESWCQNSEVKRYLNG--------ERGAISYPRGANKLIDLPEDYSSLINQASNFSCPKSGGDKSRAPTLCLVCGSLLCSQSYCCQAELEGEDVGACTAHTYSCGSGAGIFLRVRECQVLFLAGKTKGCFYSPPYLDDYGETDQGLRRGNPLHLCQERFRKIQKLWQQHSITEEIGHAQEANQTLVGIDWQHL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q6WKZ8-1", "uniprot_id": "UBR2_MOUSE", "id": "Q6WKZ8-1", "name": "E3 ubiquitin-protein ligase UBR2", "aln": "-MASEMEPEVQ-AIDRSLLECSAEEIAGRWLQATDLNREVYQHLAHCVPKIYCRGPNPFPQKE----------------DTLAQHILLGPMEWYICAEDPALGFPKLEQA------NKPSHLCGRVFKVGEPTYSCRDCAVDPTCVLCMECFLGSIHRDHRYR--MTTSGGGGFCDCGDTEAWKEGP---YCQKHKLS-------------SSEVVEEEDPLVHLSEDVIARTYNIFAIMFRYAVDILTWEKESELPEDLEVAEKS---------------------------------------------DTYYCMLFNDEV-HTYEQVIYTLQKAVNCTQKEAIGFATTVDRDGRRSVRYG--------------------------DFQYCDQAKTVIVR-------------NTSRQTKPLKVQVMHSSVAAHQNFGLKALS---------WLGSVIGYSDGLRRILCQVGLQEG-----------------------------PDGENSSLVDRLMLNDSKLWKGARSVYHQLFMSSLLMDLKYKKLFALRFAKNYRQLQRDFMEDDHER-AVSVTALSVQFFTAPTLARMLLTEENLMTVIIKAFMDHLKHRDAQGRFQFERYTALQAFKFRRVQSLILDLKYVLISKPTEWSDELRQKFLQGFDAFLELLKCMQGMDPITRQVGQHIEMEPEWEAAFTLQMKLTHVISMVQDWCALDEKVLIEAYKKCLAVLTQCHGGFTDGEQPITLS---------------------------ICGHSVETIRYCVSQEKVSIHLPISRLLAGLHVLLSKSEVAYK---FPELLPLSELSPPM-----LIEHPLRCLVLCAQVHAGMWRRNGFSLVNQIYYYHN-VKCRREMFDKDIVMLQTGVSMMDPNHFLMIMLSRFELYQLFSTPDYGKRFSSEVTHKDVVQQNNTLIEEMLYLIIMLVGERFNPGVGQVAATDEIKREIIHQLSIKPMAHSELVKSLPEDE--NKETGMESVIESVAHFKKPG-LTGRGMYELKPECAKEFN-LYFYHFSRAEQSKAEEAQRKLKRENK---EDTALPPPALPPFCPLFASLVNILQCDVMLYIMGTILQWAVEHHGSAWSESMLQRVLHLIG--MALQEEKHHLENAVEGHVQT-FTFTQKISKPGDAPHNSPSILAMLETLQNAPSLEAHKDMIRWLLKMFNAIKKIRECSSSSP----VAEAEGT---IMEESSRDKDKAERKRKAEIARLRREKIMAQMSEMQRHFIDENKELFQQTLE-LDTSASAT-----------LDSSPPVSDAALTALGPAQTQVP--EPRQFVTCILCQEEQEVTVGSRAMVLAAFVQRSTVLSK---DRTKTIADPEKYDPLFMHPDLSCGTHTGSCGHVMHAHCWQRYFDSVQAKEQRRQQRLRLHTSYDVENGEFLCPLCECLSNTVIPLLLPPRSILSRRLNFSDQPDLAQWTRAVTQQIKVVQMLRRKHNAADTSSSEDT---------EAMNIIPIPEGFRPDFYPRN-------PYSDSIKEMLTTFG--TAAYKVGLKVHPNEGDPRVPILCWGTCAYTIQSIERILSDEEKPVFGPLPCRLDDCLRSLTRFAAAHWTVALLP-----VVQGHFCKLFASLVPSDSYEDLPCILDIDMFHLLVGLVLAFPALQCQDFSGSSLATG--------DLHIFHLVTMAHIVQILLTSCTEENGMDQEN--PTGEE---------------------------ELAILSLHKTLHQYTGSALKEAPSG--------------WHLWRSVRAAIMPFLKCSALFFHYLNGVPAPPDLQVSGTSHFEHLCNYLSLPTNLIHLFQENSDIMNSLIESWCQNSEVKRYLNG--------ERGAISYPRGANKLIDLPEDYSSLINQASNFSCPKSGGDKSRAPTLCLVCGSLLCSQSYCCQAELEGEDVGACTAHTYSCGSGAGIFLRVRECQVLFLAGKTKGCFYSPPYLDDYGETDQGLRRGNPLHLCQERFRKIQKLWQQHSITEEIGHAQEANQTLVGIDWQHL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8IWV8-1", "uniprot_id": "UBR2_HUMAN", "id": "Q8IWV8-1", "name": "E3 ubiquitin-protein ligase UBR2", "aln": "-MASELEPEVQ-AIDRSLLECSAEEIAGKWLQATDLTREVYQHLAHYVPKIYCRGPNPFPQKE----------------DMLAQHVLLGPMEWYLCGEDPAFGFPKLEQA------NKPSHLCGRVFKVGEPTYSCRDCAVDPTCVLCMECFLGSIHRDHRYR--MTTSGGGGFCDCGDTEAWKEGP---YCQKHELN-------------TSEIEEEEDPLVHLSEDVIARTYNIFAITFRYAVEILTWEKESELPADLEMVEKS---------------------------------------------DTYYCMLFNDEV-HTYEQVIYTLQKAVNCTQKEAIGFATTVDRDGRRSVRYG--------------------------DFQYCEQAKSVIVR-------------NTSRQTKPLKVQVMHSSIVAHQNFGLKLLS---------WLGSIIGYSDGLRRILCQVGLQEG-----------------------------PDGENSSLVDRLMLSDSKLWKGARSVYHQLFMSSLLMDLKYKKLFAVRFAKNYQQLQRDFMEDDHER-AVSVTALSVQFFTAPTLARMLITEENLMSIIIKTFMDHLRHRDAQGRFQFERYTALQAFKFRRVQSLILDLKYVLISKPTEWSDELRQKFLEGFDAFLELLKCMQGMDPITRQVGQHIEMEPEWEAAFTLQMKLTHVISMMQDWCASDEKVLIEAYKKCLAVLMQCHGGYTDGEQPITLS---------------------------ICGHSVETIRYCVSQEKVSIHLPVSRLLAGLHVLLSKSEVAYK---FPELLPLSELSPPM-----LIEHPLRCLVLCAQVHAGMWRRNGFSLVNQIYYYHN-VKCRREMFDKDVVMLQTGVSMMDPNHFLMIMLSRFELYQIFSTPDYGKRFSSEITHKDVVQQNNTLIEEMLYLIIMLVGERFSPGVGQVNATDEIKREIIHQLSIKPMAHSELVKSLPEDE--NKETGMESVIEAVAHFKKPG-LTGRGMYELKPECAKEFN-LYFYHFSRAEQSKAEEAQRKLKRQNR---EDTALPPPVLPPFCPLFASLVNILQSDVMLCIMGTILQWAVEHNGYAWSESMLQRVLHLIG--MALQEEKQHLENVTEEHVVT-FTFTQKISKPGEAPKNSPSILAMLETLQNAPYLEVHKDMIRWILKTFNAVKKMRESSPTSP----VAETEGT---IMEESSRDKDKAERKRKAEIARLRREKIMAQMSEMQRHFIDENKELFQQTLE-LDASTSAV-----------LDHSPVASDMTLTALGPAQTQVP--EQRQFVTCILCQEEQEVKVESRAMVLAAFVQRSTVLSK---NRSKFIQDPEKYDPLFMHPDLSCGTHTSSCGHIMHAHCWQRYFDSVQAKEQRRQQRLRLHTSYDVENGEFLCPLCECLSNTVIPLLLPPRNIFNNRLNFSDQPNLTQWIRTISQQIKALQFLRKEESTPNNASTKNS---------ENVDELQLPEGFRPDFRPKI-------PYSESIKEMLTTFG--TATYKVGLKVHPNEEDPRVPIMCWGSCAYTIQSIERILSDEDKPLFGPLPCRLDDCLRSLTRFAAAHWTVASVS-----VVQGHFCKLFASLVPNDSHEELPCILDIDMFHLLVGLVLAFPALQCQDFSGISLGTG--------DLHIFHLVTMAHIIQILLTSCTEENGMDQEN--PPCEE---------------------------ESAVLALYKTLHQYTGSALKEIPSG--------------WHLWRSVRAGIMPFLKCSALFFHYLNGVPSPPDIQVPGTSHFEHLCSYLSLPNNLICLFQENSEIMNSLIESWCRNSEVKRYLEG--------ERDAIRYPRESNKLINLPEDYSSLINQASNFSCPKSGGDKSRAPTLCLVCGSLLCSQSYCCQTELEGEDVGACTAHTYSCGSGVGIFLRVRECQVLFLAGKTKGCFYSPPYLDDYGETDQGLRRGNPLHLCKERFKKIQKLWHQHSVTEEIGHAQEANQTLVGIDWQHL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1QLF4-1", "uniprot_id": "A0A8M1QLF4_DANRE", "id": "A0A8M1QLF4-1", "name": "E3 ubiquitin-protein ligase", "aln": "MAAAETDRDAPSALCSEFLNFSAKDTAAKWLQVSNLPKEVYQHLACYVPKIYCLGPNLNPQNE----------------DLLAQLLLQGPLEWYLCGEEPSVGLSKLEQN------NQPSQLCGHVFKVGEPTYSCRECAADPTCVLCMQCFLGSVHKEHRYR--MTTSGGGGFCDCGDTEAWKKGP---YCQKHEPN-------------ISDS-SQKDPLANLSAEMIARTYNVFSIILKYAVDMLTWDKEDELPEGLEPPARG---------------------------------------------DMYYCMLFNDEV-HTYEQVIYTLQKAVNCTQKEAVSFATTVDRDGRKSVRFG--------------------------DFQFCEQAKSVIVR-------------NTSRQTKPLRVQVMHSSVVAHQCFALKALN---------WLGQTIRYSDALRRILCQVGLQRG-----------------------------PEGENSSLVDKLMLCDSKMWKGARNVYHQLFMSSLLMDPKYKKLFAIQFARSYQRLQTDFMEDDHER-VVSVTSLSVQLFTAPTVARMLITDENLMTTIIRTFVDHLRHRDLQGRFQFERYTAQQAFKFRRVQSLIGDLKYVLISRPTEWTDQLREKYLEGFDAFLELLKCMQGMDPVVRQVGQHIEMEPEWEAAFTLQMKLTHIISMMQEWCASDERVLIEAYKKSLSALTHCHSGFTDGEQPITLS---------------------------MCGHSVDTIRYCVSQEKVSIHLPVSRLLAGLHALLSKIEVAYR---FPEQLPLSELSPPM-----LIEHPLRCLVLCAQVHAGMWRRNGFSLVNQIYYYHN-VKCRVEMFDKDLIMLQAGASMMDPNHFLMIMLSRFELYHIFSSADCRKRYSRENANKDVVQQNNTLIEEMLHLIIMIVGERYTAGVGQVEITDEIRREIVHQLCIRPMAHSELVKALPENE--NKETGMERVIDSVALFKKPG-VTGRGLYKLRPECAKMFN-LYFHHYSRADQSKAEEAQRKIKRQNG---EDSVLPPPVLPRFCPLFASLVNILQCDVLLGILGAVLQWAMEPSGGHWSESMLQRVLHLIG--MGLVEEQQHLISSAEDYNDTNFNFTLKISRPGEAPANTASILALLETLQNAPHLEVHKDMIRWILKTVAYIKTTRECTASSP----PSDSSGH---SQEETVRDKEKAERKRKAEMARLRREKIMAQMSEMQRHFINENKELFQQSLEDLDPSTSST-----------LEHSPSSCDSALVCVGPRRWRAGGSDRRQVVTCILCQEEQEIRSDGKAMVLAAFVQRSTVMSK---NRKRPPHNPDKYDPLFMHPDLSFGTHTGSCGHIMHSHCWQRYFEAVQAKEQRRQQRLRVHTSYDVENGEFLCPLCECLSNTVIPLLPLTKTCCS-----SEQPDLSQWLNITSHQMKALISAHRKSKASSAEAADET---------DGVNDCPPPDGFRLDHTPKN-------PYSSTIKEMLTTFG--TATYKVGLKVHPNEQDPRVPIMCWGSCAYTIQSIERLLVDEEKPLFGSLPCRQDDCLSSLTRFGSACWTVSSHT-----TVQNHFIRLLAALVPDPRVENSPCILDVDMFHLLVSLVLSHPAVLCLDSSGLSADAA--------QLHFLHLITVAHVVQILLTSLPEEVRMEQETGGAEREE---------------------------EESVCLLYNTLRSLLGRGLREVSSG--------------WHLWLCVKAGILPYLRAAALFFHYLNGAPAPPELHALGAGEWEALCGYLCLPSNLLQLYFNNLDIMEPLLHGWCSHP-ALQALQS--------SVTLIRFPRESNHLIDLPGDYSALINQASSFTCPKSGGDKSRVPTLCLVCGAMLCSQSYCCQTELEGEDVGACTAHTFTCGAGVGIFLRVRESQVLFLAGKTKGCFYAPPYLDDYGETDQGLRRGNPLHLCHERYRKIQKLWRQHSITEEIGHAQEANQTLVGIDWQHL", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VX91-1", "uniprot_id": "UBR1_DROME", "id": "Q9VX91-1", "name": "E3 ubiquitin-protein ligase UBR1", "aln": "--MDRYDMEDVVVAPPAECSSPLKEWRLKRQAGTLDRSDIIEFLKRESPKYFDYQTSATVKDTNVIT------LKCMFKESLAKEEIIDVVVEFMLGDNPSSALEKLRLE------GNTATVCGKVFKNGEPTYSCRECGVDPTCVLCVNCFKRSAHRFHKYK--MSTSGGGGCCDCGDDEAWKKDQ---YCELHLAN-------------RKNPLESKILTDAVLERVEICFGAILAFCVSYLEIEPNASLQCLDGNVEGGQVDG---------------------------------------------AQYCTVLYNDES-HTFDQVIQTLTKIAKCRAKDAMEIVAAIDREGRAVVKCD--------------------------TFEECNKLKVSIENQMILP----TSLVSTARNNQSLRTSVLHIGAVACQQFALQLLG---------WFQEFLVRHYLFRKTFSELVQRK---------------------------------QETFCIRHILEYDVKLWKTARTCWHRLLISGMLMEYDNKMILAQEFSRRYATIVEDFISDDHDH-AFSIVSLSVQLFTVPSIAHHLIAHEGIFDKLLHTFYHVAIEKFIRNKTLHFSKNIASLTFFKRANYILYDLRYLLSLKPDVLSNDLRNGFLEGCRALMRVLNVMQGMESMTRQTGQHMDYEPEWECAFNLHIKLATTISQVIDWASGDVKLLRKLYKMTMRALVSNSFIVGGEKVMQPKK---------------------------VADHVANCLVYDISVQPVSIHLPLSRFFAGIYLHLGAHDLTYDGLQTETEALSIKLTPRE-----IIEPVLCTQAMIAQVGAGLWRRNGYTLLHQLYFYRN-VRCRVEMLDRDIACLQIGASLMESNEFLIHVLNRFNTIPWLQENYWSLLSGNE--MNDDIIREASIFDEFLELLIVIIGERWMPGVSMVTEEDRLRKEIIQLLCIKPYSHSELSRALPDGNSGNSDNVFEEVINTVAVFKKPVGADSKGVYELKEHLLKEFN-MYFYHYTKEDKSKAEELQRERRKAKK---QLVCCPPPMLPKLTPAFTPMANILQCPVFLNICSLIMERALNAYSRSFTESHLQKVLHLLG--YAIQEELSEHYPFLSFYERS----------------QEYGILEKLEELARCPRLEAHYDFVLWTIERFKQLQAKQAPSDGRAGPSCSQQGTGG---KLSLSAEEQAREERENRARLAAERRAHIMAQMQKAQKSFISSNAEMFADTENETRKESASTGPMDWEDIPPEEEQGAVALESKVACLGPDRKFYHG--TDDTFKCILCFENCAISRGGRQLVSSAFVQTSRVIFT---TPN--------------LRNSQSALHISCCGHVMHYSCWLEYFTNEEFKELRRPHRNRAALAQAAN-VEFQCPYCRTLSNAIIPVTETLPAFSAPPSPNESYLPLDSFVEIMSTLAIELGNVKDHELTTLPSVSNIL---------RLSGVVGGLAQFERSVQLIKNPPRLHADYIEGIEFLKKALLNTMKIQQSHLKDHPAIESIEMVPILWDSCSYTLQALEIYLYAVEKPLKAELSMRHQSCARNLVRACSRSSALEWETDLPLLPPMRSQAEFSSRLLDTIFNQNDTSVLEWDCFRVLVPFQFGVLNLMVPEKGYKTIIPSGSM----FDFYIMQTMFLAQLTKAVLCFDVEKEKAKRAEKAPNSELTQLDYIEQLPSRIRDNMID---FYRRYNIPARVLQKTKQKQLVEEESEENQGHGQTVVIPCESHHLALLLEYVQRQMSSFLRCSCLFYRFLTDVDFPDTFPTDQPDRFDLMCQYLGLDP-MLGVYFDMETVYATMMHSFASHPHIDREVEQRCQPDARRSLQVEPCLRPLPRLKVLCDDFSDLINSVSDIFCPNNEREEMKTPTMCLICGLILCGQSYCCQPELGKVSVGACTHHAHACGAEVGIFLRIRDCQVVYLG-RGKGCFVPPPYLDEYGETDMGLRRGNPLRLSQAAYRKIYLQWLGHGLHGEIARLNDNANVAAAAQWHHM", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P19812-1", "uniprot_id": "UBR1_YEAST", "id": "P19812-1", "name": "E3 ubiquitin-protein ligase UBR1", "aln": "MSVADDDLGSLQGHIRRTLRSIHNLPYFRYTRGPTERADMSRALKEFIYRYLYFVISNSGENLPTLFNAHPKQKLSNPELTVFPDSLEDAVDIDKITSQQTIPFYKIDESRIGDVHKHTGRNCGRKFKIGEPLYRCHECGCDDTCVLCIHCFNPKDHVNHHVCTDICTEFTSGICDCGDEEAWNSPL---HCKAEEQENDISEDPATNADIKEEDVWNDSVNIALVELVLAEVFDYFIDVFNQNIEPLPTIQKDITIKLREMTQQGKMYERAQFLNDLKYENDYMFDGTTTAKTSPSNSPEASPSLAKIDPENYTVIIYNDEY-HNYSQATTALRQGVPDNVHIDL-LTSRIDGEGRAMLKCSQDLSSVLGGFFAVQTNGLSATLTSWSEYLHQETCKYIILWITHCLNIPNSSFQTTFRNMMGKTLCSEYLNATECRDMTPVVEK---------YFSNKFDKNDPYRYIDLSILADGNQIPLGHHKILPESSTHSLSPLINDVETPTSRTYSNTRLQHILYFDNRYWKRLRKDIQNVIIPTLASSNLYKPIFCQQVVEIFNHITRSVAYMDREPQLTAIRECVVQLFTCPTNAKNIFENQSFLDIVWSIIDIFKEFCKVEGGVLIWQRVQKSNLTKSYSISFKQGLYTVETLLSKVHDPNIPLRPKE-IISLLTLCKLFNGAWKIKRKEGEHVLHE---DQNFISYLEYTTSIYSIIQTAEKVSEKSKDSIDSKLFLNAIRIISSFLGNRSLTYK---------------------------LIYDSHEVIKFSVSHERVAFMNPLQTMLSFLIEKVSLKDAYEALEDCSDFLKISDFS-------------LRSVVLCSQIDVGFWVRNGMSVLHQASYYKNNPELGSYSRDIHLNQLAILWERDDIPRIIYNILDRWELLDWFTG----EVDYQHTVYEDKISFIIQQFIAFIYQILTERQYFKTFSSLKDRRMDQIKNSIIYNLYMKPLSYSKLLRSVPDYLT-EDTTEFDEALEEVSVFVEPKGLADNGVFKLKASLYAKVDPLKLLNLENEFESSATIIKSHLAKDKDEIAKVVLIPQVSIKQLDKDALNLGAFTRNTVFAKVVYKLLQVCLDMEDSTFLNELLHLVHGIFRDDELINGKDSIPEAYLSKPICN---------------LLLSIANAKSDVFSESIVRKADYLLEKMIMKKPNELFESLIASFGNQ----YVNDYKD---KKLRQGVNLQETEKERKRRLAKKHQARLLAKFNNQQTKFMKEHESEFDEQDNDVDMVGEKV----------------YESEDFTCALCQDS------SSTDFFVIPAYHDHSPIFRPGNIFNPNEFMPMWDGFYND--DEKQAYIDDDVLEALKENGSCGSRKVFVSCNHHIHHNCFKRYVQKKRFSSNAFICPLCQTFSNCTLPLCQTSKANTGLSLDMFLESELSLDTLSRLFKPFTEENYRTINSIFSLMISQCQGFDKAVRKRANFSHKDVSLILSVHWANTISMLEIASRLEKPYSISFFRSR-EQKYKTLKNILVCIMLFTFVIGKPSMEFEPYPQQPDTVWNQNQLFQYIVRSALFSPVSLRQTVTEALTTFSRQFLRDFLQGLSDAEQVTKLYAK--ASKIGDVLKVSEQMLFALRTISDVRMEGLDSESIIYDLAYTFLLKSLLPTIRRCLVFIKVLHELVKDSENETLVINGHEVEEELEFEDTAEFVNKALKMITEKESLVDLLTTQESIVSHPYLENIPYEYCGIIKLIDLSKYLNTYVTQSKEIKLREERSQHMKNADN--RLDFKICLTCGVKVHLRADRHEMTKHLNKNCFKPFGAFLMPNSSEVCLHLTQPPSNIFISAPYLNSHGEVGRNAMRRGDLTTLNLKR---YEHLNRLWINNEIPGYISRVMGDEFRVTILSNGFLFAFNREPRPRRIPPTDEDDEDMEEGEDGFFTEGNDEMDVDDETGQAANLFGVGAEGIAGGGVRDFFQFFENFRNTLQP---QGNGDDDAPQNPPPILQFLGPQFDGATIIRNTNPRNLDEDDSDDNDDSDEREIW---", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "Q07963-1", "uniprot_id": "UBR2_YEAST", "id": "Q07963-1", "name": "E3 ubiquitin-protein ligase UBR2", "aln": "--MEDSDLSITNIRDFLTELPKLAKCEYSETTSYLLWKTLNLRLKHSDNDINWRSLVSILNSEAWE-------------NEKYRDILNGRKWRTLEFENDHHSVGNMHIG----------TACTRLCFPSETIYYCFTCSTNPLYEICELCFDKEKHVNHSYVAKVVMRPEGRICHCGDPFAFNDPSDAFKCKNELNN--------IPISNDNSNVTDDENVISLLNYVLDFLIDVTVSYKEEAEAHSSERKASSLMHPNQNSITDDIMEKHECEPLVNDENFVFFDNN-------------WSNTRKEAHMEWAIQIEEEECNVHYMDLASTITRILNTPVEYAISITKALEDSHDVVTVLQSENFFEIDQIAKEFQKENIVVHVRKADDIFKRKLTDDLTDWLYS---LCFKAATSLQNKYALRISMLDVWYSHFSKMRVSPTNTNPDFSKINLLGGFLISNEDSDESWFKPWSLENIEDERISKILTNYNERLIRAHSPNTVSHFYNFYGSRFQYIIINSINILSKKSKFKMLKIMASLFSLRDESRKFLAAQYIDVYLSVLYDAVASDAKECQVTLMSILGQYTFQDPSIANMTISSGFIERTIRFAFTLMAFNPEDLMSYLPISLYNGFKLPTETIRNRRTIICFKDLCTIMSANTVPEELLSNEAIFNAIIESFSEFSNVLPLKRETKEHVEVENFDFSAFYFFFSSILIMTDGYTRSISLVKDAAFRKQIVLKLLDVAQTREFESLTNSRKAISPDNASTNENDSNKATLSTVRETICNYVAETINFQVGVNTQYFFNPMSYLFKFVIQWSQCGRYEPIPASLTNYINLFEVFQDKQKALYISESALSTLVLIGQINVGFWVRNGTPITHQARMYTK-YSMREFTYISDIFNVQFSMAMCNPDELMVTYLSRWGLKHWANG----VPMYDYPDTETTVAVVNECILLLIQLLTEVR--SLVMKSSKEGFERTFKSEIIHALCFDTCSYAQIVNCIPEHIT--KHPSFDIYLEKYANYTSPVSLTDNGIFVLKEKYKDEIDPYYIGLSSSRRYDVEKNIRLNMANLKKMKYEDTFVPAKKVKDLLKNTLFSG--LYSISSVNTFGLFLKNTLDHIIKYDYDNLLPRVVHLIHLCVVNNLNEFMGILWHEYAIVD---------------TEFCHYHSIGSILYYCLLKDNFSESHGKIREIFRYLMETAPHVNVNSYLREQTTSYTPGILWPTKEDKSHKDKEFERKKHLARLRKKKLMKKLAQQQMKFMENNSVDTSDISTPRTTSPSLSP----------TRINAENSSNTINSCCDDDCVFCKMPKDDDVFVYFSYQERNICDHGIDFTNPTDVNRINSLFSGKQTKDSAIQENPQDDDGTRLKFTSCEPVLRACGHGSHTKCLSGHMKSIRGIQNQTTKNIPLSYG----SGLIYCPVCNSLSNSFLPKTN-----------DIDKRTSSQFFMCIEKRSEAEENLDPMSSICIKAAMILG-----------DLQGKKVTTIEDAYKVVN-------------SVFINTIS------NTELRLRSHKKEGKIVNMERISSQCILT---LHLVCELKSFIYKKFVNSKTFSSEISRKIWNWNEFLIKG------NNVNLLLYMSQNFDNIDGGKTPQPPNLCIYEMFKRRFHQLLLLLARDMMRVNFYKD---------CRNKIKISSNGSEEPSTSFSYLFNTFKKYVDLFKPDD--------------------------VRFDFTSLEKIKDFICSLLLES--------------------LSIFCRRTFLLFNIQYDDDGDGDNNNNRSNNFMDVKQREIELIFRYFKLPNLTHFLKDFFYNELTQNIERYNDGNDNLRIQQVIYD-----MVQNINTRAYPSPEHIQLIELPLNLSKFSLDNDEISNKCDKYEIAVCLLCGQKCHIQKSIALQGYLQGECTDHMRNGCEITSAYGVFLMTG-TNAIYLSYGKRGTFYAAPYLSKYGETNEDYKFGTPVYLNRARYANLANEIVFGNMIPHIVFRLTDGSADLG-GWETM", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : * :. : . .: . :: * : .*. * * *. : :* ** . * * : . *.*** *::. *: . . .. .. : : : : ::* : : :: : . : :. :: . . : .: :: : : : . . :: * : .:: . : : ::. . : : . * . :: * . : ..:: : . . : . : : : :. : : : * * : : . . . : : : : :. : : *:. :: : .. * .: .*: .*:* *** .: :* * : .: : : .:: *.*: : : : :: : :: .*: * : . ::::: ..:*: . :: :: : : .* ..*:: *: .: : . : . . : : * : : .:: :: :. * * :: : . . : . . : : . * :.: .:* :: ::: :: : * *:..: : . . : . :. : . : : : . .*.* * * :. . . . . ** .: :. . : : : :. .. . : :.. .: : . . . :: : : .: . * : : . . . : . . : :: : . : : . . . :. . : . . : . .: . . *: : . : : : . . * ", "identical_positions": 57, "similar_positions": 306, "identity": "2.75%" }, { "cls_id": "homologset.agr.MGI:1861100", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D4A7F0-1", "uniprot_id": "D4A7F0_RAT", "id": "D4A7F0-1", "name": "E3 ubiquitin-protein ligase", "aln": "---------------------------------------------------------------------------------------------------MAAAAAAAVGGPQPPQPEVSAQGPTLDKAATAAHLKAALSRPDNRAGAEELQALLERVLNAERPLARAAGGE------EAAGGGS--PGEAEEDALEWCKCLLAGGGGYDEFCAAVRAYDPAALCGLVWTANFVAYRCRTCGISPCMSLCAECFHQGDHTGHDFNMFRSQAGGACDCGDSNVMRESGFCRRHQIKSSSNIPCVPKDLLMMSEFVLPRFIFCLIQYLREGYNEPAADTPSEKDLNKVLQLLEPQISFLEDLTKTGGAMRAVLTQVLTNQQSYKDLTAGLGENTCAKKSHEKYLIALKSSGLTYPEDKLVYG--IQEPSAGTSTLAAQGFAGATGTLGQIDSSDEEDQDGSQGLGKRKRVKLSSGTKDQSIMDVLKHKSFLEELLFWTIKYEFPQKMVTFLLNMLPDQEYKVAFTKTFVQHYAFIMKTLKKSHESDTMSNRIVHISVQLFSNEELARQVTEECQLLDIMVTVLLYMMESCLIKSELQDEENSLHVVVNCGEALLKNNTYWPLVSDFINILSHQSVAKRFLEDHGLLVTWMNFVSFFQGMNLNKRELNEHVEFESQTYYAAFAAELEACAQPMWGLLSHCKVRETQEYTRNVVRYCLEALQDWFDAINFVDE----PAPNQVTFHLPLHRYYAMFLSKAVKCQELDLDSLLPDQ-EMLMKLMIHPLQIQASLAEIHSNMWVRNGLQIKGQAMTYVQSHFCNSMIDPDIYLLQVCASRLDPDYFISSVFERFKVVDLLTMASQHHNMVLDVEHERSMLEGALTFLVILLSLRLHLGMSDDEILRAEMVAQLCMNDRTHSSLLDLIPENPNPKSGIIPGSYSFESVLSAVADFKAPVFEPGGSMQQGMYTPKAEVWDQEFDPVMVILRTVYRRDVQSAMDRYTAFLKQSGKFS--GNPWPPYKKRTSLHP--SYKGLMRLLHCKTLHIVLFTLLYKILMDHQNLSEHVLCMVLYLIELGLEDSAEDDS------------EEEVSMGGPERCHDS----------WFPGSNLVSNMRHFINYVRVRVP----------------------ETAPELKR--------DSLASTSSDGLGSLQNSGTAQVFSLVAERRK--------------KFQEIINRNNSE-------------------------------------------------------------ANQVVRPK-TPSKWSAPGSAPQ-------------------------------------------------------------------LTTAILEIKESILSLLIKLHHKLSGKQNSYYPP----------------------WLDDIEVLIQPEIPKYSH------------GDGITAVERILLKAAVQSRMNKRIIEEICRKVTPPVPPKKITTAEKKTLDKEERRQKARERQQKLLAEFASRQKSFMETAMDVDSPENDIPMEITTA---EPQVSEAVYDCVICGQSGPSSEDRPTGLVVLLQASSVLGQCRDNVEPKKLPITEEEQ--IYPWDTCAAVHDVRLSLLQRYFKDSSCLLAVSIGWEGGVYVQTCGHTLHIDCHKSYMESLRNDQVLQGFSVDKGEFTCPLCRQFANSVLPCYPGSNVENNLWQRPSNKSTQDLIKEVEELQGRPGAFPS------------ETNLSKEMESVMKDIKNTTQKKYRDYSKTPGSPDNDFLFMYSVARTNLELELIHRGGSLCSGGAS-TAGKRSCLNQLFHVLALHMRLYTIDSEYNPWKKLTHLVEDMNSQVGSEDQQPEVPVLYHDVTSLLLIQILMMPQPLQKEHFTCIVKVLFTLLYTQALAALSVKGTEEDR-------------------------------SAWKHLGALKKDTCDAEKSYEVLLG----------------------FVISELSKGKLYCEEGAQECTMVSPIAWSPESMERYIQDFCLPFLRISSLLQHHLFGEDLPSCQEE-EEFSVLASCLGLLPTFYQTDHPFISASCLDWPVAAFDIITQWCFEIRSFTERHAEQGKALLI-QESRWKLPHLLQLPENYNTIFQYYHRKTCSVCTKVPKDPAVCLVCGAFVCLKGLCCKQQSYCECVLHSQNCGAGTGIFLLINASVIIIIRGHRFCLWGSVYLDAHGEEDRDLRRGKPLYICEERYRVLEQQWVSHTFDHINKRWGPHYNGL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q5U430-1", "uniprot_id": "UBR3_MOUSE", "id": "Q5U430-1", "name": "E3 ubiquitin-protein ligase UBR3", "aln": "--------------------------------------------------------------------------------------------------MAAAAAAAAVGDPQPPQPEAPAQGLALDKAATAAHLKAALSRPDNRAGAEELQALLERVLNAERPLAGAAGGE------EAAGGGGGGPGEAEEDALEWCKCLLAGGGGYEEFCAAVRAYDPAALCGLVWTANFVAYRCRTCGISPCMSLCAECFHQGDHTGHDFNMFRSQAGGACDCGDSNVMRESGFCRRHQIKSSSNIPCVPKDLLMMSEFVLPRFIFCLIQYLREGYNEPAADAPSEKDLNKVLQLLEPQISFLEDLTKMGGAMRSVLTQVLTNQQNYKDLTAGLGENACAKKSHEKYLIALKSSGLTYPEDKLVYG--VQEPAAGTSTLAAQGFAGATGTLGQIDSSDEEDQDGSQGLGKRKRVKLSSGTKDQSIMDVLKHKSFLEELLFWTIKYEFPQKMVTFLLNMLPDQEYKVAFTKTFVQHYAFIMKTLKKSHESDTMSNRIVHISVQLFSNEELARQVTEECQLLDIMVTVLLYMMESCLIKSELQDEENSLHVVVNCGEALLKNNTYWPLVSDFINILSHQSVAQRFLEDHGLLVTWMNFVSFFQGMNLNKRELNEHVEFESQTYYAAFAAELEACAQPMWGLLSHCKVRETQEYTRNVVRYCLEALQDWFDAINFVDE----PAPNQVTFHLPLHRYYAMFLSKAVKCQELDLDSLLPDQ-EMLMKLMIHPLQIQASLAEIHSNMWVRNGLQIKGQAMTYVQSHFCNSMIDPDIYLLQVCASRLDPDYFISSVFERFKVVDLLTMASQHHNMVLDVEHERSMLEGALTFLVILLSLRLHLGMSDDDILRAEMVAQLCMNDRTHSSLLDLIPENPNPKSGIIPGSYSFESVLSAVADFRAPIFEPGGSMQQGMYTPKAEVWDQEFDPVMVILRTVYRRDVQSAMDRYTAFLKQSGKFP--GNPWPPYKKRTSLHP--SYKGLMRLLHCKTLHIVLFTLLYKILMDHQNLSEHVLCMVLYLIELGLENSADDDS------------EEEVSMGGPERCHDS----------WFPGSNLVSNMRHFINYVRVRVP----------------------ETAPELKR--------DPLASTSSDALDSLQNSGTAQVFSLVAERRK--------------KFQEIINRSNSE-------------------------------------------------------------ANQVVRPK-IPSKWSAPGSSPQ-------------------------------------------------------------------LTTAILEIKESILSLLIKLHHKLSGKQNSYYPP----------------------WLDDIEVLIQPEIPKYNH------------GDGITAVERILLKAAVQSRMNKRIIEEICRKVTPPVPPKKITAAEKKTLDKEERRQKARERQQKLLAEFASRQKSFMETAMDVDSPENDIPMEITTA---EPQVSEAVYDCVICGQSGPSSEDRPTGLVVLLQASSVLGQCRDNAEPKKLPIAEEEQ--IYPWDTCAAVHDVRLSLLQRYFKDSSCLLAVSIGWEGGVYVQTCGHTLHIDCHKSYMESLRNDQVLQGFSVDKGEFTCPLCRQFANSVLPCYPGSNVENNLWQRPCNKSTQDLIKEVEELQGRPGAFPS------------ETNLSKEMESVMKDIKNTTQKKYRDYSKTPGSPDNEFLFMYSVARTNLELELIHRGGSLCSGGPS-TAGKRSCLNQLFHVLALHMRLYTIDSEYNPWKKLTQLVEDMNSQVGNEDQQPEVPILYHDVTSLLLIQILMMPQPLRKEHFTCIVKVLFTLLYTQALAALSVKGTEEDR-------------------------------SAWKHAGALRKDTCDAEKCYEVLLS----------------------FVISELSKGKLYYEEGAQECAMVSPIAWSPESMERYIQDFCLPFLRVSSLLQHHLFGEDLPSCQEE-EEFSVLASCLGLLPTFYQTDHPFISASCLDWPVAAFDIITQWCFEITSFTERHAEQGKALLI-QESRWKLPHLLQLPENYNTIFQYYHRKTCSVCTKVPKDPAVCLVCGTFVCLKGLCCKQQSYCECVLHSQNCGAGTGIFLLINASVIIIIRGHRFCLWGSVYLDAHGEEDRDLRRGKPLYICEERYRVLEQQWVSHTFDHINKRWGPHYNGL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6ZT12-1", "uniprot_id": "UBR3_HUMAN", "id": "Q6ZT12-1", "name": "E3 ubiquitin-protein ligase UBR3", "aln": "---------------------------------------------------------------------------------------------------MAAAAAAAVGGQQPSQPELPAPGLALDKAATAAHLKAALSRPDNRAGAEELQALLERVLSAERPLAAAAGGED-----AAAAGGGGGPGAAEEEALEWCKCLLAGGGGYDEFCAAVRAYDPAALCGLVWTANFVAYRCRTCGISPCMSLCAECFHQGDHTGHDFNMFRSQAGGACDCGDSNVMRESGFCKRHQIKSSSNIPCVPKDLLMMSEFVLPRFIFCLIQYLREGYNEPAADGPSEKDLNKVLQLLEPQISFLEDLTKMGGAMRSVLTQVLTNQQNYKDLTSGLGENACVKKSHEKYLIALKSSGLTYPEDKLVYG--VQEPSAGTSSLAVQGFIGATGTLGQVDSSDEDDQDGSQGLGKRKRVKLSSGTKDQSIMDVLKHKSFLEELLFWTIKYEFPQKMVTFLLNMLPDQEYKVAFTKTFVQHYAFIMKTLKKSHESDTMSNRIVHISVQLFSNEELARQVTEECQLLDIMVTVLLYMMESCLIKSELQDEENSLHVVVNCGEALLKNNTYWPLVSDFINILSHQSVAKRFLEDHGLLVTWMNFVSFFQGMNLNKRELNEHVEFESQTYYAAFAAELEACAQPMWGLLSHCKVRETQEYTRNVVRYCLEALQDWFDAINFVDE----PAPNQVTFHLPLHRYYAMFLSKAVKCQELDLDSVLPDQ-EMLMKLMIHPLQIQASLAEIHSNMWVRNGLQIKGQAMTYVQSHFCNSMIDPDIYLLQVCASRLDPDYFISSVFERFKVVDLLTMASQHQNTVLDAEHERSMLEGALTFLVILLSLRLHLGMSDDEILRAEMVAQLCMNDRTHSSLLDLIPENPNPKSGIIPGSYSFESVLSAVADFKAPVFEPGGSMQQGMYTPKAEVWDQEFDPVMVILRTVYRRDVQSAMDRYTAFLKQSGKFP--GNPWPPYKKRTSLHP--SYKGLMRLLHCKTLHIVLFTLLYKILMDHQNLSEHVLCMVLYLIELGLENSAEEES------------DEEASVGGPERCHDS----------WFPGSNLVSNMRHFINYVRVRVP----------------------ETAPEVKR--------DSPASTSSDNLGSLQNSGTAQVFSLVAERRK--------------KFQEIINRSSSE-------------------------------------------------------------ANQVVRPK-TSSKWSAPGSAPQ-------------------------------------------------------------------LTTAILEIKESILSLLIKLHHKLSGKQNSYYPP----------------------WLDDIEILIQPEIPKYSH------------GDGITAVERILLKAASQSRMNKRIIEEICRKVTPPVPPKKVTAAEKKTLDKEERRQKARERQQKLLAEFASRQKSFMETAMDVDSPENDIPMEITTA---EPQVSEAVYDCVICGQSGPSSEDRPTGLVVLLQASSVLGQCRDNVEPKKLPISEEEQ--IYPWDTCAAVHDVRLSLLQRYFKDSSCLLAVSIGWEGGVYVQTCGHTLHIDCHKSYMESLRNDQVLQGFSVDKGEFTCPLCRQFANSVLPCYPGSNVENNPWQRPSNKSIQDLIKEVEELQGRPGAFPS------------ETNLSKEMESVMKDIKNTTQKKYRDYSKTPGSPDNDFLFMYSVARTNLELELIHRGGNLCSGGAS-TAGKRSCLNQLFHVLALHMRLYSIDSEYNPWRKLTQL-EEMNPQLGYEEQQPEVPILYHDVTSLLLIQILMMPQPLRKDHFTCIVKVLFTLLYTQALAALSVKCSEEDR-------------------------------SAWKHAGALKKSTCDAEKSYEVLLS----------------------FVISELFKGKLYHEEGTQECAMVNPIAWSPESMEKCLQDFCLPFLRITSLLQHHLFGEDLPSCQEE-EEFSVLASCLGLLPTFYQTEHPFISASCLDWPVPAFDIITQWCFEIKSFTERHAEQGKALLI-QESKWKLPHLLQLPENYNTIFQYYHRKTCSVCTKVPKDPAVCLVCGTFVCLKGLCCKQQSYCECVLHSQNCGAGTGIFLLINASVIIIIRGHRFCLWGSVYLDAHGEEDRDLRRGKPLYICKERYKVLEQQWISHTFDHINKRWGPHYNGL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F1QJX5-1", "uniprot_id": "UBR3_DANRE", "id": "F1QJX5-1", "name": "E3 ubiquitin-protein ligase ubr3", "aln": "--------------------------------------------------------------------------------------------------------------------MMAASLLRRDKKSTAAHLKADLKRTDNSSGLRQLQELLDSVLNPER--------------------------GSDPEALDWCKWLLAGGDGFDEFCRTVRSYDNATLCGLVWTANFVAYRCRTCGISPCMSLCAECFNNGDHTGHDFNMFRSQAGGACDCGDGNVMRESGFCNRHRLKTGENVPSVPRDLLLMSEMVLPRFIITIIQYLRDGYTEPES--AADRDLQKVLQQLDPHISFLEELTKMGGAMRTVLTKILTDQQTFKELSMGQEDNVYAKKNYEKYLSALKSSGLVSVEEKGAAGGAGDGTSDAAAGAGALSLLGATATASLDDSSKEEDQDGLQGVGQRKRVKLSSSTKDPSIMDTLKHKCFLEELLFWTIKYEFPQKMVTFLLNMLPDQDYKITFTKTFVQHYAFIMKTLMKSHESDTMSNRIVHISVQLFSNEELARHVTEECQLLDIMVTVLLYMMESCLIKSELQDEENNRHVVVNCGEALLKNNTYWPLVSDFINILSHQSVAKRFLEDHSLLLLWMSFVSFFQGMNLNKRELNEHVEFESQTYYAAFAAELEACAQPMWGLLTHCKVKETQDYTKTVVRYCLETLQMWFDAIGFVDE----PSLNQLTFHLPLHRYYAMFLSKGVKCQGLDLDSLLPDQ-EMLMKIMVHPLQIQASLSEIHSNMWVRNGLQIKGQAMTYVQSHFCNSMIDPDIYLLQVCASRLDPDYFISSVFERFKVVDLLTMASQHQNAVLDSEQERPMLEGALTFLVILCSLRIHLGMSDDEILRAEMVSQLCMNDRTHSSLLDLIPENPNPKSGVVPGSCSFEEMLSGVADFKAPVFEPGGSMQQGMYTPKAEVWEKEFDPIMVILRTVYRRDVQSAMDRYSAFLKQSGVHT--GNPWPPYKERTPLHP--CYKGLVRLLHCKTLHIVIFTLLYKIWMDHQNMSEHVLCMVLYLIELGLDNQVQDDK------------VEEEPC-IEEHCHDS----------WFPGTSLLSNLHHVINFVRVRVP----------------------ETAPEVERKRERERERETPPSTSSESATFGQNLREAQVFSLVAERRR--------------KFQEIINRSNHE-------------------------------------------------------------ASQAVRPKSSASRWLPPGTPPQ-------------------------------------------------------------------LVTEILEIRESMLSLLVKLHQKLSAKQNSLSLS----------------------WLAEVDP------AHHAH------------GDGLTAIERILAKASARSRHSKRCLQEICGKVCPPIPPKKISPGDKKSMDKEERRQRARERQQKLLAEFASRQKSFMETAMDVESPEADAVMDVSSE---ESLDSEVLYDCVICGQSGPSTEDRPTGLVVLLQASSVLGHRCRSDMPKRLPTTDEEH--IYPEDTCGATHDVRLSLMQRYFKDSSCLQSVSIGWDGGVYVQTCGHTLHIDCHKSYMESLRNDQVLQGISVDKGEFTCPLCRQFANSVLPCRPGRGMETGAWHAPSTKSMSTLVKEVEDLQEQLGIFPVRASIKQRDPILIESNLSKEMESVIKDIKNTTQKKYMDYGKNPGSPDNDFLFMYSVARTNLELELVHRGGNLCSGGAS-AAAKRSCLNQLFHVLAMHMRLYSIDSAYNPWTRLTLSTQSRENEYCDEER-PEVPMLFRDVPSLLIIFILTMPQPLRKEHFTCVVKVLYSLQFTQALAALSIRFSREER-------------------------------LAWSNTGAAKKNLPNSDKSWESLLG----------------------HMISELTKAKDVYDTNSEETSALSSSVWSPQSIEFRLQQFCLPFLRLSCLLQHHLYGDSLPGCLVE-EEFSLLTRCLGLAAS-VQCSGSMSSAACLEWNISAFDLISQWCSEVVALSDTPSQQSASLLG-QDPQWAAPRLLQLPDNYNTIFQYYHRKSCSSCGKTPKDPALCLVCGAFVCLKGHCCKQQGVCECVLHSQHCGAATGIFLLINASVIIIIRGHRFCLWGSVYLDAHGEEDRDLRRGKPLYLCEERYRVLEQQWVAHTFDHINKRWGPHYNGL", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9W3M3-1", "uniprot_id": "UBR3_DROME", "id": "Q9W3M3-1", "name": "E3 ubiquitin-protein ligase Ubr3", "aln": "MDEDDNLSNADISIDDEEVVREQTHHPPMQEDQELDNEDGSSDVDLSSVYVVPPIVSAPSPASVRIAGGSTIGGGGVAAGAVPTTTDNSHSPFHDWDSSVAAAAAPPPPPPRTGPTTTTSSGTAAESGAASALSDDAGAKPSFFFGASSFSLRSRKEVAALINTECCRGSPTPDLDSIMDTLFNPGTPIDNLDNIEWIRWLIAGGRTPQEFVKIVRSYDNHAKCGLVWVPHVVAYRCRTCGISPCMSICRDCFKKGNHTNHDFNMFLSQAGGACDCGDTSVMKAEGFCSDHGINNRVNRDPVPNNLLAVAEAIMPKLLFRLLQHFREHSDTPLEVQAITS------YSCEEFANMLIDLNNMGEIMRKVMTRTLIN----PEVYAFFMEAPCQDTRNGRFLKANREK-----------------------------YEDAVNRFPNPEPPDE--YRDLPALG-----------------DKLVHTTLLEEFIFWTFKFEFPQTLVCFLLNMLPDQDYKEHLTRTFVMHYSRIPSVLEMSRDPDTLSNRVVHMSVQLFSNESLALKMVNELSLLHVMIISLKLMMSKILIQNTLHDPNKNFHFVIDCTRQVMKDHCYWPLVSDFNNVLSHESVALVFLRDDNLIDMWFQFLQMLQGMNVNVRETASHVEFEPNSYYAAFSCELEASAYPMWSIISHLQDGTHAHLAKKIINYCVTTLHEWLDSIYFMEARLSMEEMMQASFHFPLHRYLAAFVCQAVTKMGISLNDVLPSRPYLLPLLMIHPLRVQSFFYEILAGKWVRNGLQIKGQAMTYIQANFCNSMADMDLFFLQICATNLPQYFFLQNTIELFDVGQWLETAPLKQ---PQKAEQSSMLEGFLTFLATLVTSRTNLGNDEATQCIIEISALLATENKTHSQLLELMPE----RSGNVH-TKNFETFLKKLSVYKAPSSGSE-NLEQGLFTPIDEVWEKHYDPLHVLLRAVHRRDFQSSLDRFTNYVKSKDKMPASGNLWPPFRLPHALPATSSFSDPCKILNSRIFHSTILSIFFRAVHTRD-VSEHLLALAVFLLEIAVETSDDVGSGTGDRAPPALAAVVESSSGPGYHGYGTGRHEPPKLFHCYPTDNLSCNLRHVVKKVSLKSRDPQVITSSYRSNPFYSDLDFEVEADPEQSMRMIGQGDPEGDEATGGAGLGMGAHSRRNVSQALVPMRVPGMEVALPPDLSVVAETGVVIRQDSNEDDLLREGNHAMDMSPPAALDFHFPLQQITLPESGMEVAIRRDLLLAETNNMGAIAGGAGGGANASATPPAGASNEMFSPTTPTGSGMLLPFQRVQPVAVPSSGNMDIVPSNAMGAGGSFTSGVSGSGTGRRMNYETGGARKRSVDIAIGGSNKDELHLDESILSLLLKLHSQLSGTLDSFSLSDGEDQSSDDDSTMDVDCNEASTSMAAAESTALAERGRSKRNYKNIHVSSSRIGDGPFFIGNLLRKIAKQDEQCAQSIDDIRARLWPNQREKQAEAKAREAKEKEERRKKARERQQKMMQDFANKQKLFMQSAAASSSGMGYGPEDEDDEELYEEQPREKEYDCIICNCTTPSTESNPIGLVVLVESSGIVGHRRRIAERLPLPINAEDESRLAHTTRLAAEFNRRTELLSLKFGDESWYLSNNMAYDNGVHVQSCGHHVHLSCLEAYLKTLYTTQRQP--VQDRGEFYCPVCRQLSNSVLPLSPQLDRPTHLVRS-GNQPFERLVADLTDLIKENETIPQ------------PTKLTEAMGHAMEVMTNIAQRKVKCSSITFR---KLFIFVTSIARTNLEAEIIQRGGSLCTANATRYKPKRECIVPLLHVLSVHVRVLVEWPLWSSWASLAGLPVTATEPLP-AHCLELIPSILADPIALLLKFILLAPLQLDQDYFTCMVKVMYNLLYYQIVVQLCVTLTDLECDHIVKVYGSTSVGSDNSAAESQQQESAAGTTNNRRRAGQQQQSSSQLGKAMALVLSQTNDLVHLRRDCIPSTSSSAAASAAGSSSTTSTNHGASAATASSATTIEVNLKSMELQLQALCLPFLRVAALLRQHLYRHEMPEISAPGLEFVRLVYYLELVTDSMDWDCFNASKGLCFIPGTETTLPQFWCQQLMEVRPPADTVRELVLINQHSLWQQPRLLELPREYERLFTYYHERPCLNCYKVPKESSICLLCGTIVCLKQNCCAENDCCEAVRHTLSCGGGIGIFLVVTSTYIIVIRGRRACLWGSLYLDDFDEEDRDLKRGKPLYLSKDRFNLLESQWLSHKFAHTKHTWVFHRDLL", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .: :. :::* . :.. * .:. : . : : ::* : *:*** :** **:** : *****..:.***************:* :**::*:**.****** *********** .**: .*** * ::. * **.:** ::* ::*:::: ::*::*: * . : .:* :*.: * ** *:*: * : :: : .. ::* * :.. .*. :...* . .:* * * *. :***::***:*:****.:* *********:** :*:*** **: * ..* *::.**:***:**:********.** ::.:* .**.:*: * **.. **:. *:* ::. *.*::* . ::*:: ******** *:***:*** **.*..*: *:.*:.::****:* ** .*****.::*****:.****.* ***.:::* : . ::.::.**: :*: *:*:* *:: * :**:***** * *:.:.*. :.*:.:**.: :* :*:***::*: : ** :. ***************:*::***** * *:::**:**:.* :*:...:* *.* : * *. :: : .: .**** ****. * : * :** .: *: : *. :::***.**:*:** :** : : .** .*. :: ::** . .::**::** ***::.:**: *:**:*:***.**::**:: ::*... . ** ***:: .* . .:.. ::*:.: :* .::::::: :: :***:*.:.::*:*:.:: . : . * . : :.: :* .* .*::*.:: * :: *: ** . : :*.. : :**. * : :*.:.. * *. . * .*. . :.* . *.: **:****:*** :**.. :* . : : : : *** : .:* * : :.. : :::* :: * *: . ::: :*****::*******:: :**.:** **::* .* : * * ***:**. : **:*..* *****:::*.::*: ** *:. : .* .: * .*:. * *.* : .:.::.**:**:*** :*:.* ::*:::* . * *:*** **:***::***** * . . : .:. . *: :: :* . :* ::*:: * .:: :.* :*:* . . : *:*: *:****** *:::***.**:...: **.*: *:***::*:*: . :..* *: . :* : * :**: ** * * :::***:***::.* : * :. *.: : : . * ::. : *. :*. .. . . .: : .. . :*:* :* :******::.**::**: ..:* ** *. * * . : . * . . : ** :: . :* *.. * *:**:** :*: :* ***.:.* * *.**:.::**:**::**** ** ::. **.* *: **.. ****::.:: **:***:* *****:*** ..******:******:.::*:.:**.**::*.* * :: * * : *", "identical_positions": 591, "similar_positions": 592, "identity": "25.63%" }, { "cls_id": "homologset.agr.MGI:1861229", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I6GKX0-1", "uniprot_id": "A0A8I6GKX0_RAT", "id": "A0A8I6GKX0-1", "name": "", "aln": "MDGFIMLGADATALMRVTLLLLWFKGFPSPIDLSQTGSPQYLSSPEVVIPLKVTSGARDAKNSEWLSYSLAFGGRRHVVHMRVKKLLVSTHFSVLTYTEEHAPLSDYPFVPSDCYYHGYVEGAPESLVAFSSCSGGFQGVLQMNGFSYEIEPIKHSSTFEHLVYTLNNNKTQFPPMICNLTEKTLPDQPFGLKEEEKSAVKQN-YRKLWPHTWFLELAVVVDYNFFTYSQQNVSKVRGDVVLVVNMVDSMYKQMDTYVNLVGIEIWNRGNLLPMENIQQVLEDFSHWKQISLSQVHHDAAHIFIRNSLISVLGIAYVAGICRPPLDCGVENFQGDSWSLFANTVAHELGHTFGMRHDEESCSCGEKGCVMSSFRVPAERFTNCSHSDFMKTTLNQGSCLYNHPRPGAGFLVKRCGNGIVESEEECDCGSIRECEQDPCCLFNCTLKPGAACAFGLCCKDCKFMLLGELCRAKINECDLPEWCNGTSHQCPEDGYVQDGVPCGARAYCYQKQCNGHDQQCREVFGKGARSASHNCYKEINSQGTRFGHCGTNGTVYLKCSVSDVLCGKIQCENVEDISHPQAHYAWQNIYASGITCWSTSHCLGMGVPDVGEVKDGTACGIGKICVRKKCVSLSALPNACLPETCNGKGICNNRHHCHCDYGWSLPFCLHRGHGGSIDSGPTSPKRSVDINILTITV--LSVLTCLFIAGLYRTYCLIPSGPKETKS----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9JI76-1", "uniprot_id": "ADA21_MOUSE", "id": "Q9JI76-1", "name": "Disintegrin and metalloproteinase domain-containing protein 21", "aln": "MECFIMLGADARTLMRVTLLLLWLKALPSLIDLSQTGSTQYLSSPEVVIPLKVTSRARGAKNSEWLSYSLVFGGRRHVVHMRVKKLLVSTHIPVLTYTEEHTPLSDYPFVPSDCYYHGYVEGALESLVAFSACNGGLQGVLQMNGFSYEIEPIKHSSTFEHLVYTLNNNKTQFPPMLCSLTEKRLLYQPFGVEEAKKSAMKQN-YGKLWPHMWFLELAVVVDYGFFTNAQQNLSKVRGDVVLVVNMVDSMYKPLDTYVTLVGIEIWNRGNVLPMENIHQVLEDFSHWKQISLSQVHHDAAHIFIRSSLISVLGIAYIAGICRPPLDCGVENFQGDAWSLFANTVAHELGHTFGMKHDEESCSCGKSGCVMSTFRVPAERFTNCSYSDFMKTTLNQGTCLYNHPRPGAGFLVKRCGNGMVESEEECDCGSVQECEQDPCCFLNCTLRPAAACSFGLCCKDCKFMLLGELCRPKINECDLPEWCNGTSHQCPEDGYVQDGVPCGAGAYCYQKQCNNHDQQCREIFGKGARSASHNCYKEINLQGNRFGHCGTDGTVFLKCRMSDVFCGKVHCENVEDIHHPQAPYVLQNIYANGITCWSTGHCLGMGVPDVGEVKDGTTCGVGKICLHKKCVSLSVLSNACLPETCNRKGVCNNKHHCHCDYGWSPPFCLHRGYGGSIDSGPTSQKRRVIITVLSITVPVLSILICLLIAGLYRIYCKIPSGPKETKASSPG", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9UKJ8-1", "uniprot_id": "ADA21_HUMAN", "id": "Q9UKJ8-1", "name": "Disintegrin and metalloproteinase domain-containing protein 21", "aln": "-----MAVDGTLVYIRVTLLLLWLGVFLSISGYCQAGPSQHFTSPEVVIPLKVISRGRSAKAPGWLSYSLRFGGQKHVVHMRVKKLLVSRHLPVFTYTDDRALLEDQLFIPDDCYYHGYVEAAPESLVVFSACFGGFRGVLKISGLTYEIEPIRHSATFEHLVYKINSNETQFPAMRCGLTEKEVARQQLEFEEAENSALEPKSAGDWWTHAWFLELVVVVNHDFFIYSQSNISKVQEDVFLVVNIVDSMYKQLGTYIILIGIEIWNQGNVFPMTSIEQVLNDFSQWKQISLSQLQHDAAHMFIKNSLISILGLAYVAGICRPPIDCGVDNFQGDTWSLFANTVAHELGHTLGMQHDEEFCFCGERGCIMNTFRVPAEKFTNCSYADFMKTTLNQGSCLHNPPRLGEIFMLKRCGNGVVEREEQCDCGSVQQCEQDACCLLNCTLRPGAACAFGLCCKDCKFMPSGELCRQEVNECDLPEWCNGTSHQCPEDRYVQDGIPCSDSAYCYQKRCNNHDQHCREIFGKDAKSASQNCYKEINSQGNRFGHCGINGTTYLKCHISDVFCGRVQCENVRDIPLLQDHFTLQHTHINGVTCWGIDYHLRMNISDIGEVKDGTVCGPGKICIHKKCVSLSVLSHVCLPETCNMKGICNNKHHCHCGYGWSPPYCQHRGYGGSIDSGPASAKRGVFLPLIVIPS--LSVLTFLFTVGLL-MYLRQCSGPKETKAHSSG", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * .: . :********: : * . .*:*..*:::********** * .*.** . ****** ***::************* *:.*:***:::: *.* *:*.*********.* ****.**:* **::***::.*::******:**:*******.:*.*:****.* *.**** : * : .:* ::**:: : . *.* *****.***::.** :*.*:***: **.****:****** :.**: *:******:**::** .*.***:***:********::*****:**:.****:**:**:*******:****:*****:***************:**:**** * **: **:*.:******:*****::**********:**:* ** * *::******:** **:*****:::****.**::****:*.***:*********** ***** ::******************* *****:**. ******:**.***:***:***.*:***:******* **.****** :**.:*** :***:**:::****.** * :. *: : .*:***. .: * *.:.*:*******.** ****::*******.*.:.******* **:***:*****.**** *:* ***:********:* ** * : :: *. **:* *: .** * *******: ", "identical_positions": 461, "similar_positions": 169, "identity": "63.15%" }, { "cls_id": "homologset.agr.MGI:1861231", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9VPS1-1", "uniprot_id": "Q9VPS1_DROME", "id": "Q9VPS1-1", "name": "", "aln": "--------------------------------------------------------------------------------------------------------------------MFKYDTYFLYLIVLLDPQGAQENNCPKVSLSERLEKRGE----FSLVEFDPLLKFIVK--------------NPHKELLGEIEGLVGHTENKLQPMKSVIPNQSKALLNYLD----LHSKLEYLDAAL--------------QKAINSLQCSLKNTKVMS--TGKPHPEFQKLGSRYFYIERHVRQNWFDAADKCRRMGGHLATPQDEDELYLIRKQLEAR------WFWLDISNL---------------VDKDQ-YISLATGKEVSYLKWRHGEPKKS----------------STANCAYLYAGD-----YYTYQCS-DRNFFICQAV-------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VPS2-1", "uniprot_id": "Q9VPS2_DROME", "id": "Q9VPS2-1", "name": "", "aln": "--------------------------------------------------------------------------------------------------------------------MFQHANFFLHVFMACGLYGIRAK-----DVCPRMSTDKE----VCLVELAPVLKYISNNHKSHWNSANEVQVNETRKQLAKIEGQEKETNDKIKVIHDNVDNEFNALSAKIKNVKNIQRHLASLELQL--------------QETKKALNLSVEAKKVMP--KTEIPSQFQKIGWRHFFIEKKHKVDWFKATSMCHKMGAHLLTIQSEDELDAIRTELKDINDG-SHDFWLDINDI---------------AKWGE-FISLATGMNPPFLKWHKHRPQVQ----------------IHQRCVHLRGGE-----MMDGKCS-EQFLFICQLAVN-----------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "D3ZXM6-1", "uniprot_id": "D3ZXM6_RAT", "id": "D3ZXM6-1", "name": "", "aln": "------------------------------------------------------------------------------------------------------------------------------------MVQERHPQ--RKGVCWTLRLWST----AVISMLLLSTCFIAS-------------------CMVTYQFTMEKPNRRLSELHTYHS----------------------------------------------SLTCCSKGTMVSEKLWGCCPNHWKSFGSSCYLISTKENF-WSISEQNYIHMGAHLVVINTETEQNFITQQLNES-----LSYFLGLSDP---------------QGNSK-WQWIDNTPFSQNVRFWHPHEPNL----------------PEEWCASIVYWNPSKWGWNDVFCD-SKHNSICETKKIYL---------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9JKF4-1", "uniprot_id": "CLC6A_MOUSE", "id": "Q9JKF4-1", "name": "C-type lectin domain family 6 member A", "aln": "------------------------------------------------------------------------------------------------------------------------------------MVQERQSQ--GKGVCWTLRLWSA----AVISMLLLSTCFIAS-------------------CVVTYQFIMDQPSRRLYELHTYHS----------------------------------------------SLTCFSEGTMVSEKMWGCCPNHWKSFGSSCYLISTKENF-WSTSEQNCVQMGAHLVVINTEAEQNFITQQLNES-----LSYFLGLSDP---------------QGNGK-WQWIDDTPFSQNVRFWHPHEPNL----------------PEERCVSIVYWNPSKWGWNDVFCD-SKHNSICEMKKIYL---------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6EIG7-1", "uniprot_id": "CLC6A_HUMAN", "id": "Q6EIG7-1", "name": "C-type lectin domain family 6 member A", "aln": "------------------------------------------------------------------------------------------------------------------------------------MMQEQQPQSTEKRGWLSLRLWSV----AGISIALLSACFIVS-------------------CVVTYHFTYGETGKRLSELHSYHS----------------------------------------------SLTCFSEGTKVPA--WGCCPASWKSFGSSCYFISSEEKV-WSKSEQNCVEMGAHLVVFNTEAEQNFIVQQLNES-----FSYFLGLSDP---------------QGNNN-WQWIDKTPYEKNVRFWHLGEPNH----------------SAEQCASIVFWKPTGWGWNDVICE-TRRNSICEMNKIYL---------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VLM0-1", "uniprot_id": "Q9VLM0_DROME", "id": "Q9VLM0-1", "name": "", "aln": "--------------------------------------------------------------------------------------------------------------------MYKYATCIFSIFALWNFWGVSAKKQDTSTGTNELPKAPMPYYTIENIDMHQQHWFTYN-------------SLRQNGTLWRIGNMEQRLEMRLQSFQNQMETKLR--------------------------------------ALKQQIEPYMENVKMSN---KIKMSVFKKIGSRHFYLEKQKKMPWDSAYDTCRQMGGHLANILDEKELNEIFSEETKK------KYWVDINSR---------------ANDGASWISTLSGRDVPFLKWKPNLATN-----------------IHNHCVYINSNE-----MYFENCA-NDNYFACQAEQWA----------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VM16-1", "uniprot_id": "Q9VM16_DROME", "id": "Q9VM16-1", "name": "C-type lectin domain-containing protein", "aln": "--------------------------------------------------------------------------------------------------------------------MFSSTRIILCAFLLLYPYGSLIEAQEGRRYVCLLSDPPNQCSEYCVSALQPVIDHLSKEQQDWG--ACEVKLNGSVAKLDKIEDQLTATQIQIEAQQAFLVNNISKAIKTEDLEQKLKDIEGNQTALSNQLKD---------GQKRTENQLTAIQKTLSDIERKLVLQRYQQIGSRYFYIEHNLQVNWRTAEQRCIEMGGHLAAFQNAEEYNAIVGQLNKAN------YWLGVNDL---------------AKQGE-FISLASGKRATYFKWRKNEPKYNN---------------PTQHCAYVFGHEN---IMIVLSCTTDVMHFICQSDSDV----------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VQU4-1", "uniprot_id": "Q9VQU4_DROME", "id": "Q9VQU4-1", "name": "", "aln": "--------------------------------------------------------------------------------------------------------------------MFRLSVLVLNLLLVSHEFSAGTAKIEIQPLPALCN-------GYCFPTLKPVMEYVAIHQDKWN-TCTEILANEARKDQIQLNIQLDALKADVSNIKASQLSKDEKLDRMEREQFAMHESLETINRYLTVKLDRTKLQLEAIKNTMDYMKAQMDGYFSAINGVQCLQPGFEKIGDRYFYIEEDVELNWLDAQAKCRRMGGHLASIKTKQEFDAIVEKLDDSK-----SYFLGVNEN---------------TKTGD-FVSAASGKSCLYHEWGPGEPHHNN---------------DQERCVSILRKL-----MHVGNCT-YEKRFICQYGI------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "B0S6P2-1", "uniprot_id": "B0S6P2_DANRE", "id": "B0S6P2-1", "name": "", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MMVMLRSLLL-----------------------------------------------LSLFSMGNAAAR----RCTRQWSRFGSRCFRYFS-VPVNWVTAERNCQLLGGNLVSVQNGMENDFLLSLIPNSE-----RFFIGGYDG---------------EDEEN-WFWSE-GSSFGYTNWCSGEPNNM----------------NTEHCLEINWTSDR--CWNNLPCS-TEQGYICAKNLDGCS--------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q59DY5-1", "uniprot_id": "LEDL3_DROME", "id": "Q59DY5-1", "name": "C-type lectin 37Db", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MMVKLLLLFLVCWSALP---------------------------------------------------LESSPLGN-------RYNLEIGEKQYYISLAKTN-WFEASNHCRQNGGFLLNLESREELELLSPHLHPAY-----SYWLSINDL---------------GERGV-YVSEATGLEAPFLNWSAGEPDNSS---------------GYDRCVELWLSTTS-FQMNDLPCY-SSVAFICQLN-------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "A0A8M9PGK7-1", "uniprot_id": "A0A8M9PGK7_DANRE", "id": "A0A8M9PGK7-1", "name": "", "aln": "-----------------------------------------------------------------------------------------------------------------------MGSVYENSVFAFSTGNSDENDSQYKGHFSNYRESKREVNTAKWTKVLLIVFAVSLVFALGGLCAVRIQYVSVSAQLSAQETNGTIMSRQLDKLTANFTTVRDHLHINELLMKELTANYSRVKEQLS----------------ISEETVRKLSRFNQSSGCAICAIHWTHSGEKCYYFST-VKMNWTQSRDHCVTKGGHLVIITSQAEQEFLTSNVKET-------HWIGLNDL---------------DTEGR-WLWVDNQPLSQTEEFWMKRENGVSEPD-----NWTKQHVDGEDCASLGHPDGETDFWTDAYCF-EEKRFVCEAAAAV----------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "B7Z0K3-1", "uniprot_id": "B7Z0K3_DROME", "id": "B7Z0K3-1", "name": "C-type lectin domain-containing protein", "aln": "MPPAGQQLRLTALVYLALGIALLCNGSDGETRQKYANESLADADDPSPVWSQFLEDYVLSQGSSSSGSQRKSKDLPYMGADMGINGPLSYHSSAYKRPGNNIYITRRIGEAVELEPHLRKPVESQSPIVNPQFRPMTNQMLHQQHQQMQQQQQQQQLQQRQQPGFLQQLFGIGGSGGGGGSGTQQQQHVRPVPLQQQQVQQIAQQHPQQQHLVGGQPTTFRAVSENDLYLLGAIEKLVYRVDYLESR-----------VRRSEQLIYYLMAGNNQKEVKDPCPANFTRISDNCYYINSQQQVNWKTANSACKGLNSHLAEFEKVSENEEIMAYLLNQPTHRGRDYWLGGLNPGLLWIWSNSAKPVNPNMNLTSIAMAQKGENSTAANLVDSSEQAAEEATGEDVLNNTVQIEGKGRCLRLSYNAGKHSYVYYGQECTSRHYYICEHEDKTLDNKIKKITRELKLFE", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . : * : .. * * : .::. . . * : * ", "identical_positions": 5, "similar_positions": 13, "identity": "1.07%" }, { "cls_id": "homologset.agr.MGI:1861232", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9VPS1-1", "uniprot_id": "Q9VPS1_DROME", "id": "Q9VPS1-1", "name": "", "aln": "--------------------------------------------------------------------------------------------------------------MFKYDTYFLYLIVLLDPQGAQENNC----PKVSLSERLEKRGEFSLVEFDPLLKFIVK-----------------NPHKELLGEIEGLVGHTENKLQPMKSVIPNQSKALLNYLD----LHSKLEYLDAALQKAINSLQCSLKNTKV----------------MSTGKPHPEFQKLGSRYFYIERHVRQNWFDAADKCRRMGGHLATPQDEDELYLIRKQLEAR------WFWLD----------------ISNLVDKDQYISLATG-KEVSYLKWRHGEPK---------------KSSTANCAYLYAG-----DYYTYQCS-DRNFFICQAV-------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VPS2-1", "uniprot_id": "Q9VPS2_DROME", "id": "Q9VPS2-1", "name": "", "aln": "--------------------------------------------------------------------------------------------------------------MFQHANFFLHVFMACGLYGIRAK---------DVCPRMSTDKEVCLVELAPVLKYISNNHKSHWNS---ANEVQVNETRKQLAKIEGQEKETNDKIKVIHDNVDNEFNALSAKIKNVKNIQRHLASLELQLQETKKALNLSVEAKKV----------------MPKTEIPSQFQKIGWRHFFIEKKHKVDWFKATSMCHKMGAHLLTIQSEDELDAIRTELKDINDG-SHDFWLD----------------INDIAKWGEFISLATG-MNPPFLKWHKHRPQ---------------VQIHQRCVHLRGG-----EMMDGKCS-EQFLFICQLAVN-----------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q67EQ1-1", "uniprot_id": "CLC4E_RAT", "id": "Q67EQ1-1", "name": "C-type lectin domain family 4 member E", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------MNSTKSPASHHTERECFKNSQVLSWTMAG----------------------------------ASILFLSVCFITRCVVTYHSFQ-------IYGQKKLQPHKTIKELSCYLEASGS----------------VKN-CCPLNWKHFQSSCYFFS-TTTLSWLSSLKNCSDMGAHLVVINTWEEQEFLFRTKPRKK-----EFYIG----------------LTDQVVEGQWRWVDDTPFTESLSFWDAGEPNN--------------IVFVEDCATMRDSSNPRKNWNDVSCF-FSMPWICEMPEISPLD-------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9R0Q8-1", "uniprot_id": "CLC4E_MOUSE", "id": "Q9R0Q8-1", "name": "C-type lectin domain family 4 member E", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------MNSTKSPASHHTERGCFKNSQVLSWTIAG----------------------------------ASILFLSGCFITRCVVTYRSSQ-------ISGQN-LQPHRNIKELSCYSEASGS----------------VKN-CCPLNWKHYQSSCYFFS-TTTLTWSSSLKNCSDMGAHLVVIDTQEEQEFLFRTKPKRK-----EFYIG----------------LTDQVVEGQWQWVDDTPFTESLSFWDAGEPNN--------------IVLVEDCATIRDSSNSRKNWNDIPCF-YSMPWICEMPEISPLD-------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9ULY5-1", "uniprot_id": "CLC4E_HUMAN", "id": "Q9ULY5-1", "name": "C-type lectin domain family 4 member E", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------MNSSKSSETQCTERGCFS-SQMFLWTVAG----------------------------------IPILFLSACFITRCVVTFRIFQ-------TCDEKKFQLPENFTELSCYNYGSGS----------------VKN-CCPLNWEYFQSSCYFFS-TDTISWALSLKNCSAMGAHLVVINSQEEQEFLSYKKPKMR-----EFFIG----------------LSDQVVEGQWQWVDGTPLTKSLSFWDVGEPNN--------------IATLEDCATMRDSSNPRQNWNDVTCF-LNYFRICEMVGINPLNKGKSL--------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9PGK7-1", "uniprot_id": "A0A8M9PGK7_DANRE", "id": "A0A8M9PGK7-1", "name": "", "aln": "----------------------------------------------------------------------------------------------------------------MGSVYENSVFAFSTGNSDENDSQ----YKGHFSNYRESKREVNTAKWTKVLLIVFAVSLVFALGGLCAVRIQYVSVSAQLSAQETNGTIMSRQLDKLTANFTTVRDHLHINELLMKELTANYSRVKEQLSISEETVRKLSRFNQS----------------SGCAICAIHWTHSGEKCYYFS-TVKMNWTQSRDHCVTKGGHLVIITSQAEQEFLTSNVKETH-------WIG----------------LNDLDTEGRWLWVDNQPLSQTEEFWMKRENGVSEPD-----NWTKQHVDGEDCASLGHPDGETDFWTDAYCF-EEKRFVCEAAAAV----------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VLM0-1", "uniprot_id": "Q9VLM0_DROME", "id": "Q9VLM0-1", "name": "", "aln": "--------------------------------------------------------------------------------------------------------------MYKYATCIFSIFALWNFWG-------------VSAKKQDTSTGTNELPKAPMPYYTIEN-------------------------------IDMHQQHWFTYNSLRQNGTLWRIGNMEQRLEMRLQSFQNQMETKLRALKQQIEPYMENV-------------KMSNKIKMSVFKKIGSRHFYLEKQKKMPWDSAYDTCRQMGGHLANILDEKELNEIFSEETKKK------YWVD----------------INSRANDGASWISTLSGRDVPFLKWKPNLATN----------------IHNHCVYINSN-----EMYFENCA-NDNYFACQAEQWA----------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VM16-1", "uniprot_id": "Q9VM16_DROME", "id": "Q9VM16-1", "name": "C-type lectin domain-containing protein", "aln": "--------------------------------------------------------------------------------------------------------------MFSSTRIILCAFLLLYPYGSLIEAQEGRRYVCLLSDPPNQCSEYCVSALQPVIDHLSKEQQDWGACEVKLNG--SVAKLDKIEDQLTATQIQIEAQQAFLVNNISKAIKTEDLEQKLKDIEGNQTALSNQLKDGQKRTENQLTAIQKTLS------------DIERKLVLQRYQQIGSRYFYIEHNLQVNWRTAEQRCIEMGGHLAAFQNAEEYNAIVGQLNKAN------YWLG----------------VNDLAKQGEFISLASG-KRATYFKWRKNEPKYN--------------NPTQHCAYVFGHEN---IMIVLSCTTDVMHFICQSDSDV----------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VQU4-1", "uniprot_id": "Q9VQU4_DROME", "id": "Q9VQU4-1", "name": "", "aln": "--------------------------------------------------------------------------------------------------------------MFRLSVLVLNLLLVSHEFSAGTAK-------IEIQPLPALCNGYCFPTLKPVMEYVAIHQDKWNTCTEILAN----EARKDQIQLNIQLDALKADVSNIKASQLSKDEKLDRMEREQFAMHESLETINRYLTVKLDRTKLQLEAIKNTMDYMKAQMDGYFSAINGVQCLQPGFEKIGDRYFYIEEDVELNWLDAQAKCRRMGGHLASIKTKQEFDAIVEKLDDSK-----SYFLG----------------VNENTKTGDFVSAASG-KSCLYHEWGPGEPHHN--------------NDQERCVSILRK-----LMHVGNCT-YEKRFICQYGI------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q59DY5-1", "uniprot_id": "LEDL3_DROME", "id": "Q59DY5-1", "name": "C-type lectin 37Db", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MMVKLLLLFLVCWSALPLESSPLGN-----------------------RYNLEIGEKQYYIS-LAKTNWFEASNHCRQNGGFLLNLESREELELLSPHLHPAYS-----YWLS----------------INDLGERGVYVSEATG-LEAPFLNWSAGEPDNS--------------SGYDRCVELWLSTTS-FQMNDLPCY-SSVAFICQLN-------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "B7Z0K3-1", "uniprot_id": "B7Z0K3_DROME", "id": "B7Z0K3-1", "name": "C-type lectin domain-containing protein", "aln": "MPPAGQQLRLTALVYLALGIALLCNGSDGETRQKYANESLADADDPSPVWSQFLEDYVLSQGSSSSGSQRKSKDLPYMGADMGINGPLSYHSSAYKRPGNNIYITRRIGEAVELEPHLRKPVESQSPIVNPQFRPMTNQMLHQQHQQMQQQQQQQQLQQRQQPGFLQQLFGIGGSGGGGGSGTQQQQHVRPVPLQQQQVQQIAQQHPQQQHLVGGQPTTFRAVSENDLYLLGAIEKLVYRVDYLESRVRRSEQLIYYLMAGNN--------QKEVKDPCPANFTRISDNCYYINSQQQVNWKTANSACKGLNSHLAEFEKVSENEEIMAYLLNQPTHRGRDYWLGGLNPGLLWIWSNSAKPVNPNMNLTSIAMAQKGENSTAANLVDSSEQAAEEATGEDVLNNTVQIEGKGRCLRLSYNAGKHSYVYYGQECTSRHYYICEHEDKTLDNKIKKITRELKLFE", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :::. * : * ...* * : ::. :. * : *: ", "identical_positions": 6, "similar_positions": 16, "identity": "1.3%" }, { "cls_id": "homologset.agr.MGI:1861305", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P49356-1", "uniprot_id": "FNTB_HUMAN", "id": "P49356-1", "name": "Protein farnesyltransferase subunit beta", "aln": "MASPSSFTYYCPPSSSPVWSEPLYSLRPEHARERLQDDS---VETVTSIEQAKVEEKIQEVFSSYKFNHLVPRLVLQ--REKHFHYLKRGLRQ-LTDAYECLDASRPWLCYWILHSLELLD-EPIPQIVATDVCQFLELCQSPEGGFGGGPGQYPHLAPTYAAVNALCIIG-TEEAYDIINREKLLQYLYSLKQPDGSFLMHVGG-EVDVRSAYCAASVASLTNIITP---DLFEGTAEWIARCQNWEGGIGGVPGM-EAHGGYTFCGLAALVILKRERSLNLKSLLQWVTSRQMRFEGGFQGRCNKLVDGCYSFWQAGLLPLLHRALHAQGDPALSMSHWMFHQQALQEYILMCCQ-CPAGGLLDKPGKSRDFYHTCYCLSGLSIAQHFGSGAMLHDVVLGVPENALQPTHPVYNIGPDKVIQATTYFLQKPVPGFEELKDETSAEPATD", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8K2I1-1", "uniprot_id": "FNTB_MOUSE", "id": "Q8K2I1-1", "name": "Protein farnesyltransferase subunit beta", "aln": "MASSSSFTYYCPPSSSPVWSEPLYSLRPEHVRERLQDDS---VETVTSIEQAKVEEKIQEVFSSYKFNHLVPRLILQ--REKHFHYLKRGLRQ-LTDAYECLDASRPWLCYWILHSLELLD-EPIPQIVATDVCQFLELCQSPDGGFGGGPGQYPHLAPTYAAVNALCIIG-TEEAYNVINREKLLQYLYSLKQPDGSFLMHVGG-EVDVRSAYCAASVASLTNIITP---DLFEGTAEWIARCQNWEGGIGGVPGM-EAHGGYTFCGLAALVILKKERSLNLKSLLQWVTSRQMRFEGGFQGRCNKLVDGCYSFWQAGLLPLLHRALHAQGDPALSMSHWMFHQQALQEYILMCCQ-CPAGGLLDKPGKSRDFYHTCYCLSGLSIAQHFGSGAMLHDMVMGVPENVLQPTHPVYNIGPEKVIQATTHFLQKPVPGFEECEDEVTSDPATD", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9VEV7-1", "uniprot_id": "Q9VEV7_DROME", "id": "Q9VEV7-1", "name": "Protein farnesyltransferase subunit beta", "aln": "MGTEEELMFRN--------FQRLKSY-------IFDDEK---VSTTTSREQQKTESSVEKCFDRFEQIMFTDPRLTQIFRLEHQYYLDAMLRR-LPSNYECLDSSRAWCVYWILQAAQLLS-FNFDDQTLNHVVQFLSNCRSPTGGFGGGPGQYAHLAPTYAAVNSLCIIG-SEQAYRAIDRPTLVQFLFSVRDSDGSFRLHVDG-ETDVRGAYCAISCAKLLNLPEPVIKELFAGTGDWIAQCQTYEGGFGGAPGL-EAHGGYTFCGIAGLALLNEADKCDRQALLKWTLRRQMTYEGGFQGRTNKLVDGCYSFWVGATIPITQATLSG---VDKQMEHTLFDVEALQEYILLCCQ-KQSGGLIDKPGKPQDLYHTCYTLSGVSIAQHSECASSPQ--VLGDTINELLPTHPLFNIPPKSVAAARSHFSNSNDTEFLG-KDSPSKEES--", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P22007-1", "uniprot_id": "FNTB_YEAST", "id": "P22007-1", "name": "Protein farnesyltransferase subunit beta", "aln": "MRQRVGRSIARAKFINTALLGRKRPVMERVVDIAHVDSSKAIQPLMKELETDTTEARYKVLQSVLEIYDDEKNIEPALTKEFHKMYLDVAFEISLPPQMTALDASQPWMLYWIANSLKVMDRDWLSDDTKRKIVDKLFTISPSGGPFGGGPGQLSHLASTYAAINALSLCDNIDGCWDRIDRKGIYQWLISLKEPNGGFKTCLEVGEVDTRGIYCALSIATLLNILTE---ELTEGVLNYLKNCQNYEGGFGSCPHVDEAHGGYTFCATASLAILRSMDQINVEKLLEWSSARQLQEERGFCGRSNKLVDGCYSFWVGGSAAILEAFGYG----------QCFNKHALRDYILYCCQEKEQPGLRDKPGAHSDFYHTNYCLLGLAVAESSYSCTPND-----SPHNIKCTPDRLIGSSKLTDVNPVYGLPIENVRKIIHYFKSNLSSPS--", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "A0ABK0L564-1", "uniprot_id": "A0ABK0L564_RAT", "id": "A0ABK0L564-1", "name": "Protein Churchill", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------MCG------DCVEK----------KYPN--------------RGNTCLENGSFLLN------------------------------------FAGCAVCSKRDFMLITN------RSLKEEDGEEIVTYDHLCKNCHHVIARHEYTFSIMDEFQVLQEALKG-------------------GTSPTCCP------------------------CSLPTCRFCSSSALFP-------MRIFWTPSGAY------------------------------------", "tax_id": 10116, "tax_name": "Rat" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . ::: : .: *. * . : * * ..* :.*. : :: . * : . : : . : :. *:* : . . ** .:. .. . : . .. ", "identical_positions": 11, "similar_positions": 42, "identity": "2.44%" }, { "cls_id": "homologset.agr.MGI:1861354", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q7Z5R6-1", "uniprot_id": "AB1IP_HUMAN", "id": "Q7Z5R6-1", "name": "Amyloid beta A4 precursor protein-binding family B member 1-interacting protein", "aln": "--------------------------------------------------------------------------------------------------------------------------------MGESSEDIDQMFSTLLGEMDLLTQSLG----------------VDTLPPPDPNPP----RAEFNYSVGFKDLNESLNALEDQDLDALMADLVAD-----------------------------------ISEAEQRTIQAQKESLQNQHHSASLQASIFSGAASLGYGTNVAATGISQYEDDLPPPPADPVLDLPLPPPPPEP-------LSQEEEEAQAKADKIKLALEKLKEAKVKKLVVKVHMNDNSTKSLMVDERQLARDVLDNLFEKTHCDCNVDWCLYEIYPELQIERFFEDHENVVEVLSDWTRDTENKILFLEKEEKYAVFKNPQNFYLDNRGKKESKETNEKMNAKNKESLLEESFCGTSIIVPELEGALYLKEDGKKSWKRRYFLLRASGIYYVPKGKTKT--SRDLACFIQFENVNIYYGTQHKMKYKAPTDYCFVLKHP---QIQKESQYIKYLCCDDTRTLNQWVMGIRIAKYGKTLYDNYQRAVAKAGLAS-------------RWTNLGTVNAAAPAQP---STGPKTGTTQPNGQIPQATHSVSA------------------------------------------------------VLQEAQRHAETSKDKKPALGNHHDPAVPRAPHAPKSSLPPPPP-VRRSSDTSGSPATPLKAKGTGGGGLPAPPD------------DFLPPPPPPPPLDDPE--------------LPPPPPDFME--------PPPDFVP-------------------------------------PPPPSYAGIAGSELPPPPPPPPAPAPAPVPDSARPPPAVAKRPPVP---------------------------------------------------PKRQENPGHPGGAGGGEQDFMSDLMKALQKKRGNVS---------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8R5A3-1", "uniprot_id": "AB1IP_MOUSE", "id": "Q8R5A3-1", "name": "Amyloid beta A4 precursor protein-binding family B member 1-interacting protein", "aln": "--------------------------------------------------------------------------------------------------------------------------------MGESNEDIDQMFSTLLGEMDLLTQSLG----------------VDTLPPPDPNPP----REEFNYTVGFKDLNESLNALEDQDLDALMADLVAD-----------------------------------ISEAEQRTIQAQKESSQNQDRFALLRASDGQGTASGGYGASAAAIDVSHHEEALPPPPVEPMLDLLPPPPPPPPPEL----LSKEEEEAKAKADKIKLALEKLKEAKVKKLVVKVHMDDSSTKSLMVDERQLARDVLDNLFEKTHCDCNVDWCLYEIYPELQIERVFEDHENVVEVLSDWTRDTENKVLFLEKEERYAVFKNPQNFYLDNKGKKENKETNEKMNAKNKEYLLEESFCGTSIIVPELEGALYLKEDGKKSWKRRYFLLRASGIYYVPKGKTKT--SRDLACFIQFENVNIYYGIQCKMKYKAPTDHCFVLKHP---QIQKESQYIKYLCCDDARTLSQWVMGIRIAKYGKTLYDNYQRAVARAGLAS-------------RWTNLGTVGTPMPAQPSTVSSGLKTGTSQPNGQMPQAIPSAGP------------------------------------------------------PLQEAQTQIETTKDEKQGLGN-HSPGATRENHRPKSSLPPPPPPVRRSSDTCGSPALPSKVKGPGTCTFPHPPE------------NFLPPPPPPPPEEDNSGL-----------LPPPPPPPYLE--------EPPDFVP-------------------------------------PPPPP-AAVEDSALPPPPPPPPCLSQEITKSSPLPP----KKPLVP---------------------------------------------------PKRQENQGLPGAPGNSEQDFMSDLMKALQKKRGNIP---------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6PFT9-1", "uniprot_id": "AB1IP_DANRE", "id": "Q6PFT9-1", "name": "Amyloid beta A4 precursor protein-binding family B member 1-interacting protein", "aln": "------------------------------------------------------------------------------------------------------------------------------------MDDIDAMFSDMLQEMDLLTQSLD----------------AEVDSAPLAKPPTIPEPQEMNFSIGFANFNESLNDLEDNDLDALMADLVAD-----------------------------------ISATEEKFATERDTS---------------KGSVPVAPAPSKPQSNFSLPASFDSSKPATSSNSIAAPPPPPAFK------PSKEEEEEQLKADKIKLALEKLKEAKVKKLVVKVEITDGSSKTLMVDERQTVRDVMDNLFEKTHCDCNVDWSVCETNPDLQTERAFEDHENLVEPLSTWTRDTENKVLFQEKKHKYEVFKNPQIFYLWKKDKKSLKD----MKEKDKEQLLEENFCGASVIVPDLEGVLYLKEDGKKSWKQRYFLLRASGLYYSPKGKTKA--SRDLVCLVQFDNVNVYYCKEYRIKYKAPTDHCFMLKHP---QIQKESQYIKFMCCDDEWSMNLWVTGIRVAKYGKQLYDNYKAAVRKASGSA-------------SWANRTIQASSTASTP-----SPTPKAKAANGHAPQ--PPVEN------------------------------------------------------KVPSNQSSLPPPPPSMDFLPP--PPPDPMFPPPPPAPPAPPAPPVPVSSTKVNKFPPPPKFPQS---SFPPPPM------------DDLPPPPPPPEIADLPPD-----------FLPPPPPSFVSHGGESLPPPPPDPVAS-----------------------------------LPPPPPAFTSAGGAPPPPPPPPPPPAPAPAVNNPAGS---VRKVAPP---------------------------------------------------PPKRTTPQLAAPSGG---DFMSELMNAMQKKRTQP----------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VWB7-1", "uniprot_id": "Q9VWB7_DROME", "id": "Q9VWB7-1", "name": "", "aln": "MDCGGIAAHQQQQLQQQQLHLLQQQLQQQHHQQQRQQQQHSLEEAATITNINLRGILVGGAASSAGVAGAAAGGATTTTTTTTAAGFVAGGDCPVIGAGAGAGVKLRRHSDRPLTPEAKQLSHTYRISMANLEDSQESELDQILGELSLLEAQISYTEASMLPAMCAPSAGAQIAPPPGVTQLPGSAPTMVSMSASSSRSHSRTNSTISADVSSCSSSGISENGHGLGLVLGGPGSAGMMVQPPPPGGMTMGITLGVVTPREPRTESPDNDSAFSDTVSLLSSESSASSNTSLQQQQQQQQQQHHQHQQHHQHQQQQQKPQLAGAEKLHHHGVHGQHGGQQSGANSITKADKIQLALHKLESAPIRRLFVKAFTSDGASKSLLVDERMGCGHVTRLLADKNHVQMQSNWALVEHLGDLQMERLFEDHELLVDNLMTWHSDAGNRVLFQQRPDKVTLFLRPELYLPGPQMAPGCQH-----DEQTRQMLLDEFFD--SHNQLQMDGPLYMKADPKKGWKRYHFVLRSSGLYYFPKEKTKN--TRDLACLNLFHGHNVYTGLGWRKKWKSPTDYTFGFKAVGDSSLGKSCRSLKMLCAEDLPTLDRWLTAIRVCKYGKQLWDSHKSLLEDLCLSRDDAVSQSSFAASMRSESISSISSAVPSQCGSVSSAISSMSNSTSGRTSRASSSSSSGCLSDDNNAFDSEFTTGTIKRKPSMKPNLPLTTMTRQLKEVGEITICESAGGDASSPERSGTLTRRHSRRKSQESNGSGTLKRRPIAVPVATVVKQTEPMGSASSTSSSSNSTPTPTPSICAKPPPGDSASLMCSSTLSLDSLPPPPPPPALDGSEDQDVYGSQLSLASLPPPPPPEDVLAMNYAEPSSPSTPTPMSTPMIMPNSNGSLPPAVPAKPMKPAVKQAAGGLKAAPPYKAPPDYVGPALLPGPPLPPPPPAQKKVSFADSPVLLRRKMCSPEPVLPQRSPSTTLSCHSSSSAGSAYQTYAPGPMLPPRADVARLSSLSNGSSSEVTSPKRLQESASNPPRDFLKDLQRVMRKKWQVAQKCKAEPATTPHEVLGFRDFSNEDLLAAHNLNSGANSSHYYRETANVSHWVRKHYEYAHNALYENVHAQSAAAAGVPGSGEATTPPLPPPPGNSVAAKKRPPPPPPKRSDKTHLTNRV", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q05683-1", "uniprot_id": "DCE2_RAT", "id": "Q05683-1", "name": "Glutamate decarboxylase 2", "aln": "------------------------------------------------------------------------------------------------------------------------------------------MASPGSGFWSFGSEDGS------------------------------GDPENPGTARAWCQVAQKFTGGIGNKLCALLYGDSEK-------------------------------------PAE-------------------------SGGSVTSRAATRKVACTCDQKPCSCPKGDVNYALLHATDLLPACE------------GERPTLAFLQDVMNILLQYVVKSFDRSTKVIDFHYPNELLQEYNWELADQPQNLEEILTHCQTTLKYAIKTGHPRYFNQLSTGLDMVGLAADWLTSTANTNMFTYEIAPVFVLLEYVTLKKMREIIGWPGG-----SGDGIFSPGGAISNMYAMLIARYKMFPEVKEKGMAAVPRLIAFTSEHSHFSLKKGAAALGIGTDSVILIKCDERGKMIPSDLERRILEVKQKGFVPFLVS-----ATAGTTVYGAFDPLLAVADICKKYKIWMHVDAAWGGGLLMSRKHKWKLN-------------GVERANSVTWNPHKMMGVPLQCSALLVREEGLMQSCNQMHAS----------------------------------------------------YLFQQDKHYDLSYDTGDKALQCGRHVDVFKLWLMWRAKGTTGFEAHIDKCLELAEYLYNIIKNREGYEMVFDGKPQHTN--------VCFWFVPPSLRVLEDNEER--------------------------------------------------------------------------------MSRLSKVAPVIKARMMEYGTTMVSYQPLGDKVNFFRMVIS------------------------------------------------------------NPAATHQDIDFLIEEIERLGQDL-------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . .: . . . : . . . . .: : . . * .. : . . :: .:. * . :: : .. * . :::* :: . : . : . :. :* * .: * :* . :: . . . . : . :* . . : . . : * : * . : . . . : .: * . . : :: :: : . :.. . : . .. .* . . . **. . . . . : . . **: : . : :. ", "identical_positions": 17, "similar_positions": 109, "identity": "1.45%" }, { "cls_id": "homologset.agr.MGI:1861376", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9JIP7-1", "uniprot_id": "S15A1_MOUSE", "id": "Q9JIP7-1", "name": "Solute carrier family 15 member 1", "aln": "---------------------------------------------------------------------------------------------------------------------MGMSKSRGCFG---YPLSIFFIVVNEFCERFSYYGMRALLVLYFRN--------FLGWDDNLSTAIYHTFVALCYLTPILGALIADSWLGKFKTIVSLSIVYTIGQAVISVSSINDLTDHDHNGSPDSLPVHVALSMVGLALIALGTGGIKPCVSAFGGDQFEE----------------GQEKQRNRFFSIFYLAINGGSLLSTIITPILRVQQCGIHSQQACYPLAFGVPAALMAVALIVFVLGSGMYKKFQPQG-NIMGKVAKCIGFAIKNRFRHRSKAYPKREHWLDWAKEKYDERLISQIKMVTKVMFLYIPLPMFWALFDQQGSRWTLQATTMNGKIGAIEIQPDQMQTVNAILIVIMVPIVDAVVYPLIAKCG-FNFTSLKKMTVGMFLASMAFVVAAIVQVEIDKT----LPVFPGGNQVQIKVLNIGNNNMTVHFPGNS-VTLAQMS--------------------------QTDTFMTFDIDKLTSINISSSGSPGVTTVAHDFEQGHRHTLLVWNPSQYRVVKDGLNQKPEKGENGIRFVNTLNEMVTIKMSGKVYENVTSHNASGYQFFPSGEKQYTINTTAVAPTCLTDFKSSNLDFGSAYTYVIR-RASDG---CLEVKEFEDIPPNTVNMALQIPQYFLLTCGEVVFSVTGLEFSYSQAPSNMKSVLQAGWLLTVAVGNIIVLIVAGAGHFPKQWAEYILFASLLLVVCVIFAIMARFYTYINPAEIEAQFDE----DEKKKG---IGKENPYSSLEPV----SQTNM------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P51574-1", "uniprot_id": "S15A1_RAT", "id": "P51574-1", "name": "Solute carrier family 15 member 1", "aln": "---------------------------------------------------------------------------------------------------------------------MGMSKSRGCFG---YPLSIFFIVVNEFCERFSYYGMRALLVLYFRN--------FLGWDDDLSTAIYHTFVALCYLTPILGALIADSWLGKFKTIVSLSIVYTIGQAVISVSSINDLTDHDHDGSPNNLPLHVALSMIGLALIALGTGGIKPCVSAFGGDQFEE----------------GQEKQRNRFFSIFYLAINAGSLLSTIITPILRVQQCGIHSQQACYPLAFGVPAALMAVALIVFVLGSGMYKKFQPQG-NIMGKVAKCIRFAIKNRFRHRSKAFPKRNHWLDWAKEKYDERLISQIKIMTKVMFLYIPLPMFWALFDQQGSRWTLQATTMTGKIGTIEIQPDQMQTVNAILIVIMVPIVDAVVYPLIAKCG-FNFTSLKKMTVGMFLASMAFVVAAIVQVEIDKT----LPVFPSGNQVQIKVLNIGNNDMAVYFPGKN-VTVAQMS--------------------------QTDTFMTFDVDQLTSINVSSPGSPGVTTVAHEFEPGHRHTLLVWGPNLYRVVKDGLNQKPEKGENGIRFVSTLNEMITIKMSGKVYENVTSHSASNYQFFPSGQKDYTINTTEIAPNCSSDFKSSNLDFGSAYTYVIRSRASDG---CLEVKEFEDIPPNTVNMALQIPQYFLLTCGEVVFSVTGLEFSYSQAPSNMKSVLQAGWLLTVAIGNIIVLIVAEAGHFDKQWAEYVLFASLLLVVCIIFAIMARFYTYINPAEIEAQFDE----DEKKKG---VGKENPYSSLEPV----SQTNM------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P46059-1", "uniprot_id": "S15A1_HUMAN", "id": "P46059-1", "name": "Solute carrier family 15 member 1", "aln": "---------------------------------------------------------------------------------------------------------------------MGMSKSHSFFG---YPLSIFFIVVNEFCERFSYYGMRAILILYFTN--------FISWDDNLSTAIYHTFVALCYLTPILGALIADSWLGKFKTIVSLSIVYTIGQAVTSVSSINDLTDHNHDGTPDSLPVHVVLSLIGLALIALGTGGIKPCVSAFGGDQFEE----------------GQEKQRNRFFSIFYLAINAGSLLSTIITPMLRVQQCGIHSKQACYPLAFGVPAALMAVALIVFVLGSGMYKKFKPQG-NIMGKVAKCIGFAIKNRFRHRSKAFPKREHWLDWAKEKYDERLISQIKMVTRVMFLYIPLPMFWALFDQQGSRWTLQATTMSGKIGALEIQPDQMQTVNAILIVIMVPIFDAVLYPLIAKCG-FNFTSLKKMAVGMVLASMAFVVAAIVQVEIDKT----LPVFPKGNEVQIKVLNIGNNTMNISLPGEM-VTLGPMS--------------------------QTNAFMTFDVNKLTRINISSPGSP-VTAVTDDFKQGQRHTLLVWAPNHYQVVKDGLNQKPEKGENGIRFVNTFNELITITMSGKVYANISSYNASTYQFFPSGIKGFTISSTEIPPQCQPNFNTFYLEFGSAYTYIVQ-RKNDS---CPEVKVFEDISANTVNMALQIPQYFLLTCGEVVFSVTGLEFSYSQAPSNMKSVLQAGWLLTVAVGNIIVLIVAGAGQFSKQWAEYILFAALLLVVCVIFAIMARFYTYINPAEIEAQFDE----DEKKNR---LEKSNPYFMSGAN----SQKQM------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AC58JSS5-1", "uniprot_id": "A0AC58JSS5_DANRE", "id": "A0AC58JSS5-1", "name": "Solute carrier family 15 member 1", "aln": "-------------------------------------------------------------------------------------MNEASLHLTILSPVDQKTVSVGGVTMADKEGHKQKKERASCFG---YPVSIFFIVVNEFCERFSYYGMKAVLVLYFKY--------FIGWDDDLSTTIYHTFVALCYLTPIMGAIIADSWLGKFKTIVYLSIVYTIGQVIMAISAIHDITDANRDGKPDNKTLHISLSMLGLILIALGTGGIKPCVAAFGGDQFED----------------HQEKQRSTFFSIFYLSINAGSLLSTLITPILRSQECGIYAKQSCYPLAFGVPAALMVVALIVFVIGHKMYIMESPKG-NILLQVINCIGFALNNRFRHRGKQYPKREHWMDWAEEKYDKLLIAQVKMVVKVLFLYIPLPMFWALFDQQGSRWTIQATTMDGNFGGFVIQPDQMQIVNPILIVIMVPIMDSAIYPLIKLCR-INFTPLRKMTVGMVLAALAFVAAALLQLQIDET----MPKFPSTSQTQLKFLNVESTSLPVVVEGQDQFMVPGFN--------------------------ASSEYLTLDKENVT----ISAG---GVNDTAFLKTGTRHTVLMN-AAGMRNTLDDLTEKPEQGLNAIRFVNGWENRLNVSVK-SDNVHADPLDASVYLLVPHGKVNFTIFD-GGDGKCHYIMQ---LGFGSTYTVLIPSTFAFGQTCSESFEAVQDMEPNRIHMAWQVIQYFLLTCGEVVYSVTGLDFSYSQAPSNMKSVLQAGWLLTVAVGNIIVLIVAEAGSLPDQWAEYLLFASLLVAVSIIFAIMAYFYTYIDPNEIEAKFKELEPEDKKRKEMQMTAKDNMAYVHNEN-TNIKQTKI------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0AC58GFH5-1", "uniprot_id": "A0AC58GFH5_DANRE", "id": "A0AC58GFH5-1", "name": "Solute carrier family 15 member 1", "aln": "-------------------------------------------------------------------------------------MPDS--------------------KMDETK--KKKKKTAECCG---YPISIFFIVVNEFCERFSYYGMRAVLVLYFRY--------FLLWDDDLATSIYHAFVALCYLTPILGAIIADSWLGKFKTIIYLSIVYAVGQVVMAVSTIHDITDANRDGTPDNFTLHIALSMLGLVLIALGTGGIKPCVAAFGGDQFQE----------------HQSRQLNTFFSVFYLCINAGSLLSTLITPVLRAQECGIHTQQQCYPLAFGVPAALMVVSLVVFIAGSGMYTKTAPEG-NIMGSVCKCIWFALNNRFRHRSDIYPKREHWMDWAEEKYDKLLIAQIKMVLKVLFLYIPLPMFWTLFDQKGSRWTLQATTMTGDFGGFVLQPDQMQTVNPILILTLVPIMDRIIFPLIKKCG-LNFSPLKRMTVGMLFAATAFIAAALVQMEIDKT----LPNFPSSSESQLKVVNMHSESLIVTVPSQEPLLIGSFEVQHTSKHTTAVSHWCFTISSHVVFPQSSPDYITFDQQDIR----LAFNTTPEINKDLSLIKGSRQTLIIPSEPAEMYLKEDIKSKPKEGKNAVRFVNGWTAYLNITNL-ESSLQ--PSETSNYTLVSQGMRKFTLTD-GIQS-CEFSRK---FGFGSSYTFLIPSDLFS--TDCESIKEIEDMQPNSVHMALQIPQYFLITTGEVMFSVTGLQFSYSQAPKNMKSVLQAGWLCTNAVGNIIVLIVAELGKLPKQWAEYVLFASLLVAVSIIFSIMAYFYTYIDPAEIEAEILKQQETDPDKK----KKKETLEMEEKENEQEIKQTKI------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "X2JCG8-1", "uniprot_id": "X2JCG8_DROME", "id": "X2JCG8-1", "name": "Oligopeptide transporter 1", "aln": "MELPAEQVPLLEIQPAAEPVAEPEPSPAAEIAPASPDGSGPSAAAAEEVTPSVATVEDTTPIAAPAESQPSGESNGTAEAKKLPEIAKKNGKEPDQNDKEPDQNGKELAETNDFKNVSETEGQQKKLP---YPKSVFFIISNEFCERFNYYGMRTVLVLYLSR--------VLGYSDDTATVVFHIFTMFVYFLCVFGAIISDSWLGKFKTILYLSLVYICGSVLLTLGAIGPLNLP-----------METFTMLGLALIALGSGGIKPCVSAFGGDQFKVP---------------EQVKQITSFFSLFYFSINAGSLISTTVTPILR-EDVSCFDDINCYPLAFGVPAVLMIVSVIIFVLGRSLYKMKPPAG-NMVVLVSSTIWTALTTKCKEKKT--NPREHWLDYADKKYDRQLIDDVKVLMRVLFLYLPLPVFWALFDQQGSRWTFQATRMDGDMGSWDIKPDQLQVLNPLLILIFIPLYDVALYPALKLVG-IRR-PLQKLTMGGILAGIAFIISGVVELSLEKT-YPDLPYS-QNIQLRIFNADNCDYFFTSNIPGAENVTVTSLNAYTN-----------------KDIYAPGSLDVEFSLSSASEACTISADKIPKVLTDNTAWSLFLNPLNGSGYYWEEDFVDKPSQSHPLIRNVANVPQELSIRWEKASTGEVVYD-DLASKTLLTRVNSAEYVVMVGE--------RNVGTFDVHTGGVYTLLIK-DNNNI----YEANLEEVTSPNSVKILWLVPQYVVMTLGEVMFSVTGLEFSYAQAPPSMKSVLQACWLLTVAFGNVIVVVIAEAALFESQASEFFLFAGLMFADMLIFMVMAYYYVPNDPNK-VEEAQPLTAGDAKTEIP---------ALEGGVENK-----------GKDINE-", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P91679-1", "uniprot_id": "PEPT1_DROME", "id": "P91679-1", "name": "Peptide transporter family 1", "aln": "--------------------------------------------MASEIT------------------------NG------------KNG-----------QNGK-----NGQKEESDSQ-IAPPIP---YPKSVAFIISNEFCERFNYYGMRTILVLYLTN--------KLGYNEETATVLFHTFTMLVYIFPLIGALIADGWLGKYKTILYLSLVYSLGAMVVSFGAVPLSGMP-----------TKAVTVVGLLLIAIGTGGIKPCVSAFGGDQFSLP---------------AQSFQLAKFFSLFYFAINAGSLISTTFTPILR-ADVHCFGDQDCFSLAFGVPAILMIFSVIIFMAGKRLYRCQPPAG-NMIFGVSRCIADAFKGWQKRRHS--EPMESFLDYAKPTVGSRMVQETKCLGRILRLFLPFPVFWALFDQQGSRWTFQATRMDGNVLGFQIKPDQMQVVNPLLILGFLPLFDYIIYPALARCG-IRR-PLQKLTLGLLLAALGFFLSAGLEMKMEQAAYRATPIEPDMTHLRIYNGMPCRYEISSAVVQTPRVIEP-LNVWED-----------------LSLQMTESKEYTFNAQPVSGECPSIIDKLRLQPGKSVSYFLAQDKLVEFADGLQMAATDTGRTSVRALLNTPDGEGPVLLSTESATSQEPPLTLDKGNVPQLHRITPGFARVDING--------KKVASFEAKEGRLYSILVTGSARDG----YQHNVIEVVALSTVSILWQLPQIVVMTAAEVMFSVTGLEFSYSQSPPSMKSVLQACWLLSVAIGNMLVVVIAEFKFTSSQSGEFTLFASLMLVDMMIFLWLARSYQYKDQREDFEDDDDATIDSVMQSKPKATTVDTTARKTNGIEAEPGYGAYRNHAYDNDFSEA", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VH93-1", "uniprot_id": "Q9VH93_DROME", "id": "Q9VH93-1", "name": "Peptide transporter family 1", "aln": "--------------------------------------------------------------MFRATEIGSEETLPALAELSQVGYERDARDVEWVAWRGERAQLKLAHRSSLPNYGFAPPTIRMKYR---YPRAVFFVLATKFFEAFAANGIRTVLALYLRD--------DLNFTESFSTVVLHIFNFFGQFCPIIGAILADSYIGNVRTISGFSFIYAFGWLLLTLTSLPAMGLP-----------MVLLVSIALLFIAVGNGSIRACITSLGALQFKLP---------------EQSVHLAEYFSFYYFVYYFGIFLSKILPPLVR-ANTQCFDKAECYPAVFGTLGAAFMMAWFIFLVGKWFYKSEKLSDDNILFKFCGCIKTALVEKWRRRKS-TKRSNYWLHNAVVAYDMGFVNDVSRVLRISKLFIPLPFYFALLAQQDSSWTFQATQMNTTLMGVTIQPDQAKAVGPIFLFMLIPLWQYITVPLLRRYFNWELQPLHSVTVGGIFSAGAFFCAGALQERIKNS---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------PPQTVNIAWQLPQFLLLMMGELLLSIPGLQFAFTQAPTSMKSVVTAAWFLNNAFGNLIVVLVTELGMLSSQMAEYFFYAVVMLVCIILYALLAFDYTLQERKAGMYVRMDSEAEDRDVPS---------TSRSGSI---------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P32901-1", "uniprot_id": "PTR2_YEAST", "id": "P32901-1", "name": "Peptide transporter PTR2", "aln": "------------------------------------------------------MLNHPSQGSDDAQDEKQGDFPVIEEEKTQAVTLKDSYVSDDVANSTERYNLSPSPEDEDFEGPTEEEMQTLRHVGGKIPMRCWLIAIVELSERFSYYGLSAPFQNYMEYGPNDSPKGVLSLNSQGATGLSYFFQFWCYVTPVFGGYVADTFWGKYNTICCGTAIYIAGIFILFITSIPSVGNRDS---------AIGGFIAAIILIGIATGMIKANLSVLIADQLPKRKPSIKVLKSGERVIVDSNITLQNVFMFFYFMINVGSLS------LMATTELEYHKG---FWAAYLLPFCFFWIAVVTLIFGKKQYIQR-PIGDKVIAKSFKVCWILTKNKFDFNAA----KPSVHPEKNYPWNDKFVDEIKRALAACKVFIFYPIYWTQYGTMISSFITQASMMELHG----IPNDFLQAFDSIALIIFIPIFEKFVYPFIRRYT--PLKPITKIFFGFMFGSFAMTWAAVLQSFVYKAG----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------PWYNEPLGHNTPNHVHVCWQIPAYVLISFSEIFASITGLEYAYSKAPASMKSFIMSIFLLTNAFGSAIGCALSPVTVDPKFTWLFTGLAVACFISGCLFWLCFRKYNDTEEEMNAMDYEEEDEFDLNPIS---APKANDIEILEPMESLRSTTKY------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * :: :: * * *: : : *: : .. :* : : * . ::*. ::* : *: .** : :* * : . :: .: :*.:..* *:. :: : . *: . * .:*: * : :: : . : .: : .: . :: * * . ::: . . :: : . ::: *.::: * : **: * : * : ...: :. ::*: : * : .: : .* .:.. .: :. :: : :: . : : : .:: .*:. *:.**:::::::* .***.: : :: . *.*. : :: . : * . :: * : . ", "identical_positions": 44, "similar_positions": 148, "identity": "4.82%" }, { "cls_id": "homologset.agr.MGI:1861377", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9NSA1-1", "uniprot_id": "FGF21_HUMAN", "id": "Q9NSA1-1", "name": "Fibroblast growth factor 21", "aln": "MDSDETG-FEHSGLWVS-VLAGLLLG-----------------------------ACQAHPIP-------DSSPLLQFGGQVRQRYLYT---------DDAQQTEAHLEIREDGTVGGAADQSPESLLQLKALKPGVIQILGVKTSRFLCQRPDGALYGSLHFDPEACSFRELLLEDGYNVYQSEAHGLPLHLPGNKSPHRDPAPRGPARFLPLPGLPPALPEPPGILAPQPPDVGSSDPLSMVGPSQGRSPSYAS", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9JJN1-1", "uniprot_id": "FGF21_MOUSE", "id": "Q9JJN1-1", "name": "Fibroblast growth factor 21", "aln": "MEWMRSR-VGTLGLWVRLLLAVFLLG-----------------------------VYQAYPIP-------DSSPLLQFGGQVRQRYLYT---------DDDQDTEAHLEIREDGTVVGAAHRSPESLLELKALKPGVIQILGVKASRFLCQQPDGALYGSPHFDPEACSFRELLLEDGYNVYQSEAHGLPLRLPQKDSPNQDATSWGPVRFLPMPGLLHEPQDQAGFLPPEPPDVGSSDPLSMVEPLQGRSPSYAS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0ABK0LY65-1", "uniprot_id": "A0ABK0LY65_RAT", "id": "A0ABK0LY65-1", "name": "Fibroblast growth factor", "aln": "MVVDDGGGTSVDGVQLTAVVASILWTHHRLGQSLSPVEEDFWTQPFSQAAEVCIMACPPYLQPPERWKKKEPAESTQTDRNARQSCFRLGVHIATGRRDDDQDTEAHLEIREDGTVVGTAHRSPESLLELKALKPGVIQILGVKASRFLCQQPDGTLYGSPHFDPEACSFRELLLKDGYNVYQSEAHGLPLRLPQKDS--QDPATRGPVRFLPMPGLPHEPQEQPGVLPPEPPDVGSSDPLSMVEPLQGRSPSYAS", "tax_id": 10116, "tax_name": "Rat" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* *: : ::* :* . .: * :.: * . :.** : ** *:************* *:*.:******:***************:******:***:**** **************:***************:** :.* :*.:. **.****:*** : .*.*.*:************* * *********", "identical_positions": 128, "similar_positions": 38, "identity": "50.0%" }, { "cls_id": "homologset.agr.MGI:1861379", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P52905-1", "uniprot_id": "TRYI_DROME", "id": "P52905-1", "name": "Trypsin iota", "aln": "-----MAVYGIVATVLVLLLLGD-----ASDVEATGRIIGGSDQLIRNAPWQVSIQI-SARHECGGVIYSKEIIITAGHCLHERSVTLMKVRVGAQNHNYGGTLVPVAAYKVHEQFDS-RFLHYDIAVLRLSTPLTFGLSTRAINLASTSPSGGTTVTVTGWGHTDN--GALS-DSLQKAQLQIIDRGECASQK---FGYGADFVGEETICAAS--TDADACTGDSGGPLVASSQLVGIVSWGYR-CADDNYPGVYADVAILRPWIVKAANAI", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VQ97-1", "uniprot_id": "Q9VQ97_DROME", "id": "Q9VQ97-1", "name": "trypsin", "aln": "-----MLLHWLVLVASVTLISAG-----SS----PERIVGGHPVLISEVPWQAALMY-SEKYICGAVIYSDKIIITAAHCVERPFDTLYSVRVGSVWKNLGGQHARVAVIRKHEDYVSSTILFNDIAVIRLVDTLIFNAEVRPIQLADSAPAAGTEASVSGWGEIGI--LWLQPTSLLKTSVKILDPNVCKRS------Y--QYITKTMICAAA--LLKDSCHGDSGGPLVSGGQLVGIVSYGIG-CANPFFPGVYANVAELKPWILNAIEQL", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P42278-1", "uniprot_id": "TRYT_DROME", "id": "P42278-1", "name": "Trypsin theta", "aln": "--MHRLVVLLVCL-AVGSACAGTVGVSNGDPFEREGRIVGGEDTTIGAHPYQVSLQTKSGSHFCGGSLINEDTVVTAAHCLVGRKVSKVFVRLGSTLYNEGGIVVAVRELAYNEDYNS-KTMEYDVGILKLDEKVKETENIRYIELATETPPTGTTAVVTGWGSKCYFWCMTLPKTLQEVYVNIVDWKTCASDE---YKYG-EIIYDSMVCAYE--KKKDACQGDSGGPLAVGNTLVGIVSWGYA-CASNLLPGVYSDVPALRKWILNASETL", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9W5U8-1", "uniprot_id": "Q9W5U8_DROME", "id": "Q9W5U8-1", "name": "Peptidase S1 domain-containing protein", "aln": "--MNRLLLSVVALVALAASCHGNPGLD--FPF---GRIVNGEDVDIENYPYQVSVQTTKGSHFCGGSLIDSETVLTAAHCMQSYAASELQVRVGSTSRSSGGEVVTVRAFKYHEGYNS-KLMINDVAIIKLSSPVRQTSKIRAIELADSEAVSGTNAVVSGWGTTCFLFCSS-PDTLQKVEVDLLHYKDCAADT---YNYGSDSILETMVCATG--EKKDACQGDSGGPLVADNKLVGVVSWGSG-CAWTGYPGVYADVASLRSWIVDTTDSL", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "C0HKA3-1", "uniprot_id": "TRYGT_DROME", "id": "C0HKA3-1", "name": "Trypsin gamma", "aln": "-----MLKFVILLSAVACALGGT--VPEGLLPQLDGRIVGGSATTISSFPWQISLQR-SGSHSCGGSIYSSNVIVTAAHCLQSVSASVLQIRAGSSYWSSGGVTFSVSSFKNHEGYNA-NTMVNDIAIIKINGALTFSSTIKAIGLASSNPANGAAASVSGWGTLSY-GSSSIPSQLQYVNVNIVSQSQCASST---YGYG-SQIRSTMICAAA--SGKDACQGDSGGPLVSGGVLVGVVSWGYG-CAYSNYPGVYADVAALRSWVISNA---", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "C0HKA4-1", "uniprot_id": "Y0031_DROME", "id": "C0HKA4-1", "name": "Trypsin delta/gamma-like protein CG30031", "aln": "-----MLKFVILLSAVACALGGT--VPEGLLPQLDGRIVGGSATTISSFPWQISLQR-SGSHSCGGSIYSSNVIVTAAHCLQSVSASVLQIRAGSSYWSSGGVTFSVSSFKNHEGYNA-NTMVNDIAIIKINGALTFSSTIKAIGLASSNPANGAAASVSGWGTLSY-GSSSIPSQLQYVNVNIVSQSQCASST---YGYG-SQIRSTMICAAA--SGKDACQGDSGGPLVSGGVLVGVVSWGYG-CAYSNYPGVYADVAALRSWVISNA---", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "C0HKA2-1", "uniprot_id": "TRYDT_DROME", "id": "C0HKA2-1", "name": "Trypsin delta", "aln": "-----MLKFVILLSAVACALGGT--VPEGLLPQLDGRIVGGSATTISSFPWQISLQR-SGSHSCGGSIYSSNVIVTAAHCLQSVSASVLQIRAGSSYWSSGGVTFSVSSFKNHEGYNA-NTMVNDIAIIKINGALTFSSTIKAIGLASSNPANGAAASVSGWGTLSY-GSSSIPSQLQYVNVNIVSQSQCASST---YGYG-SQIRSTMICAAA--SGKDACQGDSGGPLVSGGVLVGVVSWGYG-CAYSNYPGVYADVAALRSWVISNA---", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "A1Z8J8-1", "uniprot_id": "A1Z8J8_DROME", "id": "A1Z8J8-1", "name": "trypsin", "aln": "-----MLKFVILLSAVACALGGT--VPEGLLPQLDGRIVGGSATTISSFPWQISLQR-SGSHSCGGSIYSSNVIVTAAHCLQSVSASVLQIRAGSSYWSSGGVTFSVSSFKNHEGYNA-NTMVNDIAIIKINGALTFSSTIKAIGLASSNPANGAAASVSGWGTLSY-GSSSIPSQLQYVNVNIVSQSQCASST---YGYG-SQIRSTMICAAA--SGKDACQGDSGGPLVSGGVLVGVVSWGYG-CAYSNYPGVYADVAALRSWVINNA---", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P35004-1", "uniprot_id": "TRYB_DROME", "id": "P35004-1", "name": "Trypsin beta", "aln": "-----MLKFLILLSAVACALGGT--IPEGLLPQLDGRIVGGTATTISSFPWQISLQR-SGSHSCGGSIYSARVIVTAAHCLQSVSASSLQIRAGSSYWSSGGVVAKVSSFKNHEGYNA-NTMVNDIAVLHLSSSLSFSSTIKAIGLASSNPANGAAASVSGWGTESS-GSSSIPSQLRYVNVNIVSQSRCSSSS---YGYG-NQIKSSMICAFA--SGKDSCQGDSGGPLVSGGVLVGVVSWGYG-CAAANYPGVYADVAALRSWVINNA---", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P35005-1", "uniprot_id": "TRYE_DROME", "id": "P35005-1", "name": "Trypsin epsilon", "aln": "-----MLKFAVLLSVLACALAGT--IPDGLLPQLDGRIVGGYETSIDAHPYQVSLQR-YGSHFCGGSIYSHDIVITAAHCLQSIEAKDLKIRVGSTYWRSGGSVHSVRSFRNHEGYNS-RTMVNDIAIIRIESDLSFRSSIREIRIADSNPREGATAVVSGWGTTES-GGSTIPDHLLAVDLEIIDVSRCRSDE---FGYG-KKIKDTMLCAYA--PHKDACQGDSGGPLVSGDRLVGVVSWGYG-CGDVRYPGVYADVAHFHEWIERTAEEV", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9Y5K2-1", "uniprot_id": "KLK4_HUMAN", "id": "Q9Y5K2-1", "name": "Kallikrein-4", "aln": "-MATAGNPWGWFLGYLILGVAGS------LVSGSCSQIINGEDCSPHSQPWQAALVM-ENELFCSGVLVHPQWVLSAAHCFQNSYTIGLGLHSLEADQEPGSQMVEASLSVRHPEYNR-PLLANDLMLIKLDESVSESDTIRSISIASQCPTAGNSCLVSGWGLLAN---GRMPTVLQCVNVSVVSEEVCSKLYDPLY-------HPSMFCAGGGHDQKDSCNGDSGGPLICNGYLQGLVSFGKAPCGQVGVPGVYTNLCKFTEWIEKTVQAS", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9Z0M1-1", "uniprot_id": "KLK4_MOUSE", "id": "Q9Z0M1-1", "name": "Kallikrein-4", "aln": "MMVTARTPWGWFLGCLILEVTGA------SASSVSSRIIQGQDCSPHSQPWQAALFS-EDGFFCSGVLVHPQWVLSAAHCLQESYIVGLGLHNLKGSQEPGSRMLEAHLSIQHPNFND-PSFANDLMLIKLNESVIESNTIRSIPVATQCPTPGDTCLVSGWGQLKN---GKLPSLLQCVNLSVASEETCRLLYDPVY-------HLSMFCAGGGQDQKDSCNGDSGGPIVCNRSLQGLVSMGQGKCGQPGIPSVYTNLCKFTNWIQTIIQTN", "tax_id": 10090, "tax_name": "Mouse" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . :*: * *:* :: *.. : :::*.**. :: *. . : : : *: :::: : : * :* . * *:*** * . :.: * .** *:* ******: . * *:** * *. *.**::: : *: ", "identical_positions": 39, "similar_positions": 47, "identity": "14.29%" }, { "cls_id": "homologset.agr.MGI:1861380", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9JIA7-1", "uniprot_id": "SPHK2_MOUSE", "id": "Q9JIA7-1", "name": "Sphingosine kinase 2", "aln": "---------------------------------------------------------------------------------------------------------MAPPPLL--PVAASTPILHG--EFGSYPANGPRFALTLTTQALHIQRLR-PKPEARPRDGLVSLDEVSGCGTLQSRSPE------------------------------DTAAYFCIYTYPR-----GRRGGRRRATRTFRADGATTYEENRAEAQRWATALTCLLRGVPLSGDQ---------EITPELLPRKPRLLILVNPFGGRGLAWQRCMDHVVPMISEAGLSFNLIQTERQNHARELVQGLS--LSEWEGIVTVSGDGLLYEVLNGLLDRPDWEDAV-RMPIGVLPCGSGNALAGAVNHHGGFEQVVGVDLLLNCSLLLCRGGSHPLDLLSVTLASGS---------------RCFSFLSVAWGFLSDVDIHSERFRALGSARFTLGAVLGLASLHTYRGRLSYLPATTEPALPIPGHSLPRAKSELVLAPAPAPAATHSPLHRSVSDLPLPLPQPALVSPG--------------------------------------------SPEPLPDLS------------------------LNGGGP-ELTG----------------DWGG--------------AGDAP------------------------------------------------------------------------------------------------------LSPDPLLPSSPNALKTAQLSPIAEGPPEMPASSGF-LPPTHSAPEASTWG---------------PVDHLLPPLGSPLPQ--DWVTIEGEFVLMLGILPS----HLCADLMAAPHARFDDGVVHLCWVRSGISRAALLRILLAMEHGNHFSLG-CPHLGYAAARAFRLEPLTPRGLLTVDGELVEYGPIQAQVHPGLATLLTGPAGQKPQA----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9NRA0-1", "uniprot_id": "SPHK2_HUMAN", "id": "Q9NRA0-1", "name": "Sphingosine kinase 2", "aln": "---------------------------------------------------------------------MNGHLEAEEQQDQRPDQELTGSWGHGPRSTLVRAKAMAPPPP---PLAASTPLLHG--EFGSYPARGPRFALTLTSQALHIQRLR-PKPEARPRGGLVPLAEVSGCCTLRSRSPS------------------------------DSAAYFCIYTYPR-----GRRGARRRATRTFRADGAATYEENRAEAQRWATALTCLLRGLPLPGDG---------EITPDLLPRPPRLLLLVNPFGGRGLAWQWCKNHVLPMISEAGLSFNLIQTERQNHARELVQGLS--LSEWDGIVTVSGDGLLHEVLNGLLDRPDWEEAV-KMPVGILPCGSGNALAGAVNQHGGFEPALGLDLLLNCSLLLCRGGGHPLDLLSVTLASGS---------------RCFSFLSVAWGFVSDVDIQSERFRALGSARFTLGTVLGLATLHTYRGRLSYLPATVEPASPTPAHSLPRAKSELTLTPDPAPPMAHSPLHRSVSDLPLPLPQPALASPG--------------------------------------------SPEPLPILS------------------------LNGGGP-ELAG----------------DWGG--------------AGDAP------------------------------------------------------------------------------------------------------LSPDPLLSSPPGSPKAALHSPVSEGAPVIPPSSGLPLPTPDARVGASTCG---------------PPDHLLPPLGTPLPP--DWVTLEGDFVLMLAISPS----HLGADLVAAPHARFDDGLVHLCWVRSGISRAALLRLFLAMERGSHFSLG-CPQLGYAAARAFRLEPLTPRGVLTVDGEQVEYGPLQAQMHPGIGTLLTGPPGCPGREP---", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AB32TA20-1", "uniprot_id": "A0AB32TA20_DANRE", "id": "A0AB32TA20-1", "name": "sphingosine kinase", "aln": "-----------------------------------------------------------------------MRSPGPDSPSMTEEALLHGQFG----------GWSSGGGSG--SNSNSCPNSPGGVSLPSSPAS-TNYALTLTPTHIHVQRLS-PRAGKQSR-LLLPMAELTGCSCPRSPAP----------------------------------PLLVLYWYPP-----GRR--RKGVSRHRQVR--AYLAESRAEAEKWNAAIQSLLRGMDVSSTT---------EFCKSMLPRPRRLLLLVNPFSGRGQAMQWCQTHILPMIREANISYNLIQTERQNHARELIREIS--LPEWDGIVIVSGDGLLHEVINGLMERPDWEQAI-KTPVGILPCGSGNALAGSINHHAGYDMCLREPLLLNCCFLLCRGGVKPLDLVSVTTSPCASSSTSNQNGHPPAPRRLFSFLSVAWGFVSDVDIESERYRGLGSARFTLGTLVRLASLRSYKGRLSYLPPAVVNPSPDATPQPPRRPLSRSITEG-LEGFCRTPIHRTCSDMGLSEQRSLRKDDGERERERERERQERERERERRRDRARGVGVVRASSLAEDREREVEAEEKMEEMSGTSSESTERDECDNIAKNNGNEEENNSGES-KIDGQELTNARNLSDTNEVNDCDGSYQTTPPELQHALRKNSAPSSQIINAFFSQPIGADTDQDLELAAYGKEDEDINGTYFQKEAYSLDKSRERALTISSSPFRQSPFKAFKPKTLDQNQNPSRPRPLSLLHQSHSNSLPPKFPSLSPTPPSSPSCASPHSSYLAPRPNTPSSSSPSPSIHSPTPSFNFDLAEPAGPLKNRPHMTSSINLPEDDLLPPLDQPLPTR-DWVTIEGDFVLVLAIYQS----HLGADLLAAPQARFDDGLIHLTFVRAGISRATLLRLFLAMERGAHLSLS-SPYVSHVSARAFRLQPLSPRGTLTVDGELVPYGPLQAQVHPSMARLIVGDSGIKITRF---", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VYY8-1", "uniprot_id": "Q9VYY8_DROME", "id": "Q9VYY8-1", "name": "sphingosine kinase", "aln": "----------------------------------------------------------------MTANTGTSGENLMGNGGKTHEPSTPTSDTEVASGTPTELSEIFFVDNS--RRKQSIKIQVKLCPEGVYLRRETEEDDHINEQLIRIDDIIGSRYGRRLKKR--ARGGLNSCR--NPNVPGQEADSEPD---------------------SDNSAYLYIYAYLKKEKPLR----RVQTLRILRFRSSNDYGVNLQTAEMWHHTIRKHKRGN----------------GSSSPADCGKQLLILLNPKSGSGKGRELFQKQVAPLLTEAEVQYDLQITTHPQYAKEFVRTRRDLLTRYSGIVVASGDGLFYEVLNGLMERMDWRRACRELPLGIIPCGSGNGLAKSVAHH--CNEPYEPKPILHATLTCMAGKSTPMDVVRVELATRDKHF------------VMYSFLSVGWGLIADIDIESERLRSIGAQRFTLWAIKRLIGLRSYKGRVSYLLGKGKKEPP------VEAARELPAESTAAGIRSSLPLNAGEFHDLPEEEEGEAVLDG---------------------------------------------EQFADAIS------------------------LDRSV---------------------------------------------------------------------------------------------------------------------------------------------------YRQHADSWHSAMSRRTAYYSLGGPSMRSNRSRMSISQRIEAANAEFAER----------------VPTGTIPPLQMPLLSSDGWICEDGDFVMVHAAYTT----HLSSDVFFAPESRLDDGLIYLVIIRRGVSRHQLLNFMLNLNAGTHLPIGEDPFIKVVPCRAFRIEPSSSDGILVVDGERVEYGPIQAEVMPGLINVMTTSGQ---------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VZW0-1", "uniprot_id": "Q9VZW0_DROME", "id": "Q9VZW0-1", "name": "sphingosine kinase", "aln": "-----------------------------------------------------------------------MSESLDKTTSPSSASSRATPPGTQDADEGHDVSDTFYTSQ---RKKGSHVFRVRLDATGFTLQRESPGGSIVKEQHVRISDIVGARCMRPKKSRRLAMSGACACSSGNPNSPAISASGDHHRPATTPSKCSTNSRDNIPSDGGDVSAFLYVFAYVLKKRSLRSELHRERTVLTLRFRSFDTFEDNMREADRWYRSLRWQLHRTLE--EI---------FVAPTVDERRRRVLVLLNPKSGSGDAREVFNMHVTPVLNEAEVPYDLYVTKHSNFAIEFLSTR--CLDAWCCVVAVGGDGLFHEIVNGLLQRQDWAHVLPHLALGIIPCGSGNGLARSIAHC--YNEPYFSKPVLGAALTVISGRSSPMDVVRVQLQSRS----------------LYSFLSIGWGLISDVDIESERIRMLGYQRFTVWTLYRLVNLRTYNGRISYLLT-DHEVSS------THSATGYAAQRRMQSSRSCN-THIDMLNGPAPIYHSSAEYLP---------------------------------------------QEFADVIS------------------------LETSINQ------------------------------------------------------------------------------------------------------------------------------------------------SFRSRCDSWLSGGSRRSFYYSIS-ESIYHSLADESEFAGLAAASLENRQQN--------------YGPASELPDLNEPLSEDQGWLVEEGEFVMMHAVYQT----HLGIDCHFAPKAQLNDGTIYLILIRAGISRPHLLSFLYNMSSGTHLPESHDDHVKVLPVRAFRLEPYDNHGIITVDGERVEFGPLQAEVLPGIARVMVPK-----------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q06147-1", "uniprot_id": "LCB5_YEAST", "id": "Q06147-1", "name": "Sphingoid long chain base kinase 5", "aln": "MTLKPSKRRKGRSRHSRKKQITSAILTEEGIMIKAKPSSPYTYANRMADKRSRSSIDNISRTSFQSNISRTSFQSNSDNNSIFETASLISCVTCLSDTDTIDRSETSTTDTSKDDLSANPKLHYPSVNGQLPANTVIPYGRILDARYIEKEPLHYYDANSSPSSPLSSSMSNISEKCDLDELESSQKKE-------------------------RKGNSLSRGSNSSSSLLTSR--SPFTKLVEVIFARPRRHDVVPKRVSLYIDYKPHSSSHLKEEDDL----VEEILKRSYKNTRRNKSIFVIINPFGGKGKAKKLFMTKAKPLLLASRCSIEVVYTKYPGHAIEIAREMD--IDKYDTIACASGDGIPHEVINGLYQRPDHVKAFNNIAITEIPCGSGNAMS---------VSCHWTNNPSYSTLCLIKSIETRIDLMCCSQPSYAREHP------------KLSFLSQTYGLIAETDINTEFIRWMGPARFELGVAFNIIQKKKYP----------------------CEIYVKYAAKSKNELKNHYLEHK--NKGSLEFQHITMNKDN---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------EDCDNYNYENEYETENEDEDEDADADDEDSHLISRDLADSSADQIKEE----------------DFKIKYPLDEGIPS--DWERLDPNISNNLGIFYTGKMPYVAADTKFFPAALPSDGTMDMVITDARTSLTRMAPILLGLDKGSHVLQP---EVLHSKILAYKIIPKLGNGLFSVDGEKFPLEPLQVEIMPRLCKTLLRNGRYVDTDFDSM", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "Q12246-1", "uniprot_id": "LCB4_YEAST", "id": "Q12246-1", "name": "Sphingoid long chain base kinase 4", "aln": "MVVQKKLR---------------AILTDEGVLIKSQ-------SHHMFNKHG-------------------QLRSG-------DSLSLLSCLSCLDDGTLSSDGGSFDEDDSLELLPLNTTIPF---NRILNAKYVNVGQKGFNNGKISSNPFQTENLSSSSENDDVENHSLSNDKAPVSESQSFPKKDKWD----------------------TKTNTVKVSPDDSQDNSPSLGIKDNQQLIELTFAVPKGHDVIPQKLTLLIDHVSRKSRANTGEENISSGTVEEILEKSYENSKRNRSILVIINPHGGKGTAKNLFLTKARPILVESGCKIEIAYTKYARHAIDIAKDLD--ISKYDTIACASGDGIPYEVINGLYRRPDRVDAFNKLAVTQLPCGSGNAMS---------ISCHWTNNPSYAALCLVKSIETRIDLMCCSQPSYMNEWP------------RLSFLSQTYGVIAESDINTEFIRWMGPVRFNLGVAFNIIQGKKYP----------------------CEVFVKYAAKSKKELKVHFLENKDKNKGCLTFEPNPSPNSS---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------PDLLSKNNINNSTKD-----------------------ELSPNFLNED----------------NFKLKYPMTEPVPR--DWEKMDSELTDNLTIFYTGKMPYIAKDTKFFPAALPADGTIDLVITDARIPVTRMTPILLSLDKGSHVLEP---EVIHSKILAYKIIPKVESGLFSVDGEKFPLEPLQVEIMPMLCKTLLRNGRYIDTEFESM", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . . : . : . :::::** .* * . : : *:: : :: * .* :: : : :. ..***: :*::*** * * . . .: :******.:: . : . :*:: . **** :*.::: **.:* * :* ** : . : :.* : . : : .* : :: : :: * * : ** : : . : :: :. * *. : *::: * * : **** . *:*.:: * : : ", "identical_positions": 53, "similar_positions": 94, "identity": "5.21%" }, { "cls_id": "homologset.agr.MGI:1861431", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q6QLQ4-1", "uniprot_id": "CLC7A_MOUSE", "id": "Q6QLQ4-1", "name": "C-type lectin domain family 7 member A", "aln": "MKYHSHIENLDEDGYTQLDFSTQDIHKRPRGSEKGSQAPSSPWRPIAVGLG-ILCFVVVVVAAVLGALGEYGHNSGRNPEEKDNFLSRNKENH-KPTESSLDEKVAPSKASQTTGGFSQPCLPNWIMHGKSCYLFSFSGNSWYGSKRHCSQLGAHLLKIDNSKEFEFIESQTSSHRINAFWIGLSRNQSEGPWFWEDGSAFFPNSFQVRNTAPQESLLHNCVWIHGS------EVYNQICNTSSYSICEKEL--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9BXN2-1", "uniprot_id": "CLC7A_HUMAN", "id": "Q9BXN2-1", "name": "C-type lectin domain family 7 member A", "aln": "MEYHPDLENLDEDGYTQLHFDSQSNTRIAVVSEKGSCAASPPWRLIAVILG-ILCLVILVIAVVLGTMAIWRSNSGSNTLENGYFLSRNKENHSQPTQSSLEDSVTPTKAVKTTGVLSSPCPPNWIIYEKSCYLFSMSLNSWDGSKRQCWQLGSNLLKIDSSNELGFIVKQVSSQPDNSFWIGLSRPQTEVPWLWEDGSTFSSNLFQIRTTATQENPSPNCVWIHVS------VIYDQLCSVPSYSICEKKFSM", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "E7F7Z4-1", "uniprot_id": "E7F7Z4_DANRE", "id": "E7F7Z4-1", "name": "", "aln": "----------------------MQTDKLAEDVEGNPDRVDPYHQQGKVACA-MFTVLLLFSFLVIGIVTGFNFKKSPQEDQNRGLLS---------------DDITPIPFQYKSD--KGLCSDGWLLYKNTCYLLENVYGTWKSSKSLCLSRGAHLMVVDSEEELEFISRVVQKWT--DYWIGLKRDK-MGKWFWVNGDDYHSNLHFWDENQPAHGGMESCVYLKGSDTVNRKLFHDSDCSSQRFHICEHQI--", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q6GV06-1", "uniprot_id": "Q6GV06_DROME", "id": "Q6GV06-1", "name": "", "aln": "--------------MFKYCFICVILAWASRDVLANKTENPLLIDQVAINQQQWFTFIALKESEMQQKIVRIERSIEERLMAMQSKLAYALNELQTIMGNQSVETLEKLRISHRIN--PALFQR---MGTRRFYIEKENKQNWFGASNTCRQLGGHIATIRDEQEFN---EIFSRAPAGVFWIDMNAMFKNGLFAS-SLTGRSPPFFKWKKE--ERGNKFDCVNVYNK------EMYNENCFNTHLFICQAEQWD", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . . : : .: : : : . . *: : : . : . *: . .* .:. * . *.:: : ..:*: . :**.:. : . . . .. .** : . .::. * **: : ", "identical_positions": 13, "similar_positions": 52, "identity": "5.12%" }, { "cls_id": "homologset.agr.MGI:1861434", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9UBX1-1", "uniprot_id": "CATF_HUMAN", "id": "Q9UBX1-1", "name": "Cathepsin F", "aln": "---------MAPWLQLLSLLGLLP--GAVAAPAQPRAASFQAWGPPSPELLAPTRFALEMFNRGRAAGTRAVLG-----------------LVRGRVRRAGQGSLYSLEATLEEPPCNDPMVC------------------------------RLPVSKKTLLCSFQVLDELGRH--VLLRKDCGPVDTKVPGAGEPKSAFTQGSAMISSLSQNHPDNRNETFSSVISLLNE--------------------------------------------------------------DPLSQDLPVKMASIFKNFVITYNRTYESKEEARWRLSVFVNNMVRAQKIQALDRGTAQYGVTKFSDLTEEEFRTIY-LNTLLRKEPGNK-MKQAKSVGDLAPPEWDWRSKGAVTKVKDQGMCGSCWAFSVTGNVEGQWFLNQGTLLSLSEQELLDCDKMDKACMGGLPSNAYSAIKNLGGLETEDDYSYQGHMQSCNFSAEKAKVYINDSVELSQ-NEQKLAAWLAKRGPISVAINAFGMQFYRHGISRPLRPLCSPWLIDHAVLLVGYGN------RSDVPFWAIKNSWGTDWGEKGYYYLHRGSGACGVNTMASSAVVD", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9R013-1", "uniprot_id": "CATF_MOUSE", "id": "Q9R013-1", "name": "Cathepsin F", "aln": "---------MAPLLQLLWLLTLLSTVALSPVPAKPWADDEQAWNLSSQELLAPARFALDMYNYGRAAGTRAVLG-----------------AVRGRVRRAGQGSLFSLEATLEEPPCNDPLVC------------------------------PLPETKKTVLCSFEVLEELKEH--LLLRRDCSPVNAKVT------------------------EFRNATFSSFLPLLDK--------------------------------------------------------------DPLPQDFSVKMAPLFKDFMTTYNRTYESREEAQWRLTVFARNMIRAQKIQALDRGTAQYGITKFSDLTEEEFHTIY-LNPLLQKESGRK-MSPAKSINDLAPPEWDWRKKGAVTEVKNQGMCGSCWAFSVTGNVEGQWFLNRGTLLSLSEQELLDCDKVDKACLGGLPSNAYAAIKNLGGLETEDDYGYQGHVQTCNFSAQMAKVYINDSVELSR-NENKIAAWLAQKGPISVAINAFGMQFYRHGIAHPFRPLCSPWFIDHAVLLVGYGN------RSNIPYWAIKNSWGSDWGEEGYYYLYRGSGACGVNTMASSAVVN", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "F1RE14-1", "uniprot_id": "F1RE14_DANRE", "id": "F1RE14-1", "name": "Cathepsin F", "aln": "MYFNRGYTVIACWVLVGLVLGLED---GPDRPVIGAPGSPVRLSDSDPGVMKAVKFAEERYNMGSNAMHIRRVS-----------------KILSASKQLVKGVRYSIMVEIGSTQCKKAAELSTAD---------------------TCDFFPEPHKQKTEVCLFEVWDIPWENKSTLLKQKCQPAVVKEL-----------------------------KKVAAVPLTHS--------------------------------------------------------------KPMKES--VELLTMFKNFMITYNRTYSSQEEAEKRLRIFQQNMKTAQTLQSLEQGSAEYGITKFSDLTEDEFRMMY-LNPMLSQWSLKKEMKPAIPASAPAPDTWDWRDHGAVSPVKNQGMCGSCWAFSVTGNIEGQWFKKTGQLLSLSEQELVDCDKLDQACGGGLPSNAYEAIENLGGLETETDYSYTGHKQSCDFSTGKVAAYINSSVELPK-DEKEIAAFLAENGPVSAALNAFAMQFYRKGVSHPLKIFCNPRMIDHAVLLVGFGQ------RNGVPFWAIKNSWGEDYGEQGYYYLYRGSGLCGIHKMCSSAIVN", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VN93-1", "uniprot_id": "CATF_DROME", "id": "Q9VN93-1", "name": "Cathepsin F", "aln": "-MRLFAAATVALVLLLGQAAGEELAEERAGQAQGDAESTESSETTTDQAVSEPPITLVHVLNPGEREYLSPNLIGVQNIAMTFLPLSMNFVNIIDAFREITAGVRYEILLNALDTKAIQPAEADIVCRLVILEKPWLRTQWGDKHRELVTSNCTDPAVNSVAGDPAEKARLLNEKYVHRSRRSANDILGRHKPYDEEAAKAQLQKSLDKLTAGEGPHYKIVKVYSASRQVDSGILTRIDADLIDGSEEQHRCIVDIWTKVWVRKDEHEITFKCRNQPVVQARHTRSVEWAEKKTHKKHSHRFDKVDHLFYKFQVRFGRRYVSTAERQMRLRIFRQNLKTIEELNANEMGSAKYGITEFADMTSSEYKERTGLWQRDEAKATGGSAAVVPAYHGELPKEFDWRQKDAVTQVKNQGSCGSCWAFSVTGNIEGLYAVKTGELKEFSEQELLDCDTTDSACNGGLMDNAYKAIKDIGGLEYEAEYPYKAKKNQCHFNRTLSHVQVAGFVDLPKGNETAMQEWLLANGPISIGINANAMQFYRGGVSHPWKALCSKKNLDHGVLVVGYGVSDYPNFHKTLPYWIVKNSWGPRWGEQGYYRVYRGDNTCGVSEMATSAVLA", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :* : : . .. : . . * * : : . :. * :.: .. . .. * :.. : .: ::.. : . : .. . . :: :* .* :.* * * * . ** :* .*: : ::: : *:*:**:*:*:*:*..*:: * . . . * :***.:.**: **:** ************:** : : * * .:*****:***. *.** *** .*** **:::**** * :* * .: : *.*. . : . *:*.: :* : :* .**:* .:** .***** *:::* : :*. :**.**:**:* :. :*:* :***** :**:*** ::**.. **: *.:**:: ", "identical_positions": 122, "similar_positions": 131, "identity": "19.84%" }, { "cls_id": "homologset.agr.MGI:1861437", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9WV60-1", "uniprot_id": "GSK3B_MOUSE", "id": "Q9WV60-1", "name": "Glycogen synthase kinase-3 beta", "aln": "-------------------------MSGRPRTT------------------------SFAESCKPVQQ-----------------------------------------------------------PSAFGSMKVSRDKDGSKVTTVVATPGQGPDRPQEVSYTDTKVIGNGSFGVVYQAKLCDSGELVAIKKVLQDKRFKNRELQIMRKLDHCNIVRLRYFFYSSGEKKDEVYLNLVLDYVPETVYRVARHYSRAKQTLPVIYVKLYMYQLFRSLAYIHSFG-ICHRDIKPQNLLLDPDTAVLKLCDFGSAKQLVRGEPNVSYICSRYYRAPELIFGATDYTSSIDVWSAGCVLAELLLGQPIFPGDSGVDQLVEIIKVLGTPTREQIREMNPNYTEFKFPQIKAHPWTKV----FRPRTPPEAIALCSRLLEYTPTARLTPLEACAHSFFDELRDP-NVKLPNGRDTPALFNFTTQELSSNPPLATILIPPHAR----------------------------------------------IQAAASPPANATAAS-DTNAG----DRGQTNNAAS---------------ASASNST----------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P18266-1", "uniprot_id": "GSK3B_RAT", "id": "P18266-1", "name": "Glycogen synthase kinase-3 beta", "aln": "-------------------------MSGRPRTT------------------------SFAESCKPVQQ-----------------------------------------------------------PSAFGSMKVSRDKDGSKVTTVVATPGQGPDRPQEVSYTDTKVIGNGSFGVVYQAKLCDSGELVAIKKVLQDKRFKNRELQIMRKLDHCNIVRLRYFFYSSGEKKDEVYLNLVLDYVPETVYRVARHYSRAKQTLPVIYVKLYMYQLFRSLAYIHSFG-ICHRDIKPQNLLLDPDTAVLKLCDFGSAKQLVRGEPNVSYICSRYYRAPELIFGATDYTSSIDMWSAGCVLAELLLGQPIFPGDSGVDQLVEIIKVLGTPTREQIREMNPNYTEFKFPQIKAHPWTKV----FRPRTPPEAIALCSRLLEYTPTARLTPLEACAHSFFDELRDP-NVKLPNGRDTPALFNFTTQELSSNPPLATILIPPHAR----------------------------------------------IQAAASPPANATAAS-DTNAG----DRGQTNNAAS---------------ASASNST----------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P49841-1", "uniprot_id": "GSK3B_HUMAN", "id": "P49841-1", "name": "Glycogen synthase kinase-3 beta", "aln": "-------------------------MSGRPRTT------------------------SFAESCKPVQQ-----------------------------------------------------------PSAFGSMKVSRDKDGSKVTTVVATPGQGPDRPQEVSYTDTKVIGNGSFGVVYQAKLCDSGELVAIKKVLQDKRFKNRELQIMRKLDHCNIVRLRYFFYSSGEKKDEVYLNLVLDYVPETVYRVARHYSRAKQTLPVIYVKLYMYQLFRSLAYIHSFG-ICHRDIKPQNLLLDPDTAVLKLCDFGSAKQLVRGEPNVSYICSRYYRAPELIFGATDYTSSIDVWSAGCVLAELLLGQPIFPGDSGVDQLVEIIKVLGTPTREQIREMNPNYTEFKFPQIKAHPWTKV----FRPRTPPEAIALCSRLLEYTPTARLTPLEACAHSFFDELRDP-NVKLPNGRDTPALFNFTTQELSSNPPLATILIPPHAR----------------------------------------------IQAAASTPTNATAAS-DANTG----DRGQTNNAAS---------------ASASNST----------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M3AVR7-1", "uniprot_id": "A0A8M3AVR7_DANRE", "id": "A0A8M3AVR7-1", "name": "Glycogen synthase kinase-3 beta", "aln": "-------------------------MSGRPRTT------------------------SFAESCKPVPQ-----------------------------------------------------------PSAFGSMKVSRDKDGSKVTTVVATPGQGPDRPQEVSYTDTKVIGNGSFGVVYQAKLCDSGELVAIKKVLQDKRFKNRELQIMRKLDHCNIVRLRYFFYSSGDKKDEVYLNLVLDYVPETVYRVARHYSRAKQTLPMVYVKLYMYQLFRSLAYIHSFG-ICHRDIKPQNLLLDPDTAVLKLCDFGSAKQLVRGEPNVSYICSRYYRAPELIFGATDYTSSIDVWSAGCVLAELLLGQPIFPGDSGVDQLVEIIKVLGTPTREQIREMNPNYTEFKFPQIKAHPWTKVSKQVFRPRTPPEAIALCSRLLEYTPTARLTPLEACAHSFFDELREP-NVKLPNGREKPSLFNFTTQELSSNPTLASILIPAHAR----------------------------------------------NQAGASTPTNPSATS-DANSG----DRSQTTTAAS---------------ASASNTST---------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "B8JIQ1-1", "uniprot_id": "B8JIQ1_DANRE", "id": "B8JIQ1-1", "name": "Glycogen synthase kinase-3 beta", "aln": "-------------------------MSGRPRTT------------------------SFAESCKPVPQ-----------------------------------------------------------PSAFGNMKVSRDKDGSKVTTVAATPGQGPDRPQEVSYTDTKVIGNGSFGVVYQAKLCDTGELVAIKKVLQDKRFKNRELQIMRKLDHCNIVRLRYFFYSSGDKKDEVYLNLVMDYVPENVYRVARHYSKAKQNLPMVYVKLYMYQLFRSLAYIHSYG-ICHRDIKPQNLLLDPETAVLKLCDFGSAKQLVRGEPNVSYICSRYYRAPELIFGATDYTSSIDIWSAGCVLAELLLGQPIFPGDSGVDQLVEIIKVLGTPTREQIREMNPNYTEFKFPQIKAHPWTKV----FRPRTPPEAIALCSRLLEYTPTARLTPLEACAHTFFDELREP-NLKLPNGRERPVLFNFTTQELSNNPSLASVLIPAHAQ----------------------------------------------NQAENSTQS-ASAAT-GANSG----DRGLNTNAAS---------------AAPNPST----------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P18431-2", "uniprot_id": "SGG_DROME", "id": "P18431-2", "name": "Protein kinase shaggy", "aln": "-------------------------MSGRPRTS------------------------SFAEGNKQSP------------------------------------------------------------SLVLGGVKTCS-RDGSKITTVVATPGQGTDRVQEVSYTDTKVIGNGSFGVVFQAKLCDTGELVAIKKVLQDRRFKNRELQIMRKLEHCNIVKLLYFFYSSGEKRDEVFLNLVLEYIPETVYKVARQYAKTKQTIPINFIRLYMYQLFRSLAYIHSLG-ICHRDIKPQNLLLDPETAVLKLCDFGSAKQLLHGEPNVSYICSRYYRAPELIFGAINYTTKIDVWSAGCVLAELLLGQPIFPGDSGVDQLVEVIKVLGTPTREQIREMNPNYTEFKFPQIKSHPWQKV----FRIRTPTEAINLVSLLLEYTPSARITPLKACAHPFFDELRMEGNHTLPNGRDMPPLFNFTEHELSIQPSLVPQLLPKHLQNASGPGGNRPSAGGAASIAASGSTSVSSTGSGASVEGSAQPQSQGTAAAAGSGSGGATAGTGGASAG----GPGSGNNSSS---------------GGASGAPSAVAAGGANAAVAGGAGGGGGAGAATAAATATGAIGATNAGGANVTDS----", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P83101-1", "uniprot_id": "GSK3H_DROME", "id": "P83101-1", "name": "Putative glycogen synthase kinase-3 homolog", "aln": "-------------------------MASQSKNS------------------------GLTN----------------------------------------------------------------------------------KVTTVVATNAFGADVMSEISYTDAKVVGNGSFGVVFQAKMVPSNEMVAIKKVLQDRRFKNRELQIMRKLRHDNIITLKWFFFSSGEKRDEVYLNLVMEFLPETLYKVERQYARAKQTLPVNFVRLYMYQLLRSMGYLHSLG-FCHRDIKPQNMLLDSETGVLKLCDFGSAKQLISGEPNVSYICSRYYRAPELIFGSTDYTTKIDMWSAGCVMSELLLGQLIFPGDSGVDQIVEIVKVMGTPTSEQLHDMNPHYKQFKLPELKPHPWSKV----FRIRTPAEAIDLVSKMLIYSPNARVSPLMGCAHPFFDELRQDPHQQLPNGRSLPPLFNFTDYEKTIEPDTMPLLLPRAQG---------------SSTTKEPSAAHRNRNTAGEESPRKTEDSQKPATAALSKSPGPSGKALESPPGFLQHDLGNGDHVAVGTMPMEPLTLEQNHFAAESYAVGEDAEDNLEEDVGDENDYDYDDGGQCNSTYISDDMDEASESDDDDFEEEDEN", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P50873-1", "uniprot_id": "MRK1_YEAST", "id": "P50873-1", "name": "Serine/threonine-protein kinase MRK1", "aln": "MTDVLRSLVRKISFNNSDNLQLKHKTSIQSNTALEKKKRKPDTIKKVSDVQVHHTVPNFNNSSEYINDIENLIISKLIDGGKEGIAVDHIEHANISDSKTDGKVANKHENISSKLSKEKVEKMINFDYRYIKTKERTIHKRVYKHDRKTDVDRKNHGGTIDISYPTTEVVGHGSFGVVVTTVIIETNQKVAIKKVLQDRRYKNRELETMKMLCHPNTVGLQYYFYEK-DEEDEVYLNLVLDYMPQSLYQRLRHFVNLKMQMPRVEIKFYAYQLFKALNYLHNVPRICHRDIKPQNLLVDPTTFSFKICDFGSAKCLKPDQPNVSYICSRYYRAPELMFGATNYSNQVDVWSSACVIAELLLGKPLFSGESGIDQLVEIIKIMGIPTKDEISGMNPNYEDHVFPNIKPITLAEI----FKAEDP-DTLDLLTKTLKYHPCERLVPLQCLLSSYFDETKRC------DTDTYVKAQNLRIFDFDVETELGHVPLVERPA----------------------------------------------IEERLKHFVSAPSSSL---------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P38615-1", "uniprot_id": "RIM11_YEAST", "id": "P38615-1", "name": "Serine/threonine-protein kinase RIM11/MSD1", "aln": "-------------------------MNIQSNNS-----------------------PNLSNN--------------------------------------------------------------------------IVSKQVYYAHPPPTIDPNDP---VQISFPTTEVVGHGSFGVVFATVIQETNEKVAIKKVLQDKRFKNRELEIMKMLSHINIIDLKYFFYER-DSQDEIYLNLILEYMPQSLYQRLRHFVHQRTPMSRLEIKYYMFQLFKSLNYLHHFANVCHRDIKPQNLLVDPETWSLKLCDFGSAKQLKPTEPNVSYICSRYYRAPELIFGATNYTNQIDIWSSGCVMAELLLGQPMFPGESGIDQLVEIIKILGTPSKQEICSMNPNYMEHKFPQIKPIPLSRV----FKKEDD-QTVEFLADVLKYDPLERFNALQCLCSPYFDELKLD------DGKINQITTDLKLLEFDENVELGHLSPDELSS----------------------------------------------VKKKLY-----PKSK----------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :...: .: : . ::*:. ::*:*:****** : : :.: *********:*:*****: *: * * * : * ::*:. :..**::***:::::*:.:*: *:: . : :. :: * :**:::: *:* .*********:*:*. * :*:******* * :****************:**: :*:..:*:**:.**::*****: :*.*:**:**:**::*::* *: ::: ***:* :. :*::*. . .: *: . ::: : : * * * *. .* .:*** : : :: : : . ", "identical_positions": 119, "similar_positions": 120, "identity": "18.25%" }, { "cls_id": "homologset.agr.MGI:1861438", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZXW4-1", "uniprot_id": "D3ZXW4_RAT", "id": "D3ZXW4-1", "name": "", "aln": "-------------MPADSMQDPDPVLSYGMKLTWDINDPQMPQEPAHFDHFREWPDGYVRFIYSSQEKKAQRHLSGWAMRNTNNHNGHILKKSCLGVVVCARACALKDGSHLQLRPAICDKARLKQQKKACPN--CHSALELVPCRGHSGYPVTNFWRLDGNAIFFQAKGVHDHPRPESKSETEGRRSALKRQMASFYQPQKRRSEEPEAGSTQDTRGHSNSTPVPEPSELFAMPADTSFPISGHSSLSFPNSDVHRVTCDLPTFPGDVILPFQKYSNPSIYFPGPPWSYELASPGVTGSSPYPTLYKDPSIVPDDPDWIHLNSLQYNVSSYG---SYERSLDLTARYHGWKPTHGKAGLEEKVDCRPCQAVPTSPYYNLELPCRYLPVAPAGTQALQTVITTT--VAYQAYQHPALKHGDSVQEVSSLASCTYASENLPMPIYPQALDPQEGAIQAASPSGRAPGIVPGDCQAARPTLAFPQETDPSRTAGADVWDVCLSGVGSVMAYLDRTGQPFNLDNEDF-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O09102-1", "uniprot_id": "GCM2_MOUSE", "id": "O09102-1", "name": "Chorion-specific transcription factor GCMb", "aln": "-------------MPADSTQDEDAVLSYGMKLTWDINDPQMPQEPTHFDHFREWPDGYVRFIYSSQEKKAQRHLSGWAMRNTNNHNGHILKKSCLGVVVCARACALKDGSHLQLRPAICDKARLKQQKKACPN--CHSPLELVPCRGHSGYPVTNFWRLDGNAIFFQAKGVHDHPRPESKSETEGRRSALKRQMASFYQPQKRRSEEPEARSTQDIRGHLNSTAALEPTELFDMTADTSFPIPGQPSPSFPNSDVHRVTCDLPTFQGDIILPFQKYPNPSIYFPGPPWGYELASSGVTGSSPYSTLYKDSSVVPDDPDWIPLNSLQYNVSSYG---SYERTLDFTARYHSWKPTHGKPSLEEKVDCEQCQAVPTSPYYNLELPCRYLPVPAAGTQALQTVITTT--VAYQAYQHPALKHSDSMQEVSSLASCTYASENLPMPIYPPALDPQEGVIQAASPSGRAPLKVPGDCQAPRPTLDFPQEADPSGTDGADVWDVCLSGVGSVMGYLDRTGQPFSFDNEDF-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O75603-1", "uniprot_id": "GCM2_HUMAN", "id": "O75603-1", "name": "Chorion-specific transcription factor GCMb", "aln": "-------------MPAAAVQEAVGVCSYGMQLSWDINDPQMPQELALFDQFREWPDGYVRFIYSSDEKKAQRHLSGWAMRNTNNHNGHILKKSCLGVVVCTQACTLPDGSRLQLRPAICDKARLKQQKKACPN--CHSALELIPCRGHSGYPVTNFWRLDGNAIFFQAKGVHDHPRPESKSETEARRSAIKRQMASFYQPQKKRIRESEAEENQDSSGHFSNIPPLENPEDFDIVTETSFPIPGQPCPSFPKSDVYKATCDLATFQGDKMPPFQKYSSPRIYLPRPPCSYELANPGYTNSSPYPTLYKDSTSIPNDTDWVHLNTLQCNVNSYS---SYERSFDFTNKQHGWKPALGKPSLVERTNHGQFQAMATRPYYNPELPCRYLTTPPPGAPALQTVITTTTKVSYQAYQPPAMKYSDSVREVKSLSSCNYAPEDTGMSVYPEPWGPPVTVTRAASPSGPPPMKIAGDCRAIRPTVAIPHEPVSSRTDEAETWDVCLSGLGSAVSYSDRVGPFFTYNNEDF-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q27403-1", "uniprot_id": "GCM_DROME", "id": "Q27403-1", "name": "Transcription factor glial cells missing", "aln": "MVLNGMPITMPVPMPVPMPVPSPPATKSRVAIDWDINDSKMP-SVGEFDDFNDWSNGHCRLIYSVQSDEARKHASGWAMRNTNNHNVNILKKSCLGVLLCSAKCKLPNGASVHLRPAICDKARRKQQGKQCPNRNCNGRLEIQACRGHCGYPVTHFWRRDGNGIYFQAKGTHDHPRPEAKGSTEARR--------LLAGGRRVRSLAVMLARESALSDKLSSLRPTKRQAKTQSIQESKRRRMG-------ASDVLETKQELVVPPTTYLP--TSTPTHSTNFNQSQGSYVPAGQGSVISQWNREIHYETEDPCYANGMYSYDMLHSPLSAHSSTGSYYQENKPQQLQHSQYQQQLSPQQHVPVSYDPSQPISSSLQCGMPS---YEICDDTSSLTSSSGYCSEDYGYYNGYLPNSLDVSNGSQSQNLSQDASFYTTSSEIFSVFESTLNGGGTSGVDLIYDEATAYQQHQQQGTFPHLTNYQQEPQDQMQSADYYYSNTGVDNSWNIQMDATYHPVNSTDPIYC", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " **. . . : : *****.:** . **.*.:*.:*: *:*** :..:*::* ************ :*********::*: * * :*: ::********** *** * *** *:. **: .****.*****:*** ***.*:*****.*******:*..**.** : :: * . .: .. : ::. * *** ... :* . : . .. : . .* *. * . *. :: :. . : *: :.::. ** : . *. .. .. *.:.: . * ..: : .: : *:.* ::. .:. :. . ...: . . : . . . . .. : :. * : :: . *: : . .* * . .. : : ", "identical_positions": 120, "similar_positions": 140, "identity": "22.86%" }, { "cls_id": "homologset.agr.MGI:1861440", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9WV59-1", "uniprot_id": "TRI17_RAT", "id": "Q9WV59-1", "name": "E3 ubiquitin-protein ligase TRIM17", "aln": "--------------------------------------------------------------------------MDAVELARRLQEEATCSICLDYFTDPVMTACGHNFCRECIQMSWEKGKGKKGKKKQKGSFPCPECREMSPQRNLRPNRLLTKVAEMARQHPG------------LHKRDLCQIHQEPLKLFCQDDQTPICVVCREAQEHRMHRVLPLDEAAREYKLRLEEDIKYLREEMMKTETLQAKEEQTLTEWQERVKERRERILEEFQKVVLFLVEEERRLLQILKKEEDDTLGKLQDSKASLDHQSRSLDLILLQLEEQT-QQEPLQMLQDVKDTLTRKESLSMQYPEVVLPVAIKTVCRVPGQIEVLKSFQEDVVPDP-------STAYPYLLLYESRQRRYLSPPPEGSAPYSKDRFLAYPCAVGQKSFSSGRHYWEVGMNLTGDALWALGVCRDNVSRKDRVLKSPENGFWVVQLSKGKKHLPLLPNSIPVTLTEPPSHMGIFLDFQAGEVSFYSVNDGSHLHSFSQVAFPGPLLPFFCLGSPKSGQMVISTVTMWVKG", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q7TPM3-1", "uniprot_id": "TRI17_MOUSE", "id": "Q7TPM3-1", "name": "E3 ubiquitin-protein ligase TRIM17", "aln": "--------------------------------------------------------------------------MDAVELARRLQEEATCSICLDYFTDPVMTACGHNFCRECIQMSWEKGKVKKGKKKQKGSFPCPECREMSPQRNLRPNRLLTKVAEMARQHPG------------LQKRDLCQAHQEPLKLFCQDDQSPICVVCREAQEHRMHRVLPLDEAAREYKLKLEEDIKYLREEMMKTETLQAKEEQTLTEWQERVKERRERILEEFQKVVLFLVEEERRILQVLKKEEEDTLGKLQDSKASLDHQSRSLDLILLQLEERS-QQEPLQMLQDVKDTLNRKESFSVQYPEVVLPAAIKTLCRVPGQIEVLKSFQEDVMPDP-------SSAYPYLLLYESRQRRYLSPPPEGSAPYSKDRFVAYPCAVGQKSFSSGRHYWEVGMNLTGDALWALGVCRDNVSRKDRVLKSPENGFWVVQLSKGKKQLSLLPNSTLVTLTEPPSHMGIFLDFQAGEVSFYSVNDGSHLHSFSQAAFPGPLLPFFCLGAPKSGQMVISTVTMWVKG", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9Y577-1", "uniprot_id": "TRI17_HUMAN", "id": "Q9Y577-1", "name": "E3 ubiquitin-protein ligase TRIM17", "aln": "--------------------------------------------------------------------------MEAVELARKLQEEATCSICLDYFTDPVMTTCGHNFCRACIQLSWEKARGKKGRRKRKGSFPCPECREMSPQRNLLPNRLLTKVAEMAQQHPG------------LQKQDLCQEHHEPLKLFCQKDQSPICVVCRESREHRLHRVLPAEEAVQGYKLKLEEDMEYLREQITRTGNLQAREEQSLAEWQGKVKERRERIVLEFEKMNLYLVEEEQRLLQALETEEEETASRLRESVACLDRQGHSLELLLLQLEERS-TQGPLQMLQDMKEPLSRKNNVSVQCPEVAPPTRPRTVCRVPGQIEVLRGFLEDVVPDA-------TSAYPYLLLYESRQRRYLGSSPEGSGFCSKDRFVAYPCAVGQTAFSSGRHYWEVGMNITGDALWALGVCRDNVSRKDRVPKCPENGFWVVQLSKGTKYLSTFSALTPVMLMEPPSHMGIFLDFEAGEVSFYSVSDGSHLHTYSQATFPGPLQPFFCLGAPKSGQMVISTVTMWVKG", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AC58GIM4-1", "uniprot_id": "A0AC58GIM4_DANRE", "id": "A0AC58GIM4-1", "name": "", "aln": "MRRHVQTSLTKSDVMRETPANFQQDQNPETPPILSPSQQESQSRRARRTEQSMSSSLPAQNKMDKQKLRPEIPPRVSKSSAQRLSRDLTCSICLDLFKQPVSLPCDHTFCEACITSYWSGPR----VKCQAGSGSCPQCRKVFHGKSYRPNRIVANIVESYCQGMEESGVRLGAVSEPAPTAPLCMRHREELKLYCEEDQELVCLVCGISQDHRAHTLVCVQDAQKRYRASLTTSANALQKELNTALECERETEEEVKKLKDHTADLKQRIEAQFSELHQFLYQEEKLLQVKLKTEERRELIRLDEHKALLSVEISRLRRAVNDIEDKLSEQDPYTLLRSIKGLLQRQ-PPKFERPTLTPPSLCEGRFAGPLQYRVWKSLKGSIYPVPSAITFNSKTANPWLSLTSSLTCVRYQTFN-SSVQDNPQRFNAALSLMGGQGFTKGRHYWEVEVYSS--TVWTVGVARESVTRKGVINTMPANGFWTLSLSYGVQYMAGTSPPTLLSLEEPLARIGVYLDYKRGLVSFYNAESMTHLYTFR-DTFTETLFPYFNLGFLDKVHENEPLKVFMPKI", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . *::*..: ******* *.:** .*.*.**. ** *. : : : ** .**:**:: :. ***:::::.* * . ** *:* ***:*:.** :*:** :::** * :: ::* : *: * . : *:::: : : . *: : : : :. : ::** :*.:: :* :**: : *:.** :* : * *. : * : ::*:: * * :*:.:* * *: ..: * :. * . * * .* :.: .: * . .:* *:* * .* . .* . :** * . :* .*:.******* : : ::*::**.*:.*:**. : . * ****.:.** * : :. . : * ** :::*::**:: * ****.... :**::: :*. .* *:* ** .. : . .: * ", "identical_positions": 130, "similar_positions": 159, "identity": "22.77%" }, { "cls_id": "homologset.agr.MGI:1861441", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P23640-1", "uniprot_id": "RB27A_RAT", "id": "P23640-1", "name": "Ras-related protein Rab-27A", "aln": "MSDGDYD--------YLIKFLALGDSGVGKTSVLYQYTDGKFNSKFITTVGIDFREKRVVYRANGPDGTVGRGQRIHLQLWDTAGQERFRSLTTAFFRDAMGFLLLFDLTNEQSFLNVRNWISQLQMHAYCENPDIVLCGNKSDLEDQRAVKEEEARELAEKYGIPYFETSAANGTNISQAIEMLLDLIMKRMERCVDKSWIPEGVVRS-------NGHTS-----TDQLSEEKEKGLCG-C", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9ERI2-1", "uniprot_id": "RB27A_MOUSE", "id": "Q9ERI2-1", "name": "Ras-related protein Rab-27A", "aln": "MSDGDYD--------YLIKFLALGDSGVGKTSVLYQYTDGKFNSKFITTVGIDFREKRVVYRANGPDGAVGRGQRIHLQLWDTAGQERFRSLTTAFFRDAMGFLLLFDLTNEQSFLNVRNWISQLQMHAYCENPDIVLCGNKSDLEDQRAVKEEEARELAEKYGIPYFETSAANGTNISHAIEMLLDLIMKRMERCVDKSWIPEGVVRS-------NGHTS-----ADQLSEEKEKGLCG-C", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P51159-1", "uniprot_id": "RB27A_HUMAN", "id": "P51159-1", "name": "Ras-related protein Rab-27A", "aln": "MSDGDYD--------YLIKFLALGDSGVGKTSVLYQYTDGKFNSKFITTVGIDFREKRVVYRASGPDGATGRGQRIHLQLWDTAGQERFRSLTTAFFRDAMGFLLLFDLTNEQSFLNVRNWISQLQMHAYCENPDIVLCGNKSDLEDQRVVKEEEAIALAEKYGIPYFETSAANGTNISQAIEMLLDLIMKRMERCVDKSWIPEGVVRS-------NGHAS-----TDQLSEEKEKGACG-C", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "O76901-1", "uniprot_id": "O76901_DROME", "id": "O76901-1", "name": "", "aln": "MRAAPPEPEPLQLAGSGEQFLVLGDSGVGKTCLLYQYTDGRFHTQFISTVGIDFREKRLLYNSRG------RRHRIHLQIWDTAGQERFRSLTTAFYRDAMGFLLIFDLTSEKSFLETANWLSQLRTHAYSEDPDVVLCGNKCDLLQLRVVSRDQVAALCRRYRLPYIETSACTGANVKEAVELLVGRVMERIENAACNREFSLLLTQSRCLPNIAYGQPEDLVRLHDRREEPCSRRNCRNC", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* . : :**.*********.:*******:*:::**:**********::*.: * * :*****:****************:********:****.*:***:. **:***: ***.*:**:******.** : *.*..::. *..:* :**:****..*:*:..*:*:*:. :*:*:*... : :. :.:* *:.. *: .* .: * *", "identical_positions": 115, "similar_positions": 70, "identity": "47.52%" }, { "cls_id": "homologset.agr.MGI:1861444", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9JKL9-1", "uniprot_id": "PR2B1_RAT", "id": "Q9JKL9-1", "name": "Prolactin-2B1", "aln": "MLLYLPQIFSSRASSLLFLVPYLLFWENVASISTCAERDATIQHSLEKLLTLTTFMSHVMSIETAKLFTEFNNQYAQGKRYNDRIPGTCHTAFFDTPVNKEQSLGSDPKTLLKLVRSLLNSWTNALNHLVNEISAMQGDPSFLFSKAREIQAKFDELTTGVKTILSMIGERDNDTHLAWSGLSSLQSSNEDVRCFSFYTLIRCLLRDSRKVNTYLEVIKYQIFNQNNC", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9DAZ2-1", "uniprot_id": "PR2B1_MOUSE", "id": "Q9DAZ2-1", "name": "Prolactin-2B1", "aln": "MLLSLTQMLSSRASSRLFLVSYLLLWENVVSTSTCAEKDATIQDSLEKLLTLTTFMSQVVSSETAKLFTEFNNQYAQGKRYNDRIPGTCHTEFFDTPVNKEQSLVRTPETLLTLVHSLLNSWTNALNHLVNEMSTMQGDTSSLISKAREIQAKFDELTTGVKIVQSMIGERDIATYSAWSGLASLQSSNEDVRCFSFYTMIRCLLRDSRKVNTYLEVIKYKMVDQNNC", "tax_id": 10090, "tax_name": "Mouse" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*** *.*::****** ****.***:****.* *****:*****.*************:*:* ***************************** ************ *:***.**:****************:*:****.* *:****************** : ******* *: *****:****************:********************::.:****", "identical_positions": 189, "similar_positions": 25, "identity": "82.89%" }, { "cls_id": "homologset.agr.MGI:1861446", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9JII3-1", "uniprot_id": "PR2A1_RAT", "id": "Q9JII3-1", "name": "Prolactin-2A1", "aln": "MQLSITHPCCWTLRLLLVSNLLLWENVALVPTCLVRNGRCFASLEEMLERAVGLSEEISKQALQLFTEFDNQYAQSKQLINKNFKKCHTSSLELPKPSSTSVQTHPITLLKIASKLLSAWKVPLNDLVNNLPSLKDIHPNILSKAREIEAKSAGLLEGVKSILIQMQNGDTEDENYPGWSGLASLQSENEDDRLFAYYNMIRCEGRETQKVETALKMVKCKISNENNC", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9JHK0-1", "uniprot_id": "PR2A1_MOUSE", "id": "Q9JHK0-1", "name": "Prolactin-2A1", "aln": "MQLSVTHPCCRTLILLLVSNLLLWESEAVLPICSVRNGRCFGSFEELLERAVSLSEEISKKAFELFTAFDSQYAQSHQLIVKSLKKCHTSSLDLPKPGSQAMQTHPVTLLKLASKLLRAWQVPLNHLVNNLPSLKNVSPSILSKAKEIEEKSNGLLEGVKSILIQMQNGDTEDENYPGWSGLASLKSETEDIRLFAYYNMIRCEGRDTQKVETALKMVKCKISNENNC", "tax_id": 10090, "tax_name": "Mouse" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "****:***** ** ***********. *::* * *******.*:**:*****.*******:*::*** **.*****:*** *.:********:****.* ::****:****:***** **:****.*********:: *.*****:*** ** ********************************:**.** **************:*********************", "identical_positions": 185, "similar_positions": 30, "identity": "81.14%" }, { "cls_id": "homologset.agr.MGI:1861447", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9WV06-1", "uniprot_id": "ANKR2_MOUSE", "id": "Q9WV06-1", "name": "Ankyrin repeat domain-containing protein 2", "aln": "-------------------------------MEGPEAVQRATELIEQRLAQEEETEKLRRSAPGKLSMDMLVLEEEKRLGVQSPALQKVKGQERVRKTSLDLRREIIDVGGIQNLIELRKKRKQKKRDALAAAQEPPPEPEEITGPVNEETFLKAAVEGKMKVIDKYLADGGSADTCDEFRRTALHRASLEGHMEILEKLLENGATVDFQDRLDCTAMHWACRGGHLEVVRLLQSRGADTNVRDKLLSTPLHVAVRTGHVEIVEHFLSLGLDINAKDREGDSALHDAVRLNRYKIIKLLLLHGADMMAKNLAGKTPTDLVQLWQADTRHALEHPEPESEQNGLERPG-SGRETPQPIPAQ", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8I6A2R5-1", "uniprot_id": "A0A8I6A2R5_RAT", "id": "A0A8I6A2R5-1", "name": "Ankyrin repeat domain-containing protein 2", "aln": "---------------------------MEGTMEGPEAVQRATELIEQRLAEEEETEKLRRATPGKTSMDMLVLEDEKRLGVQSPALQKVKGQERVRKTSLDLRREIIDVGGIQNLIELRKKRKQKKRDALAAAQEPPPEPEEITGPVDEETFLKAAVEGKIKVIDKYLADGGSADTCDEFRRTALHRASLEGHMEILEKLLENGATVDFQDRLDCTAMHWACRGGHLEVVKLLQSRGANTDVRDKLLSTPLHVAVRTGHVEIVEHFLSLGLDINAKDREGDSALHDAVRLNRYKIIKLLLLHGADMMAKNMAGKTPTDLVQLWQADTRHALEHPEPESEQNGLERPG-SGRETPQPVPAQ", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9GZV1-1", "uniprot_id": "ANKR2_HUMAN", "id": "Q9GZV1-1", "name": "Ankyrin repeat domain-containing protein 2", "aln": "MAKAPSWAGVGALAYKAPEALWPAEAVMDGTMEDSEAVQRATALIEQRLAQEEENEKLRGDARQKLPMDLLVLEDEKHHGAQSAALQKVKGQERVRKTSLDLRREIIDVGGIQNLIELRKKRKQKKRDALAASHEPPPEPEEITGPVDEETFLKAAVEGKMKVIEKFLADGGSADTCDQFRRTALHRASLEGHMEILEKLLDNGATVDFQDRLDCTAMHWACRGGHLEVVKLLQSHGADTNVRDKLLSTPLHVAVRTGQVEIVEHFLSLGLEINARDREGDTALHDAVRLNRYKIIKLLLLHGADMMTKNLAGKTPTDLVQLWQADTRHALEHPEPGAEHNGLEGPNDSGRETPQPVPAQ", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " **..******* *******:***.**** : * .**:****:**: *.**.************************************************::*************:************:***:*:***********:**********************:****************************:****:**:*:*****************:************:***:*****:*************************:**:************************* :*:**** *. ********:***", "identical_positions": 286, "similar_positions": 33, "identity": "79.44%" }, { "cls_id": "homologset.agr.MGI:1861452", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9JJI6-1", "uniprot_id": "PIGO_MOUSE", "id": "Q9JJI6-1", "name": "GPI ethanolamine phosphate transferase 3, catalytic subunit", "aln": "-----------------------------MRKVSVLLFLAWVCFLFYAGIALFTSGFLLTRLELTNQSSCQEL----------PGPGPLPWGSHGKPGACWMPSRFSRVVLVLIDALRFDFAQPQRSHVPGEPPVSVPFLG-KLGSLQRILESQPHHGRLYRSQVDPPTTTMQRLKALTTGSLPTFIDAGSNFASHAIVEDNVIQQLNSAGRRVVFMGDDTWRDLFPGAFS-QAFFFSSFNVRDLHTVDNGILEHLYPTLDGG-SWDVLIAHFLGVDHCGHKHGPHHPEMAKKLSQMDQVIQGLIERLENDTLLVVAGDHGMTMNGDHGGDSELEVSAALFLYSP---------TALFPSVPP-EEPEVIPQVSLVPTLALLLGLPIPFGNTGEVMAELFSGGS---------DSSHPHSSALAQVSALHINAQQVSRFLHTYSAATQDLQ-VKELHRLQTLFSKASARYQHFLRDPQEAEAALSTLTAEFQQFLRGARALCIESWARFSLVRMAGGAALLAAACLLCLLAS------QLAVAPGFLFRPLLLIPVAWGLTWT--ILYAGVSVTTGSKIDLVVLGAVAAAGSLLPFLWKAWVSRGSKRPLAPLLPVP--RPVLILLLIRLATFFSDSFFVVEARATPFLLGSLVFFLVAQLHWEGQLLP---PKPLTMSRLGSSAPTAPPRHSGAHALWLGIGLLLFTRLAGL-FHRCPEETPACRSSPWLSPLASMVGGRAKNLWYGACVGALVALLVVVRLWLRRYGNLKSPEPPVLFVRWGMPLMVLGTAAYWALASGAEEAPPRLRALVAGASAVLPRAVMGLAALGLVLLLWRPVTVLVKAGAATSRTRTILTP----FSGPPTSQADLDYVVPQIYRHMQEEFQ-GRLERTKAQGPITVAAYQLGSVYSAAMVTALLLLAFPLMLLHVERVSLVFLLLFLQSFLLLHLLAAGTPVATP----GPFTVLWQAVSAWVLLATQTFYSTGHQPVFSAIHWHAAFVGFPDGHGSSTWLPALLVGANTFASHLLFAVGCPLL-----LLWPFLCERQGPKRRQPLPGSESEARVRPEEEEELQEPLMEVRLRDAPNHFNAALLQLGLKYLFILGAQILACALAASILRRHLMVWKVFAPKFIFEAVGFIVSSVGLLLGIALVMRVDVAVSSWFKKLVLAQQR", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0ABK0LN10-1", "uniprot_id": "A0ABK0LN10_RAT", "id": "A0ABK0LN10-1", "name": "GPI ethanolamine phosphate transferase 3, catalytic subunit", "aln": "--------MHTSVVPDCKHCRRTSGRESRMQKISVLLFLAWVCFLFYAGIALFTSGFLLTRLELTNQSSCQEP----------PGPGSLPWGSQGKPGACWMPSRFSRVVLVLIDALRFDFAQPQCSHVPGEPPVSVPFLG-KLGSLKRILEVQPHHARLYQSQVDPPTTTMQRLKALTTGSLPTFIDAGSNFASHAIVEDNLIKQLTSAGKRVVFMGDDTWKDLFPGAFS-QAFFFSSFNVRDLHTVDNGILEHLYPTMDSG-AWDVLIAHFLGVDHCGHKHGPHHPEMAKKLSQMDQVIQGLIERLENDTLLVVAGDHGMTMNGDHGGDSELEVSAALFLYSP---------TVLFPSVPP-EEPEVIPQISLVPTLALLLGLPIPFGNIGEVMAELFSGGSGGGSSRGDGDASHPDSPALAQVSALYINAQQVSRFLHTYSAATQDLH-VKELRRLQELFSKASARYQHLLQHPREAEAALSSLTADFQQFLRGARAVCIESWARFSLVRMAGGAALLAAACLLCLLAS------QLAVAPGFLFRPLLLIPVAWGLTWT--LLYAGVSVTTGSKLDPVVLGAVAAAGSLLPFLWKAWLSWGSKRPLAPLLPVP--RPVLALLLIRLATFFSDSFVVAEARATPFLLGSLILFLVAQLHWEGQLLP---PKLLTTSRLGSSAPTAPPRHSGTHALLLGIGLLLFTRLAGL-FHRCPEETPACRSSPWLSPLASMVGGRAKNLWYGACVGALVALLAAVRLWLRRYGNLKSPEPPVLFVRWGLPLMVLGTAAYWALASGAEEVPPRLRALVAGASAVLPRAVMGLAASGLMLLLWRPVTVLVKAGAATSRTRTILTP----FSGPPTSQADLDYVVPQIYRHMQEEFQ-GRLERTRAQGPITVAAYQLGSVYSAAMVTALILLAFPLLLLHVERVSLVFLLLFLQSFLLLHLLAAGTPVATP----GPFTVMWQAVSAWVLLATQTFYSTGHQPVFSAIHWHAAFVGFPDGHGSSTWLPALLVGANTFASHLLFAVGCPLL-----LLWPFLCERQGPKKRQSLPGSESEARVRPEEEQ--EEPLMEMRLRDAPHHFNAALLQLGLKYLFVLGAQILACALAASILRRHLMVWKVFAPKFIFEAIGFIVSSVGLLLGIALVMRVDGAVSSWFKKLVLAQQR", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8TEQ8-1", "uniprot_id": "PIGO_HUMAN", "id": "Q8TEQ8-1", "name": "GPI ethanolamine phosphate transferase 3, catalytic subunit", "aln": "-----------------------------MQKASVLLFLAWVCFLFYAGIALFTSGFLLTRLELTNHSSCQEP----------PGPGSLPWGSQGKPGACWMASRFSRVVLVLIDALRFDFAQPQHSHVPREPPVSLPFLG-KLSSLQRILEIQPHHARLYRSQVDPPTTTMQRLKALTTGSLPTFIDAGSNFASHAIVEDNLIKQLTSAGRRVVFMGDDTWKDLFPGAFS-KAFFFPSFNVRDLDTVDNGILEHLYPTMDSG-EWDVLIAHFLGVDHCGHKHGPHHPEMAKKLSQMDQVIQGLVERLENDTLLVVAGDHGMTTNGDHGGDSELEVSAALFLYSP---------TAVFPSTPP-EEPEVIPQVSLVPTLALLLGLPIPFGNIGEVMAELFSGGE----------DSQPHSSALAQASALHLNAQQVSRFLHTYSAATQDLQ-AKELHQLQNLFSKASADYQWLLQSPKGAEATLPTVIAELQQFLRGARAMCIESWARFSLVRMAGGTALLAASCFICLLAS------QWAISPGFPFCPLLLTPVAWGLVGA--IAYAGLLGTIELKLDLVLLGAVAAVSSFLPFLWKAWAGWGSKRPLATLFPIP--GPVLLLLLFRLAVFFSDSFVVAEARATPFLLGSFILLLVVQLHWEGQLLP---PKLLTMPRLGTSATTNPPRHNGAYALRLGIGLLLCTRLAGL-FHRCPEETPVCHSSPWLSPLASMVGGRAKNLWYGACVAALVALLAAVRLWLRRYGNLKSPEPPMLFVRWGLPLMALGTAAYWALASGADEAPPRLRVLVSGASMVLPRAVAGLAASGLALLLWKPVTVLVKAGAGAPRTRTVLTP----FSGPPTSQADLDYVVPQIYRHMQEEFR-GRLERTKSQGPLTVAAYQLGSVYSAAMVTALTLLAFPLLLLHAERISLVFLLLFLQSFLLLHLLAAGIPVTTP----GPFTVPWQAVSAWALMATQTFYSTGHQPVFPAIHWHAAFVGFPEGHGSCTWLPALLVGANTFASHLLFAVGCPLL-----LLWPFLCESQGLRKRQQPPGNEADARVRPEEEE---EPLMEMRLRDAPQHFYAALLQLGLKYLFILGIQILACALAASILRRHLMVWKVFAPKFIFEAVGFIVSSVGLLLGIALVMRVDGAVSSWFRQLFLAQQR", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "E9QI13-1", "uniprot_id": "E9QI13_DANRE", "id": "E9QI13-1", "name": "GPI ethanolamine phosphate transferase 3, catalytic subunit", "aln": "-----------------------------MRRLPILLALLWVCSVFYVGIFLFVGGFLLVRLEVNRMSTCADV----------LSP-----VAQLKGDFCLSEPRFRRAVVLIIDALKADFTRYD-----PENAAPKPFEN-KLPVLDEMASAHSSHARLYTFRADPPTTTMQRIKGFTTGSLPTFIDVGNNFASNAILEDNLVHQLGQVGKRVVFMGDDTWVSLFPKKFH-RSLPFPSFNVKDLHTVDNGILQNIYPTMEGD-DWDVLIAHFLGVDHCGHRFGPDHPAMAEKLSQMDGVIRSVIKRLKNDTLLVVMGDHGMTDTGDHGGESQKETDAALFLYSS---------SPLFPAPGSQVEPEVVPQTDLVPTLALLLGVPIPYSSVGQVLLPLFPQNG-----------SRGAPTGLSQAEALWINVKQVNRFLETYSNMAKDIP-PDSLSQLQADFSNISSQY---LSAVHKGHLPPLKLVISMQNYLTAVRETCRASWARFNPFKMAAGLLILAVSCVLCYALS------ELSCV--VVQEGLLKLPILSGLAVG--LVIAAGQLFLQGYLEFSWCLGTAALSSEVLFLWKTRR--VSQKCRWSLSGLL--TPALLVLFLRCASLLSDSYVIYEGHVVTFLLFTLSIYIPLRLNWDGLLVPLPPPDTQKPPRLLPTTLPSSVVRREASVLLVWLGVLVGSLYVSLSFHNCREEQGTCQPSSFLSPLSRVQDSQLRNLHYVLSVFSLATWGYLLHRWLRHYGNLNCSSLTVFTACFLIPLACVCIGLHWAVSATPEDTFRSLSELIGLAQVFLPRAAFCLLGLGLLLLWLDPMTVFLKTRTPLSSRGTSLPPPKYRASTGISPQAELHHLIPQLYQRIRHSLEDGSTDSGEVDNRPAVEAYGLGTVYSAPLVLLCGLLGLVLLLLHPEGMALAFLLLLLEAGAVLHIHACSTTLSSLHKHSNDFSVPWAPVVSWSLAAAQFFHASGHLPTFPSIQWGAAFVGFPQGH-TGNLLPASLVTLNTFASHIIFAVGCPLL-----LLWPLVCEVRG---------SRSTRSAGLEESE---DAVMEMRLRENPQNFSSCLLQLAARYLFVSGAQVFASVCAAAILRRHLMVWKVFAPKLMFEAFGFIVGSVFLILGVAMVMRVDLSVGGLFKKLLPQNSR", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A1ZB84-1", "uniprot_id": "A1ZB84_DROME", "id": "A1ZB84-1", "name": "GPI ethanolamine phosphate transferase 3, catalytic subunit", "aln": "------------------------------MNLTYLFVLIWLAFLISSGVMLFSRGFLLARVSKTETSTCRRLSTNPNAEYVLTDEVVNEIFKDVNASSNLCLPQKSKVIVLVVDALKYEFGLYR-----ANATDPLPYEN-KLVVLQELLQQNPDHARLMRFRADPPTTTLQRLKGLTTGSLPTFIDIGSNFASPEINEDNIIDQIVKNDLPVVFLGDSTWTDLYPHRFK-RSYSYPSFDIFDLDSVDNEILKHLPKELESK-DWQVLVAHFLGVDHCGHKHGPMHEEMARKLGEMNEVIRSVVAAMDNDTTLLVMGDHGMTASGDHGGDTDDETNALLFAYSK---------QHRFYGNDSGSDSEMLQQIDLVPTLATILGVPIPYSNLGLVNFNIVPDLR-----------VPHLNKFQTLLLHSWQNAQQIYRYFFQYALENKRTFNVEQMDHLETEFILLTHRVQ-----TVYNEVAFKSFVRDLNTNLRDILGTCREIWVRFDPTQMSQGLLFTFLPLFFIFLVVNNS---RPADFPHIFKAKEVFYVYLINLAAG--VFGYRYFKTFSFKTEEQGVIFFTAISSAVILAFHTLRHWTSIATNWSAVKRFGHMPTRLLLFGSMAVFFSNSFVIQEAKILSYLLAAAILLLSHELLRLSARLD-----------FRTKFKASQFLRSTALRLILASVLAICLIRFAYTLFRCREEQGNCSDFVNTGGAGFSLKKPGTGKTYILAVVVLVVYTTLTRLYLRSCGNLTGNLPNVLLARYGPTVASICAGGHILLAN------SSIKHIQRTHIDAMALVIYGLLLVQIIVLSWAPLMTFVLP--PRSSHTVTING--------------NESIVPEIFRKMKRMYE----GDDDERRSHIPVVYGLATVYSSIVIAFGVFLALVMIVLLEPRASIGLVVCVAVGAILLSVHSILRYRTATS-FESCVQPTFTALVGWFLLAHFCFFATSHQTTLSQIEWRAAFVGRTTGIGQSNLVSGALVILNTFCGPIFFFCMYSLLSTETFSLFALFPNLIRSCRSGGKVDASTSMSDLANEAVGFDMTRGELSLYEYEDVFLGTGFKLATQFFMLQGLKIFCAMLACTIHCRHLMVWKIFAPRFIYEALATFVSLPALIVGYLLVLRIHRGVDTLIKRINKAKVH", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q07830-1", "uniprot_id": "GPI13_YEAST", "id": "Q07830-1", "name": "GPI ethanolamine phosphate transferase 3", "aln": "MDEKTIKKSILSSSNDEKIIYKSRIKKFQKNHKFYIILLVFIAILQFISIAFFTRGFLLSRHVLDNISSQNET--------------------------SKLPPRFNKAVILVIDALRFDFAIPVN---ESHSNYNLNYHNNILSLYDSFASDKDASSLLLKFIADPPTTTLQRLKGLTTGSLPTFIDAGSNFDGTVIEEDNFLKQLHLANKTVKFAGDDTWMALFHPFLSNDSFPLESLNVWDLDTVDNGVMDYFHDHLQQDKEWDVMIGHMLGIDHVGHKYGPDHFTMREKQIQVDQFIDWILKSIDDDTLLVILGDHGMDHTGNHGGDSIDELESTLFLYSKKPDMWRLKETSNYNIDNLGHDYRSVRQIDLVSSLALLMGQPIPFNNLGWPIDEIARNDR-----------------EWSQFVNSAISQLQLYKDTMQIHHGN-----DEILEPLAKNISNTPPTSD------------PEKFVKLGHKYQKVFLQTCEELWAKFDYYSIATGITLLATSLVLLISITKLIPSIVVNQMVPEFVPGIIIMVLVTNLCFHGIFYVYQQPSFVDQFWGTLLATAIGIIIGCYITIFDRYNFIWIAMRLGETLADYWSRIAVMFMIIHALLFTSNSFTIWEDRIVAFLLSTFGMLTLYEFVFLPKRQS------------TTALLTATISEKEGTTSGVNPSTANSNYLPLTRFARLLGGYHSAVLIIFTRLASMITICREEQGEY--CIPTFNNQNNSSWWVLGLCFLMIFILPACITGYYNLTSSYQAAAPIWINVF--------LKGILGLNFVYWSLTSLENNSAVIAIPFLRDVTIFKFTLARIIAGFSLIAS-------------NVGWLMGPLCIKLNIHNT--------DVKSHEATILGYTNIYGSEFFLLVINVLISILLFNKPLAQLSYFLMCNQLLSILEIIDLLK-----------LKENIIGPIALGLLSYQHFFTTGHQATIPSVQWD---IGFMLSEKVTFPFTQIAIILNTFGPHILVSLSVALL-----TLWSQPPDVLK------------------------------------PQTLLGRIVSNCGILLTYNTILCLSSFIWVTHFRRHLMVWKIFCPRFIFASLSLIVTQLVVTFG-----TIAFASGRLIKHINDIFWK", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . :: * ::. : .: :* **** * . *: .: :.:::::***: :* . : . * . : . : . * .******:**:*.:********** *.** . * ***.:.*: . * * **.** *: : : *::: **.:*** ::. : :: *:*::.*:**:** **:.** * * .* ::: .* :: :.:** *:: ***** .*:***:: * .: ** ** : : . : * .**.:** ::* ***:.. * : : . *: : . : * : . .. : * *.:*. :: * : . .: : .* . . :. . .:: : *:*: : * : .:** : : .: . . . : : . . . * .: : * : : : . . : : . . : : : : . : :: : ::. .:*.: .. : : :::: : .: :* : . . * : *.::.* ..:. :.* :* . .. : *** ::. .** *:. : . : . .. : :.. : *******:*.*:::: :.. :* : .* : . . :::: :", "identical_positions": 134, "similar_positions": 242, "identity": "11.33%" }, { "cls_id": "homologset.agr.MGI:1861453", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9Z2N8-1", "uniprot_id": "ACL6A_MOUSE", "id": "Q9Z2N8-1", "name": "Actin-like protein 6A", "aln": "---MSGGVYGGDEVGALVFDIGSYTVRAGYAGEDCPKVDFPTAIGVVLERDDGSTMMEIDGDKGKQGGPTYYIDTNALRVPRENMEAISPLKN-GMVEDWDSFQAILDHTYKMHVKS-EASLHPVLMSEAPWNTR---AKREKLTELMFEHYSIPAFFLCKTAVLTAFANGRSTGLILDSGATHTTAIPVHDGYVLQQGIVKSPLAGDFITMQCRELFQEMNIELIPPYMIASKEAV-----REGSPANWKRKE--------------------------KLPQVTRSWHNYMCNCVIQDFQASVLQVSDSTY----------DEQVAAQMPTVHYEFPNGYNCDFGAERLKIPEGLFD------PSNVKG--------------------------------LSGNTMLGVSHVVTTSVGMCDIDIRPGLYGSVIVAGGNTLIQSFTDRLNRELSQKTPPSMRLKLIANNTTVERRFSSWIGGSILASLGTFQQ-MWISKQEYEEGGKQCVERKCP----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O96019-1", "uniprot_id": "ACL6A_HUMAN", "id": "O96019-1", "name": "Actin-like protein 6A", "aln": "---MSGGVYGGDEVGALVFDIGSYTVRAGYAGEDCPKVDFPTAIGMVVERDDGSTLMEIDGDKGKQGGPTYYIDTNALRVPRENMEAISPLKN-GMVEDWDSFQAILDHTYKMHVKS-EASLHPVLMSEAPWNTR---AKREKLTELMFEHYNIPAFFLCKTAVLTAFANGRSTGLILDSGATHTTAIPVHDGYVLQQGIVKSPLAGDFITMQCRELFQEMNIELVPPYMIASKEAV-----REGSPANWKRKE--------------------------KLPQVTRSWHNYMCNCVIQDFQASVLQVSDSTY----------DEQVAAQMPTVHYEFPNGYNCDFGAERLKIPEGLFD------PSNVKG--------------------------------LSGNTMLGVSHVVTTSVGMCDIDIRPGLYGSVIVAGGNTLIQSFTDRLNRELSQKTPPSMRLKLIANNTTVERRFSSWIGGSILASLGTFQQ-MWISKQEYEEGGKQCVERKCP----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P80428-1", "uniprot_id": "ARP4_YEAST", "id": "P80428-1", "name": "Actin-related protein 4", "aln": "MSNAALQVYGGDEVSAVVIDPGSYTTNIGYSGSDFPQSILPSVYGKYTADE----------------GNKKIFSEQSIGIPRKDYELKPIIEN-GLVIDWDTAQEQWQWALQNELYLNSNSGIPALLTEPVWNST---ENRKKSLEVLLEGMQFEACYLAPTSTCVSFAAGRPNCLVVDIGHDTCSVSPIVDGMTLSKSTRRNFIAGKFINHLIKKALEPK--EIIPLFAIKQRKPE-----FIKKTFDYEVDKSLYDYANNRGFFQECKETLCHICPTKTLEETKTELSSTAKRSIESPWNEEIVFDNETRYGFAEELFLPKEDDIPANWPRSNSGVVKTWRNDYVPLKRTKPSGVNKSDKKVTPTEEKEQEAVSKSTSPAANSADTPNETGKRPLEEEKPPKENNELIGLADLVYSSIMSSDVDLRATLAHNVVLTGGTSSIPGLSDRLMTELN-KILPSLKFRILTTGHTIERQYQSWLGGSILTSLGTFHQ-LWVGKKEYEEVGVERLLNDRFR---", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "Q12406-1", "uniprot_id": "ARP7_YEAST", "id": "Q12406-1", "name": "Actin-related protein 7", "aln": "---------MTLNRKCVVIHNGSHRTVAGFSNVELPQCIIPSSYIKRTDEG---------GEAEFIFGTYNMIDAAAE--KRNGDEVYTLVDSQGLPYNWDALEMQWRYLYDTQLKV-SPEELPLVITMPATNGKPDMAILERYYELAFDKLNVPVFQIVIEPLAIALSMGKSSAFVIDIGASGCNVTPIIDGIVVKNAVVRSKFGGDFLDFQVHERLAPLIKEENDMENMADEQKRSTDVWYEASTWIQQFKSTMLQVSEKDLFELERYYKEQADIYAKQQEQLKQMDQQLQYTALTGSPNNPLVQKKNFLFKP-------LNKTLTLDLKECYQFAEYLFKPQLISDKFSPEDGLGPLMAKSVKKAGASINSMKANTSTNPNGLG---------------TSHINTNVGDNNSTASSSNISPEQVYSLLLTNVIITGSTSLIEGMEQRIIKELS-IRFPQYKLTTFANQVMMDRKIQGWLGALTMANLPSWSLGKWYSKEDYETLKRDRKQSQATNATN", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : .:*:. **: . *::. : *: :*: * :. : *:. * . :.. *: :**: : . .: . . * ::: . * :: *: :: .. . : . ::: *:.. :::* * .. *: ** .:.:. :. :.*.*: :: : * : ..: .. : .. : . . .: : :: .: : :. :. : :. : . : . .*: . * :* . . :* . :: . * .*:::*..: * .: :*: **. *. :: ::. ::*: ..*:*. ::.* :: * .*::** : . ", "identical_positions": 44, "similar_positions": 149, "identity": "8.45%" }, { "cls_id": "homologset.agr.MGI:1861457", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P63167-1", "uniprot_id": "DYL1_HUMAN", "id": "P63167-1", "name": "Dynein light chain 1, cytoplasmic", "aln": "MCDRK---AVIKNADMSEEMQQDSVECATQALEKYNIEKDIAAHIKKEFDKKYNPTWHCIVGRNFGSYVTHETKHFIYFYLGQVAILLFKSG", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P63170-1", "uniprot_id": "DYL1_RAT", "id": "P63170-1", "name": "Dynein light chain 1, cytoplasmic", "aln": "MCDRK---AVIKNADMSEEMQQDSVECATQALEKYNIEKDIAAHIKKEFDKKYNPTWHCIVGRNFGSYVTHETKHFIYFYLGQVAILLFKSG", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P63168-1", "uniprot_id": "DYL1_MOUSE", "id": "P63168-1", "name": "Dynein light chain 1, cytoplasmic", "aln": "MCDRK---AVIKNADMSEEMQQDSVECATQALEKYNIEKDIAAHIKKEFDKKYNPTWHCIVGRNFGSYVTHETKHFIYFYLGQVAILLFKSG", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O96860-1", "uniprot_id": "DYL2_DROME", "id": "O96860-1", "name": "Dynein light chain 2, cytoplasmic", "aln": "MSDRK---AVIKNADMSEEMQQDAVDCATQALEKYNIEKDIAAFIKKEFDKKYNPTWHCIVGRNFGSYVTHETRHFIYFYLGQVAILLFKSG", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q02647-1", "uniprot_id": "DYL1_YEAST", "id": "Q02647-1", "name": "Dynein light chain 1, cytoplasmic", "aln": "MSDENKSTPIVKASDITDKLKEDILTISKDALDKYQLERDIAGTVKKQLDVKYGNTWHVIVGKNFGSYVTHEKGHFVYFYIGPLAFLVFKTA", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*.*.: .::* :*:::::::* : :.:**:**::*:***. :**::* **. *** ***:*********. **:***:* :*:*:**:.", "identical_positions": 43, "similar_positions": 36, "identity": "46.74%" }, { "cls_id": "homologset.agr.MGI:1861461", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q4ABE3-1", "uniprot_id": "Q4ABE3_DROME", "id": "Q4ABE3-1", "name": "", "aln": "MSDSAVATSASPVAAPPATVEKKVVQKKASGSAG-TKAKKASATPSHPPTQQMVDASIKNLKEHGGSSLLAIKKYITATY--KCDAQKLAPFIKKYLKSAVVNGKLIQTKGKGASGSFKLS-----ASAKK-EKDPKAKSKVLSAEKKVQSKKVASKKIGVSSKKTAVGAADKKPKAKKAVATKKTAENKKTEKAKAKDAKKTGIIKSKPAATKAKVTAAKPKAVVAKASKAKPAVSAKPKKTVKKASVSATAKKPKAKTTAAKK------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q4ABD8-1", "uniprot_id": "Q4ABD8_DROME", "id": "Q4ABD8-1", "name": "", "aln": "MSDSAVATSASPVAAPPATVEKKVVQKKASGSAG-TKAKKASATPSHPPTQQMVDASIKNLEERGGSSLLAIKKYITATY--KCDAQKLAPFIKKYLKSAVVNGKLIQTKGKGASGSFKLS-----ASAKK-EKDPKAKSKVLSAEKKVQSKKVASKKIGVSSKKTAVGAADKKPKAKKAVATKKTAENKKTEKAKAKDAKKTGIIKSKPAATKAKVTAAKPKAVVAKASKAKPAVSAKPKKTVKKASVSATAKKPKAKTTAAKK------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P02255-1", "uniprot_id": "H1_DROME", "id": "P02255-1", "name": "Histone H1", "aln": "MSDSAVATSASPVAAPPATVEKKVVQKKASGSAG-TKAKKASATPSHPPTQQMVDASIKNLKERGGSSLLAIKKYITATY--KCDAQKLAPFIKKYLKSAVVNGKLIQTKGKGASGSFKLS-----ASAKK-EKDPKAKSKVLSAEKKVQSKKVASKKIGVSSKKTAVGAADKKPKAKKAVATKKTAENKKTEKAKAKDAKKTGIIKSKPAATKAKVTAAKPKAVVAKASKAKPAVSAKPKKTVKKASVSATAKKPKAKTTAAKK------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q4AB54-1", "uniprot_id": "Q4AB54_DROME", "id": "Q4AB54-1", "name": "", "aln": "MSDSAVATSASPVAAPPATVEKKVVQKKASGSAG-TKAKKASATPSHPPTQQMVDASIKNLKERGGSSLLAIKKYITATY--KCDAQKLAPFIKKYLKSAVVNGKLIQTKGKGASGSFKLS-----ASAKK-EKDPKAKSKVLSAEKKVQSKKVASKKIGVSSKKTAVGAADKKPKAKKAVATKKTAENKKTEKAKAKDAKKTGIIKSKPAATKAKVTAAKPKAVIAKASKAKPAVSAKPKKTVKKASVSATAKKPKAKTTAAKK------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q4AB94-1", "uniprot_id": "Q4AB94_DROME", "id": "Q4AB94-1", "name": "", "aln": "MSDSAVATSASPVAAPPATVEKKVGQKKASGSAG-TKAKKASATPSHPPTQQMGDASIKNLKERGGSSLLAIKKYITATY--KCDAQKLAPFIKKYLKSAVVNGKLIQTKGKGASGSFKLS-----ASAKK-EKDPKAKSKVLSAEKKVQSKKVASKKIGVSSKKTAVGAADKKPKAKKAVATKKTAENKKTEKAKAKDAKKTGIIKSKPAATKAKVTAAKPKAVIAKASKAKPAVSAKPKKTVKKASVSATAKKPKAKTTAAKK------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P43276-1", "uniprot_id": "H15_MOUSE", "id": "P43276-1", "name": "Histone H1.5", "aln": "MSETAPAETAA-----PAPVEKSPAKKKTTKKAG---AAKRKATG--PPVSELITKAVSASKERGGVSLPALKKALAAG---GYDVEKNNSRIKLGLKSLVSKGTLVQTKGTGASGSFKLN-----KKAASGEAKPKAK-KTGAAKAKKPAGATPKKPKKTAGAKKTVKKTPKKAKKPAAAGVKKVAKSPKKAKAAAK-------------PKKAAKSPAKPKAVKSKASKPK---VTKPK--------TAKPKAAKAKKAVSKKK-----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D3ZBN0-1", "uniprot_id": "H15_RAT", "id": "D3ZBN0-1", "name": "Histone H1.5", "aln": "MSETAPAETTA-----PAPVEKSPAKKKT-KKAG---AAKRKATG--PPVSELITKAVSASKERGGVSLPALKKALAAG---GYDVEKNNSRIKLGLKSLVSKGTLVQTKGTGASGSFKLN-----KKVASGEAKPKAK-KTGAAKAKKPTGATPKKPKKTAGAKKTVKKTPKKAKKPAAAGVKKVTKSPKKAKAAAK-------------PKKATKSPARPKAVKSKASKPK---VTKPK--------AAKPKAAKVKKAVSKKK-----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P16401-1", "uniprot_id": "H15_HUMAN", "id": "P16401-1", "name": "Histone H1.5", "aln": "MSETAPAETAT-----PAPVEKSPAKKKATKKAAGAGAAKRKATG--PPVSELITKAVAASKERNGLSLAALKKALAAG---GYDVEKNNSRIKLGLKSLVSKGTLVQTKGTGASGSFKLN-----KKAASGEAKPKAK-KAGAAKAKKPAGATPKKAKKAAGAKKAVKKTPKKAKKPAAAGVKKVAKSPKKAKAAAK-------------PKKATKSPAKPKAVKPKAAKPK---AAKPK--------AAKPKAAKAKKAAAKKK-----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P53551-1", "uniprot_id": "H1_YEAST", "id": "P53551-1", "name": "Histone H1", "aln": "MAPKKSTTKTTSKGKKPATSK---GKEKSTSKAAIKKTTAKKEEASSKSYRELIIEGLTALKERKGSSRPALKKFIKENYPIVGSASNFDLYFNNAIKKGVEAGDFEQPKGPAGAVKLAKKKSPEVKKEKEVSPKPKQAATSVSATASKAKAASTKLAPKKVVKKKSPTVTAKKASSPSSLTYKEMILKSMPQLNDGKGS----------SRIVLKKYVKDTFSSKLKTSSNFDYLFNSAIKKCVENGELVQPKGPSGIIKLNKKKVKLST", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*: . : .:: **. : ::*: .*. : . . :: .: :*: * * *:** : ...: :: :*. * * : *.** ..: .: . . . . .** . :* . .. *.: : **.. : *: . .* . : *::. .. . .* .. ** ", "identical_positions": 29, "similar_positions": 69, "identity": "10.7%" }, { "cls_id": "homologset.agr.MGI:1861586", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I6ABD6-1", "uniprot_id": "A0A8I6ABD6_RAT", "id": "A0A8I6ABD6-1", "name": "", "aln": "MSRQFTCKSGAGNRG-------FSGCSAVLSGGSSSSYRAGGKG---------------LSGGFGSRSLYSLGGPRSITLNMASGSGKNGGFGFGRNRASG-----FAGSIFG-SVALGP-VCPTVCPPGGIHQVTVNESLLAPLNVELDPEIQKVRAQEREQIKALNNKFASFIDKVRFLEQQNQVLETKWELLQQLDLNNCKNNLEPILEGYISNMRKQLETLSGDRVRLDSELRNVRDVVEDYKKKYEEEINRRTAAENEFVLLKKDVDAAYANKVELQAKVDTMDQDIKFFKCLFEAEMAQIQSHISDMSVILSMDNNRNLDLDSIIDEVRAQYEEIALKSKAEAEALYQTKFQELQLAAGRHGDDLKNTKNEITELTRFIQRLRSEIENAKKQASNLETAIADAEQRGDSALKDARAKLDELEGALHQAKEELARMLREYQELMSLKLALDMEIATYRKLLESEECR-MSGEYSSPVSISIISSTSGSGGYGFRP---STVSGGYVANSTSCISGVCSVRGGENRSRGSASDYKDS---LTKGSSLSTPSKKGGRVLGLDSSGLPCGALLIDTRSFSASAQVQPVPSTSRWLCPYRTTWLLGSPSGLLHLLSFCRSSCL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9R0H5-1", "uniprot_id": "K2C71_MOUSE", "id": "Q9R0H5-1", "name": "Keratin, type II cytoskeletal 71", "aln": "MSRQFTCKSGASNRG-------FSGCSAVLSGGSSSSYRAGGKG---------------LSGGFGSRSLYSLGGGRSITLNMASGSGKNGGFGFGRNRASG-----FAGSIFG-SVALGP-VCPAVCPPGGIHQVTVNESLLAPLNVELDPEIQKVRAQEREQIKALNNKFASFIDKVRFLEQQNQVLQTKWELLQQLDLNNCKNNLEPILEGHISNMRKQLETLSGDRVRLDSELRNVRDVVEDYKKKYEEEINRRTAAENEFVLLKKDVDAAYANKVELQAKVDTMDQDIKFFKCLFEAEMAQIQSHISDMSVILSMDNNRNLDLDSIIDEVRAQYEEIALKSKAEAEALYQTKFQELQLAAGRHGDDLKNTKNEITELTRFIQRLRSEIENAKKQASNLETAIADAEQRGDSALKDARAKLDELEGALHQAKEELARMLREYQELMSLKLALDMEIATYRKLLESEECR-MSGEYSSPVSISIISSTSGSGGYGFRP---STVSGGYVANSTSCISGVCSVRGGENRSRGSASDYKDT---LTKGSSLSTPSKKGGR----------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q3SY84-1", "uniprot_id": "K2C71_HUMAN", "id": "Q3SY84-1", "name": "Keratin, type II cytoskeletal 71", "aln": "MSRQFTCKSGAAAKGG------FSGCSAVLSGGSSSSFRAGSKG---------------LSGGFGSRSLYSLGGVR--SLNVASGSGKSGGYGFGRGRASG-----FAGSMFG-SVALGP-VCPTVCPPGGIHQVTVNESLLAPLNVELDPEIQKVRAQEREQIKALNNKFASFIDKVRFLEQQNQVLETKWELLQQLDLNNCKNNLEPILEGYISNLRKQLETLSGDRVRLDSELRNVRDVVEDYKKRYEEEINKRTAAENEFVLLKKDVDAAYANKVELQAKVESMDQEIKFFRCLFEAEITQIQSHISDMSVILSMDNNRNLDLDSIIDEVRTQYEEIALKSKAEAEALYQTKFQELQLAAGRHGDDLKNTKNEISELTRLIQRIRSEIENVKKQASNLETAIADAEQRGDNALKDARAKLDELEGALHQAKEELARMLREYQELMSLKLALDMEIATYRKLLESEECR-MSGEFPSPVSISIISSTSGGSVYGFRP---SMVSGGYVANSSNCISGVCSVRGGEGRSRGSANDYKDT---LGKGSSLSAPSKKTSR----------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6NWF6-1", "uniprot_id": "K2C8_DANRE", "id": "Q6NWF6-1", "name": "Keratin, type II cytoskeletal 8", "aln": "MSTYSKKTSYTVKSSS------SGSIPRNFSSLSYSGPSMSRQS-------------------------YSARSSYG-GVNRGMGAGMGGGSGFISSS-----------SAYGLGMGMGTGMGAGVVAP--IQAVTVNKSLLAPLNLEIDPNIQIVRTQEKEQIKTLNNRFASFIDKVRFLEQQNKMLETKWSLLQNQTAT--RSNIDAMFEAYIANLRRQLDSLGNDKMKLEADLHNMQGLVEDFKNKYEDEINKRTECENEFVLIKKDVDEAYMNKVELEAKLESLTDEINFLRQIFEEEIRELQSQIKDTSVVVEMDNSRNLDMDAIVAEVRAQYEDIANRSRAEAEMWYKSKYEEMQTSANKYGDDLRSTKTEIADLNRMIQRLQSEIDAVKGQRANLENQIAEAEERGEMAVRDAKGRIKDLEDALQRAKQDMARQIREYQDLMNVKLALDIEIATYRKLLEGEEDRLATG--IKAINISKQSTSYGGYPMESAGSSYSTYSSGYSSGLSGGYGGG--YSGGYSGGYSSGSGYSDTVSQTKKSVVIKMIETKDGRVVSESSEVVQD-----------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "F1QV31-1", "uniprot_id": "F1QV31_DANRE", "id": "F1QV31-1", "name": "", "aln": "MSTSFKTFTSSGSMSGGMGGGMGGGIRKNFSSMSTSAVPMGSRSSVSFRRSGGGGGGGGFGAGSGGSFSYSMGGGGG-GGGSGFGGGFGSGGGFGSGGGFGGGAGFGGGSAYGGGAGFGGGFGPGGVVP--ITAVTVNQNLLAPLNLEIDPNIQVVRTQEKEQIKTLNNRFASFIDKVRFLEQQNKVLETKWSLLQEQTTT--RSNIDAMFEAYIANLRRQLDGLGNEKMKLEGELKNMQNLVEDFKNKYEDEINKRAAVENEFVLLKKDVDAAYMNKVELEAKVDSLQDEINFLRAIFEEELRELQSQIKDTSVVVEMDNSRNLDMDAIVAEVRAQYEDIANRSRAEAESWYKQKFEEMQSSAGKYGDDLRNTKAEIADLNRMISRLQNEIEAVKGQRANLEAQIAEAEERGELAVKDAKLRIKDLEDALQRAKQDMARQVREYQELMNVKLALDIEIATYRKLLEGEESRIASGGNTATIHIQESSSSSGGGGGGFGYGGGSGYGGGSGFGGGSGYGGGSGFGGGSGFGYGGGSGMS-----IGGGSGMSMSGGGGGQISMSRSSIVSSQKRRF------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "** . : : . .. :*. * *. . :. ** . . . *.* ..* ** . * :* . .:* . . * * ****:.******:*:**:** **:**:****:***:***************::*:***.***: . :.*::.::*.:*:*:*:**: *..::::*:.:*:*::.:***:*::**:***:*: ******:***** ** *****:**:::: ::*:*:: :** *: ::**:*.* **::.***.****:*:*: ***:***:** :*:**** *: *::*:* :*.::****:.** **::*.*:*.*::.**: .* * :*** **:**:**: *::**: ::.:**.**::**:::** :****:**.:*****:**********.** * :* .: *. *:: *. * ..* . . .* ** . . ..... . . :. .: ", "identical_positions": 213, "similar_positions": 169, "identity": "34.13%" }, { "cls_id": "homologset.agr.MGI:1861600", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I6G891-1", "uniprot_id": "A0A8I6G891_RAT", "id": "A0A8I6G891-1", "name": "", "aln": "MDREGPRGPRRGTSQENEQWKKETLEDEFSGVRLQKLEQQRQLFEKKQRRKRQEPLMVQANPDASLRHRRPRRGEERFQSDSSWGLGVGSPFLQENVPQAHLPSGAHSALVTMSYVGDGSGERAPLLSPRGAVYTRGNGPAVR-HLCWLPDSSDSDVEEVTMEDIPVISRPPKTH--LANRRRGWLASPGPGISE---EEEVEPKDARVEDKTPSPDPDP--TENSDRVHGDSASCNMEENTAKKNIETASGIGDEDPEKKEATESTETNNALVASKVLQGD-GDTSNHSAWNMTCPMPRTPGPRLGEDMEAYVLLPAPREHMVQCRIVRNKHGVDKGMFPSYYLYLEAEDGVAVRSSPLGHFLLAGRKRKRSKTSNYLISLDPKDMSRNGNNFVGKVRSNVLGTKFTIFDNGVNPERNYWIPDSARIREELGVVCYETNVLGFRGPRKMTVILPGMDSRKQRMKVQPQNDQDSILSRVQKGARHGLLLLQNKAPSWSDESGAYVLNFHGRVTRASVKNFQIVHPDEPDHLVLQFGRVAPNIFTMDFRYPLCPLQAFAICLSSFDGKLAFF", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P46686-1", "uniprot_id": "TULP2_MOUSE", "id": "P46686-1", "name": "Tubby-related protein 2", "aln": "MDREGPRGPRSGASQENEQWKKETLEDEFSGVRLQKLEQQRQLFEKKQRRKRQEPLMVQANPDATLRHRRPRRGEERFQSDSSWGLGVGSPFLQENVPQAHLPSGAHSALVTMSYVADGSGERAPLLSPRGAVYTRGNGPAVRHHLCWLPDSSDSDVEEVTMEDIPVISRPPQTN--LANLRRGWLASPGPGISQEEKEEEVGSTDARVEDKTPSPDPDPDPTVNSDGDHGDLAPCKVEENTAQKNTETASGIGDEDREKGEVTESTETNYAPVASKVLQGDDGDASNHNAWNMTCPQPRIPGPRLGEDMEAYVLLPAPRDHMVQCRIVRNKHGMDKGMFPSYYLYLEAEDGVA-------HFLLAGRKRKRSKTSNYLISLDPKDMSRNGSNFVGKVRSNVLGTKFTIFDNGVNPERSYWVPDSARIREELGVVCYETNVLGFRGPRKMTVILPGMDSRKQRMKVQPQNDQDSILSRVQKGAGHGLLLLQNKAPSWSDESGAYVLNFHGRVTRASVKNFQIVHPDEPDHLVLQFGRVAPNIFTMDFRYPLCPLQAFAICLSSFDGKLAFF", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O00295-1", "uniprot_id": "TULP2_HUMAN", "id": "O00295-1", "name": "Tubby-related protein 2", "aln": "------------MSQDNDTLMRDILGHELAAMRLQKLEQQRRLFEKKQRQKRQELLMVQANPDASPWLWRSCLREERLLGDR----GLGNPFLRKKVSEAHLPSGIHSALGTVSCGGDGRGERG-LPTPRTEAVFRNLGLQSP-FLSWLPDNSDAELEEVSVENGSVSPPPFKQS--PRIRRKGWQAHQRPGTRA---EGESDSQDMGDAHKSPNMGPNP--GMDGDCVYENLAFQKEED--LEKKREASESTG---------TNSSAAHNEELS-KALKGEGGTDSDH-MRHEASLAIRSPCPGLEEDMEAYVLRPALPGTMMQCYLTRDKHGVDKGLFPLYYLYLETSDSLQ-------RFLLAGRKRRRSKTSNYLISLDPTHLSRDGDNFVGKVRSNVFSTKFTIFDNGVNPDREHLTRNTARIRQELGAVCYEPNVLGYLGPRKMTVILPGTNSQNQRINVQPLNEQESLLSRYQRGDKQGLLLLHNKTPSWDKENGVYTLNFHGRVTRASVKNFQIVDPKHQEHLVLQFGRVGPDTFTMDFCFPFSPLQAFSICLSSFN------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q1L8C0-1", "uniprot_id": "Q1L8C0_DANRE", "id": "Q1L8C0-1", "name": "", "aln": "-MEDAEVRQQKLDNQRSLLIKKQQRRRADARMVTANPDICSKTRKQKPECDDTVLLISQSQSNTSLNDTQPEHIYENTVEEICLGELSVSSRTEEASEEIAQTVPVIIKKIDLEISPKHSTTSTLDTDGQADEKKTKKKGVKKGQTKLLEPKAALEVEENEKKEKKSVKKKEKTNGTKGRAKTGEQSSVQTDSVVDFSINEEKKPESESEDEGKDWSKSPVPPTPKKKQMKPMRCHLSDSEEENDEKEEKDKKKEAKKTPKKSKKNTKSVNSLASLNSNYKEHSSDSDSSDIGKSSPMS-------LEDLEQFAMRPAPRDVTIQCRITRDRRGVEKGIYPTYYLHMEKEDGKR-------VFLMAGRKRKKCKTSNYLISVDPTDLSRDTDSYIGKLRSNVLGTKFTVFDNGENPERKPFIKEMDTLRQELAAIFYEKNVLGFKGPRKMTVIIPGMHENDERVVIRPKSELESLLTRYENGNKENLVTLVNKSPSWNEQTQSYVLNFHGRVTQASVKNFQIVHPDNVDYIVMQFGRVADDVFSMDYSFPMCALQAFAITLSSFDGKLACE", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .* . :: : : : : : ::* . . *: *::.::: :. *. : .. .: : . :. . : * .: ::** :: : : * : .. * : .: . . .* . :. :.: * . .:.: : : : : . *: :. **:* :.: ** :** :.*:::*::**::* ***::* .*. **:*****::.********:**..:**: ..::**:****:.****:**** **:*. : :*:**..: ** ****: ********:** ....:*: ::* .: :*:*:* :.* ..*: * **:***..:. *.********:*********.*.. :::*:*****. : *:**: :*:..****:* ****: ", "identical_positions": 136, "similar_positions": 157, "identity": "23.82%" }, { "cls_id": "homologset.agr.MGI:1861601", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0ABK0M5H2-1", "uniprot_id": "A0ABK0M5H2_RAT", "id": "A0ABK0M5H2-1", "name": "Cleavage and polyadenylation specificity factor subunit 2", "aln": "MTSIIKLTTLSGVQEESALCYLLQVDEFRFLLDCGWDEHFS--VDIIDSLRKHVHQIDAVLLSHPDPLHLGALPFAVGKLG----LNCAIYATIPVYKMGQMFMYDLYQSR--HNTEDFTLFTLDDVDAAFDKIQQLKFSQIVNLKGKGHGLSITPLPAGHMIGGTIWKIVKDGEEEIVYAVDFNHKRE--------IHLNGCSLEMLSRPSLLITDSFNATYVQPRRKQRDEQLLTNVLETLRGDGNVLIAVDTAGRVLELAQLLDQIWRT--KDAGLGVYSLALLNNVSYNVVEFSKSQVEWMSDKLMRCFEDKRNN-PFQFRHLSLCHGLSDLARVPS------------------------PKVVLASQPDLECGFSRDLFIQWCQ-----------DPKNSIILTYRTTPGTLARFLIDNPSE-KVTEIELRKR--------------------VKLEGKELEEYVEKEKLKKEAAKKLEQSKEADIDSSDESDVEEDVDQPTAHKTK-HDLMMKGEGSRKGSFFKQ--AKKSYPMFPAPEERIKWDEYGEIIKDSLFRPEDFLVPELQATEEEKS----KLESGLTNGEEP------MDQDLSDVPTKCVSATESIEIKARVTYIDYEGRSDGDSIKKIINQMKPRQLIIVHGPPEASQDLAECCRAFGGKDIKVYMPKLHETVDATSETHIYQVRLKDSLVSSLQFCKAKDAELAWIDGVLDMRVSKVDTGVILEEGELKDDGEDS-------EMQVDAPSDSSVIAQQKAMKSLFGDDEKELGEESEVIPTLEPLPPHEVPGHQSVFMNEPRLSDFKQVLLREGIQAEFVGGVLVCNN-QVAVRRTETGRIGLEGCLCQDFYRIRDLLYEQYAIV", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O35218-1", "uniprot_id": "CPSF2_MOUSE", "id": "O35218-1", "name": "Cleavage and polyadenylation specificity factor subunit 2", "aln": "MTSIIKLTTLSGVQEESALCYLLQVDEFRFLLDCGWDEHFS--VDIIDSLRKHVHQIDAVLLSHPDPLHLGALPFAVGKLG----LNCAIYATIPVYKMGQMFMYDLYQSR--HNTEDFTLFTLDDVDAAFDKIQQLKFSQIVNLKGKGHGLSITPLPAGHMIGGTIWKIVKDGEEEIVYAVDFNHKRE--------IHLNGCSLEMLSRPSLLITDSFNATYVQPRRKQRDEQLLTNVLETLRGDGNVLIAVDTAGRVLELAQLLDQIWRT--KDAGLGVYSLALLNNVSYNVVEFSKSQVEWMSDKLMRCFEDKRNN-PFQFRHLSLCHGLSDLARVPS------------------------PKVVLASQPDLECGFSRDLFIQWCQ-----------DPKNSIILTYRTTPGTLARFLIDNPTE-KVTEIELRKR--------------------VKLEGKELEEYVEKEKLKKEAAKKLEQSKEADIDSSDESDVEEDVDQPSAHKTK-HDLMMKGEGSRKGSFFKQ--AKKSYPMFPAPEERIKWDEYGEIIK-----PEDFLVPELQATEEEKS----KLESGLTNGEEP------MDQDLSDVPTKCVSATESIEIKARVTYIDYEGRSDGDSIKKIINQMKPRQLIIVHGPPEASQDLAECCRAFGGKDIKVYMPKLHETVDATSETHIYQVRLKDSLVSSLQFCKAKDAELAWIDGVLDMRVSKVDTGVILEEGELKDDGEDS-------EMQVDAPSDSSAMAQQKAMKSLFGEDEKELGEETEIIPTLEPLPPHEVPGHQSVFMNEPRLSDFKQVLLREGIQAEFVGGVLVCNN-QVAVRRTETGRIGLEGCLCQDFYRIRDLLYEQYAIV", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9P2I0-1", "uniprot_id": "CPSF2_HUMAN", "id": "Q9P2I0-1", "name": "Cleavage and polyadenylation specificity factor subunit 2", "aln": "MTSIIKLTTLSGVQEESALCYLLQVDEFRFLLDCGWDEHFS--MDIIDSLRKHVHQIDAVLLSHPDPLHLGALPYAVGKLG----LNCAIYATIPVYKMGQMFMYDLYQSR--HNTEDFTLFTLDDVDAAFDKIQQLKFSQIVNLKGKGHGLSITPLPAGHMIGGTIWKIVKDGEEEIVYAVDFNHKRE--------IHLNGCSLEMLSRPSLLITDSFNATYVQPRRKQRDEQLLTNVLETLRGDGNVLIAVDTAGRVLELAQLLDQIWRT--KDAGLGVYSLALLNNVSYNVVEFSKSQVEWMSDKLMRCFEDKRNN-PFQFRHLSLCHGLSDLARVPS------------------------PKVVLASQPDLECGFSRDLFIQWCQ-----------DPKNSIILTYRTTPGTLARFLIDNPSE-KITEIELRKR--------------------VKLEGKELEEYLEKEKLKKEAAKKLEQSKEADIDSSDESDIEEDIDQPSAHKTK-HDLMMKGEGSRKGSFFKQ--AKKSYPMFPAPEERIKWDEYGEIIK-----PEDFLVPELQATEEEKS----KLESGLTNGDEP------MDQDLSDVPTKCISTTESIEIKARVTYIDYEGRSDGDSIKKIINQMKPRQLIIVHGPPEASQDLAECCRAFGGKDIKVYMPKLHETVDATSETHIYQVRLKDSLVSSLQFCKAKDAELAWIDGVLDMRVSKVDTGVILEEGELKDDGEDS-------EMQVEAPSDSSVIAQQKAMKSLFGDDEKETGEESEIIPTLEPLPPHEVPGHQSVFMNEPRLSDFKQVLLREGIQAEFVGGVLVCNN-QVAVRRTETGRIGLEGCLCQDFYRIRDLLYEQYAIV", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F1QVV4-1", "uniprot_id": "F1QVV4_DANRE", "id": "F1QVV4-1", "name": "Cleavage and polyadenylation specificity factor subunit 2", "aln": "MTSIIKLTALSGVQEESALCYLLQVDEFRFLLDCGWDETFS--MDIIDSLKRYVHQVDAVLLSHPDHVHLGALPYAVGKLG----LNCTIYATIPVYKMGQMFMYDLYQSR--HNTEDFTLFTLDDVDSAFDKIQQLKYSQIVNLKGKGHGLSITPLPAGHMIGGTIWKIVKDGEEEIIYGVDFNHKRE--------IHLNGCSLESLSRPSLLITDSFNASYVQPRRKQRDEQLLTNVMETLRGDGNVLIAVDTAGRVLELAQLLDQIWRT--KDAGLGVYSLALLNNVSYNVVEFSKSQVEWMSDKLMRCFEDKRNN-PFQFRHLSLCHSLSDLARVPS------------------------PKVVLCSQPDLESGFSRELFIQWCQ-----------DAKNSVILTYRTTPGTLARYLIDNPGE-KRIELEIRKR--------------------CRLEGRELEEYMEKERMKKEAAKKLEQAKEVDLDSSDESDMEDDLEQPAVVKTKHHDLMMKGEGGRKGGFFKQ--AKKSYPMFPTHEERIKWDEYGEIIR-----PEDFLVPELQATEEEKS----KLESGLTNGEEP------MEQDLSDVPTKCTSTTQTLDIRARVMYIDYEGRSDGDSIKKIINQMKPRQLIIVHGPPDASQDLAESCKAYSGKDIKVYIPKLQETVDATSETHIYQVRLKDSLVSSLQFCKARDTELAWIDGVLDMRVEKVDTGVIVELGEAKDEAEEGGEQGMEVTEELNTEPSTAAAANQRAMKTLFGEDEKEISEESDVIPTLEPLPAHEVPGHQSVFINEPRLSDFKQVLLREGIQAEFVGGVLVCNN-LVAVRRTEAGRICLEGCHCDDYYRIRELLYEQYAVV", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9V3D6-1", "uniprot_id": "CPSF2_DROME", "id": "Q9V3D6-1", "name": "Probable cleavage and polyadenylation specificity factor subunit 2", "aln": "MTSIIKLHTISGAMDESPPCYILQIDDVRILLDCGWDEKFD--ANFIKELKRQVHTLDAVLLSHPDAYHLGALPYLVGKLG----LNCPIYATIPVFKMGQMFMYDLYMSH--FNMGDFDLFSLDDVDTAFEKITQLKYNQTVSLKDKGYGISITPLNAGHMIGGTIWKIVKVGEEDIVYATDFNHKKE--------RHLSGCELDRLQRPSLLITDAYNAQYQQARRRARDEKLMTNILQTVRNNGNVLIAVDTAGRVLELAHMLDQLWKN--KESGLMAYSLALLNNVSYNVIEFAKSQIEWMSDKLTKAFEGARNN-PFQFKHIQLCHSLADVYKLPAG-----------------------PKVVLASTPDLESGFTRDLFVQWAS-----------NANNSIILTTRTSPGTLAMELVENCAPGKQIELDVRRR--------------------VDLEGAELEEYLRTQ---GEKLNPLIVKPDVEEESSSES--EDDIEMS--VITGKHDIVVRPEGRHHSGFFKS--NKRHHVMFPYHEEKVKCDEYGEIINLDDYRIADATGYEFVPMEEQNKENVKKEEPGIGAEQQANGGIVDNDVQLLEKPTKLISQRKTIEVNAQVQRIDFEGRSDGESMLKILSQLRPRRVIVIHGTAEGTQVVARHCEQNVG--ARVFTPQKGEIIDVTSEIHIYQVRLTEGLVSQLQFQKGKDAEVAWVDGRLGMRVKAIEA-----------------------PMDVTVEQDASVQEGK--------------------TLTLETLADDEIPIHNSVLINELKLSDFKQTLMRNNINSEFSGGVLWCSNGTLALRRVDAGKVAMEGCLSEEYYKIRELLYEQYAIV", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q12102-1", "uniprot_id": "CFT2_YEAST", "id": "Q12102-1", "name": "Cleavage factor two protein 2", "aln": "---MTYKYNCCDDGSGTTVGSVVRFDNVTLLIDPGWNPSKVSYEQCIKYWEKVIPEIDVIILSQPTIECLGAHSLLYYNFTSHFISRIQVYATLPVINLGRVSTIDSYASAGVIGPYDTNKLDLEDIEISFDHIVPLKYSQLVDLRSRYDGLTLLAYNAGVCPGGSIWCISTYS-EKLVYAKRWNHTRDNILNAASILDATGKPLSTLMRPSAIITTLDRFGSSQPFKK-RSKIFKDTLKKGLSSDGSVIIPVDMSGKFLDLFTQVHELLFESTKINAHTQVPVLILSYARGRTLTYAKSMLEWLSPSLLKTWENRNNTSPFEIGSRIKIIAPNELSKYPGSKICFVSEVGALINEVIIKVGNSEKTTLILTKPSFECASSLDKILEIVEQDERNWKTFPEDGKSFLCDNYISIDTIKEEPLSKEETEAFKVQLKEKKRDRNKKILLVKRESKKLANGNAIIDDTNGERAMRNQDILVENVNGVPPIDHIMGGDEDDDEEEENDNLLNLLKDNSEKSAAKKNTEVPVDIIIQPSAASKHKMFPFNPAKIKKDDYGTVVDFTMFLPDDSDNVNQNSRKRPLK------DGAKTTSPVN-------EEDNKNEEEDGYNMSDPISKRSKHRASRYSGFSGTGEAENFDNLDYLKIDKTLSKRTISTVNVQLKCSVVILNLQSLVDQRSASIIWPSLKSRKIVLSAPKQIQNEEITAKLIKKNIEVVNMPLNKIVEFSTTIKTLDISIDSNLDNLLK------WQRISDSYTVATVVGRLVKESLPQVNNHQKTASRSKLVLKPLHGSSRSHKTGALSIGDVRLAQLKKLLTEKNYIAEFKGEGTLVINEKVAVRKINDAETIIDGTPSELFDTVKKLVTDMLAKI", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : .. . :. :::.*:. :*:* **: : *. .: : :*.::**:* *** . :: . :***:** ::*:: * * * . * : *:*:: :*::* **:.* *.*:.: *::: . ** **:** * . . *.::*. :**.:: . .* *. * *** :** . *. :: *.: : .: : : .:*.*:*.** :*:.*:* :.:: * . .: :*. . ..: ::** :**:* .* : :*. .*. **:: . :: : *. ..:: : *.:*.. : : ::: . : :. : . : * .: ::. ::* ::. : *. :..: * : : . ...:. *:: : .. : : .:: . : *** ::* *:** :: * : . :. . : . : : : . . ..:. .:: :.* *. . :: . : : . .: : * : : . : : : : : . : .. * . :: :: *. *. : : :. : . :: :.: :*:::*: * .:. :** * * :*:*: : .. ::* .: : ::.*: : * :", "identical_positions": 108, "similar_positions": 268, "identity": "12.23%" }, { "cls_id": "homologset.agr.MGI:1861602", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8BQZ5-1", "uniprot_id": "CPSF4_MOUSE", "id": "Q8BQZ5-1", "name": "Cleavage and polyadenylation specificity factor subunit 4", "aln": "MQEIIASVDHIKFDLEIAVEQQLGAQPLPFPGMDKSGAAVCEFFLK----AACGKGGMCPFRHIS--GEKTVVCKHWLRGLCKKGDQCEFLHEYDMTKMPECYFYSKF---------------------------------GPLCRHRHTRRVICVNYLVGFCPEGPS-CKFMHPRFELP----MG----TTEQP------PLPQQTQPPTK--------------------------RAPQVIGV--MQSQNSSAGN-----RGPRPLEQVTCYKCGEKGHYANRCTKGHLAFLSGQ----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O95639-1", "uniprot_id": "CPSF4_HUMAN", "id": "O95639-1", "name": "Cleavage and polyadenylation specificity factor subunit 4", "aln": "MQEIIASVDHIKFDLEIAVEQQLGAQPLPFPGMDKSGAAVCEFFLK----AACGKGGMCPFRHIS--GEKTVVCKHWLRGLCKKGDQCEFLHEYDMTKMPECYFYSKFGECSNK-ECPFLHIDPESKIKDCPWYDRGFCKHGPLCRHRHTRRVICVNYLVGFCPEGPS-CKFMHPRFELP----MG----TTEQP------PLPQQTQPPAKQSNNPPLQRSSSLIQLTSQNSSPNQQRTPQVIGV--MQSQNSSAGN-----RGPRPLEQVTCYKCGEKGHYANRCTKGHLAFLSGQ----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q5FVR7-1", "uniprot_id": "CPSF4_RAT", "id": "Q5FVR7-1", "name": "Cleavage and polyadenylation specificity factor subunit 4", "aln": "MQEIIASVDHIKFDLEIAVEQQLGAQPLPFPGMDKSGAAVCEFFLK----AACGKGGMCPFRHIS--GEKTVVCKHWLRGLCKKGDQCEFLHEYDMTKMPECYFYSKFGECSNK-ECPFLHIDPESKIKDCPWYDRGFCKHGPLCRHRHTRRVICVNYLVGFCPEGPS-CKFMHPRFELP----MG----TTEQP------PLPQQTQPPTK--------------------------RAPQVIGV--MQSQNSSAGN-----RGPRPLEQVTCYKCGEKGHYANRCTKGHLAFLSGQ----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9VPT8-1", "uniprot_id": "CPSF4_DROME", "id": "Q9VPT8-1", "name": "Cleavage and polyadenylation specificity factor subunit 4", "aln": "MDILLANVSGLQFKAERDLIEQVGAIPLPFYGMDKSIAAVCNFITRNG--QECDKGSACPFRHIR--GDRTIVCKHWLRGLCKKGDQCEFLHEYDMTKMPECYFYSRFNACHNK-ECPFLHIDPQSKVKDCPWYKRGFCRHGPHCRHQHLRRVLCMDYLAGFCPEGPS-CKHMHPHFELPPLAELGKDQLHKKLPTCHYCGELGHKANSCKQYVGSLEHRNNINAMDHSGGHSGGYSGHSGHIEGADDMQSNHHSQPHGPGFVKVPTPLEEITCYKCGNKGHYANKCPKGHLAFLSNQHSHK", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q06102-1", "uniprot_id": "YTH1_YEAST", "id": "Q06102-1", "name": "mRNA 3'-end-processing protein YTH1", "aln": "MSLIHPDTAKYPFKFEPFLRQEYSFSLDPDR-------PICEFYNSREGPKSCPRGPLCPKKHVLPIFQNKIVCRHWLRGLCKKNDQCEYLHEYNLRKMPECVFFSKNGYCTQSPDCQYLHIDPASKIPKCENYEMGFCPLGSSCPRRHIKKVFCQRYMTGFCPLGKDECDMEHPQFIIP-----------------------------------------------------------------------DEGSKLR------IKRDDEINTRKMDEEKERRLNAIINGEV----------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*. : ... *. * : :: . * .:*:* * :* ** :*: :..:**:*********.****:****:: ***** *:*: *. * ::* ::*:* *:.**** * . *. **:* :* :. * . * * :* : * :*.: ", "identical_positions": 59, "similar_positions": 47, "identity": "19.54%" }, { "cls_id": "homologset.agr.MGI:1861606", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8BGV3-1", "uniprot_id": "TACD2_MOUSE", "id": "Q8BGV3-1", "name": "Tumor-associated calcium signal transducer 2", "aln": "MARGLDLAP------LLLLLLAMATRFCTAQSNCTCPTNKMTVCDTNGPGGVCQCRAMGSQVLVDCSTLTSKCLLLKARMSARKSGRSLVMPSEHAILDNDGLYDPECDDKGRFKARQCNQTSVCWCVNSVGVRRTDKGDQSLRCDEVVRTHHILIELRHRPTDRAFNHSDLDSELRRLFQERYKLHPSFLSAVHYEEPTIQIELRQNASQKGLRDVDIADAAYYFERDIKGESLFMGRRGLDVQVRGEPLHVERTLIYYLDEKPPQFSMKRLTAGVIAVIAVVSVAVVAGVVVLVVTKRRKSGKYKKVELKELGEMRSEPSL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0ABK0L8S5-1", "uniprot_id": "A0ABK0L8S5_RAT", "id": "A0ABK0L8S5-1", "name": "Tumor-associated calcium signal transducer 2", "aln": "MARGLDLAP------LLLLLLAMVAGFCTAQINCTCPTNKMTVCNSNGPGGVCQCRAIGSQVLVDCSTLTSKCLLLKARMSARKSSRRLVNPSEHAILDNDGLYDPECDDKGRFKARQCNQTSVCWCVNSVGVRRTDKGDQSLRCDEVVRTHHILIELRHRPTDRAFNHSDLDSELRRLFKERYKLHPSFLAAVHYEEPTIQIELQQNASQKGLRDVDIADAAYYFERDIKGESLFVGRRGLDVQVRGEPLHVERTLIYYLDEKPPQFSMKRLTTGLIAVIAVVAVALVAGVVVLVVTNRRKSGKYKKVELKELGEMRSEPSL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P09758-1", "uniprot_id": "TACD2_HUMAN", "id": "P09758-1", "name": "Tumor-associated calcium signal transducer 2", "aln": "MARGPGLAPPPLRLPLLLLVLAAVTGHTAAQDNCTCPTNKMTVCSPDGPGGRCQCRALGSGMAVDCSTLTSKCLLLKARMSAPKNARTLVRPSEHALVDNDGLYDPDCDPEGRFKARQCNQTSVCWCVNSVGVRRTDKGDLSLRCDELVRTHHILIDLRHRPTAGAFNHSDLDAELRRLFRERYRLHPKFVAAVHYEQPTIQIELRQNTSQKAAGDVDIGDAAYYFERDIKGESLFQGRGGLDLRVRGEPLQVERTLIYYLDEIPPKFSMKRLTAGLIAVIVVVVVALVAGMAVLVITNRRKSGKYKKVEIKELGELRKEPSL", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "**** .*** ****:** .: . :** ************..:**** *****:** : ******************* *..* ** *****::********:** :***************************** ******:********:****** ********:******:***:***.*::*****:*******:**:***. ****.**************** ** ***::******:*********** **:*******:*:****.** **:***:.***:*:***********:*****:*.****", "identical_positions": 251, "similar_positions": 45, "identity": "77.71%" }, { "cls_id": "homologset.agr.MGI:1861607", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q6DFZ1-1", "uniprot_id": "GBF1_MOUSE", "id": "Q6DFZ1-1", "name": "Golgi-specific brefeldin A-resistance guanine nucleotide exchange factor 1", "aln": "---------MVDKNIYIIQGEINIVVGAIKRNARWS---------------------------THIPLDEERDPLLHSFSNLKEVLNSVTELSEIEPNVFLRPFLEVIRSEDTTGPITGLALTSVNKFLSYALIDPTHEGTAEGMENMADAVTHARFVGTDPASDEVVLMKILQVLRTLLLTPVGTHLTNESVCEIMQSCFRICFEMRLSELLRKSAEHTLVDMVQLLFTRLPQFKEEPKSYVGTNMKKLKMRAGGMSDSSKWKKQKRSPRPPRHTTKVTPGSELPTPNGATL-------PSNLTGGVP-FIDAPTSISSASSEAASTVVSPCTDSGLELSSQTTSKEDLTDLEQAGSPREITTSEPGSSEMGASDQLDPQ-EGAHVEKAQSASVESIPEVLEECTSPADHSDSASVHDMDYVNPRGVRFTQ-SSQKEGTALVPYGLPCIRELFRFLISLTNPHD-RHNSEVMIHMGLHLLTVALESAP--VAQCQTLLGLIKDEMCRHLFQLLS-VERLNLYAASLRVCFLLFESMREHLKFQLEMYIKKLMEIITVE---------NPKMPYEMKEMALEAVVQLWR-IPSFVTELYINYDCDYYCSNLFEDLTKLLSKNAFPVSGQLYTTHL--LSLDALLTVIDSTESHCQAKVLNTLNQQEKKETARPGFEAVDGNPETNKSERATSDGKSTGVALDARGLHFPSGGWLSTEHGKPGCRDLEEAGDSGADKKFTRKPPRFSCLLPDPRELIEIKNKKKLLITGTEQFNQKPKKGIQFLQEKGLLTIPMDNTEVAQWLRENPRLDKKMIGEFVSDRKNMD--LLESFVSTFSFQGLRLDEALRLYLEAFRLPGEAPVIHRLLEVFTEHWRSCNGSP-------------------------FANSDACFALAYAVIMLNTDQHNHNVRKQNAPMTLEEFRKNLKGVNGGKDFEQDILEDMYHAIKNEEIVMPEEQTG-----------LVRENYVWSVLLHRGASPEGVFLRVPPGSYDLDLFTMTWGPTIAALSYVFDKSLEETIIQKAISGFRKCAMISAHYGLSDVFDNLIISLCKFTALSSESIENLPS----------VFGSNPKAHIAAKTVFHLAHRHGDILREGWKNIMEAMLQLFRAQLLPKAMVEVEDFVDPNGKISLQREETPSNRGESTVLSFVSWLTLSGPEQSSVRGPSTENQEAKRVALDCIKQCDPEKMITESKFLQLESLQELMKALVSVTPDEE-------TYDEEDAAFCLEMLLRIVLENRDRVGCVWQTVRDHLYHLCVQAQ--DFCFLVERAVVGLLRLAIRLLRREEISGQVLLSLRILLLMKPSVLSRVSHQVAYGLHELLKTNAANIHSGDDWATLFTLLECIGSGVKPPDALQATARADAPDAGAQSDSELPSYHQNDVSLDRGYTSDSEVYTDHGRPGKIHRSATDADMVNSGWLVVGKDDIDNSKPGAGLSRPGPSPLVNQYSLTVGLDLGPHDTKSLLKCVESLSFIVRDAAHITPDNFELCVKTLRIFVEASLNGGCKSQDKRSKSHKYDSKGNRFKKKPKEGSMLRRPRGSNQHATRGGHSDEEEDEGVPASYHTVS--LQVSQDLLDLMHTLHTRAASIYSSWAEEQRHLEGGGQKIEADSRTLWAHCWCPLLQGIACLCCDARRQVRMQALTYLQR-ALLVHDLQKLDALEWESCFNKVLFPLLTKLLENISPA---DVGGMEETRMRASTLLSKVFLQHLSPLLSLS-TFAALWLTILDFMDKYMHAGSSDLLSEAIPESLKNMLLVMDTAEIFHSADARGGGPSALWEITWERIDCFLPHLRDELFKQT----------VIQDPMPAEPHSQK-----------------------PLASTHLTSAAGDPR-----------MPGHPP------LPEIPSEMGVCDSEKPESTRAPSSSSPGSPMASSPSKLSPAQ-----EGPPPLTQPPLILQP--------------------------------------------------------LTSPLQVGVPPMTLPIILNPALIEATSPV--------------------------------------------------------PLLATPR--------PTDPIPTSEVN----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "F1M8X9-1", "uniprot_id": "F1M8X9_RAT", "id": "F1M8X9-1", "name": "Golgi-specific brefeldin A-resistance guanine nucleotide exchange factor 1", "aln": "---------MVDKNIYIIQGEINIVVGAIKRNARWS---------------------------THIPLDEERDPLLHSFSHLKEVLNSGTELSEIEPNVFLRPFLEVIRSEDTTGPITGLALTSVNKFLSCALIDPTHEGTAEGMENMADAVTHARFVGTDPASDEVVLMKILQVLRTLLLTPVGTHLTNESVCEIMQSCFRICFEMRLSELLRKSAEHTLVDMVQLLFTRLPQFKEEPKSYVGTNLKKLKMRAGGMSDSSKWKKQKRSPRPPRHTTKVMPGSELPTPNGAAL-------SSNLTGGMP-FIEAPTSISSASSEAASTVVSPCTDSGLELSSQATSKEDLTDLEQAGSPREITTTEPGSTEIGVSDQLDPQQEGAHVEKAQSASVESIPEVLEECTSPTDHSDSASVHDMDYVNPRGVRFTQ-SSQKEGTALVPYGLPCIRELFRFLISLTNPHD-RHNSEVMIHMGLHLLTVALESAP--VAQCQTLLGLIKDEMCRHLFQLLS-VERLNLYAASLRVCFLLFESMREHLKFQLEMYIKKLMEIITVE---------NPKMPYEMKEMALEAIVQLWR-IPSFVTELYINYDCDYYCSNLFEDLTKLLSKNAFPVSGQLYTTHL--LSLDALLTVIDSTEAHCQAKVLNTLNQQEKKETARPGFEAVDGSPDTYKSERAASDGKATGVPSDAPGLHFSSGGWLSTEHGKPGCSDLEEAGDSGVDKKTTRKPPRFSCLLPDPRELIEIKNKKKLLITGTEQFNQKPKKGIQFLQEKGLLTIPMDNTEVAQWLRENPRLDKKMIGEFVSDRKNMD--LLESFVSTFSFQGLRLDEALRLYLEAFRLPGEAPVIHRLLEVFTEHWRSCNGSP-------------------------FANSDACFALAYAVIMLNTDQHNHNVRKQNAPMTLEEFRKNLKGVNGGKDFEQDILEDMYHAIKNEEIVMPEEQTG-----------LVRENYVWSVLLHRGATPEGIFLRVPPGSYDLDLFTMTWGPTIAALSYVFDKSLEETIIQKAISGFRKCAMISAHYGLSDVFDNLIISLCKFTALSSESIENLPS----------VFGSNPKAHIAAKTVFHLAHRHGDILREGWKNIMEAMLQLFRAQLLPKAMVEVEDFVDPNGKISLQREETPSNRGESTVLSFVSWLTLSGPEQSSVRGPSTENQEAKRVALDCIKQCDPEKMITESKFLQLESLQELMKALVSVTPDEE-------TYDEEDAAFCLEMLLRIVLENRDRVGCVWQTVRDHLYHLCVQAQ--DFCFLVERAVVGLLRLAIRLLRREEISGQVLLSLRILLLMKPSVLSRVSHQVAYGLHELLKTNAANIHSGDDWATLFTLLECIGSGVKPPDALQATARADAPDAGAQSDSELPSYHQNDVSLDRGYTSDSEVYTDHGRPGKMHRSATDADMANSGWLVVGKDDIDNSKPAAGLSRPGPSPLVNQYSLTVGLDLGPHDTKSLLKCVESLSFIVRDAAHITPDNFELCVKTLRIFVEASLNGGCKSQDKRGKSHKYDSKGNRFKKKPKEGSMLRRPRASSQHATRAGHSDEEEDEGVPASYHTVS--LQVSQDLLDLMHTLHTRAASIYSSWAEEQRHLETGGRKIEADSRTLWAHCWCPLLQGIACLCCDARRQVRMQALTYLQR-ALLVHDLQKLDALEWESCFNKVLFPLLTKLLENISPA---DVGGMEETRMRASTLLSKVFLQHLSPLLSLS-TFAALWLTILDFMDKYMHAGSSDLLSEAVPESLKNMLLVMDTAEIFHSADARGGSPSALWEITWERIDCFLPHLRDELFKQT----------VIQDPMPTEPHSQK-----------------------PLASTHLTPAAGDPR-----------MPGHPP------PPEIPSEVGACDPEKPESTRAASSSSPGSPVASSPSKQSPAP-----EGPPPLAQPPLILQP--------------------------------------------------------LTSPLQVGVPPMTLPIILNPALIEATSPV--------------------------------------------------------PLLATPR--------PTDPIPTSEVN----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q92538-4", "uniprot_id": "GBF1_HUMAN", "id": "Q92538-4", "name": "Golgi-specific brefeldin A-resistance guanine nucleotide exchange factor 1", "aln": "---------MVDKNIYIIQGEINIVVGAIKRNARWS---------------------------THTPLDEERDPLLHSFGHLKEVLNSITELSEIEPNVFLRPFLEVIRSEDTTGPITGLALTSVNKFLSYALIDPTHEGTAEGMENMADAVTHARFVGTDPASDEVVLMKILQVLRTLLLTPVGAHLTNESVCEIMQSCFRICFEMRLSELLRKSAEHTLVDMVQLLFTRLPQFKEEPKNYVGTNMKKLKMRAGGMSDSSKWKKQKRSPRPPRHMTKVTPGSELPTPNGTTL-------SSNLTGGMP-FIDVPTPISSASSEAASAVVSPSTDSGLEFSSQTTSKEDLTDLEQPGSPGYSTATEPGSSELGVPEQPDLQQEGTHVEKSQSASVESIPEVLEECTSPADHSDSASVHDMDYVNPRGVRFTQ-SSQKEGTALVPYGLPCIRELFRFLISLTNPHD-RHNSEVMIHMGLHLLTVALESAP--VAQCQTLLGLIKDEMCRHLFQLLS-IERLNLYAASLRVCFLLFESMREHLKFQMEMYIKKLMEIITVE---------NPKMPYEMKEMALEAIVQLWR-IPSFVTELYINYDCDYYCSNLFEELTKLLSKNAFPVSGQLYTTHL--LSLDALLTVIDSTEAHCQAKVLNSLTQQEKKETARPSCEIVDGTREASNTERTASDGKAVGMASDIPGLHLPGGGRLPPEHGKSGCSDLEEAVDSGADKKFARKPPRFSCLLPDPRELIEIKNKKKLLITGTEQFNQKPKKGIQFLQEKGLLTIPMDNTEVAQWLRENPRLDKKMIGEFVSDRKNID--LLESFVSTFSFQGLRLDEALRLYLEAFRLPGEAPVIQRLLEAFTERWMNCNGSP-------------------------FANSDACFSLAYAVIMLNTDQHNHNVRKQNAPMTLEEFRKNLKGVNGGKDFEQDILEDMYHAIKNEEIVMPEEQTG-----------LVRENYVWNVLLHRGATPEGIFLRVPTASYDLDLFTMTWGPTIAALSYVFDKSLEETIIQKAISGFRKCAMISAHYGLSDVFDNLIISLCKFTALSSESIENLPS----------VFGSNPKAHIAAKTVFHLAHRHGDILREGWKNIMEAMLQLFRAQLLPKAMIEVEDFVDPNGKISLQREETPSNRGESTVLSFVSWLTLSGPEQSSVRGPSTENQEAKRVALECIKQCDPEKMITESKFLQLESLQELMKALVSVTPDEE-------TYDEEDAAFCLEMLLRIVLENRDRVGCVWQTVRDHLYHLCVQAQ--DFCFLVERAVVGLLRLAIRLLRREEISAQVLLSLRILLLMKPSVLSRVSHQVAYGLHELLKTNAANIHSGDDWATLFTLLECIGSGVKPPAALQATARADAPDAGAQSDSELPSYHQNDVSLDRGYTSDSEVYTDHGRPGKIHRSATDADVVNSGWLVVGKDDVDNSKPGP--SRPGPSPLINQYSLTVGLDLGPHDTKSLLKCVESLSFIVRDAAHITPDNFELCVKTLRIFVEASLNGGCKSQEKRGKSHKYDSKGNRFKKKSKEGSMLRRPRTSSQHASRGGQSDDDEDEGVPASYHTVS--LQVSQDLLDLMHTLHTRAASIYSSWAEEQRHLETGGQKIEADSRTLWAHCWCPLLQGIACLCCDARRQVRMQALTYLQR-ALLVHDLQKLDALEWESCFNKVLFPLLTKLLENISPA---DVGGMEETRMRASTLLSKVFLQHLSPLLSLS-TFAALWLTILDFMDKYMHAGSSDLLSEAIPESLKNMLLVMDTAEIFHSADARGGGPSALWEITWERIDCFLPHLRDELFKQT----------VIQDPMPMEPQGQK-----------------------PLASAHLTSAAGDTR-----------TPGHPP------PPEIPSELGACDFEKPESPRAASSSSPGSPVASSPSRLSPTP-----DGPPPLAQPPLILQP--------------------------------------------------------LASPLQVGVPPMTLPIILNPALIEATSPV--------------------------------------------------------PLLATPR--------PTDPIPTSEVN----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A1Z8W8-1", "uniprot_id": "A1Z8W8_DROME", "id": "A1Z8W8-1", "name": "Golgi-specific brefeldin A-resistance guanine nucleotide exchange factor 1", "aln": "-------MALPGNGIYVVRGEMATLMTAMRRGTRWN---------------------------ATAYVDDENDSLLKLFIDLKHELNRIEDLRQIEPQVFLAPFLEVIRTADATGPLTSLALASVNKLLSYGLIDPTSPNLADIVERIADAVTHARFMGTDQSSDGVTFMRVIEVLHTLIRSPEGAAVSNVSMCEVMLSCFKISFEPRLSELLRRSAEKSLKDMVLLFFMRLPQFAEER----SDTMLQKRFTIGDAASGATQEKLKRKTVAQAQTAPRKS-SAVEEPPQTPQ-------SANLT--VPGHLKAPILATTPASPAG----------------------NILDMQGKITQTPTTTASTGEDETTVPETPVIQVESTESEPLLDGETGEATSTLAEANS------------SEYINSVGVRFTQQSTDHDVTSLSPYGLPFIQELFRFLIILCNPLD-KQNSDSMMHTGLSLLTVAFEVAADNIGKYEGLLELVKDDLCRNLISLLS-SERLSIFAADLQLCFLLFESLRGHLKFQLEAYLRKLSEIIASD---------NPKTPYEMRELALDNLLQLWR-IPGFVTELYINYDCDLYCTDMFESLTNLLSKYTLSATNAVYSTHI--ISMDTLLSVIDSIERNCAASKNSSNNRESLPEAAP----ATGGSRHSRHN-------------SGLEGIVIDSGNSVAAEEKVENIASFINASSHRLRLQSGGEG-----VGITSEQLAKVKQKKRLLSQGTERFNQRPEKGIQYLQEHGILNAELDPMQVALFLRENPGLDKKMIGEYISKKKNVDSKILINFVDSFDFTGLRVDQALRLYLETFRLPGEAPLIFLVLEHFSDHWHKQNQDP-------------------------FANVDAAFRLAYAIIMLNMDQHNSNAKRLNVPMTLEDFTKNLRGLNGGEDFDQEMLAQVFNAIKNEEIVMPAEQTG-----------LVRENYQWKVLLRRGDTHDGHFHYVHDASYDVEIFNIVWGASLSALSFMFDKS-TETGYQRTLAGFSKSAAISAHYNLHSDFDALVLTLCKFTTLLSSVEQHEPAPANNETQQAVNFGLNGKAQAAMRTVFLLVHDYGDCLRESWKHILDLYLQLFRLKLLPKSLIEVEDFCEANGKAMLILEKPREKQESGLFSSLYSFISSEGQ-----REPTYEEQDFIKLGRKCIKECQLDQMLQESKFVQLESLQELLKCVLALLKAPQGHKSIGLPYAEDQTVFWMEFLVKIVVHNRDRMIPLWPAVRDQMYLLLMGSASCGYDYLLNRCIVAVLKLAIYLMRNEELCPIVLQSLKMLLMLKPALLLRISKQISIGIYELLKTSAQNIHSEQDWQIIFNLLECVGAGAVPP-NYDDAQLPLPPNGSAKSDGAISGEEDATAVPERGYTSDSEITKASAAPAVSSPSAEN-------WILVNNKDSELTTASRPQSPPSLSAPP-VNTLVYNCQLLDHAPFALFKCWDSLAFIVRSVAHITPYNFEACVRCIRIFVEACRDGGIRQRRKLESAAKQKSSKKRSERKP---GMASSASSSNLTLLTGDPSDNQINGNAAEQEDLAQRYEQLSIQLLDLMYTLYTRTAQIFRWWAEEGCTVP--------QSAALWSPGWCPLLQGIARLAMDRRREVRTHAISCLQQRALLVHDLQTLSGTEWCSCFHQVLFPLLNELLPESNAAGQLDAALLEESRIRTATIMSKVFLQHLTTLIELGNAFNELWLDILDYIERFMKVG-SDTLSEQMQEILKNMLLVMHSVRVFHNQD--GSLQQALWELTWRRIGEFLPNLKEELFHDEGKRAQTLTNPAPQAAVAAAPQQQLPAVTILPRQTQVSNELVVSAPTPPAATPLLGSPVESPRRSIILQPPMADVLQQPPSFVFAQPIIVPPQPPAVTDPIPPSTLLPDLVNEATAAAVQATTTSPTHSPQEAEQPASIVQQTNIVTTNNTYNSYAIEVPMAPETTAEQFGQQQQQLLYQQYYQQYQAQQQQLPAPASDPAINVPISHLLAGNAYPSLPKMPQASIVHSFAPVYESQAATSGAGTAAADIYQEYVQNPYNLTLQQHPQQQLHQQQQQQQQQATGMANAFPAVATPANYFNVNVDPSSIPPGSELLYGQQ", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P39993-1", "uniprot_id": "GEA2_YEAST", "id": "P39993-1", "name": "ARF guanine-nucleotide exchange factor 2", "aln": "MSDR---EFVTVDPVTIIIKECINLSTAMRKYSKFTSQSGVAALLGGGSEIFSNQDDYLAHTFNNLNTNKHNDPFLSGFIQLRLMLNKLKNLDNIDSLTILQPFLLIVSTSSISGYITSLALDSLQKFFTLNIINESSQNYIGAHRATVNALTHCRFEGSQQLSDDSVLLKVVFLLRSIVDSPYGDLLSNSIIYDVLQTILSLACNNRRSEVLRNAAQSTMIAVTVKIFSKLKTIEPVN-------VNQIYINDESYTNDVLKADTIGTNVESKEEGSQEDPIGMKVNNEEAISEDDGIEEE--------------------------------------------------------------HIHSEKSTNGAEQLDIVQKTTRSNSRIQAYADDN----------------------------------------------YGLPVVRQYLNLLLSLIAPENELKHSYSTRIFGLELIQTALEISGDRLQLYPRLFTLISDPIFKSILFIIQNTTKLSLLQATLQLFTTLVVILGNNLQLQIELTLTRIFSILLDDGTANNSSSENKNKPSIIKELLIEQISILWTRSPSFFTSTFINFDCNLDRADVSINFLKALTKLALPESALTTTESVPPICLEGLVSLVDDMFDHMKDIDREEFGRQKNE------------------------------------------------------------------------------------MEILKKRDRKTEFIECTNAFNEKPKKGIPMLIEKGFIASDSDKDIAEFLFNNNNRMNKKTIGLLLCHPDKVS--LLNEYIRLFDFSGLRVDEAIRILLTKFRLPGESQQIERIIEAFSSAYCENQDYDPSKISDN----------AEDDISTVQPDADSVFILSYSIIMLNTDLHNPQVKEH---MSFEDYSGNLKGCCNHKDFPFWYLDRIYCSIRDKEIVMPEEHHGNEKWFEDAWNNLISSTTVITEIKKDTQSVMDKLTPLELLNFDRAIFKQVGPSIVSTLFNIYVVASDDHISTRMITSLDKCSYISAFFDFKDLFNDILNSIAKGTTLINSSHD---------------------DELSTLAFEYGPMPLVQIKFEDTNTEIPVSTDAVRFGRSFKGQLNTVVFFR-----IIRRNKDPKIFSKELWLNIVNIILTLYEDLILSP--DIFPDLQKRLKLSNLPKPSPEISINKS-----KESKGLLSTFASYLKGDE-------EPTEEEIKSSKKAMECIKSSN-------------------IAASVFGNESNITADLIKTLLDSAKTEKNADNSRYFEAELLFIIELTIALFLFCKEEKELGKFILQKVFQLSHTKGLTKRTVRRMLTYK------------------------------------------------------------------------ILLISLCADQTEYLSKLINDELLKKGDIFTQKFFATNQGKEFLKRLFSLTESEFYRGFLLGNEN----------FWKFLRKVTAMKEQSESIFEYLNESIKTDSNILTNENFMWVLGLLDEISSMGAVGNHWEIEYKKLTESGHKIDK--ENPYKKSIELSLKSIQLTSHLLE------------------DNNDLRKNEIFAIIQALAHQCINPCKQISEFAVVTLEQTLINKIEIPTNEMESVEELIEGGLLPLLN-------------SSETQEDQKILISSILTIISNVYLHYLKLGKTSNETFLKILSIFNKFVEDS-------DIEKKLQQLILDKKSIEKGNGSSSHGSAHEQTPESNDVEIEATAPIDDNTDDDNK--------------PKLSDVEKD-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P47102-1", "uniprot_id": "GEA1_YEAST", "id": "P47102-1", "name": "ARF guanine-nucleotide exchange factor 1", "aln": "MHDVPMETVLAVNPATMIVKECINLCSAMNKQSRDKSQTSVAALLGGGSDIFLSQSDSFVDSFHNLPTSSYHDPLISGLVQLRLKINDLKGLDSLNALELLKPFLEIVSASSVSGYTTSLALDSLQKVFTLKIINKTFNDIQIAVRETVVALTHCRFEASKQISDDSVLLKVVTLLRDIITSSFGDYLSDTIIYDVLQTTLSLACNTQRSEVLRKTAEVTIAGITVKLFTKLKLLDPPT-------KTEKYINDESYTDNNLKDDIIGTTTSDNDLSSTDD--------DSAVADDN------------------------------------------------------------------------KNEKPVQQVIREQENDEETAEKAENVEPN----------------------------------------------YGITVIKDYLGLLLSLVMPENRMKHTTSAMKLSLQLINAAIEISGDKFPLYPRLFSLISDPIFKSVLFIIQSSTQYSLLQATLQLFTSLVVILGDYLPMQIELTLRRIFEILEDTTISGDVS---KQKPPAIRELIIEQLSILWIHSPAFFLQLFVNFDCNLDRSDLSIDFIKELTKFSLPAAAVNTSNNIPPICLEGVLSLIENIYNDLQRFDRAEFVKNQKE------------------------------------------------------------------------------------IDILKQRDRKTEFILCVETFNEKAKKGIQMLIEKGFIDSDSNRDIASFLFLNNGRLNKKTIGLLLCDPKKTS--LLKEFIDLFDFKGLRVDEAIRILLTKFRLPGESQQIERIVEAFSSKYSADQSNDKVELEDKKAGKNGSESMTEDDIIHVQPDADSVFVLSYSIIMLNTDSHNPQVKDH---MTFDDYSNNLRGCYNGKDFPRWYLHKIYTSIKVKEIVMPEEHHGNERWFEDAWNNLISSTSVMTEMQRDFTNPISKLAQIDILQYEKAIFSNVRDIILKTLFKIFTVASSDQISLRILDAISKCTFINYYFSFDQSYNDTVLHLGEMTTLAQSS-------------------------AKAVELDVDSIPLVEIFVEDTGSKISVSNQSIRLGQNFKAQLCTVLYFQ-----IIKEISDPSIVSTRLWNQIVQLILKLFENLLMEPNLPFFTNFHSLLKLPELPLPDPDISIRKA-----KMSRSLLSTFASYLKGDE-------EPSEEDIDFSIKAFECVKASH-------------------PLSSVFENNQLVSPKMIETLLSSLVIEKTSENSPYFEQELLFLLEISIILISEASYGQEFGALIADHMINISNLDGLSKEAIARLASYK------------------------------------------------------------------------MFLVSRFDNPRDILSDLIEHDFLVKNEIFNTKYYESEWGKQVINDLFTHLNDVKYNERALKNVK----------FWNFLRILISAKDRQFAVYTFLEKYIQNGDIFVDDGNFMNILSLLDEMSCAGAVGTKWEQNYENSVEDGCEAPE--SNPYRSIIDLSSRSINITADLLSTVGR--------------SNSALNKNEIIAAIQGLAHQCLNPCDELGMQALQALENILLSRASQLRTEKVAVDNLLETGLLPIFE-------------LDEIQDVKMKRITSILSVLSKIFLGQLVEGVTSNETFLRVLNVFNKYVDDP-------TVERQLQELIISKREIEKE------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . :: * : *:.: :: . .. .*.:: : .*: :* * .::. :* *** :: : . :* *.*** *::*.:: :*: : . . . *:**.** .:. ** .::::: :*: :: :. * ::: : ::: : : :. : : **:**.:*: :: :. :* :* : : : . :.. . . . . . : : . . **:. ::: : :*: * * : ::: .* *: .*:* : . *: *:.* : : :: ::. : .: * *:: *. : * :*:* : :: .*: : * ::*: :: : ** *.*. . ::*:**: ::: .: : *:* ::. : : : :.:: ::::::. . ::. :: : :::* : .: **::.:*** * *:*:: : . : :* ::** ** :.. .: . :* .:: *.* ***:*:*:*: * ******: * ::* *:. : : .: *: * *:*::**** * ** :.: *::::: **:* . :** * :: :*: :***** *: * *: .. . : : . . : : .:: :*. . : :* :: : : : : .: *.: *. .:.: . :: : : : *:* .. . : *. : : .* *. : . : : . . .: . : : : : . : : :: : : *:. . : : *:: : : : : : : :: * : : : . . .* ::: :. :: . * : . . : : :::. . . : . *:. :. : : . : *:. :. : .. . . : . . : : . . . . : . ::* :: : .. * . :*.:* . : :: *: *:. : . . . :. *:*:: :: : : : .:: : : . : :* :*. :::::. : . *::::: . ", "identical_positions": 151, "similar_positions": 445, "identity": "6.97%" }, { "cls_id": "homologset.agr.MGI:1861622", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9JLJ3-1", "uniprot_id": "AL9A1_RAT", "id": "Q9JLJ3-1", "name": "4-trimethylaminobutyraldehyde dehydrogenase", "aln": "-----------------------MSTGTFVVSQPLNYRGGARVEPVDASG-TEKAFEPATGREIATFKCSGEKEVNLAVENAKAAFKIWSKKSGLERCQVLLEAARIIKERRDEIAIMETINNGKSIFEARLDVDTSWQCLEYYAGLAASMAGEHIQLPGGSFGYTRREPLGVCLGIGAWNYPFQIACWKSAPALACGNAMIFKPSPFTPVSALLLAEIYTKAGAPNGLFNVVQGGAATGQFLCQHRDVAKVSFTGSVPTGMKIMEMAAKGIKPITLELGGKSPLIIFSDCNMKNAVKGALLANFLTQGQVCCNGTRVFVQKEIADAFTKEVVRQTQRIKIGDPLLEDTRMGPLINAPHLERVLGFVRSAKEQGATVLCGGEPYAPEDPKLKHGYYMTPCILTNCTDDMTCVKEEIFGPVMSILTFETEAEVLERANDTTFGLAAGVFTRDIQRAHRVAAELQAGTCYINNYNVSPVELPFGGYKKSGFGRENGRVTIEYYSQLKTVCVEMGDVESAF", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9JLJ2-1", "uniprot_id": "AL9A1_MOUSE", "id": "Q9JLJ2-1", "name": "4-trimethylaminobutyraldehyde dehydrogenase", "aln": "-----------------------MSTGTFVVSQPLNYRGGARVEPVDASG-TEKAFEPATGRVIATFACSGEKEVNLAVENAKAAFKLWSKKSGLERCQVLLEAARIIKERKDEIATVETINNGKSIFEARLDVDTCWQCLEYYAGLAASMAGEHIQLPGGSFGYTRREPLGVCVGIGAWNYPFQIACWKSAPALACGNAMIFKPSPFTPVSALLLAEIYTKAGAPPGLFNVVQGGAATGQFLCHHREVAKISFTGSVPTGVKIMEMSAKGVKPITLELGGKSPLIIFSDCNMENAVKGALMANFLTQGQVCCNGTRVFVQKEIADKFINEVVKQTQKIKLGDPLLEDTRMGPLINAPHLERVLGFVKLAKEQGATVLCGGEVYVPEDPKLKHGYYMTPCILTNCRDDMTCVKEEIFGPVMSILTFGTEAEVLERANDTTFGLAAGVFTRDIQRAHRVAAELQAGTCYINNYNVSPVELPFGGYKKSGFGRENGRVTIEYYSQLKTVCVEMGDVESAF", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P49189-1", "uniprot_id": "AL9A1_HUMAN", "id": "P49189-1", "name": "4-trimethylaminobutyraldehyde dehydrogenase", "aln": "-----------------------MSTGTFVVSQPLNYRGGARVEPADASG-TEKAFEPATGRVIATFTCSGEKEVNLAVQNAKAAFKIWSQKSGMERCRILLEAARIIREREDEIATMECINNGKSIFEARLDIDISWQCLEYYAGLAASMAGEHIQLPGGSFGYTRREPLGVCVGIGAWNYPFQIASWKSAPALACGNAMVFKPSPFTPVSALLLAEIYSEAGVPPGLFNVVQGGAATGQFLCQHPDVAKVSFTGSVPTGMKIMEMSAKGIKPVTLELGGKSPLIIFSDCDMNNAVKGALMANFLTQGQVCCNGTRVFVQKEILDKFTEEVVKQTQRIKIGDPLLEDTRMGPLINRPHLERVLGFVKVAKEQGAKVLCGGDIYVPEDPKLKDGYYMRPCVLTNCRDDMTCVKEEIFGPVMSILSFDTEAEVLERANDTTFGLAAGVFTRDIQRAHRVVAELQAGTCFINNYNVSPVELPFGGYKKSGFGRENGRVTIEYYSQLKTVCVEMGDVESAF", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q7ZVB2-1", "uniprot_id": "A9A1A_DANRE", "id": "Q7ZVB2-1", "name": "4-trimethylaminobutyraldehyde dehydrogenase A", "aln": "MAQQPLLSLPEFQ---------SVSTGTLVVKEPLNFWGGARVKPRDTKN-SEPVYEPATGRVLCDMIPCGEEEVDQAIKSAHSAYLKWSQLSGMERSRIMLEAARIIRERRNAIAKAEVANNGKSITEAEVDIDVAWQCIEYYAGIAPTLSGQHIQLPGGSFAYTRREPLGVCVGIGAWNYPFQIAAWKSAPALACGNAMVFKPSPMTPVTAVMLAEIYKEAGVPDGLFNVVQGGAETGSLLCHHPMVAKVSFTGSVPTGKKVMEMAAKSVKQVTLELGGKSPLIIFKDCELENAIKGALMANFLTQGEVCCNGTRVFVQREIMPKFLEEVVKRTKAISVGDPLCEGTRMGALISKPHMEKVLGFIKQAKEQGGKVLCGGERFVPNDPKLKDGYFVSPCVLDNCRDDMTCVKEEIFGPVMSVLPFDTEEEVLQRANNTTFGLASGVFTRDIARAHRVAANLQAGTCYINNYNVGPVEVPFGGYKMSGFGRENGTVTIEYYSQLKTVVVEMGDVESLF", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "B0S7W5-1", "uniprot_id": "B0S7W5_DANRE", "id": "B0S7W5-1", "name": "", "aln": "MAQQPLLSLPEFQ---------SVSTGTLVVKEPLNFWAGARVKPSNTKN-SEPVYEPATGRVLCDMIPCGEEEVDQAIKSAHSAYLKWSQLSGMERSRIMLEAARIIRERRDAIAKTDVANNGTSITEAKVDIDLAWKCIEYYAGIAPTLSGQHIQLPGGSFAYTRREPLGVCVGIGAWNYPFQIAAWKSAPAIACGNAMVFKPSPMTPVTAVMLAEIYKEAGVPDGLFNVVQGGPETGSLLCHHPMVAKVSLTGGVPTGKKVLEMAAKGVKQVTLELGGKSPLIIFNDCELENAIKGALMANFLTKGEVCCNGTRVFVQREIMPKFLEEVVKRTKAISVGDPLCEGTRMGALISKPHMEKVLGFIKQAKEQGAKVLCGGEQFVPNDPKLKDGYFVSPCVLDNCRDDMTCVKEEIFGPVMSVLPFDTEEEVLQRANNTTFGLASGVFTRDIARAHRVIANLQAGMCYINNYNVCPVEVPFGGYKMSGFGKENGALTIEYYSQLKTVVVEMGDVESLF", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q802W2-1", "uniprot_id": "A9A1B_DANRE", "id": "Q802W2-1", "name": "4-trimethylaminobutyraldehyde dehydrogenase B", "aln": "MALMRCLLPPGFYRTLYHPWTRCASSGTLQIKDPLNFWCGARVDLKDVKTKSEPVFEPATGRVLCRLQTCGSAEVDAAVRNASAAFKVWRKLSGMERARVMLEAARLIEKRREEIAEMEVINNGKSITEARLDVDSARLSIEYFAGQATTLSGQHVQLPGGSFAYTRREPFGVCVGIGAWNYPFQIAAWKSAPAIACGNSMVFKPSPLTPVTAVLLAEIYRQAGAPEGLFNVVQGGQETGSLLCLHPSVEKVSFTGSVPTGKKIMEMASRGVKAVTLELGGKSPLIIFEDTDLENAVRGALMANFLSQGQVCSNGTRVFVQSSIVPQFLKEVVRRTKAISIGDPLLDETRMGALVSKAHLDKVLRYVEQAKNEGAQVLCGGEPFSPADPKLKDGYYMTPCVLDSCTDDMTCVKEEIFGPVMSVLTFDTEDEVLRRANDSDLGLAAGVFTKDVKRAHRVIENLQAGSCFINNYNITPVEVPFGGFKASGIGRENGQVTIEFYSQLKTVVVEMGDVDSLF", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *:**: :.:***: ****. :.. :* .:****** :. : .*. **: *:..* :*: * : **:**.:::*****:*.:*.: ** : ***.** **.:*:* . .:**:** *.:::*:*:*******.******:***:************.******:****:*:*****:***:*::***** :**.* ********* **.:** * * *:*:**.**** *::**:::.:* :*************.* :::**::***:****::*:**.******** .* * :***::*: *.:**** : ****.*:. .*:::** ::. **::*. *****: : * *****.**:: **:* .* ****************:*.* ** ***.***:: :***:****:*: ***** :**** *:*****: ***:****:* **:*:*** :***:******* ******:* *", "identical_positions": 290, "similar_positions": 134, "identity": "55.98%" }, { "cls_id": "homologset.agr.MGI:1861630", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q63618-1", "uniprot_id": "ESPN_RAT", "id": "Q63618-1", "name": "Espin", "aln": "MALEQAMQAARRGDLDVLRSLHAAGLLGPSLRDPLDALPVHHAARSGKLHCLRYLVEEVALPAVSRARNGATPAHDAAATGYLSCLQWLLTQGGCRVQEKDNSGATVLHLAARFGHPDVVNWLLYQGGANSAITTDTGALPIHYAAAKGDLPSMKLLVGHYPEGVNAQTNNGATPLYLACQEGHLEVTKYLVQECSADPHLRAQDGMTPLHAAAQMGHNPVLVWLVSFADVSF-EQDHDGATAMHFAASRGHTKVLSWLLLHGAEISQDLWGGTPLHDAAENGELECCQILAVNGAGLDVRDHDGYTAADLADFNGHTHCSRYLRTVQTLSLEHRVLSRDPSMDLEAKQPDSGMSSPNTTMS--VQPP-NFDLGSPTSTLSNYDSCSSSHSSSKGQR-------STR---GARSSDLQSYMDMLNPE---PRSKQGKPSSLPPPPP--PSFPPPPPP--GTQLPPPPPGYPAPNPPVGLHLDNIYMQTKNKLRHVEVDSLKK----------EPSSGDGYSGLRRQDSGLLRQDSELL-----LRHNTGLRRQDSDRKQRSFSKQPSTGDYYRQLGRSPGEPLAARPGMAHSEEA------------------------------ALLPGNHVHNGCSADSK-ASRELPPPPPPPP--LPEALSSPPPAPPLPIEG--------AGAACGQRRSSSSTG------------------------STKSFNMMSPTGDNSELLAEIKAGKSLKPTPQSKGLTTVFSGSGQPASQPESP----------------QPAVSPGPSRARSPTPPASGPQP----------LLNGSIVPAPPATLAPGVHLDVEALIPTLDEQGRPIPEWKRQVMVRKLQQKMQEEEEQRRKEEEEEARLASLPAWRRDILRKKLEEEREQKRKEEERQKLEEIQRAKEQSEKLRTLGYDEAKLAPWQRQVILKKGEIPK-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9ET47-1", "uniprot_id": "ESPN_MOUSE", "id": "Q9ET47-1", "name": "Espin", "aln": "MALEQALQAARRGDLDVLRSLHAAGLLGPSLRDSLDALPVHHAARSGKLHCLRYLVEEVALPAVSRARNGATPAHDAAATGYLSCLQWLLTQGGCRVQEKDNSGATVLHLAARFGHPDVVKWLLYQGGANSAITTDTGALPIHYAAAKGDLPSLKLLVGHYPEGVNAQTNNGATPLYLACQEGHLEVTKYLVQECSADPHLRAQDGMTPLHAAAQMGHNPVLVWLVSFADVSFSEQDHDGATAMHFAASRGHTKVLSWLLLHGAEISQDLWGGTPLHDAAENGELECCQILAVNGAGLDVRDHDGYTAADLAEFNGHTHCSRYLRTVQTLSLEHRVLSRDQSMDLEAKQLDSGMSSPNTTMS--VQPM-TFDLGSPTSTFSNYDSCSSSHSSSKGQR-------SNRGIPGARAADLQSYMDMLNPEKSLPRGKLGKPSPPPPPPPPPPSFPPPPPPT-GTQPPPPPPGYPAPNPPVGLHLNNIYMQTKNKLRHVEVDSLKEPKVELNDQFAQPSSGDGHSGLHRQDSGLLRQDSELLHRQELLRHSTGLRRQDSDRKQRSFSKQPSTGDYYRQLGRSPGEPLAARPGMAHSEEA------------------------------ALLPGNHVHNGCSADSK-ASRELPPPPPPPP--LPEALSSPPPAPPLPIEG--------AGAACGQRRSSSSTGK---------------VRVLRHRKSTKSFNMMSPTGDNSELLAEIKAGKSLKPTPQSKGLTTVFSGSGQPASQPESP----------------QPLVSPAPSRTRSPTPPASGSQP----------LLNGSVVPAPPATPAPGVHLDVEALIPTLDEQGRPIPEWKRQVMVRKLQQKMQEEEEQRRKEEEEEARLASLPAWRRDILRKKLEEEREQKRKEEERQKLEEIQRAKEQSEKLRTLGYDEAKLAPWQRQVILKKGEIPK-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "B1AK53-1", "uniprot_id": "ESPN_HUMAN", "id": "B1AK53-1", "name": "Espin", "aln": "MALEQALQAARQGELDVLRSLHAAGLLGPSLRDPLDALPVHHAARAGKLHCLRFLVEEAALPAAARARNGATPAHDASATGHLACLQWLLSQGGCRVQDKDNSGATVLHLAARFGHPEVVNWLLHHGGGDPTAATDMGALPIHYAAAKGDFPSLRLLVEHYPEGVNAQTKNGATPLYLACQEGHLEVTQYLVQECGADPHARAHDGMTPLHAAAQMGHSPVIVWLVSCTDVSLSEQDKDGATAMHFAASRGHTKVLSWLLLHGGEISADLWGGTPLHDAAENGELECCQILVVNGAELDVRDRDGYTAADLSDFNGHSHCTRYLRTVENLSVEHRVLSRDPSAELEAKQPDSGMSSPNTTVS--VQPL-NFDLSSPTSTLSNYDSCSSSHSSIKGQH-------PPCGLSSARAADIQSYMDMLNPELGLPRGTIGKPT--PPPPP--PSFPPPPPPP-GTQLPPPPPGYPAPKPPVGPQAADIYMQTKNKLRHVETEALKK----------ELSSCDGHD---------------------------GLRRQDSSRKPRAFSKQPSTGDYYRQLGRCPGETLAARPGMAHSEEVRARQPARAGCPRLGPAARGSLEGPSAPPQAALLPGNHVPNGCAADPK-ASRELPPPPPPPPPPLPEAASSPPPAPPLPLES--------AGPGCGQRRSSSSTG------------------------STKSFNMMSPTGDNSELLAEIKAGKSLKPTPQSKGLTTVFSGIGQPAFQPDSP----------------LPSVSPALSPVRSPTPPAAGFQP----------LLNGSLVPVPPTTPAPGVQLDVEALIPTHDEQGRPIPEWKRQVMVRKMQLKMQEEEEQRRKEEEEEARLASMPAWRRDLLRKKLEEEREQKRKEEERQKQEELRREKEQSEKLRTLGYDESKLAPWQRQVILKKGDIAKY", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AC58G7W5-1", "uniprot_id": "A0AC58G7W5_DANRE", "id": "A0AC58G7W5-1", "name": "", "aln": "MVVERTLLAARQGDVQTLKVQFAEKVLNGDVKDVLGATPVHHAARAGKLTCLRYLVDEAGLPANSLARNGASPAHDAAATGNLTCLQWLVTHGGCRAADKDSSGATVLHLASRFSHHEIIDWLLKSEEGDPTVATDTGALPVHYAAAKGDLPSLRLLLEHSPQVVNFQTKNGATPLYLACQEGHLEVVQYLVKDCGAEPSIRANDGMTPLHAAAQMGHNTVIVWLMSFTEISLSDRDNDGATAMHFAASRGHAKVLSWLLLHGGEIMTDSWGGTPLHDAAENGELECCQILVVNGVDLGIRDQDGFSAADLAEYNGHQQCAKYLRTVENMSVEHRVLSRDASADLEYKQPDSGLSSPNATLPNPAPPAGHFDICSPSSSLSNYDSANSSQSSTGEKRSGSPPSRVPTGGTDSAITDMQTYMDMLNPDEACGSHNAKEAAHLPPPPT----FPPPPPPSNPSHIPPPPPAYPAPNPPEEEEVSAEYLKVKRNLRRVDNDVVKK---------EQLNPGENHER---------------------------LRRVDSNRKSRSFSKQPSTGDYYKTLGSDTTDQQPSR-AMAPNEEG-----------------------------SALLEEAADTAPAPENGTGTTEDLPLPPPPPPPPASTFIPAPPPPPPLPSELPPPPPPSTTTPAAAQRRMSSSSNKGHLSSTHLSPSVAPAPETLRQRKSNKSFNMMSPTGDNSELLAEIKAGKSLKPTPHSKGYTTVFSNSGTPGNNGESPSSPPEPLPKPNDTQSAKPESPPPACPPTPPNPTASRSSPQNLSTSQSSDQLTAAVNGNTSVVQNKTSVVDVESLVPTHDEQGRAIPEWKRQVMVRKLQVKMQEEEENKRKAEEEAARLASLPAWRRDIMKKKLEEEKEQKRKDEEQRRMEKESEEKSELERLRTLGYDETKLAPWQKQIILKKGDIAKQ", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*.:*::: ***:*:::.*: .* :*. .::* *.* *******:*** ***:**:*..*** : *****:*****:*** *:*****:::****. :**.*********:**.* :::.*** .:.: :** ****:********:**::**: * *: ** **:*****************.:***::*.*:* **:**************..*:***:* :::*: ::*:**************:**********.** * *********************.***. *.:**:**::****:::*** :*::*****:.:*:******** * :** ** ***:****:*:. . * **: **:*::*****..**:** :: .: :*:*:*******: . :.: ****. ******* :: *****.****:** . *::.*.:**:*: : :*: : .. :.:. *** **.** *:***********: ** . : .:* .** .** *** .. : . ::.:** ****** . .:***.**** * : ....*** ***:. *.*****************************:*** *****. * *. : :** * .* . .*.*.*: .* *..:: .... :***:*:** *****.************:* *******::** *** *****:******:::******:*****:**::: *: . *.: *:********:******:*:*****:*.* ", "identical_positions": 469, "similar_positions": 211, "identity": "48.6%" }, { "cls_id": "homologset.agr.MGI:1861676", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O88426-1", "uniprot_id": "NDK6_RAT", "id": "O88426-1", "name": "Nucleoside diphosphate kinase 6, mitochondrial", "aln": "MTSILRSPQTLQLTLALIKPDAVAHPLILEAVHQQILSNKFLIVRMRELLWKPEDCRRFYREHEGRFFYQRLVEFMTSGPIRAYILAHKDAIQLWRTLMGPTRVFRARHIAPDSIRGSLGLTDTRNTTHGSDSVVSASREIAAFFPDFSEQRWYEEEEPQLRCGPVHYSPEEGIHCAAETGGPKPA---", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O88425-1", "uniprot_id": "NDK6_MOUSE", "id": "O88425-1", "name": "Nucleoside diphosphate kinase 6, mitochondrial", "aln": "MTSILRSPQALQLTLALIKPDAVAHPLILEAVHQQILSNKFLIVRTRELQWKLEDCRRFYREHEGRFFYQRLVEFMTSGPIRAYILAHKDAIQLWRTLMGPTRVFRARYIAPDSIRGSLGLTDTRNTTHGSDSVVSASREIAAFFPDFSEQRWYEEEEPQLRCGPVHYSPEEGIHCAAETGGHKQPNKT", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O75414-1", "uniprot_id": "NDK6_HUMAN", "id": "O75414-1", "name": "Nucleoside diphosphate kinase 6, mitochondrial", "aln": "MASILRSPQALQLTLALIKPDAVAHPLILEAVHQQILSNKFLIVRMRELLWRKEDCQRFYREHEGRFFYQRLVEFMASGPIRAYILAHKDAIQLWRTLMGPTRVFRARHVAPDSIRGSFGLTDTRNTTHGSDSVVSASREIAAFFPDFSEQRWYEEEEPQLRCGPVCYSPEGGVHYVAGTGGLGPA---", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6DI51-1", "uniprot_id": "NDK6_DANRE", "id": "Q6DI51-1", "name": "Nucleoside diphosphate kinase 6, mitochondrial", "aln": "----MRCVKALQLTLAVIKPDAMAHPLILEALHQKILEN-FIIIRKKDLIWRKADSEMFYAEHSGRFFFQRLVEFMSSGPMRAYILAREDAITHWRTMMGPTKVFRARFSSPETLRGKYGLTDTRNTTHGSDSIESAKREISFFFPEFSAEEWMMREEPHFRLGHTEYNEESQIHTVKHT---------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VY27-1", "uniprot_id": "Q9VY27_DROME", "id": "Q9VY27-1", "name": "Nucleoside diphosphate kinase", "aln": "----------MEITLALIKPHVLRNTYAMQQIRALISQN-FTILDQKEVCITKELSERFYAEHKGKFFYHRLTSFMNSGPSYALILQSETCIQKWRSLLGPTKVFRAVYSDPNCIRALYGISDTRNACHGSDSEASALREISILFPEFDAA-----------VGSRQAKREEA----------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :::***:***..: :. :: :: * .* * *: ::: .. ** **.*:**::**..** *** * ** : .* **:::***:**** . *: :*. *::****: ***** ** ***: :**:*. * . * ", "identical_positions": 59, "similar_positions": 44, "identity": "31.22%" }, { "cls_id": "homologset.agr.MGI:1861691", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8K4Y5-1", "uniprot_id": "LGI1_RAT", "id": "Q8K4Y5-1", "name": "Leucine-rich glioma-inactivated protein 1", "aln": "MESESIRRMGNACIPLKRIAYFLCLFSVVLLTEGKKPAKPKCPAVCTCSKDNALCENARSIPRTVPPDVISLSFVRSGFTEISEGSFLFTPSLQLLLFTSNSFDVISDDAFIGLPHLEYLFIENNNIKSISRHTFRGLKSLIHLSLANNNLQTLPKDIFKGLDSLTNVDLRGNSFNCDCKLKWLVEWLGHTNATVEDIYCEGPPEYKKRKINSLSPKDFDCIITEFAKSQDLPYQSLSIDTFSYLNDEYVVIAQPFTGKCIFLEWDHVEKTFRNYDNITGTSTVVCKPIVIDTQLYVIVAQLFGGSHIYKRDGFANKFIKIQDIEVLKIRKPNDIETFKIEDNWYFVVADSSKAGFTTIYKWNGNGFYSHQSLHAWYRDTDVEYLEIARPPLTLRTPHLILSSSSQRPVIYQWSKATQLFINQTDIPNMEDVYAVKHFSVKGDVYICLTRFIGDSKVMKWGGSSFQDIQRMPSRGSMVFQPLQINNYQYAILGSDYSFTQVYNWDAEKAKFVKFQELNVQAPRSFTHVSINKRNFLFASSFKGNTQIYKHVIVDLSA", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9JIA1-1", "uniprot_id": "LGI1_MOUSE", "id": "Q9JIA1-1", "name": "Leucine-rich glioma-inactivated protein 1", "aln": "MESESSRRMGNACIPLKRIAYFLCLFSVVLLTEGKKPAKPKCPAVCTCSKDNALCENARSIPRTVPPDVISLSFVRSGFTEISEGSFLFTPSLQLLLFTSNSFDVISDDAFIGLPHLEYLFIENNNIKSISRHTFRGLKSLIHLSLANNNLQTLPKDIFKGLDSLTNVDLRGNAFNCDCKLKWLVEWLGHTNATVEDIYCEGPPEYKKRKINSLSPKDFDCIITEFAKSQDLPYQSLSIDTFSYLNDEYVVIAQPFTGKCIFLEWDHVEKTFRNYDNITGTSTVVCKPIVIDTQLYVIVAQLFGGSHIYKRDGFANKFIKIQDIEVLKIRKPNDIETFKIEDNWYFVVADSSKAGFTTIYKWNGNGFYSHQSLHAWYRDTDVEYLEIARPPLALRTPHLILSSSSQRPVIYQWSKATQLFTNQTDIPNMEDVYAVKHFSVKGDVYICLTRFIGDSKVMKWGGSSFQDIQRMPSRGSMVFQPLQINNYQYAILGSDYSFTQVYNWDAEKAKFVKFQELNVQAPRSFTHVSINKRNFLFASSFKGNTQIYKHVIVDLSA", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O95970-1", "uniprot_id": "LGI1_HUMAN", "id": "O95970-1", "name": "Leucine-rich glioma-inactivated protein 1", "aln": "MESERSKRMGNACIPLKRIAYFLCLLSALLLTEGKKPAKPKCPAVCTCTKDNALCENARSIPRTVPPDVISLSFVRSGFTEISEGSFLFTPSLQLLLFTSNSFDVISDDAFIGLPHLEYLFIENNNIKSISRHTFRGLKSLIHLSLANNNLQTLPKDIFKGLDSLTNVDLRGNSFNCDCKLKWLVEWLGHTNATVEDIYCEGPPEYKKRKINSLSSKDFDCIITEFAKSQDLPYQSLSIDTFSYLNDEYVVIAQPFTGKCIFLEWDHVEKTFRNYDNITGTSTVVCKPIVIETQLYVIVAQLFGGSHIYKRDSFANKFIKIQDIEILKIRKPNDIETFKIENNWYFVVADSSKAGFTTIYKWNGNGFYSHQSLHAWYRDTDVEYLEIVRTPQTLRTPHLILSSSSQRPVIYQWNKATQLFTNQTDIPNMEDVYAVKHFSVKGDVYICLTRFIGDSKVMKWGGSSFQDIQRMPSRGSMVFQPLQINNYQYAILGSDYSFTQVYNWDAEKAKFVKFQELNVQAPRSFTHVSINKRNFLFASSFKGNTQIYKHVIVDLSA", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "**** :******************:*.:*******************:****************************************************************************************************************************:*****************************************.***************************************************************************:********************.************:***************:*********************************************.*.* :********************.****** ****************************************************************************************************************************************", "identical_positions": 538, "similar_positions": 15, "identity": "96.59%" }, { "cls_id": "homologset.agr.MGI:1861694", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9WUL8-1", "uniprot_id": "CITE4_MOUSE", "id": "Q9WUL8-1", "name": "Cbp/p300-interacting transactivator 4", "aln": "MADHLMLAEGYCLLQVPP---HTHGPHAPRTLQPYAGPGMDSGLRPRGAPLGPPPP--PGTLAYGSFGSPVSFQPFPVSQSPGAGSTHLQSAATPSPGRIPAPPAAAGGPSPLQPAPGAAASLPPPPPP---PALGCMDTELIDEEALTSLELELGLHRVRELPELFLGQSEFDCFSDLGSAPAAGSVSC", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q99MA0-1", "uniprot_id": "CITE4_RAT", "id": "Q99MA0-1", "name": "Cbp/p300-interacting transactivator 4", "aln": "MADHLMLAEGYCLLQVP---------HAPRTLQPYPGPGLDSGLRPRGAPLGPPPP--SGTLAYGSFGSPVSFQPFPVSQPPGAGNAHLQSAATPSPGRMPAPPSAAGGPSPLQPAPGAASPLPLPPPPPLPPALGCMDAELIDEEALTSLELELGLHRVRELPELFLGQSEFDCFSDLGSVPAAGSVSC", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q96RK1-1", "uniprot_id": "CITE4_HUMAN", "id": "Q96RK1-1", "name": "Cbp/p300-interacting transactivator 4", "aln": "MADHLMLAEGYRLVQRPPSAAAAHGPHALRTLPPYAGPGLDSGLRPRGAPLGPPPPRQPGALAYGAFGPPSSFQPFPAVPPPAAGIAHLQPVATPYPGRAAAPPNAPGGPPGPQPAPSAAA----PPPP--AHALGGMDAELIDEEALTSLELELGLHRVRELPELFLGQSEFDCFSDLGSAPPAGSVSC", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*********** *:* * ** *** **.***:**************** .*:****:**.* ******. .*.** :***..*** *** .*** *.***. ****.**: **** *** **:*****************************************.*.******", "identical_positions": 136, "similar_positions": 21, "identity": "71.58%" }, { "cls_id": "homologset.agr.MGI:1861712", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q5XIB1-1", "uniprot_id": "TSSC4_RAT", "id": "Q5XIB1-1", "name": "U5 small nuclear ribonucleoprotein TSSC4", "aln": "MAETEAG-----LEVEEPTEDDTLPSDTVSLSDSDSDLSLPS-GVEVQALSPERLSGESQEDSGPDDPPSHPTGIPTTAVQPFHLRGMSSTFSQRSHSIFDCLESAARQEPCSAPQTSVVDNCSFKRPVAPPSQTPARSLSRVHGNTDPTRVHP--VPDYVSHPERWTKYSLEDVSETSEQSNRDAALAFLSSRS------QASPTDYVPFFNQDPSSCGEGRVVFTKPVRGSEARAERKRVLKKGVVSGAG---------GEASVELAHLAG---PEAEEWSGHQG-QPEVVVPSEAARPESSSGPIGMKTVGFHGSKKRSRDHFRNRDSNPEGPGSERGPSV", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9JHE7-1", "uniprot_id": "TSSC4_MOUSE", "id": "Q9JHE7-1", "name": "U5 small nuclear ribonucleoprotein TSSC4", "aln": "MAETEAG-----LEADEPTEDDTLPSDTVSLSDSDSDLSLPS-GVEVQVLSPERLSEEGQEDSGPEDPPSPPTGTLTTAVQPFHLRGMSSTFSQRSHSIFDCLESAARQAPCSAPQTSVSDNGSFRRPVTPPSQTPARGLSRVHGNTGPTRVLP--VPDYVSHPERWTKYSLEDVSEASEQSNRDAALAFLSSRS------QVSHTDYVPSFNQDPSSCGEGRVVFTKPVRDSEARAERKRVLKKGVGSGAG---------GEAAVELAHLAG---PEAEEWSGHQG-QPEVVVPSEAAHPESSSGPIGVKAVGFHGSKKRSRDHFRNRDGNPGGPGSERGPSV", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9Y5U2-1", "uniprot_id": "TSSC4_HUMAN", "id": "Q9Y5U2-1", "name": "U5 small nuclear ribonucleoprotein TSSC4", "aln": "MAEAGTGEPSPSVEGEHGTEYDTLPSDTVSLSDSDSDLSLPG-GAEVEALSPMGLPGE--EDSGPDEPPSPPSGLLPATVQPFHLRGMSSTFSQRSRDIFDCLEGAARRAPSSVAHTSMSDNGGFKRPLAPSGRSPVEGLGRAHRSPASPRVPP--VPDYVAHPERWTKYSLEDVTEVSEQSNQATALAFLGSQS------LAAPTDCVSSFNQDPSSCGEGRVIFTKPVRGVEARHERKRVLGKVGEPGRGGLGNPATDRGEGPVELAHLAGPGSPEAEEWGSHHGGLQEVEALSGSVHSGSVPGLPPVETVGFHGSRKRSRDHFRNKSSSPEDPGAEV----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q0P4A6-1", "uniprot_id": "TSSC4_DANRE", "id": "Q0P4A6-1", "name": "U5 small nuclear ribonucleoprotein TSSC4", "aln": "MSDRKRK--GNDAPNSLSNRDTVELPDDLSLSDSDSDEPLESFGRKIEDLSS---------SSEEEGETRQQVQSVLQENPSFRLTGGSSSFCDRSRDIFAQLDSAAKLTSKDLGEDNILDG-TLARPAPPSPPHAVQNKCGVGQELTKKQPPGKKLPDYLAHPERWTHYSLEDIDETSDKKNSQVAHEYIRELQDSKRSQKAALETFTPAFNQDHGSSNENKIVFAKPKSKDQSGSRADHAKKEE-------------------VGLQHLDDRVEADEGEALQQSSSWPNKEKKRKWGVTKEEDDTVAPSAV-FTSSKRVNRKNFRKTPDDNDGDKE------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VT74-1", "uniprot_id": "Q9VT74_DROME", "id": "Q9VT74-1", "name": "U5 small nuclear ribonucleoprotein TSSC4", "aln": "------------------MQEFSAKRDALFACLDDASKELRG------------------TALDQSKAKAFSINALDRGNKSGNESGQVMNYRQ-GRSIVTGLDAEDGRLRRMRGKE-----SIFKKPELPIGRCLKPRK----------------TPDYQVNPHKWKKYSLSDVDIS-EQSNSAAALSFLRQMD--------AQREAEGVDNESPPT--DGKIEFKRTSKLSRKLKSLKQQ----------------------EVDDVELDK------PQLRGSKLVMPEYVIGQKPHKPKK----CKTKSEQSRAAGKLQLSHLAEEDEQDD----------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . * : . .*:. * . . . . * .: : .:.*. *:. . : :* * *** :*.:*.:***.*: ::.* .* :: . . : *:. : :.:: * :. . .: * .* : : . . .: .: : . .:: : . ", "identical_positions": 23, "similar_positions": 66, "identity": "6.69%" }, { "cls_id": "homologset.agr.MGI:1861718", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I6AG64-1", "uniprot_id": "A0A8I6AG64_RAT", "id": "A0A8I6AG64-1", "name": "", "aln": "MPGVRKVTMPMAQSSCPGSPPDTGDGWEPVLCKGEVNFGGSGKKRSKFVKVPSNVAPSMLFELLLTEWHLPAPNLVVSLVGEERLFAMKSWLRDVLRKGLVKAAQSTGAWILTSALHVGLARHVGQAVRDHSLASTSTKVRVVAIGMASLDRILHRQLLDGVQ--EDTPIHYPADEGSTQGPLCPLDSNLSHFILVEPGTLGSGNDGLAELQLSLEKHISQQRTGYGGTSSIQIPVLCLLVNGDPSTLERMSRAVEQAAPWLILAGSGGIADVLAALVGQPHLLVPQVTEKQFREKFPSECFSWEAIVHWTELLQNIAAHPHLLTVYDFEQEGSEDLDTVILKALVKACKSHSRDAQDYLDELKLAVAWDRVDIAKSEIFNGDVEWKSCDLEEVMTDALVSNKPDFVRLFVDSGADMAEFLTYGRLQQLYHSVSPKSLLFELLERKHEEGRLTLAG--LGAQQTRELPVGLPAFSLHEVSRVLKDFLHDACRGFYQDGR----RMEERGPPKRPAGQKWLPDLSRKSEDPWRDLFLWAVLQNRYEMATYFWAMGREGVAAALAACKIIKEMSHLEKEAEVARTMREAKYEQLALDLFSECYSNSEDRAFALLVRRNHSWSRTTCLHLATEADAKAFFAHDGVQAFLTKIWWGDMATGTPILRLLGAFTCPALIYTNLISFS-EDAPQRMDLEDLQEPDSLDMEKSFLCSHGGQLEKLTEAPRAPGDL-GPQAAFLLTRWRKFWGAPVTVFLGNVVMYFAFLFLFSYVLLVDFRPPP-QGPSGSEVTLYFWVFTLVLEEIRQGFFTNEDTRLVKKFTLYVEDNWNKCDMVAIFLFIVGVTCRMVPSVFEAGRTVLAIDFMVFTLRLIHIFAIHKQLGPKIIIVERMMKDVFFFLFFLSVWLVAYGVTTQALLHPHDGRLEWIFRRVLYRPYLQIFGQIPLDEIDEARV---NCS--LHPLLLDSSASCPNLYANWLVILLLVTFLLVTNVLLMNLLIAMFSYTFQVVQGNADMFWKFQRYHLIVEYHGRPALAPPFILLSHLSLVLKQVFRKEAQHKQQHLERDLPDPVDQKIITWETVQKENFLSTMEKRRRDSEEEVLRKTAHRVDLIAKYIGGLREQEKRIKCLESQANYCMLLLSSMTDTLAPGGTYSSSQN-CGRRSQPASARDR------EYLEAGLPHSDT---------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9JJH7-1", "uniprot_id": "TRPM5_MOUSE", "id": "Q9JJH7-1", "name": "Transient receptor potential cation channel subfamily M member 5", "aln": "--------MQTTQSSCPGSPPDTEDGWEPILCRGEINFGGSGKKRGKFVKVPSSVAPSVLFELLLTEWHLPAPNLVVSLVGEERPLAMKSWLRDVLRKGLVKAAQSTGAWILTSALHVGLARHVGQAVRDHSLASTSTKIRVVAIGMASLDRILHRQLLDGVHQKEDTPIHYPADEGNIQGPLCPLDSNLSHFILVESGALGSGNDGLTELQLSLEKHISQQRTGYGGTSCIQIPVLCLLVNGDPNTLERISRAVEQAAPWLILAGSGGIADVLAALVSQPHLLVPQVAEKQFREKFPSECFSWEAIVHWTELLQNIAAHPHLLTVYDFEQEGSEDLDTVILKALVKACKSHSQEAQDYLDELKLAVAWDRVDIAKSEIFNGDVEWKSCDLEEVMTDALVSNKPDFVRLFVDSGADMAEFLTYGRLQQLYHSVSPKSLLFELLQRKHEEGRLTLAG--LGAQQARELPIGLPAFSLHEVSRVLKDFLHDACRGFYQDGR----RMEERGPPKRPAGQKWLPDLSRKSEDPWRDLFLWAVLQNRYEMATYFWAMGREGVAAALAACKIIKEMSHLEKEAEVARTMREAKYEQLALDLFSECYGNSEDRAFALLVRRNHSWSRTTCLHLATEADAKAFFAHDGVQAFLTKIWWGDMATGTPILRLLGAFTCPALIYTNLISFS-EDAPQRMDLEDLQEPDSLDMEKSFLCSRGGQLEKLTEAPRAPGDL-GPQAAFLLTRWRKFWGAPVTVFLGNVVMYFAFLFLFTYVLLVDFRPPP-QGPSGSEVTLYFWVFTLVLEEIRQGFFTDEDTHLVKKFTLYVEDNWNKCDMVAIFLFIVGVTCRMVPSVFEAGRTVLAIDFMVFTLRLIHIFAIHKQLGPKIIIVERMMKDVFFFLFFLSVWLVAYGVTTQALLHPHDGRLEWIFRRVLYRPYLQIFGQIPLDEIDEARV---NCS--LHPLLLESSASCPNLYANWLVILLLVTFLLVTNVLLMNLLIAMFSYTFQVVQGNADMFWKFQRYHLIVEYHGRPALAPPFILLSHLSLVLKQVFRKEAQHKRQHLERDLPDPLDQKIITWETVQKENFLSTMEKRRRDSEGEVLRKTAHRVDLIAKYIGGLREQEKRIKCLESQANYCMLLLSSMTDTLAPGGTYSSSQN-CGCRSQPASARDR------EYLESGLPPSDT---------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9NZQ8-1", "uniprot_id": "TRPM5_HUMAN", "id": "Q9NZQ8-1", "name": "Transient receptor potential cation channel subfamily M member 5", "aln": "--------MQDVQGPRPGSPGDAEDRRELGLHRGEVNFGGSGKKRGKFVRVPSGVAPSVLFDLLLAEWHLPAPNLVVSLVGEEQPFAMKSWLRDVLRKGLVKAAQSTGAWILTSALRVGLARHVGQAVRDHSLASTSTKVRVVAVGMASLGRVLHRRILEEAQ--EDFPVHYPEDDGGSQGPLCSLDSNLSHFILVEPGPPGKG-DGLTELRLRLEKHISEQRAGYGGTGSIEIPVLCLLVNGDPNTLERISRAVEQAAPWLILVGSGGIADVLAALVNQPHLLVPKVAEKQFKEKFPSKHFSWEDIVRWTKLLQNITSHQHLLTVYDFEQEGSEELDTVILKALVKACKSHSQEPQDYLDELKLAVAWDRVDIAKSEIFNGDVEWKSCDLEEVMVDALVSNKPEFVRLFVDNGADVADFLTYGRLQELYRSVSRKSLLFDLLQRKQEEARLTLAG--LGTQQAREPPAGPPAFSLHEVSRVLKDFLQDACRGFYQDGRPGDRRRAEKGPAKRPTGQKWLLDLNQKSENPWRDLFLWAVLQNRHEMATYFWAMGQEGVAAALAACKILKEMSHLETEAEAARATREAKYERLALDLFSECYSNSEARAFALLVRRNRCWSKTTCLHLATEADAKAFFAHDGVQAFLTRIWWGDMAAGTPILRLLGAFLCPALVYTNLITFS-EEAPLRTGLEDLQDLDSLDTEKSPLYGLQSRVEELVEAPRAQGDR-GPRAVFLLTRWRKFWGAPVTVFLGNVVMYFAFLFLFTYVLLVDFRPPP-QGPSGPEVTLYFWVFTLVLEEIRQGFFTDEDTHLVKKFTLYVGDNWNKCDMVAIFLFIVGVTCRMLPSAFEAGRTVLAMDFMVFTLRLIHIFAIHKQLGPKIIVVERMMKDVFFFLFFLSVWLVAYGVTTQALLHPHDGRLEWIFRRVLYRPYLQIFGQIPLDEIDEARV---NCS--THPLLLEDSPSCPSLYANWLVILLLVTFLLVTNVLLMNLLIAMFSYTFQVVQGNADMFWKFQRYNLIVEYHERPALAPPFILLSHLSLTLRRVFKKEAEHKREHLERDLPDPLDQKVVTWETVQKENFLSKMEKRRRDSEGEVLRKTAHRVDFIAKYLGGLREQEKRIKCLESQINYCSVLVSSVADVLAQGGGPRSSQH-CGEGSQLVAADHRGGLDGWEQPGAGQPPSDT---------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "S5UH55-1", "uniprot_id": "TRPM5_DANRE", "id": "S5UH55-1", "name": "Transient receptor potential cation channel subfamily M member 5", "aln": "----------MVEKSSERFDKQMAGR------LGDIDFTGVSRTRGKFVRVTSSTDPAEIYQILTKQWGLAPPHLVVALMGGDEVAQLKPWLRDTLRKGLVKAAQSTGAWILTSGLRFGITKNLGQAVRDHSLASTSPKVRVVAIGIAPWNMIQNRDLLLSAK--PDHPATYPTEDLP-YGAVYSLDCNHSHFILVDEDPKRPG--ATGEMRVKMLKHISLQRTGYGGTGSIEIPVLCLLVHGEPRILQKMYKNIQNSIPWLILAGSGGVADILVTLMDR-GCWDADIVQELLINTFP-DGLHSTEITSWTKLIQRILDHGHLLTVHDPEQDS--ELDTVILKALVKACKSQSQEAQDFLDELKLAVAWNRVDIAKSEIFSGDVQWSAQDLEEVMMEALVNDKPDFVRLFVDNGVNIKQFLTYGRLQELYCSVSEKNLLHTLLLKKNQERQAQLARKRMSGNPNNELGDRKFRFTFHEVSKVLKDFLDDTCKGFYQKLP-----AERMGKGRLFHSQKNLPDMDRRCEHPWRDLFLWAILQNRQEMANYFWAMGPEAVAAALVGCKIMKEMAHLATEAESARSMKNAKYEQFAMDLFSECYSNSEDRAYSLLVRKTCCWSKATVLNIATLAEAKCFFAHDGVQALLTKVWWGAMRTDTSISRLVLTFFIPPLVWTSLIKFNPEEQVSKDEGEPFAELDSLETEQALLLTDGDPVAGEGSAETAARSCSATFIRVVLRRWNRFWSAPVTVFMGNVIMYFAFLILFSYVLLLDFRPPPPYGPSAAEIILYFWVFTLVLEEIRQSFFTDEDMSILKKMKLYVEDNWNKCDMVAISLFVVGLSCRMAMSTYEAGRTVLALDFMVFTLRLIHIFAIHKQLGPKIIIVERMIKDVFFFLFFLSVWLIAYGVTTQALLHPNDPRIDWVFRRALYRPYLHIFGQIPLEEIDAAKMPDDNCTTDVQEIILGTLPPCPNIYANWLVILLLVIYLLVTNVLLLNLLIAMFSYTFQVVQENADIFWKFQRYNLIVEYHSRPALAPPFIIISHITQALLS-FIKKTENTQDLLERELPSGLDQKLMTWETVQKENYLAKLEHEHRESSGERLRYTSSKVQTLLRMVGGFKDQEKRMATVETEVRYCGEVLSWIAECFHKSTLKCDRDAPKAPRSIAGSSRDQQPQGAKRQQPAGHPAYGTDKKLPFIDH", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .: . : . *:::* * .:.*.***:*.*.. *: ::::* :* *..*:***:*:* :. :*.****.*******************.*:.*:::::*************.*:****:*:*. . : :* :* .: * * ** :: *.: .**.* ******: .. * . *::: : **** **:*****..*:********:*:* *::: : :::: *****.****:**:*.:*:.: ..:.:: : :.** . : *. **:*:*.* * *****:* **:. :***************:*::.**:**********:**********.***:*.: ****** :***.:**:*******.*.:: :********:** *** *.**. ** :*::* : ** :. : .* *::****:******.*:*:****. . * : .** * *:.::.*.*********:**** ***.****** *.*****..***:***:** .*** **: ::****::*:*******.*** **::****:. .**::* *::** *:**.*********:**::*** * :.*.* **: :* *.*::*.**.*. *: : * : : ***: *:: * . : .* * . .. .:* **.:**.******:***:******:**:****:****** ***..*: ***************.***:** ::**:.*** *********** **:**::*** *.:********:************************:****:**************:************:* *::*:***.******:*******:*** *:: **: : ::* ..**.:*********** :********:*************** ***:*******:****** *********::**:: .* * *::::.:: ***:**. :***::*********:*:.:*:.:*:*. * ** *: :*: : : :**:::****: :*:: .** ::* ::: : . . : . * :: .: . :* * .* ", "identical_positions": 623, "similar_positions": 311, "identity": "52.09%" }, { "cls_id": "homologset.agr.MGI:1861721", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9D6J4-1", "uniprot_id": "NECA3_MOUSE", "id": "Q9D6J4-1", "name": "N-terminal EF-hand calcium-binding protein 3", "aln": "-MACAGLLTVCLLGPPAPQ----QPRHS--AP---AAGHALFQDVFRRADKNDDGKLSFEEFQNYFADGVLSSAELRELFSGIDDHLTDNLETEKLCDYFSTHLGVYRPVLAALESLNRAVLTAMDTTKLEYEQASKVDQFVTRFLLRETVNQLQALQTSLEGASDTLEAQAHGQRLDEETIKAQSRPCGSRRAGRRALRSISWSPSWS-PGSSDTGRSSEAEQQWRLQVNRLQELIDQLECK----------------------------------APRLEPTHEEDLTKGFDSHILVAQRQVQVAEDALQDFHRALCCYMNFTGAQSHCLHVSAQKMLDNAAFTLYEFWQDEASWRRHQQSPCSKAFQRTLIDHLQAPDTLTTVFFPASWWIMNNN", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q96P71-1", "uniprot_id": "NECA3_HUMAN", "id": "Q96P71-1", "name": "N-terminal EF-hand calcium-binding protein 3", "aln": "-MACAGLLTVCLLRPPAPQPQPQTPRHPQLAPDPGPAGHTLFQDVFRRADKNDDGKLSFEEFQNYFADGVLSLGELQELFSGIDGHLTDNLETEKLCDYFSEHLGVYRPVLAALESLNRAVLAAMDATKLEYERASKVDQFVTRFLLRETVSQLQALQSSLEGASDTLEAQAHGWRSDAESVEAQSRLCGSRRAGRRALRSVSRSSTWS-PGSSDTGRSSEAEMQWRLQVNRLQELIDQLECKVRAVGPGPHKGGPSWYPPEPGPCWRPGPHSVPSQAPRLEPLREEDLAKGPDLHILMAQRQVQVAEEGLQDFHRALRCYVDFTGAQSHCLHVSAQKMLDGASFTLYEFWQDEASWRRHQQSPGSKAFQRILIDHLRAPDTLTTVFFPASWWIMNNN", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M2BG34-1", "uniprot_id": "A0A8M2BG34_DANRE", "id": "A0A8M2BG34-1", "name": "", "aln": "MLACAEMITMCLQSAKREHLRSKQHQMQHQMLDS-VHGLSIFHDIFRRADKNDDGKLSFEEFKAYFADGILTTDELRELFYSIDGRQTNNLDTDKLSDYFSQHLGEYLDVLSALEKLNVAVLKAMDKTKEDYQGSSVLGQFVTRFMLRETSSQLLSLQMSLQCAMEAVEAQSSTTPVEVKVPEHLVIQKNNRRCGRRVQKNMCLSPTDPYSGILTTGVTVDTDEHWCSQINRLQQLIDKLECQ----------------------------------SPKLEPLKEDTLASTYKSNILLVQRQMSVMENDLEEFQKALKSYADTTANQNDNLHVSIQKLPEKSCYIIYEFWQDRISWMSYLQSDASKMFQRCIIDMLEDPEIVSTMLMPASWWIMTNN", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :*** ::*:** . : : * ::*:*:*****************: *****:*: **:*** .**.: *:**:*:**.**** *** * **:***.** *** *** ** :*: :* :.******:**** .** :** **: * :::***: : : : ..**.***. :.:. *.: . .* ** : ::: :* *:****:***:***: :*:*** :*: *:. . :**:.***:.* *: *::*::** .* : *. *.. **** **: : :.: :******. ** : ** ** *** :** *. *: ::*:::*******.**", "identical_positions": 166, "similar_positions": 100, "identity": "41.71%" }, { "cls_id": "homologset.agr.MGI:1861722", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9JHW9-1", "uniprot_id": "AL1A3_MOUSE", "id": "Q9JHW9-1", "name": "Retinaldehyde dehydrogenase 3", "aln": "-MATTNGAVENGQPD--------------GKPPALPRPIRNLEVKFTKIFINNDWHESKSGRKFATYNPSTLEKICEVEEGDKPDVDKAVEAAQAAFQRGSPWRRLDALSRGQLLHQLADLVERDRAILATLETMDTGKPFLHAFFVDLEGCIKTFRYFAGWADKIQGRTIPTDDNVVCFTRHEPIGVCGAITPWNFPLLMLAWKLAPALCCGNTVVLKPAEQTPLTALYLASLIKEVGFPPGVVNIVPGFGPTVGAAISSHPQINKIAFTGSTEVGKLVREAASRSNLKRVTLELGGKNPCIVCADADLDLAVECAHQGVFFNQGQCCTAASRVFVEEQVYGEFVRRSVEFAKK-RPVGDPFDAKTEQGPQIDQKQFDKILELIESGKKEGAKLECGGSAMEDRGLFIKPTVFSDVTDNMRIAKEEIFGPVQPILKFKNLEEVIKRANSTDYGLTAAVFTKNLDKALKLAAALESGTVWINCYNAFYAQAPFGGFKMSGNGRELGEYALAEYTEVKTVTIKLEEKNP", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8K4D8-1", "uniprot_id": "AL1A3_RAT", "id": "Q8K4D8-1", "name": "Retinaldehyde dehydrogenase 3", "aln": "-MATANGAVENGQPD--------------GKPPALPRPIRNLEVKFTKIFINNDWHEPKSGRKFATYNPSTLEKICEVEEGDKPDVDKAVEAAQAAFQRGSPWRRLDALSRGQLLHQLADLIERDRAILATLETMDTGKPFLHAFFVDLEGCIKTFRYFAGWADKIQGRTIPTDDNVMCFTRHEPIGVCGAITPWNFPLLMLAWKLAPALCCGNTVVLKPAEQTPLTALYLASLIKEVGFPPGVVNIVPGFGPTVGAAISSHPQINKIAFTGSTEVGKLVKEAASRSNLKRVTLELGGRNPCIVCADADLDLAVECAHQGVFFNQGQCCTAASRVFVEEQVYGEFVRRSVEFAKK-RPVGDPFDAKTEQGPQIDQKQFDKILELIESGKKEGAKLECGGSAMEDRGLFIKPTVFSDVTDNMRIAKEEIFGPVQPILKFKNLEEVIKRANSTDYGLTAAVFTKNLDKALKLASALESGTVWVNCYNAFYAQAPFGGFKMSGNGRELGEYALAEYTEVKTVTIKLDEKNP", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P47895-1", "uniprot_id": "AL1A3_HUMAN", "id": "P47895-1", "name": "Retinaldehyde dehydrogenase 3", "aln": "-MATANGAVENGQPD--------------RKPPALPRPIRNLEVKFTKIFINNEWHESKSGKKFATCNPSTREQICEVEEGDKPDVDKAVEAAQVAFQRGSPWRRLDALSRGRLLHQLADLVERDRATLAALETMDTGKPFLHAFFIDLEGCIRTLRYFAGWADKIQGKTIPTDDNVVCFTRHEPIGVCGAITPWNFPLLMLVWKLAPALCCGNTMVLKPAEQTPLTALYLGSLIKEAGFPPGVVNIVPGFGPTVGAAISSHPQINKIAFTGSTEVGKLVKEAASRSNLKRVTLELGGKNPCIVCADADLDLAVECAHQGVFFNQGQCCTAASRVFVEEQVYSEFVRRSVEYAKK-RPVGDPFDVKTEQGPQIDQKQFDKILELIESGKKEGAKLECGGSAMEDKGLFIKPTVFSEVTDNMRIAKEEIFGPVQPILKFKSIEEVIKRANSTDYGLTAAVFTKNLDKALKLASALESGTVWINCYNALYAQAPFGGFKMSGNGRELGEYALAEYTEVKTVTIKLGDKNP", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P46367-1", "uniprot_id": "ALDH4_YEAST", "id": "P46367-1", "name": "Potassium-activated aldehyde dehydrogenase, mitochondrial", "aln": "MFSRSTLCLKTSASSIGRLQLRYFSHLPMTVPIKLPNGLEYEQP--TGLFINNKFVPSKQNKTFEVINPSTEEEICHIYEGREDDVEEAVQAADRAFSNGS-WNGIDPIDRGKALYRLAELIEQDKDVIASIETLDNGK-AISSSRGDVDLVINYLKSSAGFADKIDGRMIDTGRTHFSYTKRQPLGVCGQIIPWNFPLLMWAWKIAPALVTGNTVVLKTAESTPLSALYVSKYIPQAGIPPGVINIVSGFGKIVGEAITNHPKIKKVAFTGSTATGRHIYQ-SAAAGLKKVTLELGGKSPNIVFADAELKKAVQNIILGIYYNSGEVCCAGSRVYVEESIYDKFIEEFKAASES-IKVGDPFDESTFQGAQTSQMQLNKILKYVDIGKNEGATLITGGERLGSKGYFIKPTVFGDVKEDMRIVKEEIFGPVVTVTKFKSADEVINMANDSEYGLAAGIHTSNINTALKVADRVNAGTVWINTYNDFHHAVPFGGFNASGLGREMSVDALQNYLQVKAVRAKLDE---", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P54115-1", "uniprot_id": "ALDH6_YEAST", "id": "P54115-1", "name": "Magnesium-activated aldehyde dehydrogenase, cytosolic", "aln": "---MTKLHFDTAEP----------------VKITLPNGLTYEQP--TGLFINNKFMKAQDGKTYPVEDPSTENTVCEVSSATTEDVEYAIECADRAFHDTE-WATQDPRERGRLLSKLADELESQIDLVSSIEALDNGK-TLALARGDVTIAINCLRDAAAYADKVNGRTINTGDGYMNFTTLEPIGVCGQIIPWNFPIMMLAWKIAPALAMGNVCILKPAAVTPLNALYFASLCKKVGIPAGVVNIVPGPGRTVGAALTNDPRIRKLAFTGSTEVGKSVAVDSSESNLKKITLELGGKSAHLVFDDANIKKTLPNLVNGIFKNAGQICSSGSRIYVQEGIYDELLAAFKAYLETEIKVGNPFDKANFQGAITNRQQFDTIMNYIDIGKKEGAKILTGGEKVGDKGYFIRPTVFYDVNEDMRIVKEEIFGPVVTVAKFKTLEEGVEMANSSEFGLGSGIETESLSTGLKVAKMLKAGTVWINTYNDFDSRVPFGGVKQSGYGREMGEEVYHAYTEVKAVRIKL-----", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :. .... . **. : : * :****.: .:..:.: . :*** : :*.: .. **: *::.*: ** . * *. .**: * :**: :* : ::::*::*.** : *: *. :: *.:***::*: * *. . :* :*:**** * *****::* .**:**** **. :**.* ***.***... :.*:*.**:***.* * ** *::..*:*.*:****** .*: : :: :.**::******:.. :* **::. :: *:: * *: * :.**::*:* :*.::: :. **:*** . **. .: *::.*:: :: **:***.: **. : .:* **:**** :*.::***.******** .: ***. :* :: **.:::** :.: *..:...**:* :::****:* ** : .****.: ** ***:. . * :**:* ** ", "identical_positions": 179, "similar_positions": 178, "identity": "33.9%" }, { "cls_id": "homologset.agr.MGI:1861723", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q95029-1", "uniprot_id": "CATL1_DROME", "id": "Q95029-1", "name": "Cathepsin L1", "aln": "MNHLGVFETRFRPRTRHKSQRAQLIPEQITMRTAVLLPLLALLAVAQAVSFADVVMEEWHTFKLEHRKNYQDETEERFRLKIFNENKHKIAKHNQRFAEGKVSFKLAVNKYADLLHHEFRQLMNGFNYTLHKQLRAADESFKGVTFISPAHVTLPKSVDWRTKGAVTAVKDQGHCGSCWAFSSTGALEGQHFRKSGVLVSLSEQNLVDCSTKYGNNGCNGGLMDNAFRYIKDNGGIDTEKSYPYEAIDDS-CHFNKGTVGATDRGFTDIPQGDEKKMAEAVATVGPVSVAIDASHESFQFYSEGVYNEPQCDAQNLDHGVLVVGFG---TDESGEDYWLVKNSWGTTWGDKGFIKMLRNKENQCGIASASSYPLV", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "A0A8M1NEU9-1", "uniprot_id": "A0A8M1NEU9_DANRE", "id": "A0A8M1NEU9-1", "name": "", "aln": "-------------------------------MMFALLVTLCISAVFAASSIDIQLDDHWNSWKSQHGKSYHEDVEVG-RRMIWEENLKKIEQHNFEYSYGNHTFKMGMNQFGDMTNEEFRQAMNGYKHDPNRTS-------QGPLFMEPSFFAAPQQVDWRQRGYVTPVKDQKQCGSCWSFSSTGALEGQLFRKTGKLISMSEQNLVDCSRPQGNQGCNGGLMDQAFQYVKENKGLDSEQSYPYLARDDLPCRYDPRFNVAKITGFVDIPRGNELALMNAVAAVGPVSVAIDASHQSLQFYQSGIYYERACSSSRLDHAVLVVGYGYQGADVAGNRYWIVKNSWSDKWGDKGYIYMAKDKNNHCGVATTASYPLM", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9JIA9-1", "uniprot_id": "CATR_MOUSE", "id": "Q9JIA9-1", "name": "Cathepsin R", "aln": "------------------------------MAAVVFIAFLYLGVASGVPVLDSSLDAEWQDWKIKYNKSYSLK-EEKLKRVVWEEKLKMIKLHNRENSLGKNGFTMKMNEFGDQTDEEFRKMMIEISVWTHREG--------KSIMKREAGSILPKFVDWRKKGYVTPVRRQGDCDACWAFAVTGAIEAQAIWQTGKLTPLSVQNLVDCSKPQGNNGCLGGDTYNAFQYVLHNGGLESEATYPYEGKDGP-CRYNPKNSKAEITGFVSLPQSED-ILMAAVATIGPITAGIDASHESFKNYKGGIYHEPNCSSDTVTHGVLVVGYGFKGIETDGNHYWLIKNSWGKRWGIRGYMKLAKDKNNHCGIASYAHYPTI", "tax_id": 10090, "tax_name": "Mouse" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .:: * : .. . : : .*: :* :: *.* . * : :::*: : * ** . : *: *.: :*::.* ..***: * . :: : : *: **** :* **.*: * .*.:**:*: ***:*.* : ::* * .:* ******* **:** ** :**:*: .* *:::* :*** . *. *::: * **..:*:.:: : ***::**::..*****:*:: *. *:* * *.:. : *.*****:* : *: **::****. ** :*:: : ::*:*:**:*: : ** :", "identical_positions": 108, "similar_positions": 111, "identity": "28.8%" }, { "cls_id": "homologset.agr.MGI:1861727", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O60832-1", "uniprot_id": "DKC1_HUMAN", "id": "O60832-1", "name": "H/ACA ribonucleoprotein complex subunit DKC1", "aln": "-------MADAEVIILPKKHKKKKERKSLPEEDVAEIQHAEEFLIKPESKVAKLDTSQWPLLLKNFDKLNVRTTHYTPLACGSNPLKREIGDYIRTGFINLDKPSNPSSHEVVAWIRRILRVEKTGHSGTLDPKVTGCLIVCIERATRLVKSQQSAGKEYVGIVRLHNAIEGGTQLSRALETLTGALFQRPPLIAAVKRQLRVRTIYESKMIEYDPERRLGIFWVSCEAGTYIRTLCVHLGLLLGVGGQMQELRRVRSGVMSEKDHMVTMHDVLDAQWLYDNHKDESYLRRVVYPLEKLLTSHKRLVMKDSAVNAICYGAKIMLPGVLRYEDGIEVNQEIVVITTKGEAICMAIALMTTAVISTCDHGIVAKIKRVIMERDTYPRKWGLGPKASQKKLMIKQGLLDKHGKPTDSTPATWKQEYVDYSESAKKEVVAEVVKAPQVVAEAAKTAKRKRESESESDETPPAAPQLIKKEKKKSKKDKKAKAGLESGAEPGDGDSDTTKKKKKKKKAKEVELVSE", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9ESX5-1", "uniprot_id": "DKC1_MOUSE", "id": "Q9ESX5-1", "name": "H/ACA ribonucleoprotein complex subunit DKC1", "aln": "-------MADAEVITFPKKHKKKKDRKPLQEDDVAEIQHAEEFLIKPESKVAQLDTSQWPLLLKNFDKLNVRTAHYTPLPCGSNPLKREIGDYIRTGFINLDKPSNPSSHEVVAWIRRILRVEKTGHSGTLDPKVTGCLIVCIERATRLVKSQQSAGKEYVGIVRLHNAIEGGTQLSRALETLTGALFQRPPLIAAVKRQLRVRTIYESKMIEYDPERRLGIFWVSCEAGTYIRTLCVHLGLLLGVGGQMQELRRVRSGVMSEKDHMVTMHDVLDAQWLYDNHKDESYLRRVVYPLEKLLTSHKRLVMKDSAVNAICYGAKIMLPGLLRYEDGIEVNQEIVVITTKGEAICMAIALMTTAVISTCDHGIVAKIKRVIMERDTYPRKWGLGPKASQKKMMIKQGLLDKHGKPTDNTPATWKQDYIDYSDSGKNTLVTEAVQAPQLAAEAVNVIKRKRDSESESDETP-TVPQLKEKKK---KKDKKPKTVLESGGETGDGDNDTTKKKKKKK-VKVVEEMSE", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0ABK0LZH8-1", "uniprot_id": "A0ABK0LZH8_RAT", "id": "A0ABK0LZH8-1", "name": "H/ACA ribonucleoprotein complex subunit DKC1", "aln": "MARRPPPMARPFLSPLTSCHPPTSCHPPPPPQ---EIQHAEDFLIKPESKAAQLDTSQWPLLLKNFDRLNVRTTHYTPIPCGSNPLKREIGEYVRTGFINLDKPSNPSSHEVVAWIRRILRVEKTGHSGTLDPKVTGCLIVCIERATRLVKSQQSAGKEYVGVVRLHNAIEGTAQLSRALETLTGALFQRPPLIAAVKRQLRVRTIYESRVVEYDPERRLG------EAG-------------VTVG--SWARGRVRS--------------------------------------------------RGSPVGGGSWSGNLDLSGKCDLFN-----------------PCL-------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P33322-1", "uniprot_id": "CBF5_YEAST", "id": "P33322-1", "name": "H/ACA ribonucleoprotein complex subunit CBF5", "aln": "-------------------------------------MSKEDFVIKPEAAGASTDTSEWPLLLKNFDKLLVRSGHYTPIPAGSSPLKRDLKSYISSGVINLDKPSNPSSHEVVAWIKRILRCEKTGHSGTLDPKVTGCLIVCIDRATRLVKSQQGAGKEYVCIVRLHDALKDEKDLGRSLENLTGALFQRPPLISAVKRQLRVRTIYESNLIEFDNKRNLGVFWASCEAGTYMRTLCVHLGMLLGVGGHMQELRRVRSGALSENDNMVTLHDVMDAQWVYDNTRDESYLRSIIQPLETLLVGYKRIVVKDSAVNAVCYGAKLMIPGLLRYEEGIELYDEIVLITTKGEAIAVAIAQMSTVDLASCDHGVVASVKRCIMERDLYPRRWGLGPVAQKKKQMKADGKLDKYGRVNENTPEQWKKEYVPLDNAEQSTSSSQETKETEEEPKKAKEDSLIKEVETEKEEVKEDDSKKEKKEKK-DKKEKKEKKEKKDKKEKKEKKEKKRKSEDGDSEEKKSKKSKK", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "O44081-1", "uniprot_id": "DKC1_DROME", "id": "O44081-1", "name": "H/ACA ribonucleoprotein complex subunit 4", "aln": "-------MADVEVR--KEKKKKKIKEEPLDGDDIGTLQKQGNFQIKPSSKIAELDTSQWPLLLKNFDKLNIRSNHYTPLAHGSSPLNRDIKEYMKTGFINLDKPSNPSSHEVVAWIKKILKVEKTGHSGTLDPKVTGCLIVCIDRATRLVKSQQSAGKEYVAIFKLHGAVESVAKVRQGLEKLRGALFQRPPLISAVKRQLRVRTVYDSKLLDYDETRNMGVFWVSCEAGSYIRTMCVHLGLVLGVGGQMLELRRVRSGIQSERDGMVTMHDVLDAMWLYENHKDESMLRRVIKPLEGLLVNHKRIIMKDSSVNAVCYGAKITLPGVLRYEDGIEIDQEIVICTTKGEAICLAIALMTTATMASCDHGVVAKIKRVIMERDTYPRKWGLGPKASAKKALIAAGKLDKFGRPNENTPKEWLTGYVDYN-AKKPAAQEVSPTNGSSEPSKRKLSTSSVEETAAAAVSEETPSKDKKKKKKKHKGDEEAPEAAEEEAEPVEKEKKKKKKKDKDRDRDEAQE---", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :* ***.: *. ***:*********:* :*: ****:. **.**:*:: .*: :*.******************::**: *********************:**********.****** :.:**.*::. .: :.**.* **********:**********:*:*.::::* *.:* *** : ** **** :.*.*.. .:..:: :.* : .: ", "identical_positions": 130, "similar_positions": 62, "identity": "24.95%" }, { "cls_id": "homologset.agr.MGI:1861728", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "F7FIK1-1", "uniprot_id": "F7FIK1_RAT", "id": "F7FIK1-1", "name": "NEDD4-like E3 ubiquitin-protein ligase WWP1", "aln": "MSSLTEEIASSSSSYPQCLEQFLVHKFQFWALQTCFSYYSICHNQGEFWDMATASPRSDTS-DNHSGRLQLKVTVSSAKLKRKKNWFGTAIYTEVIVDGEIK-KTAKSSSSSNPKWDEQLIVNVAPQTTLEFRVWSHHTLKADALLGKATVDLKQVLLTHNRKLEKVKEQLKLSLENK--NGIVQTGELTVVLDGLVIEPEAVTNRSSSPPIEIQQNGDAVHENGDPLTRTTPRLAVEGTIGIDNHVSTSTVVPSSCCSHIVNGENTPSSPPQVATRPQNTPAPKPLTSEPTSDTVNGESSS-VLADSTSAMGTSLPSEDSTSTSNCTSTTVQEPPVQEPPASSEHSECIPSASAEVGPEARSLIDPD-SDSRNNSGFD--KVRQPEGCVEPLRPQSGNTNTESLPSGWEQRKDPHGRTYYVDHNTRTTTWERPQPLPPGWERRVDDRGRVYYVDHNTRTTTWQRPTMESVRNFEQWQSQRNQLQGAMQQFNQRYLYS----------ASMLAAENDPYGPLPPGWEKRVDSTDRVYFVNHNTKTTQWEDPRTQG----LPNEEPLPEGWEIRYTREGVRYFVDHNTRTTTFKDPRNGKSSVTKG--GPQIAYERSFRWKLAHFRYLCQSNALPSHVKINVSRQTLFEDSFQQIMALKPYDLRRRLYVIFRGEEGLDYGGLAREWFFLLSHEVLNPMYCLFEYAGKNNYCLQINPASTINPDHLSYFCFIGRFIAMALFHGKFIDTGFSLPFYKRMLSKKLTIKDLESIDTEFYNSLIWIRDNNIEECGLEMYFSVDMEILGKVTSHDLKLGGSNILVTEENKDEYIGLMTEWRFSRGVQEQTKAFLDGFNEVVPLQWLQYFDEKELEVMLCGMQEVDLADWQRNTVYRHYTRNSKQIIWFWQFVKETDNEVRMRLLQFVTGTCRLPLGGFAELMGSNGPQKFCIEKVGKDTWLPRSHTCFNRLDLPPYKSYEQLKEKLLFAIEETEGFGQE", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8BZZ3-1", "uniprot_id": "WWP1_MOUSE", "id": "Q8BZZ3-1", "name": "NEDD4-like E3 ubiquitin-protein ligase WWP1", "aln": "--------------------------------------------------MATASPRSDTS-DIHSGRLQLKVTVSSAKLKRKKNWFGTAIYTEVIVDGEVK-KTAKSSSSSNPKWDEQLIVNVTPQTTLEFRVWSHHTLKADALLGKATVDLKQVLLTHNRKLEKVKEQLKLSLENK--NGIVQTGELTVVLDGLVIEQEPVTNRSSSPPIEIQQNGDALHENGDPATRTTPRLPVEGTIGIDNHVSTNTVVPNSCCSHVVNGENTPSSPSQVAARPKNAPAPKPVTSAPTSDTVNGESSS-VLADNTSTMGTLLPSEDTTSTSNCTSTTTQEPPVQEPPASSEHSECIPSASAEVGPEARSLIDPD-SDSRNNSVFD--KVRQPEGCVEPLRPQSGNTNTEALPSGWEQRKDPHGRTYYVDHNTRTTTWERPQPLPPGWERRVDDRGRVYYVDHNTRTTTWQRPTMESVRNFEQWQSQRNQLQGAMQQFNQRYLYS----------ASMLAAENDPYGPLPPGWEKRVDSTDRVYFVNHNTKTTQWEDPRTQG----LPNEEPLPEGWEIRYTREGVRYFVDHNTRTTTFKDPRNGKSSVTKG--GPQIAYERSFRWKLAHFRYLCQSNALPSHVKINVSRQTLFEDSFQQIMALKPYDLRRRLYVIFRGEEGLDYGGLAREWFFLLSHEVLNPMYCLFEYAGKNNYCLQINPASTINPDHLSYFCFIGRFIAMALFHGKFIDTGFSLPFYKRMLSKKLTIKDLESIDTEFYNSLIWIRDNNIEECGLEMYFSVDMEILGKVTSHDLKLGGSNILVTEENKDEYIGLMTEWRFSRGVQEQTKAFLDGFNEVVPLQWLQYFDEKELEVMLCGMQEVDLADWQRNTVYRHYTRNSKQIIWFWQFVKETDNEVRMRLLQFVTGTCRLPLGGFAELMGSNGPQKFCIEKVGKDTWLPRSHTCFNRLDLPPYKSYEQLKEKLLFAIEETEGFGQE", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9H0M0-1", "uniprot_id": "WWP1_HUMAN", "id": "Q9H0M0-1", "name": "NEDD4-like E3 ubiquitin-protein ligase WWP1", "aln": "--------------------------------------------------MATASPRSDTS-NNHSGRLQLQVTVSSAKLKRKKNWFGTAIYTEVVVDGEIT-KTAKSSSSSNPKWDEQLTVNVTPQTTLEFQVWSHRTLKADALLGKATIDLKQALLIHNRKLERVKEQLKLSLENK--NGIAQTGELTVVLDGLVIEQENITNCSSSPTIEIQENGDALHENGEPSARTTARLAVEGTNGIDNHVPTSTLVQNSCCSYVVNGDNTPSSPSQVAARPKNTPAPKPLASEPADDTVNGESSSFAPTDNASVTGTPVVSEENALSPNCTSTTVEDPPVQEILTSSENNECIPSTSAELESEARSILEPDTSNSRSSSAFEAAKSRQPDGCMDPVRQQSGNANTETLPSGWEQRKDPHGRTYYVDHNTRTTTWERPQPLPPGWERRVDDRRRVYYVDHNTRTTTWQRPTMESVRNFEQWQSQRNQLQGAMQQFNQRYLYS----------ASMLAAENDPYGPLPPGWEKRVDSTDRVYFVNHNTKTTQWEDPRTQG----LQNEEPLPEGWEIRYTREGVRYFVDHNTRTTTFKDPRNGKSSVTKG--GPQIAYERGFRWKLAHFRYLCQSNALPSHVKINVSRQTLFEDSFQQIMALKPYDLRRRLYVIFRGEEGLDYGGLAREWFFLLSHEVLNPMYCLFEYAGKNNYCLQINPASTINPDHLSYFCFIGRFIAMALFHGKFIDTGFSLPFYKRMLSKKLTIKDLESIDTEFYNSLIWIRDNNIEECGLEMYFSVDMEILGKVTSHDLKLGGSNILVTEENKDEYIGLMTEWRFSRGVQEQTKAFLDGFNEVVPLQWLQYFDEKELEVMLCGMQEVDLADWQRNTVYRHYTRNSKQIIWFWQFVKETDNEVRMRLLQFVTGTCRLPLGGFAELMGSNGPQKFCIEKVGKDTWLPRSHTCFNRLDLPPYKSYEQLKEKLLFAIEETEGFGQE", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9Y0H4-1", "uniprot_id": "SUDX_DROME", "id": "Q9Y0H4-1", "name": "E3 ubiquitin-protein ligase Su(dx)", "aln": "MADGNGLPAGAASGG--------------------MEAGQTVNGAGSASPTPTSSSGAGASGSANQGYHQLSVTIEEASLR-NNGFLKPNPYVELLIDSKSKRKTDLVKNSYLPKWNEEFTVLITPNSTLHFKVLDHSSFRKDAMLGERIINLAHILQHYNGRCEFLELTIDLFVTSKSDNRQTKSGELVAILNGLKLD----MSKLQIQPVAGQQNGNPPVQAVNPSVVSDA--AAGRSCMIYGGVRARMRLRSSSGN--SNGGETRSPLPNGGGDHRRSTQAPPVWEQQQQQSQNQQQPLRMVNGSGAAVPQTAPYPQQPPAP-----ALARPLTQVYGALPEN---TQPAAVYLPAGGGAAVGPP---GVAGPPIEQPGVGLPVSQSTDPQLQTQPADDEPLPAGWEIRLDQYGRRYYVDHNTRSTYWEKPTPLPPGWEIRKDGRGRVYYVDHNTRKTTWQRPNSERLMHFQHWQGQR---AHVVSQGNQRYLYSQQQQQPTAVTAQVTQDDEDALGPLPDGWEKKIQSDNRVYFVNHKNRTTQWEDPRTQGQEVSLINEGPLPPGWEIRYTAAGERFFVDHNTRRTTFEDPRPGAPKGAKGVYGVPRAYERSFRWKLSQFRYLCQSNALPSHIKITVTRQTLFEDSYHQIMRLPAYELRRRLYIIFRGEEGLDYGGVSREWFFLLSHEVLNPMYCLFEYANKNNYSLQINPASYVNPDHLQYFKFIGRFIAMALYHGRFIYSGFTMPFYKRMLNKKLTIKDIETIDPEFYNSLIWVKDNNIDECGLELWFSVDFEVLGQIIHHELKENGEKERVTEENKEEYITLMTEWRMTRGIEQQTKTFLEGFNEVVPLEWLKYFDERELELILCGMQDVDVEDWQRNTIYRHYNRNSKQVVWFWQFVRETDNEKRARLLQFVTGTCRVPVGGFAELMGSNGPQRFCIEKVGKETWLPRSHTCFNRLDLPPYKSYDQLVEKLTFAIEETEGFCQE", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .*:*. :.:* . :.* **.**:..*.*: ::.:: . *.*:::*.: . ** ..* ***:*:: * ::*::**.*:* .* ::: **:**: ::* : * :* : * :: :.* : .* * .::***..:*:** :: . . .: *:**:. : :* . : . .. : * . * : : .*. . ** :* *. .: . :.:. . *: . .:: * :.. .. :. : . :. : * .* : .*: .::. : . . : : * . .. :: * . : *: :: *.**:*** * * :** ********:* **:* ******* * *.* **********.******. * : :*::**.** .:.* ******* *.: ::*. **** ****:::* :*******:.:*********** * ** *** ******* * *:******* ***:*** * .. :** * ****.*****::*************:**.*:********::*** * .*:******:************::**********************.****.******* :*****.** **********:**:** :**::*******.*******:*:**.********::****:*****::****:*:**:: *:** .*.: ******:*** ******::**:::***:**:********:**:****:***::*****:**: ******:****.*****::******:***** * ***********:*:*************:********:*********************:** *** ********* **", "identical_positions": 486, "similar_positions": 233, "identity": "48.99%" }, { "cls_id": "homologset.agr.MGI:1861729", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9QYJ4-1", "uniprot_id": "ABCB9_RAT", "id": "Q9QYJ4-1", "name": "ABC-type oligopeptide transporter ABCB9", "aln": "MRLWKAVVVTLAFVSMDVGVTTAIYAFSHLDRSLLEDIRHFNIFDSVLDLWAACLYRSCLLLGATIGVAKNSALGPRRLRASWLVITLVCLFVGIYAMAKLLLFSEVRRPIRDPWFWALFVWTYISLAASFLLWGLLATVRPDAEALEPGN----EGFHGEGGAPAEQ---------ASGATLQKLLSYTKPDVAFLVAASFFLIVAALGETFLPYYTGRAIDSIVIQKSMDQFTTAVVVVCLLAIGSSLAAGIRGGIFTLVFARLNIRLRNCLFRSLVSQETSFFDENRTGDLISRLTSDTTMVSDLVSQNINIFLRNTVKVTGVVVFMFSLSWQLSLVTFMGFPIIMMVSNIYGKYYKRLSKEVQSALARASTTAEETISAMKTVRSFANEEEEAEVFLRKLQQVYKLNRKEAAAYMSYVWGSGLTLLVVQVSILYYGGHLVISGQMSSGNLIAFIIYEFVLGDCMESVGSVYSGLMQGVGAAEKVFEFIDRQPTMVHDGRLAPDHLEGRVDFENVTFTYRTRPHTQVLQNVSFSLSPGKVTALVGPSGSGKSSCVNILENFYPLQGGRVLLDGEPIGAYDHKYLHRVISLVSQEPVLFARSITDNISYGLPTVPFEMVVEAAQKANAHGFIMELQDGYSTETGEKGAQLSGGQKQRVAMARALVRNPPVLILDEATSALDAESEYLIQQAIHGNLQRHTVLIIAHRLSTVERAHLIVVLDKGRVVQQGTHQQLLAQGGLYAKLVQRQMLGLEHPLDYTAG--------------HKEPPSNTEHKA--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9JJ59-1", "uniprot_id": "ABCB9_MOUSE", "id": "Q9JJ59-1", "name": "ABC-type oligopeptide transporter ABCB9", "aln": "MRLWKAVVVTLAFVSTDVGVTTAIYAFSHLDRSLLEDIRHFNIFDSVLDLWAACLYRSCLLLGATIGVAKNSALGPRRLRASWLVITLVCLFVGIYAMAKLLLFSEVRRPIRDPWFWALFVWTYISLAASFLLWGLLATVRPDAEALEPGN----EGFHGEGGAPAEQ---------ASGATLQKLLSYTKPDVAFLVAASFFLIVAALGETFLPYYTGRAIDSIVIQKSMDQFTTAVVVVCLLAIGSSLAAGIRGGIFTLVFARLNIRLRNCLFRSLVSQETSFFDENRTGDLISRLTSDTTMVSDLVSQNINIFLRNTVKVTGVVVFMFSLSWQLSLVTFMGFPIIMMVSNIYGKYYKRLSKEVQSALARASTTAEETISAMKTVRSFANEEEEAEVFLRKLQQVYKLNRKEAAAYMSYVWGSGLTLLVVQVSILYYGGHLVISGQMSSGNLIAFIIYEFVLGDCMESVGSVYSGLMQGVGAAEKVFEFIDRQPTMVHDGSLAPDHLEGRVDFENVTFTYRTRPHTQVLQNVSFSLSPGKVTALVGPSGSGKSSCVNILENFYPLQGGRVLLDGKPIGAYDHKYLHRVISLVSQEPVLFARSITDNISYGLPTVPFEMVVEAAQKANAHGFIMELQDGYSTETGEKGAQLSGGQKQRVAMARALVRNPPVLILDEATSALDAESEYLIQQAIHGNLQRHTVLIIAHRLSTVERAHLIVVLDKGRVVQQGTHQQLLAQGGLYAKLVQRQMLGLEHPLDYTAS--------------HKEPPSNTEHKA--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9NP78-1", "uniprot_id": "ABCB9_HUMAN", "id": "Q9NP78-1", "name": "ABC-type oligopeptide transporter ABCB9", "aln": "MRLWKAVVVTLAFMSVDICVTTAIYVFSHLDRSLLEDIRHFNIFDSVLDLWAACLYRSCLLLGATIGVAKNSALGPRRLRASWLVITLVCLFVGIYAMVKLLLFSEVRRPIRDPWFWALFVWTYISLGASFLLWWLLSTVRPGTQALEPGAATEAEGFPGSGRPPPEQ---------ASGATLQKLLSYTKPDVAFLVAASFFLIVAALGETFLPYYTGRAIDGIVIQKSMDQFSTAVVIVCLLAIGSSFAAGIRGGIFTLIFARLNIRLRNCLFRSLVSQETSFFDENRTGDLISRLTSDTTMVSDLVSQNINVFLRNTVKVTGVVVFMFSLSWQLSLVTFMGFPIIMMVSNIYGKYYKRLSKEVQNALARASNTAEETISAMKTVRSFANEEEEAEVYLRKLQQVYKLNRKEAAAYMYYVWGSGLTLLVVQVSILYYGGHLVISGQMTSGNLIAFIIYEFVLGDCMESVGSVYSGLMQGVGAAEKVFEFIDRQPTMVHDGSLAPDHLEGRVDFENVTFTYRTRPHTQVLQNVSFSLSPGKVTALVGPSGSGKSSCVNILENFYPLEGGRVLLDGKPISAYDHKYLHRVISLVSQEPVLFARSITDNISYGLPTVPFEMVVEAAQKANAHGFIMELQDGYSTETGEKGAQLSGGQKQRVAMARALVRNPPVLILDEATSALDAESEYLIQQAIHGNLQKHTVLIIAHRLSTVEHAHLIVVLDKGRVVQQGTHQQLLAQGGLYAKLVQRQMLGLQPAADFTAG--------------HNEPVANGSHKA--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A3KGZ4-1", "uniprot_id": "A3KGZ4_DANRE", "id": "A3KGZ4-1", "name": "ABC-type oligopeptide transporter ABCB9", "aln": "MRVAVIVSCNLVFTLVDIVLTTVLYIHGSNIDIFSDETEDFDIHRSTVDLWGTVLIRVSLLFGASIGVFFNRRDGPRRVSNLGTLVALICLTNMTYALAKLLMLSEEGNLMYDPWFLSLFSWTCVAAIGVMIFWKILSQTPNAVSDREDSE--DTERLVDETEDESEKSMKSGKEHTHSGATIGRLLSYCKKDSSLLSIAFFFLLLSAVCEAFIPYYTGQAIDGIVIQKSMDHFAKPMITLSVLALVSSIAIGFRGGVFSVTFARLNIRLRNLLFRSLMHQEIGFFDANHTGDITSRLTSDTTQVSDLISQNVNLFLRSFVKAVGIFIFMFGMSWKLSVVTIMGFPYIAVVSKLYGEYYKKLTKEVQTALAQANKVAEETISAMRTVRSFANEDQEGDMYYSRLQEMFVLNKKQAIAYACFMWSSYISELALQVAILFYGGHLVVTNQMSGGTLISFVIYELELGEALESISSVYTGLMQGVGAAEKVFEYIDRKPKHALNGQEAPETLEGQVEFNNVTFAYPSRPEMDVLKNVSFSLRPGQVTALVGPSGGGKSSCVCLLENFYAPQQGQVLVDGRPVNTYQHKYYHSKVALVAQEPVLFARTVQMNISYGVPEAPMEAVIRAAINANAHDFITGLSKGYDSGVGEKGTQLSGGQKQRVAIARALIRSPRILILDEATSALDSESEYIVQQALNNLMREHTVLVIAHRLSTVERADNILVIDKGSVVEQGPHAELMARGGLYCKLVQRQILGTEIDVDDKNPSPAPTWELKTEDKENAEDCSDTEYETRY", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "**: * .*.* *: :**.:* .. : :: ..*:*. *.:***.: * * .**:**:*** * ****: :::*:** **:.***::** . : **** :** ** :: . :::* :*: . .. * . * : .. .*: ****: :**** * * ::* * ***:::*: *:*:*****:***.********:*:..:: :.:**: **:* *:***:*:: ********** *****: ** .*** *:***: ******** ****:***:*:***. **..*:.:***.:**:**:**:**** * :**::**:***:*:****.***:*...********:********::*.::: :**::: **:*:* ** ::*.* :: *.:**:**:******::.**:.*.**:*:***: **:.:**:.***:**************:***:*. . :* **: ***:*:*:****:* :**. :**:****** **:*********.****** :*****. : *:**:**.*:.:*:*** * ::**:********:: *****:* .*:* *:.** :****.** *..**.: .****:***********:****:*.* :***********:****::***::. ::.****:*********:*. *:*:*** **:**.* :*:*:****.******:** : * . : * :: .::: ", "identical_positions": 410, "similar_positions": 223, "identity": "51.83%" }, { "cls_id": "homologset.agr.MGI:1861731", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "G3V896-1", "uniprot_id": "G3V896_RAT", "id": "G3V896-1", "name": "C-C motif chemokine", "aln": "MQQAGLTLVAVAVCVAFRTSEAILPIASSCCTEVSHHIPRRLLERVNSCSIQRADGDCDLAAVILHVKRRRICVSPHNPTLKRWMSASEMK-NGKENLCPRKKQDSGKDRKGHTPRKHGKHGTRRIHGTHGHEAPR", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9JIL2-1", "uniprot_id": "CCL28_MOUSE", "id": "Q9JIL2-1", "name": "C-C motif chemokine 28", "aln": "MQQAGLTLMAVAVCVAFQTSEAILPMASSCCTEVSHHVSGRLLERVSSCSIQRADGDCDLAAVILHVKRRRICISPHNRTLKQWMRASEVKKNGRENVCSGKKQPSRKDRKGHTTRKH------RTRGTHRHEASR", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9NRJ3-1", "uniprot_id": "CCL28_HUMAN", "id": "Q9NRJ3-1", "name": "C-C motif chemokine 28", "aln": "MQQRGLAIVALAVCAALHASEAILPIASSCCTEVSHHISRRLLERVNMCRIQRADGDCDLAAVILHVKRRRICVSPHNHTVKQWMKVQAAKKNGKGNVCHRKKHHGKRNSNRAHQGKH---------ETYGHKTPY", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*** **:::*:***.*:::******:***********:. ******. * ***********************:**** *:*:** .. * **: *:* **: . :: : ** *: *::. ", "identical_positions": 76, "similar_positions": 28, "identity": "55.88%" }, { "cls_id": "homologset.agr.MGI:1861733", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I6AU25-1", "uniprot_id": "A0A8I6AU25_RAT", "id": "A0A8I6AU25-1", "name": "Pecanex-like protein", "aln": "MGSQVLQILRQGVWASLTGGWFFDPHQSTFSNCFHLYVWIFLLIFPFLLYMVLPPSLMVAGVYCLVVAVIFATIKTVNYRLHAMFDQGEIVEKRNSTMGEQEEEAAQGESSLPRDPGVEMTVFR----KVSSTPPVRCSS-QHSVFGFNQVSELLPRMEDSGPLRDIKELVREQGSNNVIVTSADREMLKLSSQENLIGDLPQTPPG----------------------VVPDPSLPSTDSSERSPMAGDA------VPWGGSSVADTPMSPLLKGSLSQELSKSFLTLTRP--------DRALVRTSSRRE-----------------------------------------QCRGTGG--------------------------------------------------YQPLDRR-------------------------------------GSG---------------DPLPQKAGSSDSCFS---GTDRETLSSFRSEK---TNSTHLDSPPGGHAPEGSDTDPPSEAELPASPDAGVP-------------------------------SDDTLRSFDTVIG----------AGTP--PGQTEPLLVVRPKDLALLRPNKRRPPMRGHS-----------------PPGRTPRR----PLLEGSGFFEDEDTSEGSELSPASSLRSQRRYSTDSSSSTSCYSP-------ESSQGAAGGPRK--------RRAPHGAEEGTAVPPKR---PYGTQRTPSTASAKT----------------------------------------------------HARVLSMDGAG---------------------------------GDVLRAPLAGSKAELEAQPGMELAAGEPAMLPPEARRGPAANQPG---------------------------------WRGELQEEGAVGG--APEETGQRECTSNVRRAQAIRRRHNAGSNPTPPASVMGSPPSSLQEAQRGRAAS-----HSRALTLPSALHFASSLLLTRAGPNVHEASNFDDTSEG-----------------AVHYFYDESGVRRSYTFGLAGGGYENP------------------------------------------VSQPGEQAANGAWDRHSHSSSFHS--------ADVPEATGGLNLLQ--------------------------------------------PRPVVLQGMQVRRVPLEIPEEQ---------------TLMEEAPPRAQHSYKY---WFLPGRWTSVRYERLALLALLDRTRGIMENIFGVGLSSLVAFLGYLLLLKGFFTDIWVFQFCLVIASCQYSLLK-VRPGSPNPQLSWGHNWVIAYSRPVYFCICCLLIWLLDALGT---AQPFPPVSLYGLTLFSASFFFCARDVATVFTLCFPFVFLLGLLPQVNTCLMYLLEQIDMHGFGGTAATSPLTAVFSLTRSLLAAALLYGFCLGAIKTPWPEQHVPVLFSVFCGLLVALSYHLSRQSSDPTVLWSLVRSKLFP------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ELEERSLETARAEP------------------------------------------------------------------------------PDPLPEKMRQSVREVLHSDLVMCVVIAVLTFAISASTVFIALKSVLGFVLYALAGAVGFFTHYLLPQLRKQLPWFCLSQPVLKPLEYSQYEVRGAAQVMWFEKLYAGLQCVEKYLIYPAVVLNALTVEAHTVVNHPDKFCLYCRALLMTVAGLKLLRSAFCCPPQQYLTLAFTVLLFHFDYPRLSQGFLLDYFLMSLLCSKLWDLLYKLRFVLTYIAPWQITWGSAFHAFAQPFAVPHSAMLFLQALLSGLFSTPLNPLLGSAVFIMSYARPLKFWERDYNTKRVDHSNTRLVTQLDRNPGADDNNLNSIFYEHLTRSLQHTLCGDLVLGRWGNYGPGDCFVLASDYLNALVHLIEVGNGLVTFQLRGLEFRGTYCQQREVEAITEGVEEDEGCCCCEPGHLPRVLSFNAAFGQRWLAWEVTASKYVLEGYSISDNNAASMLQVFDLRKILVTYYVKSIIYYVSRSPKLETWLNHEGIAAALRPVRALGYADSDPTFSLSVDEDYDLRLSGLSLPSFCAVHLEWIQYCASRR--------------------------------SQPVDQDWN---------------------------------------------------------------------------------------------------------------------------------------------SPLVTLCFGLCVLGRRALGTASHSMSASLEPFLYGLHALFKGDFRITSPRDEWVFADMDLLHRVVAPGVRMALKLHQDHFTSPDEYEEPAALYDAIAANEERLVISHEGDPAWRSAILSNTPSLLALRHVMDDASDEYKIIMLNRRHLSFRVIKVNRECVRGLWAGQQQELVFLRNRNPERGSIQNAKQALRNMINSSCDQPLGYPIYVSPLTTSLAGSHPQLRALWGGPVSLGAIARWLLRSWERLHKGCGAGCNSGGNVDDSDCAG-----------GGGLTSLSNNPP-----------LAHPTPENTAGSSEQPLPPGPSWGPRP----------SLSGSGDGRPPP----------------------------------LLQWPPPRLPGP--------PPASPAPTEGPRPSRP-----------------------------------------PGPGLLNSEGPSGKWSLGGRKGLG------------------------GPDGEPASGSPK--------------------------------------------------------------------------------------------------------------------------------------------------------GGTPKSQAPLDLSLS--------PDVSSEASPARTTQDIPCLDS--------------------------------------------------------------------------------------------------------SVPESCTPSGAPGDWPVPVEERESPAAQPLLEHQY-----------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8VI59-1", "uniprot_id": "PCX3_MOUSE", "id": "Q8VI59-1", "name": "Pecanex-like protein 3", "aln": "MGSQVLQILRQGVWASLTGGWFFDPHQSTFSNCFHLYVWIFLLIFPFLLYMVLPPSLMVAGVYCLVVAVIFATIKTVNYRLHAMFDQGEIVEKRNSTMGEQEEEAAQGESSLPRDPGVEMTVFR----KVSSTPPVRCSS-QHSVFGFNQVSELLPRMEDSGPLRDIKELVREQGSNNVIVTSADREMLKLSSQEKLIGDLPQTPPG----------------------VVPDPSLPSTDSSERSPMAGDG------VPWGGSGVADTPMSPLLKGSLSQELSKSFLTLTRP--------DRALVRTSSRRE-----------------------------------------QCRGTGG--------------------------------------------------YQPLDRR-------------------------------------GSG---------------DPMPQKAGSSDSCFS---GTDRETLSSFKSEK---TNSTHLDSPPGGHAPEGSDTDPPSEAELPASPDAGVP-------------------------------SDDTLRSFDTVIG----------AGTP--PGQTEPLLVVRPKDLALLRPSKRRPPMRGHS-----------------PPGRTPRR----PLLEGSGFFEDEDTSEGSELSPASSLRSQRRYSTDSSSSTSCYSP-------ESSQGAAGGPRK--------RRAPHGAEEGTAVPPKR---PYGTQRTPSTASAKT----------------------------------------------------HARVLSMDGAG---------------------------------GDVLRAPLAGSKAELEAQPGMELAAGEPAVLPPEARRGPAANQPG---------------------------------WRGELQEEGAVGG--APEETGQRECTSNVRRAQAIRRRHNAGSNPTPPASVMGSPPSSLQEAQRGRAAS-----HSRALTLPSALHFASSLLLTRAGPNVHEASNFDDTSEG-----------------AVHYFYDESGVRRSYTFGLAGGGYENP------------------------------------------VSQPGEQAANGAWDRHSHSSSFHS--------ADVPEATGGLNLLQ--------------------------------------------PRPVVLQGMQVRRVPLEIPEEQ---------------TLMEEAPPRAQHSYKY---WFLPGRWTSVRYERLALLALLDRTRGVMENIFGVGLSSLVAFLGYLLLLKGFFTDIWVFQFCLVIASCQYSLLKSVQPDAASP--MHGHNWVIAYSRPVYFCICCLLIWLLDALGT---AQPFPPVSLYGLTLFSASFFFCARDVATVFTLCFPFVFLLGLLPQVNTCLMYLLEQIDMHGFGGTAATSPLTAVFSLTRSLLAAALLYGFCLGAIKTPWPEQHVPVLFSVFCGLLVAMSYHLSRQSSDPTVLWSLVRSKLFP------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ELEERSLETARVEP------------------------------------------------------------------------------PDPLPEKMRQSVREVLHSDLVMCVVIAVLTFAVSASTVFIALKSVLGFVLYALAGAVGFFTHYLLPQLRKQLPWFCLSQPVLKPLEYSQYEVRGAAQVMWFEKLYAGLQCAEKYLIYPAVVLNALTVDAHTVVSHPDKFCLYCRALLMTVAGLKLLRSAFCCPPQQYLTLAFTVLLFHFDYPRLSQGFLLDYFLMSLLCSKLWDLLYKLRFVLTYIAPWQITWGSAFHAFAQPFAVPHSAMLFLQALLSGLFSTPLNPLLGSAVFIMSYARPLKFWERDYNTKRVDHSNTRLVTQLDRNPGADDNNLNSIFYEHLTRSLQHTLCGDLVLGRWGNYGPGDCFVLASDYLNALVHLIEVGNGLITFQLRGLEFRGTYCQQREVEAITEGVEEDEGCCCCEPGHLPRVLSFNAAFGQRWLAWEVTASKYVLEGYSISDNNAASMLQVFDLRKILVTYYVKSIIYYVSRSPKLETWLNHEGIAAALRPVRALGYADSDPTFSLSVDEDYDLRLSGLSLPSFCAVHLEWIQYCASRR--------------------------------SQPVDQDWN---------------------------------------------------------------------------------------------------------------------------------------------SPLVTLCFGLCVLGRRALGTASHSMSASLEPFLYGLHALFKGDFRITSPRDEWVFADMDLLHRVVAPGVRMALKLHQDHFTSPDEYEEPAALYDAIAANEERLVISHEGDPAWRSAILSNTPSLLALRHVMDDASDEYKIIMLNRRHLSFRVIKVNRECVRGLWAGQQQELVFLRNRNPERGSIQNAKQALRNMINSSCDQPLGYPIYVSPLTTSLAGSHPQLRALWGGPVSLGAIARWLLRSWERLHKGCGAGCNSGGNVDDSDCGG-----------GGGLTSLSNHPP-----------LAHPTPENAAGSSEQPLPPGPSWGPRP----------SLSGSGDGRPPP----------------------------------LLQWPPPRLPGP--------PPASPAPTEGPRPSRP-----------------------------------------SGPALLNSEGPSGKWSLGGRKGLG------------------------GPDGEPASGSPK--------------------------------------------------------------------------------------------------------------------------------------------------------GGTPKSQAPLDLSLS--------PDVSSEASPARTTQDLPCLDS--------------------------------------------------------------------------------------------------------SIPEGCTPSGAPGDWPVPAEERESPAAQPLLEHQY-----------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9H6A9-1", "uniprot_id": "PCX3_HUMAN", "id": "Q9H6A9-1", "name": "Pecanex-like protein 3", "aln": "MGSQVLQILRQGVWASLTGGWFFDPHQSTFSNCFHLYVWIFLLIFPFLLYMVLPPSLMVAGVYCLVVAVIFATIKTVNYRLHAMFDQGEIVEKRSSTMGELEEEPAQGDSNPPRDPGVEMTVFR----KVSSTPPVRCSS-QHSVFGFNQVSELLPRMEDSGPLRDIKELVREQGSNNVIVTSADREMLKLSSQEKLIGDLPQTPPG----------------------AVPDPSLASTDSSEPSPLAGDG------APWSGSSMADTPMSPLLKGSLSQELSKSFLTLTQP--------DRALVRTSSRRE-----------------------------------------QRRGAGG--------------------------------------------------YQPLDRR-------------------------------------GSG---------------EPTPQKAGSSDSCFS---GTDRETLSSFKSEK---TNSTHLDSPPGGPAPEGSDTDPPSEAELPASPDAGVP-------------------------------SDDTLRSFDTVIG----------AGTP--PGLAEPLLVVRPKDLALLRPSKRQPPLRRHS-----------------PPGRAPRR----PLLEGGGFFEDEDTSEGSELSPASSLRSQRRYSTDSSSSTSCYSP-------ESSRGAAGGPRK--------RRAPHGAEEGTAVPPKR---PYGTQRTPSTASAKT----------------------------------------------------HARVLSMDGAG---------------------------------GDVLRPPLAGCKAELEAQVGVEQAASEPVVLPAEARRGPAANQPG---------------------------------WRGELQEEGAVGG--AAEETGRRDRSSSVRRTQAIRRRHNAGSNPTPPASVMGSPPSSLQEAQRGRAAS-----HSRALTLPSALHFASSLLLTRAGANVHEACTFDDTSEG-----------------AVHYFYDESGVRRSYTFGLAGGGYENP------------------------------------------VGQQGEQTANGAWDRHSHSSSFHS--------ADVPEATGGLNLLQ--------------------------------------------PRPVVLQGMQVRRVPLEIPEEQ---------------TLMEEAPPRAQHSYKY---WLLPGRWTSVRYERLALLALLDRTRGVLENIFGVGLSSLVAFLGYLLLLKGFFTDIWVFQFCLVIASCQYSLLKSVQPDAASP--MHGHNWVIAYSRPVYFCICCLLIWLLDALGS---AQPFPPVSLYGLTLFSASFFFCARDVATVFTLCFPFVFLLGLLPQVNTCLMYLLEQIDMHGFGGTAATSPLTAVFSLSRSLLAAALLYGFCLGAIKTPWPEQHVPVLFSVFCGLLVALSYHLSRQSSDPTVLWSLIRSKLFP------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ELEERSLETARAEP------------------------------------------------------------------------------PDPLPDKMRQSVREVLHSDLVMCVVIAVLTFAISASTVFIALKSVLGFVLYALAGAVGFFTHYLLPQLRKQLPWFCLSQPVLKPLEYSQYEVRGAAQVMWFEKLYAGLQCVEKYLIYPAVVLNALTVDAHTVVSHPDKYCFYCRALLMTVAGLKLLRSAFCCPPQQYLTLAFTVLLFHFDYPRLSQGFLLDYFLMSLLCSKLWDLLYKLRFVLTYIAPWQITWGSAFHAFAQPFAVPHSAMLFVQALLSGLFSTPLNPLLGSAVFIMSYARPLKFWERDYNTKRVDHSNTRLVTQLDRNPGADDNNLNSIFYEHLTRSLQHTLCGDLVLGRWGNYGPGDCFVLASDYLNALVHLIEVGNGLVTFQLRGLEFRGTYCQQREVEAITEGVEEDEGCCCCEPGHLPRVLSFNAAFGQRWLAWEVTASKYVLEGYSISDNNAASMLQVFDLRKILITYYVKSIIYYVSRSPKLEVWLSHEGITAALRPVRVPGYADSDPTFSLSVDEDYDLRLSGLSLPSFCAVHLEWIQYCASRR--------------------------------SQPVDQDWN---------------------------------------------------------------------------------------------------------------------------------------------SPLVTLCFGLCVLGRRALGTASHSMSASLEPFLYGLHALFKGDFRITSPRDEWVFADMDLLHRVVAPGVRMALKLHQDHFTSPDEYEEPAALYDAIAANEERLVISHEGDPAWRSAILSNTPSLLALRHVLDDASDEYKIIMLNRRHLSFRVIKVNRECVRGLWAGQQQELVFLRNRNPERGSIQNAKQALRNMINSSCDQPLGYPIYVSPLTTSLAGSHPQLRALWGGPISLGAIAHWLLRTWERLHKGCGAGCNSGGNVDDSDCSG-----------GGGLTSLSNNPP-----------VAHPTPENTAGNGDQPLPPGPGWGPRS----------SLSGSGDGRPPP----------------------------------LLQWPPPRLPGP--------PPASPIPTEGPRTSRP-----------------------------------------PGPGLLSSEGPSGKWSLGGRKGLG------------------------GSDGEPASGSPK--------------------------------------------------------------------------------------------------------------------------------------------------------GGTPKSQAPLDLSLSLSLSL--SPDVSTEASPPRASQDIPCLDS--------------------------------------------------------------------------------------------------------SAPESGTPMGALGDWPAPIEERESPAAQPLLEHQY-----------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P18490-1", "uniprot_id": "PCX_DROME", "id": "P18490-1", "name": "Protein pecanex", "aln": "MGSQTLEILRQGVWASLTGGYFYDPHQGVFCNVVHLYLWLYLLCSPFVAYLYFPSTWLTWCLYCVITSLTILMVKLANLALHRLYDRAQTMSEGN-LKGQFVKVTKETEPRHDDEGGIEMKVIRPGGSRISGEQAINEASEENSIMSIDNVNSIIDLKVDVHRKNSSESIELMFYAPSMLSGGSQQDQQSLAGSASVSKSIRSTGPGGNSSTSAAAQADMFNKYLTVYPEVVEAAGSSAGSADGGSSGGDSRSGAAVSTLGHTGAGTAPAQHVRTGHLSRKCSEVFSRRHRRRLERQSSLDTAAAAANSNAENKLMRNQSDTIATAAPSFLHSQPTNKARGQTNPRQHFITSAPSTGIGGGDAPTSSTAVVVIAPASNSLVNPGRSSRLQRHRSSETHDERLKHQSRGGLFQPILQLPHHSAASSIGALAVLGGGGNVAANDVEDMELGLVRNAGSGGVADACSRALQSWILDPFPDGYLEDDSYTKSDLGIEQPHQPTFRTQHRHHHHHHHLHHHLGGAIIRKDPTSTMSALQLAAVTQPGTGGSVTGGGGAAGGGGSAAGMKRRRHSNATSYKHGSSQSNKSSLVGGGGSRGPSGEAGTSGGAGGTGGVRRIKSAALEVLCPQPSVSNLSPHPNSVEAISGQQQMRNPLPPPSKSLVRNQHLNLYPTQGYGDGTPSAGGGGPGNSSTCSSLFFGSSSACGSTTALIEPPVYPIVEHSDEKTAHEEHGDDCLGIGQGNADDDDEVDDVPIRRRTRALGCSQTHYSVESDVGGFLADEVGADEDVFKDFDDNLEHILSELQQTHNQLDDVLKTHDLHHHSHLHHHKAASVEGAGPSGGSVAVGVSAGNDDEDEETEDNNTGSRSPLLNDRNRQPATLREIQADKQLRQELSHQSGAVIPAPNPPVPIRSEADSGCPSSDCEQVSASSKDQLLSGIELELQQYQILQRCQLDEEQPCTSKMAAKSLGAIPKVVKYREVDELRRRRRGGS-PADAAEAGNEFALVKQTKQASRNSSSSNSTHSISLTDSLTADIHKMLWLMHGGAVDDRGRPITGTSADGTPIPASSSLVPPNMSNAHFQFYQDAIQALQGTHPTSGSSVEHMTNIELARDKLRLDAKLMCEQLVAAAEANSGVRGNTLATQQMTQQQVGMLMRGGSSSRHPSSAPFSVQGLINVIRSERPAARSQLDALQQLSDAAAALAANASEAASVSASGAGGGASSGGGGVLSALGLANHPSNQISQISQLSQMSQPMLNVDGHFAPYCDYWRPACLLSATEKPAAPKSFYKYRFKWCGQEHEFKIAMDRLELLALFDRDLHWMHVLLASLLCTLVACLGAAILQHDHYKDLCALLFCAVIAGAQYSLVKSVQPDAASP--VHGFNKTVAYSRAIYFCLAGGMLLLLKRLDTDYGERTPDPVVFFGMRYSPADVVALLLQALYILLLCFPIIFSVGLCPQINTFLMYLLEQIDMHVFGGNAASSLLGSFLCVVRSVLAVMLLYGPLYGALDEQRGTQYI--LFSIFCAMLVPLGYHLSRCASDFSHLWRLIKTCIVSTYRDDEDEDLSQMQHIATGTVTGSGTANSTALQLTTSTPKQHRQTDVKTEHEQIELSSLEKLTVNEEHHEKDHGADDQLETDQDLPLQQKHSKSKTSSLGSSQQTLGKTISSSKRAITASSSCTSIGTGEPAVEAGALTEEAVEGEEQRRNTLAGEVGSKHELAENYDQAAKIDECEDKISSSSATNPGDMSTLTAGAGTATTDATPACLEADPDAEAEAPADEKQHQGILGTGTGTGTGTTEASENGSGGGANGNTNSNGTGNDLPDPLPRKLQATVTTRLKNDLVVMTLLAVSVLGLHCSTVFTALQPDLNVVLYSFIGVLGLLLHYIVPQMRKHMPWLCFSRPLLRQREFGQFEVLNAPKIMWFEKLYIYLSVLERNVLFPLLAISSLTADSQLIV---AKFGLPWGTLIVAICALKFVRNAYSDPTNQYLIIIFTVLLFRIDFAMATETFIIDYFFVSLAFRKCCDFLLKLQFIVTYIAPWQITWGSAFHAFAQPFSVPHSAMLFLQAAISAVLSTPLNPFLGSAIFLTSYVRPIKFWERDYNTRRIDHSNTRLSSQLERDLGADDNNLNSIFYEHLTRSLQHSLCGDLLMGRWGNVNQGDCFVLASDDLNCLVHIIELGNGLCTFQMRGLEFRGTYCQQREVEAITEDVEDNDGCCCCDPGHLPQLLSANAMFSTRWLAWQVVAAQYVIEGYSISDNLASATLQVFEYRKVLITYYIKSIIYYVVKNPKLEQWLASGPIQDALQHTLSRQFVDLDPIFNFNLDEDFDFRAVGITRSSFCYVYLKWINYCVDMRRDANSMGGAPPAQAPAAAGGASSAPATAGVAPPAPVTPAHNDSKSTPNLSAHGGQAGPSSGQSKSQSQQQLRRPQKSVAQETSVGGGGVVVGGTTVPGTGGVTGGGGDPQLSSSHSFANISRQTSESAPGLGGYVAYMDQNVFVKLAKSSTTTGAGAGAPTSRKESQEKPALRLKLASVGKDAPLVSLCLALGLLARRSLATASHSALTGVEFFLHGLHALFKGDFRITSPRDEWVFADMELLHSVVAPAVKMALKLQQDHITNPDEFLDPHALYDAIDNCSNELVISHEADPVWRSAVLRGAPNLLALRHVMEDGSDEYRIIRLTKRCLSFRVIKLNRECVRGLWAGQQQELIYLRNRNPERGSIQNAKQALRNIINSSCDQPIGYPIYVSPLTTSYADTNAQLCEVIGGAITLDTIRHTVLGWWHRIRERCRQGCSSGSALEPHPGSGPVQLGACNFGSGGSVVGAASTATGVGASTGSGLGVAAPGTAGSTGGESGDLAPVFISAPLYNTLTVNSYYSVRPGNVPGGPIPGNLGGNYVSDSLAVVRGGLAVMPVKPTSTTLIAGLLNRERDETSGSGIMGAGASGPTRATSSGGVRSRRPEVGSSRGRDHERRATLPIASGGAGGEPGKDLTAPQTQVEHEPSPRSTKLSSSSGSLGLGMGVGLGNIITTPGDYPRKTKGPICLTAVDTGTSSSAAEGKPAGSGTVAGTGVGGVIRKPRIEIFKKVIIVDDTGIYDCLDIIDAVVWPTERMRNNGGRLSWKDWEPSAGMVGHVVHCWTPNHKDIRFRSHVNRYVYLVEIGDHYVPVEELGLREYNQIMGSTEEMANSRRSSIQRDFHEYNIQLKLAGLAPIIGGGESSTATTSDASKSHKAKIRAVSSSSSEDEDTSSTRSIPLPQGDDGDLTNFTRLVSMWKEIILDNNKRRLYDMGELSPELLQKLDDAVQQQQQLEDALAEESKEKGTATVTANEGEEGVGEMEIEPEQEQKEVVYLEEQSPLEEVTVSKPDEQPAQPTIPASPVPAETSSTSSAKSTSSPSLCQEEEDAVDPEETPELASEESPSDENGESEAGTTV", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus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identical_positions": 827, "similar_positions": 669, "identity": "24.17%" }, { "cls_id": "homologset.agr.MGI:1861735", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9QYM9-1", "uniprot_id": "TEFF2_MOUSE", "id": "Q9QYM9-1", "name": "Tomoregulin-2", "aln": "--MVLWESPRQCSSWTLCEGFC--WLLLLPVTLLIIARPVKLAAFPTSLSDCQTPTGWNCSGYDDRENDLFLCDTNTCKFDGECLRIGDTVTCVCQFKCNSDYVPVCGSNGESYQNECYLRQAACKQQSEILVVSEGSCAT---DTGSGSGDGV-HEGSGETSQKETSTCDICQFGAECDEDAEDVWCVCNIDCSQTNFNPLCASDGKSYDNACQIKEASCQKQEKIEVMSLGRCQDNTTTTTKSEDGHYARTDYAENANKLEESAREHHIPCPEHYNGFCMHGKCEHSINMQEPSCRCDAGYTGQHCEKKDYSVLYVVPGPVRFQYVLIAAVIGTIQIAVICVVVLCITRKCPRSNRIHRQKQNTGHYSSDNTTRASTRLI", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8I6GGQ4-1", "uniprot_id": "A0A8I6GGQ4_RAT", "id": "A0A8I6GGQ4-1", "name": "Tomoregulin-2", "aln": "--MVLWESPRQCSSWTLCEGFC--WLLLLPVTLLIIARPVKLAAFPTSLSDCQTPTGWNCSGYDDRENDLFLCDTNTCKFDGECLRIGDTVTCVCQFKCNSDYVPVCGSNGESYQNECYLRQAACKQQSEILVVSEGSCAT---DAGSGSGDGV-HEGSGETSQKETSTCDICQFGAECDEDAEDVWCVCNIDCSQTNFNPLCASDGKSYDNACQIKEASCQKQEKIEVMSLGRCQDNTTTTTKSEDGHYARTDYAENANKLEESAREHHIPCPEHYNGFCMHGKCEHSINMQEPSCRCDAGYTGQHCEKKDYSVLYVVPGPVRFQYVLIAAVIGTIQIAVICVVVLCITRKCPRSNRIHRQKQNTGHYSSDNTTRASTRLI", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9UIK5-1", "uniprot_id": "TEFF2_HUMAN", "id": "Q9UIK5-1", "name": "Tomoregulin-2", "aln": "--MVLWESPRQCSSWTLCEGFC--WLLLLPVMLLIVARPVKLAAFPTSLSDCQTPTGWNCSGYDDRENDLFLCDTNTCKFDGECLRIGDTVTCVCQFKCNNDYVPVCGSNGESYQNECYLRQAACKQQSEILVVSEGSCAT---DAGSGSGDGV-HEGSGETSQKETSTCDICQFGAECDEDAEDVWCVCNIDCSQTNFNPLCASDGKSYDNACQIKEASCQKQEKIEVMSLGRCQDNTTTTTKSEDGHYARTDYAENANKLEESAREHHIPCPEHYNGFCMHGKCEHSINMQEPSCRCDAGYTGQHCEKKDYSVLYVVPGPVRFQYVLIAAVIGTIQIAVICVVVLCITRKCPRSNRIHRQKQNTGHYSSDNTTRASTRLI", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "B0S6Y8-1", "uniprot_id": "B0S6Y8_DANRE", "id": "B0S6Y8-1", "name": "", "aln": "MGVSVAAALHEPRSPHQWSRIVGHWVWIAVLSFLATFPVQQLGAFPSSLSDCQTPTGWNCSGDDDRDTDLFLCDTNTCKFDGECLRIGDIITCICNFKCNNDYVPVCGSNNENYENECFLRRDACKQQTEILVVSEGSCPA---DAGSGSGDEAGNEGSAENGQKETSTCDICQFGAECDVDAEDVWCVCNIDCSHISFNPVCASDGRSYDNPCQVKEASCQRQERIEVKFLGHCQGDMITGTKAGDGQYARTDYTEEKPEVSEVARGLYIPCPEHYKNYCVHGDCEYPNMLSTPSCSCHSGFSGPQCDTKEYNVLYVVPGSGKLRYVLIASVIGALQVAIICVVVLCITRKCPRTNRINRQKQNTMHYNSENTLRASTRLI", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8M2BD12-1", "uniprot_id": "A0A8M2BD12_DANRE", "id": "A0A8M2BD12-1", "name": "", "aln": "--MALCAVLRQTRRPPRQENRT-HVVLITTYCFFCISPLKQLCAFPSSLSDCQTPTGWNCSGFEEQDTDLFLCDTNTCKFDGECLRIGDTVTCICDFKCSGDYAPVCGSNGESYENHCLLRKDACKLQTEVLVVSDGACPVGTRDAGSGSGDDA-NEGSAEISQKETSTCDICQFGAECDEDSEDVWCVCNIDCSHISFNPVCASDGRSYDNPCQVKEVSCQKQERIEVKYLGHCK--------------------EEKDQVSEVPWGLYIPCPERYKDYCVHGECEYPSNLSPPTCSCHSGFIGPQCDRKDYNVMYVVPGSGKLRYVLIASIIGALQVAIICLVVLCITRRCPRGNRIARQKQNVPHFNSENTLRASTRLI", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : :: . : : :: :* ***:*************** ::::.********************* :**:*:***..**.******.*.*:*.* **: *** *:*:****:*:*.. *:****** . :***.* .***************** *:************: .***:*****:****.**:**.***:**:*** **:*: *: ::.* . :*****:*:.:*:**.**:. :. *:* *.:*: * :*: *:*.*:*****. :::*****::**::*:*:**:*******:*** *** *****. *:.*:** *******", "identical_positions": 206, "similar_positions": 91, "identity": "53.93%" }, { "cls_id": "homologset.agr.MGI:1861742", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O95166-1", "uniprot_id": "GBRAP_HUMAN", "id": "O95166-1", "name": "Gamma-aminobutyric acid receptor-associated protein", "aln": "MKFVYKEEHPFEKRRSEGEKIRKKYPDRVPVIVEKAPKARIGDLDKKKYLVPSDLTVGQFYFLIRKRIHLRAEDALFFFVNNVIPPTSATMGQLYQEHHEEDFFLYIAYSDESVYG--L---", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P60517-1", "uniprot_id": "GBRAP_RAT", "id": "P60517-1", "name": "Gamma-aminobutyric acid receptor-associated protein", "aln": "MKFVYKEEHPFEKRRSEGEKIRKKYPDRVPVIVEKAPKARIGDLDKKKYLVPSDLTVGQFYFLIRKRIHLRAEDALFFFVNNVIPPTSATMGQLYQEHHEEDFFLYIAYSDESVYG--L---", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9DCD6-1", "uniprot_id": "GBRAP_MOUSE", "id": "Q9DCD6-1", "name": "Gamma-aminobutyric acid receptor-associated protein", "aln": "MKFVYKEEHPFEKRRSEGEKIRKKYPDRVPVIVEKAPKARIGDLDKKKYLVPSDLTVGQFYFLIRKRIHLRAEDALFFFVNNVIPPTSATMGQLYQEHHEEDFFLYIAYSDESVYG--L---", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6PSS4-1", "uniprot_id": "Q6PSS4_DANRE", "id": "Q6PSS4-1", "name": "", "aln": "MKFMYKEEHPFEKRRSEGEKIRKKYPDRVPVIVEKAPKARIGDLDKKKYLVPSDLTVGQFYFLIRKRIHLRAEDALFFFVNNVIPPTSATMGLLYQEHHEEDFFLYIAYSDESVYGDVLKDV", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0AB13A890-1", "uniprot_id": "A0AB13A890_DANRE", "id": "A0AB13A890-1", "name": "", "aln": "MKFQYKEEHPFEKRRSEGEKIRKKYPDRVPVIVEKAPKARIGDLDKKKYLVPSDLTVGQFYFLIRKRIHLRAEDALFFFVNNVIPPTSATMGQLYQEHHEEDFFLYIAYSDESVYGE-----", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9W2S2-1", "uniprot_id": "Q9W2S2_DROME", "id": "Q9W2S2-1", "name": "", "aln": "MKFQYKEEHAFEKRRAEGDKIRRKYPDRVPVIVEKAPKARIGDLDKKKYLVPSDLTVGQFYFLIRKRIHLRPEDALFFFVNNVIPPTSATMGSLYQEHHEEDYFLYIAYSDENVYGMAKIN-", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P38182-1", "uniprot_id": "ATG8_YEAST", "id": "P38182-1", "name": "Autophagy-related protein 8", "aln": "MKSTFKSEYPFEKRKAESERIADRFKNRIPVICEKAEKSDIPEIDKRKYLVPADLTVGQFVYVIRKRIMLPPEKAIFIFVNDTLPPTAALMSAIYQEHKDKDGFLYVTYSGENTFGR-----", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "** :*.*:.****::*.::* :: :*:*** *** *: * ::**:*****:******* ::***** * .*.*:*:***:.:***:* *. :****:::* ***::**.*..:* ", "identical_positions": 62, "similar_positions": 39, "identity": "50.82%" }, { "cls_id": "homologset.agr.MGI:1861746", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A0G2K4B6-1", "uniprot_id": "A0A0G2K4B6_RAT", "id": "A0A0G2K4B6-1", "name": "", "aln": "MKRKIHLISVVMAASKGQERVLLRMWNKGSLVHHWHQSTMICFLLFAILYVLSYFIITRYKRKSDE----QEDEDAVVNRISLFLSTFTLAVSAGAVLLLPFSIISNEILLAFPQNYYIQWLNGSLIHGLWNLASLFSNLCLFVLMPFAFFFLESEGFAGLKKGIRARILETLVMLLLLALLILGIVWVASALIDSDAASMESLYDLWEFYLPYLYSCISLMGCLLLLLCTPVGLSRMFTVMGQLLVKPAILEDLDEQIYMITLEEEALQRR-----LHGLSSSAEYN--------------------------------------VMELEQELENVKTLKTKLERRKKASAWERNLVYPAVMVLLLIETSISVLLVACNILCLLVDETAMPKGTRGPGIGSASLSTFGFVGAALEIILIFYLMVSSVVGFYSLRVFGNFTPKKDDTTMTKIIGNCVSILVLSSALPVMSRTLGITRFDLLGDFGRFNWLGNFYIVLSYNLLFAIVTTLCLIRKFTSAVREELFKALGLHKLHLSDTSRDSETTKPSANGHQKAL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9JIT0-1", "uniprot_id": "LMBR1_MOUSE", "id": "Q9JIT0-1", "name": "Limb region 1 protein", "aln": "--------------MEGQDEVSAREQHFHSQVR----ESTICFLLFAILYIVSYFIIIRYKRKSDE----QEDEDAVVNRISLFLSTFTLAVSAGAVLLLPFSIISNEILLAFPHNYYIQWLNGSLIHGLWNLASLFSNLCLFVLMPFAFFFLESEGFAGLKKGIRARILETLVMLLLLALLILGMVWVASALIDSDAASMESLYDLWEFYLPYLYSCISLMGCLLLLLCTPVGLSRMFTVMGQLLVKPAILEDLDEQIYMITLEEEALQRR-----LHGLSSSVEYN--------------------------------------VMELEQELENVKILKTKLERRKKASAWERNLVYPAVMVLLLIETSISVLLVACNILCLLVDETAMPKGTRGPGIGSASLSTFGFVGAALEIILIFYLMVSSVVGFYSLRFFGNFTPKKDDTTMTKIIGNCVSILVLSSALPVMSRTLGITRFDLLGDFGRFNWLGNFYIVLSYNLLFAIMTTLCLIRKFTSAVREELFKALGLHKLHLSDTSRDSETTKPSANGHQKAL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8WVP7-1", "uniprot_id": "LMBR1_HUMAN", "id": "Q8WVP7-1", "name": "Limb region 1 protein homolog", "aln": "--------------MEGQDEVSAREQHFHSQVR----ESTICFLLFAILYVVSYFIITRYKRKSDE----QEDEDAIVNRISLFLSTFTLAVSAGAVLLLPFSIISNEILLSFPQNYYIQWLNGSLIHGLWNLASLFSNLCLFVLMPFAFFFLESEGFAGLKKGIRARILETLVMLLLLALLILGIVWVASALIDNDAASMESLYDLWEFYLPYLYSCISLMGCLLLLLCTPVGLSRMFTVMGQLLVKPTILEDLDEQIYIITLEEEALQRR-----LNGLSSSVEYN--------------------------------------IMELEQELENVKTLKTKLERRKKASAWERNLVYPAVMVLLLIETSISVLLVACNILCLLVDETAMPKGTRGPGIGNASLSTFGFVGAALEIILIFYLMVSSVVGFYSLRFFGNFTPKKDDTTMTKIIGNCVSILVLSSALPVMSRTLGITRFDLLGDFGRFNWLGNFYIVLSYNLLFAIVTTLCLVRKFTSAVREELFKALGLHKLHLPNTSRDSETAKPSVNGHQKAL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M2BDY2-1", "uniprot_id": "A0A8M2BDY2_DANRE", "id": "A0A8M2BDY2-1", "name": "", "aln": "----------------MEDDVTIREQNFHSQVR----EYIVCFLLFAVLYIVSYCIISQYKRKSDD----QEDEDAIVNRISMYLCTFTLAVSGGAVLLLPFSIISNEILLSLPKNYYIQWLNGSLIHGLWNLVSLFSNLSLFVLMPFAYFFLESEGFAGSKKGIKARVLETFVMLFLLGLLILGIVWVASALIDNDAASMESLYDLWEFYLPYLYSCISLMGGLLLLMCTPVGLSRMFTVMGQLLVKPTILEDLDEQIYCIQLQEEALERR-----LNGTTSNSYLHG-----------------------------------NSQHHLHKELDSVRNQRHKLERRKKASAWEKNLLYPIVMLILLAGTTISVLLVALNIVYLLVDETAMPKGSTERDIGNASLSTFGVAQAVVEIILMFYLLVSSVVGFYSLRIFQELTPRKDDTNMTTIIGCCVSILVLSSALPVMSRTLGITRFDLLGDFGRFNWLGNFYIVLSYNLLFAVVTTLCLVRKFTSAVREELLKALGLDKLNLSTSTTDAESGKHVVNGHQKTL", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VC35-1", "uniprot_id": "LILI_DROME", "id": "Q9VC35-1", "name": "Protein Lilipod", "aln": "-----------MDEEEEEEVTDLKLQLFHNTVR----EHIIFLLLIILLYSSSYVVVSRFRRRDRDDLYSNDEDEVLVYRISFWLCTFTLAVAEGAAMLLPVSIASNEVLLLYPNSYYVKWLNSSLIQGLWNHVFLFSNLSLFIFLPFVYLFSESTGFVGNKKGILPRVYETFTVFMLMAIIVLVLTAVLSAVFGIEKLQFFWFLNLGSVHLPFLYSCVSFLGVMLMLICTPYGFVRLFGVVNQVLVRPMLLRDVNEEFSAFYMEEASVKRKLAHIELHNVSIADAANGGRLGNRIGLGRGRTFYPQPLLQHSQAHLYQRKAMASDVDELNDRLRELDSERKELDKLRTSSTFQRTFVYPLAMLLLLFCTAVTILLVVQNTLELLIGIKALPLSTRQFALGISSLSKLGPFGAGLEVCLIFYLGATSVVGFYSMPFMRKVCPKRRQTSLPQLMLNCGFMLVLSSALPLLSRIIGITNFDLLGDFGAIEWLGNFQIVLLYNLVFGTTTALCLANKFTATVRRELRARLVENYVLFTNYIS-------FIN------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :: . : . *: . : :**: :** ** :: :::*:. : :::::.:* ***::*.******: **.:***.** ***:** *:.**::***.***:**** . *****.**:::**.::* ** **.* **** .*: **:.:::*:.:::* :. * **::. : .: : :* ..:**:****:*::* :*:*:*** *: *:* *:.*:**:* :*.*::*:: : ::* :::*: *:. : : .*...* .: : :*:: :.:*::::.::** .*::** *::::***. * : **:. .*:* .: :* :***.:* * :*: *:*** .:*******: .: :. *:: :*.:. :: * :********::** :***.******** ::***** *** ***:*. *:*** .***::**.** * . : :. * ", "identical_positions": 184, "similar_positions": 179, "identity": "33.15%" }, { "cls_id": "homologset.agr.MGI:1861747", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "F7ENQ2-1", "uniprot_id": "F7ENQ2_RAT", "id": "F7ENQ2-1", "name": "RING finger protein 32", "aln": "MLKNKDRSSKKSNLAVSAVALQDHILRDLQLGHLSVADPCKTKVQKKENKSQSLRKGSAAMMDTGLRKTAEGPKGEDPEKEYVLDPTPPPLTLAQKLGLLALPPLPLSSDEWEKVKQRSLLQGDSMQPCPICKEEFELQPQVLLSCSHVFHRACLQAFEKFTNRKTCPLCRKNQYQTRVIHDGARLFRVKCATRIQAYWRGYIVRKWYRNLRKMIPPTDAKLRRKFFEEKFTEISHRILCSYNTNIDELFSEIDVCLAVNRSILQQLDERCGQEITEEDWEKIQAQAAHHEIYECSICLTPLFFHCDGRQAAAGTSSQHPRETVLLSCAHLFHNACLLALEEFSLGDNAPFNVCPLCRSCYQKKIVEY", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9JIT1-1", "uniprot_id": "RNF32_MOUSE", "id": "Q9JIT1-1", "name": "RING finger protein 32", "aln": "MLRNKDRSSNKGNLAVTAVALQDHLLHDLQLGHLSVADPCKIKARKKEKKSKSLKRDATAIIDTGLRKSTEGPNMEDPEKEYVLDPTPPPLTLAQKLGLLPPPPLPLSSDEWERVKQRSLLQGDSIQPCPICKEEFELHPQVLLSCSHVFHRACLQAFEKFTNKKTCPLCRKNQYQTRVIHDGARLFRVKCATRIQAYWRGYIVRKWYRNLRKIIPPSDAKLRRKFFEEKFTEISHRILCSYNTNIDELFSEIDVCLAVNRSILQQLDERCGQIITKEDWEKIQAQAAHHEIYECSICLTPLSFHGDGRQAAIGTSSQRPRETVLLSCAHLFHNACLLALEEFSLGDNAPFHVCPLCRSCYQKKIVEC", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9H0A6-1", "uniprot_id": "RNF32_HUMAN", "id": "Q9H0A6-1", "name": "RING finger protein 32", "aln": "MLKNKGHSSKKDNLAVNAVALQDHILHDLQLRNLSVADHSKTQVQKKENKS--LKRDTKAIIDTGLKKTTQCPKLEDSEKEYVLDPKPPPLTLAQKLGLIGPPPPPLSSDEWEKVKQRSLLQGDSVQPCPICKEEFELRPQVLLSCSHVFHKACLQAFEKFTNKKTCPLCRKNQYQTRVIHDGARLFRIKCVTRIQAYWRGCVVRKWYRNLRKTVPPTDAKLRKKFFEKKFTEISHRILCSYNTNIEELFAEIDQCLAINRSVLQQLEEKCGHEITEEEWEKIQVQALRRETHECSICLAPLSAAG-GQRVGAGRRS---REMALLSCSHVFHHACLLALEEFSVGDRPPFHACPLCRSCYQKKILEC", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "**:**.:**:*.****.*******:*:**** :***** .* :.:***:** *::.: *::****:*::: *: **.********.************: ** ********:***********:************:************:***********:************************:**.********* :********** :**:*****:****:*****************:***:*** ***:***:****:*:**: **:*:*****.** ::* :******:** *::.. * * ** .****:*:**:**********:**..**:.************:* ", "identical_positions": 270, "similar_positions": 68, "identity": "73.37%" }, { "cls_id": "homologset.agr.MGI:1861749", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q3UFM5-1", "uniprot_id": "NOM1_MOUSE", "id": "Q3UFM5-1", "name": "Nucleolar MIF4G domain-containing protein 1", "aln": "MPRNVPEVNGVYRHGACELWCRAMAHALLKRSGVRRG-LGGREGPLKRLRLAVEDFVRTTSESEA---CESRSAVARSRPGGRKSRKELRKEKRHLRKARRLQRTVGSGSGDQGGNVGLNDGPETRRPPTEVRPTPAKATATPAKASAP---STNTKASAAQPKA--------------KAKGAPGKPGPATATARKRALLAANEEEDREIRKLERCLGLHKRKKKGDGSSVPLSFARDGLDYILGALECGSGG-GLYESSEEEEEEKLETGQTVLE---SDLE---SNSK-ESEEDPDWQVLQE------------DQEDVNSKRRGEAESGTRGNKGTKKVRFAEVVEKSRSSSEDDIEQQ--ESHSVESGEKYIPPRLR-NEEVIDV---HKKEELDRLKKHVKGLINRLSEPNMASISGQLEELYMAHSRKDMNDTLTTALMDACVTASAMPSRLMMEHVFLVSILHHTVGIEVGACFLEAVVKKFDAIYRD-----------GGEGKELDNLFTMIAHLYNFHVVQSILIFDILKKLVGTFTEKDIELILLMLKNVGFALRKDDALSLKELITEAQTQASGAGNKFQDQNRVRFMLETMLALKNNDLRKIPGYNPEPVEKLKKLQRTLVRNAGSGSETRLRISWDGILNAEQTGRWWIVGSAWSG-----TPMIDNSHHIQLQKPLAG-MASSKMLE-------LARKQRMNTDVRRIIFCTLMTSEDFLDAFEKLLKLGLKDQQEREIVHILMDCCLQE---KTYNPFYAFLASKFCDYERRFQMTFQFSIWDKFRDLENLPDT------------------KFSNLVHLLAHLLRTKSLPLSVLKVVEFS-ELDKPRVHFLRRVLTALLMETEDDD--------------------LAVIFSRVSDNPKLGMLREGLKLFIG-----HFLLKHTQAHQS---AEEASLLREKAGLASKSLQG-KAILRM", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8I6AUC8-1", "uniprot_id": "A0A8I6AUC8_RAT", "id": "A0A8I6AUC8-1", "name": "Nucleolar MIF4G domain-containing protein 1", "aln": "-------------------------MARTKCSGVRRG-PGGGKGPLKRLRLAVEGFVRATSESEA---CENRSAVARSRPGDRKSRKELRKKKRQLRKVRRLQRTVGSGSGDQEGNVGLNGGPETR-PRIEMRPTPAKATATPVKASAP---SANTKASATQPKANSSYSKGTMTSTQAKAKGAPGKPGPATATARKRALLAANEEEDREIRKLERCLGLHKRKK-GDGSSVPLSFARDGLDYILGALEYGRSG-GLYESSDEEEEGKVETGQTFLE---SDPE---SNSE-ESEEDPDSQVPQE------------DQEDVNSQKEGETESGTRGNKGNKKVRFAEVVEKSESSLEDDLEHQ--ESHCVESGEKYIPPQLR-SEETVDV---QKKEELDRLKKHVKGLINRLSEPNMASISGQLEELYMAHSRKYMNDTLTAVLMDACVTTSTMPSRLMMEHVFLVSILHHTVGTEVGACFLEAVVKKFDDVYRD-----------GGEGKELDNLFTMIAHLYNFHVVQSLLIFDILKKLVGTFTERDIELILLMLKNVGFALRKDDALSLKELITEAQAQAIGAGNKFQDQNRVRFMLETMLALKNNDMRKIPGYNPEPVEKLKKLQRALVRNASSGSETQLRISWDGILNAEQTGRWWIVGSAWSG-----TPMIEN-HHTHLQKPLAG-TASSKMLE-------LARKQRMNTDVRRNIFCTMMTSEDFLDAFEKLLKLGLKDQQEREIVHILMDCCLQE---KTYNPFYAFLASKFCAYERRFQMTFQFSIWDKFRDLENLSGT------------------KFSNLVYLLTHLLKTKSLPLSVLKVVEFS-ELDKPRVHFLRRVLTELLMETEDDD--------------------LVVIFSRVSSNPKLGMLREGLKLFIS-----HFLLKPAQPQQS---AEKASLLRERAGLASKSLQG-KAILRM", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q5C9Z4-1", "uniprot_id": "NOM1_HUMAN", "id": "Q5C9Z4-1", "name": "Nucleolar MIF4G domain-containing protein 1", "aln": "----MAASRSAGEAGPGGSQGRVVRMKRRGGRGPRRGPAGGGEKALKRLKLAVEEFVHATSEGEAPGGCEGRGAPVSFRPGGRKSRKELRKEKRHLRKARRLQRTAGPEQGP-----GLGGRSGAEEASGHRQDTEERARPAPSRDPSP---PRKPRPSRVKAKAT-------------AATAKTRPSAAATAAARKRALLAANEEEDREIRKLERCLGLNKRKKKDGSSSVPLSFARDGLDYILGALESGKNS-GLYDSSGEEEE---DAGQTLPE---SDLE---SDSQDESEEEEEGDVEKEKKAQEAEAQSEDDDEDTEEEQGEEKEKGAQEKRRGKRVRFAEDEEKSENSSEDGDITD--KSLCG-SGEKYIPPHVRQAEETVDF---KKKEELERLKKHVKGLLNRLSEPNMASISGQLEELYMAHSRKDMNDTLTSALMGACVTASAMPSRLMMEHVLLVSILHHTVGIEVGAHFLEAVVRKFDAIYKY-----------GSEGKECDNLFTVIAHLYNFHVVQSLLIFDILKKLIGTFTEKDIELILLMLKNVGFSLRKDDALSLKELITEAQTKASGAGSEFQDQTRIRFMLETMLALKNNDMRKIPGYDPEPVEKLRKLQRALVRNAGSGSETQLRVSWDSVLSAEQTGRWWIVGSAWSG-----APMIDNSHHTHLQKQLVG-TVSSKILE-------LARKQRMNTDIRRNIFCTIMTSEDFLDAFEKLLKLGLKDQQEREIIHVLMDCCLQE---KTYNPFYAFLASKFCEYERRFQMTFQFSIWDKFRDLENLPAT------------------NFSNLVHLVAHLLKTKSLSLSILKVVEFS-ELDKPRVRFLRKVLSILLMETEVED--------------------LSLIFTRVSDNPKLGVLREGLKLFIS-----HFLLKNAQAHRS---ADEANVLREKADLATKCLQG-KASLRM", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q1LY17-1", "uniprot_id": "Q1LY17_DANRE", "id": "Q1LY17-1", "name": "Nucleolar MIF4G domain-containing protein 1", "aln": "------------------------MKAKRQRKG--KGGKQANNDKFKKLKDSVSDFVKSKGGFDK---NENDQRVNFVK---RKSRKDLRKEKRKMKKAKMKSHYMGQAMAKS--SEELNPNTPAVKEENTHKPVLKKTTDAPQRQQKTKKGDAKTKDAKDETKSKK---------VHFSEDLPKQKKKSGLNESRKLALLEANVEEDREIKKLEKRLGLNKRKN---KKSLPQSFTNDGLDYILGILEPGASATGLYESDEEMDIDKAKENFDELE---EDSEEQMTDDEDTGDGEEEDEAQME------------EEEDVEEEDTQIDDEEVEGDEEDDTDASEENEEVEEAESEQKNPES--QELNPATTGKYVPPHLR---EAADS---KRKAELEKLKRSVKGLINRLSQPNMASISSQLEELYMNTSRKDMNDTLTDILLAACVTPALMPERLLMEHILLVSVLHYSVGLEVGAHFLETVVRQFDRIYSEL----------DGTDKECDNLVSIIAHLYNFHVVHAVLVFDILKKLVTSFSSKDIELLLLVLKTVGFALRKDDPIALKELISEAQRKASAEGEQFQDQTRIRFMLETMMALKNNDMRKIPGYDPEPVEKLRKLQRTLIHSSAGSSDMKLRVSLDNLLEAERVGRWWIVGSSWSG-----APMIDDQGNKTTTPSTKGEQYSAKMLE-------LARKQRMNTDVRRNIFCVLMSSEDFLDAYEKLLRLGLKDQQEREIVHVLMDCCLQE---KMFNRFYAVLAEKLCSHDRRFQMTFQFSLWDKFRDLANLSNR------------------SFSNLVQLVTHLLHRKSLSLSILKAIEFG-ELDKPKVKFLKQILSKLLKETEPED--------------------LVNIFGRISGIPKLGMLREGLKLFIS-----HFLLRTVNTQEP---PEQAKVLKDRAEVATKAMEARDAKIKL", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9W020-1", "uniprot_id": "NOM1_DROME", "id": "Q9W020-1", "name": "Nucleolar MIF4G domain-containing protein 1 homolog", "aln": "-----------------------MAKIKKKEAKAKPLTRKEQRKQKSEFKKQNKRLYFAGKTNGTQRVAAAAEALAAQSQLGKNKKKKRSKKPKIINPDEIPKEQLLSGEIDSDDDESIDSDFSDAEVDALLPAREKMEVYEPLGKKVKKTTGGAIQRQDEEAVRR-------------KELRQQKELESKSKKQRIKQLRIENEEDDREINKLEKKLKLNKSKD---KNRLVRKMFNDGLDYLLDFVLDDEEEKRKWEEKQERKKKLKEQQEKEEAGMWSDEEEDKEDRDEPMDNFSEDDSGSE------------GEDDDEDLTGEEEQSEEDSEQEENAPKIKEDIYGRKRDAEGNILPDPVELEASAAGQKYIPPHQRALMAASAGSSEKQAEILARLLKQCKGLLNRLSEANLHKIAAGIEELYMKNSRYNMNETLTKLIQEALLGYTRTNERMVQEHMVLLAYLHAQVGSEIGAHFLQTFVELFDGYVKNIAT-------LEVEDKQLNNLVLVLCYMYLFKIYELNLLMELIGKLSDQLCEKSVECLLLIFQSIGFRLRKDDPLAFKTMMQKVQSQIASAPLELKENPRLRFMVDILNAVKNNNMQKLPQYDPELAENLRKRLKAMLKNDR--YVVTLNITLEDLLRADKVGKWWIVGSAWTGNLD-EMGSAKQKQDKNSSKSANG-GFADQLLE-------LARKQQMNTAERRNIFCIIMSAADYVDAFEKILHLSLKDQ--RAVAYVIIHCALNE---KRANPYYAHLALKFCQFNRKYQLAFQFASWDRINDIEKLSKP------------------QIRNLASFLQQVILAAGLQLSVLKVVDFM-QLDKLSFYFMKEVMVRLLLANDERE--------------------IYQTFERVAKNTKLQQFKQSVRLFLQ-----HFLLQEEQLDKLKLKDEDRQLLQQRVDHIDKLLAYVDL----", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q06132-1", "uniprot_id": "SGD1_YEAST", "id": "Q06132-1", "name": "Suppressor of glycerol defect protein 1", "aln": "-----------------------------MQKTDGIRIPGVILDELKTLDYSQDERFSISEGKKRRRGNGKHLSRKEKRKMERADKKRKIISTREINSSRLKSAPTSEKRSANAGVKNVGKQANGKNPISSDESESNENWDSDEVLTDEVAEESGEQAMSAEETMK--------------KLESLKRKAKGIQGAENSGEIKGNSYEKKHIRNRDTNENFVSYPL---APSDRSAFERDEMDMQYYAKKLGLKG----ERKAIHAKDEFDAIGGLLEG-LEYFENYGKSDEEYGDFATETNSMRK------------DDEASEKAFSSDDDLSASDFEDSDGLSESDNDSVADSDDNYRREKENPYVAPTQSVESYVPPSLRKKLDDSEN-----NSTLSEISKKVNSSLNKLSDSNITIIITDLNRLYDSLPRQYVTESLTKGILNIISQNQKLLDGFIMNYAALAYTLSKLRGIEVGAFFIQKTVEAFLHHYEEEMENILKDQQSKISSKICINIATLLSYCYNFGFVSCRLIYDIIRIFVADPNEFTTELLLRIISISGQLIRGDDPSALRDIRSELLKNAKNLK---EQSPRLRFLMDTMSDLKNN--RLKPSILATDHHPLKKNLQSILNSSS--SWEPLQVSLEDIKNIDSKGKWWLVGASWRGNMENAFEVSINNENDASKSKKSKISIEDDLLDDIPDWNIIARQQRMNTDIRRAIFISIMSAQDYLDAFSKLEKLSLKNKQVLEIPRIVLHCLLADSGSNGYNHYYALVANKICERYSHLSKSFQFLFWDVIKKFEDKEFDSESDTDEEDDLDDKEKLLRISNQGRFFGSLLANDILKLDVFKHVPFMGGLNTEGMLFMEILLFQLFLTVAKKSEKKLKMDESGNKRIIYSDDYLRDVLTKNVKSENMLFILKGLKWFINKKFRYHNFLAGKKGDKAFDRDERRLAWASKAAKSIIDKELENIDS--", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . : . : .:* . : :. . . :. : : . * :.:.*.: : : . : .* :* . : . . . * . . : : : : :: :. : . . : . : . : .*:** * * .: : :. :*:**:.*: * ::.** .* :.::** : . :: :: * * * *:** *:: *. * .* *: ::.: * * . *: ::: : . * :* ::. * :* **. ::: : : : ::. *:**::: : :*** : * . . *:* ::::.. *.:: :.: : *:**:**::* * : . .:*: :**:*:*** ** ** :*:: *::**:.*: :*.**:: : :::.* * : : * :** :* *:* : . :*** ** :..: . : * :. :: * *.::* : * *:. . *:. :: *: . : : : :: : :.:: *: * :* : .. : .:. . ", "identical_positions": 101, "similar_positions": 213, "identity": "10.35%" }, { "cls_id": "homologset.agr.MGI:1861755", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9EPI6-1", "uniprot_id": "NSMF_RAT", "id": "Q9EPI6-1", "name": "NMDA receptor synaptonuclear signaling and neuronal migration factor", "aln": "MGAAASRRRALRSEAMSSVAAKVRAARAFGEYLSQSHPENRNGADHLLADAYSGHE-GSPEMQPAPHNKRRLSLVSN-------------G---------------RYEGSISDEAVSGKTATEG--PQPRVYTISREPALLP--GSEAEAIELAVVKG-------------RRQRER-------------HPHHHSQPLRASP-----------------GSSRE---------DISRPCQS---------WAGSR-----QGSKECPGCAKLVPGPSPRAFGLEQPPLPEASGRHKKLERMYSVDGVS---DDVPIRTWFPKENPFSFQTATTTMQAISVFRGYAERKRRKRENDSASVIQRNFRKHLRMVGSRRVKAQTFAERRERSFSRSWSDPTPMKADTSHDSRDSSDLQSSHCTLDEA-CEDLDWDTEKGLEATACDTEGFLPPKVMLISSKVPKAEYIPTIIRRDDPSIIPILYDHEHATFEDILEEIEKKLNIYHKGAKIWKMLIFCQGGPGHLYLLKNKVATFAKVEKEEDMIHFWKRLSRLMSKVNPEPNVIHIMGCYILGNPNGEKLFQNLRTLMTPYKVTFESPLELSAQGKQMIETYFDFRLYRLWKSRQHSKLLDFDDVL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q99NF2-1", "uniprot_id": "NSMF_MOUSE", "id": "Q99NF2-1", "name": "NMDA receptor synaptonuclear signaling and neuronal migration factor", "aln": "MGAAASRRRALRSEAMSSVAAKVRAARAFGEYLSQSHPENRNGADHLLADAYSGHD-GSPEMQPAPQNKRRLSLVSN-------------G---------------RYEGSISDEAVSGKPAIEG--PQPHVYTISREPALLP--GSEAEAIELAVVKG-------------RRQRER-------------HPHHHSQPLRASP-----------------GSSRE---------DISRPCQS---------WAGSR-----QGSKECPGCAQLVPGPSSRAFGLEQPPLPEAPGRHKKLERMYSVDGVS---DDVPIRTWFPKENLFSFQTATTTMQAISVFRGYAERKRRKRENDSASVIQRNFRKHLRMVGSRRVKAQTFAERRERSFSRSWSDPTPMKADTSHDSRDSSDLQSSHCTLDEA-CEDLDWDTEKGLEAMACNTEGFLPPKVMLISSKVPKAEYIPTIIRRDDPSIIPILYDHEHATFEDILEEIEKKLNIYHKGAKIWKMLIFCQGGPGHLYLLKNKVATFAKVEKEEDMIHFWKRLSRLMSKVNPEPNVIHIMGCYILGNPNGEKLFQNLRTLMTPYKVTFESPLELSAQGKQMIETYFDFRLYRLWKSRQHSKLLDFDDVL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6X4W1-1", "uniprot_id": "NSMF_HUMAN", "id": "Q6X4W1-1", "name": "NMDA receptor synaptonuclear signaling and neuronal migration factor", "aln": "MGAAASRRRALRSEAMSSVAAKVRAARAFGEYLSQSHPENRNGADHLLADAYSGHD-GSPEMQPAPQNKRRLSLVSN-------------G---------------CYEGSLSEEPSIRKPAGEG--PQPRVYTISGEPALLP--SPEAEAIELAVVKG-------------RRQR---------------HPHHHSQPLRASP-----------------GGSRE---------DVSRPCQS---------WAGSR-----QGSKECPGCAQLAPGPTPRAFGLDQPPLPETSGRRKKLERMYSVDRVS---DDIPIRTWFPKENLFSFQTATTTMQAISVFRGYAERKRRKRENDSASVIQRNFRKHLRMVGSRRVKAQTFAERRERSFSRSWSDPTPMKADTSHDSRDSSDLQSSHCTLDEA-FEDLDWDTEKGLEAVACDTEGFVPPKVMLISSKVPKAEYIPTIIRRDDPSIIPILYDHEHATFEDILEEIERKLNVYHKGAKIWKMLIFCQGGPGHLYLLKNKVATFAKVEKEEDMIHFWKRLSRLMSKVNPEPNVIHIMGCYILGNPNGEKLFQNLRTLMTPYRVTFESPLELSAQGKQMIETYFDFRLYRLWKSRQHSKLLDFDDVL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "B8PYG1-1", "uniprot_id": "NSMF_DANRE", "id": "B8PYG1-1", "name": "NMDA receptor synaptonuclear signaling and neuronal migration factor", "aln": "MGTVVSKKENLRNDAISSVAAKVRAARAFGEYLSHTRPENRNRSDHLLSDTFIGQETDSPDISRLNNNNSLQPYSQHTLIVKPSQEELQQGSQSAPLP-TSSKRRLSVERSLSSEDQQNQRRTESSVKPARVYTITRERDMLG-GQGSEESLELEVLKR----------TSEPSQINPPTGLRG--------SHHRGSQHRGNN-----------------GPTHQHHYG---HAPMAQPLQSSGSTHNIRDWGSRRSRSREDCTPDCVACIR-PHCQSQRSLDLDTSPHGGGKQHKK-LERMYSEDRVSSEDREDHTNSWFPKENMFSFQTATTTMQAISNFR-KHLRMVGSRR----------------------VKAQTFVDRKAKSFSRSWSDPTPVKPDSLHDSRDSGDLQASSGNLDEEDCDDVDWEEERELERVACEGDDFIPPKLMLISSKVPKAEYVPNIIRRDDPSIIPILYDHEHATFDDILEEIEKKLTAYRKGCKIWNMLIFCQGGPGHLYLLKNKVATFAKVEKEEGMMQFWKKLGRFMSLLNPEPNLIHIMGCYVLGNANGEKLFQNLKRLMKPHGIEFKSPLELSAQGKEMIEMYFDFRLYRLWKTRQHSKLHDYDDLL", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0AB32TGV5-1", "uniprot_id": "A0AB32TGV5_DANRE", "id": "A0AB32TGV5-1", "name": "", "aln": "MGTAVSKRKNLRNDAISSVAAKVRAARAFGEYL-HTHPENCNGSDHLLSDTLVGHDSDSPDSLCAQNNNHSCTLQGSPISTDASLINPALGLLEPPPPTTSSKSRLSLERSFSAEEDQ-QKCVECALQPARVYTITGESGMLGTSRGSKENLELEVLKEALSQPSTSSNTSSPTQRHHHHGGGGGGGNHHHSNHHHSNHHHANTSGSSGNSGSTPQNISGAGTSHHHHVVSHHHHHLSQPLQSSVSAHNLRGWGEGK-----ECGLACESCPG-APSRSQGSLDLESSTREAGKQRRPPLERMCSVDRVTGLERDD--NSWFPKENMFSFQTATTTMQAISVFRSLAERQRRKSE----------------------VESAAIIQRNFRKHLR--------MVGSRRMKAQSGELQGTCCTPDEARCEDMDWEEEREMERLACEGDDFIPPKIMLISSKVPKAEYLPNIIKRDDPSIIPILYDHEHATFDDILEEIEKRLTAYRRGSKIWRMLIFCQGGPGHLYLLKNKVATFAKVEKEEDMSQFWKRLSRFMSKLNPEPNLIHIMGCYVLGNPNGEKLFQKLKNLMRPYSVTFESPLELSAQGKEMIEMYFDFRLFRLWKTRQHSKLLDYEDLL", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "**:..*::. **.:*:***************** :::*** * :****:*: *:: .**: :*: . * * *:* * : * .:****: * :* . * :** *:* * **:.. :.. * ::. :::* ** *. : : * .* : ::.*: .. :: **** * * *: : .:****** ************** ** * . . *:: :: :*. :.. * .: : . :*.:**.: . ** :*:**: *: :* **: :.*:***:************:*.**:******************:*******::*. *::*.***.*****************************.* :***:*.*:** :*****:*******:***.*******:*: ** *: : *:**********:*** ******:****:****** *::*:*", "identical_positions": 255, "similar_positions": 122, "identity": "40.16%" }, { "cls_id": "homologset.agr.MGI:1861774", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q5PQP1-1", "uniprot_id": "RBMS1_RAT", "id": "Q5PQP1-1", "name": "RNA-binding motif, single-stranded-interacting protein 1", "aln": "------------------------------------------------------------------------------------------------------------------------------------MGKVWKQQMYPQYATYYYPQYLQAKQSLVPAHP----------------------MAPPSPSTTSSNNNSSSSS---------------------------NSGWDQLSKTNLYIRGLPPNTTDQDLVKLCQPYGKIVSTKAILDKATNKCKGYGFVDFDSPAAAQKAVSALKASGVQAQMAKQQEQDPTNLYISNLPLSMDEQELENMLKPFGQVISTRVLRDSSGTSRGVGFARMESTEKCEAVIGHFNGKFIKTPPGVSAPTEPLLCKFADGGQKKRQNPNKYIPNGRPWPREGE---AGMTLTYDPTTAALHNGFYP-SPYSIATNRMITQTSLTPYIASPVSAYQVQSPSWMQPQPYILQHPGAVLTPSMEHTMSLQPASMISPLAQQMSHLSLGST----GTYMP--ATSAMQGAYLP---QYTHMQTATVPVEEASGQQQVTVETSNDHSPYTFPPNK---", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q91W59-1", "uniprot_id": "RBMS1_MOUSE", "id": "Q91W59-1", "name": "RNA-binding motif, single-stranded-interacting protein 1", "aln": "------------------------------------------------------------------------------------------------------------------------------------MGKVWKQQMYPQYATYYYPQYLQAKQSLVPAHP----------------------MAPPSPSTTSSNNNSSSSS---------------------------NSGWDQLSKTNLYIRGLPPNTTDQDLVKLCQPYGKIVSTKAILDKATNKCKGYGFVDFDSPAAAQKAVSALKANGVQAQMAKQQEQDPTNLYISNLPLSMDEQELENMLKPFGQVISTRVLRDSSGASRGVGFARMESTEKCEAVIGHFNGKFIKTPPGVSAPTEPLLCKFADGGQKKRQNPNKYIPNGRPWPRDGE---AGMTLTYDPTTAALHNGFYP-SPYSIATNRMITQTSLTPYIASPVSAYQVQSPSWMQPQPYILQHPGAVLTPSMEHTMSLQPASMISPLAQQMSHLSLGST----GTYMP--ATSAMQGAYLP---QYTHMQTAAVPVEEASGQQQVAVETSNDHSPYTFPPNK---", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P29558-1", "uniprot_id": "RBMS1_HUMAN", "id": "P29558-1", "name": "RNA-binding motif, single-stranded-interacting protein 1", "aln": "------------------------------------------------------------------------------------------------------------------------------------MGKVWKQQMYPQYATYYYPQYLQAKQSLVPAHP----------------------MAPPSPSTTSSNNNSSSSS---------------------------NSGWDQLSKTNLYIRGLPPHTTDQDLVKLCQPYGKIVSTKAILDKTTNKCKGYGFVDFDSPAAAQKAVSALKASGVQAQMAKQQEQDPTNLYISNLPLSMDEQELENMLKPFGQVISTRILRDSSGTSRGVGFARMESTEKCEAVIGHFNGKFIKTPPGVSAPTEPLLCKFADGGQKKRQNPNKYIPNGRPWHREGEVRLAGMTLTYDPTTAAIQNGFYP-SPYSIATNRMITQTSITPYIASPVSAYQVQSPSWMQPQPYILQHPGAVLTPSMEHTMSLQPASMISPLAQQMSHLSLGST----GTYMP--ATSAMQGAYLP---QYAHMQTTAVPVEEASGQQQVAVETSNDHSPYTFQPNK---", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "E7FAG7-1", "uniprot_id": "E7FAG7_DANRE", "id": "E7FAG7-1", "name": "", "aln": "--------------------------------------------------------------------------------------------------------------------------------------MIFANTANPLRT----PSYRKQPPVAPPTLP----------------------MAPPSPSTNSSTNNSSSSSS--------------------------TTGWEQLSKTNLYIRGLPPGTTDHDLVKLCQPYGKIVSTKAILDKTTNKCKGYGFVDFDSPVSAQKAVAALKTNGVQAQMAKQQEQDPTNLYLSNLPVSMDEQELENLLKPFGQVVSTRILRDTNGMSRGVGFARMESTEKCDAVISHFNGKFIKSSSGMLGASEPLLCKFADGGQKKRQSQAKYIPNGRTWTRDAEVRLSGMTLTYDPNT-ALQNGYYA-APYAMG-NRLMTQPGVSPYIS-PISTYPVQNPSWMPHQPYIMQHPGAVLSPSMEHPMSLQPSAMLAPLTQQMGHLSLGGT----ATFIP--ANTAMPGAYIP---HYTHIQPPAIPPEQESGVQPQDVSSS-DPSSYPFQPNKQ--", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q8MSV2-5", "uniprot_id": "SHEP_DROME", "id": "Q8MSV2-5", "name": "Protein alan shepard", "aln": "MHPRYSPAPPPQQQQQMGGPPHQQQGGGGGGGVSMRGPSNAQQLPPQIPRSQNYSNGSSSSAAAAPLTSRSAFPGAPLTASAVALKGALPQRPPAMTSPAAAAAGAALAAGAPYRGAASWTPQGYAPAAAAAAAAVAQQAAYRYTAPLPQPAYAAYTPHTATTPATTTVSFLSQPVDYYWYGQRVPTAASPSNTNSSSSSNTGSQSGTLSTSLSNTTNTNTNMGPNGTVQNQNQQGGEQLSKTNLYIRGLQQGTTDKDLVNMCAQYGTIISTKAILDKTTNKCKGYGFVDFEQPAFAECAVKGLQGKGVQAQMAKQQEQDPTNLYIANLPPHFKETDLEAMLSKYGQVVSTRILRDQQMNSKGVGFARMESREKCEQIIQMFNGNTIP------GAKDPLLVKFADGGPKKKNLFKTPDPNARAWRDVSA---EGIPVAYDPTMQQNGVSVNVGTPIGVPYSRFSAPQVGGYPVAGSQWIPGYMMTQVDDQTSYSPQYMQMAAAPPLG-VTSYKPEAVNQVQPRGISMMVSGDTGVPYGTMMPQLATLQIGNSYISPTYPYYAPPPTIIPTMPMTDSEQASTAASPDEAYTQYPHQAAPK", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : : * * .: . *.** :..**..*:.*.* * :************ ***:***::* **.*:********:************:.*. *: ** .*: .******************::*** :.* :** :*. :***:***:*** . *:********* ***: :* ***: * ...:*** ****** **:: . **.*.* . *:.::***. . :* .: .*: : :: . .. .* *: . :*.: * :* :: .: :. : *.* .* :* *. : .:*:. * .. :* :. : . :* * : : : ", "identical_positions": 146, "similar_positions": 105, "identity": "24.33%" }, { "cls_id": "homologset.agr.MGI:1861776", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A0G2JYJ7-1", "uniprot_id": "A0A0G2JYJ7_RAT", "id": "A0A0G2JYJ7-1", "name": "", "aln": "--------------------------------------------------------------MLLSVTSR-----------------------PGIST------------------------FGYNKNNKKLYV--AQQMAP----------------------------------------------PSPRNGTPNSSS--------------------------------GSGGNDQLSKTNLYIRGLQPSTTDQDLVKLCQPYGKIVSTKAILDKTTNKCKGYGFVDFDSPSSAQKAVTALKASGVQAQMAKQQEQDPTNLYISNLPLSMDEQELEGMLKPFGQVISTRILRDTTGASRGVGFARMESTEKCEAIITHFNGKYIKTPPGVAAPSDPLLCKFADGGPKKRQNQGKFVQNGRAWPRNGDMGGMALTYDPTTALQNGFYT---APYSLAHSRMLAQSALAPYLPSPVSSYQRVTQTSPVQVPNTSWMQQQSYLMQPSGSVLTPGMDHPLSLQPASMMGPLTQQLGHLSLNSLGTFMPAAAAMQG--TYIS----QYPAVPSSSVSVEESNGQQSQLAVEPPSDHGVYPFQFSK-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8VC70-1", "uniprot_id": "RBMS2_MOUSE", "id": "Q8VC70-1", "name": "RNA-binding motif, single-stranded-interacting protein 2", "aln": "--------------------------------------------------------------MLLSVTSR-----------------------PGIST------------------------FGYNKNNKKLYV--AQQMAP----------------------------------------------PSPRNSTPNSSGGGGG----------------------------GSGGNDQLSKTNLYIRGLQPGTTDQDLVKLCQPYGKIVSTKAILDKTTNKCKGYGFVDFDSPSSAQKAVTALKASGVQAQMAKQQEQDPTNLYISNLPLSMDEQELEGMLKPFGQVISTRILRDTSGASRGVGFARMESTEKCEAIITHFNGKYIKTPPGVAAPSDPLLCKFADGGPKKRQSQGRYVQNGRAWPRNGDMGGMALTYDPTAALQNGFYA---APYSIAHSRMLAQSALAPYLPSPVSSYQ--------------------------GSVLTPGMDHPLSLQPASMMGPLTQQLGHLSLNSLGTFMPAAAAMHG--AYIS----QYPAVPSSSVSAEESNGQQNQLAVEPPSDHGVYPFQFSK-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q15434-1", "uniprot_id": "RBMS2_HUMAN", "id": "Q15434-1", "name": "RNA-binding motif, single-stranded-interacting protein 2", "aln": "--------------------------------------------------------------MLLSVTSR-----------------------PGIST------------------------FGYNRNNKKPYVSLAQQMAP----------------------------------------------PSPSNSTPNSSS--------------------------------GSNGNDQLSKTNLYIRGLQPGTTDQDLVKLCQPYGKIVSTKAILDKTTNKCKGYGFVDFDSPSAAQKAVTALKASGVQAQMAKQQEQDPTNLYISNLPLSMDEQELEGMLKPFGQVISTRILRDTSGTSRGVGFARMESTEKCEAIITHFNGKYIKTPPGVPAPSDPLLCKFADGGPKKRQNQGKFVQNGRAWPRNADMGVMALTYDPTTALQNGFYP---APYNITPNRMLAQSALSPYLSSPVSSYQRVTQTSPLQVPNPSWMHHHSYLMQPSGSVLTPGMDHPISLQPASMMGPLTQQLGHLSLSSTGTYMPTAAAMQG--AYIS----QYTPVPSSSVSVEESSGQQNQVAVDAPSEHGVYSFQFNK-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8MSV2-5", "uniprot_id": "SHEP_DROME", "id": "Q8MSV2-5", "name": "Protein alan shepard", "aln": "MHPRYSPAPPPQQQQQMGGPPHQQQGGGGGGGVSMRGPSNAQQLPPQIPRSQNYSNGSSSSAAAAPLTSRSAFPGAPLTASAVALKGALPQRPPAMTSPAAAAAGAALAAGAPYRGAASWTPQGYAPAAAAAAAAVAQQAAYRYTAPLPQPAYAAYTPHTATTPATTTVSFLSQPVDYYWYGQRVPTAASPSNTNSSSSSNTGSQSGTLSTSLSNTTNTNTNMGPNGTVQNQNQQGGEQLSKTNLYIRGLQQGTTDKDLVNMCAQYGTIISTKAILDKTTNKCKGYGFVDFEQPAFAECAVKGLQGKGVQAQMAKQQEQDPTNLYIANLPPHFKETDLEAMLSKYGQVVSTRILRDQQMNSKGVGFARMESREKCEQIIQMFNGN------TIPGAKDPLLVKFADGGPKKKNLFKTPDPNARAW-RDVSAEGIPVAYDP-TMQQNGVSVNVGTPIGVPYSRFSAPQVGG----YPVAGSQWIPGYMMTQVDDQTS-YSPQYMQMAAAPPLGVTSYKPEAVNQVQPRG-ISMMVSGDTGVPYGTMMPQLATLQIGNSYISPTYPYYAPPPTIIPTMPMTDSEQASTAASPDEAYTQYPHQAAPK", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .:*** *.::: ** . *** * .** * ...**. .. *.:************* .***:***::* **.*:*********************:.*: *: **..*:..*******************:*** :.* :**.**. :***:******* *:********* **** ** ***: :....**** *********:: *.*** *: . :.::*** : ***. :* .:. .*: * .. . **:. * .. * :* ::: .. * :: :. : . ** ** *::: :*** *.. *: : :..:* . *... . : *..* ", "identical_positions": 168, "similar_positions": 102, "identity": "27.81%" }, { "cls_id": "homologset.agr.MGI:1861899", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9JJ16-1", "uniprot_id": "5HT3B_RAT", "id": "Q9JJ16-1", "name": "5-hydroxytryptamine receptor 3B", "aln": "-----MILLWSCLLVAVVGILGTATPQPGNSSLHRLTRQLLQQYHKEVRPVYNWAEATTVYLDLCVHAVLDVDVQNQKLKTSMWYREVWNDEFLSWNSSLFDDIQEISLPLSAIWAPDIIINEFVDVERSPDLPYVYVNSSGTIRNHKPIQVVSACSLQTYAFPFDIQNCSLTFNSILHTVEDIDLGFLRNQEDIENDKRSFLNDSEWQLLSVTSTYHIRQSSAGDFAQIRFNVVIRRCPLAYVVSLLIPSIFLMLVDLGSFYLPPNCRARIVFKTNVLVGYTVFRVNMSDEVPRSAGCTSLIGVFFTVCMALLVLSLSKSILLIKFLYEERHSEQERPLMCLRGDSDANESRLYLRAPCAEDTESPVRQEHQVPSDTLKDFWFQLQSINNSLRTRDQVYQKEVEWLAILCHFDQLLFRIYLAVLGLYTVTLCSLWALWSRM", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9JHJ5-1", "uniprot_id": "5HT3B_MOUSE", "id": "Q9JHJ5-1", "name": "5-hydroxytryptamine receptor 3B", "aln": "-----MILLWSCLLVAVVGILGTATPQPGNSSLHRLTRQLLQQYHKEVRPVYNWAEATTVYLDLCVHAVLDVDVQNQKLKTSVWYREVWNDEFLSWNSSLFDEIQEISLPLSALWAPDIIINEFVDVERSPDLPYVYVNSSGTIRNHKPIQVVSACSLQTYAFPFDIQNCSLTFNSILHTVEDIDLGFLRNREDIENDKRAFMNDSEWQLLSVSSTYHIRQSSAGDFAQIRFNVVIRRCPLAYVVSLLIPSIFLMLVDLGSFYLPPNCRARIVFKTNVLVGYTVFRVNMSDEVPRSAGCTPLIGVFFTVCMALLVLSLSKSILLIKFLYEERHSGQERPLMCLQGDSDAEESRLYLGAPRADVTESPVHQEHRVPSDTLKDFWFQFRSINNSLRTRDQIHQKEVEWLAILYRFDQLLFRIYLAVLGLYTVTLCSLWALWSRM", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O95264-1", "uniprot_id": "5HT3B_HUMAN", "id": "O95264-1", "name": "5-hydroxytryptamine receptor 3B", "aln": "MLSSVMAPLWACILVAAG-ILATDTHHPQDSALYHLSKQLLQKYHKEVRPVYNWTKATTVYLDLFVHAILDVDAENQILKTSVWYQEVWNDEFLSWNSSMFDEIREISLPLSAIWAPDIIINEFVDIERYPDLPYVYVNSSGTIENYKPIQVVSACSLETYAFPFDVQNCSLTFKSILHTVEDVDLAFLRSPEDIQHDKKAFLNDSEWELLSVSSTYSILQSSAGGFAQIQFNVVMRRHPLVYVVSLLIPSIFLMLVDLGSFYLPPNCRARIVFKTSVLVGYTVFRVNMSNQVPRSVGSTPLIGHFFTICMAFLVLSLAKSIVLVKFLHDEQRGGQEQPFLCLRGDTDADRPRVEPRAQRAVVTESSLYGEHLAQPGTLKEVWSQLQSISNYLQTQDQTDQQEAEWLVLLSRFDRLLFQSYLFMLGIYTITLCSLWALWGGV", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * **:*:***. **.* * :* :*:*::*::****:***********::******** ***:****.:** ****:**:*************:**:*:********:************:** **************.*:***********:*******:*******:********:**.***. ***::**::*:*****:****:*** * *****.****:****:** **.**********************************.*************::****.*.*.*** ***:***:*****:***:*:***::*::. **:*::**:**:**:..*: * * ***.: ** . ..***:.* *::**.* *:*:** *:*.***.:* :**:***: ** :**:**:*********. :", "identical_positions": 310, "similar_positions": 92, "identity": "70.14%" }, { "cls_id": "homologset.agr.MGI:1861901", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q810W7-1", "uniprot_id": "MAST1_RAT", "id": "Q810W7-1", "name": "Microtubule-associated serine/threonine-protein kinase 1", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSDSLWTALSNFSMPSFPGGSMFR-------------------------------------------RTKSCRTSNRKSLILTSTSPTLPR--PHSPLPGH-------------------------------------------------------------LGSSPLDSPRNFSPN------TPAHFSFASSRRA--------DGRRWSLASLPSSGYGTNTPSSTVSSSCSSQERLHQLPY---------------------------------------------QP---------------TVDELHFLSKHFG----------------STESITDEDGGRRSPAVRPRSRSLSPGRSPSSYDNEIVMMNHVYKERFPKATAQMEEKLRDFARAYEPDSVLPLADG--VLSFIHHQIIELARDCLTKSRDGLITTVYFYELQENLEKLLQDAYERSESLEVAFVTQLVKKLLIIISRPARLLECLEFNPEEFYHLLEAAEGHAKEGHLVKTDIPRYIIRQLGLTRDPFPDVVRLE---------------------------------------------EQDSG-GSNTPE------------------------------------------------QDDTSEGRSSTSKAKKPPGESDFDTIKLISNGAYGAVYLVRHRDTRQRFAMKKINKQNLILRNQIQQAFVERDILTFAENPFVVGMFCSFETRRHLCMVMEYVEGGDCATLLKNIGALPVEMARMYFAETVLALEYLHNYGIVHRDLKPDNLLITSMGHIKLTDFGLSKMGLMSLTTNLYEGHIEKDAREFLDKQVCGTPEYIAPEVILRQGYGKPVDWWAMGIILYEFLVGCVPFFGDTPEELFGQVISDDILWPEG-DEALPTDAQLLISSLLQTNPLVRLGAG-GAFEVKQHSFFRDLDWTGLLRQKAEFIPHLESEDDTSYFDTRSDRYHHVNSYDEDDTTEEEPVEIRQFSSCSPRFSKVYSSMEQLSQHEPKTPVSASGASKRDPNAKGPEEKVAGKREGLGGLTLREKTWRGGS-------------------------PEIKRFSASEASFLEGEA-----------SPPLGARRRFSALLE-------------PSRFTAPQEDEDEARLRRPPRPSSDPP--SSLDTRVPKEAAQGE-----GTSTPGEPEATERSHPGDFCPPSKD---------------GDPSGPRATNDLVLRRAR------HQQLSGDLSVEKRPS-RTGGK-VIKSASATALSVMIPAVDPHGGSPLASPMSPR---SLSSNPSSRDSSPSRDYSPAVSGLRSPITIQRSGKKYGFTLRAIRVYMGDSDVYSVHHIVWHVEEGGPAQEAGLCAGDLITHVNGEPVHGMVHPEVVELILKSGNKVAVTTTPFENTSIRIGPARRSSYKAKMARR---NKRPSAKDGQESKKRSSLFRKIT-KQSNLLHTSRSLSSLNRSLSSSDSLPGSPTHGLPARSPTHSYRSTPDSAYLGASSQSSSPASSTPNSPASSASHHIRPSTLHGLSPKLHRQYRSARCKSAGNIPLSPLAHTPSPTQASPPPLPGHTVGSSHTTQSFPAKLHSSPPIVRPRPKSAEPPRSPLLKRVQSAEKLG-----ASLGADKK---GALRKHSLEVGHPDFRKD-FHGELALHSLAESDGETPPIEGPGATRQ-------------VAMRRLGRQESPLSLG----ADPLLPDGVQRPMASGKE-DSAGG-----TEACTPPRATTPGSRTLERDLG-----------------------CTRHQSVQTEDGPGGVARALAK------------------------------------AALSPVQEH-------------------ETGRRSSSGEAGTPPVP----IVVEPARPGVKTQTPQPLGTDSKGLKEPVAQIP----------LVPDAP-----------------------RV----RERWVLEEVEERTTLSGPRSKPASPKLS---PDPQTPTVAPTKN-VPRSAAPPVPPASLMVPGTKPEAGSNSRCPAEGVASAGLTKTGAPSPASLGP--------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9R1L5-1", "uniprot_id": "MAST1_MOUSE", "id": "Q9R1L5-1", "name": "Microtubule-associated serine/threonine-protein kinase 1", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSDSLWTALSNFSMPSFPGGSMFR-------------------------------------------RTKSCRTSNRKSLILTSTSPTLPR--PHSPLPGH-------------------------------------------------------------LGSSPLDSPRNFSPN------TPAHFSFASSRRA--------DGRRWSLASLPSSGYGTNTPSSTVSSSCSSQERLHQLPY---------------------------------------------QP---------------TVDELHFLSKHFG----------------STESITDEDGGRRSPAVRPRSRSLSPGRSPSSYDNEIVMMNHVYKERFPKATAQMEEKLRDFARAYEPDSVLPLADG--VLSFIHHQIIELARDCLTKSRDGLITTVYFYELQENLEKLLQDAYERSESLEVAFVTQLVKKLLIIISRPARLLECLEFNPEEFYHLLEAAEGHAKEGHLVKTDIPRYIIRQLGLTRDPFPDVVRLE---------------------------------------------EQDSG-GSNTPE------------------------------------------------QDDTSEGRSSTSKAKKPPGESDFDTIKLISNGAYGAVYLVRHRDTRQRFAMKKINKQNLILRNQIQQAFVERDILTFAENPFVVGMFCSFETRRHLCMVMEYVEGGDCATLLKNIGALPVEMARMYFAETVLALEYLHNYGIVHRDLKPDNLLITSMGHIKLTDFGLSKMGLMSLTTNLYEGHIEKDAREFLDKQVCGTPEYIAPEVILRQGYGKPVDWWAMGIILYEFLVGCVPFFGDTPEELFGQVISDDILWPEG-DEALPTDAQLLISSLLQTNPLVRLGAG-GAFEVKQHSFFRDLDWTGLLRQKAEFIPHLESEDDTSYFDTRSDRYHHVNSYDEDDTTEEEPVEIRQFSSCSPRFSKVYSSMEQLSQHEPKTPVSASGASKRDPSAKGPEEKVAGKREGLGGLTLREKTWRGGS-------------------------PEIKRFSASEASFLEGEA-----------SPPLGARRRFSALLE-------------PSRFTAPQEDEDEARLRRPPRPSSDPP--SSLDTRVPKEAVQGE-----GTSTPGEPEATERSHPGDLGPPSKD---------------GDPSGPRATNDLVLRRAR------HQQLSGDLAVEKRPS-RTGGK-VIKSASATALSVMIPAVDPHGGSPLASPMSPR---SLSSNPSSRDSSPSRDYSPAVSGLRSPITIQRSGKKYGFTLRAIRVYMGDSDVYSVHHIVWHVEEGGPAQEAGLCAGDLITHVNGEPVHGMVHPEVVELILKSGNKVAVTTTPFENTSIRIGPARRSSYKAKMARR---NKRPSAKDGQESKKRSSLFRKIT-KQSNLLHTSRSLSSLNRSLSSSDSLPGSPTHGLPARSPTHSYRSTPDSAYLGASSQSSSPASSTPNSPASSASHHIRPSTLHGLSPKLHRQYRSARCKSAGNIPLSPLAHTPSPTQASPPPLPGHTVGSSHTTQSFPAKLHSSPPVVRPRPKSAEPPRSPLLKRVQSAEKLG-----ASLGADKK---GALRKHSLEVGHPDFRKD-FHGELALHSLAESDGETPPIEGPGATRQ-------------VAVRRLGRQESPLSLG----ADPLLPDGVQRPMASSKE-DSAGG-----TEACTPPRATTPGSRTLERDSG-----------------------CTRHQSVQTEDGPGGVARALAK------------------------------------AALSPVQEH-------------------ETGRRSSSGEAGTPPVP----IVVEPARPGVKTQAPQPLGTDSKGLKEPVAQMP----------LMPDAP-----------------------RG----RERWVLEEVEERTTLSGLRSKPASPKLS---PDPQTPTLVPTKN-VPRSAAPSVPPASLMVPGTKPEAGLNSRCPAEAVTPAGLTKTGAPSPASLGP--------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9Y2H9-1", "uniprot_id": "MAST1_HUMAN", "id": "Q9Y2H9-1", "name": "Microtubule-associated serine/threonine-protein kinase 1", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSDSLWTALSNFSMPSFPGGSMFR-------------------------------------------RTKSCRTSNRKSLILTSTSPTLPR--PHSPLPGH-------------------------------------------------------------LGSSPLDSPRNFSPN------TPAHFSFASSRRA--------DGRRWSLASLPSSGYGTNTPSSTVSSSCSSQERLHQLPY---------------------------------------------QP---------------TVDELHFLSKHFG----------------STESITDEDGGRRSPAVRPRSRSLSPGRSPSSYDNEIVMMNHVYKERFPKATAQMEEKLRDFTRAYEPDSVLPLADG--VLSFIHHQIIELARDCLTKSRDGLITTVYFYELQENLEKLLQDAYERSESLEVAFVTQLVKKLLIIISRPARLLECLEFNPEEFYHLLEAAEGHAKEGHLVKTDIPRYIIRQLGLTRDPFPDVVHLE---------------------------------------------EQDSG-GSNTPE------------------------------------------------QDDLSEGRS--SKAKKPPGENDFDTIKLISNGAYGAVYLVRHRDTRQRFAMKKINKQNLILRNQIQQAFVERDILTFAENPFVVGMFCSFETRRHLCMVMEYVEGGDCATLLKNIGALPVEMARMYFAETVLALEYLHNYGIVHRDLKPDNLLITSMGHIKLTDFGLSKMGLMSLTTNLYEGHIEKDAREFLDKQVCGTPEYIAPEVILRQGYGKPVDWWAMGIILYEFLVGCVPFFGDTPEELFGQVISDDILWPEG-DEALPTEAQLLISSLLQTNPLVRLGAG-GAFEVKQHSFFRDLDWTGLLRQKAEFIPHLESEDDTSYFDTRSDRYHHVNSYDEDDTTEEEPVEIRQFSSCSPRFSKVYSSMEQLSQHEPKTPVAAAGSSKREPSTKGPEEKVAGKREGLGGLTLREKTWRGGS-------------------------PEIKRFSASEASFLEGEA-----------SPPLGARRRFSALLE-------------PSRFSAPQEDEDEARLRRPPRPSSDPA--GSLDARAPKEETQGE-----GTSSAGDSEATDRPRPGDLCPPSKD---------------GDASGPRATNDLVLRRAR------HQQMSGDVAVEKRPS-RTGGK-VIKSASATALSVMIPAVDPHGSSPLASPMSPR---SLSSNPSSRDSSPSRDYSPAVSGLRSPITIQRSGKKYGFTLRAIRVYMGDTDVYSVHHIVWHVEEGGPAQEAGLCAGDLITHVNGEPVHGMVHPEVVELILKSGNKVAVTTTPFENTSIRIGPARRSSYKAKMARR---NKRPSAKEGQESKKRSSLFRKIT-KQSNLLHTSRSLSSLNRSLSSSDSLPGSPTHGLPARSPTHSYRSTPDSAYLGASSQSSSPASSTPNSPASSASHHIRPSTLHGLSPKLHRQYRSARCKSAGNIPLSPLAHTPSPTQASPPPLPGHTVGSSHTTQSFPAKLHSSPPVVRPRPKSAEPPRSPLLKRVQSAEKLG-----ASLSADKK---GALRKHSLEVGHPDFRKD-FHGELALHSLAESDGETPPVEGLGAPRQ-------------VAVRRLGRQESPLSLG----ADPLLPEGASRPPVSSKEKESPGG-----AEACTPPRATTPGGRTLERDVG-----------------------CTRHQSVQTEDGTGGMARAVAK------------------------------------AALSPVQEH-------------------ETGRRSSSGEAGTPLVP----IVVEPARPGAKAVVPQPLGADSKGLQEPAPLAP----------SVPEAP-----------------------RG----RERWVLEVVEERTTLSGPRSKPASPKLS---PEPQTPSLAPAKCSAPSSAVTPVPPASLLGSGTKPQVGLTSRCPAEAVPPAGLTKKGVSSPAPPGP--------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M3AXQ6-1", "uniprot_id": "A0A8M3AXQ6_DANRE", "id": "A0A8M3AXQ6-1", "name": "non-specific serine/threonine protein kinase", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------MDDSGIIRRRRLQ-----DLPLPR-------------------------------------------KNSSCR-SNRKSLILTSTSPTLPR--PHSPLPGH-------------------------------------------------------------IGSSPLDSPRNFSPS------TPAHFSFASSRR---------DGRRWSLASLPSSGYGTNTPSSTSSS--SSQERLHQLPS---------------------------------------------QP---------------TMDELHFLSKHFG----------------STESITDDDGGRCSPHIRPRSRSLSPGRSHSCYDNEIIMMNHVYRERFPKATAQMEGRLCDFVHSYCPENVLPLADG--VLSFIHHQIIELSRDCLTKSREGLITSVYFFELQENLEKLLDDAYKRSESSELTFVTELVKKIFFIIARPARLLECLEFNPEEFYHLLEAAEDHAKEGHLMKTDIPRYIISQLGLTRDPLEEMVSRE---------------------------------------------HYDSE-GPVTPE------------------------------------------------TDDSAEGKM---KPMKPPGEADFQTIKLISNGAYGEVYLVRHLETRQRFAMKKINKQNLILRNQIQQAFVERDILTFAENPFVVSMFCSFETRRHLCMVMEYVEGGDCATLLKNIGALPVEMARMYFAETVLALEYIHNYGIVHRDLKPDNLLITSMGHIKLTDFGLSKMGLMSLTTNLYEGHIEKDTREFLDKQVCGTPEYIAPEVILRQGYGKPVDWWAMGIILYEFLVGCVPFFGDTPEELFGQVISDDIVWPED-DDALPPDAQHLISSLLQTSPLLRLGTG-GAFEVKQHPFFGDLDWGSLLRQKAEFIPNLESEEDTSYFDTRSERYHHVHSYDEDDTNDDEPVEIHRFSSCSPRFSKVYSSMEHLSQLEHK-PVVTR----REP--KPHRED-RAKRESMGSLTLRDKTWRTGS-------------------------PEMKRLSCSESSFTESDS-----------SPP-GARRRFSALMD-------------THRFASPLEGDSDTHTRQPPVKTRGTSLEGASVPVSSGLFESSS-----AVSVGHPGDKLLRPAEGPSAPLHMP----------------EPFSARVGSDLVLRRAR------HHQIPSDS--EKRTATRSGTK-VIKSASATALSVIIPAVEQHGTSPLASPMSPR---SVSSNPSSRDSSPSRDYSPTVNVLRSPITIHRSGKKYGFTLRAIRVYMGDSHVYSVHHMVWHVECGGPAQEAGLCAGDLITHVNGEPVHGLVHTEVVELILKSGSKVTVTTTPFENTSIKIGPARKLSYKAKMARR---NKKSAAKDGQESKKRSSLFRKIT-KQSNLLHTSRSLSSLNRSLSSGDSLPGSPTHNLSARSPTQTYRSPPDSTYLGTSSQSSSPASSTPNSPAT--SQHMRPSSLYGLSPKLHRQYRSARCKSAGNIPLSPLAHTPSPTSSSPPPIAGHIVGSSNTTQAFPAKLHASPPITRPRPKSAEPPRSPLLQRVQSAEKLGPPSPPSSSSSDRKGGLG-IRKHGLDVVHAEYRRESFHCEHALQSLMEIEGENTPSALP-SPPDQTPTHMPIKH-TLSPARQLGRQDSIMDR--EFEGKSKQADSSEAILKTASKTEP---------VAIIVDLKSTPLGETTQRDK-----------------------VASKFESSQVS--VASMGKVVAKDVGKIESSSTLVTG-------PKIPDWTPIVQSSGVQELKPHQTESPKGLENG----------KDIGKIPVKEKTQLTKTP-------EASKSSKGPLNVEGTGSGSIG-TPKVSEA------------VPSQS---------KSIQERAQTPSGSTRG--PQEERCRLEAVEVSPPSPSPIARSPCTSKSRAISPGDRSSFVTQLTSVAKTVLGPMKLGSQDGGKAKDSSKTNEDKRAATLGKSEASSGGRRGLTGTWPGPGSSSKPEKASKSSSKHS-", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8M3AKH8-1", "uniprot_id": "A0A8M3AKH8_DANRE", "id": "A0A8M3AKH8-1", "name": "non-specific serine/threonine protein kinase", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------MSDSMDDSGIIRRRRMQK----DLPLPR-------------------------------------------KSSGCRTSNRKSLILTSTSPTLPR--PHSPLPGH-------------------------------------------------------------IGSSPLDSPRTFSPS------APAHFSFASSRRA--------DGRRWSLASLPSSGYGTNTPSSTSSS--SSQERLHQLPF---------------------------------------------QP---------------TLDELHFLTKHFG----------------STESITDDDG-RRSPHMRPRSRSLSPGRSSSCYDNEIVMMNHVYKERFPKATAQMEERLADFIESYSPENVLPLADG--VLSFIHHQIAELSRNCLTKSREGLITTVYFYELQENLEKLLHEAYERSESSELTFITELVKKLFIIISRPARLLECLEFNPEEFYHLLEAAEDHAKEGQLMKADIPRYIISQLGLTRDPLEDMVNLE---------------------------------------------SYDSE-GPHTPE------------------------------------------------TDDSAEGKL---KAIKPPCESDFQTIKLISNGAYGAVYLVRHRETRQRFAMKKINKQNLILRNQIQQAFVERDILTFAENPFVVSMFCSFETRRHLCMVMEYVEGGDCATLLKNIGALPVDMARMYFAETVLALEYIHNYGIVHRDLKPDNLLITSMGHIKLTDFGLSKMGLMNLTTNLYEGHIEKDAREFLDKQVCGTPEYIAPEVILRQGYGKPVDWWAMGIILYEFLVGCVPFFGDTPEELFGQVITDYIEWPNG-DEALPADAQSLISSLLQTNPLVRLGTG-GAFEVKQHSFFSGLDWNGLLRQKAEFIPHLESEEDTSYFDTRSERYRHINSYDEDDTNDDEPVEIRQFSSCSPRFSKVYSSMEHLSQLEQKTPVVTR----REH--KGRRDDKITKRESFGSFSMRDKSWRTGS-------------------------PEMKRLSCSESLYMEGDC-----------SPPMGARRRFSALMD-------------THRFASSQEGDGE---RQVTAKATGSS-EGAVPPSSPSANEQRNGKEVMSISSSKSTDKASRPGE-VSAPQTIPSTGAPAVISRDLVAIGDPVGQRATKDLVLRRAR------HQQLSSDG--EKRTS-RPGNK-VIKSASATALSVIIPGVEQHGNSPLASPMSPR---SLSSNPSSRDSSPSRDYCPTVTVPRSPITIQRSGKKYGFTLRAIRVYIGDTDVYSVHHIVWHVEDGGPAQEAGLCAGDLITHVNGESVHGLVHTEVVELILKSGNKVTVTTTPFENTSIKVGPARRSSYKSKMARR---SKR-TVKEGQESKRRGSLFRKIT-KQSNLLHTSRSLSSLNRSLSSSDSLPGSPTHSLSGHSPTQSYRSTPESSHLGASSQSSSPASSTPNSPAT--TQHMRPSSLHGLSPKLHRQYRSARCKSAGNIPLSPLAHTPSPTQSSPPPLPGHTVGSSNTTQTFPAKLHSSPPIIRPRPKSAEPPRSPLLKRVQSAEKLG---SPLSSSSEKKGGIGVMRKHSLEVGHSDYRKDGFHCELGLQSLVEIEGENLASAPTNSPSPTQPTPLPPETGVLKPVRKLGRQESPLSRDALLAGRERERERERERERTGKANEPSRPTESKPAAVTPPGSKTSPNSETSQRHTSTIQECCLVKPQTWQPPLTKSSPIASESKSNIVTSIPSPLTTVSSPSTKTIDQSSIREEGNDDKGSLTKIPQSQTLGTTKSPLSLIPSELINKDLLEKGGNDNGKKQVKSDVGNTSAQGKPSIPCSPPVKTTSTEVTKANEGFGNGDSLKKGVLDPHSRTSDVRVRTALAPSKGLVPSHPPQTQCSALGKLRQDKGLSAVSCYRGSFDWEDKCLLEVVEEHSPSPTPSPTGVPPDLLKSQPPAERTGLVTHLTSTGKS-IGAVKGGTQEGPKAKDTNKSLEITQACAPGRPESSPEGRPNSKGASP---TSSSPQVKTLITPKNGS", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VUQ9-1", "uniprot_id": "Q9VUQ9_DROME", "id": "Q9VUQ9-1", "name": "non-specific serine/threonine protein kinase", "aln": "MSRQEGAASRPADGATGPVASSSSSTSSNHSVSAVLGSKISTSTPQKNDEHQEQEFINQSVASEIEAMSISDSASAESSSGATATATATMSGSPVPKRHLSTANLSRIRPQSSYSARVLIFDDSDQEAAAAAAALAAASSSCNSSVKSCSGLELLPTSPAKLSIGNDSTNGSSMMRNLNLTKSSSGGLSGSSSSLHSRGYTALLRKISYQQHTNSLRAVSGETSNLLRMRHSSLGKSAPCLTGNYFRHELTAPLPVQPPGFGASPLGGHNISRSGSCAGIGLAKHHHHHHLHGVVMRGSAGGGAGSGGGSSSGVAHHRLSLVTNSAAVAAAGGSRTHSPYSASPVDSPRLNSPMPFAFAPIKRIASCRGVVADGRRWSVASLPSSGYGTTPGSSNLSSQCSSQEGLNQLAHNIPPGVQEADAAAVAAGACCAEHLKQHCPKHCALLLAVSQKQLTPQPPKPTQLQPQKSMTAACVNCCAELSVTCGGQQAGGGAANGGSSANSSGSSAMQVGGRMSPYFRPRSRSLSSPSRSPIVDNEIAVMNTLYKERFPKATQQMEERLKLFINENKSAACNSFRDSQPIVRFVHHQVLEMARDCLHKSEAKLITSQYFYELSENLERLLVETKEKSPE-AAAELNGVIKKLLLIISRPARLLECLEFDPQEFYELLEAAEGHAKAMPVIKADIPQYIIHKLGLNRDPIAELQQELRETQQMCSEQVTVDADPLHPGGSLLLNSPLTSAAKQLSSLALDAIAMDSGSGTATPQQPPQTPVATCDTAPSFALAISQMNEEKGGSSSAVGGGSSSKVAGAEGITGGSAATATGSGAQQPSPQENDFDIVKLISNGAYGAVYLVKHKTTRQRFAMKKINKNNLILRNQVEQVFAERDILSFADNPFVVSMYCSFETKKHLCLVMEYVEGGDCGTLLKNIGPLPADMARFYFAETVLAVEYLHSYGIVHRDLKPDNLLITALGHIKLTDFGLSKMGLMSLATNLYEGYIDSETRQFSDKQVYGTPEYIAPEVILRQGYGKPVDWWSMGIILYEFLIGCVPFFGETTEELFAHTVNDDIEWPDSEDWPVQAEAKDIISQLLQQNPRDRLGTQSGALEMKEHEYFLGMDWNSLLRQKAEFVPQLSHDDDTSYFDTRMDRYNHDLGGEDTDDTDDTPVFG-SFNSYTPQYRKQHYSWSRHATPTSTDGAKPTGPPPLSSLPSRAQETPAATVGATSTGALPKLKSGMGSGSGSGSGSGSGSASHDGVVNKFLNTPQLRKLDLSSSCLKVPSTPDADYLPELLHNVTIGNDAELRMLKHYLQQPNPGATQRMQQRHSMPPNTTTIISTPATPPPTQTQATMAATPPTATVGSFSRSTPESSQTDSDDFSPQINRKRKGVCARDILPR------FSISIEDETISAGSSSTENMNLPREQSPLALQHQPKSMDGSTSGSSVKHHRSRSIVKSASALGLSLMTSLDNSQLAAQLCGIQSPGGGGNGSSTASSRDTSPCRELSPLVTNLKPPIIIRRGPRGFGFTVHTIRVYYGDTDFYTMHHLVMAVDEGSPAFEAGLRPADLITHVNGEAVQGLFHTQVLQLLLSGGEHVTLRATPLEHTSIQSGGRKRDLMQSKLAKKGVNRQKKQTKREHDKKRKTSLFRRISSKRANAEMQQYSAGTSSPTTPSARNLSPLDSSYHSSCCQSAAN-SSSQSTSPSSSSPNTPTGSSGSNHGGNAGSVAVAPSALSVQLPSAPPPTQLVLLPHVGAVVGSNPTSVGN-VPVSPTGVVPQLYQRPSTLHGLKHKLHAATAVIAGGGNANNPAGGLKTLHTTNNNSLP----NRRKSVGHIPLSPLARTPSPSPLPSSPTRSPSPLAFPLVGHQPGASNTTQSYSPGSTLP---------------TLQTAVNANTKKAG---FARTKSAEPSSPLLRRALSPDRLHPR---SAETKISPLCCSPPIKQPTHQRV----------------------VTTTWRSTPGGSASGAGGAVLGAP-------------------------------SVQPLQLVPAASE-------------------ESQRQTAMATVVSTTAAG----TDPSATAVVTLANCEPLPRIAEEKDSPTSTQD-------------SSS-----------------------------VSEGFMPAIEEFAEGESSSSPTQTLEKPTKVKATEQPEMEPAGKSKKVDQGKTTTPGTPKTKPHNSGCKTSMTTTKPASPSVTISTAPRKDTSAVTGGGSSGSGGSAATSAAKQRK-", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ..* .: . . :. * .* **:. *. * *** ** *.* .** . ** :* *:**. :* ******:**********.. **. ** **** *:**. ** :: *: * *: * : : * * ** .********. . **** :** :*:******* *** :* * . . .: *. :: *:***: *::*:** **. ***: **:**.****:** :: ::* . : :. ::**:::**:***********:*:***.******.*** ::*:***:*** :***.***: :: ** *. **: .. : .* * **: :********* ****:* ************:*******::*.*.*****:**:*****.*:*****::***:**********.*******.**.:***:********:**:*.****************::****************.*:******:*:.::*:* **** ***********************:*********:*******:*.****.:.:.* * **:. * .: .:*: :**.*** .* ***: **:*:*:* :* .:** .********:*:*. ::******** :**.* . :: * .:: ** *.* :*:: * : * .: : . . . . . .: . . . :: . . ** *:::::. *.: . . . * .: * . *.: . : . : . .: . . . . . * . . .:: * * : *: . * . . : : ::***** .**:: . : : : *.. ** . **..****:**.*: .* *. :.** *:*. : :***:::**** **:..*::**:* *: *.** **** ..*********.*:*:.*.:*::*:*..*.:*:: :**:*:***: * :: ::*:*:: :: .* ::.*:: ****:*: *::* . * .: . : .*. .*. : .. . : : *..:*: .:** .:...** .* .. : : **:* *. : . .* : * : . . . **. : : . * : : ***::..: :: :*. . :. . :.* . : *. . . .. :. * . .:. :. : . : . . . : . : . :* . :. : .* . . . * * : . . . . : . : .. . . .. : :* . . . : . . . . .: : : . ", "identical_positions": 517, "similar_positions": 424, "identity": "22.55%" }, { "cls_id": "homologset.agr.MGI:1861942", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A0G2KA15-1", "uniprot_id": "A0A0G2KA15_RAT", "id": "A0A0G2KA15-1", "name": "General transcription factor II-I repeat domain-containing protein 1", "aln": "MALLGKH-CDIPTNGCGSERWNSTFARKDELINSLVSALDSMCSALSKLNTEVACVAVHNESVFVMGTEKGRVFLNTRKELQSDFLRFCRGPLWNDPEAGHPK---------KVQRCEGGGRSIPRSSLEQCSDVYLLQKMVEEVFDVLYSEAMGRATVVPLPYERLLREPGLLAVQGLPEGLAFRRPAEYDPKALMAILEHSHRIRFKLRRPPDDGGQDTKALVEMNGISLLPKGSRDCGLHGQASKVSPQDLTPTATPSSMANFLYSTSMPNHTIRELKQEVPTCPLTPSDLGLGWP-VPEPHVPSTQDFSDCCGQ-APAGPAGPLIQN---VHASKRILFSIVHDKSEKWDPFIKEMEDINTLRECVQILFNSRYAEALGLDHMVPVPYRKIACDPEAVEIVGIPDKIPFKRPCTYGVPKLKRILEERHSIHFIIKRMFDERIFTGN-KFTKDPMKLEPASP----PEDTATEVCRDSMLDLAGTAWSDMSSVS--EDCGPGTSGEIGMLRPIKIEPEELDIIQVTVSDPSPTSEEMTDSLPGHLPSEDSGYGMEMPADKGPSEEPWQEERPAEESPGDVIRPLRKQVEMLFNTKYAKAIGTSEPVKVPYSKFLMHPEELFVLGLPEGISLRRPNCFGIAKLRKILEASNSIQFVIKRPELLTDGVKEPVMDTQ---------------ERDSWDPLVDETP--KRQGLQENYNTRLSRIDIANTLREQVQDLFNKKYGEALGIKYPVQVPYKRIKSNPGSVIIEGLPPGIPFRKPCTFGSQNLERILSVADKIKFTVTRPFQGLIPKP---------------------------DEDDANRLGEKVILREQVKELFNEKYGEALGLNRPVLVPYKLIRDSPDAVEVKGLPDDIPFRNPNTYDIHRLEKILKARDHVRMVIINQLQPFTEVCNDP-------------------------------------------------------------------------------------------------------KVPAKDN-IPKRKRKRVSEGNSVSSSSSSSSSSSSNPESVASTNQISLVQ------------WPVYMVDY-------SGLNVQLPGPLDY-------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9JI57-1", "uniprot_id": "GT2D1_MOUSE", "id": "Q9JI57-1", "name": "General transcription factor II-I repeat domain-containing protein 1", "aln": "MALLGKH-CDIPTNGCGSERWNSTFARKDELINSLVSALDSMCSALSKLNTEVACVAVHNESVFVMGTEKGRVFLNTRKELQSDFLRFCRGPLWNDPEAGHPK---------KVQRCEGGGRSLPRSSLEQCSDVYLLQKMVEEVFDVLYSEAMGRATVVPLPYERLLREPGLLAVQGLPEGLAFRRPAEYDPKALMAILEHSHRIRFKLRRPPDDGGQDTKALVEMNGISLLPKGSRDCGLHGQASKVAPQDLTPTATPSSMANFLYSTSMPNHTIRELKQEVPTCPLTPSDLGMGWP-VPEPHVPSTQDFSDCCGQ-TPAGPAGPLIQN---VHASKRILFSIVHDKSEKWDPFIKEMEDINTLRECVQILFNSRYAEALGLDHMVPVPYRKIACDPEAVEIVGIPDKIPFKRPCTYGVPKLKRILEERHSIHFIIKRMFDERIFTGN-KFTKDPMKLEPASP----PEDTSTEVCRDSMLDLAGTAWSDMSSVS--EDCGPGTSGEIAMLRPIKIEPEELDIIQVTVSDPSPTSEEMTDSLPGHLPSEDSGYGMEMPADKGPSEEPWSEERPAEESPGDVIRPLRKQVEMLFNTKYAKAIGTSEPVKVPYSKFLMHPEELFVLGLPEGISLRRPNCFGIAKLRKILEASNSIQFVIKRPELLTDGVKEPVLDTQ---------------ERDSWDRLVDETP--KRQGLQENYNTRLSRIDIANTLREQVQDLFNKKYGEALGIKYPVQVPYKRIKSNPGSVIIEGLPPGIPFRKPCTFGSQNLERILSVADKIKFTVTRPFQGLIPKPETKILTTGHEAGKTTRPRRLQQDTWQPDEDDANRLGEKVILREQVKELFNEKYGEALGLNRPVLVPYKLIRDSPDAVEVKGLPDDIPFRNPNTYDIHRLEKILKAREHVRMVIINQLQPFAEVCNDPKVPEEDDSNKLGKKVILREQVKELFNEKYGEALGLNRPVLVPYKLIRDSPDAVEVKGLPDDIPFRNPNTYDIHRLEKILKAREHVRMVIINQLQPFGDVCNNAKVPAKDN-IPKRKRKRVSEGNSVSSSSSSSSSSS-NPESVASTNQISLVVKSRGSELHPNSVWPLPLPRAGPSTAPGTGRHWALRGTQPTTEGQAHPLVLPTR", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9UHL9-1", "uniprot_id": "GT2D1_HUMAN", "id": "Q9UHL9-1", "name": "General transcription factor II-I repeat domain-containing protein 1", "aln": "MALLGKR-CDVPTNGCGPDRWNSAFTRKDEIITSLVSALDSMCSALSKLNAEVACVAVHDESAFVVGTEKGRMFLNARKELQSDFLRFCRGPPWKDPEAEHPK---------KVQRGEGGGRSLPRSSLEHGSDVYLLRKMVEEVFDVLYSEALGRASVVPLPYERLLREPGLLAVQGLPEGLAFRRPAEYDPKALMAILEHSHRIRFKLKRPLEDGGRDSKALVELNGVSLIPKGSRDCGLHGQAPKVPPQDLPPTATSSSMASFLYSTALPNHAIRELKQEAPSCPLAPSDLGLSRP-MPEPKATGAQDFSDCCGQ-KPTGPGGPLIQN---VHASKRILFSIVHDKSEKWDAFIKETEDINTLRECVQILFNSRYAEALGLDHMVPVPYRKIACDPEAVEIVGIPDKIPFKRPCTYGVPKLKRILEERHSIHFIIKRMFDERIFTGN-KFTKDTTKLEPASP----PEDTSAEVSRATVLDLAGNARSDKGSMS--EDCGPGTSGELGGLRPIKIEPEDLDIIQVTVPDPSPTSEEMTDSMPGHLPSEDSGYGMEMLTDKGLSEDARPEERPVEDSHGDVIRPLRKQVELLFNTRYAKAIGISEPVKVPYSKFLMHPEELFVVGLPEGISLRRPNCFGIAKLRKILEASNSIQFVIKRPELLTEGVKEPIMDSQGTASSLGFSPPALPPERDSGDPLVDESL--KRQGFQENYDARLSRIDIANTLREQVQDLFNKKYGEALGIKYPVQVPYKRIKSNPGSVIIEGLPPGIPFRKPCTFGSQNLERILAVADKIKFTVTRPFQGLIPKP---------------------------DEDDANRLGEKVILREQVKELFNEKYGEALGLNRPVLVPYKLIRDSPDAVEVTGLPDDIPFRNPNTYDIHRLEKILKAREHVRMVIINQLQPFAEICNDA-------------------------------------------------------------------------------------------------------KVPAKDSSIPKRKRKRVSEGNSVSSSSSSSSSSSSNPDSVASANQISLVQ------------WPMYMVDY-------AGLNVQLPGPLNY-------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9PLI6-1", "uniprot_id": "A0A8M9PLI6_DANRE", "id": "A0A8M9PLI6-1", "name": "", "aln": "MAQIRKLGCDGMRTNSRPELKVPQVSARQEILTSLVSALDSVCSAMSKLNAEVACVTVHEDSVIAVGTEKGRIFLNSRKEIQTDFHKFCKVSCLQALNSMNSHSKVPEVDCSRTGKDSSGQQGRQRALTDTHSNIFVLRKMVEEVFSVLYSEAVGKSSLVPVPYDWILKDPSSVVVYGLPDGVTLRKPSEYDTKTLMKILEQSNRIRFIVKRTPEEPSRDAKSCPEVNHHSSTSKSAS------NHTSVKPSVQEVSASNSMLSSFLYGMPMSSQPHPDSKLDLKPTSLHS--IGKERPGMWTPAEEKAVQAKECADNGERIGLAADLTQSPPSIHVSKRLLFSIVHEKSEKWDSFIRETEDINTLRECVQILFNSRYAEALGLDHMVPVPYRKIACDPEAVEIIGIPDKIPFKRPCTYGVPKLKRILEERHAVRFVVRRMFDERIFTAAGKVAKEEGKQDGPASEDGFPEGLRIPSSSLELVSNTHSSRSTSSCVSPLAECEAGPSGDCLPLKKIKTEPPDGEIIQVTVPESSASTEESSEPQAERVTPDLCRPKEPVAEDLTPKSTPQGLKRAVEEDIGEMILQLRKQVESLFSCKYSEALGLPEPAKVPYSKFQMYPDDLYVTGLPEGMTFRRPNCFGAAKLRKILSASSQITFVITRPELLTEPVKNESVSKTTSES----------AETDSKDQSDDPGPASKRPGFSDSLEAKLSRIDLANTLREQVQDLFNRKYGEALGIKYPVQVPYKRIKSNPGSVIIEGLPPGIPFRKPCTFGSQNLERILAVADKISFSITRPFQGLIPKPAPRRITILKKG-----------YTPISEEDEVNRMGEKVILREQVKELFNKKYGEALGLDRSVIVPYKLIRANPGSLEVCGLPDDIPFRNPNTYDIVRLEKVLQAQDEITFNIKTPLQPFTELCTQS------------------------------------------------------------------------------------------------------CNKEGKEVSTNRRKRKRVLE--------SSQTSMPTAGDSALSTNQIPVMQ------------WPMYMVDY-------SGVNVQVPGKVKY-------------", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "** : * ** ... .: . .: ::*::.********:***:****:*****:**::*.:.:******:***:***:*:** :**: . : :: :.: :. : ..* :. *: : *::::*:*******.******:*::::**:**: :*::*. :.* ***:*:::*:*:***.*:** ***:*:**** ::*. :: .:*:*: *:* * .*.: : ..* *. :*: * ::.***. .:..:. : * : . .* . :* * : * : : .:*..: * .. * *. :*.***:******:******.**:* ********************************************:***************************:::*:::*********. *.:*: * : .:. **. . ::. : .: * ..:* :* .*.**: *: ** ** : :******.:.*.::** ::. . ::..: . : * .. . :*..*:. *::* ****** **. :*::*:* .**.******* *:*::*:* *****:::******* *******.**..* ***.******: **: :.. * ** * * ** *:.:. :::*****:*************:****************************************************:*****.*::*********** :**:.**:***************:********:*.*:******* .*.::** **************** ****:*:*::.: : * . ****:*:*.:. : .*: :****** * **.:* . :*. *:***.:: **: : :* : : * ", "identical_positions": 484, "similar_positions": 266, "identity": "42.27%" }, { "cls_id": "homologset.agr.MGI:1862037", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q63633-1", "uniprot_id": "S12A5_RAT", "id": "Q63633-1", "name": "Solute carrier family 12 member 5", "aln": "MSRRFTVTSLPPAASAASADPESRRHSVADPRRLPREDVKGDGNPKESSPFINS--TDTEKGREYDGRNMALFEEEMDTSPMVSSLLSGLANYTNLPQGSKEHEEAENNEGGKKKPVQAPRMGTFMGVYLPCLQNIFGVILFLRLTWVVGIAGIMESFCMVFICCSCTMLTAISMSAIATNGVVPAGGSYYMISRSLGPEFGGAVGLCFYLGTTFAGAMYILGTIEILLAYLFPAMAIFKAEDASG--EAAAMLNNMRVYGTCVLTCMATVVFVGVKYVNKFALVFLGCVILSILAIYAGVIKSAFDPPNFPICLLGNRTLSRHGFDVCAKLAWEGNETVTTRLWGLFCSSRLLNATCDEYFTRNNVTEIQGIPGAASGLIKENLWSSYLTKGVIVERRGMPSVGLADGTPVDMDHPYVFSDMTSYFTLLVGIYFPSVTGIMAGSNRSGDLRDAQKSIPTGTILAIATTSAVYISSVVLFGACIEGVVLRDKFGEAVNGNLVVGTLAWPSPWVIVIGSFFSTCGAGLQSLTGAPRLLQAISRDGIVPFLQVFGHGKANGEPTWALLLTACICEIGILIASLDEVAPILSMFFLMCYMFVNLACAVQTLLRTPNWRPRFRYYHWTLSFLGMSLCLALMFICSWYYALVAMLIAGLIYKYIEYRGAEKEWGDGIRGLSLSAARYALLRLEEGPPHTKNWRPQLLVLVRVDQDQNVVHPQLLSLTSQLKAGKGLTIVGSVLEGTFLDNHPQAQRAEESIRRLMEAEKVKGFCQVVISSNLRDGVSHLIQSGGLGGLQHNTVLVGWPRNWRQKEDHQTWRNFIELVRETTAGHLALLVTKNVSMFPGNPERFSEGSIDVWWIVHDGGMLMLLPFLLRHHKVWRKCKMRIFTVAQMDDNSIQMKKDLTTFLYHLRITAEVEVVEMHESDISAYTYEKTLVMEQRSQILKQMHLTKNEREREIQSITDESRGSIRRKNPANTRLRLNVPEETACDN-EEKPEEE---------VQLIHDQSAPSCPSSSPSPGEEPEGEGETDPEKVHLTWTKDKSAAQKNKGPSPVSSEGIKDFFSMKPEWENLNQSNVRRMHTAVRLNEVIVNKSRDAKLVLLNMPGPPRNRNGDE--NYMEFLEVLTEQLDRVMLVRGGGREVITIYS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q91V14-1", "uniprot_id": "S12A5_MOUSE", "id": "Q91V14-1", "name": "Solute carrier family 12 member 5", "aln": "MSRRFTVTSLPPAASAASADPESRRHSVADPRRLPREDVKGDGNPKESSPFINS--TDTEKGREYDGRNMALFEEEMDTSPMVSSLLSGLANYTNLPQGSREHEEAENNEGGKKKPVQAPRMGTFMGVYLPCLQNIFGVILFLRLTWVVGIAGIMESFCMVFICCSCTMLTAISMSAIATNGVVPAGGSYYMISRSLGPEFGGAVGLCFYLGTTFAGAMYILGTIEILLAYLFPAMAIFKAEDASG--EAAAMLNNMRVYGTCVLTCMATVVFVGVKYVNKFALVFLGCVILSILAIYAGVIKSAFDPPNFPICLLGNRTLSRHGFDVCAKLAWEGNETVTTRLWGLFCSSRLLNATCDEYFTRNNVTEIQGIPGAASGLIKENLWSSYLTKGVIVERRGMPSVGLADGTPVDMDHPYVFSDMTSYFTLLVGIYFPSVTGIMAGSNRSGDLRDAQKSIPTGTILAIATTSAVYISSVVLFGACIEGVVLRDKFGEAVNGNLVVGTLAWPSPWVIVIGSFFSTCGAGLQSLTGAPRLLQAISRDGIVPFLQVFGHGKANGEPTWALLLTACICEIGILIASLDEVAPILSMFFLMCYMFVNLACAVQTLLRTPNWRPRFRYYHWTLSFLGMSLCLALMFICSWYYALVAMLIAGLIYKYIEYRGAEKEWGDGIRGLSLSAARYALLRLEEGPPHTKNWRPQLLVLVRVDQDQNVVHPQLLSLTSQLKAGKGLTIVGSVLEGTFLDNHPQAQRAEESIRRLMEAEKVKGFCQVVISSNLRDGVSHLIQSGGLGGLQHNTVLVGWPRNWRQKEDHQTWRNFIELVRETTAGHLALLVTKNVSMFPGNPERFSEGSIDVWWIVHDGGMLMLLPFLLRHHKVWRKCKMRIFTVAQMDDNSIQMKKDLTTFLYHLRITAEVEVVEMHESDISAYTYEKTLVMEQRSQILKQMHLTKNEREREIQSITDESRGSIRRKNPANPRLRLNVPEETACDN-EEKPEEE---------VQLIHDQSAPSCPSSSPSPGEEPEGERETDP-EVHLTWTKDKSVAEKNKGPSPVSSEGIKDFFSMKPEWENLNQSNVRRMHTAVRLNEVIVNKSRDAKLVLLNMPGPPRNRNGDE--NYMEFLEVLTEQLDRVMLVRGGGREVITIYS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9H2X9-1", "uniprot_id": "S12A5_HUMAN", "id": "Q9H2X9-1", "name": "Solute carrier family 12 member 5", "aln": "MSRRFTVTSLPPAGPARSPDPESRRHSVADPRHLPGEDVKGDGNPKESSPFINS--TDTEKGKEYDGKNMALFEEEMDTSPMVSSLLSGLANYTNLPQGSREHEEAENNEGGKKKPVQAPRMGTFMGVYLPCLQNIFGVILFLRLTWVVGIAGIMESFCMVFICCSCTMLTAISMSAIATNGVVPAGGSYYMISRSLGPEFGGAVGLCFYLGTTFAGAMYILGTIEILLAYLFPAMAIFKAEDASG--EAAAMLNNMRVYGTCVLTCMATVVFVGVKYVNKFALVFLGCVILSILAIYAGVIKSAFDPPNFPICLLGNRTLSRHGFDVCAKLAWEGNETVTTRLWGLFCSSRFLNATCDEYFTRNNVTEIQGIPGAASGLIKENLWSSYLTKGVIVERSGMTSVGLADGTPIDMDHPYVFSDMTSYFTLLVGIYFPSVTGIMAGSNRSGDLRDAQKSIPTGTILAIATTSAVYISSVVLFGACIEGVVLRDKFGEAVNGNLVVGTLAWPSPWVIVIGSFFSTCGAGLQSLTGAPRLLQAISRDGIVPFLQVFGHGKANGEPTWALLLTACICEIGILIASLDEVAPILSMFFLMCYMFVNLACAVQTLLRTPNWRPRFRYYHWTLSFLGMSLCLALMFICSWYYALVAMLIAGLIYKYIEYRGAEKEWGDGIRGLSLSAARYALLRLEEGPPHTKNWRPQLLVLVRVDQDQNVVHPQLLSLTSQLKAGKGLTIVGSVLEGTFLENHPQAQRAEESIRRLMEAEKVKGFCQVVISSNLRDGVSHLIQSGGLGGLQHNTVLVGWPRNWRQKEDHQTWRNFIELVRETTAGHLALLVTKNVSMFPGNPERFSEGSIDVWWIVHDGGMLMLLPFLLRHHKVWRKCKMRIFTVAQMDDNSIQMKKDLTTFLYHLRITAEVEVVEMHESDISAYTYEKTLVMEQRSQILKQMHLTKNEREREIQSITDESRGSIRRKNPANTRLRLNVPEETAGDS-EEKPEEE---------VQLIHDQSAPSCPSSSPSPGEEPEGEGETDPEKVHLTWTKDKSVAEKNKGPSPVSSEGIKDFFSMKPEWENLNQSNVRRMHTAVRLNEVIVKKSRDAKLVLLNMPGPPRNRNGDE--NYMEFLEVLTEHLDRVMLVRGGGREVITIYS", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AC58JWE2-1", "uniprot_id": "A0AC58JWE2_DANRE", "id": "A0AC58JWE2-1", "name": "", "aln": "MSQRFTVTTGDIQGEVN--QLFEGDEETPSTAAAAGGSGKGDGNPKESSPFINS--TDPEKNQQFDGKNMALFEDEMDTIPMVSSLLSSLANYSNLPQGSKEHEEAENNEGSRKKPVQAPRMGTLMGVYLPCLQNILGVILFLRMTWMVGIGGVIEAFIIVLMCCSTTMLTAISMSAIATNGVVPAGGSYYMISRSLGPEFGGAVGICFYLGTTYAGAMYILGCIEILLVYIVPQAAIFKMEGLEGAEAEAAMLNNMRVYGTLVLSFMAIVVFVGVKYVNKLALVFLACVICSILAVYAGVIKTAFEPPVFPVCVLGNRTLVWKGFDVCAKVIERENATVTTKLWRLFCDSEFLNATCDTYFTNNNVTEMQGIPGVMSGTLRENLFGNYMDKGAFIEKTGLSSVVEPDSIPTNTNR-YVLADITSFFTMLVGIYFPSVTGIMAGSNRSGDLRDAQKSIPIGTILAITTTSIIYMSSVVLFGACIEGTVLRDKFGEAVRGNLVIGTLAWPSPWVIVIGSFFSTCGAGLQSLTGAPRLMQAIARDGIVPFLRVFGHGKANGEPTWALLLTACICESGILIASLDNVAPILSMFFLMCYMFVNLACAVQTLLRTPNWRPRFKFYHWTLSFLGMSLCLSLMFICSWYYAIVAMGIAGCIYKYIEFRGAEKEWGDGIRGLSLSAARFALMRLEEGPPHTKNWRPQILVLVNMDGELKVDQPRMLSLTSQLKAGKGLTIVGTALEGTYLENHDQGQQAEQSLRKLMETEKVKGFSQVVISSNMRDAMSHLVQASGLGGLQHNTVLASWPRNWKQAEDHQSWRNFIELVRETTAGSKALLVPKNISAFPSNGERFTEGHIDVWWIVHDGGMLMLLPFLLRQHKVWRKCKMRIFTVAQMDDNSIQMKKDLTTFLYHLRIDAAVEVVEMHDSDISAYTYEKTLMMEQRSQILKQINLTKTEREREIQSITDSSRGSIRRKNPAAVTTQLSVTEEPAASSKEQKPEEECVPVSPSQQEQLIHDKSTN--PPTPATP-QSPSADAQTPGTAVQMTWSEVKCDGEQNKPVGATTPEAIKDLFNMKPEWENLNQSNVRRMHTALRLNEVIIKKSQEAKLVLLNMPGPPRNRSGDE--NYMEFMEVLTEGLNRVLLVRGGGREVITIYS", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8M3B534-1", "uniprot_id": "A0A8M3B534_DANRE", "id": "A0A8M3B534-1", "name": "", "aln": "-----------MMNNLN--ECEEGD---------GGPNSQGDATSKESSPFINSSTSDVEKSQQYDGKNMALFEEEMDTSPMVSSLLSSLANYSNLTQGSKEHEEAENNEEARKKAAQAPRMGTIMGVYLPCLQNILGVILFLRMTWLVGVGGVLGTFTIVFMCCSTTMLTAISMSAIATNGVVPAGGSYYMISRSLGPEFGGAVGICFFLGTTFAGAMYILGCIEILLIYIVPSAAIFKMEGLEGSEAEAALLNNMRVYGTIVLTFMAIVVFVGVKYVNKLALVFLACVILSILAIYAGVIKTSFDPPDFPVCVLGNRTLVSKAYDICAKTIERGNATITTKLWRSFCDSEFLNATCDEYFVNNNISQIQGIPGVTSGILAENLFSGYMEKNSVLEKRGLQAVQDPELPVTNSNR-YVLADITSFFTLLVGIYFPSVTGIMAGSNRSGDLQDAQKSIPVGTILAITTTSIIYMSSVILFGACVDGVVLRDKFGEGVSGNLVIGTLAWPSPWVIVFGSFFSTCGAGLQSLTGAPRLLQAIARDGIIPFLRVFGHGKANGEPTWALLLTACICESGILIASLDAVAPILSMFFLMCYMFVNLACALQTLLRTPNWRPRFKFYHWALSLLGMSLCLTLMFLCSWYYAIVAMVIAGCIYKYIEFCGAEKEWGDGIRGISLSAARFALMRLEEGPPHTKNWRPQILVLTTLDGEQNVEQPRLLSLTSQLKAGKGLTIVGACIEGTYLNNQPKTQKADQSLRKLMEVEKVKGFSQVVISSNLRDATSHLIQAGGLGGLRHNTVLVSFPKNWKQAEEHHRCRNFIEVVRETTAGHMALLVPKNISAYPSNGERFTEGHIDVWWIVHDGGMLMLLPFLLRQHKVWRKCKMRIFTVAQMDDNSIQMKKDLMTFLYHLRLDAAVEVVEMLDNDISAYTYEKTLMMEQRSQILKEMHLTKNEREREIQSITDVSRGSIRRKNPSNLHPQRSIAEESVAGSGEEKPEEESVRVSHPRQVQLIQGKNATPTPTSPTSP-TAPTPATMSPGEEIQMTWTD---DTEKANNPAVANPENIKDMFNMKPEWENLNQSNVRRMHHAQKLNEVIVKKSQEAKLVLLNMPGPPRNRTGEE--NYMEFLEVLTEGLNRVLLVRGGGREVITIYS", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A0B4LGD3-1", "uniprot_id": "A0A0B4LGD3_DROME", "id": "A0A0B4LGD3-1", "name": "", "aln": "-----------MQSNSAKDDSDEMEIIP------SEHNGTVHETKNEDSGDIHR---AEENQKSSIDPNLYLYDDDLETRPHISTFISSIANYENTIPAAT--------DPDAKPAAPSARMGTLIGVFLPCIQNIFGVILFIRLTWVVGTAGAVCGFLIVLTCCCVTMLTAISMSAIATNGVVPAGGSYFMISRSLGPEFGGAVGMLFYTGTTLAAAMYIVGAVEIVLTYMAPWASIFGDFTKDA----DAMYNNFRVYGTLLLIFMGLIVFLGVKFVNKFATVALACVILSIIAVYVGIFDNIHGNEKLYMCVLGKRLLKDIPLENCTKED--------SFLRDIYCP----DGKCEEYYLANNVTKVKGIKGLASGVFYDNIFPSFLEKGQFIS-YGKSAIDIENTSGESYNQ--IMADITTSFTLLIGIFFPSVTGIMAGSNRSGDLADAQKSIPIGTICAILTTSTVYLSSVMFFAGTVDNLLLRDKFGQSIGGKLVVANIAWPNQWVILIGSFLSTLGAGLQSLTGAPRLLQAIARDEIIPFLAPFAKSSKRGEPTRALLLTIVICQCGILLGNVDLLAPLLSMFFLMCYGFVNLACAVQTLLRTPNWRPRFKFYHWSLSLIGLTLCISVMIMTSWYFALIAMGMAIIIYKYIEYRGAEKEWGDGIRGMALTAARYSLLRLEEGPPHTKNWRPQILVLSKLNDNLLPKYRKIFSFATQLKAGKGLTICVSVIKGDHTKITNKAVDAKATLRKYMTDEKVKGFCDVLVAQQIGEGLSSVIQTIGLGGMKPNTVIIGWPYSWRQ-EGRNSWKTFIQTVRTVAACHMALMVPKGINFYPESNHKIG-GNIDIWWIVHDGGLLMLLPFLLKQHRTWRNCKLRIFTVAQIEDNSIQMKKDLKTFLYHLRIEADVEVVEMNNSDISAYTYERTLMMEQRNQMLRALGLNKKENSKVVQTIMD------YKETPSDNK--MSLVQTIVDHHYDATKTAS---------------KVRFADPTIEETQHHDSQNDEKRNSIDLDGPENADTPETTSNKDESTEKADG-----DFKSSVK-PDEFNVRRMHTAIKLNEVIVEKSQDAQLVIMNLPGPPREVRAERERNYMEFLEVLTEGLEKVLMVRGGGREVITIYS", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . . . . :*.* *: *: :. . *: *::::::* * :*:::*.:*** * .: : * .. :.****::**:***:***:*****:*:**:** .* : * :*: **. ***********************:***************: *: *** *.****:* :**:* *: * :** .. *: **:***** :* *. :**:***:***:* * *.*** **:*:*.*::.. . : :*:**:* * : *:* : * :* :..*: *: **:::::** * ** : :*:: .:: *. .:. * :: : . :: :::*:*: **:*:**:***************** ******* *** ** *** :*:***::*.. ::. :******:.: *:**:..:***. ***::***:** *************:***:** *:*** *.:.. .**** ***** **: ***:..:* :**:********* *******:*************::***:**::*::**:::*:: ***:*::** :* ******: ************::*:***::*:***************:*** :: : :::*:::********** : ::* . . : *. ::*: * ******.:*:::.:: :. * ::*: ****:: ***: .:* .*:* * :: :.**: ** .:* **:*.*.:. :* . .:: * **:********:********::*:.**:**:*******::********** *******: * ****** :.********:**:****.*:*: : *.*.*..: :*:* * ::.*: .: : . : . . : *. : . :. . . . : . ..: .:*.. : :: ****** * :*****::**::*:**::*:*****: .:. *****:***** *::*::*************", "identical_positions": 510, "similar_positions": 310, "identity": "44.16%" }, { "cls_id": "homologset.agr.MGI:1888388", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P0C0S5-1", "uniprot_id": "H2AZ_HUMAN", "id": "P0C0S5-1", "name": "Histone H2A.Z", "aln": "MAG---GKAGKDSGK--AKTKAVSRSQRAGLQFPVGRIHRHLKSRTTSHGRVGATAAVYSAAILEYLTAEVLELAGNASKDLKVKRITPRHLQLAIRGDEELDSLIKATIAGGGVIPHIHKSLIGKKG------QQK-TV------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P0C0S7-1", "uniprot_id": "H2AZ_RAT", "id": "P0C0S7-1", "name": "Histone H2A.Z", "aln": "MAG---GKAGKDSGK--AKTKAVSRSQRAGLQFPVGRIHRHLKSRTTSHGRVGATAAVYSAAILEYLTAEVLELAGNASKDLKVKRITPRHLQLAIRGDEELDSLIKATIAGGGVIPHIHKSLIGKKG------QQK-TV------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P0C0S6-1", "uniprot_id": "H2AZ_MOUSE", "id": "P0C0S6-1", "name": "Histone H2A.Z", "aln": "MAG---GKAGKDSGK--AKTKAVSRSQRAGLQFPVGRIHRHLKSRTTSHGRVGATAAVYSAAILEYLTAEVLELAGNASKDLKVKRITPRHLQLAIRGDEELDSLIKATIAGGGVIPHIHKSLIGKKG------QQK-TV------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P08985-1", "uniprot_id": "H2AV_DROME", "id": "P08985-1", "name": "Histone H2A.v", "aln": "MAG---GKAGKDSGK--AKAKAVSRSARAGLQFPVGRIHRHLKSRTTSHGRVGATAAVYSAAILEYLTAEVLELAGNASKDLKVKRITPRHLQLAIRGDEELDSLIKATIAGGGVIPHIHKSLIGKKEETVQDPQRKGNVILSQAY", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q12692-1", "uniprot_id": "H2AZ_YEAST", "id": "Q12692-1", "name": "Histone H2A.Z", "aln": "MSGKAHGGKGKSGAKDSGSLRSQSSSARAGLQFPVGRIKRYLKRHATGRTRVGSKAAIYLTAVLEYLTAEVLELAGNAAKDLKVKRITPRHLQLAIRGDDELDSLIRATIASGGVLPHINKALLLKVE-------KKGSKK-----", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*:* * **...* .. :: * * ***********:*:** ::*.: ***:.**:* :*:***************:********************:******:****.***:***:*:*: * :* . ", "identical_positions": 85, "similar_positions": 29, "identity": "58.22%" }, { "cls_id": "homologset.agr.MGI:1888480", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q63317-1", "uniprot_id": "LY6B_RAT", "id": "Q63317-1", "name": "Lymphocyte antigen 6B", "aln": "-----------------------------MNRSCAMKSCVLILLLALLCAERAQGLNCYNCTMIPFGNTCSSTATCPYPDGVCTIQVAEVVVSSVRLKVKSNLCLPGCPKSPQTPEVLGTVVHVNTDCCNTDLCNAAGPTGGSTWTMAGVLLFILGSVLLQTLL----------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0A8I6A377-1", "uniprot_id": "A0A8I6A377_RAT", "id": "A0A8I6A377-1", "name": "", "aln": "-----------------------------MNSSCAIKSCVLILLLPLLCAERAQGLNCYNCTMIPFGNTCSSTATCSYPDGVCAIQVAEVVMGSVRLKVKDHICLPVCPTSSQTAEILGTVVDMKISCCNTDLCNAAGPTGGSTWTMARVLLFSLGSVLLQILLEGSSKAPPPLSFYPYV", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q63318-1", "uniprot_id": "Q63318_RAT", "id": "Q63318-1", "name": "", "aln": "-----------------------------MNRSCAMKSYVLILLLPLLCAERAQGLKCYSCIEVPLNANCS-TATCPYSDGVCVSQVLEAVEGSVRRTAKSNLCLPICPKFPQRTEILGTVVYTKVSCCNTDLCNAAGPTGGSTWTVAGVLLFSLGSVLLETLL----------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0A8I6A001-1", "uniprot_id": "A0A8I6A001_RAT", "id": "A0A8I6A001-1", "name": "", "aln": "MNWQMRPGRHFMAWILCVFLFSLCTPSQRMNSSCAMKSCVLIFFLALLCAERAQGLTCYNCIAVPLNTTCS-TATCPYSDGVCVSQVVEAVKDSVKGKAKSNLCLPGCPKFPQRTEILGTVVYTKISCCNTDFCNAAGPTGGSTWTMAGVLLFSLGSVLLQTLL----------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9WU67-1", "uniprot_id": "LY6I_MOUSE", "id": "Q9WU67-1", "name": "Lymphocyte antigen 6I", "aln": "-----------------------------MDTSHAIKSCVLILLVTLLCAERAQGLECYQCYGVPFETSCP-SFTCPYPDGFCVAQEEEFIANSQRKKVKSRSCHPFCPDEIEKKFILDPNTKMNISCCQEDLCNAAVPTGGSSWTTAGVLLFSLGSVLLQTLM----------------", "tax_id": 10090, "tax_name": "Mouse" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *: * *:** ***:::.********** **.* :*: .*. : **.*.**.*. * * : .* : ..*.. * * ** : :*.. . : .**: *:**** *****:** * **** ******: *: ", "identical_positions": 64, "similar_positions": 35, "identity": "35.56%" }, { "cls_id": "homologset.agr.MGI:1888495", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "F1LN08-1", "uniprot_id": "F1LN08_RAT", "id": "F1LN08-1", "name": "Zinc finger protein 276", "aln": "MKRDRLGRFLSPGIARQRGSSGSSCGSGRTRGRPSRTGGSSADGAAPQLSWG-STRSCGDTGEDGTDEAGAGRTLTMGHCRLCHGKFSSRSLRSISERVPGETSERLSPGERVFIRDFQRLLGVAVHQDPALPQFVCKNCYTQFYQCHSLLRSFLQRVNVSPAGQRKP----CTKVGVQPPTVAEEGACMADLITSSPQCLHGLVGWVHEHAVNCGCLPSLQRTLSSEYCGVIQAVWGCDQGHDFTMDTDSGCRALLLDSALAVK--WGKELAPRLAQSSASDPTGAASQLCQAR--ETQVGSETKTLPSVDVALLHSHGDSVGPGLSPYIQPNLAPSEAPGQLGEKQVPSSTSDDRVKDEFSDLSEGDVLSEDDSDKKQTPQSSDESFEPYPEKKVSGKKSEGKEAKRPEEPKIRKKPGPKPGWKKKLRCEREELPTIYKCPYQGCTAVYRGADGMKKHIKEHHEEVRERPCPHPGCNKVFMIDRYLQRHVKLIHTEVRNYICDECGQTFKQRKHLLVHQMRHSGAKPLQCEVCGFQCRQRASLKYHMTKHKAETELDFACDQCGRRFEKAHNLNVHMSMVHPLTQTQ--ALPLEAEPPPGPLSLAGTVEGQAVKPEPT", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8CE64-1", "uniprot_id": "ZN276_MOUSE", "id": "Q8CE64-1", "name": "Zinc finger protein 276", "aln": "MKRDRLGRFLSPGIARQRGGSGGGCGSGRTRGRPSRSGGTSADGAAAQLSWGSMTRSCGDTGDDGTDEAGAGRTLAMGHCRLCHGKFSSRSLRSISDRVPGETSERLSPGERVFIRDFQRLLGVAVHQDPALPQSVCKNCYTQFYQCHSLLRTFLQRVNVSPAGQRKP----CTKVGVQPTTVAEEGACVADLIASSPRCLHGLVGWVHEHAVSCGSLPSLQRTLSSEYCGIIQAVWGCDQGHDFTMDTASSCRALFLDSALAVKWAWGKDLSPRLAQNSESNPTGAASRLCQAR--ETQVGSETKTLPSVDVALLHSHGDSVGPGLGPCTQPHLAPSEAPGQLGETQVPSSTSDDRVKDEFSDLSEGDFLSEDESDKKQTPQSSDESFEPYPEKKVSGKKSEGREAKRPEEPKIRKKPGPKPGWKKKLRCEREELPTIYKCPYQGCTAVYRGADGMKKHIKEHHEEVRERPCPHPGCNKVFMIDRYLQRHVKLIHTEVRNYICDECGQTFKQRKHLLVHQMRHSGAKPLQCEVCGFQCRQRASLKYHMTKHKAETELDFACDQCGRRFEKAHNLNVHMSMVHPLTQAQDRALPLEAEPPPGPLSPSGTMEGQAVKPEPT", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8N554-1", "uniprot_id": "ZN276_HUMAN", "id": "Q8N554-1", "name": "Zinc finger protein 276", "aln": "MKRDRLGRFLSPGSSRQCGASDGGGGVSRTRGRPSLSGGPRVDGATARRAWG-PVGSCGDAGEDGADEAGAGRALAMGHCRLCHGKFSSRSLRSISERAPGASMERPSAEERVLVRDFQRLLGVAVRQDPTLSPFVCKSCHAQFYQCHSLLKSFLQRVNASPAGRRKP----CAKVGAQPPTGAEEGACLVDLITSSPQCLHGLVGWVHGHAASCGALPHLQRTLSSEYCGVIQVVWGCDQGHDYTMDTSSSCKAFLLDSALAVKWPWDKETAPRLPQHRGWNP-GDAPQTSQGRGTGTPVGAETKTLPSTDVAQPPSDSDAVGPRSGFPPQPSLPLCRAPGQLGEKQLPSSTSDDRVKDEFSDLSEGDVLSEDENDKKQNAQSSDESFEPYPERKVSGKKSESKEAKKSEEPRIRKKPGPKPGWKKKLRCEREELPTIYKCPYQGCTAVYRGADGMKKHIKEHHEEVRERPCPHPGCNKVFMIDRYLQRHVKLIHTEVRNYICDECGQTFKQRKHLLVHQMRHSGAKPLQCEVCGFQCRQRASLKYHMTKHKAETELDFACDQCGRRFEKAHNLNVHMSMVHPLTQTQDKALPLEAEPPPGPPSPSVTTEGQAVKPEPT", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9PUR8-1", "uniprot_id": "A0A8M9PUR8_DANRE", "id": "A0A8M9PUR8-1", "name": "Zinc finger protein 276", "aln": "--------------MRRRG--------TRTSRRETR-------------------------------DHSSGRSSSS-FCRLCHGKFSRRRLLQAFAQLQGEACGGVYP---LFCADFQQLLGIRMERDPALSQFICTGCHAQFYRCHSILLQFRSRVNLTPPTAHSYNDAVSSRSGAEHSSSQEDISLIRSQMPWDRRCLLSLVSWAHGHAEGCSSCPGLQEVLEGPCGGALRAVWGCGDGHSYVMDSGAAA-----------------------STHTTEDHTDEHAQPTHQQ------GAALSGSDPLRSAEPQNHSDTHDTQCSEQTDASLTP--AP----------------AEDADSELSDRNMLSDEECEEQRKSGSSEDS-DPHTDKRSSKRK----ETKTPE-PKTRRKPGPKPGWKNSSKSEREELPTIYKCPHQGCTAVYRGADGMKKHIKEHHEEVRERPCPHPGCNKVFMIDRYLQRHVKLIHTEVRNYICDQCGQTFKQRKHLSVHQMRHSGAKPLQCEVCGFQCRQRASLKYHMTKHKAEADLEFACVICGKRFEKAHNLNVHMSMVHPLMQSAGATVPADP-----PLTHS-------------", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *: * ** * : : .:**: : .********* * * . : * : . :: ***:***: :.:**:*. :*..*::***:***:* * .*** :*. :. .:: *.: .: *: : : . :. . :** .**.*.* ** .*.. * **..*.. * ::.****.:**.:.**: :.. . : . .: : : *: . . * ...*: .. . :. *. ** .:* *:**: :.**::: ::::.. **::* :*:.::: * :* *:* .* *: *:*********:. :.************:*************************************************************:*********** *************************************::*:*** **:****************** *: ::* :. * : : ", "identical_positions": 246, "similar_positions": 135, "identity": "39.68%" }, { "cls_id": "homologset.agr.MGI:1888496", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A0G2KAH3-1", "uniprot_id": "A0A0G2KAH3_RAT", "id": "A0A0G2KAH3-1", "name": "T-box transcription factor TBX20", "aln": "---------------------------------------------------------------MEFTASPKPQLSSRANAFSIAALMSSG--GPKEKEAAENTIKPLEQF---------------VEKSSCAQP-----------------------------------------------------------LGELTSLDAHAEFGGGGGSSPSSSS--------------------------------LCTEP--LIPTTPIIP----SEEMAKIACSLETKELWDKFHELGTEMIITKSGRRMFPTIRVSFSG----VDPEAKYIVLMDIVPVDNKRYRYAYHRSSWLVAGKADPPLPARLYVHPDSPFTGEQLLKQMVSFEKVKLTNNELDQHGHIILNSMHKYQPRVHIIKK---KDHTASLLNLKSEEFRTFIFPETVFTAVTAYQNQLITKLKIDSNPFAKGFRDSSRLTDIERESVESLIQKHSYARSPIRTYG--------------EEDVLGEESQTTPNRGSAFTTSDNLSLSSWVSSSSSFP-----------------GFQHPQPLTALGTSTASIATPIPHPIQGS----LPPYSRLGMPLTPSAIASSMQGSGPTFPSFHMPRYHHYFQQGPYAAIQGLR----------HSSAVMTPFV", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9ES03-1", "uniprot_id": "TBX20_MOUSE", "id": "Q9ES03-1", "name": "T-box transcription factor TBX20", "aln": "---------------------------------------------------------------MEFTASPKPQLSSRANAFSIAALMSSG--GPKEKEAAENTIKPLEQF---------------VEKSSCAQP-----------------------------------------------------------LGELTSLDAHAEFGGGGGS-PSSSS--------------------------------LCTEP--LIPTTPIIP----SEEMAKIACSLETKELWDKFHELGTEMIITKSGRRMFPTIRVSFSG----VDPESKYIVLMDIVPVDNKRYRYAYHRSSWLVAGKADPPLPARLYVHPDSPFTGEQLLKQMVSFEKVKLTNNELDQHGHIILNSMHKYQPRVHIIKK---KDHTASLLNLKSEEFRTFIFPETVFTAVTAYQNQLITKLKIDSNPFAKGFRDSSRLTDIERESVESLIQKHSYARSPIRTYG--------------EEDVLGEESQTTQSRGSAFTTSDNLSLSSWVSSSSSFP-----------------GFQHPQPLTALGTSTASIATPIPHPIQGS----LPPYSRLGMPLTPSAIASSMQGSGPTFPSFHMPRYHHYFQQGPYAAIQGLR----------HSSAVMTPFV", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9UMR3-1", "uniprot_id": "TBX20_HUMAN", "id": "Q9UMR3-1", "name": "T-box transcription factor TBX20", "aln": "---------------------------------------------------------------MEFTASPKPQLSSRANAFSIAALMSSG--GSKEKEATENTIKPLEQF---------------VEKSSCAQP-----------------------------------------------------------LGELTSLDAHGEFGGGSGSSPSSSS--------------------------------LCTEP--LIPTTPIIP----SEEMAKIACSLETKELWDKFHELGTEMIITKSGRRMFPTIRVSFSG----VDPEAKYIVLMDIVPVDNKRYRYAYHRSSWLVAGKADPPLPARLYVHPDSPFTGEQLLKQMVSFEKVKLTNNELDQHGHIILNSMHKYQPRVHIIKK---KDHTASLLNLKSEEFRTFIFPETVFTAVTAYQNQLITKLKIDSNPFAKGFRDSSRLTDIERESVESLIQKHSYARSPIRTYGG-------------EEDVLGDESQTTPNRGSAFTTSDNLSLSSWVSSSSSFP-----------------GFQHPQSLTALGTSTASIATPIPHPIQGS----LPPYSRLGMPLTPSAIASSMQGSGPTFPSFHMPRYHHYFQQGPYAAIQGLR----------HSSAVMTPFV", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9I9K7-1", "uniprot_id": "TBX20_DANRE", "id": "Q9I9K7-1", "name": "T-box transcription factor TBX20", "aln": "---------------------------------------------------------------MEYTSSPKPQLSSRANAFSIAALMSSG--KTKDKESEENTIKPLEQF---------------VEKSSCHPN-----------------------------------------------------------LGDLPPLETHSDFSSGGGT-GSGAP--------------------------------LCTEP--LIPTTPGVP----SEEMAKISCSLETKELWDKFHELGTEMIITKSGRRMFPTIRVSFSG----VDPDAKYIVLMDIVPVDNKRYRYAYHRSSWLVAGKADPPLPARLYVHPDSPFTGEQLLKQMVSFEKVKLTNNELDQHGHIILNSMHKYQPRVHIIKK---KDHTASLLNLKSEEFRTFVFTETVFTAVTAYQNQLITRLKIDSNPFAKGFRDSSRLTDIERESVESLIHKHSYARSPIRTYAG-------------DEETLGEEGHSAHSRGSAFTASDNLSLSSWVTTTSGFS-----------------GFQHPQSLSAIGTSTASLASPLPHPIQGS----LPPYSRLGMPLTPSALASSMQATGPTFPSFHMPRYHHYFQQGPYAAIQGLR----------HSSTVMTPFV", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q94890-1", "uniprot_id": "H15_DROME", "id": "Q94890-1", "name": "T-box protein H15", "aln": "MLLSNQPANTKPQQTPSPSQTQNFKSKLQQQIVSAAAAAAANIANGSSHHHHHQNHHHHHPLNNHHNHNHNQHNISFATDFSIAAIMARGGNAPSSREPSERSLSPASVERYSGQDADDDVDVDVVDCSDSEMPSATAAAAAAATTAAAAAAALQAQQQARQALRVAQQQQQQQQQQRQQTHHHATTGKQQRQHHNHHSSNTNNSSNSGNSNTNSKSSSQRGRSAAAVGAAATPSPPPPPPSQSPEELERLSPEESPAQQPTPKIVGSCNCDDLTPVQCHLETKELWDKFHELGTEMIITKSGRRMFPTVRVSFSGPLRQIQPADRYAVLLDVVPLDSRRYRYAYHRSSWLVAGKADPPPPSRIYAHPDCPLSPEALRKQVVSFEKVKLTNNEMDKSGQVVLNSMHRYQPRIHLVRLSHGQSIPGSPKELQDMDHKTFVFPETVFTAVTAYQNQLITKLKIDSNPFAKGFRDSSRLSDFDRDPMDAFFFDQHMRTAPLRFFPDPLMSQLTPQEADAASMALLEKARQHLQMFG-RSPYTEMLLPHLYQRSAAPP-PPPPAPHLSAFQLGMWQQQWPQLTAGFLASANQQAALALAAAGAN---RTPPPSMAVAPPAPATPTSSCGSASPDLRARPQLN-HYPQRFSPYQVPQHQ-------ASPPASNRAESP--", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VMR2-1", "uniprot_id": "Q9VMR2_DROME", "id": "Q9VMR2-1", "name": "", "aln": "MLVGSHPYLCN----------------------GVPAAPAAPNASG------------------QTTTTASKSAAGSATDFSIAAIMAR--EDASSRESSIRSASPISVE--------DEVDVDVVDCSDAEEP-------------------------PTKARRLNHHQHHQHHQHHHNNNNNNNN--NNVAHKSRNSGGAVAQTASAESQLNTSSTSSQGR---------CSTPPQSPGTEDSE--ERLTPEP---VQKAPKIVGSCNCDDLKPVQCHLETKELWDRFHDLGTEMIITKTGRRMFPTVRVSFSGPLRQIQPADRYAVLMDIIPMDSKRYRYAYHRSAWLVAGKADPAPPARLYAHPDSPFSCEALRKQVISFEKVKLTNNEMDKNGQIVLNSMHRYQPRIHLVRLSHGQSIPSNPKELQDLDHKTYVFPETVFTAVTAYQNQLITKLKIDSNPFAKGFRDSSRLTDFDRDPMEALLLEQQLR-SPLRLFPDPLMQQFAAQ-GDPSSMALFEKARQHLQMFGGNSPYAQLMMPQMYQAAAAAAGPPPPPPGLGAFH--MFQQQWPQLTAGFLASANQQAAAAQAAAQAQAQAQAAAAAMAANRTPPPPPTASTPSSTSSGSPSPDMRPRQYQRFSPYQLPGGQGPPSSAAGSPPAVNASRSPAH", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . . . . . *. *****:*: ...:*. .: .* . *: *.. . . : . .. . : :. * .* :* : .::: : * ********:**:*********:*******:****** ::* :* **:*::*:*.:*********:*********. *:*:*.***.*:: * * **::***********:*: *:::*****:****:*::: :. ... :*:. :.:*::*.****************:******************:*::*:.::::: .: :*:* : . .* ::.: . . :. :: :. ::. . * ** :.: :*: . *: . .. .. : .*.. ::* .: . . . : : .** . :* ", "identical_positions": 158, "similar_positions": 147, "identity": "23.41%" }, { "cls_id": "homologset.agr.MGI:1888498", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I6GHR1-1", "uniprot_id": "A0A8I6GHR1_RAT", "id": "A0A8I6GHR1-1", "name": "Gamma-aminobutyric acid receptor subunit theta", "aln": "MGIRGMLRAAALLLLIRTWLAESNDPSPTPKFHFELSSSMPEVILDLFNCKNCANEAVVQKILDRVLSTYDVRLRPNFGGAPVPVSISIYVSSIEQISEINMDYTITMFLHQTWKDTRLAY-----YETNLN-------LTLDYRMHEKLWVPDCYFVNSKDAFVHDVTAENRVFQLHPDGTVQYGIRLTTTAACSLDLQKFPMDKQSCKLEVESYGYTVEDIVLSWEDD-NAIHITDELHIPQYTYLGRTITSKEVYFYTGSYMRLIVKFQVQREVRSYLVQVYWPTVLTTILSWISFWMNYGSSAARVTIGLTSILVLTTIDSHMRDKLPHISCIKAIDIYILVCLFFVFLSLLEYVYINYLFFSQAPRRNHRRCRKPRRVVARYRYQEVVVANVQDGLINVEDRVEDRAGPLPDSPMQAHLASQESLGSLMFTSEEAQLATSESLSLLSSASSQVQLATGESLGDLPSTSEQTLPDYTIHFHGFLTNDSILPIKIRSHSDALGD------EDSEESLSSEESYGHGGSPTGRLKLQISQSA------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9JLF1-1", "uniprot_id": "GBRT_MOUSE", "id": "Q9JLF1-1", "name": "Gamma-aminobutyric acid receptor subunit theta", "aln": "MGIRGMLRAAALLLLIRTWLAESNGPSPTPKFHFELSSSTPEVILDLFNCKNCANEAVVQKILDRVLSTYDVRLRPNFGGAPVPVSVSIYVSSIEQISEINMDYTITMFLHQTWKDTRLAY-----YETNLN-------LTLDYRMHEKLWVPDCYFVNSKDAFVHDVTVENRVFQLHPDGTVRYGIRLTTTAACSLDLQKFPMDKQSCKLEVESYGYTVEDIVLSWEDD-NAIHITDGLHIPQYTYLGRTITSKEVYFYTGSYMRLIVKFQVQREVRSYLVQVYWPTVLTTILSWISFWMNYDSSAARVTIGLTSILVLTTIDSHMRDKLPHISCIKAIDIYILVCLFFVFLSLLEYVYINYLFFSQVPRRNHRRCRKPRRVVARYRYQEVVVANVQDGLINVEDRVEDRAGPLPDSPMQAHLASQESLGSLVFTSEQAQLATSESLSLLSSASSQTQLATGESLSDLPSTSEQTVPECTIHFHGFLTNDSIIPIKIHSRSDACDD------EDSEESLSSEESHGHGSSHTGRLKLQISQRCVQEASWDLDKIEILQDDISITSSWLGLDEQCKGDADSIWSLTDEELMACDQEKDSSSESEENCSPSPGCSFNEGFSFQLFKPNRVPKVDRWSRFLFPLSFGLFNVVYWLYHVY-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9UN88-1", "uniprot_id": "GBRT_HUMAN", "id": "Q9UN88-1", "name": "Gamma-aminobutyric acid receptor subunit theta", "aln": "MGIRGMLRAAVILLLIRTWLAEGNYPSPIPKFHFEFSSAVPEVVLNLFNCKNCANEAVVQKILDRVLSRYDVRLRPNFGGAPVPVRISIYVTSIEQISEMNMDYTITMFFHQTWKDSRLAY-----YETTLN-------LTLDYRMHEKLWVPDCYFLNSKDAFVHDVTVENRVFQLHPDGTVRYGIRLTTTAACSLDLHKFPMDKQACNLVVESYGYTVEDIILFWDDNGNAIHMTEELHIPQFTFLGRTITSKEVYFYTGSYIRLILKFQVQREVNSYLVQVYWPTVLTTITSWISFWMNYDSSAARVTIGLTSMLILTTIDSHLRDKLPNISCIKAIDIYILVCLFFVFLSLLEYVYINYLFYSRGPRRQPRRHRRPRRVIARYRYQQVVVGNVQDGLINVEDGVSS----LPITPAQAPLASPESLGSLTSTSEQAQLATSESLSPLTSLSGQAPLATGESLSDLPSTSEQARHSYGVRFNGFQADDSIIPTEIRNRVEAHGHGVTHDHEDSNESLSSDERHGHG--PSGKPMLHHGEKGVQEAGWDLD-------DNNDKSDCLAIKEQFKCDTNSTWGLNDDELMAHGQEKDSSSESEDSCPPSPGCSFTEGFSFDLFNPDYVPKVDKWSRFLFPLAFGLFNIVYWVYHMY-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q08832-1", "uniprot_id": "GBRB3_DROME", "id": "Q08832-1", "name": "Gamma-aminobutyric acid receptor subunit beta-like", "aln": "-----------MTCFTRVGVSCG--------LFFFLLGAQLQLIRCIRKDVLAGRLENVTQTISNILQGYDIRLRPNFGGEPLHVGMDLTIASFDAISEVNMDYTITMYLNQYWRDERLAFNIFGQYFDDENDDGISDVLTLSGDFAEKIWVPDTFFANDKNSFLHDVTERNKLVRLGGDGAVTYGMRFTTTLACMMDLHYYPLDSQNCTVEIESYGYTVSDVVMYWKPT--PVRGVEDAELPQFTIIGYETNDRKERLATGVYQRLSLSFKLQRNIGYFVFQTYLPSILIVMLSWVSFWINHEATSARVALGITTVLTMTTISTGVRSSLPRISYVKAIDIYLVMCFVFVFAALLEYAAVNYTYWGKRAKKKIKKVKECCPGKIGKSERSETCSTTED-IIELQD---------------VRMSPIPSLRRGTYNATLDSIGTETMNLGKFPPSFRITRNYGTGHSQLRRRAQRGISTRPRMLHALKRGASAIKATIPKIKD-----------------------------------------------------------------------------------------------------------------------------VNIIDKYSRMIFPISFLAFNLGYWLFYILE", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : *. :: . :.* : .: ::: : : ... * : :..:*. **:******** *: * :.: ::*:: ***:********:::* *:* ***: * * ***. : **:**** :* *.*::*:**** .*::.:* **:* **:*:*** ** :**: :*:*.* *.: :*******.*::: *. .:: .: .:**:* :* ..:: : ** * ** :.*::**:: ::.*.* *::* .: **:***:*: :::***::*:*::* :***.: :*..**.** :******:::*:.*** :****. :** ::.: .::: :: :. :. . ...:* :*:::* . ::. ** .: .:.*. . * : * . .:* ::: ::.: . * : * . : ", "identical_positions": 144, "similar_positions": 173, "identity": "21.88%" }, { "cls_id": "homologset.agr.MGI:1888499", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O55038-1", "uniprot_id": "CXL13_MOUSE", "id": "O55038-1", "name": "C-X-C motif chemokine 13", "aln": "MR-LSTATLLLLLASCLSPGHGILEAHYTNLKCRCSGVISTVVGLNIIDRIQVTPPGNGCPKTEVVIWTKMKKVICVNPRAKWLQRLLRHVQSKSLSSTPQAPVSKRRAA", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "F7F7W7-1", "uniprot_id": "F7F7W7_RAT", "id": "F7F7W7-1", "name": "", "aln": "MR-LCTAALLLLLAICLPPGHGILETHYTNLKCRCSKVSSTFINLILVDWIQVIRPGNGCPKTEIIFWTKAKKAICVNPTARWLPKVLKFVRSRSITSTPQAPVSKKRAA", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O43927-1", "uniprot_id": "CXL13_HUMAN", "id": "O43927-1", "name": "C-X-C motif chemokine 13", "aln": "MKFISTSLLLMLLVSSLSPVQGVLEVYYTSLRCRCVQESSVFIPRRFIDRIQILPRGNGCPRKEIIVWKKNKSIVCVDPQAEWIQRMMEVLRKRS-SSTLPVPVFKRKIP", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*: :.*: **:**. .*.* :*:**.:**.*:*** *..: ::* **: *****:.*::.*.* *. :**:* *.*: :::. ::.:* :** .** *:: .", "identical_positions": 41, "similar_positions": 44, "identity": "37.27%" }, { "cls_id": "homologset.agr.MGI:1888501", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q924U0-1", "uniprot_id": "LT4R2_RAT", "id": "Q924U0-1", "name": "Leukotriene B4 receptor 2", "aln": "-----------------------------------MSVCYRPPGNETLLSWKGSRATGTAFLLLAALLGLPGNGFVVWSLAGWRPTAGRPLAATLVLHLALADGAVLLLTPLFVAFLSRQAWPLGQVGCKAVYYVCALSMYASVLLTGLLSLQRCLAVTRPFLAPRLRSPALARRLLLGVWLAALVLAVPAAVYRHLWG------DRVCQLCHPSAVHAAAHLSLETLTAFVLPFGTVLGCYGVTLARLRGARWGSGRQGTRVGRLVSAIVLAFGLLWAPYHAVNLLQAVAALAPPE-GPLARLGGAGQAARAGTTALAFFSSSVNPVLYVFTAGDLLPRAGPRFLTRLFEGSGEARVG--SRSREGTMELRTTPRLKVVGQGRGYGDPGGG--GRMEKDSQEW---", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9JJL9-1", "uniprot_id": "LT4R2_MOUSE", "id": "Q9JJL9-1", "name": "Leukotriene B4 receptor 2", "aln": "-----------------------------------MSVCYRPPGNETLLSWKGSRATGTAFLLLAALLGLPGNGFVVWSLAGWRPTAGRPLAATLVLHLALADGAVLLLTPLFVAFLSQEAWPLGQVGCKAVYYVCALSMYASVLLTGLLSLQRCLAVTRPFLAPRLRSPALARRLLLGVWLAALVLAVPAAVYRHLWG------GRVCQLCHPSPVHAAAHLSLETLTAFVLPFGTVLGCYGVTLARLRGARWGSGRQGTRVGRLVSAIVLAFGLLWAPYHAVNLLQAVAALAPPE-GPLARLGGAGQAARAGTTALAFFSSSVNPVLYVFTAGDLLPRAGPRFLTRLFEGSGEARGG--SRSREGTMELRTTPKLKVMGQGRGNGDPGGGDGGKTEKDSQEW---", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9NPC1-1", "uniprot_id": "LT4R2_HUMAN", "id": "Q9NPC1-1", "name": "Leukotriene B4 receptor 2", "aln": "-----------------------------------MSVCYRPPGNETLLSWKTSRATGTAFLLLAALLGLPGNGFVVWSLAGWRPARGRPLAATLVLHLALADGAVLLLTPLFVAFLTRQAWPLGQAGCKAVYYVCALSMYASVLLTGLLSLQRCLAVTRPFLAPRLRSPALARRLLLAVWLAALLLAVPAAVYRHLWR------DRVCQLCHPSPVHAAAHLSLETLTAFVLPFGLMLGCYSVTLARLRGARWGSGRHGARVGRLVSAIVLAFGLLWAPYHAVNLLQAVAALAPPE-GALAKLGGAGQAARAGTTALAFFSSSVNPVLYVFTAGDLLPRAGPRFLTRLFEGSGEARGG--GRSREGTMELRTTPQLKVVGQGRGNGDPGGG----MEKDGPEWDL-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M6Z1F9-1", "uniprot_id": "A0A8M6Z1F9_DANRE", "id": "A0A8M6Z1F9-1", "name": "", "aln": "MALNLLSPSAFLEIAPSSIPMALQSPSFYTSTLHPTNLSNNTSGRGSIVDNKGGAITGAAILSLVFLLGVPGNVFIMWSILAR--ARRRSITTLLILNLAFADGFLMLLTPFFMVYLVQRSWVFSLALCKVLYYLCCANMYASIFMIMLMSLHRLVAIVWPKRVGAKTERKMLTRVLVGLWVLALGLSAPVLAFRNILSDSKKPEKFVCDCIHPETQYEVMQYSMETLLGFLLPYGVIIGSYTCILRRIRKTRFRR---RIRSEKLILVIVVTFGLFWLPYHIINMVQVTAALLPEGSAAKHRLQEIRANMRALTSTVAFVSSCINPVLYTFAGKSYIRREGLAFMARLFEGTALESTRKIRRSNQNSRERDKETDEGDSIKDKDSDSINTINANSVIKVAPQKNGK", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "E7F4K9-1", "uniprot_id": "E7F4K9_DANRE", "id": "E7F4K9-1", "name": "", "aln": "--------------------MALENGSFS-----MENITTASPKLKSVVDNSTSATFGALILSIAILLGIPGNLFIIWSILAR--ARKRSVTTLLILNLAFADGCLMFLTIFFIIYLAKQNWIFGEVLCKLLFYLCNTNMYASIMIITLMSLHRLVAVMWPSYLSVCTRRLTVLLVLGGLWVAVFLLAMPVLMFRAEKTIGNK--RIVCETHHNRTEQAVFQYTLETMVGFLVPYVIIVSSYVCILRRLRQTKFKR---MIRSENLIQAIIVTFCIFWLPYHILNVVQVMAALTPEGMPLKTQLKNIWESSRAVTSTLAFISSCANPVLYAFAGRSYIKADGLAFMARLFEGTVLDYS---ARKNQQTRD--------------------------VIRL-------", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .: .. :::. . . *: :* :. ***:*** *::**: . : *.::: *:*:**:*** :::** :*: :* :. * :. . ** ::*:* .****::: *:**:* :*: * :* .:*: .: *: *. :* **: * . . : ::**: .*::*: ::..* * *:* ::: * .*: .*:::* ::* *** :*::*. *** * :* ** *:::**.**. *****.*:. . : * *::*****: *..: : : : ", "identical_positions": 90, "similar_positions": 109, "identity": "22.11%" }, { "cls_id": "homologset.agr.MGI:1888504", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9EP95-1", "uniprot_id": "RETNA_MOUSE", "id": "Q9EP95-1", "name": "Resistin-like alpha", "aln": "MKTTTCSLLICISLLQLMVPVNTDETIEIIVENKVKELLANPANYPSTVTKTLSCTSVKTMNRWASCPAGMTATGCACGFACGSWEIQSGDTCNCLCLLVDWTTARCCQLS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q99P85-1", "uniprot_id": "RETNA_RAT", "id": "Q99P85-1", "name": "Resistin-like alpha", "aln": "MKTATCSLLICVFLLQLMVPVNTDGTLDIIGKKKVKELLAHQDNYPSAVRKTLSCTNVKSMSKWASCPAGMTATGCSCGFACGSWEIQNENICNCLCLIVDWAYARCCQLS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9BQ08-1", "uniprot_id": "RETNB_HUMAN", "id": "Q9BQ08-1", "name": "Resistin-like beta", "aln": "MGPSSCLLLILIPLLQLINPGSTQCSLDSVMDKKIKDVLNSLEYSPSPISKKLSCASVKSQGRPSSCPAGMAVTGCACGYGCGSWDVQLETTCHCQCSVVDWTTARCCHLT", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* .::* *** : ****: * .*: ::: : .:*:*::* **.: *.***:.**: .: :******:.***:**:.****::* *:* * :***: ****:*:", "identical_positions": 49, "similar_positions": 37, "identity": "44.14%" }, { "cls_id": "homologset.agr.MGI:1888505", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9BQ08-1", "uniprot_id": "RETNB_HUMAN", "id": "Q9BQ08-1", "name": "Resistin-like beta", "aln": "MGPSSCLLLILIPLLQLINPGSTQCSLDSVMDKKIKDVLNSLEYSPSPISKKLSCASVKSQGRPSSCPAGMAVTGCACGYGCGSWDVQLETTCHCQCSVVDWTTARCCHLT", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q99P86-1", "uniprot_id": "RETNB_MOUSE", "id": "Q99P86-1", "name": "Resistin-like beta", "aln": "MKPTLCFLFILVSLFPLIVPGNAQCSFESLVDQRIKEALSRQE------PKTISCTSVTSSGRLASCPAGMVVTGCACGYGCGSWDIRNGNTCHCQCSVMDWASARCCRMA", "tax_id": 10090, "tax_name": "Mouse" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* *: *:*:**:.*: ** **.:***::*::*::**:.*. * .*.:**:**.*.** :******.**************:: .********:**::****:::", "identical_positions": 62, "similar_positions": 34, "identity": "55.86%" }, { "cls_id": "homologset.agr.MGI:1888506", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8K4J7-1", "uniprot_id": "Q8K4J7_RAT", "id": "Q8K4J7-1", "name": "", "aln": "MKNLSFLLLFLFFLVLGLLGPSMSLCPMDEAISKKINQDFSSLLPAAMKNTVLHCWSVSSRGRLASCPEGTTVTSCSCGSGCGSWDVREDTMCHCQCGSIDWTAARCCTLRVGS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q99P87-1", "uniprot_id": "RETN_MOUSE", "id": "Q99P87-1", "name": "Resistin", "aln": "MKNLSFPLLFLFFLVPELLGSSMPLCPIDEAIDKKIKQDFNSLFPNAIKNIGLNCWTVSSRGKLASCPEGTAVLSCSCGSACGSWDIREEKVCHCQCARIDWTAARCCKLQVAS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9HD89-1", "uniprot_id": "RETN_HUMAN", "id": "Q9HD89-1", "name": "Resistin", "aln": "MKALCLLLLP----VLGLLVSSKTLCSMEEAINERIQEVAGSLIFRAISSIGLECQSVTSRGDLATCPRGFAVTGCTCGSACGSWDVRAETTCHCQCAGMDWTGARCCRVQP--", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "** *.: ** * ** .* .**.::***.::*:: .**: *:.. *.* :*:*** **:**.* :* .*:***.*****:* :. *****. :***.**** :: ", "identical_positions": 52, "similar_positions": 34, "identity": "45.61%" }, { "cls_id": "homologset.agr.MGI:1888513", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q08464-1", "uniprot_id": "FZD2_RAT", "id": "Q08464-1", "name": "Frizzled-2", "aln": "---------MRARSALPRSALPRLLLPLLLLPAAGPAQFHGEKGISIPDHGFCQPISIPLCTDIAYNQTIMPNLLGHTNQEDAGLEVHQFYPLVKVQCSPELRFFLCSMYAPVCTVLEQAIPPCRSICERARQGCEALMNKFGFQWPERLRCEHFPRHGAEQICVGQNHSEDGTPALLTTAPPSGLQPGAGGTPGGPGGGGAPPRYATLEHPFHCPRVLKVPSYLSYKFLGERDCAAPCEPARPDGSMFFSHHHTRFARLWILTWSVLCCASTFFTVTTSLVAMQRFRYPERPIIFLSGCYTMVSVAYIAGFVLQERVVCNERFSE-------DGYRTVGQGTKKE-GCTILFMMLYFFSMASSIWWVILSLTWFLAAGMKWGHAAIEANSQYFHLAAWAVPAVKTITILAMGQIDGDLLSGVCFVGLNRLDPLRGFVLAPLFVYLFIGTSFLLAGFVSLFRIRTIMKHDGTKTEPLERLMVRIGVFSVLYTVPATIVIACYFYEQAFREHWERSWVSQHCKSLAIPCPAHYTP---RTSPDFTVYMIKYLMTLIVGITSGFWIWSGKTLHSWRKFYTRLTN---SRHGETTV", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9JIP6-1", "uniprot_id": "FZD2_MOUSE", "id": "Q9JIP6-1", "name": "Frizzled-2", "aln": "---------MRARSALPRSALPRLLLPLLLLPAAGPAQFHGEKGISIPDHGFCQPISIPLCTDIAYNQTIMPNLLGHTNQEDAGLEVHQFYPLVKVQCSPELRFFLCSMYAPVCTVLEQAIPPCRSICERARQGCEALMNKFGFQWPERLRCEHFPRHGAEQICVGQNHSEDGAPALLTTAPPSGLQPGAGGTPGGPGGGGSPPRYATLEHPFHCPRVLKVPSYLSYKFLGERDCAAPCEPARPDGSMFFSQEETRFARLWILTWSVLCCASTFFTVTTYLVDMQRFRYPERPIIFLSGCYTMVSVAYIAGFVLQERVVCNERFSE-------DGYRTVVQGTKKE-GCTILFMMLYFFSMASSIWWVILSLTWFLAAGMKWGHEAIEANSQYFHLAAWAVPAVKTITILAMGQIDGDLLSGVCFVGLNSLDPLRGFVLAPLFVYLFIGTSFLLAGFVSLFRIRTIMKHDGTKTEKLERLMVRIGVFSVLYTVPATIVIACYFYEQAFREHWERSWVSQHCKSLAIPCPAHYTP---RMSPDFTVYMIKYLMTLIVGITSGFWIWSGKTLHSWRKFYTRLTN---SRHGETTV", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q14332-1", "uniprot_id": "FZD2_HUMAN", "id": "Q14332-1", "name": "Frizzled-2", "aln": "---------MR-----PRSALPRLLLPLLLLPAAGPAQFHGEKGISIPDHGFCQPISIPLCTDIAYNQTIMPNLLGHTNQEDAGLEVHQFYPLVKVQCSPELRFFLCSMYAPVCTVLEQAIPPCRSICERARQGCEALMNKFGFQWPERLRCEHFPRHGAEQICVGQNHSEDGAPALLTTAPPPGLQPGAGGTPGGPGGGGAPPRYATLEHPFHCPRVLKVPSYLSYKFLGERDCAAPCEPARPDGSMFFSQEETRFARLWILTWSVLCCASTFFTVTTYLVDMQRFRYPERPIIFLSGCYTMVSVAYIAGFVLQERVVCNERFSE-------DGYRTVVQGTKKE-GCTILFMMLYFFSMASSIWWVILSLTWFLAAGMKWGHEAIEANSQYFHLAAWAVPAVKTITILAMGQIDGDLLSGVCFVGLNSLDPLRGFVLAPLFVYLFIGTSFLLAGFVSLFRIRTIMKHDGTKTEKLERLMVRIGVFSVLYTVPATIVIACYFYEQAFREHWERSWVSQHCKSLAIPCPAHYTP---RMSPDFTVYMIKYLMTLIVGITSGFWIWSGKTLHSWRKFYTRLTN---SRHGETTV", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P18537-1", "uniprot_id": "FRIZ_DROME", "id": "P18537-1", "name": "Frizzled", "aln": "MWRQILFILPTLIQGVQRYDQSPLDASPYYRSGGGLMASSGTELDGLPHHNRCEPITISICKNIPYNMTIMPNLIGHTKQEEAGLEVHQFAPLVKIGCSDDLQLFLCSLYVPVCTILERPIPPCRSLCESARV-CEKLMKTYNFNWPENLECSKFPVHGGEDLCVAENTTSSASTAATPTRSVAKVTTRKHQT-----GVESPHRNIGFVCPVQLKTPLGMGYELKVGGKDLHDCGAPCH------AMFFPERERTVLRYWVGSWAAVCVASCLFTVLTFLIDSSRFRYPERAIVFLAVCYLVVGCAYVAGLGAGDSVSCREPFPPPVKLGRLQMMSTITQGHRQTTSCTVLFMALYFCCMAAFAWWSCLAFAWFLAAGLKWGHEAIENKSHLFHLVAWAVPALQTISVLALAKVEGDILSGVCFVGQLDTHSLGAFLILPLCIYLSIGALFLLAGFISLFRIRTVMKTDGKRTDKLERLMLRIGFFSGLFILPAVGLLGCLFYEYYNFDEWMIQWHRDICKPFSIPCPAARAPGSPEARPIFQIFMVKYLCSMLVGVTSSVWLYSSKTMVSWRNFVERLQGKEPRTRAQAYV", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * . * . ...* * : .:*.*. *:**:*.:*.:*.** ******:***:**:******** ****: ** :*::****:*.****:**:.******:** ** ** **:.:.*:***.*.*.:** **.*::**.:* :...:.* .* . . : . * * :* * : *.: * : *. . :**.***. :***.... . * *: :*:.:* ** :*** * *: .*******.*:**: ** :*. **:**: : * *.* *. : *: ** :: .**:*** *** .**: ** *:::******:**** *** :*: ***.******::**::**:.:::**:******** ..* .*:: ** :** **: ******:*******:** **.:*: *****:***.** *: :**. ::.* *** :.* .* : **.::***** :* . * * ::*:*** :::**:**..*::*.**: ***:* ** . :.:: *", "identical_positions": 255, "similar_positions": 162, "identity": "43.0%" }, { "cls_id": "homologset.agr.MGI:1888514", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8K453-1", "uniprot_id": "Q8K453_RAT", "id": "Q8K453-1", "name": "C-X-C motif chemokine 14", "aln": "------------MRLLAAALLLLLLALCASRVDGSKCKCSRKGPKIRYSDVKKLEMKPKYPHCEEKMVIITTKSMSRYRGQEHCLHPKLQSTKRFIKWYNAWNEKRRVYEE", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9WUQ5-1", "uniprot_id": "CXL14_MOUSE", "id": "Q9WUQ5-1", "name": "C-X-C motif chemokine 14", "aln": "------------MRLLAAALLLLLLALCASRVDGSKCKCSRKGPKIRYSDVKKLEMKPKYPHCEEKMVIVTTKSMSRYRGQEHCLHPKLQSTKRFIKWYNAWNEKRRVYEE", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O95715-1", "uniprot_id": "CXL14_HUMAN", "id": "O95715-1", "name": "C-X-C motif chemokine 14", "aln": "MSLLPRRAPPVSMRLLAAALLLLLLALYTARVDGSKCKCSRKGPKIRYSDVKKLEMKPKYPHCEEKMVIITTKSVSRYRGQEHCLHPKLQSTKRFIKWYNAWNEKRRVYEE", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *************** ::***************************************:****:************************************", "identical_positions": 94, "similar_positions": 4, "identity": "84.68%" }, { "cls_id": "homologset.agr.MGI:1888517", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8JI14-1", "uniprot_id": "RHCL2_DANRE", "id": "Q8JI14-1", "name": "Ammonium transporter Rh type C-like 2", "aln": "-----MGNCFGSRG-ICDRPK--------------NTNIRLSLPAV----CFVWQVSMIILFGVFVRYNEEADTNWVYTKKEKNITSDIENDFYFRYPSFQDVHVMIFVGFGFLMTFLKRYSFGAVGFNFLIAAFGLQWALLMQGWFSPLG-DDGKIKIGIENLINADFCVASCLIAYGAVLGKVSPVQLLVMTLFGITLYAVEEFIILRVLNAKDAGGSMVIHTFGAYYGLSISRVLYRPN-LNKSKHMNGSVYHSDVFAMIGTLFLWMFWPSFNSAICNHGDGQHRAAINTYLALASTVLTTVAISSMFEKTGKLDMVHIQNSTLAGGVAVGTAAEFMLMPYGSLIVGFFCGIISTLGYIYLTPFLEERLKIQDTCGIHNLHAMPGVIGGIVGAISAAAASKEVYG---DLGLKNIFSIEGSNVTRL------PTVQGGYQAAALCVALCFGIGGGTFVGLVLKLPIWGD-PADEHCFNDEMYWEVPEDEE-SIIPPVLSYNNHMIPNNKHEEMRETNFAEQS-------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0AB32TTF1-1", "uniprot_id": "A0AB32TTF1_DANRE", "id": "A0AB32TTF1-1", "name": "", "aln": "MLRMTFLAPFASRSRDCATRKRDATETQRDEQTQTQTDTQRNLPCAPDRSAGGVKIAMIILFGVFIRYDEESDSHWIETRKKNNISTDLENDFYYRYPSFQDVHVMIFVGFGFLMTFLKRYSFGSVGFNFLIAAFGIQWALLMQGWFHSFDKEDLKIKIGVENLINADFCVAGCLIAYGACLGKVSPVQLMVLTLFGVTLYAVEEYIILYVLHVRDAGGSMVIHTFGAYYGLTISWVLYRPF-LSQSNHLQRSVYHSDVFAMIGTLFLWMFWPSFNSAIADHGDGQHRAAINTYLSLAASVLTTFALSSLSKKYGKLDMVHIQNATLAGGVAMGTASEFMITPYGSLIVGFCSGIVSTLGYVFLTPLMEKTLKIQDTCGVHNLHAMPGVIGGIVGAVTAACASESVYG---HEGLINMFGFEG-KVNRT------ASVQGGYQAAGIFVAIAFGLVGGALVGGILKLPIWGD-PTDSNCFDDDIYWEVPEEED-ENIPAFGHQNMHHVERTPDAHHRSHV------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9QXP0-1", "uniprot_id": "RHCG_MOUSE", "id": "Q9QXP0-1", "name": "Ammonium transporter Rh type C", "aln": "--------------------------------MAWNTNLRGRLPIT----CLILQVTMVVLFGVFVRYDIQADAHWWLEKKRKNISSDVENEFYYRYPSFQDVHAMVFVGFGFLMTFLQRYGFSAVGFNFLLAAFGIQWALLMQGWFHYFE--EGHIVLSVENIIQADFCVASSCVAFGAVLGKVSPMQLLIMTFFQVTLFTVNEFILLNLIEAKDAGGSMTIHTFGAYFGLTVTWILYRKN-LDQSKQRQSSVYHSDLFAMIGTLFLWIYWPSFNSASSFHGDAQHRAALNTYLSLAASVLTTVTVSSIVHKKGKLDMVHIQNATLAGGVGVGTAAEMMLTPYGALIVGFFCGIFSTLGFAYLTPFLESRHRIQDTCGIHNLHGIPGIIGGIVGAVTAAYSSPDVYG---EPGIVHSFGFGSYKMDWN------KRMQGRSQIFGLLLSLAMALVGGIIVGFILKLPFWGQ-AADENCFEDSIYWEVHEEVN-TVYIPEDLAHKHSTSLVPAMPLVLPTTSASIVPPVPPTPPVSLATSAPSAALVH--------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q7TNN9-1", "uniprot_id": "RHCG_RAT", "id": "Q7TNN9-1", "name": "Ammonium transporter Rh type C", "aln": "--------------------------------MAWNTNLRGRLPIT----CLILQVTMVVLFGVFVRYDIQADAHWWLEKKRKNISSDVENEFYYRYPSFEDVHAMVFVGFGFLMTYLQRYGFSAVGFNFLLAAFGIQWALLMQGWFHFFE--EGHILLSVENLIQADFCVASTCVAFGAVLGKISPMQLLIMTFFQVTLFTVNEFILLNLIEAKDAGGSMTIHTFGAYFGLTVTWILYRKN-LEQSKQRQSSVYHSDLFAMIGTLFLWIYWPSFNSASSFHGDTQHRAALNTYLSLAASVLTTVAVSSVIHKKGKLDMVHIQNATLAGGVGVGTAAEMMLTPYGALIVGFFCGILSTLGFAYLSPFLESRLRIQDTCGIHNLHGIPGIIGGIVGAVTAAYSSPDVYG---EPGIVHSFGFGGYKADWT------KRMQGRSQIFGLLLSLAMALVGGIIVGFILKLPFWGQ-ASDENCFEDAIYWEVPEEVN-TVYIPEDLAHKHSTSLVPAIPLVLSTPSASIVPPVPPTPPASLAT-VTSSSLVH--------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9UBD6-1", "uniprot_id": "RHCG_HUMAN", "id": "Q9UBD6-1", "name": "Ammonium transporter Rh type C", "aln": "--------------------------------MAWNTNLRWRLPLT----CLLLQVIMVILFGVFVRYDFEADAHWWSERTHKNLS-DMENEFYYRYPSFQDVHVMVFVGFGFLMTFLQRYGFSAVGFNFLLAAFGIQWALLMQGWFHFLQ--DRYIVVGVENLINADFCVASVCVAFGAVLGKVSPIQLLIMTFFQVTLFAVNEFILLNLLKVKDAGGSMTIHTFGAYFGLTVTRILYRRN-LEQSKERQNSVYQSDLFAMIGTLFLWMYWPSFNSAISYHGDSQHRAAINTYCSLAACVLTSVAISSALHKKGKLDMVHIQNATLAGGVAVGTAAEMMLMPYGALIIGFVCGIISTLGFVYLTPFLESRLHIQDTCGINNLHGIPGIIGGIVGAVTAASASLEVYG---KEGLVHSFDFQGFNGDWT------ARTQGKFQIYGLLVTLAMALMGGIIVGLILRLPFWGQ-PSDENCFEDAVYWEMPEGNS-TVYIPEDPTFKPSGPSVPSVPMVSPLPMASSVPLVP--------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A6M3Q9I2-1", "uniprot_id": "A0A6M3Q9I2_DROME", "id": "A0A6M3Q9I2-1", "name": "", "aln": "---------------------------------MHSPAAKVSGYVV----LMIVQIIFLVLFWLFVRYEKTA-----LPLAIDAEDAGSANEHVSKYPQFQDIQVMIFIGFGFLMTFLRKYGYSATGFTLFMAALVVQWAVLMKGFLHMEG---GKISLSLENIIDADIAAAVPLISMGALLGRTTPIQLLCMSVFEVALFAANEYLALHVFSICDCGGSITVHAFGAYFGLAVALMLRPASDQNETGKLEGASYTSDIFAMIGTTFLWVYWPSFNSVLAD-GAGGERAILNTFLSLAAATVTTFVVSALVSHENKLDMVHVQNSTLAGGVAVGTVCNLLLGAHGAVLIGIIAGTVSVLGYRYLTPWMTANLRLHDTCGVHNLHGMPALISAIASAIYASMATVGEYQSELQDIFPAMVGTNGTETKIMGGLGRNATSQAGYQLFGIAVTLLIAIGGGILTGAVLKYTNFRN-LKKDEHHQDEHYWEVPAAENKEEYLNMLAKLLDDDAAATNSNSQSAANFNWRPFLLRNWNAIVPANNLYVRGALH--------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P53390-1", "uniprot_id": "MEP3_YEAST", "id": "P53390-1", "name": "Ammonium transporter MEP3", "aln": "-----------------------------------MARGDGHLWTET---YDSSTVAFMILGAALVFFMVPGLGFLYSGLAR------RKSALALIWVVIMATLVGILQWYFWGYSLAFSKTATNNKFIGNLDSFGFRNVYGKISDDSTYPELIYAIFQMMFMCVALSIIAGATAERGKLFPHMVFLFVFATLVYCPITYWIWAPGGWAYQWGVLDWAGGGNIEILSAVAGFVYSYFLGRRKE----NLLINFRPHNVSMVTLGTSILWFGWLLFNAASSLSPNMRSVYAFMNTCLSATTGGMTWCLLDY-RSEKKWSTVGLCSGIICG-LVAATPSSGCITLYGSLIQGIIAGVVCNF-----ATKIKYYLKVDDSLDLLAEHGIAGVVGLIFNALFAADWVIGMDG--TTKHKGGWLTHNWKQMYIQ------IAYIGASAGYCAVVTAIICFVLGKIPGVHLRVTEEAEALGLDEDQIGEFAYDYVEVRR-DYYQWGVDTDALHTTCNGANSASETNPTEDSQNSSLSSATVSGQNEKSNNPKLHHAKEA---", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P40260-1", "uniprot_id": "MEP1_YEAST", "id": "P40260-1", "name": "Ammonium transporter MEP1", "aln": "----------------------------------MESRTTGPLTTET---YDGPTVAFMILGAALVFFMVPGLGFLYSGLAR------RKSALALIWVVLMATLVGILQWYFWGYSLAFSKSAPNNKFIGNLDSFGFRNVYGKKFDEDAYPELAYATFQMMFSCVNLSIIAGATAERGRLLPHMVFLFILATIGYCPVTYWIWSPGGWAYQWGVLDWAGGGNIEILSAVSGFVYSWFLGKRNE----KLLINFRPHNVSLVTLGTSILWFGWLLFNSASSLSPNLRSVYAFMNTCLSAITGGMTWCLLDY-RSEKKWSTVGLCSGIISG-LVAATPSSGCITLYGSLIQGIVAGVVCNF-----ATKLKYYAKVDDAMDILAEHGVAGVIGLIFNALFGADWVIGMDG--TTEHEGGWVTHNYKQMYKQ------IAYIAASIGYTAAVTAIICFVLGYIPGMRLRISEEAEEAGMDEDQIGEFAYDYVEVRR-DYYLWGVDEDSQRSDVN-HRVNNAHLAAERSSSGTNSSSDGNGEMIQSEKILPIHQEDPANR", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P41948-1", "uniprot_id": "MEP2_YEAST", "id": "P41948-1", "name": "Ammonium transporter MEP2", "aln": "------------------------MSYNFTGTPTGEGTGGNSLTTDLNTQFDLANMGWIGVASAGVWIMVPGIGLLYSGLSR------KKHALSLLWASMMASAVCIFQWFFWGYSLAFSHNTRGNGFIGTLEFFGFRNVLGAPSSVSSLPDILFAVYQGMFAAVTGALMLGGACERARLFPMMVFLFLWMTIVYCPIACWVWNAEGWLVKLGSLDYAGGLCVHLTSGHGGLVYALILGKRNDPVTRKGMPKYKPHSVTSVVLGTVFLWFGWMFFNGGSAGNATIRAWYSIMSTNLAAACGGLTWMVIDYFRCGRKWTTVGLCSGIIAG-LVGITPAAGFVPIWSAVVIGVVTGAGCNL-----AVDLKSLLRIDDGLDCYSIHGVGGCIGSVLTGIFAADYVNATAGSYISPIDGGWINHHYKQVGYQ------LAGICAALAWTVTVTSILLLTMNAIPFLKLRLSADEEELGTDAAQIGEFTYEESTAYIPEPIRSKTSAQMPPPHENIDDKIVGNTDAEKNSTPSDASSTKNTDHIV---------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : : : . : : . :: : : : * : : .: . : : : . . : :: : * .*. :. .. *: : .* . . :** :**. * **. . : . * : : * * : .. :.* : * . : .::: *. * . : : : ::.* . *.: . :. : .: .: . : :: : : . : *: . : . . :: ", "identical_positions": 22, "similar_positions": 93, "identity": "3.96%" }, { "cls_id": "homologset.agr.MGI:1888518", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I5ZPB5-1", "uniprot_id": "A0A8I5ZPB5_RAT", "id": "A0A8I5ZPB5-1", "name": "", "aln": "-----------------MEPWKQCAQWLIHCKVLPANHRVTWDSAQVFDLAQTLRDGVLLCQLLNNLRPHSINLKEINLRPQMSQFLCLKNIRTFLAACCDTFGMKKSELFEAFDLFDVRDFGKVIETLSRLSRT-------PIALATGIRPFPTEESVNDEDIYKGLPDLIDETRVEDEEDLYDCVYGEDEGGEVYEDLMKAEEAHQAKSQENDIRSCCLAEIRQTEEKYTETLESIEKYFMAPLKRFLTAAEFDSVFINIPDLVKVHRSLMQEIHDSIVNKDDHNLYQVFINYKERLVIYGQYCSGVESAISSLDYISKTKEDVRLKLEECSKRANNGKFTLRDLLVVPMQRVLKYHLLLQELVKHTHDPMEKS-NLKLALDAMKDLAQYVNEVKRDNETLREIKQFQLSIENLNQP-------VLLFGRPQGDGEIRITTLDKHTKQERHIFLFDLAVIVCKRK-----GDNYEMKEIIDLQQYKIANNPTTDKE--NKKWSYGFYLIHTQGQNGLEFYCKTKDLKKKWLEQFEMALSNIRPDYADSNFHDFKMHTFTRVTSCRVCQMLLRGTFYQGYLCFKCGAKAHKECLGRVDNCGRVNSVEQGPFKPPEKRTNGLRRASRQVDPGLPKMRVIRNYTGTPPPALHEGPPLHIQAGDTVELLRGEAHTVFWQGRNLASGEVGFFPSDAVKPSPCVPKPVDYSCQPWYAGPMERLQAETELINRVNSTYLVRLR-----TKESGEYAISIKYNN-EAKHIKILTRDG----FFHIAENRKFKSLMELVEYYKHHSLKEGFRTLDTTLQFPYKEPEHASGQRG---------NRTGN-----------SLLSPKVLGIAIARYDFCARDMRELSLLKGDMVKIYTKMSANGWWRGEVNGRVGWFPSTYVEEDE------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9R0C8-1", "uniprot_id": "VAV3_MOUSE", "id": "Q9R0C8-1", "name": "Guanine nucleotide exchange factor VAV3", "aln": "-----------------MEPWKQCAQWLIHSKVLPPNHRVTWDSAQVFDLAQTLRDGVLLCQLLNNLRPHSINLKEINLRPQMSQFLCLKNIRTFLAACCDTFGMRKSELFEAFDLFDVRDFGKVIETLSRLSRT-------PIALATGIRPFPTEESINDEDIYKGLPDLIDETRVEDEEDLYDCVYGEDEGGEVYEDLMKAEEAQQPKSQENDIRSCCLAEIRQTEEKYTETLESIEKYFMAPLKRFLTAAEFDSVFINIPDLVKVHRSLMQEIHDSIVNKDDQNLYQVFINYKERLVIYGQYCSGVESAISNLDYISKTKEDVKLKLEECSKRANNGKFTLRDLLVVPMQRVLKYHLLLQELVKHTHDPMEKA-NLKLALDAMKDLAQYVNEVKRDNETLREIKQFQLSIENLNQP-------VLLFGRPQGDGEIRITTLDKHTKQERHIFLFDLAVIVCKRK-----GDNYEMKEIIDLQQYKIANNPTTDKE--NKKWSYGFYLIHTQGQNGLEFYCKTKDLKKKWLEQFEMALSNIRPDYADSNFHDFKMHTFTRVTSCRVCQMLLRGTFYQGYLCFKCGAKAHKECLGRVDNCGRVNSVEQGPFKPPEKRTNGLRRASRQVDPGLPKMQVIRNYTGTPAPGLHEGPPLHIQAGDTVELLRGDAHSVFWQGRNLASGEVGFFPSDAVKPSPCVPKPVDYSCQPWYAGPMERLQAETELINRVNSTYLVRHR-----TKESGEYAISIKYNN-EAKHIKILTRDG----FFHIAENRKFKSLMELVEYYKHHSLKEGFRTLDTTLQFPYKEPEQPAGQRG---------NRTGN-----------SLLSPKVLGIAIARYDFCARDMRELSLLKGDMVKIYTKMSANGWWRGEVNGRVGWFPSTYVEEDE------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9UKW4-1", "uniprot_id": "VAV3_HUMAN", "id": "Q9UKW4-1", "name": "Guanine nucleotide exchange factor VAV3", "aln": "-----------------MEPWKQCAQWLIHCKVLPTNHRVTWDSAQVFDLAQTLRDGVLLCQLLNNLRAHSINLKEINLRPQMSQFLCLKNIRTFLTACCETFGMRKSELFEAFDLFDVRDFGKVIETLSRLSRT-------PIALATGIRPFPTEESINDEDIYKGLPDLIDETLVEDEEDLYDCVYGEDEGGEVYEDLMKAEEAHQPKCPENDIRSCCLAEIKQTEEKYTETLESIEKYFMAPLKRFLTAAEFDSVFINIPELVKLHRNLMQEIHDSIVNKNDQNLYQVFINYKERLVIYGQYCSGVESAISSLDYISKTKEDVKLKLEECSKRANNGKFTLRDLLVVPMQRVLKYHLLLQELVKHTTDPTEKA-NLKLALDAMKDLAQYVNEVKRDNETLREIKQFQLSIENLNQP-------VLLFGRPQGDGEIRITTLDKHTKQERHIFLFDLAVIVCKRK-----GDNYEMKEIIDLQQYKIANNPTTDKE--NKKWSYGFYLIHTQGQNGLEFYCKTKDLKKKWLEQFEMALSNIRPDYADSNFHDFKMHTFTRVTSCKVCQMLLRGTFYQGYLCFKCGARAHKECLGRVDNCGRVNSGEQGTLKLPEKRTNGLRRTPKQVDPGLPKMQVIRNYSGTPPPALHEGPPLQLQAGDTVELLKGDAHSLFWQGRNLASGEVGFFPSDAVKPCPCVPKPVDYSCQPWYAGAMERLQAETELINRVNSTYLVRHR-----TKESGEYAISIKYNN-EAKHIKILTRDG----FFHIAENRKFKSLMELVEYYKHHSLKEGFRTLDTTLQFPYKEPEHSAGQRG---------NRAGN-----------SLLSPKVLGIAIARYDFCARDMRELSLLKGDVVKIYTKMSANGWWRGEVNGRVGWFPSTYVEEDE------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AC58GX97-1", "uniprot_id": "A0AC58GX97_DANRE", "id": "A0AC58GX97-1", "name": "", "aln": "-----------------MEYWRQCSLWLINCKVLPRNHRVTADSAQVFDLAQTLRDGVLLCQLLNNLRPDTINLKEINLRPQMSQFLCLKNIRTFLSACCEEFGMKKSDLFEAFDLFDVRDFGKVIDTLSKLSYT-------PVAQQSGIRSFPTEESTENEDIYIHLADLIDE---ELEEDVYDPVYGDIEGGEVYEDLMRTEAAVS-QAAEVDIRSCCLLEIKQTEAKYTETLETIEKYFMIPLMKFIPATDIDKVFINIPDLVKVHKGLMGEIQDCVQNKNAENLHQIFITYKDRLLLYGKYCSHVESAISLLDFICKEKEGVRLKLEECSKRANNGKFTLRDLLVVPMQRVLKYPLLLQELVKYTNDGPEKS-NLRIALDAMRDLAQYVNEVKRDVETLREIDQYQRSIENLNQS-------LLSYGRPKGDGEVRLVSNLDKRRQDRHIFLFDAAVIICKRR-----GDNYEMKEVIDLSHFKITNN-LADKD--CRKWSSGFYLTHQQGQSGFEFLFKTKELKKKWLDQFEMAISNIRPENATFNSHHFRMHTFERATTCSSCRMLLRGIFNQGYLCPKCGNGAHKGCLGKLGVCGRTGAAVQ---KPQRKTTP-----RKQEDPGLPKMLVIRDYFGVSKP--QGGQALNAQIGDVIEVVYADPHSSWWQGKILTTQETGFFPSDAVKPCPCVPRTVDYSSQPWFAGPMERHHAESELMERENSTYLVRYR-----SRESREYAISIKYNN-DVKHLKVLTKEG----CFYIAESRTFKNVLGLVEYYKQHSLKEGFRTLDTTLQVPFKELGTGLRTAAPVLCGLSVLSPTSYNFVPPSPSPFWSVLTPRVLGIALARYDFSSRDTRELSLQVGDLVKIYIKCTN-GWWKGEVNGRVGWFPSTYVEEEE------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9NHV9-1", "uniprot_id": "VAV_DROME", "id": "Q9NHV9-1", "name": "Protein vav", "aln": "MASSSSSNSFGGVAGVNGDLWRECVAWLTRCKVIPPDHKAAQPDAEIRILAMTLRDGVLLCNLVIHLDPSSLDPREFNRKPQMAQFLCSKNIKLFLDVCHNNFGIRDADLFEPTMLYDLTNFHRVLITLSKLSQCRKVQQLHPDLIGFNLQLSPTERSHSDEAIYKDLHSTTTDNIACNGTGYDHTNTKEEEVYQDLCALHRTSRSQTASSTSFEQRDYVIRELIDTESNYLDVLTALKTKFMGPLERHLNQDELRLIFPRIRELVDIHTKFLDKLRESLTPNAKVKMAQVFLDFREPFLIYGEFCSLLLGAIDYLADVCKKNQIIDQLVQKCERDYNVGKLQLRDILSVPMQRILKYHLLLDKLVKETSPLHDDYRSLERAKEAMIDVSQYINEVKRDSDHLVIIQKVKDSICDIHLLQNGNGSDLLQYGRLLLDGELHIKAHEDQKTKLRYAFVFDKILIMVKALHIKTGDMQYTYRDSHNLADYRVEQSHSRRTIGRDTRFKYQLLLARKSGKTAFTLYLKSEHERDKWRKALTEAMESLEPPGCQSTDHKMEIYTFDAPTTCRHCSKFLKGRIHQGYRCKVCQISVHKGCISSTGRCKQN--------------------------------------------------------------------------------------PVSVPPPVCDRQLSEFN---WFAGNMDRETAAHRLENRRIGTYLLRVRPQGPSTAHETMYALSLKTDDNVIKHMKINQENSGDSMLYCLSSRRHFKTIVELVSYYERNDLGENFAGLNQSLQWPYK----------------------------------------EVIATALYDYEPKAGSNQLQLRTDCQVLVIGKDGDSKGWWRGKIGDTVGYFPKEYVQEQKLASEEL", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : *::* ** ..**:* :*:.: .*:: ** *********:*: :* . ::: :*:* :***:**** ***: ** .* : **::.::***. *:*: :* :*: ***:** * .:: ***.* .:* ** * . : . . : * : * ::. : .. . : *. : *: :** :* :.* :::. ** ** :.: :: :* .* :**.:* :: ::::.: : :: *:*: ::: :::**::** : .**. * :.* :: : :::*.: * **: ***:* *****:*** ***::*** * :. .*. * :** *::**:****** : * *.: : ** ::: :* :** ***::: : .: : *: *:** :*: * . :* :: :* .::: :. . ::. : * : .*:..: : *::. :.** . : *:..:.* . . *.:.::** *:* * :*:* : *** * * .** *:. . * : . :* * * : ::. *:** *:* * .* :* .***:* * : .. **:*:* :: **:*: .:. : ::. * **.:: **.**:::.* *.* *: :** *:* .*:. *: *: : . : ::: * . ***:*::.. **:**. **:*:: ", "identical_positions": 218, "similar_positions": 260, "identity": "23.64%" }, { "cls_id": "homologset.agr.MGI:1888519", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "F1LRJ8-1", "uniprot_id": "F1LRJ8_RAT", "id": "F1LRJ8-1", "name": "LIM homeobox transcription factor 1-alpha", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MLDGLKMEENFQSAIET------------------------------------------SASFSSLLGRAVS------------PKSVCEGCQRVISDRFLLRLNDSFWHEQCVQCASCKEPLETTCFYRDKKLYCKYHYEKLFAVKCGGCFEAIAPNEFVMRAQ-KSVYHLSCFCCCVCERQLQKGDEFVLKEGQLLCKGDYEKERELLSLVSPAASDSGKSDDEESLCKS---AHGAGKGASEDGKDHKR-PKRPRTILTTQQRRAFKASFEVSSKPCRKVRETLAAETGLSVRVVQVWFQNQRAKMKKLARRQQQQQQDQQ-NTQRLSSAQTNGSGNAGMEGIMNPYT-TLPTPQQLLAIE--QSVYNSDPFRQGL--TPPQMPGDHMHPYGAEPL------FHDLDSDDTSLSNLGDCFLATSEAG---------------PLQSRVGNPIDHLYSMQNSYFTS--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9JKU8-1", "uniprot_id": "LMX1A_MOUSE", "id": "Q9JKU8-1", "name": "LIM homeobox transcription factor 1-alpha", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MLDGLKMEENFQSAIET------------------------------------------SASFSSLLGRAVS------------PKSVCEGCQRVISDRFLLRLNDSFWHEQCVQCASCKEPLETTCFYRDKKLYCKYHYEKLFAVKCGGCFEAIAPNEFVMRAQ-KSVYHLSCFCCCVCERQLQKGDEFVLKEGQLLCKGDYEKERELLSLVSPAASDSGKSDDEESLCKS---AHGAGKGASEDGKDHKR-PKRPRTILTTQQRRAFKASFEVSSKPCRKVRETLAAETGLSVRVVQVWFQNQRAKMKKLARRQQQQQQDQQ-NTQRLTSAQTNGSGNAGMEGIMNPYT-TLPTPQQLLAIE--QSVYNSDPFRQGL--TPPQMPGDHMHPYGAEPL------FHDLDSDDTSLSNLGDCFLATSEAG---------------PLQSRVGNPIDHLYSMQNSYFTS--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8TE12-1", "uniprot_id": "LMX1A_HUMAN", "id": "Q8TE12-1", "name": "LIM homeobox transcription factor 1-alpha", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MLDGLKMEENFQSAIDT------------------------------------------SASFSSLLGRAVS------------PKSVCEGCQRVILDRFLLRLNDSFWHEQCVQCASCKEPLETTCFYRDKKLYCKYDYEKLFAVKCGGCFEAIAPNEFVMRAQ-KSVYHLSCFCCCVCERQLQKGDEFVLKEGQLLCKGDYEKERELLSLVSPAASDSGKSDDEESLCKS---AHGAGKGTAEEGKDHKR-PKRPRTILTTQQRRAFKASFEVSSKPCRKVRETLAAETGLSVRVVQVWFQNQRAKMKKLARRQQQQQQDQQ-NTQRLSSAQTNGGGSAGMEGIMNPYT-ALPTPQQLLAIE--QSVYSSDPFRQGL--TPPQMPGDHMHPYGAEPL------FHDLDSDDTSLSNLGDCFLATSEAG---------------PLQSRVGNPIDHLYSMQNSYFTS--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q5RI65-1", "uniprot_id": "Q5RI65_DANRE", "id": "Q5RI65-1", "name": "", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MTLWIMMCQMDDT------------------------------------------FVVFADMWR-----------------KSVCEGCNELIRDRYLLRVQDGLWHERCLHCASCREPLKDTCFLRNKTLYCKRDYQKLFVVRCQGCSEIISPSELVMRAQGSAVFHLRCFCCCVCGCRLQKGDHCVLRGDGLFCATHFHN-----QLASPTSSDSGKSEDIEEDNDDEDNLKTAGESNITGDVEHKR-PKRPRTILTTQQRRAFKASFEVSSKPCRKVRETLAAETGLSVRVVQVWFQNQRAKMKKLVRRQQQQKQTVCPQEKRESPSQQHTATSCGALPVELECAGSYPLPQQNLSLD--SQSLKLDPFRQGL--TPPQMPGDHMHPYGCDTL------YDETDSD--PLCHFGDCMSS-SELS---------------FLT-----PIDRLYSMQDSYFAS--", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VTW5-1", "uniprot_id": "Q9VTW5_DROME", "id": "Q9VTW5-1", "name": "", "aln": "MLEFYPMPTNLNPVGGSLYSLQQNHGGARFLDNPNPGSMTASSGNSLHLSNSNNNLPTSISGNNSPTATASLTGQHQQHQQQQHQQQQQHPHQQHQQHQQQHAASTTPVPINSCPTPTGHSPLSSSSSNSNHNNNNNNNNGGSSSNNLHSACNTLTAAAVAAASAAAVAAPSPAGTSVATSQLGGAVAAAIAAAAAAAAAATTPTSTGPAATGSGNANGSGNGNGNGNGNGNGNGNGNGGGAATASAAAASKLSADCSGRTEVGHIKCEKNFELCEGCGQKIHDRFLMNVGDANWHEQCLACCYCGMQLHHTCYVRNSKLYCKMDYDRLFGVKCSSCCHAILPQELVMRPIPNFVFHLPCFVCYACRLPLQKGEQFMLRDGQLFCYR--HDLEKEMFLAAAAAQHCG--------------FVGLDEEDLLRPRDGRRGPKRPRTILTSQQRKQFKASFDQSPKPCRKVREALAKDTGLSVRVVQVWFQNQRAKMKKIQRKAKQNGGSGGGSGSGRGTGNSSATDDKDTNDKEDKCVKQELGGDSSGYLGGLDSTFASQPLNPNLPFSPDDYPANSNDSFCSSDLSLDGSNFDQLDDDADSLSLNNLELQSTSSSGNQHSHSHSNPHDMLANLNNSLINPIDKLYLMQNSYFSSEH", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : * . :. .:**** . * **:*:.: *. ***:*: *. * *. **: *:..**** .*::** *:* .* . * *.*:***. . *:** ** * .* ****:. :*: . *:* .. *.:.::...* .: : :* *********:***: *****: *.********:** :*********************: *: :*: . . ..: . . . :. : .. :*:. .* :* : *.: ..: .. * :.: *.* .*. . : : *. . * ***:** **:***:* ", "identical_positions": 125, "similar_positions": 102, "identity": "19.05%" }, { "cls_id": "homologset.agr.MGI:1888520", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9ESU6-1", "uniprot_id": "BRD4_MOUSE", "id": "Q9ESU6-1", "name": "Bromodomain-containing protein 4", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSTESGPGTRLRNLPVMGDGLETSQMS-TTQAQAQPQPANAASTNPPPPETSNPNKPKRQTNQLQYLLRVVLKTLWKHQFAWPFQQP---VDAVKLNLPDYYKIIKTPMDMGTIKKRLENNYYWNAQECIQDFNTMFTNCYIYNKPGDDIVLMAEALEKLFLQKINELPTEETEIMIVQAKG---------------------RGRGRKE------TGAAKPGVSTVPNTTQAS-------------TSPQTQTPQQNPPPPVQATTHPFPAVTPDLIAQPPVMTMVPPQP-----------------------------------------------------------------------------------------LQTPSPVPPQPPPPPAPVPQPVQSH----PPIIATTPQPVKTKKGVKRKADTTTPTTIDPIHEPPSLAPEPKTAKLGPRRESSRP----------------VKPPKKDVPDSQQHPGPEK---SSKISEQLKCCSGILKEMFAKKHAAYAWPFYKPVDVEALGLHDYCDIIKHPMDMSTIKSKLESREYRDAQEFGADVRLMFSNCYKYNPPDHEVVAMARKLQDVFEMRFAKMPDEPEEPVVTVSSPAVPPP----------------TKVVAPPSSSDSSSDSSSDSDSSTDD---SEEERAQRLAELQEQLKAVHEQLAALSQPQQNKPKKKEKDKKEKK--------------------------------------------------------------------------------------------------------------------KEKHKKKE--------------EVEENKKSKTKELPPKKTK---KNNSSNSNVSKKEP---------------------------------------------------------------VPTKTKPPPTYESEEE---------------DKCKPMSYEEKRQLSLDINKLPGEKLGRVVHIIQSREPS--LKNSNPDEIEIDFETLKPSTLRELERYVTSCLRKK--RKPQAEKVDVIAGSSKMKGFSSSESESTSESSSSDSEDSETEMAPKSKKKGHTGRDQKKHHHHHHPQMQPAPAPVPQQPPPPPQQPPPPPPPQQQQQQ----PPPPPPPPSMPQQTAPAMKSSPPPFITAQVPVLEP-QLPGSVFDPIGHFTQPILHLPQPE--LPPHLPQPP-----EHSTPPHLNQHAVVSPPALHNALPQQPSRPSNR-----------AAALPPKPTR-----------------------PPAVSPALAQPPLLPQPP-----------------------MAQPPQVLLEDEEPPAPPLTSMQMQLYLQQLQ-KVQPPTPLLPSVKVQSQPPPPLPPPPHPSVQQQQLQPQPPPPPPPQPQPPPQQQHQPPPRPVHLPSMPFSAHIQQPPPPPG-----------QQPTHPPPGQQPPPPQPAKPQQVIQH-----HPSPRHHKSDPYSAGHLREAPSPLMIHSPQMPQFQSLTHQSPPQQNVQPKKQVKGRAEPQPPGPVMGQGQGCPPASPAAVPMLSQELRPPSVVQPQPLVVVKEEKIH-SPIIRSEPFSTSLRPEPPKHPEN-IKAPVHLPQRPEMKPVDIGRPVIRPPEQSAPPPGAPDKDKQKQ----------EPKTPVAPKK--DLKIKNMGSWASLVQK-------HPTTPSSTAKSSSDSFEHFRRAAREK------EEREKALKAQAEHAEKEKERLRQERMR-------------------------------------------------SREDEDALEQARRAHEEARRRQEQQ----------------------------------------------------------------------------------------------------------------------------------QQQQQQRQEQQQQQQQ-------AAAVAAASAPQAQSSQPQSMLDQQ---------------------------------RELARKREQERRRREAMAATIDMNFQSDLLSIFEENLF", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D3ZGX8-1", "uniprot_id": "D3ZGX8_RAT", "id": "D3ZGX8-1", "name": "", "aln": "MTRGRARSVRDDISALAAAAGLFVLLSRSRGTEAVAAAAAAAAAAAAGGARRQAGPVSAAAQQARRTGPGLAQASRTACGGVRPSVSGEDRCPSRPRGGLPGAPRRGPRNLHCVMEPVRHHLRHRRGAGVGRPQFRGPGACCCSRSAGAARAVGAAAAGWARGLSIGAVAAAAVPLGAGCSRERDRGRGRAGRRDGRPGAGGGRAKLPALPAAAILSSEEEEEEEAAAAGSAVRARPVVPGEECDGITSMSTESGPGTRLRNLPVMGDGLETSQMS-TTQAQAQPQSANAASTNPPPPETSNPNKPKRQTNQLQYLLRVVLKTLWKHQFAWPFQQP---VDAVKLNLPDYYKIIKTPMDMGTIKKRLENNYYWNAQECIQDFNTMFTNCYIYNKPGDDIVLMAEALEKLFLQKINELPTEETEIMIVQAKG---------------------RGRGRKE------TGTAKPGVSTVPNTTQAS-------------TSPQTQMPQQNPPPPVQATTHPFPAVTPDLIAQPPVMTMVPPQP-----------------------------------------------------------------------------------------LQTPSPVPPQPPPPPAPVPQPVQSH----PPIIATTPQPVKTKKGVKRKADTTTPTTIDPIHEPPSLAPEPKTAKLGPRRESSRP----------------VKPPKKDVPDSQQHPGPEK---SSKISEQLKCCSGILKEMFAKKHAAYAWPFYKPVDVEALGLHDYCDIIKHPMDMSTIKSKLESREYRDAQEFGADVRLMFSNCYKYNPPDHEVVAMARKLQDVFEMRFAKMPDEPEEPVVTVSSPAVPPP----------------TKVVAPPSSSDSSSDSSSDSDSSTDD---SEEERAQRLAELQEQLKAVHEQLAALSQPQQNKPKKKEKDKKEKK--------------------------------------------------------------------------------------------------------------------KEKHKKKE--------------EMEENKKSKAKELPPKKTK---KNNSSNSNVSKKEP---------------------------------------------------------------APTKTKPPPTYESEEE---------------DKCKPMSYEEKRQLSLDINKLPGEKLGRVVHIIQSREPS--LKNSNPDEIEIDFETLKPSTLRELERYVTSCLRKK--RKPQAEKVDVIAGSSKMKGFSSSESESTSESSSSDSEDSETEMAPKSKKKGHTGRDQKKHHHHHHPQMQPAPAPVPQQPPPPPQQPPPPPPPQQQQQQQQQQPPPPPPPPSMPQQTAPAMKSSPPPFITAQVPVLEP-QLPGSVFDPIGHFTQPILHLPQPE--LPPHLPQPP-----EHSTPPHLNQHAVVSPPALHNALPQQPSRPSNR-----------AAALPPKPAR-----------------------PPAVSPALAQPPLLPQPP-----------------------MAQPPQVLLEDEEPPAPPLTSMQMQLYLQQLQ-KVQPPTPLLPSVKVQSQPPPPLPPPPHPSVQQQQLQQQPPPPPPPQPQPPPQQQHQPPPRPVHLPSMPFSAHIQQPPPPTG-----------QQPTHPPPGQQPPPPQPAKPQQVIQH-----HPSPRHHKSDPYSAGHLREAPSPLMIHSPQMPQFQSLTHQSPPQQNVQPKK---------------------------------QELRPPSVVQPQPLVVVKEEKIH-SPIIRSEPFSTSLRPEPPKHPEN-MKAPVHLPQRPEMKPVDVGRPVIRPPEQSAPPPGAPDKDKQKQ----------EPKTPVAPKK--DLKIKNMGSWASLVQK-------HPTTPSSTAKSSSDSFEHFRRAAREK------EEREKALKAQAEHAEKEKERLRQERMR-------------------------------------------------SREDEDALEQARRAHEEARRRQEQQ----------------------------------------------------------------------------------------------------------------------------------QQQQRQEQ-QQQQQQQ-------AAAVAAASAPQAQSSQPQSMLDQQ---------------------------------RELARKREQERRRREAMAATIDMNFQSDLLSIFEENLF", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O60885-1", "uniprot_id": "BRD4_HUMAN", "id": "O60885-1", "name": "Bromodomain-containing protein 4", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSAESGPGTRLRNLPVMGDGLETSQMS-TTQAQAQPQPANAASTNPPPPETSNPNKPKRQTNQLQYLLRVVLKTLWKHQFAWPFQQP---VDAVKLNLPDYYKIIKTPMDMGTIKKRLENNYYWNAQECIQDFNTMFTNCYIYNKPGDDIVLMAEALEKLFLQKINELPTEETEIMIVQAKG---------------------RGRGRKE------TGTAKPGVSTVPNTTQAS-------------TPPQTQTPQPNPPP-VQATPHPFPAVTPDLIVQTPVMTVVPPQP-----------------------------------------------------------------------------------------LQTPPPVPPQPQPPPAPAPQPVQSH----PPIIAATPQPVKTKKGVKRKADTTTPTTIDPIHEPPSLPPEPKTTKLGQRRESSRP----------------VKPPKKDVPDSQQHPAPEK---SSKVSEQLKCCSGILKEMFAKKHAAYAWPFYKPVDVEALGLHDYCDIIKHPMDMSTIKSKLEAREYRDAQEFGADVRLMFSNCYKYNPPDHEVVAMARKLQDVFEMRFAKMPDEPEEPVVAVSSPAVPPP----------------TKVVAPPSSSDSSSDSSSDSDSSTDD---SEEERAQRLAELQEQLKAVHEQLAALSQPQQNKPKKKEKDKKEKK--------------------------------------------------------------------------------------------------------------------KEKHKRKE--------------EVEENKKSKAKEPPPKKTK---KNNSSNSNVSKKEP---------------------------------------------------------------APMKSKPPPTYESEEE---------------DKCKPMSYEEKRQLSLDINKLPGEKLGRVVHIIQSREPS--LKNSNPDEIEIDFETLKPSTLRELERYVTSCLRKK--RKPQAEKVDVIAGSSKMKGFSSSESESSSESSSSDSEDSETEMAPKSKKKGHPGREQKKHHHHHHQQMQQAPAPVPQQPPPPPQQPPPPPPPQQQQQP-----PPPPPPPSMPQQAAPAMKSSPPPFIATQVPVLEP-QLPGSVFDPIGHFTQPILHLPQPE--LPPHLPQPP-----EHSTPPHLNQHAVVSPPALHNALPQQPSRPSNR-----------AAALPPKPAR-----------------------PPAVSPALTQTPLLPQPP-----------------------MAQPPQVLLEDEEPPAPPLTSMQMQLYLQQLQ-KVQPPTPLLPSVKVQSQPPPPLPPPPHPSVQQQ-LQQQPPPPPPPQPQPPPQQQHQPPPRPVHLQPMQFSTHIQQPPPPQG-----------QQPPHPPPGQQPPPPQPAKPQQVIQH-----HHSPRHHKSDPYSTGHLREAPSPLMIHSPQMSQFQSLTHQSPPQQNVQPKK---------------------------------QELRAASVVQPQPLVVVKEEKIH-SPIIRSEPFSPSLRPEPPKHPES-IKAPVHLPQRPEMKPVDVGRPVIRPPEQNAPPPGAPDKDKQKQ----------EPKTPVAPKK--DLKIKNMGSWASLVQK-------HPTTPSSTAKSSSDSFEQFRRAAREK------EEREKALKAQAEHAEKEKERLRQERMR-------------------------------------------------SREDEDALEQARRAHEEARRRQEQQ----------------------------------------------------------------------------------------------------------------------------------QQQRQEQQ--QQQQQQ-------AAAVAAAATPQAQSSQPQSMLDQQ---------------------------------RELARKREQERRRREAMAATIDMNFQSDLLSIFEENLF", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F1R5H6-1", "uniprot_id": "BRD4_DANRE", "id": "F1R5H6-1", "name": "Bromodomain-containing protein 4", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MGDGLDAVQMSGSSSSQGQPSSQAPSSFNPNPPETSNPTRPKRQTNQLQYLLKVVLKSLWKHQFAWPFHAP---VDAVKLNLPDYYKIIKNPMDMGTIKKRLESAFYTSAQECIQDFNTMFTNCYIYNKPGDDIVLMAEALEKVFLTKISEMPQQEVEISTTAGKG---------------------RGRGRRDPDMNMKVGPVLEPLTASPQTRGLSNLT----------PGPQTRGPPQGPPTLPPQPIVQIQALPPRVPPSLPTIPLHAPQLGPPFS-------------------------------------------------------------------------------LGPTDCNPPAPIITAVPPPTQTALPPVHIQQSAAPPILQTPISIPNKRKSQKRKADTTTPTANDQLNE--SSPAESKSGKTLPRRDNTRP----------------SKLPKKEAPDSQHHWTAAPGTPSPKQQEQLRYCSGIVKDMFAKKHAAYAWPFYKPVDVDTLGLHDYHDIIKHPMDLSTIKDKLETRQYREAQEFAADVRLMFSNCYKYNPPDHEVVAMARKLQDVFEMRFAKMPDEPEEMLAPAPAPVLHPAPVK------------TQPVMATASSSDTSSDSSSESESSTDD---SEEERAQRLAELQEQLKAVHEQLAALSQPQASKPKKKEKEKKEKK--------------------------------------------------------------------------------------------------------------------KDKHKKKAGVMPALEEILEPPPALKPQGKPKNKDPLPKKSKKLSKKEGGKSNRSMAPPG-------------------------------------------------------------AAPPTLQPVPGLDTEEDLGLTGGAAMAGMAAGEKCKPMSYEEKRQLSLDINKLPGDKLGRVVHIIQSREPS--LKNSNPDEIEIDFETLKPSTLRELERYVSSCLRKK--KKPAVPEKSMEAISAVKTKGTSSDSGSSSESSSSESEDSETGMASKPKKRGR-GEGKKAHHQTTAPGMPLP------QVPLQPQTPALQPSIQLKQQQ--------------PQHPSPAAYMPPP------VTALEPSQLLENPFDPLAHFMHLPHHANDSSSPAPPHLNAHPPGGPVSPETHPFLNQHPILPSPALHNALPQQPSRPSNR-----------AAPLPPKPLQQ--STSQQQPPPQQTLVPPQQLQPQQQQPAPPQQQHLPHHPLHAPQQMRPRPLSPPTLTPQGLLSSQPPQMLLEDDEEPVP---SMSLPMYLQHLQPNRLQATPTSLMQSLQSRPQPPGQPSLLQSVQVQSHLPPPQLPVQTQVQPQQPAPHQPSPQ----LSQHQARHMQQLGFPQGP----------LQTAQTQPGQHKVSMPSTKAQQIIQQQQATQHHSPRQHKADSYNSAHLRDNPSPLMMHSPQIPQYS-LVHQSPSQDKKEPQR------------------------------------------GPSALGGIKEEKLPPSPVMRGEPFSPAMRPESHKHPDSKPTMPGHSQQRADMKPLEMSRPVIRSSEQSGPPPSMQDKEKFKQ----------EPKTPSAPKKVQDVKFKNMGSWASLAQK-------SSTTPSSGLKSSSDSFEQFRRAAREK------EEREKALKAQVEQAEKDRLRKEQEKLR-------------------------------------------------GRDEEDSIEPPRRPLEEPRRRQEPQ----------------------------------------------------------------------------------------------------------------------------------QVQPPPQQHQTQAQAQTLNPAQSPSASQPTQAPPQSPASSQSALDQQ---------------------------------REMARRREQERRRREAMAATIDMNFQSDLMAIFEENLF", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P13709-1", "uniprot_id": "FSH_DROME", "id": "P13709-1", "name": "Homeotic protein female sterile", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSSSEPPPRYEPPVEPVNGIVQPPVIPPAERPGRNTNQLQYLIKTVMKVIWKHHFSWPFQQP---VDAKKLNLPDYHKIIKQPMDMGTIKKRLENNYYWSAKETIQDFNTMFNNCYVYNKPGEDVVVMAQTLEKVFLQKIESMPKEELELEPVTAKGGKKKQRAPATPKSSSGGAGASTGSGTSSAAVTSGPGSGSTKVSVAASSAQQSGLQGATGAGGGSSSTPGTQPGSGAGGAIAARPVSAMGGTVSSTAGGAPSIPPISTMPPHTVPGSTNTTTTAMAGGVGGPGAAGANPNAAALMASLLNAGQTGAYPGAPGQTAVNSSSLLDGSTAAVAAAAAAAAAAAAAAGGAAGAAGGAGTIPAVAVNAANAVQAYVNAGVSVGVDAVIPPQQPAKIKKGVKRKADTTTPTAN--AFESPYTQMDSKSAKIATRRESNRQDLTFQGSGYNMSPLGVSGVPGLGGLVAGGVAGVAVAKNKEKLSDALKSCNEILKELFSKKHSGYAWPFYKPVDAEMLGLHDYHDIIKKPMDLGTVKRKMDNREYKSAPEFAADVRLIFTNCYKYNPPDHDVVAMGRKLQDVFEMRYANIPDEPVANAAHHHGHGHGHGHGHGHGHGHGHGHGHGHGYGGSSSLKHDASDSSSEDSSDTENESNSDEERSARLKMLESKLLGLQEEIRKLSEEASAKKKAKKKLKEKKKSIGGGSGSGSASHHCHATGGGANAGGAGGPGSGGHGSVSVPGGVGSLGPGGAGGANLNALLGGSLVGHGGAAVAGGVPNVGALHSQVHDVAMAFSQMAGGGAAAGAGFGAGVTAAGASSGGKAGTLAGALAAGAAAGAGGTTAGSGSSKGAKSKGGRGAKGSGAGGVGASNNAAAGNAAGGAAGAAAGAGSVGGVGGAGAAGGGNASKRAKGSSSAGAGGGVGGANASAGGAGARGSSKKKPSQVMNFDSEEE---------------DTAKPMSYDEKRQLSLDINKLPGDKLGRVVHIIQNREPS--LRDSNPDEIEIDFETLKPSTLRELESYVASCLRKKTHKKPSGKSKDEQMAEKKQELEKRLQDVTGQLGASKKTAKKDESASSKVEAVQPANPVSSSSSSSDSSSSSSSDSSSSDSSDSEAGDGDERPPRKKKSRDSNGSNVNNPSINVVMGGNLPSGALSPTTMLMGLDHVVNS-NTPTSQMSNMLGNANPLTAAAMLNNNNKTSLPGSNFGGAPAPGNMMHAGAGVPVAGAAVSASTGQQHNKNGPNDLSKVQPGGPINAALPPHSFAGGTATVATSQSSGGIRIASNLHKPSGLGGGDLGEHHAALAAALTSGINSTGTAGGGINNNGGSNNNANPLGGSHGDAMVNASLASLASGLKQIPQFDDPVEQSLASLEFSAGSTGKSGLTDNFLMQQHLMQPAGPQQQQQQQQQQPFGHQQQQQQQQQQQQQQQQHMDYVTELLSKGAENVGGMNGNHLLNFNLDMAAAYQQKHPQQQQQQAHNNGFNVADFGMAGFDGLNMTAASFLDLEPSLQQQQMQQMQLQQQHHQQQQQQTHQQQQ-----------------------------------QHQQQHHQQQQQQQLTQQQLQQQQQQQQQQQHLQQQQHQQQHHQAANKLLIIPKPIESMMPSPPDKQQLQQHQKVLPPQQSPSDMKLHPNAAAAAAVASAQAKLVQTFKANEQNLKNASSWSSLASANSPQSHTSSSSSSSKAKPAMDSFQQFRNKAKERDRLKLLEAAEKEKKNQKEAAEKEQQRKHHKSSSSSLTSAAVAQAAAIAAATAAAAVTLGAAAAAALASSASNPSGGSSSGGAGSTSQQAITGDRDRDRDRERERERSGSGGGQSGNGNNSSNSANSNGPGSAGSGGSGGGGGSGPASAGGPNSGGGGTANSNSGGGGGGGGPALLNAGSNSNSGVGSGGAASSNSNSSVGGIVGSGGPGSNSQGSSGGGGGGPASGGGMGSGAIDYGQQVAVLTQVAANAQAQHVAAAVAAQAILAASPLGAMESGRKSVHDAQPQISRVEDIKASPGGQGQSSPAQQSPQDRAAAKRAEQRRAEQERRRREALAGQIDMNMQSDLMAAFEETL-", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q07442-1", "uniprot_id": "BDF2_YEAST", "id": "Q07442-1", "name": "Bromodomain-containing factor 2", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSRTNMDTRHAHSALLAAPQSATANSRSSNSSSESSSNKNN----INVGVGDDSGNVSAVSIDDGPHFRDIFHYGHEENYKLASSGITNLNSSSHAHQTLSPISISNASTPESFPEHPLGLERETEPALEAEMEAEELPP-----HQSKYLLSSIKATKR-----------------------------------LKDARPFLKPVDPIALN--------------IPHYFNYVQTPMDLSLIETKLQGNVYHSVEQVTSDFKTMVDN------------------------------------------------------------------------------------------CLNFNGPESSISSMAKRIQKYFEKKLSAMPPRVLPASALKKTSRNRKKNEDMDSPLVIRRSVSTTNDNIGESGNREGVSGGRPKR---------------TIHPPKSKDLFDIYENSKPK---SKTLQKKFRTCLKILKVLMSKKNSDINFPFLQPVDPIALNLPNYFDVVKNPMDLGTISNNLMNWKYKTIDQFVDDLNLVFYNCFQFNPEGNEVHSMGKKLKELFNFHWLENQDILNEIETDSD--------------------------LEEDNYSSSYSSDDEYDDEDINE----NDITNPAIQYLEQKLKKMEVELQQLKRQELSKLSKER----KRKHL----------------------------------------------------------------------------------------------------------------------------------------GKTLLRRKAMKHS---------------------------------------------------------------------------------------------------------------------------VDDLKKSITDKINELSDLEMNGMIRIIKNSLPADEILTSNEDEIEIDLDILDEATIARIYERYFEKKNNN-----NSKRK-LSGN-------YSTAPTNK--KKKTLKFLEKDE-------IINNNNYSDSEEDSSD---------------SSDSDSD------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P35817-1", "uniprot_id": "BDF1_YEAST", "id": "P35817-1", "name": "Bromodomain-containing factor 1", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MTDITPVQNDVDVNGNNVNDDVSSNLKRPIDQGDPSNGLAEEENPANNQLHLKKARLDGDALTSSPAGLAENGIEGATLAANGENGYNATGSGAEDEQQGLKKEEGGQGTKQEDLDE-NSKQELPMEVPKEPAPAPPPEPDMNNLPQNPIPKHQQKHALLAIKAVKR-----------------------------------LKDARPFLQPVDPVKLD--------------IPFYFNYIKRPMDLSTIERKLNVGAYEVPEQITEDFNLMVNN------------------------------------------------------------------------------------------SIKFNGPNAGISQMARNIQASFEKHMLNMPAKDAPP----VIAKGRRSSAQEDAPIVIRRAQTHN---------------GRPKR---------------TIHPPKSKDIYP-YESKKPK---SKRLQQAMKFCQSVLKELMAKKHASYNYPFLEPVDPVSMNLPTYFDYVKEPMDLGTIAKKLNDWQYQTMEDFERDVRLVFKNCYTFNPDGTIVNMMGHRLEEVFNSKWAD-RPNLDDYDSDED--------------------------SRTQGDYDDYES--EYSESDIDE----TIITNPAIQYLEEQLARMKVELQQLKKQELEKIRKERRLARGSKKR----------------------------------------------------------------------------------------------------------------------------------------GKRSKGRSGSKNASSKGRRDKKNKLK-----------------------------------------------------------------------------------------------------------TVVTYDMKRIITERINDLPTSKLERAIDIIKKSMPN----ISEDDEVELDLDTLDNHTILTLYNTFFRQYESS-----SGASNGLDGTSGVTRDASSLSPTSAGSRKRRSKALSQEEQSRQIEKIKNKLAILDSASPLSQNGSPGQIQSAAHNGFSSSSDDDVSSESEEE----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . . *: .. : . : . : :: : .. . . :: : ::: : * . .. . * : . . .. .. :. : . : :* . : * . .. :: * ::* :::**:: :** :*** :.* * * :*.***:.*: :: :*: :* *:.*:* **: :** . * *.::*:::*: :: . . .. . .... :: : *:.:* :. :: *.. * :. * * : *: :: **.*. :: : **:. * *: **:*:*:: *. *: : ... . . .. . ", "identical_positions": 55, "similar_positions": 134, "identity": "2.32%" }, { "cls_id": "homologset.agr.MGI:1888525", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q14106-1", "uniprot_id": "TOB2_HUMAN", "id": "Q14106-1", "name": "Protein Tob2", "aln": "MQLEIKVALNFIISYLYNKLPRRRADLFGEELERLLKKKYEGHWYPEKPLKGSGFRCVHIGEMVDPVVELAAKRSGLAVEDVRANVPEELSVWIDPFEVSYQIGEKGAVKVLYLDDSE-GCGAPELDKEIKSSFNPDAQVFVPIGSQDSSLS-------------------NSPSPSFGQSP-------------------------------------------------SPTFIPR-SAQPITFTTASFAATKFGSTKMKKGGGAASGGGVASSGAGGQQPP-QQPRMARSPTNSLLKHKSLSLSMHSLNFITANPAPQSQLSPNAKEFVYNGGGSPS---------------------------------------LFFDAADGQGSGTPGPFGG-----------------------------------------------------SGAGTCNSSSFDMAQVFGG---------------------------------------------------------GANSLFLEKTPFVEGLSYNLNTMQYPSQQFQPVVLAN", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9JM55-1", "uniprot_id": "TOB2_MOUSE", "id": "Q9JM55-1", "name": "Protein Tob2", "aln": "MQLEIKVALNFIISYLYNKLPRRRADLFGEELERLLRKKYEGHWYPEKPLKGSGFRCVHIGEVVDPVVELAAKRSGLAVEDVRANVPEELSVWIDPFEVSYQIGEKGVVKVLYLGDSE-ASGTPELDKEIKSSFNPDAQVFVPIGSQDSSLS-------------------SSPSPSFGQSP-------------------------------------------------SPTFIPR-SAQPITFTTASFAATKFGSTKMKKGGGASGGVSVGGSGAGGQQPPPQQPRMARSPTKNLLKHKSLSLSMHSLNLIPANPAPQSQLSPNAKEFVYNGGGSPS---------------------------------------LFFDGVEGPSTSTTAPFGS-----------------------------------------------------GGASTCNSSSFDVSQVFGG---------------------------------------------------------GANSLFLEKSPFVEGLSYNLNTMQYPNQPFQPVVLAN", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9VXJ9-1", "uniprot_id": "Q9VXJ9_DROME", "id": "Q9VXJ9-1", "name": "", "aln": "MHIEIQVALNFVISYLYNKLPRRRVNIFGEELEKALRDKFQDHWYPEKPFKGSAYRCLKTGDPIDSVLERAARESGVPIGDILENLPNELSVWIDPGEVSFRIGEKGAVKILYTENNENHEDSHSADREVTKMFNPEAQCFRPIDAVNTTMNNMSLSPKGHHQSGSSPHSAASSSPTYKGSPNRTISGSCSSVSGAGSGTGSGSRSGSNHAPGPGTAPGPVPGNGATANAAAAAFMQRGAQAPLTFTTATFAQTKFGSTKLKTSSKRTNSSSAYRMSPTEFSNYIKQRAMQQQMHHGHAVVPSAGSSVSAAYGGMDAVSPARSLSPNPLSLAGNQNQSVSGSSADSYYYPNMPINMYPQYGNPRCLFESHFSADVSSMGLYVSGTAGAAVTAVGSVGANKYSTYLEPCYYGNGHANTQQHSQQQTRVGMDRPNSSESCFGLNVDCGSVVLEDSSSSSSAAAAAVAVTIAGDSSAENSPLSTPTLAAVNVGKATSPPTNSTNNSSSHPIQQQEQPSSSSGNGNGNANANANGNNGNNSNSNTKLIDGISSFYGTGSSYQQLLVAN", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*::**:*****:************.::******: *:.*::.*******:***.:**:: *: :*.*:* **:.**:.: *: *:*:******** ***::*****.**:** :.* .: . *:*:.. ***:** * **.: ::::. *.**:: ** :.:*: * : *:*****:** *******:*... :.. .. .. . :* * :. :. * . *: : :* .****. .:. * . * * *:.... * . : ...*. ..:.:..::: :: .:.* .**. ::: * .:.:: ... :* :::**", "identical_positions": 127, "similar_positions": 131, "identity": "22.52%" }, { "cls_id": "homologset.agr.MGI:1888526", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0ABK0LER7-1", "uniprot_id": "A0ABK0LER7_RAT", "id": "A0ABK0LER7-1", "name": "Exportin-4", "aln": "MRRAQSRAGCPATADRANRPASPGAGCRRSHSSAATGITLVSSQLLRTRRSRQAAEGATPTAAATAPEAREAPGSQRRLAGCGACSHNAAHGASLKRDHDGGGAGAPRSDRSAGERGQSSDGEDAGPGEPRDQWDSGWLSRVRPAVRWAPPSMVSNEQRQHAEHIFLSFRKSKSPFAVCRHILETSKVDYVLFQAATAIMEAVVREWVLLEKGSIESLRTFLLTYVLQRPNLQKYVREQILLAVAVIVKRGSLDKSIDCKSIFHEVSQLISSGNPTVQTLACSILTALLSEFSSSSKTSNIGLSMEFHGNCKRVFQEEDLRQIFMLTVGVLQEFSRRENLSAQMSSVFQRYLALANQVLSWNFLPPNLGRHYIAMFESSQNVLLKPTESWREALLDSRVMELFFTVHRKIREDSDMAQDSLQCLAQLASLHGPIFPDEGSQVDYLAHFIEGLLSTINGIEIEDSEAVGISSIISNLITVFPRNVLTAIPSELFSSFVNCLTHLTCSFGRSAALEEVLDKDDMVYMEAYDKLLESWLTLVQDDKHFHKGFFTQHAVQVFNSYIQCHLAAPDGTRNLTANGVASREEEEISELQEDDRDQFSDQLASVGMLGRIAAEHCMPLLTSLLEERVTRLHGQLQRHQQQLLASPGSSTIDNKMLDDLYEDIHWLILVTGYLLADDTQGETPLIPPEIMEYSIKHSSEVDINTTLQILGSPGEKASSIPGYSRTDSVIRLLSAVLRVSEVESRAIRADLTHLLSPQMGKDIVWFLKRWAKTYLLVDEKLYDQISLPLSTAFGADTEGSQWIIGYLLQKVISNLSVWSSEQDLANDTVQLLVTLVERRERANLVIQCENWWNLAKQFASRSPPLNYLSSPVQRTLMKALVLGGFAHMDTETKQQYWTEVLQPLQQRFLRVINQENFQQMCQQEEVKQEITATLEALCGIAEATQIDNVAILFNFLMDFLNNCIGLMEVYKNTPETVNLIIEVFVEVAHKQICYLGESRAMHLYEACLTLLQVYSKNNLGRQRIDVTAEEEQYQDLLLIMELLTNLLSKEFIDFSDTDEVFRGHEPGQAAGRSVSAADVVLYGVNLILPLMSQDLLKFPTLCNQYYKLITFICEIFPEKIPQLPEDLFKSLMYSLELGMTSMSSEVCQLCLEALTPLAEQCAKAQETESPLFLATRHFLKLVFDMLVLQKHNTEMTTAAGEAFYTLVCLHQAEYSELVETLLSSQQDPIIYQRLADAFNKLTASSTPPTLDRKQKMAFLKSLEEFMANVGGLLCVK", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9ESJ0-1", "uniprot_id": "XPO4_MOUSE", "id": "Q9ESJ0-1", "name": "Exportin-4", "aln": "-----------------------------------------------------------------------------------------------------------------------MMAAALGPPEVIAQLEN------AAKVLMAPPSMVSNEQRQHAEHIFLSFRKSKSPFAVCRHILETSKVDYVLFQAATAIMEAVVREWVLLEKGSIESLRTFLLTYVLQRPNLQKYVREQILLAVAVIVKRGSLDKSIDCKSIFHEVSQLISSGNPTVQTLACSILTALLSEFSSSSKTSNIGLSMEFHGNCKRVFQEEDLRQIFMLTVGVLQEFSRRENLSAQMSSVFQRYLALANQVLSWNFLPPKLGRHYIAMFESSQNVLLKPTESWREALLDSRVMELFFTVHRKIREDSDMAQDSLQCLAQLASLHGPIFPDEGSQVDYLAHFIEGLLNTINGIEIEDSEAVGISSIISNLITVFPRNVLTAIPSELFSSFVNCLTHLTCSFGRSAALEEVLDKDDMVYMEAYDKLLESWLTLVRDDKHFHKGFFTQHAVQVFNSYIQCHLAAPDGTRNLTANGVASREEEEISELQEDDRDQFSDQLASVGMLGRIAAEHCMPLLTSLLEERVTRLHGQLQRHQQQFLASPGSSTIDNKMLDDLYEDIHWLILVTGYLLADDTQGETPLIPPEIMEYSIKHSSEVDINTTLQILGSPGEKASSIPGYSRTDSVIRLLSAVLRVSEVESRAIRADLTHLLSPQMGKDIVWFLKRWAKTYLLVDEKLYDQISLPLSTAFGADTEGSQWIIGYLLQKVISNLSVWSSEQDLANDTVQLLVTLVERRERANLVIQCENWWNLAKQFASRSPPLNFLSSPVQRTLMKALVLGGFAHMDTETKQQYWTEVLQPLQQRFLRVINQENFQQMCQQEEVKQEITATLEALCGIAEATQIDNVAILFNFLMDFLNNCIGLMEVYKNTPETVNLIIEVFVEVAHKQICYLGESKAMHLYEACLTLLQVYSKNNLGRQRIDVTAEEEQYQDLLLIMELLTNLLSKEFIDFSDTDEVFRGHEPGQAAGRSVSAADVVLYGVNLILPLMSQDLLKFPTLCNQYYKLITFICEIFPEKIPQLPEDLFKSLMYSLELGMTSMSSEVCQLCLEALTPLAEQCAKAQETDSPLFLATRHFLKLVFDMLVLQKHNTEMTTAAGEAFYTLVCLHQAEYSELVETLLSSQQDPVIYQRLADAFNKLTASSTPPALDRKQKMAFLKSLEEFMANVGGLLCVK", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9C0E2-1", "uniprot_id": "XPO4_HUMAN", "id": "Q9C0E2-1", "name": "Exportin-4", "aln": "-----------------------------------------------------------------------------------------------------------------------MMAAALGPPEVIAQLEN------AAKVLMAPPSMVNNEQRQHAEHIFLSFRKSKSPFAVCKHILETSKVDYVLFQAATAIMEAVVREWILLEKGSIESLRTFLLTYVLQRPNLQKYVREQILLAVAVIVKRGSLDKSIDCKSIFHEVSQLISSGNPTVQTLACSILTALLSEFSSSSKTSNIGLSMEFHGNCKRVFQEEDLRQIFMLTVEVLQEFSRRENLNAQMSSVFQRYLALANQVLSWNFLPPNLGRHYIAMFESSQNVLLKPTESWRETLLDSRVMELFFTVHRKIREDSDMAQDSLQCLAQLASLHGPIFPDEGSQVDYLAHFIEGLLNTINGIEIEDSEAVGISSIISNLITVFPRNVLTAIPSELFSSFVNCLTHLTCSFGRSAALEEVLDKDDMVYMEAYDKLLESWLTLVQDDKHFHKGFFTQHAVQVFNSYIQCHLAAPDGTRNLTANGVASREEEEISELQEDDRDQFSDQLASVGMLGRIAAEHCIPLLTSLLEERVTRLHGQLQRHQQQLLASPGSSTVDNKMLDDLYEDIHWLILVTGYLLADDTQGETPLIPPEIMEYSIKHSSEVDINTTLQILGSPGEKASSIPGYNRTDSVIRLLSAILRVSEVESRAIRADLTHLLSPQMGKDIVWFLKRWAKTYLLVDEKLYDQISLPFSTAFGADTEGSQWIIGYLLQKVISNLSVWSSEQDLANDTVQLLVTLVERRERANLVIQCENWWNLAKQFASRSPPLNFLSSPVQRTLMKALVLGGFAHMDTETKQQYWTEVLQPLQQRFLRVINQENFQQMCQQEEVKQEITATLEALCGIAEATQIDNVAILFNFLMDFLTNCIGLMEVYKNTPETVNLIIEVFVEVAHKQICYLGESKAMNLYEACLTLLQVYSKNNLGRQRIDVTAEEEQYQDLLLIMELLTNLLSKEFIDFSDTDEVFRGHEPGQAANRSVSAADVVLYGVNLILPLMSQDLLKFPTLCNQYYKLITFICEIFPEKIPQLPEDLFKSLMYSLELGMTSMSSEVCQLCLEALTPLAEQCAKAQETDSPLFLATRHFLKLVFDMLVLQKHNTEMTTAAGEAFYTLVCLHQAEYSELVETLLSSQQDPVIYQRLADAFNKLTASSTPPTLDRKQKMAFLKSLEEFMANVGGLLCVK", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q802D3-1", "uniprot_id": "XPO4_DANRE", "id": "Q802D3-1", "name": "Exportin-4", "aln": "------------------------------------------------------------------------------------------------------------------------MMAAVGAPEVISQLES------AAKVLMAPPSMVSTEQRQHAEHIFLSFRKSKSPFAVCKHILETSKVDYVLFQAATAIMEAVVREWILLEKNSIESLRTFLLTYVLQRPNLQKYVREQILLAVAVIVKRGSLDKSINCKSIFLEVSQLISSGNPTVQTLACSILTALLSEFSSSNKTSNIGLSMEFHGSCKRIFQEDDLRQIFMLTMEVLQEFSRRENLNAQMSCVFQRYLALANQVLSWNFLPPNLGRHYIAMFEATPNVMLKPTESWRESLLDHRVMDLFFTVHRKIREDSDMAQDSLQCLAQLASMQGPIFPDESAQVTYLAHLVEGLLNMINGIEIEDSEAVGISNIISNLISTFSRSVLTALPNVLFASFINCLTLLTCSFGRSAALEEVLDKDDMVYMEAYDKLLESWLTLVQEDEHFPRGCFVQPAVQVFNSYIQCHLAAPDGTRNLTANGVASHEEEEINELQEDDRELFSDQLASIGMLGRIAADHCIPLLTGLLEDRVTRLHGQLQRHQQHLMAAADPDTVDRKVLDDLYEDIHWLILVSGYLLADVPQGETPLIPSEVMEYSIKHSTEVDINTTLQLLGSPGEKATSIPGCNRTDSVIRLLSAVLRTSEVESRATRASLTQLLSPQMGKDIVWFLRRWAKTYLLVDEKLYGQISMPLSTAFGADTEGAQWIVGYLLEKVINNLSVWSSEPELANDTVELLVTLVEKRERANIVVQCENWWSLAKQFASRSPPLHMLSSTVQRTLMKALVLGGFAHMDSDTKQQYWAEVLHPLQQRFLNLINQENFAQICQEVAVKQEIVATLEALCGIAEATQIDNVASLFSFLMDFLSSCIGLMEVYRNSPETVNLIIEVFVEVAHKQICYLGETKSMKLYEVCLTLLQVYSKNNLGRKRLDVAAEEDQYQDLLLIMELLTNLLSKEFIDFSDTDEVLRGQEQSSGAGRAVSAADVVLYGVNIVLPLMSQDLLKFPSLCNQYYKLITFICEIFPEKIPQLPEELFKSLMCSLELGMTSMSSEISQLCLEALSPLAEQCAKTQEKDTPLFIATRHFLKLVFDMLVLQKHNTEMTVAAGEALYTLVCLHQAEYSELVETLLSNQRDALIYQRLADAFNNLTASSTPPTMDRKQKVAFLKSLEEFVANVGGLLCVK", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *. * * :. . * ******..***********************:***************************:****.********************************************:***** *******************************.*************.***:***:*********: ***********.****.********************:**********:: **:*********:*** ***:****************************::*******.:** ****::****. ***************.******:.*.*.****:*. **:**:**** *************************************::*:** :* *.* *****************************:*****.*******: *******:********:**:****.***:**************:::*:....*:*.*:**************:****** .********.*:********:*********:********:**** .***********:**.******* **.**:**************:**************.***:*:**********:***:****:***.******** :******:*******:*****:*:******.************: ***.******************::******:***:*******.:****** *:**: *****.******************* **.******..********:*:************************:::*:***.***************:*:**:***:*****************************:**:* ...*.*:************::************:*************************:****** ************:.*******:********:**.::***:***********************.*****:********************.*:*.:**********:********::*****:*********:**********", "identical_positions": 969, "similar_positions": 144, "identity": "75.94%" }, { "cls_id": "homologset.agr.MGI:1888527", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O70248-1", "uniprot_id": "APBA3_RAT", "id": "O70248-1", "name": "Amyloid-beta A4 precursor protein-binding family A member 3", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MEFLPEPQH--------------------------------------PPG-------PPTMDLEE-------------------------------PKGPEVPSEDHPSNT-----------QWALGPRG--PDTLS-----------EMELDTSSVR------------------------------ALVQQLEALPS-------------------------------------------------------DLGGQFPDGAP--------------------------------------------------CPLHIATGQGLATQ--ENLDAGGLLSAEAGG-------------------------------------------------------------------DNLLGLLRCEAS--------------------LPAQSVPP-------DPAQAAPRLLQPPEDPGGD----PGWMEGT--------------EPADNRSSSSSPELWLETAPL---------VTHRDPPVGTQSQETLASCPAVSEVPGPCGQEE-----------------------------------------------------------------------------------------------------LMDGVLFGAKYLGSTQLLSERNPPPSTRMGQAQEAMDRVK--APEGETQPMTEVDIFISTKRVKVLAADSQDALMDHALQTISYIADIGPVLVLMARRRLAKRTTSQD-RQRQLYKMLCHVFHSEDAQLIAQAIGQAFSIAYSQFLQENRIDPS----QVGMQPSASASHPHNGDLDHFCNSQNCREVCIQKRPGEGLGVALVESGWGSLLPTAVIANLLHGGPAERCGALSIGDRVTAINGTSLVGLSLAACQAAVREVRRHSSVTLSIIHCPPVTTAVIHRPHVREQLGFCVENGIICSLLRGSAAERGGVRVGHRIIEVNGQSVVAMPHARIIQLLTETR-EIHIKTMPAATYRLLTGQEQPVYL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O88888-1", "uniprot_id": "APBA3_MOUSE", "id": "O88888-1", "name": "Amyloid-beta A4 precursor protein-binding family A member 3", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MEFLPGPQH--------------------------------------PPG-------PPTMDLEE-------------------------------PKGPEVPSENHPSNT-----------QSALGPGG--PVTLS-----------EMELDTSSVQ------------------------------ELVQQLEALPS-------------------------------------------------------DLGGPFPDGAP--------------------------------------------------CPLHIATGQGLATQ--ENPDAGGLLSAEAGG-------------------------------------------------------------------DDLLGLLRDEAS--------------------SPAQSVPQ-------DPAQTAPRLLQPPEDPDGD----PGWMEGAS------------AEPADSRSSSSSPEPWLETAPL---------VTQQEPPVGTQSRETLASCPAVTEVPGPCGPEE-----------------------------------------------------------------------------------------------------LMDGVIFGAKYLGSTQLLSERSPAPSTRMGQAQEAMDRVK--APEGETQPMVEVDIFISTKRVKVLAADSQDALMDHALQTISYIADIGPVLVLMARRRLARRTTPQD-RQRRLYKMLCHVFHSEDAQLIAQAIGQAFSIAYSQFLQENRIDPS----QVGTQPSTAASHPHNGDLDHFCNSQNCREVCIQKRPGEGLGVALVESGWGSLLPTAVIANLLHGGPAERCGALSIGDRVTAINGTSLVGLSLAACQAAVREVRRLSSVTLSIIHCPPVTTAVIRRPHVREQLGFCVEDGIICSLLRGGAAERGGVRVGHRIIEVNGQSVVAMPHARIIQLLTETR-EIHIKTMPAATYRLLTGQEQPVYL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O96018-1", "uniprot_id": "APBA3_HUMAN", "id": "O96018-1", "name": "Amyloid-beta A4 precursor protein-binding family A member 3", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MDFPTISRS--------------------------------------PSG-------PPAMDLEG-------------------------------PRDILVPSEDLTPDS-----------QWDPMPGG--PGSLS-----------RMELDESSLQ------------------------------ELVQQFEALPG-------------------------------------------------------DLVGPSPGGAP--------------------------------------------------CPLHIATGHGLASQ--EIADAHGLLSAEAGR-------------------------------------------------------------------DDLLGLLHCEEC--------------------PPSQTGPE-------EPLEPAPRLLQPPEDPDEDSDS-PEWVEGAS------------AEQEGSRSSSSSPEPWLETVPL---------VTPEEPPAGAQSPETLASYPAPQEVPGPCDHED-----------------------------------------------------------------------------------------------------LLDGVIFGARYLGSTQLVSERNPPTSTRMAQAREAMDRVK--APDGETQPMTEVDLFVSTKRIKVLTADSQEAMMDHALHTISYTADIGCVLVLMARRRLARRPAPQD-HGRRLYKMLCHVFYAEDAQLIAQAIGQAFAAAYSQFLRESGIDPS----QVGVHPSPGACHLHNGDLDHFSNSDNCREVHLEKRRGEGLGVALVESGWGSLLPTAVIANLLHGGPAERSGALSIGDRLTAINGTSLVGLPLAACQAAVRETKSQTSVTLSIVHCPPVTTAIIHRPHAREQLGFCVEDGIICSLLRGGIAERGGIRVGHRIIEINGQSVVATPHARIIELLTEAYGEVHIKTMPAATYRLLTGQEQPVYL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9W2S5-1", "uniprot_id": "Q9W2S5_DROME", "id": "Q9W2S5-1", "name": "", "aln": "MVSTTLTTLAAGQTTSSSNHHHHHHHSHQQQQQQQQQDQSQQQPHQQLPYQQRGYYALNGSLELDCDTSNTNSSSSSNNIGYQQHQQQQQQQQQPPLILSQALLSPSPPLNDQISLLFPKCRPKQQQQQQQQQQQQQQQQQQQLQPAQQHQQHVHPTDVNSSCNSNRSSSPTTAGAVGEPLASVSVSPPPPKATPTSSTPSYYKSVNIITQSPPPHSASSHSSESLSSVTPRISTNPFLCAPLTPPTPPHHHHHHHHQQQHQQKQQQPKQQHQTQQQEQQEEDTTGESVVEHSRSGAAGEVLEYPASFYYHTVGDSRRGPGSYTEMPRKRSSALPASNRQQQLHNGNGSQNPFIKENYWEAPPTRASLLLHSPTEYSEEPQQQQQIQQQQQQQQQQQQQQQQQQQQHLHASARRAYHQQREQVYGINQRPQQQQQQNILRVGRSPVNRSFPQQHQQQQQQQQQQQQQQQQQQQPHQQIPTARSNPCADGLTPLASHYLYGSKSSLDQHPGDWEPREQRKLRLREEREREREREREREREREREHLLLEQQQQLQLQEVQVARDNHLSHLAGQQQQQQQRKRHVYGEERERERDRERDMDRDHRLVNGNADPNESWQHLRVTTETLAEEGGKHGKPADKAQHQMHNTNQSQNSDVNVYREHQLDAWKLERSYTLAVESRHGIIEYEGSPRRIGVTTTSNLGATGAAAASAAADESEPPAAAEGAAAATATSQPQQQVPMATVPPLSSTATSLQKTAARAALAALAQSHPHSSHNILSTLLPHSPNPVNPGQMHAAQQSIQNYPVRPGFPQRIISPPSRDPRSSSPPLQQQQYQQQQQQQLQHQQQHFASLMSSHSNNNSNTNKQPLSSDNNAEDTSNDVSEIGTISDLTTPEAVGLSIGIAAGEMASRASTPPQTAQAPPTAVAGSTANGTGSGNGTATGNATAAGSGLGPLSLHTKSSTFDYLYEFSETRKVLEEFFKCPSTDEQPIMENGSDVDSIDIQYEFHSNFERDEEDLAEEEEAEDDEEVDDDADEENDEAEDEDEPLEQDRDQNYRAQAPPQSGHIDSERLVYSGYGQQPQLQAQLTAQPMSGARRHYSGSPLMRDFDFFLDSTSRSSGERDADQDGLNHNQLLSTSSGHGGGVGVSGGLGVGPGGGHNYRYSPETTDYDSNCGDLDSLSGEMNGGVSTSCSNYAKFYASAMPVLEDGLSSGHTSDTENNNNNQKNLQQSTVNQGGQCPTSLSGSTSIGGSGGISMLMDMKRISTNHSLNSMNNQTTTASTTTDSNGGVGGVGHHLVATLVASPNNEQAKSQCQTQLQSHPPKTLSLDQSPSNHSKVFKNIDPELDSLYSIGVFHRPDTVQMTPPPPAPAPHRKPNNNGCSSGVVNTNGSLAGGSNDVDLLQPSSKHTPLAAAISSTLQRSSPTSTITGNGIGNGSGKTRSAGSNCSSSANGGMPPPIPERTNLVSAVQRSPSPGPNSPVWLSRHLDGGAGKDLLESGSDNHSKNHSADEEDVDTDLETDRLLGHQRLDDQGYYDENKSWDRKPRSLLSKISPKQQIPSTKTRNGYNALLSSTPELPPPIPPKGQSGLGLGLTLGAGNGGKLLDLVGGMVQRSLSRSSSEHSEKSLSKMPISGGDLCAGGVDVVASTVAATSATVVASTPALGSPGNGGGSERSAAEMANPGGAVKLSEQEIGTINGGSVMPLGSGSGTGSGAGSGAGSGTGTNAAVVANSNANNNVGGGGGGGNNSSGSGAGSNSNSGEKKVKKSKSKEGGAVLIEGVLFRAKYLGSTQLVCEGQPTKSTRMMQAEEAVSRIKALAPDGDVQPSTEVDLFISTEKIMVLNTDLKEIMMDHALRTISYIADIGDLVVLMARRRFVPQDIDDAPKPNRTPKMICHVFESDEAQFIAQSIGQAFQVAYMEFLKANGIEDHRFVKEMDYQEVLNSQEIFGDELEIFAKKELQKEVVVPKAKGEILGVVIVESGWGSMLPTVVIANLMSSGAAARCGQLNIGDQLIAINGLSLVGLPLSTCQTYIKNTKNQTVVKFTVVPCAPVVEVKIKRPETKYQLGFSVQNGVICSLLRGGIAERGGVRVGHRIIEINNQSVVAVPHEKIVNLLATSVGEILMKTMPTSMFRLLTGQENPIYI", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ::* . * * * : * : * *.. ..:: * * * :** * :* . : ** : * *. :: * ** .* **:*:.. : .* . *:.*. * *** : : * * * :. .:. * ** * : *: : .****. .* *.. *: * ....: * .:** ** . . . * *::**:* *:*******:.* .*. **** **.**:.*:* **:*:.** .***:*:**::: ** :* :: :*****:**** **** ::*******:. : : : .: **:**** :::**:***:***** ** :**: . *: ::. : : . ...:*: *.:.: :** : * ** ***.:*******:***.*****: .*.* *.* *.***:: **** *****.*::**: :::.: : *.:::: *.**. . *:**..: ****.*::*:*******. *****:********:*.***** ** :*::**: : *: :****:: :*******:*:*:", "identical_positions": 236, "similar_positions": 172, "identity": "11.03%" }, { "cls_id": "homologset.agr.MGI:1888530", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P02255-1", "uniprot_id": "H1_DROME", "id": "P02255-1", "name": "Histone H1", "aln": "MSDSAVATSASPVAAPPATVEKKVVQKKASGSAGTKAKKASAT-PSHPPTQQMVDASIKNLKERGGSSLLAIKKYITATYKCDAQKLAPFIKKYLKSAVVNGKLIQTKG--KGASGSFKLSASAKKEKDPKAKSKVLSAEKKVQSKKVASKKIGVSSKKTAVGAADKKPKAKKAVATKKTAEN---------KKTEKAKAKDAKKTGIIKSKPAATKAKVTAAKPKAVVAKASKAKPAVSAKPKKTVKKASVSATAKKPKAKTTAAKK", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q4ABE3-1", "uniprot_id": "Q4ABE3_DROME", "id": "Q4ABE3-1", "name": "", "aln": "MSDSAVATSASPVAAPPATVEKKVVQKKASGSAGTKAKKASAT-PSHPPTQQMVDASIKNLKEHGGSSLLAIKKYITATYKCDAQKLAPFIKKYLKSAVVNGKLIQTKG--KGASGSFKLSASAKKEKDPKAKSKVLSAEKKVQSKKVASKKIGVSSKKTAVGAADKKPKAKKAVATKKTAEN---------KKTEKAKAKDAKKTGIIKSKPAATKAKVTAAKPKAVVAKASKAKPAVSAKPKKTVKKASVSATAKKPKAKTTAAKK", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q4ABD8-1", "uniprot_id": "Q4ABD8_DROME", "id": "Q4ABD8-1", "name": "", "aln": "MSDSAVATSASPVAAPPATVEKKVVQKKASGSAGTKAKKASAT-PSHPPTQQMVDASIKNLEERGGSSLLAIKKYITATYKCDAQKLAPFIKKYLKSAVVNGKLIQTKG--KGASGSFKLSASAKKEKDPKAKSKVLSAEKKVQSKKVASKKIGVSSKKTAVGAADKKPKAKKAVATKKTAEN---------KKTEKAKAKDAKKTGIIKSKPAATKAKVTAAKPKAVVAKASKAKPAVSAKPKKTVKKASVSATAKKPKAKTTAAKK", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q4AB54-1", "uniprot_id": "Q4AB54_DROME", "id": "Q4AB54-1", "name": "", "aln": "MSDSAVATSASPVAAPPATVEKKVVQKKASGSAGTKAKKASAT-PSHPPTQQMVDASIKNLKERGGSSLLAIKKYITATYKCDAQKLAPFIKKYLKSAVVNGKLIQTKG--KGASGSFKLSASAKKEKDPKAKSKVLSAEKKVQSKKVASKKIGVSSKKTAVGAADKKPKAKKAVATKKTAEN---------KKTEKAKAKDAKKTGIIKSKPAATKAKVTAAKPKAVIAKASKAKPAVSAKPKKTVKKASVSATAKKPKAKTTAAKK", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q4AB94-1", "uniprot_id": "Q4AB94_DROME", "id": "Q4AB94-1", "name": "", "aln": "MSDSAVATSASPVAAPPATVEKKVGQKKASGSAGTKAKKASAT-PSHPPTQQMGDASIKNLKERGGSSLLAIKKYITATYKCDAQKLAPFIKKYLKSAVVNGKLIQTKG--KGASGSFKLSASAKKEKDPKAKSKVLSAEKKVQSKKVASKKIGVSSKKTAVGAADKKPKAKKAVATKKTAEN---------KKTEKAKAKDAKKTGIIKSKPAATKAKVTAAKPKAVIAKASKAKPAVSAKPKKTVKKASVSATAKKPKAKTTAAKK", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q07133-1", "uniprot_id": "H1T_MOUSE", "id": "Q07133-1", "name": "Histone H1t", "aln": "MSETAPAASSTLVPAPVEKPSSKRRGKKPG-------LAPARK-PRGFSVSKLIPEALSTSQERAGMSLAALKKALAAAG-YDVEKNNSRIKLALKRLVNKGVLVQTKG--TGASGSFKLSKKAASGNDK-------GKGKKSASAKAKKMGLPRASRSPKSSKT-KAVKKPKATPTKASGSG---------RKTKGAKGVQQRKS------PAKARAANPNSGKAKMVMQKTDLRKAAGRK--------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P06349-1", "uniprot_id": "H1T_RAT", "id": "P06349-1", "name": "Histone H1t", "aln": "MSETAPAASSTLVPAPVEKPATKRRGKKPG-------MATARK-PRGFSVSKLIPEALSMSQERAGMSLAALKKALAAAG-YDVEKNNSRIKLALKRLVNKGVLVQTKG--TGASGSFKLSKKAASGNDK-------GKGKKSASAKAKKLGLSRASRSPKSSKT-KVVKKPKATPTKGSGSR---------RKTKGAKGLQQRKS------PAKARATNSNSGKSKMVMQKTDLRKAAGRK--------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P22492-1", "uniprot_id": "H1T_HUMAN", "id": "P22492-1", "name": "Histone H1t", "aln": "MSETVPAASASAGVAAMEKLPTKKRGRKPAG-----LISASRK-VPNLSVSKLITEALSVSQERVGMSLVALKKALAAAG-YDVEKNNSRIKLSLKSLVNKGILVQTRG--TGASGSFKLSKKVIPKSTR-------SKAKKSVSAKTKKLVLSRDSKSPKTAKTNKRAKKPRATTPKTVRSG---------RKAKGAKGKQQQKS------PVKARASKSK----LTQHHEVNVRKATSKK--------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P53551-1", "uniprot_id": "H1_YEAST", "id": "P53551-1", "name": "Histone H1", "aln": "---MAPKKSTTKTTSKGKKPATSKGKEKSTSKAAIKKTTAKKEEASSKSYRELIIEGLTALKERKGSSRPALKKFIKENY--PIVGSASNFDLYFNNAIKKGVEAGDFEQPKGPAGAVKLAKKKSPEVKKE--KEVSPKPKQAATSVSATASKAKAASTKLAPKKVVKKKSPTVTAKKASSPSSLTYKEMILKSMPQLNDGKGSSRIVLKKYVKDTFSSKLKTSSNFDYLFNSAIKKCVENGELVQPKGPSGIIKLNKKKVKLST---", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . *:: : . .. .*. . . :: .:. :*: * * *:** : . :. :: : :* .*.:*:.**: . *: : . : . * ... * :. : . . : : : .. ", "identical_positions": 16, "similar_positions": 52, "identity": "5.97%" }, { "cls_id": "homologset.agr.MGI:1888594", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9WVM4-1", "uniprot_id": "ICMT_RAT", "id": "Q9WVM4-1", "name": "Protein-S-isoprenylcysteine O-methyltransferase", "aln": "MAGCAARVPPGS-------EARLSLATFLLGASVLALPLLTRAGLQGRT---------GLALYVAGLNALLLLLYRPPRYQIAIRACFLGFVFGCGVLLS-FSQSSWNHFGWYVCSLSLFHYSEYLVTAVNNPKSLSLDSFLLNHSLEYTVAALSSWIEFTLENIFWPELKQITWLSAA------GLLMVIFGECLRKVAMFTAGSNFNHVVQSEKSDTHTLVTSGVYAWCRHPSYVGWFYWSIGTQVMLCNPICGVVYALTVWRFFRDRTEEEEISLIHFFGEEYLDYKKRVPTGLPFIKGVKVGL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9EQK7-1", "uniprot_id": "ICMT_MOUSE", "id": "Q9EQK7-1", "name": "Protein-S-isoprenylcysteine O-methyltransferase", "aln": "MA-AARRGSAGS-------EARLSLATFLLGASVLALPLLTRAGLQGRT---------GLALYVAGLNALLLLLYRPPRYQIAIRACFLGFVFGCGVLLS-FSQSSWNHFGWYVCSLSLFHYSEYLVTAVNNPKSLSLDSFLLNHSLEYTVAALSSWIEFTLENIFWPELKQITWLSAT------GLLMVVFGECLRKAAMFTAGSNFNHVVQSEKSDTHTLVTSGVYAWCRHPSYVGWFYWSIGTQVMLCNPICGVVYALTVWRFFRDRTEEEEISLIHFFGEEYLDYKKRVPTGLPFIKGVKVEL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O60725-1", "uniprot_id": "ICMT_HUMAN", "id": "O60725-1", "name": "Protein-S-isoprenylcysteine O-methyltransferase", "aln": "MAGCAARAPPGS-------EARLSLATFLLGASVLALPLLTRAGLQGRT---------GLALYVAGLNALLLLLYRPPRYQIAIRACFLGFVFGCGTLLS-FSQSSWSHFGWYMCSLSLFHYSEYLVTAVNNPKSLSLDSFLLNHSLEYTVAALSSWLEFTLENIFWPELKQITWLSVT------GLLMVVFGECLRKAAMFTAGSNFNHVVQNEKSDTHTLVTSGVYAWFRHPSYVGWFYWSIGTQVMLCNPICGVSYALTVWRFFRDRTEEEEISLIHFFGEEYLEYKKRVPTGLPFIKGVKVDL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VU37-1", "uniprot_id": "Q9VU37_DROME", "id": "Q9VU37-1", "name": "Protein-S-isoprenylcysteine O-methyltransferase", "aln": "MCAKSRVASPGAGGTSLCSEGRISLYCFLITAALVLIPSVPQN-LYGVVPQVWGAVLWGPFLYYALINMIIRFVLRNHDYQVAIRASFLGFAMAVSVLVICFAPTEWQQFGAYGCFMSLFHYSEFLVIAFANPRTLSLDSFMLNHSVHYGLAAAASWIEFSLEVYYLPQFKRYGYIWVA------GVVLCLLGEMVRKAAIITAGRSFTHLVQNEKHSEHKLITSGIYAYCRHPSYVGWFWWSIGTQIVLLNPICICIYTLVSWLFFHDRIYVEEYSLLNFFQSDYVRYQKRVPTGLPFIRGYLVD-", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P32584-1", "uniprot_id": "STE14_YEAST", "id": "P32584-1", "name": "Protein-S-isoprenylcysteine O-methyltransferase", "aln": "-----------------------------------------------------------MHQDFQEDEHEYPDIRRNPLHEVTMTSYILGILLG--IFVGLFPQIRFKNFNLFIIALSLFHFLEYYITAKYNPLKVHSESFLLNNGKSYMAAHSFAILECLVESFLFPDLKIFSYSLATKLCTVLGCLLVILGQYTRTIAMHTAGHSFSHIVKTKKESDHVLVKTGVYSWSRHPSYLGFFWWAIGTQLLLLNPLSLVIFIFVLWKFFSDRIRVEEKYLIEFFSAEYIEYKNKVGVGIPFI-------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : * ::::: : :**: :. :: *. :.:*. : :****: *: : * ** .: :**:**:. * * : :* :* *::* : .: * :: ::*: *. *: *** .*.*:*:.:* . * *:.:*:*:: *****:*:*:*:****::* **:. : :. * ** ** ** *:.** :*: *:::* .*:*** ", "identical_positions": 70, "similar_positions": 78, "identity": "22.8%" }, { "cls_id": "homologset.agr.MGI:1888669", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "F1LMQ3-1", "uniprot_id": "F1LMQ3_RAT", "id": "F1LMQ3-1", "name": "26S proteasome non-ATPase regulatory subunit 8", "aln": "MFIKGRTAKAPRGEPRRSSRRGQKLAVVAPPPALGSTSRPHFRRESIARRRCRKSGRLFAASRKMAAAAATVNGTTGVSSSGPAATSGGILQAAAGMYEQLKDEWNRKSPNLSKCGEELGRLKLVLLELN-FLPTTG--TKLTKQQLILARDILEIGAQWSILCKDIPSFERYMAQLKCYYFDYKEQLPESAYMHQLLGLNLLFLLSQNRVAEFHTELERLP--AKDIQTNVYIKHPVSLEQYLMEGSYNKVF--LAKGNIPAESYTFFIDILLDTIRDEIAGCIEKAYEKILFAEATRILFFSTPKKMTDYAKKRGWLLGPNNYYS--FASQQQKPEDSTIPSTE----LARQVIEYARQLEMIV", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9CX56-1", "uniprot_id": "PSMD8_MOUSE", "id": "Q9CX56-1", "name": "26S proteasome non-ATPase regulatory subunit 8", "aln": "MFIKGRAAKTPRGEPRRSSRGGRKLAVVAPPPVLGSTSRPHFRRESIARRRCRKSGRRLAASRKMAATAATVNGSTTVSSSGPAATSVGILQAAAGMYEQLKDEWNRKNPNLSKCGEELGRLKLVLLELN-FLPTTG--TKLTKQQLILARDILEIGAQWSILCKDIPSFERYMAQLKCYYFDYKEQLPESAYMHQLLGLNLLFLLSQNRVAEFHTELERLP--AKDIQTNVYIKHPVSLEQYLMEGSYNKVF--LAKGNIPAESYTFFIDILLDTIRDEIAGCIEKAYEKILFAEATRILFFSTPKKMTDYAKKRGWVLGPNNYYS--FASQQQKPEDSTIPSTE----LAKQVIEYARQLEMIV", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P48556-1", "uniprot_id": "PSMD8_HUMAN", "id": "P48556-1", "name": "26S proteasome non-ATPase regulatory subunit 8", "aln": "MFIKGRAPRAPPRERRRATRGG-LRQVVAPPRALGSTSRPHFRRASVCRRRCRKSGGLLAASRKMAAAA--VNGAAGFSSSGPAATSGAVLQAATGMYEQLKGEWNRKSPNLSKCGEELGRLKLVLLELN-FLPTTG--TKLTKQQLILARDILEIGAQWSILRKDIPSFERYMAQLKCYYFDYKEQLPESAYMHQLLGLNLLFLLSQNRVAEFHTELERLP--AKDIQTNVYIKHPVSLEQYLMEGSYNKVF--LAKGNIPAESYTFFIDILLDTIRDEIAGCIEKAYEKILFTEATRILFFNTPKKMTDYAKKRGWVLGPNNYYS--FASQQQKPEDTTIPSTE----LAKQVIEYARQLEMIV", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9V436-1", "uniprot_id": "Q9V436_DROME", "id": "Q9V436-1", "name": "26S proteasome non-ATPase regulatory subunit 8", "aln": "------------------------------------------------------------------------------------------MANVESLYKELTAEWSKRPPNTVKCGQLLDQLKVALVKMA-FLPTDGNDAQSSKKQLILARSVLEVAVEHSVLSKDLLAFERYMAQLKCYYYDYAKIIGESESKYKLLGLNLLYLLSGNRVSDFHTELELLS--VDVIQHNQFIRPILALEQYIMEGRYNKIF--QAKSTVPVEVYSYFMDLLLETVRDEIGACIEKSYDKISAKDAAKRLNLRVPDEIKAFGAKRQWKLEASGDYS--FTDRSVKPKE-LLPSEE----LAEQVLSYARDLEMIV", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P32496-1", "uniprot_id": "RPN12_YEAST", "id": "P32496-1", "name": "26S proteasome regulatory subunit RPN12", "aln": "------------------------------------------------------------------------------------------MPSLAELTKSLSIAFE--NGDYAACEKLLPPIKIELIKNNLLIPDLSIQNDIYLNDLMITKRILEVGALASIQTFNFDSFENYFNQLKPYYFSNNHKLSESDKKSKLISLYLLNLLSQNNTTKFHSELQYLDKHIKNLEDDSLLSYPIKLDRWLMEGSYQKAWDLLQSGSQNISEFDSFTDILKSAIRDEIAKNTELSYDFLPLSNIKALLFFNNEKETEKFALERNWPIVNSKVYFNNQSKEKADYEDEMMHEEDQKTNIIEKAMDYAISIENIV", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : :.*. :. : * : * :*: *:: ::* . . ::*:::: :**:.. *: :: :**.*: *** **:. . : ** :*:.* ** *** *..:.**:**: * . :: : : : *::::*** *:* : ... . : * *:* .::****. * :*: : : * : .: :. :* * : . * :... . :: : . : : .:.:.** .:* **", "identical_positions": 57, "similar_positions": 98, "identity": "15.57%" }, { "cls_id": "homologset.agr.MGI:1888676", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P42677-1", "uniprot_id": "RS27_HUMAN", "id": "P42677-1", "name": "Small ribosomal subunit protein eS27", "aln": "MPLAKDLLHPSPEEEKRKHKKKRLVQSPNSYFMDVKCPGCYKITTVFSHAQTVVLCVGCSTVLCQPTGGKARLTEGCSFRRKQH", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6ZWU9-1", "uniprot_id": "RS27_MOUSE", "id": "Q6ZWU9-1", "name": "Small ribosomal subunit protein eS27", "aln": "MPLAKDLLHPSPEEEKRKHKKKRLVQSPNSYFMDVKCPGCYKITTVFSHAQTVVLCVGCSTVLCQPTGGKARLTEGCSFRRKQH", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P24051-1", "uniprot_id": "RS27L_RAT", "id": "P24051-1", "name": "Small ribosomal subunit protein eS27-like", "aln": "MPLARDLLHPSLEEEKKKHKKKRLVQSPNSYFMDVKCPGCYKITTVFSHAQTVVLCVGCSTVLCQPTGGKARLTEGCSFRRKQH", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9VBU9-1", "uniprot_id": "Q9VBU9_DROME", "id": "Q9VBU9-1", "name": "40S ribosomal protein S27", "aln": "MPLAKDLLHPLPAEEKRKHKLKRLVQHPNSYFMDVKCPGCYRITTVFSHAQGVVVCAGCATILCQPTGGRAKLTEGCSFRRKPQ", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P35997-1", "uniprot_id": "RS27A_YEAST", "id": "P35997-1", "name": "Small ribosomal subunit protein eS27A", "aln": "MVLVQDLLHPTAASEARKHKLKTLVQGPRSYFLDVKCPGCLNITTVFSHAQTAVTCESCSTILCTPTGGKAKLSEGTSFRRK--", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P38711-1", "uniprot_id": "RS27B_YEAST", "id": "P38711-1", "name": "Small ribosomal subunit protein eS27B", "aln": "MVLVQDLLHPTAASEARKHKLKTLVQGPRSYFLDVKCPGCLNITTVFSHAQTAVTCESCSTVLCTPTGGKAKLSEGTSFRRK--", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* *.:***** .* :*** * *** *.***:******* .********* .* * .*:*:** ****:*:*:** ***** ", "identical_positions": 54, "similar_positions": 14, "identity": "64.29%" }, { "cls_id": "homologset.agr.MGI:1888677", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0ABK0LD97-1", "uniprot_id": "A0ABK0LD97_RAT", "id": "A0ABK0LD97-1", "name": "", "aln": "-MAAETLNFGPEWLRALSS--------------------GGSVASPPPSPAMPKYKLADYRYGREEMLALYVKENKVPEELQDKEFAAVLQEEPLQPLALEPLTEDEQRNFSLSVNSVAVLRLMGKGAGPPLAATSRGRGSTRS-RGRGRGDSCFYQRSIEEGDGAFGRNPREIQRSQ-SWDDRGERRFEKSARRDGGMRVLDVVASRVGRQPRWGSQVECGRETGVSYLEALPYLLFVSPVPVRSGFEEGGAGPRKEHARSDSENWRSLREEQEDD--SSWRLGAGPRRDGDRWRSTSPDGGP------------RSAGWREHGE-------------RRRKFDFDLRGERGGCGEEDGRVGGGNSHLRRCRG---------LDGFEDDKDGLPEWCLDDEDEEMGTFDASGAFLPLK-----KGPKEPIPEEQELDFQGLEEEEEE-----PSDGVDEEGPEAGGKEVTPLPPSE-KSSSPSSLP-------ALGPLWTANEDG-EAVEKELPPAEGDEMRG---------LPLSPRISSPPA--------------GPPADLEDEEGLKHLQQEAEKLVASLQDSSLEEEQFT--AAMQTQGLRHSTAATALP----LSHGAARKWFYKDPQGEIQGPFTTQEMAEWFQAGYFSMSLLVKRG-CDEGFQPLGEVIKMWG-RVPFAP-------------------------------GPSPPPLLGNMDQERLKKQQEL-----------------------AAAALYQQLQHQHFLQLVGS----RQLPQCATLREKAAMGDLTPP-------QQQ-LTTFLQQLQALKTPRGGDQNLLPTMSRSLS---------------------------------------------------------------------------------------------------------------------------------------VPDSGPLWDLHTSASSQSGGEASLWDIP------------------------------------------------------------------------------------------------INSSTQGPILEQLQLQHKFQERREVELRVKREEEERKRR---EEKRRQQQQQ-EEQKRRQEEEELFRRKQVRQQELLLKLLQ-----------------------QQQATNVPVPPAPSSPPPLWAGLAKQGLSMKTLLELQMESERQLHKQPAPREPLRAQAPNHRVQLGGLGTAPLNQWVSEAG--------------------------------------------------PLWGGPDKSGGS---------SSGNLGLWEDTL-------------------------------------KSGGSLARSLGLKNSRSSPSLSDSYSHLSGRPVRKKTEE----------------------------EEKLLKLLQGIPRPQDGFTQWCEQMLHTLSTTS-----SLDVPMAVAILKEVESPYDVHDYIR--SCLGDTLEAKEFAKQFLERRAKQKASQQRQQQQQQQQQQQQQQQ-------EAWLSSSSLQTAFQANHSTKLG--PGEGSKAKRR-ALMLHSDPSILGYSLHGPS-----GEIESVDDY", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q99MR1-1", "uniprot_id": "GGYF1_MOUSE", "id": "Q99MR1-1", "name": "GRB10-interacting GYF protein 1", "aln": "-MAAETLNFGPEWLRALSS--------------------GGSVASPPPSPAMPKYKLADYRYGREEMLALYVKENKVPEELQDKEFAAVLQEEPLQPLALEPLTEEEQRNFSLSVNSVAVLRLMGKGAGPPLPATSRGRGSTRS-RGRGRGDSCFYQRSIEEGDGAFGRNPREIQRSQ-SWDDRGERRFEKPARRDG----------------------------------------------VRSGFEEGGAGPRKEHARSDSENWRSLREEQEDD--GSWRLGAGPRRDGDRWRSTSPDGGP------------RSAGWREHGE-------------RRRKFDFDLRGERGGCGEEDGRVGGGNSHLRRCRG---------LDGFEDDKDGLPEWCLEDEDEEMGTFDASGAFLPLK-----KGPKEAIPEEQELDFRGLEEEEEEEE--EPSEGVDEERPEAGGKEATPLPPPE-NSSSPSSLP-------ALGPLWTTNEEGGEAVEKELPPAEGDELRG---------LSLSPRISSPP---------------GPPGDLEDEEGLKHLQQEAEKLVASLQDSSLEEEQFT--AAMQTQGLRHSTAATALP----LSHGAARKWFYKDPQGEIQGPFTTQEMAEWFQAGYFSMSLLVKRG-CDEGFQPLGEVIKMWG-RVPFAP-------------------------------GPSPPPLLGNMDQERLKKQQEL-----------------------AAAALYQQLQHQHFLQLVGS----RQLPQCTTLREKAAMGDLTPP-------QQQQLTTFLQQLQALKTPRGGDQNLLPTMSRSLS---------------------------------------------------------------------------------------------------------------------------------------VPDSGPLWDLHTSASSQSGGEASLWDIP------------------------------------------------------------------------------------------------INSSTQGPILEQLQLQHKFQERREVELRAKREEEERKRR---EEKRRQQQQQQEEQKRRQEEEELFRRKQVRQQELLLKLLQ-----------------------QQQATNVPVPPAPSSPPPLWAGLAKQGLSMKTLLELQMESERQLHKQAAPREPLRAQAPNHRVQLGGLGSAPLNQWVSEAG--------------------------------------------------PLWGGPDKSGGS---------SGGNLGLWEDTL-------------------------------------KSGGSLARSLGLKSSRSSPSLSDSYSHLSGRPVRKKTEE----------------------------EEKLLKLLQGIPRPQDGFTQWCEQMLHTLSTAG-----SLDVPMAVAILKEVESPYDVHDYIR--SCLGDTLEAKEFAKQFLERRAKQKASQQRQQQQQQQQQQQQ----------EAWLSSTSLQTAFQANHSTKLG--PGEGSKAKRR-ALMLHSDPSILGYSLHGPS-----GEIESVDDY", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O75420-1", "uniprot_id": "GGYF1_HUMAN", "id": "O75420-1", "name": "GRB10-interacting GYF protein 1", "aln": "-MAAETLNFGPEWLRALSG--------------------GGSVASPPPSPAMPKYKLADYRYGREEMLALYVKENKVPEELQDKEFAAVLQDEPLQPLALEPLTEEEQRNFSLSVNSVAVLRLMGKGAGPPLAGTSRGRGSTRS-RGRGRGDSCFYQRSIEEGDGAFGRSPREIQRSQ-SWDDRGERRFEKSARRDG----------------------------------------------ARCGFEEGGAGPRKEHARSDSENWRSLREEQEEEEEGSWRLGAGPRRDGDRWRSASPDGGP------------RSAGWREHGE-------------RRRKFEFDLRGDRGGCGEEEGRGGGGSSHLRRCRA---------PEGFEEDKDGLPEWCLDDEDEEMGTFDASGAFLPLK-----KGPKEPIPEEQELDFQGLEEEEEP------SEGLEEEGPEAGGKELTPLPPQEEKSSSPSPLP-------TLGPLWGTNGDGDETAEKE-PPAAEDDIRG---------IQLSPGVGSSA---------------GPPGDLEDDEGLKHLQQEAEKLVASLQDSSLEEEQFT--AAMQTQGLRHSAAATALP----LSHGAARKWFYKDPQGEIQGPFTTQEMAEWFQAGYFSMSLLVKRG-CDEGFQPLGEVIKMWG-RVPFAP-------------------------------GPSPPPLLGNMDQERLKKQQEL-----------------------AAAALYQQLQHQQFLQLVSS----RQLPQCA-LREKAALGDLTPPPPPPPQQQQQQLTAFLQQLQALKPPRGGDQNLLPTMSRSLS---------------------------------------------------------------------------------------------------------------------------------------VPDSGRLWDVHTSASSQSGGEASLWDIP------------------------------------------------------------------------------------------------INSSTQGPILEQLQLQHKFQERREVELRAKREEEERKRR---EEKRRQQQQE--EQKRRQEEEELFRRKHVRQQELLLKLLQ-----------------------QQQA--VPVPPAPSSPPPLWAGLAKQGLSMKTLLELQLEGERQLHKQPPPREPARAQAPNHRVQLGGLGTAPLNQWVSEAG--------------------------------------------------PLWGGPDKSGGG---------SSG-LGLWEDTP-------------------------------------KSGGSLVRGLGLKNSRSSPSLSDSYSHLSGRPIRKKTEE----------------------------EEKLLKLLQGIPRPQDGFTQWCEQMLHTLSATG-----SLDVPMAVAILKEVESPYDVHDYIR--SCLGDTLEAKEFAKQFLERRAKQKASQQRQQQQ------------------EAWLSSASLQTAFQANHSTKLG--PGEGSKAKRR-ALMLHSDPSILGYSLHGSS-----GEIESVDDY", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9Q2B5-1", "uniprot_id": "A0A8M9Q2B5_DANRE", "id": "A0A8M9Q2B5-1", "name": "", "aln": "-MTAETLNFGPEWLRALSS--------------------GSSLSSPPASPAMPKYKLAEYRYGREEMLALYVKDNKVPEEMQDKEFAAILQDEPQQPLALLPLTEEEQRNFSMSVNSVAVLRLMGKGGGAVPAGVNRGRGSVRGGRGRGRGESGFYQRSTEEGEGGFARSVREIHRSQ-SWDDRSERRFEKPLRRDG----------------------------------------------VRVGFEEGAPGVRKEFMRSDSDNWRTLREEQEEE-----DAGETAVSSWRLTVAKREDGGP------------RSAGWREHTGPGE---------VRRRKFDFDFRD-------------GGNEGGRRRAG---------SEGAEDDRDGLPEWCTDEEDGEMGTFDSSGAFMSIK-----KGPKDPILEE---EFQGLEDEEDEGAHQEMKNGMGAEKTEKDVIDSAAVSETEVKLVSPSTPPPPSLPPSLPAPISEAVPSAAPSGLEESPPAPSIPHKLPSEVLSEAMLDLSPSASSSLPSSPPSLSSAATDLPPPGGDIEDDEGMKHLQQEAEKMVAALQDTSLEEECFT--QTLQES----RNTASALP----LSHDSAMKWFYKDPQGEIQGPFSTVEMCEWFQAGYFAMNLLVKRG-CDEGFQPLGEVIKMWG-RVPFAP-------------------------------GPSPPPLLVRN-QAQLHPQPPR-----------------------GATGNMDQERLKKQQELAAATALYQQLQQQ----------------------QQQ------QQLFQLIN-RCGEQGMIPSLNRSMS---------------------------------------------------------------------------------------------------------------------------------------VPDTGSMWDMHTSASQPAGGEASIWDL-------------------------------------------------------------------------------------------------MNSSSQGPILEQLQ---KLQERREAELRAKREEEERKRR---DEKRRE------EQKRR-EEEEHYRRK--QQQDLLMKLLQ-----------------------QAPRQGSSGSGSSWSSGPISG-LGKQSKPLN-LLDVQQEADR-MHKQ------------QHRVQQQRWSDASS--LWGAAG--------------------------------------------------SLDGKVGSSGSS---------SGGGMGVWDEAL-------------------------------------KNQSALRNNMGLKNSRSSPSLSEQYMMRG----RKRTEE----------------------------EDRLLKLLQGMK-SQDGFTTWCEQMLHALNTSANNSSSSQDVPIIVAYLKDLESPYEVLNFIC--SYLGDTVEAKEFARQFLERRAKQKANHQRQQQQLSKEMAGLSMNNFPLQDSVRGMNPSALQSMFQAVHSGKGSGVYDQAAKLKKKQPTMLHSDPSILGYSFHGGPDRYGLNEMEMVEDY", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q7KQM6-1", "uniprot_id": "GGYF1_DROME", "id": "Q7KQM6-1", "name": "GIGYF family protein Gyf", "aln": "--MTDSMKFGPEWLRNMSAEPSGSPSTYNVGNAAQNNSIGGHNLGNNTAASASRNLFPEYRYGREEMLSLFDRNCLLPQILP--SFKKLFVEKVQCPLALTPSSEEDINQNSLGNNSRPAWLQRSP-SGFGSASRGSGRGGTVD-RGRMRGKSAYHP-IYQRPSGLYDESLSVISKAERTWSDRNGTGDSAATTTSTSG----------------------------------------SGALDWNGTPSSSPRKDYSNNHRNLENWRRTRNEDGSGD-GPSSSGSMSGPDIAGWRSGVVGGSTNAGFGTNSHRWGRSTSWRDEDPSVDNAASLQRSISTVATLSTDRTGNNKGSGIGAAEGVGSISHPRLSSSKISQLWTVNNAAGVDADENLPEWAIENPSKLGGSFDASGAFHGDTDLKPIKSSHNTLKTKSLDSYDDVKRPKSKDLS-DPDSGNDITPETSLTKDTNTTAVQEEVESSLSPISSTTTKEVIHGDISDRIKEVADEVEKLIMDDDHKISSNQSQHQNHDGFTAALPRMADIEIN-----------VKPSVTAVHRQAPSTMPIQITPTITDVAPPSHAVVSFSDHETMQHHNMHHLPQFPMIPTPHIITPNLNELWFYRDPQANVQGPFSAVEMTEWYRAGYFNENLFVRRY-SDNRFRPLGELIKFCHGNMPFTHSHLLPSPIELENIPVGQIPAPLTASLSITPHKPSPIPIALSVVEQQLQQQRDEQLKANVTATAEALRAAIKGSFGGNSIGNTSHLLTMRFQMLQDQYIQHQEYQILAELSKNECFQRLSAVEQETVVRRKVQLLGLPEYLISLNGLSNSLSVLNPVAGRQLYRAVVEHAKKDQQHIFANTEQQRSVGNLLDANNFILNAQIMIQQSQQEVGPLVSSVDCIMQGGTAADLNKPNEIPRNELDLINEYNLRMLLRGQPTSTQQQPPALTNSATENLPGVDFLTETQLLERQNLMIPIWLPPNNNKQQETDQQWAEMSNADASLWETANLNEERNEDQQLLIQKSSEACFADTEKDVKIAQLFQVQSGNVVNHTALEELDQSPQNLKGSHNQKIVKSLVSDIQQNHNEELNSHQHQVKQANKQNLNTKQNAAQSALKPINNENDRKREQTEEKKRQREERKRQQLEDDKRRALNESEEQTRQIQEEKERQQQIQAQRRKALLGNVHSLSVQNGMSGTLASAQSKKNDDAKTAEPQVSSRLPSTSVAPWSFQLQNSMRSAPGLAEIQKAERRERRADQQRHQELLDKQLRANAAAAAEANDALLKWQSTPASAPVMSLAEIQAEEARRLANDLVDRQRRRELEHHQQAPLSSAVLVTSATSNIWGNANKAWSSSAAQSLSLKTSSGTGLWDEPNPLGSNGSGTSGTSSVTAAAVLAGGLNSANKSTLQAQNKSSALFASPRNLRKSQTLPALSNPEKSNKNGPGQRPEKQKLAQTRSKGAAVSIEEKDRERKLNAKSQQSSTDQAISKVNEYENEFTSWCIKSLDNMSAKV-------DVPTFVAFLQDLEAPYEVKDYVR--IYLGDGKDSLDFAKQFLERRSKYKSLQRAQKAHN-----------------DDMCKPAPAITPSANDYADSKN----KQKKIKKN--KMTKMDARILGFSVTAAEGRINVGIRDYVEGP", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P32909-1", "uniprot_id": "SMY2_YEAST", "id": "P32909-1", "name": "Protein SMY2", "aln": "-------MIAPDSQRLFGS-----------------------------------------------------------------------FDEQFKDLKLDSVDTENNNTHGVSTILD----------SSPASVNNNTNGAVAASVNTVPGSTFRSNTPLLGGRHPLSRTSSLIDSIG---------------------------------------------------------------------------------IQRAASPFSSMKEPFIPQ-----SSGVMSSSFWHGDHPESRVSTP-----------------------------------------------------------------------------------------VQQHPLLQRNESSSSFS-YAANLGVN-----------------------------------------LSTHSLAVDITPLSTPTAAQSHVNLFP--------------------------------------------------------------------------SSDIPPNMSMNGMSQLPAPVSVESS------------------------------------------WRYIDTQGQIHGPFTTQMMSQWYIGGYFASTLQISRLGSTPETLGINDIFITLGELMTKLEK-----------------------------YDTDPFTTFDKLHVQTTSSDSIN----------------------LNLAPYASGVAATGTIKATEN---------------------------------DIFKPLTHDNIWDMDGGTTSKGVDIKLASATTIS--------------------------------------------------------------------------------------------------------------------------------------QTDESHKQEYKSTTMLEKGK---------------------------------------------------------------------------------------------------------KEKSESVAKALLDEQEKRNRELKRKEEARLSKKQKQKE---DDLLKKQKEQKEQKEKEALEAEKQKKSEKTKKDTQTQTEG----------------------FKTSKDLPSLNSSSANPAPWASKVKVNNAIETSIKNGVSSTGKKKGEPLGLQQRNSKEEKQKEELKSVLNWANKSSLPSNQT-------------------------------------------------IDIKSQFQKSPKG-------MKESSPLKELEDPN-----------------------------------FIEEQKKLWEKVQSSSKQVKSTSSASTTTSSWTTVTSKGK------------------------------APIGTVVSPYSKTNTSLNSSLTAKTSTTSTTT-----------TFASMNNVSPRQEFIKWCKSQMKLNSGITNNNVLELLLSLPTGPESKELIQETIYAN---------------SDVMDGRRFATEFIKRRVACEK----QGDDPLSWNEALALSGNDDDGWEFQVVS------KKKGRKH-", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "Q02875-1", "uniprot_id": "SYH1_YEAST", "id": "Q02875-1", "name": "SMY2 homolog 2", "aln": "MNPINSLAFDLHSVKLADAN--------------------------------------------SDTAALSNSNTPTMNNAALLQRPSSIMDSIGVQRVPSPFVPGSNAISGASTVPFNAYDAEITGSPLQISANQENNSAFSAASSNLHMNASSPSVLNKPSSTFPNVAPYLYNATG------------------------------------------------------------------------------PAPNVGNQPPPPGIESQWKYID----SNGNIQGPFGTNNMSQWYQGGY----------------------------------------------------------------------------------------FTPTLQICRLATSPEPFGVNDRFIRLG----------------------------------------ELTTLVNNYQDPFVAFDFIVIRALNAVP----------------------------------------------------------------------LVAPTSSEKQKVESRDLIPVADVHSDDFTYEEILGLKFE-------DGSYYHETQVWVP--------VDGRHITKVDRIPKISAYTAPLSTTSSRSNKTTSSHEEKVPSHEEASPEEQEVFSEEGRTVSNITN-----------------------------EEESIVKNPTKQEEESRGSEKEQ-------------------NILDQVQPEIEEVDRKDVISTADEP------------------------------KSKDTPQMTSEEQKRFAKAELMAQKLLEEQQRQEEEKK------------------------------------------------------------------------------------------------------------------------------------RREEQRKLKKEKKLKQKQKKEEEKLK---------------------------------------------------------------------------------------------------KKKKEEGKLEKEKQKELLNNILTGDTETPSSENTATSITTNLAPWANKKPEGAVYNQISSALEDLKKENSSKKEKKPNRTQLD----------------REQALKLQKEILSSAQIPKTQTGSAWGIKPQQPIKVDIKGELMKDSTKINSQSKINKANNGDIKPDSTFIEEQKKLWEQVQKKTKKFN---------------------------------------------RASSLDDFISRTPSP---------SSSALNSSNTSN-------------------------------------AWTTVSSKSTTHIASTMPVAGNQSKSYISLDTLRSSGG----------------------------LSTATKTKMSDKSKQIGSSTSIPTLKARQVKPSR---------IPAYPGNASVSKRQEFLRWCRSQLKLNTGVQPDNVLEMLLSLPPGSESKEIIADTIYSY---------------SSTMDGRRFATDFIKKRLECEE----EINDPLSWSEVLAMPEGSSEDWEFQVVG------KKKGKRF-", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . : .. :. . . . . . ... . .: .. * . . .*. : . . . : : ..::: .. . ::: :. . : . . : : : . . : . : :. . ..: .: * :: ::. : . . . : . : : . : .. : . . : . :. . .. . .:. :. : *. :. . :*. . :: . . . : : . : .:.. . ", "identical_positions": 5, "similar_positions": 118, "identity": "0.3%" }, { "cls_id": "homologset.agr.MGI:1888678", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D4A1F5-1", "uniprot_id": "D4A1F5_RAT", "id": "D4A1F5-1", "name": "", "aln": "MARILILLLGGLVALCAGHGMFMDKLSSKKLCADEECVYTISLARAQEDYNAPDCRFINVKKGQQIYVYSKLVTENGAGAFWAGSVYGDHQDEMGIVGYFPSNLVREQRVYQEATKEIPTTDIDFFCE", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9JIE3-1", "uniprot_id": "OTOR_MOUSE", "id": "Q9JIE3-1", "name": "Otoraplin", "aln": "MARILILLLGGLVVLCAGHGVFMDKLSSKKLCADEECVYTISLARAQEDYNAPDCRFIDVKKGQQIYVYSKLVTENGAGEFWAGSVYGDHQDEMGIVGYFPSNLVKEQRVYQEATKEIPTTDIDFFCE", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9NRC9-1", "uniprot_id": "OTOR_HUMAN", "id": "Q9NRC9-1", "name": "Otoraplin", "aln": "MARILLLFLPGLVAVCAVHGIFMDRLASKKLCADDECVYTISLASAQEDYNAPDCRFINVKKGQQIYVYSKLVKENGAGEFWAGSVYGDGQDEMGVVGYFPRNLVKEQRVYQEATKEVPTTDIDFFCE", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*****:*:* ***.:** **:***:*:*******:********* *************:**************.***** ********* *****:***** ***:***********:**********", "identical_positions": 109, "similar_positions": 13, "identity": "85.16%" }, { "cls_id": "homologset.agr.MGI:1888697", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q5BKE0-1", "uniprot_id": "TAF9_RAT", "id": "Q5BKE0-1", "name": "Transcription initiation factor TFIID subunit 9", "aln": "-----------MESGK------MASPKSMPKDAQMMAQILKDMGITEYEPRVINQMLEFAFRYVTTILDDAKIYSSHAKKPT-----VDADDVRLAIQCRADQSFTSPPPRDFLLDIARQRNQTPLPLIKPYSGPRLPPDRYCLTAPNYRLKSLQK----KAPTPAGRITVPRLSVGSVSSRPSTPTLGTPTPQAMSVSTKVGTPMSLTGQRFTVQMPASQS---PAVKASIPATPAVQNVLINPSLIGSKNILITTNMVS-QNTANESANALKRKREEEDDDDDDDDDD-YDNL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8VI33-1", "uniprot_id": "TAF9_MOUSE", "id": "Q8VI33-1", "name": "Transcription initiation factor TFIID subunit 9", "aln": "-----------MESGK------MASPKSMPKDAQMMAQILKDMGITEYEPRVINQMLEFAFRYVTTILDDAKIYSSHAKKAT-----VDADDVRLAIQCRADQSFTSPPPRDFLLDIARQRNQTPLPLIKPYSGPRLPPDRYCLTAPNYRLKSLQK----KAPAPAGRITVPRLSVGSVSSRPSTPTLGTPTPQTMSVSTKVGTPMSLTGQRFTVQMPASQS---PAVKASIPATSTVQNVLINPSLIGSKNILITTNMVS-QNTA-ESANALKRKREDDDDDDDDDDDDDYDNM", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q16594-1", "uniprot_id": "TAF9_HUMAN", "id": "Q16594-1", "name": "Transcription initiation factor TFIID subunit 9", "aln": "-----------MESGK------TASPKSMPKDAQMMAQILKDMGITEYEPRVINQMLEFAFRYVTTILDDAKIYSSHAKKAT-----VDADDVRLAIQCRADQSFTSPPPRDFLLDIARQRNQTPLPLIKPYSGPRLPPDRYCLTAPNYRLKSLQK----KASTSAGRITVPRLSVGSVTSRPSTPTLGTPTPQTMSVSTKVGTPMSLTGQRFTVQMPTSQS---PAVKASIPATSAVQNVLINPSLIGSKNILITTNMMSSQNTANESSNALKRKRE--DDDDDDDDDDDYDNL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q27272-1", "uniprot_id": "TAF9_DROME", "id": "Q27272-1", "name": "Transcription initiation factor TFIID subunit 9", "aln": "-----------MSAEKSDKAKISAQIKHVPKDAQVIMSILKELNVQEYEPRVVNQLLEFTFRYVTCILDDAKVYANHARKKT-----IDLDDVRLATEVTLDKSFTGPLERHVLAKVADVRNSMPLPPIKPHCGLRLPPDRYCLTGVNYKLRATNQPKKMTKSAVEGRPLKTVVKPVSSANGPKRPHSVVAKQQVVTIPKPVIKFTTTTTTKTVGSSGGSGGGGGQEVKSESTGAGGDLKMEVDSDAAAVGSIAGASGSGAGSASGGGGGGGSSGVGVAVKREREEEEFEFVTN-", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q05027-1", "uniprot_id": "TAF9_YEAST", "id": "Q05027-1", "name": "SAGA complex/transcription factor TFIID complex subunit TAF9", "aln": "MNGGGKNVLNKNSVGSVSEVGPDSTQEETPRDVRLLHLLLASQSIHQYEDQVPLQLMDFAHRYTQGVLKDALVYNDYAGSGNSAGSGLGVEDIRLAIAARTQYQFKPTAPKELMLQLAAERNKKALPQVMGTWGVRLPPEKYCLTAKEWDLEDPKSM------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . . : : *:*.::: :* . .: :** :* *:::*:.**. :*.** :* .:* . . :. :*:*** : .*. . :..: .:* **. .** : * ****::****. :: *. :. ", "identical_positions": 35, "similar_positions": 53, "identity": "11.86%" }, { "cls_id": "homologset.agr.MGI:1888707", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8VIB3-1", "uniprot_id": "SIA10_MOUSE", "id": "Q8VIB3-1", "name": "Type 2 lactosamine alpha-2,3-sialyltransferase", "aln": "MKGYLVAIFLSSIFLYYVLYCILWGTNGYWFPAEEMRTRNNVNNCFKKPAFANLLRFPQLYPFLCRADFIKVAAMSGTNNFPLPYGIKTFETYFSSALSKLQSCDLFDEFDRVPCKRCVVVGNGGVLKNKTLGATIDSYDVIIRMNNGPVLGHEEEVGTRTTFRLFYPESVFSDSSHYDPNTTAVLVVFKPQDLRWLVEILLGKKINTQGFWKTPALKLIYKQYQIRILDPYITSEAAFQMLRFPRVFPKDQKPKHPTTGIIAITMAFHICSEVHLAGFKYNFYSPNSPLHYYGNATMSLMKQNAYHNLTAEQLFLNDIIKKKMVINLT--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P61943-1", "uniprot_id": "SIA10_RAT", "id": "P61943-1", "name": "Type 2 lactosamine alpha-2,3-sialyltransferase", "aln": "MKGYVVAIFLSSIFLYYVLYCILWGTNGYWFPNEEMKSKNNVKNCFKKPAFASLLRFPQFYPFLCKADFVKVAATYGTNNFLLPYGVKTFESYFRSGLSKLQSCDLVGQFDTVPCKRCVVVGNGGVLKNKTLGAKIDSYDVIIRMNNGPVLGHEEEVGKRTTFRLFYPESVFSDPSHYDPNTTAVLVVFKPQDLRWLMEILIGKKINTDGFWKKPALKLIYKQYQIRILDPYIIREAAFQLLRFPRVFPKDQKPKHPTTGIIALTLAFHICSEVHLAGFKYNFYTPDSPLHYYGNATMSLMKKNAYHNLTAEQLFLKNLIKKKMVINLTQN", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9Y274-1", "uniprot_id": "SIA10_HUMAN", "id": "Q9Y274-1", "name": "Type 2 lactosamine alpha-2,3-sialyltransferase", "aln": "MRGYLVAIFLSAVFLYYVLHCILWGTNVYWVAPVEMKRRNKIQPCLSKPAFASLLRFHQFHPFLCAADFRKIASLYGSDKFDLPYGMRTSAEYFRLALSKLQSCDLFDEFDNIPCKKCVVVGNGGVLKNKTLGEKIDSYDVIIRMNNGPVLGHEEEVGRRTTFRLFYPESVFSDPIHNDPNTTVILTAFKPHDLRWLLELLMGDKINTNGFWKKPALNLIYKPYQIRILDPFIIRTAAYELLHFPKVFPKNQKPKHPTTGIIAITLAFYICHEVHLAGFKYNFSDLKSPLHYYGNATMSLMNKNAYHNVTAEQLFLKDIIEKNLVINLTQD", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*:**:******::******:******* **.. **: :*::: *:.*****.**** *::**** *** *:*: *:::* ****::* ** .*********..:** :***:**************** .*********************** ***************. * *****.:*..***:*****:*:*:*.****:****.***:**** ********:* **:::*:**:****:************:*:**:** *********** .**************::*****:*******:::*:*::***** ", "identical_positions": 236, "similar_positions": 64, "identity": "71.3%" }, { "cls_id": "homologset.agr.MGI:1888711", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9Z126-1", "uniprot_id": "PLF4_MOUSE", "id": "Q9Z126-1", "name": "Platelet factor 4", "aln": "MSVAAVFRGLRPS-PELLLLGLLFLPAVVAVTSAGPEESDGDLSCVCVKTISSGIHLKHITSLEVIKAGRHCAVPQLIATLKNGRKICLDRQAPLYKKVIKKILES", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P06765-1", "uniprot_id": "PLF4_RAT", "id": "P06765-1", "name": "Platelet factor 4", "aln": "MSAAAVFRGLRPS-PELLLLGLLLLPAVVAVTRASPEESDGDLSCVCVKTSSSRIHLKRITSLEVIKAGPHCAVPQLIATLKNGSKICLDRQVPLYKKIIKKLLES", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P02776-1", "uniprot_id": "PLF4_HUMAN", "id": "P02776-1", "name": "Platelet factor 4", "aln": "MSSAAG---FCASRPGLLFLGLLLLPLVVAFASAEAEE-DGDLQCLCVKT-TSQVRPRHITSLEVIKAGPHCPTAQLIATLKNGRKICLDLQAPLYKKIIKKLLES", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P10720-1", "uniprot_id": "PF4V_HUMAN", "id": "P10720-1", "name": "Platelet factor 4 variant", "aln": "MSSAARSRLTRATRQEMLFLALLLLPVVVAFARAEAEE-DGDLQCLCVKT-TSQVRPRHITSLEVIKAGPHCPTAQLIATLKNGRKICLDLQALLYKKIIKEHLES", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "** ** .: :*:*.**:** ***.: * .** ****.*:**** :* :: ::********** **...********* ***** *. ****:**: ***", "identical_positions": 62, "similar_positions": 22, "identity": "58.49%" }, { "cls_id": "homologset.agr.MGI:1888742", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZLU1-1", "uniprot_id": "D3ZLU1_RAT", "id": "D3ZLU1-1", "name": "Exostosin-like 1", "aln": "-MLWRR-KSFWLALSAFWLLLILLGVFP-LRLAVSPRPLPGRSQGWPRWLDATFLQSFSQPETNPEEDVQQLPRVS----------RGSSCTWGACFDTSKCRGK-VLKIFVHSAAG--------PTTEAQRRILDSLEGSRYYALSPAEACLLLF---------LPSQDRRGACGPLP--PNWNGGRNHLVLSLYP------APCTR---LGQAMVAEASPSLDIFRPGFDVALPYLPEAHPLKGGAPGSLQRHGPQPG-ATLVAVAEERGRWRITTTHA---------------SACPW--------DRNCEQDPGPQQTYP-GEILPNVTFCLIPGHR-SATSCFLQALQAGCIPVLLSPRWELPFSEVIDWTKAAIVADERLPLQVLAALREMLPSRVLALRQQTQFLWTAYFSSVEKVVHTTLEIIQDRIWGASAHPSLMWNSPPGALLALPTFSTSLQDFPFYHLQLGSSPGSSFSAVIWVGV-----SEESPPKLIQEVAGSRHCAQILILWNSEKPPP--DRWPKTA-VPLTVI------------------EGHRKVSDRFFLYSNISTNVILSLDAQSTLSTSEVDFAFVVWQSFPERMVGFVTWSHFWDEARQGWGYSAEMANEFSMVLTTAAFYHRYYHTLFTHSLPKALRSIADETPTCVDILMNFLVATVTKLPPIKVPYSRQHQEAAP--MASEGPRPVPEPQALDQDCINRLAAGLGHMPLVSSRVRLDPVLFKDPVSVQRKKYRSLEKP--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9JKV7-1", "uniprot_id": "EXTL1_MOUSE", "id": "Q9JKV7-1", "name": "Exostosin-like 1", "aln": "-MLWRR-KSFWLALSAFWLLLVLLGVFP-LRLAVLPGPLPGRSQGWPRWLDAAFLQSFSQSETNPE-DVAQLPRVS----------RGSSCTWGACFDTSKCRGK-VLKIFVHSPAG--------PTSEAQRRILDSLEGSRYSALSPADACLLLF---------LPSQDRRGACGPLP--PNWNGGRNHLVLSLYP------APCTR---LGQAMVAEASPSSDIFRPGFDLALPYLPEAHPLRGGAPGKLQQHSPQPG-ATLLAVAEEKGRWRITSTHA---------------SACLW--------DRHCEQDPGPQQTYP-GETLPNATFCLIPGHR-SATSCFLQALQAGCIPVLLSPRWELPFSEVIDWTKAAIIADERLPLQVLAALREMLPSRVLALRQQTQFLWTAYFSSVEKVIHTTLEIIQDRIWGASGHPSLMWNSPPGALLALPTFSTSLQDFPFYHLQLGSGPGSSFSAVIWVGA-----SGESLLKLIQEVAGSRHCAQILILWNSEKLPP--DRWPETA-VPLTVI------------------KGHRKVSNRFFPYSNISTNVILSLDAQSTLSTSEVDFAFVVWQSFPERMVGFLSGSHFWDEAQGGWGYRTGMTNEFSMVLTTAAFYHRYYHTLFTHSLPKALRTIADETPTCVDVLMNFLVATVTKLPPIKVPYGRQHPEAVP--MDSGDPRPVPEPQPLDQDCINRLAAGFGHMPLVSSQVRLDPVLFKDPVSVQRKKYRSLEKP--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q92935-1", "uniprot_id": "EXTL1_HUMAN", "id": "Q92935-1", "name": "Exostosin-like 1", "aln": "MQSWRRRKSLWLALSASWLLLVLLGGFSLLRLALPPRPRPGASQGWPRWLDAELLQSFSQPGELPE-DAVSPPQAP----------HGGSCNWESCFDTSKCRGD-GLKVFVYPAVG--------TISETHRRILASIEGSRFYTFSPAGACLLLL---------LSLDAQTGECSSMP--LQWNRGRNHLVLRLHP------APCPRTFQLGQAMVAEASPTVDSFRPGFDVALPFLPEAHPLRGGAPGQLRQHSPQPG-VALLALEEERGGWRTADTGS---------------SACPW--------DGRCEQDPGPGQTQR-QETLPNATFCLISGHRPEAASRFLQALQAGCIPVLLSPRWELPFSEVIDWTKAAIVADERLPLQVLAALQEMSPARVLALRQQTQFLWDAYFSSVEKVIHTTLEVIQDRIFGTSAHPSLLWNSPPGALLALSTFSTSPQDFPFYYLQQGSRPEGRFSALIWVGP-----PGQPPLKLIQAVAGSQHCAQILVLWSNERPLP--SRWPETA-VPLTVI------------------DGHRKVSDRFYPYSTIRTDAILSLDARSSLSTSEVDFAFLVWQSFPERMVGFLTSSHFWDEAHGGWGYTAERTNEFSMVLTTAAFYHRYYHTLFTHSLPKALRTLADEAPTCVDVLMNFIVAAVTKLPPIKVPYGKQRQEAAP--LAPGGPGPRPKPPAPAPDCINQIAAAFGHMPLLSSRLRLDPVLFKDPVSVQRKKYRSLEKP--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9V730-1", "uniprot_id": "EXT1_DROME", "id": "Q9V730-1", "name": "Exostosin-1", "aln": "-MQAKKRYILV-FVSCAFLAYAYFGGYRLKVSPLRPRRAQHESAKDGGVQPHEQLPSFLGAHDMQELQLLQSNQSKSLDSSKHLVTRKPDCRMETCFDFTRCYDR--FLVYIYPPEPLNSLGAAPPTSANYQKILTAIQESRYYTSDPTAACLFVLGIDTLDRDSLSEDYVRNVPSRLARLPYWNNGRNHIIFNLYSGTWPDYAENSLGFDAGEAILAKASMGVLQLRHGFDVSIPLFHKQFPLRAGATGTVQSNNFPANKKYLLAFKGKRYVHGIGSETRNSLFHLHNGRDMVLVTTCRHGKSWRELQDNRCDEDNREYDRYDYETLLQNSTFCLVPRGRRLGSFRFLEALQAGCIPVLLSNAWVLPFESKIDWKQAAIWADERLLLQVPDIVRSIPAERIFALRQQTQVLWERYFGSIEKIVFTTFEIIRERLPDYPVRSSLVWNSSPGALLTLPTFADSSRYMPFLLNSMGAEPRHNYTAVIYVQIGAALGPNAALYKLVRTITKSQFVERILVLWAADRPLPLKKRWPPTSHIPLHVISLGGSTRSQGAGPTSQTTEGRPSISQRFLPYDEIQTDAVLSLDEDAILNTDELDFAYTVWRDFPERIVGYPARAHFWDDSKNAWGYTSKWTNYYSIVLTGAAFYHRYYNYLYTNWLSLLLLKTVQQSSNCEDILMNLLVSHVTRKPPIKVTQRKGYKDRE----TGRSPWNDPDHFIQRQSCLNTFAAVFGYMPLIRSNLRMDPMLYRDPVSNLRKKYRQIELVGS", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q5IGR6-1", "uniprot_id": "EXT1C_DANRE", "id": "Q5IGR6-1", "name": "Exostosin-1c", "aln": "-MQARKKYVLLGLCTCCWILLYYWAGLQERLLGLITHRRGEVPRPWPDWLDRALLPNFAEQLDLQNGGGP-GDSPRQRKQAWSSIYKDSRCRMDTCFDFGRCQTQSGFRVYIYPPE------KGERVSEGYRKILTSVSESRYYTSDPREACLFVLGIDTLDRDQLSQQFVPNVDERIRGYPLWNDGRNHVIFNLYSGTWPNYTED-LGFNVGQAILAKASLNTEHFRPGFDISIPLFSKEHPQKGGKRGWLVRNSVPPRRKYLLMFKGKRYLTGIGSDTRNALHHIHNGKDIVSLTTCRHGKDWEKHKDARCDHDNQEYERFDYQELLHNSTFCLVPRGRRLGSFRFLESLQAACIPVLLSNGWELPFSDVIQWNQAVVEGDERLLLQVPSTVRAVGIDRVLALRQQTQTLWDAYFSSVDKIVLTTLEIIKDRVYSHISRNKLMWNALPGGLLVLPEFSTHLAHYPFYYLHLGISPGLEFTAVIHATS-PLVSQSQPIMKLLQVVSKSKYCSQIIILWNSEKSPPQRSKWPPMP-VPLTVT------------------DGRRKTSSRFLPHAAIETEAVLSLDEDTVLLTSEINFAFHVWRSFPDRIVGYPPRSHFWDPVKKAWGYTSKWTNEYSIILTGAAFYHRYYHHLFSHYLPSSLRALVDHSCNCEDILMNFLVSSVAHLPPVKVAQRKQYKEMPSLQGTKMAPWANPEHFTQRQECVNTFSSWFGYMPLEHSQFRLDPVLFKDHVSVLRKRYKDLERV--", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :: : :. :: . : . . * .* : : * :*** :* : ::::.. : ::** ::. **: : .* ***::: *. : . : ** ****::: *:. : *:*::*:** :* ***:::* : : .* :.* * : :. . *: . :: ::* * .*:.* : * * ****:. * .: **::***.******* * ***.. *:*.:*.: .**** *** :: : *::******* ** **.*::*:: **:*:*::*: . : .*:**: **.**.*. *: ** * * ::*:* . . **:: :: *:. :*::** :: * .:** . :** * .*: . *.** : * *:.:**** : * *.*::**: **:.**:*:**: . :**** : .*** : :* :*::** ********: *::: *. * .:.: .* *:***::*: *:: **:**. : : * *. .*:* ::: :*:*** *..*:**:*::* ** **:*:.:* ", "identical_positions": 195, "similar_positions": 196, "identity": "25.39%" }, { "cls_id": "homologset.agr.MGI:1888897", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P24470-1", "uniprot_id": "CP2CN_RAT", "id": "P24470-1", "name": "Cytochrome P450 2C23", "aln": "-------------MELLGFTTLALVVSVTCLSLLSVWTKLR--TRGRLPPGPTPLPIIGNLLQLNLKDIPAS-----LSKLAKEYG-PVYTLYFGTSPTVVLHGYDVVKEALLQQGDEFLGRGPLPIIEDTHKGYGLIFSNGERWKVMRRFSLMTLRNFGMGKR----------SLEERVQEEARCLVEELQKTKAQPFDPTFILACAPCNVICSILFNDRFQYN-DKTFLNLMDLLNKNFQQVNSVWCQMYNLWPTIIKYLPG--KHIEFAKRIDDVKNFILEKVKEHQKSLDPAN----------------------PRDYIDCFLSKIEEEKD----NLKSEFH--------------------LENLAVCGSNLFTAGTETTSTTLRFGLLLLMKYPEVQAKVHEELDRVIGRHQP---PSMKDKMKLPYTDAVLHEIQRYITLLPSSLPHAVVQDTKFRDYVIPKGTTVLPMLSSVMLDQKEFANPEKFDPGHFLDKNGCFKKTDYFVPFSLGKRACVGESLARMELFLFFTTLLQKFSLKTLVEPKDLDIKPITTGIINLPPPYKLCLVPR----------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "E9Q5K4-1", "uniprot_id": "CP2CN_MOUSE", "id": "E9Q5K4-1", "name": "Cytochrome P450 2C44", "aln": "-------------MELLGLPTLALLVLVMSLSLLSVWTKMR--TGGRLPPGPTPLPIIGNILQLDLKDIPAS-----LSKLAKEYG-PVYTLYFGSWPTVVLHGYDVVKEALLNQGDEFLGRGPLPIIEDSQKGHGIVFSEGERWKLLRRFSLMTLKNFGMGKR----------SLEERVQEEARCLVEELHKTEAQPFDPTFILACAPCNVICSILFNERFPYN-DKTFLNLMDLLNKNFYQLNSIWIQMYNLWPTIMKYIPG--KHREFSKRLGGVKNFILEKVKEHQESLDPAN----------------------PRDYIDCFLSKIEEEKH----NLKSDFN--------------------LENLAICGSNLFTAGTETTSTTLRFGLLLLVKHPEVQAKVHEELDRVIGRHQP---PSMKDKMKLPYTDAVLHEIQRYITLLPSSLPHAVVQDTKFRHYVIPKGTAVFPFLSSILLDQKEFPNPEKFDPGHFLDKNGCFKKTDYFVPFSLGKRSCVGEGLARMELFLFFTTILQKFSLKALVEPKDLDIKPVTTGLFNLPPPYKLRLVPR----------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9VW43-1", "uniprot_id": "CP305_DROME", "id": "Q9VW43-1", "name": "Probable cytochrome P450 305a1", "aln": "-----------------MSALIFLCAILIGFVIYSLISSAR--RPKNFPPGPRFVPWLGNTLQFRKEASAVGGQHILFERWAKDFRSDLVGLKLGREYVVVALGHEMVKEVQLQEVFEGRPDNFFLRLRTMGTRKGITCTDGQLWYEHRHFAMKQMRNVGYGRS----------QMEHHIELEAEELLGQLERTEEQPIEPVTWLAQSVLNVLWCLIAGKRIARQEDGTLRRLLDLMNR-RSKLFDICGGLLAQFPWLRHVAPDRTGYNLIQQLNTELYGFFMDTIEEHRRQLAKDP----------------------SPAESDLIYAYLQEMKDRSAGGESSTFN--------------------ETQLVMTILDFFIAGSQTTSNTINLALMVLAMRPDVQEKLFSQVTASVAAASTDAFPHLSRREAFDYMDAFIMEVQRFFHITPITGPRRALWATKLGGYDIPKNATILISLRSVHLDKEHWKDPLEFRPERFIDSAGKCFKDEYFMPFGMGRRRCLGDALARACIFSFLVRIVQHFSVVLPAG--ESPSMVLLPGITLTPKPYKVQFVKRT---------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VWR5-1", "uniprot_id": "CP306_DROME", "id": "Q9VWR5-1", "name": "Cytochrome P450 306a1", "aln": "MSADIVDIGHTGWMPSVQSLSILLVPGALVLVILYLCERQCNDLMGAPPPGPWGLPFLGYLPFLDARAPHKS-----LQKLAKRYG-GIFELKMGRVPTVVLSDAALVRDFFRRDVMTG--RAPLYLTHGIMGGFGIICAQEDIWRHARRETIDWLKALGMTRRPGELRARLERRIARGVDECVRLFDTEAKKSCASEVNPLPALHHSLGNIINDLVFGITYKRD-DPDWLYLQRLQEEGVKLIG--VSGVVNFLPWLRHLPANVRNIRFLLEGKAKTHAIYDRIVEACGQRLKEKQKVFKELQEQKRLQRQLEKEQLRQSKEADPSQEQSEADEDDEESDEEDTYEPECILEHFLAVRDTDSQLYCDDQLRHLLADLFGAGVDTSLATLRWFLLYLAREQRCQRRLHELLLPLGP------SPTLEELEPLAYLRACISETMRIRSVVPLGIPHGCKENFVVGDYFIKGGSMIVCSEWAIHMDPVAFPEPEEFRPERFLTADGAYQAPPQFIPFSSGYRMCPGEEMARMILTLFTGRILRRFHLELPSG--TEVDMAGESGITLTPTPHMLRFTKLPAVEMRHAPDGAVVQD", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : * : : : **** :* :* : . . :.: ** : : * :* .** . :*:: .: : . *: :: : * *: :: :: .* : : . :: .. : : .:: . .:* * : *:: :: . : * * * :. : : * : : .. : : : :: . * * : :. . .. :. :* ::* ** :*: *:. *: * * ::.. : * :. : * * : * * : * *: . * * .: :. :: :* : :* :* * :*: * *:**. * * * *: :** : * ::::* : .*: * *: : :. ", "identical_positions": 65, "similar_positions": 126, "identity": "10.96%" }, { "cls_id": "homologset.agr.MGI:1888902", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A0G2JV35-1", "uniprot_id": "A0A0G2JV35_RAT", "id": "A0A0G2JV35-1", "name": "N-alpha-acetyltransferase 80", "aln": "MELILSTSPAKLTLDPACQPELTLRFNLTKLTLDPARQSELSLSPRLAELTLDSTCHPEMSLSPGPAELTGDPQHQAKESLVPKLAELTLEPVHCRPELMSACADLINDQWPRSRASRLHSLGQSSDAFPLCLMLLSPQPTPGAAPIVVGHARLSRVLDHPHSLLVETVVVARALRGRGFGRRLMEGLEAFARARG-FQRLHLTTHDQLYFYAHLGYQLGEPVQGLAFTNRRLPTNVLRAFSKPPCPQPPCKAPVLAAQAIPRSSKGPPLPPPPPLP--LTTSPPPSPEPLPQSPLETRYRDLKGCPIFWMEKDI", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9R123-1", "uniprot_id": "NAA80_MOUSE", "id": "Q9R123-1", "name": "N-alpha-acetyltransferase 80", "aln": "MELILSTSPAKLTLDPARQPELTLRFNLSKLTLDPARQPELSLSPRLAELTLDPTCHPEMSLSPGPAELTLDPQHQAKELPVPKLPELILEPVHCRPELMSACADLINDQWPRSRASRLHSLGQSSDAFPLCLMLLSPQPTPGAAPVVVGHARLSRVLDQPHSLLVETVVVARPLRGRGFGRRLMEGLEAFARARG-FRRLHLTTHDQLYFYAHLGYQLGEPVQGLAFTNRRLSTTVLRAFSKPPCPQPPCKEPILAAQAVPRSSKGPPLPPPPPLPQSLTASPPPSPEPLPQSPLETCYRDLKGCPIFWMEKDI", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q93015-1", "uniprot_id": "NAA80_HUMAN", "id": "Q93015-1", "name": "N-alpha-acetyltransferase 80", "aln": "MELILSTSPAELTLDPACQP----------------------------KLPLDSTCQPEMTFNPGPTELTLDPEHQPEETPAPSLAELTLEPVHRRPELLDACADLINDQWPRSRTSRLHSLGQSSDAFPLCLMLLSPHPTLEAAPVVVGHARLSRVLNQPQSLLVETVVVARALRGRGFGRRLMEGLEVFARARG-FRKLHLTTHDQVHFYTHLGYQLGEPVQGLVFTSRRLPATLLNAFPTAPSPRPPRKAPNLTAQAAPRGPKGPPLPPPPPLPECLTISPPVPSGPPSKSLLETQYQNVRGRPIFWMEKDI", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q59DX8-1", "uniprot_id": "NAA80_DROME", "id": "Q59DX8-1", "name": "N-alpha-acetyltransferase 80", "aln": "-----------------------------------------------------------------MRYIKSEPYYEGLPPFNVSGSPFNVVPIHNYPELMKDTCALINAEWPRSETARMRSLEASCDSLPCSLVLTT-----EGMCRVIAHLKLSPINSKKKACFVESVVVDKRHRGQGFGKLIMKFAEDYCRVVLDLKTIYLSTIDQDGFYERIGYEYCAPITMYGPRHCELPS-------------------------------------------------------------------LQNAKKKYMKKVL", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :. :* :: . . : : *:* ***:. . *** :****.::*::** *.*::* .*:* : . *:.* :** : .: :: :**:*** : **:***: :*: * :.*. :: ::*:* ** ** ::**: *: .*.: ::. :*:* :", "identical_positions": 50, "similar_positions": 62, "identity": "15.87%" }, { "cls_id": "homologset.agr.MGI:1888908", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I6AAN3-1", "uniprot_id": "A0A8I6AAN3_RAT", "id": "A0A8I6AAN3-1", "name": "Delta-1-pyrroline-5-carboxylate synthase", "aln": "-MLRHVQRSGLQPFSQRLLPWVQSIALPRSHRVQPSAIRHVRSWSNIPFITVPLSRAHGKPFAHRSELKHAKRIVVKLGSAVVTRGDECGLALGRLASIVEQVSVLQNQGREMMLVTSGAVAFGKQRLRHEILLSQSVRQALHSGQNHLKEMAIPVLEARACAAAGQSGLMALYEAMFTQYSICAAQILVTNLDFHDEQKRRNLNGTLHELLRMNIVPIVNTNDAVVPPAEPNSDLQGV---NVISVKDNDSLAARLAVEMKTDLLIVLSDVEGLFDSPPGSDDAKLIDIFYPGDQQSVTFGTKSRVGLGGMEAKVKAALWALQGGTSVVIANGTHPKVSGHVITDIVEGKKVGTFFSEVKPAG--PTVEQQGEMARSGGRMLATLEPEQRAEIINHLADLLTDQREEILLANKKDLEEAE--GRLAGPLLKRLSLSTS-KLNSLAIGLRQIAASSQESVGRVLRRTRIAKNLELEQVTVPIGVLLVIFESRPDCLPQVAALAIASGNGLLLKGGKEAMHSNRILHLLTQEALSIHGVKE-----AIQLVNTREEVEDLCRLDKIIDLIIPRGSSQLVRDIQKAAKGIPVMGHSEGICHMYVDSEASVDKVTRLVRDSKCEYPAACNALETLLIHR------DLLRTPLFDQIIDMLRVEQVKIHAGPKFASY---------LTFSPSEVKSLRTEYGDLEVCIEVVDSVQEAIDHIHKYGSSHTDVIVTENEKTAEFFLQHVDSACVFWNASTRFSDGYRFGLGAEVGISTSRIHARGPVGLEGLLTTKWLLRGQDHVVSDFS-EHGRLKYLHENLPVPQ-----RHFS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9Z110-1", "uniprot_id": "P5CS_MOUSE", "id": "Q9Z110-1", "name": "Delta-1-pyrroline-5-carboxylate synthase", "aln": "-MLRHMHRSGVQPFRQRLLPWVQSIAVPRSNRVQPSAIRHVRSWSNIPFITVPLSRAHGKPFAHRSELKHAKRIVVKLGSAVVTRGDECGLALGRLASIVEQVSVLQNQGREMMLVTSGAVAFGKQRLRHEILLSQSVRQALHSGQNHLKEMAIPVLEARACAAAGQSGLMALYEAMFTQYSICAAQILVTNLDFHDEQKRRNLNGTLHELLRMNIVPIVNTNDAVVPPAEPNSDLQGV---NVISVKDNDSLAARLAVEMKTDLLIVLSDVEGLFDSPPGSDDAKLIDIFYPGDQQSVTFGTKSRVGLGGMEAKVKAALWALQGGTSVVIANGTHPKVSGHVITDIVEGKKVGTFFSEVKPAG--PTVEQQGEMARSGGRMLATLEPEQRAEIINHLADLLTDQREEILLANKKDLEEAE--GRLASPLLKRLSLSTS-KLNSLAIGLRQIAASSQESVGRVLRRTRIAKNLELEQVTVPIGVLLVIFESRPDCLPQVAALAIASGNGLLLKGGKEAAHSNRILHLLTQEALSIHGVKE-----AIQLVNTREEVEDLCRLDKIIDLIIPRGSSQLVRDIQKAAKGIPVMGHSEGICHMYVDSEASVDKVTRLVRDSKCEYPAACNALETLLIHR------DLLRTPLFDQIIDMLRVEQVKIHAGPKFASY---------LTFSPSEVKSLRTEYGDLEVCIEVVDSVQEAIDHIHKYGSSHTDVIVTENEKTAEFFLQHVDSACVFWNASTRFSDGYRFGLGAEVGISTSRIHARGPVGLEGLLTTKWLLRGQDHVVSDFS-EHGSLKYLHENLPVPQ-----RNFS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P54886-1", "uniprot_id": "P5CS_HUMAN", "id": "P54886-1", "name": "Delta-1-pyrroline-5-carboxylate synthase", "aln": "-MLSQVYRCGFQPFNQHLLPWVKCTTVFRSHCIQPSVIRHVRSWSNIPFITVPLSRTHGKSFAHRSELKHAKRIVVKLGSAVVTRGDECGLALGRLASIVEQVSVLQNQGREMMLVTSGAVAFGKQRLRHEILLSQSVRQALHSGQNQLKEMAIPVLEARACAAAGQSGLMALYEAMFTQYSICAAQILVTNLDFHDEQKRRNLNGTLHELLRMNIVPIVNTNDAVVPPAEPNSDLQGV---NVISVKDNDSLAARLAVEMKTDLLIVLSDVEGLFDSPPGSDDAKLIDIFYPGDQQSVTFGTKSRVGMGGMEAKVKAALWALQGGTSVVIANGTHPKVSGHVITDIVEGKKVGTFFSEVKPAG--PTVEQQGEMARSGGRMLATLEPEQRAEIIHHLADLLTDQRDEILLANKKDLEEAE--GRLAAPLLKRLSLSTS-KLNSLAIGLRQIAASSQDSVGRVLRRTRIAKNLELEQVTVPIGVLLVIFESRPDCLPQVAALAIASGNGLLLKGGKEAAHSNRILHLLTQEALSIHGVKE-----AVQLVNTREEVEDLCRLDKMIDLIIPRGSSQLVRDIQKAAKGIPVMGHSEGICHMYVDSEASVDKVTRLVRDSKCEYPAACNALETLLIHR------DLLRTPLFDQIIDMLRVEQVKIHAGPKFASY---------LTFSPSEVKSLRTEYGDLELCIEVVDNVQDAIDHIHKYGSSHTDVIVTEDENTAEFFLQHVDSACVFWNASTRFSDGYRFGLGAEVGISTSRIHARGPVGLEGLLTTKWLLRGKDHVVSDFS-EHGSLKYLHENLPIPQ-----RNTN", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AB32U570-1", "uniprot_id": "A0AB32U570_DANRE", "id": "A0AB32U570-1", "name": "Delta-1-pyrroline-5-carboxylate synthase", "aln": "MSLQRMFSC------SRLLARPNALQTFRRAASQG---------------KMPLARAHGKSFAHRSELRQAKRIVVKLGSAVVTRGDECGLALGRLASIVEQVAMLQNQGREMMIVTSGAVAFGKQRLRHEILLSQSVRQALHSGQNQLKDMSLPVLEARACAAAGQSGLMALYEAMFTQYSTCTAQILVTNLDFHDEQKRRNLNSTLYELLRMNIVPIINTNDAVVPPPEPNSDLQG-----VISIKDNDSLAARLAVEMRADLLIALSDVEGLYDSPPGSDDAKLLDTFYPGDQQSITYGTKSRVGIGGMEAKVKAALWALQGGTSVVIANGTHPKVTGHVITDIVEGKKVGTFFSEVKPAG--PTVEQQTEMARSAGRTLASLEPEQRSDIICALADLLTERKEEILSANKKDMENAVNTGRLSPAMLKRLSLSSS-KLNSLSIGLRQIAVSSQDSVGRVLRRTRVANNLELEQITVPIGVLLVIFESRPDCLPQVSALAIASGNALLLKGGKEAANTNRILHELAQEALSIHGVKD-----AIQLVSTREEVEDLCRLEKMIDLIIPRGSSQLVRDIQRAAKGIPVLGHSEGICHVYVDHEASIDKAIKIIRDSKCDYPAACNAMETLLVHR------DLLRTPVFDQIIDMLRTEQVKIHAGPKFASY---------LTFSPSEVKSLRTEYGDLECCIEVVDSMQEAIDHIHKYGSSHTDVIVTENENTAEQFLQQLDSACVFWNASSRFADGYRFGLGAEVGISTARIHARGPVGLEGLLTTKWVLRGEGHTVADFS-EHGSMTYLHENLPVAQLLPGYRTTS", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VNW6-1", "uniprot_id": "Q9VNW6_DROME", "id": "Q9VNW6-1", "name": "Delta-1-pyrroline-5-carboxylate synthase", "aln": "-MLQNSFKLAQS---LRNGFYRNAWRAFSSHGPRQPLVSP----------ERRLEKAH-PTFTERSQLKYARRLVVKLGSAVITREDNHGLALGRLASIVEQVAECHLEGREVMMVTSGAVAFGKQKLAQELLMSLSMRETLNPKDS--KEFDGATLEPRAAAAVGQSGLMSLYDAMFAQYGVKIAQVLVTKPDFYNEETRNNLFCTLSELISLNIVPIINTNDAVSPPMFIRDDEPAGGARRGIPIKDNDSLSAMLAAEVQADLLILMSDVDGIYNKPPWEDGAKLMHTYTSDDSNSIEFGKKSKVGTGGMDSKVKAATWALDRGVSVVICNGMQEKA----IKTIIGGRKVGTFFTEATESANAVPVEVMAENARTGSRQMQALTPAQRASAVNTLADLLVSREKFILDANAKDLAEAQK-SGLAKPLLSRLSLNPA-KLKNLSVGLKQIAEDSHKNVGRVLRRTRLADQLELKQVTVPIGVLLVIFESRPDSLPQVAALAMASANGLLLKGGKEAAHSNKALMELVKEALATVGAEH-----AVSLVSTREEISDLLSMENHIDLIIPRGSSDLVRSIQQQSLHIPVLGHAEGVCHVYIDRDADLEKALRIARDAKCDYPAACNAMETLLIHE------DLMSGAIFGDVCNMLKREGVKIYAGPRLNQQ---------LTFGPPAAKSLKHEYGALECCIEVVPSLDEAINHIHTYGSSHTDVIVTENDAAARQFLGSVDSACVFHNASSRFADGFRFGLGAEVGISTARIHARGPVGVEGLLTTKWILEGQDHAAADFA-EGGGRTWLHETLPLD----------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P54885-1", "uniprot_id": "PROA_YEAST", "id": "P54885-1", "name": "Gamma-glutamyl phosphate reductase", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSSS---------QQIAKNARKAGNILKTISNEGRSDILYKIHDALKANAHAIEEANKIDLAVAK-ETGLADSLLKRLDLFKGDKFEVMLQGIKDVAELEDP-VGKVKMARELDDGLTLYQVTAPVGVLLVIFESRPEVIANITALSIKSGNAAILKGGKESVNTFREMAKIVNDTIAQFQSETGVPVGSVQLIETRQDVSDLLDQDEYIDLVVPRGSNALVRKIKDTTK-IPVLGHADGICSIYLDEDADLIKAKRISLDAKTNYPAGCNAMETLLINPKFSKWWEVLENLTLEGGVTIHATKDLKTAYFDKLNELGKLTEAIQCKTVDADEEQDFDKEFLSLDLAAKFVTSTESAIQHINTHSSRHTDAIVTENKANAEKFMKGVDSSGVYWNASTRFADGFRYGFGAEVGISTSKIHARGPVGLDGLVSYQYQIRGDGQVASDYLGAGGNKAFVHKDLDIKTVTL------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ::. : : **.... : :: *:. : : * * . . * ** *: * *: .:*.**.* . *:: : *::::* .. **:* .: . * * *:*.*:***********: :.:::**:: *.*. :******: :: : : :.::::: : ::.*:.**:::.** :: ***::****. ***.*: : ***:**::*:* :*:* :*.: *. :: *:* :***.***:****:: ::: : : : :* :: . *... :.: *: *: . :.* . :.**:**:.:.* ***.****:. *. *: :**: *: ***:**:**:*:*:********::********::**:: :: :.*..:..:*: * ::*: * : ", "identical_positions": 140, "similar_positions": 163, "identity": "16.87%" }, { "cls_id": "homologset.agr.MGI:1888921", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9R1J8-1", "uniprot_id": "P3H1_RAT", "id": "Q9R1J8-1", "name": "Prolyl 3-hydroxylase 1", "aln": "-----------MVAVAAAAASRATAESEPEWNVAAPDLLYAEGTAAYARGDWPGVVLNMERALRSRAALRALRLRCRTRCATELPWAPDLDLGPASSLNHDPGAAALHDLRFFGALLRRAACLRRC----LGPPSAHLLSEELDLEFNKRSPYNYLQVAYFKINKLEKAVAAAHTFFVGNPEHMEMRQNLDYYQTMSGVKEEDFKDLEAKPHMHEFRLGVRLYSEEKPLEAVPHLEAALQEYFVADEECRALCEGPYDYDGYNYLDYSADLFQAITDHYVQVLSCKQNCVTELASHPSREKPFEDFLPSHYNYLQFAYYNIGNYTQAIECAKTYLLFFPNDEVMSQNLAYYTAVLGEEEASSISPRENAQEYRHRSLLEKELLFFAYDIFGIPFVDPDSWTPEEVIPKRLQEKQKSERETAVRISQEIGNLMKEIETLVEEKTKESLDVSRLTR----------EGGPLLYEGINLTMNSKVLNGSQRVVMDGVISDDECQELQRLTNAAATSGDGYRGQTSPHTPNEKFYGVTVLKALKLGQEGKVPLQSAHMYYNVTEKVRRVMESYFRLDTPLYFSYSHLVCRTAIEESQAERKDSSHPVHVDNCILNAESLVCIKEPPAYTFRDYSAILYLNGDFDGGNFYFTELDAKTVTAEVQPQCGRAVGFSSGTENPHGVKAVTRGQRCAIALWFTLDPRHSERDRVQADDLVKMLFSPEEVDLPQ--------------------------------------------------------------------------------------EQPLPDQQGSPKPGE--------------ESLSDRESQPKDEL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q3V1T4-1", "uniprot_id": "P3H1_MOUSE", "id": "Q3V1T4-1", "name": "Prolyl 3-hydroxylase 1", "aln": "MAVSERRLLAAMLAVAAAAALRVAAESEPGWDVAAPDLLYAEGTAAYSRGDWPGVVLNMERALRSRAALRALRLRCRTRCATELPWAPDLDLGPDPSLSQDPGAAALHDLRFFGAVLRRAACLRRC----LGPPSAHLLSEELDLEFNKRSPYNYLQVAYFKINKLEKAVAAAHTFFVGNPEHMEMRQNLDYYQTMSGVKEADFRDLEAKPHMHEFRLGVRLYSEEKPQEAVPHLEAALQEYFVADEECRALCEGPYDYDGYNYLDYSADLFQAITDHYVQVLNCKQNCVTELASHPSREKPFEDFLPSHYNYLQFAYYNIGNYTQAIECAKTYLLFFPNDEVMHQNLAYYTAMLGEEEASSISPRENAEEYRRRSLLEKELLFFAYDIFGIPFVDPDSWTPEEVIPKRLQEKQKSERETAVRISQEIGNLMKEIETLVEEKTKESLDVSRLTR----------EGGPLLYEGISLTMNSKVLNGSQRVVMDGVISDDECQELQRLTNAAATSGDGYRGQTSPHTPNEKFYGVTVLKALKLGQEGKVPLQSARMYYNVTEKVRRVMESYFRLDTPLYFSYSHLVCRTAIEESQAERKDSSHPVHVDNCILNAEALMCIKEPPAYTFRDYSAILYLNGDFDGGNFYFTELDAKTVTAEVQPQCGRAVGFSSGTENPHGVKAVTRGQRCAIALWFTLDPRHSERDRVQADDLVKMLFSPEEVDLPQ--------------------------------------------------------------------------------------EQPLPDQQGSPEPGE--------------ESLSDRGSLHKDEL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q32P28-1", "uniprot_id": "P3H1_HUMAN", "id": "Q32P28-1", "name": "Prolyl 3-hydroxylase 1", "aln": "MAVRALKLLTTLLAVVAAAS-QAEVESEAGWGMVTPDLLFAEGTAAYARGDWPGVVLSMERALRSRAALRALRLRCRTQCAADFPWELDPDWSPSP--AQASGAAALRDLSFFGGLLRRAACLRRC----LGPPAAHSLSEEMELEFRKRSPYNYLQVAYFKINKLEKAVAAAHTFFVGNPEHMEMQQNLDYYQTMSGVKEADFKDLETQPHMQEFRLGVRLYSEEQPQEAVPHLEAALQEYFVAYEECRALCEGPYDYDGYNYLEYNADLFQAITDHYIQVLNCKQNCVTELASHPSREKPFEDFLPSHYNYLQFAYYNIGNYTQAVECAKTYLLFFPNDEVMNQNLAYYAAMLGEEHTRSIGPRESAKEYRQRSLLEKELLFFAYDVFGIPFVDPDSWTPEEVIPKRLQEKQKSERETAVRISQEIGNLMKEIETLVEEKTKESLDVSRLTR----------EGGPLLYEGISLTMNSKLLNGSQRVVMDGVISDHECQELQRLTNVAATSGDGYRGQTSPHTPNEKFYGVTVFKALKLGQEGKVPLQSAHLYYNVTEKVRRIMESYFRLDTPLYFSYSHLVCRTAIEEVQAERKDDSHPVHVDNCILNAETLVCVKEPPAYTFRDYSAILYLNGDFDGGNFYFTELDAKTVTAEVQPQCGRAVGFSSGTENPHGVKAVTRGQRCAIALWFTLDPRHSERDRVQADDLVKMLFSPEEMDLSQ--------------------------------------------------------------------------------------EQPLDAQQGPPEPAQ--------------ESLSGSESKPKDEL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A0R4I9E8-1", "uniprot_id": "A0A0R4I9E8_DANRE", "id": "A0A0R4I9E8-1", "name": "procollagen-proline 3-dioxygenase", "aln": "------MWTSLCLISILSTVHFTRCDPQINAGFQPYDLLFDNAVEAYYKQDWLAVILNMEKALRNKGALRKIQTHCRLSCANNTAFGEPLPGLGIP----IPGSGSVEDLAFFQRILQRADCVNACESEKLGPATLHKVSENVELEFKKRTPYNYLQVAYFKINKLDKAVAAANTFFMANPEHVEMKQNLDYYRMMAGVQETDFKDLEEKPHMAEFLQGKIHYSTEDFVPAVEHFEAAVEEYFGAYEECRVLCEGAFDYDGYNYMEYNADLFQSMTDHYLHVLSCKQNCAVELASTAGRETPFEDFLPSHFNYLQFSYYNMEKFEQAIECAKTYLLFHPEDAVMAQNIAYYSAVLGDEKAVNITEREVVKQHIKRSLLEKELLYYGYEMFGKAFVDPDTWTPEEVMPKKLRDKQKVDKETAARITEEIGNLMKEIETLVEEKSKESSDIVKVVKDEIKPAAAPDTASKLPSDDITITMTSEVLSGSHRVVLDGVTTSDECQELHQITTTAALQ-DAFKAVPSPHSASEMFQDVPVLKAL---QEGLIPTKSAHLLSNLGEKVRKVLESYFALESTLYFSSSNLVCRSATEKQEAS----------ADCLLISELNECIKVLSTNTNQGYSAILYLNDDFEGGDFIFTESDGKAVSAAVKPQCGRVVGFRAGQENLHGVSAVTKGQRCAVVLHFTLDPQHSQEERSQTEELLKKLSSPVKVDIQKTATDSQEYPSKPEGTIPAETTEKDKSKATDDNTAETKTDNKASKKSEKPKAKTTKKTSKAETQTKAKADKTKTTTAEKKKTKPASKTKPVTTDKKEKPPGKKTAANDKKTKPKATEAKDSKAEKHNDEL", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : :: . :.: .. . ***: :.. ** : ** .*:*.**:***.:.*** :: :** ** : .: . .*:.::.** ** :*:** *:. * ***.: * :**:::***.**:***************:******:***:.****:**:******: *:**:* **:*** :*** ** * ** *. ** *:***::*** * ****.****.:*******::*.*****::****::**.*****..**** ..**.*********:*****:***: :: **:*********.*:* ** **:***:*:**:*.: .* ** .::: :*********::.*::** .*****:******:**:*::*** ::***.**::****************:*** *: ::.: .. * :.*.:**.*::*.**:***:*** :..*****:::*..** . *.::. .***:..* * .*.*:*** *** :* :**:: *: ****:::**** *::.**** *:****:* *: :*. :*:* :* *:* .: * :.********.**:**:* *** *.*:*:* *:*****.*** :* ** ***.***:*****:.* *****:**:.:* *:::*:* * ** ::*: : :*: :: *.: *: .. . :***", "identical_positions": 374, "similar_positions": 212, "identity": "43.85%" }, { "cls_id": "homologset.agr.MGI:1888939", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9R1T4-1", "uniprot_id": "SEPT6_MOUSE", "id": "Q9R1T4-1", "name": "Septin-6", "aln": "-----MAAADIARQVGEDCRTVPLAGHVGFDSLPDQLVNKS--------------------VSQGFCFNILCVGETGLGKSTLMDTLFNTKFE--------GEPATHTQPGVQLQSNTYDLQ-ESNVGLKLTIVSTVGFGDQINKEDSYKPIVEFIDAQFEAYLQEELKIRRVLHSYHDSRIHVCLYFIAPTGHSLKSLDLVTMKKLDSKVNIIPVIAKSDAISKSELAKFKIKITSELVSNGVQIYQFPTDDE----SVSEINGTMNAHLPFAVVGSTEEVKIGNKMMR--ARQYPWGTVQVENEAHCDFVKLREMLIRVNMEDLREQTHARHYELYRRCKLEEMGFKDTDPDSKPFSLQ----------------ETYEAKRNEFLGELQKKEEEMRQMFVQRVKEKEAELKEAEKELHEKFDRLKKLHQE-------------------------EKKKLEDKKKCLDEEMNAFKQRKAAAELLQSQGSQAGGSQTLKRDKEKKNNPWLCIE-------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8I6AA08-1", "uniprot_id": "A0A8I6AA08_RAT", "id": "A0A8I6AA08-1", "name": "Septin", "aln": "-----MAAADIARQVGEDCRTVPLAGHVGFDSLPDQLVNKS--------------------VSQGFCFNILCVGETGLGKSTLMDTLFNTKFE--------GEPTTHTQPGVQLRSSTYDLQ-ESNVGLKLTIVSTVGFGDQINKEDSYKPIVEFIDAQFEAYLQEELKIRRVLHSYHDSRIHACLYFIAPTGHSLKSLDLVTMKKLDSKVNIIPIIAKSDAISKSELAKFKIKITSELVSNGVQIYQFPTDDE----SVAEINGTMNAHLPFAVVGSTEEVKIGNKMMR--ARQYPWGTVQVENEAHCDFVKLREMLIRINMEDLREQTHARHYELYRRCKLEEMGFKDTDPDSKPFSLQ----------------ETYEAKRNEFLGELQKKEEEMRQMFVQRVKEKEAELKEAEKELHEKFDRLKKLHQE-------------------------EKKKLEDKKKCLDEEMNAFKQRKAAAELLQSQGSQAGGSQTLKRDKEKKNWQRSGFDAYWPADRGKYRVTM-----------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q14141-1", "uniprot_id": "SEPT6_HUMAN", "id": "Q14141-1", "name": "Septin-6", "aln": "-----MAATDIARQVGEGCRTVPLAGHVGFDSLPDQLVNKS--------------------VSQGFCFNILCVGETGLGKSTLMDTLFNTKFE--------GEPATHTQPGVQLQSNTYDLQ-ESNVRLKLTIVSTVGFGDQINKEDSYKPIVEFIDAQFEAYLQEELKIRRVLHTYHDSRIHVCLYFIAPTGHSLKSLDLVTMKKLDSKVNIIPIIAKADAISKSELTKFKIKITSELVSNGVQIYQFPTDDE----SVAEINGTMNAHLPFAVIGSTEELKIGNKMMR--ARQYPWGTVQVENEAHCDFVKLREMLIRVNMEDLREQTHTRHYELYRRCKLEEMGFKDTDPDSKPFSLQ----------------ETYEAKRNEFLGELQKKEEEMRQMFVQRVKEKEAELKEAEKELHEKFDRLKKLHQD-------------------------EKKKLEDKKKSLDDEVNAFKQRKTAAELLQSQGSQAGGSQTLKRDKEKKNNPWLCTE-------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M2BKJ6-1", "uniprot_id": "A0A8M2BKJ6_DANRE", "id": "A0A8M2BKJ6-1", "name": "Septin", "aln": "MQERTMAATEIARQAGEGARAVPLSGHVGFDSMPDQLVNKS--------------------VNHGFCFNILCVGETGLGKSTLMDTLFNTKFE--------GEPTQHNQPGVQLKSNTYELQ-ESNVRLKLTVVNTVGFGDQINKEDSYKSIVEFIDAQFEAYLQEELKIKRTLHSYHDTRIHACLYFIAPTGHSLKSLDLVTMKKLDSKVNIIPIIAKSDAISKSELAKFKIKITSELVSNGVQIYQFPTDDE----TVAEINSTMNGHLPFAVVGSTEEVKIGNKMVR--ARQYPWGTVQVENENHCDFVKLREMLIRVNMEDLREQTHTRHYELYRRCKLEEMGFKDTDPDSKPFSLQ----------------ETYEAKRNEFMGELQKKEEEMRQMFVQRVKEKEAELKEAEKELHEKFDRLKKLHQD-------------------------EKKKLEDKKKSLDDELNGFKQKKTAAELLQSQNQQPGGSATLKKDKERKNSGFL----------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P54359-1", "uniprot_id": "SEPT2_DROME", "id": "P54359-1", "name": "Septin-2", "aln": "----MSVEVDFVDKKEVHLRTLKQSGHVGFDSLPDQLVNKS--------------------VQNGFVFNVMCIGETGLGKSTLMDTLFNTSFE--------STPSPHTLPSVKLKAHTYELQ-ESNVRLKLTICDTVGYGDQINKDDSFKAVVDYIDAQFENYLQEELKIKRSLVTCHDSRIHICLYFICPTGHGLKSLDLVCMKKLDSKVNIIPVIAKADTISKVELQRFKAKIIQELNANGVHIYQFPTDDE----TVAETNTSMNSHIPFAVVGSTEFIKVGNKLIR--ARQYPWGTVQVENETHCDFVKLREMLIRTNMEDMREKTHTRHYELYRQKRLEQMGFSDVDSDNKPISFQ----------------QTFEAKRSNHLAELQSKEEEVRQMFVQRVKEKEAELKESEKDLHAKFEKLKRDHAE-------------------------EKRKLEESRKALEEDYLDFQRRK-------QQLATAHHTLTLGKSKKK----------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P32458-1", "uniprot_id": "CDC11_YEAST", "id": "P32458-1", "name": "Cell division control protein 11", "aln": "-MSGIIDASSALRKRKHLKRGITFTVMIVGQSGSGRSTFIN----------------------------TLCGQQVVDTSTTILLP-----------------TDTSTEIDLQLREETVELEDDEGVKIQLNIIDTPGFGDSLDNSPSFEIISDYIRHQYDEILLEESRVRRNPR-FKDGRVHCCLYLINPTGHGLKEIDVEFIRQLGSLVNIIPVISKSDSLTRDELKLNKKLIMEDIDRWNLPIYNFPFDEDEISDEDYETNMYLRTLLPFAIIGSNEVYEMGGDVGTIRGRKYPWGILDVEDSSISDFVILRNALLISHLHDLKNYTHEILYERYRTEALSGESVAAESIRPNLTKLN---------------GSSSSSTTTRRNTNPFKQSNNINNDVLNPASDMHGQSTGENNETYMTREEQIRLEE--------------------------ERLKAFEERVQQELLLKRQELLQREKELREIEARLEKEAKIKQEE-------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "Q07657-1", "uniprot_id": "SHS1_YEAST", "id": "Q07657-1", "name": "Seventh homolog of septin 1", "aln": "MSTASTPPINLFRRKKEHKRGITYTMLLCGPAGTGKTAFANNLLETKIFPHKYQYGKSNASISSNPEVKVIAPTKVVSFNSKNGIPSYVSEFDPMRANLEPGITITSTSLELGGNKDQGKPEMNEDDTVFFNLIMTHGIGENLDDSLCSEEVMSYLEQQFDIVLAEETRIKRNPR-FEDTRVHVALYFIEPTGHGLREVDVELMKSISKYTNVLPIITRADSFTKEELTQFRKNIMFDVERYNVPIYKFEVDPEDDDLESMEENQALASLQPFAIITSDTRDSEGRYV-----REYPWGIISIDDDKISDLKVLKNVLFGSHLQEFKDTTQNLLYENYRSEKLSS-VANAEEIGPNSTKRQSNAPSLSNFASLISTGQFNSSQTLANNLRADTPRNQVSGNFKENEYEDNGEHDSAENEQEMSPVRQLGREIKQENENLIRSIKTESSPKFLNSPDLPERTKLRNISETVPYVLRHERILARQQKLEELEAQSAKELQKRIQELERKAHELKLREKLINQNKLNGSSSSINSLQQSTRSQIKKNDTYTDLASIASGRD", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . : * : : : : ..: . . :. :. .:. . . . : . . : :.. : :.: * * *:.::.. . : : .:: *:: * ** :::* .* *:* .**:* ****.*:.:*: ::.:.. .*::*:*:::*:::: ** : * :: .: **:* * : * * : ***:: * . * : *:**** :.:::. .*: *:: *: ::.:::: *: ** ** *. . : . : . .: . . ::: . : : ..: ::: . . . *: * : . : .. ", "identical_positions": 55, "similar_positions": 138, "identity": "9.86%" }, { "cls_id": "homologset.agr.MGI:1888971", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P63047-1", "uniprot_id": "ST4A1_RAT", "id": "P63047-1", "name": "Sulfotransferase 4A1", "aln": "------------MAESEAETPGTPGEFESKYFEFHGVR-----LPPFCRGKMEDIADFPVRPSDVWIVTYPKSGTSLLQEVVYLVSQGAD--------------PDEIGLMNIDEQLPVLEYPQ----PGLDIIKELTSP-------------RLIKSHLPYRFLPSDLHNGDSKVIYMARNPKDLVVSYYQFHRSLRTMSYRGTFQEFCRRFMNDKLGYGSWFEHVQEFWEHRMDANVLFLKYEDMHRDLVTMVEQLARFLGVS--CDKAQLESLIEHC---HQLVDQCCNAEALP-------VGRGRVGLWKDIFTVSMNEKFDLVYKQKMGKCD--------LTFDFYL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P63046-1", "uniprot_id": "ST4A1_MOUSE", "id": "P63046-1", "name": "Sulfotransferase 4A1", "aln": "------------MAESEAETPGTPGEFESKYFEFHGVR-----LPPFCRGKMEDIADFPVRPSDVWIVTYPKSGTSLLQEVVYLVSQGAD--------------PDEIGLMNIDEQLPVLEYPQ----PGLDIIKELTSP-------------RLIKSHLPYRFLPSDLHNGDSKVIYMARNPKDLVVSYYQFHRSLRTMSYRGTFQEFCRRFMNDKLGYGSWFEHVQEFWEHRMDANVLFLKYEDMHRDLVTMVEQLARFLGVS--CDKAQLESLIEHC---HQLVDQCCNAEALP-------VGRGRVGLWKDIFTVSMNEKFDLVYKQKMGKCD--------LTFDFYL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9BR01-1", "uniprot_id": "ST4A1_HUMAN", "id": "Q9BR01-1", "name": "Sulfotransferase 4A1", "aln": "------------MAESEAETPSTPGEFESKYFEFHGVR-----LPPFCRGKMEEIANFPVRPSDVWIVTYPKSGTSLLQEVVYLVSQGAD--------------PDEIGLMNIDEQLPVLEYPQ----PGLDIIKELTSP-------------RLIKSHLPYRFLPSDLHNGDSKVIYMARNPKDLVVSYYQFHRSLRTMSYRGTFQEFCRRFMNDKLGYGSWFEHVQEFWEHRMDSNVLFLKYEDMHRDLVTMVEQLARFLGVS--CDKAQLEALTEHC---HQLVDQCCNAEALP-------VGRGRVGLWKDIFTVSMNEKFDLVYKQKMGKCD--------LTFDFYL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VHH0-1", "uniprot_id": "Q9VHH0_DROME", "id": "Q9VHH0-1", "name": "", "aln": "--------MQLIYRELEEDILRRTNAVFPVQNCFVEVLPDQFIIPRKYVELGESIRSLPVYQDDVWMVSYPRTGSTWAQEMVWLLGHQLDYVAAEQDLRLRSPLIELSALFSIDHHETVAQKFG----NTVDLVRNLPRP-------------RFARSHLPWPLLPEQFETVKPRIVYTARNPKDLCVSYYHYFKLLHGMN--GDFEQFVDLFLEGHTPMGSYWRHVLPFWKRSQDDNVLFIKYEDMVKDLPSVVRRCARFLGVQSLLDVSTLQKLCDHLTFDKMRANKAVNLEKLLPESSSKFIRNGKIGDWRNHMGNEMSERFDEWTERHMRGSG--------LNFDYV-", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "A1Z9J8-1", "uniprot_id": "A1Z9J8_DROME", "id": "A1Z9J8-1", "name": "", "aln": "MENTPLKFPHEIRDVEESTNAELLDHFHGERTGFVQVGSEGYFFPHKYKDEAERYYNFEARPDDVWIATVPRSGTTWTQELIWLVANGLDFEHAQERPLTERFPFFEFPLFVHPKIKEELQEENRDSAEALEFIEKIARPGYEALSEIPRSQRRFIKTHFPFSLMPPSVLEKKCKVIYVVRDPKDVAVSYYHLNRLFRTQGYVGDFERYWHYFQNGLNPWLPYYSHVKEAREHAHLSNVLFLRYEDMLADLPGAINSIASFLECP--PKPEDMDRLLDHLSIRSFRENKSVNMHEMASVG---VLNKGEAGFVRSGAKTAYQPQQEFVENPKLLKSANEWVEQNIKSFKTI-", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * . . * * :* * .: . .***:.: *::*:: **:::*:.: * *: . : ::::.::. * *: ::*:*: ::* .. . :::* .*:***: ****: : :: . * *:.: * :. .:: ** :: ****::**** ** :. * ** . :: * :* ::. * . : : .*. * :. . : : : :: . .*. ", "identical_positions": 53, "similar_positions": 89, "identity": "15.06%" }, { "cls_id": "homologset.agr.MGI:1888978", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "F1M4Q9-1", "uniprot_id": "F1M4Q9_RAT", "id": "F1M4Q9-1", "name": "Netrin-4", "aln": "MGSCARLLLLWGCSAVAAGFNGVSG--VNSRCEKACNPRMGNLALGRKLQADTTCGQNATELFCFYSENADLTCRQPKCDKCNGAHSHLAHPPSAMADSSFRFPRTWWQSAEDVHREKIQLDLEAEFYFTHLIMVFKSPRPAAMVLDRSQDFGKTWKPYKYFATNCSATFGLEDDVVKKGAICTSRYSNPFPCTGGEVIFRALSPPYDIENPYSAKVQEQLKITNLRVRLLKRQSCPCQRNDLNAKPHHFTHYAIYDFIVKGSCFCNGHADQCLPVEGFRPVKAPGAFHVVHGKCMCKHNTAGSHCQHCAPLYNDRPWEAADGRTGAPNECRTCKCNGHADTCHFDINVWEASGNRSGGVCNNCQHNTEGQHCQRCKPGFYRDLRRPFSAPDACKACSCHPVGSAILPFSSVTFCDPSNGDCPCKPGVAGPHCDRCMVGYWGFGDYGCRPCDCAGSCDPLTGDCISSNADVDWYHEVPAFHSLHNKSEPGWEWEDEQGFSALRHSGKCECKEQVLGNPKAFCGMKYSYVLKIKILSAHDKGSHAEVNVKIKKVLQA-TKLKILRGKRTLYPESWTNRGCTCPILNPGLEYLVAGYEDVRTGRLIVNMKSFVQPWKPALGRRVMHILKRECVEH", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9JI33-1", "uniprot_id": "NET4_MOUSE", "id": "Q9JI33-1", "name": "Netrin-4", "aln": "MGSCARLLLLWGCSAVAAGLNGVAG--ANSRCEKACNPRMGNLALGRKLRADTMCGQNATELFCFYSENADLTCRQPKCDKCNAAHSHLAHPPSAMADSSFRFPRTWWQSAEDVHREKIQLDLEAEFYFTHLIMVFKSPRPAAMVLDRSQDFGKTWKPYKYFATNCSATFGLEDDVVKKGAICTSRYSNPFPCTGGEVIFRALSPPYDIENPYSAKVQEQLKITNLRVRLLKRQSCPCQINDLNAKPHHFMHYAVYDFIVKGSCFCNGHADQCLPVEGFRPIKAPGAFHVVHGRCMCKHNTAGSHCQHCAPLYNDRPWEAADGRTGAPNECRTCKCNGHADTCHFDVNVWEASGNRSGGVCNNCQHNTEGQHCQRCKPGFYRDLRRPFSAPDACKACSCHPVGSAILPFSSVTFCDPSNGDCPCKPGVAGPHCDRCMVGYWGFGDYGCRPCDCAGSCDPLTGDCISSNADVDWYHEVPAFHSMHNKSEPSWEWEDEQGFSALRHSGKCECKEQVLGNPKAFCGMKYSYVLKIKILSAHDKGSHAEVNVKIKKVLKS-TKLKILRGKRTLYPESWTNRGCTCPILNPGLEYLVAGHEDVRTGKLIVNMKSFVQHWKPALGRRVMHILKRDCV--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9HB63-1", "uniprot_id": "NET4_HUMAN", "id": "Q9HB63-1", "name": "Netrin-4", "aln": "MGSCARLLLLWGCTVVAAGLSGVAG--VSSRCEKACNPRMGNLALGRKLWADTTCGQNATELYCFYSENTDLTCRQPKCDKCNAAYPHLAHLPSAMADSSFRFPRTWWQSAEDVHREKIQLDLEAEFYFTHLIVMFKSPRPAAMVLDRSQDFGKTWKPYKYFATNCSATFGLEDDVVKKGAICTSKYSSPFPCTGGEVIFKALSPPYDTENPYSAKVQEQLKITNLRVQLLKRQSCPCQRNDLNEEPQHFTHYAIYDFIVKGSCFCNGHADQCIPVHGFRPVKAPGTFHMVHGKCMCKHNTAGSHCQHCAPLYNDRPWEAADGKTGAPNECRTCKCNGHADTCHFDVNVWEASGNRSGGVCDDCQHNTEGQYCQRCKPGFYRDLRRPFSAPDACKPCSCHPVGSAVLPANSVTFCDPSNGDCPCKPGVAGRRCDRCMVGYWGFGDYGCRPCDCAGSCDPITGDCISSHTDIDWYHEVPDFRPVHNKSEPAWEWEDAQGFSALLHSGKCECKEQTLGNAKAFCGMKYSYVLKIKILSAHDKGTHVEVNVKIKKVLKS-TKLKIFRGKRTLYPESWTDRGCTCPILNPGLEYLVAGHEDIRTGKLIVNMKSFVQHWKPSLGRKVMDILKRECK--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AB13A9Z0-1", "uniprot_id": "A0AB13A9Z0_DANRE", "id": "A0AB13A9Z0-1", "name": "", "aln": "---MSTMELTGRCVLLAALVMSVPHHACSGCVNRVCNPRMGNLAVGRPIQTVSQCGSTSPEQFCMYRPDS----CVLDCEICDASVSQHAHSPSSMTDSPFKQPLTWWQSAPGTAIETLQLDLEVEFYFTHLIIIFMSPRPAAMAIDRSRDFGQTWSLLMLFSHNCSEVSSLED-----GQRCTAKYSSAEPCTNGEVIYRALSP-YERLDPYSTDARSLLGVTNVRIRLLQPHSCPCPIADANAAT---PRYAISDLILKGGCLCHGHADQCVPTGGKHNSKTFG-KHVVHGKCLCRHHTAGDHCERCHRLYNDRPWRAADGLTGEANQCVECKCNGHAESCHFDESVWLRSGQQHGGVCD-CLHNTTGQHCQHCQSGFYRDPEKPSTAPDSCTPCMCNHVGS--------SYCKPDNGECVCKPGVAGRHCEQCMLGYWGLDEYGCKPCQCAGDCDPYTGDCMIRSESDD------------NSTAENHLFRTEELFSALSHPDKCICKQQALGNSKVFCNAKYAYAVKVRVLGAHDKGSHAEVDVKILKVLWDNTRLRLSRGSRTLYPESWMSRGCTCPVLFPGLEYLVVGHEDVRKGRPVVNMKSIVKPWRASLSRKVHQLLKTKCS--", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : * * :** . .*. .. ::.*********:** : : : **..:.* :*:* :: .*: *:.: .: ** **:*:**.*: * ****** .. *.:*****.********::* *******.:***:***:**. *: *** . .*** * **::**.. ***.****::**** *: :***:..:. * :**:*::**: :**** * * . :**: *:*:**.*:*:******:*. * : *: * *:***:*:*:*:***.**::* *******.**** ** .*:* *******::**** .** **:: ****: * *** **:**:*:.***** .:* :***:*..* *: *** ::*.*.**:* ******* :*::**:****:.:***:**:***.*** ****: . * *.: :. : **** *..** **:*.***.*.**. **:*.:*:::*.*****:*.**:*** *** *:*:: **.******** .******:* *******.*:**:*.*: :*****:*: *:.:*.*:* .:** .* ", "identical_positions": 311, "similar_positions": 170, "identity": "49.13%" }, { "cls_id": "homologset.agr.MGI:1888981", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q5U1X1-1", "uniprot_id": "ORN_RAT", "id": "Q5U1X1-1", "name": "Oligoribonuclease, mitochondrial", "aln": "MLGVSLGARLLRGVGG-------RRG-QFGARGVSEGSAAMAAG----ESMAQRMVWVDLEMTGLDIEKDQIIEMACLITDSDLNILAEGPN-------LIIKQPDELLDSMSDWCKEHHGKSGLTKAVKESTVTLQQAEYEFLSFVRQQTP-PGLCPLAGNSVHADKKFLDKHMPQFMKHLHYRIIDVSTVKELCRRWYPEDYEFAPKKAASHRALDDISESIKELQFYRNNIFKKKTDEKKRKIIENGENEKPVS------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9D8S4-1", "uniprot_id": "ORN_MOUSE", "id": "Q9D8S4-1", "name": "Oligoribonuclease, mitochondrial", "aln": "MLGVSLGARLLRGVGG-------RRG-QFGARGVSEGSAAMAAG----ESMAQRMVWVDLEMTGLDIEKDQIIEMACLITDSDLNILAEGPN-------LIIKQPDELLDSMSDWCKEHHGKSGLTKAVKESTVTLQQAEYEFLSFVRQQTP-PGLCPLAGNSVHADKKFLDKHMPQFMKHLHYRIIDVSTVKELCRRWYPEDYEFAPKKAASHRALDDISESIKELQFYRNNIFKKKTDEKKRKIIENGETEKPVS------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9Y3B8-1", "uniprot_id": "ORN_HUMAN", "id": "Q9Y3B8-1", "name": "Oligoribonuclease, mitochondrial", "aln": "MLGGSLGSRLLRGVGG-------SHG-RFGARGVREGGAAMAAG----ESMAQRMVWVDLEMTGLDIEKDQIIEMACLITDSDLNILAEGPN-------LIIKQPDELLDSMSDWCKEHHGKSGLTKAVKESTITLQQAEYEFLSFVRQQTP-PGLCPLAGNSVHEDKKFLDKYMPQFMKHLHYRIIDVSTVKELCRRWYPEEYEFAPKKAASHRALDDISESIKELQFYRNNIFKKKIDEKKRKIIENGENEKTVS------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VCI0-1", "uniprot_id": "ORN_DROME", "id": "Q9VCI0-1", "name": "RNA exonuclease 2", "aln": "MLAH------LRRVGL-------SLNRQIRSHIAFNSNDRMSST----CGLDTDIVWMDLEMTGLDIEKDKILEVACIITDQDLNVKSEGPC-------FAINHPQEVYDSMNEWCMKHHYNSGLIDRCKSSDVNLEEASNLVLSYLEKNIP-KRACPLGGNSVYTDRLFIMKFMPLVDAYLHYRIVDVSTIKELAKRWHPAILDSAPKKSFTHRSLDDIRESIKELAYYKANLFK---------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P54964-1", "uniprot_id": "ORN_YEAST", "id": "P54964-1", "name": "Oligoribonuclease, mitochondrial", "aln": "MKWLLFPARIVARTRPNLFSLYRRSVSQYLRPRTIQNLQSMAQTPELKTKLFKPLVWIDCEMTGLDHVNDRIIEICCIITDGHLAPVKAADGQGDSHYESVIHYGPEVMNKMNEWCIEHHGNSGLTAKVLASEKTLAQVEDELLEYIQRYIPDKNVGVLAGNSVHMDRLFMVREFPKVIDHLFYRIVDVSSIMEVARRHNPALQARNPKKEAAHTAYSDIKESIAQLQWYMDNYLKPPQETESVESIGSEQPESPSSSTSSLKRQRTDF", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* : . : . :. *: : :**:* ****** :*:*:*:.*:*** .* . *: *: :.*.:** :** :*** * .* :.. .*.::.: * *.****: *: *: : :* . :*.***:***:: *:.:* * *** :* : .** *** :* :* * :* ", "identical_positions": 64, "similar_positions": 57, "identity": "23.79%" }, { "cls_id": "homologset.agr.MGI:1888984", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZCM2-1", "uniprot_id": "D3ZCM2_RAT", "id": "D3ZCM2-1", "name": "T-box transcription factor TBX21", "aln": "MG-IVEPGCGDMLTGTEPIP-SDEGRGTGADQQHRFFYP-ESGAQDP----TDRRAVSSLGSSYSGSALVPAPPGRFLGAYAYPPRAQATGFP---GPGESFPPPAGAEGYPPVDGYAAPDPRAGLYPG------PREDYALPAGLEVSGKLRVALSNHLLWSKFNQHQTEMIITKQGRRMFPFLSFTVAGLEPTSHYRMFVDVVLVDQHHWRYQSGKWVQCGKAEGSMPGNRLYVHPDSPNTGAHWMRQEVSFGKLKLTNNKGASNNVTQMIVLQSLHKYQPRLHIVEVNDGEPEAACSAN-THIFTFQETQFIAVTAYQNAEITQLKIDNNPFAKGFRENFESMYTSVDTSVPSP-PGPNCQLLGG--DPYSPLLSNQYPVS---SRFYP--------DLPGQPKDMVSQSYWLGTPREP--------SYETEFRAVSV-KPTFLPSAPGTTVPYYR------GPDVLAPGAGWPMA----------PQYPPKMSPAGWFRTMRTLPMDPGLGSSEE-----------------QGS-----PSLWTEVTSLQ-PEPSDSGLGEG-DTKRRRISPYPSSGDSSSPAGAPSPFDKE--TEGQFYNYFPN", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9JKD8-1", "uniprot_id": "TBX21_MOUSE", "id": "Q9JKD8-1", "name": "T-box transcription factor TBX21", "aln": "MG-IVEPGCGDMLTGTEPMP-SDEGRGPGADQQHRFFYP-EPGAQDP----TDRRAGSSLGTPYSGGALVPAAPGRFLGSFAYPPRAQVAGFP---GPGEFFPPPAGAEGYPPVDGYPAPDPRAGLYPG------PREDYALPAGLEVSGKLRVALSNHLLWSKFNQHQTEMIITKQGRRMFPFLSFTVAGLEPTSHYRMFVDVVLVDQHHWRYQSGKWVQCGKAEGSMPGNRLYVHPDSPNTGAHWMRQEVSFGKLKLTNNKGASNNVTQMIVLQSLHKYQPRLHIVEVNDGEPEAACSASNTHVFTFQETQFIAVTAYQNAEITQLKIDNNPFAKGFRENFESMYASVDTSVPSP-PGPNCQLLGG--DPFSPLLSNQYPVP---SRFYP--------DLPGQPKDMISQPYWLGTPREH--------SYEAEFRAVSM-KPTLLPSAPGPTVPYYR------GQDVLAPGAGWPVA----------PQYPPKMSPAGWFRPMRTLPMDPGLGSSEE-----------------QGSS----PSLWPEVTSLQ-PEPSDSGLGEG-DTKRRRISPYPSSGDSSSPAGAPSPFDKE--TEGQFYNYFPN", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9UL17-1", "uniprot_id": "TBX21_HUMAN", "id": "Q9UL17-1", "name": "T-box transcription factor TBX21", "aln": "MG-IVEPGCGDMLTGTEPMPGSDEGRAPGADPQHRYFYP-EPGAQDA----DERRGGGSLGSPYPGGALVPAPPSRFLGAYAYPPRPQAAGFP---GAGESFPPPADAEGYQPGEGYAAPDPRAGLYPG------PREDYALPAGLEVSGKLRVALNNHLLWSKFNQHQTEMIITKQGRRMFPFLSFTVAGLEPTSHYRMFVDVVLVDQHHWRYQSGKWVQCGKAEGSMPGNRLYVHPDSPNTGAHWMRQEVSFGKLKLTNNKGASNNVTQMIVLQSLHKYQPRLHIVEVNDGEPEAACNASNTHIFTFQETQFIAVTAYQNAEITQLKIDNNPFAKGFRENFESMYTSVDTSIPSP-PGPNCQFLGG--DHYSPLLPNQYPVP---SRFYP--------DLPGQAKDVVPQAYWLGAPRDH--------SYEAEFRAVSM-KPAFLPSAPGPTMSYYR------GQEVLAPGAGWPVA----------PQYPPKMGPASWFRPMRTLPMEPGPGGSEG-----------------RGPEDQGPPLVWTEIAPIR-PESSDSGLGEG-DSKRRRVSPYPSSGDSSSPAGAPSPFDKE--AEGQFYNYFPN", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "D1YT98-1", "uniprot_id": "D1YT98_DANRE", "id": "D1YT98-1", "name": "", "aln": "MGGIGRNFYLNMLNGTDAQSFAKDAELSSHLHRHRDLSDFKMGIQDTRFYYQDSIPNGQESLTLPFHAEHHQSAGAQTGRFYAPAPLGSCHFTSRSGTGHTYVP-AGADAYSSANGKDVYPSSADGYTASFQHGFPRAPMYSLPGLQVSGKTQVLLNNYPLWAKFHKYQTEMIITKQGRRMFPFLSFNITSLDPSAHYNIYVDVVLADQHHWRYQGGKWVQCGKAEGNMPGNRMYMHPDSPNTGTHWMRQEVSFGKLKLTNNKGSSNNVAQMIVLQSLHKYQPRLHIVEVKEDGTEDPFLTSKTQTFVFPETQFIAVTAYQNADITQLKIDHNPFAKGFRDNYDTLYAPPDPDRLTPSPTESQQLLSGSCYPHQPYLSDQYMSPLPQSRFYSREPVSMTQPCPKDPTSSPHSRWYLSSQQAVPPNRLDFSAYETEYTSNSLYKPFPLQSSPHHPLSYYSENPFTSGAVSSANPGAWTASGRPSPQYLNHPHHSKPTSSLSWFRAVPSPAASSSPTATNSRFHASPSLLEPQRQPLLQDKSKESTEDTWIEAPSVKSVDSADSGLFEGGESKKRRVSPYTSSTENSPPNRSAETCEKDNCSDAGYYGFYTH", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "** * . :**.**:. . :.:.. .. :** : : * **. : .. . . . * ... * : *. *. *.*. : * *.*:.* . :* . . *. *.. ** .**:**** :* *.*: **:**:::*******************.::.*:*::**.::*****.********.***********.*****:*:********:*******************:****:********************::. .* . :. *: *.* *************:*******:********:*::::*:. *.. :* * . *:*.* ..* *.:** . ****. * :... . ::*.: : :**:*: : *: ** * *:* .:.** * * ..*. : *::. .. .***.: : . ... .:: :. * * ..:: :.:**** ** ::*:**:***.** :.*.* :... :*: ::. :*.::.:", "identical_positions": 232, "similar_positions": 170, "identity": "38.03%" }, { "cls_id": "homologset.agr.MGI:1888986", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q62936-1", "uniprot_id": "DLG3_RAT", "id": "Q62936-1", "name": "Disks large homolog 3", "aln": "------------------------------------------MHKHQHCCKCPECYEVTRLAALRRLEPPGYGDWQVPDPYGPSG------GNGASSGYGGYSSQTLPSQAGATPTPRTKAKLIPTGRDVGPVPPKPVPG------------------KNTPKLNGSGP--SWWPECTCTNRDWYEQASPAPLLVNPEALEPSLSVNGSDGMFKYEEIVLERGNSGLGFSIAGGIDNPHVPDDPGIFITKIIPGGAAAMDGRLGVNDCVLRVNEVDVSEVVHSRAVEALKEAGPVVRLVVRRRQPPPET-------------------IMEVNLLKGPKGLGFSIAGGIGNQHIPGDNSIYITKIIEGGAAQKDGRLQIGDRLLAVNN----TNLQDVRHEEAVASLKNTSDMVYLKVAKPGSLHLNDMYAPPDYAS------TFTALADNHISHNSSLGYLGAVESKVTYPAPPQVPP-TRYS---------PIPRHMLAEEDFT-------------------------------------------------REPRKIILHKGSTGLGFNIVGGEDGEGIFVSFILAGGPADLSGELRRGDRILSVNGVNLRNATHEQAAAALKRAGQSVTIVAQYRPEEYSRFESKIHDLREQMMNSSMSSGSGSLRTSEKRSLYVRALFDYDRTRDSCLPSQGLSFSYGDILHVINASDDEWWQARLVTPHGESEQIGVIPSKKRVEKKERARLKTVKFHARTGMIESNRDFPGLSDDYYGAKNLKG----------------------------VTSNTSDSESSSKGQEDAILSYEPVTRQEIHYARPVIILGPMKDRVNDDLISEFPHKFGSCVPHTTRPRRDNEVDGQDYHFVVSREQMEKDIQDNKFIEAGQFNDNLYGTSIQSVRAVAERGKHCILDVSGNAIKRLQQAQLYPIAIFIKPKSIEALMEMNRRQTYEQANKIFDKAMKLEQEFGEYFTAIVQGDSLEEIYNKIKQIIEDQSGHYIWVPSPEKL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P70175-1", "uniprot_id": "DLG3_MOUSE", "id": "P70175-1", "name": "Disks large homolog 3", "aln": "------------------------------------------MHKHQHCCKCPECYEVTRLAALRRLEPPGYGDWQVPDPYGPSG------GNGASSGYGGYSSQTLPSQAGATPTPRTKAKLIPTGRDVGPVPPKPVPG------------------KSTPKLNGSGP--GWWPECTCTNRDWYEQASPAPLLVNPEALEPSLSVNGSDGMFKYEEIVLERGNSGLGFSIAGGIDNPHVPDDPGIFITKIIPGGAAAMDGRLGVNDCVLRVNEVDVSEVVHSRAVEALKEAGPVVRLVVRRRQPPPET-------------------IMEVNLLKGPKGLGFSIAGGIGNQHIPGDNSIYITKIIEGGAAQKDGRLQIGDRLLAVNN----TNLQDVRHEEAVASLKNTSDMVYLKVAKPGSIHLNDMYAPPDYAS------TFTALADNHISHNSSLGYLGAVESKVTYPAPPQVPP-TRYS---------PIPRHMLAEEDFT-------------------------------------------------REPRKIILHKGSTGLGFNIVGGEDGEGIFVSFILAGGPADLSGELRRGDRILSVNGVNLRNATHEQAAAALKRAGQSVTIVAQYRPEEYSRFESKIHDLREQMMNSSMSSGSGSLRTSEKRSLYVRALFDYDRTRDSCLPSQGLSFSYGDILHVINASDDEWWQARLVTPHGESEQIGVIPSKKRVEKKERARLKTVKFHARTGMIESNRDFPGLSDDYYGAKNLKG----------------------------VTSNTSDSESSSKGQEDAILSYEPVTRQEIHYARPVIILGPMKDRVNDDLISEFPHKFGSCVPHTTRPRRDNEVDGQDYHFVVSREQMEKDIQDNKFIEAGQFNDNLYGTSIQSVRAVAERGKHCILDVSGNAIKRLQQAQLYPIAIFIKPKSIEALMEMNRRQTYEQANKIFDKAMKLEQEFGEYFTAIVQGDSLEEIYNKIKQIIEDQSGHYIWVPSPEKL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q92796-1", "uniprot_id": "DLG3_HUMAN", "id": "Q92796-1", "name": "Disks large homolog 3", "aln": "------------------------------------------MHKHQHCCKCPECYEVTRLAALRRLEPPGYGDWQVPDPYGPGG------GNGASAGYGGYSSQTLPSQAGATPTPRTKAKLIPTGRDVGPVPPKPVPG------------------KSTPKLNGSGP--SWWPECTCTNRDWYEQ------------------VNGSDGMFKYEEIVLERGNSGLGFSIAGGIDNPHVPDDPGIFITKIIPGGAAAMDGRLGVNDCVLRVNEVDVSEVVHSRAVEALKEAGPVVRLVVRRRQPPPET-------------------IMEVNLLKGPKGLGFSIAGGIGNQHIPGDNSIYITKIIEGGAAQKDGRLQIGDRLLAVNN----TNLQDVRHEEAVASLKNTSDMVYLKVAKPGSLHLNDMYAPPDYAS------TFTALADNHISHNSSLGYLGAVESKVSYPAPPQVPP-TRYS---------PIPRHMLAEEDFT-------------------------------------------------REPRKIILHKGSTGLGFNIVGGEDGEGIFVSFILAGGPADLSGELRRGDRILSVNGVNLRNATHEQAAAALKRAGQSVTIVAQYRPEEYSRFESKIHDLREQMMNSSMSSGSGSLRTSEKRSLYVRALFDYDRTRDSCLPSQGLSFSYGDILHVINASDDEWWQARLVTPHGESEQIGVIPSKKRVEKKERARLKTVKFHARTGMIESNRDFPGLSDDYYGAKNLK------------------------------------------GQEDAILSYEPVTRQEIHYARPVIILGPMKDRVNDDLISEFPHKFGSCVPHTTRPRRDNEVDGQDYHFVVSREQMEKDIQDNKFIEAGQFNDNLYGTSIQSVRAVAERGKHCILDVSGNAIKRLQQAQLYPIAIFIKPKSIEALMEMNRRQTYEQANKIYDKAMKLEQEFGEYFTAIVQGDSLEEIYNKIKQIIEDQSGHYIWVPSPEKL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9QGS1-1", "uniprot_id": "A0A8M9QGS1_DANRE", "id": "A0A8M9QGS1-1", "name": "", "aln": "------------------------------------------MHKHHHCCKCPECYEVTRMAALRRMDAPAYGEWQ-PEPYGYPA------GYGGGQTLPPQTSGGGGGMGGGGTLGRSKGKMMSAGGPGGPNPKSQSKG------------------GPKVNGNNSGGQGGWWPECTCSNRDWYDQANPPPIIVNADSLDAGPYVNGSDGMYKYEEIILERGNSGLGFSIAGGMDNPHIPDDPGIFITKIIPGGAAAMDGRLGVNDCVLRVNDVDVSEVVHSKAVEALKEAGPVVRLLVRRRQAPPET-------------------ILEVNLLKGPKGLGFSIAGGIGNQHIPGDNSIYITKIIEGGAAQKDGRLQTGDRLLAVNN----IILQDVRHEEAVAALKNTSDMVYLKVAKPGPVHLNDMYAPPDYSSSLGLPPAFPTMVDNHVGHNSSMAYMGGMEPKPVY-QPPQVTP-SRYS---------PVPRHMLGEEDFTRAEPIYSAIHKPHGDTSPPSPHLCSRGSGDVGCSPAPPALCQSLVPYTGREPRKILLHKGSTGLGFNIVGGEDGEGIFVSFILAGGPADLSGELRRGDRILSVNGVNLRNATHEQAAAALKRAGQTVTIIAQYRPEEYSRFESKIHDLREQMMNSSMSSGSGSLRTSEKRSLYVRALFDYDRTRDSCLPSQGLSFSYGDILHVINASDDEWWQARLVTPHGESEQIGVIPSKKRVEKKERARLKTVKFHARTGMIESNREMFGRMNDIRPVKVKRKKSFNLSRKFPFYKSKENIVQELVETEQCLTSNTSDSESSSKGQEDTILSYEPVIRQEIHYTRPVIILGPMKDRVNDDLISEFPHKFGSCVPHTTRPRRENEMDGQDYHFVGSREQMEKDIQDNKFIEAGQFNENLYGTSILSVRAVAERGKHCILDVSGNAIKRLQQAQLYPIAIFIKPKSVEALMELNKRQTYEQANKVFDKAMKLEQEFGEFFTAIVQGDSLDEIYNKIKLIIEEQSGPYIWIPSAEKL", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P31007-2", "uniprot_id": "DLG1_DROME", "id": "P31007-2", "name": "Disks large 1 tumor suppressor protein", "aln": "MPVKKQEAHRALELLEDYHARLSEPQDRALRIAIERVIRIFKSRLFQALLDIQEFYELTLLDDSKSIQQKTAETLQIATKWEKDGQAVKIADFIKSSNLNRNCAYEFNNDASSNQTNQSALNQNPIANNVSAQAQAEALSRTFKSELEEILNQRMRIESDTENAKEPTVEQQQKQQQAQQRSSRSPQQQNPQQQQGSKSRSGSQTVNGDD-SWLYEDIQLERGNSGLGFSIAGGTDNPHIGTDTSIYITKLISGGAAAADGRLSINDIIVSVNDVSVVDVPHASAVDALKKAGNVVKLHVKRKRGTATTPAAGSAAGDARDSAASGPKVIEIDLVKGGKGLGFSIAGGIGNQHIPGDNGIYVTKLMDGGAAQVDGRLSIGDKLIAVRTNGSEKNLENVTHELAVATLKSITDKVTLIIGKTQHLTTSASGGGGGGLSS----GQQLSQSQSQLATSQSQSQVHQQQHATPMVNSQSTEPGSRYASTNVLAAVPPGTPRAVSTEDIT-------------------------------------------------REPRTITIQKGPQGLGFNIVGGEDGQGIYVSFILAGGPADLGSELKRGDQLLSVNNVNLTHATHEEAAQALKTSGGVVTLLAQYRPEEYNRFEARIQELKQQAALGAGGSGT-LLRTTQKRSLYVRALFDYDPNRDDGLPSRGLPFKHGDILHVTNASDDEWWQARRVLGDNEDEQIGIVPSKRRWERKMRARDRSVKFQGHAAANNNLDKQSTLDRKKKNFTFSRKFP--------FMKSRDEKNEDGSDQEPFMLCYTQDDANAEGASEENVLSYEAVQRLSINYTRPVIILGPLKDRINDDLISEYPDKFGSCVPHTTRPKREYEVDGRDYHFVSSREQMERDIQNHLFIEAGQYNDNLYGTSVASVREVAEKGKHCILDVSGNAIKRLQVAQLYPVAVFIKPKSVDSVMEMNRRMTEEQAKKTYERAIKMEQEFGEYFTGVVQGDTIEEIYSKVKSMIWSQSGPTIWVPSKESL", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : .: . * **:* : : :: * . : . . . : . ... :: : . . .. . . . : : . : : . . * ***.* : **:* *************** ****: *..*:***:*.***** ****.:** :: **:*.* :* *: **:***:** **:* *:*:: .. * ::*::*:** ********************.**:**:::***** ****. **:*:**.. *::* ** ***:**. :* * * :.*. : . . . * : :.::. ..* . : : . .. * :**: * . : :. **:* ****.* ::**. ************:**:************..**:***::****.*** :****:** *** :* **::********.***::*::*::* .: .**: ***::************* .**. ***:**.*.:****** *********** * ..*.****::***:* *:* *** ::***:.::. :. . . . : ..*: :****.* * .*:*:********:***:*******:*.************:*: *:**:***** ******:***:: ******:*:******: *** ***:***************** *****:*:******::::**:*:* * ***:* :::*:*:******:**.:****:::***.*:* :* .*** **:** *.*", "identical_positions": 408, "similar_positions": 214, "identity": "39.5%" }, { "cls_id": "homologset.agr.MGI:1888992", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q61468-1", "uniprot_id": "MSLN_MOUSE", "id": "Q61468-1", "name": "Mesothelin", "aln": "MALPTARPLLGSCGSPICSRSFLLLLLSLGWIPRLQTQTTKTSQEATLLHAVNG-AADFASLPTGLFLGLTCEEVSDLSMEQAKGLAMAVRQKNITLRGHQLRCLARRLPRHLTDEELNALPLDLLLFLNPAMFPGQQACAHFFSLISKANVDVLPRRSLERQRLLMEALKCQGVYGFQVSEADVRALGGLACDLPGKFVARSSEVLLPWLAGCQGPLDQSQEKAVREVLRSGRTQYGPPSKWSVSTLDALQSLVAVLDESIVQSIPKDVKAEWLQHISRDPSRLGSKLTVIHPRFRRDAEQKACPPGKEPYKVDEDLIFYQNWELEACVDGTMLARQMDLVNEIPFTYEQLSIFKHKLDKTYPQGYPESLIQQLGHFFRYVSPEDIHQWNVTSPDTVKTLLKVSKGQKMNAQAIALVACYLRGGGQLDEDMVKALGDIPLSYLCDFSPQDLHSVPSSVMWLVGPQDLDKCSQRHLGLLYQKACSAFQNVSGLEYFEKIKTFLGGASVKDLRALSQHNVSMDIATFKRLQVDSLVGLSVAEVQKLLGPNIVDLKTEEDKSPVRDWLFRQHQKDLDRLGLGLQGGIPNGYLVLDFNVREAFSSRASLLGPGFVLIWIPALLPALRLS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9ERA7-1", "uniprot_id": "MSLN_RAT", "id": "Q9ERA7-1", "name": "Mesothelin", "aln": "MALPTAQPLLGSCGSPICSRSFLLLLLSLGWLPLLQTQTTRTSQEAALLHAVTG-TVDFASLPTGLFLGLMCDEVSGLSMGHAKELAMAVRQKNIVLQVHQLRCLARRLPKHLTNEELDALPLDLLLFLNPAMFPGQQACAHFFSLISKANVNVLPRRSLERQRLLTGALKCQGVYGFQVSETDARALGGLACDLPGEFVAKSSEVLLPWLARCGGPLDQGQAKAVREVLRSGRAPYGPPSTWSVSTLDALQGLLVVLDESIVHSIPKDVITEWLQGISREPSRLGSKWTVTHPRFRRDTEQKACPPGKEPNVVDENLIFYQNWELEACVDGTLLAGQMDLVNEIPFTYEQLSIFKHKLDKTYPQGYPESLIKQLGHFFRYVSPEDIRQWNVTSPDTVNTLLKVSKGQKMDAQVIALVACYLRGGGKLDEDIVKALDNIPLSYLCDFSPQDLHAIPSSVMWLVGLHDLDKCSQRHLGILYQKACSAFQNVSGLEYFEKIRTFLGGASREDLRALSQHNVSMDIATFKKLQVDALVGLSVAEVQKLLGPHIGDLKTEEDKSPVRDWLFRQQQKDLDSLGLGLQGGIPNGYLILDFNVREAFSSGAPLLGPGFVFAWIPALLSALRLS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q13421-3", "uniprot_id": "MSLN_HUMAN", "id": "Q13421-3", "name": "Mesothelin", "aln": "MALPTARPLLGSCGTPALG-SLLFLLFSLGWVQPSRTLAGETGQEAAPLDGVLANPPNISSLSPRQLLGFPCAEVSGLSTERVRELAVALAQKNVKLSTEQLRCLAHRLSE--PPEDLDALPLDLLLFLNPDAFSGPQACTRFFSRITKANVDLLPRGAPERQRLLPAALACWGVRGSLLSEADVRALGGLACDLPGRFVAESAEVLLPRLVSCPGPLDQDQQEAARAALQGGGPPYGPPSTWSVSTMDALRGLLPVLGQPIIRSIPQGIVAAWRQRSSRDPSWRQPERTILRPRFRREVEKTACPSGKKAREIDESLIFYKKWELEACVDAALLATQMDRVNAIPFTYEQLDVLKHKLDELYPQGYPESVIQHLGYLFLKMSPEDIRKWNVTSLETLKALLEVNKGHEMSPQVATLIDRFVKGRGQLDKDTLDTLTAFYPGYLCSLSPEELSSVPPSSIWAVRPQDLDTCDPRQLDVLYPKARLAFQNMNGSEYFVKIQSFLGGAPTEDLKALSQQNVSMDLATFMKLRTDAVLPLTVAEVQKLLGPHVEGLKAEERHRPVRDWILRQRQDDLDTLGLGLQGGIPNGYLVLDLSMQEALSGTPCLLGPGPVLT-VLALLLASTLA", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "******:*******:* . *:*:**:****: :* : .*.***: *..* . . :::**.. :**: * ***.** :.: **:*: ***: * .******:**.. . *:*:************ *.* ***::*** *:****::*** : ****** ** * ** * :**:*.************.***.*:***** *. * *****.* :*.* .*:.* . *****.*****:***:.*: **.:.*::***:.: : * * **:** .: *: :*****:.*:.***.**:. :**.****::********.::** *** ** ********.::*****: ********:*::**::* :*****::***** :*:::**:*.**::*..*. :*: :::* *:**:* :.:* : .***.:**::* ::*.* :* * :***.*. *:*.:** ** ****:.* *** **::*****. :**:****:*****:*** :*:.*::: *:**********:: .**:** : *****::**:*.*** **************:**:.::**:*. . ***** *: : *** * *:", "identical_positions": 348, "similar_positions": 176, "identity": "55.59%" }, { "cls_id": "homologset.agr.MGI:1888993", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "B1WC49-1", "uniprot_id": "B1WC49_RAT", "id": "B1WC49-1", "name": "Apoptosis inhibitor 5", "aln": "-MPTVEELYRNYGILADATEQVGQHKDAYQVILDGVKGGTKEKRLAAQFIPKFFKHFPELADSAINAQLDLCEDEDVSIRRQAIKELPQFATG--ENLPRVADILTQLLQTDDSAEFNLVNNALLSIFKMDAKGTLGGLFSQILQGEDIVRERAIKFLSTKLKTLPDEVLTKEVEELILTESKKVLEDVTGEEFVLFMKILSGLKSLQTVSGRQQLVELVAEQADLEQT---FSPSDPDCVDRLLQCTRQAVPLFSKNVHSTRFVTYFCEQVLPN--LSTLTTPVEGLDIQLEVLKLLAEMSSFCGDMEKLETNLRKLFDKLLEYMPLPPEEAENGENAGNEEPKLQFSYVECLLYSFHQLGRKLPDFLTAKLNAEKLKDFKIRLQYFARGLQVYIRQLRLALQGKTGEALKTEENKIKVVALKITNNINVLIKDLFHIPPSYKSTVTLSWKPVQK----VEIGQKRTS-EDTSSGSPPKKSPG-GPKRDAR-----QIYNPPSGKYSSNLGN-FNYEQRGAFRGSRGGRGWGTRGNRSRGRLY", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9BZZ5-4", "uniprot_id": "API5_HUMAN", "id": "Q9BZZ5-4", "name": "Apoptosis inhibitor 5", "aln": "-MPTVEELYRNYGILADATEQVGQHKDAYQVILDGVKGGTKEKRLAAQFIPKFFKHFPELADSAINAQLDLCEDEDVSIRRQAIKELPQFATG--ENLPRVADILTQLLQTDDSAEFNLVNNALLSIFKMDAKGTLGGLFSQILQGEDIVRERAIKFLSTKLKTLPDEVLTKEVEELILTESKKVLEDVTGEEFVLFMKILSGLKSLQTVSGRQQLVELVAEQADLEQT---FNPSDPDCVDRLLQCTRQAVPLFSKNVHSTRFVTYFCEQVLPN--LGTLTTPVEGLDIQLEVLKLLAEMSSFCGDMEKLETNLRKLFDKLLEYMPLPPEEAENGENAGNEEPKLQFSYVECLLYSFHQLGRKLPDFLTAKLNAEKLKDFKIRLQYFARGLQVYIRQLRLALQGKTGEALKTEENKIKVVALKITNNINVLIKDLFHIPPSYKSTVTLSWKPVQK----VEIGQKRAS-EDTTSGSPPKKSSA-GPKRDAR-----QIYNPPSGKYSSNLGN-FNYEQRGAFRGSRGGRGWGTRGNRSRGRLY", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "O35841-1", "uniprot_id": "API5_MOUSE", "id": "O35841-1", "name": "Apoptosis inhibitor 5", "aln": "-MPTVEELYRNYGILADATEQVGQHKDAYQVILDGVKGGTKEKRLAAQFIPKFFKHFPELADSAINAQLDLCEDEDVSIRRQAIKELPQFATG--ENLPRVADILTQLLQTDDSAEFNLVNNALLSIFKMDAKGTLGGLFSQILQGEDIVRERAIKFLSTKLKTLPDEVLTKEVEELILTESKKVLEDVTGEEFVLFMKILSGLKSLQTVSGRQQLVELVAEQADLEQA---FSPSDPDCVDRLLQCTRQAVPLFSKNVHSTRFVTYFCEQVLPN--LSTLTTPVEGLDIQLEVLKLLAEMSSFCGDMEKLETNLRKLFDKLLEYMPLPPEEAENGENAGNEEPKLQFSYVECLLYSFHQLGRKLPDFLTAKLNAEKLKDFKIRLQYFARGLQVYIRQLRLALQGKTGEALKTEENKIKVVALKITNNINVLIKDLFHIPPSYKSTVTLSWKPVQK----VEIGQKRTS-EDTSSGSPPKKSPG-GPKRDAR-----QIYNPPSGKYSSNLSN-FNYER--SLQGK------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "R4GDP5-1", "uniprot_id": "R4GDP5_DANRE", "id": "R4GDP5-1", "name": "", "aln": "MAATVEELYRNYGILADAKEDLSTHKDAYQVILDGVKGGAKEKRLAAQFIPKFFSSFPELADAAINAQLDLCEDEDVSIRRQAIKELPRFASG--ENLPRVADILTQLLQTDDSAEFNQVNTALISIFKIDAKGTLGGLFSQILQGEDIVRERAIKFLSTKLKTMPEDIMTKEVEDYIFVETKKVLEDVTGEEFVLLMRILSGLKSMQTVSGRQQLVELVVEQAFLEQA---LNPADTDSVDRLLQCTRQALPLFSKNVHSTRFVTYFCEFVLPN--LSQLTSPVAELDIQLEVLKLLAEMSPYCGDMDKLEVNLNMLFEKLLEFMPLPPEE-ENGENAANEEPKLQFSYVECLLFSFHQLGKKLPDFLIDKVSAEKLKDFKIRLQYFARGLQVYIRQLRVALQGKTGDALKTDENKIKVVALKITNNINVLIKDLFHNPPSYKSTVTLSWKPVQKTEAAAAIGQKRRSGEDIGATATTKKHPTNLPRRDAR-----QIYNPPSGKYSASIGN-FSYEQRGGFRGGRG-RGFGGRGNRSRGRIY", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9V431-1", "uniprot_id": "API5_DROME", "id": "Q9V431-1", "name": "Apoptosis inhibitor 5 homolog", "aln": "-MDNIERLYKCYEILSEAGDKISEHVDEYKEILKAVKGTSKEKRLASQFIGNFFKHFPDLADTAIDAQFDLCEDDDTQIRRQAIKDLPKLCQGNADATIRVGDTLAQLLILDDPTELQQVNNSLLAIIKLDTKSSIAGLFQQISTGDETTRERCLKFIATKLLTMGPTVITKEIEDYIVEEIKKALQDVTADEFHLCMTILGATKLGSTITGHAELVKLATEQAELNNTDADIIAVDDEVVERFIQCASAAAPYFSKTIKSTAFVAHVCDKLLPIKTWNMIATAVSQDQIQLRLLKVFAEMITNTDKLDNASERINAVYNVLLEYMPLPKLS---DEDLGDTPPSFQFSHAECLLYALHTLGKNHPNSLSFVEDAEKLKDFRARLQYLARGTQGYIKKLEESLKGKTGEELKTEENQLKQTALKTTSNINILIRDLFHSPPIFKHDIVLSWIVPKN----NKLGKRHAPITFGEKAAANGKDKDQEPEKKSRPSNDQKFYSPPSGKYSNKVNQSYGNNNRTRQRGGGGGGGSGGGYRNRRFNKY", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .:*.**: * **::* :.:. * * *: **..*** :******:*** :**. **:***:**:**:*****:*..*******:**::. * : **.* *:*** **.:*:: **.:*::*:*:*:*.::.***.** *:: .***.:**::*** *: ::***:*: *. * **.*:***.:** * * **.. * .*::*: :**:*..*** *::: : . * : *:*::**: * * ***.::** **::.*: :** . :::.* :***.:**::*** . ..::: . .:. ::: ***:**** . .*: .: *.:***:.****:::* **:: *: * .*******: ****:*** * **::*. :*:****: ***:**::* .*** *.***:**:**** ** :* :.*** :: :*::: . :. * *.:.:* ::*.******* .:.: :. :. :* ", "identical_positions": 219, "similar_positions": 175, "identity": "40.26%" }, { "cls_id": "homologset.agr.MGI:1888994", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I5ZYX6-1", "uniprot_id": "A0A8I5ZYX6_RAT", "id": "A0A8I5ZYX6-1", "name": "", "aln": "-------------------------------MGN---AAGSAEQPAGPTAS------------PPKQPAV---PKQPMPAAGELEERFTRVLNCMNLPPDKVQLLSQYDNEKKWELICDQERFQVKNPPAAYIQKLKS-YLDTGGVSRKVATDWMSNLGFKRRVQEST--QVLRELETSLRTNHIGWVQEFLNEENRGLDVLLEYLAFAQ---------CSVAYDMESTENVASGTEKNKPLEQSVEDLSK---------------APPSSVPKSR-LTIKCP-------PSPRLTPAHSRKALRNSRIVS--QKDDVHVCIMCLRAIMNYQSGFSLVMNHPACVNEIALSLNNKNPRTKALVLELLAAVCLVRGGHDIILAAFDNFKEVCGEQHRFEKLMEYFRN-EDSNIDFMVACMQFINIVVHSVENMNFRVFLQYEFTHLGLDLYLERLRLTESDKLQVQIQAYLDNVFDVGTLLEETETKNAVLEHMEELQEQVATLTERLRDTENDSMAKIAELEKQ---LSQARKELETLRERFSESTPMVTSR------------RIPEPEKVPAPTVVR-------PSALELKVEELEEKGLIRILRGPGDVVSIEILPGAAATPSGDDAPAPRVSTDSPSTAESVPEAASPTPPPPPPPPPPLPNLQSQQEALPSAPPLAPPLPGCAAPPPAPPLPGDLPPPPPPPP--LGTDGPVPPPPPPPP---GGPPDILGGQDPEIGPGVKAKKPIQTKFRMPLLNWVALKPSQITGTVFTELNDEKVLQELDMNDFEEQFKTKSQGPSLDIS-------ALKGKTAHKAPTKATLIEANRAKNLAITLRKGNLGADRICEAIETYDLQTLSLDFLELLTRFLPTDYERSLIARFEKEQRPMEELSEEDRFMLRFSRIQRLPERMNTLTFLGNFPDTAQLLMPQLNAIIAASISIKSSDKLRQILEIVLAFGNYMNSSKRGAAYGFRLQSLDALLEMKSTDRKQTLLHYLVKVIAEKYPQLTGFHSDLHFLDKAGSVSLDSVLGDVRSLQRGLELTQREFVRQDD---CLVLKEFLRANSPTMDKLLADSKTAQEAYESVVEYFGENPKTTSPSMFFSLFSRFTKAYKKAEQEVEQWKKEAAA-----DTSGR---------EEPPAPKSPPKARRQQMDLISELKRK----QLKEPLIYESDRDGAIEDIITVLKTVPFT-ARTGKRTSRLLCEAS---LGEEMTL-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9JL26-1", "uniprot_id": "FMNL1_MOUSE", "id": "Q9JL26-1", "name": "Formin-like protein 1", "aln": "-------------------------------MGN---AAGSAEQPAGPTAS------------PPKQPAV---PKQPMPAAGELEERFTRVLNCMNLPPDKVQLLSQYDNEKKWELICDQERFQVKNPPAAYIQKLKS-YLDTGGVSRKVASDWMSNLGFKRRVQEST--QVLRELETSLRTNHIGWVQEFLNEENRGLDVLLEYLAFAQ---------CSVAYDMESTDSVASGAEKSKPLDQSVEDLSK---------------APPSSVPKSR-LTIK-------------LTPAHSRKALRNSRIVS--QKDDVHVCIMCLRAIMNYQSGFSLVMNHPACVNEIALSLNNKSPRTKALVLELLAAVCLVRGGHDIILAAFDNFKEVCGEQHRFEKLMEYFRH-EDSNIDFMVACMQFINIVVHSVENMNFRVFLQYEFTHLGLDLYLERLRLTESDKLQVQIQAYLDNVFDVGTLLEETETKNAVLEHMEELQEQVATLTERLRDTENDSMAKIAELEKQ---LSQARKELETLRERFSESTPMGTSR------------RIPEPEKVPVPTVVR-------PSALELKVEELEEKGLIRILRGPGDVVSIEILPGAAATPSGDDAQAPRVSTDSPSTAESIPEAASP-PPPPPPPPPPLPNLQSQQEAPPSAPPLAPPLPGCAEPPPAPPLPGDLPPPPPPPP--LGTDGPVPPPPPPPP---GGPPDILGGQGPDIGPGVKAKKPIQTKFRMPLLNWVALKPSQITGTVFTELNDEKVLQELDMNDFEEHFKTKSQGPCLDIS-------ALKGKASQKAPTKTILIEANRAKNLAITLRKGNLGADRICQAIETYDLQTLSLDFLELLTRFLPTDYERSLIARFEKEQRPMEELSEEDRFMLRFSRIQRLPERMNTLTFLGNFPDTAQLLMPQLNAIIAASMSIKSSDKLRQILEIVLAFGNYMNSSKRGAAYGFRLQSLDALLEMKSTDRKQTLLHYLVKVIAEKYPQLTGFHSDLHFLDKAGSVSLDSVLGDVRSLQRGLELTQREFVRQDD---CLVLKEFLRANSPTMDKLLADSKTAQEAYESVVEYFGENPKTTSPSMFFSLFSRFTKAYKKAEQEVEQWKKEAAA-----DTSGR---------EEPPTPKSPPKARRQQMDLISELKRK----QQKEPLIYESDRDGAIEDIITDLRNQPYIRADTGRRSARRRPPGPPLPVTTDLAL-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O95466-1", "uniprot_id": "FMNL1_HUMAN", "id": "O95466-1", "name": "Formin-like protein 1", "aln": "-------------------------------MGN---AAGSAEQPAGPAAP------------PPKQPAP---PKQPMPAAGELEERFNRALNCMNLPPDKVQLLSQYDNEKKWELICDQERFQVKNPPAAYIQKLKS-YVDTGGVSRKVAADWMSNLGFKRRVQEST--QVLRELETSLRTNHIGWVQEFLNEENRGLDVLLEYLAFAQ---------CSVTYDMESTDNGASNSEKNKPLEQSVEDLSK---------------GPPSSVPKSRHLTIK-------------LTPAHSRKALRNSRIVS--QKDDVHVCIMCLRAIMNYQSGFSLVMNHPACVNEIALSLNNKNPRTKALVLELLAAVCLVRGGHDIILAAFDNFKEVCGEQHRFEKLMEYFRN-EDSNIDFMVACMQFINIVVHSVENMNFRVFLQYEFTHLGLDLYLERLRLTESDKLQVQIQAYLDNIFDVGALLEDTETKNAVLEHMEELQEQVALLTERLRDAENESMAKIAELEKQ---LSQARKELETLRERFSESTAMGPSR------------RPPEPEKAPPAAPTR-------PSALELKVEELEEKGLIRILRGPGDAVSIEILPVAVATPSGGDAPTPGVPTGSPS--PDLAPAAEPAPGAAPPPPPPLPGLPSPQEAPPSAPPQAPPLPGSPEPPPAPPLPGDLPPPPPPPPPPPGTDGPVPPPPPPPPPPPGGPPDALGRRDSELGPGVKAKKPIQTKFRMPLLNWVALKPSQITGTVFTELNDEKVLQELDMSDFEEQFKTKSQGPSLDLS-------ALKSKAAQKAPSKATLIEANRAKNLAITLRKGNLGAERICQAIEAYDLQALGLDFLELLMRFLPTEYERSLITRFEREQRPMEELSEEDRFMLCFSRIPRLPERMTTLTFLGNFPDTAQLLMPQLNAIIAASMSIKSSDKLRQILEIVLAFGNYMNSSKRGAAYGFRLQSLDALLEMKSTDRKQTLLHYLVKVIAEKYPQLTGFHSDLHFLDKAGSVSLDSVLADVRSLQRGLELTQREFVRQDD---CMVLKEFLRANSPTMDKLLADSKTAQEAFESVVEYFGENPKTTSPGLFFSLFSRFIKAYKKAEQEVEQWKKEAAAQEAGADTPGK---------GEPPAPKSPPKARRPQMDLISELKRR----QQKEPLIYESDRDGAIEDIITVIKTVPFT-ARTGKRTSRLLCEAS---LGEEMPL-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0ACD6B6X1-1", "uniprot_id": "A0ACD6B6X1_DANRE", "id": "A0ACD6B6X1-1", "name": "", "aln": "-------------------------------MGN---AAGGLEQAEGQEAKGSTGGLNPAPSILKKKCAP---PKLPMPPEEELEERFNVVLSTMNLPPDKMKLLSQYDNEKKWELVCDQERFQVKNPPSAYLTKIKSFYQDQGGVTRR----------FKKRVQEST--QVLRELEISLRTNHIGWAQEFLNEENQGLDVLVDYLSYSQ---------SDVPFEVESVENGGSISDNRRMSERSVEDLAKN----------VNHSAPHTMTRAARALTVR------------ITSLAHSRKTLRIARLAT--QRDDVHLCIMCLRAIMNYQSGFNLVMTHPRCVNEITLSLNNKNPRTKALVLELLAAVCLVRGGHDIIISAFDNFKDASGEKNRFEKLMEYFMH-DDSNVDFMVACMQFINIVVHSVENMNFRVHLQYQFSQLGLDQYLESLKDMESEKLQVQIQAYLDNVFDVGALLEDAENKGDIVDLVADLQENNAQLTARLQECENGALDKIAELEQQ---LLQATKESALLKESLRESCTQVSTLQQREREREIQREREREQERQSQPSQVDREKGSEKESKLEKKLKELQEKGLLRLERTVSGSLDIDVIPVTLEKIVTQTVTVPDSASQAPP-----SPAAAP---PPPPPPPPLPGAEAPPPPPPPPPPSGS--GGAPPPPPPPPPPGGGPPPPPPPP---GSGPPPPPGAPPAP-------------GAETGP--KARKTIQTKFRMPLLNWQALKPNQVSGTVFSELNDEQVLEALNMDLFAEQFKTKAQGPPADLS-------KLKVKVAEKAPTKVSLLEANKAKNLAITLRKGGMNPDKICTAIESYD-QSLSLDFLELLERFIPSEYEMKLLQNYEKEGRPLEDLSEEDRFISRFGKIPRLSQRINTLTFMGNFPESIKRLQPQLDAIIAASVSLKSSSKLKKMLEIILAFGNYMNSSKRGAAYGFRLQSLDLLLDTKSTDRTQTLLHFIANMVHEKYPELTSFHNELRFVDKAALVSLDGVLQDVRSLERGMEGTKKEFMVQDD---IPALKEFVKANSDVLDSLVKDGKTAQEAYAAVVEYYGENPKTTQPSMFFPIFARFIKAYKQAEQDNEQKKKQEMAAEEQATPSPK---------KKEGTPQKGP--MMPKMDLIAELKKR----QVKP-----QVTDGAIDDIITDLRNSPYR-RGDGRRAAPRQEN-------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8M3APF0-1", "uniprot_id": "A0A8M3APF0_DANRE", "id": "A0A8M3APF0-1", "name": "", "aln": "-------------------------------MGN---AAGSLEMSPVREIKR------PLSTYGQKPPAA---PKLPQPSEEELEERFSIVLNSMNLPPDKVMLLSQYDSEKKWELVCDQERFQVKNPPSAYIQKLKS-VLEQGGGRK-----------FKRRVQEST--QVLRELEISLRTNHIGWAEEFLNEENNGLDVLVDYLSFAQ---------RAVIYDMDSS------SENGSFEEKSVEDLTT---------------SATNSPTHNSPRSAR---------------PFTTRKALRYSRMLS--QNNHLHLCIMCLRAIMNYQLGFNQVTAHPSCVNEITLSLNNRSARTKALVLELLAAVCLVRGGHEMILAAFNNFREVCGEKNRFEKLMEYFRN-EESNIDFMVACMQFINIVVHSVEDMNFRVFLQYEFTQLGLDSYLEKLNMTESERLQIQIQAYLDNVFDVGAMLEDAEAKNTLMEHLEELQEQNTQLNTRLHQCEIEALEKTTDLEQQ---LIQSSKQVELLKESVKEAQTQLQQLQLQ---------QQKDRQTRSETQQHTHTDRQQTQMQMEKMLQLLVERGLIRMERSASGALDLHIIAAANTTDKCSKETSP---------------------VPQSPPPPPVP----------------------------------APPPPPPPP-------PLALAPPTSP---------FIGRTGTIKTGVKGKQPIKTKYRMPLLNWQALMEEQVAGTVFTELDDQTVLQELNMDVFEELFKTKAQSAPVDVG-------TLKVKVAQKASSKISLLEPNRAKNLAITLRKAGMSTAQICTAIQTYNLELLKSDFLELLERFVPSDYELKLIQNYERSGRPLVELSEEDRFMMAFSKIPRLTQRISTLTFMGSFSESVLILKPQLNAVISASKSIRSSSKLKKILEIILAFGNYMNSGKRGSAYGFRLQSLDLLLDMKSTDRKQTLLHFIVSIIQDKYPQLSNFHTELHFLDKAALVSLDSVLSDVCSLQKGMDVVCKELEQQQN---SSVLTQFICTNRGLLDTLIKDSTTAQEAYQSVVEYFGENPKSTPPSAFFPVFTRFIKAYKLCEQEIDQRRKRLSDSEE--TADLK---------FSDAPVHRQKPLRLPQLDLISELKRR----QMSP--LVREGKDGAIEDIITDLRNQPYIRADGGRRSAKWKPAQQ-LAVSTDISL-", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VUC6-1", "uniprot_id": "FRL_DROME", "id": "Q9VUC6-1", "name": "Formin-like protein", "aln": "MGAVKSRTITSADVDADEQLQHPHSHAHHHSMRNGHQHNGSISSGTLQKQDLRYDIGCSSQYQHVRQPSLRSRSQQPMPTTDELDRRFAKVLASMDLPPDKAKLLRNYDDEKKWDMICDQEMVQAKDPPSHYLSKLRT-YLDPKASRSHRLYLFYFLCQKRKMVGESTSTQVLRDLEISLRTNHIEWVKEFLDDTNQGLDALVDYLSFRLQMMRHEQRLQGVLCASEERLNLTNGGDGGEIVMGNSSSVSPGGGGGLLSHGNSTGHGLANGTLDSRQQHTMSYGFLRPTIADALDSPSLKRRSRHIAKLNMGAATDDIHVSIMCLRAIMNNKYGFNMVIQHREAINCIALSLIHKSLRTKALVLELLAAICLVKGGHEIILGSFDNFKDVCQEKRRFQTLMEYFMNFEAFNIDFMVACMQFMNIVVHSVEDMNYRVHLQYEFTALGLDKYLERIRLTESEELKVQISAYLDNVFDVAALMEDSETKTSALERVQELEDQ----LEREIDRNSEFLYKYAELESESLTLKTEREQLAMIRQKLEEELTVMQRML-----------QHNEQELKKRDTLLH---------TKNMELQTLS-RSLPRSASSGDGSLANGGLMAGSTSGAASLTLPPPPPPMPAS-----PTASSAAPPPPPPPAPPAP------PPPPGFSPLGS---------PSGSLASTAPSPPHAPP------MLSSFQPPPPP---------VAGFMPAPDGAMTIKRKVPTKYKLPTLNWIALKPNQVRGTIFNELDDEKIFKQIDFNEFEERFKIGIGGALRNGSNGTEVDGSLQSSKRFKRPDNVSLLEHTRLRNIAISRRKLGMPIDDVIAAIHSLDLKKLSLENVELLQKMVPTDAEVKSYKEYIIERKDQQLLTEEDKFMLQLSRVERISSKLAIMNYMGNFVDSVHLISPQVQSIAGASTSLKQSRKFKAVLEIVLAFGNYLNSNKRGPAYGFKLQSLDTLIDTKSTDKRSSLLHYIVATIRAKFPELLNFESELYGTDKAASVALENVVADVQELEKGMDLVRKEAELRVKGAQTHILRDFLNNSEDKLKKIKSDLRHAQEAFKECVEYFGDSSRNADAAAFFALIVRFTRAFKQHDQENEQRLRLEKAAALAASKKENDQVLMRNKVNQKKQQLPSNGALSLQEAVINELKSKAHSVREKKLLQQDEVYNGALEDILLGLKSEPYRRADAVRRSQRRRIDNNRLSRTLEEMDC", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * * *. . : : .: * *. **:.** .* *:***** ** :**.****:::**** .*.*:**: *: *::: : . :: * *** ****:** ******* *.:***:: *.***.*::**:: * :. : . ..:: . . .*:: : ::: :.:*:.********* : **. * * .:* *:*** ::. ************:***:***::*:.:*:**::.. *:.**:.***** : : *:*********:********:**:**.***:*: **** *** :. **:.*::**.*****:***.:::*::* * :: : :*::: * : : : * ::**.: * :: ::: . * . : : : : :: * :.* * .. : : . * . .**.** * *.** .** . .*..* . :: : **:::* *** ** .*: **:*.**:*: ::: :::. * * ** .. : . *: . * . : *:* .: :*:**: ** .: : **.: : : * : :*** :::*:: * . .: . : *:***:*: :.:: *:..:: :.::*.* :: : **:::: .** *::.* *:: :***:******:**.***.****:***** *:: ****: .:***::. : *:*:* .*..:* ***. *:*:.*: ** .*::*:: . :* : . * :*: . :..: * ****: ***:*:..:.: .. **.:: ** :*:* :*: :* : . . : :* *** : : . . :**::**: ::. *: :*: ", "identical_positions": 312, "similar_positions": 313, "identity": "25.08%" }, { "cls_id": "homologset.agr.MGI:1888996", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P27274-1", "uniprot_id": "CD59_RAT", "id": "P27274-1", "name": "CD59 glycoprotein", "aln": "MRARRG--FILLLLL-AVLCSTGVSLRCYNCLDPVSSCKTNSTCSPNLDACLVAVSGKQVYQQCWRFSDCNAKFILSRLE-IANVQYRCCQADLCNKSFE--DKPNNGAISLLGKTALLVTS-VLAAILKPCF", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P58019-1", "uniprot_id": "CD59B_MOUSE", "id": "P58019-1", "name": "CD59B glycoprotein", "aln": "MRAQRG--LILLLLLLAVFCSTAVSLKCYNCLDPVSSCKINTTCSPNLDSCLYAVAGRQVYQQCWKLSDCNSNYIMSRLD-VAGIQSKCCQWDLCNKNLDGLEEPNNAETSSLRKTALLGTS-VLVAILKFCF", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P13987-1", "uniprot_id": "CD59_HUMAN", "id": "P13987-1", "name": "CD59 glycoprotein", "aln": "MGIQGGSVLFGLLLVLAVFCHSGHSLQCYNCPNPTADCKTAVNCSSDFDACLITKAGLQVYNKCWKFEHCNFNDVTTRLR-ENELTYYCCKKDLCN--FN--EQLENGGTSLSEKTVLLLVTPFLAAAWSLHP", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "E7F2M5-1", "uniprot_id": "E7F2M5_DANRE", "id": "E7F2M5-1", "name": "MAC-inhibitory protein", "aln": "MKASVG---VCVVFVLALLG-LGSAIKCYNCKDYTGACSKIKDCYYDDACLSVYERGGDTYRQCIKYSECDYSTVGVKFPKLSSFKFSCCTSDLCN----------SAPLSVSSRSVVAILLPLALFWWGVF-", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* * . :::: *:: . :::**** : .. *. * : . * :.*.:* : ..*: . : :: . ** **** .. * ::.: . ", "identical_positions": 20, "similar_positions": 37, "identity": "15.04%" }, { "cls_id": "homologset.agr.MGI:1888998", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D4AEI6-1", "uniprot_id": "D4AEI6_RAT", "id": "D4AEI6-1", "name": "Ubiquitin carboxyl-terminal hydrolase", "aln": "MAHLKIHGLVQIRSTNRSKHTRASQWKEAVIEIVERKQKVNLVVSFKLEERRRVFQLGDNVTGVVVSG-ELGLYHLDLTLRDDTSLLIDKLSSADVEHLKSFLDSSTPCESQQPMESMSNQDTLEISDPFFRENQDVVCVSLNTALESGTLLSRKMPLCMSNTTGSHTEKKRGEKQGRKRKTEPSPSTVEVTTKDILKENNPEQKKKSRRYYSRNRGGKAEKAVALREQEKRNNWKLEPAFSSKVYGKSTLDGTVLPIATCSDDRDLSIFGLEIITHNG------IQPPPDNYLKQLKREGFPNLGNTCYMNSILQSVFGIPTFAKDLLTQGIPWEKVSYDDLIMPLSQLLVLKDIRDIEIKGELLTSVKKSISTVADTFSGNEQNDAHEFLSLCLDQLKLNMEKVNAMWDTERKN--------EPT-CAGAKRFVCPVGANFEFELHSSIICEGCGEATLKTEVSNYLSIDLHHGTKTHPLSIQKSFDLFFTPEKIEHNCEKCKNKNSVLKYTLRRLPRVLIVHLKRYQVTTDLLPVKSEQPVEISQYLNISSHCHENRKLPFPLINTPPKGDYDIPNVSPGLMPEIFSQSMSSKKVISESSDPLVLQVGSSVDAEIQSFQIMYEDE--SEEEQQRGLESGSMLDPELLKTENRVFRQKISPAPDSMMGDGYSFLPMLCEP----MSIQDPGLAEMGLQEVPENPEFK------YYGKPDGRTNSELS--------------------KLHQNHGGRIKGSYLPAS---FANMRSSLEDPEKDLSRSSEF---EEDDPHSFALGSDE-------------------SKDEEMGDNLHNYRLVSVVSHFGSSPNSGHYVSDVYDFQRQAWLLYSDVQVFENPDPSSQENRLHTGYIFFYMHNEIFEELLKKASECKVLSTSKEEKRDIDYFSTLLNGLTYILEEF", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9ES63-1", "uniprot_id": "UBP29_MOUSE", "id": "Q9ES63-1", "name": "Ubiquitin carboxyl-terminal hydrolase 29", "aln": "MAHLKINGLVQIRSTNRSKHTRASQWKEAVIEIVERKQKVNLVVSFKLEERRRVFQLGDNVTGVVVSG-ELGLYHLDLTLRDDTSLLIDKLSSADVEHLKSFLDSSTPCESQQPMEPMSSQDDLESSDPFCGEHQEAACGSLNTTPESGTPLSRKMPLSMSNTTGGQ---KRGEKQGRKRKTEPSSSSAEVN-KDIPKENTPDQKKKSRRYYSRNRGGKAEKAVTLREQEKRSNWKLEPAFNSKSYGRANLDGTILPIATCSDDRDVSIFGLEIITHNG------VQSLPDPYLNQLKREGFPNLGNTCYMNSILQSVFGIPTFAKDLLTQGIPWEKVSYDDLIMPLSQLLVLKDIRDVEIKGELLTSVKKSISTVADTFSGNEQNDAHEFLSLCLDQLKLNMEKVNAMWDTERRN--------TCAGSAGTKRFVCPVGANFEFELHSSIICEGCGEATIKTEVSNYLSIDLHHGTKTHPLSIQKSFDLFFTPEKIEHNCEKCKNKNSVLKYTLRRLPRVLIVHLKRYQVTTDLLPVKSEQPVEISKYLNISSHCHENRKLPFPLANTSP-------DVSQGMMPGIFNQSMLSKKVISESCDPMVLQVGSSVDAEIQSFQIMYEDEDASEEQQQRGLESGSMLEPELVKTENRILRQKTSLATDSMMGDGYSFLPMLCEP----LSIQDPGLAEMGLQEVPENPEFKNYEKINIYGKSDGRTNTELS--------------------KLYQNHGSRIKGLFLPAS---LASV-SSQEDPEKDLSRSPEL---QEDDPHSFAFGSDD-------------------SKDGEMGDDLQNYRLVSVVSHFGSSPNSGHYVSDVYDFQKQAWLLYSDVQVFESSDPSIQENRLNSGYIFFYMHNEIFEELLKKASECKVLSTSKEEKRDIDYFSTLLNGLTYILEEF", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9HBJ7-1", "uniprot_id": "UBP29_HUMAN", "id": "Q9HBJ7-1", "name": "Ubiquitin carboxyl-terminal hydrolase 29", "aln": "MISLKVCGFIQIWS----QKTGMTKLKEALIETVQRQKEIKLVVTFKSGKFIRIFQLSNNIRSVVLRHCKKRQSHLRLTLKNNVFLFIDKLSYRDAKQLNMFLDIIHQNKSQQPMKSDDDWSVFESRN-MLKEIDKTSFYSICNKPS-----YQKMPLFMSKSPTHV---KKGILENQGGKGQNTLSSDVQTNEDILKEDNPVPNKKYKTDSLKYIQSNRKNPSSLEDLEKDRDLKLGPSFNTNCNGNPNLDETVLATQTLNAKNGLTSP-LEPEHSQGDPRCNKAQVPLDSHSQQLQ-QGFPNLGNTCYMNAVLQSLFAIPSFADDLLTQGVPWEYIPFEALIMTLTQLLALKDFCSTKIKRELLGNVKKVISAVAEIFSGNMQNDAHEFLGQCLDQLKEDMEKLNATLNTGKECGDENSSPQMHVGSAATKVFVCPVVANFEFELQLSLICKACGHAVLKVEPNNYLSINLHQETKPLPLSIQNSLDLFFKEEELEYNCQMCKQKSCVARHTFSRLSRVLIIHLKRYSFNNAWLLVKNNEQVYIPKSLSLSSYCNESTKPPLPLSSSAPVGKCEVLEVSQEMISEINSPLTPSMKLTSESSDSLVLPVEPDKNADLQRFQRDCGDA--SQEQHQRDLENGSALESELVHFRDRAIGEKELPVADSLMDQGDISLPVMYEDGGKLISSPDTRLVEVHLQEVPQHPELQKYEKTNTFVEFNFDSVTESTNGFYDCKENRIPEGSQGMAEQLQQCIEESIIDEFLQQAPPPGVRKLDAQEHTEETLNQSTELRLQKADLNHLGALGSDNPGNKNILDAENTRGEAKELTRNVKMGDPLQAYRLISVVSHIGSSPNSGHYISDVYDFQKQAWFTYNDLCVSEISETKMQEARLHSGYIFFYMHNGIFEELLRKAENSRLPSTQAGVIPQGEYEGDSLYRPA------", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* **: *::** * ::* :: ***:** *:*:::::***:** : *:***.:*: .**: : ** ***:::. *:***** *.::*: *** :*****:. .. . :* : : * :.. *: . . :**** **::. *:* :.: * : : *: . :** **:.* :** : : .: ::. :*.: ** : ** *:*.:: *...** *:*. * . ...:: ** :* * * : :**: :************::***:*.**:**.******:*** :.:: ***.*:***.***: . :** *** .*** **:**: **** ********. ****** :***:** :* :. . .*.:* ***** *******: *:**:.**.*.:*.* .*****:**: **. *****:*:****. *::*:**: **:*..* ::*: **.****:*****.... * **.:: * *.: *.:**:*:*. * *:** .:.* :** ::. * . * *: ***.*.:** * .. :*::* ** * *:*::**.**.** *:.**:: .:* : :* ..**:*.:* **:: * :* *. *.*: *****::**:: : : : : :* : :* * * . :* : . .: *..*: *.:*.*: : * * *:***: ::: :*** *: ***:*****:*********:*******:***: *.*: * * .:.. ** **::********* ******:**.:.:: **. : :* . * : ", "identical_positions": 363, "similar_positions": 263, "identity": "38.41%" }, { "cls_id": "homologset.agr.MGI:1888999", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q6TMA8-1", "uniprot_id": "ANGL4_RAT", "id": "Q6TMA8-1", "name": "Angiopoietin-related protein 4", "aln": "MRCAPTAGAALVLCAATAGLLSAQGRPAQP---EPPRFASWDEMNLLAHGLLQLGHGLREHVERTRGQLGALERRMAAC-------GNACQGPKG-----TDPKDRVPEG-------------QAPETLQS------------------------------------LQTQLKAQNSKIQQLFQKVAQQQRYLSKQNLRIQNLQSQIDLLTPTHLDNGVDKTSRGKRLPKMAQLIGLTPNATRLHRPPRDCQELFQEGERHSGLFQIQPLGSPPFLVNCEMTSDGGWTVIQRRLNGSVDFNQSWEAYKDGFGDPQGEFWLGLEKMHSITGDRGSQLAVQLQDWDGNAKLLQFPIHLGGEDTAYSLQLTEPTANELGATNVSPNGLSLPFSTWDQDHDLRGDLNCAKSLSGGWWFGTCSHSNLNGQYFHS-IPRQRQQRKKGIFWKTWKGRYYPLQATTLLIQPMEATAAS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9Z1P8-1", "uniprot_id": "ANGL4_MOUSE", "id": "Q9Z1P8-1", "name": "Angiopoietin-related protein 4", "aln": "MRCAPTAGAALVLCAATAGLLSAQGRPAQP---EPPRFASWDEMNLLAHGLLQLGHGLREHVERTRGQLGALERRMAAC-------GNACQGPKGKDAPFKDSEDRVPEG-------------QTPETLQS------------------------------------LQTQLKAQNSKIQQLFQKVAQQQRYLSKQNLRIQNLQSQIDLLAPTHLDNGVDKTSRGKRLPKMTQLIGLTPNATHLHRPPRDCQELFQEGERHSGLFQIQPLGSPPFLVNCEMTSDGGWTVIQRRLNGSVDFNQSWEAYKDGFGDPQGEFWLGLEKMHSITGNRGSQLAVQLQDWDGNAKLLQFPIHLGGEDTAYSLQLTEPTANELGATNVSPNGLSLPFSTWDQDHDLRGDLNCAKSLSGGWWFGTCSHSNLNGQYFHS-IPRQRQERKKGIFWKTWKGRYYPLQATTLLIQPMEATAAS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9BY76-1", "uniprot_id": "ANGL4_HUMAN", "id": "Q9BY76-1", "name": "Angiopoietin-related protein 4", "aln": "MSGAPTAGAALMLCAATAVLLSAQGGPVQS---KSPRFASWDEMNVLAHGLLQLGQGLREHAERTRSQLSALERRLSAC-------GSACQGTEG-----STDLPLAPESR------------VDPEVLHS------------------------------------LQTQLKAQNSRIQQLFHKVAQQQRHLEKQHLRIQHLQSQFGLLDHKHLDHEVAKPARRKRLPEMAQPVDPAHNVSRLHRLPRDCQELFQVGERQSGLFEIQPQGSPPFLVNCKMTSDGGWTVIQRRHDGSVDFNRPWEAYKAGFGDPHGEFWLGLEKVHSITGDRNSRLAVQLRDWDGNAELLQFSVHLGGEDTAYSLQLTAPVAGQLGATTVPPSGLSVPFSTWDQDHDLRRDKNCAKSLSGGWWFGTCSHSNLNGQYFRS-IPQQRQKLKKGIFWKTWRGRYYPLQATTMLIQPMAAEAAS", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1NYZ0-1", "uniprot_id": "A0A8M1NYZ0_DANRE", "id": "A0A8M1NYZ0-1", "name": "", "aln": "MKVPLANLLCITVLASSGTSFPMERRGAAAGKEKRVQYAAWDDVNVLAHGMLQLGQGLKEHVDKTKGQVRDITIKMKVFNVTVSELGKLTQQLQEDNELLKAKAQNLEDSESLVLNVSTDLRQKTDELLKDRQKDHERMNKLEEKVDGLMQGEGLEAANSNYSDARIIQWMLEAQNKRIDDLVERIKQQQEKLDKQNIRIRTLQNQITMKN---------ERLSLKRMEEDVNLNASTEQRDSPVALASDCHELFLRGETSSGLYTIQPSDSQPFEVYCEMTPEGGWTVIQRRQDGSVDFDQLWQAYQNGFGNLNGEFWLGLEKIHSVSKGGNYILKVQFSDWRDEIQSISYRFHLNGQENNYSLRILESPAGNT-ESSLPTETSAVPFSTRDKDNDQKNDLNCAKQLSGGWWFSNCGRSNLNGRYFVTPAPKQRHQRKQGVFWKTWRGRYYPLKTTTMMIAPAEIVNKS", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* . : .: : *::. :. : . . : ::*:**::*:****:****:**:**.::*:.*: : :: . *. * : . :. * *:. :* *:***.:*::*..:: ***. *.**::**: **.*: : : **: : .: : : . **:*** ** ***: *** .* ** * *:**.:********* :*****:: *:**: ***: :*********:**:: . . * **: ** .: : :.: .**.*::. ***:: . *.: :.:... ::**** *:*:* : * ****.*******..*.:*****:** : *:**:: *:*:*****:******::**::* * *", "identical_positions": 155, "similar_positions": 129, "identity": "32.98%" }, { "cls_id": "homologset.agr.MGI:1889000", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9QXE2-1", "uniprot_id": "DPOLL_MOUSE", "id": "Q9QXE2-1", "name": "DNA polymerase lambda", "aln": "MDPQGIVKAFPKRKKSHADLSSKALAKIPKREVG-EARGWLSSLRAHIMPAGIGRARAELFEKQIIHHGGQVCSAQAPGVTHIVVDEDMDYERALRLLRLPQLPPGAQLVKSTWLSLCLQEGRLTDTEGFSLPMPKRSLDEPQPSKSGQDASAP-GTQRDLPRTTLSLSPPHTRAVSPPPTAEKPSRTQAQLSSEDETSDGEGPQVSSADLQALITGHYPTPPEEDGGPDPAPEALDKWVCAQPSSQKATNYNLHITEKLEVLAKAYSVQGDKWRALGYAKAINALKSFHKPVSSYQEACS-IPGIGKRMAEKVMEILESGHLRKLDHISDSVPVLELFSNIWGAGTKTAQMWYHQGFRNLEDLQSLGS----LTAQQAIGLKHYDDFLDRMPREEAAEIEQTVRISAQAFNPGLLCVACGSYRRGKMTCGDVDVLITHP---DGRSHRGIFSCLLDSLRQQGFLT-----------------------------------------------------------------DDLVSQEENGQQQKYLGVCRLPGP----GKRHRRLDIIVVPYCEFACALLYFTGSAHFNRSMRALAKTKGMSLSEHALSAAVVRNSQGVKVGPGQVLPTPTEKDVFKHLGLPYREPAER--DW-----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q5RKI3-1", "uniprot_id": "DPOLL_RAT", "id": "Q5RKI3-1", "name": "DNA polymerase lambda", "aln": "MDPQGILKAFPKRKKIHADPSSNALAKIPKREAG-DARGWLSSLRAHIMPTGIGRARAELFEKQIIQHGGQVCSAQAPGVTHIVVDEGMDYERALRLLRLPQLPPGAQLVKSAWLSLCLQEKKLTDTDGFSLSSPKRSLNEPQPSKSGQDASAP-GTQGVLPRTTLSLSPPCTRAVSPPPKAEKPPKTQTQLSSEDEASDGEGPQVSSADLQALISGHYPTPPGEDGGPDPAPEALGKWVCAQPSSQKATNYNLHITEKLEVLAKAYNVQGDKWRALGYAKAINALKSFHKPVSSYQEACS-IPGVGRRMAEKVMEILESGHLRKLDHISDSVPVLELFSNIWGAGTKTAQMWYHQGFRSLEDIRGLAS----LTAQQAIGLKHYDDFLDRMPREEAAEIEQMVRVSAQAFNPGLLCVACGSFRRGKVTCGDVDVLITHP---DGRSHQGIFSPLLDSLRQQGFLT-----------------------------------------------------------------DDLVSQEENGQQQKYLGVCRLPGA----GQRHRRLDIIVVPYSEFACALLYFTGSAHFNRSMRALAKTKGMSLSEHALSAAVVRNSQGVKVGAGQVLPTPTEKDVFKLLGLPYREPAER--DW-----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9UGP5-1", "uniprot_id": "DPOLL_HUMAN", "id": "Q9UGP5-1", "name": "DNA polymerase lambda", "aln": "MDPRGILKAFPKRQKIHADASSKVLAKIPRREEGEEAEEWLSSLRAHVVRTGIGRARAELFEKQIVQHGGQLCPAQGPGVTHIVVDEGMDYERALRLLRLPQLPPGAQLVKSAWLSLCLQERRLVDVAGFSIFIPSRYLDHPQPSKAEQDASIPPGTHEALLQTALSPPPPPTRPVSPPQKAKEAPNTQAQPISDDEASDGEETQVSAADLEALISGHYPTSLEGDCEPSPAPAVLDKWVCAQPSSQKATNHNLHITEKLEVLAKAYSVQGDKWRALGYAKAINALKSFHKPVTSYQEACS-IPGIGKRMAEKIIEILESGHLRKLDHISESVPVLELFSNIWGAGTKTAQMWYQQGFRSLEDIRSQAS----LTTQQAIGLKHYSDFLERMPREEATEIEQTVQKAAQAFNSGLLCVACGSYRRGKATCGDVDVLITHP---DGRSHRGIFSRLLDSLRQEGFLT-----------------------------------------------------------------DDLVSQEENGQQQKYLGVCRLPGP----GRRHRRLDIIVVPYSEFACALLYFTGSAHFNRSMRALAKTKGMSLSEHALSTAVVRNTHGCKVGPGRVLPTPTEKDVFRLLGLPYREPAER--DW-----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P25615-1", "uniprot_id": "DPO4_YEAST", "id": "P25615-1", "name": "DNA polymerase IV", "aln": "MSLKGKFFAFLP----NPNTSSNKFFKSILEKKG-----------ATIVSSIQNCLQSSRKEVVILIEDSFVDSDMHLTQKDIFQREAGLNDVDEFLGKIEQS--GIQCVKTSCITKWVQNDKFAFQKDDLIKFQPSIIVISDNADDGQ-----------------------------SSTDKESEISTDVESERNDDSNNKDMIQASKPLKRLLQG-------------------DKGRASLVTDKTKYKNNELIIGALKRLTKKYEIEGEKFRARSYRLAKQSMENCDFNVRSGEEAHTKLRNIGPSIAKKIQVILDTGVLPGLNDSVGLEDKLKYFKNCYGIGSEIAKRWNLLNFESFCVAAKKDPEEFVSDWTILFGWSYYDDWLCKMSRNECFTHLKKVQKALRGIDPECQVELQGSYNRGYSKCGDIDLLFFKPFCNDTTELAKIMETLCIKLYKDGYIHCFLQLTPNLEKLFLKRIVERFRTAKIVGYGERKRWYSSEIIKKFFMGVKLSPRELEELKEMKNDEGTLLIEEEEEEETKLKPIDQYMSLNAKDGNYCRRLDFFCCKWDELGAGRIHYTGSKEYNRWIRILAAQKGFKLTQHGL----FRNN--------ILLESFNERRIFELLNLKYAEPEHRNIEWEKKTA", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*. :* . ** :.: **: : * .: * * :: : . ::. * *: ... : . ..*. * : * :: * * * **:: :: :*: ::. . : : .: :. * . . ::. : . :: *:.: :: *: *: * .* .: :.:. : * * *: *:* *.::*:*:** .* * ::::. . * * :** : : .:* :*:*: **::* * *:. *: *.* :* *:: *: * .*..: . :* .:*.*:* :*.*:*. : *: : :.::. **:.** .***:*:*: :* * . *:. * .* ::*:: . *: :**: :: * : : . *. ****:: : *:... :::*** .:** :* ** **:.*::*.* .**. :* : .*: :*. *.* * ** .* :* ", "identical_positions": 116, "similar_positions": 177, "identity": "17.6%" }, { "cls_id": "homologset.agr.MGI:1889001", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I5ZLQ1-1", "uniprot_id": "A0A8I5ZLQ1_RAT", "id": "A0A8I5ZLQ1-1", "name": "", "aln": "MAQKKYLQAKLTQFLREDRIQLWKPPYTEENKEVG-LALKDLAKRYSERLECCENEVENIIEEIRCKAIERGTGNEHYRTTGIATIEVFLP-PRLR---KVSSFKTAMLCSSEEQ--LIAETFGFQENYIKIVIN-KKQLQLGKSLEEQGVTHNVKAMVLELKQSEEDVRRNLQLEEEEQNEAEQKEKRIQRTKRGLEILAER-AEMVVDPETMPYLDIANQTGRSIRIPPSERKALMLAMGYHEKGRAFLKRKEYGIALPCLLDADRYFCEC-KELLDTVDNYAVLQLDIVWCYFRLEQLECLDDAEKKLNLAQTCFTNCYGENHQRLVNIKGNCGKEKVLFLRLYLLQGIRNYHSGNGEEAREYLNKARQLFKELYIDPSKVHNLLQLGFTAQEARLGLRACDG--NVDHAATHISNRREELAQIRKEEKEKRKRR----------------LESVNTLRGMGYSTQAAKQALHQARGNLDDALKILLSNPHMWWLQDSDSENNSRQASPSQESIDQLVYMGFDTVVAEAALRVFAGNVQLAAQTLAHHGGSLPPDLQFSGEDSSSTPSTSPSDSAGTSSAST-----------------------DEDMETEAVNEILEDIPEHEEDYLDSTLEDEEVIIAEYLSYVDRTSSATKDN", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P54729-1", "uniprot_id": "NUB1_MOUSE", "id": "P54729-1", "name": "NEDD8 ultimate buster 1", "aln": "MAQKKYLQAKLTQFLREDRIQLWKPPYTKENKEVG-LAVKDLAKKYSERLECCENEVENIIEEIRRKAIERGTGNEHYRTTGIATIEVFLP-PRLRKHDKKSLLETRLHVTGRDLRCQIAETFGFQENYIKIVIN-KKQLQLGKSLEEQGVTHNVKAMVLELKQSEEDVRKNLQLEEEEQNEAELKERRIQRTKRGLEILAER-AEMVVDPETMPYLDIANQTGRSLRIPPAERKALMLAMGYHEKGRAFLKRKEYGIALPCLLDADRYFCEC-KELLDTVDNYAVLQLDIVWCYFRLEQLECLDDAEKKLNLAQKCFKNCYGENHQRLVHIKGNCGKEKVLFLRLYLLQGIQNYHSGNGEEAREYLNKARQLFKELYIDPSKVHNLLQLGFTAQEARLGLRACDG--NVDHAATHISNRREELAQIRKEEKEKRRRR----------------LENVNTLRGMGYSTQAAKQALHQARGNLDDALKVLLSNPHMWWLQDADPENNSRQASPSQESINQLVYMGFDTVVAEAALRVFGGNVQLAAQTLAHHGGSLPPDLQFSGEDSSPTPSTSPSDSAGTSSAST-----------------------DEDMETEAVNEILEDIPEHEEDYLDSTLEDEEVIIAEYLSYVESISSAAKNN", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9Y5A7-1", "uniprot_id": "NUB1_HUMAN", "id": "Q9Y5A7-1", "name": "NEDD8 ultimate buster 1", "aln": "MAQKKYLQAKLTQFLREDRIQLWKPPYTDENKKVG-LALKDLAKQYSDRLECCENEVEKVIEEIRCKAIERGTGNDNYRTTGIATIEVFLP-PRLKK-DRKNLLETRLHITGRELRSKIAETFGLQENYIKIVIN-KKQLQLGKTLEEQGVAHNVKAMVLELKQSEEDARKNFQLEEEEQNEAKLKEKQIQRTKRGLEILAKRAAETVVDPEMTPYLDIANQTGRSIRIPPSERKALMLAMGYHEKGRAFLKRKEYGIALPCLLDADKYFCECCRELLDTVDNYAVLQLDIVWCYFRLEQLECLDDAEKKLNLAQKCFKNCYGENHQRLVHIKGNCGKEKVLFLRLYLLQGIRNYHSGNDVEAYEYLNKARQLFKELYIDPSKVDNLLQLGFTAQEARLGLRACDG--NVDHAATHITNRREELAQIRKEEKEKKRRR----------------LENIRFLKGMGYSTHAAQQVLHAASGNLDEALKILLSNPQMWWLNDSNPETDNRQESPSQENIDRLVYMGFDALVAEAALRVFRGNVQLAAQTLAHNGGSLPPELPLSPEDSLSPPATSPSDSAGTSSAST-----------------------DEDMETEAVNEILEDIPEHEEDYLDSTLEDEEIIIAEYLSYVENRKSATKKN", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M3AW93-1", "uniprot_id": "A0A8M3AW93_DANRE", "id": "A0A8M3AW93-1", "name": "", "aln": "MMEEQHLQARLIALLRQDKIQLWLEPYRSLRDPADRLKIQELAEKYASVIQFPVEEVTSALESIRTDTSRKDEGNKEFKETAVATLVLHLPREEGETKIKKVELKTKLDITTQELKKQISQEFGFTH---FNLIC-GKVLSPERRLDEQKVKNNSKIMVVKG--APPDAKAEMYKNEEEK---RKQDEEIKKTQKGFQILSER--DGSEDPSTTPFLEIADQKGNPLQIPDEERKALILAMGFHEKGRALMKKRDHSAALPYLVLADEQFKKCNSAILHTVDNYAVLQLDVVWCYQALGQLECLDNARQRLEKAEQCFQKCYGEKQSRLQQIKGHTGGEEVLFLRLRILQTLLTYIEGHKNQALGKLKDVEHLYGELSLDPQKLQQLKELGFSEQEARLGLRACRG--DVSEAALLITQRKKEKQVLKLKEQDKRRRR----------------LQDINTLVELGFERRDAQRALHQARGDVDKAYGILLDG--------ADAQKSDRD-----KKLNELLSMGFQEDMADSALRMTGDDVQQATQLLLENQAVIPADLQSPSPPSSSSEEPSTS-SESTGSSRQ-----------------------DEDLL---VNELLEDIPKHEEDYLDLTLEEEKELMDKIRTILEK--------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VRF3-1", "uniprot_id": "Q9VRF3_DROME", "id": "Q9VRF3-1", "name": "UBA domain-containing protein", "aln": "MSQNDNLLIQIRALLQSDGEKLWEEPYYSEDLGSIEGALENLAQKYSGMLGIDIGRCKFFLTELQENALRTLAARREFSTTGIATLKVRRVGEHSG--ATMVEVKCSLDIVGSELQACIAKKLEVPNAAHVKCIAAGKVVSANATLADQQLKNNQQLIVIVGDGDNSGE---------------ALYERINRIKADVEAVVSS---------KNNLIEMEDQNGSQVYLPPSEHKALLMGLGFCEKARAAMNRKHFEEALLLLLEADEHFSTCGSKFLESVDNYALLNLDIVWCYFCLKNVTQLPDAEHRLARCSRNFGISYGDNLERLYSLKGKDCPERALIMRLKLLQGVIFFHQNLRNQAFECFEAAKTLLNELKINNDQLALLVDMGFEPSEARMALRSCKGGTAVEQAVQFIHERRQQLKNARMKYKASERAMERRLKRSNSKDCTWVNPRSVCSLADMGFESGLATIALQRSNNDILQAVELLQTES-----DELTGASPWFPVTVDTTKLAQLLQLGFNENDSRVALQNASNNMEEAIESLMCAIESEEELKAILKHVGRLAENGGQNLDGPSTSNASGQTQVALPAP---IIEAVINHARVEIETYKAYERFNSDLKLSDLEYLDLPLIQEEKILTEYFNMLQQ--------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VBQ3-1", "uniprot_id": "Q9VBQ3_DROME", "id": "Q9VBQ3-1", "name": "UBA domain-containing protein", "aln": "MSQINNIFIKLRARLRERDIKLWEEPYYFEEVGSIESEMDRLARDISGELGISVSDCRIALGELQDGALRKLAARREFNDTGLATFNVRCVDSKGGT-VQMLEIKCSLGGLGSDLQAEVAKKLDIVDSSHVKCISGGRIINGQKTLASQGLKTNQHLMVVVG-GTNEGQ---------------ELHERIQRIRADLELVADA---------DR-FMEMEDQDGRPIFLPREENRSLLMAMSMYEVARVAMHKENFDEALLILLEADELFSQCDSKLLEGVDNYALINLDIVWCYLRLKNITQLPDAQRRLDICERGFVKSYGEQFIRLFSIKGPSSPERALIMRLHLLQGVLLFHQNRRDEAYEKLEVATKDLYEVKMNDTELSTLVEMGYEESDARLALRSCAG--QVDRAIQYIQERSERISEER-KNSAAERQVNQEMIFAG-QGGEWVNPRSIIRLMEMGYERRLVVEALKRTKNNLDRSLDLLQRHS-----DELRANLPPIPP-VDESLLTTLQHLGFSEISARDALETTGNSFHKSLKFLLKSFPNESELLHVIETMTKVLEVQEPTSSTNATANST-TPLVNLSNSKVNLLQTVLSEAKSEIESYNAFKRFNENLAENNNHYLNLPLDQEEQILIEYKRLLEG--------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* : . : :: *:. :** ** :. **. : : : .:: : . .. .: *.:**: : . .: : : ::: : . . * : :. * .* : * : :*: . ..*:: : ..: : . ::: :* * : :* *.::*::.:. * .*. :::... ** *: **. * * :*. *****:::**:**** * :: * :*.::* .. * .**:: ** :** *..*::** :** : : .. :* :: . *: :: :: * ::*: .:**:.**:* * *..* * :* :. : : . .: ..: * :*:. . .*: : .:: : :* : * :**. : **. .... : : * . . : : * :.: .:: : .**: .* :*: :: : :: ", "identical_positions": 89, "similar_positions": 182, "identity": "13.48%" }, { "cls_id": "homologset.agr.MGI:1889002", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D4A0Q3-1", "uniprot_id": "D4A0Q3_RAT", "id": "D4A0Q3-1", "name": "", "aln": "MRPLPVRMLLPRTPFARCRVTSLAGATRKGAERRTCAEAADGPMASSAGLALCAQTLVVRGGSRFLAFSTASSDDDCLFSYDCSTAEKKS---VQEDKGEDGQPADRGSDTILAST--FSKSGRYFALTDDSKR--LILFRTKP--WQCLSVR---TVVRRCTALTFTASEDRVLVADKSGDVYSFPVLDSGG---CGRLELGHLSMLLDVAVSPD---DQFVLTADRDEKIRVSWAAAPHSIEAFCLGHTEFVSRIFVVPSHPELLLSSSGDGTLRLWKYRSGCQLQCCDLASLQE-------------PGEHSVHKGLAASRIAFWGRESYVVLLCECVPVGFVFQLDASRQ---QLVFRQRLTFPHRVWDVVFEETRGLWVLQDCRDAPLALWRPMGSEWQAAP-DDAVSQRLCSHLRESWAMLEGS-AGADDGFRSLYKATFDNMTSYLKKKEERLKQQLKKK-RQRSPHPGSPEQTKKACPARAVSP--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9EP82-1", "uniprot_id": "WDR4_MOUSE", "id": "Q9EP82-1", "name": "tRNA (guanine-N(7)-)-methyltransferase non-catalytic subunit WDR4", "aln": "-------------------------------------------MASSAGLALCAQTLVVRGGSRFLAFSTTGSDDDCVFTYDCSTAEKKA---TPEDKGEDGQPADTGSDSILAST--FSKSGRYFALTDDSKR--LILFRTKP--WQCLSVR---MVVRRCTALTFTASEDRVLVADKSGDVYSFSVLEPDG---CGRLELGHLSMLLDVAVSPD---DQFVLTADRDEKIRVSWAAAPHSIESFCLGHTEFVSRILVVPSHPELLLSSSGDGTLRLWEYRSGRQLQCCDLAGLQE-------------PGEQPGHKGLAASRIAFWGQESYVVLLCECVPVVFVFQLDASRQ---QLVFRQRLTFPHRVWDVVFEEARGLWVLQDCRDAPLVLWRPVGGEWQAAP-DGAVSPRLCSHLRESWAMLEGS-VGTDDSFRSLYKATFDNMTSYLKKKEERLQQQLKKK-RQRSPFPGSPEQTKKACPGQSALSC-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P57081-1", "uniprot_id": "WDR4_HUMAN", "id": "P57081-1", "name": "tRNA (guanine-N(7)-)-methyltransferase non-catalytic subunit WDR4", "aln": "-------------------------------------------MAGSVGLALCGQTLVVRGGSRFLATSIASSDDDSLFIYDCSAAEKK----SQENKGED-APLDQGSGAILAST--FSKSGSYFALTDDSKR--LILFRTKP--WQCLSVR---TVARRCTALTFIASEEKVLVADKSGDVYSFSVLEPHG---CGRLELGHLSMLLDVAVSPD---DRFILTADRDEKIRVSWAAAPHSIESFCLGHTEFVSRISVVPTQPGLLLSSSGDGTLRLWEYRSGRQLHCCHLASLQE-------------LVDPQAPQKFAASRIAFWCQENCVALLCDGTPVVYIFQLDARRQ---QLVYRQQLAFQHQVWDVAFEETQGLWVLQDCQEAPLVLYRPVGDQWQSVP-ESTVLKKVSGVLRGNWAMLEGS-AGADASFSSLYKATFDNVTSYLKKKEERLQQQLEKKQRRRSPPPGPDGHAKKMRPGEATLSC-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A4IGH4-1", "uniprot_id": "WDR4_DANRE", "id": "A4IGH4-1", "name": "tRNA (guanine-N(7)-)-methyltransferase non-catalytic subunit wdr4", "aln": "----------------------------------------------MAVVCSKADWFVTSCSTTLVAVNLKQSREP--FVFDCSKAEKKPKEADVDNKSAGEGSEEKDSDSILAFA--ISASGKHVALTDDHKR--LVLFCTEPS-WKCISTR---WVVRRCTSLAFTQAEDELYVADKSGDVYSFSILEPHK---AGELKLGHLSMLLDVALSPD---DKYIITADRDEKIRVSFRRSPYNIQAFCLGHTEFVSSLLVPAGHPDWLLSGSGDGTVNVWHYETGRRLHSVDMRKFG--------------LDSENTEKRFAVSRIISSPDGQHVAVQCEGFPSVQLFTVDCGTEG--LLKPADTLTLPLSPWDVTFDSENQLWVLLESEDMKVLLYRHSEQHWRLCDSESPELKKVTNALQTQWHLFKGS-VGLESQFKHLYKVNFDNMASYLQKKQERLDLEHKKR--AAAANGSKPNKKSKTESGAVPQSTS", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9W415-1", "uniprot_id": "WUHO_DROME", "id": "Q9W415-1", "name": "tRNA (guanine-N(7)-)-methyltransferase non-catalytic subunit wuho", "aln": "--------MCTTISFAEPEIVLGHGRRVLFVNPDDLQIFKEIELPPDLGLKGHTSQSQESCTAAAAASTATAASGQAPGGKEQQLANQPE---EGGTSASASGLGCATSTSVQNVA--YSPDGQLLAVTTSGKQKALLLYRSRPENARLLSAR---PLARASSALRFCSDSSSILVTDKTGDCYQYDCVEVEA---PPRLLLGHLSVVYDILWSED---QQHIITCDRDDKIRVTNYPATFDIHSYCLGHREFVSGLALLT--EQHIASASGDKTLRVWNYIQGKELLQHEL---------------------PAPAVRLLVRQLEPEKVFQAAVLFYEHVDALGLYRLERSSDDTWSVTATQLVCAEAGSWSISNFTLTSDRIYITGAENERLSLRVYDIATGQPASSGVPEGWLKMVLDGLGANEEGAPPFIPEDLSVWFKKRFDNVSDYLERKKRRIEEQQQQK------------------CG-------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q03774-1", "uniprot_id": "TRM82_YEAST", "id": "Q03774-1", "name": "tRNA (guanine-N(7)-)-methyltransferase non-catalytic subunit TRM82", "aln": "--------MSVIHPLQNLLTSRDGSLVFAIIKNCILSFKYQSPNHWEFAGKWSDDFDKIQESRNTTAKEQQGQSSENENENKKLKSNKGDSIKRTAAKVPSPGLGAPPIYSYIRNLRLTSDESRLIACADSDKS--LLVFDVDKTSKNVLKLRKRFCFSKRPNAISIAEDDTTVIIADKFGDVYSIDINSIPEEKFTQEPILGHVSMLTDVHLIKDSDGHQFIITSDRDEHIKISHYPQCFIVDKWLFGHKHFVS--SICCGKDYLLLSAGGDDKIFAWDWKTGKNLSTFDYNSLIKPYLNDQHLAPPRFQNENNDIIEFAVSKIIKSKNLPFVAFFVEATKCIIILEMSEKQKG--DLALKQIITFPYNVISLSAHN-DEFQVTLDNKES--------------SGVQKNFAKFIEYNLNENSFVVNNE---KSNEFDSAIIQSVQGDSNLVTKKEEIYPLYNVSS---------------LRKHGEHYS---", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . * . ::: . : * .. .* : . * *::: . :. * . : .:: : . : ::** ** *. . . ***:*:: *: * .:.::*.***::*::: . :. : :** .*** : : *..** .: *.: * .* . : . :: ... : : :. . : : : .: : : . : * :. : .:. :. : :*:. . . ", "identical_positions": 35, "similar_positions": 97, "identity": "7.09%" }, { "cls_id": "homologset.agr.MGI:1889005", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9D2W0-1", "uniprot_id": "FXYD4_MOUSE", "id": "Q9D2W0-1", "name": "FXYD domain-containing ion transport regulator 4", "aln": "MEEITCAFLLLLAGLPALEASDP-VDKDSPFYYDWESLQLGGLIFGGLLCIAGIAMALSGKCKCRRTHKPSS-LPGKATPLIIPGSANTC", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q63113-1", "uniprot_id": "FXYD4_RAT", "id": "Q63113-1", "name": "FXYD domain-containing ion transport regulator 4", "aln": "MEGITCAFLLVLAGLPVLEANGP-VDKGSPFYYDWESLQLGGMIFGGLLCIAGIAMALSGKCKCRRNHTPSS-LPEKVTPLITPGSAST-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P59646-1", "uniprot_id": "FXYD4_HUMAN", "id": "P59646-1", "name": "FXYD domain-containing ion transport regulator 4", "aln": "MERVTLA-LLLLAGLTALEANDPFANKDDPFYYDWKNLQLSGLICGGLLAIAGIAAVLSGKCKCKSSQKQHSPVPEKAIPLITPGSATTC", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "** :* * **:****..***..* .:*..******:.***.*:* ****.***** .*******: .:. * :* *. *** ****.* ", "identical_positions": 53, "similar_positions": 23, "identity": "58.89%" }, { "cls_id": "homologset.agr.MGI:1889006", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P59648-1", "uniprot_id": "FXYD7_MOUSE", "id": "P59648-1", "name": "FXYD domain-containing ion transport regulator 7", "aln": "MATPTQSPTNVPEETDPFFYDYATVQTVGMTLATIMFVLGIIIILSKKVKCRKADSRSESPTCKSCKSELPSSAPGGGGV", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P59649-1", "uniprot_id": "FXYD7_RAT", "id": "P59649-1", "name": "FXYD domain-containing ion transport regulator 7", "aln": "MATPTQSPTNVPEETDPFFYDYATVQTVGMTLATIMFVLGIIIIISKKVKCRKADSRSESPTCKSCKSELPSSAPGGGGV", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P58549-1", "uniprot_id": "FXYD7_HUMAN", "id": "P58549-1", "name": "FXYD domain-containing ion transport regulator 7", "aln": "MATPTQTPTKAPEEPDPFYYDYNTVQTVGMTLATILFLLGILIVISKKVKCRKADSRSESPTCKSCKSELPSSAPGGGGV", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "******:**:.***.***:*** ************:*:***:*::***********************************", "identical_positions": 69, "similar_positions": 10, "identity": "86.25%" }, { "cls_id": "homologset.agr.MGI:1889007", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P0C5X8-1", "uniprot_id": "TTYH1_RAT", "id": "P0C5X8-1", "name": "Protein tweety homolog 1", "aln": "----MGAPPGYRPSAWVHLLHQLPRADFQLRPVPSGFAPRDQEYQQ----------------ALLLVAALAGLGLGLSLIFIAVYLIRFCCCR------PPEPPGAKSPPPGGG-----------CVTWSCIAALLVGCAGIGIGFYGNSETSDGVSQLSSALQHANHTLSTIDDLVLETVERLGEAVRTELTTLEEVLSERVELVAATRGARRQAEAAAQHLQGLAFWQG----------------------------------------VSLSPVQVAEDVTFVEEYRWLAYVLLLLLVLLVCLFTLLGLAKQSKWLVVVMTAMSLLVLVLSWGSMGLEAATAVGLSDFCSNPDTYVLNLTQEETGISSDILNYYFLCNQAVSNPFQQRLTLSQRALASIHSQLQGLEREASPQFP--AAQKPLLSLEETLNVTERSFHQLVALLHCRSLHKDYGSALRGLCEDALEGLLFLMLFSLLSAGALATTLCSLPRAWALFPP-SDDYDDTDDD--DPFNPQESKR-------------FVQWQSSI---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9D3A9-1", "uniprot_id": "TTYH1_MOUSE", "id": "Q9D3A9-1", "name": "Protein tweety homolog 1", "aln": "----MGAPPGYRPSAWVHLLHQLPRADFQLRPVPSGFAPRDQEYQQ----------------ALLLVAALAGLGLGLSLIFIAVYLIRFCCCR------PPEPHGAKSPPPGGG-----------CVTWSCIAALLVGCAGIGIGFYGNSETSDGVSQLSSALLHANHTLSTIDDVVLETVERLGEAVKTELTTLEEVLSVRMELVAATRGARRQAEAAAQYLQGLAFWQG----------------------------------------VSLSPVQVAEDVTFVEEYRWLAYVLLLLLVLLVCLFTLLGLAKQSKWLVVVMTAMSLLVLVLSWGSMGLEAATAVGLSDFCSNPDTYVLNLTQEETGLSSDILSYYFLCNQAVSNPFQQRLTLSQRALASIHSQLQGLEREAIPQFS--AAQKPLLSLEETLNVTERSFHQLVALLHCRSLHKDYGSALRGLCEDALEGLLFLMLFSLLSAGALATTLCSLPRAWALFPP-SDDYDDTDDD--DPFNPQESKR-------------FVQWQSSI---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9H313-1", "uniprot_id": "TTYH1_HUMAN", "id": "Q9H313-1", "name": "Protein tweety homolog 1", "aln": "----MGAPPGYRPSAWVHLLHQLPRADFQLRPVPSVFAPQEQEYQQ----------------ALLLVAALAGLGLGLSLIFIAVYLIRFCCCR------PPEPPGSKIPSPGGG-----------CVTWSCIVALLAGCTGIGIGFYGNSETSDGVSQLSSALLHANHTLSTIDHLVLETVERLGEAVRTELTTLEEVLEPRTELVAAARGARRQAEAAAQQLQGLAFWQG----------------------------------------VPLSPLQVAENVSFVEEYRWLAYVLLLLLELLVCLFTLLGLAKQSKWLVIVMTVMSLLVLVLSWGSMGLEAATAVGLSDFCSNPDPYVLNLTQEETGLSSDILSYYLLCNRAVSNPFQQRLTLSQRALANIHSQLLGLEREAVPQFP--SAQKPLLSLEETLNVTEGNFHQLVALLHCRSLHKDYGAALRGLCEDALEGLLFLLLFSLLSAGALATALCSLPRAWALFPP-SDDYDDTDDD--DPFNPQESKR-------------FVQWQSSI---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M3AHW7-1", "uniprot_id": "A0A8M3AHW7_DANRE", "id": "A0A8M3AHW7-1", "name": "Protein tweety homolog", "aln": "-MAAIATVPNYTPSVWVRLCHAIPRLSLTMQMRDSVFTPDSWEYQQ----------------TLLVLSSFSAIALVLSLLVILCFLIHYCCCHRGESGRDAEEEEEDDDASGGHGYSGKKGRGICCVTWVSVAAVTLCCVAIGVGFYGNSEANDGMYQLTSSLLTANYTLASIDLLVSDTISGLQRSVSGPLTSMEDVFGGHKPALVPTRSCRRLSERVVSLLSNLTLGRGLIPIADGFYRTNGSESIVGALTPAPPSVAPTLSPSANSIPAPFSPGWAANTLMVNEDYRWLSYVLLLLVDLVVCFFILLGLAKQSRWLLILMTVLAWLSLFMSWGSLGLETPTVVALSDFCFDPNTFVLNSTHFNSGTSPEVLDYYLTCSRKMSSPFQQILTQSQRALSSIHSHLSSLERDALPRFP--KAERSLREVQQILNTTEGNFHQLVALLNCRGLNKDYVDSLKGLCYDGMEGLLYLSLYSFLSALAFTAILCSLPGAWRSFHSDSDDYEDSDSESEDPFTSHQARRQTATGSQRGALPPFYSYQGAAWTPPFSSAPP----------------------------LPTPNVSSNGNPGYENLPLSDRQSPPPSYSPSMLTGYGGSQSHSNPSHSRNLYSH------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9U6L4-1", "uniprot_id": "TTY1_DROME", "id": "Q9U6L4-1", "name": "Protein tweety", "aln": "MGDYHEFTDQYKVPVIAKLLHALPHYNITFHKINSTFRPNDEIYLE----------------SLGILGSVPAALLIVSLLGLLFYLMTRCCDR------KPRPAHSITS-----------------LKVALSIVTVMCCAAIGLGLYGNDDLHNGLLEVLTAGRKVDNLVTTIRNQTHILENTLTNRIRPQLVELADIFDQPVSNQTALSKLFVSLNIVQGNVTLATNAASDIR----------------------------------RPLMGISMTHFLTRGDQWELIRWPGTVATLALLLVLCAVLLVGVARHSRCALILFSVCGLLAVTGSWLMSGLYLSSSVAVGDLCISPADFLVSTAPRD--LPTNVLLHYTQCEPGHTNPFTQRLRESQNSLNNARSAMATVMKISLVLFKSSGLQPKLGAVNADLNSSERLLTQLTALVDCKAVHHNFLAAARGLCEGGLLGLVLMLIASFIAAILLTIMVWVDSHTWIYIRK-RNDYAQVDEPSYISHPAPQNHQQMMNAARTLPRNHNGHFSPPVISGSHTLQHPSKRQQHEMMAHAHIQQNMRAMGTHTLGRLPSHNHSPTHMTGPNNAAAVAAAANAAANMPPTTQAAQQQQQQQAQQQQQQAQQQLGGPQPIYCHHPHQHPHPHPHQHPHSHSAAAVAAAVQHQHAIYHQQQAQQYGTYTTAAHHAPHHLGPGQSQIYQQIPAHLAPQLAANGNPHSIYQPLVAVSQGSIYVSNMATMRRQNSQGGPQIPAHQHPPSLHQQQQQPPPPSQQQQQLHQLKSPQQHQQQLQQHQQQQQQQHHQQQHHQQQHQQQQQQHHQQQQPNESDVVPISTAMDTAIYDRDKQIYKCSTLRQGGKFDPKYKPSILNCPLPEIPKDAEQPKVESIYEQRQQAHHQNYSKTLQRPPMMLPPQMKAIPPPRIGTPTSPPPPVAQPLNESNGGVPSGLQNGGAVVGGGGANANEDTSLPPPPLEAQTEATKARMGAGPAANGKVLHNGGGGGSVGGGGGGAVDDDDDLPPPPPAITDESNYAVTEL", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9W5A5-1", "uniprot_id": "TTYH2_DROME", "id": "Q9W5A5-1", "name": "Protein movement modulator", "aln": "---------MEQPSILVKILHSIPHVNYTFRRVNDTFNPDSDVYLEPTNNKLQCQQKGIELQSLVILASIPAGLLIGSLLGLLLYLLTRCCDR------RQRKPSAQR-----------------CQSCSLVIITLMTCAAIGLGLYGNDDFHNGLLQAFGSGKSVEGLVLTLKRQTESIKHDLETRMAG--HKVEQLVEKPHYNQTVVMLLIETSRLVTENTSRAVASLDSMVHYFMKAK---------------------------GSENDTSLMGLLQLGEFYESIRWPATLAFLTVLLLLCTVLVIGVARRSRCTLIFFSVSGLFCIIICWLLAGVYLASSVAAGDFCMRPHDYMCRQVGMR-----SPYVDFLNCGTPR-NRFILRLNESRDLVDRARESVEHMQRMSQETYPHIDIQRTLNAMDNDLEITLRNLTTLSATLDRRTIDMHYEEALRGLCGGGLLGLSLMMVAGLLTSFLLTILVYADSHAWIYLTK-RPTLDADKSETAPLFPASNAPS--------------ASISPTAPLSTGTINRTLLHHQQASSGGGSGTLPGSGGGAGAGGGVGANGHNGVGPYRNGSAGLRQGLASPSSQSSHTSSTATYNNGTTSYHNSHQQHNN----HLYSNHYSHSNNHYNNTQHRTNPAAGAVAAAVGVVSSGQRSPSPPPVYDLVHGTRSGHHTLGRLPSHHQQSATYLPGPN---NGKYATLSKQCKTLESNDFY--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . .:: * :*: . :: . * * . * : :* ::.:... * **: : :*: ** : . . *..**:*:***.: :*: : : .: : :: . * : : ::. . . . . . * * ** . : * : *::* . ::*:*::*: ::.::. . : : .* *: .: *. .*:* * :: . . : * . * * *: : :. : : : : : : * :: *: : : * * :. : :. .: : :*** ..: ** : : .:::: :: : . :* : .. . . : . . ", "identical_positions": 51, "similar_positions": 134, "identity": "4.88%" }, { "cls_id": "homologset.agr.MGI:1889008", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q80XR2-1", "uniprot_id": "AT2C1_MOUSE", "id": "Q80XR2-1", "name": "Calcium-transporting ATPase type 2C member 1", "aln": "--------------------------------------MKVAR-------FQKIPNVENETMIP----------------------------------------VLTSKRASELAVSEVAGLLQADLQNGLNKS-EVSHRRAFHGWNEFDISEDEPLWKKYISQFKNP-LIMLLLASAVISILMRQFDDAVSITVAIVIVVTVAFVQEYRSEKSLEELSKLVPPECHCVREGKLEHTLARDLVPGDTVCLSVGDRVPADLRLFEAVDLSVDESSLTGETAPCSKVTAPQP-------AAN-GDLASRSNIAFMGTLVRCGKAKGIVIGTGENSEFGEVFKMMQAEEAPKTPLQKSMDLLGKQLSFYSFGIIGIIMLVGWLLGKDILEMFTISVSLAVAAIPEGLPIVVTVTLALGVMRMVKKRAIVKKLPIVETLGCCNVICSDKTGTLTKNEMTVTHILTSDGLHAEVTGVGYNQFGEVIVDGDVVHGFYNPAVSRIVEAGCVCNDAVIRNN--TLMGKPTEGALIALAMKMGLDGLQQDYIRKAEYPFSSEQKWMAVKCVHRTQQDRPEICFMKGAYEQVIKYCTTYNS--KGQTLALTQQQRDLYQQEKARMGSAGLRVLALASGPE-----------LGQLTFLGLVGIIDPPRTGVKEAVTTLIASGVSIKMITGDSQETAIAIASR----------------------------------------------------------LGLYSKTSQSVSGEEVDTMEVQHLSQIVPKVAVFYRASPRHKMKIIKSLQKNGAVVAMTGDGVNDAVALKAADIGVAMGQTGTDVCKEAADMILVDDDFQTIMSAIEEGKGIYNNIKNFVRFQLSTSIAALTLISLATLMNFPNPLNAMQILWINIIMDGPPAQSLGVEPVDKDVIRKPPRNWKDSILTKNLILKILVSSIIIVCGTLFVFWRELRDNVI--TPRDTTMTFTCFVFFDMFNALSSRSQTKSVFEIGLCSNKMFCYAVLGSIMGQLLVIYFPPLQKVFQTESLSILDLLFLLGLTSSVCIVSEIIKKVERSREKVQKNAGSASSSFLEV", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q64566-1", "uniprot_id": "AT2C1_RAT", "id": "Q64566-1", "name": "Calcium-transporting ATPase type 2C member 1", "aln": "--------------------------------------MKVAR-------FQKIPNVENETMIP----------------------------------------VLTSKRASELAVSEVAGLLQADLQNGLNKS-EVSHRRAFHGWNEFDISEDEPLWKKYISQFKNP-LIMLLLASAVISVLMRQFDDAVSITVAILIVVTVAFVQEYRSEKSLEELSKLVPPECHCVREGKLEHTLARDLVPGDTVCLSVGDRVPADLRLFEAVDLSIDESSLTGETTPCSKVTAPQP-------AATNGDLASRSNIAFMGTLVRCGKAKGIVIGTGENSEFGEVFKMMQAEEAPKTPLQKSMDLLGKQLSFYSFGIIGIIMLVGWLLGKDILEMFTISVSLAVAAIPEGLPIVVTVTLALGVMRMVKKRAIVKKLPIVETLGCCNVICSDKTGTLTKNEMTVTHILTSDGLHAEVTGVGYNQFGEVIVDGDVVHGFYNPAVSRIVEAGCVCNDAVIRNN--TLMGKPTEGALIALAMKMGLDGLQQDYIRKAEYPFSSEQKWMAVKCVHRTQQDRPEICFMKGAYEQVIKYCTTYNS--KGQTLALTQQQRDLYQQEKAQMGSAGLRVLALASGPD-----------LGQLTLLGLVGIIDPPRTGVKEAVTTLIASGVSIKMITGDSQETAIAIASR----------------------------------------------------------LGLYSKTSQSVSGEEVDTMEVQHLSQIVPKVAVFYRASPRHKMKIIKSLQKNGSVVAMTGDGVNDAVALKAADIGVAMGQTGTDVCKEAADMILVDDDFQTIMSAIEEGKGIYNNIKNFVRFQLSTSIAALTLISLATLMNFPNPLNAMQILWINIIMDGPPAQSLGVEPVDKDVIRKPPRNWKDSILTKNLILKILVSSIIIVCGTLFVFWRELRDNVI--TPRDTTMTFTCFVFFDMFNALSSRSQTKSVFEIGLCSNKMFCYAVLGSIMGQLLVIYFPPLQKVFQTESLSILDLLFLLGLTSSVCIVSEIIKKVERSREKTQKNTTSTPSSFLEV", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P98194-1", "uniprot_id": "AT2C1_HUMAN", "id": "P98194-1", "name": "Calcium-transporting ATPase type 2C member 1", "aln": "--------------------------------------MKVAR-------FQKIPNGENETMIP----------------------------------------VLTSKKASELPVSEVASILQADLQNGLNKC-EVSHRRAFHGWNEFDISEDEPLWKKYISQFKNP-LIMLLLASAVISVLMHQFDDAVSITVAILIVVTVAFVQEYRSEKSLEELSKLVPPECHCVREGKLEHTLARDLVPGDTVCLSVGDRVPADLRLFEAVDLSIDESSLTGETTPCSKVTAPQP-------AATNGDLASRSNIAFMGTLVRCGKAKGVVIGTGENSEFGEVFKMMQAEEAPKTPLQKSMDLLGKQLSFYSFGIIGIIMLVGWLLGKDILEMFTISVSLAVAAIPEGLPIVVTVTLALGVMRMVKKRAIVKKLPIVETLGCCNVICSDKTGTLTKNEMTVTHIFTSDGLHAEVTGVGYNQFGEVIVDGDVVHGFYNPAVSRIVEAGCVCNDAVIRNN--TLMGKPTEGALIALAMKMGLDGLQQDYIRKAEYPFSSEQKWMAVKCVHRTQQDRPEICFMKGAYEQVIKYCTTYQS--KGQTLTLTQQQRDVYQQEKARMGSAGLRVLALASGPE-----------LGQLTFLGLVGIIDPPRTGVKEAVTTLIASGVSIKMITGDSQETAVAIASR----------------------------------------------------------LGLYSKTSQSVSGEEIDAMDVQQLSQIVPKVAVFYRASPRHKMKIIKSLQKNGSVVAMTGDGVNDAVALKAADIGVAMGQTGTDVCKEAADMILVDDDFQTIMSAIEEGKGIYNNIKNFVRFQLSTSIAALTLISLATLMNFPNPLNAMQILWINIIMDGPPAQSLGVEPVDKDVIRKPPRNWKDSILTKNLILKILVSSIIIVCGTLFVFWRELRDNVI--TPRDTTMTFTCFVFFDMFNALSSRSQTKSVFEIGLCSNRMFCYAVLGSIMGQLLVIYFPPLQKVFQTESLSILDLLFLLGLTSSVCIVAEIIKKVERSREKIQKHVSSTSSSFLEV", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AC58HKV0-1", "uniprot_id": "A0AC58HKV0_DANRE", "id": "A0AC58HKV0-1", "name": "Calcium-transporting ATPase", "aln": "--------------------------------------MCRAGGPPGTWLVECQPDSKDETMVP----------------------------------------VLTSKKASELPVNEVACALQADLQFGLNRE-EVERRRTYHGWNEFDISEDEPLWKKYLSQFKDP-LILLLLSSAVISVLMRQFDDAVSITVAIIIVVTVAFVQEYRSEKSLEELGKLVPPECHCIREGHLEHLLARELVPGDTVCLSVGERVPADLRLFESTDLAVDESSLTGETTPCTKTSAPQP-------AATNGDIASRSNIAFMGTLVRCGKAKGIVIGTGEDSEFGEVFKMMQAEEAPKTPLQKSMDLLGKQLSLYSLGIIGVIMFVGWLQGKYILDMFTIGVSLAVAAIPEGLPIVVTVTLALGVMRMVKKRAIVKKLPIVETLSCCNVICSDKTGTLTKNEMTVTHLFTSDGQHAEVTGIGYNNSGEILMDGEVVHGISNTSISKIVEVGCVCNDAMIRHN--TLMGRPTEGALIALAMKMGLEGLQHEFVRLEEIPFTSEQKWMAVRVVHRTQRDKPGLFYVKGAYEQVIRFCTSYNS--KGVTMPLNNQQRDFYQQQKSYMGSGGLRVLAFASGSE-----------MGSLTFLGLVGIIDPPRAGVKEAVATLISSGVAVKMVTGDSEETAVAIASR----------------------------------------------------------LGLYTKGSQCLSGDEVDQMDIQHLSQIVHRVVVFYRASPRHKLKIVKSLQNIGAVVAMTGDGVNDAVALKAADIGVAMGQTGTDVCKEAADMILVDDDFQTILSAIEEGKGIYNNIKNFVRFQLSTSIAALTLISLATLLNFPTPLNAMQILWINIIMDGPPAQSLGVEPVDWDVIRKPPRNVRDSIITRSLIVKILVSAFIIVCGTLFVFWRELRDNEI--TPRDTTMTFTCFVFFDMFNALSSRSQTRMVHEMGLCSNRMFCYAVLGSIMGQLLVIYFPPLQSVFQTESLSILDLLLLFGLTSSVCVVSEIIKKIERLRCGSEK-MSDMDSEFHDV", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "M9PG15-1", "uniprot_id": "M9PG15_DROME", "id": "M9PG15-1", "name": "P-type Ca(2+) transporter", "aln": "MSKTPKPLTSKRRTSPASPGSTVLIESPTTSSGVRNRRSKIKGVDSKPNPQRTISHVKDSRAVPQNVKPGKVADMKDCKEPDEDNVDQQNGNIIQTGLTLTPEMLLSTSESSTHSASEVAGRLQVDVRTGLKWT-EAKYRAKIIGHNELLLVAEDPTWKKYIEQFRNP-LILLLLGSALVSVIMKQFDDAVSITIAILIVVTVAFIQEYRSEKSLEELKKLVPPECHCLREGRLDTFLARELVPGDIVHLNVGDRVPADVRLFEAVDLSIDESSFTGETEPARKITDVLLN------NTNVKDHSNMKNIAFMGTLVRCGNGKGIVVSTGERSEFGEVFKMMQAEEAPKTPLQKSMDILGAQLSFYSFLIIGVIMLLGWLQGKPLSEMFNISVSLAVAAIPEGLPIVVTVTLALGVMRMAKRNSIVKKLPTVETLGCVNVICSDKTGTLTKNEMTATIIITSDGYMADVTGAGYNDQGEIHIRHCNNVEMAKTNITNLLEIGAVCNNAYIQNG--TLLGQPTEGALVAVAMKNGMYATAENYVRIQEYPFSSEQKMMAVKCIHKYNNNKEEIFFAKGALETLLPQCTKYQF--GTQTVPLTKQNEAEFLAEAYEIGRKGLRVLALAKGRS-----------MQDLIYCGLVGITDPPRPLVRESIEMLMQSGVRVKMVTGDAQETALAIDPSRRLQAVPTHAIPAWPTAGGVPLCSASACCSTNCLENAMKEIYLTALAQQGLPLVTANLIGIDTIHHQTLSGQEMDQMNEHQLDKVANNVSVFYRVSPRHKLEIVKSLQRSGNIVGMTGDGVNDGVALKKADIGIAMGKNGTDVCKEAADMILVNDDFHTIIAAIEEGKGIFYNIRNFVRFQLSTSIAALALIALATLMDIANPLNAMQILWINIIMDGPPAQSLGVEPVDHDVLKQKPRNVKQPMITKSVVVNVLLSASIIVLGTLWVFQREMADGTLGKTKRDTTMTFTCFVFFDMFNALSCRSQTKSVFTIGLTTNRMFLLAVAFSIIGQMLVVYFPPLQMVFQTEALTPYDIFFLVSLTSSVLVVSEIKKWFER---TMERKMYSTRSELDFV", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P13586-1", "uniprot_id": "ATC1_YEAST", "id": "P13586-1", "name": "Calcium-transporting ATPase 1", "aln": "---------------------------------MSDNPFNASLLDEDSNREREILDATAEALSK----------------------------------------PSPSLEYCTLSVDEALEKLDTDKNGGLRSSNEANNRRSLYGPNEITVEDDESLFKKFLSNFIEDRMILLLIGSAVVSLFMGNIDDAVSITLAIFIVVTVGFVQEYRSEKSLEALNKLVPAECHLMRCGQESHVLASTLVPGDLVHFRIGDRIPADIRIIEAIDLSIDESNLTGENEPVHKTSQTIEKSSFNDQPNSIVPISERSCIAYMGTLVKEGHGKGIVVGTGTNTSFGAVFEMMNNIEKPKTPLQLTMDKLGKDLSLVSFIVIGMICLVGIIQGRSWLEMFQISVSLAVAAIPEGLPIIVTVTLALGVLRMAKRKAIVRRLPSVETLGSVNVICSDKTGTLTSNHMTVSKLWCLDSMSNKLNVLSLDKNKKTKNSNGNLKNYLTEDVRETLTIGNLCNNASFSQEHAIFLGNPTDVALLEQLANFEMPDIRNTVQKVQELPFNSKRKLMATKILNPVDN--KCTVYVKGAFERILEYSTSYLKSKGKKTEKLTEAQKATINECANSMASEGLRVFGFAKLTLSDSSTPLTEDLIKDLTFTGLIGMNDPPRPNVKFAIEQLLQGGVHIIMITGDSENTAVNIAKQIG--------------------------------------------------------IPVIDPKLSVLSGDKLDEMSDDQLANVIDHVNIFARATPEHKLNIVRALRKRGDVVAMTGDGVNDAPALKLSDIGVSMGRIGTDVAKEASDMVLTDDDFSTILTAIEEGKGIFNNIQNFLTFQLSTSVAALSLVALSTAFKLPNPLNAMQILWINILMDGPPAQSLGVEPVDHEVMKKPPRKRTDKILTHDVMKRLLTTAACIIVGTVYIFVKEMAEDGK-VTARDTTMTFTCFVFFDMFNALACRHNTKSIFEIGFFTNKMFNYAVGLSLLGQMCAIYIPFFQSIFKTEKLGISDILLLLLISSSVFIVDELRKLWTR------KKNEEDSTYFSNV", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . . . .: . . ...*. *:.* . **. *.. * * **: : ::. :**::.:* : :*:**:.**::*::* ::*******:**.*****.*:********** * ****.*** :* *: . ** ***** * : :*:*:***:*::*: **::***.:***. * * : . :. . **:*****: *:.**:*:.** :.** **:**: * ****** :** ** :**: *: :**:* ::* : *: :** *.**************:*********:**.*:.:**::** ****.. ************.*.**.: : *. .:. . :. : . : . : * :**:* : : ::*.**: **: : : . : * **.*::* **.: :: :. : *** * :: .*.* * *.: :. :. ****:.:*. : .* **:*: ****. *: :: *: .** : *:***:::**: * : : . :**:::* *. .:* :: .* :* *.:*.**::*:::*:. * :*.********. *** :***::**: ****.***:**:*.:*** **::********: **:**: ******:***:*::*:* :.:..************:*************** :*::: **: : ::*:.:: .:* :: *: **:::* :*: :. * *******************:.* :*: :. :*: :*:** ** *::**: .:*:* :* :*:** * *:::*. ::*** :* *: * * : . : : *", "identical_positions": 374, "similar_positions": 274, "identity": "34.38%" }, { "cls_id": "homologset.agr.MGI:1889011", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q91ZZ3-1", "uniprot_id": "SYUB_MOUSE", "id": "Q91ZZ3-1", "name": "Beta-synuclein", "aln": "MDVFMKGLSMAKEGVVAAAEKTKQGVTEAAEKTKEGVLYVGSKT-SGVVQGVASVAEKTKEQASHLGGAVFSGAGNIAAATGLVKKEEFPTDLKPEEVAQEAAEEPLIEPLMEPEGESYEDSPQEEYQEYEPEA---", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q63754-1", "uniprot_id": "SYUB_RAT", "id": "Q63754-1", "name": "Beta-synuclein", "aln": "MDVFMKGLSMAKEGVVAAAEKTKQGVTEAAEKTKEGVLYVGSKTKEGVVQGVASVAEKTKEQASHLGGAVFSGAGNIAAATGLVKKEEFPTDLKPEEVAQEAAEEPLIEPLMEPEGESYEDSPQEEYQEYEPEAKGP", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q16143-1", "uniprot_id": "SYUB_HUMAN", "id": "Q16143-1", "name": "Beta-synuclein", "aln": "MDVFMKGLSMAKEGVVAAAEKTKQGVTEAAEKTKEGVLYVGSKTREGVVQGVASVAEKTKEQASHLGGAVFSGAGNIAAATGLVKREEFPTDLKPEEVAQEAAEEPLIEPLMEPEGESYEDPPQEEYQEYEPEA---", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "******************************************** .***************************************:***********************************.************ ", "identical_positions": 130, "similar_positions": 3, "identity": "94.89%" }, { "cls_id": "homologset.agr.MGI:1889023", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8N9N5-1", "uniprot_id": "BANP_HUMAN", "id": "Q8N9N5-1", "name": "Protein BANP", "aln": "---------------------------------------------MMSEHDLADVVQIAVEDLSPDHP-----------VVLENHVVTDEDEPALKRQRLEINCQDPSIK--------TICLRLDSIEAKLQALEATCKSLEEKLDLVTNKQHSPIQVPMVAGSPLGATQTCNKVRCVVPQTTVILNNDRQNAIVAKMEDPLSNRAPDSLENVISNAVPGRRQNTIVVKVPGQEDSHHEDGESGSEASDSVSSCGQAGSQSIGSNVTLITLNSEEDYPNGTWLGDENNPEMRVRCAIIPSDMLHISTNCRTAEKMALTLLDYLFHREVQAVSNLSGQGKHGKKQLDPLTIYGIRCHLFYKFGITESDWYRIKQSIDSKCRTAWRRKQRGQSLAVKSFSRRTPNSSSYCPSEPMMSTPPPASELPQPQPQPQALHYALANA-QQVQIHQIGEDGQVQVG---HLHIAQVPQGEQVQITQDSEGNLQIH--HVGQDGQLLEATRIPCLLAP-SVFKASSG-------------------QVLQGAQLIAVASSDPAAAGVDGSPLQGSDIQVQYVQLAPVSDHTAGAQTAEALQPTLQPEM---------QLEHG-AIQIQ----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8VBU8-1", "uniprot_id": "BANP_MOUSE", "id": "Q8VBU8-1", "name": "Protein BANP", "aln": "---------------------------------------------MMSEQDLADVVQIAVEDLSPDHP-----------VVLENHVVTDDDEPALKRQRLEINCQDPSIKSFLYSINQTICLRLDSIEAKLQALEATCKSLEEKLDLVTNKQHSPIQVPMVAGSPLGATQTCNKVRCVVPQTTVILNNDRQNAIVAKMEDPLSNRAPDSLENIISNAVPGRRQNTIVVKVPGQDDSHNEDGESGSEASDSVSNCGQPGSQNIGSNVTLITLNSEEDYPNGTWLGDENNPEMRVRCAIIPSDMLHISTNCRTAEKMALTLLDYLFHREVQAVSNLSGQGKHGKKQLDPLTIYGIRCHLFYKFGITESDWYRIKQSIDSKCRTAWRRKQRGQSLAVKSFSRRTPSSSSYSASETMMGTPPPTSELQQSQP--QALHYALANA-QQVQIHQIGEDGQVQVIPQGHLHIAQVPQGEQVQITQDSEGNLQIH--HVGQDGQSWGLCQNPIPVSGDSVAQANPSQLWPLGGDTLDLPAGNEMIQVLQGAQLIAVASSDPAATGVDGSPLQGSDIQVQYVQLAPVSDHTAAAQTAEALQPTLQPDM---------QLEHG-AIQIQ----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8I6A1X0-1", "uniprot_id": "A0A8I6A1X0_RAT", "id": "A0A8I6A1X0-1", "name": "Protein BANP", "aln": "MFTGVRRRKRAQEAPSAGSAPCPTGPSLEPRAQGACAEGAAQAVGRCSQRLRRAAASLARTDAIIASPRQTPREFRSPHVVLENHVVTDDDEPALKRQRLEINCQDPSIKSFLYSINQTICLRLDSIEAKLQALEATCKSLEEKLDLVTNKQHSPIQVPMVAGSPLGATQTCNKVRCAVP---------------------------------------GRRQNTIVVKVPGQDDSHNEDGESGSEASDSVSNCGQPGSQNIGSNVTLITLNSEEDYPNGTWLGDENNPEMRVRCAIIPSDMLHISTNCRTAEKMALTLLDYLFHREVQAVSNLSGQGKHGKKQLDPLTIYGIRCHLFYKFGITESDWYRIKQSIDSKCRTAWRRKQRGQSLAVKSFSRRTPSSSSYSASETMMGTPPPTSELQQSQP--QALHYALANA-QQVQIHQIGEDGQVQVG---HLHIAQVPQGEQVQITQDSEGNLQIH--HVGQDGQSWGLCQNPIPVSGDSVAQANPSQLWPLGGDTLDLPAGNEMIQVLQGAQLIAVASSDPAATGVDGSPLQGSDIQVQYVQLAPVSDHTAATQTAEALQPTLQPEM---------QLEHG-AIQIQ----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q502P7-1", "uniprot_id": "BANP_DANRE", "id": "Q502P7-1", "name": "Protein BANP", "aln": "---------------------------------------------MMSEQGLVEIVQIAVADLNHEGHQT---------DVLENN--EDSDQPGRKRARIEIS-QETSIKSMLISISQAICQRLDSMEAKLQVLEVTCRGLVEKLDTVMGKNQSTTQVPMVSGSPFGATQTCDKVRCVVPQTNVIVSGDR------AKTEETSPRTSDSLENLLSNTVGRGRQKTIVLKVPVQEEIQ-DDQESGSETSDSVSNSGQPQNN---NNVTLITLNSEEDYPTGTWLGDENNPEMRVRCPVSPADMLHISTNCRTAEKMALTLLDYLFHREVQAVSNLSGQGKHGKKQLDPLMIYGIRCHLFFKFAITESDWYRIKQSIDSKCRTAWRRKQRGQSLAVKSFSRRTPASQSSSDG----VSAAETSAIETSTQ--QALHYALAGATQQVQIHRIGEDGQVQVIPQGHLHIAQVPQGEQVQITQDSEGNLQIHQVHVGQDGQ----------------------------------------VNVLRGPQLIAVASTD-GTGGVDASPLQANDIQVQYVQLGTVTDHTGAVQ-AEALTPALQAEMDVKEAIQLQQAENGEVVQIQMPGT", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *:: ..:* * ****: *.*:*. ** *:**. *:.*** :** ****:*****.**.**:.* **** * .*::*. *****:***:******:****.** **:***:*** *:: : :* *****:*****..**. .: .**************.****************.: *:************************************************ *********:**.**************************************** *.* . . :.. :* : . ********.* ******:********* ************************** ******* :**:*.*******:* .: ***.****..*********..*:***...* **** *:**.:* * *:* .:*** ", "identical_positions": 320, "similar_positions": 78, "identity": "51.36%" }, { "cls_id": "homologset.agr.MGI:1889024", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9ES58-1", "uniprot_id": "MO2R1_RAT", "id": "Q9ES58-1", "name": "Cell surface glycoprotein CD200 receptor 1", "aln": "MLCFWRTSHVAVLLIWGVFAAE--------------------------SSCPDKNQTMQNNSST-MTEVNTTVFVQMGKKALLCCPSISLTKVILITWTITLRGQPSCIISYKADTRETHESNCSDRSITWASTPDLAPDLQISAVALQHEGRYSCDIAVPDGNFQNIYDLQVLVPPEVTHFPGENRTAVCEAIAGKPAAQISWTPDG-DCVAKNESHSNGTVTVRSTCHWEQSHVSVVFCVVSHLTTGNQSLSIELG-----RGGDQLLGSYIQYIIPS--IIILIIIGCICLLKISGCRKCKLPKSGATPDIEEDEMQPYASYTEKSNPLYDTVTTTEAHPASQGKVNGTDCLTLSAMGI", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9ES57-1", "uniprot_id": "MO2R1_MOUSE", "id": "Q9ES57-1", "name": "Cell surface glycoprotein CD200 receptor 1", "aln": "MFCFWRTSALAVLLIWGVFVAG--------------------------SSCTDKNQTTQNNSSSPLTQVNTTVSVQIGTKALLCCFSIPLTKAVLITWIIKLRGLPSCTIAYKVDT-KTNETSCLGRNITWASTPDHSPELQISAVTLQHEGTYTCETVTPEGNFEKNYDLQVLVPPEVTYFPEKNRSAVCEAMAGKPAAQISWSPDG-DCVTTSESHSNGTVTVRSTCHWEQNNVSDVSCIVSHLT-GNQSLSIELS-----RGGNQSLRPYIPYIIPS--IIILIIIGCICLLKISGFRKCKLPKLEATSAIEEDEMQPYASYTEKSNPLYDTVTKVEAFPVSQGEVNGTDCLTLSAIGI", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8TD46-4", "uniprot_id": "MO2R1_HUMAN", "id": "Q8TD46-4", "name": "Cell surface glycoprotein CD200 receptor 1", "aln": "MLCPWRTANLGLLLILTIFLVAEAEGAAQPNNSLMLQTSKENHALASSSLCMDEKQITQN-YSKVLAEVNTSWPVKMATNAVLCCPPIALRNLIIITWEIILRGQPSCTKAYKKETNETKETNCTDERITWVSRPDQNSDLQIRTVAITHDGYYRCIMVTPDGNFHRGYHLQVLVTPEVTLFQNRNRTAVCKAVAGKPAAHISWIPEG-DCATKQEYWSNGTVTVKSTCHWEVHNVSTVTCHVSHLT-GNKSLYIEL---LPVPGAKKSAKLYIPYIILT--IIILTIVGFIWLLKVNGCRKYKLNKTESTPVVEEDEMQPYASYTEKNNPLYDTTNKVKASEALQSEVD-TDLHTL-----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6Q8B3-1", "uniprot_id": "MO2R2_HUMAN", "id": "Q6Q8B3-1", "name": "Cell surface glycoprotein CD200 receptor 2", "aln": "MSAPR-------LLISIIIMVS-----------------------ASSSSCMGGKQMTQN-YSTIFAEGNISQPVLMDINAVLCCPPIALRNLIIITWEIILRGQPSCTKAYKKETNETKETNCTVERITWVSRPDQNSDLQIRPVDTTHDGYYRGIVVTPDGNFHRGYHLQVLVTPEVNLFQSRNITAVCKAVTGKPAAQISWIPEGSILATKQEYWGNGTVTVKSTCPWEGH-KSTVTCHVSHLT-GNKSLSVKLNSGLRTSGSPALSLLIILYVKLSLFVVILVTTGFVFFQRINHVRKVL----------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* . *** :: . * * . :* ** *. ::: * : * : :*:*** .*.* : ::*** * *** *** :** :* :*:*:.* . ***.* ** .:*** .* *:* * ..*:***.. *.*****.***. * .* :***:*::*****:*** *:* .:..* .******:*** ** * * * ***** **:** ::* *. * *: : ::** * : : ::. ** ", "identical_positions": 109, "similar_positions": 65, "identity": "30.11%" }, { "cls_id": "homologset.agr.MGI:1889073", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZMP9-1", "uniprot_id": "D3ZMP9_RAT", "id": "D3ZMP9-1", "name": "Ran guanine nucleotide release factor", "aln": "-----------------------------MEPARNCPLFGGAFSAILPRGAIDVSDLRPVPDNQEVFCHP-----------VTDQSLIIELLELQAHVQGEAAARYHFEDVGGVQGARS---VHVLSVQPLCLENLSLRGCCQDAWFLSGKQQVAKENQQVAKDVTLHQALLRLPQYQTDLLLTFNQPPCHSR-PLGPE-NLSCPPWSLGN-FEQLVTSLTLHDPNLFGPQ", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9JIB0-1", "uniprot_id": "MOG1_MOUSE", "id": "Q9JIB0-1", "name": "Ran guanine nucleotide release factor", "aln": "-----------------------------MEPNRNCPLFGGAFSAILPTGAIDVSDLRPVPDNQEVFCHP-----------VTDQSLIIELLELQAHVQGEAAARYHFEDVGRVQGARA---VHVLSVQPLCLENLSLRGCCQDAWSLSGKQQVAKENQQVAKDVTLHQALLRLPQYQTDLLLTFNQPPCHSR-SLGPE-NLSCPPWSLSN-FEQLVTSLTLHDPNLFGPQ", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9HD47-1", "uniprot_id": "MOG1_HUMAN", "id": "Q9HD47-1", "name": "Ran guanine nucleotide release factor", "aln": "-----------------------------MEPTRDCPLFGGAFSAILPMGAIDVSDLRPVPDNQEVFCHP-----------VTDQSLIVELLELQAHVRGEAAARYHFEDVGGVQGARA---VHVESVQPLSLENLALRGRCQEAWVLSGKQQIAKENQQVAKDVTLHQALLRLPQYQTDLLLTFNQPPPDNRSSLGPE-NLSPAPWSLGD-FEQLVTSLTLHDPNIFGPQ", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A3KPP3-1", "uniprot_id": "MOG1_DANRE", "id": "A3KPP3-1", "name": "Ran guanine nucleotide release factor", "aln": "-----------------------------MSR----PLFGGALSAVFPSSVMDISELRQIPDNQEVFAHS-----------QTDQSIIIELLEYQSQVQDADAARYHFEDVAGSNKAIENGTWEVRVVEQVPQSEISMQ-ECSSAWLLSGAQLVSKFNEEAKNTVNVHQCLFRLPQFTTDILMTFNDPVFINPLSSSAAGNMEAIPWTLQD-FQGVLQSLRLLDSGVFG--", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P47123-1", "uniprot_id": "MOG1_YEAST", "id": "P47123-1", "name": "Nuclear import protein MOG1", "aln": "MKIEKASHISQPVQLSTCTLIDTYPGHQGSMNNKEVELYGGAITTVVPPGFIDASTLREVPDTQEVYVNSRRDEEEFEDGLATNESIIVDLLETVDKSDLKEAWQFHVEDLTELNGTTK---------WEALQEDTVQQGTKFTGLVMEVANKWGK--PDLAQTVVIGVALIRLTQFDTDVVISINVPLTKEEASQASNKELPARCHAVYQLLQEMVRKFHVVDTSLFA--", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *:***::::.* . :* * ** :**.***: :. *::*:*::*** : * ::*.**: : : .: : . :. : .* : : * : .*:**.*: **:::::* * . . .. :: :: : :: :: .: : *..:*. ", "identical_positions": 36, "similar_positions": 65, "identity": "15.58%" }, { "cls_id": "homologset.agr.MGI:1889205", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9WVJ3-1", "uniprot_id": "CBPQ_MOUSE", "id": "Q9WVJ3-1", "name": "Carboxypeptidase Q", "aln": "MRSLFFLFI--VHLLALGSGKAVFKNGVSQRTFREIKEEIANYEDVAKAIINLAVYGKYQNRSYERLGLLVDTVGPRLSGSKNLEKAIQIMYQNLQQDGLENVHLEQVRIPHWERGEESAVMLEPRIHKMAILGLGSSIGTPPGGITAEVLVVASFDELQRRASEARGKIIVYNQPYTGYEKTVQYRVQGAVEAAKVGAVASLIQSVASFSIYSPHTGIQKYQDGVPKIPTACITVEDAEMMSRMASRGNKIVIHLEMGAKTYPDTDSFNTVAEITGSMYPEEVVLVSGHLDSWDVGQGALDDGGGAFISWEALSLVKDLGLRPKRTLRLVLWTAEEQGGIGASQYYELHKANISKYSLVMEADSGTFLPTGLQFTGSDKARAIMKEVMNLLQPLNVTKVFSNGEGTDINFWIQAGVPGASLRDDLYKYFFFHHSHGDTMTVMDPKQMNVAAAVWAVVAYVVADMDEMLPRS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6IRK9-1", "uniprot_id": "CBPQ_RAT", "id": "Q6IRK9-1", "name": "Carboxypeptidase Q", "aln": "MRFLFFLFVAVVHLFSLGSGKAIYKSGVSQRTFQEIKEEIANYEDVAKAIINLAVYGKYQNRSYERLGLLVDTVGPRLSGSKNLEKAIQIMYQNLQQDGLENVHLEQVRIPHWERGEESAVMVVPRIHKLAILGLGGSIGTPPEGITAEVLVVASFVELQRRASEARGKIVVYNQPYTDYGKTVQYRERGAVEAAKVGAVASLIRSVASFSIYSPHTGHQGYQDGVPKIPTACITIEDAEMMSRMASRGDKIVIHLKMGAKTYPDTDSFNTVAEITGSKYPEEVVLVSGHLDSWDVGQGALDDGGGAFISWEALSLVKDLGLRPKRTLRLVLWTAEEQGGVGASQYYELHKANISKYSLVMEADSGTFLPTGLQFTGSDKARAIMKEVMSLLQPLNITKVFNDAEGTDINFWIQAGVPGASLRDDLYKYFFFHHSHGDTMTAMDPKQMNVAAAVWAVVAYVVADMEEMLPRS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9Y646-1", "uniprot_id": "CBPQ_HUMAN", "id": "Q9Y646-1", "name": "Carboxypeptidase Q", "aln": "MKFLIFAFFGGVHLLSLCSGKAICKNGISKRTFEEIKEEIASCGDVAKAIINLAVYGKAQNRSYERLALLVDTVGPRLSGSKNLEKAIQIMYQNLQQDGLEKVHLEPVRIPHWERGEESAVMLEPRIHKIAILGLGSSIGTPPEGITAEVLVVTSFDELQRRASEARGKIVVYNQPYINYSRTVQYRTQGAVEAAKVGALASLIRSVASFSIYSPHTGIQEYQDGVPKIPTACITVEDAEMMSRMASHGIKIVIQLKMGAKTYPDTDSFNTVAEITGSKYPEQVVLVSGHLDSWDVGQGAMDDGGGAFISWEALSLIKDLGLRPKRTLRLVLWTAEEQGGVGAFQYYQLHKVNISNYSLVMESDAGTFLPTGLQFTGSEKARAIMEEVMSLLQPLNITQVLSHGEGTDINFWIQAGVPGASLLDDLYKYFFFHHSHGDTMTVMDPKQMNVAAAVWAVVSYVVADMEEMLPRS", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*: *:* *. ***::* ****: *.*:*:***.*******. ************** ********.*********************************:**** ***************: *****:******.****** *********:** *************:****** .* :***** :**********:****:************* * **************:***********:* ****:*:********************* ***:*****************:***************:***********************:** ***:***.***:******:*:*************:******:***.******:*:*:...****************** ******************.****************:******:******", "identical_positions": 402, "similar_positions": 48, "identity": "85.17%" }, { "cls_id": "homologset.agr.MGI:1889206", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q920G0-1", "uniprot_id": "SKAP2_RAT", "id": "Q920G0-1", "name": "Src kinase-associated phosphoprotein 2", "aln": "MPNPGSTSSPGSIPEEIRNLLADVETFVADTLKGENLSKKAKEKRDSLIKKIKDVKSVYPQEFQDKGDAEEGDEYDDPFAGPPDTISLASERYDKDDDGPSDGNQ-FPPIAAQDLSFVIKAGYLEKRRKDHSFLGFEWQKRWCALSKTVFYYYGSDKDKQQKGEFAIEGYDVRMNNTLRKDAKKDCCFEICAPDKRIYQFTAASPKDAEEWVQQLKFILQDMGSDVIPEDEDEKGDLYDDVDHPVPVSSPQRS-QPIDDEIYEELPEEEEDTAS-VKMDEQGKGSRDSVQHPSG-DKSTDYANFYQGLWDCTGSLSDELSFKRGDVIYILSKEYNRYGWWVGEMQGAIGLVPKAYLMEMYDI", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q3UND0-1", "uniprot_id": "SKAP2_MOUSE", "id": "Q3UND0-1", "name": "Src kinase-associated phosphoprotein 2", "aln": "MPNPSCTSSPGPLPEEIRNLLADVETFVADTLKGENLSKKAKEKRESLIKKIKDVKSVYLQEFQDKGDAEDGDEYDDPFAGPADTISLASERYDKDDDGPSDGNQ-FPPIAAQDLPFVIKAGYLEKRRKDHSFLGFEWQKRWCALSKTVFYYYGSDKDKQQKGEFAIDGYDVRMNNTLRKDGKKDCCFEICAPDKRIYQFTAASPKDAEEWVQQLKFILQDLGSDVIPEDDEERGELYDDVDHPAAVSSPQRS-QPIDDEIYEELPEEEEDTAS-VKMDEQGKGSRDSVHHTSG-DKSTDYANFYQGLWDCTGALSDELSFKRGDVIYILSKEYNRYGWWVGEMKGAIGLVPKAYLMEMYDI", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O75563-1", "uniprot_id": "SKAP2_HUMAN", "id": "O75563-1", "name": "Src kinase-associated phosphoprotein 2", "aln": "MPNPSSTSSPYPLPEEIRNLLADVETFVADILKGENLSKKAKEKRESLIKKIKDVKSIYLQEFQDKGDAEDGEEYDDPFAGPPDTISLASERYDKDDEAPSDGAQ-FPPIAAQDLPFVLKAGYLEKRRKDHSFLGFEWQKRWCALSKTVFYYYGSDKDKQQKGEFAIDGYSVRMNNTLRKDGKKDCCFEISAPDKRIYQFTAASPKDAEEWVQQLKFVLQDMESDIIPEDYDERGELYDDVDHPLPISNPLTSSQPIDDEIYEELPEEEEDSAP-VKVEEQRKMSQDSVHHTSG-DKSTDYANFYQGLWDCTGAFSDELSFKRGDVIYILSKEYNRYGWWVGEMKGAIGLVPKAYIMEMYDI", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6PG29-1", "uniprot_id": "SKAP2_DANRE", "id": "Q6PG29-1", "name": "Src kinase-associated phosphoprotein 2", "aln": "MR---------SVPEDFTTLISDLETFLTDVLKGENLSKKAKEKKDAFIKRIKDVKTSYAQEFKDRRDEE-FPEPDE--ADTNDGGSLHSEQTDRDDENAYDGVQQSPPVAAQDLQAVLKSGYLEKRRKDHSFFGNEWQKRWCALNNSIFYYYGSEKDKQQKGEFNIVGYTVKMNNTLRKDAKRDCCFEVSAPDKRVYQFCAASEKEAKEWVEHIDFLIKDLG-GIIPEDEEEYDDCLSMSQSEVAILP--------DDDIYEELPEEDVPQPSKPKVTLVNKPPPPATPVTAAVNKSTDYANYFQGLWDCIGDQPDELSFKRGDTIYILSKEYDMFGWWVGEMKGVIGIVPKEYLLELYVL", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* .:**:: .*::*:***::* *************::::**:*****: * ***:*: * * * *: *.. * ** **: *:**: . ** * **:***** *:*:************:* *********.:::******:********* * ** *:********.*:*****:.*****:*** *** *:*:***:::.*:::*: .:**** :* .: . : .: **:********: .. *: * . :. .:. :*******::****** * .*********.********: :*******:*.**:*** *::*:* :", "identical_positions": 196, "similar_positions": 84, "identity": "54.14%" }, { "cls_id": "homologset.agr.MGI:1889208", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P61025-1", "uniprot_id": "CKS1_MOUSE", "id": "P61025-1", "name": "Cyclin-dependent kinases regulatory subunit 1", "aln": "----------------------MSHKQIYYSDKYDDEEFEYRHVMLPKDIAKLVP---------KTHLMSESEWRNLGVQQSQGWVHYMIHEPEPHILLFRR---PLPKKPKK----------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P61024-1", "uniprot_id": "CKS1_HUMAN", "id": "P61024-1", "name": "Cyclin-dependent kinases regulatory subunit 1", "aln": "----------------------MSHKQIYYSDKYDDEEFEYRHVMLPKDIAKLVP---------KTHLMSESEWRNLGVQQSQGWVHYMIHEPEPHILLFRR---PLPKKPKK----------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F1M990-1", "uniprot_id": "F1M990_RAT", "id": "F1M990-1", "name": "Cyclin-dependent kinases regulatory subunit", "aln": "----------------------MSHKQIYYSDKYDDEEFEYRHVMLPKDIAKLVP---------KTHLMFESEWRNLGVQQSQGWVHYMIHEPEPHILLFRR---PLPKKPKK----------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9VHN1-1", "uniprot_id": "Q9VHN1_DROME", "id": "Q9VHN1-1", "name": "Cyclin-dependent kinases regulatory subunit", "aln": "----------------------MPADQIQYSEKYFDDNFEYRHVILPPDLAKHVP---------KAHLMTETEWRNLGVQQSPGWVHYMVHAPEPHVILFRRKRIPAEDAPQVAAANAAQAIANLCG--------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q24152-1", "uniprot_id": "CKS1_DROME", "id": "Q24152-1", "name": "Cyclin-dependent kinases regulatory subunit", "aln": "----------------------MS-KDIYYSDKYYDEQFEYRHVVLPKELVKMVP---------KTHLMTEAEWRSIGVQQSRGWIHYMIHKPEPHILLFRR---PKTD--------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P20486-1", "uniprot_id": "CKS1_YEAST", "id": "P20486-1", "name": "Cyclin-dependent kinases regulatory subunit", "aln": "MYHHYHAFQGRKLTDQERARVLEFQDSIHYSPRYSDDNYEYRHVMLPKAMLKVIPSDYFNSEVGTLRILTEDEWRGLGITQSLGWEHYECHAPEPHILLFKR---PLNYEAELRAATAAAQQQQQQQQQQQQQQQQHQTQSISNDMQVPPQIS", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ..* ** :* *:::*****:** : * :* . ::: * ***.:*: ** ** ** * ****::**:* * ", "identical_positions": 34, "similar_positions": 19, "identity": "22.22%" }, { "cls_id": "homologset.agr.MGI:1889209", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9Z2H7-1", "uniprot_id": "GIPC2_MOUSE", "id": "Q9Z2H7-1", "name": "PDZ domain-containing protein GIPC2", "aln": "MPLGLRGKKKAAKSKEAARLVEGERSSGSQG-VPGPPAPARKLVFHAQLAHGSATGRVEDFSSISELYAKIAGVFEIAPSEILFCTLNTPKIDMGKLLGGQLGLEDFIFAHVKGTKKEVNVYKSEDSLGLTITDNGVGYAFIKRIKDGSTIDSVKTICVGDHIECINGENIVGWRHFEVAKKLKELKKEELFTLQLIEPKKAFEIGPRSKAGKTSTEKIGTSRGTLRLRSKGPATVEELPSEAKAKAIGKVDDLLELYMGIRDIDLATTMFEAGKDKSNPDEFAVALDETLGDFAFPDEFLFDVWGAISDMKQGR-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q498D9-1", "uniprot_id": "GIPC2_RAT", "id": "Q498D9-1", "name": "PDZ domain-containing protein GIPC2", "aln": "MPLGLRGKKKAAKSKETARLVEGERSGGSQG-VPGPPAPARRLVFHAQLAHGSATGRVEDFSSISELYAKIAGVFEIAPSEILFCTLNTPKIDMGKLLGGQLGLEDFIFAHVKGIKKEVNVYKSEDSLGLTITDNGVGYAFIKRIKDGSTIDSVKTICVGDHIECINGENIVGWRHFEVAKKLKELKKEELFTLQLIEPKKAFEIGPRSKAGKTSTEKIGTSRGTLRLRSKGPATVEDLPSEAKAKAIEKVDDLLELYMGIRDIDLATTMFEAGKDKSNPDEFAVALDETLGDFAFPDEFMFDVWGAISDVKQGR-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8TF65-1", "uniprot_id": "GIPC2_HUMAN", "id": "Q8TF65-1", "name": "PDZ domain-containing protein GIPC2", "aln": "MPLKLRGKKK-AKSKETAGLVEGEPTGAGGGSLSASRAPARRLVFHAQLAHGSATGRVEGFSSIQELYAQIAGAFEISPSEILYCTLNTPKIDMERLLGGQLGLEDFIFAHVKGIEKEVNVYKSEDSLGLTITDNGVGYAFIKRIKDGGVIDSVKTICVGDHIESINGENIVGWRHYDVAKKLKELKKEELFTMKLIEPKKAFEIELRSKAGKSSGEKIGCGRATLRLRSKGPATVEEMPSETKAKAIEKIDDVLELYMGIRDIDLATTMFEAGKDKVNPDEFAVALDETLGDFAFPDEFVFDVWGVIGDAKRRGL", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*** ****** *****:* ***** :... * :... ****:*****************.****.****:***.***:*****:********** :****************** :********************************..**************.***********::***************::********** ******:* **** .*.*************::***:***** *:**:*********************** **********************:*****.*.* *: ", "identical_positions": 260, "similar_positions": 37, "identity": "82.28%" }, { "cls_id": "homologset.agr.MGI:1889272", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q6AYP5-1", "uniprot_id": "CADM1_RAT", "id": "Q6AYP5-1", "name": "Cell adhesion molecule 1", "aln": "MASPVLPSGSQCAAAAAVAAAAAPPGLRLRLLLLLLSAAALIPTGDGQNLFTKDVTVIEGEVATISCQVNKSDDSVIQLLNPNRQTIYFRDFRPLKDSRFQLLNFSSSELKVSLTNVSISDEGRYFCQLYTDPPQES-YTTITVLVPPRNLMIDIQ-----KDTAVEGEEIEVNCTAMASKPATTIRWFKGNKELKGKSE-VEEWSD------MYTVTSQLMLKVHKEDDGVPVICQVEHPAVTGNLQTQR---YLEVQYKPQVQ---------------IQMTYPLQGLTREGDAFELTCEATGKPQ------------------PVMVTWVRVDDEMPQHAVLSGPNLFINNLNKTDNGTYR-----CEASNTVGKAHSDYMLYVYDPPTTIPPPT-------TTTTTTTTTTTTTTILTIITDTTATTEPAVHGLTQLPNSAEELDSEDLSDSRAGEEGAIGAVDHAVIGG-VVAVVVFAMLCLLIILGRYFARHKGTYFTHEAKGADDAADADTAIINAEGGQNNSEEKKEYFI-----------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8R5M8-1", "uniprot_id": "CADM1_MOUSE", "id": "Q8R5M8-1", "name": "Cell adhesion molecule 1", "aln": "MASAVLPSGSQCAAAAAVAAAAAPPGLRLRLLLLLLSAAALIPTGDGQNLFTKDVTVIEGEVATISCQVNKSDDSVIQLLNPNRQTIYFRDFRPLKDSRFQLLNFSSSELKVSLTNVSISDEGRYFCQLYTDPPQES-YTTITVLVPPRNLMIDIQ-----KDTAVEGEEIEVNCTAMASKPATTIRWFKGNKELKGKSE-VEEWSD------MYTVTSQLMLKVHKEDDGVPVICQVEHPAVTGNLQTQR---YLEVQYKPQVH---------------IQMTYPLQGLTREGDAFELTCEAIGKPQ------------------PVMVTWVRVDDEMPQHAVLSGPNLFINNLNKTDNGTYR-----CEASNIVGKAHSDYMLYVYDPPTTIPPP---------TTTTTTTTTTTTTILTIITDTTATTEPAVH------------------DSRAGEEGTIGAVDHAVIGG-VVAVVVFAMLCLLIILGRYFARHKGTYFTHEAKGADDAADADTAIINAEGGQNNSEEKKEYFI-----------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9BY67-1", "uniprot_id": "CADM1_HUMAN", "id": "Q9BY67-1", "name": "Cell adhesion molecule 1", "aln": "MASVVLPSGSQCAAAA---AAAAPPGLRLRLLLLLFSAAALIPTGDGQNLFTKDVTVIEGEVATISCQVNKSDDSVIQLLNPNRQTIYFRDFRPLKDSRFQLLNFSSSELKVSLTNVSISDEGRYFCQLYTDPPQES-YTTITVLVPPRNLMIDIQ-----KDTAVEGEEIEVNCTAMASKPATTIRWFKGNTELKGKSE-VEEWSD------MYTVTSQLMLKVHKEDDGVPVICQVEHPAVTGNLQTQR---YLEVQYKPQVH---------------IQMTYPLQGLTREGDALELTCEAIGKPQ------------------PVMVTWVRVDDEMPQHAVLSGPNLFINNLNKTDNGTYR-----CEASNIVGKAHSDYMLYVYDPPTTIPPP---------TTTTTTTTTTTTTILTIITD-----------------------------SRAGEEGSIRAVDHAVIGG-VVAVVVFAMLCLLIILGRYFARHKGTYFTHEAKGADDAADADTAIINAEGGQNNSEEKKEYFI-----------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1NF64-1", "uniprot_id": "A0A8M1NF64_DANRE", "id": "A0A8M1NF64-1", "name": "", "aln": "-----MKQVSNMANTSN--GSLATLLILITISAAIHTGAAQYPVQS-QNLISDNVSVVEGETATISCRVKNNDDSVIQLLNPNRQTIYFKDVRPLKDARFQLVNFSDNELRVSLSNVSLSDEGRYVCQLYTDPPQEA-YADITVLIPPGNPIIESR-----EDIVSEGNETEITCTSMGSKPAATIRWMKGDKELQGKSK-VELTYDK-----MFTVTSWLRLTVTREDDGVPVVCIVDHPAVK-DFQAQK---YLEVQYKPEVQ---------------IVVDFP-SGPIREGENLELTCLAKGKPE------------------PQQVNWVRVDDDVPSHAVITGSDLFIENLNKSYNGTYR-----CVASNPLGEAYDDYILFVRDALTTTPIP---------TTTTTTTISATTSPPDVIQDAAPSTEAAAH------------------DSQAGAE-TQRSMDHALIGG-VVAVVVFAMLCLLIVLGRYFARHKGTYFTHEAKGADDAADADTAIINAEGGHNNSDEKKEYYI-----------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P15278-1", "uniprot_id": "FAS3_DROME", "id": "P15278-1", "name": "Fasciclin-3", "aln": "-----------MSRIVFICLAAILTDALTWAQVNVEPNTALLNEGDRTELLCRYGRSIN------YCRIEIPGEQKVLNLSP--------EWSKTPGFTYFGAGLTAGQCGVSIERVKASNNGQVKCSLGVEGEELSGTIDLVVALRPQQPIIELLSRPNREGYFNEGTEFRARCSVRDGRPPANISWYIDNMPANKRTTPLEVMSSTNDNVELSTSVQEIQWHLSPEDSNRKLVCRSHHQTDRESVPPQEAAYIINVRYAPVHQPDAAVYGLYLEHTAIVNITIRASPQPKIEWTIDGAIVGQGRTDGRYSAYEPQYLGNDEYNVTLAIAGLTLEDTTKIYNLRASNELGLTDYQVRISSSSKPPSSSLDVAAIVGIVVAVAVLVLVVLLIVFARATGRWCFGGKSIKTPTNETSDTESADIKATSTATATTTMGG----------------VGVSAEEEETVNEQESPQEQQQQQQKKAKRLPAFAAAILRRFNEKDSRKYKDNQESLNIVEGSVQEIPATNNAIDGNDNEPKAIVWQSTSPVWTFK", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : : . :* . :*: :: *::: .:. : *.* : . : .:: .: **: .*. *::*: *.* .: : : :.* : * : :*: :. ** * . *: .:*.:.* * .: : :: :* . : * .. : : **.. ::* .* : .. .*. ::*:* * : : : . : :: : . *:.: . : : ::* : : :. :* : : : ..: : .: :* . :* : . . . : .*.*. :: * : * * : : . . : .: : * * .:.. :..: :. : . .: * ::.. :..::: : : ", "identical_positions": 45, "similar_positions": 156, "identity": "8.2%" }, { "cls_id": "homologset.agr.MGI:1889273", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O08589-1", "uniprot_id": "PLM_RAT", "id": "O08589-1", "name": "Phospholemman", "aln": "MASPGHILIVCVCLLSMASAEAPQEPDPFTYDYHTLRIGGLTIAGILFILGILIILSKRCRCKFNQQQRTGEPDEEEGTFRSSIRRLSTRRR", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9Z239-1", "uniprot_id": "PLM_MOUSE", "id": "Q9Z239-1", "name": "Phospholemman", "aln": "MASPGHILALCVCLLSMASAEAPQEPDPFTYDYHTLRIGGLTIAGILFILGILIILSKRCRCKFNQQQRTGEPDEEEGTFRSSIRRLSSRRR", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O00168-1", "uniprot_id": "PLM_HUMAN", "id": "O00168-1", "name": "Phospholemman", "aln": "MASLGHILVFCVGLLTMAKAESPKEHDPFTYDYQSLQIGGLVIAGILFILGILIVLSRRCRCKFNQQQRTGEPDEEEGTFRSSIRRLSTRRR", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A8DZH1-1", "uniprot_id": "A8DZH1_DANRE", "id": "A8DZH1-1", "name": "FXYD domain-containing ion transport regulator", "aln": "MMKSLALVFLTFVPLVLAEGQQTTEDDPFSFDYHRLRVGGLILAAVLCLIGITILLSGHCRCKFNQDKRRRTGSNAQAMLNDTARASEC---", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* . :: . . * :*..: . * ***::**: *::*** :*.:* ::** *:** :*******::* .: :. :..: * . ", "identical_positions": 29, "similar_positions": 33, "identity": "31.52%" }, { "cls_id": "homologset.agr.MGI:1889276", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A096UWG9-1", "uniprot_id": "A0A096UWG9_RAT", "id": "A0A096UWG9-1", "name": "Diacylglycerol kinase", "aln": "MEGDQRSGP--SAQGLLPDGHLILWTLFSVLLPVFITLWCSLQRSRRQLHRRDIFRKSKHCWRDTDLFSHPTYCCVCAQHILQGAFCDCCGLRVDEGCLKKVDKRFPCKEIMLKNDSRAADAMPHHWIRGNVPLCTYCVICRQQCGSQPKLCDYRCVWCQQTVHDECMRGSLKSEKCDFGEFKNLIIPPSYLTSINQMRKDKNTNYEVLASKFGKQWTPLIILANSRSGTNMGEGLLGEFKMLLNPVQVFDVTKTPPIKALQLCTLLPYYSVRVLVCGGDGTVGWVLDAIDEMKIKGQEKYIPEVAVLPLGTGNDLSNTLGWGTGYAGEIPVAQVLRNVMEADGIKLDRWKVQVTNKGYYSLRKPKEFTMNNYFSIGPDALMALNFHAHREKAPSLFSSRILNKAVYLFYGTRDCLVQECKDLNKKIELELDGERVELPNLEGVIVLNIGYWGGGCRLWEGVGDETYPLARHDDGLLEVVGVYGSFHCAQIQVKLANPFRIGQAHTVRLTLKCSRMPMPMQVDGEPWAQGPCTVTITHKTHALMLYFSGEQSDDDLSSPSDHEDLKEAE---------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9R1C6-1", "uniprot_id": "DGKE_MOUSE", "id": "Q9R1C6-1", "name": "Diacylglycerol kinase epsilon", "aln": "MEGDQRSGP--PAQSLLPDGHLVLWTLCSVLLPVFITLWCSLQRSRRQLHRRDIFRKSKHCWRDTDLFSHPTYCCVCAQHILQGAFCDCCGLRVDEGCLKKVDKRFPCKEIMLKND-KAADAMPHHWIRGNVPLCSYCVFCRQQCGSQPKLCDYRCIWCQKTVHDECMRGSLRSEKCDFGEFRNLIIPPSYLTSINQMRKDKNTNYEGLASKFGKQWTPLIILANSRSGTNMGEGLLGEFKILLNPVQVFDVTKTPPIKALQLCTLLPYYSVRVLVCGGDGTVGWVLDAIDEMKIKGQEKYIPEVAVLPLGTGNDLSNTLGWGTGYAGEIPVAQVLRNVMEADGIKLDRWKVQVTNKGYYNLRKPKEFTMNNYFSVGPDALMALNFHAHREKAPSLFSSRILNKAVYLFYGTKDCLVQECKDLNKKIELELDGERVELPNLEGIIVLNIGYWGGGCRLWEGMGDETYPLARHDDGLLEIVGVYGSFHCAQIQVKLANPFRIGQAHTVRLTLKCS--MMPMQVDGEPWAQGPCTVTITHKTHALMLYFSGEQSDDDISSPSDHEDVKEAE---------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P52429-1", "uniprot_id": "DGKE_HUMAN", "id": "P52429-1", "name": "Diacylglycerol kinase epsilon", "aln": "MEAERRPAPGSPSEGLFADGHLILWTLCSVLLPVFITFWCSLQRSRRQLHRRDIFRKSKHGWRDTDLFSQPTYCCVCAQHILQGAFCDCCGLRVDEGCLRKADKRFQCKEIMLKNDTKVLDAMPHHWIRGNVPLCSYCMVCKQQCGCQPKLCDYRCIWCQKTVHDECMKNSLKNEKCDFGEFKNLIIPPSYLTSINQMRKDKKTDYEVLASKLGKQWTPLIILANSRSGTNMGEGLLGEFRILLNPVQVFDVTKTPPIKALQLCTLLPYYSARVLVCGGDGTVGWVLDAVDDMKIKGQEKYIPQVAVLPLGTGNDLSNTLGWGTGYAGEIPVAQVLRNVMEADGIKLDRWKVQVTNKGYYNLRKPKEFTMNNYFSVGPDALMALNFHAHREKAPSLFSSRILNKAVYLFYGTKDCLVQECKDLNKKVELELDGERVALPSLEGIIVLNIGYWGGGCRLWEGMGDETYPLARHDDGLLEVVGVYGSFHCAQIQVKLANPFRIGQAHTVRLILKCS--MMPMQVDGEPWAQGPCTVTITHKTHAMMLYFSGEQTDDDISSTSDQEDIKATE---------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1NVX4-1", "uniprot_id": "A0A8M1NVX4_DANRE", "id": "A0A8M1NVX4-1", "name": "Diacylglycerol kinase", "aln": "ME-ENNEEP-------REEWTLFLWTTFAVLVPVLITLWCSFQRPKRKIQLKDLFRKSKHGWHYTDLFNKPTYCCVCCQPILQGAFCDCCGICSDEQCIQRADRILSCKEIMTQNQ--TDGKFCHQWVKGNVPLASYCGVCKQQCGTQPKLCDYRCVWCQTTVHDDCLS-SLTDDLCDLGEFHSVIIPPCYLYQVNKLRRRHPDEYSKLAAVYGSGWTPVLVLANTRSGNNMGEILLGEFRTLLNPVQVFDLSELPPSKALQLCTLLPPGSVRVLVCGGDGTVGWVLDAIDTMKLKGQDQFIPLVTILPLGTGNDLSNSLGWGAGYAGEIPVEQVLRNVLEAEVVKMDRWKVQVASKGNY-FRKPKVLSMNNYFSVGPDALMALNFHVHREKTPSFFSSRIINKAVYFLYGTKDCLVQECKDLDKRIELELDGEQVTLPNLEGIIVCNIGNWGGGCRLWEGMGDEPYPPTRVDDGLLEVVGVYGSFHCAQIQVKLANPVRLGQAHTVRLVLKSS--RMPMQVDGEPWAQGPCTITITHKTQALMLYHSTEQTDDDDSSASEVEDHIDTSSNAPQTESS", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "** :.. * : *.*** :**:**:**:***:**.:*::: :*:****** *: ****.:*******.* ***********: ** *:::.*: : ***** :*: . . : *:*::*****.:** .*:**** *********:*** ****:*: ** .: **:***:.:****.** .:*::*: : :*. **: *. ***:::***:***.**** *****: *********::: ** ********** *.*****************:* **:***:::** *::***********:****:******** ******:**: :*:*******:.** * :**** ::******:***********.****:**:*****:*****::***:**********:*::*******:* **.***:** *** **********:***.** :* ******:*******************.*:******** **.* ****************:******:*:***.* **:*** **.*: ** :. ", "identical_positions": 377, "similar_positions": 118, "identity": "65.22%" }, { "cls_id": "homologset.agr.MGI:1889277", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q80Z10-1", "uniprot_id": "ASTN2_MOUSE", "id": "Q80Z10-1", "name": "Astrotactin-2", "aln": "MAAAGARRSPGRGLGLRGRPRLGFHPGPPPPPPPPLLLLFLLLLPPPPLLAGATAAAASREPDSPCRLKTVTVSTLPALRESDIGWSGARTGAAAGAGAGTGAGAG--AAAAAASAASPGSAGSAGTAAESRLLLFVRNELPGRIAVQDDLDNTELPFFTLEMSGTAADISLVHWRQQWLENGTLYFHVSMSSSGQLAQATAPTLQEPSEIVEEQMHILHISVMGGLIALLLLLLVFTVALYAQRRWQKRRRIPQKSASTEATHEIHYIPSVLLGPQARESFRSSRLQTHNSVIGVPIRETPILDDYDYEEEEEPPRRANHVSREDEFGSQMTHALDSLGRPGEEKVEFEKKAAAEATQETVESLMQKFKESFRANTPVEIGQLQPASRSSTSAGKRKRRNKSRGGISFGRTKGTSGSEADDETQLTFYTEQYRSRRRSKGLLKSPVNKTALTLIAVSSCILAMVCGNQMSCPLTVKVTLHVPEHFIADGSSFVVSEGSYLDISDWLNPAKLSLYYQINATSPWVRDLCGQRTTDACEQLCDPDTGECSCHEGYAPDPVHRHLCVRSDWGQSEGPWPYTTLERGYDLVTGEQAPEKILRSTFSLGQGLWLPVSKSFVVPPVELSINPLASCKTDVLVTEDPADVREEAMLSTYFETINDLLSSFGPVRDCSRNNGGCTRNFKCVSDRQVDSSGCVCPEELKPMKDGSGCYDHSKGIDCSDGFNGGCEQLCLQQTLPLPYDTTSSTIFMFCGCVEEYKLAPDGKSCLMLSDVCEGPKCLKPDSKFNDTLFGEMLHGYNNRTQHVNQGQVFQMTFRENNFIKDFPQLADGLLVIPLPVEEQCRGVLSEPLPDLQLLTGDIRYDEAMGYPMVQQWRVRSNLYRVKLSTITLSAGFTNVLKILTKESSRDELLSFIQHYGSHYIAEALYGSELTCIIHFPSKKVQQQLWLQYQKETTELGSKKELKSMPFITYLSGLLTAQMLSDDQLISGVEIRCEEKGRCPSTCHLCRRPGKEQLSPTPVLLEINRVVPLYTLIQDNGTKEAFKNALMSSYWCSGKGDVIDDWCRCDLSAFDASGLPNCSPLPQPVLRLSPTVEPSSTVVSLEWVDVQPAIGTKVSDYILQHKKVDEYTDTDLYTGEFLSFADDLLSGLGTSCVAAGRSHGEVPEVSIYSVIFKCLEPDGLYKFTLYAVDTRGRHSELSTVTLRTACPLVDDNKAEEIADKIYNLYNGYTSGKEQQTAYNTLMEVSASMLFRVQHHYNSHYEKFGDFVWRSEDELGPRKAHLILRRLERVSSHCSSLLRSAYIQSRVDTIPYLFCRSEEVRPAGMVWYSILKDTKITCEEKMVSMARNTYGETKGR", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A0G2JYU3-1", "uniprot_id": "A0A0G2JYU3_RAT", "id": "A0A0G2JYU3-1", "name": "Astrotactin-2", "aln": "MAAAGARRSPGPGLGLRGRPRLRFHPGPPPPPPLPLLLLFLLLLPPPPLLAGATAAAASREPDSPCRLKTVTVSTLPALRESDIGWSGARAGAAAGAGAGTGAGAGASAAAAAAAAASPGSAGSAGTAAESRLLLFVRNELPGRIAVQDDLDNTELPFFTLEMSGTAADISLVHWRQQWLENGTLYFHVSMSSSGQLAQATAPTLQEPSEIVEEQLHILHISVMGGLIALLLLLLVFTVALYAQRRWQKRRRIPQKSASTEATHEIHYIPSVLLGPQARESFRSTRLQAHNSVIGVPIRETPILDDYDYEEEEDPPRRANHVSREDEFDSQMTHALDSLGRPGEEKVEFEKK----------------------------------------------------GGISFGRTKGTSGSEADDETQLTFYTEQYRSRRRSKGLLKSPVNKTALTLIAVSSCILAMVCGNQMSCPLTVKVTLHVPEHFIADGSSFVVSEGSYLDISDWLNPAKLSLYYQINATSPWVRDLCGQRTTDACEQLCDPETGECSCHEGYAPDPVHRHLCIRSDWGQSEGPWPYTTLERGYDLVTGEQAPEKILRSTFSLGQGLWLPVSKSFVVPPVELSINPLASCKTDVLVTEDPADVREEAMLSTYFETINDLLSSFGPVRDCSRNNGGCTRNFKCVSDRQVDSSGCVCPEELKPMKDGSGCYDHSKGIDCSDGFNGGCEQLCLQQTMPLPYDATSSTIFMFCGCVEEYKLAPDGKSCLMLSDVCDGPKCLKSDSKFNDTLFGEMLHGYNNRTQHVNQGQVFQMTFRENNFIKDFPQLADGLLVIPLPVEEQCRGVLSEPLPDLQLLTGDIRYDEAMGYPMVQQWRVRSNLYRVKLSTITLSAGFTNVLKILTKESSRDELLSFIQHYGSHYIAEALYGSELTCIIHFPSKKVQQQLWLQYQKETTELGSKKELKSMPFITYLSGLLTAQMLSDDQLISGVEIRCEEKGRCPSTCHLCRRPGKEQLSPTPVLLEINRVVPLYTLIQDNGTKEAFKNALMSSYWCSGKGDVIDDWCRCDLSAFDASGLPNCSPLPQPVLRLSPTVEPSSTVVSLEWIDVQPAIGTKVSDYILQHKKVDEYTDTDLYTGEFLSFADDLLSGLGTSCVAAGRSHGEVPEVSIYSVIFKCLEPDGLYKFTLYAVDTRGRHSELSTVTLRTACPLVDDNKAEEIADKIYNLYNGYTSGKEQQTAYNTLMEVSASMLFRVQHHYNSHYEKFGDFVWRSEDELGPRKAHLILRRLERVSSHCSSLLRSAYIQSRVDTIPYLFCRSEEVRPAGMVWYSILKDTKITCEEKMVSMARNTYGETKGR", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O75129-1", "uniprot_id": "ASTN2_HUMAN", "id": "O75129-1", "name": "Astrotactin-2", "aln": "MAAAGARLSPGPGSGLRGRPRLCFHPGPP--PLLPLLLLFLLLLPPPPLLAGATAAAS-REPDSPCRLKTVTVSTLPALRESDIGWSGARAGAGAGTGAG-----------AAAAAASPGSPGSAGTAAESRLLLFVRNELPGRIAVQDDLDNTELPFFTLEMSGTAADISLVHWRQQWLENGTLYFHVSMSSSGQLAQATAPTLQEPSEIVEEQMHILHISVMGGLIALLLLLLVFTVALYAQRRWQKRRRIPQKSASTEATHEIHYIPSVLLGPQARESFRSSRLQTHNSVIGVPIRETPILDDYDCEEDEEPPRRANHVSREDEFGSQVTHTLDSLGHPGEEKVDFEKKAAAEATQETVESLMQKFKESFRANTPIEIG-QLQPPLRSTSAGKRKRRSKSRGGISFGRAKGTSGSEADDETQLTFYTEQYRSRRRSKGLLKSPVNKTALTLIAVSSCILAMVCGSQMSCPLTVKVTLHVPEHFIADGSSFVVSEGSYLDISDWLNPAKLSLYYQINATSPWVRDLCGQRTTDACEQLCDPETGECSCHEGYAPDPVHRHLCVRSDWGQSEGPWPYTTLERGYDLVTGEQAPEKILRSTFSLGQGLWLPVSKSFVVPPVELSINPLASCKTDVLVTEDPADVREEAMLSTYFETINDLLSSFGPVRDCSRNNGGCTRNFKCVSDRQVDSSGCVCPEELKPMKDGSGCYDHSKGIDCSDGFNGGCEQLCLQQTLPLPYDATSSTIFMFCGCVEEYKLAPDGKSCLMLSDVCEGPKCLKPDSKFNDTLFGEMLHGYNNRTQHVNQGQVFQMTFRENNFIKDFPQLADGLLVIPLPVEEQCRGVLSEPLPDLQLLTGDIRYDEAMGYPMVQQWRVRSNLYRVKLSTITLAAGFTNVLKILTKESSREELLSFIQHYGSHYIAEALYGSELTCIIHFPSKKVQQQLWLQYQKETTELGSKKELKSMPFITYLSGLLTAQMLSDDQLISGVEIRCEEKGRCPSTCHLCRRPGKEQLSPTPVLLEINRVVPLYTLIQDNGTKEAFKSALMSSYWCSGKGDVIDDWCRCDLSAFDANGLPNCSPLLQPVLRLSPTVEPSSTVVSLEWVDVQPAIGTKVSDYILQHKKVDEYTDTDLYTGEFLSFADDLLSGLGTSCVAAGRSHGEVPEVSIYSVIFKCLEPDGLYKFTLYAVDTRGRHSELSTVTLRTACPLVDDNKAEEIADKIYNLYNGYTSGKEQQMAYNTLMEVSASMLFRVQHHYNSHYEKFGDFVWRSEDELGPRKAHLILRRLERVSSHCSSLLRSAYIQSRVETVPYLFCRSEEVRPAGMVWYSILKDTKITCEEKMVSMARNTYGESKGR", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "******* *** * ******** ****** * ***********************: *******************************:**.**:*** ***:******.*********************************************************************************************:********************************************************************:***:******************* **:*:**************.**:**:*****:******:**** *******:*******************************************************.***************************************************************************:********************:*************************************************************************************************************************************************************************:*****:*******************************:******.************************************************************************************************************:****************:****************************************************************************************************************************************.****************************.******** *********************:*********************************************************************************************************************************** **********************************************************************:*:******************************************:***", "identical_positions": 1247, "similar_positions": 32, "identity": "92.1%" }, { "cls_id": "homologset.agr.MGI:1889278", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "M0R6Q9-1", "uniprot_id": "M0R6Q9_RAT", "id": "M0R6Q9-1", "name": "All trans-polyprenyl-diphosphate synthase PDSS1", "aln": "MASGLAGTGTRFLHALSRVGQQFGRTFLAKSGRRYWPEPVAPRRVRDDPRPLGGPGRTGCGLALPVPSFRLRVWAWGRGGATAGRDFQTRTMALRWSCWRRRCSWRPALVGSPRPARPGCAGPLGTRAASDTRA-----------QIPYFSLLKILTSASPNMHSISQFHQRTPAMCCCSQTQS--GEKYSDPFKLGWRDLKGLYEDIRKELHISTR--------ELKDMSEYYFDGKGKAFRPIIVVLMARACNIHHNN-SREMQARQRSVALVAEMIHTATLVHDDVIDDASSRRGKHTVNKVWGEQKAVLAGDLILSAASIALARIGNTAVVSLLAQVIEDLVRGEFLQLGSKENENER--------------------------------------------FAHYLEKTFKKTASLIANSCKAVSVLGCPDPVVHEIAYQYGKNVGIAFQLIDDVLDFTSCSDQMGKPTSADLKLGIATGPVLFACQQFPEMNAMIMRRFSLPGDVDRARQYVLQSDGVQQTTYLAQQYCHKAVR-EIRKLRPSTERDALIQLSESVLTRDK", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q33DR2-1", "uniprot_id": "DPS1_MOUSE", "id": "Q33DR2-1", "name": "All trans-polyprenyl-diphosphate synthase PDSS1", "aln": "-------------------------------------------------------------------------------------------MAMRWSCWRRGCSWRPTAVGSPRRERPGCVEPLGTRAASDTRA-----------QIPYFSLMKILMSASPTMHSISQFHQRTPAMCSCRQTQS--GEKYSDPFKLGWRDLKGLYEDIRKELHISTR--------ELKDMSEYYFDGKGKAFRPIIVVLMARACNIHHNN-AREMQASQRSIALVAEMIHTATLVHDDVIDDASSRRGKHTVNKIWGEKKAVLAGDLILSAASVALARIGNTAVVSMLAQVIEDLVRGEFLQLGSKENENER--------------------------------------------FAHYLEKTFKKTASLIANSCKAVSVLGCPDPVVHEIAYQYGKNVGIAFQLIDDVLDFTSCSDQMGKPTSADLKLGIATGPVLFACQQFPEMNAMIMRRFSLPGDVDRARQYVLQSDGVQQTTYLAQQYCHKAVR-EIRKLRPSTERDALIQLSESVLTRDK", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q5T2R2-1", "uniprot_id": "DPS1_HUMAN", "id": "Q5T2R2-1", "name": "All trans-polyprenyl-diphosphate synthase PDSS1", "aln": "-------------------------------------------------------------------------------------------MASRWWRWRRGCSWKPAAR-SPGPGSPGRAGPLGPSAAAEVRAQVHRRKGLDLSQIPYINLVKHLTSACPNVCRISRFHHTTPD----SKTHS--GEKYTDPFKLGWRDLKGLYEDIRKELLISTS--------ELKEMSEYYFDGKGKAFRPIIVALMARACNIHHNN-SRHVQASQRAIALIAEMIHTASLVHDDVIDDASSRRGKHTVNKIWGEKKAVLAGDLILSAASIALARIGNTTVISILTQVIEDLVRGEFLQLGSKENENER--------------------------------------------FAHYLEKTFKKTASLIANSCKAVSVLGCPDPVVHEIAYQYGKNVGIAFQLIDDVLDFTSCSDQMGKPTSADLKLGLATGPVLFACQQFPEMNAMIMRRFSLPGDVDRARQYVLQSDGVQQTTYLAQQYCHEAIR-EISKLRPSPERDALIQLSEIVLTRDK", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9V9Z3-1", "uniprot_id": "Q9V9Z3_DROME", "id": "Q9V9Z3-1", "name": "All trans-polyprenyl-diphosphate synthase PDSS1", "aln": "----------------------------------------------------------------------MACLSTSGRVVCGSRRQQAHKLLYQLFGSRPGYTAPSAATGLFSPPKVQQQAMRLYHGLSFSMG----------KDYPDLLQSPHKCSQSLQYSQSSKANLRQHSSVHTQQPAGPVREFQIDPYIILDDDLKYFYDDVRYLLKSGTSQP------ELDTIASYYFDGQGKALRPMVTMLMAKAINYHLNNESHQLVHKQRQIALFSEMVHSASLVHDDVIDQSDFRRGKPSVNALWNHKKVTMAGDYILSIASIMIARLRSDDVTIVLSQILTDLVQGEFMQLGSRETENER--------------------------------------------FAHYLTKTYRKTASLIANALKATAVIAQADDNVAEVAFQYGRNIGLAFQLVDDMLDFVSSTEQMGKPTAADLKLGLATAPVLFACEKYPELNPMVMRRFSEPGDVERAFELVHKSHGLEQTRFLAKKHCNEAIR-LAQELTESPYQKGLQVVADLVINRMK", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P18900-1", "uniprot_id": "COQ1_YEAST", "id": "P18900-1", "name": "Hexaprenyl pyrophosphate synthase, mitochondrial", "aln": "-----------------------------------------------------------------------------------MFQRSGAAHHIKLISSRRCRFKSSFAVALNAASKLVTPKILWNNPISLVSK---------EMNTLAKNIVALIGSGHPVLNKVTSYYFETEGKKVRPLLVLLLSRALSEIPMTERNHLKIDKSDVPEDPIYSKPSQNQLFQRPASSISPLHILHGIKPLNPLTKGPEPLPEETFDKQ--RGILPKQRRLAEIVEMIHTASLLHDDVIDHSDTRRGRPSGNAAFTNKMAVLAGDFLLGRATVSISRLHNPEVVELMSNSIANLVEGEFMQLKNTSIDADIDTIENGHKLLPVPSKKLEVKEHDFRVPSRQQGLQLSHDQIIETAFEYYIHKTYLKTAALISKSCRCAAILSGASPAVIDECYDFGRNLGICFQLVDDMLDFTVSGKDLGKPSGADLKLGIATAPVLFAWKEDPSLGPLISRNFSERGDVEKTIDSVRLHNGIAKTKILAEEYRDKALQNLRDSLPESDARSALEFLTNSILTRRK", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : * . : : * : . : .** .*: .. . :: :: *.:.*: . . : . :: : : ** :* . **:*:*:*:******.:. ***: : * : .: ..:*** :*. *:: ::*: . * :::: : :**.***:** . . : : * :*: **: ***:**::: :..:::. .. * : .:::*:*:*:.***:**:***. . .::***:.******:**.***** :: *.:..:: *.** ***::: : * .*: :* **::: .:*:: .* * :..* ::: ::.* *", "identical_positions": 94, "similar_positions": 135, "identity": "16.58%" }, { "cls_id": "homologset.agr.MGI:1889286", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3Z9H1-1", "uniprot_id": "D3Z9H1_RAT", "id": "D3Z9H1-1", "name": "", "aln": "-MGTK-------WHSPKLSLALVFLTLEAGWAQEGSEPVLLEGECLVVCEPGRPTAGGPGGAALGEAPPGRVAFAAVRSHHHEPAGETGNSTSGAIYFDQVLVNEGGGFDRPSGCFVAPVRGVYSFRFHVVKVYNRQTVQVSLMLNTWPVISAFANDPDVTREAATSSVLLPLDPGDRVSLRLRRGNLLGGWKYSSFSGFLIFPL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9JHG0-1", "uniprot_id": "CBLN3_MOUSE", "id": "Q9JHG0-1", "name": "Cerebellin-3", "aln": "-MGTE-------WHKPKLSLALVLLTLEAGWAQEGSEPVLLEGECLVVCEPGRPTAGGPGGAALGEAPPGRVAFAAVRSHHHEPAGETGNGTSGAIYFDQVLVNEGEGFDRTSGCFVAPVRGVYSFRFHVVKVYNRQTVQVSLMLNTWPVISAFANDPDVTREAATSSVLLPLDPGDRVSLRLRRGNLLGGWKYSSFSGFLIFPL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6UW01-1", "uniprot_id": "CBLN3_HUMAN", "id": "Q6UW01-1", "name": "Cerebellin-3", "aln": "MLGAKPHWLPGPLHSPGLPLVLVLLALGAGWAQEGSEPVLLEGECLVVCEPGRAAAGGPGGAALGEAPPGRVAFAAVRSHHHEPAGETGNGTSGAIYFDQVLVNEGGGFDRASGSFVAPVRGVYSFRFHVVKVYNRQTVQVSLMLNTWPVISAFANDPDVTREAATSSVLLPLDPGDRVSLRLRRGNLLGGWKYSSFSGFLIFPL", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :*:: *.* *.*.**:*:* *************************.:***********************************.*************** ****.**.******************************************************************************************", "identical_positions": 180, "similar_positions": 13, "identity": "87.8%" }, { "cls_id": "homologset.agr.MGI:1889294", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q62176-1", "uniprot_id": "RBM38_MOUSE", "id": "Q62176-1", "name": "RNA-binding protein 38", "aln": "MLLQPA-CSPSV-FPRPSAAPSAMHGSQKDTTFTKIFVGGLPYHTTDASLRKYFEGFGDIEEAVVITDRQTGKSRGYGFVTMADRAAADRACKDPNPIIDGRKANVNLAYLGAKPRSLQTGFAVGVQQLHPTLIQRTYGLTPHYIYPPAIVQPSVVIPATPVPSLSSPYLEYTPASPAYAQYPPATYDQYPYAASPAAATSFVGYGYPAAVPQALSAAAPAGTTFVQYQAPQLQPDRMQ", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D3ZGE9-1", "uniprot_id": "D3ZGE9_RAT", "id": "D3ZGE9-1", "name": "RNA-binding protein 38", "aln": "MLLQPA-CAPSV-FPRPSAAPSAMHGSQKDTTFTKIFVGGLPYHTTDASLRKYFEGFGDIEEAVVITDRQTGKSRGYGFVTMADRAAADRACKDPNPIIDGRKANVNLAYLGAKPRSLQTGFAVGVQQLHPTLIQRTYGLTPHYIYPPAIVQPSVVIPATPVPSLSSPYLEYTPASPAYAQYPPATYDQYPYAASPATATSFVGYGYPAAIPPALSATAPAGTTFVQYQAPQLQPDRMQ", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9H0Z9-1", "uniprot_id": "RBM38_HUMAN", "id": "Q9H0Z9-1", "name": "RNA-binding protein 38", "aln": "MLLQPAPCAPSAGFPRPLAAPGAMHGSQKDTTFTKIFVGGLPYHTTDASLRKYFEGFGDIEEAVVITDRQTGKSRGYGFVTMADRAAAERACKDPNPIIDGRKANVNLAYLGAKPRSLQTGFAIGVQQLHPTLIQRTYGLTPHYIYPPAIVQPSVVIPAAPVPSLSSPYIEYTPASPAYAQYPPATYDQYPYAASPATAASFVGYSYPAAVPQALSAAAPAGTTFVQYQAPQLQPDRMQ", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "****** *:**. **** ***.******************************************************************:**********************************:***********************************:*********:***************************:*:*****.****:* ****:*********************", "identical_positions": 223, "similar_positions": 12, "identity": "93.31%" }, { "cls_id": "homologset.agr.MGI:1889295", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q5EBA0-1", "uniprot_id": "ERAL1_RAT", "id": "Q5EBA0-1", "name": "GTPase Era, mitochondrial", "aln": "MAAPRRYFPGIVRALLGAWQVGSHAGREWVSPPGSLLGNHVRCVSCVVGATFSGPLLASASSRYGQDSALDRILG-FPQPDSSLVPCVPAVSVHRDEQNLLLVHTPDMPENPRVLRVVLLGAPNAGKSTLSNQLLGRKVFPVSKKVHTTRCQALGVITEKETQVILLDTPGIISPVKQKRHHLELSLLEDPWKSMESADLVVVLVDVSDKWTRSRLSPQVLQCLTKFSQVPSILVLNKVDCLKQKSVLLELTAALTEGVVNGKMLNVRQAFR------------SRPSTHCPGPETEDPNTHAVRSPQRTG-WPYFQEIFMLSALNNKDVNTLKQYLLTQAQPGPWEFHSGVLTSQTPEEICANKIREKLLEYLPEEVPYSVQQKTVIWEEGPSGELVIQQNLLVPKESHVRILIGQKGLLISQIAQEVSQDLMDIFLCDVLLRLSVKLLK-----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9CZU4-1", "uniprot_id": "ERAL1_MOUSE", "id": "Q9CZU4-1", "name": "GTPase Era, mitochondrial", "aln": "MAAPRRYCAGLVRALLGARQVGSHAGREWLAPPGCLLGNQARCVSCVVGSTFSGPLLASASSRYGQDSALDRILG-FSQPDSSLVPSVPAVSVHRDEQNLLLVHTPDMPENPRVLRVVLLGAPNAGKSTLSNQLLGRKVFPVSKKVHTTRCQALGVITEKETQVILLDTPGIISPVKQKRHHLERSLLEDPWTSMESADLVVVLVDVSDKWTRSRLNPQVLQCLTKFSQVPSILVLNKVDCLKQKSVLLELTAALTEGVVNGKKLNIKQALR------------SRSSTHCPGPETEGPNAHSVRNPQRIG-WPYFQEIFMLSALNNKDVNTLKQYLLTQAQPGPWEFHSGVLTSQTPEEICANKIREKLLEYLPEEVPYGVQQKTVIWEEGPSGELVIQQNLLVPKESHVRILIGQKGLLISQIAQEVGRDLMDIFHCDVLIRLSVKLLK-----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O75616-1", "uniprot_id": "ERAL1_HUMAN", "id": "O75616-1", "name": "GTPase Era, mitochondrial", "aln": "MAAPSWRGARLVQSVLRVWQVGPHVARERVIPFSSLLGFQRRCVSCVAGSAFSGPRLASASRSNGQGSALDHFLG-FSQPDSSVTPCVPAVSMNRDEQDVLLVHHPDMPENSRVLRVVLLGAPNAGKSTLSNQLLGRKVFPVSRKVHTTRCQALGVITEKETQVILLDTPGIISPGKQKRHHLELSLLEDPWKSMESADLVVVLVDVSDKWTRNQLSPQLLRCLTKYSQIPSVLVMNKVDCLKQKSVLLELTAALTEGVVNGKKLKMRQAFH------------SHPGTHCPSPAVKDPNTQSVGNPQRIG-WPHFKEIFMLSALSQEDVKTLKQYLLTQAQPGPWEYHSAVLTSQTPEEICANIIREKLLEHLPQEVPYNVQQKTAVWEEGPGGELVIQQKLLVPKESYVKLLIGPKGHVISQIAQEAGHDLMDIFLCDVDIRLSVKLLK-----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "B0S6U7-1", "uniprot_id": "ERAL1_DANRE", "id": "B0S6U7-1", "name": "GTPase Era, mitochondrial", "aln": "-MTLRSCETFLRRSLRFSTALNLTAFPEHEQLY---LRVSSGCSVFRPQTVRKCLFHWTPACTVSQGVFLDRLQKGAAVTDESLCNQPVSVSPDRAQQFSLLMKDPDQPENAKSLKVAIVGSPNAGKSTLTNQLLGRKLFAVSSKVHTTRSRAVGVLTENDTQIVLLDTPGLTTQIKAKRHQLENSLLVDPFKSLKEADLVVVLVDVSDKWTRSKLSYEVLKCLALNPDVPAVLVLNKVDLLKNKALLLDITAQLTEGMVNGKKIRIHGASKPVRKAAAGANSRLKEKKAAGSLEDEADHEDKLKALKSHGGWPHFKDVFMLSSIDHEDVETLKRYLFVAAKPCQWQYHSEVLTDQSPEDVCFNTIREKLLQNLPKEVPYTMTQEIEVWKESEDGVLDISIKLYVQKETHMKMVIGPGGQLITRINQEAGNDLMKIFLCNVRLKISVKLRK-----", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VG07-1", "uniprot_id": "Q9VG07_DROME", "id": "Q9VG07-1", "name": "GTPase Era, mitochondrial", "aln": "---------------------------------------------MRYNLLASSLKLLNSTKTHNLFLVNVRSLTGAAHTNDAVAPTTRPPPAE----------SRNPGEEQRSLHIAVIGVPNVGKSTFINNTVNHRVCPTSAKVHTTRQSNTAIYTTGQTQLVFYDTPGLVTQHEIRRHHLDQNFKSAYRHAIQHADIIAVVHDASNAWTRKELHPTVLDTLKAYSNLPSFLVLNKIDALKSKRLLLDLIKTLTNDTLTVGKR---------------------------EVQAKSALAKEIRINKRESSWSHFSDVFLVSALTGNGLQEMQNYLVGQAKPRDWKYPADIHTDSSPEALIVESVRARLLDYLPQEIPYNLKCEIEYYSVEKN-VVYTSVQVQCPTTRIERLICGEGNGKLRQITERVTSDLVEMFGQAVSLTISTVSKGKKTAA", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . ..: . : . .:.:: . . . : *: : *::.::* **.****: *: :.::: ..* ****** .: * :**::: ****: : : :**:*: .: ::: **::.*: *.*: ***..* :* * .::*:.**:**:* **.* :**:: **:. :. : . : : . *.:*.::*::*:: :.:: ::.**. *:* *:: : : *..:** : : :* :**: **:*:** : : :. . : . :: . ::: * . : :* :.. **:.:* * : :*. ", "identical_positions": 78, "similar_positions": 136, "identity": "17.11%" }, { "cls_id": "homologset.agr.MGI:1889334", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A0G2JY61-1", "uniprot_id": "A0A0G2JY61_RAT", "id": "A0A0G2JY61-1", "name": "", "aln": "------------------------------------------------------------------------------MPLR---------------------DKYCQTDHHHHGCCE------------PVYILEPGDPPLLQQPVQTSKSGIQQIIECFRSGTKQLKHILLKDVDTIFECKLCRSLFRGLPNLITHKKFYCPPSLQMDDNLPDVNDKQSQAIS----DLLEAIYPRVDKREYIIKLEPIETNQN------------AVFQYISR---TDNPAEVTESSSTPEQT-EVQIQETSSEQPKAVP---EADTEVEEAIEPPPVETVADEATAPTEEQPQESQADLETSDSSDLGHQLI-CCLCRKEFNSRRGVRRHIRKVHKKKMEELKKYIETRKTPN-QSSKGRSKSALVSLS---RSCPVCCKSFATKANVRR--HFDEVHRGLRRDSITPDIATKPGQPLFLDSAS-PKKSFKTRKQKSS--KAEYNLTACKCLLCKRKYSSQIMLKRHMQIVHKITLSGANSKR--------EKGPNNTANSSEVKVKVEPGDSVESSPPSITHSPQNELKGTNHSNEKKNTPATQKNKVKQDSESPKSASPSAAGGQQKTRKPKLSAGFDFKQLYCKLCKRQFTSKQNLTKHI-ELHTDGNN-IYVKFYKCPLCTYETRRKRDVIRHITVVHKKS------------------------------------------------------------SRYLGKITASLEIRAIKK-----PIDFVLNKVAKRGPSRDEAKHNDSKHDGTSN----------------------------SPSKKYEVADVG---------------------------------------------------------IEVKVTKNFSLHRCNKCG--------------------------------------------KAFAKKTYLEHHKKTHKANATTSPEGNKTKGRSTRSKALVCLAKPSPRSAAILRPPAGAVTTRQAASSCRAKLRGAARERQHAARALGRSAAP------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q0VEE6-1", "uniprot_id": "ZN800_MOUSE", "id": "Q0VEE6-1", "name": "Zinc finger protein 800", "aln": "------------------------------------------------------------------------------MPLR---------------------DKYCQTDHHHHGCCE------------PVYILEPGDPPLLQQPVQTSKSGIQQIIECFRSGTKQLKHILLKDVDTIFECKLCRSLFRGLPNLITHKKFYCPPSLQMDDNLPDVNDKQSQAIS----DLLEAIYPRVDKREYIIKLEPIETNQN------------AVFQYISR---TDNPAEVTESSSTPEQT-EVQIQETSSEQLKAVP---DADTEVEEAIEPPSIETVVDEAAAPTEEQPQESQADLETSDSSDLGHQLI-CCLCRKEFNSRRGVRRHIRKVHKKKMEELKKYIETRKTPN-QSSKGRSKSVLVSLS---RSCPVCCKSFATKANVRR--HFDEVHRGLRRDSITPDIATKPGQPLFLDSAS-PKKSFKTRKQKSS--KAEYNLTACKCLLCKRKYSSQIMLKRHMQIVHKITLSGANSKR--------EKGPNNTANSS--EVKVELADSVESSPPSITHSPQNELKGTNHSNEKKNTPATQKNKVKQDSESPKSASPSAAGGQQKTRKPKLSAGFDFKQLYCKLCKRQFTSKQNLTKHI-ELHTDGNN-IYVKFYKCPLCTYETRRKRDVIRHITVVHKKS------------------------------------------------------------SRYLGKITASLEIRAIKK-----PIDFVLNKVAKRGPSREEAKHNDSKQDGTSN----------------------------SPSKKYEVADVG---------------------------------------------------------IEVKVTKNFSLHRCNKCG--------------------------------------------KAFAKKTYLEHHKKTHKANATNSPEGNKTKGRSTRSKALV-----------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q2TB10-1", "uniprot_id": "ZN800_HUMAN", "id": "Q2TB10-1", "name": "Zinc finger protein 800", "aln": "------------------------------------------------------------------------------MPLR---------------------DKYCQTDHHHHGCCE------------PVYILEPGDPPLLQQPLQTSKSGIQQIIECFRSGTKQLKHILLKDVDTIFECKLCRSLFRGLPNLITHKKFYCPPSLQMDDNLPDVNDKQSQAIN----DLLEAIYPSVDKREYIIKLEPIETNQN------------AVFQYISR---TDNPIEVTESSSTPEQT-EVQIQETSTEQSKTVP---VTDTEVET-VEPPPVEIVTDEVAPTSDEQPQESQADLETSDNSDFGHQLI-CCLCRKEFNSRRGVRRHIRKVHKKKMEELKKYIETRKNPN-QSSKGRSKNVLVPLS---RSCPVCCKSFATKANVRR--HFDEVHRGLRRDSITPDIATKPGQPLFLDSIS-PKKSFKTRKQKSSS-KAEYNLTACKCLLCKRKYSSQIMLKRHMQIVHKITLSGTNSKR--------EKGPNNTANSSEIKVKVEPADSVESSPPSITHSPQNELKGTNHSNEKKNTPAAQKNKVKQDSESPKSTSPSAAGGQQKTRKPKLSAGFDFKQLYCKLCKRQFTSKQNLTKHI-ELHTDGNN-IYVKFYKCPLCTYETRRKRDVIRHITVVHKKS------------------------------------------------------------SRYLGKITASLEIRAIKK-----PIDFVLNKVAKRGPSRDEAKHSDSKHDGTSN----------------------------SPSKKYEVADVG---------------------------------------------------------IEVKVTKNFSLHRCNKCG--------------------------------------------KAFAKKTYLEHHKKTHKANASNSPEGNKTKGRSTRSKALV-----------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AC58IVT2-1", "uniprot_id": "A0AC58IVT2_DANRE", "id": "A0AC58IVT2-1", "name": "", "aln": "MMYVRHCSVSLLNASFNDKRYISRVLLQSFNRIWHRSCVCYFKLLFFRSRGQMSAMLLGAYRWSIHDVLGCFGCSRTLIPFRFIKGASEMEATKSEVQGSLTSDKYCQTETLQACCCQTTETPQEPCGKNPVHLIEPGDPPLLQQQLQTSKSGIHQIIECFRSGTAQLKQMLLKEVDTIFECKICRSLFRGLPNLVTHKELYCFSQQPQSDDP--SKGGQSHAIK----ELLQAIYPQKEQEKQTIQLEAIETNPN------------AVFQHVSLGEIQDMPESPAPTTTAPAPVPEILLPEKKNRRKSILAPKKVQQSDFEDEMETEVEEQPANEGPSCDEQMKIEGEEEEEESAASEVKELRISCCLCGKDFGSRRSVRRHCRKMHWQRMEELRKFTETRTVPISLLSVVKDKHPVEPPPSPGKSCPVCKKSFATKANVRR--HFDEVHRGLKRDLITPDIATRPGQPLLLDTPS-PPSPAKVPSSPLKQEKPQYNLTSCRCKLCKRKYSSQLMLRRHMRIVHKI--------------------------------------------PTLENSSQ-----------KSKSKQERRDKVYVKKESLSKAS--EDDGNQ-------SVSFDFKRIYCWLCKRQFSTSYNLGKHIAELHTDGNDSIYIKFYRCPICRYESRRKRDVIRHITVVHKKS------------------------------------------------------------SRYLAKVMPALENQAVKK-----PADAILSSASKKINAKEDGSGKHKTQDPPASPSSRQQDLL------------------VSPKAKKQESQTSPNTRKHSALTSLNTGKLESPLAPNRQDKNLQAAKNPHVTRSHNVIKGPPITRSQETCTEVRVTKNFSLHACDMCG--------------------------------------------RAFAKKVYLETHRRRHKTAIAS---GDKLQGRSTRSKALI-----------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VNI5-1", "uniprot_id": "Q9VNI5_DROME", "id": "Q9VNI5-1", "name": "C2H2-type domain-containing protein", "aln": "------------------------------------------------------------------------------MRKR---------------------SSRCNSDTFKEEQMD----------------HNGDDISLLQRPLRTAHTGFEEARRAYEDGTSEVRQLLSLECSLIYECKVCRNMFRSLANFISHKRVFCCVSARSANGSGYTDQNSTMIIQTGGGPSPQDIEHMLRSRSTGCSPVPRDVRPLRGGGGGGIRDLSGVIERLRREKATSQAKCSSPTVLQLESVPNSSQAVYQTIKVDHDDSIRTELDEVHRMLNPSETIVGPDGKALATVKLENNAGSDSGEQSISDETEPSIFCEICNLTFQTHKTLEVHIQKHHSSSAFVFQCPACSLTFLQAAAVIRHLSKDHKKPT---RRIRMMRNTILKRRIQQGDVQPKGPCRELKRLQLSDDVVGYVPEPLDASGEHRKIMSLCIYCEKSFERRAALSTHLLNCRAKQEALAKPAPSVKKLKMKSNDSSVDAADEDPTTSIDLPKKKPIKTEEITLNEMFADLPEPNDSFAPGLHTVSLDQLNLGNVSDSASDEASNTDDEHELTPGAGPESNADAEDVKGKAKKKRNVPVEKQLRCRCKICHKQFNALGNLRRHISMFHYRARR------FGCNLCEYRAFRRYDIVNHLGFTHKIEGDRDQLTEQYVSTHECEYSRDDVDGDIILLDKEEELTVMEKDAKPPIKTYERRLKHLKTLTESVGEVQPKSPTAAIKEEPGQEPLEGTPTPSKKRRKSRTQISPESGEHSQEKRPIRKRVKAVNKDFVYDLVSFKPDGSCQQPPGAQAVESMRAKLRRPAPVGNDESKAKQYEAYITEEKKHLVFGITRRIMLELVSQGLAVSATLPELPSERPQIRPRLISHSRSESGSQQKQNIVETTVDPAPETESFIEKIAKRTAAAGKDNAVISNLWNKVNTAIAQQEKQQKKEQEPLQEAQPEEKSETEKSKSPLQAPSPPSPPSICEATVPETLATTGMDCLRGKGSQAGASTVFPSLPKPPSVLQAAANGTIQFTLDSLLRAALQN", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : * .. *::: : : : .* .***: ::*:::*:.: ..:..** :::::* : . *:***:**.:**.*.*:::**..:* . :. . .: *. : * ... . . :.. .*:: : . . : : . : .. : . :.. ::. : . : :. : . *: . * * :* * ::: :. * :* * . :: : . : . . : : ::: .: : : . * *:* :: *:. :** . . . :. . .* :. :. ::::: : * : . .. :: : .:. . : . : * :*::**.: ** :** :* .. : * :* *.: *: *::.*: ..** . :. :.:: . *:*: * : . *: :: : . . :. .* : : . . :: .: * . .* :. : . * ::: .: :* : ..::* ", "identical_positions": 70, "similar_positions": 217, "identity": "6.46%" }, { "cls_id": "homologset.agr.MGI:1889336", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q6NSR3-1", "uniprot_id": "ADCK2_MOUSE", "id": "Q6NSR3-1", "name": "Uncharacterized aarF domain-containing protein kinase 2", "aln": "-------MVTPWRLSVRVCLSHLRCFEFRKELG------HSRPLGCSRNARLCWFLLGTLPKLISAHGSVGEGAPGSLCQRKTHWSDLAENGLVEKVAQEG------PLARVLLCLRLGLRAGVLLAKFFPLLFLYPLTYLAPGLST------------LWLHLLFKATETSGPTYIKLGQWASTRRDLFSEAFCTQFSKLHVQVTPHPWARTEYLLQQAFGEDWGSLLFFET-REPVGSGCVAQVYKAFASISLLEEDRIWRLGELSAPG----TRAVVMQREPF---MKDRKPSENLADEAFLEKLLLPKADLGGSEVGVS--QAPWHLPKSDHLIPVAVKVLHPGLLSQVSMDLLLMKIGSKALGLLPGVKWLSLPEIVEEFEKLMVQQTDLRYEAQNLEHFQHNFQDMASVKFPTPLRPLITRDILVETYEESVPVSSYQQAG---IPTDLKRKIAQLGINMLLKMIFVDNFVHGDLHPGNILVQGADG-------VSPSLEMQQQQVNVCDTLVATIAP----------ALCPLRLVLLDAGIVAKLQASDLRNFRAVFQAVVMGQGHRVAELMLHHAQ-ANECRDVERFKAEMATLVTQARKNIVTLEKLHVSSLLSSVFKLLMTHKVKLESNFASIVVAIMVLEGLGRSLDPTLDILEAAKPFLFKG-----PASFL-----------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D3ZRE6-1", "uniprot_id": "D3ZRE6_RAT", "id": "D3ZRE6-1", "name": "", "aln": "-------MVNPWRLSVRVCLSHLRCFEFGKELG------LSRPLGCSRNARLCWFLLGALPKFISAQGSVGEAAPGSLCQRKTHWSNLPENGLVK-VAQEG------PLARILLCLCLGLRAGVLLAKFLPLLFLYPLTYLAPGFST------------LWLHLLFKATETSGPTYIKLGQWASTRRDLFSEAFCVQFSKLHVQVTPHPWARTEYLLQQAFGEDWHSILFFET-QEPVGSGCVAQVYKAFANISLLEKGRIWRLGELSVPG----TGTVGTQRDPF---MKDWRPSENLADETFIEKLLLPKADLVRSEVGVS--QAPGQPPKSDHLIPVAVKVLHPGLLSQVYIDLLLMKIGSQALGLIPGVKWLSLPEIVEEFEKLMVQQTDLRYEAQNLEHFQHNFQNMASVKFPTPLHPLITRDILVETYEESVPVSSYQQAG---VPTDLKRKIAQLGINMLFKMIFVDNFVHGDLHPGNILVQGADG-------VSSSLEMQQQQVDVYDTLVATIAP----------ALCPLRLVLLDAGIVAKLQASDLRNFRAVFLAVAMGQGHRVAELMLHHAQ-ANECKDVEKFKAEMATLVTQARKNTLTLEKLHVSSLLSSVFKLLMTHKVKLESNFASIVVAIMVLEGLGRSLDPKLDILEAAKPFLLKG-----PASFL-----------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q7Z695-1", "uniprot_id": "ADCK2_HUMAN", "id": "Q7Z695-1", "name": "Uncharacterized aarF domain-containing protein kinase 2", "aln": "-------MVAPWRVSVRVCLSHLRCFELRQGLS------LLRPSECPRDARLCWLLLGTLPKVVSLCGDVGEGAPDVLSRRRVRCSGAAGAGPAESLPRAG------PLGGVFLHLRLWLRAGALLVKFFPLLLLYPLTYLAPSVST------------LWLHLLLKATETSGPTYIKLGQWASTRRDLFSEAFCAQFSKLHVRVTPHPWTHTERFLRQAFGDDWGSILSFEN-REPVGSGCVAQVYKAYANTAFLETDSVQRLGRASCLPPFSHTGAVGGLRELFGYLGNGRKPPENLADQSFLERLLLPKADLVGSNAGVSRAQVPGHQPEATNLISVAVKVLHPGLLAQVHMDLLLMKIGSRVLGVLPGIKWLSLPEIVEEFEKLMVQQIDLRYEAQNLEHFQVNFRNVKAVKFPTPLRPFVTREVLVETYEESVPVSSYQQAG---IPVDLKRKIARLGINMLLKMIFVDNFVHADLHPGNILVQGANG-------LSSSQEAQLQQADICDTLVVAVPS----------SLCPLRLVLLDAGIVAELQAPDLRNFRAVFMAVVMGQGQRVAELILHHAR-ASECRDVEGFKTEMAMLVTQARKNTITLEKLHVSSLLSSVFKLLMTHKVKLESNFASIVFAIMVLEGLGRSLDPKLDILEAARPFLLTG-----PVCPP-----------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9PXA8-1", "uniprot_id": "A0A8M9PXA8_DANRE", "id": "A0A8M9PXA8-1", "name": "", "aln": "----------MSVFCTRHLLHSFKCFARRLPIPT-----QSRRVFFVKATRLLSQTPKVGLFCWTACGTIYAAGPESLKN--------HQNPTERKSVAGV------QIHRLVFVLRLGLRALVLLLKFSPLLLLYPLTLLSQRWAS------------HWLDCLLWVTETSGPTFIKLGQWASTRRDIFSQDFCDRFSRLHVRVKAHSWSHTKLCLKRAFGEGWRQMFVFDS-KEPVGSGCVAQVYRAKAKVANIQDPAFQKLLEELEKK------NLLEAWEIP-------GLGGALSDFWEINRDEDEMTDGKMKEFGER--SGQGEHLEEERLIPVAIKVLHPGIRQQVQIDLILMKAGSLFLNCLPGVKWLSLPEIVEEFQKLMTKQIDLRFEAQNIEKFQKNFKDLEYVKFPTPLRPFVTRTVLVETYEESEPISKYLSSN---IPAGVKQRIARMGVDLLLKMVFVDNFVHGDLHPGNILVQGSCG-------EES--EDRATLTDLWDTVVVSMRA----------TPPSLQLVLLDAGIVAQLSEADQRNFRAVFTAVVLRQGERVAELILHHAR-ANECQDVMRFKKEMAELVDRALSDTLSLGKIQVAELLSQVFGLLIHHKVKLESNFASMVFAIMVLEGLGRSLDPNLDILEMAKPLLLKN-----CTSLL-----------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q02981-1", "uniprot_id": "YP109_YEAST", "id": "Q02981-1", "name": "ABC1 family protein YPL109C, mitochondrial", "aln": "MSFLKFAYRNSWRYYSKSTRHFHKIPIRQFIIPTSIAFYLTQNSFPKQNCLIYNDSLKPDPKGDTFEMGLYVSSENELQEKLKSFRSAKITESRNKLIRYLRIFWFGFNDNIVEPVCTILRFLEISAIFLPLLLLYPISWFGHKLKITDTNITETRGSLIWCQLLRKALELAGPSFIKLGQWAGSRTDIFSHALCHELGKLHSNVTAHSLSFTLEKLSQALKVDKIEDAFDEFNRTPIGVGSIAQVYVGELSQKYIDKYDNIQIGKDGNRW--------------------------------------------------------------------CAIKILHPNVRSQIRRDLKIMKFCADAINWIPTMEWLSLPSEVDQFSILMNIQLDLRIEALNLERFNENFKNSIQVKFPKPFLPLSNRDVMFEEHVYGLSMEKFLSTKKQINDVELCKKVSDPFVDAFLQMLILDDFVHADLHPGNVIIRFVKTNKYGTNIISSELESYRITHDLRKKIEEDQDQDFVGKLKSVLTNYTPQICFIDTGIITELNEKNRINFIALFNALARFDGYRAGELMIERSRTPETAIDKEVFAFKVEKLVDKVKQRTFTLGTVSIGDLLDQMLSMVRSHHVRMESDFVSVVVAILLLEGIGRQLDPNLDLFESSLPILREFGFKREAKSLLKDASTLSMLKIWVGLEVRQLMHLSMKQIYDLVRTDQLCPNY", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : : : : : : : .. * . . :. : ** : * ***:***:: :. * . * . * :**::*******.:* *:**. :* .:.:** .*..*. : * * :*: . . : : *:* *.:**** . . :: :: . *:*:***.: *: ** :** : :. :* ::*****. *::*. ** * *** ** *:*:*: **:: ****.*: *: .* ::.* : . .:..: .: . : :::: :: :::*:::*:***.******:::: .. * :: ..: : . :: ::*:**:::*. : ** *:* *:. :* *..**::.::: .. . * * :: ** :. . .:* .: :..**..:: :: *:*::**:*.*:*.**::***:**.***.**::* : *:* . ", "identical_positions": 134, "similar_positions": 182, "identity": "18.48%" }, { "cls_id": "homologset.agr.MGI:1889341", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D4ABI7-1", "uniprot_id": "D4ABI7_RAT", "id": "D4ABI7-1", "name": "Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase", "aln": "METQVLTPHVYWAQRHRELYLRVELSDVQNPAISISENVLHFKAQGHGAKGDNVYEFHLEFLDLVKPE-PAYRLTQRQVNITVQKKGSHWWERLTKQEKRPLFLAPDFDRWLDESDAEMELRAKEEERLNKLRLESEGSPET---LTNLKKGYLFMYNLVQLLGFSWIFVNLTVRFFILGKESFYDTFHTVADMMYFCQMLALVETLNAAIGVTNSPVLPALIQFLGRNFILFLVFGTMEEMQNKAVVFFVFYSWSAIEIFRYPFYMLSCIDMDWKVLTWLRYTMWIPLYPLGCLSEAVAVIQSIPVFNESGRFSFTLPYPLRMKVRFSFFLQVYLVMLFLG-LYINFRHLYKQRRRRYGQKKKKLH------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8K2C9-1", "uniprot_id": "HACD3_MOUSE", "id": "Q8K2C9-1", "name": "Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase 3", "aln": "METQVLTPHVYWAQRHRELYLRVELSDVQNPAISITDNVLHFKAQGHGAKGDNVYEFHLEFLDLVKPE-PAYRLTQRQVNITVQKKGSHWWERLTKQEKRPLFLAPDFDRWLDESDAEMELRAKEEERLNKLRLEREGSPET---LTNLKKGYLFMYNLVQLLGFSWIFVNLTVRFFILGKESFYDTFHNVADMMYFCQMLALVETLNAAIGVTSTPVLPALIQFLGRNFILFLVFGTMEEMQNKAVVFFVFYSWSAIEIFRYPFYMLSCIDMDWKVLTWLRYTMWIPLYPLGCLSEAVAVIQSIPVFNESGRFSFTLPYPVKMKVRFSFFLQVYLVMLFLG-LYINFRHLYKQRRRRYGQKKKKLH------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9P035-1", "uniprot_id": "HACD3_HUMAN", "id": "Q9P035-1", "name": "Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase 3", "aln": "MENQVLTPHVYWAQRHRELYLRVELSDVQNPAISITENVLHFKAQGHGAKGDNVYEFHLEFLDLVKPE-PVYKLTQRQVNITVQKKVSQWWERLTKQEKRPLFLAPDFDRWLDESDAEMELRAKEEERLNKLRLESEGSPET---LTNLRKGYLFMYNLVQFLGFSWIFVNLTVRFCILGKESFYDTFHTVADMMYFCQMLAVVETINAAIGVTTSPVLPSLIQLLGRNFILFIIFGTMEEMQNKAVVFFVFYLWSAIEIFRYSFYMLTCIDMDWKVLTWLRYTLWIPLYPLGCLAEAVSVIQSIPIFNETGRFSFTLPYPVKIKVRFSFFLQIYLIMIFLG-LYINFRHLYKQRRRRYGQKKKKIH------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q7SY06-1", "uniprot_id": "HACD3_DANRE", "id": "Q7SY06-1", "name": "Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase", "aln": "--MSALTPHVYWAQRHGEIYLRVEISDAQDLSIGVEENILQFRGQGHGAKGENEYEFSLEFLKPVKPE-VKHKSTQRQVNITVRKQEEVWWNRLTKQEKKPLFLAPDFDRWLDESDAEMELREKEE-KINKVSFESRVRKDP---FLGLKKGFLFMYNLVQFLGYSWIFVNMTVRLFILGQDSFYDTFHTIADVMYFCQMLAIMEVINPAVGLVKTGVMPAFIQVMGRNFILFVIFGSLEDMQNKPVVFFVFYLWSTIEIFRYPFYMLACIDTEWKLLTWLRYTIWMPLYPLGVLAEAVAVIQSIPIFDETKLLSIPLPKATGLSLSFSYILQLYLVVMFLG-LFINFRHLFKQRTRRFRTKKRKAN------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VJX8-1", "uniprot_id": "Q9VJX8_DROME", "id": "Q9VJX8-1", "name": "Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase", "aln": "--MANLSPFVYWSQTKQTLLLKVDLKDAKGAIADFSPVSVNFSANGHGARGVNAYKFELHFYALIDDENATFVVSDNKIELQIRKLEPEWWPRLVATPQKPHWLKIDFDRWRTEDDVEVEEKPRDVRQDYEKEYADLQKRELGYIKEKTKKVYMIFYNLAMFVGYLYIMVVMGVLYYRDGVDSIGKTYANVGNAFKFIQLLQYLEVMHPMFGYTKGSPVVPFFQVSGRNFILFLMIDMEPRMYAKPVVFYVFIIWSLVELVRYPYYLAQLLGREVGLLTWLRYTIWIPLYPMGILCEGIIVLRNIPYIEETKRFTVEMPNPWNITFDMVLFLKIYLMLLIIPGSYLVMSHMAKLRSKKLGKGRAKRQQHLHAD", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *:*.***:* : : *:*::.*.:. .. ::* .:****:* * *:* *.* :. * . ::.:::: ::* ** **. ::* :* ***** *.*.*:* : :: : : : :* ::::***. ::*: :*:* : * * :*: .*: .:.: : * *:* :*.::. .* .. : .::*. *******:::. * *.***:** ** :*:.**.:*: :. : :*******:*:****:* *.*.: *::.** ::*: ::. :* . :.. : :*::**::::: :: : *: * * :: : * : ", "identical_positions": 101, "similar_positions": 134, "identity": "27.08%" }, { "cls_id": "homologset.agr.MGI:1889342", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8C503-1", "uniprot_id": "SIT1_MOUSE", "id": "Q8C503-1", "name": "Signaling threshold-regulating transmembrane adapter 1", "aln": "--------------------MSRDYNCTTDDQLAWGIPSISHAWGLWALLGVVTVLLLISLAALLSQWTRGRRRNQEGQGPLSGRSAEEVPLYGNLHYLQTGRLSQEPRSEEQDPPSSGGLARGAEEAMCYTSLQLRPAQGRIPSSGNPIKYCEVVLDSEPKPQAPGPEPELYASVCAQTRRGRASFPDQAYANSQPAPS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q5M869-1", "uniprot_id": "SIT1_RAT", "id": "Q5M869-1", "name": "Signaling threshold-regulating transmembrane adapter 1", "aln": "--------------------MSRENNCTTAD-LAWGIPSITQAWGLWALFGVVTMLLLISLAALLSQWTRGRRRTQEEQGPPSGRSVEEVPLYGNLHYLQTGRLSEESRSEEQDP-SSGGLARGAEEATCYTSLQLRPAQGRIPSSGTPIKYCEVVLDSEPKPQASGPEPELYASVCAQTRRARASFPDQAYANSQPAPS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9Y3P8-1", "uniprot_id": "SIT1_HUMAN", "id": "Q9Y3P8-1", "name": "Signaling threshold-regulating transmembrane adapter 1", "aln": "MNQADPRLRAVCLWTLTSAAMSRGDNC--TDLLALGIPSITQAWGLWVLLGAVTLLFLISLAAHLSQWTRGRSRSHPGQGR-SGESVEEVPLYGNLHYLQTGRLSQDPEPDQQDP-TLGGPARAAEEVMCYTSLQLRPPQGRIPGPGTPVKYSEVVLDSEPKSQASGPEPELYASVCAQTRRARASFPDQAYANSQPAAS", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *** ** * ** *****::*****.*:*.**:*:****** ******** *.: ** **.*.******************::...::*** : ** **.***. *********.*****..*.*:**.*********.**.****************.***************.*", "identical_positions": 132, "similar_positions": 31, "identity": "66.0%" }, { "cls_id": "homologset.agr.MGI:1889348", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "F1M0H0-1", "uniprot_id": "F1M0H0_RAT", "id": "F1M0H0-1", "name": "", "aln": "MGGCGQEKHTRSRSLGTNLLRPRRHTWLVPFNPLSRASGGGMGGGPLCITWSPGEGNWAARQSPSCRPRGGACAPQGARPWCSRGFPAPPHCSPARAAALRVQPRGAWEGGGGGVSARARALQPLAGGARSARPWRRGGAAGRGLLGPRGRRAAVLAAVPAAVEARSGAASSALPVAMYRSGSRSSVSSHRPKDGGASGPPPGRPVGASSGPARRPSSPPP-SCSSLRLPARRHRSPSGHRGRWASPSPPRGRRGSPSPPRGRRASPSPPRGRRASPSPPRGRRVSPSPPRARRGSPSPPRSRRHYPPGLGGFRGSIRGESRADFARDGRGDHPGDSG-SRRRSPGLCSDSSLEQSLRITVGNDHFCVSTAERRRLSDRLGSPVDGLEDMDRDDLTDDSVFTRSSQCSRGLERYISREEGPLSPFLGQLDEDYPTRETFLNRSEYSPQS-RCHDELLRGTERNRDKLKSSSYSVRSEERSREAKRPRYDNLEKAHSTGGDHSGFTSGTRNYRQRRSSPSPRFLDPEFRELDLARRKREEEEEQSKSLSQELVGVDDGQTGCSIPGLSGVLTTAEPGYSLHRSEEIPVMPKKSILKKRIEVD-MKPSLQLESFSSGTSSCEDRPLYSEHSPLPLSDAIAAFTSEIENKGTTVEADLKEPQSNLYQWGPLREIPKDNS---EKFDSFLCFKEKLDLKAEGLEQQTDFLLPHERASQDGSGFSRILSMLADPTSTQEKRRRSFPDIEDEEKFLYGDEEEEDIKSESPPKSLEDAESTGTRQKSNSLP-STPAVKLESLEESNPEYAKIHDLLKTIGLDIGVAEIGKLAARTQERLHGKKPSSRSSADRRS------SAD------RHFSADRCSSVDHSFTTDWHSSDPHRPESREAHHSSTQSPEVSHPHPASLVDSYLRTKNSPPFLKSDRPVGHVSGAEVVGSGFQSSVAVRCMLPSAPSTPIRLPHSAALSQFHIPRASQFAATRISPNYQGTVIPPASFDAYRHYMAYAASRWPMYPASQPPSHPLSDPHRLIPVTKQATRSRPNLRVIPTVTPAKPKQEIPVLGSISVKRIPVRVSIPSLIRYNPKKISDEKNRASQKQKVIEERERLKTEQEARQKKMFYLRTELERLHKQQGEMLRKKRREKDGHKDPLLMEVSRLQEGIMKDIAELHKETEEAGKKQSELDKVAQILGIDIFDKSLKSANDSKESTEKP-EKEKSKSPEKELSPSNPSSNNKESKVN-EKSYIKSPSSTEILQPTAKHPDEPVAAYEYYDAGNHWCKDCNTICGTMFDFFTHMHNKKHTQTLDPYNRPWASKTQSEAKQDTVKRTDKITVPAKGSEFLIPITGFYCQLCEEFLGDPISGEQHVKGHQHNEKYKKYVEENPLYEERRNLDRQAGLAVVLETERRRQNE-------LKRKLNE-------------------------------------------KPKEEKIEKKAKIVKEAKE--------DDKASGELEDQLS------EGRDSPEKGDSKRN-------------------------------------------------------------------------------------------------------------------------------ASLKPQVKEEVKKE----SSTASFGKFSWKKPEK---EEEKNSLVTPGAPKEDTVETNKDRDEGKAEVGKAKPIKIKLSGKTVVAHTSPWTPVVTTSAQTKIRPNLPIPSTALRKSGSATVSKPAPLNTFLSIKSSGASAKPLPVVKESSSDLLLPPDVISKAFGGEEVVLKGS--PEEKVELAEKNEPSQIPEQMLALLPPPPPPPPPPPPPP----------PPP--LVVPQLSAPSPAQANAVLTPVKSNSVVSQTFSLGFQG--------PNILNPGLPVAFMASEQPAAIPCDETAPGVSESDRDQTLISMLVRPPPPLSSVFSEQAKKLEKRNSCLATANAKDLYDIFYSSGGK------GAHETKLSSSPLANGESSSLSRTESSDISSTSALKSSVSPEDLPQDVALATATEISNLENPISKGVESIGKWSIVDQIDPKGRDSTFSFLQPLTRLYQNRPYEMVSPKTDTLAMWTSGSFQNDTDKDRPSEVKIKFDQGEPAPPATDSTS-HPSDEHCQTNGSQKLVEINLMD--NQDK-NQEVYQSEDCRESEGKRNTELKGKVAAEEG--------ANIGLQSIEDSNSNYGNRNTWE---GEPKLSTIDKEAEQSSRLMTGHENTSSIVIELS-QCLPSKRTKIDSFPSLLQ---NPK------GMPELLLLSPAGSGMCLK-----------------------------------------------------------RQETWERPEKPEVEAEELQGTHPEGTVKTESEGSESLDTTHVEVERFATLRNLGDTHAEFCNSQIEQTRRSPTALSQKISEENSVSSVVCNPSSP---SDVEPVPSFSGFPLESPKILVLNFETEGAHSSSNSRNGRITSNS-LETGHPMENVDHDLGG-ERTHQALDLLAGGMLSEEVKEPSPLQK-DLLRMESTTVSPSGHGP-SPCLPDLVDFVTRTPGVPKEKPRSPLSEPDDFLKCSSLEMGSPPPEILNVSVSEVAVPQASEDCDNALNLVKPPTSGSPSRGQVVGGSVSSQEMPEQEAAVDVIPDHRKSSVYNCQDYLNG", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q99PP2-1", "uniprot_id": "ZN318_MOUSE", "id": "Q99PP2-1", "name": "Zinc finger protein 318", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MYRSGSRSSVSSHRSKDGSASGPPPGRPVGASSGPTRRPSSPPPPSCSSLRLPARRHRSPSGHRGRWASPSPPRGRRGSPSPPRGRRASPSPTRGRRASPSPPRGRRGSPSPPRARRGSPSPPRSRRHYPPGLGGFRGSIRGESRADFARDGRGDHPGGGGGSRRRSPGLCSDSSLEESLRITVGNDHFCVSTPERRRLSDRLGSPVDGLQDMDRDDLTDDSVFTRSSQCSRGLERYISREEGPLSPFLGQLDEDYRTRETFLHRPEFSPQS-SCHDELLRGTERNRDKLKSSSYSIRSEERSREAKRPRYDDTEKVHSSGGDHSSFTSGTRNYRQRRSSPSPRFLDPEFRELDLARRKREEEEEQSRSLSQELVGVGDDQIGCSIPGLAGVLTTSEPGYSLQRPEEVPMMPKKSILKKRIEAD-MKPSLQLESFSSGASSGEDHPLYSEHSPLPLSGAIAAFTSEIENKGTTVEADLKEPQSNLYQWGPLREIPKDNS---EKFDSFLGFKEKLDLKAEGLEQQTDFLLPHERASQDGSGFSRILSMLADPTITQEKRRRSFPDIEDEEKFLYGDEEE-DIKSESPLKSLEDPESAGTRQKANSLP-STPAVKLESLEESNPEYAKIHNLLKTIGLDIGVAEIGKLAARTQERLHGKKPSSRPSADRRL------SADRHLSGDRHFSADRCSSVEHSFTADWRSSDPHRPESRETHHSNTQSPEVSHPHPASPVDPYLRTKNSPPFLKSDHPVCHVSGPEVVGSGFQSSVAVRCMLPSAPSTPIRLPHSAALSQFHIPGASQFAAARIPPNYQGSVIPSASFDAYRHYMAYAASRWPMYPASQPPSHPLSDPHRLLPVTKQAARSRPNLRVIPTVTPAKPKQEIPVLGSISVKRIPVRVSIPSLIKYNPKKISDEKNRASQKQKVIEEREKLKTEQEARQKKMFYLTTELERLHKQQGEMLRKKRREKDGHKDPLLMEVSRLQDSIMKDIAELHKETEEAEKKQSELDKVAQILGIDIFDKSLKSSNDSKESTEKP-EKEKSKSPEKELSPSNSSSSNKESKMN-EKSCIKSPSSTESLQPTVKQSDQPVAAYEYYDAGSHWCKDCNTTCGTMFDFFTHMHNKKHTQTLDPYNRPWASKTQSEAKQDTVKRTDKITVPAKGSEFLIPVTGFYCQLCEEFLGDPISGEQHVKGHQHNENYKKYVEENPLYEERRNLDRQAGLAVVLETERRRQNE-------LKRKLNE-------------------------------------------KPKEEKIEKKARIVREVKE--------DDKAPGELEEQLS------EDGSAPEKGEVKGN-------------------------------------------------------------------------------------------------------------------------------ASLRPQVKEEVKKEPSVASIAASFGKFSWKKPEK---EEEKGSVVTPGAPKEDTVETSKDRDDGKAEVGKAKPIKIKLSGKTVIAHTSPWTPVVTTSTQTKIRPNLPIPSTVLRKSGSATVSKPAPLNTFLSIKSSGTSTKPLPVVKESSSDLLLPPDIISKAFGGEEVVLKGS--PEEKVELAEKNEPSQVPEQMLALLPPPPPPPPPPPPPP----------PPPPPQAVPQLSAPSPAQANVVLTPVKSNSVISQTFSLGFQG--------PNILNPGLPVAFMASEQPTVIPSDETAPGVSESDWDQTLISMLVRPPPPLSSVFSEQAKKLEKRNSCLATANAKDLYDIFYSSGGK------GAHETKLSSSTLANGESSSLPRTESSDFSSTCTLNSSMSSEDLPQCSALVTATEISNLENPISKGMESTGKWSVVDQIDPKSRDSTYSFLQPLTRLYQNKPYEIVSPKTDTLVMWTSGSSQNDTHKDRPPEGKIRFDLGEPGPPGTDSTS-HLSDTHCQTNGPQKLIEINLID--NQNK-NQEVYQSEGCRESEMKRKTELKGKVATEEEEEE-----EEEGANSIEDSNSNHGNRNTWEGEIGQPKLSTVDKKGEQSSKLMTGHENTSKVVIELS-PSLPSKRTKIDLFPSLLQ---NPK------SMPELLLLSPAGSGLCLK-----------------------------------------------------------RQEIWERPEKPGLEDVELQGTRPELTVTIESKVLENFDTTHLEVEGFASLRNLGDMHANFHNSQTEQTRRSPTALSEKMSEEISVSSVMCNPSSS---SDIEPVPSFSGFPLESPKTLVLNFETEGAHSSSNSRNGRITSNS-LETGHPVENVGHDLGG-ERTHQALDLLAGGMLSEDVKETSPLQK-DLLRMESTTVSPSGLGP-SPCLPDLVDFVTRTPGVPKQKPCSPLSEPDAFLKCSSLEMGSPPPEILSVSVSEVAVPQVSEDNDSALNLVKTPPSGSPSRDQVVGGNVSPREMPEQEAAVDVIPDHTRSNVYNSQDYLNG", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q5VUA4-1", "uniprot_id": "ZN318_HUMAN", "id": "Q5VUA4-1", "name": "Zinc finger protein 318", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MYRSSARSSVSSHRPKDDGGGGPRSGRSSGSSSGPARRSSPPPPPSGSSSRTPARRPRSPSGHR------------------------------GRRASPSPPRGRRVSPSPPRARRGSPSPPRGRRLFPPGPAGFRGSSRGESRADYARDGRGDHPGDSG-SRRRSPGLCSDS-LEKSLRITVGNDHFCVSTPERRRLSDRLGSPVDNLEDMDRDDLTDDSVFTRSSQCSRGLERYISQEEGPLSPFLGQLDEDYRTKETFLHRSDYSPHI-SCHDELLRGTERNREKLKG--YSIRSEERSREAKRPRYDDTVKINSMGGDHPSFTSGTRNYRQRRRSPSPRFLDPEFRELDLARRKREEEEERSRSLSQELVGVDGGGTGCSIPGLSGVLTASEPGYSLHRPEEVSVMPKKSILKKRIEVDIMEPSMQLESFSSSTSSSQDHPLYSGHPSLPLSGAIAAFASEIENKGTMVETALKEPQGNLYQWGPLPGIPKDNSPLREKFGSFLCHKDNLDLKAEGPERHTDFLLPHERASQDGSGFSRILSMLADSTSTQEKRRRSFPDIEDEEKFLYGDEEE-DLKAESVPKPLGSSESEVMRQKASSLPSSAPAVKLESLEETNPEYAKIHDLLKTIGLDIGVAEISQLAARTQERLHGKKPSLRSSADRRSSVDRYFSADHCSSVDHRFSADRCSSVDHCFSADRRSSDPHRLESREAHHSNTHSPEVSHPHPPSPVDPYLLTKNSPPFLKSDHPVGHISGPEVVGSGFQSSVAVRCMLPSAPSAPIRLPHTAALSQFHMPRASQFAAARIPPNYQGPAIPPASFDAYRHYMAYAASRWPMYPTSQPSNHPVPEPHRIMPITKQATRSRPNLRVIPTVTPDKPKQKESLRGSIPAAQVPVQVSIPSLIRYNPEKISDEKNRASQKQKVIEEREKLKNDREARQKKMYYLRTELERLHKQQGEMLRKKRREKDGHKDPLLVEVSRLQDNIMKDIAELRQEAEEAEKKQSELDKVAQILGINIFDKSQKSLSDSREPTEKPGKAEKSKSPEKVSSFSN-SSSNKESKVNNEKFRTKSPKPAESPQSATKQLDQPTAAYEYYDAGNHWCKDCNTICGTMFDFFTHMHNKKHTQTLDPYNRPWASKTQSEAKQDAIKRTDKITVPAKGSEFLVPISGFYCQLCEEFLGDPISGEQHVKGHQHNEKYKKYVDENPLYEERRNLDRQAGLAVVLETERRRQSE-------LKRKLSE-------------------------------------------KPKEEKKEKKAKAVKEVKE--------DDKVSEKLEDQLS------EGRNSPEKAENKRN-------------------------------------------------------------------------------------------------------------------------------TGIKLQLKEEVKKE---SPTSSSFGKFSWKKPEK---EEEKSSLVTPSISKEEILESSKDKEDGKTEAGKAKPIKIKLSGKTVVAHTSPWMPVVTTSTQTKIRPNLPIPSTVLRKSCSATMSKPAPLNTFLSIKSSGTTAKPLPVVKESSADLLLPPDIISKAFGGEEVILKGS--PEEKVVLAEKSEPSHLPEQIL-----PPPPPPPPPPPP----------PPP---VIPHPAAPSAAQANAILAPVKSNPVVSQTLSPGFVG--------PNILNPVLPVAIMASAQPAAIPSDETAPGVSESDRDQTLFSVLVRPPPPLSSVFSEQAKKLEKRNSCLATANAKDLYDIFYSSGGKGAPETKGAPETKLSGGPLANGENSNLSRTKSSDTSSTSPLNSSASQEELHQDEGLVAAPIVSNSEKPIAKTLVALGKWSVVEHVGPKSTGSTYGFLQPLTRLCQSRPYETITPKTDTLAIWTSSSFQSDTSRDISPE-KSELDLGEPGPPGVEPPP-QLLDIQCKE--SQKLVEIHLRESVNQDKESQELRKSEDCRESEIETNTELKERVKELSEGIVDEGVSTSIGPHSIDDSNLNHGNRYMWEGEVKQPNLLMIDKEAEQSNKLMTGSETPSKVVIKLSPQACSFTKAKLDSFLSEARSLLNPQDTPVKISAPELLLHSPARSAMCLTGSPQEQGVSVVSEEGLENSAPESASRTSRYRSLKLKRERSKDFQVKKIYELAVWDENKKRPETWESPEKPKTEALELQDVHPELTVTIESKALEDFEATDLKVEELTALGNLGDMPVDFCTTRVSPAHRSPTVLCQKVCEENSVSPIGCNSSDP---ADFEPIPSFSGFPLDSPKTLVLDFETEGERNSPNPRSVRIPSPN-ILKTGLTENVDRGLGGLEGTHQALDLLAGGMMPEEVKESSQLDKQESLGLELKTINSAGLGP-SPCLPDLVDFVTRTSGVQKDKLCSPLSEPGDPSKCSSLELGPLQLEISNASTTEVAILQVDDDSGDPLNLVKAPVSRSPPREQVIEDNMVPQGMPEQETTVGAIQDHTESSVHN-------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M2B2U4-1", "uniprot_id": "A0A8M2B2U4_DANRE", "id": "A0A8M2B2U4-1", "name": "", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MFRG--------TRPHRGGYRHPPPSRGFGPRPGPGHPPD----------RDPYRRPS--------------------------------------------PRRRYSPPDPADEYRGG-RPQRGYGRYSP-----------------------------------SPPRGGGLPVDHSLVITVGNELNSPSSFKG------------TDAPYVRDYAAGDSQYKKSYYSPRRSSYDEHGDKGSKRRSVSRGRSRGRSRSPGYGRSKSRPRSRSRSRSYSRGRSRGRSPERAK---SRGRSKSRPRGRSYSRSRSRSRSRSRDKSRARSRARSKSRPRSRSRERSRSRGRSRGRSRARSRSSSSSSSGSSRSRHSSVSRRSKSGKFQSEQEDFSELEKARRRKEIQDTLIKPAKSILKKRVDSSETDSPMLMQISDSPRGNSDGG--LSHEAEQLLCALSKTMDPSVLSSMLGKSSDGNVLEELISKIHPSREDLGDLFLAREKGRQTSDLTEFLGMIAEVAQQHNPKKSLTEIEDEEKFLYGDELEADEVTPAKEIATDSSYPDTREHGTAPYSFTRT----VENVPSRSSATPEVHAEEEPHDFP-PGVGPQDVTVRNEVEEYEKIQDLLKTIGLDLGVAEISKMAARTQERLHGSIPAKKTPVRRQS---------------DRKHRSRSRSSSSSSGSGSRSSSRSQSESRSRSRSRSRSGSLNHTSSRSKKKSVSPEKASPHVHSQSK---KDTQPAVPESNWPTTPTPAQSYPSRPGVLPHPPYPGPPPRGIMP-----------PDYR-----THGYGAYGNYIPYMPPGWPMYP---PTGMPVPPPSQMDPYS-LPNMERPFLKTIKNVTSESKADN----TKKAPSKLDAVASKAITTDHFQRKEMEDKNTASQKQKVTEELEKLRMERDVRQKRKENLLKDVETLRKQQGELLRKKRREKDGHKDPLLVELGRLQEDAMAQISKLRSEQKEADQKHEELVKVALILGIDKEWKISSAHSQQQS-------KDSARSPEKSVAKTNTSYNKVASLKS----RASPEKLKTSPLSSSHSLDTAAEQFEYYDAGNHWCKNCNVTGGSMFDYFMHLHSKTHRKTLDPYDRPWA-KTESEKKGPAGKKTS---KPAKGSEFLVPVRGFFCQLCEEFFGDPICAESHVTCHTHNEKYKAKLYENPLYEQRRKLDRQAGLESQKSSVLKRKHEDDDQDDVKKSKYNKEGKLSSNAMDTKPQYSKEEDHRDIKENDSKHKDKYKKDEYDKLKYKEEEEDERARIKKEEEEKSRYKKDDDERNRYKKEEECSRRYRKREGESSRYEEDHYRNRDDDDDEYHRYKDDDDRYRYRKDDDRGRYSREDEKPRYDKEEDKRYKYTREVEEKSKYKGENWGKWPKSKWDEDQESGGKFDKKDDKTPYQKGKAGLFRDDKASAGMSNVKDVKTEPEKPIEPPKILCGPSPALLAKLRKKNEEAAGRPGFGKFSRKKPQKTALEKEAERMAAQFLKEDEVEKEEEELDPFSKSVAAAKSIAIKLTGKAMIPPSGEWLAFNENKSNTNLPP--PLSPMVIRKSFSGVPNKPTPP---------ALSDKFPAPLTGTQKGTALSADLISKAFSGEEVQLKQAKLLESPVEIFNKPAPPPFPTPSPISSSAPSPAPPSAPSPAPSSAPLPSLSPAPSSAQLPAPASSSALSSTQSSAPSPAPPLVPSSTPPPVLSPAPTLTAAPEIVKPSQLKPVLQPERVVTLESDVAAPGVPEQERKQ---TLVLRPPPQHPSNVRAQPPKMVKP-KTLAAGKAKDLFDIFYSGGTTAKTSVSALVVNKQDPGFAHSNSGSTCKNSNNKDKKACDIFQGKVLPSNGHSQVTANEESLKNKEANVAERKDDNEDSKIAQNKESSKNEDLNVVKSEESSNNEYSEVAQSKEPLNEDLDIESKESSKNEDPKVTQSKESFNEEDSEVALSKDSSKSEHLKFSPCEDSSVNEDSEVAQNEEGLSNE-DSEMAQSDESPKNEDLSISQSEDSPTNENSEVAQ-----SEEPLSNEDSEVLQSDESPLN--VELKVSESEDSPINEDSEIAQSEEPLSNEDSEVVQSDESPQNVELKVSESEDS----PVNEDSEVVQSETLHKEDTEVSQSEESP---------------------------------------------------------KNQDLNSSESENSPVNEDSEVAQSETLNKEDTEMAQSEESPKNEDLNASESEDSQVNEDSEIAQSETLNKEDTEMAQSEESPKNEDLNASESEDSQVNEDSEIAQSDTPNNGDTEVSQSEESPKNEDLNASESENSPVNEDSEVAQSDILNNEDTEMAQSEESPKNKDLNASESENSPVNEDLEVAQSETLNNKDTEVVQGEESPKNEDLHVEQSFEAILKPDIQNENVDAKENLDDQQAFKSIDITMG--DVTDMEVNSVDTLLQTNNEELPLDSEEPMAFSPLPGSFTEQLNLDTFEFSFEPL----------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9V468-1", "uniprot_id": "Y9776_DROME", "id": "Q9V468-1", "name": "Zinc finger matrin-type protein CG9776", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MDEDSATIQLGDRRLGNAVDHDLLPGPPGVDEKSGNENCEPRSSGSGK---RGKSNSRRRSTSRGRSDSRNTSPSNTRRRHSLSRSLTPPRRRYDSPDYGR---------YSRRRFDRDRRRSPERRRSPPRRGRRYGRSRSRSMSPRRGGRWSPKKK------------------PSSPPVPPPHGGPHPQMTPGYGAMAAHIYGSYVAPPDVYGHQYG----------------------IPPNSFPPQGPGYGIPGAPPDQSSFGSGYGPPPTSAWDVN-----------------------------------------VYGQQVWINQPISGVQPSASDSLIQPQKARETLSG---------------------------------------------------------KTIGEEQSVPALEGAGLTPQDAVAQEAEKQKDELKKQR-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ANYVKKVSLLKKEMKVLKDQRED-----------LAAGDAPPSPTTKNFIEENDRLQMQIKKKLDTIENVIDMLNGIIGYEEVED----------EPSNQKSHGKTQPEQQDSRSHSSSESSADSSESSSSSSTASDSSSDNEDGEGAGG-----------------------------------AVGSPTNRLKHRAIKSMKSKQLHG---------------EMKAVPTQAQNYNFVFFDPEQHWCESCGVFPKSARDYLKHLHAEEHMN-RETIETPWHVGIDHDP-FPTFENAPARRVPVRGMQFLVPANAWFCKLCSVWIGDLHCASAHLKSRLHSNKYQQFLNQNPNYEIEWQTNRERAMNQQKDHDDAKNKK------------------------------------------------------------SKKDEDKASKKRKKKG----------------------------GDKKKKKRKHGKK---------------------------------------------------------------------------------------------------------------------------------------------------------------------SKRSTIDANSTSSSSDSSSSEEENGQQPKKGRTEQQPICQSDKSTNAASIRVAMRKQESTPTNLKPEVPCQPVVP--------PPP-----------------------------------------------------------------------------------------------------------------------------------------------------------PIIKDSTIPSERGKWTAASVEDQSKDQKNRDDTMLKQWNNVQPVISESEKKLLEQLKGRLKNKGARDQNNHKAVPTEANDE---------------KFRRGGGRHSRSRSKRRSYSRSISRGRDRDRRDRERDRDRGRRRRSRSRGRHFSRSPIRSSRRSRSRQGRSRRSRSRSIERVERPVVKHSEFRPRTVPERKQTDIKRDKKDAESKSKSSKPSNNSLPGGKKLPFIGKMP--------------------VFKKQSVPSFNYDASAVYTNGCLEAPPPPPPPLGG-----------------------------------------------------ATSQIAVRQQAPTAAQIQMAMMEDAFG---------------------------------------------------------------------------------------------------------------NAPPFHPDAGMMVDYDELMPDPVQFANLMTSCPPPPPPGEGSEGDAHGPEDGDQHDNENREDVLPPGIDEAESALVPHPLDAAAQSRDGELPKDLVEALDIIFPSDVAILEASNGNSEKQEDVTITTIVEDDAVLSVIHLQDLAKEGIHLVTINEAEVPKKSHIQTSEKIEKLQDLNGKSDDGVNIKLIDAEDIPMPNSPPAEPSFDEETKSKALQKQADISEIPEPAVSPSDSEKLRRQSELDELAMLGIDRSDMAAQYAL-------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ** : *. . .:.. : : . ** . .*. . :. .:* * . . * * * . * . *.*. . . . . : . : * . : :: . .. . . . . * * :. : . : * : .. . **** : .*. : . .*: : . : :: : ::.: . : . : *: . ::* : : : .:..: * .::. : ::::. .*... . ... :. .: ::. ** : . : . . : : ::*. .***:.*.. : *:: *:* : * : :. : ** : : : :.: *.:* :**:* .::*:**. ::** ... *:. : *.::*: : :** ** . : :*: .: . :: : .:: :.:* :: : . . : . : .: : : ... . .:: : . . . :: * :.*: . : .: *:: * * . . * * . : . : .. . :.: .: . . * .. :: . .: . :: : ... .. . .:: . . . : . . : . : .: . .. * . : . . .. : .. . : . : : . : . . :: . : . ..: : : :: . . . : . . .: : . .:. . :. : : . : . . : : . . : :: : . . * : . : . * .* :: . . .. : :: . : : ", "identical_positions": 72, "similar_positions": 341, "identity": "2.63%" }, { "cls_id": "homologset.agr.MGI:1889364", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q25C79-1", "uniprot_id": "AKIR2_RAT", "id": "Q25C79-1", "name": "Akirin-2", "aln": "MACGATLKRTLDFDPLLSPASPKRRRCAPLSAPASAAASPAAATAAAAA--SAAAASPQKYLR--MEPSPFGDVS-SRLTTEQILYNIKQEYKRMQKRRHLEASFQQTDPGCSSDSQPHAFLISGPASPGTSSATSSPLKK-EQPLFTLRQVGMICERLLKEREEKVREEYEEILNTKLAEQYDAFVKFTHDQIMRRYGEQPASYVS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "B1AXD8-1", "uniprot_id": "AKIR2_MOUSE", "id": "B1AXD8-1", "name": "Akirin-2", "aln": "MACGATLKRTLDFDPLLSPASPKRRRCAPLSAPASAAASPAAATAAAAA--SAAAASPQKYLR--MEPSPFGDVS-SRLTTEQILYNIKQEYKRMQKRRHLEASFQQADPGCTSDSQPHAFLISGPASPGTSSATSSPLKK-EQPLFTLRQVGMICERLLKEREEKVREEYEEILNTKLAEQYDAFVKFTHDQIMRRYGEQPASYVS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q53H80-1", "uniprot_id": "AKIR2_HUMAN", "id": "Q53H80-1", "name": "Akirin-2", "aln": "MACGATLKRTLDFDPLLSPASPKRRRCAPLSAPTSAAASPLSAAAATAASFSAAAASPQKYLR--MEPSPFGDVS-SRLTTEQILYNIKQEYKRMQKRRHLETSFQQTDPCCTSDAQPHAFLLSGPASPGTSSAASSPLKK-EQPLFTLRQVGMICERLLKEREEKVREEYEEILNTKLAEQYDAFVKFTHDQIMRRYGEQPASYVS", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A5WVY2-1", "uniprot_id": "A5WVY2_DANRE", "id": "A5WVY2-1", "name": "Akirin-2", "aln": "MACGATLKRTMDFDPLMNPASPKRRRCAPMSP-------------------SSSSASPQKYLR--MEPSPFGRVS-SALTTEQILSNIKQEYKRMQKRRHLESSFQQTDSCCPLDSQPHAS----SSSTGSSSGSASPSRR-EQPLFTLRQVGMICERLLKEREEKVREEYDEILTTKLAEQYDAFVKFTHDQLMRRFGEQPASYVS", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VS59-1", "uniprot_id": "AKIRN_DROME", "id": "Q9VS59-1", "name": "Akirin", "aln": "MAC-ATLKRALDWES-MNQRPPKRRRCNPFGQAGSNAGPASPSRDGPSTSAGLPHTPSNRFAKDSTEPSPFSESSLAKMSPDKMAESLCNEIKRLHKRKQLPITSSALERMQDSESSGSEM---GPESPRRPDSPQNLMRHGEKALFTFKQVQLICESMIKERENQLRERYESVLTTKLAEQYDAFVKFTYDQIQRRY-EAAPSYLS", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*** *****::*::. :. .****** *:. . . :..::: : *****. * : ::.::: .: :* **::**::* : . : ::. . *. .... . :: *:.***::** :*** ::****:::**.*:.:*.**************:**: **: * ..**:*", "identical_positions": 68, "similar_positions": 70, "identity": "32.85%" }, { "cls_id": "homologset.agr.MGI:1889371", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8BH06-1", "uniprot_id": "I17RE_MOUSE", "id": "Q8BH06-1", "name": "Interleukin-17 receptor E", "aln": "MGSPRLAALLLSLPLLLIGLAVSARVACPCLRSWTSHCLLAYRVDKRFAG----------------------------------------LQWGWFPLLVRKSKSPPKFEDYWRHRTPASFQRKLLGSPSLSEESHRISIPSSAISHRGQRTKRAQPSAAEGREHLPEAGSQKCGGPEFSFDLLPEVQAVRVTIPAGPKASVRLCYQWALECEDLSSPFDTQKIVSGGHTVDLPYEFLLPCMCIEASYLQEDTVRRKKCPFQSWPEAYGSDFWQSIRFTDYSQHNQMVMALTLRCPLKLEASLCWRQDPLTPCETLPNATAQESEGWYILENVDLHPQLCFKFSFENSSHVECPHQSGSLPSWTVSMDTQAQQLTLHFSSRTYATFSAAWSDPGLGPDTPMPPVYSISQTQGSVPVTLDLIIPFLRQENCILVWRSDVHFAWKHVLCPDVSHRHLGLLILALLALTALVGVVLVLLGRRLLPGSGRTRPVLLLHAADSEAQRRLVGALAELLRTALGGGRDVIVDLWEGTHVARIGPLPWLWAARERVAREQGTVLLLWNCAGPSTACSGDPQAASLRTLLCAAPR-PLLLAYFSRLCAKGDIPRPLRALPRYRLLRDLPRLLRALDAQPATLASSWSHLGAKRCLKNRLEQCHLLELEAAKDDYQGSTNSPCGFSCL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6AZ51-1", "uniprot_id": "I17RE_RAT", "id": "Q6AZ51-1", "name": "Interleukin-17 receptor E", "aln": "MGSPRLAALLLSQPLLFICLAVSAQVACPCLPRWTSHCLLAFRVDKHFAG----------------------------------------LQCGWFPLLVRKSKSSHEFEVCWRHWTPSPFQRKLLGSPSLSQESHRISTHFLAISHRGLRTKRTQPSAAEGIEHLPGAGSQKHGGPEFSFDLLPEVQAIRVTIPPGPEANVRLCYQWALECEDMSSPFDTQKIVSGGHTVDLPYEFLLPCMCIEASYLQEDTVRHKKCPFRSWPEAYGSDFWKSIRFTDYSQHSQMVMALTLRCPLKLEASLCWRQDPVTPCKILPNATAKESEGWYILENVDLHPQLCFKFSFENSSHVECPHQSGSLPSWTVSMDTQAQQLILHFSTRTYATFSAAWSNPGLGLDSSMTPVYSISQTQGSVPVTLNLIIPFLRQGSCILVWRSDVQFAWKHLLCPDVSHRHLGLLILALLGLTTLLGVVLVLFCRRLLPGPGRTRPVLLLHAADSEAQRRLVGALAELLRTALGGGRDVIVDLWEGTHVARIGPLPWLWAARERVAREQGTVLLLWSCAGPSTACSGDPQTASLRTLSCAAPR-QLLLAYFSRLCAKGDIPGPLRALPRYRLLRDLPRLLRALDARPATLATSWSHLGAKECLKSRLELCHLLELEAAKDDYHGSTNSPCGFSCL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8NFR9-1", "uniprot_id": "I17RE_HUMAN", "id": "Q8NFR9-1", "name": "Interleukin-17 receptor E", "aln": "MGSSRLAALLLPLLLIVIDLSDSAGIGFRHLPHWNTRCPLASHTDDSFTGSSAYIPCRTWWALFSTKPWCVRVWHCSRCLCQHLLSGGSGLQRGLFHLLVQKSKKSSTFKFYRRHKMPAPAQRKLLPRRHLSEKSHHISIPSPDISHKGLRSKRTQPSDPETWESLPRLDSQRHGGPEFSFDLLPEARAIRVTISSGPEVSVRLCHQWALECEELSSPYDVQKIVSGGHTVELPYEFLLPCLCIEASYLQEDTVRRKKCPFQSWPEAYGSDFWKSVHFTDYSQHTQMVMALTLRCPLKLEAALCQRHDWHTLCKDLPNATARESDGWYVLEKVDLHPQLCFKFSFGNSSHVECPHQTGSLTSWNVSMDTQAQQLILHFSSRMHATFSAAWSLPGLGQDTLVPPVYTVSQARGSSPVSLDLIIPFLRPGCCVLVWRSDVQFAWKHLLCPDVSYRHLGLLILALLALLTLLGVVLALTCRRPQSGPGPARPVLLLHAADSEAQRRLVGALAELLRAALGGGRDVIVDLWEGRHVARVGPLPWLWAARTRVAREQGTVLLLWSGADLRPVSGPDPRAAPLLALLHAAPRPLLLLAYFSRLCAKGDIPPPLRALPRYRLLRDLPRLLRALDARPFAEATSWGRLGARQRRQSRLELCSRLEREAARLADLG-----------", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "***.*******. *:.* *: ** :. * *.::* ** :.*. *:* ** * * ***:***.. *: ** *:. ***** **::**:** ***:* *:**:*** .* * ** .**: ************.:*:****..**:..****:*******::***:*.**********:*********:*************:*****:***********:*::*******.****************:** *:* * *: ******:**:***:**:************* **********:***.**.********** ****:* :******** **** *: :.***::**::** **:*:******* *:*******:*****:******:***********.* :*:****.* ** .*.* :**************************:*************** ****:********** *************. *. .... **::*.* :* **** **************** ***********************:* : *:**.:***:. :.*** * ** ***: * ", "identical_positions": 437, "similar_positions": 104, "identity": "64.45%" }, { "cls_id": "homologset.agr.MGI:1889376", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "B5DEZ3-1", "uniprot_id": "B5DEZ3_RAT", "id": "B5DEZ3-1", "name": "", "aln": "MFRTISRKNMSQKLSFLLLVFGLIWGLMLLHYTLQQPQRQSSVKLREQILDLSKRYVKALAEESRSTADVDGGASMAGYADLKRTIAVLLDDILQRLVKLESKVDYIVVNGSATNTTNGTNGNLVPVTTNKRTSVSGSVR", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8BIS8-1", "uniprot_id": "CC126_MOUSE", "id": "Q8BIS8-1", "name": "Coiled-coil domain-containing protein 126", "aln": "MFRTISRKNMSQKLSFLLLVFGLIWGLMLLHYTLQQPRRQSSVKLREQILDLSKRYVKALAEESRSTADVDSGASMAGYADLKRTIAVLLDDILQRLVKLESKVDYIVVNGSATNTTNGTNGNLVPVTTNKRTSVSGSVR", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q96EE4-1", "uniprot_id": "CC126_HUMAN", "id": "Q96EE4-1", "name": "Coiled-coil domain-containing protein 126", "aln": "MFFTISRKNMSQKLSLLLLVFGLIWGLMLLHYTFQQPRHQSSVKLREQILDLSKRYVKALAEENKNTVDVENGASMAGYADLKRTIAVLLDDILQRLVKLENKVDYIVVNGSAANTTNGTSGNLVPVTTNKRTNVSGSIR", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "** ************:*****************:***::************************.:.*.**:.*****************************.***********:******.************.****:*", "identical_positions": 124, "similar_positions": 15, "identity": "88.57%" }, { "cls_id": "homologset.agr.MGI:1889377", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q99JT5-1", "uniprot_id": "KRCC1_MOUSE", "id": "Q99JT5-1", "name": "Lysine-rich coiled-coil protein 1", "aln": "MKHSNKPYDSFQDELEDYIKVQKARGLEPKTCFRRMRGEYLESCGYREEFDSRPRYRMFDQRLPSGTNHSYPRSCSSSQT-EDRVPQWLPAHD-KIRLNSLSYCQFTRDGFSEKPVPLNLSQQEYNCGSYSVESVVHKRLCSEHSTIDPQVSHRQMHQKRKKHVEEGREK-QEERPKHERKRSSEEMDLNKHRSIQRKKTKAETETVQDGTEKLKNRKEKKTRDVSSKKEDRKRRKEKKEQGEERTEEEMLWDQSILGF", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q5PPL1-1", "uniprot_id": "KRCC1_RAT", "id": "Q5PPL1-1", "name": "Lysine-rich coiled-coil protein 1", "aln": "MKHSNKPYDSFQDELEDYIKVQKARGLEPKTCFRRMRGEYLESCGYREEFDSRPRYRMFDQRIPSGTNHSYPRSCSSSQT-EDRVPQWLPAHD-KIRLNSLNYCQFTRDGFSEKPVSLNLSQQEYNCGSYSVESVVHKDLCSGHSTIDPQVSHRQMYQKRKRHLEEGRER-QEERPKHERKRSSEEMDLNKHKSIQRKKTKAETETVQDGTEKLKNRKEKKNRDVSSKKEDRKRRKEKKEQGEERTEEEMLWDQSILGF", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9NPI7-1", "uniprot_id": "KRCC1_HUMAN", "id": "Q9NPI7-1", "name": "Lysine-rich coiled-coil protein 1", "aln": "MKHSKKTYDSFQDELEDYIKVQKARGLEPKTCFRKMKGDYLETCGYKGEVNSRPTYRMFDQRLPSETIQTYPRSCNIPQTVENRLPQWLPAHDSRLRLDSLSYCQFTRDCFSEKPVPLNFNQQEYICGSHGVEHRVYKHFSSDNSTSTHQASHKQIHQKRKRHPEEGREKSEEERSKHKRKKSCEEIDLDKHKSIQRKKTEVEIETVHVSTEKLKNRKEKKSRDVVSKKEERKRTKKKKEQGQERTEEEMLWDQSILGF", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "****:*.***************************:*:*:***:***: *.:*** *******:** * ::*****. .** *:*:******** ::**:**.******* ******.**:.**** ***:.** *:* :.* :** *.**:*::****:* *****: :***.**:**:*.**:**:**:*******:.* ***: .***********.*** ****:*** *:*****:****************", "identical_positions": 186, "similar_positions": 51, "identity": "71.81%" }, { "cls_id": "homologset.agr.MGI:1889383", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I5ZVG9-1", "uniprot_id": "A0A8I5ZVG9_RAT", "id": "A0A8I5ZVG9-1", "name": "AP complex subunit sigma", "aln": "---MQFMLLFSRQGKLRLQKWYVPLSDKEKKKITRELVQTVLARKPKMCSFLEWRDLKIVYKRYASLYFCCAIE-DQDNELITLEIIHRYVELLDKYFGSVCELDIIFNFEKAYFILDEFLLG-GEVQETSKKNVLKAIEQADLLQEDAKEAETPRSVLEEIGLT", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9DB50-1", "uniprot_id": "AP1S2_MOUSE", "id": "Q9DB50-1", "name": "AP-1 complex subunit sigma-2", "aln": "---MQFMLLFSRQGKLRLQKWYVPLSDKEKKKITRELVQTVLARKPKMCSFLEWRDLKIVYKRYASLYFCCAIE-DQDNELITLEIIHRYVELLDKYFGSVCELDIIFNFEKAYFILDEFLLG-GEVQETSKKNVLKAIEQADLLQEDAKEAETPRSVLEEIGLT", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P56377-1", "uniprot_id": "AP1S2_HUMAN", "id": "P56377-1", "name": "AP-1 complex subunit sigma-2", "aln": "---MQFMLLFSRQGKLRLQKWYVPLSDKEKKKITRELVQTVLARKPKMCSFLEWRDLKIVYKRYASLYFCCAIE-DQDNELITLEIIHRYVELLDKYFGSVCELDIIFNFEKAYFILDEFLLG-GEVQETSKKNVLKAIEQADLLQE---EAETPRSVLEEIGLT", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P35181-1", "uniprot_id": "AP1S1_YEAST", "id": "P35181-1", "name": "AP-1 complex subunit sigma-1", "aln": "MTQLKYLLLVSRQGKIRLKKWYTAMSAGEKAKIVKDLTPTILARKPKMCNIIEYNDHKVVYKRYASLYFIVGMTPDVDNELLTLEIIHRFVETMDTYFGNVCELDIIFNFSKVYDILNEMIMCDGSIAESSRKEVLHHVTVMDTMES----NDNLERVLS-----", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ::::**.*****:**:***..:* ** **.::*. *:********.::*:.* *:********** .: * ****:*******:** :*.***.**********.*.* **:*::: *.: *:*:*:**: : * ::. :. . **. ", "identical_positions": 82, "similar_positions": 48, "identity": "49.7%" }, { "cls_id": "homologset.agr.MGI:1889385", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q5BJU6-1", "uniprot_id": "CRBL2_RAT", "id": "Q5BJU6-1", "name": "cAMP-responsive element-binding protein-like 2", "aln": "MDDSKVVGGKV-----------KKPGKRGRKP------AKIDLKAKLERSRQSARECRARKKLRYQYLEELVSSRERAICALREELEMYKQWCMAMDQGKIPSEIRALLTGEEQNKSQQNSSRHPKAGKTDANTNSLVGN", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q32M00-1", "uniprot_id": "CRBL2_MOUSE", "id": "Q32M00-1", "name": "cAMP-responsive element-binding protein-like 2", "aln": "MDDSKVVGGKV-----------KKPGKRGRKP------AKIDLKAKLERSRQSARECRARKKLRYQYLEELVSSRERAICALREELEMYKQWCMAMDQGKIPSEIRALLTGEEQSKPQQNSSRHPKAGKTDANTNSLVGN", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O60519-1", "uniprot_id": "CRBL2_HUMAN", "id": "O60519-1", "name": "cAMP-responsive element-binding protein-like 2", "aln": "MDDSKVVGGKV-----------KKPGKRGRKP------AKIDLKAKLERSRQSARECRARKKLRYQYLEELVSSRERAICALREELEMYKQWCMAMDQGKIPSEIKALLTGEEQNKSQQNSSRHTKAGKTDANSNSW---", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q642H2-1", "uniprot_id": "CRBL2_DANRE", "id": "Q642H2-1", "name": "cAMP-responsive element-binding protein-like 2", "aln": "MDDSKIVAGKV-----------KKPGKRGRKP------AKIDLKAKLERSRQSARECRARKKLRYQYLEELVSSKERAICALREELDMYKQWCLAMDQGKIPSEIKALLTGDEQKTPQSCSNKTTKNSKYSSSSGI----", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VL14-1", "uniprot_id": "RTBP_DROME", "id": "Q9VL14-1", "name": "REPTOR-binding partner", "aln": "MADMEIQSNKMSITEETQVQTRKECGKRGRKPGRKTSTEKLDMKAKLERSRQSARECRARKKLRYQYLEELVADREKAVVALRTELERLIQWNNQLSESNTPTNNDQLLQ--ELGILKQE--------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* * :: ..*: *: ******* *:*:*****************************:.:*:*: *** **: ** :.:.: *:: ** * :. ", "identical_positions": 55, "similar_positions": 23, "identity": "39.29%" }, { "cls_id": "homologset.agr.MGI:1889411", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9ET35-1", "uniprot_id": "TR13B_MOUSE", "id": "Q9ET35-1", "name": "Tumor necrosis factor receptor superfamily member 13B", "aln": "----------------------------MAMAFCPKDQYWDSSRKSCVSCALTCSQRSQRTCTDFCKFINCRKEQGRYYDHLLGACVSCDSTCTQHPQQCAHFCEKRPRSQANLQPELGRPQAGEVEVRSDNSGRHQGSEHG--------PGLRLSSDQLTL-YCTLGVCLCAIFCCFLVALASFLRRRGEPLPSQP-AGPRGSQANSPHAHRPVTEACDEVTASPQPVETCSFCFPERSSPTQESA-------PRSLGIHGFAG-TAAPQPCMRATVGGLGVLRASTGDARPAT", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0ABK0LM99-1", "uniprot_id": "A0ABK0LM99_RAT", "id": "A0ABK0LM99-1", "name": "Tumor necrosis factor receptor superfamily member 13B", "aln": "----------------------------VAMALCPKKQYWDSLKRTCVSCVLTCSQRSQRTCTDFCKFINCRKEQGKYYDHLLGTCVSCDSTCTQHPQQCAQFCEKRPRSQVNLQSELRRPETREVEARPDNLGRYQGSEHS--------PGLRMNSDQLTL-YCTLGVCLCAIFCCFLVALASFLRRRGEPLPSQP-AGQRGSQANSPHG--PMTEARNEVAMPPQPVETCSFCFPERSSPTQESA-------PRSLGIHGFAG-TAAPQPCMRASVSGLAVVRTPTGDERPGA", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O14836-1", "uniprot_id": "TR13B_HUMAN", "id": "O14836-1", "name": "Tumor necrosis factor receptor superfamily member 13B", "aln": "MSGLGRSRRGGRSRVDQEERFPQGLWTGVAMRSCPEEQYWDPLLGTCMSCKTICNHQSQRTCAAFCRSLSCRKEQGKFYDHLLRDCISCASICGQHPKQCAYFCENKLRSPVNLPPELRRQRSGEVENNSDNSGRYQGLEHRGSEASPALPGLKLSADQVALVYSTLGLCLCAVLCCFLVAVACFLKKRGDPCSCQPRSRPRQSPAKSSQD--HAMEAGSPVSTSPEPVETCSFCFPECRAPTQESAVTPGTPDPTCAGRWGCHTRTTVLQPCPHIPDSGLGIVCVPAQEGGPGA", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :** **:.****. :*:** *.::*****: **: :.******::***** *:** * * ***:*** ***:: ** .** .** * .: *** ..** **:** ** ***::.:**::* *.***:****::******:*.**::**:* ..** : * * *:*.: ** . *: .*:*********** :****** * . * * *:. *** : . .**.:: ..: : *.:", "identical_positions": 125, "similar_positions": 67, "identity": "42.37%" }, { "cls_id": "homologset.agr.MGI:1889505", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZEF9-1", "uniprot_id": "D3ZEF9_RAT", "id": "D3ZEF9-1", "name": "Hexosyltransferase", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSVGRRRVRLLGILMTANVFIYLIVEVSKSSSQDKNG-KGGVIIPKEKFWKLSSLPRAYWNREQEKLNRWYNPILNRVANQTGDLFTSPNTSHLNYCEPDSTVMTAVTDFNNLPDRFKDFLLYLRCRNYSLLIDQPKKCAKKP---FLLLAIKSLIPHFARRQAIRESWGRETNVGNQTVVRVFLLGKTPPEDNHPDLSDMLKFESEKHQDILMWNYRDTFFNLSLKEVLFLRWVSTSCPDAEFVFKGDDDVFVNTHHILNYLNSLSKSKAKDLFIGDVIHNAGPHRDKKLKYYIPEVFYTG-VYPPYAGGGGFLYSGPLALRLYNVTDRVHLYPIDDVYTG-MCLQKLGLVPEKHKGFRTFDIEEKNKKNICSYIDLMLVHSR-KPQEMIDIWSQLQSPNLKC----------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9Z222-1", "uniprot_id": "B3GN2_MOUSE", "id": "Q9Z222-1", "name": "N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase 2", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSVGRRRVKLLGILMMANVFIYLIVEVSKNSSQDKNG-KGGVIIPKEKFWKPPSTPRAYWNREQEKLNRWYNPILNRVANQTGELATSPNTSHLSYCEPDSTVMTAVTDFNNLPDRFKDFLLYLRCRNYSLLIDQPKKCAKKP---FLLLAIKSLIPHFARRQAIRESWGRETNVGNQTVVRVFLLGKTPPEDNHPDLSDMLKFESDKHQDILMWNYRDTFFNLSLKEVLFLRWVSTSCPDAEFVFKGDDDVFVNTHHILNYLNSLSKSKAKDLFIGDVIHNAGPHRDKKLKYYIPEVFYTG-VYPPYAGGGGFLYSGPLALRLYSATSRVHLYPIDDVYTG-MCLQKLGLVPEKHKGFRTFDIEEKNKKNICSYIDLMLVHSR-KPQEMIDIWSQLQSPNLKC----------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9NY97-1", "uniprot_id": "B3GN2_HUMAN", "id": "Q9NY97-1", "name": "N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase 2", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSVGRRRIKLLGILMMANVFIYFIMEVSKSSSQEKNG-KGEVIIPKEKFWKISTPPEAYWNREQEKLNRQYNPILSMLTNQTGEAGRLSNISHLNYCEPDLRVTSVVTGFNNLPDRFKDFLLYLRCRNYSLLIDQPDKCAKKP---FLLLAIKSLTPHFARRQAIRESWGQESNAGNQTVVRVFLLGQTPPEDNHPDLSDMLKFESEKHQDILMWNYRDTFFNLSLKEVLFLRWVSTSCPDTEFVFKGDDDVFVNTHHILNYLNSLSKTKAKDLFIGDVIHNAGPHRDKKLKYYIPEVVYSG-LYPPYAGGGGFLYSGHLALRLYHITDQVHLYPIDDVYTG-MCLQKLGLVPEKHKGFRTFDIEEKNKNNICSYVDLMLVHSR-KPQEMIDIWSQLQSAHLKC----------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M2B700-1", "uniprot_id": "A0A8M2B700_DANRE", "id": "A0A8M2B700-1", "name": "Hexosyltransferase", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MDLTLDIPCRCPRCGKGFFKMSNNWNSTKLLGVLMLANFLIYIAVEVSRSHNHDRNAFKKNKMIPKE-FWKKTKVSTAFWNREQERLDDIYYLPLVNASELPPHFRGIPRWLNHS-CKHDVNVTAQIEDFNSLPQRFQDFLLYMGCRSYPLITRAPKVCSKPP---YLLLAIKSLAPHFDRRQAIRESWGRAGILDGQRIATVFLLGNTASTDHFPDLSNMVKHEAELYGDVLQWDYRDTFFNLTLKEVLFLEWFGSHCASAQYVFKGDDDVFVNTRHMLAYLANFSISSTQDLFIGDVITNAGPHRSRQLKYYIPESVFTG-GYPPYAGGGGYLYSGSVGLRLRKISRLVTLYPIDDVYTG-MCLQRLGLVPEKHSGFKTFDIEEKHRENPCAYKGLILVHPR-SPQDMIKIWSWINDPNAICHITSTPKTKKTKYTPL", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q24157-1", "uniprot_id": "BRN_DROME", "id": "Q24157-1", "name": "Beta-1,4-mannosylglycolipid beta-1,3-N-acetylglucosaminyltransferase brn", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MQSKHRKLLLRCLLVLP---LILLVDYCG----------------------------LLTHLHELNFERHFHYPLNDDTGSGSASSG------------------------------LDKFAYLRVPSFTAEVP----VDQPA---RLTMLIKSAVGNSRRREAIRRTWGYEGRFSDVHLRRVFLLGTAEDSEKD------VAWESREHGDILQAEFTDAYFNNTLKTMLGMRWASDQFNRSEFYLFVDDDYYVSAKNVLKFLGRGRQSHQPELLFAGHVFQTSPLRHKFSKWYVSLEEYPFDRWPPYVTAGAFILSQKALRQLYAASVHLPLFRFDDVYLG-IVALKAGISLQHCDDFRFHRPAYKGPD---SYSSVIASHEFGDPEEMTRVWNECRSANYA-----------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VLS8-1", "uniprot_id": "Q9VLS8_DROME", "id": "Q9VLS8-1", "name": "", "aln": "MAAMANLHNTRMLRFFLVLIVVILTIFIYASYSTTSTLTANHVHPAASPPQQLIGSHPGRQPMDQVPPVNSTDKEYNSPPGESSSKQQSVSSRHSQQLPPQQAEIHKRHPQHRLPTIDEDALLDGGSAGASPQVGGPDQTPNVMADELLEEQQYGQSVDGITGNINSSTNNNSSADTLAVKQSIPAQSPQQQLPQSQSQVQPGLSDADLLIPTSNLQKFIENADRILKNITS-NSSTGNPSDMAQLNAVDGKLEVSGVESEKQEPESKVIQEIKEAKKEAAVPLPKSAKPPVPPVKTTKSKVPSAPVDPSKGVATETLYEPGHVDEEIDAERICPKGGEFIKLLVLISSAMSHDAARMSIRQTWMHYG--TRRDVGMAFVLGRGTNETIN----KALTQENFIYGDLIRGNFIDSYNNLTLKTISTLEWADVHCPKAKYILKTDDDMFINVPKLLTFLDKHK---DKRTIYGRLAKKWKPIRNKKSKYYVSVDQFAAGVFPSFTTGPAYVLTGDIVHELYVRSLKTVYLKLEDVFTTGIVAKSLNVKRVQANEFVNRRIS----FNPCNIRNAISVHMI-KSNEQFDLWKKLLDQTTKCK---------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . . *: . : :: . : . : : : * : *.* : * :**.:* : .*:** : * : *:: :: *:: * :** : :.* . ::: : *** ::.. ::* :* : . : * * : *:*:. :. :*.:. . .:: : .* : ::**: : .: : . * . : * ..:: :*. . ", "identical_positions": 34, "similar_positions": 83, "identity": "5.53%" }, { "cls_id": "homologset.agr.MGI:1889506", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8R4S8-1", "uniprot_id": "CRLF2_RAT", "id": "Q8R4S8-1", "name": "Cytokine receptor-like factor 2", "aln": "MRAVTWAIVAMLLPRVLGAIPTRTPRTGGVGDTLSVAIVCHDLESVEVTWGPGSAHHGLSANLSLEFRY-GNQVPQPCPHYFLLDS-VRAGCVLPMG-KGLLEVVLREGGGAKLFSRKKKASAWLRPRPPWNVTLSWVGD-TVAVSCPSHSYPGLEYEVQHRDDFDPE--WQSTSAPFCNLTVGGLDPGRCYDFRVRATPQDFYYGPEARPSKWTGVASLQGVGPTGSCTGPTLPRTPGTPTPPLALACGLAVALLTLVLLLALLRMRRVKEALLPGVPDPRGSFPGLFEKHHGNFQAWIADSQ-----AAVPTVPEQDKDDDVIRPQTKGVETQ-------EDDDVIAPGSP------CLGGGALMSVGGASFLMGDSGYTTL--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8CII9-1", "uniprot_id": "CRLF2_MOUSE", "id": "Q8CII9-1", "name": "Cytokine receptor-like factor 2", "aln": "---MAWALAVILLPRLLAAAAAAAAVTS-RGD---VTVVCHDLETVEVTWGSGPDHHG--ANLSLEFRY-GTGALQPCPRYFLSGAGVTSGCILPAARAGLLELALRDGGGAMVFKARQRASAWLKPRPPWNVTLLWTPDGDVTVSWPAHSYLGLDYEVQHRESNDDEDAWQTTSGPCCDLTVGGLDPARCYDFRVRASPRAAHYGLEAQPSEWTAVTRLSGAASAASCTASPAP-SPALAPPLLPLGCGLA-ALLTLSLLLAALRLRRVKDALLPCVPDPSGSFPGLFEKHHGNFQAWIADAQ-----ATAPPARTEE-EDDLIHPKAKRVEPE-------DGTSLCTVPRPPSFEPRGPGGGAMVSVGGATFMVGDSGYMTL--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9HC73-1", "uniprot_id": "CRLF2_HUMAN", "id": "Q9HC73-1", "name": "Cytokine receptor-like factor 2", "aln": "----MGRLVLLWGAAVFLLGGWMALGQGGAAEGVQIQIIYFNLETVQVTWNASKYSRT---NLTFHYRFNGDEAYDQCTNYLLQEG-HTSGCLLDAEQRDDILYFSIRNGTHPVFTASRWMVYYLKPSSPKHVRFSWHQD-AVTVTCSDLSYGDLLYEVQYRSPFDTE--WQSKQENTCNVTIEGLDAEKCYSFWVRVKAMEDVYGPDTYPSDWSEVTCWQRGEIRDACAETPTP--PKPKLSKFILISSLAILLMVSLLLLSLWKLWRVKKFLIPSVPDPKSIFPGLFEIHQGNFQEWITDTQNVAHLHKMAGAEQESGPEEPLVVQLAKTEAESPRMLDPQTEEKEASGGSLQLPHQPLQGGDVVTIGGFTFVMNDRSYVAL--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M2BF96-1", "uniprot_id": "A0A8M2BF96_DANRE", "id": "A0A8M2BF96-1", "name": "", "aln": "--MINWSLCLLFFPTLLFAWSSAGPDDYDEEE------PIEDIDPDRIVFNISKTPYG----VKVIWRVANNNADPQCFN-------------------------------TEVQYKRQCEKDWERS-----------------------------HRIKLQNNQEEN-----------HLNLSTLSTKMNYDFRIRMK----YECLEKDWSNWTKVQSWGNN--KDVCMVKSSY--------YIWVYILIIMLPLITFLLFCLLIQQRIRKLLLPEVPDPKHLKHKIMDTEQFQWWGNLTQRN-----EDCPTTDVEIIDKSESEEVHQTLVTQ-------PTDTIPEQHDSMYYIYSSETLGENTDLQYSKSVLGYIALEDYNK", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : . :: : :::. .:.:. . :.. :* . . * . : : : :. :.:: :. : : .:.: *.. *.* :* . : *.*: * * . : : : : **:. *::. *:* **** ::: .: :: ::: : . . : .. .: . * : . ::. . ", "identical_positions": 20, "similar_positions": 84, "identity": "5.18%" }, { "cls_id": "homologset.agr.MGI:1889507", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9ERV7-1", "uniprot_id": "PIDD1_MOUSE", "id": "Q9ERV7-1", "name": "p53-induced death domain-containing protein 1", "aln": "-------------------------------------MAA--------VLEGQEPEETAAAAEDAATSTLEAVDAGPGAPFLPA--------------GNQLNLDLRPGGCHRLQYLCSQQPPQLLQVEFLRLSTHEDPQLLDDTLAKVPWSLLRLRSLVLKGGQSRGALGACLHGTLTTLPAGLSDLACLAHLDLSFNRLETLPTCVPELHGLDALLLSHNHLSELPEALGALPALTFLTVTHNRLERLPLTLGSLSTLQRLDLSENLLDTIPSEIGNLRSLSELNLASNRLQSLPASLAGLRSLRLLVLHSNLLTSVPTGLVHLPLITRLDLRDNRLRDLPAELLDAPFVRLQGNPLGEASPAPPSPPDISQVPEMPRLLLTSDLDSFLVTPHGCSVTLACGVRLQFPAGATTTPVTIHYRLWLPEPGLVSLGPHDFLLSSVLELQPHGVAFQQDVSLWLLFVPP--RVRRCREVVVRTRSNNTWNDLETQLEEEAPKR---------LWARCQVPHFSWFLVVLRPVSNTCLLPPEGALLCSSGHPGVRVTFPPGVTEEPRQVSMQVVHMAGLELRTLLEESEASVSPLLCLSQSGPPSFLQPVTVQLPLPPGVTGFSLDRSHLHLLYRTPLTTTWDDITTQVALEFTHLYARFQVTHFSWYWLWYTTKTCVGGLARKAWERLRLHRVNLIALQRRRDPEQVLLQCLPRNKVDATLSRLLVRYRGPEPSETVEMFEGEKFFAAFERGIDVDADRPDCVDGRICFVFYSHLKNVKEVYITTALDREAQDVRGQVSFYRGSLPVEVPAEAEAARQRKGTDALWMATLPIKLPR----------LRGAQGSGQGTDFSLM-PLNLGDAETGFLTQSNLLSVASRLGPDWPAVALHLGMPYHKLQRIRHEFRDDLDGQVRHMLFSWAERQTGQ-PGAVGHLVQALEQSDRRDVAEEVRAILELGRHKYQDSIRRTGLAPEDSTLPGTSASQTPESAQA", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "M0R797-1", "uniprot_id": "M0R797_RAT", "id": "M0R797-1", "name": "p53-induced death domain-containing protein 1", "aln": "-------------------------------------MAA--------VLEGPKPEETAAAAEDAARPTVEAVASRPGVPILLA--------------GNQLNLDLRPGGCRRLQYLCSQQHTQLLQVEFLRLSTHEDPRLLDDTLAKVPWSLLRLRSLVLKGGQSRGALGACLHGTLTTLPASMRDLACLAHLDLSFNRLETLPTCVLELHSLDALLLSHNCLSELPEALGALPTLTFLTVTHNLLERLPPTLGSLSTLQRLDLSENLLDTIPSEIGDLSSLRELNLASNRLQHLPASLAGLRSLRLLVLHSNLLTSVPPGLAHLPLITRLDLRDNQLRDLPAELLDAPFVRLQGNPLGEASPAPPSPPDISQVPEMPRLFLTSDLDSFLVTPHGCSVTLACGVRLQFPAGATTTPITIHYRLWLPEPGLVSLGPHDFLLSGVLELQPHGVAFQQNVSLWLLFVPPRVRVRRCREVVVRTRSDNIWNDLETHLEEEAPKR---------RWARCQVPHFSWFLVVLRPVSNTCLLPPEGALLCSSGHPGVKVTFPPGVTEEPRQVSMQVVHMAGLELRALLEESEAAVSPLLCLSQSGPPSFLQPVTVQLPLPPGVTGFSLDRSHLHLLYRTPLTSTWDDISTQVALEFTHLYARFQVTHFSWYWLWYTTKTCVGGLARKAWERLRLHRVNLIALQRRRDPEQVLLQCLPRSKVDATLSRLLDRYRGPEPSETVEMFEGEKFFAAFERGIDVDADRPDCVDGRICFVFYSHLKNMKEVYITTALDREAQDVRGQVSFYRGSLPMEVPEEAEAARRRKGTDALWMATLPIKLPR----------LRGAQGSGQGTDFSLM-PLNLGDAETGFLTQSNLLSVASRLGSDWPTVALHLGMPYRKLQRIRHEFRDDLDGQIRHMLFSWAESQTGQ-PGAVGHLVQALEQSDRQDVAEEVRAILELGRHKYQDSIRRTGLAPEDSTLPSTSALQNPESAQA", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9HB75-1", "uniprot_id": "PIDD1_HUMAN", "id": "Q9HB75-1", "name": "p53-induced death domain-containing protein 1", "aln": "-------------------------------------MAA--------TVEGPE-LEAAAAAGDAS----EDSDAGSRALPFLG--------------GNRLSLDLYPGGCQQLLHLCVQQPLQLLQVEFLRLSTHEDPQLLEATLAQLPQSLSCLRSLVLKGGQRRDTLGACLRGALTNLPAGLSGLAHLAHLDLSFNSLETLPACVLQMRGLGALLLSHNCLSELPEALGALPALTFLTVTHNRLQTLPPALGALSTLQRLDLSQNLLDTLPPEIGGLGSLLELNLASNRLQSLPASLAGLRSLRLLVLHSNLLASVPADLARLPLLTRLDLRDNQLRDLPPELLDAPFVRLQGNPLGEASPDAPSSPVAALIPEMPRLFLTSDLDSFPVTPQGCSVTLACGVRLQFPAGATATPITIRYRLLLPEPGLVPLGPHDALLSHVLELQPHGVAFQQDVGLWLLFTPP--QARRCREVVVRTRNDNSWGDLETYLEEEAPQR---------LWAHCQVPHFSWFLVVSRPVSNACLVPPEGTLLCSSGHPGVKVIFPPGATEEPRRVSMQVVRMAGRELQALLGEPEAAVSPLLCLSQSGPPSFLQPVTVQLPLPSGITGLSLDRSRLHLLYWAPPAATWDDITAQVVLELTHLYARFQVTHFSWYWLWYTTKNCVGGLARKAWERLRLHRVNLIALQRRRDPEQVLLQCLPRNKVDATLRRLLERYRGPEPSDTVEMFEGEEFFAAFERGIDVDADRPDCVEGRICFVFYSHLKNVKEVYVTTTLDREAQAVRGQVSFYRGAVPVRVPEEAEAARQRKGADALWMATLPIKLPR----------LRGSEGPRRGAGLSLA-PLNLGDAETGFLTQSNLLSVAGRLGLDWPAVALHLGVSYREVQRIRHEFRDDLDEQIRHMLFSWAERQAGQ-PGAVGLLVQALEQSDRQDVAEEVRAVLELGRRKYQDSIRRMGLAPKDPALPGSSAPQPPEPAQA", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AC58IWL1-1", "uniprot_id": "A0AC58IWL1_DANRE", "id": "A0AC58IWL1-1", "name": "", "aln": "MEREEKKQTERKEWPAPPDEEGDAYSFTNKRRAMLMETAAGPDFLGKLETEESPPLGVSLCSEHTDTWAPSIVSSSSSSLPCLSPPLPPSVGLDGVLVEERLVLDVYRGGAEVLPVFWEFVQERMRGLQYLRLGS-EDEGALERALRVLPR-LTQLRSLAIRGCRFHDPQGDPLPGLLSSLPDSVSSLSLLVHLDLSFNRFSSLPSCLLSFSHLSELLLCHNNLTTLPEGIGALASLRRVSLLGNRLVDLPQDLGLLCGLEELDVSFNLLEKLPDELGQLQNLQRLELSNNKLRALPETLGSLRSLRQLLIQSNDLRSVPDCLHSLPMLDKLDVRNNPLGRPPTPPLLAQLT-----PVVEDS-------------EIPELHLRFNQHSFQVSPAGCHVFLPGGAELLFPRQCVGVVTQLQWAEKRPDRKWVWLEEHDVLLSRQLELRPHGATFQKLVGVCIPYRKT-----RKGDVVVRRFDGQSWTTLTTMTRRGSDKHSCRPGGRPARLACCSVSQFSWFVAVCCPFLDSCSVSPEGALLVSQCDPGIKLSFPPNCTAETRTVTLQVLQVALSEVQDLTGDPHASAGPLLRLSQTPSMHFLQPIRVQVPLPPGVTGHMVDLSRLHLMHGDPTAHTWTDVTAQVSLYVTHIYAVFFITHFSWYWLWYTTHRCVSGVVRKMYHRLKQFRVRFLALQRKNDPEQILLQCLPSDKAESRLESLADQYEGPQPSELCVLLEGEQFFAGFERGIDINSDRPDCKDGRLSFTFYSHLKNIKEVYVCATHP-VQTTVRGQVSFYRGEVPSDLP--EEVARKRKGHDDQWMATLPLRIPINMHMIKWSTHLESFVKQKSEIDGSISGELNLGDPESGYLTQTNLLSISLRINQEWQNIGINLGMSYEQLERIRHQHRDNFGAQVLAMLFHWARGQQGTGPGAVQRLMTALVDSGRRDLAEEVEDIVTLGKRKYEESLKRVGLET-----PVTSTE--PQSS--", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ** * .: .: .: . : . . ::* **: **.. * : :: :::***.: ** *: :* :* * ****.::* : :.. * * * *:.** .: .*: *.******* :.:**:*: .: *. ***.** *: ***.:***.:* ::: * * ** ** *. *:.**:* ***:.:* *:* * .* .*:*:.*:*: ** :*..***** *:::** * *** * **:: :**:*:* * *. * * :. *: * * *:*.* * : .** *:* ** * *. *..* ** .. . ::: *: * * ** *** ***:***.:**: *.: : : . * :**** ..: * * * .. : :: * *.*.:****:.* *. ::* :.***:** *. .**::: ***. * *.* *::**:::* *:: * :..*:..*** ***: . ****: **:***.*:** :* *:***:: * : ** *:::** * .**:** * :************: **.*:.** :.**: .**.::****:.****:****** .*.:: * * :*.**:**: ::***:***.******:::***** :**:.*.*******:****: :: ********** :* :* *.**:*** * ******:::* *.. . *: *****.*:*:***:****:: *:. :* :.::**:.*.:::****:.**::. *: *** **. * * **** *: ** :*.*:*:****. :: **::**::*::* ** . * :*: *:.: ", "identical_positions": 374, "similar_positions": 262, "identity": "37.51%" }, { "cls_id": "homologset.agr.MGI:1889508", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I5ZMX5-1", "uniprot_id": "A0A8I5ZMX5_RAT", "id": "A0A8I5ZMX5-1", "name": "TBC1 domain family member 1", "aln": "MEAITFTAR--------------KHPFPN----------EVSVDFGLQLVGSLPVHSLTTMPMLPWVVAEVRRLSGQCSKK----------EPGMKQVRLWVSPSGLRCEPDLR-KSQPWDPLICSSIFECKPQR----VHKLIHNSQDPSYFACLIKEDAAHQQSLCYVFKADDQTKVPEIISSIRQAGKIARQEE----------------LRCPS-EFDDTFAKKFEVLFCGRVTVAHKKAPPALIDECIEKFNHVSCGRRIDWDAPTGQPSAPGA------RPMRKSFS--QPGLRSLAFRKEFQDASLRSS-TFSSFDN-DIENHLIGGHNVVQPTDMEENRTMLFTIGQS-EVYLISPDTKKIALEKNFKEISFCSQGIRHVDHFGFICRECSGGGGAGFHFVCYVFQCTNEALVDEIMMTLKQAFTVAAVQQTAKAPAQLCEGCPLQGLHKLCERIEGMNSSKTKLELQKHLTTLTNQEQ--------------AMIFEEVQKLRPRNEQRENELIISFLRCLYEEKQKEHSHTGEPKQTLQVAAENIGSELPPSASRFRLDSLKNRAKRSLTESLESILSRGNKARGLQDHSASVDLDSSTSSTLSNTSKELSMGDKEALPISESSFKLLGSSDDLSSDSE--SHIAEESALLSPQQAFRRRANTLSHFPVECP-APPEPAQTSPGVSQRKLMRYHSVSTETPHERNVDHLPGGESRCCPGQPSDPPPLPPRLNPSASSPNFFKYLKHNSSGEQSGNAVPKSVSYRNALRKKLHSSSSVPNFLKFLAPVDENNTCDFKNTNRDFESKAN-HLGDTDGTPVKARRHSWRQQIFLRVATPQKACDSPS---RYEDYSELGELPPRSPLEPVCEDGPFGPVQEEKKKTS-RELRELWKKAILQQILLLRMEKENQKLQASENDLLNKRLKLDYEEITPCLKEVTTVWEKMLS-TPGRSKIKFDMEKVHSAVGQGVPRHHRGEIWKFLAEQFHLK-HPFPSKQQPK-DVPYKELLKKLTSQQHAILIDLGRTFPTHPYFSAQLGAGQLSLYNILKAYSLLDQEVGYCQGLSFVAGILLLHMSEEEAFKMLKFLMFDMGLRKQYRPDMIILQIQMYQLSRLLHDYHRDLYNHLEEYEIGPSLYAAPWFLTVFASQFPLGFVARVFDMIFLQGSEVIFKVALSLLGSHKPLILQHENLETIVDFIKNTLPNLGLVQMEKTISQVFEMDIAKQLQAYEVEYHVLQEELID-SSPLSDNQR------------------MDKLEKTNSSLRKQNLDLLEQLQVANARIQSLEVTVEKLLTS----------------------------------------------------ESKLKQAVLTLEMERSALLQMVEELRRQMAQP--STAEPDCTRLEPTGD-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q60949-1", "uniprot_id": "TBCD1_MOUSE", "id": "Q60949-1", "name": "TBC1 domain family member 1", "aln": "MEAITFTAR--------------KHPFPN----------EVSVDFGLQLVGSLPVHSLTTMPMLPWVVAEVRRLSGQCSKK----------EPRTKQVRLWVSPSGLRCEPDLE-KSQPWDPLICSSIFECKPQR----VHKLIHNSHDPSYFACLIKEDAAHRQSLCYVFKADDQTKVPEIISSIRQAGKIARQEE----------------LRCPS-EFDDTFAKKFEVLFCGRVTVAHKKAPPALIDECIEKFNHVSCGRRTDWEAPTGQPSAPGP------RPMRKSFS--QPGLRSLAFRKEFQDASLRSS-TFSSFDN-DIENHLIGGHNVVQPTDMEENRTMLFTIGQS-EVYLISPDTKKIALEKNFKEISFCSQGIRHVDHFGFICRECSGGGSGGFHFVCYVFQCTNEALVDEIMMTLKQAFTVAAVQQTAKAPAQLCEGCPLQGLHKLCERIEGMNSSKTKLELQKHLTTLTNQEQ--------------ATIFEEVQKLRPRNEQRENELIISFLRCLYEEKQKEHSHTGEPKQTLQVAAENIGSDLPPSASRFRLDSLKNRAKRSLTESLESILSRGNKARGLQDHSASVDLDSSTSSTLSNTSKELSMGDKEAFPVSETSFKLLGSSDDLSSDSE--GHIAEESALLSPQQAFRRRANTLSHFPVECP-APPEPAQSSPGVSQRKLMRYHSVSTETPHERNVDHLPGGESQGCPGQPSAPP--PPRLNPSASSPNFFKYLKHNSSGEQSGNAVPKSVSYRNALRKKLHSSSSVPNFLKFLAPVDENNTCDFKNTNRDFESKAN-HLGDTDGTPVKTRRHSWRQQIFLRVATPQKACDSPS---RYEDYSELGELPPRSPLEPVCEDGPFGPVQEEKRKTS-RELRELWKKAILQQILLLRMEKENQKLQASENDLLNKRLKLDYEEITPCLKEVTTVWEKMLS-TPGRSKIKFDMEKVHSAVGQGVPRHHRGEIWKFLAEQFHLK-HPFPSKQQPK-DVPYKELLKKLTSQQHAILIDLGRTFPTHPYFSAQLGAGQLSLYNILKAYSLLDQEVGYCQGLSFVAGILLLHMSEEEAFKMLKFLMFDMGLRKQYRPDMIILQIQMYQLSRLLHDYHRDLYNHLEEHEIGPSLYAAPWFLTVFASQFPLGFVARVFDMIFLQGSEVIFKVALSLLGSHKPLILQHENLETIVDFIKNTLPNLGLVQMEKTISQVFEMDIAKQLQAYEVEYHVLQEELIE-SSPLSDNQR------------------MEKLEKTNSSLRKQNLDLLEQLQVANARIQSLEATVEKLLTS----------------------------------------------------ESKLKQAALTLEVERSALLQMVEELRRQSARP--STPEPDCTQLEPTGD-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q86TI0-1", "uniprot_id": "TBCD1_HUMAN", "id": "Q86TI0-1", "name": "TBC1 domain family member 1", "aln": "MEPITFTAR--------------KHLLSN----------EVSVDFGLQLVGSLPVHSLTTMPMLPWVVAEVRRLSRQSTRK----------EPVTKQVRLCVSPSGLRCEPEPG-RSQQWDPLIYSSIFECKPQR----VHKLIHNSHDPSYFACLIKEDAVHRQSICYVFKADDQTKVPEIISSIRQAGKIARQEE----------------LHCPS-EFDDTFSKKFEVLFCGRVTVAHKKAPPALIDECIEKFNHVSGSRGSESPRPNPPHAAPTGSQEPVRRPMRKSFS--QPGLRSLAFRKELQDGGLRSSGFFSSFEESDIENHLISGHNIVQPTDIEENRTMLFTIGQS-EVYLISPDTKKIALEKNFKEISFCSQGIRHVDHFGFICRESSGGG--GFHFVCYVFQCTNEALVDEIMMTLKQAFTVAAVQQTAKAPAQLCEGCPLQSLHKLCERIEGMNSSKTKLELQKHLTTLTNQEQ--------------ATIFEEVQKLRPRNEQRENELIISFLRCLYEEKQKEHIHIGEMKQTSQMAAENIGSELPPSATRFRLDMLKNKAKRSLTESLESILSRGNKARGLQEHSISVDLDSSLSSTLSNTSKEPSVCEKEALPISESSFKLLGSSEDLSSDSE--SHLPEEPAPLSPQQAFRRRANTLSHFPIECQ-EPPQPARGSPGVSQRKLMRYHSVSTETPHER-----------------------------------------------------------------------------------------------KDFESKAN-HLGDSGGTPVKTRRHSWRQQIFLRVATPQKACDSSS---RYEDYSELGELPPRSPLEPVCEDGPFGPPPEEKKRTS-RELRELWQKAILQQILLLRMEKENQKLQASENDLLNKRLKLDYEEITPCLKEVTTVWEKMLS-TPGRSKIKFDMEKMHSAVGQGVPRHHRGEIWKFLAEQFHLK-HQFPSKQQPK-DVPYKELLKQLTSQQHAILIDLGRTFPTHPYFSAQLGAGQLSLYNILKAYSLLDQEVGYCQGLSFVAGILLLHMSEEEAFKMLKFLMFDMGLRKQYRPDMIILQIQMYQLSRLLHDYHRDLYNHLEEHEIGPSLYAAPWFLTMFASQFPLGFVARVFDMIFLQGTEVIFKVALSLLGSHKPLILQHENLETIVDFIKSTLPNLGLVQMEKTINQVFEMDIAKQLQAYEVEYHVLQEELID-SSPLSDNQR------------------MDKLEKTNSSLRKQNLDLLEQLQVANGRIQSLEATIEKLLSS----------------------------------------------------ESKLKQAMLTLELERSALLQTVEELRRRSAEP--SDREPECTQPEPTGD-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M2BFN8-1", "uniprot_id": "A0A8M2BFN8_DANRE", "id": "A0A8M2BFN8-1", "name": "TBC1 domain family member 4", "aln": "MEGICFEVKPRDDSITAHPLCDLTQTFPGSEEKRKKEDGEEVIQYRLTLVGSLAIHPQTTMAILPWVVAEIRRPRVREKNRNLEFNGNYSPEIRDQPVVLQISASSVCCILDTAGPGKPWNPLQHMVLFDHRPHH----VTKLIHNSQEPSYFGCLLREE---KKAACYVFRCQDQLKVPEIISTLRQAGKSSARQEDTPSLPSNGQSDASSSTATAA-DAATAFAKKFEVLFCGRVVVAHKKAPPALIDECIEKFGRVSVTGSLAAGIRRAFSLNQVVN-------GTNEGD--GGGKRPLFFKRD-QSFPFLQALDENGLSP-ELQRRAADGATGVQPTSLQENRTMLFTIGRS-QIFLVSPDTKKVAIEKSFREISFCSQGIRHVDHFGFICRESVECG--GCQFVCYVFQCANEALVDEIMLTLKQAFSVAALQQNSRTQSQQCDGCPLQQLHKLCDRIEGLHPSKAKLELQKHLADLDNQEQ--------------AAVFESTMKARPKSDQEENELIVSCLRRMYEDRQKTHTHNGQTKKDVVVNAESS-----VSSSRVRLEEFKSRAKRSLTESLEGIWKGGNKSKSQRENSE-GESNSSSSTTLSSTHQETSLQEPLCSLLLSSPLRSHNSTGNLKHLEG--SDRGQE-DPESPPQGFRRRASTISHSPMLSSSEPSLPPLQPTAANKPKLVRHYSVSTDSPHQSNPSSSPASSSPVCQRPLRPRS----------------------FALDHSTRPLKRSPSGLSGFRARLHSSSSVPNFLKFLAPVVESDDTCDSQRKSDVAALSSPGCVIGDDSPLRNRRHSWRQQIFLRVATPQKGSEAKE---STLEVGSRMALGGG----VGGGDKTLGALPEERRKRSGAELRELWRKAILQQILLLRMEKENQKLQASESDLQCKRQKLDYEEITPCLKDVTLVWERMLG-TAGRAKVRFDMDEIHGAVGQGVPRQHRGEIWKFLSEQYLLR-QEVPSAKPPNNDTPYKELLKQLTSQQHAILIDLGRTFPTHPYFSAQLGAGQLSLYNLLKAYSLLDPEVGYCQGLSFVAGVLLLHMSEEDAFHMLKFLMYDMGLRKQYRPDMIILQIQMYQLSRLLHDYHRELYSHLELYEIGPSLYAAPWFLTAFASHFPLGFVARVFDMLFLQGSEVIFKVALSLLGSHKPLILQHDNLEAIVEFIKTTLPNLGLVQMEKTINQVSEMDISKQLQAYEVEYHVLQDELLDGPSTLSHSQR------------------AAQLEKTNGSLRQQNLDLLEELQVAHAKIRCLETRVDGLVNR----------------------------------------------------DAELQSQVKTLQQEQTDLQQTVCKLRDLLSSLGISNPCPDLQILTNNNQ-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "E1JJ52-1", "uniprot_id": "E1JJ52_DROME", "id": "E1JJ52-1", "name": "", "aln": "---------------------------------------MKTRLVSLTFRGSASVDPRYSASMLPWTINDIRSTESYTKLSVGIENG--ILESYNSDFELQFSHPLKHIVGMCRIIHKPQAKSIGNGFLQLKSSAGQTSSSSAVASSMGGAASSSLTGNGLRHTLTASTSYGSLSSSAACAYQLQLQQSAEASAEQPQNFMEFQGPITGLVYLLKDPKDPLLHIYLFECEAVEEMAELMHQMRDPAHTLGGSVGSIPQTLIGGGGGSHGNSNGALNGIHATPATNLKMSEAMRNAQHDTSPNPVSSKMKASKSYTHGLSSSSGTVNIPTSTSAQSNLSLLADISPNHTHFFEVMYVGKIRVSQKRVPNTFIDDALPKFKAYDAQRLRLLQNRKMSLSSEGGVGIEAKPSSSLKSHDLKEEDEEEQEQHKGHDDSQDSQAKPLVQLQLTGAEEGAAPRPLEDNKENKSPEKRPLLRGQSQIELGHKEHSDGSQPLAANSQLEAPNVIVNKQPTPPRDQGVGTGTASASAGPSQLHPNYAMDNIPKQRDRSASQGCIPPYVEQNRTMVFLVGRCDLRLISPDRKQVLLYKDFKDVASCVHGQKSLDHFGIICRELNNDGYIGYVFKCQSEHVCDDIVAAIAQAFDTCAEQKKKQDTQIFSCEHCPMLWYHKLCTDVEGLSEKKTQALILRRIETLSDDEQEIVWAKFCGSEKTNSPVAEQNQFLMMLLRAHCESRQQ--RHVHDTAENRSEFLNQYLGGSTIFMKAKRSLTNSFDNLLKRKPSKDDIAVPSHNLRDIREGSAEPLGTQSPPEGFRSRSNTVGASPSSKPTAEQLKSPMMDIFIKVGNSPKEAETHQGSWRQAILNSVVTPSKGLDSEVPTEFLSPMRKPAKRGKRDAAELRELWRTAIRQTIMLNRMETENAMLQARQNENELKRIKLDYEEIVPCDKQLIERWEQIIERNSTQIGNKKDPKVLGHAIRTGVPRSKRGDVWTFLAEQHSMNTAPVDTKRFPNFNTPYHMLLKHLTEHQHAIFIDLGRTFPNHQFYKDPLGLGQLSLFNLLKAYSILDPELGYCQGLGFICGVLLLHCDEANSFQLLKHLMFRRNMRTKYLPDMKKFQLQLYQLSRLVKDHLPDLYVWLDQNDVSPTLYAAPWILTVFSSQFPLGFVARVFDLLFLESSDVIFKFAIALLSVHKQQLLAKDNFEEIMDYLKTVVPKMEHTCMEQIMKLVFSMDIGKQLAEYKVEYNVLQEEITTTNHHLEMLNREKTQNQHLEQQLQFAQSSIAQLETTRSSQQAQITTLQSQVQSLELTIQTLGRYVGQLVEHNPDLELPNEVRRMLQQLDDLDRQRRKPIFTERKIGKSVSVNSHLGFPLKVLEELTERDELGSPQKQKKEKTPFFEQLRQQQQQHRLNGGGQSSNVGESGSPTPPSRPNRLLDNASARTVMQVKLDELKLPEHVDKFVANIKSPLEVDSGVGTPLSPPSTASNSSGGSIFSRMGYRTTPPALSPLAQRQSYGVAITTAPCPQHMEEVAPATTMAVMPQEDVEEPQPMHPLSMVGGDVNVRFKGTTQLKSIRPVHHMRAIPLGGVQHPSSTEPAVRVAPVPVELAPPAATATTGRS", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * : ** .:.. : .:***.: ::* . * . . * .* . : ::: :. . : .* : ..* : : . : . .. . ::*:.: : .: . : : *.: : : : *. :. .: .: :. : . . . . : .. :: . :.:. *:* :* : :: : . . : ::. : ::. . :: : :. .. : . : . : :* * * .. . * . : * :. *. ..* * : * ::*: * . : * :* . * : : : . :: . : . * . * .. : . :. . . . : . . *.. : . . : . . .: : . . .* ::: .. :. . . . .: ::: .::..:. .. : :. ...* : :* :**::*... * .:: . .. . :: : . ******:.** * *:* ***.** *** :.: ** *******.** *:: **::: .. : : * . : *: **** :**::*.**:**. :. . : : *: :.**: ***:**.:****:********.* ::. ** *****:*:*****:** *:******.*:.*:**** .* ::*::**.**: .:*.:* *** :*:*:******::*: :** *: ::.*:******:** *:*:***********::**:.::****.*::**. ** :* ::*:* *::::*..:*:: . **: :. * .***.*** *:***:***:*: *. :* :**.*..* : * * .::* . *: * : *: : :. : : ::. . :** . . . ", "identical_positions": 230, "similar_positions": 347, "identity": "14.24%" }, { "cls_id": "homologset.agr.MGI:1889509", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9EST1-1", "uniprot_id": "GSDMA_MOUSE", "id": "Q9EST1-1", "name": "Gasdermin-A", "aln": "MTMFENVTRALARQLNPRGDLTPLDSLIDFKRFHPFCLVLRKRKSTLFWGARYVHTDYTLLDVLEPGSSPSDPTDSGNFSFKNMLDARVEGDVDVPKTVKVKGTAGLSRSSTLEVQTLSVAPTALENLHKERKLSADHPFLKEMRERGENLYVVMEVVETLQEVTLERAGKAEGCFSLPFFAPLGLQGSVNHKEAVTIPKGCVLAYRVRQLMVNGKDEWGIPHICNDSMQTFPPGEKPGEGKFILIQASDVGEMHEDFKTLKEEVQRETQEVEKLSPVGRSSLLTSLSHLLGKKKELQDLEQTLEGALDKGHEVTLEALPKDVLLSKDAMDAILYFLGALTVLSEAQQKLLVKSLEKKILPVQLKLVESTMEKNFLQDKEGVFPLQPDLLSSLGEEELILTEALVGLSGLEVQRSGPQYTWDPDTLPHLCALYAGLSLLQLLSKNS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D3ZA32-1", "uniprot_id": "D3ZA32_RAT", "id": "D3ZA32-1", "name": "", "aln": "MTMFENVTRALARQLNPRGDLTPLDSLIDFKCFHPFCLVLRKRKSTLFWGARYVRTDYTLLDLLEPGNTPSDPTDGGNFSFKNMLDARVEGDVDVPKTVKVKGTAGLSQSSTLEVQTLSVAPKALESLHKERKLSADHPFLKEMWERGENLYVVMEVVETVQEVTLERAGKAEGCFSLPFFAPLGLQGSLNHKEAVTIPKGCVLAYRVRQLMVNGKDEWDIPHVYNDSMQTFPPGEKPGEGKFILIQASDVGEMHDDFKTLKEEVRRETREIEKLSQVGRSSLLTSLRHLLGKKKELQDLEHTLEGALDKGHEVTLEALPKDVLLSKDAMDAILYFLGALTVLSEAQQKLLVKSLEKEILPLQLKLVESTLEQNFLQDKEGVFPLRPDLLSSLGEEELTLTEALVGLSGLEVQRSGPQYTWDPDTLPHLCALYAGLSLLQLLSMGS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q96QA5-1", "uniprot_id": "GSDMA_HUMAN", "id": "Q96QA5-1", "name": "Gasdermin-A", "aln": "MTMFENVTRALARQLNPRGDLTPLDSLIDFKRFHPFCLVLRKRKSTLFWGARYVRTDYTLLDVLEPGSSPSDPTDTGNFGFKNMLDTRVEGDVDVPKTVKVKGTAGLSQNSTLEVQTLSVAPKALETVQ-ERKLAADHPFLKEMQDQGENLYVVMEVVETVQEVTLERAGKAEACFSLPFFAPLGLQGSINHKEAVTIPKGCVLAFRVRQLMVKGKDEWDIPHICNDNMQTFPPGEKSGEEKVILIQASDVGDVHEGFRTLKEEVQRETQQVEKLSRVGQSSLLSSLSKLLGKKKELQDLELALEGALDKGHEVTLEALPKDVLLSKEAVGAILYFVGALTELSEAQQKLLVKSMEKKILPVQLKLVESTMEQNFLLDKEGVFPLQPELLSSLGDEELTLTEALVGLSGLEVQRSGPQYMWDPDTLPRLCALYAGLSLLQQLTKAS", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "******************************* **********************:*******:****.:****** ***.******:*********************:.************.***.:: ****:********* ::*************:************.***************:***************:*******:*****.***: **.*********.** *.*********::*:.*:******:***:::**** **:****:** :************ :************************:*:.*****:**** ************:**:***:********:*:*** ********:*:******:*** ******************** *******:************ *: *", "identical_positions": 378, "similar_positions": 52, "identity": "84.75%" }, { "cls_id": "homologset.agr.MGI:1889510", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q5BJM7-1", "uniprot_id": "C42S1_RAT", "id": "Q5BJM7-1", "name": "CDC42 small effector protein 1", "aln": "---MSEFWHK-LGCCVVEKPQPKKR---RRRIDRTMIGEPMNFVHLTHIGSGEMGAGDGLAMTGAVQEQMRSKGN-RDRPWSNSR-AL-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9NRR8-1", "uniprot_id": "C42S1_HUMAN", "id": "Q9NRR8-1", "name": "CDC42 small effector protein 1", "aln": "---MSEFWHK-LGCCVVEKPQPKKK---RRRIDRTMIGEPMNFVHLTHIGSGEMGAGDGLAMTGAVQEQMRSKGN-RDRPWSNSR-GL-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8BHL7-1", "uniprot_id": "C42S1_MOUSE", "id": "Q8BHL7-1", "name": "CDC42 small effector protein 1", "aln": "---MSEFWHK-LGCCVVEKPQPKKK---RRRIDRTMIGEPMNFVHLTHIGSGEMGAGDGLAMTGAVQEQMRSKGNHRDRPWSNSR-AL-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6TEL3-1", "uniprot_id": "C42S1_DANRE", "id": "Q6TEL3-1", "name": "CDC42 small effector protein 1", "aln": "---MSAFWHK-IGCCVVAKPPPKKK---RRRIDRSMIGEPTNFVHLTHIGSGEM--ADGMQPSGPIKEQMRSK-----VPHANGRNSLL", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VNE7-1", "uniprot_id": "C42ES_DROME", "id": "Q9VNE7-1", "name": "CDC42 small effector protein homolog", "aln": "MASTGEIWLQWFSCCFQQQRSPSRRPHQRLRIDRSMIGNPTNFVHTGHIGSADVELSANR--LNAISTQMQSKGG-YETNSIHSLHAC-", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . :* : :.**. : *.:: * ****:***:* **** ****.:: . . ..:. **:** :. . ", "identical_positions": 25, "similar_positions": 25, "identity": "28.09%" }, { "cls_id": "homologset.agr.MGI:1889549", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q02805-1", "uniprot_id": "ROD1_YEAST", "id": "Q02805-1", "name": "Protein ROD1", "aln": "-------------------------------------------------------MFSSSSRPSKEPLLFDIRLRNLDNDVLLIKGPPD---EASSVLLSGT------------IVLSITEPIQIKSLALRLFGRLRLNIPT-----------------------------VLQTVHGPHKR--------------YSKFERNIYSHFWDD--------------------FNIKSYFQNLYDNHNNGKITISSKSSTNLAALPKRKRALSTAS--------------------------------LISSNGQTSASKNY------------------------------HTLVKGNYEFPFSAIIPG--SLVESVEGLPNAAVTYALEATI------ERPK-QPDLICKKHLRVIRTLAID------------------------------------------AVELSETVSVDNSWPEKVDYTISIPTKA--IAIGSSTMINILIVPILKG-----------------LKLGPVRISLVENSQYCGS------------------------------YGGVINQERMVAKLKLKDPLKHVAQIKKKRSLNEAADEGVDTDTGEFQDK-WEVRALLNIPASLTKCSQDCRILSNIKVRHKIKFTISLLNPDG-HI------------------------SELRAALPVQLFISPFVPVNVKTSDVIERTLKTFGPSYQVTSQHDNSFSSKNFVDDSEEDVIFQRSASALQLSSMPTIVSGSTLNINSTDAEATAVADTTMVTSLMVPPNYGNHVYDRVYGEVTNEDETSASASSSA---VESQAIHNIQNLYISDSNNSNNPILAPNPQIKIEDDSLNNCDSRGDSVNNSNLN------------LVNSNLTISEN-----WNNNSPSANRYNNIINAG-------------LNSPSLTPSFAHLSRRNSYSRQTSS--TSLKNDLELTDLSRVPSYDKAMKSDMIGEDLPPAYPEEELGVQENKKIELERPQILHHKSTSSLLPLPGSSKSSNNL------------KRSSSRTHLSHSPLPRNNSGSSVSLQQLARNN---------------TDSSFNLNLSFTSAKSSTGSRHFPFNMTTSFTSN------SSSKNNSHFDKTDSTSDANKPREEENYTSATHNRRSRSSSVRS------NNSNSPLRQGTGSFANLMEMFTK----RDRS--------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P43602-1", "uniprot_id": "ROG3_YEAST", "id": "P43602-1", "name": "Protein ROG3", "aln": "------------------------------------------------------MGFSSGKSTKKKPLLFDIRLKNVDNDVILLKGPPN---EAPSVLLSGC------------IVLSINEPMQIKSISLRLYGKIQIDVPLERP-----------------------QDASSSSLSSSPPK--------------IRKYNKVFYNYAWDN--------------------VNLKEYLSGLRGQSG---LAGSSSSSN---ILGTRQRAQSTSS--------------------------------LKSLKGSSSPSS--------------------------------CTLDKGNYDFPFSAILPG--SLPESVESLPNCFVTYSMESVI------ERSKNYSDLICRKNIRVLRTISPA------------------------------------------AVELSETVCVDNSWPDKVDYSISVPNKA--VAIGSATPINISIVPLSKG-----------------LKLGSIKVVLFENYQYCDP------------------------------FPPVISENRQVTELNLEDPLNESSGEFNGN--GCFVNNPFFQPDHSFQDK-WEIDTILQIPNSLSNCVQDCDVRSNIKVRHKLKFFIILINPDG-HK------------------------SELRASLPIQLFISPFVALSIKP-----LSSSNLYSLFSTTNQKD-----ENSSQEEEEEYLFSRSASVTGLELLADMRSGGSVPT---------------ISDLMTPPNYEMHVYDRLYSGSFTRTAVETSGTCTP---LGSECST------VEDQQQDLEDLRIRLTKIRNQRDNLGLPPSASSAAASRSLSP-----------LLNVPAPEDGT-----ERILPQSALGPNSGSVPG-------------VHS-NVSPVLLSRSPAPSVSAHEVLPVPSGLNYPETQNLNKVPSYGKAMKYDIIGEDLPPSYPCAIQNVQPRK------PSRVHSRNSSTTL--------------------------SSSIPTSFHSSSFMSSTASPISIINGSRS-------------------------------SSSGVSLNTLNELTSKTSN------NPS----------------------------------SNSMK----------RSPTRRRATSLAGFMGGFLS----KGNKR-------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P47029-1", "uniprot_id": "ALY2_YEAST", "id": "P47029-1", "name": "Arrestin-related trafficking adapter 3", "aln": "-------------------------------------MPMDQSISSPLFPMEKDIDIPLDATPLAQSSSLQLFIHLAEPVVFLQGFDPQ-KTEYPSVVLRGC------------LVVRILKPTKLKSISLSFKGYSRTEWPEGIPPKRQEFVEIKDIVDHTWALYPPTEQKSKKKMDASAPNESNN----AANNFLTKESGASLYRTLSDNE----------TITSRKNSISGLSSLNLSPLGAPGNSSVNVKDRESRQRSRSSSVTSSNGPSRNLSPINLLKRATSPSVSHHNYKPTTTSIFSDLLNNTFTHNDAASHHGHHIPTSSNHLAMTSNNFTS----GSGGEFFVFQPGDYIYAFEELIPQ--AYPESIKADFGFVEYFLFASIE------RPGAFKSNISARQVVNIVRTQAHN------------------------------------------SVEESEPIIISRDWENQLYYDIVIASKD--IILDAFLPITFKFAPLDK------------------VTLHRIRIYVTETMEYYCR---------------------------EKKVHRMEPTKKFLLTEQKGPKLPNLPNDANLSKAKNMGNLLQDPKNGDLVNKEYEYQIFIPSRFNNHQQLHPDTSYENIKANHWIKICLRLSRVVDNKR------------------------KHYEISIDSPIHVLHRLCSHANT------LLPSYDGHPASFPKETDSSISSILESSDDNINLYHNSNIFFPKEVLSSPVLSPNVQP----------------LDILIP-HLPSTSLTRNSRQFNRN---SKSHPSDN---TIFNSAKLKSNIYQPESLQRELASPQAIPLSPITSPMSN----MEVPPPDFDFSSDFISDAASGTTTTEVSSSESSI-----LPRDPPSYKDTVLHDNNQKRRPNSKHPTPPSLKASHPNKNSDKNSSETLNK-KESMSKIEENKHKRETTPKKRENRDVKSLSTPQREESKDSTSTGNQSNEKNRKRVLSLSSSLHSSPNNSGFAHSALGNLSNESLRSLNRRESVQDNLPSTIRHDNPFFTDLNQVLIEDELKNHDKNELNRHSTNTSSTPASARSSFDYSGINISKDKLNMEPLLSKTETLTNKVNEDSFLRPNDSYVDLLEPSVDTTIDITAPYARNSSAWHPLQNDNDNNQFSPLLGSNENFLNAANAQNSAESDHNNDIFTQGSGLTESSKNSDSEERFISRLSSPEKVLINTLDNESGLQSINESTL", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P36117-1", "uniprot_id": "ALY1_YEAST", "id": "P36117-1", "name": "Arrestin-related trafficking adapter 6", "aln": "----------------------------------MLQFNTENDTVAPVFPMEQDINAAPDAVPLVQTTTLQVFVKLAEPIVFLKGFETNGLSEIAPSILRGS------------LIVRVLKPNKLKSISITFKGISRTEWPEGIPPKREEFSDVETVVNHTWPFYQADDGMNSFTLEHHSSNNSSNRPSMSDEDYLLEKSGASVYIPPTAE-------------PPKDNSNLSLDAYERNSLSSDNLSNKPVSSDVSHDDSKLLAIQKTPLPSS--------SRRGSVPANFHGNSLSPHTFISDLFTKTFSNSGATPSP----EQEDNYLTPSKD----------SKEVFIFRPGDYIYTFEQPISQ--SYPESIKANFGSVEYKLSIDIE------RFGAFKSTIHTQLPIKVVRLPSDG------------------------------------------SVEETEAIAISKDWKDLLHYDVVIFSKE--IVLNAFLPIDFHFAPLDK------------------VTLHRIRIYLTESMEYTCNSN-----------------------GNHEKARRLEPTKKFLLAEHNGPKLPHIPAGSNPLKAKNRGNILLDEKSGDLVNKDFQFEVFVPSKFTNSIRLHPDTNYDKIKAHHWIKICLRLSKKYGDNR------------------------KHFEISIDSPIHILNQLCSHANT------LLPSYESHFQYCDEDGNFAP----AADQQNYASHHDSNIFFPKEVLSSPVLSPNVQK----------------MNIRIPSDLPVVRNRAESVKKSKSDNTSKKNDQSS---NVFASKQLVANIYKPNQIPRELTSPQALPLSPITSPILNYQPLSNSPPPDFDFD------------LAKRGAADSHA-----IPVDPPSYFDVLKADG---------------IELPYYDTSSSKIPELKLNKSRETLASIEEDSFNGWSQIDDLSDEDDNDGDIASGFNFKLSTSAPSENVNSHTPILQSLNMSLDGRKKNRASLHATS-------------------VLPSTIRQNNQHFNDINQMLGSSDEDAFPKS-----------------QSLNFN---------KKLPILKINDNVIQSNSN------SNNRVDNPEDTVDSSVDITAFYDPRMSSDSKFDWEVSKNHVDP----------AAYSVNVASENRVLDDFKK--AFREKRK-------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "Q9I7K8-1", "uniprot_id": "Q9I7K8_DROME", "id": "Q9I7K8-1", "name": "Arrestin C-terminal-like domain-containing protein", "aln": "------------------------------------------------------------------MVICEIEFCNNSQGIFYAG-----------QLISGQ------------VVIKTEKEKSVKAVILNIKGYAETHWADTEHDPDDQSNGE---------------------------------------------------------------------------SFNGHVDYLATRAYLHGS------SSSIE--------------------------------------------------------------------------------------------VLIEPGTSSYRFACQLPI--TCPSSFEGTLGRIRYLVNVRFV------RPWKFDLNFNRCFTVIKVMDLNSES----------------------------------LMLRVPSQVESQRTFCCFPCRSSPLSMRLSVPQSG--FVPGQIVPVEVMVSNDSG------------------VAVEDITVKLTMVVIYYSQ------------------------------------------------PPSA-DTNKDRFEMVLKTGGGVSTKCRQQFTFDLKVPPTPPTCFNL---------CSIIQIGYQVEAEARVKGCHG----------------------------GQSLHMPITIGSVPLT-KQLQKE------------PRTWGEVLPPQQLDAKALILIGSEQNGEALGSPNPWAADP----------------------------SIAPPSYAEAKHISPDPHKFSKSKKKSQKRGVKGSQERKAETIVFSPLYAVFDLSNQVDEMTLRANEPKTDG-----GYVNEGVEKSTWL--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "A8JQV1-1", "uniprot_id": "A8JQV1_DROME", "id": "A8JQV1-1", "name": "Arrestin C-terminal-like domain-containing protein", "aln": "-----------------------------------------------------------------MGIICQILFHNNTQGVFYAG-----------QMVAGQ------------VTLSTDKAIQIKAIRLKLKGYAETHWTESKTDSNNKSTSE---------------------------------------------------------------------------SYNGFEKYLSSKVYLLGS------EISPE--------------------------------------------------------------------------------------------MALEPGTRSYNFACPIPI--NCPSSFEGTHGRIRYMVDVNII------QPWKYDSIFSRAFTVIQVMDINTYN----------------------------------SVSQVPVQAKTEKTFGVWPFRSDPLTLELNLPQTG--FVPGQTVPANVLIGNESK------------------IRVHEVKVGLSMMITYYSD------------------------------------------------LSSG-SKCERKSVAKLKADG-VLRNSRKMYDFQLMIPSTPPSCFHL---------CRIIKIGYQIEVVAKVKGMHI----------------------------NGTLIMPVTICGVPISPSAVQYT------------PQSSGPEAPEQ----RALTLIEGEGAFAPAAPPYPWSEGS----------------------------TLSPPNYAEAMHSHSDSEKQSESGNAQEKS--------------YKPLYPVFDLSTSTVEKSKEAALDKEE-------------KK------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9I7L0-1", "uniprot_id": "Q9I7L0_DROME", "id": "Q9I7L0-1", "name": "Arrestin C-terminal-like domain-containing protein", "aln": "-----------------------------------------------------------------MTVTCEIDFDNNPHGTYFGG-----------EVLTGR------------VTLKLDKMKLVKAITLNITGYAETRWIERVT-TNRRRRRR---------------------------------------------------------------------------TFCGREDYIASKTFLVGS------NLSSQ--------------------------------------------------------------------------------------------VSIEAGIHTYNFVCLIPT--ECPSSFEGSHGRVRYMATVTLV------RPWKFDQSYTRCFTVLKVMDLNFDS----------------------------------PLLRVPAHSETSKTYCCWPCRSDPLALQLTVPQTG--FVPGQNVPLSVLVTNDSH------------------IPVEQLLISFVMLVTYHSK------------------------------------------------PPSMPNTTSERLVVNTFKGDAVQRNCKKLFSYEIRVPATPPTCFNL---------CGIIQIAYQVEVEARVKGCHN----------------------------NEVVTIPLTIGSVPLA-QHVPIQ------------PRGFVPQLNVN--------ELAVEEVATAPNSSSPWSVDA----------------------------SIPPPNYQEAVHMRSTAATRSDDLDDPEPVPPN---TLSLDGGAYKPLYPVFDIPSPSAPPPTDYTQNYMAERAFVNPAMDVDKDKGTWL--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9I7L1-1", "uniprot_id": "Q9I7L1_DROME", "id": "Q9I7L1-1", "name": "Arrestin C-terminal-like domain-containing protein", "aln": "-----------------------------------------------------------------MVVTCEISFDNNKHGTFYAG-----------QLVKGC------------ATLKCDRSKEVQAVLLKVVGYSITKWSEKSLGSTKL--------------------------------------------------------------------------------YVGREDYLSSNTYLVGSEQNNTHNNTHR--------------------------------------------------------------------------------------------LTIEAGVHSYNFTCQLPY--QCPSSFEGRHGCIRYIVKVLLI------RPWKFDQAYTKGFTVLKMLDLNFDT----------------------------------PQLKSAAHSEGYRTFCCGPCKTDPLKLELHLPQAG--YVPGQKIPVTIVVVNNTA------------------VAVSEIRLSLVMLVRYYSV------------------------------------------------SPEH--SRVERLIISRAKGESVLKQCTRSQTIDLPVPSTPPTCVEL---------SNLIQIAYQLEVEALVKSLRE----------------------------QQLMVMPVTVGTIPLAVSGIVVQQ----------PPRRSAHYEGPDS-RRNPPDELPMVTALESLPSDLASSAAD----------------------------SALP-NYEESRHTQRGNINEEELHAFGSNE--------------FAPLYPVYSIPSPTPVLTANARNAGFVN---------QSFVK------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VI53-1", "uniprot_id": "Q9VI53_DROME", "id": "Q9VI53-1", "name": "Arrestin C-terminal-like domain-containing protein", "aln": "----------------------------------------------------------------MGLKGCELQLDN-PWNTYYAG-----------QTVNGQ------------VKFTFDSPKKVRGIIIRFLGEANTEWSEEKSVTTSEGKTENE-----------------------------------------------------------------------VTQLKGHEEYFKIQYYLLGG------KNSSE--------------------------------------------------------------------------------------------TELPPGTHTYPFTCALPP--NLPSSFEGEFGHVRYTIKVTLD------RPWKFDQDMKMAFTVIAPVDLNLN-----------------------------------PRVKEPFKLELEKSFCCFCCRSGPLAVITNIPQTG--FVSGQVLPITCEVDNTSN------------------VNLTAVKFELRKLVTFHTN------------------------------------------------QPRS-EKRESKVIIANLSVGPVNGGESRTFTQQMEIPALPPTNLLN---------CGIIALDYDLHVECEVSGPHR----------------------------NLTGKVPITLGTIPLAGVRPPTQF----------TDAPSAVQSEDPSLAPTQPVSPASPPGGDGVGGALGWNVADSTGGGS-------------------LYPNIPPPQFVETQYRAPTIAGRDDSEHTQMIG-----------DGAFAPRYPTFQFNNATAPPASQ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q8BG60-1", "uniprot_id": "TXNIP_MOUSE", "id": "Q8BG60-1", "name": "Thioredoxin-interacting protein", "aln": "------------------------------------------------------------MVMFKKIKSFEVVFNDPEK-VYGSG-----------EKVAGR------------VIVEVCEVTRVKAVRILACGVAKVLWMQGSQ------------------------------------------------------------------------------------QCKQTLDYLRYEDTLLLEEQPTAGENEMV--------------------------------------------------------------------------------------------IMRPGNKYEYKFGFELPQ-GPLGTSFKGKYGCVDYWVKAFLD------RPSQPTQEAKKNFEVMDLVDVNTP------------------------------------DLMAPVSAKKEKKVSCMFIPDGRVSVSARIDRKG--FCEGDDISIHADFEN----------------------TCSRIVVPKAAIVARHTY------------------------------------------------LANGQTKVFTQKLSSVRGNHIISGTCASWRGKSLRVQKIRPSILG----------CNILKVEYSLLIYVSVPGSK-----------------------------KVILDLPLVIGSR--SGLSSRTS------------SMASRTSSEMSWIDLNIPDTPEAPPCYMDIIPEDHRLESP----------------------------TTPLLDDVDDSQDSPIFMYAPEFQFMPP------------------PTYTEVDPCVLNNNNNNNNVQ-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q5M7W1-1", "uniprot_id": "TXNIP_RAT", "id": "Q5M7W1-1", "name": "Thioredoxin-interacting protein", "aln": "------------------------------------------------------------MVMFKKIKSFEVVFNDPEK-VYGSG-----------EKVAGR------------VTVEVCEVTRVKAVRILACGVAKVLWMQGSQ------------------------------------------------------------------------------------QCKQTLDYLRYEDTLLLEDQPT-GENEMV--------------------------------------------------------------------------------------------IMRPGNKYEYKFGFELPQ-GPLGTSFKGKYGCVDYWVKAFLD------RPSQPTQEAKKNFEVMDLVDVNTP------------------------------------DLMAPVSAKKEKKVSCMFIPDGRVSVSARIDRKG--FCEGDDISIHADFEN----------------------TCSRIVVPKAAIVARHTY------------------------------------------------LANGQTKVLTQKLSSVRGNHIISGTCASWRGKSLRVQKIRPSILG----------CNILRVEYSLLIYVSVPGSK-----------------------------KVILDLPLVIGSR--SGLSSRTS------------SMASRTSSEMSWIDLNIPDTPEAPPCYMDVIPEDHRLESP----------------------------TTPLLDDVDDSQDSPIFMYAPEFQFMPP------------------PTYTEVDPCVLNNNNNN--VQ-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9H3M7-1", "uniprot_id": "TXNIP_HUMAN", "id": "Q9H3M7-1", "name": "Thioredoxin-interacting protein", "aln": "------------------------------------------------------------MVMFKKIKSFEVVFNDPEK-VYGSG-----------EKVAGR------------VIVEVCEVTRVKAVRILACGVAKVLWMQGSQ------------------------------------------------------------------------------------QCKQTSEYLRYEDTLLLEDQPT-GENEMV--------------------------------------------------------------------------------------------IMRPGNKYEYKFGFELPQ-GPLGTSFKGKYGCVDYWVKAFLD------RPSQPTQETKKNFEVVDLVDVNTP------------------------------------DLMAPVSAKKEKKVSCMFIPDGRVSVSARIDRKG--FCEGDEISIHADFEN----------------------TCSRIVVPKAAIVARHTY------------------------------------------------LANGQTKVLTQKLSSVRGNHIISGTCASWRGKSLRVQKIRPSILG----------CNILRVEYSLLIYVSVPGSK-----------------------------KVILDLPLVIGSR--SGLSSRTS------------SMASRTSSEMSWVDLNIPDTPEAPPCYMDVIPEDHRLESP----------------------------TTPLLDDMDGSQDSPIFMYAPEFKFMPP------------------PTYTEVDPCILNNNVQ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AC58HG91-1", "uniprot_id": "A0AC58HG91_DANRE", "id": "A0AC58HG91-1", "name": "Thioredoxin-interacting protein", "aln": "-----------------------------------------------------------MGVLTKKPKAFEVQMSDPNKIAYSGG-----------DKVAGR------------VIVEVAELLKVSAVKLFGVGCAKVNYKKGKL------------------------------------------------------------------------------------HCSEEIEYLKYEEILHLDHHSTTDDEGSI--------------------------------------------------------------------------------------------TLRPGNRYEFMFGFELPQSGCLVSSYEGKFGSVQYYVRAVME------KSSQTFAECKRYFEVVEPIDVNTQ------------------------------------ELMAPVKGSKQKKVTCMFIPDGSVSIVASIGRKG--YCEGEDICIDAQFEN----------------------TSSRIVIPKAAIIAKHIY------------------------------------------------LANGRTKVFEEKLTSVRGNHIISGMGDIWQGRVLRVPKLKPTILG----------CDIIHVDYSLRIYLHIPGSE-----------------------------KLILELPLVIGTIPYNGMNSRTS------------SMSSQESASSTCVSL-----PSSPPSYSNIS---NRMDSS----------------------------FIPLLDDYDE-DDSPIFMQI-HHPLPPP------------------PLYTEQHI--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VI00-1", "uniprot_id": "Q9VI00_DROME", "id": "Q9VI00-1", "name": "Arrestin C-terminal-like domain-containing protein", "aln": "-----------------------------------------------------------------MPSSCSFELDRREP-IYYSG-----------ETVNGR------------AILTTTSEKSVNEVYILFEGEAKVRWDERRTRTRGGKTEHYT------------------------------------------------------------------------EYFRGKQQYLYTRTSVFGS-------------------------------------------------------------------------------------------------------GNLPPGTHTYNFCIPLPL--ECPSSVVAQYGKIFYEVSVVID------RQWRFNNVFKQPLTVIQTYNLNMS-----------------------------------PQLLMPLVREDIKHFCCWPCSSGPVLSTLTIPFGG--YAPGQKIRFTLEIDNQSSG-----------------YDLNGIELKLKQIYKFQAQ------------------------------------------------TPHHKTREKEHSLNKSCQQERVLRLSKKKIEGTLAIPAVPPSSRTEG----------IISVSYQVILTISTGDCHV----------------------------DSDFEVPIVIGTIPLIQSAENPAS-----------AAQWIPETPDTPAGAAADLPPSYDKCKPPTFEEATNFGER-----------------------------FIDIDQDEHNRTDDFIPRYPMYTNFAMPSAPP-----------QPPEEFATNQPVPVLSLPHDPTAPLVGQNNTDRPTQSYGWNTNS----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "A0A0B4KGD9-1", "uniprot_id": "A0A0B4KGD9_DROME", "id": "A0A0B4KGD9-1", "name": "Arrestin C-terminal-like domain-containing protein", "aln": "-----------------------------------------------------------------MPIECLISFDNNPQGVYYAG-----------QELSGV------------VDLSVDATKRIKGIHVTVSGYAKIRWIKKGYPRDSER-----------------------------------------------------------------------------AMCRAYRSYLSSRSYVLGS----CANNSS---------------------------------------------------------------------------------------------IDWPAGEYSYTFHVILPD--NLPTSFDGKYGQIHYEIITTIE------RAARHPKVFKLPFTVIQPLDLNAD-----------------------------------AIYRVPLEILDRKRFWSFCCPTGPLTVKFSTPYCG--YAPGQKIHFVLYINNESS------------------IDIIECEVKLKQEVSYESH-------------------------------------------------DPQHEYRYDKHLIARKQFGNVLRWSRKVYRGYLDLPSIPPTSVKP---------TCPISVNYSIKIIVNPTEFHW----------------------------KLKLKIPLTIGSIPIMDGPEALLR---------FNRQQQQHQVVSQNLQMSTQQRQRDRDRDRDMNVDRERDRDRDRDRISASVQ----------------QRRISSINNNNNNHGRLVGGLLPTNSNMNMITNVS------PTPTSSTPSSTPTTAALRPTAMPAILVTSDSDNPPDYIPMMPPSYEDAMALSEKFSDDTEFLTNVSMSSILSAQ-----ADVTTSEP----------------------------------FKPRYPVYYDYETPTIPPETLYDESSSRLRLTLSCQDSAAPETDEDLAPNTRGGEPPSCEKK--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P53179-1", "uniprot_id": "PALF_YEAST", "id": "P53179-1", "name": "pH-response regulator protein palF/RIM8", "aln": "---------------------------------MSLLRLWNKESRAPSKIKSHGIVGSYGNSMLAHNNVKQFRIDIDEPHRVWKP----------NESITGE------------AVIDIKRDITNVAIKLSLVCEVRVKTGNSPTSKNKRIEKTLEKS-----------------------------------------------------------------------TFLYGQDYVKTAFSAKEKKPHVDKTTILN---------------------------------------------------------------------------------------------GLSKGEHRFPFRIRIPRGRGMLSSIKFERGSITYFLSCTLESLNNINGLKKPEARCEREFAVIVPLDVSRLPKPKTKTVVLQSASMVQNKKNKSTEDESSSYTQLTQKSTTSNSSSSSVNSKTSPLPNKTVTISVDIPQAG--FMIGEIIPIDVKIDHYKPF-----------------YAPAGLTTTLVRICRVGGAG------------------------------------------------KDDPMETFRKDICQSISPIYINPETLQFQSRVYLKVPLDAFSTLTTVG-------KFFSFQYYIEVMVNLSKKNVVYT-------------------------ESNRIIGTPIGEQNGLGVENNINR-----------IQRKMLRMVNPETLENDSEGYESSIFFKDMVNVEKLKRLRNVTGMS--------------------IETVIGTTRSEQQQSDASIPSQSSITAPQNSPSNLR------DWLAPLNAYDSDDVPVPKYSPNDKVSVPSEDKQELEQKRLQQLESDPPPCDDY-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "Q12502-1", "uniprot_id": "LDB19_YEAST", "id": "Q12502-1", "name": "Protein LDB19", "aln": "---------------------------------------MAFSRLTSTHQSNHNGYSNSNKKGQSLPLTLSIDVESPPCVLYGSAMESS------GAVLSGL------------FTVTVVDPYSSAEDKSLKNTESNVSTTSKSLKRK-----------------------------------------------------------------------------------STFGSALSSRLSSLSASTSNISPSTSS--------------------------------------------------------------------------------------------TSISHSPTPANLRIMAGYTKITITSVTLSLVQKIHFHKPFVPN----ISSMQTCMNCKTKITNMKSWEIQSN-------------------------------------TQDLSVGSHSYPFSYLIPGSVPCSSSLGATAET--QVKYELIAVVTYIDPHRNS-----------------FSSGHSTPRKEGSSSKKRLLQ-----------------------LAMP-------------------IAVTRSIPRGPDKNSLRVFPPTELTAAAVLPNVVYPKSTFPLEMKLDGVSSGDRRWRMRKLSWRIEETTRVKAHACPVH------------------------KHELRQLEEQVKIKESEKSKKPRSHIKR------YGELGPQIRVAVNSLENMPSQRLPGEPGREQAPNSSGPASTGNVG-----------------------LDDENPVNEDEEDQPGSEFIHPSDDALRQELLMQQ---------QRARQQQLQQELKNNSSLFTEEVRIISKGEMKSGWKTDFDNNGKIELVTEIDCMGLNSGVSNPVMHASTLQ-----TPSTGNKKPSINVACDIQDPNLGLYVSHILAVEIVVAEETLQYANGQPIRKPNSKNKKETNNNTMNVHNPDQRLAELSPIFANRNTPKVRRMGPEDITPVNSNKSNHSTNKEKASNGASNSNIVSVPTGAARVLRMQFRLTVTERSGLGISWDEEVPPIYQDVELLSPPCYELSINNGIKNKLYSTMSTPVRSEDDFVGGSDEDIGNYESQGLEPGPNVQEVTITQNKLTIPPTAHHYQPASSSQRSLTTVQSPPLESVVSVQGSVPFRGHVLTPHSTRDIRIQNFSDFLDSNRITQ-------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P38167-1", "uniprot_id": "ECM21_YEAST", "id": "P38167-1", "name": "Protein ECM21", "aln": "-----MPFITSRPVAKNSSHSLSETDLNQSKGQPFQPSPTKKLGSMQQRRRSSTIRHALSSLLGGANVHSPAVLNNTTKGGNNNGNIRS---SNTDAQLLGK------------KQNKQPPPNARRHSTTAIQGSISDSATTTPRSSTSDTNRRTSGRLSVDQEPRISGGRYSQIEEDSTVLDFDDDHNSSAVVSSDLSSTSLTRLANSKKFNEQFLIEYLTARGLLGPKTVLSNEYLKISISTSGESVFLPTISSNDDEYLSRLNGLNDGTDDAEADFFMDG--------------IDQQEGNTPSLATTAAATESGGSINENRDTLLRENNSGDHPGS----GSELNTRSVEIDSSMVSYSIAVIVSVKKPTRFTDMQLELCSRVKVFWN------TGVPPTKTFNEEFYNAASMKWNLNDE--------------------------------NFDLFVPLSISPDDQMIENNSNDRQMRLFKNIPTEE--RLYLDKTKTKASLLNAIDVNKTHLYQPGDYVFLVPVVFSNHIPETIYLPSARVSYRL-----------------------RLATKAINRKGFYRQDSNSPQPIVSPDSSSSLSSTTSSLKLTETESAQAHRRISNTLFSKVKNHLHMSSHQLKNEESGEEDIFAEYPIKVIRTPPPVAVSTANKPIYINRVWTDSLSYEISFAQKYVSLNSEVPIKIKLAPICKNVCVKRIHVSITERVTFVSKGYEYEYDQTDPVAKDPYNPYYLDFASKRRKERSVSLFEIRTKEKGTRALR---------------EEIVENSFNDNLLSYSPFDDDSDSKGNPKERLGIT-EPIIIETKLKFPKYEDLDKRTAKIIPPYGIDAYTSIPNPEHAVANGPSHRRPSVIGFLSGHKGSKSHEENEKPVYDPK-----FHQTIIKSNSGLPVKTHTRLNTPKRGLYLDSLHFSNVYCRHKLEIMLRISKPDPECPSKLRHYEVLIDTPIFLVSEQCNSGNMELPTYDMATMEGKGNQVPLSMNSDFFGNTCPPPPTFEEAISVPASPIVSPMGSPNIMASYDPDLLSIQQLNLSRTTSVSGPSGYSDDAGVPNVNRNSISNANAMNGSISNSAFVSGNSGQGVARARATSVNDRSRFNNLDKLLSTPSPVNRSHNSSPTNGLSQANGTVRIPNATTENSKDKQNEFFKKGYTLANVKDDEEQEGIVSSSSADSLLSHGNEPPRYDEIVPLMSDEE-----------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "Q12734-1", "uniprot_id": "CSR2_YEAST", "id": "Q12734-1", "name": "Transcription factor CSR2", "aln": "MQSTVPIAIASNGNKRDVVQNVSAGDEGDILQRLARNREMISTSLSPQKSSGFSGRRRSSSVRDALSSFFGTGNSPTSSMDDYSNLMNRNYSTASTAMCRGNSFPSDVGTKAYNITGSYQPDRHRNSVPYTTIDQLHTRQDTGLRRESDPVAAKQISSNNDIVRSFITHHASNSTMFINRVLSDYLADRGFIKQTPLYNKKSVLEISIATSAES----------VFLPTTKSDETEYLSLIHGSLNQARTQPVGSTNTAESDFLPSCPTMDTLNENNDLSLFPLHTQRTSPSNTARTGNAMDTSNSDRASPASNNNTTDADSFVASGNNNPMNNNNSPARNRHPNSHSRSLPNAWNSQMPSFSFALIFSLNKSTTLSDIKVELTSNVRVVWFN------GLPPTKNVNEECYNIGSLDWTLNADN--------------------------------FNLFIPQGAKSPLDIVENHSNNRKLKVLQKLSMRKRRSFSNKAVLRENILNNLNASNSTNKLNAGVYVFTIPIVLASRIPESLYYPSARVSYSLRLATKLKDEHTQLVASRPRSSSISSPQKLRSYSCSDSYEYSQIDDTIEGETYNNDKNSTGKIAFPSSWLKSAKGRLKRNNSNGRSDNNGASSSGLAMQHDSEDTINLQYPLNLVRTPPEISVTTANKPLYINKVWENCLSYEISFAQKYVPLNGEIPITIKVAPLVKSLSVKRIRVSCREKISYRSKDYQYDFDQLDPLASDPCNPYHMRYLVRKKKDRSLPLFEVASKCTSGPS---------------IREEVVTNTVDDNLLAYTSSKENNKDIPFSESFTVKT--------KLKFPKYCEVDATKAASLPPYGIDLFDPIKDPTQSENTSNNGNVLGFLVGRPNRASKTVHKIPQDKNHNEVNDTNGNSNTSLQTSSNVPIQHYTRLNKPRRGLYLDSMHFKNIQCSHKLEIVLRVSKTDSGSSKIIRHYEVIVDTPIYLISDLCNTSNIDLPTYDMATTESSKVLPPTFEEATSVSASPRSSVSYYPDDISMQQLNLSRSTSLANGYLSTLHPKTTAVSDSSNGAPIRDQQEQQARPLRTEDYALQMGNENNAYSNMDGLLSQDIFEQETAATLFKRDIVTMNFNNNIFTPRYSPRTFTNTDYNYNDNDNNDNDTEGPGPIIHPGPEPPRYDEISS----------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * . . : : : ", "identical_positions": 1, "similar_positions": 5, "identity": "0.08%" }, { "cls_id": "homologset.agr.MGI:1889574", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9ES89-1", "uniprot_id": "EXTL2_MOUSE", "id": "Q9ES89-1", "name": "Exostosin-like 2", "aln": "MMRGCHICKLPGRVMGIRVLRFSLVVILVLLLVAGALTNLLPNIKEDKMLTLRREIKSPSKSALDSFTLIMQTYNRTDLLLRLLNHYQAVPSLHKVIVVWNNVGEKGPEELWNSLGPHPIPVIFKPQTANKMRNRLQVFPEVETNAVLMVDDDTLISAQDLVFAFSIWQQFPDQIIGFVPRKHVSTSSGIYSYGGFELQTPGPGNGDQYSMVLIGASFFNSKYLELFQKQPAAVHALIDETQNCDDIAMNFLVTRHTGKPSGIFVKPINMVNLEKETN-GYSGMWHRAEHFLQRSYCINKLVNIYDGMPLKYSNIMISQFGFPYANHKSKM", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "F7F8T0-1", "uniprot_id": "F7F8T0_RAT", "id": "F7F8T0-1", "name": "Exostosin-like 2", "aln": "TMRGCHICKLPGRVMGIRVLRFSLVIILVLLLVAGALTNLLPNIKEDKMLTVRREIKSQSKSALDSFTLIMQTYNRTDLLLRLLNHYQAVPNLHKVIVVWNNVGEKGPEELWNSLGPHPIPVLFKPQTANRMRNRLQVFPEVETNAVLMVDDDVLISAQDLVFAFSIWQQFPDQIVGFVPRKHVSTSSGIYSYGGFELQTPGLGNGDQYSMVLIGASFFHSKYLDLFQKQPAAVHTLIDETQNCDDIAMNFIVSKHTGKSSGIFVKPINIINLEKETN-GYSGMWHRAEHFLQRSYCLNKLVNIFSGMPLKYSNIMISQFGFPYANHKSKM", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9UBQ6-1", "uniprot_id": "EXTL2_HUMAN", "id": "Q9UBQ6-1", "name": "Exostosin-like 2", "aln": "-MRCCHICKLPGRVMGIRVLRLSLVVILVLLLVAGALTALLPSVKEDKMLMLRREIKSQGKSTMDSFTLIMQTYNRTDLLLKLLNHYQAVPNLHKVIVVWNNIGEKAPDELWNSLGPHPIPVIFKQQTANRMRNRLQVFPELETNAVLMVDDDTLISTPDLVFAFSVWQQFPDQIVGFVPRKHVSTSSGIYSYGSFEMQAPGSGNGDQYSMVLIGASFFNSKYLELFQRQPAAVHALIDDTQNCDDIAMNFIIAKHIGKTSGIFVKPVNMDNLEKETNSGYSGMWHRAEHALQRSYCINKLVNIYDSMPLRYSNIMISQFGFPYANYKRKI", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ** *****************:***:************ ***.:****** :****** .**::*****************:*********.**********:***.*:*************:** ****:**********:***********.***: *******:********:******************.**:*:** ****************:****:***:******:***:***********::::* **.*******:*: ******* *********** ******:******:..***:***************:* *:", "identical_positions": 276, "similar_positions": 42, "identity": "83.38%" }, { "cls_id": "homologset.agr.MGI:1889575", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P55266-1", "uniprot_id": "DSRAD_RAT", "id": "P55266-1", "name": "Double-stranded RNA-specific adenosine deaminase", "aln": "--------------MSQGFRGPTGVFPHQTQP------------CLDPSYEHSKWRYLQPRGSESYLR------------------------------SFQLQQIEFLKGRLPEAPLIGAQTQ--SLPPFLPGHWPRFP---GPPAQGKQPEIWGFPR-SVTLRNQGFHIGPPLPPPHSRG----PPWRG---------------AEGLCSHFQELSISQNPE-----------------------------------QKVLNRLEELGEGKATTAYALARELRTPKKDINRILYSLERKGKLHRGVGKPPLWSLVPLSQACTQPP-------------------------------------------------RAVNSD---KEVPRGEPDLDSEDGDPASDLEGPSELLDMAEIK---EKICDYLFNVSKSSALNLAKNIGLAKARDVNAVLIDLERQGDVYR-EGATPPIWYLTDKKRERLQMKRSTHSGP------AATPAAVSEATQSTSFPTCHPPQSGG--------SSSMATSKRVEN-GQEPVTKYESRHEARPGPVRLRPHAYHNGPSRAGYVASENGPWATDDIPDNLNSIHTAPGEFRAIMEMPSFYSPTLPRCSPYKKLTECQLKNPVSGLLEYAQFTSQTCDFNLIEQSGPSHEPRFKFQVVINGREFPPAEAGSKKVAKQDAAVKAMAILLREAKAKDSGQPEEL----SNCPMEEDPEKPAESQPPSSSATSLFSGKSPVTTLLECMHKLGNSCEFRLLSKEGPAHDPKFQYCVAVGAQTFPSVSAPSKKVAKQMAAEEAMKALQEEAAN-------------SADDQSGGANTDSLD----ESVAPNKIRRIGELVRYLNTNPVGGLLEYARSHGFAAEFKLIDQSGPPHEPKFVYQAKVGGRWFPAVCAHSKKQGKQDAADAALRVLIGESEKAEQLGFAEVTPVTGASLRRTMLLLSRSPDAHPKTLPLTGSTFHDQIAMLSHRCFNALTNSFQPSLLGRKILAAIIMKRDPEDMGVVVSLGTGNRCVKGDSLSLKGETVNDCHAEIISRRGFIRFLYSELMKYNHHTAKNSIFELARGGEKLQIKKTVSFHLYISTAPCGDGAHFDKSCSDRAVESTESRHYPVFENPKQGKLRTKVENGEGTIPVESSDIVPTWDGIRLGERLRTMSCSDKILRWNVLGLQGALLTHFLQPVYLKSVTLGYLFSQGHLTRAICCRVTRDGNAFEDGLRYPFIVNHPKVGRVSVYDSKRQSGKTKETSVNWCLADGYDLEILDGTRGTVDGPGKELSRVSKKNIFLQFKKLCSFRARRDLLQLS-YGEAKKAARDYDLAKNYFKKSLRDMGYGNWISKPQEEK---------------------------NFYLCPVPND--------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q99MU3-1", "uniprot_id": "DSRAD_MOUSE", "id": "Q99MU3-1", "name": "Double-stranded RNA-specific adenosine deaminase", "aln": "--------------MSQGFRGPTGVFPHQTQS------------YLDPSHEHSKWRYPQPQGPESYPR------------------------------SFQLQQIEFLKGRLPEAPLIGIQTQ--SLPPFLPGHWPRFP---GPPAQDRQLEIWEFPR-SVTLRNQGFHIGPPLPPPHSRG----TPWRG---------------ADGLCSHFRELSISQSPE-----------------------------------QKVLNRLEELGEGKATTAHVLARELRIPKRDINRILYSLEKKGKLHRGRGKPPLWSLVPLSQAWTQPP-------------------------------------------------GVVNPDSCIQEFPRGEPGLDSEDGDPASDLEGPSEPLDMAEIK---EKICDYLFNVSNSSALNLAKNIGLTKARDVTSVLIDLERQGDVYR-QGATPPIWYLTDKKRERLQMKRSTHSAP------APTPTAVPEATRSPSFPACHPPPAGA--------SSSVAASKRVEN-GQEPAIKHESRHEARPGPMRLRPHAYHNGPSRAGYVASENGQWATDDIPDNLNSIHTAPGEFRAIMEMPSFYSPTLPRCSPYKKLTECQLKNPVSGLLEYAQFTSQTCDFNLIEQSGPSHEPRFKFQVVINGREFPPAEAGSKKVAKQDAAVKAMAILLREAKAKDSGQPEDL----SHCPMEEDSEKPAEAQAPSSSATSLFSGKSPVTTLLECMHKLGNSCEFRLLSKEGPAHDPKFQYCVAVGAQTFPPVSAPSKKVAKQMAAEEAMKALQEEAAS-------------SADDQSGGANTDSLD----ESMAPNKIRRIGELVRYLNTNPVGGLLEYARSHGFAAEFKLIDQSGPPHEPKFVYQAKVGGRWFPAVCAHSKKQGKQDAADAALRVLIGESEKAEQLGFAEVTPVTGASLRRTMLLLSRSPDAHPKTLPLSGSTFHDQIAMLSHRCFNALTNSFQPSLLGRKILAAIIMKRDPEDMGVVVSLGTGNRCVKGDSLSLKGETVNDCHAEIISRRGFIRFLYSELMKYNHHTAKNSIFELARGGEKLQIKKTVSFHLYISTAPCGDGALFDKSCSDRAVESTESRHYPVFENPKQGKLRTKVENGEGTIPVESSDIVPTWDGIRLGERLRTMSCSDKILRWNVLGLQGALLTHFLQPVYLKSVTLGYLFSQGHLTRAICCRVTRDGKAFEDGLRYPFIVNHPKVGRVSVYDSKRQSGKTKETSVNWCMADGYDLEILDGTRGTVDGPGKELSRVSKKNIFLQFKKLCSFRARRDLLQLS-YGEAKKAARDYDLAKNYFKKSLRDMGYGNWISKPQEEK---------------------------NFYLCPVPND--------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P55265-1", "uniprot_id": "DSRAD_HUMAN", "id": "P55265-1", "name": "Double-stranded RNA-specific adenosine deaminase", "aln": "--------------MNP--RQGYSLSGYYTHP------------FQG--YEHRQLRYQQP-GPGSSPS------------------------------SFLLKQIEFLKGQLPEAPVIGKQTP--SLPPSLPGLRPRFPVLLASSTRGRQVDIRGVPR-GVHLRSQGLQRGFQHPSPRGRS----LPQRG---------------VDCLSSHFQELSIYQDQE-----------------------------------QRILKFLEELGEGKATTAHDLSGKLGTPKKEINRVLYSLAKKGKLQKEAGTPPLWKIAVSTQAWNQHSGVVRPDGHSQGAPNSDPSLEPEDRNSTSVSEDLLEPFIAVSAQAWNQHSGVVRPDSHSQGSPNSDPGLEPEDSNSTSALEDPLEFLDMAEIK---EKICDYLFNVSDSSALNLAKNIGLTKARDINAVLIDMERQGDVYR-QGTTPPIWHLTDKKRERMQIKRNTNSVP------ETAPAAIPETKRNAEFLTCNIPTSNA--------SNNMVTTEKVEN-GQEPVIKLENRQEARPEPARLKPPVHYNGPSKAGYVDFENGQWATDDIPDDLNSIRAAPGEFRAIMEMPSFYSHGLPRCSPYKKLTECQLKNPISGLLEYAQFASQTCEFNMIEQSGPPHEPRFKFQVVINGREFPPAEAGSKKVAKQDAAMKAMTILLEEAKAKDSGKSEES----SHYSTEKESEKTAESQTPTPSATSFFSGKSPVTTLLECMHKLGNSCEFRLLSKEGPAHEPKFQYCVAVGAQTFPSVSAPSKKVAKQMAAEEAMKALHGEATNSM-----------ASDNQPEGMISESLDNL--ESMMPNKVRKIGELVRYLNTNPVGGLLEYARSHGFAAEFKLVDQSGPPHEPKFVYQAKVGGRWFPAVCAHSKKQGKQEAADAALRVLIGENEKAERMGFTEVTPVTGASLRRTMLLLSRSPEAQPKTLPLTGSTFHDQIAMLSHRCFNTLTNSFQPSLLGRKILAAIIMKKDSEDMGVVVSLGTGNRCVKGDSLSLKGETVNDCHAEIISRRGFIRFLYSELMKYNSQTAKDSIFEPAKGGEKLQIKKTVSFHLYISTAPCGDGALFDKSCSDRAMESTESRHYPVFENPKQGKLRTKVENGEGTIPVESSDIVPTWDGIRLGERLRTMSCSDKILRWNVLGLQGALLTHFLQPIYLKSVTLGYLFSQGHLTRAICCRVTRDGSAFEDGLRHPFIVNHPKVGRVSIYDSKRQSGKTKETSVNWCLADGYDLEILDGTRGTVDGPRNELSRVSKKNIFLLFKKLCSFRYRRDLLRLS-YGEAKKAARDYETAKNYFKKGLKDMGYGNWISKPQEEK---------------------------NFYLCPV-----------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1P8J0-1", "uniprot_id": "A0A8M1P8J0_DANRE", "id": "A0A8M1P8J0-1", "name": "", "aln": "MSRGRGGNYKDSQRFSLPFRKGQPQFYSSTTTGQSRGPRVPSPSSLSGSSPHPSFYSSYSSGPGVPPRDHPFPPRHSDPSLWASPQHGSDQISDSNGVSFRQNQVQFLRGQSAQAPQFKAPQPRGSQSSSRGEEVSTEPIQYQTGYRDFKSNSYSFGRRNCYGRGQDNWQGEQNFGPKKRSGWNHPHQKGQYYSNQHYKQFWNARANDLSSGIYNLSFGDRVKRVDTSDTLSCSNSSSKVSSSSSSFRDSLYLTPEIHQQVCAFLTSLRPAETIQAKVLGKKLGLPKKIVNKVLYDLLKSNQVVKQGETPPLWRLCEESRESIREKDQTQSSKDLEKEPGQSPYINQKVGGDFTTTSTP-----SPSKIPIDADSDTSDESEDSEGDDSCEKLLADQDKKTLSPTVQSVTLSTMADSKDSKEKILQYLYEAGTGNALVIAKNLGLRSAKQVNPTLYALEKQGDVNRNTEVNPPTWELSAHRQEKMDRQRKAAATANQDVNSAATLSLEDDEIANVALVNFEPMEGGGKPLVEMLDNDNVFGNTEIDIPGLEPVSKASDLSSSTHRNFQPNQFPYYQETPSNG---GEQSQWASDDIPEFLNTIR---SEVAVSLAAPPPPTQSME-SNRLQKLKEARSKNPVSGLMEFAQHLGYTCEFLLLEQSGPSHDPRFRMQVMLDGRRFPAAEGSNKKVAKKDAAAITLKILWKELDGGGGEEEEEPNIEGAGSTTDMADDMGGTDTPPQALSRSLPGGKNPVSVLMEHSQRSGHPIQFIKTGQEGPSHDPRFMFRVKVGERLFQEASAPSKKAARQLAAEEAVKELMGDGLLHLNKPPSSFCPMGDSESQPMFPACPSLPPLTAAELQAAHEAGVGDLINHLNNNAVSGLLEYARARGFAAEIRLVGQSGPSHEPKFTYQAKLGGRWFPAVCASNKKQGKQEAADAALRVLIGEAEKAARTG--ELMP----------------------ELPVSGSTIHDQIAMLSHQRFNALTARIQHSLLGRKILATIVMRNGTDSLGKVVSLGTGNRCVKGEELSLRGDTVNDCHAEIISRRGFIRFLYSELMKHWESPGDETIFELAGDG-KLKIKSDITFHLYISTAPCGDGALFDKSCS-EAAELNGSGHMPLFENIKQGKLRTKVENGEGTIPVESSDIVPTWDGIQHGERLRTMSCSDKILRWNVLGLQGALLTHFIHPIYLHSITLGYLYSHGHLTRAVCCRLSRDGDTFKSSLPANFTLNHPEVGRVSVYDSTRHTSKTKESSVNWSQPDQYSVEVLDGTKGKLDSPKMEVSRVSKSNLFRLFHALCQRAGRADLLALQSYAHAKMAATSFQEAKRLFFLALSQHGYGAWIGKPLEEKSFEGEAKSFEPMGGSGDVQASGCVVDPNSFLSSENNNFLSAAQGF", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :. * * . . * . . *. ** :*::**:*: .:** : * .. . * . :. : : . * . *.*. * *: *. :* .: *.* : :**: : : *:: * .* .:: * *. :* **: :*::**.* :..:: : .**** : :: : . . : : * :* .. * . **: * *** :**::.. ..** :***:** .*:::...* :*:**** * ..** * *: :::*::: :*.: : . .: : : . : . ... ...: . .:: * **. * .. .: : . ::: .. * *:. **:****: **:*: .*. . : *. : : .. :**.*.: ***:***:*:**. . **:* ::*****.*:***::**:::**.**.**...*****:*** :: ** .* .. .. : *: : . : : . .* . : *: .**.**:.*:* :: *:. :* .:***:*:*:* : * ** : * .******.*:*:*****:* * :. ::.*. ** .: . : :*:*:.:**.*.*.*******::*****::*:.****.*****.****:********** .******:************ *** : * *: * **::***:*********: **:** :* *********:*:*:...:.:* *************:.***:*:*************************: ...::*** * .* **:**. ::************** ****** .* * . * * *:*** ******************************: *****************************::*:**:*:*****:*:******:***::***.:*:..* * :***:*****:***.*::.****:****. .* *.:*:****:*.:*.* *:*****.*:* *: **. * *** *. *..** ** .:: **. * .* : *** **.** *** * :*.. ", "identical_positions": 499, "similar_positions": 328, "identity": "35.17%" }, { "cls_id": "homologset.agr.MGI:1889576", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A1B0GWU0-1", "uniprot_id": "A0A1B0GWU0_RAT", "id": "A0A1B0GWU0-1", "name": "Centriolin", "aln": "MKKGSE-RKLSKAKMPVSSHFPGPSSLRSSMRSRSLSPLIGSETPPFHPGGQCPAQAELTDENTMPLESQQHKGADPYVGVRYITEALIKKLTKQDNLALVKSLNLSLSKDGGKKFRYIENLEKCVKLEVLNLSYNLIAKIEKVDKLLRLRELNLSYNKISKIEGLENMCNLQKLNLAGNEIEHIPGWFSKKLKSLRVLNLKGNKISSLQDVSKLKPLQDLTSLTLIDNPVVALPHYLQFIIFHLRSLESLEGQPVTTQDRQEAFERFSLEEIERLEKDLEKKTVETEELKNKQTKFLEEIKHQDKLNKSLKEEAMLQKQSCEELESDLNTKKEL-------------LKQKTVELTRACQKQYELEQELAFYKIDAKFEPLNYYPSEYAEMDKSPDESPYIGKSRYKRNMFATETYIVSDAQAVQVRKMVPDGGQLRHEHAP-RAQAPPDVQLEDTGKQIVAAQTRLSELHHEIEAAEQKVLRATQEFKQLEEAIRQKKISEAEKDLLLKQLSGRLRHLNKLRQEALDLEAQLEKQRKEIAEKHEEINSAQLATDLLDSKDPKQSHMKAQKRGKEQQLDIMNKQYTQLESRLDEILCRIATETEEIKDLEQQLTDGQIAANEALKKDLEGVISGLQEYLGTIKGQAAQAQNECRKLQDEKETLLQRLTEVKQEKDELEIVAMDAENMRKELAELENALQEQHEVNASLQQAQGDLSAYETELETQLKLKDAETSQLKQELENLVRRTQLEQSVLQTELEKERQSLRDALGKAQSSEEKQQENSELRAQLKQLQDDNSLLKKQLKDFQSHLNHVVDGLIHPEEVAARVDELRKRLKLGAGEMRIHSPSDVLGKSLADLQKQFSEILARSQWEKEEAQVRERKLHEEMALQQEKLANGQEEFK-QACERALEARIKFDKRQHNARIQQLENEIHYLQENLKSMEKIQGLTDLQLQEADEEKERILAQLQELEKKKRREDARSQEQFLGLDTELKSLKKAVAASDKLAAAELTIAKEQLKSLHGTVMRINQERAEELQEAERSSREAMQAAKDLSRAEAEIELLQHLLREREGQFRDEMENAHVGSKGANLQLLEIEALKEAMAKQRAEITRLRDVLNLTGTGKKGGIENVVEEIAELRHAVSAQNEYISSMADPVQRQGCWYFMPPPPSSKVSSHSSQATKDSGLGLKCTASTPLRSQQAGQQEEKGSSGPLPASGYWVYSPIRSTPHKSFSKREDADNGGDSQEESGLDDQEDPPFVPPPGYIMYTVLPDGSPVPQGVALYAPSPPLPHSSHPLTPGTVVYGPPPAGAPIIYGPPPANFAVPLISMGVQHCNIPEHRDLENEVSRLEDITHHLKSKHQEERWLKTSRQHPEKEVEELHRNIDDLVQEKKELELEVEELHRTVERHQQRRDFIDGNVENLMTELEIEKSLKHHEDIVDEIECLEKTLLKRRSELREADRLLAEAESELACTKEKTKSAVEKFTDAKRNLLQTESDAEALEKRAQETALNLVKAEQQLRLLQADAEDLEQHKIKQEEILKEINKVVAAKDADFQCLNEKKEKLTEELQSLQRDIKAAEVNEDHHLQVLKESESLLQAKRAELETLKSQVTSQQQELAVLDSQLGHRREELLLLQDSLTQAKADLQEALTLGETEVAEKCSHIREVKSLLEELSFQKGELNVHISERRTQLTLIKQEIEKEEENLEVVLQQLSKHKTELKNVADILQLETNELQSLKLQHDQKVVELEKTQVDLLEGKLELESLQQTAQQQRRELERQRQLLERDRRETERVRAETQALQSCIECLNKEKEHLQEQCESWEKKSSHAKRVLAATEESNNTEQSKLGQLEVSVRKLQQELELLSQDKLALHSDSAQEQQQLQDKREALNSLQKELENTQDHLNLAKQDLMHTTKCQSALLSEQAQLQKDVSQWTARLESCQKETETKEQQLQELQDEIRESKLQLDQQEMVFQKLQKERESEEQKLVASIVSLEQQQGQLERELMDQKSKLEWLLTDVSAAEGRLRTLQKEERCTESLEKMLSQAKQQLSEREQQLMEKSGDLLALQKEADGMRADFSLLRNQFLTERKKAEKQVAGLKEALKIQRSQLEKNLLEQKQENSCMQKEMATIELVAQDNHERARRLMKELRQMQQEYLELKKQVANQKDFERRQMEVSNAMRTLKSEVKDEIRTSLRNLNQFLPDLPADLTAILERDDNLR-ELESVKENFPFTTNERIFEEKSNFPQVHIMDEHRRGEALRERLRHREDHLKAQLRDSMSKQAEVLIKGKRQTEGTLHSLRRQVDALGELVTSTSVDSAPSPSLSHLESSLVEDSQHGHSQSSFQVLQVPSE-PNIYRH", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A2AL36-1", "uniprot_id": "CNTRL_MOUSE", "id": "A2AL36-1", "name": "Centriolin", "aln": "MKKGSE-RRLSKAKMPLSSHFPGPSSLRSSMRSRSLSPLIGSETQPLHPGGQWPAQAELTDESTVPLEPQQRKGAESYVGVRYITEALIKKLTKQDNLALVKSLNLSLSKDGGKKFRYIENLEKCVKLEVLNLSYNLIVKIEKVDKLLRLRELNLSYNKISKIEGLENMCNLQKLNLAGNEIEHIPVWFAKKLKSLRVLNLKGNKISSLQDVSKLKPLQDLTSLVLIDNPVVALPHYLQFIIFHLRSLESLEGQPVTTQDRQEAFERFSLEEIERLEKDLEKKTVETEELKNKQTKFLEEIKNQDKLNKSLKEEAMLQKQSCEELESDLSTKKEL-------------LKQKTVELTRACQKQYELEQELAFYKIDAKFEPLNYYPSEYAEIDKYPDESPYIGKSRYKRNMFATETYIVSDAQAVQIRKMVPEGGQLRHEHTPPRVQAPPDLQLEDTEKKISAAQTRLSELHHEIETAEQKVLRATQEFKQLEEAIQQKKISEAEKDLLLKQLSGRLQHLNRLRQEALDLEIQMEKQRKEIAEKHEEINTVQLATDSLDPKDPKHSHMKAQKRGKEQQLDIMNRQYTQLESRLDEILCRIAKETEEIKDLEQQLTDGQIAANEALKKDLEGVISGLQEYLGTIKGQATQAQNECRKLQDEKETLLQRLTEVQQEKEELELIAMDAENMRKELAELESALQEQHEVNASLQQAQGDLSAYETELETQLKLKDAETSQLKQELEKLLRRTQLEQSVLQTELEKERESLRDALGKAQSSEEKQQENNELRTQLKQLQDDNSLLKKQLKEFQNHLNHVVDGLIHPEEVAARVDELRKRLKLGAGEMRIHSPSDVLGKSLADLQKQFSEILARSQWEKEEAQVRERKLHEEMALQQEKLANGQEEFR-QACERALEARIKFDKRQHNARIQQLENEIHYLQENLKSMEKIQGLTDLQLQEADEEKERILAQLQELEKKKKREDARSQEQFLGLDEELKSLKKAVAASDKLAAAELTIAKDQLKSLHGTVVRINQERAEELQEAERFSREAMQAAKDLSRAEAEIELLQHLLREREGQFRDEMENADLGAKGANSQLLEIEALNEAMAKQRAEITRLRDVLNLTGAGTKGGIENVLEEIAELRHAVSAQNEYISSMADPFRRQGWWYFMPPAPSSKVSSHSSQATKDSGLGLKYTASTPLRKPQPGQQEEKDSSGPLPASGYWVYSPIRSTLHKSFSKREDADSGGDSQEESGLDDQEEPPFVPPPGYIMYTVLPDGSPVPQGVALYAPSPPLPNSSHPLTPGTVVYGPPPAGAPIIYGPPPANFAVPLVPAGVQHCNIPEHHNLENEVSRLEDIMQHLKSKQREERRQKASTQHSEEEVDGLHRDIDDLLQEKKELELEVEELHRTIERHQQRKDFIDGHVENLMTELEIEKSLKHHEDIVDEIECLEKTLLKRRSELREADRLLAEAENELACTKEKTKSAVEKFTDAKRNLLQTESDAEALEKRAQETALNLVKAEQQLRLLQADAEDLEQHKIKQEEILKEINKVVAAKDADFQCLNEKKEKLTEELQSLQRDIKAAQHSEDHHLQVLRESETLLQAKRAELETLKSQVTSQQQELAVLDSELGHRREELLLLQDSLAQAKADLQEALTLGETEVAEKCSHIREVKSLLEELSFQKGELNVHISEKKTQLALIQQEMEKEEKNLQVVLQQLSRHKTELKNVADILQLETSELQGLKLQHDQKVVELEKAQVDVLEEKLELENLQQATQQQRRELERQRQLLERDRRETERVRAESQALQSCVECLSKEKEDLQGQCESWEKKSSHAQRVLAATEESNKMEQSNLGKLELSVRKLRQELEQLSQDKLALHSEVAEVQQQLQGKQEAINSLQEELDSTQDHLDLAKQDLIHTTKCQNELLNEQTQLQEDISKWMARLESCQKETETKEQQVQQLQDEIRESKLRLDQQEMMFQKLQKEREREEQKFEAGKVTLEQQQRQLEKELTDQKSRLKQLLTDVSAAEGRLGTLQEEERRIEGLERMLSQAKQQLSEREQQLMAKSGELLALQKEADDMRADFSLLRNQFLTERKKAEKQVAGLKEALKIQRSQLEKNLLEQKQENSCMQKEMATIELVAQDNHERARRLMKELSQMQQEYLELKKQVANQKDLERRQMEVSDAMRTLKSEVKDEIRTSLRNLNQFLPELPADLASILERNENLR-ELESLKENFPFTTKERIFEEKSNFPQVHIMDEHWRGEALRQRLRRHEDQLKAQLRHCMSKQAEVLIKGKQQTEGTLHSLRRQVDALGELVTSTSTDSASSPSLP----SLVEDSQHGHSQSSFQVLQVPLEEPNSYRH", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q7Z7A1-1", "uniprot_id": "CNTRL_HUMAN", "id": "Q7Z7A1-1", "name": "Centriolin", "aln": "MKKGSQQKIFSKAKIPSSSHSPIPSSMSN-MRSRSLSPLIGSETLPFHSGGQWCEQVEIADENNMLLDYQDHKGADSHAGVRYITEALIKKLTKQDNLALIKSLNLSLSKDGGKKFKYIENLEKCVKLEVLNLSYNLIGKIEKLDKLLKLRELNLSYNKISKIEGIENMCNLQKLNLAGNEIEHIPVWLGKKLKSLRVLNLKGNKISSLQDISKLKPLQDLISLILVENPVVTLPHYLQFTIFHLRSLESLEGQPVTTQDRQEAFERFSLEEVERLERDLEKKMIETEELKSKQTRFLEEIKNQDKLNKSLKEEAMLQKQSCEELKSDLNTKNEL-------------LKQKTIELTRACQKQYELEQELAFYKIDAKFEPLNYYPSEYAEIDKAPDESPYIGKSRYKRNMFATESYIIDSAQAVQIKKMEPDE-QLRNDHMNLRGHTPLDTQLEDKEKKISAAQTRLSELHDEIEKAEQQILRATEEFKQLEEAIQLKKISEAGKDLLYKQLSGRLQLVNKLRQEALDLELQMEKQKQEIAGKQKEIKDLQIAIDSLDSKDPKHSHMKAQKSGKEQQLDIMNKQYQQLESRLDEILSRIAKETEEIKDLEEQLTEGQIAANEALKKDLEGVISGLQEYLGTIKGQATQAQNECRKLRDEKETLLQRLTEVEQERDQLEIVAMDAENMRKELAELESALQEQHEVNASLQQTQGDLSAYEAELEARLNLRDAEANQLKEELEKVTRLTQLEQSALQAELEKERQALKNALGKAQFSEEKEQENSELHAKLKHLQDDNNLLKQQLKDFQNHLNHVVDGLVRPEEVAARVDELRRKLKLGTGEMNIHSPSDVLGKSLADLQKQFSEILARSKWERDEAQVRERKLQEEMALQQEKLATGQEEFR-QACERALEARMNFDKRQHEARIQQMENEIHYLQENLKSMEEIQGLTDLQLQEADEEKERILAQLRELEKKKKLEDAKSQEQVFGLDKELKKLKKAVATSDKLATAELTIAKDQLKSLHGTVMKINQERAEELQEAERFSRKAAQAARDLTRAEAEIELLQNLLRQKGEQFRLEMEKTGVG-TGANSQVLEIEKLNETMERQRTEIARLQNVLDLTGSDNKGGFENVLEEIAELRREVSYQNDYISSMADPFKRRGYWYFMPPPPSSKVSSHSSQATKDSGVGLKYSASTPVRKPRPGQQDGKEGSQPPPASGYWVYSPIRSGLHKLFPSR-DADSGGDSQEESELDDQEEPPFVPPPGYMMYTVLPDGSPVPQGMALYAPPPPLPNNSRPLTPGTVVYGPPPAGAPMVYGPPPPNFSIPFIPMGVLHCNVPEHHNLENEVSRLEDIMQHLKSKKREERWMRASKRQSEKEMEELHHNIDDLLQEKKSLECEVEELHRTVQKRQQQKDFIDGNVESLMTELEIEKSLKHHEDIVDEIECIEKTLLKRRSELREADRLLAEAESELSCTKEKTKNAVEKFTDAKRSLLQTESDAEELERRAQETAVNLVKADQQLRSLQADAKDLEQHKIKQEEILKEINKIVAAKDSDFQCLSKKKEKLTEELQKLQKDIEMAERNEDHHLQVLKESEVLLQAKRAELEKLKSQVTSQQQEMAVLDRQLGHKKEELHLLQGSMVQAKADLQEALRLGETEVTEKCNHIREVKSLLEELSFQKGELNVQISERKTQLTLIKQEIEKEEENLQVVLRQMSKHKTELKNILDMLQLENHELQGLKLQHDQRVSELEKTQVAVLEEKLELENLQQISQQQKGEIEWQKQLLERDKREIERMTAESRALQSCVECLSKEKEDLQEKCDIWEKKLAQTKRVLAAAEENSKMEQSNLEKLELNVRKLQQELDQLNRDKLSLHNDISAMQQQLQEKREAVNSLQEELANVQDHLNLAKQDLLHTTKHQDVLLSEQTRLQKDISEWANRFEDCQKEEETKQQQLQVLQNEIEENKLKLVQQEMMFQRLQKERESEESKLETSKVTLKEQQHQLEKELTDQKSKLDQVLSKVLAAEERVRTLQEEERWCESLEKTLSQTKRQLSEREQQLVEKSGELLALQKEADSMRADFSLLRNQFLTERKKAEKQVASLKEALKIQRSQLEKNLLEQKQENSCIQKEMATIELVAQDNHERARRLMKELNQMQYEYTELKKQMANQKDLERRQMEISDAMRTLKSEVKDEIRTSLKNLNQFLPELPADLEAILERNENLEGELESLKENLPFTMNEGPFEEKLNFSQVHIMDEHWRGEALREKLRHREDRLKAQLRHCMSKQAEVLIKGKRQTEGTLHSLRRQVDALGELVTSTSADSASSPSLSQLESSLTEDSQLGQNQEKNASAR-----------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M3ASW8-1", "uniprot_id": "A0A8M3ASW8_DANRE", "id": "A0A8M3ASW8-1", "name": "", "aln": "MKRGFQMRKQSPILGTKISKSP---------QSKPVTPNTTSLPEAEDGG----PREEPSDED-----------KRQYKGTRYITEDLIRRVTKCENVVLVRTLDLSMAMGSNHQFRYIENLDKCDRLQVLNLSNNRIERIEKLEKLCQLRELHLSRNRIHKIEGLEHMTKLQVLNLAFNNIEDLPVWFGKKLRSLQTVNLQSNNISSLHELAKLKPLNNLTCLTLAGNPVSSLAHYHLFLIFKLRSLEILDGQQISPQEREQAHQRFHMEEVERLEQELELRAEEIDRLQRERTIALEQLEQQETVNQNLRQQNQDQQHSHEELKRELDTKSELPPHHTPLLDSLCQLKQKTVELTQACQKHYELEQELAFHKIDVKFEPLPFYPDPEVEVDNLISESPYIGKSRQKRNIKFPS---ETENTGTQGQQKHPPASDLTETDSPGDYMS---------RHAQLAAEMKLQQLHKEIEAREQQILTASEELRQLEDAVSQRRISEAEKEQLRQELQRRIQNLGELRGEMEAVEKQLDRLNAERNQAQDEMEQLQNLLHSLDPSDPKHTHVKAQLSRKSQLLAIMSRKHQELERRLDDMITRIHKETEEIKDLEQQLTDGQIAANEALKRDLEGIISGLQEYLRGVKDQARRAQSDCRRLQREKDTLQHLLDMKEQEFTQLENKALSAEITQKELELQKQEFDNLMKENEELKRARGQVSEYEAELESQLQQRDTEATQLKEELDRLRRLTQMEHSALQAELQKERQAKENALAQVRMAADKELENTQLLQQINALQEERDCLKEEVEAFQDDLNSVREQLLCPESVARHLGELRRGITTGQKELSFEDLGEPVNKKFMELQQEVHRVVSAAQRDRDEAQRCQDRLTGEMSSLRERLRKYQERHQTQTTERRGE-----------------EAELHRLREELEEAREQHYLMAQRLEETEIDRDRILGELEEQDKQMNAEKTQTQEQLESLNLEMQALRRSFSSADRQAAQQLITAKDKLHSLHSTVEKINLERAANAEELQSTRIQAAQAIQDLTNAEAEIQVLQKLLSDR----VQETDGNLHGLQNSQIQQEELDRLNQALKRQQAQTKRLRDQLAQAKGANNINLDELLEEIGALKETLLQQNNFLSSLGDPSPNTGYWYYVPS--NQHAPSLGSQGTQDSGLGSVHPHS-PERNRRSGNRACRE-RRPPANGGYWVYSPNPYSHGK-----RDAQVSRDSGRESDMEGTRFTPLSAPAGFTLH----DSTAFPPGSFIYSHSVPG----LPIGASTVLYGPPPDPARLVYGPPPANLTVPLVPSGTLHCNVPGHQDLE----------RDLKKAERRLREECADRAHSEQEQHTLQDKTAELQQEIKHLRRTVRTLQRHTSG-----------LESTLSHAEEEQ------CVLGEVECLEKTLLKRRAELREADRRLLEADAQLKNTQTKTEENIHHYNEAKKRMEETERELAEIEKRAQDSGKLLVQSKQQLRSLQEEVMTLQKRKEDKERSLHDAEEVLTCHDSKFQDVSRKLERANDRLEIAEKELRETQSMEVKLLQSCREMENSLAQRKTKLDEVNTQVMLQQKELSLLDRKLEQWKREEEVLRVSVEQHRQALLDVLRQGEEDAKLLQQRVQELRVDVHSLAVQKGELDSQLSERKTRLAQLKKDQQQEEETLQSLRSVIKKHKAELARMLEMIQLETGELEDVKLQCNQKLEQLEKSQETLLQVRVELQCVQQELQEQREEAERQ---MEKDRVELHSLQQKSLHLQQQTEAAVQERSSLQEQCRNLEARRTHAQRCLEAAETRTSEAETELLRVQAELNKLQQELKQTQDLHLEISRDNVAVQK---RHEEELSKLKKQLVDSQTLVDEVREEGKSARKQWEELVKKQKELKAELKEREEKIRRRQQKMERMEEQLQELKAEISVKQTQLEDHEKLMRVQQQQSTDLEQQLRLK----EQKLQAVERALVLKLERMEQLTVADLDLQG-------EYKHCTALQQQVDQLEQELCERDARLQQAFKDTHRLQETLLSEKTNHSHTN------------------------RSNLQR----VEKDRVRLQSDLLTIEKSAQENHQQARTLQKQLGTISQELLSLKDTVQT---LQKQEEESSSAFWEIN-----------------------RSTAELETPSSASSDTDSLKENRPAVTLS------MGNPAYNTEDEQWRGEALRERLRQQEDHLKVQLRRRMFSQQEALSQRRLQTEGSIQGLRRRVDKLDQLLGSSSKDCSYLSDQE-----LLPKHTNGRDRKKWSADPFELK-------", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "**:* : : * . *: * :*:.::* * . . . * : * :**. : *.***** **:::** :*:.*:::*:**:: ...::*:*****:** :*:***** * * :***::** :****:** *:* ****:*:* :** **** *:**.:* *:.***:**:.:**:.*:****::::*****::* .* * *** :*.** * **:***** *:** ::.*:*::*.:** :**:****::** : * :.*: ::* **::::*:.:*:.*::: *::* ***: :*.**.** *****:***:****:*********:***.***** :**. .*:*: .********* ***: .. . ..* :: * :* . . : : **: :*.:**.*** **::* *::*::***:*: ::**** *: * ::*. *:: :..** * :* *::: . * :.*:: * . **..***::*:*** *.* * **.::: :** ***::: ** .*********:***:**********:****:******** :*.** :**.:**:*: **:** : * :** :** *:.** :*** :. ::: : * .*::::*::* **:***::*: :*:*:.***:**:.: * **:*:*.**:**:***:: .:**.:.: : :*: **.:* ::: **::.. **:::: **..** * : *: **.** ::.***: :. * *: :.. .: :.*.: :**::. .::: :: :::*** : :* **: :*:* . **..: *: ** * * *:* *:*:*:. .: : * :*:*:: :::***.:*.* :*: . *.:::***. .*: *:: *:::.:::*: *: :* **::*:***.** :** *** : :* : :* ** :**:.*****::**:** :: * : * .:: * *:: *:::: :*::: **:: * : .: .:::::***. *:. : **:::**:.** . * **::*. ..:..* .**.*:***:* . * * *. :.*:: : * . .******* * **: . ** .** ::. . .*: .*.*: :: *.:..* * :*: . * *: ..**:***** * ::*****.*:::*::. *. ***:* *::** :.**. .:. * :. :.*:* . *: . :* ** * *. *. *:* . :*. ::. * *: ::.*:**:********:******* * **: :* *: **:. :.::.:**: : :** : :*:***::. **::.**** ** :. *:::* .:*. *:: :::::.:*:.** :..* *: .:.*: ::::. :: * : ** :* * * ::::*: :::** **:*:::** :* : :.* :*: *: * : * :.* ** :. .:::*:: :..*:.*****: ::**::*:*: :::: ::**:.*: : :.:**:** .: :::***. **:.:*** :*:: :***:* :*: ::**: :** *:*: * * * :*:*: * . : :: **. *. :*:. ** :* * : ::::* * *:* .. :::* ::: .:.**:***. . :* : : *: :.* :..*:::* . * :: .::: : * . *:.:* .*: ::.: ::. *:: * ::*:* *: ** .: :* ::* ::: *:: *.:: ::: :*: * : .::. : : * : .*:: :.* :::*.**: :* : **: . :::.* . **:*:: :::. :*.:: *** **:**::** * *:* :. * .**. : . ::::: * *.*: :: : ** .. : :*:*** * . . . . : **: ******::**::**:**.*** * .* *.* : : ****:::.***:** *.:*: *:* *.: .. * . *:.:.. ", "identical_positions": 759, "similar_positions": 803, "identity": "32.24%" }, { "cls_id": "homologset.agr.MGI:1889583", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q925Q9-1", "uniprot_id": "SH3K1_RAT", "id": "Q925Q9-1", "name": "SH3 domain-containing kinase-binding protein 1", "aln": "---MVEAIVEFDYQAQHDDELTISVGEVITNIRKEDGGWWEGQINGR--RGLFPDNFVREIKKDVKKDLLSNKAPEKPMHDVSSGNSLLSSETILRTNKRGERRRRRCQVAFSYLPQNDDELELKVGDIIEVVGEVEEGWWEGVLNGKTGMFPSNFIKELSGESDELGISQDEQLSKSRPEGFLPASLLPFPAHGAKGKTTFEGTILYRAAPGKTEGHRRYYSLRETTGSESDGGDSSSTKSEGANGTVATAAIQPKKVKGVGFGDIFKDKPIKLRPRSIEVENDFLPVEKTIGKKLPPATSTPDPSKTEMDSRTKTKDYCKVIFPYEAQNDDELTIKEGDIVTLINKDCIDVGWWEGELNGRRGVFPDNFVKLLPSDFDKEGN-----RPKKPP-------------------------------------------------PPSAPVIKQG--------------------------------------AGTTERKHEIKKIPPERPETLPNRTEEKERPEREP--------------------------------KLDLQKP--------------------------------------SVPAIPPKKPRPPKTNSLNRPGVLPPRRPERPVGPLTHTRGDSSKIDLAGSTLSGILDKDLSD--------------------------RSNDIDLEGFDS-VISSTEKLSHPTTSRPKATGRRPPSQSLTSSSLSSPD-----------------------------------------IFDSPSPEED------------------KEEHISLAHRGIDVSKKTSRTVTISQVSD-NKASLPPKPGTMAAASSGPASLSSVASSPMSSSLGTAG----------------------QRASSPSLFSAEGKAKTESAVSSQAAIEELKMQVRELRTIIETMKDQQKREIKQLLSELDEEKKIRLRLQMEVNDIKKALQSK---------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8R550-1", "uniprot_id": "SH3K1_MOUSE", "id": "Q8R550-1", "name": "SH3 domain-containing kinase-binding protein 1", "aln": "---MVEAIVEFDYQAQHDDELTISVGEVITNIRKEDGGWWEGQINGR--RGLFPDNFVREIKKDMKKDLLSNKAPEKPMHDVSSGNALLSSETILRTNKRGERRRRRCQVAFSYLPQNDDELELKVGDIIEVVGEVEEGWWEGVLNGKTGMFPSNFIKELSGESDELGISQDEQLSKSRPEGFLPASLLPFPAHGAKGKTTFEGTILYRAAPGKTEGHRRYYSLRETTGSESDGGDSSSTKSEGANGTMATAAIQPKKVKGVGFGDIFKDKPIKLRPRSIEVENDFLPVEKTIGKKLPPATSTPDPSKTEMDSRTKTKDYCKVIFPYEAQNDDELTIKEGDIVTLINKDCIDVGWWEGELNGRRGVFPDNFVKLLPSDFDKEGN-----RPKKPP-------------------------------------------------PPSAPVVKQG--------------------------------------AGTTERKHEIKKIPPERPETLPNRTEEKERPEREP--------------------------------KLDLQKP--------------------------------------SVPAIPPKKPRPPKTNSLNRPGALPPRRPERPVGPLTHTRGDSPKIDLAGSALSGILDKDLSD--------------------------RSNDIDLEGFDS-VISSTEKLSHPTTSRPKATGRRPPSQSLTSSSLSSPD-----------------------------------------IFDSPSPEED------------------KEEHISLAHRGIDVSKKTSKTVTISQVSD-NKTSLPPKPGTMAAASSGPASLSSVASSPMSSSLGTAG----------------------QRASSPSLFSTEGKPKMEPAVSSQAAIEELKMQVRELRTIIETMKDQQKREIKQLLSELDEEKKIRLRLQMEVNDIKKALQSK---------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q96B97-1", "uniprot_id": "SH3K1_HUMAN", "id": "Q96B97-1", "name": "SH3 domain-containing kinase-binding protein 1", "aln": "---MVEAIVEFDYQAQHDDELTISVGEIITNIRKEDGGWWEGQINGR--RGLFPDNFVREIKKEMKKDPLTNKAPEKPLHEVPSGNSLLSSETILRTNKRGERRRRRCQVAFSYLPQNDDELELKVGDIIEVVGEVEEGWWEGVLNGKTGMFPSNFIKELSGESDELGISQDEQLSKS--------------------------------------------SLRETTGSESDGGDSSSTKSEGANGTVATAAIQPKKVKGVGFGDIFKDKPIKLRPRSIEVENDFLPVEKTIGKKLPATTATPDSSKTEMDSRTKSKDYCKVIFPYEAQNDDELTIKEGDIVTLINKDCIDVGWWEGELNGRRGVFPDNFVKLLPPDFEKEGN-----RPKKPP-------------------------------------------------PPSAPVIKQG--------------------------------------AGTTERKHEIKKIPPERPEMLPNRTEEKERPEREP--------------------------------KLDLQKP--------------------------------------SVPAIPPKKPRPPKTNSLSRPGALPPRRPERPVGPLTHTRGDSPKIDLAGSSLSGILDKDLSD--------------------------RSNDIDLEGFDS-VVSSTEKLSHPTTSRPKATGRRPPSQSLTSSSLSSPD-----------------------------------------IFDSPSPEED------------------KEEHISLAHRGVDASKKTSKTVTISQVSD-NKASLPPKPGTMAAGGGGPAPLSSAAPSPLSSSLGTAG----------------------HRANSPSLFGTEGKPKMEPAASSQAAVEELRTQVRELRSIIETMKDQQKREIKQLLSELDEEKKIRLRLQMEVNDIKKALQSK---------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A0B4KI34-1", "uniprot_id": "A0A0B4KI34_DROME", "id": "A0A0B4KI34-1", "name": "", "aln": "MENNICAIVEYEYAAKEPDELDLQKGAIIHRIKQMPGGWWQGTLKASGVTGMFPDNFVRVLESGVSSN----------GNGTTGSGDHIEVGTAVQLRDKSATSNRRCKVIYSYTQVNDDELTLAVGDVIEFLGEVEEGWWRGRLRSKVGVFPSNFVQHIE-PSPVLASKRPP-------------------------------------------------TIGATVTTSALTSKAANVANVAATATVPTGGAVPP--ASTSISTSTTKQATKSRATAAAAASAPAEPAAIVSGSGAAAGGGAAAAVPMLPPKPQ-REFCRVEFPYAPQNDDELELKVDDIIAVISTELPDKGWWKGEIRGKVGVFPDNFVKMLAPSEATAAPPLPRPRPRTRPGMGGTGAGSGSGIIDGVRTPRRTQRGGSFEFLGARMASFITTIFAPINEPPSATQITQNQRKVSNTASTTSHMTTTNSSNSSTTSVTTQQQKEQIGGSSSTTSKVYIKKTGSSSNSTTSSTTTASSSAGRKESFGSRDSLNDILSETGLPTGNVAAQRKSLENKNLDLTKPPGVGASVSIGQQRSSTSSATTSSATTVATGLTSSSVSKSMENMLDEKVKSPPPPVLSKKPSVPLKKTPTGGVPMTGNLLGGKKKNTEG-KLTTAVSHDLADGLAASKMLSGANQLPESGAAGNVVIRRAATIAVEDTDFDRVERASILTDMRQGRVKAPKRRPPSAAINVLGESNNNSVYVNGSGMSGSGGAGSASELSEDGGAGGKTSDDNSTGEEPQLAKPKPREWEKKKAPWMEELKASQVTRKKTSPSVEPRGASVAERTSKLFAAEQAVSSNSSSITTKVQSSAVTSSMFVENSTTSSSVITSSSHTTTNDAIMSRSLSAAKVQTASSDEETRATRPNSLAIRNQRSVSPLVKSSNASSSQ-SQEEKPTSQLNNHQDASSSRVAQLEQRVDKLEGLVLNQQRTIEELVNALKSEAERVKILRSELDKYAQCVTQV", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : ****::* *:. *** :. * :* .*:: ****:* ::. *:******* ::. :..: : ..... :. * :: ..:. .***:* :** ***** * ***:**.:********.* *..*.*:*****::.:. * *. .: :: *. :.: ..::.. . .*..*:.*.. * ...:. ..:. * *. : . . :. . ..: . . .: . : .:.: :::*:* *** .****** :* .**:::*..: * ***:**:.*: *********:*... . . **:. * ****. :.*. :.:* * *** .. . .. * .. . *: :*** ** *: : :* :.* . *.: :* ::. *:* . .. * : * *: :.:**:* *: * :*. * :. :. *:. .* **. ***** ::. . *. : : .*.*.* *: *: ** ..:::**: .: .*. . *.:*:..* : *. .. . *:.:.* ::** *: **. *. :. ..: . .. ..*. * .. * .: : ::. :* .. .: ** ..:*: : : *. * :::: :**:*: ", "identical_positions": 182, "similar_positions": 260, "identity": "18.09%" }, { "cls_id": "homologset.agr.MGI:1889585", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZIF4-1", "uniprot_id": "D3ZIF4_RAT", "id": "D3ZIF4-1", "name": "Sal-like protein 1", "aln": "----MSRRKQAKPQHFQSDPEVASLPRRDGDTEKGQPSRPTKSKDAHVCGRCCAEFFELSDLLLHKKSCTKNQLVLIVNESP--ASPPKTFPPGPPSLNNPDEQMKFVASKADQEDCGDLS-EHKGLDREESMETEVPVATSSSSSNGG-------TLSSVTNIATPSCHSGSSTGTSAITTSLPQLGDLTTLGNFSVINSNVIIENLQSTKVAVAQFSQEA-----RCGGASGGKLLISALMEQLLALQQQQIHQLQLIEQIRHQILLLAS-QNADLSAS-SVPSQGTLRTSANPLTTLSSHLSQQLAVAAGLAQSLASQSANISGVKQLP-PVQLPQSSSGT-IIPPSSGPSPNVSMVTATVPTPSSEKVASNAGASH--VSPPAVSASSSPA-AFAISSLLSPASNPLLPQPTPANAVFPTPLPNIATTAEDLNALSALAQQRKSKPPNVTAFEAKSTSDEAFFKHKCRFCAKVFGSDSALQIHLRSHTGERPFKCNICGNRFSTKGNLKVHFQRHKEKYPHIQMNPYPVPEHLDN----------------VPTSTGIPYGMSIPPEKPVTSWLD---TKPVLPTLTTSVGLPLPPTLPSLTPFIKT---------------------------------EEPAPIPISHSAASPQGSVKSDSGAPDLATRNPSGVPEEAEGSAVPPFGGKGEDSSVVS-SIPTAGSSALNSPVADGG-----------------------------------------------------------------AGG---TTFTNPLLPLMSEQFKAKFPFGGLLDSAQASETSKLQQLVENIDKKATDPNECVICHRVLSCQSALKMHYRTHTGERPFKCKICGRAFTTKGNLKTHYSVHRAMPPLRVQHSCPICQKKFTNAVVLQQHIRMHMGGQIPNTPVPDNYPESMESDTGSFDEKNFDDLDNFSDENME---ECPEGSIPDTPKSADASQDSLSSSPLPLEMSSIAALENQMKMINAGLAEQLQAS-LKSVENGSVEGDVLTNDSSSVGGDVESQSSGSPAISESTSSMQALSPSNSTQEFHKSPNVEEKPQRVGPGEFANG--LSPTPVNGGALDLTSSHAEKIIKEDSLGILFPFRDRGKF----KNTACDICGKTFACQSALDIHYRSHTKERPFI-------CTVCSRGFSTKGNLKQHMLT------------HQMRDLPSQLFEP----SSNLGPNQNSAMIPASSLSSLIKTEVN---------GFVHVSPQDSKDAPTSHVPSGPLSSSATSPVLLPALPRRTP------------KQHYCNTCGKTFSSSSALQIHERTHTGEKPFACTICGRAFTTKGNLKVHMGTHMWNSTPARRGRRLSVDGPM-----------------TFLGGNP---VKFPEMFQKDLAARSGSGDPSSFWNQYTAALSNGLAMKANEISVIQNGGIPP-IPGSLGNGSSSPISGLTGNVEKLGNSEPSAPLAGLEKMASSENGTNFRFTRFVEDSKEIVTS----------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9ER74-1", "uniprot_id": "SALL1_MOUSE", "id": "Q9ER74-1", "name": "Sal-like protein 1", "aln": "----MSRRKQAKPQHFQSDPEVASLPRRDGDTEKGQPSRPTKSKDAHVCGRCCAEFFELSDLLLHKKSCTKNQLVLIVNESP--ASPAKTFPPGP-SLNDPDDQMKDAANKADQEDCSDLS-EPKGLDREESMEVEVPVATTTTTTTGGSGGSGGSTLSGVTNITTPSCHSGCSSGTSAITTSLPQLGDLTTLGNFSVINSNVIIENLQSTKVAVAQFSQEA-----RCGGASGGKLLISTLMEQLLALQQQQIHQLQLIEQIRHQILLLAS-QSADLPAAPSIPSQGTLRTSANPLTTLSSHLSQQLAVAAGLAQSLASQSANISGVKQLP-HVQLPQSSSGTSIVPPSGGTSPNMSIVTAAVPTPSSEKVASNAGASH--VSSPAVSASSSP--AFAISSLLSPESNPLLPQPTPANAVFPTPLPNIATTAEDLNSLSALAQQRKSKPPNVTAFEAKSTSDEAFFKHKCRFCAKVFGSDSALQIHLRSHTGERPFKCNICGNRFSTKGNLKVHFQRHKEKYPHIQMNPYPVPEHLDN----------------VPTSTGIPYGMSIPSEKPVTSWLD---TKPVLPTLTTSVGLPLPPTLPSLTPFIKT---------------------------------EEPAPIPISHSAASPQGSVKSDSGAPDLATRNPSGVPEEVEGSAVPPFGGKGEESNMASSAVPTAGNSTLNSPVADGG-----------------------------------------------------------------PGG---TTFTNPLLPLMSEQFKAKFPFGGLLDSAQASETSKLQQLVENIDKKATDPNECIICHRVLSCQSALKMHYRTHTGERPFKCKICGRAFTTKGNLKTHYSVHRAMPPLRVQHSCPICQKKFTNAVVLQQHIRMHMGGQIPNTPVPDNYPESMESDTGSFDEKNFDDLDNFSDENME---ECPEGSIPDTPKSADASQDSLSSSPLPLEMSSIAALENQMKMINAGLAEQLQAS-LKSVENGSMEGDVLTNDSSSVGGDMESQSAGSPAISESTSSMQALSPSNSTQEFHKSPGMEEKPQRVGPGEFANG--LSPTPVNGGALDLTSSHAEKIIKEDSLGILFPFRDRGKF----KNTACDICGKTFACQSALDIHYRSHTKERPFI-------CTVCNRGFSTKGNLKQHMLT------------HQMRDLPSQLFEP----SSNLGPNQNSAVIPANSLSSLIKTEVN---------GFVHVSPQDSKDAPTSHVPQGPLSSSATSPVLLPALPRRTP------------KQHYCNTCGKTFSSSSALQIHERTHTGEKPFACTICGRAFTTKGNLKVHMGTHMWNSTPARRGRRLSVDGPM-----------------TFLGGNP---VKFPEMFQKDLAARSGSGDPSSFWNQYTAALSNGLAMKANEISVIQNGGIPP-IPGSLGSGSS-PISGLTGNVEKLGNSEPSAPLAGLEKMASSENGTNFRFTRFVEDSKEIVTS----------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9NSC2-1", "uniprot_id": "SALL1_HUMAN", "id": "Q9NSC2-1", "name": "Sal-like protein 1", "aln": "----MSRRKQAKPQHFQSDPEVASLPRRDGDTEKGQPSRPTKSKDAHVCGRCCAEFFELSDLLLHKKNCTKNQLVLIVNENP--ASPPETFSPSP-PPDNPDEQMNDTVNKTDQVDCSDLS-EHNGLDREESMEVEAPVANKSGSGTSSGSHSSTAPSSSSSSSSSSGGGGSSSTGTSAITTSLPQLGDLTTLGNFSVINSNVIIENLQSTKVAVAQFSQEA-----RCGGASGGKLAVPALMEQLLALQQQQIHQLQLIEQIRHQILLLAS-QNADLPTS-SSPSQGTLRTSANPLSTLSSHLSQQLAAAAGLAQSLASQSASISGVKQLP-PIQLPQSSSGNTIIPSNSGSSPNMNILAAAVTTPSSEKVASSAGASH--VSNPAVSSSSSP--AFAISSLLSPASNPLLPQQASANSVFPSPLPNIGTTAEDLNSLSALAQQRKSKPPNVTAFEAKSTSDEAFFKHKCRFCAKVFGSDSALQIHLRSHTGERPFKCNICGNRFSTKGNLKVHFQRHKEKYPHIQMNPYPVPEHLDN----------------IPTSTGIPYGMSIPPEKPVTSWLD---TKPVLPTLTTSVGLPLPPTLPSLIPFIKT---------------------------------EEPAPIPISHSATSPPGSVKSDSGGPESATRNLGGLPEEAEGSTLPPSGGKSEESGMVTNSVPTASSSVLSSPAADCG-----------------------------------------------------------------PAGSA-TTFTNPLLPLMSEQFKAKFPFGGLLDSAQASETSKLQQLVENIDKKATDPNECIICHRVLSCQSALKMHYRTHTGERPFKCKICGRAFTTKGNLKTHYSVHRAMPPLRVQHSCPICQKKFTNAVVLQQHIRMHMGGQIPNTPVPDSYSESMESDTGSFDEKNFDDLDNFSDENME---DCPEGSIPDTPKSADASQDSLSSSPLPLEMSSIAALENQMKMINAGLAEQLQAS-LKSVENGSIEGDVLTNDSSSVGGDMESQSAGSPAISESTSSMQALSPSNSTQEFHKSPSIEEKPQRAVPSEFANG--LSPTPVNGGALDLTSSHAEKIIKEDSLGILFPFRDRGKF----KNTACDICGKTFACQSALDIHYRSHTKERPFI-------CTVCNRGFSTKGNLKQHMLT------------HQMRDLPSQLFEP----SSNLGPNQNSAVIPANSLSSLIKTEVN---------GFVHVSPQDSKDTPTSHVPSGPLSSSATSPVLLPALPRRTP------------KQHYCNTCGKTFSSSSALQIHERTHTGEKPFACTICGRAFTTKGNLKVHMGTHMWNSTPARRGRRLSVDGPM-----------------TFLGGNP---VKFPEMFQKDLAARSGSGDPSSFWNQYAAALSNGLAMKANEISVIQNGGIPP-IPGSLGSGNSSPVSGLTGNLERLQNSEPNAPLAGLEKMASSENGTNFRFTRFVEDSKEIVTS----------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F1QI36-1", "uniprot_id": "F1QI36_DANRE", "id": "F1QI36-1", "name": "Sal-like protein 1", "aln": "----MSRRKQAKPQHFQSDSQLV-LAEHNGDTETNPDDSPCKDSGAHVCSRCCAEFFELSDLEQHQKNCTKNQLVLIVNENP--VSPSGTFSPGS-SPHNPDEQMNDTTNNTDQAELTDLL-EQNILDKEEAMDTEMSGVSAPHN-DGNGRMAGSSPLSGVGTGHGTLGSTGSNLGSSVISASLPQLGNLTELGNFSMINSNVIIENLQSTKVAVAQFSQET-----RATGGQ--RVAVPALMEQLLALQQQQIHQLQLIEQIRHQILLLAS-QSPELQAP-PSSSPVTLGSGTSPLTTLSSHLSQQLAAAAGLAQSIASQSASISSLKQMANVAQLPQSNSSVGESSQSLAAPG-----PAPVNAQPLEKRPGNAGSLHPPLGNPSLAKSSTP--AFAMGNLLNPVANTLLPQPPPGNPIFSSALPSVGSTVEDLNSLAALAQQRKGKPPNVSSFEPKSSSEDTFFKHKCRFCGKVFGSDSALQIHLRSHTGERPYKCNICGNRFSTRGNLKVHFQRHKEKYPHIQMNPYPVPEHLDN----------------IPTSTGIPYGMSMPPEKPVTSWLD---SKPVLSTLTSSVGMLLPPTIPSLPPFIKK---------------------------------EENNSLAIS----SPSHSAKSDSGPADTPMKNTDSVLEEGESTTLPTSNGKAEENNQSSNLLSNMSSAVEGTIEYTTS-----------------------------------------------------------------NSP---PMATNPLMPLMSEQFKAKFPFGGLLDPLQGSETSKLQQLVENIDRKVADPNECVICHRILSCQSALKMHYRTHTGERPFKCKVCGRAFTTKGNLKTHYSVHRAMPPLRVQHSCPICQKKFTNAVVLQQHIRMHMGGQIPNTPLPDNYPESMGSDAGSFDERNIDDLDNFSDDNMEGIEDGPDSSIPDTPKSVDASQDSLCSSPT-LHESFGMDERIQEKSANHGAGEEVQYDQGKSVENGLVEGDRFTNDSSSLGGDIESQSAGSPAVSESTSSMQAPSPSNGIFQQQKSPSMEDRQQRALSLEHISASLMHSNSASPGALDLTSVNSSK----DPISMLFPFRERGTL----KNTACDICGKTFACQSALDIHYRSHTKERPFI-------CTVCNRGFSTKGNLKQHMLT------------HQMRDLPSQLFEPNTSLASSLASSPTPSLLSVGPLSSMMKTEVN---------GFLHGLQPEVKDLPPALVT----SSASTSPVLSAAPPRRTP------------KQHFCTTCGKTFSSSSALQIHERTHTGEKPFACTICGRAFTTKGNLKVHMGTHMWNSAPARRGRRLSVDGPM-----------------AFLGTNP---VKFPELFQKDLSSRAGNGDPTSFWNQYAAAFSNGLAMKTNEISVIQNGGLPPPLSGSVGNGGSSPIGGLTGSMEKLHNSEPNPALAGLEKMANTENGTHFRFTRFMED-KEIVTN----------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0ACD6B6U0-1", "uniprot_id": "A0ACD6B6U0_DANRE", "id": "A0ACD6B6U0-1", "name": "Sal-like protein 1", "aln": "----MSRRKQAKPQYVLLD--------HTMEIE------PSPTCDVHICEQCCAEFSSITELYQHQKDCSKDQLVLIVSENESLDSPPSALTVNS-PFFNTEEHSDGVTNNDSTEDLGDSSNEGTLLEVEEPLDVLEIHG-----------------------IDKKSHECSNDGLSSAYSASLPQDIALLELCKLSAFNSNVFIENLENTKVAVAQFSQETPLK-TSCINASNAKKVDLGLIEQLLALQQQQMQQLKLIEEIRAQIMLLAT-QNSKTPLT----TNSNGLSQSRSLIKLSSELSEQLTAAAGLAENLAAN------AKQSTHVVPQNQDGLRGEKEDSKVTSKIRDNTFPMKLDIDQSGNQSLHDSKVSNKVDGGANLKTPSP--SPASDGIVN---KLELPHKPNSFNISANSLPSIGAIVEDLNALTALAQHRKAKPVNVSLCEHKRPSEDCIFKHKCRFCAKVFGSDSALQIHLRSHTGERPYKCNICGNRFSTRGNLKVHFQRHKEKYPNVLMNPYPVPEHLDN----------------VLTSTGIPYGMSVPQEKPPLSWLD---SKPLVG---NSIGFMLSSSLPGLPVIIKK---------------------------------EEEG-----------VSITKPHSPVVSELTKRINGHQEEFVCSPPIISNEKFQEVNQRLSVSTLLRSSREGSREDIAV-----------------------------------------------------------------NTS----VNTGLITKLKSEQLEAKFLLGSLPNPLGASETSKLEQLVENIDKKYTDPNECGICHRVLSCQSALKMHFRTHTGERPFKCRVCGRAFTTKGNLKTHYSIHRSMPPLRIQNSCPICQEKFTNAMVLQQHIHMHMGGHIPNVPMHDSSEELMDQDL-------VESMDTFPNEDTD------TMQGASDLKNPDSLTESECSSPA---SSVFARSESQIKVAN---VEKLENTSKLVIQDGSVEGDCLTQGLASQN--IEHESLRRRIPSESTASWSPSSPKGYTTIDPKSAESN-----------------NSNLTVSRLLDGASGEVQK----DTLTMVFPYINQGSL----KSNVCDICNKMFACQSALDIHYRSHTKERPFI-------CTACNRGFSTKGNLKQHMLT------------HQMRELPSQLFEP---ANKILVLPPNHLLPSVETNIPPKRIEHN---------GFIKK---DLKDSPSCIFS----SSASTMPVLPTPTLRRTA------------KQHFCQTCGKTFSSSSALQIHERTHTGEKPFACNICGRAFTTKGNLKVHMGTHMWSSSPARRGRKLSVDG-------------------PYITSNS---ERFQDGHPKDVVAKVRNGDSVGLWSQH----HNGSGLRTNEIPVIQNGAIPH-------------LSISAGHLENLEKLQLNRALPWLERLS--ENGAAFHFRQLVEDHKTTLMD----------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VKH3-1", "uniprot_id": "Q9VKH3_DROME", "id": "Q9VKH3-1", "name": "", "aln": "---------------------------------------------------MCSIFRNRINYRGTGGTRSGSGERERDRDRD-------------------RDRDRDRERDRDTLLAKELDADSNNNGTEPQMEAEAVPESDTER----------------ETAEERGEEQEPENSNEALDLSLISSGGRESLP----GSGHVSLEALQHTKVAVAQFAATA-------MAGNHQSADLAMVQSTIFNVQRQHLMQLQLIQHLQSQLKRAEA-AALGRHSH-SDEEEEEPEPEPEPKKQPTNGLKEELELEQGPESEQDQE---------------------------------------SRREENSKTDKRGTEDRKAEPEGYQSMMCDISSS----LASSIITNHDPPPAPNEPNCLEMLQR------RTEEVLDSASQSLHAAQMQEEYSEYASKEAQSRGEIFKHRCKYCGKIFGSYSALQIHLRSHTGERPFVCNVCGSKFTTKGNLKVHYQRHTQIFPPMLLPPGVAPNVGHSG---------------QGQVQGEQYPIRLPFAPPVAPVGQEQHQNQVEEPEEIRQEIPVPQAEDLSKPMVKE---------------------------------KEKSHSPVER--VKTPKEVKTDAALPSSEKPEKEISKPVVTSSRRNGSVRKRQTSAVSPPQEDRERDLVEHLHIAKLV-----------------------------------------------------------------RRSSASRESQPAEYSLAQMERIIDKSWEDLIEIDKTSETSKLQQLVDNIENKLTDPNQCIFCQKVMSCRSSLQMHIRTHTGERPFRCKICGRAFATKGNLKAHMSIHKIKPPMRSQFKCPVCHQKFSNGIILQQHIRIHT--------MDDGSGGQGAPAANPGEAERLGIEDQNSNKSLG-----TSDTLDFSTTISDHSGQRSESSQGGDFDEFMTMDSTDDSRDNSSAATATPHPLERERDREKERERRIPNDCSDERSHSNPDLTGGRSESGEMPAMDLSSPSSNSGR-IFATGLANGAAGGGSGNGGLPMLGMPMPPNLLLMAAAREEMHALGHAHAKFPLLPFGPLGFMGLHPPPNVCNLCFKMLPSLAALESHLQSEHAKEPATGHAQRPQCSDAGSPYGAKLTLNPNLFAKKPPSSSSSSSGEKLPESSNPPFPAENPPATPIKEDPDQEQLMVEEGASAGEGSGT---------GATSNYPQEAGDAEQSLMKMQLHAHRFPASPLDFQQALMSAGPPTSSLDPPVNNKHFCHVCRRNFSSSSALQIHMRTHTGDKPFQCNVCQKAFTTKGNLKVHMGTHMWTNPTSRRGRRMSLELPMRPGPNSGQGHPGSSAEQEFMQRRPELFFPYLPPFFNGLPPKPGELSPGAFPNIPPPPFANGGKYPYPPGLLGFPGFLAQHPYILERRSSSKSPTPEPAQSPALREEEGSGNIWHPLSRIKVENNQNESMGGFNEQEDHAETDATGGDNDESESRDAEK", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P39770-1", "uniprot_id": "SALM_DROME", "id": "P39770-1", "name": "Homeotic protein spalt-major", "aln": "MKNHLSNVLCAMRSDFKDNHQETINKMIQFGTVKYGIVKQLKDRARSADKDIGSDQEENGGCSPLTTATTTASPSRSPEPEEEQPEEQSTSEQSIPEQSTPDHQLENDIKSEAKSEIEPVE-DNNNRVAMTKPSSEEREPNASGSMPSSPVAEASAEEAATERTPEKEKEKDVEVDVEKPDEAPSSAVPSTEVTLPGGAGAPVTLEAIQNMQMAIAQFAAKTIANGSNGADNEAAMKQLAFLQQTLFNLQQQQLFQIQLIQQLQSQLALNQAKQEEDTEEDADQEQDQEQETDTYEEEERIADMELRQKAEARMAEAKARQHLINAGVPLRE----------SSGSPAESLKRRREHDHESQPNRRPSLDNTHKADTAQDALAKLKEMENTPLPFGSDLASSIITNHDDLPEP---NSLDLLQKR----AQEVLDSASQGILANSMADDFAFGEKSGEGKGRNEPFFKHRCRYCGKVFGSDSALQIHIRSHTGERPFKCNVCGSRFTTKGNLKVHFQRHAQKFPHVPMNATPIPEHMDKFHPPLLDQMSPTDSSPNHSPAPPPLGSAPASFPPAFPGLQNLYRPPMEILKSLGAAAPHQYFPQELPTDLRKPSPQLDEDEPQVKNEPVEEKDQREEHEQEMAECSEPEPEPLPLEVRIKEERVEEQEQVKQEDHRIEPRRTPSPSSEHRSPHHHRHSHMGYPPVVQPIQPAALMHPQSSPGSQSHLDHLPTPGQLPPREDFFAERFPLNFTTAKMLSPEHHSPVRSPAGGALPPGVPPPPHHHPHHMARSPFFNPIKHEMAALLPRPHSNDNSWENFIEVSNTCETMKLKELMK--NKKISDPNQCVVCDRVLSCKSALQMHYRTHTGERPFKCRICGRAFTTKGNLKTHMAVHKIRPPMRNFHQCPVCHKKYSNALVLQQHIRLHTGEPTDLTPEQIQAAEIRDPPPSMMPGHFMNPFAAAAFHFGALP-GGPGGPPGPNHGAHNGALGSESSQGDMDDNMDCGEDYDDDVSSEHLSNSNLEQEGDRSRSGDDFKSLLFEQKLRIDATGVVNTNPVRPRSSASSHGHSVGSTSAPTSPSVHASSQVIKRSSSPARSEASQG-ALDLTPRAAPTSSSSSRSPLPKEKPVSPPSLPRSPSGSS-----HASANILTSPLPPTVGIDCLPPGLQHHLQQQHQHLMQQQAAVAAAAAAQHHHHQQMAALHQHQEQLRREAAEAQQKAAAAAAAAAAAAAAQRQTPPQARDQRQEGGPGAGPPPNPLMGARPPFGMFPNLPLFPPATTQNMCNAMNQIAQSVMPAAPFNPLALSG----------VRGSTTCGICYKTFPCHSALEIHYRSHTKERPFKCSICDRGFTTKGNLKQHMLTHKIRDMEQETFRNRAVKYMS-----------------EWNEDRE--------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . : .: . : . . . . : . : .. * :* :: ::*:***: : . : . :: :*:*:: *::**:.:: *: : . . :. . . : . : . . ..::. * : : : . :***:*::*.*:*** ******:********: **:**.:*:*:******:*** : :* : : . *: .. . * . : : :: .* .: . . : . * . .: : .** **::*:. :.* :***:* .*.:::**:*:*:** *********:*::*****:******:* ::*: **:* .**:*::*::*.::*****::* . . . : *. : : . . : : * . . . *.. :. : . :* * .:: . :. .:: . . : .:: : :: : : : . . . . * . : . * * :.*.. ***:** *:** ::** *.:* :.******** ** ** . . *. ::. : . ", "identical_positions": 144, "similar_positions": 206, "identity": "9.27%" }, { "cls_id": "homologset.agr.MGI:1889595", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9ERT9-1", "uniprot_id": "PPR1A_MOUSE", "id": "Q9ERT9-1", "name": "Protein phosphatase 1 regulatory subunit 1A", "aln": "MEPDNSPRKIQFTVPLLEPHLDPEAAEQIRRRRPTPATLVLTSDQSSPEIDEDRIPNSLLKSTLSMSPRQRKKMTRTTPTMKELQTMVEHHLGQQKQGEEPEGATESTGNQESCPPGIPDTGSASRPDTPGTAQKSAESNPKTQEQCGVEPRTEDSSAHMLPLDSQGASLV", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P19103-1", "uniprot_id": "PPR1A_RAT", "id": "P19103-1", "name": "Protein phosphatase 1 regulatory subunit 1A", "aln": "MEPDNSPRKIQFTVPLLEPHLDPEAAEQIRRRRPTPATLVLTSDQSSPEVDEDRIPNPLLKSTLSMSPRQRKKMTRTTPTMKELQTMVEHHLGQQKQGEEPEGATESTGNQESCPPGIPDTGSASRPDTSGTAQKPAESKPKTQEQRGVEPSTEDLSAHMLPLDSQGASLV", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q13522-1", "uniprot_id": "PPR1A_HUMAN", "id": "Q13522-1", "name": "Protein phosphatase 1 regulatory subunit 1A", "aln": "MEQDNSPRKIQFTVPLLEPHLDPEAAEQIRRRRPTPATLVLTSDQSSPEIDEDRIPNPHLKSTLAMSPRQRKKMTRITPTMKELQMMVEHHLGQQQQGEEPEGAAESTGTQESRPPGIPDTEVESRLGTSGTAKKTAECIPKTHERGSKEPSTKEPSTHIPPLDSKGANSV", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "** **********************************************:*******. *****:*********** ******** *********:********:****.*** ******* ** .*.***:*.**. ***:*: . ** *:: *:*: ****:**. *", "identical_positions": 135, "similar_positions": 20, "identity": "78.95%" }, { "cls_id": "homologset.agr.MGI:1889615", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0ABK0LVF4-1", "uniprot_id": "A0ABK0LVF4_RAT", "id": "A0ABK0LVF4-1", "name": "", "aln": "MKFNAAHYLLPLLPALVLSTRQDYEELEKQLKEVFKERSTVLRQLTKTSRELDGIKVNLQSLKNDEQSSKTDVQKLLELGQKQREEMKSLQEALQNQLKETSEKAEKHQATINFLKTEVERKSKMIRDLQNENKSLKNKLLSGSKLCGIHAEESKKIQAQLKELRYGKKDLLFKAQQLTELEQKLAVAKNELEKAALDRESQMKAMKETVQLCLSSVFRDQPPP-LSLFPSNPTQMLHPPRTIA-SRIPETRTKSKPQQSSPGHHDSSQVQAT----KEESRRTTVCGTQDEGSSCLAKHEEGPKSNNTAESELTTQKLQMPLCSECEEKKVPEKTSASFDGTPAREEKLL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8BGY3-1", "uniprot_id": "LUZP2_MOUSE", "id": "Q8BGY3-1", "name": "Leucine zipper protein 2", "aln": "MKFNAAHYLLPLLPALVLSTRQDYEELEKQLKEVFKERSTVLRQLTKTSRELDGIKVNLQSLKNDEQSSKTDVQKLLELGQRQREEMKSLQEALQNQLKETSEKAEKHQATINFLKTEVERKSKMIRDLQNENKSLKNKLLSGSKLCGIHAEESKKIQAQLKELRYGKKDLLFKAQQLTELEQKLAVAKNELEKAALDRESQMKAMKETVQLCLSSVFRDQPPP-LSLMPSNPTQMLHPPRTVA-SRIPEARTKSKPQPSSPGHHDSSQVQAT----KEESRRPSVCGPQDEGSSCLVKHEEGPQSNSTAESELTTQKLQMPICSECEEKKGPENPSASFDGTPAREEKLL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q86TE4-1", "uniprot_id": "LUZP2_HUMAN", "id": "Q86TE4-1", "name": "Leucine zipper protein 2", "aln": "MKFSPAHYLLPLLPALVLSTRQDYEELEKQLKEVFKERSTILRQLTKTSRELDGIKVNLQSLKNDEQSAKTDVQKLLELGQKQREEMKSLQEALQNQLKETSEKAEKHQATINFLKTEVERKSKMIRDLQNENKSLKNKLLSGNKLCGIHAEESKKIQAQLKELRYGKKDLLFKAQQLTDLEQKLAVAKNELEKAALDRESQMKAMKETVQLCLTSVFRDQPPPPLSLITSNPTRMLLPPRNIA-SKLPDAAAKSKPQQSASGNNESSQVEST----KEGNPSTTACDSQDEGRPCSMKHKESPPSNATAETEPIPQKLQMPPCSECEVKKAPEKPLTSFEGMAAREEKIL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A5D8S1-1", "uniprot_id": "LUZP2_DANRE", "id": "A5D8S1-1", "name": "Leucine zipper protein 2", "aln": "MKFIGAVYLLFLLPALSFNS--SYEGLEKKLKEVFTERTGILRHLSKTSKELDSIKGNLQSLKNEDAVPKKDVQRILELSHKQRDEMKSLQAALQKQLDDAAERAEKQQATIKFLKMEMEKKTKIIKDLQQENKSLKNKLLSGNKLCDIHAEESKKIQAQLKELRYGKKDLIFKGQQLMDLENKLKVAKDELEKAALDKESQLKALKDTVHICFSSVLHSQTAS-LHRFPATPTNLLRYSALVNNSRVTFQQPHMKDIPKVPRITTTSKLPVSSAVMRRESTGPKDCQMVKVGSDCSHNQTES--SSVMKKTFGHSQSKTPEQNGQGQARTAEESVKTDGELKKTQSDKHN", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*** * *** ***** :.: .** ***:*****.**: :**:*:***:***.** *******:: .*.***::***.::**:****** ***:**.:::*:***:****:*** *:*:*:*:*:***:************.***.***********************:**.*** :**:** ***:********:***:**:*:**::*::**::.*... * :.:.**.:* . : *::. .: * . . :*:: : :. . .. * . * * :: *. *. :: .*. .: : :. *. :. : ::.:* ", "identical_positions": 166, "similar_positions": 103, "identity": "47.29%" }, { "cls_id": "homologset.agr.MGI:1889623", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9ERP3-1", "uniprot_id": "TRI54_MOUSE", "id": "Q9ERP3-1", "name": "Tripartite motif-containing protein 54", "aln": "MNFTVGFKPLLGDAHNMDNLEKQLICPICLEMFSKPVVILPCQHNLCRKCANDVFQASNPLWQSRGSTTVSSGGRFRCPSCRHEVVLDRHGVYGLQRNLLVENIIDIYKQESSRPLHAKAEQH-LMCEEHEDEKINIYCLSCEVPTCSLCKVFGAHKDCEVAPLPTIYKRQKSELSDGIAMLVAGNDRVQAVITQMEEVCQTIEDNSRRQKQLLNQRFETLCAVLEERKGELLQALAREQEEKLQRVRGLIRQYGDHLEGSSKLVESAIQSMEEPQMALYLQQAKELINKVGAMSKVELAGRPEPGYESMEQFSVSVEHVAEMLRTIDFQPGAAGDEEDDDMALDGEEGNAGLEEERLDVPEGSGLH", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q5XIH6-1", "uniprot_id": "TRI54_RAT", "id": "Q5XIH6-1", "name": "Tripartite motif-containing protein 54", "aln": "MNFTVGFKPLLGDAHNMDNLEKQLICPICLEMFSKPVVILPCQHNLCRKCANDVFQASNPLWQSRGSTTVSSGGRFRCPSCRHEVVLDRHGVYGLQRNLLVENIIDIYKQESSRPLHSKAEQH-LMCEEHEDEKINIYCLSCEVPTCSLCKVFGAHKDCEVAPLPTIYKRQKSELSDGIAMLVAGNDRVQAVITQMEEVCQTIEDNSRRQKQLLNQKFETLCAVLEERKGELLQALARVQEEKLQRVRSLIRQYGDHLEASSKLVESAIQSMEEPQMALYLQQAKELINKVGAMSKVELAGRPEPGYESMEQFSVIVEHVAEMLRTIDFQPGASGDEEDDEVTLDGEEGNTGLEEERLDGPE--GLH", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9BYV2-1", "uniprot_id": "TRI54_HUMAN", "id": "Q9BYV2-1", "name": "Tripartite motif-containing protein 54", "aln": "MNFTVGFKPLLGDAHSMDNLEKQLICPICLEMFSKPVVILPCQHNLCRKCANDVFQASNPLWQSRGSTTVSSGGRFRCPSCRHEVVLDRHGVYGLQRNLLVENIIDIYKQESSRPLHSKAEQH-LMCEEHEEEKINIYCLSCEVPTCSLCKVFGAHKDCEVAPLPTIYKRQKSELSDGIAMLVAGNDRVQAVITQMEEVCQTIEDNSRRQKQLLNQRFESLCAVLEERKGELLQALAREQEEKLQRVRGLIRQYGDHLEASSKLVESAIQSMEEPQMALYLQQAKELINKVGAMSKVELAGRPEPGYESMEQFTVRVEHVAEMLRTIDFQPGASGEEE--EVAPDGEEGSAGPEEERPDGP------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q5RHH1-1", "uniprot_id": "Q5RHH1_DANRE", "id": "Q5RHH1-1", "name": "Tripartite motif-containing protein 54", "aln": "MNFTLGFKPSIGDSSSMENLERQLICPICLEIFSKPVVILPCQHNLCRKCANDVFQASNPLWQNRASTTVSTGGRFRCPSCRHEVVLDRHGVYGLQRNLLVENIIDIYKSESTRPLLPKTEQQQLMCDQHEEEKINIYCLTCETPTCSMCKVFGAHKDCDVAPLPVIYKKQKTELSDAIAILVAGNDSIQALISQMEDICRSIKDNGRRQIQHISDKFDELYAILEERKRELIETVGCEQDRKLGHVRSLIRRHGDHLEMSVKLVETAIQSMEEPQMAVFLQSTKDVFKKITDTAKASNIERTEVGYESMAHFIINTEDVANMLRHINFRTGKD-EEDSGDEAPEGLTTSTGQSGESGTR-------", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "****:**** :**: .*:***:*********:*******************************.*.*****:*************************************.**:*** .*:**: ***::**:********:**.****:**********:*****.***:**:****.**:****** :**:*:***::*::*:**.*** * :.::*: * *:***** **::::. *:.** :**.***::***** * ****:***********::**.:*::::*: :*.. *.* ***** :* : .*.**:*** *:*:.* :*: : : :* .:* . * ", "identical_positions": 235, "similar_positions": 83, "identity": "64.03%" }, { "cls_id": "homologset.agr.MGI:1889642", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q496Z0-1", "uniprot_id": "ELP2_RAT", "id": "Q496Z0-1", "name": "Elongator complex protein 2", "aln": "MVSSVLEVSYVFCCPNRARGALSWNSGPGGLLAFGTSCSVVLYDPQKK----VVITNLNGHTARVNCLHWIRTEDGSPSTELVSGASDNRVIHWELENNQVLKSVRLQGHEGPVYAVHGIYQSGPSDGEQHALIASAASDSTVRLWSK--KGSEVKCLQILKFGDGFVLTVCLSTLPDT-DAPVLACGDDGGRIHLFVQQDD----------WFQKMLSLCGHEDWIRGVEWATFGR--DLFLASCSQDCLIRIWRLYMKPTSL----------ETEDG-SIRLKENTFTIKDGGVSTTVAVILETVLAGHENWVNAIHWQPSFYKDGVLHQPVRLLSASMDKTMILWAPDEESGVWLEQVRVGEVG--------GNTLGFYGCQFGENGSMIIAHAFHGAMHLWKQSTVNPRQWAPEIVISGHFDGVQDLIWDPEGEFIITTSTDQTTRLFAPWKKKNQ----SQVTWHEIARPQIHGYNLKCLAMIDRFQFVSGADEKVLRVFSAPRNFVENFSVISRQSLS-HMLYDEDNDLPEGATVPALGLSNKAVFEGDMTY-LTSEEEELLS-PAFGYPQVIFQPAVLSEPPTEDHLLQNTLWPEVQKLYGHGYEIFCVTCNNSKTLLASACKAAQKEHAAIILWSTTSWKQVQ-SLAYHTLTVTQMAFSPDDKFLLAVSRDRTWSLWKRQDVTSAEFDPFFSLFAFTNKITSVHSRIIWSCDWS--PDSKYFFTGSRDKKVVVWGECNS---SYNPMEHPINPCSSILDVG-SCVTAVSVCPVLNP--AQRYIVAVGLESGKICIYSWSKTNQ--ETKDWTSCVETTPSQSHTLGIRRLCWKSCSG--------STEQSE-EGTEWLDFASCGEDHTVKIYRVNRCAL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q91WG4-1", "uniprot_id": "ELP2_MOUSE", "id": "Q91WG4-1", "name": "Elongator complex protein 2", "aln": "MVSSVLEVSHVFCCPNRVRGALSWNTGPGGLLAFGTSCSVVLYDPQKK----VVITNLNGHTARVNCLQWIRTEDGSPSNELVSGGSDNRVIHWELENNQVLKSVRLQGHEGPVCAVHAIYQSGPSEGEQHALIASAASDSTVRIWSK--KGSEVKYLQTLSFRDGFVLSVCLAILPGT-NVPVLACGDDDCRIHLYIQQDD----------QFQKALSLCGHEDWIRGVEWATFGR--DLFLASCSQDCLIRIWRLYMKPASF----------ETKDG-SLRLKENTFTIKDGGVRTTVAVTLETVLAGHENWVNAVHWQPSFYKDGVLQQPVRLLSASMDKTMILWAPDEESGVWLEQVRVGEVG--------GNTLGFYDCQFGENGTMIIAHAFHGALHLWKQSTVNPRQWAPEIVISGHFDGVQDLMWDPEGEFIITTSTDQTTRLFAPWKKKDQK-DRSQVTWHEIARPQIHGYNIKCLAMIDRFQFVSGADEKVLRVFSAPRNFVENFSVISRQSLS-HMLCD-DQDLPEGATVPALGLSNKALFQGDIAS-QPFEEDELIS-PAFGSPQVTFQPAVLNEPPTEDHLLQNTLWPEIQKLYGHGYEIVCVACNNSKTLLASACKASQKEHAAIILWSTASWKQVQ-SLAFHTLTVTQMTFSPDDKFLLAVSRDRTWSLWKRQDATSSEFDPFFSLFAFTNKITSVHSRIIWSCDWS--PDNKYFFTGSRDKKVVVWGECKS---SHNPMEHPIRPCSSILDVG-SSVTAVSVCPVLNP--AQRYIVAIGLESGKICIYSWNKTNQ--EINDWTSCVETNPSQSHSLGIRRLCWKSCSDDDDDDDDDDTEQSE-EGPEWLHFASCGEDHTVKIYRVNRRAL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6IA86-1", "uniprot_id": "ELP2_HUMAN", "id": "Q6IA86-1", "name": "Elongator complex protein 2", "aln": "MVAPVLETSHVFCCPNRVRGVLNWSSGPRGLLAFGTSCSVVLYDPLKR----VVVTNLNGHTARVNCIQWICKQDGSPSTELVSGGSDNQVIHWEIEDNQLLKAVHLQGHEGPVYAVHAVYQRRTSDPALCTLIVSAAADSAVRLWSK--KGPEVMCLQTLNFGNGFALALCLSFLPNT-DVPILACGNDDCRIHIFAQQND----------QFQKVLSLCGHEDWIRGVEWAAFGR--DLFLASCSQDCLIRIWKLYIKSTSL----------ETQDDDNIRLKENTFTIENESVKIAFAVTLETVLAGHENWVNAVHWQPVFYKDGVLQQPVRLLSASMDKTMILWAPDEESGVWLEQVRVGEVG--------GNTLGFYDCQFNEDGSMIIAHAFHGALHLWKQNTVNPREWTPEIVISGHFDGVQDLVWDPEGEFIITVGTDQTTRLFAPWKRKDQ----SQVTWHEIARPQIHGYDLKCLAMINRFQFVSGADEKVLRVFSAPRNFVENFCAITGQSLN-HVLCNQDSDLPEGATVPALGLSNKAVFQGDIAS-QPSDEEELLTSTGFEYQQVAFQPSILTEPPTEDHLLQNTLWPEVQKLYGHGYEIFCVTCNSSKTLLASACKAAKKEHAAIILWNTTSWKQVQ-NLVFHSLTVTQMAFSPNEKFLLAVSRDRTWSLWKKQDTISPEFEPVFSLFAFTNKITSVHSRIIWSCDWS--PDSKYFFTGSRDKKVVVWGECDS---TDDCIEHNIGPCSSVLDVG-GAVTAVSVCPVLHP--SQRYVVAVGLECGKICLYTWKKTDQVPEINDWTHCVETSQSQSHTLAIRKLCWKNCSG--------KTEQKEAEGAEWLHFASCGEDHTVKIHRVNKCAL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q05AM5-1", "uniprot_id": "ELP2_DANRE", "id": "Q05AM5-1", "name": "Elongator complex protein 2", "aln": "MAAPVMDTCHVSCCANRAPNVVSWGRG--GLIAFGTCNSVAIYNPEEI----RVVDLLNKHTGRVNAVQWVHEPDCSPENQLISGGSDNNVIVWEKLDGKFRACAVCSGHSGPVCAVDAVSLSSS-----HLLVASASSDSTVKLWTY--SSDAAECLQTVAFGSGFMMDVSLALLPGS-RVPVLACGGDDSRVHLYVQLSG----------QFQRVLTLTGHEDWVRGVEWANKDG--ELWLASCSQDCLIRVWRLFAKTAAEP---------DLQTDGIIKMKENIFQVSGE----EFAVTLETVLAGHENWVYGIHWQPPSVKGDSVEQSLKLLSASMDKTMILWGPEEDSGMWVEMVRVGEVG--------GNTLGFYGCQMSPDGSMILAHAFHGALHLWHHDSN--QEWRPSVVISGHFNAVQDMSWDPEGEFIITVGSDQTTRLFTPWTRKGS----SQITWHEISRPQIHGYDMQCLTMVGRFQFVSGADEKVLRVFKAPRNFVENFAHISGTSLEKLLGCNDIADLPEGASTPALGLSNKAVFQGDLASPSPQQDGGDFNSLSDQYKESYFQPLKLAEPPTEDDLLQNTLWPEVQKLYGHGFEMFCLASDCARTVVASACKASKAEHASILLWSTASWKQLQ-SLSCHSLTITQMAFSPNGQLLLAVSRDRTWSLWRR-GNPDLDTEAMFSLYANTSKDTSVHTRIIWSCDWS--ADNKYFVTSSRDKKVIIWGHAVSGVAVGEGEDARVTSCSSVLDVG-DSATAVSICPFLCS--DHSYLLAVGLENGQILLYKWKPLEDLSSESDWSRCKDTDACQGHTMVVKRLRWRPRLGRGG-----HGGQDSKEEQAWVQLASAGADHVVKIFDINLSAL", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q7K4B3-1", "uniprot_id": "ELP2_DROME", "id": "Q7K4B3-1", "name": "Elongator complex protein 2", "aln": "---MQVENLHTSVACNRCTECADWGPN--GWIAYGACNAIAIMDPKFQGNSAKVLFTLVEHTKRVNTVRWLD------CDKLLSGGDDAIAILWELDETGTTKSFTLKGHTSGVNTVDGIRQQDG-----SWLLATAAADTTIKLWTF--QDNNYVCFQTISLSDGFCFCLRLQLLPKS-NQVLLAFSGDDETVSLWSEQVETAGEGDSLGRQFQRKHKLTGHEDWVRGLDFVVDGE--DLLLASGSQDNFIRLWRIAPRSKEQMQENRVDLHQLSHNDDEIKVEEKILQLGKEA---WYAVSLESVLYGHEGWIYGVHWHKT------PDQELRLLSASIDKTVIIWAPTEEG-IWLEEVRVGEVG--------GNSVGFYGGKFSGDGHSIMAHSYQGGFHIWSQDPDRPQLWTPGVIVGGHYGEVRDLAWEHSGAYLMTASADQTTRLHAPWLQDGA-----NPTWHELARPQIHGYDMQALALLSRYKFASGAEEKIVRTFQAPANFIENFRHISGIEND-DAGDVLLDSLPKGASVPSLGLSNKAVYKVDSEVESTSKTS------KDEYPDNYFVPIALETPPQEETLMQNTLWPELQKLYGHGYEIFALAATADGSLLASTCKASNAEHAQIILWNPSNWKQIQ-KLSGHQLTVTQLSFSPDSRYLLSVSRDRRWCLYERQDSSVS-----YQLVASTDKSNGVHTRIIWSCDWS--HDGQFFVTSSRDGKVVVWKKEED----CKESSLNGWQANGVLELKNESITAVAFSNSYLSGTDDTYILALGTETGLIKIYQF-------VRGAWKLLSDLNKSQAHHLTVRRLQFRPGKQ--------------------LQLASCGEDHLVRIYDIKLT--", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P42935-1", "uniprot_id": "ELP2_YEAST", "id": "P42935-1", "name": "Elongator complex protein 2", "aln": "-MVECITPEAIFIGANKQTQVSDIHKVK-KIVAFGAGKTIALWDPIEP-NNKGVYATLKGHEAEVTCVRFVPD-----SDFMVSASEDHHVKIWKFTDYSHLQCIQTIQHYSKTIVALSAL---------PSLISVGCADGTISIWRQNIQNDEFGLAHEFTIKKGFFYPLCLSLSKVEEKKYLLAIGGTNVNVFIASFILSDSG-----IEKCRVVAELEGHEDWVKSLAFRHQETPGDYLLCSGSQDRYIRLWRIRINDLIDD---------SEEDSKKLTLLSNKQYKFQIDDELRVGINFEALIMGHDDWISSLQWHES---------RLQLLAATADTSLMVWEPDETSGIWVCSLRLGEMSSKGASTATGSSGGFWSCLWFTHERMDFFLTNGKTGSWRMWATKDNIICDQRLGISGATKDVTDIAWSPSGEYLLATSLDQTTRLFAPWIYDASGRKREIATWHEFSRPQIHGYDMICVETVTDTRFVSGGDEKILRSFDLPKGVAGMLQKFVGIQFE------EKSEMPDSATVPVLGLSNKAGEDDANEDDEEEEGG------NKETPDITDPLSLLECPPMEDQLQRHLLWPEVEKLYGHGFEITCLDISPDQKLIASACRSNNVQNAVIRIFSTENWLEIKPALPFHSLTITRLKFSKDGKFLLSVCRDRKWALWERNMEDNT--------FELRFKNEKPHTRIIWDADWAPLEFGNVFVTASRDKTVKVWRHQKE------------PADDYVLEASIKHTKAVTAISIHDSMIREKILISVGLENGEIYLYSY-------TLGKFELITQLNEDITPADKITRLRWSHLKR-----------------NGKLFLGVGSSDLSTRIYSLAYE--", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : *: . :*:*: ::.: :* * * * .*. :::: ::*...* . *: : . * . . .. . *: ..:* :: :* .. : . : .** : * :** .. . : : : * *****::.: : : *.* *** **:*:: . . . : : .: .: :*::: **:.*: .::*: ::**:*: *.::::* * * . :*: :*:**:. *.: **:. . : : . : :.* * *: *. .* ::::.. ******.:** . ****::*******:: .: : :*.**.:**::* *. * .. : : . . .:*..*:.* ******* . . : * ** *: * :: ****::******:*: .: .::**:*:: : ::* * ::.. .* ::: * * **:*:: ** : : **:*.*** *.*:.: * *:****..**: .: *.*.*** .* :* . . . :*: .**: . . ::::* * * * :* : : : : :* : : :. . * .:*. : ", "identical_positions": 158, "similar_positions": 225, "identity": "17.83%" }, { "cls_id": "homologset.agr.MGI:1889651", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9DCR4-1", "uniprot_id": "EID1_MOUSE", "id": "Q9DCR4-1", "name": "EP300-interacting inhibitor of differentiation 1", "aln": "MAEMAELCELYEESNELQMDVLPGEG---YMEVGRGAR----GPAP-------EEGPMEEEAGP--AAARAQRGLFP----------EAGADLE----GDEFDDWEDDYEFPEEERWSGAMHRVSAALEEANKVFLRTARAGDALDGGFQARCEKSPFDQLAFIEELFSLMVVNRLTEELGCDEIIDRELMLTREEETT", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "B1WC74-1", "uniprot_id": "B1WC74_RAT", "id": "B1WC74-1", "name": "", "aln": "MAEMAELCELYEESNELQMDVLPGEG---DMEVGRGAR----GPAP-------EEGPMEEEAGP--SAARAQRGLFP----------EAGADLE----GDEFDDWEDDYDFPEEERWSGAMHRVSAALEEANKVFLRTAQAGDALDGGFQARCEKSPFDQLAFIEELFSLMVVNRLTEELGCDEIIDRE----------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9Y6B2-1", "uniprot_id": "EID1_HUMAN", "id": "Q9Y6B2-1", "name": "EP300-interacting inhibitor of differentiation 1", "aln": "MSEMAELSELYEESSDLQMDVMPGEGDLPQMEVGSGSRELSLRPSRSGAQQLEEEGPMEEEEAQPMAAPEGKRSLANGPNAGEQPGQVAGADFESEDEGEEFDDWEDDYDYPEEEQLSGAGYRVSAALEEADKMFLRTREP--ALDGGFQMHYEKTPFDQLAFIEELFSLMVVNRLTEELGCDEIIDRE----------", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*:*****.******.:*****:**** **** *:* *: ******** . :*...:*.* ****:* *:*********::****: *** :*********:*:**** .. ******* : **:********************************* ", "identical_positions": 117, "similar_positions": 26, "identity": "58.79%" }, { "cls_id": "homologset.agr.MGI:1889679", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9W269-1", "uniprot_id": "Q9W269_DROME", "id": "Q9W269-1", "name": "Solute carrier organic anion transporter family member", "aln": "------------------------------------------------MVQSENPSSLGAELQDLEHGRRESRDESDVESRLLNNGKSYDKEKEAGNQDGEETTPKTGKSKKKKQKSEQDRLMTA---------------EINKLLAESPLEKNVTCGFWIFKGTFYQRFANQTAYVLLYGIVGCIFSMTYAYFNGTITTIEKRFKIPSKNTGIISVGNDISQTLVSAVLAYYAGKGHRPRWIGFGLLTIVFFCILTTAPHFLYGPGEDALALTSEFGG-----MPDENATMEAIEEQRSKTLCRL-------------NGGGAECEVGEGNFAPQLLLFVAQFISGIGGSLYYTLGVSYMDDNTKKSKTPALLSLSYFLRMLGPAIGYALASFCLRLYIAP----QMHPVINNKDPRWLGAWWLGWLVMGGLLSFSGVFLSMFPKELPRAVARRK-VEENRRREKERLSVKSTEKERLTAELDQKTTAEAK----------ASFQDMLKTFRRLITNKTYMCNTLSSIFYLVGYTPYWIFTPKYIEVQYRQSAATSSMVTGTVALAFSAVGVLLSGFIISRYKPRARYMAAWNVIVGFLTVAGILAYAFIGCPGNESS------VIVNIHDSSLAGNTTTCNSACSCDYVRYSPVCGE-NNMTYISACHAGCKKL-LVNSEGKKIFYDCSCIPSDDAGNSTSQFKR---------------------LTSFDLSNDEVSQNTSVHSQLEALANGQAMPGACPVN--CWTQFVAFLAVMCCLKFVGASGRASNFLVSVRCVPEKDKTAAMGFGMTLCSMLAFIPSPIFFGWVFDRVCLVWG-KTCTNKGNCWLYDPLSMRYTLN------FTAAVFIAIGAIFDLGVWYYAKDLKIFDEDVKEVEMKIVQHEEEANNEKNTEI----------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9W271-1", "uniprot_id": "Q9W271_DROME", "id": "Q9W271-1", "name": "Solute carrier organic anion transporter family member", "aln": "------------------------------------------------MTEERGK-------VDLEK----SETLPFIEKPFAIS----DKERESAPEN--ETEGEDG-------------------------------------------GKDTYCGFWIFKGPSMQRFATEHMYVILYGLAGCVMTMTFAYFNGTITTLEKRYKIPTKVSGIISVGNDISTMLTAAILGYYAGHRHRPRWMGIGLLTIVAFCLLTSSLHFLYGAGEDALQLTREFG--------QVNETLTNQE--RDKKLCQP-------------TAGGCVQEE-VGLWVPQVFLFAAQLISGVGQALFYTLGIAYMDDNTSKAKTPAMLSMSTFLRMLGPAIGYSLAAVCLRLYIEP----TLEPLIGQEDPRWLGAWWLGWLVLAAITLVSAILLFMFPKQLPSARKR-------------RLQLKQDER-KQSLPLNER-----------------SLADMMKTVKKLSKNKVYVYNTMASILYFFGYMVYWIFTPKYIETQYRQSAAMATMATGTVALGFSAAGILISGYVISKYKPSARAMAAWNAIVDFVTVAGILCYVAIGCEGSDR---------LNTLTTLSAGN--SCSASCHCDYVHYAPVCSA-DNITFISACHAGCSER-TKDALGRTIYTGCECLGSS------------------------------------SLNSEPESQ--------------FAVDGTCPVD--CFNEFLIFLGVMCFLKLVGASSKSTNLLLALRCMPPDEKTFALGLGSMAASLLGFIPSPIFFGWLIDNYCLVWG-KTCSNKGNCWLYDTKSMRYALN------LSAAFFIFLGGFLNIAVWYHAKNLKIFDEEESSPKDSLKNKEVEMKTIDSNPE----------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VK84-1", "uniprot_id": "Q9VK84_DROME", "id": "Q9VK84-1", "name": "Solute carrier organic anion transporter family member", "aln": "------------------------------------------------MAEVKRR--------DPNRPP-----------------------------------------------------------------------------------GHYLCGMANWHPPWLQKYATTKMFMGVYGLLGTIQAMSYMYFIVTLTTLEKRFKIPSQTTGIILSGNEISQIMLSLILSYIGGQRNRPRWIAWGIVFCGLSCYILVLPHFIYGAGHEVLQFTKEYQDSLLNGTTGSDHSFQNISSVKTERLCGV-------------DKTEDDCDD-LFSYVPLVLIFLSQFVLGVGNTLYYSLGQTYLDDNTKKTNTPLMLAVAMALRMIGPVVGFFFGFISLNTFIDP----TKTPLIDSKDPRWLGAWWLGWVILGTLMCLFSGLIGLFPKQLPKVNASRTNSHLPLALRQTKEELKREENLSLSSRFSSNAALDTIGAAAGANADLPKLKDFPRALMRLLRNKLLIFNILSAVFYILGASGFMTFLTKYMEVQFHKDAQSATIIVGPISIMGMVVGLIGSGMVLSKKKPSVSKVLMWNVIVGGISILGQISYAFLYCPNTFS-----------MTQAGQLNLTSNCNMNCSCEGISYTPVCHEPTDTTFFSACHAGCRGY-NATS---KLYEDCSCVVNDPAPKSAAQRLLNLLQPTPEPELDTTTYFDEYLSGVPLLDDNGDFDDQLLSRTRRSTSDSVIRPGICTKN--CNWSFWAFSITSMIVSWFGSSGRVGNVLVNYRAVAHEDKSFAQGLALMMISLLALIPGPIIFGRLIDSTCLVWT-KTCNGNGNCQLYDQTRFRYSLN------FLSCLLTFMGLLFDYLVWYYGRNLDIYGDKEAKEEERANRKDQPITPLLAKKSEQE-------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9EPZ7-1", "uniprot_id": "SO1C1_RAT", "id": "Q9EPZ7-1", "name": "Solute carrier organic anion transporter family member 1C1", "aln": "------------------------------------------------MDTSSKENAHLFHKNSAQPAG-----------------------------------------------------------------------------------GPSFKAGYPSTEEARPCCGKLKVFLGALSFVYFAKALTEGYLKSTITQIERRFDIPSSLVGIIDGSFEIGNLLVITFVSYFGAKLHRPKIIGAGCLVMGFGTMLIAVPQFFMEKYS--YEKYERYSPSSNLTPNISPCYLESSSPSPRSIVGKS-------------QNKINDECEVDTSSSMWVYVFLGNLLRGLGETPIQPLGIAYLDDFASEDNAAFYIGCVQTVAIIGPIFGFLLGSLCAKLYVDIGFVNLDHITITPKDPQWVGAWWLGYLIAGFLSLLAAVPFWCLPKTLPRSQSRED-----SGSSSEKSKFITDDPVNYQMAPREESMKIME-----------MARDFLPSLKSLFRNPVYILYLCASTVQFNSLFGMVTYKPKYIEQQYGQSSSKANFVIGLINIPAVALGIFSGGIVMKKFRLGICEATKLYLGSSVFGYLLFLSLFALGCENSSVAGLTVSYQGTKPVSYHERALFSDCNSRCKCSDSKWEPMCGD-NGITYASACLAGCQSS-SRSGK-NIIFSNCTCVGFAAP-------------------------------------KSGNWS---------------GMMGRCQKDNGCSQMFLYFLVISVITSYTLSLGGIPGYILLLRCIQPQLKSFALGIYTLAVRVLAGIPAPVYFGVLIDTSCLKWGFKKCGSRGSCRLYDSHAFRHIYLGLTTLLGTVSVFLSTAVLLVLKKKYVSKRSSFITAREKIVMSSSVKKETCAARDHGLQPKYWPGKETRL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9ERB5-1", "uniprot_id": "SO1C1_MOUSE", "id": "Q9ERB5-1", "name": "Solute carrier organic anion transporter family member 1C1", "aln": "------------------------------------------------MDTSSKENAHLFHKNSAQPAG-----------------------------------------------------------------------------------GPSFTVGYPSTEEARPCCGKLKVFLGALSFVYFAKALAEGYLKSTVTQIERRFEIPSSLVGIIDGSFEIGNLLVITFVSYFGAKLHRPKIIGAGCLVMGFGTMLIAVPQFFMEKYS--YEKYERYSPSSNVTPSISPCYLESSSPSPSSILGKS-------------QNKISHECVGDSSSSMWVYVFLGNLLRGLGETPIQPLGIAYLDDFASEDNAAFYIGCVQTVAIIGPIFGFLLGSLCAKLYVDIGFVNLDHITITPKDPQWVGAWWLGYLIAGFLSLLAAVPFWCLPKTLPRSQSREN-----SGSTSEKSKFI-DDPIHYQMAPGDDKMKIME-----------MAKDFLPSLKTLFRNPVYILYLCASTVQFNSLFGMVTYKPKYIEQQYGQSSSKANFVIGLINIPAVALGIFSGGIVMKKFRLGICEATKLYLGSSVFGYLLFLSLFALGCENSSVAGLTVSYQGTKPVSYHERALFSDCNSRCKCSDSKWEPMCGD-NGITYVSACLAGCQSS-SRSGK-NIIFSNCTCVGFAAP-------------------------------------KSGNWS---------------GMMGRCQKDNGCSQMFLYFLVISVITSYTLSLGGIPGYILLLRCIQPQLKSFALGIYTLAVRVLAGIPAPVYFGVLIDTSCLKWGFKKCGSRGSCRLYDSHAFRHIYLGLTTLLGTVSVFLSMAVLFVLKKKYVSKHSSLITTREKIGMSSSIKKETCAARDRGLQPKYWPGKETRL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9NYB5-1", "uniprot_id": "SO1C1_HUMAN", "id": "Q9NYB5-1", "name": "Solute carrier organic anion transporter family member 1C1", "aln": "------------------------------------------------MDTSSKENIQLFCKTSVQPVG-----------------------------------------------------------------------------------RPSFKTEYPSSEEKQPCCGELKVFLCALSFVYFAKALAEGYLKSTITQIERRFDIPSSLVGVIDGSFEIGNLLVITFVSYFGAKLHRPKIIGAGCVIMGVGTLLIAMPQFFMEQY-----KYERYSPSSNSTLSISPCLLESSSQLPVSVMEKS-------------KSKISNECEVDTSSSMWIYVFLGNLLRGIGETPIQPLGIAYLDDFASEDNAAFYIGCVQTVAIIGPIFGFLLGSLCAKLYVDIGFVNLDHITITPKDPQWVGAWWLGYLIAGIISLLAAVPFWYLPKSLPRSQSRED-----SNSSSEKSKFIIDDHTDYQTPQGEN-AKIME-----------MARDFLPSLKNLFGNPVYFLYLCTSTVQFNSLFGMVTYKPKYIEQQYGQSSSRANFVIGLINIPAVALGIFSGGIVMKKFRISVCGAAKLYLGSSVFGYLLFLSLFALGCENSDVAGLTVSYQGTKPVSYHERALFSDCNSRCKCSETKWEPMCGE-NGITYVSACLAGCQTS-NRSGK-NIIFYNCTCVGIAAS-------------------------------------KSGNSS---------------GIVGRCQKDNGCPQMFLYFLVISVITSYTLSLGGIPGYILLLRCIKPQLKSFALGIYTLAIRVLAGIPAPVYFGVLIDTSCLKWGFKRCGSRGSCRLYDSNVFRHIYLGLTVILGTVSILLSIAVLFILKKNYVSKHRSFITKRERTMVSTRFQKENYTTSDHLLQPNYWPGKETQL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VVH9-1", "uniprot_id": "SO74D_DROME", "id": "Q9VVH9-1", "name": "Solute carrier organic anion transporter family member 74D", "aln": "MTKSNGDVEAAAQVQSLGGKPSNGHGQLNGNGYHQNGGRRDSSQAFTPLLSQHNNGTTNGEVTTPPPSTVLYESTPSNNNEWKAPEDLGHLKNGLGNILSSNNNGTGNGHSLSEKYAHEQAPLTGGYKLPPRSSESEESDFDSDLNGGSSAESSSSCGLFGCRPRWARRFASTHVFMVVFLLAYILQGMYMTYFVSVITTIEKLFQIKSKTTGILLSASEMGQICTAMLLTYFAGRGHRPRWIACGMVLFSIAAFSCALPHFIFGEQLMHSSVILQQTQVSPPNNSFSSHWLNASSEQVNPNLCILGGNQTHSGSECNEERQLEQASHSKITVIVLCIFFGSLLSSGIGQTAVATLGIPYIDDNVGSKQSPMYMAVTIGMRILGPASGFIFGSFCTRWYVNFS-----NPGFDATDPRWIGAWWLGPVAIGSLMLLASIAMFSFPKQLRGKQKPPG----------------QTATPAAPVEPEEK----------------PKLKDFPKTVRRQLSNDILMFRTASCVFHLLPIAGLYTFLPKYLETQFRLATYDANMIAAFCGILVMGIGIVISGLFILKRKPTARGVAAWIAFTALVYSAGMIILMFIGCSMNDFAG----YKPSDGNSPALIEPTCSAALNCTCDKENFAPICAD--GKMYISACHAGCSSSSLRPSDNRTLYSDCACIPDAPE----------------------------------------------------------AVNGYCDNN---CKNFIYFILIFAICVFMHSTSEVGSMLLVMRCTHPKDKAMAMGVIQSAIGLFGNVPCPIIYGAVVDSACLIWK-SVCGKHGACSLYDADTFRQYFLG------ITAGIMFLAFLMDLVVWRKAHRIDIAPEDPQEGGPASNGRTLEVSESKQPITPAPDTTV---", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . :: : : *: .:* :*: :.* :. *:: . ::. .: * ..: :**: :. * : :*: . : . : .* . : *:* : .** .*:** . . ::. :. : ::** *: :. .. . :: : **:*:****** : . : . . : :** * . *: :. * . :. . : : .**:* *: : :.: . : *:. .* .: : : . : : * . . * *. : *:* . : *** *** . :: .* *: * * : * * : . . :: *. . *: * *. ::. :* *: :* :.* ** * . * .* * *** :* . : . :: .: .: : ", "identical_positions": 76, "similar_positions": 145, "identity": "8.15%" }, { "cls_id": "homologset.agr.MGI:1889800", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "M0RCF7-1", "uniprot_id": "M0RCF7_RAT", "id": "M0RCF7-1", "name": "Myotilin", "aln": "MFNYERPKHFIQSQNPCGSGLQPPGPEVSSFPNQTKQSSIVIQPRQCTEQRFSASSTVSSHITVSSSAYPAS-QQLAGPNPGQKVTATYNQSPASFLSSILPSQPDYSNSKIPSTVDSNYQQSSVHQPVNAVSSQAAGAKPTPRTPDHEIQGSKEALIQDLERKLKCKDTLLHNGNQRLTYEEKMARRLLGPQNAAAVFQAQN-SDVQDSSQHNPEHARLQVPTSQVRSRSSSRADANDQDAIQEKFYPPRFIQVPENMSIEEGRFCRMDFKVSGLPAPDVSWYLNGRLVQSDELHKMIVSEKGFHSLIFEVVRASDAGPYACVARNRAGEATFTVQLDVLAKEHKRAPMFIYKPQSKKVFEGESVKLECQISAIPPPKLFWKRNNEMVQFNTDRISLYHDNAGRVTLLIKDVNKKDAGWYTVSAVNEAGVTTCNTRLDVTARPNQTPPAPKQLRVRPTFSKYLALNGKGLDVKQAFNPEGEFQRLAAQSGLYESEEL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9JIF9-1", "uniprot_id": "MYOTI_MOUSE", "id": "Q9JIF9-1", "name": "Myotilin", "aln": "MFNYERPKHFIQPQNPCGSRLQPPGPEVSGFPSQTKQSSIVIQPRQCTEQRFSASSTVSSHITVSSSAYPAP-QQLAGPNPGQKVTATYNQSPASFLSSILPSQPDYCNSKIPSTVDSNYQQSSVNQPVNAMSSQAANARPTPKTPDHEIQGSKEALIQDLERKLKCKDTLLHNGNQRLTYEEKMARRLLGPQNAAAVFQAQN-SDVQDSPQHNPEQARLHVPTSQVRSRSSSRAEANDQDAIQEKFYPPRFIQVPENMSIEEGRFCRMDFKVSGLPAPDVSWYLNGRPVQSDELHKMIVSEKGFHSLIFEVVRASDAGPYACVARNRAGEATFTVQLDVLAKEHKRAPMFIFKPQSKKVFEGETVKLECQISAIPPPKLFWKRNNEMVQFNTDRISLYHDNAGRVTLLIKDVNKKDAGWYTVSAVNEAGVTTCNTRLDVTARPIQTLPAPKQLRVRPTFSKYLALNGRGLDVKQAFNPEGEFQRLAAQSGLYESEEL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9UBF9-1", "uniprot_id": "MYOTI_HUMAN", "id": "Q9UBF9-1", "name": "Myotilin", "aln": "MFNYERPKHFIQSQNPCGSRLQPPGPETSSFSSQTKQSSIIIQPRQCTEQRFSASSTLSSHITMSSSAFPASPQQHAGSNPGQRVTTTYNQSPASFLSSILPSQPDYNSSKIPSAMDSNYQQSSAGQPINAKPSQTANAKPIPRTPDHEIQGSKEALIQDLERKLKCKDTLLHNGNQRLTYEEKMARRLLGPQNAAAVFQAQDDSGAQDSQQHNSEHARLQVPTSQVRSRSTSRGDVNDQDAIQEKFYPPRFIQVPENMSIDEGRFCRMDFKVSGLPAPDVSWYLNGRTVQSDDLHKMIVSEKGLHSLIFEVVRASDAGAYACVAKNRAGEATFTVQLDVLAKEHKRAPMFIYKPQSKKVLEGDSVKLECQISAIPPPKLFWKRNNEMVQFNTDRISLYQDNTGRVTLLIKDVNKKDAGWYTVSAVNEAGVTTCNTRLDVTARPNQTLPAPKQLRVRPTFSKYLALNGKGLNVKQAFNPEGEFQRLAAQSGLYESEEL", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "************.****** *******.*.*..*******:****************:*****:****:**. ** **.****:**:******************** .*****::********. **:** .**:*.*:* *:**********************************************************: *..*** ***.*:***:**********:**.:.************************:************************** ****:**********:**************.*****:**************************:*******:**::**********************************:**:***************************************** ** ********************:**:**************************", "identical_positions": 440, "similar_positions": 46, "identity": "88.35%" }, { "cls_id": "homologset.agr.MGI:1889802", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P29266-1", "uniprot_id": "3HIDH_RAT", "id": "P29266-1", "name": "3-hydroxyisobutyrate dehydrogenase, mitochondrial", "aln": "MAASLGFRGAASGLRYWSGRRRP-VGSLAAVCSRSMASKTPVGFIGLGNMGNPMAKNLIKHGYPLILYDVFPDVCKEFKEAGEQVASSPADVAEKADRIITMLPSSMNSIEVYSGANGILKKVKKGSLLIDSSTIDPSVSKELAKEVEKMGAVFMDAPVSGGVGAARSGNLTFMVGGVENEFAAAQELLGCMGSNVLYCGAVGSGQSAKICNNMLLAISMIGTAEAMNLGIRSGLDPKLLAKILNMSSGRCWSSDTYNPVPGVMDGVPSSNNYQGGFGTTLMAKDLGLAQDSATSTKTPILLGSVAHQIYRMMCSKGYSKKDFSSVFQYLREEETF-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q99L13-1", "uniprot_id": "3HIDH_MOUSE", "id": "Q99L13-1", "name": "3-hydroxyisobutyrate dehydrogenase, mitochondrial", "aln": "MAASLGFRGAASGLWYWSGRRRP-VGSLAAVCSRSMASKTPVGFIGLGNMGNPMAKNLMKHGYPLILYDVFPDVCKEFKEAGEQVASSPAEVAEKADRIITMLPSSMNAVEVYSGANGILKKVKKGSLLIDSSTIDPSVSKELAKEVEKMGAVFMDAPVSGGVGAARSGNLTFMVGGVEDEFAAAQELLECMGSNVVYCGAVGTGQSAKICNNMLLAISMIGTAEAMNLGIRSGLDPKLLAKILNMSSGRCWSSDTYNPVPGVMHGVPSSNNYQGGFGTTLMAKDLGLAQDSATSTKTPILLGSLAHQIYRMMCSKGYSKKDFSSVFQYLREEEPF-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P31937-1", "uniprot_id": "3HIDH_HUMAN", "id": "P31937-1", "name": "3-hydroxyisobutyrate dehydrogenase, mitochondrial", "aln": "MAASLRLLGAASGLRYWSRRLRPAAGSFAAVCSRSVASKTPVGFIGLGNMGNPMAKNLMKHGYPLIIYDVFPDACKEFQDAGEQVVSSPADVAEKADRIITMLPTSINAIEAYSGANGILKKVKKGSLLIDSSTIDPAVSKELAKEVEKMGAVFMDAPVSGGVGAARSGNLTFMVGGVEDEFAAAQELLGCMGSNVVYCGAVGTGQAAKICNNMLLAISMIGTAEAMNLGIRLGLDPKLLAKILNMSSGRCWSSDTYNPVPGVMDGVPSANNYQGGFGTTLMAKDLGLAQDSATSTKSPILLGSLAHQIYRMMCAKGYSKKDFSSVFQFLREEETF-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9V8M5-1", "uniprot_id": "3HIDH_DROME", "id": "Q9V8M5-1", "name": "3-hydroxyisobutyrate dehydrogenase, mitochondrial", "aln": "--MSLRVMSPAM-LNAWS-------QTLVRAMSTQGGAKN-IGFVGLGNMGANMASNLIKAGHKLHVFDISKPACDGLAAKGATVYAKTSELAKNSDFVITMLPN--NAIVDASYDEMTADGVNKDTIFIDSSTISPDLVKSLQKKISAKGARFIDAPVSGGVPGAEQATLTFMVGGTEAEYNAVKAVLECMGKKITHCGVYGMGQAAKLCNNMMLAISMIGVSEAMNLAVRQGLDANVFAEIINSSTGRCWASEIYNPVPGVCPSAPANRDYAGGFSSALITKDLGLASGVANASNSPIPLGSLAHKVYQSLCDKGLGNKDFSVVYDLMKKEKFSV", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ** . ..* * ** ::. . * . .:*. :**:****** **.**:* *: * ::*: .*. : * * :..:::*:::* :*****. *:: * : . *:*.:::******.* : *.* *::. ** *:******** .*....*******.* *: *.: :* ***.:: :**. * **:**:****:*******.:*****.:* ***.:::*:*:* *:****:*: ******* ..*: .:* ***.::*::******.. *.::::** ***:**::*: :* ** .:**** *:: :::*: ", "identical_positions": 147, "similar_positions": 110, "identity": "43.62%" }, { "cls_id": "homologset.agr.MGI:1889810", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P0C191-1", "uniprot_id": "GPVI_MOUSE", "id": "P0C191-1", "name": "Platelet glycoprotein VI", "aln": "MSPASPTFFCIGLCVLQVIQTQSGP-LPKPSLQAQPSSLVPLGQSVILRCQGPPDVDLYRLEKLKPEK----------YEDQDFLFIPTMERSNAGRYRCSYQNGSHWSLPSDQLELIATGVYAKPSLSAHPSSAVPQGRDVTLKCQSPYSFD--EFVLYKEGDTGSYKRPEKWY--RANFPIITVTAAHSGTYRCYSFSSSSP--------YLWSAPSDPLVLVVTGLSATPSQVPTEESFP---------VTE---SSRRPSILPTNKISTTEKPMNITASPEGLSPPFGFAHQHYAKGNLVRICLGATIIIILLGLLAEDWHSRKKCLQHRMRALQRPLPPLPLA------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "M0R8A3-1", "uniprot_id": "M0R8A3_RAT", "id": "M0R8A3-1", "name": "", "aln": "MSPASLTFFCIGLCVLQVIQAQHGP-LPKPSLQAQPSSLVPLGHPVTLRCLGPSDADLYRLEKVKPGKLI--------FIDQDFLFIPIMEINNAGRYRCSYQNESHWSLPSDQLELIATGVYSKPSLSAHPSSAIPPGRDVTLKCQSQYSFD--EFVLYKEGDTRPYKRPEKWY--RANFPVITVTAAHSGTYRCYSFSSSSP--------YLWSAPSDPLVVVVTGPSATPSQVPTEVPSP---------MTE---ASRRPSMLLTNKISTTEKPMNITVSPEGPSPPFGFAHQHYAKGNLVRICLGVMIIMFLVGFLAEDWHSRKKRLQHRIRAMQRPLPPLPLA------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9HCN6-1", "uniprot_id": "GPVI_HUMAN", "id": "Q9HCN6-1", "name": "Platelet glycoprotein VI", "aln": "MSPSPTALFCLGLCLGRVP-AQSGP-LPKPSLQALPSSLVPLEKPVTLRCQGPPGVDLYRLEKLSSSR----------YQDQAVLFIPAMKRSLAGRYRCSYQNGSLWSLPSDQLELVATGVFAKPSLSAQPGPAVSSGGDVTLQCQTRYGFD--QFALYKEGDPAPYKNPERWY--RASFPIITVTAAHSGTYRCYSFSSRDP--------YLWSAPSDPLELVVTGTSVTPSRLPTEPPSP---------VAEFSEATAELTVSFTNEVFTTETSRSITASPKESDSPAGPARQYYTKGNLVRICLGAVILIILAGFLAEDWHSRRKRLRHRGRAVQRPLPPLPPLPLTRKSNGGQDGGRQDVHSRGLCS", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M2BJF0-1", "uniprot_id": "A0A8M2BJF0_DANRE", "id": "A0A8M2BJF0-1", "name": "", "aln": "MGSSALPLLLLLISILHSGLTEDGRDLPRPALTVTPDSAVFTGETVNLKCVIESDHSDWTYEWYKDSNCVTLQSDGHYTVNRDTLTIRGAAESDQGQYWCKGVLG--WVSIQSSTVSLSVKDLPRSSVTVTPDSAVFTGGTVNLKCVIESDHSDWTYEWYKDRNSVKLQSDGHYTENRDTLTIRGAAESDQGQYWCKGQRSGRPNSSLSSSAVSLSVKALPTPTVTVGTSAAFTAETESSQSSSHVFLSVKDLKPMSELGSELGRNAAASLSSSSSSSSSLSSSSSSSPPPPGTPPLLVIGVSVGLSVFLLLLILLVLLLRHKKKGLYHVYDDVIKAENRNKGQSSLETLYVLN------------------", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*..:. .:: : :.: : :: * **:*:* . *.* * ..* *:* .. . : * . . :: * * . *:* *. * ... ::. .:.*::. *..*: * *.*:* ... : **: :. : :: * .:.: .: :..* * * . * * *. : * *..* *.: : . . . : . : .: ::... . *.. ..* : . * * :.: ::::* :* .. :. : . :* :* . ", "identical_positions": 47, "similar_positions": 113, "identity": "12.63%" }, { "cls_id": "homologset.agr.MGI:1889817", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q68H95-1", "uniprot_id": "REPI1_RAT", "id": "Q68H95-1", "name": "DNA-binding protein REPIN1", "aln": "MLERRCRGPTAMGPAHPWLFSGPSQESSQ----PNRGLRYQGKSVAQPGGPAPVKVHRCAHCRKRFPGWVALWLHTRRCQARLPLPCHECNQRFRHAPFLALHLQVHASAVPDLGFICHLCGHSFRGWVALVLHLRAHSASKRPITCPECNKRFWRQKQLRAHLRRCQPPAPEARPFICGNCGRSFAQWDQLVVHKRVHVAEALEEAAAKALGPRPRGRPSVTAPRPGGDAVDRPFQCACCGKRFRHKPNLIAHRRVHTGERPHQCPECGKRFTNKPYLTSHRRIHTGEKPYPCTECGRRFRHKPNLLSHSKIHKRSEVSAQAASHTGSHLIAAEP---MAQPALGVPLG------------SLRTPAEAPASLHSCTDCGRSFRLERFLRLHQRQHTGERPFTCTECGKNFGKKTHLVAHSRVHSGERPFACEECGRRFSQGSHLAAHRRDHAPERPFVCPDCGKAFRHKPYLAAHRRIHTGEKPYVCPDCGKAFSQKSNLVSHRRIHTGERPYACPDCDRSFSQKSNLITHRKSHIRDGAFCCAICGQTFDDEDRLLMHQKKHDA", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q5U4E2-1", "uniprot_id": "REPI1_MOUSE", "id": "Q5U4E2-1", "name": "DNA-binding protein REPIN1", "aln": "MLEQRCRGPTAMGPAQPWLFSGPSQESSQ----PDRGLRYQGKS-AQPRGQTPGKVHRCAHCRKRFPGWVALWLHARRCQARLPLPCHECNQRFRHAPFLALHLQVHASAVPDLGFICHLCGHSFRGWVALVLHLRAHSASKRPITCPECDRRFWRQKQLRAHLRRCQPPVPEARPFICGNCGRSFAQWDQLVVHKRVHVAEALEEAAAKALGPRPRGRP--AAPRPGGDAVDRPFQCACCGKRFRHKPNLIAHRRVHTGERPHQCPECGKRFTNKPYLTSHRRIHTGEKPYPCTECGRRFRHKPNLLSHSKIHKRLEVSAQAAPHPESHQIAAEP---MAQPALGVPLG------------SPRTPAEAPALLHSCSDCGRSFRLERFLRLHQRQHTGERPFACTECGKNFGKKTHLVAHSRVHSGERPFACEECGRRFSQGSHLAAHRRDHAPERPFVCPDCGKAFRHKPYLAAHRRIHTGEKPYVCPDCGKAFSQKSNLVSHRRIHTGERPYACPDCDRSFSQKSNLITHRKSHIRDGAFCCAICGQTFDDEDRLLMHQKKHDA", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9BWE0-3", "uniprot_id": "REPI1_HUMAN", "id": "Q9BWE0-3", "name": "DNA-binding protein REPIN1", "aln": "MLERRCRGPLAMGLAQPRLLSGPSQESPQTLGKESRGLRQQGTSVAQSGAQAPGRAHRCAHCRRHFPGWVALWLHTRRCQARLPLPCPECGRRFRHAPFLALHRQVHAAATPDLGFACHLCGQSFRGWVALVLHLRAHSAAKRPIACPKCERRFWRRKQLRAHLRRCHPPAPEARPFICGNCGRSFAQWDQLVAHKRVHVAEALEEAAAKALGPRPRGRPAVTAPRPGGDAVDRPFQCACCGKRFRHKPNLIAHRRVHTGERPHQCPECGKRFTNKPYLTSHRRIHTGEKPYPCKECGRRFRHKPNLLSHSKIHKRSEGSAQAAPGPGSPQLPAGPQESAAEPTPAVPLKPAQEPPPGAPPEHPQDPIEAPPSLYSCDDCGRSFRLERFLRAHQRQHTGERPFTCAECGKNFGKKTHLVAHSRVHSGERPFACEECGRRFSQGSHLAAHRRDHAPDRPFVCPDCGKAFRHKPYLAAHRRIHTGEKPYVCPDCGKAFSQKSNLVSHRRIHTGERPYACPDCDRSFSQKSNLITHRKSHIRDGAFCCAICGQTFDDEERLLAHQKKHDV", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "***:***** *** *:* *:*******.* .**** **.* **. . :* :.*******::**********:*********** **.:*********** ****:*.***** *****:*****************:****:**:*::****:**********:**.**********************.************************** :***********************************************************************.********************* * *****. . * :.* * *:*: .*** : * ***. *:** ************* ***********:*:*************************************************:***************************************************************************************************:*** ******.", "identical_positions": 471, "similar_positions": 45, "identity": "83.07%" }, { "cls_id": "homologset.agr.MGI:1889818", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q569A2-1", "uniprot_id": "TSN12_RAT", "id": "Q569A2-1", "name": "Tetraspanin-12", "aln": "---------MAREDSVKCLRCLLYALNLLFWLMSISVLAVSAWMRDYLNNVLTLTAETRVEEAVILTYFPVVHPVMIAVCCFLIIVGMLGYCGTVKRNLLLLAWYFGTLLVIFCVELACGVWTYEQEVMVPVQWSDMVTLKARMTNYGLPRYRWLTHAWNYFQREFKCCGVVYFTDW---------LEMTEMDWPPDSCCVREFPGCSKQAHQEDL--------------SDLYQEGCGKKMYSFLRGTKQLQVLRFLGISIGVTQILAMILTITLLWALYYDRREPGTDQMLSLKNDASQHLSCHSVELLKPS------------LSRIFEHTSMANSFNTHFEMEEL----------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8BKT6-1", "uniprot_id": "TSN12_MOUSE", "id": "Q8BKT6-1", "name": "Tetraspanin-12", "aln": "---------MAREDSVKCLRCLLYALNLLFWLMSISVLAVSAWMRDYLNNVLTLTAETRVEEAVILTYFPVVHPVMIAVCCFLIIVGMLGYCGTVKRNLLLLAWYFGTLLVIFCVELACGVWTYEQEVMVPVQWSDMVTLKARMTNYGLPRYRWLTHAWNYFQREFKCCGVVYFTDW---------LEMTEMDWPPDSCCVREFPGCSKQAHQEDL--------------SDLYQEGCGKKMYSFLRGTKQLQVLRFLGISIGVTQILAMILTITLLWALYYDRREPGTDQMLSLKNDTSQHLSCHSVELLKPS------------LSRIFEHTSMANSFNTHFEMEEL----------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O95859-1", "uniprot_id": "TSN12_HUMAN", "id": "O95859-1", "name": "Tetraspanin-12", "aln": "---------MAREDSVKCLRCLLYALNLLFWLMSISVLAVSAWMRDYLNNVLTLTAETRVEEAVILTYFPVVHPVMIAVCCFLIIVGMLGYCGTVKRNLLLLAWYFGSLLVIFCVELACGVWTYEQELMVPVQWSDMVTLKARMTNYGLPRYRWLTHAWNFFQREFKCCGVVYFTDW---------LEMTEMDWPPDSCCVREFPGCSKQAHQEDL--------------SDLYQEGCGKKMYSFLRGTKQLQVLRFLGISIGVTQILAMILTITLLWALYYDRREPGTDQMMSLKNDNSQHLSCPSVELLKPS------------LSRIFEHTSMANSFNTHFEMEEL----------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "O46101-1", "uniprot_id": "TSN2A_DROME", "id": "O46101-1", "name": "Tetraspanin-2A", "aln": "MGIGYGASDEQLEKQIGCVKYTLFCFNIVAWMISTALFALTVWLRAEPG----FNDWLRILEAQS---FYIGVYVLIGISIVMMAVSFLGCLSALMENTLALFVFVG-TQVFGFIAIVAGSAVLLQFSTINSSLQPLLNVSLRG-FVATSEYTYSNYVLTMIQENIGCCGATGPWDY---------LDLRQ---PLPSSCRDTVSG-------------------------NAFFNGCVDELTWFFEGKTGWIVA--LAMTLGLLNVICAVMSFVLVQAVKKEEEQASNYRR-------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q24188-1", "uniprot_id": "LBM_DROME", "id": "Q24188-1", "name": "Protein late bloomer", "aln": "-----------MGCATTSVKIASIVLNAVLGFLAAGAIGWIAYN-----------ADTETEEFVI---------AAYIACSLILVFALLGIFAAIRESVVLTATSAVFLLILAILQIVS-TCLFLHEFDVKSGRD-------------MVEVAWQANNMDSLQQKHECCGQSSAQDY---------IHLSLLIPPSCYADLQQTPD-------------------------HLYLDGCIEKVQSFYESDKLRFII--VSWVLVAFELICFALAVFLAISFKNKQRRMEF----------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q8IQK9-1", "uniprot_id": "Q8IQK9_DROME", "id": "Q8IQK9-1", "name": "", "aln": "---------MACCFNYKFVLNLCNFLFLICGLLLVVSGLYIFSDNKRILLSRLLAASSDRLSSLPQPLLFYIALGVAIAGFVATLAAVVGFWASCLHTYCFLTIYFLSVVVLLLTESVLCLAITLWPHCLGISLDETQMVRSLQSNYGVPGQEQFTNALDLAQVRFGCCGMRSSLDYDTSLWRLQGYGQRNWPVPLSCCFLKNAGHSMAYLDPKPANESMCQSLERLSYERERHTESCLPHLDNWYREQYSIFLGASLILAMIEFCVLLAIIMSCTGLASQRARLKKPVQEMRTQKVKSRQTLIENIYEPDVELRENSNHSGDGIYLGPASRHVSSEDFKELYIKPRDLYKQHNLRTSPANRPTQMRNYLV", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : : :: . . ..:* .: .. :: . : . * . *** *: * . . . :.* .: : . : : : :: : : . . ", "identical_positions": 8, "similar_positions": 39, "identity": "2.16%" }, { "cls_id": "homologset.agr.MGI:1889842", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZA02-1", "uniprot_id": "D3ZA02_RAT", "id": "D3ZA02-1", "name": "", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MACEIMP--------------------------------------------------------------------------------------------LRSSQEDERPLSPFYLSAHVSQVSSVSTTGELLERTIRSAVEEHLFDVNSSADQSSEDSEPGPSSASSTP-TRQRG--HQFKKQDDVWYGQDNLHFHSRELINKENIPCGLSSCDECILNSQEAERFQDDICEYVGERSKAKRQKSSSRLAELCENHDGHLSTESLSSMQTQETAEPEAVELRSSESKEAERSWRDTQHCESPAMKIQEHPS-------ISDTKQQRNQDDDDQQESFVPDLPQLDLTALCD-KTWEEPIP---SWQQENVESDEARLSPQAG-RLIHQLLDEDSDPMLSPRFYAYGQSRQYLDDTEVPPSPPNS--HSFM-RRRSSSLGSYDDEQEDLTPVQLTRRIQTLKKKIRKFEDRFEEERKYRPSHSDKAANPEVLKWTNDLAKFRKQLKETKLK-ISEEDLTPRTRQRSNTLPKSFGSQLEKEDEKKQELVDKAIRPSVEATLEGILRKLQEKRMESSRPEDIKDMTKDQIANEKVALQKALLYYESIHGRPVTKTERQIMKPLYDRYRLVKQILSRASTVPIIGSPSSKRRSPSLQPIIEGETASFFKEIKEQEEGSEDDSSTKPDFTVTLKTDSSAHCFLDQLEDDADGFISPMDDKMPSKCSQDSGLSNLHSASIPELLEYLQEIREEKKMIRKKLHDFEDNFFRQNGRNVQKEDR-TPMAEEYNEYKHIKAKLRLLEVLISKRDADSKSM", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8BGI4-1", "uniprot_id": "FA13A_MOUSE", "id": "Q8BGI4-1", "name": "Protein FAM13A", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MACEIMP--------------------------------------------------------------------------------------------LRSSQEDERPLSPFYLSAHVSQVSNVSTTGELLERTIRSAVEEHLFDVSNAGDQSSEDSEPGPSSASSIP-TRQRG--HQFKKQDDVWHGCD------KELINKENIPSGFSGCAECILNSQEAERFQDDICDYVGERSKPKRQKSSSRLAKLSDNHDGALSMESLSSMQSQETLEPEAAEPLSSESKEIERGGRDTQHCENPTMKIQEHPS-------LSDTKQQRNQDGEDQQESFVPDMPQLDLTALCDEKTWEEPIP---SWQPENADSDEARLSPQAG-RLIHQFLDEDSDPMLSPRFYAYGQSRQYLDDTEVPPSPPNS--HSFM-RRRSSSLGSYDDEQEDLTPVQLTRRIQTLKKKIRKFEDRFEEERKYRPSHSDKAANPEVLKWTNDLAKFRKQLKESKLK-ISEEDLTPRTRQRSNTLPKSFGSQLEKEDEKKQELLDKAIRPSVEATLEGILRKLQEKRVESSRPEDIKDMTKDQIANEKVALQKALLYYESIHGRPVTKTERQIMKPLYDRYRLVKQILSRASTVPIIGSPSSKRRSPSLQPIIEGETASFFKEIKEQEEGSEDDSSTKPDFAVTLKTDCSAHCFLDQLEDDADGFISPMDDKMPSKCSQDSGLSNLHSASIPELLEYLQEMREEKKMIRKKLHDFEDNFFRQNGRNVQKEDR-TPMAEEYNEYKHIKAKLRLLEVLISKRDSDSKSM", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O94988-4", "uniprot_id": "FA13A_HUMAN", "id": "O94988-4", "name": "Protein FAM13A", "aln": "-----------MGAGALAICQSKAAVRLKEDMKKIVAVPLNEQKDFTYQKLFGVSLQELERQGLTENGIPAVVWNIVEYLTQHGLTQEGLFRVNGNVKVVEQLRLKFESGVPVELGKDGDVCSAASLLKLFLRELPDSLITSALQPRFIQLFQDGRNDVQESSLRDLIKELPDTHYCLLKYLCQFLTKVAKHHVQNRMNVHNLATVFGPNCFHVPPGLEGMKEQDLCNKIMAKILENYNTLFEVEYTEN-----------------------------------------------------------------------DHLRCENLARLIIVKEVYYKNSLPILLTRGLERDMPKPPPKTKIPKSRSEGSIQAHRV------LQPELSDGIPQLSLRLSYRKACLEDMNSAEGAISAKLVPSSQEDERPLSPFYLSAHVPQVSNVSATGELLERTIRSAVEQHLFDVNNSGGQSSEDSESGTLSASSATSARQRR--RQSKEQDEVRHGRD------KGLINKENTPSGFNHLDDCILNTQEVEKVHKNTFGCAGERSKPKRQKSSTKLSELHDNQDGLVNMESLNSTRSHERTGPDDFEWMSDERKGNEKDGGHTQHFESPTMKIQEHPS-------LSDTKQQRNQDAGDQEESFVSEVPQSDLTALCDEKNWEEPIPAFSSWQRENSDSDEAHLSPQAG-RLIRQLLDEDSDPMLSPRFYAYGQSRQYLDDTEVPPSPPNS--HSFM-RRRSSSLGSYDDEQEDLTPAQLTRRIQSLKKKIRKFEDRFEEEKKYRPSHSDKAANPEVLKWTNDLAKFRRQLKESKLK-ISEEDLTPRMRQRSNTLPKSFGSQLEKEDEKKQELVDKAIKPSVEATLESIQRKLQEKRAESSRPEDIKDMTKDQIANEKVALQKALLYYESIHGRPVTKNERQVMKPLYDRYRLVKQILSRANTIPIIGSPSSKRRSPLLQPIIEGETASFFKEIKEEEEGSEDDSNVKPDFMVTLKTDFSARCFLDQFEDDADGFISPMDDKIPSKCSQDTGLSNLHAASIPELLEHLQEMREEKKRIRKKLRDFEDNFFRQNGRNVQKEDR-TPMAEEYSEYKHIKAKLRLLEVLISKRDTDSKSM", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AC58JWH4-1", "uniprot_id": "A0AC58JWH4_DANRE", "id": "A0AC58JWH4-1", "name": "", "aln": "MQPVRTVDVVDCSSFFCFSKHNKAAVQIKEDMKWMVQMPTIRAHPQR-RKMFTVSLLELRDLGLLEDEVPAVVRRLVEHLQKQGLRQEGLFRVNGSVRTVESLRQRFDGGEAVDLDQEVDTFAVASLLKQFFRDLPEGLIHQSIHKPLIQLYQESSEADFCHDLRELLRQLPDLHYSLLQYLCYFLSQVEQEHEHNRMTASNLATVFGPNVFHVSSGFDGIREQNICNNIMAKLIQNYSAVFESQLEEKQTEEESSNIIMVKEAKTNTESTEASLYTPVPQTQTPRVKKMKVTQCTPVENTDSSRKQLSPDNPASTPRKKKVTQCTTVDSADLSRENESGADDPTPTPRKKKVKKIKTEAMSRSIPQPTPSGDPVSRPSPHLPDRSSGAGDQFHLHSPDGSFSPSADSMNVTMSPARSTGTFNSPQEDERPISPFYISSEISPEHSRSDLTNFLEKTIRSAVEQHLFMH---AGQSSESSNPTLHSSSPATTARERR--RHQREQQESFRVEG----------DKENVPS------PGVRVTEDGDR-SLLLLPLTHELKKNKKPKHSPTLTELSDNQDTPASMEFQGPSGAYNRNATENME--SSDYRGNHVKDRSCTYFQTPAMKIQEALSGAEPCDDVPRLDLSTLTDDNNWADSCFFSASFLDFKNLLKSIGNDEPVPAYSSWQRESMDRDEARLSPHAGGKLIRQLLEEDSDPMVSPRFYGYGDGHQYLDDTEVPPSPPNA--HSFVSRRRSSSLGSCEDEREELTSAQLSKRIHVLKKKIRRYEEKFEEERKYRPSHGDKAGNPEVLRWMNELTRLRKDLKDHKLL-KSEEDLTPIPRQRSNTLPKSFGSQLEKKTPET-----KAPKPPVESTLETVTNKLQEKRKEAGRPEDIKDMTREQIGAEKVAIQKALLYYESIHGRPITKNERQVMKPLYDRYRLVKQILCRASAIPVIGSPSSKRRSPLLQPIIEGVPALFFSDTKEEEDGSDDD-DTRTQFTVTVKPELSMLGLLDQLDEDADGFISPVDELSPSKNTTDMRLSNLHAATMQELVEELQEAREEKKRIRKNLREFEDQFFKQNGRNVQKEDR-SPLAGEYNEYKHIKAKLRLLEVLISKQDS-SKFI", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q0E938-1", "uniprot_id": "Q0E938_DROME", "id": "Q0E938-1", "name": "FAM13A-like domain-containing protein", "aln": "-----------------------------------------------------------------------------MRHPTTGLNEDDLSRLTG------------SSSSTASCGSAASSSSSSSSSSSNPADRHEVVCSPEKPTPTGTDKSQLSSGFNSTYLPEIIHPAPEWQKSSRKRKERLDSTSAFGQDRKLQRSNSEELLTEP------------------AAIVSSTAQAAAELLE-------------------------------------------------------------------------------AQCEVIRR-------------------------------------------------------------------------------------------VSSEDFKRTASYANYRQEFEREQEECSELGENNASLANLPTGEAAKERPRLETSPARQAPKEASDDSECEHERRRSSERFCKSRQPPVRKSG---------VAKKVGGGSGSKYLPSRRDEQSAYKYDLSALKYERRGFISSRKQQQNQTQAMQSAADHNDNNLIDFHQQQKELQSKRSASISPTPTTSSSAGSDDSTPTSNAPAPIKAKPQ-----------RQQQSLDLTSAQESLPWERGDEPAPILSRRYAHSRPHIG----GNLDAAAKLAKVMPYPQ-----QLPKQASTVQLHSDITDMDCCLEPMDAVRAFSSLENMRTRDVMQQVLPAMMGAFQTPEDRVK--AINRRVTVLKKKLVQLEESLEQRLGYRPSQAERLNDKYMKNALAELSKLRKERHELKTDPIAALGLKVGSGGGAGIGGQEVAKKLER----------------MKATLAEIEQNLNEKRVNGHRSEQLEDLNADQLVQEKSAVQHGLLYFESLYGHPITKEERDAARPLYDRYRQLKRLVSRT---VMFGAGTG---IPELPTILEHEAMVFEATSTPLQYSSNNSTETTNSPSDSNAPNTLTQNASSDESTTTTTLTGPATGNSATSQENQAASENIAALSVDQLWEQLDRARDEKSLLKSTIREYESLFEEQNGRKMLKQDRRSLETETYAQYKEKKAKVRLLQALIKKHIGH----", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * : . * : .. . . * . . * : . .. : ..:..: . * *.* : :.:: . *: :. : . .: : . : . * . : . . .... *: . . * . :* . * ..* . . *:: * . *: .: * : . : . : :* ... .* * :..: : .: :*: : .: :. :.:*: ****: : *: :*:. ****:.:: : : . :*:::*:: :: * : .*. :. :....:**: :::** : .:*:*** :. *.*:::*:. :*: ** *:*:.***:**::*:*:** **: :******* :*:::.*: ::*: :. * * .*:* . * . : .*::. .. . : .: .: . : : .* .:. : .*: : :: :* * *:. *:**. ::..::::*. * .****:: *:** : : * :**. ***:***:.**.*: ", "identical_positions": 109, "similar_positions": 219, "identity": "9.63%" }, { "cls_id": "homologset.agr.MGI:1889844", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D4A7I8-1", "uniprot_id": "D4A7I8_RAT", "id": "D4A7I8-1", "name": "Formylglycine-generating enzyme", "aln": "MAAPAGEPAPRCCTGLAQVFLLLVL--ACGAAGSDEAEAGEGAVSLAGSCGCGTPQRAGAHGSSAA--------AQRYSREANAQGLTSGPRSLALTKMVPIPAGVFTMGTDDPQIKQDGEAPARRVTVDAFYMDAYEVSNADFEKFVNSTGYLTEAEKFGDSFVFEGMLSEPVKAQIHQA-VAAAPWWLPVKGADWRHPEGPDSTILHRSNHPVLHVSWNDAVAYCAWAGKRLPTEAEWEYSCRGGLQNRLFPWGNKLQPKGQHYANIWQGEFPVTNTGEDGFQGTAPVDAFPPNGYGLYNIVGNAWEWTSDWWTVHHSAEETLNPKGPTSGKDRVKKGGSYMCHKSYCYRYRCAARSQNTPDSSASNLGFRCAADHLPTAN", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8R0F3-1", "uniprot_id": "SUMF1_MOUSE", "id": "Q8R0F3-1", "name": "Formylglycine-generating enzyme", "aln": "MAAPAREPALRCCIRLARVFLLLVL--ACEVAGSDEAEAREGAASLAGSCGCGTPQRAGAHGSSAA--------AQRYSREANAPGLTSGPRPLALTKMVPIPAGVFTMGTDDPQIRQDGEAPARRVTVDGFYMDAYEVSNADFEKFVNSTGYLTEAEKFGDSFVFEGMLSEQVKTHIHQA-VAAAPWWLPVKGANWRHPEGPDSSILHRSNHPVLHVSWNDAVAYCTWAGKRLPTEAEWEYSCRGGLQNRLFPWGNKLQPKGQHYANIWQGKFPVSNTGEDGFQGTAPVDAFPPNGYGLYNIVGNVWEWTSDWWTVHHSVEETFNPKGPTSGKDRVKKGGSYMCHKSYCYRYRCAARSQNTPDSSASNLGFRCAADHLPTAD", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8NBK3-1", "uniprot_id": "SUMF1_HUMAN", "id": "Q8NBK3-1", "name": "Formylglycine-generating enzyme", "aln": "MAAPALGLVCGRCPELGLVLLLLLLSLLCGAAGSQEAGTGAGAGSLAGSCGCGTPQRPGAHGSSAA--------AHRYSREANAPGPVPGERQLAHSKMVPIPAGVFTMGTDDPQIKQDGEAPARRVTIDAFYMDAYEVSNTEFEKFVNSTGYLTEAEKFGDSFVFEGMLSEQVKTNIQQA-VAAAPWWLPVKGANWRHPEGPDSTILHRPDHPVLHVSWNDAVAYCTWAGKRLPTEAEWEYSCRGGLHNRLFPWGNKLQPKGQHYANIWQGEFPVTNTGEDGFQGTAPVDAFPPNGYGLYNIVGNAWEWTSDWWTVHHSVEETLNPKGPPSGKDRVKKGGSYMCHRSYCYRYRCAARSQNTPDSSASNLGFRCAADRLPTMD", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F1QHA4-1", "uniprot_id": "F1QHA4_DANRE", "id": "F1QHA4-1", "name": "Formylglycine-generating enzyme", "aln": "MAMAP-------VLNICVVLFFSILAVSCDVGDIVQEQRSESPESQGTDCGCQGLKREVSVGVSDVNTLDHHDDANIYSKTANEG--PDKTESDVRSKLVLLQGGWFLMGTDDPGIPQDGEGPQRKVKLDAFYIEEHEVTNQQFQHFTNQTGYITEAERFGDSFVFEGLLSEEVKSTLSHA-VAAAPWWSPVKGADWRHPEGPDSTIHNRMNHPALHVSWDDARAYCQWAKRRLPTEAEWELACRGGLQDRMYPWGNKLMPRGQHYANLWQGDFPNHNTAEDGYANTSPVMSFPANGFGLYDMVGNAWEWTADWWTVHHSAEDKFNPKGPESGTDRVKKGGSYMCHKSYCYRYRCAARSQNTPDSSASNLGFRCASDVDP---", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9W0U6-1", "uniprot_id": "Q9W0U6_DROME", "id": "Q9W0U6-1", "name": "Sulfatase-modifying factor enzyme-like domain-containing protein", "aln": "------------MTTIILVLFIWIVLFNDVSSDCGCQKLDRKAPDMPSISGQVCQQR--AQG------------AHSHYRD------YYGELEPNIADMSLLPGGTVYMGTDKPHFPADREAPERQVKLNDFYIDKYEVSNEAFAKFVLHTNYTTEAERYGDSFLFKSLLSPLEQKNLEDFRVASAVWWYKVAGVNWRHPNGVDSDIDHLGRHPVVHVSWRDAVEYCKWAGKRLPSEAEWEAACRGGKERKLFPWGNKLMPRNEHWLNIWQGDFPDGNLAEDGFEYTSPVDAFRQNIYDLHNMVGNVWEWTADLWDVNDVSD---NP-------NRVKKGGSYLCHKSYCYRYRCAARSQNTEDSSAGNLGFRCAKNA-----", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : *::: :: .. . . .* :* : * *: : : :.: : .* . ****.* : * *.* *:*.:: **:: :**:* * :*. *.* ****::****:*:.:** : : . **:* ** * *.:****:* ** * : **.:**** ** ** ** :***:***** :**** . :::****** *:.:*: *:***.** * .***: *:** :* * :.*:::***.****:* * *:. : ** :********:**:*************** ****.******* : ", "identical_positions": 147, "similar_positions": 84, "identity": "38.38%" }, { "cls_id": "homologset.agr.MGI:1889850", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9Z2D3-1", "uniprot_id": "GSDME_MOUSE", "id": "Q9Z2D3-1", "name": "Gasdermin-E", "aln": "MFAKATRNFLKEVDAGGDLISVSHLNDSDKLQLLSLVTKKKRYWCWQRPKYQILSATLEDVLTEG-HCLSPVVVESDFVKYESKCENHKSGAIGTVVGKVKLNVGGKGVVESHSSFGTLRKQEVDVQQLIQDAVKRTVNMDNLVLQQVLESRNEVLCVLTQKIMTTQKCVISEHVQSEETCGGMVGIQTKTIQVSATEDGTVTTDTNVVLEIPAATTIAYGIMELFVKQDGQFEFCLLQGKHGGFEHERKLDSVYLDPLAYREFAFLDMLDGGQGISSQDGPLRVVKQATLHLERSFHPFAVLPAQQQRALFCVLQKILFDEELLRALEQVCDDVAGGLWSSQAVLAMEELTDSQQQDLTAFLQLVGYR------------------------------IQGEHPGPQDEVSNQK------------LFATAYFLVSALAEMPDNATVFLGTCCKLHVISSLCCLLHALSDDSVCDFHNPTLAPLRDTERFGIVQRLFASADIALERMQFSAKATILKDSCIFPLILHITLSGLSTLSKEHEEELCQSG-HATGQD", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "F1MAG0-1", "uniprot_id": "F1MAG0_RAT", "id": "F1MAG0-1", "name": "", "aln": "MFAKATRNFLKEVDAGGDLISVSHLNDSDKLQLLSLVTKKKRYWCWQRPKYQFLSATLGDVLTEG-HCLSPVVVESDFVKYESKCENHKSGTIGTVMGKVKLNVGGKGLVESQSSFGTLRKQEVDVQQLIQDAVGRTVNLDSLVLQQVLESRNEVLCVLTQKIVTTQKCVISEHVQSEETCGGMVGIQTKIVQVSAMEDGTITTDTNVMLEIPAATTIAYGIMELYVKKDGQFEFCLLQGKHGGFEQERKVDSVYLDPLAYREFAFLDMPDGGQGISSQDGPLRVLKQATLHLERSFRSFAVLPAQQQMALFCILQKILFDEELLRALEQVCDDVAGGLWSSQAILAMEELTGSQQQDLTAFLKLVGYR------------------------------VQGEHPGPQDEVSNQK------------LFATAYFLVSALAEMPDNATVFLGTCCKLHVIPSLCHLLHALSDDSVCDFQDPTLAPLRDTERFGIVQRLFASADIALERMQFSAKATILKDSCMFPLILHITLSGLYTLSKEHEEHLFQSEVHATSQD", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O60443-1", "uniprot_id": "GSDME_HUMAN", "id": "O60443-1", "name": "Gasdermin-E", "aln": "MFAKATRNFLREVDADGDLIAVSNLNDSDKLQLLSLVTKKKRFWCWQRPKYQFLSLTLGDVLIED-QFPSPVVVESDFVKYEGKFANHVSGTLETALGKVKLNLGGSSRVESQSSFGTLRKQEVDLQQLIRDSAERTINLRNPVLQQVLEGRNEVLCVLTQKITTMQKCVISEHMQVEEKCGGIVGIQTKTVQVSATEDGNVTKDSNVVLEIPAATTIAYGVIELYVKLDGQFEFCLLRGKQGGFENKKRIDSVYLDPLVFREFAFIDMPDAAHGISSQDGPLSVLKQATLLLERNFHPFAELPEPQQTALSDIFQAVLFDDELLMVLEPVCDDLVSGLSPTVAVLG--ELKPRQQQDLVAFLQLVGCS------------------------------LQGGCPGPEDAGSKQ-------------LFMTAYFLVSALAEMPDSAAALLGTCCKLQIIPTLCHLLRALSDDGVSDLEDPTLTPLKDTERFGIVQRLFASADISLERLKSSVKAVILKDSKVFPLLLCITLNGLCALGREHS--------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "E7F9U2-1", "uniprot_id": "E7F9U2_DANRE", "id": "E7F9U2-1", "name": "", "aln": "MFEIATKKFVRHIDPSGVLIPASSLNDSKNLQLLAVVLKSKKRWFWQRIKYRPTEFTLNNLLKEKKTQLKPEYKKEEFVKYMETNRNVLGGSVDVSGPDVTLNLNGRSISNLYLRLGRLQKEYLDIPKLLNDTRGRKLDLKHSLIKQSK-NKNKTFAILKERIFTTCNGKINWNEEEKSGCQTVFTVFWNKMSIEGS--GKQHHGSETKLDIPPDTVLAYSVMEISIDAEGCFELCLFPRGLG------------TDETSEIPSPVPSEVDGQFPLMQEGFPLHTQKKALADVQTCFCALADLSVELRFSILVLLRKIMLDRTILSALVDTLETLSS---DEAPCFLTKELSEKQSQIIREFLHLLKWESHENNQYPTSTSLSITNGCQKSTANHSHPVMASDQNGGHSAKSNQNGCSKAASKPSMELMYAMQMLLCALEELTDAGLKLLEPFCTSEHLSSLQDLVIHLTS-IMPLCKNTVPVSLQNEDEFHRKEELFKSCNVLLKKENDSLTSEVTCSVGFLPLVLCIAIHGLASLSAV----------------", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "** **::*::.:*..* **..* ****.:****::* *.*: * *** **: . ** ::* * .* :.:**** . * .*:: . .*.**:.* . : :* *:*: :*: :*:.*: *.::: :::* .:*:.:.:*.::* * : *. : : :. * :. : : :.:.. *. .::. *:**. *.:**.::*: :. :* **:**: * * .. . *. : .:. ** . *:* :: * .:* *. : :: ::: :::* :* .* . : : . . : **. *.* : **:*: : . * .. *:* *: : :*:.** *:.* . :* . *. . :.:* *: *:. : .:.. ..*:: :.* :.** *.:: *:: : * .: : . .:**:* *:: ** :*. ", "identical_positions": 117, "similar_positions": 184, "identity": "21.04%" }, { "cls_id": "homologset.agr.MGI:1890077", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "G3V7R4-1", "uniprot_id": "FOXO1_RAT", "id": "G3V7R4-1", "name": "Forkhead box protein O1", "aln": "MAEAPQ--VVETDPDFEPLPRQRSCTWPLPRPEFNQ---SNSTTSSPAPSGSTAANPDATASL--ASASAVSTDFMSNLSLLEESEDFARAPG----CVAVAAAAAASRGLCGDFQGPEAGCVHSAPPQPPPTGP----LSQPPPVPP---AAAGPLAGQPRKTSSSRRNAWGNLSYADLITKAIESSAEKRLTLSQIYEWMVKSVPYFKDKGDSNSSAGWKNSIRHNLSLHSKFIRVQNEGTGKSSWWMLNPEGGKSGKSPRRRAASMDNNSKFAKSRGRAAKKKASLQSG--------QEGPGDSPGSQFSKWPASPGSHSNDDFDNWSTFRPRTSSNASTISGRLSPIMTEQDDLGDGDVHSLVYPP--SAAKMASTLPSLSEISN------PEN-MENLLDNLNLLSSPTSLT-----VSTQSSPGSMMQQTPCYS-FAPPNTSLN--SPSPNYAKYTYGQSSMSPVPQMPMQTLQDSKSSYGGLN----QYNCAPGLLKELLTSDSPPHNDIMSPVDPGVAQPNSRVLGQNVLMGPNSVMPAYGSQAPHNKMMNPSSHTHPGHAQQTSSVNGRALPHVVNTMPHTSAMNRLTPVKTPLQVPLSHPMQMSALGNYSSVSSCNGYGR-------MGVLHQEKLPSDLDGMFIER----LDCDMESIIRNDLMDGDTLDFNFDNVLPNQ----SFP-HSVKTTTHSWVSG", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9R1E0-1", "uniprot_id": "FOXO1_MOUSE", "id": "Q9R1E0-1", "name": "Forkhead box protein O1", "aln": "MAEAPQ--VVETDPDFEPLPRQRSCTWPLPRPEFNQ---SNSTTSSPAPSGGAAANPDAAASL--ASASAVSTDFMSNLSLLEESEDFARAPG----CVAVAAAAAASRGLCGDFQGPEAGCVHPAPPQPPPTGP----LSQPPPVPPSAAAAAGPLAGQPRKTSSSRRNAWGNLSYADLITKAIESSAEKRLTLSQIYEWMVKSVPYFKDKGDSNSSAGWKNSIRHNLSLHSKFIRVQNEGTGKSSWWMLNPEGGKSGKSPRRRAASMDNNSKFAKSRGRAAKKKASLQSG--------QEGPGDSPGSQFSKWPASPGSHSNDDFDNWSTFRPRTSSNASTISGRLSPIMTEQDDLGDGDVHSLVYPP--SAAKMASTLPSLSEISN------PEN-MENLLDNLNLLSSPTSLT-----VSTQSSPGSMMQQTPCYS-FAPPNTSLN--SPSPNYSKYTYGQSSMSPLPQMPMQTLQDSKSSYGGLN----QYNCAPGLLKELLTSDSPPHNDIMSPVDPGVAQPNSRVLGQNVMMGPNSVMPAYGSQASHNKMMNPSSHTHPGHAQQTASVNGRTLPHVVNTMPHTSAMNRLTPVKTPLQVPLSHPMQMSALGSYSSVSSCNGYGR-------MGVLHQEKLPSDLDGMFIER----LDCDMESIIRNDLMDGDTLDFNFDNVLPNQ----SFP-HSVKTTTHSWVSG", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q12778-1", "uniprot_id": "FOXO1_HUMAN", "id": "Q12778-1", "name": "Forkhead box protein O1", "aln": "MAEAPQ--VVEIDPDFEPLPRPRSCTWPLPRPEFSQ---SNSATSSPAPSGSAAANPDAAAGLPSASAAAVSADFMSNLSLLEESEDFPQAPGSVAAAVAAAAAAAATGGLCGDFQGPEAGCLHPAPPQPPPPGP----LSQHPPVPP---AAAGPLAGQPRKSSSSRRNAWGNLSYADLITKAIESSAEKRLTLSQIYEWMVKSVPYFKDKGDSNSSAGWKNSIRHNLSLHSKFIRVQNEGTGKSSWWMLNPEGGKSGKSPRRRAASMDNNSKFAKSRSRAAKKKASLQSG--------QEGAGDSPGSQFSKWPASPGSHSNDDFDNWSTFRPRTSSNASTISGRLSPIMTEQDDLGEGDVHSMVYPP--SAAKMASTLPSLSEISN------PEN-MENLLDNLNLLSSPTSLT-----VSTQSSPGTMMQQTPCYS-FAPPNTSLN--SPSPNYQKYTYGQSSMSPLPQMPIQTLQDNKSSYGGMS----QYNCAPGLLKELLTSDSPPHNDIMTPVDPGVAQPNSRVLGQNVMMGPNSVMSTYGSQASHNKMMNPSSHTHPGHAQQTSAVNGRPLPHTVSTMPHTSGMNRLTQVKTPVQVPLPHPMQMSALGGYSSVSSCNGYGR-------MGLLHQEKLPSDLDGMFIER----LDCDMESIIRNDLMDGDTLDFNFDNVLPNQ----SFP-HSVKTTTHSWVSG", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A3RK74-1", "uniprot_id": "FX1AA_DANRE", "id": "A3RK74-1", "name": "Forkhead box protein O1-A", "aln": "MADAAQNQMVEIDPDFEPLSRPRSCTWPLPRPEFPNPAAADSNTSSPAPS----VKQEP----------SSTADFINNLSLLEENEDYPDQKP---------------LMLCSEFQCQEN-CIHQQQIPSQQ--------QQVPVLSSPVAAAAAAAAAAQRKSSSSRRNAWGNMSYADLITKAIESSPEKRLTLSQIYDWMVKSVPYFKDKGDSNSSAGWKNSIRHNLSLHSRFIRVQNEGTGKSSWWMLNPEGGKSGKSPRRRAASMDNNSKFAKSRGRAAKKKLALQGG--------PEGGADSPGSQYGKWPGSPNSHSNDDFEAWTAFRPRTSSNASTLSGRLSPFIDDEL--GDSDVH-MVYPGPGSGTKMTSTLPSLSEMAGSLGHSGSENVMENLLDNLNLLSPKNPSTGGPGSGSNQSSPSSLMQASPGYSPYSSPGLSAVSQQTQQDFRKCLYGQAGMGSMSPMPMQPLPESKPSFGPGGGTMGQFNCTAGLLKELLTSDGEP-GDLMPSVDTVVSQSAGGSGCMLPPYSSGRNELMGG-GPTHSHTLSHPHNMHGQAPPTSVALNGRSLHPLT-AIGHSSVGGRLGSGKSPMQMQYGGSGHLGGGLPPYCSMSSNGYGRGPGMMAHQQLQHLEKLPSDLDGMPIER----FECDVESILHDTLMDGESLDFNFDPMNSQQ----GFVPHSVKTTTHSWVSG", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A3RK75-1", "uniprot_id": "FX1AB_DANRE", "id": "A3RK75-1", "name": "Forkhead box protein O1-B", "aln": "MAEPQQ-QLVDIDPDFEPLSRPRSCTWPLHRPEFSE-QPGNSNTSSPAPS----VKPE-----------QGIVDFINSLSLLEETEDYPDEKP---------------VLLN-DFHCQDN-CAHPQQQHPQQPNPQLTHPQQVPPLPAP--ASGSSPAAAQRKSSSSRRNAWGNMSYADLITKAIESSPEKRLTLSQIYEWMVKSVPYFKDKGDSNSSAGWKNSIRHNLSLHSRFVRVQNEGTGKSSWWMLNPEGGKSGKSPRRRATSMDNNSKFTKSRGRAAKKKMSLQGG--------LDGGSNSPGSQYPKWLGSPNSHSNDDFEPWGNFRTRASSDASTLSGRRSPFLPEED--EAAEVH-IGYPG----TKLGGPLPSLSEVAG---HHGSENMMDNLLENLNLISPKNNTQGSQEAQTALSSP--LMQGSPGYPSYTSPNMGPQ-PQVQQDYRKCLYGQGGVGGLNPISIPTLSDSKP--GGYGPFVGQYNCAPGLLKELLTADADPRGELMQ---------SGEGQPVLPSYASQGQMAQGGKMITHPHLHAHPRSLH-QLPSPAMGLNGCAMLPH----GHPVRLSSMKPQPHLPHHTHLGRGGGEAGMPSYT--NGNGFHR-HGAIAHHHHSHPERLPSDLDDMLIDQLD--VECDVERVLHDTLMDGDALDFNFDPMSSQQ----SFT-HSVKTSTHNWVSG", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q95V55-1", "uniprot_id": "FOXO_DROME", "id": "Q95V55-1", "name": "Forkhead box protein O", "aln": "----------MMDGYAQEWPRLTHTDNGLAMDQLGG-------------------------------------DLPLDVGFEPQTRARSNTWP---------------------CPRPENFVEPTDELDSTKASN-----QQLAPGDS----QQAIQNANAAKKNSSRRNAWGNLSYADLITHAIGSATDKRLTLSQIYEWMVQNVPYFKDKGDSNSSAGWKNSIRHNLSLHNRFMRVQNEGTGKSSWWMLNPEAK-PGKSVRRRAASMET-SRYEKRRGRAKKRVEALRQAGVVGLNDATPSPSSSVSEGLDHFPESP-LHSGGGFQLSPDFRQRASSNASSCG-RLSPIR--AQDLEPDWGFPVDYQN---TTMTQAHAQALEELTG------------TMADELTLCNQQQQGFSAASGLPSQPPPPPYQPPQHQQAQQQQQQQSPYALNGPASGYNTLQPQSQCLLHRSLNCSCMHNARDGLSPNSVTTTMSPAYPNSEPSSDSLNTYSNVVLDGPADTAALMVQQQQQQQQQQQLSASLEGQCLEVLNNEAQPIDEFNLENFPVGNLECNVEELLQQEMSYGGLLDINIPLATVNTNLVNSSSGPLSISNISNLSNISSNSGSSLSLNQLQAQLQQQQQQQQAQQQQQAQQQQQQHQQHQQQLLLNNNNNSSSSLELATQTATTNLNARVQYSQPSVVTSPPSWVH-", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * : .* * :: *: .:.: :.. . : . .* . . . . *..*********:*******:** *:.:*********:***:.***************************.:*:******************. .*** ****:**:. *:: * *.** *: :*: . . ..* .. :: ** **...*: ** *:**:**: . * **: . : * : . :*.*::. .: ::*.* . . ..* . . . . : *. : : : : . . . .. . : : . : . : . : : . .* : :: :: : :: : : : ::.: ...:*:: : .: : ** *:. .** ", "identical_positions": 129, "similar_positions": 134, "identity": "18.12%" }, { "cls_id": "homologset.agr.MGI:1890081", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZBQ1-1", "uniprot_id": "D3ZBQ1_RAT", "id": "D3ZBQ1-1", "name": "", "aln": "MAEAPASPVP------------LSPLEVELDPEFEPQSRPRSCTWPLQRPELQASPAKPSGETAADSMIPEEDDDEDDEDSGGRGSSAMVIGGG-VSSALGSGLLLEDSARLLSPGGQDLGTGPASSAGALSGGTQTQLQPQQPLPPPQPGAAGGSGQPRKCSSRRNAWGNLSYADLITRAIESSPDKRLTLSQIYEWMVRCVPYFKDKGDSNSSAGWKNSIRHNLSLHSRFMRVQNEGTGKSSWWIINPDGGKSGKAPRRRAVSMDNSNKYTKSRGRAAKKKAALQAA---------PESADDSPSQLSKWPGSPTSRSSDELDAWTDFRSRTNSNASTVSGRLSPILASTELDDVQDDDGPLSPMLYSSSASLSPSVSKPCTVELPRLTDMAGTMNLNDGLAENLMDDLLDNIALPPSQASPPGGLMQRSSSFPYTAKSSGLGSPTSSFNSTVFGPASLNSLR-----QSPMQTIQENRPATFSSVSHYGNQTLQDLLTSDSLSHSDVMMTQSDPLMSQASTAVSAQNARRNVMLRNDPMMSFAAQPTQGSLVNQNLLHHQHQTQGALGGSRALSNSVSNMGLSDSSSLGSAKHQQQSPVSQSMQTLSDSLSGSSLYSASANLPVMGHDKFPSDLDLDMFNGSLECDMESIIRSELMDADGLDFNFDSLISTQNVVGLNVGNFTGAKQASSQSWVPG", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9WVH4-1", "uniprot_id": "FOXO3_MOUSE", "id": "Q9WVH4-1", "name": "Forkhead box protein O3", "aln": "MAEAPASPVP------------LSPLEVELDPEFEPQSRPRSCTWPLQRPELQASPAKPSGETAADSMIPEEDDDEDDEDGGGRASSAMVIGGG-VSSTLGSGLLLEDSAMLLAPGGQDLGSGPASAAGALSGGTPTQLQPQQPLPQPQPGAAGGSGQPRKCSSRRNAWGNLSYADLITRAIESSPDKRLTLSQIYEWMVRCVPYFKDKGDSNSSAGWKNSIRHNLSLHSRFMRVQNEGTGKSSWWIINPDGGKSGKAPRRRAVSMDNSNKYTKSRGRAAKKKAALQAA---------PESADDSPSQLSKWPGSPTSRSSDELDAWTDFRSRTNSNASTVSGRLSPILASTELDDVQDDDGPLSPMLYSSSASLSPSVSKPCTVELPRLTDMAGTMNLNDGLAENLMDDLLDNIALPPSQPSPPGGLMQRGSSFPYTAKSSGLGSPTGSFNSTVFGPSSLNSLR-----QSPMQTIQENRPATFSSVSHYGNQTLQDLLASDSLSHSDVMMTQSDPLMSQASTAVSAQNARRNVMLRNDPMMSFAAQPTQGSLVNQNLLHHQHQTQGALGGSRALSNSVSNMGLSDSSSLGSAKHQQQSPASQSMQTLSDSLSGSSLYSASANLPVMGHDKFPSDLDLDMFNGSLECDMESIIRSELMDADGLDFNFDSLISTQNVVGLNVGNFTGAKQASSQSWVPG", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O43524-1", "uniprot_id": "FOXO3_HUMAN", "id": "O43524-1", "name": "Forkhead box protein O3", "aln": "MAEAPASPAP------------LSPLEVELDPEFEPQSRPRSCTWPLQRPELQASPAKPSGETAADSMIPEEEDDEDDEDGGGRAGSAMAIGGGGGSGTLGSGLLLEDSARVLAPGGQDPGSGPATAAGGLSGGTQALLQPQQPLPPPQPGAAGGSGQPRKCSSRRNAWGNLSYADLITRAIESSPDKRLTLSQIYEWMVRCVPYFKDKGDSNSSAGWKNSIRHNLSLHSRFMRVQNEGTGKSSWWIINPDGGKSGKAPRRRAVSMDNSNKYTKSRGRAAKKKAALQTA---------PESADDSPSQLSKWPGSPTSRSSDELDAWTDFRSRTNSNASTVSGRLSPIMASTELDEVQDDDAPLSPMLYSSSASLSPSVSKPCTVELPRLTDMAGTMNLNDGLTENLMDDLLDNITLPPSQPSPTGGLMQRSSSFPYTTKGSGLGSPTSSFNSTVFGPSSLNSLR-----QSPMQTIQENKPATFSSMSHYGNQTLQDLLTSDSLSHSDVMMTQSDPLMSQASTAVSAQNSRRNVMLRNDPMMSFAAQPNQGSLVNQNLLHHQHQTQGALGGSRALSNSVSNMGLSESSSLGSAKHQQQSPVSQSMQTLSDSLSGSSLYSTSANLPVMGHEKFPSDLDLDMFNGSLECDMESIIRSELMDADGLDFNFDSLISTQNVVGLNVGNFTGAKQASSQSWVPG", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q95V55-1", "uniprot_id": "FOXO_DROME", "id": "Q95V55-1", "name": "Forkhead box protein O", "aln": "MMDGYAQEWPRLTHTDNGLAMDQLGGDLPLDVGFEPQTRARSNTWPCPRPENFVEPTDELDSTKAS--------------------------------------------------------------------------NQQLAPGDSQQAIQNANAAKKNSSRRNAWGNLSYADLITHAIGSATDKRLTLSQIYEWMVQNVPYFKDKGDSNSSAGWKNSIRHNLSLHNRFMRVQNEGTGKSSWWMLNP-EAKPGKSVRRRAASMETS-RYEKRRGRAKKRVEALRQAGVVGLNDATPSPSSSVSEGLDHFPESP-LHSGGGFQLSPDFRQRASSNASSCG-RLSPIRAQDLEPDWGFPVDYQNTTMTQAHAQALEELTGTMADELTLCNQQQQGFSAASGLPSQPPPPPYQ-----PPQHQQAQQQQQQQSPYALNGPASGYNTLQPQSQCLLHRSLNCSCMHNARDGLSPNSVTTTMSPAYPNSEPSSDSLNTYSNVVLDGPADTAALMVQQQ-QQQQQQQQLSASLEGQCLEVLNNEAQPIDEFNLENFPVGNLECNVEELLQQEMSYGGLLDINIPLATVNTNLVNSSSGPLSISNISNLSNISSNSGSSLSLNQLQAQLQQQQQQQQAQQQQQAQQQQQQHQQHQQQLLLNNNNNSSSSLELATQTATTNLN-ARVQYSQPSVVTSPPSWVH-", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* :. *. * :: ** ****:*.** *** *** ..*:. ..* *. ** * . * .:. .:* *****************:** *:.**************: ***************************.****************::** .*.**: ****.**:.* :* * **** *: **: * *..:.. .. *.::* ** :*.. :: .***.*:.****: . ***** *. : .. : .: *. .:: . : **. .: :. .**..: : *.* . . *: *.:. . .** .: . :. :. . . ..:: ** .. ** .* . .. . . :. *. :.: .:*.*.: .* . :**. : : : *: .: :. *.: : :. * :. . *. .:. :. . .*: . * *: : *:* *. ** . .*:* ::: ..: : : . . : :. : : : .. .::: : :* *: .* : :*. *** ", "identical_positions": 188, "similar_positions": 187, "identity": "26.9%" }, { "cls_id": "homologset.agr.MGI:1890110", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0ABK0LCL0-1", "uniprot_id": "A0ABK0LCL0_RAT", "id": "A0ABK0LCL0-1", "name": "", "aln": "--------------------------------------------------------------MTPLMFTLLLLFGFLCIRTDGSRLRQEDFPPRIVEHPSDVIVSKGEPTTLNCKAEGRPTPTIEWYKDGERVETDKDDPRSHRMLLPSGSLFFLRIVHGRRSKPDEGTYVCVARNYLGEAVSRNASLEVALLRDDFRQNPTDVVVAAGEPAILECQPPRGHPEPTIYWKK--------DKVRIDEKEERISIRGGKLMISNTRKSDAGMYTCVGTNMVGERDSDPAELTVFERPTFLRRPINQVVLEDEPAEFRCQVQGDPQPTVRWKKDD--ADLPRGRYDIKDD-YTLRIKKAISADEGTYVCIAENRVGKVEASATLTVR----APPQFVVRPRDQIVAQGRTVTFPCETKGNPQPAVFWQKEGSQNLLFPNQPQQPNSRCSVSPTG--DLTITNIQRSDAG-YYICQALTVAGSILAKAQLEVTDVLTDRPPPIILQGPINQTLAVDGTALLKCKATGEPLPVISWLKEGFTFLGRDP-RATIQDQGTLQIKNLR-ISDTGTYTCVATSSSGETSWSAVLDVTESG---ATISKNYDTNDLPGPPSKPQVTDVTKNSVTLSWQPG--TPGVL-PASAYIIEAFSQSVSNSWQTVANHVKTTLYTVRGLRPNTIYLFMVRAINPQGLSDPSPMSDPVRTQD--------ISPPAQGVDHRQVQKELG-DVTVRLHNPVVLTPTTVQVTWTVDRQP--QFIQGYRVMYRQTSG------------------------------------------------------------LQASTVWQNLDAKVPTERSAVLVNLKKGVTYEIKVRPYFNEFQGMDSESKTIRTTEEAPSAPPQSVTVLTVGSHNSTSISVSWDPP-PADHQNGIIQEYKIWCLGNE-----TRFHINKTVDATIRSVVIGGLFPGIQYRVEVAASTSAGVGVKSEPQPIIIGGRNE----VVITENNNSITEQITDVVKQPAFIAGIGGACWVILMGFSIWLYWRRKKRKGLSNYAVTFQRGDGGLMSNGSRPGLLNTGDPSYPWLADSWPATSLPVNNSNSGPNEIGNFGRGDFKHNVNKNLAEHGIKKEFLGMERNKNDVLPPVPGQGDKTATMLSDGAIYSSIDFTTKTTYNSSSQITQATPYATTQILHSNSIHELAVDLPDPQWKSSVQQKSDLMGFAYSLPDQNKGNNGGKGGKKKKTKNSSKAQKNNGSTWANVPLPPPPVQPLPGTELGHYPAEQ-ENGYDSD---SWCPPLPVQTYLHQGMEDELEEDEDRVPTPPVRG-VASSPAISFGQQSTATLTPSPREEMQPMLQAHLDELTR-----AYQFDIAKQTWHIQSNTPPPQPPVPPLGYASGALISDLETDVPDEDADDEEEPLEIPRPLRALDQTPGSSMDNLDSSVTGSMVNGWGSASDEDRNFSSHRSSVGSSSDGSIFASGSFAQALVAAADKAGFRLDGTSLTRTGKAFTSSQRQRPTSPFSTDSNTSAAQNQSQRPRPTKKHKGGRMDPQPVLPHRREGMPDDLPPPPDPPPGQGLRQQIGLSQHSGNVESSTERKGSSLERQQAANLEDTKSSLDCPAKTTVEWQHQTQDWINSTERQEETRKAPHKPGVGSEESLVPYSKPSFPSPGGHSSSGTASSKGSTGPRKAEILRGSHQRNANDLLDIGYVGSNSQGQFTE--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q7TPD3-1", "uniprot_id": "ROBO2_MOUSE", "id": "Q7TPD3-1", "name": "Roundabout homolog 2", "aln": "--------------------------------------------------------------MNPLMFTLLLLFGFLCIQIDGSRLRQEDFPPRIVEHPSDVIVSKGEPTTLNCKAEGRPTPTIEWYKDGERVETDKDDPRSHRMLLPSGSLFFLRIVHGRRSKPDEGSYVCVARNYLGEAVSRNASLEVALLRDDFRQNPTDVVVAAGEPAILECQPPRGHPEPTIYWKK--------DKVRIDDKEERISIRGGKLMISNTRKSDAGMYTCVGTNMVGERDSDPAELTVFERPTFLRRPINQVVLEEEAVEFRCQVQGDPQPTVRWKKDD--ADLPRGRYDIKDD-YTLRIKKAMSTDEGTYVCIAENRVGKVEASATLTVRVRPVAPPQFVVRPRDQIVAQGRTVTFPCETKGNPQPAVFWQKEGSQNLLFPNQPQQPNSRCSVSPTG--DLTITNIQRSDAG-YYICQALTVAGSILAKAQLEVTDVLTDRPPPIILQGPINQTLAVDGTALLKCKATGEPLPVISWLKEGFTFLGRDP-RATIQDQGTLQIKNLR-ISDTGTYTCVATSSSGETSWSAVLDVTESG---ATISKNYDMNDLPGPPSKPQVTDVSKNSVTLSWQPG--TPGVL-PASAYIIEAFSQSVSNSWQTVANHVKTTLYTVRGLRPNTIYLFMVRAINPQGLSDPSPMSDPVRTQD--------ISPPAQGVDHRQVQKELG-DVVVRLHNPVVLTPTTVQVTWTVDRQP--QFIQGYRVMYRQTSG------------------------------------------------------------LQASTVWQNLDAKVPTERSAVLVNLKKGVTYEIKVRPYFNEFQGMDSESKTVRTTEEAPSAPPQSVTVLTVGSHNSTSISVSWDPP-PADHQNGIIQEYKIWCLGNE-----TRFHINKTVDAAIRSVVIGGLFPGIQYRVEVAASTSAGVGVKSEPQPIIIGGRNE----VVITENNNSITEQITDVVKQPAFIAGIGGACWVILMGFSIWLYWRRKKRKGLSNYAVTFQRGDGGLMSNGSRPGLLNAGDPNYPWLADSWPATSLPVNNSNSGPNEIGNFGRG---------------------------DVLPPVPGQGDKTATMLSDGAIYSSIDFTTKTTYNSSSQITQATPYATTQILHSNSIHELAVDLPDPQWKSSVQQKTDLMGFGYSLPDQNKGNNGGKGGKKKKTKNSSKAQKNNGSTWANVPLPPPPVQPLPGTELGHYAAEQ-ENGYDSD---SWCPPLPVQTYLHQGMEDELEEDEDRVPTPPVRG-VASSPAISFGQQSTATLTPSPREEMQPMLQAHLDELTR-----AYQFDIAKQTWHIQSNTPPPQPPAPPLGYVSGALISDLETDVPDEDADDEEEPLEIPRPLRALDQTPGSSMDNLDSSVTG-------------------------------------------------------------KAFSSSQRQRPTSPFSTDSNTSAAQNQSQRPRPTKKHKGGRMDPQPVLPHRREGMPDDLPPPPDPPPGQGLRQQIGLSQHSGNVENSTERKGSSLERQQAANLEDTKSSLDCPAKTVLEWQRQTQDWINSTERQEETRKAPHKQGVGSEESLVPYSKPSFPSPGGHSSSGTSSSKGSTGPRKADVLRGSHQRNANDLLDIGYVGSNSQGQFTE--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9HCK4-1", "uniprot_id": "ROBO2_HUMAN", "id": "Q9HCK4-1", "name": "Roundabout homolog 2", "aln": "--------------------------------------------------------------MSLLMFTQLLLCGFLYVRVDGSRLRQEDFPPRIVEHPSDVIVSKGEPTTLNCKAEGRPTPTIEWYKDGERVETDKDDPRSHRMLLPSGSLFFLRIVHGRRSKPDEGSYVCVARNYLGEAVSRNASLEVALLRDDFRQNPTDVVVAAGEPAILECQPPRGHPEPTIYWKK--------DKVRIDDKEERISIRGGKLMISNTRKSDAGMYTCVGTNMVGERDSDPAELTVFERPTFLRRPINQVVLEEEAVEFRCQVQGDPQPTVRWKKDD--ADLPRGRYDIKDD-YTLRIKKTMSTDEGTYMCIAENRVGKMEASATLTVR----APPQFVVRPRDQIVAQGRTVTFPCETKGNPQPAVFWQKEGSQNLLFPNQPQQPNSRCSVSPTG--DLTITNIQRSDAG-YYICQALTVAGSILAKAQLEVTDVLTDRPPPIILQGPANQTLAVDGTALLKCKATGDPLPVISWLKEGFTFPGRDP-RATIQEQGTLQIKNLR-ISDTGTYTCVATSSSGETSWSAVLDVTESG---ATISKNYDLSDLPGPPSKPQVTDVTKNSVTLSWQPG--TPGTL-PASAYIIEAFSQSVSNSWQTVANHVKTTLYTVRGLRPNTIYLFMVRAINPQGLSDPSPMSDPVRTQD--------ISPPAQGVDHRQVQKELG-DVLVRLHNPVVLTPTTVQVTWTVDRQP--QFIQGYRVMYRQTSG------------------------------------------------------------LQATSSWQNLDAKVPTERSAVLVNLKKGVTYEIKVRPYFNEFQGMDSESKTVRTTEEAPSAPPQSVTVLTVGSYNSTSISVSWDPP-PPDHQNGIIQEYKIWCLGNE-----TRFHINKTVDAAIRSVIIGGLFPGIQYRVEVAASTSAGVGVKSEPQPIIIGRRNE----VVITENNNSITEQITDVVKQPAFIAGIGGACWVILMGFSIWLYWRRKKRKGLSNYAVTFQRGDGGLMSNGSRPGLLNAGDPSYPWLADSWPATSLPVNNSNSGPNEIGNFGRG---------------------------DVLPPVPGQGDKTATMLSDGAIYSSIDFTTKTSYNSSSQITQATPYATTQILHSNSIHELAVDLPDPQWKSSIQQKTDLMGFGYSLPDQNKGNNGGKGGKKKKNKNSSKPQKNNGSTWANVPLPPPPVQPLPGTELEHYAVEQQENGYDSD---SWCPPLPVQTYLHQGLEDELEEDDDRVPTPPVRG-VASSPAISFGQQSTATLTPSPREEMQPMLQAHLDELTR-----AYQFDIAKQTWHIQSNNQPPQPPVPPLGYVSGALISDLETDVADDDADDEEEALEIPRPLRALDQTPGSSMDNLDSSVTG-------------------------------------------------------------KAFTSSQRPRPTSPFSTDSNTSAALSQSQRPRPTKKHKGGRMDQQPALPHRREGMTD-------------------------------------------------------------------------------------------EEALVPYSKPSFPSPGGHSSSGTASSKGSTGPRKTEVLRAGHQRNASDLLDIGYMGSNSQGQFTGEL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "M9PC46-1", "uniprot_id": "M9PC46_DROME", "id": "M9PC46-1", "name": "", "aln": "MHLCEMRGMPLRLQPQCLTNESEIQIKIKSKIKNKTASEIKRRHRNNRDFHGERLKIMPVDRSRRAVFPLLLLLAGLNGLTQVGALKGE--NPRIIEHPMDTTVPKNDPFTFNCQAEGNPTPTIQWFKDGRELKTDTG---SHRIMLPAGGLFFLKVIHSRR-ESDAGTYWCEAKNEFGVARSRNATLQVAFLRDEFRLEPANTRVAQGEVALMECGAPRGSPEPQISWRKN------GQTLNLVGNKRIRIVDGGNLAIQEARQSDDGRYQCVVKNVVGTRESATAFLKVHVRPFLIRGPQNQTAVVGSSVVFQCRIGGDPLPDVLWRRTASGGNMPLRRVHVLED-RSLKLDDVTLEDMGEYTCEADNAVGGITATGILTVH----APPKFVIRPKNQLVEIGDEVLFECQANGHPRPTLYWSVEGNSSLLLPGYR-DGRMEVTLTPEGRSVLSIARFAREDSGKVVTCNALNAVGSVSSRTVVSVDTQF-ELPPPIIEQGPVNQTLPVKSIVVLPCRTLGTPVPQVSWYLDGIPIDVQEHERRNLSDAGALTISDLQRHEDEGLYTCVASNRNGKSSWSGYLRLDTPTNPNIKFFRAPELSTYPGPPGKPQMVEKGENSVTLSWTRSN-KVGGS-SLVGYVIEMFGKNETDGWVAVGTRVQNTTFTQTGLLPGVNYFFLIRAENSHGLSLPSPMSEPITVG---------TRYFNSGLDLSEARASLLSGDVVELSNASVVDSTSMKLTWQIING---KYVEGFYVYARQLPNPIVNNPAPVTSNTNPLLGSTSTSASASASASALISTKPNIAAAGKRDGETNQSGGGAPTPLNTKYRMLTILN-GGGASSCTITGLVQYTLYEFFIVPFYKSVEGKPSNSRIARTLEDVPSEAPYGMEALLLN---SSAVFLKWKAP-ELKDRHGVLLNYHVIVRGIDTAHNFSRILTNVTIDAASPTLVLANLTEGVMYTVGVAAGNNAGVGPYCVPATLRLDPITKRLD-PFINQRYPINQDHVNDVLTQPWFIILLGAILAVLMLSFGAMVFVKRK-HMMMKQSALNTMRGNHTS-DVLKMPSLSARNGNGYWLDSSTGGMVWRPSPGGDSLEMQKDHIADYAPV-------------------------CGAPGSPAGGGTSSGGSGGAGSGASGGDDIHGGHGSERNQQRYVGEYSNIPTDYAEVSSFGKAPSEYGRHGN-----ASPAPYATSSILSPHQQQQQQQPRYQQRPVPGYGLQRPMHPHYQQQQHQQQQAQQTHQQHQALQQHQQLPPSN---IYQQMSTTSEIYPTNTGPSRSVYSEQYYYPKDKQRHIHITENKLSNCH--TYEAAPGAKQSSPISSQFASVRRQQLPPNCSIGRESARFKVLNTDQGKNQ-QNLLDLDGSSMCYNGLADSGCGGSPSPMAMLMSHEDEHALYHTADGDLDDMERLYVK-----------------------------------------------------------VDEQQPPQQQQQLIPLVPQHPAEGHLQSWRNQSTRSSRKNGQECIKEPSELIYAPGSVAS------------------------------------------------------------------------------ERSLLSNSGSGTSSQPAGHNVXPLLPGSSLGQSQSKSQSQSQSQSDLQSQEQLYAREVRELLAWCERFNNGGVENFE--", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VPZ7-1", "uniprot_id": "Q9VPZ7_DROME", "id": "Q9VPZ7-1", "name": "", "aln": "-------------------------------------------------------------MDLRFVFIVFLLKW-------THAQGSH--PPRIVEHPIDTTVPRHEPATLNCKAEGSPTPTIQWYKDGVPLKILPG---SHRITLPAGGLFFLKVVNSRR-ETDAGIYWCEAKNELGVARSRNATLQVAVLRDEFRLEPQNTRIAQGDTALLECAAPRGIPEPTVTWKKG------GQKLDLEGSKRVRIVDGGNLAIQDARQTDEGQYQCIAKNPVGVRESSLATLKVHVKPYIIRGPHDQTVLEGASVTFPCRVGGDPMPDVLWLRTASGGNMPLDRVSVLED-RSLRLERVTIADEGEYSCEADNVVGAITAMGTLTVY----APPKFIQRPASKSVELGADTSFECRAIGNPKPTIFWTIKNNSTLIFPGAPPLDRFHSLNTEEGHSILTLTRFQRTDKDLVILCNAMNEVASITSRVQLSLDSQE-DRPPPIIISGPVNQTLPIKSLATLQCKAIGLPSPTISWYRDGIP--VQPSSKLNITTSGDLIISDLDRQQDQGLYTCVASSRAGKSTWSGFLRIELPTNPNIKFYRAPEQTKCPSAPGQPKILNATASALTIVWPTSD-KAGAS-SFLGYSVEMYCTNQSRTWIPIASRLSEPIFTVESLTQGAAYMFIVRAENSLGFSPPSPISEPITAGKLVGVRDGSESTGTSQLLLSDVETLLQANDVVELLEANASDSTTARLSWDIDSG---QYIEGFYLYARELHS--------------------------------------------------------------SEYKMVTLLNKGQGLSSCTVPGLAKASTYEFFLVPFYKSIVGKPSNSRRMRTLEDVPEAPPYGMEAIQFN---RTSVFLKWLPPQPNRTRNGILTSYNVVVKGLD-VHNTTRIFKNMTIDAAAPTLLLANLTTGVTYYIAVAAATRVGVGPFSKPAVLRIDARTQSLD-TGY-TRYPISRDIADDFLTQTWFIVLLGSIIAIIVFLLGALVLFKR--YQFIKQTSLGSLHGNHAIGTVRKFPTLPLNGGGAVGAGGSNSTAAAGQSGHGLWIDPTSG-VWRQAAG-------------------------GGNPGGVGSCTTKEQLPGYAQATAQQGQQPTLLPDYERLSPLNMPDYAEVACSTFKSPTHGAPPMGGGGGGQSASLYDSCGAYATTNVVANVKLYQN---RYATKPNQSSGSNNNNHQGNDYQSTGMYSAPPSAHYGCLEPKQQQQQQQP---NLMTTSTASTAILTNS--------------PAKVKKINITENKMDQLEGKSERTNPFNQQQQLLLASNALKQGLGAYANTTLAAQMASGGGAGTLRRQRQPKTLYKSENNILGKSGLRQNTMNASVG---------------APSNGQMDFLT-------------------------------------------------------------------GGPPSEGGDFSGLGLCNSTNQLLNDWASSASIAAPGDYHFGSKQPSKQHLYVKAKDG------------------------------------------------------------------------------TWSAVSSDAYQSFKHQQQH--HPFLAGSGDNTKSLASVNSLAGDSKFLS-------------------SFGSSANV---", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9W213-1", "uniprot_id": "Q9W213_DROME", "id": "Q9W213-1", "name": "", "aln": "-------------------------------------MHPMHPENHAIARSTSTTNNPSRSRSSRMWLLPAWLLLVLVASNGLPAVRGQYQSPRIIEHPTDLVVKKNEPATLNCKVEGKPEPTIEWFKDGEPVSTNEK--KSHRVQFKDGALFFYRTMQGKK-EQDGGEYWCVAKNRVGQAVSRHASLQIAVLRDDFRVEPKDTRVAKGETALLECGPPKGIPEPTLIWIKDGVPLDDLKAMSFGASSRVRIVDGGNLLISNVEPIDEGNYKCIAQNLVGTRESSYAKLIVQVKPYFMKEPKDQVMLYGQTATFHCSVGGDPPPKVLWKKEE--GNIPVSRARILHDEKSLEISNITPTDEGTYVCEAHNNVGQISARASLIVH----APPNFTKRPSNKKVGLNGVVQLPCMASGNPPPSVFWTKEGVSTLMFPNSS---HGRQHVAADG--TLQITDVRQEDEG-YYVCSAFSVVDSSTVRVFLQVSSLD-ERPPPIIQIGPANQTLPKGSVATLPCRATGNPSPRIKWFHDGHAVQAGNR--YSIIQGSSLRVDDLQ-LSDSGTYTCTASGERGETSWAATLTVEKPGS--TSLHRAADPSTYPAPPGTPKVLNVSRTSISLRWAKSQEKPGAVGPIIGYTVEYFSPDLQTGWIVAAQRVGDTQVTISGLTPGTSYVFLVRAENTQGISVPSGLSNTIKTIE--------ADFDAASANDLSAARTLLTGKSVELIDASAINASAVRLEWMLHVSADEKYVEGLRIHYKDASVP--------------------------------------------------------------SAQYHSITVMDASAESFVVGNLKKYTKYEFFLTPFFETIEGQPSNSKTALTYEDVPSAPPDNIQIGMYN---QTAGWVRWTPP-PSQHHNGNLYGYKIEVSAGN----TMKVLANMTLNATTTSVLLNNLTTGAVYSVRLNSFTKAGDGPYSKPISLFMDPTHHVHPPRAHPSGTHDGRHEGQDLTYHNNGNIPPGDINPTTHKKTTDYLSGPWLMVLVCIVLLVLVISAAISMVYFKRKHQMTKELGHLSVVSDNEITALNINSKESLWIDHHRGWRTADTDK--------------------------DSGLSESKLLSHVNSSQSNYNNSDGGTDYAEVDTRNLTTFYNCRKSPDNPTPYATTMIIGTSSSETCTKTTSISADKDSGTHSPYSDAFAGQVPAVPVVKSNYLQYPVEPINWSEFLPPPPEHPPPSSTYGYAQGSPESSRKSSKSAGSGISTNQSILNASIHSSSSGGFSAWGVSPQYAVACPPENVYSNPLSAVAGGTQNRYQITPTNQHPPQLPAYFATTGP-----GGAVPPNHLPFATQRHAASEYQAGLNAARCAQSRACNSCDALATPSPMQPPPPVPVPEGWYQPVHPNSHPMHPTSSN-----------------------------------------------------------------HQIYQCSSECSDHSRSSQSHKRQLQLEEHGSSAKQRGGHHRRRAPVVQPCMESENEN--------------------------------------------------------------------------------------------MLAEYEQRQYTSDCCNSSREGDTCSCSEGSCLYAEAGEPAPRQMTAKNT----------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : * . ***:*** * * : :* *:**:.** * ***:*:*** :. ***: : *.*** : ::.:: : * * * * *:* .* * **:*:*::*.***:** :* :. :* *: *::** .*:* *** : * * . : : ... : **:* *.:.. * * * *: * ** *:* * * * :* ::: * :*. : .. * * : *** * * * : .::* * : .* :*.:. * * * * *.* ** : * . * * ***:* ** .: * . . : * : *:* *:::* :. ..*::*. . . : * * :: . : * . *.*:. . * :. :.: : ***** ** ****. . . * *:: * * * :.* :* . .: . * :.:* .* * ***.*:. *:::*:. * : . .: : : . *..*. *:: : .:::: * . . * . .* :* : . * . :: . * .* .. *.*::** *. *:* ** :*:.: . .. * . *.* :. . .:: :: * : ::::* : :: .: * .: .* : **: : *::: . * *:*: * *:.*. .* .: . :: : * .* ::* : *:: . : :. * *::*: :::: .* * * : : : . .* * . * : :. . . *. : * : : . : . . . . : . : . .: . :: . : : : : .. .. . . . * : : : . . . . . :. . . . : * : . . : . . ", "identical_positions": 206, "similar_positions": 303, "identity": "11.87%" }, { "cls_id": "homologset.agr.MGI:1890127", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D4A7M0-1", "uniprot_id": "D4A7M0_RAT", "id": "D4A7M0-1", "name": "Plexin-C1", "aln": "MEVSRRKAPPRPPYPAAPLPLIAYLLALAVPARGADEPVWRSEQAIGAIAASRADGVFVASGSCLDQLDYSLKNRLSRLYRDQAGNCTEPVSLAPPARPRPGSSFSKLLLPYREGATGLEGLLLTGWTFDRGACEVRPLGNLNRSSLRNGTEVVSCHPQGSTAGVVYRASGTDLWYLAVAATYVLPEPETANRCNPAASDRDTAIALKNTEGRSLATQELGRLKLRGSAGSLHFVDAFLWNGSVYFPYYP-YNYTSGAATGWPSMARIAQSTEVLFQGQAALDCGHGHPEGRRLLLSSSLV--EAVDIWAGVFSAATGEGQEKRSPATTALCLFRMSEIQARARSCSWDFQATEHNCKEGDQPEQVQPIASSTLIHSDLTSVYGTVVMNRIVLFLGTGDGQLLKVVLGENLTSNCPEVIYEIKEETPVFYKLVPHPVKDTYIYLTAGKEVRRIQVANCSKRKSCFQCLAAADPHCGWCLPLQRSSFMGGGDAVRHFLNWRSMAEGPHHTPKSQWSKALKERTTVTIVGSVSARHS-----ECVVKNADTGKLLCQGRSQMNRTCACNIPSRPSN-NVFVVNATFTFPSWSVSERFNFTNCASVR---------ECPACIETGCAWCKRDKRCIHPFTPCEPSDYERNQELCHVAVEKPPKDSGGGRVKESKRNRTDPALQVFYIKAIEPQKISTLGKSNVIVTGANFTQASNITMILRGTSTCEKDVIRVSHVLNDTHMKFSLPSSRKEMKDVCIQFDGGNCSSAGALSYIALPHCSLIVPATTWISGGQNITIMGRNFDVIDNLIISHELKGNINVSINVSEYCMATSCRFLAPNLKSSKGRTNVVVKLRVQDTYLDCGTLQYLEDPRFTGYRVESEIDTELEVKIQKENDNFNISRDDIDITLFHGENKQFNCSFENITRNQDLTTILCKIKSIKNANTIATSSKKVRVKLGNLELYVEQESVPSTWYFLIALPILLAIVIVVAVVVTRHKSKELSRKQSQQLELLESELRKEIRDGFAELQMDKLDVVDSFGTVPFLDYKHFALRTFFPESGGFTHIFTEDMHN-RDANDKNESLTALDALICNKSFLVTVIHTLEKQKNFSVKDRCLFASFLTIALQTKLVYLTSILEVLTRDLMEQCSNMQPKLMLRRTESVVEKLLTNWMSVCLSGFLRETVGEPFYLLVTTLNQKINKGPVDVITCKALYTLNEDWLLWQVPEFNTVALNVVFEKIPENESADVCRNISVNVLDCDTIGQAKEKIFQAFLSKNGSPYGLQLNEIGLELQVGTRQKELLDIDSSSVILEDGITKLNTIGHYEISNGSTIKVFK--------KIANFTSDVEYSDDHCHLILPDSEAFQVVQGKRHRGKHKFKVKEMYLTKLLSTKVAIHSVLEKLFRSIWSLPNSRAPFAIKYFFDFLDAQAENKKITDPDVVHIWKTNSLPLRFWVNILKNPQFVF-DIKKTPHIDSCLSVIAQAFMDAFSLTEQQLGKEAPTNKLLYAKDIPTYKEEVKSYYKAIRDLPPLSSLEMEEFLTQESKKHENEFNEEVALTEIYKYIVKYFDEILNKLERERGLEEAQKQLLHVKVLFDEKKKCKWM", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9QZC2-1", "uniprot_id": "PLXC1_MOUSE", "id": "Q9QZC2-1", "name": "Plexin-C1", "aln": "MEVSRRKTPPRPPYPAAPLPLIAYLLALAAPARGADEPVWRSEQAIGAIAASRADGVFVASGSCLDQLDYSLKNRLSRLYRDQAGNCTEPVSLAPPARPRPGSSFSKLLLPYREGATGLEGLLLTGWTFDRGACEVRPLGNLNRSSLRNGTEVVSCHPQGSTAGVVYRASGTDLWYLAVAATYVLPEPETANRCNPAASDRDTAIALKNTEGRSLATQELGRLKLRGSAGSLHFVDAFLWNGSVYFPYYP-YNYTSGAATGWPSMARIAQSTEVLFQGQAALDCDHGHPEGRRLLLSSSLV--EAVDIWAGVFSAATGEGQERRSPATTALCLFRMSEIQAHARSCSWDFQATEHNCKEGDRPERVQPIASSTLIHSDLTSVYGTVVMNRTVLFLGTGDGQLLKVVLGENLTSNCPEVIYEIKEETPVFYKLVPHPMKNIYIYLTAGKEVRRIPVANCSKRKSCSECLAAADPHCGWCLPLQRCTFQGDCTHAGSFENWLDISSGPKKCPKIQILRSLRERTTVTIVGSISARHS-----ECVVKNADTGKLLCQGRSQLNWTCACNIPSRPSY-NVLVVNATFSFPSWNLSERFNFTNCASLK---------ECPACIRSGCAWCKRDKKCIHPFTPCEPSDYERNQELCQVAVEKSPKDSGGGRVKESKRNRTDGAVQVFYIKAIEPQKISTLGKSNVIVTGANFTQASNITMILRGTSTCERDVIRVSHVLNDTHMKFSLPSSRKEMKDVCIQFDGGTCSSAGALSYIALPHCSLIVPATTWISGGQNITIMGRNFDVIDNLIISHELKGNANVNINVSEYCAATFCRFLAPNLKSSKVRTNVAVKLRVQDTYLDCGTLQYLEDPRFTGYRVESEIDTELEVKIQKENDNFNISKDDIDITLFHGENKQFNCSFENITRNQDLTTILCKIKSIKNANTIASSSKKVRVKLGNLELYVEQESVPSTWYFLIALPILLAIVIVVAVVVTRYKSKELSRKQSQQLELLESELRKEIRDGFAELQMDKLDVVDSFGTVPFLDYKHFALRTFFPESGGFTHIFTEDMHN-RDANDKNESLTALDALICNKSFLVTVIHTLEKQKNFSVKDRCLFASFLTIALQTKLVYLTSILEVLTRDLMEQCSNMQPKLMLRRTESVVEKLLTNWMSVCLSGFLRETVGEPFYLLVTTLNQKINKGPVDVITCKALYTLNEDWLLWQVPEFNTVALNVVFEKIPENESADVCRNISVNVLDCDTIGQAKEKVFQAFLSKNGSPYGLQLNEIGLELQVGTRQKELLDIDSSSVILEDGITKLNTIGHYEISNGSTIKVFK--------KIANFTSDVEYSDDHCHLILPDSEAFQVVQGKRHRGKHKFKVKEMYLTKLLSTKVAIHSVLEKLFRSIWSLPNSRAPFAIKYFFDFLDAQAENKKITDPDVVHIWKTNSLPLRFWVNILKNPQFVF-DIKKTPHIDSCLSVIAQAFMDAFSLTEQQLGKEAPTNKLLYAKDIPTYKEEVKSYYKAIRDLPPLSSLEMEEFLTQESKKHENEFNEEVALTEIYKYIVKYFDEILNKLERERGLEEAQKQLLHVKVLFDEKKKCKWM", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O60486-1", "uniprot_id": "PLXC1_HUMAN", "id": "O60486-1", "name": "Plexin-C1", "aln": "MEVSRRKAPPRPPRPAAPLPLLAYLLALAAPGRGADEPVWRSEQAIGAIAASQEDGVFVASGSCLDQLDYSLEHSLSRLYRDQAGNCTEPVSLAPPARPRPGSSFSKLLLPYREGAAGLGGLLLTGWTFDRGACEVRPLGNLSRNSLRNGTEVVSCHPQGSTAGVVYRAGRNNRWYLAVAATYVLPEPETASRCNPAASDHDTAIALKDTEGRSLATQELGRLKLCEGAGSLHFVDAFLWNGSIYFPYYP-YNYTSGAATGWPSMARIAQSTEVLFQGQASLDCGHGHPDGRRLLLSSSLV--EALDVWAGVFSAAAGEGQERRSPTTTALCLFRMSEIQARAKRVSWDFKTAESHCKEGDQPERVQPIASSTLIHSDLTSVYGTVVMNRTVLFLGTGDGQLLKVILGENLTSNCPEVIYEIKEETPVFYKLVPDPVKNIYIYLTAGKEVRRIRVANCNKHKSCSECLTATDPHCGWCHSLQRCTFQGDCVHSENLENWLDISSGAKKCPKIQIIRSSKEKTTVTMVGSFSPRHS-----KCMVKNVDSSRELCQNKSQPNRTCTCSIPTRATYKDVSVVNVMFSFGSWNLSDRFNFTNCSSLK---------ECPACVETGCAWCKSARRCIHPFTACDPSDYERNQEQCPVAVEKT---SGGGRPKENKGNRTNQALQVFYIKSIEPQKVSTLGKSNVIVTGANFTRASNITMILKGTSTCDKDVIQVSHVLNDTHMKFSLPSSRKEMKDVCIQFDGGNCSSVGSLSYIALPHCSLIFPATTWISGGQNITMMGRNFDVIDNLIISHELKG----NINVSEYCVATYCGFLAPSLKSSKVRTNVTVKLRVQDTYLDCGTLQYREDPRFTGYRVESEVDTELEVKIQKENDNFNISKKDIEITLFHGENGQLNCSFENITRNQDLTTILCKIKGIKTASTIANSSKKVRVKLGNLELYVEQESVPSTWYFLIVLPVLLVIVIFAAVGVTRHKSKELSRKQSQQLELLESELRKEIRDGFAELQMDKLDVVDSFGTVPFLDYKHFALRTFFPESGGFTHIFTEDMHN-RDANDKNESLTALDALICNKSFLVTVIHTLEKQKNFSVKDRCLFASFLTIALQTKLVYLTSILEVLTRDLMEQCSNMQPKLMLRRTESVVEKLLTNWMSVCLSGFLRETVGEPFYLLVTTLNQKINKGPVDVITCKALYTLNEDWLLWQVPEFSTVALNVVFEKIPENESADVCRNISVNVLDCDTIGQAKEKIFQAFLSKNGSPYGLQLNEIGLELQMGTRQKELLDIDSSSVILEDGITKLNTIGHYEISNGSTIKVFK--------KIANFTSDVEYSDDHCHLILPDSEAFQDVQGKRHRGKHKFKVKEMYLTKLLSTKVAIHSVLEKLFRSIWSLPNSRAPFAIKYFFDFLDAQAENKKITDPDVVHIWKTNSLPLRFWVNILKNPQFVF-DIKKTPHIDGCLSVIAQAFMDAFSLTEQQLGKEAPTNKLLYAKDIPTYKEEVKSYYKAIRDLPPLSSSEMEEFLTQESKKHENEFNEEVALTEIYKYIVKYFDEILNKLERERGLEEAQKQLLHVKVLFDEKKKCKWM", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M3ARP5-1", "uniprot_id": "A0A8M3ARP5_DANRE", "id": "A0A8M3ARP5-1", "name": "", "aln": "----------MRGYLLGVIVFLKYCICDDVVDFGEDIKDFVVG----------TSKLFVLTENRLYQMRHDLSEEKK---KKDINNSTHPINILVPFDN--------------------NGTLITCGTYEHGYCEVLDINDITNSIYFESKLFMG--PKETEKSIAFIASTSSSRYLLVGKKLDQSTSQSPVVTLRNTVQTQFGGIFSYSE-------EGSDPAIQTTARDVEFVDGFQRASSLDLYLFLNTKTDSEWKVHVLRMDGSKSKKSEIFRSLKSAVIKCCSDKARPVLVSSAVIPSEKTVIWAGVFSAQD-----QQDPENTALALYDISRIQGRVKEFCTQGEKTCS-------SESDLQPLSVVFKSSSMSSVAAVRNGSWIVLFMGNSDGQLIKLVLDENYTPSCPTVLYKSDDERAVFPRMHFDPVDSKYIYIALRKQIRRVSVVRCAKYNTLKDCRSALDPLCGWCVNTQRCSTHDECSNSS----WVSIPKDSLQTELLSFQVAQKPSTQITLHLALSLESTGNPAFSCVFSSGSVNLCNGSDLTAVFPNCSCTFSNQLPN---TGVSATVTVEDQKITKMLILTNCSSITDNSPNVSYTQCVQCISSGCHWSSSSKRCGWTQGREPQLNIQDACKDLLSEYKEP------------------------EILSLEPHKVSFNGRNNVLLRGRNLDSVT--KIRIQGDLGCIAKESPVFDPSSDTLVFNIPPSESKGTVKMCVVTPDNRCHGNSIITYSSQPRCTGVQPRNSWRSGGRKIHVQGTNMEYVESVIVQ-------PSNIFLKSQYDASSRDMWFYSHRIEGSDHFTLSLMVGNSTEACDHDFSYEPDPVFTGFTTLQVAN-DLQVNIQKKADKLNLNISEVKVAGLHGDKG-YQCVVERIESN----AVICKIK----AGPGALDSLNISIGHFYVKQTFESPSGMKYFSILVVLIVIIILGAVVGVIVHRKSQKQMSKKMNDQLELMESNIRRDIRQGFVDLQTEKSDLIDNVGAIPFLDYKHFASRIFFPEAGTLTAVMIRDIGEDSEQTTVDEKCLAFAELIRDKQFLSCFVHALEEQKNFSIKDKCTVASLLTLALHGDLLYLTEIMEDLLQSLMDQSSNANPKLLLRRTESIVEKLLTNWMSICLYGFLRESVGQPLFLLVSALTQQISKGPVDSVTEKALYTLSEDWLLCQAQDFEPLKLKVVFAVG---TGEEISESLEVIALTCDTIQQVKEKILQTFQRKFGFRYTQQIRDIEIEYEKEGKFVMLQEVDDTSEIRGH-VTMLNTLKHYQVGDGACIKVITPKIHAPLKTQNSVKDDKNFSIKYFHLVDPDIDTDLSN----HPEKKALKIKEMYLIKLLSTKVAVHSFVENLFKSIWGLPNNKAPLAVKYFFDFLDEQAERKKITDPDVLHIWKTNSLPLRFWVNILKNPDFVFSDMEKSPHLDGCLSVIAQAFMDSFSLTDTHLDKHSPTNKLLYGKDIPQYKQEVKSYYKLVKDQTSISSQELKTFLQEESKKHQNEFNESAALRELYKYMQRYFTEIFQKLEQTDAPSNLKENMHRVKELFDNMKRSGWN", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . : :: * :. . * * : . :** : . * *: :.*.. . :.: .*.*.*:.: * * *:* *:::* *** :.::... :.. .:. *: : .:.: *. .. ** *. . . .::. : : : . :. :* * . : * .:.***.* .*: : : : * . * .... :*:. : ..* :*:**::: * :******* ::.* .***.*: :*.**.:.: . : : : .* * .: *.::** .. . ***:*..****:*::*.** *..** *:*: .:* .** :: .*:.. ***:: *::**: *..* * :: :* :* ** **** **.: . * .:.... : . : : * :*: :.* . : .*:... . . .. : .*:*.:..: . *.. .:. . .::. : :***:*: :* *: :** *.. ::* . : : : ::. * ::**:*:* *:.**:: * *: .: .: ::* * . * . .** : **. * .:*: .. * . . ::* : *:*: : * .:* ***::* : * *:: ::.:*:. .* :.. *: : . : . . : :.* :.* ** ***: . . : :*:*:***: *::*:. .::.:: :**:: :* .*.* * :::**** *.. * .* :: : :: .*. * . : :*:.* ::: : ...* * * ..*::*:* .:****:**::*::**:**.:** :* *::*..*::********* * ****:* :* :: .*: : : . :*. *: ** :*.** .:*:**:*****:**:* .**:**:**: .*:***.*:* * :.**:*.** :***:******:**********:** *****:**:*::***::*.*:*.***** :* ******.***** *. :*..: *:*** . ::...:.* .* **** *.***::*:* * * * *:.:* :* : : * ::*.:* * . :* ***: **::.:*: ***:. . ....* ::* .: **: ** :: * *: :*:***** ********:**.:*:**:***.***.:**:*:******** ***.********:********************:*** *::*:**:*.***********:****: :*.*.:*******.**** **:******* ::* ..:** *:: ** :*****:*****..** *:***: :** **::***: . .: :::: :** ***: *:. * ", "identical_positions": 506, "similar_positions": 503, "identity": "31.59%" }, { "cls_id": "homologset.agr.MGI:1890149", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P06753-1", "uniprot_id": "TPM3_HUMAN", "id": "P06753-1", "name": "Tropomyosin alpha-3 chain", "aln": "MMEAIKKKMQMLKLDKENALDRAEQAEAEQKQAEERSKQLEDELAAMQKKLKGTEDELDKYSEALKDAQEKLELAEKKAADAEAEVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIENRALKDEEKMELQEIQLKEAKHIAEEADRKYEEVARKLVIIEGDLERTEERAELAESKCSELEEELKNVTNNLKSLEAQAEKYSQKEDKYEEEIKILTDKLKEAETRAEFAERSVAKLEKTIDDLEDELYAQKLKYKAISEELDHALNDMTSI", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P21107-1", "uniprot_id": "TPM3_MOUSE", "id": "P21107-1", "name": "Tropomyosin alpha-3 chain", "aln": "MMEAIKKKMQMLKLDKENVLDRAEQAEAEQKQAEERSKQLEDELATMQKKLKGTEDELDKYSEALKDAQEKLELAEKKAADAEAEVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIENRALKDEEKMELQEIQLKEAKHIAEEADRKYEEVARKLVIIEGDLERTEERAELAESKCSELEEELKNVTNNLKSLEAQAEKYSQKEDKYEEEIKILTDKLKEAETRAEFAERSVAKLEKTIDDLEDELYAQKLKYKAISDELDHALNDMTSI", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A2R8Q650-1", "uniprot_id": "A0A2R8Q650_DANRE", "id": "A0A2R8Q650-1", "name": "", "aln": "-MEAVKKKMMMLKLDKENALDQAEQAETDRKAAEERSKQHEDELIQMQKKLKGTEDELDKYSEALKDAQEKLEISEKKAADAEAEVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIENRALKDEEKMELQEIQLKEAKHIAEEADRKYEEVARKLVIVEGELERTEERAELAESHVKQMEEELRALDQTLKTLQASEEKYSQKEDKYEEEIKILTDKLKEAETRAEFAERSVAKLEKTIDDLEEKLRDAKEENIKIHATLDQTLSELNSF", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P09491-1", "uniprot_id": "TPM2_DROME", "id": "P09491-1", "name": "Tropomyosin-2", "aln": "-MDAIKKKMQAMKLEKDNAIDKADTCENQAKDANSRADKLNEEVRDLEKKFVQVEIDLVTAKEQLEKANTELEEKEKLLTATESEVATQNRKVQQIEEDLEKSEERSTTAQQKLLEATQSADENNRMCKVLENRSQQDEERMDQLTNQLKEARMLAEDADTKSDEVSRKLAFVEDELEVAEDRVRSGESKIMELEEELKVVGNSLKSLEVSEEKANQRVEEFKREMKTLSIKLKEAEQRAEHAEKQVKRLQKEVDRLEDRLFNEKEKYKAICDDLDQTFAELTGY", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P17536-1", "uniprot_id": "TPM1_YEAST", "id": "P17536-1", "name": "Tropomyosin-1", "aln": "-MDKIREKLSNLKLEAESWQEKYEELKEKNKDLEQENVEKENQIKSLTVKNQQLEDEIEKLEAGLSDSKQ----TEQDNVEKENQIKSLTVKNHQLEEEIEKLEAELAESKQLSEDSHHLQSNNDN----FSKKNQQLEEDLEESDTKLKETTEKLRESDLKADQLERRVAALEEQREEWERKNEELTVKYEDAKKELDEIAASLENL-----------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *: :::*: :**: :. :: : : . * :.. : :::: : * * :: . . *..:: *: . * :: : . : : :**:::: : . : : * :: : .:.:. :.:: : ** :: :***: .::* * ::: *::. :* : * * : . : : ::** : .*:.* ", "identical_positions": 28, "similar_positions": 86, "identity": "9.82%" }, { "cls_id": "homologset.agr.MGI:1890156", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9Z2Q7-1", "uniprot_id": "STX8_RAT", "id": "Q9Z2Q7-1", "name": "Syntaxin-8", "aln": "---MAPDPWFSTYDSTCQIAQEIAEKIQERNQCERRGEKTPKLTLTIRTLLKNLKVKIDLLKDLLLRAVSTRQITQLEGDRRQNLLDDLVTRERLLLASFKNEGSEPDLIRSSLMSEEAKRGTPNPWLCEEPEETRGLGFDEIRQQQQKIIQEQDAGLDALSSIISRQKQMGQEIGNELDEQNEIIDDLANLVENTDEKLRTEARRVTLVDRKSASCGMIMVILLLLVAIVVVAVWPTN", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O88983-1", "uniprot_id": "STX8_MOUSE", "id": "O88983-1", "name": "Syntaxin-8", "aln": "---MAPDPWFSTYDSTCQIAQEIAEKIQERNQCERRGEKTPKLTLTIRTLLKNLKVKIDLLKDLLLRAVSTRQITQLEGDRRQNLLDDLVTRERLLLASFKNEGAEPDLIRSSLMSEEAKRGTPNPWLCEEPEETRGLGFDEIRQQQQKIIQEQDAGLDALSSIISRQKQMGQEIGNELDEQNEIIDDLANLVENTDEKLRTEARRVTLVDRKSTSCGMIMVILLLLVAIVVVAVWPTN", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9UNK0-1", "uniprot_id": "STX8_HUMAN", "id": "Q9UNK0-1", "name": "Syntaxin-8", "aln": "---MAPDPWFSTYDSTCQIAQEIAEKIQQRNQYERKGEKAPKLTVTIRALLQNLKEKIALLKDLLLRAVSTHQITQLEGDRRQNLLDDLVTRERLLLASFKNEGAEPDLIRSSLMSEEAKRGAPNPWLFEEPEETRGLGFDEIRQQQQKIIQEQDAGLDALSSIISRQKQMGQEIGNELDEQNEIIDDLANLVENTDEKLRNETRRVNMVDRKSASCGMIMVILLLLVAIVVVAVWPTN", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VV76-1", "uniprot_id": "Q9VV76_DROME", "id": "Q9VV76-1", "name": "", "aln": "MALVDHDSWDIEYEGCERLRHQLLVYLNQRQQLNPRTSQFVQLTSSIQTGIEQLAKDMKHLKVVLDNAITWETSPEEELQQRRIDWDRLTSQLREIREKFANSSRSNVPAASGSAWQDQDLGPG----HSNSSRNTALDVEALKQKKTEMLAQQNEGLEVLSATLSRQRQLATQLGNEVEDQNNILDNLANAMDRVETGVQRETQSIGQVNRRDSTWGYWLVIIALFVAIIVVVFV---", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : *.* *:. :: ::: :::*:* : : .: :** :*:: :::* .: ** :* .*:: . .: * ::*: * *.:: * : .* *.. . *. :: . *. .:.... .*..: ::*:: ::: :*: **:.**: :***:*:. ::***:::**:*:*:*** ::..: :: *:: : *:*:.:: * :**: *:***:**.. ", "identical_positions": 55, "similar_positions": 104, "identity": "23.01%" }, { "cls_id": "homologset.agr.MGI:1890165", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q6ZQ58-1", "uniprot_id": "LARP1_MOUSE", "id": "Q6ZQ58-1", "name": "La-related protein 1", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------MATQVEPLLPAGAPLLQAEEHG-LARKKP--APDAQAESGPGDG-GGEPDGGVRRPRPACARPGRDGA---ERESPRPP--AAAEAPAGSDGEDGG----------------RRDFVEAPPPKVNPWTKHAPPP---------------------------------------------------------------------AAVNGQPPPEPSAPAKVVRAAAP----------------------------KPRKGSKVGDFGDAVNWPTPG------------------EIAHKSVQPQSHKPQPARKLPPKKDMKEQEKGDGSDSKESPKTKSDESGEEKN------------GDEDCQRGGQ------------------KKKGSKHKWVPLQIDMKPEVPREKLASRPTRPQEPRHTPAVRG---------------------EMKGSEPATYMPVSVAPPTPAWQPETKVEPAWHDQDETSSVKSDGAGGARASFRGRGRGRGRGRGRGRGGTRTHFDYQ-------------------FGYRKFDGTEGPRTHKYMNNITYYFDNVSSNEIYSMDQELLKDYIKRQIEYYFSVDNLERDFFLRRKMDADGFLPITLIASFHRVQALTT--DISLIFAALKDSKVVEMVE-EKVRRREEPEKWPLPGPPIVDYSQTDFSQLLN---------------------CPEFVPRQHYQKETESAPGSPRAVTP---------------------------------------------------------VPTKTEEVSNLKTLPKGLSASLPDLDSESWIEVKKRPRPSPARP--------------------------------------------------------------------------------KKPEEPRFSHPTALPQQLPSQQLMSKDQDEQEELDFLFDEEMEQMD----GRKNTFTAWS--EEDSDYEIDDRDVNKILIVTQTPPYMRRHPGGDRTGNHTSRAKMSAELAKVINDGLFYYEQDLWTEKFEPEYSQIKQEVENFKKVNMISREQFDTLTP--EPPVDPNQEVPPGPPR------FQQVPTDALANKLFGAPEPSTIARSLPTTVPESPNYRNARTPRTPRTPQLKDSSQTPRFYPVVKEGRTLDAKMPRKRKTRHSSNPPLESHVGWVMDSREHRPRTASISS--SPSEGTPAVGSYG-CTPQSLPKFQHPSHELLKENGFTQHVYHKYRRRCLNERKRLGIGQSQEMNTLFRFWSFFLRDHFNKKMYEEFKQLALEDAKEGYRYGLECLFRYYSYGLEKKFRLDIFKDFQEETVKDYEAGQLYGLEKFWAFLKYSKAKN-LDIDPKLQEYLGKFRRLEDFRVDPPMGEEGNH---------------------------------------------------------------------------------------------------------------KRHPVVAGGSG-EGRKRCPSQSSSRPATGISQPPTTPTGQATREDAKWTSQHSDTLTLRK--------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8I6GJC3-1", "uniprot_id": "A0A8I6GJC3_RAT", "id": "A0A8I6GJC3-1", "name": "", "aln": "-----------------MAAGRRGLGGTFRPARARPPPRRPRPSRAASRGARPPAARRGSRGLARLSAPLPPGPSAPLQPPEPPRAGGGGTQAADRGPPGRLGAPELSARRAAQRPPVRAAPGPRGPGPGAPPAASSGARGAPGPSAQMATQVEPLLPAGAALLQADEHG-LARKKP--APDTQAESGPGDG-GGEPDGGVRRPRPACARPGRDGT---ERESPRPP--AAAEAPAGSDGEDGG----------------RRDFVEAPPPKVNPWTKHAPPPP--------------------------------------------------------------------SAVNGQPPPEPSAPAKVVRAAAP----------------------------KQRKGSKVGDFGDAINWPTPG------------------EIAHKSVQPQSHKPQPARKLPPKKDMKEQEKGDGSDSKESPKTKSDESGEEKN------------GDEDCQRGGQ------------------KKKGNKHKWVPLQIDMKPEVPREKLASRPTRPQEPRHTPAIRG---------------------EIKGSEPATYMPVSVAPPTPAWQPETKPEPAWHDQDETSSVKSDGAGGARASFRGRGRGRGRGRGRGRGGTRTHFDYQ-------------------FGYRKFDGTEGSRTPKYMNNITYYFDNVSSTEIYSVDQELLKDYIKRQIEYYFSVDNLERDFFLRRKMDADGFLPITLIASFHRVQALTT--DISLIFAALKDSKVVEMVE-EKVRRREEPEKWPLPGPPIVDYSQTDFSQLLN---------------------CPEFVPRQHYQKETESAPGSPRAVTP---------------------------------------------------------VPTKTEEVSNLKTLPKGLSASLPDLDSESWIEVKKRPRPSPARP--------------------------------------------------------------------------------KKSEEPRFSHPTALPQQIPSQQLMSKDQDEQEELDFLFDEEMEQMD----GRKNTFTAWS--DEDSDYEIDDRDVNKILIVTQTPPYMRRHPGGDRTGNHTSRAKMSAELAKVINDGLFYYEQDLWTEKFEPEYSQIKQEVENFKKVNMISREQFDTLTP--EPPVDPNQEVPPGPPR------YQQVPTDALANKLFGAPEPSTIARSLPTTVPESPNYRNARTPRTPRTPQLKDSSQTSRFYPVVKEGRTLDAKMPRKRKTRHSSNPPLESHVGWVMDSREHRPRTASISS--SPSEGTPAVGSYG-CTPQSLPKFQHPSHELLKENGFTQHVYHKYRRRCLNERKRLGIGQSQEMNTLFRFWSFFLRDHFNKKMYEEFKQLALEDAKEGYRYGLECLFRYYSYGLEKKFRLDIFKDFQEETVKDYEAGQLYGLEKFWAFLKYSKAKN-LDIDPKLQEYLGKFRRLEDFRVDPPMGEEGNH---------------------------------------------------------------------------------------------------------------KRHPVVAGGSG-EGRKRCPSQSSSRPATGISQPPTTPTGQATREDAKWTSQHTDTLTLGK--------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q6PKG0-1", "uniprot_id": "LARP1_HUMAN", "id": "Q6PKG0-1", "name": "La-related protein 1", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------MATQVEPLLPGGATLLQAEEHGGLVRKKPPPAPEGKGEPGPNDVRGGEPDGSARRPRPPCAKPHKEGTGQQERESPRPLQLPGAEGPAISDGEEGGGEPGAGGGAAGAAGAGRRDFVEAPPPKVNPWTKNALPPV-------------------------------------------------------------------LTTVNGQSPPEHSAPAKVVRAAVP----------------------------KQRKGSKVGDFGDAINWPTPG------------------EIAHKSVQPQSHKPQPTRKLPPKKDMKEQEKGEGSDSKESPKTKSDESGEEKN------------GDEDCQRGGQ------------------KKKGNKHKWVPLQIDMKPEVPREKLASRPTRPPEPRHIPANRG---------------------EIKGSESATYVP--VAPPTPAWQPEIKPEPAWHDQDETSSVKSDGAGGARASFRGRGRGRGRGRGRGRGGTRTHFDYQ-------------------FGYRKFDGVEGPRTPKYMNNITYYFDNVSSTELYSVDQELLKDYIKRQIEYYFSVDNLERDFFLRRKMDADGFLPITLIASFHRVQALTT--DISLIFAALKDSKVVEIVD-EKVRRREEPEKWPLP--PIVDYSQTDFSQLLN---------------------CPEFVPRQHYQKETESAPGSPRAVTP---------------------------------------------------------VPTKTEEVSNLKTLPKGLSASLPDLDSENWIEVKKRPRPSPARP--------------------------------------------------------------------------------KKSEESRFSHLTSLPQQLPSQQLMSKDQDEQEELDFLFDEEMEQMD----GRKNTFTAWS--DEESDYEIDDRDVNKILIVTQTPHYMRRHPGGDRTGNHTSRAKMSAELAKVINDGLFYYEQDLWAEKFEPEYSQIKQEVENFKKVNMISREQFDTLTP--EPPVDPNQEVPPGPPR------FQQVPTDALANKLFGAPEPSTIARSLPTTVPESPNYRNTRTPRTPRTPQLKDSSQTSRFYPVVKEGRTLDAKMPRKRKTRHSSNPPLESHVGWVMDSREHRPRTASISS--SPSEGTPTVGSYG-CTPQSLPKFQHPSHELLKENGFTQHVYHKYRRRCLNERKRLGIGQSQEMNTLFRFWSFFLRDHFNKKMYEEFKQLALEDAKEGYRYGLECLFRYYSYGLEKKFRLDIFKDFQEETVKDYEAGQLYGLEKFWAFLKYSKAKN-LDIDPKLQEYLGKFRRLEDFRVDPPMGEEGNH---------------------------------------------------------------------------------------------------------------KRHSVVAGGGGGEGRKRCPSQSSSRPAAMISQPPTPPTGQPVREDAKWTSQHSNTQTLGK--------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9P457-1", "uniprot_id": "A0A8M9P457_DANRE", "id": "A0A8M9P457-1", "name": "", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------MATEVETLPPN-NPLLQPEEPQ-------------------------HKDGEYPLQERHTADSGSPGAG-------------QEEQAAG------------------------REISEAPLPKVNPWTKK------------------------------------------------------------------------MSGVNGQPAAEHSGPTKVVKAGNS----------------------------RLRRGGKVGDFGDTNNWPTPG------------------EIATKEVQVLKK---PTVKREPK------GKRESEESKENLKSKSDDSGEDKN------------TDEESQRSSH------------------RRRGNKQRWVPLMIEVKAEGPRERSASR----NNTRPYDAHRG---------------------THSSRN-----------GLRDWPSERFEQELKDDHDEVSSVKSDGAP-YRAGARGRGRGRGRGRGRGRG--RGHYDY--------------------YSYKGSEGKDGAYAQKFGNSMTYYYDNMSSAELYSVDQDLLKDYIKRQIEYYFSVDNLERDFFLRRKMDEGGFLPVSLIASFHRVQALTT--DVSLILQALKDSKVVDIID-MKMRCKEEPQKWPLPDLCLPDQAQTDFAQFIH---------------------CPEFIPR--HLPASPSPAGTPRSGTPR--------------------------------------------------------SSTPHQELCSLKMMPKGLSASLPDLDSECWIEVKKRPRPSPARP--------------------------------------------------------------------------------KKED---------VRCVLQMGQVSAEEQEEPEELDFMFDEEMQQMD----GRRNTFTDWS--DEDSDCEIDDRDVNKILIVTQTPPYLRKHPGGDRTGHHTSRSKLSSELVKIINDGLFYYEQDLWDDSGEPEYAIIKQEVENFKKVHLISREQFDCLTP--EPPVDPNQEVPPGPPRPTQSKIHTLFPTEALANKLFGAPDPSCMARSLPTTVPDSPSHRSARTPRTPRTPRLKD-AQTPRFYPVVKDGRPLDAKTPRKRKTRHSSNPPMECHVGWVMDSREHRSRTASVSSNASPSEGTAAMGNFG-CTPQSLPKFQHPSHELLKENGFTQHVYHKYRRRCLNERKRLGIGQSQEMNTLFRFWSFFLRDHFNRKMYEEFRQLSVEDGKEGYRYGLECLFRFYSYGLERKFRPDIFKDFQEETVKDYEAGQLYGLEKFWAFLKYSKTKN-MEIEPKLQEHLSKFRRLEDFRVDPPM-EDGVR---------------------------------------------------------------------------------------------------------------KRHSSSG-----DGRRRHPSHPGSRSQTQSQLQPSGAAAGATRDDSRAQSQRDARPPK----------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VAW5-3", "uniprot_id": "LARP_DROME", "id": "Q9VAW5-3", "name": "La-related protein 1", "aln": "MSSKEETPSTGGAAPVATVAASGSATTSYANVVQNLETKKSGTSNTTTTTARATVDNKENQPNLKSFKSWSEEAAAAEAAGESPIVGSVSLAQTGEKRAAASGGDNTAENSSELDDNNDFVPVLSHHRRDRKKARKEKPRDQQPAGGRGDGQKPQQAGGRRVPGSSDTERKSVRPRAPRGGSPRKSAAGAAGAAGSNAGAVSSAVPGGPKVHKDRKDTSPSASIEGAGSSGNEAKSADGDQQAGEKGAAG------AAPPPKRFIAAPPPKVNAWKISAKQSGSPKAGTSPLDKRVLQPKAQQQQQQTKQTASQNNNAQNTASNKKTQQQQQPQQGATTTTQTTTAAAAAATAAAAATAATTSAAAATSSAAAVPAATTETATTTTVDASQADALAKVVVKDKKKVNQKASDFSNVGDWPTLIGGTSGSGKATSNEPKRNPTKKQQSAKTAAAVAASSNTTSSEVATESNVAGTTSSSNSNPSSSTTTTNTTTNSQATTAPVASTSHDAKAQRDAEPAANSAAGTTGTAAGPALTKKIPKHKWRPLPIDLAKSSRPKPIGGRPNRRFSDDIADQRRPPRVYHDRQPGAGGAGVESRHPHAGRHPYGSRPATATSERVDSWRSSSSTTTAAFDEQRSGAAGGAGAAGTGVGSATRGPRRYRTPYRGGRQGRGGFSRQGPGRPTYRIPRHLLASGEYANYLPADAAGADSQSSYVLMGTHYFGNVP-AAYIELDANSIKEAIKKQVEYYFSVDNLTGDFFLRRKMDPEGYIPVTLIASFHRVLALTT--DVAVIVNAIKESDKLELFEGYKVRTKTTPTTWPITEVPEVNEGEPKAIGTLEQEQLEQNDGQEKLEEQTEADSPPPILTSAMATKPLNSIPPPPMPRNPQNLVPKMLQDKQQSRSSTIAALNSVNAISALTQQVEGGAAELAGHLSGLAESVKPKSTSTPDKRNAASAGNGAGSAAALVAEPEGIWKEVKRRSKTNAIKENATTPPQQQQPPLSQTLNNNNDNVKTNNTSSKSKSSSNNAPSNASSSATVCVTTNNASSATKATTKTTTTSTATTTTNNNIKSGNAAYSKTHSKSSSKTAAPPSAQCHAEKEELDFQFDEELMDPLPPGTGRINNFTENFSDDDESDYEFADRDINKLLIVAQVG-RAPKHEGYDRTADFTSRTKITQDLENIINDGLVNYEEDLWTTTN---------VVADYKTVNVISQADFEKLAGGRNKSVLPPQVVPPPPPF-----------EEDLDETLVGDT-------TLNSTLNNTLKSRRARFYAAPNS-------------------HSIDPRTPRKRKLRHTANPPVEAHVGWLLDTVEHRPRTTSMGSSAGTSPTASSYGSFGSSVPQSLPVFQHPSHALLKENNFTQQAYHKYHSRCLKERRRLGYGQSQEMNTLYRFWSFFLRENFNKSMYNEFRSLALEDAGNGFRYGLECLFRFFSYGLEKKFRPNIYQDFQDETIADYETGQLYGLEKFWAFLKYYKNGEKLEVQPKLAEYLKSFKNIEDFRVVEPEINEMLQGVGSLNPGRQLNRHRSVSESDGTAVIAAGGRRLNTTITNRSDYVGRLLQQQHQQQQQQQHHQYQQGYGGYNQQQNRRRTGSFGSTTVRIRSGSLGNKPQVANRNQGSQHELRRGGSNSGLAPHKRQQQQKPKPGAGSQTGSTRATTSAAATATTAASAATSTAATPAVTVSSGSSSSKK", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P25567-1", "uniprot_id": "SRO9_YEAST", "id": "P25567-1", "name": "RNA-binding protein SRO9", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------MSAETAAANTATAPVPEVQEQE------------------------SSKSKQVN-------------------------------------------------------------LTPAPLPTSSPWKLAP------------------------------------------------------------------------TEIPVSTISIEDLDATRKKKNRT---------------------------------------------PTPK-----------------SSTATKWVPIKASITVSGTKRSGSKNGASNGNSNKSKNNKTAASSTSSSNANRK-------------KKHHQHNAK--------------------KQQQMKKDGFESAVGEEDSKDATSQENGQSTQQQQPPHHRN------------------------------------HHHSHHHNSNGPQRRKFHNSNNAGMPQNQGFPPQFKPYQGRN---ARNNNNNRSKYHNHFHHN----------------------------QQHPQQPMVKLQQQFYPVQP--------VLMAINNIARQIEYYFSEENLTVDNYLRSKLSKDGFAPLSLISKFYRVVNMSFGGDTNLILAALR-------------------------------------------------------------------------------------------------------------------------------------------------------EIVANEAATVNVAEGTLAAKEGDNVTGEAKEPSP--------------------------------------------------------------------------------------------------------LDKYFVRSKSWSNWLPETFETEINIEK----------------------ELVGDALDQFMISLPPVPQQEEESSTELASQEQETKEDSAPVAAGESESSL---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . : : ** *. ..*. : . . . : ** : . . . . ...:.. :.: :. : . . *:... : : : : : . . . . . * .. : :. . . * *. * .. : : :: . : * :*:***** :** * :** *:. *: *::**:.*:** :: * :*. *:: : . .:* :.. . . : : * *: *: *: . :::::* .. . : :.. . : : : .:. . ", "identical_positions": 40, "similar_positions": 115, "identity": "2.31%" }, { "cls_id": "homologset.agr.MGI:1890169", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I6AE43-1", "uniprot_id": "A0A8I6AE43_RAT", "id": "A0A8I6AE43-1", "name": "Erbin", "aln": "MTTKRSLFVRLVPCRCLRGEEETVTTLDYSHCSLEQVPKEIFTFEKTLEELYLDANQIEELPKQLFNCQSLHKLSLPDNDLTTLPASIANLINLRELDVSKNGIQEFPENIKNCKVLTVVEASVNPISKLPDGFSQLLNLTQLYLNDAFLEFLPANFGRLTKLQILELRENQLKMLPKTMNRLTQLERLDLGSNEFTEVPEVLEQLSGLREFWMDGNRLTFIPGFIGSLRQLTYLDVSKNNIEMVEEGISTCENLQDFLLSSNSLQQLPETIGSLKNVTTLKIDENQLMYLPDSIGGLRSIEELDCSFNEIEALPSSIGQLTNIRTFAADHNYLQQLPPEIGNWKNVTVLFLHSNKLETLPEEMGDMQKLKVINLSDNRLKNLPFSFTKLQQLTAMWLSDNQSKPLIPLQKETDSETQKMVLTNYMFPQQPRTEDVMFISDNESFNPALWEEQRKQRAQVAFECDEDKDEREAPP----------REGNLKRYPTPYPDELKNMVKTVQTIVHRLKDEETNEESGRDLKQHEDQQVVNKDKGVKPSES-ITTKSKLDEREKYMN--SVPKTSEPEAETNAGNSPVTTNRKSSGNMKHLVNHDDVFEESEELSSDEE-MKMAEMRPPLIETSINQPKVVALSNNKKDDAKDTDSLSDEVTHNSNQNNSNCSSPSRMSDSVSLNTDSSQDTALCSPAKQIPIDSNSKIRQEDENFN------SLLQNGVNLNNSPEEKFKIN---DKKDFKLPEYDLNIEEQLVLIEKDVDSKATSEDSHQLDHINMNLNKLVTNNIFQPEIMERSKMQDIVLGTGFLSIHSKSEAEHIENGNKFLNSESINKVNGLSEDTAQ--SPGRIEPQ-NTSPADVGISKSTEDLSPQRSGPAGSVVKSHSITNMETGGLKIYDILSDDGPQPPGATVKVAST-MDGKNIVRSKSATLLYDQPLQVFTASSSSS-ELLSGTKAVFKFDSNHNPEDPDIIRASIVPGPQSIPQLYGPPQYNVQYSGSAAMKDTLWHPKQNPQIDPVSFPPQRLPRSESAENHSYTKHSANMNFSNHNNVRANTAYHLHQRLAPTRHGEMWAVSPNDRLVPAVS-RTTVQRQSSVSSTASVNLGDPGPTRRT---EGDYLSYRELHSMGRTP-VTSGS-QRPLSARAFSIDGPSTSRPQSARPSISEIPERTMSVSDFNYSRTSPSKRPNARVGSEHSLLDPP--GKSKVPHDWREQVLRHIEAKKLEKSMLSRSFSSNLTAVSSSHYGSSRDLHGSQGSLALNVADGRGSGGHSFRHPQTSSPGDCCQDDRFMSGE--QNHPLGALSHRDLR-DSLMKMPLSNGQMGQPLRPQANYSQTHHPPQASVARHPSREQLIDYLMLKVAHQPPYTHPHCSPRQGHELAKQEIRVRVEKDPELGFSISGGVGGRGNPFRPDDDGIFVTRVQPEGPASKLLQPGDKIIQANGYSFINIEHGQAVSLLKTFHNAVELIIVREVSS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q80TH2-3", "uniprot_id": "ERBIN_MOUSE", "id": "Q80TH2-3", "name": "Erbin", "aln": "MTTKRSLFVRLVPCRCLRGEEETVTTLDYSHCSLEQVPKEIFTFEKTLEELYLDANQIEELPKQLFNCQSLHKLSLPDNDLTTLPASIANLINLRELDVSKNGIQEFPENIKNCKVLTIVEASVNPISKLPDGFSQLLNLTQLYLNDAFLEFLPANFGRLTKLQILELRENQLKMLPKTMNRLTQLERLDLGSNEFTEVPEVLEQLSGLREFWMDGNRLTFIPGFIGSLRQLTYLDVSKNNIEMVEEGISTCENLQDFLLSSNSLQQLPETIGSLKNVTTLKIDENQLMYLPDSIGGLRSIEELDCSFNEIEALPSSIGQLTNMRTFAADHNYLQQLPPEIGNWKNITVLFLHCNKLETLPEEMGDMQKLKVINLSDNRLKNLPFSFTKLQQLTAMWLSDNQSKPLIPLQKETDTETQKMVLTNYMFPQQPRTEDVMFISDNESFNPALWEEQRKQRAQVAFECDEDKDEREAPP----------REGNLKRYPTPYPDELKNMVKTVQTIVHRLKDEETNEESGRDLKQHEDQQVVNKDKCVKTSES-TTTKSKLDEREKYMN--SVQKMSEPEAETNGGNLPVTASMKLSGNLKHIVNHDDVFEESEELSSDEE-MKMAEMRPPLIESSINQPKVVALSNNKKDDAKDADSLSDEVTHNSNQNNSNCSSPSRMSDSVSLNTDSSQDTSLCSPVKQTPVDSNSKVRQEDENFN------SLLQNGVNLNNSPEEKFKIN---DKKDFKLPEYDLNIEEQLVLIEKDIDSKATSDDSRQLDHINMNINKLVTNNIFQPEVMERSKMQDIVLGTGFLSIHPKNEAEHIENGAKFPNLESINKVNGLCEDTAP--SPGRVEPQKASSSADVGISKSTEDLSPQRSGPTGAVVKSHSITNMETGGLKIYDILGDDGPQPPSAAVKIASA-VDGKNIVRSKSATLLYDQPLQVFTAASSSS-ELLSGTKAVFKFDSNHNPEEPDIIRAATVSGPQSTPHLYGPPQYNVQYSGSATVKDTLWHPKQNPQIDPVSFPPQRLPRSESAENHSYAKHSANMNFSNHNNVRANTGYHLQQRLAPARHGEMWAISPNDRLVPAVT-RTTIQRQSSVSSTASVNLGDP--TRRT---EGDYLSYRELHSMGRTP-VMSGS-QRPLSARAYSIDGPNTSRPQSARPSINEIPERTMSVSDFNYSRTSPSKRPNTRVGSEHSLLDPP--GKSKVPHDWREQVLRHIEAKKLEK------------------------------------------------HPQTSSPGECCQDDRFMSEE--QNHPSGALSHRGLP-DSLMKMPLSNGQMGQPLRPQAHYSQTHHPPQASVARHPSREQLIDYLMLKVAHQPPYTHPHCSPRQGHELAKQEIRVRVEKDPELGFSISGGVGGRGNPFRPDDDGIFVTRVQPEGPASKLLQPGDKIIQANGYSFINIEHGQAVSLLKTFHNAVDLIIVREVSS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q96RT1-1", "uniprot_id": "ERBIN_HUMAN", "id": "Q96RT1-1", "name": "Erbin", "aln": "MTTKRSLFVRLVPCRCLRGEEETVTTLDYSHCSLEQVPKEIFTFEKTLEELYLDANQIEELPKQLFNCQSLHKLSLPDNDLTTLPASIANLINLRELDVSKNGIQEFPENIKNCKVLTIVEASVNPISKLPDGFSQLLNLTQLYLNDAFLEFLPANFGRLTKLQILELRENQLKMLPKTMNRLTQLERLDLGSNEFTEVPEVLEQLSGLKEFWMDANRLTFIPGFIGSLKQLTYLDVSKNNIEMVEEGISTCENLQDLLLSSNSLQQLPETIGSLKNITTLKIDENQLMYLPDSIGGLISVEELDCSFNEVEALPSSIGQLTNLRTFAADHNYLQQLPPEIGSWKNITVLFLHSNKLETLPEEMGDMQKLKVINLSDNRLKNLPFSFTKLQQLTAMWLSDNQSKPLIPLQKETDSETQKMVLTNYMFPQQPRTEDVMFISDNESFNPSLWEEQRKQRAQVAFECDEDKDEREAPP----------REGNLKRYPTPYPDELKNMVKTVQTIVHRLKDEETNEDSGRDLKPHEDQQDINKDVGVKTSESTTTVKSKVDEREKYMIGNSVQKISEPEAEISPGSLPVTANMKASENLKHIVNHDDVFEESEELSSDEE-MKMAEMRPPLIETSINQPKVVALSNNKKDDTKETDSLSDEVTHNSNQNNSNCSSPSRMSDSVSLNTDSSQDTSLCSPVKQTHIDINSKIRQEDENFN------SLLQNGDILNSSTEEKFKAH---DKKDFNLPEYDLNVEERLVLIEKSVDSTATADDTHKLDHINMNLNKLITNDTFQPEIMERSKTQDIVLGTSFLSINSKEETEHLENGNKYPNLESVNKVNGHSEETSQ--SPNRTEPHDSDCSVDLGISKSTEDLSPQKSGPVGSVVKSHSITNMEIGGLKIYDILSDNGPQQPSTTVKITSA-VDGKNIVRSKSATLLYDQPLQVFTGSSSSS-DLISGTKAIFKFDSNHNPEEPNIIRGPTS-GPQSAPQIYGPPQYNIQYSSSAAVKDTLWHSKQNPQIDHASFPPQLLPRSESTENQSYAKHSANMNFSNHNNVRANTAYHLHQRLGPARHGEMWAISPNDRLIPAVT-RSTIQRQSSVSSTASVNLGDPGSTRRAQIPEGDYLSYREFHSAGRTPPMMPGS-QRPLSARTYSIDGPNASRPQSARPSINEIPERTMSVSDFNYSRTSPSKRPNARVGSEHSLLDPP--GKSKVPRDWREQVLRHIEAKKLEK-----------------------------------------------KHPQTSSSGDPCQDGIFISGQ--QNYSSATLSHKDVPPDSLMKMPLSNGQMGQPLRPQANYSQIHHPPQASVARHPSREQLIDYLMLKVAHQPPYTQPHCSPRQGHELAKQEIRVRVEKDPELGFSISGGVGGRGNPFRPDDDGIFVTRVQPEGPASKLLQPGDKIIQANGYSFINIEHGQAVSLLKTFQNTVELIIVREVSS", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M2B233-1", "uniprot_id": "A0A8M2B233_DANRE", "id": "A0A8M2B233-1", "name": "", "aln": "MSSKRSLFVRLVPCRCLRGEEETVTTLDYSHCSLEQVPKEIFSFEKTLEELYLDANQIEELPKQLFNCQLLYRLSLPDNDLTVLPPGIANLINLRELDVSKNGIQEFPENIKNCKVLAIVEASVNPISKLPEGFTQLLSLSQLYLNDAFLEFLPASFGRLTKLQILELRENQLKMLPKSMHKLTQLERLDLGSNEFTEVPEVLEQLTGIRELWMDGNKLTFVPGMIGALKQLSYLDVSKNNVEMVEEQISGCENLQDLLLSNNALTQLPGSIGSLKKLSTLKVDDNQLMYLPDTIGGLSHLDELDCSFNEIEALPSSIGQCVNLRTFAADHNLLAQMPPEMGSLKNVTVLFLHSNKLENLPEEMGDMQKLKVINLSDNKLRNLPYSFTKLNQMTAMWLSENQSKPLIPLQKEEDPETHKIVLTNYMFPQQTRTEEYVPNSDSESFNPSLWEEQRKQRAQVAFECDEDKDEREMPPRVSSHRPLLSREGNLKRYPTPYPDELKNMVKTAQSVAHRLKEDESGDEAGKEPRVSERNHIGVQDVGVKVIESPCTNGKPAEMDPKAAMN--SNHNYEPIDSVDNHSIERIP-LKTSDNMRTMVNHDDTLEDSEELSSEEEEMKIAEMRPPLIEISINQPKVVALSKDKKDDGKDADSLLDETVANSNQNNSNCSSPSRMSDSVSLTTDSSQDNSLCTPERESKMPLIPKNGQEDENLNQLKQMTPLLQNCNGSETSLQTILKNQQSYESKSDQMADYSFSMEERLALIEKGINNGVTDQYS-KWDQINMNVAKLSPDNMLAYEELERTKSP-PAKETMSSNNNARLSLENLENGNQLQKTQSGENFNSRTDQVPLRYESVRTVSTGVNALSDMSLSRSTEELSPEKKCPPAPVVKSQSIANMDGGGMKLYSIEGESPPYEVACASRTSVAGAQGQSIVRSKSASLLNDQHMQIYPGSSASSSDLLSSSKP--PVSSTRYPAGP-------------------PPQYNIQYASSTVPKDNLWSQRTPVPPDQPYMPPQHS--------------LANTNFSNRNNAPP---YPQPQQRGPPKTPDMWAK---ERMLPQVGQRGTLQRQGSGSSGNPMCMPDP---RRMPGMEGDYMTYRDIHAAGRGPLQMSQALHRPLSARTYSMDGPNAPRPQSARPPPHEVPERTMSVSDFIYQQGSPSKRSNMRVKSEHSLLDGPVGGGGRVPADWRDQVMRHIEAKKMEKSTLSRS--------------------------------------LATLNGSQSSLAFSAVDGWQFGAHGPSDDVFSPHGQQGYHIDTLRKVPLMNGQMCPPVRSPMSCTQP------PMARHPSREQLIDYLMLKVSQQPPGPQ-----RVPHETLQQEVHVKIEKNPELGFSISGGIGGRGNPFRPDDNGIFVTRVQSEGPASKLLQPGDKILQANGYSFVNIDHGHAVSLLKTFPNTVDLIIVREMAA", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9V780-1", "uniprot_id": "LAP1_DROME", "id": "Q9V780-1", "name": "Protein lap1", "aln": "----MPLLSKCFPCFKFK-REEVIDKLDYSNTPLTDFP-EVWQHERTLEELYLSTTRLQALPPQLFYCQGLRVLHVNSNNLESIPQAIGSLRQLQHLDLNRNLIVNVPEEIKSCKHLTHLDLSCNSLQRLPDAITSLISLQELLLNETYLEFLPANFGRLVNLRILELRLNNLMTLPKSMVRLINLQRLDIGGNEFTELPEVVGELKSLRELWIDFNQIRRVSANIGKLRDLQHFEANGNLLDTLPSELSNWRNVEVLSICSNSLEAFPFSVGMLKSLVTFKCESNGLTELPDSISYLEQLEELVLSHNKLIRLPSTIGMLRSLRFLFADDNQLRQLPDELCSCQQLSVLSVANNQLSALPQNIGNLSKMKVLNVVNNYINALPVSMLNLVNLTSMWLSDNQSQPLVPLQYLDAS--TKTQLTCFMLPQVT-------------FKMNSIQAQQQAQEQYEFVYANQQQPHASPS----------RRICFAEEATILSNAKAQPAPNYPSFVAAPPTPTPDQMAG----------------SVRLMRSPTPYPKELRQMSKYVR---------------------------------------------------------------------QAQAATSSANASEVREARVVTNGQIHCDSNNANQDVVDQATTSAIYGIAPETTHIYGVYQQPQQMAHPVP----------------------------------------TQEYYGLPLVNYEAHYQQLYVEANTP----------LPTTHLNGDQDYELQPLQQQPMQQQALPTPRLEPPPYHIARVYTKKTPEDLNLYESMRQRKQQQQLQEQTIYQDALNSNSNFKTTAIGAQDVEESVDQLDYQN-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------NISNNLEPNPEEEDQELDDTMSQHSLNSTATNNTSKASHKKSTWIFGVHKNPTVK------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------QVTLKWENSIGFDIAELLN---------QVGIFVSSITPNTNAARLLNLNDKLLEIDGYDLTNANLSDAKRVLLNCGTVMNIMLSRK---", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .*: : .** :: .**.: .****: .* :.* *:: .*:*******.:.::: ** *** ** * * : .*:* :* .*..* :*:.**:.:* * :.**:**.** *: :: * *.:.:**:.::.*:.* :* **:::******.****.:*:***** *:* ***:* :* :*:***:*.*****:***: :*..::*:*:* *:: :.. ** *::* :::.. * :: : . :* .*:: : :..*:* :* ::* **.: *:* :.* * ***:*. * ::** *.*:: ***:** .:* : **.* * *:* *: . ::::** : *:*. **:::*::.*:**:*: :* :. ** *: :* ::*:****:***:**:*** . * ** :*:** . *: : *:: : * * :::: : *. *. : . .* .: : . . :.. ..: :* *: .* . . * *.:..: * : .: : .: :**: *.: . : * .: .:::: .: :: .: :. . . . : :* . ::* : : : : ::: . : *: . .. :: : ::. . .:..*.::*. :. .:.. ..*:. : .: * . ..*:: . : . *. :* :: : .:**.*: :. : ****: : .: *::**: .**::: :**.: * : ..* :* . ..::::: *: ", "identical_positions": 215, "similar_positions": 317, "identity": "14.43%" }, { "cls_id": "homologset.agr.MGI:1890212", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I5Y6B0-1", "uniprot_id": "A0A8I5Y6B0_RAT", "id": "A0A8I5Y6B0-1", "name": "Protein-serine O-palmitoleoyltransferase porcupine", "aln": "----------------------------------------------------------MATFSRQEFFQQLLQGCLLPTVQQGLDQIWLLLTICFACRLLWRLG------LPSYLKHASTVAGGFFSLYHFFQLHMVWVVLLSLLCYLVLFLCRHSSHRGVFLSVTILIYLLMGEMHMVDTVT-WHKMRGAQMIVAMKAVSLGFDLDRG--EVGAVPSPVEFMGYLYFVGTIVFGPWISFHSYLQAVQGRPLSRRWLKKVARSLALALLCLVLSTCVGPYLFPYFIPLDGDRLLRNKKRKARGTMVRWLRAYESAVSFHFSNYFVGFLSEATATLAGAGFT-EEKDHLEWDLTVSRPLNVELPRSMVEVVTSWNLPMSYWLNNYVFKNALRLGTFS------AVLVTYAASALLHGFSFHLAAVLLSLAFITYVEHVLRKRLAQILSACILSKRCLP-------DCSHRHRLG----LGVRALNLLFGALAVFHLAYLGSLFDVDVDDTTEEQGYGMAYTVHKWSELSWASHWVTFGCWIFYRLIG", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9JJJ7-1", "uniprot_id": "PORCN_MOUSE", "id": "Q9JJJ7-1", "name": "Protein-serine O-palmitoleoyltransferase porcupine", "aln": "----------------------------------------------------------MATFSRQEFFQQLLQGCLLPTVQQGLDQIWLLLTICFACRLLWRLG------LPSYLKHASTVAGGFFSLYHFFQLHMVWVVLLSLLCYLVLFLCRHSSHRGVFLSVTILIYLLMGEMHMVDTVT-WHKMRGAQMIVAMKAVSLGFDLDRG--EVGAVPSPVEFMGYLYFVGTIVFGPWISFHSYLQAVQGRPLSRRWLKKVARSLALALLCLVLSTCVGPYLFPYFIPLDGDRLLRNKKRKARGTMVRWLRAYESAVSFHFSNYFVGFLSEATATLAGAGFT-EEKDHLEWDLTVSRPLNVELPRSMVEVVTSWNLPMSYWLNNYVFKNALRLGTFS------AVLVTYAASALLHGFSFHLAAVLLSLAFITYVEHVLRKRLAQILSACILSKRCLP-------DCSHRHRLG----LGVRALNLLFGALAIFHLSYLGSLFDVDVDDTTEEQGYGMAYTVHKWSELSWASHWVTFGCWIFYRLIG", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9H237-1", "uniprot_id": "PORCN_HUMAN", "id": "Q9H237-1", "name": "Protein-serine O-palmitoleoyltransferase porcupine", "aln": "----------------------------------------------------------MATFSRQEFFQQLLQGCLLPTAQQGLDQIWLLLAICLACRLLWRLG------LPSYLKHASTVAGGFFSLYHFFQLHMVWVVLLSLLCYLVLFLCRHSSHRGVFLSVTILIYLLMGEMHMVDTVT-WHKMRGAQMIVAMKAVSLGFDLDRG--EVGTVPSPVEFMGYLYFVGTIVFGPWISFHSYLQAVQGRPLSCRWLQKVARSLALALLCLVLSTCVGPYLFPYFIPLNGDRLLRNKKRKARGTMVRWLRAYESAVSFHFSNYFVGFLSEATATLAGAGFT-EEKDHLEWDLTVSKPLNVELPRSMVEVVTSWNLPMSYWLNNYVFKNALRLGTFS------AVLVTYAASALLHGFSFHLAAVLLSLAFITYVEHVLRKRLARILSACVLSKRCPP-------DCSHQHRLG----LGVRALNLLFGALAIFHLAYLGSLFDVDVDDTTEEQGYGMAYTVHKWSELSWASHWVTFGCWIFYRLIG", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M3B1X0-1", "uniprot_id": "A0A8M3B1X0_DANRE", "id": "A0A8M3B1X0-1", "name": "", "aln": "----------------------------------------------------------MGSLSRQAFFQELGSGCLLPTVQQGLEQVWQLLLICLVCRLSWRLG------LPNFLKHLSTVVGGFYTLYLFFELHMVWVVLLSLLCYLILFLCRHSSSRGPFLSITILIYLLLGELHMMDTTT-WHKMRGSQMVVAMKAVSLAFDLDKG--IVDKVPSPVEFMGYIYFVGTVIFGPWISFNSYMDAVESRKLSVSWFMKSVISCVKSQLCLLISNCVAPYLFPYFIPVFGNKLLRNKKRKMRGSIKRWLQAYENSLSFHFSNYFVSFLGETTTTLAGAGFT-EEKDNLKWDMTIAKPLYVEFPRSMVEVVTSWNLPMSRWLNTYVFRKALRYGSFT------AIIMTYTASALLHGLSFHIGAVLLTLGFITYIEHVLRKRLSAILNACVLSKRCPS-------DCKHRHKKE----LWVYLINGTFSMLALLHLTYLGSVFGSSSDDMDSDEDGVASHTIQKWTQLSWTSHWLTFALWVFYRLIL", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VWV9-1", "uniprot_id": "PORCN_DROME", "id": "Q9VWV9-1", "name": "Protein-serine O-palmitoleoyltransferase porcupine", "aln": "MDYQYFEEESDYIDLDEEEEDDDVVTAGSLDHRFGQPNGEEDYYFGGDDVEEELVVDGHGVLELAGRLLESLQSCVQPSVLQVMQYVAPMLLLCLLCRLLCLLYSQRRRLTSLAPLHLFHFACGLIILQITVGYRLLLLLLLAAVGYLLLQLLRLGRRGAQVLAVLTVGSQFLYELLIWRRRSDWPQLRGIQMVVNMKLISLGFDLTASGQLQARIPGPFAYLGYIYSPATCALGPWVSFGCYMDCLVPRNSWLVSLRRLLPNVVICVLAVTVSNCVAPALSDFFG-----------------DSSHFLVMYWDALSVRSSHYFVGMMAQALLVASDQRLDGATKESDMLGPLISQPWRIEWPRSISSLVRSWNIPMHEWLKRYIYAPCKPTASTSRGRILVVVLSTYLVSSLLHGMDLRIYLVLISLAFLAEGESLLRRQLASLLNACITANLCPGKERCRYSHCPSKRRLNSLSYWLARLTNLAFTALAIFHLAYLGVVLLGDDLEVGEDGD----SFLWHWQQAGYLSHYIGLGTFVLYLFIS", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . :. : : ..*: *:. * :: : :* :*: *** * . * .. *: * . ::: ::**: : **:* * * . . .*:: : :: *: : : * ::** **:* ** :**.*** . :*.*. ::**:* .* :***:** .*::.: * : : . . . *.: :*.**.* * :* ::* * .::*.: *:***.::.:: . :. : *: . :::* :* ***: .:* ***:** **: *:: . .: : .:: ** .*:****:.::: **::*.*:: * :**::*: :*.**: :: * .* ::: . * * **::**:*** :: . : .: . : :* : .: **:: :. :::* :* ", "identical_positions": 110, "similar_positions": 158, "identity": "20.15%" }, { "cls_id": "homologset.agr.MGI:1890215", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0ABK0LA20-1", "uniprot_id": "A0ABK0LA20_RAT", "id": "A0ABK0LA20-1", "name": "E3 ubiquitin-protein ligase RNF25", "aln": "MGPWQRFSDISKGLRVLPSEVEVLESIYLDELQVMKGNGR-SPWEIFITLHPATAEVQDSQFVCFTLVLQVPVQYPHEVPQISIRNPRGLSDEQIHKISQALGHVAKEGLGTAMLYELIEKGKEILTDNNIPHGQCVICLYGFQEKEAFTKTPCYHYFHCHCLARYIQHMEQELNTQ--EQEQ--QHVVTKQKAVGVQCPVCREPLVYDLASLKAAPEPQQP--MELYQPSAESLRQQEELKRLYQRQQEKGGIIDLEAERNRYFISLQQPPAALEPESVVDVSRGPQP----PNTLSAEQSTSLAAQSTLPTPLPMATQYVYEKTSGAGPNQQRLGETQKSMLDPPRPGRGSWRQYDR--RHPKGGECCAP-----KGTSEIQELPPPEKPLKETVD-----------LKAEPRNKG------------------LTGHPQ--------EKGP-------GSWQ-----GPSARRTRDCARWERSKNRTPGSSYPHLPRGQGAYRSGTRREPLGLE---SEEGS-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9QZR0-1", "uniprot_id": "RNF25_MOUSE", "id": "Q9QZR0-1", "name": "E3 ubiquitin-protein ligase RNF25", "aln": "MAASASTAAGEE-DWVLPSEVEVLESIYLDELQVMKGNGR-SPWEIFITLHPATAEVQDSQFVCFTLVLRIPVQYPHEVPQISIRNPRGLSDEQIHKISQALGHVAKEGLGTAMLYELIEKGKEILTDNNIPHGQCVICLYGFQEKEAFTKTPCYHYFHCHCLARYIQHMEQELTTQ--EQEQERQHVVTKQKAVGVQCPVCREPLVYDLASLKAAPEPQQP--MELYQPSAESLRQQEELKLLYQRQQEKGGIIDLEAERNRYFISLQQPPAALEPESAVDVSREPQP----PNALSAEQSTSLADQSTLPTSLPMTTQYTYEKTSGAGPNQQRPGETQKSVLDPPRHGRGSWRQYDR--RHPKGGECCTP-----KGTSEIHELPPPEKPLKETVD-----------LKAEPRNKG------------------LTGHPQ--------EKGP-------GSWQ-----GPSARRTRDCARWERSKNRTPGSCYPHLPRGQGAYRSGTRREPLGLE---SEEGS-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q96BH1-1", "uniprot_id": "RNF25_HUMAN", "id": "Q96BH1-1", "name": "E3 ubiquitin-protein ligase RNF25", "aln": "MAASASAAAGEE-DWVLPSEVEVLESIYLDELQVIKGNGRTSPWEIYITLHPATAEDQDSQYVCFTLVLQVPAEYPHEVPQISIRNPRGLSDEQIHTILQVLGHVAKAGLGTAMLYELIEKGKEILTDNNIPHGQCVICLYGFQEKEAFTKTPCYHYFHCHCLARYIQHMEQELKAQGQEQEQERQHATTKQKAVGVQCPVCREPLVYDLASLKAAPEPQQP--MELYQPSAESLRQQEERKRLYQRQQERGGIIDLEAERNRYFISLQQPPAPAEPESAVDVSKGSQP----PSTLAAELSTSPAVQSTLPPPLPVATQHICEKIPGTRSNQQRLGETQKAMLDPPKPSRGPWRQPER--RHPKGGECHAP-----KGTRDTQELPPPEGPLKEPMD-----------LKPEPHSQG------------------VEGPPQ--------EKGP-------GSWQ-----GPPPRRTRDCVRWERSKGRTPGSSYPRLPRGQGAYRPGTRRESLGLE---SKDGS-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q7SXJ6-1", "uniprot_id": "RNF25_DANRE", "id": "Q7SXJ6-1", "name": "E3 ubiquitin-protein ligase RNF25", "aln": "MAAES----------DVLSEIEVLQSIYLDELNVTQNDEG--GWTVSLVLHPSTAEDCLSQFVRLTLTMDLDSQYPYSSPYISIHNPRGLSDDKLLSLQKSLQMEAEECVGTPVLYQLIERAKEILTDSNIPHGNCVICLYDFKEGEVFTKTSCYHYFHSHCLGRYITHSEMELKDRERELEEDKTRDRTEEEELAVVCPVCRESLTYDLDALLSSPAPVLCQ-QEDAVIGGEFKKKWEALQKILERQKEKGGVIDPEAESNRFLIHINEAPVNLSDTPGMTDSSGAESSQSLPSSSPDSTSTTQTSQNQHTAGQPQRKHTGDFKRGRRGRGAGRGGPARHMVPAPGEERLGKHIQSSDKINSANSGPTNTTSQVESTAQRQACELSENTAQLRQPLTNEENKPVSQDMLTSEPKDGQEVSQQKECISKEVTQTILQEGHPEREHVGRGDKRGSRGSARHHGHWQDRNYKGPGHWDNSGSAGHRGGAYRTREGGAGRGHRGGGAYRGGGRGMHQRVEKEFRKEGVL", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A1Z9I6-1", "uniprot_id": "A1Z9I6_DROME", "id": "A1Z9I6-1", "name": "E3 ubiquitin-protein ligase RNF25", "aln": "-------------MDALQDEVESLEAILMDDVCIKRTPSG-EVEQIETTVLPLTGEEEEQQYVCVTLQVHPTPGYPEESPTFKLLRPRGLDDARLEAIRSACNAKIKESIGFPVVFDLIEVVREHLSGSNLPSGQCVVCLYGFADGDEFTRTECFHYLHSYCLARHLNALRRNYQEEFDKLPAWLQKTADP---FQALCPVCREHIGDETDSLKCAMPPSELLNAPEFKVTEELRQMQQRMSELYLQQKSRGAIIDVNAEG--------SAVISIETEEDIRRRRRREE-------------------AEAAKKLEGPSKEEVIKPTTSSTFAPVVQETHRIMPEPTNNNYHHNRRHYR-------------------GGRRHHHHHQHGHHHRAERE-------------------------------------------------------------------------RGEQNAAAAPANAGGSTSNAVNTNSKQAKAQSASSGLAR----------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : .*:* *::* :*:: : : : .: * *.* .*:* .** : ** . * :.: .****.* :: : . : :* .::::*** :* *:..*:* *:**:***.* : : **:* *:**:*.:**.*:: . : . : : . . ****** : : :* .: * * : : . : :*:.:*.:** :** .. . : : . .: * ::: : * . : . . : . . . . : :. .* * ", "identical_positions": 64, "similar_positions": 101, "identity": "12.17%" }, { "cls_id": "homologset.agr.MGI:1890216", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9JMA9-1", "uniprot_id": "S6A14_MOUSE", "id": "Q9JMA9-1", "name": "Sodium- and chloride-dependent neutral and basic amino acid transporter B(0+)", "aln": "-------------MDRLKCP--------------NFFKCRQKEK-VTASSENFHVGENDEN-QERGNWSKKSDYLLSMVGYAVGLGNVWRFPYLTYTNGGGAFLIPYAIMLALAGLPLFFLECSLGQFASLGPVSVWR-ILPLFQGVGITMVLISVFVAIYYNVIIAYSLYYLFASFQSVLPWANCS-SWADENCSRTPIVTGCNVSIG-----AGEMFMNISWVNTNNLTCLNGSEVFRPGQLPSEQYWDKVTLQRSSGMDE-TGVVVWYLALCLLLAWLIVGAALFKGIKSSGKVVYFTALFPYVVLLILLIRGATLEGASKGISYYIGAQSNFTKLREAEVWKDAATQIFYSLSVAWGGLVALSSYNKFNNNCYSDAIIVCLTNCLTSVFAGFAIFSILGHMAHISGKE-VSQVVKSGFDLAFIAYPEALAQLPAGP-FWSILFFFMLLTLGLDSQFASIETITTTFQDLFPKAMKRMRVPITLGCCLILFLLGLLCVTQAGIYWVHLIDHFCAGWGILIAAILEIAGIIWIYGGNRFIEDIEMMIGAKRWIFWLWWRACWFVITPILLSAILVWSLVKFHRPDYADIPYPDWGVALGWCMIIFCIIWIPIMAIIKIVQAEG--NILQRIISCCRPASNWGP--------YLEKHRGERYRDMAEPAKETDHEIPTISGSTKPE-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9UN76-1", "uniprot_id": "S6A14_HUMAN", "id": "Q9UN76-1", "name": "Sodium- and chloride-dependent neutral and basic amino acid transporter B(0+)", "aln": "-------------MDKLKCP--------------SFFKCREKEK-VSASSENFHVGENDEN-QDRGNWSKKSDYLLSMIGYAVGLGNVWRFPYLTYSNGGGAFLIPYAIMLALAGLPLFFLECSLGQFASLGPVSVWR-ILPLFQGVGITMVLISIFVTIYYNVIIAYSLYYMFASFQSELPWKNCS-SWSDKNCSRSPIVTHCNVSTVNK-GIQEIIQMNKSWVDINNFTCINGSEIYQPGQLPSEQYWNKVALQRSSGMNE-TGVIVWYLALCLLLAWLIVGAALFKGIKSSGKVVYFTALFPYVVLLILLVRGATLEGASKGISYYIGAQSNFTKLKEAEVWKDAATQIFYSLSVAWGGLVALSSYNKFKNNCFSDAIVVCLTNCLTSVFAGFAIFSILGHMAHISGKE-VSQVVKSGFDLAFIAYPEALAQLPGGP-FWSILFFFMLLTLGLDSQFASIETITTTIQDLFPKVMKKMRVPITLGCCLVLFLLGLVCVTQAGIYWVHLIDHFCAGWGILIAAILELVGIIWIYGGNRFIEDTEMMIGAKRWIFWLWWRACWFVITPILLIAIFIWSLVQFHRPNYGAIPYPDWGVALGWCMIVFCIIWIPIMAIIKIIQAKG--NIFQRLISCCRPASNWGP--------YLEQHRGERYKDMVDPKKEADHEIPTVSGSRKPE-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F6NN04-1", "uniprot_id": "F6NN04_DANRE", "id": "F6NN04-1", "name": "Transporter", "aln": "--------MKDYSLKNIRGV--------------LFKNSVGDEQDKDKSDKAEHVVQNDEN-SDRGNWSSKREYMLSMIGYAVGLGNVWRFPYLAYKHGGGAFLIPYTIMLAVSGLPLFFMESSFGQFCSQGPINVWK-AVPILQGVGITMMLVSTFVAIYYNVIIAYSIYYLFASFQDPLPWS----------------IKNCNTTAS-----------NISTAAVN-VSCGQIS-----GQSLSEKYWDEVALQRSSSMDE-TGPVVWHLALCLLLSWILVGAALFKGIKSSGKVVYFTATFPYIVLLILLIRGATLEGAKDGIEFYIGSQSNLTKLAEAEVWKDAATQIFFSLSIAWGGLMALSSYNKFYNNCYQDSIVVCVTNCGTSIFAGFAIFSVLGHMAHVYQRP-VSEVADAGFALAFIAYPDALSKLPISP-LWSILFFFMLITLGLDSQFAGIEVISTCLLDAYPEVLKSKRGLVTTAVCIILFLLGLPCVTRAGIYWVNLIDTFSAGWILLVAGLLEVLGLCILYGGNRFIKDIEMMIGTKSSLFWLWWRACWFFITPVVLSIILIWSLYTFTSPTYSSVAYPDWGISLGWCITAFSLMWIPIVAVWKVCKARG--GLWQRIKSACSPTEDWGP--------YLECHRGERYG----TRGETDPNIFVISNKVSTRL----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9W1J0-1", "uniprot_id": "Q9W1J0_DROME", "id": "Q9W1J0-1", "name": "Transporter", "aln": "--------MGQSSKSGSAGVGGVGGGGGVVCPSTAISGCASGTALIQLDATGPGAGGAGESEHERGTWTGRFDFLLSLLGYSVGLGNVWRFPYLCYNNGGGAFLIPFTIMLVIAGLPLMFMELSFGQYAALGPVAVYRRFCPLFRGLGTGMILVSAIVMLYYNLIIAWTIFYMFASFAPVLPWQNCEPAWSTKYCFSYAQADQCEATNG---TYYLRTCHNATSAAENNITTLALG---ALKRPPAEEYFNNFVLGLSKGIEE-TGSIKLSLAACLFLAWTIVFLCLCKGVQSSGKVVYFTALFPYVVLVILFVRGVTLPGASTGILFYLTP--DWKQLANAQVWGDAAVQIFFALSPAWGGLITLSSYNKFSNNCYKDSLIVAFCNIATSFFAGLVIFSIIGFLAHELNVD-VEKVVDQGAGLAFIVYPEVVTRLPVSP-VWAVLFFVMLLTLGLDSQFALMETVTTAILDRFPN-LRQYKIWVVLSVAIFGYIGGLGFTTNSGMYWLQLMDKYAANWSVLLIAISECILIAWIYGSQRFLNDIQGMIGKRSWFWNFFWGIMWRYITPATLLFILFFNWVEYKPAKYGHYVYPMWADAVGWIVGLLPVLVIFLVAFQEIWRAPMSLSFRDRIKHLLQPTAEWGPAGRPCVNLHAERYQSQNYDGVTNTKILIEEEASPKQAANKKDRQLTLDVDVDVECLPLATVGKRPGAPKSMGKQGSSGNLQTNAKNGTHKSPTTEISPSKQPLIPSEKDNKSANIKVLAAGTQSSGRECTTMSTFAGGGEKKSTKVNLATGATSAAAPLASSNIATAATVAAATKSPPAAGVAPTTLVGIAATGTTVAAAANGKATLKTTISSGAVAATAAGGNKAASVAAATATVAAGKTPAAAMALNVAASVKVSQTDKTAPLKTTISASVATAPGGTKASTAPSVATAAVVSVSSGATVPAAASKAAAPLKATAPPPSLAAVNATQAAKSTPVAAASALVASAPPAKSTSASVAKTNTNAGSKPTATLSTCKSDAPAAAASVGVTNGKVTPSGGATSTAQPAVNQKATAAAAAQKSQGATATATPTKTALNQKTIVPSAGSGKGDVPSSRSTDTPPPAKGAASSNISAKSTKAGKTQANETSPTKSAVKPIKAGSTSPTKAVVSKPGASAAKTAAASAATATATAAGSSSSNKKAATSTAATLGSQAKTKGNASGAGTKK", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9W4C5-1", "uniprot_id": "NAAT1_DROME", "id": "Q9W4C5-1", "name": "Sodium-dependent nutrient amino acid transporter 1", "aln": "-------MELKGVQPSNGSS--------------NGSGNG------ATNAASTEKTDAEKPTAERTNWGNGLEFLMSCISVSVGLGNVWRFPFTAYENGGGAFLIPYIIVLFLIGKPMYYLEMIMGQFTSQGTVKIWS-VVPGFVGVGYGQAFGTICIISYYSSLLALTLYYLFVSFQSELPWSYCR----------DEWTN-CVNSRPQEYVDNLLTGVSLANESARNLSGIVANDETEKLQSSSELYFLNVVIKEKLDISDGVGDPDWKLTLALFVAWVVIFLVIMRGVKSSGKAAYFLALFPYVVLFVLLIRAVTLEGARDGILFFLEP--QWGELLNPTVWKEAVVQCFFSLAVGSGPIIMFASYNRFDHGIYRDAMIVTTLDTLTSLLGGITIFAILGNLAHNLQIENIRDVVRSGTGLAFISYPDAISKFQAVPQLFSVLFFFMLFVLGIGSIVALQSTIVTIICDQFKG---WKYWKVALTTSVCGFLMGLVYVTPGGQWILTLVDFYGGTYVVFILAIFELAGIVWVYGLQNFCDDIEFMCNRR---VSLYWRVCWSFFTPVMMIIIFIYSMVTIEPIKYSELYFPEAANIAGWLLFAIGAAQFPLWGLWYISRHPQG-TYWKSLKASLKPSDRWGPAN------PEIRREWVIFKNQKAAQRATQKDTSKLGFFWRKVANFCGSNK---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VSV2-1", "uniprot_id": "Q9VSV2_DROME", "id": "Q9VSV2-1", "name": "Transporter", "aln": "MKDLKTEILVSGGLPKLETS--------------RCAGSGEALLKPSLLPMALESSELSPDRKARDNWGSSLEFLMSCIALSVGLGNVWRFPFTALENGGGAFLIPYLVVLFVVGKPIYYMEMLLGQFSSRGIVQVFD-FAPLMRGVGYAQLLALGVLATYYASVMALTLRYFFDSFASELPWSFCR----------EEWGDGCVSAS---------GGQPLQGQLSRNFS------------SSTQLYLQRIVLNETDSLEEGIGYPSGSLALMLGISWLTVTLIIIRGVKSSGKAAYVLALFPYVVMFILLVRALTLPGAYDGVMYFLTP--QWEKLLEPQVWYNAVTQVFFSLAVCFGVIIMYSSYNRFGHNVYRDANIVTTLDTFTSLLSGVIIFGILGNLAHESGTKDIASVVKAGPGLAFISYPDAIAKFKMFPQVFSLLFFAMLFMLGVGSNVGMVSCIMTVLKDQFVN---VKLWIIVVSLSVIGFLVGLIYITPGGQHIITLMDFHGVTFVSLVSAIFELIAVGWIYGTKRLCQDAEYMLNIK---TSNYYRICWSIVTPLVMLVILVYSLLTMRPLSYNGQEFPLVYRVVGWCVSGCIIGQLFYWAGYANFKQPKG-SLKSRINNSIKPHSDWGPSD------PKKLMDYQMFLRNKDEE--NSKNVNRRCVCYTAGDRIFG------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * .* ::::* :. :**********: :********: ::* : * *: ::* :**: : * : :: * : *:* : : ** ::* :: *:* ** *** * : . .: :: * ...: . .:.: * *: * ::* : : :*::****..*. * ***:*:.:*::*. ** ** *: ::: . : :* :. ** :*..* *::*: * :: :***:* :. : *: :* : **.:.*. **.::* :** : .*. * **** **:.:::: * .:::*** **: **:.* .. . : * : * : :. .: :: ** * .* : *:* . : :: .: * : :** :.: .* : * . : :: * .** : *:.:. * :* ** : : . : . : * *** : . : ", "identical_positions": 129, "similar_positions": 162, "identity": "10.68%" }, { "cls_id": "homologset.agr.MGI:1890218", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I5ZY40-1", "uniprot_id": "A0A8I5ZY40_RAT", "id": "A0A8I5ZY40-1", "name": "A-kinase anchor protein 10, mitochondrial", "aln": "MRGAGPSPRHSPRALRPDPGPAMSFFRRKVKGKEQEKNLDVKSIKASIAVHSPQKSTKN-HALLEAAGPSHVAINAISANMDSFSSSRTATLKKQPSHMEAAHFGDLGRSC--------LDYQTQETKSSLSKTLEQVLRDSVVLPYFLQFMELRRMEHLVKFWLEAESFHSTTWSRIRAHSLNTVKQSSLAEPVSPSKKQETTASFVTESLDRRLGDSSSAPLLLTQSEGTDLSSRTQNTQNHLLLSQECHSTHSLHHEVARTGTHQISTDSQESSSRLAVASRN-SCSSPLRELSEKLMKSIEQDAVNTFTKYISPDAAKPIPITEAMRNDIIAKICGEDGQ-----VDPNCFVLAQAVVFSAMEQEHFSEFLRSHHFCKYQIEVLTSGTVYLADILFCESALFYFSEYMEKEDAVNILQFWLAADNFQSQLAAKKG-QYDGQEAQNDAMILYDKYFSLQATHPLGFDDVVRLEIESNICREGGPLPNCFTTPLRQAWTTMEKVFLPGFLSSNLYYKYLNDLIHS---VRGDEFLGGNVSLAAHGSVCLPEESHS---------GGSDGSTA--QSSVKKASIKILKNFDEAIVVDAASLDPESLYQRTYAGKMSFGRVSDLGQFIRESEPEPDVKKSK--------GFMFSQAMKKWVQGNTDEAQEELAWKIAKMIVSDVMQQAHHDQPLEKSTKL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O88845-1", "uniprot_id": "AKA10_MOUSE", "id": "O88845-1", "name": "A-kinase anchor protein 10, mitochondrial", "aln": "MRGAGPSPRHSPRALRPDPGPAMSFFRRKVKGKEQEKTLDVKSTKASVAVHSPQKSTKN-HALLEAAGPSHVAINAISANMDSFSSSRTATLKKQPSHMEAAHFGDLGRSC--------LDYQTQETKSSLSKTLEQVLRDTVVLPYFLQFMELRRMEHLVKFWLEAESFHSTTWSRIRAHSLNTVKQSSLAEPVSPSKRHETPASSVTEALDRRLGDSSSAPLLVTQSEGTDLSSRTQNPQNHLLLSQEGHSARSLHREVARTGSHQIPTDSQDSSSRLAVGSRN-SCSSPLRELSEKLMKSIEQDAVNTFTKYISPDAAKPIPITEAMRNDIIAKICGEDGQ-----VDPNCFVLAQAVVFSAMEQEHFSEFLRSHHFCKYQIEVLTSGTVYLADILFCESALFYFSEYMEKEDAVNILQFWLAADNFQSQLAAKKG-QYDGQEAQNDAMILYDKYFSLQATHPLGFDDVVRLEIESNICREGGPLPNCFTTPLRQAWTTMEKVFLPGFLSSNLYYKYLNDLIHS---VRGDEFLGGNVSLAAHGSVCLPEESHS---------GGSDGSTA--QSSVKKASIKILKNFDEAIIVDAASLDPESLYQRTYAGKMSFGRVSDLGQFIRESEPEPDVKKSK--------GFMFSQAMKKWVQGNTDEAQEELAWKIAKMIVSDVMQQAHHDQPLEKSTKL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O43572-1", "uniprot_id": "AKA10_HUMAN", "id": "O43572-1", "name": "A-kinase anchor protein 10, mitochondrial", "aln": "MRGAGPSPRQSPRTLRPDPGPAMSFFRRKVKGKEQEKTSDVKSIKASISVHSPQKSTKN-HALLEAAGPSHVAINAISANMDSFSSSRTATLKKQPSHMEAAHFGDLGRSC--------LDYQTQETKSSLSKTLEQVLHDTIVLPYFIQFMELRRMEHLVKFWLEAESFHSTTWSRIRAHSLNTVKQSSLAEPVSPSKKHETTASFLTDSLDKRLEDSGSAQLFMTHSEGIDLNNRTNSTQNHLLLSQECDSAHSLRLEMARAGTHQVSMETQESSSTLTVASRN-SPASPLKELSGKLMKSIEQDAVNTFTKYISPDAAKPIPITEAMRNDIIARICGEDGQ-----VDPNCFVLAQSIVFSAMEQEHFSEFLRSHHFCKYQIEVLTSGTVYLADILFCESALFYFSEYMEKEDAVNILQFWLAADNFQSQLAAKKG-QYDGQEAQNDAMILYDKYFSLQATHPLGFDDVVRLEIESNICREGGPLPNCFTTPLRQAWTTMEKVFLPGFLSSNLYYKYLNDLIHS---VRGDEFLGGNVSLTAPGSVGPPDESHP---------GSSDSSAS--QSSVKKASIKILKNFDEAIIVDAASLDPESLYQRTYAGKMTFGRVSDLGQFIRESEPEPDVRKSK--------GSMFSQAMKKWVQGNTDEAQEELAWKIAKMIVSDIMQQAQYDQPLEKSTKL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F1QDF6-1", "uniprot_id": "F1QDF6_DANRE", "id": "F1QDF6-1", "name": "", "aln": "----------------------MSFFRRKAKGKEPERPADAKASKAPVSPHSPSLSGRNHHAILEAAGPSHVAISAISANMDSFARGRTAILKKQPSHMEAAHFGDLGRSS--------VNYQIQETRSRLSKTVDQILRDNVALPYFIQFMETRSAEHLVRFWLEAESFRSTSWSRVRAHSLNSVKHSTLAEPAAALGSPDSPDSPNHSSRPLNLDEGDEEDAFSSRTSSRPHTPSPQDTNSHSGALMSHRDSVSFD-GTAQPGTLQLQPALRSETPTRQTSSRTGTPVKGLRELSDKLMKSIERDAVNIFTKYISPDAARPIPITEQIRNDIVAKICGEDGQ-----VDPNCFVIAQSVVFSIIDQQHFTEFLRSHYFCKYQIEVLTSGSVFLADILFCESALFYFSEYMEKEDAMNVLQFWLAAENFQDQLAAKKG-QYDGQEAQNDAMILYDKYFSLQATNPLGFGDSVRMEIESNICREGGPLPDCFNTPLRQAWTTMEKVYMPGFLSSNLYYKYLSDLINS---VRVDEFIGGNANTPNQGWTQ-EGERNS---------SVTEGSHVQLQQGTKKAAIKILKNFDEAITVDIASLDPESLYQRPYAGRMTFGKVNELGQFIREAEPEPDVKKSK--------GSMFSLAMKKWVQGNSDEAQEEMAWKIAKMIVNDVMQQGHHGSPEVKATKL", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9V3I3-1", "uniprot_id": "Q9V3I3_DROME", "id": "Q9V3I3-1", "name": "", "aln": "----------------------MLNYIKRHASRRRSSQDATDAICGQMPAYDVDTNDVAGAGDAANAHKRHSLRSTTSFCDEVFLEAEEEGGVGTTGGGGGGGGGGGGGGAPSDGISLASNDDIFTYNSRLSMNLASIVNDPNCLSYFVQYLDTRQALPLIKFYLDIENFKRAALTQEKE------------EPEEPPRKAIEQSSPHKDD-----KDVPELKTLCDLSMRKPLTDDEKS---------------------------RIYAETNKQLNRQKSGTDS--------VLNAELSRASISDAIAIYQKYLIVNASLQVELPIVILAHISLLLCGRDKSECSKPIPASCFDEAREFVLEQLERDHVQGFLQSGYYSTYCLELIEGGSVNIYDVLNSELALFYFTEYLEQRQERECLEFWITAINFRKSFACGEEKEEDRKAAQSDAMIIYDKYFSLQSECRLWMSQKLRLRVEQAICAPN-EQWQAFDLALLVTAKYLEQKYFADFLKSHIFDNYVNELKVKRDNSTTHPNLQHTLSLRRAGKSSNGQQQRHRKTLSMSDCTHISQHNTLLASMDQAPSKTALNHQSGNLNIDARQLTNPQLLWQRPVGALKFGFVNSLGRYERDFEAVDAVALKSQPWSLSVSGSKLKNAMRKLVNLPEDNVQEEIAWQVAEMIVRDVTSVTLSGKTPPLA---", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q08760-1", "uniprot_id": "RAX1_YEAST", "id": "Q08760-1", "name": "Bud site selection protein RAX1", "aln": "--------------------------MKEELSKVSSMQNFEMIQRERLPTLYEVLIQRTSQPVDLWTFYTFLSQFPYAINYLDFWVD-------------------------------------LMTHTRLCKNYIELVRKS--LINFPQEQQQNGSTSTATFDLLNALIEEGHLD---------------PEAPDKLLENSGPDVPFSPKLNELLGDWKHQSGIGQEALRN----------------------------------EDVALIVDEIMKRRSQQDGK-------PQITTKQLLHSAVGLCNTYLVSPEQSERYLSNIPMETRNRIIESVQIERKY------DIEIFDDLKNLTYQFLEMDCFPKFLSR-------------------------------VALHNIHDEISDWRFHSVGVTNEKSNRSRGQTHISRSPFSNHTSISRIGFGLLWLGIGFWIGYVLIFLAYS----------RAIRVVTVVPFTLGCYCIVCGMYQVDIVYSWFG--------VTQRLLHRHKNAGNDEGDASSDTDHVP----------------------------MILAVFGGRRRLTRIEHPFTRQLLRKRGLWCLLLVVGATAAFTVIFSCVPGRRV-------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :. .: . :. : . . : * .: *. . .::.. * * * : . * * :. *. : : : : . . :. : . : . :. * : . . * : .. . :: : . ** : .: . .* .. . ... . . . . ...: * : * : :. : : . .: . . . .: . .: .:.. . * : * . : . : : *. . : . ", "identical_positions": 18, "similar_positions": 101, "identity": "2.57%" }, { "cls_id": "homologset.agr.MGI:1890219", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P58365-1", "uniprot_id": "CAD23_RAT", "id": "P58365-1", "name": "Cadherin-23", "aln": "MRHPPVTWCAMLWLLMLVSGSWGQVNRLPFFTNHFFDTYLLISEDTPVGSSVTQLLARDMDNDPLVFGVSGEEASRFFAVEPDTGVVWLRQPLDRETKSEFTVEFSVSDHQGVITRKVNIQVGDVNDNAPTFHNQPYSVRIPENTPVGTPIFIVNATDPDLGAGGSVLYSFQPPSQFFAIDSARGIVTVIRELDYEVTQAYQLTVNATDQDKTRPLSTLANLAIIITDVQDMDPIFINLPYSTNIYEHSPPGTTVRVITAVDQDKGRPRGIGYTIVSGNTNSIFALDYISGALTLNGLLDRENPLYSHGFILTVKGTELNDDRSPSDATVTTTFNILVIDINDNAPEFNSSEYSVAITELAQVGFALPLFIQVVDKDE--GLNSMFEVYLVGNNSHHFIISPTSVQGKADIRIRVAIPLDYETVDRYDFDLFANESVPDHVGYAKVKITLINENDNRPIFSQPLYNVSLYENITVGTSVLTVLATDNDVGTFGEVNYFFSDDPDRFSLDKDTGLIMLIARLDYELIQRFTLTVIARD---GGGEETTGRVRINVLDVNDNVPTFQKDAYVGALRENEPSVTQLVRLRATDEDSPPNNLITYSIVNASAFGSYFDISVYEGYGVISVSRPLDYEQIPNGLIYLTVMAKDAGNPPLYSTVPVTIEVFDENDNPPTFSKPAYFVSVVENIMAGATVLFLNATDLDRSREYGQESIIYSLEGSSQFRINARSGEITTTSLLDRETKAEYILIVRAVDGGVGHNQKTGIATVNVTLLDINDNHPTWKDAPYYINLVEMTPPDSDVTTVVAVDPDLGKNGTLVYSIQPPNKFYSLNSTTGKIRTTHVMLDRENPDPVEAELMRKIIVSVTDCGRPPLKATSSATVFVNLLDLNDNDPTFQNLPFVAEVLEGTPAGVSVYQVVAIDLDEGLNGLVSYRMQVGMPRMDFVINSTSGVVTTTAELDRERIAEYQLRVVASDAGTPTKSSTSTLTIRVLDVNDETPTFFPAVYNVSVSEDVPREFRVVWLNCTDNDVG--LNAELSYFITAGNVDGKFSVGYRDAVVRTVVG----LDRETTAAYTLVLEAIDNVPVGKRRTGTATVFVTVLDVNDNRPIFLQSSYEASVPEDIPEGHSIVQLKATDADEGEFGRVWYRILHGNHGNNFRLHVSSGLLVRGPRPLDRERNSSHVLMAEAYNHDLGPMRSSVRVIVYVEDVNDEAPVFTQQQYNRLGLRETAGIGTSVIVVRATDRDTGDGGLVNYRILSGAEGKFEIDESTGLIVTVDYLDYETKTSYLMNVSATDGAPPFNQGFCSVYVTLLNELDEAVQFSNASYEAVIMENLALGTEIVRVQAYSIDNLNQITYRFDAYTSAQAKALFKIDAITGVITVKGLVDREKGDFYTLTVVADDGGPKVDSTVKVYVTVLDENDNSPRFDFTSDSAISVPEDCPVGQRVATVKARDPDAGSNGQVVFSLASGNIAGAFEIITSNDSIGEVFVAKP---LDREELDHYILKIVASDR--GTPPRKKDHILQVTILDVNDNPPVIESPFGYNVSVNENVGGGTSVVQVRATDRDIGINSVLSYYITEGNEDMTFRMDRISGEIATRPAPPDRERQNFYHLVVTVEDEGTPTLSATTHVYVTIVDENDNAPVFQQPHYEVVLDEGPDTVNTSLITVQALDLDEGPNGTVTYAIVAGNIINTFRINRRTGVITAAKELDYEISHGRYTLIVTATDQCPILSHRLTSTTTVLVNVNDINDNVPTFPRDYEGPFDVTEGQPGPRVWTFLAHDRDSGPNGQVEYSVVDGDPLGEFVISPVEGVLRVRKDVELDRETIAFYNLTICARDRGVPPLSSTMLVGIRVLDINDNDPVLLNLPMNITISENSPVSSFVAHVLASDADSGCNALLTFNITAGNRERAFFINATTGIVTVNRPLDRERIPEYRLTVSVKDNPENPRIARKDFDLLLVSLADENDNHPLFTEGTYQAEVMENSPAGTPLTVLNGPILALDADEDVYAVVTYQLLGTHSDLFVIDNSTGVVTVRSGVIIDREAFSPPFLELLLLAEDVGQLNGTAYLFITILDDNDNWPTFSPPAYTVHLLENCPPGFSVLQITATDEDS--GLNGELVYRIEAGAQDRFLIHPVTGVIRVGNATID--REEQESYRLTVVATDRGTVPLSGTATVTILIDDINDSRPEFLNPIQTVSVLESTEPGTVIANVTAIDLDLNPKLEYHILSIVAKDDTDRLVPDQEDAFAVNINTGSVIVKSPLNRELVATYEVTLSVIDNASDLPERSVSVPNAKLTVNILDVNDNTPQFKPFGITYYTERVLEGATPGTTLIAVAAVDPDKGLNGLITYTLLDLIPPGYVQLEDSSAGKVIANRTVDYEEVHWLNFTVRASDNGSPPRAAEIPVYLEIVDINDNNPIFDQLSYQEAVFEDVAVGTVILRVTATDADSGNFALIEYSLVDGEGKFAINPNTGDIYVLSSLDREKKDHYILTALAKDNPGDVASNRRENSVQVVIRVLDVNDCRPQFSKPQFSTSVYENEPAGTSVITMLATDQDEGSNGQLTYSLEGPGMEAFSVDMDSGLVTTQRPLQSYERFNLTVVATDGGEPPLWGTTMLLVEVIDVNDNRPVFVRPPNGTILHIKEEIPLRSNVYEVYATDKDEGLNGAVRYSFLKSTGNRDWEYFTIDPISGLIQTAQRLDREKQAVYSLILVASDLGQPVPYETMQPLQVALEDIDDNEPLFVRPPKGSPQYQLLTVPEHSPRGTLVGNVTGAVDADEGPNAIVYYFIAAGNEDKNFHLQPDGRLLVLRDLDRETEAIFSFIVKASSNRSWTPPRGPSPALDLLTDLTLQEVRVVLEDINDQPPRFTKAEYTAGVATDAKVGSELIQVLALDADIGNNSLVFYGILAIHYFRALANDSEDVGQVFTMGSVDGILRTFDLFMAYSPGYFVVDIVARDLAGHNDTAIIGIYILRDDQRVKIVINEIPDRVRGFEEEFIRLLSNITGAIVNTDDVQFHVDMKGRVNFAQTELLIHVVNRDTNRILDVDRVIQMIDENKEQLRNLFRNYNVLDVQPAISVQLPDDMSALQMAIIVLAILLFLAAMLFVLMNWYYRTIHKRKLKAIVAGSAGNRGFIDIMDMPNTNKYSFDGANPVWLDPFCRNLELAAQAEHEDDLPENLSEIADLWNSPTRTHGTFGREPAAVKPEDDRYLRAAIQEYDNIAKLGQIIREGPIK-----------------------------------LIHTDLEEEPGDHSPGQGSLRFRHKPPTELKGPDGIHIVHGSTGTLLATDLNSLPEDDQKGLDRSLETLTASEATAFERNARTESAKSTPLHKLRDVIMESPLEITEL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q99PF4-1", "uniprot_id": "CAD23_MOUSE", "id": "Q99PF4-1", "name": "Cadherin-23", "aln": "MRYSLVTCYAVLWLLMLVPGSWGQVNRLPFFTNHFFDTYLLISEDTPVGSSVTQLLARDMDNDPLVFGVSGEEASRFFAVEPDTGVVWLRQPLDRETKSEFTVEFSVSDHQGVITRKVNIQVGDVNDNAPTFHNQPYSVRIPENTPVGTPIFIVNATDPDLGAGGSVLYSFQPPSPFFAIDSARGIVTVIQELDYEVTQAYQLTVNATDQDKTRPLSTLANLAIIITDMQDMDPIFINLPYSTNIYEHSPPGTTVRVITAVDQDKGRPRGIGYTIVSGNTNSIFALDYISGALTLNGLLDRENPLYSHGFILTVKGTELNDDRTPSDATVTTTFNILVIDINDNAPEFNSSEYSVAITELAQVGFALPLFIQVVDKDEDLGLNSMFEVYLVGNNSHHFIISPTSVQGKADIRIRVAIPLDYETVDRYDFDLFANESVPDHVGYAKVKITLINENDNRPIFSQPLYNVSLYENITVGTSVLTVLATDNDVGTFGEVNYFFSDDPDRFSLDKDTGLIMLIARLDYELIQRFTLTVIARD---GGGEETTGRVRINVLDVNDNVPTFQKDAYVGALRENEPSVTQLVRLRATDEDSPPNNLITYSIVNASAFGSYFDISIYEGYGVISVSRPLDYEQIPNGLIYLTVMAKDAGNPPLYSTVPVTIEVFDENDNPPTFSKPAYFVSVLENIMAGATVLFLNATDLDRSREYGQESIIYSLEGSSQFRINARSGEITTTSLLDRETKSEYILIVRAVDGGVGHNQKTGIATVNVTLLDINDNHPTWKDAPYYINLVEMTPPDSDVTTVVAVDPDLGENGTLVYSIHPPNKFYSLNSTTGKIRTTHVMLDRENPDPVEAELMRKIIVSVTDCGRPPLKATSSATVFVNLLDLNDNDPTFRNLPFVAEILEGTPAGVSVYQVVAIDLDEGLNGLVSYRMQVGMPRMDFVINSTSGVVTTTAELDRERIAEYQLRVVASDAGTPTKSSTSTLTVRVLDVNDETPTFFPAVYNVSVSEDVPREFRVVWLNCTDNDVG--LNAELSYFITAGNVDGKFSVGYRDAVVRTVVG----LDRETTAAYTLVLEAIDNGPVGKRRTGTATVFVTVLDVNDNRPIFLQSSYEASVPEDIPEGHSIVQLKATDADEGEFGRVWYRILHGNHGNNFRIHVGSGLLMRGPRPLDRERNSSHVLMVEAYNHDLGPMRSSVRVIVYVEDVNDEAPVFTQQQYNRLGLRETAGIGTSVIVVRATDKDTGDGGLVNYRILSGAEGKFEIDESTGLIVTVDYLDYETKTSYLMNVSATDGAPPFNQGFCSVYVTLLNELDEAVQFSNASYEAVIMENLALGTEIVRVQAYSIDNLNQITYRFDAYTSAQAKALFKIDAITGVITVKGLVDREKGDFYTLTVVADDGGPKVDSTVKVYITVLDENDNSPRFDFTSDSAISVPEDCPVGQRVATVKARDPDAGSNGQVVFSLASGNIAGAFEIITSNDSIGEVFVAKP---LDREELDHYILKVVASDR--GTPPRKKDHILQVTILDVNDNPPVIESPFGYNVSVNENVGGGTSVVQVRATDRDIGINSVLSYYITEGNEDMTFRMDRISGEIATRPAPPDRERQNFYHLVVTVEDEGTPTLSATTHVYVTIVDENDNAPVFQQPHYEVVLDEGPDTINTSLITVQALDLDEGPNGTVTYAIVAGNIINTFRINKHTGVITAAKELDYEISHGRYTLIVTATDQCPILSHRLTSTTTVLVNVNDINDNVPTFPRDYEGPFDVTEGQPGPRVWTFLAHDRDSGPNGQVEYSVVDGDPLGEFVISPVEGVLRVRKDVELDRETIAFYNLTICARDRGVPPLSSTMLVGIRVLDINDNDPVLLNLPMNVTISENSPVSSFVAHVLASDADSGCNALLTFNITAGNRERAFFINATTGIVTVNRPLDRERIPEYRLTVSVKDNPENPRIARKDFDLLLVSLADENDNHPLFTEGTYQAEVMENSPAGTPLTVLNGPILALDADEDVYAVVTYQLLGTHSDLFVIDNSTGVVTVRSGIIIDREAFSPPFLELLLLAEDIGQLNGTAHLFITILDDNDNWPTFSPPTYTVHLLENCPPGFSVLQVTATDEDS--GLNGELVYRIEAGAQDRFLIHPVTGVIRVGNATID--REEQESYRLTVVATDRGTVPLSGTAIVTILIDDINDSRPEFLNPIQTVSVLESAEPGTIIANVTAIDLDLNPKLEYHIISIVAKDDTDRLVPDQEDAFAVNINTGSVMVKSPLNRELVATYEVTLSVIDNASDLPEHSVSVPNAKLTVNILDVNDNTPQFKPFGITYYTERVLEGATPGTTLIAVAAVDPDKGLNGLITYTLLDLTPPGYVQLEDSSAGKVIANRTVDYEEVHWLNFTVRASDNGSPPRAAEIPVYLEIVDINDNNPIFDQPSYQEAVFEDIAVGTVILRVTATDADSGNFALIEYSLVDGEGKFAINPNTGDISVLSSLDREKKDHYILTALAKDNPGDVASNRRENSVQVVIRVLDVNDCRPQFSKPQFSTSVYENEPAGTSVITMLATDQDEGSNSQLTYSLEGPGMEAFSVDMDSGLVTTQRPLQSYERFNLTVVATDGGEPPLWGTTMLLVEVIDVNDNRPVFVRPPNGTILHIKEEIPLRSNVYEVYATDNDEGLNGAVRYSFLKTTGNRDWEYFTIDPISGLIQTAQRLDREKQAVYSLILVASDLGQPVPYETMQPLQVALEDIDDNEPLFVRPPKGSPQYQLLTVPEHSPRGTLVGNVTGAVDADEGPNAIVYYFIAAGDEDKNFHLQPDGRLLVLRDLDRETEATFSFIVKASSNRSWTPPRGPSPALDLLTDLTLQEVRVVLEDINDQPPRFTKAEYTAGVATDAKVGSELIQVLALDADIGNNSLVFYGILAIHYFRALANDSEDVGQVFTMGSVDGILRTFDLFMAYSPGYFVVDIVARDLAGHNDTAIIGIYILRDDQRVKIVINEIPDRVRGFEEEFIRLLSNITGAIVNTDDVQFHVDMKGRVNFAQTELLIHVVNRDTNRILDVDRVIQMIDENKEQLRNLFRNYNVLDVQPAISVQLPDDMSALQMAIIVLAILLFLAAMLFVLMNWYYRTIHKRKLKAIVAGSAGNRGFIDIMDMPNTNKYSFDGSNPVWLDPFCRNLELAAQAEHEDDLPENLSEIADLWNSPTRTHGTFGREPAAVKPDDDRYLRAAIQEYDNIAKLGQIIREGPIKGSLLKVVLEDYLRLKKLFAQRMVQKASSCHSSISELIHTDLEEEPGDHSPGQGSLRFRHKPPMELKGQDGIHMVHGSTGTLLATDLNSLPEDDQKGLDRSLETLTASEATAFERNARTESAKSTPLHKLRDVIMESPLEITEL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9H251-1", "uniprot_id": "CAD23_HUMAN", "id": "Q9H251-1", "name": "Cadherin-23", "aln": "MGRHVATSCHVAWLLVLISGCWGQVNRLPFFTNHFFDTYLLISEDTPVGSSVTQLLAQDMDNDPLVFGVSGEEASRFFAVEPDTGVVWLRQPLDRETKSEFTVEFSVSDHQGVITRKVNIQVGDVNDNAPTFHNQPYSVRIPENTPVGTPIFIVNATDPDLGAGGSVLYSFQPPSQFFAIDSARGIVTVIRELDYETTQAYQLTVNATDQDKTRPLSTLANLAIIITDVQDMDPIFINLPYSTNIYEHSPPGTTVRIITAIDQDKGRPRGIGYTIVSGNTNSIFALDYISGVLTLNGLLDRENPLYSHGFILTVKGTELNDDRTPSDATVTTTFNILVIDINDNAPEFNSSEYSVAITELAQVGFALPLFIQVVDKDENLGLNSMFEVYLVGNNSHHFIISPTSVQGKADIRIRVAIPLDYETVDRYDFDLFANESVPDHVGYAKVKITLINENDNRPIFSQPLYNISLYENVTVGTSVLTVLATDNDAGTFGEVSYFFSDDPDRFSLDKDTGLIMLIARLDYELIQRFTLTIIARD---GGGEETTGRVRINVLDVNDNVPTFQKDAYVGALRENEPSVTQLVRLRATDEDSPPNNQITYSIVSASAFGSYFDISLYEGYGVISVSRPLDYEQISNGLIYLTVMAMDAGNPPLNSTVPVTIEVFDENDNPPTFSKPAYFVSVVENIMAGATVLFLNATDLDRSREYGQESIIYSLEGSTQFRINARSGEITTTSLLDRETKSEYILIVRAVDGGVGHNQKTGIATVNITLLDINDNHPTWKDAPYYINLVEMTPPDSDVTTVVAVDPDLGENGTLVYSIQPPNKFYSLNSTTGKIRTTHAMLDRENPDPHEAELMRKIVVSVTDCGRPPLKATSSATVFVNLLDLNDNDPTFQNLPFVAEVLEGIPAGVSIYQVVAIDLDEGLNGLVSYRMPVGMPRMDFLINSSSGVVVTTTELDRERIAEYQLRVVASDAGTPTKSSTSTLTIHVLDVNDETPTFFPAVYNVSVSEDVPREFRVVWLNCTDNDVG--LNAELSYFITGGNVDGKFSVGYRDAVVRTVVG----LDRETTAAYMLILEAIDNGPVGKRHTGTATVFVTVLDVNDNRPIFLQSSYEASVPEDIPEGHSILQLKATDADEGEFGRVWYRILHGNHGNNFRIHVSNGLLMRGPRPLDRERNSSHVLIVEAYNHDLGPMRSSVRVIVYVEDINDEAPVFTQQQYSRLGLRETAGIGTSVIVVQATDRDSGDGGLVNYRILSGAEGKFEIDESTGLIITVNYLDYETKTSYMMNVSATDQAPPFNQGFCSVYITLLNELDEAVQFSNASYEAAILENLALGTEIVRVQAYSIDNLNQITYRFNAYTSTQAKALFKIDAITGVITVQGLVDREKGDFYTLTVVADDGGPKVDSTVKVYITVLDENDNSPRFDFTSDSAVSIPEDCPVGQRVATVKAWDPDAGSNGQVVFSLASGNIAGAFEIVTTNDSIGEVFVARP---LDREELDHYILQVVASDR--GTPPRKKDHILQVTILDINDNPPVIESPFGYNVSVNENVGGGTAVVQVRATDRDIGINSVLSYYITEGNKDMAFRMDRISGEIATRPAPPDRERQSFYHLVATVEDEGTPTLSATTHVYVTIVDENDNAPMFQQPHYEVLLDEGPDTLNTSLITIQALDLDEGPNGTVTYAIVAGNIVNTFRIDRHMGVITAAKELDYEISHGRYTLIVTATDQCPILSHRLTSTTTVLVNVNDINDNVPTFPRDYEGPFEVTEGQPGPRVWTFLAHDRDSGPNGQVEYSIMDGDPLGEFVISPVEGVLRVRKDVELDRETIAFYNLTICARDRGMPPLSSTMLVGIRVLDINDNDPVLLNLPMNITISENSPVSSFVAHVLASDADSGCNARLTFNITAGNRERAFFINATTGIVTVNRPLDRERIPEYKLTISVKDNPENPRIARRDYDLLLIFLSDENDNHPLFTKSTYQAEVMENSPAGTPLTVLNGPILALDADQDIYAVVTYQLLGAQSGLFDINSSTGVVTVRSGVIIDREAFSPPILELLLLAEDIGLLNSTAHLLITILDDNDNRPTFSPATLTVHLLENCPPGFSVLQVTATDEDS--GLNGELVYRIEAGAQDRFLIHLVTGVIRVGNATID--REEQESYRLTVVATDRGTVPLSGTAIVTILIDDINDSRPEFLNPIQTVSVLESAEPGTVIANITAIDHDLNPKLEYHIVGIVAKDDTDRLVPNQEDAFAVNINTGSVMVKSPMNRELVATYEVTLSVIDNASDLPERSVSVPNAKLTVNVLDVNDNTPQFKPFGITYYMERILEGATPGTTLIAVAAVDPDKGLNGLVTYTLLDLVPPGYVQLEDSSAGKVIANRTVDYEEVHWLNFTVRASDNGSPPRAAEIPVYLEIVDINDNNPIFDQPSYQEAVFEDVPVGTIILTVTATDADSGNFALIEYSLGDGESKFAINPTTGDIYVLSSLDREKKDHYILTALAKDNPGDVASNRRENSVQVVIQVLDVNDCRPQFSKPQFSTSVYENEPAGTSVITMMATDQDEGPNGELTYSLEGPGVEAFHVDMDSGLVTTQRPLQSYEKFSLTVVATDGGEPPLWGTTMLLVEVIDVNDNRPVFVRPPNGTILHIREEIPLRSNVYEVYATDKDEGLNGAVRYSFLKTAGNRDWEFFIIDPISGLIQTAQRLDRESQAVYSLILVASDLGQPVPYETMQPLQVALEDIDDNEPLFVRPPKGSPQYQLLTVPEHSPRGTLVGNVTGAVDADEGPNAIVYYFIAAGNEEKNFHLQPDGCLLVLRDLDREREAIFSFIVKASSNRSWTPPRGPSPTLDLVADLTLQEVRVVLEDINDQPPRFTKAEYTAGVATDAKVGSELIQVLALDADIGNNSLVFYSILAIHYFRALANDSEDVGQVFTMGSMDGILRTFDLFMAYSPGYFVVDIVARDLAGHNDTAIIGIYILRDDQRVKIVINEIPDRVRGFEEEFIHLLSNITGAIVNTDNVQFHVDKKGRVNFAQTELLIHVVNRDTNRILDVDRVIQMIDENKEQLRNLFRNYNVLDVQPAISVRLPDDMSALQMAIIVLAILLFLAAMLFVLMNWYYRTVHKRKLKAIVAGSAGNRGFIDIMDMPNTNKYSFDGANPVWLDPFCRNLELAAQAEHEDDLPENLSEIADLWNSPTRTHGTFGREPAAVKPDDDRYLRAAIQEYDNIAKLGQIIREGPIKGSLLKVVLEDYLRLKKLFAQRMVQKASSCHSSISELIQTELDEEPGDHSPGQGSLRFRHKPPVELKGPDGIHVVHGSTGTLLATDLNSLPEEDQKGLGRSLETLTAAEATAFERNARTESAKSTPLHKLRDVIMETPLEITEL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VFH5-1", "uniprot_id": "Q9VFH5_DROME", "id": "Q9VFH5-1", "name": "", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MHNESQPPANGNGIDSMDYKKVRLKGQRRRSFSSYISSISIQVIILTTLIS---------------------------------------------------------------------------------------------------------------------------------------LVASNRPPRFAIDGQSEIVLRLKESPETKVGTLIYTLKGYD-------------PDNDPLTFGKRNSHDSEIIRIENTGGNEAKIFLAKELDRELQDEYAIVLTLTDSHYSDHNYVTQSFLLLVEDINDNVPTFLPYQNAIEIPEG-SAPGVVSTLEATDADEGAYGQVVYYLQELDGDNDVFSIATHQGKGILRLQKELDYERKSLYQLRVLAIDRANQGPINTGTAAILVKVKDLEDQPPEFVEVQAVARIAEDAPVGTKVLRVRAIDGDRGINN---PIAYSLEANDLFDINPHTGIVHTLTKLDREEQSDQVNGAHILR---------------------------------------------------------------ISATELSKSNTQMAPTTVRTEVTVIVSDVNDEIPTFGETVYRCEVNENAQTNTPLNFIDEEVQNVVFDHDEGNNGTFR------------------------LFLDPPNDLFEIVPELAVNEANFMLR-----VKNSKSLDFEQFTEVNFTIFAREVDEPSRWSSAHVQIFIRDQNDNFPEFSQTIYNASVLENSEQDTIITHVQAVDVDSGDYGTMGIRYTNLRGGIAHLLNLNPITGVITIKQAGGTAFDREIISRHYLTVEAIDNAGQGNR--NTAQIIVDILDVNDNAPTFPQRQYETKLLENQAEFETPLQLEARDAD-----------LNGTENSQVTYEIVEGLYRSN---------------------------------------------------------------------------------------------FTIDPQSGLLRPVHSFDFEELVDGSSRRSDPYTGGSFSIREIDLLVRAR---------------------------------------------------------------------------------------DSGIPMLSTVVPVLIYVQDVNDNAPIFQQS-FYAKTVPEDLPGGSSVLQVTAIDRDGSAPNNVVVYRIQTGAGDKFIINSETGVISVAHGANLDPDLTESKRSLYTLSVIALDGGLGNSQLMTTCTVNISIQDVNNKPPVLKEMPALQILENTPVGTLVYRIQATDLDHKAILRYKLNPEHCEG--------------------------------------------------------RTEEGALVKSSEYDFLGAFEVDSIEGTLKVVKLLDRE----------------------------------------RVEHIKLAITVEDLAAAKGRQIAEGFLSIQVLDENDNNPKFRLPFYRQSITENSINGAMIVNVLASDVD---KNRTITYALEGNPTYRSLMHLDPQTGEIVVASKIDHEQHQWLNFSVRATDSGIPARSSLVDVYITVLDENDNNPYFVGGSKNYTISENAAPGTRVATLQAGDADSGDFGKITFLMDRISSQGKFTIDADTGVLTVADRLDRESKDSYNLVIEAWDNYQFGFLAGESR-----------------------------------------------------------------------------------------------------------NAFKQVFISILDENDNPPEVDLPMSCVLITEYHELHERVASIVGKDADDPTTPNGRLDFAITRGNKDGMFELRQIDAWNAQIFASKSLRNRYGNYSLTITTRDMGLPANIVHNTLDICVSDFNDHAPVFVRPLHNT------------------------------------------------------------------------------------------------------------------------TVRIPENATVGTLILQAYASDGDMGQNALVRYRLKPDPLGSYKMFEVDGS------------------------------------------------------------------------------------------------------TGELFLKEQLNREKQKIHEIRIEAYDQG---LPTSLSSDLDLTIYVRNVNDYEPQFMVNEISVNFTEHSDPGSERIKLPDTIDKD--------------------------------------------------------------------------------------------------QLELDDPNDTPSQVCYFIVNGN-EAGYFRLDPETHILTVDRELDR--------------------------------EVIANFTLYVRATENCRNDSISGGEKRRRMGIEINNRLGGIVHN---------------QQFGYDRFKHSRQLRSTESNEYGPEDAELLSYEAYDSSQEDPTGGLATTHPELDSTVIKVKVRVLDINDNPPRFRSKIFTGGITTNADFGLKFMRVEATDADEGDNGRIGYYQVGEIRQTLSEGLENVRKAPFLLDQETGEVQLNFDPQKGMKGYFDFVVLANDTSGMKDVAHVFIYLLREDQKVRFVFRLQPDELRSRVDSFRDTLSNITESIVNIDEIKVHENKDGSVDKTKTDLYMHLVEREDNSIYEVSEVLKLIDSHIESLNGLFKELNVLDTQAAEAQLLTAGPSRGPLFVWLIFTNLFLATLLVVTIALCASQRNGYRRQLRAAKVNIFRGHS--------------------------SMSLQDAQEPATRVPN------------TNKHSVQGSNPIWLKGYDNEWFKSEESGS------------------------------------------------------------------------------------------IGGHDSLDDNFLAVATQDMHETLKGTAKLFNNSNDLNRHFNLYNQIDKMT----NNAQILARKLETTEL", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :::.* * :. . * ::* .* * :* .*. .** * .* *.*.: * .. .: :*.* ::. .. .. :*.:. *: .*** ***: . . *: . . : . *:* .** ** :.:::.: * .. : .* . : * *:******* . : *. .: : *.*** *. . . :.* : . .. .. *.*: ::* *:: :.: ****: . : : .: .* .*..: ::* * :*:** * : .. : *: .*:.** :.* * **. : .* ****.. * **.::* : * : **** ::: : .: : : : . .:. .: .** : ..* : * :: * .* : : *. . ..**: .. . * : . :.*: **: : : *.*.. :.: . :*::. * .: .** *:::* :: :.* :.. *:: *:: : : : * **: * * ::**.** *: :: :. ::..* * * . : * *.: :.:. .*: . :*** : : * :***** *:* .** ::* :****** * * * .**:.: *: .* .: :**:* *** *:*....:. .: .** . * ** .:**: .*. :*:* .. . * . . .*. .: : *.* * :.:.* * : * * ***:* *: : * ::*** * *. * *.* * *..: .:**. . . .. * * : .. *. .. *. * ..: . * *.::* * *.. . ::::* *:*::***::. . :: * ** . :*. *:. :. *. ** ..::..:.:...*:.: *::: :* .:: ** : : .: :. :.:: . . * : : ::* * *** *.* : . :. *. : ..** * * :.:. ::*:* . :: . .: ::*:* : *::: * * *:*. ** : * * *** ***:* ::. . * *****:. .: ** : *.***** . :** : . : * *:* **::** **** .*.*.:.. ** : :* .. *. ::*:***:*** * .. . * : * * .:...* *. **.* : * * :* :: .. .. : . *:. .* **:.: * * . : * :.*:** * *:.*::.. *: *.** ** :: . * * * * *.*: * * .* :* ..: **:: : ..*:***:. : : * *: .. ...:::.* * :*** .*** ::*... *:. .*:. *.: * :.: : *: : . : .:: ** : :* :** : :: . :.*** :: * .*:**..:.. : .: :: * :.* *.: : :: .:. .. * : :. .:: : : * * * .: . * *: :*:* : ****:**** . :*.*::*:*..* ::::* * *** *:*. : * :. . .: * :.. * :: *** . ::*.* :* :*.* : **:**:**:*::*:. **.:*. :.* ***** :*** *:::.* : .* *: ::*:* :*:*:*: * * :*..*:::**.: *.*..**:: ****.*.* : *. . * : : :: ****::*.* : : : : .* **. .:.* * :*: *..*.. * :* :* *:.:::: . *. .:* . * .:: :: * : : :. :: . * .: * * . *: ** ***", "identical_positions": 497, "similar_positions": 706, "identity": "14.74%" }, { "cls_id": "homologset.agr.MGI:1890220", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9Z282-1", "uniprot_id": "GP132_MOUSE", "id": "Q9Z282-1", "name": "Probable G protein-coupled receptor 132", "aln": "--------------------------MRSEPTNAAGNTTLGVTSVLQSTSVPSSETCH-VSYEESRVVLVVVYSAVCLLGLPANCLTAWLTLLQVLQRNVLAVYLFCLSLCELLYISTVPLWIIYIQNQHKWNLGPQACKVTAYIFFCNIYISILLLCCISCDRYMAVVYALESRGHRHQRTAVTISACVILLVGLVNYPVFDMKV------EKSFCFEPLRMNSKIAGYHYLRFTFGFAIPLGILAFTNHQIFRSIKLSDSLSAAQKNKVKRSAIAVVTIFLVCFAPYHVVLLVKAASFSFYQGDMDAVCAFESRLYTVSMVFLCLSTVNSVADPIIYVLGTDHSRQEVSRIHTGWKKWSTKTYVT---CSKDSEETHLPTELSNTYTFPNPAHPPGSQPAKLGLLCSPERLPEELC", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8I6AM45-1", "uniprot_id": "A0A8I6AM45_RAT", "id": "A0A8I6AM45-1", "name": "", "aln": "MTCFLVILSCQSHLHKGVHRTHIGATMRSEPTNATGNATA-VTSTLQTTSVPTS--CHTLSYEESRVVLVAVYSVVCMLGLPANCLTAWLTLLQVLQRNVLAVYLFCLSLCELLYISTMPLWIIYIQNQHKWSLGQQACKVTAYIFFCNIYTSILLLCCISCDRYMAVVYALESRGHRHQRTAVTISACVVILVGLVNYPVFDMKV------EDSFCFEPLGIDSRIAGYYYLRFTFGFAVPLGVLAFTNHQIFRSIKLSDSLSAAQKNKVKRSAIAVVTIFLVCFAPYHVVLLIKAASFSFYEGDRDAVCDFENRLYTVSTVFLCLSTVNSVADPIIYVLATDHSRQEVCRIHTGWKKWSTKTDVT---YLKDSEETHSPTALMNAYTFPSTVHLPGSQPVELGSLGSAGETA----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9UNW8-1", "uniprot_id": "GP132_HUMAN", "id": "Q9UNW8-1", "name": "Probable G protein-coupled receptor 132", "aln": "-----------------------MCPMLLK-NGYNGNATPVTTTAPWASLGLSAKTCNNVSFEESRIVLVVVYSAVCTLGVPANCLTAWLALLQVLQGNVLAVYLLCLALCELLYTGTLPLWVIYIRNQHRWTLGLLACKVTAYIFFCNIYVSILFLCCISCDRFVAVVYALESRGRRRRRTAILISACIFILVGIVHYPVFQTE-------DKETCFDMLQMDSRIAGYYYARFTVGFAIPLSIIAFTNHRIFRSIKQSMGLSAAQKAKVKHSAIAVVVIFLVCFAPYHLVLLVKAAAFSYYRGDRNAMCGLEERLYTASVVFLCLSTVNGVADPIIYVLATDHSRQEVSRIHKGWKEWSMKTDVTRLTHSRDTEELQSPVALADHYTFSRPVHPPGSP-------CPAKRLIEESC", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A0R4IEK2-1", "uniprot_id": "A0A0R4IEK2_DANRE", "id": "A0A0R4IEK2-1", "name": "", "aln": "-----------------------MVSGRVLTTFRDMMHATTVAQSIMTSMNQSSRASCEISHEADRIPLMVLYIVVFIIGLPANLATVYLTLHQVCRKNVLGIYLLSLSICDLTYLFTLPMWTVYVSRNHEWPWSSLACKITGFVFFNNMYISIFLLCCVSIDRYVAVVYAIESRGLRQKRIAAFVSFLIFIVVGLGHSPVFIMREGQVEEGS-HRCFEPSQSTTLVTGFNYARVCIGFCIPLAILIFTNRAILANVQASTGLQPHQKVKVRYLAVAVVALFLICFAPYHIILLMRAVIFHFPN--LQGKCHFEQHIYTPYKISLGLSTFNSAINPILYVLSSNNIRQEIRRGITSVCDRVLSSQRST---HSSQHNMHSSRSNSEPFPIKGGQMRTVCPTA----------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8M9PLR3-1", "uniprot_id": "A0A8M9PLR3_DANRE", "id": "A0A8M9PLR3-1", "name": "", "aln": "------------------------------------MNVT----SLPTARSNHTSSCGPLYDEENPLPLVALYSTVLTVGLPANLITVFLTFLEVCRKNVLGVYLFSLTLCDLMYLSTLPLWAIYIHRGHRWEWGSLACKITGYVFFNNMYISIFLMCCVSVDRFVAVVYAVESRGLRRMRHAAIISVTIVAVVAIGHVPVFTMTEGNSEKISEKRCFEPSNPSSVVTGLNYARFFVGFFIPLCILTLTNFAILVNVQASAGLMTKTKVKVRNLAVAVVLFFLVCFTPYHVILLLRAVNFHVS----DGKCDFERHVYTPYTISLGLSTVNSALNPVFYVLASSSAQKKIYKG--------LQGLRS------------SSRSSSLA-------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . :: : . : * . : *:.:* .* :*:*** *.:*:: :* : ***.:**:.*::*:* * *:*:* :*: . *.* . ***:*.::** *:* **:::**:* **::*****:**** *: * * :* :. :*.: : *** . **: : ::* * *. .** :** :: :** *: .:: * .* . * **: *:*** :**:**:***::**::*. * :. * :* ::** : * ***.*.. :*::***.:. :::: : . : . ", "identical_positions": 103, "similar_positions": 104, "identity": "24.64%" }, { "cls_id": "homologset.agr.MGI:1890221", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9QX79-1", "uniprot_id": "FETUB_RAT", "id": "Q9QX79-1", "name": "Fetuin-B", "aln": "MGVLRLLVLCTLAACCVARSPPAPPLPNAPFAPLRPLGCNDSEVLAVAGFALQNINRVQKDGYMLTLNRVHDARVHRQEDMGSLFYLMLDVLETGCHVLSRKALKDCGPRIFYETVHGQCKAMFHVNKPRRVLYLPAYNCTLRPVSKRKIHSMCPDCPH--PVDLSAPSVLEAATESLAKFNSENPSKQYALVKVTKATTQWVVGPSYFVEYLIKESPCTQSQDS-CSLQASDSEPVGLCQGSLIKS--PGVP-PQRFKKTVTVSCEFFESQDQVPGGENPADTQDAKKLP------QKNTAPTSSPSITAPRGSIQHLPEQ--EEPEDSKGKSPEEPFPVQLDLTTNPQGDTLDVSFLYLEPEEKKLVVLPFPGKEQRSPECPGPEKQRTP-----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9QXC1-1", "uniprot_id": "FETUB_MOUSE", "id": "Q9QXC1-1", "name": "Fetuin-B", "aln": "MGLLRLLVLCTLAACCMARSPPAPPLPQRPLSPLHPLGCNDSEVLAVAGFALQNINRDQKDGYMLSLNRVHDVREHYQEDMGSLFYLTLDVLETDCHVLSRKAQKDCKPRMFYESVYGQCKAMFHINKPRRVLYLPAYNCTLRPVSKRKTHTTCPDCPS--PIDLSNPSALEAATESLAKFNSKSPSKKYELVKVTKAMNQWVSGPAYYVEYLIKEAPCTKSQAS-CSLQHSDSEPVGICQGSTVQSSLRHVPLIQPVEKSVTVTCEFFESQAQVPGDENPAVTQGPQKLP------QKNTAPTSSPSVTAPRGSIQHLPELDDEKPEESKGGSPEEAFPVQLDLTTNPQGDTLDVSFLYLEPGDKKLVVLPFPGKEQRSAECPGPEKENNPLVLPP", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9UGM5-1", "uniprot_id": "FETUB_HUMAN", "id": "Q9UGM5-1", "name": "Fetuin-B", "aln": "MGLLLPLALCILVLCCGAMSPPQLALNP---SALLSRGCNDSDVLAVAGFALRDINKDRKDGYVLRLNRVNDAQEYRRGGLGSLFYLTLDVLETDCHVLRKKAWQDCGMRIFFESVYGQCKAIFYMNNPSRVLYLAAYNCTLRPVSKKKIYMTCPDCPSSIPTDSSNHQVLEAATESLAKYNNENTSKQYSLFKVTRASSQWVVGPSYFVEYLIKESPCTKSQASSCSLQSSDSVPVGLCKGSLTRT---------HWEKFVSVTCDFFESQAPATGSENSAVNQKPTNLPKVEESQQKNTPPTDSPSKAGPRGSVQYLPDLD---DKNSQEKGPQEAFPVHLDLTTNPQGETLDISFLFLEPMEEKLVVLPFPKEKARTAECPGPAQNASPLVLPP", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "**:* *.** *. ** * *** .* :.* . *****:*********::**: :****:* ****:*.: : : .:****** ******.**** :** :** *:*:*:*:*****:*::*:* *****.***********:* : ***** * * * ..**********:*.:..**:* *.***:* .*** **:*:*******:***:** * **** *** ***:*:** :: :* *:*:*:***** ..*.**.* .* . :** ****.**.*** :.****:*:**: ::*: .*:*.***:*********:***:***:*** ::******** :: *:.***** :: .* ", "identical_positions": 220, "similar_positions": 90, "identity": "55.42%" }, { "cls_id": "homologset.agr.MGI:1890222", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D4AE48-1", "uniprot_id": "MIDN_RAT", "id": "D4AE48-1", "name": "Midnolin", "aln": "-----------MEPQPGGARSCRRGAPGGACELSTT--------------------------AESAAPMSLAIHSTTGTRYDLSVPHDETVEGLRKRLSQRLKVPKERLALLHKDTRLSSGKLQEFGVGDGSKLTLVPTVEAGLMSQASRPEQSVMQALESLTETQPPATPGPGRAAGGGFRKYRLILFKRPWHRQGPQSPERGGERPQVSDFLSGRSPLTLALRVGDHMMFVQLQLAAQHAP---------------------------------------------LQHRHVLAAAAA---------AAAAARGDSSIAT-----------------------------------------------------------------------------------------------------------------------------------------------------------------------PVSSPCRP----VSSAARVPPVSSSPSS--------------PVSPSP---------------------------------------------------------------------------------------------------------------------------------------------------VTAGTFQSHAASTTCPEQTDCSPP------------------------------------------------------------------------------------ASS------NTTSTPGSS--PTPRSRKPGAVIESFVNHAPGVFSGTFSGTLHPNCQDSSGRPRRDIGTILQILNDLLSATRHYQG--------------------------------------------------------MPASLTQLRCHAQCS-PASPAP----------DLTPKTTSCEKLATP---SLLQGQS-----------QIRMCKPPGDRLR---------QTENRATRCKVERLQLLLQQKRLRRKARRDARGPYHWTPSRKAGR---------------------------------------------------SDSSSSGGGGSPSEATGLGLDFEDSVWKPEVNPDIQSEFVVA------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q3TPJ7-1", "uniprot_id": "MIDN_MOUSE", "id": "Q3TPJ7-1", "name": "Midnolin", "aln": "-----------MEPQPGGARSCRRGAPGGACELNTA--------------------------TESAAPMSLAIHSTTGTRYDLSVPHDETVEGLRKRLSQRLKVPKERLALLHKDTRLSSGKLQEFGVGDGSKLTLVPTVEAGLMSQASRPEQSVMQALESLTETQ-------------------------------------------VSDFLSGRSPLTLALRVGDHMMFVQLQLAAQHAP---------------------------------------------LQHRHVLAAAAA---------AAAAARGDSSVAT-----------------------------------------------------------------------------------------------------------------------------------------------------------------------PVSSPCRP----VSSAARVPPVSSSPSS--------------PVSPSP---------------------------------------------------------------------------------------------------------------------------------------------------VTAGSFRSHAASTTCPEQMDCSPP------------------------------------------------------------------------------------ASS------SSTSTPGSS--PTPRSRKPGAVIESFVNHAPGVFSGTFSGTLHPNCQDSSGRPRRDIGTILQILNDLLSATRHYQG--------------------------------------------------------MPPSLTQLRCHAQCS-PASPAP----------DLTPKTTSCEKLAATSSTSLLQGQS-----------QIRMCKPPGDRLR---------QTENRATRCKVERLQLLLQQKRLRRKARRDARGPYHWTPSRKAGR---------------------------------------------------SDSSSSGGGGGPSEATGLGLDFEDSVWKPEVNPDIQSEFVVA------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q504T8-1", "uniprot_id": "MIDN_HUMAN", "id": "Q504T8-1", "name": "Midnolin", "aln": "-----------MEPQPGGARSCRRGAPGGACELGPA--------------------------AE-AAPMSLAIHSTTGTRYDLAVPPDETVEGLRKRLSQRLKVPKERLALLHKDTRLSSGKLQEFGVGDGSKLTLVPTVEAGLMSQASRPEQSVMQALESLTETQ-------------------------------------------VSDFLSGRSPLTLALRVGDHMMFVQLQLAAQHAP---------------------------------------------LQHRHVLAAAAA---------AAAAR-GDPSIAS-----------------------------------------------------------------------------------------------------------------------------------------------------------------------PVSSPCRP----VSSAARVPPVPTSPS---------------PASPSP---------------------------------------------------------------------------------------------------------------------------------------------------ITAGSFRSHAASTTCPEQMDCSPT------------------------------------------------------------------------------------ASSSASPGASTTSTPGAS--PAPRSRKPGAVIESFVNHAPGVFSGTFSGTLHPNCQDSSGRPRRDIGTILQILNDLLSATRHYQG--------------------------------------------------------MPPSLAQLRCHAQCS-PASPAP----------DLAPRTTSCEKLTAAPSASLLQGQS-----------QIRMCKPPGDRLR---------QTENRATRCKVERLQLLLQQKRLRRKARRDARGPYHWSPSRKAGR---------------------------------------------------SDSSSSGGGGSPSEASGLGLDFEDSVWKPEVNPDIKSEFVVA------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6NYU6-1", "uniprot_id": "MIDN_DANRE", "id": "Q6NYU6-1", "name": "Midnolin", "aln": "-----------MDQHP-SARSCSSRGAAPSCES-----------------------------VSGEPPMNLYIHSTTGTRFELSLPAEETVEGLKRRLSQRLKVPKERLALLHKETRLSSGKLQDLGITDGSKLTLVPTVEAGLMSQASRPEQSVMQALESLTETQ-------------------------------------------VSDFLSGRSPLTLALRVGDHMMFVQLQLAAQPSGG------------------------------------------PQLQHRHLISRGSSEGTTGLSHGASGSASGMARVSHN-----------------------------------------------------------------------------------------------------------------------------------------------------------------PHPHHPHQHPHHPNTTLPSNPAAFPPSPSIPSIPPMYSTSASGHCSPPPQPSQ---------------------------------------------------------------------------------------------------------------------------------------------------LPGSFLHSQQPSSACAPSPSSPSP------------------------------------------------------------------------------------AASCPEASCSAKTSGNCN--TPLRSRKPGAIIESFVNHAPGVFSGTFSGTLHPNCQDSTGRPRRDIGTILQILNDLLSATRHYQG--------------------------------------------------------MPPSLTQLRYQTQCTSPNSPAPSPPPSPPHTTGLTGLPTTVPSETQPTLHPLVQCQS-----------QIRMCKPPGDRLR---------QTENRATRCKVERLQLLMQQKRLRRKARRDSRAPYHWLPNRKAGR---------------------------------------------------SNSNSS----MSSEGS-LDLDFEDSVWKPDVKADMKSEFIMA------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q8SXD4-1", "uniprot_id": "MIDN_DROME", "id": "Q8SXD4-1", "name": "Midnolin homolog", "aln": "MDKSAATNSATADGQNEAAAAAAAAATAAGCGSNNSSSTSSSNNTANSNNALQRLATTTSAVVASPMTINLNISTTTGGNFGVSVEPHISVESLKKIIAKKLKVAKDRICLLHREKELQDGTLRDHNLMDGSKIILIPNVETGLLAQR--PENTVMQALESLNDAQ-------------------------------------------VNDFLSGKTPLNLSMRLGDHMMLIQLQLSTVNPAGGGAATVAPVAGGASGSSINAAASTTSTVPVMPAGTGCSGANSTSLSSSAVLAAAAAGVGGSTGTSGSGTSSSSSSTSSSSSSSSSSSRTRSSGQRSSGRIGHGHVHSHQHPSLHAANWHGFSHGHGHGHSHGNGHGHHHHHHHHHHHHHHHHNASAVAAGSGGGMSSLRKMYGDLPSSSGASGSAPATGTGQSQSSSTLNGPDLTKLLIKGGIQNIVNSFALKDAGANARPVANGGSGSSPGKPVLEQSPIKSLSNLVSSPIKMTTIKNIPLPTTAATSSSSSCNCSSAAPSSSSSTSSGACATGGCQQDPIAAKLTSCLCTRLPTPSVAPPVATLVAPAPVARSGSTSSPSKCPESSCSGANAGFAARSTLAGTRVTFSGNSMLHKTGNNRITRTKHRHYHGQGHGHGHGNGHSSSSSSSSSSSSSHFFNHACAGNQPSVNAAAFATSSSSSSSSPSSSSSSPSKRRKLEQGMGAGAVGATAATATAAATVALPASTSATTAEPDDSLLGVSDTRTLAEASRNLTQTLRKLSKEVFTNKIDLSGAGVVSSGRSSSSGATSSGAASGEEAPRKSGSGAVIESMKNHGKGIYSGTFSGTLNPALQDRFGRPKRDISTVIHILNDLLSATPQYGRGARISFEAPTTGSVSGSGSGSGSSGSSSTTSSGSGLHHGSRSKMYSSKHHNCAKCNSRAQQQQQQSATLASGSGGSCSFRDCPSYHSSSAATKASTSSKSSSHSCCQTAEAPSSMTSQSNGCTCRYRRDDGQGEREREHTCQKCTVELANMKTRSKMDQLRLVMQQHKQKREARKLKSGPYATAASASAADSLSSIAAGGTAAVPMGAAAQYSAVSALVATPLQPAAVPVQTGKAAPANSITGNSSNANVNGNTSTAPATAATSAAAAPTAAPPSEVSPNHIVEEVDTAA", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : .* :. ... .* . .:.* * :*** .: ::: . :**.*:: ::::***.*:*:.***::..*..*.*:: .: ****: *:*.**:**::* **::********.::* *.*****::**.*::*:*****::****:: . *. ::: .:: .:.: . . : . * :. *.. ... . * . ** : .. : : .*::.. . ..... .:* .:.:: .. . *. .**:***: **. *::********:* ** ***:***.*:::********* :* .. * : : .: . .... . : .:: . : : * : * . *:* * : * **.*:::*:*::**:: :*:**: .** .. .*. .:*..: .* .. :. .. .::..:.:: ", "identical_positions": 129, "similar_positions": 191, "identity": "11.05%" }, { "cls_id": "homologset.agr.MGI:1890226", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9D164-1", "uniprot_id": "FXYD6_MOUSE", "id": "Q9D164-1", "name": "FXYD domain-containing ion transport regulator 6", "aln": "METVLV-LCSLLAPVVLASAAEKEKEKDPFYYDYQTLRIGGLVFAVVLFSVGILLILSRRCKCSFNQKPRAPGDEEAQVENLITTNAAEPQKAEN", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q91XV6-1", "uniprot_id": "FXYD6_RAT", "id": "Q91XV6-1", "name": "FXYD domain-containing ion transport regulator 6", "aln": "METVLI-LCSLLAPVVLASAAEKEKEKDPFYYDYQTLRIGGLVFAVVLFSVGILLILSRRCKCSFNQKPRAPGDEEAQVENLITTNAAEPQKAEN", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9H0Q3-1", "uniprot_id": "FXYD6_HUMAN", "id": "Q9H0Q3-1", "name": "FXYD domain-containing ion transport regulator 6", "aln": "MELVLVFLCSLLAPMVLASAAEKEKEMDPFHYDYQTLRIGGLVFAVVLFSVGILLILSRRCKCSFNQKPRAPGDEEAQVENLITANATEPQKAEN", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P58550-1", "uniprot_id": "FXYD8_HUMAN", "id": "P58550-1", "name": "Putative FXYD domain-containing ion transport regulator 8", "aln": "MEVVLIFVYSLLVPVVLASAA-KEKEIDPFHYNYQTLRIGGLVFDVVLFLVPSCHLLSHRCKCSFNQKPQDPGDKEAQVENFITANAKEPQKAKN", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "** **: : ***.*:****** **** ***:*:*********** **** * :**:**********: ***:******:**:** *****:*", "identical_positions": 69, "similar_positions": 13, "identity": "72.63%" }, { "cls_id": "homologset.agr.MGI:1890257", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0ABK0L9Q3-1", "uniprot_id": "A0ABK0L9Q3_RAT", "id": "A0ABK0L9Q3-1", "name": "Taste receptor type 2", "aln": "MVVTMRAALRLMLISTVSLELIIGILANVFIALVNIIDWIKRGKISAVDKIYMGLAISRTAFVLSLITGFLIAFLDPASLGIGIMIRLLTISWTVTNHFSVWFATCLSIFYFLKITNFSNTVFLALKWKVKKVVSVTLVVSLIILFINV---IVIHIYTDR----FQVNMVQKCGANNTLRAYGLFLSISTVFTFIPFTTSLTMFLLLIFSLWRHLKTMHHNATGSRDVSTVAHIKGLQTVVAFLLLYTVFAMSLFSQSLSIDAQHTNLLSHFLRCIGVAFPSGHSCALILGNNKLRQASLSVIFWLRCKYKHTENQGP-------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9JKA3-1", "uniprot_id": "TR103_MOUSE", "id": "Q9JKA3-1", "name": "Taste receptor type 2 member 103", "aln": "MVLTIRAILWVTLITIISLEFIIGILGNVFIALVNIIDWVKRGKISAVDKTYMALAISRTAFLLSLITGFLVSLLDPALLGMRTMVRLLTISWMVTNHFSVWFATCLSIFYFLKIANFSNSIFLVLKWEAKKVVSVTLVVSVIILIMNI---IVINKFTDR----LQVNTLQNCSTSNTLKDYGLFLFISTGFTLTPFAVSLTMFLLLIFSLWRHLKNMCHSATGSRDVSTVAHIKGLQTVVTFLLLYTAFVMSLLSESLNINIQHTNLLSHFLRSIGVAFPTGHSCVLILGNSKLRQASLSVILWLRYKYKHIENWGP-------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9NYV8-1", "uniprot_id": "T2R14_HUMAN", "id": "Q9NYV8-1", "name": "Taste receptor type 2 member 14", "aln": "MGGVIKSIFTFVLI----VEFIIGNLGNSFIALVNCIDWVKGRKISSVDRILTALAISRISLVWLIFGSWCVSVFFPALFATEKMFRMLTNIWTVINHFSVWLATGLGTFYFLKIANFSNSIFLYLKWRVKKVVLVLLLVTSVFLFLNI---ALINIHINASINGYRRNKTCSSDSSNFTRFSSLIVLTSTVFIFIPFTLSLAMFLLLIFSMWKHRKKMQHTVKISGDASTKAH-RGVKSVITFFLLYAIFSLSFFISVWTSERLEENLI-ILSQVMGMAYPSCHSCVLILGNKKLRQASLSVLLWLRYMFKDGEPSGHKEFRESS", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q58WW8-1", "uniprot_id": "Q58WW8_DANRE", "id": "Q58WW8-1", "name": "Taste receptor type 2", "aln": "MEPWLYALISSPLC-------LIGMVFN-LLFFFCLMRPVSGVTLRNPLRFLLIVVLVNSTFQYLVIAVTIIMLLFDYIFWLETVTRALIYQFFCG---NFLCNAWISIFYYISIVPQHHAIFIWIKRNIKAILYGGFILNQIVLTFAISTGAVTYFFLGPVPVNFTALELNSTALAQTLEADMFLFHVANFSYLLYCTCPLVTLIVSWGKTFFYLRGHMKKMGQSGESFSQPQQKSQMRVTVTGMVQAALFLP--SSLWTVAAALLYITGLFEEVDPSRFITMTFCSLSSLGNLLCFGFSQSVFRRGIVSVIKKLKG--------", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* : : : * :** : * :: :. : :. .: : :.: . :: :: : .: : : * * : .. : :. **::.*. :::*: :* . * :: :::. :.* : : : . . . : . ::. :. : : .*. ::: . : : : :. * : : .: :. * . :: : : :. . . : : . : : * * .. * . . :: : * ", "identical_positions": 21, "similar_positions": 105, "identity": "6.44%" }, { "cls_id": "homologset.agr.MGI:1890258", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q67ER8-1", "uniprot_id": "TR116_RAT", "id": "Q67ER8-1", "name": "Taste receptor type 2 member 116", "aln": "MNGVLYITFTVILSVEVIIGNFGNGIIALVNIMDLAKRRKISSVDQILTALAISRIVLLWLVLVSWWLSMFYPGQWMTEGIDVIVHNVWTTLNQISLWLATSFSVFCFLKVANFSNTIFFYLKIRVKKVMTGTLIMFLLLLGLNIIVINASKTILIPEYKVNMSNSLNLKN-TQISMLFPFANTLFGFIPFAVSLVTFLLLFFSLWKHQRKMHHGAQGCRDSSTKAHIRVLQTLIASILLYFVFFLSLVVKVWISLFLERMLLLLITQAAKIAFPSLHPWVLILGNAKLRKASLSALQWLRCRHKDEHRRVQRPEVHSCGSSCMP", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q7M713-1", "uniprot_id": "TR116_MOUSE", "id": "Q7M713-1", "name": "Taste receptor type 2 member 116", "aln": "MNGVLQVTFIVILSVEFIIGIFGNGFIAVVNIKDLVKGRKISSVDQILTALAISRIALLWLILVSWWIFVLYPGQWMTDRRVSIMHSIWTTFNQSSLWFATSLSIFYFFKIANFSNPIFLYLKVRLKKVMIGTLIMSLILFCLNIIIMNAPENILITEYNVSMSYSLILNN-TQLSMLFPFANTMFGFIPFAVSLVTFVLLVFSLWKHQRKMQHSAHGCRDASTKAHIRALQTLIASLLLYSIFFLSHVMKVWSALLLERTLLLLITQVARTAFPSVHSWVLILGNAKMRKASLYVFLWLRCRHKE-------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9NYV8-1", "uniprot_id": "T2R14_HUMAN", "id": "Q9NYV8-1", "name": "Taste receptor type 2 member 14", "aln": "MGGVIKSIFTFVLIVEFIIGNLGNSFIALVNCIDWVKGRKISSVDRILTALAISRISLVWLIFGSWCVSVFFPALFATEKMFRMLTNIWTVINHFSVWLATGLGTFYFLKIANFSNSIFLYLKWRVKKVVLVLLLVTSVFLFLNIALINIHINASINGYRRNKTCSSDSSNFTRFSSLIVLTSTVFIFIPFTLSLAMFLLLIFSMWKHRKKMQHTVKISGDASTKAH-RGVKSVITFFLLYAIFSLSFFISVWTSERLEEN-LIILSQVMGMAYPSCHSCVLILGNKKLRQASLSVLLWLRYMFKDGEPSGHKEFRESS------", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*.**: * .:* **.*** :**.:**:** * .* *******:********** *:**:: ** : :::*. : *: :: .:**.:*: *:*:**.:. * *:*:*****.**:*** *:***: *:: ::: *** ::* . * *. . : * .* *::* *: ::.*:* ****::**. *:**.**:***::**:* .: . *:***** * ::::*: :*** :* ** .:.** : **. *::::*. *:** *. ****** *:*:*** .: *** .*: ", "identical_positions": 136, "similar_positions": 96, "identity": "41.85%" }, { "cls_id": "homologset.agr.MGI:1890357", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9NZI8-1", "uniprot_id": "IF2B1_HUMAN", "id": "Q9NZI8-1", "name": "Insulin-like growth factor 2 mRNA-binding protein 1", "aln": "MNKLYIGNLNESVTPADLEKVFAEHKISYSGQFLVKSGYAFVDCPDEHWAMKAIETFSGKVELQGKRLEIEHSVPKKQRSRKIQIRNIPPQLRWEVLDSLLAQYGTVENCEQVN-TESETAVVNVTYSNREQTRQAIMKLNGHQLENHALKVSYIPDEQ----IAQGPENGRRGGFGSRGQPRQGSPVAAGAPAKQQQVDIPLRLLVPTQYVGAIIGKEGATIRNITKQTQSKIDVHRKENAGAAEKAISVHSTPEGCSSACKMILEIMHKEAKDTKT------ADEVPLKILAHNNFVGRLIGKEGRNLKKVEQDTETKITISSLQDLTLYNPERTITVKGAIENCCRAEQEIMKKVREAYENDVAAMSLQSHLIPGLNLAAVGLFPASSSAVPPPP---------SSVTGAAPYSSFMQAPEQEMVQVFIPAQAVGAIIGKKGQHIKQLSRFASASIKIAPPETPD----SKVRMVIITGPPEAQFKAQGRIYGKLKEENFFGPKEEVKLETHIRVPASAAGRVIGKGGKTVNELQNLTAAEVVVPRDQTP---DENDQVIVKIIGHFYASQMAQRKIRDILA----------------QVKQQHQKG-------------------QSNQAQARRK---------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8CGX0-1", "uniprot_id": "IF2B1_RAT", "id": "Q8CGX0-1", "name": "Insulin-like growth factor 2 mRNA-binding protein 1", "aln": "MNKLYIGNLNESVTPADLEKVFAEHKISYSGQFLVKSGYAFVDCPDEHWAMKAIETFSGKVELQGKRLEIEHSVPKKQRSRKIQIRNIPPQLRWEVLDSLLAQYGTVENCEQVN-TESETAVVNVTYSNREQTRQAIMKLNGHQLENHALKVSYIPDEQ----IAQGPENGRRGGFGSRGQPRQGSPVAAGAPAKQQQVDIPLRLLVPTQYVGAIIGKEGATIRNITKQTQSKIDVHRKENAGAAEKAISVHSTPEGCSSACKMILEIMHKEAKDTKT------ADEVPLKILAHNNFVGRLIGKEGRNLKKVEQDTETKITISSLQDLTLYNPERTITVKGAIENCCRAEQEIMKKVREAYENDVAAMSLQSHLIPGLNLAAVGLFPASSSAVPPPP---------SSVTGAAPYGSFMQAPEQEMVQVFIPAQAVGAIIGKKGQHIKQLSRFASASIKIAPPETPD----SKVRMVVITGPPEAQFKAQGRIYGKLKEENFFGPKEEVKLETHIRVPASAAGRVIGKGGKTVNELQNLTAAEVVVPRDQTP---DENDQVIVKIIGHFYASQMAQRKIRDILA----------------QVKQQHQKG-------------------QSNQAQARRK---------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O88477-1", "uniprot_id": "IF2B1_MOUSE", "id": "O88477-1", "name": "Insulin-like growth factor 2 mRNA-binding protein 1", "aln": "MNKLYIGNLNESVTPADLEKVFAEHKISYSGQFLVKSGYAFVDCPDEHWAMKAIETFSGKVELQGKRLEIEHSVPKKQRSRKIQIRNIPPQLRWEVLDSLLAQYGTVENCEQVN-TESETAVVNVTYSNREQTRQAIMKLNGHQLENHALKVSYIPDEQ----ITQGPENGRRGGFGSRGQPRQGSPVAAGAPAKQQPVDIPLRLLVPTQYVGAIIGKEGATIRNITKQTQSKIDVHRKENAGAAEKAISVHSTPEGCSSACKMILEIMHKEAKDTKT------ADEVPLKILAHNNFVGRLIGKEGRNLKKVEQDTETKITISSLQDLTLYNPERTITVKGAIENCCRAEQEIMKKVREAYENDVAAMSLQSHLIPGLNLAAVGLFPASSSAVPPPP---------SSVTGAAPYSSFMQAPEQEMVQVFIPAQAVGAIIGKKGQHIKQLSRFASASIKIAPPETPD----SKVRMVVITGPPEAQFKAQGRIYGKLKEENFFGPKEEVKLETHIRVPASAAGRVIGKGGKTVNELQNLTAAEVVVPRDQTP---DENDQVIVKIIGHFYASQMAQRKIRDILA----------------QVKQQHQKG-------------------QSNLAQARRK---------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q08CK7-1", "uniprot_id": "IF2B1_DANRE", "id": "Q08CK7-1", "name": "Insulin-like growth factor 2 mRNA-binding protein 1", "aln": "MNKLYIGNLNEKVTAEDLVKTFEDYKIPYSGQFLMKTGYASVDCPDDQWAMKAIETFSGKVELHGKRIEVEHSVPKKQRTRKLQIRNIPPHLQWEVLDGLLAQYGTVENCEQVN-TDSETAVVNVTYGTREQARQAIQKLNGYQFDNNALRVSYIPDENSEVDSQRGPDNGRRPGYGPRGTSRQMSP-GSGIPSKHQHADIPLRLLVPTQYVGAIIGKEGATIRNITKQTQSKIDVHRKENAGAAEKPISIHSTPEGCSAACRMILEIMNQEAKDTKT------ADEVPLKVLAHNNFVGRLIGKEGRNLKKVEQDTDTKITISPLQDLTLYNPERTITVKGSIEACCLAEQEIMKKVREAYDNDIAAMNQQTHLIPGLNLGAIGLFPPSSAMPPPAL---------GNSVPGPPYG-PMGASEQETVHVYIPAQAVGALIGKKGQHIKQLSRFAGASIKIAPAEAPD----SKMRMVIVTGPPEAQFKAQGRIYGKLKEENFFGPKEEVKLETHIKVAAAAAGRVIGKGGKTVNELQNLTAAEVVVPREQTP---DEHDQVIVKIIGHFYASQLAQRKIRDILT----------------QVKQQQKGGGMGTPQGPHPQGMTELGSPQGLAQEPRRK---------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "M9NF14-1", "uniprot_id": "M9NF14_DROME", "id": "M9NF14-1", "name": "", "aln": "--------------MASELDQFADLELSK-------------------------EDREQIFDPPLDRQQLEGAGTSSVTTSKILISGIPMQTRFEDIEPLLKPYGIVKQCEAISSKDQNTQTVHITFENPEQAQRAAVGLNGVEFEGSKLHAEQLDKNQ-------------------RRSQRNQRNPYPGMPGPGRQADFPLRILVQSEMVGAIIGRQGSTIRTITQQSRARVDVHRKENVGSLEKSITIYGNPENCTNACKRILEVMQQEAISTNKGELSPECSEICLKILAHNNLIGRIIGKSGNTIKRIMQDTDTKITVSSINDINSFNLERIITVKGLIENMSRAENQISTKLRQSYENDLQAMAPQSLMFPGLHPMAMMSTPGNGMVFNTSMPFPSCQSFAMSKTPASVVPPVFPNDLQETTYLYIPNNAVGAIIGTRGSHIRSIMRFSNASLKIAPLDADKPLDQQTERKVTIVGTPEGQWKAQYMIFEKMREEGFMCGTDDVRLTVELLVASSQVGRIIGKGGQNVRELQRVTGSVIKLPEHALAPPSGGDEETPVHIIGLFYSVQSAQRRIRAMMLSTNPPPITKKQKAAKEQLQQQQQSLAGAASSGSQQQQPQSPSQQQALPPQLHHQPVSSASSSSTPPAHHQQQASTAATSHQLQQQQPSPPPPGNATAAAAQQQQQLASSQQ", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . . * : ::. * . .: .* ::* : ... : *: * .** : ::* :: ** ** *::** :. .:.:* .*::*: . **:::* *** :::. *:.. : .:: * *: .* *. : .*:***:** :: ******::*:***.**:*:::::*******.*: **.*:::..**.*: **: ***:*::** .*:. ..*: **:*****::**:***.*..:*:: ***:****:*.::*:. :* ** ***** ** . **::* .*:*::*:**: ** *: ::***: *: * .. .. . . .. : ** . ::** :****:**.:*.**:.: **:.**:**** :: . .. * * :.*.**.*:*** *: *::**.*: .::*:* ..: *.:: .**:*****:.*.***.:*.: : :*.. . . .::. *:*** **: * ***:** :: *::**:: *. : ::: ", "identical_positions": 189, "similar_positions": 203, "identity": "27.16%" }, { "cls_id": "homologset.agr.MGI:1890358", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZWZ6-1", "uniprot_id": "D3ZWZ6_RAT", "id": "D3ZWZ6-1", "name": "Insulin-like growth factor 2 mRNA-binding protein 2", "aln": "MMNKLYIGNLSPAVTADDLRQLFGDRKLPLAGQVLLKSGYAFVDYPDQNWAIRAIETLSGKVELHGKIMEVDYSVSKKLRSRKIQIRNIPPHLQWEVLDGLLAEYGTVENVEQVNT-DTETAVVNVTYMTREEAKVAIEKLSGHQFEDYSFKISYIPDEELSSPSPP-------HRAREQGHGPGSS-----SQARQIDFPLRILVPTQFVGAIIGKEGLTIKNITKQTQSRVDIHRKENSGAAEKPVTIHATPEGTSEACRMILEIMQKEADETK------LAEEVPLKILAHNGFVGRLIGKEGRNLKKIEHETGTKITISSLQDLSIYNPERTITVKGTIEACASAEMEIMKKLREAFENDMLAVNQQANLIPGLNLSALGIFSTGLSVLPPPAGPRGAPPSPP--YHPFATHSGYFSSLYPHHHFGPFPHHHS-YPEQETVSLFIPTQAVGAIIGKKGAHIKQLARFAGASIKIAPAEGPD----VSERMVIITGPPEAQFKAQGRIFGKLKEENFFNPKEEVKLEAHIRVPSSTAGRVIGKGGKTVNELQNLTSAEVIVPRDQTP---DENEEVIVRIIGHFFASQTAQRKIREIVQQVK---------------QQAQKYPQG-VAPQ-RSK---------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q5SF07-1", "uniprot_id": "IF2B2_MOUSE", "id": "Q5SF07-1", "name": "Insulin-like growth factor 2 mRNA-binding protein 2", "aln": "MMNKLYIGNLSPAVTADDLRQLFGDRKLPLAGQVLLKSGYAFVDYPDQNWAIRAIETLSGKVELHGKIMEVDYSVSKKLRSRRIQIRNIPPHLQWEVLDGLLAEYGTVENVEQVNT-DTETAVVNVTYMTREEAKLAIEKLSGHQFEDYSFKISYIPDEEVSSPSPP-------HRAREQGHGPGSS-----SQARQIDFPLRILVPTQFVGAIIGKEGLTIKNITKQTQSRVDIHRKENSGAAEKPVTIHATPEGTSEACRMILEIMQKEADETK------LAEEVPLKILAHNGFVGRLIGKEGRNLKKIEHETGTKITISSLQDLSIYNPERTITVRGTIEACANAEIEIMKKLREAFENDMLAVNQQANLIPGLNLSALGIFSTGLSVLPPPAGPRGVPPSPP--YHPFATHSGYFSSLYPHHHFGPFPHHHS-YPEQETVSLFIPTQAVGAIIGKKGAHIKQLARFAGASIKIAPAEGPD----VSERMVIITGPPEAQFKAQGRIFGKLKEENFFNPKEEVKLEAHIRVPSSTAGRVIGKGGKTVNELQNLTSAEVIVPRDQTP---DENEEVIVRIIGHFFASQTAQRKIREIVQQVK---------------QQEQRYPQG-VAPQ-RSK---------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9Y6M1-2", "uniprot_id": "IF2B2_HUMAN", "id": "Q9Y6M1-2", "name": "Insulin-like growth factor 2 mRNA-binding protein 2", "aln": "MMNKLYIGNLSPAVTADDLRQLFGDRKLPLAGQVLLKSGYAFVDYPDQNWAIRAIETLSGKVELHGKIMEVDYSVSKKLRSRKIQIRNIPPHLQWEVLDGLLAQYGTVENVEQVNT-DTETAVVNVTYATREEAKIAMEKLSGHQFENYSFKISYIPDEEVSSPSPPQRAQRGDHSSREQGHAPGGT-----SQARQIDFPLRILVPTQFVGAIIGKEGLTIKNITKQTQSRVDIHRKENSGAAEKPVTIHATPEGTSEACRMILEIMQKEADETK------LAEEIPLKILAHNGLVGRLIGKEGRNLKKIEHETGTKITISSLQDLSIYNPERTITVKGTVEACASAEIEIMKKLREAFENDMLAVNQQANLIPGLNLSALGIFSTGLSVLSPPAGPRGAPPAAP--YHPFTTHSGYFSSLYPHHQFGPFPHHHS-YPEQEIVNLFIPTQAVGAIIGKKGAHIKQLARFAGASIKIAPAEGPD----VSERMVIITGPPEAQFKAQGRIFGKLKEENFFNPKEEVKLEAHIRVPSSTAGRVIGKGGKTVNELQNLTSAEVIVPRDQTP---DENEEVIVRIIGHFFASQTAQRKIREIVQQVK---------------QQEQKYPQG-VASQ-RSK---------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A0B4J1B0-1", "uniprot_id": "A0A0B4J1B0_DANRE", "id": "A0A0B4J1B0-1", "name": "", "aln": "-MNKLYVGNLSPSVTVEDLKQLFGERKLPVTDQVLLKSGYAFVDFPDQNWAIKAIETLSGKVELHGKVIEVDYSVPKKLRSRKIQIRNIPPHLQWEVLDSLLAQYGTVENVEQVNT-DTETAVVNVTYSTKEEAKVAVEKLIEQTFEDYSFKVSYIMDMDAAAALPGTRNRRGGRTSREQDSQPGTSGSSLGSRQKQPDFPLRMLVPTQFVGAIIGKEGLTIKNITKQTQSKVDIHRKENAGAAEKPITIHSTPEGCSTACHMIMDIMQKEAVDTK------VTEDIPLKILAHNSLVGRLIGKEGRNLKKIEEDTETKITISSLQDLTIYNPERTIIVKGSIEACCRAEVEIMKKLREAYENDVAAINQQSNLIPGLSLSALGIFSTGLSVLPPAAGPRGIPPVPPTGYNPFLGHSSQLGGLYGVPPASGISHQHTQAPEQEVVYLFIPTQAVGAIIGKKGQHIKQLARFAGASIKIAPAESPD----VTQRMVIITGPPEAQFKAQGRIFGKLKEENFFTAKEEVKLETHIKVPSSAAGRVIGKGGKTVNELQNLTSAEVIVPRDQTP---DENDEVFVKISGHFFASQTAQRKIREIIQQVK---------------QQEQKHQQG-APTTPRSK---------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A0R4IVY2-1", "uniprot_id": "A0A0R4IVY2_DANRE", "id": "A0A0R4IVY2-1", "name": "", "aln": "--------------------------------------------------------MVTGSREQE------------------------------------FGQPGAMG-------------------------------------------------------------------------GPQGP------RQRQQELPLRILVPTQFVGAIIGKEGLTIKNITKQTQSKVDIHRKENAGATEKAITIHSSKEGCSQACRMILEIMEKEANDTK------IVEEVPLKILAHNSLVGRLIGKEGRNLKKIEQDTGTKITISALQDLTVYNQERTISVRGGVEECCKAEGEIMKKLREAHENDVASVNQQTNMMAGLNLSALGIFSSGMSVLPPASGLRGSLSTPAN-YSPLLGPS-IMGGLYGVPSSGALSLQQA-GGEQEVVYLFIPTPAVGALIGKKGQHIKELAHFAGASIKIAAPESPD----EPERMVIITGPPEAQFKAQGRIYGKLKEENFFTAKEEVKLEAHIKVPSTAAGRVIGKGGKTVNELQNLTSAEVIVPRDQTP---DENDDVFVKIIGHFFASQTAQRKIREIVQQVK---------------QQERKHQQMPQTPSEQSN---------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "M9NF14-1", "uniprot_id": "M9NF14_DROME", "id": "M9NF14-1", "name": "", "aln": "-MASELDQFADLELSKEDREQIFDP---PLDRQQLEGAG--------------TSSVTTSKILISG----------------------IPMQTRFEDIEPLLKPYGIVKQCEAISSKDQNTQTVHITFENPEQAQRAAVGLNGVEFEGSKLHAEQLDKNQRRSQRNQ------------RNPYPGMP-----GPGRQADFPLRILVQSEMVGAIIGRQGSTIRTITQQSRARVDVHRKENVGSLEKSITIYGNPENCTNACKRILEVMQQEAISTNKGELSPECSEICLKILAHNNLIGRIIGKSGNTIKRIMQDTDTKITVSSINDINSFNLERIITVKGLIENMSRAENQISTKLRQSYENDLQAMAPQSLMFPGLHPMAMMSTPGNGMVFNTSMPFPSCQSFAMS-----KTPASVVPPVFPN-------------DLQETTYLYIPNNAVGAIIGTRGSHIRSIMRFSNASLKIAPLDADKPLDQQTERKVTIVGTPEGQWKAQYMIFEKMREEGFMCGTDDVRLTVELLVASSQVGRIIGKGGQNVRELQRVTGSVIKLPEHALAPPSGGDEETPVHIIGLFYSVQSAQRRIRAMMLSTNPPPITKKQKAAKEQLQQQQQSLAGAASSGSQQQQPQSPSQQQALPPQLHHQPVSSASSSSTPPAHHQQQASTAATSHQLQQQQPSPPPPGNATAAAAQQQQQLASSQQ", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :.. : * : * . :* ::***:** :::******::* **:.**:*::::**:***** *: **.:**:.. *. : **: *:::*::** .*: .:: *******.::**:***.*..:*:* .:* ****:*:::*:. :* ** * *:* :* . ** :* .***::.***: :: *: ::.** *: . . *: .. . . . : . :: ** . *:**. ****:**.:* **:.: :*:.**:***. :. . .:* * *.*.**.*:*** *: *::**.*: .::*:* ..: *.*: .**:*****:.*.***.:*.: : :*.. . . :::. *:* * *:: *:***:** :: ..: ** :: .. :.: ", "identical_positions": 147, "similar_positions": 161, "identity": "20.62%" }, { "cls_id": "homologset.agr.MGI:1890359", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A0G2K0Y2-1", "uniprot_id": "A0A0G2K0Y2_RAT", "id": "A0A0G2K0Y2-1", "name": "", "aln": "MNKLYIGNLSDHAGPADLESVFKDAKIPVAGPFLVKTGYAFVDCPDEGWALKAIEALSGKMELHGKPMEVEHSVPKRQRIRKLQIRNIPPHLQWEVLDSLLVQYGVVESCEQVN-TDSETAVVNVTYSSKDQARQALDKLNGFQLENFTLKVAYIPDETAAQQSPSPQLRGRRGPGQRGSSRQTSPGSVSKQK-PCDLPLRLLVPTQFVGAIIGKEGATIRNITKQTQSKIDVHRKENTGAAEKSITILSTPEGTSAACKSILEIMHKEAQDIKFT------EEIPLKILAHNNFVGRLIGKEGRNLKKIEQDTDTKITISPLQELTLYNPERTITVKGNVETCAKAEEEIMKKIRESYENDIASMNLQAHLIPGLNLNALGLFP------PTSG--MPPPTSGPPSAMTPPYPQF-EQSETETVHLFIPALSVGAIIGKQGQHIKQLSRFAGASIKIAPAEAPD----AKVRMVIITGPPEAQFKAQGRIYGKIKEENFVSPKEEVKLEAHIRVPSFAAGRVIGKGGKTVNELQNLSSAEVVVPRDQTP---DENDQVVVKITGHFYACQVAQRKIQEILTQVK-------------QHQQQKALQSGAPQSRRK-----------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9CPN8-1", "uniprot_id": "IF2B3_MOUSE", "id": "Q9CPN8-1", "name": "Insulin-like growth factor 2 mRNA-binding protein 3", "aln": "MNKLYIGNLSDHAGPADLESVFKDAKIPVAGPFLVKTGYAFVDCPDEGWALKAIEALSGKMELHGKPMEVEHSVPKRQRIRKLQIRNIPPHLQWEVLDSLLVQYGVVESCEQVN-TDSETAVVNVTYSSKDQARQALDKLNGFQLENFTLKVAYIPDETAAQQNPSPQLRGRRGPGQRGSSRQASPGSVSKQK-PCDLPLRLLVPTQFVGAIIGKEGATIRNITKQTQSKIDVHRKENTGAAEKSITILSTPEGTSAACKSILEIMHKEAQDIKFT------EEIPLKILAHNNFVGRLIGKEGRNLKKIEQDTDTKITISPLQELTLYNPERTITVKGSVETCAKAEEEIMKKIRESYENDIASMNLQAHLIPGLNLNALGLFP------PTSG--MPPPTSGPPSTLTPPYPQF-EQSETETVHLFIPALSVGAIIGKQGQHIKQLSRFAGASIKIAPAEAPD----AKVRMVIITGPPEAQFKAQGRIYGKIKEENFVSPKEEVKLEAHIRVPSFAAGRVIGKGGKTVNELQSLSSAEVVVPRDQTP---DENDQVVVKITGHFYACQVAQRKIQEILTQVK-------------QHQQQKALQSGPPQSRRK-----------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O00425-1", "uniprot_id": "IF2B3_HUMAN", "id": "O00425-1", "name": "Insulin-like growth factor 2 mRNA-binding protein 3", "aln": "MNKLYIGNLSENAAPSDLESIFKDAKIPVSGPFLVKTGYAFVDCPDESWALKAIEALSGKIELHGKPIEVEHSVPKRQRIRKLQIRNIPPHLQWEVLDSLLVQYGVVESCEQVN-TDSETAVVNVTYSSKDQARQALDKLNGFQLENFTLKVAYIPDEMAAQQNPLQQPRGRRGLGQRGSSRQGSPGSVSKQK-PCDLPLRLLVPTQFVGAIIGKEGATIRNITKQTQSKIDVHRKENAGAAEKSITILSTPEGTSAACKSILEIMHKEAQDIKFT------EEIPLKILAHNNFVGRLIGKEGRNLKKIEQDTDTKITISPLQELTLYNPERTITVKGNVETCAKAEEEIMKKIRESYENDIASMNLQAHLIPGLNLNALGLFP------PTSG--MPPPTSGPPSAMTPPYPQF-EQSETETVHLFIPALSVGAIIGKQGQHIKQLSRFAGASIKIAPAEAPD----AKVRMVIITGPPEAQFKAQGRIYGKIKEENFVSPKEEVKLEAHIRVPSFAAGRVIGKGGKTVNELQNLSSAEVVVPRDQTP---DENDQVVVKITGHFYACQVAQRKIQEILTQVK-------------QHQQQKALQSGPPQSRRK-----------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9PW80-1", "uniprot_id": "IF2B3_DANRE", "id": "Q9PW80-1", "name": "Insulin-like growth factor 2 mRNA-binding protein 3", "aln": "MNKLYIGNVSEQASALDLESIFEQWKIPFSAPFLVKSGYAFVDCPDEKVAMRAIDTLSGKVELHGKVLEVEHSVPKRQRSCKLQIRNIPPHMQWEVLDGLLAQYGTVESCEQVN-TDTETAVVNVRYGAKDQAREAMDKLNGFLMENYALKVSYIPDETAAADAP--AVGGRRGFNPRGPPRQGSPSLGARPKLQSDVPLRLLVPTQFVGAIIGKEGATIRNITKQTHSKIDIHRKENAGAAEKPITVHSTPEGCSSACRNIMEIMQKEAIDTKIT------EEIPLKILAHNNFVGRLIGKEGRNLKKIEQDTDTKITISPLQDLTLYNPERTITVKGTLDACAKAEEEIMKKVRESYENDVAAMHLQSNLIPGLNLNALGLFPG-----AASGGISPSVVSGPPPGAQAGYQSFGAQMESETVHLFIPALAVGAIIGKQGQHIKQLSRFAGASIKIAPADGID----AKQRMVIISGPPEAQFKAQGRIFGKLKEENFFGPKEEVKLEAHIKVPSFAAGRVIGKGGKTVNELQNLTSAEVVVPRDQTP---DENDQVVVKITGHFYASQLAQRKIQEIISQVR-------------RQQQPKPSAAGPPVARRK-----------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "M9NF14-1", "uniprot_id": "M9NF14_DROME", "id": "M9NF14-1", "name": "", "aln": "-------MASELDQFADLELSKEDREQIFDPPLDRQQ--------------------------------LEGAGTSSVTTSKILISGIPMQTRFEDIEPLLKPYGIVKQCEAISSKDQNTQTVHITFENPEQAQRAAVGLNGVEFEGSKLHAEQLDKNQRR---------------SQRNQRNPYPGMPGPGR-QADFPLRILVQSEMVGAIIGRQGSTIRTITQQSRARVDVHRKENVGSLEKSITIYGNPENCTNACKRILEVMQQEAISTNKGELSPECSEICLKILAHNNLIGRIIGKSGNTIKRIMQDTDTKITVSSINDINSFNLERIITVKGLIENMSRAENQISTKLRQSYENDLQAMAPQSLMFPGLHPMAMMSTPGNGMVFNTSMPFPSCQSFAMSKTPASVVPPVFPNDLQETTYLYIPNNAVGAIIGTRGSHIRSIMRFSNASLKIAPLDADKPLDQQTERKVTIVGTPEGQWKAQYMIFEKMREEGFMCGTDDVRLTVELLVASSQVGRIIGKGGQNVRELQRVTGSVIKLPEHALAPPSGGDEETPVHIIGLFYSVQSAQRRIRAMMLSTNPPPITKKQKAAKEQLQQQQQSLAGAASSGSQQQQPQSPSQQQALPPQLHHQPVSSASSSSTPPAHHQQQASTAATSHQLQQQQPSPPPPGNATAAAAQQQQQLASSQQ", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *: *** :: : . *: : :* : .. *: * .** : ::* :: ** ** *:.** :. .* :* .*:: : :**:.* ***. :*. *:. : .: : *: *. . : .*.***:** :::******::*:***.**:*:::::*:*****.*: **.**: ..**. : **: *:*:*::** . : .** ********::**:***.*..:*:* ********:*.::::. :* ** ***** :: ::**::* .*:*:*****: :* *: ::***: *: * :* . . . . . : **.:*:** :******.:*.**:.: **:.**:**** :. . . * * * *.**.*:*** *: *::**.*. .::*:* ..: *.* .**:*****:.*.*** ::.: : :*.. . . :::. *:* * **: * ***:*: :: ... : ** : :*.. : : ", "identical_positions": 189, "similar_positions": 184, "identity": "27.27%" }, { "cls_id": "homologset.agr.MGI:1890373", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A0G2JZA7-1", "uniprot_id": "A0A0G2JZA7_RAT", "id": "A0A0G2JZA7-1", "name": "hyaluronoglucosaminidase", "aln": "MYAAGSRGHSPAFLQPQNGNGHRSPGYVPGKVVPFRPAPPPKNHASAKLTSRSQEAPATFAFSPEEQRTPREDRKQKRHKNTFICFAITSFSFFVTLAVILGISSKYAPDENCPDQNPRLRNWDPGQDSAKHIVIKEGDMLRLTSDATVNSIVIQDGGLLVFGDDKDGSRNITLRTRYILIQDGGALHIGAEKCRYRSKATITLYGKSDEHES--MPTFGKKFIGVEAGGTLELHGARRTSWTMLARTLHSSGLPFGSYAFEKDFSRGLNVRVIDQDTARVLEHEKFDTHEYHNESRRLQEFLRAQDPGRIVAIAVGDSAVKSLLQGTIQMIQDRLGSKLIQGLGYRQAWALVGVIDGGSSSCNESVRNYENHSTGGKALAQGEFYTLDGQKFSVTAYSEWIEGISLSGFRVDIADGVKLHLLDDVSSWGAGDRIVVASTDYSMYQAEELTLLPCPECSRFQVKVKEIPQYLHVGEIIDGIDMRAEVGLLTRNIVIQGETEDSCYADNHCQFFDYDTFGGHVMIEKNFTSVHLSYVELKHMGQQ-HLGRYPVHFHLCGDVDSKGGYRVPTSVNGLSIHHSFSRCITVHGSSGLLIKDTIGFDTLGHCFFLEDGVEQRNILFHNLGLLTKPGTLLPTDRNSSMCTVMRDGVFGNYIPVPTTDCMAVSTFWIAHPNNHLINNAAAGSQDAGIWYLFHKEPTGESSGMQLLEKPELTPLGIFYNNRVHSNFKAGLFVDKGVKTTNSSASDPREYLCLDNSARFRPHQDADPEKPRVAAVIDRLIAFKNNDNGAWVRGGDIIVQNSAFADNGKGLTFASDGSFPSDEGSSQEVSESLFVGESKNYGSQGGQNKYMGTGGIDQKPRTLPRNRTFPIRGFQIYDGPIHLTKSTFKKYVPTPDRYSSAIGFLMKNSWQTTPRNNVSLVKFGPQVSLNVFFGKPGPWFEDCELDGDKNSIFHDIDGSVTGYKDTYVGRMDNYLIRHPNCVSVTKWNAVVCSGTYAQVYVQTWNTPNLSMIITRDEYPSHPMVLRGINQR-AISPQYQPVVMLEKGYTIHWSGPAPRTTFLYLVNFNKDDWIRVGLCYPSNTSFQVTVGFLQRQNGSLSRIEEYEPAQSMEELQKKPSERKFYFDSGTGLLFLYLRAHSHRDGHSYCSSQGCERVKIQAATDS---KDMSNCMAKAYPQYYKKPSAVKRMPAMLTGFCQGCGTHQMVFSSDPHKSYLPVRFQSPGKAEIQRGE-PSVISVNGTDFTFRSAGAFLLIVDACSVPFRLTEKRMFLSADISHLEEYLKASIPPRSIVLLSTRGEIKQMN-ISDSFVLLGLAKPAHLYNKGSTVFLGFSGNFTPS---WTRLFTSPDVQGLGVLEQYLPLQMEEYGCS-RTSSVHRRDLELLQQALKGL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q5FWI3-1", "uniprot_id": "CEIP2_MOUSE", "id": "Q5FWI3-1", "name": "Cell surface hyaluronidase", "aln": "MYAAGSRGHSPAFLQPQNGNGHRSPGYVPGKVVPLRPAPPPKNHASAKLTSRSQDAPATFAFSPEEQRTPSESRKRKRHKNTFICFAITSFSFFVALAVILGISSKYAPDENCPDQNPRLRNWDPGQDSAKHIVIKEGDLFRLTSDATVDSIVIQDGGLLVFGDDKDGSKNITLRTRYILIQDGGALHIGAEKCRYRSKATITLYGKSDERES--MPIFGKKFIGVEAGGTLELHGAQRTSWTMLARTLHSSGLPFGSYAFEKDFSRGLNVRVIDQDTARVLENEKFDTHEYHNESRRLQEFLRAQEPGRIVAIAVGDSAVKSLLQGTIQMIQDRLGSKLIQGLGYRQAWALVGVIDGGSSSCNESVRNYENHSTGGKALAQGEFYTLDGQKFSVTAYSEWSQGISLSGFRVDIADGVKLHLLDDVSTWEAGDRIVVASTDYSMYQAEELTLLRCPECSRSQVKVKEIPQYLHVGEIIDGIDMRAEVGLLTRNIVIQGEMEDSCYAENHCQFFDYDTFGGHVMIEKNFTSVHLSYVELKHMGQQ-HMGRYPVHFHLCGDVDSKGGYSQPASVDGLSVHHSFSRCITVHGTSGLLIKDTIGFDTLGHCFFLEDGVEQRNILYHNLGLLTKPGTLLPTDRNSSMCTVMRDGVFGNYVPVPTTDCMAVSTFWIAHPNNHLINNAAAGSQDAGIWYLFHKEPTGESSGLQLLEKPELTPLGIFYNNRVHSNFKAGLFVDKGVKTTNASASDPREYLCLDNSARFRPHQDADPEKPRVAAIIDRLIAFKNNDNGAWVRGGDIIVQNSAFADNGKGLTFASDGSFPSDEGSSQEVTESLFVGESRNYGFQGGQNKYMGTGGIDQKPRTLPRNRTFPIRGFQIYDGPIHLTKSTFKKYVPTPDRYSSAIGFLMKNSWQTTPRNNVSLVKFGPQVSLNVFFGKPGPWFEDCELDGDKNSIFHDIDGSVTGYKDTYVGRMDNYLIRHPNCVNVTKWNAVICSGTYAQVYVQTWNTPNLSMIITRDEYPSHPMVLRGINQR-AISPQYQPVVMLEKGYTIHWNGPAPRTTFLYLVNFNKDDWIRVGLCYPANTSFQVTVGFLQRQNGSLSRIEDYEPARSMEELQKKPSERKFYFDSGTGLLFLYLRAHSHRDGHSYCSSQGCERVKIQAATDS---KDISNCMAKAYPQYYKKPSAVKRMPAMLTGLCQGCGTHQMVFTSDPHKSYLPVRFQSPGKAEIQRGD-PSIISVNGTDFTFRSAGALLLIVDACSVPFRVKEKRMFLSADVSHMEEYFKASIPPRSIVLLSTRGEIKQLN-ISDSLAVLGLAKPAHLYSKGSVVFLGFSGNFAPS---WTKLFTSPDEQGLGVLEQFLPLQMEEYGCS-RTGSVHRRDLDLLQQALKVL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9UHN6-1", "uniprot_id": "CEIP2_HUMAN", "id": "Q9UHN6-1", "name": "Cell surface hyaluronidase CEMIP2", "aln": "MYATDSRGHSPAFLQPQNGNSRHPSGYVPGKVVPLRPPPPPKSQASAKFTSIRREDRATFAFSPEEQQAQRESQKQKRHKNTFICFAITSFSFFIALAIILGISSKYAPDENCPDQNPRLRNWDPGQDSAKQVVIKEGDMLRLTSDATVHSIVIQDGGLLVFGDNKDGSRNITLRTHYILIQDGGALHIGAEKCRYKSKATITLYGKSDEGES--MPTFGKKFIGVEAGGTLELHGARKASWTLLARTLNSSGLPFGSYTFEKDFSRGLNVRVIDQDTAKILESERFDTHEYRNESRRLQEFLRFQDPGRIVAIAVGDSAAKSLLQGTIQMIQERLGSELIQGLGYRQAWALVGVIDGGSTSCNESVRNYENHSSGGKALAQREFYTVDGQKFSVTAYSEWIEGVSLSGFRVEVVDGVKLNLLDDVSSWKPGDQIVVASTDYSMYQAEEFTLLPCSECSHFQVKVKETPQFLHMGEIIDGVDMRAEVGILTRNIVIQGEVEDSCYAENQCQFFDYDTFGGHIMIMKNFTSVHLSYVELKHMGQQ-QMGRYPVHFHLCGDVDYKGGYRHATFVDGLSIHHSFSRCITVHGTNGLLIKDTIGFDTLGHCFFLEDGIEQRNTLFHNLGLLTKPGTLLPTDRNNSMCTTMRDKVFGNYIPVPATDCMAVSTFWIAHPNNNLINNAAAGSQDAGIWYLFHKEPTGESSGLQLLAKPELTPLGIFYNNRVHSNFKAGLFIDKGVKTTNSSAADPREYLCLDNSARFRPHQDANPEKPRVAALIDRLIAFKNNDNGAWVRGGDIIVQNSAFADNGIGLTFASDGSFPSDEGSSQEVSESLFVGESRNYGFQGGQNKYVGTGGIDQKPRTLPRNRTFPIRGFQIYDGPIHLTRSTFKKYVPTPDRYSSAIGFLMKNSWQITPRNNISLVKFGPHVSLNVFFGKPGPWFEDCEMDGDKNSIFHDIDGSVTGYKDAYVGRMDNYLIRHPSCVNVSKWNAVICSGTYAQVYVQTWSTQNLSMTITRDEYPSNPMVLRGINQK-AAFPQYQPVVMLEKGYTIHWNGPAPRTTFLYLVNFNKNDWIRVGLCYPSNTSFQVTFGYLQRQNGSLSKIEEYEPVHSLEELQRKQSERKFYFDSSTGLLFLYLKAKSHRHGHSYCSSQGCERVKIQAATDS---KDISNCMAKAYPQYYRKPSVVKRMPAMLTGLCQGCGTRQVVFTSDPHKSYLPVQFQSPDKAETQRGD-PSVISVNGTDFTFRSAGVLLLVVDPCSVPFRLTEKTVFPLADVSRIEEYLKTGIPPRSIVLLSTRGEIKQLN-ISHLLVPLGLAKPAHLYDKGSTIFLGFSGNFKPS---WTKLFTSPAGQGLGVLEQFIPLQLDEYGCP-RATTVRRRDLELLKQASKAH", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A3KPQ7-1", "uniprot_id": "CEIP2_DANRE", "id": "A3KPQ7-1", "name": "Cell surface hyaluronidase", "aln": "MQVNDGPSSHPIFVAPVNGNAQRSSGYVPGRIVPVRSPPPAKAPPPPPLKPPVPPPARPSVFNLSEDGNRREQAQNQQRKNTYICVGIFFGIFLLILILVLSLTSKDVLDENCPHQNPALRSWKPGHDLKKVVVIHSGEHYRLDSSATLYSITIQAGGSVVFADDKKGSKNITLRTRHILIEDGGALHIGAPKCRYRSLATITLVGRSDETAVTEVPGMGRKFLGVNSGGTLELHGSERMSWTFLTRTVPASGLATGDHAFQKNFSRGINLRVVDQDTAEVLVNERFDTHESQDDSKRLGELLKALPAGRIVALATGDSAVKNLVFETKQTIHDLLGSNYISDLKYRDAWALVSVIGGGNGSCTEDVREHENHDTGGKALARQDFFTVDGVGFTVTAYSEWSNGYPTTGFQVDAVDKVVLNLQDDVSSWNPGDRIVVASTDYSMYQAEEFTLLPCPNCNRKQVQIQGKPQFSHVGEILDGVDMRAEVALLSRNILIHGEMENSCYGGNWCQYFSYDTFGGHIKILGNFTSVHLSHIELKHMGQQREKGRYPLNFHRCGDVDQSGGYSNPAYVDSLSIHHSFSRCVTVHATNGLLVKDTVGYDTLGHCFFLKDGIEQRNIFFHNLGLLTRPGTILPTDRNDSMCTEITDRVYKGYIPIPANECKAVSSFWIAHPNNHLISNSAAGSQDAGIWYVFHNSSTGDSHGMISETKAELTPLGTFFNNRVHSNFKAGLFIDRKVKSTNATAADPREYLCLDNSARFRPHESSDPSRPRVAAIIDTLISFKNNDLGAWIRGGDIIIRN------------SGDGSYPKDEGSSQEVSQSLFIGESRNRGTNGGQNKYWGIGGVDGKMRTLPRNKTFPIRGFQINDGPVRIFDSTFRAFSPTADRFTMAVGFSLKNIWQLTPRNNLSALAFHPSVTLRAFFGRPGDWFEQNDLDGDKNSIFHDLDGSISGYADTYVARADNFLIRHPQCVDMPQWNGVVCSGKYSQVYIQTQAASNLSLSISRDEYPDKPMVLRGIRTKTSPSQQYQPVLMMGKSYTMHWNGPAPRETVLSLINFDQDDWALLGLCYPNETVFQITSDIYNKQNNGFEGIEDYGPVTSIADLEKRQQERKYFFDKSAGLLWLYARARHRRDGNSYCSSAGCERVKIIATIRANQKTETCNCTANAYPKYSKPASNIVPMPKPNTEPCGACGASQFAFSSDPWNSYLQTQIKSLSVKEEQDNDTQAYITVNAQRFDLSQSGFLLVTVDACSG--KVTKNSMFSSLDT-KMEQFFKTGIMKRSIVLLATRGQPASFAGVAQYLESLGSAKTPDLQNKVAIAFFGFLGQGGPSPQPWSTLLTCQGAKILGLQERFIPLSLEEYSCPPKKDSPTRMDLELLKKIS---", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* . .. . * *: * ***.::..*****::**.*..**.* ... :.. . .*. .*: *. :.:::***:**..* *:: * ::*.::** . *****.*** **.*.**:* * :**:.*: ** *.**: **.** ** :**.*:*.**:******::***:********* ****:* ***** *:*** :* :*:**:**::********:.: ***:*:**: :***. *.::*:*:****:*:**:*****.:* *:***** :::*:** *:*: .*****:*.****.*.*: * * *:: ***: *..* **:*****.**.**. **.*.**::***.:******: :*:*:** *:******* :* . :**:*: .* * *:* ****:* .**:***************:*** *.:*.: **::: **: *:***:**:******.:*:***:*:** *:***. * **:*.*******: * ********::******** . ****::** ***** .*** .: *:.**:*******:***.:.***:***:*:*********:**:**** ::*******:***:******.**** : * *: .*:*:*:.:* ***:********:**.*:***********:**:..**:* *: *.****** *:*************:*: **:**::*:*****************:.::*.:*****:** **:***** ***:******::* :.***:*.********::***:***:* * :****** * **:* * ******:********* ***::: ***: : **.**:: *:** :** ** *****:* : * * *:*..***:** ***: ::**********:***::** *:**.* **:*****.**.:.:**.*:***.*:***:** : ***: *:*****.:*******. : : *****:*: *.**:**.***** *.* *:**:::** :***** :* **:* . ::**..:. **:* *. *: :*::: .***::**..:***:** :*: :*.*:***** ******* *: : .: .** *:***:* : .* : ** * * .**: *..*:*** :*** .:::* . * * .: : *:**. * : .:* :*: **.** ::.:: :* * ::*:::*:.* ******:***: .: ::. : ** **...* .* : *:** *: ** *: *:*. : **: *:::**.::**.*. : : * **:**:: ", "identical_positions": 751, "similar_positions": 387, "identity": "53.8%" }, { "cls_id": "homologset.agr.MGI:1890378", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q4V8E9-1", "uniprot_id": "NRIF1_RAT", "id": "Q4V8E9-1", "name": "Neurotrophin receptor-interacting factor 1", "aln": "MASTLPTTWPHESVKFEDVSLTFTKEEWAQLDLQQKCLYREIMMENYNNMISVEHHFSKPNVISQLEEAEDCWPMEREIRQDILPECSGPSLDPGMNSFPAESPLMKIKVVEVLTLNKDVAGPRNALIQSLYPESRENLNPGNLKPAK-PSKRLTDTEALRQKFRHFQYEESAGPQKAVSRLRKLCHQWLQPNIRSKKQIIELLVFEQFLSALPEKFRVWLESQHPEDCRAAVALLENMTSVTKDDAQLV--------CSSEATDQLKEKRKDVATLPVT----VPPEEPVTFQDVAVGFSQEEWRLLGPVQRTEYHDVMLETLGNLVSVGWEPTLENRAISPDSPIPVVKPIHDPNPKDLSRNGIQSTVFEIISQDRVQEIHTIESNQAGLLQEKSHPQKKLSESSKSQEGTNLHKSQGSLDEVPPRKHVKVKQKGTRKGKDRKNTISMTRGLRIRNQQKDSVEWQGRGDSNPMTHGYSIKNQR-GSEQGTAGARRDPITLTVSAQFYQKATGSEEGRFRDNSNAIVPDTPTKIHQKSPEWHKVGRSNNSMS---SVQNDQMGSGAGRGRDNTILTHALPVKIHQKGYEEGKVQGNRNSLRHVKAHQKGSKGERVRELSTSEKHVPYIKNHLKTSEREKGRENNDSIKYGPYIKTCYRGSEVRKLRRANNCTKAISRHAQQIFFIKIHKGSQVCRCSECGKMFRNSRYFSVHKKIHTGERPYMCMACGKAFVQSSSLTQHLRIHSGERPFECSECGRTFNDRSAISQHLRTHTGAKPYHCQHCGKAFRQSSHLTRHERTHTGERPYVCSNCGKAFTQSSHLIGHQKTHR--IKFKKQPKL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q923B3-1", "uniprot_id": "NRIF1_MOUSE", "id": "Q923B3-1", "name": "Neurotrophin receptor-interacting factor 1", "aln": "MASTLPTTWPHESVKFEDVSLTFTEEEWAQLDFQQKCLYREIMMENYSNMISVEHHFSKPNVISQLEKAEDCWPMQREIPQDTLPECSWPSPDPGMNSFPSKSPLMKIEVVEVLTLNKDVAGPRNALIQSLYP---EDLNPGNLKPAQQPSKRLTDTEASRQKFRHFQYEESAGPQKAMSQLRKLCHQWLQPNTRSKKQILELLVLEQFLNALPEKFRVWVESQHPEDCKAVVALLENMTSVSKDDASLA--------CSSEATDQLKEKRKGVATLPVTFAAEVPAEEPVTFQDVAVDFNEEEWRLLGPTQKTEYHDVMLETLGNLVSVGWEPTLGNRELTPDSPIPVVKPIHDPNTNDLSRNGTQSTVFESILEDGVKEMHSIESNQVGNLQEKGHPQKKFSESSKSQDQTSRHKSQGSLNEVLPRKYVKVKQKGTGKRKGRTNTISMTRGLRIRKQQKDSVEWQGRSGSTPVTHGSSIKKQQQGSEQGKPGTSRDPITLTVPAKVYQKATGSEESIFMDSSDAMVPDVPPKIHQKGPEWHKVGESNNSMLQGSSVQNHQMESGAGRASDNSLLTHALPVKSHQKGYKEGNVQGNRNSWKHIKPHQKGSKGERVEELSTSEKHVPYVKNHLKTSERGKDREINASIKCDPYIKTYYRGSDVGRLRRANNCRKAFSLHAQQISFIKIHKGSQVCRCSECGKLFRNARYFSVHKKIHTGERPYMCMACGKAFVQSSSLTQHLRIHSGERPFECSECGRTFNDRSAISQHLRTHTGAKPYHCERCGKAFRQSSHLTRHERTHTGERPYVCIKCGKAFTQSSHLIGHQKTHG--IKFKKQPKL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q96GC6-1", "uniprot_id": "ZN274_HUMAN", "id": "Q96GC6-1", "name": "Neurotrophin receptor-interacting factor homolog", "aln": "MASRLPTAWSCEPVTFEDVTLGFTPEEWGLLDLKQKSLYREVMLENYRNLVSVEHQLSKPDVVSQLEEAEDFWPVERGIPQDTIPEYPELQLDPKLDPLPAESPLMNIEVVEVLTLNQEVAGPRNAQIQALYAEDGSLSADAPSEQVQQQGKHPGDPEAARQRFRQFRYKDMTGPREALDQLRELCHQWLQPKARSKEQILELLVLEQFLGALPVKLRTWVESQHPENCQEVVALVEGVTWMSEEEVLPAGQPAEGTTCCLEVTAQQEEKQEDAAICPVT----VLPEEPVTFQDVAVDFSREEWGLLGPTQRTEYRDVMLETFGHLVSVGWETTLENKELAPNSDIPEEEPAPSLKVQESSRDCALSSTLEDTLQGGVQEVQDTVLKQMESAQEKDLPQKKHFDNRESQANS------GALD---------------------TNQVSLQK---------------------------------------------------------------------------------------------------------IDNPESQANSGALDTNQVLLHKIPPRKRLR--------------------KRDSQ-------VKSMKHNSRVKIHQKSCERQKAKE-------------------------GNGCRKTFSRSTKQITFIRIHKGSQVCRCSECGKIFRNPRYFSVHKKIHTGERPYVCQDCGKGFVQSSSLTQHQRVHSGERPFECQECGRTFNDRSAISQHLRTHTGAKPYKCQDCGKAFRQSSHLIRHQRTHTGERPYACNKCGKAFTQSSHLIGHQRTHNRTKRKKKQPTS", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*** ***:*. *.*.****:* ** ***. **::**.****:*:*** *::****::***:*:****:*** **::* * ** :** . . ** ::.:*::****:*:********::******* **:**. . . : .: .*: *.** **:**:*:*:: :**::*:.:**:********: ***:**:****:****.*** *:*.*:******:*: .***:*.:* :::::. . *. *.* * :**::..* *** * .***********.*..*** ****.*:***:******:*:*******.** *: ::*:* ** :* . : :: **: *:.:* :. *:*:: :* ***. **** :. :** : *:*: .* :*: : ::* : :.:* * :* * :* : : : ::.*: .* ** . :* * *:.** * :* .*.* *::* ::** **:***************:***.****************:* ***.********** *:*********.*************************:*: *********** **:*********.* :***************:** : ****. ", "identical_positions": 365, "similar_positions": 165, "identity": "43.4%" }, { "cls_id": "homologset.agr.MGI:1890380", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8VCX6-1", "uniprot_id": "KPTN_MOUSE", "id": "Q8VCX6-1", "name": "KICSTOR complex protein kaptin", "aln": "-MGEAAVAEGPCPLLEDSFTRFSSQSNVYGLAGGADGRGELLAATLKGKVLGFRYQDLRQKIRPVAKELQFNYIPVDAEIVSIDTFNKSPPKRGLVVGITFIKDSGDKGSPFLNIYCDYEPGSEYNLDSIAESCLNLELQFTPFQLCHAEVQVGDQLETVFLLSGNDPAIHLYKENEGLHQFEEQPVENLFPELTNLTSSVLWLDVHNLPGSSQRLSALGCQSGYVRVAHVDQKNQEILQTWTIQQDGPISRVIVFSLSASEATQDSPQQEGYSLLVASMLEPAVVYWDLLNKGLDDQLLLPGSDQFDSVLCGLVTDVDLDGQLEVLVATYGQELLCYKYRG----LPEDSRGFRLLWRRSFASPLLAMAHVDLTGDGLRELAVISLKGVHILQHSLIQASELVLTRLRHQVEQRK-HQQGLGDRVGPRPVEHPAS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9Y664-1", "uniprot_id": "KPTN_HUMAN", "id": "Q9Y664-1", "name": "KICSTOR complex protein kaptin", "aln": "MMGEAAVAAGPCPLREDSFTRFSSQSNVYGLAGGAGGRGELLAATLKGKVLGFRYQDLRQKIRPVAKELQFNYIPVDAEIVSIDTFNKSPPKRGLVVGITFIKDSGDKGSPFLNIYCDYEPGSEYNLDSIAQSCLNLELQFTPFQLCHAEVQVGDQLETVFLLSGNDPAIHLYKENEGLHQFEEQPVENLFPELTNLTSSVLWLDVHNFPGTSRRLSALGCQSGYVRVAHVDQRSREVLQMWSVLQDGPISRVIVFSLSAAKETKDRPLQDEYSVLVASMLEPAVVYRDLLNRGLEDQLLLPGSDQFDSVLCSLVTDVDLDGRPEVLVATYGQELLCYKYRGPESGLPEAQHGFHLLWQRSFSSPLLAMAHVDLTGDGLQELAVVSLKGVHILQHSLIQASELVLTRLRHQVEQRRRRLQGLEDGAGAGPAENAAS", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ******* ***** ********************.***********************************************************************************************:****************************************************************************:**:*:*******************:.:*:** *:: ***************:: *:* * *: **:************ ****:**:****************.*********: ****************** *** .:**:***:***:****************:****:******************************: : *** * .*. *.*:.**", "identical_positions": 381, "similar_positions": 34, "identity": "87.39%" }, { "cls_id": "homologset.agr.MGI:1890386", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9QXW4-1", "uniprot_id": "FSCN3_MOUSE", "id": "Q9QXW4-1", "name": "Fascin-3", "aln": "MAEVDWIHRHPKAEDLRVGLISWAGTYLTFEAYKSSVTASAKSLGRRQTWELLVSNEHESQAVIRLKSLQGLYLLCEADGTVCYGRPRTSHHGCFLLRFHRNGKWTLQCIISGRYLESDGEDVFCNSRVLSAYHMWTPRPALHVHVILYSPIYHSYARADHTVGRIWVDAAIPCLEECGFLLHFQDGCYHLETSTHHFLSRVDRLVPQRSSQTAFHMQVRPRGLVALCDGEGGTLYPQGSHLLLGMGSAPMKGEEWFVLQHFPTWVSLKSKSRRFLSVIYDAEVCAASERLTQMSLFQYECDSETPTLQLRSANGYYLAQRRHRAIIADGHPMESDTFFRVHWNCGKITLQSPNGRFLGIASDGLLMANVTIPGPNEELGIRFANRPFLVLRGRYGYVGSSSDHDLLKCNMDQPDCIQLLPCRQGIYHFQAQGGSFWSITSFGTFRPWGKFALNFCIELQGSSLLTVLAPNGFYLRADRSGTLLADSEEITKECIWEF", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "F7FMC7-1", "uniprot_id": "F7FMC7_RAT", "id": "F7FMC7-1", "name": "Fascin", "aln": "MAEVDWIHRHPKAEALRVGLISWAGTYLTFEAYKSTVTATAKSLGRRQTWELLVSNEHETQAVVRLKSLQGLYLLCEADGTVCYGKPRTSHHGCFLLRFHRNGKWTLQCIISGRYLESDGQDVFCNSRVLSAYHMWTPRPALHVHVILYSPTYHSYARADHTVGRVWVDAAVPCLEECGFLLHFQDGCYHLETSTHHFLSRVDRLVPKRSTQTAFHMQVRPRGLVALCDGEGGSLYPQGSHLLLGLGSTPMKGEEWFVLQHFPAWVSLKSKSRRFLSVIYDAEVCAASERLTQMSLFQYECDSESPILQLRSANGFYLAQRRHRAIIADGHPMESDTFFRVHWNCGKITLQSPNGRFLSIASNGLLMSNVTIPGPNEELGIRFANRPFLVLRGRYGYVGSSSDHDLLKCNMDQPDCIQLLPCHQGIYHFQG----------------WILLVNNILWHLP---PLGKICPQLLYRTSGEQLAYGAGTQWLLPPS----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9NQT6-1", "uniprot_id": "FSCN3_HUMAN", "id": "Q9NQT6-1", "name": "Fascin-3", "aln": "MDETEWIHRHPKAEDLRVGLISWAGTYLTFEACKNTVTATAKSLGRRQTWEILVSNEHETQAVVRLKSVQGLYLLCECDGTVCYGRPRTSHHGCFLLRFHRNSKWTLQCLISGRYLESNGKDVFCTSHVLSAYHMWTPRPALHVHVILYSPIHRCYARADPTMGRIWVDAAVPCLEECGFLLHFRDGCYHLETSTHHFLSHVDRLFSQPSSQTAFHMQVRPGGLVALCDGEGGMLYPQGTHLLLGMGCNPMRGEEWFILQHCPTWVSLRSKTGRFISVIYDGEVRAASERLNRMSLFQFECDSESPTVQLRSANGYYLSQRRHRAVMADGHPLESDTFFRMHWNCGRIILQSCRGRFLGIAPNSLLMANVILPGPNEEFGILFANRSFLVLRGRYGYVGSSSGHDLIQCNQDQPDRIHLLPCRPGIYHFQAQGGSFWSITSFGTFRPWGKFALNFCIELQGSNLLTVLAPNGFYMRADQSGTLLADSEDITRECIWEF", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* *.:********* ***************** *.:***:***********:*******:***:****:********.*******:****************.******:********:*:****.*:*********************** ::.***** *:**:*****:************:***************:****..: *:********** *********** *****:*****:*. **:*****:*** *:****:**: **:*****.** ******.:*****:*****:* :*******:**:******::*****:*******:*****:* *** .****.**.:.***:** :******:** ****.***************.***::** **** *:****: ******. * :. *: .* * :.*: :* :... : *.:: : . ", "identical_positions": 352, "similar_positions": 84, "identity": "70.68%" }, { "cls_id": "homologset.agr.MGI:1890391", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9EQC7-1", "uniprot_id": "FSTL3_MOUSE", "id": "Q9EQC7-1", "name": "Follistatin-related protein 3", "aln": "MRSGA---LWPLLWGALVWTVGSVGAVMGSEDSVPGGVCWLQQGREATCSLVLKTRVSREECCASGNINTAWSNFTHPGNKISLLGFLGLVHCLPCKDSCDGVECGPGKACRMLGGRPHCECVPNCEGLPAGFQVCGSDGATYRDECELRTARCRGHPDLRVMYRGRCQKSCAQVVCPRPQSCLVDQTGSAHCVVCRAAPCPVPSNPGQELCGNNNVTYISSCHLRQATCFLGRSIGVRHPGICTGGPKVP-----AEEEENFV", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q99PW7-1", "uniprot_id": "FSTL3_RAT", "id": "Q99PW7-1", "name": "Follistatin-related protein 3", "aln": "MRPGA---LWPLLWGALVWAVGSVGAVMGSGDSVPGGVCWLQQGKEATCSLVLKTQVSREECCASGNINTAWSNFTHPGNKISLLGFLGLVHCLPCKDSCDGVECGPGKACRMLGGRPHCECVSNCEGVPAGFQVCGSDGATYRDECELRTARCRGHPDLRVMYRGRCQKSCAQVVCPRPQSCLVDQTGSAHCVVCRAAPCPVPPNPGQELCGNNNVTYISSCHLRQATCFLGRSIGVRHPGICTGGPKVP-----AEEEENFV", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O95633-1", "uniprot_id": "FSTL3_HUMAN", "id": "O95633-1", "name": "Follistatin-related protein 3", "aln": "MRPGAPGPLWPLPWGALAWAVGFVSS-MGSGNPAPGGVCWLQQGQEATCSLVLQTDVTRAECCASGNIDTAWSNLTHPGNKINLLGFLGLVHCLPCKDSCDGVECGPGKACRMLGGRPRCECAPDCSGLPARLQVCGSDGATYRDECELRAARCRGHPDLSVMYRGRCRKSCEHVVCPRPQSCVVDQTGSAHCVVCRAAPCPVPSSPGQELCGNNNVTYISSCHMRQATCFLGRSIGVRHAGSCAGTPEEPPGGESAEEEENFV", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "**.** **** ****.*:** *.: *** :..**********:********:* *:* ********:*****:*******.***********************************:***..:*.*:** :*****************:********* *******:*** :*********:********************..******************:***************.* *:* *: * ********", "identical_positions": 213, "similar_positions": 31, "identity": "80.68%" }, { "cls_id": "homologset.agr.MGI:1890393", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I5ZM30-1", "uniprot_id": "A0A8I5ZM30_RAT", "id": "A0A8I5ZM30-1", "name": "", "aln": "MAAPEAQGLGVDPREDRVRGVRGGIGHIDHEAHLGSFQVLAIINKACMNIMELVSLLYVGASFGYMPRSGIISGSSGSTISNFLRNLQTDFQNDCTSLQSHQQWRSVPFSPHLCQHLSSPEFFISAILTGVRWNLRVVLMCISVMTVDVEHFFRYFLASRYSSDSKDWILESLSLPERPGGTAALEGP--PSVPCIFCEEHFPMTE-QDKLLKHMIIEHKIVIADVKLVADFQRYILYWRKRFTEQPITDFCSVIRINSTAP--FEEQDNYFLLCDVLPEDRILREELQKQKLKEILDQQQRERNDTNFHGVCMFCNEEFRGNRSVLLNHMAREHAFNIGLPDNIVNCTEFLCTLQKKLDNLQCLYCEKTFRDKNTLKDHMRKKQHRRINPKNREYDRFYVINYLELGKSWEEVQLEDDRELLDLQ----------------------------EDDWSDWQEY--PVSAVCLFCEKQEETIDKLYVHMKDTHEFDLLRIKSELGLNFYQQVKLVNFIRRQVHQCKCYSCQAKFKSKAELRTHMENAKHTSLLPDSKTWDQLEYYFPTYENDTLLCTLSDSESDLTAQEQTENVPIISEDTSRLCALRQSSVLNQLLLQECLEN", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "E9Q6D6-1", "uniprot_id": "ZN277_MOUSE", "id": "E9Q6D6-1", "name": "Zinc finger protein 277", "aln": "MAASEVQGLPVDPREAGVRGVRGGIGHTDHEGHLGSFQLLATINKAAMNIVEHVSFLPVGTS------SGYIAASSGITMSNFLRNRQTDFQSGCTSLQSHQQWRSVPLSPHPHQHLLSPEFLILAILTGVRWNLRIALICISLMIKDAEHFFRCFSAIWYSSDSKDCILEPLSLPESPGGTTALEGS--PSVPCIFCEEHFPMAE-QDKLLKHMIIEHKIVIADVKLVADFRRYILYWRKRFTEQPITDFCSVIRINSTAP--FEEQDNYYLLCDALPEDRILREELQKHKLKEVLDQQQRERNDTSFHGVCMFCSEEFRGNRSVLLNHMAREHAFNIGLPDNIVNCAEFLCTLQKKLDNLQCLYCEKTFRDKNTLKDHMRKKQHRRINPKNREYDRFYVINYLELGKSWEEVQSEDDRELLDLQ----------------------------EDDWSDWQEY--PVSAVCLFCEKQEETIDKLYVHMKDTHEFDLLRIKSELGLNFYQQVKLVNFIRRQVHQCKCYSCHVKFKSKADLRTHMEDTKHTSLLPDRKTWDQLEYYFPTYENDTLLCTLSDSESDLTAQEQTENVPVISEDTSRLCALKQSSVLNQLLLQGCLEN", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9NRM2-1", "uniprot_id": "ZN277_HUMAN", "id": "Q9NRM2-1", "name": "Zinc finger protein 277", "aln": "MAASKTQGAVAR--------------------------------------------------------------------------MQEDRDGSCSTVG------------------------------GVGY-----------------------------GDSKDCILEPLSLPESPGGTTTLEGS--PSVPCIFCEEHFPVAE-QDKLLKHMIIEHKIVIADVKLVADFQRYILYWRKRFTEQPITDFCSVIRINSTAP--FEEQENYFLLCDVLPEDRILREELQKQRLREILEQQQQERNDTNFHGVCMFCNEEFLGNRSVILNHMAREHAFNIGLPDNIVNCNEFLCTLQKKLDNLQCLYCEKTFRDKNTLKDHMRKKQHRKINPKNREYDRFYVINYLELGKSWEEVQLEDDRELLDHQ----------------------------EDDWSDWEEH--PASAVCLFCEKQAETIEKLYVHMEDAHEFDLLKIKSELGLNFYQQVKLVNFIRRQVHQCRCYGCHVKFKSKADLRTHMEETKHTSLLPDRKTWDQLEYYFPTYENDTLLCTLSDSESDLTAQEQNENVPIISEDTSKLYALKQSSILNQLLL------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9W1V7-1", "uniprot_id": "ZN277_DROME", "id": "Q9W1V7-1", "name": "Zinc finger protein 277", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------MEHEVAVSGGDSSLEEITGSSKLKPSKNTAIKCLKCDKVYIFPSDKDDCLAHLYMEHRLVIADVEDIALLEDYLQYWEKEFHTHEFEQYCTTMFLDQLPDGKYAKNEKYYLLCDILPQDYELRRRLKEKRLSEALERHQFELTDRTFSKECLFCRAIIKGLRADYLDHLFDKHFLLVGKPEKLVYVDELLDHLEENLNRLMCLYCEKIFRDRPTLKEHMRKKGHKRINPNRREYDKYFLINYNRVPTAPTPRKQHLQKRRRETASVSTVADPETGSVDFDKHFARPDSDGEHDSDWSDWAADGEPSSIKCLFCHHLGDNFTALKKHMHEVHRLDFEKATSSL--NFYQRVKVVNYLRRQMCLLRCVTCDLQFDEEELLVEHMAQESHHGIG-DKESWDKPEFFFPYIENDGLLCVLDDSGGDDPDVDTVRIISEDSLAQINKDAERLSLENFKLL-------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : : * * *:: *: . .:: *: *:: : ... :*. * *: :**::*****: :* :. *: **.*.* : : ::*:.: ::. . : ::::*:**** **:* **..*::::* * *:::* * .* .* *:** : * *: *:*: :* : :* *:::* *:* *:::*:.* ****** ***: ***:***** *::***:.****::::*** .: .: : . ::. : :.***** * * ****.: :.: * **.:.*.:*: : .*.* ****:**:**::***: :* *. :*..: * ** : .* .: * ::**: *::** *** ***.*.** .* . : . :. * . * : * :** ", "identical_positions": 142, "similar_positions": 143, "identity": "22.76%" }, { "cls_id": "homologset.agr.MGI:1890394", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3Z908-1", "uniprot_id": "D3Z908_RAT", "id": "D3Z908-1", "name": "", "aln": "---------MKTLRARFKKTEG-----------------------------QDWGKSDQRLLQAVENNDVARVASLIAHKGLVPTKLDPEGKSAFHLAAMRGSAGCLEVMLAQGADVMSTDGAGYNALHLAAKYGHPECLKQLLEASCMVDVEDSSGWTALHHAAAGGCLSCSKLLCSFKAHMKPRDRSGATPLIIAAQMCHTDLCRLLLQQGAAANDQDLQGRTALMLACEGGSPETVEVLLQGGAQLGITDALGQDATHYGALTGDKLILQLLQ-------------ESAQRPSPPNASLEDDSGEASSQNSASSHEKRGAHKKRKAPQPPATTPIPDDQDAYEEIVRLRQERGRLLQKIRGLEQHTEQRRRREPLEAEASSVHSLERQVQELQQMLAEKQEEKESLGREVESLQSRLSLLESERGNTSYE---------EEGEMPDFPGAEALLSKN---------------PSPSGEEIVASLQEQVAQLTRQNQELLEKVQILEEFEKDEAQLVEESQPEVVPLVLYESLRAELQQLQRQHTEAMHMLQLQQ-GEPSGTHGGEETAYQEIKDKGITIQNGLGVQDLNGTTYTEATANEMEPQAGGSKGVGNTEAGASEAALIEPEAVGSEAKGK-----DGVAAEAMDTSVTIAEA-LNVKSVGDNAEREPVTAEDTGGKENPGMKADGVDVL-------QAGLTGTVTRNMEATGVRDTGIQATGVEATAVKTTGVQATVAEVIG--VKVTGVQTTAAEAIGVNNTTAEATEAEATGAQANCSKATEADSTGAQDTAMEPTRAQATVLDTTEAETNGTEDHCAAILHPGAAAAALQA-ELESRIRALEEALRRREQEAAAELEAARG--RFAQAEAEAEEAARGRSRELEALRELLATATATGERARTEAAELRQQLAASEARVAELSSAQDAARE-------------------------------------------------------ELERMRGASVPADEHEHALDALRDHVARLQAQLADLARRHEKTSAEVFQ--------------------------------------------------------ITDLSKEVFTLKEALKVQQSTPASSKEQ--------EEALRGQVTALQQQIQEEAQEHCTVVALYRTHLLYAIQGQMDEDVQCILSQILQMQRLQAQGR", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q80VM7-1", "uniprot_id": "ANR24_MOUSE", "id": "Q80VM7-1", "name": "Ankyrin repeat domain-containing protein 24", "aln": "---------MKTLRARFKKTEG-----------------------------QDWGKSDQRLLQAVENNDVARVASLIAHKGLVPTKLDPEGKSAFHLAAMRGAAGCLEVMLAQGADVMSTDGAGYNALHLAAKYGHPECLKQLLEASCVVDIEDSSGWTALHHAAAGGCLSCSKLLCSFKAHMNPRDRSGATPLIIAAQMCHTDLCRLLLQQGAATNDQDLQGRTALMLACEGGSPETVEVLLQGGAQLSITDALGQDATHYGALTGDKLILQLLH-------------ESARRSSPPSASLEEDSGEASSQNSVSSHEKQGAPKKRKAPQPPASTPVPDDRDAYEEIVRLRQERGRLLQKIRGLEQHKE-RRRKEPLEAEASSVHSLERQVQELQQMLAEKQEEKESLGREVESLQSRLSLLENERENTSYDVATLQD---EEGEMPDFPGADALMPKN---------------QSPSAEEIVASLQEQVAQLTRQNQELLEKVQILEEFEKDEAQMAEESQAEVVPLVLYESLRAELEQLRRQYTEAMHSQQQQQEGEPPRAQEGEETAYQEIKDKGITIQNGPSVPDLNGTTYAETKANGMELQAGGSKGVWNTEAGVSEAAPIEPEAAGSEATGK-----DRLAAKEMDTSATMAEA-LNVKALGDNAESEPVAAEDTGGKENPGMKADEVDVLA------QAGLTGTVIRNMEAIGVRDTGIQATGLEAKAVKTTGVQATVAEVIG--VKVTGVQTTAIEAIGVKDTTQVA-----TGAQADCWQATEADCTGAQDTAMEPTGAQATVTETTEAETSGTEDPCAAILHPGAAAAALQA-ELETRIRGLEEALRRREREAAAELEAARG--RFA----EAEEAARGRSRELEALRELLATATATGERARTEAAELRQALAASEARVAELSSTVDAARE-------------------------------------------------------ELERMRGASVPADEHEHALSALRDHVTRLQAQLADLARRHEKTSAEVFQ--------------------------------------------------------ITDLSKEVFTLKEALKVQQSTPASSKE---------EEALRGQVTALQQQIQEEAREHGAVVALYRTHLLYAIQGQMDEDVQCILSQILQMQRLQAQGR", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8TF21-1", "uniprot_id": "ANR24_HUMAN", "id": "Q8TF21-1", "name": "Ankyrin repeat domain-containing protein 24", "aln": "---------MKTLRARFKKTELRLSPTDLGSCPPCGPCPIPKPAARGRRQSQDWGKSDERLLQAVENNDAPRVAALIARKGLVPTKLDPEGKSAFHLAAMRGAASCLEVMIAHGSNVMSADGAGYNALHLAAKYGHPQCLKQLLQASCVVDVVDSSGWTALHHAAAGGCLSCSEVLCSFKAHLNPQDRSGATPLIIAAQMCHTDLCRLLLQQGAAANDQDLQGRTALMLACEGASPETVEVLLQGGAQPGITDALGQDAAHYGALAGDKLILHLLQ-------------EAAQRPSPPSALTEDDSGEASSQNSMSSHGKQGAPKKRKAPPPPASIPMPDDRDAYEEIVRLRQERGRLLQKIRGLEQHKE-RRQQE--SPEASSLHILERQVQELQQLLVERQEEKESLGREVESLQSRLSLLENERENTSYDVTTLQD---EEGELPDLPGAEVLLSRQ---------------LSPSAQEHLASLQEQVAVLTRQNQELMEKVQILENFEKDETQMEVEALAEVIPLALYDSLRAEFDQLRRQHAEALQALRQQETREVPRE-EGAACGESEVAG-ATATKNGPTHMELNGSVAPETKVNGAETIDEEAAGDETMEARTMEAEATGAEATGAEATGAKVTETKPTGAEVREMETTEEEANMETKPTGAQATDTETTGVEAMGVEATKTKAEEAEMQAYGVGAGQAEPPVTGTTNMEATGSRATGMESTGVSATGVENPGVEATVPGISAGPILHPGAAEASEKLQVELETRIRGLEEALRQREREAAAELEAALGKCEAAEAEAGRLRERVREAEGSGASGGGGGDTTQLRAALEQAREDLRDRDSRLRELEAASACLDEARASRLLAEEEARGLRAELAQREEARLEQSRELEVLREQLATARATGEQQRTAAAELGRARDAAEARVAELPAACEEARQGLAELREASEALRQSVVPASEHRRLQEEALELRGRAASLEQEVVATGKEAARLRAELERERVCSVALSEHERIVGTLQANVAQLEGQLEELGRRHEKTSAEVFQVQREALFMKSERHAAEAQLATAEQQLRGLRTEAERARQAQSRAQEALDKAKEKDKKITELSKEVFNLKEALKEQPAALATPEV----------EALRDQVKDLQQQLQEAARDHSSVVALYRSHLLYAIQGQMDEDVQRILSQILQMQRLQAQGR", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9PSG1-1", "uniprot_id": "A0A8M9PSG1_DANRE", "id": "A0A8M9PSG1-1", "name": "", "aln": "MDPHVVFNPMKHFCMCYGVITS-----------------------------QDWSKTDDRLLQAVEQNDPEKVATLLVKKGLCPSKLDAEGKSAFHLCASRGRLDCLEVILSHGVDIGVTDGTGFNALHLAAKNGQPDCLKRLLQERMPVDSTDSFGRTSLHHAAVSGCLSCTEILWDFKANLDAQDGDGSTPLILAAQMSRIELCAFLLERGANPNLQDNQGRSALMFSCESDSMETVEMLLKGGTNPHLTDALGHNSTHYSITAGNHSITQLLQNLGVTTAAEGSSEEQAPPPNPPSSGTTPRKRKAPPPPKSPAQGLPPSSEASNTPPSPVFTQSPESQSPAPPSPAPRTQHPPSENLTEDEEVFEEIRKLRLERGRLLQKIKVLEQQQSSATTALEELSSLKERLSEAEAERDRLLVELEELRAAQVSGVTCDSEDAEDSDDMLDFPGAEKLLSRQSRGLDANLPAEQGEGISQENPAMVEQLRRKVEELTSQNADLVLKVQMLEMFEKDDTDMQ-SSGPDFVPTAQYESLRREFEELQEKYSRAQASTEASSIAEDPGCEEKEEKHQKALEKKLSQAQAELEELKEQMRLGVYSVEDAEEKPEKSSVEGGDLETHQLKARVEELEAELVSKKTD-------GEGLSEDDNNTMQQLKERVKELEAALQDREKEGEENETVVNLKKQVEELGKALELS--KAAGKKEGEGAPLNGLQARVEELEQELKESVPRGQFEEVQVTLGLQLNQLAQERAEVAARLNQALLELERLRPPSHIDEDEEDDEPSESSEVSIASDHSLHMSPGGRTLEAIKEELEVAR--QEAAQALDSLCAERESRAQDVLQLRDAVPLVKHQESLSAVAQQLAQTEKELQAERALREHAQTELSRLEIELKAAQKDSVSKEEHDKIKADLERSLEDSRQIAAAAQESLSKKETELKDLR--------------------------------------------------SQKALEQGLVSKEDHEAQRLSLQAEINTLTAQLADLARKHEKTCLEVFQVQREALFNKSERQVAESQLETVKKQLTDLQAESTHIQQLHQDIQHSQGLIKEKDRKITELSKEVFRLKEALGALTPPLGRSPSPPSSGIPGQQLALQNRVTSLTQQLQDWERKHKAVVSIYRSHLLAAVQGRMDEEVQALLLQILRMTQKGQN--", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ** : : ***.*:*:*******:** :**:*:.:*** *:***.********.* ** .****::::* :: :**:*:******** *:*:***:**: ** ** * *:*****..*****:::* .***::..:* .*:****:****.: :** :**::** .* ** ***:***::**. * ****:**:**:: :*****::::**. :*:: * :**: * * ..**.: . :*.. . .:: : : ::* .*. *:.:.. * :: : .. * . * *: : ..:: **:* .. * * .. ** *.. . : * **. * :..:: *:***: *:.:: * . : .*:.:* ** ** :*: ***:** ****:::: .: .:.:* . *:*** *:::*:.:::.* . .. * . . : : . : : : * : *: :* ** . . . : . * : ..* . : :.: * ::. * :: .: .. : : . :: : : : .: .. . : . :: . . : ::* : * . : *.* ** *: : :. *: : * : : .* : . : . : . *. .:** :*: .: * .** :*.*:****. **** **:****** ***** .. . . **:.:*. * **:*: :.* :**::**:*** *:**:***:** :* ***:* : : ", "identical_positions": 259, "similar_positions": 268, "identity": "21.57%" }, { "cls_id": "homologset.agr.MGI:1890396", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0ABK0LW82-1", "uniprot_id": "A0ABK0LW82_RAT", "id": "A0ABK0LW82-1", "name": "Histone-lysine N-methyltransferase", "aln": "MAAARAKARSGEARARCHRAPGPPQRPKPRRTTRRCRADTVTARRSRSSAGGRRAGSNRARSRAPRAAVFGGECARGASFKEFSGLCMLKIYFPMRKINEAKISAVFQNGKAWCVPCLVSLDTLQELCRKEKLTCKSIGITKRNLNNYEVEYLCDYKVVKGVEYYLVKWKGWPDSTNTWEPLWNLRCPQLLQQFSDDKNTYLSQGRKRKAITSKDNNKSLQPAVAEYIVQKARQRIALQRWQDYLNRRKNHKGMIFVENTVDLEGPPSDFYYINEYRPAPGITLNSEATFGCSCTNCFFEKCCPAEAGVVLAYNKNRQIKIQPGTPIYECNSRCRCGPDCPNRIVQKGTQYSLCIFRTSNGCGWGVKTLVKIKRMSFVMEYVGEVITSEEAERRGQLYDNKGITYLFDLDYESDEFTVDAARYGNVSHFVNHSCDPNLQVFSVFIDNLDTRLPRIALFSTRTIKAGEELTFDYQMKGSGELSSDSIDYSPARKRVRTQCKCGAETCRGYLN", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9EQQ0-1", "uniprot_id": "SUV92_MOUSE", "id": "Q9EQQ0-1", "name": "Histone-lysine N-methyltransferase SUV39H2", "aln": "MATARAKARGSEAGARCHRAPGPPPRPKARRTARRRRAETLTARRSRPSAGERRAGSQRAWSGAPRAAVFGDECARGALF------------------------------KAWCVPCLVSLDTLQELCRKEKLTCKSIGITKRNLNNYEVEYLCDYKVAKGVEYYLVKWKGWPDSTNTWEPLRNLRCPQLLRQFSDDKKTYLAQERKCKAVNSK----SLQPAIAEYIVQKAKQRIALQRWQDYLNRRKNHKGMIFVENTVDLEGPPLDFYYINEYRPAPGISINSEATFGCSCTDCFFDKCCPAEAGVVLAYNKKQQIKIQPGTPIYECNSRCRCGPECPNRIVQKGTQYSLCIFKTSNGCGWGVKTLVKIKRMSFVMEYVGEVITSEEAERRGQFYDNKGITYLFDLDYESDEFTVDAARYGNVSHFVNHSCDPNLQVFSVFIDNLDTRLPRIALFSTRTINAGEELTFDYQMKGSGEASSDSIDHSPAKKRVRTQCKCGAETCRGYLN", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9H5I1-1", "uniprot_id": "SUV92_HUMAN", "id": "Q9H5I1-1", "name": "Histone-lysine N-methyltransferase SUV39H2", "aln": "MAAVGAEARG-----------------------------------------------------------------------------------------------------AWCVPCLVSLDTLQELCRKEKLTCKSIGITKRNLNNYEVEYLCDYKVVKDMEYYLVKWKGWPDSTNTWEPLQNLKCPLLLQQFSNDKHNYLSQVKKGKAITPKDNNKTLKPAIAEYIVKKAKQRIALQRWQDELNRRKNHKGMIFVENTVDLEGPPSDFYYINEYKPAPGISLVNEATFGCSCTDCFFQKCCPAEAGVLLAYNKNQQIKIPPGTPIYECNSRCQCGPDCPNRIVQKGTQYSLCIFRTSNGRGWGVKTLVKIKRMSFVMEYVGEVITSEEAERRGQFYDNKGITYLFDLDYESDEFTVDAARYGNVSHFVNHSCDPNLQVFNVFIDNLDTRLPRIALFSTRTINAGEELTFDYQMKGSGDISSDSIDHSPAKKRVRTVCKCGAVTCRGYLN", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "**:. *:**. ***********************************************.*.:******************** **:** **:***:**:.**:* :* **:..* :*:**:*****:**:********** *********************** ********:*****:: .*********:***:*********:*****::**** ************:***:*****************:**** **********************************:********************************************.*********************:***************: ******:***:***** ***** *******", "identical_positions": 353, "similar_positions": 40, "identity": "69.08%" }, { "cls_id": "homologset.agr.MGI:1890404", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9VP51-1", "uniprot_id": "Q9VP51_DROME", "id": "Q9VP51-1", "name": "AB hydrolase-1 domain-containing protein", "aln": "MDTDDNSSGTITGSDLGQRYRHAGDLTGEAPTRPRANIWCSKKYFAEISITVPWGHISGKWYGPQNVQPILGLHGWQDNAGTFDRLMPLLSPDVAFLAIDLPGHGLSSRLPDGCYYNSVDN-LYVIRLIMKQYKWEKVSLVGHSMSSIICFVFAAVFPDKVDMIIGID--ALKPHQRPYPSVIRTMETRLDEFLREDERNRSK--NEPPSYTYDELIERVYIGTFHSVNKEHCKHLMARNIGKSEKYPDKYFFCRDRRLKFYNYAIGSQELCVEMANRIT-CPYLFIKAAQSSYFEDKK--------YYDEVLDVLLK-KPNFEYLEVNG-SHHVHMNDPEAIIAPVNNFIQRFGPAAAAASRQKAKEA--------------------KESKL", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VP50-1", "uniprot_id": "Q9VP50_DROME", "id": "Q9VP50-1", "name": "AB hydrolase-1 domain-containing protein", "aln": "MKVS-------RGLFLLKQLPNVRNSS-SGPTKP---FKILNKHFDEISIPVPWGHISGKWYGPKHVRPIVGMHGWQDNAGTFDTLAPLLPSHLSFLSIDAPGHGLSSWLPPGTSYHSIDL-VLITRRLMEEYNWDKISILAHSMSSINGFVFSALFPDKVDLFVGLD--VLKPPVRSARGIVDSLTERIESALKLERRLKSG--SEPPAYDWDQLVTRLHEGSNKSVSIDACKYLLQRNCKPSTHEPHKYYFSRDNRLKSSLFYTLHQEVPMEMARRIK-CPHLFIKALQAPYYERKE--------YFDEVLAELQK-NPLFEYHEVEG-THHVHLNEPEKVAPIINSFINRYRPL-------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9W047-1", "uniprot_id": "Q9W047_DROME", "id": "Q9W047-1", "name": "AB hydrolase-1 domain-containing protein", "aln": "------------------------------------MGTLSLSDFEAVKIPVPWGHISGRWYGNRNERPILAIHGWLDNLGTFDRLIPLLPDYLGVLCIDLPGHGRSSHLPPGMYYSVYEY-VFTIPLVMKEYGWSKVSLIGHSLGGVLSFIYASLAPHTVDMIVSLD--ILLPLRND----IDYMDLSIEKQLVNVERQKLGNYIEPPSYTHNQLGKVLAAGSFNSVSPELAKHLLHRQLAKSKLYPERFYFTRDIRVKYYHYIDIDDSLGAEMARRIIKKPYLIIKGSLSPYLSVR----------NNEAISILAKDNPHFEFYEVENGTHHLHLHAAEECAGYIVPFIQHHRPPAMTSWTVAGKE------DRSRKPKRFFTWTNKKRSKL", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9W048-1", "uniprot_id": "Q9W048_DROME", "id": "Q9W048-1", "name": "AB hydrolase-1 domain-containing protein", "aln": "---------------------------------------MSLSDFKEVRIPAPWGHISGRWYGNRTERPILAIHGWLDNLGTFDRLIPLLPDYIGVLCIDLPGHGRSAHIQPGMHYAVNDY-VLIIPRVMKEYGWSKVSLMGHSLGGIISFVYTSLAPDTVDMVISLD--ILLPLSKDPKTVIKYLNHSLDKHLVEEERQVEGNLHEPPSYTLAQLTQVLAKGSDNSVTPEFAQHLLHRQVSKSQLYPDRFFFSRDGRVKYYSHLQMEPEFGEALVKRIRRIPCLIIKGSKSDFVEAR----------TEKAVAILRQNNPHFEFYEVEGGTHHVHLHAAEECARYIVPFIRHHRPPALTSWSLSGKEEHLSAEEKRRQQERFFKRSTHAKSKL", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9W045-1", "uniprot_id": "Q9W045_DROME", "id": "Q9W045-1", "name": "AB hydrolase-1 domain-containing protein", "aln": "--------------------------------------MHKRLQYEEVMIPAPWGHIAGRWYGNRADRPILAIHGWLDNLGTFDRLIPLLPDYIGVLCIDLPGHGRSSRLPPGVPYNVYDY-VFIIPRVMKEFGWSKVSLMGHSLGGVMSFMYAAMAPSTVDMIISLD--VLLPRRIED---PSKLTKDIEGYLLEERRQADGTEHEPPSFTLSKLRETLARNSNNSVPQHLADHMLHRQVAKSNMYPEKVFFSRDGRVKFYHIFDIENGLALEMARRIEKKPYLVIKGSLSPFVGPR----------CNETMSILSHDNPNFEFYEVEGGKHHVHLHAAEECARYIVPFIRNHRPP--------------------------------RSSKL", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "O18391-1", "uniprot_id": "KRAK_DROME", "id": "O18391-1", "name": "Probable serine hydrolase", "aln": "------MGQTRVAATTAAQSPAAELSPETNGQTEEPLQLLGEDSWEEFSIAVPWGTVEAKWWGSKERQPIIALHGWQDNCGSFDRLCPLLPADTSILAIDLPGHGKSSHYPMGMQYFIFWDGICLIRRIVRKYNWKNVTLLGHSLGGALTFMYAASFPTEVEKLINID--IAGPTVRGTQRMAEGTGRALDKFLDYETLPESK----QPCYSYDEMIKLVLDAYDGSVDEPSVRVLMNRGMRHNP-SKNGYLFARDLRLKVSLLGMFTAEQTLAYARQIR-CRVLNIRGIPGMKFETPQ--------VYADVIATLRENAAKVVYVEVPG-THHLHLVTPDRVAPHIIRFLKEA----------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9NQF3-1", "uniprot_id": "SERHL_HUMAN", "id": "Q9NQF3-1", "name": "Serine hydrolase-like protein", "aln": "-----------------------------------MAENAAPGLISELKLAVPWGHIAAKAWGSLQGPPVLCLHGWLDNASSFDRLIPLLPQDFYYVAMDFGGHGLSSHYSPGVPYYLQTF-VSEIRRVVAALKWNRFSILGHSFGGVVGGMFFCTFPEMVDKLILLDTPLFLLESDEMENLLTYKRRAIEHVLQVE-ASQE----PSHVFSLKQLLQRQRT-ALTSSAGSC---------------------------------------------------------------------------------------------VRIPS-GSCRPMS---------------C----------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9H4I8-1", "uniprot_id": "SEHL2_HUMAN", "id": "Q9H4I8-1", "name": "Serine hydrolase-like protein 2", "aln": "-----------------------------------MSENAAPGLISELKLAVPWGHIAAKAWGSLQGPPVLCLHGWLDNASSFDRLIPLLPQDFYYVAMDFGGHGLSSHYSPGVPYYLQTF-VSEIRRVVAALKWNRFSILGHSFGGVVGGMFFCTFPEMVDKLILLDTPLFLLESDEMENLLTYKRRAIEHVLQVE-ASQE----PSHVFSLKQLLQRLLK-SNSHLSEECGELLLQRGT---TKVATGLVLNRDQRLAWAENSIDFISRELCAHSIRKLQAHVLLIKAVHGYFDSRQ-NYSEKESLSFMIDTMKSTLKEQFQFVEVPG-NHCVHMSEPQHVASIISSFLQ-CTHMLPAQL--------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "D4A071-1", "uniprot_id": "D4A071_RAT", "id": "D4A071-1", "name": "", "aln": "-----------------------MLPLAYSSRWSRHSSPSPLGLLSELKLAVPWGHIAVKVWGLQKNPPVLCLHGWLDNANSFDKLIPFLPKDFCYVAMDFGGHGLSTHYSPGLPYYHHNF-VSEVRRVVSAFKWTRLSLLGHSFGGVVGGLFACMFPEMVDKLILLDSTPLLMDLNEVENIMTYRRKNIEQTLKVE-DSQK----PPGIFSPEEMLHELLT-KNSHLNEDCGELLLQRGT---TKVAEGLVLNRDQRLSWPQYSFDFMGKELTMHSLRRLQASVLIIKALDGYYDVRRENDLNKASFLLMLDILRSTLKERFQFVEIPG-NHYIHMNKPQIVADIIRSFLQGPPRTTPSRL--------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9EPB5-1", "uniprot_id": "SERHL_MOUSE", "id": "Q9EPB5-1", "name": "Serine hydrolase-like protein", "aln": "-----------------------------------------MGLHSELKLAVPWGHIALKVWGSQKNPPVLCLHGWLDNANSFDRLIPLLPQDFCYMAMDFGGHGLSSHYNPGLPYYQQNF-VSEVRRVATAFKWNQFTLLGHSFGGCVGGTFACMFPEMVDKLILLDSTPFFLDSNEMENILTYRRRNIEHTLQVE-ASQKK---SLRAVSPEEMLQGFLN-NNSHLDKDCGELILQRGT---TKVDAGLVLNRDRRISWPENSFDFVSKEMFVHSAKSLQASVLMIKALQGYYDVRRANDADKAPMHFMVDTLRSTLKERFQFVEVPG-NHYIHMNKPQVVAGVVGPFLQGLQRMTSARL--------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A2BGU9-1", "uniprot_id": "SERHL_DANRE", "id": "A2BGU9-1", "name": "Serine hydrolase-like protein", "aln": "-------------------------MLPAFMSLRHFTTTTMRRAASEFRMPVPWGELRGQVWGPSHGRPVLCLHGWADNSGTFNTLVPLLPNDWRFVAIDFPGHGLSSHRPDGCFYAFPFY-VADVRRVVEALQWKRFSIIGHSMGGNVAGMFSALYPEMVESVVLLDTYGFLP--TEVTDMFTNMRKGINDQIQYDNMANER---KERVYTYEKAKERLKV-ANPYLSDQSADILLERAV---REVDGGFVFTRDFRIN--LKNIIYINIDQCLHVLSQVKAKVMLLLAKDGLFKTFTLPDG------YADRICKSWTDQKATFVEVEG-DHHVHLNNPEAVSSVITDFLQPQSPDQTESQSGNQTSRL------------------------", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . :..*** : : :* *:: :*** ** .:*: * *:*. :.:* *** *: * * : : * ..:::.**:.. : . * *: .: :* :: : : .: . : ", "identical_positions": 27, "similar_positions": 44, "identity": "6.85%" }, { "cls_id": "homologset.agr.MGI:1890409", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9EPC5-1", "uniprot_id": "RET7_MOUSE", "id": "Q9EPC5-1", "name": "Retinoid-binding protein 7", "aln": "MPADLSGTWNLLSSDNFEGYMLALGIDFATRKIAKLLKPQKVIEQNGDSFTIQTCSSLRNYLVKFKVGEEFEEDNKGLDNRKCTSLVTWENDKLTCVQRGEKKNRGWSHWIEGDQLHLEMFCEGQVCKQTFQRA-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D4ABD9-1", "uniprot_id": "D4ABD9_RAT", "id": "D4ABD9-1", "name": "", "aln": "MPADLSGTWNLLSSDNFEGYMLALGIDFATRKIAKLLKPQKVIEQNGDSFSINTCSSLRNYLLKFKVGEEFVEDNKGLDNRKCMSTVTWENDKLTCVQKGEKKNRGWSHWIEGDQLHLEMFCEGQVCKQTFQRA-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q96R05-1", "uniprot_id": "RET7_HUMAN", "id": "Q96R05-1", "name": "Retinoid-binding protein 7", "aln": "MPADLSGTWTLLSSDNFEGYMLALGIDFATRKIAKLLKPQKVIEQNGDSFTIHTNSSLRNYFVKFKVGEEFDEDNRGLDNRKCKSLVIWDNDRLTCIQKGEKKNRGWTHWIEGDKLHLEMFCEGQVCKQTFQRA-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "E9QGL3-1", "uniprot_id": "E9QGL3_DANRE", "id": "E9QGL3-1", "name": "", "aln": "MPVSFCGTWDMVSNANFEGYMIALGIGLYTRKIALKLKQRKVIEQLGDRYVVKTLSTVKNYTFSFRVNEEFQEFTKGLDDRHCKSAVSWEGNKLVCVQKGEKKNRGWAHWIEDDKLHLELHCEDQVCKQVFKRVI", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "**..:.*** ::*. ******:****.: ***** ** :***** ** : ::* *:::** ..*:*.*** * .:***:*:* * * *:.::*.*:*:********:****.*:****:.**.*****.*:*. ", "identical_positions": 77, "similar_positions": 41, "identity": "57.04%" }, { "cls_id": "homologset.agr.MGI:1890410", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9QXG4-1", "uniprot_id": "ACSA_MOUSE", "id": "Q9QXG4-1", "name": "Acetyl-coenzyme A synthetase, cytoplasmic", "aln": "--------------MGLPEERRKSGSGSRAREETGAEGRVRGWSPPPE--------------------------VRRSAHVPSLQRYRELHRRSVEEPREFWGNIAKEFY-WKTACPG-PFLQYNFDVTKGKIFTEWMKGATTNICYNVLDRNVHEKKLGDKVAFYWEGNEPGETTK-ITYRELLVQVCQFSNVLR-KQGIQKGDRVAIYMPMILELVVAMLACARLGALHSIVFAGFSAESLCERILDSSCCLLITTDAFYRGEKLVNLKELADESLEKCREKGFPVRCCIVVKHLGRAELGMNDSPSQSPPVKRPCPDVQ-------------ICWNEGVDLWWHELMQQAGDECEPEWCDAEDPLFILYTSGSTGKPKGVVHTIGGYMLYVATTFKYVFDFHPEDVFWCTADIGWITGHSYVTYGPLANGATSVLFEGIPTYPDEGRLWSIVDKYKVTKFYTAPTAIRMLMKFGDDPVTKHSRASLQVLGTVGEPINPEAWLWYHRVVGSQRCPIVDTFWQTETGGHMLTPLPG-ATPMKPGSASFPFFGVAPAILN-ESGEELEG-EAEGYLVFKQPWPGIMRTVYGNHTRFETTYFKKFPGYYVTGDGCRRDQDGYYWITGRIDDMLNVSGHLLSTAEVESALVEHEAVAEAAVVGHPHPVKGECLYCFVTLCDGHTFSPTLT------------EELKKQIREKIGPIATPDYIQNAPGLPKTRSGKIMRRVLRKIAQNDHD-LGDTSTVADPSVINHLFSHRCLTTQ-----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8I6GJ11-1", "uniprot_id": "A0A8I6GJ11_RAT", "id": "A0A8I6GJ11-1", "name": "Propionate--CoA ligase", "aln": "MRPQRRPRCSELDVMGLPEERRKSGSGSRAREETGAEGRVRGWSPPPE--------------------------VRRSAHVPSLQRYRELHRRSVEEPREFWGNIAKEFY-WKTPCPG-PFLQYNFDVTKGKIFTEWMKGATTNICYNVLDRNVHEKKLGDKVAFYWEGNEPGETTK-ITYRELLVQVCQFSNVLR-KQGVQKGDRVAIYMPMILELVVAMLACARLGALHSIVFAGFSAESLCERILDSSCCLLITTDAFYRGEKLVNLKELADESLEKCREKGFPVRCCIVVKHLGRAELGMNDSPSQSPPVKRPCPDVQGKLKEKSKCIRPQISWNEGVDLWWHELMQQAGDEFEPEWCDAEDPLFILYTSGSTGKPKGVVHTVGGYMLYVATTFKYVFDFHPEDVFWCTADIGWITGHSYVTYGPLANGATSVLFEGIPTYPDEGRLWSIVDKYKVTKFYTAPTAIRMLMKFGDDPVTKHSRASLQVLGTVGEPINPEAWLWYHRVVGSQRCPIVDTFWQTETGGHMLTPLPG-ATPMKPGSASFPFFGVAPAILN-ESGEELEG-EAEGYLVFKQPWPGIMRTVYGNHTRFETTYFKKFPGYYVTGDGCRRDQDGYYWITGRIDDMLNVSGHLLSTAEVESALVEHEAVAEAAVVGHPHPVKGECLYCFVTLCDGHTFSPTLT------------EELKKQIREKIGPIATPDYIQNAPGLPKTRSGKIMRRVLRKIAQNDHD-LGDTSTVADPSVINHLFSHRCLTTQ-----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9NR19-1", "uniprot_id": "ACSA_HUMAN", "id": "Q9NR19-1", "name": "Acetyl-coenzyme A synthetase, cytoplasmic", "aln": "--------------MGLPEERVRSGSGSRGQEEAGAGGRARSWSPPPE--------------------------VSRSAHVPSLQRYRELHRRSVEEPREFWGDIAKEFY-WKTPCPG-PFLRYNFDVTKGKIFIEWMKGATTNICYNVLDRNVHEKKLGDKVAFYWEGNEPGETTQ-ITYHQLLVQVCQFSNVLR-KQGIQKGDRVAIYMPMIPELVVAMLACARIGALHSIVFAGFSSESLCERILDSSCSLLITTDAFYRGEKLVNLKELADEALQKCQEKGFPVRCCIVVKHLGRAELGMGDSTSQSPPIKRSCPDVQ-------------ISWNQGIDLWWHELMQEAGDECEPEWCDAEDPLFILYTSGSTGKPKGVVHTVGGYMLYVATTFKYVFDFHAEDVFWCTADIGWITGHSYVTYGPLANGATSVLFEGIPTYPDVNRLWSIVDKYKVTKFYTAPTAIRLLMKFGDEPVTKHSRASLQVLGTVGEPINPEAWLWYHRVVGAQRCPIVDTFWQTETGGHMLTPLPG-ATPMKPGSATFPFFGVAPAILN-ESGEELEG-EAEGYLVFKQPWPGIMRTVYGNHERFETTYFKKFPGYYVTGDGCQRDQDGYYWITGRIDDMLNVSGHLLSTAEVESALVEHEAVAEAAVVGHPHPVKGECLYCFVTLCDGHTFSPKLT------------EELKKQIREKIGPIATPDYIQNAPGLPKTRSGKIMRRVLRKIAQNDHD-LGDMSTVADPSVISHLFSHRCLTIQ-----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VP61-1", "uniprot_id": "ACSA_DROME", "id": "Q9VP61-1", "name": "Acetyl-coenzyme A synthetase", "aln": "----------------MPAEKS-------------------IYDPNPA--------------------------ISQNAYISSFEEYQKFYQESLDNPAEFWSRVAKQFH-WETPADQDKFLKYNFNISKGPISIKWMEGASTNLCYNLLDRNVRNG-LGDQIAYYWEGNHPDDYSRGLTYRKLLEEVCRFANVLK-DHGIRKGDRVSIYMPMILELPIAMLACARIGAVHSIVFAGFSPDSLAERMFDCKAKLLITADGAWRGEKPLYLKALCDTALEKVEEMGHSVEKCIVVSHLKRVTPCQPDHVEEE------------------------IPWTDDRDYWWHEEMEDKEPACYPEWMDAEDPLFMLYTSGSTGKPKGVLHTTAGYLLYAATTFKIVFDYKPGDIYWCTGDVGWITGHTYVVYGPLANGATSVIFEGTPFFPGNDRYWSVIDKYKVTQFYTAPTAIRALMKFGEGPVLKHNLSGLKVLGSVGEPINPEAWLWYYKYIGKEQCSIVDTFWQTETGGHVITPLPG-ATPMKPGSASFPFFGVKPTLLD-ECGIEIKG-EGEGYLVFSQPWPGMMRTLYNNHERFEDTYFSKFPGYYCTGDGARRDADGYLWITGRVDDMLNVSGHLMSTAEVESVLTEHPRVAESAVVSRPHPVKGECLYCFITPNENEVFDQKLI------------SDLKKMVRERIGPFAMPDVIQNAPGLPKTRSGKIMRRVLRKIAVNDRN-VGDTSTLADEQIVEQLFANRPVEAK-----", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P52910-1", "uniprot_id": "ACS2_YEAST", "id": "P52910-1", "name": "Acetyl-coenzyme A synthetase 2", "aln": "--------------MTIKEHKVVYEAHNVKALKA--PQHFYNSQPGK-------------------------------GYVTDMQHYQEMYQQSINEPEKFFDKMAKEYLHWDAPYTK-VQSGSLNNG-----DVAWFLNGKLNASYNCVDRHAFAN--PDKPALIYEADDESDNKI-ITFGELLRKVSQIAGVLK-SWGVKKGDTVAIYLPMIPEAVIAMLAVARIGAIHSVVFAGFSAGSLKDRVVDANSKVVITCDEGKRGGKTINTKKIVDEGLNGVD----LVSRILVFQRTGTEG----------------------------------IPMKAGRDYWWHEEAAKQRTYLPPVSCDAEDPLFLLYTSGSTGSPKGVVHTTGGYLLGAALTTRYVFDIHPEDVLFTAGDVGWITGHTYALYGPLTLGTASIIFESTPAYPDYGRYWRIIQRHKATHFYVAPTALRLIKRVGEAEIAKYDTSSLRVLGSVGEPISPDLWEWYHEKVGNKNCVICDTMWQTESGSHLIAPLAG-AVPTKPGSATVPFFGINACIIDPVTGVELEGNDVEGVLAVKSPWPSMARSVWNHHDRYMDTYLKPYPGHYFTGDGAGRDHDGYYWIRGRVDDVVNVSGHRLSTSEIEASISNHENVSEAAVVGIPDELTGQTVVAYVSLKDGYLQNNATEGDAEHITPDNLRRELILQVRGEIGPFASPKTIILVRDLPRTRSGKIMRRVLRKVASNEAEQLGDLTTLANPEVVPAIISAVENQFFSQKKK", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "Q01574-1", "uniprot_id": "ACS1_YEAST", "id": "Q01574-1", "name": "Acetyl-coenzyme A synthetase 1", "aln": "-----------MSPSAVQSSKLEEQSSEIDKLKAKMSQSAATAQQKKEHEYEHLTSVKIVPQRPISDRLQPAIATHYSPHLDGLQDYQRLHKESIEDPAKFFGSKATQFLNWSKPFDK-VFIPDPKTGRPSFQNNAWFLNGQLNACYNCVDRHALKT--PNKKAIIFEGDEPGQGYS-ITYKELLEEVCQVAQVLTYSMGVRKGDTVAVYMPMVPEAIITLLAISRIGAIHSVVFAGFSSNSLRDRINDGDSKVVITTDESNRGGKVIETKRIVDDALRETP----GVRHVLVYRKTNNPS----------------------------------VAFHAPRDLDWATEKKKYKTYYPCTPVDSEDPLFLLYTSGSTGAPKGVQHSTAGYLLGALLTMRYTFDTHQEDVFFTAGDIGWITGHTYVVYGPLLYGCATLVFEGTPAYPNYSRYWDIIDEHKVTQFYVAPTALRLLKRAGDSYIENHSLKSLRCLGSVGEPIAAEVWEWYSEKIGKNEIPIVDTYWQTESGSHLVTPLAGGVTPMKPGSASFPFFGIDAVVLDPNTGEELNTSHAEGVLAVKAAWPSFARTIWKNHDRYLDTYLNPYPGYYFTGDGAAKDKDGYIWILGRVDDVVNVSGHRLSTAEIEAAIIEDPIVAECAVVGFNDDLTGQAVAAFVVLKNKSSWSTATDDELQDIK-----KHLVFTVRKDIGPFAAPKLIILVDDLPKTRSGKIMRRILRKILAGESDQLGDVSTLSNPGIVRHLIDSVKL--------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : . :: .:: *:.:::.*:::* :*:. *.:: *. . *: .. * .** :**:. :: * :*.:. .: :*: :** :*.:.: ** . *::*** *::*:**: * :::** :*:**:**:******. ** :*: * .. ::** * ** * : * : * .*. * :* : : * * . *:*****:******** **** *: .**:* . * : .** : *: : :.*:******:*. **** * ::::**. * :*. .* * :::.:*.*:**.****:* : : *: : ::. .*: **:***** .: * ** . :* :. * ** ****:*.*:::**.* ..* *****:.****: . ::: * *:: . ** *... .**.: *::: :* *: **:. :**:* ****. :* *** ** **:**::***** :**:*:*: : :. *:*.***. . :.*: : .:: : . .* :* ***:* *. * . .**:*********:***: .: : :** :*::: :: :: ", "identical_positions": 217, "similar_positions": 205, "identity": "27.86%" }, { "cls_id": "homologset.agr.MGI:1890430", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0ABK0M0L4-1", "uniprot_id": "A0ABK0M0L4_RAT", "id": "A0ABK0M0L4-1", "name": "PAX-interacting protein 1", "aln": "MSEPAPEVPEELFREVKYYAVGDIDPQVIQLLKAG--KAKEVSYNALASHIISEDGDNPEVGEAREVFDLPVVKPSWVTLSVQCGTLLPVNGFSPESC--QIFFGLTACLSQVSSEDRSALWALVTFHGGSCQLNLNKKCTHLIVPEPKGEKY--ERAVKRTSIKIVTPDWVLDCVSEKRRKDEASYHPRLIIYEE-------------------------------------------EEEEEEEE--GDNEEQDSQNEGSTD-KSSAASSAEASP---------------------------------------------------------------ADQPCSPKARAEVS-----KGELMFDDSSDSSPEKQE----------------------------------------------------------------------------------RSLNWAPAEAPPLST-------------------------------------------------------------------------------------------------------------------------AQHRLPQGKGPGLINLCANVPP--------------VPGDILPPDMRGNLMAAGQN------------------------------------------LQSSERPEMLGTWSPAVRTLRNITNNADIQQISR-----------------------------------------------------PSNVAHILQSLSAPTKNLEQQVAHVQQGHPSASAVLFGQAKGAPET------------------------------------------------HTLQQHHPPQQPQQQHPALHLQP-QIMQLQQ--------------------------------------------QQQ-----QQQQ---QPQPYP------------------------------------------------------------------------------------------------------------------------QPP--SHQFP------QQVHQHQFSQQQLQFPQQ------PLHPQ---------QQLHRPQQQLQPFQQQHALQQQLHQLQQQQLQQHQLAQLQQQQQQQQQQQHNLLQ------------------------------------------QQQQQQ-LQRLHQ------------------------------------------------------------------------------------------QQQMQNQAAHLSQTSQALQHQVL---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------PQQP-LQLPLQPPPQQQQ------------QQQQQQQQQQQQQQ--------------------------------------------------------------------------------------------------------------------------------------LFGHDPAVEIPEESFLLGCVFAIADYPEQMSDKQLLATWKRIIQAHGGTVDPTFTSRCTHLLCESQVSSMYAQALRERKRCVTAHWLNTVLKKKKLMPPHRALHFPVAFPPGG-KPCSQHIISVTGFVDNDRDDLKLMAYLAGAKYTGYLCRSNTVLICKEPSGLKYEKAKEWRIPCVNAQWLGDILLGNFEALRQVQYSRYTAFNLPDPFVPTPHLVLSLLDAWRTPVKVTAELLMSIRLPPKLKPNEVANIQPSKRARGWRDVIKSTDYSCRGPGFSSQHPHDSSQLPVTSVLCRHWAMHMVHRHTCRIEDLPPPTKKLTPELTPYVLFTGF-EPVQVQQYIKKLYILGGEVAESTKKCTHLIASKVTRTVKFLTAISVVKHIVTPDWLEECFKRQMFIDEQNYILRDAEAEVLFSFSLEESLKRAHVSPLFKTKYFYITPGICPSLATMKAIVECAGGKVLAKQPSFRKLMEHKQNKSLSEIILISCENDLHLCREYFARG---IDVHNAEFVLTGVLTQTLDYESYPLQGQ--------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q6NZQ4-1", "uniprot_id": "PAXI1_MOUSE", "id": "Q6NZQ4-1", "name": "PAX-interacting protein 1", "aln": "MSEPAPEVPEELFREVKYYAVGDIDPQVIQLLKAG--KAKEVSYNALASHIISEDGDNPEVGEAREVFDLPVVKPSWVTLSVQCGALLPVNGFSPESC--QIFFGLTACLSQVSSEDRSALWALVTFHGGSCQLNLNKKCTHLIVPEPKGEKY--ERAVKRTSIKIVTPDWVLDCVSEKRRKDEAFYHPRLIIYEE-------------------------------------------EEEEEEE---GDNEEQDSQNEGSTE-KSSVASSAVASP---------------------------------------------------------------AEQPCSPKPRAEVS-----KGELMFDDSSDSSPEKQE----------------------------------------------------------------------------------RSLNWAPAEAPPLNT-------------------------------------------------------------------------------------------------------------------------AQRRLPQGKGPGLINLCANVPP--------------VPGDILPPDMRGNLMAPGQN------------------------------------------LQNSERSEILGTWSPAVRTLRNITNNADIQQINR-----------------------------------------------------PSNVAHILQSLSAPTKSLEQQVARGQQGHPNASAVLFGQAKGAPET------------------------------------------------HVLQQHHPPQQPQQQHPALHLQP-QIMQLQQ--------------------------------------------QQQ-----QQQQQQQQPQPYP------------------------------------------------------------------------------------------------------------------------QPP--SHQFP------QQVHQHQFSQQQLQFPQQ------PLHPQ---------QQLHRPQQQLQPFQQQHALQQQLHQLQQQQLQHHQLAQLQQQQQQQ----HNLLQ------------------------------------------QQQQQQQLQRLQQ------------------------------------------------------------------------------------------QQQMQNQAAHLSQASQALQHQVL---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------PQQP-LQLSLQPPPQQQQ------------QQQ-------------------------------------------------------------------------------------------------------------------------------------------------LFGHDPAVEIPEESFLLGCVFAIADYPEQMSDKQLLATWKRIIQAHGGTVDPTFTSRCTHLLCASQVSSMYTQALRERKRCVTAHWLNTVLKKKKLMPPHRALHFPVAFPPGG-KPCSQHIISVTGFVDNDRDDLKLMAYLAGAKYTGYLCRSNTVLICKEPSGLKYEKAKEWRIPCVNAQWLGDILLGNFEALRQVQYSRYTAFNMPDPFVPTPHLVLGLLDAWRTPVKVTAELLMGVRLPPKLKPNEVANIQPSSKR-------------------------------------------------ARIEDLPPPTKKLTPELTPLVLFTGF-EPVQVQQYIKKLYILGGEVAECTKKCTHLIASKVTRTVKFLTAISVVKHIVTPDWLEECFKRQTFIDEQNYILRDAEAEVLFSFSLEESLKRAHVSPLFKTKYFYITPGICPSLATMKAIVECAGGKVLAKQPSFRKLMEHKQNKSLSEIILISCENDLHLCREYFARG---IDVHNAEFVLTGVLTQTLDYESYKFN----------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6ZW49-6", "uniprot_id": "PAXI1_HUMAN", "id": "Q6ZW49-6", "name": "PAX-interacting protein 1", "aln": "MSDQAPKVPEEMFREVKYYAVGDIDPQVIQLLKAG--KAKEVSYNALASHIISEDGDNPEVGEAREVFDLPVVKPSWVILSVQCGTLLPVNGFSPESC--QIFFGITACLSQVSSEDRSALWALVTFYGGDCQLTLNKKCTHLIVPEPKGEKY--ECALKRASIKIVTPDWVLDCVSEKTKKDEAFYHPRLIIYEE-------------------------------------------EEEEEEEEEEVENEEQDSQNEGSTDEKSSPASSQEGSPS--------------------------------------------------------------GDQQFSPKSNTEKS-----KGELMFDDSSDSSPEKQE----------------------------------------------------------------------------------RNLNWTPAEVPQLAA-------------------------------------------------------------------------------------------------------------------------AKRRLPQGKEPGLINLCANVPP--------------VPGNILPPEVRGNLMAAGQN------------------------------------------LQSSERSEMIATWSPAVRTLRNITNNADIQQMNR-----------------------------------------------------PSNVAHILQTLSAPTKNLEQQVNHSQQGHTNANAVLFSQVKVTPET------------------------------------------------HMLQQQQQAQQQQQQHPVLHLQPQQIMQLQQ--------------------------------------------QQQ-----QQIS----QQPYP------------------------------------------------------------------------------------------------------------------------QQP--PHPFSQQQQQQQQAHPHQFSQQQLQFPQQ------QLHPP---------QQLHRPQQQLQPFQQQHALQQQFHQLQQHQLQQQQLAQLQQQHSLLQQQQQQQIQ------------------------------------------QQQLQRMHQQQQQ------------------------------------------------------------------------------------------QQMQSQTAPHLSQTSQALQHQVP---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------PQQPPQQQQQQQPPPSPQ------------QHQ-------------------------------------------------------------------------------------------------------------------------------------------------LFGHDPAVEIPEEGFLLGCVFAIADYPEQMSDKQLLATWKRIIQAHGGTVDPTFTSRCTHLLCESQVSSAYAQAIRERKRCVTAHWLNTVLKKKKMVPPHRALHFPVAFPPGG-KPCSQHIISVTGFVDSDRDDLKLMAYLAGAKYTGYLCRSNTVLICKEPTGLKYEKAKEWRIPCVNAQWLGDILLGNFEALRQIQYSRYTAFSLQDPFAPTQHLVLNLLDAWRVPLKVSAELLMSIRLPPKLKQNEVANVQPSSKR-------------------------------------------------ARIEDVPPPTKKLTPELTPFVLFTGF-EPVQVQQYIKKLYILGGEVAESAQKCTHLIASKVTRTVKFLTAISVVKHIVTPEWLEECFRCQKFIDEQNYILRDAEAEVLFSFSLEESLKRAHVSPLFKAKYFYITPGICPSLSTMKAIVECAGGKVLSKQPSFRKLMEHKQNSSLSEIILISCENDLHLCREYFARG---IDVHNAEFVLTGVLTQTLDYESYKFN----------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q5XIY8-1", "uniprot_id": "PAXI1_DANRE", "id": "Q5XIY8-1", "name": "PAX-interacting protein 1", "aln": "MSEDDLKVPEELFKDVKFYVVGDIDQKVVQLLKSG--KGKEVSYNALATHIIAEDGDNPEVGESREVFDLPVVKPSWVILSVKCGDLLPVTGFSPESG--QVFFGVTACLPHLA-EDLNALWAFITFYGGDCQLHFNKKCTHLVVPEPKGAKY--ECALRHNNIKIVTPEWILDSVKEKNRKDEMLYHPRLTLYDA-------------------------------------------PEEEGSE----YENERSSRSEGSYSDRRSPHSRR-SSPT--------------------------------------------------------------SSRDASPAGRRSPSTKHERKSELMFDDSDDSSPEKED----------------------------------------------------------------------------------RNLNWTPAEVLPPGP-------------------------------------------------------------------------------------------------------------------------AKRRLQPGKETGLINLCANVPP--------------VPGSFGPPDARMVGAGAGAGGG---------------------------------------VPMGVERLEVMSEWNSAARTLRNITNNTDTQQPSR-----------------------------------------------------PSNVAHIIQSFSASSKGVVDHMGNQGQSGIPNQLLLKAQQQLPPEAQQQLLQQQ------------------------------------QQQSHQLQQQQQQHQMAQQHPMMLPQVMQMHHHQQ--------------------------------------------QQQHQPPPQQQQQQQNQQGFP------------------------------------------------------------------------------------------------------------------------QMPPQSHQFLQQQMHQQMYSQHQQQQQQQQQQQQQHAFPQQMRPQQLPRLPLQHQQQHVLQQQLQ-LQQQHRLQLQLQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQK-----------------------------------------QQQQQQQNQQQMH------------------------------------------------------------------------------------------QQYLQQQQHFLQQQLQQQHMQQL---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------QQQQQMQQQQQQHLQNQQPLQHQNQQVNPHQTQTMLQPPITSAQ--------------------------------------------------------------------------------------------------------------------------------------LFGHEPGHDIPEEGFLVGCIFAIADYPEQMADKQLLATWKRIIQLNGGTVDSALN-RCTHLLCESQVSNTYLQALREGKRCVTAHWLNTVLKKKKMVPPHRTLHLPFSFPPGA-KPCAQHIISVTGFVDSDRDDLKLMAYLAGARYTGYLCRSNTVLICKEPSGLKYEKAKEWRIPCVNAQWLCDILLGNFEALRQIQHSKYTQFNLPDPLAPNHHLVHNLLSAWRIPVKISPEALASLRLQLKQKQADVS-VQPPSKR-------------------------------------------------PKLEELPTPTKSFH------------------------------------------------------------------------------------------------------------------------------------------------------LIQH----------LTSFSQALNLCR----------------------LSST-------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VUB7-1", "uniprot_id": "Q9VUB7_DROME", "id": "Q9VUB7-1", "name": "PAX-interacting protein 1", "aln": "--MENLKISDKLFEDVIYFVLGNLDEEIERFLKSGGAQSKLFLSDQITHMICATNYNEEELSMNLDLYSAIPVTEQWIVHSAKLGRMASTRAFDPSPNQMRLMRGIRVAITNVVAGDRRRLYAMLTYHGAVVTHSFGATNTHLVCGAANGGIYNKALALPKNAIIIVTPDWVTDSLKYKNCMPVETYHPRLLKPIEKQRTQKQQATQQQQIQQQQQLQHQHQMQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQHQQQIIQQQATATSALSDILGFGEDSVAAKSIASIKSQLQASAEQIQQQQLPVPAQQQVVFVRPQPQPQQPAQQSPHQLQQGGPQAPTPAPHPQHQQQLIIQQQKIIPANLQQQPQNQQQIKNILQQRQMKTTQQSQQQQQIQMQLMQQEQQPHPQPLQQQLAQQHPQQIAQQLPQQLSQQHPQQIPQQQQSPRLPTTPTGRQTPRTPSTTPQPVQSPQHHQQIVQQQQVVQQQVGQQQTMVQQQQIVQQQQIVQQQVVQQQQPQQQSVPVSPQIIHQHLMRQQQILNQNQMQLQQIVQSGQALTPQQQQQQRQIQQQLQQVMQQQQQLQMQMQQQQQQQNLQQQQSPRMVQNRSPVMPPSTPSPSLQQQQHHATSNMLPPQSPRQLQSPAPQMTPPPPPSPQNAQQQHLRQQQQMQQNRQQHMMGSPQQPQPQSMMSPQQQQQMQPFQQPVHQQQRMQLQQQQQLAQQQQQQQQQSPQHISPQSPQISQTPPMQAKLHQHQVVPGQATQPQQSFSQQKPIDPTDPVQVAQVLSRSALSSNQDSLIMRQQQLKQQQQMQQQQQMAPQPQQQQMAQQPQQQQQQQPQQQHTPSPRQSPLQQQPTTPTLQQQPNQQNAQQIQQQQQQQQQQQQQQQQQQQQQQVLTQQQPQPGQQQQVITQRHVINTSTAQGQQIIQSHMSLALQKQQQLLHVQQQAQQQPQQQQQITQVQQLPPAQQQQQLPQQHQVQQQQPQQVQFTQQQQIALGAGGQVRIIQQTIQRPPTNVQQQQQVPQQQQQQIIGQFPQQQQLQQQPQQQISGVQQPQQQQQQQKTFIISQQHFNQLSVQQQQQILAQNPQSQNVYVVNQTQQQLVQQQQMLQQQQIIPQQQQQQRMQMQQQ--PQQIVVNQQILSDPQRLQYLQQQQLMQKQQQQQQQQQQQQQQQQQQQQQQLVGQQQQQILIQQQQTPQQQQILQQKLSNDNQQQQIMQLITQQQLPQRTPPPQQQQQQQLLLQQQQQSPQHHPQMQQQHWSPQSPAGGQMASSTPGTPTSVGMQSPLPGGPTTPQPQPQQQFVPRGLRPQTSWPGQPQQQQPQPTQQQQQIVLPPPQQQQPQQQQQHLGQQQQLVMQQPQQQKIVVDEKTHAHLMSLDAHKRAEYITKLNQQNKPRVMLRQQVAYQPRPGAPGSIVATRPAGPVPPGHIIVQHQMPPGLTQQQQVLWLQQQQGKRQVVVRAGTPGLSPIQQQPGAGPQQQQQSPQQQPFNPNDPNQQMLMQRQQLRVQQIPIQQQGPQQLGKQTVQLITGPNGQLIEQQTIVQQPQQQSAPGTPTTPGAGGVLPGNANIMTQTLVMTSTTPDGQPQQSPQQMNLKTKTALANMLSNRLGNNGAQTPQQQIIQLPDGQQPQQQQIVQQVVVTGAIQQQQQQLLLQQQQQQQQQQQMVVQQQLPPQQHVEPPSAAGALRMMGQQHNATAGVPGPPRTQQELLMLQQQQQQQLLQQQQMRRVVALPQQQQAPQQHLVQQQIVVAPTQSPQQQQQMAVGVGVGVPVQRTPHGYIQTRPGQQPIPMPQFYGHNPNLKLPADLFLVGCTFYIVEYDETDGDE--LPIWLDTIRQFGGDIERVYCPRVTHVICRTQRHGVVMQALRDAKRCVTAYWLSDICLKRQLMPPWQPLHLPFPSQFGYRKPLERYIITSEGFEGEEVVRLQQMAEECGAIYTSYLSKVNTVVVCKQLEGNKFNAAKEWNIPMVNALWLSDVCIGNLSGLSQYENPKYQQYNLVAPFRIECNLVAHLLTAWKAPINLTQEAHERVKRHLSDPYGNEQKLKRQKMN------------------------------------------------AFQQEQLPEQIVCVEYPTTTKPPKVIFSQVADAEALKKAVLILGGIVVDSPADATHLVMTRESRTCKLIQACCHVDYVLKSSWIADSAKAGKFVPTDPYRIQHIPVDENLQFNLNTVLCAPTRSTLFAGKYFHVTPDVFPAREEIIRMIESSGGKVEPKRRSGASVAETHMQAP-DSYIIVTCPTDMHLCADLTRHGNPKCHIVSTEFVMSSILRQQLEIEPNLIPYLYNNNNVNSCNSNKS", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ::.:::*.:* ::.:*::* :: ::**:* :.* . : :: * : : :: *:. :::. *. .*: *.: * : .. .*.*.. ::: *: ..:.:: * *:*::*::*. :. . ***: .:* * *: : * ****:*: *.:. * ***** ::: .: ::::..: : . : : : .. . : :* . . . : : :: . :..*:::: *. :*: . ::.* : . ::: : * * ....: **: ... . :: : : :. ..: :.: : : * .: *:: .:: * :* .: . :. * . : * : .*:. : :**:: :* **: * *: ** *** ** . * * * * : : * :* *** ** :: ** *:** :***: :* * :* **:* *::* * ***: : * *** * *: : ** .: .* * * * ** * . * * * ::**:* .:* : **:** * *.:* * .*: *. * *: ** :: . * **::* :* . **:*: ******:**. : *::::** :.**:*.. * ** ::**: ** ..: *: ** .** **.**.: ***::**: * *:: ****.** *** ** *: :**:..* * : .:* :.: *: :** ** **: *:::: * :: . : :: . : *::* . : : : : ::** * . ", "identical_positions": 214, "similar_positions": 285, "identity": "9.11%" }, { "cls_id": "homologset.agr.MGI:1890440", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q91Y78-1", "uniprot_id": "UCHL3_RAT", "id": "Q91Y78-1", "name": "Ubiquitin carboxyl-terminal hydrolase isozyme L3", "aln": "--MEGQRWLPLEANPEVTNQFLKQLGLHPNWQFVDVYGMEP-ELLSMVPRPVCAVLLLFPITEKYEVFRTEEEEKIKSQGQDVTSSVYFMKQTISNACGTIG---LIHAIANNKDKMHFESGSALKKFLEESVAMSPEERARHLENYDAIRV----THETSAHEGQTEAPSIDEKVDLHFIALVHVDGHLYELDGRKP----FPINHGKTSDETLLEDAIEVCKKFMERDPDE---LRFNAIALSAA--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P15374-1", "uniprot_id": "UCHL3_HUMAN", "id": "P15374-1", "name": "Ubiquitin carboxyl-terminal hydrolase isozyme L3", "aln": "--MEGQRWLPLEANPEVTNQFLKQLGLHPNWQFVDVYGMDP-ELLSMVPRPVCAVLLLFPITEKYEVFRTEEEEKIKSQGQDVTSSVYFMKQTISNACGTIG---LIHAIANNKDKMHFESGSTLKKFLEESVSMSPEERARYLENYDAIRV----THETSAHEGQTEAPSIDEKVDLHFIALVHVDGHLYELDGRKP----FPINHGETSDETLLEDAIEVCKKFMERDPDE---LRFNAIALSAA--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P58321-1", "uniprot_id": "UCHL4_MOUSE", "id": "P58321-1", "name": "Ubiquitin carboxyl-terminal hydrolase isozyme L4", "aln": "--MEGQRWLPLEANPEVTNQFLKQLGLHPNWQFVDVYGMES-ELLSIIPRPVCAVLLLFPITEKYEVFRTEEEEKIKSQGQDVTSSVYFMKQTISNACGTIGTIGLIHAIANNKDKVHFESGSTLKKFLEESVSMSPEERAKYLENYDAIRV----THETSAHEGQTEAPSIDEKVDLHFIALVHVDGHLYELDGWKP----FPINHGKTSDETLLEDVIKVCKKFMERDPDE---LRFNAIALSAA--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P35122-1", "uniprot_id": "UCHL_DROME", "id": "P35122-1", "name": "Ubiquitin carboxyl-terminal hydrolase", "aln": "----MLTWTPLESNPEVLTKYIHKLGVSPAWSVTDVIGLED-DTLEWIPRPVKAFILLFPCSETYEKHRAEEHDRIKEVEEQHPEDLFYMRQFTHNACGTVA---LIHSVANNKE-VDIDRG-VLKDFLEKTASLSPEERGRALEKDEKFTA----DHEALAQEGQTNAAN-HEKVIHHFIALVNKEGTLYELDGRKS----FPIKHGPTSEETFVKDAAKVCKEFMARDPNE---VRFTVLALTAAQQ", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P35127-1", "uniprot_id": "UBL1_YEAST", "id": "P35127-1", "name": "Ubiquitin carboxyl-terminal hydrolase YUH1", "aln": "MSGENRAVVPIESNPEVFTNFAHKLGLKNEWAYFDIYSLTEPELLAFLPRPVKAIVLLFPINE--------DRKSSTSQQITSSYDVIWFKQSVKNACGLYA---ILHSLSNNQS--LLEPGSDLDNFLKSQSDTSSSKNRFDDVTTDQFVLNVIKENVQTFSTGQSEAPEATADTNLHYITYVEENGGIFELDGRNLSGPLYLGKSDPTATDLIEQELVRVRVASYMENANEEDVLNFAMLGLGPNWE", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *:*:**** .:: ::**: * *: .: : * :**** *.:**** .* :.. .. . .: :::* **** . ::*:::**:. :: * *..**:. *..:. . : : : **::*.. .. *:*: *. :* ::**** : : : . *: : : :: .* .:.:* :.* :.* . ", "identical_positions": 50, "similar_positions": 80, "identity": "20.08%" }, { "cls_id": "homologset.agr.MGI:1890444", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q6MG77-1", "uniprot_id": "DXO_RAT", "id": "Q6MG77-1", "name": "Decapping and exoribonuclease protein", "aln": "MEPRGTKRKAEKTEVAKTWNKLPRSLPSLRTQPSLYSGPFPFYRRPSELGCFSLDAQRQYHGDARALRYYSPPPINGPGPDFDLRDGYPDRYQPRDEEVRERLDHLLRWVLEHRNQLEGGPG------WLAGATVTWRGHLTKLLTTPYERQE--GWQLAASRFQGTLYLSEVETPAARAQRLARPPLLR-----ELMYMGYK-FEQYMCADKPGGSP-------DPSGEVNTNVAFCSVLRSRLGNHPLLFSGEVDCLNPQAPCTQPPS------CYVELKTSKEMHSPGQWRSFYRHKLLKWWAQSFLPGVPYVVAGFRNPEGFVCSLKTFPTMEMFENVRNDQE--GWNPSVCMNFCAAFLSFAQSTVVQDDPRLVHLFSWEPGGP----VTVSVHRD-APYAFLPSWYVEAMTQDLPSLSKTPSPKD-----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O70348-1", "uniprot_id": "DXO_MOUSE", "id": "O70348-1", "name": "Decapping and exoribonuclease protein", "aln": "MEPRGTKRKAEKTEVEKPLNKLPRAVPSLRTQPSLYSGPFPFYRRPSELGCFSLDAQRQYHGDARALRYYSPPPINGPGPDFDLRDGYPDRYQPRDEEVQERLDHLLRWVLEHRNQLEGGPG------WLAGATVTWRGHLTKLLTTPYERQE--GWQLAASRFQGTLYLSEVETPAARAQRLARPPLLR-----ELMYMGYK-FEQYMCADKPGGSP-------DPSGEVNTNVAYCSVLRSRLGNHPLLFSGEVDCLNPQAPCTQPPS------CYVELKTSKEMHSPGQWRSFYRHKLLKWWAQSFLPGVPHVVAGFRNPEGFVCSLKTFPTMEMFENVRNDRE--GWNPSVCMNFCAAFLSFAQSTVVQDDPRLVHLFSWEPGGP----VTVSVHRD-APYAFLPSWYVETMTQDLPPLSKTPSPKD-----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O77932-1", "uniprot_id": "DXO_HUMAN", "id": "O77932-1", "name": "Decapping and exoribonuclease protein", "aln": "MDPRGTKRGAEKTEVAEPRNKLPRPAPSLPTDPALYSGPFPFYRRPSELGCFSLDAQRQYHGDARALRYYSPPPTNGPGPNFDLRDGYPDRYQPRDEEVQERLDHLLCWLLEHRGRLEGGPG------WLAEAIVTWRGHLTKLLTTPYERQE--GWQLAASRFQGTLYLSEVETPNARAQRLARPPLLR-----ELMYMGYK-FEQYMCADKPGSSP-------DPSGEVNTNVAFCSVLRSRLGSHPLLFSGEVDCTDPQAPSTQPPT------CYVELKTSKEMHSPGQWRSFYRHKLLKWWAQSFLPGVPNVVAGFRNPDGFVSSLKTFPTMKMFEYVRNDRD--GWNPSVCMNFCAAFLSFAQSTVVQDDPRLVHLFSWEPGGP----VTVSVHQD-APYAFLPIWYVEAMTQDLPSPPKTPSPK------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VXA8-1", "uniprot_id": "DXO_DROME", "id": "Q9VXA8-1", "name": "Decapping and exoribonuclease protein Rai1", "aln": "-----MAENAGFISVPWGQHKLG----------AMYNTPFPSISRPKCIGVCSINASREFVDDASCASYLAGQPWP-PLP-FDLNGGIEDVIRKPVENGKRDLEIMLTYIKQHQKELLRQSSSDARNLRLDSDFVTLRGILRQIMCLQYDNR---SFRVKATLLNGNVYMCKEETPEQQLENANMSRAQR-----VMCSWGFK-FEQYLTSAQAQGKP-------VTNVPVNEAEEFMGVYRTNLAGILMLYGAELDCVDSKEPVDFKDCRVLDSLKFVELKTSVFNMNPHQIRTFKSFKSANWWSQSFLVGITTLYVGLRDTKGMLQRIDEIDVATLARNKP-------WSASAMAWYLEQFLRNLKKLLVNINDPFAVVQVTFLNKH----ASYEVLRG-PEHQILPNWYRDLLKTRS----------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9V629-1", "uniprot_id": "CUFF_DROME", "id": "Q9V629-1", "name": "Protein cutoff", "aln": "-------MNSNYTILNIRAHSWAE----------KDNLVFPTITKPVSNGWFAWSPIGQFEPNSQKVPYVVVP----PSIKFPISLRYKDSPPKLEKKPNIFLDNMLQYIESSSYMYVMVRNN--QQAQLNANIVCTSEVLELMMCAPYEKKT--GWSLGVTRYRNTMYICRIDVE--QPDPIDQDNLKR-----AMQEFWLRNLRTHCVFENGIKMH-------QHNQSSEEHLRFHGVFSFDLNGNRVLFDSPVLAEMPSTTLNGSALS------WVDLQIRPMFMSRLDWPEHNRTEALKWWVKCFLLGIESLYIARRDENAHVHNIEKTLVRDLWKSCEKD-----WSPTVCANFMIYLLNCISQVMAPIDCPSTVYLFQFDASQG--TVSYKGLRGRNQYTFVSDWFRMMLDDHTNDMCKTPNLQTMSSIV", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P53063-1", "uniprot_id": "DXO_YEAST", "id": "P53063-1", "name": "Decapping nuclease RAI1", "aln": "-----MGVSANLFVKQR--------------------GSTTALKQPKEIGFYSRTKDEEYLISDDTNLNYYYLPDAELDRKLDLSSGFQKFKDYYKDFEDR---CSLRGLLETIESSERHKGK-----KINADIITFRGIARKLISCAFDSPSFNTVDLRIVSFNGQLFIKEVPEAVNAAKASSATEAGRNINQDLNVFTGYK-FETLATLSNPLQYTPREVIEKRTKRIVSHGDEYISVVRTGVGNCKLILGAEVDCIFDFKENGRDNLK-----HYAELKCTQQVANISDTHKFER-KLFRTWLQCFLVGIPRIIYGFKDDHYVLKTVEEFSTEEVPVLLKNNNPQVGSACLEAIKWYGLLTEWLLKMIPRDEDPHSQIRAFKLVFENNHLRLSEIEESDEEYSGLIDG-EHILSNGFKEWRKSLK--------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . :* * : :: . : : . . * : . . : : :: :: : .. ::: . . * : :. : . . : .* : . :: .. : . :.:*: . : . : . * :.** *: : . :: . : :. . : : : . : : . .. : : : ", "identical_positions": 10, "similar_positions": 77, "identity": "2.29%" }, { "cls_id": "homologset.agr.MGI:1890446", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "F1LX95-1", "uniprot_id": "F1LX95_RAT", "id": "F1LX95-1", "name": "", "aln": "--------------------------------------------------------------------------------------------------MAVSAPP-VISATSTSAGVPGGLFRAEP---------------------LYSSPGEPPRLTPNMIN----------------------SFMASNHNGSVVGGGIGGGSGGTSNTNTNECRMVDMHGVKVASFLMDGQELICLPQVFDLFLKHLVGGLHTVYTKLKRLDISPVVCTVEQVRILRGLGAIQPGVNRCKLITRKDFETLFTDCTNARRKRQM---TRKQAVNSSRPGRPPKRSLG-VLQDNARLLPH--------------------------------------------------AVPGLLSPGLITP---TGITAAAMAEAMKLQKMKLMAMNTLQGNGSQNGTESEPDDLNSTTGGSESSWDKEKIQSPLAAPGAQHGIAHAALAGQ-PGLGGAPTLNPLQQNHLLSNRLDLPFMMMP-------------HPLLPVSLPPASVAMAMNQMNHLN---------TIANMAAAAQIHSPLSRAGASVIKERIPESPSPAPSLEESHRPGSQTSSHPSSSVSSSPSQMDHQSERMVMMPNNREEIIIDQDNGQSIKKFQRDNKDIQLSQHHLLNTFLHWIELAPL--------SKKSLLHQKEVPAQIPMMKSPLDKIQLAPGQALPPGFPGPFIFADSLSSVETLLTNIQVNNISINKINGLLKVALDNARIQEKQIQQEKKELRIELYREREIRENLERQLAVELQSRSTMQKRLKKEKKAKRKLQEALEFESKRRE------------------------------QVEQALKQATSGDSGLRMLKDSGIPDIEIENSGTPHDSAAMQGGNYYCLAMAQQLCSA--------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q925Q8-1", "uniprot_id": "DACH2_MOUSE", "id": "Q925Q8-1", "name": "Dachshund homolog 2", "aln": "--------------------------------------------------------------------------------------------------MAVSAPP-VISATSSSAGVPGGLFRAEP---------------------LYSSPGEPPRLTPNMIN----------------------SFMANNHNGSVLGGGIGGGSGGSSNTNTNECRMVDMHGVKVASFLMDGQELICLPQVFDLFLKHLVGGLHTVYTKLKRLDISPVVCTVEQVRILRGLGAIQPGVNRCKLITRKDFETLFTDCTNARRKRQM---TRKQAVNSSRPGRPPKRSLG-VLQDNARLLPH--------------------------------------------------AVPGLLSPGLITP---TGITAAAMAEAMKLQKMKLMAMNTLQGNGSQNGTESEPDDLNSTTGGSESSWDKDKIQSPLAASGPQHGIAHAALAGQ-PGLGGAPTLNPLQQNHLLSNRLDLPFMMMP-------------HPLLPVSLPPASVAMAMNQMNHLN---------TIANMAAAAQIHSPLSRAGASVIKERIPESPSPAPSLEESHRPGSQTSSHPSSSVSSSPSQMDHHSERMVMMPNNREELIVDQDNGQSIKKFQRDNK--------------------------------------EEVPAQIPVMKSPLDKIQLAPGQALHPGFPGPFIFADSLSSVETLLTNIQG----------LLKVALDNARIQEKQIQQEKKELRIELFREREIRENLERQLAVELQSRSTMQKRLKKEKKAKRKLQEALEFESKRRE------------------------------QVEQALKQATSGDSGLRMLKDSGIPDIEIENSGTPHDSAAMQGGNYYCLAMAQQLCSA--------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q96NX9-1", "uniprot_id": "DACH2_HUMAN", "id": "Q96NX9-1", "name": "Dachshund homolog 2", "aln": "--------------------------------------------------------------------------------------------------MAVSASP-VISATSSGAGVPGGLFRAEP---------------------LYSTPREPPRLTPNMIN----------------------SFVVNNHSNSAGGGGRG-------NTNTNECRMVDMHGMKVASFLMDGQELICLPQVFDLFLKHLVGGLHTVYTKLKRLDISPVVCTVEQVRILRGLGAIQPGVNRCKLITRKDFETLFTDCTNARRKRQM---TRKQAVNSSRPGRPPKRSLG-VLQENARLLTH--------------------------------------------------AVPGLLSPGLITP---TGITAAAMAEAMKLQKMKLMAMNTLQGNGSQNGTESEPDDLNSNTGGSESSWDKDKMQSPFAAPGPQHGIAHAALAGQ-PGIGGAPTLNPLQQNHLLTNRLDLPFMMMP-------------HPLLPVSLPPASVAMAMNQMNHLN---------TIANMAAAAQIHSPLSRAGTSVIKERIPESPSPAPSLEENHRPGSQTSSHTSSSVSSSPSQMDHHLERM------------------------------------------------------------------EEVPVQIPIMKSPLDKIQLTPGQALPAGFPGPFIFADSLSSVETLLTNIQG----------LLKVALDNARIQEKQIQQEKKELRLELYREREIRENLERQLAVELQSRTTMQKRLKKEKKTKRKLQEALEFESKRRE------------------------------QVEQALKQATTSDSGLRMLKDTGIPDIEIENNGTPHDSAAMQGGNYYCLEMAQQLYSA--------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AB32T9A7-1", "uniprot_id": "A0AB32T9A7_DANRE", "id": "A0AB32T9A7-1", "name": "", "aln": "--------------------------------------------------------------------------------------------------MAVSATPPVLSPTSTPGGAS--LFRPDS---------------------LYSSPAESPRLTSSMIN----------------------SFITG--GGSTNGNGPG-------GVHNNECKMVEVHGVKVASFTVDGQELICLPQVFDLFLKHLVGGLHTVYTKLKRLDICPVVCTVEQVRILRGLGAIQPGVNRCKLITRKDFETLYNDCTNA----------------SSRPGRPPKRSLGVAMQDSSRLLPH--------------------------------------------------SVHGLLSPGLLSP---TGLTAAAMAEAMKLQKMKLMAMNNIHGAGSQNGTESENEELNSSAGGSESSWDKEKLQSPPSS-GAQHGLAHAALSAQ-HGLSGS-HLSSLQQSHLLANRLDLPFMMMP-------------HPLLPVSLPPASVAMAMNQMNHLN---------TIANMAAAAQMHSPLSRAGASVIKECVQDSPSPTPSLEEAPRPGSQPSSHPSSSVSSSPNPHTQSPERLVLNPTDGDLP--ERDTGINMKKMLKEK---------------------------------------DEAQITLPMQKPGFEKLPLGT-QTLPPGFPAPFLFADGLSSVETLLTNIQAAQG-------LLKVAVDNARVQEKQVQQERKELKMELYREREMRESLERQLTSELHSRATIQKRLKKEKKAKRKLQEALEFESKRRE------------------------------QVEQALKQATSPESLRMSLNEAVIPEVKSEHNGNQQENSSVQENRPYSKPPIMY------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q8IP19-1", "uniprot_id": "Q8IP19_DROME", "id": "Q8IP19-1", "name": "", "aln": "MDSVTSEQSENNNNKAGAINNNINSGIERAAGNMNTTAMLMHHQQQQQAAAAAAAAAAQQQQQQHNGRDGSNSSRGANEDRPNGRSSHTGRGSSCSPASSPSRHPSAVSPVSSLNHSMMQQMQQQQQQQQQQQQQQQHHQLSPPPHGMPSGNGLPTGLPPRMPHGLPPHSLGLLNSLQMMHHASPLELMAAAHHHVPPRSYNSPPPISTSDPSANECKLVEYRGQKVAAFIISNETMLCLPQAFELFLKHLVGGLHTVYTKLKRLDIVPLVCNVEQVRILRGLGAIQPGVNRCKLLCCKDFDILYRDCTTARCLSIKPPESNSLQFRSSRPGRPPKRGPVGLSLPPTHLSQHPQLKKHRLDNGDYAYENGHISDMKSPLLANGYNPPPINHMAFMQMNAHHPGAAALMSPGMPPHGLHARPESQMLKAAAQNAGMSAANMDALARSGIWENCRAAYEDIVKHLERLREERTDERQQAMGVGGAVVDRVGNVMVAEHKPRDLSSRNCSPTRQSPVLNLSKSGGNTDHGGSNCDAGSERSDCHSVAGSPARGGSRSLDEGSRSGVGGGVASHVGGGIIGVEDDEEEEENLSDENQSEVDERCLAKDDEDLSDTERDNLSTGSAAAAAAAAAAAAHQLHQHAASHHHQTVGLSHLGVVPPHQRGSPSSAEAAAAALQHQRALNYSQLAAAAAVANGAAVGGGAVANGPTGGGGALTPNEALLAANDAAALAGGLALGP-LGIDAHAAVPASSTETLLRNIQS----------LLKVAADNARQQERQISYEKAELKMDVLREREVKDSLERQLVDERKLRVLYQKRFRRERKIRIRYQQQLGGGSGAVKGSPNANGSGGGGSGSACSESEACGGGGGDAKCNNNNNNNNNNNNSNSSSHGGDVETMKENDAGSEKSDKSLASNSSCDVTAGHSAGSVSGSISAGLNCPDSPTHFKREPSSDHEGSVERQPRSSAASLAAHDEDNTKRCGSRDRDERPPSGSAASVAAEGSLAAAAAAAAAAAAAAASNGKGPWSYPGIDLMATGAFWQNYSESLAQELEMERKSRAANAERDVKSPLSERPTAYYKNSVLFGSAN", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : * * .:*..*: :: : : * .. *.. * : .::. . . . ***::*: :* ***:* :..: ::****.*:********************** *:**.**********************: ***: *: ***.* **********. ::* * .. .*:***: . : : : * : *. *: : * :. .: ::: . ... .:: *: . . . :.:. :: : .: .. :*. :* . *.: . .* :: .. . :. * .: : .. ** . * :.* . . * * . .: .:: .:::.:::. : . . : * :* . : * **.**** *** ***** **** **:*:. *: **:::: ****:::.*****. * : * ***:::*:* : : *: * * : : :: :: .. :. : : :: :. *. :.. :: . ", "identical_positions": 155, "similar_positions": 178, "identity": "14.19%" }, { "cls_id": "homologset.agr.MGI:1890457", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9ES07-1", "uniprot_id": "S15A2_MOUSE", "id": "Q9ES07-1", "name": "Solute carrier family 15 member 2", "aln": "---------------------------------------------MNPFQ-------------------------------------KNESKETLFSPVSTEEMLP-----GPPSPPKKSTPKLFGSSYPLSIAFIVVNEFCERFSYYGMKAVLTLYFLY--------FLHWNEDTSTSVYHAFSSLCYFTPILGAAIADSWLGKFKTIIYLSLVYVLGHVFKSLGAIPILGGKMLHTILSLVGLSLIALGTGGIKPCVAAFGGDQFEE----------------EHAEARTRYFSVFYLSINAGSLISTFITPMLRGDVKCFG-EDCYALAFGIPGLLMVLALVVFAMGSKMYRK-PPPEGNIVAQVTKCIWFAICNRFRNRSEDIPKRQHWLDWAAEKYPKHLIMDVKALTRILFLYIPLPMFWALLDQQGSRWTLQANKMDGDLG-FFVLQPDQMQVLNPFLVLVFIPLFDLVIYRLISKCG-VNFSSLRKMAVGMILACLAFAVAALVEIKINGMIHPQPASQ--EIFLQVLNLADGEIEVTVQGNRNNPLLVESISSFQNTTHYSKLRLETKSQDLHFHLKYNNLSVHNEYSVEEKNCYQLVVHENGES--LSSMLVKDTGIKPANGMTAIRFINTLHKDMNISLDANAPLSVGKDYGVSEYRTVQRGKYPAVHCETEDNVFSLNLGQLDFGTTYLFVITNITNRGLQAWKAEDIPANKLSIAWQLPQYVLVTAAEVMFSVTGLEFSYSQAPSSMKSVLQAAWLLTVAVGNIIVLIVAQFSG-LVQWAEFVLFSCLLLVVCLIFSVMGYYYVPLKSEGIHEATEK-----QIPHIQGNMINL--ETKNTRL---------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q63424-1", "uniprot_id": "S15A2_RAT", "id": "Q63424-1", "name": "Solute carrier family 15 member 2", "aln": "---------------------------------------------MNPFQ-------------------------------------KNESKETLFSPVSTEEMLP-----RPPSPPKKSPPKIFGSSYPVSIAFIVVNEFCERFSYYGMKAVLTLYFLY--------FLHWNEDTSTSVYHAFSSLCYFTPILGAAIADSWLGKFKTIIYLSLVYVLGHVFKSLGAIPILGGKMLHTILSLVGLSLIALGTGGIKPCVAAFGGDQFEE----------------EHAEARTRYFSVFYLAINAGSLISTFITPMLRGDVKCFG-QDCYALAFGVPGLLMVLALVVFAMGSKMYRK-PPPEGNIVAQVIKCIWFALCNRFRNRSGDLPKRQHWLDWAAEKYPKHLIADVKALTRVLFLYIPLPMFWALLDQQGSRWTLQANKMNGDLG-FFVLQPDQMQVLNPFLVLIFIPLFDLVIYRLISKCR-INFSSLRKMAVGMILACLAFAVAALVETKINGMIHPQPASQ--EIFLQVLNLADGDVKVTVLGSRNNSLLVESVSSFQNTTHYSKLHLEAKSQDLHFHLKYNSLSVHNDHSVEEKNCYQLLIHQDGES--ISSMLVKDTGIKPANGMAAIRFINTLHKDLNISLDTDAPLSVGKDYGVSAYRTVLRGKYPAVHCETEDKVFSLDLGQLDFGTTYLFVITNITSQGLQAWKAEDIPVNKLSIAWQLPQYVLVTAAEVMFSVTGLEFSYSQAPSSMKSVLQAAWLLTVAVGNIIVLVVAQFSG-LAQWAEFVLFSCLLLVVCLIFSVMAYYYVPLKSEDTREATDK-----QIPAVQGNMINL--ETKNTRL---------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q16348-1", "uniprot_id": "S15A2_HUMAN", "id": "Q16348-1", "name": "Solute carrier family 15 member 2", "aln": "---------------------------------------------MNPFQ-------------------------------------KNESKETLFSPVSIEEVPP-----RPPSPPKKPSPTICGSNYPLSIAFIVVNEFCERFSYYGMKAVLILYFLY--------FLHWNEDTSTSIYHAFSSLCYFTPILGAAIADSWLGKFKTIIYLSLVYVLGHVIKSLGALPILGGQVVHTVLSLIGLSLIALGTGGIKPCVAAFGGDQFEE----------------KHAEERTRYFSVFYLSINAGSLISTFITPMLRGDVQCFG-EDCYALAFGVPGLLMVIALVVFAMGSKIYNK-PPPEGNIVAQVFKCIWFAISNRFKNRSGDIPKRQHWLDWAAEKYPKQLIMDVKALTRVLFLYIPLPMFWALLDQQGSRWTLQAIRMNRNLG-FFVLQPDQMQVLNPLLVLIFIPLFDFVIYRLVSKCG-INFSSLRKMAVGMILACLAFAVAAAVEIKINEMAPAQPGPQ--EVFLQVLNLADDEVKVTVVGNENNSLLIESIKSFQKTPHYSKLHLKTKSQDFHFHLKYHNLSLYTEHSVQEKNWYSLVIREDGNS--ISSMMVKDTESRTTNGMTTVRFVNTLHKDVNISLSTDTSLNVGEDYGVSAYRTVQRGEYPAVHCRTEDKNFSLNLGLLDFGAAYLFVITNNTNQGLQAWKIEDIPANKMSIAWQLPQYALVTAGEVMFSVTGLEFSYSQAPSSMKSVLQAAWLLTIAVGNIIVLVVAQFSG-LVQWAEFILFSCLLLVICLIFSIMGYYYVPVKTEDMRGPADK-----HIPHIQGNMIKL--ETKKTKL---------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "B0S6T2-1", "uniprot_id": "S15A2_DANRE", "id": "B0S6T2-1", "name": "Solute carrier family 15 member 2", "aln": "---------------------------------------------MGKMK-------------------------------------DKD--------VDAEKYEK-----AQRSP------KLCGTNYPVSIAFIVVNEFCERFSYYGMKAVLTLYFMN--------YLHWDKNLSTAIYHAFSGLCYFTPLLGALIADSWLGKFKTIIYLSIVYVIGHVVKSVGAIPDVGDSTVHIALSMVGLGLIALGTGGIKPCVAAFGGDQFDE----------------DNIDERRKFFSIFYMSINAGSVLSTIITPILRGDVQCFG-GDCYALAFGVPAALMVIALVVFISGSGLYKK-SPPEGNVLVRVCKCIGFAISNRWTN-SKKSPKRSHWLDWAEEKYSKRLIQEIKMVCRVLVLYIPLPMFWALFDQQGSRWTLQATRMNMDFGGGFIIKPDQMQMLNALLILVFIPIFDMGIYPLVGLCR-IKLTPLKKMATGMILAALAFCAATAVEVYVIKTVVEPPPAK--ESLVQVYNLMDSDVTVQFPAHN---VFSEPLKPYEEPSGYSSLPLTGESQLQNVVVSHNGMNYQCRLTFTERMAYSLLLHPTAQHNGSVCNLVKDHITKSETGAAYIRFINTHTENINVTVGT-EEVHASANYGISRNISVPRGEYNKAVCVTDTKEYEINLGLLDFGAFYTVILSEAGNN-LAVKKMEDIQANNIHIGWQIPQYVFLTAGEVMFSITGLEFSYSQAPASMKSVLQAGWLMTVAFGNVIVLIVAEGAG-MEQWVEFLLFAALLVAVSIIFSIMAYFYTYVDPDQLDKLFKEDGDGGKVESSKKDELSLGDMPKQTKM---------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "X2JCG8-1", "uniprot_id": "X2JCG8_DROME", "id": "X2JCG8-1", "name": "Oligopeptide transporter 1", "aln": "MELPAEQVPLLEIQPAAEPVAEPEPSPAAEIAPASPDGSGPSAAAAEEVTPSVATVEDTTPIAAPAESQPSGESNGTAEAKKLPEIAKKNGKEPDQNDKEPDQNGKELAETNDFKNVSETEGQQKKLPYPKSVFFIISNEFCERFNYYGMRTVLVLYLSR--------VLGYSDDTATVVFHIFTMFVYFLCVFGAIISDSWLGKFKTILYLSLVYICGSVLLTLGAIGPLN--LPMETFTMLGLALIALGSGGIKPCVSAFGGDQFKVP---------------EQVKQITSFFSLFYFSINAGSLISTTVTPILREDVSCFDDINCYPLAFGVPAVLMIVSVIIFVLGRSLYKM-KPPAGNMVVLVSSTIWTALTTKCKEKKTNP--REHWLDYADKKYDRQLIDDVKVLMRVLFLYLPLPVFWALFDQQGSRWTFQATRMDGDMG-SWDIKPDQLQVLNPLLILIFIPLYDVALYPALKLVG-IRR-PLQKLTMGGILAGIAFIISGVVELSLEKT-YPDLPYS-QNIQLRIFNADNCDYFFTSNIPGAENVTVTSLNAYTNKDIYAPGSLDVEFSLSSASEACTISADKIPKVLTDNTAWSLFLNPLNGS---GYYWEEDFVDKPSQSHPLIRNVANVPQELSIRWEKASTGEVVYD-DLASKTLLTR--VNSAEYVVMVGERNVGTFDVHTGGVYTLLIK-DNNNIYEANLEEVTSPNSVKILWLVPQYVVMTLGEVMFSVTGLEFSYAQAPPSMKSVLQACWLLTVAFGNVIVVVIAEAALFESQASEFFLFAGLMFADMLIFMVMAYYYVPNDPNK-VEEAQPLTAGDAKTEIP---------ALEGGVENK-----------GKDINE-", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P91679-1", "uniprot_id": "PEPT1_DROME", "id": "P91679-1", "name": "Peptide transporter family 1", "aln": "--------------------------------------------MASEIT------------------------NG------------KNG-----------QNGK-----NGQKEESDSQ-IAPPIPYPKSVAFIISNEFCERFNYYGMRTILVLYLTN--------KLGYNEETATVLFHTFTMLVYIFPLIGALIADGWLGKYKTILYLSLVYSLGAMVVSFGAVPLSG--MPTKAVTVVGLLLIAIGTGGIKPCVSAFGGDQFSLP---------------AQSFQLAKFFSLFYFAINAGSLISTTFTPILRADVHCFGDQDCFSLAFGVPAILMIFSVIIFMAGKRLYRC-QPPAGNMIFGVSRCIADAFKGWQKRRHSEP--MESFLDYAKPTVGSRMVQETKCLGRILRLFLPFPVFWALFDQQGSRWTFQATRMDGNVL-GFQIKPDQMQVVNPLLILGFLPLFDYIIYPALARCG-IRR-PLQKLTLGLLLAALGFFLSAGLEMKMEQAAYRATPIEPDMTHLRIYNGMPCRYEISSAVVQTPRVIEP-LNVWEDLSLQMTESKEYTFNAQPVSGECPSIIDKLRLQPGKSVSYFLAQDKLVEF---ADGLQMAATDTGRTSVRALLNTPDGEGPVLLSTESATSQEPPLTLDKGNVPQLHR--ITPGFARVDINGKKVASFEAKEGRLYSILVTGSARDGYQHNVIEVVALSTVSILWQLPQIVVMTAAEVMFSVTGLEFSYSQSPPSMKSVLQACWLLSVAIGNMLVVVIAEFKFTSSQSGEFTLFASLMLVDMMIFLWLARSYQYKDQREDFEDDDDATIDSVMQSKPKATTVDTTARKTNGIEAEPGYGAYRNHAYDNDFSEA", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VH93-1", "uniprot_id": "Q9VH93_DROME", "id": "Q9VH93-1", "name": "Peptide transporter family 1", "aln": "------------------------------MFRATEIGSEETLPALAELSQVG--------------------------------YERDARDVEWVAWRGERAQLKLAHRSSLPNYGFAPPTIRMKYRYPRAVFFVLATKFFEAFAANGIRTVLALYLRD--------DLNFTESFSTVVLHIFNFFGQFCPIIGAILADSYIGNVRTISGFSFIYAFGWLLLTLTSLPAMG--LPMVLLVSIALLFIAVGNGSIRACITSLGALQFKLP---------------EQSVHLAEYFSFYYFVYYFGIFLSKILPPLVRANTQCFDKAECYPAVFGTLGAAFMMAWFIFLVGKWFYKSEKLSDDNILFKFCGCIKTALVEKWRRRKSTK-RSNYWLHNAVVAYDMGFVNDVSRVLRISKLFIPLPFYFALLAQQDSSWTFQATQMNTTLM-GVTIQPDQAKAVGPIFLFMLIPLWQYITVPLLRRYFNWELQPLHSVTVGGIFSAGAFFCAGALQERIKNS---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------PPQTVNIAWQLPQFLLLMMGELLLSIPGLQFAFTQAPTSMKSVVTAAWFLNNAFGNLIVVLVTELGMLSSQMAEYFFYAVVMLVCIILYALLAFDYTLQERKAGMYVRMDSEAEDRDVPSTSRSGSI------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P32901-1", "uniprot_id": "PTR2_YEAST", "id": "P32901-1", "name": "Peptide transporter PTR2", "aln": "------------MLNHPSQGSDDAQDEKQGDFPVIEEEKTQAVTLKDSYVS------------------------------------DDVANSTERYNLSPSPEDE---DFEGPTEEEMQTLRHVGGKIPMRCWLIAIVELSERFSYYGLSAPFQNYMEYGPNDSPKGVLSLNSQGATGLSYFFQFWCYVTPVFGGYVADTFWGKYNTICCGTAIYIAGIFILFITSIPSVGNRDSAIGGFIAAIILIGIATGMIKANLSVLIADQLPKRKPSIKVLKSGERVIVDSNITLQNVFMFFYFMINVGSLSLMATTELEYHKG--------FWAAYLLPFCFFWIAVVTLIFGKKQYIQ-RPIGDKVIAKSFKVCWILTKNKFDFNAAKP----SVHPEKNYPWNDKFVDEIKRALAACKVFIFYPIYWTQYGTMISSFITQASMME-----LHGIPNDFLQAFDSIALIIFIPIFEKFVYPFIRRYT--PLKPITKIFFGFMFGSFAMTWAAVLQSFVYKAGPWYNEPLGHN----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------TPNHVHVCWQIPAYVLISFSEIFASITGLEYAYSKAPASMKSFIMSIFLLTNAFGSAIGCALSPVTVDPKFTWLFTGLAVACFISGCLFWLCFRKYNDTEEEMNAMDYEEEDEFDLNPISAPKANDIEILEPMESLRSTTKY---------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . . * :: :: * * *: : : *: * .. :* : : * . ::*. ::* : *: .** : :* * .. . :: . .: :*.:..* *:. :: : . *: * .:*: * . . : . : .: : .: . : * * .::: :: : . ::: *.::: * : ** *: : * : ...: :: ::*::: : .: .: * ::. .: : :: : . : : * :* .: .*:: *:.**:::::::*.****.: : :::. *.*. : :: : : . :: * . ", "identical_positions": 46, "similar_positions": 142, "identity": "5.25%" }, { "cls_id": "homologset.agr.MGI:1890463", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "E9PU07-1", "uniprot_id": "E9PU07_RAT", "id": "E9PU07-1", "name": "", "aln": "MGLKLLESRLCLLLLLG----LVTCQR-P---TPSQWFAIQHIYNSSYPQCNAAMLRVNSYTGRCKGINTFLHASFANVVGVCGNPHTTCK-DRISTNCHNSSSQVSITFCNLTTP-ARIYTQCRYQTTGSLKFYTVACNPRTPR-DSPMYPVVPVHLDRIF", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q923L7-1", "uniprot_id": "Q923L7_MOUSE", "id": "Q923L7-1", "name": "", "aln": "MGPKLLESQLCLLLMLGLVLMLASCQK-P---TASQWFATQHITYKANLQCNVEMQAINMHRPRCKGLNTFLHTSFINVVGVCSNPSGLCS-DKISQNCHNSSSRVPITVCNLTTP-RRNYTQCRYQTKGSVEYYTVACEPRVAW-DCPIYPVVPVHLDGTF", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P10153-1", "uniprot_id": "RNAS2_HUMAN", "id": "P10153-1", "name": "Non-secretory ribonuclease", "aln": "MVPKLFTSQICLLLLLGLLAVEGSLHVKPPQFTWAQWFETQHINMTS-QQCTNAMQVINNYQRRCKNQNTFLLTTFANVVNVCGNPNMTCPSNKTRKNCHHSGSQVPLIHCNLTTPSPQNISNCRYAQTPANMFYIVACDNRDQRRDPPQYPVVPVHLDRII", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P12724-1", "uniprot_id": "ECP_HUMAN", "id": "P12724-1", "name": "Eosinophil cationic protein", "aln": "MVPKLFTSQICLLLLLGLMGVEGSLHARPPQFTRAQWFAIQHISLNP-PRCTIAMRAINNYRWRCKNQNTFLRTTFANVVNVCGNQSIRCPHNRTLNNCHRSRFRVPLLHCDLINPGAQNISNCTYADRPGRRFYVVACDNRDPR-DSPRYPVVPVHLDTTI", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* **: *::****:** : : * * :*** *** .. :*. * :* : ***. **** ::* ***.**.* * :: ***.* :*.: *:* .* : ::* * . :* ***: * * * ********* :", "identical_positions": 62, "similar_positions": 33, "identity": "38.27%" }, { "cls_id": "homologset.agr.MGI:1890464", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "E9PU07-1", "uniprot_id": "E9PU07_RAT", "id": "E9PU07-1", "name": "", "aln": "MGLKLLESRLCLLLLLG----LVTCQRPTP----SQWFAIQHIYNSSYPQCNAAMLRVNSYTGRCKGINTFLHASFANVVGVCGNPHTTCKDR-ISTNCHNSSSQVSITFCNLTTPAR-IYTQCRYQTTGSLKFYTVACNPRTPR-DSPMYPVVPVHLDRIF", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q923L6-1", "uniprot_id": "Q923L6_MOUSE", "id": "Q923L6-1", "name": "", "aln": "MGPKLLESRICLLLLLGLVLMLASCLGQTT----SQWFAIQHINNNANLQCNVEMQRINRFRRTCKGLNTFLHTSFANAVGVCGNPSGLCSDN-ISQNCHNSSYRVHITVCNITSWRRTPYTQCRYQAKRSLEYYTVACDPRTPQ-DSPMYPVVPVHLDGTF", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P10153-1", "uniprot_id": "RNAS2_HUMAN", "id": "P10153-1", "name": "Non-secretory ribonuclease", "aln": "MVPKLFTSQICLLLLLGLLAVEGSLHVKPPQFTWAQWFETQHINMTS-QQCTNAMQVINNYQRRCKNQNTFLLTTFANVVNVCGNPNMTCPSNKTRKNCHHSGSQVPLIHCNLTTPSPQNISNCRYAQTPANMFYIVACDNRDQRRDPPQYPVVPVHLDRII", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P12724-1", "uniprot_id": "ECP_HUMAN", "id": "P12724-1", "name": "Eosinophil cationic protein", "aln": "MVPKLFTSQICLLLLLGLMGVEGSLHARPPQFTRAQWFAIQHISLNP-PRCTIAMRAINNYRWRCKNQNTFLRTTFANVVNVCGNQSIRCPHNRTLNNCHRSRFRVPLLHCDLINPGAQNISNCTYADRPGRRFYVVACDNRDPR-DSPRYPVVPVHLDTTI", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* **: *::******* : .. :*** *** .. :*. * :* : **. **** ::***.*.**** * . ***.* :* : *:: . ::* * . :* ***: * : *.* ********* :", "identical_positions": 59, "similar_positions": 33, "identity": "36.42%" }, { "cls_id": "homologset.agr.MGI:1890467", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I6AI89-1", "uniprot_id": "A0A8I6AI89_RAT", "id": "A0A8I6AI89-1", "name": "Vacuolar protein sorting-associated protein 35", "aln": "------------MP-----TTQQSPQDEQEKLLDEAIQAVKVQSFQMKRCLDKNKLMDALKHASNMLGELRTSMLSPKSYYELYMAISDELHYLEVYLTDEFAKGRKVADLYELVQYAGNIIPRLYLLITVGVVYVKSFPQSRKDILKDLVEMCRGVQHPLRGLFLRNYLLQCTRNILPDEGEPTDEETTGDISDSMDFVLLNFAEMNKLWVRMQHQGHSRDREKRERERQELRILVGTNLVRLSQLEGVNVERYKQIVLTGILEQVVNCRDALAQEYLMECIIQVFPDEFHLQTLNPFLRACAELHQNVNVKNIIIALIDRLALFAHREDGPG-------IPAEIKLFDIFSQQVATVIQSRQDMPSEDVVSLQVSLINLAMKCYPDRVDYVDKVLETTVEIFNKLNLEHIATS--------SAVSKELTRLLKIPVDTYNNILT---------VLKLKHFHPLFEYFDYESRKSMSCYVLSNVLDYNTEIVSQD---------------------QVDSIMNLVSTLIQDQPDQPVE-------DPDPEDFADEQSLVGRFIHLLRSEDPDQQYLILNTARKHFGAG-----------------------GNQRIRFTLPPLVFAAYQLAFRYKENSQ--------------MDDKWEKKCQKIFSFAHQTISALIKAELAELPLRLFLQGALAAGEIGFENHETVAYEFMSQAFSLYEDELSDSKAQLAAITLIIGTFERMK-CFSEENHEPLRTQCALAASKLLKKPDQGRAVSTCAHLFWSGRNTDKNGEE------LHGGKRVMECLKKALKIANQCMDPSLQVQLFIEILNRYIYFYEKENDAVTIQVLNQLIQKIREDLPNLESSEETEQINKHFHNTLEHLRSRRESPES-EGPIYEGLIL--------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9EQH3-1", "uniprot_id": "VPS35_MOUSE", "id": "Q9EQH3-1", "name": "Vacuolar protein sorting-associated protein 35", "aln": "------------MP-----TTQQSPQDEQEKLLDEAIQAVKVQSFQMKRCLDKNKLMDALKHASNMLGELRTSMLSPKSYYELYMAISDELHYLEVYLTDEFAKGRKVADLYELVQYAGNIIPRLYLLITVGVVYVKSFPQSRKDILKDLVEMCRGVQHPLRGLFLRNYLLQCTRNILPDEGEPTDEETTGDISDSMDFVLLNFAEMNKLWVRMQHQGHSRDREKRERERQELRILVGTNLVRLSQLEGVNVERYKQIVLTGILEQVVNCRDALAQEYLMECIIQVFPDEFHLQTLNPFLRACAELHQNVNVKNIIIALIDRLALFAHREDGPG-------IPAEIKLFDIFSQQVATVIQSRQDMPSEDVVSLQVSLINLAMKCYPDRVDYVDKVLETTVEIFNKLNLEHIATS--------SAVSKELTRLLKIPVDTYNNILT---------VLKLKHFHPLFEYFDYESRKSMSCYVLSNVLDYNTEIVSQD---------------------QVDSIMNLVSTLIQDQPDQPVE-------DPDPEDFADEQSLVGRFIHLLRSDDPDQQYLILNTARKHFGAG-----------------------GNQRIRFTLPPLVFAAYQLAFRYKENSQ--------------MDDKWEKKCQKIFSFAHQTISALIKAELAELPLRLFLQGALAAGEIGFENHETVAYEFMSQAFSLYEDEISDSKAQLAAITLIIGTFERMK-CFSEENHEPLRTQCALAASKLLKKPDQGRAVSTCAHLFWSGRNTDKNGEE------LHGGKRVMECLKKALKIANQCMDPSLQVQLFIEILNRYIYFYEKENDAVTIQVLNQLIQKIREDLPNLESSEETEQINKHFHNTLEHLRSRRESPES-EGPIYEGLIL--------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q96QK1-1", "uniprot_id": "VPS35_HUMAN", "id": "Q96QK1-1", "name": "Vacuolar protein sorting-associated protein 35", "aln": "------------MP-----TTQQSPQDEQEKLLDEAIQAVKVQSFQMKRCLDKNKLMDALKHASNMLGELRTSMLSPKSYYELYMAISDELHYLEVYLTDEFAKGRKVADLYELVQYAGNIIPRLYLLITVGVVYVKSFPQSRKDILKDLVEMCRGVQHPLRGLFLRNYLLQCTRNILPDEGEPTDEETTGDISDSMDFVLLNFAEMNKLWVRMQHQGHSRDREKRERERQELRILVGTNLVRLSQLEGVNVERYKQIVLTGILEQVVNCRDALAQEYLMECIIQVFPDEFHLQTLNPFLRACAELHQNVNVKNIIIALIDRLALFAHREDGPG-------IPADIKLFDIFSQQVATVIQSRQDMPSEDVVSLQVSLINLAMKCYPDRVDYVDKVLETTVEIFNKLNLEHIATS--------SAVSKELTRLLKIPVDTYNNILT---------VLKLKHFHPLFEYFDYESRKSMSCYVLSNVLDYNTEIVSQD---------------------QVDSIMNLVSTLIQDQPDQPVE-------DPDPEDFADEQSLVGRFIHLLRSEDPDQQYLILNTARKHFGAG-----------------------GNQRIRFTLPPLVFAAYQLAFRYKENSK--------------VDDKWEKKCQKIFSFAHQTISALIKAELAELPLRLFLQGALAAGEIGFENHETVAYEFMSQAFSLYEDEISDSKAQLAAITLIIGTFERMK-CFSEENHEPLRTQCALAASKLLKKPDQGRAVSTCAHLFWSGRNTDKNGEE------LHGGKRVMECLKKALKIANQCMDPSLQVQLFIEILNRYIYFYEKENDAVTIQVLNQLIQKIREDLPNLESSEETEQINKHFHNTLEHLRLRRESPES-EGPIYEGLIL--------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9W277-1", "uniprot_id": "Q9W277_DROME", "id": "Q9W277-1", "name": "Vacuolar protein sorting-associated protein 35", "aln": "MYPWSSSSYGGQIPSAANVRTMPNGLDDQEKLLAEAIGLARKQAFQMNHFLDKERMLDSLKCASTMLGELRTSVLSPKSYYELYMAVTNELCHLELYLSEKIDKK---TDLYELVQYSHTIVPRLYLLITVGIVYIKNDPTLKRSILKDLVEMCRGVQHPLRGLFLRNYLLQCTRNILPDVMVE-ENEHEGNVYDAIDFVLTNFAEMNKLWVRMQHQGHSSEKTRREKEREELKILVGTNLVRLSQLESATLEIYQRLILPGILEQVVSCRDAIAQEYLMECIIQVFPDEFHLKTLDPFLKSCAQLETGVNVKNIIISLIERLAAYNQRSGKTSGNAIDAIIPAEVELFEVFSVQVANIVQTRMDMPLEDTISLQVALLSLAQKVYPDRVDYVDKVLGTTAQILQRMNMNNISHL--------LSVNQELSRLLRICIDFYNNALT---------IIQLQNFCPLLEKFDYTSRKSLALYLVMNILDNETLVPTAD---------------------QADSLLTIITPLIKDDDTNKENGAAAGNTTPDAEEFAEEQGVVARFIHLMRSDEPDMQYKMLQTARKHLGNG-----------------------GGQRLKHVLPPLVFAAYQLAFKYKAIAE--------------QDENWDKKCQKIVQYCHSTISALAKADLADLALRLYLQGALVIGEIGYTNHETVAYEFMTQAFSLYEDEISDSKAQLAAITLIMSTFEQMS-CFGEENAEPLRTNCALAASKLLKKPDQCRGVVACAALFWSGK---QNGEE------MRDEKRTLDCLKKGARIASQCLDTGVQVQLYVELLNHYLFYFERGNSLITVAMLNQLIAKVNEELPNLEPSEETKQIESHYKNTLAHIRSRMESNDSSLEVSFAGITLN-------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P34110-1", "uniprot_id": "VPS35_YEAST", "id": "P34110-1", "name": "Vacuolar protein sorting-associated protein 35", "aln": "--------------------------MAYADSPENAIAVIKQRTALMNRCLSQHKLMESLQHTSIMLTELRNPNLSPKKYYELYVIIFDSLTNLSTYLIENHPQNHHLADLYELVQYTGNVVPRLYLMITVGTSYLTFNEAPKKEILKDMIEMCRGVQNPIRGLFLRYYLSQRTKELLPE----------DDPSFNSQFIMNNFIEMNKLWVRLQHQGPLRERETRTRERKELQILVGSQLVRLSQIIDDNFQMYKQDILPTILEQVIQCRDLVSQEYLLDVICQVFADEFHLKTLDTLLQTTLHLNPDVSINKIVLTLVDRLNDYVTRQLEDDPNATSTNAYLDMDVFGTFWDYLTVLNHERPDLSLQQFIPLVESVIVLSLKWYPNNFDNLNKLFELVLQKTKDYGQKNISLESEHLFLVLLSFQNSKLQLTSSTTAPPNSPVTSKKHFIFQLISQCQAYKNILALQSISLQKKVVNEIIDILMDREVEEMADNDSESKLHPPGHSAYLVIEDKLQVQRLLSICEPLIISRSGPPAN-VASSDTNVDEVFFNRHDEEESWILDPIQEKLAHLIHWIMNTTSRKQTMKNKIQFSLEAQLEILLLIKSSFIKGGINVKYTFPAIITNFWKLMRKCRMIQEYLLKKRPDNKTLLSHYSNLLKQMFKFVSRCINDIFNSCNNSCTDLILKLNLQCAILADQLQLN---EISYDFFSQAFTIFEESLSDSKTQLQALIYIAQSLQKTRSLYKEAYYDSLIVRCTLHGSKLLKKQDQCRAVYLCSHLWWATEISNIGEEEGITDNFYRDGKRVLECLQRSLRVADSIMDNEQSCELMVEILNRCLYYFIHGDESETHISIKYINGLIELIKTNLKSLKLEDNSASMITNSISDLHITGENNVKASSNADDGSVITDKESNVAIGSDGTYIQLNTLNGSSTLIRGVVATASGSKLLHQLKYIPIHHFRRTCEYIESQREVDDRFKVIYV", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . :** : :: *:: *.:.:::::*: :* ** ***.. ****.*****: : :.* *. ** :: : :********: .::*****:**** *:. ::.****::*******:*:****** ** * *:::**: .: :*:: ** ********:**** :: * :**:**:****::******: . ..: *:: :*. *****:.*** ::****:: * ***.*****:**:.:*:: .*. .*.:::*:::*::** : *. . ::.:* * :: : : * *:. :: :.* ::: *: * **:..* ::*:: . : : . ::*: :..:. :* *. :* : : : : :: . :*.: :: ::* :. : : *.: ::.: .** . : * * .: . ::. ::.. .. : :::*: :: *. .::..:*.:: ::* : : : .: *: *:.. . . * : . ::* *:* ** *: .:: ::*:*::***:::*:.:****:** *: * :::: : * :.* ..*:* .****** ** *.* *: *:*: . . ** :. **.::**::. ::*.. :* . :* :*:**: :::: : :. * :: : :. .**:. : .: . *:: .:: *. . * : ", "identical_positions": 213, "similar_positions": 290, "identity": "21.65%" }, { "cls_id": "homologset.agr.MGI:1890470", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P57722-1", "uniprot_id": "PCBP3_MOUSE", "id": "P57722-1", "name": "Poly(rC)-binding protein 3", "aln": "MGEGDAIWAPPILPHSTLGTLSHHPELHFGGKMESKVSEGGLNVTLTIRLLMHG--------------------------------------------------------KEVGSIIGKKGETVKKMREESGARINISE--GNCPERIVTITGPTDAIFKAFAMIAYKFEEDIINSMSNSPATSKPPVT---------------------------LRLVVPASQCGSLIGKGGSKIKEIRESTGAQVQVAGDMLPNSTERAVTISGTPDAIIQCVKQICVVML----ESPPKGATIPYRPKPAST-PVIFAGG-----------------------QAYTIQGQYAIPHPD-------------QLTKLHQLAMQQTPFPPLGQTNPAFPGEKLPLHSSEEAQNLMGQSSGLDASPPAST-----------------HELTIPNDLIGCIIGRQGTKINEIRQMSGAQIKIANATE---GSSERQITITGTPANISLAQYLINARLT-----------------------------SEVTGMGAL------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0ABK0LBV7-1", "uniprot_id": "A0ABK0LBV7_RAT", "id": "A0ABK0LBV7-1", "name": "", "aln": "MGEGDAIWAPSILPHSTLSTLSHHPELHFGGKMESKVSEGGLNVTLTIRLLMHGKLVDRAQLHLWSPWSPGHPGIEELNSPTQTLLLDESFSSPMDSVLWLTQVPGSIPNTEVGSIIGKKGETVKKMREESGARINISE--GNCPERIVTITGPTDAIFKAFAMIAYKFEEDIINSMSNSPATSKPPVT---------------------------LRLVVPASQCGSLIGKGGSKIKEIRESTGAQVQVAGDMLPNSTERAVTISGTPDAIIQCVKQICVVML----ESPPKGATIPYRPKPAST-PVIFAGG-----------------------QAYTIQGQYAIPHPD-------------QLTKLHQLAMQQTPFPPLGQTNPAFPGEKLPLHSSEEAQNLMGQSSGLDASPPAST-----------------HELTIPNDLIGCIIGRQGTKINEIRQMSGAQIKIANATE---GSSERQITITGTPANISLAQYLINARLT-----------------------------SEVTGMGAL------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P57721-1", "uniprot_id": "PCBP3_HUMAN", "id": "P57721-1", "name": "Poly(rC)-binding protein 3", "aln": "MGEGDAFWAPSVLPHSTLSTLSHHPQPQFGRRMESKVSEGGLNVTLTIRLLMHG--------------------------------------------------------KEVGSIIGKKGETVKKMREESGARINISE--GNCPERIVTITGPTDAIFKAFAMIAYKFEEDIINSMSNSPATSKPPVT---------------------------LRLVVPASQCGSLIGKGGSKIKEIRESTGAQVQVAGDMLPNSTERAVTISGTPDAIIQCVKQICVVML----ESPPKGATIPYRPKPAST-PVIFAGG-----------------------QAYTIQGQYAIPHPD-------------QLTKLHQLAMQQTPFPPLGQTNPAFPGEKLPLHSSEEAQNLMGQSSGLDASPPAST-----------------HELTIPNDLIGCIIGRQGTKINEIRQMSGAQIKIANATE---GSSERQITITGTPANISLAQYLINARLT-----------------------------SEVTGMGTL------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9Q4K7-1", "uniprot_id": "A0A8M9Q4K7_DANRE", "id": "A0A8M9Q4K7-1", "name": "", "aln": "----------------------MEPS-----KVQ---SEGGLNVTLTIRLLMHG--------------------------------------------------------KEVGSIIGKKGETVKKMREESGARINISE--GNCPERIVTITGPTDAIFKAFAMIAYKFEEDIINSMSNSPATSKPPVT---------------------------LRLVVPASQCGSLIGKGGSKIKEMRESTGAQVQVAGDMLPNSTERAVTISGTPEAIIQCVKQICVVML----ESPPKGATIPYRPKPAST-PVIFSGGQVRADPLAASAANLSLLLQHQPLPAYTIQGQYAIPHPDLY-----CPSNPQQLTKLHQLAMQQTPFTPLGQTTPAFPG--------------------LDASPPAST-----------------HELTIPNDLIGCIIGRQGTKINEIRQMSGAQIKIANAME---GSSERQITITGTPANISLAQYLINARFRDVAA-----------------------MWNDPSSMTTS------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "M9NEH9-1", "uniprot_id": "M9NEH9_DROME", "id": "M9NEH9-1", "name": "", "aln": "----------------------MEDNNTSSSAGGASIKHEDPSVTLTIRLIMQG--------------------------------------------------------KEVGSIIGKKGEIVNRFREESGAKINISD--GSCPERIVTVSGTTNAIFSAFTLITKKFEEWCS-QFNDVGKVGKTQIP---------------------------IRLIVPASQCGSLIGKSGSKIKEIRQTTGCSIQVASEMLPNSTERAVTLSGSAEQITQCIYQICLVML----ESPPRGATIPYRPKPQVTGPVILANG-----------------------QAFTIQGNYAVPTQETCPVFPLALATGGLHAGISGLADPLLKGAHLQGAIPAHHHHLQQMPDVAKNPLASLAALGLAGMNPASTGGINHTANPANRAQQQQHEMTVSNDLIGCIIGKGGTKIAEIRQISGAMIRISNCEEREGGNTDRTITISGNPDSVALAQYLINMSVELQKANLLEQAQSQQNGGAAAAPGAAAAGVAAVTGAAAPTSATNGAITTVTLTSGTGVVGAGAAGAAGVANGANPAANGGGSNGTISATGYASANGGQATNGSVGVNPAAAAALSSPLASALQLLTKPGALSALSNLSALDLLNLTTLGNTNGAGANPGGPPVQTTGVNRAKGHYATSRFRQHQTETGGEAEKPRNKFNPY", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P38151-1", "uniprot_id": "PBP2_YEAST", "id": "P38151-1", "name": "PAB1-binding protein 2", "aln": "-----MSTETTKPSITTTPTTVLVSPNTLKRKKGEDTSEEQLEAEIKRVALKDADSHSDND------------------------------HDSPDNVPSDVHLRMLCLVKHASLIVGHKGATISRIKSETSARINISNNIRGVPERIVYVRGTCDDVAKAYGMIVRALLEEHGNEDNG----EDIEIS---------------------------INLLIPHHLMGCIIGKRGSRLREIEDLSAAKLFASPNQLLLSNDRILTINGVPDAIHIATFYISQTLLNFQMESPQKNVKRSIYYQPTQFNSVLIDHS-----------------------QPNTIFHQRNHQYHPSD-----------KLLSYKPNKNLPISSTLLSMATPQYTTASVANATAFQPNFVIPNVTVLDGPVISPAPGNHLLMN------FVQQEIFIDEKFVGNVIGKDGKHINSVKESTGCSIIIQDPVE---GSSERRLTIRGTFMASQAAIMLISNKIEIDRSN------------------------AERKRRSPL------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P38199-1", "uniprot_id": "HEK2_YEAST", "id": "P38199-1", "name": "Heterogeneous nuclear rnp K-like protein 2", "aln": "--MSQFFEAATPVAIPTNNTNGGSSDAGSAATGGAPVVGTTAQPTINHRLLLSL--------------------------------------------------------KEAAKIIGTKGSTISRIRAANAVKIGISEKVPGCSDRILSCAGNVINVANAIGDIVDVLNKRNPENEDAAEGEAEEHYYFHFLNHILPAPSKDEIRDLQQLEDIGYVRLIVANSHISSIIGKAGATIKSLINKHGVKIVASKDFLPASDERIIEIQGFPGSITNVLIEISEIILS--------DVDVRFSTERSYFPHLKKSSG-----------------------EPTSPSTSSNTRIEL-------------KIPELYVGAIIGRGMNRIKNLKTFTKTNIVVERKDDDDKDENFRKFIITSKFPKNVK----------------LAESMLLKNLNTEIEKRENYKRKLEAAEGDATVVTERSD-----SASFLEEKEEPQENHDNKEEQS------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . :. : .... *:* ** :.::: ...:*.**: . .:**: * : .* *. : : . . . :.*::. ..:*** *: ::.: : . .: .: : * * :* : :.* . * *. :* .. : : . . : . : . : . . : . :. * : . .:. * : : : : : . ", "identical_positions": 26, "similar_positions": 87, "identity": "3.67%" }, { "cls_id": "homologset.agr.MGI:1890471", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P57724-1", "uniprot_id": "PCBP4_MOUSE", "id": "P57724-1", "name": "Poly(rC)-binding protein 4", "aln": "---------------------------------------------MSSSDAGLEE-------GPELSITLTLRMLMHGKEVGSIIGKKGETVKRIREQSSARITISE--GSCPERITTITGSTAAVFHAVSMIAFKLDEDLCAAPANGGSVSRPPVTLRLVIPASQCGSLIGKAGTKIKEIRETTGAQVQVAGDLLPNSTERAVTVSGVPDAIILCVRQICAVIL----ESPPKGATIPYHPSL-SLGTVLLSAN------------------------QGFSVQGQYGA-------------------------------------VTPAEVTKLQQLSGH-----------AVPFASPSVVPGMDPST------QTSSQEFLVPNDLIGCVIGRQGSKISEIRQMSGAHIKIGNQAEGAG---ERHVTITGSPVSIALAQYLITA--------CLETAKSTSGGTPGSAP------------ADLPTPFSP-----------------------------PLTALPTAPPG-LLGTPYAIS------------------------------------LSNFIGLKPVPFLALPP-----------ASPGPPPG-------------LAAYTAKMAAANGSKKAERQKFSPY", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8I5ZYH1-1", "uniprot_id": "A0A8I5ZYH1_RAT", "id": "A0A8I5ZYH1-1", "name": "Poly(rC)-binding protein 4", "aln": "---------------------------------------------MSSSDAGLEE-------EPELSITLTLRMLMHGKEVGSIIGKKGETVKRIREQSSARITISE--GSCPERITTITGSTAAVFHAVSMIAFKLDEDLCAAPANGGSVSRPPVTLRLVIPASQCGSLIGKAGTKIKEIRETTGAQVQVAGDLLPNSTERAVTVSGVPDAIILCVRQICAVIL----ESPPKGATIPYHPSL-SLGTVLLSAN------------------------QGFSVQGQYGA-------------------------------------VTPAEVTKLQQLSGH-----------AVPFASPSVVPGLDPST------QTSSQEFLVPNDLIGCVIGRQGSKISEIRQMSGAHIKIGNQAEGAG---ERHVTITGSPVSIALAQYLITA--------CLETAKSTSGGTPGSAP------------ADLPTPFSP-----------------------------PLTALPTAPPG-LLGTPYAIS------------------------------------LSNFIGLKPVPFLALPP-----------ASPGPPPG-------------LAAYTAKMAAANGSKKAERQKFSPY", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P57723-1", "uniprot_id": "PCBP4_HUMAN", "id": "P57723-1", "name": "Poly(rC)-binding protein 4", "aln": "---------------------------------------------MSGSDGGLEE-------EPELSITLTLRMLMHGKEVGSIIGKKGETVKRIREQSSARITISE--GSCPERITTITGSTAAVFHAVSMIAFKLDEDLCAAPANGGNVSRPPVTLRLVIPASQCGSLIGKAGTKIKEIRETTGAQVQVAGDLLPNSTERAVTVSGVPDAIILCVRQICAVIL----ESPPKGATIPYHPSL-SLGTVLLSAN------------------------QGFSVQGQYGA-------------------------------------VTPAEVTKLQQLSSH-----------AVPFATPSVVPGLDPGT------QTSSQEFLVPNDLIGCVIGRQGSKISEIRQMSGAHIKIGNQAEGAG---ERHVTITGSPVSIALAQYLITA--------CLETAKSTSGGTPSSAP------------ADLPAPFSP-----------------------------PLTALPTAPPG-LLGTPYAIS------------------------------------LSNFIGLKPMPFLALPP-----------ASPGPPPG-------------LAAYTAKMAAANGSKKAERQKFSPY", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8N1TXT5-1", "uniprot_id": "A0A8N1TXT5_DANRE", "id": "A0A8N1TXT5-1", "name": "", "aln": "-------------------------------------------MRLPGPDSHVRMNCEQDFGDGGMNVTLTLRLLMHGKEVGSIIGKKGETVKRIREESSARINISE--GSCPERIITITGATECVFRAFTMITIKLEEDLAALVANGTVTSKPPVTLRLVIPASQCGSLIGKGGSKIKEIREKTGAQVQVAGDLLPNSTERGVTISGSQDAIIQCVKLICTVIL----ESPPKGATIPYRPSP-APGAVLLAGNQVFETSEFASHPLFSVAQGGLDLQQAYTVQNQYG--------------------------------------IPHSELAKLHQLSMQQG-----LGPIAQATATQVLPAGIESSS------QTASQELLIPNDLIGSIIGRQGTKINEIRQVSGAQIKIGSQLDSTS---DRHVTITGSPISINLAQYLITS--------CLETAKSTAQSSSMSTP------------VDLNMSFTQTAPPASSSAA-------------------ALAAMGGLPHAPILGAPYTLP------------------------------------LSSLLGIKSVPFLALSAPAATAAAAAAAAAAAPAHGS------------LASYTAKISSANGIKKPERQKFAPY", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "M9NEH9-1", "uniprot_id": "M9NEH9_DROME", "id": "M9NEH9-1", "name": "", "aln": "----------------------------------------MEDNNTSSSAGGASIK------HEDPSVTLTIRLIMQGKEVGSIIGKKGEIVNRFREESGAKINISD--GSCPERIVTVSGTTNAIFSAFTLITKKFEE-WCSQFNDVGKVGKTQIPIRLIVPASQCGSLIGKSGSKIKEIRQTTGCSIQVASEMLPNSTERAVTLSGSAEQITQCIYQICLVML----ESPPRGATIPYRPKPQVTGPVILANG------------------------QAFTIQGNYAVPTQETCPVFPLALATGGLHAGISGLADPLLKGAHLQGAIPAHHHHLQQMPDVAKNPLASLAALGLAGMNPASTGGINHTANPANRAQQQQHEMTVSNDLIGCIIGKGGTKIAEIRQISGAMIRISNCEEREGGNTDRTITISGNPDSVALAQYLINMSVELQKANLLEQAQSQQNGGAAAAPGAAAAGVAAVTGAAAPTSATNGAITTVTLTSGTGVVGAGAAGAAGVANGANPAANGGGSNGTISATGYASANGGQATNGSVGVNPAAAAALSSPLASALQLLTKPGALSALSNLSALDLLNLTTLGNTNGAG---ANPGGPPVQTTGVNRAKGHYATSRFRQHQTETGGEAEKPRNKFNPY", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P38151-1", "uniprot_id": "PBP2_YEAST", "id": "P38151-1", "name": "PAB1-binding protein 2", "aln": "MSTETTKPSITTTPTTVLVSPNTLKRKKGEDTSEEQLEAEIKRVALKDADSHSDNDHDS---PDNVPSDVHLRMLCLVKHASLIVGHKGATISRIKSETSARINISNNIRGVPERIVYVRGTCDDVAKAYGMIVRALLEEHGNEDNG----EDIEISINLLIPHHLMGCIIGKRGSRLREIEDLSAAKLFASPNQLLLSNDRILTINGVPDAIHIATFYISQTLLNFQMESPQKNVKRSIYYQPTQFNSVLIDHS------------------------QPNTIFHQRNH-------------------------------------QYHPSDKLLSYKPNK-----------NLPISSTLLSMATPQYT---------------TASVANATAFQPNFVIPNVTVLDGPVISPAPG---------NHLLMNFVQQEIFIDEKFVGN--------VIGKDGKHINSVKESTG-----------CSIIIQD----------------------------------PVEGSSERRLTIRGTFMAS--------------------------------------------QAAIMLISN------------------------------------KIEIDRSN----AERKRRSPL", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .. . : :*:: *... *:*:** :.*::.::.*:*.**: . **** : *: : * :*. : * . :.:.*::* *.:*** *::::**.: :...: .: : * *.:* :*:.* : * . *. .:* *** :... . . ..*:: . * :: : . * . . . . : . .: .. : . * :: :.*. * . . : :. .: : : :: : . . :: .. : . :: :. . :. *:: * ", "identical_positions": 47, "similar_positions": 124, "identity": "7.2%" }, { "cls_id": "homologset.agr.MGI:1890472", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0ABK0M566-1", "uniprot_id": "A0ABK0M566_RAT", "id": "A0ABK0M566-1", "name": "Interleukin family protein", "aln": "MGFFPLFCQSQKANLCSLGGQLPSIVAEGMKAQCASRWLLGMVFVLCSVHIYSLRRCLVSVDMRLLEKSFQEIRRTLQTKDTFKNVTILSTLENLRSIKPVDVCCVTNNLLTFYRDRVFKDHQETSLEVVRRISRIANSFLHMQKTLEQC-VHRQCHCSQEATNATRTIHDNYNQLEVSSAALKSLGELNIFLAWIDRNHQETSAT", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8CJ70-1", "uniprot_id": "IL19_MOUSE", "id": "Q8CJ70-1", "name": "Interleukin-19", "aln": "-----------------------------MKTQCASTWLLGMTLILCSVHIYSLRRCLISVDMRLIEKSFHEIKRAMQTKDTFKNVTILS-LENLRSIKPGDVCCMTNNLLTFYRDRVFQDHQERSLEVLRRISSIANSFLCVQKSLERCQVHRQCNCSQEATNATRIIHDNYNQLEVSSAALKSLGELNILLAWIDRNHLETPAA", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9UHD0-1", "uniprot_id": "IL19_HUMAN", "id": "Q9UHD0-1", "name": "Interleukin-19", "aln": "-----------------------------MKLQCVSLWLLGTILILCSVDNHGLRRCLISTDMHHIEESFQEIKRAIQAKDTFPNVTILSTLETLQIIKPLDVCCVTKNLLAFYVDRVFKDHQEPNPKILRKISSIANSFLYMQKTLRQCQEQRQCHCRQEATNATRVIHDNYDQLEVHAAAIKSLGELDVFLAWINKNHEVMFSA", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1NDI2-1", "uniprot_id": "A0A8M1NDI2_DANRE", "id": "A0A8M1NDI2-1", "name": "Interleukin family protein", "aln": "------------------------MESSFIAYSMFICIVLSGLWDAAQGRRLHLGSCKVNIHTHELRHHFQYVRQGMISGDDHKGIRLLR-KDVMSSLQATESCCFLSQLLHFYMDTVFISYTSSHSLHRRTTSVLANSFLSISKDLRVCHANAHCECGENTRLQLKSIQTAYEKLDQAAGTVKAIGELDSLLEWIESFQQQ----", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . :*. .. * * :. . : :.. *: ::: : : * . .: :* : : ::. : **. .:** ** * ** .: . * * :***** :.* *. * : :*.* ::: : *: *::*: :.::*::***: :* **: : ", "identical_positions": 37, "similar_positions": 60, "identity": "17.96%" }, { "cls_id": "homologset.agr.MGI:1890473", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D4A2T8-1", "uniprot_id": "D4A2T8_RAT", "id": "D4A2T8-1", "name": "Interleukin family protein", "aln": "MRGFRLAFGLFSVVGFLLWTPLTGLKTLHLGSCVITANLQAIQKEFSEIRHSVQAEDENIDVRILRTTESLKDTKLSDRCCFLRHLVRFYLDRVFKVYQTPDHHTLRKISSLANSFLIIKKDLSVCHSHMACHCGEEAMEKYNQILSHFTELELQAAVVKALGELGILLRWMEEML--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9JKV9-1", "uniprot_id": "IL20_MOUSE", "id": "Q9JKV9-1", "name": "Interleukin-20", "aln": "MKGFGLAFGLFSAVGFLLWTPLTGLKTLHLGSCVITANLQAIQKEFSEIRDSVQAEDTNIDIRILRTTESLKDIKSLDRCCFLRHLVRFYLDRVFKVYQTPDHHTLRKISSLANSFLIIKKDLSVCHSHMACHCGEEAMEKYNQILSHFIELELQAAVVKALGELGILLRWMEEML--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9NYY1-1", "uniprot_id": "IL20_HUMAN", "id": "Q9NYY1-1", "name": "Interleukin-20", "aln": "MKASSLAFSLLSAAFYLLWTPSTGLKTLNLGSCVIATNLQEIRNGFSEIRGSVQAKDGNIDIRILRRTESLQDTKPANRCCLLRHLLRLYLDRVFKNYQTPDHYTLRKISSLANSFLTIKKDLRLCHAHMTCHCGEEAMKKYSQILSHFEKLEPQAAVVKALGELDILLQWMEETE--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1NDI2-1", "uniprot_id": "A0A8M1NDI2_DANRE", "id": "A0A8M1NDI2-1", "name": "Interleukin family protein", "aln": "MESSFIAYSMFICIVLSGLWDAAQGRRLHLGSCKVNIHTHELRHHFQYVRQGMISGDDHKGIRLLR-KDVMSSLQATESCCFLSQLLHFYMDTVFISYTSSHSLHRRTTSVLANSFLSISKDLRVCHANAHCECGENTRLQLKSIQTAYEKLDQAAGTVKAIGELDSLLEWIESFQQQ", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*.. :*:.:: : : *:**** : : : ::: *. :* .: : * : .:*:** .: :.. : : **:* :*:::*:* ** * :.. *. * ****** *.*** :**:: *.***:: : ..* : : :*: *..***:***. **.*:*. ", "identical_positions": 53, "similar_positions": 63, "identity": "29.78%" }, { "cls_id": "homologset.agr.MGI:1890474", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9ES17-1", "uniprot_id": "IL21_MOUSE", "id": "Q9ES17-1", "name": "Interleukin-21", "aln": "-------MERTLVCLVVIFLGTVAHKSSPQGPDRLLIRLRHLIDIVEQLKIYENDLDPELLSAPQDVKGHCEHAAFACFQKAKLKPSNPGNNKTFIIDLVAQLRRRLPARRGGKKQKHIAKCPSCDSYEKRTPKEFLERLKWLLQKMIHQHLS---------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A3QPB9-1", "uniprot_id": "IL21_RAT", "id": "A3QPB9-1", "name": "Interleukin-21", "aln": "-------MERTLVCLILIFLGTVAHKSSPQRPDHLLIRLRHLMDIVEQLKIYENDLDPELLTAPQDVKGQCEHEAFACFQKAKLKPSNTGNNKTFINDLLAQLRRRLPAKRTGNKQRHMAKCPSCDLYEKKTPKEFLERLKWLLQKMIHQHLS---------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9HBE4-1", "uniprot_id": "IL21_HUMAN", "id": "Q9HBE4-1", "name": "Interleukin-21", "aln": "MRSSPGNMERIVICLMVIFLGTLVHKSSSQGQDRHMIRMRQLIDIVDQLKNYVNDLVPEFLPAPEDVETNCEWSAFSCFQKAQLKSANTGNNERIINVSIKKLKRKPPSTNAGRRQKHRLTCPSCDSYEKKPPKEFLERFKSLLQKMIHQHLSSRTHGSEDS", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *** ::**::*****:.****.* *: :**:*:*:***:*** * *** **:*.**:**: :** **:*****:**.:*.***: :* : :*:*: *: . *.:*:* .***** ***:.*******:* *********** ", "identical_positions": 86, "similar_positions": 38, "identity": "53.09%" }, { "cls_id": "homologset.agr.MGI:1890475", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I6ASZ0-1", "uniprot_id": "A0A8I6ASZ0_RAT", "id": "A0A8I6ASZ0-1", "name": "", "aln": "----------MPRGLAAP----LLLLILHGGWSCLDLTCYTDYLWTITCVLETWSPNPSILSLTCHDWLLCSQRQDEYEELQDKETSCSLHASGHNTTHMWYTCHMRLSQFMSDDVFTVNMMDQSSNSSQECG----SFVLAESIKPAPPLNVTVT-FSGRYDISWDSIYEEPSNYVLRGKLQYELQYRNLRDPYAVSVLFLMSWQRPVTKLISVDSRNISLLPQEFQKDSSYQLQVRAAPQPGTSFRGTWSEWSDPIIFQTQAEEPEAGWDPHVLLLLAVLILVL-VFMGLKNHLPWRLCKKIWAPVPTPESFFQPLYREHSGNFKKWVNTPFTASSVELGPQS-PTTSVLHLS-----LYPAKGKKFLGPLGLEEQLECDGMSGPGHKC-------QGVSAYSEERDRPYGLVSIDTVTVGDAEGLG-AWPFSCEDDGYPALNLDAVRESGPNGEDLLLVTDPAFLSCGCVSGSGLRLGGSPGSLLDRLRLSFAKEGDWTAGPPWRTGSLEGGSESEAGSP-PGLDMDTFDSGFAGSDCGSPVET-------------DEGPPRSYLRQWVVRTPPPVDSGAQNS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9JHX3-1", "uniprot_id": "IL21R_MOUSE", "id": "Q9JHX3-1", "name": "Interleukin-21 receptor", "aln": "----------MPRGPVAA----LLLLILHGAWSCLDLTCYTDYLWTITCVLETRSPNPSILSLT---------WQDEYEELQDQETFCSLHRSGHNTTHIWYTCHMRLSQFLSDEVFIVNVTDQSGNNSQECG----SFVLAESIKPAPPLNVTVA-FSGRYDISWDSAYDEPSNYVLRGKLQYELQYRNLRDPYAV---------RPVTKLISVDSRNVSLLPEEFHKDSSYQLQVRAAPQPGTSFRGTWSEWSDPVIFQTQAGEPEAGWDPHMLLLLAVLIIVL-VFMGLKIHLPWRLWKKIWAPVPTPESFFQPLYREHSGNFKKWVNTPFTASSIELVPQSSTTTSALHLS-----LYPAKEKKFPGLPGLEEQLECDGMSEPGHWCIIPLAAGQAVSAYSEERDRPYGLVSIDTVTVGDAEGLC-VWPCSCEDDGYPAMNLDAGRESGPNSEDLLLVTDPAFLSCGCVSGSGLRLGGSPGSLLDRLRLSFAKEGDWTADPTWRTGSPGGGSESEAGSP-PGLDMDTFDSGFAGSDCGSPVET-------------DEGPPRSYLRQWVVRTPPPVDSGAQSS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9HBE5-1", "uniprot_id": "IL21R_HUMAN", "id": "Q9HBE5-1", "name": "Interleukin-21 receptor", "aln": "----------MPRGWAAP----LLLLLLQGGWGCPDLVCYTDYLQTVICILEMWNLHPSTLTLT---------WQDQYEELKDEATSCSLHRSAHNATHATYTCHMDVFHFMADDIFSVNITDQSGNYSQECG----SFLLAESIKPAPPFNVTVT-FSGQYNISWRSDYEDPAFYMLKGKLQYELQYRNRGDPWAVS---------PRRKLISVDSRSVSLLPLEFRKDSSYELQVRAGPMPGSSYQGTWSEWSDPVIFQTQSEELKEGWNPHLLLLLLLVIVFIPAFWSLKTHPLWRLWKKIWA-VPSPERFFMPLYKGCSGDFKKWVGAPFTGSSLELGPWSPEVPSTLEVYSCHPPRSPAKRLQLTELQEPAELVESDGVPKPSFWP---TAQNSGGSAYSEERDRPYGLVSIDTVTVLDAEGPC-TWPCSCEDDGYPALDLDAGLEPSPGLEDPLLDAGTTVLSCGCVSAGSPGLGGPLGSLLDRLKPPLADGEDWAGGLPWGGRSPGGVSESEAGSPLAGLDMDTFDSGFVGSDCSSPVECD-------FTSPGDEGPPRSYLRQWVVIPPPLSSPGPQAS", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "X1WC58-1", "uniprot_id": "X1WC58_DANRE", "id": "X1WC58-1", "name": "", "aln": "MHLSRADHSFFPSSSMMASWRATFLLVVCGLLQCYDAACSVNCTTDFISALNCSASDLTGTASCD-------VVASCRDEFSTVNGSCSIRSPQSWCTMEPYELES-IMSFDTNCFITVTQMDKEGDMEIPTQRYSKNIVLYKSTKPKQPFNLTIRNIDGGFNLTWDVAYTDN---VLYEKLIYRVRVLSKSSPEKEN-----------IYTLQQNQQSMVILSEKLQPGLQHVADVQVAVNP-EWFPSMWSEWSDSVEWGVESPQSPE---QYYFVLLAIPIAIILALLLVFSGKLGGIKKLTFQHIPSPQEYFTPLYHTYQGDFKKWVGPVLTFNNFDVLEKSTLLQVLCEKQ------QNQSPEEPANNQSGERDFGQEGQSASKLYFLE-----------NSSQEHSGGHISIDTVTVSDQEGIMGDWSGNSRRQSLDGFVNAN--QRAPEIDQPLQRAAS-----GSLQGSDFDWHLQEHDLENMEQVSLD--------------SYSSNEQSDDGYPQMGLDLDTIDSGFLESECSSPSAFDGNEQIETASLDGVEGSHSNYVKQWVAFTAVQVEAHSSGN", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :* . . :**:: * * * .* .: . . *: . : : . :*:. **:: . * * . : * :: .: *. *:..: . .::* :* ** *:*:*: :.* ::::* * : :* ** *.:: . .* :. :.:.: :*. ::: . .: :*:.. * : . ******.: : .:: : : ::** : * .: .: : : * : :*:*: :* ***: .*:*****.. :* ...:: * . . : . . :* . . ...:::. * :******* * ** *. ... :. .: : .* :: * : . *.:.... .* : : .: * . .:*: * * ***:**:**** *:*.** **. .*::***. .. .. .. .", "identical_positions": 98, "similar_positions": 169, "identity": "16.7%" }, { "cls_id": "homologset.agr.MGI:1890476", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9QXK2-1", "uniprot_id": "RAD18_MOUSE", "id": "Q9QXK2-1", "name": "E3 ubiquitin-protein ligase RAD18", "aln": "--MEVLAEPRWPPG-LAVMKTIDDLLRCGICFEYFNIAVIIPQCSHNYCSLCIRKFLSYKTQCPTCCVAVTEPDLRNNRLLDELVKSMNFARTHLLQFA-LESPPISPVSSTSKKVVVKVHNADAAQHPVKQANRLMDKFLIRETGDCVFELLGKENERKFSPQKELSTSAEIKETSLLGKPVLGLSDANGPVT--PSTS-TMKLDTKVSCPVCGVSIPENHINKHLDSCLSREEKKES---LRS---------------------SAHKRKPLPKTVYNLLSDRDLKKKLKQYGLSVQGNKQQLIKRHQEFVHMYN-AQCDALHPKSAAEIVQEIESMEKTRMRLEASKLNE----NVMVFTKNQTEKEIEEVHSEYRKKHQNAFQLLVDQAKKGYKKTGRVSQAAAMRTDEPAETLPSMRTDEPAETLPSMRTDEPAETLPLMRADEPAETLPSECIAQEDNVSFSDTVSVTNHFPQPQLDSPGPSEPERPDDSSSCTDI---LFSSDSDSCNRND----------------------QNREVSPQQTRRTRASECVEIEPRNKRNKN", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9NS91-1", "uniprot_id": "RAD18_HUMAN", "id": "Q9NS91-1", "name": "E3 ubiquitin-protein ligase RAD18", "aln": "--MDSLAESRWPPG-LAVMKTIDDLLRCGICFEYFNIAMIIPQCSHNYCSLCIRKFLSYKTQCPTCCVTVTEPDLKNNRILDELVKSLNFARNHLLQFA-LESPAKSPASSSSKNLAVKVYTPVASRQSLKQGSRLMDNFLIREMSGSTSELLIKENKSKFSPQKEASPAAKTKETRSVEEIAPDPSEAKRPEP--PSTS-TLKQVTKVDCPVCGVNIPESHINKHLDSCLSREEKKES---LRS---------------------SVHKRKPLPKTVYNLLSDRDLKKKLKEHGLSIQGNKQQLIKRHQEFVHMYN-AQCDALHPKSAAEIVREIENIEKTRMRLEASKLNE----SVMVFTKDQTEKEIDEIHSKYRKKHKSEFQLLVDQARKGYKKIAGMSQKTVTITKE----------------------------------DESTEKLSSVCMGQEDNMT-----SVTNHFSQSKLDSPEELEPDREEDSSSCIDIQEVLSSSESDSCNSSSSDIIRDLLEEEEAWEASHKNDLQDTEISPRQNRRTRAAESAEIEPRNKRNRN", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AB32TQL4-1", "uniprot_id": "A0AB32TQL4_DANRE", "id": "A0AB32TQL4-1", "name": "RING-type E3 ubiquitin transferase", "aln": "--MAQLNEVDLPPN-LSCLKPMDTLLRCPICFEFLNISMMT-QCSHNFCSLCIRKFLSYKLLCPVCNSPSTEQDLRNNRLLDDLVQSFQTARLKLCHSN-LESPPISPETPT-----MVIKGKAARQKGLKKESSNLSHFFQKKTSVTLPSETLHAS-VKSEPMEVCVQQPGIFKQESLEDARNRVKEEKMDVTAFPSTSQSCKPAVKVECPVCGVGVPEQHINKHLDMCLNRDDKKEG---LRS---------------------SGR-RKAMPKLLYTLITVPKLKKMLKECHLSAQGNREQLTRRHQEFTHIYN-AQCDALNPKSAEEIAKEVEANERLKNQLDSKRK------PVIITTKNQTAEEIEEVHSMYRKQHSSEFSRLIAQVKG------RLETKKAQVKQE---------------------------------EGNSTEETDSKG--------------VNYSIQNSSLPISTSLKVKSED---TVIELP--------------------------------------PRSSSPAISEVSVSSSISDIFC-------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P10862-1", "uniprot_id": "RAD18_YEAST", "id": "P10862-1", "name": "Postreplication repair E3 ubiquitin-protein ligase RAD18", "aln": "MDHQITTASDFTTTSIPSLYQLDTLLRCHICKDFLKVPVLT-PCGHTFCSLCIRTHLNNQPNCPLCLFEFRESLLRSEFLVSEIIQSYTSLRSSLLDALRIPKPTPVPENEEVPGPENSSWIELISESESDSVNAADDDLQIVATSERKLAKRSMTDILPLSSKPSKRNFAMFRSERIKKKSKPNEQMAQCPICQQFYPLKALEKTHLDECLTLQSLGKKPKISTTFPTESNPHNKSSSRFKVRTPEVDKSSCGETSHVDKYLNSMMSAEHQRLPKINFTSMTQSQIKQKLSSLGLSTNGTRQNMIKRYNHYEMLWNSNFCDSLEPVDEAELKRQLLSWDVSHNKTPQNSSNKGGISKLMIMKSNGKSSSYRKLLENFKNDKFNRKGWMVMFRKDFARLIREAKMKIKTGSSDS--------------------------------SGSVGHSNDGDGVEKVQ----------SDQGTEDQQMEKDQDTVINEDRVAGERNLP-------------------------------------NEDSTDADLSRELMDLNEYSKDPPGNN---", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .. :. : :* **** ** :::::.:: *.*.:******..*. : ** * * *:.: ::.::::* * * . : .*. * . . .. . ..: . . .. . . . . : . : : .* . : :*.. : . .:*... :*: :: :** :. :: .:*: *.. ** :*.:::: :*::.: ::* **:*.* . *: ::: : : : . ::: ..: . .. :: . :::.: . :: : . ..: .. . . . : . : :: . .. .. . . ", "identical_positions": 44, "similar_positions": 148, "identity": "7.72%" }, { "cls_id": "homologset.agr.MGI:1890478", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q91ZP4-1", "uniprot_id": "S5A4B_MOUSE", "id": "Q91ZP4-1", "name": "Solute carrier family 5 member 4B", "aln": "MASTLSPSITPQTEEPPVVPVRIQNAADISVIVIYF-IVVLAVGLWSMVRSNRGTVGGFFLAGHDMAWWPMGASLFASNIGSNHFVGLAGTGAASGIAIAAVEWNALLMVLVLGWVFLPIYIK---AGVLTMPEYLRKRFGGKRLQIYLSVLSLFIMVALQTSSIIFSGAIFIQLALGLNLYLAVFILLAITAFYTVAGGLASVIYTDSVQTFIMLLGSLILMGFAFAEVGGYESFTEKYMNAIPSVVEGDNLTISPKCYTPQPDSFHVFRDPVTGDIPWPGLIFGMTILAIWYWCADQVIVQRCLCGKNMSHVKAACILCGYLKLLPMFLMVMPGMISRILYTDKVACVVPSECEKQCGTAVGCTNYAYPTLVLELMPDGLRGLMLSVMLASLMSSLTSIFNSASTLFTIDLYTK-IRKKASERELMIAGRIFGMVLIAVSILWVPLVQVSQNGQLFHYIGSVSSYLGPPLGAVFMLAIFFKRVNEQGAFWG--LMVGLVVGLIRLIAEFVYGTGSCVAPSNCPKIICGVHYMYFAIILFFVSIIVILG-VSFLTEPIPDVHLYRLCWSLWNNTEERIDLDAEELETQEEAGGALEED-SEQSRGCLKRACCLLCGLQNTGPKLTKEEEAALRQKFSDTSEKPLWR---------------------------------------TVMNINAVLLLGVAVFVHAYFA-----------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "F1LQV2-1", "uniprot_id": "F1LQV2_RAT", "id": "F1LQV2-1", "name": "", "aln": "MASTLSPSTAPRTEEPPEVSERIQNAADISVIVIYF-LVVLAVGLWSMVRSNRGTIGGFFLAGRDVSWWPMGASLFASNIGSNHFVGLAGTGAASGIAIAAVEWNALLMVLVLGWVFVPIYIK---AGVTTMPEYLRKRFGGKRLQIYLSVLSLFIMVAIQTSSTIFSGAIFIQLALGLNLYLAVFILLAITAFYTVAGGLASVIYTDSVQTFIMLVGSLILMGFAFAEVGGYESFTEKYMNAIPSVVEGDNLTISPKCYTPQPDSFHIFRDPINGDIPWPGLIFGMTILAIWYWCADQVMVQRCLCGKNMSHVKAACIMCGYLKLLPMFLMVMPGMISRILYTDKVACVVPSECVKQCGTAVGCTNYAYPTLVLELMPDGLRGLMLSVMLASLMSSLTSIFNSASTLFTMDLYTK-IRKKASERELMVAGRVFGIVLIVISILWVPLIQASQNGQLFHYISSFSSYIGPPVGAVFLLAIFCKRVNEQGAFWG--LMVGLVIGLIRMITEFIYGTGSCLEPSNCPRIICGVHYMYFAIILFFVSILVILG-VSFLTEPIPDVHLYRLCWSLWNNTEERIDLDAEQ-ETREEVGGALEEDDAEQSRGCLRRACSLFCGLQSTGPKLTEEEEAALRQKFSDTSEKPLWR---------------------------------------NVVNINAILLLAVAVFVHAYFA-----------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9NY91-1", "uniprot_id": "SC5A4_HUMAN", "id": "Q9NY91-1", "name": "Probable glucose sensor protein SLC5A4", "aln": "MASTVSPSTIAETPEPPPLSDHIRNAADISVIVIYF-LVVMAVGLWAMLKTNRGTIGGFFLAGRDMAWWPMGASLFASNIGSNHYVGLAGTGAASGVATVTFEWTSSVMLLILGWIFVPIYIK---SGVMTMPEYLKKRFGGERLQVYLSILSLFICVVLLISADIFAGAIFIKLALGLDLYLAIFILLAMTAVYTTTGGLASVIYTDTLQTIIMLIGSFILMGFAFNEVGGYESFTEKYVNATPSVVEGDNLTISASCYTPRADSFHIFRDAVTGDIPWPGIIFGMPITALWYWCTNQVIVQRCLCGKDMSHVKAACIMCAYLKLLPMFLMVMPGMISRILYTDMVACVVPSECVKHCGVDVGCTNYAYPTMVLELMPQGLRGLMLSVMLASLMSSLTSIFNSASTLFTIDLYTK-MRKQASEKELLIAGRIFVLLLTVVSIVWVPLVQVSQNGQLIHYTESISSYLGPPIAAVFVLAIFCKRVNEQGAFWG--LMVGLAMGLIRMITEFAYGTGSCLAPSNCPKIICGVHYLYFSIVLFFGSMLVTLG-ISLLTKPIPDVHLYRLCWVLRNSTEERIDIDAEE-KSQEETDDGVEEDYPEKSRGCLKKAYDLFCGLQ-KGPKLTKEEEEALSKKLTDTSERPSWR---------------------------------------TIVNINAILLLAVVVFIHGYYA-----------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P33413-1", "uniprot_id": "DUR3_YEAST", "id": "P33413-1", "name": "Urea active transporter", "aln": "-----------MGEFKPPLPQGAGYAIVLGLGAVFAGMMVLTTYLLKRYQKEIITAEEFTTAGRSVKTGLVAAAVVSSWIWCSTLLTSSTKEYADGIFGG-YAYAAGACFQIIAFAILAIKTKQMAPNAHTYLELVRTRYG--KIGHGCYLFYAIATNILVTSMLLTSGSAVFSDLTGMNTIASCFLLPVGVVVYTLFGGIKATFLTDYMHTCVIIIIVLVFAFKVYATSDVLGSPGKVYD----LVREAAKRHPVDGNYQGEYMTMTSKSAGILLIINLIG-NFGTVFLDNGYWN-------KAISASPAASLKAYAIGGLAWFAVPSLISLTMGLACLAVETSPNFPTYPDPLTSFQANSG----LVLPAAAIAIMGKGGAVASLLMIFMAVTSAMSAELIAVSSVFTYDIYREYIDPRASGKKLIYTSHVACIFFGLAMSGFS--VGLYYGGISMGYIYEMMGIIISSAVLPVVLTLCSKDMNLVAAVVSPILGTGLAIMSWLVCTKSLYKELTVDTTFMDYPMLTGNLVALLSPAIFIPILTYVFKPQNFDWEKMKDITRVDETAELVQADPDIQLYDAEANDKEQEEETNSLVSDSEKNDVRVNNEKLIEPNLGVVISNAIFQEDDTQLQNELDEEQRELARGLKIAYFLCVFFALAFLVVWPMPMYGSKYIFSKKFFTGWVVVMIIWLFFSAFAVCIYPLWEGRHGIYTTLRGLYWDLSGQTYKLREWQNSNPQDLHVVTSQISARAHRQSSHFGQVDEII", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * :. * :.: .:: ::*::. * :.: * * **:.: :.*::.:* * .. : : . *.*: : : . ::.: ::.* * ... * * ::.*:* :: :: : : * : :*: .:. *:: : *:* . ...** **: :.: ** ::* :::: ::: .: . * : * * *. : * . :: : * * ** : ** :.:... : :** .* :* :: : *: . : *. . *. . . . *: .: :* .* * ::: :: *:::: : :.*::** *:* : : :** ::*: :.:: :.: : : .* : * .. . : .. .:*:: * :* .*. . * .**.: : :: * : . :: * :: :*: : : .: : : *: * : : *** ...:* . .*:. :.. : .* .: :*: : :: * .:: * :: * ::: ...* :: : ", "identical_positions": 87, "similar_positions": 223, "identity": "11.34%" }, { "cls_id": "homologset.agr.MGI:1890480", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q925R7-1", "uniprot_id": "GLT10_RAT", "id": "Q925R7-1", "name": "Polypeptide N-acetylgalactosaminyltransferase 10", "aln": "MRR-KEKRLLQAVALALAALVLLPNVGLWALYR-----------ERQPDGSPGGSGAAVAPEAIQ---------------------------------------ELHSRQKKTLFLGA---EQRLKDWHNKEAIRRDAQRVGNGEQGKPYPMTDAERVDQAYR---ENGFNIYVSDKISLNRSLPDIRHPNCNSKLYLETLPNTSIIIPFHNEGWSSLLRTVHSVLNRSPPELVAEIVLVDDFSDREHLKKPLEDYMAL-FPSVRILRTKKREGLIRTRMLGASAATGDVITFLDSHCEANVNWLPPLLDRIARNRKTIVCPMIDVIDHDDFRYETQAGDAMRGAFDWEMYYKRIPIPPELQKADPSDPFESPVMAGGLFAVDRKWFWELGGYDPGLEIWGGEQYEISFKVWMCGGRMEDIPCSRVGHIYRKYVPYKVP--AGVSLARNLKRVAEVWMDEYAEYIYQRRP-EYRHLSAGDVVAQKKLRGSLNCKSFKWFMTKIAWDLPKFYPPVEPPAAAWGEIRNVG-TGLCTDTKHGTLGSPLRLETCIRGRGEAAWNSMQVFTFTWREDIRPGDPQHTKKFCFDAVSHTS--PVTLYDCHSMKGNQLWKYR-KDKTLYHPVSG-SCMDCSESDHRIFMNTCNPSSLTQQWLFEHTNSTVLENFNRN-----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q6P9S7-1", "uniprot_id": "GLT10_MOUSE", "id": "Q6P9S7-1", "name": "Polypeptide N-acetylgalactosaminyltransferase 10", "aln": "MRR-KEKRLLQAVALALAALVLLPNVGLWALYR-----------ERQPDGSPGGLGAAVAPAAVQ---------------------------------------ELHSRQKKTFFLGA---EQRLKDWHNKEAIRRDAQRVGYGEQGKPYPMTDAERVDQAYR---ENGFNIYVSDKISLNRSLPDIRHPNCNSKLYLETLPNTSIIIPFHNEGWSSLLRTVHSVLNRSPPELVAEIVLVDDFSDREHLKKPLEDYMAL-FPSVRILRTKKREGLIRTRMLGASAATGDVVTFLDSHCEANVNWLPPLLDRIARNRKTIVCPMIDVIDHDDFRYETQAGDAMRGAFDWEMYYKRIPIPPELQKADPSDPFESPVMAGGLFAVDRKWFWELGGYDPGLEIWGGEQYEISFKVWMCGGRMEDIPCSRVGHIYRKYVPYKVP--AGVSLARNLKRVAEVWMDEYAEYIYQRRP-EYRHLSAGDVVAQKKLRVSLNCKSFKWFMTKIAWDLPKFYPPVEPPAAAWGEIRNVG-TGLCTDTKLGTLGSPLRLETCIRGRGEAAWNSMQVFTFTWREDIRPGDPQHTKKFCFDAVSHTS--PVTLYDCHSMKGNQLWKYR-KDKTLYHPVSG-SCMDCSESDHRVFMNTCNPSSLTQQWLFEHTNSTVLENFNKN-----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q86SR1-1", "uniprot_id": "GLT10_HUMAN", "id": "Q86SR1-1", "name": "Polypeptide N-acetylgalactosaminyltransferase 10", "aln": "MRR-KEKRLLQAVALVLAALVLLPNVGLWALYR-----------ERQPDGTPGGSGAAVAPAAGQ---------------------------------------GSHSRQKKTFFLGD---GQKLKDWHDKEAIRRDAQRVGNGEQGRPYPMTDAERVDQAYR---ENGFNIYVSDKISLNRSLPDIRHPNCNSKRYLETLPNTSIIIPFHNEGWSSLLRTVHSVLNRSPPELVAEIVLVDDFSDREHLKKPLEDYMAL-FPSVRILRTKKREGLIRTRMLGASVATGDVITFLDSHCEANVNWLPPLLDRIARNRKTIVCPMIDVIDHDDFRYETQAGDAMRGAFDWEMYYKRIPIPPELQKADPSDPFESPVMAGGLFAVDRKWFWELGGYDPGLEIWGGEQYEISFKVWMCGGRMEDIPCSRVGHIYRKYVPYKVP--AGVSLARNLKRVAEVWMDEYAEYIYQRRP-EYRHLSAGDVAVQKKLRSSLNCKSFKWFMTKIAWDLPKFYPPVEPPAAAWGEIRNVG-TGLCADTKHGALGSPLRLEGCVRGRGEAAWNNMQVFTFTWREDIRPGDPQHTKKFCFDAISHTS--PVTLYDCHSMKGNQLWKYR-KDKTLYHPVSG-SCMDCSESDHRIFMNTCNPSSLTQQWLFEHTNSTVLEKFNRN-----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6WV16-1", "uniprot_id": "GALT6_DROME", "id": "Q6WV16-1", "name": "N-acetylgalactosaminyltransferase 6", "aln": "MRRPNLKWIVKASLLLLISLTLFVLITSWISSTPYTNKPVHHGVEPVPEKAGLSGDVKVKVPAIKQPEPQKPQEPDFEEDPELQKIDEPEPVEEEVDNPHPADDEPQQQPQEELQMAAPADASVKKDWHDYTFMEKDAKRVGLGEGGKASTLDDESQRDLEKRMSLENGFNALLSDSISVNRSVPDIRHPLCRKKEYVAKLPTVSVIIIFYNEYLSVLMRSVHSLINRSPPELMKEIILVDDHSDREYLGKELETYIAEHFKWVRVVRLPRRTGLIGARAAGARNATAEVLIFLDSHVEANYNWLPPLLEPIALNKRTAVCPFIDVIDHTNFHYRAQD-EGARGAFDWEFFYKRLPLLPEDLKH-PADPFKSPIMAGGLFAISREFFWELGGYDEGLDIWGGEQYELSFKIWMCGGEMYDAPCSRIGHIYRGPRNHQPSPRKGDYLHKNYKRVAEVWMDEYKNYLYSHGDGLYESVDPGDLTEQKAIRTKLNCKSFKWFMEEVAFDLMKTYPPVDPPSYAMGALQNVGNQNLCLDTLGRKKHNKMGMYACADNIKTPQR--TQFWELSWKRDLR----LRRKKECLDVQIWDANAPVWLWDCHSQGGNQYWYYDYRHKQLKHGTEGRRCLELLPFSQEVVANKCDTDNRFQQWNFGSFNKTALDNYSQDLVLSL", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*** : * :::* * * :*.*: : * * *: : . .. * * : :.: :: : :. . ****: :.:**:*** ** *:. .: * .: * * ***** :**.**:***:****** *..* *: .**..*:** *:** * *:*:***::*******: **:****.****:* * ** *:* * **::* :* *** :* ** **.:*: ***** *** *******: ** *::* ***:****** :*:*.:* :. *******::***:*: ** * *:***:**:*******:.*::******** **:********:***:*****.* * ****:***** :: . * * :* *********** :*:*.: *. :..**:. ** :* .********** ::*:** * ****:**: * * ::*** .** ** . : : * . . *.: ::*:.*:* : ** *:*. : ** *:**** *** * * :.* * * ..* *:: .:.:. *.*:... *** * *.*.*:::.:: ", "identical_positions": 283, "similar_positions": 153, "identity": "41.99%" }, { "cls_id": "homologset.agr.MGI:1890494", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q91XQ6-1", "uniprot_id": "LAP4B_MOUSE", "id": "Q91XQ6-1", "name": "Lysosomal-associated transmembrane protein 4B", "aln": "-------------------------------------------------------------------------------------------MKMVAPWTRFYSHSCCLCCHVRTGTILLGVWYLIINAVVLLILLSALADPNQYHFSGSELGGEFEFMDDANMCIAIAISLLMILICAMATYGAYKQHAAWIIPFFCYQIFDFALNTLVAITVLVYPNSIQEYIRQLPPSFPYRDDIMSVNPTCLVLIILLFIGILLTLKGYLISCVWSCYRYINGRNSSDVLVYVTSNDTTVLLPPYDDATAVPSTAKEPPPPYVSA", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q5U1W4-1", "uniprot_id": "LAP4B_RAT", "id": "Q5U1W4-1", "name": "Lysosomal-associated transmembrane protein 4B", "aln": "-------------------------------------------------------------------------------------------MKMVAPWTRFYSHSCCLCCHVRTGTILLGIWYLIINAVVLLILLSALADPDQYHFSGSELGGEFEFMDDANMCIAIAISLLMILICAMATYGAYKQHAAWIIPFFCYQIFDFALNTLVAITVLVYPNSIQEYIRQLPPSFPYRDDIMSVNPTCLVLVILLFIGIILTFKGYLISCVWSCYRYINGRNSSDVLVYVTSNDTTVLLPPYDDATAVTGTAKEPPPPYVSA", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q86VI4-3", "uniprot_id": "LAP4B_HUMAN", "id": "Q86VI4-3", "name": "Lysosomal-associated transmembrane protein 4B", "aln": "MTSRTRVTWPSPPRPLPVPAAAAVAFGAKGTDPAEARSSRGIEEAGPRAHGRAGREPERRRSRQQRRGGLQARRSTLLKTCARARATAPGAMKMVAPWTRFYSNSCCLCCHVRTGTILLGVWYLIINAVVLLILLSALADPDQYNFSSSELGGDFEFMDDANMCIAIAISLLMILICAMATYGAYKQRAAWIIPFFCYQIFDFALNMLVAITVLIYPNSIQEYIRQLPPNFPYRDDVMSVNPTCLVLIILLFISIILTFKGYLISCVWNCYRYINGRNSSDVLVYVTSNDTTVLLPPYDDAT-VNGAAKEPPPPYVSA", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ************:****************:********************:**:**.*****:*********************************:****************** *******:**************.******:**********:*****.*:**:*********.********************************* * .:***********", "identical_positions": 207, "similar_positions": 17, "identity": "65.09%" }, { "cls_id": "homologset.agr.MGI:1890495", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8VEB6-1", "uniprot_id": "RNZ1_MOUSE", "id": "Q8VEB6-1", "name": "Zinc phosphodiesterase ELAC protein 1", "aln": "MSMDVTFLGTGAAYPSPTRGASAVVLRCEGECWLFDCGEGTQTQLMKSQLKAGRITKIFITHLHGDHFFGLPGLLCTISLQSGSVVARQPIEIYGPVGLRDFIWRTMELSHTELVFPYVVHELVPTADQCPVEELREFAHMDETDSSPKG-QGRTILLDAEENSYCLVDDEQFVVKAFRLFHRIPSFGFSVVEKKRAGKLNAQKLRDLGVPPGPAYGKLKNGISVVLDNGVTISPQDVLKKPMVGRKVCILGDCSGVVGDGGVKLCFEADLLIHEATLDDSQMDKAREHGHSTPQMAAAFAKLCRAKRLVLTHFSQRYKPTALAREGEADGIAELRKQAEAVLELQEVTLAEDFMVIGIPIKK", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D3ZB91-1", "uniprot_id": "D3ZB91_RAT", "id": "D3ZB91-1", "name": "Zinc phosphodiesterase ELAC protein 1", "aln": "MSMDVTFLGTGAAYPSPTRGASAVVLRCEGECWLFDCGEGTQTQLMKSQLKAGRITKIFITHLHGDHFFGLPGLLCTISLQSGSVVSRQPIEIYGPVGLRDFIWRTMELSHTELVFPYVVHELVPTADQCPVEELRESAQMDEADSSPKG-QGRTILLDAEENSYCLVDDEQFVVKAFRLFHRIPSFGFSVVEKKRTGKLSAQKLRDLGVPPGPAYGKLKNGISVVLDNGVTISPQDVLKKPMVGRKVCILGDCSGVVGDGGVKLCFEADLLIHEATLDDSQMDKAKEHGHSTPQMAATFAKLCRAKRLVLTHFSQRYKPTALAREGEADGITELKKQAESVLELQEVTLAEDFMVIGIPIKK", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9H777-1", "uniprot_id": "RNZ1_HUMAN", "id": "Q9H777-1", "name": "Zinc phosphodiesterase ELAC protein 1", "aln": "MSMDVTFLGTGAAYPSPTRGASAVVLRCEGECWLFDCGEGTQTQLMKSQLKAGRITKIFITHLHGDHFFGLPGLLCTISLQSGSMVSKQPIEIYGPVGLRDFIWRTMELSHTELVFHYVVHELVPTADQCPAEELKEFAHVNRADSPPKEEQGRTILLDSEENSYLLFDDEQFVVKAFRLFHRIPSFGFSVVEKKRPGKLNAQKLKDLGVPPGPAYGKLKNGISVVLENGVTISPQDVLKKPIVGRKICILGDCSGVVGDGGVKLCFEADLLIHEATLDDAQMDKAKEHGHSTPQMAATFAKLCRAKRLVLTHFSQRYKPVALAREGETDGIAELKKQAESVLDLQEVTLAEDFMVISIPIKK", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "************************************************************************************:*::**************************** **************.***:* *:::.:**.** ********:***** *.****************************.***.****:*********************:**************:****:********************************:*****:***********:*********************.*******:***:**:****:**:*************.*****", "identical_positions": 329, "similar_positions": 29, "identity": "90.63%" }, { "cls_id": "homologset.agr.MGI:1890496", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8CGS5-1", "uniprot_id": "RNZ2_RAT", "id": "Q8CGS5-1", "name": "Zinc phosphodiesterase ELAC protein 2", "aln": "MWALRSLLRPLGLRTMSQG-------SARRPRPPKDPLRHLRTREKRGPGWGPGGPNTVYLQVVAAGGRDAAAALYVFSEYNRYLFN--CGEGVQRLMQEHKLKVARLDNIFLT-RMHWSNVGGLCGMILTLKETGLPKCVLSGPPQLEKYLEAIKIFSGPLKGIDL-AVRPHSAPEYKDETMTVYQVPIHSERRCGEQEPSRSPKRSPNRLSPKQSSS--DPGSAENGQCLPEGSSAGVNGKAWGRDPSLVVAFVCKLHLRKGNFLVLKAKELGLPVGTAAIAPIIAAVKDGKSITYE-GREIAAEELCTPPDPGLVFIVVECPDEGFIQPICEN---------DTFQRYQ-GEADAPVAVVVHIAPESVLIDSRYQQWMER-FGPDTQHLILNENCPSVHN----LRSHKIQTQLSLIHPDIFPQLTSFHSKE--------------EGSTFSLPTVRG--------ECLLKYHVRPKREWQRDTTLDCNTDEFIAEALELPNFQESVEEYRKNMQASPA---PAEKRSQYPEIVFLGTGSAIPMKIRNVSSTLVNLSP--------DKSVLLDCGEGTFGQLCRHYG-QQIDRVLCNLTAVFVSHLHADHHTGLLNILLQREHALA-------------SLGKPFQPLLVVAPTQLRAWLQQY-------------------HNQCQEILHHISMIPAKCLQKGAEVPSPPVERLISLLLETCDLQEFQTCLVRHCKHAFGCALVHSSG-------WKVVYSGDTMP--CEALVQMGKDATLLIHEATLEDGLEEEAVEKTHSTTSQAIGVGMRMNAEFIMLNHFSQRYAKIP-LFSPD--FNEKVGIAFDHMKVCFGDFPTVPKLIPPLKALFADDIEEMVERREKRELRLVRAALLT-QQADSSEDREPHQKRAHSEEPHSPQSKKVRAQ-------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q80Y81-1", "uniprot_id": "RNZ2_MOUSE", "id": "Q80Y81-1", "name": "Zinc phosphodiesterase ELAC protein 2", "aln": "MWALRSLLRPLGLRTMSQG-------SARRPRPSKDPLRHLRTREKRGP--GPGGPNTVYLQVVAAGGRDAGAALYVFSEYNRYLFN--CGEGVQRLMQEHKLKVARLDNIFLT-RMHWSNVGGLCGMILTLKETGLPKCVLSGPPQLEKYLEAIKIFSGPLKGIEL-AVRPHSAPEYKDETMTVYQVPIHSERRCGKQQPSQSPRTSPNRLSPKQSS---DSGSAENGQCPPEDSSAGANRKAWGRDPSLVVAFVCKLHLRKGNFLVLKAKELGLPVGTAAIAPIIAAVKDGKSITYE-GREIAAEELCTPPDPGLVFIVVECPDEGFILPICEN---------DTFKRYQ-AEADAPVALVVHIAPESVLIDSRYQQWMER-FGPDTQHLILNENCPSVHN----LRSHKIQTQLSLIHPDIFPQLTSFYSKE--------------EGSTLSVPTVRG--------ECLLKYQLRPKREWQRDTTLDCNTDEFIAEALELPSFQESVEEYRKNVQENPA---PAEKRSQYPEIVFLGTGSAIPMKIRNVSSTLVNLSP--------DKSVLLDCGEGTFGQLCRHYG-QQIDRVLCSLTAVFVSHLHADHHTGLLNILLQREHALA-------------SLGKPFQPLLVVAPTQLRAWLQQY-------------------HNHCQEILHHVSMIPAKCLQKGAEVSNTTLERLISLLLETCDLEEFQTCLVRHCKHAFGCALVHSSG-------WKVVYSGDTMP--CEALVQMGKDATLLIHEATLEDGLEEEAVEKTHSTTSQAINVGMRMNAEFIMLNHFSQRYAKIP-LFSPD--FNEKVGIAFDHMKVCFGDFPTVPKLIPPLKALFAGDIEEMVERREKRELRLVRAALLT-QQADSPEDREPQQKRAHTDEPHSPQSKKESVANTLGARV", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9BQ52-1", "uniprot_id": "RNZ2_HUMAN", "id": "Q9BQ52-1", "name": "Zinc phosphodiesterase ELAC protein 2", "aln": "MWALCSLLRSAAGRTMSQGRT-ISQAPARRERPRKDPLRHLRTREKRGPSGCSGGPNTVYLQVVAAGSRDSGAALYVFSEFNRYLFN--CGEGVQRLMQEHKLKVARLDNIFLT-RMHWSNVGGLSGMILTLKETGLPKCVLSGPPQLEKYLEAIKIFSGPLKGIEL-AVRPHSAPEYEDETMTVYQIPIHSEQRRGKHQPWQSPERPLSRLSPERSS---DSESNENEPHLP----HGVSQRRGVRDSSLVVAFICKLHLKRGNFLVLKAKEMGLPVGTAAIAPIIAAVKDGKSITHE-GREILAEELCTPPDPGAAFVVVECPDESFIQPICEN---------ATFQRYQ-GKADAPVALVVHMAPASVLVDSRYQQWMER-FGPDTQHLVLNENCASVHN----LRSHKIQTQLNLIHPDIFPLLTSFRCKK--------------EGPTLSVPMVQG--------ECLLKYQLRPRREWQRDAIITCNPEEFIVEALQLPNFQQSVQEYRRSAQDGPA---PAEKRSQYPEIIFLGTGSAIPMKIRNVSATLVNISP--------DTSLLLDCGEGTFGQLCRHYG-DQVDRVLGTLAAVFVSHLHADHHTGLPSILLQRERALA-------------SLGKPLHPLLVVAPNQLKAWLQQY-------------------HNQCQEVLHHISMIPAKCLQEGAEISSPAVERLISSLLRTCDLEEFQTCLVRHCKHAFGCALVHTSG-------WKVVYSGDTMP--CEALVRMGKDATLLIHEATLEDGLEEEAVEKTHSTTSQAISVGMRMNAEFIMLNHFSQRYAKVP-LFSPN--FSEKVGVAFDHMKVCFGDFPTMPKLIPPLKALFAGDIEEMEERREKRELRQVRAALLSRELAGGLEDGEPQQKRAHTEE---PQAKKVRAQ-------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F1QHE2-1", "uniprot_id": "F1QHE2_DANRE", "id": "F1QHE2-1", "name": "Zinc phosphodiesterase ELAC protein 2", "aln": "--MLARLRRSLSVFLMDAH-------TSGRSKTLKETRRPLKTRDNRRQ-ADNHGPANVYVQVVGAGSRDNGASLYVFSEFNRYLFN--CGEGTQRLMQEHKLKIARLDNIFLT-RMSWDTVGGLSGMILTLKDTGVHQCVLSGPPQLDRFLKAIKVFSGQLEDIKL-AVRPYTEPQYKDETMTVSQIPLFSDR---KAESGRCSPRSFSPHSSQQGVLRILEDQEENQSIHTRRRSTSPEGKEVTRDPSLVVAYVCKLHSRTGNFLVMKAKEMGLPVGTAAIGPIIKALKSGKTVTHE-GKEIRPEELCTPADPGPVFIVVDCPSEDFIKPLCSN---------PILKRFQSGGSEDSAALVVHMTPEAVLNTQEYKSWMER-FPSSTEHLLMNEQTFTPHN----ARSHKLQTQLNLIHPHIFPQLKLYRTKD--------------PPASLHVPNVRA--------ECLLKFQLRPKLEWQRDAIPSCDSEEFVKEAAKVPNFLAEVEECRK-FQAAAS---VSTSGEKFPEIVFLGTGSSLPMKIRNVSGTLVNISS--------SQSLLLDCGEGTFSQMCRHYG-DDVDEMLSKLSTIFVSHLHADHHTGLIQLLLERERALN-------------SLGKALSPVYLIAPIQIMSWLNQY-------------------HDHCQQILSQINIIPSRLLCDGTESPKVKTKSFIQAVLKKNELSKFQTCFARHCKNAFACSLTHESG-------WKLVFSGDTMP--CDALVDIGKNATLLIHEATLEDGMEDEAFEKRHSTTSQAIGIGMKMNAGFIVLNHFSQRYAKIP-LFSDD--FDNKVGISFDHMRIQFGDFPMLPRLIRPLKALFAEEIEEMEERREKRELKKSFEPPANGESGKSKAAKREQED--HNQE---NANKRLKAN-------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q8MKW7-1", "uniprot_id": "RNZ_DROME", "id": "Q8MKW7-1", "name": "Ribonuclease Z, mitochondrial", "aln": "MYLVKSAGSPIYRTLRTLTTSNLMAATIASAKDPLTGPRYEREPNVLRKKLASVVPGTVNLQVLGSGANGAPAAVYLFTDQARYLFN--CGEGTQRLAHEHKTRLSRLEQIFLT-QNTWASCGGLPGLTLTIQDAGVRDIGLHGPPHLGSMLQSMRRFVVLKNLQVR-PNDCSEGACFEDSILKVDSLPLINSE----------------------------------------------------DPTKSVINYICQLKPRAGALNLVKCVEQGVPP-----GPLLGQLKNGNDITLPDGKVVRSVDVTEASETALSFVFLDVPSENYLPALLTH---------GKRLKKLGEEKLTEVALVVHFTPYHISSRQVYKDFVVESFSSEAQHIYLSSPLNQFSGY---AAAHRIQHQLHQLAPQVFPLLGEQLSCQSQTLSLNLKKTKLDEADSEDKANAKANETEEQGVVAMTNYHLRPRKGLDRTLESKLTPEEYVKETHAVPGFLELLAKFKEEYSFPDN---SADS---YPKIIFLGTGSCIPNKTRNVSSILIRTAI--------DAYVLLDCGEGTYGQIVRLYGHEKGQLILRQLQAIYVSHLHADHHIGLIGLLRERR-----------------QLKPRADPLILLAPRQIEPWLEFY-------------------NRQIETVEDAYTLVGNGELLASP---------LSGEQVERLGITSISTCLVRHCPNSFGISLTLAAKHNSEP--VKITYSGDTMP--CQDLIDLGRDSTVLIHEATMEDDLEEEARLKTHSTVSQAIQQGRNMNARHTILTHFSQRYAKCPRLPSDE--DMQRVAIAFDNMEVTIEDLQHYHKLYPALFAMYAEYTEELEQRAVKRELKQERKRKLAET--------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P36159-1", "uniprot_id": "RNZ_YEAST", "id": "P36159-1", "name": "Ribonuclease Z", "aln": "--------------------------------------------------------MFTFIPITHPTSDTKHPLLLVQSAHGEKYFFGKIGEGSQRSLTENKIRISKLKDIFLTGELNWSDIGGLPGMILTIADQGKSNLVLHYGNDILNYIVSTWRYFVFRFGIDLNDHIMKDKEVYKDKIIAVKSFNVLKNGGEDRLGVFDSFQKGVLRSIVAKMFP---KHAPTDRYDPSSDPHLNVELPDLDAKVEVSTNYEISFSPVRGKFKVEEAIKLGVPK-----GPLFAKLTKGQTITLDNGIVVTPEQVLENERHFAKVLILDIPDDLYLNAFVEKFKDYDCAELGMVYYFLGDEVTINDNLFAFIDIFEKNNYGKVNHMISHNKISPNTISFFGSALTTLKLKALQVNNYNLPKTDRVFSKDFYDRFDTPLSRG----TSMCKSQEEPLNTIIEKDNIHIFSQNKTVTFEPFRMNEEPMKCNINGEVADFSWQEIFEEHVKPLEFPLADVDTVINNQLHVDNFNNSAEKKKHVEIITLGTGSALPSKYRNVVSTLVKVPFTDADGNTINRNIMLDAGENTLGTIHRMFSQLAVKSIFQDLKMIYLSHLHADHHLGIISVLNEWYKYNKDDETSYIYVVTPWQYHKFVNEWLVLENKEILKRIKYISCEHFINDSFVRMQTQSVPLAEFNEILKENSNQESNRKLELDRDSSYRDVDLIRQMYEDLSIEYFQTCRAIHCDWAYSNSITFRMDENNEHNTFKVSYSGDTRPNIEKFSLEIGYNSDLLIHEATLENQLLEDAVKKKHCTINEAIGVSNKMNARKLILTHFSQRYPKLPQLDNNIDVMAREFCFAFDSMIVDYEKIGEQQRIFPLLNKAFVEEKEEEEDVDDVESVQDLEVKLKKHKKN------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . : : . . . : : : . * *** ** *:* ::::*.:**** . * *** *: **: : * . * .: : : : ::*. : * .. : .. . : .: * : : :. : *:* .*:: :..*: :* * : . :: .:.:: *.: :: .: : :...: : : . . :.. :.: : ..: : : . : .* . :* . * * . . : . . :*: *****.:* * *** . *:. . . ::**.**.* . : * :. . :: * :::******** *: :* : . :: :: :: . : : . : . : :.** . ** ::. ::. *: :**** * . : :* :: :******:*: : ::* * *.* .:** . .*** :*.******.* * * . ... .:** * : .: :: * :. ** : ..:: ", "identical_positions": 108, "similar_positions": 190, "identity": "11.46%" }, { "cls_id": "homologset.agr.MGI:1890497", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9WV78-1", "uniprot_id": "PLVAP_RAT", "id": "Q9WV78-1", "name": "Plasmalemma vesicle-associated protein", "aln": "------MGLSMDRS-PYSRTGDRDRGCWYYLRYFFLFVSLIQFLIILGLVLFMIYGNVHATTESS-LRATEIRADNLYSQVVGLSAAQANLSKQLNISTLVKDTVMQQLLTTRREVERINASFRQCQ-GDLITYINYNRFIAAIILSEKQCQEQLKEGNKTCEALLFKLGEKVKTLEMEVVKEKAVCSKDKDSLLAGKRQAEMQQEACGKAREQQKQDQQVTEEQLRKVQSLCLPLDQEKFQADVLNVWRDSLVYRSLDNIGY--HYSLMP-EFSSLRRTCESLPGIMTTKVEELARGLRAGIERVTRENGELRRQKLELERAIQGEREARTRAGTEAQARETQLRTECARQTQLALEEKAALRTQRDDLERQLEARKRELEQLRTEVDVRISALDTCVKAKSLPAIQP-RLPGPPPNPPPIDPASLEEFKKRILESQRPPLVNPAVPPSG", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q91VC4-1", "uniprot_id": "PLVAP_MOUSE", "id": "Q91VC4-1", "name": "Plasmalemma vesicle-associated protein", "aln": "------MGLSMDRS-PYARTGDQQRGCWYYLRYFFLFVSLIQFLIILGLVLFMIYGNVHATTESS-LRATEIRADSLYSQVVGLSASQANLSKQLNISLLVKETVMQQLLTTRREMERINASFRQCQ-GDLITYINYNRFIAAIILSEKQCQEQLKEVNKTCEALLFKLGEKVKTLEMEVAKEKAVCSKDKESLLAGKRQTEEQLEACGKARERQQQEQQVTEENLRKVQSLCIPLDQEKFQADVLSAWRDSLIYRTLETLPY--HYQLMP-EYASLRRTCESLPGIMTTKIEELARGLRAGIERVTRENAELRRQKLELERAAQAAQEARARAGTEAQARETQLRAECARQTQLALEEKAALRAQRDNLERELEARKRELEQLRTEVDVRISALDTCVKAKSLPAVPP-RVSGPPPNPPPIDPASLEEFKKRILESQRLPVVNPAAQPSG", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9BX97-1", "uniprot_id": "PLVAP_HUMAN", "id": "Q9BX97-1", "name": "Plasmalemma vesicle-associated protein", "aln": "------MGLAMEHGGSYARAGGSSRGCWYYLRYFFLFVSLIQFLIILGLVLFMVYGNVHVSTESN-LQATERRAEGLYSQLLGLTASQSNLTKELNFTTRAKDAIMQMWLNARRDLDRINASFRQCQ-GDRVIYTNNQRYMAAIILSEKQCRDQFKDMNKSCDALLFMLNQKVKTLEVEIAKEKTICTKDKESVLLNKRVAEEQLVECVKTRELQHQERQLAKEQLQKVQALCLPLDKDKFEMDLRNLWRDSIIPRSLDNLGYNLYHPLGS-ELASIRRACDHMPSLMSSKVEELARSLRADIERVARENSDLQRQKLEAQQGLRASQEAKQKVEKEAQAREAKLQAECSRQTQLALEEKAVLRKERDNLAKELEEKKREAEQLRMELAIRNSALDTCIKTKSQPMMPVSRPMGPVPNPQPIDPASLEEFKRKILESQRPPAGIPVAPSSG", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F1Q8W5-1", "uniprot_id": "F1Q8W5_DANRE", "id": "F1Q8W5-1", "name": "", "aln": "MYKNSYSQATFGLEAKKIHKAKKGKSCGYYMRIVFFFSSLIQSLIIASLVLFLVYGQPEKTAEEKRLEDLQQAYDTLSKDHTKLRKEKADLATALKTKSGEKDAADKEITKLKTDLNISIAGSKNWQRLNSQCEANAKLKLSSTRNTPLMCPPANPNQSGEVKTLNTLLDQQKALYGILKSNFSQTVEYLKSDLDHAVKDKNEHHSQVIKLRQENKDLKSQLDVYTKKCKEDFADSLQG--IQTVTTAFLSKIDNFFTNSVTFHLTCPKQEEQMDRIRSNCSSLSRQVEDKFQSYLNNVGAKVSNIQKQSSWLEIQNEKLTSELDKCKTEAEKEASDSSKKLQDAQTTCDKQLEQLLKEQTRLRNAKDLVDTELSVKEATIISLQKG----------CTPQAKPSGFQPLGSAGQYPSTSG------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :: : . :.* **:* .*:* **** *** .****::**: . ::*.. *. : : * .: * :::*:. *: . *:: : . : ::: *. :: * : * : ::: : * : . .:* *.:: : : . *..: : : : * *: ::: :. . :* : : : . : ..: :.: : : :* *. :. : *.:. ..: * :..: ::.. *. *: : : : .::. : . :: * :* : *:*:: ** :* : :*. :: .*: * . . . * *.. ", "identical_positions": 54, "similar_positions": 134, "identity": "11.97%" }, { "cls_id": "homologset.agr.MGI:1890498", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I6G3L4-1", "uniprot_id": "A0A8I6G3L4_RAT", "id": "A0A8I6G3L4-1", "name": "", "aln": "--------MMLPR--------------TWAVETE------QLLTPNPGYGTQ-------------AGTSP--------APTTP------PEEEDLRRRLKYFFMSPCDKFRAKGRKPCKLMLQVVKILVVTVQLILFGLSNQLVVTFREENTIAFRHLFLLGYSDG--------SDDTFAAYTREQLYQAIFYAVDQYLTLPEISLGRYAYVRGGGGPWANGSALALCQRYYHRGHVDPANDTFDIDPRVVTDCIQVDPPDRPPDIPSEDLDFLDGSTSYKNITLKFHKLINVTIHFQLKTINLQSLIN-NEIPDCYTFSILITFDNKAHSGRIPIRLETQTHIQECKHPS---VSRHGDNSFRLLFDVVVILTCSLSFLLCARSLLRGFLLQNEFVVFMWRRRGREISLWERLEFVNGWYILLVTSDVLTISGTIMKIGIEAKNLAS--YDVCSILLGTSTLLVWVGVIRYLTFFHKYNILIATLRVALPSVMRFCCCVAVIYLGYCFCGWIVLGPYHVKFRSLSMVSECLFSLINGDDMFVTFAAMQAQQGRSSLVWLFSQLYLYSFISLFIYMVLSLFIALITGAYDTIKHPGGTGTEKSELQAYIEQCQDSPTSG--------KFRRGS-GSTCSLLCCCGRNSPEDHSLLVN-----------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q99J21-1", "uniprot_id": "MCLN1_MOUSE", "id": "Q99J21-1", "name": "Mucolipin-1", "aln": "--------MATPAG-------------RRASETE------RLLTPNPGYGTQ-------------VGTSP--------APTTP------TEEEDLRRRLKYFFMSPCDKFRAKGRKPCKLMLQVVKILVVTVQLILFGLSNQLVVTFREENTIAFRHLFLLGYSDG--------SDDTFAAYTQEQLYQAIFYAVDQYLILPEISLGRYAYVRGGGGPWANGSALALCQRYYHRGHVDPANDTFDIDPRVVTDCIQVDPPDRPPDIPSEDLDFLDGSASYKNLTLKFHKLINVTIHFQLKTINLQSLIN-NEIPDCYTFSILITFDNKAHSGRIPIRLETKTHIQECKHPS---VSRHGDNSFRLLFDVVVILTCSLSFLLCARSLLRGFLLQNEFVVFMWRRRGREISLWERLEFVNGWYILLVTSDVLTISGTVMKIGIEAKNLAS--YDVCSILLGTSTLLVWVGVIRYLTFFHKYNILIATLRVALPSVMRFCCCVAVIYLGYCFCGWIVLGPYHVKFRSLSMVSECLFSLINGDDMFVTFAAMQAQQGHSSLVWLFSQLYLYSFISLFIYMVLSLFIALITGAYDTIKHPGGTGTEKSELQAYIEQCQDSPTSG--------KFRRGS-GSACSLFCCCGRDSPEDHSLLVN-----------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9GZU1-1", "uniprot_id": "MCLN1_HUMAN", "id": "Q9GZU1-1", "name": "Mucolipin-1", "aln": "--------MTAPAG-------------PRGSETE------RLLTPNPGYGTQ-------------AGPSP--------APPTP------PEEEDLRRRLKYFFMSPCDKFRAKGRKPCKLMLQVVKILVVTVQLILFGLSNQLAVTFREENTIAFRHLFLLGYSDG--------ADDTFAAYTREQLYQAIFHAVDQYLALPDVSLGRYAYVRGGGDPWTNGSGLALCQRYYHRGHVDPANDTFDIDPMVVTDCIQVDPPERPPPPPSDDLTLLESSSSYKNLTLKFHKLVNVTIHFRLKTINLQSLIN-NEIPDCYTFSVLITFDNKAHSGRIPISLETQAHIQECKHPS---VFQHGDNSFRLLFDVVVILTCSLSFLLCARSLLRGFLLQNEFVGFMWRQRGRVISLWERLEFVNGWYILLVTSDVLTISGTIMKIGIEAKNLAS--YDVCSILLGTSTLLVWVGVIRYLTFFHNYNILIATLRVALPSVMRFCCCVAVIYLGYCFCGWIVLGPYHVKFRSLSMVSECLFSLINGDDMFVTFAAMQAQQGRSSLVWLFSQLYLYSFISLFIYMVLSLFIALITGAYDTIKHPGGAGAEESELQAYIAQCQDSPTSG--------KFRRGS-GSACSLLCCCGRDPSEEHSLLVN-----------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A2BGV1-1", "uniprot_id": "A2BGV1_DANRE", "id": "A2BGV1-1", "name": "", "aln": "--------MAAVDPNK---------LDHISSEED------RLLYPVAHYGSNDCM-------DEYSKPRP--------TPVTDGWIGADPEEEELRRKLKYFFMSPCEKYQAKGRKPFKLILQILKIVIVTAQLVLFGLSNEMAVMFKEENTASFKHLFLKDYAD---------SDDALAVYTQSDVYDHMFYAVEQYLSLADTTVGQYAYVYGVG---VNGSALSLCQQYYKKGRIDPANDTFIIDPLVVTDCIGVNPLSTPTAAGTG--------RDYRNFTLKFHKLINVTIQFQLKAINLQTIIH-NEIPDCYTFLITILLDNKAHSGKVRISLDNKASIKECRDPS---VSGHPDSNARVLFDLAVALVCVFSLLLCGRSIIRGIILQNEFVKYFKTSLKRHVCWGDRMEFINGWYILLIISDLLTITGSIIKIGIELKNLSS--YDECGILLGTSTLLVWVGVIRYLTFFQKYNILIVTLQAAFPNVIRFCCCVAVIYLGYCFCGWIVLGPYHVKFRSLSSVSECLFSLINGDDMFVTFSGMQES---SMLVWVFSQVYLYTFISLFIYMVLSLFIALITGAYETIKHQTQEPIHITDLHAFIAECTDTPCSG--------KFRGIE-TSPCSFFCCCDRTTTYEDVLLVN-----------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VW35-1", "uniprot_id": "Q9VW35_DROME", "id": "Q9VW35-1", "name": "", "aln": "MQSYGPGAQTAPAVKRRTDSYEAAQQQQQSPESDEEYVNTRILRRQVQLQSTPVAPVVPMPISAGSGTAPPSVDGREEQPEFPGSSAASYQEERMRRKLQFFFMNPIEKWQAKRKFPYKFVVQIVKIFLVTMQLCLFAHSRYNHINYTGDNRFAFSHLFLRGWDSSREVESYPPAVGPFALYLKSEFFDTVQYAVNGYANVSR-SIGPYDYPTPNN----TMPPLKLCLQNYREGTIFGFNESYIFDPHIDEVCERLPPNVTTIGVENY--------LRQRDVEVNFASLVSAQLTFKIKTVNFKANGGPLSAPDCFRFDISITFNNRDHDGQMLLSLDAEATRLKCHGATDFISDANFDSMLRSVLNIFVLLTCALSFALCTRALWRAYLLRCTTVNFFRSQFGKELSFDGRLEFVNFWYIMIIFNDVLLIIGSALKEQIEGRYLVVDQWDTCSLFLGIGNLLVWFGVLRYLGFFKTYNVVILTLKKAAPKILRFLIAALLIYAGFVFCGWLILGPYHMKFRSLATTSECLFALINGDDMFATFATLSSK---ATWLWWFCQIYLYSFISLYIYVVLSLFIAVIMDAYDTIKAYYKDGFPTTDLKAFVGTRTAEDISSGVFMTDLDDFDQTSFLDVVKSICCCGRCGRHQEPAQPNSGYTSLSSIMK", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . * : ::* : . * * :** :**:*::***.* :*::** : * *:::*::**.:** ** **. *. : : :* :* **** .: . : ..:* * :.:.:: : :**: * :. ::* * * . . . * ** : *:.* : *::: :** : * : * . . ::. ::* .*:.. : *::*::*::: . ***: * : * ::*: *.*:: : *: :: :*: .: : *. * :::: * *.* :*: ** *:: *. :*: * :: : :. *:**:* ***::: .*:* * *: :* ** : * :* *.::** ..****.**:*** **:.**::* **: * *.::** .. :** *: ****::*****:*****: .*****:********.**: :. . : :* *.*:***:****:**:*******:* .**:*** ::*:*:: *. .* . . . :***.* :. * ", "identical_positions": 184, "similar_positions": 182, "identity": "27.54%" }, { "cls_id": "homologset.agr.MGI:1890500", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I5ZXW7-1", "uniprot_id": "A0A8I5ZXW7_RAT", "id": "A0A8I5ZXW7-1", "name": "", "aln": "-----------MPYSRISLRNSLDGGFLLSDDSSLCPVDLKLPSTPIGPLKTMLLVDREMANP-EVVVSSCSSHQDESPCTFYPSSSQSEQLLLEDQMRRKLKFFFMNPCEKFWARGRKPWKLAIQILKIAMVTIQLVLFGLSNQMVVAFKEENTIAFKHLFLKGYMDRM--------DDTYAVYTQNDVYDQIIFAVTRYLQLRNISVGNHAYENKGTKQSAMAVCQHFYRQGTICPGNDTFDIDPEVETDCFLIEPEEAFHMGTPGENKLNLTLDFHRLLTVELQFKLKAINLQTVR-HQELPDCYDFTLTITFDNKAHSGRIKISLDNDISIRECK-DWHVSGSIQKNTHYMMIFDAFVILTCLSSLVLCARSVIRGLQLQQEFVNFFLLHYKKEVSASDQMEFINGWYIMIIVSDILTIVGSILKMEIQAK--SLTSYDVCSILLGTSTMLVWLGVIRYLGFFAKYN----------LLILTLQAALPNVIRFCCCAAMIYLGYCFCGWIVLGPYHEKFRSLNKVSECLFSLINGDDMFSTFAKMQQKSYLVWLFSRVYLYSFISLFIYMILSLFIALITDTYETIKHYQQDGFPETELRKFIAECKDLPNSG---KYRLEDDPPGS------LFCCCKK----------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8R4F0-1", "uniprot_id": "MCLN3_MOUSE", "id": "Q8R4F0-1", "name": "Mucolipin-3", "aln": "-----------------------------------------------------------MANP-EVLVSSCRARQDESPCTFHPSSSPSEQLLLEDQMRRKLKFFFMNPCEKFWARGRKPWKLAIQILKIAMVTIQLVLFGLSNQMVVAFKEENTIAFKHLFLKGYMDRM--------DDTYAVYTQSEVYDQIIFAVTQYLQLQNISVGNHAYENKGTKQSAMAICQHFYRQGTICPGNDTFDIDPEVETECFLVEPDEASHLGTPGENKLNLSLDFHRLLTVELQFKLKAINLQTVR-HQELPDCYDFTLTITFDNKAHSGRIKISLDNDISIKECK-DWHVSGSIQKNTHYMMIFDAFVILTCLASLVLCARSVIRGLQLQQEFVNFFLLHYKKEVSASDQMEFINGWYIMIIISDILTIVGSVLKMEIQAK--SLTSYDVCSILLGTSTMLVWLGVIRYLGFFAKYN----------LLILTLQAALPNVMRFCCCAAMIYLGYCFCGWIVLGPYHEKFRSLNRVSECLFSLINGDDMFSTFAKMQQKSYLVWLFSRVYLYSFISLFIYMILSLFIALITDTYETIKHYQQDGFPETELRKFIAECKDLPNSG---KYRLEDDPPGS------LLCCCKK----------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8TDD5-1", "uniprot_id": "MCLN3_HUMAN", "id": "Q8TDD5-1", "name": "Mucolipin-3", "aln": "-----------------------------------------------------------MADP-EVVVSSCSSHEEENRCNFNQQTSPSEELLLEDQMRRKLKFFFMNPCEKFWARGRKPWKLAIQILKIAMVTIQLVLFGLSNQMVVAFKEENTIAFKHLFLKGYMDRM--------DDTYAVYTQSDVYDQLIFAVNQYLQLYNVSVGNHAYENKGTKQSAMAICQHFYKRGNIYPGNDTFDIDPEIETECFFVEPDEPFHIGTPAENKLNLTLDFHRLLTVELQFKLKAINLQTVR-HQELPDCYDFTLTITFDNKAHSGRIKISLDNDISIRECK-DWHVSGSIQKNTHYMMIFDAFVILTCLVSLILCIRSVIRGLQLQQEFVNFFLLHYKKEVSVSDQMEFVNGWYIMIIISDILTIIGSILKMEIQAK--SLTSYDVCSILLGTSTMLVWLGVIRYLGFFAKYN----------LLILTLQAALPNVIRFCCCAAMIYLGYCFCGWIVLGPYHDKFRSLNMVSECLFSLINGDDMFATFAKMQQKSYLVWLFSRIYLYSFISLFIYMILSLFIALITDTYETIKQYQQDGFPETELRTFISECKDLPNSG---KYRLEDDPPVS------LFCCCKK----------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9PLH2-1", "uniprot_id": "A0A8M9PLH2_DANRE", "id": "A0A8M9PLH2-1", "name": "", "aln": "-----------------------------------------------------------MDDSREDYLCINDPNGNWSECEAHVDP-------ALEAFRRKLKYFFMNPCDKYKARQRKPWKLFLQIVKIAVVTVQLVSFGLSNQMVVQFKEENLLTFRHLFLKNYSESN--------TNTYAIYTQLDVYTHITHIVQQFLMLPSITVGNHEYEQEGDVYTPLCICQQFYHNGSISPANETFDIDSRVDQECSLIYPQDPFT-----ESPLNFTLHFERLLSVTVNFTLKAINLETVE-YHELPDCYVFNIMIQFDNKAHSGRILVDLDNEVHIYECS-DWSMTGASARNMYMMVLFDAVVILILSTSLLLCIRSVKAGVLLQKEYSEFSLRRYRKCVSLSERLEFINGWYLLIIVSDVLTISGSVLKIVIQLK--AVASYDLCSILLGTGTMLVWIGVLRYMGYLKKYNSMLCVCCVVQILIITLRVALPNVIRFTCCAAMIYLGYCFCGWIVLGPYHTKFRTLNTVSESLFSLINGDDMFATFKNMQQKSFVVWLFSRLYLYTFVSLFIYMVLSLFITLITDTYDTIKHQQLDGEPVSDLQAFVLQCKDLPDSG---EFSVEKTNSISSTGGGKLMCCCSHRSSDSDEDTHFSECSS------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8M9P7U6-1", "uniprot_id": "A0A8M9P7U6_DANRE", "id": "A0A8M9P7U6-1", "name": "", "aln": "-----------------------------------------------------------MSDR--------ASHTHESATLLDPEC--------VESLRRKLKYFFMSPCQKYSTRGRIPWKMMLQILKIVIITVQLVSFGLSNEMMVTFKEENLIAFKHFFLKNYKDS---------NKHYALYTKHEVHDHILYTIRRYLQLQNLTIGNQALEMIDGLATPLSLCQQLYRHARVVPSNETFEIDPHVETECVSVYPLSPITTDS-LENSLNLTLDFQRLLAVNIYLKIKAINIQTVR-HQELPDCYDFSINIMFDNRAHSGQIKISLSSGVQINVCK-DWNISGSTDSHFALIVVFDCLIICFCLLSLILCTRSVHTGFLLQTEYRRFMSSQHSKSVSWSERLEFINGWYILIIISDALTIAGSILKICIQSK--ELTSYDVCSILLGTATMLVWIGVMRYLSFFQKYY----------ILILTLKAALPNVIRFSICAVMIYLSYCFCGWIVLGPHHENFRTFSRVAGCLFSMINGDEIYSTFTKLREYSTLVWLFSRLYVYSFIPVFTYMVLSVFIALITDTYETIRHYQKHGAPLSELQAFIADCRDPRNYD---KNTTNEDEESS------SFCCLCAPCVFCT----------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VW35-1", "uniprot_id": "Q9VW35_DROME", "id": "Q9VW35-1", "name": "", "aln": "MQSYGPGAQTAPAVKRRTDSYEAAQQQQQSPESDEEYVNTRILRRQVQLQSTPVAPVVPMPISAGSGTAPPSVDGREEQPEFPGSSAAS---YQEERMRRKLQFFFMNPIEKWQAKRKFPYKFVVQIVKIFLVTMQLCLFAHSRYNHINYTGDNRFAFSHLFLRGWDSSREVESYPPAVGPFALYLKSEFFDTVQYAVNGYANVS-RSIGPYDYPTPNNTMPPLKLCLQNYREGTIFGFNESYIFDPHIDEVCERLPPNVTTIGVENYLRQRDVEVNFASLVSAQLTFKIKTVNFKANGGPLSAPDCFRFDISITFNNRDHDGQMLLSLDAEATRLKCHGATDFISDANFDSMLRSVLNIFVLLTCALSFALCTRALWRAYLLRCTTVNFFRSQFGKELSFDGRLEFVNFWYIMIIFNDVLLIIGSALKEQIEGRYLVVDQWDTCSLFLGIGNLLVWFGVLRYLGFFKTYN----------VVILTLKKAAPKILRFLIAALLIYAGFVFCGWLILGPYHMKFRSLATTSECLFALINGDDMFATFATLSSKATWLWWFCQIYLYSFISLYIYVVLSLFIAVIMDAYDTIKAYYKDGFPTTDLKAFVGTRTAEDISSGVFMTDLDDFDQTSFLDVVKSICCCGRCGRHQEPAQPNSGYTSLSSIMK", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * . . : :****::***.* :*: :: : *:*: :**:** ::*:** *. *. : :. :* ::* *:**:.: . :*:* : :.. : . : : : ::* . ..: :* : *:.. : *::: :*..:: * : * . :. :.* *::. : :.:*::*::: . ***: * : * *:*: *.*:: :.*. * . . . ::: .:: *: ** *:: . *: .* :. * :* . ::**:* **::**..* * * ** ** *: : : .:* **::** ..:***:**:**:.:: .* ::*:**: * *:::** .* :** .: ****::***:* :**:: .: .**::****::::** .: . : :* *.::*:*:*:.:: *::**:**::* *:*:**: .* * ::*: *: . :. * :** ", "identical_positions": 136, "similar_positions": 192, "identity": "20.42%" }, { "cls_id": "homologset.agr.MGI:1890504", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D4A930-1", "uniprot_id": "D4A930_RAT", "id": "D4A930-1", "name": "", "aln": "MVLPTCPMAEFALPRHSAVMERLRRRIELCRRHHSTCEARYEAVSPERLELERQHTFALHQRCIQAKAKRAGKHRQPPAAATAPAAAPAPAPAPAAARLDSADGPEHGRP--------VAHLHDPVKRSLDSAASPQNGDQPNGYGDLFPGHKKTRREAPLG--VSVSANGLPPASPLGQPDKPPVGDALQTGGKHSLGLDPINKKCLADSSIHLNGGSNSSEPFPLSLSKELKQEPVDDLPCMIAGAGSSVAQSNLMPDLNLNEQEWKELIEELNRSVPDEDMKDLFTEDFEEKKDPEPPGSATQTPLAQDIN-IKTEFSPAAFEQEQ-----LGSPQVRAGSAGQTFLAPSSAPVGTDSPSLGNSQTLFHTTGQPGVDSSSPNLMPASAQAQNAPRALTSVVLPSQGPGGASELSSAHQLQQIAAKQKREQMLQNPQQTAPAPGPGQLSTWQQAGPSHSPLDAPYPMEKPASPSGYKQDFTNSKLLMMPSVNKSSPRPGGPYLQP-SHSNLLSHQSPSN---LNPNPVNNQGSMLDYGNTKPLSHYKADCGQGGPGSGQNKPALMAYLPQQLPHLSNEQNSLFLMKPKPGNMPFRSLVPPGQEQNPSSVP----VPAPAASVGTQP-SVSVASTHSSS-YLSSQ------QQAAVMKQHQLLLDQQKQREQQ--QLQQQQFLQR-QHLLAE---------QEKQQFQRHLTRPPPQYQDPTQSTFQQQVGQFTGPSAAVPGMNNLGPSNSSCPRVFPQPGTLMSMGPGHAPVSSLPPSSGQQDRGVAQFTGSQSLPHNSLYG-MASGLAQIVAQPPPQATSTHAHIP-----RQTNVGQNASTSAAYGQNSLGSASLSQQHS---KGTLPPGLAKPQVPRVSAAMGSQNPSWQHQGMPNLSSQTPGNSS--VSPFTAASSFHR-QQAHLKMSAQQFSQAMPTRPMAPLSSAAAAGPMLPSVSTQQRNSAP-----APAPPQAASQQGLPGLSPSG----PELGAFGQSPTSQMNSRPGLHCAQAYPVRTMG-QELPFAYSGQPGSSGLSSVAGHTDLIDSLLKNRTSEEWINELDDLLGSQ-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q6T264-1", "uniprot_id": "MAML1_MOUSE", "id": "Q6T264-1", "name": "Mastermind-like protein 1", "aln": "MVLPTCPMAEFALPRHSAVMERLRRRIELCRRHHSTCEARYEAVSPERLELERQHTFALHQRCIQAKAKRAGKHRQPPAAATAPVAAPAPASAPAAARLDAADGPEHGRP--------VAHLHDTVKRSLDSAASPQNGDQPNGYGDLFPGHKKTRREAPLG--VSVSANGLPPASPLGQPDKPSGGDTLQTAGKHSLGLDPINKKCLADSGIHLNGGSNSSEPFPLSLSKELKQEPVDDLPCMIAGAGGSVAQSNLMPDLNLNEQEWKELIEELNRSVPDEDMKDLFTEDFEEKKDPEPPGSATQTPLAQDIN-IKTEFSPAAFEQEQ-----LGSPQVRAGSAGQTFLGASSAPVGTDSPSLGSSQTLFHTTSQPGVDNSSPNLMPASAQAQSAQRALTSVVLPSQGPGGASELSSAHQLQQIAAKQKREQMLQNPQQAAPAPGPGQLATWQQAGPSHSPLDVPYPMEKPASPSGYKQDFTNSKLLMMPGVNKSSPRPGGPYLQP-SHSNLLSHQSPSN---LNQNPVNNQGSVLDYGNTKPLSHYKADCGQGGPGSGQNKPALMAYLPQQLPHLSNEQNSLFLMKPKSGNMPFRSLVPPGQEQNPSSVP----VAAPAASVGTQP-TVSVASTHNSSPYLSSQ------QQAAVMKQHQLLLDQQKQREQQQQQLQQQQFLQR-QHLLAE---------QEKQQFQRHLTRPPPQYQDPTQSTFPQQVGQFTGPSAAVPGMNNLGPSNSSCPRVFPQPGTLMSMGPGHAPVSSLPSSSGQQDRGVAQFTGSQSLPQNSLYG-MASGLAQIVAQPPPQATSTHAHIP-----RQTNVGQNASTSAAYGQNSLGSASLSQQHS---KGTLPPGLTKPQVPRVSAAMGSQNASWQHQGMPNLSSQTSGNSS--VNPFTAAPSFHI-QQAHLKLAGQQFSQAMPSRPMAPLSSAGAAGPMLPPVSAQQRNSAP-----ASAPPQAAPQQGLPGLSPSG----PELGAFGQSPTSQMSGRPGLHCAQAYPVRTMG-QELPFAYSGQPGSSGLSSVAGHTDLIDSLLKNRTSEEWINELDDLLGSQ-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q92585-1", "uniprot_id": "MAML1_HUMAN", "id": "Q92585-1", "name": "Mastermind-like protein 1", "aln": "MVLPTCPMAEFALPRHSAVMERLRRRIELCRRHHSTCEARYEAVSPERLELERQHTFALHQRCIQAKAKRAGKHRQPPAAT-------APAPAAPAPRLDAADGPEHGRP--------ATHLHDTVKRNLDSATSPQNGDQQNGYGDLFPGHKKTRREAPLG--VAISSNGLPPASPLGQSDKPSGADALQSSGKHSLGLDSLNKKRLADSSLHLNGGSNPSESFPLSLNKELKQEPVEDLPCMITGTVGSISQSNLMPDLNLNEQEWKELIEELNRSVPDEDMKDLFNEDFEEKKDPESSGSATQTPLAQDIN-IKTEFSPAAFEQEQ-----LGSPQVRAGSAGQTFLGPSSAPVSTDSPSLGGSQTLFHTSGQPRADNPSPNLMPASAQAQNAQRALAGVVLPSQGPGGASELSSAHQLQQIAAKQKREQMLQNPQQATPAPAPGQMSTWQQTGPSHSSLDVPYPMEKPASPSSYKQDFTNSKLLMMPSVNKSSPRPGGPYLQP-SHVNLLSHQPPSN---LNQNSANNQGSVLDYGNTKPLSHYKADCGQGSPGSGQSKPALMAYLPQQLSHISHEQNSLFLMKPKPGNMPFRSLVPPGQEQNPSSVP----VQAQATSVGTQPPAVSVASSHNSSPYLSSQ------QQAAVMKQHQLLLDQQKQREQQQKHLQQQQFLQRQQHLLAE---------QEKQQFQRHLTRPPPQYQDPTQGSFPQQVGQFTGSSAAVPGMNTLGPSNSSCPRVFPQAGNLMPMGPGHASVSSLPTNSGQQDRGVAQFPGSQNMPQSSLYG-MASGITQIVAQPPPQATNGHAHIP-----RQTNVGQNTSVSAAYGQNSLGSSGLSQQHN---KGTLNPGLTKPPVPRVSPAMGGQNSSWQHQGMPNLSGQTPGNSN--VSPFTAASSFHMQQQAHLKMSSPQFSQAVPNRPMAPMSSAAAVGSLLPPVSAQQRTSAP-----APAPPPTAPQQGLPGLSPAG----PELGAFSQSPASQMGGRAGLHCTQAYPVRTAG-QELPFAYSGQPGGSGLSSVAGHTDLIDSLLKNRTSEEWMSDLDDLLGSQ-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A0R4IKI2-1", "uniprot_id": "A0A0R4IKI2_DANRE", "id": "A0A0R4IKI2-1", "name": "", "aln": "------MMADFVVPRHSAVMERLRRRIELFRRHHTGCENRYDNTAMERLEMERQQTIALQQRFLQTKAKRSNKHRQPPAAAAASADPVGQRGASGGGGSAEIADGGSGTPGEQSRNSTLIALQETVKRKLESAESPLGRDQVNGFTDGYPPNKKSCVEDAMGGLNGVSNGVVPPLSPLDTKHNVN-TDAMMANGNHRVVGSEHNGASLKDNGAVRGSESDFR-------LKEPKQEPVDDALSCILPQGGANGNNSLFPDLNLNDQDWSEIMEEFNRSVPYEDIQELFSVSFGDRKDPELTSAAAQSLISQDLPNVKTEISPATATSAFEQDSCNGSPQMRPTSSGPPLHTNSPVTAPATSPALPVPQHSQQGSIQSRALPN--HLMPVPPKDLSPAQQLQQLAQQR----------AILHSQQHVVQKPPQQKPPQQQPTKFHQQPSHSTSWPQNAPTQSQMGGTFGLEKPTSPSLYPQDFPNPKTLLMPNKGSPKAGAPAGYMQPGGHANMLSHPAAPTGPLGHPSNPGAQAAMLDFNNTKPLSHYDD-----GPPGAPRGPPTTQNHNKPNQAILNMMRQQQIQKQRAPTMNFRPAHLPHTAQDSGSYPPNTHVPGPSNTMTPQTSSNSIPGHHNNPAYLKQQQIQLMNQQKQFQLQRQIMVEQEKQRQQQEQQLQRHLTRPPPQYQDQQNPQAQQNPFQQQQQQVSQFTSVPPCLAQQHTSNFSEHT--ISGASQPIGNVNTLSGPAPGTQRMFSQTQGMMGIGVGQNAGPNTGPSTAASQADMSLPPCSNLDVQQVLYGNISMHASHANQQRQPVSTMSAAYRQNVLAAQQQAHLKNQPNAALLKQQQQQLARLPNNMANAMSNNMGSAMPTSMPTSIPGALPVQAQSWQQQPPQQHPALQSGSANGAMPAGFPNSSFHMQSRLTKLPNNTPFPQGGMGNSAAGRTMGGMNPGQMMTNMNQQRTNNPGMPQQLPPPVQQTAQQGQPQAPPQTQQVLPDLGPFSQAQAVPN-RTTGLQCNQAYQLNRAANQQLQFSYNTQSGGS-LSGFPAETDLVDSLLKDQSTQQWMDDIDELLASHQ", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " **:*.:**************** ****: ** **: .: ****:***:*:**:** :*:****:.********: . *. . . * * *::.***.*:** ** . ** **: * :* :**: * .:* .:* . :** ***. .: *:: : *:* : . * * *.. .. *: ** *****:* . * .: .:..*:******:*:*.*::**:***** **:::**. .* ::**** ..:*:*: ::**: :***:***: . ****:*. *:* .: *.... : **:* .* : : *. . :***...: .. : * :. : : ** ..:: :* : * : *.: ::* * .*::* :. .: :***:*** * ***.*.* *:**. ..... . . *:** .* *:*** .... : . . *.::**:.********. .* .. *. : : : .. : * :. .* **. * *:..* * * . : :: .*. : *:.. *... **..* ** . *:*::::*:***:** :**:: *: : *::** ::* ** : ..* ::. ::*.* .: .:*.*. . .. *:*.*. :* :* *: . .. ..:. .: .:: . *: :. *** :: :: * * :* *: :* :* . :* *:. : *.:: ...: ..:... . :. *: * ***:* : .. .*.:. : . . .*** .: *.*. .. * : .. : . ***.. * ..* :.*** * .* *:**.*.*: : .**:* *** :. . *:* *:*. *.*.* **.....***:*****::::::*:.::*:**.*: ", "identical_positions": 308, "similar_positions": 342, "identity": "28.41%" }, { "cls_id": "homologset.agr.MGI:1890505", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P43884-1", "uniprot_id": "PLIN1_RAT", "id": "P43884-1", "name": "Perilipin-1", "aln": "-------------------MSMNKGPTLLDGDLPEQENVLQRVLQLPVVSGTCECFQKTYNSTKEAHPLVASVCNAYEKGVQGASNLAAWSMEPVVRRLSTQFTAANELACRGLDHLEEKIPALQYPPEKIASELKGTISTRLRSARNSISVPIASTSDKVLGATLAGCELALGMAKETAEYAANTRVGRLASGGADLALGSIEKVVEYLLP--PDKVESAPSSGRQKTQKAPKAKPS-LLRRVSTLANTLSR----HTMQTTARALKRGHSLAMWIPGVAPLSSLAQWGASAAMQVVSRRQSEVRVPWLHNLAASKDENHEDQTDTEGEETDEEEEEEESEAEENVLREVTALPTPLGFLGGVVHTVQKTLQNTISAVTWAPAAVLGTVGRILHLTPAQAVSSTKGRAMSLSDALKGVTDNVVDTVVHYVPLPRLSLMEPESEFQDIDNPPAEVERK-----GSGSRPASPESTARPGQPR-AACAVRGLSAPSCPDLDDKTET--SARPGLLAMPREKPARRVSDSFFRPSVMEPILGRTQYSQLRKKS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8CGN5-1", "uniprot_id": "PLIN1_MOUSE", "id": "Q8CGN5-1", "name": "Perilipin-1", "aln": "-------------------MSMNKGPTLLDGDLPEQENVLQRVLQLPVVSGTCECFQKTYNSTKEAHPLVASVCNAYEKGVQGASNLAAWSMEPVVRRLSTQFTAANELACRGLDHLEEKIPALQYPPEKIASELKGTISTRLRSARNSISVPIASTSDKVLGATLAGCELALGMAKETAEYAANTRVGRLASGGADLALGSIEKVVEFLLP--PDK-ESAPSSGRQRTQKAPKAKPS-LVRRVSTLANTLSR----HTMQTTAWALKQGHSLAMWIPGVAPLSSLAQWGASAAMQVVSRRQSEVRVPWLHNLAASQDESHDDQTDTEGEETDDEEEEEESEAEENVLREVTALPNPRGLLGGVVHTVQNTLRNTISAVTWAPAAVLGTVGRILHLTPAQAVSSTKGRAMSLSDALKGVTDNVVDTVVHYVPLPRLSLMEPESEFRDIDNPSAEAERK-----GSGARPASPESTPRPGQPRGSLRSVRGLSAPSCPGLDDKTEA--SARPGFLAMPREKPARRVSDSFFRPSVMEPILGRAQYSQLRKKS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O60240-1", "uniprot_id": "PLIN1_HUMAN", "id": "O60240-1", "name": "Perilipin-1", "aln": "-------------------MAVNKGLTLLDGDLPEQENVLQRVLQLPVVSGTCECFQKTYTSTKEAHPLVASVCNAYEKGVQSASSLAAWSMEPVVRRLSTQFTAANELACRGLDHLEEKIPALQYPPEKIASELKDTISTRLRSARNSISVPIASTSDKVLGAALAGCELAWGVARDTAEFAANTRAGRLASGGADLALGSIEKVVEYLLP--PDKEESAPAPGHQQAQKSPKAKPS-LLSRVGALTNTLSR----YTVQTMARALEQGHTVAMWIPGVVPLSSLAQWGASVAMQAVSRRRSEVRVPWLHSLAAAQEEDHEDQTDTEGEDT---EEEEELETEENKFSEVAALPGPRGLLGGVAHTLQKTLQTTISAVTWAPAAVLGMAGRVLHLTPAPAVSSTKGRAMSLSDALKGVTDNVVDTVVHYVPLPRLSLMEPESEFRDIDNPPAEVERREAERRASGAPSAGPEPAPRLAQPRRSLRSAQSPGAPPGPGLEDEVATPAAPRPGFPAVPREKPKRRVSDSFFRPSVMEPILGRTHYSQLRKKS", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9PFT8-1", "uniprot_id": "A0A8M9PFT8_DANRE", "id": "A0A8M9PFT8-1", "name": "", "aln": "-------------------MASEKK---DTGEVLKDQNVFFRILNIRSVNAALESIEKTYTSTKQSHPIISSVCGLYEKGVSRAGNLAVWSMKPALHVLQPQLVAANSMACKGLDRLEEKVPALQSPPAELAANIKGLMSSTLEAAKDGITCPIKHSSNVVLDKVSSRYQQSKNTLSGGIQYILNSKLVFLAEQRASRALSLTENLIDCILPGTSDKTENDRSTEEQQESYVGASDPMPIFSRLGALASTICRRAFEKTFAQLQLSTHQGHTLVKRIPGLNPLVEFTMS----TMRTMGGIIKGFPSSMATYLKDGQQHSPLKEMAN----------DEHGQVKSNGLVSGLGQR-LLKVYGSVVANIKKTSRTSFNLAKDGVNIVLGSFG--------------------------TVREKTLHKLSYYGLIPRR-LSKTEGGSQPAEKDGAEECLCG--------FLVLESNVGNIIHSRNDNSEKQPLKVTEPMDISEETRQ---LKKKLMKQIPMQHRVVLGGSNKKSPTTEPVGRRV---------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VXY7-1", "uniprot_id": "LSD2_DROME", "id": "Q9VXY7-1", "name": "Lipid storage droplets surface-binding protein 2", "aln": "MASAEQKHATGNGTTGNGTAMNDVDQPKDAKDLLPHLESLERIIKLPVVNAAWDKSQDVYGKVKGKNRVFEWALTAAEDCVTRA----VTTAAPFVTKLDRPIAYVDQTLVKGIDKLEVKAPIIKDTPQEIYNQAKSKVIDVVQPHLERVVKFKAAGQQKAASLKDLAWQKAN--------EVLATQYGSLAVNGVDTTTALAERLLEYYFP----KCESDVEEDNDDKQNAVVQNGK---SSENDMP-----------------------------------------------------VPASEDPVLHTVQTVGR---------------------------------LSNKISRRVYRNVSRQIKQVQKGNINDYLSSLIAAL-----------------------------------KLHQYINFINSSMGTNVEQSGG-----------------------------SSSDACSPFGTTTSTTTTTTTSSTSNNKPVVA-------LPHVAKSKRAPAVSSQ-----------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : :: . : : *:::: *..: : :..* ..* : :. . *. * * . : * : *. :. .:. :*:*:** * * :: .* :: : *. : :.. : : .: . . : : :: ** .. : . *.::: :* * *. .: . . . :. . : . . .* :::. : .:. . .* :. : . : .. . .. . .. . : : :... ", "identical_positions": 25, "similar_positions": 109, "identity": "4.54%" }, { "cls_id": "homologset.agr.MGI:1890508", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D4A5K6-1", "uniprot_id": "D4A5K6_RAT", "id": "D4A5K6-1", "name": "CAAX prenyl protease", "aln": "MGMWASVDAMWDFPAEKRIFGAVLLFSWTVYLWETFLAQRQRRIYKTTTHVPPELEQIMDSDTFEKSRLYQLDKSTFSFWSGLYSEVEG-TFILLFGGIPYLWRLSGRFCSSAG---FGPEYEIIQSLVFLLLATLFSALTGLPWSLYNTFVIEEKHGFNHQTLEFFMKDAIKKFIVTQCILLPVSSLLLYIIKIGGDYFFIYAWLFTLVVSLVLVTIYADYIAPLFDKFTPLPEGKLKQEIEVMAKSIDFPLTKVYVVEGSKRSSHSNAYFYGF-FKNKRIVLFDTLLEEYSVPNKDNQEEPGLEPRNEGEGDSEEVKSKVKNKKQGCKNEEVLAVLGHELGHWKLGHTVKNIIISQMNSFLCFFLFAVLIGRRELFAAFGFYDSQPT-------------LIGLLIIFQFIFSPYNEVLSFCLTVLSRRFEFQADAFAKKLGKAKDLYSALIKLNKDNLGFPVSDWLFSTWHYSHPPLLERLQALKNAKRD---", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q80W54-1", "uniprot_id": "FACE1_MOUSE", "id": "Q80W54-1", "name": "CAAX prenyl protease 1 homolog", "aln": "MGMWASVDAMWDFPAEKRIFGAVLLFSWTVYLWETFLAQRQRRIYKTTTRVPAELEQIMDSDTFEKSRLYQLDKSTFSFWSGLYSEVEG-TFILLFGGIPYLWRLSGQFCSSAG---FGPEYEIIQSLVFLLLATLFSALTGLPWSLYNTFVIEEKHGFNHQTLEFFMKDAIKKFIVTQCILLPVSALLLYIIKIGGDYFFIYAWLFTLVVSLVLVTIYADYIAPLFDKFTPLPEGKLKQEIEVMAKSIDFPLTKVYVVEGSKRSSHSNAYFYGF-FKNKRIVLFDTLLEEYSVPNKDNQEESGMEARNEGEGDSEEVKAKVKNKKQGCKNEEVLAVLGHELGHWKLGHTVKNIIISQMNSFLCFFLFAVLIGRRELFAAFGFYDSQPT-------------LIGLLIIFQFIFSPYNEVLSFCLTVLSRRFEFQADAFAKKLGKAKDLYSALIKLNKDNLGFPVSDWLFSTWHYSHPPLLERLQALKNAKQD---", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O75844-1", "uniprot_id": "FACE1_HUMAN", "id": "O75844-1", "name": "CAAX prenyl protease 1 homolog", "aln": "MGMWASLDALWEMPAEKRIFGAVLLFSWTVYLWETFLAQRQRRIYKTTTHVPPELGQIMDSETFEKSRLYQLDKSTFSFWSGLYSETEG-TLILLFGGIPYLWRLSGRFCGYAG---FGPEYEITQSLVFLLLATLFSALTGLPWSLYNTFVIEEKHGFNQQTLGFFMKDAIKKFVVTQCILLPVSSLLLYIIKIGGDYFFIYAWLFTLVVSLVLVTIYADYIAPLFDKFTPLPEGKLKEEIEVMAKSIDFPLTKVYVVEGSKRSSHSNAYFYGF-FKNKRIVLFDTLLEEYSVLNKDIQEDSGMEPRNEEEGNSEEIKAKVKNKKQGCKNEEVLAVLGHELGHWKLGHTVKNIIISQMNSFLCFFLFAVLIGRKELFAAFGFYDSQPT-------------LIGLLIIFQFIFSPYNEVLSFCLTVLSRRFEFQADAFAKKLGKAKDLYSALIKLNKDNLGFPVSDWLFSMWHYSHPPLLERLQALKTMKQH---", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P47154-1", "uniprot_id": "STE24_YEAST", "id": "P47154-1", "name": "CAAX prenyl protease 1", "aln": "MFDLKTILDHPNIPWKLIISG----FSIAQFSFESYLTYRQYQKLS-ETKLPPVLEDEIDDETFHKSRNYSRAKAKFSIFGDVYNLAQK-LVFIKYDLFPKIWHMAVSLLNAVLPVRFHMVSTVAQSLCFLGLLSSLSTLVDLPLSYYSHFVLEEKFGFNKLTVQLWITDMIKSLTLAYAIGGPILYLFLKIFDKFPTDFLWYIMVFLFVVQILAMTIIPVFIMPMFNKFTPLEDGELKKSIESLADRVGFPLDKIFVIDGSKRSSHSNAYFTGLPFTSKRIVLFDTLVNSNST-------------------------------------DEITAVLAHEIGHWQKNHIVNMVIFSQLHTFLIFSLFTSIYRNTSFYNTFGFFLEKSTGSFVDPVITKEFPIIIGFMLFNDLLTPLECAMQFVMSLISRTHEYQADAYAKKLGYKQNLCRALIDLQIKNLSTMNVDPLYSSYHYSHPTLAERLTALDYVSEKKKN", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "A1ZAM7-1", "uniprot_id": "A1ZAM7_DROME", "id": "A1ZAM7-1", "name": "CAAX prenyl protease", "aln": "-------MSAHFWDDPLAILYIIIAFLVLDNLWGVYLMLRDIQVAYKTQQVPNVISPYLPQELYDKMRVYKIHKGWFTIVNTLLSAVILGIMELYFGFYAWLYGVAGKCALSKW-----MEHEACVSVIFVLLLSVYFWLKSVPAMIYESCCIKSLQPRPKPPWWSRICHFVVDLVVGAMITTLVVVALVYMFIGLGPYAPLGLYLQSLILTMIVLLLIPFMIHPFVGQSVPLENSNLRTQLEYLTRQVGFPMSQVRIIRVHDPNTGSNAFFYGC-CCLKRIVIFDTLLLNRGKSDLSHLTAEELG--------------------RGLADPQVVAVVAHELGHWRNGHFYKAIMAFQVHLILTILLFAFLFSHGPIYQAVGFPPGLQP------------TVIGCLIIFGFVLTPYMTLANFSMLSMTRCFEYQADRFAYQLGYGGELRQALLKLYADNLAFPVSDPCYSSWNHTHPTMLDRLSRLEEFRR----", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * * : :* *: : ::* : : .: :.* * *. *. *:: . : . . . : :. . :: :: *: *: * : * .:* *. ::. : . : . : .: : * : :: :: : ::: :: : : . * *:..: .** :.:*: .:* :: :.**: :: :: . .: ***:* * ****:****: . . :: **:.**:***: .* : :: *:: :* : **: : . :: :.** . :* :::* :::* .* : ::* .*:*** :* :** :* **:.* .**. * :* ::::**.: :** *. . ", "identical_positions": 77, "similar_positions": 140, "identity": "15.52%" }, { "cls_id": "homologset.agr.MGI:1890510", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8J8XD13-1", "uniprot_id": "A0A8J8XD13_RAT", "id": "A0A8J8XD13-1", "name": "V-type proton ATPase 21 kDa proteolipid subunit c''", "aln": "-MTG--------LELLYLGIFVAFWACMIVVGICYT--IFDLGFRFDVAWFLTETSPFMWSNLGIGLAISLSVVGAAWGIYITGSSIIGGGVKAPRIKTKNLVSIIFCEAVAIYGIIMAIVISNMAEPFS---ATDPKAIGHRNYHAGYSMFGAGLTVGLSNLFCGVCVGIVGSGAALADAQNPSLFVKILIVEIFGSAIGLFGVIVAILQTSRVKMGD--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q91V37-1", "uniprot_id": "VATO_MOUSE", "id": "Q91V37-1", "name": "V-type proton ATPase 21 kDa proteolipid subunit c''", "aln": "-MTG--------LELLYLGIFVAFWACMVVVGICYT--IFDLGFRFDVAWFLTETSPFMWSNLGIGLAISLSVVGAAWGIYITGSSIIGGGVKAPRIKTKNLVSIIFCEAVAIYGIIMAIVISNMAEPFS---ATEPKAIGHRNYHAGYSMFGAGLTVGLSNLFCGVCVGIVGSGAALADAQNPSLFVKILIVEIFGSAIGLFGVIVAILQTSRVKMGD--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q99437-1", "uniprot_id": "VATO_HUMAN", "id": "Q99437-1", "name": "V-type proton ATPase 21 kDa proteolipid subunit c''", "aln": "-MTG--------LALLYSGVFVAFWACALAVGVCYT--IFDLGFRFDVAWFLTETSPFMWSNLGIGLAISLSVVGAAWGIYITGSSIIGGGVKAPRIKTKNLVSIIFCEAVAIYGIIMAIVISNMAEPFS---ATDPKAIGHRNYHAGYSMFGAGLTVGLSNLFCGVCVGIVGSGAALADAQNPSLFVKILIVEIFGSAIGLFGVIVAILQTSRVKMGD--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F1QYM3-1", "uniprot_id": "F1QYM3_DANRE", "id": "F1QYM3-1", "name": "V-type proton ATPase 21 kDa proteolipid subunit c''", "aln": "MMNG--------HAILYTGVTLAFWSTMVIVGICYT--IFDLGFRFDVAWFLTETSPFMWANLGIGLAISLSVVGAAWGIYITGSSIIGGGVKAPRIKTKNLVSIIFCEAVAIYGIIMAIVISNLAENFS---GTTPETIGSKNYQAGYSMFGAGLTVGFSNLFCGICVGIVGSGAALADAQNANLFVRILIVEIFGSAIGLFGVIVAILQTSKVKMGN--", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VFE3-1", "uniprot_id": "Q9VFE3_DROME", "id": "Q9VFE3-1", "name": "V-type proton ATPase 16 kDa proteolipid subunit c", "aln": "-MAAQI------RTVVSQTFLWLFLAVATILTLYFV--MTGKGERVSVGWFLASSNPYMWACLGIGLSVSLSVVGAALGIHTTGTSIVGGGVKAPRIKTKNLISVIFCEAVAIYGLITAIVLSGQLEQFSMETALSQAAIQNTNWFSGYLIFGAGLAVGLVNLFCGIAVGIVGSGAALSDAANAALFVKILIVEIFGSAIGLFGLIVGIYMTSKSKMGDKE", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VFE5-1", "uniprot_id": "Q9VFE5_DROME", "id": "Q9VFE5-1", "name": "V-type proton ATPase 16 kDa proteolipid subunit c", "aln": "-MISKM------SFGLFFMLFVLGAASLGAVGIIFANVMVNMGERMGLGWFLYTSNPFLWSGMGIFLACALSVLGAASGIYMIGCSVAGGGVRSPRIKTKNLISVIFCEAVAIYGLITAILLSGNVNKFSSVRLITDSTVMATNMFTGFATFGAGLCVGMVNVACGIAVGIVGSGAALADAANSALFVKILIVEIFGSAIGLFGLIVAIYMTSKAETIN--", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P23968-1", "uniprot_id": "VATO_YEAST", "id": "P23968-1", "name": "V-type proton ATPase subunit c''", "aln": "-MNKESKDDDMSLGKFSFSHFLYYLVLIVVIVYGLYKLFTGHGSDINFGKFLLRTSPYMWANLGIALCVGLSVVGAAWGIFITGSSMIGAGVRAPRITTKNLISIIFCEVVAIYGLIIAIVFSSKLTVAT-----AENMYSKSNLYTGYSLFWAGITVGASNLICGIAVGITGATAAISDAADSALFVKILVIEIFGSILGLLGLIVGLLMAGKASEFQ--", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * . : : . * .... ** :.*::*: :** *. .***:*** **. * *: *.**::***.****:*:****.*****:* **::*. : * :*: * **: ** *: **:.***.*: **::** :. ***:**::***** :**:*:**.: :.: . : ", "identical_positions": 76, "similar_positions": 56, "identity": "34.39%" }, { "cls_id": "homologset.agr.MGI:1890518", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8M9PLT8-1", "uniprot_id": "A0A8M9PLT8_DANRE", "id": "A0A8M9PLT8-1", "name": "", "aln": "----------------------------------MGSMNHPKHFKSGETQNDLGSAHQKRSD----------------------------------PEPSCVSMKSDWSMNHPIKFKSGDTKNDLSSVQK-RSD-PEPSCVSMKSDWSMDPPMQFKSKDTPPDLSSVHQERSEP-EPSCMSMNS-DLPLDPPIRYKSG-----------------------------------ETQNDLSPQVFNTFRSNLLKKFECLYEGTAAQGNPTLLNEIYTELYITESKSGEISHEHEVRQIETQSRRSTTEDTAIKCRDIFTPLPGQDKAIRTVLTKGVAGIGKTVSVQKFILDWAEEKENQD-VQLIFPLPFREINLMKDKTLSLSDLLQLFFPQTKEMEISSDKYKVLFIFDGLDECRLSLDFQSAVRLCDVSESASVDELLTNLIVGNLLPSALIWITSRPAAADLVPSECVHR-VTEVRGFNDPQKEEYFSKRISDQSLANTIISHLKSSRSLYIMCHIPVFCWISATVLEKMLSEAET-AEIPKTLTQMYTHFLILQTNIKHQKDYEEKLTDEDMILKLGKVAFQQLMKGNIIFYEEDLRECGIDVAEASVYSGLCTQIFREEFGLYQGKVFSFVHLSIQEHLAALYVHLSCINKSINQFNFAAKQ-SLWSKT--KFMFKT---VALSELHQRAVVETLQSKNGHLDLFLRFLLGLSVESHQILLQRPLK-LKRRSIKNNKTVEYIKKKIRTIDSPEKSIN---LFHCLNELGDHSLVEEIQQYLKSGGINEAKLSSSQWSAVAFVLLTSEKKLEEFNINEFVAENNKTEKLV-------IFKKLLPVIRECRSVQLYNCGLTGEGCAALASALISNPEHLTDLNLSRNNLGDSVTL-LSAVLEDPHCKLEKLWLSYCGVT---------------------------------------------------------DEGCAALVSALRSNPEHLRELNLSGNNLGD-SVTLLSAVLEDPHCKLEKLRLYYCGLTDEGCAALASALRSNPEHLRDLDLSWNKLGDS-VTLLSAVLEDPRCKLEKLELYNCGLTDEGCAALASALRSNPEHLRDLNLSGNKLGDS-VTLLSAVLEDPRCKLEKLWLSDCGLTDEGCAALASALRSNPE-HLTELDLSWNNLSKSTVRLFSDLKDNPHNKLKTLHI-------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8M9PCI8-1", "uniprot_id": "A0A8M9PCI8_DANRE", "id": "A0A8M9PCI8-1", "name": "", "aln": "MEDTQTTIEKDYSPRFSLVHQKRSEPSCVS-IRRDQSVAHPIDFKSEDTQTHLSSVHQERLD----------------------------------PEPSCVSIRSDRSVAHPIDFKSKNTH--LSSVHQERSE-PEPSCVSIRSDRSVAHPIDFKSEDTQTHLSTFHQKRKEA-DPSCVSMRS-DTFMNQPINIKIG-----------------------------------ETQNDLKQNLLNTFRSNLLKKFECLYEGTAVQGNPTLLNEIYTELYITESESGEISHEHEVRQIETQSRRSTTEDTAIKCRDIFTPLPGQNKAIRTVLTKGVAGIGKTVSVQKFILDWAEEKENQD-VQLIFPLPFREINLMKDKTLSLSDLLQLFFPQTKEMEISSEKYKVLFIFDGLDECRLSLDFQSAVRLCDVSESASVDVLLTNLIVGNLLPSALIWITSRPAAADLVPSECVHR-VTEVRGFNDPQKEEYFSKRISDQSLANTIISHLKSSRSLYIMCHIPVFCWISATVLEKMLSEAET-AEIPKTLTQMYTHFLILQTNIKHQKDYEEKLTDEDMILKLGKVAFQQLMKGNIIFYEEDLRECGIDVAEASVYSGLCTQIFREEFGLYQGKVFSFVHLSIQEHLAALYVHLSCLNNNRNEFEQISKQ-SLWSKVRDHFHFNSSKLVSISKLHQRAVNEALQSKNGHLDLFLRFLLGLSVESHQILLQGLMK-LKIRSIQNNETVEYIKKKIRKINFPEKFIN---LFHCLNELGDHSLVEEIQQFLKSGGMNEAKLSSSQWSAVVFVLLTSEKKLEKFDINEFAARNNNTEQLF-------IFKKLQPVIRQCRSVQLSYCGLTDEGCAALASALRSNPEHLRDLYLSGNKLGDSVSL-LSGVLEDPHCKLETLWLSDCGLTSKDSAALASALRSNPEHLRVLDLSWNRLGDSVTLLSAVLEDPHCKLETLLLRDCGLTDEGCAALASALRSNPEHLKHLDLSWSNLGD-SVTLLSAVLEDPRCKLEKLGLSNCGLAEEGCAALASALRSNPEHLRGLNLSVNNLGDS-VTLLSAVLEDPRCKLEKIKLSYCGLTDEGCAALASALRSNPEHLRDLDLSTNNLGDS-VTLLSAILEDPHCKLEKLELKNCGLTDEGCAVLASALRSNPE-HLRDLNLSWNNLSNSTKKLLSDLKDDPHNKLETLHTSLSV---------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0AB32TA29-1", "uniprot_id": "A0AB32TA29_DANRE", "id": "A0AB32TA29-1", "name": "", "aln": "-------------------------------------MEDTKISKDEDYSPRFSSVHQERSD----------------------------------LEPSCVSMRSEQSMGSPMHFRSEDTEADLSSVYQKRSD-PEPSCVSMRSDWSMDLPYNFRSEDTPTDLSSFHHKRTEA-EFSRVSMRS-DMFINHPINIKNV-----------------------------------EAQCNIRQNLLNTFRSNLLKKFECLYEGTAAQGNPTLLNEIYTELYITESESGEISHEHEVRQIETQSRRSTTEDTAIKCRDIFTPLPGQDKAIRTVLTKGVAGIGKTVSVQKFILDWAEEKENQD-VQLIFPLPFREINLMKDKTLSLSDLLQLFFPQTKEMEISSDKYKVLFIFDGLDECRLSLDFESAVRLCDISESASVDVLLTNLIVGNLLPSALIWITSRPAAADLVPSECVHR-VTEVRGFNDPQKEEYFSKRISDQSLANTIISHLKSSRSLYIMCHIPMFCWISATVLEKMLSEAET-AEIPKTLTQMYTHFLILQTNIKHQKDYEEKLTDEDMILKLGKVAFQQLMKGNIIFYEEDLRECGIDVAEASVYSGLCTQIFREEFGLYQGKVFSFVHLSIQEHLAALYVHLSCINNNRDEFEQIKKQ-SLWFKVKDLFQLNSLECVSLFSLHQRAVNEALQSKNGHLDLFLRFLLGLSVESHQILLQRLMK-LKSRSMQTNKTVKYIKMKIWTIDSPEKSIN---LFHCLNELGDHSLVKEIQQYLKSGRINRAKLSSSQWSAVAFVLLTSEKKLEEFNINEFVAGNNENKKQK-------VFQKLLPVIKQSRSVLLYNCGLTEMDWDNLTSALRSNPSDLRVLNLSRNILGNSVTL-LSAVLEDPCSKLEKLWLSDCGLTDEGCAALATALRSNPEHLRELNLSWNNLRDSVTLLSAVLEDPRCKLETLWLSKCGITGKSCAVLASALRSNPEHLRDLDLSGNKLGD-SVTLLSAVLEDPHCKLKILWLSDCGLTDEGCAALASALRSNPGQLRVLDLSENKLKNSGVMQLCAVLEDPHCKLDKLGLYDCSLTDEGCVALASALRSNPEHLRELDLSVNKLRDSGIKLLSAVLEDPRCKLEKLWLSNCGLTDEACAALASALRSNPE-HLRELNLSKNKLGESDVKLLSDLKDDTHYKLKELNY-------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8M3AQ59-1", "uniprot_id": "A0A8M3AQ59_DANRE", "id": "A0A8M3AQ59-1", "name": "", "aln": "---------------------------------------MLKIFQN--------LTAESGKG----------------------------------IRDYVVQIRFCFIMDDTQISRDENVSPGCSSVHQKRSD-PEPSCVSMRSDWSMDPPISFKSKDTPPDFSSVHQKSTES-EPSCVSMRSDDESVDQPLHVRSG-----------------------------------DTETDLSHEALNTFRSDLLKKFECLYEGTAAQGNPTLLNEIYTELYITESESGEISHEHEVRQIETQSRRSTTEDTAIKCRDIFTPLPGQDKAIRTVLTKGVAGIGKTVSVQKFILDWAEEKENQD-VQLIIPLPFREINLMKDKTLSLSDLLQLFFPQTKEMEISSDKYKVLFIFDGLDECRLSLDFQSAVRLCDVSESASVDVLLMNLIVGNLLPSALIWITSRPAAADLVPSECVHR-VTEVRGFNDPQKEEYFSKRISDQSLANTIISHLKSSRSLYIMCHIPVFCWISATVLEKMLSEAET-AEIPKTLTQMYTHLLILQTNIKHQKDYEEKLTDEDMILKLGKVAFQQLMKGNIIFYEEDLRECGIDVAEASVYSGLCTQIFREEFGLYQGKVFSFVHLSIQEHLAALYVHLSCINNNRDGFEEIKKP-SLWSKVKDLLYLNSSQLVSLSELHQRAVNEALQSKNGHLDLFLRFLLGLSVESHQIILQRLMI-LKSRSIQINKTVEYIKMKIRTIDSPEKFIN---LFHCLNELGDHSLVEEIQQYLKSGRINRAKLSESQWSAVAFVLLTSEKKLEEFHINEFVG---ETEKIF-------IFMKLLPVIRECRSVQLN---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------NCGLTDEGCAALASALRSNPEHLRELNLSGNRLGDS-VTLLSALLEDPRCNLEILWLSYCGLTDEGCAALASALRLNPE-HLRELNLSHNNISKSTVKLLSDLKHNPHNKLETLYI-------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8M6YSM0-1", "uniprot_id": "A0A8M6YSM0_DANRE", "id": "A0A8M6YSM0-1", "name": "", "aln": "--MSHKQTLKYFSPVCSSVQQERSDSAEPSSVSVKSHWSIDPPPQMTERRDSLSLALQERSDSPEPSHVSMKSDWSIDPPPQMKEENRSLVQQERSPKSSCVSMKRDWSIDPPPQMNDEDGQKRLSLVQQERSDSAEPSLVSMKSDWSIDPPPQMKDGDRQKSLSLVQQERSDSPEPSHVTMKS-NWSIDPPPQMTDRRDSLRQIPRPRPGAEEPISKKMKYDESVIKSQECMENPSLIFSHEVNTFRVNLLKKFQCLYEGMVTQDNPALLNEIYTELYITESESGEISNEHEVRQIETQSRRSTTEDTAIKCRDIFTPLPGQDKAIRTVLTKGVAGIGKTVSVQKFILDWAEEKENQD-VQLIFPLPFREINLMKDKTLSLSDLLQLFFPETKEIDIFSDKYKILFIFDGLDECRLLLNFKSNEILQHVTKTSSVDVLLTNLIVGNLLPSALIWITSRPAAADLVPSECVHR-VTEVRGFNDPQKEEYFSKRISDQSLANTIISHLKSSRSLYIMCHIPVFCWISATVLEKMLSEAET-AEIPKTLTQMYTHFLMAQINTKDMKYTGKK--DKDMIFKLGKLAYEQLERGNVIFYEEDLRECGIDVAEASVYSGLCTQIFREEFGLYQGKVFSFIHLSVQEHLAALYVHLLFTNHNRNVFEQMTKKTSKTLDILDCFHSNSPENVLLSELHQKAVDEALQSKNGHLDLFLRFLLGLSLESNQILLQELMIKFRSSSDSSEKTVEYIKKRINNICLPEKSIN---LFYCLNELGDHSLVKEIQQYMDYGTLAETKISCGQWSALVFILLTVEQAMDVFELNKFIGLKKSSDE---------VLRKLLPVIKKSRSAIMDDCNITAEGCAYLASALGSNPSYLRELDLSANKLQDS-------------------------------------------------------------------------------------------------------------------GIKKLSKGLQDSHCKLEKLNLYHCGVTNEGCAALASALKSNPEHLRDLNLSENKIGNLGLTCLSEILKNSLCKLEILRLCQCGITD--CTDLASALISNPEHLRELELSLNKIGDSGVTALCAAFEDPRFKLEKLGLSGCGLTDEGCAALTSALRSNHE-HLRDLDLSGNKVDKEVKGSILQRILEKLNNIQILSV-------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8M6YU37-1", "uniprot_id": "A0A8M6YU37_DANRE", "id": "A0A8M6YU37-1", "name": "", "aln": "------------------------------------------MEDNQTFSDAPVCSNESNPE----------------------------------FEPSCVSMKSDQSMDPPMKFKEGHTSADLSDRLNPPGS----SCVSMKSDWSMDRPIQFKEEHSSADLS----NKSNPGEPSCVSSKS-DQSMGPPINVMEEHS--------------------------------AADLRLDPHLKQNGLRSNLLRKFQCLYEGTAMQGDPTLLNEIYTELYITESDSGEINNKHELRQIETRSRRSATEDTPIQCRDIFTPLPGQDKAIRTVLTKGVAGIGKTVSVQKFIVDWAEEKENQD-IQLIFPLPFREINLMKDRTLSLSDLLQVFFPETKEMEISSEQFKVLFIFDGLDECRVSLDFKCDVKLHDVSESASVDVLLTNLIMGNLLPSALIWITSRPAAADLIPSEFVHR-VTEIRGFNDPQKEEYFRKRIRDQFLADIIIINLKSSRSLHIMCHIPVFCWISATVLEKIFSQAQS-GEIPKTLTQMYTHFLIMQTNIRHEKDYEEEVRDEDMILKLGKLAFEQLVKGNLIFYEEDLRECGLDVTEASVYSGLCTQIFREEFGFYQGKVFCFVHLSIQEHLAALYAHHSLTNKNRNVFKQTKPS--LLSKVLNQKKHDS-----LSVLHQRAVKEASQSKNGHLDLFLRFLLGLSLESSGTLLRELLTQTGSCSYNKEETVQYIKQKIRENRSPERSIN---LFHCLNELGEDSLMQEIQDYLSSGEIKETKLSSSQWSALVYVLLTSEKKMDFFDLSKFIG--PQLRADV-------VLQKLLPVVKESRSVRLGDCKVTDKVCAALASALRLNSSHLTQLDLIGNKLGDS-------------------------------------------------------------------------------------------------------------------GVKLLSDGLKDPHCKLKNLMMRDCGVTDEGCAALASALRSNSTHLTELNLNENNLGDAGVKRLSDGLKGPHCKLEILRLWRCGVRDEGCAALASALSSNSTHLKELELSDNKLGDSGVKLLSDALKDPHCKLEKLRLNGCGVREQGCVSLALALRFNPSSHLTELDLTSNELGKSGVKLLSDLRDDPRYKLRHLACDMFGRIIVSSGGGRLDELLPTTSTET-----------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8N7UUW9-1", "uniprot_id": "A0A8N7UUW9_DANRE", "id": "A0A8N7UUW9-1", "name": "", "aln": "--MDHRGHRDENLPKGRPTFPHRSNPPEPSGVSMKSDRSMHHPLKFKG-----NTGFRVKPP-----------------------------------EPSGVSMKSDRSMHHPLKFKG-------GIDPGFRVNPPEPSGVSMKSDWSMHHPLKFSGGIDP------MFRPPEP----SVSEKS-GQSVDPTLKFSVH-----------------------------------TCHGSSHRKPLQTFRSNLLKKFQCVSEGTARNKSPTLLNEIYTELYITEGDSGEINNEHEVRQIETQSRRSTTEDTPIQCRDIFTALPGQHKAIRTVLTKGVAGIGKTVSVQKFILDWAEEKENQD-VQLIFPLPFREINLMKDRTLSLADLLHVFFPETKEMEISRDGYKVLFIFDGLDECRLSLDFNSGVKLCDISESASVEDLLINLIVGNLLPSALIWITSRPAAADLIPSAFVHR-LTEVRGFTDPQKEEYFRKRIRDQRLADEIIQHLKSCRSLFIMCHIPVFCWISATVLEDMMRRTDI-GEIPKTLTEMYTHFLIIQTSIRHEKHYEKKLKDEEMILKLGKLAFRQLMKGNLIFYEEDLRECGIDESEASVYSGLCTQIFREELGLFQGKVFCFVHLSIQEHLAALYVLLSFLLYERDELSENFRS-----TRPHEFTCHT-----VFDLHQRAVDKALQSRNGHLDLFLRFLLGLSLKSNQTLLKNVLTQVGNISYSQEETVEYIKIRIKLNPSPEKSIN---LFHCLNELGDHSLVNEVQKYVRSGDLSGSRLSSSQWSAVVFILLTSEQ-LDEFNLRRYLTDSEHQTQTQKLQTPDEVLQKLLSVVEASRSAVLINCGVSDEGCAALASVLRSKSSNLRELNLSENKVGDSGVKRLSAGLKDPHCKLEKLRLRCCGVS---------------------------------------------------------DEGCAALASVLKSNSSNLRELDLSWNKVGDSGVKLLSAGLKDPHCKLEKLRLCRCGVSDEGCAALVSVLSSNSSNLRELNLTENKVGDSGVKLLSAGLKE-NSKLEKLWLFICGVSDEGCAALASILRSNSSNLRELDLTGNKVGDSGVKLLSAGLKDPHCKLEKLTLDFCGVSDEGCAALASALRSNSS-NLRELNLFNNNLGVSGVKLLSDLRDDPHYKLETLHISWGFIC-------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "D3ZP31-1", "uniprot_id": "D3ZP31_RAT", "id": "D3ZP31-1", "name": "", "aln": "----------------------------------------------------------------------------------------------------MASFFSDFGL------------------------------MWYLEELNKKEFVKFKEFLKQEILQLRLKQISWT----KVKKASREDLANLLLKHYEEK----------------------------------QAWDMTFKIFQKMNRKDLIERAGREIAGHSKLYQAHLKKKLTHDYARKFNIKAQDLFKQKFTQDDCDR------------FENLLVSKATGKKPHMVFLQGVAGIGKSLMLTKLMLAWSEGIVFQNKFSYIFYFCCQDVKQLKRASLAELISREWPNASAPTAEILSQPEKLLFIIDSLEVMECNMSERESELCDNCTEKQPVSLLLSSLLRRKMLPESSFLISATPETFEKMEDRIECTNVKIITGFNENNIKMYFRSLFQDKNRTLEAFSLVRENEQLFNVCQVPVLCWMVATCIKKEIEKGRDPVFICRRTTSLYTTHIFNLFTPQNAQYPSKK--SQDQLQGLCSLAAEGMWTDTFVFSEEALRRNGILDSDIPTLLDRRILERSKES----ESCYIFLHPSLQEVCAAVFYLLKSHLDHPS--------------------------QDVKSVEALLFT-FLKKAKVQWIFLGCFLFGLLHESEQEKLEMFFG--HQLSQEIKHQLYQCLETISVNEELQEQIDGMKLFYCLFEMEDEAFLMQAMNCMEQINFVAKDYSDVIVAAYCLKHCSTLKKLSFSTQNILSEEQEHSYT-EKLLICWHHMCSVLISSKDIHVLQVKDTNLNETAFWVLYNHLKYPSCTLKVLVVNNVTFLCDNHLFFELIQNQ-RLQHLNLSLTFLSHSDVKLLCDVLNQAECN-------------------------------IEKLMIAACNLSPDDCKVFASVLISSKMLKHLNLSSNNLDK-GISSLCKALCHPDCILKHLVLANCSLSEQCWDYLSEVVRRN-KTLSHLDISSNDLKDEGLKVLCGALTLPDSGLISLSVRHCLITTSGCQDLAEVLRHN-QNLRSLQVSNNKIEDAGVKLLCDAIKQPNCHLENIGLEACELTGACCKDLASAFVHCKT--LWGINLLENALDHSGLVVLFEALKQQKCTLHVLGLRITDFDKETQEFLIAEEEKNPYLSILSNV--------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q3TKR3-1", "uniprot_id": "NAL4C_MOUSE", "id": "Q3TKR3-1", "name": "NACHT, LRR and PYD domains-containing protein 4C", "aln": "----------------------------------------------------------------------------------------------------MASFFSDFGL------------------------------MWYLEELNKKEFMKFKEFLKQEILQLRLKQISWT----EVKKASREDLANLLLKHYEEK----------------------------------KAWDMTFKIFQKMNRKDLMERAGREIAGHSKLYQAHLKKKLTHDYARKFNIKVQDFSKQKFTQDDYDR------------FENFLISKVTAKKPHMVFLQGAAGIGKSLMLTKLMLAWSEGMVFQNKFSYIFYFCCQDVKKMKRASLAELISKEWPKTSAPIEDILSQPEKLLFVIDNLEVMECDMSERESELCDTCTEKQPVRILLSSLLRRKMLPKSSFLISATPETFEKMEGRVECTNVKIVTGFNESNIKMYFRSLFQDKTKTQEIFSLVKENQQLFTVCQVPVLCWMVATCLKKEIEKGRDLVSVCRRTTSLYTTHIFNLFIPQSAQYPSKE--SQAQLQSLCSLAAEGMWTDTFVFGEEALRRNGIMDSDIPTLLDVRILEKSKKS----EKSYIFLHPSIQEVCAAIFYLLKSHMDHPS--------------------------QDVKSIEALIFT-FLKKVKVQWIFFGSFIFGLLHESEQKKLEAFFG--HQLSQEIKRQLYQCLETISGNEELQEQVDGMKLFYCLFEMDDEAFLAQAMNCMEQINFVAKDYSDVIVAAHCLQHCSTLKKLSLSTQNVLSEGQEHSYT-EKLLMCWHHMCSVLISSKDIYILQVKNTNLNETASLVLYSHLMYPSCTLKALVVNNVTFLCDNRLFFELIQNQ-CLQHLDLNLTFLSHGDVKLLCDVLSQEECN-------------------------------IEKLMVAACNLSPDDCKVFASVLISSKMLKHLNLSSNNLDK-GISSLSKALCHPDCVLKNLVLVNCSLSEQCWDYLSEVLRRN-KTLNHLDISSNDLKDEGLKVLCGALSLPDSVLKSLSVRYCLITTSGCQDLAEVLRKN-QNLRNLQVSNNKIEDAGVKLLCDAIKHPNCHLENIGLEACALTGACCEDLASAFTHCKT--LWGINLQENALDHSGLIVLFEALKQQQCTLHVLGLRITDFDKETQELLMAEEEKNPHLSILSSV--------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q96MN2-1", "uniprot_id": "NALP4_HUMAN", "id": "Q96MN2-1", "name": "NACHT, LRR and PYD domains-containing protein 4", "aln": "---------------------------------------------------------------------------------------------------MAASFFSDFGL------------------------------MWYLEELKKEEFRKFKEHLKQMTLQLELKQIPWT----EVKKASREELANLLIKHYEEQ----------------------------------QAWNITLRIFQKMDRKDLCMKVMRERTGYTKTYQAHAKQKFSRLWSSKSVTEIHLYFEEEVKQEECDH------------LDRLFAPKEAGKQPRTVIIQGPQGIGKTTLLMKLMMAWSDNKIFRDRFLYTFYFCCRELRELPPTSLADLISREWPDPAAPITEIVSQPERLLFVIDSFEELQGGLNEPDSDLCGDLMEKRPVQVLLSSLLRKKMLPEASLLIAIKPVCPKELRDQVTISEIYQPRGFNESDRLVYFCCFFKDPKRAMEAFNLVRESEQLFSICQIPLLCWILCTSLKQEMQKGKDLALTCQSTTSVYSSFVFNLFTPEGAEGPTPQ--TQHQLKALCSLAAEGMWTDTFEFCEDDLRRNGVVDADIPALLGTKILLKYGER----ESSYVFLHVCIQEFCAALFYLLKSHLDHPH--------------------------PAVRCVQELLVANFEKARRAHWIFLGCFLTGLLNKKEQEKLDAFFG--FQLSQEIKQQIHQCLKSLGERGNPQGQVDSLAIFYCLFEMQDPAFVKQAVNLLQEANFHIIDNVDLVVSAYCLKYCSSLRKLCFSVQNVFKKEDEHSSTSDYSLICWHHICSVLTTSGHLRELQVQDSTLSESTFVTWCNQLRHPSCRLQKLGINNVSFSGQSVLLFEVLFYQPDLKYLSFTLTKLSRDDIRSLCDALNYPAGN-------------------------------VKELALVNCHLSPIDCEVLAGLLTNNKKLTYLNVSCNQLDT-GVPLLCEALCSPDTVLVYLMLAFCHLSEQCCEYISEMLLRN-KSVRYLDLSANVLKDEGLKTLCEALKHPDCCLDSLCLVKCFITAAGCEDLASALISN-QNLKILQIGCNEIGDVGVQLLCRALTHTDCRLEILGLEECGLTSTCCKDLASVLTCSKT--LQQLNLTLNTLDHTGVVVLCEALRHPECALQVLGLRKTDFDEETQALLTAEEERNPNLTITDDCDTITRVEI", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ..: : : .: . .: . . :. * . . : * :* : * .. ::: . . . :.:. * : : : * : *: :* ****: : *::: *:: :: . : : :::. : :*: . . : :* : ::**::*.:: . :. :. .* ** .*: ::**.: : *: * . : . : **.: : ** : * : : ::. ..*. :*::*::**: .* ::. : . : *.:*: :: . : : : : * .:* . : ... * *: **. *: :: .. . : . : *:* .:** **:: : :. . : . : :: *: ** :. * : * . :. : : : :: :*:** *: : ::: : . : : :* : : : : .: : * : * **. * * :*: *:: *.: * : *. : .. .** : *. * : * *: .: * ::* * :. : : . :. * ", "identical_positions": 84, "similar_positions": 213, "identity": "6.76%" }, { "cls_id": "homologset.agr.MGI:1890520", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q793F9-1", "uniprot_id": "VPS4A_RAT", "id": "Q793F9-1", "name": "Vacuolar protein sorting-associated protein 4A", "aln": "MTT-STLQKAIDLVTKATEEDKAKNYEEALRLYQHAVEYFLHAIKYEAHSDKAKESIRAKCMQYLDRAEKLKDYLRNKEKHGKK--PVKENQS---EGKGSDSDSE-GDNPEKKKLQEQLMGAVVMEKPNIRWNDVAGLEGAKEALKEAVILPIKFPHLFTGKRTPWRGILLFGPPGTGKSYLAKAVATEANNSTFFSVSSSDLMSKWLGESEKLVKNLFELARQHKPSIIFIDEVDSLCGSRNENESEAARRIKTEFLVQMQGVGNNNDGTLVLGATNIPWVLDSAIRRRFEKRIYIPLPEEAARAQMFRLHLGSTPHNLTDANIHELARKTEGYSGADISIIVRDSLMQPVRKVQSATHFKKVCGPSRTNPSVMIDDLLTPCSPGDPGAIEMTWMDVPGDKLLEPVVCMSDMLRSLATTRPTVNADDLLKVKKFSEDFGQES-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8VEJ9-1", "uniprot_id": "VPS4A_MOUSE", "id": "Q8VEJ9-1", "name": "Vacuolar protein sorting-associated protein 4A", "aln": "MTT-STLQKAIDLVTKATEEDKAKNYEEALRLYQHAVEYFLHAIKYEAHSDKAKESIRAKCMQYLDRAEKLKDYLRNKEKHGKK--PVKENQS---EGKGSDSDSE-GDNPEKKKLQEQLMGAVVMEKPNIRWNDVAGLEGAKEALKEAVILPIKFPHLFTGKRTPWRGILLFGPPGTGKSYLAKAVATEANNSTFFSVSSSDLMSKWLGESEKLVKNLFELARQHKPSIIFIDEVDSLCGSRNENESEAARRIKTEFLVQMQGVGNNNDGTLVLGATNIPWVLDSAIRRRFEKRIYIPLPEEAARAQMFRLHLGSTPHNLTDANIHELARKTEGYSGADISIIVRDSLMQPVRKVQSATHFKKVCGPSRTNPSVMIDDLLTPCSPGDPGAIEMTWMDVPGDKLLEPVVCMSDMLRSLATTRPTVNADDLLKVKKFSEDFGQES-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9UN37-1", "uniprot_id": "VPS4A_HUMAN", "id": "Q9UN37-1", "name": "Vacuolar protein sorting-associated protein 4A", "aln": "MTT-STLQKAIDLVTKATEEDKAKNYEEALRLYQHAVEYFLHAIKYEAHSDKAKESIRAKCVQYLDRAEKLKDYLRSKEKHGKK--PVKENQS---EGKGSDSDSE-GDNPEKKKLQEQLMGAVVMEKPNIRWNDVAGLEGAKEALKEAVILPIKFPHLFTGKRTPWRGILLFGPPGTGKSYLAKAVATEANNSTFFSVSSSDLMSKWLGESEKLVKNLFELARQHKPSIIFIDEVDSLCGSRNENESEAARRIKTEFLVQMQGVGNNNDGTLVLGATNIPWVLDSAIRRRFEKRIYIPLPEEAARAQMFRLHLGSTPHNLTDANIHELARKTEGYSGADISIIVRDSLMQPVRKVQSATHFKKVCGPSRTNPSMMIDDLLTPCSPGDPGAMEMTWMDVPGDKLLEPVVCMSDMLRSLATTRPTVNADDLLKVKKFSEDFGQES-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M3AP98-1", "uniprot_id": "A0A8M3AP98_DANRE", "id": "A0A8M3AP98-1", "name": "vesicle-fusing ATPase", "aln": "MTT-STLQKAIELVTKATEEDKAKNYEEALRLYQHAVEYFLHAIKYEAHSDKAKESIRGKCMQYLDRAEKLKDYLKNKDKQGKK--PVKETQS---NDK-SDSDSE-GENPEKKKLQEHLMGAIVMEKPNVRWSDVAGLEGAKEALKEAVILPIKFPHLFTGKRTPWRGILLFGPPGTGKSYLAKAVATEANNSTFFSVSSSDLMSKWLGESEKLVKNLFDLARQHKPSIIFIDEVDSLCGSRNENESEAARRIKTEFLVQMQGVGNNNDGILVLGATNIPWVLDAAIRRRFEKRIYIPLPEEPARSAMFRLHLGNTPHSLTEADLRQLARKTDGYSGADISIIVRDALMQPVRKVQSATHFKKVRGPSRSNSAVIVDDLLTPCSPGDPEAIEMTWMDVPGDKLLEPIVCMSDMLRSLATTRPTVNTEDLLKVKKFTEDFGQEG-", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9Y162-1", "uniprot_id": "Q9Y162_DROME", "id": "Q9Y162-1", "name": "vesicle-fusing ATPase", "aln": "MAAGTTLQKAIDLVTKATEEDRNKNYAEALRLYEHGVEYFLHTIKYEAQGEKAKDSIRAKCLQYLDRAEKLKEYLKKGKKKPIK--EGGESSAKDDKDKKSDSDDEDGDDPEKKKLQSKLEDAIVIEKPKVQWSDVAGLDAAKEALKEAVILPIKFPQLFTGKRIPWKGILLFGPPGTGKSYLAKAVATEANRSTFFSVSSSDLMSKWLGESEKLVKNLFELARQHKPSIIFIDEIDSMCSARSDNENDSVRRIKTEFLVQMQGVGNDTDGILVLGATNIPWVLDSAIRRRFEKRIYIPLPEAHARLVMFKIHLGNTTHVLTEQDLKELAGKTEGYSGADISIVVRDALMEPVRKVQTATHFKRVSGPSPTNHEEIVNDLLVPCSPGDQGAVEMNWMDVPSDKLFEPPVTMRDMLKSLSRTKPTVNEDDLKKLRKFTEDFGQEG-", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P52917-1", "uniprot_id": "VPS4_YEAST", "id": "P52917-1", "name": "Vacuolar protein sorting-associated protein 4", "aln": "MSTGDFLTKGIELVQKAIDLDTATQYEEAYTAYYNGLDYLMLALKYEKNP-KSKDLIRAKFTEYLNRAEQLKKHLESEEANAAKKSPSAGSGSNGGNKKISQEEGEDNGGEDNKKLRGALSSAILSEKPNVKWEDVAGLEGAKEALKEAVILPVKFPHLFKGNRKPTSGILLYGPPGTGKSYLAKAVATEAN-STFFSVSSSDLVSKWMGESEKLVKQLFAMARENKPSIIFIDEVDALTGTRGEGESEASRRIKTELLVQMNGVGNDSQGVLVLGATNIPWQLDSAIRRRFERRIYIPLPDLAARTTMFEINVGDTPCVLTKEDYRTLGAMTEGYSGSDIAVVVKDALMQPIRKIQSATHFKDVSTEDDE------TRKLTPCSPGDDGAIEMSWTDIEADELKEPDLTIKDFLKAIKSTRPTVNEDDLLKQEQFTRDFGQEGN", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*:: * *.*:** ** : * .:* ** * :.::*:: ::*** : *:*: **.* :**:***:**.:*.. . : * . : : * *:.:.* . . ::***: * .*:: ***:::*.*****:.************:***:**.*:* * ****:******************* ***********:***:********:** :**::*********:*:: .:*.:.*.:: ******:****:****:.:* ********** **:*******:*******: ** **.:::*.*. **. : : *. *:****:**:::*:*:**:*:**:*:***** * . *.****** *:**.* *: .*:* ** : : *:*::: *:**** :** * .:*:.*****. ", "identical_positions": 232, "similar_positions": 120, "identity": "52.13%" }, { "cls_id": "homologset.agr.MGI:1890541", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D4A203-1", "uniprot_id": "D4A203_RAT", "id": "D4A203-1", "name": "", "aln": "MSCKTPPVLQELAEDSLLKNQALAVAALDDLPSLFFPSLFKKACRHRLVGIIKAMVQAWPFPCLPLGAMVSRKTAYRRILEIVLYGFDALLFQEVPHRRCKLKVLDLRVMPLKLWNRLPVFGTAGCSENPAVLGHSGTRVKQPVKVLVDMVLKESPLDSTEAFLVQWVDSRSGLVKLCCCKLQIWAMSIYYHRKLLEILDLDSIQELRVYCISNPVCLLNFAPYLGRMRNLRCLILSHLWQAFSMTPVEKQQVITQFTSQFLKLKCLQILHLDTVFFLEGHLDELFWWLKTPLETLSVIDCNLSKSDWIHISEFQCTSQLKHLNLKWVKLTHLSPEPLRILLLKSASTLISLDLEGCQMMDSQLSAILPALRCCTQLTKFNFHGNYISMPILRELAHNVVKQKSHPSKIHFIPSCDHHSGLDFEVISQPHIVFVDVERTTGQQEQVLFYAVCSGEYVL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q99MW3-1", "uniprot_id": "PRAL1_MOUSE", "id": "Q99MW3-1", "name": "Preferentially expressed antigen in melanoma-like protein 1", "aln": "MSCKTPPTLQELAENSLLKNQDLAISALDDIPSLFFPSLFKKACRNRYVGIIKAMVQAWPFPCLPLGAMISRKTAYRRILEIILYGLDALLSQKVPHSRCKLQVLDLRVMPLKLWNRLPVFGTAGCSENPAVVGHSGTEVKQPVKVLVDLVLKESPLDSTESFLVQWVDNRNGLVSLCCCKLQIWAMSMYYHRKLLEILDLDSVQELRMYCISNPVCLLNFAPYLGRMRNLRCLILSHLWQTFSMTPVEKQQVITQFTSQFLKLKCLQILHLDTVFFLEGHLDELFWWLKTPLETLSVIDCNLSKSDWFHISEFQCTSQLKHLNLKWVKLTHLSPEPLRVLLLKSASTLTSLDLEGCQMMDSQLSAILPALRCCTQLTKFNFHGNYISMPILRELAYNVVKQKSQQSKIRFIPSCSHHSGLEFEAISQPHIVFVDVDRTTGEQEQVLFYAICSGEYVL", "tax_id": 10090, "tax_name": "Mouse" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*******.******:****** **::****:**************:* *********************:************:***:**** *:*** ****:*****************************:*****.**********:***********:*******.*.***.************:**************:****:********************************:******************************************************************:******************************:********* **********************************************:*******: ***:*****.*****:**.***********:****:********:*******", "identical_positions": 419, "similar_positions": 33, "identity": "91.48%" }, { "cls_id": "homologset.agr.MGI:1890545", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "F6UK53-1", "uniprot_id": "F6UK53_MOUSE", "id": "F6UK53-1", "name": "", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MNQVVIATTPPLTKELESTALVKPKTSGLLRIEKIPIKYLWVPEFQRLEVTGIASPEERGKGTAILVAGVPGKEELDDTEIPTLHFTGFVHLEALINKCSPSSEYSRPGTPGNLWMESPENAESPGSDDMEVARSMYPFRERSIFRRSWAELLEAPLNSEGLHIIQTEHIHNEENRDMGCNKLTLQEENQVIPLPKDQHFQALQGPFPLLPERPKLQRQRSRSLPRNSEVGGQYLNTPEFKGSAEETPFFPRD-HNLLTEENIKERHSMEGAWQRVIPSHSGEHFPIMPRFDNSSIQGNFGIPEDNSARPRGNMRI-QSNVNTIPMVNVGIPIDNPQVLKG----NTGVPRGSGFGVYMGNSGRPSGHVVSSPLIELSKIGEHQL-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8I5ZYP3-1", "uniprot_id": "A0A8I5ZYP3_RAT", "id": "A0A8I5ZYP3-1", "name": "", "aln": "MAQLFRYFQGDPVATSSPTEVRMWVEELDFSFLSYGEIFESAEINGERLLNITRKQLNELGIVSTDHQDILLQAVARIRKKGKIEEQAMHREDQNIKKMPTRFGKESEQLEHAIDRVLVTISERRLARSLHGTIEQPPHSILTATLELVNIVNTILNILERPPFDCMSEFSSLKNHLINHITLLKYFSEQSDLNHENESDIIDMCKGVTKMCHYIISLPPDLPKPEKQMPRPSPGEDRPPRVQVPITTEPETMSSSLKRKADSPAIQHLSMPATSSILSCDPPVQCTSVPNQGVSESYSSSQRVDSPSDEGAFTLECDKGYKSETEIQNTDSFETLGGSFYYKTLQDLTIIESDTPLVDSGSEKCVIDSDSDRGVVSDFELEEQSKASGSVMWGLDSDTEKSPRDSHSRKRFFKAETCQLDSISIEDLTKTGEHLVRIEQCQMESGSLEHWMPSGSEKSLEESNSERFSDSDNERKKEEKFQMASASIKRLIESEETKMENENLWMIPDSESYSVDSHTEKDRTPISKVHLIQGDETEKPRTKRYMVDSDSEPSETDSDSERCELASAAVKYFMDTQTFHHSSTSNQFPKDSWSESRTVNSDSESPVMSSDSMKYMKKAETCKSTCNLERLKVVHKSESLQSWLDAKRKQLESAHAGYWDSSGKYQFTSIVPQESFGKCQGDLQTFQSITEKNEVGSSSDKHQTQFGNERDQNEPESKRYLRKAEKGLDNEGFQMDKEREGYLVESDHRDSENETHLLEAHRLGARRKENRPPGFWRPIILPPKLAQEKKTEEQKSVQQKDDRFSRIQLTRYKSEDKNVRFKEASSSLSDKQLSQEKLQKKHSYSFSPDSHTFTGERHPRKASRKLSVYKRHCKEYRYSHSCESLKYQISPIPLSFETCTSNVSSFAGNPTSESPKSVTRKKTRRSITYSPDVKTQKCTRCFVEISNSSSHKCTVNSDDSDSDSPLHGQISSYSKYSLHSKTTRHFKTARNRPLSRSLDPQHPVVTRCSLHGEDSKYSIDSTSYLHCESCSALQNLKGSSVTHTISKNTKKIMGQHSTHGHMSAPIRFPQSESKFNLSTQPQNKDTPDDSDIRFISARNIKGEANVEDKLPYKDETDHDDETNTEDERDDETDTEDEDDTKDKKDPKDKSDPDGNDPKDGNSENNTDGNNGSHSSGSSGHMGEPDSSNDGDSKYVTDHKSESDPTIDNANNSDINLKYSTDDLYTNNLGNASDLAECFDHHNNADFKSSTNPASGNKTRTVLDFTSGSINEDTGPRNTTIQENIVYSENIRLLSNSHQNNAIKTESDPSSNPSPQNSYGLPKALEFNTNITPSNATNSIAN--PNYGTKLTSTAIYRHRSALNYYSDVNDVTGFTYKIRSSFVVNSKYFDRKKYAVRPSFALSTITAIDNSNITTRTTAISSQFTAEKIYALDTEYFPRLSHFKSFNIIINPNYNDENIQNVNNSIVIINNNLPATELETNSILSVLKTIYKNISHFIAGTNYPDIFITSEFYEPVELGRAYKVFDNQNIGAPFQVSPGYMDSHNSKYPTGSMDALDAKESGFLKDFSRIQNTIGIKYPPSTFKVLSNQNIPPPSFDVIVEAELPNIVKFAISSGAVNQLFKLSDNYDGGLRAEGASLAAPTWGPEGGRYVGFERSYAVNPAKDLAVRPEQGRTMIPARGRSVSPARGYSERCGRKRAVSLSRGYTERQARPRSLSPFSMHAVSSTQEIALQAARRPPMRHEEEFLLGAAVGLTVKPAEGYDEETSKSATPSPENISDDDEEEEEEEEEEEEEEEEEEEEEEEEEEENENGSSIIRSIINCFMKAKAQNWIDWSWFKRLLPTFFSEEDRHSWSKNQFCAIACTELGHGKCEGWLWHKRASRGISLFSWKKYWFILKHSTLYWFSHLNDTKADGFIYLPEFRIDLAPHCRRNHAFQATHARIKDFYFAGSCLDEMNYWVCQTIQLAFGSSFGDIAANAEYRLASASTYAKCLVDLKRNFPVIWCNYCQEATTIVSVNPNFEYRRTQNISDEFIYFRPINAENQERARKQKQQNPSLASQQPTPEGIHQRDLGLMNQVVTVTTPPPAKELESAALVKPKTSGLLRLEKIPVKSTWVLEFQRLDVTGIASPEERGKGTAILVAGVPGKEELDDTEIPTLHFTGFVHLEVLINKCSPSSEYSRPGTPGNLWMESPENAESPGSDDMEVARSMYPFRERSIFRRSWAELLEAPLNSEGLHILQT--VHNEENTDMGWNKLTPQEESQGIPYPKDQHFQALQGPFPLLPERPKLQRQRSRSLPRYSEVRGQYLNTPEFKANAEETLFFTGD-RSLLTEENIKKRYNMEGDWQRAIPSHSGEQLPIMPRFDNSAIQGNFGIPEDNSARPRGDIRIPQSNVNTIPMVNVGVPVDNPPVLGG----NTEVPRGSGFRVYVGSSGRASRPMVSSPLTELSKIGEHQL-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q03735-1", "uniprot_id": "NAB6_YEAST", "id": "Q03735-1", "name": "RNA-binding protein NAB6", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSNSNSKKPVANYAYRQQQDYNGMNAMVG--------------------NPMMYHPVDFVNGAGQYGPSQHPAYYTNSPLPNIPPTPFDTAYGASLFPSHLLMG------SPFVSSPNMQSGYNSARSSNLKRKAYSRPVSNHNGYNGNSNSNQNNTN----------NGMVTPSNYYRMGRNSFSRNNNSTRNVTHNNNKGCDTRNNSGRRTFARNNIFDDILPEMLLQRPFCINYKVLPTGDDAYRTRSLLIEN-----VDHSIDLHSIVKNFVKSN--------TLESAYLIEGGKSDDSKDVETKNLSILISFLTKGDCLNFYNNILQRLSEFKTFLKSEALNLKFVCLNYDPKCLPTFIESEALTENAEEADITNGSTMISASLHHNIANKDATRSIIIEFKSPVEKSDLFKKKLQFLD---------------------RSKNKRYILESIDLVNTDVPSNQFPEN----YAVLTFLNISMAIEVLDYLKKYSKNLGISKCFYVSLAPLVVSSARSSVANIYEGKTSTHRLSVPSVTAGNNNDSNNNGNNNKSNMSGITTLNN--------------------------------------------------------NSSIGVSVYGHSNMSLTSLSSSVSLNEEIDMLATKLQG-----------------------------------------------VELDGTYLEINYRDYQTPTIEEHSTHLSNVKISKTTENSRQFSQDIPSPLPLNEHMFMNDSNQSNGAIIPQQLIATPSPVSPNLQMNQRVLPNPITQSLEQNFN---------------------------------VSAKVASSMGSDIGNRTIYIGNINP--------------RSKAEDICNVVRGGILQSIKYIPEKKICFVTFIEAPSAVQFYAN----------------------------------------------SFIDPIVLHGNMLRVGWGHYSGPLPKLISLAVTIGASRNVYVS--------------------------------LPEFAFKEKFIHDPQYKKLHETLSLPDAEQLREDFSTYGDIEQINYLSDSHCCWINFMNISSAISLVEEMNKESTVQNESGEVTLKRATEEKFGGRYKG--LLINYGKDRCGNINKNLIAGKNSRFYKKVKRPSYNIRLSKLEEKRRQNEIDEK-------EKAFDKPLNLESLGISLDAHKDNGGGETGTANNTGHENESELEAENENGNETGSFGGLGLAVASSDVKRATS-DETDYEDIFNKSSGSSDSSSDVEVIMHSPSDPEYALKSQTLRSSSQTVINSKRPVKIEDEEEAVGMSQLN---YRSSLRQAPPRAPSTLSYNHSKNNETPMQDIFTNGETANNRKKKRGSFARHRTIPGSDVMAQYLAQVQHSTFMYAANILGASAEDNTHPDE", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * . : *. .. ..: ::: :. . :* .:. : * . :.*. :* :. : :: : : :: ::*. .: .*. ..:: : . : . ..:* * : *: : :: *** *.* * .* . *: ::*.: . :: : . * : * ..::* * . . .:: .: .:.: ....* . . * . *..:.::. . :* : .. *. *.::: :..: . .:. . . : :.:. :.. * . :* * : :* .. : *:.. :.: .:. * :: . * ", "identical_positions": 37, "similar_positions": 146, "identity": "1.51%" }, { "cls_id": "homologset.agr.MGI:1890546", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9H9Z2-1", "uniprot_id": "LN28A_HUMAN", "id": "Q9H9Z2-1", "name": "Protein lin-28 homolog A", "aln": "MGSVS-NQQFAGGCAKAAEEAPEEAPEDAARAADEPQLLHGAGICKWFNVRMGFGFLSMTARAGVALDPPVDVFVHQSKLHMEGFRSLKEGEAVEFTFKKSAKGLESIRVTGPGGVFCIGSERRPKGKSMQKRRSKGDRCYNCGGL-DHHAKECKLPPQPKKCHFCQSISHMVASCPLK-AQQG-PSAQGKPTYFREEEEEIHSPTLLPEAQN", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0ABK0LT56-1", "uniprot_id": "A0ABK0LT56_RAT", "id": "A0ABK0LT56-1", "name": "Protein lin-28 homolog A", "aln": "MGSVS-NQQFAGGCAKAAEKAPEEAPADAARAADEPQLLHGAGICKWFNVRMGFGFLSMTARAGVALDPPVDVFVHQSKLHMEGFRSLKEGEAVEFTFKKSAKGLESIRVTGPGGVFCIGSERRPKGKSMQKRRSKGDRCYNCGGL-DHHAKECKLPPQPKKCHFCQSISHMVASCPLK-AQQG-PSSQGKPVYFREEEEEIHSPTLLPEAQN", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8K3Y3-1", "uniprot_id": "LN28A_MOUSE", "id": "Q8K3Y3-1", "name": "Protein lin-28 homolog A", "aln": "MGSVS-NQQFAGGCAKAAEKAPEEAPPDAARAADEPQLLHGAGICKWFNVRMGFGFLSMTARAGVALDPPVDVFVHQSKLHMEGFRSLKEGEAVEFTFKKSAKGLESIRVTGPGGVFCIGSERRPKGKNMQKRRSKGDRCYNCGGL-DHHAKECKLPPQPKKCHFCQSINHMVASCPLK-AQQG-PSSQGKPAYFREEEEEIHSPALLPEAQN", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q803L0-1", "uniprot_id": "LN28A_DANRE", "id": "Q803L0-1", "name": "Protein lin-28 homolog A", "aln": "MPPANPHLNHTGGCTKTEEEE-------AASSEEDSGSFHGSGVCKWFNVRMGFGFLSMTHREGICLDSPVDVFVHQSKLHMEGFRSLKEGEAVEFTFKRSSKGLESLQVTGPGGAPCVGSEKKPKG--TQKRRSKGDRCFNCGGP-NHHAKECQLPPQPKKCHFCQSISHMVANCPIK-AQQLSPGSQGKSTTSTGEEEDMSHTPLLPESTD", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A0R4IRA3-1", "uniprot_id": "A0A0R4IRA3_DANRE", "id": "A0A0R4IRA3-1", "name": "Protein lin-28 homolog A", "aln": "--------MAEGGCAKTEEEE-------GQAAEEDPRPYHGVGVCKWFNVRMGFGFLSMNTRDGVPLETPVDVFVHQSKLHMEGFRSLKEGESVEFTFKKSSKGLESVRVTGPGGAHCVGSDRRPKGKSVQKRRAKGDRCYNCGGL-DHHAKECKLPPQPKRCHFCQSVAHMVANCPVK-AQQSTQGSQGKSAGQKQEEADQNHS---PPATD", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VRN5-1", "uniprot_id": "LIN28_DROME", "id": "Q9VRN5-1", "name": "Protein lin-28 homolog", "aln": "MENVQLENGLERRTTSQSSTSSAN-PANLASPTEECGCVR-LGKCKWFNVAKGWGFLTPN-------DGGQEVFVHQSVIQMSGFRSLGEQEEVEFECQRTSRGLEATRVSSRHGGSCQGSTYRPRIN----RRTRRMRCYNCGEFANHIASECALGPQPKRCHRCRGEDHLHADCPHKNVTQSHSNSKSISNNSSSSAAQEKSE----EAT-", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :. . . :: : * ****** *:***: . : :****** ::*.***** * * *** :::::***: :*:. * * ** :*: **:: **:*** :* *.** * ****:** *:. *: *.** * . * .::. . . : : ", "identical_positions": 62, "similar_positions": 45, "identity": "29.11%" }, { "cls_id": "homologset.agr.MGI:1890563", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q92558-1", "uniprot_id": "WASF1_HUMAN", "id": "Q92558-1", "name": "Actin-binding protein WASF1", "aln": "MPLVKRNIDPRHLCHTALPRGIKNELECVTNISLANIIRQLSSLSKYAEDIFGELFNEAHSFSFRVNSLQERVDRLSVSVTQLDPKEEELSLQDITMRKAFRSSTIQDQQLFDRKTLPIPLQETYDVCEQPPPLNILTPYRDDGKEGLKFYTNPSYFFDLWKEKMLQDTEDKRKEKRKQKQKNLDRPHEPEKVPRAPHDRRREWQKLAQGPELAEDDANLLHKHIEVANGPASHFETRPQTYVDHMDGSYSLSALPFSQMSELLTRAEERVLVRPHEPPPPPPMHGAGDAKPIPTCISSATGLIENRPQSPATGRTPVFVSPTPPPPPPPLPSALSTSSLRASMTSTPPPPVPPPPPPPATALQAPAVPPPPAPLQIAPGVLHPAPPPIAPPLVQPSPPVARAAPVCETVPVHPLPQGEVQGLPPPPPPPPLPPPGIRPSSPVTVTALAHPPSGLHPTPSTAPGPHVPLMPPSPPSQVIPASEPKRHPSTLPVISDARSVLLEAIRKGIQLRKVEEQREQEAKHERIENDVATILSRRIAVEYSDSEDDSEFDEVDWLE", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8R5H6-1", "uniprot_id": "WASF1_MOUSE", "id": "Q8R5H6-1", "name": "Actin-binding protein WASF1", "aln": "MPLVKRNIDPRHLCHTALPRGIKNELECVTNISLANIIRQLSSLSKYAEDIFGELFNEAHSFSFRVNSLQERVDRLSVSVTQLDPKEEELSLQDITMRKAFRSSTIQDQQLFDRKTLPIPLQETYDVCEQPPPLNILTPYRDDGKEGLKFYTNPSYFFDLWKEKMLQDTEDKRKEKRKQKQKNLDRPHEPEKVPRAPHDRRREWQKLAQGPELAEDDADLLHKHIEVANGPASHYETRPQTYVDHMDGSYSLSALPFSQMSELLTRAEERVLVRPHEPPPPPPMHGAGDAKPTPTCISSATGLIENRPQSPAAGRTPVFVSPTPPPPPPPLPSALSTSSLRASMTSTPPPPVPPPPPPPATALQAPAVPPPPAPLQIAPGVLHPAPPPIAPPLVQPSPPVARAAPVCETVPVHPLPQGEVQGLPPPPPPPPLPPPGIRPSSPVAVAALAHPPSGLHPAPSTAPGPHAPLMPPSPPSQVLPASEPKRHPSTLPVISDARSVLLEAIRKGIQLRKVEEQREQEAKHERIENDVATILSRRIAVEYSDSEDDSEFDEVDWLE", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q5BJU7-1", "uniprot_id": "WASF1_RAT", "id": "Q5BJU7-1", "name": "Actin-binding protein WASF1", "aln": "MPLVKRNIDPRHLCHTALPRGIKNELECVTNISLANIIRQLSSLSKYAEDIFGELFNEAHSFSFRVNSLQERVDRLSVSVTQLDPKEEELSLQDITMRKAFRSSTIQDQQLFDRKTLPIPLQETYDVCEQPPPLNVLTPYRDDGKEGLKFYTNPSYFFDLWKEKMLQDTEDKRKEKRKQKQKNLDRPHEPEKVPRAPHDRRREWQKLAQGPELAEDDADLLHKHIEVANGPASHFETRPQTYVDHMDGSYSLSALPFSQMSELLSRAEERVLVRPHEPPPPPPMHAAGDARPTPTCVSSAAGLIENRPQSPAAGRTPVFVSPTPPPPPPPLPSALSTSSLRASMTSTPPPPVPPPPPPPAPALQAPAVPPPPAPLQIAPGVLHPAPPPIAPPLVQPSPPVARAAPVCETVPVHPLPQGEVQGLPPPPPPPPLPPPGIRPSSPVTVAALAHPPSGLHPTPSPAPGPHAPLMPPSPPSQVLPASEPKRHPSTLPVISDARSVLLEAIRKGIQLRKVEEQREQEAKHERIENDVATILSRRIAVEYSDSEDDSEFDEVDWLE", "tax_id": 10116, "tax_name": "Rat" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "***************************************************************************************************************************************:**********************************************************************************:***************:*****************************:********************.****:* ***:***:***********:***********************************************.**********************************************************************************:*:***********:**.*****.***********:********************************************************************************", "identical_positions": 542, "similar_positions": 16, "identity": "96.96%" }, { "cls_id": "homologset.agr.MGI:1890564", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P53805-1", "uniprot_id": "RCAN1_HUMAN", "id": "P53805-1", "name": "Calcipressin-1", "aln": "MEDGVAG-------------PQLGAAAEAAEAAEARARPG-------VTLRPFAPLSGAAEADEGGG-DWSFID-----------------------------CEMEEVDLQDLPSATIACHLDPRVFVDGLCRAKFESLFRTYDKDITFQYFKSFKRVRINFSNPFSAADARLQLHKTEFLGK-EMKLYFAQTLH-IGSSHLAPPNPDKQFLISPPASPPVGWKQVEDATPVINYDLLYAISKLGPGEKYELHAATDTTPSVVVHVCESDQE-KEEEEE-MERMRRPKPKIIQTRRPEYTPIHLS", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9JHG6-1", "uniprot_id": "RCAN1_MOUSE", "id": "Q9JHG6-1", "name": "Calcipressin-1", "aln": "MEDGVAG-------------PRLG---EVAEAVEARAPRR-------VTLRPFAPFSAAAEGDGGGGGDWSFID-----------------------------CEMEEVDLQDLPSATIACHLDPRVFVDGLCRAKFESLFRTYDKDTTFQYFKSFKRVRINFSNPLSAADARLRLHKTEFLGK-EMKLYFAQTLH-IGSSHLAPPNPDKQFLISPPASPPVGWKQVEDATPVINYDLLYAISKLGPGEKYELHAATDTTPSVVVHVCESDQENEEEEEE-MERMKRPKPKIIQTRRPEYTPIHLS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6IN33-1", "uniprot_id": "RCAN1_RAT", "id": "Q6IN33-1", "name": "Calcipressin-1", "aln": "---------------------------------------------------------------------------------------------------------MHFRDFNYNFSSLIACVANGDVFSESETRAKFESLFRTYDKDITFQYFKSFKRVRINFSNPLSAADARLQLHKTEFLGK-EMKLYFAQTLH-IGSSHLAPPNPDKQFLISPPASPPVGWKQVEDATPVINYDLLYAISKLGPGEKYELHAATDTTPSVVVHVCESDQEEEEEEEEEMERMKRPKPKIIQTRRPEYTPIHLS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9XZL8-1", "uniprot_id": "SRA_DROME", "id": "Q9XZL8-1", "name": "Protein sarah", "aln": "MSDAAKSNNNASADAPDPTTPDATGEADAANAATPTTPRGNHNNNNSANGRSKNKLKSTQNSSGGGSIDKLSPDQDIFINAADGLPNQHPSLPKEGDVDSDTEPEVDADSFDDLPTSIIVTNIHSEVFANPELKHAMEELFRTFSESATFQWLRSFRRLRVNYDNAIAAANARIKLHQYEFNKKTVITCYFAQPVTPVSNKNLQPPAPVKQFLISPPASPPAGWEPREEGEPLVNHDLLAALASLTPGESHELHPQSEDQPAIIVHTAMLAETGPGLQVK---------APIVQTKCPERA-----", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :. .:: :: *. . ** : : :*.****:.:. ***:::**:*:*:*:.*.::**:**::**: ** * :. ****.: :...:* ** * ************.**: *:. *::*:*** *::.* ***.:***. :: *:::**.. : : : . *:**: ** : ", "identical_positions": 70, "similar_positions": 68, "identity": "22.88%" }, { "cls_id": "homologset.agr.MGI:1890574", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A0G2K677-1", "uniprot_id": "A0A0G2K677_RAT", "id": "A0A0G2K677-1", "name": "", "aln": "MRIWPSGGPAGPNRAGPGPATNARREGGAARRASGTASAAGAQALPSPMAQVPGEVDNMEGPAASNNNNPAARWESPDRGWDREPPAAANAAASLFECSRIKALADEREAVQKKTFTKWVNSHLARVGCHIGDLYADLRDGFVLTRLLEVLSGEQLPRPTRGRMRIHSLENVDKALQFLKEQRVHLENVGSHDIVDGNHRLTLGLVWTIILRFQIQVIKIETEDNRETRSAKDALLLWCQMKTAGYPEVNIQNFTTSWRDGLAFNALIHRHRPDLVDLSKLTKSNANYNLQRAFRTAEQHLGLARLLDPEDVNMEAPDEKSIITYVVSFYHYFSKMKALAVEGKRIGKVLDQVLEVDKIIERYEELAAELLAWIHRTVDLISNQKFANSLSGVQQQLQAFTAYCTLEKPVKFQEKGNLEVLLFSIQSKLRAHNRRLFVPREGCGIWDIDKAWGELEKAEHEREAALRAELIRQEKLELLAQRFDHKVAMRESWLNENQRLVSQDNFGYELPAVEAAMKKHEAIEADIAAYEERVQGVAELAQALAAEGYYDARRVAAQRDSVLRQWALLTGLVGARRTRLEQNLALQKVFQEMVYMVDWMEEMQTQLLSRECGQHLVEADDLLQKHGLLEGDIAAQSERVEALNAAALRFS--QLQGYQPCDPQVICNRVNHVHGCLSELQEQAARRRAELEASRSLWALLQELEEAESWARDKERLLEATSG-----SGGAAGTAGGAHDLSSTARLLAQHKILQGELGGRRALLQQALRRGEELAAAGGSVGPGAEPLHLAGLAERAASARRRWQRLEEAAARRERRLQEARALHQFGADLDGLLDWLRDAYRLAAAGDFGHDEASSRRLARQHRALTGEVEAHRGPVGGLRRQLATLGGASGAGPLVVALQVRVVEAEQLFAEVTEVAALRRQWLRDALAVYRMFGEVHACELWIGEKEQWLLAMRVPDSLDDVEVVQHRFESLDQEMNSLMGRVLDVNQTVQELVEGGHPSSDEVRSCQDHLNSRWNRIVELVEQRKEEMSAVLLVENHVLEVAEVRAQVREKRRAVESAP------RAGGALQWRLSGLEAALQALEPRQAALLEEAALLAERFPAQATRLHQGAEELGAEWGALAGAAQACGEAVAAAGRLQRFLRDLDTFLDWLVRAQEAAGAVEGPLPRSLEEADGLLARHAALKEEVDQREEDYARIVAASEALLASDGAELGPG-LALDEWLPHLEVGWHKLLGLWEERREALVQAHVYQLFLRDLCQALAVLRNQEVALSGAELPCTVESVEEAMKRHRDFLTTMELNQQKMQVAVQAAEGLLRQGNAYGEQAQEAVARLLEKSQENQLRAQQWMQKLLDQLVLQHFLRDCHELDGWIHEKMLMARDGTREDSHKLHKRWLRHQAFMAELAQNKEWLEKIEREGQQLMQEKPELAASVRKKLGEIRQCWAELESTTQAKARQLFEASKADQLVQSFAELDKRLLHMESQLQDVDPGGDLATVNSQLKKLQSMESQVEEWCREVGELQAQTAALP--LEQASKELVGERQSAVGERLVRLLEPLQERRRLLLASKELHQVAHDLDDELAWVQERLPLAMLTERGTGLQAVQQHIKKNQGLRREIQAHGPRLEEVLERAGVLASLRSPEAEAVRRGQEQLQSAWTGLREATERRQQTLDAAFQVEQYYFDVAEVEAWLGEQELLMMSEDKGKDEQSTLQLLKKHLQLEQGVENYEESIAQLSRQCRALLEMGHPDSEQISRRQSQVDRLYVALKELGEERRVSLEQQYWLYQLSRQVDELEHWIAEKEVVAGSPELGQDFEHVSVLQEKFSEFASETGTAGRERLAAVNQMVDELIECGHTAAATMAEWKDGLNEAWAELLELMGTRAQLLAASRELHKFFSDARELQGQIEEKRRRLPRLTAPPEPRPSASSMQRTLRAFEHDLQLLVSQVRQLQEGAAQLRTVYAGEHAEAIASREQEVLQGWKELLAACEDARLHVSSTADALRFHSQARDLLSWMDGIAGQIGAADKPRDVSSVEVLMNYHQGLKTELEARVPELTACQELGRSLLLNKSAMADEIQAQLDKLGSRKEEVSEKWDRHWEWLQQMLEVHQFAQEAVVADAWLTAQEPLLQSRELGSSVDEVEQLIRRHEAFRKAAAAWEERFSSLRRLTTIEKLKAEQSKQPPTPLLGRKFFGDPTELAAKAAPLLRPGGYDRGLEPLARRASDTLSAEVRTRVGYVRQELKPERLQPRIDRLPETSGKVEPAAPTAAALDTTDTPGTPAVTEQVRPRPERQELADRAEELPRRRRSERQESTDQPEEAARRRRPERQESADHEGPHSLTLGRYEQMERRRERRERRIERQESSEQETPTRGELVKGKATLADIVEQLQEKEAGPGLPAAVPSLPQPRELPPGRLPNGLEPPERTPRPDRPRARDRPKPRRRPRPREGGEGGGSRRSRSAPAQGGSAPAPPPPPTHTVQHEGFLLRKRELDAN-RKSSNRSWVNLYCVLSKGELGFYKDSKGPASGG--THGGEPLLSLHKATSEVASDYKKKKHVFKLQTQDGSEFLLQAKDEEEMNGWLEAVANSVAEHAEIARWGQTLPTTSSTDEGNPKREGGERRASGRRK", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "E9PX29-1", "uniprot_id": "E9PX29_MOUSE", "id": "E9PX29-1", "name": "Spectrin beta chain", "aln": "------------------------------------------------MAQVPGEVDNMEGPAVSNNNNPSARWESPDRGWDREPPAAANAAASLFECSRIKALADEREAVQKKTFTKWVNSHLARVGCHIGDLYADLRDGFVLTRLLEVLSGEQLPRPTRGRMRIHSLENVDKALQFLKEQRVHLENVGSHDIVDGNHRLTLGLVWTIILRFQIQVIKIETEDNRETRSAKDALLLWCQMKTAGYPEVNIQNFTTSWRDGLAFNALIHRHRPDLVDLSKLTKSNANYNLQRAFRTAEQHLGLARLLDPEDVNMEAPDEKSIITYVVSFYHYFSKMKALAVEGKRIGKVLDQVLEVDKIIERYEELAAELLAWIHRTVDLISNQKFANSLSGVQQQLQAFTAYCTLEKPVKFQEKGNLEVLLFSIQSKLRAHNRRLFVPREGCGIWDIDKAWGELEKAEHEREAALRAELIRQEKLELLAQRFDHKVAMRESWLNENQRLVSQDNFGYELPAVEAAMKKHEAIEADIAAYEERVQGVAELAQALAAEGYYDARRVAAQRDSVLRQWALLTGLVGARRTRLEQNLALQKVFQEMVYMVDWMEEMQTQLLSRECGQHLVEADDLLQKHGLLEGDIAAQSERVEALNAAALRFS--QLQGYQPCDPQVICNRVNHVHGCLSELQEQAARRRAELEASRSLWALLQELEEAESWARDKERLLEATSG-----SGGAAGTAGGAHDLSSTARLLAQHKILQGELGGRRALLQQALRRGEELAAAGGSVGPGAEPLHLAGLAERAASARRRWQRLEEAAARRERRLQEARALHQFGADLDGLLDWLRDAYRLAAAGDFGHDEASSRRLARQHRALTGEVEAHRGPVGGLRRQLATLGGASGAGPLVVALQVRVVEAEQLFAEVTEVAALRRQWLRDALAVYRMFGEVHACELWIGEKEQWLLAMRVPDSLDDVEVVQHRFESLDQEMNSLMGRVLDVNQTVQELVEGGHPSSDEVRSCQDHLNSRWNRIVELVEQRKEEMSAVLLVENHVLEVAEVRAQVREKRRAVESAP------RAGGALQWRLSGLEAALQALEPRQAALLEEAALLAERFPAQATRLHQGAEELGAEWGALAGAAQACGEAVAAAGRLQRFLRDLDTFLDWLVRAQEAAGAVEGPLPRSLEEADGLLARHAALKEEVDQREEDYARIVAASEALLASEGAELGPG-LALDEWLPHLEVGWHKLLGLWEERREALVQAHVYQLFLRDLCQALAVLRNQEVALSGAELPCTVESVEEAMKRHRDFLTTMELNQQKMQVAVQAAESLLRQGNAYGEQAQEAVARLLEKSQENQLRAQQWMQKLLDQLVLQHFLRDCHELDGWIHEKMLMARDGTREDSHKLHKRWLRHQAFMAELAQNKEWLEKIEREGQQLMQEKPELAASVRKKLGEIRQCWAELESTTQAKARQLFEASKADQLVQSFAELDKRLLHMESQLQDVDPGGDLATVNSQLKKLQSMESQVEEWCREVGELQAQTAALP--LEQASKELVGERQSAVGERLVRLLEPLQERRRLLLASKELHQVAHDLDDELAWVQERLPLAMQTERGTGLQAVQQHIKKNQGLRREIQAHGPRLEEVLERAGVLASLRSPEAEAVRRGQEQLQSAWTGLREAAERRQQTLDAAFQVEQYYFDVAEVEAWLGEQELLMMSEDKGKDEQSTLQLLKKHLQLEQGVENYEESIAQLSRQCRALLEMGHPDSEQISRRQSQVDRLYVALKELGEERRVSLEQQYWLYQLSRQVDELEHWIAEKEVVAGSPELGQDFEHVSVLQEKFSEFASETGTAGRERLAAVNQMVDELIECGHTAAATMAEWKDGLNEAWAELLELMGTRAQLLAASRELHKFFSDARELQGQIEEKRRRLPRLTAPPEPRPSASSMQRTLRAFEHDLQLLVSQVRQLQEGAAQLRTVYAGEHAEAIASREQEVLQGWKELLAACEDARLHVSSTADALRFHSQARDLLSWMDGIAGQIGAADKPRDVSSVEVLMNYHQGLKTELEARVPELATCQELGRSLLLNKSAMADEIQAQLDKLGSRKEEVSEKWDRHWEWLQQMLEVHQFAQEAVVADAWLTAQEPLLQSRELGSSVDEVEQLIRRHEAFRKAAAAWEERFSSLRRLTTIEKLKAEQSKQPPTPLLGRKFFGDPTELAAKAAPLLRPGGYDRGLEPLARRASDTLSAEVRTRVGYVRQELKPERLQPRIDRLPETSGKVEPAAPTAAALDTTDTPGTPAATELVRPRSERQELADRAEELPRRRRSERQESVDQPEETARRRRPERQESADHEGPHSLTLGRYEQMERRRERRERRIERQESSEQETPTRGELVKGKATLADIVEQLQEKEAGPGIPAGVPSLPQPRELPPGRLPNGLEPPERTPRPDRPRARDRPKPRRRPRPREGGEGGGSRRSRSAPAQGGSAPAPPPPPTHTVQHEGFLLRKRELDAN-RKSSNRSWVSLYCVLSKGELGFYKDSKGPASGG--THGGEPLLSLHKATSEVASDYKKKKHVFKLQTQDGSEFLLQAKDEEEMNGWLEAVANSVAEHAEIARWGQTLPTTSSTDEGNPKREGGERRASGRRK", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9H254-1", "uniprot_id": "SPTN4_HUMAN", "id": "Q9H254-1", "name": "Spectrin beta chain, non-erythrocytic 4", "aln": "------------------------------------------------MAQVPGEVDNMEGLPAPNNN-PAARWESPDRGWEREQPAASTAAASLFECSRIKALADEREAVQKKTFTKWVNSHLARVGCHIGDLYVDLRDGFVLTRLLEVLSGEQLPRPTRGRMRIHSLENVDKALQFLKEQRVHLENVGSHDIVDGNHRLTLGLVWTIILRFQIQVIKIETEDNRETRSAKDALLLWCQMKTAGYPEVNIQNFTTSWRDGLAFNALIHRHRPDLVDFSKLTKSNANYNLQRAFRTAEQHLGLARLLDPEDVNMEAPDEKSIITYVVSFYHYFSKMKALAVEGKRIGKVLDQVLEVGKIIERYEELAAELLAWIHRTVGLISNQKFANSLSGVQQQLQAFTAYCTLEKPVKFQEKGNLEVLLFSIQSKLRACNRRLFVPREGCGIWDIDKAWGELEKAEHEREAALRAELIRQEKLELLAQRFDHKVAMRESWLNENQRLVSQDNFGYELPAVEAAMKKHEAIEADIAAYEERVQGVAELAQALAAEGYYDIRRVAAQRDSVLRQWALLTGLVGARRTRLEQNLALQKVFQEMVYMVDWMEEMQAQLLSRECGQHLVEADDLLQKHGLLEGDIAAQSERVEALNAAALRFS--QLQGYQPCDPQVICNRVNHVHGCLAELQEQAARRRAELEASRSLWALLQELEEAESWARDKERLLEAAGGGGAAGAAGAAGTAGGAHDLSSTARLLAQHKILQGELGGRRALLQQALRCGEELVAAGGAVGPGADTVHLVGLAERAASARRRWQRLEEAAARRERRLQEARALHQFGADLDGLLDWLRDAYRLAAAGDFGHDEASSRRLARQHRALTGEVEAHRGPVSGLRRQLATLGGASGAGPLVVALQVRVVEAEQLFAEVTEVAALRRQWLRDALAVYRMFGEVHACELWIGEKEQWLLSMRVPDSLDDVEVVQHRFESLDQEMNSLMGRVLDVNHTVQELVEGGHPSSDEVRSCQDHLNSRWNRIVELVEQRKEEMSAVLLVENHVLEVAEVRAQVREKRRAVESAP------RAGGALQWRLSGLEAALQALEPRQAALLEEAALLAERFPAQAARLHQGAEELGAEWGALASAAQACGEAVAAAGRLQRFLHDLDAFLDWLVRAQEAAGGSEGPLPNSLEEADALLARHAALKEEVDQREEDYARIVAASEALLAADGAELGPG-LALDEWLPHLELGWHKLLGLWEARREALVQAHIYQLFLRDLRQALVVLRNQEMALSGAELPGTVESVEEALKQHRDFLTTMELSQQKMQVAVQAAEGLLRQGNIYGEQAQEAVTRLLEKNQENQLRAQQWMQKLHDQLELQHFLRDCHELDGWIHEKMLMARDGTREDNHKLHKRWLRHQAFMAELAQNKEWLEKIEREGQQLMQEKPELAASVRKKLGEIRQCWAELESTTQAKARQLFEASKADQLVQSFAELDKKLLHMESQLQDVDPGGDLATVNSQLKKLQSMESQVEEWYREVGELQAQTAALP--LEPASKELVGERQNAVGERLVRLLEPLQERRRLLLASKELHQVAHDLDDELAWVQERLPLAMQTERGNGLQAVQQHIKKNQGLRREIQAHGPRLEEVLERAGALASLRSPEAEAVRRGLEQLQSAWAGLREAAERRQQVLDAAFQVEQYYFDVAEVEAWLGEQELLMMSEDKGKDEQSTLQLLKKHLQLEQGVENYEESIAQLSRQCRALLEMGHPDSEQISRRQSQVDRLYVALKELGEERRVALEQQYWLYQLSRQVSELEHWIAEKEVVAGSPELGQDFEHVSVLQEKFSEFASETGMAGRERLAAVNQMVDELIECGHTAAATMAEWKDGLNEAWAELLELMGTRAQLLAASRELHKFFSDARELQGQIEEKRRRLPRLTTPPEPRPSASSMQRTLRAFEHDLQLLVSQVRQLQEGAAQLRTVYAGEHAEAIASREQEVLQGWKELLSACEDARLHVSSTADALRFHSQVRDLLSWMDGIASQIGAADKPRDVSSVEVLMNYHQGLKTELEARVPELTTCQELGRSLLLNKSAMADEIQAQLDKLGTRKEEVSEKWDRHWEWLQQMLEVHQFAQEAVVADAWLTAQEPLLQSRELGSSVDEVEQLIRRHEAFRKAAAAWEERFSSLRRLTTIEKIKAEQSKQPPTPLLGRKFFGDPTELAAKAAPLLRPGGYERGLEPLARRASDTLSAEVRTRVGYVRQELKPERLQPRIDRLPEIPGRVEPAALPAAPEDAAETPATPAAAEQVRPRPERQESADRAEELPRRRRPERQESVDQSEEAARRRRPERQESAEHEAAHSLTLGRYEQMERRRERRERRLERQESSEQEMPIRGDLVKGKATLADIVEQLQEKEAGPGLPAG-PSLPQPRELPPGRLPNGLELPERTPRPDRPRARDRPKPRRRPRPREGGEGGGSRRSRSAPAQGGSAPAPPPPPTHTVQHEGFLLRKRELDAN-RKSSNRSWVSLYCVLSKGELGFYKDSKGPASGS--THGGEPLLSLHKATSEVASDYKKKKHVFKLQTQDGSEFLLQAKDEEEMNGWLEAVASSVAEHAEIARWGQTLPTTSSTDEGNPKREGGDRRASGRRK", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q00963-1", "uniprot_id": "SPTCB_DROME", "id": "Q00963-1", "name": "Spectrin beta chain", "aln": "------------------------------------------------MTTDISIVRWDPSQGPGNEYIDEYEYD------------GGNSSSRLFERSRIKALAEERESVQKKTFTKWVNSHLCRVNCRIADLYVDMRDGKHLIKLLEVLSGERLPKPTKGKMRIHCLENVDKALQFLREQRVHLENIGSHDIVDGNASLNLGLIWTIILRFQIQDITIEEVDNKETKSAKDALLLWCQMKTAGYHNVNVRNFTTSWRDGLAFNAIIHKHRPDLVQFEKLSKTNAIHNLNNAFDVAEDKLGLAKLLDAEDVFVEHPDEKSIITYVVTYYHYFSKLKQETVQGKRIGKVVGIAMENDKMVHDYENFTSDLLKWIETTIQSLGEREFENSLAGVQGQLAQFSNYRTIEKPPKFVEKGNLEVLLFTLQSKMRANNQKPYTPKEGKMISDINKAWERLEKAEHERELALREELIRQEKLEQLAARFDRKASMRETWLSENQRLVSQDNFGFDLAAVEAAAKKHEAIETDIFAYEERVQAVVAVCDELESERYHDVKRILLRKDNVMRLWTYLLELLRARRMRLEISLQLQQNFQEMLYILDNMEEIKQLLMTDDYGKHLMGVEDLLQKHSLVEADINILGERVKVVVQNSQKFLSDDPESYKPCDPEIIVSRVQQLEDAYAELVRLAVERRSRLEESRKLWQFYWDTADEENWIKEKEQIVSTDEVG---------------HDLTTVNLMLSKHKALESEITSHDPQLQNVAKVGSELITEG--------HFGADRIKDRLKEILNKWDHLLDLTKYRRQRLENAVEYFQLFADADDVDNWMLDTLRIVSSEDVGRDEANVQSLLKKHKDVADELKNYAEVIDALHKQAESLKLNEAEK---ANVDKRLEAIDNRYKELTELAKLRKQRLLDALSLYKLMSEADGVEQWIKEKTKMLDTMTPGKDIEDVEIMKHRFEGFDKEMNANASRVAVVNQLARQLLHVEHPNSDEILERQNHLNQEWSTLREKAEAKMDDLKSAHGVQTFYIECRETISWIEDKKRILTETDSLEMDLTGVMTLQRRLSGMDRDLAAIQAKLSSLEREANSIEDEHPEEAKIIRERIAQIELIWEQLTQMLKERDSKLEEAGDLHRFLRDLDHFQTWLTKTQTDVASEDT--PTSLPEAEKLLNQHQSIREEIDNYTEDYKNMMEYGERLTSEGSTSDDPQYMFLRERLNALKDGWEELHQMWENRQVLLSQSLDQQLFNRDARQTEVLLSQQEHFLSKDDTPVNLEQAENQLKRHEAFLTTMEANDDKINTLLQVADTLVEKDHFDADKIGKRAENITGRRDDNRQRALDQHEKLKNQVKLHEFLQDLEELAEWVQEKYATSQDESYRSAKTIHSKWTRHQAFEAEIAANKERLFEAEKSAQELSKEKPEFKDVIEPKLKELAKQFDDLEVHTKEKGAMLFDANREVLVQQTCDDIDSYITDLEKQIVSGDTANDLTSVNILMQKQQVIQTQMAVKARQVEEIDKQTEYLQKTVPEEKIEPIVVKKTAVLERFEKIKAPLLERQKALEKKKEAFQFCRDVEDEKLWIDEKLPVANSPDYGNSLFNVHVLKKKNQSLATEIDNHEPRINAICNNGRKLIDEGHEDAKKFEALISDLTQKWQELKDAIENRRKHLLESEKVQQYFFDAQEAESWMSEQELYMMVEDRGKDEISAQNLMKKHENLEQSVEDYANTIRQLGEVARQFSGDDISSGDAVAVKQSQLDKLYAGLKDLAGERRARLNEALQLFMLSREVDDLEQWITDREVVAGSQELGQDFDHVTLLSERFNEFARDTEAVGGERVAKVNGIADNLIQAGHSDSATIAEWKDNLNESWQDLLELIETRTQMLAASRELHKFFHDCKDVLGRILEKQHGVSDELG--RDAGSVSTLQRKHYNFLQDLITLYSQVQQIQEESAKLQDAYAGDKAKEITNREQEVLHAWDNLQAMCDARKQKLADTGDLFRFFNMVRILMIWMEDLVRQMNTSEKPRDVSGVELLMNNHQSLKAEIDTREDNFGACISLGKELLTRNHYASADIKDRLMTLSNSRNALLRRWEERWENLQLILEVYQFARDAAVAEAWLIAQEPYLLSSELGHTIDEVENLIKKHEAFEKSAAAQEERFSALERLTTFELKEMKR----------------------------------------------------------------------------------------------------------------RQELAEEAE---RQRIKEEQEAKAASEAAEQAKR---------------------EAERRDD-----------------------------VDVGASHDDSERGG---------------TPG----------------------------------AGEG----------------------------HEGYVTRKHEWDSTTKKASNRSWDKVYMAAKAGRISFYKDQKGYKSNPELTFRGEPSYDLQNAAIEIASDYTKKKHVLRVKLANGALFLLQAHDDTEMSQWVTSLKAQSDSTAVAASRSQTLPATSQKDE--PKRRS---FFTLKKK", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *: . * . *: .:: ...::: *** *******:***:**************.**.*:*.***.*:*** * :********:**:**:*:****.***********:********:********* *.***:********** *.** **:**:***************** :**::**************:**:******::.**:*:** :**:.** .**::****:***.*** :* ***********::******:* :*:*******:. .:* .*::. **:::::** **. *: :.:::* ***:*** ** *: * *:*** ** **********::***:** *:: :.*:** * **:*** .********* *** ********* ** ***:*.:***:**.************::*.***** *******:** *******.*. :.: * :* *:* :*: ::*.*:* *: * *: *** *** .* **: ****:*::* ***:: *:: : *:**: .:******.*:*.** .***:.: : :* : :.*:****::* .**:::... :** . *..**:.** **.** : : : *.* ::**:::.: ***::. :*::** *:.*: .: . **:. : *.** : * . : :* . .:*::* : : *.:**::* .*: ** *.: :*: *: *:.:: *.*:***. : * ::*: ::.*:: : :..*::* :* .. . :: *: :: : *:**:* **:* * ***::*:::.*... * ** ** : * :* ..::***:::****.:*:***: .** **: .::*:. **.***: . *:***..*. : * .* : :::.:. *:.. :* *. : :.:*:* : .: . :** ****:: * *::.: ::* .** : :..* :* ::: :: * *: : .. : ** *:***:*** * **.::* ... : * ** **: ** :* :::**:*: *** .:: .* * : .:. .* : * * * *: **.:* :** *: * *: *** ** *: .:* :** ** : * .:*..*: :*:*. ****** .::*::. :*.*: *:.:.: .:: : . .: : ::*: ** : :** :*: *:.**:* .** *::** ::* : .. :.:*.:* ***** **:* *** * : *:..*:* :****: :. ** *: : : :** *: *. **:*.: : *: ::*. : .:*.*: . *...**::** ::* * :::*: *:* *:: ** * : . * : ::.** **: :: ** **:: * .** .*..:*::** *::*:**:* .: *..* *: ****.* **: * **:: : :.. * . :*: .. .:* . * *::* *.*:: * : :*:**:**. *.*:*:.**** ** **:**** *: :*:*** :***.**:* ::* **.. .* : . ...: :: :***:*:**..**:*. ***. *:: *: ***:*.:**:**:::****** ******:**::*.*:*.*** :* .* **:* ** :.*:**:.**: :**:*****.***:* :****: **:*:*********** *.::: *:* **:: :. . *.*::**. * :** * ***:*:** :*:*: .***::*: *:.******:.*.:* : *: : :::.*.* :**.. .* *: **:.:. *:.:::******.**:*** **.**:*:::* :: :* .**:.** .: : :*: :* .*.. :: : .:*:.:** ** :***:***::*.**:*** **** * * *** ::****:**::****.*:*** *****:*.****:* : :: *** *:.** *:* *.**: .* : : :* : *** : .*: . ::.* * .** .*** ***:: **:* *:. :*:***** .:* . . *.:.****.** *. *. *** .*::*: *:****.*****:::: :*: *****:*: **. *: :: . . * * .****:**..** ***.. : ::*", "identical_positions": 993, "similar_positions": 744, "identity": "37.79%" }, { "cls_id": "homologset.agr.MGI:1890577", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8VE97-1", "uniprot_id": "SRSF4_MOUSE", "id": "Q8VE97-1", "name": "Serine/arginine-rich splicing factor 4", "aln": "---MPRVYIGRLSYQARERDVERFFKGYGKILEVDLKN---------GYGFVEFDDLRDADDAVYELNGKDLCGERVIVEHARGPRR-------DGSYGSGRSGYG--YRRSGRDKYGPPTRTEYRLIVENLSSRCSWQDLKDYMRQAGEVTYADAHKGRKNEGVIEFVSYSDMKRALEKLDGTEVNGRKIRLVEDKPGSRRRRSYSRSRSHSRSRSRSRHSRKSRSRSGSSKSSHSKSRSRSRSGSHSRSKSRSRSQSRSRSKKEKSRSPSKDNKSRSRSRSPDKSRSKSKDHAEDKLQNNDSAGKAKSHSPSRHDSKS--RSRSQERRAEEERRRSVSRARSQEKSRSQEKSLLKSR--SRSRSRSRSRSKDKRKGRKRSRDESRSRSRS--KSERSRKHSSKRDSKVSSSSSSSKKKKDTDHSRSPSRSVSKEREHAKAESGQRGSRAEGESEAPNPEPRARSRSTSKSKPNVPAESRSRSKSASKTRSRSKSPSRSASRSPSRSRSRSHSRS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "G3V798-1", "uniprot_id": "G3V798_RAT", "id": "G3V798-1", "name": "", "aln": "---MPRVYIGRLSYQARERDVERFFKGYGKILEVDLKN---------GYGFVEFDDLRDADDAVYELNGKDLCGERVIVEHARGPRR-------DGSYGSGRSGYG--YRRSGRDKYGPPTRTEYRLIVENLSSRCSWQDLKDYMRQAGEVTYADAHKGRKNEGVIEFVSYSDMKRALEKLDGTEVNGRKIRLVEDKPGSRRRRSYSRSRSHSRSRSRSRHSRKSRSRSGSSKSSHSKSRSRSRSGSHSRSKSRSRSQSRSRSKKEKSRSPSKDNKSRSRSRSPDKSRSKSKDHAEDKLQNNDSAGKAKSHSPSRHDSKS--RSRSQERRAEEERRSSTSRGHSQEKSLLKSRSRSRSK--VGSRSRSRSKSKDKRKGRKRSREESRSRSRS--KSERSRKHSSKRDSKVSSSSSK-KKKGDTDHSRSPSRSVSKEREHATAEPGQRESRAEGESEGPNPEPRARSRSTSKSKPSLPAESRSRSKSASKTRSRSKSPSRSASRSPSRSRSRSHSRS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q08170-1", "uniprot_id": "SRSF4_HUMAN", "id": "Q08170-1", "name": "Serine/arginine-rich splicing factor 4", "aln": "---MPRVYIGRLSYQARERDVERFFKGYGKILEVDLKN---------GYGFVEFDDLRDADDAVYELNGKDLCGERVIVEHARGPRR-------DGSYGSGRSGYG--YRRSGRDKYGPPTRTEYRLIVENLSSRCSWQDLKDYMRQAGEVTYADAHKGRKNEGVIEFVSYSDMKRALEKLDGTEVNGRKIRLVEDKPGSRRRRSYSRSRSHSRSRSRSRHSRKSRSRSGSSKSSHSKSRSRSRSGSRSRSKSRSRSQSRSRSKKEKSRSPSKE-KSRSRSHSAGKSRSKSKDQAEEKIQNNDNVGKPKSRSPSRHKSKSKSRSRSQERRVEEEKRGSVSRGRSQEKSLRQSRSRSRSKGGSRSRSRSRSKSKDKRKGRKRSREESRSRSRSRSKSERSRKRGSKRDSKAGSSKKKKKEDTDRSQSRSPSRSVSKEREHAKSESSQREGRGESENAGTNQETRSRSRSNSKSKPNLPSESRSRSKSASKTRSRSKSRSRSASRSPSRSRSRSHSRS", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P26686-2", "uniprot_id": "SRR55_DROME", "id": "P26686-2", "name": "Serine-arginine protein 55", "aln": "-MVGSRVYVGGLPYGVRERDLERFFKGYGRTRDILIKN---------GYGFVEFEDYRDADDAVYELNGKELLGERVVVEPARGTARGSNRDRYDDRYGGRRGGGGGRYNEKSSSRYGPPLRTEYRLIVENLSSRVSWQDLKDYMRQAGEVTYADAHKQRRNEGVVEFASLSDMKTAIEKLDDTELNGRRIHLVEDRRGGRS----GGGGGSGRGRSRSSSSR-SRSR--------SRRRSRSRRSSHSRSKSRSRSKSRG---------------GRSKSKSPVKSRSRS-------------------------------RSRSN-----------------------KSRDVSKSK--SKSHSRTRSRSP------KRERD-SRSRSRS----------VSKRES----------------RSRSRSKSIHRD-------------------------SRSRDRSAS-------AENKSRSR----SRSRSASP-KNGNASPDRNNESMDD--", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q01560-1", "uniprot_id": "NOP3_YEAST", "id": "Q01560-1", "name": "Serine/arginine (SR)-type shuttling mRNA binding protein NPL3", "aln": "MSEAQETHVEQLPESVVDAPVEEQHQEPPQAPDAPQEPQVPQESAPQESAPQEPPAPQEQNDVPPPSNAPIYEGEESHSVQDYQEAHQHHQPPEPQPYYPPPPPGEHMHGRPPMHHRQEGELSNTRLFVRPFPLDVQESELNEIFGPFGPMKEVKILNG---FAFVEFEEAESAAKAIEEVHGKSFANQPLEVVYSKLPAKRYRITMKNLPEGCSWQDLKDLARENSLETTFSSVNTRDFDGTGALEFPSEEILVEALERLNNIEFRGSVITVE---RDDNPPPIRRSNRGG-----------------------------FRGRGG------------------------FRGGFRGG-FRGGFSRGGFGGPRGGFGGPRGGYGGYSRGGYG---------GYSRGG--------------YGGSRGGYDSPRGGYD------------------SPRGGYSRGGYGGPRNDYGPPRGSYGGSRGGYDGPRGDYGPPRDAYRTRDAPRERSPTR-", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ..:: *. . : :*. .: : : : . * :: :*. *. **. : * : . : :: **:*. :. . .:*:: : * :. .. : ..:** . .. *:*::..... .: :.:* .: .: . . . . ..* :: . : . . .: .: .* *. . .. : .:. *.*. :. :. . ** . * . **. .* . **. * . . . . . *: . . :.. : . .. ", "identical_positions": 33, "similar_positions": 118, "identity": "6.4%" }, { "cls_id": "homologset.agr.MGI:1890594", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZCM3-1", "uniprot_id": "ABCG4_RAT", "id": "D3ZCM3-1", "name": "ATP-binding cassette subfamily G member 4", "aln": "----------------------------------------------MAEKALEAVGCGLGPGAVAMAVALEDGAEPPVLTTHLKKVENHITEAQR--------------------------------------FSHLPKRSAVDIEFVELSYSVREGP-CWRKRGYKTLLKCLSGKFCRRELIGIMGPSGAGKSTFMNILAGYRESGMKGQILVNGRPRDLRTFRKMSCYIMQDDMLLPHLTVLEAMMVSANLKLS-EKQE--VKKELVTEILTALGLMSCSHTRTALLSGGQRKRLAIALELVNNPPVMFFDEPTSGLDSASCFQVVSLMKSLAHGGRTVICTIHQPSAKLFEMFDKLYILSQGQCIFKGVVTNLIPYLKGLGLHCPTYHNPADFIIEVASGEYG-DLNPMLFRAVQNGLCT------------------------------------MAEKKSSPEKNEVPAHCP-TCPPELDP---------------------------------------------------------IESHT----------FATSTLTQFCILFRRTFLSILRDTVLTHLRFMSHVLIGVLIGLLYLHIGDDASKVFNNTGFLFFSMLFLMFAALMPTVLTCELICLAKMAVFMREHLNYWYSLKAYYLAKTMADVPFQVVCPVVYCSIVYWMTGQPAETSRFLLFSALSIATALVAQSLGLLIGAASTSLQVATFVGPVTAIPVLLFSGFFVSFK---TIPTYLQWSSYLSYVRYGFEGLILTIYGMERGHLTCLED--HCPFRDPQIILHELDVEEAKLYMDFLVLGIFFLALRLLAYLVLRYRVKSER-----------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q91WA9-1", "uniprot_id": "ABCG4_MOUSE", "id": "Q91WA9-1", "name": "ATP-binding cassette subfamily G member 4", "aln": "----------------------------------------------MAEKALEAVGCGLGPGAVAMAVTLEDGAEPPVLTTHLKKVENHITEAQR--------------------------------------FSHLPKRSAVDIEFVELSYSVREGP-CWRKRGYKTLLKCLSGKFCRRELIGIMGPSGAGKSTFMNILAGYRESGMKGQILVNGRPRELRTFRKMSCYIMQDDMLLPHLTVLEAMMVSANLKLS-EKQE--VKKELVTEILTALGLMSCSHTRTALLSGGQRKRLAIALELVNNPPVMFFDEPTSGLDSASCFQVVSLMKSLAHGGRTVICTIHQPSAKLFEMFDKLYILSQGQCIFKGVVTNLIPYLKGLGLHCPTYHNPADFIIEVASGEYG-DLNPMLFRAVQNGLCT------------------------------------MAEKKSSPGKNELPAHCP-TCPPELDP---------------------------------------------------------IESHT----------FATSTLTQFCILFRRTFLSILRDTVLTHLRFMSHVLIGVLIGLLYLHIGDDASKVFNNTGFLFFSMLFLMFAALMPTVLTFPL----EMAVFMREHLNYWYTLKAYYLAKTMADVPFQVVCPVVYCSIVYWMTGQPAETSRFLLFSALAIATALVAQSLGLLIGAASTSLQVATFVGPVTAIPVLLFSGFFVSFK---TIPTYLQWSSYLSYVRYGFEGLILTIYGMERGHLTCLDE--QCPFRDPQIILRELDVEEAKLYMDFLVLGIFFLALRLLAYLVLRYRVKSER-----------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9H172-1", "uniprot_id": "ABCG4_HUMAN", "id": "Q9H172-1", "name": "ATP-binding cassette sub-family G member 4", "aln": "----------------------------------------------MAEKALEAVGCGLGPGAVAMAVTLEDGAEPPVLTTHLKKVENHITEAQR--------------------------------------FSHLPKRSAVDIEFVELSYSVREGP-CWRKRGYKTLLKCLSGKFCRRELIGIMGPSGAGKSTFMNILAGYRESGMKGQILVNGRPRELRTFRKMSCYIMQDDMLLPHLTVLEAMMVSANLKLS-EKQE--VKKELVTEILTALGLMSCSHTRTALLSGGQRKRLAIALELVNNPPVMFFDEPTSGLDSASCFQVVSLMKSLAQGGRTIICTIHQPSAKLFEMFDKLYILSQGQCIFKGVVTNLIPYLKGLGLHCPTYHNPADFIIEVASGEYG-DLNPMLFRAVQNGLCA------------------------------------MAEKKSSPEKNEVPAPCP-PCPPEVDP---------------------------------------------------------IESHT----------FATSTLTQFCILFKRTFLSILRDTVLTHLRFMSHVVIGVLIGLLYLHIGDDASKVFNNTGCLFFSMLFLMFAALMPTVLTFPL----EMAVFMREHLNYWYSLKAYYLAKTMADVPFQVVCPVVYCSIVYWMTGQPAETSRFLLFSALATATALVAQSLGLLIGAASNSLQVATFVGPVTAIPVLLFSGFFVSFK---TIPTYLQWSSYLSYVRYGFEGVILTIYGMERGDLTCLEE--RCPFREPQSILRALDVEDAKLYMDFLVLGIFFLALRLLAYLVLRYRVKSER-----------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A2BFT1-1", "uniprot_id": "A2BFT1_DANRE", "id": "A2BFT1-1", "name": "", "aln": "----------------------------------------------MAEKTLEP-----GSVSIPMEETKRAGGDAAMLT-HLKKVENHITEAQR--------------------------------------FSHLPRRSTVDLEFTELSYTIREGP-CWRRRGFKALLKCLSGKFCSRELIGIMGPSGAGKSTLMNILAGYRETGMKGQILVNGRPRDLRTFRKMSCYIMQDDMLLPHLTTREAMMVSANLKLN-ENME--VKKELVNEILTALGLQECAQTRTISLSGGQCKRLAIALELVNNPPVMFFDEPTSGLDSASCFQVVSLMKSLAQGGRTIICTIHQPSAKLFEMFDKLYILSQGQCIYKGTVPYLIPYLKNLGLHCPTYHNPADFIIEVASGEYG-DLNPVLFEAVQGGLCS------------------------------------DDSKKNSSDKNDPTTSCPSQCYPDSGY---------------------------------------------------------IEKHT----------FATSTLTQFCILFKRTFITICRDVVLTHLRVMSHLCIGVLIGLLYLNIGNDASKVFNNTGFLFFSMLFLMFAALMPTVLTFPL----EMGVFIREHLNYWYSLKAYYLAKTMADIPFQVICPIMYCSIVYWMTEQPPEAGRYLLFMALSTSTALVAQSLGLLIGAASTSLQVATFVGPVSAIPVLLFSGFFVNFD---TIPKYLQWSSYVSYVRYGFEGVILSIYGMNRSELECPGI--VCKFQKPEEVLQLLDVEDAKLYVDFMVLGVFFLVLRLATYFVLRYKVKSER-----------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VQY4-1", "uniprot_id": "Q9VQY4_DROME", "id": "Q9VQY4-1", "name": "", "aln": "MNELQASSVPLVDKCSSHAVILPAAKSPNRVSDSAATTAPNAVLYTSGNMSLSTLSTGSGNPNPNPNASTNSRQEPVPLLSQLKLTNDLKQNSHGSQNNLCNGGLGSNNHALAPKVANNSGGSPNGQKKGTIALSHLPQRPPVDIEFCDISYSVTDS----HRRGFKTILKSVSGKFRNGEITAIMGPSGAGKSTLMNILAGYKTAQLSGSVLINSKERNLRRFRKLSCYIMQDDVLIANLTVREAMMVAANLKLG-KNMISYAKVVVVEEILETIGLKESVNTLTCNLSGGQRKRLSIALELVNNPPVMFFDEPTSGLDSSTCFQLISLLRSLARGGRTIVCTIHQPSARLFEKFDHLYLLAQGQCVYEGRVKGLVPYLSSLGYECPSYHNPADYVLEVASGEYG-DAVPKLVDAVKSGACKKYAHKDYVLTLAQKGCNNDIIKGSGSGAENAMAILTLEDEKPPLEDRQLEPSIPVDDPAELKPPKLETQQSQNSDCSVVNMPTNAVDDSCSFSSSKGTQNAVGGSGSGGPSAVVGCMTSLLDSHESVVTLPNKTGFPTSGWTQFWILLKRSFRTILRDKMLTHMRLFSHVIVGAIIGMIYYDVGNEASKIMSNAGCIFFVSLFTTFTAMMPTILTFPT----EMSVFVREHLNYWYSLKAFYFAKTIADMPFQIVFSSVYVLVVYYLTSQPMELERVSMFVLICVLNSLVAQSLGLLIGAG-MNIETGVFLGPVTTIPTILFSGFFVNFD---TIPGYLQWVTYVSYVRYGFEGAMVAIYGMDRAKMQCNQM--YCHYRVPKKFLEEMSMDNALFWVDAVALIGIFFALRIIAYFVLRWKLHMIR-----------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q8IPV3-1", "uniprot_id": "Q8IPV3_DROME", "id": "Q8IPV3-1", "name": "ABC transporter domain-containing protein", "aln": "----------------------------------------------MNQYSWKQFLE-----NNNLLGTAGAGQLKAQIVPAQPKT-----------------------------------------------LQHLPKRPAVDLAFHNLTYRVKEG----NRSNAKTILKGVSGRLRSGELTAIMGPSGAGKSTLLNILSGYKTSSIEGSVTMNGAERNLSAFRKLSAYIMQDNQLHGNLTVQEAMTVATNLKLS-KKFSKPEKHSMIDDILLTLSLSEHRYTMTRNLSGGQKKRLSIALELVSNPPIMFFDEPTSGLDSSTCFQCIHLLKMLAAGGRTVICTIHQPSARLFEMFDQLYTLADGQCVYQGSTKQLVPFLSTLNLECPSYHNPASYVIEVSCGEHG-DHTRKLVDAIDNGKRDVRSSADYAGLKARN------------------DLVKVQNLKAILDKNDASSVSGRKYEDNLTLNNGLLNGMVNDIVKEGNVSSALVTTNERGDAMIDVEKSVN--------CTTALLTEEITSPER---------YPTSQFHQFWVVLKRTLLFSYRDWTLMYLRLFAHLLVGFLIGALYYDIGNDGAKVLSNLGFLFFNMLFLMYTSMTITILSFPL----EMPVLLKENFNRWYSLKSYYLAISVADLPFQAIFCVIYVSIVYYFTSQPWELFRFSMFLSACLLISFVAQSVGLVVGAA-MNVQNGVFLAPVMSVPFLLFSGFFVSFD---AIPVYLRWITYLSYIRYGFEGTALATYGYGREKLRCFQT--YCHFKSPITTLEELDMVNANFTLDIVALIVIFVVLRISAYLFLRWKLKTVR-----------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VL61-1", "uniprot_id": "Q9VL61_DROME", "id": "Q9VL61-1", "name": "ABC transporter domain-containing protein", "aln": "---MATPREQFLFGSDNGVAGLGLGIEIGEVTSSRVYNSTTVPVGNSGGWRNAQSSVTPPPIPTPPQVNYTNGNEPSKQPPLEPVVEEEVHFDTD-------------------------------------ALNNLPAREPVDMEFKELSLTVKLG----FNRGSKEILHNVCGKFPGSQLIAIMGPSGAGKSTLLDALSGFKTTGVDGSILLNGRRRDLPSFRRMSCYITQDDRLQPLLTVNENMHIAADLKLG-QTVSYEEKESRIEDILLLLGLYNHDQTLTMRLSGGQKKRLSIAMELINNPTVMFLDEPTTGLDSSSCTKVLELLKKLTSQGRTIICTIHQPTAKLFQIFDQVYVLSAGNCVYQGSTQKLVPFLQSVDLPCPMYHNPADYIIELACGEYGYDKVDTLKLATENGSCLT----------------------------------WFHNPSAVLRAEVLMRKYPIPKKTKSRS-----------------------------------------------------------------------LEDTSYSNQCSVLLRRGFIKAKRDTTMTHLRIGVNIAVAALFGAMYDHTGREGSRVLDNYNLLFAILMHHSMTTMMLTVLTFPM----DISILIKEHFNRWYSLKAYYTAMTLVDLPISIISCFFFTVIVYLWSYQPMEWIRFFMFFSISLLTVFVGHSFGLMIGAW-FDVVNGTFLAPVLTIPMMMFAGFGVTLR---DLPSYLRWGSHISYLRYGLEGFISAIYGLDRGTLACEEAP-YCHYRYPKKFLEEITMRGDQFWNDVIALGVMILVFRFVSYVVLKAKIKSIR-----------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "M9PBX3-1", "uniprot_id": "M9PBX3_DROME", "id": "M9PBX3-1", "name": "ABC transporter domain-containing protein", "aln": "--------------------------------------------------------------MEKLTQEFALRTMP-----------------------------------------------------------DFATSSPFNIIFEDLYYRVEVG----KDREKKSVLKGIKGTFKSGELTAIMGPSGAGKSSLMNILTGLTKSGVSGKIEIG-------KARKLCGYIMQDDHFFPYFTVEETMLMAATLKISNQCVSLKEKRTLIDYLLNSLKLTKTRQTKCSNLSGGQKKRLSIALELIDNPAVLFLDEPTTGLDSSSSFDTIQLLRGLANEGRTIVCTIHQPSTNIYNLFNLVYVLSAGRCTYQGTPQNTVMFLSSVGLECPPYHNPADFLLECANGDYG-DQTEALAEAAKDIRWR------------------------------------YDQQLMQGEDADAPSETQVAKFNESQSPGQVQVQVQKIEIQN------------------------------------------MESSKD----LTKHTYPPTEYMRLWLLIGRCHLQFFRDWTLTYLKLGIHVLCSILIGLFFGDSGSNATKQISNVGMIMIHCVYLWYTTIMPGILRYPA----EIEIIRKETFNNWYKLRTYYLATIITSTPVHIIFSTVYITIGYLMTDQPVEMDRFVKYLLSAVVVTICADGLGVFLGTV-LNPVNGTFVGAVSTSCMLMFSGFLILLN---HIPAAMRFMAYISPLRYALENMVISLYGNQRGQLICPPTEFYCHFKNAVTVLRQFGMEDGDFGHNILMILIQIAIFKVLSYFTLKHKIKTN------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VPJ7-1", "uniprot_id": "Q9VPJ7_DROME", "id": "Q9VPJ7-1", "name": "ABC transporter domain-containing protein", "aln": "----------------------------------------------METASSVKGSTTSQISSLQYSSDINADSLEPDQSEDFQTVLG---------------------------------------------LKYLPSWPAVNLQFSELCYVVPDQT---NASKTKTILRRVNGMFHSHELTAIIGPSGAGKTTLLNLLAGFGAVCESGEILVNNSPRDMRVFRKMSRYIMQTDVLDSQFTVLEMMILAANLKLG-KELNLKQKLEVIDEILGMLRLKDTLNTMAQKLSGGERKRLCIALELVNNPPVIFLDEPTTGLDDLSSSQCIALLKVLAAGGRTVICSIHTPSAKIFEMLDAVYVLAEGQCVYQGKGSNIVPFLKNFGLCCPITYNPADFIIEVACLEYGGSYHEPMVEAVGNGKVARWSPP------------------------------AVEGETTTTKTDTTSGASSFYERDQFDEEISP----------------------------------------------------------------KLLEAKCSWWLQYKLLLVRMLIQMWRDKSYIKLKFYMNIVLALLVGSLYFGMGTSASKALFNFGFMFTIVIAYLYLPMMPVLLYFPT----EINLLKREYNNQWYRLSSYYAAMVTSKLPSMFILAVIYLSIVYLMSSQPLEWFRFAMLFTIAFVTALTSDSFGLLISSR-LSLVNAMFMGPVLAVPLILLSIYGIGYGGGTYISPLMRFLMHLSYLRHSMEGLVASLYDYGRADTICEDTEIFCSFKKSKVLLAFLGFENMHYLWSLSCLMSFYLLFTVAAYFMIRLRLKHSEVSPIFAYVIQLLTKYFNFTSYNY", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VTL3-1", "uniprot_id": "Q9VTL3_DROME", "id": "Q9VTL3-1", "name": "ABC transporter domain-containing protein", "aln": "----------------------------------------------MEQSQ------------------------------------------------------------------------------------NLLAKQSKNVEFQDVYYTVKERKNFWRVTGERRILNGVSGSFRNGQLSAIMGPSGAGKSSLLNAISGFRRDGVTGNIKMK---------RDNACYITQDDHHQTLLTVEELMNLACDLKLK----NRHKKAEIMTDILENLHLNHRRNVTAEKLSGGERKRLSIALELVDNPNIFFLDEPTSGLDEVTAAQCIRLLQAMAYEGRTIVCTIHQPSATIYNYFDSIYVLAKGQCVYQGSPRATIPFLRLAQLDCPRHYSPSDYIIELVDAEDG-HLVPALSDLTENGKLIYVVS---------------------------------QSEQLAPQQAVTTMFLEQQKRPFLPAFFAGSAASTDGTLIGG-------------------------------------TSALLEQVKAFSKRLHTDRRDVCGFRQFIVLMRIMLLRITRARLALTIQLFHHLLCGLFFGLIFFQLGNQGARMFDHLKFCIGAVLMIVYTQVMVPILSYPA----EVKLVKKETFNRWYTLTPYYMALTVSRLPVQVLLNITFMAVTYWMSGLPQQFWRFCIFVAVGLMISLVAEGMGLAIGAT-FSITNGSVVGPMLIAPLMGLAVYGFDFAP--QVSGGMQLLMKFSYVRVGVVSLVLAVFGFQREELDCDAI--YCHFSDPRVLLKFLDVEKVSMLHQFGLLAMLMLFFRVMMYISLRKRCYA-------------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . :: * :: : : :*. : * : :: .*:*******::::: ::* *.: : * . ** * : :*. * * :: **: * : :* : * . ****: ***.**:**:.** ::*:****:***. :. . : *:: :: ***::*:** *:: ::: :: :* *: *.* ::* : :* ** :.*:.:::* : * : . : ::: * ::. :: . :.* :: * ..:: : : : : : :* .: :. :* * ** * .:* * * : : : * : * : * : ....*: :.: . . .:..: : :: : . :. :: .* :* .. . : :. * * * : . * : . . : : . *. :: : ", "identical_positions": 88, "similar_positions": 163, "identity": "10.1%" }, { "cls_id": "homologset.agr.MGI:1890596", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P57680-1", "uniprot_id": "EVC_MOUSE", "id": "P57680-1", "name": "EvC complex member EVC", "aln": "-----MTCTKDARLQLGREALQAAPTLLVPAVLLGGVLGLGLGLWLGCRASHLRARLQKDDRKRLLGSSEPPAQSLRDTGSQAKARRRQRETTRDEDAPEVCEPSLSGNITAFALKARVVYPINQKFRPLADGSSHPSLHENLTQAAAILPHLPHQPAEASPASSLGSLSQAGKEDGSSSSSMRSTYSDDRILQCAFLRVGSFPEILACESVDIDLCVCSLHLKDLLQVDTALRQEKHLMFIQILKACLLDFFPKKKPDDELCQKVLSKQEHDLEELEKGLQARLANTEMLGTGDSGYVSLADVERKERELSEQLIDNMGAFWKQMESIQPTLMDQFKCSSSKARQFMMTLTGRMIVAEGLLHDSQDLHVLDTLERTMGRSHLARMVEFLRTQIQEETKCRLAAISRGLELLTVQGQLSGRQKEELLTQQHKAFWEEAERFGREFTQRGKDLVQASQARQAEAAAELTQTQEEERRSFLADSQLTSDPGEFLKAFHEVLERQRLTRSDQEGDEDTRITEAMAALCQELYCSTMGTFQKFVDSLFLKTLPEVTSLPVAECETLRQQVQEQAARQLGQADRFRRRQWGLLCDLLEQDKRVWLEEGTLSTVLQRQLRDHHESTIHGVLSRFSGLSEESSRGILQGHELLLCSALRRLALRGTTITALAQMRLSGKKRLLQELHEQLALEQGVSPCLEEHQWQLLRALEARIQEEAARLEDEAQQTGLRLQQQLLAEAQEAGRLLQLHMERVIGQALLVHARNVASKGRTREKEDFKRTLVETVVESVYVTSTSVNRLVQAHYQAVGKLLQAHEEQLLQRLKTLQGERINAYKLWKKQEFSDPSLESQTADGTHGASQGVQQRMLSQQKRLLDQFTKHQQGRLNSQRQKAQELDQLQAQLETQLQEAEQTLISELSTLARVPLPENKPFSNKRGLPEKPVRTKRKKPPPREREDLGTPNDDHLALADHTTGPLSTTYSASPPIRVHSGGRLDQQDSEAGDGESTSKILQKGSNL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "G3V706-1", "uniprot_id": "G3V706_RAT", "id": "G3V706-1", "name": "", "aln": "-----MTCRRDARLQLGREALQAAPTLLVPAVLLGALLGLGLGLWLGCRARRLRARLQKDDTKHLLRSSEPPAQSLRDT--SSKARRRQRETTRDEDAPEVCEPSLSGNITAFALKARVVYPINQKFRPLADGSSHPSLHENLTQAAAILPHLPHQPAEASPASSLGSLSQAGKEDGSSSSSMQSTYSDDRVLQCAFLRVGSFPEILAYESVDIDLCVCSLHLKDLLQVDAALRQEKHLMFLQILKACLLECFPKKKPEEELYQKILSKQEHDLEELEKGLQARLANTEMLGTGDSGYISLADVERKERELSEQLIDNMGAFWKQMESMQPILMDQLKCSSSKARQLMMTLTGRMIVAEGLLHESQDLHVLDTLERTMGRAHMARIVEFLRTQIQEETKCRLAAISRGLELLTVQGQLSGRQKEELLTQQHKAFWEEAECFGREFMQRGKDLVQVSQAHRAEAVAELTRAQEEERRIFLADTQPTSDPEEFLKAFHEVLERQRLTRSDQEGEEDTRITEAMAALCQELYCGTMETFQKFVDTLFLKTLPEVSSLPVAECEALRQQVQEQAARQLGQADRFRRRQWGLLCDLLEQDKRVWLEECTLSTVLQRQLRDHHESTIHGVLSRFSGLSEESTRGILQGHELLLCSALRRLALRGTTITALAQMRLSGKKRLLQELHEQLALEQGVSPCLEEHQWQLLRALEARILEETARLEDEAQQTALRLQQQLLAEAQEAGQLLQLHSERAIGQALLVHARNVASKGRTRDKEDFKRTLVETVVESVYVTSTSVNRLVQVHYQGIGKLLQAHEEQLLQRLKTLQDERINAYKLWKKQEFSDPPSESQTPGGTHGAPQAVQQRMTSQRKKLLDQFTKHQQGRLNSQRQKAQELDQLEAQLETQLQEAEQTLISELATLARVPLAENKPFSNKRGLPEKPVRTKRKKPPPREREDLGLPNDDHPALADHSTGPLSAVYSASPPILVHSNGKLGQQDGEACDGENTRKILQKRSNL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P57679-1", "uniprot_id": "EVC_HUMAN", "id": "P57679-1", "name": "EvC complex member EVC", "aln": "MARGGAACKSDARLLLGRDALRPAPALLAPAVLLGAALGLGLGLWLGCRAGRQRTRHQKDDTQNLLKNLESNAQTPSETGSPSRRRKREVQMSKDKEAVDECEPPSNSNITAFALKAKVIYPINQKFRPLADGSSNPSLHENLKQAV-----LPHQPVEASPSSSLGSLSQGEKDDCSSSSSVHSATSDDRFLSRTFLRVNAFPEVLACESVDVDLCIYSLHLKDLLHLDTALRQEKHMMFIQIFKMCLLDLLPKKKSDDELYQKILSKQEKDLEELEKGLQVKLSNTEMSGAGDSEYITLADVEKKEREYSEQLIDNMEAFWKQMANIQHFLVDQFKCSSSKARQLMMTLTERMIAAEGLLCDSQELQALDALERTMGRAHMAKVIEFLKLQVQEETRCRLAAISHGLELLAGEGKLSGRQKEELLTQQHKAFWQEAERFSREFVQRGKDLVTASLAHQVEGTAKLTLAQEEEQRSFLAEAQPTADPEKFLEAFHEVLERQRLMQCDLEEEENVRATEAVVALCQELYFSTVDTFQKFVDALFLQTLPGMTGLPPEECDYLRQEVQENAAWQLGKSNRFRRQQWKLFQELLEQDQQVWMEECALSSVLQTHLREDHEGTIRGVLGRLGGLTEESTRCVLQGHDLLLRSALRRLALRGNALATLTQMRLSGKKHLLQELREQRALEQGSSQCLDEHQWQLLRALEARVLEEASRLEEEAQQTRLQLQQRLLAEAQEVGQLLQQHMECAIGQALLVHARNAATKSRAKDRDDFKRTLMEAAVESVYVTSAGVSRLVQAYYQQIGRIMEDHEERKLQHLKTLQGERMENYKLRKKQELSNPSSGSRTAGGAHETSQAVHQRMLSQQKRFLAQFPVHQQMRLHAQQQQAGVMDLLEAQLETQLQEAEQNFISELAALARVPLAESKLLPAKRGLLEKPLRTKRKKPLPQERGDLGVPNNEDLASGDQTSGSLSSK-------------RLSQQESEAGDSGNSKKMLKRRSNL", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :* **** ***:**:.**:**.******. ************* : *:* **** :.** . *. **: :* :: *:*: : ::*::* : ***. ..*********:*:***************:*******.**. *****.****:********. *:* *****::*: ****.*. :****.:***:** ****:***: ********::*:*******:**:**:* ***: :****.::** **:*****:**********.:*:**** *:*** *::*****:**** ******** ****** .:* *:**:*********:***** ***.***** :**:*:.**:*******:*:*:::***: *:****:*******:*****: :*:******************:*** *.*** ******* .* *::.*..*:** :****:* ***::* *:** :**:*********** :.* * :*:.* ***:.******* .*: *******:***:*** ::.** **: ***:***:** ***:::****:** *: :*****::**:** :**:*** :**:.**.**:***.*:.**:***:* :****:*** **********.::::*:********:*****:** ***** * **:*************: **::***:***** *:***:*******.*:*** * * .***********.*:*.*:::::******:*:.********:.*.****.:** :*:::: ***: **:*****.**:: *** ****:*:*. *:*..*:* :.*.*:*** **:*::* **. *** **::*:*:* :* *:************.:****::******.*.* :. **** ***:******* *:** *** **::. * .*:::*.**: :*.**:.** *. .: *:*:: ***", "identical_positions": 642, "similar_positions": 241, "identity": "63.56%" }, { "cls_id": "homologset.agr.MGI:1890602", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P60520-1", "uniprot_id": "GBRL2_HUMAN", "id": "P60520-1", "name": "Gamma-aminobutyric acid receptor-associated protein-like 2", "aln": "MKWMFKEDHSLEHRCVESAKIRAKYPDRVPVIVEKVSGSQIVDIDKRKYLVPSDITVAQFMWIIRKRIQLPSEKAIFLFVDKTVPQSSLTMGQLYEKEKDEDGFLYVAYSGENTFGF", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P60521-1", "uniprot_id": "GBRL2_MOUSE", "id": "P60521-1", "name": "Gamma-aminobutyric acid receptor-associated protein-like 2", "aln": "MKWMFKEDHSLEHRCVESAKIRAKYPDRVPVIVEKVSGSQIVDIDKRKYLVPSDITVAQFMWIIRKRIQLPSEKAIFLFVDKTVPQSSLTMGQLYEKEKDEDGFLYVAYSGENTFGF", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P60522-1", "uniprot_id": "GBRL2_RAT", "id": "P60522-1", "name": "Gamma-aminobutyric acid receptor-associated protein-like 2", "aln": "MKWMFKEDHSLEHRCVESAKIRAKYPDRVPVIVEKVSGSQIVDIDKRKYLVPSDITVAQFMWIIRKRIQLPSEKAIFLFVDKTVPQSSLTMGQLYEKEKDEDGFLYVAYSGENTFGF", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P38182-1", "uniprot_id": "ATG8_YEAST", "id": "P38182-1", "name": "Autophagy-related protein 8", "aln": "MKSTFKSEYPFEKRKAESERIADRFKNRIPVICEKAEKSDIPEIDKRKYLVPADLTVGQFVYVIRKRIMLPPEKAIFIFVNDTLPPTAALMSAIYQEHKDKDGFLYVTYSGENTFGR", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "** **.::.:*:* .** :* :: :*:*** **.. *:* :*********:*:**.**:::***** **.*****:**:.*:* :: *. :*::.**:******:******** ", "identical_positions": 65, "similar_positions": 36, "identity": "55.56%" }, { "cls_id": "homologset.agr.MGI:1890613", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q3B8N8-1", "uniprot_id": "PESC_RAT", "id": "Q3B8N8-1", "name": "Pescadillo homolog", "aln": "MGGLEKKKYERGSATNYITRNKARKKLQLSLPDFRRLCILKGIYPHEPKHKKKVNKGSTAARTFYLIKDIKFLLHEPIVNKFREYKVFVRKLRKAYGKSEWNAVERLKDNKPSYKLDHIVKERYPTFIDALRDLDDALSMCFLFSTFPRTGKCHVQTIQLCRRLTVEFMHYVIAARALRKVFLSIKGIYYQAEVLGQPIVWIAP--YAFSHDHPTDVDYRVMATFTEFYTTLLGFVNFRLYQSLNLHYPPKIE----------SQAQAEMKVS-----------EDTYALDSESSMEKLAALSASLAR-VVVPA-VEEAEADEFPTDGE-VTAQEEDRRKELEAQ------------EKHKKLFEGLKFFLNREVPREALAFIIRSFGGDVSWDKSL-CIGATYDSTDSGITHQIVDRPGQQTPIIGRYYVQPQWVFDCVNARLLLPVAEYFPGVQLPPHLSPFVSEKEGDYIPPEKLKLLALQRGEDPGNLEEEEEDEDDEGDDSEGDG-----------------------DVAVENEEEVVEAESEEEEE--AHLSALEQQRLGGK--KPQVMAGTVKLEDRQRLAQEEESEAKRLAIMMMKKREKYLYQKIMFGK------------RRKIREAN----KLAEKRKAHDDAVRSEKKAKRTRPV", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9EQ61-1", "uniprot_id": "PESC_MOUSE", "id": "Q9EQ61-1", "name": "Pescadillo homolog", "aln": "MGGLEKKKYERGSATNYITRNKARKKLQLSLPDFRRLCILKGIYPHEPKHKKKVNKGSTAARTFYLIKDIKFLLHEPIVNKFREYKVFVRKLRKAYGKSEWNAVERLKDNKPCYKLDHIVKERYPTFIDALRDLDDALSMCFLFSTFPRTGKCHVQTIQLCRRLTVEFLHYVITARALRKVFLSIKGIYYQAEVLGQPIVWIAP--YAFSHDHPTDVDYRVMATFTEFYTTLLGFVNFRLYQSLNLHYPPKLE----------GQAQAETKIS-----------EDTYALDSESSMEKLAALSASLAR-VVVPA-IEEAEADEFPTDGE-VTAQEEDRKKELEAQ------------EKHKKLFEGLKFFLNREVPREALAFIIRSFGGDVSWDKSL-CIGATYDVTDSCITHQIVDRPGQQTPIIGRYYVQPQWVFDCVNARLLLPVAEYFPGMQLPPHLSPFVSEKEGDYIPPEKLKLLALQRGEDPGHLEEEEEEDED--DDNEGD-------------------------VAAENEEEDVEVESEEEEEEEVHLSALEQHRLEEK--KPQVMAGTVKLEDKQRLAQEEESEAKRLAIMMMKKREKYLYQKIMFGK------------RRKIREAN----KLAEKRKAHDDAVRSEKKAKRTRPV", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O00541-1", "uniprot_id": "PESC_HUMAN", "id": "O00541-1", "name": "Pescadillo homolog", "aln": "MGGLEKKKYERGSATNYITRNKARKKLQLSLADFRRLCILKGIYPHEPKHKKKVNKGSTAARTFYLIKDIRFLLHEPIVNKFREYKVFVRKLRKAYGKSEWNTVERLKDNKPNYKLDHIIKERYPTFIDALRDLDDALSMCFLFSTFPRTGKCHVQTIQLCRRLTVEFMHYIIAARALRKVFLSIKGIYYQAEVLGQPIVWITP--YAFSHDHPTDVDYRVMATFTEFYTTLLGFVNFRLYQLLNLHYPPKLE----------GQAQAEAKAG-----------EGTYALDSESCMEKLAALSASLAR-VVVPATEEEAEVDEFPTDGE-MSAQEEDRRKELEAQ------------EKHKKLFEGLKFFLNREVPREALAFIIRSFGGEVSWDKSL-CIGATYDVTDSRITHQIVDRPGQQTSVIGRCYVQPQWVFDSVNARLLLPVAEYFSGVQLPPHLSPFVTEKEGDYVPPEKLKLLALQRGEDPGNLNESEEEEEED-DNNEGDG-----------------------DEEGENEEEEEDAEAGSEKEEEARLAALEEQRMEGK--KPRVMAGTLKLEDKQRLAQEEESEAKRLAIMMMKKREKYLYQKIMFGK------------RRKIREAN----KLAEKRKAHDEAVRSEKKAKKARPE", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P79741-1", "uniprot_id": "PESC_DANRE", "id": "P79741-1", "name": "Pescadillo", "aln": "MGGLQKKKYESGSATNYITRNKARKKLSLSLADFRRLCILKGIYPHEPKHKKKVNKGSTAARTYYLLKDIRFLLHEPIVGKFREYKIFVRKLRKAYGKAEWSAVERLKENKPGYKLDHIIKERYPTFIDALRDVDDALSMCFLFSTFARTGKCHVQTIQLCRRLSVEWMNYIISSRSLRKVFLSIKGIYYQAEVLGQTITWIVP--YQFAHNHPTDVDYRVMATFTELYTTLLGFVNFRLYQTLNLVYPPKLD----------GQGEISLKAEF----------EEDYALESESYTEKLSALSASLAR-MVASVEEEEAELDHFPTEGE-DQEKMEVREKMEQQQ------------SKQKKLFEGLKFFLNREVPRESLAFVIRCFGGEVSWDKSL-CIGSTYEATDETITHHIVDRPSMDKQYINRYYIQPQWVYDSVNAKIQLPVEEYFLGVTLPPHLSPFVEETEGDYVPPEKLKLMALQRGEKP----QAEEDEEEEGEEEEDD---------------------------EEDEEDDEQSEDEEEAEEEANLAEMEEKRSQGKSLSVKVTPGKAKAENRARAAEEEKAEEKRLAIMMMKKKEKYLYDKIMFGK------------KRKVREAN----KLAAKRKAHDDASKADKKKKKKKC-", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VL96-1", "uniprot_id": "PESC_DROME", "id": "Q9VL96-1", "name": "Pescadillo homolog", "aln": "MR--RPKKYESGEATQYISRRAALRKLQLSLNDFRRLCILKGVYPREPKHRRRAQKGSSEIKVLYHTKDIRFLLHESIVWTLRDYKIFAKKSNRDRAIKDFRNLKRRLALFPEIKLDHIVKERYPTFIDALKDLDDCLTLLFLFSTFPSLHLIPREQSNLCRRLTIEFLHYVIASKSLRKVFISIKGYYFQAEIKGQKVTWIVPHYYPFKPQSRQEVDFKVMSIFVEFYTIMLGFTNFRLFHGLNLAYPPQFP----------SSVLQDSEESL----------KDEASFVS----DRIAALNFELLRTDKVQEDEEELDIDMELLEQDGDSKRIIKMKQEAQEV------------SRLRTLFKGLKFFINREVPREPLVILIRSFGGKVSWDSSI-FAGSTYDEGDETITHQIVDRPSITTQYISRDYIQPQWVFDCVNQRQLLPTNKYFIGETLPPHLSPFVDSKRDSYIPPEEKALLDPSLIETHAQSDDDSEDEAQEEEETVDQELLDAQLQLAYQQETAEYKKYGGPDGVNEDEEDPDDEDDNEDDDEEEEELDEKTKRLQEEKQKMSVQSGKVHKVNK-RQVHKAEVDEHRLQARMVKPRHRNLFRKLIREKQTKEKEEWLLRKKRRTIEANEKEARKTAKREARKEAAAAAAKASKLGK-", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P53261-1", "uniprot_id": "PESC_YEAST", "id": "P53261-1", "name": "Pescadillo homolog", "aln": "MR--IKKKNTRGNARNFITRSQAVRKLQVSLADFRRLCIFKGIYPREPRNKKKANKGSTAPTTFYYAKDIQYLMHEPVLAKFREHKTFARKLTRALGRGEVSSAKRLEENRDSYTLDHIIKERYPSFPDAIRDIDDALNMLFLFSNLPSTNQVSSKIINDAQKICNQWLAYVAKERLVRKVFVSIKGVYYQANIKGEEVRWLVP--FKFPENIPSDVDFRIMLTFLEFYSTLLHFVLYKLYTDSGLIYPPKLDLKKDKIISGLSSYILESRQEDSLLKLDPTEIEEDVKVESLDASTLKSALNADEANTDETEKEEEQEKKQEKEQEKEQNEETELDTFEDNNKNKGDILIQPSKYDSPVASLFSAFVFYVSREVPIDILEFLILSCGGNVISEAAMDQIENKKDIDMSKVTHQIVDRPVLKNKVAGRTYIQPQWIFDCINKGELVPANKYLPGEALPPHLSPWGDAIGYDPTAPVE----------------EGEEEESESESESEDQ-------------------------VEEEDQEVVAGEEDDDDDEELQAQKELELEAQGIKYSETSEADKDVNKSKNKKRKVDEEEEEKKLKMIMMSNKQKKLYKKMKYSN-----------AKKEEQAEN---LKKKKKQIAKQKAKLNKLDSKK----", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* ** *.* ::*:* * :**.:** *******:**:**:**:::::.:***: . * ***::*:**.:: .:*::* *.:* : . : :* .****:*****:* **::*:**.*.: ****.:. : : .::: ::: *: : :****:**** *:**:: *: : *:.* : * : :**:::* * *:*: :* *. ::*: .* ***:: .. . . : . * :**. . . . *: . : : : : : . .**..: *::.**** : * ::* . **.* : :: . : . :**:***** . .* *:****::*.:* :*. :*: * *******: . .* : : .*:: : .: .: *::* : .: : : . : . : .. : . : : ::* *:. :.: *: *: : ::. * : *: *:..* . .: ", "identical_positions": 142, "similar_positions": 184, "identity": "21.26%" }, { "cls_id": "homologset.agr.MGI:1890614", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9D0T2-1", "uniprot_id": "DUS12_MOUSE", "id": "Q9D0T2-1", "name": "Dual specificity protein phosphatase 12", "aln": "MLEAQGSNHGCERQAPTASPASSAG------------HAVEVRPGLYLGGAAAVAEPGHL-REAGITAVLTVDSE-PAFPAGAGFEGLRSLFVPALDKPETDLLSHLDRCVAFIG-----------------QARSEGRAVLVHCHAGVSRSVAVVMAFIMKTDQLTFEKAYDILRTVKPEAKVNEGFEWQLKLYEAMG-YEVDTSSAFYKQYRLQKVTEKCPKLWNLP------QELFAVDPTT--ISQGLKDDILYKCRKCRRSLFRHSSILGHS---------------------------------EGSGPIAFAHKRTAPSSVLTTGSQAQ----CTSYFIEPVQWMESTLLG--VMDGQLLCPKCSAKLGSFNWY-GEQCSCGRWITPAFQIHKNRVDEMKMLPVLGSQTKKL-------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9JIM4-1", "uniprot_id": "DUS12_RAT", "id": "Q9JIM4-1", "name": "Dual specificity protein phosphatase 12", "aln": "MLEVQSSNHGCERQAPTTSPASSAG------------HAVEVRPGLYLGGAAAVAGPDYL-REAGITAVLTVDSE-PAFPAGAGFEGLQSLFVPALDKPETDLLSHLDRCVAFIG-----------------QARSEGRAVLVHCHAGVSRSVAVVTAFIMKTEQLTFEKAYENLQTIKPEAKMNEGFEWQLKLYEAMG-HEVHTSSAVYKQYRLQKVTEKYPELRNLP------RELFAVDPTT--VSQGLKDDILYKCRKCRRSLFRRSSILDHS---------------------------------EGSGPVAFAHKRTGLSSVLTTGNQAQ----CTSYFIEPVQWMESALLG--VMDGQLLCPKCSAKLGSFNWY-GEQCSCGRWITPAFQIHKNRVDEVKTLPALGSQTKKP-------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9UNI6-1", "uniprot_id": "DUS12_HUMAN", "id": "Q9UNI6-1", "name": "Dual specificity protein phosphatase 12", "aln": "MLEAPGPSDGCELSNPSASRVSCAG------------QMLEVQPGLYFGGAAAVAEPDHL-REAGITAVLTVDSEEPSFKAGPGVEDLWRLFVPALDKPETDLLSHLDRCVAFIG-----------------QARAEGRAVLVHCHAGVSRSVAIITAFLMKTDQLPFEKAYEKLQILKPEAKMNEGFEWQLKLYQAMG-YEVDTSSAIYKQYRLQKVTEKYPELQNLP------QELFAVDPTT--VSQGLKDEVLYKCRKCRRSLFRSSSILDHR---------------------------------EGSGPIAFAHKRMTPSSMLTTGRQAQ----CTSYFIEPVQWMESALLG--VMDGQLLCPKCSAKLGSFNWY-GEQCSCGRWITPAFQIHKNRVDEMKILPVLGSQTGKI-------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F1QYI8-1", "uniprot_id": "F1QYI8_DANRE", "id": "F1QYI8-1", "name": "Dual specificity protein phosphatase 12", "aln": "--------------------------------------MIPVASGLYIGSVSDLKDAESL-SAAGITHILTVDSE------EASVTGFNTKFIRALDDESTDLLSRLDDCTSFISEALST------------QADSKSAAVLVHCHVGQSRSAAVVTAYLMKTQHLTLQEAYSKLQNIKPDVKMNEEFLDQLALYELMD-CKVDTTSPVYKQFRLKKITEKYPELQNVP------KDVFAVDP-----AQTQNAEAVYRCRKCRRTLFRHSSILSHC---------------------------------VGSGASAFSHKKTRIVSS-SAEDETQ----CTSYFIEPVQWMEQALLG--VMDGQLLCPKCSSKLGSFNWY-GEQCSCGRWVTPAFQMHKNRVDEIKHISISALK-----------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VWF4-1", "uniprot_id": "DUSK4_DROME", "id": "Q9VWF4-1", "name": "Dual specificity protein phosphatase MPK-4", "aln": "MEQSQSQRQAWPSSSAGGGKAQDSGVLTREDFDGGPVSIDEVDTGLFLGNLTAATHMETL-RSFKITHILTLDSV-PLPQHILEASFLTTKYIQIADMPREDILQHLEGCVDFIS-----------------SALAQQGNVLVHCYFGVSRSSSTVIAYMMKRHNLDFLPAYELVKAKRRFVQPNAGFVSQLKLFRRMG-CKIDPNCQRYKIHRLRLAGEQMRKAKILP------QSFHSVVRPDPDITRENPEPIVFRCRRCRRVLASKSHVLEHKPRDRPPQEVVPKEKEEVAAAKLPAQSHDQAENHHGARMLEQLSERIRQSSLGSPGHESTPNYCRSILFVEPIAWMHRIMLN--TQG-RLYCPKCEQKLGNFSWINACKCPCGETMTPAFYLIPSKVELSKAVQNVQTTV----------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q02256-1", "uniprot_id": "PVH1_YEAST", "id": "Q02256-1", "name": "Tyrosine-protein phosphatase YVH1", "aln": "----------------MAGNANSVD-----------EEVTRILGGIYLGGIRPIIDHRPLGAEFNITHILSVIKF-QVIPEYLIRKGYTLKNIPIDDDDVTDVLQYFDETNRFIDQCLFPNEVEYSPRLVDFKKKPQRGAVFAHCQAGLSRSVTFIVAYLMYRYGLSLSMAMHAVKRKKPSVEPNENFMEQLHLFEKMGGDFVDFDNPAYKQWKLKQSIKLDPSGSELVSNSGMFKDSESSQDLDKLTEAEKSKVTAVRCKKCRTKLALSTSFIAHDPP-------------------------------SKESSEGHFIKRAANSHRIIDIQESQAN--CSHFFIEPLKWMQPELQGKQELEGKFSCPGCSSKVGGYNWK-GSRCSCGKWVIPAIHLQTSKVDQFPLQSTALPNMVNFESEKVNR", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : *:::*. * ** :*:: . : * *:*. :: **. . .: *:.** * *** : : *::* * : * :: : .: * * ** *:. *. :. ** :*: : . : :. : :*::** * : .: * :: :: : *:**: **. : . :: ** *. *:*.:.* . :*.**. : **: : .:*: ", "identical_positions": 53, "similar_positions": 76, "identity": "12.44%" }, { "cls_id": "homologset.agr.MGI:1890615", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P60571-1", "uniprot_id": "PANX2_RAT", "id": "P60571-1", "name": "Pannexin-2", "aln": "MHHLLEQSADMATALLAGEKLRELILPGS-QDDKAGALAALLLQLKLELPFDRVVTIGTVLVPILLVTLVFTKNFAEEPIYCYTPHNFTRDQALYARGYCWTELRDALPGVDASLWPSLFEHKFLPYALLAFAAIMYVPALGWEFLASTRLTSELNFLLQEIDNCYHRAAEGRAPKIEKQIQSKGPGITEREKREIIENAEKEKSPEQNLFEKYLERRGRSNFLAKLYLARHVLILLLSVVPISYLCTYYATQKQNEFTCALGASPDGPVGSAGPTVRVSCKLPSVQLQRIIAGVDIVLLCFMNLIILVNLIHLFIFRKSNFIFDKLHKVGIKTRRQWRRSQFCDINILAMFCNENRDHIKSLNRLDFITNESDLMYDNVVRQLLAALAQSNHDTTPTVRDSGIQTVDPSINPAEP---EGSAEPPVVKRPRKKMKWIPTSNPLPQPFKEQLAIMRVENS-KTEKPKPVRRKTATDTLIAPLLDAGARAAHHYKGSGGDTGP----SSAPPAASEKKHTRHFSLDVHPYILGSKKAKTEAVPPALPASRSQEGGFLS-QTEECGLGLAAAPTKDAPLPEKEIPYPTESALP---SGGPFHVCSPPTAS--AAASLSPSSLGKADPLTILSRNATHPLLHIS-TLYEAREEEEGGPCAPSDMGDLLSIPPPQQILIATFEEPRTVVSTVEF", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q6IMP4-1", "uniprot_id": "PANX2_MOUSE", "id": "Q6IMP4-1", "name": "Pannexin-2", "aln": "MHHLLEQSADMATALLAGEKLRELILPGS-QDDKAGALAALLLQLKLELPFDRVVTIGTVLVPILLVTLVFTKNFAEEPIYCYTPHNFTRDQALYARGYCWTELRDALPGVDASLWPSLFEHKFLPYALLAFAAIMYVPALGWEFLASTRLTSELNFLLQEIDNCYHRAAEGRAPKIEKQIQSKGPGITEREKREIIENAEKEKSPEQNLFEKYLERRGRSNFLAKLYLARHVLILLLSVVPISYLCTYYATQKQNEFTCALGASPDGPVGSAGPTVRVSCKLPSVQLQRIIAGVDIVLLCFMNLIILVNLIHLFIFRKSNFIFDKLNKVGIKTRRQWRRSQFCDINILAMFCNENRDHIKSLNRLDFITNESDLMYDNVVRQLLAALAQSNHDTTPTVRDSGIQTVDPSINPAEP---DGSAEPPVVKRPRKKMKWIPTSNPLPQPFKEQLAIMRVENS-KTEKPKPVRRKTATDTLIAPLLDAGARAAHHYKGSGGDSGP----SSAPPAASEKKHTRHFSLDVHPYILGTKKAKTEAVPPALPASRSQEGGFLS-QTEECGLGLAAAPTKDAPLPEKEIPYPTEPALPGLPSGGSFHVCSPPAAP--AAASLSPGSLGKADPLTILSRNATHPLLHIS-TLYEAREEEEGGPCAPSDMGDLLSIPPPQQILIATFEEPRTVVSTVEF", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q96RD6-3", "uniprot_id": "PANX2_HUMAN", "id": "Q96RD6-3", "name": "Pannexin-2", "aln": "MHHLLEQSADMATALLAGEKLRELILPGA-QDDKAGALAALLLQLKLELPFDRVVTIGTVLVPILLVTLVFTKNFAEEPIYCYTPHNFTRDQALYARGYCWTELRDALPGVDASLWPSLFEHKFLPYALLAFAAIMYVPALGWEFLASTRLTSELNFLLQEIDNCYHRAAEGRAPKIEKQIQSKGPGITEREKREIIENAEKEKSPEQNLFEKYLERRGRSNFLAKLYLARHVLILLLSAVPISYLCTYYATQKQNEFTCALGASPDGAAG-AGPAVRVSCKLPSVQLQRIIAGVDIVLLCVMNLIILVNLIHLFIFRKSNFIFDKLHKVGIKTRRQWRRSQFCDINILAMFCNENRDHIKSLNRLDFITNESDLMYDNVVRQLLAALAQSNHDATPTVRDSGVQTVDPSANPAEP---DGAAEPPVVKRPRKKMKWIPTSNPLPQPFKEPLAIMRVENS-KAEKPKPARRKTATDTLIAPLLDR---SAHHYKGGGGDPGPGPAPAPAPPPAPDKKHARHFSLDVHPYILGTKKAKAEAVPAALPASRSQEGGFLS-QAEDCGLGLAPAPIKDAPLPEKEIPYPTEPARAGLPSGGPFHVRSPPAAP--AVAPLTPASLGKAEPLTILSRNATHPLLHIN-TLYEAREEEDGGPRLPQDVGDLIAIPAPQQILIATFDEPRTVVSTVEF", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M6YTH1-1", "uniprot_id": "A0A8M6YTH1_DANRE", "id": "A0A8M6YTH1-1", "name": "Pannexin", "aln": "MQNILEQNLDMATALLAGEKLKELIMPGSTQDEKGGVLAGLMVQLKLELPFDRVVTIGTVIIPILLVTLVFTRNFAEESIYCYTPHNFTRDQALYARGYCWTELRDAVPGVDPELRPSLFEHKFLPYALLAFAGIMYIPALGWEFMASTRLTSELNFLLQEIDNCYHRAAEGRAPKIEKQIQSKGPGITERERREIIENAEKEKSPEQNLFEKYLERRGQSNFLAKLYLARHLAIICLSSIPITYLSAYYARQRQNEFTCALGGPPD-TSSIPELRLNVNCKLPAVQLQRIMAAVDIALLCTMNLIILLNLLHLFVVRKSNFVFDKLHKVGIKTRRRWQKSPFCDINILAMFCNENRDHIKSLNRLDFITNESDLMYDNVVRQLLAALAQSNHDATPTVRDSGIQTIDPSMDPSVLGVGELGGEPSVIKRPRKKMKWIPTSNPLPQSFKEPLTLTRLENSIKAEKPKPVRRKNVADSIIAPLLDS---KSTQYPPTSKDTYN-----------TQKKHSLNLSLDVHPYMLTIQKAETVN-PEPPPVEHSISSVYIEGPHTVVHVSSTLTEKKESPPLSTTTAFSTATLPTNSYLNGGTASMPPPLDSPKVIGPLNQETEPESQPVP-FSRNPSLPLLSIHHTLYEKDEDDQN----------------------RRLARPGELIAAGEC", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*:::***. ************:***:**: **:*.*.**.*::*****************::**********:*****.****************************:****..* *****************.***:*******:**********************************************:**************************:************: *: ** :**:**.:*** *:*********..** . . . :.*.****:******:*.***.*** ******:**:***:.*****:****:********:*::* ****************************************************:********:**:*** :*: : ..**.*:******************.*** *:: *:*** *:*****.***..:*::****** : :* . *. .:***: ::*******:* :**:: * . *..:* .. ::. :. : : *::* .. .:.* . . .* .** . . ..*. : :::*:. :***.: *** * **** *:::. : .* :::: * ", "identical_positions": 425, "similar_positions": 135, "identity": "61.59%" }, { "cls_id": "homologset.agr.MGI:1890616", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "F1M987-1", "uniprot_id": "F1M987_RAT", "id": "F1M987-1", "name": "Signal peptide, CUB and EGF-like domain-containing protein 1", "aln": "MGAAAVRWHLCLLLALGARGQLVGGSGLPGAVDVDECSEGTDDCHIDAICQNTPKSYKCLCKPGYKGEGKQCEDIDECENDYYNGGCVHDCINIPGNYRCTCFDGFMLAHDGHNCLDVDECQDNNGGCQQICVNAMGSYECQCHSGFFLSDNQHTCIHRSNEGMNCMNKDHGCAHICRETPKGGVACDCRPGFDLAQNQKDCTLTCNYGNGGCQHSCEDTDTGPMCGCHQKYALHADGRTCIEKDEAAIERSQFNATSVADVDKRVKRRLLMETCAVNNGGCDRTCKDTATGVRCSCPVGFTLQPDGKTCKDINECLMNNGGCDHFCRNTVGSFECGCQKGHKLLTDERTCQDIDECSFERTCDHICINSPGSFQCLCHRGYILYGTTHCGDVDECSMNNGSCDQGCVNTKGSYECVCPPGRRLHWNRKDCVEMSGCLSRSKASAQAQLSCGKVGGVENCFLSCLGQSLFMPDSETSYILSCGVPGLQGKAPPKRNGTSSSVG--PGCSDAPTTPIRQKARFKIRDAKCHLRPRSQERAKDTLRH-------PLLDNCHVTFVTLKCDSSKKRRRGRKSPSKEVSHITAEFEVEMKVEEASGSCEADCMRKRAEQSLQAAIKTLRKSIGRHQFYVQVSGTEYEVAQRPAK-APEGTGTCGIGQILQDGKCVPCAPGTYFSSEPGQCVPCVSGTYQDMEGQLSCTPCPSSEGLGLAGARNVSECGGQCSPGFFSEDGFKPCQACPVGTYQPEPGRTGCFPCGGGLLTKQTGTASFQECEAKVHCSPGHHYNTTTHRCIRCPVGTYQPEFGQNHCISCPGNTSTDFDGSTNVTHCKNQHCGGELGDYTGYIESPNYPGDYPANAECVWHIAPPPKRRILIVVPEIFLPIEDECGDVLVMRKSASPTSVTTYETCQTYERPIAFTSRSRKLWIQFKSNEANSGKGFQVPYVTYDEDYQQLIEDIVRDGRLYASENHQEILKDKKLIKALFDVLAHPQNYFKYTAQESKEMFPRSFIKLLRSKVSRFLRPYK", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q6NZL8-1", "uniprot_id": "SCUB1_MOUSE", "id": "Q6NZL8-1", "name": "Signal peptide, CUB and EGF-like domain-containing protein 1", "aln": "MGAAAVRWHLYLLLALGARGRLVGGSGLPGAVDVDECSEGTDDCHIDAICQNTPKSYKCLCKPGYKGEGRQCEDIDECENDYYNGGCVHDCINIPGNYRCTCFDGFMLAHDGHNCLDVDECQDNNGGCQQICVNAMGSYECQCHSGFFLSDNQHTCIHRSNEGMNCMNKDHGCAHICRETPKGGVACDCRPGFDLAQNQKDCTLTCNYGNGGCQHSCEDTDTGPMCGCHQKYALHADGRTCIEKDEAAIERSQFNATSVADVDKRVKRRLLMETCAVNNGGCDRTCKDTATGVRCSCPVGFTLQPDGKTCKDINECLMNNGGCDHFCRNTVGSFECGCQKGHKLLTDERTCQDIDECSFERTCDHICINSPGSFQCLCRRGYTLYGTTHCGDVDECSMNNGSCEQGCVNTKGSYECVCPPGRRLHWNQKDCVEMNGCLSRSKASAQAQLSCGKVGGVENCFLSCLGHSLFMPDSESSYILSCGVPGLQGKTLPKRNGTSSSTG--PGCSDAPTTPIRQKARFKIRDAKCHLQPRSQERAKDTLRH-------PLLDNCHVTFVTLKCDSSKKRRRGRKSPSKEVSHITAEFEVEMKVDEASGTCEADCMRKRAEQSLQAAIKILRKSIGRNQFYVQVLGTEYEVAQRPAK-ALEGTGTCGIGQILQDGKCVPCAPGTYFSGDPGQCMPCVSGTYQDMEGQLSCTPCPSSEGLGLAGARNVSECGGQCSPGYFSADGFKPCQACPVGTYQPEPGRTGCFPCGGGLLTKHTGTASFQDCEAKVHCSPGHHYNTTTHRCIRCPVGTYQPEFGQNHCISCPGNTSTDFDGSTNVTHCKNQHCGGELGDYTGYIESPNYPGDYPANAECVWHIAPPPKRRILIVVPEIFLPIEDECGDVLVMRKSASPTSVTTYETCQTYERPIAFTSRSRKLWIQFKSNEANSGKGFQVPYVTYDEDYQQLIEDIVRDGRLYASENHQEILKDKKLIKALFDVLAHPQNYFKYTAQESKEMFPRSFIKLLRSKVSRFLRPYK", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8IWY4-1", "uniprot_id": "SCUB1_HUMAN", "id": "Q8IWY4-1", "name": "Signal peptide, CUB and EGF-like domain-containing protein 1", "aln": "MGAAAVRWHLCVLLALGTRGRLAGGSGLPGSVDVDECSEGTDDCHIDAICQNTPKSYKCLCKPGYKGEGKQCEDIDECENDYYNGGCVHECINIPGNYRCTCFDGFMLAHDGHNCLDVDECQDNNGGCQQICVNAMGSYECQCHSGFFLSDNQHTCIHRSNEGMNCMNKDHGCAHICRETPKGGVACDCRPGFDLAQNQKDCTLTCNYGNGGCQHSCEDTDTGPTCGCHQKYALHSDGRTCIE------------------------------TCAVNNGGCDRTCKDTATGVRCSCPVGFTLQPDGKTCKDINECLVNNGGCDHFCRNTVGSFECGCRKGYKLLTDERTCQDIDECSFERTCDHICINSPGSFQCLCHRGYILYGTTHCGDVDECSMSNGSCDQGCVNTKGSYECVCPPGRRLHWNGKDCVETGKCLSRAKTSPRAQLSCSKAGGVESCFLSCPAHTLFVPDSENSYVLSCGVPGPQGKALQKRNGTSSGLG--PSCSDAPTTPIKQKARFKIRDAKCHLRPHSQARAKETARQ-------PLLDHCHVTFVTLKCDSSKKRRRGRKSPSKEVSHITAEFEIETKMEEASDTCEADCLRKRAEQSLQAAIKTLRKSIGRQQFYVQVSGTEYEVAQRPAK-ALEGQGACGAGQVLQDSKCVACGPGTHFGGELGQCVSCMPGTYQDMEGQLSCTPCPSSDGLGLPGARNVSECGGQCSPGFFSADGFKPCQACPVGTYQPEPGRTGCFPCGGGLLTKHEGTTSFQDCEAKVHCSPGHHYNTTTHRCIRCPVGTYQPEFGQNHCITCPGNTSTDFDGSTNVTHCKNQHCGGELGDYTGYIESPNYPGDYPANAECVWHIAPPPKRRILIVVPEIFLPIEDECGDVLVMRKSASPTSITTYETCQTYERPIAFTSRSRKLWIQFKSNEGNSGKGFQVPYVTYDEDYQQLIEDIVRDGRLYASENHQEILKDKKLIKALFDVLAHPQNYFKYTAQESKEMFPRSFIKLLRSKVSRFLRPYK", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1PAA2-1", "uniprot_id": "A0A8M1PAA2_DANRE", "id": "A0A8M1PAA2-1", "name": "Signal peptide, CUB and EGF-like domain-containing protein 1", "aln": "MGPACFSWEVCLLFLLINTLDVMGNVGVP---DADECSEATDDCHIDALCQNTPKSFKCICKTGYKGDGKHCEDIDECEND-YNGGCVHDCINIPGNYRCTCYDGFMLADDGHNCLDVDECLDNNGGCQQICVNTMGSYECQCKDGFFLSDNQHTCIHRSDDGMNCMNKDHGCAHICREITKGGVACECRPGFELAENQRDCKLTCNYGNGGCQHTCDDTDVGPICGCHQKYALHSDSKTCIEKDEAAIESSEFNTTSVADVDKRVKRRLLMETCAVNNGGCDRTCKDTATGVRCSCPVGFTLQPDGKTCKDIDECLENNGGCDHFCRNTVGSFECSCQKGHKLLTNERTCQDIDECSFERTCDHVCINYPGSFECVCHKGYSLYGFTHCGDIDECSINNGSCEHGCVNTPGSYECVCPPGQKLHWNKKDCVEAVKCLQNGKPPPRAQLSCTKTGGGEVCSLSCPSNALFLADSENSYTLSCGVPVQPGKAPLKRNITTSSSSSLQTCTEMLAQPVKQKARFKIKDAKCHMRPRNKEKHRDMGKQGLQAGQFPCTDDCQVTFVNLKCDSSKKRRRGRKSPSKEVSHITAEFEMEMKEEEASESCNLDCVREKTKQRLQNAMRTLRKSISKQQFYIQFSGTAYEVAQHALRHTTEGDETCSIGQVFTDGKCVSCVVGTFYSGEQEQCVMCPLGTYQDREGQLSCEPCPRTEGQGIAGAKNVSECGGQCPAGQFSSDGFRPCQPCQLGTFQPEPGRVLCFPCGGGLMTKHTGSTSFRDCEAKVHCALGHYYNATTHRCIRCPAGTYQSESGQNYCITCPGNTTTDFDGANNVSHCKNQICGGELGDFMGYIESPNYPGDYPSNVDCVWTINPPNKRRILIVVPEIFLPIEDECGDVLVMRKSALPTSITTYETCQTYERPIAFTSRSRKLWIQFKSNEGNSGKGFQVPYVTYDEDYQQLIEDIVRDGRLYASENHQEILKDKKLIKALFDVLAHPQNYFKYTVQESKEMFPRSFIKLLRSKVSRFLRPYK", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "**.*.. *.: :*: * : *. *:* *.*****.********:*******:**:**.****:*::********** *******:************:******.*********** ************:********:.***************::***************** .******:*****:**:**:**.************:*:***.** **********:*.:**** ****************************************:*** ******************.*:**:****:******************:*** ****:*:*::** *** *****:****:.****::***** **********::**** ***** **...*...:***** *.** * * *** .::**:.***.** ****** **: *** *:*. . *:: : *::*******:*****::*:.: : :: :: * *.*:****.****************************:* * :*** :*: **:*::::* ** *:: *****.::***:*. ** *****:. : : ** :*. **:: *.***.* **.:..: **: * ***** ****** *** ::* *:.**:*********..* ** ***:***.* :**:******. ********:**: *::**::*******: **:**:*********.****.* ***:**:*****:*****:.**:***** *******: *************:*.:*** * ** ***************************** ***:******************************.***************************************************************.***************************", "identical_positions": 738, "similar_positions": 161, "identity": "71.79%" }, { "cls_id": "homologset.agr.MGI:1890618", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D4AEC6-1", "uniprot_id": "D4AEC6_RAT", "id": "D4AEC6-1", "name": "Zinc finger protein 319", "aln": "MSESWQQPPQTQPQQPQAPQPQHHAEPPPALAEHTLPPGTAENPLGCAVYGILLQPDPGLQP-------------------------PQHAPLQAG-EPGPKCGVCGHDLAHLSSPHEHQCLAGHDRSFQCTQCLKIFHQATDLLEHQCVQAEQKPFVCGVCKMGFSLLTSLAQHHSSHTG--MVKCSICDKTYKP--AEAAEPATTTAPSLPSAPPPTNVAPVEQ------------PEKPYSCPICQKPFKHLSELSRHERIHTGEKPYKCTLCDKSFSQSSHLVHHKRTHSSERPYKCAVCEKTFKHRSHLVRHMYAHSGEHHLFRCNVCELHFKESSELLQHPCTPSGERPFRCGECQKAFKRPSDLRQHERTHSAERPFKCDLCPMGFKQQYALMRHRRTHK--TEEPFKCGLCEKGFGQPSHLLYHQHVHTLETLFKCPVCQKGFDQSAELLRHKC-----LPGSTERPFKCPVCNKAYKRASALQKHQLSHCAAAEKPLRCTLCERRFFSSSEFVQHRCDPTREKPLKCPDCEKRFKYASDLQRHRRVHTGEKPYKCPNCDKAFKQREHLNKHQGVHAREQQFKCVWCGERFLDVALLQEHSAQHSAAAAAAEGAYQVAACLP", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9ERR8-1", "uniprot_id": "ZN319_MOUSE", "id": "Q9ERR8-1", "name": "Zinc finger protein 319", "aln": "MSESWQQPPQTQPQQPQAPQPQHHAETPPALAEHTLPPGSAENPLGCAVYGILLQPDPGLQP-------------------------PQHAPLQAG-EPGPKCGVCGHDLAHLSSPHEHQCLAGHDRSFQCTQCLKIFHQATDLLEHQCVQAEQKPFVCGVCKMGFSLLTSLAQHHSSHTG--MVKCSICDKTYKP--AEAAEPATTTAPSLPSAPPPANIAPVEQ------------PEKPYSCPVCQKPFKHLSELSRHERIHTGEKPYKCTLCDKSFSQSSHLVHHKRTHSSERPYKCAVCEKTFKHRSHLVRHMYAHSGEHHLFRCNVCELHFKESSELLQHPCTPSGERPFRCGECQKAFKRPSDLRQHERTHSAERPFKCDLCPMGFKQQYALMRHRRTHK--TEEPFKCGLCEKGFGQPSHLLYHQHVHTLETLFKCPVCQKGFDQSAELLRHKC-----LPTSTERPFKCPVCNKAYKRASALQKHQLSHCAAAEKPLRCTLCERRFFSSSEFVQHRCDPAREKPLKCPDCEKRFKYASDLQRHRRVHTGEKPYKCPSCDKAFKQREHLNKHQGVHAREQQFKCVWCGERFLDVALLQEHSAQHSAAAAAAEGAYQVAACLP", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9P2F9-1", "uniprot_id": "ZN319_HUMAN", "id": "Q9P2F9-1", "name": "Zinc finger protein 319", "aln": "MSESWQQPPQTQPQQPQPPQPQHHAEPPPALAEHTLPPGTAENPLGCAVYGILLQPDPGLQP-------------------------PQHAPLQAAGEPGPKCGVCGHDLAHLSSPHEHQCLAGHDRSFQCTQCLKIFHQATDLLEHQCVQAEQKPFVCGVCKMGFSLLTSLAQHHSSHSG--LVKCSICEKTYKP--AEAAEPATTAAPSLPAAPAPSTVTPAEQ------------ADKPYSCPICQKPFKHLSELSRHERIHTGEKPYKCTLCDKSFSQSSHLVHHKRTHSSERPYKCAVCEKTFKHRSHLVRHMYAHSGEHHLFRCNVCELHFKESSELLQHPCTPSGERPFRCGECQKAFKRPSDLRQHERTHSAERPFKCDLCPMGFKQQYALMRHRRTHK--TEEPFKCGLCEKGFGQPSHLLYHQHVHTLETLFKCPVCQKGFDQSAELLRHKC-----LPGAAERPFKCPVCNKAYKRASALQKHQLAHCAAAEKPLRCTLCERRFFSSSEFVQHRCDPAREKPLKCPDCEKRFKYASDLQRHRRVHTGEKPYKCPNCDKAFKQREHLNKHQGVHAREQQFKCVWCGERFLDVALLQEHSAQHSAAAAAAEGAYQVAACLP", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M2BLK1-1", "uniprot_id": "A0A8M2BLK1_DANRE", "id": "A0A8M2BLK1-1", "name": "", "aln": "MTEAWQQ---------------HAVAPPP--VVHTIPPG--ADALGCTVYGIVLQPDTTLQQQQQQQQQQQQHHSQQHNQQQQHPAQSQQPSLHVGNEGGHKCGACGHDISHLANPHEHQCMVSQDRSFQCTQCLKIFHQATDLLEHQCVQVEQKPFVCGVCKMGFSLLTSLAQHHNAHNSGNPMKCSICEKTYRPGSGNATPTSSSATPGQPSNDEASSSGSAAVGTSGQPTFEPSHPDRPYKCSVCTKGFRHLSELTRHERVHTGEKPFKCETCDKSFSQSSHLAHHQRTHSSERPFKCAVCEKSFKHRSHLVRHMYAHSGEH-LFKCNLCELHFKESSELLHHQCQPQGARPFRCATCGKGFKRPSDLRQHERTHSEERPFHCEDCQMSFKQQYALVRHRRTHKPSADRPFKCNLCDKGFLQPSHLLYHQHVHGMDNLFKCASCGKGFSQSGELLRHKCGESSSTPTNPDKPYKCDVCGKAYKKATTLQRHQNSHCT--EKPLKCSLCDRRFLSSSEFVQHRCDPSREKPLKCPDCEKRFKYSSEMQRHRRVHTGEKPYKCASCDKGFKQREHLAKHQSVHARDAQFKCVWCGERFADLGALQEHTVQHTAEG----GGYPVSSLIQ", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*:*:*** * . .** . **:*** :.***:****:****. ** .*:..*:.. * * ***.****::**:.******:..:**************************.************************.:*.. :*****:***:* .:*: .:::::*. *: .:. .. .::**.*.:* * *:*****:****:******:** ***********.**:********:*******:****************** **:**:************:* * *.* *****. * *.*************** ****:*: * *.*******:******* ::.****.**:*** ************ ::.****. * ***.**.******* * .::*:** **.****:*::**:** :**: ****:*:**:***:************:****************:*::***************..***.******* ***.****: *********** *:. ****:.**:* . *.* *:: : ", "identical_positions": 388, "similar_positions": 120, "identity": "61.59%" }, { "cls_id": "homologset.agr.MGI:1890619", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0ABK0LN48-1", "uniprot_id": "A0ABK0LN48_RAT", "id": "A0ABK0LN48-1", "name": "Gigaxonin", "aln": "MAEGSAVSDPQHAARLLRALSSFREEARFCDAHLVLDGEEIPVQKNILAAASPYIRTKLNYNPPKDDGSTYKIELEGISVTIMREILDYIFSGQIRLNEDTIQDVVQAADLLLLTDLKTLCCEFLEGCIAAENCIGIRDFALHYCLHHVHYLATEYLETHFRDVSSTEEFLELSPQKLKEVISLEKLNVGNERYVFEAVIRWIAHDVEMRKVHMKDVMSALWVSGLDSSYLREQMLNEPLVREIVKECSNIPLSQPQQGEAMLASFKPRGYSECIVTIGGEERVSRKPTAAMRCMCPLYDPNRQLWIELAPLSMPRINHGVLSAEGFLFVLGGQDENKQTLSSGEKYDPDANTWTALPPMNEARHNFGIVEIDGMLYILGGEDGDRELISMECYDIYSKTWTKQPDLTMVRKIGCYAAMKKKIYAMGGGSYGKLFESVECYDPRTQQWTAICPLKERRFGAVACGVAMELYVFGGVRSREDIQGSEMVTCKSEFYHDEFKRWIYLNDQNLCIPASSSFVYGAVPIGASIYVIGDLDTGTNYDYVREFKRSTGTWHHTKPLLPSDLRRTGCAALRIANCKLFRLQLQQGLFRIRVHSP", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8CA72-1", "uniprot_id": "GAN_MOUSE", "id": "Q8CA72-1", "name": "Gigaxonin", "aln": "MAEGSAVSDPQHAARLLRALSSFREEARFCDAHLVLDGEEIPVQKNILAAASPYIRTKLNYNPPKDDGSTYKIELEGISVMVMREILDYIFSGQIRLNEDTIQDVVQAADLLLLTDLKTLCCEFLEGCIAAENCIGIRDFALHYCLHHVHYLATEYLETHFRDVSSTEEFLELSPQKLKEVISLEKLNVGNERYVFEAVIRWIAHDVEMRKVHMKDVMSALWVSGLDSSYLREQMLNEPLVREIVKECSNIPLSQPQQGEAMLASFKPRGYSECIVTIGGEERVSRKPTAAMRCMCPLYDPNRQLWIELAPLSMPRINHGVLSAEGFLFVLGGQDENKQTLSSGEKYDPDANTWTALPPMHEARHNFGIVEIDGMLYILGGEDGDRELISMECYDIYSKTWTKQPDLTMVRKIGCYAAMKKKIYAMGGGSYGKLFESVECYDPRTQQWTAICPLKERRFGAVACGVAMELYVFGGVRSREDIQGSEMVTCKSEFYHDEFKRWIYLNDQNLCIPASSSFVYGAVPIGASIYVIGDLDTGTNYDYVREFKRSTGTWHHTKPLLPSDLRRTGCAALRIANCKLFRLQLQQGLFRIRVHSP", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9H2C0-1", "uniprot_id": "GAN_HUMAN", "id": "Q9H2C0-1", "name": "Gigaxonin", "aln": "MAEGSAVSDPQHAARLLRALSSFREESRFCDAHLVLDGEEIPVQKNILAAASPYIRTKLNYNPPKDDGSTYKIELEGISVMVMREILDYIFSGQIRLNEDTIQDVVQAADLLLLTDLKTLCCEFLEGCIAAENCIGIRDFALHYCLHHVHYLATEYLETHFRDVSSTEEFLELSPQKLKEVISLEKLNVGNERYVFEAVIRWIAHDTEIRKVHMKDVMSALWVSGLDSSYLREQMLNEPLVREIVKECSNIPLSQPQQGEAMLANFKPRGYSECIVTVGGEERVSRKPTAAMRCMCPLYDPNRQLWIELAPLSMPRINHGVLSAEGFLFVFGGQDENKQTLSSGEKYDPDANTWTALPPMNEARHNFGIVEIDGMLYILGGEDGEKELISMECYDIYSKTWTKQPDLTMVRKIGCYAAMKKKIYAMGGGSYGKLFESVECYDPRTQQWTAICPLKERRFGAVACGVAMELYVFGGVRSREDAQGSEMVTCKSEFYHDEFKRWIYLNDQNLCIPASSSFVYGAVPIGASIYVIGDLDTGTNYDYVREFKRSTGTWHHTKPLLPSDLRRTGCAALRIANCKLFRLQLQQGLFRIRVHSP", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "**************************:***************************************************** :****************************************************************************************************************************.*:*******************************************************.************:****************************************************:*****************************:***********************::*********************************************************************************************** *******************************************************************************************************************", "identical_positions": 585, "similar_positions": 10, "identity": "97.99%" }, { "cls_id": "homologset.agr.MGI:1890621", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "E9PSU2-1", "uniprot_id": "E9PSU2_RAT", "id": "E9PSU2-1", "name": "", "aln": "MAVSVPGYSPSFKRPPEVVRLRRKRPRDHGTAVS--SALPEPALRRAALAAGLPLRPFPTAGGRGG---ATTTIARRNPFARLDNRPRVADEAPEEPLRGPQGAPGPLLDSNGENNLLWEEAS-HERTVTELSQSQQVTLSESDTWSSDGTELPVDWSIKTRLLFTSSQPFSWAEHLKAQEEAQGLVQHCRATEVTLPQSIPDPKLSTVLRCAFQQTLVYWLHPAFSWLPLFPRIGADRKMAAKTSPWSTDESLQHALMSDWSVSFTSLYNLLKTKLCPYFYVCSYQFTVLFRAAGLAGSSVITALITPTTRGLREAMKSEGIEFSLPLLEESG---------HKEKVRE-PSLESEEEQAVSDEDEEESLSWLEEIGVQDQIKKPDLISVKLRKEKHEVQMDHRPESVVLVKGLNTFKLLNFLINCKSLVATSGAQAGLPPTLLSPVAFRGASMQMLKARSINVKTQALFGYRDKFSLEITGPVMPHALHSVAMLLRSS-------QRGSFSAGLYAHEPTAVFNVGLPLDKELDRKGAH------KDLANCGLHPKTLEQLSQMPVLGKSSLRNVEMS-DYIVNWRS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9QXP4-1", "uniprot_id": "DONS_MOUSE", "id": "Q9QXP4-1", "name": "Protein downstream neighbor of Son", "aln": "MAVSVPGYSPSFKRPPETVRLRRKRSRDHGAAVP--ASLPEPAPRRAALAAGLPLRPFPTAGGRGG---AAATIARRNPFARLDNRPRVSDEASEEPLRGPQGASGPLLDSNEENNLLWEDTSSHERTGTELSQSQRVSLSESDTWSSDGTELPVDWSIKTRLLFTSSQPFSWADHLKAQEEAQGLVQHCRATEVTLPQSIQDPKLSTALRCAFQQALVYWLHPAFSWLPLFPRIGADRKMAAKTSPWSADETLQHALMSDWSVSFTSLYNLLKTKLCPYFYVCSYQFTVLFRAAGLAGSSVITALISPTTRGLREAMRNEGIEFSLPLLEEIG---------HKKKVRD-PSLESEEEQAVSDEDEEESFSWLEEIGVQDQIKKPDVISIKLRKEKHEVQMDHRPESVVLVKGLNTFKLLNFLINCKSLVATSGAQAGLPPTLLSPIAFRGASMQMLKARSSNVKTQALSGYRDKFSLDITGPVMPHALHSMSMLLRSS-------QRGSFSAGLYAHEPTAVFNVGLSLDKELDRKVAR------EDLANCGLHPKTLEQLSQRPVLGKSSLRSVEMS-DYILSWRS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9NYP3-1", "uniprot_id": "DONS_HUMAN", "id": "Q9NYP3-1", "name": "Protein downstream neighbor of Son", "aln": "MALSVPGYSPGFRKPPEVVRLRRKRARSRGAAASPPRELTEPAARRAALVAGLPLRPFPAAGGRGGGSGGGPAAARRNPFARLDNRPRVAAEPPDGPAREQPEAPVPFLDSNQENDLLWEEKFPERTTVTELPQTSHVSFSEPDIPSSKSTELPVDWSIKTRLLFTSSQPFTWADHLKAQEEAQGLVQHCRATEVTLPKSIQDPKLSSELRCTFQQSLIYWLHPALSWLPLFPRIGADRKMAGKTSPWSNDATLQHVLMSDWSVSFTSLYNLLKTKLCPYFYVCTYQFTVLFRAAGLAGSDLITALISPTTRGLREAMRNEGIEFSLPLIKESG---------HKKETASGTSLGYGEEQAISDEDEEESFSWLEEMGVQDKIKKPDILSIKLRKEKHEVQMDHRPESVVLVKGINTFTLLNFLINSKSLVATSGPQAGLPPTLLSPVAFRGATMQMLKARSVNVKTQALSGYRDQFSLEITGPIMPHSLHSLTMLLKSS-------QSGSFSAVLYPHEPTAVFNICLQMDKVLDMEVVH------KELTNCGLHPNTLEQLSQIPLLGKSSLRNVVLR-DYIYNWRS", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VNA8-1", "uniprot_id": "DONS_DROME", "id": "Q9VNA8-1", "name": "Protein downstream neighbor of son homolog", "aln": "-MSTEASVASKWTRPDDFIKLQRLKQKKNKLAARVSNNNNRRPRHQVDETDKSKLLEAKLAQKRKNPFAKSTADAKKLRVDPQLADLEPVVTASSCFVRETPTRPAPAKFVLQKYDPQAFAKLFQHPQINAEDEDD----AELAARQKHTAHLPVDWSLKTRARFFCPTELP-AIQLKTSQLASGLTSFVRCMDPQRTEST----LDISDATRFNQCNYYWQHPHLPWLTLYPRT------AKENVGVVVGERERKALAEEWDFSFRGLFQLLRARQCPYFYLCANTFTVLFRAAGVGGRPESHALVTPSTRGMRQALRQEGIEFSMPLKSDNSGNAHDNSFNEESTTTSLGPEAGEDAPPPAQEDEDDDEDWLESLGVDERELRRIQSSHARKQQAAEMREDFSDNSLLLVDGVECQGFFSYLLNAKSAISTVGRLAGVPPTLLSPVAFPKATMQHLVPRSKKVRLDGVD----YFSIDIKGLILPTFLPSVAELLSETRQMFSSTLASSINTLAFSKATQKLLETPETPQSDAEGEDAAGQVFGEQNLSECGLLPAVVGSICRTGQHAVGLLERVCYQRDEGYAWS-", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : .. :. : :* : ::*:* : :.. *. . . ::. . * * * . .: *:: . . ... * . * : : .. . : . :* ... :.******:*** * .. :. * :**:.: *.**... *. : .:* *. *:* ** ** :.**.*:** * :. . ::.* .:*..** .*::**::: *****:*: *********:.* **::*:***:*:*::.******:** .: . .:. . . . : . ::***::. .***.:**::: : * ::: *:: *. :*::**.*:: ::.:*:*.** ::* * **:*******:** *:** * .** :*: :.: **::*.* ::* * *:: ** .: .*:.: :.: . ::: :. : : . ::*::*** * .: .:.: . . *. * * * ", "identical_positions": 139, "similar_positions": 188, "identity": "23.6%" }, { "cls_id": "homologset.agr.MGI:1890645", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZBE5-1", "uniprot_id": "NEK7_RAT", "id": "D3ZBE5-1", "name": "Serine/threonine-protein kinase Nek7", "aln": "MDEQPQGMQGPPVPQFQPQKALRPDMGYNTLANFRIEKKIGRGQFSEVYRASCLLDGVPVALKKVQIFDLMDAKARADCIKEIDLLKQLNHPNVIKYYASFIEDNELNIVLELADAGDLSRMIKHFKKQKRLIPERTVWKYFVQLCSALDHMHSRRVMHRDIKPANVFITATGVVKLGDLGLGRFFSSKTTAAHSLVGTPYYMSPERIHENGYNFKSDIWSLGCLLYEMAALQSPFYGDKMNLYSLCKKIEQCDYPPLPSDHYSEELRQLVNICINPDPEKRPDIAYVYDVAKRMHACTASS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9ES74-1", "uniprot_id": "NEK7_MOUSE", "id": "Q9ES74-1", "name": "Serine/threonine-protein kinase Nek7", "aln": "MDEQSQGMQGPPVTQFQPQKALRPDMGYNTLANFRIEKKIGRGQFSEVYRASCLLDGVPVALKKVQIFDLMDAKARADCIKEIDLLKQLNHPNVIKYYASFIEDNELNIVLELADAGDLSRMIKHFKKQKRLIPERTVWKYFVQLCSALDHMHSRRVMHRDIKPANVFITATGVVKLGDLGLGRFFSSKTTAAHSLVGTPYYMSPERIHENGYNFKSDIWSLGCLLYEMAALQSPFYGDKMNLYSLCKKIEQCDYPPLPSDHYSEELRQLVNICINPDPEKRPDIAYVYDVAKRMHACTAST", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8TDX7-1", "uniprot_id": "NEK7_HUMAN", "id": "Q8TDX7-1", "name": "Serine/threonine-protein kinase Nek7", "aln": "MDEQSQGMQGPPVPQFQPQKALRPDMGYNTLANFRIEKKIGRGQFSEVYRAACLLDGVPVALKKVQIFDLMDAKARADCIKEIDLLKQLNHPNVIKYYASFIEDNELNIVLELADAGDLSRMIKHFKKQKRLIPERTVWKYFVQLCSALEHMHSRRVMHRDIKPANVFITATGVVKLGDLGLGRFFSSKTTAAHSLVGTPYYMSPERIHENGYNFKSDIWSLGCLLYEMAALQSPFYGDKMNLYSLCKKIEQCDYPPLPSDHYSEELRQLVNMCINPDPEKRPDVTYVYDVAKRMHACTASS", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6DEH7-1", "uniprot_id": "Q6DEH7_DANRE", "id": "Q6DEH7-1", "name": "NEK6-subfamily protein kinase", "aln": "MDAQSQGQQ-PPVPVYQPQ---KIDMGYNSLANFAIEKKIGRGQFSEVYRATYVLDHTIVALKKIQIFDLMDAKARQDCIKEIDLLKQLNHPNVIKYHASFIEENELNIVLELADAGDLSQMIRHFKKQRRLIPEKTVWKYFVQLCSALEHMHSRRIMHRDIKPANVFITATGVVKLGDLGLGRFFSSKTTAAHSLVGTPYYMSPERIHENGYNFKSDIWSLGCLLYEMAALQSPFYGDKMNLYSLCKKIEQCDYPPLPSDHYSQELRKLVDMCINPDPEKRPDITYVYSMAKHMHGRIAN-", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "** *.** * ***. :*** : *****:**** ****************: :** . *****:*********** ********************:*****:****************:**:*****:*****:*************:******:***********************************************************************************************************:***:**::***********::***.:**:**. *. ", "identical_positions": 258, "similar_positions": 28, "identity": "85.43%" }, { "cls_id": "homologset.agr.MGI:1890646", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZGQ5-1", "uniprot_id": "NEK8_RAT", "id": "D3ZGQ5-1", "name": "Serine/threonine-protein kinase Nek8", "aln": "-----------------------------------------------------------------------------------------------------MEKYERIRVVGRGAFGIVHLCLRKADQKLVIIKQIPVEQMTKEERQAAQNECQVLKLLNHPNVIEYYENFLEDKALMIAMEYAPGGTLAEFIQKRCN-SLLEEETILHFFVQILLALHHVHTHLILHRDLKTQNILLDKHRMVVKIGDFGISKILSSKSKAYTVVGTPCYISPELCEGKPYNQKSDIWALGCVLYELASLKRAFEAANLPALVLKIMSGTFAPISDRYSPELRQLVLSLLSLEPAQRPPLSHIMA--QPLCIRALLN--IHTDVGSVRMRRAEKCLTPGTPMAPGSTGSRATSARCRG--VPRGPVRPAIPPPLSS-------VYAWGGGLSIPLRLPMPNTEVVQVAAGRTQKAGVTRSGRLILWEAPPLGTGGGTLLPGAVELPQPQFVSRFLEGQSGVTIKHVACGDLFTACLTDRGIIMTFGSGSNGCLGHGSLTDISQPTIVEALLGYEMVQVACGASHVLALSADGELFAWGRGDGGRLGLG-TRESHNCPQQVPMVPGQE-AQRVVCGIDCSMILTSPGRVLACGSNRFNKLGLDCLSLEEEPVPHQQVEEALSFTPLGSAPLDRETLLCVDLGTAHSAAVTASGACYTFGSNQHGQLGTSSRRVSRAPCRVQGLEGIKMVMVACGDAFTVAIGAEGEVYSWGKG---------------------ARGRLGR-----------------------------RDEDAGLPRPVQLDETHPYTVTSVSCCHGNTLLAVRSVTDEPVPP", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q91ZR4-1", "uniprot_id": "NEK8_MOUSE", "id": "Q91ZR4-1", "name": "Serine/threonine-protein kinase Nek8", "aln": "-----------------------------------------------------------------------------------------------------MEKYERIRVVGRGAFGIVHLCLRKADQKLVILKQIPVEQMTKEERQAAQNECQVLKLLNHPNVIEYYENFLEDKALMIAMEYAPGGTLAEFIQKRCN-SLLEEETILHFFVQILLALHHVHTHLILHRDLKTQNILLDKHRMVVKIGDFGISKILSSKSKAYTVVGTPCYISPELCEGKPYNQKSDIWALGCVLYELASLKRAFEAANLPALVLKIMSGTFAPISDRYSPELRQLVLSLLSLEPAQRPPLSHIMA--QPLCIRALLN--IHTDVGSVRMRRAEKSLTPGPPIASGSTGSRATSARCRG--VPRGPVRPAIPPPLSS-------VYAWGGGLSSPLRLPMLNTEVVQVAAGRTQKAGVTRSGRLILWEAPPLGAGGGTLLPGAVELPQPQFVSRFLEGQSGVTIKHVACGDLFTACLTDRGIIMTFGSGSNGCLGHGNLTDISQPTIVEALLGYEMVQVACGASHVLALSTDGELFAWGRGDGGRLGLG-TRESHNCPQQVPVAPGQE-AQRVVCGIDSSMILTSPGRVLACGSNRFNKLGLDHLSLDEEPVPYQQVEEALSFTPLGSAPLDQEPLLCVDLGTAHSAAITASGDCYTFGSNQHGQLGTSSRRVSRAPCRVQGLEGIKMVMVACGDAFTVAVGAEGEVYSWGKG---------------------TRGRLGR-----------------------------RDEDAGLPRPVQLDETHPYMVTSVSCCHGNTLLAVRSVTDEPVPP", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q86SG6-1", "uniprot_id": "NEK8_HUMAN", "id": "Q86SG6-1", "name": "Serine/threonine-protein kinase Nek8", "aln": "-----------------------------------------------------------------------------------------------------MEKYERIRVVGRGAFGIVHLCLRKADQKLVIIKQIPVEQMTKEERQAAQNECQVLKLLNHPNVIEYYENFLEDKALMIAMEYAPGGTLAEFIQKRCN-SLLEEETILHFFVQILLALHHVHTHLILHRDLKTQNILLDKHRMVVKIGDFGISKILSSKSKAYTVVGTPCYISPELCEGKPYNQKSDIWALGCVLYELASLKRAFEAANLPALVLKIMSGTFAPISDRYSPELRQLVLSLLSLEPAQRPPLSHIMA--QPLCIRALLN--LHTDVGSVRMRRAEKSVAP------SNTGSRTTSVRCRG--IPRGPVRPAIPPPLSS-------VYAWGGGLGTPLRLPMLNTEVVQVAAGRTQKAGVTRSGRLILWEAPPLGAGGGSLLPGAVEQPQPQFISRFLEGQSGVTIKHVACGDFFTACLTDRGIIMTFGSGSNGCLGHGSLTDISQPTIVEALLGYEMVQVACGASHVLALSTERELFAWGRGDSGRLGLG-TRESHSCPQQVPMPPGQE-AQRVVCGIDSSMILTVPGQALACGSNRFNKLGLDHLSLGEEPVPHQQVEEALSFTLLGSAPLDQEPLLSIDLGTAHSAAVTASGDCYTFGSNQHGQLGTNTRRGSRAPCKVQGLEGIKMAMVACGDAFTVAIGAESEVYSWGKG---------------------ARGRLGR-----------------------------RDEDAGLPRPVQLDETHPYTVTSVSCCHGNTLLAVRSVTDEPVPP", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q90XC2-1", "uniprot_id": "NEK8_DANRE", "id": "Q90XC2-1", "name": "Serine/threonine-protein kinase Nek8", "aln": "-----------------------------------------------------------------------------------------------------MEKYEKTKVVGRGAFGIVHLCRRRTDSALVILKEIPVEQMTRDERLAAQNECQVLKLLSHPNIIEYYENFLEDKALMIAMEYAPGGTLADYIQKRCN-SLLDEDTILHSFVQILLALYHVHNKLILHRDLKTQNILLDKHQMIVKIGDFGISKILVSKSKAYTVVGTPCYISPELCEGKPYNQKSDIWALGCVLYELASLKRAFEAANLPALVLKIMSGTFAPISDRYSPELRQLILNMLNLDPSKRPQLNEIMA--HAICIRPLLN--LYTDIGNVKMRRIEKPLSNVQAGPHGRPGGWITSTRTRGGLSSLTSSKMMHPLPLFS-------VYTWGSGISTPLRLPMLNTEVIQVSLGRTQKMGVTKSGRLITWEAPSVGSGE-PTLPGAVEQMQPQFISRFLEGQSGVTIKSVSCGDLFTTCLTDRGIIMTFGSGSNGCLGHGNFNDVTQPKIVEALLGYELVQVSCGASHVLAVTNEREVFSWGRGDNGRLGLA-TQDSHNCPQQVSLPADFE-AQRVLCGVDCSMIMSTQHQILACGNNRFNKLGLDKVSGTEEPSSFCQVEEVHLFQLVQSAPLNTEKIVYIDIGTAHSVAVTEKGQCFTFGSNQHGQLGCSHRRSSRVPYQVSGLQGIT--MAACGDAFTLAIGAEGEVYTWGKG---------------------ARGRLGR-----------------------------KEEDFGIPKPVQLDESHAFTVTSVACCHGNTLLAVKPFFEEPGPK", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VC32-1", "uniprot_id": "Q9VC32_DROME", "id": "Q9VC32-1", "name": "", "aln": "MKKFRAKASSLPIFNGRITDATTLTTSSLQLPLGQNTQRKQSTCTRVLPTVFTITDGTTGAASTSLAEAMSSSKAQMPNRQESLLQLSVPRETGVGVAGPELANYEKVRVVGQGSFGIAILYRRKSDGHQIVFKQINLSELSPPGRDLAMNEVDVFSKLHHPNIVSYLGSFIKDNTLLIEMEYADGGTLAQIIAERQGKLHFPERYIIAVFEQISSAINYMHSENILHRDLKTANVFLNR-RGIVKIGDFGISKIMNTKIHAQTVLGTPYYFSPEMCEGKEYDNKSDIWALGCILGEMCCLKKTFAASNLSELVTKIMAGNYTPVPSGYTSGLRSLMSNLLQVEAPRRPTASEVLVYWIPLIFRSLGKNKGYSYEDDVGGPGSDQLTAPVPAAAYSNVSMELELPTAQTETKQLMIADTAAPHEILEKRSVLYQLKAFGTCFSMAPIQLPPKAVIVDVAMSDSHFVVVNEDGSAYAWGEGTHGQLGLTALEAWKHYPSR------MESVRNYHVVSACAGDGFTILVTQAGSLLSCGSNAHLALGQDEQRNYHSPKLIARLADVRVEQVAAGLQHVLALSREGAVYVWGTSTCGALGLGNYQQQQKFPQKILLSHVKTKPSKIYCGPDTSAVLFANGELHVCGSNDYNKLG------------FQRSAKITAFKKVQLP----HKVTQACFSSTHSVFLVEGGYVYTMGRNAEGQRGIRHCNSVDHPTLVDSVKSRYIVKANCSDQCTIVASEDNIITVWGTRNGLPGIGSTNCGLGLQICTPNMELELGNNTAAFTNFLASVYKSELILEPVDILALFSSKEQCDRGYYVQVHDVYPLAHSVLVLVDTTTPLISSYEGDYPHL-", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : :**: :***:*:***. * *::* :::*:* :.::: * * ** :*:. * ***::.* .*::*::*:* **** *****: * :* . : * *: * ** *: ::*.. ******** *::*:: : :***********: :* :* **:*** *:***:**** *::*********:* *:..**::* *:**. ** ***:*.::*:.. *:. **.*: .:*.::..:** ..::. .: :*.* : :: ..* :: : . . : * : . : ::* :. . :: :::*: . :: *...* * . * . * . . . :*. . : ...** ** :*: * ::: **.:: .**:.. : .*.:: * . .: **:.* .****:: : :: ** . * ***. ::.:. **:: : ..:: ** * * :: . .**.* :**** . : : * : . . : :.::**. :. * :*:* * .** * . * *..::. . *.* *:. . :. : **. . .**. .*: . **:.: :. : : . .* * : * ", "identical_positions": 189, "similar_positions": 229, "identity": "21.85%" }, { "cls_id": "homologset.agr.MGI:1890647", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZYS4-1", "uniprot_id": "D3ZYS4_RAT", "id": "D3ZYS4-1", "name": "Fidgetin", "aln": "-----------MQWTPEHAQWPEQHFDITSTTRSPAHKVEAYRGHLQRTYQYAWANDDISALTASNLLKKYAEKYSG-------ILEGPVDRPVLSNYSDTPSGLVNGRKNDSEPWQSSLNSEAVYPMNCVPDVITAS-------------------------------------------------------------------------------------------------------------KAGVSSALPPVDVSASIGSSPGVASNLTEPSYSSSTCGSHTVPSLHAGLPSQEYAPGYNGSYLHSTYSS-QPTPALPSPHPSPLHSSGLLQPP-PPPPPPPALVPGYNGTS-NLSSYSYPSASYPPQTAVGSGYSPGGAPPPPSAYLPSGIPAPTPLPPTTVPGYTYQGHGLTPIAPS-ALTNSSASSLKRKAFYMAGQGDMDSSYGNYSYGQQRSTQSPMYRMPDNSISNSNRGNGFDRNAETSSLAFKPTKQLMPSEQQRKFSSQSSRALTPPSYSTAKNSLGS-RSSESFGKYTSPVMSEHGDDHRQLLAHPIQGPGLRAATSSNHSVDEQLKNTDTHLIDLVTNEIITQGPPVDWSDIAGLDLVKAVIKEEVLWPVLRSDAFSGLTALPRSILLFGPRGTGKTLLGRCIASQLGATFFKIAGSGLVAKWLGEAEKIIHASFLVARCRQPSVIFVSDIDMLLSSQVSEEHSPVSR-MRTEFLMQLDTVLTSAE------------------DQIVVICATSKPEEIDESLRRYFMKRLLIPLPDSTARHQIIVQLLSQHNYCLNDKEFALLVQRTEGFSGLDVAHLCQEAAVGPLHAMPATDLSAIMPSQLRPITYQDFENAFCKIQPSISQKELDMYVEWNKMFGCSQ-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9ERZ6-1", "uniprot_id": "FIGN_MOUSE", "id": "Q9ERZ6-1", "name": "Fidgetin", "aln": "MISSTSVYGLKMQWTPEHAQWPEQHFDITSTTRSPAHKVEAYRGHLQRTYQYAWANDDISALTASNLLKKYAEKYSG-------ILEGPVDRPVLSNYSDTPSGLVNGRKNDSEPWQPSLNSEAVYPMNCVPDVITAS-------------------------------------------------------------------------------------------------------------KAGVSSALPPVDVSASIGSSPGVASNLTEPSYSSSTCGSHTVPSLHAGLPSQEYAPGYNGSYLHSTYSS-QATPALPSPHPSPLHSSGLLQPP-PPPPPPPALVPGYNGTS-NLSSYSYPSASYPPQTAVGSGYSPGGAPPPPSAYLPSGIPAPTPLPPTTVPGYTYQGHGLTPIAPS-ALTNNSASSLKRKAFYMAGQGDMDSSYGNYSYGQQRSTQSPMYRMPDNSISNSNRGNGFDRNAETSSLAFKPTKQLMPSEQQRKFSSQSSRALTPPSYSTAKNSLGS-RSSESFGKYTSPVMSEHGDDHRQLLAHPIQGPGLRAATSSNHSVDEQLKNTDTHLIDLVTNEIITQGPPVDWSDIAGLDLVKAVIKEEVLWPVLRSDAFSGLTALPRSILLFGPRGTGKTLLGRCIASQLGATFFKIAGSGLVAKWIGEAEKIIHASFLVARCRQPSVIFVSDIDMLLSSQVSEEHSPVSR-MRTEFLMQLDTVLTSAE------------------DQIVVICATSKPEEIDESLRRYFMKRLLIPLPDSTARHQIIVQLLTQHNYCLNDKEFALLVQRTEGFSGLDVAHLCQEAAVGPLHAMPATDLSAIMPSQLRPVTYQDFENAFCKIQPSISQKELDMYVEWNKMFGCSQ-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q5HY92-1", "uniprot_id": "FIGN_HUMAN", "id": "Q5HY92-1", "name": "Fidgetin", "aln": "MISSTSVYGLKMQWTPEHAQWPEQHFDITSTTRSPAHKVEAYRGHLQRTYQYAWANDDISALTASNLLKKYAEKYSG-------ILEGPVDRPVLSNYSDTPSGLVNGRKNESEPWQPSLNSEAVYPMNCVPDVITAS-------------------------------------------------------------------------------------------------------------KAGVSSALPPADVSASIGSSPGVASNLTEPSYSSSTCGSHTVPSLHAGLPSQEYAPGYNGSYLHSTYSS-QPAPALPSPHPSPLHSSGLLQPP-PPPPPPPALVPGYNGTS-NLSSYSYPSASYPPQTAVGSGYSPGGAPPPPSAYLPSGIPAPTPLPPTTVPGYTYQGHGLTPIAPS-ALTNSSASSLKRKAFYMAGQGDMDSSYGNYSYGQQRSTQSPMYRMPDNSISNTNRGNGFDRSAETSSLAFKPTKQLMSSEQQRKFSSQSSRALTPPSYSTAKNSLGS-RSSESFGKYTSPVMSEHGDEHRQLLSHPMQGPGLRAATSSNHSVDEQLKNTDTHLIDLVTNEIITQGPPVDWNDIAGLDLVKAVIKEEVLWPVLRSDAFSGLTALPRSILLFGPRGTGKTLLGRCIASQLGATFFKIAGSGLVAKWLGEAEKIIHASFLVARCRQPSVIFVSDIDMLLSSQVNEEHSPVSR-MRTEFLMQLDTVLTSAE------------------DQIVVICATSKPEEIDESLRRYFMKRLLIPLPDSTARHQIIVQLLSQHNYCLNDKEFALLVQRTEGFSGLDVAHLCQEAVVGPLHAMPATDLSAIMPSQLRPVTYQDFENAFCKIQPSISQKELDMYVEWNKMFGCSQ-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q503S1-1", "uniprot_id": "FIGN_DANRE", "id": "Q503S1-1", "name": "Fidgetin", "aln": "-----------MQWTPEHAQWAEQHFDISSTTRSLAHKAEAYRGHLQRTYQYAWANDDISALTASNLLKKYAEKYSG-------ILEGPSERALLCSYSESAPGLLNGRKSESDAWQ-----EGIYPMSCAADVISAS-------------------------------------------------------------------------------------------------------------KTGMTPALPPPDVTASVGSSTGVASSLSEPSYSSSNCGNHAS-ALHSGIPSQEFASSYNGSYLHSTYSGGQSTPALPSPHPSPLHSAGLLQPP-PPPPP--TLVPSYNTSSPNLSSYNYPPAGYPPQTPVAPGYSPGGAPPP-SAYLPSGIAAPTPLPPSTIPGYSYQSHNHAPIAPT-PLNGSSANTLKRKAFYMTGQGDMDSSYGNFNYSQQRSAQSPMYRMPDNSLVDSTRGNGFDRNADTSSLAFKPTKQSMPTDQQRKFGSQAGRALTPPSYGSSKGSLGSMRSGESFGKFGSPVMSDHGDDSRQHLPHSID-----TATSSSHPAEEQLKNSDANLVEMVTTEILQQTSPVDWSDIAGLEMAKATIKDEVLWPILRPDMFSGLATLPRSILLFGPQGTGRTLLGRCMASQLGAAFLLLSGSALVTKWLGEGEKIVQASFLIARCRQPSVVFISDVDLLLSSQLSEE-SPVNR-IKSELLLQLDGVLSSPE------------------EHVLVVCSTSKPEEIDESLRRYFVKRLLVPLPDATARHQIISQLLSQHNYCLSDKEVTLLVQRTDGFSGLDVVRLCQEALVGPLHGMPGADLSGMIPGQMRPVSYQDFENVFCKIQPSISQKELDTYTEWNKMFGCSQ-", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P39955-1", "uniprot_id": "SAPR1_YEAST", "id": "P39955-1", "name": "Microtubule severing ATPase SAP1", "aln": "--MDSQRSHHILTRLTKIRRRPQQPLTDFTELYSRIANETIYYLNLEEKKRYKEALQGWKALTTDVLFKQTLIEHNYPNTQSYTKDEVSLQNGIRELYHKSVMHLKRVKKLVREEPAPRNDMPSSKTYTNHSSSFTRSTEPPPVFQMVPGRMMKTLRNRNACGYKTAYSNPSLSSYGNSTSIKRGEDAENIRVNFVPSKPLSNNASRQHKNPIEHNDPPLKKETELYSDKYISEPILIDLTNDEDDHDVGILKGHNVFDEEESDGFEFDVSDYYDNFSEVDVEEEEEEKEERRRIKTLEAIQQQMSDLSVTSSTSSNKSVSSSENVPGSCIQSLPTTAPALPSLPPPPLLNVDRASSTGALKPHSLETSTTMDSSKIRNPQISKLMKNNHVPYLKGTKSTPTLITKSTPTFITRSKSNTKPIIKSNASSPTSSLTVPNSVIQKPKTAAMAAKRVLNSKKVASNPALNTTKKSHPILKSKTAKVPNSSSKKTSSHPSRPVSNSKPYSHGASQNKKPSKNQTTSMSKTNRKIPAQKKIGSPKIEDVGTEDATEHATSLNEQREEPEIDKKVLREILEDEIIDSLQGVDRQAAKQIFAEIVVHGDEVHWDDIAGLESAKYSLKEAVVYPFLRPDLFRGLREPVRGMLLFGPPGTGKTMLARAVATESHSTFFSISASSLTSKYLGESEKLVRALFAIAKKLSPSIIFVDEIDSIMGSRNNENENESSRRIKNEFLVQWSSLSSAAAGSNKSNTNNSDTNGDEDDTRVLVLAATNLPWSIDEAARRRFVRRQYIPLPEDQTRHVQFKKLLSHQKHTLTESDFDELVKITEGYSGSDITSLAKDAAMGPLRDLG-DKLLETEREMIRPIGLVDFKNSLVYIKPSVSQDGLVKYEKWASQFGSSGS", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "Q9VQN8-1", "uniprot_id": "FIGL1_DROME", "id": "Q9VQN8-1", "name": "Fidgetin-like protein 1", "aln": "---MSDEQSSWRSKLLLICQQTRS------------SSESIHFAALKDHHARLQACE-------------------------------SMEKAMKERCQKKITMSRRTKR-------------------------------------------------------------------------------------------------------------------------------------------GITHAGYLFEMPHNSVFEPECRGFYESCQQTEMASS----------------DLQAPALEVSSTYPVQQAVKSR----------------------PEGQFPESRNNSTKKIDAQQYSSESSSQSG---------------------------------FGFRTAREQLIMDELKKKNRQATSEVDAVPTGMMNFRKKTLGGKRTVSSN-----------------FVSPVAQNDNSTSSRSSSIPP------------------------------------------------------------------------------------ALAHLDSKMVDHILGESMHDFKPVAWEDIAGLESAKSTFLEAIIMPLRRPDLFTGVRCPPRGVLLFGPPGTGKTLIAKSIASQAKAKFFSINPSSLTSKWVGDAEKLVKTLFAVAAAHQPAIIFIDEVDSLLSKRS-ANENESTLRLKNEFLIHLDGAASNEE------------------IRVLVIGATNRPQELDEAVRRRFVRRLYVPLPTREARQKIIEKLIHQVKHNLDVRQVIELAELTDGYSGADVDTLCRYASMAPLRSLTPDQMEVIETHQLPAVTMDDFKQALRVISKSVSSEDCKQFEAWNEIYGVRH-", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : ... . : *: * : . :. : .. . :: *: . : . . . . . . : *: . :.. : * : . :: :.. . . . : . .* . : : .. . : . . . :** . * * : . : * : . * *.*****: .* : : :: *. *.* * *: *.:***** ***:*::.:.:*:: : *: : *.*.:*::*:.**:::: * :* .*:::*:.::* ::..: : . . ::.*:*:: . : :::*: :*. * .:**: ** *::* :*** :*: : :*: : :: * :. *.: *:*:** *: *.: * :.**: : .: : .: **:: : *. *:*.. : * . :* ", "identical_positions": 81, "similar_positions": 171, "identity": "9.0%" }, { "cls_id": "homologset.agr.MGI:1890648", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8BPY9-1", "uniprot_id": "FIGL1_MOUSE", "id": "Q8BPY9-1", "name": "Fidgetin-like protein 1", "aln": "-------METSSSMSVETTRSVQVDEWQKNYCVVTSSICTPKQKADAYR--------------------------------------------------------------------------------------------------ALLLHIQYAYANSEISQVFATNLFKRYTEKYSAIIDSDNVVTGLNNYAESIFALAGSRQADSNKWQSGLSIDNVFKMSCVQEMMQAGKKFEESLLEPADASVVLCKEPTAFEVPQLSVCGGSEDADILSSSGHDTDKTQAIPGSSLRCSPFQSARLPKETNTTKTCLTSSTS-------------------------------LGESATAAFHMTPLFGNTEKDTQSFP------------------KTSTGLNMFLSNLSCVPSGCENPQERKAFNDSDIIDILSNPTLNKAPSKTEDRGRREDNS----------------LPTFKTAKEQLWVDQKKKGHQSQHTSKSSNGVMKKSLGAGRSRGIFGKFVPPVSNKQDGSEQH-AKKHKSSRAGSAEPAHLTDDC------------------------LKNVEPRMVELIMNEIMDHGPPVHWDDIAGVEFAKATIKEIVVWPMMRPDIFTGLRGPPKGILLFGPPGTGKTLIGKCIASQSGATFFSISASSLTSKWVGEGEKMVRALFAVARCQQPAVIFIDEIDSLLSQRG-DGEHESSRRIKTEFLVQLDGATTSSE------------------DRILVVGATNRPQEIDEAARRRLVKRLYIPLPEASARKQIVGNLMSKEQCCLSDEETDLVVQQSDGFSGADMTQLCREASLGPIRSLHAADIATISPDQVRPIAYIDFENAFKTVRPTVSPKDLELYENWNETFGCGK-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6GX84-1", "uniprot_id": "FIGL1_RAT", "id": "Q6GX84-1", "name": "Fidgetin-like protein 1", "aln": "-------METSS------SRSVQVDDWQKNYSVVASSICTPKQKADAYR--------------------------------------------------------------------------------------------------ALLLHIQDAYANSEISQVFATNLFKRYTEKYSAIIDSDNVVTGLNNYAESIFALAGSQQADSDKWQSGLSINNVFKMSTVQEMMQAGQKFKESLLEPADASVVMCKEPTIFEVPQLGVCGGSEEADLLSSSVHGTEKTQAIPGNSLRCSPFQSTLFPMATN-TKTCLTSSAP-------------------------------SGESTTATFHRTPLFGNTKKEPQSFP------------------KTSTGLNMFLSNPSCVPSGCENPRERKAFNDSDTINMLSNPTLNKAPSKTEDSGQREDNS----------------LPTFKTAKEQLWADQKKRSHQSQHTSKSFNGAIKKSLGAGRSRGIFGKFVPPVSNKQDGSEQNGNVKPKSSRAGSAEPAHLTDDR------------------------LKNVEPRMVELIMNEIMDHGPPVHWEDIAGVEFAKATIKEIVVWPMMRPDIFTGLRGPPKGILLFGPPGTGKTLIGKCIASQSGATFFSISASSLTSKWVGEGEKMVRALFAVARCQQPAVIFIDEIDSLLSQRG-DGEHESSRRIKTEFLVQLDGATTSSE------------------DRILVVGATNRPQEIDEAARRRLVKRLYIPLPEASARKQIVVNLMSKEQCCLTDEETELVVQQSDGFSGADMTQLCREASLGPIRSLHTADIATISPDQVRPIAYIDFENAFRTVRPSVSPKDLELYENWNKTFGCGK-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q6PIW4-1", "uniprot_id": "FIGL1_HUMAN", "id": "Q6PIW4-1", "name": "Fidgetin-like protein 1", "aln": "-------MQTSS------SRSVHLSEWQKNYFAITSGICTG-PKADAYR--------------------------------------------------------------------------------------------------AQILRIQYAWANSEISQVCATKLFKKYAEKYSAIIDSDNVESGLNNYAENILTLAGSQQTDSDKWQSGLSINNVFKMSSVQKMMQAGKKFKDSLLEPALASVVIHKEATVFDLPKFSVCGSSQESDSLPNSAHDRDRTQDFP-ESNRLKLLQNAQPPMVTNTARTCPTFSAP-------------------------------VGESATAKFHVTPLFGNVKKENHSSA------------------KENIGLNVFLSNQSCFPAACENPQ-RKSFYGSGTIDALSNPILNKACSKTEDNGPKEDSS----------------LPTFKTAKEQLWVDQQKKYHQPQRASGSSYGGVKKSLGASRSRGILGKFVPPIP-KQDGGEQNGGMQCKPYGAGPTEPAHPVDER------------------------LKNLEPKMIELIMNEIMDHGPPVNWEDIAGVEFAKATIKEIVVWPMLRPDIFTGLRGPPKGILLFGPPGTGKTLIGKCIASQSGATFFSISASSLTSKWVGEGEKMVRALFAVARCQQPAVIFIDEIDSLLSQRG-DGEHESSRRIKTEFLVQLDGATTSSE------------------DRILVVGATNRPQEIDEAARRRLVKRLYIPLPEASARKQIVINLMSKEQCCLSEEEIEQIVQQSDAFSGADMTQLCREASLGPIRSLQTADIATITPDQVRPIAYIDFENAFRTVRPSVSPKDLELYENWNKTFGCGK-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VQN8-1", "uniprot_id": "FIGL1_DROME", "id": "Q9VQN8-1", "name": "Fidgetin-like protein 1", "aln": "----------------------------------------MSDEQSSWR--------------------------------------------------------------------------------------------------SKLLLICQQTRSSSESIHFAA----------------------LKDHHARLQACESMEKAMKERCQKKITMS---------RRTKRGITHAGYLFEMPHN--------SVFEPECRGFYESCQQTEMASS-------------------DLQAPALEVSSTYPVQQAVKSRP-------------------------------EGQFPESRNNSTKKIDAQQYSSESSS------------------QSGFG--------------------------------------------------------------------------FRTAREQLIMDELKK---KNRQATSEVDAVPTGMMNFRKKTLGGKRTVSSNFVSPVAQNDNSTSSRSS---------SIPPA------------------------LAHLDSKMVDHILGESMHDFKPVAWEDIAGLESAKSTFLEAIIMPLRRPDLFTGVRCPPRGVLLFGPPGTGKTLIAKSIASQAKAKFFSINPSSLTSKWVGDAEKLVKTLFAVAAAHQPAIIFIDEVDSLLSKRS-ANENESTLRLKNEFLIHLDGAASNEE------------------IRVLVIGATNRPQELDEAVRRRFVRRLYVPLPTREARQKIIEKLIHQVKHNLDVRQVIELAELTDGYSGADVDTLCRYASMAPLRSLTPDQMEVIETHQLPAVTMDDFKQALRVISKSVSSEDCKQFEAWNEIYGVRH-", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P40328-1", "uniprot_id": "TBP6_YEAST", "id": "P40328-1", "name": "Microtubule severing ATPase YTA6", "aln": "--MAHEKFSIPENFTLAQSLQLLYSVVKNQYKNLADLIINSKGNKDTVTYGKIHKNLDTLLVYVNEGLRKIEKTYT-------------------------LKKGLGNLVVDHPELRSIIED---------------------FQILGQDIRIARRKAETLMAEGNGSPSLSSSSSVLGLGTGNGLRFPKLWRMGSKRDKLKEADEKEAKINKQADNIRRARKLEEEKKLGAKLQYERDLELQ--------REKLIELKVKEKVEFEVAQKLE--------EERVKREEEERKHREQAEKKRISTLKHERKTNYKSRAS---------------------------LDNFSSSSKSSGKIDNSLIKRRSLDVVRTSGERVRTPVR---------KSMEAAEIGMAAQLAWSQYQNGANHSKVSNNGSHSNELQIRYKPTPPLKKRYDYKKPTVN----------------RPIIKSPTLNRQNSKSSRNIPTNSK-LKASKSNTNKVSRRNEQNLEPSSPVLVSATAVPAE---SKPMRSKSGTPDKESSASSSLDSRKE--------------DILKSVQGVDRNACEQILNEILVTDEKVYWEDIAGLRNAKNSLKEAVVYPFLRPDLFKGLREPVRGMLLFGPPGTGKTMIAKAVATESNSTFFSVSASSLLSKYLGESEKLVRALFYMAKKLSPSIIFIDEIDSMLTARS-DNENESSRRIKTELLIQWSSLSSATAQSEDRNN--------TLDSRVLVLGATNLPWAIDDAARRRFSRKLYIPLPDYETRLYHLKRLMAKQKNSLQDLDYELITEMTEGFSGSDLTSLAKEAAMEPIRDLG-DKLMFADFDKIRGIEIKDFQNALLTIKKSVSSESLQKYEEWSSKFGSNGS", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P39955-1", "uniprot_id": "SAPR1_YEAST", "id": "P39955-1", "name": "Microtubule severing ATPase SAP1", "aln": "MDSQRSHHILTRLTKIRRRPQQPLTDFTELYSRIANETIYYLNLEEKKRYKEALQGWKALTTDVLFKQTLIEHNYPNTQSYTKDEVSLQNGIRELYHKSVMHLKRVKKLVREEPAPRNDMPSSKTYTNHSSSFTRSTEPPPVFQMVPGRMMKTLRNRNACGYKTAYSNPSLSSYGNSTSIKRGEDAENIRVNFVPSKPLSNNASRQHKNPIEHNDPPLKKETELYSDKYISEPILIDLTNDEDDHDVGILKGHNVFDEEESDGFEFDVSDYYDNFSEVDVEEEEEEKEERRRIKTLEAIQQQMSDLSVTSSTSSNKSVSSSENVPGSCIQSLPTTAPALPSLPPPPLLNVDRASSTGALKPHSLETSTTMDSSKIRNPQISKLMKNNHVPYLKGTKSTPTLITKSTPTFITRSKSNTKPIIKSNASSPTSSLTVPNSVIQKPKTAAMAAKRVLNSKKVASNPALNTTKKSHPILKSKTAKVPNSSSKKTSSHPSRPVSNSKPYSHGASQNKKPSKNQTTSMSKTNRKIPAQKKIGSPKIEDVGTEDATEHATSLNEQREEPEIDKKVLREILEDEIIDSLQGVDRQAAKQIFAEIVVHGDEVHWDDIAGLESAKYSLKEAVVYPFLRPDLFRGLREPVRGMLLFGPPGTGKTMLARAVATESHSTFFSISASSLTSKYLGESEKLVRALFAIAKKLSPSIIFVDEIDSIMGSRNNENENESSRRIKNEFLVQWSSLSSAAAGSNKSNTNNSDTNGDEDDTRVLVLAATNLPWSIDEAARRRFVRRQYIPLPEDQTRHVQFKKLLSHQKHTLTESDFDELVKITEGYSGSDITSLAKDAAMGPLRDLG-DKLLETEREMIRPIGLVDFKNSLVYIKPSVSQDGLVKYEKWASQFGSSGS", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . . : . : : :. : : . .: : . . . . ::: : .. .: . .. . .: : :: . . *: * : * *:****:. ** :: * :: *: ***:* *:* * :*:***********::.:.:*::: :.***:..*** **::*:.**:*::** :* .*::**:**:**:: *. .*:**: *:*.*:*:: .. :: *:**:.*** * :*:*.***: :: *:*** .:* . .*: : : * : :.: ::.:**:*: *.: *:: *:*.* .: . : : **:::: : :** .. :* * . :* ", "identical_positions": 96, "similar_positions": 142, "identity": "10.69%" }, { "cls_id": "homologset.agr.MGI:1890651", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0ABK0LKM2-1", "uniprot_id": "A0ABK0LKM2_RAT", "id": "A0ABK0LKM2-1", "name": "Bromodomain and WD repeat-containing protein 1", "aln": "MAEPSPARRPVPLIESELYFLIARYLSAGPCRRAAQVLVQELEQYQLLPKRLDWEGNEHNRSYEELVLSNKHVAPDHLLQICQRIGPMLDKEAPPSISRVTSLLGAGRQSLLRTAKDCRHTVWKGSAFAALHRGRPPEMPVNYGPPPSLVDIHRGKQLTGCSTFSTAFPGTMYQHIKMHRRILGHLSAVYCVAFDRTGHRIFTGSDDCLVKIWSTHNGRLLSTLRGHSAEISDMAVNYENTLIAAGSCDKIIRVWCLRTCAPVAVLQGHTGSITSLQFSPMAKGPQRYMVSTGADGTVCFWQWDLE---SLKFSPRPLKFTEKPRPG-VQMLCSSFSVGGMFLATGSTDHVIRMYFLGFEAPEKIAELESHTDKVDSIQFCNNGDRFLSGSRDGTARIWRFEQ-LEWKSILLDMAARISG-DTSAEEERFMKPKVTMIAWNQDDSTVVTAVNDHVLKVWSSYTGQLLHNLLGHADEVFVLETHPFDSRIMLSAGHDGSIFIWDITKGIKMKHYFNMIEGQGHGAVFDCKFSQDGQHFACTDSHGHLLIFGFG-CSKPYEKIPDQMFFHTDYRPLIRDSNNYVLDEQTQQAPHLMPPPFLVDVDGNPHPTKFQRLVPGRENSADEHLVP-----QLGYVATSDGEVIEQVISLHTNDSGDASPESSVLDGMIRQLQQQQDLRLGVDQDV--TANGLPNEEGTPRRGSFRRLSLDIQSPPNIGLRRSGQVEGVRQMHQN--------------------------APRSQIATERDLQAWKRRVVVPEAPPGVFRRLEDIRIERGEEERNLYVIGRKKKTFQLPQ----KSNSMVLVSQSRQRTCRRKYANYSRR---------------NAGQCELSSGNESSGSVRHETSCDQSEGSCSSEDDEWRSDRRSGSDSDSPSESSSQYSDWTADTGVHLEPPLRTSCRRRVTRFCSTSEDE-----------MSTENISPPKRRRKRRKESKPKRESLRRTTPAELANMEPLYEFHPPVWITDTTLRKSPFVPQMGDEVMYFRQGHEAYIEAVRRNNIYELNPNKEPWRKMDLRDQELVKIVGLRYEVGPPTLCCLKLAFIDPATGRLTDKSFSIRYHDMPDVIDFLVLRQFYDEARQRNWQPSDRFRSIIDDAWWFGTVLSQEPYQPQYPDSHFQCYSVRWDNTEIEKLSPWDMEPIPDNVDPPEELGASISVTSDELEKLLYKPQDGEWGQRSRDEECERIISGIDQLLNLDIAAAFAGPVDLCTYPKYCTVVAYPTDLYTIRMRLVHRFYRRLSALIWEVRYIEHNARTFNEPESVIARSAKKITDQLLKFIKNQDCTNILELCNTSDSD-GDSADD--LDDSDLPKTSSGRRRVHNWKRRSRGSS--------CIESDWRRQCKALLILIFQCEDSEPFRQPVDLVEYPDYRDIIDTPMDFGTVRETLEAGNYDSPVEFCKDIRLIFSNAKAYTPNKRSKIYSMTLRLSALFEEKMKKISFDFKIGQKFKEKLRRSQRFKQRQKCNGAVPVDRSMRSVKQKQFRSQTKVIPQLMCSPSQSTSSKVPLSATRKTSAGVSSGCTSGDSSDSAGSLERVRRHRAETLRSGSVLFGSEMEDFLATSSSSSSSNSSDESKESSGAQECSLRSGVLRSSNLRVTRTRAARRKAGSVSLENGCGRKATRKRVYLSDSDNHSVETDENLKS-KAGSSRKVLRKCAAVAASKIKLMSDAED-SSSESPCSGRKLPHRNASAVARKKLLHNSDD-QSLKSET--EEVRDRNQALLMSSPHAVQNCIS-----DSESDSDLQAARKTWHANGCTSHPAAACKAKSRPIESSEEDSRCHESDHGPSSTVDPLTSGQKLGADSISEEADSEPGSS------ALGKNTHLSKKAKILSDSEDCEEKYGER---RGPEVEGSPVSEALR-EAVIVPQCLSHHGPETDVDSDGSAVREKSHSNVNDSVSRENGQRKKVSRKRFCSSDSESNLQVIQKSPIDQTSPSRITRS-AGMVTDKTKLTSDAEDVSLESVCTRSKRRRKKPVRFACTTAKSIPSSEGKHARCEVPEEQSACRSSLAEPEQQGSAENASQAANADLDFEGSSSFEQTKSIQKRQMDSVCIRAPSKTQNSSAGPSQEDPKSHTQDSDIS--LSSESVLAQKAIGENNFEEELNYGLRRWNGRRLRTYGKAPLSRTAPVTPSLQAAAEVRVKRRRVHPEVDGEDIPGQMGSSGCGPDTSPKSSDLGSVTESDVDCTDNTKAQRRKKRKGKTRVLSQESVRKDREPHTKTRPCMFNEKEAVQMHSDTLKPKTVPEKIPRRCAAIAANKIKTMCNLKEVVSGPENVGIRTNSRKLPYRQASAAAKKKLLSVYKEDDALIHSENEEE--------VYLRRFRSQKEKAQQSP--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q921C3-1", "uniprot_id": "BRWD1_MOUSE", "id": "Q921C3-1", "name": "Bromodomain and WD repeat-containing protein 1", "aln": "MAEPSPARRPVPLIESELYFLIARYLSAGPCRRAAQVLVQELEQYQLLPKRLDWEGNEHNRSYEELVLSNKHVAPDHLLQICQRIGPMLDKEVPPSISRVTSLLGAGRQSLLRTAKDCRHTVWKGSAFAALHRGRPPEMPVNYGPPPSLVEIHRGRQLTGCSTFSTAFPGTMYQHIKMHRRILGHLSAVYCVAFDRTGHRIFTGSDDCLVKIWSTHNGRLLSTLRGHSAEISDMAVNYENTLIAAGSCDKIIRVWCLRTCAPVAVLQGHTGSITSLQFSPMAKGPQRYMVSTGADGTVCFWQWDLE---SLKFSPRPLKFTEKPRPG-VQMLCSSFSVGGMFLATGSTDHVIRMYFLGFDAPEKIAELESHTDKVDSIQFCNNGDRFLSGSRDGTARIWRFEQ-LEWRSILLDMSARISG-DTSSEEERFMKPKVTMIAWNQDDSTVVTAVNDHVLKVWSSYTGQLLHNLLGHADEVFVLETHPFDSRIMLSAGHDGSIFIWDITKGIKMKHYFNMIEGQGHGAVFDCKFSQDGQHFACTDSHGHLLIFGFG-CSKPYEKIPDQMFFHTDYRPLIRDSNNYVLDEQTQQAPHLMPPPFLVDVDGNPHPTKFQRLVPGRENSADEHLVP-----QLGYVATSDGEVIEQIISLHTNDSGDASPESSVLDGMIRQLQQQQDQRLGVDQDG--TANGLPSGEGTPRRGSFRRLSLDIQSPPNIGLRRSGQVEGVRQMHQN--------------------------APRSQIATERDLQAWKRRVVVPEAPPGMFRRLEDIRIERGEEERNLYVIGRKKKTFQVPQ----KSNSMVLVSQSRQRTCRRKYANYSRR---------------NADQCELSSGNESSGSVRHETSYDQSEGSCSSEDDEWRNDRRSGSDSDSSSDSSSQYSDWTADTGINLQPPLRMSCRRRVTRFCSTSEDE-----------MSMENISPPKRRRKRRKESKPKRESLRRMTPAELANMEHLYEFHPPVWITDTTLRKSPFVPQMGDEVMYFRQGHEAYIEAVRRNNIYELNPHKEPWRKMDLRDQELVKIVGLRYEVGPPTLCCLKLAFIDPATGRLTDKSFSIRYHDMPDVIDFLVLRQFYDEARQRNWQPCDRFRSIIDDAWWFGTVLSQEPYQPQYPDSHFQCYIVRWDNTETEKLSPWDMEPIPDNVDPPEELGASISVTSDELEKLLYKPQEGEWGQRSRDEECDRIISGIDQLLNLDIAAAFAGPVDLCTYPKYCTVVAYPTDLYTIRMRLVNRFYRRLSALIWEVRYIEHNARTFNEPESVIARSAKKITDQLLKFIKNQDCTNISELCNTSDNDEDDSADD--LDDSDLPKTSSGRRKVHNWKRRSRASG--------CIESDWRRQCKALLILIFQCEDSEPFRQPVDLDEYPDYRDIIDTPMDFGTVRETLEAGNYDSPVEFCKDIRLIFSNAKAYTPNKRSKIYSMTLRLSALFEEKMKKISFDFKIGQKFKEKLRRSQRFKQRQNCNGAVPGDRRRRNVKQKQFKSQTKVIPQLMCPPSQSTSSKVPLSATRKTSAGVSSGFTSGDSSDSAGSLERVRRQRPEVLRSGSVLFGSEMEDFLATSSSSSASNSSEESKASPGARESSLRSGVLRGSNLGVTRTRAARRKAGSVSLENGCGRKATRKRVYLSDSDNNSVETDENLKNRKCGSSRKVLRKCAAVAASKIKLMSDAED-SSSESPCSGRKLPHRNASAVARKKLLHNSDD-QSLKSET--EELKDQNQSLLISGPHSVHNSIS-----DSESDSDLRATRKTWNANGCTSHTAATCKTKSRPIESSEEDSRCHGSDHGPSSTGDPSTSGQKLRADSISEEADSEPESS------VLCKNTHLCKKAKILSDSEDCEEKCGER---RGPEVEGSPVSEALR-EAILAPQCLSHRGSETDVDSDGGAVREKSYSNENGSVSLENGQRRKVSRK--SSSDKESNLQVTQKSPKDRSSPSRITQR-ASVATDKMKLTSDAEDLSLESVCTRSKRRRKKPARFACTPAKTALSSEEKHAHCEVPEAQPACRNKLPEPEHQDSAENPSQAASADLNSGGGSSFEQRKSIQSRQMGAVCVRPPPKTQSSSAGLSQENARSQTLDSETS--LPSESVLTQKATVESNFEEELNYGLRRWNGRRLRTYGKAPLSRTAQVTPSLQASAEVGVKRRRMHPEVDGEDVPGQMGSSGCGPDTSPKASDLGSVTDSDVDCTDNTQTQRKKKRKGKARVLSKESVRKDREPHTKMRPCMLNEKDAVQMHSDTLKAKTVPEKVPRRCATVAANKIKMMCNLKEVVSGPENVGIRTISRKLPYRQASAAAKKKLLSVYKEDDAPIHSENEKE--------LYLRRFRSRKEKAQPTPR-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9NSI6-1", "uniprot_id": "BRWD1_HUMAN", "id": "Q9NSI6-1", "name": "Bromodomain and WD repeat-containing protein 1", "aln": "MAEPSSARRPVPLIESELYFLIARYLSAGPCRRAAQVLVQELEQYQLLPKRLDWEGNEHNRSYEELVLSNKHVAPDHLLQICQRIGPMLDKEIPPSISRVTSLLGAGRQSLLRTAKDCRHTVWKGSAFAALHRGRPPEMPVNYGSPPNLVEIHRGKQLTGCSTFSTAFPGTMYQHIKMHRRILGHLSAVYCVAFDRTGHRIFTGSDDCLVKIWSTHNGRLLSTLRGHSAEISDMAVNYENTMIAAGSCDKIIRVWCLRTCAPVAVLQGHTGSITSLQFSPMAKGSQRYMVSTGADGTVCFWQWDLE---SLKFSPRPLKFTEKPRPG-VQMLCSSFSVGGMFLATGSTDHVIRMYFLGFEAPEKIAELESHTDKVDSIQFCNNGDRFLSGSRDGTARIWRFEQ-LEWRSILLDMATRISG-DLSSEEERFMKPKVTMIAWNQNDSIVVTAVNDHVLKVWNSYTGQLLHNLMGHADEVFVLETHPFDSRIMLSAGHDGSIFIWDITKGTKMKHYFNMIEGQGHGAVFDCKFSQDGQHFACTDSHGHLLIFGFG-CSKPYEKIPDQMFFHTDYRPLIRDSNNYVLDEQTQQAPHLMPPPFLVDVDGNPHPTKYQRLVPGRENSADEHLIP-----QLGYVATSDGEVIEQIISLQTNDNDERSPESSILDGMIRQLQQQQDQRMGADQDT--IPRGLSNGEETPRRG-FRRLSLDIQSPPNIGLRRSGQVEGVRQMHQN--------------------------APRSQIATERDLQAWKRRVVVPEVPLGIFRKLEDFRLEKGEEERNLYIIGRKRKTLQLSH----KSDSVVLVSQSRQRTCRRKYPNYGRR---------------NRSWRELSSGNESSSSVRHETSCDQSEGSGSSEEDEWRSDRKSESYSESSSDSSSRYSDWTADAGINLQPPLRTSCRRRITRFCSSSEDE-----------ISTENLSPPKRRRKRKKENKPKKENLRRMTPAELANMEHLYEFHPPVWITDTTLRKSPFVPQMGDEVIYFRQGHEAYIEAVRRNNIYELNPNKEPWRKMDLRDQELVKIVGIRYEVGPPTLCCLKLAFIDPATGKLMDKSFSIRYHDMPDVIDFLVLRQFYDEARQRNWQSCDRFRSIIDDAWWFGTVLSQEPYQPQYPDSHFQCYIVRWDNTEIEKLSPWDMEPIPDNVDPPEELGASISVTTDELEKLLYKPQAGEWGQKSRDEECDRIISGIDQLLNLDIAAAFAGPVDLCTYPKYCTVVAYPTDLYTIRMRLVNRFYRRLSALVWEVRYIEHNARTFNEPESVIARSAKKITDQLLKFIKNQHCTNISELSNTSEND-EQNAED--LDDSDLPKTSSGRRRVHDGKKSIRATN--------YVESNWKKQCKELVNLIFQCEDSEPFRQPVDLVEYPDYRDIIDTPMDFGTVRETLDAGNYDSPLEFCKDIRLIFSNAKAYTPNKRSKIYSMTLRLSALFEEKMKKISSDFKIGQKFNEKLRRSQRFKQRQNCKGDSQPNKSIRNLKPKRLKSQTKIIPELVGSPTQSTSSRTAYLGTHKTSAGISSGVTSGDSSDSAESSERRKRNRP--ITNGSTLSESEVEDSLATSLSSSASSSSEESKESSRARESSSRSGLSRSSNLRVTRTRAAQRKTGPVSLANGCGRKATRKRVYLSDSDNNSLETGEILKA-RAGNNRKVLRKCAAVAANKIKLMSDVEENSSSESVCSGRKLPHRNASAVARKKLLHNSEDEQSLKSEIEEEELKDENQLLPVSSSHTAQSNVDESENRDSESESDLRVARKNWHANGYKSHTPAPSKTKFLKIESSEEDSKSHDSDHACNRTAGPSTSVQKLKAESISEEADSEPGRSGGRKYNTFHKNASFFKKTKILSDSEDSESEEQDREDGKCHKMEMNPISGNLNCDPIAMSQCSSDHGCETDLDSDDDKIE-KPNNFMKDSASQDNGLSRKISRKRVCSSDSDSSLQVVKKSSKARTGLLRITRRCAATAANKIKLMSDVEDVSLENVHTRSKNGRKKPLHLACTTAKKKLSDCEGSVHCEVPSEQYACEGKPPDPDSEGSTKVLSQALNGDSDSEDMLNSEHK----HRHTNIHKIDAPSKRKSSSVTSSGEDSKSHIPGSETDRTFSSESTLAQKATAENNFEVELNYGLRRWNGRRLRTYGKAPFSKTKVIHDS-QETAEKEVKRKRSHPELENVKISETTGNSKFRPDTSSKSSDLGSVTESDIDCTDNTKTKRRK-TKGKAKVVRKEFVPRDREPNTKVRTCMHNQKDAVQMPSETLKAKMVPEKVPRRCATVAANKIKIMSNLKETISGPENVWIRKSSRKLPHRNASAAAKKKLLNVYKEDDTTINSESEKELEDINRKMLFLRGFRSWKENAQ-----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1QKF7-1", "uniprot_id": "A0A8M1QKF7_DANRE", "id": "A0A8M1QKF7-1", "name": "", "aln": "MADTTARNGSISPLESELYYLISRYLSTGPCRKAAEALVCELEENQLLPRRLDWEGNEHPRSYEDLVTANRHIAPDHLLQICKQIGPVLDREVPSGVPGVHSLLGAGRHSLLRTSKDCCASRWKTSTFAALHRGRPPERPLNCKD-ANIVEVCRGRELTGAQRFSSINPVSNYQHMKMHRRILGHLSAVYCIAFDRTGSRIFTGSDDALVKIWSSFDGRLHSTLRGHYAEISDLAVNFENTLIAAGSCDKTIRVWCLRTCAPVAVLQGHSGSITSLQFSPFVKGSKRYMVSTGTDATVCFWQWDVN---NNEFSDRQHKFTERPRPG-VQTVCSSFSPGGMFLATGSTDDVIRIYYLGSGSPEKLAELDSHTDKVDSIQFCHSGERFVSGSRDGTARIWRLHQRHQWKSVLLDMSATLPGSAPLTDDENFFKPKVTMVSWDRHDNTVITAVNNHLLKVWNSYTGQLLHVLKGHEAEVFVLEPHPYDPRIMLSAGHDGNVFVWDLIKGTKTMHYFNMIEGQGHGAVFDCKFTPDGHRFAMTDSHGHLVIFGFG-SSKPYEKLPDQVFFHTDYRPLIRDTNGFVLDEQTQQAPHLMPPPFLVDVDGNPHPPRFQRLVPGRENIADEHLVP-----QLGYVATSDGEVVEQVISQQSAESEEVR--HSALDFAIRQLREHQDRQSGAPGEAGVPAAARVPEPGTPRRVSVNER-MEVQSPPNVGLRRSGQVEGVRQMHQN--------------------------APRSQMATERDLQAWRRRVVIPELTPSGYRAQESFRIAKGDEEVNLYNTKKRRVTHSTFRDDSDEEGPCLKRTQSRKRQKNQERKENLAE---------------EYIEFSCEEGEETASSEASEVEGSDIDSSAEDEE-EWKSD--------SSSRSSSDYSDWTADAGISVR--TSDSSRRRTTRRISSSEEEDEEDDEEEEEPADEEPAVGEEETSSPRKHKKAKSKTPKHSKPRPSINREISNEFRPPAWITDVVPRKSPFVPQMGDEVIYFRQGHEAYVDAVCRMNLYPINLDKQPWKKMQLRDQEFVKITGIKYEVCPPTLCCLKLTQIDPGTGKITDRTFSIKYHDMADVIDFLVLRQSYDEARNRVWTSNDRFRSVIDDAWWFGAIVCHEPYQSEYPDSHFQCFKVKWDNGETEKLSPWDVEAIPENAEQPESASAGVPVTDEEMMDILYKPQRGEWGDRGREQESARIIAGIEQLMTVDITAPFSGPVDLTQYPTYCTVIAYPTDLNTIKLRLKHNFYRRLSALIWDVKHIEQNAKTFNEPRSKIAQSAKIITNVLIKFISKLHCTDIMEIYNAVENMEYSDDEE--MDDIDAPGTSAGQR----LRQPSVEVV--------LDRDAWKDHCKRLLDYMFECEDSEPFRDPVDQSDYPDYTNIIDTPMDLGTVRQTLEEDRYENPIDVCKDIRLIFANAKAYTPNKRSKIYSMTLRLSAFFEENIRKIISDYKTAIKSSLKLRRSQRCRKKSQHQESVSFSQG----STRQKRATIKTQENTEQSTAKSTSAKVSGPERRRAHEAKETFRRS--SSSSSGSDQDSK----------QSLSQSDEDD--EHSSSSRAMRRETRATRKKAAQNKGAKSRRPESHVKMNGRSRSHERQKPRTSSDSDH------------EPSQGSDEASENESS-PSVSRRPRTRKTAMAAVNKMKLIDTLGDEEGTDDEGGGG-STRPATRASKRSAVIQSSSDSDDEEEAAASQEESNESGSSASEGEKSAG---------SADSDSSSHSKKNSRTAGRRPCRRPAEKKETSPLTNGHGTKRQWEESDDNSEDGGSPIESENLESDNDLVVRRKSTRRTA---------KAAVSKIKKINNTDAEEEENCTRDRRQKHRSITQESENSSDEEVETTKTLKHPHQNGRKVDAK-ELKRCKAPSERQEQSPAAKQKTTHKKSSATDACMSTTQDSEELSDDVEKSVTHRKRIASE------DEENQSDDADQRRVPKNRNRSSNARKQ---------------------------------KLCASSDESSSESDEKADRGRIKSEGTSSDEWQ----------------------KSDTSEEDKKTHPQRKPCP--TVASKGVSLRTRPKKNYIMEDS---------------------EEEFSPKMDVQAKNGVKNQQAN-----SRTRKPSGGGFKRKHGGSSESDADSKSSRSSDGNKLAEAQRKS-----AKRFKQLMGSTDSESDFETR---CKSENGRAQRSQGKLPTVSRQRRKQSESDKGSNDNGSNFESEESESEASSGSRSSPKRRLRDRDRGTARSRKPRRVVSDDDSDVSFEKPRR-----GRRIQTRNKGKRTVNYQDSE--", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VC96-1", "uniprot_id": "Q9VC96_DROME", "id": "Q9VC96-1", "name": "", "aln": "--METRQPSSGDDLKPELYFLISKFLAAGPLEETAKVLIRELEEKKVLPRRLDWQGNEHEQTFEELERKYKHIGANHLLEICSRLGPLVDRELPPSVPGINSLLGTGRQNLLRTKETVYCHRSLRDYCTRLNGVSLPDS-VLTKPTHNLDRVLTGREHGGEVRRKLLVPTDLYRRTKLLRRTVGHLSSVYCVLFDRTGRYIITGADDLLIKIWSAADGRLLATLRGASSEITDIAINLDNTMLAAGSLDHILRVWDMQTTSPIAVLSAHTGMITSVNFCPSPRSDLKYLVTTSTDGSIAFWQYSTPRGQKITFAPKPTQYHEKLRPGQAQMMCTTFSPGGIFLAAGSADHHVRVYMMGEDGPKRILETEAYTDAVDSVQWSHRGLRFISGSKDGTAHIWTFES-QQWKSSKLCMTERLAS---CPEPEEGKRLKVTMVAWDASDRYVITAVNDFTIKIWDSKSAKLHRVLRGHKDELYVLESNPRDEHVLLSAGHDGQVFLWDIEQGVCVANFLNDIDGQGHGSVFDAKWSPDGTMIAATDSHGHILIFGLGVCIEKYKMLPTELFFHTDFRPLLRDAQHHVVDEQTQIMPHLMPPPFLVDADGNPHPSRFQRFVPGRESCSLDQLIPNLTVGVDGVVIDDGGAGGDAVVAAAPAEAPPAALPPAAAGGPQGANYSHIDRMIAALANRQSVNVNANDANPTNGNQSFERLTNRQMPDSNGRQSSRGNVLGSRLSTPRQGWGAAAAAPVEDQAGPSQPPAEPAAEPGQAQVQQALPLKFIRRTYVRPMKYPQLQNLKQTIYSAGQFEKQEYKREMRRRPIMINTASAASSQQPGSVGRPRNTRGNGGGARAGRRRGPQPAGGQPQPAYRTRAVRDQEPEHYDEVAPPPEEEEEDVSSNSSGDTSYSNVEENLEDSSDESETDSSDYSDWVADTPGPNLEPPKRSKRKPLSRRPRSSDDS---------------SDDERAGRSRGGQVTARKVGRKTVLFPPTDANGEIPELYRPAEWLSEVIPRKAPYYPQMGDEVVYFRQGHAKYLDAVRLKKVYKLSHSSEPWNFHTLRDHELVRVIGIKYEIRPPRLCCLKLAIID-EEGNMTGTTFKIKYHDMPDVLDFLVLRQTFDLAVQRNWSIGDRFRCMIVDGWWMGQIESRHALSADFPDSSFMCFRVRWDNGEYEFMSPWDMEPIDQ-QRVPDEVGGAVPVLPEEIRATLYQPKSEEWHRGDRDGTCRRIINGLEQVMRLSIAEHFLAPVDLNIYPDYAYLIEYPIDLTTIKSRFENHFYRRITSAQFDVRYLATNAEQYNRRHAIIVKHSRIVTDLCLRIIREPDEIDVAAVYHQLADVYHSSESENEVDSDVVPSTSTGPTTSAAAAAARQRVSSARRSTRIHSEGDWRADCRQLLDLMWARTDSAPFREPVDTIDFPDYLEIIATPMDLRTVKEDLLGGNYDDPLDFAKDVRLIFQNSKNYNTNKRSRIYAMTLRLSALFESHIKTVVTSWKAALRRANKNKSGSSGGGRGGSS----------------------------SSPNKRVKKERSTRRNQKPTAAARRLPVANSSEDEDEED-----------------DDDDDDDDDEEEASTRGRSRRRNGVAVSASSSGSNRVTSSSAAQQRRGKSSSSEEEEEEETS----------------AQATSDASSDEEERAQSNDSSPQQTRTRRARQRQRLSDDSNINDSEDSYNPNEGRGSRRRPGAARPSSNRQTNGHSSKRRRLNKS-----------------------------PANAAPGPSLPRRTRRIAGSSAEEAASHSQHDESTQDSQIGRRKGRSASSRSIGNGPSTSAAAAANSSLESPSRNTRANG-----------------TRTSSHLGAENDHSYHLPVRNGRIIESDTDSPVIRPTRQSAKRALMDWGRGSDIEEEEEEEEEDSEEAEEILPTPTKDDLPSTSRAALAQAAAGPSRQLRTNRNTVVRPAQSDDDD---DDDSDNEPLANNQQKNYQSPAKSSSTATVAPHPLS-------------------------LRRRLASPPERNTHMTRSHATSTTSSAAASRAEQQP----------------------AVSTHDHNYLGNVNSSRAPRRILSRHQRNADELDTSLDVLENSRLLSAIANHRRPTSTTNSNSASNVVTRRLRGRASQANSHDEDHEEEEAAASDEGTDGGSSSQSYEDEDEDSDSEDNQPLTSYVSPSNGRPR----RKAKTSSSSATTQERPLRRTRRPPSNNSIANDNDDDDDYVVPRSRRANRGGNQRAGRNQKRPRYNEQSEEEEAAAGYSHRSKRIRNGDAHASSQERSQASTERDQEEEEDGTSVDSEEQQVNVSSRGRVRKPSAKARGIFKE", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . ::.***:**:::*::** ..:*:.*: ***: ::**:****:**** :::*:* :*:..:***:**.::**::*:* *..:. : ****:**:.**** : . : *: *: : .: : *:: * . * *:: *: ** :****:***: ***** *:**:** *:****: :*** :**** :**:*:*:* :**::**** *: :*** ::* :*:***..*:* ***::*.* :. :*:*:*.:*.::.***:. . *: : :: *: *** .* :*::** **:***:**:*. :*:* :* .*::: * :::** ***:*:.: * **:***:****:** :.. :*:* * *: :.. .: *. : ****::*: * *:****:. :*:*.* :.:* : * ** *::***.:* * :::*******.:*:**: :* :::* *:*****:***.*:: ** :* ******::***:* . : *: :* ::*****:***:**:: .*:***** ***********.******.::**:*****. : ::*:* * * ..* : ::: . : : . .: * .. : * . ... . .* *:* * * . * . . : : **. : : :. *: * : * :: . .. :.*: . . . . . . : * . .: ... ..: . : ... .** ****.**: * *: :* :*::. : . * * * * ::*. *:::. **:*: *******:****** *::** ::* :. .:**. ***:*:*:: *::**: ** ******: ** *.: . :*.*:****.**:******* :* * :* * ****.:* *.**:* : .:.. ..::*** * *: *:*** * * :****:*.* : *:. ...:.* :*: **:*: ** .*: . *** *::*:: :.*: * .**** ** *. :: ** ** **: *: :.****::: ::*::: **. :*. .: *.: :: :*: :::* : . :: : : . .. .: :*. * **:* .. *: .*: *: :: ** ***:*** ::*** :** ****: **:: * ..*:.*::..**:**** *:* *..****:**:*******:**.:::.: .:* . : * : .. : . .. : .. . . ::. . : *... . .: :* . *: . .. : . . : . :: : ..: : . .:.* . *. .::. . : ..: . * : * . .. . . . ::: .. :.. .. .* . :. : * . .* * ..: . . :. :. . . : . * . : . * * . : . . : : : . * . : . :: . .. : : :: . . *. . ..: .:* . : .: : . : . * . . *. .. . : ... . .* .* . .. * . : .. . * :.. . .: .: : .... :: . .::: : :: ..: . *: . . . : : ", "identical_positions": 509, "similar_positions": 628, "identity": "21.06%" }, { "cls_id": "homologset.agr.MGI:1890655", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q78Y63-1", "uniprot_id": "PDCL2_MOUSE", "id": "Q78Y63-1", "name": "Phosducin-like protein 2", "aln": "---------MQDPNEDTEWNEILRNFGILPPKE-EPKDEIEEMVLRLQQEAMVK----PY------EKMTLAQLKEAEDEFDEEDIKAIEIYREKRLQEWKALKKKQKFGELREISGNQYVNEVTNAEKD------------------LWVVIHLYRSSVPMCLVVNQHLSVLARKFPETKFVKAIVNSCIEHYHDNCLPTIFVYKNGQIEGKFIGIIECGGINLKLEELEWKLSEVGAIQS------------------DLEENPKKGIADMMVSSIRNISIYD-SDSSGSDTEAK--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8I6B5E6-1", "uniprot_id": "A0A8I6B5E6_RAT", "id": "A0A8I6B5E6-1", "name": "", "aln": "---------MQDPNEDTEWNEILRNFGILPPKE-EPKDEIEEMVLRLQEEAMVK----PY------EKMTLAQLKEAEDEFDEEDIKAIEIYREKRLQEWKALTKKQKFGELREISGNQYVNEVTNAEKD------------------LWVIIHLYRSSVPMCLVVNQHLSVLARKFPETKFVKAIVNSCIEHYHDNCLPTIFVYKNGQIEGKFIGVIECGGINLKLEELEWKLSQVGAIQT------------------DLEENPKKGIADMMVSSIRNVSIYD-SDSSGSDAEAK--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8N4E4-1", "uniprot_id": "PDCL2_HUMAN", "id": "Q8N4E4-1", "name": "Phosducin-like protein 2", "aln": "---------MQDPNEDTEWNDILRDFGILPPKE-ESKDEIEEMVLRLQKEAMVK----PF------EKMTLAQLKEAEDEFDEEDMQAVETYRKKRLQEWKALKKKQKFGELREISGNQYVNEVTNAEED------------------VWVIIHLYRSSIPMCLLVNQHLSLLARKFPETKFVKAIVNSCIQHYHDNCLPTIFVYKNGQIEAKFIGIIECGGINLKLEELEWKLAEVGAIQT------------------DLEENPRKDMVDMMVSSIRNTSIHDDSDSSNSDNDTK--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8MR62-1", "uniprot_id": "PHLP2_DROME", "id": "Q8MR62-1", "name": "Phosducin-like protein 2", "aln": "---------MQDPNEDTEWNDVLRAKGIIGPKA-KEAEITEDQIQKLMDDAIQRRTDLPLNEGQRDKKIDDMSLDELDELEDSEDEAVLEQYRQRRIAEMRATAEKARFGSVREISGQDYVNEVTKAGEG------------------IWVVLHLYANGVPLCALIHHHMQQLAVRFPQTKFVRSVATTCIPNFPEKNLPTIFIYHEGALRKQYIGPLELRGDKLTAEELEFMLGQAGAVPT------------------EITEDPRPQIRDKMLADLE--------DKS-SDFY----", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q12017-1", "uniprot_id": "PLP2_YEAST", "id": "Q12017-1", "name": "Phosducin-like protein 2", "aln": "MQNEPMFQVQVDESEDSEWNDILRAKGVIPERAPSPTAKLEEALEEAIAKQHEN-------------RLEDKDLSDLEELEDDEDEDFLEAYKIKRLNEIRKLQERSKFGEVFHINKPEYNKEVTLASQGKKYEGAQTNDNGEEDDGGVYVFVHLSLQSKLQSRILSHLFQSAACKFREIKFVEIPANRAIENYPESNCPTLIVYYRGEVIKNMITLLELGGNNSKMEDFEDFMVKVGAVAEGDNRLIMNRDDEESREERKLHYGEKKSIRSGIRGKFNVGIGGNDDGNINDDDDGFFD", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * .**:***::** *:: : . *: : . . . :: .*.: :: *.** :* *: :*: * : :: :**.: .*. :* :*** * :. ::*.:** .. . :: : :. * :* : ***. .. .* :: :. **:::* .* : : * :* * : . *::* : :.**: .: . : : . : ..:. .. .* ", "identical_positions": 47, "similar_positions": 88, "identity": "15.72%" }, { "cls_id": "homologset.agr.MGI:1890659", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q6MFZ5-1", "uniprot_id": "TRI39_RAT", "id": "Q6MFZ5-1", "name": "E3 ubiquitin-protein ligase TRIM39", "aln": "MAETSLLEAGASAASTAAALENLQVEASCSVCLEYLKEPVIIECGHNFCKACITRWWEDLERDFPCPVCRKTSRYRSLRPNRQLGSMVEIAKQLQTVKRKIRDESLCSQHHEPLSLFCYEDQEAVCLICAISHTHRAHTVVPMDDATQEYKEKLQKCLEPLEQKLQEITCCKASEERKPGELKRLVESRRQQILKEFEELHRRLDEEQQTLLSRLEEEEQDILQRLRENAAHLGDRRRDLAHLAAEVEGKCLQSGFEMLKDVKSTLEK------------------------------CEKVKTMEVTSVSIELEKNFSHFPRQYFALRKILKQLIADVTLDPETAHPNLVLSEDRKSVKFVETRLRDLPDTPQRFTFYPCVLATEGFTSGRHYWEVEVGDKTHWAVGVCRDSVSRKGELTPLPETGYWRVRLWNGDKYAATTTPFTPLHIKVKPKRVGIFLDYEAGTLSFYNVTDRSHIYTFTDTFTEKLWPLFYPGIRAGRKNAAPLTIRPPTDWE", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9ESN2-1", "uniprot_id": "TRI39_MOUSE", "id": "Q9ESN2-1", "name": "E3 ubiquitin-protein ligase TRIM39", "aln": "MAETSLLEAGASAASTAAALENLQVEASCSVCLEYLKEPVIIECGHNFCKACITRWWEDLERDFPCPVCRKTSRYRSLRPNRQLGSMVEIAKQLQTVKRKIRDESLCSQHHEPLSLFCYEDQEAVCLICAISHTHRPHTVVPMDDATQEYKEKLQKCLEPLEQKLQEITCCKASEEKKPGELKRLVESRRQQILKEFEELHRRLDEEQQTLLSRLEEEEQDILQRLRENAAHLGDRRRDLAHLAAEVEGKCLQSGFEMLKDVKSTLEK------------------------------CEKVKTMEVTSVSIELEKNFSNFPRQYFALRKILKQLIADVTLDPETAHPNLVLSEDRKSVKFVETRLRDLPDTPQRFTFYPCVLATEGFTSGRHYWEVEVGDKTHWAVGVCRDSVSRKGELTPLPETGYWRVRLWNGDKYAATTTPFTPLHIKVKPKRVGIFLDYEAGTLSFYNVTDRSHIYTFTDTFTEKLWPLFYPGIRAGRKNAAPLTIRPPTDWE", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9HCM9-1", "uniprot_id": "TRI39_HUMAN", "id": "Q9HCM9-1", "name": "E3 ubiquitin-protein ligase TRIM39", "aln": "MAETSLLEAGASAASTAAALENLQVEASCSVCLEYLKEPVIIECGHNFCKACITRWWEDLERDFPCPVCRKTSRYRSLRPNRQLGSMVEIAKQLQAVKRKIRDESLCPQHHEALSLFCYEDQEAVCLICAISHTHRAHTVVPLDDATQEYKEKLQKCLEPLEQKLQEITRCKSSEEKKPGELKRLVESRRQQILREFEELHRRLDEEQQVLLSRLEEEEQDILQRLRENAAHLGDKRRDLAHLAAEVEGKCLQSGFEMLKDVKSTLEKNIPRKFGGSLSTICPRDHKALLGLVKEINRCEKVKTMEVTSVSIELEKNFSNFPRQYFALRKILKQLIADVTLDPETAHPNLVLSEDRKSVKFVETRLRDLPDTPRRFTFYPCVLATEGFTSGRHYWEVEVGDKTHWAVGVCRDSVSRKGELTPLPETGYWRVRLWNGDKYAATTTPFTPLHIKVKPKRVGIFLDYEAGTLSFYNVTDRSHIYTFTDTFTEKLWPLFYPGIRAGRKNAAPLTIRPPTDWE", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "***********************************************************************************************:***********.****.***********************.*****:************************** **:***:*****************:**************.*************************:******************************** *********************:*****************************************************:************************************************************************************************************************************************", "identical_positions": 475, "similar_positions": 12, "identity": "91.7%" }, { "cls_id": "homologset.agr.MGI:1890662", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q920G2-1", "uniprot_id": "NHRF2_RAT", "id": "Q920G2-1", "name": "Na(+)/H(+) exchange regulatory cofactor NHE-RF2", "aln": "MAAPESLRPRLCRLVRGEQGYGFHLHGEKGRRGQFIRRVEPGSPAEAAALRAGDRLVEVNGVNVEGETHHQVVHRIKAVEGQTQLLVVDKETDEELCRRQLTCTEEMAHRGLPPAHNPWEPKPDWACSGSLGSDTGHKDVNGPPRELRPRLCHLRRGPQGYGFNLHSDKSRPGQYIRSVDPGSPASLSGLRAQDRLIEVNGQNVEGLRHAEVVARIKAQEDEARLLVVDPETDEHFKRLRVVPTEDHVEGPLPSPVTNGTSLAQLNGGSVCSSRSDLPGSEKDNEDGSAWKRDPFQESGLHLSPTAAEAKEKARATRVNKRAPQMDWNRKREIFSNF", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9JHL1-1", "uniprot_id": "NHRF2_MOUSE", "id": "Q9JHL1-1", "name": "Na(+)/H(+) exchange regulatory cofactor NHE-RF2", "aln": "MAAPESLRPRLCRLVRGEQGYGFHLHGEKGRRGQFIRRVEPGSPAEAAALRAGDRLVEVNGVNVEGETHHQVVQRIKAVEGQTQLLVVDKETDEELCRRQLTCTEEMAHRGLPPAHNPWEPKPDWACSGSLGSDTGQKDVNGPPRELRPRLCHLRRGPQGYGFNLHSDKSRPGQYIRSVDPGSPASHSGLRAQDRLIEVNGQNVEGLRHAEVVARIKAQEDEARLLVVDPETDEHFKRLRVVPTEEHVEGPLPSPVTNGTSPAQLNGGSVCSSRSDLPGSEKDNEDGSTWKRDPFQESGLHLSPTAAEAKEKARATRVNKRAPQMDWNRKREIFSNF", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q15599-1", "uniprot_id": "NHRF2_HUMAN", "id": "Q15599-1", "name": "Na(+)/H(+) exchange regulatory cofactor NHE-RF2", "aln": "MAAPEPLRPRLCRLVRGEQGYGFHLHGEKGRRGQFIRRVEPGSPAEAAALRAGDRLVEVNGVNVEGETHHQVVQRIKAVEGQTRLLVVDQETDEELRRRQLTCTEEMAQRGLPPAHDPWEPKPDWAHTGSHSSEAGKKDVSGPLRELRPRLCHLRKGPQGYGFNLHSDKSRPGQYIRSVDPGSPAARSGLRAQDRLIEVNGQNVEGLRHAEVVASIKAREDEARLLVVDPETDEHFKRLRVTPTEEHVEGPLPSPVTNGTSPAQLNGGSACSSRSDLPGSDKDTEDGSAWKQDPFQESGLHLSPTAAEAKEKARAMRVNKRAPQMDWNRKREIFSNF", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*****.*******************************************************************:*********:*****:****** ***********:*******:********* :** .*::*:***.** ***********:*****************************: *************************** ***:**********************.***:*************** *******.**********:**.****:**:*********************** *********************", "identical_positions": 307, "similar_positions": 22, "identity": "91.1%" }, { "cls_id": "homologset.agr.MGI:1890663", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9QYZ8-1", "uniprot_id": "DKK2_MOUSE", "id": "Q9QYZ8-1", "name": "Dickkopf-related protein 2", "aln": "MAALMRVKDSSRCLLLLAAVLMVESSQLGSSRAKLNSIKSSLGGETPAQSANRSAGMNQGLAFGGSKKGKSLGQAYPCSSDKECEVGRYCHSPHQGSSACMLCRRKKKRCHRDGMCCPGTRCNNGICIPVTESILTPHIPALDGTRHRDRNHGHYSNHDLGWQNLGRPHSKMPHIKGHEGDPCLRSSDCIDGFCCARHFWTKICKPVLHQGEVCTKQRKKGSHGLEIFQRCDCAKGLSCKVWKDATYSSKARLHVCQKI", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D3ZN48-1", "uniprot_id": "D3ZN48_RAT", "id": "D3ZN48-1", "name": "", "aln": "MAALMRVKDSSRCLLLLAAVLMVESSQLSSSRAKLNSIKSSLGGETPAQAANRSAGMNQGLAFGGSKKGKSLGQAYPCSSDKECEVGRYCHSPHQGSSACMVCRRKKKRCHRDGMCCPGTRCNNGICIPVTESILTPHIPALDGTRHRDRNHGHYSNHDLGWQNLGRPHSKMPHIKGHEGDPCLRSSDCIDGFCCARHFWTKICKPVLHQGEVCTKQRKKGSHGLEIFQRCDCAKGLSCKVWKDATYSSKARLHVCQKI", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9UBU2-1", "uniprot_id": "DKK2_HUMAN", "id": "Q9UBU2-1", "name": "Dickkopf-related protein 2", "aln": "MAALMRSKDSSCCLLLLAAVLMVESSQIGSSRAKLNSIKSSLGGETPGQAANRSAGMYQGLAFGGSKKGKNLGQAYPCSSDKECEVGRYCHSPHQGSSACMVCRRKKKRCHRDGMCCPSTRCNNGICIPVTESILTPHIPALDGTRHRDRNHGHYSNHDLGWQNLGRPHTKMSHIKGHEGDPCLRSSDCIEGFCCARHFWTKICKPVLHQGEVCTKQRKKGSHGLEIFQRCDCAKGLSCKVWKDATYSSKARLHVCQKI", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "****** **** ***************:.******************.*:******* ************.******************************:****************.**************************************************:**.*****************:********************************************************************", "identical_positions": 246, "similar_positions": 10, "identity": "94.98%" }, { "cls_id": "homologset.agr.MGI:1890682", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8VD58-1", "uniprot_id": "EVI2B_MOUSE", "id": "Q8VD58-1", "name": "Protein EVI2B", "aln": "MEFKYLVFIVLCQYLDNTFFSETEAITTEQQSLSTLITP-SLYVTTDSQNTAGNALSQTTRFKNISSGQQASPAQITPEQATPAVYVSSSPLTYNITRQAESAV----NNSLPQTSPSGFTLTNQ-PSPSTYNSTGQPPKHLVYTSTQQPPSPAPTSSGKPEVESTHNQPTKSTPTIYLQRDTPPPPPPPLTSEPPSGKGTAHKNNHNAIAAILIGTIIISMLVAILMIILWKYLRKPVLNDQNWAGRSPFADGETPEMCMDNIRESEASTKRASVVSLMTWKPSKSTLLADDLEVKLFESSEHINDTSNLKTDNVEVQINGLSEDSADGSTVGTAVSS-DDADLALPPPLLDLD---ENLPNKPTVTVVSPLPNDSINPQPSPDGLNQVCEEQHSKIQEPFPPPPDSFNVPLSAGDFINNQE-SAHEAQCQEFSTP-DLHPDLTDSLPPPPTELL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D3ZM19-1", "uniprot_id": "D3ZM19_RAT", "id": "D3ZM19-1", "name": "", "aln": "MEFRYLVFMLLCQYLNSTFSSETEATTAEHRPRSTLPTPLAVHVTNDSQNTGGNTLSQTTQFNNISSGQQVPPAQTTPQQATP---------------------------SIPQTSLSGFTLTNQ-LSSSAHNSTRQPPKPLAYTSTQQPPSTAPTSSAKPVLHTTGNRPTKSTPTIYLPRDTPPPP--PLTSEPTTGKGTAHKNNHNAIAAILIGTIIICMLVAILMIILWKYLRKPVLNDQNWAGRSPFADGETPEMCMDNIRESEVSTKRTSVVSLMPWKPSKSTLLADDLEVKLFESSEHINDTNNLKTENGKDQMHGLSEDSADGSTVGTAVSSSDDADLPLPPPLLDLD---ENLSDKPTMIVVPPLPNDSTNLQPPPDGLNQVCEDHHSQINEPFSPPPDSFSVPLSE-DFVSIQE-STREAQCQEFSAP-DLNQDLMDSLPPPPPELL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P34910-1", "uniprot_id": "EVI2B_HUMAN", "id": "P34910-1", "name": "Protein EVI2B", "aln": "MDPKYFILILFCGHLNNTFFSKTETITTEKQSQPTLFTSSMSQVLANSQNTTGNPLGQPTQFSDTFSGQSISPAKVTAGQPTPAVYTSSEKPEAHTSAGQPLAYNTKQPTPIANTSSQQAVFTSARQLPSARTSTTQPPKSFVYTFTQQSSSVQIPSRKQITVHNPSTQPTSTVKNS--PRSTP-----GFILDTTSNKQTPQKNNYNSIAAILIGVLLTSMLVAIIIIVLWKCLRKPVLNDQNWAGRSPFADGETPDICMDNIRENEISTKRTSIISLTPWKPSKSTLLADDLEIKLFESSENIEDSNNPKTEKIKDQVNGTSEDSADGSTVGTAVSSSDDADLPPPPPLLDLEGQESNQSDKPTMTIVSPLPNDSTSLPPSLDCLNQDCGDHKSEIIQSFPP-LDSLNLPLPPVDFMKNQEDSNLEIQCQEFSIPPNSDQDLNESLPPPPAELL", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*: :*::::::* :*:.** *:**: *:*::. .** *. * :**** **.*.*.*:*.: ***. .**: *. *.** .:.:** . .:*. .*: .** **** :.** ***..* .* : :... .:**.:. . *.** : :..:.* *.:***:*:*******.:: .*****::*:*** ***********************::*******.* ****:*::** .**************:*******:*:*:.* **:: : *::* **************** *****. *******: .* .:***: :*.****** . *. * *** * :::*:* :.*.* **:.:**. **:. ** * * ****** * : . ** :******.***", "identical_positions": 221, "similar_positions": 120, "identity": "48.46%" }, { "cls_id": "homologset.agr.MGI:1890695", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q99P75-1", "uniprot_id": "RAB9A_RAT", "id": "Q99P75-1", "name": "Ras-related protein Rab-9A", "aln": "---MAG--KSSLFKIILLGDGGVGKSSLMNRYVTNKFDSQLFHTIGVEFLNKDLEVDGHFVTMQIWDTAGQERFRSLRTPFYRGSDCCLLTFSVDDSQSFQNLSNWKKEFIYYADVKEPESFPFVILGNKTDIKE--RQVSTEEAQAWCKDNGDYPYFETSAKDSTNVAAAFEEAVR--RILATEDRSDHLIQTDTVNLHR--KPKPNSSCC---------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9R0M6-1", "uniprot_id": "RAB9A_MOUSE", "id": "Q9R0M6-1", "name": "Ras-related protein Rab-9A", "aln": "---MAG--KSSLFKIILLGDGGVGKSSLMNRYVTNKFDSQLFHTIGVEFLNKDLEVDGHFVTMQIWDTAGQERFRSLRTPFYRGSDCCLLTFSVDDSQSFQNLSNWKKEFIYYADVKEPESFPFVILGNKTDIKE--RQVSTEEAQAWCKDNGDYPYFETSAKDSTNVAAAFEEAVR--RILATEDRSEHLIQTDTVNLHR--KPKPNSSCC---------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P51151-1", "uniprot_id": "RAB9A_HUMAN", "id": "P51151-1", "name": "Ras-related protein Rab-9A", "aln": "---MAG--KSSLFKVILLGDGGVGKSSLMNRYVTNKFDTQLFHTIGVEFLNKDLEVDGHFVTMQIWDTAGQERFRSLRTPFYRGSDCCLLTFSVDDSQSFQNLSNWKKEFIYYADVKEPESFPFVILGNKIDISE--RQVSTEEAQAWCRDNGDYPYFETSAKDATNVAAAFEEAVR--RVLATEDRSDHLIQTDTVNLHR--KPKPSSSCC---------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VIW6-1", "uniprot_id": "Q9VIW6_DROME", "id": "Q9VIW6-1", "name": "small monomeric GTPase", "aln": "MTNMRPPQKSKLLKVVILGDGGVGKSALLTRFVANRYEENNFHTIGVEFMNKDIVVDGERYTLQIWDTAGQERFRALRTPFYRGSDICLLCYALDDRDSLKGLGVWRNEFLNYADVDQ-DKFPFIVVGNKNDIPAQKRQVSSDAVQQWCAEQKVACHIETSSKAATNVTDAFVLGLRQWRHMECVAEAELRQHGDTIDLTRPIRLVQRRICCTGGGGGGGGVGQDADGDDAAMHSPGKKVFGQKRNASKAPATNYRL", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * **.*:*:::*********:*:.*:*:*::: : ********:***: ***. *:************:********** *** :::** :*::.*. *::**: ****.: :.***:::*** ** ****:: .* ** :: ::***:* :***: ** .:* * : .:: : **::* * : ** ", "identical_positions": 101, "similar_positions": 57, "identity": "39.3%" }, { "cls_id": "homologset.agr.MGI:1890752", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "B8JJZ7-1", "uniprot_id": "B8JJZ7_MOUSE", "id": "B8JJZ7-1", "name": "", "aln": "MEPVTFEDVAVNFTLGEWALLDSYQKELYRDVMKETFSNLISIGKSEEDNIEDYQNIRRNLSTLMVEGFYEFERGIQYREMHQQIQEHIVNKYIPPGIVVYENSASKNDVIGLSQSDVHLRLLTVEKPYEYQKCMEKPIKHKKYWKDLAYSESFLAHENPPKEKPYGNKQSNDPCRSLTSDQDYETTHTGDNLHEYKQFETAIMTCSYGQSYERIQTGEKPFVCKQCGEAFVNSSHLIKHYKIHTREKTFACKYCGKAFIHPRACYNHERTHTGDRPYVCKQCGKACIHSYHLLQHERSHTREKLYACKQCGKVFGRSSYLRKHERIHTGEKPYLCKHCGKAFSDPTTRNNHERTHTGEKHYVCKQCGKAFIRSSQLLIHERIHTGEKPYSCKHCGKAFTYSSACYIHERIHTGEKPYVCKQCGKAFTCSTYLHKHERIHTGEKPYSCKQCGKAFIQHRACYNHERIHTGEKPYVCVQCGHAFTFSKSLQIHERNHTGEKPYVCKQCGKAFTCSTYLHQHERTHSEKKSSG", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8I5ZS44-1", "uniprot_id": "A0A8I5ZS44_RAT", "id": "A0A8I5ZS44-1", "name": "", "aln": "MEPVTFEDVAVNFTLGEWALLDSYQKELYRDVMKETFSNLISIGKTEEENIEDYQNIRRNLSTHVVEGFYEFERGIQYKETHQHIQEHAVHKYMPPGIVVYENIACENGVIDLSQSDVHPRVLTVEKSDERQKCTEKPVQHKKCWKDFVYSESFLTHEKPSREKPYGNEQFNDPCGSLTSYQGYETTHNGDNLREYKQLETALMTCSYVQSYERIQSGDKPFVCKQCGEAFVNSSHLIKHYKIHTREKTFACKYCGKAFIHPRACYNHERTHTGDRPYVCKQCGKACIHSYHLLQHERSHTREKLYACKQCGKVFGRSSYLRKHERIHTGEKPYLCKHCGKAFSDPTTRNNHERTHTGEKHYVCKQCGKAFIRSSQLLIHERIHTGEKPYSCKHCGKAFTYSSACYIHERIHTGEKPYVCKQCGKAFTCSTYLHKHERIHTGEKPYSCKQCGKAFIQHRACYNHERIHTGEKPYVCVQCGHAFTFSKSLQIHERNHTGEKPYVCKQCGKAFTCSTYLHQHERTHSEKKSNG", "tax_id": 10116, "tax_name": "Rat" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*********************************************:**:************** :*************:* **:**** *:**:********* *.:*.**.******* *:*****. * *** ***::*** ***:.******:**:*.:******:* **** **** *.*****.****:****:***:***** *******:*:**********************************************************************************************************************************************************************************************************************************************************************************************************************.*", "identical_positions": 488, "similar_positions": 30, "identity": "91.9%" }, { "cls_id": "homologset.agr.MGI:1890753", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A0G2JT46-1", "uniprot_id": "A0A0G2JT46_RAT", "id": "A0A0G2JT46-1", "name": "Zinc finger protein 545", "aln": "MARVSVMFSDVSVVFSKEEWDCLDLDQRTLYRDVMMENYHNVLSLAGCFISKPDVISLLEQGKEPWK-----RRRCPDSGVKDETHQLFSENGVYAVSLSQWKIMERIGNSGLKSLLLKHEWASRRRQERQEGSREGYLSQVKHTSERVSSSEKCT-LTTRQRIPSVEKPYECDACGKAFRVRQQLTFHHRIHTGEKPYECKECGMAFRQTAHLTRHQRLHSGEKLYECKECGQAFIYGPDLRAHQKLHTGEKPYACKECGKAFRVRGQLTLHQRIHTGEKPYVCKECGKAFRQYAHLTRHQKLNVADRLYACKECGKDFLCGSGLRVHHKLHTGEKPYECKDCGKAFRVRQQLTLHQRIHTGEKPYECNECGKTFSRGYHLILHHRIHTGEKPYECKECWKAFSRYSQLISHQSIHIGVKPYDCKECGKAFRLLSQLTQHQSIHAGEKPYTCKECGKSFRLRQKLTLHQSIHTGEKPFECKECRKAFRLNSSLIQHLRIHSGEKPYECKECKKAFRQHSHLTHHLKVHSVQV", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q6P9Y7-1", "uniprot_id": "ZFP82_MOUSE", "id": "Q6P9Y7-1", "name": "Zinc finger protein 82", "aln": "MARVSVVFSDVSIAFSQEEWESLDLEQRNLYKDVMMENYHNVASLG-CFISKPDVISLLEQGKEPWKVVRQ-RKPCPDSETKDETNQVFSENGIYEMNLSQWKIMERIGNSGLKSLLLKNGWESRRKQERQEDPQEGYLSQVRHTSERVSSYEKRA-LTTRQRIHFVEKPYECNECGKAFRVRQQLTFHHRIHTGEKPYECKECGMAFRQTAHLTRHQRLHSGEKLYECKECGQAFIYGPELRAHQKLHTGEKPYTCRECGKAFRVRGQLTLHQRIHTGEKPYVCQECGKAFRQLAHLTRHQKLNVVDRLYECKECGKDFLCGSGLRVHHKLHTGEKPYECKDCGKAFRVRQQLTLHQRSHTGEKPYECTECGKTFSRGYHLILHHRIHTGEKPYECKECWKAFSRYSQLISHQSIHIGVKPYDCKDCGKAFRLLSQLTQHQSVHAGEKPYSCKECGKSFRLRQKLALHQSIHTGEKPFECKECRKAFRLNSSLIQHLRIHSGEKPYECKECKKAFRQHSHLTHHLKVHTVKV", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8N141-1", "uniprot_id": "ZFP82_HUMAN", "id": "Q8N141-1", "name": "Zinc finger protein 82 homolog", "aln": "MALRSVMFSDVSIDFSPEEWEYLDLEQKDLYRDVMLENYSNLVSLG-CFISKPDVISSLEQGKEPWKVVRKGRRQYPDLETKYETKKLSLENDIYEINLSQWKIMERIENHGLKGLILKNDWESTGKIEGQERPQEGYFSSVKMPSEKVSSYQKRTSVTPHQRLHFVDKPYECKECGKAFRVRQQLTFHHRIHTGEKPYECKECGMAFRQTAHLTRHQRLHSGEKLYECKECGEAFICGADLRVHQKMHIGEKPYECKECGKAFRVRGQLTLHQRIHTGEKPYVCKECGKAFRQYAHLTRHQKLNSADRLYECKECGKAFLCGSGLRVHHKLHTGEKPYECKECGKAFRVRQQLTLHQRIHTGEKPYECKECGKTFSRGYHLILHHRIHTGEKPYECKECWKAFSRYSQLISHQSIHIGVKPYDCKECGKAFRLLSQLTQHQSIHIGEKPYKCKECGKAFRLRQKLTLHQSIHTGEKPFECKECRKAFRLNSSLIQHLRIHSGEKPYECKECKKAFRQHSHLTHHLKIHNVKI", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "** **:*****: ** ***: ***:*: **:***:*** *: **. ********** ********* *: ** .* **::: **.:* :.********** * ***.*:**: * * : * ** .:***:*.*: .**:*** :* : :*.:**: *:*****. **********************************************************:*** *.:**.***:* ***** *:***************************:******** ********** .**** ****** ***********************:**************** *********.********************************************************:****************:* *****.******:*******:************************************************************:*.*::", "identical_positions": 429, "similar_positions": 56, "identity": "80.49%" }, { "cls_id": "homologset.agr.MGI:1890773", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9QXQ0-1", "uniprot_id": "ACTN4_RAT", "id": "Q9QXQ0-1", "name": "Alpha-actinin-4", "aln": "MVDYHAANQAYQYGPSSGG-NGTGGGGGMGDYMAQEDDWDRDLLLDPAWEKQQRKTFTAWCNSHLRKAGTQIENIDEDFRDGLKLMLLLEVISGERLPKPERGKMRVHKINNVNKALDFIASKGVKLVSIGAEEIVDGNAKMTLGMIWTIILRFAIQDISVEETSAKEGLLLWCQRKTAPYKNVNVQNFHISWKDGLAFNALIHRHRPELIEYDKLRKDDPVTNLNNAFEVAEKYLDIPKMLDAEDIVNTARPDEKAIMTYVSSFYHAFSGAQKA----------------------ETAANRICKVLAVNQENEHLMEDYERLASDLLEWIRRTIPWLEDRVPQKTIQEMQQKLEDFRDYRRVHKPPKVQEKCQLEINFNTLQTKLRLSNRPAFMPSEGRMVSDINNGWQHLEQAEKGYEEWLLNEIRRLERLDHLAEKFRQKASIHEAWTDGKEAMLKHRDYETATLSDIKALIRKHEAFESDLAAHQDRVEQIAAIAQELNELDYYDSHNVNTRCQKICDQWDNLGSLTHSRREALEKTEKQLETIDQLHLEYAKRAAPFNNWMESAMEDLQDMFIVHTIEEIEGLISAHDQFKSTLPDADREREAILAIHKEAQRIAESNHIKLSGSNPYTSVTPQIINSKWEKVQQLVPKRDHALLEEQSKQQSNEHLRRQFASQANMVGPWIQTKMEEIGRISIEMNGTLEDQLSHLKQYERSIVDYKPNLDLLEQQHQLIQEALIFDNKHTNYTMEHLRVGWEQLLTTIARTINEVENQILTRDAKGISQEQMQEFRASFNHFDKDHGGALGPEEFKACLISLGYDVENDRQ----------------------GDAEFNRIMSVVDPNHSGLVTFQAFIDFMSRETTDTDTADQVIASFKVLAGDKNFITAEELRRELPPDQAEYCIARMAPYQGPDAAPGALDYKSFSTALYGESDL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P57780-1", "uniprot_id": "ACTN4_MOUSE", "id": "P57780-1", "name": "Alpha-actinin-4", "aln": "MVDYHAANQAYQYGPNSGGGNGAGGGGSMGDYMAQEDDWDRDLLLDPAWEKQQRKTFTAWCNSHLRKAGTQIENIDEDFRDGLKLMLLLEVISGERLPKPERGKMRVHKINNVNKALDFIASKGVKLVSIGAEEIVDGNAKMTLGMIWTIILRFAIQDISVEETSAKEGLLLWCQRKTAPYKNVNVQNFHISWKDGLAFNALIHRHRPELIEYDKLRKDDPVTNLNNAFEVAEKYLDIPKMLDAEDIVNTARPDEKAIMTYVSSFYHAFSGAQKA----------------------ETAANRICKVLAVNQENEHLMEDYERLASDLLEWIRRTIPWLEDRVPQKTIQEMQQKLEDFRDYRRVHKPPKVQEKCQLEINFNTLQTKLRLSNRPAFMPSEGRMVSDINNGWQHLEQAEKGYEEWLLNEIRRLERLDHLAEKFRQKASIHEAWTDGKEAMLKQRDYETATLSDIKALIRKHEAFESDLAAHQDRVEQIAAIAQELNELDYYDSHNVNTRCQKICDQWDNLGSLTHSRREALEKTEKQLETIDQLHLEYAKRAAPFNNWMESAMEDLQDMFIVHTIEEIEGLISAHDQFKSTLPDADREREAILAIHKEAQRIAESNHIKLSGSNPYTTVTPQIINSKWEKVQQLVPKRDHALLEEQSKQQSNEHLRRQFASQANMVGPWIQTKMEEIGRISIEMNGTLEDQLSHLKQYERSIVDYKPSLDLLEQQHQLIQEALIFDNKHTNYTMEHIRVGWEQLLTTIARTINEVENQILTRDAKGISQEQMQEFRASFNHFDKDHGGALGPEEFKACLISLGYDVENDRQ----------------------GDAEFNRIMSVVDPNHSGLVTFQAFIDFMSRETTDTDTADQVIASFKVLAGDKNFITAEELRRELPPDQAEYCIARMAPYQGPDAAPGALDYKSFSTALYGESDL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O43707-1", "uniprot_id": "ACTN4_HUMAN", "id": "O43707-1", "name": "Alpha-actinin-4", "aln": "MVDYHAANQSYQYGPSSAG-NGAGGGGSMGDYMAQEDDWDRDLLLDPAWEKQQRKTFTAWCNSHLRKAGTQIENIDEDFRDGLKLMLLLEVISGERLPKPERGKMRVHKINNVNKALDFIASKGVKLVSIGAEEIVDGNAKMTLGMIWTIILRFAIQDISVEETSAKEGLLLWCQRKTAPYKNVNVQNFHISWKDGLAFNALIHRHRPELIEYDKLRKDDPVTNLNNAFEVAEKYLDIPKMLDAEDIVNTARPDEKAIMTYVSSFYHAFSGAQKA----------------------ETAANRICKVLAVNQENEHLMEDYEKLASDLLEWIRRTIPWLEDRVPQKTIQEMQQKLEDFRDYRRVHKPPKVQEKCQLEINFNTLQTKLRLSNRPAFMPSEGKMVSDINNGWQHLEQAEKGYEEWLLNEIRRLERLDHLAEKFRQKASIHEAWTDGKEAMLKHRDYETATLSDIKALIRKHEAFESDLAAHQDRVEQIAAIAQELNELDYYDSHNVNTRCQKICDQWDALGSLTHSRREALEKTEKQLEAIDQLHLEYAKRAAPFNNWMESAMEDLQDMFIVHTIEEIEGLISAHDQFKSTLPDADREREAILAIHKEAQRIAESNHIKLSGSNPYTTVTPQIINSKWEKVQQLVPKRDHALLEEQSKQQSNEHLRRQFASQANVVGPWIQTKMEEIGRISIEMNGTLEDQLSHLKQYERSIVDYKPNLDLLEQQHQLIQEALIFDNKHTNYTMEHIRVGWEQLLTTIARTINEVENQILTRDAKGISQEQMQEFRASFNHFDKDHGGALGPEEFKACLISLGYDVENDRQ----------------------GEAEFNRIMSLVDPNHSGLVTFQAFIDFMSRETTDTDTADQVIASFKVLAGDKNFITAEELRRELPPDQAEYCIARMAPYQGPDAVPGALDYKSFSTALYGESDL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9QL95-1", "uniprot_id": "A0A8M9QL95_DANRE", "id": "A0A8M9QL95-1", "name": "", "aln": "MVDYHAVNNQGQYS-----------AGGPPTYMEQENDWDRDLLLDPAWEKQQRKTFTAWCNSHLRKAGTQIENIEEDFRDGLKLMLLLEVISGERLPKPERGKMRVHKINNVNKALDFIASKGVKLVSIGAEEIVDGNAKMTLGMIWTIILRFAIQDISVEETSAKEGLLLWCQRKTAPYKNVNVQNFHISWKDGLAFNALIHRHRPELIDYDKLRKDDPVTNLNNAFEVAERYLDIPKMLDAEDIVNTARPDEKAIMTYVSSFYHAFSGAQKA----------------------ETAANRICKVLAVNQENEHLMEDYEKLASDLLEWIRRTIPWLENRAPEKTMAEMQQKLEDFRDYRRVHKPPKVQEKCQLEINFNTLQTKLRLSNRPAFMPSEGRMVSDINGAWHKLEGAEKGYEEWLLNEIRRLERLDHLAEKFRQKAAIHEGWTDGKEAMLTQKDYETASLSEIKALLKKHEAFESDLAAHQDRVEQIAAIAQELNELDYYDSPSVNARCQKICEQWDALGSLTQNRRESLERTEKQLESIDELYLEYAKRAAPFNNWMEGAMEDLQDMFIVHNIDEIQGLITAHEQFKSTLPEANKEREAIQAIQAEVQKIANYNGIKLAGNNPYTTITPQSIDKKWEKVQQLVPQRDQALQEELTRQQSNDHLRRQFANQANMIGPWIQNKMEEIGRISIEMNGTLEDQLTHLSQYEQSIIEYKPNIDQLEGDHQLIQEALIFDNKYTAYTMEHLRVGWEQLLTTIARTINEIENQVLTRDAKGISQEQLHEYRTSFNHFDKDHSGLLQSEEFKACLISLGYDVENDKQKRTGIMDSDDFRALLISTGNSLGDAEFARIMGIVDPNNSGAVTFQAFIDFMSRETTDTDTADQVIASFKILAGDKNYITAEELRRELPPDQAEYCIARMAPYSGPDAVAGALDYMSFSTALYGESDL", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P18091-3", "uniprot_id": "ACTN_DROME", "id": "P18091-3", "name": "Alpha-actinin, sarcomeric", "aln": "MMMENGLSMEYGDG-----------------YMEQEEEWEREGLLDPAWEKQQKKTFTAWCNSHLRKAGTAIDNIEEDFRNGLKLMLLLEVISGETLPKPDRGKMRFHKIANVNKALDFIASKGVHLVSIGAEEIVDGNLKMTLGMIWTIILRFAIQDISVEEMTAKEGLLLWCQRKTAPYKNVNVQNFHLSFKDGLAFCALIHRHRPDLIDYAKLSKDNPLENLNTAFDVAEKYLDIPRMLDPDDLINTPKPDERAIMTYVSCYYHAFQGAQQVGNVTHVPEPTRQYTYVPNNYNAETAANRICKVLKVNQENERLMEEYERLASDLLEWIRRTMPWLNSRQADNSLAGVQKKLEEYRTYRRKHKPPRVEQKAKLETNFNTLQTKLRLSNRPAYLPTEGKTVSDISNSWKGLELAEKAFEEWLLAETMRLERLEHLAQKFKHKADAHEDWTRGKEEMLQSQDFRQCKLNELKALKKKHEAFESDLAAHQDRVEQIAAIAQELNTLEYHDCVSVNARCQRICDQWDRLGALTQRRRTALDEAERILEKIDILHLEFAKRAAPFNNWLDGTREDLVDMFIVHTMEEIQGLIQAHDQFKATLGEADKEFNLIVNLVREVESIVKQHQIPGGLENPYTTLTANDMTRKWSDVRQLVPQRDQTLANELRKQQNNEMLRRQFAEKANIVGPWIERQMDAVTAIGMGLQGSLEDQLHRLKEYEQAVYAYKPNIEELEKIHQAVQESMIFENRYTNYTMETLRVGWEQLLTSINRNINEVENQILTRDSKGISQEQLNEFRSSFNHFDKNRTGRLSPEEFKSCLVSLGYSIGKDRQ----------------------GDLDFQRILAVVDPNNTGYVHFDAFLDFMTRESTDTDTAEQVIDSFRILAADKPYILPDELRRELPPDQAEYCIQRMPPYKGPNGVPGALDYMSFSTALYGETDL", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*: :. . . ** **::*:*: **********:**************** *:**:****:************** ****:*****.*** **************:************* *********************** :*************************:*:****** ********:**:* ** **:*: ***.**:***:*****:***.:*::**.:***:*******.:****.***:. *********** ******:***:**:************:***:.* .:::: :*:***::* *** ****:*::*.:** ****************::*:**: ****...*: ** ***.:***** * *****:***:**::** ** ** *** ** :*:. ..*.::*** :*************************** *:*:*. .**:***:**:*** **:**: ** :*:.:*: ** ** *:**:**********::.: *** ******.::**:*** **:***:** :*::* : * : *.: *.: : * . .****::*.: : **..*:****:**::* :* :**.*: ******.:**::****: :*: : *.: ::*:***** :*.:**::: ***.:: ** ** :**::**:*::* **** :*********:* *.***:***:****:*******::*:*:*******:: * * .****:**:****.: :*:* *: :* **:.:****::* * *:**:***:**:******:*** **::**.** :* .:*************** **.**.**:...***** *********:**", "identical_positions": 588, "similar_positions": 207, "identity": "61.51%" }, { "cls_id": "homologset.agr.MGI:1890811", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q86SE8-1", "uniprot_id": "NPM2_HUMAN", "id": "Q86SE8-1", "name": "Nucleoplasmin-2", "aln": "MNLSSASSTEEKAVTT------------------VLWGCELSQERRTWTFRP----QLEGKQSCRLLLHTICLGEKAK-EEMHRVEILPPAN-QEDKKMQPVTIASLQASVLPMVSMVGVQLSPPVTFQLRAGSGPVFLSGQERYEASDLTWEEEEEEEGEEEEEEEEDDEDEDADISLEEQSPVKQVKRLVPQKQASVAKKKKLEKEEEE--IRASVRDKSPVKKAKATARAKKPGFKK", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q80W85-1", "uniprot_id": "NPM2_MOUSE", "id": "Q80W85-1", "name": "Nucleoplasmin-2", "aln": "MSRHSTSSVTETTAKN------------------MLWGSELNQEKQTCTFRG----QGEKKDSCKLLLSTICLGEKAK-EEVNRVEVLS----QEGRK-PPITIATLKASVLPMVTVSGIELSPPVTFRLRTGSGPVFLSGLECYETSDLTWEDDEEEE----EEEEEEDEDEDADISLEEI-PVKQVKRVAPQKQMSIAKKKKVEKEEDETVVRPSPQDKSPWKKEKSTPRAKKPVTKK", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "B0UYT8-1", "uniprot_id": "B0UYT8_DANRE", "id": "B0UYT8-1", "name": "", "aln": "MFANMTSSFDENDSATSFSLSELSTSSSVSDRACVHWGCVLSGSKTTAVFKA----ENDLLEN-QFFIKTICLSEDAG-DEMHIVAVCDG-----VGASKPLPIATLRH-CMPMISFPGLELIPPVTFKLCSGKGPVFVSAQHITLNPIEMIEEEEEEK-----QDEEEDEDG-------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q27415-1", "uniprot_id": "NLP_DROME", "id": "Q27415-1", "name": "Nucleoplasmin-like protein", "aln": "--------MAEES----------------------FYGVTLTAESDSVTWDV----DEDYARGQKLVIKQILLGAEAKENEFNVVEVNT------PKDSVQIPIAVLKAGETRAVNPDVEFYESKVTFKLIKGSGPVYIHGHNIKDDVEVVDMEEDDEE-----DDVAEDEEDEHPKKRAKIENAADGKNAKNNKKK-------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VAC4-1", "uniprot_id": "Q9VAC4_DROME", "id": "Q9VAC4-1", "name": "", "aln": "--------MESES----------------------FYGVTLSEKEAIAQFEVPDVPEEYIVHSHKLIIKQISLGPEAKTGEFNVVQAETNINDDGEKKTLKIPIAVLKVGETRSLRPNVEFPNGSVTFKLVQGSGPVHVCG---KVEMNFGEFDDGQIY-----EEYSDEEED---SELEFDEEAAPQTNGKSNKKK-------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . :* *. . : : . ::.: * *. .* *.: * :.** *: : ***:* *.***.: . :: : :: ::*: ", "identical_positions": 19, "similar_positions": 32, "identity": "7.92%" }, { "cls_id": "homologset.agr.MGI:1890816", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZQZ0-1", "uniprot_id": "D3ZQZ0_RAT", "id": "D3ZQZ0-1", "name": "Visual system homeobox 1", "aln": "MTGRDGLLDGRSRSRALAPGCPP------TGSRLRSFAINDLLGLEADL-PTPAEPGLRSNCEAPAEATG--PGPGPGLCGTCPARGALPLGLGLLCGFGAQPP-SATAARARCLLLADLRLLPPAGPEPAVAQSPVHPPPALGSQQRSENISTSDGDSPSEEKNDPKMSLTLGKRKKRRHRTVFTAHQLEELEKAFGEAHYPDVYAREMLAVKTELPEDRIQVWFQNRRAKWRKREKRWGGSSVMAEYGLYGAMVRHCIPLPDSVLNSADS-LQGSCAPWLL----GMHKKSTEMR-KPESEEKLAGLWELDHLRKGAKKDEDGPERGPGKASLNPEGSLEDVAIDLSSSSRQETKKMPSGSSTQGCTHAPGPQVLQPPQVGAS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q91V10-1", "uniprot_id": "VSX1_MOUSE", "id": "Q91V10-1", "name": "Visual system homeobox 1", "aln": "MTGRDGLSDARSRSRALAPGCPP------TGSRLRSFAINDLLGLEADL-PTPAEPGLRSNSGDPAEAIGSGPGPGPGLCGSCPARGALPLGLGLLCGFGAQPPSAAAAARARCLLLADLRLLPSAGPEPAVAQGPVHPPPALGSQQRSESVSTSDGDSPSEEKNDPKMSLILGKRKKRRHRTVFTAHQLEELEKAFGEAHYPDVYAREMLAAKTELPEDRIQVWFQNRRAKWRKREKRWGGSSVMAEYGLYGAMVRHCIPLPDSVLNSADS-LQGSCAPWLL----GMHKKSTGMR-KPESEDKLAGLWEFDHLKKGANKDEDGPERGPDETTQNPENSLEDVAIDLSSSSRQETKKMPPGSSTQ---------LPQPPQVGAS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9NZR4-1", "uniprot_id": "VSX1_HUMAN", "id": "Q9NZR4-1", "name": "Visual system homeobox 1", "aln": "MTGRDSLSDGRTSSRALVPGGSP------RGSRPRGFAITDLLGLEAEL-PAPAGPGQGSGCEGPAVAPC----PGPGLDGSSLARGALPLGLGLLCGFGTQPP---AAARAPCLLLADVPFLPPRGPEPAAPLAPSRPPPALGRQKRSDSVSTSDEDSQSEDRNDLKASPTLGKRKKRRHRTVFTAHQLEELEKAFSEAHYPDVYAREMLAVKTELPEDRIQVWFQNRRAKWRKREKRWGGSSVMAEYGLYGAMVRHCIPLPDSVLNSAEGGLLGSCAPWLL----GMHKKSMGMIRKPGSEDKLAGLWGSDHFKEGSSQSESGSQRGSDKVS--PENGLEDVAIDLSSSARQETKKVHPGAGAQGGSNSTALEGPQPGKVGAT", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "O42250-1", "uniprot_id": "VSX1_DANRE", "id": "O42250-1", "name": "Visual system homeobox 1", "aln": "MTGREEATDEKPKVKLYPSFGIDKSRLNGSGFRSKGFAITDLLGLESELQPHQSGPGAGPNGEGQSAAVG----------GFSFPGGSLPLGLGFLCSLAAQQP-----PGAPCFLPSHIPLLQSR-TESHFMQNLE--------QQRD---VYSDDDCLSGDRNDGKNSGNSQKRKKRRHRTVFTSHQLEELEKAFNEAHYPDVYAREMLAMKTELPEDRIQVWFQNRRAKWRKREKCWGRSSVMAEYGLYGAMVRHSIPLPESIINSAKSGMMGSCAPWLLGEPAGMHKKSMEIVKKAPGTPEST---HSDTYSEEHKGKDSDTTWSSGANG---ADDSEDMAIDLSSTSKQENKSTLKRSPPR--------TENSSDSENES", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "****: * :. : . * * :.***.******::* * : ** .. : * * . . *:******:**.:.:* * . * *:* :.: :* . .*. *:*. ** *. * ::** * * ************:**********.************** ************************* ** ****************.****:*::***.. : ******** ****** : *. . : : * : . .:... ... .. **:******:::**.*. : .: .. . . :", "identical_positions": 162, "similar_positions": 76, "identity": "42.08%" }, { "cls_id": "homologset.agr.MGI:1890889", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q99LY9-1", "uniprot_id": "NDUS5_MOUSE", "id": "Q99LY9-1", "name": "NADH dehydrogenase [ubiquinone] iron-sulfur protein 5", "aln": "MPFLDIQKKLGISLDRHFMFLSAEQPYKNAARCHAFEKEWIECAHGIGGTRAKKECKIEFDDFEECLLRYKTMRRMHDIKKQREKLMKEGKYTPPPHHSGREEPRP", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "B5DEL8-1", "uniprot_id": "B5DEL8_RAT", "id": "B5DEL8-1", "name": "NADH dehydrogenase [ubiquinone] iron-sulfur protein 5", "aln": "MPFLDVQKRLGISLDRHFIFLSAEQPYKNAARCHAFEKEWIECAHGIGATRAKKECKIEYEDFEECFLRFKTIRRMHEIKKQREKLMKEGKYTPPPHHLGKEEPRP", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O43920-1", "uniprot_id": "NDUS5_HUMAN", "id": "O43920-1", "name": "NADH dehydrogenase [ubiquinone] iron-sulfur protein 5", "aln": "MPFLDIQKRFGLNIDRWLTIQSGEQPYKMAGRCHAFEKEWIECAHGIGYTRAEKECKIEYDDFVECLLRQKTMRRAGTIRKQRDKLIKEGKYTPPPHHIGKGEPRP", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*****:**::*:.:** : : *.***** *.***************** ***:******::** **:** **:** *:***:**:*********** *: ****", "identical_positions": 75, "similar_positions": 19, "identity": "70.75%" }, { "cls_id": "homologset.agr.MGI:1890894", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q6PCU8-1", "uniprot_id": "NDUV3_RAT", "id": "Q6PCU8-1", "name": "NADH dehydrogenase [ubiquinone] flavoprotein 3, mitochondrial", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MAVSLLLRGGRIRALKAALLEAKVFRGELASTVP--------------------------LSTESENNKKAAG------------------------PTSKTESVFKEPTLV-PESSDTTTYKNLQHHEYNAFTFLDLNLDLSKFRLPQPSSGRESPRH", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8BK30-1", "uniprot_id": "NDUV3_MOUSE", "id": "Q8BK30-1", "name": "NADH dehydrogenase [ubiquinone] flavoprotein 3, mitochondrial", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MAVSLLLRGGRIRALKAVLLEARVFPGELVSVVR--------------------------LSTESEKSAKEKE------------------------LHPKTQSVLKE-----PEPTDTTTYKNLQHHDYNTYTFLDLNLDLSKFRLPQPSSGRESPRH", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P56181-1", "uniprot_id": "NDUV3_HUMAN", "id": "P56181-1", "name": "NADH dehydrogenase [ubiquinone] flavoprotein 3, mitochondrial", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MAAPCLLRQGRAGALKTMLQEAQVFRG-LASTVS--------------------------LSAESGKSEKGQP------------------------QNSKKQSPPKKPAPVPAEPFDNTTYKNLQHHDYSTYTFLDLNLELSKFRMPQPSSGRESPRH", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M3BCF6-1", "uniprot_id": "A0A8M3BCF6_DANRE", "id": "A0A8M3BCF6-1", "name": "", "aln": "MAMSLLRLGRLGSVKCLLRGGWSPPKTQFAAALCTKADVPPKTPKKGKASSKSKTIEADERASLLAYKPAVAFPSKLVATGFLSKDVALGESETAKAAFTTPANEKTTDSPPADTAAADVAVEEPKITEIPTTGKAPTEGERSKALDPDSEAKKDDEDTSSSSSSSSDSDSDSDDEEPKTEPPQQTGEKAEKKDSSVANEQVDLADKIAKPVSASFKEECVETVKSTPEVLAPSAKPVGSAETLVDPAPIVSSSATHAISAPSPKVSSSATEAISAPVPIVSSSETETISDPVPKVSTSATEAIPDPAPKVSSSATEAIPDPAPKVSSSATETIHDPAFKVSSSATQAIPEAPGESLNVGTPDIIADIPAKEVKTVPTEESIIKAEEAASVVPEVSTKASHLASPPEAPGDVAPKSEDLSAKAEAGAPSAPSEELVDPAPAAADAVEALAQTDVVETPEEQAPEKAPEPE-PEPFDNTTYKNLQHHNYNMYTFTDMDVEMAKYRLPQPSSGRPSPQH", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :... :: :*: * :: . .: * **::: . .: :: * .*. *.*********:*. :** *::::::*:*:******* **:*", "identical_positions": 33, "similar_positions": 36, "identity": "6.38%" }, { "cls_id": "homologset.agr.MGI:1890948", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D4A4J0-1", "uniprot_id": "D4A4J0_RAT", "id": "D4A4J0-1", "name": "FACT complex subunit", "aln": "-MAVTLDKDAYYRRVKRLYSNWRK----GEDEYASIDAIVVSVG-VDEEIVYAKSTALQTWLFGYELTDTIMVFCDDKIIFMASKKKVEFLKQIANTKGNENANGAPAITLLVREKNESNKSSFDKMIEAIKESKNGKKIGVFSKDKFPGEFMKSWS----DCLNKEGFDKVDISAVVAYTIAVKEDGELNLMKKAASITSEVFNKFFKERVMEIVDADEKVRHSKLAESVEKAIEEKKYLAGADPSTVEMCYP--------------PIIQSGGNYNLKFSVVSDKNHMH-FGAITCAMGIRFKSYCSNLVRTLMVDPTQEVQENYNFLLQLQEELLK-ELRHGVKICDVYNSVMDVVKKQKPELLNKITKNLGFGMGIEFREGSLVINSKNQY-KLKKGMVFSINLGFSDLTNKEGKKPEEKTYALFIGDTVLV--DEDGPATVLTSVKKKVKNVGIFLKNEDDEEEEEEK-----DEAEDLLGRGSRA-ALLTERTR-------NEMTAEEKRRAHQKELAAQLNEEAKRRLTEQKGEQQIQKARKSNVSYKNPSLMPKEPH-IREMKIYIDKKYETVIMPVFGIATPFHIATIKNISMSVEGDYTYLRINFYCPGSALGRNEGNIFPNPEATFVKEITYRASNMKAPGEQTVPALNLQNAFRIIKEVQKRYKTREAEEKEKEGIVKQDSLVINLNRSNPKLKDLYIRPNIAQKRMQGSLEAHVNGFRFTS--VRGDKVDILYNNIKHALFQPCDGEMIIVLHFHLKNAIMFGKKRHTDVQFYTEVGEITTDLG--------KHQHMHDRDDLYAEQMEREMRHKLKTAFKNFIEKVEALTKEELEFEVPFRDLGFNGAPYRSTCLLQPTSSALVNATEWPPFVVTLDEVELIHFERVQFHLKNFDMVIVYKDYSKKVTMINAIPVASLDPIKEWLNSCDLKYTEGVQSLNWTKIMKTIVDDPEGFFEQGGWSFLEPEGEGSDAEDGDSESEIEDETFNPSEDDYEEEEEDSDEDYSSEAEESDYSKESLGSEEESGKDWDELEEEARKADRESRYEEEEE--QSRSMSRKR-KASVHSSGRGS-----NRGSRHSSAPP-------KKKRK------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q920B9-1", "uniprot_id": "SP16H_MOUSE", "id": "Q920B9-1", "name": "FACT complex subunit SPT16", "aln": "-MAVTLDKDAYYRRVKRLYSNWRK----GEDEYASIDAIVVSVG-VDEEIVYAKSTALQTWLFGYELTDTIMVFCDDKIIFMASKKKVEFLKQIANTKGNENANGAPAITLLVREKNESNKSSFDKMIDAIKESKSGKKIGVFSKDKFPGEFMKSWS----DCLNKEGFDKVDISAVVAYTIAVKEDGELNLMKKAASITSEVFNKFFKERVMEIVDADEKVRHSKLAESVEKAIEEKKYLAGADPSTVEMCYP--------------PIIQSGGNYNLKFSVVSDKNHMH-FGAITCAMGIRFKSYCSNLVRTLMVDPTQEVQENYNFLLQLQEELLK-ELRHGVKICDVYNSVMDVVKKQKPELLNKITKNLGFGMGIEFREGSLVINSKNQY-KLKKGMVFSINLGFSDLTNKEGKKPEEKTYALFIGDTVLV--DEDGPATILTSVKKKVKNVGIFLKNEDDEEEEEEK-----DEAEDLLGRGSRA-ALLTERTR-------NEMTAEEKRRAHQKELAAQLNEEAKRRLTEQKGEQQIQKARKSNVSYKNPSLMPKEPH-IREMKIYIDKKYETVIMPVFGIATPFHIATIKNISMSVEGDYTYLRINFYCPGSALGRNEGNIFPNPEATFVKEITYRASNMKAPGEQTVPALNLQNAFRIIKEVQKRYKTREAEEKEKEGIVKQDSLVINLNRSNPKLKDLYIRPNIAQKRMQGSLEAHVNGFRFTS--VRGDKVDILYNNIKHALFQPCDGEMIIVLHFHLKNAVMFGKKRHTDVQFYTEVGEITTDLG--------KHQHMHDRDDLYAEQMEREMRHKLKTAFKNFIEKVEALTKEELEFEVPFRDLGFNGAPYRSTCLLQPTSSALVNATEWPPFVVTLDEVELIHFERVQFHLKNFDMVIVYKDYSKKVTMINAIPVASLDPIKEWLNSCDLKYTEGVQSLNWTKIMKTIVDDPEGFFEQGGWSFLEPEGEGSDAEDGDSESEIEDETFNPSEDDYEEEEEDSDEDYSSEAEESDYSKESLGSEEESGKDWDELEEEARKADRESRYEEEEE--QSRSMSRKR-KASVHSSGRGS-----NRGSRHSSAPP-------KKKRK------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9Y5B9-1", "uniprot_id": "SP16H_HUMAN", "id": "Q9Y5B9-1", "name": "FACT complex subunit SPT16", "aln": "-MAVTLDKDAYYRRVKRLYSNWRK----GEDEYANVDAIVVSVG-VDEEIVYAKSTALQTWLFGYELTDTIMVFCDDKIIFMASKKKVEFLKQIANTKGNENANGAPAITLLIREKNESNKSSFDKMIEAIKESKNGKKIGVFSKDKFPGEFMKSWN----DCLNKEGFDKIDISAVVAYTIAVKEDGELNLMKKAASITSEVFNKFFKERVMEIVDADEKVRHSKLAESVEKAIEEKKYLAGADPSTVEMCYP--------------PIIQSGGNYNLKFSVVSDKNHMH-FGAITCAMGIRFKSYCSNLVRTLMVDPSQEVQENYNFLLQLQEELLK-ELRHGVKICDVYNAVMDVVKKQKPELLNKITKNLGFGMGIEFREGSLVINSKNQY-KLKKGMVFSINLGFSDLTNKEGKKPEEKTYALFIGDTVLV--DEDGPATVLTSVKKKVKNVGIFLKNEDEEEEEEEK-----DEAEDLLGRGSRA-ALLTERTR-------NEMTAEEKRRAHQKELAAQLNEEAKRRLTEQKGEQQIQKARKSNVSYKNPSLMPKEPH-IREMKIYIDKKYETVIMPVFGIATPFHIATIKNISMSVEGDYTYLRINFYCPGSALGRNEGNIFPNPEATFVKEITYRASNIKAPGEQTVPALNLQNAFRIIKEVQKRYKTREAEEKEKEGIVKQDSLVINLNRSNPKLKDLYIRPNIAQKRMQGSLEAHVNGFRFTS--VRGDKVDILYNNIKHALFQPCDGEMIIVLHFHLKNAIMFGKKRHTDVQFYTEVGEITTDLG--------KHQHMHDRDDLYAEQMEREMRHKLKTAFKNFIEKVEALTKEELEFEVPFRDLGFNGAPYRSTCLLQPTSSALVNATEWPPFVVTLDEVELIHFERVQFHLKNFDMVIVYKDYSKKVTMINAIPVASLDPIKEWLNSCDLKYTEGVQSLNWTKIMKTIVDDPEGFFEQGGWSFLEPEGEGSDAEEGDSESEIEDETFNPSEDDYEEEEEDSDEDYSSEAEESDYSKESLGSEEESGKDWDELEEEARKADRESRYEEEEE--QSRSMSRKR-KASVHSSGRGS-----NRGSRHSSAPP-------KKKRK------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8IRG6-1", "uniprot_id": "SPT16_DROME", "id": "Q8IRG6-1", "name": "FACT complex subunit spt16", "aln": "MSSFVLDKEAFVRRVKRLYTEWRAPSIGHDDALRNLDCIMSIVG-VEEDVMYSKSMALQLWLLGYELTDTISVFCSDAVYFLTSKKKIEFLKQTQNIT----EEGFPEINLLVRDRTDKDQGNFEKLIKALQNSKKGKRLGVFAKDAYPGEFSEAWK----KSLTASKFEHVDISTIIAYLMCPKDESEINNIRKASLVSMDIFNKYLKDEIMDIIDSDRKVKHNKLSDGCEAAIGEKKYTSGLDPRLLDMAYP--------------PIIQSGGAYSLKFSAVADKNPLH-FGVIVCSLGARYKSYCSNISRTFLVNPTEAMQENYTFLVSVQEEILK-LLVPGTKLCDVYEKTLDFVKKEKPSMVDNLPKSFGFAMGLEFRENSIVIGPKCQA-LLKKNMVFNLHVGISNLTNPEATDKEGKNYALFIGDTVLV--GEQSPASVMTPSKKKIKNVGIFIKDDSDEEDVDDKKTAKEDQGTEILGRSKRN-AVLESKLR-------NEINTEEKRKEHQRELAQQLNERAKDRLARQGNSKEVEKVRKNTVSYKSISQMPREPE-VKELKLYVDKKYETVIMPVFGIQVPFHISTIKNISQSVEGEYTYLRINFFHPGATMGRNEGGLYPQPEATFVKEVTYRSSNVKEHGEVGAPSANLNNAFRLIKEVQKRFKTREAEEREKEDLVKQDTLILSQNKGNPKLKDLYIRPNIVTKRMTGSLEAHSNGFRYIS--VRGDKVDILYNNIKSAFFQPCDGEMIILLHFHLKYAIMFGKKKHVDVQFYTEVGEITTDLG--------KHQHMHDRDDLAAEQAERELRHKLKTAFKSFCEKVETMTKSVVEFDTPFRELGFPGAPFRSTVTLQPTSGSLVNLTEWPPFVITLDDVELVHFERVQFHLRNFDMIFVFKEYNKKVAMVNAIPMNMLDHVKEWLNSCDIRYSEGVQSLNWQKIMKTITDDPEGFFEQGGWTFLDPES-GSEGENETAESE-EDEAYNPTDAESDEES-DEDSEYSEASEDSEESDEDLGSDEESGKDWSDLEREAAEEDRNHDYAADDKPRNGKFDSKKHGKSSKHSPSKSSKDKYNSRDKHHSSSSSGNKSSSKDKDRKRSRDDSRDNGHKSKKSRH", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P32558-1", "uniprot_id": "SPT16_YEAST", "id": "P32558-1", "name": "FACT complex subunit SPT16", "aln": "MEELNIDFDVFKKRIELLYSKYNEFE-------GSPNSLLFVLGSSNAENPYQKTTILHNWLLSYEFPATLIALVPGKVIIITSSAKAKHLQKAIDLFKDPESKITLELWQRNNKEPELNKKLFDDVIALIN--SAGKTVGIPEKDSYQGKFMTEWNPVWEAAVKENEFNVIDISLGLSKVWEVKDVNEQAFLSVSS-KGSDKFMDLLSNEMVRAVDEELKITNAKLSDKIENKIDDVKFLKQLSPDLSALCPPNYKFNFDLLDWTYSPIIQSGKKFDLRVSARSTNDQLYGNGCILASCGIRYNNYCSNITRTFLIDPSEEMANNYDFLLTLQKEIVTNILKPGRTPKEVYESVIEYIEKTKPELVPNFTKNIGSLIGLEFRDSNFILNVKNDYRKIQRGDCFNISFGFNNLKDSQSAN----NYALQLADTVQIPLDETEPPRFLTNYTKAKSQISFYFNNEEEDNNKKKS-----SPATKVPSKPDRNSKILRTKLRGEARGGAEDAQKEQIRKENQKKLHEKLEKNGLLRFSAADANGPDSEPRQYFKKYESYVRDSQLPTNIRDLRIHVDWKSQTIILPIYGRPVPFHINSYKNGSKNEEGEYTYLRLNFNSPGSSGG------ISKKVEELPYEESADNQFVRSITLRSKDGDRMSETFKQIADLKKEATKREQERKALADVVQQDKLIENKTGRTKRLDQIFVRPNPDTKRVPSTVFIHENGIRFQSPLRTDSRIDILFSNIKNLIFQSCKGELIVVIHIHLKNPILMGKKKIQDVQFYREASDMSVDETGGGRRGQSRFRRYGDEDELEQEQEERRKRAALDKEFKYFADAIAEASNGLLTVENTFRDLGFQGVPNRSAVFCMPTTDCLVQLIEPPFLVINLEEVEICILERVQFGLKNFDMVFVYKDFNKPVTHINTVPIESLDFLKQWLTDMDIPYTVSTINLNWATIMKSLQDDPYQFFLDGGWNFLATGS-DDEASDESEEEVSEYEASEDDVSDESAFSEDEEGSEVDDDISGDESEDYTGDESEEGEDWDELEKKAARADRGANFRD------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . :* :.: :*:: **:::. . :.:: :* : : * *: *: **:.**:. *: .: . : :::*. * :.*:: : : : ... : :: *:.:* :: . ** :*: ** : *:* *. .:. . *: :*** :: *: .* : :: : * . :.:.:: :* : *: : **:: * * : *: .* :. * ****** :.*:.*. : :: :: * * .: * *::.****: **::::*:: : :** **: :*:*::. * * . :**: .:: ::* **.:: ::.*.:* :*:***:..:::. * : :::. *.: .*:.:*.: :. . .*** :.*** : .* *. .:* .* .::.::::::.:::: ... . . .: .: .* :* : * :: *: *: :*::* :*::.. *:: . .: *: .*:. .: * ::::::::* * :*:*:*::* .**** : ** * . **:*****:** **:: * .: : * : . :: . .:.::*: * :::*. ..** *.: .:*:**.*: . . . :*.::::*** **: .:: * **:*: * ..::***:.*** :**.*.**:*:::*:*** .:::***: ***** *..:::.* :.:: *.*:* ** **. * *.. ** * : : :: : .: .**:*** *.* **: **:..**: * * :*:.*::**: :***** *:****::*:*::.* *: :*::*: ** :*:**.. *: *: .. .*** .***:: *** ** :***.** . . ..:..: *. * *: : : . . *.: . . ..: *.: *.:.*.*:**.:**.:* . ** : ", "identical_positions": 264, "similar_positions": 399, "identity": "23.3%" }, { "cls_id": "homologset.agr.MGI:1891012", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q80YC5-1", "uniprot_id": "FA12_MOUSE", "id": "Q80YC5-1", "name": "Coagulation factor XII", "aln": "MTALLFLGSLLMSLDLTLSAPPWKDSKKFKDAPDGPTVVLTVDGRLCHFPFQYHRQLHHKCIHKRRPGSRPWCATTPNFDEDQQWGYCLEPKKVKDHCSKHNPCHKGGTCINTPNGPHCLCPEHLTGKHCQKEKCFEPQLLKFFHENELWFRTGPGGVARCECKGSEAHCKPVASQACSINPCLNGGSCLLVEDHPLCRCPTGYTGYFCDLDLWATCYEGRGLSYRGQAGTTQSGAPCQRWTVEATYRNMTEKQALSWGLGHHAFCRNPDNDTRPWCFVWSGDRLSWDYCGLEQCQTPTFAPLVVPES----------QEESPSQAPSLSHAPNDSTD--------HQTSLSKTNTMGCGQRFRKGLSSFMRVVGGLVALPGSHPYIAALYWGNNFCAGSLIAPCWVLTAAHCLQNRPAPEELTVVLGQDRHNQSCEWCQTLAVRSYRLHEGFSSITYQHDLALLRLQESKTNSCAILSPHVQPVCLPSGAAPPSETVLCEVAGWGHQFEGAEEYSTFLQEAQVPFIALDRCSNSNVHGDAILPGMLCAGFLEGGTDACQGDSGGPLVCEEGTAEHQLTLRGVISWGSGCGDRNKPGVYTDVANYLAWIQKHIAS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D3ZTE0-1", "uniprot_id": "FA12_RAT", "id": "D3ZTE0-1", "name": "Coagulation factor XII", "aln": "MTALLFLGSLLMSLDLTLSAPPWK-SKEFKDGAGDPSVVLTVDGKLCHFPFQYHRRLYHKCIHKGQPGSRPWCATTPNFDEDQQWGYCLEPKKVKDHCSKHSPCHKGGTCVNTPNGPHCLCPEHLTGKHCQREKCFESQLLKFFHENEIWFRTGPGGVARCQCKGPQAVCKLLTSQVCRVNPCLNGGTCLLVEDHRLCHCPAGYAGPFCDLDLKATCYEDRGLSYRGQAKTTLSGAPCQRWASEATYRNMTETQALSWGLGHHAFCRNPDNDTRPWCYVWSGDRLSWDYCDLEQCQMPTLTSPVSPES----------HDMLKPRPPILQSSPRDSTR--------NQNVVSRTSTVVCGQRFRKRLSSLRRVVGGLVALPGSHPYIAALYWGDSFCAGSLIDPCWVLTAAHCLQKRPAPEELTVVLGQDRHNQSCERCQTLAVHSYRLHEGFSSKTYQHDLALLRLR-GRKNSCAILSPHVQPVCLPSSAAPPSETVLCEVAGWGHQFEGAEEYATFLQEAQVPFISLDRCSSSNVHGDAILPGMLCAGFLEGGADACQGDSGGPLVCDEGVTERQLTLRGVISWGSGCGDRNKPGVYTDVANYLDWIQEHTAF", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P00748-1", "uniprot_id": "FA12_HUMAN", "id": "P00748-1", "name": "Coagulation factor XII", "aln": "MRALLLLGFLLVSLESTLSIPPWEAPKEHKYKAEEHTVVLTVTGEPCHFPFQYHRQLYHKCTHKGRPGPQPWCATTPNFDQDQRWGYCLEPKKVKDHCSKHSPCQKGGTCVNMPSGPHCLCPQHLTGNHCQKEKCFEPQLLRFFHKNEIWYRTEQAAVARCQCKGPDAHCQRLASQACRTNPCLHGGRCLEVEGHRLCHCPVGYTGAFCDVDTKASCYDGRGLSYRGLARTTLSGAPCQPWASEATYRNVTAEQARNWGLGGHAFCRNPDNDIRPWCFVLNRDRLSWEYCDLAQCQTPTQAAPPTPVSPRLHVPLMPAQPAPPKPQPTTRTPPQSQTPGALPAKREQPPSLTRNGPLSCGQRLRKSLSSMTRVVGGLVALRGAHPYIAALYWGHSFCAGSLIAPCWVLTAAHCLQDRPAPEDLTVVLGQERRNHSCEPCQTLAVRSYRLHEAFSPVSYQHDLALLRLQEDADGSCALLSPYVQPVCLPSGAARPSETTLCQVAGWGHQFEGAEEYASFLQEAQVPFLSLERCSAPDVHGSSILPGMLCAGFLEGGTDACQGDSGGPLVCEDQAAERRLTLQGIISWGSGCGDRNKPGVYTDVAYYLAWIREHTVS", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* ***:** **:**: *** ***: .*:.* . :***** *. *********:*:*** ** :**.:**********:**:*****************.**:*****:* *.*******:****:***:*****.***:***:**:*:** ..****:***.:* *: ::**.* ****:** ** **.* **:**.**:* ***:* *:**:.******* * ** ****** *: ******:* ** .**** ********** ****:* . *****:**.* *** ** :. * * : * .*...* : :::...: ****:** ***: ********* *:**********..******* ************.*****:*******:*:*:*** ******:******.**. :**********: . .***:***:********.** ****.**:**************::*********::*:*** .:***.:**************:*************:: .:*::***:*:******************** ** **::* . ", "identical_positions": 407, "similar_positions": 112, "identity": "66.18%" }, { "cls_id": "homologset.agr.MGI:1891017", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "M0RCA3-1", "uniprot_id": "M0RCA3_RAT", "id": "M0RCA3-1", "name": "Zinc finger protein-like 1", "aln": "MGLCKCPKRKVTNLFCFEHRVNVCEHCLVANHAKCIVQSYLQWLQDSDYNPNCRLCNTPLASRETTRLVCYDLFHWACINERAAQLPRNTAPAGYQCPSCNGPIFPPANLAGPVASALREKLATVNWARAGLGLPLIDEVISPEPEPLNSSDFSDWSSFNATTTPVQEERESTAAAPVFYSQVPRPPPSPSRPEQHTVIHMGSTEA-------LTHAPRKVYDTRDDDRTAGVHGDCDDDKYRRRPALGWLAQLLRSRAGSRKRPLTLLQRAGLLLLLGLLGFLALLALMSRLGRAAADSDPNLDPLMNPHIRVGPS-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9DB43-1", "uniprot_id": "ZFPL1_MOUSE", "id": "Q9DB43-1", "name": "Zinc finger protein-like 1", "aln": "MGLCKCPKRKVTNLFCFEHRVNVCEHCLVANHAKCIVQSYLQWLQDSDYNPNCRLCNTPLASRETTRLVCYDLFHWACINERAAQLPRNTAPAGYQCPSCNGPIFPPANLAGPVASALREKLATVNWARAGLGLPLIDEVISPEPEPLNSSDFSDWSSFNATTTSVQEERASTPSAPAFYSQAPRPPPSPSRPEQHTVIHMGSTEA-------LAHAPRKVYDTRDDDRTAGIHGDCDDDKYRRRPALGWLAQLLRSRAGSRKRPLTLLQRAGLLLLLGLLGFLALLALMSRLGRAAADSDPNLDPLMNPHIRVGPS-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O95159-1", "uniprot_id": "ZFPL1_HUMAN", "id": "O95159-1", "name": "Zinc finger protein-like 1", "aln": "MGLCKCPKRKVTNLFCFEHRVNVCEHCLVANHAKCIVQSYLQWLQDSDYNPNCRLCNIPLASRETTRLVCYDLFHWACLNERAAQLPRNTAPAGYQCPSCNGPIFPPTNLAGPVASALREKLATVNWARAGLGLPLIDEVVSPEPEPLNTSDFSDWSSFNASSTPGPEEVDSASAAPAFYSQAPRPPASPGRPEQHTVIHMGNPEP-------LTHAPRKVYDTRDDDRTPGLHGDCDDDKYRRRPALGWLARLLRSRAGSRKRPLTLLQRAGLLLLLGLLGFLALLALMSRLGRAAADSDPNLDPLMNPHIRVGPS-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P62447-1", "uniprot_id": "ZFPL1_DANRE", "id": "P62447-1", "name": "Zinc finger protein-like 1", "aln": "MGLCKCPKKKVTNLFCFKHRVNVCEHCLVSNHNKCIVQSYLQWLQDSDYNPNCSLCIQPLDSQDTVRLVCYDLFHWSCLNELASHQPLNTAPDGYQCPTCQGPVFPPRNLASPVADMLREQLSSVNWARAGLGLPLIEDPEEEETTTHSGTSFSEWSTFETTSVDVSMSNPTLTSLPPHQDGEHIYNNREQSAPNNTVFNMVTTSATDTVTISTVTSPRKLYDTRDLGHSAVMQIDFDDDKYRRRPALNWFAQVLKNCTSTKKKTLALKHRIFLLLLFGVIGFFTLIIIMAKFGRASAETDPNLDPLLNPNIRIGNM-", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VD26-1", "uniprot_id": "ZFPL1_DROME", "id": "Q9VD26-1", "name": "Zinc finger protein-like 1 homolog", "aln": "MGLCKCPKRLVTNQFCFEHRVNVCEHCMVQSHPKCIVQSYLQWLRDSDYISNCTLCGTTLEQGDCVRLVCYHVFHWDCLNARQAALPANTAPRGHQCPACSVEIFPNANLVSPVADALKSFLSQVNWGRNGLGLALLSEEQSSSLKAIKPKVASQAAVSNMTKVHHIHSGG---------ERERTKPNGHDAVSPHSVLLMDAFNPPSAG---DYASSRRPLLPR---QSPIGGTDRDDNKYQRRTPAELFSRWTRRFYAPSSRPP--WRRTWFLVTAGILAFVLFVYLMAWLGRGGS--DAVDEGWNNPNPQPNHYE", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "********: *** ***:*********:* .* ***********:**** .** ** .* . : .*****.:*** *:* : * **** *:***:*. :** **..***. *:. *: ***.* ****.*:.: . . . . . *: : : :.. . . ::*: * .. :.*: .* ::. * **:**:**.. ::: : .. .:. :* :*: *::.*. :: :*: :**..: *. : **: : . ", "identical_positions": 105, "similar_positions": 87, "identity": "33.02%" }, { "cls_id": "homologset.agr.MGI:1891037", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q498R1-1", "uniprot_id": "MTRR_RAT", "id": "Q498R1-1", "name": "Methionine synthase reductase", "aln": "-----MRRFLLLYATQRGQAKAIAEEISEQALSHGFSADLHCVSESEKYDLKTETGPLVMVVSTTGTGDPPDTARKFVKEIHNKTLPTDFFAHLWYGLLGLGDSEYTYFCNGGKVIDKRLQELGAQHFYDTGHADDCVGLELVVEPWIDGLWPALTKHFKSLGGQEDMSDSDTLAQASDAP-LSMAMKPELLHIQSQVELLSLEDVGKRDSELQEQNETNKNQP-SRIEDFDSSLVNSVPPLSQSSLSIPAVSPEYLEVYLQESLGQDENQASVPPSVDPIFQVPISKAVELTTNDAIKTTLLLELDIS-KVEFSHQPGDSFNVICPNSGSEVEDLLQRLQLADKQAHRVILKIKMDTKKKGASLPQHVPEGSSLQFIFTWCLEIRAVPKKAFLRALSDYTSDATEKRRLQELCSKQGAADYNRFIRDASVCLLDLLLTFPSCQPPLNLLLEHLPKLQPRPYSCASSSLLHPD-KLHFVFNIVELPSNTTAASLRKGVCTGWLATLVAPFLQPN-TEVLTADHSDALAPEILISPRATNSFHLPD-DLSAPIIMVGPGTGVAPFVGFLQHREKLQEQHPDGNFGAMWLFFGCRHKDRDYLFREELRHFLKTGVLTHLKVSFSRDAAPEEEEEAPAKYVQDNLQHHSQQVARTLLQENGYIYVCGDAKNMAKDVHDALVEIISKEAGVDKLEAMKTLATLKQEKRYLQDIWS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8C1A3-1", "uniprot_id": "MTRR_MOUSE", "id": "Q8C1A3-1", "name": "Methionine synthase reductase", "aln": "-----MRRFLLLYATQRGQAKAIAEEISEQAVSHGFSADLHCISESEKYDLKTETGPLVMVVSTTGTGDPPDTARKFVKEIHNKTLPTDYFAHLRYGLLGLGDSEYTYFCNGGKVIDKRLQELGAQRFYDTGHADDCVGLELVVEPWIDGLWAALTKHFKSLGGQENMS--DTLSRASDAP-LSTAMKPELLHIQSQVELLRLEDVGERDSELREQNETNRGQQ-GRIEDFDSSLVHSVPPLSQSSLSIPAVPPEYLEVHLQESLGQEENQASVP-SGDPSFQVPISKAIRLTTNDAVKSTLLLELDIS-KIEFSHQPGDSFNVTCPNSDREVEELLQRLQLADKRAHRVILKIKTDTKKKGAALPAHVPEGRSLQFILTWCLEIRAVPKKAFLRALAEHTSSATEKRRLQELCSKQGAADYNRFIRDASVCLLDLLLTFPSCQPPLSLLLEHLPKLQPRPYSCASSSLRHPD-KLHFVFNIVEFPPSTTAASPRKGVCTGWLATLVAPFLQPN-TDVSNADSGDTLAPEIRISPRATNAFHLPE-DPSAPIIMVGPGTGVAPFVGFLQHREKLQEQHPDGKFGAMWLFFGCRHKDRDYLFREELRHFLKTGVLTHLKVSFSRDAAPDGEE-APAKYVQDNLQRHSQQVARTLLQENGYIYVCGDAKNMAKDVNDTLIGIISNEAGVDKLEAMKTLATLKQEKRYLQDIWS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9UBK8-2", "uniprot_id": "MTRR_HUMAN", "id": "Q9UBK8-2", "name": "Methionine synthase reductase", "aln": "-----MRRFLLLYATQQGQAKAIAEEICEQAVVHGFSADLHCISESDKYDLKTETAPLVVVVSTTGTGDPPDTARKFVKEIQNQTLPVDFFAHLRYGLLGLGDSEYTYFCNGGKIIDKRLQELGARHFYDTGHADDCVGLELVVEPWIAGLWPALRKHFRSSRGQEEIS--GALPVASPASSRTDLVKSELLHIESQVELLRFDDSGRKDSEVLKQNAVNSNQSNVVIEDFESSLTRSVPPLSQASLNIPGLPPEYLQVHLQESLGQEESQVSVT-SADPVFQVPISKAVQLTTNDAIKTTLLVELDIS-NTDFSYQPGDAFSVICPNSDSEVQSLLQRLQLEDKREHCVLLKIKADTKKKGATLPQHIPAGCSLQFIFTWCLEIRAIPKKAFLRALVDYTSDSAEKRRLQELCSKQGAADYSRFVRDACACLLDLLLAFPSCQPPLSLLLEHLPKLQPRPYSCASSSLFHPG-KLHFVFNIVEFLSTATTEVLRKGVCTGWLALLVASVLQPN-IHASHEDSGKALAPKISISPRTTNSFHLPD-DPSIPIIMVGPGTGIAPFIGFLQHREKLQEQHPDGNFGAMWLFFGCRHKDRDYLFRKELRHFLKHGILTHLKVSFSRDAPVGEEE-APAKYVQDNIQLHGQQVARILLQENGHIYVCGDAKNMAKDVHDALVQIISKEVGVEKLEAMKTLATLKEEKRYLQDIWS", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F1RE28-1", "uniprot_id": "F1RE28_DANRE", "id": "F1RE28-1", "name": "Methionine synthase reductase", "aln": "MPCEAAAHFLILYGSQRGQAQSIAEEICQQAAEHGFTADISCLSKHDKYNLDSESRPVVFVVSTTGDGDPPDTALKFVRKIKNKSLPHDHLSHLRYALLGLGDTNYANFCNGGKTIDSYLQKLGAKHFYATGHADDGTGLEVVVDPWIEGLWDALKKAFSTMSTSDQQT----LSDCTQDS-NHQNASDQKKNLEVDLQLLKLSEVDSPKGKTVTSDSIATEIG---STSSVASLKESVPPLSESVLNVPALPPSYLEILL---VGTENVEETVLPDKDGYFEVPISKAVQLTQDDAVKTAILLELDISQQQEQVYQPGDAFDILCPNRDSEVEELLLKLDLQMQKNCTVQVNLLKNTSKKAAKVPLHIPQNGSLQFILTWCLEIRSTPKKAFLRALVDFTQNASEKRRLLELCSKQGSADYNSFVRDSSVCVLDLLRAFPSCCPPLSLLFEHLPKLQPRAYSAASSSLQHPG-KVHLVFNVVEFPARPEHP-ARKGLCTGWLVDHVSSILEPHGTALASERPGTSALPKVHVRARPSSTFHLPS-DPCVPVVMVGPGTGVAPFIGFLQQREKEREANQEATFGEMWLFFGCRHKDKDFLFREELEKFVHNGTLSHLIVCFSRDEPDAAETVNRPTYVQHNLILHAKNLAKILLEDKGCLYVCGDAKNMAKDVNDTLLEIIGNELQLDKLDAMKIVAGLREDKRYLQDIWS", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VEV2-1", "uniprot_id": "Q9VEV2_DROME", "id": "Q9VEV2-1", "name": "Methionine synthase reductase", "aln": "--------------------------------------------------------------------------------------------------MDLGAYKLSEYIPAKPLVGNLELCFTDEEQRPTETCGQLKCCDILKFPFAR----------------------------------------------------------------------------------------------------PDFQPSSVEIKE--------------------------SKVLVSADKATETKRVVELTLE--STFDYQPGDTIGILPANKLEQVESLLHRLELLDQADTTCHLKLVFNCANKNAKLPAHIPATTTPREILTHCLSLNFVPQKQLLSALAGFTSDDKERCFLSCLSSKQATEYYQSLILEQGLLFIDILEVCVNCRPPLAFLAEHLPRLLPRPYSIANSPLEASNRELRVIYSLLSLKPG----------------------VTTSMLEAAAQQSSPEHSKKVVIYPRMSNLFRYTERDVGRNQILIAVGTGLAPFLGFLAHKEELIKQQPQQPSGQSWLYIGAKTP-EAVLKREKLMEWQESSLLERLRMCYSRGES--------PSYVQHMLEEDCEDLVEFLMKSETVLYICADGAKISQSIAGVLSRCLQKAMHLTEEEASQLLKKLRKQDKYREDVWL", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :.** : : : . :.. : .. * ..: ::: *: * . *. ::: . : :: :.* :: ::** :. :****::.: .* :*:.** :*:* : ::: : :* * :* *:* : : *:* **.:. *:* :* ** .*.. *: * *.***.: *. :: : .:*:* . .* *** :* ****:* **.** *.*.* .. :::.::.::.: . : . . :: : .* :. *: .. * :::. ***:***:*** ::*: : : : * **::*.: . * *::* .: . . * :* :.:**. . ..***. : . :::.. *::.: :*:*.*. ::::.: ..* : : : : :* : : *:::.:* :*:* ", "identical_positions": 97, "similar_positions": 179, "identity": "13.64%" }, { "cls_id": "homologset.agr.MGI:1891061", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0ABK0LL73-1", "uniprot_id": "A0ABK0LL73_RAT", "id": "A0ABK0LL73-1", "name": "Succinyl-CoA:3-ketoacid-coenzyme A transferase", "aln": "MTQRRGNVRCSHKGHLAFPSLSRSWEPRGSRTMAALRLLAWAFSRRVSAHRPQPTLPHHLIRHYPTT-RCGKVKFYTDPVKAVEGIKDGASVMLGGFGLCGIPENLIGALKTKGVKDLKIISSNVGVDDFGLGILLASKQVRRVVCSYLGENKLCEQLYLAGKLELEMTPQGTLAERIRAGGTGVPAFYTPTGYGTQVQEGGVPIRYSPEGHLITLSQPREVREFEGQHHLLERAIRADFALIKGWKADRSGNVIFRGSARNFNVPMCKAADISVVEVEEIVDVGTFAPEDIHIPNIYVKRVIKGPRFEKRIERLTTRD----SPPAPGSKDQDPKRTRIIKRAALEFKDGMYANLGIGIPVLASNYISPKMTVYLHSENGILGLGPFPLKKEVDPDIINAGKQTVTVIPGGCFFASDDSFAMIRGGHIQLTMLGAMQVSKYGDLANWMVPGKKVKGMGGAMDLVSSKKTKVVVTMEHCTKTKQPKILEKCTMPLTGKSCVDLIITEKAVFEVDRSKGLKLVELWEGSSLDEVKATTGCSFKVCPNLKPMQQIKSDA", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9JJN4-1", "uniprot_id": "SCO2A_MOUSE", "id": "Q9JJN4-1", "name": "Succinyl-CoA:3-ketoacid coenzyme A transferase 2A, mitochondrial", "aln": "--------------------------------MAALRLLAWALPRGVSALRPPPALPHRLIRRYVSD-RSGSVHFYTDPVKAVEGVKDGSTVMLGGFGLCGIPENLIGALKTKGVKDLKIVSSNVGVDDFGLGILLASKQVRRVVCSYLGENALCEKLYLAGELELEMTPQGTLAERIRAGGTGVPAFYTPTGYGTLVQEGGSPIRYAPDGHLITLSEPREVREFQGRFYLLEHAIRADFALIKGWKADRSGNVIFRGSARNFNVPMCKAADISVVEVEEIVDVGTFAPEDIHVPNIYVDRVIKGPKFEKRIERLTTRD----SKPAPGSKDNDPSRTRIIKRAALEFQDGMYANLGIGIPVLASNYISPKMTVYLHSENGILGLGPFPLKNEVDADVINAGKQTVTVVPGGCFFASDDSFAMIRGGHLQLTMLGAMQVSQYGDLANWMVPGKKVKGMGGAMDLVSSKKTRVVVTMEHCTKTKQPKILKKCTMPLTGKRCVDLIITEKAVFEVNHSKGLTLVELWEGSSVDDIKATTACSFAVSPNLKPMQQIKLDA", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9BYC2-1", "uniprot_id": "SCOT2_HUMAN", "id": "Q9BYC2-1", "name": "Succinyl-CoA:3-ketoacid coenzyme A transferase 2, mitochondrial", "aln": "--------------------------------MAALRLLASVLGRGVPAGGSGLALSQGCARCFATS-PRLRAKFYADPVEMVKDISDGATVMIGGFGLCGIPENLIAALLRTRVKDLQVVSSNVGVEDFGLGLLLAARQVRRIVCSYVGENTLCESQYLAGELELELTPQGTLAERIRAGGAGVPAFYTPTGYGTLVQEGGAPIRYTPDGHLALMSQPREVREFNGDHFLLERAIRADFALVKGWKADRAGNVVFRRSARNFNVPMCKAADVTAVEVEEIVEVGAFPPEDIHVPNIYVDRVIKGQKYEKRIERLTILK----EEDGDAGKEED-ARTRIIRRAALEFEDGMYANLGIGIPLLASNFISPSMTVHLHSENGILGLGPFPTEDEVDADLINAGKQTVTVLPGGCFFASDDSFAMIRGGHIQLTMLGAMQVSKYGDLANWMIPGKKVKGMGGAMDLVSSQKTRVVVTMQHCTKDNTPKIMEKCTMPLTGKRCVDRIITEKAVFDVHRKKELTLRELWEGLTVDDIKKSTGCAFAVSPNLRPMQQVAP--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9W058-1", "uniprot_id": "SCOT_DROME", "id": "Q9W058-1", "name": "Succinyl-CoA:3-ketoacid-coenzyme A transferase, mitochondrial", "aln": "-------------------------------------MLCRLVGN--RSLGARYTASIKAIACYSTSGKQRNGKIYESAIDAVADVQDGAQILFGGFGICGIPEKMINALKQKGVKNITGVSNNGGVDDTGLGVLIKQKQVSKVIGSYVGENTELVRQYLEGELAVELTPQGTLAEKIRAGGAGIPAFYTPTGYATLVQEGGAPIKYSKDGKVEISSEKKPVKEFNGKNYVMEESIFADFAFVKAQKADPLGNLVFNKAARNFNAPMCRAAKITVAEVEEIVPIGALSPDEIHVPGIYINRIFKGTNYNKRVERLRITEPKDPSKPAPPPNPAQVLRERIARRVALEFHDGMYANLGIGIPVLSSNYIPKGMNVMLQSENGILGLGPFPTKDKVDPDLINAGKESVTVVPGASYFGSDDSFAMIRGGHVDITILGAMEVSATGDLANWMIPGKLVKGMGGAMDLVAAPGTKVIITMEHNARDGSPKILDTCSLPLTGKGVIDMIISEKAVFTVEKGVGLTLIEVAEGYTVDDIIASTGAKFTVSPNLKKMGQIPV--", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :*. . . : . : . : : ::* ..:. * .:.**: :::****:*****::* ** . **:: :*.* **:* ***:*: :** ::: **:*** ** *:* :*:********:*****:*:*********.* ***** **:*: :*:: *: : *:**:* .::*.:* ****::*. *** **::*. :*****.***:**.::..****** :*::.*::**:*.**:.*::** .::**:*** . . . : : * ** :*.****.************:*:**:*. *.* *:************ :.:**.*:*****::***:**..:*.************:::*:****:** *******:*** ***********:: *:*::**:* :: ***:..*::***** :* **:***** *.: *.* *: ** ::*:: :*.. * *.***: * *: ", "identical_positions": 252, "similar_positions": 151, "identity": "45.24%" }, { "cls_id": "homologset.agr.MGI:1891066", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9JJJ3-1", "uniprot_id": "AQP9_MOUSE", "id": "Q9JJJ3-1", "name": "Aquaporin-9", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MPSEKDRAKKNLVQRLALKS-------------------------------------------------CLAKETLSEFLGTFIMIVLGCGSIAQA------------------------------------VLSREKAGGIITINIGFATAVVMALYATFG--VSGGHINPAVSFAMCTFGRMEWFKFPFYVGAQLLGAFVGAATVFGIYYDGLMAFADGKLLITGENGTAFIFATYPKPFVSVPGAFVDQVVSTMFLLLIVFAIFDSRNLGVPRGLEPIVIGLLIIVISCSLGLNSGCAMNPARDLSPRLFTALAGWGFEVFTFG-NNFWWIPVVGPMIGAVLGGLIYVLFIQMHHSNPD------------------------------------------------------PEVKAEPAENNLEKHELSVIM-------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P56627-1", "uniprot_id": "AQP9_RAT", "id": "P56627-1", "name": "Aquaporin-9", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MPSEKDGAKKSLMQRLALKS-------------------------------------------------RIAKETLSEFLGTFIMIVLGCSSIAQA------------------------------------VLSRERFGGIITINIGFASAVVMALYVTFG--ISGGHINPAVSFAMCAFGRMEWFKFPFYVGAQFLGAFVGAATVFGIYYDGLMAFAGGKLLVVGENATAFIFATYPAPFISTPGAFVDQVVSTMFLLLIVFAMFDSRNLGVPRGLEPVVIGLLIIVLSCSLGLNSGCAMNPARDLSPRLFTALAGWGFEVFTVG-NNFWWIPVVGPMIGAFLGGLIYILFIQMHHSKLD------------------------------------------------------PDMKAEPSENNLEKHELSVIM-------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O43315-1", "uniprot_id": "AQP9_HUMAN", "id": "O43315-1", "name": "Aquaporin-9", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MQPEGAEKGKSFKQRLVLKS-------------------------------------------------SLAKETLSEFLGTFILIVLGCGCVAQA------------------------------------ILSRGRFGGVITINVGFSMAVAMAIYVAGG--VSGGHINPAVSLAMCLFGRMKWFKLPFYVGAQFLGAFVGAATVFGIYYDGLMSFAGGKLLIVGENATAHIFATYPAPYLSLANAFADQVVATMILLIIVFAIFDSRNLGAPRGLEPIAIGLLIIVIASSLGLNSGCAMNPARDLSPRLFTALAGWGFEVFRAG-NNFWWIPVVGPLVGAVIGGLIYVLVIEIHHPEPD------------------------------------------------------SVFKTEQSEDKPEKYELSVIM-------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P23900-1", "uniprot_id": "FPS1_YEAST", "id": "P23900-1", "name": "Glycerol uptake/efflux facilitator protein", "aln": "------------------------------------MSNPQKALNDFLSSESVHTHDSSRKQSNKQSSDEGRSSSQPSHHHSGGTNNNNNNNNNNNNSNNNNNGNDGGNDDDYDYEMQDYRPSPQSARPTPTYVPQYSVESGTAFPIQEVIPSAYINTQDINHKDNGPPSASSNRAFRPRGQTTVS---------ANVLNIEDFYKNADDAHTIPESHLSRRRSRSRATSNAGHSANTGATNGRTTGAQTNMESNESPRNVPIMVKPKTLYQNPQTPTVLPSTYHPINKWSSVKN-------------------------------------------------TYLKEFLAEFMGTMVMIIFGSAVVCQVNVAGKIQQDNFNVALDNLNVTGSSAETIDAMKSLTSLVSSVAGGTFDDVALGWAAAVVMGYFCAGGSAISGAHLNPSITLANLVYRGFPLKKVPYYFAGQLIGAFTGALILF-IWYKRVLQEAYSDWWMN--ESVAGMFCVFPKPYLSSGRQFFSEFLCGAMLQAGTFALTDP-YTCLSSDVFPLMMFILIFIINASMAYQTGTAMNLARDLGPRLALYAVGFDHKMLWVHHHHFFWVPMVGPFIGALMGGLVYDVCIYQGHESPVNWSLPVYKEMIMRAWFRRPGWKKRNRARRTSDLSDFSYNNDDDEEFGERMALQKTKTKSSISDNENEAGEKKVQFKSVQRGKRTFGGIPTILEEEDSIETASLGATTTDSIGLSDTSSEDSHYGNAKKVT", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P43549-1", "uniprot_id": "AQY3_YEAST", "id": "P43549-1", "name": "Aquaglycerol porin AQY3", "aln": "MSYESGRSSSSSESTRPPTLKEEPNGKIAWEESVKKSRENNENDSTLLRRKLGETRKAIETGGSSRNKLSALTPLKKVVDERKDSVQPQVPSMGFTYSLPNLKTLNSFSDAEQARIMQDYLSRGVNQGNSNNYVDPLYRQLNPTMGSSRNRPVWSLNQPLPHVLDRGLAAKMIQKNMDARSRASSRRGSTDISRGGSTTSVKDWKRLLRGAAPGKKLGDIEAQTQRDNTVGADVKPTKLEPENPQKPSNTHIENVSRKKKRTSHNVNFSLGDESYASSIADAESRKLKNMQTLDGSTPVYTKLPEELIEEENKSTSALDGNEIGASEDEDADIMTFPNFWAKIRYHMREPFAEFLGTLVLVIFGVGGNLQA------------------------------------TVTKGSGGSYESLSFAWGFGCMLGVYVAGG--ISGGHINPAVTISMAIFRKFPWKKVPVYIVAQIIGAYFGGAMAYGYFWSSITEFEGGPHIRT--TATGACLFTDPKSYVTWRNAFFDEFIGASILVGCLMALLDDSNAPPGNGMTALIIGFLVAAIGMALGYQTSFTINPARDLGPRIFASMIGYGPHAFHLTHWWWTWGAWGGPIAGGIAGALIYDIFIFTGCESPVNYPDNGYIENRVG-----------------------------------------KLLHAEFHQNDGTVSDESGVNSNSNTGSKKSVPTSS----------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . : : : :.. :* ::**:**::::::* . *. :: * : ..:. . :. : : * :**.*:**::::: : : *.* *. .*::**: *. : ::. : . ... : . * .::: * .:.: :* :*: * .: .: : :*: : ::. ::. ::* ****.**: *:. . : : * . **: *.. *.*:* : * . ::. ::. : . ", "identical_positions": 43, "similar_positions": 109, "identity": "5.61%" }, { "cls_id": "homologset.agr.MGI:1891112", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q3MHS7-1", "uniprot_id": "Q3MHS7_RAT", "id": "Q3MHS7-1", "name": "GDP-mannose 4,6 dehydratase", "aln": "-----------MAHAPASCRRYP-----GSGD------GEMGKLR-KVALITGITGQDGSYLAEFLLEKGYEVHGIVRRSSSFNTGRIEHLYKNPQAHIEGNMKLHYGDLTDSTCLVKIINEVKPTEIYNLGAQSHVKISFDLAEYTADVDGVGTLRLLDAIKTCGLINSVKFYQASTSELYGKVQEIPQKETTPFYPRSPYGAAKLYAYWIVVNFREAYNLFAVNGILFNHESPRRGANFVTRKISRSVAKIYLGQLECFSLGNLDAKRDWGHAKDYVEAMWLMLQNDEPEDFVIATGEVHSVREFVEKSFMHIGKTIVWEGKNENEVGRCKETGKIHVTVDLKYYRPTEVDFLQGDCSKAQQKLNWKPRVAFDELVREMVQADVELMRTNPNA", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8K0C9-1", "uniprot_id": "GMDS_MOUSE", "id": "Q8K0C9-1", "name": "GDP-mannose 4,6 dehydratase", "aln": "-----------MAQAPAKCPSYP-----GSGD------GEMGKLR-KVALITGITGQDGSYLAEFLLEKGYEVHGIVRRSSSFNTGRIEHLYKNPQAHIEGNMKLHYGDLTDSTCLVKIINEVKPTEIYNLGAQSHVKISFDLAEYTADVDGVGTLRLLDAIKTCGLINSVKFYQASTSELYGKVQEIPQKETTPFYPRSPYGAAKLYAYWIVVNFREAYNLFAVNGILFNHESPRRGANFVTRKISRSVAKIYLGQLECFSLGNLDAKRDWGHAKDYVEAMWLMLQNDEPEDFVIATGEVHSVREFVEKSFMHIGKTIVWEGKNENEVGRCKETGKVHVTVDLKYYRPTEVDFLQGDCSKAQQKLNWKPRVAFDELVREMVQADVELMRTNPNA", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O60547-1", "uniprot_id": "GMDS_HUMAN", "id": "O60547-1", "name": "GDP-mannose 4,6 dehydratase", "aln": "-----------MAHAPARCPSAR-----GSGD------GEMGKPR-NVALITGITGQDGSYLAEFLLEKGYEVHGIVRRSSSFNTGRIEHLYKNPQAHIEGNMKLHYGDLTDSTCLVKIINEVKPTEIYNLGAQSHVKISFDLAEYTADVDGVGTLRLLDAVKTCGLINSVKFYQASTSELYGKVQEIPQKETTPFYPRSPYGAAKLYAYWIVVNFREAYNLFAVNGILFNHESPRRGANFVTRKISRSVAKIYLGQLECFSLGNLDAKRDWGHAKDYVEAMWLMLQNDEPEDFVIATGEVHSVREFVEKSFLHIGKTIVWEGKNENEVGRCKETGKVHVTVDLKYYRPTEVDFLQGDCTKAKQKLNWKPRVAFDELVREMVHADVELMRTNPNA", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VMW9-1", "uniprot_id": "GMDS_DROME", "id": "Q9VMW9-1", "name": "GDP-mannose 4,6-dehydratase", "aln": "MLNTRLIAMSTSDGAPETKKQRPESSSNGSKDQNGTEAGAEGDSRDKVALITGITGQDGSYLAEFLLKKDYEVHGIIRRASTFNTTRIEHLYADPKAHKGGRMKLHYGDMTDSSSLVKIINMVKPTEIYNLAAQSHVKVSFDLSEYTAEVDAVGTLRILDAIRTCGMEKNVRFYQASTSELYGKVVETPQNEQTPFYPRSPYACAKMYGFWIVINYREAYNMYACNGILFNHESPRRGENFVTRKITRSVAKIYHKQMEYFELGNLDSKRDWGHASDYVEAMWMMLQRESPSDYVIATGETHSVREFVEAAFKHIDREITWKGKGVDEVGVENGTGIVRVRINPKYFRPTEVDLLQGDASKANRELNWTPKVTFVELVSDMMKADIELMRKNPIA", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ** ** * * *. * :********************:*.******:**:*:*** ****** :*:** *.*******:***:.****** *********.******:****:****:**.*****:***::***: :.*:************* * **:* *********..**:*.:***:*:*****::* ************* *******:******* *:* *.*****:*******.*******:***.:.*.*:******.******** :* **.: *.*:**. :*** : ** ::* :: **:******:****.:**:::***.*:*:* *** :*::**:****.** *", "identical_positions": 257, "similar_positions": 74, "identity": "65.06%" }, { "cls_id": "homologset.agr.MGI:1891123", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9D808-1", "uniprot_id": "KCNE2_MOUSE", "id": "Q9D808-1", "name": "Potassium voltage-gated channel subfamily E member 2", "aln": "MATLANLTQTLEDAFKKIFITYMDSWRRNTTAEEQALQARVDAENFYYVILYLMVMIGMFSFIVVAILVSTVKSKRREHSQHPYHQYIVEDWQEKYKSQILHLEDSKATIHENMGATGFTVSP", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P63161-1", "uniprot_id": "KCNE2_RAT", "id": "P63161-1", "name": "Potassium voltage-gated channel subfamily E member 2", "aln": "MTTLANLTQTLEDAFKKVFITYMDSWRRNTTAEQQALQARVDAENFYYVILYLMVMIGMFAFIVVAILVSTVKSKRREHSQDPYHQYIVEDWQQKYRSQILHLEDSKATIHENLGATGFTVSP", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9Y6J6-1", "uniprot_id": "KCNE2_HUMAN", "id": "Q9Y6J6-1", "name": "Potassium voltage-gated channel subfamily E member 2", "aln": "MSTLSNFTQTLEDVFRRIFITYMDNWRQNTTAEQEALQAKVDAENFYYVILYLMVMIGMFSFIIVAILVSTVKSKRREHSNDPYHQYIVEDWQEKYKSQILNLEESKATIHENIGAAGFKMSP", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*:**:*:******.*:::******.**:*****::****:********************:**:****************:.***********:**:****:**:********:**:**.:**", "identical_positions": 99, "similar_positions": 24, "identity": "80.49%" }, { "cls_id": "homologset.agr.MGI:1891124", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9WTW2-1", "uniprot_id": "KCNE3_MOUSE", "id": "Q9WTW2-1", "name": "Potassium voltage-gated channel subfamily E member 3", "aln": "METSNGTETWYMSLHAVLKALNTTLHSHLLCRPGPGPG----PDNQTEDRRASLPGRNDNSYMYILFVMFLFAVTVGSLILGYTRSRKVDKRSDPYHVYIKNRVSMI", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9JJV7-1", "uniprot_id": "KCNE3_RAT", "id": "Q9JJV7-1", "name": "Potassium voltage-gated channel subfamily E member 3", "aln": "METSNGTETWYKSLHAVLKALNTTLHSHLLCRPGPGPGSGTGPDNQTEDHRASLPGRNDNSYMYILFVMFLFAVTVGSLILGYTRSRKVDKRSDPYHVYIKNRVSMI", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9Y6H6-1", "uniprot_id": "KCNE3_HUMAN", "id": "Q9Y6H6-1", "name": "Potassium voltage-gated channel subfamily E member 3", "aln": "METTNGTETWYESLHAVLKALNATLHSNLLCRPGPGLG----PDNQTEERRASLPGRDDNSYMYILFVMFLFAVTVGSLILGYTRSRKVDKRSDPYHVYIKNRVSMI", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "***:******* **********:****:******** * ******::*******:*************************************************", "identical_positions": 95, "similar_positions": 6, "identity": "88.79%" }, { "cls_id": "homologset.agr.MGI:1891125", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q71FD8-1", "uniprot_id": "Q71FD8_RAT", "id": "Q71FD8-1", "name": "", "aln": "---------------------------------------------------MLRMEPLNSTHPSAAASSSPLESHVSSNSGGNGNEYFYILVVMSFYGIFLIGIMLGYMKSKRREKKSSLLLLYKDEERLWGEAMKPLPMMSGLRSGQVPMMLNMLQESVAPALSCTLCSMEGDSVSSESSSPDVHLTIQEEGADEELEETSETPLNESSEGSTENIHQNS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9WTW3-1", "uniprot_id": "KCNE4_MOUSE", "id": "Q9WTW3-1", "name": "Potassium voltage-gated channel subfamily E member 4", "aln": "---------------------------------------------------MLRMEPLNSTYPSAAASSSPLESHVPSNSSGNGNEYFYILVVMSFYGVFLIGIMLGYMKSKRREKKSSLLLLYKDEERLWGEAMKPLPMMSGLRSGQVPMMLNMLQESVAPALSCTLCSMEGDSVSSESSSPDVHLPIQEEGADDELEETSETPLNDSSEGSSENIHQNS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8WWG9-1", "uniprot_id": "KCNE4_HUMAN", "id": "Q8WWG9-1", "name": "Potassium voltage-gated channel subfamily E member 4", "aln": "MHFLTIYPNCSSGVVRAQSRTEQKNPLGLDDLGIQNLGQTVSLAPAVEAASMLKMEPLNSTHPGTAASSSPLESRAAGGGSGNGNEYFYILVVMSFYGIFLIGIMLGYMKSKRREKKSSLLLLYKDEERLWGEAMKPLPVVSGLRSVQVPLMLNMLQESVAPALSCTLCSMEGDSVSSESSSPDVHLTIQEEGADDELEETSETPLNESSEGSSENIHQNS", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " **:*******:*.:*********:......*****************:****************************************::***** ***:************************************.*******:***********:*****:*******", "identical_positions": 150, "similar_positions": 19, "identity": "67.87%" }, { "cls_id": "homologset.agr.MGI:1891150", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q60969-1", "uniprot_id": "STYX_MOUSE", "id": "Q60969-1", "name": "Serine/threonine/tyrosine-interacting protein", "aln": "MEDVKLEFPSLPQCKDDAEEWTYPMRREMQEVLPGLFLGPYSSAMKSKLPILQKHGITHIICIRQNIEANFIKPNFQQLFRYLVLDIADNPVENIIRFFPMTKEFIDGSLQNGGKVLVHGNAGISRSAAFVIAYIMETFGMKYRDAFAYVQERRFCINPNAGFVHQLQEYEAIYLAKLTIQMMSPLQIERSLAVHSGTTGSVKRTHEEDDDFGNMQVATAQNG", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8I5ZMB8-1", "uniprot_id": "A0A8I5ZMB8_RAT", "id": "A0A8I5ZMB8-1", "name": "Serine/threonine/tyrosine-interacting protein", "aln": "MEDVKLEFPSLPQCKDDAEEWTYPMRREMQEVLPGLFLGPYSSAMKSKLPILQKHGITHIICIRQNIEANFIKPNFQQLFRYLVLDIADNPVENIIRFFPMTKEFIDGSLQNGGKVLVHGNAGISRSAAFVIAYIMETFGMKYRDAFAYVQERRFCINPNAGFVHQLQEYEAIYLAKLTIQMMSPLQIERSLSVHSGTTGSVKRTYEDDDDFGNMQVATAQNG", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8WUJ0-1", "uniprot_id": "STYX_HUMAN", "id": "Q8WUJ0-1", "name": "Serine/threonine/tyrosine-interacting protein", "aln": "MEDVKLEFPSLPQCKEDAEEWTYPMRREMQEILPGLFLGPYSSAMKSKLPVLQKHGITHIICIRQNIEANFIKPNFQQLFRYLVLDIADNPVENIIRFFPMTKEFIDGSLQMGGKVLVHGNAGISRSAAFVIAYIMETFGMKYRDAFAYVQERRFCINPNAGFVHQLQEYEAIYLAKLTIQMMSPLQIERSLSVHSGTTGSLKRTHEEEDDFGTMQVATAQNG", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "***************:***************:******************:************************************************************ ********************************************************************************:********:***:*::****.*********", "identical_positions": 213, "similar_positions": 9, "identity": "95.52%" }, { "cls_id": "homologset.agr.MGI:1891158", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3Z977-1", "uniprot_id": "D3Z977_RAT", "id": "D3Z977-1", "name": "", "aln": "----MAMSELATQKSGEGTVS---------------RLLNVVESELQAGREKG---------------------------DPTEKQLQIILEDAPLWQRFKEVTNEMIVTKNGRRMFPVLKISVTGLDPNAMYSLLLDFVPTDSHRWKYVNGEWVPAGKPEVSSHSCVYIHPDSPNFGAHWMKAPISFSKVKLTNKLSGGGQIMLNSLHKYEPQVHIVRVGGAHRMVMNCSFPETQFIAVTAYQNEEITALKIKYNPFAKAFLDAKER------------------NHLKEIPEAVSESQHVTYSHLGGWILSNP-----DGMCT-TGSANYQYATPLP-------LPAPHTRHGCEHYAGLRGHR-----------QAPYPSAYMHRNHSPSVNLIESSSNNLQVFSGPES-----------WTSLPSAPHGGILSVP---HTSG-----------------------------PINPGP--------------SPYPCLWTISNG---------GGGPVASGSEVHASASGTFLLGSPTVTSPSSLLPTQATTSAG--------------------------------------------------VEVLGEP------------SLTSIAVSTWTAVASHPL---------PGWGGPGGAGRHSPSSLDS------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q99ME7-1", "uniprot_id": "TBX19_MOUSE", "id": "Q99ME7-1", "name": "T-box transcription factor TBX19", "aln": "------MSELATQKAGEGTVS---------------RLLNVVESELQAGREKG---------------------------DPTEKQLQIILEDAPLWQRFKEVTNEMIVTKNGRRMFPVLKISVTGLDPNAMYSLLLDFVRTDSHRWKYVNGEWVPAGKPEVSSHSCVYIHPDSPNFGAHWMKAPISFSKVKLTNKLNGGGQIMLNSLHKYEPQVHIVRVGGAHRMVMNCSFPETQFIAVTAYQNEEITALKIKYNPFAKAFLDAKER------------------NHLKDVPEAISESQHVTYSHLGGWILSNP-----DGVCT-AANSNYQYATPLP-------LPAPHTHHGCEHYAGLRGHR-----------QAPYPSAYMHRNHSPSVNLIESSSNNLQVFSGPDS-----------WTSLSSTPHASILSVP---HSNG-----------------------------PINPGP--------------SPYPCLWTISNG---------GGGPVASGSEVHASTSGTILLGNPAVTSPSSLLPTQATTSAG--------------------------------------------------VEVLGEP------------SLTSIAVSTWTAVASHPL---------PGWGGPGGAGRHSSSSLDS------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O60806-1", "uniprot_id": "TBX19_HUMAN", "id": "O60806-1", "name": "T-box transcription factor TBX19", "aln": "----MAMSELGTRKPSDGTVS---------------HLLNVVESELQAGREKG---------------------------DPTEKQLQIILEDAPLWQRFKEVTNEMIVTKNGRRMFPVLKISVTGLDPNAMYSLLLDFVPTDSHRWKYVNGEWVPAGKPEVSSHSCVYIHPDSPNFGAHWMKAPISFSKVKLTNKLNGGGQIMLNSLHKYEPQVHIVRVGSAHRMVTNCSFPETQFIAVTAYQNEEITALKIKYNPFAKAFLDAKER------------------NHLRDVPEAISESQHVTYSHLGGWIFSNP-----DGVCT-AGNSNYQYAAPLP-------LPAPHTHHGCEHYSGLRGHR-----------QAPYPSAYMHRNHSPSVNLIESSSNNLQVFSGPDS-----------WTSLSSTPHASILSVP---HTNG-----------------------------PINPGP--------------SPYPCLWTISNG---------AGGPSGPGPEVHASTPGAFLLGNPAVTSPPSVLSTQAPTSAG--------------------------------------------------VEVLGEP------------SLTSIAVSTWTAVASHPF---------AGWGGPGAGGHHSPSSLDG------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P55965-1", "uniprot_id": "BYN_DROME", "id": "P55965-1", "name": "T-related protein", "aln": "MTTSHILSAVDPTTGLSGNVSGGGGGGGAGGGAGSGSPQHVTHNGHGHGHGLGGVAAVSGGGASVSGNGGHRVVGGAGSPNELDRNLRISLDDRELWLRFQNLTNEMIVTKNGRRMFPVVKISASGLDPAAMYTVLLEFVQIDSHRWKYVNGEWVPGGKAEVPPSNPIYVHPESPNFGAHWMKEPISFAKVKLTNKTNGNGQIMLNSLHKYEPRVHLVRVGSEQRHVVTYPFPETQFIAVTAYQNEEVTSLKIKYNPFAKAFLDAKERPDTLYPHDTHYGWLIPPPTHYTAAAAAVAAPPPLSIAQSHGLVASCPSVSSAESVGPSSGGSCDRYGRSLSSRSVAPTRTTPYSRPRVVSGSGSNGSAGNASSTSPQPPSAPQTPTSLHSTSTGSVSTSVSSSSGGGIGSAPSTGCFSSSYAQSGFMSVDASPTASVFSYPSSWQSNGNYWNATSVPGPMPMNVCSGRNISSHNSPSPTNGSPSYTTSSPSYTIHHLTPHSHQYNMAQTDIYGTGVGVGGGAGTTGSPQAAYGAAAHQVYHPTPTSPTHQLYTNAVLNAPSALSYSASGWHNGSGAEYGLYQNAAAAYYQPEYIPLEIGYATHPLEPVDVSKTLDDPQAAMYKPSDEQGSVITLECASSSLKSSHDIKIESSSLEHAGERGTVGGGAAVVSVPTAVVNGAPAVAADTWTPLTPPQSTLQ", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :* : . . .*.** :*... *: * : :::*:* *:* ** **:::****************:***.:**** ***::**:** **************.**.**.. . :*:**:********** ****:******* .*.*************:**:****. :* * . .****************:*:****************** .* . *:: . :: :: * : * * :.: . :..: :*. .*. .:*::: :* .* .** ..: :* . : **. ***.. : *.*.: : *: ::* ..::* * ::.* * * .* :*:. :.::: .**. .*. * ..: : *: ***. * *:* .* :.*.:* *: :: :: : :** : .* *. ..* * . ", "identical_positions": 194, "similar_positions": 137, "identity": "27.83%" }, { "cls_id": "homologset.agr.MGI:1891160", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "M0R868-1", "uniprot_id": "M0R868_RAT", "id": "M0R868-1", "name": "Sulfotransferase", "aln": "----------MSRSSPRALPPGALPRPLPAAPAAVQRALLPPWPRRAGRRWPASPLGMKVFRRKALVLCAGYALLLVLTMLNLLDYKWHKEPLQQCNPDGPLGAAVGAAGAGWGRPGSPPAAPPRAHSRMD---------PRTPYRPPAAGVGAVPAAAAGSVGAAASLGNATRGTRGGGDKRQLVYVFTTWRSGSSFFGELFNQNPEVFFLYEPVWHVWQKLYPGDAVSLQGAARDMLSALYRCDLSVFQLYSPAGSGGRNLTTLGIFGAATNKVVCSSPLCPAYRKEVVGLVDDRVCKKCPPQRLARFEEECRKYRTLVIKGVRVFDVAVLAPLLKDPALD-LKVIHLVRDPRAVASSRIRSRHGLIRESLQVVRSRDPRAHRMPFLEAAGHKLGAKKEGMGGPADYHALGAMEVICNSMAKTLQTALQPPDWLQGHYLVVRYEDLVGDPVKTLRRVYDFVGLLVSPEMEQFALNMTSGSGSSSKPFVVSARNATQAANAWRTALTFQQIKQVEEFCYQPMAVLGYERVNSPEEVKDLSKSLLRKPRL----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q80WV3-1", "uniprot_id": "CHST2_MOUSE", "id": "Q80WV3-1", "name": "Carbohydrate sulfotransferase 2", "aln": "----------MSRSSPRALPPGALPRPLPAAPAAVQRALLPPWPRRAGRRWPASPLGMKVFRRKALVLCAGYALLLVLTMLNLLDYKWHKEPLQQCNPDGPLGAAVGAAGAGWGRPGSPPAAPPRAHSRMD---------PRTPYRPPAAGVGAVPAAAAGSAGAAASLGNATRGTRGGGDKRQLVYVFTTWRSGSSFFGELFNQNPEVFFLYEPVWHVWQKLYPGDAVSLQGAARDMLSALYRCDLSVFQLYSPAGSGGRNLTTLGIFGAATNKVVCSSPLCPAYRKEVVGLVDDRVCKKCPPQRLARFEEECRKYRTLVIKGVRVFDVAVLAPLLKDPALD-LKVIHLVRDPRAVASSRIRSRHGLIRESLQVVRSRDPRAHRMPFLEAAGHKLGAKKEGMGGPADYHALGAMEVICNSMAKTLQTALQPPDWLQGHYLVVRYEDLVGDPVKTLRRVYDFVGLLVSPEMEQFALNMTSGSGSSSKPFVVSARNATQAANAWRTALTFQQIKQVEEFCYQPMAVLGYERVNSPEEVKDLSKTLLRKPRL----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9Y4C5-1", "uniprot_id": "CHST2_HUMAN", "id": "Q9Y4C5-1", "name": "Carbohydrate sulfotransferase 2", "aln": "----------MSRSPQRALPPGALPRLLQAAPAAAPRALLPQWPRRPGRRWPASPLGMKVFRRKALVLCAGYALLLVLTMLNLLDYKWHKEPLQQCNPDGPLGAAAGAAGGSWGRPGPPPAGPPRAHARLD---------LRTPYRPPAAAVGAAPAAAAGMAGVAAPPGNGTRGTGGVGDKRQLVYVFTTWRSGSSFFGELFNQNPEVFFLYEPVWHVWQKLYPGDAVSLQGAARDMLSALYRCDLSVFQLYSPAGSGGRNLTTLGIFGAATNKVVCSSPLCPAYRKEVVGLVDDRVCKKCPPQRLARFEEECRKYRTLVIKGVRVFDVAVLAPLLRDPALD-LKVIHLVRDPRAVASSRIRSRHGLIRESLQVVRSRDPRAHRMPFLEAAGHKLGAKKEGVGGPADYHALGAMEVICNSMAKTLQTALQPPDWLQGHYLVVRYEDLVGDPVKTLRRVYDFVGLLVSPEMEQFALNMTSGSGSSSKPFVVSARNATQAANAWRTALTFQQIKQVEEFCYQPMAVLGYERVNSPEEVKDLSKTLLRKPRL----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "K7DYB2-1", "uniprot_id": "K7DYB2_DANRE", "id": "K7DYB2-1", "name": "Sulfotransferase", "aln": "---------------MRSNQFLQLQLPALGEKNGVYDRNLKTYRNHSTKIITQPGIVMKVLRRKRIILFIAYFLLLVLTMLNLANYRWTKEP-QQCN---------------------VQMRSTPYQGRSD---------MRFLYRPSLA------------------------------KKRQLVYVLTTWRSGSSFFGELFNQHPEVFFLYEPMWHIWQKLYPGDAVSLQGAARDMLSSLYRCDLSVFQLYNSPG--GKNFTSLGLFGATLNKVICSYPLCSAYRKDVVGMVDDKVCKKCPPQSLRLLEEECLKYNTIVIKGVRVLDVNVLAPLMEDPSLD-LKVIHLVRDPRAVANSRIKSRHGLIRENLQVVRSRDPKLRRIHFVDPG-HKIS-KKDGA----DYHSVGAMEVICDRTYRSLRTALNPPAWLKGKYLAVRYEDLVDNPVKTLRNVYQFANISANLDIESFALNMTNGTSSSSKPFIVSARNATQAASAWRTVLSIQQIKQVEEYCHHAMAILGYEHVRTAGEAKDLSKSLLTASKL----", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A5PM89-1", "uniprot_id": "A5PM89_DANRE", "id": "A5PM89-1", "name": "Sulfotransferase", "aln": "---------------MK-NKPYPLKFTPPWEKNAGFGRKHKPCARSHTKIIANPGIVMKVLRRKKIIMFLAYFLLVALTMLNLANYKWTKEP-QQCS---------------------QPMQGVNFQSRSD---------IRYLYKAPQV------------------------------KKRQLVYVLTTWRSGSSFFGELFNQNPDVFFLYEPMWHIWQKLYPGDAVSLQGAARDMLSSLYRCDFSVFQLYNSPG--GKNITSLGLFGAAINKVICSYPFCSSYRKDVVGMVDEKICRKCPPQSLQMLEEECLKYNTIVIKGVRILDVNILAPLMEDPSLN-LKVVHLVRDPRAVANSRIKSRHGLIRENLQVVRSRDPKLRRVPFVDPN-HKMN-KKDGS----DYHSIGAMEVICEQMSKTLKTALHPPSWFKGKYMTVRYEDLVENPVRSVRNVYRFVNLSANHDIEIFAMNMTTGPSASTKPFIVSSRNATQAANAWRTVLNYQQIRQVEEYCQHSMSLLGYLRVRTAGEAKDLSRPLLTVPKI----", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VMC4-1", "uniprot_id": "Q9VMC4_DROME", "id": "Q9VMC4-1", "name": "Sulfotransferase domain-containing protein", "aln": "--------------------------------------------------MVSLSRTSKLT--VACVGVYTTYVLFIFFLLPMLMPDPVTLQRSLVS------------------------------------------------------------------YSTSHLGDIRNLTLDAGGQPIRSMLVTFRGSGALTLLDNLAHQPGCYQHYAPLIAYESRSIAAK---EHHRALDELAALYNCDYNKSAEMIQWG---MRSPVFRRFYGAQAKICRSYSQEACWDPETM----AAVCKLYPFINMAVYN----------------LRLNLLASLLERKDLN-LNIMLLVRDPRGTIYSRMNNKWCSDERDCEA----------------------------------------QELCGDMVSDYQMVETLTQAYPQRFSIIRYEDLFLQPDESIKQVFDFYGLPLERNRTRIQKMHPRSGYFFQS--SRWKELSSQSAFEWISEMMVDDIGAVQDVCGQAMDLWGYRSIQDFNHFSP--ESFQPIMDKAY--", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VMC3-1", "uniprot_id": "Q9VMC3_DROME", "id": "Q9VMC3-1", "name": "Sulfotransferase domain-containing protein", "aln": "MSTGIGSSSSSTEEQQHLELSADLEACSLLGPQDPSNVDTGRTRAKQRLSLNGKRRRSRMSRRANLIGICGVSSLCILLLIATTQHRPLTTPFNQSAGRDQGASVDGGPSNSLARSAFYDRFQQQLQQQQQSSQTAVYNLTATIVDVLSAQRSRILAEMENFEYPRGGAERLTDMTPETNGTPVRSVVVTSWRSGSTFLGDILNSIPGNFYHYEPLLDFGIKQIRDPD--DQELAVQNLKNLLNCDYADMIDYLNFG---KTHTYLFEHNTRLWDVCREFP-RFCWRPAFL----TRFCRLFPIQSMKTVR----------------LRLAQAEKLLEDQSLSSVRIVLLVRDPRGTMQSRRHRVWCGGNEDCEDP---------------------------------------RLVCQDLRDDYKTAEVLLLKYPSRFRTVRYEDLSLSPSEMTQDILQFYGLPFDPAVEEFLDTHTKVNIGGVS--STYRDSRS-APFHWMQDLKPEEIKQIQDVCTEAMDLWGYRRIENFNNFSTTQQTFDPMVMPPPFT", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :: : * : :: . . :.* **: : : : * : * *: : : * : * * .** * . : . .: . . .: : .*: * : . : : *:. *. :.:: ******.. ** . ... : . :* : . :: :***** .* . : : * .: . : . . : :. * : ::* ::: * ..* : ** :. . . ..: ", "identical_positions": 39, "similar_positions": 86, "identity": "7.04%" }, { "cls_id": "homologset.agr.MGI:1891189", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P60841-1", "uniprot_id": "ENSA_RAT", "id": "P60841-1", "name": "Alpha-endosulfine", "aln": "MSQKQE--EENPAEETGEEK------QDTQEKEGILPEKAEEAKLKAKYPSLGQKPGG-SDFLMKRLQKGQKYFDSGDYNMAKAKMKNKQLP-SAGADKNLVTGDHIPTPQDLPQRKSS----------------LVT--SKLAGGQVE---------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P60840-1", "uniprot_id": "ENSA_MOUSE", "id": "P60840-1", "name": "Alpha-endosulfine", "aln": "MSQKQE--EENPAEETGEEK------QDTQEKEGILPEKAEEAKLKAKYPSLGQKPGG-SDFLMKRLQKGQKYFDSGDYNMAKAKMKNKQLP-SAGADKNLVTGDHIPTPQDLPQRKSS----------------LVT--SKLAGGQVE---------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O43768-1", "uniprot_id": "ENSA_HUMAN", "id": "O43768-1", "name": "Alpha-endosulfine", "aln": "MSQKQE--EENPAEETGEEK------QDTQEKEGILPERAEEAKLKAKYPSLGQKPGG-SDFLMKRLQKGQKYFDSGDYNMAKAKMKNKQLP-SAGPDKNLVTGDHIPTPQDLPQRKSS----------------LVT--SKLAGGQVE---------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A2BF67-1", "uniprot_id": "A2BF67_DANRE", "id": "A2BF67-1", "name": "Alpha-endosulfine", "aln": "MSSDNQ--DTETHPEQVDET------QESQDTN-SNPVRTEEAKLKAKYPNLGQKPGG-SDFLMKRLQKGQKYFDSGDYNMAKAKMKNKQLPAAAGPDKNIVTGDHIPTPQDLPQRKSS----------------LVT--SKLAG-------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q1L8X2-1", "uniprot_id": "ENSA_DANRE", "id": "Q1L8X2-1", "name": "Alpha-endosulfine", "aln": "MSENPDDLELESEEKQCELKSGCVYLQDSPEKT-CNPILSEEAKLKAKYPSLGHKPGG-SDFLMKRLQKGQKYFDSGDYNMAKAKMKSKHVV-QSAAEKSLVTGDHIPTPQDLPQRKNT----------------ILT--SKLAG-------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VUB8-1", "uniprot_id": "Q9VUB8_DROME", "id": "Q9VUB8-1", "name": "", "aln": "MSSAEE--NSNSPATTPQDT------ETTEQANLTDLEKIEEEKLKSKYPSGMRVPGGHSAFLQKRLQKGQKFFDSGDYQMAKQKGGGVKQV----FANKVTTGEAIPTPETVPARKTS----------------IIQPCNKFPATS-----------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9P305-1", "uniprot_id": "IGO2_YEAST", "id": "Q9P305-1", "name": "mRNA stability protein IGO2", "aln": "MS-EDLSPTSSRVDLSNPHG-------FTKEGVDLSKLSPQELKLYKMY---GKLPSK-KDLLRHKMQD-RQYFDSGDYALKKAGVIKSDDVIVNNSSNNLPVTNPSGLRESIIRRRMSSSSGGDS----------ISRQGSISSGPPP----------------------------RSPNK", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P53897-1", "uniprot_id": "IGO1_YEAST", "id": "P53897-1", "name": "mRNA stability protein IGO1", "aln": "MSNENLSPNSSNPDLTKLNN-------GESGTIDTSKFSPNEMKLYKMY---GKLPSK-KDIFKHTMQK-RKYFDSGDYALQKAGIQNND--PINYGKNNLPLTNPSKLREDIIKRRISTCPSTASTAGVVDNATLIQKEGSISSGPPSSNNGTIGGGSTSSTPVGNHSSSSSSLYTESPIR", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "** . :* ** * : *. . :: : :*. :::****** : * . :.: : : : *: : : ..:.. ", "identical_positions": 16, "similar_positions": 29, "identity": "8.79%" }, { "cls_id": "homologset.agr.MGI:1891190", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9WUU7-1", "uniprot_id": "CATZ_MOUSE", "id": "Q9WUU7-1", "name": "Cathepsin Z", "aln": "MASSGSVQQLPLVLLMLLLASAARARLYFRSGQTCYHPIRGDQLALLGRRTYPRPHEYLSPADLPKNWDWRNVNGVNYASVTRNQHIPQYCGSCWAHGSTSAMADRINIKRKGAWPSILLSVQNVIDCGNAGSCEGGNDLPVWEYAHKHGIPDETCNNYQAKDQDCDKFNQCGTCTEFKECHTIQNYTLWRVGDYGSLSGREKMMAEIYANGPISCGIMATEMMSNYTGGIYAEHQDQAVINHIISVAGWGVSNDGIEYWIVRNSWGEPWGEKGWMRIVTSTYKGGTGDSYNLAIESACTFGDPIV", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9R1T3-1", "uniprot_id": "CATZ_RAT", "id": "Q9R1T3-1", "name": "Cathepsin Z", "aln": "MASSGSVQQLRLVLLMLLLAGAARASLYFRPGQTCYRPLHRDHLALLGRRTYPRPHEYLSPADLPKNWDWRNVNGVNYASVTRNQHIPQYCGSCWAHGSTSALADRINIKRKGAWPSTLLSVQNVIDCGNAGSCEGGNDLPVWEYAHKHGIPDETCNNYQAKDQECDKFNQCGTCTEFKECHTIQNYTLWRVGDYGSLSGREKMMAEIYANGPISCGIMATERMSNYTGGIYTEYQNQAIINHIISVAGWGVSNDGIEYWIVRNSWGEPWGERGWMRIVTSTYKGGTGSSYNLAIEEACTFGDPIV", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9UBR2-1", "uniprot_id": "CATZ_HUMAN", "id": "Q9UBR2-1", "name": "Cathepsin Z", "aln": "MARRG--PGWRPLLLLVLLAGAAQGGLYFRRGQTCYRPLRGDGLAPLGRSTYPRPHEYLSPADLPKSWDWRNVDGVNYASITRNQHIPQYCGSCWAHASTSAMADRINIKRKGAWPSTLLSVQNVIDCGNAGSCEGGNDLSVWDYAHQHGIPDETCNNYQAKDQECDKFNQCGTCNEFKECHAIRNYTLWRVGDYGSLSGREKMMAEIYANGPISCGIMATERLANYTGGIYAEYQDTTYINHVVSVAGWGIS-DGTEYWIVRNSWGEPWGERGWLRIVTSTYKDGKGARYNLAIEEHCTFGDPIV", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "** * :**::***.**:. **** *****:*:: * ** *** ****************.******:******:****************.****:************** **********************.**:***:****************:**********.******:*:************************************* ::*******:*:*: : ***::******:* ** ***************:**:********.*.* ******. ********", "identical_positions": 247, "similar_positions": 35, "identity": "80.72%" }, { "cls_id": "homologset.agr.MGI:1891198", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q14590-1", "uniprot_id": "ZN235_HUMAN", "id": "Q14590-1", "name": "Zinc finger protein 235", "aln": "MTKFQEAVTFKDVAVAFTEEELGLLDSAQRKLYRDVMLENFRNLVSVGHQSFKPDMISQLEREEKLWMKELQTQRGKHSGDRNQNEMATLHKAGLRCFSLGELSCWQIKRHIASKLARSQDSMINIEGKSSQFPKHHDSPCQVGAGESIQASVDDNCLVNHIGDHSSIIENQEFPTGKVPNSWSKIYLNETQNYQRSCKQTQMKNKLCIFAPYVDIFSCISHHHDDNIVHKRDKVHSNSDCGKDTLKVSPLTQRSIHTGQKTYQGNECEEAFNDSSSLELHKQVHLGKKSPACSTHEKDTSYSSGIPVQQSVRTGKKRYWCHECGKGFSQSSNLQTHQRVHTGEKPYTCHECGKSFNQSSHLYAHLPIHTGEKPYRCDSCGKGFSRSTDLNIHCRVHTGEKPYKCEVCGKGFTQRSHLQAHERIHTGEKPYKCGDCGKRFSCSSNLHTHQRVHTEEKPYKCDECGKCFSLSFNLHSHQRVHTGEKPYKCEECGKGFSSASSFQSHQRVHTGEKPFRCNVCGKGFSQSSYFQAHQRVHTGEKPYKCEVCGKRFNWSLNLHNHQRVHTGEKPYKCEECGKGFSQASNLQAHQSVHTGEKPFKCDACQKRFSQASHLQAHQRVHTGEKPYKCDTCGKAFSQRSNLQVHQIIHTGEKPFKCEECGKEFSWSAGLSAHQRVHTGEKPYTCQQCGKGFSQASHFHTHQRVHTGERPYICDVCCKGFSQRSHLIYHQRVHTGGNL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "E9Q8I5-1", "uniprot_id": "E9Q8I5_MOUSE", "id": "E9Q8I5-1", "name": "", "aln": "MTRKQEAVTFRDVAVVFSKEELGLLDAAQRKLYHDVMLENFRNLLAVGGQ--------------------------------SPNKIETLHAMGVRCLSLERLPCWQMTSHDVNKLARTPEDGINTQGKGS----HFLEPCHKGAEKPPWASEDDGCLERLTSNHSGITESQEFLSGGAQSSSSKSHPSERHDQWKHCPQTWVKNKAQLSALSADVLSCISHQ-DNNILHKRDKVPSSGDCDQVINPMSSLTQDCDYTQQKAYQCSKGQEVFSDSPSLELHQQTLLGKKSPVHSTH-KDTRQSPSVLIQPSVHLGTKRYWCHECGKGFSHSSTLQTHQRVHTGEK----------------------------PYRCDSCGKGFSRSSDLNIHRRVHTGEKLYKCEVCGKGFTKWDHLQIHERIHTGEKPYKCGDCGKRFSCSWNLHTHQRVHTEEKPYECNECGKRFSLSFNLHSHQRVHTGEKPYKCEECGKDFSSASSFQRHQRVHTGEKPFVCSVCGKGFSQSSNFQAHQRVHTREKPYRCDVCGKHFTWSL--HNHQRVHTGEKPYMCVECGKGFSHASSLQAHQSVHTGERPFKCNVCQKRFRQASILQDHERVHTGEKPYKCDTCGKVFSQRSGLQVHQRIHTGEKPFKCEECGKEFRWNSGLSSHQRVHTAEKPYMCQQCGKGFSQASHFHTHLKMHTTERI----------------------------", "tax_id": 10090, "tax_name": "Mouse" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "**: ******:****.*::*******:******:**********::** * . *:: *** *:**:** .*.***:. * ..****: :. ** :**.* *. .**: ** :. ** **.** . .:**.* *.*** :* . .* ** : .* :: : * ** :*** : * .*::*****: *:**:****** *..**.: :*.*** . :* **:** .: :*.*.**.*****:*. ******. *** *** *..: :* **: *.*************:**.************ **************:***** ******* ***********: .*** *********************** ***************:*:**** ***************************.******** *********** *.********** ********* ****:*:****:*.*** ************* * *******:**.***********:****:.***** *** ** *:****************.*****.***** ***************** *.:***:******.**** ***************** ::** ** ", "identical_positions": 462, "similar_positions": 103, "identity": "62.6%" }, { "cls_id": "homologset.agr.MGI:1891207", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I5YBG7-1", "uniprot_id": "A0A8I5YBG7_RAT", "id": "A0A8I5YBG7-1", "name": "Pyridoxal phosphate homeostasis protein", "aln": "MLRGGSMTAELGVGLALRAVNERVQQSVARRPR----GLPAIQPRLVAVSKTKPTEMVIEAYGHGQRTFGENYVQELLEKASNPTLLSSCPEIKWHFIGHLQKQNVNKLMAVPNLSMLETIDSVKLADKVNSSWQKKGSP--ERLKVMVQINTSGEDSKHGLL-PSETVAVVEHIK-ASCPNLEFVGLMTIGSFGHDLSQG-PNPDFQRLLSLRQELCEKLGLPVEQVELSMGMSVDFQHAIEVGSTNIRVGSTIFGERDYSKKPAPDKTTIDLTASVPLVQGQ", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9Z2Y8-1", "uniprot_id": "PLPHP_MOUSE", "id": "Q9Z2Y8-1", "name": "Pyridoxal phosphate homeostasis protein", "aln": "MLRGGSMTAELGVGFALRAVNERVQQSVARRPR----DLPAIQPRLVAVSKTKPADMVIEAYGHGQRTFGENYVQELLEKASNPKILSSCPEIKWHFIGHLQKQNVNKLMAVPNLSMLETVDSVKLADKVNSSWQKKGPT--EPLKVMVQINTSGEDSKHGLL-PSETIAVVEHIK-ASCPSLEFVGLMTIGSFGHDLSQG-PNPDFQRLLTLRRELCEKLGIPVEQVELSMGMSMDFQHAIEVGSTNVRIGSTIFGERDYSKKPALDKT-ADAKASVPLVQGH", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O94903-1", "uniprot_id": "PLPHP_HUMAN", "id": "O94903-1", "name": "Pyridoxal phosphate homeostasis protein", "aln": "MWRAGSMSAELGVGCALRAVNERVQQAVARRPR----DLPAIQPRLVAVSKTKPADMVIEAYGHGQRTFGENYVQELLEKASNPKILSLCPEIKWHFIGHLQKQNVNKLMAVPNLFMLETVDSVKLADKVNSSWQRKGSP--ERLKVMVQINTSGEESKHGLP-PSETIAIVEHIN-AKCPNLEFVGLMTIGSFGHDLSQG-PNPDFQLLLSLREELCKKLNIPADQVELSMGMSADFQHAVEVGSTNVRIGSTIFGERDYSKKPTPDKCAADVKAPLEVAQEH", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VA97-1", "uniprot_id": "Q9VA97_DROME", "id": "Q9VA97-1", "name": "Pyridoxal phosphate homeostasis protein", "aln": "MLR--RTMAEFDVKAGLQHVLKRIDEVLLQRPK----EVQAARPLLVAVSKTKPAEAVIEAYEGGQRDFGENYVQELEEKSRHPDILAKCPDIRWHFIGHMQSNKINKILSVPNLHMIQTVDSEKLATKLDAAWSKRQPTPEEPLQVLIQINTSGEDVKSGIE-AKDAPALYQYIK-SNLKHLNLMGIMTIGAFGFDYSNG-PNPDFVSLMQVHRSICEAHSLAPDSVLVSMGMSNDFDKAIEMGSTVVRVGSSIFGHR---------------AAKV------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P38197-1", "uniprot_id": "PLPHP_YEAST", "id": "P38197-1", "name": "Pyridoxal phosphate homeostasis protein", "aln": "MSTG--ITYDEDRKTQLIAQYESVREVVNAEAKNVHVNENASKILLLVVSKLKPASDIQILYDHGVREFGENYVQELIEKAK---LLP--DDIKWHFIGGLQTNKCKDLAKVPNLYSVETIDSLKKAKKLNESRAKFQPD-CNPILCNVQINTSHEDQKSGLNNEAEIFEVIDFFLSEECKYIKLNGLMTIGSWNVSHEDSKENRDFATLVEWKKKIDAKFGT---SLKLSMGMSADFREAIRQGTAEVRIGTDIFGARPPKN-----------EARII-----", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* : . * : : : : ..: * : *:.*** **:. : * * * ********* **: :*. :*:***** :*.:: :.: **** ::*:** * * *:: : : . : : :***** *: * *: : : :.: . ::: *:****::. . .:. * ** *: :..: . .: :***** ** .*:. *:: :*:*: *** * * : ", "identical_positions": 74, "similar_positions": 75, "identity": "26.06%" }, { "cls_id": "homologset.agr.MGI:1891209", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I5Y8F2-1", "uniprot_id": "A0A8I5Y8F2_RAT", "id": "A0A8I5Y8F2-1", "name": "EGF-containing fibulin-like extracellular matrix protein 2", "aln": "MLPFASCLPGSLLLWAFLLLLLGAASPQDSEEPDSYTECTDGYEWDADSQHCRDVNECLTIPEACKGEMKCINHYGGYLCLPRSAAVISDLHSEGPPPPAASAQHPNPCPPGYEPDEQESCVDVDECTQAIHDCRPSQDCHNLPGSYQCTCPDGYRKIGPECVDIDECRYRYCQHRCVNLPGSFRCQCEPGFQLGPNNRSCVDVNECDMGAPCEQRCFNSYGTFLCRCNQGYELHRDGFSCSDIDECSYSSYLCQYRCVNEPGRFSCHCPQGYQLLATRLCQDIDECETGAHQCSEAQTCVNFHGGYRCVDTNRCVEPYVQVSDNRCLCPASNPLCREQPSSIVHRYMSITSERSVPADVFQIQATSVYPGAYNAFQIRAGNTQGDFYIRQINNVSAMLVLARPVTGPREYVLDLEMVTMNSLMSYRASSVLRLTVFVGAYTF", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9WVJ9-1", "uniprot_id": "FBLN4_MOUSE", "id": "Q9WVJ9-1", "name": "EGF-containing fibulin-like extracellular matrix protein 2", "aln": "MLPFASCLPGSLLLWAFLLLLLGAASPQDPEEPDSYTECTDGYEWDADSQHCRDVNECLTIPEACKGEMKCINHYGGYLCLPRSAAVISDLHGEGPPPPAAHAQQPNPCPQGYEPDEQESCVDVDECTQALHDCRPSQDCHNLPGSYQCTCPDGYRKIGPECVDIDECRYRYCQHRCVNLPGSFRCQCEPGFQLGPNNRSCVDVNECDMGAPCEQRCFNSYGTFLCRCNQGYELHRDGFSCSDIDECGYSSYLCQYRCVNEPGRFSCHCPQGYQLLATRLCQDIDECETGAHQCSEAQTCVNFHGGYRCVDTNRCVEPYVQVSDNRCLCPASNPLCREQPSSIVHRYMSITSERSVPADVFQIQATSVYPGAYNAFQIRSGNTQGDFYIRQINNVSAMLVLARPVTGPREYVLDLEMVTMNSLMSYRASSVLRLTVFVGAYTF", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O95967-1", "uniprot_id": "FBLN4_HUMAN", "id": "O95967-1", "name": "EGF-containing fibulin-like extracellular matrix protein 2", "aln": "MLPCASCLPGSLLLWALLLLLLGSASPQDSEEPDSYTECTDGYEWDPDSQHCRDVNECLTIPEACKGEMKCINHYGGYLCLPRSAAVINDLHGEGPPPPVPPAQHPNPCPPGYEPDDQDSCVDVDECAQALHDCRPSQDCHNLPGSYQCTCPDGYRKIGPECVDIDECRYRYCQHRCVNLPGSFRCQCEPGFQLGPNNRSCVDVNECDMGAPCEQRCFNSYGTFLCRCHQGYELHRDGFSCSDIDECSYSSYLCQYRCINEPGRFSCHCPQGYQLLATRLCQDIDECESGAHQCSEAQTCVNFHGGYRCVDTNRCVEPYIQVSENRCLCPASNPLCREQPSSIVHRYMTITSERSVPADVFQIQATSVYPGAYNAFQIRAGNSQGDFYIRQINNVSAMLVLARPVTGPREYVLDLEMVTMNSLMSYRASSVLRLTVFVGAYTF", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*** ************:******:*****.****************.*****************************************.***.******.. **:***** *****:*:********:**:*************************************************************************************************:******************.**********:*****************************:******************************:***:************************:******************************:**:************************************************************", "identical_positions": 418, "similar_positions": 22, "identity": "94.36%" }, { "cls_id": "homologset.agr.MGI:1891214", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q80SV1-1", "uniprot_id": "LHPL1_MOUSE", "id": "Q80SV1-1", "name": "LHFPL tetraspan subfamily member 1 protein", "aln": "MRNSLTMVGTFWAFLSLVTAVASSTSYFLPYWLFGSQLGKPVSFSTFRRCNYPVRGDGHNLIMVEECGRYASFTAIPSLAWQMCTVVTGAGCALLLLVALAAVLGCCMEELISRMMGRCMGAAQFVGGLLISAGCALYPLGWNSPEVMQTCGNVSNQFQLGTCRLGWAYYCAGGGAAAAMLICTWLSCFAGRNPKPVMLVENIMRNTNSYALELDHCLKP", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q80WE5-1", "uniprot_id": "LHPL1_RAT", "id": "Q80WE5-1", "name": "LHFPL tetraspan subfamily member 1 protein", "aln": "MRSSLTLVGTFWAFLSLVTAVASSTSYFLPYWLFGSQLGKPVSFSTFRRCNYPVRGDGHNLIMVEECGRYASFAAIPSLAWQMCTVVTGAGCALLLLVALAAVLGCCMEELISRMMGRCMGAAQFVGGLLISSGCALYPLGWNSPEVMQTCGNVSNQFQLGTCRLGWAYYCAGGGAAAAMLICTWLSCFAGRNPKPVMLVENIMRNTNSYAMELDHCLKP", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q86WI0-1", "uniprot_id": "LHPL1_HUMAN", "id": "Q86WI0-1", "name": "LHFPL tetraspan subfamily member 1 protein", "aln": "MRSSLTMVGTLWAFLSLVTAVTSSTSYFLPYWLFGSQMGKPVSFSTFRRCNYPVRGEGHSLIMVEECGRYASFNAIPSLAWQMCTVVTGAGCALLLLVALAAVLGCCMEELISRMMGRCMGAAQFVGGLLISSGCALYPLGWNSPEIMQTCGNVSNQFQLGTCRLGWAYYCAGGGAAAAMLICTWLSCFAGRNPKPVILVESIMRNTNSYAMELDHCLKP", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "**.***:***:**********:***************:******************:**.************* **********************************************************:*************:**************************************************:***.*********:********", "identical_positions": 207, "similar_positions": 12, "identity": "94.09%" }, { "cls_id": "homologset.agr.MGI:1891217", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O08961-1", "uniprot_id": "ZN423_RAT", "id": "O08961-1", "name": "Zinc finger protein 423", "aln": "----MSRRKQAKPRSVK-VEEGEASDFSLAWDSSVAAAGGLEGESECDRKSSRALED--RNSVTSQEERNEDDEDVEDESIYTCDHCQQDFESLADLTDHRAHRCPGDGDDDPQLSWVASSPSSKDVASPTQMIGDG-CDLGLG--EEEGGTGLPYPCQFCDKSFIRLSYLKRHEQIHSDKLPFKCTFCSRLFKHKRSRDRHIKLHTGDKKYHCHECEAAFSRRDHLKIHLKTHSSSKPFKCSVCKRGFSSTSSLQSHMQAHKKNKEHLAKSEK-----------EAKKDDFMCDYCEDTFSQTEELEKHVLTLHPQLSEKADLQCIHCPEVFVDESTLLAHIHQAHANQKHKCPMCPEQFSSVEGVYCHLDSHRQPDSSNHSVSPDPVLGSVASMSSATPDSTPDPVLGSVASMSSATPDSSASVERGSTPDSTLKPLRGQKKMR-----DDGQSWSKVVYSCPYCSKR-DFTSLAVLEIHLKTIHADKPQQSHTCQICLDSMPTLYNLNEHVRKLHKS-----HAYPVMQFGNISAFHCNYCPEMFADINSLQEHIRVSHCGPN-----ANPPDGNNAFFCNQCSMGFLTESSLTEHIQQAHCS-VG-STKLESPVIQPTQSFMEVYSCPYCTNSPIFGSILKLTKHIKENHKNIPLAHSKK--SKAEQSPVSSDVEVSSPKRQRLSGSAN-SISNGEYPCNQCDLKFSNFESFQTHLKLHLELLLRKQACPQC-KEDFDSQESLLQHLTVHYMTTSTHYVCES-CDKQFSSVDDLQKHLLDMHTFVLYHCTLCQEVFDSKVSIQVHLAVKHSNEKKMYRCTACNWDFRKEADLQVHVKHSHLGN-----------PAKAHKCIFCGETFSTEVELQCHITTHSKKYNCRFCSKAFHAVLLLEKHLREKH-------------------------------------------------CVFD-------PAAENGTANGVPPTS----------------TKKAEPADLQGMLLK--NPEAPNSHEAS--EDDVDASEPMYGCDICG-AAYTMEVLLQNHRLRDHNIRPGEDDGS--RKKAEFIKG--SHKCNVCSRTFFSENGLREHLQTHRGPAKHYMCPICGERFPSLLTLTEHKVTHSKSLDTGTCRICKMPLQSEEEFIEHCQMHPDLRNSLTGFRCVVCMQTVTSTLELKIHGTFHMQKLAGS--------SAASSPNGQ-GLQKLYKCALCLKEFRSKQDLVRLDVNGLPYGLCAGCMARS-ANGQVG----GLAPPEPADRPCAGLRCPECNVKFESAEDLESHMQVDHRDLTPETSGPRKGAQTSPVPRKKTYQCIKCQMTFENEREIQIHVANHMIEEGINHECK---LCNQMFDSPAKLLCHLIEHSFEGMGGTFKCPVCFTVFVQANKLQQH----IFAVHGQEDKIYDCSQCPQKFFFQTELQNHTMSQHAQ", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q80TS5-1", "uniprot_id": "ZN423_MOUSE", "id": "Q80TS5-1", "name": "Zinc finger protein 423", "aln": "----MSRRKQAKPRSVK-VEEGEASDFSLAWDSSVAAAGGLEGEPECDRKTSRALED--RNSVTSQEERNEDDEDVEDESIYTCDHCQQDFESLADLTDHRAHRCPGDGDDDPQLSWVASSPSSKDVASPTQMIGDG-CDLGLG--EEEGGTGLPYPCQFCDKSFIRLSYLKRHEQIHSDKLPFKCTFCSRLFKHKRSRDRHIKLHTGDKKYHCHECEAAFSRSDHLKIHLKTHSSSKPFKCSVCKRGFSSTSSLQSHMQAHKKNKEHLAKSEK-----------EAKKDDFMCDYCEDTFSQTEELEKHVLTLHPQLSEKADLQCIHCPEVFVDESTLLAHIHQAHANQKHKCPMCPEQFSSVEGVYCHLDSHRQPDSSNHSVSPDPVLG-------------------SVASMSSATPDSSASVERGSTPDSTLKPLRGQKKMR-----DDGQSWPKVVYSCPYCSKR-DFTSLAVLEIHLKTIHADKPQQSHTCQICLDSMPTLYNLNEHVRKLHKS-----HAYPVMQFGNISAFHCNYCPEMFADINSLQEHIRVSHCGPN-----ANPPDGNNAFFCNQCSMGFLTESSLTEHIQQAHCS-VG-STKLESPVVQPTQSFMEVYSCPYCTNSPIFGSILKLTKHIKENHKNIPLAHSKK--SKAEQSPVSSDVEVSSPKRQRLSGSAN-SISNGEYPCNQCDLKFSNFESFQTHLKLHLELLLRKQACPQC-KEDFDSQESLLQHLTVHYMTTSTHYVCES-CDKQFSSVDDLQKHLLDMHTFVLYHCTLCQEVFDSKVSIQVHLAVKHSNEKKMYRCTACNWDFRKEADLQVHVKHSHLGN-----------PAKAHKCIFCGETFSTEVELQCHITTHSKKYNCRFCSKAFHAVILLEKHLREKH-------------------------------------------------CVFD-------AAAENGTANGVPPTS----------------TKKAEPADLQGMLLK--NPEAPNSHEAS--EDDVDASEPMYGCDICG-AAYTMEVLLQNHRLRDHNIRPGEDDGS--RKKAEFIKG--SHKCNVCSRTFFSENGLREHLQTHRGPAKHYMCPICGERFPSLLTLTEHKVTHSKSLDTGTCRICKMPLQSEEEFIEHCQMHPDLRNSLTGFRCVVCMQTVTSTLELKIHGTFHMQKLAGS--------SAASSPNGQ-GLQKLYKCALCLKEFRSKQDLVRLDVNGLPYGLCAGCMARS-ANGQVG----GLAPPEPADRPCAGLRCPECNVKFESAEDLESHMQVDHRDLTPETSGPRKGAQTSPVPRKKTYQCIKCQMTFENEREIQIHVANHMIEEGINHECK---LCNQMFDSPAKLLCHLIEHSFEGMGGTFKCPVCFTVFVQANKLQQH----IFAVHGQEDKIYDCSQCPQKFFFQTELQNHTMSQHAQ", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q2M1K9-1", "uniprot_id": "ZN423_HUMAN", "id": "Q2M1K9-1", "name": "Zinc finger protein 423", "aln": "----MHKKR---------VEEGEASDFSLAWDSSVTAAGGLEGEPECDQKTSRALED--RNSVTSQEERNEDDEDMEDESIYTCDHCQQDFESLADLTDHRAHRCPGDGDDDPQLSWVASSPSSKDVASPTQMIGDG-CDLGLG--EEEGGTGLPYPCQFCDKSFIRLSYLKRHEQIHSDKLPFKCTYCSRLFKHKRSRDRHIKLHTGDKKYHCHECEAAFSRSDHLKIHLKTHSSSKPFKCTVCKRGFSSTSSLQSHMQAHKKNKEHLAKSEK-----------EAKKDDFMCDYCEDTFSQTEELEKHVLTRHPQLSEKADLQCIHCPEVFVDENTLLAHIHQAHANQKHKCPMCPEQFSSVEGVYCHLDSHRQPDSSNHSVSPDPVLG-------------------SVASMSSATPDSSASVERGSTPDSTLKPLRGQKKMR-----DDGQGWTKVVYSCPYCSKR-DFNSLAVLEIHLKTIHADKPQQSHTCQICLDSMPTLYNLNEHVRKLHKN-----HAYPVMQFGNISAFHCNYCPEMFADINSLQEHIRVSHCGPN-----ANPSDGNNAFFCNQCSMGFLTESSLTEHIQQAHCS-VG-SAKLESPVVQPTQSFMEVYSCPYCTNSPIFGSILKLTKHIKENHKNIPLAHSKK--SKAEQSPVSSDVEVSSPKRQRLSASAN-SISNGEYPCNQCDLKFSNFESFQTHLKLHLELLLRKQACPQC-KEDFDSQESLLQHLTVHYMTTSTHYVCES-CDKQFSSVDDLQKHLLDMHTFVLYHCTLCQEVFDSKVSIQVHLAVKHSNEKKMYRCTACNWDFRKEADLQVHVKHSHLGN-----------PAKAHKCIFCGETFSTEVELQCHITTHSKKYNCKFCSKAFHAIILLEKHLREKH-------------------------------------------------CVFD-------AATENGTANGVPPMA----------------TKKAEPADLQGMLLK--NPEAPNSHEAS--EDDVDASEPMYGCDICG-AAYTMEVLLQNHRLRDHNIRPGEDDGS--RKKAEFIKG--SHKCNVCSRTFFSENGLREHLQTHRGPAKHYMCPICGERFPSLLTLTEHKVTHSKSLDTGTCRICKMPLQSEEEFIEHCQMHPDLRNSLTGFRCVVCMQTVTSTLELKIHGTFHMQKLAGS--------SAASSPNGQ-GLQKLYKCALCLKEFRSKQDLVKLDVNGLPYGLCAGCMARS-ANGQVG----GLAPPEPADRPCAGLRCPECSVKFESAEDLESHMQVDHRDLTPETSGPRKGTQTSPVPRKKTYQCIKCQMTFENEREIQIHVANHMIEEGINHECK---LCNQMFDSPAKLLCHLIEHSFEGMGGTFKCPVCFTVFVQANKLQQH----IFAVHGQEDKIYDCSQCPQKFFFQTELQNHTMSQHAQ", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A1L1R6-1", "uniprot_id": "ZN423_DANRE", "id": "A1L1R6-1", "name": "Zinc finger protein 423", "aln": "----MSRRKQAKPRSVKAVEEAESTECASGWDSSVQTDAAVS-ERDSDRKESRAVGEDGEQSVTSHDER-VGEEDLDDDSIFTCDNCQQDFECLADLTEHRTNHCPADGDDDPGLSWVASSPSSKDVASPSQMLGDGCCDMGMGTGEEEGGSGLPYPCQFCDKSFSRLSYLKRHEQIHSDKLPFKCTFCSRLFKHKRSRDRHVKLHTGDKKYSCQECEAAFSRSDHLKIHLKTHSSSKPFKCSICKRGFSSTSSLQSHMQAHRKNKEHLAKKDQGKRDGSSSDVTEQDQDLYMCDYCEETFSQTDELEKHVLTQHPQLSDRAELQCIHCPEIFSDEGTLLTHIDRTHANKKHKCPMCAEQFPSVEDVYCHLDSHRQPDSSNHSASPDPVLG-------------------SVASMSSATPDSSASLERGSTPDSTLKPGQSRRKLAPSSDHDDGTWSGKVTYSCPYCSKR-DFNSLAVLEIHLKTIHADKPQQSHTCQLCLETLPTLYNLNEHVRKAHRSSGNSASNFPLLQFSNVSAFHCNYCPDMFADINSLQEHIRVSHCLSGGVVAGSTTLEGNHAFFCNQCSMGFLTESSLTEHIQQTHCSSVGGVTKMESPVLQPSQSFMEVYSCPYCTNSPIFGSLLKLTKHIKENHKNIPLANNKRKVKVADLSPASSDVEISSPKRHRVTGDSTPAVANGDYPCNQCDLRFSSFEGFQAHLKSHLELLLRRQSCPQCNKEDFDSQEALLQHLTIHYTTTSTQYVCES-CDKQFSSVDDLQKHLLDMHTFVLYHCTLCQEVFDSKVSIQVHLAVKHSNEKKMYRCTACAWDFRKESDLQLHVKHSHLGHPASTG-----APGKARKCIFCGETFGTEVELQCHITTHSKKYNCRLCGKAFHAIVLLERHLREKH-------------------------------------------------CIFDGGNGNGNGGSQNGTPNGVTQSSKRSTA---------GSTAAAEQADLQNMLLKGGSQETANSHEASGGEEELDASEPMYACDICG-AAYTMESLLQNHRLRDHNIRPGEDDAGSRKKKADFIKG--NHKCNVCSRTFFSENGLREHAQTHRGPAKHYMCPICGERFPSLLTLTEHKVTHSKSLDTGTCRICKMPLQSEEEFIEHCQMHPDLRNSLTGFRCVVCMQTVTSTLELKIHGTFHMQKLSSSGGSGGGGGSASSSPNGQLQAHKLYKCALCLKDFKNKQELVKIDVNGLPYGLCAGCMSRG-TNGQSPTV--VVTPQEAGDKGTTGLRCSECAVKFETLEDLESHIQVDHTEMSPETSGAKKVTDASPVPKKKTYQCIKCQMTFETEREIQIHVANHMIEEGINHECK---LCNQMFDSPAKLLCHLIEHSFEGMGGTFKCPVCFTVFVQANKLQQH----IFAVHGQEDKIYDCSQCPQKFFFQTELQNHTLSQHAQ", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A1Z9R4-1", "uniprot_id": "ZN423_DROME", "id": "A1Z9R4-1", "name": "Zinc finger protein 423 homolog", "aln": "MMALKMLYRGPSSRLENLIEKIQATKEITNNDMYSTHTSSSYSPSISDGTMTPNSHHLIGAPTAAGQEDHPTEGKINGGADGEDLPKPKRLPHFHHHHHHHYHHQQALKIAN-KLRKINKEAKMGATAGGGATGAASKFDKLTGEGIKSRGDGS-YQCQFCEKTFPRLGYLKHHVQSHAEHLPFKCEYCSKLFKHKRSRDRHKKLHTNERNYKCPHCEAAFSRSDHLKIHMKTHDIQKPFQCSMCNRGYNTAAALTSHMQKHKKNAAILAAGGN-------------------------------------------------------------------------PNALNYSPRSTGSASASVSSNGSLQKRRYALALASDSSP---------------------------SRMDFPKRSRSNHVGGTTTTATPTP----------------------LLRCSYCPKVTEFSSLEQLNAHLQSVHEQPQTQAVKTPVQE--------------------------------GEGFQLSCEYCTMKFGNIAGLFQHMRSTHMDRLS------SPNSYYEHFNRLATAGTFSPR-----------------LALDLPKIKPDLGSPERESRP------------------AEDDLPTDLSNNKR-------RPLTPNPQAQTP-------LAPPSAPPGVFFCNQCNAGLPDFESFRNHLKSHIAEGMQ-LVCPHC-GMSLPEQSEFERHVVGHFLITGSEFNCSSSCGKSFAKSEDLQQHLLSEHVLTLLKCSLCSELCESRMAMQLHLACAHSQETKLLRCSACLELFRSDAEFHVHVKTRHQLGGHPTLGATSSAPTNPLQCMFCRAVCSSELEMHFHLAAHARQFRCPSCPETFHVEFLLDRHMQSQHGGVKDKEANSPNMGSLYVNALLPPLAAAAAAAAATNNNSSIIDYNVAFKGLFGGASGGAGSGGGGAQSGGAPPSANKFYSPLQVDTNALKAQTSPHPALMYGLSQRYLMEMYAAKSTSPSGNEGVGNSQPPAPQATAPPPPPNASTATFSCGMCERQDLRSEAELHSHRKLAHNLKTGVSLRCAYCAGNFKSRAELEQHMKSCHNSTGKHKCLICDEVFPSPAILAEHKLQHSKVGQSGKCSHCGQPLEDVAAFRAHLSEHGSDGASLP-LACICCRQTLHSEFELSLHAKFHTKSSSSG------------------GSLQEPVCALCLEPLP--------DATEGPAKLCDKCCRKHNLNGKRGKHSEPATSLPAPPSAFVENRCNLCKMILPHAQKLQEHLVEHTFAGTEQRGFNCYICSAVFTAPGGLLNHMGEHGAHSRPYDCNLCPEKFFFRAELEHHQRGHELRPQARPPAAKVEVPSIRNTSPGQSPVRSPTIVKQELYETDTVESAGVEDEPENHPDEEEYIEVEQMPHETRPSGIGSQLERSTSSA", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : :*: :::. * .. .* . : . ..:: :* : .::. : : : : . .*: :: . : * : .... .*. . . * * :. * * * ****:*:* **.***:* * *:::***** :**:*********** ****.:::* * .******* ******:***. .***:*::*:**:.::::* **** *:** ** : .* : .* .. . .: . *:.:* . : . ** * . . * :. *:*. :* .* *.**.* :*.** *: **:::* : *: . : .: : *:**. *.:* .* :*:* :* . :. .* . .: * :: :: * ::* . * * * *:. *::.*: * :.: : .:* : : . * : ****: :..**.*: *** *: :: **:* .: .*. : :*:. *: *.:.: *.* *.*.*:. :***:***. *.:.* :*:**.*: :*::::*:*** **:*.*: **:** **.::::::*** * * :. :*:** . .:*:*:: *:::*::::.* * ::**. .**::*::.:* :*. . .. ..*.. : .. * : .: : . . :. :: :. *:* . .. . . . : ::: .* : :* *. :* . :* *: .* *. *.:* :: :..: :: * **.* *** *:***: *** ::*.* * **:. * * . * . **. : *: * **: * :**.:*..** :. :.. : *****: : *.. * ** * : **: :. . . ** * : : :.*:.*: . : : . .: .. : : : :.. : :: :.::. ::*. : * * ..**: *.:: * . . . .: : :::.::. * :*:: : .* *:: . .: * : ", "identical_positions": 277, "similar_positions": 386, "identity": "18.87%" }, { "cls_id": "homologset.agr.MGI:1891221", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A096MK61-1", "uniprot_id": "A0A096MK61_RAT", "id": "A0A096MK61-1", "name": "", "aln": "MGP-RSPAAALLVLLCAGCVLSPGRAQYERYSFRSFPRDELMPLESAYRHALDQYSGEHWAESVGYLEVSLRLHRLLRDSEAFCHRNCSAATPAPAPSGPASPASHRELRLFGGVLRRAQCLKRCKQGLPAFRQSQPSRAVLADFQQREPYKFLQFAYFKANDLPKAIAAAHTYLLKHPEDEMMKRNMEYYKSLPGAEDHIKDLETKSYESLFVRAVRAYNGENWRTSISDMELALPDFFKAFYECLAACEGSREIKDFKDFYLSIADHYVEVLECKIHCEETLTPVIGGYPVEKFVATIYHYLQFAYYKLNDLKNAAPCAVSYLLFDPNDKVMQQNLVYYQYHRDKWGLSDEHFQPRLEAVQFFNVTTLQKELYDFAQEHLMDDDEGEVVEYVDDLLEMEESA", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9CYD3-1", "uniprot_id": "CRTAP_MOUSE", "id": "Q9CYD3-1", "name": "Cartilage-associated protein", "aln": "MGP-RSPTAALLVLLCVGCAPTPGRGQYERYSFRSFPRDELMPLESAYRHALDQYSGEHWAESVGYLEVSLRLHRLLRDSEAFCHRNCSAATPAPAPAG---PASHAELRLFGSVLRRAQCLKRCKQGLPAFRQSQPSRSVLADFQQREPYKFLQFAYFKANDLPKAIAAAHTYLLKHPDDEMMKRNMEYYKSLPGAEDHIKDLETKSYESLFVRAVRAYNGENWRTSISDMELALPDFLKAFYECLAACEGSREIKDFKDFYLSIADHYVEVLECKIRCEETLTPVIGGYPVEKFVATMYHYLQFAYYKLNDLKNAAPCAVSYLLFDQSDRVMQQNLVYYQYHRDKWGLSDEHFQPRPEAVQFFNVTTLQKELYDFAQEHLMDDDEGEVVEYVDDLLETEESA", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O75718-1", "uniprot_id": "CRTAP_HUMAN", "id": "O75718-1", "name": "Cartilage-associated protein", "aln": "MEPGRRGAAALLALLCVACALRAGRAQYERYSFRSFPRDELMPLESAYRHALDKYSGEHWAESVGYLEISLRLHRLLRDSEAFCHRNCSAAPQPEPAAG---LASYPELRLFGGLLRRAHCLKRCKQGLPAFRQSQPSREVLADFQRREPYKFLQFAYFKANNLPKAIAAAHTFLLKHPDDEMMKRNMAYYKSLPGAEDYIKDLETKSYESLFIRAVRAYNGENWRTSITDMELALPDFFKAFYECLAACEGSREIKDFKDFYLSIADHYVEVLECKIQCEENLTPVIGGYPVEKFVATMYHYLQFAYYKLNDLKNAAPCAVSYLLFDQNDKVMQQNLVYYQYHRDTWGLSDEHFQPRPEAVQFFNVTTLQKELYDFAKENIMDDDEGEVVEYVDDLLELEETS", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* * * :****.***..*. .**.***************************:**************:**********************. . ..:* **: ******.:****:******************* ******:***************:**********:*****:******** **********:*************:***************:*********:**************************************:***.****************:**************************** .*:**************.*********** *******************:*::***************** **::", "identical_positions": 349, "similar_positions": 37, "identity": "86.39%" }, { "cls_id": "homologset.agr.MGI:1891227", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O60869-1", "uniprot_id": "EDF1_HUMAN", "id": "O60869-1", "name": "Endothelial differentiation-related factor 1", "aln": "---------------------------------------------------MAESDWDTVT---------------VLRKK---GPTAAQAKSKQAILAAQRRGEDVETSK-KWAAGQNKQHSITKNTAKLDRETEELHHDRVTLEVGKVIQQGRQSKGLTQKDLATKINEKPQVIADYESGRAIPNNQVLGKIERAIGLKLRGKDIGKPIEKGPRAK------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9JMG1-1", "uniprot_id": "EDF1_MOUSE", "id": "Q9JMG1-1", "name": "Endothelial differentiation-related factor 1", "aln": "---------------------------------------------------MAESDWDTVT---------------VLRKK---GPTAAQAKSKQAILAAQRRGEDVETSK-KWAAGQNKQHSITKNTAKLDRETEELHHDRVTLEVGKVIQRGRQSKGLTQKDLATKINEKPQVIADYESGRAIPNNQVLGKIERAIGLKLRGKDIGKPIEKGPKAK------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0ABK0L496-1", "uniprot_id": "A0ABK0L496_RAT", "id": "A0ABK0L496-1", "name": "Endothelial differentiation-related factor 1", "aln": "MWRHPKNVGTQVSTCKARVCCGIACLMVWCGGTPGNCQEQRLGSQEIFLTCRHSSGWHEISGIVPSHLLPATVGRFRFRPRKMLGLACQSGVHLKSFPCADCKPHSVPLTLPAGAAGQNKQHSITKNTAKLDRETEELHHDRVTLEVGKVIQRGRQSKGLTQKDLATKINEKPQVIADYESGRAIPNNQVLGKIERAIGLKLRGKDIGKPIEKGPKAK------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q6PBY3-1", "uniprot_id": "EDF1_DANRE", "id": "Q6PBY3-1", "name": "Endothelial differentiation-related factor 1 homolog", "aln": "---------------------------------------------------MAECDWDTVT---------------VLRKK---GSAAQSK-SKQAVTAAQRKGEAVETSK-KWAAGQNKQHVVTKNTAKLDRETEELSHQRVPLEVGKVIQQGRQNKGLTQKDLATKINEKPQIIAEYECGKAIPNNQVMGKIERAIGLKLRGKDIGLPLEACSKK-------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "M9PFR6-1", "uniprot_id": "M9PFR6_DROME", "id": "M9PFR6-1", "name": "", "aln": "-----------------------------------------------------MSDWDSVT---------------VLRKK---APKSSTLKTESAVNQARRQGVAVDTQQ-KYGAGTNKQHVTTKNTAKLDRETEELRHDKIPLDVGKLIQQGRQSKGLSQKDLATKICEKQQVVTDYEAGRGIPNNLILGKMERVLGIKLRGKERGQPIAPPGKKXNDAAASAASGAPHTVTSGRSARQQNHQHTDSGGWSTVSGRRK", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "O14467-1", "uniprot_id": "MBF1_YEAST", "id": "O14467-1", "name": "Multiprotein-bridging factor 1", "aln": "-----------------------------------------------------MSDWDTNTIIG-----------SRARAGGS-GPRANVARSQGQINAARRQGLVVSVDK-KYGSTNTRGDNEGQRLTKVDRETDIVKPKKLDPNVGRAISRARTDKKMSQKDLATKINEKPTVVNDYEAARAIPNQQVLSKLERALGVKLRGNNIGSPLGAPKKK-------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ..*. : * . . . * : * .: .: . :. :*:****: : .:: :**: *.:.* .* ::******** ** :: :**..:.***: ::.*:**.:*:****:: * *: : ", "identical_positions": 39, "similar_positions": 49, "identity": "15.0%" }, { "cls_id": "homologset.agr.MGI:1891228", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "G3V921-1", "uniprot_id": "G3V921_RAT", "id": "G3V921-1", "name": "Sciellin", "aln": "MSNFSSRKKSPVGNDPKS-TQGAALRQQGFHDVNKRRAFLQDNSWIKKLPEE----EKDENYGRVVLSRHNSHDALDRKITERDEPKATISRYRSEDMLD-----------------------RSLSTFRTPESTKTPAGSSFSANTTAP----STPATTPVKKKRQSWFPPPPPGHNAPPSTGASRRDPPLHPPLPPKPCSPIASPKQLRQSHRQMHMATAGACG-EADRHAARNIRTEDLDDIIRVAAALQKTDKGEELDNLIRMNKSLNRNQGLDGLFRANLKAQQLDKRAQSLESLIYMNTQMDRDGKGNQAFGSFKKINQRADT-ERGSQDQRSIIRTNAMAERSSRR--------------------KQDLGGLINVNPETNKSMKRGQSLENLIKVTLEVNRSSKG--------------------GQSLDNFIKAVPATDRANQGSQGLDSLMKVTPSANKSNQHSLDELVNTSPKAVKTTAGHQDLDKFIKVNADVLTNNQRNHDLDNSIRGNPTVNRCDQSHDLDNLIKVKPSALRNTNGDQDLKGLTEVNSRVSEDKNERVDGQANGVTNSLRKESPRTSVYSHETKTSLSSNSGTRNAGPKDTVVYTRTYVENSKSPKDGYQENISGKYIQTVYSTSDRSVIERDMCTYCRKPLGVETKMILDELQICCHSTCFKCEICKRPLENLQAGDSIWIYRQTIHCEPCYSKVMAKWIQ", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9EQG3-1", "uniprot_id": "SCEL_MOUSE", "id": "Q9EQG3-1", "name": "Sciellin", "aln": "MSNFSSRKKSPTGNDLKS-ARGAELRQQGFQDVNKRRAFLQDNSWIKKPPEE----EQDGNYGRVVLNRHNSHDALDRKLIERDEPKATISRYRSEDMLD-----------------------RTLSSFRTPQSTKTPAVSSFNANTTATA---STPATTPVKKKRQSWFPPPPPGHNASPSTAASRRDPALHPPLPPKPCSPIASPKPLGRTNRQIHAATAGACG-ETERHAERNIRTEDLDDIIRVAAALQKTDKGEELDNLIRMNKSLNRNQGLDGLFRANLKAQQLDKRAQSLESLIYMNTQTDRDGKGNQAFGSLKKINQRADP-DRRSQDLRSVIRTHATAERIGRR--------------------KQDLDGLIKVNPDTNKNMKRGKSLDNLIKVTPEVNRSNKG--------------------GPSLDNFTKGVPARSRANQRDQDLDSLIKVTPSANRSSQHSLDELINTSPQTIKTTARHQDLDKFIKVNPDVLTNNQRNHDVDSTIRGNPTGTRCEQSEELDNLIKVKPSALRNTNGGQDLESLTEVNSHVAE-KNGRIDGQANGLTNSLFKESTRASVYSYEARNSLSSNSGNKNGGPKDTVVYTRTYVENSKSPKDGYQENISGKYIQTVYSTSDRSVIERDMCTYCRKPLGVETKMILDELQICCHSTCFKCEICKRPLENLQAGDSIWIYRQTIHCEPCYSKVMAKWIQ", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O95171-1", "uniprot_id": "SCEL_HUMAN", "id": "O95171-1", "name": "Sciellin", "aln": "MSNVTLRKMSPTGNEMKSTTQGTTRKQQDFHEVNKRRTFLQDNSWIKKRPEE----EKDENYGRVVLNRHNSHDALDRKVNERDVPKATISRYSSDDTLDRISDRNDAAKTYKANTLDNQLTNRSMSMFRSLEVTKLQPGGSLNANTSNTIA--STSATTPVKKKRQSWFPPPPPGYNASSSTGTRRREPGVHPPIPPKPSSPVSSPNQLRQDNRQIHPPKPGVYT-ETNRSAERNIRSQDLDNIVKVATSLQRSDKGEELDNLIKMNKSLNRNQGLDSLFRANPKVEEREKRAKSLESLIYMSTRTDKDGKGIQSLGSPIKVNQRTDKNEKGRQNLESVAKVNARMNKTSRRSEDLDNATEVNPKGHENTTGKKDLDGLIKVDPETNKNITRGQSLDNLIKVTPEVKRSNQGSKDLNNFIKVYPGTEKSTEGGQSLDSLIKVTPERNRTNQGNQDLENLIKVIPSANKSSEQGLDEHINVSPKAVKNTDGKQDLDKLIKVNPEIFTNNQRNQDLANLIKVNPAVIRNNQSQDLDNLIKVKPSALRNTNRDQNLENLIEVNSHVSENKNG-------------------------------SSNTGAKQAGPQDTVVYTRTYVENSKSPKDGYQENISGKYIQTVYSTSDRSVIERDMCTYCRKPLGVETKMILDELQICCHSTCFKCEICKQPLENLQAGDSIWIYRQTIHCEPCYSKIMAKWIP", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0ACD6B653-1", "uniprot_id": "A0ACD6B653_DANRE", "id": "A0ACD6B653-1", "name": "", "aln": "-MSFTGKSNSQSG------TTSSTGSINPVNESKKKTSLLKDNSWIKSNVNEDQKVEQETNFGKTVLSRYKSNESLTSPQDKTSKTETKTTTVTASPGSS---------------------VQALSKRFGGSQDKLNETRTPLNKPSVKSLPRTSTTSTTTTVKNGTKTTETTVTTTKQDVVKSSTKLETVIDRNPADSSTRRTGDYKTTRQEDITVKSSKDTVDGPSSPVKTTTSIKSYTKEDVLPAKTTPYSVQSTKSSENLTPTSSIMTTN--------TKPEISDSKTEVVTVKSSKTVIDTPASPVKTTTSIKTYTKEDVTSTNTKRPTSPVKTTTSIKTFTKEDVSP-------------------AKLTTTTTYTTKSDYKTEVATVKSSKDIIDIPASPVKTTTS-------------------IKTYTKEDVTSPKTTPYSVRSTKSSKDFLYDTPTKTSISDYKTEVVTVNSSKDIVDIPTSP-----VKTTTSYSIKSYTKEDVS-PTKTTSDSIRSTKSSEDLLYDTLIPLSIKSTNSKPDSSREDLSSSKTVR---------------------------------TVYSTIDRNEWSTDLSPSYTRTSYTESR-PFEYMSDSLTSKTTTTVYSSPERKVNAKDICTYCNQSMYTDEKFILDDMNINCHARCFKCGVCNTSLGNLRAGDSLWVYQCAIHCASCFGVTKNKWMR", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ..: :. * * : .: : .:: :*: ::*:******. :* *:: *:*:.**.*::*:::* : . .::. : :. . . * : . . .:. : . **.:**.. *: . .. . : ..: : :. :. . .. .. : : . :: .. . .: : .*:: :::: . :: :. :. :** .. :. * :: : .: .... :::* : * :: : * : : .: . .: :: :. * ....: :..: :* .::*.:. . ::. . .. . : : :. ..:: *: . .: : *.: : :*.... :. :.*: : .. * :* : .: * :::.** : . .*:. . *. . .: ... : **** :*: * : .:.::.* ****:.:*.* :*:****.:.: .: *:***:::* **: **** :*: .* **:****:*:*: :*** .*:. **: ", "identical_positions": 91, "similar_positions": 242, "identity": "12.53%" }, { "cls_id": "homologset.agr.MGI:1891236", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9WU11-1", "uniprot_id": "SNURF_RAT", "id": "Q9WU11-1", "name": "SNRPN upstream reading frame protein", "aln": "MERGRDRLHLRRTTEQHVPEIEVQVKRRRTASLSNQECHLYPRRSQQQQIPVVDFQAELRQAFLAETPRGG", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9WU12-1", "uniprot_id": "SNURF_MOUSE", "id": "Q9WU12-1", "name": "SNRPN upstream reading frame protein", "aln": "MERGRDRLHLRRTTEQHVPEVEVQVKRRRTASLSNQECHLYPRRSQQQQVPVVDFQAELRQAFLAETPRGG", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9Y675-1", "uniprot_id": "SNURF_HUMAN", "id": "Q9Y675-1", "name": "SNRPN upstream reading frame protein", "aln": "MERARDRLHLRRTTEQHVPEVEVQVKRRRTASLSNQECQLYPRRSQQQQVPVVDFQAELRQAFLAETPRGG", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F1LSU8-1", "uniprot_id": "F1LSU8_RAT", "id": "F1LSU8-1", "name": "", "aln": "MEERRGPLHLR-TTEQHVPEIEVQVKRRRTTSLCNQEYLLYPRCSQQQQVPVVDFQAEVRQAFSAETPRGG", "tax_id": 10116, "tax_name": "Rat" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "**. *. **** ********:*********:**.*** **** *****:********:**** *******", "identical_positions": 57, "similar_positions": 7, "identity": "80.28%" }, { "cls_id": "homologset.agr.MGI:1891247", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9ERC5-1", "uniprot_id": "OTOF_RAT", "id": "Q9ERC5-1", "name": "Otoferlin", "aln": "MALIVHLKTVSELRGRADRIAKVTFRGQSFYSRVLENCEDVADFDETFRWPVASSIDRNEVLEIQIFNYSKVFSNKLIGTFRMVLQKVVEENRVEVSDTLIDDNNAIIKTSLSMEVRYQAADGTVGPWDDGDFLGDESLQEEEKDSQETDGLLPGSRPSTRTPGEK----SFRSKGKEKTKGGRDGEHKAGRSVFSAMKLGKTRSHKEEPQRQDEPAVLEMEDLDHLAIRLGDGLDPDSVSLASVTALTSNVSNKRSKPDIKMEPSAGRPMDYQVSITVIEARQLVGLNMDPVVCVEVGDDKKYTSMKESTNCPYYNEYFVFDFHVSPDVMFDKIIKISVIHSKNLLRSGTLVGSFKMDVGTVYSQPEHQFHHKWAILSDPD------DISAGLKGYVKCDVAVVGKGDNIKTPHKANETDEDDIEGNLLLPEGVPPERQWARFYVKIYRAEGLPRMNTSLMANVKKAFIGENKDLVDPYVQVFFAGQKGKTSVQKSSYEPLWNEQVVFTDLFPPLCKRMKVQIRDSDKVNDVAIGTHFIDLRKISNDGDKGFLPTLGPAWVNMYGSTRNYTLLDEHQDLNEGLGEGVSFRARLMLGLAVEILDTSNP-ELTSSTEVQVEQATPVSESCTGRMEEFFLFGAFLEASMIDRKNGD--KPVTFEVTIGNYGNEVDGTSRPQRPRPRKE---PGDEEEVDLIQNSSDDEGDEAGDLASVSSTPPMRPQITDRNYFHLPYLERKPCIYIKSWWPDQRRRLYNANIMDHIADKLEEGLNDVQEMIKTEKSYPERRLRGVLEELSCGCHRFLSLSDKDQGHSSRTRLDRERLKSCMRELESMGQQAKSLRAQVKRHTVRDKLRLCQNFLQKLRFLADEPQHSIPDVFIWMMSNNKRIAYARVPSKDLLFS---IVEEELGKDCAKVKTLFLKLPGKRGFGSAGWTVQAKLELYLWLGLSKQRKDFLCGLPCGFEEVKAAQGLGLHSFPPISLVYTKKQTFQLRAHMYQARSLFAADSTGLSDPFARVFFINQSQCTEVLNETLCPTWDQMLVFDNLELYGEAHELRDDPPIIVIEIYDQDSMGKADFMGR----------------------TFAKPLVKMADEAYCPPRFPPQLEYYQIYRGNATAGDLLAAFELLQIGPSGKADLPPINGPVDMDRGPIMPVPVGIRPVLSKYRVEVLFWGLRDLKRVNLAQVDRPRVDIECAGKGVQSSLIHN-YKKNPNFNTLVKWFEVDLPENELLHPPLNIRVVDCRAFGRYTLVGSHAVSSLRRFIYRPPDRSAANWNT--------------------TGEVVVSMEPEVPVKKLETLVKLDATSDAVVKVDVAEDEKERKKKKKKGP-SEEAEEEEPDESMLDWWSKYFASIDTMKEQLRQHETSGIDLEEKEEMDSTEG---LKGPVKNKEKSRAAKEEKKKKNQNPGPGQGSEAPEKK-KAKIDELKVYPKELESEFDNFEDWLHTFNLLRGKTGDDE---DGSTEEERIVGRFKGSLCVYKVPLPEDVSREAGYDPTYG-------MFQGIPSNDPINVLVRIYVVRATDLHPADINGKADPYIAIKLGKTDIRDKENYISKQLNPVFGKSFDIEASFPMESMLTVAVYDWDLVGTDDLIGETKIDLENRFYSKHRATCGIAQTYSIHGYNIWRDPMKPSQILTRLCKEGKVDGPHFGPHGRVKVANRVFTGPSEIEDENGQRKPTDEHVALSALRHWEDIPRVGCRLVPEHVETRPLLNPDKPGIEQGRLELWVDMFPMDMPAPGTPLDISPRKPKKYELRVIVWNTDEVVLEDDDFFTGEKSSDIFVRGWLKGQQEDKQDTDVHYHSLTGEGNFNWRYLFPFDYLAAEEKIVMSKKESMFSWDETEYKIPARLTLQIWDADHFSADDFLGAIELDLNRFPRGAKTAKQCTMEMATGEVDVPLVSIFKQKRVKGWWPLLARNE----NDEFELTGKVEAELHLLTAEEAEKNPVGLARNEPDPLEKPNRPDTAFVWFLNPLKSIKYLICTRYKWLIIKIVLALLGLLMLALFLYSLPGYMVKKLLGA", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9ESF1-1", "uniprot_id": "OTOF_MOUSE", "id": "Q9ESF1-1", "name": "Otoferlin", "aln": "MALIVHLKTVSELRGKGDRIAKVTFRGQSFYSRVLENCEGVADFDETFRWPVASSIDRNEVLEIQIFNYSKVFSNKLIGTFCMVLQKVVEENRVEVTDTLMDDSNAIIKTSLSMEVRYQATDGTVGPWDDGDFLGDESLQEE-KDSQETDGLLPGSRPSTRISGEK----SFR---------------RAGRSVFSAMKLGKTRSHKEEPQRQDEPAVLEMEDLDHLAIQLGDGLDPDSVSLASVTALTSNVSNKRSKPDIKMEPSAGRPMDYQVSITVIEARQLVGLNMDPVVCVEVGDDKKYTSMKESTNCPYYNEYFVFDFHVSPDVMFDKIIKISVIHSKNLLRSGTLVGSFKMDVGTVYSQPEHQFHHKWAILSDPD------DISAGLKGYVKCDVAVVGKGDNIKTPHKANETDEDDIEGNLLLPEGVPPERQWARFYVKIYRAEGLPRMNTSLMANVKKAFIGENKDLVDPYVQVFFAGQKGKTSVQKSSYEPLWNEQVVFTDLFPPLCKRMKVQIRDSDKVNDVAIGTHFIDLRKISNDGDKGFLPTLGPAWVNMYGSTRNYTLLDEHQDLNEGLGEGVSFRARLMLGLAVEILDTSNP-ELTSSTEVQVEQATPVSESCTGRMEEFFLFGAFLEASMIDRKNGD--KPITFEVTIGNYGNEVDGMSRPLRPRPRKE---PGDEEEVDLIQNSSDDEGDEAGDLASVSSTPPMRPQITDRNYFHLPYLERKPCIYIKSWWPDQRRRLYNANIMDHIADKLEEGLNDVQEMIKTEKSYPERRLRGVLEELSCGCHRFLSLSDKDQGRSSRTRLDRERLKSCMRELESMGQQAKSLRAQVKRHTVRDKLRLCQNFLQKLRFLADEPQHSIPDVFIWMMSNNKRIAYARVPSKDLLFS---IVEEELGKDCAKVKTLFLKLPGKRGFGSAGWTVQAKLELYLWLGLSKQRKDFLCGLPCGFEEVKAAQGLGLHSFPPISLVYTKKQAFQLRAHMYQARSLFAADSSGLSDPFARVFFINQSQCTEVLNETLCPTWDQMLVFDNLELYGEAHELRDDPPIIVIEIYDQDSMGKADFMGR----------------------TFAKPLVKMADEAYCPPRFPPQLEYYQIYRGSATAGDLLAAFELLQIGPSGKADLPPINGPVDMDRGPIMPVPVGIRPVLSKYRVEVLFWGLRDLKRVNLAQVDRPRVDIECAGKGVQSSLIHN-YKKNPNFNTLVKWFEVDLPENELLHPPLNIRVVDCRAFGRYTLVGSHAVSSLRRFIYRPPDRSAPNWNTTVRLLRGCHRLRNGGPSSRPTGEVVVSMEPEEPVKKLETMVKLDATSDAVVKVDVAEDEKERKKKKKKGP-SEEPEEEEPDESMLDWWSKYFASIDTMKEQLRQHETSGTDLEEKEEMESAEG---LKGPMKSKEKSRAAKEEKKKKNQSPGPGQGSEAPEKK-KAKIDELKVYPKELESEFDSFEDWLHTFNLLRGKTGDDE---DGSTEEERIVGRFKGSLCVYKVPLPEDVSREAGYDPTYG-------MFQGIPSNDPINVLVRIYVVRATDLHPADINGKADPYIAIKLGKTDIRDKENYISKQLNPVFGKSFDIEASFPMESMLTVAVYDWDLVGTDDLIGETKIDLENRFYSKHRATCGIAQTYSIHGYNIWRDPMKPSQILTRLCKEGKVDGPHFGPHGRVRVANRVFTGPSEIEDENGQRKPTDEHVALSALRHWEDIPRVGCRLVPEHVETRPLLNPDKPGIEQGRLELWVDMFPMDMPAPGTPLDISPRKPKKYELRVIVWNTDEVVLEDDDFFTGEKSSDIFVRGWLKGQQEDKQDTDVHYHSLTGEGNFNWRYLFPFDYLAAEEKIVMSKKESMFSWDETEYKIPARLTLQIWDADHFSADDFLGAIELDLNRFPRGAKTAKQCTMEMATGEVDVPLVSIFKQKRVKGWWPLLARNE----NDEFELTGKVEAELHLLTAEEAEKNPVGLARNEPDPLEKPNRPDTSFIWFLNPLKSARYFLWHTYRWLLLKFLLLFLLLLLFALFLYSLPGYLAKKILGA", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9HC10-1", "uniprot_id": "OTOF_HUMAN", "id": "Q9HC10-1", "name": "Otoferlin", "aln": "MALLIHLKTVSELRGRGDRIAKVTFRGQSFYSRVLENCEDVADFDETFRWPVASSIDRNEMLEIQVFNYSKVFSNKLIGTFRMVLQKVVEESHVEVTDTLIDDNNAIIKTSLCVEVRYQATDGTVGSWDDGDFLGDESLQEEEKDSQETDGLLPGSRPSSRPPGEK----SFR---------------RAGRSVFSAMKLGKNRSHKEEPQRPDEPAVLEMEDLDHLAIRLGDGLDPDSVSLASVTALTTNVSNKRSKPDIKMEPSAGRPMDYQVSITVIEARQLVGLNMDPVVCVEVGDDKKYTSMKESTNCPYYNEYFVFDFHVSPDVMFDKIIKISVIHSKNLLRSGTLVGSFKMDVGTVYSQPEHQFHHKWAILSDPD------DISSGLKGYVKCDVAVVGKGDNIKTPHKANETDEDDIEGNLLLPEGVPPERQWARFYVKIYRAEGLPRMNTSLMANVKKAFIGENKDLVDPYVQVFFAGQKGKTSVQKSSYEPLWNEQVVFTDLFPPLCKRMKVQIRDSDKVNDVAIGTHFIDLRKISNDGDKGFLPTLGPAWVNMYGSTRNYTLLDEHQDLNEGLGEGVSFRARLLLGLAVEIVDTSNP-ELTSSTEVQVEQATPISESCAGKMEEFFLFGAFLEASMIDRRNGD--KPITFEVTIGNYGNEVDGLSRPQRPRPRKE---PGDEEEVDLIQNASDDEAGDAGDLASVSSTPPMRPQVTDRNYFHLPYLERKPCIYIKSWWPDQRRRLYNANIMDHIADKLEEGLNDIQEMIKTEKSYPERRLRGVLEELSCGCCRFLSLADKDQGHSSRTRLDRERLKSCMRELENMGQQARMLRAQVKRHTVRDKLRLCQNFLQKLRFLADEPQHSIPDIFIWMMSNNKRVAYARVPSKDLLFS---IVEEETGKDCAKVKTLFLKLPGKRGFGSAGWTVQAKVELYLWLGLSKQRKEFLCGLPCGFQEVKAAQGLGLHAFPPVSLVYTKKQAFQLRAHMYQARSLFAADSSGLSDPFARVFFINQSQCTEVLNETLCPTWDQMLVFDNLELYGEAHELRDDPPIIVIEIYDQDSMGKADFMGR----------------------TFAKPLVKMADEAYCPPRFPPQLEYYQIYRGNATAGDLLAAFELLQIGPAGKADLPPINGPVDVDRGPIMPVPMGIRPVLSKYRVEVLFWGLRDLKRVNLAQVDRPRVDIECAGKGVQSSLIHN-YKKNPNFNTLVKWFEVDLPENELLHPPLNIRVVDCRAFGRYTLVGSHAVSSLRRFIYRPPDRSAPSWNTTVRLLRRCRVLCNGGSSSHSTGEVVVTMEPEVPIKKLETMVKLDATSEAVVKVDVAEEEKE-KKKKKKGT-AEEPEEEEPDESMLDWWSKYFASIDTMKEQLRQQEPSGIDLEEKEEVDNTEG---LKGSMKGKEKARAAKEEKKKKTQSSGSGQGSEAPEKK-KPKIDELKVYPKELESEFDNFEDWLHTFNLLRGKTGDDE---DGSTEEERIVGRFKGSLCVYKVPLPEDVSREAGYDSTYG-------MFQGIPSNDPINVLVRVYVVRATDLHPADINGKADPYIAIRLGKTDIRDKENYISKQLNPVFGKSFDIEASFPMESMLTVAVYDWDLVGTDDLIGETKIDLENRFYSKHRATCGIAQTYSTHGYNIWRDPMKPSQILTRLCKDGKVDGPHFGPPGRVKVANRVFTGPSEIEDENGQRKPTDEHVALLALRHWEDIPRAGCRLVPEHVETRPLLNPDKPGIEQGRLELWVDMFPMDMPAPGTPLDISPRKPKKYELRVIIWNTDEVVLEDDDFFTGEKSSDIFVRGWLKGQQEDKQDTDVHYHSLTGEGNFNWRYLFPFDYLAAEEKIVISKKESMFSWDETEYKIPARLTLQIWDADHFSADDFLGAIELDLNRFPRGAKTAKQCTMEMATGEVDVPLVSIFKQKRVKGWWPLLARNE----NDEFELTGKVEAELHLLTAEEAEKNPVGLARNEPDPLEKPNRPDTSFIWFLNPLKSARYFLWHTYRWLLLKLLLLLLLLLLLALFLYSVPGYLVKKILGA", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q5SPC5-1", "uniprot_id": "OTOF_DANRE", "id": "Q5SPC5-1", "name": "Otoferlin", "aln": "MALVVHLKTVTELRGKGDRIAKVTFRGLSFFSRVLENCEDEARFEQAFRWPIGSQVDGDEMLEIQVFNYSKVFTNRLIGTFRMVLQKVVEEGHLEVSDTLIDDNNTAIQTTISIEIKYQTMDGSVKVWSDGEFL-DIPDDLDGTFQFETDSLLSGRSQSSGTSPGRSIHG-------------IPTFRKAGKGVFSAMKLGKTRTSKDDHKKGDDAAILDAEDLDRKAMRLGGILDPDTISLASVTAVTTNVSNKRSKPDIKMEPSSGRPVDYQISVTVIEARQLVGLNMDPVVCVEIGEEKKYTSMKESTNCPYYNEYFVFDFHVPPDVMFDKIIKISVIHSKNLLRSGTLVGTFKLDVGTVYTQPEHQFHHKWAMLSDPD------DITTGCKGYVKCDIAVVGKGDNIKTPHKASEADEDDIEGNLLLPEGVPSERQWARFYVKIYRAEGLPKMNTSIMANVKKAFIGENRDLVDPYVLVQFAGQKGKTSVQKSSYEPIWNEQVIFTEMFPPLCRRLKVQIRDSDKVNDVAIGTHFIDLRKVSNDGDKGFLPTMGPAWVNMYGSTRNYTLMDEHQDLNEGLGEGVSFRARLLISIAVEILDTTSA-EIMSSTEVHMEPVSNISESATGKMEEFFLFGSFLEATMIDRKIGD--KPISFEVTIGNYGNQIDGVSKPALAKKKKEGGGESEEEESELIHNSSEEEAEDDGDLTSVPSTPPMKPVITDRNYFHLPYFEKKPCIYIKSWWQDQRRRLYNSNIMDKIADKLEEGLNDVQEIIKTEKAYPERRLRGVLEELSTSCSRFVTLANKDQNLSGRTKLDRERLKSCMREMESMGQQAKTIRTQVKRNTVRDKLKLVLNFLQRLRFLADEPQHSIPDVFIWMISNNKRIAYARIPSKDILYS---IVDEEMGKDCGKVKAVFLRLPGKKGFGPAGWTVQAKLEMYLWLGLNKQRKDFLIGLPSGFEENKAVKGIGIQAVPPISLVYNMKQVFQLRAHMYQARSLFAADTSGLSDPFARVFFSTHSQVTEVLSETLCPTWDQLLVFDNVELYGEAGELRDDPPIIVIELYDQDTVGKAEFIGR----------------------TFAKPLTKMVDEHYGPPRFPPQLEYYQIYRGNCAAGDLLAAFELLQIGPAGRAALPPIDGPTDSDRGPILPVPLGIRPVLSRYRIEVLFWGLRDLKRVNLAQVDRPRVDIECAGKGVQSALIQN-YKKNPNFSTLVKWFEVDLPENELLHPPLNIRVVDCRAFGRYILVGSHAVTTLRKFIYSPPDKTANNWAH--------------------TGDIVVNMSPEPNIKKMDTVVKIEATTDAVVKVDLNEDEKEKEKKKKKKKKGEEVEEEEPDESMLDWWSKYFASIETMMENLRAQEAAQAEAEEREDLEIAAESAEIKADDFPMKGTKPKEKSKDKKSTKDKKKNNDGTEKRPPKPKVDELMVYNKELESEFGSFEDWLHTFNLYRGKAGDDD--DHNVVDEDRIVGRFKGSLCMYKLPLSEEITREAGFDPNMG-------MFQSIPHNDPINVLVRIYIIRATDLHPADINGKADPYIVIKLGKSDIRDKENYISKQLNPVFGKSFDIEATFPMESMLTVAVYDWDLVGTDDLIGETKIDLENRYYSKHRATCGIASNYSVHGYNVWRDPQKPAQILAKLCKEGKLDGPHYGPGGRVKVANRIFLGPTEIEDESGLKKQTEEHLALTVLRHWEEIPRVGCKLIPEHVETRPLLNPDKPGIEQGRIEMWVDMFPMDVPAPGPAIDISPRKPKRYELRVIIWNTDEVILEDDDYFTGEKSSDIFVRGWLKGQQEDKQDTDVHYHSLTGEGNFNWRFVFPFDYLMAEEKIVISKKESMFSWDETEYKIPARLTLQVWDADHFSADDFLGAIELDLNKFPRGAKTAKQCSLDMVLKEHELPTISIFKQKRVKGWWPFVAQNE----NDEFELTGKVEAELHLLTAEEAEKSPVGLGRNDPEPLEKPNRPDTSLMWFMNPLRSIRYFIWHNYRWLILKALALLLLLLLVGLFLYSIPGYLVKKLLGA", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8M9P0R6-1", "uniprot_id": "A0A8M9P0R6_DANRE", "id": "A0A8M9P0R6-1", "name": "Otoferlin", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MKRNKHRSSKDDGKGQDEPAILETEDMR--------MPDPDTISLASVTAVTTNVSNKRSKPDIKIEPSAGRPMDFQVSVTVIEARQLVGLNMDPVVCVEIGDDKKYTSMKESTNCPYYNEYFVFDFHVPPDVMFDKILKVSVIHSKNLLRSGTLVGSFKLDVGTIYTQPDHQFFHKWATLCDPE------DITAGLKGYVKCDIAVVAKGDTIKTPHKANENDEDDIESNLLLPEDVPAERQWARFYLKIYRAEGLPKMNTSIMANVKKAFIGENKDLVDPYVQVLFAGQKGKTSIQKSSYEPIWNEQIVFTEQFPPLCRRMKLQIRDSDKVNDVAIGTHFIDLRKIANDGDKGFLPTLGPAWVNMYGSTRSYTLMDEYQDLNEGLGEGVSFRARLLISLAVEILDTSSP-EVMSSTEVQVEGIPNISDNATGKVEEFFLFGSFLEATMIDRKIGD--KPINFEVTIGNYGSELDTPTKPKSKKKK----GDGDDEESELIHGSSDEEVDDGGDVTSVSTTPPMKPVITDRNYFHLPYFERKPCIYIYSWWQDQRRRLYNANVLDKMADKLEEGLNDVQEIIKTEKAYPERRLRGVLEELSNSCSTFVSLANNDQNQAGRTKLDKERVKLCMQEVESMGQQAKTMRSQVKKSNVKDRIKLAQNFLHKLRFLSDEPQHSVPDIYIWMISNNKRIAYARVPSKDILYS---SVEEECGKDCGKVQTIFFKLPGKKSFGPAGWTVQAKTELYLWLGLNRQRKDYLCGLPNGFEENKAVKGPGVQSSPPISLMYTMKQIFQLRVHMYQARSLFAADSTGLSDPFARIFFSTHSQVTEVLNETLCPTWDQLLVFDHVELYGEAGELRDDPPIIVIEIYDQDTVGKADFMGR----------------------TFAKPITKMSDEHYGPPRFPPQLEYYQIYRGNCTAGEMLAAFELLQIGPGGKADLPPIDGPTDIDRGPILPVPIGIRPVLSKYRIEVLFWGLRDLKRVNLAQVDRPRVDIECAGKGVQSSLIQN-YKKNPNFSTLVKWFEVDLPENELLHPPLNIRVVDCRAFGRYTLVGSHAVTTLRKFIYRPADKSVNNWSA--------------------MEEVVIHTEPEPAVKKIETVVKLDSASDAVVKVDMPDDEKG-GKGKKKRKKGEEVEEEELDESMLDWWSKYFASIETLKEAMKAQEA---EAEEKEDFESGDG--------------------KKKRGKKSKTIPGEAVPEKK-KQKIEEFKVYNRELEYEYNQFEDWLHTFNLHRGKCSDDADVDQNAADEDRLIGKFKGSLCIYKVS-SDDMSRDMGFDSNMG-------MFQNIPHNDPINVLVRIYVVRATDLHPADINGKADPYIAIKLGKSEIKDKENYISKQLNPVFGKSFDVEATLPMDSTLTVSIYDWDLVGTDDLIGETKIDLENRFYSKHRATCGISSTYAIHGYNVWRDPLKPSHILAKLCKDGKIDAPQYGPGGRVKVTNRVYTGPTEVEDENGLKKQTDEHLALAVLNHWEDIPRIGCKLVPEHMETRPLLNPDKPGIEQGRIEMWVDMFPKDMSAPGPALDISPRKPKKFELRVIVWNTDEVVLEDDDIFTGEKSSDIFVRGWLKGQQEDKQDTDVHYHSLTGEGNFNWRFIYPFDYLQAEEKIVISKKESMFSWDETEYKIPARLNLQVWDADHFSADDFLGAIELDLNRFPRGAKTAKQCSIEMVTNENEMPMVNIFKQKRIKGWWPFVARDE----NDELEITGKVEAELQLLTGEEAEKSPVGEGRNEPEPLEKPNRPDTAMLWFLMPLKAIRHLVCNQYKWLAIKLVLALMLLAILGLFLYSMPGYMVKKLLGA", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "B7Z0E5-1", "uniprot_id": "B7Z0E5_DROME", "id": "B7Z0E5-1", "name": "", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSYMDDCFAGAPQEFLICITVHKAAQVGVTTGELYVRISLDKMTKSTKSFPNTENPFFNEYFVFEFHCTLTELLRLTILFELKKHMTYKKN-VVVGELLVDLHSVWNQSNHGYFKKWGRLEAPIGENQTLENAVAPHGYLQLDLAIVSQHSPVSYALGSEEQDTQNLN-KWTVDHDFDDIEKNLLTNVNIFAPSNIR----YFVAFYRGYFIKQS----NYMIQVSFAGFNGKTPVVKNTTTPVWNYEINFAWMYPSVAQRFLILIFAHEHLQWKCVAEFELCLEEIAFNG----TPSLGPTYLHLYDPVN-----------------PMIYVGRLLMELRSEMLTDSQPTHTLSSKTVPGLDETRFWHDDVYLIEFLPLMGHHILTSGTAYKISARLAEHTSNVLEGQLRTPLDRFKSAMNSKNFRR---EAPFQSCMFRVRLPDNRAKYESDFFMLDIVNYMRSELDTFKLFQRKYP-----------LQDDEQAKCLKVIVNNILTRIKEGLDAHRFDHDVQPQRTTWDINRQLYLLDYFAKLPLELQN-----------LKQKLRSCFLEHLDTSIGDVVNELQRLVAEIGSLSSMAR------------TQDEWPELVLSLSASGKDVGVCRLNAKLFLNLRNQDADQDQETLCWRLKSFSFKSAGCSHTCPNCGCTTAIVSGCLSIVVERERKRFLAVVNKEWAN----------IEPMLWQLNPEQTHFLCHVYIHQAKVRPGGEKKNICDSHLRVLFADQACETYTSPGTLSPIWNAVITFNWVSLPGGIGLYLKNPPLLSLEFYNSERSLPEDLVGMGSVAMSVISEDRASDSNWEDAGVFGCSKNPLRKLQRLKYLTPPPLKWVPIARKGTLQAEVLMSAEIIQISMESLTTGQNDKKEPQLATG----IPMAIRPTMQNFVLEVFFVGLRNYSKSSMSSAGKRKINLMMGDLVLSSGPSTARIRNSINFLVAYASGVVSLPDQQDYWPAIIATDVLLSGFSSESILGAALIPNSSNFLQRD--------------------------------------------RTLKCVFKKEQEAAEASTTVSVDEDDEDEEEELEWE-----EEETKPSRISSWWMRLLFAFG-LRPAPYANRHALRFHDDLDDHELVEE------------------REFTWWTKFYNSMYWSAAEMCHEHKHRLVIYYEELEKQAQFGYLQDWAVPVQLVHGVKFKKHG---PPKEDIYATLKLQLKLTPCQCPVLEDPGGGGDMVRNMSNPIHPRHQSTLQSLGETVKLLVRVYVVQGVQMRPRDVKGDSDCYVKLFLGGKTFSDRAHFSPNHSNPVFGRLFEMEATLPGDHMLQVMVYDHDKI-KDEVIGQTNIDLEDRWRTRHRATVGLANEYTKSGYNHWHDVKLPSEILIDLCQKRGIQAPYYYG-NVIEVDGMLFGDETLISKD----EELQERLSLAVLKNMDKLPSFGYKLVPEHVETRSLCRDDFPNVEQGKLQLWIELFEANIYVP-SPIDITPVPPADFEVRVVVKNLVGIQAGDKNIFG-KLMSDVYVIGWCE-DEDKRQSTDIHYRSFAGDAAFNWRMVFGLKYSPNEDLMVIRRKAGLL--EEIEFKKPPIIYLQVWDKDVLTKDEYLAALELNLSNMYAPYPAAQLCKPYPKKRKR----INLFKRKVINGWFPLQSNAHPSQRSQAAVQNGKMQLSIEVCTDVEAVNRPAGRGQDPPMALEPPYRPDSSFNPLTHPCKSFQHILWPVIRKYVLWTLLILIVILGLVLFFSNLPAKLMTIPLE-", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . : :* * :: :.:** :* *: . : * :.:.. .* *. .*: *::******:** . :: : ..: : . :. .:** : :*: :::.*.:* :.:**. * * : : . :**:: *:*:*.: . :. . :.* * :::: : : ... .: ::*: ...: ::* : ** :. : : * *** :***.: *.: *:** :: *: :*.:.:*: : * :::: .:. . : *.::: :* *::**:::::*.... : : .**:: : *:: :.. . **. * . . .. . :* : *:* .: :: : . . :* *: . :* . . : . :. : .::. .*. : . *:. : : *: * *:.: ::::: :::***: : ..: . :. * *. . : * : ::::: *: * . . . * : . : .*.. *:: : : :..* :. .*: :* :* .::: . * ::::. :: .* . . * . * : :.::** :* : : : * : : : * :.:::**: ..:...:.*.. *::* :: * . **.* *: ::.*: :.* * .:**:: :*:*:.: :::* .*. . : . ** *:: * * . .::* : *::**. . : . : * :*:.***.:..: :**:* ***: .: .::...: :::: .. :.*. ::. ** . *.**::: *.: * .*. ::*: :.. .*: :.:. :.* : : . .. :::. : : : *** . : .** : : :: : :. :: :: : . . : : : * : ::. ::** ..:* :* .. :: ::: .* : . :: . . . . .:.:::***:*:::..:::* *::*.:* *: : ** . : *: :: .:: *****: *::**::* : * * :** * : .*::**:*:****:*: ::**** *::. *: *** *:* *:.** **:. ::.* : . :.* . :: . : :..: : :*:::* .*.: :.:* * :*:***:***.* . * *.:***::::*:::* :: .* ..:**:* * :*:**:: * : *.: * : **::* ** : :::.:*.**:**:*::*:. **** :: :.* *: :*: :* .:: :* *:* *. : **:** * :: *::*.*:**:*..: :*: *. : :.:**:* ::**:*: :. . .: .**:: .:.: * ** : *.* .:: * .** * ***::: : * :: :::: : : : :: : . **: .:*. : . * ", "identical_positions": 309, "similar_positions": 641, "identity": "14.9%" }, { "cls_id": "homologset.agr.MGI:1891250", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8BHL4-1", "uniprot_id": "RAI3_MOUSE", "id": "Q8BHL4-1", "name": "Retinoic acid-induced protein 3", "aln": "MTTP-TTAPSGCRSDLDSRYHRLCDLAEGWGIALETLAAVGAVATVACMFALVFLICKVQDSNKRKMLPAQFLFLLGVLGVFGLTFAFIIKLDGATGPTRFFLFGVLFAICFSCLLAHAFNLIKLVRGRKPLSWLVILSLAVGFSLVQDVIAIEYLVLTMNRTNVNVFSELPAPRRNEDFVMLLIYVLVLMVLTFFTSFLVFCGSFSGWKRHGFHICFTSFLSIAIWVAWIVLLLIPDIDRKWDDTILSTALVANGWVFLAFYILPEFRQLPRQRSPTDYPVEDAFCKPQLMKQSYGVENRAYSQEEITQGL-EMGDTLYAPYSTHFQLQNH--QKDFSIPRAQAPASPYNDYEGRKGDS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0ABK0LV83-1", "uniprot_id": "A0ABK0LV83_RAT", "id": "A0ABK0LV83-1", "name": "", "aln": "MTTPRAAAPSGCRSDLDSRYYRLCDLAEGWGIALETLAAVGAVATVALMFALVFLICKVQDSSKRKMLPTQFLFLLGVLGVFGLTFAFIIKLDRATGPTRFFLFGVLFALCFSCLLAHAFNLIKLVRGRKPLSWLVILSLAVGFSLVQDVIAIEFLVLTMNRTNVNVFSQLPAPRRNEDFVMLLIYVLFLMVLTFVASLLVFCGSFSGWKRHGIHICLTSFLSIAIWVAWIILLLIPDIDRKWDDTILSTVLVANGWVFLVFYILPEFRQLPRQRSSTDYPVEDAFCKPQLMKQSYGVENRAYSQEEITQGLEEMGDTLYAPYSTHFQMQNR--QKDFSIPRAHTPASPYNDYEGRKGDS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8NFJ5-1", "uniprot_id": "RAI3_HUMAN", "id": "Q8NFJ5-1", "name": "Retinoic acid-induced protein 3", "aln": "MATT---VPDGCRNGLKSKYYRLCDKAEAWGIVLETVATAGVVTSVAFMLTLPILVCKVQDSNRRKMLPTQFLFLLGVLGIFGLTFAFIIGLDGSTGPTRFFLFGILFSICFSCLLAHAVSLTKLVRGRKPLSLLVILGLAVGFSLVQDVIAIEYIVLTMNRTNVNVFSELSAPRRNEDFVLLLTYVLFLMALTFLMSSFTFCGSFTGWKRHGAHIYLTMLLSIAIWVAWITLLMLPDFDRRWDDTILSSALAANGWVFLLAYVSPEFWLLTKQRNPMDYPVEDAFCKPQLVKKSYGVENRAYSQEEITQGFEETGDTLYAPYSTHFQLQNQPPQKEFSIPRAHAWPSPYKDYEVKKEGS", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*:*. .*.***..*.*:*:**** **.***.***:*:.*.*::** *::* :*:******.:*****:**********:********* ** :**********:**::*********..* ********** ****.***************::*************:*.*********:** ***.**.***. * :.*****:****** ** :* :********** **::**:**:*******:.*.******* *: *** *.:**.. *************:*:*****************: * *************:**: **:******:: .***:*** :* .*", "identical_positions": 261, "similar_positions": 69, "identity": "72.5%" }, { "cls_id": "homologset.agr.MGI:1891254", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0ABK0LSR0-1", "uniprot_id": "A0ABK0LSR0_RAT", "id": "A0ABK0LSR0-1", "name": "BAG family molecular chaperone regulator 2", "aln": "MAQAKISAKAHEG---RFCRSSSMADRSSRLLESLDQLELSLNRVEALRDAATAVEQEKEILLEMIHSIQNSQDMRQISDGEREELNLTANRLMGRTLTVEVSVETIRNPQQEESLKHATKIIDEVVSKFLDDLGNAKSHLMSLYSACSSEVPPGPVDQKFQSIVIGCALEDQKKIKRRLETLLRNIDNSDKAIKLLEHTKGSGSKNLQN-TDNKFN", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q91YN9-1", "uniprot_id": "BAG2_MOUSE", "id": "Q91YN9-1", "name": "BAG family molecular chaperone regulator 2", "aln": "MAQAKISAKAHEG---RFCRSSSMADRSSRLLESLDQLEL---RVEALRDAATAVEQEKEILLEMIHSIQNSQDMRQISDGEREELNLTANRLMGRTLTVEVSVETIRNPQQEESLKHATRIIDEVVSKFLDDLGNAKSHLMSLYSACSSEVPPGPVDQKFQSIVIGCALEDQKKIKRRLETLLRNIDNSDKAIKLLEHAKGAGSKSLQN-TDGKFN", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O95816-1", "uniprot_id": "BAG2_HUMAN", "id": "O95816-1", "name": "BAG family molecular chaperone regulator 2", "aln": "MAQAKINAKANEG---RFCRSSSMADRSSRLLESLDQLEL---RVEALREAATAVEQEKEILLEMIHSIQNSQDMRQISDGEREELNLTANRLMGRTLTVEVSVETIRNPQQQESLKHATRIIDEVVNKFLDDLGNAKSHLMSLYSACSSEVPHGPVDQKFQSIVIGCALEDQKKIKRRLETLLRNIENSDKAIKLLEHSKGAGSKTLQQNAESRFN", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1PFF3-1", "uniprot_id": "A0A8M1PFF3_DANRE", "id": "A0A8M1PFF3-1", "name": "", "aln": "MAQAKINAKMNDATKNKFTRTMSMADRSGRLLESLDQIEM---RVEALREEASAMEQERECLIEMIQSIQNSQEMRSICDGEREELSLTAARLMGRTLTVKVSLETIRNQQQEEALQKAMKMIDEITEKVLEDLQSARTRLEALHAACVSDAPPVPVDQKFQSVVISCALEDQKKIKRRLETLIRNMDNAEKTIQIMDNPK----VDLSKLANGK--", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "******.** ::. :* *: ******.********:*: ******: *:*:***:* *:***:******:**.*.*******.*** *********:**:***** **:*:*::* ::***:..*.*:** .*:::* :*::** *:.* ********:**.****************:**::*::*:*:::::.* *.: ::.: ", "identical_positions": 128, "similar_positions": 61, "identity": "58.99%" }, { "cls_id": "homologset.agr.MGI:1891258", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q3ULW8-1", "uniprot_id": "PARP3_MOUSE", "id": "Q3ULW8-1", "name": "Protein mono-ADP-ribosyltransferase PARP3", "aln": "MAPKRKASVQTEGS--KKRRQGTEEEDSFRSTAEALRAAPADNRVIRVDPSCPFSRNPGIQVHEDYDCTLNQTNIGNNNNKFYIIQLLEEGSRFF-CWNRWGRVGEVGQSKMNHFTCLEDAKKDFKKKFWEKTKNKWEERDRFVAQPNKYTLIEVQGEAESQEAVVKALSPQVYSGPVRTVVK---PCSLDPATQNLITNIFSKEMFKNAMTLMNLDVKKMPLGKLTKQQIARGFEALEALEEAMKNPTGDGQSLEELSSCFYTVIPHNFGRSRPPPINSPDVLQAKKDMLLVLADIELAQTLQAAPGEEEEKVEEVPHPLDRDYQLLRCQLQLLDSGESEYKAIQTYLKQTGNSYRCPDLRHVWKVNREGEGDRFQAHSKLGNRRLLWHGTNVAVVAAILTSGLRIMPHSGGRVGKGIYFASENSKSAGYVTTMHCGGHQVGYMFLGEVALGKEHHITIDDPSLKSPPSGFDSVIARGQTEPDPAQDIELELDGQPVVVPQGPPVQCPSFKSSSFSQSEYLIYKESQCRLRYLLEIHL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8J8XBZ3-1", "uniprot_id": "A0A8J8XBZ3_RAT", "id": "A0A8J8XBZ3-1", "name": "Poly [ADP-ribose] polymerase", "aln": "MAPKRKSSMQTEGS--KKQRQGTGEEGSFRSTAEALRAAPAGNRIIRVDPPCPLSGNPGIQVHEDYDCTLNQTNIGNNNNKFYIIQLLEEGGRFS-CWNRWGRVGEVGQSKMNHFGCLEDAKKDFKKKFWEKTKNKWEERDHFVAHPNKYTLIEVQGEAETQEAVVKVD------GPVRTVFK---PCSLDPATQKLITNIFSKEMFKNAMTLMNLDVKKMPLGKLSKQQIARGFEALEALEEAMKNPTGDGQSLEELSSCFYTVIPHNFGRSRPPPINSPDILQAKKDMLLVLADIELAQTLQAAPGEEE-KVEEVPHPLDRDYQLLKCQLQLLDPGESEYKAIQTYLEQTGNGYRRPDLQHVWKVNREGEGDRFQAHSKLGNRRLLWHGTNVAVVAAILTSGLRIMPHSGGRVGKGIYFASENSKSASYVTAMRCGSHQVGYMFLGEVALGKVHHITMDDPSLKSPPPGFDSVIARGQTEPDPAQDIELQLDGQPVVVPQGRPVACPSFKSSSFSQS-GPAHDTPAAHPEACAHTS-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9Y6F1-1", "uniprot_id": "PARP3_HUMAN", "id": "Q9Y6F1-1", "name": "Protein mono-ADP-ribosyltransferase PARP3", "aln": "MAPKPKPWVQTEGPEKKKGRQAGREEDPFRSTAEALKAIPAEKRIIRVDPTCPLSSNPGTQVYEDYNCTLNQTNIENNNNKFYIIQLLQDSNRFFTCWNRWGRVGEVGQSKINHFTRLEDAKKDFEKKFREKTKNNWAERDHFVSHPGKYTLIEVQAEDEAQEAVVKVDR-----GPVRTVTKRVQPCSLDPATQKLITNIFSKEMFKNTMALMDLDVKKMPLGKLSKQQIARGFEALEALEEALKGPTDGGQSLEELSSHFYTVIPHNFGHSQPPPINSPELLQAKKDMLLVLADIELAQALQAVS-EQEKTVEEVPHPLDRDYQLLKCQLQLLDSGAPEYKVIQTYLEQTGSNHRCPTLQHIWKVNQEGEEDRFQAHSKLGNRKLLWHGTNMAVVAAILTSGLRIMPHSGGRVGKGIYFASENSKSAGYVIGMKCGAHHVGYMFLGEVALGREHHINTDNPSLKSPPPGFDSVIARGHTEPDPTQDTELELDGQQVVVPQGQPVPCPEFSSSTFSQSEYLIYQESQCRLRYLLEVHL", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "**** *. :****. ** **. **..********:* ** :*:*****.**:* *** **:***:******** ************::..** ***************:*** ********:*** *****:* ***:**::*.********.* *:******. ****** * *********:*************:*:**:***********:*****************:*.**..********* **********:*:*******::******************:***.. *:* .***************:*******.* .***.*****:***..:* * *:*:****:*** ************:*******:***********************************.** *:**.*:************: ***. *:*******.*********:*****:** **:**** ****** ** **.*.**:**** :. . .: . . ", "identical_positions": 402, "similar_positions": 79, "identity": "74.58%" }, { "cls_id": "homologset.agr.MGI:1891259", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9JI60-1", "uniprot_id": "LRAT_MOUSE", "id": "Q9JI60-1", "name": "Lecithin retinol acyltransferase", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MKNPMLEAASLLLEKLLLISNFKLFSVSVPGGGTGKNRPYEISSFVRGD------------VLEVSRTHFIHYG---IYLGENR----------VAHLMPDILLALTNDKERTQKVVSNKRLLLGVICKVASIRVDT-VEDFAYG----------------------ADILVNHLDGTLKKKSLLNEEVARRAEQQLG---------------LTPYSLLWNNCEHFVTYCRYGSRISPQ-----AEKFYDTVKIIIRDQRSSLASAVLG-------LASIVYTG----------------------LASYMTLPAICIPFCLWMMSG---------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9JI61-1", "uniprot_id": "LRAT_RAT", "id": "Q9JI61-1", "name": "Lecithin retinol acyltransferase", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MKNSMLEAASLLLEKLLLISNFKIFSVCAPGGGTGKKHPYEINSFLRGD------------VLEVSRTHFTHYG---IYLGDNR----------VAHLMPDILLALTSDKERTQKVVSNKRLLPGVICKVASIRVDT-VEDFAYG----------------------ADILVNHLDETLKKKSLLNEEVARRAEQQLG---------------LTPYSLLWNNCEHFVTYCRYGSPISPQ-----AEKFHETVKILIRDQRSCLASAVLG-------LVSIIYTG----------------------LASYMTLPAVCIPFCLWMMSG---------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O95237-1", "uniprot_id": "LRAT_HUMAN", "id": "O95237-1", "name": "Lecithin retinol acyltransferase", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MKNPMLEVVSLLLEKLLLISNFTLFSSGAAGEDKGRNSFYETSSFHRGD------------VLEVPRTHLTHYG---IYLGDNR----------VAHMMPDILLALTDDMGRTQKVVSNKRLILGVIVKVASIRVDT-VEDFAYG----------------------ANILVNHLDESLQKKALLNEEVARRAEKLLG---------------FTPYSLLWNNCEHFVTYCRYGTPISPQ-----SDKFCETVKIIIRDQRSVLASAVLG-------LASIVCTG----------------------LVSYTTLPAIFIPFFLWMAG----------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F1Q7T8-1", "uniprot_id": "F1Q7T8_DANRE", "id": "F1Q7T8-1", "name": "", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MLDSLTFLFEKFFLFSNFNLFKSIWQPE-KEECAVKCHPALRRGD------------LLEVQRTLFIHYG---IYLGENR----------VAHLMPDIMPLLTSNKQHIKPVVTNKRLILGCMYRLASIRVDS-VEDFAYG----------------------APILTNDMDKKMKCQVLANEEVARRAEKLVG---------------DIPYSLLWNNCEHFVTYCRYGTPVSEQ-----TDKFCNCLKSIIRDQRSVALTIGMG-------VMYILCFG----------------------LAPSTTLPTILIPFILWMAG----------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A0R4IX64-1", "uniprot_id": "A0A0R4IX64_DANRE", "id": "A0A0R4IX64-1", "name": "", "aln": "MANLTRVSGSLHRLTVKVCSTSPLPFCGYSVLYPHSLSNVKSATVRCFARDSRHRHNIRHYSSSAHKTVRIGCASGFWGDTATSVPQLIYGGKLDFLVFDYLSEITMSLLSAAKAKAPQMGYAPDFVLSLSPFINDISKRGIRVVSNAGGVNPLACGAALQEVIQKAGLDLKVAVVTGDDLMPQKDSLTELRMTDAERKKPLPKTVHSMNVYLGALPIKRCLDLGADIVVTGRCVDSAVVLGPLMHSFAWDGSNHDLLAAGSLAGHLIECGAQATGGIFTDWHTVPDWDNMGFPVVECSADGSFTLCKPPKTGGLVSFGTVAEQLVYEIGDPRHYLLPDVTCDFSNVTITEITDVDGGAVKVGGAKGSPPSGDYKVCATYMDGFRATAVCPVGGPRAVEKARRTAESIIKRTQRIFKQLGLEDYTEVNIQVLGAEDTYGPHAVNTGVREAVVWMAVHHKQKKALEFFSREVAPAGTGMAPGLTAIVGGRPRISPVLKPFFFLYPKSDLEVQIHVNGEHVETHREAVSEPSLGETHNSSLRSEESSLSSTDLPSGPHTFRLEELAYTRSGDKGDSANIGVIARHPQYFPYLKKFITAEVVEQYFQHLIRKDQTGQPSVIRYELPGIHGLNFILLNSLGGGGVASLRSDPQGKAYGQMLLDYKLQGLPDLKSLINQKRVED", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : . : ..*.: . ** . :* * : . . : :* : * * .: . : * . :* . : : * : :**:: * : . : : ..*** . *: :*: :.: * * :. : .: : : :*.:.* : : : : * * .: * : ", "identical_positions": 26, "similar_positions": 61, "identity": "3.83%" }, { "cls_id": "homologset.agr.MGI:1891291", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q3TBV4-1", "uniprot_id": "KCNK6_MOUSE", "id": "Q3TBV4-1", "name": "Potassium channel subfamily K member 6", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------MRRGALLASALAAYAGYLALGALLVARLERPHEARLRAELGT--------------------LREQLLQHSPCVAAHALDAFV-ERVLAAGRLGRAALANASGAANASDPAWDFASALFFASTLVTTVGYGYTTPLTDAGKAFSIVFALLGVPITMLLLTASAQRLS---------------------------LLLTHAPLSWLSLHWGWPPQRAARWHLVALLMVIVAIFFLVPAAVFAYLEEAWSFLDAFYFCFISLSTIGLGDYVPGEAPGQPYRALYKVLVTAYL-------------------------FLGLVAMVLVLQTFRRVSDLHGLTELILLPDPDPASLSQDEDDQVAVLDARTD---------LHQHLSAASHADYASIPR-----------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "G3V8R8-1", "uniprot_id": "KCNK6_RAT", "id": "G3V8R8-1", "name": "Potassium channel subfamily K member 6", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------MRRGALLASALVAYAGYLALGALLVARLERPHEARLRAELGT--------------------LREQLLRHSPCVAAHALDAFV-ERVLAAGRLGRAVLANASGPANASDPAWDFASALFFASTLVTTVGYGYTTPLTDAGKAFSIVFALLGVPITMLLLTASAQRLS---------------------------LLLTHAPLSWLSLRWGWHPQRAARWHLVALLMVIVAIFFLIPAAVFAYLEEAWSFLDAFYFCFISLSTIGLGDYVPGEAPGQPYRSLYKVLVTAYL-------------------------FLGLVAMVLVLQTFRRVSDLHGLTELILLPDPDPARLHQDEDDQVDILDARTD---------LHQHLSAASHANYASIPR-----------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9Y257-1", "uniprot_id": "KCNK6_HUMAN", "id": "Q9Y257-1", "name": "Potassium channel subfamily K member 6", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------MRRGALLAGALAAYAAYLVLGALLVARLEGPHEARLRAELET--------------------LRAQLLQRSPCVAAPALDAFV-ERVLAAGRLGRVVLANASGSANASDPAWDFASALFFASTLITTVGYGYTTPLTDAGKAFSIAFALLGVPTTMLLLTASAQRLS---------------------------LLLTHVPLSWLSMRWGWDPRRAACWHLVALLGVVVTVCFLVPAVIFAHLEEAWSFLDAFYFCFISLSTIGLGDYVPGEAPGQPYRALYKVLVTVYL-------------------------FLGLVAMVLVLQTFRHVSDLHGLTELILLPPPCPASFNADEDDRVDILGPQPE---------SHQQLSASSHTDYASIPR-----------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1N7B3-1", "uniprot_id": "A0A8M1N7B3_DANRE", "id": "A0A8M1N7B3-1", "name": "Potassium channel subfamily K member", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------MSTAFRSCFMLIGFILAYFTYLLLGALVFSAIERPIEESLKADLSS--------------------LKAEFLNLS-CVNSTALETFL-ERVLKANKYGVSVLENASLRTN-----WDLASSLFFANTMVTTVGYGHTTPLSDAGKAFSIVYALIGVPFTMLVLTACVQRLM---------------------------HPLTYRPISACQRRAGLQQRSASVVHFIVLLFLVVLCFFVVPSLVFSAIEETWSFLDAFYFCFISLCTIGLGDFVPAEKPGQSLRALYKISVMVYL-------------------------FVGLMVMFLVLRTFHKLADVYGWTAFFHLP-----SCEEDEEDKEPIIEAGPEDDSPEAEKASIKPLDPSSQVSYNSINR-----------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P40310-1", "uniprot_id": "TOK1_YEAST", "id": "P40310-1", "name": "Outward-rectifier potassium channel TOK1", "aln": "MTRFMNSFAKQTLGYGNMATVEQESSAQAVDSHSNNTPKQAKGVLAEELKDALRFRDERVSIINAEPSSTLFVFWFVVSCYFPVITACLGPVANTISIACVVEKWRSLKNNSVVTNPRSNDTDVLMNQVKTVFDPPGIFAVNIISLVLGFTSNIILMLHFSKKLTYLKSQLINITGWTIAGGMLLVDVIVCSLNDMPSIYSKTIGFWFACISSGLYLVCTIILTIHFIGYKLGKYPPTFNLLPNERSIMAYTVLLSLWLIWGAGMFSGLLHITYGNALYFCTVSLLTVGLGDILPKSVGAKIMVLIFSLSGVVLMGLIVFMTRSIIQKSSGPIFFFHRVEKGRSKSWKHYMDSSKNLSEREAFDLMKCIRQTASRKQHWFSLSVTIAIFMAFWLLGALVFKFAEN-WSYFNCIYFCFLCLLTIGYGDYAPRTGAGRAFFVIWALGAVPLMGAILSTVGDLLFDISTSLDIKIGESFNNKVKSIVFNGRQRALSFMVNTGEIFEESDTADGDLEENTTSSQSSQISEFNDNNSEENDSGVTSPPASLQESFSSLSKASSPEGILPLEYVSSAEYALQDSGTCNLRNLQELLKAVKKLHRICLADKDYTLSFSDWSYIHKLHLRNITDIEEYTRGPEFWISPDTPLKFPLNEPHFAFMMLFKNIEELVGNLVEDEELYKVISKRKFLGEHRKTL", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : * . : : *.::. : : : . * .:: . . ::: : ** : * . ..:*:*... : *** * * : ..* : : ::* ** *:: . : *: . : : :. ::: : :* *: **:::.:****:.* *** **:.* .*:. :: : . : * . : .:. : :: : . :: . : . . : .: : .: *: : ", "identical_positions": 37, "similar_positions": 95, "identity": "5.35%" }, { "cls_id": "homologset.agr.MGI:1891295", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A0G2K0E7-1", "uniprot_id": "A0A0G2K0E7_RAT", "id": "A0A0G2K0E7-1", "name": "Ubiquitin-protein ligase E3B", "aln": "--MFTVSQTSRAWFLDKARQAREERLEQKERERSAVLIQALVRSFLCRRRLHKDVRREIDEFFTADES---GSSKRSALCIFKIARKLLFICKTT----EDNERMEKLCRSILSSMDAENEPKVWYVSLALSKDLTLLWIKQIKSILWYCCELLGQLKPEILQDSRLITLYLTMLVTFTDTSTWKILR-GKGESLRPALNHICANIMGHLNQRGFYSVLQVLLTRGLARPRPCLSKSTLTAAFTLALRPVVAAQFSDSLMRPFIIHIMSVPALVAHLSTMAPERLGVLESHDMLRKFIVFLRDRDRCQDACESLEGCHTLCLMGNLLHLGSLNLKMLEEETDG-FVSLLTQMLCYCQKYVSQKKSNLTHWHPVLGWFSQSVDYGLNDSMYLITKQLQFLWGVPLIRIFFSDILSKKLLEPPEPVPAQPQPSSPQTVLPVKSLLKRAFQKSASVRNILKPVGG--------RRVDSTEVRKVCSICVLYQTSLTTLTQIRLQILTGLTYLDDLLPKLWAFICELGPHGGLKLFLECLNNDTGESKQLLAMLMLFCDCSRHLITILDDIEVYEEQISFKLEELVTISSFLNSFVFKMIWDGIVENAK-GETLELFQSVHGWLMVLYERDCRRRFAPEDHWLRKDLKPGVLFQELDKDRKRAQLILLHIPHVVPHKNRVLLFRNMVIKEKEKLGLVETS----------SASPHVTHITIRRSRMLEDGYEQLRQLPQHAMKGAIRVKFVSDLGVDEAGIDQDGVFKEFLEEIIKRVFDPALNLFKTTSGDERLYPSPTSYIHENYLQLFEFVGKMLGKAVYEGIVVDVPFASFFLSQMLGHHHSVFYSSVDELPSLDSEFYKNLTSIKRYDG-DVADLGLTLSYDEDVMGQLVCHELVPGGKTIPVTDENKISYIHLMAHFRMHTQIKNQTAALISGFRSIIKPEWIRMFSTPELQRLISGDNAEIDLEDLKKHTVYYGGFHGSHRVIVWLWDILASDFTPGERAMFLKFVTSCSRPPLLGFAYLKPPFSIRCVEVSDDQDTGDTLGSVLRGFFTIRKREPGGRLPTSSTCFNLLKLPNYSKKSVLREKLRYAISMNTGFELS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9ES34-1", "uniprot_id": "UBE3B_MOUSE", "id": "Q9ES34-1", "name": "Ubiquitin-protein ligase E3B", "aln": "--MFTVSQTSRAWFIDRARQAREERLVQKERERSAVTIQALVRSFLCRRRLHRDIRKEIDEFFSADES---GSSKRSALCIFKIARRLLFICKTT----EDSERLEKLCRSILNSMDAENEPKVWYVSLALSKDLTLLWIKQIKSILWHCCELLGQLKPEILQDSRLITLYLTMLVTFTDTSTWKILR-GKGESLRPALNHICANIMGHLNQRGLYSVLQVLLTRGLARPRPCLSKGMLTAAFSLALRPVVAAQFSDNLMRPFIIHVMSVPALVAHLSTVAPERLGVLESHDMLRKFIVFLRDRDRCRDACESLEGCHTLCLMGNLLHLGSLSLRLLEEEMDG-FVSALTQMLCYCQKYVAQKKSNLTHWHPVLGWFSQPVDYGLNDSMYLITKQLQFLWAVPLIRILFSDILSRKLLEHAEPAPVQPQPSSPQTVLPVKSLLKRAFQKSASVRNILRPVGG--------RRVDSAEVRKVCNICVLYQTSLTTLTQIRLQILTGLTYLDDLLPKLWAFICELGPHGGLKLFLECLNNDTGESKQLLAMLMLFCDCSRHLITILDDIEVYEEQISFKLEELVTISSFLNSFVFKMIWDGIVENAK-GETLELFQSVHGWLMVLYERDCRRRFAPEDHWLRRDLKPGVLFQELDKDRRRAQLVLQHIPHVVPHKNRVLLFRNMVIKEKEKLGLVETS----------SASPHVTHITIRRSRMLEDGYEQLRQLSQHAMKGVIRVKFVNDLGVDEAGIDQDGVFKEFLEEIIKRVFDPALNLFKTTSGDERLYPSPTSYIHENYLQLFEFVGKMLGKAVYEGIVVDVPFASFFLSQMLGHHHSVFYSSVDELPSLDSEFYKNLTSIKRYDG-DIADLGLTLSYDEDVMGQLVCHELVPGGKTIPVTDENKISYIHLMAHFRMHTQIKNQTAALISGFRSIIKPEWIRMFSTPELQRLISGDNAEIDLEDLKKHTVYYGGFHGSHRVIIWLWDILASDFTPEERAMFLKFVTSCSRPPLLGFAYLKPPFSIRCVEVSDDQDTGDTLGSVLRGFFTIRKREPGGRLPTSSTCFNLLKLPNYSKKSVLREKLRYAISMNTGFELS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q7Z3V4-1", "uniprot_id": "UBE3B_HUMAN", "id": "Q7Z3V4-1", "name": "Ubiquitin-protein ligase E3B", "aln": "--MFTLSQTSRAWFIDRARQAREERLVQKERERAAVVIQAHVRSFLCRSRLQRDIRREIDDFFKADDP---ESTKRSALCIFKIARKLLFLFRIK----EDNERFEKLCRSILSSMDAENEPKVWYVSLACSKDLTLLWIQQIKNILWYCCDFLKQLKPEILQDSRLITLYLTMLVTFTDTSTWKILR-GKGESLRPAMNHICANIMGHLNQHGFYSVLQILLTRGLARPRPCLSKGTLTAAFSLALRPVIAAQFSDNLIRPFLIHIMSVPALVTHLSTVTPERLTVLESHDMLRKFIIFLRDQDRCRDVCESLEGCHTLCLMGNLLHLGSLSPRVLEEETDG-FVSLLTQTLCYCRKYVSQKKSNLTHWHPVLGWFSQSVDYGLNESMHLITKQLQFLWGVPLIRIFFCDILSKKLLESQE--PAHAQPASPQNVLPVKSLLKRAFQKSASVRNILRPVGG--------KRVDSAEVQKVCNICVLYQTSLTTLTQIRLQILTGLTYLDDLLPKLWAFICELGPHGGLKLFLECLNNDTEESKQLLAMLMLFCDCSRHLITILDDIEVYEEQISFKLEELVTISSFLNSFVFKMIWDGIVENAK-GETLELFQSVHGWLMVLYERDCRRRFTPEDHWLRKDLKPSVLFQELDRDRKRAQLILQYIPHVIPHKNRVLLFRTMVTKEKEKLGLVETS----------SASPHVTHITIRRSRMLEDGYEQLRQLSQHAMKGVIRVKFVNDLGVDEAGIDQDGVFKEFLEEIIKRVFDPALNLFKTTSGDERLYPSPTSYIHENYLQLFEFVGKMLGKAVYEGIVVDVPFASFFLSQLLGHHHSVFYSSVDELPSLDSEFYKNLTSIKRYDG-DITDLGLTLSYDEDVMGQLVCHELIPGGKTIPVTNENKISYIHLMAHFRMHTQIKNQTAALISGFRSIIKPEWIRMFSTPELQRLISGDNAEIDLEDLKKHTVYYGGFHGSHRVIIWLWDILASDFTPDERAMFLKFVTSCSRPPLLGFAYLKPPFSIRCVEVSDDQDTGDTLGSVLRGFFTIRKREPGGRLPTSSTCFNLLKLPNYSKKSVLREKLRYAISMNTGFELS", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8N1YZY7-1", "uniprot_id": "A0A8N1YZY7_DANRE", "id": "A0A8N1YZY7-1", "name": "Ubiquitin-protein ligase E3B", "aln": "--MFTATQTSKTQFLDKARVAREERKGHKEKERAATQIQALVRRFLCRCRLQKEIRKEVDDFIAVSDA---GPTKRNALSIFKIARKLLFILSK-----DDKLRFEKLCRIILNSMDVENEPKVWYVSLALSKDLTILWLKQIKDVLWVSCEFLKKLKPDILQDNKLVTLYLTMLITFTDTSTWKIIR-GKGEALKPALNRICENIMGHLNQKGFYSVLQILLTNGLARSRPSLSKGTLTAIFTLSLRPVIAAHFSDNLLRSFLLHVMSVPAFISHLNTLTPDCMITIQTHDLFRKFVLFLSREEQCLDICVCLEGSHTLCLLGNLIQLGYFNVKVLEQEAGH-FVKDLTDMLSYCQRYVSQKKSNLTHWHPVLGWFSQTVDYGLNESMPLVTKQLQCLWGVPVICTLFCDVLSKKLETQDPTPPPAPQPSSLQNNLPVKNLFKRAFQKSASVRNILKPVGG--------KRVDSAEVQKVCSICVLYQTALTTLTQIRLQILTGLTYLDELLPKLWAFICELGPQGGLRLFLECLNNDTEESKQLLAMLMLFCDCSRHLITILDDIEVYEEQISFKMEELVTISSFLNTFVYKMVWDGILENAK-GEKLDLFHSVHGWLMVLYERDCRRRFTPEDHWLRKDLKPSLLFQELEKGKKRAQLLLQYIPHVIPHKNRVLLFRNIVTKEKETLGLVETS----------SASPHVTHITIRRSRMLEDGYDQLRRLPVNSIKGVIRVKFVNDLGVDEAGIDQDGVFKEFLEEIIKKVFNPALNLFKTTSGNERLYPSPTSSIHENHLQLFEFVGKMLGKAMYEGIVVDVPFASFFLSQVLGHHHSTFYSSIDELPSLDSEFYKNLTSIKRYDG-DVSDLGLTLSYDEEVMGQLVCHELIPGGKTMPVTNENKISYIHLMAHFRMHTQIKEQTAAFIRGFRSIINPEWLHMFSTPEVQRLISGDNAEIDLDDLKKHTVYYGGFHSSHRVILWLWDILSSDFTPDERAMFLKFVTSCSRPPLLGFAYLKPPFSIRCVEVSDDQDTGDTLGSVLRGFFTIRKKEPGGRLPTSSTCFNLLKLPNYSKKSILRDKLRYAISMNTGFELS", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VSS9-1", "uniprot_id": "Q9VSS9_DROME", "id": "Q9VSS9-1", "name": "Ubiquitin-protein ligase E3B", "aln": "--MFAQNQ--KASFLEQTKAAREERALEKRREQAAILLQSTLKGYAARRKYQKRIILDFDAMFTENHDDKDAELELVASNVYPVLRRYLTQIRLDKSDVRARERLERICRYIIKAMESEN-TKLSYAALCLFKERSLPWIAHIKILLTNCLTLLPELKPENHADSLSLALFLHTLVVFTAPKSWAILRNAQFEKLQPAMQKICCNIQGHLVQHDFYKIMRLVLIRGTVREELSVKPVTLVAIITLCLRPLIDGNFSRNLLAKFLSEILSVPALIYHLQQSVPQCLEQFSSMGLLKKALSISGDVQWFEEFGTSMPGTKSLAFLGNIVNLFNIDGQGESKELAYPLLTETTTSLLELIPNTVTTKGVFTQWHELLGWHTPGPEPAQNQNVALIKKQFHMLWDHRCIKLLLGDLLKQINLNYERIEFQSPQQPS------ISNLLRRALERSSTRGVNLMGVASSKQSKQQWRKLDSAEVVQVSRICGMYYAALNTLSQMKLDILTGICYSDNVLYDIWLLITSLGPNCGMKEYLELLKSETNLQKPQTAMLMLFCDCMTHYVTILDEHEMYTEQNPFKLNDYVLLTYFLNNILYKLINDNLLAGAKNIVQHPVFLSLHTLMLCLYRRDCRRPFTPPKHWLIPEVKPSTFINDLEKAKRNAMLLLAKMPHIIPHEDRVKLFRKFVQNEKAVMGLTESA----------CASPRSALIVIHRDRIVEDGYRQLAAQPTQALKGVIRVRFINQQGLHEAGIDQDGVFKEFLEETIKKVFDPSLNLFKTTS-DQRLYPSPISYVQDNHLELFEFVGRMLGKAVYEGIVVDVPFASFFLSQLLGQTQQALYSCMDELPSLDNELYRSLTFIKHYKQ-DVSDLNLTFSVDQDVMGKIVTLALHPGGKARVVNDHNKLVYIHYMAFFHMNTQIREQTIAFNRGFRSIVNPEWLSLFSPPELQRLISGDTSPLDLKDLQKHTHYYGGFHDTHQVVCWLWDILAKDFTEEERKLFLKFVTSCSKPPLLGFAHLEPPFSIRCVEVSDDEDTGDTIGSVIRGFFAIRKKDPLNRLPTSSTCFNLLKLPNYQKKSTLRDKLRYAVSSNTGFELS", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P53119-1", "uniprot_id": "HUL5_YEAST", "id": "P53119-1", "name": "E3 ubiquitin-protein ligase HUL5", "aln": "MLNFTGQTRRRNVNLGNRTRNSKKDLLEKAKRERERRAQDKLKEDAS-KTIQKSIRRHFSNVRLFKNT---FTSSQLVHMIPAYGGKLIYYISQY-----DLQQLLKLSHNFLSSYPNSLGNRQLLSLLKLYQDD----------------ALVAETLSDLNMDCPTVDEFLDSLSVYLCRASFLSYS---------SASKLADVIEAWEVMHSSASISIFSISIGSYEK-----------------RPFALQFYCILAERNLLPQLINTNPILWDNMAKTYSHCSKGGQKNIAKLLIPNFNN---------------------------HIAPSVLRSDNDYVLKFYEKAFIDEVIATTANYVSDEDHVKNLMCYIASSPNQSCKN--------------SVLITLLSNKDFVRRLS---------------------WEFFHTKFNASKTEAHPLFSVLA---------QLIDMHLLISTDRELLDYNSVIPIEELKKFTST----LKDFTFRQYWELPKSERNPMLKEAVPLLSKVYER------------DSRLHFLSTENNPTYWENSE----KQFLNLRFYEELQEYEDLYREHLEEES-DEDMEKEIDLD--------KERPPLKSLLLNKMKKRLKSSLRFRKLE--------ILLELPFFIPFEERVDLFYMFIALDKKRLSLDDDHNLINMFTPWASTGMRKQSAIISRDNVLEDAFNAFNSIG-ERFKASLDVTFINEFG-EEAGIDGGGITKEFLTTVSDEGFKDPKHELFRTNDRYELYPS--VVYDATKLKYIWFLGKVVGKCLYEHVLIDVSFADFFLKKLLNYSN-GFLSSFSDLGSYDSVLYNNLIKLLNMTTDEIKSLDLTFEIDEPES-SAKVVDLIPNGSKTYVTKDNVLLYVTKVTDYKLNKRCFKPVSAFHGGLSVIIAPHWMEMFNSIELQMLISGERDNIDLDDLKSN-TEYGGYKEEDQTIVDFWEVLN-EFKFEEKLNFLKFVTSVPQAPLQGFKALDPKFGIRNAGTEK------------------------YRLPTASTCVNLLKLPDYRNKTILREKLLYAINSGARFDLS", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *: : : . :: .* :.. * :: . :: : ... . .. . . : : : :: ::.: ::.: . : * :: :: : .: * : :* * .: :: : .::. * . :. .: . : * . **. :. :: .::.. .:: . . . .: : : : .: : . : . . : : :: : : : . :: * : . : : .::: :: * : * * . :: . .: : :: .: ::: * .:. : : . : :: : *.. *. * :: :: : :. :: : : : : :: : : . .:. :: : : : :*.. :..*: :* :*..:*.::** ** :: :* :.* : .:. : * *..::**.: : . :*. : * *:.: * .***** .*: **** .. *. . : : *. .**** . . *: : *:*:::**.:** :::**.**.***.::*. : : *...:* * *. :*..* : . :: .*.**:. *: . * *.*. *...* : *: :: ::::.: : . *: *: *: *.*: :*.. *:* ****: :**.**:.: ***:: .:.: :*::* :*. *: ******* .:.** ** *.* *.** . ... ****:***.******:* :*: **:** **:. .: *:**", "identical_positions": 148, "similar_positions": 320, "identity": "13.44%" }, { "cls_id": "homologset.agr.MGI:1891304", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q7TN05-1", "uniprot_id": "AP1S3_MOUSE", "id": "Q7TN05-1", "name": "AP-1 complex subunit sigma-3", "aln": "---------------------------------------------------------MIHFILLFSRQGKLRLQKWYTTLPDKERKKITRDIIQTVLSRGHRTSSFIDWKELKLVYKRYASLYFCCAIE-NQDNELLTLEIVHRYVELLDKYFGNVCELDIIFNFEKAYFILDEFIIG-GEIQETSKKTAVKAIEDSDMLQETMEEYMNKPTF", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0ABK0L464-1", "uniprot_id": "A0ABK0L464_RAT", "id": "A0ABK0L464-1", "name": "", "aln": "MATGNLEVAGFQISRTDTALQPLRLPLGSVQHLSFPSVLWLLFGRLITSPGGSLPGFRIHFILLFSRQGKLRLQKWYTTLPDKERKKITREIIQTVLSRGHRTSSFIDWKELKLVYKRYASLYFCCAIE-NQDNELLTLEIVHRYVELLDKYFGNVCELDIIFNFEKAYFILDEFIIG-GEIQETSKKTAVKAIEDSDMLQETMEEYMNKPTF", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q96PC3-1", "uniprot_id": "AP1S3_HUMAN", "id": "Q96PC3-1", "name": "AP-1 complex subunit sigma-3", "aln": "---------------------------------------------------------MIHFILLFSRQGKLRLQKWYITLPDKERKKITREIVQIILSRGHRTSSFVDWKELKLVYKRYASLYFCCAIE-NQDNELLTLEIVHRYVELLDKYFGNVCELDIIFNFEKAYFILDEFIIG-GEIQETSKKIAVKAIEDSDMLQEVSTVSQTMGER", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M3AT20-1", "uniprot_id": "A0A8M3AT20_DANRE", "id": "A0A8M3AT20-1", "name": "AP complex subunit sigma", "aln": "------------------------------------------------MWTVPPSGKQMRFLLLFSRQGKLRLQKWFTVLSDRDKRKIIRDLTQMVLSRPPKACNFLPWRDLKIVYRRYASLYFCCGLE-QDDNELLTLDILHRYVELLDQYFGNVCELDIIFNFEKAYFILDEFVIG-GEVQETSKASVAKSIEEAESLQETMEEYLSKPTY", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P35181-1", "uniprot_id": "AP1S1_YEAST", "id": "P35181-1", "name": "AP-1 complex subunit sigma-1", "aln": "-------------------------------------------------------MTQLKYLLLVSRQGKIRLKKWYTAMSAGEKAKIVKDLTPTILARKPKMCNIIEYNDHKVVYKRYASLYFIVGMTPDVDNELLTLEIIHRFVETMDTYFGNVCELDIIFNFSKVYDILNEMIMCDGSIAESSRKEVLHHVTVMDTMESNDNLERVLS--", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ::::**.*****:**:**: .:. :: ** ::: :*:* : ..:: :.: *:**:******* .: : *******:*:**:** :* **************.*.* **:*::: *.: *:*: . : : : ::. ", "identical_positions": 60, "similar_positions": 52, "identity": "28.17%" }, { "cls_id": "homologset.agr.MGI:1891307", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D4A8C6-1", "uniprot_id": "D4A8C6_RAT", "id": "D4A8C6-1", "name": "", "aln": "---MSEPHRVQFTSLPG-----SLNPALLKKSRKEEVGGTEQHQDCEPAAAAVRITLTLFEPDHKRCPEFFYPELVKNTRGKVKGLHPGDKKK--DVLDPFNDEEKERHKVEALARKFEEKYG---GKKRRKDRIQDLIDMGYGYDESDSFIDNSEAYDELVPASLTTKYGGFYINSGTLQFRQASESEDDFIKEKKKKSPKKRKLKEGGEKIKKKKKDDTYDKEKKSKKSKFSKAGFTALNASKEKKKKKYSGSLSVREMLKKFQKEKEAQKKREEEHKPVAVSSVEAQGLRELEGTSDPLLSLFGSTSDNDLLQAATAMDSLTDLDLEQLLSESPEGSPFRDMDDGSDSLGVGLDQEFRQPSSFPEGLPTPLEKRVKELAQAARAAEGDSKQKFFTQDINGILLDIEVQTRELTSQIRSGVFAYLASFLPCSKDALVKRARKLHLYEQGGRLKEPLQKLKDAIGRAMPEQVAKYQDECQAHTQAKVAKMLEEEKDKEQRERICSDEEEDEEKGGRRIMGPRKKFQWNDEIRELLCQVVKIKLESRDLERNSKAQAWEDCVKAFLDAEVKPLWPKGWMQARTLFKESRRGHGHLTSLLAKKKVIAPSKVKTKESSVKPDKKVSIPSGQHGGPTTLLSEHQGGGLNIGANSREHPSQATCGLTDPVPVTLEDSLDEDLVRNPASSVDAVSKELAVLNSRAANSSEFTLPAPSKAPTEKVAGVLCTEEKRNFTKPSSSAPPPTNALQSPLNFLAEQALALGQSSQEKKPEG-SGYKELSCQAPLSKGMPELHQSKAKHHSLQRTSHGPQAAAPVPGPQVKVFHAGTQQQKSFTPPSPFVNKLQGPKATSPQCHRSFLQLVKTAAKGQSFHATMPASSGSSPASSSSSHKTTASNSTTISHPAKLHPASSVGPSYKNNPFAGSISKHGAASSSTSSGGGAQVQSSVSGTLLPGVQPPSAGQPASRTAPSSAVKKTPVTQKLTLVAPPGGPNGDSGGGTQGVAKLLTS-SLKPAAVSSVTSSTSLPKGTGGAVLLSNNSSLSLLSSSYKSNTPKLPGTMNSNSLGIIT--PFPLHVLSFSADSSAKAGVSKDAIVTGPAPGTFHHGLSHSLLAGLHSSPPHTAPLPHAAVSTHVPQSLPDTSQLHGKGPVVPRKL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q4G0F8-1", "uniprot_id": "UBN1_MOUSE", "id": "Q4G0F8-1", "name": "Ubinuclein-1", "aln": "---MSEPHRVQFTSVPG-----SLNPAFLKKSRKEEVGGTEQHQDCEPAAAAVRITLTLFEPDHKRCPEFFYPELVKNIRGKVKGLHPGDKKK--DVLDPFNDEEKERHKVEALARKFEEKYG---GKKRRKDRIQDLIDMGYGYDESDSFIDNSEAYDELVPASLTTKYGGFYINSGTLQFRQASESEDDFIKEKKKKSPKKRKLKEGGEKIKKKKKDDTYDKEKKSKKSKFSKAGFTALNASKEKKKKKYSGSLSVREMLKKFQKEKEAQKKREEEHKPVAVSSIEAQGLRELEGTSDPLLSLFGSTSDNDLLQAATAMDSLTDLDLEQLLSESPEGSPFRDMDDGSDSLGVGLDQEFRQPSSFPEGLPIPLEKRVKELAQAARAAEGESKQKFFTQDINGILLDIEVQTRELTSQIRSGVFAYLASFLPCSKDALVKRARKLHLYEQGGRLKEPLQKLKDAIGRAMPEQVAKYQDECQAHTQAKVAKMLEEEKDKEQRERICSDEEEDEEKGGRRIMGPRKKFQWNDEIRELLCQVVKIKLESRDLERNSKAQAWEDCVKAFLDAEVKPLWPKGWMQARTLFKESRRGHGHLTSLLAKKKVIAPSKIKMKESSVKLDKKVSVPSGQHGGPTTLLSEHQGGGLNTGANSREHPSQATCGLTDSVSVTLEDSLDEDLVRNPASSVDAVSKELATLNSRAANSSEFTLPTPSKAPTEKVGGVLCTEEKRNFAKPSSSAPPPTNALQSPLNFLAEQALALGQSSQEKKPEG-SGFKELSCQGPLSKGVPELHPSKAKHHNLPRTSHGPQAAAPVPGPQVKVFHAGTQQQKSFTPPSPFVNKLQGPKATSPQCHRSLLQLVKTAAKGQAFHATMPASSGSSPASSSSAHKTTASNSTTISHPAKLHPTSSVGPSYKNNPFAGSVSKHGASSSSPSPGGGAQVQSSVSGASLPGVQSPSAGQSASRAAPSSAVKKTPVTQKLTLVAPPGGPNGDSGGGTQGVAKLLTS-SLKPAAVSSVTSSTSLPKGTGGAVLLSNTSSLSLLSSSYKSNNPKLPGAMNSNSLGIIT--QFPLHVLSFNADSSAKAGVSKDAIVTGPAPGTFHHGLSHSLLAGLHSSPPHTAPLPHAAVSTHVPQSLPDASQLHGKGPVVPRKL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9NPG3-1", "uniprot_id": "UBN1_HUMAN", "id": "Q9NPG3-1", "name": "Ubinuclein-1", "aln": "---MSEPHRVQFTSLPG-----SLNPAFLKKSRKEEAGAGEQHQDCEPAAAAVRITLTLFEPDHKRCPEFFYPELVKNIRGKVKGLQPGDKKK--DLSDPFNDEEKERHKVEALARKFEEKYG---GKKRRKDRIQDLIDMGYGYDESDSFIDNSEAYDELVPASLTTKYGGFYINSGTLQFRQASESEDDFIKEKKKKSPKKRKLKEGGEKIKKKKKDDTYDKEKKSKKSKFSKAGFTALNASKEKKKKKYSGALSVKEMLKKFQKEKEAQKKREEEHKPVAVPSAEAQGLRELEGASDPLLSLFGSTSDNDLLQAATAMDSLTDLDLEHLLSESPEGSPFRDMDDGSDSLGVGLDQEFRQPSSLPEGLPAPLEKRVKELAQAARAAEGESRQKFFTQDINGILLDIEAQTRELSSQVRSGVYAYLASFLPCSKDALLKRARKLHLYEQGGRLKEPLQKLKEAIGRAMPEQMAKYQDECQAHTQAKVAKMLEEEKDKEQRDRICSDEEEDEEKGGRRIMGPRKKFQWNDEIRELLCQVVKIKLESQDLERNNKAQAWEDCVKGFLDAEVKPLWPKGWMQARTLFKESRRGHGHLTSILAKKKVMAPSKIKVKESSTKPDKKVSVPSGQIGGPIALPSDHQTGGLSIGASSRELPSQASGGLANPPPVNLEDSLDEDLIRNPASSVEAVSKELAALNSRAAGNSEFTLPAPSKAPAEKVGGVLCTEEKRNFAKPSPSAPPPASSLQSPLNFLAEQALALGQSSQEKKPES-SGYKELSCQAPLNKGLPEVHQSKAKHHSLPRTSHGPQVAVPVPGPQVKVFHAGTQQQKNFTPPSPFANKLQGPKASPTQCHRSLLQLVKTAAKGQGFHPSAPATSGGLSASSSSSHKTPASSSSALSHPAKPHSVSSAGSSYKNNPFASSISKHGVSSGSSSSGG-TPVQSSVSGSLVPGIQPPSVGQATSRPVPSSAGKKMPVSQKLTLVAPPGGPNGDSSGGTQGVAKLLTSPSLKPSAVSSVTSSTSLSKGASGTVLLAGS---SLMASPYKSSSPKLSGAMSSNSLGIITPVPIPVHVLSFSADSSAKAGVSKDAIVTGPAPGSFHHGLGHSLLAGLHSSPPHAAPLPHAAVPTHIPQSLPGASQLHGKGPAVPRKL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P25992-1", "uniprot_id": "YEMA_DROME", "id": "P25992-1", "name": "yemanuclein", "aln": "MSKGGEHKRVTLTSIIQGDAGFSRFGSNILEPDAASAAPDNSSKPTTKTAKCIRIKLDLFETDSNKYPEFNYSRLLYLEKKKTKKLKQVSTTNGSASTDPFADNDDD---VARIVKELEAKYGNSYATGRGKSKKDDYRDIGMGYDESDSFIDNTEAYDEIIPEEAETLEGGFYINCGALEFKNLTKKSYTTRTDAIIKMPERSRKR----------------MVSSSSESSSSSSGDDDENDDGNNEEDDESDSEDDSEENDESDSEDDSESESLEDEDSAATAKSSSKYKDNHQAKRAKVIVTGKSKPSSSSLTSGKKPPTKPITTSSSSNSPRPSTVEISDTEDGQDPIQT-------QPSSQLQSLPQ-----SQAQAQALKKVVKTTTVKDMLKAKRDSFLKSQSGTAAVKG-VGNGELKCVSTDVSSSDSSDMESEHGRADRQAG------------QHGKDGQENLRTADTLLPTTLDADIVTAVNSFKEAVKSRDMCG-----------------KKFNLDVKLSPLLLRVYEAVLCTDRNERN----------MVFSHIEYQLQLPKYYMLRKGKQVRAKEEKRKSTIMLEKLRRAVAVVMPKAVANYETELRTFAEQAAADVNSELPPKMPRKKFQWTSELRHLLYDVYQARWTS----------YAFLAKRKESLEEFINWYLKEKVVELWPPGWMRLDELQREITRYKNAKLKAKEKPKAPPASASPKPVGVVSAPEQMPPASSYLKAVEDPRSRGNSDTDSATSASSNSLKRKLKEMPKQTSKPPKKKVAKQVPLQPQLTPHPQFQLAPAAT---AAVSIPAISNNNNHLP------HLDTLLSMPSTSAQAAALNAAAVAAASTVLDLASPSRKIDLNTSNNFYNLITAASLAASG----------NPSPHSGDGQAKVIVGARPSPHVIN---LDDYQCTSDILQTSKQLAATTTVITAISKAAQTTSVARESSSESDG-VEIVGVFPASKPQKKVQSKPKNKTQNRGRSSLGAVGQVNGSLGYSANNMYIYNSPRTLG-----------------PVYDLTDPHIMKTMSNLKEMEKQFIQAAFSPNSVKGASGGMGSSAPSTPTRQ-----------------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .* :** :**: * : : :. ... :. : :* .:**.* ***.* :: *** *..*: : *.* *: ...: *** *::.: * :.:::* *** .. * *.: :* *:* ***********:*****::* . * ******.*:*:*:: ::.. .: * *:: : : ..*.:*. *.:* * . ::::.. *.: . * .: :.*.:::.: *:....*... .:: : :. :: *..... * :.. : . . * *. : * :**.*.: . **** :.** : *** : . : * : : .. :*. : * :.. : .* ::: :..*..: :: : : * *: *:: . : : :*.:.. ::. *: : :*. ***: : :: ** :* : * : *** * . * : ** :* : .::. : : * :* * : .. : :. : : :. .. . * .. :. :. *. :. . . :: : .*:: . : : . : : : .. . ::: : *:.::* *.. :.:* :: . .: . .. ..: :. :. :.. .*.: : *: ..:* . :.: * . .* **.:: *.* .: *: *: : * ::*.: .*:*:. .::.: *::. :*.::* ..*. : : . . :: * . * *. . : * :. : . * .* :*: .::: .::: .: . ...:*.* .: *. : :* . * .. ..: . :.: *:* . . * ..*: * * .:. *: . . : . .:* . :. .*: **.* :.. ", "identical_positions": 171, "similar_positions": 383, "identity": "14.84%" }, { "cls_id": "homologset.agr.MGI:1891338", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9Z0G2-1", "uniprot_id": "SRPK3_MOUSE", "id": "Q9Z0G2-1", "name": "SRSF protein kinase 3", "aln": "--------------------------------------------------------MSANAGGSG-SVDCGG--------------------------------------------SSSSSQTS-----------------------------------CGPESSGSELTPATPAPRLLQG-------------------------------LLGSDDEEQEDPKDYCKGGYYPVKIGDLFN-GRYHVVRKLGWGHFSTVWLCWDIQRKRFVALKVVKSAGHYTETAVDEIKLLKCVRDSDPSDPK---RETIVQLIDDFRISGVNGVH--VCMVLEVLGHQLLKWIIKSNYQGLPVPCVKSIVRQVLHGLDYLHTKCKIIHTDIKPENILLCVGDAYIRRLAAEATEWQQSGAQPPSRSTVSTAPQEVL---------------IGKLSKNKRKKMRRKRKQQKRLLEERLRDLQRLEAMEAAVQAEDSS-------------------------------------------------SRLERG-------------SGSTSSSGCHPEGTRAGPSPASSS--------------------PVP-GGERSLSPS----------------------SQTSGFSGSLFSTASCSILSGSSNQRETGGLLSPSTPFGASNLLVNPLEPQNADKIKIKIADLGNACWVHKHFTEDIQTRQYRAVEVLIGAEYGPPADIWSTACMAFELATGDYLFEPHSGEDYSRDEDHIAHIVELLGDIPPAFALSGRYSREFFNRRGELRHIPNLKHWGLYEVLMEKYEWPLEQATQFSAFLLPMMEYIPEKRASAADCLQHPWLNP----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A0G2KAH6-1", "uniprot_id": "A0A0G2KAH6_RAT", "id": "A0A0G2KAH6-1", "name": "SRSF protein kinase 3", "aln": "---------------------MHWPRLGPTGTVVQCTRALGCDT-----------RMSASAGGSG-GMDCGG--------------------------------------------SSSSSQTS-----------------------------------CGPESSSSELAPATPAPRLLQG-------------------------------LLGSDDEEQEDPKDYCKGGYYPVKIGDLFN-GRYHVVRKLGWGHFSTVWLCWDIQRKRFVALKVVKSAGHYTETAVDEIKLLKCVRDSDPSDPK---RETIVQLIDDFRISGVNGVRPDVCMVLEVLGHQLLKWIIKSNYQGLPVPCVKSIVRQVLHGLDYLHTKCKIIHTDIKPENILLCVGDAYIRRLAAEATEWQQSGAQPPSRSTVSTAPQEVL---------------TGKLSKNKRKKMRRKRKQQKRLLEERLRDLQRLEAMEAAVQTEDSS-------------------------------------------------SRLEQG-------------SGSTSSSGCHPEGTRAGPSPASSS--------------------PVPTGGERSLSPS----------------------SQTSGFSGSLFSTASCSVLSGSSNQRETGGLLSPSTPFGASNLLVNPLEPQNADKIKIKIADLGNACWVHKHFTEDIQTRQYRAVEVLIGAEYGPPADIWSTACMAFELATGDYLFEPHSGEDYSRDEDHIAHIVELLGDIPPAFALSGRYSREFFNRRGELRHIHNLKHWGLYEVLMEKYEWPLEQATQFSAFLLPMMEYIPEKRASAADCLQHPWLNP----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9UPE1-1", "uniprot_id": "SRPK3_HUMAN", "id": "Q9UPE1-1", "name": "SRSF protein kinase 3", "aln": "--------------------------------------------------------MSASTGGGGDSGGSGG--------------------------------------------SSSSSQAS-----------------------------------CGPESSGSELALATPVPQMLQG-------------------------------LLGSDDEEQEDPKDYCKGGYHPVKIGDVFN-GRYHVVRKLGWGHFSTVWLCWDIQRKRFVALKVVKSAGHYTETAVDEIKLLKCVRDSDPSDPK---RETIVQLIDDFRISGVNGVH--VCMVLEVLGHQLLKWIIKSNYQGLPVPCVKSIVRQVLHGLDYLHTKCKIIHTDIKPENILLCVGDAYIRRLAAEATEWQQAGAPPPSRSIVSTAPQEVLQ--------------TGKLSKNKRKKMRRKRKQQKRLLEERLRDLQRLEAMEAATQAEDSG-------------------------------------------------LRLDGG-------------SGSTSSSGCHPGGARAGPSPASSS--------------------PAP-GGGRSLSAG----------------------SQTSGFSGSLFSPASCSILSGSSNQRETGGLLSPSTPFGASNLLVNPLEPQNADKIKIKIADLGNACWVHKHFTEDIQTRQYRAVEVLIGAEYGPPADIWSTACMAFELATGDYLFEPHSGEDYSRDEDHIAHIVELLGDIPPAFALSGRYSREFFNRRGELRHIHNLKHWGLYEVLMEKYEWPLEQATQFSAFLLPMMEYIPEKRASAADCLQHPWLNP----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8N7TFD0-1", "uniprot_id": "A0A8N7TFD0_DANRE", "id": "A0A8N7TFD0-1", "name": "non-specific serine/threonine protein kinase", "aln": "-------------MSSCSRSHFNRTSCCQYSAEPQCACSEPTEANVREVTAVPMISMNVSSSDNNLPQNSHGKKQKKKNKKHRKAAVAAAVEISSLELGPQIPSSDELCHILTIHRSATPPESSPTPPLNLSQSPPDLQPPAPIPHSIPITVVPSPVVVSSPETPSTPIAPSLGLPSILSSTPPTPQAPSNQPTPPQALSPPPPDFSPPPAELLGSDDEEQENPSDYCKGGYYPVKIGDLFN-GRYHVVRKLGWGHFSTVWLCWDLQRKRFVALKVVKSAQHYTETALDEIKLLKCVRDSDPTDSK---RERLVQLIDDFKISGVNGVH--VCMVLEVLGHQLLKWIIKSNYMGLPLICVKSILRQVLEGLDYLHTKCKIIHTDIKPENILLEVNEVYVRRLAAEATIWQKAGAPPPSGSSVSTAPREKQ---------------MGKMSKNKKKKLKRKAKRQQQLLDERLIDLQRMEELDGVLPSDASGNTR--------------------------------------------ALWRLSEDEEDNVKH------AQTNGNGALNKQSPESGSSWLEES--------------------CNGYGPLRFSSPG----------------------SGLSGLSGSILSATSESALSTLSGYSTERSLLSPNS-YSAADFLVNPLESQNADKISIKIADLGNACWVHKHFTEDIQTRQYRALEVLIGAEYGPPADIWSTACMAFELATGDYLFEPHSGEDYTRDEDHIAHIIELLGAIPPHFALSGRYSREYFNRRGELRHIANLKPWGLFEVLLEKYEWPLDQAAQFSDFLLTMLEFIPEKRATAAQCLQHPWINS----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A6M3Q7C8-1", "uniprot_id": "A0A6M3Q7C8_DROME", "id": "A0A6M3Q7C8-1", "name": "non-specific serine/threonine protein kinase", "aln": "-MNKADVNRRVLAIQAKKKRHKNRKRGKQNGTNPQ-EQSNSSQNQNPKPSSNPIPEPNRSSENLQAPDNANNSHLN----------------------------------------APSSAAFS---------------------------------KATATATASTSSGGSAGTPDQYQPPKKTQAKAKPNTQKEHQQQPPRSSSNESYESETFSDNEDQELMEDYCKGGYHPVNIGDLFH-DRYHVIRKLGWGHFSTVWLCWDLQAMGYVAIKIVKSAPHFAETARDEIKILKTVRETDPSNPR---RHKTVQMLDDFKITGVNGTH--ICMVFEVLGDNLLKLIRKSNYRGIPLANVKTITRQVLEGLDYLHTCCKIIHTDIKPENVLLCVDEPHVRSLATEATQLYCMNSKMYP-SLVSRAPKEYREPP-----------ITGKMSKNRKKKLKKKAKKRMELFKQQRDYLEQADGQGAINPNEVQNGDAGISDADEYFDANSVEDNVHVAAGQPSRKQREERKAPPEQSEEAQEQDPLTEGTDKAKKKKKKKNKNKSNQSKGQQPPQLENSTSSAESSSALKSQQANGSNSTTNNKSNTNSSGTLKGQSNGKKMPLRPKQEKQGSNHQLNNNNSKPNSNSDSKISSGSVENTSSATNGPHSNSTLPTPPPPPQAKHKAKKDPALDECNVHVKIADLGNACWVDRHFTEDIQTRQYRSLEVIIGAGYNTSADIWSTACMVFELATGDYLFEPHSGESYTRDEDHLAHIIELLGPIPREILLNGTYAAKSFTRSCELRNISGLKPWGLMDVLLEKYEWSQKDAASFASFLTPMLEFDPNKRATAAECLQHPWLRXDTMQPGCWLRATQPATADGDGGALAGTGTGKGTRARATALKGGSPAVPADGEVGRGYIESSASVATLASISSIASTSAAAMAALKARPYLVAPFVTTASAPPTPHPHASISTSTARTAPATPTRRRIAPEDDLNLVEDLDVALAQIEDTQTHTKNKSQRFFWRKALRRVFQRRKXRRRRQDLPRWHRPARRCRRRNLAERVRRICACCAYGQILLRAARVALLSCIRWRTRGNIRNNNFYFSNH", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q03656-1", "uniprot_id": "SKY1_YEAST", "id": "Q03656-1", "name": "Serine/threonine-protein kinase SKY1", "aln": "MGSSINYPGFVTKSAHLADTSTDASISCEEATSSQEAKKNFFQRDYNMMKKAPAPTKSKLSLALQTSKSSSSAN------------------------------------------GTVQEDTSS--------------------------------KTEDFSTKSIKKKPDSGVESHVSIQSDS--------------GPQSDSDLDSDSSISSCDERNEESLKDYRPGGYHPAFKGEPYKDARYILVRKLGWGHFSTVWLAKDMVNNTHVAMKIVRGDKVYTEAAEDEIKLLQRVNDADNTKEDSMGANHILKLLDHFNHKGPNGVH--VVMVFEVLGENLLALIKKYEHRGIPLIYVKQISKQLLLGLDYMHRRCGIIHTDIKPENVLMEIGDVEGIVQMVEALDKQKREAKRLQRHVSRSSDITANDSSDEKWAECQTSMPCGSSSNSKSRSIEKDLSKRCFRRPRRHTIITGSQPLPSPISSSNFFEMR--------------------------------------------AHFCGSSHNSFSSVSGNRNIPSSINNNSINNGIGIKNSNNSFLNSVPHSVTRMFINEDSNDNNNNDNSKNKNNNNNNS--------------NNNNNEDIMNTPLHEEQLADSLSTFDISNISQSSDTNGPYISNTMDSNSNVSTDINSP--ENLIQIKIADLGNACWYDEHYTNSIQTREYRSPEVLLGAPWGCGADIWSTACLIFELITGDFLFEPDEGHSYTKDDDHIAQIIELLGELPSYLLRNGKYTRTFFNSRGLLRNISKLKFWPLEDVLTEKYKFSKDEAKEISDFLSPMLQLDPRKRADAGGLVNHPWLKDTLG--------------------------MEEIRVPDRELYGSGSDIPGWFEEVRDHKRH----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . : .. . .. * : . . .*:.::* .** ***:*. *: :: ** ::*************. *: .**:*:*:. ::*:* ****:*: *.::* :. . ::::*.*. .* **.: : **:****.:** * * :: *:*: ** * :*:* ****:* * **********:*: :.: .** : : *. *:.: :.:.:. .:: .: : : . . . . : . . . .* . . . . . . .. * * : . . . :. .. . : :********** ..*:*:.****:**: **::** :. ********: *** ***:****..*..*::*:**:*:*:**** :* : .* *: *. **:* ** * * :** ***::. .:* .:: ** .*:: *.*** *. ::***:. ", "identical_positions": 164, "similar_positions": 161, "identity": "14.88%" }, { "cls_id": "homologset.agr.MGI:1891340", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0ACD6B759-1", "uniprot_id": "A0ACD6B759_DANRE", "id": "A0ACD6B759-1", "name": "phosphatidate phosphatase", "aln": "----------------------MIAEDQVDEYDERFGPNETSWTWSQTMNYVGQLAGQVFVQVKELYRGLNPATLSGCIDVIVVRQPDGTLQCSPFHVRFGKMGVLRSREKVVDIEINGEPVSLHMKLGENGEAFFVKETEDDGEMVPSYLATSPIISEGSALMQAQMGKG-TSRLSESGNGTTIQTLGPMQPPGDSSIMKKRRKRRRKSKVDSMKREDNGD-SEDEDMFPIDMSSDDDDTEASGSRAMSHDL------------FAEQLKGASNTYMQSERNWAGVQSTGLEKTCSLPIPTNTGLSISCPQQSAMFHRTDSPNGSLPSTPKSDSELLDSQRNKG-KPDNPEMLWTWGELPHAAKPSFRQPLPEPMVVTPKSIPRSESTHFRAITG-------DGMVESRGSVMYVPDIRTEEATSTPVEEVEPISVVAHLITELEDGRHSPGAHAI--SKTDSPSKRKDKRSPHLGSDGVYLDDITELEPEVAALYFPKSDGA---TSLRSGADSRSANQSPQSVGSSGMDSGVESFSDQLGDLPHIAISLCGGLSENREITREEFEERAISYQEFADNPAIIDDPNLVVKIGTKYYNWTTAAPIVLAMQVFQKPLPT--------------------------ATVENIMKEKMPKKGGRWWFSWRGRNS----SSKS--ESAADQIECGDESIRTGSVSRLKDESSSSEDDSGGAKQIAVMNQPEVLHSSGGHCYRKTLRLSPEQLASLNLKDGPNDVVFSVTTQYQGTCRCEGTIYLWNWDDKIVISDIDGTITRSDT----LGHILPTLGKDWTHQGIARLYHRVSQNGYKFMYCSARAIGMADMTRGYLHWVNERGTMLPMGPVLLSPSSLFSAFHREVIEKKPEKFKIECLTDIKNLFYPNAEPFYAAFGNRATDVYSYKEVGVPLNRIFTVNPKGELIQEHAKTNISSYGRLCEVVDHVFPLLIRGNTTDFPCSDTFSQFTFWREQLPEVEKQDQQA-----", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8M9P333-1", "uniprot_id": "A0A8M9P333_DANRE", "id": "A0A8M9P333-1", "name": "phosphatidate phosphatase", "aln": "MQREDEEIENDTKSELKVQTEEEEEEEEEEEEDEEDEAITSSWSWTQTMNYVGQLAGQVFVQVKELYRGLNPATLSGCIDVIVVRQPDGALVCSPFHVRFGKMGVLRSREKVVDIEINGEPVNLHMKLGENGEAFFVKETEDDQEVIPPYLATSPIPSDGGVMMGSSN---------------------------ENSLMKKRRKRRKKCRMEGVKREESVE-FSDEELFNMDINSSE---QSDQNRDLSSGG------------SSTGNK-PNTSYAHSDGDWSPVHS---------------------------------LNASRPCSPKSDSELLCKKHQ-----EDSAMSWSWGELPQTAKPSFLPAKPTALPSCPLSIPVSDNTHFRVITES------DTHQHHRNRTLYADGQTNAEKECEKQHMIR----RASVMSETEVGGANTGPRPQ--NKTESSLKRKDKKSRHLGSDGVYLDDIKDLEPEVAALYFPKSG------SERYGEDR--VTVSPQSMCSSGADSGVDSY-----DLPSMAISLCGGLTENRDITKEHFQQKSVSFQQFSDNPSIINDPNLVVKIGSKYYNWSTAAPIMLAMQAFQKPLPK--------------------------ATVERLTKEKMPRNRGRWWFSWRGRTS----SSKQDLTSGGSACAAGDENIKN----RRKEESSSSDEDLS-AKQTPAAVTIDSAPLGGGVTYQKTLRLSSEQLVSLQLKDGANDVVFSVTTQYQGTCRCEGTIYLWNWDDKIIISDIDGTITRSDK----LGHILPTLGKDWTHQGIAHLYHNVSQNGYKFLYCSARAIGMADMTRGYLHWVNERGTMLPQGPVLLSPSSLFSALHREVIEKRPEKFKVACLTDIRNLFLPNTEPFYAAFGNRDTDVLSYKEVGVPLNRIFTVNPKGELIQEHAKTNISSYVRLGEVVDHVFPLLKRSSSSDFPCSDTFSQFTFWREQLPLLDGQIANTINTT-", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q91ZP3-1", "uniprot_id": "LPIN1_MOUSE", "id": "Q91ZP3-1", "name": "Phosphatidate phosphatase LPIN1", "aln": "------------------------------------------------MNYVGQLAGQVFVTVKELYKGLNPATLSGCIDIIVIRQPNGSLQCSPFHVRFGKMGVLRSREKVVDIEINGESVDLHMKLGDNGEAFFVQETDNDQEIIPMYLATSPILSEGAARMESQLKRNSVDRIRCLDPTTAAQGLPPSDTPSTGSLGKKRRKRRRKAQLDNLKRDDNVNSSEDEDMFPIEMSSDEDTAPMDGSRTLPNDVPPFQDDIPKENFPSISTHPQSASYPSSDREWSPSPSSLVDCQRTPPHLAEGVLSSSCPLQSCHFHASESPSGSRPSTPKSDSELVSKSADRLTPKNNLEMLWLWGELPQAAKSSSPHKMKESSPLG--SRKTPDKMNFQAIHSESSDTFSDQSPTMARGLLIHQSKAQTEMQFVNEEDLESLGAAAPPSPVAEELKAPYPNTAQSSSKTDSPSRKKDKRSRHLGADGVYLDDLTDMDPEVAALYFPKNGDPGGLPKQASDNGARSANQSPQSVGGSGIDSGVESTSDSLRDLPSIAISLCGGLSDHREITKDAFLEQAVSYQQFADNPAIIDDPNLVVKVGNKYYNWTTAAPLLLAMQAFQKPLPK--------------------------ATVESIMRDKMPKKGGRWWFSWRGRNATIKEESKPEQCLTGKGHNTGEQPAQLGLATRIKHESSSSDEEHAAAKPSGSS----HLSLLSNVSYKKTLRLTSEQLKSLKLKNGPNDVVFSVTTQYQGTCRCEGTIYLWNWDDKVIISDIDGTITRSDT----LGHILPTLGKDWTHQGIAKLYHKVSQNGYKFLYCSARAIGMADMTRGYLHWVNERGTVLPQGPLLLSPSSLFSALHREVIEKKPEKFKVQCLTDIKNLFFPNTEPFYAAFGNRPADVYSYKQVGVSLNRIFTVNPKGELVQEHAKTNISSYVRLCEVVDHVFPLLKRSHSCDFPCSDTFSNFTFWREPLPPFENQDMHSASA--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "F7FDH2-1", "uniprot_id": "F7FDH2_RAT", "id": "F7FDH2-1", "name": "phosphatidate phosphatase", "aln": "---------------------------MEEKWSPHRRRGFLQATKVQTMNYVGQLAGQVFVTVKELYKGLNPATLSGCIDIIVVRQPNGSLQCSPFHVRFGKMGVLRSREKVVDIEINGESVDLHMKLGDNGEAFFVQETDNDQEVIPMYLATSPILSEGASRMESQLKRNSVDRIRGLDPTTAAQGLPPSDTPSTGSLGKKRRKRRRKAHLDNLKRDDNVNTSEDEDMFPIEMSSDEDTALMDGSRALPNDVPPFQDDIPKENLPSISTYPQSASYPNSDREWSPSPSSLVDCQRTPPHLAEGVLSSSCPLQSCHFHASESPSGSRPSTPKSDSELVSKSADRLTPKNNLEMLWLWGELPQAAKSSSPHKMKDSSPLG--GRKMADKIHFQTIHSESSDTFSDQSPTMARGLLIHQSKAQTEMQFVNEEDLEALGAAAPPLSVAEELKAPASSTAQTSSKSDSPSRKKDKRSRHLGADGVYLDDLTDMDPEVAALYFPKNGDPGGLPKQASDNGARSANQSPQSVGSSGIDSGVESTSDSLRDLPSIAISLCGGLSDHREITKDAFLEQAVSYQQFADNPAIIDDPNLVVKIGNKYYNWTTAAPLLLAMQAFQKPLPKSSCLSYLHMILDAIRFCLSKIFSPPTATVESIMRDKMPKKGGRWWFSWRGRNATIKEESKPEQGLPGKGHNTGEQPAQLGLTTRIKHESSSSDEEHSATKPSSSS----HLSLLSNVSYKKTLRLTSEQLKSLKLKNGPNDVVFSVTTQYQGTCRCEGTIYLWNWDDKVIISDIDGTITRSDT----LGHILPTLGKDWTHQGIAKLYHKVSQNGYKFLYCSARAIGMADMTRGYLHWVNERGTVLPQGPLLLSPSSLFSALHREVIEKKPEKFKVQCLTDIKNLFFPNTEPFYAAFGNRPADVYSYKQVGVSLNRIFTVNPKGELVQEHAKTNISSYVRLCEVVDHVFPLLKRSHSCDFPCSDTFSNFTFWREPLPPFENQDVHSASA--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q14693-1", "uniprot_id": "LPIN1_HUMAN", "id": "Q14693-1", "name": "Phosphatidate phosphatase LPIN1", "aln": "------------------------------------------------MNYVGQLAGQVFVTVKELYKGLNPATLSGCIDIIVIRQPNGNLQCSPFHVRFGKMGVLRSREKVVDIEINGESVDLHMKLGDNGEAFFVQETDNDQEVIPMHLATSPILSEGASRMECQLKRGSVDRMRGLDPSTPAQVIAPSETPSSSSVVKKRRKRRRKSQLDSLKRDDNMNTSEDEDMFPIEMSSDEAMELLESSRTLPNDIPPFQDDIPEENLSLAVIYPQSASYPNSDREWSPTPS---------------------------------PSGSRPSTPKSDSELVSKSTERTGQKN-PEMLWLWGELPQAAKSSSPHKMKESSPLS--SRKICDKSHFQAIHSESSDTFSDQSPTLVGGALLDQNKPQTEMQFVNEEDLETLGAAAPLLPMIEELKPPSASVVQTANKTDSPSRKRDKRSRHLGADGVYLDDLTDMDPEVAALYFPKNGDPSGLAKHASDNGARSANQSPQSVGSSGVDSGVESTSDGLRDLPSIAISLCGGLSDHREITKDAFLEQAVSYQQFVDNPAIIDDPNLVVKIGSKYYNWTTAAPLLLAMQAFQKPLPK--------------------------ATVESIMRDKMPKKGGRWWFSWRGRNTTIKEESKPEQCLAGKAHSTGEQPPQLSLATRVKHESSSSDEERAAAKPSNAG----HLPLLPNVSYKKTLRLTSEQLKSLKLKNGPNDVVFSVTTQYQGTCRCEGTIYLWNWDDKVIISDIDGTITRSDT----LGHILPTLGKDWTHQGIAKLYHKVSQNGYKFLYCSARAIGMADMTRGYLHWVNERGTVLPQGPLLLSPSSLFSALHREVIEKKPEKFKVQCLTDIKNLFFPNTEPFYAAFGNRPADVYSYKQVGVSLNRIFTVNPKGELVQEHAKTNISSYVRLCEVVDHVFPLLKRSHSSDFPCSDTFSNFTFWREPLPPFENQDIHSASA--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P32567-1", "uniprot_id": "PAH1_YEAST", "id": "P32567-1", "name": "Phosphatidic acid phosphohydrolase 1", "aln": "------------------------------------------------MQYVGRALG----SVSKTWSSINPATLSGAIDVIVVEHPDGRLSCSPFHVRFGKFQILKPSQKKVQVFINEKLSNMPMKLSDSGEAYFVFEMGDQVTDVPDELLVSPVMSATSSPPQSPE---------------TSILEGGTEGEGEGENENKKKEKKVLEEPDFLDINDTGDSGSKNSETTGSLSPTESSTTTPPDSVEERKLVEQRTKNFQQKLNKKLTEIHIPSKLDNNGDLLLDTEG--------------------------------YKPNKNMMHDTDIQLKQLLKDEFGNDSDISSFIKEDKNGNIKIVNPYEHLTDLSPPG-TPPTMATSGSVLGLDAMESGSTLNSLSSSPSGSDTEDETSFSKEQSSKSEKTSKKGTAGSGETEKRYIRTIRLTNDQLKCLNLTYGENDLKFSVDHG-KAIVTSKLFVWRWDVPIVISDIDG---------TITKSDALGHVLAMIGKDWTHLGVAKLFSEISRNGYNILYLTARSAGQADSTRSYLRSIEQNGSKLPNGPVILSPDRTMAALRREVILKKPEVFKIACLNDIRSLYFE-----------------------------DSDNEVDTEEKSTPFFAGFGNRITDALSYRTVGIPSSRIFTINTEGEVHMELLELAGYRSSYIHINELVDHFFPPVS-------LDSVDLRTNTSMVPGSPPNRTLDNFDSEITSGRKTLFRGNQ-EEKFTDVNFWRDPLVDIDNLSDISNDDSDNIDEDTDVSQQSNISRNRANSVKTAKVTKAPQRNVSGSTNNNEVLAASSDVENASDLVSSHSSSGSTPNKSTMSKGDIGKQIYLELGSPLASPKLRYLDDMDDEDSNYNRTKSRRASSAAATSIDKEFKKLSVSKAGAPTRIVSKINVSNDVHSLGNSDTESRREQSVNETGRNQLPHN-SMDDKDLDSRVSDEFDDDEFDEDEFED", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *:***: * *.: : .:*******.**:**:.:*:* * **********: :*:. :* *:: ** : .: ***.:.***:** * :: :* * .**: * . . .. :*::::: . : :. ::. : ..:. .:.. : . : .: : . . . .:* :* : . .: : . . . : : : . . . . . : .. * * . * ..: ..: :*. : .. : . . ** . : * . : : : *:. : . . .:: :.* *:. . :. : : .. . : .:: ::. : . . .: :: .: .* : . : : .** . : : . :.. : . . . *.: .::. . .* ::*. * : * * :: * . *:..*. . :. .: ::. : .*:: : : *:. : : . : : .: . *. ..: . : ::: : . : * : :: ::: : . : . : : . : .... .::.: :* :. .: : . ::* . ::.: : . .: : . ", "identical_positions": 80, "similar_positions": 261, "identity": "7.92%" }, { "cls_id": "homologset.agr.MGI:1891341", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZYB4-1", "uniprot_id": "D3ZYB4_RAT", "id": "D3ZYB4-1", "name": "phosphatidate phosphatase", "aln": "-------------------------------------MNYVGQLAGQVLVTVKELYKGINQATLSGCIDVVVVRQQDGSYQCSPFHVRFGKLGVLRSKEKVIDIEINGSAVDLHMKLGDNGEAFFVEETEEEYEKLPAYLATSPIPTEDQFFKHIDPPLVKSSGNERPPQSSDVSHTLESEAVFTPSSVKKKKRRRKKCKQDNRKEEQ------AASPVAEDVGDVAVSSDDEKRAQAARGSSNASLKEEDYKEPPPFHSGDNYPLSDGDWSPLET-SYPQTVCPKSDSELEVKPSESLLRSESHMEWTWGGFPESTKVSKRERYDYHPRTATITPSENTHFRVIPSEDSLIREVEKDATVEDTTCTIVKPKPRALCKQLSDAAS-TELPESPLEAPQISSTLDADPVP-SPSAEAPSE---PKPAAKVDSPTKRKGVHKRSQHQGPDDIYLDDLKALEPEVAALYFPKSDTDPGSRQWPESDTFSGSQSPQSVGSAAADSGTECLSDSAMDLPDVTLSLCGGLSENGEISKEKFMEHIITYHEFAENPGLIDNPNLVIRIYNRYYNWALAAPMILSLQVFQKSLPKATVESWVKDKMPKKSGRWWFWRKK-ESMTKQLPETKEGKSEVPPANDLPSGTEEPVSARPAEN-DTSSDEGSQELEETIKVDP--ISMETLSHCGTASYKKSLRLSSDQIAKLK-LHDGPNDVVFSITTQYQGTCRCAGTIYLWNWNDKVIISDIDGTITKSDALGQILPQLGKDWTHQGIARLYHSINENGYKFLYCSARAIGMADMTRGYLHWVNDKGTILPRGPLMLSPSSLFSAFHREVIEKKPEKFKIECLNDIKNLFAPSR-QPFYAAFGNRPNDVYAYTQVGVPDCRIFTVNPKGELIQERTKGNKSSYHRLSELVEHVFP-LLNKEQNSAFPCPEFSSFCYWRDPIPDVDLDDLA-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q99PI5-1", "uniprot_id": "LPIN2_MOUSE", "id": "Q99PI5-1", "name": "Phosphatidate phosphatase LPIN2", "aln": "-------------------------------------MNYVGQLAGQVLVTVKELYKGINQATLSGCIDVVVVRQQDGSYQCSPFHVRFGKLGVLRSKEKVIDIEINGSAVDLHMKLGDNGEAFFVEETEEEYEKLPAYLATSPIPTEDQFFKHIETPLVKSSGNERPAQSSDVSHTLESEAVFTQSSVKKKKRRRKKCKQDNRKEEQ------AASPVAEDVGDVGVSSDDEKRAQAARGSSNASLKEEDYKEPSLFHSGDNYPLSDGDWSPLET-TYPQAVCPKSDSELEVKPSESLLRSEPHMEWTWGGFPESTKVTKRERYDYHPRTATITPSENTHFRVIPSEDSLIREVEKDATVEDTTCTIVKPKPRALCKQLSDAAS-TELPESPLEAPQISSLLDADPVP-SPSAEAPSE---PKPAAK-DSPTKKKGVHKRSQHQGPDDIYLDDLKALEPEVAALYFPKSDTDPGSRQWPESDTFSGSQSPQSVGSAAADSGTECLSDSAMDLPDVTLSLCGGLSENGEISKEKFMEHIITYHEFAENPGLIDNPNLVIRIYNRYYNWALAAPMILSLQVFQKSLPKATVESWVKDKMPKKSGRWWFWRKK-ESMIKQLPETKEGKSEVPPANDLPSNAEEPTSARPAEN-DTSSDEGSQELEESIKVDP--ITVETLSHCGTASYKKSLRLSSDQIAKLK-LHDGPNDVVFSITTQYQGTCRCAGTIYLWNWNDKVIISDIDGTITKSDALGQILPQLGKDWTHQGIARLYHSINENGYKFLYCSARAIGMADMTRGYLHWVNDKGTILPRGPLMLSPSSLFSAFHREVIEKKPEKFKIECLNDIKNLFAPSR-QPFYAAFGNRPNDVYAYTQVGVPDCRIFTVNPKGELIQERTKGNKSSYHRLSELVEHVFP-LLSKEQNSAFPCPEFSSFCYWRDPIPDLDLDDLA-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q92539-1", "uniprot_id": "LPIN2_HUMAN", "id": "Q92539-1", "name": "Phosphatidate phosphatase LPIN2", "aln": "-------------------------------------MNYVGQLAGQVIVTVKELYKGINQATLSGCIDVIVVQQQDGSYQCSPFHVRFGKLGVLRSKEKVIDIEINGSAVDLHMKLGDNGEAFFVEETEEEYEKLPAYLATSPIPTEDQFFKDIDTPLVKSGGDETPSQSSDISHVLETETIFTPSSVKKKKRRRKKYKQDSKKEEQ------AASAAAEDTCDVGVSSDDDKGAQAARGSSNASLKEEECKEPLLFHSGDHYPLSDGDWSPLET-TYPQTACPKSDSELEVKPAESLLRSESHMEWTWGGFPESTKVSKRERSDHHPRTATITPSENTHFRVIPSEDNLISEVEKDASMEDTVCTIVKPKPRALGTQMSDPTSVAELLEPPLESTQISSMLDADHLPNAALAEAPSE---SKPAAKVDSPSKKKGVHKRSQHQGPDDIYLDDLKGLEPEVAALYFPKSESEPGSRQWPESDTLSGSQSPQSVGSAAADSGTECLSDSAMDLPDVTLSLCGGLSENGEISKEKFMEHIITYHEFAENPGLIDNPNLVIRIYNRYYNWALAAPMILSLQVFQKSLPKATVESWVKDKMPKKSGRWWFWRKR-ESMTKQLPESKEGKSEAPPASDLPSSSKEPAGARPAEN-DSSSDEGSQELEESITVDP--IPTEPLSHGSTTSYKKSLRLSSDQIAKLK-LHDGPNDVVFSITTQYQGTCRCAGTIYLWNWNDKIIISDIDGTITKSDALGQILPQLGKDWTHQGIAKLYHSINENGYKFLYCSARAIGMADMTRGYLHWVNDKGTILPRGPLMLSPSSLFSAFHREVIEKKPEKFKIECLNDIKNLFAPSK-QPFYAAFGNRPNDVYAYTQVGVPDCRIFTVNPKGELIQERTKGNKSSYHRLSELVEHVFP-LLSKEQNSAFPCPEFSSFCYWRDPIPEVDLDDLS-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M2BAN1-1", "uniprot_id": "A0A8M2BAN1_DANRE", "id": "A0A8M2BAN1-1", "name": "phosphatidate phosphatase", "aln": "MKRLHSRTEAETTGTEEDNSEQDESSSLRASWSWSDTMNYVGQLAGQVLVTMKELYKGINQATLSGCIDVVVVRQKDGTYQCSPFHVRFGKLGVLRSKEKVIDIEINGEPVDLHMKLGDNGEAFFVQETEEQNEIVPAHLATSPIPTESHLFWIGGDHRSSQNLDDDPLDPEDP----PDRPVASTGGAKKKKKRRKKHKGDPRREEFTPPAVISSTPSTDEIFEMDLSSDED-AISNTRSSSVSTVKESEPKLPTIRHSLDSYPYSDGDWSPSDSHAMSEAFSPKSDSELVVRPSESLLKMESHMQWTWGEFPESTRVSKKEK-IELPKTVTITPSENTHFRVILSSEAMETD-EREPTSGTPSCTIVKPEPRTPVTPKTPTESELETMPCEVLTSTPSDILTAAPTSPAAVSAAPLGGDIGDVGSKTDSPSKKKGVPKRSQHQGPEDIYLDDLNVLEPDVAARYFPKSDSDAGSKHWMDSGMHSGSQSPQSVGSAAADSGTECLSDSASDLPDVTLSLCGGLSENGEISKEKFMEHIITYNEFAENPAIIDNQNLVVKIGNRYYNWTLAAPLILSLQAFQKNLPKATEEAWVKERMPKKSGRWWFWRKRADSTIKQSESTGKLEAKQSQLEEGSSSLSMESHARKVDTRDSSSDEEGKEVSAAASSMERKIQSEPHGHTSTHSYRKSLRLSSSQIASLK-LKEGPNDVMFSITTQYQGTCRCEGTIYLWNWDDKVIISDIDGTITKSDVFGQILPQFGKDWTHQGIAKLYHSVAENGYKFLYCSARAIGMADMTRGYLQWVNDGGIILPRGPLMLSPSSLFSAFHREVIEKKPEIFKIECLTDIKNLFLPNK-HPFYAAFGNRTNDVFAYKEVGVPVCRIFTVNPKGELIQEQTKGNKSSYSRLSELVDHVFP-LLSKEQSSAFSFPEFSTFCFWRQPIPEIRPEDLLL", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P32567-1", "uniprot_id": "PAH1_YEAST", "id": "P32567-1", "name": "Phosphatidic acid phosphohydrolase 1", "aln": "-------------------------------------MQYVGRALG----SVSKTWSSINPATLSGAIDVIVVEHPDGRLSCSPFHVRFGKFQILKPSQKKVQVFINEKLSNMPMKLSDSGEAYFVFEMGDQVTDVPDELLVSPVMSATSSPPQSPETSILEGGTEGEGEGENENKKKEKKVLEEPDFLDINDTGDSGSKNSETTGSL------SPTESSTTTPPDSVEERKLVEQRTKNFQQKLNKKLTEIHIPSKLDNNGDLLLDTEGYKPNKN--------MMHDTDIQLK---QLLKDEFGNDSDISSFIKEDKNGNIKIVNPYEHLTDLSPPGTPPTMATSGSVLGLDAMESGSTLNSLSSSPS-------GSDTEDETSFSKEQSSKSEKTSKKGTAGSGETEKRYIRTIRLT----NDQLKCLNLTYGENDLKFSVDHG-KAIVTSKLFVWRWDVPIVISDIDGTITKSDALG--------HVLAMIGKDWTHLGVAKLFSEISRNGYNILYLTARSAGQADSTRSYLRSIEQNGSKLPNGPVILSPDRTMAALRR---EVILKKPEVFKIACLNDIRSLYFEDSDNEVDTEEKSTPFFAGFGNRITDALSYRTVGIPSSRIFTINTEGEVHMELLELAGYRSSYIHINELVDHFFPPVSLDSVDLRTNTSMVPGSPPNRTLDNFDSEITSGRKTLFRGNQEEKFTDVNFWRDPLVDIDNLSDISNDDSDNIDEDTDVSQQSNISRNRANSVKTAKVTKAPQRNVSGSTNN-NEVLAASSDVENASDLVS----SHSSSGSTPNKSTMSKGDIGKQIYLELGSPLASPKLRYLDDMDDEDSNYNRTKSRRASSAAATSIDKEFKKLSVSKAGAPTRIVSKINVSNDVHSLGNSDTESRREQSVNETGRNQLPHNSMDDKDLDSRVSDEFDDDEFDEDEFED---", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *:***: * ::.: :..** *****.***:**.: ** .**********: :*:..:* ::: ** . :: ***.*.***:** * :: :* * .**: : .. : : .: . : . . :. . * . . :.: : :.. . . .. . * : : * .. . . .:.* .. *::: :: .**: * : . * :. : : : : . ::*. .. . .. * .: .: . * : . .. : . * . : :. * * .:* . * ..* . :*. . : . * : :*. :. *. * .. * * . : :.: ::. : . . ::.:.* ::. . : : . : * * ::.: ::. . :: : :** :: . : . .:. . . . :* ... . . : :. .: . :. .:.*. : * * * :: *: .. ::.. ..: . :*. *.: .. :*: : .. . . :. : . :* :.* .*: . . :*:. .. * :..: . . :. .*: :: : * .. : .: : :* .. :. : .*. . . *. . : :: **..: * .: *:.. * ::. . . : : : : : :* ", "identical_positions": 102, "similar_positions": 292, "identity": "10.73%" }, { "cls_id": "homologset.agr.MGI:1891342", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q99PI4-1", "uniprot_id": "LPIN3_MOUSE", "id": "Q99PI4-1", "name": "Phosphatidate phosphatase LPIN3", "aln": "-------------------------MNYVGQLAETVFGTVKELYRGLNPATLSGGIDVLVVRQRDGSFRCSPFHVRFGKLGVLRSREKVVDIEINGEPVDLHMKLGDSGEAFFVQELDSDEEDVPPRLCTSPIPWGG--LSGFPSDSQIGTASEPEGLVIT-----GRRKRRRRRKPRRREE-DAVDSSSEELEAGAESELTLLEKPTPESPSAQEA-EEPSSQPKDIHPYSDGECTPQANLSSGDLMSPKSDSELELRSLEPSPLRAESHMQWVWGRLPKVAKAERPEFSLILESMAEAICA----------LPEEPSPSSSPSEAGVDTLS--------PPVLHPGVRADTFHPAVEAHCEETAVDS--------------------------------------------------------------------------------------------PLAAPESKETK------TQNSRGAGHPPATKSWSWTTPESHTPSGHP-QVSRGKGSLKRNQHLGPSDIYLDDLPSLDSENVALYFPKSEYGMGARRWSE------PSNQKLLE-------SPNPEHIAECTLDSVDKIELSLCGGLADNRDISLEKFTQHMVSYEDLTKNPGLLDDPNLVVKINEKHYNWAVAAPMILSLQAFQKNLPESTVDKLEKEKMPRKGGRWWFSWRRRDFP---------AEEHSSQREKAATRKQQGEKTEVLSSDDDVPDSPVILEVPPLPSSTPGYVPTYKKSLRLSSDQIRCLNLNEGANDVVFSVTTQYQGTCRCKAT-----IYLWN-----WDDKVVISDIDGTITKSDALGHILPQLGKDWTHQGITSLYHKIHLNGYKFLYCSARAIGMADLTKGYLQWVSEHG-CGLPKGPILLSPSSLFSALHR----EVIEKKPEVFKVACLSDIQQLFLPQRQPFHAAFG--NRPNDVFAYRQVGLPESRIFTVNPRGELIQELIKSHKSTYQRLGEVVELLFPPVVRGPSTDLASPEYSNLSYWRKPLPYVDFEALA", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8J8YGA4-1", "uniprot_id": "A0A8J8YGA4_RAT", "id": "A0A8J8YGA4-1", "name": "phosphatidate phosphatase", "aln": "-------------------------MNYVGQLAETVFGTVKELYRGLNPATLSGGIDVLVVKQVDGSFRCSPFHVRFGKLGVLRSREKVVDIEINGEPVDLHMKLGDSGEAFFVQELDSDEEDVPPRLCTSPIPWGG--LSGFPSDSQLGTASEPEGLVLT-----GRRKRRRRRKPRRRE--DAADSSSEELEAGAESELTLLEKPMPESPSAWKE-EEPSSQPKDIYPYSDGECTPQANLSSADLMSPKSDSELELRPLEPSPLRAESHMQWAWGRLPKVAKAEHPEFSLVLESMAEAICA----------LPGEPSPSS---MAGVDTLR--------SPALQPGVREDMFHPDVEAYREETPMDS--------------------------------------------------------------------------------------------PLAAPESKETK------TQNPRGTGHPPATKSWSWTTPESHTPSGRT-EVSRGRASLKRSQHLGPSDIYLDDLPSLDSENVALYFPKSDCGMGARRWSE------PSNQKLLE-------NPSREHTAECTLDSVDRIELSLCGGLADTRDISLEKFTQHMVSYEDLTKNPGLLDDPNLVVKINEKHYNWAVAAPMILSLQAFQKNLPESTVDKLQKEKMPRKGGRWWFSWRRRDFP---------AEERSAQREKAATRKQQGEKTEVLSSDDDVPDSPVILEVPPLPSSTPGYVPTYKKSLRLSSNQIRCLNLNEGANDVVFSVTTQYQGTCRCKAT-----IYLWN-----WDDKVVISDIDGTITKSDALGHILPQLGKDWTHQGITSLYHKIHLNGYKFLYCSARAIGMAHLTKGYLQWVSEHG-CGLPKGPILLSPSSLFSALHSTHLLLVIEKKPEVFKVACLSDIQQLFLPQRQPFYAAFG--NRPNDVFAYRQVGLPESRIFTVNPRGELIQELIKNHKSTYQRLGEVVELLFPPVVRGPSTDLANPEYSNLCYWRKPLPCVDFDTLV", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9BQK8-1", "uniprot_id": "LPIN3_HUMAN", "id": "Q9BQK8-1", "name": "Phosphatidate phosphatase LPIN3", "aln": "-------------------------MNYVGQLAETVFGTVKELYRGLNPATLSGGIDVLVVKQVDGSFRCSPFHVRFGKLGVLRSREKVVDIELNGEPVDLHMKLGDSGEAFFVQELESDDEHVPPGLCTSPIPWGG--LSGFPSDSQLGTASEPEGLVMAGTASTGRRKRRRRRKPKQKEDAVATDSSPEELEAGAESELSLPEKLRPEPPGVQLE-EKSSLQPKDIYPYSDGEWPPQASLSAGELTSPKSDSELEVRTPEPSPLRAESHMQWAWGRLPKVARAERPESSVVLEGRAGATSP----------PRGGPSTPSTSVAGGVDPLG--------LPIQQTEAGAD-LQPDTEDP---TLVGP--------------------------------------------------------------------------------------------PLHTPETEESK------TQSSGDMGLPPASKSWSWATLEVPVPTGQPERVSRGKGSPKRSQHLGPSDIYLDDLPSLDSENAALYFPQSDSGLGARRWSE------PSSQKSLR-------DPNPEHEPEPTLDTVDTIALSLCGGLADSRDISLEKFNQHSVSYQDLTKNPGLLDDPNLVVKINGKHYNWAVAAPMILSLQAFQKNLPKSTMDKLEREKMPRKGGRWWFSWRRRDFL---------AEERSAQKEKTAAKEQQGEKTEVLSSDDDAPDSPVILEIPSLPPSTPPSTPTYKKSLRLSSDQIRRLNLQEGANDVVFSVTTQYQGTCRCKAT-----IYLWK-----WDDKVVISDIDGTITKSDALGHILPQLGKDWTHQGITSLYHKIQLNGYKFLYCSARAIGMADLTKGYLQWVSEGG-CSLPKGPILLSPSSLFSALHR----EVIEKKPEVFKVACLSDIQQLFLPHGQPFYAAFG--NRPNDVFAYRQVGLPESRIFTVNPRGELIQELIKNHKSTYERLGEVVELLFPPVARGPSTDLANPEYSNFCYWREPLPAVDLDTLD", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AB32TSJ5-1", "uniprot_id": "A0AB32TSJ5_DANRE", "id": "A0AB32TSJ5-1", "name": "phosphatidate phosphatase", "aln": "MAAEGRRGPAFTRHHPHHASIWSQTMNYVGQLAETVFVTVKELYRGLNPATLTGGIDVIVVRQPDGSFQCSPFHVRFGKLGVLRSKEKVVDIEINGEPVSLHMKLGDNGEAFFVEENEDFETRVPAHLCTSPIPTDVP-EASEVTESQLSCSNRRK----------KRRRKRVRSDTHLHEDDSSSSDEKESLDPDALKEESLLAASKSIYYSLSEEPYEEASGAREVHPHSDGECSLNESVYFSRPSSPKSDSELCKAQESLGP-----QMQWNWGAFPKVCPSERVESDSLTHELPSPITPSDHSHFRTIHRQTSVDIDSTDSAVTVTVVRPEPQIGTVSPVSSDEAVCSSINTQLNVKFTNTLQSPDDCFSQSWSGLENKHSQEIIAEKEIETMTSCGNTVNESNNDASLDSVAHLENCSENNIVRTITFGESNQDLKAEAELNSILLPKHQSSVEILTLRASESEEGAGLETLPTNQNADSAGVTGSQEIIVQSEDPTVLEASKSADSQDKRKVKRSHHLGPSDIYLDDLSSLDPEVAALYFPKSEAESSDLRSSHGPDPSPPSGQMSPQSQGSANADSGTEYLSDSTSDSLD-VTMSLCG-RGDISQISKEKFMEHLVKFQDFVNNPGIIEDPNLVICINSKYYNWAVAAPMILSVQAFQKTLPKSTIEQLVKDKMPKKSGRWWFSWRRKDLNNIPGNPKAGAEESQLEASASVAGPSTLKSSVELSSDEDG--SVSVRKNTELMNTAQCISQMYRKSLRLTSEQIESLNLREGANKVVFSVTTQYQGTCRCEAA-----IYLWS-----YDDKIIISDIDGTITKSDALGHILPQLGKDWTHHGIAKLYHKIHQNGYKFLYCSARAIGMADITKGYLQWVNDRG-TVLPKGPVLLAPSSLFSALHR----EVIEKKPEVFKIACLTDIRDLFSSVTQPFYAAFG--NRTNDAYAYKEVGVPETHIFTVNPKGELIREKTKGNKSSYSHLSELVDHFFPLICKHPTTSFDCPEFSHFTFWRAPLPPLDLQELI", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P32567-1", "uniprot_id": "PAH1_YEAST", "id": "P32567-1", "name": "Phosphatidic acid phosphohydrolase 1", "aln": "-------------------------MQYVG----RALGSVSKTWSSINPATLSGAIDVIVVEHPDGRLSCSPFHVRFGKFQILKPSQKKVQVFINEKLSNMPMKLSDSGEAYFVFEMGDQVTDVPDELLVSPVMSATSSPPQSPETSILEGGTEGEGE--------GENENKKKEKKVLEEPDFLDINDTGDSGSKNSETTGSLSPTESSTTTPPDSVEERKLVEQRTKNFQQKLNKKLTEIHIPSKLDNNGDLLLDTEGYKPNK----NMMHDTDIQLKQLLKDEFGNDSDISSFIKEDKNG------------NIKIVNPYEHLTDLSPPG-------TPPTMATSGSVLGLDAMESGSTLNSLSSS--------------------------------------------------------------------------------------------PSGSDTEDETS------FSKEQSSKSEKTSKKGTAGSGETEKRYIRTIRLTNDQLKCLN-LTYGENDLKFSVDHGKAIVTSKLFVWRWDVPIVISDIDGTITKSDALGHVLAMIGKDWTHLGVAKLFSEISRNGYN--ILYLTARSAGQADSTRSYLRSIEQNGSKLPNGPVILSPDRTMAALRREVILKKPEVFKIACLNDIRSLYFEDSDNEVDTE---EKSTPFFAGFGNRITD--------ALSYRTVGIPSSRIFTINTEGEVHMELLELAGYRSSYIHINELVDHFFPPVSLDSVDLRTNTSMVPGSPPNRTLDNFDSEITSGRKTLFRGNQEEKFTDVNFWRDPLVDIDNLSDISNDDSDNIDEDTDVSQQSNISRNRANSVKTAKVTKAPQRNVSGSTNNNEVLAASSDVENASDLVSSHSSSGSTPNKSTMSKGDIGKQIYLELGSPLASPKLRYLDDMDDEDSNYNRTKSRRASSAAATSIDKEFKKLSVSKAGAPTRIVSKINVSNDVHSLGNSDTESRREQSVNETGRNQLPHNSMDDKDLDSRVSDEFD--DDEFDEDEFED--", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *:*** .: :*.: : .:*****:*.***:**.: ** : **********: :*:. :* *:: :* : .: ***.*.***:** * . ** * .**: . * : ... : ....: : . .* .. . . . . : : ..: .: . :.* * . . *: : :: * : . : . : * :.. . : .. . : .* .. . ::. : : :..: . . * .*: :. . *:. : : . . .: : .: : : : : * . .. : : . : . . ..: :.* ::. . : :. : . * .:: ::. :.: ::: : .*. :: .: .: . : : :. : . * .** .:. : .. :.. .:*: : * : : :* *: **: *. ..*: .::.:: :: : * .. . . ..:. : .:. : *.. . . . :: ..: . :: : . * . :. * . :. ** :: . : :.* * : .:* .:: .. :* .: : . ..: ..: : ::: ", "identical_positions": 83, "similar_positions": 263, "identity": "8.0%" }, { "cls_id": "homologset.agr.MGI:1891343", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8BGM7-1", "uniprot_id": "AAKG3_MOUSE", "id": "Q8BGM7-1", "name": "5'-AMP-activated protein kinase subunit gamma-3", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MEPELEHTLPG----------------TLTWSHSGGPESQEMDFLEQG--------------ENS-WPSPAVATSSERTCAIRGVKASRWTRQEAVEEAEPPGLGEGAQSRPAAESTRQEAT---FPKATPLAQAVPLAEAETS------------------------------PTGWDLLLP------------------------------------DCAASAGG---------------------------------------------------------------------------------------------------------------SSTGDLELTIEFPAPEAWDCELE-----------GLGKD------------RPRPGPSPQAPLLGLSWDDELQKPGAQVYMHFMQEHTCYDAMATSSKLVIFDTTLEIKKAFFAMVANGVRAAPLWDSKKQSFVGMLTITDFILVLHRYYRSPLVQIYEIEEHKIETWREIYLQGCFKPL--VSISPNDSLFEAVYALIKNRIHRLPVLDP----VSGTVLYILTHKRLLKFLHIFGALLPRPSFLCRTIQDLGIGTFRDLAVVLETAPVLTALDIFVDRRVSALPVVNESGQVVGLYSRFDVIHLAAQQTYNHLDMSVGEALRQRTLCLEGVLSCQPHESLGEVIDRIAREQVHRLVLVDETQHLLGVVSLSDILQALVLSPAG-------------------------IDALSA---------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D4A7E4-1", "uniprot_id": "D4A7E4_RAT", "id": "D4A7E4-1", "name": "", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MEPELEHTLPGVPGSQGAAEKDSKRVATLTWSHSGGPESQEMDFLEPE--------------ENS-WPSPTVATSSERTCAIRGVKASRWTRQEAVEEAEPPGLGEGAQSGPAAESTRQKAT---FPKATPLAQAVPLADAETS------------------------------TTGWDLFLP------------------------------------DCAASAVG---------------------------------------------------------------------------------------------------------------SSTGDLELTIEFPGPEVWDCELK-----------GLEQD------------RPRPCPSPQAPLLSLSWDDELQKPGAQIYMHFMQEHTCYDAMATSSKLVIFDTTLEIKKAFFAMVANGVRAAPLWDSKKQSFVGMLTITDFILVLHRYYRSPLVQIYEIEEHKIETWREIYLQGCFKPL--VSISPNDSLFEAVYALIKNRIHRLPVLDP----VSGTVLYILTHKRLLKFLHIFGALLPRPSFLCRTIQDLGIGTFRDLAVVLETAPILTALDIFVDRRVSALPVVNESGQVVGLYSRFDVIHLAAQQTYNHLDMSVGEALRQRTLCLEGVLSCQPHESLGEVIDRIAREQVHRLVLVDETQHLLGVVSLSDILQALVLSPAG-------------------------IDALSA---------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9UGI9-1", "uniprot_id": "AAKG3_HUMAN", "id": "Q9UGI9-1", "name": "5'-AMP-activated protein kinase subunit gamma-3", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MEPGLEHALRR----------------TPSWSSLGGSEHQEMSFLEQE--------------NSSSWPSPAVTSSSERIRGKRRAKALRWTRQKSVEEGEPPGQGEGPRSRPAAESTGLEAT---FPKTTPLAQADP-AGVGTP------------------------------PTGWDCLPS------------------------------------DCTASAAG---------------------------------------------------------------------------------------------------------------SSTDDVELATEFPATEAWECELE-----------GLLEE------------RPALCLSPQAPFPKLGWDDELRKPGAQIYMRFMQEHTCYDAMATSSKLVIFDTMLEIKKAFFALVANGVRAAPLWDSKKQSFVGMLTITDFILVLHRYYRSPLVQIYEIEQHKIETWREIYLQGCFKPL--VSISPNDSLFEAVYTLIKNRIHRLPVLDP----VSGNVLHILTHKRLLKFLHIFGSLLPRPSFLYRTIQDLGIGTFRDLAVVLETAPILTALDIFVDRRVSALPVVNECGQVVGLYSRFDVIHLAAQQTYNHLDMSVGEALRQRTLCLEGVLSCQPHESLGEVIDRIAREQVHRLVLVDETQHLLGVVSLSDILQALVLSPAG-------------------------IDALGA---------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F1QK10-1", "uniprot_id": "F1QK10_DANRE", "id": "F1QK10-1", "name": "", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MLG---------------------------------------------------------------------------------------------------------------PQT--MDPLTEFP-----FMEDE-----------GLTMK------------RTGP----------------LQDPDADVYAKFFMSHCCYDAIPTSSKLVVFDTTLQVKKAFFALVANGVRAAPLWDDKLQCFVGMLTITDFINILHRYYKSPLVQIYELEEHKIETWRETYLQYSVTSL--ISIAPDSSLFEAIYSLLKNKIHRLPVIDP----ETGNVLHILTHKRILKFLHIFGSMIPKPRFLQKRIEEVEIGTFKSIATVKETETVYDALTIFVERRVSALPVVNEQGKVVALYSRFDVINLAAQKTYNHLNMTMAEAIQGRWCCIEGVLKCYPHETLETVIDRIAEAEVHRLVLVDTEDVVRGIVSLSDLLQALVLTPAG-------------------------VEALFS---------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VDD2-1", "uniprot_id": "Q9VDD2_DROME", "id": "Q9VDD2-1", "name": "", "aln": "MATNCDFIEQPVKQQPLANAPVMGVQEDKAQEPKELPDEPAKQPDGQPYQHFAGEDSFECAFESTMDDLEQGVLDGYESDSEASANDQITDSASSGSLGQLAQQQQREERLRGLPGPLHGQHIDSEMLKCMPRSNSFDFHSSSGSSSDDEDDPDDDDDDQVHHSLGLSLSGKFVKVDLYSGHQRPGYLLPPYIERRRLSQCKEEDDEDEGDRTQLGGGSSSTGESTKSEKASKAPPRPPTPQDEASKEKFKDLERLRQQFMHKIDRINTRNIEESEAPPPPPPPPPPIPATILPKALKALLHTQEPVAPPSRPSPVGPPSPAPTSSVIVAKETPVPVTPEPVSPLPLPTEPPLIIKGKFKVTLAQETPELRVEAQKLSKLNASSNAHTISFPSSFGGYSSVQGLFSQRYGSNRFPTAAPHMSKQFFEPSLVEIRTPAQSNVALNTTGLANSNHQSLTCDTNSLANKPRTPSERELDEIWIRRQDGGLSGTAAPGAPGAPLPLLQQQQQQQRPVSLGGASTMPRLLRSESSASTTSPSRQLTNSGSVSVSVSDDEQDGSLGGAGRMPGSRPSSAPAEPNAKAAKKAYKKMEKEQRRQEKEQSRREKEARKLERETARRNEREAAKLEKINRHSEKISRSTERMAMAGVGSRSGSLERRRSGEDSPVLNQSTVHGIASPNRRPTIFDVFRPRAKSDAKRQKEKHLLDPSSADSSATSSTYSVSGGTGPATSSAAGGAGGAAAAAGQGAAGGAGGLMNSMKVAMQNFSHRQHPAVTITSADGTQSTAKSKYKDGSAHPHQGSDAQYYHTVTAVRPNSSQRSPMTKVMDLFRHRSSSVVSEADKRKARAAAHQQQLAVQSAHMRRASADLEKRRASVGAAGRGLRGDGTLDPHHAAILFRDSRGLPVADPFLEKVNLSDLEEDDSQIFVKFFRFHKCYDLIPTSAKLVVFDTQLLVKKAFYALVYNGVRAAPLWDSEKQQFVGMLTITDFIKILQMYYKSPNASMEQLEEHKLDTWRSVLHN-QVMPL--VSIGPDASLYDAIKILIHSRIHRLPVIDP----ATGNVLYILTHKRILRFLFLYINELPKPAYMQKSLRELKIGTYNNIETADETTSIITALKKFVERRVSALPLVDSDGRLVDIYAKFDVINLAAEKTYNDLDVSLRKANEHRNEWFEGVQKCNLDESLYTIMERIVRAEVHRLVVVDENRKVIGIISLSDILLYLVLRPSGEGVGGSESSLRASDPVLLRKVAEVEIPATAAAATTTTPPRSPSAGSGNRSLIEDIPEEETAPARSDDADSDNNKSASEDKANNNQHDQTTTAATANGDSNNSPVEVSFADEAQEEEAADQVERSNCDDDDQPALAEIERKNASMDDDEDDGMSSAVSAASALGQSLTPAAQEMALVSE", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P12904-1", "uniprot_id": "AAKG_YEAST", "id": "P12904-1", "name": "5'-AMP-activated protein kinase subunit gamma", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MKPTQDSQEKVSIEQQLA-----------------------------------------------------VESIRKFLNSKTSYDVLPVSYRLIVLDTSLLVKKSLNVLLQNSIVSAPLWDSKTSRFAGLLTTTDFINVIQYYFSNP-DKFELVDKLQLDGLKDIERALGVDQLDTASIHPSRPLFEACLKMLESRSGRIPLIDQDEETHREIVVSVLTQYRILKFVALN---CRETHFLKIPIGDLNIITQDNMKSCQMTTPVIDVIQMLTQGRVSSVPIIDENGYLINVYEAYDVLGLIKGGIYNDLSLSVGEALMRRSDDFEGVYTCTKNDKLSTIMDNIRKARVHRFFVVDDVGRLVGVLTLSDILKYILLGSN-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . : : : :*: : .** :..* :*:::** * :**:: .:: *.: :*****.: . *.*:** **** ::: *: .* .: ::: ::: :. . * ** *. .*::* ::..: *:*::* *: :**: *:*:*: : .. :: : :: * * .: * .: .: :.: ***::*:::. * :: :* :**: * **.*.::: :* * :*** .* .:.* :::.* . .***:.:** : *:::***:* ::* . ", "identical_positions": 75, "similar_positions": 119, "identity": "5.33%" }, { "cls_id": "homologset.agr.MGI:1891344", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "F1LRA5-1", "uniprot_id": "F1LRA5_RAT", "id": "F1LRA5-1", "name": "", "aln": "MGWKILPICLSMLLPVFLIQQVSSQDISSCAGRCGEGYSRDATCNCDYNCQHYMECCPDFKRVCTTELSCKGRCFESFARGRECDCDSQCKQYGKCCADYNSFCEEVHNPTSPPP-KTAPPPPGASRTIKSTTKRSPKSP-KKKTKKVVESEEITEEHSVSENQESSSSSSSSSS--TIRKIKSSKN-SANRELQKNPKVKDNKKNTPKKKPNPEPPVVDEAGSGLDNGEPKLTPPP-DPP-TPHNKVTASPKTTAAKPVTPKPSLAPNSETSKEASSTSNKETTVETKETTETNKQSSASKKEKTTSAKETRSAENTSAKDVEPTS-----------TTPKNSAPTTTKKP-VTTTKEPVPTTTKGPEPTSKEPAPTTPKEPELTIPKEPAPTTKKPAPTTPKEPAPTTPKEPEPTTPKESA-------PTTPKEPAPTTPKEPAPTTPKEPAPTTPKEPAPTTPKEPAPTTKKPEPTTPKEPAPTTPKEPAPTTPKEPAPNTPKEPAPTTPKEPAPTTPKEPE----------------------STTPKEPAPTTPKEPAPTTPKEPAPTTPKEPAPTTPKEPAPTTPKEPAPTTPKEPAPTTPKEPAPTTPKEPVPTTPK--------------------------------EPASTTPKEPAPTTPKEPAPTTPKEPAPTTPKEPAPTTPKEPAPTTPKEPALTTPK-EPAPTPKEPEPTTPKEPA-----------------------------PTTPKEPAPTTPKEPAPTTKK------PELTIPKEPVPTTPKEPAPTTPKEPAPTTTKKPELSTPKEPTSTNPKEPEPTLPKEPELTLPEEPEPSNPET---------------SDELIAELAEAPTPKALENNPKEPTVPT-ETPEVSKPEMTTAKEKTTEKDTTQTTTTVTPKTTTETTIIPEETTEPRASTTTRITSTAQDTTSPQMTTLKATTLAAKVTAPTEEIQSKPEETTLTTPALEGSDASKTTLKPQKPTKAPKKPASTKKPTKAPKKPTSTKKPK-TPKGRKPKTTPSPLKTSTMS-EQNTTP--LEVMLPTTTVPKQTPNSETAEVNPAHEDADGGEGEKP-LIPRPPVLSPTAVPGTDLLVERLNPGINIHPMFSDETNICNGKPVDGLTTLRNGTLVAFRGHYFWMLN-PFRPPSPPRRITEVWGIPSPIDTVFTRCNCEGKTFFFKDSQYWRFTNDVMDAGYPKLIVKGFGGLTGKIVAALSIAKYKDRPESVYFFKRGGNIQQYTYKQEPVRKCTGRQPAINYSVYGQAAQVRRRRFERAVGPFQTHTFRIHYSVPIKASYQDKGFLHNEVKVSTLWRGFPNVVTSAITLPNIRKPDGYDYYAFSKDQYYNIDVPTR---TARAITTRSGQTLSRVWYNCP-----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9JM99-1", "uniprot_id": "PRG4_MOUSE", "id": "Q9JM99-1", "name": "Proteoglycan 4", "aln": "MGWKILPVCLSLLLPVVLIQQVSSQDLSSCAGRCGEGYSRDATCNCDYNCQHYMECCPDFKRVCSPELSCKGRCFESFARGRECDCDSQCKQYGKCCADYDSFCEEVHNSTSPSS-KTAPTPAGASDTIKSTTKRSPKSP-TTRTIKVVESEELTEEHSDSENQESSSSSSSSSS--TIRKIKSSKN-SANRELQKNPNVKDNKKNTPKKKPNPEPPAVDEAGSGLDNGEFKLTPPPPDPPTTPHSKVATSPKTTAAKPVTPKPSLAPNSETSKEASLASNKETTVETKETTATNKQSSASKK-KTTSVKETRSAEKTSDKDVEPTS-----------TTPKNSAPTTTKKP-VTTTKE------------SK--FLPLPQEPEPTTAKEPPPTTKKPEPTTRKEPEPTTPKEPEPTTPKE-------------------------------PEPTTPKEPEPTTPKEPPPTTKKPEPTTPKEPGPTTPKEPEPTTTKEPEPTTTKEPESTTRKEPEPTTPKEPE----------------------PTTPKEPEPTTLKEPEPTTPKEPEPTTPKEPEPTTPKEPEPTTPKEPEPTTPKEPEPTTPKEPEPTTPKEPEPTTPK--------------------------------EPEPTTPKKPEPTTPKEPVPTTPKEPEPTTPKEPEPTTPKEPEPTTRKE----------------PEPTTPKEPE-----------------------------PTTPKEPEPTTPKKPEPTT------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------TSPKTTTLKATTLAPKVTAPAEEIQNKPEE---TTPASEDSDDSKTTLKPQKPTKAPKP---TKKPTKAPKKPTSTKKPK-TPKTRKPKTTPSPLKTTSATPELNTTP--LEVMLPTTTIPKQTPNPETAEVNPDHEDADGGEGEKP-LIPGPPVLFPTAIPGTDLLAGRLNQGININPMLSDETNLCNGKPVDGLTTLRNGTLVAFRGHYFWMLN-PFRPPSPPRRITEVWGIPSPIDTVFTRCNCEGKTFFFKDSQYWRFTNDVVDPGYPKQIVKGFGGLTGKIVAALSIAKYKDRPESVYFFKRGGNIQQYTYKQEPMKKCTGRRPAINYSVYGEAAQVRRRRFERAVGPFQTHTFRIHYSVPMRVSYQDKGFLHNEVKVSTMWRGFPNVVTSAITLPNIRKPDGYDYYAFSKDQYYNIDVPTR---TARAITTRSGQTLSKIWYNCP-----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q92954-1", "uniprot_id": "PRG4_HUMAN", "id": "Q92954-1", "name": "Proteoglycan 4", "aln": "MAWKTLPIYLLLLLSVFVIQQVSSQDLSSCAGRCGEGYSRDATCNCDYNCQHYMECCPDFKRVCTAELSCKGRCFESFERGRECDCDAQCKKYDKCCPDYESFCAEVHNPTSPPSSKKAPPPSGASQTIKSTTKRSPKPPNKKKTKKVIESEEITEEHSVSENQESSSSSSSSSSSSTIRKIKSSKNSAANRELQKKLKVKDNKKNRTKKKPTPKPPVVDEAGSGLDNGDFKVTTPD--TSTTQHNKVSTSPKITTAKPINPRPSLPPNSDTSKETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTSDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPKALENSPKEPGVPTTKTPAATKPEMTTTAKDKTTERDLRTTPETTTAAPKMTKETATTTEKTTESKITATTTQVTSTTTQDTTPFKITTLKTTTLAPKVTTTKKTIT---TTEIMNKPEETAKPKDRATNSKATTP--KPQKPTKAPKKPTSTKKPKTMPRVRKPKTTPTPRKMTSTMPELNPTSRIAEAMLQTTTRPNQTPNSKLVEVNPKSEDAGGAEGETPHMLLRPHVFMPEVTPDMDYLPRVPNQGIIINPMLSDETNICNGKPVDGLTTLRNGTLVAFRGHYFWMLS-PFSPPSPARRITEVWGIPSPIDTVFTRCNCEGKTFFFKDSQYWRFTNDIKDAGYPKPIFKGFGGLTGQIVAALSTAKYKNWPESVYFFKRGGSIQQYIYKQEPVQKCPGRRPALNYPVYGETTQVRRRRFERAIGPSQTHTIRIQYS-PARLAYQDKGVLHNEVKVSILWRGLPNVVTSAISLPNIRKPDGYDYYAFSKDQYYNIDVPSR---TARAITTRSGQTLSKVWYNCP-----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1PHS8-1", "uniprot_id": "A0A8M1PHS8_DANRE", "id": "A0A8M1PHS8-1", "name": "", "aln": "---MTGLTVLWSLLALLCTVLPSSAAQGSCVGRCGEQFSRGHICNCDYNCFVHGECCKDFEDICTASESCRGRCGEPFRRGRQCECDSGCVLHNSCCPDYSTHCDAFSHLQAPRSS---KPNKPADYTEECIA--------------------------------------------ACLAAQQNPDVMRYGSGLNNLM---------------TPSASPFLAGDVSQDG----------PYT------------------------------------------------------------------------------------------------------------------------------------------------------------PLSASD---------------------------------------------------IPGLSSSPSEFHLAES-------------------------------------------------------------------------------------------------------DAAAPLQPAG----------------------------------------------------------------------------ASSENPQAVPVQVSLSISGQADRPSSSSGRPSIP----------------------------------------------------------------------ADIAQAPAD------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SSPAGPG--------------------------------------------------------------------------------------------------------------LNLCSGVVIDGMAALFNGSIIVFRGHFFWLLNPKTRRAGPARRITEELGVPSPIDTAFTRCNCQGKTYIIKGDSYWSFENGVLESGYPRSVSQDFGGLSGDITAALPVPATRKRPESVYFFKKGGKVQKLSFPPGSGPNCSGK-RSKNADKP------------------------------SKNGKQAEIQLSGEINIKLKMKGFPSAVSSAVSMPNPRKSDGFDYLVFSWPKVLNVKISGDLPALTAPASHSSQQNDITKWLHCA-----", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0AC58I2W8-1", "uniprot_id": "A0AC58I2W8_DANRE", "id": "A0AC58I2W8-1", "name": "", "aln": "------MATYLSVLLLFVWVSTSSSNPRSCGGRCGEGYYRGSFCQCDYDCLGLNECCADFQDLCTSKDSCKGRCGEPFNRGNPCHCDIDCVSYNQCCPDYESMCLIEAYISVTVTDSALKPRNTASAAQRIAN--------------------------------------------LCLNIKNKKSTESSNEEMTNLEGTGDEFTVPEYETEPTPSEGRDVPAEILPEG----------PYTGSDIEEKQKENSTFHPENETSSPAPSTPTADVSSIFPADENHIDFTTQQPSEELTASSTLQPQENSSIALTEGPTSVTPVDDSP---------------------------------------------------------EEDPKKQTITVDPTSPVPAEDP-------------------------------------------------TSPGLAEDPTSPGPAEDPISPVPAEDPTSPGPAEDPISPVPAEDPTSPVPAEDPISPVPAEDPTSPVPAE-----------------------------------DPTSTVAPEDPNNQTPAENPTSPAATADPTDQNPAEDPRNPAPAEDSRKPAPTEDPTSMAPTEG---------------------------------STSAAPTENLTTAPTEGATPVPRKTPAPMKPTKKPTQPSKE---------------------------------------------------------------NIDKSEVKESPKDPVVISPI--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------RVTEKPLKPSSDLNGR--------------------------------------------------------------------------------------------TDILDYQSDDYDSNLCSGRPVSGLTTLRNGTIVVFRGHYFWTLD-KQRNPDPPQLITQVWGIPSPIDTVYTRCNCQGKTYFFKGKNYWRFENGAMDPGFPKPISEGFG-QIGHITAALSIPEYRSRKESVIFFKRGGMAQKYTYQVT--PNCGRRPKIPVITVR------------------------------MRTRRQTAAALGQVINISRTWRGFPTMVTSSVSVPS-RVKEGYKYYVFSQRNYYSMKMERDKPVILKPVTGP-KENPATSFFKCKDTQKI", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :* :. ** ** ***** : *. *:***:* *** **: :*:.. **:*** *.* **. *.** * :..**.**.: * . . . *. : . :.. . . .: *. . : . * * . .: * . .: . * * :. : :.* . :. . *: * :* . . * * *:*.* :.*:::* **:::.****:** *. ..*.: **: *:******.:*****:***:::*...** * *. :.*:*: : :.** *.*.***. . :. *** ***:** *: : :* : : * * :::. :*:*. *:*::::*. * :*:.* .** : .:.: . : :. : :* ", "identical_positions": 122, "similar_positions": 135, "identity": "8.59%" }, { "cls_id": "homologset.agr.MGI:1891346", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9EST9-1", "uniprot_id": "FGF20_RAT", "id": "Q9EST9-1", "name": "Fibroblast growth factor 20", "aln": "MAPLTEVGAFLGGLEGLGQQVGSHFLLPPAGERPPLLGERRGALERGARGGPGSVELAHLHGILRRRQLYCRTGFHLQILPDGSVQGTRQDHSLFGILEFISVAVGLVSIRGVDSGLYLGMNGKGELYGSEKLTSECIFREQFEENWYNTYSSNIYKHGDTGRRYFVALNKDGTPRDGARSKRHQKFTHFLPRPVDPERVPELYKDLLVYTG", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9ESL9-1", "uniprot_id": "FGF20_MOUSE", "id": "Q9ESL9-1", "name": "Fibroblast growth factor 20", "aln": "MAPLTEVGAFLGGLEGLSQQVGSHFLLPPAGERPPLLGERRGALERGARGGPGSVELAHLHGILRRRQLYCRTGFHLQILPDGTVQGTRQDHSLFGILEFISVAVGLVSIRGVDSGLYLGMNDKGELYGSEKLTSECIFREQFEENWYNTYSSNIYKHGDTGRRYFVALNKDGTPRDGARSKRHQKFTHFLPRPVDPERVPELYKDLLMYT-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9NP95-1", "uniprot_id": "FGF20_HUMAN", "id": "Q9NP95-1", "name": "Fibroblast growth factor 20", "aln": "MAPLAEVGGFLGGLEGLGQQVGSHFLLPPAGERPPLLGERRSAAERSARGGPGAAQLAHLHGILRRRQLYCRTGFHLQILPDGSVQGTRQDHSLFGILEFISVAVGLVSIRGVDSGLYLGMNDKGELYGSEKLTSECIFREQFEENWYNTYSSNIYKHGDTGRRYFVALNKDGTPRDGARSKRHQKFTHFLPRPVDPERVPELYKDLLMYT-", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "****:***.********.***********************.* **.******:.:***************************:**************************************.*************************************************************************************:** ", "identical_positions": 199, "similar_positions": 11, "identity": "93.87%" }, { "cls_id": "homologset.agr.MGI:1891351", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I5ZQG2-1", "uniprot_id": "A0A8I5ZQG2_RAT", "id": "A0A8I5ZQG2-1", "name": "Testican-2", "aln": "-MRAPGSGRLALPLLLLAVVALAEGDAKGLK------------------EGETPGNFMEDEQWLSSIS-----------------------------------------------QYSGKIKHWNRFRDRKLDDYIKSWEDNQQGDEALDTTKDPCQKVKCSRHKVCVAQGYQRAMCIS--------------------RKKLEHRIKQPSL------KLHGGKDSICKPCHMAQLASVCGSDGHTYSSVCKLEQQACLSNKHLAVRCEGPCPCPTEQ-----------------------------------------------------------------------------------------------------------------------------------------STASTTDSKSETCTGQDLADLGDRLRDWFQLLRENSKQNGSASSSSSPAG-LDKSLGASCKDSIGWMFSKLDTSGDLFLDQTELAAINLDKYEVCIRPFFNSCDTYKDGRVSTAEWCFCFWREKPPCLAELERTQIQEAAKKKPGIFIPSCDEDGYYRKMQCDQSSGDCWCVDQLGLELTGTRMHGNPDCDDIVGFSGDFGSGVGWEDEEEKETEEAGEEAEEEEGEAGEADDGGYIW", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9ER58-1", "uniprot_id": "TICN2_MOUSE", "id": "Q9ER58-1", "name": "Testican-2", "aln": "-MRAPGSGRLALPLLLLAVVALAEGDAKGLK------------------EGETPGNFMEDEQWLSSIS-----------------------------------------------QYSGKIKHWNRFRDEVEDDYIKSWEDNQQGDEALDTTKDPCQKVKCSRHKVCVAQGYQRAMCIS--------------------RKKLEHRIKQPSL------KLHGGKDSVCKPCHMAQLASVCGSDGHTYSSVCKLEQQACLSSKQLAVRCEGPCPCPTEQ-----------------------------------------------------------------------------------------------------------------------------------------STASTTDSKSETCTGQDLADLGDRLRDWFQLLRENSKQNGSANSATNPAG-LDKSLGASCKDSIGWMFSKLDTSGDLFLDQTELAAINLDKYEVCIRPFFNSCDTYKDGRVSTAEWCFCFWREKPPCLAELERTQIQEAAKKKPGVFIPSCDEDGYYRKMQCDQSRGDCWCVDQLGLELTGTRMHGTPDCDDIVGFSGDFGSGVGWEDEEEKETEEAGEEAEEEEGEAGEADDGGYIW", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q92563-1", "uniprot_id": "TICN2_HUMAN", "id": "Q92563-1", "name": "Testican-2", "aln": "-MRAPGCGRLVLPLLLLAAAALAEGDAKGLK------------------EGETPGNFMEDEQWLSSIS-----------------------------------------------QYSGKIKHWNRFRDEVEDDYIKSWEDNQQGDEALDTTKDPCQKVKCSRHKVCIAQGYQRAMCIS--------------------RKKLEHRIKQPTV------KLHGNKDSICKPCHMAQLASVCGSDGHTYSSVCKLEQQACLSSKQLAVRCEGPCPCPTEQ-----------------------------------------------------------------------------------------------------------------------------------------AATSTADGKPETCTGQDLADLGDRLRDWFQLLHENSKQNGSASSVAGPASGLDKSLGASCKDSIGWMFSKLDTSADLFLDQTELAAINLDKYEVCIRPFFNSCDTYKDGRVSTAEWCFCFWREKPPCLAELERIQIQEAAKKKPGIFIPSCDEDGYYRKMQCDQSSGDCWCVDQLGLELTGTRTHGSPDCDDIVGFSGDFGSGVGWEDEEEKETEEAGEEAEEEEGEAGEADDGGYIW", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A2R8Q8S3-1", "uniprot_id": "A0A2R8Q8S3_DANRE", "id": "A0A2R8Q8S3-1", "name": "Testican-2", "aln": "MVWMNNPGCVLVPLLMLVRVAMQV-DVKSGK------------------EAEKTGNFMEDEQWLSTIS-----------------------------------------------QYSRKIKHWNRFRD---DDYIRSWDENQGSNENVDTTKDPCQKVKCSRHKVCVAQGYQRAVCVN--------------------RKKLEHRLKQQVI------RQQ--QESNCKPCPVSSSGPVCGSDGHNYASQCKLEQQACLAGKELKVRCPGLCPCTATT-----------------------------------------------------------------------------------------------------------------------------------------APATDVDGKHESCTGQDLADLGDRLRDWFQLLQGNGKQNSTGSPAASSASIVDRTLVATCKDSIGWMFSKLDTNSDLYLDQAELAAINLDKYEVCIRPFFNSCDSYRDGKVSTAEWCLCFWREKPPCLAELERIQLQEGAKKKSDTYIPSCDEDGFYRRLQCDKSRGECWCVDQHGGELMGSRIHGNPDCDEVVTYSGDFGSGLGWEDEEEKEAEENGEEAEEEEGEVGEVDDGGYIW", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VCR3-1", "uniprot_id": "COW_DROME", "id": "Q9VCR3-1", "name": "Proteoglycan Cow", "aln": "MKHSPLIASACLALVLMSSSLIGSTEARNKKKYVGETGGDFEFIDEINKNTQSNKNLGEHKRWIHDPSSDLCRPLNCKKREICLLEDEFSAVCVSKKELHKNRDEIITKAKYLEEEAKRRVNQQDNQDSQDAEDINNDDEDNSSDGGSSNSSPTGTNNAQASVQGNEETDDEDKSLSLGDDDESKEDDVFYENSIAAGDKQQQQQQLSQPAAGPSVIQQDDDEELDNCKPCPVAKPTFLCGADNRTYSSLCRLDYHNCIHSTSIRIACKGFCPCKEIVDGKRLQRISGYNNKYNKKISLDQQQQQQQQQQQQQQQQQAYKDSNNNNIMMNSGNIMGGNNNDFNTIMNDKEDNNRHNNHINAQYTFTPEEIKYDNKHYKYLKYTAYKKDSKYQEDKHKMRNYNEVVEKQQQKFNKNSNLNAYPSKSAECKPQQLTAIGNRLLDWFSVIMADSKKRRQHSQKS------KAHFPPACKTEAKWMFGHLDLNNDGQLSLQEMYDLEHDQNERCIKPFIDTCDLDTDSSINTREWCRCFEKTDRPCAAVRRRIAGDFAG-----AYAPDCDIQGFYKPTQCHNSVGVCWCVDKHGVEFANTRTRGKPNCESVVNNAASLTS------------DDEDEGADDEDSAEGSADQMLVF-", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . :.*::: : :.:. * : :. *: *.::*: * : . :::: :. . :* .. ::*. .. ::: ::.:.* : ::. ::::.:. ::: ::::.* : . : . **** ::. :**:*.:.*:* *:*: : *: .. : : * * *** : . .* *. *:*: :*:** ***.:: :.*:. . : . : .:** . ***.:** . * *. *: :: *: * **:**:::** *. :.* *** ** : . ** * .* : .. : *.** :*:*: **.:* * *****: * *: .:* :*.*:*:.:* :..: * :: .* *::*:. *..*: : ", "identical_positions": 94, "similar_positions": 159, "identity": "14.4%" }, { "cls_id": "homologset.agr.MGI:1891352", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "E9Q6J6-1", "uniprot_id": "E9Q6J6_MOUSE", "id": "E9Q6J6-1", "name": "", "aln": "MEVSSELLLSNGCTSRQRVLLTASLFTCWLLSTTAKVTIHS-PLQVVEGQNVFLRVDNLPEDLLAFAWYRGLRNWRVAIALHLVEYNASMTG----PEHSDREILHSNGSLWIQNVTQEDTGYYTLQTISKHGKLVSNTSTFLQVYSALFTCGRPTSPAKLTIESVPPRVAEGGSVLLLVHNLPEYSQLFSWYKGLTLFNEVEIAEYKIAKNLSDP---GPAHSGREIVFSNGSLLLQNVTWKDTGFYTLQTVNGFREMELAHIYLRVDTPCCDPPDSARLRIDPVTCHAAEGGSVLLQVHNLPEDVQTFSWYKGVDSTPYFRIVEYSKAMKSIFSGYAHSRRETGYTNGSLLLQDVTEKDTGFYTLLTIDSHVKVETVHAQVNVHKLVTQPVVRVTDSTVRVQSSVVFTCFSDNTGVSIRWLFNNQSLQLTERMTLSPSKCQLRIHTVRKEDA--------------------------------GEYQCEAFN-------------PVSSKTSLPVSLAVMNE---------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q3KPI0-1", "uniprot_id": "CEA21_HUMAN", "id": "Q3KPI0-1", "name": "Cell adhesion molecule CEACAM21", "aln": "MGPPSACPHR-ECIPWQGLLLTASLLTFWNAPTTAWLFIASAPFEVAEGENVHLSVVYLPENLYSYGWYK----------------------------------------------------------------------------------GKTVEPNQL------------------------------------------IAAYVIDTHVRTP---GPAYSGRETISPSGDLHFQNVTLEDTGYYNLQVTYRNSQIEQASHHLRVYESVAQPS------IQASSTTVTEKGSVVLTCHTN----------------------NTGTSFQWIFN----NQR---------LQVTKRMKLSWFNHVLTIDPIRQEDAGEYQCEVSNPVSS--NRSDPLKLTVKS-------DDNT---LGILIG----VLVGSLLVAALVCFLLLRKTGRASD--------------------------------QSDFREQQP-------------PASTPGHGPSDSSIS-----------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AC58IGG2-1", "uniprot_id": "A0AC58IGG2_DANRE", "id": "A0AC58IGG2-1", "name": "", "aln": "----------------MKVLFSLFLLLFLTLHENGVSGVGKDDVSVSRGDSVTLHTGVKTNQQYIIVWLYEGIRIAVIRGDLSYICTDVQCNNGTERFRDRLKLDHLTGSLTVMNTRLRDAGEYQLLISSSKSINEMIFRVVVKDVYWVDEDDNDEESVSVIE---------GDSVTLHTGVKTDQQDRIVWFNEGSRVAVISGDLNVICTDVQCDNSTTRFKNRLNLDHQTGSLTIMNSRNTDAGEYQLLIFSSFRLSKKIFRVVVHDVHWVQEVK--------VEVSVTDGYSVTLNTDTTTKQLHKIKWYFN-----NICVAQIRGDLSYICTDVQCDEGA--------ERFGDRLKLDHQTGSLTIMNIRNRDRGEYKLEIISNRGS---RRKIFRVLVDDSGPFSAAVPRLYEIVAIAAA----VLLLAAAVSGVICCYKSKANGKNSR----------------RQRSDQAKG--------VEDCPDQNDTLLMK-------TISNSSTNQTEAAIETPT--------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0AB14YBK9-1", "uniprot_id": "A0AB14YBK9_DANRE", "id": "A0AB14YBK9-1", "name": "", "aln": "----------------MRVFI---WILWSVIFISGVSDAAADEVSVMEGESATLNAGIVKTQKDRIRWYFNGSRIAELNGDQVKICVDDVCP---DRFRGRLQLDNTSGSLIVTNTRKTDSGLYQLQINSRRTEKKFILSVQG-----ALGADTPESSVSVME---------GDSVTLCTGVQTNQSNRIKWYFYTDRIAEIIGYQHKICTDDTCP---QRFRDRLKLDSQTGSLTIMKVSTEDSGLYTFLHRG----REKIFRVVILALKNLKQK------------SATEGESITLDTPIKTTPNDVLKWYFG-----EILLAELTGGASQICEDAQCKDG-----------FRDRLKVNHSSGSLTIMNSSKADSGEYTLLINSSSFY---INGSFTVSVASVLGLSLSTG-----IGICAG----VLLVLLTVGATAFYFTIKMVKKRSKDKVKPFTLPCDNRPRDQGKSKQVNGNGMKQINQIDETDFQPTNFATESFHVEEETRSTTSSNQTSNNQEHIPFIDEEPEDEYKPGIPVIQPEKGVILE", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ::: : .. ..* .*:.. * . : * . .. .: * .. . : .*.* : : *:* * : : : . .:: *: * : . * . * *** : : . : . : * . : * :. : : . . *. . ", "identical_positions": 20, "similar_positions": 55, "identity": "3.62%" }, { "cls_id": "homologset.agr.MGI:1891354", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P40198-1", "uniprot_id": "CEAM3_HUMAN", "id": "P40198-1", "name": "Cell adhesion molecule CEACAM3", "aln": "---------------------------------------MGPPSASPHRECIPWQGLLLTASLLNFWNP-------------------------------PTTAKLTIESMP--------------------------------------------------LSVAEGKEVLLLVHNLPQHLFGYSWYK--GERVDGNSLIVGYVIGTQQATPGAAYSGRETIYTN-ASLLIQNVTQNDIGFYTLQVIK---------------------------------SDLVNEEATGQFHVYQENAPGLPVGAVAG----IVTGVLVGVALVAALVCFLLLAKTGRTSIQRDLKEQQP--QALAPGRGPS-HSSAFSMSPLSTAQAPLPNPR------TAASIYEELLKHDTNIYCRMDHKAEVAS---------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "O75871-1", "uniprot_id": "CEAM4_HUMAN", "id": "O75871-1", "name": "Cell adhesion molecule CEACAM4", "aln": "---------------------------------------MGPPSAAPRGGHRPWQGLLITASLLTFWHP-------------------------------PTTVQFTIEALP--------------------------------------------------SSAAEGKDVLLLACNISETIQAYYWHK--GKTAEGSPLIAGYITDIQANIPGAAYSGRETVYPN-GSLLFQNITLEDAGSYTLRTIN---------------------------------ASYDSDQATGQLHVHQNNVPGLPVGAVAG----IVTGVLVGVALVAALVCFLLLSRTGRASIQRDLREQPP--PASTPGHGPS-HRSTFS--------APLPSPR------TATPIYEELLYSDANIYCQIDHKADVVS---------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AC58IGG2-1", "uniprot_id": "A0AC58IGG2_DANRE", "id": "A0AC58IGG2-1", "name": "", "aln": "---------------MKVLFSLFLLLFLTLHENGVSGVGKDDVSVSRGDSVTLHTGVKTNQQYIIVWLYEGIRIAVIRGDLSYICTDVQCNNGT-----ERFRDRLKLDHLTGSLTVMNTRLRDAGEYQLLISSSKSINEMIFRVVVKDVYWVDEDDNDEESVSVIEGDSVTLHTGVKTDQQDRIVWFNEGSRVAVISGDLNVICTDVQCDNSTTRFKNRLNLDHQTGSLTIMNSRNTDAGEYQLLIFSSFRLSKKIFRVVVHDVHWVQEVKVEVSVTDGYSVTLNTDTTTKQLHKIKWYFNNICVAQIRGDLSYICTDVQCDEGAERFGDRLKLDHQTGSLTIMNIRNRDRGEYKLEIISNRGS-RRKIFRVLVDDSGPFSAAVPRLYEIVAIAAAVLLLAAAVSGVICCYKSKANGKNSR----------------RQRSDQAKG--------VEDCPDQNDTLLMK-------TISNSSTNQTEAAIETPT--------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0AB14YBK9-1", "uniprot_id": "A0AB14YBK9_DANRE", "id": "A0AB14YBK9-1", "name": "", "aln": "---------------MRVFI---WILWSVIFISGVSDAAADEVSVMEGESATLNAGIVKTQKDRIRWYFNGSRIAELNGDQVKICVDDVCP--------DRFRGRLQLDNTSGSLIVTNTRKTDSGLYQLQINSRRTEKKFILSVQG-----ALGADTPESSVSVMEGDSVTLCTGVQTNQSNRIKWYFYTDRIAEIIGYQHKICTDDTCP---QRFRDRLKLDSQTGSLTIMKVSTEDSGLYTFLHRG----REKIFRVVILALKNLKQK----SATEGESITLDTPIKTTPNDVLKWYFGEILLAELTGGASQICEDAQCKDG---FRDRLKVNHSSGSLTIMNSSKADSGEYTLLINSSSFY-INGSFTVSVASVLGLSLSTG-----IGICAGVLLVLLTVGATAFYFTIKMVKKRSKDKVKPFTLPCDNRPRDQGKSKQVNGNGMKQINQIDETDFQPTNFATESFHVEEETRSTTSSNQTSNNQEHIPFIDEEPEDEYKPGIPVIQPEKGVILE", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q810J1-1", "uniprot_id": "PSG22_MOUSE", "id": "Q810J1-1", "name": "Pregnancy-specific glycoprotein 22", "aln": "MEVSSELLSNGWTSWQRVLLTASLLTCWLLPITAGVTIESVPPKLVEGENVLLRVDNLPENLRVFVWYRGVTDMSLGIALYSLDYSTSVTGPKHSGRETLYRNGSLWIQNVTREDTGYYTLQTISKNGKVVSNTSIFLQVNSSLFICGRPSPPALLTIESVPASVAEGGSVLLLVHSLPDNLQSLLWYK--GLTVFNKVEIARHRTVKNSSEMGPAYSGREIVYSN-GSLLLQNVTWEDTGFYTLQIVN--------------------RYWKMELAHIYLQVDTSLSSCCDDFNSVQLRINPVPPHAAEG------ERVLLQVHNLPEDVQTFLWYKGVYSTQSFKITEYSIVTESLINGYAHSGREILFINGSLLLQDVTEKDSGFYTLVTIDSNVKVETAHVQVNVNKLVTQPVMRVTDSTVRIQGSVVFTCFSDNTGVSIRWLFNNQNLQLTERMTLSPSKCQLRIHTVRKEDAGEYQCEAFNPVSSKTSLPVRLTVMNE----------------", "tax_id": 10090, "tax_name": "Mouse" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . . * : :: . *. ** .* * . .: *. . . : .* : : .** : : * * * : . : : * . : : . * . : : : : ", "identical_positions": 15, "similar_positions": 34, "identity": "2.88%" }, { "cls_id": "homologset.agr.MGI:1891366", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I6ATT3-1", "uniprot_id": "A0A8I6ATT3_RAT", "id": "A0A8I6ATT3-1", "name": "Metal transporter", "aln": "MAAAAAAAAALGVRLRDCCSRGAVLLLFFSLSPRPPAAAAWLLGLRPEDTAGGRVSLEGGTLRAAEGTSFLLRVYFQPGPAVPAAPVPAPSLAPGENGTGDWAPRLVFIEEPPGAGSAAPSAVPTRPPGPQRCREQSDWASDVEVLGPLRPGGVAGSALVQVRVRELRKGEAERGGAGGGGKLFSLCAWDGRAWHHHGAAGGFLLRVRPRLYGPGGDLLPPAWLRALGALLLLALSALFSGLRLSLLSLDPVELRVLRNSGSAAEQEQARRVQAVRGRG-THLLCTLLLGQAGANAALAGWLYASLPPGVGDPGEDSGEAGVHFPWLPALVCTGAVFLGAEICPYSVCSRHGLAIASHSVCLTRLLMAAAFPVCYPLGRLLDWALRQEISTFYTRE--KLLETLRAADPYSDLVKEELNIIQGALELRTKVVEEVLTPLGDCFMLRSDAVLDFATVSEILRSGYTRIPVYEGDQRHNIVDILFVKDLAFVDPDDCTPLLTVTRFYNRPLHCVFNDTRLDTVLEEFKKGKS-HLAIVQRVNNEGEGDPFYEVMGIVTLEDIIEEIIKSEILDETDLYTDNRKKQRVPHRERRRHDFSLFKLSDSEIRVKISPQLLLATHRFMATEVEPFKSLYLSEKILLRLLKHPNVIQELKFDERNKKAPEHYLYQRSRPVDYFVLLLQGKVEVEVG--KEGLRFENGAFTYYGVPAIMTSACSDNDVRKVGSLAGSSVFLNRSPSRCSGLNRSESPNRERSDFGGSNTQLCS--NNLYTPDYSVHILSDVQFVKITRQQYQNALTACHMDSSPQSPDMEAFTDGDSTKAPTTRGTPQTPKDDPVLTLLSNRTSLPCSRSDGLRSPGEVVYLRMEEMAFPQEEMPNFEEHKAQQVSLSPVTVPTAAASETECCNIHLDPEASPCSSDSEETMGKKLLRTLSGRKRKKSADGERASEENSNLTPLIT", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q0GA42-1", "uniprot_id": "CNNM1_MOUSE", "id": "Q0GA42-1", "name": "Metal transporter CNNM1", "aln": "MAAAAAAAAALGVRLRDCCSRGAVLLLFFSLSPRPPAAAAWLLGLRPEDTAGGRVSLEGGTLRAAEGTSFLLRVYFQPGPPVPAAPVPAPSLAPGENGTGDWAPRLVFIEEPPGAGGAAPSAVPTRPPGPQRCREQSDWASDVEVLGPLRPGGVAGSALVQVRVRELRKGEAERGGAGGGGKLFSLCAWDGRAWHHHGAAGGFLLRVRPRLYGPGGDLLPPAWLRALGALLLLALSALFSGLRLSLLSLDPVELRVLRNSGSAAEQEQARRVQAVRGRG-THLLCTLLLGQAGANAALAGWLYASLPPGVGDPGEDSGEAGVHFPWLPALVCTGAVFLGAEICPYSVCSRHGLAIASHSVCLTRLLMAAAFPVCYPLGRLLDWALRQEISTFYTRE--KLLETLRAADPYSDLVKEELNIIQGALELRTKVVEEVLTPLGDCFMLRSDAVLDFATVSEILRSGYTRIPVYEGDQRHNIVDILFVKDLAFVDPDDCTPLLTVTRFYNRPLHCVFNDTRLDTVLEEFKKGKS-HLAIVQRVNNEGEGDPFYEVMGIVTLEDIIEEIIKSEILDETDLYTDNRKKQRVPHRERRRHDFSLFKLSDSEIRVKISPQLLLATHRFMATEVEPFKSLYLSEKILLRLLKHPNVIQELKFDERNKKAPEHYLYQRNRPVDYFVLLLQGKVEVEVG--KEGLRFENGAFTYYGVPAIMTSACSDNDVRKVGSLAGSSVFLNRSPSRCSGLNRSESPNRERSDFGGSNTQLYSSSNNLYTPDYSVHILSDVQFVKITRQQYQNALTACHMDSSPQSPDMEAFTDGDSTKAPTTRGTPQTPKDDPVLTLLSNRTSLPCSRSDGLRSPGEVVYLRMEEMAFPQEEMPNFEEHRSQQVSLSPVAVPTTAASDPECCNIHLDPEASPCSSDSEENMGKKLLRTLSGRKRKKSADGERASEENSNLTPLIT", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9NRU3-1", "uniprot_id": "CNNM1_HUMAN", "id": "Q9NRU3-1", "name": "Metal transporter CNNM1", "aln": "MAAAAAAAAAVGVRLRDCCSRGAVLLLFFSLSPRPPAAAAWLLGLRPEDTAGGRVSLEGGTLRAAEGTSFLLRVYFQPGPPATAAPVPSPTLNSGENGTGDWAPRLVFIEEPPGGGGVAPSAVPTRPPGPQRCREQSDWASDVEVLGPLRPGGVAGSALVQVRVRELRKGEAERGGAGGGGKLFSLCAWDGRAWHHHGAAGGFLLRVRPRLYGPGGDLLPPAWLRALGALLLLALSALFSGLRLSLLSLDPVELRVLRNSGSAAEQEQARRVQAVRGRG-THLLCTLLLGQAGANAALAGWLYTSLPPGFGGTGEDYSEEGIHFPWLPALVCTGAVFLGAEICPYSVCSRHGLAIASHSVCLTRLLMAAAFPVCYPLGRLLDWALRQEISTFYTRE--KLLETLRAADPYSDLVKEELNIIQGALELRTKVVEEVLTPLGDCFMLRSDAVLDFATVSEILRSGYTRIPVYEGDQRHNIVDILFVKDLAFVDPDDCTPLLTVTRFYNRPLHCVFNDTRLDTVLEEFKKGKS-HLAIVQRVNNEGEGDPFYEVMGIVTLEDIIEEIIKSEILDETDLYTDNRKKQRVPQRERKRHDFSLFKLSDTEMRVKISPQLLLATHRFMATEVEPFKSLYLSEKILLRLLKHPNVIQELKFDEKNKKAPEHYLYQRNRPVDYFVLLLQGKVEVEVG--KEGLRFENGAFTYYGVPAIMTTACSDNDVRKVGSLAGSSVFLNRSPSRCSGLNRSESPNRERSDFGGSNTQLYSSSNNLYMPDYSVHILSDVQFVKITRQQYQNALTACHMDSSPQSPDMEAFTDGDSTKAPTTRGTPQTPKDDPAITLLNNRNSLPCSRSDGLRSPSEVVYLRMEELAFTQEEMTDFEEHSTQQLTLSPAAVPTRAASDSECCNINLDTETSPCSSDFEENVGKKLLRTLSGQKRKRSPEGERTSEDNSNLTPLIT", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A0B7P9G0-1", "uniprot_id": "UEX_DROME", "id": "A0A0B7P9G0-1", "name": "Unextended protein", "aln": "--------------MNTYFISFITIIIFANGINGTSVDTSNKLLLQKANDFNLSQNLSSSRTRRTIANSFRIVGIRLEDETVETKNGIPTVLVDKEQQFRVFGSGLEENTAITFTNEKNDYGGPCLKPATDLFTPIEVSSNGFSALYSVKFPSFINEFFICAKTAEKTTNHSKAATT--------------TPLEHQGNSD----FLKIKTFEP----LIPVWLAIIIIVTCLGFSALFSGLNLGLMSMDRTELKILRNTGTEKEKKYASKIAPVRDQG-NYLLCSILLGNVLVNSTFT-ILLDGLTSG----------------LFAVIFSTLAIVLFGEITPQAVCSRHGLAIGAKTILVTKTVMAITAPLSYPVSRILDKLLGEEIGNVYNRE--RLKELVRVTNDVNDLDKNEVNIISGALELRKKTVADVMTHINDAFMLSLDALLDFETVSEIMNSGYSRIPVYDGD-RKNIVTLLYIKDLAFVDTDDNTPLKTLCEFYQNPVHFVFEDYTLDIMFNQFKEGTIGHIAFVHRVNNEGDGDPFYETVGLVTLEDVIEELIQAEIVDETDVFVDNRTKTRR--NRYKKADFSAFAERREVQTVRISPQLTLATFQYLSTAVDAFKKDVISELILRRLLN-QDVFHNIKTKGKSKDDPSLYIFTQGKAVDFFVLILEGRVEVTIG--KEALMFESGPFTYFGTQALVPNVVIDS------------------PTQMGSLQSLNMDSKIR---------------QSFVPDYSVRAISDVIYITIKRVLYLTAKKATLLEKSRKSGTFSSETFDDEVERLLHS---ITENEKPSCFAQNQSTRRLSNRS---INSSPTNMNRSPDFVYNSVDEAIQDDTKLKNIKHADNVTTSISLVAAELEDLHSGEQDTTAAS-------MPLLPKLDDKFESKQSKP---------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q12296-1", "uniprot_id": "MAM3_YEAST", "id": "Q12296-1", "name": "Protein MAM3", "aln": "------------------------------------------------------MSFLPLRSRSRSGAPHWVYIILYHIFTIPKIYSLP------------------------------------LLSGSHVLNSRDVADSGHSVGDEASVTTYY-----------------------------------------------------------------------IISIILVLLGGVFAGLTLGLMGQDEVYLKVISTSGSNSEKKLAKRVLDLISRGKHWVLVTLLLSNVITNETLPIVLDRCLGGG----------------WQAVVSSTILIVIFGEIIPQSVCVKYGLQVGAFFCPFVLVLMYLMYPVAYPIATLLDYMLGEDHGTMYKKSGLKTLVTLHRTMGVERLTKDEVTIISAVLDLKAKRVEEIMTPIENVFTMSADTILDDKTVEKIFNSGFSRIPIFLPNEPNNFIGMLLVRVLISYDPDDCLPIS---HFPLATLPETSPNTSCLNILNYFQEGKA-HMCVVSKEPGSSHG-----AIGVLTLEDVIEELIGEEIVDESDVFVDMHQHIMR-------------QQPGPLSKRHITSYLHHLYTSSHKEHKAADQADESSPLLSPSNSNHPSEHPQQDLNNKSWKQKSNDGYDRSNAVLSPTPQVTEHGTIIPSNLASNPLNVNKSFVTIKKPANVPKIITTHTPHS-----------SKEPSPAPHSNDKSLSAEEQ----------------QLLSDHAELSRQAVLHTQRSGQPTQVTTSTKTTRNSPDSISIPNSGANHGNENQNVTISTSYQNTKN-----GIVESVITVKGVPKTIIGPAKDWDESKSEYGNENINQENSNRSDDRESSSSNASLFSSIKNKFKNENANNNDRSNFT-------DSLSRTSNYDANGSSSTIKR-------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .: * . .. : . . .... . .. .. : : : :..:*:** *.*:. * . *::: .:*: *:: * :: : .:* :* ::**.:. .* ::. * * * ..: .* :.: .** * :** ::** :.: .. :* *:.**:. :** * :: ...*.:. : :: : . * *:*:.**...*:*: * * :::* : : * : *::** **.:*:.**::***:: : :*:: :* :: * *.** *: .* .: . : ::: *::*. *:..* : ....* .:*::****:***:* **:**:*::.* : : :*:. * . : * : : . : . . :. . . : :...* . : : : . . . .*. * :.. *: : . . : .*:: . * . . : .: .* .* : .. : : . . :. . . . : . : :. .: : .. : : : : . : . : * . . . .. ", "identical_positions": 97, "similar_positions": 235, "identity": "10.14%" }, { "cls_id": "homologset.agr.MGI:1891369", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZJZ8-1", "uniprot_id": "D3ZJZ8_RAT", "id": "D3ZJZ8-1", "name": "Calpain-12", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MASGNRKVTIQLVDDGAAAGAGGPQLFKGQNYEAIRAACLDSGILFRDPCFPAGPDALGYDKLGPDSEKAKGVEWKRPHEFCAEPQFICEDMSRTDVCQGSLGNCWLLAAAASLTLYPRLLYRVVPPGQGFQDGYAGVFHFQLWQFGRWVDVVVDDKLPVRDGKLLFVRSEQRNEFWAPLLEKAYAKLHGSYEVMRGGHMNEAFVDFTGGVGEVLYLRQNTP-GVFAALRHALAKESLVG----ATALSDRGEIRTDEGLVKGHAYSVTGTHKMSLGFT----KVRLLRLRNPWG-RVEWSGPWSDSCPRWDMLP-SEWRDALLVKKEDGEFWMELQDFLTHFNTVQICSLSPEVLG----PSPAGGGWHIHTFQGRWVRGFNSGGSQPSAENFWTNPQFRLTLLEPDEEEDEDDE--EGPWGGWG---------AAGAR-PARGGRVPKCTVLLSLIQRNRRCLRAKGLTYLTVGFHVFQIPEELLGLWDSPRSRALLPGLLRADRSVFCARRDVSRRCRLPPGHYLVVPSASRVGDEADFTLRIFSERSHTAVEIDDVISADLDALQA-----PYKP------LELELAQLFLELAGEEEELNALQLQTLISIALEPARNN--------------------------------------------------------------------------TRTSGEIGLRTCEQLVQCFGRGQR--LALYHFQELWGHLLSWQATFDKFDEDASGTMNSCELRLALTAAGFHLNNQLTQALTSRYRNSRLRVDFEHFVCCAARLTCIFRHCCQHLDGGEGVVCLTHKQWSEVATFS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9ER56-1", "uniprot_id": "CAN12_MOUSE", "id": "Q9ER56-1", "name": "Calpain-12", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MASGNRKVTIQLVDDGAGTGAGGPQLFKGQNYEAIRRACLDSGILFRDPCFPAGPDALGYDKLGPDSEKAKGVEWKRPHEFCAEPQFICEDMSRTDVCQGSLGNCWLLAAAASLTLYPRLLYRVVPPGQGFQDGYAGVFHFQLWQFGRWVDVVVDDKLPVREGKLMFVRSEQRNEFWAPLLEKAYAKLHGSYEVMRGGHMNEAFVDFTGGVGEVLYLRQNTP-GVFAALRHALAKESLVG----ATALSDRGEIRTDEGLVKGHAYSVTGTHKMSLGFT----KVRLLRLRNPWG-RVEWSGPWSDSCPRWDMLP-SEWRDALLVKKEDGEFWMELQDFLTHFNTVQICSLSPEVLG----PSPAGGGWHIHIFQGRWVRGFNSGGSQPSAENFWTNPQFRLTLLEPDEEEDDDDE--EGPWGGWG---------AAGARGPARGGRVPKCTVLLSLIQRNRRCLRAKGLTYLTVGFHVFQIPEELLDLWDSPRSRALLPGLLRADRSVFCARRDVSRRCRLPPGHYLVVPSASRVGDEADFTLRIFSERSHTAVEIDDVISADLDALQA-----PYKP------LELELAQLFLELAGEEEELNALQLQTLISIALEPARAN--------------------------------------------------------------------------TRTPGEIGLRTCEQLVQCFGRGQR--LSLHHFQELWGHLMSWQATFDKFDEDASGTMNSCELRLALTAAGFHLNNQLTQSLTSRYRDSRLRVDFERFVGCAARLTCIFRHCCQHLDGGEGVVCLTHKQWSEVATFS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6ZSI9-1", "uniprot_id": "CAN12_HUMAN", "id": "Q6ZSI9-1", "name": "Calpain-12", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MASSSGRVTIQLVDEEAGVGAGRLQLFRGQSYEAIRAACLDSGILFRDPYFPAGPDALGYDQLGPDSEKAKGVKWMRPHEFCAEPKFICEDMSRTDVCQGSLGNCWFLAAAASLTLYPRLLRRVVPPGQDFQHGYAGVFHFQLWQFGRWMDVVVDDRLPVREGKLMFVRSEQRNEFWAPLLEKAYAKLHGSYEVMRGGHMNEAFVDFTGGVGEVLYLRQNSM-GLFSALRHALAKESLVG----ATALSDRGEYRTEEGLVKGHAYSITGTHKVFLGFT----KVRLLRLRNPWG-CVEWTGAWSDSCPRWDTLP-TECRDALLVKKEDGEFWMELRDFLLHFDTVQICSLSPEVLG----PSPEGGGWHVHTFQGRWVRGFNSGGSQPNAETFWTNPQFRLTLLEPDEE-DDEDE--EGPWGGWG---------AAGARGPARGGRTPKCTVLLSLIQRNRRRLRAKGLTYLTVGFHVFQIPEELLGLWDSPRSHALLPRLLRADRSPLSARRDVTRRCCLRPGHYLVVPSTAHAGDEADFTLRVFSERRHTAVEIDDVISADLQSLQG-----PYLP------LELGLEQLFQELAGEEEELNASQLQALLSIALEPARAH--------------------------------------------------------------------------TSTPREIGLRTCEQLLQCFGHGQS--LALHHFQQLWGYLLEWQAIFNKFDEDTSGTMNSYELRLALNAAGFHLNNQLTQTLTSRYRDSRLRVDFERFVSCVAHLTCIFCHCSQHLDGGEGVICLTHRQWMEVATFS", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M2BLA7-1", "uniprot_id": "A0A8M2BLA7_DANRE", "id": "A0A8M2BLA7-1", "name": "", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MS------ELGSIDN--------PVKFKDQDYEVLLQTCLKSAVLFSDSVFAANQSSLG---LPADPDPKKAVKWLRPKEITSNAVFVEGTMGTTDICQGQLGNCWLLAALSCLTMHPTLFVKVVPAGQSLSESYAGIFRFKFWQYGEWVEVVVDDRLPVREGRLLFSYSRTSNEFWSALVEKAYAKLIGSYGSLKGGIISEGMEDFTGGIAYSLPVSSRPPRMLWKAITAALARNSLLSCFIHATTVKDIG-TVTPEGLIKGHAYAITETGKVKKASE----EVFLLRLRNPWG-FVEYCGPWSDKCKDWDFVDNTEKTKLELAKVEDGEFWISIEDFCRFYNTVEMCSVDPDSMSGEESEDTSTSSWTLSLHQGTWVPMCSAGGSRRYPKSFWKNPQYQMILSEKDVDDHDYGEGEEGDDGGDGEEDEDVSLLPPVSKTSKPGEKKKKCTVLVELLQKYRR--QKDKVNFLYIAFHIYKVPPELKDSPGSLDQQFFSSNRAISRSGKYRSIRSVWRKVHLEPGSYVILASTYRPNQQGEFFLRIYTKTGNIQGFQDFPCTNNYSAMVMSK---PVLPE-----DQYRVQKWFEEKAGSDERVNAVQFMNLVNSVLEKD---------------------------------------------------------------------------------YELPLETCRQLIFGEDTGGRGRLDRAQAEKLLSSLRNLQSIFFQFDEDSSGTMSPFELSLALNAAGVECDSVVVQMLWERFGAGEQYLPFYGFVSCVARLQVLFDLYEAETNQEVKDKGINAWLLKLLAV--", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q11002-1", "uniprot_id": "CANA_DROME", "id": "Q11002-1", "name": "Calpain-A", "aln": "MDDLRGFLRQAGQEFLNAAGEAAMGAAKDVVG-------------------------SVINEIFIKKEADTKR-------------------------------------------------------------------------------------------------------------------------------------------------VLPSIKNMRVLGEKSSSLGPYSEVQ-DYETILNSCLASGSLFEDPLFPASNESLQFS-----RRPDRHIEWLRPHEIAENPQFFVEGYSRFDVQQGELGDCWLLAATANLTQESNLFFRVIPAEQSFEENYAGIFHFRFWQYGKWVDVIIDDRLPTYNGELMYMHSTEKNEFWSALLEKAYAKLHGSYEALKGGSTCEAMEDFTGGVSEWYDLKEAPG-NLFTILQKAAERNSMMG--CSIEPDPNVTEAETPQGLIRGHAYSITKVCLIDIVTPNRQGKIPMIRMRNPWGNEAEWNGPWSDSSPEWRYIPEEQKAEIGLTFDRDGEFWMSFQDFLNHFDRVEICNLSPDSLTEDQ-QNSGKRKWEMSMYEGEWTPGVTAGGCRNFLDTFWHNPQYIITLVDPDEEDEE------GQ-----------------------------CTVIVALMQKNRRSKRNMGMECLTIGFAIYSLNDRELEN-RPQGLNFFRYKSSVGRSPHFINTREVCARFKLPPGHYLIVPSTFDPNEEGEFIIRVFSETQNNMEENDDHVGYGGKADTITPGFPTPKP---IDPQKEGLRRLFDSIAGKDMEVDWMELKRILDHSMRDDLPKPVVFNRFSNNMAFETQAAGPGDDGAGACGLLSLICGPFLKGTPFEEQLGMNDQSNKRLIGDNPADGGPVTANAIVDETHGFSKDVCRSMVAMLDADKSGKLGFEEFETLLSEIAKWKAIFKVYDVENTGRVSGFQLREALNSAGYHLNNRVLNVLGHRYGSRDGKIAFDDFIMCAVKIKTYIDIFKERDTEKNETATFTLEEWIERTIYS", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VT65-1", "uniprot_id": "CANB_DROME", "id": "Q9VT65-1", "name": "Calpain-B", "aln": "MYGIDNYPKNYHASGIGLVNLAALGYSKNEVSGGNEGGGAPKPKAGLYPSLPYPSSESVGGMPYVVKQTSHAQNASYAGPTMGMGMPVPEAPSAPAPYPSATPYPGSGLYPSLPSANVSSLPYPTAPMAPYPTGMPYPTGMPQPNLPYPAAPLAPYPSAMPGLPGMPMPYAPMPTSPAPQHNIGFPALPYPTAPPPESAPTQEEEPSVGVAELSFTSVKVPENQNMFWMGRKATSARQNSVSKGDFQSLRDSCLANGTMFEDPDFPATNASLMYS-----RRPDRYYEWLRPGDIADDPQFFVEGYSRFDVQQGELGDCWLLAAAANLTQDSTLFFRVIPPDQDFQENYAGIFHFKFWQYGKWVEVVIDDRLPTYNGELIYMHSTEKNEFWSALLEKAYAKLHGSYEALKGGTTCEAMEDFTGGVTEWYDIKEAPP-NLFSIMMKAAERGSMMG--CSLEPDPHVLEAETPQGLIRGHAYSITKVCLMDISTPNRQGKLPMIRMRNPWGNDAEWSGPWSDSSPEWRFIPEHTKEEIGLNFDRDGEFWMSFQDFLNHFDRVEICNLSPDSLTEDQ-QHSSRRKWEMSMFEGEWTSGVTAGGCRNFLETFWHNPQYIISLEDPDDEDDD------GK-----------------------------CTAIVALMQKNRRSKRNVGIDCLTIGFAIYHLTDRDMQV-KPQGLNFFKYRASVARSPHFINTREVCARFKLPPGHYLIVPSTFDPNEEGEFIIRVFSETRNNMEENDDEVGFGETDDRIAPSLPPPTPKEEDDPQRIALRRLFDSVAGSDEEVDWQELKRILDHSMRDVMVG-----------------------------------------------------------------------------SDGFSKDAVRSMVAMLDKDRSGRLGFEEFEALLTDIAKWRAVFKLYDTRRTGSIDGFHLRGALNSAGYHLNNRLLNALAHRYGSREGQIPFDDFLMCAIKVRTFIEMFRERDTDNSDTAFFNLDDWLERTIYS", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .:: : :** .. :* *. *.* :* : :* ** :: :. *. . *: **.**:**:*** : ** . *: :*:*. *.:...***:*:*::**:*.*::*::**:**. :*.*:: * ****:.*:******* *** ::** *.: *****: : . . :: : * : *::. . . * :**::****::* . : :: ::*:***** .*: *.***.. * : . * .*****:.:.** .:: *::*.:.*: : . * : .:* *. .:**.: ..** ***: : * : * : .: * **.:: *:*: ** : : * :.* :: : . . . : . *.* : * ** *:::.*: .::.:* :*:::: : * . . * . : : * . **.: .:: :: ::. :. : . ..:: . . * . : * : . :: * :* :* :. .* **.:** . :. : : * *: : * *: *. :: : . :. : ", "identical_positions": 150, "similar_positions": 211, "identity": "14.33%" }, { "cls_id": "homologset.agr.MGI:1891372", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9W5B5-1", "uniprot_id": "Q9W5B5_DROME", "id": "Q9W5B5-1", "name": "Gamma-butyrobetaine dioxygenase", "aln": "--------------------------MLSCRQLISRLSLLRQASTFACVR------LCPDYVEVQ-EEQGN--------LLKYPQVWLRDNCQCAECFHAATRARKSHWDRGPLNIPVSQVAYNKERKQLEIIWQDKHRSTFDLGWLRERDFGETGRKHYLEEVYKPPAQLWGKTEFEDVKR---EFQYEDVLE--QDAALRVWLEALAVQGFAILKGAPNDINV---AKKLAERIGYIKRTTYGD-VFEVKS-KPNARNYAYLMTPLPLHTDMPYYEYKAGINILHTLVQSESKGGANT----LTDGFNVASQLQKLHPEDFEVLKSVPVNWFDIGHDG-----DDSKPFHSLWRAPVICLDVDGRFARINQN------------TTKRDSRFSVSLAQAVS------------WYKAYDKFLEIAQSEA--VEFKTQAGDVFVFNNLRMLHGRTAYEDAPGNKRHLVGAYVDWDIIYSKLRTLKFPNAKD--", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VY24-1", "uniprot_id": "Q9VY24_DROME", "id": "Q9VY24-1", "name": "", "aln": "--------------------------MWVPRLLGRSLSQLKTINSAQFSRQISAKIVNESSIEVQPEANSK--------PLTFPGIWLRDNCMCEDCFHGSSKSRKLDWDNFDTRIRPVSLQTDEQSKEVLVKWSDAHESRFSLKWLKERCFEPDKQQEYLRDFYRPTTRHWSGAEFQDIAQ---HFSYDEVMS--QDSVLMQWLQALAIYGVALLRGAPLDEGV---VRRLADRVGFIRRTTYGE-EFVVQA-KPGAQNFAYLSLTLPLHTDLPYYEYKPSVNILHCVVQTDSPGGSNM----LVDGFHVADLLRRDHPEDFERLSRIVVDWNDIGSE-------DGREFHNIWRAPVICLDEEGRYTRINHS------------VPQRDSHFNVPLEEVLP------------WYESYALFVRLAIADS--HAFKTRPGDVLTFNNIRLLHGRTGYDDSEESPRYIVGAYLDWDIIYSRLRVLKKRLTASCQ", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q924Y0-1", "uniprot_id": "BODG_MOUSE", "id": "Q924Y0-1", "name": "Gamma-butyrobetaine dioxygenase", "aln": "------------------------------------MHCA----------ILKAEAVDGAHLMQIFWHDGA--------ESLYPAVWLRDNCQCSDCYLHSAKARKLLLEALDVNIRIDDLTFDR--KKVYITWPNDHYSEFEANWLKKRCFSQQARARLQGELFLPECQYWG---SELQLP---TLNFEDVLN--DDDHAYKWLSSLKKVGIVRLTGAADKRGE---IIKLGKRIGFLYLTFYGH-TWQVQD-KIDANNVAYTTGKLSFHTDYPALHHPPGVQLLHCIKQTVT-GGDSE----IVDGFNVCQKLKEKNPQAFHILSSTFVDFTDIGVD--------YCDFSVQSKHKIIELDDKGQVVRVNFN------------NATRDTVFDVPIERVQP------------FYAALKEFVDLMNSKEYKYTFKMNPGDVITFDNWRLLHGRRSYEAGTEISRHLEGAYADWDVVMSRLRILRQRVTNGN-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9QZU7-1", "uniprot_id": "BODG_RAT", "id": "Q9QZU7-1", "name": "Gamma-butyrobetaine dioxygenase", "aln": "------------------------------------MHCA----------ILKAEAVDGARLMQIFWHDGA--------ESLYPAVWLRDNCQCSDCYLHSAKARKLLLEALDVNIRMDDLTFDQ--KKVYITWPNGHYSEFEANWLKKRCFSQEARAGLQGELFLPECQYWG---SELQLP---TLNFEDVLN--DDDHAYKWLSSLKKVGIVRLTGAADKRGE---IIKLGKRIGFLYLTFYGH-TWQVQD-KIDANNVAYTTGKLSFHTDYPALHHPPGVQLLHCIKQTVT-GGDSE----IVDGFNVCQKLKEKNPQAFSILSSTFVDFTDIGVD--------YCDFSVQSKHKIIELDDKGQVVRINFN------------NATRDTVFDVPIERVQP------------FYAALKEFVDLMNSKEYKYTFKMNPGDVITFDNWRLLHGRRSYEAGTEISRHLEGAYADWDVVMSRLRILRQRVMNGN-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O75936-1", "uniprot_id": "BODG_HUMAN", "id": "O75936-1", "name": "Gamma-butyrobetaine dioxygenase", "aln": "------------------------------------MACT----------IQKAEALDGAHLMQILWYDEE--------ESLYPAVWLRDNCPCSDCYLDSAKARKLLVEALDVNIGIKGLIFDR--KKVYITWPDEHYSEFQADWLKKRCFSKQARAKLQRELFFPECQYWG---SELQLP---TLDFEDVLR--YDEHAYKWLSTLKKVGIVRLTGASDKPGE---VSKLGKRMGFLYLTFYGH-TWQVQD-KIDANNVAYTTGKLSFHTDYPALHHPPGVQLLHCIKQTVT-GGDSE----IVDGFNVCQKLKKNNPQAFQILSSTFVDFTDIGVD--------YCDFSVQSKHKIIELDDKGQVVRINFN------------NATRDTIFDVPVERVQP------------FYAALKEFVDLMNSKESKFTFKMNPGDVITFDNWRLLHGRRSYEAGTEISRHLEGAYADWDVVMSRLRILRQRVENGN-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A1D5NSC9-1", "uniprot_id": "A0A1D5NSC9_DANRE", "id": "A0A1D5NSC9-1", "name": "gamma-butyrobetaine dioxygenase", "aln": "MLSYLARWVSRGAVQALKGTSSRPQLVKTPRIGNQTLAAAPLPFAGGSPGVRQARALDQERLLQIDWDDGS--------CSLYPFTWLRDNCQCPLCTLQSAQARSLLFSHLDVHTGMDHVQLMD--NKVSITWPDQHSSEFDPDWLKKRCFSSEARQALQEELFLNEREYWD---SGLQIP---TADFEEVLH--DDKAALAWLEALRRIGIVYLRGAPAEQGQ---LARLSQRIGYLRLTFYGH-TWQVQD-KPMANNVAYTSGELSLHTDYPALHHPPGVQFLHCVRQADE-GGESE----VVDGFHMAEQLRREDPEAFNILSSLRVDFTDSGAD--------YCDFSVQSKNHIIDVDSSGRVVRINYN------------NATRDSVLDLPLHQVQP------------FYSSLKAFVELLSRPENVFTYRMEPGDVVTFDNWRLLHGRKSYQSRGQNLRHLEGAYLDWDEVMSRLRILRKTVRGDS-", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P23180-1", "uniprot_id": "AIM17_YEAST", "id": "P23180-1", "name": "Probable oxidoreductase AIM17", "aln": "-------------------------MLRSNLCRGSRILARLTTTPRTYTSAATAAAANRGHIIKTYFNRDSTTITFSMEESSKPVSVCFNNVFLRDASHSAKLVTTGELYHNEKLTAPQDIQISEDGKSLVVKWKDGGHHQFPLQFFIDYKGSSFVSPATRKQESRYRPQLWNKRILKDNVKDLLSVSYNEFIDPKDDSKLFQTLVNLQKFGIAFISGTPSSSSEGLTIQKICERIGPIRSTVHGEGTFDVNASQATSVNAHYANKDLPLHTDLPFLENVPGFQILQSLPATEGEDPNTRPMNYFVDAFYATRNVRESDFEAYEALQIVPVNYIYENGDKRYYQSKPLIEHHDINEDNTLLGNYEALIKCINYSPPYQAPFTFGIYDKPSDLNNNLDLNLITTPAKLTERFLFKSFIRGLNLFESHINDFNNQFRLQLPENCCVIFNNRRILHAN---SLTSSNQQWLKGCYFDSDTFKSKLKFLEEKFPHDK-", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : * :* . : . : :.: : * : * :: . : . *. .:::.: * * * *.. : *:. . . :: .*:* : * :*. : *: : : * * *.:*** * . ...::*: : : . . ..*.* ::. . : : *. *:: . : . . : : .. :* . * .: : . : . * : . . *:* *:**.. . : : *.* * * . *:*: *. . ", "identical_positions": 42, "similar_positions": 99, "identity": "8.5%" }, { "cls_id": "homologset.agr.MGI:1891374", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q91Y44-1", "uniprot_id": "BRDT_MOUSE", "id": "Q91Y44-1", "name": "Bromodomain testis-specific protein", "aln": "----------MS--LPSRQ-TAIVNPP-----PPEYINTKKSGRLTNQLQFLQRVVLKALWKHGFSWPFQQP---VDAVKLKLPDYYTIIKTPMDLNTIKKRLENKYYEKASECIEDFNTMFSNCYLYNKTGDDIVVMAQALEKLFMQKLSQMPQEEQVVGGKERIKKDIQQKIAVSS--------------------------------------------------------------------AKEQIPSKAAENVFKRQEIPSGLPDISLSPLNMAQEAP----------------------------------------------------------------------------------------------------------------PICDSQSLVQITKGVKRRADTTTPTTS--IAKASSESPPTLRETKPVNMPVKE-----------------NTVKNVLP---------------DSQQQHKVLKTVKVTEQLKHCSEILKEMLAKKHLPYAWPFYNPVDADALGLHNYYDVVKNPMDLGTIKGKMDNQEYKDAYEFAADVRLMFMNCYKYNPPDHEVVAMARTLQDVFELHFAKIPDEP----------------------IESMHACHLTTNSAQALSRESSSEASSGDASS----EDSEDERVQHLAKLQEQLNAVHQQLQVLSQVPLRKLKKKNEKSKRAP--------------------------------------------------------------------------------------------------------------------------------------------------KRKKVNNRDENPRK--------------------------------------------KPKQMKQKEKAK------------------INQPKKKKP---LLKSEEEDNAKPMNYDEKRQLSLDINKLPGDKLGRIVHIIQSREPS--LRNSNPDEIEIDFETLKASTLRELEKYVLACLRKRS-----LKPQAKKVVRSKE-----------ELHSEKKLELERR---------------------------------LLDVNN-------QLNCRKRQTKR--------------------------------------------------------------------------------------------------------------PAKVEKPPPPPPPPPPPPPPPELASGSRLTDSSSSSGSGSG---------------------SSSSSSGSSSSSSSSG------------------------SASSSS----------------------DSSSSDSSDS-EPEIFPKFTGVKQNDLPPKENIK----------------QIQSSVQ------------------------------DITSAEAP---------------------------------------------------LAQQSTAPCGAPGKHSQQMLGCQVTQH-LQATENTASVQTQPLSGDCKRVLLG------------------------------------------------PPVVHTSAES-LTVLEPECHAPA---QKDIKIKNADSWKSLG--------KPVKAS-SVLKSSDELFNQFRKAAIEKE---------------VKARTQEQMRKHLEHNAKDPKVSQENQREPGSGLTLESLSSK--VQDKSLEEDQSEQQ---PPSEAQDVSKLWLLKDRNLAREKE--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------QERRRREAMAGTIDMTLQSDIMTMFENNFD", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D4A7T3-1", "uniprot_id": "BRDT_RAT", "id": "D4A7T3-1", "name": "Bromodomain testis-specific protein", "aln": "----------MS--LPSRQ-MAIVNPP-----PPEYINAKKTGRLTNQLQFLQRVVLKALWKHSFSWPFQQP---VDAAKLKLPDYYTIIETPMDLSTIKKRLENRYYEKASECVGDFNTMFSNCYLYNKPGDDIVVMAQALEKLFMQKLSQMPQEEQIVGGKERMKKDIQQKTAVSS--------------------------------------------------------------------AKEQTPSKSAENVFKRQEIPAGFPDVCLSPLNMAQEAP----------------------------------------------------------------------------------------------------------------PTCDSQTVVQITKGVKRRADTTTPTTS--SAKASSESPPPLREAKPANAPVKE-----------------NTVKSVLP---------------DSQQQHRVLKTVKVTEQLKHCSEILKEMLAKKHLPYAWPFYNPVDVDALGLHNYYDIVKNPMDLGTIKGKMDKQEYKDACEFAADVRLMFMNCYKYNPPDHEVVTMARMLQDVFEMHFAKIPDEP----------------------VESMRACHLTTNSAKALSRESSSEASSGDCSS----EDSEDERVQRLAKLQEQLNAVHQQLQVLSQVPLRKLKKKNEKSKRAP--------------------------------------------------------------------------------------------------------------------------------------------------KRKKVN-RDENPKK--------------------------------------------KAKQMKQKEKAK------------------SNQPKKKKP---LLKLEEEDNAKPMNYDEKRQLSLDINKLPGDKLGRIVHIIQSREPS--LRNSNPDEIEIDFETLKASTLRELEKYVLACLRKRS-----LKPHAKKVVRSKE-----------ELHSEKKLELERR---------------------------------LLDVNN-------QLNCRKRQTKR--------------------------------------------------------------------------------------------------------------PAKVAVSPRPPLPPPPPPPP-ELASGSRLSDSSSSS--------------------------SSSGSGSSSSSSSSSG------------------------SGSSSS----------------------DSSSSDSSDS-EPEISPKFTGVKQNDLPSKENTK----------------QIQCSVP------------------------------DITSAETA---------------------------------------------------LVQQSTGPCGAPGKPPQQMPGCQVPHH-LQATESTASVQTQPLAGDCKRVLHG------------------------------------------------PPVVHASAES-HTVLELQCHAPV---QKDIKIKNADSWKSLG--------KPVKAS-SVLKSSDELFNQFRKAAIEKE---------------VKARTQEQIRKHLEHSAKDPKVSQESQREFGSGFTPESSSNK--VQGRSHGEEQSEQQQLPSPSETQDISKLWLLKDRNLAREKE--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------QERRRREAMAGTIDMTLQSDIMTMFENNFD", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q58F21-1", "uniprot_id": "BRDT_HUMAN", "id": "Q58F21-1", "name": "Bromodomain testis-specific protein", "aln": "----------MS--LPSRQTAIIVNPP-----PPEYINTKKNGRLTNQLQYLQKVVLKDLWKHSFSWPFQRP---VDAVKLQLPDYYTIIKNPMDLNTIKKRLENKYYAKASECIEDFNTMFSNCYLYNKPGDDIVLMAQALEKLFMQKLSQMPQEEQVVGVKERIKKGTQQNIAVSS--------------------------------------------------------------------AKEKSSPSATEKVFKQQEIPSVFPKTSISPLNVVQGAS----------------------------------------------------------------------------------------------------------------VNSSSQTAAQVTKGVKRKADTTTPATS--AVKASSEFSPTFTEKSVALPPIKE-----------------NMPKNVLP---------------DSQQQYNVVKTVKVTEQLRHCSEILKEMLAKKHFSYAWPFYNPVDVNALGLHNYYDVVKNPMDLGTIKEKMDNQEYKDAYKFAADVRLMFMNCYKYNPPDHEVVTMARMLQDVFETHFSKIPIEP----------------------VESMPLCYIKTDITETTGRENTNEASSEGNSS----DDSEDERVKRLAKLQEQLKAVHQQLQVLSQVPFRKLNKKKEKSKKEK--------------------------------------------------------------------------------------------------------------------------------------------------KKEKVNNSNENPRK--------------------------------------------MCEQMRLKEKSK------------------RNQPKKRKQQFIGLKSEDEDNAKPMNYDEKRQLSLNINKLPGDKLGRVVHIIQSREPS--LSNSNPDEIEIDFETLKASTLRELEKYVSACLRKRP-----LKPPAKKIMMSKE-----------ELHSQKKQELEKR---------------------------------LLDVNN-------QLNSRKRQTK----------------------------------------------------------------------------------------------------------------------------SDKTQPSKAVENVSRLSESSSSS-------------------------------------SSSSE------------------------SESSSS----------------------DLSSSDSSDS-ESEMFPKFTEVKPNDSPSKENVKKMKNECIPPEGRTGVTQIGYCVQ------------------------------DTTSANTT---------------------------------------------------LVHQTTPSHVMPPNHHQLAFNYQELEH-LQTVKNISPLQILPPSGDSEQLSNG------------------------------------------------ITVMHPSGDSDTTMLESECQAPV---QKDIKIKNADSWKSLG--------KPVKPS-GVMKSSDELFNQFRKAAIEKE---------------VKARTQELIRKHLEQNTKELKASQENQRDLGNGLTVESFSNK--IQNKCSGEEQKEHQ---QSSEAQDKSKLWLLKDRDLARQKE--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------QERRRREAMVGTIDMTLQSDIMTMFENNFD", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "I3IS77-1", "uniprot_id": "I3IS77_DANRE", "id": "I3IS77-1", "name": "", "aln": "----------MSDVKPPQHFTMNGNPP-----PPEFKNPKKPGRLTNHLQYIEKVVIRALWKHHFSWPFRQP---VDAVRLNLPDYYTIIKNPMDLTTIRKRLENNYYWKAMECVEDFNTMFTNCYVYNRPGDDIVLMAQVLEKLFLEKVAEMPEEEYEISALTTKGPVKGARKSTIG--------------------------------------------------------------------LKKRPPSPMSEVVFQQT-------VTVIPPDALHTIPS----------------------------------------------------------------------------------------------------------------APLSAQLTAKLKNGVKRKADTTTPSAS--SIPS-CESSSCVTEPKVLKLFSRR-----------------GSGRPIKPPCKD---------LPESPPQHQVGRRTKLSERLKYCNAILKEMFSKKHSAYAWPFYKPVDAETLGLLDYHEIIHQPMDMSTIKKKMEAREYTDALQFAADMRLMFSNCYKYNPPGHEVVSMARKLQDVFEFRFSKIPDEPKN-----------------ANPVSSHNRVKKERARSPSSSESSDSESSSPENSSD-TEEEDEEERAHRLASLEEQLKAVREQLQLLTQTPLLKPKKKEKSKKKKK--------------------------------------------------------------------------------------------------------------------------------------------------KERESSKRKGEEMK--------------------------------------------KPAKILKRSSSS------------------KSSGRKESR---ACDSEEEMNTLPMSYEEKRQLSLDINKLPGDKLGKVVNIIKAREPL--LRDTDPEEIEIDFETLKPSTLRALECYVVGCLRKKTKETNKNKPPKKSKIKEKDKDLQ---HATGEQNSHKKTKIETDGEIKDTTHPSRLSDSSSSSSSSDSSSSDSSSSDSCDSDS-------EQKTKRKQSKG--------------------------------------------------------------------------------------------------------------PGHANKIKKKALRQANAEVKDSSSASGVMCQSRPSSLVSETGSKDLFASQHAKHPVEDITAITALHSRLPPQPSRPSG------------------------KAAALPRKIWTTPSPLSLPPDQALSPLYNASATSPCKD-HTIIPAKSSPESVTPDPPNSLPKDPLFPCSPLLPPPDMQVSQVGPP------------------------------SSVAAKIPPQKSEKEGIPP---------------------------------------LLSPLTSPSAAMPATGSQSTSSSQFEQCRLLSPLHESPLASMRNEQDCPETPEES----------------------------------------SVHLHKIHGAKHDDNELCKSIQDAKSNLP----KKDIVLKHADSWTSLG--------KLATQTPCTIKSSKESFQQFRKVAMEKE---------------ERERARKLQLEAGREKSSTDKSCLTQQPQ-KAKLECQPSKPE--VESAELPLMAAILDTP-KAPEPSSVLQNSVDREREMARKRE--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------QERRRREAMSGVIDMTMQRDIMATFEKNLE", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P13709-1", "uniprot_id": "FSH_DROME", "id": "P13709-1", "name": "Homeotic protein female sterile", "aln": "----------MSSSEPPPRYEPPVEPVNGIVQPPVIPPAERPGRNTNQLQYLIKTVMKVIWKHHFSWPFQQP---VDAKKLNLPDYHKIIKQPMDMGTIKKRLENNYYWSAKETIQDFNTMFNNCYVYNKPGEDVVVMAQTLEKVFLQKIESMPKEELELEPVTAKGGKKKQRAPATPKSSSGGAGASTGSGTSSAAVTSGPGSGSTKVSVAASSAQQSGLQGATGAGGGSSSTPGTQPGSGAGGAIAARPVSAMGGTVSSTAGGAPSIPPISTMPPHTVPGSTNTTTTAMAGGVGGPGAAGANPNAAALMASLLNAGQTGAYPGAPGQTAVNSSSLLDGSTAAVAAAAAAAAAAAAAAGGAAGAAGGAGTIPAVAVNAANAVQAYVNAGVSVGVDAVIPPQQPAKIKKGVKRKADTTTPTAN--AFESPYTQMDSKSAKIATRRESNRQD-----------LTFQGSGYNMSPLGVSGVPGLGGLVAGGVAGVAVAKNKEKLSDALKSCNEILKELFSKKHSGYAWPFYKPVDAEMLGLHDYHDIIKKPMDLGTVKRKMDNREYKSAPEFAADVRLIFTNCYKYNPPDHDVVAMGRKLQDVFEMRYANIPDEPVANAAHHHGHGHGHGHGHGHGHGHGHGHGHGHGYGGSSSLKHDASDSSSEDSSDTENESNSDEERSARLKMLESKLLGLQEEIRKLSEEASAKKKAKKKLKEKKKSIGGGSGSGSASHHCHATGGGANAGGAGGPGSGGHGSVSVPGGVGSLGPGGAGGANLNALLGGSLVGHGGAAVAGGVPNVGALHSQVHDVAMAFSQMAGGGAAAGAGFGAGVTAAGASSGGKAGTLAGALAAGAAAGAGGTTAGSGSSKGAKSKGGRGAKGSGAGGVGASNNAAAGNAAGGAAGAAAGAGSVGGVGGAGAAGGGNASKRAKGSSSAGAGGGVGGANASAGGAGARGSSKKKPSQVMNFDSEEEDTAKPMSYDEKRQLSLDINKLPGDKLGRVVHIIQNREPS--LRDSNPDEIEIDFETLKPSTLRELESYVASCLRKKTHKKPSGKSKDEQMAEKKQELEKRLQDVTGQLGASKKTAKKDESASSKVEAVQPANPVSSSSSSSDSSSSSSSDSSSSDSSDSEAGDGDERPPRKKKSRDSNGSNVNNPSINVVMGGNLPSGALSPTTMLMGLDHVVNSNTPTSQMSNMLGNANPLTAAAMLNNNNKTSLPGSNFGGAPAPGNMMHAGAGVPVAGAAVSASTGQQHNKNGPNDLSKVQPGGPINAALPPHSFAGGTATVATSQSSGGIRIASNLHKPSGLGGGDLGEHHAALAAALTSGINSTGTAGGGINNNGGSNNNANPLGGSHGDAMVNASLASLASGLKQIPQFDDPVEQSLASLEFSAGSTGKSGLTDNFLMQQHLMQPAGPQQQQQQQQQQPFGHQQQQQQQQQQQQQQQQHMDYVTELLSKGAENVGGMNGNHLLNFNLDMAAAYQQKHPQQQQQQAHNNGFNVADFGMAGFDGLNMTAASFLDLEPSLQQQQMQQMQLQQQHHQQQQQQTHQQQQQHQQQHHQQQQQQQLTQQQLQQQQQQQQQQQHLQQQQHQQQHHQAANKLLIIPKPIESMMPSPPDKQQLQQHQKVLPPQQSPSDMKLHPNAAAAAAVASAQAKLVQTFKANEQNLKNASSWSSLASANSPQSHTSSSSSSSKAKPAMDSFQQFRNKAKERDRLKLLEAAEKEKKNQKEAAEKEQQRKHHKSSSSSLTSAAVAQAAAIAAATAAAAVTLGAAAAAALASSASNPSGGSSSGGAGSTSQQAITGDRDRDRDRERERERSGSGGGQSGNGNNSSNSANSNGPGSAGSGGSGGGGGSGPASAGGPNSGGGGTANSNSGGGGGGGGPALLNAGSNSNSGVGSGGAASSNSNSSVGGIVGSGGPGSNSQGSSGGGGGGPASGGGMGSGAIDYGQQVAVLTQVAANAQAQHVAAAVAAQAILAASPLGAMESGRKSVHDAQPQISRVEDIKASPGGQGQSSPAQQSPQDRAAAKRAEQRRAEQERRRREALAGQIDMNMQSDLMAAFEETL-", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q07442-1", "uniprot_id": "BDF2_YEAST", "id": "Q07442-1", "name": "Bromodomain-containing factor 2", "aln": "-------MSRTNMDTRHAHSALLAAPQSATANSRSSNSSSESSSNKNN----INVGVGDDSGNVSAVSIDDGPHFRDIFHYGHEENYKLASSGITNLNSSSHAHQTLSPISISNASTPESFPEHPLGLERETEPALEAEMEAEELPP-----HQSKYLLSSIKATKRLKDARPFLKPVDPIALNIP---------------------------------------------------------HYFNYVQTPMDLSLIETKLQGNVYHSVEQVTSDFKTMVDNCLNFNGPESS------------------------------------------------------------------------------------------------------ISSMAKRIQKYFEKKLSAMPPRVLPASALKKTSRNRKKNEDMDSPLVIRRSVSTTNDNIGESGNREGVSGGRPKRTIHPPKSK---------DLFDIYENSKPKSKTLQKKFRTCLKILKVLMSKKNSDINFPFLQPVDPIALNLPNYFDVVKNPMDLGTISNNLMNWKYKTIDQFVDDLNLVFYNCFQFNPEGNEVHSMGKKLKELFNFHWLEN----------------------------QDILNEIETDSDLEEDNYSSSYSSDDEYDDE--DINENDITNPAIQYLEQKLKKMEVELQQLKRQELSKLSKER----KRKHL------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------GKTLLRRKAM------------------------KHS----------------VDDLKKSITDKINELSDLEMNGMIRIIKNSLPADEILTSNEDEIEIDLDILDEATIARIYERYFEKKNNNN----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SKRK-LSGN----------------------------------------------------------------------------------------------------------YSTAPTNK--KKKTLKFLEKDE-------------------------------------------------------------------------------------------------------------------------IINNNNYSDSEEDSSD---------------SSDSDSD----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P35817-1", "uniprot_id": "BDF1_YEAST", "id": "P35817-1", "name": "Bromodomain-containing factor 1", "aln": "MTDITPVQNDVDVNGNNVNDDVSSNLKRPIDQGDPSNGLAEEENPANNQLHLKKARLDGDALTSSPAGLAENGIEGATLAANGENGYNATGSGAEDEQQGLKKEEGGQGTKQEDLDE-NSKQELPMEVPKEPAPAPPPEPDMNNLPQNPIPKHQQKHALLAIKAVKRLKDARPFLQPVDPVKLDIP---------------------------------------------------------FYFNYIKRPMDLSTIERKLNVGAYEVPEQITEDFNLMVNNSIKFNGPNAG------------------------------------------------------------------------------------------------------ISQMARNIQASFEKHMLNMPAKDAPP----VIAKGRRSSAQEDAPIVIRRAQTHN---------------GRPKRTIHPPKSK---------DIYP-YESKKPKSKRLQQAMKFCQSVLKELMAKKHASYNYPFLEPVDPVSMNLPTYFDYVKEPMDLGTIAKKLNDWQYQTMEDFERDVRLVFKNCYTFNPDGTIVNMMGHRLEEVFNSKWAD-----------------------------RPNLDDYDSDEDSRTQGDYDDYES--EYSES--DIDETIITNPAIQYLEEQLARMKVELQQLKKQELEKIRKERRLARGSKKR------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------GKRSKGRSGS------------------------KNASSKGRRDKKNKLKTVVTYDMKRIITERINDLPTSKLERAIDIIKKSMPN----ISEDDEVELDLDTLDNHTILTLYNTFFRQYESSS----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------GASNGLDGTSGVTRD---------------------------------------------------------------------------------------------------ASSLSPTSAGSRKRRSKALSQEEQSRQIEK------------------------------------------------------------------------------------------------------------------IKNKLAILDSASPLSQNGSPGQIQSAAHNGFSSSSDDDVSSESEEE--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . . . *: .. : . : : :. : .: . :: : ::: .: : . . . : : . *. : * . : . :: * :** :::**: :** :*** :.* *.: :::***:.*: :: :* .* *:.*:* **: :** . * *.: *:::*: :: . . * .. :. : *:.:* :. ::: *.. * :. : .. . : *: :: **.*. :: : **: * :: :*:*:*:: *. *: : .. : . . ", "identical_positions": 49, "similar_positions": 121, "identity": "2.37%" }, { "cls_id": "homologset.agr.MGI:1891379", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q91WS4-1", "uniprot_id": "BHMT2_MOUSE", "id": "Q91WS4-1", "name": "S-methylmethionine--homocysteine S-methyltransferase BHMT2", "aln": "MAPAGSTRAKKGILERLDSGEVVVGDSGFLFTLEKRGFVKAG---LWTPEA----------VVEHPSAVRQLHTEFLRAGADVLQTFTFSATED---------------NMASK-------WEAVNAAACDLAQEVAGGG----------GALVAGGICQTSLYKYHKDETRIKNIFRLQLEVFARKN-VDFLIAEYFEHVEEAVWAVEVLREVGAPVAVTMCIGPEGDMHDVTPGECAVKLARAGADIIGVNCRFGPWTSLQTMKLMKEGLRDASLQAHLMVQCLGFHTPDCGKGGFVDLPEYPFG-LEPRVATRWDIQKYAREAYNLGIRYIGGCCGFEPYHIRAIAEELAPERGFLPPASEKHGSWGSGLNMHTKPWIRARARREYWENLLPASGRPFCPSLSKPDA---------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q68FT5-1", "uniprot_id": "BHMT2_RAT", "id": "Q68FT5-1", "name": "S-methylmethionine--homocysteine S-methyltransferase BHMT2", "aln": "MAPAGGPRVKKVILERLDSGEVVVGDGGFLFTLEKRGFVKAG---LWTPEA----------VVEYPSAVRQLHTEFLRAGADVLQTFTFSAAED---------------RMESK-------WEAVNAAACDLAQEVADGG----------AALVAGGICQTSLYKYHKDETRIKNIFRLQLGVFARKN-VDFLIAEYFEHVEEAVWAVEVLREVGAPVAVTMCIGPEGDMHGVTPGECAVRLSRAGANIIGVNCRFGPWTSLQTMKLMKEGLRDAGLQAHLMVQCLGFHTPDCGKGGFVDLPEYPFG-LEPRVATRWDIQKYAREAYNLGVRYIGGCCGFEPYHIRAIAEELAPERGFLPPASEKHGIWGSGLDMHTKPWIRARARREYWETLLPASGRPFCPSLSKPDA---------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9H2M3-1", "uniprot_id": "BHMT2_HUMAN", "id": "Q9H2M3-1", "name": "S-methylmethionine--homocysteine S-methyltransferase BHMT2", "aln": "MAPAGRPGAKKGILERLESGEVVIGDGSFLITLEKRGYVKAG---LWTPEA----------VIEHPDAVRQLHMEFLRAGSNVMQTFTFSASED---------------NMESK-------WEDVNAAACDLAREVAGKG----------DALVAGGICQTSIYKYQKDEARIKKLFRQQLEVFAWKN-VDFLIAEYFEHVEEAVWAVEVLKESDRPVAVTMCIGPEGDMHDITPGECAVRLVKAGASIVGVNCRFGPDTSLKTMELMKEGLEWAGLKAHLMVQPLGFHAPDCGKEGFVDLPEYPFG-LESRVATRWDIQKYAREAYNLGVRYIGGCCGFEPYHIRAIAEELAPERGFLPPASEKHGSWGSGLDMHTKPWIRARARREYWENLLPASGRPFCPSLSKPDF---------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q32LQ4-1", "uniprot_id": "BHMT1_DANRE", "id": "Q32LQ4-1", "name": "Betaine--homocysteine S-methyltransferase 1", "aln": "MAPVGS---KRGVLERLNAGEVVIGDGGFVFALEKRGYVKAG---PWTPEA----------AAEHPEAVRQLHREFLRAGSNVMQTFTFYASDD---------------KLENRGNKLSFTGQQINEAACDLAREVANEG----------DALVAGGVSQTPSYLSCKSEEEVKKTFKKQLDVFIKKN-VDLLIAEYFEHVEEAEWAVQVLKATGKPVAATLCIGPDGDMHGVIPGECAVRLVKAGADIVGVNCHFDPLTCVKTVAMMKAAVEKAGLKAHYMTQPLAYHTPDCSCQGFIDLPEFPFA-LEPRILTRWEMQQYAREAYKAGIRYIGGCCGFEPYHIRAVAEELSAERGFLPEASQKHGLWGSGLEMHTKPWVRARARRDYWEKLKPASGRPLCPSMSTPDGWGVTRGHAALMQQKEATTAEQLRPLFQQADAKH", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q12525-1", "uniprot_id": "MHT1_YEAST", "id": "Q12525-1", "name": "Homocysteine S-methyltransferase 1", "aln": "-----MKRIPIKELIVEHPGKVLILDGGQGTELENRGININS--PVWSAAPFTSESFWE-PSSQERKVVEEMYRDFMIAGANILMTITYQANFQ--------------SISENTSIKTLAAYKRFLDKIVSFTREFIGEERYLIGSIGPWAAHVS--CEYTGDYGPHPENIDYYGFFKPQLENFNQNRDIDLIGFETIPNFHELKAILSWDED---IISKPFYIGLSVDDNSLLRDGTTLEEISVHIKGLG--NKINKNLLLMGVNCVSFNQSALILKMLHEHLPG---MPLLVYPNSGEIYNPKEKTWHRPTNKLDDWETTVKKFVDNGARIIGGCCRTSPKDIAEIASAVDKYS---------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "Q08985-1", "uniprot_id": "SAM4_YEAST", "id": "Q08985-1", "name": "Homocysteine S-methyltransferase 2", "aln": "-----MARLPLKQFLADNPKKVLVLDGGQGTELENRGIKVAN--PVWSTIPFISESFWSDESSANRKIVKEMFNDFLNAGAEILMTTTYQTSYK--------------SVSENTPIRTLSEYNNLLNRIVDFSRNCIGEDKYLIGCIGPWGAHIC--REFTGDYGAEPENIDFYQYFKPQLENFNKNDKLDLIGFETIPNIHELKAILSWDES---ILSRPFYIGLSVHEHGVLRDGTTMEEIAQVIKDLG--DKINPNFSFLGINCVSFNQSPDILESLHQALPN---MALLAYPNSGEVYDTEKKIWLPNSDKLNSWDTVVKQYISSGARIIGGCCRTSPKDIQEISAAVKKYT---------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "Q9VJ32-1", "uniprot_id": "Q9VJ32_DROME", "id": "Q9VJ32-1", "name": "Hcy-binding domain-containing protein", "aln": "--------MGLTR--------VLVKDGGFGTQMTVHVGDSVDGDPLWSAR----------FNATNPAAIISTHLDFLQNGADIILTNTYQSSVDGYMEYLELDEEQSIELIKNTVRLAHIAKERYLTECYQAQLSVQEGYPLIIASIGPFGAHLHDGSEYTGSYADFVPAKEITDWHRVRIEACLEAG-VDALAIETIPCQMEAEALVEMLCDD--YPDVKFWVAFQCKDENTLAHGETFADAANAIWDLLAERNAQDKCLAIGVNCVHPKFVTPLFKSLNGDREVGEQIPLVVYPNSGEVYDVVNG-WQGR-EHCVPLANYVPEWAQLGAKVIGGCCRTYARDIRHIGEAIRDWNKLKKLS---------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VJ31-1", "uniprot_id": "BHMT_DROME", "id": "Q9VJ31-1", "name": "Betaine-homocysteine S-methyltransferase", "aln": "--------MEVNQKWNWDTKPILVKCGGFSSQLAKNVTEKVDGDPLWGSR----------FDATNPEAVIQTHLDFLRNGADIILTNTYQSSVEGFVKYLGVTRERGVELIQKSVQLAKQAKEQYLSEIGS---EAESALPLIMGSIGPYGAYLHDGSEYTGNYADKMSKEELRAWHKTRIEICLAAG-VDGLALETLPCLMEAEAVTELVLDN--FPDAKFWVSLQCMDEKHMASGENFAEAALSLWRLVQSRKAENRLLGIGLNCVNPLFVTPLLSSLT-KVAGSDRIPLVVYSNRGEIYDVEQGDWTG---TGEEVVKFVPEWIQLGVRIVGGCCRVYPTDVLAIRKYVDGLN-IKP-----------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ::: .. : . . * . : . . :*: *:::: * *: : . . : . . * : * * .: :: :* : * : * . : :. . . . : . : : :. . . :: : . : . * : :**** . .: : : ", "identical_positions": 16, "similar_positions": 61, "identity": "3.61%" }, { "cls_id": "homologset.agr.MGI:1891384", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZH42-1", "uniprot_id": "D3ZH42_RAT", "id": "D3ZH42-1", "name": "RNA helicase Mov10l1", "aln": "MLRLAAKLVSFFWRREDIPEEEVGQPRQELSEGDTRLKTVQGVVTRYCSDYGMIDDLIYFSNDAVTSKVLLNVGQEVIAVVEENKVSNGLKAIRVEAVSDKWEDDNRNSSKGLSDSSPRVLIGCVTSMLEGAGYISQTTYFSLESVCEGFHPCKGDWVEAEYWIRPGTWSSEAISVKPLRYKRVDKVCISSLCGRNGVIEDSIFFSLDSLKLPEGYTPRRHDIVNAVVVESSQSCYIWRALCMTPVKR-EAIIGEAPQEPYGALLLKNKGDVEVTRTTSFGTLKEGESKAVVIWIENKGEISQDLVSCRLAGWDKAHQFRFEAQGRGQACAGVAAVAVSE-----GENVNSLNHHREDKPDPIPESSLENNTEISPDGCACTEESREKGDTAEKQ---EPEPGGLIPPGEKTSIVVTCNAKNPGRCKELLLLCFSNFLIGRHLEVNVVS-------------SEEALIAVREPFSWKKPKSSQTIVSAKTTVVVTTQKRNSRRQLPSFLPQYPIPDRLKKCVEQK-------IDILTFQPLLAELLNMSNYKEKFSTLLWLEEIHAEIELKEYNMSGVVLKRKGELLVLEVPGLAESRPSLYAGDKLILK---SQEYNGHVIEYIGYVMEIHEEDVTLKLNPGFEQMYNFEPMDVEFTYNRTTSRRCHYALEQVI-HLGVKVLFPEEIILQSPQVTGNWSLAQDTKSDGQSITKVTRNDGQSITNITKNDGQSITNITKNDGQSITKVTKNDGQSITNITKNDGQSITSITKNGGQSINKVTRNDGQSITNITRNDGQSITKVTKNGGQSISKVTRNDGQSITKNKKTVKDQTKNTTKERHLSTTDQPEKTASTAET---MDEIQIPRARDKEFFNPVLNENQKLAVRRILSGDCRPLPYILFGPPGTGKTVTIIEAVLQVHYALPDSRILVCAPSNSAADLVCLRLHESKVLKPAAMVRVNATCRFEETIIE-AIKPYCRDGED----------------------IWRASRFRIIITTCSSAGLFYQIGVRVGYFTHVFVDEAGQASEPECLIPLGLISDINGQIVLAGDPMQLGPVIKSRLAMAYGLNVSMLERLMSRPAYLRDENAFGACGAYNPLLVTKLVKNYRSHSALLALPSRLFYHRELEVCADP---------KVVTSLLGWEKLPRKGFPLIFHGVRGNEAREGRSPSWFSPAEAVQVMRYCCLLARNVSSQVSSKDIGVITPYRKQVEKIKILLRNVDLTDIKVGSVEEFQGQEYLVIVISTVRSNEDRFE-DDRYFLGFLSNSKRFNVAITRPKALLIVLGNPHVLVRDPCFGALLEYSVTNGVYTGCDLPPELQALQK--------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q99MV5-1", "uniprot_id": "M10L1_MOUSE", "id": "Q99MV5-1", "name": "RNA helicase Mov10l1", "aln": "----------------------------------------------------MIDDLIYFSNDAVTSTVLLNVGQEVIAVVEENKVSNGLKAIRVEAVSDKWEDDSKNSSKGLSDSSPRVLIGCVTSMLEGAGYISQTTYFSLESVCEGFHPCKGDWVEAEYWIRPGTWSSEAISVKPLRYKRVDKVCISSLCGRNGVIEDSIFFSLDSLKLPEGYIPRRHDIVNAVVVESSQSCYIWRALCMTPVKR-DATLGEAPQEPYGALLLKNKGDIEVTRMTSFGTLKEGESKSIVIWIENKGKFSRELVSCRLANWDKAHQFRFETQGRSKSCPGAAAGSVPE-----GENVNSLNHHREDKTDEIPESRLANSTEISPDGCACKEESREKGNTPEKQ---EPEPGGLIPPGEKTHIVVTCSAKNPGRCKELLLLCFSDFLIGRHLEVSVVS-------------SEEALIAVREPFSWKKPKSSQTLVSAKTTVVVTTQKRNSRRQLPSFLPQYPIPDRLKKCVEQK-------IDILTFQPLLAELLNMSNYKEKFSTLLWLEEIHAEIELKEYNMSRVVLKRKGDLLVLEVPGLAESRPSLYAGDKLILK---SQEYNGHVIEYIGYVMEIHEEDVTLKLNPGFEQMYNFEPMDVEFTYNRTTSRRCHYALEQVI-HLGVKVLFPEEIILQSPQVTGNWSLAQDTK----------------------NDGQSITNITRNDGQSMTKVTRNDSQSITNIIRNDGQ----------------------SITNVTRNDGQPITKVTRNNSQSITNITRNDGQPITKNKKTVKDQTKHTTEERHVGTTDQPEKASSTAET---MDEIQIPKARDKEFFNPVLNENQKLAVRRILSGDCRPLPYILFGPPGTGKTVTIIEAVLQVHYALPDSRILVCAPSNSAADLVCLRLHESKVPKPAAMVRVNATCRFEETIID-AIKPYCRDGED----------------------IWRASRFRIIITTCSSAGLFYQIGVRVGYFTHVFVDEAGQASEPECLIPLGLISDINGQIVLAGDPMQLGPVIKSRLAMAYGLNVSMLERLMSRPAYLRDENAFGACGAYNPLLVTKLVKNYRSHSALLALPSRLFYHRELEVCADP---------KVVTSLLGWEKLPRKGFPLIFHGVRGNEAREGRSPSWFSPAEAVQVMRYCCLLARSVSSQVSSKDIGVITPYRKQVEKIKILLRNVDLTDIKVGSVEEFQGQEYLVIVISTVRSNEDRFE-DDRYFLGFLSNSKRFNVAITRPKALLIILGNPHVLVRDPCFGALLEYSVSNGVYTGCDLPPELQALQK--------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9BXT6-1", "uniprot_id": "M10L1_HUMAN", "id": "Q9BXT6-1", "name": "RNA helicase Mov10l1", "aln": "MLSLAAKLVAFFWRTADTPREEAGQLEPELAEGDTKLKTVRGVVTRYCSDYGMIDDMIYFSSDAVTSRVLLNVGQEVIAVVEENKVSNGLKAIRVEAVSDKWEDDSRNHG-SPSDCGPRVLIGCVTSLVEGAGCISQTTYFSLESVCEGFEPCKGDWVEAEYRIRPGTWSSEATSVKPLRYKRVDKVCISSLCGRNGVLEESIFFTLDSLKLPDGYTPRRGDVVNAVVVESSQSCYVWRALCMTLVKRRDAAPVHEATHFYGTILLKNKGDIEVTQVTHFGTLKEGRSKTMVIWIENKGDIPQNLVSCKLAGWDKSKQFRFQMLDKDQMCPVVSFVSVPEKENSSDENINSLNSHTKNKTSQMSESSLVNNRGISPGDCTCKGENGEKDNILSRKQMTEPEPGGLVPPGGKTFIVVICDGKNPGRCKELLLLCFSDFLIGRYLEVNVIS-------------GEESLIAAREPFSWKKLKSSQALTSAKTTVVVTAQKRNSRRQLPSFLPQYPIPDRLRKCVEQK-------IDILTFQPLLAELLNMSNYKEKFSTLLWLEEIYAEMELKEYNMSGIILRRNGDLLVLEVPGLAEGRPSLYAGDKLILK---TQEYNGHAIEYISYVTEIHEEDVTLKINPEFEQAYNFEPMDVEFTYNRTTSRRCHFALEHVI-HLGVKVLFPEEIILQSPQVTGNWNHAQDTK---------------------------------SSGQSTS----------------------------------------------------------------------------KKNRKTMTDQAEHGTEERRVGDKDLPVLAPFTAEMSDWVDEIQTPKARKMEFFNPVLNENQKLAVKRILSGDCRPLPYILFGPPGTGKTVTIIEAVLQVHFALPDSRILVCAPSNSAADLVCLRLHESKVLQPATMVRVNATCRFEEIVID-AVKPYCRDGED----------------------IWKASRFRIIITTCSSSGLFYQIGVRVGHFTHVFVDEAGQASEPECLIPLGLMSDISGQIVLAGDPMQLGPVIKSRLAMAYGLNVSFLERLMSRPAYQRDENAFGACGAHNPLLVTKLVKNYRSHEALLMLPSRLFYHRELEVCADP---------TVVTSLLGWEKLPKKGFPLIFHGVRGSEAREGKSPSWFNPAEAVQVLRYCCLLAHSISSQVSASDIGVITPYRKQVEKIRILLRNVDLMDIKVGSVEEFQGQEYLVIIISTVRSNEDRFE-DDRYFLGFLSNSKRFNVAITRPKALLIVLGNPHVLVRDPCFGALLEYSITNGVYMGCDLPPALQSLQNCGEGVADPSYPVVPESTGPEKHQEPS", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6J5K9-1", "uniprot_id": "ARMI_DROME", "id": "Q6J5K9-1", "name": "5'-3' RNA helicase armi", "aln": "---MFTYVSKFFTNPDRNREDILESLDRENSFLDQKLMEEKMDQQLKANPNEINGVLSNKIAELTHGLSEMDVSKESSCTARKGVITS------LDGDRGVIDKDVLFETKVAEDIILDLHVGCVVEYLT----FTTGEAMRVVKVKSILEHSWEDTSQKEIEKAVDNLKNEKPTFFNTETRSVLGLISQRLASSIDVETEYGQLTVELDNIEMNFIPTNGDRVRLECNIQLDDGFVDKQGEILEVTKLFPTRIQEGEK---CIVERVYVHMVVLGPETY-ILKTDLPTGTDLHLG--DIVLADLIECQYSKFTR-RAIKITPLEKNFGATKLTQQSSMG-SSGSGKAVTVTGVNRFITAELWQKESVSLKLTNNLNRTLRLESITVCNDSESQLSVVSPLESKEISSGSEITVTFEIHTQFLGEAIEKYVLNFDLLKVRRVFTVIVCKTKEEVAEAEKRMIAAEALMAPGRNSQERSRFYANQVWCNKVDVIPGQQIVTKRRFVALRLGCFEVPKELRQICLTSERRQEMIKAIEQHYSFLTEPLSIKTYMHRFRLLLHLEEIECFVNFRNYDRDRAHFLRDGEFLTLQIENLAERRPSLVIGDTLRVINPWSDPDSQTTKSYEGIIHKVLFDRILLKFHSSFQEKYNGEDYRLEFYFSRYSFRKQHHAISKIVGVMGEDFLFPSKVTKR----------------------------------------------------------------------------------------------------------------------------------------------ENPQLDVYMKDDD------------------MYLYDSKLEWYNQSLNSIQKRAVFNILRGEAENIPYVLFGPPGSGKTMTLIETLLQLVRNLPGARILVGTPSNSSADLVTKRLIDSKALLQGDFIRLVSYNQVEKDLIPPEIMSYCATSDVGAVGSCEDKMMVTESGLKLRCQAKFIGTHRITISTCTTLGNFLQLGFPAGHFTHVLFDEAGQCTEPETMVPIVMLTKKRSQVVLSGDPRQLQSIVTSRIASKMGFSISFLERLLERSPYRKDLQRFPESSGYNPLVLTKLLYNYRALPSIMSIYSRLFYDDELIPVLSEKDSRESRLLSKLRCVFESEKDIPQAHGTFFYGIIGENRQNNDSPSWFNPQEVREVFLMTIALYR---ANVTADQIGIITPYQKQVKMLRSMFIGTDVVMPKIGSVEEFQGQERDIILISTVRSSEEILRMDARFSLGFVRCSKRLNVAVSRARAMMIIFGNPHLLAVDECWRQLILFCVKNNAYFGCDLPQMVINQKDEVPVCLETFVPSLNTTDDLN------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . : : . . ::*.:* ....:. ::. ::. . :.* .* : :***.. : :: : : .* . :. . * : * .. ..* :. . : * : . *.. .* : :::: :: .: * . * *. . :. :: : : *.: . . . :: : .: * : ** . .. : : . . :*:.*: : : : : ::: :. .. : : .: :. . : ... :. : . . . . .: .: .* . :..* : :.. : *.. * :* *. : : * : * * . . *:*:* . . :. :: : . *. *: * ..** :. * : :*..*:: . * . .:*:* *.:..* .:* ** **** . :::::*: . : *.*::*.*:: .*** **** **.* : :: . . .* . : :: : : **::. *:: ** * :** :.* : *: *.*:.::: :* ..***.:: : :: : : * . *::* **. ** ** .** *:.. :**:******:***:*:**::**: **.:**** :****:**** ** :**. . ::*: : :.*: :* : .** .: . .** *:**:: * * *:*. .*:****:.*****.:*** ::*: :::. .*:**:*** ** .::.**:* *:.:*:****:.*..* :* : * ...:***::***: ***: ::: : *****. ** . . : .:: ** :.. :*:*: *.: ::. *****.* *. :*: * : ::*::.:**:****:***: :: :: ..*: *:********** :*:******.*: :. * *: ***: ***:***::*.:*::*::****:*. * *: *: :.:.*..* ***** : :. ", "identical_positions": 271, "similar_positions": 390, "identity": "19.67%" }, { "cls_id": "homologset.agr.MGI:1891393", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9Z0K5-1", "uniprot_id": "IGSF6_RAT", "id": "Q9Z0K5-1", "name": "Immunoglobulin superfamily member 6", "aln": "MGPVSTSRRGLRLGISLILLQVGVVGACTVSVLQPGYLEVDYTSQTVTMECTFSTTGCPAVQPKSLWFRCGTHQPEALCLDGCRNEADKFTVKETLDQNRVSLTVNRLSPNDSAIYICGIAFPNEPVPTAKQTGDGTTLVVRER-LFSREVHSLLIVLLALLAVYVTGVCVIFIVLFRSKSNTPRSRETKEDSKKK-SARRIFQEIAQELYHKRYVETSHQPEQDG-NYENRKALPSPGRP", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P0C6B7-1", "uniprot_id": "IGSF6_MOUSE", "id": "P0C6B7-1", "name": "Immunoglobulin superfamily member 6", "aln": "MGPVSARRSRLRPEISLILFQVGMVGACTVYVLQPGYLEVDYGSDAVTMECNFSTVGCPPVPPKSLWFRCGTHQPEALCLDGCRNEADKFTVKETLDPDQVFLTVNRLSPNDSAIYICGIAFPNELSPSAKHVGKGTTLVVRER-LFSKEVRSFLIVLLALLSVYITGVCVTFIVLFKSKSNGPRSRETK-GSKKK-SARRIFQEIAQELYHKRYVETSHLPEQEG-TDENRKALPNPGRA", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O95976-1", "uniprot_id": "IGSF6_HUMAN", "id": "O95976-1", "name": "Immunoglobulin superfamily member 6", "aln": "MGTASRSNIARHLQTNLILFCVGAVGACTLSVTQPWYLEVDYTHEAVTIKCTFSATGCPSEQPTCLWFRYGAHQPENLCLDGCKSEADKFTVREALKENQVSLTVNRVTSNDSAIYICGIAFPSVPEARAKQTGGGTTLVVREIKLLSKELRSFLTALVSLLSVYVTGVCVAFILLSKSKSNPLRNKEIKEDSQKKKSARRIFQEIAQELYHKRHVETNQQSEKDNNTYENRRVLSNYERP", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "**..* . : .***: ** *****: * ** ****** ::**::*.**:.***. *..**** *:**** ******:.*******:*:*. ::* *****::.*************. . **:.* ******** *:*:*::*:* .*::**:**:***** **:* :**** *.:* * .*:** *****************:***.: .*::. . ***:.*.. *.", "identical_positions": 139, "similar_positions": 61, "identity": "57.68%" }, { "cls_id": "homologset.agr.MGI:1891396", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q6X936-1", "uniprot_id": "KIRR1_RAT", "id": "Q6X936-1", "name": "Kin of IRRE-like protein 1", "aln": "MTLENRSTCLMTCQSSLLPKKPRFLSQKMWAPHLVVAYLIFVTLALAL-----------------------------------PGTQTRFSQEPADQTVVAGHRAVLPCVLLNYSGIVQWTKDGLALGMGQGLKAWPRYRVVGSADAGQYNLEITDAELSDDASYECQAT-----EAALRSRRAKLTVLIPPEDTRIDGGPVILLQAGTPYNLTCRAFNAKPAATIIWFR--DGTQQEGAVTSTELLKDGKRETTISQLLIQPTDLDIGRVFTCRSMNEAIPNGKETSIELDVHHPPTVTLSIEPQ-----------------------TVLEGERVIFTCQATANPEILGYRWAKGG-FLIEDAHESRYETNVDYSFFTEPVSCEVYNKVGSTNVSTLVNVHFAPRIVVYPKPTTTDIGSDVTLTCVWVGNPPLTLTWTKKDSNMVLSNSNQLLLKSVTQADAGTYTCRAIVPRIGVAEREVPLYVNGPPIISSEAVQFAVRGDGGKVECFIGSTPPPDRIAWAWKENFLEVG---TLERYTVERTNS---GSGVLSTLTINNVMEADFQTHYNCTAWNSFGPGTAIIQLEER-----EVLPVGIIAGATIGAGILLVFSFAALVFFLYRRRKGSRKDVTLRKLDIKVETVNREPLTMHSDREDDTTSISTATRVMKAIYS-------------------SFKDDVDLKQDLHCDTIETR-EEYEMKDPTNGYYNVRAHED---RPSSRAVLYADYRAPG----------------------------------PTRFDGRPSSRLSHSSGYAQLNTYSRAPASDYGTEPTPSGPSAPGGTDTTSQLSYEN--------YEKFNSHPFPGAAGYPTYRLGYPQAPPSGLERTP-YEAYDP------------------------------------------------------------------------------------------IGKYATATRFSYTSQHSDYGQRFQQRMQTHV", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q80W68-1", "uniprot_id": "KIRR1_MOUSE", "id": "Q80W68-1", "name": "Kin of IRRE-like protein 1", "aln": "MTLESPSTRLMTCQSSLLPEKPRFLSQKMWAPHLVVAYLIFVTLALAL-----------------------------------PGTQTRFSQEPADQTVVAGQRAVLPCVLLNYSGIVQWTKDGLALGMGQGLKAWPRYRVVGSADAGQYNLEITDAELSDDASYECQAT-----EAALRSRRAKLTVLIPPEETRIDGGPVILLQAGTPYNLTCRAFNAKPAATIIWFR--DGTQQEGAVTSTELLKDGKRETTISQLLIEPTDLDIGRVFTCRSMNEAIPNGKETSIELDVHHPPTVTLSIEPQ-----------------------TVLEGERVIFTCQATANPEILGYRWAKGG-FLIEDAHESRYETNVDYSFFTEPVSCEVYNKVGSTNVSTLVNVHFAPRIVVYPKPTTTDIGSDVTLTCVWVGNPPLTLTWTKKDSNMVLSNSNQLLLKSVTQADAGTYTCRAIVPRIGVAEREVPLYVNGPPIISSEAVQFAVRGDGGKVECFIGSTPPPDRIAWAWKENFLEVG---TLERYTVERTNS---GSGVLSTLTINNVMEADFQTHYNCTAWNSFGPGTAIIQLEER-----EVLPVGIIAGATIGAGILVVFSFAALVFFLYRRRKGSRKDVTLRKLDIKVETVNREPLTMHSDREDDTASISTATRVMKAIYS-------------------SFKDDVDLKQDLRCDTIDTR-EEYEMKDPTNGYYNVRAHED---RPSSRAVLYADYRAPG----------------------------------PTRFDGRPSSRLSHSSGYAQLNTYSRAPASDYGTEPTPSGPSAPGGTDTTSQLSYEN--------YEKFNSHPFPGAAGYPTYRLGYPQAPPSGLERTP-YEAYDP------------------------------------------------------------------------------------------IGKYATATRFSYTSQHSDYGQRFQQRMQTHV", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q96J84-1", "uniprot_id": "KIRR1_HUMAN", "id": "Q96J84-1", "name": "Kin of IRRE-like protein 1", "aln": "-----------------------MLSLLVWILTLSDTFS--------------------------------------------QGTQTRFSQEPADQTVVAGQRAVLPCVLLNYSGIVQWTKDGLALGMGQGLKAWPRYRVVGSADAGQYNLEITDAELSDDASYECQAT-----EAALRSRRAKLTVLIPPEDTRIDGGPVILLQAGTPHNLTCRAFNAKPAATIIWFR--DGTQQEGAVASTELLKDGKRETTVSQLLINPTDLDIGRVFTCRSMNEAIPSGKETSIELDVHHPPTVTLSIEPQ-----------------------TVQEGERVVFTCQATANPEILGYRWAKGG-FLIEDAHESRYETNVDYSFFTEPVSCEVHNKVGSTNVSTLVNVHFAPRIVVDPKPTTTDIGSDVTLTCVWVGNPPLTLTWTKKDSNMVLSNSNQLLLKSVTQADAGTYTCRAIVPRIGVAEREVPLYVNGPPIISSEAVQYAVRGDGGKVECFIGSTPPPDRIAWAWKENFLEVG---TLERYTVERTNS---GSGVLSTLTINNVMEADFQTHYNCTAWNSFGPGTAIIQLEER-----EVLPVGIIAGATIGASILLIFFFIALVFFLYRRRKGSRKDVTLRKLDIKVETVNREPLTMHSDREDDTASVSTATRVMKAIYS-------------------SFKDDVDLKQDLRCDTIDTR-EEYEMKDPTNGYYNVRAHED---RPSSRAVLYADYRAPG----------------------------------PARFDGRPSSRLSHSSGYAQLNTYSRGPASDYGPEPTPPGPAAPAGTDTTSQLSYEN--------YEKFNSHPFPGAAGYPTYRLGYPQAPPSGLERTP-YEAYDP------------------------------------------------------------------------------------------IGKYATATRFSYTSQHSDYGQRFQQRMQTHV", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AB13A6Z9-1", "uniprot_id": "A0AB13A6Z9_DANRE", "id": "A0AB13A6Z9-1", "name": "Kin of IRRE-like protein 1", "aln": "-----------------------MQGLLLLLSLALSFHR--------------------------------------------VRT-ARFSQEPADQSVVLGQRVVLSCVVFNYSGIVQWTKDGLALGIGEDLRAWPRYRVLRLVDVGQYNLEISAAELSDDSLYECQAT-----EAALRSRRAKLTVLIPPDEPVIEGSPEILLTAGVPYNMSCVSRGAKPASVIEWQK--DGLPIEGAVSTTEVLPDRKRVTTRSYLPIQPLDTDTGKNFTCVATNLAVPMGKRATITLNVHHPPVVTLSIEPR-----------------------SVLEGERVTFTCQATANPPIMGYKWAKGG-VVIQGARESVFVTKADHSFFTEPVSCQVFNAVGSTNVSILVDVHFGPILVVEPKPVTVDVDSDVTLNCKWAGNPPLTLTWTKKGSSMVLSNNNQLYLKSVSQADAGQYVCKAIVPRIGVGETEVTLTVNGPPIISSEPFQYAVRGERGEVKCYIASTPPPDKIVWAWKENVWEKEKGTLSERYTVEQSKPSAQGGAVLSTLTINNIMESDFQSTYNCTAWNSFGSGTMIISLEEM-----EIVPVGIIAGGTVGCSILLLLCLLALVLFLYRQRKGSRRGVTLGKPDIKVETINKESHSLEEDS----GSVSTATRMVKAMYSFLPSVTLSP-------SSQPFKDDIDLKQELRSDTLDTR-QDYELKDPTNGYYNVRASTHDEGRPASRSMHYSDYRTSSQPGGAAAVVSSSSGPPPGATAGPGTPSSLAPGSRAGCYDPRPPSRLSHNS-YAQFNTFTR--AGQSQQPPPGSGPQTSDFPAECSLLDSSG--------QLGYENYGYP--SHYPTFRMGFAPPSLAPLEGGPAYEMYGVGPSVGAGGG--------------------------------------------------------------------------AGTPETGLGKYGSSTRFSYTSQHSDYSHRHTQRMQTHV", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8M6Z878-1", "uniprot_id": "A0A8M6Z878_DANRE", "id": "A0A8M6Z878-1", "name": "Kin of IRRE-like protein 1", "aln": "-------------------MGFSMTCLWIVTLAIISVHR--------------------------------------------VFSGPRFSQEPADQSVVIGERVVLSCVVFNYTGIVQWTKDGLALGIGEDLRAWPRYRVLRIMDVGQYNLEITSADLTDDSLYECQAT-----EAALRSRRAKLTVLIPPDGPVIEGSPEILLTAGTSFNLTCVSRGAKPMSTIEWYK--DGIIVEGAHTSTEVLSDRKRVTTKSFLEIQPMDTDTGRNFTCVASNLAAPLGKRSTVTLNIHHPPTVILSIEPR-----------------------SVLEGERVKFTCQATANPPIMGYRWAKGG-VILDGARESVFETTADHSFFTEPVSCLVFNAVGSTNVSILVDVHFGPILVVEPRPVTVDVDSDVTLNCKWSGNPPLTLTWTKKGSSMVLSNSNQLFLKSVSQADAGQYVCKAIVPRIGVGETEVTLTVNGPPIISSEPIQYAVRGEKGEIKCYIASTPPPDKIVWAWKENVWEKERGTLLERYTVEQSRPATQGGAVLSTLTINNVMEADFQSTYNCTAWNAFGPGTMIITLEETDIASEDIVPVGVIAGGSVGSSILLLLLLFALIFYLYRQRKSSRRGVTL-KPDIKVETVNKETN-LEEEA----ASASTATRMVKAMYSFLPSVSLSP-------STQPFKDDMDLKQDLQTETLEPKVEEYEAKDPTNGYYNVRATTHDEVRSSTRSLLYQEFRAPN-----PASVSASTGGPANIHPAP-----------TGRYEARPTSRMAHNT-YAHFNTIAR--ASQ-IQPPANPVSKTTDYPAERGLLESTN--------PLAFDSYAY---STTPQYRLGFAP----PLEAGPAYEMYPTGQGVGT-------------------------------------------------------------------------------SQDANVGKYPSSAQFPYSTPPTEYSQRHTQRMQTHV", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q08180-1", "uniprot_id": "ICCR_DROME", "id": "Q08180-1", "name": "Irregular chiasm C-roughest protein", "aln": "--------------------MLHTMQLLLLATIVGMVRSSPYTSYQN----------------------------------------QRFAMEPQDQTAVVGARVTLPCRVINKQGTLQWTKDDFGLGTSRDLSGFERYAMVGSDEEGDYSLDIYPVMLDDDARYQCQVSPGPEGQPAIRSTFAGLTVLVPPEAPKITQGDVIYATEDRKVEIECVSVGGKPAAEITWIDGLGNVLTDNIEYTVIPLPDQRRFTAKSVLRLTPKKEHHNTNFSCQAQNTADRTYRSAKIRVEVKYAPKVKVNVMGSLPGGAGGSVGGAGGGSVHMSTGSRIVEHSQVRLECRADANPSDVRYRWFINDEPIIGGQKTEMVIRNVTRKFHDAIVKCEVQNSVGKSEDSETLDISYAPSFRQRPQSMEADVGSVVSLTCEVDSNPQPEIVWIQHPSDRVVGTSTNLTFS-VSNETAGRYYCKANVPGYAEISADAYVYLKGSPAIGSQRTQYGLVGDTARIECFASSVPRARHVSWTFNGQEISSESGHD--YSILVDAVP----GGVKSTLIIRDSQAYHYG-KYNCTVVNDYGNDVAEIQLQAKKS----VSLLMTIVGGISVVAFLLVLTILVVVYIKCKKRTKLPPADVISEHQITKN--GGVSCKLEPGDRTSNYSD-----LKVDISGGYVPYGDYS-----THYSPPPQYLTTCSTKSNGSSTIMQNNHQNQLQLQQQQQQSHHQHHTQTTTLPMTFLTNSSGGSL---------------------------------TGSIIGSREI-RQDNGLPSLQSTTASVVSSSPNGSCSNQSTTAATTTTTHVVVPSS----------MALSVDPRYSAIYGNPYLRSSNSSL--LPPPTAV--------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9W4T9-1", "uniprot_id": "Q9W4T9_DROME", "id": "Q9W4T9-1", "name": "", "aln": "------MKRMRSSRLLVLPLILVLILTLLLQPIAVHAKSKKNKSSQSSHHGDSSSSSSSSSSSSGSSSAAASSANDESKPKGGDNGGQHFAMEPQDQTAVVGSRVTLPCRVMEKVGALQWTKDDFGLGQHRNLSGFERYSMVGSDEEGDFSLDIYPLMLDDDAKYQCQVGPGPQGEQGIRSRFAKLTVLVPPEAPKITQGDYLVTTEDREIELECVSQGGKPAAEITWIDGLGNVLTKGIEYVKEPLADSRRITARSILKLAPKKEHHNTTFTCQAQNTADRTYRSAKLLLEVKYAPKVIVSVVG----------GALAGG--------KIPEGAEVILSCQADANPHELSYRWFINDELMTGDFTTKMIIHNVSRQYHDAIVKCEVVNAVGKSEQSKKLDISFGPVFRQRPVSVEADLGATVSMRCDVAGNPEPEIEWISENSDQVVGVAAELKLK-VSSETAGRYFCKAVVNGFPEIGAEATLYVKRAPIITSHKVQFGGVGGRVKIDCLAFSIPKAEHILWSFEGKIINMSSADPDIYIFEEHHLP----EGVRAALIIRDSKATHFG-KYNCTVMNSYGGDSLVITLLREPGN---IPVLLVVMGSMFCVAIILMIVMIIIVYRKRRSRKKPMPADVIPEASRGGDKLNELKSELRSKAYDVEYSEAGGDGLAINLTQSPMPDVQMKGATLGVPLAGPVKFDERFSGDFGGDRYNRQCHIKNLKNQQETAYKGSPQANGYAHYFEYALDYSPPGGEG---------------------------------AAVVVGSGGVGKLKNGGMNSATLPHSAAATVNGGGAGNGGGASLPRNQRHEIQQSQQSNGFLGQPLLQNGIDSRFSAIYGNPYLRTNSSLLPPLPPPSTANPAATPAPPPYHAARHGHAHHANGGLKHFVGGAVITTSPVGNVNINGGGGGGSTPSGGGGVGVGVAAGGSVSGSSSNLTASSNTLAATPLAGGGVGNSGQCAQSPSGQFILSNNGKGHTQKGPLATHV", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : :*: ** **:.* * *..*.* ::: * :*****.:.** ..* .: ** :: : *::.*:* * **: *:**. : .:** * ****:**: . * . : . :: * : ..** : * * .. .. * * :* *: * * : * . . . *:* : * * : :.: :::::.* * :.: : * .* : *:* *** : *:* .. : . . .. .:. *.* * * **.:: * ::: :.* : * . .*:.: *:: * .** : * .. *. *:. :* :. *:. ** * *:* * :. : :: .* * *. *:. * .:.* * * . :: *::: : . . .* ::* *.: .: ****. * :* . * * : : : *. .::::: : :: : *. .: : . : . :. * : : . : . . . : . : : : : . :. : :. . : : . . . . : * * . . ", "identical_positions": 117, "similar_positions": 198, "identity": "11.45%" }, { "cls_id": "homologset.agr.MGI:1891408", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A0G2KA21-1", "uniprot_id": "A0A0G2KA21_RAT", "id": "A0A0G2KA21-1", "name": "", "aln": "-------------------MKAAYTAYRCLTKDLEGCAMNP----ELTMESLGTLHGPVGGGSGGGGGGGGGGGGGGPGHEQELLASPSPHHAGRGAAGSLRGPPPP-----------------------------------------------------TAHQELGTAAAAAAAAS--RSAMVTSMASILDGS-------DYRPELS----------IPLHHAMSMSCD-------------------------SSPPGMGMSN------------------------------------------------------------------------TYTTLTPLQPLPPISTVSDKFHHPHPHHHPHHHHHHHHHHQR-----------------------LSGNVSG--------------SFTLMRDERGLPSMNNLYSPY---KEMPSMS--QSLSPLAATPLGNGLGG--LHNAQQSLPNYGPPG----HDKMLSPN----FDAHHTAMLTRGE-----------------------------------QHLSRG--------------------------------------------LGTPPAA--MMSHLN------------------------------------------------GLH-------------------------------------------HPGHTQSHGPVLAPSRERPPSSSSGSQ-------------VATSGQLEEINTKEVAQRITAELKRYSIPQAIFAQRVLCRSQGTLSDLLRNPKPWSKLKSGRETFRRMWKWLQEPEFQRMSALRLAG---------------------------------------------------------------------QVYQSPRKAGPSSQPMNLPSLSTVK----LGYTAKTTPPDQVSEVRIVPK-----------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q6XBJ3-1", "uniprot_id": "ONEC2_MOUSE", "id": "Q6XBJ3-1", "name": "One cut domain family member 2", "aln": "-------------------MKAAYTAYRCLTKDLEGCAMNP----ELTMESLGTLHGPVGGGSGGGGGGGGGGGGGGPGHEQELLASPSPHHAGRGAAGSLRGPPPP-----------------------------------------------------TAHQELGTAAAAAAAAS--RSAMVTSMASILDGS-------DYRPELS----------IPLHHAMSMSCD-------------------------SSPPGMGMSN------------------------------------------------------------------------TYTTLTPLQPLPPISTVSDKFHHPHPHHHPHHHHHHHHHHQR-----------------------LSGNVSG--------------SFTLMRDERGLPSMNNLYSPY---KEMPSMS--QSLSPLAATPLGNGLGG--LHNAQQSLPNYGPPG----HDKMLSPN----FDAHHTAMLTRGE-----------------------------------QHLSRG--------------------------------------------LGTPPAA--MMSHLN------------------------------------------------GLH-------------------------------------------HPGHTQSHGPVLAPSRERPPSSSSGSQ-------------VATSGQLEEINTKEVAQRITAELKRYSIPQAIFAQRVLCRSQGTLSDLLRNPKPWSKLKSGRETFRRMWKWLQEPEFQRMSALRLAAC-------------------------------------------------------------------KRKEQEPNKDRNNSQKKSRLVFTDLQRRTLFAIFKENKRPSKEMQITISQQLGLELTTVSNFFMNARRRSLEKWQDDLGTGGSSSTSSTCTKA-----------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O95948-1", "uniprot_id": "ONEC2_HUMAN", "id": "O95948-1", "name": "One cut domain family member 2", "aln": "-------------------MKAAYTAYRCLTKDLEGCAMNP----ELTMESLGTLHGPAGGGSGGGGGGGGGGGGGGPGHEQELLASPSPHHAGRGAAGSLRGPPPPP----------------------------------------------------TAHQELGTAAAAAAAAS--RSAMVTSMASILDGG-------DYRPELS----------IPLHHAMSMSCD-------------------------SSPPGMGMSN------------------------------------------------------------------------TYTTLTPLQPLPPISTVSDKFHHPHPHHHP--HHHHHHHHQR-----------------------LSGNVSG--------------SFTLMRDERGLPAMNNLYSPY---KEMPGMS--QSLSPLAATPLGNGLGG--LHNAQQSLPNYGPPG----HDKMLSPN----FDAHHTAMLTRGE-----------------------------------QHLSRG--------------------------------------------LGTPPAA--MMSHLN------------------------------------------------GLH-------------------------------------------HPGHTQSHGPVLAPSRERPPSSSSGSQ-------------VATSGQLEEINTKEVAQRITAELKRYSIPQAIFAQRVLCRSQGTLSDLLRNPKPWSKLKSGRETFRRMWKWLQEPEFQRMSALRLAAC-------------------------------------------------------------------KRKEQEPNKDRNNSQKKSRLVFTDLQRRTLFAIFKENKRPSKEMQITISQQLGLELTTVSNFFMNARRRSLEKWQDDLSTGGSSSTSSTCTKA-----------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1QUT6-1", "uniprot_id": "A0A8M1QUT6_DANRE", "id": "A0A8M1QUT6-1", "name": "One cut domain family member", "aln": "-------------------MKTAYNAYRCLAKDLDAYAMNP----EMTMD-IGSLH-------------------AGVSHEQDLMSSHSPHHS-RNPGAALR-----------------------------------------------------------IHQDL------SVAPS--RSAMVSSMASILDGGGGGGGGGEYRPELS----------LPLHHAMSMPCD-------------------------TSPP--GMSG------------------------------------------------------------------------TYTTLTPLQPLPPISTVSDKFHHPH--------HHHHHHHQR-----------------------LSGNVSG--------------SFTLMRDERTLPAMNNLYSPYH--KDMSGMG--QSLS-----PLGNGLGS--IHSAQPTLHNYG-------HDKMLSSN----FDAH-TAMLSRGD-----------------------------------QHLSRG--------------------------------------------LGGPAAG--MMPHLN------------------------------------------------GMHA------------------------------------------HPGHPPSHGPVLASNRDRPLSSSSSSCG------------APGSGQLEEINTKEVAQRITAELKRYSIPQAIFAQRVLCRSQGTLSDLLRNPKPWSKLKSGRETFRRMWKWLQEPEFQRMSALRLAAC-------------------------------------------------------------------KRKEQDPSKDRSNTPKKSRLVFTDLQRRTLLAIFKENKRPSKEMQMTISQQLGLELSTVSNFFMNARRRSLDKWLDEGSPNNSSS--STCTKA-----------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9NJB5-1", "uniprot_id": "ONEC_DROME", "id": "Q9NJB5-1", "name": "Homeobox protein onecut", "aln": "MDSLNDIIDHQTFSQELVEDASEFITVGHHSERPSQSSQQPNSGQDLTMSMQDIISCPVKHRTCSASGSGSASGSDSVVMVIDALGQGNRQSAYQIVPQQLQQRNMPLPFGLLERDRQHMQHGREVNTSPVDFVSSDINLDGLTVDADVSQTDHSQETAVKQEQKLLIVQSKSQDQSHRRIRMLVDVSSVNSGLG---VHVDDMDEISSDGVGCDDEGVTLSHQHLLEQEEQFGLTSHHPHLQPHTQIIHGLHQRSTHSEMGLDNGHGEVLSVIVHSQDSDKEDCEENDDGDAEGDLENEDDDERDSRSREQLLSHSSYQTLTSVNDRLSSPGFSQTSYATLTPIQPLPPISTMSEKFAYSGHISGGDSGDTDVNGDGAGGGVVEVGEVTNQSSEATGTVSISSGNATSSVCSNNDCSSFSALSMPIGSGHLGLGVLSGVQSPFSSYEKLSSMISPPPNNYLVSCDLHSSVSGRVINSSHLQLSHNGNKKESGTHEHTHRPADVNGGKFSYTGHISRGDSVDNDVNGEKFSFSDHISGGDSGDEDANREKFIYSDHISEGENGPDVNSGTNWLQMHSEREVRLHMPVPAELEARFHISSERRTRLNVPPARGSLSRHLAPNAPICPADWKADDWKHSNAGVVSLTADMPVVVSLTPTPPPLRDDSVSGIKQNERSSPGHREQYFLDKSQEPSSVVADQCSPGINGTPQSVCVIHQQSPSALGNGFQSSSQQAKVSSCASPKGTVSSGGAVSNRIANSSDMEEINTKDLAQRISAELKRYSIPQAIFAQRVLCRSQGTLSDLLRNPKPWSKLKSGRETFRRMYKWLQEPEFQRMSALRMAAAQIPQRAPLSSGMSLGSATGPSGSTGTIPTDLDPHGGPTMIQNPLTNESDSSPASTPVTSVLVGSVVSCRRKEEPQIEQMPQPKKPRLVFTDLQRRTLQAIFKETKRPSKEMQVTIARQLGLEPTTVGNFFMNARRRSMDKWRDDDSKSTMHVAHSRQQQDEQQKDNAHTHSQSQIQDQNHSQNQAIHNSMSQDPYSNLHTTAMSPLGAFDEDADMDLELESHDFDLVDPDEHGDTNDPNGDML", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : : :: . : :* ::**. . : . : :.. . : : : *: .*.* : * * *: .::*: .* : *:* :.* * : : :: . *:.. :*:****:********:*:** :. . . : . ***.:. *:.: .. * :..: **: :.:..* . . * ..:.. ::.:: * : * *:: . . *. ::**: :*:*.* *. *.* : ** *:: * . : * : .. ::. **..* . *.::******::****:************************************************:***************:*. : :.* :: :: . :.. *.: :: * : ", "identical_positions": 139, "similar_positions": 138, "identity": "12.82%" }, { "cls_id": "homologset.agr.MGI:1891409", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I5ZNY2-1", "uniprot_id": "A0A8I5ZNY2_RAT", "id": "A0A8I5ZNY2-1", "name": "One cut domain family member", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MELSLESLGGLHGVT-HAQAGELLSPGHARSAAAQHRSLVA-SGRPGLVAGMASLLDGGGAGGGG-AGGAGAAGAAGGGPDFRG--ELAGPLHP-------AMGMACEAPG-LGGTYTTLTPLQH-LPPLAAVADKFHQH----AVAGAHGGHPHAHPHPATAPPPPPP-QRLAAS-VSGSFTLMRD---------------------------ERAALASVGHLYGPYGKELPTMGSPLS------------------------------------------------------------------------------------------------------------------------------PLPSALPPALHSAPQPPPPPPP--LAAYGAPGHLAGDKLLPPAAFEP-------------------------------------------------HAALLGRAEDALARGLPGGGGGAGG--GGAAGGAAAGLLAPLGGLATAGAHGPHSGGGGPGGGGGAG-GGSGGPGAGAAAEEINTKEVAQRITAELKRYSIPQAIFAQRILCRSQGTLSDLLRNPKPWSKLKSGRETFRRMWKWLQEPEFQRMSALRLAACKRK-------------------------------------------------------------------EQDQQKERALQPKKQRLVFTDLQRRTLIAIFKENKRPSKEMQAT-----ISQQLGLELNTVSNFFMNARRR---CMNRWAEE--------------------------------------------PGATPG-TATATATFSKA-------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8K557-1", "uniprot_id": "ONEC3_MOUSE", "id": "Q8K557-1", "name": "One cut domain family member 3", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MELSLESLGGLHGVT-HAQAGELLSPGHARSAAAQHRSLVA-SGRPGLVAGMASLLDGGGAGGGG-AGGAGAAGAAGGGPDFRG--ELAGPLHP-------AMGMACEAPG-LGGTYTTLTPLQH-LPPLAAVADKFHQH----AVAGAHGGHPHAHPHPATAPPPPPP-QRLAAS-VSGSFTLMRD---------------------------ERAALASVGHLYGPYGKELPTMGSPLS------------------------------------------------------------------------------------------------------------------------------PLPSALPPALHSAPQPPPPPP---LAAYGAPGHLAGDKLLPPAAFEP-------------------------------------------------HAALLGRAEDALARGLPGGGGGAGG--GGAAGGAAAGLLAPLGGLAAAGAHGPHSGGGGPGGGGGAG-GGSGGPGAGAAAEEINTKEVAQRITAELKRYSIPQAIFAQRILCRSQGTLSDLLRNPKPWSKLKSGRETFRRMWKWLQEPEFQRMSALRLAACKRK-------------------------------------------------------------------EQDQQKERALQPKKQRLVFTDLQRRTLIAIFKENKRPSKEMQAT-----ISQQLGLELNTVSNFFMNARRR---CMNRWAEE--------------------------------------------PGATPG-TGTATATFSKA-------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O60422-1", "uniprot_id": "ONEC3_HUMAN", "id": "O60422-1", "name": "One cut domain family member 3", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MELSLESLGGLHSVA-HAQAGELLSPGHARSAAAQHRGLVA-PGRPGLVAGMASLLDGGGGGGGGGAGGAGGAGSAGGGADFRG--ELAGPLHP-------AMGMACEAPG-LGGTYTTLTPLQH-LPPLAAVADKFHQHAAAAAVAGAHGGHPHAHPHPAAAPPPPPPPQRLAAS-VSGSFTLMRD---------------------------ERAALASVGHLYGPYGKELPAMGSPLS------------------------------------------------------------------------------------------------------------------------------PLPNALPPALHGAPQPPPPPPPPPLAAYGPPGHLAGDKLLPPAAFEP-------------------------------------------------HAALLGRAEDALARGLPGGGGGTGS--GGAGSGSAAGLLAPLGGLAAAGAHGPHGGGGGPGGSG-------GGPSAGAAAEEINTKEVAQRITAELKRYSIPQAIFAQRILCRSQGTLSDLLRNPKPWSKLKSGRETFRRMWKWLQEPEFQRMSALRLAACKRK-------------------------------------------------------------------EQEQQKERALQPKKQRLVFTDLQRRTLIAIFKENKRPSKEMQVT-----ISQQLGLELNTVSNFFMNARRR---CMNRWAEE--------------------------------------------PSTAPGGPAGATATFSKA-------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8N7T7L6-1", "uniprot_id": "A0A8N7T7L6_DANRE", "id": "A0A8N7T7L6-1", "name": "One cut domain family member", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MELTMENIGNLHGVSHSHQTGDLMNSPHAR-QSATHRNLVSSHGRSAMVSSMASILDGAG--------------------EYRTDHSLSGPLHP-------AMTMSCDSSMSLSSTYTTLTPLQHHLPPISNVSDKFHHH-----------PHPHAHHHPAH--------QRLAAGNVSGSFTLMRD---------------------------DRG-LASMSNLYGHYSKDLSGMGPPLS------------------------------------------------------------------------------------------------------------------------------PLSNGLG-SLHNSQQT--------LSAYGPSAHLGNDKMISSGGFES-------------------------------------------------HAAMLGRGEEHLARGLGGHGAGIMSSLNGINHHHHHSHSHSQANGSVLSERDRQAGAGGQGGGS-------------GQVEEINTKEVAQRITAELKRYSIPQAIFAQRILCRSQGTLSDLLRNPKPWSKLKSGRETFRRMWKWLQEPEFQRMSALRLAACKRK-------------------------------------------------------------------EQEQHKERNMAPKKQRLVFTDLQRRTLIAIFKENKRPSKEMQLT-----ISQQLGLELSTVSNFFMNARRR---CVDRWHEEH----------------------------------------HHGHVASPGQPGTSATTFSKA-------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0AC58I1Y3-1", "uniprot_id": "A0AC58I1Y3_DANRE", "id": "A0AC58I1Y3-1", "name": "", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MELTMENIGNMHGVASHGQPGDLMNSSHGRPPSASHRNLVS-HGRSAMVSSMASILEGAG--------------------DYRSDPALSGHLHP-------AMTM-CESGMSLSNTYTTLTPLQH-LPPISTVSDKFHH------------AHPHPHHHAAH--------QRLATGNVSGSFTLMRD---------------------------DRG-LASMGNLYGHYPKEMSGMGQPLS------------------------------------------------------------------------------------------------------------------------------PLSNGLG-SLHNSQQA--------LSAYGPGAHIPNDKMLSPGGFES-------------------------------------------------HAAMLSRSEEHLARSLGGHGHGMISNLNGM---HAHGHLHTPANGSMLADRERHGGGPGQSGGS-------------GQVEEINTKEVAQRITAELKRYSIPQAIFAQRILCRSQGTLSDLLRNPKPWSKLKSGRETFRRMWKWLQEPEFQRMSALRLAGNVQEKGA-------------------------------------------------------------GAAQRQKHGAQEAAAGVHRPTAPNTHRHLQGEQTTQQGDADHHLAAAGPGALHRQQLLHERPAPLRGPLAGRARQQPRTARDFSQH----------------------------------------LFQGVNAEEDASTHVQHMMIYGAHQNSSD-----------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9NJB5-1", "uniprot_id": "ONEC_DROME", "id": "Q9NJB5-1", "name": "Homeobox protein onecut", "aln": "MDSLNDIIDHQTFSQELVEDASEFITVGHHSERPSQSSQQPNSGQDLTMSMQDIISCPVKHRTCSASGSGSASGSDSVVMVIDALGQGNRQSAYQIVPQQLQQRNMPLPFGLLERDRQHMQHGREVNTSPVDFVSSDINLDGLTVDADVSQTDHSQETAVKQEQKLLIVQSKSQDQSHRRIRMLVDVSSVNSGLGVHVDDMDEISSDGVGCDDEGVTLSHQHLLEQEEQFGLTSHHPHLQPHTQIIHGLHQRSTHSEMGLDNGHGEVLSVIVHSQDSDKEDCEENDDGDAEGDLENEDDDERDSRSREQLLSHSSYQTLTSVNDRLSSPGFSQTSYATLTPIQP-LPPISTMSEKFAYSG---HISGGDSGDTDVNGDGAGGGVVEVGEVTNQSSEATGTVSISSGNATSSVCSNNDCSSFSALSMPIGSGHLGLGVLSGVQSPFSSYEKLSSMISPPPNNYLVSCDLHSSVSGRVINSSHLQLSHNGNKKESGTHEHTHRPADVNGGKFSYTGHISRGDSVDNDVNGEKFSFSDHISGGDSGDEDANREKFIYSDHISEGENGPDVNSGTNWLQMHSEREVRLHMPVPAELEARFHISSERRTRLNVP-PARGSLSRHLAPNAPICPADWKADDWKHSNAGVVSLTADMPVVVSLTPTPPPLRDDSVSGIKQNERSSPGHREQYFLDKSQEPSSVVADQCSPGINGTPQSVCVIHQQSPSALGNGFQSSSQQAKVSSCASPKGTVSSGGAVSNRIANSSDMEEINTKDLAQRISAELKRYSIPQAIFAQRVLCRSQGTLSDLLRNPKPWSKLKSGRETFRRMYKWLQEPEFQRMSALRMAAAQIPQRAPLSSGMSLGSATGPSGSTGTIPTDLDPHGGPTMIQNPLTNESDSSPASTPVTSVLVGSVVSCRRKEEPQIEQMPQPKKPRLVFTDLQRRTLQAIFKETKRPSKEMQVT-----IARQLGLEPTTVGNFFMNARRR---SMDKWRDDDSKSTMHVAHSRQQQDEQQKDNAHTHSQSQIQDQNHSQNQAIHNSMSQDPYSNLHTTAMSPLGAFDEDADMDLELESHDFDLVDPDEHGDTNDPNGDML", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : :*. : .: : . *. : * : *: ::: :. :. : * * :: .: :*:****:* ***:: :::** ... : . * :. .:*:.:: . . *:.: :. * * . :. * . *:. * :* : : : . *: : : .. ::. . :*.:.:: : . * . . . . . : .. . * . ******::****:****************:*******************************:***************:*. :.: : : . * . .: :*: .: ..:.: : :** * : . : .* * : .: . . : ", "identical_positions": 110, "similar_positions": 127, "identity": "10.05%" }, { "cls_id": "homologset.agr.MGI:1891410", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I6AS02-1", "uniprot_id": "A0A8I6AS02_RAT", "id": "A0A8I6AS02-1", "name": "", "aln": "MPGVKSRGGEKLEKQGSLQRSLALPRVLGVLCSIGTPSRVWKAVSWRTSYENMCVSQAEVELRSKALHSRSRTLSLTSALTTAATIPCCRDTMAPEEDAGGEVLG-GSFWEAGNYRRTVQRVEDGHRLCGDLISCFQERARIEKAYAQQLADWARKWRGAVEKGPQYGTLEKAWHAFFTAAERLSELHLEVREKLHGPDSERVRTWQRGAFHRPVLGGFRESRAAEDGFRKAQKPWLKRLKEVEASKKSYHTARKDEKTAQTRESHAKADSSMSQEQLRKLQERVGRCTKEAEKMKTQYEQTLAELNRYTPRYMEDMEQAFESCQAAERQRLLFFKDVLLTLHQHLDLSSSDKFHELHRDLQRGIEDASDEEDLRWWRSTHGPGMAMNWPQFEEWSLDT----------------------QRAISR------KEKGGRSPDEVTLTSIVP--------------------------TRDGTAPPPQSPSSPGSGQDEDWS-----------DEESPRK-----------AGTGVRVRALYDYAGQEADELSFRAGEELLKMSEEDEQGWCQGQLQSGRIGLYPANYVECVGA", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q99JB8-1", "uniprot_id": "PACN3_MOUSE", "id": "Q99JB8-1", "name": "Protein kinase C and casein kinase II substrate protein 3", "aln": "--------------------------------------------------------------------------------------------MAPEEDAGGEVLG-GSFWEAGNYRRTVQRVEDGHRLCGDLVSCFQERARIEKAYAQQLADWARKWRGAVEKGPQYGTLEKAWHAFFTAAERLSELHLEVREKLHGPDSERVRTWQRGAFHRPVLGGFRESRAAEDGFRKAQKPWLKRLKEVEASKKSYHTARKDEKTAQTRESHAKADSSMSQEQLRKLQERVGRCTKEAEKMKTQYEQTLAELNRYTPRYMEDMEQAFESCQAAERQRLLFFKDVLLTLHQHLDLSSSDKFHELHRDLQQSIEAASDEEDLRWWRSTHGPGMAMNWPQFEEWSLDT----------------------QRAISR------KEKGGRSPDEVTLTSIVP--------------------------TRDGTAPPPQSPSSPGSGQDEDWS-----------DEESPRK-----------VATGVRVRALYDYAGQEADELSFRAGEELLKMSEEDEQGWCQGQLQSGRIGLYPANYVECVGA", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9UKS6-1", "uniprot_id": "PACN3_HUMAN", "id": "Q9UKS6-1", "name": "Protein kinase C and casein kinase substrate in neurons protein 3", "aln": "--------------------------------------------------------------------------------------------MAPEEDAGGEALG-GSFWEAGNYRRTVQRVEDGHRLCGDLVSCFQERARIEKAYAQQLADWARKWRGTVEKGPQYGTLEKAWHAFFTAAERLSALHLEVREKLQGQDSERVRAWQRGAFHRPVLGGFRESRAAEDGFRKAQKPWLKRLKEVEASKKSYHAARKDEKTAQTRESHAKADSAVSQEQLRKLQERVERCAKEAEKTKAQYEQTLAELHRYTPRYMEDMEQAFETCQAAERQRLLFFKDMLLTLHQHLDLSSSEKFHELHRDLHQGIEAASDEEDLRWWRSTHGPGMAMNWPQFEEWSLDT----------------------QRTISR------KEKGGRSPDEVTLTSIVP--------------------------TRDGTAPPPQSPGSPGTGQDEEWS-----------DEESPRK-----------AATGVRVRALYDYAGQEADELSFRAGEELLKMSEEDEQGWCQGQLQSGRIGLYPANYVECVGA", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M2BE23-1", "uniprot_id": "A0A8M2BE23_DANRE", "id": "A0A8M2BE23-1", "name": "", "aln": "--------------------------------------------------------------------------------------------MSSNGDLQDVGSW-DSFWEPGNYKRTVKRIDDGYKLCNELVSCFQERAKIEKGYSQQLSDWARKWRGIVEKGSQYGTLEKAWHAFMNAADRLSEIHMELKENLVIEDSEKIRNWQKDAFHKQMIGGFRETKDADEGFRKAQKPWVRKLKEVESTKKGYHSARKEERTALTRETHAKADPTKSQDEVRKFTDRLEKCTQEAEKAKERYERALDELNRCNPRYMEDMEQVFEITQEAEKNRLCFFKEVLLDIHQHMDLSSNDRFRALYRDLGQTISAANDTEDLRWWRNTHGPGMSMNWPQFEEWSPEA----------------------NRSISR------KDRNSRSDDVVTLTNIVS--------------------------AGDEPPQTLQETTRAGKDYSSDWS-----------DEESPKKYIAANGVDEEEKVVGVRVRALYDYTGQEADELSFKAGEELLKLGEEDEQGWCKGQLTSGEKGLYPANYVQIITS", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A0B4KH28-1", "uniprot_id": "A0A0B4KH28_DROME", "id": "A0A0B4KH28-1", "name": "", "aln": "--------------------------------------------------------------------------------------------MSHHSDDQLLQAGSDSFWEPGNYKRTTKRIEDGYKLCNDLQQLIQERADIEKGYAKSLRTWSKKWGELIEKGPEYGTTEAAWKGVLTESERISDVHMKIKDNLCNDVNSQIKTWQKENYHHTLMQ-IKERKDLEDLFKKAQKPWAKLLAKVEKAKADYHSACKTERSATNQERNANADSSLSPDQVKKMHDRVQKTKDQVQKCREKYEQAIAEITKYNSVYIEDMTSVFEKCQTFEKTRLQFFKEILFNVHSCLDLTKVQSLPQIYEEFSHTINNADQQKDLKWWSNNHGINMAMNWPSFVEYTEEFRDIAKGNKSKEALPAAPITLINQRPVAEDVHQEYPQTNSLKKNTSTLSSVSSRASVKSEIATTQSSVTTSEAKTSAAVAGAATATAAATAASAASNRNSSVTNGNGKVDANPFDEEEEWD--ESDNVLVDNGEPGVPVKALYDYEGAESDELTFKQGDVFEKLEDEDEQGWCKGRMN-GRVGLYPANYVETA--", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *: . * .****.***:**.:*::**::**.:* . :**** ***.*::.* *::** :***.:*** * **:..:. ::*:* :*::::::* ..::: **: :*: :: ::* : :: *:****** : * :** :* .**:* * *::* .:* :*:**.: * ::::*: :*: : .:.:* : :**::: *: : .. *:*** ..** * *: ** ***::*: :*. :**:. : : ::.:: : *. *.: :**:** ..** .*:****.* *:: : :*.::. : .. . : **:.: . : .. . . .... ... : ***. . ** *:***** * *:***:*: *: : *: :*******:*:: *. ********: ", "identical_positions": 145, "similar_positions": 164, "identity": "24.45%" }, { "cls_id": "homologset.agr.MGI:1891413", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZMN0-1", "uniprot_id": "D3ZMN0_RAT", "id": "D3ZMN0-1", "name": "", "aln": "MGPKKNSKLQESGGSK----TSIKFEKQLGPDDEEMYDTTAQSKFVLKNLRHYTVHPNMAQYYEPLKPSKLQRFLTQRKKTNSFMVKVTEYDQDMTLLLMTNNPPPYSIGQQENNGAPIYFPPEFQLK--ETVYRREPNKNDFLPTMSQKKKLKPVLKPIFPMKRIGDPNFKGQQWFRFSTDKDFKIEGRYSEVHALRKQKKMYPNLIFAPVDQRETRKQVSMKSADETPTSQVLWEPLTFSKLLEEKPTRSVPGESCFRYGRAQQWVVKNAAVIK", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9DA17-1", "uniprot_id": "TSG13_MOUSE", "id": "Q9DA17-1", "name": "Testis-specific gene 13 protein", "aln": "MGPKKNSKFQEVSGSKPVGNVSIRFEKQLGQDDEEMYDTTAQSKFVLKNLRHYTVHPNMAKYYEPLKPTKLQRFLTQKKKMNSFMLKVTEYDQDMTLLLMTNNPPPCSISQ-EKDGAPIYFPPEFQLK--ETLHRCKPNKNDFFPTMSQKKKLKPELKPVFPMKRLDDPTFKGQQWFRFSTDNDFNIEGKYSEIYALRKQKKMYPNLIFAPASQRETKKHVSMKSESETPTSQVFWEPLTFSKLLEEKPTRSVPGESFFRHGRAQQWIVKDAAVIW", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q96PP4-1", "uniprot_id": "TSG13_HUMAN", "id": "Q96PP4-1", "name": "Testis-specific gene 13 protein", "aln": "MSQKRQTKFQN-GKSKTSENSSAKREKGMVVNSKEISDAVGQSKFVLENLRHYTVHPNLAQYYKPLKATALQKFLAQNRKNTSFMLKVTQYDQDKTLLIMTNNPPPCSITQQDKESASKYFSKELLLKVMESHHQHKPTENLWLPRMPQKKKLRSKLKPIFPLILSDDPTSKREQWFRFSTDNDFKSEGKYSKVYALRTQKKMYPQLTFAPVHERDMRKDASKKSASERPISKVIREPLTLASLLEDMPTRTAPGESAFRNGRAPQWIIKKATVIG", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*. *:::*:*: . ** * : ** : :.:*: *:..******:**********:*:**:***.: **:**:*.:* .***:***:**** ***:******* ** * :::.*. **. *: ** *: :: :*.:* ::* *.*****:. ***:**: .**. * :********:**: **:**:::***.******:* ***. :*: :*..* ** .* * *:*: ****::.***: ***:.**** ** *** **::*.*:** ", "identical_positions": 147, "similar_positions": 80, "identity": "53.26%" }, { "cls_id": "homologset.agr.MGI:1891414", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q4KM37-1", "uniprot_id": "CEP41_RAT", "id": "Q4KM37-1", "name": "Centrosomal protein of 41 kDa", "aln": "MSDSPIDGSP----------------------------------QPEPDYRYKKDELFKRIKVTTFAQLVIQVASLSDQTLEVTAEEIQRLEDSDSATSEADTDIAAKTNGKGSPEEQSPSPVQFINSTGAGD---ASRSTLQSVISGVGELDVDKG------LVKKEEPSGKDKPYPDCPFLLLDVRDRDSYQQCHIVGAYSYPIATLSRTMNPYSNDILEYKNAHGKIIILYDDDERLASQAATTMCERGFENLFMLSGGLKVLAQKFPEGLVTGSLPASCQQALPFGSVRKRPGPKMPALPAENKWRFTPEDLKKIECYLEADQGPANNPSRLNQNNSAGRDLKVPAGRGGQNLPTGCPTSHSNSRTLNSGHLQGKPWK", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q99NF3-1", "uniprot_id": "CEP41_MOUSE", "id": "Q99NF3-1", "name": "Centrosomal protein of 41 kDa", "aln": "MSARRHIGNPEYLTRRIPQNPRYQHVKSRLDTGNSMTKYIEKLEEIKKNYRYKKDELFKRLKVTTFAQLVIQVASLSDQTLEVTAEEIQRLEDNDSATSEADAEIAAKTNGKGSPEEQSPSPVQFINSTGAGD---SSRSTLQSVISGVGELDVDKG------LVKKEEPNGKDKPYPDCPFLLLDVRDRDSYQQCHIVGAYSYPIATLSRTMNPYSNDILEYKNAHGKIIILYDEDERLASQAATTMCERGFENLFMLSGGLKVLAQKFPEGLVTGSLPASCQQALPFGSVRKRRGPKMPALPAENKWRFTPEDLKKIECYLEEDQGPADNPSRLNQNNSAGKDSKVAACRGGQNLPTSCPASHSSPRTLTSGHLQGKPWK", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9BYV8-1", "uniprot_id": "CEP41_HUMAN", "id": "Q9BYV8-1", "name": "Centrosomal protein of 41 kDa", "aln": "MSLRRHIGNPEYLMKRIPQNPRYQHIKSRLDTGNSMTKYTEKLEEIKKNYRYKKDELFKRLKVTTFAQLIIQVASLSDQTLEVTAEEIQRLEDNDSAASDPDAETTARTNGKGNPGEQSPSPEQFINNAGAGD---SSRSTLQSVISGVGELDLDKG------PVKKAEPHTKDKPYPDCPFLLLDVRDRDSYQQCHIVGAYSYPIATLSRTMNPYSNDILEYKNAHGKIIILYDDDERLASQAATTMCERGFENLFMLSGGLKVLAQKFPEGLITGSLPASCQQALPPGSARKRSSPKGPPLPAENKWRFTPEDLKKIEYYLEEEQGPADHPSRLNQANSSGRESKVPGARSAQNLPGGGPASHSNPRSLSSGHLQGKPWK", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6GQN0-1", "uniprot_id": "CEP41_DANRE", "id": "Q6GQN0-1", "name": "Centrosomal protein of 41 kDa", "aln": "MSVKRGIGDSAFLKKKIPQNPKYQHVKTRLDTGSSLTKYMERLEEARKNYRYRKDELFKRLKVTTFAQLVIQVASVSDQN-DNIKDEMAGLEDDVSIFSASPGLDCLSDQTNGSPQPNLPPP-QTINIDESGDNGFSPRSTLQSVISGVGELDLDKNGQKTIRLSPVSTSNTTECPYPDCPYLLLDVRDRELYDQCHIVSAYSYPIATLSRTMNPYTKEVLDYKNASGKIIIVYDEDERIASQAATTMCERGFENLFMLSGGLKVVAQKFPEGMTTGSVPISCLPSPTGPAGRKRSAQHQTSQLAEKKWRFTAEDLDKIQHYLEEVFIPSETSSRLSSRMSTS-SARSKASTVGSSRQGSSIAGSESARSRSS-----RPWK", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "** *.. : . :***:*******:********:*****:***. : :*: ***. * * . : :*.* : *.* * ** :** :.***************:**. . .: ******:********: *:*****.****************::::*:**** *****:**:***:*************************:*******: ***:* ** : . : *** . : .. **:*****.***.**: *** *:: .***.. *:. . : . ... . :. ...*: .* :***", "identical_positions": 178, "similar_positions": 76, "identity": "46.6%" }, { "cls_id": "homologset.agr.MGI:1891420", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9ERE8-1", "uniprot_id": "TLRN1_MOUSE", "id": "Q9ERE8-1", "name": "Talin rod domain-containing protein 1", "aln": "MASGSAGKPTGEAASPAPGSAVGGASSQPRKRLVSICDHCKGKMQLVADLLLLSSEARPVLFEGPASPGAGAESFEQCRDTIIARTKGLSILTHDVQSQLNMGRFGEAGDSLVELGDLVVSLTECSAHAAYLAAVATPGAQPAQPGLVDRYRVTRCRHEVEQGCAVLRATPLADMTPQLLLEVSQGLSRNLKFLTDACALASDKSRDRFSREQFKLGVKCMSTSASALLACVREVKAAPSELARSRCALFSGPLVQAVSALVGFATEPQFLGRAAAVSTEGKAVQTAILGGAMSVVSACVLLTQCLRDLAQHPDGSAKMSDHRERLRNSACAVSEGCTLLSQALRERSSPRTLPPVNSNSVN", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q5BJV3-1", "uniprot_id": "Q5BJV3_RAT", "id": "Q5BJV3-1", "name": "Talin rod domain-containing protein 1", "aln": "MASGSAGKPTGEAASPAPGSAVGGASSQPRKRLVSICDHCKGKMQLVADLLLLSSEARPVLFEGPASPGAGAESFEQCRDTIIARTKGLSILTHDVQSQLNMGRFGEAGDSLVELGDLVVSLTECSAHAAYLAAVATPGAQPAQPGLVDRYRVTRCRHEVEQGCAVLRATPLADMTPQLLLEVSQGLSRNLKFLTDACALASDKSRDRFSREQFKLGVKCMSTSASALLACVREVKAAPSELARSRCALFSGPLVQAVSALVGFATEPQFLGRAAAVSTEGKAVQTAILGGAMSVVSACVLLTQCLRDLAQHPDGSAKMSDHRERLRNSACAVSEGCTLLSQALRERSSPRTLPPVNSNSVN", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9H1K6-1", "uniprot_id": "TLRN1_HUMAN", "id": "Q9H1K6-1", "name": "Talin rod domain-containing protein 1", "aln": "MASGSAGKPTGEAASPAPASAIGGASSQPRKRLVSVCDHCKGKMQLVADLLLLSSEARPVLFEGPASSGAGAESFEQCRDTIIARTKGLSILTHDVQSQLNMGRFGEAGDSLVELGDLVVSLTECSAHAAYLAAVATPGAQPAQPGLVDRYRVTRCRHEVEQGCAVLRATPLADMTPQLLLEVSQGLSRNLKFLTDACALASDKSRDRFSREQFKLGVKCMSTSASALLACVREVKVAPSELARSRCALFSGPLVQAVSALVGFATEPQFLGRAAAVSAEGKAVQTAILGGAMSVVSACVLLTQCLRDLAQHPDGGAKMSDHRERLRNSACAVSEGCTLLSQALRERSSPRTLPPVNSNSVN", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AA53EER7-1", "uniprot_id": "A0AA53EER7_DANRE", "id": "A0AA53EER7-1", "name": "", "aln": "MASSGSGKSD----SEVPTNILSGSLQQ-RKRLLSVCDACKSKMQLVADLLLLSSETRPVVNT---EGQPVAETFEKCRDTVIARTKELSIIVHDIQSQLNMGKFLEVGDRLVEMGDLVVSLTEYSAHAAYLAAAEIPGSQAAVSGLVDRYKVTRCRHEVEQTCNILRLTAVGDLTPPLLLEVSQNILKNLTMLTDASSLASDKSKDKFAKEQFKASVKCMSTSATALLACVRELKACPSELTRNRCVLFSGPLIQAVHALVGFATEPQFLGKAASITPDGKGVQTAVLGGAMSVVSACVLLTQGLRDISQHPESSQQMPVYRERLRNSACAVSDGCTLLSQALRERSSPRTLPPVNSHSVN", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "***..:**. * .* . :.*: .* ****:*:** **.**************:***: . . **:**:****:***** ***:.**:*******:* *.** ***:********* *********. **:*.* .******:********** * :** *.:.*:** *******.: :**.:****.:******:*:*::**** .********:********:*..****:*.**.******:*** *************:**:::.:**.****:**************** ***::***:.. :*. :************:***********************:***", "identical_positions": 252, "similar_positions": 74, "identity": "69.61%" }, { "cls_id": "homologset.agr.MGI:1891421", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q5U2R7-1", "uniprot_id": "MESD_RAT", "id": "Q5U2R7-1", "name": "LRP chaperone MESD", "aln": "MAASSWLRAVLLFLCASD----LLLLSPPEAYATD----TPGEAITPPRKKK-DIRDYNDADMARLLEQWEKDDD-IEEGDLPEHKRPSAPIDFSKLDPGKPESILKMTKKGKTLMMFVTISGNPTEKETEEITSLWQGSLFNANYDVQRFIVGSDRAIFMLRDGSYAWEIKDFLVNQDRCAEVTLEGQMYPGKGGGSKEKNKTKPEKGKKK-EGDPKPRASKEDNRAGSRREDL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9ERE7-1", "uniprot_id": "MESD_MOUSE", "id": "Q9ERE7-1", "name": "LRP chaperone MESD", "aln": "MAASRWLRAVLLFLCASD----LLLLPPPNAYAAD----TPGEATPPPRKKK-DIRDYNDADMARLLEQWEKDDD-IEEGDLPEHKRPSAPIDFSKLDPGKPESILKMTKKGKTLMMFVTVSGNPTEKETEEITSLWQGSLFNANYDVQRFIVGSDRAIFMLRDGSYAWEIKDFLVSQDRCAEVTLEGQMYPGKGGGSKEKNKTKPEKAKKK-EGDPKPRASKEDNRAGSRREDL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q14696-1", "uniprot_id": "MESD_HUMAN", "id": "Q14696-1", "name": "LRP chaperone MESD", "aln": "MAASRWARKAVVLLCASDLLLLLLLLPPPGSCAAEGSPGTPDESTPPPRKKKKDIRDYNDADMARLLEQWEKDDD-IEEGDLPEHKRPSAPVDFSKIDPSKPESILKMTKKGKTLMMFVTVSGSPTEKETEEITSLWQGSLFNANYDVQRFIVGSDRAIFMLRDGSYAWEIKDFLVGQDRCADVTLEGQVYPGKGGGSKEKNKTKQDKGKKKKEGDLKSRSSKEENRAGNKREDL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A1L243-1", "uniprot_id": "MESD_DANRE", "id": "A1L243-1", "name": "LRP chaperone MESD", "aln": "MASSVGCRTLSVLF---------LLVLFITVHCTD----------TKPKKKK-DIRDYNDADMARLLEEWEKDDD-IEEGDLPEHKRSPPPIDFSKIDASKPEELLKMSKKGKTLMVFASVSGNPTEKETEEITGLWQGSLFNANYDVQRFVVGSNRVIFMLRDGSYAWEIKDFLVSQDRCEDVTVEGQVFPGKN--AKKDAKGKEQNETKK-KGDKK-----AANRANKGKQEL", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q8T9B6-1", "uniprot_id": "MESD_DROME", "id": "Q8T9B6-1", "name": "LDLR chaperone boca", "aln": "MQT----RLVLLLLALTP------LVLAKKFKEEE----------KPAWAKK-DIRDYSEADLERLLDQWEEDEEPLEDDELPEHLRPQPKLDLSNLDSKSPEDLLKVSKKGRTLMTFVSVTGNPTREESDTITKLWQTSLWNNHIQAERYMVDDNRAIFLFKDGTQAWDAKDFLIEQERCKGVTIENKEYPGVN----------------------------------AKKDEL", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* : * ::: *: : . ** *****.:**: ***::**:*:: :*:.:**** *. . :*:*::*. .**.:**::***:*** *.:::*.**.:*:: ** *** **:* : :.:*::*..:*.**:::**: **: ****: *:** **:*.: :** . :::*", "identical_positions": 72, "similar_positions": 67, "identity": "30.64%" }, { "cls_id": "homologset.agr.MGI:1891427", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8VI82-1", "uniprot_id": "FGF23_RAT", "id": "Q8VI82-1", "name": "Fibroblast growth factor 23", "aln": "MLGACLRLLVGALCTVCSLGTARAYSDTSPLLGSNWGSLTHLYTATARNSYHLQIHRDGHVDGTPHQTIYSALMITSEDAGSVVIIGAMTRRFLCMDLRGNIFGSYHFSPENCRFRQWTLENGYDVYLSPKHHYLVSLGRSKRIFQPGTNPPPFSQFLARRNEVPLLHFYTARPRRHTRSAEDPPERDPLNVLKPRPRATPIPVSCSRELPSAEEGGPAASDPLGVLRRGRGDARRGAGGTDRCRPFPRFV", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9EPC2-1", "uniprot_id": "FGF23_MOUSE", "id": "Q9EPC2-1", "name": "Fibroblast growth factor 23", "aln": "MLGTCLRLLVGVLCTVCSLGTARAYPDTSPLLGSNWGSLTHLYTATARTSYHLQIHRDGHVDGTPHQTIYSALMITSEDAGSVVITGAMTRRFLCMDLHGNIFGSLHFSPENCKFRQWTLENGYDVYLSQKHHYLVSLGRAKRIFQPGTNPPPFSQFLARRNEVPLLHFYTVRPRRHTRSAEDPPERDPLNVLKPRPRATPVPVSCSRELPSAEEGGPAASDPLGVLRRGRGDARGGAGGADRCRPFPRFV", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9GZV9-1", "uniprot_id": "FGF23_HUMAN", "id": "Q9GZV9-1", "name": "Fibroblast growth factor 23", "aln": "MLGARLRLWVCALCSVCSMSVLRAYPNASPLLGSSWGGLIHLYTATARNSYHLQIHKNGHVDGAPHQTIYSALMIRSEDAGFVVITGVMSRRYLCMDFRGNIFGSHYFDPENCRFQHQTLENGYDVYHSPQYHFLVSLGRAKRAFLPGMNPPPYSQFLSRRNEIPLIHFNTPIPRRHTRSAEDDSERDPLNVLKPRARMTPAPASCSQELPSAEDNSPMASDPLGVVRGGRVNTHAGGTGPEGCRPFAKFI", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "***: *** * .**:***:.. ***.::******.**.* ********.*******::*****:*********** ***** *** *.*:**:****::****** :*.****:*:: ********* * ::*:******:** * ** ****:****:****:**:** * ********** .***********.* ** *.***:******:..* *******:* ** ::: *. *.: ****.:*:", "identical_positions": 174, "similar_positions": 50, "identity": "69.32%" }, { "cls_id": "homologset.agr.MGI:1891428", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I6B3E0-1", "uniprot_id": "A0A8I6B3E0_RAT", "id": "A0A8I6B3E0-1", "name": "Protocadherin-15", "aln": "MSPQFALWKCMPHGILLASLLIVSWGQYDD-----DCKLARGGPPATIVAIDEESRNGTILVDNMLIKGTAGGPDPTIELSLKDNVDYWVLLDPVKQMLFLNSTGRVLDRDPPMNIHSIVVQVQCVNKKVGTVIYHEVRIVVRDRNDNSPTFKHESYYATVNELTPVGTTIFTGFAGDNGATDIDDGPNGQIEYVIQYNPEDPT--------SNDTFEIPLMLTGNVVLRKRLNYEDKTRYYVIIQANDRAQNLNERRTTTTTLTVDVLDGDDLGPMFLPCVLVPNTRDCRPLTYQAAIPELRTPEELNPILVTPPIQAIDQDRNIQPPSDRPGILYSILVGTPEDYPRFLHMHPRTAELTLLEPVNRDFHQKFDLVIKAEQDN-GHPLPAFASLHIEILDENNQSPYFTMPSYQGYILESAPVGATISESLNLTTPLRIVALDKDIEDTKDPELHLFLNDYTSVFTVTPTGITRYLTLLQPVDREEQQTYTFLITAFDGVQ--ESEPVVVNIRVMDANDNTPTFPEISYNVYVYTDMSPGDSVIQLTAVDADEGSNGEISYEILVGSKG---DFVINRTTGLVSIAPGVELVVGQTYALTVQASDNAPPAERRHSICTVYIEVLPPNNQSPPRFPQLMYSLEVSEAMRIGAVLLNLQATDREGDPITYAIENGDPQRVFNLSETTGILSLGKALDRESTDRYILIVTASDGRPDGTSTATVNIVVTDVNDNAPVFDP-YLPRNLSVVEEEANAFVGQVRATDPDAGINGQVHYSLGNFNNLFRITSNGSIYTAVKLNREARDHYELVVVATDGAVHPRHSTLTLYIKVLDIDDNSPVFTNSTYTVVVEENLPAGTAFLQIEAKDVDLGANVSYRIRSPEVKHLFALHPFTGELSLLRSLDYEAFPDQEASITFLVEAFDIYGTMPPGIATVTVIVKDMNDYPPVFSKRIYKGMVAPDAVKGTPITTVYAEDADPPGLPASRVRYRVDDVQFPYPASIFDVEEDSGRVITRVNLNEEPTTIFKLVVVAFDDGEPVMSSSATVRILVLHPGEIPRFTQEEYRPPPVSELAARGTVVGVISAAAINQSIVYSIVAGNEDDKFGINNVTGVIYVNSPLDYETRTSYVLRVQADSLEVVLANLRVPSKSNTAKVYIEIQDENDHPPVFQKKFYIGGVSEDARMFTSVLRVKATDRDTGNYSAMAYRLIIPPIKEGKEGFVVETYTGLIKTAMLFHNMRRSYFKFQVIATDDYGKGLSGKADVLVSVVNQLDMQVIVSNVPPTLVEKKIEDLTEILDRYVQEQIPGAKVVVESIGARRHGDAFSLEDYSKCDLTVYAIDPQTNRAIDRNELFKFLDGKLLDINKDFQPYYGEGGRILEIRTPEAVTSIKKRGESLGYTEGALLALAFIIILCCIPAILVVLVSYRQFKVRQAECTKTARIQSAMPAAKPAAPVPAAP--PPPPPPPPPGAHLYEELGESAI--LFLLYHFEQSRGNNPVPEDRSSHRDGMAFSSSTTESHEPAHVEGPLDN-QANPARTFSFLPDEDDLSTHNPLYMESIGQRSTNSDLQPGTEFGELFVPRTQVKSQSLRGPREKIQRVWNQSVRFPRRLMWKTPNRPETIDLVEWQITRQRAECEKTRCHPSQQGSSNLMVTTEDARGSEKEGGHR-DTLIVQQTEQLKSLSSGSSFSSSWSHFSFSTLPTISRAVELGSEPDVVTSPADCTLELSPPRRPRVLNSLGSKRETPTCASDTETKRNSFEMVPHP---PSIS---APLPQLPLPQPP---------------IAFTTFPLPLSSPNP----PRPQLLTFSLPISTTPASSLPPPPPPSLPPPPRPPAPRLFPLPPSTSVPSTDSISTPAAKCTASVTHARETMSTTQPPASNPPCGAEPHRHPKGILRHVKNLAELEKSVSNMYSHIEKNCPPTELSKLHPFCPAEKTNMKITCDQSQETLVRVVEGIDVQTHSQSTSL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q99PJ1-1", "uniprot_id": "PCD15_MOUSE", "id": "Q99PJ1-1", "name": "Protocadherin-15", "aln": "MFLQFAVWKCLPHGILIASLLVVSWGQYDDDWQYEDCKLARGGPPATIVAIDEESRNGTILVDNMLIKGTAGGPDPTIELSLKDNVDYWVLLDPVKQMLFLNSTGRVLDRDPPMNIHSIVVQVQCVNKKVGTVIYHEVRIVVRDRNDNSPTFKHESYYATVNELTPVGTTIFTGFSGDNGATDIDDGPNGQIEYVIQYNPEDPT--------SNDTFEIPLMLTGNVVLRKRLNYEDKTRYYVIIQANDRAQNLNERRTTTTTLTVDVLDGDDLGPMFLPCVLVPNTRDCRPLTYQAAIPELRTPEELNPILVTPPIQAIDQDRNIQPPSDRPGILYSILVGTPEDYPRFFHMHPRTAELTLLEPVNRDFHQKFDLVIKAEQDN-GHPLPAFASLHIEILDENNQSPYFTMPSYQGYILESAPVGATISESLNLTTPLRIVALDKDIEDTKDPELHLFLNDYTSVFTVTPTGITRYLTLLQPVDREEQQTYTFLITAFDGVQ--ESEPVVVNIRVMDANDNTPTFPEISYDVYVYTDMSPGDSVIQLTAVDADEGSNGEISYEILVGGKG---DFVINKTTGLVSIAPGVELIVGQTYALTVQASDNAPPAERRHSICTVYIEVLPPNNQSPPRFPQLMYSLEVSEAMRIGAILLNLQATDREGDPITYAIENGDPQRVFNLSETTGILSLGKALDRESTDRYILIVTASDGRPDGTSTATVNIVVTDVNDNAPVFDP-YLPRNLSVVEEEANAFVGQVRATDPDAGINGQVHYSLGNFNNLFRITSNGSIYTAVKLNREARDHYELVVVATDGAVHPRHSTLTLYIKVLDIDDNSPVFTNSTYTVVVEENLPAGTSFLQIEAKDVDLGANVSYRIRSPEVKHLFALHPFTGELSLLRSLDYEAFPDQEASITFLVEAFDIYGTMPPGIATVTVIVKDMNDYPPVFSKRIYKGMVAPDAVKGTPITTVYAEDADPPGMPASRVRYRVDDVQFPYPASIFDVEEDSGRVVTRVNLNEEPTTIFKLVVVAFDDGEPVMSSSATVRILVLHPGEIPRFTQEEYRPPPVSELAARGTVVGVISAAAINQSIVYSIVAGNEEDKFGINNVTGVIYVNSPLDYETRTSYVLRVQADSLEVVLANLRVPSKSNTAKVYIEIQDENDHPPVFQKKFYIGGVSEDARMFASVLRVKATDRDTGNYSAMAYRLIIPPIKEGKEGFVVETYTGLIKTAMLFHNMRRSYFKFQVIATDDYGKGLSGKADVLVSVVNQLDMQVIVSNVPPTLVEKKIEDLTEILDRYVQEQIPGAKVVVESIGARRHGDAYSLEDYSKCDLTVYAIDPQTNRAIDRNELFKFLDGKLLDINKDFQPYYGEGGRILEIRTPEAVTSIKKRGESLGYTEGALLALAFIIILCCIPAILVVLVSYRQFKVRQAECTKTARIQSAMPAAKPAAPVPAAPAPPPPPPPPPPGAHLYEELGESAMHNLFLLYHFEQSRGNNSVPEDRSSHRDGMAFSSSTTESHEPAHVEGPLKESQPNPARTFSFVPDEDNLSTHNPLYMESIGQRSTNSDLQPRTDFEELLAPRTQVKSQSLRGPREKIQRVWNQSVSFPRRLMWKAPNRPETIDLVEWQITNQRAECESARCHPSQRGSSNVLLATEDAHESEKEGGHR-DTLIVQQTEQLKSLSSGSSFSSSWSHFSFSTLPTISRAVELGSEPNVVTSPADCTLELSPPLRPRILNSLSSKRETPTCASDTEPKRNSFEIAPHP---PSIS---APLPHPPLPRPP---------------IAFTTFPLPLSPPNP----PPPQLVTFSLPISTPPTSSLPLPPPLSLPPPPRPPAPRLFPQPPSTSIPSTDSISAPAAKCTASATHARETTSTTQPPASNPQWGAEPHRHPKGILRHVKNLAELEKSVSNMYSHIEKNCPPADPSKLHTFCPAEKTGMKITHDQSQETLVRVVEGIDVQPHSQSTSL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q96QU1-1", "uniprot_id": "PCD15_HUMAN", "id": "Q96QU1-1", "name": "Protocadherin-15", "aln": "MFRQFYLWTCLASGIILGSLFEICLGQYDD-----DCKLARGGPPATIVAIDEESRNGTILVDNMLIKGTAGGPDPTIELSLKDNVDYWVLMDPVKQMLFLNSTGRVLDRDPPMNIHSIVVQVQCINKKVGTIIYHEVRIVVRDRNDNSPTFKHESYYATVNELTPVGTTIFTGFSGDNGATDIDDGPNGQIEYVIQYNPDDPT--------SNDTFEIPLMLTGNIVLRKRLNYEDKTRYFVIIQANDRAQNLNERRTTTTTLTVDVLDGDDLGPMFLPCVLVPNTRDCRPLTYQAAIPELRTPEELNPIIVTPPIQAIDQDRNIQPPSDRPGILYSILVGTPEDYPRFFHMHPRTAELSLLEPVNRDFHQKFDLVIKAEQDN-GHPLPAFAGLHIEILDENNQSPYFTMPSYQGYILESAPVGATISDSLNLTSPLRIVALDKDIEDTKDPELHLFLNDYTSVFTVTQTGITRYLTLLQPVDREEQQTYTFSITAFDGVQ--ESEPVIVNIQVMDANDNTPTFPEISYDVYVYTDMRPGDSVIQLTAVDADEGSNGEITYEILVGAQG---DFIINKTTGLITIAPGVEMIVGRTYALTVQAADNAPPAERRNSICTVYIEVLPPNNQSPPRFPQLMYSLEISEAMRVGAVLLNLQATDREGDSITYAIENGDPQRVFNLSETTGILTLGKALDRESTDRYILIITASDGRPDGTSTATVNIVVTDVNDNAPVFDP-YLPRNLSVVEEEANAFVGQVKATDPDAGINGQVHYSLGNFNNLFRITSNGSIYTAVKLNREVRDYYELVVVATDGAVHPRHSTLTLAIKVLDIDDNSPVFTNSTYTVLVEENLPAGTTILQIEAKDVDLGANVSYRIRSPEVKHFFALHPFTGELSLLRSLDYEAFPDQEASITFLVEAFDIYGTMPPGIATVTVIVKDMNDYPPVFSKRIYKGMVAPDAVKGTPITTVYAEDADPPGLPASRVRYRVDDVQFPYPASIFEVEEDSGRVITRVNLNEEPTTIFKLVVVAFDDGEPVMSSSATVKILVLHPGEIPRFTQEEYRPPPVSELATKGTMVGVISAAAINQSIVYSIVSGNEEDTFGINNITGVIYVNGPLDYETRTSYVLRVQADSLEVVLANLRVPSKSNTAKVYIEIQDENNHPPVFQKKFYIGGVSEDARMFTSVLRVKATDKDTGNYSVMAYRLIIPPIKEGKEGFVVETYTGLIKTAMLFHNMRRSYFKFQVIATDDYGKGLSGKADVLVSVVNQLDMQVIVSNVPPTLVEKKIEDLTEILDRYVQEQIPGAKVVVESIGARRHGDAFSLEDYTKCDLTVYAIDPQTNRAIDRNELFKFLDGKLLDINKDFQPYYGEGGRILEIRTPEAVTSIKKRGESLGYTEGALLALAFIIILCCIPAILVVLVSYRQFKVRQAECTKTARIQAALPAAKPAVPAPAPVAAPPPPPPPPPGAHLYEELGDSSI--LFLLYHFQQSRGNNSVSEDRKHQQVVMPFSSNTIEAHKSAHVDGSLKSNKLKSARKFTFLSDEDDLSAHNPLYKENISQVSTNSDISQRTDFVDPFSPKIQAKSKSLRGPREKIQRLWSQSVSLPRRLMRKVPNRPEIIDLQQWQGTRQKAENENTGICTNKRGSSNPLLTTEEANLTEKEEIRQGETLMIEGTEQLKSLSSDSSFCFPRPHFSFSTLPTVSRTVELKSEPNVISSPAECSLELSPS-RPCVLHSSLSRRETPICMLPIETERNIFENFAHP---PNISPSACPLPPPPPISPPSPPPAPAPLAPPPDISPFSLFCPPPSPPSIPLPLPPPTFFPLSVSTSGPPTPPLLPPFPTPLPPPP-PSIP--CPPPPSASFLSTECVCITGVKCTTNLMPAEKIKSSMTQLSTTTVCKTDPQREPKGILRHVKNLAELEKSVANMYSQIEKNYLRTNVSELQTMCPSEVTNMEITSEQNKGSLNNIVEGTEKQSHSQSTSL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VAF5-1", "uniprot_id": "CAD99_DROME", "id": "Q9VAF5-1", "name": "Cadherin-99C", "aln": "MAARNSLTPQQGLGFFGLLILLCSAVLGKS-----QMCEVETGQTNIILDIEESRESFIGQPTTPPELPIFGDPDTEIALNLVFPKGQPIFQLNGKKLQLLQPLDRDEE-----NLSHIVFQVSCTTRSTGKKRTIPIIVRVSDINDNAPRFMNTPYEVTVPESTPVGTTIFR----NIQALDKDAGVNGLVEYFIAEGSPNSTNVEKYSADGYGTFAISFPHQGQVTVAKTLDFEKIQTYYLTIVASDRARNTADRLSSTTTLTVNIADSNDLDPSFIYSGCVSLDGACINPEYSASVPAGSLLGVLT--VLPERIQAVDLDTINSP------IRYSFASGMPGNYADYFQIDESTGVLKQTKAVDTSTAKKYDIIVKAEEVSPGPQRFTTAKLEIFVKPVDANPPVISSSQAEGYVDENSPIGTRVLDAH--GNPISFMTTDADLSDS-DPKPDYIYELTTPSFNVTGDGILVVNEENLDRDPPAPGRFKFQVVAREPRTNAASAPLSLTVHLRDVNDNAPKLAMVAPISITAGDQSESRLVTQVTATDNDEGPNAVVTYSIYHVSNNGIQKFTINATTGEIRTQG--RLLAGEQYSITVQATDIG----GLSSQAIVEVSVTPGPNTKPPRFQKPIYEVQVSEGAEINSTVTVVHAEDPENDAVVYSIISGNDLRQFAVGQESGVIIVIRKLDRESLTRYQLILKAEDTG-GLSSSATVNIKVTDINDKNPEFEASTLPYVFQVEEGKAQASVGVVHATDADEGINAEITYSIPTDIPFTINATSGEILTAKELDYEQLNEYKFVVTAKDGAPDARLGTASVTVMVLDLPDEVPKFSDARIDVHIPENEEN-FLVATVQAFDPDSMPEITYVLRK-GNAELFKVSEKSGEVRTIKGLDYESQKQHQLTIG----TIENDGNGPGDTILLVVDVEDRNDLPPRFITVPDPVTVNDDQGIGTIIATLPAIDGDG-TSPGNVVRYEIVGRGK--APKYFQVDPDTGAVRIRDELRKEEDTEYQVDIRAYDLGEPQLSSVAPLRVDVHH-----------------------------------------LLSSGNNEIKLDNKLESGTGMSSESIG--------LAFSDDSYTTSVPESMEANSTLKLIQIVNSKTSGDGPPAFRCEFVSGNG-------GGIFNLSSADHGCN-------LLLIQPLD--------------------FENKSSYSLQLRLTSHRYFVNPLKDTTSVEIIVQDENDN-------APEFEFNRLRGQQDTFYTVVTEEMDVDTTILQVRATDRDSGKFGTVRYTLYDDDENRVNMPTSFFMMSEDTGVLRTAKHFKNENDFP-----------------LTFLVEARDSDGQEQGSHRTRARIVVN---------------------KLADINRMALSFPNAAPSDLR-----------------NYYTELEELLD-----------KKTGLVSGIERMSSQKYLAKNGSVIENPAATDIWFYLID-----PKTEQLVSRKD--SIVETTLLEPAARSELNIALPRATAENISFPLERKEHVHKVKAAVAIDNEVFPFTLIAISLVILILGTIGIIYICISWSKYKNFKQRMRQYSSTNPPRYDPVIVNQQASSASETIANMKEYETQMLAMAVPPDVDDDLQLDFSAKNHAFSLDNVSYITHKENTNGGGQSSPSHSDATTATIATLRRHKNLNN--ASMNNNLAINNRQNTFNRTLEMNTRN---------NANPLASPP----------------------------------NGALSGTLTLGRIKHQNSNHYQNGAYNIDPTG----------PNNMAHAKNNAYSTMGRRGNTFGDVGLLNGNGELMNATLGRNGQLNNRLYGGEVPITNPLFQRSNSDHNHLSSTNENVSFG----------------KRDYGQIGFSYLNDLDRSEVETTTEL---", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* : : *:: :: . .. : .. * . *: *:*. .. . *.**. * *.* . :: *:: :*:. .* : *: **.**.* .:..*. : : * * ***:* * : .* .** * ******** : * * * * ** :**.* .. :.* . .** *.: *::.: * *::*. *:: * *.***:* :* ::******:: *.:**.* *: . *. * *.*::* *. ::. ***:* * .* * **: * * :*. ::::. *. *. :.*: . :*:*:::***: . * : * *.* : : :.* :: .. :**: *.:*:*: : :: .*: ::: * *:.*: **: . : : *. *.** ** * :.* :.* : * *: :.::: *.***:*.:. :: . * . * *:**.* ***.*. ::*.* .:. .* ** *** : .::.*. *::****:* . * . * :.* * * .**** : :*.:::**. .:.: : ::* * *.*.:.*:* .*: * * :.: :*:: : : ***** ** **:.*.* . :*:***** ***:**: * *:. ** :.* * :*:* ** *:***.* ***.:: **: . : ::.*.* ** :*: * : *::**.*.*** ..* .* :: : ***: *: * *::: * : ** . ::* * * .:::* :*. .:* : :**: ::.****: ::: :* ::: *. * . :.* *:* ** ** * . * * ** *:*: * *.* *.. ***.: . ... *:*: *:* * * :*.:* * ::: : *:* *** :** *.::: * * : :**:: .:. : :*. . .:. * .. ** . :.: ...: . :: : ..: **.*: :* *. .::.:.::*:. . *:* *:. *.* ::::: : : : *...:.* : * :: * .* : :::.. : : * *:: ..::: .: *... :. *: * :: *. : :: : .* :. ::** :* : : :* * :*: : * *:: : :. *: ::* * *: : * ** : .: . :* : :. .... * .:.: * . .:. ::. :* * :. * .: . * : * : . : : :.::.. :.:: :: :: . .*. .: : .. . :: : : :*. : : .:... .: . :.:** . : : :: . :**:.. :. :. . : : .:* *: . * ** . .::: . . : *. * . : ..:. . . : .: . . :: :* * : .: * : .:* * * ::* : * : . :: : :. :: ", "identical_positions": 376, "similar_positions": 578, "identity": "18.95%" }, { "cls_id": "homologset.agr.MGI:1891430", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8BHK3-1", "uniprot_id": "S36A2_MOUSE", "id": "Q8BHK3-1", "name": "Proton-coupled amino acid transporter 2", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSVTKSARSPQV-----------ATPLNLDL---PESAKKLQSQDPSP---------------------------------------------------------------------ANGSSSESS--KKTKGITGFQTLVHLVKGNMGTGILGLPLAVKNAGILMGPLSLLVMGLIACHCMHILVRCAQRFCHRL-NKPFMDYGDTVMHGLAFSPNAWLQNHAHWGRRVVSFFLIVTQLGFCCVYIVFLADNLKQVVEAVNSTTISCHKNETVVLTPTMDSRLYMLSFLPVLGLLVFVRNLRVLTIFSLLANISMLVSLVIIAQYI----IQEIPDASQLP--LVASWKTYPLFFGTAIFSFESIGVVLPLENKMKDARGFP---TILSLGMSIITTLYIAIGALGYLRFGDDIKASITLNLP-NCWLYQSVKLLYVVGILCTYALQFYVPAEIIIPLAVSQVSK-----------------------RWALPVDLSIRLALVCLTCMLAILIPRLDLVLSLVGSVSSSALALIIPPLLEVVTYYG----EGISPLTVTKDALISILGFMGFVVGTYQALDELIKSGNSPALSNSTMFIQ-----------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8K415-1", "uniprot_id": "S36A2_RAT", "id": "Q8K415-1", "name": "Proton-coupled amino acid transporter 2", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSVTKSAGSPQV-----------AATVKLDLVSFPESAKKVQSQDPNP---------------------------------------------------------------------VNGSSSESS--EKTKGITGFQTLVHLVKGNMGTGILGLPLAVKNAGILMGPLSLLVMGLIACHCMHILVRCAQRFCHRL-NKPFMDYGDTVMHGLASSPNTWLQSHAHWGRHAVSFFLIVTQLGFCCVYIVFLADNLKQVVEAVNSTTISCHKNETVVLTPTIDSRLYMLAFLPVLGLLVFIRNLRVLTIFSLLANVSMLVSLVIIGQYI----IQGIPDPSQLP--LVASWKTYPLFFGTAIFSFESIGVVLPLENKMKDARRFP---TILSLGMSIITTLYIAIGALGYLRFGDDIKASITLNLP-NCWLYQSVKLLYVVGILCTHALQFYVPAEIIIPLAVSQVSK-----------------------RWALPVDLSIRLALVCVTCMLAILIPRLDLVLSLVGSVSSSALALIIPPLLEVTTYYG----EGMSPLTITKDALISILGFMGFVVGTYQALDELIRSGNSLPLSNSTMFIQ-----------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q495M3-1", "uniprot_id": "S36A2_HUMAN", "id": "Q495M3-1", "name": "Proton-coupled amino acid transporter 2", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSVTKSTEGPQG-----------AVAIKLDLMSPPESAKKLENKDSTF---------------------------------------------------------------------LDESPSESAGLKKTKGITVFQALIHLVKGNMGTGILGLPLAVKNAGILMGPLSLLVMGFIACHCMHILVKCAQRFCKRL-NKPFMDYGDTVMHGLEANPNAWLQNHAHWGRHIVSFFLIITQLGFCCVYIVFLADNLKQVVEAVNSTTNNCYSNETVILTPTMDSRLYMLSFLPFLVLLVLIRNLRILTIFSMLANISMLVSLVIIIQYI----TQEIPDPSRLP--LVASWKTYPLFFGTAIFSFESIGVVLPLENKMKNARHFP---AILSLGMSIVTSLYIGMAALGYLRFGDDIKASISLNLP-NCWLYQSVKLLYIAGILCTYALQFYVPAEIIIPFAISRVST-----------------------RWALPLDLSIRLVMVCLTCLLAILIPRLDLVISLVGSVSGTALALIIPPLLEVTTFYS----EGMSPLTIFKDALISILGFVGFVVGTYQALDELLKSEDSHPFSNSTTFVR-----------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VT04-1", "uniprot_id": "PATH_DROME", "id": "Q9VT04-1", "name": "Proton-coupled amino acid transporter-like protein pathetic", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------MVNIVDSGSK-------HAPQEMEQFLP----------GEGKVMYKIQPRKSDTEQALAGN---------------------------------------------------------------------------DFDPFALRDNPHPTTDNETLTHLLKASLGTGILGMPFAFMCSGLIMGIFSTIFTAFICTHCSYVLVKCGHKLYYRT-RRTKMTFAEIAEAAFQKGP-KWCRGFAPVAKFSILFGLFLTYFGTCSVYTVIVASNFEQLISYWTGTA--------------VSLRMLICIMLVPLILIAWVPNLKYLAPVSMVANVFMGLGLGITFYYL----VQDLP-PVEER-ESVV-WSTLPQFFSITIFAMEAIGVVMPLENNMKTPQSFLGICGVLSQGMSGVTLIYMLLGFLGYLRYGSATGESITLNLPIEEWPAQTVKVLISLAVYCTFGLQFFVCLEIIWDG-IKEKCK----------------------KRPTLV-NYVLRTVLVTAAVVLAVAVPTIGPFMGLIGAFCFSILGLIFPVVIELIVHWES--GFGKYNWILWKNAIITLCGIGALVFGTQAAIKDIVKAYSNNENVGE----------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "M9PEU1-1", "uniprot_id": "M9PEU1_DROME", "id": "M9PEU1-1", "name": "Amino acid transporter transmembrane domain-containing protein", "aln": "-----------------------------------------------------------------------------------------------------------------------MSTPENLNAPAGKPPLPPRREQLTEKGQSLSLSSFGGSAGNISGSGRKQHLSGAALARHKLKMSLKRGGPPPVATSGSGVMTTSLDQQKIPTVTAGYGENEKPKGGKGGQSKFIRSDMADVPVQQAAGSTLPLVISRKK----------------------------GDDSEDGNYNPFEHRKVEHPTSDLETFVHLLKGSLGSGILAMPMAFSHAGLWFGLVATFAVGTLCTYCVHILVKCAHILCRRR-KIPMMGFADVAEQAFLDGP-PALNRWSRFIRFMVNTFLVIDLLGCCCIYLVFVATNVEQVVRVYMETE--------------LSIRVWIMIVTAPLIFMCLVRNLKFLTPFSMIANILMFVGIVITFIYM----FSDIPAPVERP-GIVS-VTEWPLFFGTVIFALEGIGVVMSLENDMKNPSHFIGCPSVLNFGMGLVIALYTLVGFFGFLKYGPETQASITLNLPLEDKLAQSVKLMIAIAIFFTFTLQFYVPVTILWKG-LEHKIRP---------------------EKQNIS-EYGLRVFLVLLCGGIAVALPNLGPFISLIGAVCLSTLGMIVPATIELAVYHEDP-GYGRFNWRLWKNSGLILFGVVGFVAGTYVSIIEFHAEFSSGH--------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VTD7-1", "uniprot_id": "Q9VTD7_DROME", "id": "Q9VTD7-1", "name": "Amino acid transporter transmembrane domain-containing protein", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------MPVMTKNGHS-------NSAYVADHP--------------DKLELAEKGQKNKAVVAKDPD----------------------------------------------------------------------------YNPYHHRDVEHPTTNSETLFHLLKGSLGTGILAMPNAFRNSGYITGSIGTIVIGFICTFCIHQLVKAQYELCRRK-KMPSMNYPMVAETAMGEGP-KCFRVFAPYIGTVVNTFLLIYQLGTCCVYVVFVASNIKAIVDAVADTS--------------IDVRLCMIIILLPLILINWVRNLKYLAPFSTLANAITMVSFGIICYYI----FREPVTTEGKD-AFGK-PSNFPLFFGTVLFALEAIGVILPLENEMKTPQKFGGSCGVLNVSMVLIVFLYVGMGLFGYLNYGSAVLGSITLNMPEHEVLSMCVKGMLAFAIYITHGLACYVAIDITWNDYVAKRLGA---------------------QRNALFWEYAVRTGLVLITFLLAVAIPNLELFISLFGALCLSALGLAFPALIQICTHWYNTKGFAKV-WLVLSNFVLIIVGILGLVIGTYTSLKEIVLTFSE----------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VLM3-1", "uniprot_id": "Q9VLM3_DROME", "id": "Q9VLM3-1", "name": "Amino acid transporter transmembrane domain-containing protein", "aln": "-----------------------------------------------------------------------------------------------------------------------MEDLTPLTNLQQIPEGAPRKKKMTER------------QPLLLQSDASDYEGSRGSAARPVRSSPP------------DNTLVNVHSEDSLAASGSGDDEIG--------------------------------------------------------------------STDKSYNPTHHRDLEHPTSNFDTLVHLLKGNIGTGILAMPDAFKNAGLYVGLFGTMIMGAICTHCMHMLVNCSHELCRRF-QQPSLDFSEVAYCSFESGP-LGLRRYSMLARRIVTTFLFITQIGFCCVYFLFVALNIKDVMDHYYK----------------MPVQIYLLIMLGPMILLNLVRNLKYLTPVSLVAALLTVAGLAITFSYM----LVDLPDVHTVK-PVAT-WATLPLYFGTAIYAFEGIGVVLPLENNMRTPEDFGGTTGVLNTGMVIVACLYTAVGFFGYLKYGEHVEGSITLNLPQGDTLSQLVRISMAVAIFLSYTLQFYVPVNIVEPF-VRSHFDT---------------------TRAKDLSATVLRVVLVTFTFLLATCIPNLGSIISLVGAVSSSALALIAPPIIEVITFYNV--GYGRFNWMLWKDVLILIFGLCGFVFGTWASLAQILNDRTH----------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q4V5R4-1", "uniprot_id": "POLYP_DROME", "id": "Q4V5R4-1", "name": "Glutamate transporter polyphemus", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MEPKSQDQAP-------------NRDDPDLQTEPLTIAQSITSFYM--------------------------------------------------------------------------YNPYEKRSVEVPLTNCDAFISLLKCVIGTGILAMPLAFRCSGFVMGTVMSILLMILLTYSIHLLIADMTECCRRR-RVPQVSMPEAVRIAYEEGP-KWINCFGRAAGFMTTCVLVFGQFLLCTVYLVFVSKNFKEIGDHYIER---------------YNERYYVLVACLLLLPLFMIRRLKYLVPLNLISNFLLYAGFALIMYYL----FNGLPNINDRE-MVTPPVEWI-EFIAIAAFSLTAVGSMLVVEAHMAHPQSYLGLFGVLNLAVLFILLSNMFFGIIGYWRFGDNVHASITLNIPQDEILSQFIKVFIASGIFLSYPLNGFVVITVMFSDYENSEPR----------------------GRYRTLIEYVVRLLFLFLTGAVAIGVPNLAALTELEGAFSLSNLNLLCPALIDVFLNYN--VGYGRLMWKLIRDILLILIGLIFGIVGCTVALMQLIRDF---------------------QLTLNSM--------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q8IQF3-1", "uniprot_id": "Q8IQF3_DROME", "id": "Q8IQF3-1", "name": "Amino acid transporter transmembrane domain-containing protein", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MGDKGG------------------------------------------------------------------------------------------------------------------FDPYENRNVAHPISDIGAFFSLLKCVVGTGVMAIPLSFNYAGIVTGIILLVSVCFMLIHGMQMLIICMIECSRRM-QIGYATYPVAMVYSFDQGP-RFFKYISKAGRYIVDGVLAFSQFGVCVVYNVFVAATLKQLVDFYWVV---------------ADLRIYIAVIALCLIPPFQIRKLKYLVPFNILASILIYTGFSLMMYYL----FVDLPPITERN-ILFGRIDKIPLFFGIALFSITSVGVMLAVEATMAKPRHYLGWFGILDRAILLVIISYVTFGLMGYWRYGDETAGSISLNIPTDEVLSQVAKGFIAAAIFLTYPLAGFVIIDIIMNHFWNKNGD----------------------LPNAALKESILRACTVVLICITAIIAPNLGPLLSLVGALTISLLNLVFPALIEICLYYPPEYNYGKLKWVLVKDIFYVIVGILILVQGTVFSIKDMISEWGGGDTTTGGPETTAEETTANMSATLTTALTAAPPDALRFRFL", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9W056-1", "uniprot_id": "S36A_DROME", "id": "Q9W056-1", "name": "Proton-coupled amino acid transporter-like protein acs", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MNDDIKT---------------VTVYPTTLELTTPTKSANGSNDD--------------------------------------------------------------------------YDPHQHRELKNPTTNFQTFAHFLKASVGTGVLAMPSAFAHAGYVNGTLLTLIIGSLALYCLHILIKCMYILCKRQ-RVPYVSFSQAMNLGLKQGP-PWLRCLAPIAVPFVDGFLAFYHFGICCVYVVFIAESIKQLVDEYLVV---------------WDVRIHMCIIIVPLLLIYSIKNLKLLAPFSSAANLLLLVGFGIILYYI----FEELPPLSERD-PFVA-AGKLPTFFGTVLFALEAVGVILAIEENMATPKSFVGPCGILNSGMSIVLGLYVLLGFFGYWKYGNESEGSITLNIPQSEIPAQVVKVFFAITTWISYALQGYVTAHILWDKYLAKRFK----------------------ETRQTFYELIFRAIIVLLTFGCAVAIPDLSVFLSLVGSFCLSILGLIFPVLLQICVQYT--EGYGPFRIKLIINLLLLCFGIFGGVVGTYVSILDIIAVYK-----------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VTD5-1", "uniprot_id": "Q9VTD5_DROME", "id": "Q9VTD5-1", "name": "Amino acid transporter transmembrane domain-containing protein", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MRNTRRRRL-------------DQKLPFHQRLLGGVQNSFGSPLA--------------------------------------------------------------------------NEARLSSKKDNGMSDLEAFINVLKCGFGTGCLAMPYAFLNSGWLVGLICTFALGFFVLYAMHILLHHINNLGVQH-NMPMISYRKAVELSIRKGP-SIFHFLSKPFGYLVDILLCAYHFGVDCVYVVFIAKSLKHLGDMYLWV---------------WDERLYMALIASPLILTFLIRNLKSLVPFSIISNILLLTGYCVILNYL----FRDLPEFEHLH-AIQP-LRNFPIFFGTVLFSIESVGVILSLGRSMRKPESLMGTCGVLNQGMIVVISFYAVFGFFGYWRYGENTSNSILQNMPQNDILPKLATGIFALAIFFSYALQGYVTVDIIWRNYLEPELE----------------------DRYLRTVECLLRIALVIASVLVAIQYPDFGLLLSLVGSFCLAQLGLILPGIVDICLRYE--EDYGPGKIFLIRSMLFICMGLAGGVAGTVVTLQTLYARYPVVRG-------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VX84-1", "uniprot_id": "Q9VX84_DROME", "id": "Q9VX84-1", "name": "Amino acid transporter transmembrane domain-containing protein", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------MDAEAPNQLEKNQTATVPRQETAE-------------GGSTGETAVGGAAAKVTK---EQDHD------------------------------------------------------------------------AEYHPP-------TSYLETIVHLFKGNIGPGLFAMGDAFKNGGLLVAPLLTVVIAVVSIHCQHVLVTCSKKMRDLKGDSVCADYAQTVEQCFENGP-SKLRGWSRTMGRLVDIFICVTQLGFCCIYFVFISTNLKQILQAYDID---------------MNVHLVMLLAFVPVLLSSLITNLKWLTPVSMFANVCMILGLAITLYYA----LKDG-LPEVEERALWTNGSQLALFFGTAIFAFEGIALVMPLKNAMRKPHQFERPLGVLNVGMFLVSVMFMFAGSVGYMKWGEQVGGSLTLNLG-DTILAQAVKLMVSAGVLLGYPLQFFVAIQIMWPNAKQMCGIE---------------------GRS-LLGELGFRTFMVLVTLAIAEMVPALGLFISLIGALCSTALALVFPPVIELISRSE--LNKGPGIWICVKNLVILVLALLGFFTGSYESLKQIVKHFGEEEVH------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "M9PHT8-1", "uniprot_id": "M9PHT8_DROME", "id": "M9PHT8-1", "name": "Amino acid transporter transmembrane domain-containing protein", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------MPKRDLTVLHRYFSGRLFPARTQQQQSDQKAIEAAGEMGRTLEI---------TGRQNDKSLEKNPERFTKNVTEKGAD------------------------------------------------------------------------PENGDPVRRRGHETSELEAATHLFKGSVGAGLFAMGDCFKNGGLAGATILLPIIAVMCVHCERMLIRGSVLAVERTPGVDFLDYPETVEKCFEHGP-RPLRKMSRVMKLIVEMFLCVTQFGFCAIYFVFITENLHQVLQQNGIV---------------ISMSMVMLITLLPAMIPSLMTNLKYISPVSLFANVALLFGLIATLTIA----FSDGPMPSVGDRHLFTGGAQLALFFGTALFSYEGIALILPLRNSMRRPEKFSTRFGVLNSTMFFTTALFIFTGFVSYVRWGEEVAGSITLNLVVEEVFSQVVKVIAALGVFLGYPIQFFVMIKILWPPLKRSNNCT---------------------QKYPITSQVCLRFFMVMMTFGVALVVPKLNLFISLIGALCSTCLAFVIPVLIDFVTRAQ--VPKALGVWSYIKNILILTVAVLGIVTGTYQSIVEIVKEFK-----------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P50944-1", "uniprot_id": "AVT4_YEAST", "id": "P50944-1", "name": "Vacuolar amino acid transporter 4", "aln": "MVTNNGDGEHLGIRRNGNLRHPSN-NMKIPRRAQSTVLNSNPFYSRKYSMSTLTPRDICRSVDSRVFVDMSSPNFQTLEDPHRDEIINSVRLNYLNSSKRSSVSHGNEAIPRVNPTKNSSASTIAAANVD------SDDDETNLSSAGGDITHDIYKLVKAEDPKRLRRPRSMENVTPKIEHHTKLSSASGLN-VPGGFRREFIVNKKRQEHQLNDSASSDFTSHESDSINQSSPSSNQDIDKVPFLTRNFLEFLYVFGHFAGESFEDDFIPDSSNMMIRGEDERSALLSRPDHMKVLPSAKG--TTSTKKVFLILLKSFIGTGVLFLPNAFHNGGLFFSVSMLAFFGIYSYWCYYILVQAKSSCGVSS---------------FGDIG---LKLYGPWMRIIILFSLVITQVGFSGAYMIFTAKNLQAFLDNVFHV-------------GVLPLSYLMVFQTIIFIPLSFIRNISKLSLPSLLANFFIMAGLVIVIIFTAKRLFFDLMGTPAMGVVYGLNADRWTLFIGTAIFAFEGIGLIIPVQDSMRNPEKFP---LVLALVILTATILFISIATLGYLAYGSNVQTVILLNLPQSNIFVNLIQLFYSIAIMLSTPLQLFPAIKIIENKFFPKFTKIYVKHDDLTTRVELRPNSGKLNWKIKWLKNFIRSIIVIIVVSIAYFGSDNLDKFVSVIGSLACIPLVYIYPSMLHLRGNSLPETKGEFWRFKPMLDTILIFFGIASMLYTSYQSIFGV----------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P36062-1", "uniprot_id": "AVT3_YEAST", "id": "P36062-1", "name": "Vacuolar amino acid transporter 3", "aln": "MNGKEVSSGSGRTQSNNNKKNNNGGSTGISHASGSPLTDGNGGNSNGNSRSRSRSRKSSGTTGGLLKKPPLLVNNEAVHASVPDASHTSCNNGTLEVSINNPEPHVVDAVARHLIRNPSNSLQLQGGDITRDLYKWTNDHPSSPSQYQYPSQPALSTSIPSQAPSFSNRKRSMSFSAASIASSSHLNNNSEANGNPLAAIGLAPAPMTHEEIRAPGGFRRSFIIQKRRKHNVDAPIPN-------FFTRNFIEFLTLYGHFAGEDLSEEEEEEEE---TEEEPEEEALETESTQLVSREHGRHPHKSSTVKAVLLLLKSFVGTGVLFLPKAFHNGGWGFSALCLLSCALISYGCFVSLITTKDKVGVDG---------------YGDMG---RILYGPKMKFAILSSIALSQIGFSAAYTVFTATNLQVFSENFFHLK-----------PGSISLATYIFAQVLIFVPLSLTRNIAKLSGTALIADLFILLGLVYVYVYS---IYYIAVNGVASDTMLMFNKADWSLFIGTAIFTFEGIGLLIPIQESMKHPKHFR---PSLSAVMCIVAVIFISCGLLCYAAFGSDVKTVVLLNFPQDTSYTLTVQLLYALAILLSTPLQLFPAIRILENWTFPSN------------------ASGKYNPKVKWLKNYFRCAIVVLTSILAWVGANDLDKFVSLVGSFACIPLIYIYPPLLHYKASILSGTS----RARLLLDLIVIVFGVAVMAYTSWQTIKMWSQ--------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . ..* .*.* : : .. .* . *: . : . * :: : ... . : .: : : . ::. . :: .:. :: : * . * : . . : :* : *: : : : : : . : *:. * * :. . .. :: ", "identical_positions": 13, "similar_positions": 65, "identity": "1.62%" }, { "cls_id": "homologset.agr.MGI:1891433", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8TCT6-2", "uniprot_id": "SPPL3_HUMAN", "id": "Q8TCT6-2", "name": "Signal peptide peptidase-like 3", "aln": "---------MAEQTY--------------------SWAYS-LVDSSQVSTFLISILLIVYGSFRSLNMDFENQDKE--KDSNSSSGSFNGNSTN---------NSIQTIDSTQALFLPIGASVSLLVMFFFFDSVQVVFTICTAVLATIAFAFLLLPMCQYLTRPCSPQNKISFGCCGRFTAAELLSFSLSVMLVLIWVLTGHWLLMDALAMGLCVAMIAFVRLPSLKVSCLLLSGLLIYDVFWVFFSAYIFNSNVMVKVATQPADNPLDVLSRKLHLGPNVGRDVPRLSLPGKLVFPSSTGS-HFSMLGIGDIVMPGLLLCFVLRYDNYKKQASGDSCGAPGPANISGRMQKVSYFHCTLIGYFVGLLTATVASRIHRAAQPALLYLVPFTLLPLLTMAYLKGDLRRMWSEPFHSKSSSSRFLEV", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9CUS9-1", "uniprot_id": "SPPL3_MOUSE", "id": "Q9CUS9-1", "name": "Signal peptide peptidase-like 3", "aln": "---------MAEQTY--------------------SWAYS-LVDSSQVSTFLISILLIVYGSFRSLNMDFENQDKE--KDSNSSSGSFNGNSTN---------NSIQTIDSTQALFLPIGASVSLLVMFFFFDSVQVVFTICTAVLATIAFAFLLLPMCQYLTRPCSPQNKISFGCCGRFTAAELLSFSLSVMLVLIWVLTGHWLLMDALAMGLCVAMIAFVRLPSLKVSCLLLSGLLIYDVFWVFFSAYIFNSNVMVKVATQPADNPLDVLSRKLHLGPNVGRDVPRLSLPGKLVFPSSTGS-HFSMLGIGDIVMPGLLLCFVLRYDNYKKQASGDSCGAPGPANISGRMQKVSYFHCTLIGYFVGLLTATVASRIHRAAQPALLYLVPFTLLPLLTMAYLKGDLRRMWSEPFHSKSSSSRFLEV", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0ABK0LIZ0-1", "uniprot_id": "A0ABK0LIZ0_RAT", "id": "A0ABK0LIZ0-1", "name": "", "aln": "---------MAEQTY--------------------SWAYS-LVDSSQVSTFLISILLIVYGSFRSLNMDFENQDKE--KDSSSSSGPFNGSSTN---------NSIQTIDSTQALFLPIGASVSLLVMFFFFDSVQVVFTICTAVLATIAFAFLLLPMCQYLTRPCSPQNKISFGCCGRFTAAELLSFSLSVMLVLIWVLTGHWLLMDALAMGLCVAMIAFVRLPSLKVSCLLLSGLLIYDVFWVFFSAYIFNSNVMVKVATQPADNPLDVLSRKLHLGPNVGRDVPRLSLPGKLVFPSSTGS-HFSMLGIGDIVMPGLLLCFVLRYDNYKKQASGDSCGAPGPANISGRMQRVSYFHCTLIGYFVGLLTATVASRIHRAAQPALLYLVPFTLLPLLTMAYLKGDLRRMWSEPFHSKSSSSRFLEV", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q86P97-1", "uniprot_id": "SPPL_DROME", "id": "Q86P97-1", "name": "Signal peptide peptidase-like", "aln": "MSHGGAGGGLGAQTVGAGQLGGGAAAAGGGEYRELHWTVSSVMDSSRVSTCLISMLLIVYGSFRSLNIEQEAREREQKKRNESMTNLLTGEPVEKEPNLYFTADKFATLDTMHALCLPLGASISLLIMFFFFDSMQLLFAVCTAIIATVALAFLLLPMCQYIIRPCTDGKRFSFGFCGRFTAAELFSFTLSVSIVCIWVLTGHWLLMDAMGMGLCVAFIAFVRLPSLKVSTLLLTGLLIYDVFWVFLSSYIFSTNVMVKVATRPADNPVGIVARKLHLG-GIVRDTPKLNLPGKLVFPSLHNTGHFSMLGLGDVVMPGLLLCFVLRYDAYKKAQGVTSDPTLSPP--RGVGSRLTYFHCSLLGYFLGLLTATVSSEVFKAAQPALLYLVPFTLLPLLLMAYLKGDLRRMWSEPFIAQQPS-KQLEV", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :. ** *: * ::***:*** ***:************:: * :::* * ..* :. :.*...: :.: *:*: :** **:***:***:*******:*::*::***::**:*:**********: ***: :::*** *********:**:*** :* *************:.******:************ ***:***********:*:***.:********:*****:.:::****** .: **.*:*.********* .: ******:**:************** *** . * : .*. * .:::****:*:***:*******:*.:.:****************** **************** ::..* : ***", "identical_positions": 251, "similar_positions": 92, "identity": "58.92%" }, { "cls_id": "homologset.agr.MGI:1891434", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9WUJ3-1", "uniprot_id": "MYOME_RAT", "id": "Q9WUJ3-1", "name": "Myomegalin", "aln": "--------------------------------------------------------------MSNGYRTLSQHLNDLKKENFSLKLRIYFLEERMQQKYEVSRE--------------DVYKRNIELKVEVESLKRELQDRKQHLHKTWADEE-------------------------------------------------------DLNSQNEAELRRQVEEPQQETEHVYELLDNNIQLLQEESRFAKDEATQMETLVEAEKGCNLEL----SERWKDATKNREDAPGDQV---------KLDQYSAALAQRDRRIEELRQSLAAQEG------LVEQLSREKQQLLHLLEEPGGMEVQP----------------------MPKGLPTQQKPDLNETP------TTQPSVSDSHLAELQDKIQQTEVTNKILQEKLNDMSCELRSAQESSQKQDTTIQSLKEMLKSRESETEELYQVIEGQNDTMAKLPEMLHQSQLGQLQSSEGIAPAQQQVALLDLQSALFCSQLEIQKLQRLLRQKERQLADGKRCMQFVEAAAQEREQQKEAAWKHNQELRKALQHLQGELHSKSQQLHVLEAEKYNEIRTQGQNIQHLSHSLSHKEQLIQELQELLQYRDTTDKTLDTNEVFLEKLRQRIQDRAVALERVIDEKFSALEEKDKELRQLRLAVRDRDHDLERLRCVLSANEATMQSMESLLRARGLEVEQLIATCQNLQWLKEELETKFGHWQKEQESIIQQLQTSLHDRNKEVEDLSATLLHKLGPGQSEVAEELCQRLQRKERVLQDLLSDRNKQAMEHEMEVQGLLQSMGTREQERQAVAEKMVQAFMERNSELQALRQYLGGKELMAASQAFISNQPAGATSVGPHHGEQTDQGSTQMPSRDDSTSLTAREEASIPRSTLGDSDTVAGLEKELSNAKEELELMAKKERESQIELSALQSMMAVQEEELQVQAADLESLTRNIQIKEDLIKDLQMQLVDPEDMPAMERLTQEVLLLREKVASVEPQGQEGSENRRQQLLLMLEGLVDERSRLNEALQAERQLYSSLVKFHAQPETFERDRTLQVELEGAQVLRSRLEEVLGRSLERLSRLETLAAIGGATAGDETEDTSTQFTDSIEEEAAHNSHQQLIKVSLEKSLTTMETQNTCLQPPSPVGEDGNRHLQEEMLHLRAEIHQPLEEKRKAEAELKELKAQIEEAGFSSVSHIR-NTMLSLCLENAELKEQMGEAMSDGWEVEEDKEKGEVMVETVVAKGGLSEDSLQAEFRKVQGRLKSAYNIINLLKEQLVLRSSEGNTKEMPEFLVRLAREVDRMNMGLP-SSEKHQHQEQEN-MTARPGPRPQSLKLGTALSVDGYQLENKSQAQDSGHQPEFSLPGSTKHLRSQLAQCRQRYQDLQEKLLISEATVFAQANQLEKYRAILS-ESLVKQDSKQIQVDLQDLGYETCGRSENEAEREETTSPECEEHGNLKPVVLVEGLCSEQGYLDPVLVSSPVKNPWRTSQEARG-VQAQGTSDDSSLLRKDIRDLKAQLQNAYKVIQNLRSRVRSLSATSDYSSSLERPRKLRAVATLEGASPHSVTDEDEGLLSDGTGAFYPPGLQAKKNLENLIQRVSQLEAQLPKTGLEGKLAEELKSASWPGKYDSLIQDQARKTVISASENTKREKDLFSSHPTFERYVKSFEDLLRNNDLTTYLGQSFREQLSSRRSVTDRLTSKFSTKDHKSE-KEEAGLEPLALRLSRELQEKEKVIEVLQAKLDTR---FSSPPSSHAASDSHRSASSTSFLS-------DDIEACSDMDVASEYTHYEEKKPSPSN-----------------SAASASQGLKGEPRSSSISLPTPQNPPKE--ASQAQPGFHFNSIPKPASLSQAPMHFTVPSFMPFGPSGPPLLGCCETP-VVSLAEAQQELQMLQKQLGRSVS---IAPPTSTSTLLSNHTEASSPRYSNPAQPHSPARGTIELGRILEPG--YLGS-GQWDMMR---PQKGSISGELSSGSSMYQLNSKPTGADLLEEHLGEIRNLRQRLEESICVNDRLREQLQHRLSSTARENG--STSHFYSQGLESMPQLYNENRALREENQSLQTRLSHASRGHSQEVDHLREALLSSSSQLQELEKELEQQKAERRQLLEDLQEKQDEIVHFREERLSLQENNSRLQHKLALLQQQCEEKQQLSLSLQSELQIYESLYENPKKGLKAFSLDSCYQVPG--ELSCLVAEIRALRVQLEQSIQVNNRLRLQLEQQMDHGAGKASLSSCPVNQSFSAKAELANQQPPFQGSAASPPVRDVGLNSPPVVLPSNSCSVPGSDSAIISRTNN--GSDESAATKTPPKMEVDAADGPFASGHGRHVIGHVDDYDALQQQIGEGKLLIQKILSLTRPARSVPALDAQGTEAPGTKSVHELRSSARALNHSLEESASLLTMFWRAALPNSHGSVLVGEEGNLMEKELLDLRAQVSQQQQLLQSTAVRLKTANQRKKSMEQFIVSHLTRTHDVLKKARTNLEMKSFRALMCTPAL--------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q80YT7-1", "uniprot_id": "MYOME_MOUSE", "id": "Q80YT7-1", "name": "Myomegalin", "aln": "--------------------------------------------------------------MSNGYRTLSQHLNDLKKENFSLKLRIYFLEERMQQKYEVSRE--------------DVYKRNIELKVEVESLKRELQDRKQHLDKTWADAE-------------------------------------------------------DLNSQNEAELRRQVEERQQETEHVYELLGNKIQLLQEEPRLAKNEATEMETLVEAEKRCNLEL----SERWTNAAKNREDAAGDQE---------KPDQYSEALAQRDRRIEELRQSLAAQEG------LVEQLSQEKRQLLHLLEEPASMEVQP----------------------VPKGLPTQQKPDLHETP------TTQPPVSESHLAELQDKIQQTEATNKILQEKLNDLSCELKSAQESSQKQDTTIQSLKEMLKSRESETEELYQVIEGQNDTMAKLREMLHQSQLGQLHSSEGIAPAQQQVALLDLQSALFCSQLEIQRLQRLVRQKERQLADGKRCVQLVEAAAQEREHQKEAAWKHNQELRKALQHLQGELHSKSQQLHVLEAEKYNEIRTQGQNIQHLSHSLSHKEQLIQELQELLQYRDNADKTLDTNEVFLEKLRQRIQDRAVALERVIDEKFSALEEKDKELRQLRLAVRDRDHDLERLRCVLSANEATMQSMESLLRARGLEVEQLTATCQNLQWLKEELETKFGHWQKEQESIIQQLQTSLHDRNKEVEDLSATLLCKLGPGQSEVAEELCQRLQRKERMLQDLLSDRNKQAVEHEMEIQGLLQSMGTREQERQAAAEKMVQAFMERNSELQALRQYLGGKELMTSSQTFISNQPAGVTSIGPHHGEQTDQGSMQMPSRDDSTSLTAREEASIPRSTLGDSDTVAGLEKELSNAKEELELMAKKERESQMELSALQSMMAMQEEELQVQAADLESLTRNVQIKEDLIKDLQMQLVDPEDIPAMERLTQEVLLLREKVASVEPQGQEVSGNKRQQLLLMLEGLVDERSRLNEALQAERQLYSSLVKFHAQPENSERDGTLQVELEGAQVLRTRLEEVLGRSLERLSRLESLAAIGGG------------------------------------ELESVQAQ--------------------EMLHLRAEIHQHLEEKRKAEVELKELKAQIEEAGFSSVSHISRNTMLSLCLENAELKEQMGEAMSDGWEVEEDKEKGEVMLETVVAKGCLNENSLQAEFRKVQGKLKSAYNIINLLKEQLLLRSSEGNSKEMPELLVRLAREVDRMNTGLP-SLGKHQHQEQENTTTARPGSRPQSLPLGAALSVDGYQLENKSQAQDSGHQPEFSLPGSTKHLRSQLAQCRQRYQDLQEKLLISEATVFAQANQLEKYRAVFS-ESLVKQDSKQIQVDLQDLGYETCGRSENEAEREETTSPECEEHNNLRPVVLMEGLCSEQGYLDPVLVSPPAKKPLENKPGKQEEFRAHGTPDDSSLLRKDIRDLKAQLQNANKVIQNLRSRVRSLSATSDYSSSLERPRKLRAVATLEGASPHSVTDEDEGWLSDGTGAFYPPGLQAKKDLESLIQRVSQLEAQLPKTGLEGKLAEELRCASWPGKYDSLIQDQARELSYLRQKIREGRGICYLLTQHAKDTVKSFEDLLRSNDIDYYLGQSFREQLAQGGQLTERLTSKLSTKDHKSE-KEEAGLEPLALRLSRELQEKEKVIEVLQAKLDTR---SLSPPSSHAVSDSHRSASTTSFLS-------DDIEACSDMDVASEYTHYDEKKPSPSH-----------------SAASASQGLKGESSSSPISLPTPQNPPKE--ASQAHPGFHFHSIPKPASLSQTPMHSALPSFVPFSPSGPPLLGCCETP-MVSLAEAQQELQMLQKQLGESVS---IAPPASTSTLLSNQTEASSPHYINPAQPHTPTRSTIELGRILEPG--YLGSSGQWDMMR---PQKGSVSGELSSGSSMYQLNSKPTGADLLEEHLGEIRNLRQRLEESICVNDRLREQLQHRLSSTARENG--STSHFYSQGLESMPQLYNENRALREENQSLQTRLSHASRGHSQEVDHLREALLSSRSQLQELEKELEQQKAERQ-----------------------------------------------QLSLQSELQIYESLCENPKKALKAFSLDSCHQVPG--ELSCLVAEIRALRGQLEQSIEVNNRLRLQLEQQMDRGAGKASLGPIAVGQSFPDKAEPAN---LHQGSAASPPVRDVGLNSPAMVLPNSSCSAPGSDHAIVTRTNNELSSDDSAAMKNPPKLEVDATDGPFANKHGRHVIGHVDDYDALQQQIGEGKLLIQKILSLMRSARSIPGQEAQDTEAPGNISAHELRSSAKALNHALEESTSLLNMFWRAALPNTHGPVLVGKEGQLMEKELLDLRAQVSQQEQILQNTAARLKRANQRKKSMEQFIVSHLTRTHDVLKKARTNLEMKSFRALTCTPAL--------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q5VU43-1", "uniprot_id": "MYOME_HUMAN", "id": "Q5VU43-1", "name": "Myomegalin", "aln": "--------------------------------------------------------------MSNGYRTLSQHLNDLKKENFSLKLRIYFLEERMQQKYEASRE--------------DIYKRNIELKVEVESLKRELQDKKQHLDKTWADVE-------------------------------------------------------NLNSQNEAELRRQFEERQQETEHVYELLENKIQLLQEESRLAKNEAARMAALVEAEKECNLEL----SEKLKGVTKNWEDVPGDQV---------KPDQYTEALAQRDKRIEELNQSLAAQER------LVEQLSREKQQLLHLLEEPTSMEVQP----------------------MTEELLKQQKLNSHETT------ITQQSVSDSHLAELQEKIQQTEATNKILQEKLNEMSYELKCAQESSQKQDGTIQNLKETLKSRERETEELYQVIEGQNDTMAKLREMLHQSQLGQLHSSEGTSPAQQQVALLDLQSALFCSQLEIQKLQRVVRQKERQLADAKQCVQFVEAAAHESEQQKEASWKHNQELRKALQQLQEELQNKSQQLRAWEAEKYNEIRTQEQNIQHLNHSLSHKEQLLQEFRELLQYRDNSDKTLEANEMLLEKLRQRIHDKAVALERAIDEKFSALEEKEKELRQLRLAVRERDHDLERLRDVLSSNEATMQSMESLLRAKGLEVEQLSTTCQNLQWLKEEMETKFSRWQKEQESIIQQLQTSLHDRNKEVEDLSATLLCKLGPGQSEIAEELCQRLQRKERMLQDLLSDRNKQVLEHEMEIQGLLQSVSTREQESQAAAEKLVQALMERNSELQALRQYLGGRDSLMS-QAPISNQQAEVTPTG-RLGKQTDQGSMQIPSRDDSTSLTAKEDVSIPRSTLGDLDTVAGLEKELSNAKEELELMAKKERESQMELSALQSMMAVQEEELQVQAADMESLTRNIQIKEDLIKDLQMQLVDPEDIPAMERLTQEVLLLREKVASVESQGQEISGNRRQQLLLMLEGLVDERSRLNEALQAERQLYSSLVKFHAHPESSERDRTLQVELEGAQVLRSRLEEVLGRSLERLNRLETLAAIGGAAAGDDTEDTSTEFTDSIEEEAAHHSHQQLVKVALEKSLATVETQNPSFSPPSPMGGDSNRCLQEEMLHLRAEFHQHLEEKRKAEEELKELKAQIEEAGFSSVSHIR-NTMLSLCLENAELKEQMGEAMSDGWEIEEDKEKGEVMVETVVTKEGLSESSLQAEFRKLQGKLKNAHNIINLLKEQLVLSSKEGNSKLTPELLVHLTSTIERINTELVGSPGKHQHQEEGN-VTVRPFPRPQSLDLGATFTVDAHQLDNQSQPRDPGPQSAFSLPGSTQHLRSQLSQCKQRYQDLQEKLLLSEATVFAQANELEKYRVMLTGESLVKQDSKQIQVDLQDLGYETCGRSENEAEREETTSPECEEHNSLKEMVLMEGLCSEQGRRGSTLASSSERKPLENQLGKQEEFRVYGKSENILVLRKDIKDLKAQLQNANKVIQNLKSRVRSLSVTSDYSSSLERPRKLRAVGTLEGSSPHSVPDEDEGWLSDGTGAFYSPGLQAKKDLESLIQRVSQLEAQLPKNGLEEKLAEELRSASWPGKYDSLIQDQARELSYLRQKIREGRGICYLITRHAKDTVKSFEDLLRSNDIDYYLGQSFREQLAQGSQLTERLTSKLSTKDHKSE-KDQAGLEPLALRLSRELQEKEKVIEVLQAKLDAR---SLTPSSSHALSDSHRSPSSTSFLS-------DELEACSDMDIVSEYTHYEEKKASPSHSDSIHHSSHSAVLSSKPSSTSASQGAKAESNSNPISLPTPQNTPKE--ANQAHSGFHFHSIPKLASLPQAPLPSAPSSFLPFSPTGPLLLGCCETP-VVSLAEAQQELQMLQKQLGESAS---TVPPASTATLLSNDLEADSSYYLNSAQPHSPPRGTIELGRILEPG--YLGSSGKWDVMR---PQKGSVSGDLSSGSSVYQLNSKPTGADLLEEHLGEIRNLRQRLEESICINDRLREQLEHRLTSTARGRG--STSNFYSQGLESIPQLCNENRVLREDNRRLQAQLSHVSREHSQETESLREALLSSRSHLQELEKELEHQKVERQQLLEDLREKQQEVLHFREERLSLQENDSRLQHKLVLLQQQCEEKQQLFESLQSELQIYEALYGNSKKGLKAYSLDACHQIPLSSDLSHLVAEVRALRGQLEQSIQGNNCLRLQLQQQLESGAGKASLSPSSINQNFPASTDPGNKQLLLQDSAVSPPVRDVGMNSPALVFPSSASSTPGSETPIINRANG-LGLDTSPVMKTPPKLEGDATDGSFANKHGRHVIGHIDDYSALRQQIAEGKLLVKKIVSLVRSACSFPGLEAQGTEVLGSKGIHELRSSTSALHHALEESASLLTMFWRAALPSTHIPVLPGKVGESTERELLELRTKVSKQERLLQSTTEHLKNANQQKESMEQFIVSQLTRTHDVLKKARTNLEVKSLRALPCTPAL--------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M2B7P4-1", "uniprot_id": "A0A8M2B7P4_DANRE", "id": "A0A8M2B7P4-1", "name": "", "aln": "MMLDSKSKDVCRICARELYGNQRRWIFHPTAKLSLQVLLSYALGREMTRDGRGEFACSKCAFMLDRMYRFDTVIARVEALSLERMQKLLLEKDRLRQCISGLYRKNNTDELGVDGGATDATVVDFARLAEAEYSALLQEDLTYSVYESWAEQCPQEQIQDHQCPLHHADAASGPRPRKCKGCAALRVTDSDYEAVCKVPRKVGRSTSCGPSTRYSGSVQDNTEETVPSAPPPEPIENNQSCELKPVGVSPASSVESLDTAVDVTQESYLKLPLLESEEEQSVVRRPESKPGSVCGLDVALSLLKSCEYHPLQSQRGSRIPVLLKTNTTPMESPYPLLQVPHIEMECPLFPQLPDVPSSIQQELQLELAEMEDQWLDDYVQCKPSGLPKRLIEEQQCHLAEYENAAGQCVNELQKAQQQVQSLQTKIRDSEASNKKLQQKLRDMENELRSVREAACGQETTIQTLGDSLSTKDYEITDLQRVIEEQKELLCSLKQQNNHYQLQQQQVS-GVTPSHLQADLLDLQGSLFSAQLELQGLQRTQQQSQRREDDLTRANQRLQTDLQGAVQRHREAEKHNQDLLTALESARAKLLQTEEKWRDEGRQRENEVEEREKTIRELKTSLEHKERLVQDYSELVDGQKEPAGNRDN---LIQKLKQRIQERDRALERAVDEKFTCMEQKEDEMRKLQLLLREKERDLEKLRCVLSNNEETIMSLEMLLRGKGLELEQVCEAWRSAQGVHSEREESYMRSLRERDALISQLQTSLHTRTKEAEEMTAVLLSKVSVGAGEVAEELKSRLQLKERLFQELLSDRSRQTQEHHSQVQDLLNTISSREHYIKDSAGRVGQVMAEQTARLQELRKQLG-------------------------------------------------------------SANPELTQEDTQALMDELQMTLRREREAQTQLSILRATLASYQDQLQTQTSDLDALSRTASVKEEIIKDLQMQLVEPSDLPLVERLTQELQLLREKVESQEASCNNHKQALLDPLVSMETGQAVQP----------HADFGGFTSDDGEEEEDEEDCNSEFAGSGEDEKRSKRTAQSLVSLQSCDQHQGLRGCQDAVAEG---------------------------------------------------------------PGLAEVKQLVEQKRAVERELMELKSQLEKAGFSSLSQMR-KAFFTLRSQNEELKGLMNLQN-----VGQKSTSCGQLVDTVGAKGKERE-----------------------------------------------------------------------------------------------------------------SAREQTVQLKSDLAQVQQESRELQERLMVSEATVQAQAEQLKDYRELLT-ETSVQQDSKQVQVDIQDLGYETCGRSENEAEREDTSSPEFDDLELCTSLSYRD--AGSQWWAGPATHNSGKPE------------------HDVTYLQQLVEDLRGQLSRSQALIRSLQAQMRDCTPVGTPR---------KVNWGLDNSETQSTAEEDEGWQSSDGFGSLPRQPKQDRELQELVSRVTSLEEQLRKG---KGHADDGKNGNWPGKFDTLIQAQARELSHLRQKMREGRGMCHILTQHLGDTTKTFEELLRSNDIDYYMGQSFRDQLSQSISLAQRVSTKISGRDHSEVPDDKSGHELLAIRLSKELQQKDKLIESLRSKLDQQQPRSDTPTSSHAFSVATDQSDRTSFVSDDHGSTNEDLELCSELDAASEYGQEEAARSATDPRNNRG--------SVLSHPSNPPSITSSHSHKSTNTCPSIHCTPRRPLETQEQTGLTTVPLSNSIPFSASLHCPQMCSQPVFDPHVHPLRTRHPYGGGFSLAEVHQELQMLQRQLGNSYHGPQMKPLPAFPLGPHAQPDHSSLHPLSHHAFEQSPLNSQHTSPAMKSGSSLLESSAMWDMMYSPRPLRPGPYGDVSSGSSGYQSG--HTGTDLMEEHLREIRTLRRRLEDSIQTNDRLRQQLEERLAASARNGAGAAPTNIYIQGLDSVSQLSNEIRVLKEENHTLQNQLQQARTDGSKEMERLREAVLSVRGQLKQAELEADKWADQCRR-----------------------------------MQAQIRDQTQTVLQLKEEKQNSLDNSTRLQQEVNVLQQQLSECQCLVHTLQCELQVYKRVCGTAESNAGSGLTLTLDLRERESNIQLLEQQLRERLDLCMPHPS--ARKQLFHVDQSPSPPVRDTGFSSPASPAIKQHDPKPYKYSGAEG-------------------LEGEAPDGSFACRTGRHMISHVDDFSVLQQQLLEGKAVIRKMEAALQASTESHDLPEG--------YVRNLQVSTKTLKQILEETSSLLRMFWRAALPSTETSAQQLKKEQSLRKEVIALRCKLSEQEQLLRDTMENLRASSQTKDSMEQFIVNQLSRTRDVLKQARSNLEKNELKIASLGFTPLPSSSFSVSSTPSWSERDAVSGVSLKHASSPGWNFVKPHLQDQHKMMTAS", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * : :. : :: .:. :: : ::*::* . . * :: .*.* :* . : ::**: . .:: ...:: : ** .: : *: *: . ... : : *:. : . *:* **. ...:. *. .*. * :* :**. ** * :: :: * ::. * : :* : * .:: : :.: * :*: . * .: ::.:: .** **:::*.:** **:**.::. **:..:*:: *: ***.* : *.::: * :* :*** *:: :..* : :: ** * : * * :*:: *. *****.:**.:***:* *** :*.:*: * .:. * ::: : :::. : ****:* .**: : :* ...:: : :: **:. : :.*:.*. **.***:*:*: **:: :. . . : :::**:***::: ****.:****:.:*:*:.*:*:*:* :*::::***:** *** ** *: *:* ***.:***:**: : :. * ::.* * .: : :*::::*.******* *.**.*:::*.** *:. * .*:**** .*** ***::*:*****.:*. **. ::*.**:::.:**: : * :: *.: *:.:.** **: ** . ::: . :**:: ::***:* :** *:: :* :::**.*::*:::*:*. .:**::*********:*.*:* :******: ****** * *.. :: . : *: * * . : : :..:.. ... * *.* . :. .* : *:: **: .: : * . .. **.:* :*:** .* ** ***:*:*:*****:*:: :::::* :* *** *. : :.. . :::** :* * * .* :*:*:*:* :*. ::***:*::***** ***::*:.** ::: *: *:*****:***:******************:*:*** :: : : ...* ... .. : .: *:: :.**:.**..: :*:.*::::*. : .. :. *:.:..:*..:**** *.. . . : .::*:.*:.**:.** ** * *:: : ..****:*:*** ***: .: : . . .*:**:***.**: *:*****:**:. .:::*:::*:* :**.. .:::* * **:***:***:*:*:** *::*** : :*.**** * : ... ***:* :::* **::* .*** : : :.:.. .:.... .... ... : *: : .*:. .* :.*: .:.: .:. : * *.* * .****.:*******:***.* * .: . . : .* . . .. .: . . ::.* * * . **:* * : . *::***** ** . **:**:**** ***.**:***:** *****:**:.**:::** . :.:::* ***:*:.** ** *.*:*:*: ** :*.:. *:* : ****:** .:*:: * * :: : : .*:.* * . :: ::. . : . *. : : : *.. . * *:*.:: . . :. :. : .. ..: ******.*:.**. .. . * . :* :*.**.** ***:*.*:**:..*:**: *** :::*: : :.: . ::*: *: :*:: ***::*** ********.:. .. : : .:*:: ** ::*:*:::*:.* .*: :.* *.*******.:*:**:****:**:*** :.:: : ", "identical_positions": 615, "similar_positions": 721, "identity": "23.63%" }, { "cls_id": "homologset.agr.MGI:1891435", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9JJW3-1", "uniprot_id": "ATPMK_RAT", "id": "Q9JJW3-1", "name": "ATP synthase F(0) complex subunit k, mitochondrial", "aln": "MAGPESDGQFQFTGIKKYFNSYTLTGRMNCVLATYGGIALLVLYFKLRP---------------------------------------------------------------------------------------KKTP----------AVKAT-------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q78IK2-1", "uniprot_id": "ATPMK_MOUSE", "id": "Q78IK2-1", "name": "ATP synthase F(0) complex subunit k, mitochondrial", "aln": "MAGAESDGQFQFTGIKKYFNSYTLTGRMNCVLATYGGIALLVLYFKLRP---------------------------------------------------------------------------------------KKTP----------AVKAT-------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q96IX5-1", "uniprot_id": "ATPMK_HUMAN", "id": "Q96IX5-1", "name": "ATP synthase F(0) complex subunit k, mitochondrial", "aln": "MAGPESDAQYQFTGIKKYFNSYTLTGRMNCVLATYGSIALIVLYFKLRS---------------------------------------------------------------------------------------KKTP----------AVKAT-------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "H0WES8-1", "uniprot_id": "H0WES8_DANRE", "id": "H0WES8-1", "name": "", "aln": "MGGHDAGSQHQFTGIAKYFNSYTITGRRNCVLATYASIAAIILFFKLKP---------------------------------------------------------------------------------------KKQK----------AVTSS-------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VR92-1", "uniprot_id": "Q9VR92_DROME", "id": "Q9VR92-1", "name": "", "aln": "MAD----------GFKKYFNGTTINGRANVAKATYATLALLFIVYKLRRGSGKTGELASGKCSCESDHESSLNGDIGVYGADPDCSVCRERSERAMTEFDREQQRRAAGEDDNGCRDDPPPPPPPPTSGGSGSAPRRKCPCEEPQRRAEGAVKHSSHSSWARGQQIQPPNQYQQYKQPEAEQVRPASQVMGQVHDAFYRVLRGVVGAVLGNAAVNTSGTASDSPAQAAAVEVSRDELDEDERDDGQDDETPLKRRTAPRSCVPTGSQENASGQPEELGREQADDQPQAEEQAEYSAFSDGFTSGLSFTSDEK", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9W2U8-1", "uniprot_id": "Q9W2U8_DROME", "id": "Q9W2U8-1", "name": "", "aln": "MAGEGE----KLTGLSKIFNGTTMSGRANVAKATYAVMG-LLIAYQVLK-------------------------------------------------------------------------------------PKKK------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*.. *: * **. *:.** * . ***. :. :.: ::: :* ", "identical_positions": 13, "similar_positions": 17, "identity": "4.17%" }, { "cls_id": "homologset.agr.MGI:1891436", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0AB32TTK0-1", "uniprot_id": "A0AB32TTK0_DANRE", "id": "A0AB32TTK0-1", "name": "", "aln": "---MMEIAVGMLLN------ATGTHRGDDNRSSHQHLYQ------DEDCATFSIIQMKSRISN---SLLTSPKPMAT-------KISVALESDLRGLGSSRNQNFTLQKQSASGSTTKYFKQHRPSVLRKGNQPFPQACSAHDWVVDTVCKTE---------------------PDSEPSDAIPLYTGQSE----SR-----------IGAYASSPQPG--SPEYTGKHPYS---LSGDYLCVKGQCRWPGCSKSEDVFTEYGHFLRHLSTDHAPGDRSIGQLRMQKDRVQHMENQLTAERQKLQAMQLHLLDVKSTSEGGNIVEK--PAHLSGLLQPASS-------NDHYDCERAATEALTQGY------------------------WQISTSQVIPGIIPSFEYYKFTNMRPPFTYASMIRWAILKSPEKQLTLKEIYQWFTSMFFYFRHNTATWKNAVRHNLSLHKCFVRVEGRKGSVWTVDEEEFLRRKGQKLHRDHDMDWMAPFQLFP------LTPQGESYQM----------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0AC58G9P9-1", "uniprot_id": "A0AC58G9P9_DANRE", "id": "A0AC58G9P9-1", "name": "", "aln": "MKRTGQEDTGCQLKHKKTASHTGLERHEDGMSNNDNIFILRCWILNSANDTLYVGRFQLQISTGRQRLSTKAQEMPHCKRETDKKMSGREDEQQKILKEELDASPLLKQHASDQCVDETFSESVSPVQLSNTASSNNNSSVFKPPLRQVQRSADEQRMQFLQLLVQNSRSGQIRPSVLRSTALLLQGNESNPTAMSRRKDTGHSAQISIQAVAESSQHRKQSASFHFHSPVQSEIQRSSALFINGHCRWPGCEK---AFDDNTHFLRHLNRDHSTDDKTIAQWRVQQDLVHHMENQLIQEKQKLHAMQLHLRLFECISTYTGVAGG--WWRPLALNFPPLG-------EPDGRTERACDAPVQQEP------------------------WHIPPPHLLPDFVSSAEYYKCANIRPPYTYAFLIRWSILEAPDKQRTLNEIYNWFTRMFFYFRHSSPTWKNAVRHNLSLHKCFVRVDGKTGAVWTVDEEEFQKRKGQKIHRDYTLKWSTPFSHCPPYEASDVPIKAKDSQ-----------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9BZS1-1", "uniprot_id": "FOXP3_HUMAN", "id": "Q9BZS1-1", "name": "Forkhead box protein P3", "aln": "----MPNPRPGKPSAPSLALGPSPGASPSWRAAPKASDLLGARGPGGTFQGRDLRGGAHASSSSLNPMPPSQLQLPTLPLVMVAPSGARLGPLPHLQALLQDRPHFMHQLSTVDAHARTPVLQVHPLESPAMISLTPPTTATGVFSLKARPG---------------------LPPGINVASLEWVSREPA----------------LLCTFPNPSAPRKDSTLSAVP-------QSSYPLLANGVCKWPGCEK---VFEEPEDFLKHCQADHLLDEKGRAQCLLQREMVQSLEQQLVLEKEKLSAMQAHLAGKMALTKASSVASS--DKGSCCIVAAGSQGPVVPAWSGPREAPDS-LFAVRRHL------------------------WGSHGNSTFPEFLHNMDYFKFHNMRPPFTYATLIRWAILEAPEKQRTLNEIYHWFTRMFAFFRNHPATWKNAIRHNLSLHKCFVRVESEKGAVWTVDELEFRKKRSQRPSRCSNPTPGP--------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q99JB6-1", "uniprot_id": "FOXP3_MOUSE", "id": "Q99JB6-1", "name": "Forkhead box protein P3", "aln": "----MPNPRPAKPMAPSLALGPSPGVLPSWKTAPKGSELLGTRGSGGPFQGRDLRSGAHTSSS-LNPLPPSQLQLPTVPLVMVAPSGARLGPSPHLQALLQDRPHFMHQLSTVDAHAQTPVLQVRPLDNPAMISLPPPSAATGVFSLKARPG---------------------LPPGINVASLEWVSREPA----------------LLCTFPRSGTPRKDSNLLAAP-------QGSYPLLANGVCKWPGCEK---VFEEPEEFLKHCQADHLLDEKGKAQCLLQREVVQSLEQQLELEKEKLGAMQAHLAGKMALAKAPSVASM--DKSSCCIVATSTQGSVLPAWSAPREAPDGGLFAVRRHL------------------------WGSHGNSSFPEFFHNMDYFKYHNMRPPFTYATLIRWAILEAPERQRTLNEIYHWFTRMFAYFRNHPATWKNAIRHNLSLHKCFVRVESEKGAVWTVDEFEFRKKRSQRPNKCSNPCP----------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A0B4K6N2-1", "uniprot_id": "A0A0B4K6N2_DROME", "id": "A0A0B4K6N2-1", "name": "", "aln": "-----------------------MHRIHDDEYS------------EDAKESDFKSSIQKEISVKSRHQISIPDICSDAVKNNCFPPTGFLNNSITFASHVVKCSSPASSIDESSTAAQQHESNPHMHIQGQHMMAPVPDLGFYNVPEFISEQE----------------------KLMFSDAERFLRSKDN--------------------EVCNNDFSYMHDEFAMR-------KYYHPLFAHGICRWPGCEMD---LEDITSFVKHLNTEHGLDDRSTAQARVQMQVVSQLESHLQKERDRLQAMMHHLYLSKQLLSPTKIDRKDVPGREGKFCRSPLTVNSIGRPIRQTNSPSPLNLPMVNSTNLCSIKKRNHDKNTFSINGGLPYMLERAGLDVQQEIHRNREFYKNADVRPPFTYASLIRQAIIDSPDKQLTLNEIYNWFQNTFCYFRRNAATWKNAIRTNLSLHKCFVRYEDDFGSFWMVDDNEFVKRRHLSRGRPRKYEPSSSPNSCQSGNGVPTDKNPCDNCTQHCTSLPPGADNPLDSNNPNDLGRIGCLPYCGSDGLSKASKDYSNMDSGMIESNSHLTIDEYSTNMYESSANEHNR", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . * . . . . . : : * :* *:****. : : *::* . :* .:: .* :* : * :*.:* *:::* ** ** : : . .: . : . :::* ::***:*** :** :*:.:*::* **:***:** * :**. ..*****:* ********** :. *:.* **: ** ::: : ", "identical_positions": 66, "similar_positions": 66, "identity": "10.87%" }, { "cls_id": "homologset.agr.MGI:1891441", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I6GKN6-1", "uniprot_id": "A0A8I6GKN6_RAT", "id": "A0A8I6GKN6-1", "name": "", "aln": "----------------------------MEGNSFSSRMSSEHENTETFPFELIFQHFKRQKVAISNAIKNPFPFLEGLRDHELITAKMYEDLQDSYRALVRVQEVIYRALDKLEKIFSMKVLYEVFSNVNMEKYPDLQLIYQSFERVLPNGLCFQRSDGGDPNSQLSLEQGPNGSCSQATLTLSPFNHSFSDGWGSNDRLNSSLTHGNQSENHQLPGSPNHLVSSLEDGLSETVQTSRVRREATTSTTNNTNESARKCSTLLRSPGSVLEDACEFQVQLNNRDASPEPYSLQPSNEE--RAVQLNHDLQINPCSVRLVDIKKENISYSLDDNQQTQARTNENQGSEIIELSSDE-----------------------------------------------------------------------------DSNDEINLSEASTLILSKPETAHSRQPPTPRTYRRGDTSDTSSSSLDRRRKRTGHTIAVGNNPVLGRDGGRRRKKRERHGN----YLIRNIKIPMNASWKTAFGTRHSNPSSQQGRKRERYQSGQREGPEPFENKVKRVPAG----------------------------------------PRIHKDVNADFSSNELLVTCGKVVGTLYKEKLNQGIHVKSIQSTEGKWFTPLEFEIEGGYEKCKNWRQSIRCSGWPLKELIKRGELQDPP--RKTEMKETPPNSQQRKRKRKLKNLKACKVCGQRRRVRPCATCRKCYHKNCHIPPVEVQSGPWHCAFCKTRNQLRCQENQACHKESEVLKRKMSPEEQLKCELLLLTIYCCPKSGFFIRKPKKRKEDFPDLQEHMWLNKIKHRLNKKAYHSVQHFVGDMRLIFQNHSKFYKSRFKNLGVIVGNKFEKTFKSVFSIEDTSKQLQPSQHTVLLT", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q99388-1", "uniprot_id": "CSPRS_MOUSE", "id": "Q99388-1", "name": "Component of Sp100-rs", "aln": "----------------------------MEGSNGSPRMSTEQENTEMHLIECMLKHFKIQKVAISNAIRSTFPFLESLRDREFITGKMYEDLLDSCRSLVPVDKVIYRALEELEKKFDMTVLCKLFNEVNMEKYPDLNLLRRSFECGAKPALKTMNSSSEHCNISDWLR-------LEATLKASVYMVAFS--------ITTSLTIVIIA-----------IVS----------QSLQLRKECFN----------------------------PFVYGLHNRDLQSKLYPWLC-------------------CQKKLLP---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P23497-1", "uniprot_id": "SP100_HUMAN", "id": "P23497-1", "name": "Nuclear autoantigen Sp-100", "aln": "MAGGGGDLSTRRLNECISPVANEMNHLPAHSHDLQRMFTEDQGVDDRLLYDIVFKHFKRNKVEISNAIKKTFPFLEGLRDRDLITNKMFEDSQDSCRNLVPVQRVVYNVLSELEKTFNLPVLEALFSDVNMQEYPDLIHIYKGFENVIHDKLPLQESEEEEREERSGLQLSLEQGTGENSFRSLTWPPSGSPSHAGTTPPENGLSEHPCETEQINAKRKDTTSDKDDSLGSQQTNEQCAQKAEPTES------------------------CEQIAVQVNNGDAGREMPCPLPCDEESPEAELHNHGIQINSCSVRLVDIKKEKPFSNSKVECQAQARTHHNQASDIIVISSEDSEGSTDVDEPLEVFISAPRSEPVINNDNPLESNDEKEGQEATCSRPQIVPEPMDFRKLSTFRESFKKRVIGQDHDFSESSEEEAPAEASSGALRSKHGEKAPMTSRSTSTWRIPSRKRRFSSSDFSDLSNGEELQETCSSSLRRGSGSQPQEPENKKCSCVMCFPKGVPRSQEARTESSQASDMMDTMDVENNSTLEKHSGKRRKKRRHRSKVNGLQRGRKKDRPRKHLTLNNKVQKKRWQQRGRKANTRPLKRRRKRGPRIPKDENINFKQSELPVTCGEVKGTLYKERFKQGTSKKCIQSEDKKWFTPREFEIEGDRGASKNWKLSIRCGGYTLKVLMENKFLPEPPSTRKKRILESHNNTLVDPCEEHKKKNPDASVKFSEFLKKCSETWKTIFAK---------EKGKFEDMAKADKAHYEREMKTYIPPKGEKKKKFKDPNAPKRPPLAFFLFCSEYRPKIKGEHPGLSIDDVVKKLAGMWNNTAAADKQFYEKKAAKLKEKYKKDIAAYRAKGKPNSAKKRVVKAEKSKKKKEEEEDEEDEQEEENEEDDDK----", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .. . . :: :: : : :::*** :** *****:..*****.***:::** **:** ** * ** *:.*:*..*.:*** *.: ** :*.:***::**** : :.** * .*. . : *. : :: : : * ..*: . : :: . : ::* * : *. :*: ", "identical_positions": 58, "similar_positions": 64, "identity": "6.33%" }, { "cls_id": "homologset.agr.MGI:1891445", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9HAT8-1", "uniprot_id": "PELI2_HUMAN", "id": "Q9HAT8-1", "name": "E3 ubiquitin-protein ligase pellino homolog 2", "aln": "-------------------------------------------------MFSP------------GQEEHCAPNKEPVKYGELVVLG---YNGALPNGDRGRRKSRFALYKRPKANGVKPSTVHVISTPQASKAISCKGQHSISYTLSRNQTVVVEYTHDKDTDMFQVGRSTESPIDFVVTDTISGSQNTDEAQITQSTISRFACRIVCDRNEPYTARIFAAGFDSSKNIFLGEKAAKWKNPDGHMDGLTTNGVLVMHPRGGFTE-ESQPGVWREISVCGDVYTLRETRSAQQRGKLVESETNVLQDGSLIDLCGATLLWRTADGLFHTPTQKHIEALRQEINAARPQCPVGLNTLAFP-SINRKEVVEEKQPWAYLSCGHVHGYHNWGHRSDTEANERECPMCRTVGPYVPLWLGCEAGFYVDAGPPTHAFTPCGHVCSEKSAKYWSQIPLPHGTHAFHAACPFCATQLVGEQNCIKLIFQGPID", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8BST6-1", "uniprot_id": "PELI2_MOUSE", "id": "Q8BST6-1", "name": "E3 ubiquitin-protein ligase pellino homolog 2", "aln": "-------------------------------------------------MFSP------------GQEEPSAPNKEPVKYRELVVLG---YNGALPNGDRGRRKSRFALYKRTYASGVKPSTIHMVSTPQASKAISSRGHHSISYTLSRSQTVVVEYTHDKDTDMFQVGRSTESPIDFVVTDTVSGGQN-EDAQITQSTISRFACRIVCDRNEPYTARIFAAGFDSSKNIFLGEKAAKWKNPDGHMDGLTTNGVLVMHPQGGFTE-ESQPGVWREISVCGDVYTLRETRSAQQRGKLVESETNVLQDGSLIDLCGATLLWRTADGLFHAPTQKHIEALRQEINAARPQCPVGLNTLAFP-SINRKEVVEEKQPWAYLSCGHVHGYHSWGHRSDTEANERECPMCRTVGPYVPLWLGCEAGFYVDAGPPTHAFTPCGHVCSEKSAKYWSQIPLPHGTHAFHAACPFCATQLVGEQNCIKLIFQGPVD", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8I5YCN0-1", "uniprot_id": "A0A8I5YCN0_RAT", "id": "A0A8I5YCN0-1", "name": "E3 ubiquitin-protein ligase pellino homolog", "aln": "MKRVWVGEAESAGNSALEQLGFSAAGEGLFSLWMCRSGEPALLSSVERSVFRPTRVLMGGLRDTRGSDPPSPTSRDSGNSEKRVLITTSKYNGALPNGDRGRRKSRFALYKRTKANGVKPSTIHVVSTPQASKAISCKGQHSISYTLSRNQTVVVEYTHDNDTDMFQVGRSTESPIDFVVTDTVSGGQN-DDAQITQSTISRFACRIVCDRNEPYTARIFAAGFDSSKNIFLGEKAAKWKNPGGHMDGLTTNGVLVMHPRGGFTD-ESQPGVWREISVCGDVYTLRETRSAQQRGKLVESETNVLQDGSLIDLCGATLLWRTADGLFHAPTQKHIEALRQEINAARPQCPVGLNTLAFP-SINRKEVVEEKQPWAYLSCGHVHGYHSWGHRSDGEANERECPMCRTVGPYVPLWLGCEAGFYVDAGPPTHAFTPCGHVCSEKSAKYWSQIPLPHGTHAFHAACPFCATQLVGEQNCIKLIFQGPVD", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O77237-1", "uniprot_id": "PELI_DROME", "id": "O77237-1", "name": "Protein pellino", "aln": "------------------------------------------MVKRTDGTESP----------ILAEDGGDGHDKPRLRYGELVILG---YNGYLPQGDRGRRRSKFVLHKRTEASGVKRSKHYIVQSPQTSKAILDANQHSISYTLSRNQAVIVEYKEDTETDMFQVGRSSESPIDFVVMDTLPGDKK--DAKVMQSTISRFACRILVNRCEPAKARIFAAGFDSSRNIFLGEKATKWQDN-VEIDGLTTNGVLIMHPKGSFCGGNAKCGLWRECSVGGDVFSLRESRSAQQKGQPIYDECNILQDGTLIDLCGATLLWRSAEGLQHSPTKHDLEKLIDAINAGRPQCPVGLNTLVIPRKVNIGDQVN--QPYVYLNCGHVQGHHDWGQ--DENTGARRCPMCLELGPVVTLCMGLEPAFYVDVGAPTYAFNPCGHMATEKTVKYWANVEIPHGTNGFQAVCPFCATPLDGATGYIKLIFQDNLD", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * ..: .: . : *:: *** **:******:*:*.*:**. *.*** *. :::.:**:**** .:*********.*:*:***..*.:*********:******** **:.*.:: :*:: ***********: :* ** .***********:********:**:: .:*********:***:*.* ::: *:*** ** ***::***:*****:*: : .* *:****:************:*:** *:**::.:* * : ***.***********.:* .:* : *: **:.**.****:*:*.**: * ::. *.**** :** *.* :* *..****.*.**:**.****:.:**:.***::: :****:.*:*.****** * * . ******. :*", "identical_positions": 238, "similar_positions": 117, "identity": "48.97%" }, { "cls_id": "homologset.agr.MGI:1891456", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "G3V783-1", "uniprot_id": "G3V783_RAT", "id": "G3V783-1", "name": "Receptor-interacting serine/threonine-protein kinase 2", "aln": "MNGDAICSALPHIPYHKLADLHYLSRGASGTVSSARHADWRVRVAVKHLHIHTPLLDSERNDILREAEILHKARFSYILPILGICNEPEFLGIVTEYMPNGSLNELLHRKTEYPEIAWPLRFRILHEIALGVNYLHNMNPPLLHHDLKTQNILLDNEFHVKIADFGLSKWRMMSLSQSRSYKSAPEGGTIIYMPPENYEPGQKSRASVKHDIYSYAVIMWEVLSRKQPFEEVTNPLQIMYSVSQGHRPNTSEENLPFDIPHRGLMISLIQSGWAQNPDERPSFLKCLIELEPVLRTFEDITFLEAVIQLKKSKIQSASSTIHLCDKK-MDLSLNIPASHPPQEESCGSSLLSRNAGSPGTSRSLSAPQDKGFFHGGPQDCSSSKAYHCPGNHSWDGIISVSQEAAFCDRRASSCSLTVIRPLLVEKSSERPQPGIAQQWIQSKREAIVSQMTEACLNQSLDALLSRDLIMKEDYELISTKPTRTAKVRQLLDTSDIQGEEFARVIVQKLKDNKQMGLQPYPEVLLVSRTPSSNVLQNKTL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P58801-1", "uniprot_id": "RIPK2_MOUSE", "id": "P58801-1", "name": "Receptor-interacting serine/threonine-protein kinase 2", "aln": "MNGDAICSALPPIPYHKLADLHYLSRGASGTVSSARHADWRVRVAVKHLHIHTPLLDSERNDILREAEILHKARFSYILPILGICNEPEFLGIVTEYMPNGSLNELLHRKTEYPDIAWPLRFRILHEIALGVNYLHNMNPPLLHHDLKTQNILLDNEFHVKIADFGLSKWRMMSLSQSRSYKSAPEGGTIIYMPPENYEPGQKSRASVKHDIYSYAVIMWEVLSRKQPFEEVTNPLQIMYSVSQGHRPDTSEENLPFDIPHRGLMISLIQSGWAQNPDERPSFLKCLIELEPVLRTFEDITFLEAVIQLKKAKIQSSSSTIHLCDKK-MDLSLNIPANHPPQEESCGSSLLSRNTGSPGPSRSLSAPQDKGFLSGAPQDCSSLKAHHCPGNHSWDGIVSVPPGAAFCDRRASSCSLAVISPFLVEKGSERPPIGIAQQWIQSKREAIVSQMTEACLNQSLDALLSRDLIMKEDYELISTKPTRTSKVRQLLDTSDIQGEEFAKVVVQKLKDNKQLGLQPYPEVPVLSKAPPSNFPQNKSL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O43353-1", "uniprot_id": "RIPK2_HUMAN", "id": "O43353-1", "name": "Receptor-interacting serine/threonine-protein kinase 2", "aln": "MNGEAICSALPTIPYHKLADLRYLSRGASGTVSSARHADWRVQVAVKHLHIHTPLLDSERKDVLREAEILHKARFSYILPILGICNEPEFLGIVTEYMPNGSLNELLHRKTEYPDVAWPLRFRILHEIALGVNYLHNMTPPLLHHDLKTQNILLDNEFHVKIADFGLSKWRMMSLSQSRSSKSAPEGGTIIYMPPENYEPGQKSRASIKHDIYSYAVITWEVLSRKQPFEDVTNPLQIMYSVSQGHRPVINEESLPYDIPHRARMISLIESGWAQNPDERPSFLKCLIELEPVLRTFEEITFLEAVIQLKKTKLQSVSSAIHLCDKKKMELSLNIPVNHGPQEESCGSSQLHENSGSPETSRSLPAPQDNDFLSRKAQDCYFMKLHHCPGNHSWDSTISGSQRAAFCDHKTTPCSSAIINPLSTAGNSERLQPGIAQQWIQSKREDIVNQMTEACLNQSLDALLSRDLIMKEDYELVSTKPTRTSKVRQLLDTTDIQGEEFAKVIVQKLKDNKQMGLQPYPEILVVSRSPSLNLLQNKSM", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "***:******* *********:********************:*****************:*:***************************************************::**********************.***************************************** **************************:********** ***********:***************** .**.**:*****. *****:****************************:************:*:** **:******* *:******..* ********* * .*:*** .****.****:.*: .*** * :*********. :* . *****::::.** ::* *: . .*** ************ **.***************************:*******:********:********:*:*********:*******: ::*::*. *. ***::", "identical_positions": 445, "similar_positions": 60, "identity": "82.41%" }, { "cls_id": "homologset.agr.MGI:1891457", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D4ADZ0-1", "uniprot_id": "D4ADZ0_RAT", "id": "D4ADZ0-1", "name": "DNA polymerase eta", "aln": "-----------------MAPGQDLVVALVDMDCFFVQVEQRQNPHLRNKPCAVVQYKSWKGGGIIAVSYEARAFGVTRNMWADDAKKLCPDLLLAQVRESRG---------------------------KANLTKYREASVEVMEIMSHF-AVIERASIDEAYIDLTNAVQERLEKLQG----QPVSADLLPSTYIEGLPRGP-AVEDTVEKEDIRKQGLLQWLGSLEKDDPTSP----DLRLTVGAVIVEEMRAAIERKTGFQCSAGISHNKVLAKLACGLNKPNRQTLVSHGSVPQLFSQ--MPIRKIRSLGGKLGASVIDVLGVEYMGDLTQFTEAQLQSHFGEKNGSWLYAMCRGIEHEPVKPRQLPKTIGCSKNFPGKTALATREQVQWWLLQLALELEERLTKDRTDNGRVATQLVVSIRVEGDKRLSSLRRCCALTRYDAHKMSQDAFATIRNCNTSG----VQTEWSPPLTMLFLCATKFSASAP----------PACTDITVFLSSDSGCQPKVPAASSGTRTQEPGP--------------------------AAPTSKEAATSLESFFQKAAKRQRMRETSFVPPKVAVEK----SSSKPSLLFQTSGSPGTKSFFKQKSLLLQHTE---LSN-----------------AAAPCPPQ----ASSAVQPSRLPTDRADSRASCEEVCKP-VSSKA----------------------------------------------------------------------------------------------VSTEVNVAGNS-----SLAYNS-QEMTQRAA--------EDQVLCEKCDSLVPVWDMPEHLDYHFALELQKSFLQPCTSKPQAVP-VSPQGKRNPKSPLASSNKRLRPHG---MQTLESFFKPLTH", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9JJN0-1", "uniprot_id": "POLH_MOUSE", "id": "Q9JJN0-1", "name": "DNA polymerase eta", "aln": "-----------------MAPGQNRVVALVDMDCFFVQVEQRQNPHLRNKPCAVVQYKSWKGGGIIAVSYEARAFGVTRNMWADDAKKLCPDLLLAQVRESRG---------------------------KANLTKYREASVEVMEIMSYF-AVIERASIDEAYIDLTSAVQERLQKLQG----QPISADLLPSTYIEGLPRGP-TVEETVQKEAIRKQGLLQWLDSLQSDDPTSP----DLRLTVGAMIVEEMRAAIESKTGFQCSAGISHNKVLAKLACGLNKPNRQTLVSHGSVPQLFSQ--MPIRKIRSLGGKLGASVIEVLGIEYMGDLTQFTESQLQSHFGEKNGSWLYAMCRGIEHDPVKPRQLPKTIGCSKNFPGKTALATREQVQWWLLQLALELEERLTKDRNDNDRVATQLVVSIRFQGDRRLSSLRRCCALPRYDAHKMSQDAFAAIRNCNTSG----IQTEWSPPLTMLFLCATKFSAAAP----------PACTDITAFLSSDSSCQPKVPIASSETRTQGSGP--------------------------AVPTSKEAATSLASFFQKAAKKQRMKETSFVPLNTATEK----LSSKPSLVFQSSQTTGSQSFFKQKSLLLQHTQ---LSN-----------------SAAPDPPQ----ASPAAQPSCLPAECVDS-GPDDGAVKP-VSSKA----------------------------------------------------------------------------------------------VSTEMNVAGDSPNVLDSPAYNS-QEVTQRAT--------EDQVLCEKCDSLVPVWDMPEHTDYHFALELQKSFLQPCTSKPQAIPAVSPQGKRNPKSPSASSSKRLRPHG---MQTLESFFKPLTH", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9Y253-1", "uniprot_id": "POLH_HUMAN", "id": "Q9Y253-1", "name": "DNA polymerase eta", "aln": "-----------------MATGQDRVVALVDMDCFFVQVEQRQNPHLRNKPCAVVQYKSWKGGGIIAVSYEARAFGVTRSMWADDAKKLCPDLLLAQVRESRG---------------------------KANLTKYREASVEVMEIMSRF-AVIERASIDEAYVDLTSAVQERLQKLQG----QPISADLLPSTYIEGLPQGPTTAEETVQKEGMRKQGLFQWLDSLQIDNLTSP----DLQLTVGAVIVEEMRAAIERETGFQCSAGISHNKVLAKLACGLNKPNRQTLVSHGSVPQLFSQ--MPIRKIRSLGGKLGASVIEILGIEYMGELTQFTESQLQSHFGEKNGSWLYAMCRGIEHDPVKPRQLPKTIGCSKNFPGKTALATREQVQWWLLQLAQELEERLTKDRNDNDRVATQLVVSIRVQGDKRLSSLRRCCALTRYDAHKMSHDAFTVIKNCNTSG----IQTEWSPPLTMLFLCATKFSASAP----------SSSTDITSFLSSDPSSLPKVPVTSSEAKTQGSGP--------------------------AVTATKKATTSLESFFQKAAERQKVKEASLSSLTAPTQAPMSNSPSKPSLPFQTSQSTGTEPFFKQKSLLLKQKQ---LNN-----------------SSVSSPQQNPW-SNCKALPNSLPTEYPGCVPVCEGVSKLEESSKA----------------------------------------------------------------------------------------------TPAEMDLAHNSQSMHASSASKSVLEVTQKATPNPSLLAAEDQVPCEKCGSLVPVWDMPEHMDYHFALELQKSFLQPHSSNPQVVSAVSHQGKRNPKSPLACTNKRPRPEG---MQTLESFFKPLTH", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F1Q7Z9-1", "uniprot_id": "F1Q7Z9_DANRE", "id": "F1Q7Z9-1", "name": "DNA polymerase eta", "aln": "-----------------MDFGKERVVALVDMDCFYVQVEQRLKPELKNKPCVVAQYKTWKGGGIIAVSYEARAHGVGRNMFADDARKLCPDLQVARVPEAHG---------------------------KADLTHYREASVEVIEVMSRF-AVIERASIDEAYMDLTASVQERLKNTSV----QDITAQQLKNTHIQGFPTQQ--ENTHLDRDAQRAAGLQQWLDLLSSSTESSPA---DLRLAVGALIVEQMRAAVEEHTGFRCSAGISHNKVLAKLACGLNKPNRQTVLPLSSVPQLFST--LPISKIRNLGGKLGSSITETLSVENMGDLTRFSRAQLEQHFGDKTGPWLYDLCRGIEFEPVKPRQLPKSIGCSKNFAGKTCLRTKQQVQYWLHQLALELEERLNKDRDVNGRVARQLTVGVRQAGGQRSGSFSRCCALVRYDAMKMTNDSLTIIKSLNTAGA---HQEAWSPALTLLHLSASKFSDAPS----------SSSAGITGFLSSDAASSPSQSSSSQRSPMERPAQKRKRQ---------------------QDQRQRENTTSISAFFQRKSLEKQEIQNSLCPGDQSTSA----SGEHACGDTAAQKTTAISTFLQRESLEKQEIQNVSLDDE---------------DQSVCAPEENTCREKPAGISTSLQMKSLEKHQIQNSLCVGDQSVRAPGENPPREQTSDESPAGI--------------------------------------------------SSFFQMKSLEKHRIQNSPCTGDPNIRAPAENTSRDQTSERSTSGMSGCFQQAVAPAGERVCSPAEEDLQVCERCGMKVLVWEFPEHADYHFALDLQKSFSSGSPSQ--------------MKTPSGSQAKRARVQEP--RGTLHSFFKKT--", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VNX1-1", "uniprot_id": "POLH_DROME", "id": "Q9VNX1-1", "name": "DNA polymerase eta", "aln": "--------MSSARSHVSMQNKYDRVVLLVDMDCFFCQVEEKQHPEYRNRPLAVVQYNPWRGGGIIAVNYAARAKGVTRHMRGDEAKDLCPEIVLCQVPNIRE---------------------------KADTSKYRDAGKEVANVLQRFTQLLERASVDEAYLDITETVNHRMQQMQSGA--FALQPQELVNTFAVGYPSIGDYVNKITNRFANPYMDDERYQMSYDQNDLPAVRQS-DIRLLIGASVAGEVRAAVKKETGYECSAGIAHNKILAKLAAGMNKPNKQTILPLTETASLFDS--LPVGKIKGLGGKFGEVVCETLGIKFMGQVVKFSEVDLQRKFDEKNGTWLFNISRGIDLEAVTPRFYSKSIGCCKKFPGRNNITGLKTLQHWLGELSSEINDRLEKDFIENNRRAKHMVVQYVQDIDGEEVASSRSTALRDYDQESIVRLSLDLIKANTKTFLRPGSESALNNAIKFLGISVGKFETVSSGQNKLQEMFANQAAKKRRVSGDEPGQLPKVEMEKKQKQTDEFKMKSFFANYLQGAKKEDAKADGISANPLAAAAGAPNKNFVEEYKHKLHAAVRTEGTVLTSTPAEFKESFFSQYLKQQKKTGQQGSVTSREDSLDVQELAEELDAIEADNSKDFEEDTEEETELTSDTHMSKPEGQSSDAGQEQDPNTLNDSTGNDLYVETGIVPPTLTEDELKPSTSKRKFDEIESSVSNYKECYVEFAVPNLRTDILPTIKCDQCGANIPDEVKSLQTHRDHHFAQELSRTLRSTEREERTQSRQKISLKPTPPKKSKKTAGSGSSSYSTAPPSNSITKFFRAKPTQEQAPSDPQMNQCPECKAFIKCVDMPEHLDYHVARNLQRELNQQDLRTRTAALNKEKISPVQPKKQSQKKLNSTISASSSGTKTIAQFFSQSN-", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q04049-1", "uniprot_id": "POLH_YEAST", "id": "Q04049-1", "name": "DNA polymerase eta", "aln": "MSKFTWKELIQLGSPSKAYESSLACIAHIDMNAFFAQVEQMRCGLSKEDPVVCVQWN-----SIIAVSYAARKYGISRMDTIQEALKKCSNLIPIHTAVFKKGEDFWQYHDGCGSWVQDPAKQISVEDHKVSLEPYRRESRKALKIFKSACDLVERASIDEVFLDLGRICFNMLMFDNEYELTGDLKLKDALSNIREAFIGGNYDINSHLPLIPEKIKSLKFEGDVFNPEGRDLITDWDDVILALGSQVCKGIRDSIKDILGYTTSCGLSSTKNVCKLASNYKKPDAQTIVKNDCLLDFLDCGKFEITSFWTLGGVLGKELIDVLDLPHENSIKHIRET------------WPDNAGQLKEFLDAKVKQSDYDRSTSNIDPLKTADLAEKLFKLSRGRYGLPLSS----------RPVVKSMMSNKNLRGKSCNSIVDCISWLEVFCAELTSRIQDLEQEYNKIVIP------RTVSISLKTKSYEVYRKSGP-----------VAYKGINFQSHELLKVGIKFVTDLDIKGK-----------------------------------------NKSYYPLTKLSMTITNFDIIDLQKTVVD------MFGNQVHTFKSSAGKEDEEKTTSSKADEKT---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------PKLECCKYQVTFTDQKALQEHADYHLALKLSEGLNGAEESSKNLSFGEKRLLFSRKRPNSQHTATPQKKQVTS-SKNILSFFTRKK-", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : :**:.*: ***: :: * . .*:: .****.* ** *: * ::* . *.:: :. : *.. ** . :. :::. ::****:**.::*: . : . : . .. . : . . . *: * :*: : :* ::: *: *.*:: .* :.***.. :**: **:: .::. : : .: *** :* : : *.: ..: :: . * : : .. : . .: . :. : .: . . :.. * . : : . : . : .: : .. . .:.: . : . . . . : . . : : . : . .. . * : ** ***.* .*.. : : . .: .**. ", "identical_positions": 61, "similar_positions": 157, "identity": "6.59%" }, { "cls_id": "homologset.agr.MGI:1891463", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0ABK0LF67-1", "uniprot_id": "A0ABK0LF67_RAT", "id": "A0ABK0LF67-1", "name": "", "aln": "---------------MEAPPWEPVRNDSLPP----TLSPAVPPYVKLGLTAVYTAFYALLFVFIYAQLWLVLRYRHKRLSYQSVFLFLCLFWASLRTVLFSFYFRDFVAANSFSPFVFWLLYCFPVCLQFFTLTLMNLYFTQVIFKAKSKYSPELLKYRLPLYLASLFISLVFLLVNLTCAVLVKTGDWDRKVIVSVRVAINDTLFVLCAISLSICLYKISKMSLANIYLESKGSSVCQVTAIGVTVILLYTSRACYNLFILSFSQIKNVHSFDYDWYNVSDQVSRTQQGAAQGPDQWNVESCFNTGDQADLKSQLGDAGYIVFGVVLFVWELLPTTLVVYFFRVRNPTKDLTNPGMVPSHGFSPRSYFFDNPRRYDSDDDLAWNIAPQGLQGSFAPDYYDWGQQNNSFLAQAGTLQQDSTLDPDKASQG", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8BNQ3-1", "uniprot_id": "G137B_MOUSE", "id": "Q8BNQ3-1", "name": "Integral membrane protein GPR137B", "aln": "---------------MEAPPWEPVRNDSLPP----TLSPAVPPYVKLGLTAVYTVFYALLFVFIYAQLWLVLRYRHKRLSYQSVFLFLCLFWASLRTVLFSFYFRDFVAANSFSPFVFWLLYCFPVCLQFFTLTLMNLYFTQVIFKAKSKYSPELLKYRLPLYLASLFISLVFLLVNLTCAVLVKTGDWDRKVIVSVRVAINDTLFVLCAISLSICLYKISKMSLANIYLESKGSSVCQVTAIGVTVILLYTSRACYNLFILSFSQIKNVHSFDYDWYNVS--------------------------DQADLKSQLGDAGYVVFGVVLFVWELLPTTLVVYFFRVRNPTKDLTNPGMVPSHGFSPRSYFFDNPRRYDSDDDLAWNIAPQGLQGSFAPDYCDWGQQNNSFLAQAGTLHQDSTLDPDKASQG", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O60478-1", "uniprot_id": "G137B_HUMAN", "id": "O60478-1", "name": "Integral membrane protein GPR137B", "aln": "MRPERPRPRGSAPGPMETPPWDPARNDSLPP----TLTPAVPPYVKLGLTVVYTVFYALLFVFIYVQLWLVLRYRHKRLSYQSVFLFLCLFWASLRTVLFSFYFKDFVAANSLSPFVFWLLYCFPVCLQFFTLTLMNLYFTQVIFKAKSKYSPELLKYRLPLYLASLFISLVFLLVNLTCAVLVKTGNWERKVIVSVRVAINDTLFVLCAVSLSICLYKISKMSLANIYLESKGSSVCQVTAIGVTVILLYTSRACYNLFILSFSQNKSVHSFDYDWYNVS--------------------------DQADLKNQLGDAGYVLFGVVLFVWELLPTTLVVYFFRVRNPTKDLTNPGMVPSHGFSPRSYFFDNPRRYDSDDDLAWNIAPQGLQGGFAPDYYDWGQQTNSFLAQAGTL-QDSTLDPDKPSLG", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "E7F594-1", "uniprot_id": "G137B_DANRE", "id": "E7F594-1", "name": "G protein-coupled receptor 137Ba", "aln": "-----------------------MQKDSLP-----TLSPAVPPYVMLGLTVAYTIFYCLLFVFVYVQLWLVLRYRHKRFSYQTVFLFLCLLWAALRALLFSFYFKNCVTANTLGPFCFWLLYCFPVCLQFFTLSLMNLYFAQVIFKAKSKYSPELQKYRLPLYLLFLSISLLFLLVNLTCALLVKINRANTETVVLVRVTVNDSLFVLCAVSLSLCLYRIAKMSLANIYLEAKGTSVCQVTLIGVTVVLLYSSRACYNLVVLALTKIKSINSFDYDWYNVS--------------------------DQADLKSTLGDAGYVVFGVILFVWELLPTSLVVYFFRVRKPTLDRS-ASVIPGHMFSSRAYFFDNPRRYDSDDDLAWSIIPQNIQASFTSDSYDWSCRNNSFTAY--TEAEESHLAPEELNPY", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0ACD6B5S7-1", "uniprot_id": "A0ACD6B5S7_DANRE", "id": "A0ACD6B5S7-1", "name": "", "aln": "---------------MRAAVMESPPSNSSPPPPSSSLTPAVPPSVKLGLTALYTLFYCVLFIFVYAQLWLVLRYRHKRFSYQTAFLFLCLLWAALRALLFSFYFRDCGTANTLRPFCFWLLYCFPVCLQFFTLSLMNLYCAQVFFKAKSKFSPHLLRYKSPLYVLFFGVSLLFLLVNLSCALLVKMTDTPVKSVVLVRVAINDSLFVLCAVSLAVCLYKVAKMSIASIYLESKGTSVCQVTVIGLLVILLYSSRACYNLVVLSLTDVQSINSFDYDWYNVS--------------------------DQADLRSSLGDAGYVVFGVILFIWELLPTSLVVFFFRVRKPAQDRS-GSAIPSHVFSNRPYFFDNPRRYDSDDDLAWPSHPVTTSTSLSTDCSDWGSRSSSFLVHLGGDDQRSTVVTAGLNR-", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .:* * :*:***** * ****. ** **.:**:*:*.************:***:.******:**:**::******:: :**:: ** ****************:***** :**:******:**.* :*: ***: : :**:******:**:*** : :* ***::**:******:**::***:::***:*.****:**:****** **: *:***:*******.:*:::. :.::********** *****:. ******::***:**:******:***:*****:*: * : . :*.* ** *.***************** * . .::.* **. :..** . : * : . . ", "identical_positions": 223, "similar_positions": 92, "identity": "51.86%" }, { "cls_id": "homologset.agr.MGI:1891468", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9Z2H4-1", "uniprot_id": "LGR4_RAT", "id": "Q9Z2H4-1", "name": "Leucine-rich repeat-containing G protein-coupled receptor 4", "aln": "-------------MPGPLRLLCFFALGLLGSAGPSGAAPPLCAAPCSCDGDR-------------------------------------------------------------------------------------------------------------RVDCSGKGLTAVPEGLSAFTQALDISMNNITQLPEDAFKSFPFLEELQLAGNDLSFIHPKALSGLKELKVLTLQNNQLRTVPSEAIHGLSALQSLRLDANHITSVPEDSFEGLVQLRHLWLDDNSLTEVPVRPLSNLPTLQALTLALNNISSIPDFAFTNLSSLVVLHLHNNKIKSLSQHCFDGLDNLETLDLNYNNLDEFPQAIKALPSLKELGFHSNSISVIPDGAFGGNPLLRTIHLYDNPLSFVGNSAFHNLSDLHSLVIRGASLVQWFPNLTGTVHLESLTLTGTKISSIPDDLCQNQKMLRTLDLSYNNIRDLP------------------------SFNGCRALEEISLQRNQISLIKENTFQGLTSLRILDLSRNLIREIHSGAFAKLGTITNLDVSFNELTSFPTEGLNGLNQLKLVGNFKLKDALAARDFANLRSLSVPYAYQCCAFWGCDSYANLN-----------------------------------------------------------------------TEDNSPQEHSVTKEKGATDAANVTSTAENEEHSQIIIHCTPSTGAFKPCEYLLGSWMIRLTVWFIFLVALLFNLLVILTVFAS-CSSLPASKLFIGLISVSNLLMGIYTGILTFLDAVSWGRFAEFGIWWETGSGCKVAGSLAVFSSESAVFLLTLAAVERSVFAKDLMKHG--------KSSHLRQFQVAALLALLGAAVAGCFPLFHGGQYSASPLCLPFPTGETPS-LGFTVTLVLLNSLAFLLMAIIYTKLYCNLEKEDLSENSQSSVIKHVAWLIFTNCIFFCPVAFFSFAPLITAIS---ISPEIMKSVTLIFFPLPACLNPVLYVFFNPKFKEDWKLLKRR-------VTRKHGSVSVSISSQ----GGCGEQD----FYYDCGMYSHLQGN----------------------------------------------------------------LTVCDCCESFLLTKPVS---------CKHLIKSHSCPVLT--AASCQRPEAYWSDCGTQSAHSDYADEEDSFVS---DSSDQVQACGRACFYQSRGFP------------------------------------------LVRYAYNLQRVRD-------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A2ARI4-1", "uniprot_id": "LGR4_MOUSE", "id": "A2ARI4-1", "name": "Leucine-rich repeat-containing G protein-coupled receptor 4", "aln": "-------------MPGPLRLLCFFALGLLGSAGPSGAAPPLCAAPCSCDGDR-------------------------------------------------------------------------------------------------------------RVDCSGKGLTAVPEGLSAFTQALDISMNNITQLPEDAFKNFPFLEELQLAGNDLSFIHPKALSGLKELKVLTLQNNQLKTVPSEAIRGLSALQSLRLDANHITSVPEDSFEGLVQLRHLWLDDNILTEVPVRPLSNLPTLQALTLALNNISSIPDFAFTNLSSLVVLHLHNNKIKSLSQHCFDGLDNLETLDLNYNNLDEFPQAIKALPSLKELGFHSNSISVIPDGAFAGNPLLRTIHLYDNPLSFVGNSAFHNLSDLHSLVIRGASLVQWFPNLAGTVHLESLTLTGTKISSIPDDLCQNQKMLRTLDLSYNDIRDLP------------------------SFNGCRALEEISLQRNQISLIKETTFQGLTSLRILDLSRNLIREIHSGAFAKLGTITNLDVSFNELTSFPTEGLNGLNQLKLVGNFQLKDALAARDFANLRSLSVPYAYQCCAFWGCDSYANLN-----------------------------------------------------------------------TEDNSPQDHSVTKEKGATDAANATSTAESEEHSQIIIHCTPSTGAFKPCEYLLGSWMIRLTVWFIFLVALLFNLLVILTVFAS-CSSLPASKLFIGLISVSNLLMGIYTGILTFLDAVSWGRFAEFGIWWETGSGCKVAGSLAVFSSESAVFLLTLAAVERSVFAKDVMKNG--------KSSHLRQFQVAALVALLGAAIAGCFPLFHGGQYSASPLCLPFPTGETPS-LGFTVTLVLLNSLAFLLMAIIYTKLYCNLEKEDPSENSQSSMIKHVAWLIFTNCIFFCPVAFFSFAPLITAIS---ISPEIMKSVTLIFFPLPACLNPVLYVFFNPKFKDDWKLLKRR-------VTRKHGSVSVSISSQ----GGCGEQD----FYYDCGMYSHLQGN----------------------------------------------------------------LTVCDCCESFLLTKPVS---------CKHLIKSHSCPVLT--VASCQRPEAYWSDCGTQSAHSDYADEEDSFVS---DSSDQVQACGRACFYQSRGFP------------------------------------------LVRYAYNLPRVRD-------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9BXB1-1", "uniprot_id": "LGR4_HUMAN", "id": "Q9BXB1-1", "name": "Leucine-rich repeat-containing G protein-coupled receptor 4", "aln": "-------------MPGPLGLLCFLALGLLGSAGPSGAAPPLCAAPCSCDGDR-------------------------------------------------------------------------------------------------------------RVDCSGKGLTAVPEGLSAFTQALDISMNNITQLPEDAFKNFPFLEELQLAGNDLSFIHPKALSGLKELKVLTLQNNQLKTVPSEAIRGLSALQSLRLDANHITSVPEDSFEGLVQLRHLWLDDNSLTEVPVHPLSNLPTLQALTLALNKISSIPDFAFTNLSSLVVLHLHNNKIRSLSQHCFDGLDNLETLDLNYNNLGEFPQAIKALPSLKELGFHSNSISVIPDGAFDGNPLLRTIHLYDNPLSFVGNSAFHNLSDLHSLVIRGASMVQQFPNLTGTVHLESLTLTGTKISSIPNNLCQEQKMLRTLDLSYNNIRDLP------------------------SFNGCHALEEISLQRNQIYQIKEGTFQGLISLRILDLSRNLIHEIHSRAFATLGPITNLDVSFNELTSFPTEGLNGLNQLKLVGNFKLKEALAAKDFVNLRSLSVPYAYQCCAFWGCDSYANLN-----------------------------------------------------------------------TEDNSLQDHSVAQEKGTADAANVTSTLENEEHSQIIIHCTPSTGAFKPCEYLLGSWMIRLTVWFIFLVALFFNLLVILTTFAS-CTSLPSSKLFIGLISVSNLFMGIYTGILTFLDAVSWGRFAEFGIWWETGSGCKVAGFLAVFSSESAIFLLMLATVERSLSAKDIMKNG--------KSNHLKQFRVAALLAFLGATVAGCFPLFHRGEYSASPLCLPFPTGETPS-LGFTVTLVLLNSLAFLLMAVIYTKLYCNLEKEDLSENSQSSMIKHVAWLIFTNCIFFCPVAFFSFAPLITAIS---ISPEIMKSVTLIFFPLPACLNPVLYVFFNPKFKEDWKLLKRR-------VTKKSGSVSVSISSQ----GGCLEQD----FYYDCGMYSHLQGN----------------------------------------------------------------LTVCDCCESFLLTKPVS---------CKHLIKSHSCPALA--VASCQRPEGYWSDCGTQSAHSDYADEEDSFVS---DSSDQVQACGRACFYQSRGFP------------------------------------------LVRYAYNLPRVKD-------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "E7FE13-1", "uniprot_id": "LGR4_DANRE", "id": "E7FE13-1", "name": "Leucine-rich repeat-containing G protein-coupled receptor 4", "aln": "----------MALLAVRMLVLGLCVGGQAAAAGEGQSTPATCSPLCRCDEDG-------------------------------------------------------------------------------------------------------------GADCSGRGLTSVPTGLSAFTYYLDISMNNITELPANVFRNLPYLEELRLAGNDLAFIHPEALSGLHQLKVLMLQNNQLKTVPSAALKNLNALQSLRLDANHITSVPEDSFEGLQQLRHLWLDDNSLTEVPISPLQHQSNLQALTLALNRITHIPDNAFANLSSLVVLHLHNNRIQEIGKNCFNGLDNLETLDLNFNNLKIFPEAIQMLPKLKELGFHSNNIASIPEGAFCRNSLLRTIHLFDNPLSFVGTTAFQNLSDLHSLMLRGASMMQDFPSLTGTINLESLTLTGTKIRSIPADLCEDLTVLRTVDLSYNDIEDLP------------------------SFQGCVRLQDINLQHNQIKQIDRGTFQGMTSLRVLDLSRNQIKFIHRDAFLSLSALTNLDLSLNSLASVPTAGLSALNQLKLTGNMELRNGLMSKTLPKLRSITVPYAYQCCAFVAYDSAVNPA-----------------------------------------------------------------------EDD---------------ERRNAFGGEEDMERIPMVMHCSPLPGAFKPCEHLLGSWMIRLTVWFICLVALLFNCLVLAATFSPRTSSLSPSRFLVALLASANLLTGVYVAALTLLDTVTWGSFAEYGVWWETGAGCQVVGFLAVFSSEWAVLLLALAAVERCLAVRALMGKAGALRSRGERRERRRRFAIAALLLGLVSVAAACLSLYHG-SAMGSPLCLPFSEGSSPG-LGFTVALVLMNTLAYLLSAVVYTRLYCRLGRAQLADPEQAGSVRHIAWLIFTNCIFFCPVAAFSFAPLLAGTSNAVGGPEMAKSVTLIFFPLSACLNPVLYVCFSPSFRYDWLHLRGRG------RTGGCGRLVAKTVTKGTVAGGSPVSDDGEGLSSDCGMYTKLHGDS---------------------------------------------------------------RGMCEHCDAALHIRTSSSSGSSSSSACRHLVKSHSCPALMGNVPQCLSSEGYWPDTGTLSAQSEYGDEGDSFVS---DSSEQVQACGRACFCQSRGLP------------------------------------------LVHYSYNIPRMTD-------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q7KTA0-1", "uniprot_id": "Q7KTA0_DROME", "id": "Q7KTA0-1", "name": "", "aln": "MAARCRWSWRLALCPLLLQLLLQLLLLPPSAMGHDETKENPAPDMQNSQEQEPYVHLQHLQQQQQQNPQTVQQLSQITVNRTSKSASVTPTGIRENVMLPSADPEKEAQILYEKSLQEYHGSQLSTASTATDVIAGKRTLHSICERWLQKHCHCTGSLEVLRLSCRGIGILAVPVNLPNEVVVLDLGNNNLTKLEANSFFMAPNLEELTLSDNSIINMDPNAFYGLAKLKRLSLQNCGLKSLPPQSFQGLAQLTSLQLNGNALVSLDGDCLGHLQKLRTLRLEGNLFYRIPTNALAGLRTLEALNLGSNLLTIINDEDFPRMPNLIVLLLKRNQIMKISAGALKNLTALKVLELDDNLISSLPEGLSKLSQLQELSITSNRLRWINDTELPRS--MQMLDMRANPLSTISPGAFRGMSKLRKLILSDVRTLRSFPELEACHALEILKLDRAGIQEVPANLCRQTPRLKSLELKTNSLKRIPNLSSCRDLRLLDLSSNQIEKIQGKPFNGLKQLNDLLLSYNRIKALPQDAFQGIPKLQLLDLEGNEISYIHKEAFSGFTALEDLNLGNNIFPELPESGLRALLHLKTFNNPKLREFPPPDTFPRIQTLILSYAYHCCAFLPLVAMSSQKKTSQVQEAVLFPSDAEFDMTLWNNSMMNIWPQMHNLSKQLGASMHDPWETAINFNEEQLQTQTGGQIATSYMEEYFEEHDVSGPATGYGFGTGLFSGMSTEDFQPGSVQCLPMPGPFLPCADLFDWWTLRCGVWVVFLLSLLGNGTVVFVLLCS-RSKMDVPRFLVCNLAAADFFMGIYLGILAIVDAATLGEFRMFAIPWQMSVLCQLSGFLAVLSSELSVYTLAVITLERNYAITHAIHLN--------KRLSLKQAGYIMSVGWVFALIMALMPLVGVSDYRKFAVCLPFETTTGPASLTYVISLMFINGCAFLTLMGCYLKMYWAIRGSQAWNTNDSRIAKRMALLVFTDFLCWSPIAFFSITAIFGLQL---ISLEQAKIFTVFVLPLNSCCNPFLYAIMTKQFKKDCVTLCKHFEESRVVGGGGPGGRGAVARTKRGDLPPPLLPAAAVAHPPGCRCLRMLPSEMPNWHKMEQTPSMWQRLRTFCCGENRRRRKQRRQPQQRRQRAYTAAAANPYQYQFAELRQQRQNRASSISSENFCSSRSSS---WRHGPPSSAPVPPGNCSMPLKMLEPHAHPHGHGRRRHSAWLITRKTSQDSNLSSSRNDSSASATTASTSTFRLSRSSAGSSTPLPSIIAHNGKAQLDAVKPRLVRQEAVQEEEDSSPPRLGVRFLPTIPSAADSSVVMEDGDSANTGVASFLGMPLPGASSGFLIAPTTAATTSPPPVVLQPAKPPPDPNDAPL", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . : :* .: * . : .. .: : .* * *: :** .*. . **:. **:*:* : * * **** *:.*.: :.*:*: ** :** * *** *:::*. :::.* * **:*:.* :.*: *.: * :** * *:.* : .:* .* .*:**.*. * :: * * *..:..*:** *:.*:* .:. .:..* *:.*:*: * : :*:.:. *..*:**.: ** : * : : . :: :.: **** :. **:.:*.*:.*:: .. :: **.* . ** *.* : * .:* :**.: *::::*. *.:. :* .*:* *::: *. *:* : . :***: .*::***. * * ** ** : .: :*::. * :...* ** .* :** .* :*:: . : .:::: :.***:**** : . :: . . . : ::* * .*.* ** *:. * :* **.: *::*: * *: . :.. :.: .:::: :: :::: *:* . *:::*:.: * * :.: *: . *:: * ***:*** :: * : ::** : : :: : : : . :.* . .:**** *. * :.::*:::* *:* * ::* : : : .:: :::* *:**: : :.*:* **::.:: . * * .*::.:** :* **.**. :. .*: * * : * . :: .* * .: . .: :. * . : . .*. ...: : : .: ..: * *** .. :.. : * **. . *:: .: * ", "identical_positions": 218, "similar_positions": 332, "identity": "15.83%" }, { "cls_id": "homologset.agr.MGI:1891471", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0ABK0LAI2-1", "uniprot_id": "A0ABK0LAI2_RAT", "id": "A0ABK0LAI2-1", "name": "SPRY domain-containing SOCS box protein 3", "aln": "MMTPRTRTYFRILIQWSCEIFLIALPKANRNFGSGLTGCASLLTAVLSRETRPRAKLSDSPPSAAGPMQRGGGDCLRRDRNGKWVSPGGARWLQVLFTMARRARSSRAWHFVLSAARRDTDARAVALAGNSNWGYDSDGQHSDSDSDPEYSSLPPSIPSAVPVTGESFCDCEGQNEATFCNSLHTAHRGKDCRCGEEDEGECLAVGTCAGLGRFSGLEGSTLLCPSLVWAFYPTDFDWVWDDLNKSSATLLSCDNRKVSFHMEYSCGTAAIRGTKELGD-GQHFWEIKMTSPVYGTDMMVGIGTSDVDLDKYHHTFCSLLGRDEDSWGLSYTGLLHHKGDKTSFSSRFGQGSIIGVHLDTWHGTLTFFKNRKCIGVAATRLQNR---RFYPMVCSTAAKSSMKVIRSCASSTSLQYLCCYRLR--QLRPDSGDTLEGLP--------LPPGLKQVLHN-----KLGWVLSMNCSHWTSPAPPPGTAAPAAERDSRETRPCQRKRCRRS------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q571F5-1", "uniprot_id": "SPSB3_MOUSE", "id": "Q571F5-1", "name": "SPRY domain-containing SOCS box protein 3", "aln": "--------------------------------------------------------------------------------------------------MARRTRSSRAWHFVLSAARRDTDARAVALAGSSNWGYDSDGQHSDSDSDPEYSSLPPSIPSAVPVTGESFCDCEGQNEATFCNSLHTAHRGKDCRCGEEDE-----------------------------------DFDWVWDDLNKSSATLLSCDNRKVSFHMEYSCGTAAIRGTKELGD-GQHFWEIKMTSPVYGTDMMVGIGTSDVDLDKYHHTFCSLLGRDEDSWGLSYTGLLHHKGDKTSFSSRFGQGSIIGVHLDTWHGTLTFFKNRKCIGVAATRLQNR---RFYPMVCSTAAKSSMKVIRSCASSTSLQYLCCYRLR--QLRPNSGDTLEGLP--------LPPGLKQVLHN-----KLGWVLSMNCNHWKSPVPPPGTATPGAE--SLETRPCQRKRCRRS------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6PJ21-1", "uniprot_id": "SPSB3_HUMAN", "id": "Q6PJ21-1", "name": "SPRY domain-containing SOCS box protein 3", "aln": "--------------------------------------------------------------------------------------------------MARRPRNSRAWHFVLSAARRDADARAVALAGSTNWGYDSDGQHSDSDSDPEYSTLPPSIPSAVPVTGESFCDCAGQSEASFCSSLHSAHRGRDCRCGEEDE-----------------------------------YFDWVWDDLNKSSATLLSCDNRKVSFHMEYSCGTAAIRGTKELGE-GQHFWEIKMTSPVYGTDMMVGIGTSDVDLDKYRHTFCSLLGRDEDSWGLSYTGLLHHKGDKTSFSSRFGQGSIIGVHLDTWHGTLTFFKNRKCIGVAATKLQNK---RFYPMVCSTAARSSMKVTRSCASATSLQYLCCHRLR--QLRPDSGDTLEGLP--------LPPGLKQVLHN-----KLGWVLSMSCSRRKAPVSDP-QAATSAHPSSREPRPCQRKRCRRT------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VUW0-1", "uniprot_id": "Q9VUW0_DROME", "id": "Q9VUW0-1", "name": "B30.2/SPRY domain-containing protein", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------MLLPPYQEACNPGFCDCPFPNSIEVTNHKGHIPDLVRCQCGEDESG---------------------------------NVNAWRWHATDESDAVVT---DRDIIFHPTYSQGTAIVRGEQALKTNMVHFWEMRVITTLAGTDVMFGIGTESVNLGQFKFHFVSALGTNAQSWGFSYSGRIQHCGELLPYGQKFSQGCLIGVCLDRTRGHLEFYLNRRSLGVAYTNVPTDPDVKIYPMVCSTAAKSVIRLINCTSQPVTLQLRSFQALSRQPLKLAELRQMPGLKGIMQSYWFLAPPIRYSRNSRENELDLGDEAVLSSSKQRLRRKQKYRETDDAAVDEDDLYANAHKITLRSSDSGDEEHTASVHEMCDEYFHYLL", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :*. . . .**** .. . . *:***::. * *. ::*.*.: :*.: ** ** *** :** : * ****::: :.: ***:*.****..*:*.:::. * * ** : :***:**:* ::* *: .:..:*.**.:*** ** :* * *: **:.:*** *.: . ::*********:* ::: .. :...:** . * *: . : ** *.* :: :. .** :...: : * . : . :* *: ", "identical_positions": 90, "similar_positions": 97, "identity": "16.92%" }, { "cls_id": "homologset.agr.MGI:1891495", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9ET80-1", "uniprot_id": "JPH1_MOUSE", "id": "Q9ET80-1", "name": "Junctophilin-1", "aln": "MTGGRFDFDDGGTYCGGWEEGKAHGHGICTGPKGQGEYSGSWSHGFEVVGVYTWPSGNTYQGYWAQGKRHGLGVETKGKWMYRGEWSHGFKGRYGVRQSLCTPARYEGTWSNGLQDGYGVETYGDGGTYQGQWAGGMRHGYGVRQSVPYGMATVIRSPLRTSLASLRSEQSNGSVLHEAAAAAADSPAGTRGGFVLNFHADTELG-KKKGGLFRRGSLLGSMK-LRKSESKSSISSKRSSVRSDAAMSRISSSDANSTISFG--DVDCDFCPVEDHVDATTTETYMGEWKNDKRNGFGISERSNGMKYEGEWANNKRHGYGCTVFPDGSKEEGKYKNNILVRGIRKQLIPIRNTKTREKVDRAIEGAQRAAAMARTKVEIANSRTAHARAKADAADQAALAARQECDIARAVARELSPDFYQPGPDYIKQRCQEGGDIKENPEEKVLEKPPSPKESPHFYRKGTTPPRSPESSPK--------QSHSPQPSSPEPSKKQNPSPGARLSQDKQSLA-----EEQVTAFVNKPSMSKAPAKELGASV--SKYSGRHHVPNP---------------SNGELHSQYHGYYVKLNTPQHPPEDREDDR-GVSQSSSALVPRPSPNKWGPPKSVTKPVAKESKTEPKAKKSELAIPKNPASNDTCPSLEKEANSGPNSIMIVLVMLLNIGLAILFVHFLT", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D3ZQ55-1", "uniprot_id": "D3ZQ55_RAT", "id": "D3ZQ55-1", "name": "Junctophilin", "aln": "MTGGRFDFDDGGTYCGGWEEGKAHGHGICTGPKGQGEYSGSWSHGFEVVGGYTWPSGNTYQGYWAQGKRHGLGVETKGKWMYRGEWSHGFKGRYGVRQSLCTPARYEGTWSNGLQDGYGVETYGDGGTYQGQWAGGMRHGYGVRQSVPYGMATVIRSPLRTSLASLRSEQSNGSVLHEAAAAAADNPAGTRGGFVLNFHADTELG-KKKSGLFRRGSLLGSMK-LRKSESKSSISSKRSSVRSDAAMSRISSSDANSTISFG--DVDCDFCPVEDHVDATTTETYMGEWKNDKRNGFGISERSNGMKYEGEWANNKRHGYGCTVFPDGSKEEGKYKNNILVRGIRKQLIPIRNTKTREKVDRAIEGAQRAAAMARTKVEIANSRTAHARAKADAADQAAVAARQECDIARAVARELSPDFYQPGPDYIKQRFQEGVDIKENPEEKVPEKPPSPKESPHFYRKGTTPPRSPEASPK--------QSHSPQPSSPKSMKKQNPSSGARLSHDKRNTA-----EEQVVAIVNKPLMSKAPSKELGATV--SKYSGRHYVPNP---------------SNGELHSQYHGYYVKLNTPQHPPEDREDDS-GVGQSSSALVPRPSPNKWSPPKSVTKPVAKESKTEPKAKKSELAIPKNTASNDTCPPLEKEANSGPNSIMIVLVMLLNIGLAILFVHFLT", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9HDC5-1", "uniprot_id": "JPH1_HUMAN", "id": "Q9HDC5-1", "name": "Junctophilin-1", "aln": "MTGGRFDFDDGGTYCGGWEEGKAHGHGICTGPKGQGEYSGSWSHGFEVVGGYTWPSGNTYQGYWAQGKRHGLGVETKGKWMYRGEWSHGFKGRYGVRQSLCTPARYEGTWSNGLQDGYGVETYGDGGTYQGQWAGGMRHGYGVRQSVPYGMATVIRSPLRTSLASLRSEQSNGSVLHD-AAAAADSPAGTRGGFVLNFHADAELAGKKKGGLFRRGSLLGSMK-LRKSESKSSISSKRSSVRSDAAMSRISSSDANSTISFG--DVDCDFCPVEDHVDATTTETYMGEWKNDKRNGFGVSERSNGMKYEGEWANNKRHGYGCTVFPDGSKEEGKYKNNILVRGIRKQLIPIRHTKTREKVDRAIEGAQRAAAMARTKVEIANSRTAHARAKADAADQAALAARQECDIARAVARELSPDFYQPGPDYVKQRFQEGVDAKENPEEKVPEKPPTPKESPHFYRKGTTPPRSPEASPK--------HSHSP-ASSPKPLKKQNPSSGARLNQDKRSVA-----DEQVTAIVNKPLMSKAPTKEAGAVVPQSKYSGRHHIPNP---------------SNGELHSQYHGYYVKLNAPQHPPVDVEDGD-GSSQSSSALVHKPSANKWSPSKSVTKPVAKESKAEPKAKKSELAIPKNPASNDSCPALEKEANSGPNSIMIVLVMLLNIGLAILFVHFLT", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F1R2C3-1", "uniprot_id": "F1R2C3_DANRE", "id": "F1R2C3-1", "name": "Junctophilin", "aln": "MTGGRFDFDDGGTYCGGWEDGKAHGHGICTGPKGQGEYSGSWSHGFEVVGVYTWPSGNTYQGYWSQGKRHGLGVETKGKWLYRGEWSHGFKGRYGVRQSTNTPARYDGTWSNGLQDGYGVETYGDSGTYQGQWMGGMRHGYGVRQSVPYGMATIIRSPLRTSLASLRSVQSNGAVLQD---TVPDTPVGSRGGFVLNFHSDTEVVTGKKKGLFRRGSLFGSLRQLRKSDSKTSISSKRSSARSDATMSRISSSDANSTISYGEGEVPDDYTPMEDHVDATTTESYMGEWKNDKRNGFGVSERSNGLKYEGEWMNNKRHGYGCTIFPDGTKEEGKYKNNVLVRGIRKQLIPLKNHKTKEKVDRAVEGARRSAAIARTKVEIAVSRTSHARTKSEAADQAALAACQESDLARAVACELSPSFHQPGLEYIKQKFSEPVEEIKEEAPKEEEKKSS---GSPFYRRGTTPSHSPAQSPTPSPPRTSQKSQAQNPSISRKISKDNSVTARKISRDSTSVARKISKEERASIVAEITKVSVPPPPLPPPPPPAVQTIKLQDVPPPKPPKALEPVAKPAGTGNGQLHTAYHSYYVKPVKQLPPPEEPEDEEPEITQSSLARMPPPPKTLNTP---TPKPEVKIRKQESIKPKS-LAETKK-ASLDLVEEATVEE-SGPNSILVAMVMLLNIGLAIIFVHFLT", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*******************:****************************** *************:***************:****************** *****:******************.******* *******************:************** ****:**:: :..*.*.*:*********:*:*: ** ********:**:: ****:**:********.****:**************:* :* *: *:**********:**************:******:****** **********:****:*********:***********::: **:******:***:*:**:******** ***:***:*::******:** **.*:***** ****.*:*** :*:**: .* : :: * ** .: .. ***:****.:** **. :*:: .* .. .*:*. .. ::.:*. . * :*:. ..: . :* .*. . : : :* * .**:**: **.**** ** : ** *** * : *. . * ..** .* * *. ** ** .*: ** * * ******::.:**********:******", "identical_positions": 434, "similar_positions": 117, "identity": "62.45%" }, { "cls_id": "homologset.agr.MGI:1891496", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q2PS20-1", "uniprot_id": "JPH2_RAT", "id": "Q2PS20-1", "name": "Junctophilin-2", "aln": "MSGGRFDFDDGGAYCGGWEGGKAHGHGLCTGPKGQGEYSGSWNFGFEVAGVYTWPSGNTFEGYWSQGKRHGLGIETKGRWLYKGEWTHGFKGRYGIRQSTNSGAKYEGTWNNGLQDGYGTETYADGGTYQGQFTNGMRHGYGVRQSVPYGMAVVVRSPLRTSLSSLRSEHSNGTVAPDS---PAADGPTLPLPPVPRGGFALSLLATAEAARPP----GLFTRGALLGRLRRSESRTSLGSQRSRLSFLKSELSSGASDAASTGSLAEGAEGPDDAAAPFDADIDATTTETYMGEWKNDKRSGFGVSERSSGLRYEGEWLDNLRHGYGRTTLPDGHREEGKYRHNVLVKGTKRRVLPLKSNKVRQKVEHGVEGAQRAAAIARQKAEIAASRTSHAKAKAEAAEQAALAANQESNIARTLAKELAPDFYQPGPEYQKRRLLQEILENSESLLEPRERGPGTG-LPERPRESPQLHERETPQPEGGPPSPAGTPPQPKRPRPGSSKDGLLSPGAWNGEPGGEGSRPATPSDGAGRRSPARPASEHMAIEALQPPPAPSREPEVALYRGYHSYAVRTGPPEPPPLEDE----PEPEPEVPRSDSEPPSPVSATVQEEESPAPRSRVPAKPATLEPKPIVPKAEPKAKARKTEARGLSKAGAKKKGRKEVAQEAEAEVEVEEVPNTVLICMVILLNIGLAILFVHLLT", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9ET78-1", "uniprot_id": "JPH2_MOUSE", "id": "Q9ET78-1", "name": "Junctophilin-2", "aln": "MSGGRFDFDDGGAYCGGWEGGKAHGHGLCTGPKGQGEYSGSWNFGFEVAGVYTWPSGNTFEGYWSQGKRHGLGIETKGRWLYKGEWTHGFKGRYGIRQSTNSGAKYEGTWNNGLQDGYGTETYADGGTYQGQFTNGMRHGYGVRQSVPYGMAVVVRSPLRTSLSSLRSEHSNGTVAPDS---PAADGPMLPSPPVPRGGFALTLLATAEAARPQ----GLFTRGTLLGRLRRSESRTSLGSQRSRLSFLKSELSSGASDAASTGSLAEGAEGPDDAAAPFDADIDATTTETYMGEWKNDKRSGFGVSERSSGLRYEGEWLDNLRHGYGRTTLPDGHREEGKYRHNVLVKGTKRRVLPLKSSKVRQKVEHGVEGAQRAAAIARQKAEIAASRTSHAKAKAEAAEQAALAANQESNIARTLAKELAPDFYQPGPEYQKRRLLQEILENSESLLEPPERGLGTG-LPERPRESPQLHERETPQPEGGPPSPAGTPPQPKRPRPGASKDGLLSPGSWNGEPGGEGSRPATPSDGAGRRSPARPASEHMAIEALQPPPAPSQEPEVAMYRGYHSYAVRTGPPEPPPLEDEQEPEPEPEPEVRRSDSAPPSPVSATVPEEEPPAPRSPVPAKQATLEPKPIVPKAEPKAKARKTEARGLSKAGAKKKGRKEVAQAKEAEVEVEEVPNTVLICMVILLNIGLAILFVHLLT", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9BR39-1", "uniprot_id": "JPH2_HUMAN", "id": "Q9BR39-1", "name": "Junctophilin-2", "aln": "MSGGRFDFDDGGAYCGGWEGGKAHGHGLCTGPKGQGEYSGSWNFGFEVAGVYTWPSGNTFEGYWSQGKRHGLGIETKGRWLYKGEWTHGFKGRYGIRQSSSSGAKYEGTWNNGLQDGYGTETYADGGTYQGQFTNGMRHGYGVRQSVPYGMAVVVRSPLRTSLSSLRSEHSNGTVAPDSPASPASDGPALPSPAIPRGGFALSLLANAEAAARAPKGGGLFQRGALLGKLRRAESRTSVGSQRSRVSFLKSDLSSGASDAASTASLGEAAEG-ADEAAPFEADIDATTTETYMGEWKNDKRSGFGVSERSSGLRYEGEWLDNLRHGYGCTTLPDGHREEGKYRHNVLVKDTKRRMLQLKSNKVRQKVEHSVEGAQRAAAIARQKAEIAASRTSHAKAKAEAAEQAALAANQESNIARTLARELAPDFYQPGPEYQKRRLLQEILENSESLLEPPDRGAGAAGLPQPPRESPQLHERETPRPEGGSPSPAGTPPQPKRPRPGVSKDGLLSPGAWNGEPSGEGSRSVTPSEGAGRRSPARPATERMAIEALQAPPAPSREPEVALYQGYHSYAVRTTPPEPPPFEDQ------PEPEVSGSESAPSSPATAPLQAPTLRGP-EPARETPAKLEPKPIIPKAEPRAKARKTEARGLTKAGAKKKARKEAALAAEAEVEVEEVPNTILICMVILLNIGLAILFVHLLT", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "***************************************************************************************************:.****************************************************************************** **:*** ** *.:*******:***.**** *** **:***:***:*****:******:*****:***********.**.*.*** * ****:*********************************************** ********************.****:* ***.********.**************************************************:******************************** :** *:. **: *************:****.**************** *********:*****.*****..***:***********:*:*******.*****:*****:*:********* ******:**: ***** *:* *.**.:*.: .* . . . *.******:*****:***********:*******.***.* ************:*********************", "identical_positions": 599, "similar_positions": 58, "identity": "85.09%" }, { "cls_id": "homologset.agr.MGI:1891497", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZWH2-1", "uniprot_id": "D3ZWH2_RAT", "id": "D3ZWH2-1", "name": "Junctophilin", "aln": "MSSGGRFNFDDGGSYCGGWEDGKAHGHGVCTGPKGQGEYTGSWSHGFEVLGVYTWPSGNTYQGTWAQGKRHGIGLESKGKWVYKGEWTHGFKGRYGVRECTGNGAKYEGTWSNGLQDGYGTETYSDGGTYQGQWVGGMRQGYGVRQSVPYGMAAVIRSPLRTSINSLRSEHTNGAALHPDASPAVA----------GSPAVSRGGFVLVAHSDSEILKSKKKGLFRRSLLSGLKLRKSESKSSLASQRSKQSSFRSEAGMSTVSSTASDIHSTISLGEAEAELAVIEDDIDATTTETYVGEWKNDKRSGFGVSQRSDGLKYEGEWVSNRRHGYGCMTFPDGTKEEGKYKQNVLVSGKRKNLIPLRASKIREKVDRAVEAAERAATIAKQKAEIAASRTSHSRAKAEAALTAAQKAQEEARIARITAKEFSPSFQHRENGLEYQRPKHQMSCD-DIEVLSTGTPLQQESPELYRKGTTPSDLTPDDSPLQSFPASPTATPPPAPASRNKMAHFSRQVSVDEERSG--DIQMLLEGRGG----------DYARN-SWGEEK----AGASRGVRSGALRSGQP--TEDFRT---------------RGSGHK-------------QPGNPKPR--------------------------------ERRTESPTTFSWTSHHRAGNPCSGGPKLLQPD------------------------EEQLSNYKLEMKPLLR-----------------MDACPQDTH--------------------PQRRRHSRGAGGDRRSE---------------------DRGFGLQRLRSK-SQNKENLRPAS--SAEPTVQKLESLRLGDRPEPRLLRWDLTFSPPQKSLPVALESDEETGDELKSSTGSAPILVVMVILLNIGVAILFINFFI", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9ET77-1", "uniprot_id": "JPH3_MOUSE", "id": "Q9ET77-1", "name": "Junctophilin-3", "aln": "MSSGGRFNFDDGGSYCGGWEDGKAHGHGVCTGPKGQGEYTGSWSHGFEVLGVYTWPSGNTYQGTWAQGKRHGIGLESKGKWVYKGEWTHGFKGRYGVRECTGNGAKYEGTWSNGLQDGYGTETYSDGGTYQGQWVGGMRQGYGVRQSVPYGMAAVIRSPLRTSINSLRSEHTNGAALHPDASPAVA----------GSPAVSRGGFVLVAHSDSEILKSKKKGLFRRSLLSGLKLRKSESKSSLASQRSKQSSFRSEAGMSTVSSTASDIHSTISLGEAEAELAVIEDDIDATTTETYVGEWKNDKRSGFGVSQRSDGLKYEGEWVSNRRHGYGCMTFPDGTKEEGKYKQNVLVSGKRKNLIPLRASKIREKVDRAVEAAERAATIAKQKAEIAASRTSHSRAKAEAALTAAQKAQEEARIARITAKEFSPSFQHRENGLEYQRPKHQMSCD-DIEVLSTGTPLQQESPELYRKGTTPSDLTPDDSPLQSFPASPTSTPPPAPASRTKMAHFSRQVSVDEERSG--DIQMLLEGRGG----------DYARN-SWGEEK----AGASRGIRSGALRSGQP--TEDFRT---------------RGSGHK-------------QPGNPKPR--------------------------------ERRTESPTTFSWTSHHRAGNPCSGGPKLLEPD------------------------EEQLSNYKLEMKPLLR-----------------MDACPQDTH--------------------PQRRRHSRGAGGDR--------------------------GFGLQRLRSK-SQNKENLRPAS--SAEPTVQKLESLRLGDRPEPRLLRWDLTFSPPQKSLPVALESDEETGDELKSSTGSAPILVVMVILLNIGVAILFINFFI", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8WXH2-1", "uniprot_id": "JPH3_HUMAN", "id": "Q8WXH2-1", "name": "Junctophilin-3", "aln": "MSSGGRFNFDDGGSYCGGWEDGKAHGHGVCTGPKGQGEYTGSWSHGFEVLGVYTWPSGNTYQGTWAQGKRHGIGLESKGKWVYKGEWTHGFKGRYGVRECAGNGAKYEGTWSNGLQDGYGTETYSDGGTYQGQWVGGMRQGYGVRQSVPYGMAAVIRSPLRTSINSLRSEHTNGTALHPDASPAVA----------GSPAVSRGGFVLVAHSDSEILKSKKKGLFRRSLLSGLKLRKSESKSSLASQRSKQSSFRSEAGMSTVSSTASDIHSTISLGEAEAELAVIEDDIDATTTETYVGEWKNDKRSGFGVSQRSDGLKYEGEWASNRRHGYGCMTFPDGTKEEGKYKQNILVGGKRKNLIPLRASKIREKVDRAVEAAERAATIAKQKAEIAASRTSHSRAKAEAALTAAQKAQEEARIARITAKEFSPSFQHRENGLEYQRPKRQTSCD-DIEVLSTGTPLQQESPELYRKGTTPSDLTPDDSPLQSFPTSPAATPPPAPAARNKVAHFSRQVSVDEERGG--DIQMLLEGRAG----------DCARS-SWGEEQ----AGGSRGVRSGALRGGLL--VDDFRT---------------RGSGRK-------------QPGNPKPR--------------------------------ERRTESPPVFTWTSHHRASNHSPGGSRLLELQ------------------------EEKLSNYRMEMKPLLR-----------------METHPQKRR--------------------YSKGGACRGLGDDHRPE---------------------DRGFGVQRLRSK-AQNKENFRPAS--SAEPAVQKLASLRLGG-AEPRLLRWDLTFSPPQKSLPVALESDEENGDELKSSTGSAPILVVMVILLNIGVAILFINFFI", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A0R4IT36-1", "uniprot_id": "A0A0R4IT36_DANRE", "id": "A0A0R4IT36-1", "name": "Junctophilin", "aln": "MSTGGRFNFDDGGSYCGGWEEGKAHGHGICTGPKGQGEYAGSWSHGFEVVGIYTWPSGNTFQGTWAQGKRHGIGIENKGKWVYKGEWTHGFKGRYGVRESTGTSGKYEGTWNNGLQDGYGTETYSDGGTYQGQWVGGMRHGYGVRQSVPYGMAAVIRSPLRTSINSLRSEHSNGTALLTGDRAPVAGVGGSGVLVVGSPAVSRGGFVLTAHSEAELLKNKKKGLFRRSLLSGLKLRKSESKSSLASQRSKQSSFRSEAGMSTVSSAASDINSTISLGEGEGELPVGDDDVDATTTESYAGEWKNDKRTGCGVSRRSDGLQYQGEWLGNKRHGYGCTTFPDGTKEEGKYKQNILVSGKRKNLIPLRASKIREKVDRAVESADKAADIAKQKAEIALSRTAHARGKADAATAAAQKAQEECRLARITAKEFSPSFQHRGNRVECQRPKQQNSSENDVEVISSGT---ADSTELYMKGSTPPDLTPDVSPTPSRPSTPPRSPTTKSSHRTKNARFLRQTAVDEERGGTQEIQVLMEGRGGGGGGGSGGGGDYLRANSWSEEKRPSRGGSSRGGSRGSSRSTTPSVQDEVRVGAA------------RANGHK-------------HSSNHKPRDHSSSNHKT---------------------PRERRPDGP-SASWTSQRVHG-DSLAHSRLLEQD------------------------EEKLSNYEMEMRPLQP-----------------MDSHNSQKP--------------------YGHGEERHGHSETRAHM---------------------LQQRGKNRDRERDVRDASGHRDTREGPALDSVQKLDSLRVGEKLEARPLRRDLTLSPPQKSPPIALEHDDENQSQLKVNSGSNSILVVMVILLNIGVAILFVHFFI", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "E7F2R3-1", "uniprot_id": "E7F2R3_DANRE", "id": "E7F2R3-1", "name": "", "aln": "MSTGGRFDFDDGGSYCGGWEQGKAHGRGVCTGPQGQGEYAGAWSHGFEVLGVYTWPSGNSYKGTWAQGKRHGIGVESKGRWEYKGEWTQGFKGRYGKLESTSSGSRYEGTWSNGLQDGYGSETYSDGGTYQGQWLSGLRHGYGVRQSVPYGMAAIIFSPMCTSINSLRSDHSEGAPTPEDGSGVSG---------VSGSPVGRSGFVLCAHSEADRHR-KRKGRFRQSILSGLKLRRSESKSSLASQLSKQSSFCSEAGMSTVSSAASDINSNVSLGEAEA-----GGSVDATVTETYAGEWRNDMRTGWGVSHRSDGLHFEGEWFGNKRHGYGCTTFPDGTKEEGKYKQNVLVSGKRKNLIPLRTSKIREKVDRALEAAEKAADIAKQKAEIALSRMSHARGKAEAAEGVAQRALEECRLARAIAKELSPSFHHYGNGLECQRPKHHDRKEKDHEVVSTGT----DSPELCTPDTTPPVQTPDLSPVLSSPSSPPCSP---PTHRNRNACFMRQSAVDEQGGA--EIQVLVEGRGIDS--------TRAGANSWTAEMYP----HRRGSKGESSRSTTPSLLEEEISHINGHENSTHHPWENGSSNHKPIEHMAPEKVWDQMSSNQKPWKHVSLNQKTREHAISREREREHKPSNHNSVDCESSKFKPQVHIYSNHKSAGHNNLSNHKTNEHASTNHKPKEFISAHEKPHVSYHYNPQEHVSSYHKQHEHVHSNHKPRKSFTNHTIGEPSLNAYQLSDRGANNSTLEWTVENNSQWISSHSHPQEKEGENDYRVEMRFQPLDSLSQQNFGSGMKCSGLQGHNLQRLRQRNQEGKEWGLAARE-GSMDSVQMLDTLNVGVDVEEWPLHRDITLSPPLTSSLEPLEHEGEQLNLMKTNSGSSSVLVVMVILLNIGVAILFIHFFI", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "**:****:************:*****:*:****:*****:*:*******:*:*******:::************:*.**:* ******:******* *.:....:*****.********:*************:.*:*:**************:* **: ********:*::*:. . . ....*.*.**** ***::: : *:** **:*:*******:********** ****** **********:****:*.:****.*. ..:***.**:*.***:** *:* ***:*****:::*** .*:****** ***************:**.**********:**********:*:*::** ********* ** :*:*.**:** .**:* **.*:** ***:****:* * :* ****:: : * **:*:** :*.** .:**. *** ** * *::*. :* .: *.: * * ** :***: .. :**:*:***. ** * ** : *. :: ...:* ..* ** * * ::.:: . . : : :*::*.*. : . : ::: . : .* . : . :* *.: .. . : : :** * :*.:* * *: *:*:*** .* .** : * . :* .:** .:****************::***", "identical_positions": 393, "similar_positions": 179, "identity": "42.53%" }, { "cls_id": "homologset.agr.MGI:1891638", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P59895-1", "uniprot_id": "NEK6_RAT", "id": "P59895-1", "name": "Serine/threonine-protein kinase Nek6", "aln": "MAGQPSHMPHGGSPNHLCHVLGPAHPPDPQRHPNTLSFRCSLADFQIEKKIGRGQFSEVYKATCLLDRKTVALKKVQIFEMMDAKARQDCVKEIGLLKQLNHPNIIKYLDSFIEDNELNIVLELADAGDLSQMIKYFKKQKRLIPERTVWKYFVQLCSAVEHMHSRRVMHRDIKPANVFITATGIVKLGDLGLGRFFSSETTAAHSLVGTPYYMSPERIHENGYNFKSDIWSLGCLLYEMAALQSPFYGDKMNLFSLCQKIEQCDYPPLPGEHYSEKLRELVSMCIYPDPNHRPDIEYVHQVAKQMHVWTSST", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9ES70-1", "uniprot_id": "NEK6_MOUSE", "id": "Q9ES70-1", "name": "Serine/threonine-protein kinase Nek6", "aln": "MAGQPSHMPHGGSPNHLCHALGPAPPPDPQRLPNTLSFRCSLADFQIEKKIGRGQFSEVYKATCLLDRKTVALKKVQIFEMMDAKARQDCVKEIGLLKQLNHPNIIKYLDSFIEDNELNIVLELADAGDLSQMIKYFKKQKRLIPERTVWKYFVQLCSAVEHMHSRRVMHRDIKPANVFITATGIVKLGDLGLGRFFSSETTAAHSLVGTPYYMSPERIHENGYNFKSDIWSLGCLLYEMAALQSPFYGDKMNLFSLCQKIEQCDYPPLPGEHYSEKLRELVSMCIYPDPDHRPDIVYVHQVARQMHVWTSST", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9HC98-1", "uniprot_id": "NEK6_HUMAN", "id": "Q9HC98-1", "name": "Serine/threonine-protein kinase Nek6", "aln": "MAGQPGHMPHGGSSNNLCHTLGPVHPPDPQRHPNTLSFRCSLADFQIEKKIGRGQFSEVYKATCLLDRKTVALKKVQIFEMMDAKARQDCVKEIGLLKQLNHPNIIKYLDSFIEDNELNIVLELADAGDLSQMIKYFKKQKRLIPERTVWKYFVQLCSAVEHMHSRRVMHRDIKPANVFITATGVVKLGDLGLGRFFSSETTAAHSLVGTPYYMSPERIHENGYNFKSDIWSLGCLLYEMAALQSPFYGDKMNLFSLCQKIEQCDYPPLPGEHYSEKLRELVSMCICPDPHQRPDIGYVHQVAKQMHIWMSST", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*****.*******.*:***.***. ****** ********************************************************************************************************************************************************:***************************************************************************************************** ***.:**** ******:***:* ***", "identical_positions": 298, "similar_positions": 10, "identity": "95.21%" }, { "cls_id": "homologset.agr.MGI:1891640", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D4A864-1", "uniprot_id": "D4A864_RAT", "id": "D4A864-1", "name": "Polypeptide N-acetylgalactosaminyltransferase", "aln": "MRFFRRRHMPLRLAMLGSVFMLFLFIQQKDVSSREQ------------AMEKPWLKSLAGQKDHVLDLMLG---------------------AVNNIRDVMPKLQIRAPEPQQNPVSTNHSCLPGFYTPAELRPFWERPPQDPNSPGADGKAFQK-KEWTLLETQEKDEGYKKHCFNAFASDRISLQRSLGPDTRPPECVDQKFRRCPPLPTTSVVIVFHNEAWSTLLRTVYSVLHTSPAILLKEIILVDDASTDEHLKEKLERYVQQLQIVRVVRQQERKGLITARLLGASVAQAEVLTFLDAHCECFHGWLEPLLARIAEDKTAVVSPDIVTIDLNTFQFSKPMRRGKAHSRGNFDWSLTFGWEMLPEHEKQRRKDETYPIKSPTFAGGLFSISKAYFEHIGTYDNQMEIWGGENVEMSFRVWQCGGQLEIIPCSVVGHVFRTKSPHTFPKGTSVIARNQVRLAEVWMDDYKKIFYRRNLQAAKMAKENNFGDVSERLRLREQLHCHNFSWYLHNVYPEMFVPDLNPTFSGAIKNLGTS--QCLDVGE-NNRGGKPLIMYVCHNLGGNQYFEYTSQRDLRHNIGKQLCLHASGSTLGLRNCQFIGKNSEVPKDEEWELTQDQLIRNLGSGTCLTSKDKKPAMAPCNPSDPYQLWLFV-------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8C7U7-1", "uniprot_id": "GALT6_MOUSE", "id": "Q8C7U7-1", "name": "Polypeptide N-acetylgalactosaminyltransferase 6", "aln": "MRLLRRRHMSLRLAMLGSVFMLFLFIRQKDVSNQEQ------------AMEKPWLKSLAGQKDQVLDFMLG---------------------AVNNIRDVMPKLQIRAPEPPQTLVSTNHSCLPGFYTPAELKPFWDRPPQDPNSPGADGKAFQK-KEWTNLETKEKEEGYKKHCFNAFASDRISLQRSLGPDTRPPECVDQKFRRCPPLPTTSVIIVFHNEAWSTLLRTVYSVLHTSPAILLKEIILVDDASTDEHLKERLEQYVQQLQIVRVVRQRERKGLITARLLGASVAQAEVLTFLDAHCECFHGWLEPLLARIAEDKTAVVSPDIVTIDLNTFQFSRPVQRGKAHSRGNFDWSLTFGWEMLPEHEKQRRKDETYPIKSPTFAGGLFSISKAYFEHIGTYDNQMEIWGGENVEMSFRVWQCGGQLEIIPCSVVGHVFRTKSPHTFPKGTSVIARNQVRLAEVWMDDYKKIFYRRNLQAAKMVQENNFGDISERLRLREQLRCHNFSWYLHNVYPEMFVPDLNPTFYGAIKNLGTN--QCLDVGE-NNRGGKPLIMYVCHNLGGNQYFEYTSQRDLRHNIGKQLCLHASGSTLGLRSCQFVGKNSRVPKDEEWELTQDQLIRNSGSGTCLTSQDKKPAMAPCNPRDPYQLWLFV-------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8NCL4-1", "uniprot_id": "GALT6_HUMAN", "id": "Q8NCL4-1", "name": "Polypeptide N-acetylgalactosaminyltransferase 6", "aln": "MRLLRRRHMPLRLAMVGCAFVLFLFLLHRDVSSREE------------ATEKPWLKSLVSRKDHVLDLMLE---------------------AMNNLRDSMPKLQIRAPEAQQTLFSINQSCLPGFYTPAELKPFWERPPQDPNAPGADGKAFQK-SKWTPLETQEKEEGYKKHCFNAFASDRISLQRSLGPDTRPPECVDQKFRRCPPLATTSVIIVFHNEAWSTLLRTVYSVLHTTPAILLKEIILVDDASTEEHLKEKLEQYVKQLQVVRVVRQEERKGLITARLLGASVAQAEVLTFLDAHCECFHGWLEPLLARIAEDKTVVVSPDIVTIDLNTFEFAKPVQRGRVHSRGNFDWSLTFGWETLPPHEKQRRKDETYPIKSPTFAGGLFSISKSYFEHIGTYDNQMEIWGGENVEMSFRVWQCGGQLEIIPCSVVGHVFRTKSPHTFPKGTSVIARNQVRLAEVWMDSYKKIFYRRNLQAAKMAQEKSFGDISERLQLREQLHCHNFSWYLHNVYPEMFVPDLTPTFYGAIKNLGTN--QCLDVGE-NNRGGKPLIMYSCHGLGGNQYFEYTTQRDLRHNIAKQLCLHVSKGALGLGSCHFTGKNSQVPKDEEWELAQDQLIRNSGSGTCLTSQDKKPAMAPCNPSDPHQLWLFV-------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8MRC9-1", "uniprot_id": "GALT9_DROME", "id": "Q8MRC9-1", "name": "Putative polypeptide N-acetylgalactosaminyltransferase 9", "aln": "MAFIWRRRSTTIVKLVAFALAIWFCIAFLVYTDDTRRRAAQEGAGASGAGSAPGVGGGAGGLGDPIALALRNEPAGEDFGINGNVIGGGGQKQAHDEADIPPTVGKHKADLQAERMRKKAAEQPKKKPQEDSKKVIDPPANFEENPGELGKPVRLPKEMSDEMKKAVDDGWTKNAFNQYVSDLISVHRTL-PDPRDAWCKDEARYLTN-LPKTDVIICFHNEAWTVLLRTVHSVLDRSPEHLIGKIILVDDYSDMPHLKRQLEDYFAAYPKVQIIRGQKREGLIRARILGANHAKSPVLTYLDSHCECTEGWLEPLLDRIARNSTTVVCPVIDVISDETLEYHYRDSGG--VNVGGFDWNLQFSWHPVPERERKRHNSTAEPVYSPTMAGGLFSIDREFFDRLGTYDSGFDIWGGENLELSFKTWMCGGTLEIVPCSHVGHIFRKRSPYKWRSGVNVLKKNSVRLAEVWMDEYSQYYYHR-----IGNDKGDWGDVSDRRKLRNDLKCKSFKWYLDNIYPELFIPGDS-VAHGEIRNLGYGGRTCLDAPAGKKHQKKAVGTYPCHRQGGNQYWMLSKAGEIRR---DDSCLDYAGKDVTLFGCHGGKGNQFWTYR---ENTKQLHHGTSGKCLAISESKDKLLMEECSASLSRQQWTLENYDSSKL", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* :: **: . : ::. .: ::: : :. . * . * : . .. .. : : * :: * *.: : .: . : : * . : : . : *.: : ** **..: .: : .: ::*:.*:.** :.** **::*:* **.* . * *: *..*.*:* ******:.*****:***. :* *: :****** * ***.:** *. *:::* .:*:*** **:***. *:: ***:**:**** .******* ***.:.*.**.* * .*. :*::: * . *.***.* *.*. :* :*::*::. : *: ***:*******.: :*:::****. ::******:*:**:.* *** ***:*** ***:**.:**:.: .*..*: :*.*********.*.: :*:* .: .:**:*:* :**::*:*:.*.***.*:***:*:*. . . * *:*** . ***. ::: *.: * ** *****: :. ::*: .: **. : : * .*: *. . * ::: . *. .::....* * *.. . * * : ", "identical_positions": 216, "similar_positions": 209, "identity": "32.43%" }, { "cls_id": "homologset.agr.MGI:1891654", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I6GBD2-1", "uniprot_id": "A0A8I6GBD2_RAT", "id": "A0A8I6GBD2-1", "name": "Actin-related protein 10", "aln": "MPLYEGLGSGGEKTAVVIDLGEAFTKCGFAGETGPRCIIPSVIKRAGMSKPIKVVQYNINTEELYSYLKEFIHILYFRHLLVNPRDRRVVVIESVLCPSHFRETLTRVLFKYFEVPSVLLAPSHLMALLTLGINSAMVLDCGYRESLVLPIYEGIPVLNCWGALPLGGKALHKELETQLLEQCTVDTGAAKGQSLPSVMGSVPESVLEDIKVRTCFVSDLQRGLQIQAAKFNIDGNNERPSPPPNVDYPL-DGEKILHVLGSIRDSVVEILFEQDNEEKSVATLILDSLLQCPVDTRKQLAENLVIIGGTSMLPGFLHRLLAEIRYLVEKPKY--KKTLGTKNFRIHTPPAKANCVAWLGGAVFGALQDILGSRSISKEYYNQTGRTPDWCSLNNPPLEMMFDVGKTQPPLMKRAFSTEK", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9QZB7-1", "uniprot_id": "ARP10_MOUSE", "id": "Q9QZB7-1", "name": "Actin-related protein 10", "aln": "MPLYEGLGSGGEKTAVVIDLGEAFTKCGFAGETGPRCIIPSVIKRAGMSKPIKVVQYNINTEELYSYLKEFIHILYFRHLLVNPRDRRVVVIESVLCPSHFRETLTRVLFKYFEVPSVLLAPSHLMALLTLGINSAMVLDCGYRESLVLPIYEGIPILNCWGALPLGGKALHKELETQLLEQCTVDTGAAKGQSLPSVMGSVPEGVLEDIKVRTCFVSDLKRGLQIQAAKFNIDGNNERPTPPPNVDYPL-DGEKILHVLGSIRDSVVEILFEQDNEEKSVATLILDSLLQCPIDTRKQLAENLVIIGGTSMLPGFLHRLLAEIRYLVEKPKY--KKTLGTKNFRIHTPPAKANCVAWLGGAVFGALQDILGSRSISKEYYNQTGRIPDWCSLNNPPLEMMFDVGKAQPPLMKRAFSTEK", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9NZ32-1", "uniprot_id": "ARP10_HUMAN", "id": "Q9NZ32-1", "name": "Actin-related protein 10", "aln": "MPLYEGLGSGGEKTAVVIDLGEAFTKCGFAGETGPRCIIPSVIKRAGMPKPVRVVQYNINTEELYSYLKEFIHILYFRHLLVNPRDRRVVIIESVLCPSHFRETLTRVLFKYFEVPSVLLAPSHLMALLTLGINSAMVLDCGYRESLVLPIYEGIPVLNCWGALPLGGKALHKELETQLLEQCTVDTSVAKEQSLPSVMGSVPEGVLEDIKARTCFVSDLKRGLKIQAAKFNIDGNNERPSPPPNVDYPL-DGEKILHILGSIRDSVVEILFEQDNEEQSVATLILDSLIQCPIDTRKQLAENLVVIGGTSMLPGFLHRLLAEIRYLVEKPKY--KKALGTKTFRIHTPPAKANCVAWLGGAIFGALQDILGSRSVSKEYYNQTGRIPDWCSLNNPPLEMMFDVGKTQPPLMKRAFSTEK", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VWE8-1", "uniprot_id": "Q9VWE8_DROME", "id": "Q9VWE8-1", "name": "", "aln": "MPIYESVMQ--EKPPIVLDIGTAYTKLGFAAEAYPRKIMPTEVVMTTTGIRKRLFDYDT-PEELYDQLVDFLQTIFFKHLLVSPKERKFVLVENVFGSTVLRETLARVLFVHFDVSSVLFVPVHLIALSTLAVPTALVVDVGYSETSVMPVFSGVQIMAAFKDQSYGGSAIHAEIKRQLVESGVKES-------------LLTESVLEDIKVRTCFVTTMER------AKARANGDENQPTPAPDVDYIVSDNDAVIQVPGLLRESAYEIMFEASNERDSLPHLILRSILDCTLDVRRALVESVFLVGGGSMVQGLLARLRQELQHLLTEDPFYAERFHGELQFKFFNAVGKQNFTAWLGGALCGAT-DLIQTRSLVKETYLKSEHVPDWSNLCD-----------------NRPTGS--", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "**:**.: . **..:*:*:* *:** ***.*: ** *:*: : : ::.:*: .****. * :*:: ::*:****.*::*:.*::*.*: .: :****:**** :*:*.***:.* **:** **.: :*:*:* ** *: *:*::.*: :: .: . **.*:* *:: **:*. . :: :.*.******.*****: ::* ** . :*::::*:*.*:*** : *.: :::: * :*:*. **:** .**..*:. *** *:::*.:*.*: *.*.:.::** **: *:* ** *:::*: : : :: * *::... .* * .******: ** *:: :**: ** * :: : ***..* : :*. .: ", "identical_positions": 149, "similar_positions": 150, "identity": "35.48%" }, { "cls_id": "homologset.agr.MGI:1891679", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZSM9-1", "uniprot_id": "D3ZSM9_RAT", "id": "D3ZSM9-1", "name": "Integrator complex assembly factor BRAT1", "aln": "--MDAECSRLLPALCAVLADPRQLVADDTCLEKLLDWFKTVTEAEPSLQLLQDHPCLMELLSHVLKPQDVSPRVLSFALRLVGVFAAQEDCFQYLQQGELLLGLFGETGALSWAAWSIPSVRSGWIQGLCSLAHHPSALHFLADSGAVDTIFSLQG-DPSLFVASAASQLLVHILALSMQGGAPG-------SPVPEAV--AWPVCAQKIMNHVEESLHSKATPQVTQALNVLTTTFGR---------------CHNPWTGVLWERLSPPVARLFERDPIP--ATHSLMDLLLSVARSP---------------------VLNFAACGLWEMLAQTLSRLSPTQAGPLALGTLKLQHCPQELRTQAFRVLLQPLACILKATTQAPGPPGLLDGTAGSLLTVDALLSSKSA----------------CVGLLCQTLAHLEELQMLPQCPSPWPQVPLLQAAVTILRLSDGSADPSSSAGGRLCGALGGCVRVQRAALDFLGTLSLGTSP-------LELVLEVFAVLLKTLESPESSPMVLKKAFQATLRWLQSPHKTPSGSDLSPDALLFLG----------------ELFPILQKRLCSPCWEVRDSALEFLTHLIRDWGGQA-DFREALHSSEVPTLARQLLQ-DPESYVRASAVGAAGQLSSQGLQATPAN------QQGLLMDLMHILSTDSEGFPRRAVLRVFTEWLRDGHADVVRDTEWFVATVLQAVSRDLDWEVRVQGLELAQVFLIQAMGQP------------RLHCPYTVGLPGATSSRPHLEFLQTLCRLPLFEFAFCAL--------------------------------LDCDRPVAQKACDLLLFLR---------DKTVSCSNPQEAGDSPNSASVEAALQRWREGEQAQPLGDLEPE--------------AMLAILRSLDLEGLQGRLAKSSDHVEKSP--QSLLQDMLATVGVLEENEA-DCY", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8C3R1-1", "uniprot_id": "BRAT1_MOUSE", "id": "Q8C3R1-1", "name": "Integrator complex assembly factor BRAT1", "aln": "--MDPECSRLLPALCAVLADPRQLVADDTCLEKLLDWFKTVTEAESSLQLLQDHPCLMELLSHVLKPQDVSPRVLSFALRLVGVFAAQEDCFEYLQQGELLLGLFGESGAPGWAAWSIPSVRSGWIQGLCYLAHHPSALHFLADSGAVDTLFSLQG-DPSLFVASAASQLLVHILALSMQGGAPG-------SPVPEAA--AWPMCAQKIVNHVDESLHAKATPQVTQALNVLTTTFGR---------------CHNPWTGVLWERLSPPVARLFERDPIP--AVHALMDLLLSVARSP---------------------VLNFAACGLWEMLAQTLSRLSPIQAGPLALGTLKLQHCPQELRTQAFGVLLQPLACILKATTQAPGPPGLLDGTVGSLLTVDILLASKSA----------------CVGLLCQTLAHLEELQMLPQCPSPWPQVHLLQAALTILHLCDGSADPSSSAGGRLCGTLGGCVRVQRAALDFLGTLSQGTSP-------LELVLEVFAVLLKTLESPESSPMVLKKAFQATLRWLQNPHKTPSSSDLSSDALLFLG----------------ELFPILQKRLCSPCWEVRDSALEFLTHLIRHWGGQA-DFREALRSSEVPTLALQLLQ-DPESYVRASAVGAAGQLSSQGLQAAPASPENSQAQQGLLMDLMHILSTDSEGFPRRAVLRVFTDWLRDGHADVVRDTEWFVATVLQAVSRDLDWEVRVQGLELARVFLTQALGQP------------SLHCPYTVGLPRASSPRPHPEFLQTLCRLPLFEFAFCAL--------------------------------LDCDRPVAQKACDLLLFLR---------DKTVPCSSPREAGDSPNSASVEAALQRWREGEQAQPLGDLDPE--------------AMLAILRALDLEGLQGRLAKSSDHVEKSP--QSLLQDMLATVGVLEENEA-DCY", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6PJG6-1", "uniprot_id": "BRAT1_HUMAN", "id": "Q6PJG6-1", "name": "Integrator complex assembly factor BRAT1", "aln": "--MDPECAQLLPALCAVLVDPRQPVADDTCLEKLLDWFKTVTEGESSVVLLQEHPCLVELLSHVLKVQDLSSGVLSFSLRLAGTFAAQENCFQYLQQGELLPGLFGEPGPLGRATWAVPTVRSGWIQGLRSLAQHPSALRFLADHGAVDTIFSLQG-DSSLFVASAASQLLVHVLALSMRGGAEG-------QPCLPGG--DWPACAQKIMDHVEESLCSAATPKVTQALNVLTTTFGR---------------CQSPWTEALWVRLSPRVACLLERDPIP--AAHSFVDLLLCVARSP---------------------VFSSSDGSLWETVARALSCLGPTHMGPLALGILKLEHCPQALRTQAFQVLLQPLACVLKATVQAPGPPGLLDGTADDATTVDTLLASKSS----------------CAGLLCRTLAHLEELQPLPQRPSPWPQASLLGATVTVLRLCDGSAAPASSVGGHLCGTLAGCVRVQRAALDFLGTLSQGTGP-------QELVTQALAVLLECLESPGSSPTVLKKAFQATLRWLLSSPKTPGCSDLGPLIPQFLR----------------ELFPVLQKRLCHPCWEVRDSALEFLTQLSRHWGGQA-DFRCALLASEVPQLALQLLQ-DPESYVRASAVTAMGQLSSQGLHA-PTSPEHAEARQSLFLELLHILSVDSEGFPRRAVMQVFTEWLRDGHADAAQDTEQFVATVLQAASRDLDWEVRAQGLELALVFLGQTLGPP------------RTHCPYAVALPEVAPAQPLTEALRALCHVGLFDFAFCAL--------------------------------FDCDRPVAQKSCDLLLFLR---------DKIASYSSLREARGSPNTASAEATLPRWRAGEQAQPPGDQEPE--------------AVLAMLRSLDLEGLRSTLAESSDHVEKSP--QSLLQDMLATGGFLQGDEA-DCY", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q1RLU1-1", "uniprot_id": "BRAT1_DANRE", "id": "Q1RLU1-1", "name": "Integrator complex assembly factor BRAT1", "aln": "--MDGDCSSLLPAVCLVLADPKQTPPDDTSLEKLLDWFKDLHSQSNGQVLLEHQPCLLEFISSVCASKATDPAILSFTLKLTGLLAASKQDFHLLEEGGHLVCVFEREAWSVCDLWEDASVRSGWIQGLLNMLKHQQALDFICRQGLIKVILQLQN-DRSLFVACLANQLLVQILKLLTPSDVTSGSDAVVSSKSSSSL--DWVSVSSEITNAVVEALSSENHPQVLQGVQLLSLVLSQ---------------CEEPIRSSLWKDVLPPLEVLINRGSEP--LTQPLMTVLRAAVMTP---------------------LLGQSEYKVEEFLEVMLGTGNRKEGILCATLIVKLEKCPKVLKRKAMDIILLPLQCVSTQSQDEK----------EVDLVLKEPLSQKAL----------------CISLLVQSLSSLAELAHKEYFEG-VCIPSVTSRVVQLLRVCSGHCT-SSLLHVSACTHLIGSCKIQRCGLDTLGALSVYEDN-------LDLRKDIFGVLLDYLKSPDSHATVLKKTFQAVLRWIGVCASFP-------DLLQFISN---------------DLFPVLEKRMCDVRWEVRDSTLEFITQLTVALSDNS-GFVEVLYTSGLVSILLSLLS-DTEGYVRASAVTAVGEAVTSSVQQMALVSKIN-LLEEALAQMMIILSQDTEGFPRRAVVKTFTSWLKGSNPITALDSS--LSSVLSLGGNDFDWEVKMHTLELAEALMEKMLT----------------CCPYAVQSFSSSERTRLTQSLSKLKDLGLFDVLLNGL--------------------------------FDCDRPVCEKSCQLLLKLKRLNAEKADFDHDALVLKACGNRWGDEVQSRFLNKQQVKASEHVLIGGGEGTEK-----DLHCIKEIPLSVILQILDLDDMQRMLKLSSDHVVNSP--RSLMEDILSAAQQSEENIV-DCY", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VDE8-1", "uniprot_id": "BRAT1_DROME", "id": "Q9VDE8-1", "name": "Integrator complex assembly factor Brat1", "aln": "MQKQEETLSRLRTIFDIFLRENFSTTNNVYFEKLLTHLQAKENAFVLQAPFVVEWVDRCITAVTEDFKKIHPKVISFMLNLTSFLANNEWMIVRLRELDIVN---RAVKLLQREHNLSPSIKLGGIRLMKAITVYSMGLAFLRMHRIWTLLIQYSNNDHTLYVVREARQVLYNMVYKSCDKLHDKAVTLEILSEIMQPIHDNLYKNTDGVERIHVKVDDNEMLHKISSTLDLLSYILQQTLVLEERTTLIILLKEHHDFEITVWKLIDMTHNPYFTEKIFTTLSSYNFALLLHEKLLNPNATEPSEEFTEFGLAFFNLMKFLITRKDGLSFVKLAELNHVLWKKLGPRAPKEIVIQQERVTFENQLICFHMLPLLFSMKYAQKIADEESKIELFDAYVVKLLEISCEQTLRLCYTMRDNFFSADGMAVGLVTAGLANKCIHSLLALENVLDREQAVTVCQALLYVLREAVAMSVITNNGEDDCHSVSSAGSSYLKLYPRGTEQVVNDPQVLHSVMVGLRTLIERFKITWKESVETIGLVNCLAFVLENTSMDARCTVQALKLVQLAVEHFLSPNMALLVDNLQGSALVCLGPIIVKRMHDTMWEVRDTTLELTTSIASISRIKFPAFQRFLIDSKIPPIVYEMAKNDSEVYVRASAFQCLSQMVSINLLWENGLS-----QLDLVDHLLFVMYRETNDIVRSEAVITLMKIYEHRKIHEKYKNTLFSTLNYCVIG-DHHTEVKLNALNFWRREFYRQFSNQGMIDGSFPTVTFSKEQKKIVTLTEKEIQTSIAKVFGEVQQYGYFGILLKCLREETSMEVLEFLIKGVKTMTEKFERYKGIMEEIEMRSPLSDRERPRFDFPSQPQPTPIPQQPPVNPTEADEVIESILNSQDAQLLEKAFETQMQINAQGKTAEKRHIDEFYYKQFAVPLRQFFEELKTIDLDQLVKQHQEWFECKENFTSLLDDILGALKRDDENMISDCY", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : * :: :: . .::. :**** :: . : . : : . : . ::** *.*.. :* .: : *.: : .::: * *: : : : .* *: ::. .. * :*:*. * *:* ::: . :. : : :: . :::*: : : . :* : : . . : :* .* .: : *. . * : ::: :. : : . : ** . : . : ..:: . .*: *: : : : .. . .. . * *: . . * . : :* : * :* : . *: * *:: **: *****::**: * : : * * * : : .: . *.* ******. . .: : .: . .:: :: :::.: * .: .: . . : .. : . * . **: : *:: : : : * : : : * . : * :: *:.:: : : . . . . : : . .* .: ::. *. .: : .: . . **::*:*.: : : ***", "identical_positions": 79, "similar_positions": 218, "identity": "8.04%" }, { "cls_id": "homologset.agr.MGI:1891689", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I6A5Z1-1", "uniprot_id": "A0A8I6A5Z1_RAT", "id": "A0A8I6A5Z1-1", "name": "Dynactin subunit 5", "aln": "MELGELLYNKSEYIETASGNKVSRQSVLCGSQNIVLNGKTIIMNDCIIRGDLANVRVGRHCVVKSRSVIRPPFKKFSKGVAFFPLHIGDHVFIEEDCVVNAAQIGSYVHVGKNCVIGRRCVLKDCCKILDNTVLPPETVVPPFTVFSGCPGLFSGE-----LPECTQELMIDVTKSYYQKFLPLTQV--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9QZB9-1", "uniprot_id": "DCTN5_MOUSE", "id": "Q9QZB9-1", "name": "Dynactin subunit 5", "aln": "MELGELLYNKSEYIETASGNKVSRQSVLCGSQNIVLNGKTIIMNDCIIRGDLANVRVGRHCVVKSRSVIRPPFKKFSKGVAFFPLHIGDHVFIEEDCVVNAAQIGSYVHVGKNCVIGRRCVLKDCCKILDNTVLPPETVVPPFTVFSGCPGLFSGE-----LPECTQELMIDVTKSYYQKFLPLTQV--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9BTE1-1", "uniprot_id": "DCTN5_HUMAN", "id": "Q9BTE1-1", "name": "Dynactin subunit 5", "aln": "MELGELLYNKSEYIETASGNKVSRQSVLCGSQNIVLNGKTIVMNDCIIRGDLANVRVGRHCVVKSRSVIRPPFKKFSKGVAFFPLHIGDHVFIEEDCVVNAAQIGSYVHVGKNCVIGRRCVLKDCCKILDNTVLPPETVVPPFTVFSGCPGLFSGE-----LPECTQELMIDVTKSYYQKFLPLTQV--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VJQ6-1", "uniprot_id": "Q9VJQ6_DROME", "id": "Q9VJQ6-1", "name": "Dynactin subunit 5", "aln": "MEIPDTYYSKDEYVETASGNKVSRHTVLCGSQNIILNGKVIVQSGAIIRGDLANVRTGRYCVIGKNSVIRPPYKQFSKGIAFFPMHVGEHVFVGEGAVVSAATIGSYVYIGKNAIIGRRCVLKDCCVIEDGAVLPPETTVSSYMRYTARGTIEGGQGNPYFVPAAMQDEMINYTKSFYEHFVRAPAPAS", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "**: : *.*.**:**********::********:****.*: ...**********.**:**: ..******:*:****:****:*:*:***: *..**.** *****::***.:*********** * *.:******.*..: ::. : .*: :* . *: **: ***:*::*: . ", "identical_positions": 106, "similar_positions": 53, "identity": "56.08%" }, { "cls_id": "homologset.agr.MGI:1891690", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q7TP47-1", "uniprot_id": "HNRPQ_RAT", "id": "Q7TP47-1", "name": "Heterogeneous nuclear ribonucleoprotein Q", "aln": "--------------------------------------MATEHVNGNG-----TEEPMDTTSAVIHSENFQTLLDAGLPQKVAEKLDEIYVA---------------------------------------------------------------------------------------------GQRKYGGPPPDSVYSGQQPSVGTEIFVGKIPRDLFEDELVPLFEKAGPIWDLRLMMDPLTGLNRGYAFVTFCTKEAAQEAVKLYNNHEIRSGKHIGVCISVANNRLFVGSIPKSKTKEQILEEFSKVTEGLTDVILYHQPDDKKKNRGFCFLEYEDHKTAAQARRRLMSGKVKVWGNVGTVEWADPIEDPDPEVMAKVKVLFVRNLANTVTEEILEKSFSQFGKLERVKKLKDYAFIHFDERDGAVKAMEEMNGKDLEGENIEIVFAKPP-DQKRKE--------RKAQRQAAKN-----QMYDDYYYYGPPH--------MPPPTRGRGRGG-RGGYGYPPDYYGYEDYYD---------YYG---------YDYHNYR-------GGYEDPYYGYEDFQVGARG----------RGGRG-ARG-AAPS------RGRGAAPPRGRAG-------------YSQRGGPGSARG-------VRGARGGAQQQRGRGVRGARGGRGGNVGGKRKADGYNQPDSKRRQTNNQNWGSQPIAQQPLQGGDHSG---------NYGYKSENEEFYQDTFGQQWK", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q7TMK9-1", "uniprot_id": "HNRPQ_MOUSE", "id": "Q7TMK9-1", "name": "Heterogeneous nuclear ribonucleoprotein Q", "aln": "--------------------------------------MATEHVNGNG-----TEEPMDTTSAVIHSENFQTLLDAGLPQKVAEKLDEIYVAGLVAHSDLDERAIEALKEFNEDGALAVLQQFKDSDLSHVQNKSAFLCGVMKTYRQRE---KQGTKVADSSKGPDEAKIKALLERTGYTLDVTTGQRKYGGPPPDSVYSGQQPSVGTEIFVGKIPRDLFEDELVPLFEKAGPIWDLRLMMDPLTGLNRGYAFVTFCTKEAAQEAVKLYNNHEIRSGKHIGVCISVANNRLFVGSIPKSKTKEQILEEFSKVTEGLTDVILYHQPDDKKKNRGFCFLEYEDHKTAAQARRRLMSGKVKVWGNVGTVEWADPIEDPDPEVMAKVKVLFVRNLANTVTEEILEKSFSQFGKLERVKKLKDYAFIHFDERDGAVKAMEEMNGKDLEGENIEIVFAKPP-DQKRKE--------RKAQRQAAKN-----QMYDDYYYYGPPH--------MPPPTRGRGRGG-RGGYGYPPDYYGYEDYYD---------YYG---------YDYHNYR-------GGYEDPYYGYEDFQVGARG----------RGGRG-ARG-AAPS------RGRGAAPPRGRAG-------------YSQRGGPGSARG-------VRGARGGAQQQRGRGVRGARGGRGGNVGGKRKADGYNQPDTKRRQTNNQNWGSQPIAQQPLQGGDHSG---------NYGYKSENQEFYQDTFGQQWK", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O60506-1", "uniprot_id": "HNRPQ_HUMAN", "id": "O60506-1", "name": "Heterogeneous nuclear ribonucleoprotein Q", "aln": "--------------------------------------MATEHVNGNG-----TEEPMDTTSAVIHSENFQTLLDAGLPQKVAEKLDEIYVAGLVAHSDLDERAIEALKEFNEDGALAVLQQFKDSDLSHVQNKSAFLCGVMKTYRQRE---KQGTKVADSSKGPDEAKIKALLERTGYTLDVTTGQRKYGGPPPDSVYSGQQPSVGTEIFVGKIPRDLFEDELVPLFEKAGPIWDLRLMMDPLTGLNRGYAFVTFCTKEAAQEAVKLYNNHEIRSGKHIGVCISVANNRLFVGSIPKSKTKEQILEEFSKVTEGLTDVILYHQPDDKKKNRGFCFLEYEDHKTAAQARRRLMSGKVKVWGNVGTVEWADPIEDPDPEVMAKVKVLFVRNLANTVTEEILEKAFSQFGKLERVKKLKDYAFIHFDERDGAVKAMEEMNGKDLEGENIEIVFAKPP-DQKRKE--------RKAQRQAAKN-----QMYDDYYYYGPPH--------MPPPTRGRGRGG-RGGYGYPPDYYGYEDYYD---------YYG---------YDYHNYR-------GGYEDPYYGYEDFQVGARG----------RGGRG-ARG-AAPS------RGRGAAPPRGRAG-------------YSQRGGPGSARG-------VRGARGGAQQQRGRGVRGARGGRGGNVGGKRKADGYNQPDSKRRQTNNQNWGSQPIAQQPLQGGDHSG---------NYGYKSENQEFYQDTFGQQWK", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M3B3W4-1", "uniprot_id": "A0A8M3B3W4_DANRE", "id": "A0A8M3B3W4-1", "name": "", "aln": "--------------------------------------MATEHINGNG-----TEDAMDTAAAVTHSDHFNTLLEAGLPQKVAEKLDEIYLAGLVAHSDLDERAIEALKEFNEEGALQVLIQFKESDLSHVQNKSAFLCGVMKTYRQRE---KQGTKVVESTKGPDEAKIKILLERTGYTLDVTTGQRKYGGPPPESVYTGAQPTVGTEIFVGKIPRDLFEDELVPQFEKAGPIWDLRLMMDPLSGLNRGYAFLTFCTKEAAQEAVKLCNNHEIRPGKHIGVCISVANNRLFVGSIPKSKTKEQIVEEFSKVTEGLTDVILYHQPDDKKKNRGFCFLEYEDHKTAAQARRRLMSGKVKVWGNLVTVEWADPIEDPDPEVMAKVKVLFVRNLANSVTEEILEKAFGQFGNLERVKKLKDYAFVHFNDRDGAVKALTEMNGKELEGEHIEIVFAKPP-DQKRKE--------RKAQRQAAKT-----QMYDDYYYYGPPQ--------MPPPARGRGRGASRGGYSYPPDYYGYEDYYD---------YYG---------YDYHNYR-------GGYDDPYFGYDDFQAPARG----------RGGRGSARGGTSPA------RGRGASAPRGRAG-------------FPQRGGAGAGPGA------SRGLRGGA---RGGVLPRGRGGKGLEAG----------PDMSQ-------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A0B4KHI4-1", "uniprot_id": "A0A0B4KHI4_DROME", "id": "A0A0B4KHI4-1", "name": "", "aln": "MLSQMEASKVQKDEGGGEALSRTILKTPSSFRTPSPIPSCSKMAEGNGELLDDINQKADDRGDGERTEDYPKLLEYGLDKKVAGKLDEIYKTGKLAHAELDERALDALKEFPVDGALNVLGQFLESNLEHVSNKSAYLCGVMKTYRQKSRASQQGVAAPATVKGPDEDKIKKILERTGYTLDVTTGQRKYGGPPP--HWEGNVPGNGCEVFCGKIPKDMYEDELIPLFENCGIIWDLRLMMDPMTGTNRGYAFVTFTNREAAVNAVRQLDNHEIKPGKCLKINISVPNLRLFVGNIPKSKGKDEILEEFGKLTAGLYEVIIYSSPDDKKKNRGFCFLEYESHKAASLAKRRLGTGRIKVWGCDIIVDWADPQEEPDEQTMSKVKVLYVRNLTQDVSEDKLKEQFEQYGKVERVKKIKDYAFIHFEDRDSAVEAMRGLNGKEIGASNIEVSLAKPPSDKKKKEEILRARERRMMQMMQARPGIVGFETLSPYRNLSPTHPSIMSLTPMRPGARMPLRTPIPREYDYFYDFFGFSDYRQGGSFGNNVSYYDDMYRWIDGDYNYYDYPNGGGGGSGGGGGSVSGGTVLPLSAGGSQNSPMASGQRSARGSASGPSASPSLMGVGRGHGITVPRGRVVGQRGSISRLGAQTVPQAAGAAAAAGQAAAAVAQRGATGQGAPAATGGFRGVLPTRPSARGTQHVKPLQNLPVVGKRKFDGGHQNPADVKRRYPSGLIGNGGSWGSLPLPQQPLGTNGEQWYMDTFSAWS-", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .:: :*** :: * . :::.: .**: ** :*** ****** : ********** : * * * *:* ****:*::****:* **:.* **********::* ******:** .:*** :**: :****:.** : : ***.* *****.***** *::*:***.*:* ** :**:* .****************.**:*: *:*** :*::**** *:**** *:** :.*:*****:****:: *:*: *:: * *:*::*****:*****:**::**.**:*: :***:: ..:**: :**** *:*:** * * *: : . * .*.: * * :* * *.* *::*:.** : **. *:*::* ** .. * : * * *..** * * ::.. **:* : ****. .* .*..:. * ** * . . : * * : ", "identical_positions": 228, "similar_positions": 124, "identity": "29.84%" }, { "cls_id": "homologset.agr.MGI:1891691", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P56212-1", "uniprot_id": "ARP19_MOUSE", "id": "P56212-1", "name": "cAMP-regulated phosphoprotein 19", "aln": "MS-----AEVPEAASAEEQKEMEDKVTSPEKAEEAKLKARYPHLGQKPGG-SDFLRKRLQKGQKYFDSGDYNMAKAKMKNKQ-LPAAAPDKTEVTGDHIPTPQDLPQRKPS----------------LVA--SKLAG-------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q712U5-1", "uniprot_id": "ARP19_RAT", "id": "Q712U5-1", "name": "cAMP-regulated phosphoprotein 19", "aln": "MS-----AEVPEAASAEEQKEMEDKVTSPEKAEEAKLKARYPHLGQKPGG-SDFLRKRLQKGQKYFDSGDYNMAKAKMKNKQ-LPAAAPDKTEVTGDHIPTPQDLPQRKPS----------------LVA--SKLAG-------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P56211-1", "uniprot_id": "ARP19_HUMAN", "id": "P56211-1", "name": "cAMP-regulated phosphoprotein 19", "aln": "MS-----AEVPEAASAEEQKEMEDKVTSPEKAEEAKLKARYPHLGQKPGG-SDFLRKRLQKGQKYFDSGDYNMAKAKMKNKQ-LPTAAPDKTEVTGDHIPTPQDLPQRKPS----------------LVA--SKLAG-------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VUB8-1", "uniprot_id": "Q9VUB8_DROME", "id": "Q9VUB8-1", "name": "", "aln": "MSSAEENSNSPATTPQDTETTEQANLTDLEKIEEEKLKSKYPSGMRVPGGHSAFLQKRLQKGQKFFDSGDYQMAKQKGGGVK-QVFAN---KVTTGEAIPTPETVPARKTS----------------IIQPCNKFPATS-----------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9P305-1", "uniprot_id": "IGO2_YEAST", "id": "Q9P305-1", "name": "mRNA stability protein IGO2", "aln": "MS--EDLSPTSSRVDLSNPHGFTKEGVDLSKLSPQELKL-YKMYGKLPSK-KDLLRHKMQD-RQYFDSGDYALKKAGVIKSDDVIVNNSSNNLPVTNPSGLRESIIRRRMSSSSGGDS----------ISRQGSISSGPPP----------------------------RSPNK", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P53897-1", "uniprot_id": "IGO1_YEAST", "id": "P53897-1", "name": "mRNA stability protein IGO1", "aln": "MSN-ENLSPNSSNPDLTKLNNGESGTIDTSKFSPNEMKL-YKMYGKLPSK-KDIFKHTMQK-RKYFDSGDYALQKAGIQNND--PINYGKNNLPLTNPSKLREDIIKRRISTCPSTASTAGVVDNATLIQKEGSISSGPPSSNNGTIGGGSTSSTPVGNHSSSSSSLYTESPIR", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "** : . . .* . ::* * : *. . :::: :*. :::****** : * . . : : : *: * : ..:.. ", "identical_positions": 16, "similar_positions": 32, "identity": "9.2%" }, { "cls_id": "homologset.agr.MGI:1891693", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9Z2C9-1", "uniprot_id": "MTMR7_MOUSE", "id": "Q9Z2C9-1", "name": "Phosphatidylinositol-3-phosphate phosphatase MTMR7", "aln": "------------MEHIRTP------------------------------------------------------------KVENVRLVDRVSCKKAALGTLYLTATHVIFVENAPDTRKETWILHSQISTIEKQATTATGCPLLIR------------------------------CKNFQIVQLVIP--QERDCHDVYISLIRLARPVKYEELYCFSFNPK--LDKEEREQGWLLVDLSEEYKRMGLPDN----YWQLSDVNRDYRVCDSYPTELYVPRSATAHIIVGSSKFRSRRRFPALSYYCKDSHASICRSSQPLSGFS-ARCLEDE----QMLQAIRKANPGSDFIYVVDTRPKLNAMANRAAGKGYENEDNY-----------------SNIKFQFIGIENIHVMRNSLQKMLEVCE----LKSPSMSDFLWGLENSGWLRHIKAIMDAGIFIAKAVSEEGASVLVHCSDGWDRTAQVCSVASLLLDPYYRTLKGFMVLIEKDWISFGHKFNHRYGNLDGDPKEISPVIDQFIECVWQLTEQFPCAFEFNERFLTHIQHHVYSCQFGNFLCNSQKERRELKIQERTYSLWSNLWKNRADYLNPLFRADHSQTQGSLHLPTAPCNFTYKFWNGMYNRFEKGLQPRQSVTDYLMAVKEESQQLEEELESLEERLEKIQKVHLHGTKVKSKQSEPSKHSGFSTSDHSTANTPQDYS---GNSKSFPSRSPSQGDEDSALILTQDNLKSSDP--------DLSVNSDQESGVEDLSCRS-----PSGGEHAPSEDSGKDRDSDEAVFLTA----------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8I6AEZ2-1", "uniprot_id": "A0A8I6AEZ2_RAT", "id": "A0A8I6AEZ2-1", "name": "", "aln": "------------MEHIRTP------------------------------------------------------------KVENVRLVDRVSCKKAALGTLYLTATHVIFVENAPDTRKETWILHSQISTIEKQATTATGCPLLIR------------------------------CKNFQIVQLVIP--QERDCHDVYVSLIRLARPVRYEELYCFSFNPK--LDKEEREQGWLLVDLSEEYKRMGLPDN----YWQLSDVNRDYRVCDSYPTELYVPRSATAHIIVGSSKFRSRRRFPALSYYCKESHASICRSSQPLSGFS-ARCLEDE----QMLQAIRKANPRSDFIYVVDTRPKLNAMANRAAGKGYENEDNY-----------------SNIKFQFIGIENIHVMRNSLQKMLEVCE----LKSPSMSDFLWGLENSGWLRHIKAIMDAGIFIAKAVSEEGTSVLVHCSDGWDRTAQVCSVASLLLDPYYRTLKGFMVLIEKDWISFGHKFNHRYGNLDGDPKEISPVIDQFIECVWQLMEQFPCAFEFNERFLIHIQHHVYSCQFGNFLCNSQKERRELKIQERTYSLWSNLWKNRADYLNPLFRADHSQTQGSLHLPTAPYNFTYKFWNGMYNRFEKGLQPRQSVTDYLMAVKEESQQLEEELESLEERLEKIQKVHLNGAKVKSKQSEPSKHSGFSTSDNSTANTPQDYS---GNMKSFPSRSPSQGDEDSALILTQDNLKSSDP--------DLSVNSDQESGVEDLSCRS-----PSGGEHAPSEDSGKDRDSDEAVFLTA----------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9Y216-1", "uniprot_id": "MTMR7_HUMAN", "id": "Q9Y216-1", "name": "Phosphatidylinositol-3-phosphate phosphatase MTMR7", "aln": "------------MEHIRTP------------------------------------------------------------KVENVRLVDRVSPKKAALGTLYLTATHVIFVENSPDPRKETWILHSQISTIEKQATTATGCPLLIR------------------------------CKNFQIIQLIIP--QERDCHDVYISLIRLARPVKYEELYCFSFNPM--LDKEEREQGWVLIDLSEEYTRMGLPNH----YWQLSDVNRDYRVCDSYPTELYVPKSATAHIIVGSSKFRSRRRFPVLSYYYKDNHASICRSSQPLSGFS-ARCLEDE----QMLQAIRKANPGSDFVYVVDTRPKLNAMANRAAGKGYENEDNY-----------------SNIKFQFIGIENIHVMRNSLQKMLEVCE----LKSPSMSDFLWGLENSGWLRHIKAIMDAGIFIAKAVSEEGASVLVHCSDGWDRTAQVCSVASLLLDPHYRTLKGFMVLIEKDWISFGHKFNHRYGNLDGDPKEISPVIDQFIECVWQLMEQFPCAFEFNERFLIHIQHHIYSCQFGNFLCNSQKERRELKIQERTYSLWAHLWKNRADYLNPLFRADHSQTQGTLHLPTTPCNFMYKFWSGMYNRFEKGMQPRQSVTDYLMAVKEETQQLEEELEALEERLEKIQKVQLNCTKVKSKQSEPSKHSGFSTSDNSIANTPQDYS---GNMKSFPSRSPSQGDEDSALILTQDNLKSSDP--------DLSANSDQESGVEDLSCRS-----PSGGEHAPSEDSGKDRDSDEAVFLTA----------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M2BFN3-1", "uniprot_id": "A0A8M2BFN3_DANRE", "id": "A0A8M2BFN3-1", "name": "", "aln": "------------MEHIRTP------------------------------------------------------------KVENVRMIDRRTPRKATVGTLYLSSTHTIFVENS-EARKETWVLHSLVSNVERLPTNPSGSPVIIR------------------------------CKNLIVYRLLIP--QEKDSLDVVASLTRLSRPERYGELFCFSFNPN--LDKELREKAWGFMDLKAEFNRMGIPSN----LWHVTAANHEYRLCDTYPSELFVPKSASPAVIVGSAKFRSRGRLPVLSYFHRDTSASICRSSQPLSGFS-ARSSDDE----QMLQAIMKSNPVSEFMYVVDTRPKLNAMANRAAGKGYENEDHY-----------------TNIKLQFIGIENIHVMRNSQQKLIDVGD----MAAPSMADFLWGLENSGWLKHIKAVLDAGVFIAKAVAEDGVSVLVHCSDGWDRTAQACSVASVLLDPYYRTIKGLMVLIEKDWVSFGHKFSHRYAHLDGDPKEVSPVMDQFLECVWQLMQQFPCAFEFNERFLIQLHMLIYSCQYGNFIGNCQKERRDLKLQERTHSLWPHLWENRAEYTNPLYRTDHSQTQGVLRPLTT--AYCFKFWKGMYGRAERSLSSQQSPADCLNAVREESQQLEEELTAHQERLAQLKEKKTSGERKK--ISRLSESARRPTPNEGELDSPQDYF---STPRGE-KHTPS---FTLPLDLAAQTKNGDPD--------DLSTCSDLESGVADLSSHS-----SSAG------DDNKDPDSEEVVKIPA----------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q8MLR7-1", "uniprot_id": "Q8MLR7_DROME", "id": "Q8MLR7-1", "name": "phosphatidylinositol-3,5-bisphosphate 3-phosphatase", "aln": "MDITRFMNKFNEIERQLSPTSALRLSFDNISPETEEPPDGNKRLWGVPVPPFVSEKVVSWIEEEFNEAPVFYNGNSVLKKVENVRMIDRYNTKNPTVGTLYLTATHLIFVEPD--SNKETWILHMHVASIEKLPLSTTGSPLLIR------------------------------CKTFLSVTFVIP--KDSECHDVYTSLLKLFQPVSINKLYCFNYQPN--KDDFPKNAGWDYFKLEAEFKHMLVPNE----AWTLCSMNEKYELCDTYPRQIYVPKEATTLMLISSSRFRSKGRLPVLTYLHNN-KASICRCSQPLSGFS-ARCLEDE----QMLEAIRKTNSNTDYMYVVDTRPRINAMANRAAGKGYENEAFY-----------------ENIKFHFLGIENIHVQRASLQKVLEACE----QKSPTMSAFINALESSGWLKHIRSILDTSSFIANAVDK-GVSVVVHCSDGWDRTAQVCSLAQLMLNPYYRTIKGFQALIEKDWLAFGHKFSERCGHIQTDAREVSPIFTQFLDCTWQLMSQRSEAFEFNERFLLILHDHVHSCQFGTFVGNCEKDRLDLKLAERTFSLWGYMANHLNEYINPLYKPNVDEAIKANLAPQC-----IKFWRGMYSRFESGIHPREPLGDVLLDSKEHCNSLEDHVQHLTKRIASFKNYISKSAKKLQDATSAPGKVNKELSSNEINDNKYNYDKKLSELSAADDDHPLKASNMSFASLSLSAEQSSPPQALPEEINSVAVDWKPMRNVTTCSCSTPFDQFSKKTHCWRCGDIFCERCIDKNVALPGHDSGKPVPVCRGCFRQMQKQSP", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P47147-1", "uniprot_id": "YMR1_YEAST", "id": "P47147-1", "name": "Phosphoinositide 3-phosphatase", "aln": "------------MEYIKIA------------------------------------------------------------KVSNVVLHRRG---TATQGTLHLTTHHLIFESPQ--LSTEFWFPYPLIYGVHKNPGSTLLSKLTSTNQIQLEGTDSQNYKLYQGKDLWSFVNIKVIGKDYAVFSLDFGGDLHLQARKVYDSILNLTVLSNITQLYAFIYISNNLERKLPSPDSWDIYDPIKEFRRQGLDSKDETCPWRLSTVNEHYEFCPTYPSKLFVPRSTSDILLKHASKFRSQKRIPVLTYHHKATDCNILRSSQPLPGLINQRSIQDEKLVWESFNSFCNKDIRRTKHVIVDARPRTNALAQMALGGGTENMDNYNFFLADNNMGVDKSLKLPTVTRLFLGIDNIHIVSNTAAYMTEVICQGGDLNLPLEQNLIRSQKFSNWLKLNTLILKSVDMLLKSIIFNHSNVLVHCSDGWDRTSQVVSLLEICLDPFYRTFEGFMILVEKDWCSFGHRFLERSGHLNSDIRFHDNTMHSNFNDVDTNGDDLDIGVNTQDDYAEDDEGGEDETNLINLSRISKKFNENFKLNKKSLKFVSPVFQQFLDCVYQLLTQNPDLFEFNERFLRR---LVYHLYSCQYGTFLSNSEKEKFQQNLPNKTKSVWDYFRSRRKQFIN--PNFIQRKRSGMNEHDQNLEEEEKVEWISPDLKKVQWWWQLY---GRKDSEMNDELRHKRDSVPISVDKKSKEHSNS--------DGGKGLNLSIFGFDMFNRK-----------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :* . **.** : * ..: ***:*:: * ** . .* *. : : :.: . .. . : * : : . :. .* *: .* :*:.* : . . .* . *: : : .. * : *..*..* :** :::**:.:: :: :::***: *:*.*:* . ..* *.****.*: *. :** : :::: : : :**:**: **:*: * * * ** * .:. *:**:***: : : :. * :: . : *.**: ::.: :: ::: .*:**********:*. *: .: *:*.***::*: *:**** :***:* .* .::: * : . : . :: . .: ..: :: : . . : .: .:* . ::*: ::: .: : :: : * : . ::: *. . .: : :. : :... : .: : . .. : : . . . : . : . . . . . ", "identical_positions": 105, "similar_positions": 203, "identity": "12.59%" }, { "cls_id": "homologset.agr.MGI:1891694", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q5XIG5-1", "uniprot_id": "GKAP1_RAT", "id": "Q5XIG5-1", "name": "G kinase-anchoring protein 1", "aln": "MASAVLSSVLTTASRFALLQVDSGSGSDSEPGK--GKGRNNGKSQT----LGNKSTANEKKREKRRKKKEQQQSEANELRNLAFKKIPQKS----SHSVCNVQHELSLPNPVQKESR-EENWQEWRQRDEQLTSEMFEADLEKALLLSKLEYEEHRQDYENAENASTQTKVINKKDKRKNHQGKDKPLTVSLKDFQCEDHISKKTEESNSSQPLSHDGGFFNRLEDDVHKILVREKRREQLTEHNGTDNCPAPEHNQEVGLKDGRIERLKLELERKDAEIQKLKAVVTQWEAKYKEVKARNGQLLKMLQEGEMKDKAEILLQVDESQSIKNELTVQVSSLHAALEQERSKVKVLQAELAKYQGGRKGKRNCEPDQCR", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9JMB0-1", "uniprot_id": "GKAP1_MOUSE", "id": "Q9JMB0-1", "name": "G kinase-anchoring protein 1", "aln": "MASAVLSSVLTTASRFALLQVDSGSGSDSEPGK--GKGRSNGKSQT----LGNKATSNEKKREKRRKKKEQQQSEANELRNLAFKKIPQKS----SHSICNVQHELSSPNPAQKESR-EENWQEWRQKDEQLTSEMFEADLEKALLLSKLEYEEHKQDYENAETASTQTKGINKKDKRKNHQGKDKPVTVSLKDFQCEDHISKKAEESNSAQTLSHDGGFFNRLEDDVHKILIREKRREQLTEHNGTDNSPAPEHNQEVGLKDGRIERLKLELERKDAEIQKLKAVITQWEAKYKEVKARNGQLLKMLQEGEMKDKAEILLQVDESQSIKNELTVQVSSLHAALEQERSKVKVLQAELAKYQGGRKGKRNFEPDHCR", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q5VSY0-1", "uniprot_id": "GKAP1_HUMAN", "id": "Q5VSY0-1", "name": "G kinase-anchoring protein 1", "aln": "MASAVLSSVPTTASRFALLQVDSGSGSDSEPGK--GKGRNTGKSQT----LGSKSTTNEKKREKRRKKKEQQQSEANELRNLAFKKIPQKS----SHAVCNAQHDLPLSNPVQKDSR-EENWQEWRQRDEQLTSEMFEADLEKALLLSKLEYEEHKKEYEDAENTSTQSKVMNKKDKRKNHQGKDRPLTVSLKDFHSEDHISKKTEELSSSQTLSHDGGFFNRLEDDVHKILIREKRREQLTEYNGTDNCTAHEHNQEVVLKDGRIERLKLELERKDAEIQKLKNVITQWEAKYKEVKARNAQLLKMLQEGEMKDKAEILLQVDESQSIKNELTIQVTSLHAALEQERSKVKVLQAELAKYQGGRKGKRNSESDQCR", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6NWC9-1", "uniprot_id": "GKAP1_DANRE", "id": "Q6NWC9-1", "name": "G kinase-anchoring protein 1", "aln": "MASAVIS-VPTTASRFALLQVDSDSDSDSDVGKPKAAGRGAGKPRSGKSPSGKNSQNNEKKKEKRRRKKEQQQSEANELRSLAFKKIPQKSTAPPSLTLQDLANDLINPANVQQGSKPQENWQEWKQRDEQLTSDLYEADLEKALMLSKLEFEEHKKDADKAETASPKTKTGGKKDRKKNQQGKDKRVTVSLKDFQQEDQLKNKPEREPVNPALRDDK-FFNKLEDDVSKIVQRDKRREQYSNSAGQEVNTSSEHEQDV-----RTEQLKYELEKKDQEIAKLKKTISQWEERYKEVKARNSQLLKMLQQGEMKDKAEILLQVEELLNIKEELSSQVTQLHTALEQERSKVKGLQSEQPKHQGNRKGKKASEGDV--", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*****:* * *************.*.***: ** . **. **.:: *.:: ****:****:*************.********** * :: : ::* . .*: *: :******:*:******:::********:*****:***::: :.**.:*.::* .***::**:****: :*******: **::.:*.*. .* .* ***:***** **: *:***** :: * : .: **:*:* * *:** ***:** ** *** .::*** :********.*******:*************:* .**:**: **:.**:********** **:* .*:**.****: * * ", "identical_positions": 218, "similar_positions": 87, "identity": "57.82%" }, { "cls_id": "homologset.agr.MGI:1891697", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O08707-1", "uniprot_id": "ACKR2_MOUSE", "id": "O08707-1", "name": "Atypical chemokine receptor 2", "aln": "MPTVASPLPLTTVGSEN-SSSIYDYDYLDDMTILVCRKDEVLSFGRVFLPVVYSLIFVLGLAGNLLLLVVLLHSAP-RRRTMELYLLNLAVSNLLFVVTMPFWAISVAWHWVFGSFLCKVISTLYSINFYCGIFFITCMSLDKYLEIVHAQPLHRPKAQFRNLLLIVMVWITSLAISVPEMVFVQIHQTLDGVWHCYADFGGHATIWKLYLRFQLNLLGFLLPLLAMIFFYSRIGCVLVRLRPPGQGRALRMAAALVIVFFMLWFPYNLTLFLHSLLDLHVFGNCEISHRLDYTLQVTESLAFSHCCFTPVLYAFCSHRFRRYLKAFLSVMLRWHQAPG---TPSSNHSESSRVTAQEDVVSMNDLGERQSEDSLNKGEMGNT--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O09027-1", "uniprot_id": "ACKR2_RAT", "id": "O09027-1", "name": "Atypical chemokine receptor 2", "aln": "MPTIASPLPLATTGPEN-GSSIYDYDYLDDVTVLVCSKDEVLSFGRVFLPVVYSLIFVLGLAGNLLLLVVLLHSVPQRRRMIELYLLNLAVSNLLFVVTMPFWAISVAWHWVFGSFLCKVVSTLYSINFYCGIFFITCMSLDKYLEIVHAQPLHRPKTRFRNLLLIVMVWITALAVSVPEMVFVKVHQTLDGVWHCYADFGGHATIWKLYLRFQMNLLGFLFPLLAMIFFYSRIGCVLVRLRPPGQGRALRMAAALVVVFFLLWFPYNLTLFLHSLLDLHVFGNCKISHRLDYMLQVTESLAFSHCCFTPVLYAFSSHSFRQYLKAVLSVVLRRHQAPGTAHAPPCSHSESSRVTAQEDVVSMNDLGERQADISLNKGEIGNN--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O00590-1", "uniprot_id": "ACKR2_HUMAN", "id": "O00590-1", "name": "Atypical chemokine receptor 2", "aln": "MAATASPQPLATEDADSENSSFYYYDYLDEVAFMLCRKDAVVSFGKVFLPVFYSLIFVLGLSGNLLLLMVLLRYVP-RRRMVEIYLLNLAISNLLFLVTLPFWGISVAWHWVFGSFLCKMVSTLYTINFYSGIFFISCMSLDKYLEIVHAQPYHRLRTRAKSLLLATIVWAVSLAVSIPDMVFVQTHENPKGVWNCHADFGGHGTIWKLFLRFQQNLLGFLLPLLAMIFFYSRIGCVLVRLRPAGQGRALKIAAALVVAFFVLWFPYNLTLFLHTLLDLQVFGNCEVSQHLDYALQVTESIAFLHCCFSPILYAFSSHRFRQYLKAFLAAVLGWHLAPGTAQASLSSCSESSILTAQEEMTGMNDLGERQSENYPNKEDVGNKSA", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*.: *** **:* ..:. .**:* *****:::.::* ** *:***:*****.*********:******:***: .* *** :*:******:*****:**:***.***************::****:****.*****:*************** ** ::: :.*** .:** .:**:*:*:****: *:. .***:*:******.*****:**** ******:*********************.******::*****:.**:************:****:*****::*::*** ******:** ****:*:****.** **:****.*:.:* * *** :. .. **** :****::..********:: ** ::**. ", "identical_positions": 260, "similar_positions": 89, "identity": "67.53%" }, { "cls_id": "homologset.agr.MGI:1891698", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A0G2JUH4-1", "uniprot_id": "A0A0G2JUH4_RAT", "id": "A0A0G2JUH4-1", "name": "Bifunctional polynucleotide phosphatase/kinase", "aln": "------------MSELGSRGRLWLQSPTGGPPPIFLPSDGQALVLGRGPLTQVMDRKCSRNQVELIADPETRTVAVKQLGVNPSTVGVQELKPGVSGSLSVGDVLYLVNGLYPLTLRWEEIS-------------------------------------------------TPGSPPDTPPGNP-VDPEEGKDTE----------------PQKKRMRKSSPG-------WESFKQLLVFTASGVKPRGKVAAFDLDGTLITTRS-GKVFPTSPSDWRILYPEIPKKLQELAAEGYKLVILTNQMGIGRGKLPAEVFKAKVEAVLEKLGVPFQVLVATHAGLNRKPVSGMWDHLQEKGNEGIPISIGDSVFVGGSR-APSQLG-PREEEKGFLLCRPPGKPGFALNVGLPFATPEEFFLKWPAARFELPAFDPRTISSAGPLYLPESSFLLSPNPEVVVAVGFPGAGKSTFIQKHLVSAGYVHVNRDTLGSWQRCVNSCQAALRQGKQVVIDNTNPDIQSRARYIQCAKDAGVPCRCFSFCATIEQARHNNRFREMTDPS--HAPVSDMVMFSYRKQFEPPTLAEGFLEILQVPFRLQEHLDPALQRLYCQFSEG-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9JLV6-1", "uniprot_id": "PNKP_MOUSE", "id": "Q9JLV6-1", "name": "Bifunctional polynucleotide phosphatase/kinase", "aln": "------------MSQLGSRGRLWLQSPTGGPPPIFLPSDGQALVLGRGPLTQVTDRKCSRNQVELIADPESRTVAVKQLGVNPSTVGVHELKPGLSGSLSLGDVLYLVNGLYPLTLRWEELS-------------------------------------------------TSGSQPDAPPDTP-GDPEEGEDTE----------------PQKKRVRKSSLG-------WESLKKLLVFTASGVKPQGKVAAFDLDGTLITTRS-GKVFPTSPSDWRILYPEIPKKLQELAAEGYKLVIFTNQMGIGRGKLPAEVFKGKVEAVLEKLGVPFQVLVATHAGLNRKPVSGMWDHLQEQANEGIPISVEDSVFVGDAAGRLANWA-PGRKKKDFSCADR----LFALNVGLPFATPEEFFLKWPAARFELPAFDPRTISSAGPLYLPESSSLLSPNPEVVVAVGFPGAGKSTFIQEHLVSAGYVHVNRDTLGSWQRCVSSCQAALRQGKRVVIDNTNPDVPSRARYIQCAKDAGVPCRCFNFCATIEQARHNNRFREMTDPS--HAPVSDMVMFSYRKQFEPPTLAEGFLEILEIPFRLQEHLDPALQRLYRQFSEG-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q96T60-1", "uniprot_id": "PNKP_HUMAN", "id": "Q96T60-1", "name": "Bifunctional polynucleotide phosphatase/kinase", "aln": "------------MGEVEAPGRLWLESPPGGAPPIFLPSDGQALVLGRGPLTQVTDRKCSRTQVELVADPETRTVAVKQLGVNPSTTGTQELKPGLEGSLGVGDTLYLVNGLHPLTLRWEETR-------------------------------------------------TPESQPDTPPGTPLVSQDEKRDAE----------------LPKKRMRKSNPG-------WENLEKLLVFTAAGVKPQGKVAGFDLDGTLITTRS-GKVFPTGPSDWRILYPEIPRKLRELEAEGYKLVIFTNQMSIGRGKLPAEEFKAKVEAVVEKLGVPFQVLVATHAGLYRKPVTGMWDHLQEQANDGTPISIGDSIFVGDAAGRPANWA-PGRKKKDFSCADR----LFALNLGLPFATPEEFFLKWPAAGFELPAFDPRTVSRSGPLCLPESRALLSASPEVVVAVGFPGAGKSTFLKKHLVSAGYVHVNRDTLGSWQRCVTTCETALKQGKRVAIDNTNPDAASRARYVQCARAAGVPCRCFLFTATLEQARHNNRFREMTDSS--HIPVSDMVMYGYRKQFEAPTLAEGFSAILEIPFRL--WVEPRLGRLYCQFSEG-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A0R4IRS4-1", "uniprot_id": "A0A0R4IRS4_DANRE", "id": "A0A0R4IRS4-1", "name": "Bifunctional polynucleotide phosphatase/kinase", "aln": "-------------MEMQCT----LVSVDGDR--VVLP-DGRALMFGRGPESRISDKKCSRHQVKLVADYAKQEVLVTQLGPNPSSLDGQCLGRGESGCLTTGQTLYLVNESYPFTVEFAFHCGIQLSSSPQKKEKITNESKQRQKSSKESSGSLKRNIHDYFSKSPKKAAKRPYSPEDDVPQPKRGREDEDNEDEGTSAEQKLQQLQAFAQSESDNFKSSNPSSTCSQSHWQQIGSLMLFTAAGVTASSKIAGFDIDGCIITTKS-GKVFPTGPDDWRILYPEIQPKLASLLKKGYKVVFFTNQMGISRGKLRPEVFKSKAEDILQTLQLPIQVFVSTAPGIYRKPVIGMWEHLCEKANSGVMVDVSESFYVGDAAGRPANWA-PGKKKKDFSCSDR----LFALNIGLQFYTPEEYFLGWKPATFSFPEFDPRKLDSKARLYDPPDASLTSTKQEIIVAVGFPGAGKSTFFQTHIIPKGYAYVNRDTMGSWQHCVSACERALKEGKSVAVDNTNPDLESRKRYIDVAQSAGVSCRCFNFTASLDQAKHNNRFREMVPSATKHVPVNDMVIHSYKKKFVVPSLSEGFSEVLQIHFVP-SFSDKRSEFLFKQFSEG-", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VHS0-1", "uniprot_id": "Q9VHS0_DROME", "id": "Q9VHS0-1", "name": "", "aln": "MSMAKYLNRSVGKAGKDVAARICTLKPTEPEHHSIHLTAGEN-FVGRSRETGIRDSKCSKRQIQLQVDLKKAVVSLKVLGVNPCGVNGLMLMQNGERELKHGDLVEIVYGRHQFEVVFNPPP--------------------------------------------------EYDKEKAEPLSTTLSPSE----------------------KSERWDSSGNG------------KLVIFTSVGVKGSEKIAGYDMDGTIIKTKS-GLVFPKNTDDWQIIFPEVPEKLKNLHKDGFKICLFTNQGGIARGKINLDDFKVKIKHIVAKLGVPIQVFIAIGDGFYRKPLTGMWQHLKSEMNDGVEIQEDRCFFVGDAAGRPETGKGATKRRKDHSLVDR----LFAANVGISFYTPEVHFLGKQVEQWNKPDFEPTSVQDQVSLLDPDDLTLDDHPCEMVIMVGLPGSGKSHFCSSFFQPRGYKIVNADTLGSTQNCLTACKRFLDSGQSCVVDNTNVDAASRKKFLQLASEKMIPCRCLVMNVPVAQVKHNIAFRELSDSAR--TKIKDMVFNMMKKKYQEPALDEGFISIHKVNFKP-NFADEKQEKLYKMYLVEK", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q03796-1", "uniprot_id": "TPP1_YEAST", "id": "Q03796-1", "name": "Polynucleotide 3'-phosphatase", "aln": "----------------------------------------------------------------------------------------------MSHKLTILPFLIKFTPKFPQSIDHDEHG------------------------------------------------------------------------------------------------------------------------------LNVYAFDLDHTIIKPKSPNISFSRSASDWQFINFNSKKSTLDYLCN-----IIDND-------------PTAVIVIFSNQGGVITVPRTSKS--CTKYTNKILLFLKAIKNDERGETLSHRLWLYAAPKRPKTFA--------------------ANHSKITFASLGESYN---------------------------------NDPNIFEKVRKPMTGMVEFFKRDLES--AYRVSEQISPIKLNWIYYCG----------------DAAGRK-------------------------------KDFSDSD------------------------IKFAENLHVEFKY-------PEEIFHG-----", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . * : . . : :: .:*:* :*..:* . *. ...**::: : . . . :: *: :. . : * : * : .* *. .:: : * : : * : : ::. * * :* * . : . *. : . : * * .* ::: . * .: * :: ", "identical_positions": 25, "similar_positions": 65, "identity": "4.06%" }, { "cls_id": "homologset.agr.MGI:1891699", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9Z2W1-1", "uniprot_id": "STK25_MOUSE", "id": "Q9Z2W1-1", "name": "Serine/threonine-protein kinase 25", "aln": "MAHLRGFAHQ---HSRVDPEELFTKLDRIGKGSFGEVYKGIDNHTKEVVAIKIIDLEEAEDEIEDIQQEITVLSQCDSP-YITRYFGSYLKSTKLWIIMEYLGGGSALDLLKPGPLEETYIATILREILKGLDYLHSERKIHRDIKAANVLLSEQGDVKLADFGVAGQLTDTQIKRNTFVGTPFWMAPEVIKQ-SAYDFKADIWSLGITAIELAKGEPPNSDLHPMRVLFLIPKNNPPTLEG-HHSKPFKEFVEACLNKDPRFRPTAKELLKHKFITRY-TKKTSFLTELIDRYKRWK----------------------------SEGHGEESSS----------------------------------EDSDIDGEAEDGEQ------------------------------------------------GPIWTFPPTIRPSP---------------------------------------------------------------HSKLHKGT------ALHSSQK--------------------------------------------------------------------------PAEPIKRQPR----------------------------------------------------------------------------------------------------------------------------------------SQCLSTLVRP--------------------------------------------VFGELKEKHKQSGGS-----------------VG-ALEELENAFSLAEESCPGISDKLMVHLVERVQR-FSHSRNHLTSTR---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6V9V9-1", "uniprot_id": "Q6V9V9_RAT", "id": "Q6V9V9-1", "name": "Serine/threonine-protein kinase 25", "aln": "MAHLRGFAHQ---HSRVDPEELFTKLDRIGKGSFGEVYKGIDNHTKEVVAIKIIDLEEAEDEIEDIQQEITVLSQCDSP-YITRYFGSYLKSTKLWIIMEYLGGGSALDLLKPGPLEETYIATILREILKGLDYLHSERKIHRDIKAANVLLSEQGDVKLADFGVAGQLTDTQIKRNTFVGTPFWMAPEVIKQ-SAYDFKADIWSLGITAIELAKGEPPNSDLHPMRVLFLIPKNNPPTLEG-HHSKPFKEFVEACLNKDPRFRPTAKELLKHKFITRY-TKKTSFLTELIDRYKRWK----------------------------SEGHGEESSS----------------------------------EDSDIDGEAEDGEQ------------------------------------------------GPIWTFPPTIRPSP---------------------------------------------------------------HSKLHKGT------ALHSSQK--------------------------------------------------------------------------PAEPIKRQPR----------------------------------------------------------------------------------------------------------------------------------------SQCLSTLVRP--------------------------------------------VFGELKEKHKQSGGS-----------------VG-ALEELENAFSLAEESCPGISDKLMVHLVERVQR-FSHSRNHLTSTR---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O00506-1", "uniprot_id": "STK25_HUMAN", "id": "O00506-1", "name": "Serine/threonine-protein kinase 25", "aln": "MAHLRGFANQ---HSRVDPEELFTKLDRIGKGSFGEVYKGIDNHTKEVVAIKIIDLEEAEDEIEDIQQEITVLSQCDSP-YITRYFGSYLKSTKLWIIMEYLGGGSALDLLKPGPLEETYIATILREILKGLDYLHSERKIHRDIKAANVLLSEQGDVKLADFGVAGQLTDTQIKRNTFVGTPFWMAPEVIKQ-SAYDFKADIWSLGITAIELAKGEPPNSDLHPMRVLFLIPKNSPPTLEG-QHSKPFKEFVEACLNKDPRFRPTAKELLKHKFITRY-TKKTSFLTELIDRYKRWK----------------------------SEGHGEESSS----------------------------------EDSDIDGEAEDGEQ------------------------------------------------GPIWTFPPTIRPSP---------------------------------------------------------------HSKLHKGT------ALHSSQK--------------------------------------------------------------------------PAEPVKRQPR----------------------------------------------------------------------------------------------------------------------------------------SQCLSTLVRP--------------------------------------------VFGELKEKHKQSGGS-----------------VG-ALEELENAFSLAEESCPGISDKLMVHLVERVQR-FSHNRNHLTSTR---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M2BDG3-1", "uniprot_id": "A0A8M2BDG3_DANRE", "id": "A0A8M2BDG3-1", "name": "non-specific serine/threonine protein kinase", "aln": "MAHLQNIRNQ---NSRLNPEEYFTKLERIGKGSFGEVYKGINNRTKEVVAIKIIDLEEAEDEIEDIQQEITVLSQCDSP-YVTKYYGSYLTGSKLWIIMEYLGGGSALDLLRPGTLEEVYIATILREILKGLDYLHSERKIHRDIKAANVLLSEHGEVKLADFGVAGQLTDTQIKRNTFVGTPFWMAPEVIKQ-SAYDFKADIWSLGITAIELAKGEPPNAELHPMRVLFLIPKNNPPTLEG-SYSKAFKDFVEACLNKEPRFRPTAKELLKHKFITRY-TKKTSYLSELIDRYRRWK----------------------------SEGHGEESSS----------------------------------DDSDMDGEGDDRDQ------------------------------------------------GPMWTFP-TVRPST---------------------------------------------------------------INKLNRG-------LSHLDNK--------------------------------------------------------------------------TSDVMKRQPK----------------------------------------------------------------------------------------------------------------------------------------SSSLTSFITP--------------------------------------------IFKELKEKRRVGGNG-----------------VC-AVEELENAFSLAEESSPGISDRLLNHVMERVCR-FTLNGNSLPLKR---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VEN3-1", "uniprot_id": "Q9VEN3_DROME", "id": "Q9VEN3-1", "name": "non-specific serine/threonine protein kinase", "aln": "-------MSW---TEKVDPELIFTKQERIGKGSFGEVFKGIDNRTQQVVAIKIIDLEEAEDEIDDIQQEIMVLSQCDSP-YVTKYYGSFLKGTKLWIIMEYLGGGSALDLMKAGSFEEMHIGIILREVLKGLDYLHSERKLHRDIKAANVLLSEQGDVKLADFGVAGQLTNTTSKRNTFVGTPFWMAPEVIKQ-SQYDAKADIWSLGITAIELAKGEPPNSELHPMRVLFLIPKNNPPQLTG-SYTKSFKDFVEACLNKDPENRPTAKELLKYPFIKK--AKKNAYLIDLIDRFKKWKV---------------------------SKGDESETES----------------------------------ENSDSDSDAKQGGSSQDEPWIMTVKGLHINSAPRAGVNSFQLQEHELTMQKLMQTTHSPAGGGGVQASPAANALSSSVSAVAASASSVSVITANEG-------------------------VSSASALPPQNSHVHNHNHNNINNNN------IRNLSNKHA--------------------------------------------TTTMLNAAPPPSSVTSSSSASELQQKRSSSKPELRQSRSAAPLDQVEDRRASLGLPLQSSVPTPSTAEQQQQRRSSQRESFHANNAALVASCSSSSNNHSHEEHVATNHASHVKHSGAGQRLVQT------------------------------------------------NSACLNNFLFP--------------------------------------------VLSDIQRKYSGGGSAGSGGS------GGRNIGVGSDIGDLKSVFELAERSSPGVSDLFMKELIHMLVPGYSETRINTIMDRAIRNRK---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P38692-1", "uniprot_id": "KIC1_YEAST", "id": "P38692-1", "name": "Serine/threonine-protein kinase KIC1", "aln": "MTTKPQNSKQGLAEGEMDVSSLFKRTEVIGRGKFGVVYKGYNVKTGRVYAIKVLNLDSDSDEVEDVQREIQFLASLKQISNITRYYGSYLKDTSLWIIMEHCAGGSLRSLLRPGKIDEKYIGVIMRELLVALKCIHKDNVIHRDIKAANVLITNEGNVKLCDFGVAAQVNQTSLRRQTMAGTPYWMAPEVIMEGVYYDTKVDIWSLGITTYEIATGNPPYCDVEALRAMQLIIKSKPPRLEDRSYSTSLKEFIALCLDEDPKERLSADDLLKSKFIRAHKATPTSILKELISRYLLFRDKNKNKYKIEGSIPENEPSKPSEAPKPSQNGGGDEAQKSIASNDNEIKRVNEGDVEMKWDFDSLSSSDYIIENNINLDALAEDNNEWATAQHDLFNYAYPDEDSYYFDPTSHNTRPFVYQGTTIGKGYPGTIAQNSTLNAPVTNNYTNSKYPSKMVAGTTNTSGTHTAGPMTSSKRLESKAPKQLLELFEDNEIITAENDVNTEAPKISKSISSLNAGNSSRDDFIPSISNEVNGNINNNKMRPHLPPLSSGNNYYSQSTPALPLLQTKFNKTSKGPPTSGLTTAPTSIEIEIPEELPNSALPTPASADPVLIPSTKARSSTVTAGTPSSSSSIQYKSPSNVPRRLTVSNNRPEHCPSTITNQKLGSAVASNSGISSTPNNSNNYNNNTDSENSRGSSGSNTANSTQMGITNPGNVTKLSTHKASSPSRPLFGVGTSPNRKPAGSPTQNIGHNSTHTNLAPPPTMKPMANSKDNKDILLQPLNSIPSSSTLNTISGNSSNNLTSSNYFSNEKEGSRVNGDFKRNNPNLKLQMPLPTPVVRNKLLDPNTATSQNNNGMPGSAGISTNENINQFGFNTSSASNIPVSMTPISEKHIDFGGKIKRSQSISNRKNSSASEHPLNILGSSVSGNVSGIGNNNVGSNNNSGPNNSVPLSANTGNTTIKANSTTIATSSSAAASTTAPISQQTIPSGTQFNHILSSAATAANSVNSLGFGMCPPPQSLQMEMFLDLESFLPGKQRRVDRKPQVLKELENLLQMFEEGLPCIEHALKEQLISTPIKDNEH", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .:: . *.: : **:*.** *:** : :* .* ***:::*:. .**::*:*:** .*:. .. :*:*:**:*..:.******: .*** .*::.* ::* :*. *:**:* .*. :*.:. :**********:::.*:***.*****.*:.:* :*:*:.***:******* : ** *.********: *:*.*:** .::..:*.: ** *..** * . ::..:*:*: **:::*. * :*.:*** ** :. .: * :**.*: :: .:* .*:.. :: : *. ..: . . * : : ..:: . .:: .:. . . ..: * : : :. .*. * : : :.. . :.. ** :. . :. . : ", "identical_positions": 127, "similar_positions": 165, "identity": "11.76%" }, { "cls_id": "homologset.agr.MGI:1891700", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8CGU6-1", "uniprot_id": "NICA_RAT", "id": "Q8CGU6-1", "name": "Nicastrin", "aln": "MATARGGSGPDPGSRGLL-LLSFSVVLAGLCGGNSVERKIYIPLNKTAPCVRLLNATHQIGCQSSISGDTGVIHVVEKEDDLKWVLTDGPNPPYMVLLEGKLFTRDIMEKLKGETSRIAGLAVTLAKPNSTSSFSPSVQCPNDGFGIYSNSYGPEFAHCKKTLWNELGNGLAYDDFSFPIFLLEDENETKVIKQCYQDHNLGQNGSAPSFPLCAMQLFSHMHAVISTATCMRRSFIQSTFSINPEIVCDPLSDYNVWSMLKP-----INTSGGLEPDVRVVVAATRLDSRSFFWNVAPGAESAVASFVTQLAAAEALHKAP-DVTTLPRNVMFVFFQGETFDYIGSSRMVYDMENGKFPVRLENID--SFVELGQVALRTSLELWMHTDPMSQKNESVKNQVEDLLVTLEQSGADTPQVVLSRLVQSQALPPSSLQRFLR-ARNISGVVLADHSGSFHNRYYQSIYDTAENINVTYPESQSPEEDLNFVTDTAKALAD--------VATVLARALYKLAGGTNFNNSIQADPQTVTRLLYGFLVRANNSWFQSILRHDLRSYLDDGPLQHYIAVSSPTNTTYVVQYALAN--LTGKVTNLTQEQCQDPSKVPNESKDLYEYSWVQGPWNSNKTERLPRCVRSTVRLARALSPAFELS--QWSSTEYSTWAESRWKDIQARIFLIASKELEFITLIVGFSILVFSLIVTYCINAKADVLFVAPREPGAVSY-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P57716-1", "uniprot_id": "NICA_MOUSE", "id": "P57716-1", "name": "Nicastrin", "aln": "MATTRGGSGPDPGSRGLL-LLSFSVVLAGLCGGNSVERKIYIPLNKTAPCVRLLNATHQIGCQSSISGDTGVIHVVEKEEDLKWVLTDGPNPPYMVLLEGKLFTRDVMEKLKGTTSRIAGLAVTLAKPNSTSSFSPSVQCPNDGFGIYSNSYGPEFAHCKKTLWNELGNGLAYEDFSFPIFLLEDENETKVIKQCYQDHNLGQNGSAPSFPLCAMQLFSHMHAVISTATCMRRSFIQSTFSINPEIVCDPLSDYNVWSMLKP-----INTSVGLEPDVRVVVAATRLDSRSFFWNVAPGAESAVASFVTQLAAAEALHKAP-DVTTLSRNVMFVFFQGETFDYIGSSRMVYDMENGKFPVRLENID--SFVELGQVALRTSLDLWMHTDPMSQKNESVKNQVEDLLATLEKSGAGVPEVVLRRLAQSQALPPSSLQRFLR-ARNISGVVLADHSGSFHNRYYQSIYDTAENINVTYPEWQSPEEDLNFVTDTAKALAN--------VATVLARALYELAGGTNFSSSIQADPQTVTRLLYGFLVRANNSWFQSILKHDLRSYLDDRPLQHYIAVSSPTNTTYVVQYALAN--LTGKATNLTREQCQDPSKVPNESKDLYEYSWVQGPWNSNRTERLPQCVRSTVRLARALSPAFELS--QWSSTEYSTWAESRWKDIQARIFLIASKELEFITLIVGFSTLVFSLIVTYCINAKADVLFVAPREPGAVSY-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q92542-1", "uniprot_id": "NICA_HUMAN", "id": "Q92542-1", "name": "Nicastrin", "aln": "MATAGGGSGADPGSRGLLRLLSFCVLLAGLCRGNSVERKIYIPLNKTAPCVRLLNATHQIGCQSSISGDTGVIHVVEKEEDLQWVLTDGPNPPYMVLLESKHFTRDLMEKLKGRTSRIAGLAVSLTKPSPASGFSPSVQCPNDGFGVYSNSYGPEFAHCREIQWNSLGNGLAYEDFSFPIFLLEDENETKVIKQCYQDHNLSQNGSAPTFPLCAMQLFSHMHAVISTATCMRRSSIQSTFSINPEIVCDPLSDYNVWSMLKP-----INTTGTLKPDDRVVVAATRLDSRSFFWNVAPGAESAVASFVTQLAAAEALQKAP-DVTTLPRNVMFVFFQGETFDYIGSSRMVYDMEKGKFPVQLENVD--SFVELGQVALRTSLELWMHTDPVSQKNESVRNQVEDLLATLEKSGAGVPAVILRRPNQSQPLPPSSLQRFLR-ARNISGVVLADHSGAFHNKYYQSIYDTAENINVSYPEWLSPEEDLNFVTDTAKALAD--------VATVLGRALYELAGGTNFSDTVQADPQTVTRLLYGFLIKANNSWFQSILRQDLRSYLGDGPLQHYIAVSSPTNTTYVVQYALAN--LTGTVVNLTREQCQDPSKVPSENKDLYEYSWVQGPLHSNETDRLPRCVRSTARLARALSPAFELS--QWSSTEYSTWTESRWKDIRARIFLIASKELELITLTVGFGILIFSLIVTYCINAKADVLFIAPREPGAVSY-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VC27-1", "uniprot_id": "NICA_DROME", "id": "Q9VC27-1", "name": "Nicastrin", "aln": "---------MEMRLNAASIWLLILSYGATIAQGERTRDKMYEPIGG-ASCFRRLNGTHQTGCSSTYSGSVGVLHLINVEADLEFLLSSPPSPPYAPMIPPHLFTRNNLMRLKEAGPKNISVVLLINRTNQMKQFSHELNCPNQYSGLNSTSETCDASNPAKN-WNPWGTGLLHEDFPFPIYYIADLDQVTKLEKCFQDFNNHNYETHALRSLCAVEVKSFMSAAVNTEVCMRRTNFIN--NLGGSKYCDPLEGRNVYATLYPRKPAIENNLETVHTNEKFILVTCRLDTTTMFDGVGLGAMDSLMGFAVFTHVAYLLKQLLPPQSKDLHNVLFVTFNGESYDYIGSQRFVYDMEKLQFPTESTGTPPIAFDNIDFMLDIGTLDDISNIKLHALNGTTLAQQILERLNNYAKSPRYGFNLNIQS-EMSAHLPPTSAQSFLRRDPNFNALILNARP---TNKYYHSIYDDADNVDFTYANTSKDFTQLTEVNDFKSLNPDSLQMKVRNVSSIVAMALYQTITGKEYTGTKVANPLMADEFLYCFLQSADCPLFKAASYPGSQ--LTNLPPMRYISVLGGSQESSGYTYRLLGYLLSQLQPDIHRDNCTDLP--------LHYFAGFN---------NIGECRLTTQNYSHALSPAFLIDGYDWSSGMYSTWTESTWSQFSARIFLRPSNVHQVTTLSVGIVVLIISFCLVYIISSRSEVLFEDLPASNAALFG", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : .. * : * :. *: .. *:* *:. *.*.* **.*** **.*: **..**:*::: * **:::*:. *.*** :: : ***: : :** .: .:.: : :.. . ** .::***: *: *.* : :: : ** *.** ::**.***: : * ::.. :::*:**.* : : . .***::: *.* *.:.* .****: : . .:. . ****.. **:: * * *. :..: :.::.: ***: ::* .*. ** .:: .*.. .* *:: :. :**:** *:**::*****.*:*****: :**.. . :* ::. : :*: : . : :. :: :*: : * . :* : : * ***:* * *** *:..::* :. *:**:**** *:*::.:*.: . :*. *.* . .: *::::. ***: *.::..: *:* . .:** ** *: . *:: . : * : * :**:* . :: : * * . *: :: :::* * . *: :: .: .: .* :* . ::****** :. :*** ****:** *.:: ***** .*: :. ** **: *::*: :.* *.::::*** ..*. : ", "identical_positions": 197, "similar_positions": 253, "identity": "26.95%" }, { "cls_id": "homologset.agr.MGI:1891701", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P59382-1", "uniprot_id": "PXMP4_RAT", "id": "P59382-1", "name": "Peroxisomal membrane protein 4", "aln": "MAAPPQLRALLQAVNKLLRQRRYHAALAVIKGFRNGAVYGVKIRAPHALVMTFLFRSGSLQEKLQAILKATYTHSRNLACFVFTYKSLQALQSHVQGGTHQMHSFLAAFIGGLLLFGENNNINSQINMYLTSRVLFALCRLGVEKGYIPALKWDPFPLHTAVIWGLVLWLFEYHRPTLQPSLQSSMTYLYEDSNVWHDLSDFLIFNKSRPSK", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9JJW0-1", "uniprot_id": "PXMP4_MOUSE", "id": "Q9JJW0-1", "name": "Peroxisomal membrane protein 4", "aln": "MAAPPQLQALLQAVNKLLRQRRYHAALAVIKGFRNGAVYGVKIRAPHALVMTFLFRSGSLREKLQAILKATYIHSRNLACFVFAYKSLHALQSHVQGETHQMHSFLAAFIGGLLLFGENNNINSQINMYLTSRVLYALCRLGVEKGYIPALKWDPFPLHTAVIWGLVLWLFEYHRPTLQPSLQSSMTYLYEDSNVWHDLSDFLIFNKSHPSK", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9Y6I8-1", "uniprot_id": "PXMP4_HUMAN", "id": "Q9Y6I8-1", "name": "Peroxisomal membrane protein 4", "aln": "MAAPPQLRALLVVVNALLRKRRYHAALAVLKGFRNGAVYGAKIRAPHALVMTFLFRNGSLQEKLWAILQATYIHSWNLARFVFTYKGLRALQSYIQGKTYPAHAFLAAFLGGILVFGENNNINSQINMYLLSRVLFALSRLAVEKGYIPEPRWDPFPLLTAVVWGLVLWLFEYHRSTLQPSLQSSMTYLYEDSNVWHDISDFLVYNKSRPSN", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A2R8QFW3-1", "uniprot_id": "A0A2R8QFW3_DANRE", "id": "A0A2R8QFW3-1", "name": "Peroxisomal membrane protein 4", "aln": "MAASDLFKTLLYTVNNLLQQHKYKTALAVLKGFRNGAVYGAKIRAPHALVMTFLFRSGSLREKFRAIAQATYTHSRNLACFVFTYKGLQALQQQLQGKQMQSHSFLAACVGGWLVFGENNNINSQINMYLLSRILFALSRLAVEKGLIPQPKKDPFPLFATLVWGIVLWLFEYYPHTLQPSLQSSMNYLYHDSNTWHDITDSLIYNKPKAN-", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "***. :::** .** **::::*::****:**********.***************.***:**: ** :*** ** *** ***:**.*:***. :** *:**** :** *:*************** **:*:**.**.**** ** : ***** ::::**:*******: **********.***.***.***::* *::**.:.. ", "identical_positions": 138, "similar_positions": 47, "identity": "65.09%" }, { "cls_id": "homologset.agr.MGI:1891702", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I6A9R8-1", "uniprot_id": "A0A8I6A9R8_RAT", "id": "A0A8I6A9R8-1", "name": "Coatomer subunit epsilon", "aln": "MAPPAPGAVSGSSGEVDELFDVKNAFYIGSYQQCINEAQRVKLSSPEREVERDVFLYRAYLAQRKYGVVLDEIKPSSAPELQAVRMFAEYLASENRRDSIVLELDREMSRSVDVTNTTFLLMAASIYFHDQNP--DAALRTLHQG---DGLECTAMTIQILLKLDRLDLARKELKRMQEQDEDAT------LTQLATAWVNLAMGGEKLQEAYYIFQELADKCSPTLLLLNGQAACHSAQGRWETAEGVLQEALDKDS----------GHPETLINLIVLSQHLGKPPEVTNRYLSQLKDAHRTHPFIKEYQAKENDFDRLALQYAPSA-------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O89079-1", "uniprot_id": "COPE_MOUSE", "id": "O89079-1", "name": "Coatomer subunit epsilon", "aln": "MAPPVPGAVSGGSGEVDELFDVKNAFYIGSYQQCINEAQRVKLSSPEREVERDVFLYRAYLAQRKYGVVLDEIKPSSAPELQAVRMFAEYLASENQRDSIVLELDREMSRSVDVTNTTFLLMAASIYFHDQNP--DAALRTLHQG---DGLECMAMTIQILLKLDRLDLARKELKKMQDQDEDAT------LTQLATAWVNLAVGGEKLQEAYYIFQELADKCSPTLLLLNGQAACHSAQGRWETAEGVLQEALDKDS----------GHPETLINLIVLSQHLGKPPEVTNRYLSQLKDAHRAHPFIKEYQAKENDFDRLAMQYAPSA-------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O14579-1", "uniprot_id": "COPE_HUMAN", "id": "O14579-1", "name": "Coatomer subunit epsilon", "aln": "MAPPAPGPASGGSGEVDELFDVKNAFYIGSYQQCINEAQRVKLSSPERDVERDVFLYRAYLAQRKFGVVLDEIKPSSAPELQAVRMFADYLAHESRRDSIVAELDREMSRSVDVTNTTFLLMAASIYLHDQNP--DAALRALHQG---DSLECTAMTVQILLKLDRLDLARKELKRMQDLDEDAT------LTQLATAWVSLATGGEKLQDAYYIFQEMADKCSPTLLLLNGQAACHMAQGRWEAAEGLLQEALDKDS----------GYPETLVNLIVLSQHLGKPPEVTNRYLSQLKDAHRSHPFIKEYQAKENDFDRLVLQYAPSA-------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9Y0Y5-1", "uniprot_id": "Q9Y0Y5_DROME", "id": "Q9Y0Y5-1", "name": "Coatomer subunit epsilon", "aln": "MSRQQNEEDTNS-----VLFDARNEYYIGNFMGSINFVLPEQGTAGP---ELLSYMYLSYLAIDSGRIVASDIKEGNSTPLQALRLVHEAFEQPSRTEELLEKLTDKVAGEEDETN-IWHLATAIVYCHDGQF--ENALKILHGS---TNLESMALSVQCLLRLQRVDLAKQLVAKMQEISDDAT------LTQLAQAWVALAQGTEQMQDAFHIYQEFCEKFKPTPALLNGQAVVHLGLERYEEADSVLRESLLKKH----------NDYDTLINLMVHAHLTGKPTEAITRNLEQLRQFYPKSDFVTDLDKKSAEFDRLCLQYDVEGGEKLLAV", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P40509-1", "uniprot_id": "COPE_YEAST", "id": "P40509-1", "name": "Coatomer subunit epsilon", "aln": "----------------MDYFNIKQNYYTGNFVQCLQEIEKFSKVTDN---TLLFYKAKTLLALGQYQSQDPTSKLG-----KVLDLYVQFLDTKN-----IEELENLLKDKQNSPYELYLLATAQAILGDLDKSLETCVEGIDNDEAEGTTELLLLAIEVALLNNNVSTASTIFDNYTNAIEDTVSGDNEMILNLAESYIKFATNKETATSNFYYYEELSQTF-PTWKTQLGLLNLHLQQRNIAEAQGIVELLLSDYYSVEQKENAVLYKPTFLANQITLALMQGLDTEDLTN---QLVKLDHEHAFIKHHQEIDAKFDELVRKYDTSN-------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *: :: :* *.: .:: . : : : ** . * . :.: : : : . : :* : . : . : * :* * : : .:. :. . * :::: * :.:. * . . : :*:. : :** ::: :* . * . :: ::*:.:. ** * * . *:.::. * . * * :. : * .* .. ** . *:.. : . .**.* :* . ", "identical_positions": 36, "similar_positions": 91, "identity": "10.71%" }, { "cls_id": "homologset.agr.MGI:1891703", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZRJ6-1", "uniprot_id": "D3ZRJ6_RAT", "id": "D3ZRJ6-1", "name": "Cell surface A33 antigen", "aln": "--MLGTVGPVLWMFCAIWVAADAITVETTQDVLRAARGKSVTLPCIYSTP----VSDRQGFIQWDKLLRSQTEKVATWTFETKKYTYGSRYENRVRISNDAELSNASITIDQLTMDDNGTYECSVSLMSDQDVTSRSRVRLLVLVPPSKPDCGIEGETVIGNNIQLTCHSAEGSPSPQYSWKSYNAQNQQRP--LAQPVSGEPLLLKNISADTAGYYICTSSNDVGTEFCNITVAPRPPSMNIALYAGIAGGVFVALIIIGVIVYCCCCREK-------------------------------------------------------------DDKAQEMETVRPDRAAYQEPKNQRTEISREWEDEDDRRHEDQRSSGRGSPDQPFQ--------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9JKA5-1", "uniprot_id": "GPA33_MOUSE", "id": "Q9JKA5-1", "name": "Cell surface A33 antigen", "aln": "--MLGKAGSVVWMLCAIWVAADALTVETTQDILRAARGRSVTLPCTYNTY----VSDREGFIQWDKLLRSQTERVVTWNFVTKKYIYGNRYENRVRVSNDAELSNASITIDQLTMDDNGTYECSVSLMSDQDVNAKSRVRLLVLVPPSKPDCSIQGEMVIGNNIQLTCHSAEGSPSPQYSWKSYNAQNQQRP--LTQPVSGEPLLLKNISTETAGYYICTSSNDVGIESCNITVAPRPPSMNIALYAGIAGGVFVALIIIGVIVYCCCCREK-------------------------------------------------------------DDKDQDREDARPNRAAYQVPKKEQKEISRGREDEDDHRHEDRWSSGRSTPDQPFQ--------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q99795-1", "uniprot_id": "GPA33_HUMAN", "id": "Q99795-1", "name": "Cell surface A33 antigen", "aln": "--MVGKMWPVLWTLCAVRVTVDAISVETPQDVLRASQGKSVTLPCTYHTS----TSSREGLIQWDKLLLTHTERVVIWPFSNKNYIHGELYKNRVSISNNAEQSDASITIDQLTMADNGTYECSVSLMSDLEGNTKSRVRLLVLVPPSKPECGIEGETIIGNNIQLTCQSKEGSPTPQYSWKRYNILNQEQP--LAQPASGQPVSLKNISTDTSGYYICTSSNEEGTQFCNITVAVRSPSMNVALYVGIAVGVVAALIIIGIIIYCCCCRGK-------------------------------------------------------------DDNTEDKEDARPNREAYEEPPEQLRELSREREEEDDYRQEEQRSTGRESPDHLDQ--------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A0R4IIH3-1", "uniprot_id": "A0A0R4IIH3_DANRE", "id": "A0A0R4IIH3-1", "name": "", "aln": "MADTLRLLGFILLSAGLHVASAAIVVDIPQKQYKVARGDNATLPCAFTPPPPAGSTTEITWKATPDVPGSPMIDIIKFNSATGMKVYKN-YKGRAGLTFDLTKGKADLQLVRVTSADNRTYECHVDVQEEEDGTLSDTANLIVLVAPSTPKCTIEGKTEYFQDITLTCKSEEGTPTPTYKWQSYDVLNNPRPNPLKATDVNGVLSLYNISKDTSGFYVCTSTNEIRSAKCNLTMAVMAPSMSMASTAGIIGAAAGALVLLLVIIICCCCCRRKKNKEEEYAMGTPEDGEFTDKDPEEQDEHVRSEQERPVKSADRRDVQDERSERSYDRRSDYDDRRDPNTSQRDDRDDRYNDRRDRYDDKRDRSDDRQERYDDRRERNGDRQDRYDDRRDRNDDRRDRYDDRYDDRRDRYDDRRDRHDDRYDSDRYSDRYDSRDRPPSVPPNKPRDPRN", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .: ..: *: *: *: .*. :.::* ..**** : . : . .: : : : . : . *:.*. :: : ..*.: : ::* ** **** *.: .: : . . ..*:***.**.*.* *:*: ::* ***:* **:*:* *.*: *: *: :* * . . : * *** :*:*:*:***:*: **:*:* .***.:* .** .. **::: :*: **** : **. : * :* .: : .* .:: : * ::: . . *: : ", "identical_positions": 80, "similar_positions": 107, "identity": "17.78%" }, { "cls_id": "homologset.agr.MGI:1891704", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q69ZS7-1", "uniprot_id": "HBS1L_MOUSE", "id": "Q69ZS7-1", "name": "HBS1-like protein", "aln": "MARHRNVRGYNYDEDFE-DDDLYGQSVEDDYCISPSTAAQFIYSRRDNP-------------EEEYGYEDLRE---------SSNSLLNHQLSEIDQARLYSCLDHMREVLGDAVPDDILTEAILKHKFDVQKALSVVLEQDG-VQPWKEKSE---RAVCAGQPSKGKSVISRSSQSESEIVPKVAKMTVSGKKQTMGFEVPGLTSEENGLSVRAPHKGPPGDDVSVASPNIPETGTPKSALPPPSLQTSEELGSTPTPVRKSGKLRQQIDVKAELEK-RQGGKQLLNLVVIGHVDAGKSTLMGHMLYLLGNVNKRTMHKYEQESKKAGKASFAYAWVLDETGEERERGVTMDVGMTKFETTTKVITLMDAPGHKDFIPNMITGAAQADVAVLVVDASRGEFEAGFETGGQTREHGLLVRSLGVTQLAVAVNKMDQVNWQQERFQEITGKLGHFLKQAGFKESDVAFIPTSGLSGENLTARSQSSDLTTWYKGMCLLEQID--SFKPPQRS----IDKPFRLCVSDVFKDQGSG---FCVTGKIEAGYIQTGDRLLAMPPNETCTAKGITLHDEP--------VDWAAAGDHVNLTLVGMDIIKINVGCIFCGPKEP-IKACTRFRARILVFNIEVPITKGFPVLLHYQTVSEPAVIKRLISVLNKSTGEVTKKKPKLLTKGQNALVELQTQRP---VALELYKDFKELGRFMLRYGGSTVAAGVVTEIKE", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6AXM7-1", "uniprot_id": "HBS1L_RAT", "id": "Q6AXM7-1", "name": "HBS1-like protein", "aln": "MARHRNVRGYNYDEDFE-DDDLYGQSVEDDYCISPSTAAQFIYSRRDNP-------------EEEYGYEDLKE---------SSNSLLNHQLSEIDQARLYSCLDHMREVLGDAVPDDILTEAILKHKFDVQKALSVVLEQDG-VQTLKEKSE---RAVCAGQPSK---VISRSSQSESEIVPKVAKMTVSGKKQTMGFEVPGLPSEENGHNVRAPYKGPPGDDVSIASPNVPETGTPKSTAHPPSLQTSEELGCTPTPLRKSGKLRQQIDVKAGLEK-RQGGKQLLNLVVIGHVDAGKSTLMGHMLYLLGNVNKRTMHKYEQESKKAGKASFAYAWVLDETGEERERGVTMDVGMTKFETTTKVVTLMDAPGHKDFIPNMITGAAQADVAVLVVDASRGEFEAGFETGGQTREHGLLVRSLGVTQLAVAVNKMDQVNWQQERFQEITGKLGHFLKQAGFKESDVAFIPTSGLSGENLTSRSQSSDLTKWYKGLCLLEQID--SFKPPQRS----IDKPFRLCVSDVFKDQGSG---FCVTGKIEAGYVQTGDRLLAMPPNETCTAKGITLHDEP--------VDWAAAGDHVSLTLVGMDIIKINVGCIFCGPKEP-IKACTRFRARILIFNIEVPITKGFPVLLHYQTVSEPAVIKRLISVLNKSTGEVTKKKPKLLTKGQNALVELQTQRP---VALELYKDFKELGRFMLRYGGSTVAAGVVTEIKE", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9Y450-1", "uniprot_id": "HBS1L_HUMAN", "id": "Q9Y450-1", "name": "HBS1-like protein", "aln": "MARHRNVRGYNYDEDFE-DDDLYGQSVEDDYCISPSTAAQFIYSRRDKPSV---------EPVEEYDYEDLKE---------SSNSVSNHQLSGFDQARLYSCLDHMREVLGDAVPDEILIEAVLKNKFDVQKALSGVLEQDR-VQSLKDKNE---ATVSTGKIAKGKPVDSQTSRSESEIVPKVAKMTVSGKKQTMGFEVPGVSSEENGHSFHTPQKGPPIEDA-IASSDVLETAS-KSANPPHTIQASEEQSSTPAPVKKSGKLRQQIDVKAELEK-RQGGKQLLNLVVIGHVDAGKSTLMGHMLYLLGNINKRTMHKYEQESKKAGKASFAYAWVLDETGEERERGVTMDVGMTKFETTTKVITLMDAPGHKDFIPNMITGAAQADVAVLVVDASRGEFEAGFETGGQTREHGLLVRSLGVTQLAVAVNKMDQVNWQQERFQEITGKLGHFLKQAGFKESDVGFIPTSGLSGENLITRSQSSELTKWYKGLCLLEQID--SFKPPQRS----IDKPFRLCVSDVFKDQGSG---FCITGKIEAGYIQTGDRLLAMPPNETCTVKGITLHDEP--------VDWAAAGDHVSLTLVGMDIIKINVGCIFCGPKVP-IKACTRFRARILIFNIEIPITKGFPVLLHYQTVSEPAVIKRLISVLNKSTGEVTKKKPKFLTKGQNALVELQTQRP---IALELYKDFKELGRFMLRYGGSTIAAGVVTEIKE", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F1Q5Z6-1", "uniprot_id": "F1Q5Z6_DANRE", "id": "F1Q5Z6-1", "name": "HBS1-like protein", "aln": "MSRHRNVRGYNYDEDFE-DDDMYGQSVEDDYCISPATAAQFIYSRQDSRQAR------HVETVEEAEYEEEEEEM-------PTSPTMTSTLDSLQQGRLYSCLDQMRTVLGDSIPDSTLTQAALKYDCDPHRALDFILSENTNTQAPSARTNPQLEPNTTAAPQKAKVREAPESRVESEVVPKVARMTVSGKKQTMGFDVR--SAEENGGVAPSLRRGPS-----------PEATAVPTTETPSKQSTVTEDSAAPTPTRPSGKSKQQLNIRAELEK-RQGGKPLLNLVVIGHVDAGKSTLMGHLLYLLGNVNKRTMHKYEQEAKKAGKASFAYAWVLDETGEERDRGVTMDVGMTKFETDSKVVTLMDAPGHKDFIPNMITGAAQADVAVLVVDASRGEFEAGFEAGGQTREHALLVRSLGVTQLAVAVNKMDQVNWQQERFQEIISKLGHFLKQAGFKDSDVFYVPTSGLSGENLTTKSKVADLTAWYTGPCLVEQID--AFKPPQRS----VEKPFRLCVSDVFKDQGSG---FCVTGKIEAGYIQTGDKVLAMPPNETCTVKGISLHDEA--------LDWAAAGDHVSLTVTGMDIIKINVGCVFCDPKEP-IRACTRFRARILLFNIELPITQGFPVLLHYQTVSEPATIRKLVSVLHKSSGEVLKKKPKCLSKGQNAVVEIQTQRP---VAMELYKDYKELGRFMLRYVGSTIAAGVVTEIKE", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9W074-1", "uniprot_id": "HBS1_DROME", "id": "Q9W074-1", "name": "Protein HBS1", "aln": "MSRHRIVRTMDYNDEYDGYDDIYGHSVEDEHCISPTDAQQWLYDRARGQQSISAFISKNKDIQEEEADEDEDEDAAFAKARRDSESFQMPQLDEIEQAKLSSCVDEVRSVVGDAVSERRIVETSMKFDYDMQKILDEILNEET-NKSAKPAVN-------------------KMKAPAAPVLPKTVSKTVPTPPPKISLKEP-----RRGFEIPSPK--------------VPSSPVVSGRNTPVDISAGDDISRSSATVFKVSKEQAVRNARQLYEKERADQKSHIHMIVIGHVDAGKSTLMGHLLYDTGNVSQRVMHKHEQESKKLGKQSFMYAWVLDETGEERARGITMDVGQSRIETKTKIVTLLDAPGHKDFIPNMISGATQADVALLVVDATRGEFESGFELGGQTREHAILVRSLGVNQLGVVINKLDTVGWSQDRFTEIVTKLKSFLKLAGFKDSDVSFTPCSGLTGENLTKKAQEPALTNWYSGRHLLDVIE--NFKIPERA----IDRPLRMSVSDIYKGTGSG---FCISGRVETGVLCLNDKVLVGASREQAQVKSLTMNEFP--------QTCVFAGDQVSVTLPALDINNVTVGCIISDPQTP-IPVTTRFQARIIVFNVKVPITMGFPVLLHHQSLIEPAVVCKLTASIHKSTGEVVKKKPRCLGNNSCALVELETSRP---ICIERYADFKELGRVMLRVAGVTIAAGMVTKIR-", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P32769-1", "uniprot_id": "HBS1_YEAST", "id": "P32769-1", "name": "Elongation factor 1 alpha-like protein", "aln": "MAYSDYSDGADDMPDFHDEGEFDDYLNDDEYDLMN-----------------------------------------------EVFPTLKAQLQDYQG-----------------WDNLSLKLALFDNNFDLESTLAELKKTLKKKKTPKKPIA--------------------AANGSANVTQKLANISISQQRPND-----------------------------------RLPDWLDEEESEGERNGEEANDEKTVQRYYKTTVPTKPKKPHDISAFVKSALPHLSFVVLGHVDAGKSTLMGRLLYDLNIVNQSQLRKLQRESETMGKSSFKFAWIMDQTNEERERGVTVSICTSHFSTHRANFTIVDAPGHRDFVPNAIMGISQADMAILCVDCSTNAFESGFDLDGQTKEHMLLASSLGIHNLIIAMNKMDNVDWSQQRFEEIKSKLLPYLVDIGFFEDNINWVPISGFSGEGVYKIEYTDEVRQWYNGPNLMSTLENAAFKISKENEGINKDDPFLFSVLEIIPSKKTSNDLALVSGKLESGSIQPGESLTIYPSEQSCIVDKIQVGSQQGQSTNHEETDVAIKGDFVTLKLRKAYPEDIQNGDLAASVDYSSIHSAQCFVLELTTFDMNRPLLPGTPFILFIGVKEQPARIKRLISFIDKGN-TASKKKIRHLGSKQRAFVEIELIEVKRWIPLLTAHENDRLGRVVLRKDGRTIAAGKISEITQ", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*: : ::. .:: . :*:: : . *. : : : : :. . * . * : . :. . : : * . ::. . . . . .. . . . . : ::*:************::** . :.: ::* ::*::. ** ** :**::*:*.*** **:*:.: :::.* .*::*****:**:** * * :***:*:* **.: . **:**: .***:** :*. ***: :* :.:**:* *.*.*:** ** ** :* ** :.:: : * **::**.: : **.* *:. :: ** .:. : *: :.* :: . :. ::*::*:* : .: : ...: . .. : : . . ** *.:.: .: * : .. . . * * .: *::: *: * *.:*. :** : :* : :.*.. . *** : * . . *.**:: . : : : ..***.:** * *:*** :::* ", "identical_positions": 135, "similar_positions": 195, "identity": "18.47%" }, { "cls_id": "homologset.agr.MGI:1891705", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZCI9-1", "uniprot_id": "D3ZCI9_RAT", "id": "D3ZCI9-1", "name": "", "aln": "MKLGSQEPGSARSWAYSSAREVGVSSSPEPGTLSWGLRNSNFWAPRCPVSIPAPGRMLSFFLLTIPSSQAPRRARKRVEG-----TASSNVFSMFDQSQIQEFKE----------------------------------AFTIMDQNRDGFIDKEDLRDTFAALGRINVKNEELEAMVKEAPGPINFTVFLTMFGEKLKG---TDPEETILHAFKVFDTEGKGFVKADFIKEKLMTQADRFSEEEVKQMFAAFPPDVCGNLDYRNLCYVIT-HGEEKD----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q62082-1", "uniprot_id": "MYL10_MOUSE", "id": "Q62082-1", "name": "Myosin regulatory light chain 10", "aln": "--MGQ------------SSLDHGVQG-PVAGTGDFGPLK----------EATATG--------FISCAQAPRRARKRVEG-----TASSNVFSMFDQSQIQEFKE----------------------------------AFTIMDQNRDGFIDKEDLRDTFAALGRINVKNEELEAMVKEAPGPINFTVFLTMFGEKLKG---TDPEETILHAFKVFDTEGKGFVKADFIKEKLMTQADRFSEEEVKQMFAAFPPDVCGNLDYRNLCYVIT-HGEEKD----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9BUA6-1", "uniprot_id": "MYL10_HUMAN", "id": "Q9BUA6-1", "name": "Myosin regulatory light chain 10", "aln": "-----------------MLLRLVSNSWPQVILPPR--------PPK------------------VLGLQAPRRARKRAEG-----TASSNVFSMFDQSQIQEFKESLALSPRLERNGMISAHCNLCLTGSSNSPASASQAFTIMDQNRDGFIDKEDLRDTFAALGRINVKNEELEAMVKEAPGPINFTVFLTMFGEKLKG---TDPEETILHAFKVFDTEGKGFVKADVIKEKLMTQADRFSEEEVKQMFAAFPPDVCGNLDYRNLCYVIT-HGEEKD----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P18432-1", "uniprot_id": "MLR_DROME", "id": "P18432-1", "name": "Myosin regulatory light chain 2", "aln": "MADEKKKVKKKKTKEEGGTSETASEAASEAATPAPAATP-----------------------APAASATGSKRASGGSRGSRKSKRAGSSVFSVFSQKQIAEFKE----------------------------------AFQLMDADKDGIIGKNDLRAAFDSVGKIAN-DKELDAMLGEASGPINFTQLLTLFANRMATSGANDEDEVVIAAFKTFDNDG--LIDGDKFREMLMNFGDKFTMKEVDDAYDQMVIDDKNQIDTAALIEMLTGKGEEEEEEAA", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .. . ..:** .* *.*.***:*.*.** **** ** :** ::**:*.*:*** :* ::*:* ::**:**: **.****** :**:*.::: .* :*.:: ***.**.:* ::..* ::* **. .*:*: :**.: : : * .::* * ::* :***:: ", "identical_positions": 68, "similar_positions": 64, "identity": "24.11%" }, { "cls_id": "homologset.agr.MGI:1891706", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "F1M816-1", "uniprot_id": "F1M816_RAT", "id": "F1M816-1", "name": "Msx2-interacting protein", "aln": "--------------------------------------------------------------------MRRRSARVGFGCLVAAERSCEARESEPGGEGWSLHRGEPEEPPPLPTPPPQPPPPPPRRPPPCADGRVRSRRGGASHGGRRHTAQHGPGNQAPLGGKLTGERARREDHRAFQTAHLELRLAWNLPYSESDFQLLPLSLPPRYGRVESVKILPKRGS-EGGVAAFVDFVDIKSAQKAHNSVNKMGDRDLRTDYNEP-----GTIPSAARG---LDDTVSIASRSREVSGFRGSGGGPAYGPPPSLHAREGRYERRLDGASDNRERAYEHSAYGHHERGTG---AFDRTRHYDQDYYRDPRERTLQHG--------------------------------------------------LYYTSRSRSPNRFDAHDPRYEPRAREQFTLPSVVHRDIYRDDLTREVRGRRPERNYQHSRSRSPHSSQSRNQSPQRLASQASRPTRSPSGSGSRSRSSSSDSISSSSSSS-TDSSDSSSTSSDDSPARSVQSAAVPAPTSQLLS-SLEKDEPRKSFGIKVQNLPVRSTDTSLKDGLFHEFKKFGKVTSVQIHGASEERYGLVFFRQQEDQEKALTASKGKLFFGMQIEVTAWVGPETESENEFRPLDERIDEFHPKATRTLFIGNLEKTTTYHDLRNIFQRFGEIVDIDIKKVNGVPQYAFLQYCDIASVCKAIKKMDGEYLGNNRLKLGFGKSMPTNCVWLDGLSSNVSDQYLTRHFCRYGPVVKVVFDRLKGLALVLYSEIEYAQAAVRETKGRKIGGNKIKVDFANRESQLAFYHCMEKSGQDMRDFYEMLTER---------------------------------------------------------------------------------------------------------------------REERRGSY-DYSQD-----------------RTYYENVRTPGAYPE-------------------------------------------------------------------DSRRDYPARGRE-LYSEWETYQGEYYESRYYDDPR---------------------------------EYREYRSDPYEQDIREYS--------------------------------------------------------------------------------------------YRQRERERERERFESDRD--HERRPIERSQSPVHLRRPQSPGVSPAHSERLPSDSERRLYRR-----------------------------------------------------------------SSERSGSCSSVSPPRYDKLEKARLERYTKNEKTDKER-------------------------------------------------------------------------------------------------------------------------IFDAER---VERERRVIRKEKVEKDKPERQK---------------------------------------------------------------------------------------------------------------------------------------------------------------RKGKVHSPSSQSSETEQENDRDQSPEKPRAST-KLSRDRT----DKEGPAKNRLELVPCVV-LTRVKEKEGKVIDHPPP--EKLKARLAHDTAKSSVLDQKSQASQVEPPKADSSKVDAARGKALREKAFSSHAEVVDKEGRPKLRKHLKPEQ-APELSALDLEKLEARKRRFADSSLKVEKPRPEVRKTSPEAEDTRALLKKQPDTP--RDGILLREGESERKPVRKEILKRESKKTKLERLNSTLSPKDCQEPAAVSAGSGSRPSSDVHAALGEPVHGSVETQE--AQPKKV--MPSKPRLKQLQLLDSQGPEKEEVRKNYCRLREDPVEHKAGQEKPHGVNAEEKLGIDIDHTQSYRKQMEQSRRKQQMEMEIAKSEKFGS-PKKDVDEYERRSLVHEVGKPPQDVTDDSPPSKKRRTD----------------------------------HVDFDICTKRERNYRSSRQISEDSERTSCSPGVHHGSFHEDDDPIGSPRLMSVK---GSPRVDDKGLPYSNVAVREDPFRCTPYDSGKREQAADMAKIKLSVLSSEGEPNRWDPQMKQD----PSRFDVSFPNSIIKRDSLRKRCVRDLEPGEVPSDSDEDAEHRAQSPRASSFYDSPRLSFLLRDRDHKLRDRDDRLSSSLERNKFYSFALDKTITPDTKALLERAKSLSSSREENWSFLDWGSRFANFRDNKDKEKVDSAPRPIPSWYMKKKKIRTDSEGKLDDKKD-------------------EHREEEQERQELFASRFLHSSIFEQDSRRLQHLERKSEESDFPPGRLYGRQASEG------------------ANSTSDSVQEPVVLFHSRFMELT-RMQQKEKEKDQKPKETEKQEGPET-PKTPEPTTE---------------------------------------------------------------------TKEPEPKAPVSVALPAITAVTPEPPPPAAAAEKAEETSEAPSLAGERPEEPTPVLEETKLVSEPPSESVEQRKQVDLSPG---KDSHDSTAVVASTPPE-------STTTDTVPCVDAEPLTPGTTVSQVESSADPKPSSPQPPSKLTQRCEE---------AEEPKVERPETTASIEPDATEKAEVVPEVQPPASEDVEASPPVTAKDRK----------TTKSKRSKTSVPAAAASIVEKPVTRKSERIDREKMKRSSSPRGEAQKLLELKM---------------EADKVTRTASKSSGGDTEHPEPSLPLSRTR-RRNVRSVYATMGDHES--------------------------RSPAKEPTEQPRVTRKRLER--ELQEAVVVPATP------------------------------------------------------------------------------RRGRPPKTRRRVEEGGEQERKEPADTPRPAEGRRSPRSQKLAATGGPQGKRGRNE-----------------------HRAEAAEAT-AQVSAREGNAK-ARGDREAASETRRDRKDPSTDKDGPDIFPVEVE-RKPP-EKTYKSKRGRARSTRSGMDRAAHLKSLEMAR-------QAADKEAEPVAASPEK--NESPLEGSGVSPQLADNPAD-PDKEAEKESVSASTVSPEARQLTKQMELQQAVENIAKLAEPSAAAADKGTATA----------------------------------------------------------------------------------------------------TS----EEPAAEDGHKPAHQASETELAAAIGSIISD-SSGEPENFSASPSVPPGSQTHLQ----------------------EGMEPG-----PHEATPGILETEAATESSAQQ--------------------------------------ASASDPPAGSADTKEARGNSSD---SVQQAKEAK-VAVTPPRKDKGRQKTTRSRRKRNVNKKVAAATETRASEAEQPQSESPAAAAAAAAAAAAAAAAAAAEAEVVVAAA------------------------------------------------------------------------------------------------PPEEPQEEKQSEKPHS-PLRECTSDPSKTPPAESLSQENSVEEKTPCKTPAPPDLPPLSQPALVDDEPQARFKVHSIIESDPVTPP-------------------------------------------SDSSIPPPTIPLVTIAKLPPPVIPG-----GVPHQSPPPKVTEWITRQEEPRAQSAPS---------------------------PALPPDTKASDVDTSSSTLRKILMDPKYVSATG---VTSTSVTAAIAEPVS-APRLQEAPAPPCEPKRPSS-----EEKVAAAVPHADTQASEVPVAADKE----KVAPVIAPKITSVISRMPVSIDLENSQKITLAKPAPQTLTGLVSALTGLVNVSLVPVNALKGPVKGSVATLKGLVSTPAGPVNLLKGPVNVLTGPVNVLTTPVSATVGTVSAAPGTVTAAC------------------------------------------------GVTATTGTAAMSGAVPAPAAKGKQRSSSNENSRFHPGSMSVIDDRPADTGSGAGLRVNTSEG------VVLLSYSGQKTEGPQRISAKISQIPPASAMDIEFQQSVSKSQVKADSVTPTQA-----------------------------------------------APKGPQTPSAFANVAAHSTLVLTAQTYNAS-------------------------------------PVISSVKTDRPSLEKPEPIHLSVSTPVTQGGTVKVLTQGINTPPVLVHNQLVLTPSIVTTN---KKLADPVTLKIET--------------KVLQPANLGPTLTPHHPPALPSKLPAEVNHVPSGPSNPADRTIAHLATTKPDTHSPRPTGPTPGPFPRACHPSSTTSTALSTNATVMLAAGIPVPQFISSIHP-EQSVIMPPHSITQTVS-----LGHLSQGEVRMSTPTLPSITYSIRPETLHSPR--APLQPQQIEARAPQRVSTPQPATTAVPALATQHPPEEEVHYHLPVARAAAP---VQSEVLVMQSEYRLHPYTVPRDVRIMVHPHVTAVSEQPRATEGVVKVPPASKAPQQLVKEVVKTSDAKAVPAP--APVPVPVPVPTPAPPPHGEARILTVTPS-------------------------SQLQGLPLTPPVVVTHGVQIVHSSGELFQEYRYGDIRTYHAPAQ-LTHTQFPVASSINLPSRTKTSAQGPP-ESEPLQSTQPAQPAPSTQSTQPVPPAPPCQPSQLSQPAQPPSGKIPQVS------------------------------------QEAKGTQTGGIEQTRLPAMPTNRP-SEPHAQAQRAPGETPQPAHPSPVSVAMKPDLPTPLASQAAPKQPLFVPVNSGTSTPPGLALPHAEAQPAPK-----------------------------------------------------------------------------------------QDSAPHGTPQRPVDMVQLLKKYPIVWQGLLALKNDTAAVQLHFVSGNNVLAHRSLP--LSEGGPPLRIAQRMRLEASQLEGVARRMTVETDYCLLLALPCGRDQEDVVSQTESLKAAFITYLQAKQAAGIINVPNPGSNQPAYVLQIFPPCEFSESHLSRLAPDLLASISNISPHLMIVIASV", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q62504-1", "uniprot_id": "MINT_MOUSE", "id": "Q62504-1", "name": "Msx2-interacting protein", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MVRETRHLWVGNLPENVREEKIIEHFKRYGRVESVKILPKRGS-EGGVAAFVDFVDIKSAQKAHNSVNKMGDRDLRTDYNEP-----GTIPSAARG---LDETVSIASRSREVSGFRGSAGGPAYGPPPSLHAREGRYERRLDGASDNRERAYEHSAYGHHERGTG---AFDRTRHYDQDYYRDPRERTLQHG--------------------------------------------------LYYTSRSRSPNRFDAHDPRYEPRAREQFTLPSVVHRDIYRDDITREVRGRRPERSYQHSRSRSPHSSQSRNQSPQRLASQASRPTRSPSGSGSRSRSSSSDSISSSSSSSNTDSSDSSSTASDDSPARSVQSAAVPAPTSQLLS-SLEKDEPRKSFGIKVQNLPVRSIDTSLKDGLFHEFKKFGKVTSVQIHGASEERYGLVFFRQQEDQEKALTASKGKLFFGMQIEVTAWVGPETESENEFRPLDERIDEFHPKATRTLFIGNLEKTTTYHDLRNIFQRFGEIVDIDIKKVNGVPQYAFLQYCDIASVCKAIKKMDGEYLGNNRLKLGFGKSMPTNCVWLDGLSSNVSDQYLTRHFCRYGPVVKVVFDRLKGMALVLYSEIEDAQAAVKETKGRKIGGNKIKVDFANRESQLAFYHCMEKSGQDMRDFYEMLTERRAGQMAQSKHE----------------------------------------------------------------------------------------------DWSADAQSPHKCREERRGSY-EYSQE-----------------RTYYENVRTPGTYPE-------------------------------------------------------------------DSRRDYPARGRE-FYSEWETYQGEYYDSRYYDEPR---------------------------------EYREYRSDPYEQDIREYS--------------------------------------------------------------------------------------------YRQRERERERERFESDRD--HERRPIERSQSPVHLRRPQSPGVSPAHSERLPSDSERRLYRR-----------------------------------------------------------------SSERSGSCSSVSPPRYDKLEKARLERYTKNEKADKER-------------------------------------------------------------------------------------------------------------------------TFDPER---VERERRIVRKEKGEKDKAERQK---------------------------------------------------------------------------------------------------------------------------------------------------------------RKGKAHSPSSQPSETEQENDREQSPEKPRGST-KLSRDRA----DKEGPAKNRLELVPCVV-LTRVKEKEGKVIEHPPP--EKLKARLGRDTTKASALDQKPQAAQGEPAKSDP-----ARGKALREKVLPSHAEVGEKEGRTKLRKHLKAEQ-TPELSALDLEKLEARKRRFADSGLKIEKQKPEIKKTSPETEDTRILLKKQPDTS--RDGVLLREGESERKPVRKEILKRESKKTKLERLNSALSPKDCQDPAAVSAGSGSRPSSDVHAGLGELTHGSVETQE--TQPKKA--IPSKPQPKQLQLLENQGPEKEEVRKNYCRPREEPAEHRAGQEKPHGGNAEEKLGIDIDHTQSYRKQMEQSRRKQRMEMEIAKAEKFGS-PKKDVDDYERRSLVHEVGKPPQDVTDDSPPSKKRRTD----------------------------------HVDFDICTKRERNYRSSRQISEDSERTSCSPSVRHGSFHDDDDPRGSPRLVSVK---GSPKGDEKGLPYPNAAVRDDPLKCNPYDSGKREQTADTAKIKLSVLNSEGEPSRWDPPMKQD----PSRFDVSFPNSVIKRDSLRKRSVRDLEPGEVPSDSDEDAEHRSQSPRASSFYDSPRLSFLLRDRDQKLRERDERLASSLERNKFYSFALDKTITPDTKALLERAKSLSSSREENWSFLDWDSRFANFRNNKDKEKVDSAPRPIPSWYMKKKKIRTDSEGKLDDKKD-------------------ERREEEQERQELFASRFLHSSIFEQDSKRLQHLERKSEESDFPPGRLYGRQASEG------------------ANSTSDSVQEPVVLFHSRFMELT-RMQQKEKEKDQKPKEAEKQEEPETHPKTPEPAAE---------------------------------------------------------------------TKEPEPKAPVSAGLPAVTITVVTPEPASSAPEKAEEAAEAPSPAGEKPAEPAPVSEETKLVSEPVSVPVEQPRQSDVPPGEDSRDSQDSAALAPSAPQE-------SAATDAVPCVNAEPLTPGTTVSQVESSVDPKPSSPQPLSKLTQRSEE---------AEEGKVEKPDTTPSTEPDATQNAGVASEAQPPASEDVEANPPVAAKDRK----------TNKSKRSKTSVQAAAASVVEKPVTRKSERIDREKLKRSSSPRGEAQKLLELKM---------------EAEKITRTASKSSGGDTEHPEPSLPLSRSR-RRNVRSVYATMTDHES--------------------------RSPAKEPVEQPRVTRKRLER--ELQEAVVPPTTP------------------------------------------------------------------------------RRGRPPKTRRRAEEDGEHERKEPAETPRPAEGWRSPRSQKSAAAAGPQGKRGRNE-----------------------QKVEAAAEAGAQASTREGNPK-SRGEREAASEPKRDRRDPSTDKSGPDTFPVEVLERKPP-EKTYKSKRGRARSTRSGMDRAAHQRSLEMAAR---AAGQAADKEAGPAAASPQE--SESPQKGSGSSPQLANNPAD-PDREAEEESASASTAPPEGTQLARQIELEQAVQNIAKLPEPSAAAASKGTATA----------------------------------------------------------------------------------------------------TATAASEEPAPEHGHKPAHQASETELAAAIGSIISD-ASGEPENFSAPPSVPPGSQTHPR----------------------EGMEPG-----LHEAESGILETGTATESSAPQ--------------------------------------VSALDPPEGSADTKETRGNSGD---SVQEAKGSK-AEVTPPRKDKGRQKTTR-RRKRNANKKVVAITETRASEAEQTQSESPAAEEATAAT--------------------------------------------------------------------------------------------------------------------PEAPQEEKPSEKPPS-PPAECTFDPSKTPPAESLSQENSAAEKTPCKAPVLPALPPLSQPALMDDGPQARFKVHSIIESDPVTPP-------------------------------------------SDSGIPPPTIPLVTIAKLPPPVIPG-----GVPHQSPPPKVTEWITRQEEPRAQSTPS---------------------------PALPPDTKASDMDTSSSTLRKILMDPKYVSATG---VTSTSVTTAIAEPVS-APCLQEAPAPPCDPKHPPL-----EGVSAAAVPNADTQASEVPVAADKE----KVAPVIAPKITSVISRMPVSIDLENSQKITLAKPAPQTLTGLVSALTGLVNVSLVPVNALKGPVKGSVATLKGLVSTPAGPVNLLKGPVNVLTGPVNVLTTPVSATVGTVNAAPGPVTAAC------------------------------------------------GVTATTGTAAVTGAVTAPAAKGKQRASSNENSRFHPGSMSVIDDRPADTGSGAGLRVNTSEG------VVLLSYSGQKTEGPQRISAKISQIPPASAMDIEFQQSVSKSQVKADSITPTQS-----------------------------------------------APKGPQTPSAFANVAAHSTLVLTAQTYNAS-------------------------------------PVISSVKTDRPSLEKPEPIHLSVSTPVTQGGTVKVLTQGINTPPVLVHNQLVLTPSIVTTN---KKLADPVTLKIET--------------KVLQPANLGPTLTPHHPPALPSKLPAEVNHVPSGPSTPADRTIAHLATPKPDTHSPRPTGPTPGLFPRPCHPSSTTSTALSTNATVMLAAGIPVPQFISSIHP-EQSVIMPPHSITQTVS-----LGHLSQGEVRMSTPTLPSITYSIRPETLHSPR--APLQPQQIEARAPQRVGTPQPATTGVPALATQHPPEEEVHYHLPVARAAAP---VQSEVLVMQSEYRLHPYTVPRDVRIMVHPHVTAVSEQPRATEGVVKVPPANKAPQQLVKEAVKTSDAKAVPAP--APVPVPVPVPTPAPPPHGEARILTVTPS-------------------------SQLQGLPLTPPVVVTHGVQIVHSSGELFQEYRYGDVRTYHAPAQQLTHTQFPVASSISLASRTKTSAQVPP-EGEPLQSTQSAQPAPSTQATQPIPPAPPCQPSQLSQPAQPPSGKIPQVS------------------------------------QEAKGTQTGGVEQTRLPAIPTNRP-SEPHAQLQRAPVETAQPAHPSPVSVSMKPDLPSPLSSQAAPKQPLFVPANSGPSTPPGLALPHAEVQPAPK-----------------------------------------------------------------------------------------QESSPHGTPQRPVDMVQLLKKYPIVWQGLLALKNDTAAVQLHFVSGNNVLAHRSLP--LSEGGPPLRIAQRMRLEASQLEGVARRMTVETDYCLLLALPCGRDQEDVVSQTESLKAAFITYLQAKQAAGIINVPNPGSNQPAYVLQIFPPCEFSESHLSRLAPDLLASISNISPHLMIVIASV", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q96T58-1", "uniprot_id": "MINT_HUMAN", "id": "Q96T58-1", "name": "Msx2-interacting protein", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MVRETRHLWVGNLPENVREEKIIEHFKRYGRVESVKILPKRGS-EGGVAAFVDFVDIKSAQKAHNSVNKMGDRDLRTDYNEP-----GTIPSAARG---LDDTVSIASRSREVSGFRGGGGGPAYGPPPSLHAREGRYERRLDGASDNRERAYEHSAYGHHERGTG---GFDRTRHYDQDYYRDPRERTLQHG--------------------------------------------------LYYASRSRSPNRFDAHDPRYEPRAREQFTLPSVVHRDIYRDDITREVRGRRPERNYQHSRSRSPHSSQSRNQSPQRLASQASRPTRSPSGSGSRSRSSSSDSISSSSSTS-SDSSDSSSSSSDDSPARSVQSAAVPAPTSQLLS-SLEKDEPRKSFGIKVQNLPVRSTDTSLKDGLFHEFKKFGKVTSVQIHGTSEERYGLVFFRQQEDQEKALTASKGKLFFGMQIEVTAWIGPETESENEFRPLDERIDEFHPKATRTLFIGNLEKTTTYHDLRNIFQRFGEIVDIDIKKVNGVPQYAFLQYCDIASVCKAIKKMDGEYLGNNRLKLGFGKSMPTNCVWLDGLSSNVSDQYLTRHFCRYGPVVKVVFDRLKGMALVLYNEIEYAQAAVKETKGRKIGGNKIKVDFANRESQLAFYHCMEKSGQDIRDFYEMLAER---------------------------------------------------------------------------------------------------------------------REERRASY-DYNQD-----------------RTYYESVRTPGTYPE-------------------------------------------------------------------DSRRDYPARGRE-FYSEWETYQGDYYESRYYDDPR---------------------------------EYRDYRNDPYEQDIREYS--------------------------------------------------------------------------------------------YRQRERERERERFESDRDRDHERRPIERSQSPVHLRRPQSPGASPSQAERLPSDSERRLYSR-----------------------------------------------------------------SSDRSGSCSSLSPPRYEKLDKSRLERYTKNEKTDKER-------------------------------------------------------------------------------------------------------------------------TFDPER---VERERRLIRKEKVEKDKTDKQK---------------------------------------------------------------------------------------------------------------------------------------------------------------RKGKVHSPSSQSSETDQENEREQSPEKPRSCN-KLSREKA----DKEGIAKNRLELMPCVV-LTRVKEKEGKVIDHTPV--EKLKAKLDNDTVKSSALDQKLQVSQTEPAKSDLSKLESVRMKVPKEKGLSSHVEVVEKEGRLKARKHLKPEQPADGVSAVDLEKLEARKRRFADSNLKAEKQKPEVKKSSPEMEDARVLSKKQPDVSS-REVILLREGEAERKPVRKEILKRESKKIKLDRLNTVASPKDCQELASISVGSGSRPSSDLQARLGELAGESVENQE--VQSKKP--IPSKPQLKQLQVLDDQGPEREDVRKNYCSLRDETPERKSGQEKSHSVNTEEKIGIDIDHTQSYRKQMEQSRRKQQMEMEIAKSEKFGS-PKKDVDEYERRSLVHEVGKPPQDVTDDSPPSKKKRMD----------------------------------HVDFDICTKRERNYRSSRQISEDSERTGGSPSVRHGSFHEDEDPIGSPRLLSVK---GSPKVDEKVLPYSNITVREESLKFNPYDSSRREQMADMAKIKLSVLNSEDELNRWDSQMKQD----AGRFDVSFPNSIIKRDSLRKRSVRDLEPGEVPSDSDEDGEHKSHSPRASALYESSRLSFLLRDREDKLRERDERLSSSLERNKFYSFALDKTITPDTKALLERAKSLSSSREENWSFLDWDSRFANFRNNKDKEKVDSAPRPIPSWYMKKKKIRTDSEGKMDDKKE-------------------DHKEEEQERQELFASRFLHSSIFEQDSKRLQHLERKEEDSDFISGRIYGKQTSEG------------------ANSTTDSIQEPVVLFHSRFMELT-RMQQKEKEKDQKPKEVEKQEDTENHPKTPESAPE---------------------------------------------------------------------NKDSELKTPPSVGPPSVTVVTLESAPSALEKTTGDKTVEAPLVTEEKTVEPATVSEEAKPASEPAPAPVEQLEQVDLPPG---ADPDKEAAMMPAGVEE-------GSSGDQPPYLDAKPPTPGASFSQAESNVDPEPDSTQPLSKPAQKSEE---------ANEPKAEKPDATADAEPDANQKAEAAPESQPPASEDLEVDPPVAAKDKK----------PNKSKRSKTPVQAAAVSIVEKPVTRKSERIDREKLKRSNSPRGEAQKLLELKM---------------EAEKITRTASKNSAADLEHPEPSLPLSRTR-RRNVRSVYATMGDHEN--------------------------RSPVKEPVEQPRVTRKRLER--ELQEAAAVPTTP------------------------------------------------------------------------------RRGRPPKTRRRADEEEENEAKEPAETLKPPEGWRSPRSQKTAAGGGPQGKKGKNEPKVDA------------------TRPEATTEVGPQIGVKESSMEPKAAEEEAGSEQKRDRKDAGTDKNPPETAPVEVVEKKPAPEKNSKSKRGRSRNSRLAVDKSASLKNVDAAVSPRGAAAQAGERESGVVAVSPEK--SESPQKEDGLSSQLKSDPVD-PDKEPEKEDVSASGPSPEATQLAKQMELEQAVEHIAKLAEASASAAYKADA-----------------------------------------------------------------------------------------------------------PEGLAPEDRDKPAHQASETELAAAIGSIIND-ISGEPENFPAPPPYPGESQTDLQPPAG-----------------AQALQPSEEGMETDEAVSGILETEAATESSRPP--------------------------------------VNAPDPSAGPTDTKEARGNSSETSHSVPEAKGSKEVEVTLVRKDKGRQKTTRSRRKRNTNKKVVAPVESHVPESNQAQGESPAANEGTTVQH-------------------------------------------------------------------------------------------------------------------PEAPQEEKQSEKPHSTPPQSCTSDLSKIPSTENSSQEISVEERTPTKASVPPDLPPPPQPAPVDEEPQARFRVHSIIESDPVTPP-------------------------------------------SDPSIPIPTLPSVTAAKLSPPVASG-----GIPHQSPPTKVTEWITRQEEPRAQSTPS---------------------------PALPPDTKASDVDTSSSTLRKILMDPKYVSATS---VTSTSVTTAIAEPVSAAPCLHEAPPPPVDSKKPLE-----EKTAPPVTNNSEIQASEVLVAADKE----KVAPVIAPKITSVISRMPVSIDLENSQKITLAKPAPQTLTGLVSALTGLVNVSLVPVNALKGPVKGSVTTLKSLVSTPAGPVNVLKGPVNVLTGPVNVLTTPVNATVGTVNAAPGTVNAAASAVNATASAVTVTAGAVTAASG--------------------------GVTATTGTVTMAGAVIAPSTKCKQRASANENSRFHPGSMPVIDDRPADAGSGAGLRVNTSEG------VVLLSYSGQKTEGPQRISAKISQIPPASAMDIEFQQSVSKSQVKPDSVTASQP-----------------------------------------------PSKGPQAPAGYANVATHSTLVLTAQTYNAS-------------------------------------PVISSVKADRPSLEKPEPIHLSVSTPVTQGGTVKVLTQGINTPPVLVHNQLVLTPSIVTTN---KKLADPVTLKIET--------------KVLQPANLGSTLTPHHPPALPSKLPTEVNHVPSGPSIPADRTVSHLAAAKLDAHSPRPSGPGPSSFPRASHPSSTASTALSTNATVMLAAGIPVPQFISSIHP-EQSVIMPPHSITQTVS-----LSHLSQGEVRMNTPTLPSITYSIRPEALHSPR--APLQPQQIEVRAPQRASTPQPAPAGVPALASQHPPEEEVHYHLPVARATAP---VQSEVLVMQSEYRLHPYTVPRDVRIMVHPHVTAVSEQPRAADGVVKVPPASKAPQQPGKEAAKTPDAKAAPTPTPAPVPVPVPLPAPAPAPHGEARILTVTPS-------------------------NQLQGLPLTPPVVVTHGVQIVHSSGELFQEYRYGDIRTYHPPAQ-LTHTQFPAASSVGLPSRTKTAAQGPPPEGEPLQ------PPQPVQSTQPAQPAPPCPPSQLGQPGQPPSSKMPQVS------------------------------------QEAKGTQTG-VEQPRLPAGPANRP-PEPHTQVQRAQAETGPTSFPSPVSVSMKPDLPVSLPTQTAPKQPLFVPTTSGPSTPPGLVLPHTEFQPAPK-----------------------------------------------------------------------------------------QDSSPHLTSQRPVDMVQLLKKYPIVWQGLLALKNDTAAVQLHFVSGNNVLAHRSLP--LSEGGPPLRIAQRMRLEATQLEGVARRMTVETDYCLLLALPCGRDQEDVVSQTESLKAAFITYLQAKQAAGIINVPNPGSNQPAYVLQIFPPCEFSESHLSRLAPDLLASISNISPHLMIVIASV", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F1QMN6-1", "uniprot_id": "F1QMN6_DANRE", "id": "F1QMN6-1", "name": "Msx2-interacting protein", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MVRETRHLWVGNLPENVREEKIIEHFKRYGRVESVKVLPKRGS-EGGVAAFVDFVDIKSAQKAHNSINKMGDRDLRTDYNEP-----GTIPSAARG---LDDSLSIATRGRDVSGFTRGAGGPVYGPSVSLHSREGRFERRLDGTSDSRERSYDHSAYGHHERSSSNSTSFDRQRHYESDYYRDSRDRALSGTSGSASSASGSIGGSSSAGSIGVAGNVAGSSGAGGSTAAGVGSGGSTPGGIVYYGSRSRSPSRFETTETRYEPRAREAFTLASVVHRDLFR-----EERGRRGERTYHHSRSRSPHSSQSHNPSPQRLQSQAARPARSRSGSGSRSRSSSSDSVSSTSSSG-SGSSDSSSTSSDRSPARSVQSTAVPAPSTQPLP-SLDKDEPRKSFGIKVQNLPVRSTDTSLKDGLFHEFKKHGKVTSVQIHGASEERYGLVFFRQQEDQEKALSASKGKLFFGMQIDVTAWHGPETESENEFRPLDERIDEFHPKATRTLFIGNLEKTTTYNDLLNIFQRFGEIVDIDIKKVNGSPQYAFLQYCDIASVCKAIKKMDGEYLGNNRLKLGFGKSMPTTCVWLDGLSSSITEQYLTRHFCRYGHVVKVVFDRLKGMALILYNNIEYAQAAVKETKGWKIGGNKIKVDFANQESQMAFYRSMQGSGQDIRDFYEIISER---------------------------------------------------------------------------------------------------------------------RDERRTPYHEFTAE-----------------RAYYENVRTPTSYTE-------------------------------------------------------------------DPRRKYPARSRE-FFSEWDPYQGDYYDPRYYDDSR---------------------------------EYRDFR-DPYEQDIRKYS--------------------------------------------------------------------------------------------YLQRERERERERFETDRERDHGRRTIEHQQSPTHSRRPASPTASPSLSERPPSDSEHHVYSR-----------------------------------------------------------------SSERSGSCSSLSPPRFEKPDKIRLERHNRNDKLEKEKS------------------------------------------------------------------------------------------------------------------------LFETERGNGGEKERRAGRKEKGEKDRTERQKL--------------------------------------------------------------------------------------------------------------------------------------------------------------KKLKLASPTVPSPEAELELDRDASPEANITLRGKVSKSLIK---DKDYSGKGKLDLLPCVVQLTRVKEKEGKLIDSILC--EKQKTKVGSDPVLSPTTPSSGDHKSMPFRKDTQARDFFKHGKHLKEKGLASQVEVVDKEEKVKNKKYFKSDLAFESSSSVDADRKAARKRRFEETSAKADN----LRRVSQEEDEG--KLRRIIDEP------LLKDTDYDKKLLRKEAHKRE-RKIKPERMVTVSTTIEELDNVMPVG-----PSLDLQARLGEPAEDAIDPLD--SLDQKIGAFGANRQPSFSLAVSDDGSVDMDFSREQEQ-QHLTSYHTLSSRQERVSESKESLLSDIDHSQSCRKQMEQNRRLQQQMLECDKSDKTESTPSTDAEEFEHRSIVHEVVKPLQDVTGSSPTSKQKKLG----------------------------------GFEFDFG-KREQNYEMFRLRNDEPERGLAS---HPGTPLAEEERNASQLLDKDP---DLPVTMDKNSSHLDVSKYN---TSNAVHQG-LSPHAEILKVKPSVTKEEFS---WESNIRQG----TLR-EMSFPTSIVKRESIRKRPERELEPGEVQSDSDED-ESRHYSLKPISFK-----------REHEERLSDVKYSESLEKNKFYEFALDKTITPDTKALLERAKSLSSSREENWFFLNHDSKFKSLQNNIDKEKSEPTPRPIPSWYLKKKKSRSDSDGKLDEKKQ-------------------DAKPDEQERQDLLASRFLHSSIFEQDSRRLQHLERKNTDPDVRIGRDSVTSNSQGEQP---------------GTGGSDLTQEPRVLFHSRFLELQQRDKNQQLPISEKLSLTDQMEKTLDEEFRPSPNLS---------------------------------------------------------------------DISQESLASHSLTP---TISPVSQSKISEMSVHHEKPVLHTTLPNIHNPAVVNVRSENAPIDYPSLISLKD-ENNTIPLSTPSPEPMIKEDVIVEEPEEKLRDSRKTVHAAVEHEIEIKPPTPGASLGNVEPECDALQASSPLYPNPSKDQET---------TELSET-------TTEPANSSLVVSPLEVPDTEIEQVEQVLPP-RKQPK----------SKKVKNVSSAQTPITQVVNEKPATRKSERIDKEKLKRS--PRGDSTKLTADSR---------------NSAKSPVQVLDSEQG----LELNTNQGRTRQRRNVRSVYATPPEEESP-------------------------QQQGKEVTEPPRSTLKRSRGRPPKTRRRVDDMSP------------------------------------------------------------------------------VKGDQIKNSE-AEDTENKESTSSGEITKSTEAWRSPRSQKGQSSPIRSGQSKKTLKLDKVSGTSACVQL-------DREAVDVPPALDRKAESKETLMQVGHLSKDTKQNSISTREKELVAEEISTDDRVEITPVEKILDKEVKTSRSTRNTKTMSDNKAVNVVKLTMDAVKEAVHSGDDITVCFEGSLKANV--PQSVIEQSDIQDYHKKENVNSLDEKDETLSEMEPPTDPVAALLARQMELERAVENISRFTDDQHPVPYKEPRTEPP------------------------------------------------------------------------------------------------TLTAPVVVQPAEDTEVGKPANPASETELAEAINSITAEDISGDTDGFSASTTYTT-------------------------------LLPQ-----PETLDLPVPNEVVETESDLTV--------------------------------------KTIAQSEQDNVMVPVSKSSKCKTDTSLKES------PLTEVAKRGGRARPKTAKKSR--GRKVSLNRKLDIAEDVVLEPESTTVKL-------------------------------------------------------------------------------------------------------------------------PESIPEEIQTVNPKA-----ATSAAAAAVVTVAAACKHEAASTVILNTPKEAEQPAVDQPEPQESAFHSGNNSPSYLRTQQSSPER------------------------------------------GASALTSPTTRLNSPASSNIPPEWN-----TRTEEKVMLPKPQGNVALSIPGAGGPPAN--------------------------PPMPPDTKASDINASSSTLRKILMEPKYVSASNSNSVTSMQFTTTLADPRMSDNENSVEAVLPLKTSLPED-----RPSPIAQLVPRTTPPQPPPLQQCETPQILKEKLAITSTATSVISRIPMPFDFEDTPRISLSN------------------------------RNSGMSLPKQKYRTGLNENNRYHG---------------------------------------------------------------------------------------------------------HNTSEDGGSVGRP----VVEGTHCNTGSSTGLRVNTSEG------VVVLSYSGQKTEGPQRIIAKISQIPPASAVDIEFQQSITKSQIKQE-PSSHPS-----------------------------------------------TPKGSQTPTGYS----HTGVVLAGQSINAQ-------------------------------------PVISSIRQESPGSEKSE-------TSYQQGSSLKSFHQSPSHPQLLRYGQSITPQHHMKKNGETESFSMKADIKPDI--------------KATQTFNVKPVLSPRHPSFSG-------NHILS-PSAPHERAVP---QPKQDSHSPRASNHSMSPFPKVCPP----------NSPVVLGPAGPMSQYVSNIHHAEQSVIMPPHSVTQSVP-----MSHLSQGDVRASTPTLSGIGYGLRSENLLSPRSAPPQRSTTPQPAVIRDVILKSHAGSSVGGHVVETSNDDAQNLPQGLRRSSAPQ--LQQESMVIQSEFKNLHHRALR-----LDQYARLMQQHLTDHPGVVESRQTRTAEVVQSSSHISSASSKASSIVKNAPQIVRDGQKTVELKMS-----PSPHSD-------------------------NRITGHPPGSVMVSPQGVQLNYPGNGNTMNEYYKEMRGFH--------PQYPGHSVIGIN----LANRGIP-------------------------------VSQVSQIDHSQRHKVPSLS------------------------------------SSES---VGSFSESKLEGSHIRHSGTMDLSHISRVQSEAGSPSYISPVTITPKLELAITLQKGPQG------PVSNKMPLPS---LASSQMRSDFK-----------------------------------------------------------------------------------------LDH----TGLRSVDMVQLLTKYPIIWQGHLALKNDTAAVQLHFVSGNNVLAHRSLP--PPEGGAFLRIAQRMRLEASQLEGVARRMTAENEYCLLLALPCGLDQEDVHNQTHALKTGFITYLQAKQAAGIINVPNPGSNQPAYVVQIFPPCEFSESHLSHLAPDLLNSISSISPHLMIVIASV", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q8SX83-1", "uniprot_id": "SPEN_DROME", "id": "Q8SX83-1", "name": "Protein split ends", "aln": "MFRCRNMVRDNSRNICFGKLAETTTTQQQQQQQQFVVDSSTIINNNNNNNNNNNNQKLKRSTEEPPTNSFERNYYDRTTSRLVTQYQANNSTSLANSNSSPSSVSASASVFATAAGGSSERSRNRDRPYRNGSASVQGGGINSSNTTTTTAACTAGGSGSGAIGTGTGGLVGSGPGGVPQALGDRSSTQNIHQNHQSARVAPPQSWYEAATAATTAQLKSSGGSGNAGASAAVGFTMSSSPINHHPHQHPHLQNPQHPHYTSSPVVGAGSCPSAAQGQPQIQSQSQTTAVHRSVAYAGSAADDLLNTATSRNMLLHSSKLNKLLKGAGATGSGGERSGSESPGRAGGATPLTTTSTITNNSFSSNSLNNTITTATPTMPTIASGAAGSVGLGSGAEAG--------------------------VCSNSGTASGDILNVAAVLAAAVDNGVPTHPIRTRHNLHGRSTTSSSRSHSRSPSSYSSSHSSSSSSHSSSHSHASSPVQSSGNCAMAEGRSSRTVNSVTVTSNSSNPSGTAVTVSSAGVGGGCGSSSSSSSSSSSSGSSCLTANPVVHSEDNRPLAIRVRNLPARSSDTSLKDGLFHEYKKHGKVTWVKVVGQNSERYALVCFKKPDDVEKALEVSHDKHFFGCKIEVEPYQGYDVE-DNEFRPYEAELDEYHPKSTRTLFIGNLEKDITAGELRSHFEAFGEIIEIDIKKQ-GLNAYAFCQYSDIVSVVKAMRKMDGEHLGSNRIKLGFGKSMPTNCVWIDGVDEKVSESFLQSQFTRFGAVTKVSIDRNRQLALVLYDQVQNAQAAVKDMRGTILRRKKLQVDFASRECQDAFYDKQEKQQQQSSGSNPRFSRYESSASSLQSRSRASSFSRHQNNSNDDCSPINTPGGASSGISSASNLINQSTSINISNIGTNACSAMPAPSLASAVVSCNVNASGTVPASTSMPSGVSSSSSSLPMSPAALAQRHRMVRNARQTVDCDFNEVGRLRFRSSEEVSGGAGNSTQFEDVRCDSPVTARQGSAVNCFTGPTAAVGESIDGTLNNNQITGGAEGFTGSGGSILSRRRCGKTPKDLHPVHNQRIQLAEQVEECPSSGDEGVVSPRKRIKMDYHHHHHHSNASGVESTGEHSSINKPSPLLLSNCDVIHDPLNRKSEIRRVSETPSGSPSIKFPGHLPSAPQSLMLSCRRPSIDVGALSALSSSSAFRHGIVGASSMDQQHMMNASAAAKRRRVTTTMQQPSSSSTTNSSSGSGLGGISSLTPADEYHHHVSRGRGHQLHSHHSHEASGGESADGSRPGTPLCDERPEVLPTEPRRLPPPRERVRERTRDVMWLPLPKFGVLFFQQQQSRSSGGGGAGNSYLQQQLGGGSTGGLGCIGAASSSACSLNNSSLNASQGMGSCSGSTFLPSPSSRYWRSSSHHQNQQNNHQQQSQQLHGSSSSNTCLMASPARPRSLSSNSSDSDVPGQNAGGSPSLDERLRNFEENYERWSGGSSREHISGHTPSSATPSWQLSMHMNLSTGLNSHQTSSASGNSNSSSGTVSSSASNSRHKFLDIDELQPSDIVKSVLAKKSVFDDDFQRLNKNQWYDPSSSDFALGSSSNIVTGSSLVANVSRHPGGPCSGNTSPALPNLAATKATPIIGNCSGGLGNSTGSKSAGLLQRLSSLSPMNSPQASMSPYNSPSPSPSVGGVTACLGQLTKPAAPGTASAGLSGGTAASSSSPAANSGPTKGLQYPFPSHPPLPNTAAPPPAVQPAPPPLPEMGKQSRLTGQSSGNNLTKSLSVPDGPQSSPARVQLQKSASVPGSTNVGAPSSLSLDSTTASVETSASISSSTSNGNSSLTSAAIHVQKPQQSTFVEEEHTKKSGTSTSQSSSSSSKKISSTHDKLHSKHNNRSESDKKIKKSDKNASSSDKRKNSSTSQSSKSATPRIEDDSSEADDTADKAEKNQRHEKEKKERQEKREKDLRKQVEREEKDRKAQQEEREKEDRKAKEEEKEREREKKAQEDREKKEREERELREKEQRDKEQKEKEIREKDLREKEQRERDNREKELRDKDLREKEMREKEQREKELHREKDQREREHREKEQSRRAMDVEQEGRGGRMRELSSYQKSKMDIAGEASSLTAIDCQHNKENAMDTIAQGTPGASPSTPSDNTPKERSRKLSRNSPVRLHKRRLSSQESNHSAGGGGSCGGSSHQIHHEDYVKRIRMENSQNISVHSSNQRLNDRRDSKEHKSSSFKEDKNSSSHISRPHGCGGSSASSSKHHHRRDKHHQKGSASSIETNSSIEVVVDPISQTKHNLNTSEEELQSHQPKREKEREHFSSHANSSSSRHKSKRDHHHHREKKRHSVAESTNTDEEHTPQQHNPHRRISAAGSGSAGELSSAATNTSSGKLHHQHHRRSVERKSSRGSDEGHHSSSKSLRAKLMMLSSADSDDTDDASKKHSIFDIPDDCPNVSMYDKVKARSCKNMQRQAEEKKIKAKFSQLKQSRAKKKRSTSYDGDSDTEFEDRQHRNSGSSSFHGRYPGLSSSDDDDDEETHQRRISSDSDAEHGGQDNQGASTLADANRVRQMQQNLRRLCDGDDSSEDEIRRNVMKHSHFGKRNSNSTRIASDSESQSQPAPDLTIKQEHPIAPAQEIKREQLSDEEQKFKSRHDSNSSIEERKLKTEREIKTELGDFYNSSEYTYTGKLKEYSPETRKKHKKSKRRLKSSSTADTSAAQTPLVMTPLTPSIFDVHSSSECKTKFDNFDDLKTECSSIPLEISAGERRKHKERKEKKREKLRNMTEATVPNSPTTNDTSSEKLSKEERHRLKKSKKSKSMDNSCNTKIYNSSGAHPSTSPSLPATPTSAPSTAQTSKRGEDKMEFIFGIISDEEESQFPEQAETNKDIIPSSVSTTGPIVSAALQTYKQEPSTPNSKNEEAHIQLTVHEPEQQQQLERSRLSGGSSSSSHADRERHRREKREKKRREKSQREQQNQIHQKSSKVETKVDDDNSVDMDEAGRALEAQLMSDFDTKPISEEATPSTAATYRSDMTDVFRFSDNEDNNSVDMTKQGVKSEQQEQHKSKDKKKKKKRSKEEKQEKLLQQQRRESLPNVASTSSAPPTPGKLTVNVQAASKHADLQLDAKHISSPPVCKPSPSLPCLIGDDDDDALHTPKAKPTTPSSRGNDGLTPSREKPRLISPIPKTPTIANSSTLSTQSAETPVSSGTVISSSALATTPTSSTAAGVSAAPGLDNSPTSASAQCKKKESFIPGFDGQLDDRISESAVQSISAEFNSTSLLDNIADEPKIPVASPPRATKPLDKLEESKSRVTISQEETESAVSALLGESFGTSSTTDYSLDGMDEMSSVNELETPTLVIAEPDEEAALAAKAIETAGEPASILEEPEMEPEREAEPDPDPEAEIESEPVVEVLDPEELNKAVQSLKHEDMMDIKADTPQSERDLQIDTDTEENPDEADSSGPSLKIDETVQSSSSPEKSISNNSPTPRETANIDIPNVESQPKLSNESTPQPSVITKLPFLDTPKTVPAGLPPSPVKIEPPTISKLQQPLVQPVQTVLPAPHSTGSGISANSVINLDLSNVISSCSNTSAASATASASASISFGSPTASQNAMPQASTPKQGPITPQQAIRTQSLIMQPPTISIPEQTPHFAVPQMVLSPQSHHPQQPGTYMVGIRAPSPHSPLHSPGRGVAQSRLVGQLSPVGRPMVSQPSPQQQVQQTQQQHALITSPQSSNISPLASPTTRVLSSSNSPTTSKVNSYQPRNQQVPQQPSPKSVAEVQTTPQLMTIPLQKMTPIQVPHHPTIISKVVTVQPQQATQSQVASSPPLGSLPPHKNVHLNAHQNQQQPQVIAKMTAHQHQQHMQQFMHQQMIQRQQHMQQQQLHGQSQQITSAPQHQMHQQHQAQQQQQHHNQQHLNQQLHAQQHPTQKQHQAQQQFNQQIQQHQSQQQHQVQQQNQAQQQHLSQQQHQSQQQLNQQHQAQQQQLQQIQKLQQMHGPQQQQKSPQGVGHLGGSTSIFASQQHNSQLPARGVPQQQHPQQLSHSSPCKPNTLVSVNQGVQPPAILTRVGSHSQPNQQQQLPHQQSSSGHPHQKQLSSPGANLPLQTPLNVIQNTPKIIVQQHIVAQNQVPPPQTQGNAIHYPQNQGKDSTPPGHVEPTPAMSAQKTSESVSVIRTPTPTTGLAVISANTVGSLLTEENLIKISQPKQDELIEQDSKEVDSDYWSAKEVNIDSVIKKLDTPLASKDAKRAVEMQAIAPAPIPNPQPGNQSMAQETALPTTSMSVNNSNDHDTEDETETRQLPPAKPPIPTVGRPPGRGGSAKRGRQPRGAKKVGGFPLNSVTAAPPGVDSLVVQPGDNGVQTRLRKPVTAPVTRGRKGRPPRNLLLQQQQLQQQQLDIQRKGMEMVTSATSSTPLPTPIPTSSVLTAAEKKARNQALTQAQEQNQVASQVGTGQDIYEFHEDGGEEPKPKTISSVAPSAEDQRPRLILTINKTQPSIKNISEMEQTIQQQQQQQSEVISNTDPIGGDNSESCNTRKSRRLQEKEDRSTVDDIIEDVVRNTNTPTGTGPHLPKGAQTPPRRSGRNAQAKKTDAVQIINAVGRPRRSKDRKTIGEQTANLIEEVTASNATVAASHLAPPEGAGVESHVPQLDAKEVEPVSVVTPISTPAPVSVAAPVTVPVPAMVPVKPTMPQHPKKKAIAAAEIESYQAINSSIPSGGLPMHQTAAPATQKITGGVADAVSKALVDPVTGVITAGMPQGKEGNLPAATAAAPANSSNEDGQAAPPPQLQHQQQQQHPQQPPQQQANLQINTTLIPSGLPNPITALGKSVQLETSAAALLNKPVSVLVKGNASQVIQQQQPQIVAPAKQPIILQQNPLPTVLHHAQHTTVRPPQPLKAHVLNREKNIQQQLTPTKQAVAQPPQHAPHSGHMLLTDTAGNQQLVQPQIIARHLQQQQHLQVNVPPPTAHSPHSPRIPSQQQQLGPGASISPQQQQPQTVVIKQAASAAQPQILHVVSSKASVVPQPQQQQLPPTSSTGPHLQLAKPNYSYAPTVLTPTLPAVQQQQQQHLYKQNNQQKGAQIQMPPHGIIMPTHPGMLLQQKLPAHLQPQQHQLNPSPPPGKPNPVLHGLQSGQIMPGSVGSPPPVSAAVLKTAQQQVNSVVPVAGIRTAIPNISPQSQPRVSPLVLPPGISGVPPFDASLHDLGAYVSGRRTQSPPPAHQQASPITPNDSTYRGVTASRDFMLYQHHLMRGGDYDDKMGSSPPLELRRPGSGPPRTIAVPHSLQSPQDRTAADSPQMAQVYVHNTRIPPAHFSEIASRGLYDSGALQLEPPPAHRPTATISVVVPQQMPAVSSGSPFIGRDGSVQPGSHHHPGKAMDMQLDEMDRMSMIAAVVQQQQEHLPPALPAGMELASQQAPPAMAPPPGDSLVTLLQRYPVMWQGLLALKTDQAAVQMHFVHGNPNVARASLPSLVETNTPLLRIAQRMRLEQTQLEGVAKKMQVDKEHCMLLALPCGRDHADVLQHSRNLQTGFITYLQQKMAAGIVNIPIPGSEQAAYVVHIFPSCDFANENLERAAPDLKNRVAELA-HLLIVIATV", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . :. . . :.:: .. ** :.*.:* *.*. .*. : * : :. :..*... *: ****:* ::. . :: *.*: .... .. .. .:* :. . ::*. *. . :..: :. :.:: : * : * . ::. . . * . .::::. . *.: . . * *. **:* . * *:: .* .**: .* : : .*:..:. : : .*:. ... ..: * .*:: .: :: . .: :.* .:.:.*:*:***.** ***********:**.**** *:: * ..***.** *:: :* **** .*:.* *** :*:* .: * :.* :***** : .:**:***:*********** * :* . *: ****::***** * *** **.**.** **::*****:**.**:**********.***:**:...:::.:* :* *:* *.** :** : :**:**.::: *****:: :* : :*::****.:*.* *** : . *: . ::. *: *: ::. : :*.** . . : .. *: . * . * . : :*:. :::.:. * * * . ::. * :: . . .::.:.:. . * * . *: ..* *. *: :*: ****. : . * . : :*:: :::: :: :. : : *:. .* :: : : .*: .. . . * ::::. :. .: :*: ..* *.* .. :: *. : . . . . . : .: .* : .. *: : . . * : : **: .:. . .. :. * * :: .: : . :* :.:* .*: :: : :: . : . . * * : : :. . : . : ... :. .: :. : ..: : : .. :. :. * : .. : .: : :. . : :: . . :..:* .:.:: . : . * .* . ..: . . : .:: .* : . . .* : . ... : * .: ..* . :. .: . : : * . **: ::* : . .* . .:*. : . : : . : . :: . . *: ..:*:* : ***: .:: . : .: :: : . :. .. :::: ... ..*:.: *: : : ..:. .. : .*: * ::*. . * .* . :.* * * . . :: . *: **:* : . . ..: . . . * . . :. : * : : .: . . . * : : ... : ..... . *. .: :: * :: : : . . . : : . .. : . : :. . . . .:. .: .* .:** :*. * : :: . :: : .. * : * :: .*: :.:. :. ** : :* . :* : . . . ... .. :* *.. . * .. : . : . . . . :. :. : . . . .. . : .: . * : . : : : * .:.:: : :: : .: . . .*: . : :*: .*.* :. . . .*. . : * . : : .:* . . :: . . . * . . .. . : .::* . : : : :: : : : . : .. . : . * :. . . . : . .. *. * ..:. : ..*. :** . .: ... * * :*..: . . . :.:: . . . . . : . : . :* :: .: :: . *. .: : . . * :: . : .:.*:. .: .:* .: * : . : *: .*.: *: *::*:: :.* : . . .**.*:*. : :: . : * ** * :.:. . * : * *. ..:. : : . .. .: :: . . . .: .:: : . . : . : . :* . : * .: : . *:. ..:: .:. : :.:: * : : .* :: : : . . * .: . . : . . . : . . : . . : ::. :* : :. : : : .:: *. . .. .:...: . * .: : .:*: : . : .:: : . * .: . . * .* . * :* .. . . : * : . * .. .* ::: .* . . *. :. . : : .:* ** :**::*** ****.* ****:*** ** :*: *** . . ********** :******::* .:.::*:******* *: ** .::. *::.****** * ****:*:* ***:*.***::***.*:*::.:*.: **** ::.:: **:****:*", "identical_positions": 441, "similar_positions": 1031, "identity": "7.89%" }, { "cls_id": "homologset.agr.MGI:1891708", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9WVA9-1", "uniprot_id": "NPFF_RAT", "id": "Q9WVA9-1", "name": "Pro-FMRFamide-related neuropeptide FF", "aln": "MDS-KWAAVLLLLLLLRNWG--HAEEAGSWGEDQVFAEEDKGPHPSQYAHTPDRI-----QTPGSLMRVLLQAMERPRRNPAFLFQPQRFGRNAWGPWS-KEQLSPQA-----REFWSLAAPQRFGKK", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9WVA8-1", "uniprot_id": "NPFF_MOUSE", "id": "Q9WVA8-1", "name": "Pro-FMRFamide-related neuropeptide FF", "aln": "MDS-KWAALLLLLLLLLNWG--HTEEAGSWGEDQVFAGEDKGPHPPQYAHIPDRI-----QTPGSLFRVLLQAMDTPRRSPAFLFQPQRFGRSAWGSWS-KEQLNPQA-----RQFWSLAAPQRFGKK", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O15130-1", "uniprot_id": "NPFF_HUMAN", "id": "O15130-1", "name": "Pro-FMRFamide-related neuropeptide FF", "aln": "MDS-RQAAALLVLLLLIDGG--CAEGPGGQQEDQLSAEEDSEPLPPQDA-----------QTSGSLLHYLLQAMERPGRSQAFLFQPQRFGRNTQGSWR-NEWLSPRAGEGLNSQFWSLAAPQRFGKK", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AB32U370-1", "uniprot_id": "A0AB32U370_DANRE", "id": "A0AB32U370-1", "name": "", "aln": "MDAGVWFMLVGVLLVMADQSRSITQDEALEQNKRLLEEDEEQDHMLERPGAAQMNGLLEDRLLVEMLRSLLHGSQRYERNPSVLHQPQRFGRGARSGLSTEERIQSRDWETVPGQIWSMAVPQRFGKK", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "**: : :**:: : . :: . :.:: ::. : . : .::: **:. : *. :.*.*******.: . :* :..: ::**:*.*******", "identical_positions": 26, "similar_positions": 43, "identity": "20.31%" }, { "cls_id": "homologset.agr.MGI:1891713", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9V426-1", "uniprot_id": "Q9V426_DROME", "id": "Q9V426-1", "name": "", "aln": "MDSAGKNRYELLFMDDDVSDPLDNLVAPTAAAAAAAAGKKKQPSAAAAAATKTTANKVANSNNKANAGSNIGGP-------NAKKPNQAEKENKPNNALNKTDGKKFTPSADNKQQQFNNNASSNYKQQGAPRQGGGANRTREFGSGQGQGQGQGGQQQRSVNFRQQNGNAETREQRNNRRNVRENVGAPDGQQSRPYRGPGGGPGAGGDRPQRQNRNYDGQNRKREFDRQSGSDRTGVKSIDKRDGAGSHNWGSVKEAIDDVNKNESETNVTNAEG--GAKADESGTEPQNEQATAEEEAKELTLDEWKAQQGQ-RIKPTFNIRKAGEGE-DTTQWKKMVVLTSNKKKENDSEEELEYDPALYPQRVGRQQRVLDIQFNFNDGRRGGPGGFGGRGGRGGPRPGGFGG-GPRSEGGNRDGGNR-EGGRDNREGGNRGPR-DGQQ-HNNEGGGSSAQNQRPPIDRRGPGNNQNNNQNSGPGPNKRFERQQNTAPKVNDERQFPTLA----", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VBX3-1", "uniprot_id": "Q9VBX3_DROME", "id": "Q9VBX3-1", "name": "", "aln": "MQLAEKHIVALMFPAIDVSTFTFVSGVKFYIMDNSGNNRYELLFMDDDDSSGLAQPQIAAVVAAPKKPEPAKAP-------KAPK-SKSEKENKPVVAARKAN----APVAKN----------------ASPVKGGKGPAGGDVGRPKNP-TANGANNQGRFNNNQRYGNKESNGEFGNELPQRQ-------FNNRDNRGP----------PRVRTGEKFG---KREFDRQSGSDRTGVKSIDKREGGGAHNWGSPKQDIEDLKTTGETS--PQAEK--EDSANEQSADP--AVAAEEDESKQMTLDEWKALRDQ-RAKPNYNLRKAGEGAADNAEWKKMIVLS--KKKESNSEDELEYDPSLYPQRVGRLQRIVDIQFNFNDGRKVGFR-KGPRPG-AGPREGGFRNDGPRGEGGYRNDGPRGEGGYRNDGPRGEGPRNEGPRGEGYRNDGPRGEGFRGPRFNNGPSNGYENRQDNNRFGEKR--RSAQKPLKVDDEAQFPTLC----", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "A1L1K8-1", "uniprot_id": "HABP4_RAT", "id": "A1L1K8-1", "name": "Intracellular hyaluronan-binding protein 4", "aln": "MKGALGSPVAAAGAAMQE-TFGCVVANRFHQLLDDESDPFDILREAEHRRQQQLQRKRRDEAAAASGAGHRGGRSPAVASGHRPGAAGRRESQKERKSLAVSSAQQPDSPGG-PQPPGQKRTPRRGEQQGWNDNRGTDVVLDRAERRSYREYRPYDTERQAESTAEKFTDEKPVDRFDRDRPLRGRGGPRGGLRNRGRGGPGN-----------RAFDSFDQRGKRDFERYGSSDK-ANRMEDSMGGCGVRTWGSGKD-TSDTEPPAPMEETSMMEECQGVLDEESASKVPELEVEEENQVQEMTLDEWKNLQEQTRPKPEFNIRKP-----ESTVPSKAVVIHKSRYRDDIVKDDYEDESHVFRKAANDITSQLEINF------------------------GNLPRPGRGARGSTRGGRGRIRRTEN--------------------------------------------------YGPRAEVVTQDVAPNPDDPEDFPALA----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9JKS5-1", "uniprot_id": "HABP4_MOUSE", "id": "Q9JKS5-1", "name": "Intracellular hyaluronan-binding protein 4", "aln": "MKGALGSPVAAAGAAMQE-TFGCVVANRFHQLLDDESDPFDILREAEHRRQQQLQRKRRDEAAAASGAGHRGGRSPAVASGHRPGAGGRRESQKERKSLAASGAQQPDSPGG-PQPPGQKRTPRRGEQQGWNDNRGTDVVLERAERRSYREYRPYETERQADLPVEKFTDEKPVDRFDRDRPLRGRGGPRGGLRSRGRGGPGN-----------RAFDSFDQRGKRDFERYSSNDK-TNRMEDSMGGCGIRPWGSGKD-TSDTEPPAPMEETSMMEECQGTLDEESAAKVPELEVEEENQVQEMTLDEWKNLQEQTRPKPEFNIRKP-----ESTVPSKAVVIHKSRYRDDMVKEDYEDESHVFRKAANDITSQLEINF------------------------GNLPRPGRGARGSTRGGRGRMRRTEN--------------------------------------------------YGPRAEVVTQDVAPNPDDPEDFPALA----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q5JVS0-1", "uniprot_id": "HABP4_HUMAN", "id": "Q5JVS0-1", "name": "Intracellular hyaluronan-binding protein 4", "aln": "MKGALGSPVAAAGAAMQE-SFGCVVANRFHQLLDDESDPFDILREAERRRQQQLQRKRRDEAAAAAGAGPRGGRSPAGASGHRAGAGGRRESQKERKSLPAPVAQRPDSPGGGLQAPGQKRTPRRGEQQGWNDSRGPEGMLERAERRSYREYRPYETERQADFTAEKFPDEKPGDRFDRDRPLRGRGGPRGGMRGRGRGGPGN-----------RVFDAFDQRGKREFERYGGNDKIAVRTEDNMGGCGVRTWGSGKD-TSDVEPTAPMEEPTVVEESQGTPEEESPAKVPELEVEEETQVQEMTLDEWKNLQEQTRPKPEFNIRKP-----ESTVPSKAVVIHKSKYRDDMVKDDYEDDSHVFRKPANDITSQLEINF------------------------GNLPRPGRGARGGTRGGRGRIRRAEN--------------------------------------------------YGPRAEVVMQDVAPNPDDPEDFPALS----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q5XJA5-1", "uniprot_id": "HABP4_DANRE", "id": "Q5XJA5-1", "name": "Intracellular hyaluronan-binding protein 4", "aln": "MK-------ELVEEMPDE-GYGCTVANRFGQLLGDESDPFDILYAAGTEKKQ---KKKKEEPKKTS----------------TTTKSVKKESQRDRKTILP-------AGGG-----GQVRP-------------GHEVVEEPIQRRVTFDRKFNDAEK----PPLSFSVERPVDVLDR--PARGRGTGRG----KGARGPGFP----------RSNDGFDQRGKREFERHSGSDRSSVRSEEKRSGSGSRNWGSVRDHMSVIEVASPSEEVTENEETQEAVETDGENRPSETEEVIEV-AMEMTLDEWKALQEQSRPKVELNIRKT-----ESSVPSKAVVIHKSKLLQ---KQDGMDEDVVFRRPANDITCQLEFNF------------------------GSLDRPTRGGRGG-RGGRG--RGGPS--------------------------------------------------MPTLRSPQKFDSAPNPDDPEDFPALA----", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VXX1-1", "uniprot_id": "Q9VXX1_DROME", "id": "Q9VXX1-1", "name": "", "aln": "------------------------MNVPLVALTKDPKMKKSQKKSSMVAVPKMSQKPQK-----------------------AARLFQPKVENKIT-------------------------------------------LTTPLTAPKKERVKDIKVADPLEKEVESVFVTVPKNKLCKTRRNRP--------------------------------------GDRLFDRRSGSKRTGVKAVEKRNGAGAHNWGSIQQEIDLRQR----TNLRTFEG-----MKLPKVSSFVYEYDSSEETEQYTLDEWRAMQAQKKQVLNKFIMSDFGTKKEVTGGSEETVRAEGSGDTDDTKGLDKTGGTEQTGNTETGERSAGSGETETAAASG-------------VPDASGGSGGTEGSGGLGGSGELEDDGEE--------------------------------------------------LTADRPLYVVDILLNFNTDQGVIPYRLKFI", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . . .:: . . * .* *:* ....: : :. * * : *** :: . : * . : *****: : * : : . : : .: * : . .. . *. .. : : : . . ", "identical_positions": 18, "similar_positions": 46, "identity": "3.54%" }, { "cls_id": "homologset.agr.MGI:1891716", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9R0H2-1", "uniprot_id": "MUCEN_MOUSE", "id": "Q9R0H2-1", "name": "Endomucin", "aln": "MRLLQATVLFFLLSNSLCHSEDGKDVQNDSIPTPAETSTTKASVTIPGIVS-VTNPNKPADGTPPEGTTKSDVSQTSLVTTINSLTTPKHEVGTTTEGPLRNESSTMKITVPNTPTSNANSTLPGSQNKTENQSSIRTTEISVTTQLLD-ALPKITATSSASLTTAHTMS--LLQDTEDRKIATTPSTTPSYSSIILPVVIALVVITLLVFTLVGLYRICWKRDPGTPENGNDQPQSDKESVKLLTVKTISHESGEHSAQGKTKN", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6AY82-1", "uniprot_id": "MUCEN_RAT", "id": "Q6AY82-1", "name": "Endomucin", "aln": "MRLLQVTALFFLLSNSLCRGENSK--------ALTETSTTKASATTPDMVS-ITN--KSTGGTPPKGTTNSATPKTPLMPALDSPTTPKHET--TTRGVIKNEVSTIKTTVANPTISNAVSTLSSPQNKTENQSSIRTTEISGTNQLPDDQKPKTTETPSASLTTAKTIS--QIQDTEDGKITATTSTTPSYSSVILPVVIALIVITVLVFTLVGLYRICWKRDPGTPESGNDQPQSDKESVKLLTVKTISHESGEHSAQGKAKN", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9ULC0-1", "uniprot_id": "MUCEN_HUMAN", "id": "Q9ULC0-1", "name": "Endomucin", "aln": "MELLQVTILFLLPS--ICSSNSTGVLEAAN--NSLVVTTTKPSITTPNTESLQKNVVTPTTGTTPKGTITNELLKMSLMSTATFLTSKDEGLKATTTDVRKNDSIISNVTVTSVTLPNAVSTLQSSKPKTETQSSIKTTEIPGSVLQPDASPSKTGTLTSIPVTIPENTSQSQVIGTEGGKNASTSATSRSYSSIILPVVIALIVITLSVFVLVGLYRMCWKADPGTPENGNDQPQSDKESVKLLTVKTISHESGEHSAQGKTKN", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*.***.* **:* * :* .:. .:***.* * *. * .* ..: **.*:** .. : .*:.: *: .. ** . :*: : **.. . .** *** ..: ***.****:****. : * .* .* .:* ... * : .**. * ::*.:*: ****:********:***: **.******:*** ******.********************************:**", "identical_positions": 122, "similar_positions": 64, "identity": "46.04%" }, { "cls_id": "homologset.agr.MGI:1891717", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q6Y290-1", "uniprot_id": "GOLI_RAT", "id": "Q6Y290-1", "name": "E3 ubiquitin-protein ligase RNF130", "aln": "------------------MSGAARAGPARLAALALLTCSLWP-----TRADN----------ASQEYYTALINVTVQEPGRGTP-LTFRIDRGRYGLDSPKAEVRGQVLAPLPIHGVADHLGCDPQTR----FFVPPNIKQWIALLQRGNCTFKEKISRAAFHNAVAVVIYNNKSKEEPVTMTHPG-TGDIIAVMITELRGKDILSYLEKNISVQMTIAVGTRMP--PKNFSRGSLVFVSISFIVLMIISSAWLIFYFIQKIRYTNARDRNQRRLGDAAKKAISKLTTRTVKKGDKETDPDFDHCAVCIESYKQNDVVRVLPCKHVFHKSCVDPWLSEHCTCPMCKLNILKALGIVPNLPCTDNVAFDMERLTRTQAVNRRSALGDLANDSSLGLEPLRTSGISP-LPQDGELTPRTGEINIAVTKEWFIIASFGLLSALTLCYMIIRATASLNANEVEWF--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8VEM1-1", "uniprot_id": "GOLI_MOUSE", "id": "Q8VEM1-1", "name": "E3 ubiquitin-protein ligase RNF130", "aln": "------------------MSGAARAGPARLAALALLTCSLWP-----TRADN----------ASQEYYTALINVTVQEPGRGTP-LTFRIDRGRYGLDSPKAEVRGQVLAPLPIHGVADHLGCDPQTR----FFVPPNIKQWIALLQRGNCTFKEKISRAAFHNAVAVVIYNNKSKEEPVTMTHPG-TGDIIAVMITELRGKDILSYLEKNISVQMTIAVGTRMP--PKNFSRGSLVFVSISFIVLMIISSAWLIFYFIQKIRYTNARDRNQRRLGDAAKKAISKLTTRTVKKGDKETDPDFDHCAVCIESYKQNDVVRVLPCKHVFHKSCVDPWLSEHCTCPMCKLNILKALGIVPNLPCTDNVAFDMERLTRTQAVNRRAALGDLAGDSSLGLEPLRTSGISP-LPQDGELTPRTGEINIAVTKEWFIIASFGLLSALTLCYMIIRATASLNANEVEWF--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q86XS8-1", "uniprot_id": "GOLI_HUMAN", "id": "Q86XS8-1", "name": "E3 ubiquitin-protein ligase RNF130", "aln": "------------------MSCAGRAGPARLAALALLTCSLWP-----ARADN----------ASQEYYTALINVTVQEPGRGAP-LTFRIDRGRYGLDSPKAEVRGQVLAPLPLHGVADHLGCDPQTR----FFVPPNIKQWIALLQRGNCTFKEKISRAAFHNAVAVVIYNNKSKEEPVTMTHPG-TGDIIAVMITELRGKDILSYLEKNISVQMTIAVGTRMP--PKNFSRGSLVFVSISFIVLMIISSAWLIFYFIQKIRYTNARDRNQRRLGDAAKKAISKLTTRTVKKGDKETDPDFDHCAVCIESYKQNDVVRILPCKHVFHKSCVDPWLSEHCTCPMCKLNILKALGIVPNLPCTDNVAFDMERLTRTQAVNRRSALGDLAGDNSLGLEPLRTSGISP-LPQDGELTPRTGEINIAVTKEWFIIASFGLLSALTLCYMIIRATASLNANEVEWF--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1N5S3-1", "uniprot_id": "A0A8M1N5S3_DANRE", "id": "A0A8M1N5S3-1", "name": "E3 ubiquitin-protein ligase RNF130", "aln": "-----------------MLKRLAAPASCSSCLLALLLAFVSPRCSLSIGADKT-------MVNKEDYYSAIVNATVLDHKGNPQ-QMVTKNDGRYGQNSPKTEAKGIVVAPAAVNGAVDLQGCCPHTR----FIVPPKTTHWVAIMQRGKCTFKEKILKAAAFNASAVIIYNNNTKEDTVTMAHEG-TGDIVAVMITESFGKEILGFLEKNQTVLVSVIVGSRGM--PKNINRGSLVFVSISFIVLMIISSAWLIFYFIQKIRDTSARDRSQRRLGDAAKKAISKLTTRTVKRGDKETEPDFNHCAVCIEGYQLNDVVRILPCKHVFHKMCVDPWLNEHCTCPMCKLNILKALGVMPNLPCVDNMAFDMDRMSRSQTSSQRTALVDLSSETSISLEPLRHSSSSQ-LPSDEELIPRSGEINIAVTTGHFFNRNSVSPRSVVCEMELPDIQASLDMYDDNKS--", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q06003-1", "uniprot_id": "GOLI_DROME", "id": "Q06003-1", "name": "E3 ubiquitin-protein ligase goliath", "aln": "MYIRKTLLLACLVLLFGGLPPLTFPATTTTLVAAMSIANQDLERYFRPGNGTHSFSGMEDRIAVDVYNYAFLNWSYVEHGNMLCNMEFAQEQARYG-EGKVLNVTGRLIHITATDNFSDDYACTPYIRGTLGAPIPDKGETWIALVRRGRCTFEEKVKHVYQQNAAGVIIYNDKQVMQLEKMQIKGKTRNIAAVITYQNIGQDLSLTLDKGYNVTISIIEGRRGVRTISSLNRTSVLFVSISFIVLMIISLVWLIFYYIQRFRYMQAKDQQSRNLCSVTKKAIMKIPTKTGKFSD-EKDLDSDCCAICIEAYKPTDTIRILPCKHEFHKNCIDPWLIEHRTCPMCKLDVLKFYGYVFLGSEESILEYQPDPPQGLALVEARDESADLNRSRDFVVDFPRVFVLDSGCVVGAREMLFPCRIPERSQSSLSLRQARDWVSLMSNKLEEQQGLRSMRNDEMQQVIK", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : ... *: . .. : * *::* : : . : .*** :. :. * :: . .. * .* * * :* : *:*:::**.***:**: :. ** .*:***:: : .* * * :* **: : *::: *:*. .* ::: * * ..:.* *::************* .*****:**::* .*:*:..*.* ..:**** *:.*:* * .* *.: * : **:***.*: .*.:*:***** *** *:**** ** *******::** * : . . : :: : . * ** . .: :: * . . . . .* . : : *: : : ", "identical_positions": 117, "similar_positions": 115, "identity": "25.27%" }, { "cls_id": "homologset.agr.MGI:1891725", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9QXN4-1", "uniprot_id": "MIOX_RAT", "id": "Q9QXN4-1", "name": "Inositol oxygenase", "aln": "MKVDLG-----PDPSLVYRPDVDPEMAKSKGSFRNY---TSGPLLDRVFTTYKLMHTHQTVDFVMRKRIQFGSFSYKKMTVMEAVDMLDDLVDESDPDVDFPNSFHAFQTAEGIRKAHPDKDWFHLVGLLHDLGKILALWGEPQWAVVGDTFPVGCRPQASVVFCDSTFQDNPDLQDPRYSTELGMYQPHCGLENVLMSWGHDEYLYQMMKFNKFSLPSEAFYMVRFHSFYPWHTGGDYRQLCSQQDLDMLPWVQEFNKFDLYTKCPDLPEVKSLRPYYQGLIDKYCPGILSW", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9QXN5-1", "uniprot_id": "MIOX_MOUSE", "id": "Q9QXN5-1", "name": "Inositol oxygenase", "aln": "MKVDVG-----PDPSLVYRPDVDPEMAKSKDSFRNY---TSGPLLDRVFTTYKLMHTHQTVDFVSRKRIQYGSFSYKKMTIMEAVGMLDDLVDESDPDVDFPNSFHAFQTAEGIRKAHPDKDWFHLVGLLHDLGKIMALWGEPQWAVVGDTFPVGCRPQASVVFCDSTFQDNPDLQDPRYSTELGMYQPHCGLENVLMSWGHDEYLYQMMKFNKFSLPSEAFYMIRFHSFYPWHTGGDYRQLCSQQDLDMLPWVQEFNKFDLYTKCPDLPDVESLRPYYQGLIDKYCPGTLSW", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9UGB7-1", "uniprot_id": "MIOX_HUMAN", "id": "Q9UGB7-1", "name": "Inositol oxygenase", "aln": "MKVTVG-----PDPSLVYRPDVDPEVAKDKASFRNY---TSGPLLDRVFTTYKLMHTHQTVDFVRSKHAQFGGFSYKKMTVMEAVDLLDGLVDESDPDVDFPNSFHAFQTAEGIRKAHPDKDWFHLVGLLHDLGKVLALFGEPQWAVVGDTFPVGCRPQASVVFCDSTFQDNPDLQDPRYSTELGMYQPHCGLDRVLMSWGHDEYMYQVMKFNKFSLPPEAFYMIRFHSFYPWHTGRDYQQLCSQQDLAMLPWVREFNKFDLYTKCPDLPDVDKLRPYYQGLIDKYCPGILSW", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q4V8T0-1", "uniprot_id": "MIOX_DANRE", "id": "Q4V8T0-1", "name": "Inositol oxygenase", "aln": "----MG-----PDPSLAYRPECH---EKDKTEFRNF---ENGDLFDRVFNTYKLMHTHQTLDFVKQKHQVWSNCSHFSLSMMDSIDSLDELVDESDPDVDFPNSFHAFQTAEGIRREHPDKDWFQLVGLIHDVGKVMALYSEPQWAVVGDTYPVGCKFQNSIVFRNSTFEGNPDGKNPAPNTEFGIYEPQCGLDKVLMSWGHDEYLYRVMKFNKCTIPEEGLYMIRFHSFYPWHSNGDYMHLCNEKDQQMLPWVKEFNKFDLYTKSTELPDVERLKPYYQSLIDKYCPGVLQW", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VTU9-1", "uniprot_id": "Q9VTU9_DROME", "id": "Q9VTU9-1", "name": "Inositol oxygenase", "aln": "MRILAENQVQLLDPSELMRPEPT-FADKNPSKFRDYSMDTTDPLKERVRQTYRQMHLNQTVDFVKGRREHWLKFNTIKMTVREALEKLNDLVDESDPDLDLPNIIHAFQAAERARAEFPEHDWLHLTALIHDLGKIMAFYGEPQWAVVGDTFAVGCRWGDSIVYRDESFEGNPDGDNPAYNTELGIYQPNCGVDNLLMSWGHDEYMYSVLKHNKTKLPHVACNIIRFHSFYPWHNGGDYKHLEAPQDAETKKWVLIFNRYDLYTKSEVVPDIEALWPYYQTLIDKYLPGVLEF", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *** **: *. .**:: .. * :** **: ** :**:*** :: : . .::: ::: *: ********:*:** :****:** * .*::**::*..*:**:**::*::.**********:.***: *:*: :.:*:.*** .:* .**:*:*:*:**::.:*********:* ::*.** .:* . ::*********.. ** :* :* ** **::*****. :*::. * **** ***** ** *.:", "identical_positions": 126, "similar_positions": 84, "identity": "43.0%" }, { "cls_id": "homologset.agr.MGI:1891731", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9WUD1-1", "uniprot_id": "CHIP_MOUSE", "id": "Q9WUD1-1", "name": "E3 ubiquitin-protein ligase CHIP", "aln": "MKGKEEKEGGARLGTGGGGSPDKSPSAQELKEQGNRLFVGRKYPEAAACYGRAITRNPLVAVYYTNRALCYLKMQQPEQALADCRRALELDGQSVKAHFFLGQCQLEMESYDEAIANLQRAYSLAKEQRLNFGDDIPSALRIAKKKRWNSIEERRIHQESELHSYLTRLIAAERERELEECQRNHEGHEDDGHIRAQQACIEAKHDKYMADMDELFSQVDEKRKKRDIPDYLCGKISFELMREPCITPSGITYDRKDIEEHLQRVGHFDPVTRSPLTQEQLIPNLAMKEVIDAFISENGWVEDY", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A6HD62-1", "uniprot_id": "CHIP_RAT", "id": "A6HD62-1", "name": "E3 ubiquitin-protein ligase CHIP", "aln": "MKGKEEKEGGARLGTGGGGSPDKSPSAQELKEQGNRLFVGRKYPEAAACYGRAITRNPLVAVYYTNRALCYLKMQQPEQALADCRRALELDGQSVKAHFFLGQCQLEMESYDEAIANLQRAYSLAKEQRLNFGDDIPSALRIAKKKRWNSIEERRIHQESELHSYLTRLIAAERERELEECQRNHEGDEDDGHIRAQQACIEAKHDKYMADMNELFSQVDEKRKKRDIPDYLCGKISFELMREPCITPSGITYDRKDIEEHLQRVGHFDPVTRSPLTQEQLIPNLAMKEVIDAFISENGWVEDY", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9UNE7-1", "uniprot_id": "CHIP_HUMAN", "id": "Q9UNE7-1", "name": "E3 ubiquitin-protein ligase CHIP", "aln": "MKGKEEKEGGARLGAGGG-SPEKSPSAQELKEQGNRLFVGRKYPEAAACYGRAITRNPLVAVYYTNRALCYLKMQQHEQALADCRRALELDGQSVKAHFFLGQCQLEMESYDEAIANLQRAYSLAKEQRLNFGDDIPSALRIAKKKRWNSIEERRIHQESELHSYLSRLIAAERERELEECQRNHEGDEDDSHVRAQQACIEAKHDKYMADMDELFSQVDEKRKKRDIPDYLCGKISFELMREPCITPSGITYDRKDIEEHLQRVGHFDPVTRSPLTQEQLIPNLAMKEVIDAFISENGWVEDY", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F1Q8K3-1", "uniprot_id": "F1Q8K3_DANRE", "id": "F1Q8K3-1", "name": "E3 ubiquitin-protein ligase CHIP", "aln": "MEKMAS-------------SPEKSSSAQELKEQGNRLFLSRKYQEAVTCYSKAINRNPSVAVYYTNRALCYVKLQQYDKALADCKHALELDSQSVKAHFFLGQCQLELENYEEAIGNLQRAYNLAKEQRLNFGDDIPSALRIAKKKRWNSIEEKRISQENELHAYLSKLILAEKERELDDRVK----QSDDSQNGGDISKMKSKHDKYLMDMDELFSQVDEKRKKREIPDYLCGKISFELMREPCITPSGITYDRKDIEEHLQRVGHFDPVTRSPLTQDQLIPNLAMKEVIDAFIQENGWVEDY", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9XYW6-1", "uniprot_id": "Q9XYW6_DROME", "id": "Q9XYW6-1", "name": "E3 ubiquitin-protein ligase CHIP", "aln": "MTTKHIY-------------STTNLSDLQLKEQGNCLFAARKYDDAINCYSKAIIKNPTNATYFTNRALCNLKLKRWELCCQDSRRALDIDGNLLKGHFFLGQGLMEIDNFDEAIKHLQRAYDLSKEQKQNFGDDITLQLRLARKKRWNVMEEKRIQQEIELQSYLNGLIKGDMESRLANLKLN--GNVHDEQLKDKQQEIEQECDDHIKELNNIFSKVDERRKKREVPDFLCGKISFEILTDPVITPSGITYERKDIEEHLQRVGHFDPVTRVKLTQDQLIPNFSMKEVVDSFIAENEWSLDY", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P25638-1", "uniprot_id": "TAH1_YEAST", "id": "P25638-1", "name": "TPR repeat-containing protein associated with Hsp90", "aln": "-----------------------MSQFEKQKEQGNSLFKQGLYREAVHCYDQLITAQPQNPVGYSNKAMALIKLGEYTQAIQMCQQGLRYTS-TAEHVAIRSKLQYRLELAQGAVGSVQIPVVEVDELPEGYDRS-------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . : ***** ** * :* **.: * :* .. ::*:*:. :*: . . .::.* . : : .: .:: : *: :* . .* .:. . ", "identical_positions": 20, "similar_positions": 38, "identity": "6.58%" }, { "cls_id": "homologset.agr.MGI:1891740", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0ABK0LXX0-1", "uniprot_id": "A0ABK0LXX0_RAT", "id": "A0ABK0LXX0-1", "name": "", "aln": "-MKPD---SAREPEPLSPGRG----AEAEGRWRERGEADTERQRTRERQEATLAGLAELGYLRQRQELLVRGALRCSGAVGTVAPRAGELRGDAAQRSRLEEKFLEENILLLRRQLNCLRRRDAGLLNQLQELDKQISDLRLDVEKTSEEHLETDSRPSSGFYELSDGASGSLSNSSNSVFSECLSSCHSSTCFCSPLEAALTISDGCPKS-------------------------------------ADVNPKYQCDLVSKNGNDVYRYPSPLHAVAVQSPMFLLCLTGNSLREEEGLGNHASDICIGSELNATKMDNSLPSPSSLWPASQPASSKKMDGYILSLVQKKTHPVRTNKPRTSVNADPTKGLLRNGSVCVRAPSSVP-QGSNVNLKNTKQMCLPCGGIPSLENGPFSPPKQRSKDSKTDQSES-KRLALQEGCSVGTAMEPQSKHLPKIAKAASQELVRCQAG-LGESMKESNQVSAVSPKTSPGGGPVASTESKALQLQKKMPQKSSLQALP------------AVDRPSLDFKSEGSS-QSLEEG-HLVKAQFIPGQQAGARPHR-AHRNPGVARSATLKARGQAAT--EHGLPTVREKPRAVGKKCRFPDDLD-TNKKLRKASSKGRRS-SGLPDASLPGRPLGTGGHRAGS-RAHAHGR--EPVVAKPKHKRTDYRR-WKSSAEVSYEEALRRARR-ARREHGGAYPVAVAVPYPSPYAYVASDSEYSAECESLFHSTVVDTSEDDQSNYTTNCFGDSESSVSEGDFVGESTTTSDSEESGGLIWSQFVQTLPIQTVTAPDLHTRPTKTFVKIKASHNLKKKILRFRSGSLKLMTTV", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8R4A3-1", "uniprot_id": "DACT1_MOUSE", "id": "Q8R4A3-1", "name": "Dapper homolog 1", "aln": "-MKPD---AAREPEPLSPGRG----AEAEGRWRERGEADTERQRTRERQEATLAGLAELGYLRQRQELLVRGALRCSGTVGTVAPRSGELRGDAAQRSRLEEKFLEENILLLRRQLNCLRRRDAGLLNQLQELDKQISDLRLDVEKTSEEHLETDSRPSSGFYELSDGASGSLSNSSNSVFSECLSSCHSSTCFCSPLEAALTISDGCPKS-------------------------------------ADVNPKYQCDLVSKNGNDVYRYPSPLHAVAVQSPMFLLCLTGNTLREEEGLGSHASDICIGSELNATKTDNSLPSPSSLWSASHPASSKKMDGYILSLVQKKTHPVRTNKPRTSVNADPTKGLLRNGSVCVRAPSGVP-PGSSVNFKNTKQMCLPAGGITSLENGPFSPPKQRSKDSKTDQLES-KRLALPESCSAGAAMEPQSKHVPKAAKAASQELTRCQAG-LGESMKESNQASAVSPKTSPGRGPVAPAESKALQLPKKMSQKNSLQAVP------------ALDRPALDFKSEGSS-QSLEEG-HLVKAQFIPGQQAAARPHR-AHRNPGVARSATLKARGQAAM--EHGLPTVREKPRAAGKKCRFPDDSD-TNKKFRKTSAKGRRS-GGLQDAGLPGRALGTGGHRAGS-RAHAHGR--EPVVAKPKHKRTDYRR-WKSSAEVSYEEALRRARR-ARREHGAAYRVAVALPYASPYAYVPSDSEYSAECESLFHSTVVDTSEDEQSNYTTNCFGDSESSVSEGDFVGESTTTSDSEESGGLIWSQFVQTLPIQTVTAPDLHTRPTKTFVKIKASHNLKKKILRFRSGSLKLMTTV", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9NYF0-1", "uniprot_id": "DACT1_HUMAN", "id": "Q9NYF0-1", "name": "Dapper homolog 1", "aln": "-MKPSPAGTAKELEPPAPARGEQRTAEPEGRWREKGEADTERQRTRERQEATLAGLAELEYLRQRQELLVRGALRGAGGAGAAAPRAGELLGEAAQRSRLEEKFLEENILLLRKQLNCLRRRDAGLLNQLQELDKQISDLRLDVEKTSEEHLETDSRPSSGFYELSDGASGSLSNSSNSVFSECLSSCHSSTCFCSPLEATLSLSDGCPKSADLIGLLEYKEGHCEDQASGAVCRSLSTPQFNSLDVIADVNPKYQCDLVSKNGNDVYRYPSPLHAVAVQSPMFLLCLTGNPLREEDRLGNHASDICGGSELDAVKTDSSLPSPSSLWSASHPSSSKKMDGYILSLVQKKTHPVRTNKPRTSVNADPTKGLLRNGSVCVRAPGGVS-QGNSVNLKNSKQACLPSGGIPSLNNGTFSPPKQWSKESKAEQAES-KRVPLPEGCPSGAASDLQSKHLPKTAKPASQEHARCSAIGTGESPKESAQLSGASPKESPSRGPAPPQENKVVQPLKKMSQKNSLQGVPPATPPLLSTAFPVEERPALDFKSEGSS-QSLEEA-HLVKAQFIPGQQPSVRLHR-GHRNMGVVKNSSLKHRGPALQGLENGLPTVREKTRAGSKKCRFPDDLD-TNKKLKKASSKGRKS-GGGPEAGVPGRPAG-GGHRAGS-RAHGHGR--EAVVAKPKHKRTDYRR-WKSSAEISYEEALRRARR-GRRENVGLYPAPVPLPYASPYAYVASDSEYSAECESLFHSTVVDTSEDEQSNYTTNCFGDSESSVSEGEFVGESTTTSDSEESGGLIWSQFVQTLPIQTVTAPDLHNHPAKTFVKIKASHNLKKKILRFRSGSLKLMTTV", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6QZN6-1", "uniprot_id": "DACT1_DANRE", "id": "Q6QZN6-1", "name": "Dapper homolog 1", "aln": "MNEWSEMLVCRDYCALMMRDR----KECDARCCRDGEG--ERVRARERLDATVAGLTELEYLRQRQELLVRSVLSCPEAAGQDKP---CLTVDDSYLN-TEEKLLEENILLLRKQLNCLRRRDAGLINQLQELDRQISDLRLDTE-TSHEHVETDSRPSSGFYDLSDGASGSLSNSSNSVFSECLSSCRSTTCLCTPLDTSLCASEGRLKPADDPGSCAECDCHCEDSSSGTVRRSLSASYSPSPDSSCDGISKFHCDLIAKNGNDVYRYPSPLHAVAVQSPIFIQSMT-SHLKDDCNFSKPGEALN-----DEQKPEQVVGSQTSSWHASQMLPNKKLDSYIYGLLQRRAQPLRTNKPRTSINTDPSKSILRQASLCSRAPASVQAQQWTSDLKPNWQTCLQDASATSTEPSTASPQRQWSAESKGGTPQNGAYLSSSQPQNSYSTTNENTNCLLKKKVSGTSKGQLLSAT-PKDCPDLGSPKAVSSPKLN-KHCFYNVEDNKTGQAMKASPLKRSPKTQTSLSCG------KDSEQLAQELVSLGSSSQSQDEGGPLVSAQYIPAQKQNVNLQKGGTKNIKIVKVKNSASSKSRPQVFEHVSETVRDKHRTGSRRTRQVDEVHHLHKSSKKASAKTKRIPASIPEGRILERHTSSSGARSSAQRHHGHHRHHEAVLAKPKYKRNDFHRRPRGLHEIPYEEAYRRAHRRQKREMLSHMYLPSNAHYTSPYAYVGSDSEYSAECASLFHSTILDTSEDERSNYTTNCFGDSESSASEADYVAESSTSSDSEGSAGVNWRQISQAG----SGSHGMTSAQAKAFVKIKASHNLKKKILRFRSGSLKLMTTV", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . .:: . * :.* . **. ** *:*** :**:***:** ***********..* . .* * * : : . ***:*********:************:*******:********.* **.**:***********:************************:*:**:*:**:::* *:* *. .* .*::***::*********************:*: .:* . *::: :.. .. : : * :. : * :* * **: ..**:*.** .*:*::::*:********:*:**:*.:**:.*:* ***..* . ::* . * ** .. .* : .. ** :* * :** :. :. : :: : ::: : * ..:.: .* :. . . : *** . :.*. * * . * * : . :: : :: * *** ** :*. **.**:**.*: .. :: . :* :.: . *: ***:* *: .:: * *: . :*. :*:*:* :: .. :. : * . .* *:.: * *.* * *.*:****:**.*::* :. *:.**** ***:* :** . . *.****** ********* ******::*****::**************.**.::*.**:*:**** *.*: * *: *: : .: . :*:****************************", "identical_positions": 345, "similar_positions": 210, "identity": "40.59%" }, { "cls_id": "homologset.agr.MGI:1891748", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q5RKJ1-1", "uniprot_id": "MAEA_RAT", "id": "Q5RKJ1-1", "name": "E3 ubiquitin-protein transferase MAEA", "aln": "MAVQESAAQLSMTLKVQEYP-TLKVPYETLNKRFRAAQKNIDRETSHVTMVVAELEKTLSS--CPAVDSVVSLLDGVVEKLSVLKRKAVESIQAEDESAKLCKRRIEHLKEHSSDQPAAAS---------------MWKRKRMDRMMVEHLLRCG----------YYNTAVKLARQSGIEDLVNIEMFLTAKEVEESLERRE-TATCLAWCHDNKSRLRKMKSCLEFSLRIQEFIELVRQNKRLDAVRHARKHFSQAEGSQLDEVRQVMGMLAFP-------PDTHISP---------------------------------------------------------YKDLLDPARWRMLIQQFRYDNYRLHQLGNSSVFTLTLQAGLSAIKTPQCYK----EDGSS-----------------------KSPDCPVCSRSLNKLAQPLPMAHCANSRLVCK-ISGDVMNENNPPMMLPNGYVYGYNSLLSIRQDDKVVCPRTKEVFHFSQAEKVYIM", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q4VC33-1", "uniprot_id": "MAEA_MOUSE", "id": "Q4VC33-1", "name": "E3 ubiquitin-protein transferase MAEA", "aln": "MAVQESAAQLSMTLKVQEYP-TLKVPYETLNKRFRAAQKNIDRETSHVTMVVAELEKTLSS--CPAVDSVVSLLDGVVEKLSVLKRKAVESIQAEDESAKLCKRRIEHLKEHSSDQPAAAS---------------MWKRKRMDRMMVEHLLRCG----------YYNTAVKLARQSGIEDLVNIEMFLTAKEVEESLERRE-TATCLAWCHDNKSRLRKMKSCLEFSLRIQEFIELVRQNKRLDAVRHARKHFSQAEGSQLDEVRQVMGMLAFP-------PDTHISP---------------------------------------------------------YKDLLDPARWRMLIQQFRYDNYRLHQLGNSSVFTLTLQAGLSAIKTPQCYK----EDGSS-----------------------KSPDCPVCSRSLNKLAQPLPMAHCANSRLVCK-ISGDVMNENNPPMMLPNGYVYGYNSLLSIRQDDKVVCPRTKEVFHFSQAEKVYIM", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q7L5Y9-1", "uniprot_id": "MAEA_HUMAN", "id": "Q7L5Y9-1", "name": "E3 ubiquitin-protein transferase MAEA", "aln": "MAVQESAAQLSMTLKVQEYP-TLKVPYETLNKRFRAAQKNIDRETSHVTMVVAELEKTLSG--CPAVDSVVSLLDGVVEKLSVLKRKAVESIQAEDESAKLCKRRIEHLKEHSSDQPAAAS---------------VWKRKRMDRMMVEHLLRCG----------YYNTAVKLARQSGIEDLVNIEMFLTAKEVEESLERRE-TATCLAWCHDNKSRLRKMKSCLEFSLRIQEFIELIRQNKRLDAVRHARKHFSQAEGSQLDEVRQAMGMLAFP-------PDTHISP---------------------------------------------------------YKDLLDPARWRMLIQQFRYDNYRLHQLGNNSVFTLTLQAGLSAIKTPQCYK----EDGSS-----------------------KSPDCPVCSRSLNKLAQPLPMAHCANSRLVCK-ISGDVMNENNPPMMLPNGYVYGYNSLLSIRQDDKVVCPRTKEVFHFSQAEKVYIM", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q7SXR3-1", "uniprot_id": "MAEA_DANRE", "id": "Q7SXR3-1", "name": "E3 ubiquitin-protein transferase MAEA", "aln": "MAVQETAAQLSMALKVQEYP-TLKVPYETLNKRFRAAQKNIDRETSHVTMVVAELEKTLSS--FPVVDTVVSLLDGVVEKLSALKRKAAESIQAEDESAKLCKRRIEHLKEHSSDQPASVN---------------VWKKKRMDRMMVEHLLRCG----------YYNTAVKLARQSGIEDLVNIEMFLTAKEVEESLERQE-TATCLAWCHDNKSRLRKMKSCLEFSLRIQEFIELIRQNKRMDAVRHARKHFSQAEGGQLDEVRQVMGMLAFP-------SDTHISP---------------------------------------------------------YKDLLDPARWKMLIQQFRYDNYRLHQLGNNSVFTITLQAGLSAIKTPQCYK----EDGTS-----------------------KNPDCPVCSKSLNKLAQPLPMAHCANSRLVCK-ISGEVMNENNPPMMLPNGYVYGYNSLLSIRQDDKVICPRTKEVFNFSQAEKVYIM", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P40492-1", "uniprot_id": "FYV10_YEAST", "id": "P40492-1", "name": "GID complex subunit 9", "aln": "MAEKSIFNEPDVDFHLKLNQQLFHIPYELLSKRIKHTQAVINKETKSLHEHTAALNQIFEHNDVEHDELALAKITEMIRKVDHIERFLNTQIKSYCQILNRIKKRLEFFHELKDIKSQNSGTSHNGNNEGTRTKLIQWYQSYTNILIGDYLTRNNPIKYNSETKDHWNSGVVFLKQSQLDDLIDYDVLLEANRISTSLLHERNLLPLISWINENKKTLTKKSSILEFQARLQEYIELLKVDNYTDAIVCFQRFLLPFVKSNFTDLKLASGLLIFIKYCNDQKPTSSTSSGFDTEEIKSQSLPMKKDRIFQHFFHKSLPRITSKPAVNTTDYDKSSLINLQSGDFERYLNLLDDQRWSVLNDLFLSDFYSMYGISQNDPLLIYLSLGISSLKTRDCLHPSDDENGNQETETATTAEKEVEDLQLFTLHSLKRKNCPVCSETFKPITQALPFAHHIQSQLFENPILLPNGNVYDSKKLKKLAKTLKKQNLISLNPG-QIMDPVDMKIFCESDSIKMYPT", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "** :. : .: :::: :::*** *.**:: :* *::**. : .* *:: :. : .:: : ::.*:. ::* .*:: : : *:*:*.::* .. :. . * :. : :: ::* * . ::*:.* : :** ::**:: :::* *:.:. ** :.. . ::* ::**. * * .* ***. *:**:***:: :: **: ::.: .:: ::: . *:* * . : *. * :*** ** :* : * * * :: :.:.. : : *. *:*::** :* : *:*.. * :*****.::: ::*.**:** :*:*. : * * :. : . . :.*:*:. . ::: * ::* *:: *:* ", "identical_positions": 95, "similar_positions": 163, "identity": "18.38%" }, { "cls_id": "homologset.agr.MGI:1891749", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9P2S5-1", "uniprot_id": "WRP73_HUMAN", "id": "Q9P2S5-1", "name": "WD repeat-containing protein WRAP73", "aln": "MNFSEVFKLSSLLCKFSPDGKYLASCVQYRLVVRDVNTLQILQLYTCLDQIQHIEWSADSLFILCAMYKRGLVQVWSLEQPEWHCKIDEGSAGLVASCWSPDGRHILNTTEFHLRITVWSLCTKSVSYIKYPKACLQGITFTRDGRYMALAERRDCKDYVSIFVCSDWQLLRHFDTDTQDLTGIEWAPNGCVLAVWDTCLEYKILLYSLDGRLLSTYSAYEWSLGIKSVAWSPSSQFLAVGSYDGKVRILNHVTWKMITEFGHPAAINDPKIVVYKEAEKSPQLGLGCLSFPPPRAGAGPLPSSESKYEIASVPVSLQTLKPVTDRANPKIGIGMLAFSPDSYFLATRNDNIPNAVWVWDIQKLRLFAVLEQLSPVRAFQWDPQQPRLAICTGGSRLYLWSPAGCMSVQVPGEGDFAVLSLCWHLSGDSMALLSKDHFCLCFLETEAVVGTACRQLGGHT--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9JM98-1", "uniprot_id": "WRP73_MOUSE", "id": "Q9JM98-1", "name": "WD repeat-containing protein WRAP73", "aln": "MNFSESFKLSGLLCRFSPDGKYLASCVQYRLVIRDVTTLQILQLYTCLDQIQHIEWSADSLFILCAMYRRGLVQVWSLEQPEWHCKIDEGSAGLVASCWSPDGRHILNTTEFHLRITVWSLCTKSVSYIKYPKACQQGLTFTRDGRYLALAERRDCRDYVSIFVCSDWQLLRHFDTDTQDLTGIEWAPNGCVLAAWDTCLEYKVLLYSLDGRLLSAYCAYEWSLGIKSVAWSPSSQFLAIGSYDGKVRLLNHVTWKMITEFGHPATINNPKTVVYKEAEKSPLLGLGHLSFPPPRAMAGALSTSESKYEIASGPVSLQTLKPVADRANPRMGVGMLAFSSDSYFLASRNDNVPNAVWIWDIQKLKLFVVLEHMSPVRSFQWDPQQPRLAICTGGSKVYLWSPAGCVSVQVPGEGDFPVLGLCWHLSGDSLALLSKDHFCLCFLETKERVGTAYEQRDGMPRT", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "B8A4V4-1", "uniprot_id": "B8A4V4_DANRE", "id": "B8A4V4-1", "name": "", "aln": "MNFSEVFKQSNQLCKVSPDGKYLATCVQYRLVVRDIGTLQIVHLYTCLDQVMHMEWSSDSLFILCAMYKRGLVQVWSLEQPDWHCKIDEGSIGLVSSRWSPDGRHILNTTEFNLRITVWSLCTKSVSYIKYPKACQKGMDFTADGRYMALAERRDCKDYISVFVCDDWHLLRHFESETQDLAGLEWSPNGCVLAVWDNCLEYKILLYSLDGRLLSFYSAYEWSLGIKSVAWSPSSQFLAIGSYDEKVRILNHITWKKITEFEHPATITNSKAVVFKEVEKRPVVS-EDLSIR-QLTVDNALFSTQSKYEITQLPVQVPVVKPDPERANPKIGISAVAFSADNRYLATKNDNMPQSLWVWDMQKFSLLAVLEQTAPVRCFVWDPHLPRLALCTGNTKLYMWSPAGCISVTVPVEG-FQVQSLFWHCTGSSLVLLSKDQLCLCYTDAEEQK-------------", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "***** ** *. **:.********:*******:**: ****::*******: *:***:**********:************:********* ***:* **************:********************** :*: ** ****:********:**:*:***.**:*****:::****:*:**:*******.**.*****:*********** *.*********************:**** ***:***:*** **** ***:*.:.* **:**.** * :. **: : ..* :::*****:. **.: .:** .:****::*:. :***.*. :**::***:*:::*:**:**: *:.***: :***.* ***: ****:***.:::*:******:** ** ** * * .* ** :*.*:.*****::***: ::: ", "identical_positions": 302, "similar_positions": 100, "identity": "65.37%" }, { "cls_id": "homologset.agr.MGI:1891750", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I5ZT87-1", "uniprot_id": "A0A8I5ZT87_RAT", "id": "A0A8I5ZT87-1", "name": "", "aln": "MAHYKAADSKREQFRRYLEKSGVLDTLTKVLVALYEEPEKPTSALDFLKHHLGAATPENPEIELLRLELAEMKEKYEAT--------------------------VEENKKLKAKLVQYEPPQEEKRAE-------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9EQS3-1", "uniprot_id": "MYCBP_MOUSE", "id": "Q9EQS3-1", "name": "c-Myc-binding protein", "aln": "MAHYKAADSKREQFRRYLEKSGVLDTLTKVLVALYEEPEKPTSALDFLKHHLGAATPENPEIELLRLELAEMKEKYEAT--------------------------VEENKKLKAKLVQYEPPQEEKRAE-------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q99417-1", "uniprot_id": "MYCBP_HUMAN", "id": "Q99417-1", "name": "c-Myc-binding protein", "aln": "MAHYKAADSKREQFRRYLEKSGVLDTLTKVLVALYEEPEKPNSALDFLKHHLGAATPENPEIELLRLELAEMKEKYEAI--------------------------VEENKKLKAKLAQYEPPQEEKRAE-------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VG76-1", "uniprot_id": "MYCBP_DROME", "id": "Q9VG76-1", "name": "Myc-binding protein", "aln": "-MSFKPIDPKRDEIRRYLERGSVLDSLTKLFIRVIK--ERPENPMDYIRNHIGVVRHQHDKYERLQQDLQLANEEIQRLRAIINGINPDVLQGHQPVASSEVVVATEAPQTVAESTEAAEQQQQQQQQENGETELEKPNESSADVAEITAAVEACQIEGNSVVTTDEAAQPSPTVQAEASGSSE", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :*. *.**:::*****:..***:***::: : : *:* ..:*::::*:*.. :: : * *: :* :*: : .* :.: . * *:::: * ", "identical_positions": 28, "similar_positions": 43, "identity": "15.22%" }, { "cls_id": "homologset.agr.MGI:1891751", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q921N8-1", "uniprot_id": "GPS2_MOUSE", "id": "Q921N8-1", "name": "G protein pathway suppressor 2", "aln": "MPALLERPKLSNAMARALHRHIMMERERKRQEEEEVDKMMEQKMKEEQERRKKKEMEERMSLEETKEQILKLQEKLSALQEEKHQLFLQLKKVLHEEEKRRRKEQSDLTTLTSAAYQQSLTVHTGTHLLSMQGSPGGHNRPGTLMAADRAKQMFGPQVLTTRHYVGSAAAFAGTPEHGQFQGSPGGAYGTAQPPPHYGPTQPAYSPSQQLRAPSAFPAVQYLSQPQPQPYAVHGHFQPTQTGFLQPGSTLSLQKQMEHANQQTSFSDSSSLRPMHPQALHPAPGLLASPQLPVQIQAAGK--------------SGFATTSQ-------------------------------------------PGP------RLPFIQHSQNPRFYHK----------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q13227-1", "uniprot_id": "GPS2_HUMAN", "id": "Q13227-1", "name": "G protein pathway suppressor 2", "aln": "MPALLERPKLSNAMARALHRHIMMERERKRQEEEEVDKMMEQKMKEEQERRKKKEMEERMSLEETKEQILKLEEKLLALQEEKHQLFLQLKKVLHEEEKRRRKEQSDLTTLTSAAYQQSLTVHTGTHLLSMQGSPGGHNRPGTLMAADRAKQMFGPQVLTTRHYVGSAAAFAGTPEHGQFQGSPGGAYGTAQPPPHYGPTQPAYSPSQQLRAPSAFPAVQYLSQPQPQPYAVHGHFQPTQTGFLQPGGALSLQKQMEHANQQTGFSDSSSLRPMHPQALHPAPGLLASPQLPVQMQPAGK--------------SGFAATSQ-------------------------------------------PGP------RLPFIQHSQNPRFYHK----------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8I6GLY5-1", "uniprot_id": "A0A8I6GLY5_RAT", "id": "A0A8I6GLY5-1", "name": "", "aln": "MPALLERPKLSNAMARALHRHIMMERERKRQEEEEVDKMMEQKMKEEQERRKKKEMEERMSLEETKEQILKLQQKLSALQEEKHQLFLQLKKVLHEEEKRRRKEQSDLTTLTSAAYQQSLTVHTGTHLLSMQGSPGGHNRPGTLMAADRAKQMFGPQVLTTRHYVGSAAAFAGTPEHGQFQGSPGGAYGTAQPPPHYGPTQPAYSPSQQLRAPSAFPAVQYLSQPQPQPYAVHGHFQPTQTGFLQPGSALSLQKQMEHANQQTSFSDSSSLRPMHPQALHPAPGLLASPQLPVQIQAAGKALPPPANRALDSLSSNTARTHDSITSNHQITPTHPPSLRVGSYVSQTNKMYKIYLPSCQSTVYLLPKPQKAVSYKASFSQQKQLSWGLHIKLVVLFRFDF", "tax_id": 10116, "tax_name": "Rat" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "************************************************************************::** **************************************************************************************************************************************************************************.:**************.******************************:*.*** *. * * : * * : .* *:.* . * ", "identical_positions": 301, "similar_positions": 14, "identity": "75.25%" }, { "cls_id": "homologset.agr.MGI:1891763", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q5BJ92-1", "uniprot_id": "PP4C_RAT", "id": "Q5BJ92-1", "name": "Serine/threonine-protein phosphatase 4 catalytic subunit", "aln": "----MAEISDLDRQIEQLRRCELIKESEVKALCAKAREILVEESNVQRVDSPVTVCGDIHGQFYDLKELFRVGGDVPETNYLFMGDFVDRGFYSVETFLLLLALKVRYPDRITLIRGNHESRQITQVYGFYDECLRKYGSVTVWRYCTEIFDYLSLSAIIDGKIFCVHGGLSPSIQTLDQIRTIDRKQEVPHDGPMCDLLWSDPEDTTGWGVSPRGAGYLFGSDVVAQFNAANDIDMTCRAHQLVMEGYKWHFNETVLTVWSAPNYCYRCGNVAAILELDEHLQKDFIIFEAAPQETRG----IPSKKPVADYFL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P60510-1", "uniprot_id": "PP4C_HUMAN", "id": "P60510-1", "name": "Serine/threonine-protein phosphatase 4 catalytic subunit", "aln": "----MAEISDLDRQIEQLRRCELIKESEVKALCAKAREILVEESNVQRVDSPVTVCGDIHGQFYDLKELFRVGGDVPETNYLFMGDFVDRGFYSVETFLLLLALKVRYPDRITLIRGNHESRQITQVYGFYDECLRKYGSVTVWRYCTEIFDYLSLSAIIDGKIFCVHGGLSPSIQTLDQIRTIDRKQEVPHDGPMCDLLWSDPEDTTGWGVSPRGAGYLFGSDVVAQFNAANDIDMICRAHQLVMEGYKWHFNETVLTVWSAPNYCYRCGNVAAILELDEHLQKDFIIFEAAPQETRG----IPSKKPVADYFL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P97470-1", "uniprot_id": "PP4C_MOUSE", "id": "P97470-1", "name": "Serine/threonine-protein phosphatase 4 catalytic subunit", "aln": "----MAEISDLDRQIEQLRRCELIKESEVKALCAKAREILVEESNVQRVDSPVTVCGDIHGQFYDLKELFRVGGDVPETNYLFMGDFVDRGFYSVETFLLLLALKVRYPDRITLIRGNHESRQITQVYGFYDECLRKYGSVTVWRYCTEIFDYLSLSAIIDGKIFCVHGGLSPSIQTLDQIRTIDRKQEVPHDGPMCDLLWSDPEDTTGWGVSPRGAGYLFGSDVVAQFNAANDIDMICRAHQLVMEGYKWHFNETVLTVWSAPNYCYRCGNVAAILELDEHLQKDFIIFEAAPQETRG----IPSKKPVADYFL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A9JRC7-1", "uniprot_id": "PP4CB_DANRE", "id": "A9JRC7-1", "name": "Serine/threonine-protein phosphatase 4 catalytic subunit B", "aln": "----MGDMSDLDRQIDQLRRCELIKENEVKALCAKAREILVEESNVQRVDSPVTVCGDIHGQFYDLKELFRVGGDVPETNYLFMGDFVDRGFYSVETFLLLLALKVRYPDRITLIRGNHESRQITQVYGFYDECLRKYGSVTVWRYCTEIFDYLSLSAIIDGKIFCVHGGLSPSIQTLDQIRTIDRKQEVPHDGPMCDLLWSDPEDTTGWGVSPRGAGYLFGSDVVAQFNAANDIDMICRAHQLVMEGYKWHFNETVLTVWSAPNYCYRCGNVAAILELDEHLQKEFIIFEAAPQETRG----IPSKKPVADYFL", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A8WGP3-1", "uniprot_id": "PP4CA_DANRE", "id": "A8WGP3-1", "name": "Serine/threonine-protein phosphatase 4 catalytic subunit A", "aln": "MCVIMGDFTDLDRQIEQLRRCELIKENEVKALCAKAREILVEESNVQSVDSPVTVCGDIHGQFYDLKELFRVGGEVPETNYLFMGDFVDRGFYSVETFLLLLALKVRYPDRITLIRGNHESRQITQVYGFFDECHRKYGSATVWRYCTEIFDYLSLSAIVDGKIFCVHGGLSPSIQTLDQIRTIDRKQEVPHDGPMCDLLWSDPEDTTGWGVSPRGAGYLFGSDVVAQFNAANDISMICRAHQLVMEGYKWHFNDTVLTVWSAPNYCYRCGNVAAILELDEHLQKEFIIFEAAPQETRG----LPSKKPVADYFL", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "O76932-1", "uniprot_id": "PP4C_DROME", "id": "O76932-1", "name": "Serine/threonine-protein phosphatase 4 catalytic subunit", "aln": "----MSDYSDLDRQIEQLKRCEIIKENEVKALCAKAREILVEEGNVQRVDSPVTVCGDIHGQFYDLKELFKVGGDVPEKNYLFMGDFVDRGYYSVETFLLLLALKVRYPDRITLIRGNHESRQITQVYGFYDECLRKYGSTAVWRYCTEIFDYLSLSAIIDGKIFCVHGGLSPSIQYLDQIRSIDRKQEVPHDGPMCDLLWSDPEDQTGWGVSPRGAGYLFGSDVVSQFNRTNDIDMICRAHQLVMEGFKWHFNETVLTVWSAPNYCYRCGNVAAILELNEYLHRDFVIFEAAPQESRG----IPSKKPQADYFL", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P32345-1", "uniprot_id": "PP4C_YEAST", "id": "P32345-1", "name": "Serine/threonine-protein phosphatase 4 catalytic subunit", "aln": "-------MMDLDKIIASLRDGKHIPEETVFRLCLNSQELLMNEGNVTQVDTPVTICGDIHGQLHDLLTLFEKSGGVEKTRYIFLGDFVDRGFYSLESFLLLLCYKLRYPDRITLIRGNHETRQITKVYGFYDEVVRKYGNSNVWRYCCEVFDYLSLGAIINNSIFCVHGGLSPDMTTVDEIRTIDRKQEVPHEGAMCDLLWSDPEDVDTWSLSPRGAGFLFGKREVDQFLEKNNVELIARAHQLVMEGYKEMFDGGLVTVWSAPNYCYRCGNVAAVLKIDDDLNREYTIFEAVQAQNEVGNAIIPTKKSQMDYFL", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ***: * .*: : * *. * ** :::*:*::*.** **:***:*******::** **. .* * :..*:*:*******:**:*:*****. *:**************:****:****:** ****. ***** *:******.**::..**********.: :*:**:*********:*.*********** *.:******:***. * ** *::.: .*********:* *: ::*****************:*:::: *:::: ****. :.. :*:**. ****", "identical_positions": 182, "similar_positions": 74, "identity": "57.78%" }, { "cls_id": "homologset.agr.MGI:1891766", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P97756-1", "uniprot_id": "KKCC1_RAT", "id": "P97756-1", "name": "Calcium/calmodulin-dependent protein kinase kinase 1", "aln": "-----------------------------------------------------------------------MERSPAVCCQDPR-----------------------AELVERVAAISVAHLEEAEEGPEPASNG-------VDPPPRAR-------------------------------------------------------AASVIPG--SASRPTPVRPSLSARKFSLQERPAGSCLEAQVGPYSTGPASHMSPRAWRR--PTIESHHVAISDTEDCVQLNQYKLQSEIGKGAYGVVRLAYNEREDRHYAMKVLSKKKLLKQYGFPRRPPPRGSQAPQGGPAKQLLPLERVYQEIAILKKLDHVNVVKLIEVLDDPAEDNLYLVFDLLRKGPVMEVPCD---------KPFPEEQARLYLRDIILGLEY------------------LHCQKIVHRDIKPSNLLLGDDGHVKIADFGVSN-------QFEGNDAQLS--STAGTPAFMAPEAISDTGQSFSGKALDVWATGVTLYCFVYGKCPFIDEYILALHRKIKNEAVVFPEEPEVS------------EELKDLILKMLDKNPETRIGVSDIKLHPWVTKHGEEPLP--------------SEEEHCSVVEVTEEEVKNSVKLIPSWTTVILVKSMLRK-----------------------RSFGNPFEPQAR----------------REERSMSAPGNLLLKEG------------------CGEGGKSPELPGVQEDEAAS-------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8VBY2-1", "uniprot_id": "KKCC1_MOUSE", "id": "Q8VBY2-1", "name": "Calcium/calmodulin-dependent protein kinase kinase 1", "aln": "-----------------------------------------------------------------------MESGPAVCCQDPR-----------------------AELVDRVAAINVAHLEEADEGPEPARNG-------VDPPPRAR-------------------------------------------------------AASVIPG--SASRPTPVRPSLSARKFSLQERPAGSCLGAQVGPYSTGPASHISPRSWRR--PTIESHRVAISDTEDCVQLNQYKLQSEIGKGAYGVVRLAYNESEDRHYAMKVLSKKKLLKQYGFPRRPPPRGSQATQGGPAKQLLPLERVYQEIAILKKLDHVNVVKLIEVLDDPAEDNLYLVFDLLRKGPVMEVPCD---------KPFPEEQARLYLRDIILGLEY------------------LHCQKIVHRDIKPSNLLLGDDGHVKIADFGVSN-------QFEGNDAQLS--STAGTPAFMAPEAISDSGQSFSGKALDVWATGVTLYCFVYGKCPFIDDYILTLHRKIKNEAVVFPEEPEVS------------EDLKDLILRMLDKNPETRIGVSDIKLHPWVTKHGEEPLP--------------SEEEHCSVVEVTEEEVKNSVRLIPSWTTVILVKSMLRK-----------------------RSFGNPFEPQAR----------------REERSMSAPGSLLMKEG------------------CGEGCKSPELPGVQEDEAAS-------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8N5S9-1", "uniprot_id": "KKCC1_HUMAN", "id": "Q8N5S9-1", "name": "Calcium/calmodulin-dependent protein kinase kinase 1", "aln": "-----------------------------------------------------------------------MEGGPAVCCQDPR-----------------------AELVERVAAIDVTHLEEADGGPEPTRNG-------VDPPPRAR-------------------------------------------------------AASVIPG--STSRLLPARPSLSARKLSLQERPAGSYLEAQAGPYATGPASHISPRAWRR--PTIESHHVAISDAEDCVQLNQYKLQSEIGKGAYGVVRLAYNESEDRHYAMKVLSKKKLLKQYGFPRRPPPRGSQAAQGGPAKQLLPLERVYQEIAILKKLDHVNVVKLIEVLDDPAEDNLYLVFDLLRKGPVMEVPCD---------KPFSEEQARLYLRDVILGLEY------------------LHCQKIVHRDIKPSNLLLGDDGHVKIADFGVSN-------QFEGNDAQLS--STAGTPAFMAPEAISDSGQSFSGKALDVWATGVTLYCFVYGKCPFIDDFILALHRKIKNEPVVFPEEPEIS------------EELKDLILKMLDKNPETRIGVPDIKLHPWVTKNGEEPLP--------------SEEEHCSVVEVTEEEVKNSVRLIPSWTTVILVKSMLRK-----------------------RSFGNPFEPQAR----------------REERSMSAPGNLLVKEG------------------FGEGGKSPELPGVQEDEAAS-------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M2BJ77-1", "uniprot_id": "A0A8M2BJ77_DANRE", "id": "A0A8M2BJ77-1", "name": "calcium/calmodulin-dependent protein kinase", "aln": "--------------------------------------------------------------------------MVMAMSSGPG-----------------------GVRVERDP--DSSQTAEMTDRMSVMSLG-------PDS------------------------------------------------------------SSSVLKNGMGVKKAQPKRPHLSGRKMSLQER-----------------GTYMSSRIARQ--PTIESKRVSISDSQDCIQLNQYKLKSEIGKGSYGVVKLAYNEDDDKYYAMKVVSKKKLMKQYGFPRRPPPRGPKAAQGEQPKVLGPLERVYQEIAILKKLDHLNIVKLVEVLDDPAEDNLHMVFELMQKGPVMEVPSD---------SPFSEDQARHYFRDIVLGIEY------------------LHYQKIVHRDIKPSNLLLGDDGHVKIADFGVSN-------QFEGNDALLS--STAGTPAFMAPETLSDNRQSFSGKALDVWAMGVTLYCFVYGKCPFIDEYILALHNKIKSKVVEFPDTPTVS------------EGLKSLVSRMLDKNPDTRITIPEIKVDPWVTQDGKDPLP--------------LEEEHCTVVEVTEEEVQNSVKFVPSLSAVILVKAMLRK-----------------------RSFGNPFECPSR----------------REERSMSAPGSLLMDSWPFRPS--FKLQPSLRKGSSGEAPREAELEDLHEDEPPSS------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A4V2C3-1", "uniprot_id": "A4V2C3_DROME", "id": "A4V2C3-1", "name": "calcium/calmodulin-dependent protein kinase", "aln": "MDLTDPLLITKSQQVNSQEVDFQKKTEDTFPSKFHKNKASCGLLAVNESRCTDHQLQCENNIVGLSLETQIAENSSINVSRELKPHDHTFPKDKQTFKQISDELRKSYENINKVQNIKKSQSVENFEKCSEINLANKCLYTNLNTSPKERNALDKQAMFIKFHSLELCTDKVCSLHIHENFCTDIHKCVVDSESNKPNKMKKCLDYESVKRYPCKVSNEPPQHNTASKPQILYETRPIYPN-----VPYSPYSTPFSSPRSSRRKPAFRESRRISIDKSGSFLQLNQYRLMEQIGQGSYGLVKLAYSEEDSTHYAMKILSKKRLLRQAGLMRR-----------GPRKATSPLDRVYREIAVLKKLDHPNVVKLVEVLDDPLEDSLYMVFELVKQGEVLRIPTD---------NPLSEKRAWSIFRESLLGLEYYTMLSSSAISLKRIFVYTVHHQKIIHADIKPGNLLLTEFGHVKIADLGVCN-------EFLGDDATISNGSTAGTPAFRAPETLIPGQNEYCGRAADVWALGATLYSLIFGNVPFLADSVPLLYEKIKQDSVKFPENHKVT------------ENLKSCIVQMLEKNPTQRITIPQLKTSKWVTSDGDYPLP--------------TEEENCCLVQVDDEDIDSVVRSIPKLDTLILIKTMLKK-----------------------HSFGNPFVKGCSGTSSSLAGCSRIERFIRAGRSNSAPGSYHMSTAR-------------------QPSSDTLLPSLMEHCSTQCNEGTHSFDY---------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P43637-1", "uniprot_id": "TOS3_YEAST", "id": "P43637-1", "name": "Serine/threonine-protein kinase TOS3", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MVLLKEPVQPLPRSSLLYNNAS-------------------NSSSRIKET-----RKVKLLYNPLTKRQILNNFEILATLGNGQYGKVKLARDLGTGALVAIKILNRFEKRSGYSLQLK-----------------VENPRVNQEIEVMKRCHHENVVELYEILNDPESTKVYLVLEYCSRGPVKWCPENKMEIKAVGPSILTFQQSRKVVLDVVSGLEY------------------LHSQGITHRDIKPSNLLISSNGTVKISDFGVAMSTATGSTNIQSSHEQLLKSRALGTPAFFAPELCSTEKEYSCSSAIDIWSLGVTIYCLLFGKLPFNANSGLELFDSIINKPLEFPSYEEMLNGATSGITMEEYTDAKDLLKKLLQKDPDKRIKLADIKVHPFMCHYGKSDAASVLTNLETFHELKVSPPSSCKRVELVSLPVNSSFASLDSVYMENFDHNNLRTGADRNSTYSPSIYDANTLSPSAYHNIGSRESSYSSFSSFTSSTAFASQISIQDAPAIGDQQCLIGESGSSLRVNSCEFPQYTTMSPVGEYPFESTEASLSSTLTPVGNVPQRIKAHLVEGKSNSKDDLRIEADASLVFEASDAQRTRRRMSLYKL", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . * : : : *.* . .. :: . . **::.: :*:* ** *:** . . *:*::.: . .: : ** :** ::*: .* *:*:* *:*:** . .:::*:: :* * * : . :. .:: . : : *:** :* * * * ****.***: . * ***:*:**. :: ... : : ***** *** : .. * *:*: *.*:*.:::*: ** : *. .* .. : **. : *. : ::*:*:* ** :.::* :: *. . . * *:: . :.. . : . : : *:. :.:*. . : : . . : .. .: . .. ", "identical_positions": 85, "similar_positions": 137, "identity": "10.2%" }, { "cls_id": "homologset.agr.MGI:1891767", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9EP78-1", "uniprot_id": "CHST7_MOUSE", "id": "Q9EP78-1", "name": "Carbohydrate sulfotransferase 7", "aln": "----------------------------------------------------MKGRRRRRREYCKFTLLLALYTLLLLLVPSVLDSHSEQ-----DKG-RNCPGLQR--------------------------SLGVWSLEAAAAGEREQGAEVRSLAEGNPDRSPGSPGNLS-AVGEAVTQEKQHIYVHATWRTGSSFLGELFNQHPDVFYLYEPMWHLWQALYPGDAESLQGALRDMLRSLFRCDFSVLRLYAQPGDPGERAPDSANLTTAMLFRWRTNKVICSPPLCPAAPRARADVGLVEDKACESTCPPVSLRALEAECRKYPVVVIKDVRLLDLGVLVPLLRDPGLN-LKVVQLFRDPRAVHNSRLKSRQGLLRESIQVLRTRQRGDHFHRVLLAHGVDARPGGQARALPSAPRADFFLTSALEVICEAWLRDLLFTRGAPAWLRRRYLRLRYEDLVWQPQAQLRRLLRFSGLRTLAALDAFAFNMTRGSAYGADRPFHLSARDAREAVHAWRERLSQEQVRQVETACAPAMRLLAYPRSGDERDRKTVREGETPLETKANWAV", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6XQG8-1", "uniprot_id": "CHST7_RAT", "id": "Q6XQG8-1", "name": "Carbohydrate sulfotransferase 7", "aln": "----------------------------------------------------MKGRRRRRREYCKFTLLLALYTLLLLLVPSVLDSGSEQ-----DKGGRDCPGLQR--------------------------SLGVWSLEAAAAGEREQGAEVRFQAEGNPDRSPRPQGNLS-AIRESVTQEKQHIYVHATWRTGSSFLGELFNQHPDVFYLYEPMWHLWQALYPGNAESLQGALRDMLRSLFRCDFSVLRLYAQPGDPAERAPDSANLTTAMLFRWRTNKVICSPPLCPAAPRARADVGLVEDKACESTCPPVPLRALEAECRKYPVVVIKDVRLLDLGVLVPLLRDPGLN-LKVVQLFRDPRAVHNSRLKSRHGLLRESIQVLRTRQRGDRFQRVLLAHGVGARPGGQSRALPSAPRADFFLTSALEVICEAWLRDLLFTRGAPTWLRRRYLRLRYEDLVWQPQVQLRRLLRFSGLRTLAALDAFAFNMTRGSAYGADRPFHLSARDAREAVHAWRERLSQEQVRQVEAACDPAMRLLAYPRSGDERDVKTVRKGETPLETNANWAT", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9NS84-1", "uniprot_id": "CHST7_HUMAN", "id": "Q9NS84-1", "name": "Carbohydrate sulfotransferase 7", "aln": "----------------------------------------------------MKGRRRRRREYCKFALLLVLYTLVLLLVPSVLDGGRDG-----DKGAEHCPGLQR--------------------------SLGVWSLEAAAAGEREQGAEARAAEEGGANQSPRFPSNLSGAVGEAVSREKQHIYVHATWRTGSSFLGELFNQHPDVFYLYEPMWHLWQALYPGDAESLQGALRDMLRSLFRCDFSVLRLYAPPGDPAARAPDTANLTTAALFRWRTNKVICSPPLCPGAPRARAEVGLVEDTACERSCPPVAIRALEAECRKYPVVVIKDVRLLDLGVLVPLLRDPGLN-LKVVQLFRDPRAVHNSRLKSRQGLLRESIQVLRTRQRGDRFHRVLLAHGVGARPGGQSRALPAAPRADFFLTGALEVICEAWLRDLLFARGAPAWLRRRYLRLRYEDLVRQPRAQLRRLLRFSGLRALAALDAFALNMTRGAAYGADRPFHLSARDAREAVHAWRERLSREQVRQVEAACAPAMRLLAYPRSGEEGDAEQPREGETPLEMDADGAT", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F1QE68-1", "uniprot_id": "F1QE68_DANRE", "id": "F1QE68-1", "name": "Sulfotransferase", "aln": "----------------------------------------------------MKRRLQK-----KYIILILGYSVALLLIPYVLDYRSKSPHIKDGYQQQKCPDLES--------------------------TIALWSSIRSAN---------STEAEDSGNRS----------------QSRTHIYLHATWRTGSSFLGELFNQHPDVFYLYEPMWNMWQALYPGDAGSLQGAVRDMMNSLFRCDFSVLKLYAG----------SSNVSTSFIFGWKTNKVICSEPLCNAYK--KHEIGLVQGDVCS-KCQPKDLRELEKECKKYPVMVIKDVRVLDLAVLVPLMRDPAIN-LQIVQLFRDPRAVHNSRLKSKLALVKESIQVLRSKKQSEKYKRLLVPS-------------NRVHRAENYVSSAMELICDNWLNDMSLVLNAPPWVKRNYIRVKYEDLVLKPVDELQRLYRFANLTLSPAMEKFVMNMTRGRGYSSDKPFLISSRDAKEAIFAWRERLNVEQVKQVEAYCSEVMRQLDYQKRNMDKT-------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VMC4-1", "uniprot_id": "Q9VMC4_DROME", "id": "Q9VMC4-1", "name": "Sulfotransferase domain-containing protein", "aln": "--------------------------------------------------MVSLSRTSKLT--VACVGVYTTYVLFIFFLLPMLMPDPVTLQRSLVS------------------------------------------------------------------YSTSHLGDIR-NLTLDAGGQPIRSMLVTFRGSGALTLLDNLAHQPGCYQHYAPLIAYESRSIAAK-EHHRALD--ELAALYNCDYNKSAEMIQWG-----------MRSPVFRRFYG-----------------AQAKICRSYSQEACWDP---ETMAAVCKLYPFINMAVYN-LRLNLLASLLERKDLN-LNIMLLVRDPRGTIYSRMNNKWCSDERDCEA--------------------------------------------QELCGDMVSDYQMVETLTQAYPQRFSIIRYEDLFLQPDESIKQVFDFYGLPLERNRTRIQKMHPRSGYFFQSSRWKE---LSSQSAFEWISEMMVDDIGAVQDVCGQAMDLWGYRSIQDFNHFSP--ESFQPIMDKAY---", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VMC3-1", "uniprot_id": "Q9VMC3_DROME", "id": "Q9VMC3-1", "name": "Sulfotransferase domain-containing protein", "aln": "MSTGIGSSSSSTEEQQHLELSADLEACSLLGPQDPSNVDTGRTRAKQRLSLNGKRRRSRMSRRANLIGICGVSSLCILLLIATTQHRPLTTPFNQSAGRDQGASVDGGPSNSLARSAFYDRFQQQLQQQQQSSQTAVYNLTATIVDVLSAQRSRILAEMENFEYPRGGAERLT-DMTPETNGTPVRSVVVTSWRSGSTFLGDILNSIPGNFYHYEPLLDFGIKQIRDPDDQELAVQ--NLKNLLNCDYADMIDYLNFG-----------KTHTYLFEHNT-----------------RLWDVCREFP-RFCWRP---AFLTRFCRLFPIQSMKTVR-LRLAQAEKLLEDQSLSSVRIVLLVRDPRGTMQSRRHRVWCGGNEDCEDP-------------------------------------------RLVCQDLRDDYKTAEVLLLKYPSRFRTVRYEDLSLSPSEMTQDILQFYGLPFDPAVEEFLDTHTKVNIGGVSSTYRD---SRS-APFHWMQDLKPEEIKQIQDVCTEAMDLWGYRRIENFNNFSTTQQTFDPMVMPPPFT-", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * : : : :::: . : : : :*: * : : *. : * *: . : * .**: . : : . * : *: :*. : . * * *:. :. :.:: *.****.. ** : ... : . :* * . .: ::**** .* : : * .* : .: . : : . * . : ::: :: * .* * ", "identical_positions": 35, "similar_positions": 74, "identity": "6.14%" }, { "cls_id": "homologset.agr.MGI:1891808", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A2RUW1-1", "uniprot_id": "TOLIP_RAT", "id": "A2RUW1-1", "name": "Toll-interacting protein", "aln": "-------------------MATTVSTQRGPVYIGELP-QDFLRITPTQQQQQIQLDAQAAQQLQYG--------GAVGTVGRLSITVVQAKLAKNYG----MTRMDPYCRLRLGYAVYETPTAHNGAKNPRWNKVIQCTVPPGVDSFYLEI----------------------FDERAFSMDDRIAWTHITIPESLKQ---------------------GQVEDEWYSLSGRQGDDKEGMINLVMSYTSLPAAMMMPPQPVVLMPTVYQQG--------------VGYVPIAGMPAVCSPGMVPMAMPPPA-VAPQPR--------CNEEDLKAIQDMFPNMDREVIRS------VLEAQRGNKD-------------AAINSLLQMGEES--------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9QZ06-1", "uniprot_id": "TOLIP_MOUSE", "id": "Q9QZ06-1", "name": "Toll-interacting protein", "aln": "-------------------MATTVSTQRGPVYIGELP-QDFLRITPTQQQQQIQLDAQAAQQLQYG--------GTVGTVGRLSITVVQAKLAKNYG----MTRMDPYCRLRLGYAVYETPTAHNGAKNPRWNKVIQCTVPPGVDSFYLEI----------------------FDERAFSMDDRIAWTHITIPESLKQ---------------------GQVEDEWYSLSGRQGDDKEGMINLVMSYTSLPAAMMMPPQPVVLMPTVYQQG--------------VGYVPIAGMPAVCSPGMVPMAMPPPA-VAPQPR--------CNEEDLKAIQDMFPNMDREVIRS------VLEAQRGNKD-------------AAINSLLQMGEES--------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9H0E2-1", "uniprot_id": "TOLIP_HUMAN", "id": "Q9H0E2-1", "name": "Toll-interacting protein", "aln": "-------------------MATTVSTQRGPVYIGELP-QDFLRITPTQQQRQVQLDAQAAQQLQYG--------GAVGTVGRLNITVVQAKLAKNYG----MTRMDPYCRLRLGYAVYETPTAHNGAKNPRWNKVIHCTVPPGVDSFYLEI----------------------FDERAFSMDDRIAWTHITIPESLRQ---------------------GKVEDKWYSLSGRQGDDKEGMINLVMSYALLPAAMVMPPQPVVLMPTVYQQG--------------VGYVPITGMPAVCSPGMVPVALPPAA-VNAQPR--------CSEEDLKAIQDMFPNMDQEVIRS------VLEAQRGNKD-------------AAINSLLQMGEEP--------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q7ZV43-1", "uniprot_id": "TOLIP_DANRE", "id": "Q7ZV43-1", "name": "Toll-interacting protein", "aln": "-------------------MATTISTQRGQVYIGELP-QDFLRIMPTQQQQQVQLDAQAARQLQYG--------GSLGTAGRLSITVVQAKLAKNYG----MTRMDPYCRIRLGYAVYETPTAHNGAKNPRWNKVIQCTVPPGVDSFYLEI----------------------FDERAFSMDDRIAWTHVTIPENLRE---------------------GTVVDEWYSLSGRQGDDKEGMINLVMSFATIPAGMMMQPQPVVLMPTVYQQG--------------VGYVPIAGVPGMYNQGVVPMGMPAAAPVASQSAP-------CSEEDLKALQDMFPNLDKEVIRT------VLEAQQGNKD-------------AAINSLLQMAEEL--------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q05610-1", "uniprot_id": "DON1_YEAST", "id": "Q05610-1", "name": "Donuts protein 1", "aln": "MGKKNRKGKENNAAKT---SFLKVENIKNTNSGLELPSQDYTNVEEKESSPKTDFPLITKEHVNTK--------TDSNILDYPTIGDLVSSVEKLCV----LKELKIAFPEVDDTLIKAILIASQGVLEPAFNSLLYYSSPEENTDFALPMKPI-------SVEDYSKINVSEILQREIFDDIEDEFSGQGINGSMVI---------------------SKIESELSSLAEHIGNISTPGSNREVAESTRNVAVAEGHNTILSNEDSILKGKEKGKEEEKEKGEEKGVNSLKGAAVKVVAKSLKNNRIPVTVKRNEPSNNLFDVLNCDESEEEEEQDVETNTSNQERKNQGGNTEVPEAQRDSADRLPAKDDGGYKSAFGTDSCGLFAADAKDEKKQVHPSRQELSFT---", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "Q08412-1", "uniprot_id": "CUE5_YEAST", "id": "Q08412-1", "name": "Ubiquitin-binding protein CUE5", "aln": "MEEKEGIKDSSLLEKSNVPESINEDISKTTDVDLNSDGKKDNDTSAKDGTPKVEEKVNKSSGIDEDEVVTPAEDAKEEEEEHPPLPARRKSEEEPSKENPILQELKDAFPNLEEKYIKAVIIASQGVLSPAFNALLFLSDPESGKDIELPTQPVRKNPEAPARRRQTQLEQDELLARQLDEQFNSSHSRRRNRDRATRSMHEQRRRRHNPNEREQHHEDSEEEDSWSQFVEKDLPELTDRAGRSLQDTANKVSNWISDAYRRNFASGNEQNDNQHGHQDQQEWEPEIVDLSQGGKNSRPQQPERRRFNSFGVQVGDDSLESHGITLHNEDGFEDDEDVPPQLPTRTKSGESTGKVVAETTYIDTPDTETKKKWQPLPPEPLDTTPTKVNAVSRNKKNPDEDEFLINSDDEM", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . . : : :. .: : : :: : . : : .:. : * :*. .* :* :: : * .: * : * : : . : . .. .: : . : : .. :. * . : .*. : :*: .: . * *: . :: ", "identical_positions": 12, "similar_positions": 61, "identity": "2.92%" }, { "cls_id": "homologset.agr.MGI:1891823", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q5PQQ2-1", "uniprot_id": "WBP11_RAT", "id": "Q5PQQ2-1", "name": "WW domain-binding protein 11", "aln": "MGRRSTSSTKSGKFMNPTDQARKEARKRELKKNKKQRMMVRAAVLKMKDPKQIIRDMEKLDEMEFNPVQQPQLNEKVLKDKRKKLRETFERILRLYEKENPDIYKELRKLEVEYEQKRAQLSQYFDAVKNAQHVEVESIPLPDMPHAPSNILIQDIPLPGAQPPSILKKTSAYGPPTRAVSILPLLGHGVPRLPPGRKPPGPPPGPPPPQVLQMYGRKVGFALDLPPRRRDEDMLYSPELAQRGHDDDMSSTSEDDGYPEDMDQDKHDDSTEDSDTDRSDAESDGDEFGHRDDSERDNTEEKKSGLSVRFADMPGKSRKKK--KNMKELTPLQAMMLRMAGQEIPEEGREVEEFSEEEDDDDSEDSEAEKPSQKQHKEDSHADGSSAASSQQQAPPQAVPPSQIQAPPMPGPPPLGPPPAPPLRPPGPPTGLPPGPPPGAPPFLRPPGMP-GIRGPLPRLLPPGPPPGRPPGPPPGPPPGLPPGPPPRGPPPRLPPPAPPGIPPPRPGMMRPPLVPPLGPAPPGLFPPAPLPNPGVLSAPPSLIQRPKADDAS------------------------AATIEKKAT-------------ATISAKPQITNPKAEVTRFVPTALRVRRENKGATAVPQR-RSEEDSAVPVAKAAPRSGPSVPVSVQTKDDVYEAFMKEMEGLL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q923D5-1", "uniprot_id": "WBP11_MOUSE", "id": "Q923D5-1", "name": "WW domain-binding protein 11", "aln": "MGRRSTSSTKSGKFMNPTDQARKEARKRELKKNKKQRMMVRAAVLKMKDPKQIIRDMEKLDEMEFNPVQQPQLNEKVLKDKRKKLRETFERILRLYEKENPDIYKELRKLEVEYEQKRAQLSQYFDAVKNAQHVEVESIPLPDMPHAPSNILIQDIPLPGAQPPSILKKTSAYGPPARAVSILPLLGHGVPRLPPGRKPPGPPPGPPPPQVLQMYGRKVGFALDLPPRRRDEDMLYSPELAQRGHDDDMSSTSEDDGYPEDMDQDKHDDSTEDSDTDRSDAESDGDEFGHREDSERDNTEEKKSGLSVRFADMPGKSRKKK--KNMKELTPLQAMMLRMAGQEIPEEGREVEEFSEEEDADDSDDSEAEKQSQKQHKDDGHSDSTAAASSQQQAPPQSAPASQIQAPPMPGPPPLGPPPAPPLRPPGPPTGLPPGPPPGAPPFLRPPGMP-GIRGPLPRLLPPGPPPGRPPGPPPGPPPGLPPGPPPRGPPPRLPPPAPPGIPPPRPGMMRPPLVPPLGPAPPGLFPPAPLPNPGVLSAPPSLIQRPKADDAS------------------------AATIEKKAT-------------ATISAKPQITNPKAEVTRFVPTALRVRRENKGATAVPQR-RSEDDSAVPVAKAAPRSGPSVAVSVQTKDDVYEAFMKEMEGLL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9Y2W2-1", "uniprot_id": "WBP11_HUMAN", "id": "Q9Y2W2-1", "name": "WW domain-binding protein 11", "aln": "MGRRSTSSTKSGKFMNPTDQARKEARKRELKKNKKQRMMVRAAVLKMKDPKQIIRDMEKLDEMEFNPVQQPQLNEKVLKDKRKKLRETFERILRLYEKENPDIYKELRKLEVEYEQKRAQLSQYFDAVKNAQHVEVESIPLPDMPHAPSNILIQDIPLPGAQPPSILKKTSAYGPPTRAVSILPLLGHGVPRLPPGRKPPGPPPGPPPPQVVQMYGRKVGFALDLPPRRRDEDMLYSPELAQRGHDDDVSSTSEDDGYPEDMDQDKHDDSTDDSDTDKSDGESDGDEFVHRDNGERDNNEEKKSGLSVRFADMPGKSRKKK--KNMKELTPLQAMMLRMAGQEIPEEGREVEEFSEDDDEDDSDDSEAEKQSQKQHKEESHSDGTSTASSQQQAPPQSVPPSQIQAPPMPGPPPLGPPPAPPLRPPGPPTGLPPGPPPGAPPFLRPPGMP-GLRGPLPRLLPPGPPPGRPPGPPPGPPPGLPPGPPPRGPPPRLPPPAPPGIPPPRPGMMRPPLVPPLGPAPPGLFPPAPLPNPGVLSAPPNLIQRPKADDTS------------------------AATIEKKAT-------------ATISAKPQITNPKAEITRFVPTALRVRRENKGATAAPQR-KSEDDSAVPLAKAAPKSGPSVPVSVQTKDDVYEAFMKEMEGLL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6P0D5-1", "uniprot_id": "WBP11_DANRE", "id": "Q6P0D5-1", "name": "WW domain-binding protein 11", "aln": "MGRRSTSSTKSGKFMNPTDQARKEARKRELKKNKKQRMMVRAAVLKMKDPRQIIRDMEKLDEMEFNPVQQPLLNEKVLRDKRKKLRETFERIVRLYERENPETYKELRKLELEYETKRGQLSLYFDSVKNAESVEVDSIPLPEMPHAPSSILIQDIPLPGAQPPSILKKSSALG---KASSLSAAALAGVPRLPAGRKPPGPPPGPPPPQILQLYG---------NTRRTEASAGSDTEMMDGGRDSDSKSEADEE-----------SDSQEDSSAEREDSDR-----GERDE-ERER-ADKHTGRSVRFADMPSPNKKKRRVVKTKSITPLQAMMLRMAGQSVPEE----EEEDEEEEYSESEDSEAEDQASTDAPQPLVNPRLPVPSAPMAAQQ---PPSLMQAPPITGPPPLGPPPAPPMRPPGPPSGPPPGPPPGAPPFLRPPGLPSALRGPMPRLLPPGPPPGRPPGPPPGPPPGLPPGPPPRGPPPRLPPPAPPGMPPPPP---PPRAGPPRMAPPLSLFPPP--LNPNVLSAPPSIVPRQKSPAASSNEGAPSGSALQMPPPPGTTANPLAPTIEKRATVAGSGGASAQGGGATISAKPQIINPKAEVTRFVPTALRVRRDRAGGTGRREEERPPANQQTPAHQAPPIAHAPTPPNLKTKDQVYEAFMREMEGLL", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "O76861-1", "uniprot_id": "O76861_DROME", "id": "O76861-1", "name": "Wbp11/ELF5/Saf1 N-terminal domain-containing protein", "aln": "MGRRSINTTKSGKYMNPTDQARKEARKKELKKNKKQRQMVRAAVLKNKDPSQILEEMEKIDEMEYNVLQPSPLNEKVLRDKRKKLKETFDRVMRLYHNDEPEHWADLKRKEVEYEKKRLKKQQYYESVKHAQSVQIDEIPLPAPVSAVS---------GGSTETTGGSVVAGFG---ASVVIRLPPPPMTMALPP--YAPGAPPGVSRNSDLASEA---------QVEKSKENEQKDWLGVPPGPPPDLFAFSELN-----------SDAEGNTDYDGEGEEEEPEPLKKGKDKEKDKNSEATEPNNQNIDDF---------------MKEMEHVHKRKHRKLAAKE----DEADKKREEDDGKDIDKIEERTSDSDKRTASSTDDEDDDDQDEDEN--MPEVPTKPASVKSSTATPAPAPPTAPTLPTIPLPPASSVPAPPQL--PHLP-----PIPNLGPPGIMYRPPPMRPPHPGSGFGIRMPP-GPPP--GPRAPHGLGPIPRMGIRMPPGPPPG-------------------LPPRLAHHNKQGGGAG-----------------------APKESAKGV-------------ATITAKPQIRNLSADVTRFVPSTLRVKREDQRRTARPRHAANDGHHAHSEAHSKP----------PTKDDAYLQFMNEMQGLL", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "***** .:*****:*************:********* ******** *** **:.:***:****:* :* . ******:******:***:*::***..::*: : :*:: *:*** ** : . *:::**:*: *:::.**** * * *: .: . :. * : : . **. .**.*** . . : . .: . . . * * : :: : .*: ::. : .. : . .: *::. : . .: *: :. :: : * : .:* :* .:. : .:..* : . .: . . .. *. ... *.**** *. *. **... *** * * :* *:*.* *** ** ** * .*: ** **** * ** *: * ** ** : : * : *.. . :.. ***:***** * .*::*****::***:*: *. .. . . :: * ***:.* **.**:***", "identical_positions": 187, "similar_positions": 151, "identity": "27.42%" }, { "cls_id": "homologset.agr.MGI:1891824", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "E9PST5-1", "uniprot_id": "E9PST5_RAT", "id": "E9PST5-1", "name": "Apoptotic chromatin condensation inducer in the nucleus", "aln": "MWRRKRPNSSGGTRGILSGNRGVDYGSGRGQFGTFEGRWRKLPKMPEAVGTDPSTSRKMAELEEVTLDGKPLQALRVTDLKAALEQRGLAKSGQKSALVKRLKGALMLENLQKHSTPHAAFQPNSQIGEEMSQNSFIKQYLEKQQELLRQRLEREAREAAELEEASAESEDEMTHP------EGVASLLPPDFQSSLDRP----------ELELSTHSPRKSSSFSEEKGES-------------------DDEKPRKGERR------------------------------------------SSRVRQAR-AKLPE-------------------------------YSQAAEEEEDQETPSRNLRVRADRN-------------LKVEEEEEEEEEE--DDEEEEEEVDEGQKSREAEAPILKQFEDEDGEEMTRAKPEKVVDEKPPIIRSQE---KDELEKGGRVTRSQEEARRSHLARQQQEKETQIVS-LPQEENEVKSSQGLEEKSQSPSLPPLPEDLEKAPVVLQPEQIVSEEETPPPLLTKEASSPPT----------------------------HMQLQDEEEVEPAEGPAPPVLIQLSPPGTDAGTREPIVS---------------------------------------------------------------------------------------------------------------------------------PHTVQLLRGLSPLSSTADTKAESPAERVSEESVLPLAQ-RSILPEHSAQKG-----------------------AESEREKSAPLLPLTREELAPAKGITEESVKKQSLEQEEGRRASHTLFPDHS----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------LKPSADSSSSR----------SSSPSSSSSRSRSRSPDSSASRSQSSPRSKQREVSQARVHANPHDRAKMGS--------RSTSESRSRSRSRSRSASSGSRKSLSPGVSRDGNTT-------YTETKDPSCGQEAAAPSVPQLQVLEPKEKAPTCSASVRGRHMSQPEPE--QKHVIQRLQPEQESPKKCEAEEAEPPAATQPQTSEPQLSQLPEAERTPHTAEEKEDVTMDTSEN----RPENEVPEPPVP------------------------IADQVSNDDRPEGSAEEEERK-------------------------ESSMPKSFKR-KISVVSATKGVQAGNSD-----TEGGQPGRKRRWGASTAATQKKP-SISITTESLKSLIPD-IKPLAGQEAVVDLHADDSRISEDETER---NGDDGTHDKGLKICRTVTQVVPAEGQENGQRE-------------EEEE-KEPEAEPPAPPQASVEAALPPP-VEHEVKKVTLGDTLTRRSISQQKSGVSITIDDPVRTAQVPSPPRGKISNIVHISNLVRPFTLGQLKELLGRTGTLVEEA-FWIDKIKSHCFVTYSTVEEAVATRTALHGVKWPQSNPKFLCADYAEQDELD----YHRGLLVD-RPSEAKTEEQGAPRPLHPPPPPPVQPPPHPRAEPREQER-----AVREQWAEREREMERRERTRSEREWDRDKVREGP-----------RSRSRSRDRRRKER---AKSKEKKSEKKEKAQEEPPAKLLDDLFRKTKAAPCIYWLPLTESQIVQKEAEQAERAKEREKRRKEREEEEQKEREKEAERERNRQLEREKRR-EHSRER--ERDRERERDRG---DRDRDRERDRDRGRERDRRDTKRHSRSRSRSTPVRD----RGGRR", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9JIX8-1", "uniprot_id": "ACINU_MOUSE", "id": "Q9JIX8-1", "name": "Apoptotic chromatin condensation inducer in the nucleus", "aln": "MWGRKRPNSSGETRGILSGNRGVDYGSGRGQSGPFEGRWRKLPKMPEAVGTDPSTSRKMAELEEVTLDGKPLQALRVTDLKAALEQRGLAKSGQKSALVKRLKGALMLENLQKHSTPHAAFQPNSQIGEEMSQNSFIKQYLEKQQELLRQRLEREAREAAELEEASAESEDEMTHP------EGVASLLPPDFQSSLNRP----------ELELSTHSPRKSSSFSEEKGES-------------------DDEKPRKGERR------------------------------------------SSRVRQAK-SKLPE-------------------------------YSQTAEEEEDQETPSRNLRVRADRN-------------LKIEEEEEEEEEEEDDDDEEEEEVDEAQKSREAEAPTLKQFEDEEGEERTRAKPEKVVDEKPLNIRSQE---KGELEKGGRVTRSQEEARRSHLARQQQEKETQIVS-LPQEENEVKSSQSLEEKSQSPSPPPLPEDLEKAPVVLQPEQIVSEEETPPPLLTKEASSPPT----------------------------HIQLQ--EEMEPVEGPAPPVLIQLSPPNTDAGAREPLAS---------------------------------------------------------------------------------------------------------------------------------PHPAQLLRSLSPLSGTTDTKAESPAGRVSDESVLPLAQ-KSSLPECSTQKG-----------------------VESEREKSAP-LPLTVEEFAPAKGITEEPMKKQSLEQKEGRRASHALFPEHS----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------GKQSADSSSSR----------SSSPSSSSSPSRSPSPDSVASRPQSSPGSKQRDGAQARVHANPHERPKMGS--------RSTSESRSRSRSRSRSASSSSRKSLSPGVSRDSNTS-------YTETKDPSCGQEAAAPSGPQLQVLEPKEKAPTFSASVRGRHLSHPEPE--QQHVIQRLQPEQGSPKKCEAEEAEPPAATQPQTSETQISHLLESERTHHTVEEKEEVTMDTSEN----RPENEVPEPPLP------------------------VADQVSNDERPEGGAEEEEKK-------------------------ESSMPKSFKR-KISVVSATKGVQAGNSD-----TEGGQPGRKRRWGASTAATQKKP-SISITTESLKSLIPD-IKPLAGQEAVVDLHADDSRISEDETER---NGDDGTHDKGLKICRTVTQVVPAEGQENGQRE-------------EEEE-KEPEAELPAPPQVSVEVALPPP-VEHEVKKVTLGDTLTRRSISQQKSGVSITIDDPVRTAQVPSPPRGKISNIVHISNLVRPFTLGQLKELLGRTGTLVEEA-FWIDKIKSHCFVTYSTVEEAVATRTALHGVKWPQSNPKFLCADYAEQDELD----YHRGLLVD-RPSETKAEEQGAPRPLHPPPPPPVQPPPHPRAEQREQER-----AVREQWAEREREMERRERTRSEREWDRDKVREGP-----------RSRSRSRDRRRKER---AKSKEKKSEKKEKAQEEPPAKLLDDLFRKTKAAPCIYWLPLTESQIVQKEAEQAERAKEREKRRKEREEEEQKEREKEAERERNRQLEREKRR-EHSRER--ERDRERERDRG---DRERERERDRDRGRERDRRDTKRHSRSRSRSTPVRD----RGGRR", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9UKV3-1", "uniprot_id": "ACINU_HUMAN", "id": "Q9UKV3-1", "name": "Apoptotic chromatin condensation inducer in the nucleus", "aln": "MWRRKHPRTSGGTRGVLSGNRGVEYGSGRGHLGTFEGRWRKLPKMPEAVGTDPSTSRKMAELEEVTLDGKPLQALRVTDLKAALEQRGLAKSGQKSALVKRLKGALMLENLQKHSTPHAAFQPNSQIGEEMSQNSFIKQYLEKQQELLRQRLEREAREAAELEEASAESEDEMIHP------EGVASLLPPDFQSSLERP----------ELELSRHSPRKSSSISEEKGDS-------------------DDEKPRKGERR------------------------------------------SSRVRQARAAKLSE-------------------------------GSQPAEEEEDQETPSRNLRVRADRN-------------LKTEEEEEEEEEEE-EDDEEEEGDDEGQKSR--EAPILKEFK-EEGEEIPRVKPEEMMDERP-KTRSQE---QEVLERGGRFTRSQEEARKSHLARQQQEKEMKTTSPLEEEEREIKSSQGLKEKSKSPSPPRLTEDRKKASLVALPEQTASEEETPPPLLTKEASSPPP----------------------------HPQLHSEEEIEPMEGPAPAVLIQLSPPNTDADTRELLVS---------------------------------------------------------------------------------------------------------------------------------QHTVQLVGGLSPLSSPSDTKAESPAEKVPEESVLPLVQ-KSTLADYSAQKD-----------------------LEPESDRSAQPLPLKIEELALAKGITEECLKQPSLEQKEGRRASHTLLPSHR----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------LKQSADSSSSR----------SSSSSSSSSRSRSRSPDSSGSRSHSPLRSKQRDVAQARTHANPRGRPKMGS--------RSTSESRSRSRSRSRSASSNSRKSLSPGVSRDSSTS-------YTETKDPSSGQEVATPPVPQLQVCEPKERTSTSSSSVQARRLSQPESA--EKHVTQRLQPERGSPKKCEAEEAEPPAATQPQTSETQTSHLPESERIHHTVEEKEEVTMDTSEN----RPENDVPEPPMP------------------------IADQVSNDDRPEGSVEDEEKK-------------------------ESSLPKSFKR-KISVVSATKGVPAGNSD-----TEGGQPGRKRRWGASTATTQKKP-SISITTESLKSLIPD-IKPLAGQEAVVDLHADDSRISEDETER---NGDDGTHDKGLKICRTVTQVVPAEGQENGQRE-------------EEEEEKEPEAEPPVPPQVSVEVALPPP-AEHEVKKVTLGDTLTRRSISQQKSGVSITIDDPVRTAQVPSPPRGKISNIVHISNLVRPFTLGQLKELLGRTGTLVEEA-FWIDKIKSHCFVTYSTVEEAVATRTALHGVKWPQSNPKFLCADYAEQDELD----YHRGLLVD-RPSETKTEEQGIPRPLHPPPPPPVQPPQHPRAEQREQER-----AVREQWAEREREMERRERTRSEREWDRDKVREGP-----------RSRSRSRDRRRKER---AKSKEKKSEKKEKAQEEPPAKLLDDLFRKTKAAPCIYWLPLTDSQIVQKEAERAERAKEREKRRKEQEEEEQKEREKEAERERNRQLEREKRR-EHSRERDRERERERERDRG---DRDRDRERDRERGRERDRRDTKRHSRSRSRSTPVRD----RGGRR", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F1Q511-1", "uniprot_id": "F1Q511_DANRE", "id": "F1Q511-1", "name": "", "aln": "----------------------------------------------------------MAELEDVTLDGKPLHSLRVADLKTALEERGLAKSGQKNALIKRLKGALMLENLQRSSTCHSGIQPNSQIGEEMSQNSFIKQYLAKQQELLRQRLEREAREATEADESQSPAGPEEDD------NDSTSFLLEKHHIAHAHLSAGGGLPQ---DPGLVGSQKLDTGPVPVSQES--------------------SDSKAG-------------------------------------------------RIWHPSFP--------------------------------------SGHEDVATPSPPRAVASLSVR------------------VVGQPERQGLPPRSQEREGTAPVEAGPAHSMLQLSRSARAAG--------GAQVDSDD----------DDDEEDDDDSEDDDEWGPASHGKKNVRAPPARAPPAAAPQRSRRKLQPPQHIPPQLQP-------------VLQPPLQL-RQPTPPPSPPPELSFPLP----------------------------DTPKQSPHDQDEPAGLAEAAVPGPGMVSPPSLTRQ------------------------------------------------------------------------------------------------------------------------------------ESSSSSRSSSPEPPSTRKPGPLSLLVRKMESEGVFGSAQNIEVKGEGDMEVE-----------------------EQEHSEAAVQDSTRELSRTDVSSSVSTMPPDQQGIQDSELEKGEDE----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------PKPSEETQ-------------NEKVDETSVPLCSTSTTTRSSRRQRIFSEVPPPESLMSPS-----KPEQLS-----MLTSISKGS-------EDSPMETEEFTTTPASKHKEDKE--------LKGLNNEAPEESPKPADENKKALT----SPHATSEEEKMDKTRDRSK---KDKRRSSTSSQSSSSDADSESSSSHSSSSPSRDKSSPTS-KTKDVEEKGRKGAEEKKAQSSRE----VKQEALSEPTG------------------------QVAMELEGLSHSESAVQQSDHQGADSSDSRP---------------EESSAAKSFAARKISLSS---KTEIASSE----SEPVGGASRKRRWGSSTAVTAKKP-SISITTESLKTLIPD-IKP--LQEAVVDLHPDEGRLSVDEDSSGPREREEPEEDQGLKIRRTVTQIVPSDGHENGQKEMDEKDEEEDEDDEEEEQKHSGEEKEKPRKQESSP-DASVETPECDSQKVTPSDSLVRRSISQQKSGVSITIDDPIRTGRQLSPPRGKTSNIIHVLHLVRPFTLGQLKLLLNRTGTMVEEG-FWIDKIKSHCYVTYSTVEEAVATREALHGVKWPASNPKVLRVDFSDQDELD----FHKGLISGERAGVGHDPKASGPSSRPPAAHPPIPPPNHEKEKERERDRDGGSSAVRDQWAERERAMERRERTRSEREWDRDKVKDFG-----REERDRTRRSRSRERRRRER---GKSKEKRTEKKEK-PEEPPVKLLDDLFHKTKAAPCIYWLPLTDEQATQRDQERADRIKEREKRRKEIFEEEDKKRK-EREQERAKGRDRVGGNTAETRAGVPRRSTEGERDRGKGGERERGREADKRKDAQRGQRDSKTTTAAGNRRSQSHN-STSRDRRH", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8M2BIJ9-1", "uniprot_id": "A0A8M2BIJ9_DANRE", "id": "A0A8M2BIJ9-1", "name": "", "aln": "----------------------------------------------------------MADLEDVTLDGRPLHSLRVADLKAALEERGLPKSGQKNALVKRLKGALMLENLQKTSTPHIGLQPNSRIGEEMSQNSFIKQYLAKQQELLRQRLEKEAREAAETDGTDRGDHTESNDNIHAASNQDVASSLVDQNQGSAAVAGGFGVTESESEKEMPGQPSLSTAAHSRPRASSVRLRGKGEPTSSHVPAESDDDSEAGDDEEEEEWNARPQRSRRAQPPKSQPVRTRSSGSQQQQQPPPQHIPLLSQQLRHPTPPPSPPPELSFPLPDTPKQSPPSPGESPSRQRISSSSSSGSSSSDSRSSSPEPASDTTERRPGPLTLLARKMASERACSGAGKRDREGVDLQRSHQEGVVSAITHTANAASVLSHPSSVISNQGVSVVRAAVMEASDGIKQDEGVLWEQEQERLKALEKEEEEREKALEKERAQALERKRLEAASKREKERALQREREEKERLEREQALERERALEQERLERERQE-KERVEKERQEKEQALERERLKQERLEKERQEREEALERERLERERLEKERQEREEALEKERLERERLEKERREKEAALERERLEKERLEKEKKEKEAALERERLEKERIEKEKREKEEALERERLEKERLEKEKREKEEAQERERLKKERLEKEKKEALEKERLEKERQEKEAVERERLEKERLEKEKREKEAALERERLEKERIEKEKREKEEALERERLEKERLEKEKREKEEALERERLEKERLEKERQEKEVLERERLEKERLEKERKEQEEALERERLEKEKLEKEKQEQALERERLEKERLEKERKEQEKALERERLEKEKLEKEKQEQALERERLEKERLEKERKEQETLEREKLEKLEKEKQEREQALERERLEKEHIEKEKREKEALERERLEKERLEKERNEREQAIERERQEKEEREREETLEKERKEQERLEKERALEKEREAALELKKQEQERLEKEKALEEERLQKEQALQHEREAERKKEEERKQALEKQKEEQERALKEEKREKLLKQKSVEEEKGKALKHEKEEEKESHLHPRKCGRDSGEFSHPVVHPGSPKSSPKKSDESEPGENPSISKDVQSSEPVPQQSPTLATPLSHQSSSKKSRFLRDAPVMAPLPSSVGSVLKRPRTFSDSPQPRAPSIPTDSKSKEPVQEDAAQAPQTSVLTSGPHDLERKTPEVAVKQSVPQENIQTSEDSEASKDTKHKTLTGVEDVKKSSTPEEEKKRGRAREKKVEKKERKSSSSSNTSSSDSDSGSSSSRSSSSSSSSSSSSSSEEEKSCSASGGRRSEEVKRDSSSQPTEKVCQTVAEKPPAPQRKKRVFTEKEEKDVNNEVIQNKKPCLDLQDGKETKEDIEEDADTNKDTTRSEVKEAVMSEPEKVSESGEESTMAKTFSARRISISSSKASPGVGSSEGEAETASSAGAGRKRRWGSSTAVTAKKP-SISITTDSLKSLIPD-IKPSVGQEAVLDLHPEEMHLSGEEEGG---ERS----DHDLKIRRTVTQIVPSETQENGQKESKRSDHEDEEETTEERDRISPEEKTEGSLQVSMETEPSSPGRDVDMKTVSPSDTRIRRSISQQKSGVSITIDDPVRTAKQPSPPRGKLSNIVHVCNLVRPFTLGQLKELLNRTGTVVEES-FWIDKIKSHCYVTYSSAEEAMATRTALHGVKWPQSNPKFLSVDFCTQDELD----FHRGLGP---AGEKPPEDARGAAAAGPGRPMPVPLLPE-----------------RDQWAEREREMERRERARAEREWDRDKVRDFSKPGEDREPGARRSRSRDRERRRKER---GKSKERKADKKEKGPEEPPAKLLDDLFRKTKAAPCIYWLPLTEEQAAQRAAARAERMREREKRIKEMEEEEGKKRE-EERRERMKPSGTAGG------EGERGRDRERERDRG----REREREGDKRK---EGYRRPGVNSASGSRRSRSRSDPPPRDRRR", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VJ12-1", "uniprot_id": "Q9VJ12_DROME", "id": "Q9VJ12-1", "name": "", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MRRRSERKKSSSPAPVPVAVARRS-----------------------------------------------------------------------------------------RRSRKVSENEKTEVETPVVAQNNEAECPKVPPASQEINEAR---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ASSEERAGSGASPVRRSRGSRTTPRKRTESKGG-----------------------------------------------------DKKVDTIPEEEPENGKDVEKDAVEEEK-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------TVAPPAANESESEDRAKTE-------------------------------------------------DQQAQDDESCAEPAVVKDDDVE----------KEDLKPQQEVPTSTDDDTKQSEPEQEVKVPSPSSKDEEHLKTTSD--VLDIQTEEVDERDEEASAPAERRETKKRHKEQIKEQQPAEEEEHKENHKQIDENPEQIHDEPAD-----LSNDKHDPCLN-----------------------------------------------------------------------------------SSATNTTGAPVLQQQ---------RSVRKRKWLTNKKSSDRTPPVLAISTDSLKNIIADVVQPVPLSDVQLESSSEEEGLVTSDRDS----------------ERSASPAPPSEASKDRDNK------------------GNTANTCDTTAEASADNEGAGAAPPAAADTVSAQVSLSKATVSTAAP----------HIVRDPSPARNRASHVLYITNLVRPFTVLQLKGLLARTGKIVEEDGFWIDRIKSKCYVAYSTEDEAIETRHALHGVRWPVSNPKCLNVDFGSRTDMDRAILSTKDEAPRYGQENTRDNQQSGNAWSRLEPSDKKPARPVREWDVGKKEPSDHDKHSNDRRRDSKDRLDSRSRDAERAGQERKRSRDRE------------GRGRDRERERLDRNAHARSRSGSPASKTKKENEPPIRLLDDLFRKTKGTPCIYWLPLTPEAIAEKEAFRQKRIEEHKLRIKER-EERQKEREKDRDRQRETR-----------------RNRSNERRRS------RSRERERRRY--------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . :* * . .:: : . . . . . : .: . .: ::..: : . :: . .. : . :: . . : :. . : . .. . .. : .. . . .. . : . : : . : . .* * : ..: . ***:* :.. : :.* ::*:*:***.:*.* ::* .:. :: .:: : .: *:.: *:: :: :.: . : * . ..*: : : ::* . : : **.*.: *::::: :******: *** ** ***.:*** ****:***:*:*:**: :**: ** *****:** **** * .*: : ::* :. . .:: : : :: *.* . :*.: :: *.*.*:*.* :* .:*:. . .* * :*** :******:***.:********* . .:: : .* .*:: * ** **. *:*: : ::* *. . ** *. * ** :: : ", "identical_positions": 122, "similar_positions": 197, "identity": "6.04%" }, { "cls_id": "homologset.agr.MGI:1891825", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZYY8-1", "uniprot_id": "D3ZYY8_RAT", "id": "D3ZYY8-1", "name": "Mannosyltransferase", "aln": "---------MEPETRDHSTAFRNLHS-SSGEMKLRKRKSTQYVIAQEKRSRRRD-LLGENTYLVLFTIALRIFNCFLVQTSFVPDEYWQSLEVAHHMVFGYGYLTWEWTERLRGYTYPLIFASIYKILHLLGKDSVQLLIWI--------------------------------------------PRLGQALLSAVADLRLYSLTKQLENQ------------------EVARWVFFCQLCSWFTWYCCTRTLTNTMETALTAVALFYYPLEGSRSKNSVKY---SLLVALACVVRPTALIPWVP----LLFRHLYQE-QRKLHLTLHHFLPVGFITFSLSLIIDRIFFGQWTLVQFNFLKFNVLQNLGTFYGSHPWHWYFSQGFPVVLGTHLPFFIHGCFLAPRR----------LNILLLAVLWTLLVYSMLGHKEFRFIYPVLPFCMVFCGYSLAHLK--AWRK-----AALSFLLLSNVLLALYTGLVHQRGTLDVMSHIQKVCPRGPDP--APASVFIMMPCHSTPYYSHVH-----------CPLSMRFLQCPPDLTGKTQYLDEADTFYLNPLGWLQQEFHSN-------------VSLPTHLVTFNVLEKEIH-AFLTSGNYERTATFFHTHWPER----------------------------RTGSHIHVYERRLTSR---VSTGGN----------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9JJQ0-1", "uniprot_id": "PIGB_MOUSE", "id": "Q9JJQ0-1", "name": "GPI alpha-1,2-mannosyltransferase 3", "aln": "---------MESQAADYNPASRNLHG-SSGEMKLRRRKSRQYVSAQEKRSPRRG-LLGENTYLVLFTIALRILNCFLVQTSFVPDEYWQSLEVAHRMVFSYGYLTWEWTERLRGYTYPLIFASIYKVLHLLGKDSVQFLIWI--------------------------------------------PRLGQALLSAVADIRLYSLLKQLENQ------------------EVAQWVFLCQLCSWFTWYCCTRTLTNTMETSLTALALFYYPLEGSRSVNSVKY---SLLVALACVVRPTALIPWVP----LLFRHFYQE-QRKLHLTLHHFLPVGFITFSLSLIIDRIFFGQWTLVQLNFLKFNVLQNLGTFYGSHPWHWYLSQGFPVVLGTHLPFFIHGCFLAPRR----------LHILLLTVLWTLLVYSMLGHKEFRFIYPVLPFCMVFCGYSLAHLK--TWRK-----AALSFLLLSNVPLAFYTGLVHQRGTLDVMNHIQKVCPRGPDP--ASASVFIMMPCHSTPYYSHVH-----------CPLSMRFLQCPPDLTGKTQYLDEADMFYLNPLRWLQQEFHSN-------------ASLPTHLVTFNVLEKEIN-TFLTSGNYERAATFFHTHWPER----------------------------RTGSHIHVYERRLPGR---VNTGGN----------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q92521-1", "uniprot_id": "PIGB_HUMAN", "id": "Q92521-1", "name": "GPI alpha-1,2-mannosyltransferase 3", "aln": "MRRPLSKCGMEPGGGDASLTLHGLQNRSHGKIKLRKRKSTLYFNTQEKSARRRGDLLGENIYLLLFTIALRILNCFLVQTSFVPDEYWQSLEVSHHMVFNYGYLTWEWTERLRSYTYPLIFASIYKILHLLGKDSVQLLIWI--------------------------------------------PRLAQALLSAVADVRLYSLMKQLENQ------------------EVARWVFFCQLCSWFTWYCCTRTLTNTMETVLTIIALFYYPLEGSKSMNSVKY---SSLVALAFIIRPTAVILWTP----LLFRHFCQE-PRKLDLILHHFLPVGFVTLSLSLMIDRIFFGQWTLVQFNFLKFNVLQNWGTFYGSHPWHWYFSQGFPVILGTHLPFFIHGCYLAPKR----------YRILLVTVLWTLLVYSMLSHKEFRFIYPVLPFCMVFCGYSLTHLK--TWKK-----PALSFLFLSNLFLALYTGLVHQRGTLDVMSHIQKVCYNNPNK--SSASIFIMMPCHSTPYYSHVH-----------CPLPMRFLQCPPDLTGKSHYLDEADVFYLNPLNWLHREFHDD-------------ASLPTHLITFSILEEEIS-AFLISSNYKRTAVFFHTHLPEG----------------------------RIGSHIYVYERKLKGK---FNMKMKF---------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q7SXZ1-1", "uniprot_id": "PIGB_DANRE", "id": "Q7SXZ1-1", "name": "GPI alpha-1,2-mannosyltransferase 3", "aln": "---------MEKIRERFKQSKS-----SNESVRLRKRSSILYSTDDRK--LQTLKIFGIN--ITVFIVLVRLLNCVLVQTSFVPDEFWQSLEISHRMVFGYGYETWEWKEGIRGYSYPLLFALMYKLLQLISYDTVYLLVFV--------------------------------------------PRVFQALLAAYADVKLYKLILQWETP------------------DVAKWTCFCQLCSWFAWFCCSRTLTNTTETALTTLALCFYPLPGSKTHSSWKY---LTLVSLAVVIRPTALIVWFP----LIFYHFCTD-QDKLKLITHRYFPIGVLALGVSTLIDSFFYGKWIFVQWNFLKFNVLHNVGEFYGSHPWHWYWTQGLPVVIGPHLPLVLHGCLLSTRK----------HTILLLTIIWTTAVYSLLAHKEFRFIYPVLPFCMIFCGLSLAKLQ--AWRK-----AAAGALLLFNLCPALYTGLVHQRGALDVMHVLQPLCVSSQSP--NPPELLFLMPCHSTPLYSHLH-----------CPLKLRFLECPPDLTGRQDYMDEADVFFSDPLHWLNTSFPLR-------------STLPSHLVLFDSLQKEIS-SFLEENSFAKQAEIFHTHFPEG----------------------------RVGKNILIYSRRSEMK---INEGFIL---------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VZM5-1", "uniprot_id": "PIGB_DROME", "id": "Q9VZM5-1", "name": "GPI mannosyltransferase 3", "aln": "-------------------------------MKL--------------------------IYVFLLILAVRLASVFVVQTYYVPDEYWQSLEVAHKLTFGYGYLTWEWVQGIRSYVYPLLIAGLYKILALLQLDSAHLLVVL--------------------------------------------PRIVQALLSAYSDYRFFVWTGKR------------------------KWALFLILVPWFWFYTGSRTLANTLEASLTTIALSYFPWYG----ESTAY---LWPAAICCFLRPTAAVIWLP----LSLYHLRRSRQNVLELILKRFVLIGLLVAGLGIAIDTYWHGQLIVTPYEFLKYNIFNNIGSFYGSHPWHWYFSVGLPTVLGINTLPFIFGVMETVKKS----EKYPVSKQLLITIFLTLVVLSAVEHKEFRFVSPLLPLCLYVITDALSRWS--IRASSTMLWTTALVILVGNVMPAWYLSTVHQKGPIELMPKLREIAREYRDEREHQANILFLMPCHSTPYYSHIH-----------QNVTMRFLTCEPNLEKKEQYKDEADRFFEDPVHWINSHIPMHP-----------LTALPTHVVLFDPLAENIS-VFLRNYRLLHRIEHAEVTRLEGSQALVDQWSEALGAQSPNLASLLQNRQSRTGRSILVYQRLKKGEENAFNRGPDSGQHEPDVHDHPPLEDLVLANENENLFN", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P30777-1", "uniprot_id": "GPI10_YEAST", "id": "P30777-1", "name": "GPI mannosyltransferase 3", "aln": "--------------------------MAHEVHRIKPKLG--------------------RTQIFWVFLAFRVLNAVLTRTFFQADEFWQALEPAHWKAFKYGELTWEWKFGVRSYLFPMIFELTYRLVSLSSILLHYALLLLSTIGSDLLILLLPKYELSWQVAEDLKRLPFDVTRSFEYYGVIYAPKIVMAVLASIGEYYIVRFVQKLYLLTLDKRNEKEEEERRSGLSEITKFALLLSLTNFFNCFFITRTFINSFEMILTSIALYYWDWTGGQMIKESSFTKSLIFAFLACLQRPSSGLIWVIPSISLILNLVGKKQYHLLFITFSKVLRSFFLVFTANAIIDMYFYEKVTFPFFRFLKFNFTTPLSKFYGVAPWHFHFFQSLPIVLGASIPAFAFGLFFPLSKRSFPKKYLNPFFQVKLTILLNLLVYSTLPHKEFRFIFPLQPLFILISSFGLLRLDRDYWKRLSGLKSLLWLVPFVSVFIALLLDTFHESGSIEVMKFLHEEP--------EIDSLGFIMPCHSTPGQSYLHRSDIQDLWSITCNPPLHLLGDPEAYSKLETYMDESDHLYDDISAFIYKNFPPPFRKDLRSPGKTYSHEWPTYLVVFEHMENAFLKDFLKDSSYIEYNRFFNSLAHWDS---------------------------RRSGDIIIYYKLPFDYSDIPAADI-----------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :: : . : .*: . .:.:* : .**:**:** :* .* ** **** :*.* :*::: *::: * *: : *:: *:*:: .: : : ::. : * :* : :**: *: * ** :** :: * .. : . :. . **:: : * * : . . * : : . .:. . ** :. : . .***:*. . *** ***:: .:* ::* . .* . : : :::: . * * : ******: *: *: : . .* : . . : . .: * . .*: *.:::* :: .: ::******* *::* :::* * **:* :: : :: : *:::: *. : : : ** . . . * . * :* : ", "identical_positions": 92, "similar_positions": 147, "identity": "12.67%" }, { "cls_id": "homologset.agr.MGI:1891826", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A0G2K6I6-1", "uniprot_id": "A0A0G2K6I6_RAT", "id": "A0A0G2K6I6-1", "name": "Tubulin delta chain", "aln": "MSIVTVQLGQCGNQIGFEVFDTLFRDSHCSQGLCSKRENEAYQASCKERFFREEENGVPVARAVLIDMEPKVINQTLSKAAQSGRWKYGQHTSFCQKQGSGNNWAYGYSVHGPKHEESIMNLIQTEVEKCDSLSGFFIIMSMAGGTGSGLGAFITQKLQDQYSSSLKMNQIIWPYGTGEVIVQNYNSILTLSHLYRSSDALLIHENDVVHKICAKRMNIKQISFRDLNRVLAHQLGSVFQPTHSEDSSFHYCRNPLGDLMEHLVPHPEFKMLGVRNIPQMSAESLAYSTFTWAGLLKHLRQMLISRAKMEEGIDWQVRPPLSGLPPIGKASAHKEPHFNTSLANLVILRGREVHSADVGGFRDAALYTSWLEPADAFSVWKTPRPFDKYEKSAALVSNSQLLVKPLDMVVGKAWNMFSSKAYIHQYTKFGMEEEDFLDSFTLLEQVVASYGSLP-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9R1K7-1", "uniprot_id": "TBD_MOUSE", "id": "Q9R1K7-1", "name": "Tubulin delta chain", "aln": "MSIVTVQLGQCGNQIGFEVFDALFRDSHCSQGLCSKRDNEAYQASCRERFFREEENGVPVARAVLVDMEPKVINQTLSKAAQSGRWNYGQHTSFCQKQGSGNNWAYGYSVHGPKHEESIMNLIQTEVEKCDSLSGFFIIMSMAGGTGSGLGAFVTQKLQDQYSSSLKMNQIIWPYGTGEVIVQNYNSILTLSHLYRSSDALLIHENDAVHKICAKRMNIKQISFRDLNQVLAHQLGSVFQPTYSEDSSFHYRRNPLGDLMEHLVPHPEFKMLGVRNIPQMSAASLAYSAFTWAGLLKHLRQMLISSAKMEEGINWQVRPPLTGLPPIGKASAHKEHHFNTSLANLVVLRGREVHSADVEGFKDPALYTSWLEPVDAFSVWKTQRAFDKYEKSAALVSNSQLLVKPLDMIVGKAWNMFSSKAFIHQYTKFGMEEEDFLDSFALLEQVVASYGSLGP", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9UJT1-1", "uniprot_id": "TBD_HUMAN", "id": "Q9UJT1-1", "name": "Tubulin delta chain", "aln": "MSIVTVQLGQCGNQIGFEVFDALLSDSHSSQGLCSMRENEAYQASCKERFFSEEENGVPIARAVLVDMEPKVINQMLSKAAQSGQWKYGQHACFCQKQGSGNNWAYGYSVHGPRHEESIMNIIRKEVEKCDSFSGFFIIMSMAGGTGSGLGAFVTQNLEDQYSNSLKMNQIIWPYGTGEVIVQNYNSILTLSHLYRSSDALLLHENDAIHKICAKLMNIKQISFSDINQVLAHQLGSVFQPTYSAESSFHYRRNPLGDLMEHLVPHPEFKMLSVRNIPHMSENSLAYTTFTWAGLLKHLRQMLISNAKMEEGIDRHVWPPLSGLPPLSKMSLNKDLHFNTSIANLVILRGKDVQSADVEGFKDPALYTSWLKPVNAFNVWKTQRAFSKYEKSAVLVSNSQFLVKPLDMIVGKAWNMFASKAYIHQYTKFGIEEEDFLDSFTSLEQVVASYCNL--", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*********************:*: ***.****** *:********:**** *******:*****:********* ********:*:****:.********************:*******:*:.*******:********************:**:*:****.**************************************:****.:****** ******** *:*:*************:* :***** ********************.*****:** ****::**************** *******: :* ***:****:.* * :*: *****:****:***::*:**** **:*.*******:*.:**.**** *.*.******.******:*******:********:***:********:*********: ******** .* ", "identical_positions": 374, "similar_positions": 59, "identity": "82.2%" }, { "cls_id": "homologset.agr.MGI:1891827", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9JL55-1", "uniprot_id": "GDE1_RAT", "id": "Q9JL55-1", "name": "Glycerophosphodiester phosphodiesterase 1", "aln": "----MWLWEDQGGLLGPFSFVLVLLLVVTRSPFNACVLTG--------SLYLLLRFFSFEPVPS-RRALQVLKPRDRVS---AIAHRGGSHDAPENTLAAIRQAAKNGATGVELDIEFTSDGVPVLMHDNTVDRTTDGSGRLCDLTFEQVRKLNPAANHRLRNEFPDERIPTLREA--VTECLCHNLTIFFDVKGHADMASAALKNIYMEFPQLYNNSMVCSFLPEVIYKMRQTDQKVITALTHRPWSLSHTGDGKPRYSVFWKQSVFVVLDILLDWSMHNVLWYLCGISAFLMQKDFVSPDYLKKWSAKGIQVVSWTVNTFDEKNYYESHLGSSYITDSMLEDCAPHF--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9JL56-1", "uniprot_id": "GDE1_MOUSE", "id": "Q9JL56-1", "name": "Glycerophosphodiester phosphodiesterase 1", "aln": "----MWLWEDQGGLLGPFSFVLVLLLVVTRSPFNACVLTG--------SLYILLRFFSFEPVPS-RRALQVLKPRDRVS---AIAHRGGSHDAPENTLAAIRQAAKNGATGVELDIEFTSDGVPVLMHDNTVDRTTDGSGRLCDLTFEQVRKLNPAANHRLRNEFPDERIPTLKEA--VTECLRHNLTIFFDVKGHADMASAALKNIYTEFPQLYNNSMVCSFLPEVIYKMRQTDQKVITALTHRPWSLSHTGDGKPRYSVFWKQSVFVVLDILLDWSMHNVLWYLCGISAFLMQKDFVSPDYLKKWSAKGIQVVSWTVNTFDEKNYYESHLGSSYITDSMLEDCAPHF--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9NZC3-1", "uniprot_id": "GDE1_HUMAN", "id": "Q9NZC3-1", "name": "Glycerophosphodiester phosphodiesterase 1", "aln": "----MWLWEDQGGLLGPFSFLLLVLLLVTRSPVNACLLTG--------SLFVLLRVFSFEPVPS-CRALQVLKPRDRIS---AIAHRGGSHDAPENTLAAIRQAAKNGATGVELDIEFTSDGIPVLMHDNTVDRTTDGTGRLCDLTFEQIRKLNPAANHRLRNDFPDEKIPTLREA--VAECLNHNLTIFFDVKGHAHKATEALKKMYMEFPQLYNNSVVCSFLPEVIYKMRQTDRDVITALTHRPWSLSHTGDGKPRYDTFWKHFIFVMMDILLDWSMHNILWYLCGISAFLMQKDFVSPAYLKKWSAKGIQVVGWTVNTFDEKSYYESHLGSSYITDSMVEDCEPHF--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VEU9-1", "uniprot_id": "Q9VEU9_DROME", "id": "Q9VEU9-1", "name": "Glycerophosphodiester phosphodiesterase 1", "aln": "MSYWRLLWLALKMIYQLLCCSVSLIFFCFNVFWLFCNLAIPWCTLTLLVVCIASKFVKLQRSPNEKRLLSLLSSPEEWPSYWPIANRAAGFDAPENSKAAIKKCLARGYRNVLLDAGLTSCGEIVVANPTKIN---------VAQPLVELQKLNITEQHPMGSQYEAETVAPLRQLSDFLEAEAAETTVFLRLHDNSARMINELQKFMTADESFTQRTIVISRSPLAIYQLRKLKPEIICGLWHETYLSLAILKSS------------TLITSIYGAIFRNIIAPVIGISVVFLSKDEINFHIADLWRNVGVRPIVYMVNSPNEKRYFQKTMKIQYLTDSLRSEPHLLMKA", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ** : :. : :::. . * *: : : :...:: *. * *.:*.. :. . .**:*....*****: ***::. .* .* ** :** * *: : ..:: .: :::*** : :* : .:: * :..*:: . *. : *:*: ::.:: *::: .: :.::* * * .**::*: . .:* .* *..: ... .:: : . ::*:: : ***..::.** :. . * *:: : : **: :** *::. : .*:***: .: : ", "identical_positions": 63, "similar_positions": 128, "identity": "17.95%" }, { "cls_id": "homologset.agr.MGI:1891828", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O88597-1", "uniprot_id": "BECN1_MOUSE", "id": "O88597-1", "name": "Beclin-1", "aln": "----------------------------MEGSKASS-STMQVS----FVCQRCSQPLKLDTSFKILDRVTIQELTAP--LLTTAQAKPGETQEEEANSGEEPFIET-RQDGVSRRFIPPARMMSTESANSFTLIGEASDGGTMEN-----------LSRRLKVTGDLFDIMSGQTDVDHPLCEECTDTLLDQLDTQLNVTENECQNYKRCLEILEQMNED-DSEQLQR-------ELKELALEEERLIQELEDVEKNRKVVAENLEKVQAEAERLDQEEAQYQREYSEFKRQQLELDDELKSVENQVRYAQIQLDKLKKTNVFNATFHIWHSGQFGTINNFRLGRLPSVPVEWNEINAAWGQTVLLLHALANKMGLKFQRYRLVPYGNHSYLESLTDKSKELPLYCS------------------GGLRFFWDNKFDHAMVAFLDCVQQFKEEVEKGETRFCLP----YRMDVEKGKIEDTGGSGGSYSIKTQFNSEEQ---------------WTKALKFMLTNLKWGLAWVSSQFYNK-----------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q91XJ1-1", "uniprot_id": "BECN1_RAT", "id": "Q91XJ1-1", "name": "Beclin-1", "aln": "----------------------------MEGSKASS-STMQVS----FVCQRCSQPLKLDTSFKILDRVTIQELTAP--LLTTAQAKPGESQEEEANSGEEPFIET-RQDGVSRRFIPPARMMSTESANSFTLIGEASDGGTMEN-----------LSRRLKVTGDLFDIMSGQTDVDHPLCEECTDTLLDQLDTQLNVTENECQNYKRCLEMLEQMNEG-DSEQLQR-------ELKELALEEERLIQELEDVEKNRKVVAENLEKVQAEAERLDQEEAQYQREYSEFKRQQLELDDELKSVENQMRYAQMQLDKLKKTNVFNATFHIWHSGQFGTINNFRLGRLPSAPVEWNEINAAWGQTVLLLHALANKMGLKFQRYRLVPYGNHSYLESLTDKSKELPLYCS------------------GGLRFFWDNKFDHAMVAFLDCVQQFKEEVEKGETRFCLP----YRMDVEKGKIEDTGGSGGSYSIKTQFNSEEQ---------------WTKALKFMLTNLKWGLAWVSSQFYNK-----------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q14457-1", "uniprot_id": "BECN1_HUMAN", "id": "Q14457-1", "name": "Beclin-1", "aln": "----------------------------MEGSKTSNNSTMQVS----FVCQRCSQPLKLDTSFKILDRVTIQELTAP--LLTTAQAKPGETQEEETNSGEEPFIETPRQDGVSRRFIPPARMMSTESANSFTLIGEASDGGTMEN-----------LSRRLKVTGDLFDIMSGQTDVDHPLCEECTDTLLDQLDTQLNVTENECQNYKRCLEILEQMNED-DSEQLQM-------ELKELALEEERLIQELEDVEKNRKIVAENLEKVQAEAERLDQEEAQYQREYSEFKRQQLELDDELKSVENQMRYAQTQLDKLKKTNVFNATFHIWHSGQFGTINNFRLGRLPSVPVEWNEINAAWGQTVLLLHALANKMGLKFQRYRLVPYGNHSYLESLTDKSKELPLYCS------------------GGLRFFWDNKFDHAMVAFLDCVQQFKEEVEKGETRFCLP----YRMDVEKGKIEDTGGSGGSYSIKTQFNSEEQ---------------WTKALKFMLTNLKWGLAWVSSQFYNK-----------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F1RCP1-1", "uniprot_id": "BECN1_DANRE", "id": "F1RCP1-1", "name": "Beclin-1", "aln": "----------------------------METLRFSS-NTMQVS----FVCQRCNQPLKLDTSFNVLDRMTIHELTAP--LVMVTANKQQDSGESSSFP-EETFLEN-KQDGVARKFIPPARMMSAESTNSFTLIGEASDGGTMEN-----------LSRRLKVTSNLFDIMSGQTDIDHPLCEECTDTLLDHLDTQLNITENECQNYKSCLELLSQLPEE-EEASLLN-------ALQQLKQEEESLIQELESIETKREAVAKELDEGRNHSQLMDTEELRYQKEYCEFKRQQLELDDDLKSVDNQMRYCQIQLDKLKKTNVFNATFHIWHSGQFGTINNFRLGRLPSVPVEWNEINAAWGQTVLLLHALASKMGLCFQRYQLVPYGNHSYLESLSDKSKELPLYCS------------------GGLRFFWDNKFDHAMVAFLDCVQQFKEEVEKDDTGFCLP----YRMDVDKGKIEDTGGSGGSYSIKTQFNSEEQ---------------WTKALKFMLTNLKWGLAWVSSQFYNR-----------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VCE1-1", "uniprot_id": "BECN1_DROME", "id": "Q9VCE1-1", "name": "Beclin-1-like protein", "aln": "---------------------------------MSEAEKQAVS----FACQRCLQPIVLDEQLEKISVHAMAELSLP--IYGDNGN-TLDPQDASSFD----------------HFVPPYRLTDSINGTGFMLV---SDGRDNKK-----------MSAAFKLKAELFDCLSSNSEIDHPLCEECADSMLEIMDRELRIAEDEWDVYKAYLDELEQQRVAPNVEALDK-------ELDELKRSEQQLLSELKELKKEEQSLNDAIAEEEQEREELHEQEESYWREYTKHRRELMLTEDDKRSLECQIAYSKQQLDKLRDTNIFNITFHIWHAGHFGTINNFRLGRLPSVSVDWSEINAAWGQTVLLLSALARKIGLTFERYRVVPFGNHSYVEVLGE-NRELPLYGS------------------GGFKFFWDTKFDAAMVAFLDCLTQFQKEVEKRDTEFLLP----YKME--KGKIIDP-STGNSYSIKIQFNSEEQ---------------WTKALKFMLTNLKWGLAWVSSQFVSP-----------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q02948-1", "uniprot_id": "BECN1_YEAST", "id": "Q02948-1", "name": "Vacuolar protein sorting-associated protein 30", "aln": "MKCQTCHLPLQLDPSLEGLSLTQRNLLLSNNSIITATNENVISNKGIEAADNCGPQIPKERLRRLGEIQNIKDLNLKDDKLITDSFVFLNHDDDDNANITSNSREDQRYGNANGNDNKKANSDTSDGTSTFRDHDEEEQEATDEDENQQIQLNSKTLSTQVNAMTNVFNILSSQTNIDFPICQDCCNILINRLKSEYDDAIKERDTYAQFLSKLESQNKEISESNKEKQYSHNLSEKENLKKEEERLLDQLLRLEMTDDDLDGELVRLQEKKVQLENEKLQKLSDQNLMDLNNIQFNKNLQSLKLQYELSLNQLDKLRKINIFNATFKISHSGPFATINGLRLGSIPESVVPWKEINAALGQLILLLATINKNLKINLVDYELQPMGSFSKIKKRMVNSVEYNNSTTNAPGDWLILPVYYDENFNLGRIFRKETKFDKSLETTLEIISEITRQLSTIASSYSSQTLTTSQDESSMNNANDVENSTSILELPYIMNKDKINGLSVKLHGSSPNLEWTTAMKFLLTNVKWLLAFSSNLLSKSITLSPTVNYNDKTISGN", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . :* ..:.* : : . . : :*. : : . . . : . . * .: :. :* .: ::*: :*.::::*.*:*::* : ::: :. : : .* : * *. *.. . .:* .*: *:.:* :: . : : . . . :. :: : : : :.: :*:. * . *****:. *:** **:* *:* *.***.:*** :*. * *.***** ** :*** :: :: : : *.: * *..* :: . * : * * :.*** :: : *: : :: .::.. : : : : .: * .: . .: :*.:: **.*:**:***:** **: *. : . ", "identical_positions": 80, "similar_positions": 148, "identity": "14.36%" }, { "cls_id": "homologset.agr.MGI:1891829", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P62878-1", "uniprot_id": "RBX1_MOUSE", "id": "P62878-1", "name": "E3 ubiquitin-protein ligase RBX1", "aln": "MAAAMD-VDTPS--------GTNSG----AGKKRFEVK--KWNAVALWAWDIVVDNCAICRNHIMDLCIECQANQASATSEECTVAWGVCNHAFHFHCISRWLKTRQVCPLDNREWEFQKYGH", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P62877-1", "uniprot_id": "RBX1_HUMAN", "id": "P62877-1", "name": "E3 ubiquitin-protein ligase RBX1", "aln": "MAAAMD-VDTPS--------GTNSG----AGKKRFEVK--KWNAVALWAWDIVVDNCAICRNHIMDLCIECQANQASATSEECTVAWGVCNHAFHFHCISRWLKTRQVCPLDNREWEFQKYGH", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A0G2JUC8-1", "uniprot_id": "A0A0G2JUC8_RAT", "id": "A0A0G2JUC8-1", "name": "E3 ubiquitin-protein ligase RBX1", "aln": "MARELV-TEAAA--------EILTSLLCYPENALFPLFSLQWNAVALWAWDIVVDNCAICRNHIMDLCIECQANQASATSEECTVAWGVCNHAFHFHCISRWLKTRQVCPLDNREWEFQKYGH", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9W5E1-1", "uniprot_id": "RBX1A_DROME", "id": "Q9W5E1-1", "name": "RING-box protein 1A", "aln": "MEVDEDGYEVPS--------SSSKG-----DKKRFEVK--KWNAVALWAWDIVVDNCAICRNHIMDLCIECQANQASATSEECTVAWGVCNHAFHFHCISRWLKTRQVCPLDNREWDFQKYGH", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q08273-1", "uniprot_id": "RBX1_YEAST", "id": "Q08273-1", "name": "RING-box protein HRT1", "aln": "MSNEVDRMDVDEDESQNIAQSSNQSAPVETKKKRFEIK--KWTAVAFWSWDIAVDNCAICRNHIMEPCIECQPKAMTDTDNECVAAWGVCNHAFHLHCINKWIKTRDACPLDNQPWQLARCGR", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* :. . : * : :*.***:*:***.************: *****.: : *.:**..**********:***.:*:***:.*****: *:: : *:", "identical_positions": 54, "similar_positions": 29, "identity": "43.9%" }, { "cls_id": "homologset.agr.MGI:1891830", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I5YBE4-1", "uniprot_id": "A0A8I5YBE4_RAT", "id": "A0A8I5YBE4-1", "name": "Plakophilin-3", "aln": "----MQEGNFLLSALQPEAGVCSLALPSDLQLDRRGAEGPEADRLRAARVQEQVRARLLQLGQQS-RHNGSTELDGSAESTRGLPRGQYHTMQSGFSSRSQGMSGDKTSTFRPIAKPAYNPASWSSRSAVDLTCSRRLSSAHNGGSAFG-AVGYGGAQPTPPMPTRPVSFHERGGAASRADYDTLSLRSLRLGPGGLDDRYSVVSEQLEPAAASTYRAYA--YERQASSSSSRAGGLDWPEATEGPPSRTIRAPAMRTLQRFQSSHRS-RGGTGSVSGAGLEPVARAPSVRSLSLSLGDSGHLPDV-RGLDSYT--GHRTLQRLSSGFDDIDLPSAVKYLMASDPNLQVLGAAYIQHRCYSDAAAKKQARSLQAVPRLVKLFNHANQEVQRHATGAMRNLIYDNVDNKLALVEENGIFELLRTLREQDDELRKNVTGILWNLSSSDHLKDRLARDTLEQLTDLVLSPLSGAGGPPLIQQNASEAEIFYNATGFLRNLSSASQATRQKMRECHGLVDALVTYINHALDVGKCEDKSVENAVCVLRNLSYRLYDEMPPSALQRLEGRGRRDMAGAPPGEVVGCFTPQSRRLRELPLTADALTFAEVSKDPKGLEWLWSPQIVGLYNRLLQRCELNRHTTEAAAGALQNITAGDRRWAGVLSRLALEQERILNPLLDRVRTADHNQLRSLTGLIRNLSRNARNKDEMSTKVVSHLIEKLPGSVGEKCPPAEVLVNIIAVLNNLVVASPIAARDLLYFDGLRKLVFIKKKRD-SPDSEKSSRAASSLLANLWQYSKLHRDFRAKGYRKEDFLGP--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9QY23-1", "uniprot_id": "PKP3_MOUSE", "id": "Q9QY23-1", "name": "Plakophilin-3", "aln": "----MQEGNFLLSALQPETGVCSLALPSDLQLDRRGAEGPEADRLRAARVQEQVRARLLQLGQQS-RHNGSAELDGSAESARGMPRGQYHTMQTGFSSRSQGMSGDKTSTFRPIAKPAYSPASWSSRSAVDLTCSRRLSSAHNGGSAFG-AVGYGGTQPTPPMPTRPVSFHERGGAASRADYDTLSLRSLRLGPGGLDDRYSVVSEQLEPAAASTYRAYA--YERQASSGSSRAGGLDWPEATEGPPSRTIRAPAMRTLQRFQSSHRS-RGGTGSVSGAGLEPVARAPSVRSLSLSLADSGHLPDV-RGLDSYT--GHRTLQRLSSGFDDIDLPSAVKYLMASDPNLQVLGAAYIQHRCYSDAAAKKQARSLQAVPRLVKLFNHANQEVQRHATGAMRNLIYDNVDNKLALVEENGIFELLRTLREQDDELRKNVTGILWNLSSSDHLKDRLARDTLEQLTDLVLSPLSGAGGPPLIQQNASEAEIFYNATGFLRNLSSASQATRQKMRECHGLVDALVTYINHALDVGKCEDKSVENAVCVLRNLSYRLYDEMPPSALQRLEGRGRRDMAGAPPGEMVGCFTPQSRRLRELPLTADALTFAEVSKDPKGLEWLWSPQIVGLYNRLLQRCELNRHTTEAAAGALQNITAGDRRWAGVLSRLALEQERILNPLLDRVRTADHNQLRSLTGLIRNLSRNARNKDEMSTKVVSHLIEKLPGSVGEKCPPAEVLVNIIAVLNNLVVASPIAARDLLYFDGLRKLVFIKKKRD-SPDSEKSSRAASSLLANLWQYSKLHRDFRAKGYRKEDFLGP--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9Y446-1", "uniprot_id": "PKP3_HUMAN", "id": "Q9Y446-1", "name": "Plakophilin-3", "aln": "----MQDGNFLLSALQPEAGVCSLALPSDLQLDRRGAEGPEAERLRAARVQEQVRARLLQLGQQP-RHNGAAEPEPEAETARGTSRGQYHTLQAGFSSRSQGLSGDKTSGFRPIAKPAYSPASWSSRSAVDLSCSRRLSSAHNGGSAFG-AAGYGGAQPTPPMPTRPVSFHERGGVGSRADYDTLSLRSLRLGPGGLDDRYSLVSEQLEPAATSTYRAFA--YERQASSSSSRAGGLDWPEATEVSPSRTIRAPAVRTLQRFQSSHRS-RGVGGAVPGAVLEPVARAPSVRSLSLSLADSGHLPDV-HGFNSYG--SHRTLQRLSSGFDDIDLPSAVKYLMASDPNLQVLGAAYIQHKCYSDAAAKKQARSLQAVPRLVKLFNHANQEVQRHATGAMRNLIYDNADNKLALVEENGIFELLRTLREQDDELRKNVTGILWNLSSSDHLKDRLARDTLEQLTDLVLSPLSGAGGPPLIQQNASEAEIFYNATGFLRNLSSASQATRQKMRECHGLVDALVTSINHALDAGKCEDKSVENAVCVLRNLSYRLYDEMPPSALQRLEGRGRRDLAGAPPGEVVGCFTPQSRRLRELPLAADALTFAEVSKDPKGLEWLWSPQIVGLYNRLLQRCELNRHTTEAAAGALQNITAGDRRWAGVLSRLALEQERILNPLLDRVRTADHHQLRSLTGLIRNLSRNARNKDEMSTKVVSHLIEKLPGSVGEKSPPAEVLVNIIAVLNNLVVASPIAARDLLYFDGLRKLIFIKKKRD-SPDSEKSSRAASSLLANLWQYNKLHRDFRAKGYRKEDFLGP--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F1QWE6-1", "uniprot_id": "F1QWE6_DANRE", "id": "F1QWE6-1", "name": "", "aln": "MSAVAATEGLFFSALQPNTSVTTYAIPTDDHRRR-------DQLSKVRRVQQQVQQRMAEKSTSSSRLNASTEFNGHSPTVA------YQTRSPGFSSKSMIYNGNRTMAVPRLSQYAG---DFSSRSAVETGTRHRISLGVPMPAVVGRPYTYHDDAHLSSSYNQMQTSESRTLSRTEQEVAAMAGLTLQRQPSPVGNWMPNYGQSPSPNTAHRQRTLSGTLAREGFNTGWREAELANQYAFKGPSHRTISRINNRQVQQQQHQRLSGSSMQWQQMSTGGNSLMGAGHYQGTIKRAGSVHSMKSVGRGVDVYDGLADGTADGLG-GIHNLDMTTAVSYLSSTDVSMQMLGAAYVQHQCYHSNEAKTMVRSLKGISALVQLFSSENQEVQRYATGATRNLIYENMDNKTALIEAGGISKLIGALREPDDELRKNITGILWNLSSKDSLKERLARESLAELTERVLVPLSGGGDAGVIQQSASEADIFFNTTGCLRNLSSVNERTRQQMRETRGLVDSLVGYIQNSLQEGKGENKGVENCVCVLRNLSYQLYSEIPSSVQMRLEGPTR--AQDTRHSDAIGCFTPQSKKAKDR--NQDLTTFTEVARVPKGAEWLWHPQIVSLYNQILQSCEANTATREAAAGALQNITAGDSRWASVLSRVALEQERMLPVILDLLRSPTDAELRSLTGLLRNLSRHCKNKADMATKVVNVLVNKLPSDGHQKEPSSEVVVNICGVLNNLVTGSSLAARDITYFDGLPKLVSIKSSHDNSPGKLKAARAASTVLSNMFQYNKLHRDYKQKGFARRDFTDGII", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .:::*****::.* : *:*:* : * : :. ***:**: *: : . .. * *.::* : : :. *:* ..****:* .*::* . ::: * .:******: :*:* . :..* . * . .. .: : ..* :. : ::: :*: *. :.: . .:. .* :: *: : *:. . . * . * * : .. *** * :*: * .: * . .: :.: * :. .. : .* :*.: * .. * : *. *:.::*:.:**.** ::* .:*:*****:**:** . **. .***:.:. **:**. ******:**** *****:* *** **:* .** :*: :*** *******:*********.* **:****::* :**: ** ****.*.. :***.****:**:*:** ******..: ***:*** :****:** *:::*: ** *:*.***.*********:**.*:*.*. **** * .: .: :*******:: :: * **:**:: *** **** ****.***::** ** * * ************** ***.****:******:* :** :*:. . :*******:*****:.:** :*:****. *::***.. :* *.:**:*** .******..*.:****: ***** **: **..:* **.. *::****::*:*::**.*****:: **: :.** . ", "identical_positions": 340, "similar_positions": 238, "identity": "41.87%" }, { "cls_id": "homologset.agr.MGI:1891831", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "G3V9A3-1", "uniprot_id": "G3V9A3_RAT", "id": "G3V9A3-1", "name": "", "aln": "---MERASLIQKAKLAEQAERYEDMAAFMKSAVEKGEELSCEERNLLSVAYKNVVGGQRAAWRVLSSIEQKSNEEGSEEKGPEVKEYREKVETELRGVCDTVLGLLDSHLIKGAGEAESRVFYLKMKGDYYRYLAEVATGDDKKRIIDSARSAYQEAMDISKKEMPPTNPIRLGLALNFSVFHYEIANSPEEAISLAKTTFDEAMADLHTLSEDSYKDSTLIMQLLRDNLTLWTADNAGEEGGEAPEEPQS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O70456-1", "uniprot_id": "1433S_MOUSE", "id": "O70456-1", "name": "14-3-3 protein sigma", "aln": "---MERASLIQKAKLAEQAERYEDMAAFMKSAVEKGEELSCEERNLLSVAYKNVVGGQRAAWRVLSSIEQKSNEEGSEEKGPEVKEYREKVETELRGVCDTVLGLLDSHLIKGAGDAESRVFYLKMKGDYYRYLAEVATGDDKKRIIDSARSAYQEAMDISKKEMPPTNPIRLGLALNFSVFHYEIANSPEEAISLAKTTFDEAMADLHTLSEDSYKDSTLIMQLLRDNLTLWTADSAGEEGGEAPEEPQS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P31947-1", "uniprot_id": "1433S_HUMAN", "id": "P31947-1", "name": "14-3-3 protein sigma", "aln": "---MERASLIQKAKLAEQAERYEDMAAFMKGAVEKGEELSCEERNLLSVAYKNVVGGQRAAWRVLSSIEQKSNEEGSEEKGPEVREYREKVETELQGVCDTVLGLLDSHLIKEAGDAESRVFYLKMKGDYYRYLAEVATGDDKKRIIDSARSAYQEAMDISKKEMPPTNPIRLGLALNFSVFHYEIANSPEEAISLAKTTFDEAMADLHTLSEDSYKDSTLIMQLLRDNLTLWTADNAGEEGGEAPQEPQS", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P29310-1", "uniprot_id": "1433Z_DROME", "id": "P29310-1", "name": "14-3-3 protein zeta", "aln": "MSTVDKEELVQKAKLAEQSERYDDMAQAMKSVTETGVELSNEERNLLSVAYKNVVGARRSSWRVISSIEQKT--EASARKQQLAREYRERVEKELREICYEVLGLLDKYLIPKASNPESKVFYLKMKGDYYRYLAEVATGDARNTVVDDSQTAYQDAFDISKGKMQPTHPIRLGLALNFSVFYYEILNSPDKACQLAKQAFDDAIAELDTLNEDSYKDSTLIMQLLRDNLTLWTSDTQGDE-AEPQEGGDN", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ::: .*:********:***:*** **...*.* *** ***************.:*::***:******: *.* .* .:****:**.**: :* ******.:** *.:.**:********************* :: ::*.:::***:*:**** :* **:*************:*** ***::* .*** :**:*:*:*.**.**********************:*. *:* .*. : :.", "identical_positions": 159, "similar_positions": 61, "identity": "63.35%" }, { "cls_id": "homologset.agr.MGI:1891832", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q5NBY9-1", "uniprot_id": "PATZ1_MOUSE", "id": "Q5NBY9-1", "name": "POZ (BTB) and AT hook-containing zinc finger 1", "aln": "MERVNDASCGPSGCYTYQVSRHSTEMLHNLNQQRKNGGRFCDVLLRVGDESFPAHRAVLAACSEYFESVFSAQLGDGGAADGGPADVGGAAAAPGGGAGGSRELEMHTISSKVFGDILDFAYTSRIVVRLESFPELMTAAKFLLMRSVIEICQEVIKQSNVQILVPPAR-ADIMLFRPPGTSDLGFPLDMTNGAAMAANSNGIAGSMQPEEEAARATGAAIAGQASLPVLPGVDRLPMVAGPLSPQLLTSPFPNVASSAPPLTSKRGRGRPRKANLLDSMFG--SPGGLREAGILPCGLCGKVFTDANRLRQHEAQHGVTS------LQLGYIDLP--PPRLGENGLPISEDPDGPRKRSRTRKQVACEICGKIFRDVYHLNRHKLSHSGEKPYSCPVCGLRFKRKDRMSYHVRSHDGSVGKPYICQSCGKGFSRPDHLNGHIKQVHTSERPHKCQTCNASFATRDRLRSHLACHEDKVPCQVCGKYLRAAYMADHLKKHSEGPSNFCSICNRGFSSASYLKVHVKTHHG---VPLPQVSRHQEPILN-----GGAAFHCAR------------------------------------------------------------------------TYGNKEGQKCSHQDLIESSDSYGDLSDASDLKTPEKQS----------ANGSFSCDVAVP---KNKMESDGEKKYPCPECGSFFRSKSYLNKHIQKVHVRALGGPLGDLGPALGSPFSPQQNMSLLESFGFQIVQSAFASSLVDPEVDQQPMGPEGK", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A0G2K420-1", "uniprot_id": "A0A0G2K420_RAT", "id": "A0A0G2K420-1", "name": "BTB/POZ domain zinc finger transcription factor", "aln": "MERVNDASCGPSGCYTYQVSRHSTEMLHNLNQQRKNGGRFCDVLLRVGDESFPAHRAVLAACSEYFESVFSAQLGDGGAADGGPADVGGAAAAPGGGAGGSRELEMHTISSKVFGDILDFAYTSRIVVRLESFPELMTAAKFLLMRSVIEICQEVIKQSNVQILVPPAR-ADIMLFRPPGTSDLGFPLDMTNGAAMAANSNGIAGSMQPEEEAARATGAAIAGQASLPVLPGVDRLPMVAGPLSPQLLTSPFPNVASSAPPLTGKRGRGRPRKANLLDSMFG--SPGGLREAGILPCGLCGKVFTDANRLRQHEAQHGVTS------LQLGYIDLP--PPRLGENGLPISEDPDGPRKRSRTRKQVACEICGKIFRDVYHLNRHKLSHSGEKPYSCPVCGLRFKRKDRMSYHVRSHDGSVGKPYICQSCGKGFSRPDHLNGHIKQVHTSERPHKCQTCNASFATRDRLRSHLACHEDKVPCQVCGKYLRAAYMADHLKKHSEGPSNFCSICNRGFSSASYLKVHVKTHHG---VPLPQVSRHQEPILN-----GGAAFHCAR------------------------------------------------------------------------TYGNK-GQKCSHQDLIESSDSYGDLSDASDLKTPEKQS----------ANGSFSCDMAVP---KNKMESDGEKKYPCPECGSFFRSKSYLNKHIQKVHVRALGGPLGDLGPALGSPFSPQQNMSLLESFGFQIVQSAFASSLVDPEVDQQPIGPEGK", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9HBE1-1", "uniprot_id": "PATZ1_HUMAN", "id": "Q9HBE1-1", "name": "POZ-, AT hook-, and zinc finger-containing protein 1", "aln": "MERVNDASCGPSGCYTYQVSRHSTEMLHNLNQQRKNGGRFCDVLLRVGDESFPAHRAVLAACSEYFESVFSAQLGDGGAADGGPADVGGATAAPGGGAGGSRELEMHTISSKVFGDILDFAYTSRIVVRLESFPELMTAAKFLLMRSVIEICQEVIKQSNVQILVPPAR-ADIMLFRPPGTSDLGFPLDMTNGAALAANSNGIAGSMQPEEEAARAAGAAIAGQASLPVLPGVDRLPMVAGPLSPQLLTSPFPSVASSAPPLTGKRGRGRPRKANLLDSMFG--SPGGLREAGILPCGLCGKVFTDANRLRQHEAQHGVTS------LQLGYIDLP--PPRLGENGLPISEDPDGPRKRSRTRKQVACEICGKIFRDVYHLNRHKLSHSGEKPYSCPVCGLRFKRKDRMSYHVRSHDGSVGKPYICQSCGKGFSRPDHLNGHIKQVHTSERPHKCQTCNASFATRDRLRSHLACHEDKVPCQVCGKYLRAAYMADHLKKHSEGPSNFCSICNRGFSSASYLKVHVKTHHG---VPLPQVSRHQEPILN-----GGAAFHCAR------------------------------------------------------------------------TYGNKEGQKCSHQDPIESSDSYGDLSDASDLKTPEKQS----------ANGSFSCDMAVP---KNKMESDGEKKYPCPECGSFFRSKSYLNKHIQKVHVRALGGPLGDLGPALGSPFSPQQNMSLLESFGFQIVQSAFASSLVDPEVDQQPMGPEGK", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AB32TT90-1", "uniprot_id": "A0AB32TT90_DANRE", "id": "A0AB32TT90-1", "name": "", "aln": "MERTEQPWN---SSYTYQVSKHSAEMLHNLNGQRKDGGRFCDVILRVGEESFPAHKAVLAACSEYFESVFSCQTEDDGQG---------------------KELEMHTISPKVFRDILDFAYTSKIVVRLECFPELMTAAKFLLMRSVIEICQEVIKQSNVQILVPPSRGGEHSLFRAAEQLSYPLPVDMSNGSVSN-------GAVFTDNNDSDSADPSNISQPAAPGAPTADRL-----AVSPLEFSSGHLNIDG------FKRGKPRPKKEPIAQPVTYNNSTGQNEEGALFSCGICGKMFPDEVQLRNHEAQHGTFTGVMSSGIELVVVDGPTMISHPGQQRFQGNGLPTDTRKRERTRRHVACDLCGKVFRDVYHLNRHKLSHSGEKPYACPVCGLRFKRKDRMSYHVRSHDGSVGKPYVCQSCGKGFSRPDHLNGHIKQVHTTERPHKCQICNASFATRDRLRSHLACHEDKIPCQVCGKYLRAAYMTDHLKKHSEGPHNYCGICNKGFSTASYLKVHVKTHHSSSMLPSSAAHQFPEPRTNRPQTHNGAPYHSGRQCAVEDLCTSRRLLVTFPETEGSFRGLSGPVLPQPVPPGLQPELLMGKPGPTPYFWECRSSGAPGFPLHGPLPDGQENAGKCPHQDSDGSDAVFGDLSNGMDLKAEHKVEGEEMEVTSFIFNGQPDDAVTSPEGSKNIPTTDQEKKFACGECGQAFRTKSYLNKHHHRVHKKRAAAAS-SLG-DLASPFSPQQNMSLLESFGFQIVQSAFASSLVDSEIGSSGMGLGEK", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "***.::. ..******:**:******* ***:*******:****:******:***************.* *.* . :********.*** *********:******.***********************************:* .: ***.. . :*:**:**:. *:: .::: : ::..: .*.: * * .*** .:** ::* . .: . ***: **:* : :.: *.* .*..::.**:***:*.* :**:******. : ::* :* * .: *:: : . * ..***.***::***::***:********************:*****************************:***********************:******* *********************:**************:********** *:*.***:***:************. :* . . :. ** * .**.:*..* . *:: . **.*** *. :****:. ***: .* . **. . :: * ** :* ***:.* ***. **:******* ::** : ... .** *.******************************.*:... :* *", "identical_positions": 404, "similar_positions": 146, "identity": "51.07%" }, { "cls_id": "homologset.agr.MGI:1891833", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9WUA3-1", "uniprot_id": "PFKAP_MOUSE", "id": "Q9WUA3-1", "name": "ATP-dependent 6-phosphofructokinase, platelet type", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------MS--------DLDSS-SSSAYPKYLEHLS-----------------------GDGKAIGVLTSGGDAQGMNAAVRAVVRMGIYTGAKVYFIYEGYQGLVDGGSNIVEAKWDCVSSILQVGGTIIGSARCKAFRSREGRLKAACNLARLGITNLCVIGGDGSLTGANLFRKEWSGLLEELARNGDIDNDTVQKYSYLNVVGMVGSIDNDFCGTDMTIGTDSALHRIIEVVDAIMTTAQSHQRTFVLEVMGRHCGYLALVSALTCGADWVFLPE-SPPEEDWEENMCLKLSENRARKKRLNIIIVSEGAIDMQNKPITSEKIKELVVKNLGFDTRVTILGHVQRGGTPSAFDRILASRMGVEAVIALLEATPETPACVVSLRGNQAVRLPLMECVQMTQDVQKAMDERRFKEAVKLRGRRFEGNLNTYKRLAIKLPDEKIVKSN------CNVAVINVGAPAAGMNAAVRSAVRVGIADGHKMFAIYDGFEGFAN-GQIKEIGWADVGGWTGQGGSILGTKRTLPGKYLEKIAEQMHSHSINALLIIGGFEAYLGLLELAAAREKHEAFCVPMVMVPATVSNNVPGS---------------------------------------------------DFSIGADTALNTITDTCDRIKQSASGTKRRVFIIETMGGYCGYLANMGALAAGADAAYIFEEPFDIGDLQSNVVHLTEKMKTSIQRG----LVLRNESCSVNYTTDFIYQLYSEEGKGVFDCRKNVLGHMQQGGAPSPFDRNFGTKISAKAMEWISAKLKG---------------SQGTGK---KFV-SDDSICVLGICKRDLLFQPVAELKK-VTDFEHRIPKEQWWLKLRPIMKILAKYEASYDMSDSGKLESLQHHEEL--------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P47860-1", "uniprot_id": "PFKAP_RAT", "id": "P47860-1", "name": "ATP-dependent 6-phosphofructokinase, platelet type", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------MS--------DQDSSTSSTSFPKYLEHLS-----------------------GDGKAIGVLTSGGDAQGMNAAVRAVVRMGIYTGAKVYFIYEGYQGMVDGGSNIVEAKWECVSSILQVGGTIIGSARCQAFRSREGRLKAACNLVRLGITNLCVIGGDGSLTGANLFRKEWSGLLEELAKNGEIDSDTVKKHAYLNVVGMVGSIDNDFCGTDMTIGTDSALHRIIEVVDAIMTTAQSHQRTFVLEVMGRHCGYLALVSALACGADWVFLPE-SPPEEGWEEEMCLKLSENRARKKRLNIIIVSEGAIDTQNKPITSEKIKELVVTNLGFDTRVTILGHVQRGGTPSAFDRILASRMGVEAVLALLEATPETPACVVSLRGNQAVRLPLMECVQMTQDVQKAMDERRFDEAVKLRGRSFEGNLNTYKRLAIKEPDDKIPKSN------CNVAIINVGAPAAGMNAAVRSAVRVGIAEGHKMFAIYDGFDGLAN-GQIKEIGWGDVGGWTGQGGSILGTKRTLPGKYLEKIAEQMHSKNINALLIIGGFEAYLGLLELAAARNKHEAFCVPMVMVPATVSNNVPGS---------------------------------------------------DFSIGADTALNTITDTCDRIKQSASGTKRRVFIIETMGGYCGYLANMGGLAAGADAAYIFEEQFDIRDLQSNVMHLTEKMKTSIQRG----LVLRNENCSVNYTTDFIYQLYSEEGKGVFDCRKNVLGHMQQGGAPSPFDRNFGTKISAKAMEWISAKLKG---------------SHGTGK---KFV-SDDSICVLGIQKRDLLFKPVAELRK-ATDFEHRIPKQQWWLKLRPIMKILAKYEASYDMSDVGKLEPVHNHGELSAI-----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q01813-1", "uniprot_id": "PFKAP_HUMAN", "id": "Q01813-1", "name": "ATP-dependent 6-phosphofructokinase, platelet type", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------MD--------ADDSRAPKGSLRKFLEHLS-----------------------GAGKAIGVLTSGGDAQGMNAAVRAVVRMGIYVGAKVYFIYEGYQGMVDGGSNIAEADWESVSSILQVGGTIIGSARCQAFRTREGRLKAACNLLQRGITNLCVIGGDGSLTGANLFRKEWSGLLEELARNGQIDKEAVQKYAYLNVVGMVGSIDNDFCGTDMTIGTDSALHRIIEVVDAIMTTAQSHQRTFVLEVMGRHCGYLALVSALACGADWVFLPE-SPPEEGWEEQMCVKLSENRARKKRLNIIIVAEGAIDTQNKPITSEKIKELVVTQLGYDTRVTILGHVQRGGTPSAFDRILASRMGVEAVIALLEATPDTPACVVSLNGNHAVRLPLMECVQMTQDVQKAMDERRFQDAVRLRGRSFAGNLNTYKRLAIKLPDDQIPKTN------CNVAVINVGAPAAGMNAAVRSAVRVGIADGHRMLAIYDGFDGFAK-GQIKEIGWTDVGGWTGQGGSILGTKRVLPGKYLEEIATQMRTHSINALLIIGGFEAYLGLLELSAAREKHEEFCVPMVMVPATVSNNVPGS---------------------------------------------------DFSIGADTALNTITDTCDRIKQSASGTKRRVFIIETMGGYCGYLANMGGLAAGADAAYIFEEPFDIRDLQSNVEHLTEKMKTTIQRG----LVLRNESCSENYTTDFIYQLYSEEGKGVFDCRKNVLGHMQQGGAPSPFDRNFGTKISARAMEWITAKLKE---------------ARGRGK---KFT-TDDSICVLGISKRNVIFQPVAELKK-QTDFEHRIPKEQWWLKLRPLMKILAKYKASYDVSDSGQLEHVQPWSV---------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AB32TIC1-1", "uniprot_id": "A0AB32TIC1_DANRE", "id": "A0AB32TIC1-1", "name": "ATP-dependent 6-phosphofructokinase", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------MA--------QSDNK-------RFFENLT-----------------------GAGKAIAVLTSGGDAQGMNAAVRAVVRMGIYVGAKVYFVHEGYQGMVDGGDNIKEATWENVSSMLQVGGTVIGSARCKDFRTHEGRLKAAHNLIQRGITNLCVIGGDGSLTGANLFREEWSGLLAELVQQGLIDEDAAQKYSALHIVGMVGSIDNDFCGTDMTIGTDSALHRIIEVVDAIMTTAQSHQRTFVLEVMGRHCGYLALVSALACGADWVLIPE-MPPEDGWEEKMCQKLSAKRAGMKRLNIIIVAEGAIDRKNQPITSEHVKNLVVSRLGFDTRVTILGHVQRGGTPSAFDRILASRMGVEAVLALLETTANTPACVVSLCGNQSVRLPLMECVQMTQEVQKAMDGKRFEEAVQLRGRSFENNLKTYKLLAHRKPESELPHSN------FNVAVLNVGAPAAGMNAAVRSAVRVGISEGHKMFAVNDGFEGFYK-GQIKEIKWADVGGWTGQGGSLLGTKRTLPAKHIDKIAEQMRKYNINALLVIGGFEAYLGIMELLEARRTYEELCVPMVMVPATVSNNVPGSDLSIGADTALNAITAALECLLQLNEARAKYEEFCIPLCMLPATISNNVPGTDLSIGADTALNAIVETCDRIKQSASGTKRRVFIIETMGGYCGYLATVGGLAAGADAAYIFEEPFDIRDLQANVEHLTEKMKTSIQRG----LVLRNENSNENYTTDFIYQLYTEEGKGVFDCRKNVLGHMQQGGAPSPFDRNFGTKISAKAMQWITKKLNE---------------SYRRGR---VFANTEDSACLLGMRRRAMVFQPVVQLKD-ETDFVHRIPKEQWWLKLRPLMKILAKYKTSYDVSDSGQLEHVVVNRPKASETSVTI", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0AB32THG1-1", "uniprot_id": "A0AB32THG1_DANRE", "id": "A0AB32THG1-1", "name": "ATP-dependent 6-phosphofructokinase", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------MPDTK-------KYIENLS-----------------------GAGKCIGVLTSGGDAQGMNAAVRAVVRMGIYVGAKVYFIHEGYQGMVDGGDNIKEASWESVSSMLQVGGTVIGSARCKDFRTHEGRLHAALNLVQRGITNLCVIGGDGSLTGANLFREEWSGLLDELVQSGQISEDAAQTHSALHIVGMVGSIDNDFCGTDMTIGTDSALHRIIEVVDAIMTTAQSHQRTFVLEVMGRHCGYLALVSALACGADWVLIPE-RPPKDGWEEQMCQKLSENRADKKRLNIIIVAEGAIDQNNKPITTDHIKDLVVSRLGFDTRVTILGHVQRGGTPSAFDRILASRMGVEAVLALLEASPGTPACVVSLCGNQAVRVPLMECVQMTQEVQKAMDEKRFEEAVKLRGRSFENNLNTYKLLSHRKIDTELPHSS------FNVAVLNVGAPAAGMNAAVRSAVRVGITEGHTMFAVSDGFEGFYK-GQIKEIKWGDVGGWTGQGGSLLGTKRTLPAKHVDKIAEQMRIHNINALLVIGGFEAYLGLMELQAARSKHAELCVPMVMVPATVSNNIPGSDLSIGADTAINAITDAFESLLQLVDARSRYEEFCVPLCMLPATISNNVSGTDLSIGADTSLNAIVETCDRIKQSASGTKRRVFIIETMGGYCGYLATVGGLAAGADAAYIYEEPFDIRDLQSNVEHLTEKMKTSIQRG----LVLRNENSNENYTTDFIYQLYSEEGKGVFDCRKNVLGHMQQGGAPSPFDRNFGTKIAAKAMQWISKKLKE---------------FYRDGR---VFANTEDSACLLGMRRRALLFQPVVQLKD-ETDFVHRIPKEQWWLRLRPLMKILAKYKTSYDVSDSGQLEHIVRLRAKDSSAI---", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P52034-1", "uniprot_id": "PFKA_DROME", "id": "P52034-1", "name": "ATP-dependent 6-phosphofructokinase", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------MN--------SEINQ-------RFLARGS-----------------------QKDKGLAVFTSGGDSQGMNAAVRACVRMAIYLGCKVYFIREGYQGMVDGGDCIQEANWASVSSIIHRGGTIIGSARCQDFRERQGRLKAANNLIQRGITNLVVIGGDGSLTGANLFRQEWSSLLDELVKNKTITTEQQEKFNVLHIVGLVGSIDNDFCGTDMTIGTDTALHRIIEAIDAISSTAYSHQRTFIMEVMGRHCGYLALVGGLACEADFIFIPE-MPPKVDWPDRLCSQLAQERSAGQRLNIVIVAEGAMDREGHPITAEDVKKVIDERLKHDARITVLGHVQRGGNPSAFDRILACRMGAEATLALMEATKDSVPVVISLDGNQAVRVPLMECVERTQAVAKAMAEKRWADAVKLRGRSFERNLETYKMLTRLKPPKENFDADGKGIEGYRLAVMHIGAPACGMNAAVRSFVRNAIYRGDVVYGINDGVEGLIA-GNVRELGWSDVSGWVGQGGAYLGTKRTLPEGKFKEIAARLKEFKIQGLLIIGGFESYHAAGQIADQRDNYPQFCIPIVVIPSTISNNVPGT---------------------------------------------------EFSLGCDTGLNEITEICDRIRQSAQGTKRRVFVIETMGGYCGYLATLAGLAGGADAAYIYEEKFSIKDLQQDVYHMASKMAEGVSRG----LILRNEKASENYSTDFIYRLYSEEGKGLFTCRMNILGHMQQGGSPTPFDRNMGTKMAAKCVDWLAAQIKAN--------------IDANGV---VNCKSPDTATLLGIVSRQYRFSPLVDLIA-ETNFDQRIPKKQWWLRLRPLLRILAKHDSAYEEE--GMYITVEEECDTDAVA----", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P16861-1", "uniprot_id": "PFKA1_YEAST", "id": "P16861-1", "name": "ATP-dependent 6-phosphofructokinase subunit alpha", "aln": "MQSQDSCYGVAFRSIITNDEALFKKTIHFYHTLGFATVKDFNKFKHGENSLLSSGTSQDSLREVWLESFKLSEVDASGFRIPQQEATNKAQSQGALLKIRLVMSAPIDETFDTNETATITYFSTDLNKIVEKFPKQAEKLSDTLVFLKDPMGNNITFSGLANATDSAPTSKDAFLEATSEDEIISRASSDASDLLRQTLGSSQKKKKIAVMTSGGDSPGMNAAVRAVVRTGIHFGCDVFAVYEGYEGLLRGGKYLKKMAWEDVRGWLSEGGTLIGTARSMEFRKREGRRQAAGNLISQGIDALVVCGGDGSLTGADLFRHEWPSLVDELVAEGRFTKEEVAPYKNLSIVGLVGSIDNDMSGTDSTIGAYSALERICEMVDYIDATAKSHSRAFVVEVMGRHCGWLALMAGIATGADYIFIPERAVPHGKWQDELKEVCQRHRSKGRRNNTIIVAEGALDDQLNPVTANDVKDALIE-LGLDTKVTILGHVQRGGTAVAHDRWLATLQGVDAVKAVLEFTPETPSPLIGILENKIIRMPLVESVKLTKSVATAIENKDFDKAISLRDTEFIELYENFLSTTVKDDGSELLPVSDR----LNIGIVHVGAPSAALNAATRAATLYCLSHGHKPYAIMNGFSGLIQTGEVKELSWIDVENWHNLGGSEIGTNRSVASEDLGTIAYYFQKNKLDGLIILGGFEGFRSLKQLRDGRTQHPIFNIPMCLIPATVSNNVPGT---------------------------------------------------EYSLGVDTCLNALVNYTDDIKQSASATRRRVFVCEVQGGHSGYIASFTGLITGAVSVYTPEKKIDLASIREDITLLKENFRHDKGENRNGKLLVRNEQASSVYSTQLLADIISEASKGKFGVRTAIPGHVQQGGVPSSKDRVTASRFAVKCIKFIEQWNKKNEASPNTDAKVLRFKFDTHGEKVPTVEHEDDSAAVICVNGSHVSFKPIANLWENETNVELRKGFEVHWAEYNKIGDILS-----------GRLKLRAEVAALAAENK---", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . :: : * :.*:*****: ******** ** .*: *..*: : ***:*:: **. : : * * . : ***:**:**. ** ::** :** ** ** * * *********:***.**..*: **. . : : . * :**:*******:.*** ***: :**.** * :* * :** **.*:*::********:***:..:: **::::** *. * :.: .*: :* * :**:***:* : :*:*::.:*. : * *:::*:********.. *.** ** *.:*. *::* : : . ::.: *: :*:**:*.*: *: * .*: : : .*: **. * :.: : : . .:.::::***:..:***.*: . : *. .: :*..*: *:::*: * ** .* . **: :**:* :. . ** :: .::.*:::****.: . :: * : : :*: ::*:*:***:**: : *:* ** ** :.: * *:***..*:****: *. **:.**:*.. .* ** :.* *: :.: .:: :: : .:: .. *::***... *:*::: : :* .** * * : **:**** *:. ** .::::.:.:.:: : * *: :: : *.*:.:* *:. * : * . . : **: * ", "identical_positions": 250, "similar_positions": 255, "identity": "23.65%" }, { "cls_id": "homologset.agr.MGI:1891834", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O54842-1", "uniprot_id": "NUPR1_RAT", "id": "O54842-1", "name": "Nuclear protein 1", "aln": "MATLPPTAHTSQQPVNIEDEDGILDEYDQYSLAQSYVVGGGRKG--RTKREAAANTNRPSPGGHERKLLTKFQNSERKK--AWR---", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9WTK0-1", "uniprot_id": "NUPR1_MOUSE", "id": "Q9WTK0-1", "name": "Nuclear protein 1", "aln": "MATLPPTANPSQQPLNLEDEDGILDEYDQYSLAHPCVVGGGRKG--RTKREAAANTNRPSPGGHERKLLTKFQNSERKK--AWR---", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O60356-1", "uniprot_id": "NUPR1_HUMAN", "id": "O60356-1", "name": "Nuclear protein 1", "aln": "MATFPPATSAPQQPPGPEDEDSSLDESDLYSLAHSYLGGGGRKG--RTKREAAANTNRPSPGGHERKLVTKLQNSERKKRGARR---", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "E9QCY4-1", "uniprot_id": "E9QCY4_DANRE", "id": "E9QCY4-1", "name": "", "aln": "MSNHVEVKN--IEPTTFENR--YYDEYEYYNLTDRYTECTSRKG--RTKKEASCNTNRPNPAGHERKIVEKLQNAEKNS---KE---", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VKC5-1", "uniprot_id": "Q9VKC5_DROME", "id": "Q9VKC5-1", "name": "Nuclear protein 1", "aln": "------------------MSEAHFDEYEHYNFDHDKHIFSGHSGKQRNKREANEHTNHFDPSGHSRKILTKLMNTNNNNKKAAACKN", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ** : *.: . .:.* *.*:** :**: .*.**.**:: *: *::.:. ", "identical_positions": 17, "similar_positions": 22, "identity": "19.54%" }, { "cls_id": "homologset.agr.MGI:1891835", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q99P96-1", "uniprot_id": "HDAC7_RAT", "id": "Q99P96-1", "name": "Histone deacetylase 7", "aln": "--------------------TPGSQPQPMDLRVGQRPTVEPPPEPALLTLQHPQRLHRHLFLAGLQQQQRSAEPMR---------------------------------------------------------------LSMDPPLPELQGGQQEQELRQLLNKD----KSKRSAVASSVVKQKLAEVILKKQQAALERTVHPSSPSIPYRTLEPLDTEG-----AARSVLSSFLPPVPSLPTEPPEHFPLRKTVSEPNLKLRYKPKKSLERRK-------------------------------------NPLLRKESAPPSLRRRPAETLG---------------------------------------------------DSSPSSSSTPASGCSSPNDSEHGPNPALG-------------------------------------SEADG------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8C2B3-1", "uniprot_id": "HDAC7_MOUSE", "id": "Q8C2B3-1", "name": "Histone deacetylase 7", "aln": "------MHSPGAGCPALQPDTPGSQPQPMDLRVGQRPTVEPPPEPALLTLQHPQRLHRHLFLAGLHQQQRSAEPMR---------------------------------------------------------------LSMDPPMPELQGGQQEQELRQLLNKD----KSKRSAVASSVVKQKLAEVILKKQQAALERTVHPSSPSIPYRTLEPLDTEG-----AARSVLSSFLPPVPSLPTEPPEHFPLRKTVSEPNLKLRYKPKKSLERRK-------------------------------------NPLLRKESAPPSLRRRPAETLG---------------------------------------------------DSSPSSSSTPASGCSSPNDSEHGPNPALG-------------------------------------SEADGDRRTHSTLGPRGPVLGNPHAPLFLHHGLEPEAGGTLPSRLQPILLLDPSVSHAPLWTVPGLGPLPFHFAQPLLTTERLSGSGLHRPLN--------------------------------RTRSEPLPPSATASPLLAPLQPRQDRLKPHVQLIKPAISPPQRPAKPSEKPRLRQIPSAEDLETDGGGVGPMANDG---------------------------------------------------LEHRESGRGPPEGRGSISLQQHQQVPPWEQQHLAGRLSQGSPGDSVLIPLAQVGHRPLSRTQSSPAAPVS----------------------------------------LLSPEPTCQTQVLNSSETPA------TGLVYDSVMLKHQCSCGDNSKHPEHAGRIQSIWSRLQERGLRSQCECLRGRKASLEELQSVHSERHVLLYGTNPLSRLKLDNGKLTGLLAQRTFVMLPCGGVGVDTDTIWNELHSSNAARWAAGSVTDLAFKVASRELKNGFAVVRPPGHHADHSTAMGFCFFNSVAIACRQLQQHG-KASKILIVDWDVHHGNGTQQTFYQDPSVLYISLHRHDDGNFFPGSGAVDEVGTGSGEGFNVNVAWAGGLDPPMGDPEYLAAFRIVVMPIAREFAPDLVLVSAGFDAAEGHPAPLGGYHVSAKCFGYMTQQLMNLAGGAVVLALEGGHDLTAICDASEACVAALLGNKVDPLSEESWKQKPNLSAIRSLEAVVRVHRKYWGCMQRLASCPDSWLPRVPGAD-AEVEAVTALASLSVGILAEDRPSERLVEEEEPMNL-----------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8WUI4-1", "uniprot_id": "HDAC7_HUMAN", "id": "Q8WUI4-1", "name": "Histone deacetylase 7", "aln": "----------------------------MDLRVGQRPPVEPPPEPTLLALQRPQRLHHHLFLAGLQQQ-RSVEPMR---------------------------------------------------------------LSMDTPMPELQVGPQEQELRQLLHKD----KSKRSAVASSVVKQKLAEVILKKQQAALERTVHPNSPGIPYRTLEPLETEG-----ATRSMLSSFLPPVPSLPSDPPEHFPLRKTVSEPNLKLRYKPKKSLERRK-------------------------------------NPLLRKESAPPSLRRRPAETLG---------------------------------------------------DSSPSSSSTPASGCSSPNDSEHGPNPILGSEALLGQRLRLQETSVAPFALPTVSLLPAITLGLPAPARADSDRRTHPTLGPRGPILGSPHTPLFLPHGLEPEAGGTLPSRLQPILLLDPSGSHAPLLTVPGLGPLPFHFAQSLMTTERLSGSGLHWPLS--------------------------------RTRSEPLPPSATAPPPPGPMQPRLEQLKTHVQVIK-------RSAKPSEKPRLRQIPSAEDLETDGGGPGQVVDDG---------------------------------------------------LEHRELGHGQPEARGPAPLQQHPQVLLWEQQRLAGRLPRGSTGDTVLLPLAQGGHRPLSRAQSSPAAPAS----------------------------------------LSAPEPASQARVLSSSETPARTLPFTTGLIYDSVMLKHQCSCGDNSRHPEHAGRIQSIWSRLQERGLRSQCECLRGRKASLEELQSVHSERHVLLYGTNPLSRLKLDNGKLAGLLAQRMFVMLPCGGVGVDTDTIWNELHSSNAARWAAGSVTDLAFKVASRELKNGFAVVRPPGHHADHSTAMGFCFFNSVAIACRQLQQQS-KASKILIVDWDVHHGNGTQQTFYQDPSVLYISLHRHDDGNFFPGSGAVDEVGAGSGEGFNVNVAWAGGLDPPMGDPEYLAAFRIVVMPIAREFSPDLVLVSAGFDAAEGHPAPLGGYHVSAKCFGYMTQQLMNLAGGAVVLALEGGHDLTAICDASEACVAALLGNRVDPLSEEGWKQKPNLNAIRSLEAVIRVHSKYWGCMQRLASCPDSWVPRVPGADKEEVEAVTALASLSVGILAEDRPSEQLVEEEEPMNL-----------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "M9PHQ2-1", "uniprot_id": "M9PHQ2_DROME", "id": "M9PHQ2-1", "name": "histone deacetylase", "aln": "MSSPDDRIPIHDLPSEAGSDERLLHITPATLTLDFKPHPAVDIDQQIMELKKSQELQKQRLINSFQEQSKQMELEHKLQLEHKYQKQPTNKRFSLELIVIIQFAVNSHGAFQELRNESMVTAAAAAVAQEQHRQQLHQQQQQHQQQQQQQQHQQQQQQQQARGRDGMKLKQNCSANASPEVKQILNCFILSRKSQAAASNGTTTTSPYRNRGVVKSSSGESLPAGTVTSAHPYKIPQPPPSLLKYESDFPLRKTASEPNLLKIRLKQSVIERKARIGGPAGARRHERLLQAAQRRQQKNSVLTNCNSTPDSGPNSPPSAAALAVGVVGSRGSPTSAPIQEENEEGSQYQPGQRSSINDLPLFSSPSLPNISLGRPHLPNSAQAHAQVNAQVAAQAQAQAQAQAQAHAMFAALAAAQGGCGQPGYYNPLGMAFVGRQPAPLAMIPATGIAPQQPSPVVRSASATSTSSSQASLVGDVAPPQAHAASTILPSSSSYMQQLGSVAGSGVNLHAAAVAAAAAAAAAAGSLPPTNSHGHGHGSHAHPHPHAHGHGHGHGHGIYAGHQHNVPITDAQVAQVHLHKQGHRPLGRTQSAPLPLGHPMLTGAVQLNVVQTHYENSEAERQAYEHQVVNQKVRQTVLTRSGAAAAAAAAAGVSVVREAQLKEEDDDSAAEVMDLTDKKKPPKTVLTSTIATSTSQNLPEALAAAAAAAAYRAPHNASSNSASATKSGIKLRDQEYLQQQREQLLLLQQEEELAKSLMRPLSRTLSSPLVPLGPHGLSQIPDTGQQPAPIATSSSADHIPPVNLSLPHRQHRQLMSTLYASQLRNHQPSASGSPPHKVTTGLAYDPLMLKHSCICGDNAQHPEHSGRLQSVWARLNETDLVKRCDRLRARKATQEELQTVHTEAHAMLFGSNQCQLSRPKLENTL----SASFVRLSCGGLGVDLDTTWNEHHTATAARMAAGCVIDLALKTAKGDLRNGFAVVRPPGHHAEANLAMGFCFFNSIAIAAKLLRQRMPEVRRILIVDWDVHHGNGTQQAFYQSPDILYLSIHRHDDGNFFPGTGGPTECGSGAGLGFNVNISWSGALNPPLGDAEYIAAFRTVVMPIARSFNPDIVLVSSGFDAATGHPAPLGGYHVSPACFGFMTRELLQLANGKVVLALEGGYDLAAICDSAQECVRALLGDPAAPIAKAELERPPCQNAINTLQKTIAIQQTHWPCVRMLEHTVGLSALETLKVEHDESETINAMAGLSMQSMHRTLSRDDSEEPMDQDETK----------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "A0A8M6Z193-1", "uniprot_id": "A0A8M6Z193_DANRE", "id": "A0A8M6Z193-1", "name": "", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------MSHHQQHRTLERGRRSTQEDKLSLR---KESEQTGAGCSLSVRRKLYEYICNKQHRTSAGQDIQQRELDRQ-----------------------------------EEDNPLRRTASEP-ILKLRSKRSMTGRQN--------------------------------------PLQRKTSAPPAVGDPDS-------------------------------------------------------MAVSASSATVSSLDNQMNRQELIQTTTYSASSG-----------------KEDSPLQIS--------IQHPVLWPAYAATAYN---------------------PQVFTLYPHIFTVTG--------------------QQWPPMP---------------------------------------------------HRPLIKSQSAPSYIQQYTHIHTPAYTLVQP----------MYQQQWPQETFQQHTLPEKVSVGPAWPES-----------------------------------------------PGDLGRFRKRTSEEVRISSQSPLESCNRQGVQLKEN---------------LEWRHKIFHQQVSRVHS-------------FPDT-----------------------------------FDTRLSSHSASALDMRKPNFTTGLVYE--MMKHRCDCRDSSCGLHEADRVTSIWSRLQECGLRSQCKLLKGRSATVEELLSVHSEELVCFFTGPEPYRS------------------------QMDIGTMWKNPRNSEALKMAVGSVTELALCVARGDLRNGFAVVTPPGHHASRSQTLDSIVFNSVAIAAKQLQEQL-KVKKILIVDWDVHHGSGTESIFYTDPSVLYISLHRYDDGAFFNGTGDPSRVGCDVGRGYNVNVAWSGGLRPPMGDAEYLAAFRTVVMPIAHEFSPNVVLVSAGFDAAEGHPAALGGYRVSPKCFGWLTQKLMELAEGRVVLVLEGGYELVSLCDASQACVSALLGNEPEPLSEVELLRSPCANAVCSLEKVLHVQSLHWRSVRSMLNTVSLSYVKAERRVSAGSEAALVLSGLNMTVPHR---RQLPNEPVEDDETHSTVSFTRRTFSFQSRS", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . . : :. : : : ..: .* .* *:: * * .:: : .. ***:*.*** : :. *: * :*. :: : :. :: :. . : . . . ", "identical_positions": 15, "similar_positions": 43, "identity": "1.16%" }, { "cls_id": "homologset.agr.MGI:1891836", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9NPJ1-1", "uniprot_id": "MKKS_HUMAN", "id": "Q9NPJ1-1", "name": "Molecular chaperone MKKS", "aln": "MSRLEAKKPSLCKSEPLTTERVRTTLSVLKRIVTSCYGPSGRLKQLHNGFGGYVCTTSQSSALLSHLLVTHPILKILTASIQNHVSSFSDCGLFTAILCCNLIENVQRLGLTPTTVIRLNKHLLSLCISYLKSETCGCRIPVDFSSTQILLCLVRSILTSKPACMLTRKETEHVSALILRAFLLTIPENAEGHIILGKSLIVPLKGQRVIDSTVLPGILIEMSEVQLMRLLPIKKSTALKVALFCTTLSGDTSDTGEGTVVVSYGVSLENAVLDQLLNLGRQLISDHVDLVLCQKVIHPSLKQFLNMHRIIAIDRIGVTLMEPLTKMTGTQPIGSLGSICP-NSYGSVKDVCTAKFGSKHFFHLIP-NEATICSLLLCNRNDTAWDELK---LTCQTALHVLQLTLKEPWALLGGGCTETHLAAYIRHKTHNDPESILKDDECTQTELQLIAEAFCSALESVVGSLEHDGGEILTDMKYGHLWSVQADSPCVANWPDLLSQCGCGLYNSQEELNWSFLRSTRRPFVPQSCLPHEAVGSASNLTLDCLTAKLSGLQVAVETANLILDLSYVIEDKN", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9JI70-1", "uniprot_id": "MKKS_MOUSE", "id": "Q9JI70-1", "name": "Molecular chaperone MKKS", "aln": "MSRLEAKKPSLCKTEPLTSEKVRSTLSVLKGVIASCYGPSGRLKQLHNGLGGCVYTTSQSSALLRNLSVTHPVLKILTSSVQNHVSCFSDCGLFTAILCCNLIENIQRLDLTPATAIKLNKYLLSLCTSYLKSEACSCRIPVDFRSTHTFLSLVHSILTSKPACMLTRKETDHIGALILKAFLLTIPESTEERMVLGKSIIVPLKGQRVTDSTVLPGLLIEASEVQLRRLLPTQKASGLRVALFCTSLSGDFSNAGEGVVVAHYQVSLENAVLEQLLNLGRRLVTDHVDLVLCQKVIHPSLKQFFSERHVMAIDRVGVTLMESLSKVTGATPIGSLNPIVS-TTYGSVKDVCSARFGSKHFFHLLP-NEATVCTLLLCSRNDTAWEELK---LTCQTAMHVLQLTIKEPWVLLGGGCTETHLAAYVRHKVHHEAEAIVRDDGCTQAKLHVAAEAFCSALESVAGSLEHDGGEILIDTKYGHLWSCQADSASVGNWSDTLSRCGCGLYNSQEELSWSVLRSTYHPFAPQTCLPQAALGSASNLTVDCFTAKLSGLQVAVETANLILDLSYVIEDKN", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8M9QNB5-1", "uniprot_id": "A0A8M9QNB5_DANRE", "id": "A0A8M9QNB5-1", "name": "", "aln": "MSRISKKKPALCTDEPLSNSTICQKITLLRNILSTAYGPTGRLKQIHNNVGGHVLTTSTSTALLKRLEMSEPLLKLISTALQHHTTRYSDSGLFMGIFTLTLIENTKKYGLRTSTAIKVYKHLVEQCNVYLKGDSCGCKVPVEFSSCDSLVALAHSMITSKPACMLDSRETQQISSLITQAFLYSIPCNSSGTACFGRTVTIGIEGQSVNHSSVFPGLLLDVPEMLLPGDLERLGDGPFKVVLFGVSLSGDISEVGDVALEVHRGLNPERDLLQQLLKIGEQVVKDKVSLFACQKVVHPVLQHYLREHEVVVIERLGLALMEPFAKITGARAVASLFSLVPMEAYGLVAGLCFQDCGSKKLLQLLSSKHAAISTMVLCHRNETMLEELKVCAMTCQRAEHVLRLTLREPYALLGGGCTETQLATHITHMNQSTAPTTAAALGISHSEFLMAVESFRSSLLAVALSLEHDGQDCLIDLTYGHRWVMDISS-----QTEVKHTCGCGLLEDRSNLEKTHLNTACQTFSPVFLENNDTQP----KVLDSFSAKLNALNVAVEMASLVLDVKYIIKDVN", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "***:. ***:**. ***:.. : .:::*: ::::.***:*****:**..** * *** *:*** .* ::.*:**::::::*:*.: :**.*** .*: .**** :: .* .:*.*:: *:*:. * ***.::*.*::**:* * . ::.*.:*::******** :**:::.:** :*** :** .:. :*::: : ::** * .*:*:**:*:: .*: * * ::*.** .:**** *:.*: .: . :. *. :*:***::*.:::.*:*.*. ****:** *:::: :.::.*:*:*::***.::*:**: .:.** .: . :** * .:* ***::::*:. :.*::.:::** **:* :*** :*** * ***:**::**:.*********:**::: * : . : ::::: : .*:* *:* :*. ****** : * * .*** * : .* .: ***** :.:.:*. : *.:: :.* * : : .:*.::***..*:**** *.*:**:.*:*:* *", "identical_positions": 214, "similar_positions": 222, "identity": "37.22%" }, { "cls_id": "homologset.agr.MGI:1891837", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9VS66-1", "uniprot_id": "Q9VS66_DROME", "id": "Q9VS66-1", "name": "Peptidase M14 domain-containing protein", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MKFSLGLLVLFLGATLVA-----------------------AEQDYEGYRIYEVIPST--ADQADLLHQLSLQG--YDFIS---------------ETRLLGHPSRVIVSPAQLKHFQQLVEAEKMTLTLVNSNLGASIAEEFAQRQMQRLLAPITGK----------GRLSTERYYTHEEIINYIDDLAQRFPSRVFVKTVGWSYEQRVLKTITITNGD---GKANKKVIFMDGGFHAREWISPAAVLYVIDQLVEQFEE--------------NAHLLKDYDWVILPLVNADGYEHTQTGTLARMWRKTRQPYTYAGQTCYGADPNRNFDFHW-NEEGASSNPCADTYAGPTAFSEPETITVRDLMHSL-AD--RGIMYLTLHSYGNYLLYPWGWT-SDLPENWEDLDAVARTGAEAIENAT---GTVYTYG-SSTNVLYIAAGA--SDDYGYYAG-FNVSITMELPGAGSIG----FNPPVTRIDEFVTETWIGIRAMAEKVIEMY---------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VS67-1", "uniprot_id": "Q9VS67_DROME", "id": "Q9VS67-1", "name": "Peptidase M14 domain-containing protein", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MTVVWVILALSCLSLSAGLQR-----------------------TNK-YEGYKIYEVSSEARSVAFSEALSELVKNASYYEVFS---------------ELN-AGNPGKIMVHPHEQVNFVQLMEENNVKYDIINRNVGLTLSRQFETNRMLRHWFPYNG------------RLGTERYYNHEEINQFIEDLAGEHPRRVFLKTVGRSYEGRWLKTITITNGD---ARRNKNVILVDGGFHAREWISPAAATYLINQLVYNLED--------------NADLLLDFDWVILPVVNPDGYEYTQLSEDTRMWRKTRKPSSSD---CIGTDPNRNFDFHW-NEEGASDDPCDNIYAGAKPFSEPEALVVGDLIHSY-VD--RGQMYLTLHSYGSLILYPWGWT-AAVPDTEEDLHEVAAAGQSAIQEAT---GTIYKIGPSATTINYAASGA--SDDYAFNAG-FPISFTMELP-FGGTG----FDPPASDIDSIVKETWVGIAAMARKVIQKYPLA------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VS65-1", "uniprot_id": "Q9VS65_DROME", "id": "Q9VS65-1", "name": "Peptidase M14 domain-containing protein", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MRNYHLEYKVLIEDLAPLVHAQRAENLRKKLLIQWPHI----------DVLSA--FYTHSEINDYLDSLLERFPKRVQVKQFGWSYERRPLKVLTITNGD---GRRNKPVILIDGTVHAREWISPSMALYIIQQLLDNYGD--------------NQELLQDYDWVIMPVVNADGYEYTHT--DSRYWRKSRRPTSNP--ECIGTDINRNFGYEWGHDEGSSSDPCENIYRGERPFDQSESQVLRDVMLHY-KG--RLNFYLSLHSYGNYFLLPWGYT-SDFPDTYQDMMSVADAGAKAIIYST---NGIYSYG-STYYVLYPTSGD--TTDFAFGVVNATVAMTMELPAAGFQG----FDPWISQIERLVTESWVGVRAMAAEVIRRYPS-------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VS80-1", "uniprot_id": "Q9VS80_DROME", "id": "Q9VS80-1", "name": "Peptidase M14 domain-containing protein", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MWKILCGIVVLVTIVVNQLSEAREVRRRRGLMLQLDN------------------YLSYDGIMQYLDELALSHSNRVTLKDVARTYENRALKMAIITNGD---GRPGKRVIFLDAALHSREWMTPAAALLTIHKLVVEFAE--------------NSDLLTDYDWHIMPLANPDGYEYSRN--TERYWRNTRTPNGGN---CFGTNLNRNFAVDWNVGFPELKDPCDENYAGSSPFSEVEARTVRDIMHGL-VESKRAVMYLSLHTANRSVFYPWVYD-TDPVSNQKEHDEIGRFVADRILQST---GTFIKTWQYAKYAG-TFGGT--SMDYALLAG-FPLSFVFEMSGTGRDHVEYKFFPPARDIRHLAEESWTGIKAFAEKTIEKYPPSRVISYNPMVKLAENAATRNLGFNSMVATVCLFFTYLTNCNFF", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VL86-1", "uniprot_id": "CBPA1_DROME", "id": "Q9VL86-1", "name": "Zinc carboxypeptidase A 1", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSLNKCLLFALLAIVASASVSAE-----------------------RVRYDNYRMYKVNSEN--AKQLEVLKDLEGSSDSIMFLD---------------GVHLVGADIQIIVAPHKVPDFLEILGKSEIKYELQSRDVQKSLDEIDEKVA-----IKGRAT----------TAYNWAQYYELDDTYAWLQSLAQTNPGVVTLIEGGKTYQGRSILGVKITKGGETINGKAKPGIFLEAGIHAREWIAPAAATFIINQLLTSEVEN-------------IKELAENYTWYVLPHANPDGYVYTHT--TNRLWRKTR--TPYG--SCFGADPNRNWGFHWNEV-GASSSACSDTYAGPSAFSEIETLSLSKFIEG---LKGKVQLYLSLHAYSQYLLYPYGHT-SDLPDNVADFEKVFDASIAAVNKR----YGTTYTGGNIYDAIYPAAGA--SVDWAYGTQDVRMAFCYELRPSSTSYLT-GFKLPAEQIVPASEELLDSIVAMATEVKSLGYFD------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VL87-1", "uniprot_id": "Q9VL87_DROME", "id": "Q9VL87-1", "name": "Peptidase M14 domain-containing protein", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MKLLLLLLSVNILIFCLAE-----------------------RQRFDNYKVYRVSPVK--ANQLEGLRSLEANSEDALVLN---------------NLHLG--PTDFLVAPDFDGTFLKLVKDLDLSPELIDANAQTSLSLDIEPIA-----DANRRS----------DDYSWSEYHELNDTHRWMQNLVGKYPDVVSVFVAGQSYEGRELLGLRINHND---GRAEKQSIFLEAGMHAREWIGPATATYFANELLSSQQQE-------------IMNLARSYVWYILPHANPDGYVYTHK--TNRMWRKTR--SPQDK-NCVGTDPNRNWDFHWREV-GASSDPCSESYAGPKAFSEPEVQTLSQFLKS---VPEPMFMFLSLHSFSQLLLYPYGHT-SALPENHRQLEQIFNTAVGAMKRR----YGTRYTGGNVYDAIYPAAGS--SMDWAYGVLNVKYSFTYELRPSGYSFWT-GFRLPAAQIIPTGQETTDSLVEMIKAAAQIEGYKIE----------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q0E9F9-1", "uniprot_id": "Q0E9F9_DROME", "id": "Q0E9F9-1", "name": "Zinc carboxypeptidase A 1", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MGN------------KIINMPAARIGTQWLVILCVAMAASG-TNLDSGICPVAGDSGCRGNPPD-----QARYDNYRIYNVEFEN--QEQIELFQKLEEQSDSLTFIG---------------HAREVGQKLSILVAAHRVADIADLLKTYKVKHRVLTYNFQEKIDRNLAEVQ-----PESIDA----------SQLDWQHFFHLKTIYEWLDKMVEKYPNRVTVLDMGSSTQGNAIKGVKLTS-N-----ANNKAIFIESGIHAREWISPAAATYIINQLLTSQDPK-------------VQQLAQDYNWIIFPCVNPDGYKYTFE--HDRMWRKNR--QLFG--TCRGVDLNRNYPDHWNST-GSSSDPTRYDFAGPSAGSELETKRLIDFIRAN-AGKEQIKTYIALHSYSQMLMFPYGYT-KERVSNYDDLQEFGKKASAAIKAE----NGRDYVSGSLFETIYPSSGG--SMDWAHSEAGIPIAYTFELR-GPPDSQD-LFILPAVEIQPTASEAFTAIRAIVEAAAEKGYYK------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VCM8-1", "uniprot_id": "Q9VCM8_DROME", "id": "Q9VCM8-1", "name": "Zinc carboxypeptidase A 1", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MYACQSALQENEMEIFYTDFKLRRIKMLPKGGTPKTWLLLLLVSSVCVIQESKASSFCTKADQCALDEEIKTAADSVQARYDHTRIYQVELAS--EEHVRLFQALEQASDSCSFMG---------------HARQPGQKLTIMVTGAKVADFDDLVHSYNVTHRVLNYNFQALIDANYLEVA-----PEDTKP----------EEFDWKRYHPLESINAWLKKLAETHP-EVLLVELGVSAQGRPILGVQIAFDN-----ENRTTVFVESGIHAREWIAPATATYIIDQLVNSKDSA-------------VQALARSQRWYIFPTVNPDGYQYTFK--GDRMWRKNR--ALFG--ICRGVDLNRNFPFHWNVT-GASGDPCRYDYSGPSAASEVETQRMIEFIRHR-VESERIRTFISLHSYSQMIMFPYGHS-AERVDNYHDLTDIGKLAANKIKDV----SGRIYKSGSIYETIYPSSGG--SKDWAHGQLKIPITFSYELR-GPADSED-LFILSAKEIEPTAAEAFASIQTIVQEAGKRGYYQ------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VLZ2-1", "uniprot_id": "Q9VLZ2_DROME", "id": "Q9VLZ2-1", "name": "Zinc carboxypeptidase A 1", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MRLLWLLATLVALTSAGILKDSP----------------------KERYDNFRVYKLTIQN--KIQLAAIEKIGELTKKYNIWK---------------EYDERSRQIDIMVSPGELNHFQELLKFNNISSELMIENVQERIDEEQVTPT-----ADS-------------ATFGWTKYYELEEIEAWLDEILNAYPSVTEEFIVGKSYEGRTIRGIKISHKA------GNPGIFIESNIHAREWITSASATWFINQLLTSEDAD-------------VRSLADNYDWHIIPVFNVDGFEYSHK--KDRMWRKTRQPHA-TN-ACIGADANRNFDSYWLQNNGASDNPCSETFAGDNPESEPEAKALVEYLTK---IQDQISVYISFHSYGQYLLSPYGHTNEEFPENYNDILTIGKAFADAIEALP---YGTVYQYGSTADVLYVATGT--SVDWVFNELGKKIGYTIEYR---DKGRY-GFILPPVQIIPNCEELMVGMLALIEKTKELGYL-------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VLZ1-1", "uniprot_id": "Q9VLZ1_DROME", "id": "Q9VLZ1-1", "name": "Peptidase M14 domain-containing protein", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MALNSLPIVLALVVLAQGASFGQDE----------------------RLRYDNYSVYKVKFET--QAQRSILRKLAEDRENFRLWH---------------EAKD---ELHLMLSPGAFGELETEIQKTNVTAELFISNVQELIDSEEAANL-----KASRD-----------GTFGWTKYNSLAEIYAWLDDILAAYPTITESFIVGQSYEGRTIRGIKISYKS------NNPGVLIESNIHAREWITSATATWLINEFLTSTDEL-------------VRDLAENHDWYIVPVLNVDGFVYTHE--KDRMWRKTRQPSE-IS-SCIGADPNRNYDSHWMENEGASSNPCAEDYGGPKPFSEPEIQAMSEFVIS---IKDKINVLLAFHSYSQLLLSPYGHTKEEFPPNFDDMMEVAKAYGDAVESLP---YGTVYRYGSAAGILYPASGA--TIDWAYNEQGVEISYTIEFR---DTGRY-GFILPPVHIIPNAEEALIGIAALLEKCKDLGYLGLKSAL-------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VRZ3-1", "uniprot_id": "Q9VRZ3_DROME", "id": "Q9VRZ3-1", "name": "Zinc carboxypeptidase A 1", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MLLKILLVVGLFGLARSVE----------------------QVRYDNYKVYNVRIDD--LEQFKLLHTQ-ERSLKLSSWR---------------EARHLGESSDIMLPPEYQKTFESLLTKHNFTYNLKIDNVQTHIDAQRPKQR-----ITS---------------MEWTQFHTLEEIYAWLDVIEDRYPDIVTPFTIGNSYEGRPIRGVKISYKE------GNPAVFIESNIHAREWITSATITYFIDELLVPRNPA-------------VRDIAQNVDWYIIPVLNTDGFAYSHE--VERLWRKSRLPSDPTG-ECIGTDLNRNFDYLWMLT-GAESDPCSQLYAGPSPESDPEISQLTAYINNS-IPEGTIKIYISLHSYGQYVLSPWGHTALEFPEHYPQMMHVAKGFSDALYRR----YGTVFTYGSSATTLYEVSGS--GKEWAYAVKNIKIHYTIELR---DKGEL-GFVLPPEDIIPVAREVTEGFVGMIAAAREIDIL-------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9W478-1", "uniprot_id": "Q9W478_DROME", "id": "Q9W478-1", "name": "Peptidase M14 domain-containing protein", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MTQKTMLLQLLLLVAAVA----ASLANEL----------------------PSNLTLLDANEIP------QRYDEAQLWRIYNISEAMQKRVPVGQMLEQKFGGNIWKENSKFLDISIARDQLKAARSFLSAHRLDPQILSHNIQSMIDEELLEGIQSSSFGHGRRTKKA-----ARSSMHWKDYHDLETIYSFMREIRTKFPNIVRLYTIGQTAEGRDLKVLRISEN-----PRENKKVWIDGGIHAREWISPATVTFILYQLMSDWE--------------NQPAHIRGLTWYIMPVMNPDGYEYSRT--TNRLWRKNRSPSRRAQ--CSGVDLNRNFDIG-WNGYGSSTNPCSDTYRGSAPASERETRAVAEFLAKR---KYNLESYLTFHSYGQMIVYPWAYK-AVKVKDASVLQRVSSLAAERILQK----TGTSYRAAVTHEVLGIAGGG--SDDWSRAALGVKYVYTIELRDRGAYG----FVLPPRFIKDTALEGWTVVETVAQAIGP--------SSSG-----------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9W475-1", "uniprot_id": "Q9W475_DROME", "id": "Q9W475-1", "name": "Peptidase M14 domain-containing protein", "aln": "MYNARSRGSAANEGISPKRIVTIGSLLLVLGLNQVASMSLDRLALERNELPADQQQQQQQDVLVDNMKLTSIPSADSSDMYMLVPDTVASQLEDTEHVNRNSIEADPESDPSGSSSSDMLMLESDSSPAMQLVELPSDITVAESQPETEHDTENDQQQPESIEEHVVLMKPASQEAQLEQTVDLATEAAPVPLNDELPEDEESPAATESAVEELEKESEAAMDDQVPEESEIQPEQVQPGEYQSESDGEQAETKPEIEAQPEVEAQPEAEAQPEAEPQLEVEPQPEVESQPEVESQPEVEAQPEVEPQSEVESQPEAESHSEPETQAEVEAQPEVESLPEAESQPEAESQPEREPEVEAEKISDNEVDTTEASLMETLVEGIEDGLTAAMDNLVPEELAEASDKQETELESEDQQSPVTEAIEEQAVPEIEQEKEKEPEQITLADETEQDSAQPSNEEPVEIAPEQHTEAEIAPAKIPEEGKPEEEVQVEEESKPVEESKPEEEIKQQEDAKPEEDDQNYAETQPAVTEVKPEETPADIPVEIPAEVPAEIPAEIPAEVPAEIPAESPAEIAAEVPAEIPAEIPAEIPAETPAETHAEIPADVPAQVVAEAPAETPAETPAEVPAEIPSKVQDEIQSDSTQAEPQVEKEAQQPEKETKPLESSLLTTIIPMVMPQPQVPSQPLQVQDSVLNYVNASFMQQQ----------------------PSETDLPKTEEESPFNAHLRRYDGAQVWRIVVQTDKDKR---MADELQSKYDGQLWKEVKQEVDYLLKPQVLAAAERHIRAANLSRIVLIDNLQRVIEKENPPAEKIAELQN----RKG-----HR--LTWQAYHRLEDIHGFIDYMAKTYPDICSTEIIGYSVEKRPLKILKISNG-----NARNPGIWIDGGMHAREWISPATVTYIANQLVEGWE--------------DLPEHMRSINWYIHPVANPDGYEYSHT--TDRLWRKN-MRAHGRQ--CPGVDLNRNFGYK-WGGKGTSASPCSQTYRGSKAFSEPETFYISKFISGFP--RETFQAYLSFHSYGQYILYPWGYD-YQLTQDRADLDRVARQAGTSITKS----TGVKYTVGSSATTLYPAAGG--SDDWAKGIAGIKYAYTIEMGDTGRYG----FVLPARFIQYNGKDGVTFADTVARAIAQGRGKSVARNSSGSRRRGH-----------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9JHH6-1", "uniprot_id": "CBPB2_MOUSE", "id": "Q9JHH6-1", "name": "Carboxypeptidase B2", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MKLHGLGILVAIILY-EQHGFAFQSG----------------------QVLSALPRTSRQVQLLQNLTTTYEVVLWQPVTAEFIEKK---------------------KEVHFFVNASDVDSVKAHLNVSRIPFNVLMNNVEDLIEQQTFNDTVSPRASA----------------SYYEQYHSLNEIYSWIEVITEQHPDMLQKIYIGSSFEKYPLYVLKVSGK----EQRIKNAIWIDCGIHAREWISPAFCLWFIGYVTQFHGKEN-----------LYTRLLRHVDFYIMPVMNVDGYDYTWK--KNRMWRKNRSAHKNNR--CVGTDLNRNFASKHWCEKGASSSSCSETYCGLYPESEPEVKAVADFLRRN---IDHIKAYISMHSYSQQILFPYSYN-RSKSKDHEELSLVASEAVRAIESIN---KNTRYTHGSGSESLYLAPGG--SDDWIYDLG-IKYSFTIELRDTGRYG----FLLPERYIKPTCAEALAAISKIVWHVIRNT---------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9EQV9-1", "uniprot_id": "CBPB2_RAT", "id": "Q9EQV9-1", "name": "Carboxypeptidase B2", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MKLYGLGVLVAIILY-EKHGLAFQSG----------------------HVLSALPRTSRQVQLLQNLTTTYEVVLWQPVTAEFIEKK---------------------KEVHFFVNASDVNSVKAYLNASRIPFNVLMNNVEDLIQQQTSNDTVSPRASS----------------SYYEQYHSLNEIYSWIEVITEQHPDMLQKIYIGSSYEKYPLYVLKVSGK----EHRVKNAIWIDCGIHAREWISPAFCLWFIGYVTQFHGKEN-----------TYTRLLRHVDFYIMPVMNVDGYDYTWK--KNRMWRKNRSVHMNNR--CVGTDLNRNFASKHWCEKGASSFSCSETYCGLYPESEPEVKAVADFLRRN---INHIKAYISMHSYSQQILFPYSYN-RSKSKDHEELSLVASEAVRAIESIN---KNTRYTHGSGSESLYLAPGG--SDDWIYDLG-IKYSFTIELRDTGRYG----FLLPERFIKPTCAEALAAVSKIAWHVIRNS---------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q96IY4-1", "uniprot_id": "CBPB2_HUMAN", "id": "Q96IY4-1", "name": "Carboxypeptidase B2", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MKLCSLAVLVPIVLFCEQHVFAFQSG----------------------QVLAALPRTSRQVQVLQNLTTTYEIVLWQPVTADLIVKK---------------------KQVHFFVNASDVDNVKAHLNVSGIPCSVLLADVEDLIQQQISNDTVSPRASA----------------SYYEQYHSLNEIYSWIEFITERHPDMLTKIHIGSSFEKYPLYVLKVSGK----EQAAKNAIWIDCGIHAREWISPAFCLWFIGHITQFYGIIG-----------QYTNLLRLVDFYVMPVVNVDGYDYSWK--KNRMWRKNRSFYANNH--CIGTDLNRNFASKHWCEEGASSSSCSETYCGLYPESEPEVKAVASFLRRN---INQIKAYISMHSYSQHIVFPYSYT-RSKSKDHEELSLVASEAVRAIEKIS---KNTRYTHGHGSETLYLAPGG--GDDWIYDLG-IKYSFTIELRDTGTYG----FLLPERYIKPTCREAFAAVSKIAWHVIRNV---------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "E7F897-1", "uniprot_id": "E7F897_DANRE", "id": "E7F897-1", "name": "", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MRALIQLAYFICFSIFLETCLCKVKHD----------------------QVLAITVSSQEHVEKVQNLTSHNETALWQPASPNYITTN---------------------SEVHLYIQSTSVQFVKEHLREHAITFRVLVENTAALVAMQIRNDTSDPRSGG----------------VFYERYHSLEDIYYWINKTSREHSDMVKVILIGSSSEKRPLYVLKLSGKR---EEEVNRAMWMDCGIHAREWIAPAFCMWFVNYALAFYNQNT-----------EITEMLNKMDIYILTVMNPDGYKYTWT--TDRMWRKNRSENKDSY--CAGVDLNRNFDAN-WCTKGASDDPCDPTYCGQFPESEPETQAVAKFLRSH---KDTVKLYLSIHSYSQMLLFPYSCS-YNEIPNHNELFELVKEASTKIRRYY---RNN-YKYGSGAKTIYLAPGG--SDDWAYDLG-IKYSFTFELQDRGQYG----FLLPPSFIPQACNEALLAAKVIALHVINKTQ--------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P38836-1", "uniprot_id": "ECM14_YEAST", "id": "P38836-1", "name": "Inactive metallocarboxypeptidase ECM14", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MLHMNSLWGCFLFVLLAVTGAVQG---------------------LQEDYSEYAVYRFTSDN---YSTLVRDVIAPLTDDYDVWT----------------------RSNNFIDIKLPKEIGEQINDGQVIIDNMNELIQNTLPTSQMMAREQAVFENDYD-------------FFFNEYRDLDTIYMWLDLLERSFPSLVAVEHLGRTFEGRELKALHISGNKPE-SNPEKKTIVITGGIHAREWISVSTVCWALYQLLNRYGSSK-----------KETKYLDDLDFLVIPVFNPDGYAYTWS--HDRLWRKNRQRTHVPQ--CLGIDIDHSFGFQWEKA---HTHACSEEYSGETPFEAWEASAWYKYINET-KGDYKIYGYIDMHSYSQEILYPYAYSCDALPRDLENLLELSYGLSKAIRSKSGRNYDVISACKDRGSDIFPGLGAGSALDFMYHHR-AHWAFQLKLRDTGNHG----FLLPPENIKPVGKETYAALKYFCDFLLDPEI--------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "Q9VS64-1", "uniprot_id": "Q9VS64_DROME", "id": "Q9VS64-1", "name": "Peptidase M14 domain-containing protein", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MWQGIVCSLALCLVGLAGLGIANNLAGYEG-----------------YTKYTVQHGDENAFKYMVDLQTNDAELDFWLLTRNSSVLTVSP--------------RRKTQFEASLSSLGVSYEMQPLMELMAALQANSSFADDNYDGEYEECQQDECEQAERPRRRTRR--------QARGFFSHYPRYHEVLSFMSGLAARYPQFCRYESLGRSNEGRHIAALSISLNS---RVRPRRVAYIQAATHGREWITTQTVLYLAYELLSNLRAF--------------TRVLQDVEIFLVPLVNPDGYEYTHT--TDRFWRKNRHRYAGHS--CSGVDINRNFGNHWNYQ-GASQNLCSEVYSGTAPNSEPETSAVVRYLEFN---RNRVKLSLDVHSFGKFIFYPYGYAKNTVPPTVGTLRSVALRAANQIGRYR----GTRYTTGTSASILYEASGS--LDDFAYGNLGIPLSYTLELPGD-------EFHVPAHDIIHVCKETFAGFIEFIRHVSLY----------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9W477-1", "uniprot_id": "Q9W477_DROME", "id": "Q9W477-1", "name": "Peptidase M14 domain-containing protein", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MHRLPWKWAWLPLLLLITAKLEQVGGKTYLDWARTDSQLTRLPFFGGGVGHLLRYLHPLSMSPPSERGKISELRSELDANYVSYRGAQLWKLNFNATRGSSMAEREEDDEAAEKRQVLASPDAQFNEVVALFALTFVALIGSVFGQKLLLWRSVSVPEISGISGLPLALLTLNSSELYESTLEG------LQWLSPMDLRRFDFISPGSSYQINRRYRNGSQVQRYYGFQLWKVHETRLEQPE----LRAFWRHFGSEVWNINQDGIDILIEQRNVADARKFMDKVGYSYNIMIDDIESAIDESYVEVPAVEHPLDSVRNNSLPWMEVPGSTMNWRRYHDQADIKQFLQTLLETYSENVELIQIGVTRNKRPLEVIRVSNGN-----PDNWAVFVDAGLQARDWLSPAALTYAISKLTHLWGRPKGKDKGEGQRQSRAEKAMRRIDWYFLPLANPDGYQYSRQ--TDRLWTKNRGYDSVSG--CYGVNLDRNFDYGWDGT-GSTSNPCKNLYRGAHSFSEPESRAVCSFLSGM---REYLGAYVSLGGYGQAITYPWGDA-DYVTENQRNLKQTARRAVLALRRLN----QAEYSSGTSYRQKLARPGN--SADWVQDRIGPQLVFNMFLKDQGRYG----YLLPPHYIVESGEEVFEFLRIIAQQLQ------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : :: . . : : : : . : :.*:*: . . * **: :: * * :. * * : ::.: : * . . * : : . . . *: : * :: : * : . ", "identical_positions": 14, "similar_positions": 43, "identity": "1.13%" }, { "cls_id": "homologset.agr.MGI:1891838", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D4A2U2-1", "uniprot_id": "D4A2U2_RAT", "id": "D4A2U2-1", "name": "Zinc finger and BTB domain-containing protein 32", "aln": "MPQTPTRLISPYGSDRLVQLAARLRPALCDTLITVGGQEFLAHSLVLAGASPRLGCRGRWALVEGISPSTFAQLLTFVYGESVELQPGELGNLEEAARALGVQALEEACKRAQAAKNHEAGLDPGWKGHQ-QSE-FMRSSERGLGAPAERQTPEEESSSE-REQETPEEHKAPGESPEMAGGRARMR----GSEEALSPASMGYRGAETKQAEVMRGRASHRGSEESLRGCSSPLSPPGSLLTSLIPRPWWAEAPWLGEGQPALWSILLWPSRYGAPFSHSTPITAAWQVWPQDQRIPLTLNHCKGLWSENQLASSSPTPGSFPQGTEKLSPWEAEESGQGYTGTLATCVSQERRLNCPSHQHPPLPSPARSRPYSCSVCGKRFSLKHQMETHYRVHTGEKPFSCSLCPQRSRDFSAMTKHLRTHGAAPYRCPLCRAGCPSLASMQAHMRGHSPSRLPPGWTIRSTFLYSSSRPTRASISPGSPTSSAAT", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9JKD9-1", "uniprot_id": "ZBT32_MOUSE", "id": "Q9JKD9-1", "name": "Zinc finger and BTB domain-containing protein 32", "aln": "MPQTPTRLVSPYGSDRLVQLAARLRPALCDTLITVGGLEFPAHSLVLAGASPRLGCRGRWALVEDISPSTFAQILTFVYGESIELQPGELGDLEEAAKALGVQALEEACQRAQKGKDEDE-LDPGLKRHQ-QSEDFMRGSERGLGSPGEKQKPEKDFRSNGREQEMSHKHKAPGERPEMAG-ATRMM----SSE------------------EVMRGIESHKGSEESLRGCPDPLSPPGSLLTSLIPRPWWAEVPRLGEGQSALWSILLWPSRYGAPFSHSTPITAAWQVRPQDQRIPLTLNHSKALWSQNQLASSSPTPGSFPQGTESLSPWQIETSGQGFTGTLATCVSQERTLNCPSHQHPPLPSPARSRPYSCSVCGKRFSLKHQMETHYRVHTGEKPFSCSLCPQRSRDFSAMTKHLRTHGAAPYRCPLCRAGCPSLASMQAHMRGHSPSRLPPGWTIRSTFLYSSSRPTRASSSPGSPTSSAAT", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9Y2Y4-1", "uniprot_id": "ZBT32_HUMAN", "id": "Q9Y2Y4-1", "name": "Zinc finger and BTB domain-containing protein 32", "aln": "MSLPPIRLPSPYGSDRLVQLAARLRPALCDTLITVGSQEFPAHSLVLAGVSQQLGRRGQWALGEGISPSTFAQLLNFVYGESVELQPGELRPLQEAARALGVQSLEEACWRARGDRAKKP--DPGLKKHQEEPEKPSRNPERELGDPGEKQKPEQVSRTGGREQEMLHKHSPPRGRPEMAGATQEAQQEQTRSKEKRLQAPVGQRGADGKHGVLTWLRENPGGSEESLRKLPGPLPPAGSLQTSVTPRPSWAEAPWLVGGQPALWSILLMPPRYGIPFYHSTPTTGAWQEVWREQRIPLSLNAPKGLWSQNQLASSSPTPGSLPQGPAQLSPGEMEESDQGHTGALATCAGHEDKAGCPPRPHPPPAPPARSRPYACSVCGKRFSLKHQMETHYRVHTGEKPFSCSLCPQRSRDFSAMTKHLRTHGAAPYRCSLCGAGCPSLASMQAHMRGHSPSQLPPGWTIRSTFLYSSSRPSRPSTSPCCPSSSTT-", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*. .* ** ***************************. ** ********.* :** **:*** *.********:*.******:******* *:***:*****:***** **: : .. *** * ** :.* *..** ** *.*:*.**: : **** .:*..* ***** . *: : . ******* ..**.*.*** **: *** ***.* * **.******* *.*** ** **** *.*** ::*****:** *.***:************:***. .*** : * *.**.**:****..:* .**.: *** ..*******:********************************************************.** *******************:******************:*.* ** .*:**:: ", "identical_positions": 317, "similar_positions": 72, "identity": "64.69%" }, { "cls_id": "homologset.agr.MGI:1891839", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q63068-1", "uniprot_id": "PHAX_RAT", "id": "Q63068-1", "name": "Phosphorylated adapter RNA export protein", "aln": "-MALEAG--DMEEGQLSDSDSDMTVVPSDRPLQMAKVLGGG---------GAACAPVSNYRTVKHVDSSEESL-DSDDDCSLWKRKRQKCHSPPPKPEPFPFGQSGQK--PALNGGKKVN-------NIWGAVLQEQ--NQDAVATELGILGMEGTIDRSRQSETYNYLLAKKLAKKESQEYTKELDKDLDEYMHGDKKPGSKEEENGQGHLKRKRPVRDRLGNR--------VEMNYKGRYDITEEDSPEKVADEIAFRLQEPKKDLIARVVTILGNKKAIELLMETAEVEQNGGLFIMNGSRRRTPGGVFLNLLKNTPSISEEQIKDIFYIENQKEYENKK----AARKRRTQLLGKKMKEAIKSLN---------FQEDDDTSRETFASDTNEALASLDEAQEGPG------ETKLDAEDAIEVDHP---------------------------QDLDIF", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9JJT9-1", "uniprot_id": "PHAX_MOUSE", "id": "Q9JJT9-1", "name": "Phosphorylated adapter RNA export protein", "aln": "-MALEAG--DMEEGQLSDSDSDMTVVPSDRPLQMAKVLGGG---------SAACAPVSHYRTVKHVDSSEESL-DSDDDCSLWKRKRQKCHNTPPKPEPFPFGPSGQK--TALNGGKKVN-------NIWGAVLQEQ--NQDAVATELGILGMEGSIDRSRQSETYNYLLAKKLAKKESQEYTKELDKDLDEYMHGDKKPGSKEDENGQGHLKRKRPVRDRLGNR--------VEMNYKGRYEITEEDAPEKVADEIAFRLQEPKKDLIARVVRILGNKKAIELLMETAEVEQNGGLFIMNGSRRRTPGGVFLNLLKNTPSISEEQIKDIFYVENQKEYENKK----AARKRRTQLLGKKMKQAIKSLN---------FQEDDDTSRETFASDTNEALASLDEAQEGPG------ETKLDAEEAIEVDHP---------------------------QDLDIF", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9H814-1", "uniprot_id": "PHAX_HUMAN", "id": "Q9H814-1", "name": "Phosphorylated adapter RNA export protein", "aln": "-MALEVG--DMEDGQLSDSDSDMTVAPSDRPLQLPKVLGGDSAMRAFQNTATACAPVSHYRAVESVDSSEESFSDSDDDSCLWKRKRQKCFNPPPKPEPFQFGQSSQK--PPVAGGKKIN-------NIWGAVLQEQ--NQDAVATELGILGMEGTIDRSRQSETYNYLLAKKLRK-ESQEHTKDLDKELDEYMHGGKKMGSKEEENGQGHLKRKRPVKDRLGNR--------PEMNYKGRYEITAEDSQEKVADEISFRLQEPKKDLIARVVRIIGNKKAIELLMETAEVEQNGGLFIMNGSRRRTPGGVFLNLLKNTPSISEEQIKDIFYIENQKEYENKK----AARKRRTQVLGKKMKQAIKSLN---------FQEDDDTSRETFASDTNEALASLDESQEGHA------EAKLEAEEAIEVDHS---------------------------HDLDIF", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A1Z7P3-1", "uniprot_id": "A1Z7P3_DROME", "id": "A1Z7P3-1", "name": "Phosphorylated adapter RNA export protein", "aln": "MMELHANDVDLEDGELSESDDDGVYTPLQRPDGAEKVASPL----------TTCHQIQTALEDESQSNSDSSTAESSEDGCIKKLRTESTGPDGHKKRKKRIRRTVMRRVPPTDAEMQPNRARFKKYNVWASALQEDALSENMRGCDVTRSGRDRNVENYDFSLRYRLNGENTLKRRLSNSSEDGGECSHPAHKRGRPSSRPITGNQQRGLVKSRTGHRSRRGTSSASGSSDFCEPRHILDLNEVGERDPSDVATEMASKLYEEKDELLVRVVEVLGIDVCLELYKETQRIEADGGMMIKNGIRRRTPGGVFLFLIKHHDNITQEQQKRIFSEDRQSLSKSRKQIETLMRDRKVEELKKCLSKQVTELPTLNQRKEYYMQGDEQSEDKQPGSLSNPPPSPVGAEQEHDSPEYRTHEININLVDNAELPSTSKAAAAAQGAPLKDLISYDHDFLDVNCGDMDFF", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * *... *:*:*:**:**.* . .* :** ** . ::* :. : ..*:.* :*.:* .: * : :. * . : : : .. . : * *:*.:.***: .:: . :: * : .::. * *. :.* : *:. . : . : :* . . :: :* :* : :.* *. * .: : . * ..** *:: :* * *.:*:.*** ::* . .:** ** .:* :**::* ** ********** *:*: .*::** * ** :.*. :.:* *.*:.: * * :.: :..* :* *:::. : .* :* . :.:. ** . * ::: : *: . *:*:*", "identical_positions": 97, "similar_positions": 140, "identity": "20.95%" }, { "cls_id": "homologset.agr.MGI:1891840", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q56A27-1", "uniprot_id": "NCBP1_RAT", "id": "Q56A27-1", "name": "Nuclear cap-binding protein subunit 1", "aln": "--MSRRRHSYENDGGQPHKR---RKTSDANETEDHLESLICKVGEK--SACSLESNLEGLAGVLEADLP---NYKSKILRLLCTVARLLPEKLTIYTTLVGLLNARNYNFGGEFVEAMIRQLKESLKANN-------------YNEAVYLVRFLSDLVNCHVIAAPS--MVAMFENFVSVTQEEDVPQVRRDWYVYA-FLSSLPWVGKELYEKKDAEMDRIFSSTESYLKR---RQKTHVPMLQVWTADKPHPQEEYLDCLWAQIQKLKKDRWQER--------HILRPYLA---FDSILCEALQHNLPPFTPPPH---TEDSVYPMPRVIFRMFDYTDDPEGPVMPGSHSVERFVIEENLHCIIKSYWKERKTCAAQLVSY--------------------------PGKNKIPLNYHIVEVIFAELFQLPAPPHIDVMYTTLLIELCKLQPGSLPQVLAQATEMLYMRLDTMSTTCVDRFINWFSHHLSNFQFRWSWEDWSDCLTQDLE---SPKPKFVREVLEKCMRLS-YHQHILDIVPPTFSALCPANPTCIYKYGDESSNSLPGHSVALCLS---------------------VAFKSKATNDEIFSILKDVPNPNQVDDDDEGFRFNPLKIEVFVQTLLHLAAKSFSHSFSALAKFHEVFKTLAE-----SDKGKLHVLRVMFEVWRNHPQMIAVLVDKMIRTQIVDCAAVANWIFSSELSRDFTRLFVWEILHSTIRKMNKHVLKIQKELEEAKEKLARQHKRRSDDDDRGSDRK-------DGALEEQIERLQEKVESAQSEQKNLFLVIFQRFIMILTEHLVRCETDGTSILTPWYKNCIERLQQIFLQHHQIIQQYMVTLENLLFTAELDPHILAVFQQFCALQA", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q3UYV9-1", "uniprot_id": "NCBP1_MOUSE", "id": "Q3UYV9-1", "name": "Nuclear cap-binding protein subunit 1", "aln": "--MSRRRHSYENDGGQPHKR---RKTSDANETEDHLESLICKVGEK--SACSLESNLEGLAGVLEADLP---NYKSKILRLLCTVARLLPEKLTIYTTLVGLLNARNYNFGGEFVEAMIRQLKESLKANN-------------YNEAVYLVRFLSDLVNCHVIAAPS--MVAMFENFVSVTQEEDVPQVRRDWYVYA-FLSSLPWVGKELYEKKDAEMDRIFSTTESYLKR---RQKTHVPMLQVWTADKPHPQEEYLDCLWAQIQKLKKDRWQER--------HILRPYLA---FDSILCEALQHNLPPFTPPPH---TEDSVYPMPRVIFRMFDYTDDPEGPVMPGSHSVERFVIEENLHCIIKSYWKERKTCAAQLVSY--------------------------PGKNKIPLNYHIVEVIFAELFQLPAPPHIDVMYTTLLIELCKLQPGSLPQVLAQATEMLYMRLDTMSTTCVDRFINWFSHHLSNFQFRWSWEDWSDCLTQDLE---SPKPKFVREVLEKCMRLS-YHQHILDIVPPTFSALCPANPTCIYKYGDESSNSLPGHSVALCLS---------------------VAFKSKATNDEIFSILKDVPNPNQVDDDDEGFRFNPLKIEVFVQTLLHLAAKSFSHSFSALAKFHEVFKTLAE-----SDKGKLHVLRVMFEVWRNHPQMIAVLVDKMIRTQIVDCAAVANWIFSSELSRDFTRLFVWEILHSTIRKMNKHVLKIQKELEEAKEKLARQHKRRSDDDDRSSDRK-------DGALEEQIERLQEKVEAAQSEQKNLFLVIFQRFIMILTEHLVRCETDGTSILTPWYKNCIERLQQIFLQHHQTIQQYMVTLENLLFTAELDPHILAVFQQFCALQA", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q09161-1", "uniprot_id": "NCBP1_HUMAN", "id": "Q09161-1", "name": "Nuclear cap-binding protein subunit 1", "aln": "--MSRRRHSDENDGGQPHKR---RKTSDANETEDHLESLICKVGEK--SACSLESNLEGLAGVLEADLP---NYKSKILRLLCTVARLLPEKLTIYTTLVGLLNARNYNFGGEFVEAMIRQLKESLKANN-------------YNEAVYLVRFLSDLVNCHVIAAPS--MVAMFENFVSVTQEEDVPQVRRDWYVYA-FLSSLPWVGKELYEKKDAEMDRIFANTESYLKR---RQKTHVPMLQVWTADKPHPQEEYLDCLWAQIQKLKKDRWQER--------HILRPYLA---FDSILCEALQHNLPPFTPPPH---TEDSVYPMPRVIFRMFDYTDDPEGPVMPGSHSVERFVIEENLHCIIKSHWKERKTCAAQLVSY--------------------------PGKNKIPLNYHIVEVIFAELFQLPAPPHIDVMYTTLLIELCKLQPGSLPQVLAQATEMLYMRLDTMNTTCVDRFINWFSHHLSNFQFRWSWEDWSDCLSQDPE---SPKPKFVREVLEKCMRLS-YHQRILDIVPPTFSALCPANPTCIYKYGDESSNSLPGHSVALCLA---------------------VAFKSKATNDEIFSILKDVPNPNQDDDDDEGFSFNPLKIEVFVQTLLHLAAKSFSHSFSALAKFHEVFKTLAE-----SDEGKLHVLRVMFEVWRNHPQMIAVLVDKMIRTQIVDCAAVANWIFSSELSRDFTRLFVWEILHSTIRKMNKHVLKIQKELEEAKEKLARQHKRRSDDDDRSSDRK-------DGVLEEQIERLQEKVESAQSEQKNLFLVIFQRFIMILTEHLVRCETDGTSVLTPWYKNCIERLQQIFLQHHQIIQQYMVTLENLLFTAELDPHILAVFQQFCALQA", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q7K4N3-1", "uniprot_id": "NCBP1_DROME", "id": "Q7K4N3-1", "name": "Nuclear cap-binding protein subunit 1", "aln": "--MSRRRAHDTEDEGYDHRRNKRRRVSENQEIEDRLESLILRVGER--STSSVESNLEGLVSVLEADLG---TFRLKILRILSDCAVRMPEKCTVYTTLVGLLNAKNYKFGGEFVDHMVKTFKESLKMCR-------------WDAARYSLRFLADLVNCHVISATS--LLQLLDTMIDVSNEDTVPQVRRDWFVFA-VLSTLPWVGRDLYEKKESALESLLLRIEVYLNK---RSKKHHNALRVWSSDAPHPQEEYLDCLWAQIRKLRQDNWAEK--------HIPRPYLV---FDSILCEALQHNLPTIVPPPH---HDNFEYPMPWVVYRMFDYTDCPDGPNLPGAHSIERFLIEEHLHHIIETYHHERKDCAAQLLSF--------------------------PYKHKIPLEYCIVEVVFAELFHMPTPRYLDICYGSILIELCKLQPATLPQVLAQATEILFMRIDSMNTSCFDRFVNWFSYHLSNFKFTWSWDEWDSCLLLDGE---HPRPKFIQEVLQKCLRLS-YHQRITEMMPTTYAKLIPLTPVPNYKYANEEAANLPGTTVAHQLV---------------------VAIRQKCTPEEVVNILKDIPNSGYSGEEMSDGSFNALKIDVFVQTLLNLGSKSFSHSFAAISKFHSVFRALAE-----TEEAQICILHNIFELWSSHQQMMVVLIDKLLKLQIVDCSAVATWIFSKEMTGEFTKLYLWEILHLTIKKMNKHVIKLNTELSEAKEKLAKADSSSSDSEDDSSHKRKKPITHADKPSEEVVERMEEKLEAANVNQKRLFLIVFQRFIMILSEHLLRSDTDGRDPDTDWYRWTIGRLQQVFLMHHEQVQKYSSTLETLLFTSDLDTHILEVFQQFVALRA", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P34160-1", "uniprot_id": "NCBP1_YEAST", "id": "P34160-1", "name": "Nuclear cap-binding protein complex subunit 1", "aln": "MFNRKRRGDFDEDENYRDFRPRMPKRQRIPPVVQLCKEMMPDIRTIGESVKAFEDDIKFLSEAIMNEYGHEDYFNNALLSTLNAVVVEQPQKQAAIALLTMVVNSKNNVAGKSIINYFFEELQKWCKQTYNDEFKSTSNETGPWNKIKLILRFLSILSPMFLVDELINIYKSLFELSIELNNLDPGNRVPLSEAIYTNTLLNIPYL--FFFNRNNDGLRTKVEELLAYVEQNYLVKTTDINLLREYNGEPPYEMVELVRVVLPNVKKALINNLEQLNELFPDWNHLLTPQTGDEGFNDALTLPSVDDLKSFVRLNKNFGSVDSMWKTPRYAFHVYLPNSAGNFETVVPISTYAGQLFNDIIIDLVESLEFNRKEVARQVITLDLFFKAGIFTEPGESIAQLIATYEENPLAPTFKIEDLAIETILGLIFKLPSVSQPFAYFYTLLVDICQNSPKAIAPVFGRAFRFFYSHLDSLDFELKLRYLDWFSIQMSNFNFSWKWNEWEDDSIKFGKYFYNPKVNFAKNLIQKELRLTSNFSEVEDSLPQEFTKYLDTSYIPRDQLINYYQSLFTGYTVEEDSVRKNDLYFRQEGVPMENTVRKILDYTHKANNSREVTELESILGELKNEYGSIISDFNRFVIILLVQAVTDSGSRSLSHANKYINDLKEDLKTIFAKIELDIETKEYIIIEAVLTFWNANPQTGFLVADAFKYAGLLTSRTIFTFIFN-ETGLKNNGLIEATAIEAVFRNLSQQISEENESGNNFEFVFERLCTIANSTIDLLDVNA---------DEDIEIPKVNGEMDIDDIEDDKLDLKWKYFTVIGFIKSILRRYS---------------------HEYRELADKFIANIDNAIPHESTRRTISNWIQETKEV--", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :** :* . . * : . : :.:: : *. :.*.::: * .: : :. :* * . *:* : : *. ::*::* * .::: :.. ::: * :: :***: * .:: ::: :.:.: : :* . ::: * .:*:: :::::: : . *::: .... *: :..: *: * : : .:::* :. : *: * *:. * . .:* .:. : : : * :::: .. : : : :::: : :::: :** * *::: * .: :: :*.::. :*::*: : ::*:::*: .* ::. *:.:* .::: ::*::. *:::*** ::***:* *.*::*.. : *: :* :::::* :**: ...: : :* :: . : : :.* :* : *.. .. .. *:.: . ** : * ::**:: . .::*:**: : .::. :::: : : ::. :: .* : * :: * : :: . :: .:**. * . . * :. .::::.::: : : . .: : : : . .. * . . : : ::: ::: : ::..* * :: : : ::* : ::: ::: .::. : . * :*: : ", "identical_positions": 90, "similar_positions": 316, "identity": "10.04%" }, { "cls_id": "homologset.agr.MGI:1891883", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9Y426-1", "uniprot_id": "C2CD2_HUMAN", "id": "Q9Y426-1", "name": "C2 domain-containing protein 2", "aln": "--------------------------------MAMARLGSWLGEAQWLALVS--------------------------------------LFVAALATVGLYLAQWALARAR---------------------------------------PQPQRRAVEPGEGPRPGSDALLSWILTLGSWRSQWQAAWVTALNEEAER--KGGPPFLSFEEDPRQQALELVVQEVSSVLRSAEEKVVVCHVVGQAIQFLVSETPALGAG--CRLYDMRLSPFHLQLEFHMKEKREDLQISWSFISVPEMAVN--IQPKALGEDQVAETSAMSDVLKDILKHLAGSASPSVVLITKPTTVKEAQN-------LQCAASTAQESCPPKPPRAHELKLLVRNIHVLLLSEPGASGHINAVCVVQLNDPVQRFSSTLTKNTPDLMWEEEFTFELNAKSKELHLQISEA---GRSSEGLLATATVPLDLFKKQPSGPQSFTLTSGSACGSSVLGSVTAEFSYMEPGELKSWPIPPPVPAAKIEKDRTVMPCGTVVTTVTAVKTKPRVDVGRASPLSSDSPVKTPIKVKVIEKDIS----VQAIACRSAPVSKTLSSSDTELLVLNGSDPVAEVAIRQLSESSKLKLKSPRKKSTIIISGISKTS------------LSQDHDAALMQGYTASVDSTHQEDAPS---HPER--AAASAPPEE-----------------------------AESAQASLAPKPQEDELDSWDLEKE--PQAAAWSSQVLLDPDGDELSESSMSVLEPG------------------------TAKKHKGGILRKGAKLFFRRR----HQQKDPGMSQSHNDLVFLEQPEGSRRKGITLTRILNKKLLSRHRNKN------TMNGAPVEPCT-------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "E9Q3C1-1", "uniprot_id": "C2CD2_MOUSE", "id": "E9Q3C1-1", "name": "C2 domain-containing protein 2", "aln": "-------------------------------------MGSWLSEVQWLFLVS--------------------------------------LFVAALGTVGLYLAQWALAKAR---------------------------------------PPP-RRRAEPDELRRRESDTLLSWILTRDSWGNQWQAAWVTALNYEAEK--RGGPLRLSFQKDPRPQSLQLTVEKVSSVVKSTQEKVVICHVVGETLQFLVSAGPASATGSECQLYDVHLSPFHLKVEFHMEEKREDIQIRWSFTHVPETAIK--IQPQAPGEKQALGVNMLSEALEDLFKHLVNAASPSVFLSTKPTQVKEAQS-------LQCPSSTAQEPCPPKPPRAHELKLQVKNIRVSLINHPGASG-LSHVCVAQLNDPEQRFISTLVRNTTDLSWEEEFTFELNAKSKELVLQISQD---GCSSEGLLGIATIHLDLFRKQPNGPQTFRLISGTEPDSLVLGSVTAEFSYVEPGELKSWPAPPPVSAAKIEKDRTVMPCGTVVTTVTAVKTKPRFDTGRATPLNSESPVRTPVTVKVIEKDIS----VQAISCHSAPVSKTFSSSDTELLVLNGSDPVAEVAIRQLSESSKLKLKSPRKKSTIIISGISKTS------------LSQDHNAALMLDYAASMDSTNQGDATSALCHPEATEASATTPPEE-----------------------------NEPAQTLPALKPRENDLDSWELEKE--SPVASWSGPALQEPDGDELSESSLSTSELG------------------------AMKKHKGGLLRKGAKLFFRRR----HQQKDPGLSQSHNDLVFLQQPEGRQKKGATLGRLLNRKLLTRHRGKH------TMNGVPREPCI-------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "B7YZL3-1", "uniprot_id": "B7YZL3_DROME", "id": "B7YZL3-1", "name": "Protein kinase C-like 3", "aln": "MDLADQIDDYICSFEGLGDLTMDSLAIFIFLWAVLALFSVWLIKLLYHKYLNKDKSASAANSRQTSVAPTSGSPTSVAGKTEKRLSEPRDLLATKSKVEGLDLSKPLAGASGGRGRSSASPLNTAGAAAGGPRRRVVRQSSTGPENRKKRYVPPPSNVVGPETSSVTWTSQVFRWLYSDLVIVNELLMSWVIAINDTLRKSVEEHGVAVEVVRVLPDSPAPGLNNIFCNCDENNPADMLITFDCDAMPVLQVKTFRQKSGKVETSHYKVTVSRFRARMAIPMNYNSLKGEMRVEGYPDVRIAMNSVGAIKAMDQDEQQLQTVISDILTTALRDTIYPVDFSIYSTCPRAEVEPLDLPVIYPVHYDSLAHNMEQHMGGVGLRDSQHMVSGRRLLVKIVKGDGIRDAQNPYVVIEMDEPAQKNQTGTQR-GGKPFWDEHFLFELSPQSAEILFEVYDHPVIASDPPKFLGLGLVGIDELAVGPASTQLLQLQPRPYETQPVSGAITVDFVFIEGAEIPAGARPQRLKEALRLSTPAINEHIRNGADLADAAVRALQDGALSSSGSGGQPSKSTLIIHSVQRNSSSPNAFKVELNRDGQIEVTDTATELDQAVAQAFERAANEAQTELELELAKEEKSSQLGEPLIDSGNGTVNEESTAEFGQPNAASSPNGSSYHNNYSLNGNGNSNGAGSGGYNSLPRNGGAQQLAQQSGLLEGHDVVDDRGRSKKRNFFGTLKKRLSRSKTRTLSADQPNNNSHKSLSATNSNTTTATGFPRTATGTLNGDSSRSLSVDRATLSKSNSLGPRMGIGHSITDHSRRSSISESSAISGFSSASNKTYVHEASTLVLETIENGIKRHFIVPLAIAQRPRWRRKGTKLHIYNDHTFIAKHLSGSGLQCSICMKSIPRRPGKQGYECRDCQLISHKQCHIRAPQACPNPTVLSMELTSFPVLTERDINLVN", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :. ** : : :. *:.: . ** *:: . : * . . * :. :: *: : .: :** *:* .: . :.. . .. : ... .. .::: . . : *. . *.: :* *: :: : *: : . :: . . *:: :* .:.: . :*: * ::. ... *: : *: : :. : . :: * : : :.: * ::. * . . * ::::* *: : : . *:*.* ***..:* *: ::: : . .. :*. . : :* : * ..* : * . . . * *::*.:* ::* .*: : . * : * . :: : :: . .:. * . ::. .. .* ::.: :: :::: * .:. :.. :. * :::: : * :. : .*: * :*. . : **.: ..:* ** .... *. :.:: .*: . :.. : ... .: . :. . ::: * :*.::. .* . :. . .:.:. . :**. . *:. . : .. .*: . * :.:. : : *:.: . : : * ::** .* ::.::::* . *:. * .* ", "identical_positions": 83, "similar_positions": 280, "identity": "8.68%" }, { "cls_id": "homologset.agr.MGI:1891884", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I6APM8-1", "uniprot_id": "A0A8I6APM8_RAT", "id": "A0A8I6APM8-1", "name": "", "aln": "--------------------------------------------------MSTGQEARRDEGDSRKE-QEASIRDRAHLSQQRRLKQATQFLHKDSADLLPLDSLKRLGTSKDLQPHSVIQRRLVEGKQRRLQGESPLLQALIRGHDSSR-TSATQVPALLVNCKCQDQMLRVAVDTGTQHNQISAGCLRRLGLGKRVPQAPGGDLAPESTSQVEQVELELGQETVACSAQVVDVDSPEFCLGLQTLLSLKCCIDLDRGVLR---LKAPFS-----------ELPFLP-----------LYQE-----P---GQ--------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9JHR9-1", "uniprot_id": "NRIP2_MOUSE", "id": "Q9JHR9-1", "name": "Nuclear receptor-interacting protein 2", "aln": "--------------------------------------------------MSTGQEARRDEGDSRKE-QEASLRDRAHLSQQRQLKQATQFLHKDSADLLPLDSLKRLGTSKDLQPHSVIQRRLVEGNQRRLQGESPLLQALIRGHDSSR-TSATQVPALLVNCKCQDQMLRVAVDTGTQHNQISAGCLRRLGLGKRVPKAPGGDVAPEPPTQVEQLELELGQETVACSAQVVDVDSPEFCLGLQTLLSLKLATSLSASSLLPSALGIPTESICDSEALVPHSLLSLPKCTTKSLTEKDLQQMGSRLHPGCRGQSYLLPPLA", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9BQI9-1", "uniprot_id": "NRIP2_HUMAN", "id": "Q9BQI9-1", "name": "Nuclear receptor-interacting protein 2", "aln": "MLFIFPLSLPWRPSCWKESCSTGQRQAGRSREDSVTPPPSSPWPTPPAGAMSTKQEARRDEGEARTRGQEAQLRDRAHLSQQRRLKQATQFLHKDSADLLPLDSLKRLGTSKDLQPRSVIQRRLVEGNPNWLQGEPPRMQDLIHGQESRRKTSRTEIPALLVNCKCQDQLLRVAVDTGTQYNRISAGCLSRLGLEKRVLKASAGDLAPGPPTQVEQLELQLGQETVVCSAQVVDAESPEFCLGLQTLLSLKCCIDLEHGVLR---LKAPFS-----------ELPFLP-----------LYQE-----P---GQ--------", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *** ********::*.. ***.:**********:********************************:**********: . ****.* :* **:*::* * ** *::************:**********:*:****** **** *** :*..**:** ..:****:**:******.*******.:*************** . .*. . * * * . .* ** * * * ** ", "identical_positions": 168, "similar_positions": 38, "identity": "52.17%" }, { "cls_id": "homologset.agr.MGI:1891915", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D4A433-1", "uniprot_id": "D4A433_RAT", "id": "D4A433-1", "name": "", "aln": "------------MEPENKKSATEAAAIIDLDPDFEPQSRPRSCTWPLPRPELATEPPEPSE-VEPSLGQKVPTEGHSEP---TLLPSRLPEPAGGPQPEILGAVTGPRKGGSRRNAWGNQSYAELISQAIESAPEKRLTLAQIYEWMVRTVPYFKDKGDSNSSAGWKNSIRHNLSLHSKFIKVHNEATGKSSWWMLNPDGGKGGKAPRRRAASMDSSSKLLRG--RSKGPKKKPSVLPAPPEG-------------ATPRSPLGHFAKW---SSSPCPR-NREEADVWTTFRPRSSSNASTVSTRLSPMRP---ESEVLAEEEMPASASS--YAGGVPPTLSEDLELLDGLNLASP---------------------HSLLSR-SNLSSFSLQHPGLAG---------------------PLHSYGASLFGPIDGSLSAGEGCFSSSQSLEALLTSDTPPPPADVLMTQVDPILSQAP--TLLLLGGMPSSSKLATGVSLCPTPLEGP--GPSNLVP--------------TLSVMAPPP-----VMPGAPIP--KVLGTPVLASPTED----------------FSHDRMPQDLDLDMYMENLECDMDNIIS-DLMD-GEGLDFNFEPDP------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9WVH3-1", "uniprot_id": "FOXO4_MOUSE", "id": "Q9WVH3-1", "name": "Forkhead box protein O4", "aln": "------------MDPENKKSATGAAAILDLDPDFEPQSRPRSCTWPLPRPDLATEPHEPSE-VEPSLGQKVPTEGHSEP---ILLPSRLPEPAGGPQPGILGAVTGPRKGGSRRNAWGNQSYAELISQAIESAPEKRLTLAQIYEWMVRTVPYFKDKGDSNSSAGWKNSIRHNLSLHSKFIKVHNEATGKSSWWMLNPDGGKGGKAPRRRAASMDSSSKLLRG--RSKGPKKKPSVLPAPPEG-------------ATPRSPLGHFAKW---SSSPCPR-NREEADVWTTFRPRSSSNASTVSTRLSPMRP---ESEVLAEEEMPASASS--YAGGVPPTLSEDLELLDGLNLASP---------------------HSLLSR-SGLSGFSLQHPGLAG---------------------PLHSYGASLFGPIDGSLSAGEGCFSSSQSLEALLTSDTPPPPADVLMTQVDPILSQAP--TLLLLGGMPSSSKLGTGVSLCPTPLEGP--GPSNLVP--------------NLSVMAPPP-----VMAGAPIP--KVLGTPVLASPTED----------------SSHDRMPQDLDLDMYMENLECDMDNIIS-DLMD-GEGLDFNFEPDP------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P98177-1", "uniprot_id": "FOXO4_HUMAN", "id": "P98177-1", "name": "Forkhead box protein O4", "aln": "------------MDPGNENSATEAAAIIDLDPDFEPQSRPRSCTWPLPRPEIANQPSEPPE-VEPDLGEKVHTEGRSEP---ILLPSRLPEPAGGPQPGILGAVTGPRKGGSRRNAWGNQSYAELISQAIESAPEKRLTLAQIYEWMVRTVPYFKDKGDSNSSAGWKNSIRHNLSLHSKFIKVHNEATGKSSWWMLNPEGGKSGKAPRRRAASMDSSSKLLRG--RSKAPKKKPSVLPAPPEG-------------ATPTSPVGHFAKW---SGSPCSR-NREEADMWTTFRPRSSSNASSVSTRLSPLRP---ESEVLA-EEIPASVSS--YAGGVPPTLNEGLELLDGLNLTSS---------------------HSLLSR-SGLSGFSLQHPGVTG---------------------PLHTYSSSLFSPAEGPLSAGEGCFSSSQALEALLTSDTPPPPADVLMTQVDPILSQAP--TLLLLGGLPSSSKLATGVGLCPKPLEAP--GPSSLVP--------------TLSMIAPPP-----VMASAPIP--KALGTPVLTPPTEA----------------ASQDRMPQDLDLDMYMENLECDMDNIIS-DLMDEGEGLDFNFEPDP------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F1R3E6-1", "uniprot_id": "F1R3E6_DANRE", "id": "F1R3E6-1", "name": "", "aln": "------------MEEEN---------VPPIDPDFEPQTRPRSCTWPLPRPDISAVKAGGTDGSESAAGTPPAEEDKHDPQPIICDPEKIAVSEGGLVAGVGGAT--PRKGSSRRNAWGNQSYADLISQAIENSPEKRLTLAQIYDWMVKTVPYFKDKGDSNSSAGWKNSIRHNLSLHNKFLRVHNESTGKSSWWMLNPEGGKTGKAHRRRATSMDNSGKLLKSRIRAKQTKKQAGAAGIGGTGGGLQGEGTSGTGNADSPGPPGQFGKWGVNSSSPSSRGSLDDPDIWTSIRPRTSSNASTLSGRLSPIATGQEDEDDLPEDGLLGGYSSGNLPSTLPETLMEELDLIDGLTLMTAPQGGASPSMAPPAPPQPLPSASTLLPRGSSFPSFRQLQPTKASQGSTPPGPQSSVQPNAGSSTSSPSNFGNSLFSPLPGPGHSGFSTHVPS-SLEALLTSDSPPP-SDVMMTQMDPLMPSQGGGGLLGLGGSMSSSQVKAGQMMLSKGIDTSTVGQMSLQRPPQLQHSQMGFGMMHMAMSQEPPQL-STVKTQHQVPGSGLLHHGVIPSPAGNGGLQGLGQFSTMPCFIPSQDRLPTDLDIDMFTENLDCDVEYIINSDLMD-GDLVDFNFDPIIQGGQGYTGP--ATTQSSSHNWVPS", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q95V55-1", "uniprot_id": "FOXO_DROME", "id": "Q95V55-1", "name": "Forkhead box protein O", "aln": "MMDGYAQEWPRLTHTDNGLAMDQLGGDLPLDVGFEPQTRARSNTWPCPRPENFVEPTDELDSTKASNQQLAP----------------------GDSQQAIQNANAAKKNSSRRNAWGNLSYADLITHAIGSATDKRLTLSQIYEWMVQNVPYFKDKGDSNSSAGWKNSIRHNLSLHNRFMRVQNEGTGKSSWWMLNP-EAKPGKSVRRRAASMETSRYEKRR---GRAKKRVEALRQAGVVG-----------LNDATPSPSSSVSEG-LDHFPESPLHSGGGFQLSPDFRQRASSNASSCG-RLSPIRAQDLEPDWGFPVDYQNTTMTQAHAQALEELTGTMADELTLCNQQQQGFSAASGLPSQPPPPPYQPPQHQQAQQQQQQQSPYALNGPASGYNTLQPQSQCLLHRSLNCSCMHNARDGLSPNSVTTTMSPAYPNSEPSSDSLNTYSNVVLDGPADTAALMVQQQQQQQQQQQLSASLEGQCLEVLNNEAQPIDEFNLENFPVGNLECNVEELLQQEMSYGGLLDINIPLATVNTNLVNSSSGPLSISNISNLSNISSNSGSS--LSLNQLQAQLQQQQQQQQAQQQQQAQQQQQQHQQHQQQLLLNNNNNSSSSLELATQTATTNLNARVQYSQPSVVTSPPSWVH-", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . * :* .****:*.** *** ***: : :. * . .:*..******** ***:**::** .:.:*****:***:***:.***************************.:*::*:**.*********** .* **: ****:**:.* : .: *: . * . .* . ..: . .. . :: . :* *:*****: . ****: . : : : . : : : . : . . : :. . * . : . .* :*:: . * . : : . * * . . : :: * . : : . . :. :.. : .::: : : : :: : . : :: : : .. ::: :. ", "identical_positions": 116, "similar_positions": 126, "identity": "17.71%" }, { "cls_id": "homologset.agr.MGI:1891916", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q5U2T6-1", "uniprot_id": "PLAG1_RAT", "id": "Q5U2T6-1", "name": "Zinc finger protein PLAG1", "aln": "MATVIPGDLSEVRDTQKAPSGKRKRGESKPRKNFPCQLCDKAFNSVEKLKVHSFSHTGERPYKCTHQDCTKAFVSKYKLQRHMATHSPEKTHKCNYCEKMFHRKDHLKNHLHTHDPNKETFKCEECGKSYNTKLGFKRHLALHAATSGDLTCKVCLQTFESTGVLLEHLKSHAGKSSGGVKEKKHQCEHCERRFYTRKDVRRHMVVHTGRKDFLCQYCAQRFGRKDHLTRHMKKSHNQELLKVKTEPVDFLDPFTCNMSVPIKDELLPVMSLPSSELLSKPFTNTLQLNLYNTPFQSMQSSGSTHQMITTLPLGMTCPIDMDTVHPSHHLAFKCPFSSTSYAISIPEKEQPLKGEIESYLMELQGGAPSSSQDSQASSS-KLGLEPQSGSPDDGAGDLSLSKSSISISDPLNTPALDFSQLFNFIPLNGPPYNPLSVGSLGMSYSQDEAHSSVSQLPTQTQDLQDPANTVGLGSLHSLSAAFTSSLSSSTTLPRFHQAFQ", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9QYE0-1", "uniprot_id": "PLAG1_MOUSE", "id": "Q9QYE0-1", "name": "Zinc finger protein PLAG1", "aln": "MATVIPGDLSEVRDTQKAPSGKRKRGESKPRKNFPCQLCDKAFNSVEKLKVHSFSHTGERPYKCTHQDCTKAFVSKYKLQRHMATHSPEKTHKCNYCEKMFHRKDHLKNHLHTHDPNKETFKCEECGKSYNTKLGFKRHLALHAATSGDLTCKVCLQNFESTGVLLEHLKSHAGKSSGGVKEKKHQCEHCERRFYTRKDVRRHMVVHTGRKDFLCQYCAQRFGRKDHLTRHMKKSHNQELLKVKTEPVDFLDPFTCNMSVPIKDELLPVMSLPSSELLSKPFTNTLQLNLYNTPFQSMQSSGSAHQMITTLPLGMTCPIDMDAVHPSHHLAFKCPFSSTSYAISIPEKEQPLKGEIESYLMELQGGAPSSSQDSPASSS-KLGLEPQSGSPDDGAGDLSLSKSSISISDPLSTPALDFSQLFNFIPLNGPPYNPLSVGSLGMSYSQEEAHSSVSQLPTQTQDLQDPANTVGLSSLHSLSAAFTSSLSSSTTLPRFHQAFQ", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6DJT9-1", "uniprot_id": "PLAG1_HUMAN", "id": "Q6DJT9-1", "name": "Zinc finger protein PLAG1", "aln": "MATVIPGDLSEVRDTQKVPSGKRKRGETKPRKNFPCQLCDKAFNSVEKLKVHSYSHTGERPYKCIQQDCTKAFVSKYKLQRHMATHSPEKTHKCNYCEKMFHRKDHLKNHLHTHDPNKETFKCEECGKNYNTKLGFKRHLALHAATSGDLTCKVCLQTFESTGVLLEHLKSHAGKSSGGVKEKKHQCEHCDRRFYTRKDVRRHMVVHTGRKDFLCQYCAQRFGRKDHLTRHMKKSHNQELLKVKTEPVDFLDPFTCNVSVPIKDELLPVMSLPSSELLSKPFTNTLQLNLYNTPFQSMQSSGSAHQMITTLPLGMTCPIDMDTVHPSHHLSFKYPFSSTSYAISIPEKEQPLKGEIESYLMELQGGVPSSSQDSQASSSSKLGLDPQIGSLDDGAGDLSLSKSSISISDPLNTPALDFSQLFNFIPLNGPPYNPLSVGSLGMSYSQEEAHSSVSQLPPQTQDLQDPANTIGLGSLHSLSAAFTSSLSTSTTLPRFHQAFQ", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*****************.*********:*************************:********** :**************************************************************.****************************.********************************:******************************************************************:*********************************************:******************:*******:** ********************************.******* **** ****:** ** ********************.**********************************:**********.***********:**.**************:************", "identical_positions": 475, "similar_positions": 19, "identity": "95.0%" }, { "cls_id": "homologset.agr.MGI:1891917", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P35213-1", "uniprot_id": "1433B_RAT", "id": "P35213-1", "name": "14-3-3 protein beta/alpha", "aln": "-MTMDKSELVQKAKLAEQAERYDDMAAAMKAVTEQGHELSNEERNLLSVAYKNVVGARRSSWRVISSIEQKTERNEKKQQMGKEYREKIEAELQDICSDVLELLDKYLILNATHAESKVFYLKMKGDYFRYLSEVASGDNKQTTVSNSQQAYQEAFEISKKEMQPTHPIRLGLALNFSVFYYEILNSPEKACSLAKTAFDEAIAELDTLNEESYKDSTLIMQLLRDNLTLWTSENQGDEGDAGEGEN-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9CQV8-1", "uniprot_id": "1433B_MOUSE", "id": "Q9CQV8-1", "name": "14-3-3 protein beta/alpha", "aln": "-MTMDKSELVQKAKLAEQAERYDDMAAAMKAVTEQGHELSNEERNLLSVAYKNVVGARRSSWRVISSIEQKTERNEKKQQMGKEYREKIEAELQDICNDVLELLDKYLILNATQAESKVFYLKMKGDYFRYLSEVASGENKQTTVSNSQQAYQEAFEISKKEMQPTHPIRLGLALNFSVFYYEILNSPEKACSLAKTAFDEAIAELDTLNEESYKDSTLIMQLLRDNLTLWTSENQGDEGDAGEGEN-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P31946-1", "uniprot_id": "1433B_HUMAN", "id": "P31946-1", "name": "14-3-3 protein beta/alpha", "aln": "-MTMDKSELVQKAKLAEQAERYDDMAAAMKAVTEQGHELSNEERNLLSVAYKNVVGARRSSWRVISSIEQKTERNEKKQQMGKEYREKIEAELQDICNDVLELLDKYLIPNATQPESKVFYLKMKGDYFRYLSEVASGDNKQTTVSNSQQAYQEAFEISKKEMQPTHPIRLGLALNFSVFYYEILNSPEKACSLAKTAFDEAIAELDTLNEESYKDSTLIMQLLRDNLTLWTSENQGDEGDAGEGEN-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q5PRD0-1", "uniprot_id": "143BA_DANRE", "id": "Q5PRD0-1", "name": "14-3-3 protein beta/alpha-A", "aln": "---MDKSDLVQKAKLAEQAERYDDMAASMKAVTEGGVELSNEERNLLSVAYKNVVGARRSSWRVISSIEQKTEGNEKKQQMAREYREKIEAELQEICNDVLGLLEKYLIPNASQAESKVFYLKMKGDYYRYLSEVASGDSKRTTVENSQKAYQDAFEISKKEMQPTHPIRLGLALNFSVFYYEILNTPEQACSLAKTAFDEAIAELDTLNEDSYKDSTLIMQLLRDNLTLWTSENQGDEGDAGEGEN-", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q7T356-1", "uniprot_id": "143BB_DANRE", "id": "Q7T356-1", "name": "14-3-3 protein beta/alpha-B", "aln": "---MDKSDLVQKAKLAEQAERYDDMAAAMKAVTEGGVELSNEERNLLSVAYKNVVGARRSSWRVISSIEQKTEGNEKKQQMAREYREKIETELQDICSDVLGLLEKYLIANASQAESKVFYLKMKGDYYRYLSEVASGDSKATTVENSQKAYQDAFDISKKDMQPTHPIRLGLALNFSVFYYEILNSPENACQLAKTAFDEAIAELDTLNEDSYKDSTLIMQLLRDNLTLWTSENQGEE--AGENEN-", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P29310-1", "uniprot_id": "1433Z_DROME", "id": "P29310-1", "name": "14-3-3 protein zeta", "aln": "MSTVDKEELVQKAKLAEQSERYDDMAQAMKSVTETGVELSNEERNLLSVAYKNVVGARRSSWRVISSIEQKTEASARKQQLAREYRERVEKELREICYEVLGLLDKYLIPKASNPESKVFYLKMKGDYYRYLAEVATGDARNTVVDDSQTAYQDAFDISKGKMQPTHPIRLGLALNFSVFYYEILNSPDKACQLAKQAFDDAIAELDTLNEDSYKDSTLIMQLLRDNLTLWTSDTQGDEAEPQEGGDN", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :**.:**********:******* :**:*** * ************************************ . :***:.:****::* **::** :** **:**** :*::.*************:***:***:*: : *.*.:** ***:**:*** .************************:*::**.*** ***:**********:*********************:.**:* . *. : ", "identical_positions": 182, "similar_positions": 44, "identity": "73.39%" }, { "cls_id": "homologset.agr.MGI:1891924", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "E9PSU6-1", "uniprot_id": "PCX1_RAT", "id": "E9PSU6-1", "name": "Pecanex-like protein 1", "aln": "MGSQTLQILRQGVWAALSGGWYYDPHQATFVNALHLYLWLFLLGLPFTLYMALPSSMIIVAVYCPVVAAVFIVLKMVNYRLHRALDAGEVVDRSAN--EFTDQRAKAEQGNCSTRRKDSNGPSDPGGGIEMSEFIREATPP---VGCSSRNSYAGLDPSNQIGSGSSRLGTAATIKGDTDTAKTSDDISLSLGQSSSLCKEGSEEQDLATDRKLFRLVSNDSFVSIQPSLSSCGQDLPRDFSDKVSLPSHSQHHRVDQSLCSACDTEVASLVP----------LHSHSYRKEH-RPRGVPRTSSSA-VAFPDASLSGLP----------LYQQQQ---RRGLDPVTELDSSKPHSGTRESLVGQSCPLAQS---------QPAADRRKSYSQPPTK----------CGKSRA--------LNAEKSVDSLRSLS-------------------TRSSGSTESYCS--------------------------GTDRDTNSTLSSYKSEQTSSTHIESILS---------------EHDESPKVGDKSARKEGC-AESAEERCHGATDRRTSSDKTALEGSTPAGPPEAPDAQASEEKPDQVAPSSSASED--------------------ANKNPHANEFTV-------PGDRPPE--QSAESKEEQGEKPSLSTDSKVCKDDGGKQKEGD------------------VRPKSSSLIHRTTS---AHKPGRRRTGKKRASSFDSS---------RHRDYVSFRGVSGTKPHSAIFCHDE---------------------DSSDQSDLSRAPSVHSAHHFSSDSSSSATSHSCQSPEGKYSALKTKHGHKDRGTDSDHTHRAHPGPEGTAKKRASRRTSSTHSAKTRARVLSLDSGTVACLND---------------SNRLLAPDSIKPLTTSKSDLEAKEGEVLDELSLLG-RASQLETVTRSRNSLPSQVAFPEGEEQDAATGAAQASEEAVAFRRERSTFRRQAVRRRHNAGSNPTPPTLLIGPPLS-LQD--GQQGQQSTAQVKVQ-SRPPSQAAVLSASASLLVRKGS-----------VHLDASHDHASAVGGSSLHDELGKFSSTLYETGGCDMSLVNFEP---------------------------AARRASN-ICDTDSHVSSSTSVRFYPHDMLSLPQIRLNRLLTIDTDLLEQQDIDLSPDLAAT----------YGPTEEAAQKVKHYYRFWILPQLWIGIN---------------------------------------------FDRLTLLALFDRNREILENILAVVLAILVAFLGSILLIQGFFRDIWVFQFCLVIASCQYSLLKSVQPDSSSPRHGHNRIIAYSRPVYFCLCCGLIWLLDYGSRNL---STSKFKLYGITFTNPLVLLSARDLVIVFTLCFPIVFFIGLLPQVNTFVMYLCEQLDIHIFGGNATTSLLAALYSFLCSVVAVALLYGLCYGALRDSWDGQHIPVLFSVFCGLLVAVSYHLSRQSSDPSVLFSLIQSKIFPKTDEKNPEDP------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------LSEVKDPLPEKLSNSVSERLQSDLVVCVVIGVLYFAIHVSTVFTALQPALKYVLYALVGFVGLVTHYVLPQVRKQLPWHCFSRPLLKTAEHNQYEVRNAATMMWFEKLHVWLLFVEKNVIYPLIVLNELSSSADTIASPKKLDTELGALMITVAGLKLLRSSFSSPTYQYITVIFTVLFFKFDYEAFSETMLLDLFFMSILFSKLWELLYKLQFVYTYVAPWQITWGSAFHAFAQPFAVPHSAMLFVQAVVSALFSTPLNPFLGSAIFITSYVRPVKFWERDYNTKRVDHSNTRLASQLDRNPGSDDNNLNSIFYEHLTRSLQHSLCGDLLLGRWGNYSTGDCFILASDYLNALVHLIETGNGLVTFQLRGLEFRGTYCQQREVEAITEGVEEDEGFCCCEPGHVPHVLSFNAAFGQRWLAWEVVVTKYILEGYSITDNSAASMLQVFDLRRVLTTYYVKGIIYYVTTSSKLEEWLANETMQEGLRLCADRNYVDVDPTFNPNIDEDYDHRLAGISRESFCVIYLNWIEYCSSRR-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------AKPLDVDKDSSLVTLCYGLCVLGRRALGTASHHMSSNLESFLYGLHALFKGDFRISSVRDEWIFADMELLRKVVVPGIRMSIKLHQDHFTSPDEYDDPTVLYEAIVSHEKNLVIAHEGDPAWRSAVLANSPSLLALRHVMDDGTNEYKIIMLNRRYLSFRVIKVNKECVRGLWAGQQQELVFLRNRNPERGSIQNAKQALRNMINSSCDQPIGYPIFVSPLTTSYSDSHDQLKEILGGPISLGNIRDFIVSTWHRLRKGCGAGCNSGGNIE-------------DSDTGGGTSCPANSAT----TASDPHNSVPQGSTGHPGQGAGSGLHPPTTSYPPTLGTSHSAHSVQSS---------------------LVRQSPARASMASQSS-YCYG-SRHSSLRMSTTGFVPCRRSSTSQISLRNLPSSIQSRLSMVN----------QMEAASQGGMGCVQHGLPSSSSSSQSIPACK--HHTLVAFLGAEGSQSGATEAQPG---------------NTSSPATISHARKG-------------------EVVYRVQIVDLSQILEGINVSKRKELQWPDEGIRLKAGRNSWKDWSPQEGMEGHVVHRWVPCSRDPSTRSHIDKTVLLVQIDDKYVTVIETGVLELGAEV-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9QYC1-1", "uniprot_id": "PCX1_MOUSE", "id": "Q9QYC1-1", "name": "Pecanex-like protein 1", "aln": "MGSQTLQILRQGVWAALSGGWYYDPHQATFVNALHLYLWLFLLGLPFTLYMALPSSMIIVAVYCPVVAAVFIILKMVNYRLHRALDAGEIVDRSAK--EFTDQRAKAEQGNCSTRRKDSNGPSDPGGGIEMSEFIREATPP---VGCSSRNSYAGLDPSNQIGSGSSRLGTAATIKGDTDTAKTSDDISLSLGQSSSLCKEGSEEQDLATDRKLFRLVSNDSFISIQPSLSSCGQDLPRDFSDKVSLPSHSQHHRVDQSLCSACDTEVASLVP----------LHSHSYRKEH-RPRGVPRTSSSA-VAFPDASLSGLP----------LYQQQQ---RRGLDPVTELDSSKPHSGTRESSAGKSCPPAQS---------QPAADRRKSSSQPPTK----------CGKSRA--------LNAEKSVDSLRSLS-------------------TRSSGSTESYCS--------------------------GTDRDTNSTLSSYKSEQTSSTHIESILS---------------EHEESPKVGDKSARKRECGADSVEERSHRADDRRTSSDKTAPEGNTPAGPPEAPDAQASEEMADQAAPSSSASED--------------------ANKNPHANEFTV-------PGDRPPE--QSAESKEEQSEKPSLATDSRVCKDDGGKQKEGD------------------VRPKSSSLIHRTTS---AHKPGRRRTGKKRASSFDSS---------RHRDYVSFRGVSGTKPHSAVFGHDE---------------------DSSDQSDLSRAPSIHSAHQFSSDSSSSATSHSCQSPEGKYGALKTKHGHRDRGTDSDHTHRAHPGPEGTTKKRASRRTSSTSSAKTRARVLSLDSGTVACLND---------------SNRLLAPDSMKPLTTSKSDLEAKEGEVLDELSLLG-RASQLETVTRSRNSLPSQVAFPEGEEQDAATGAAQASEEAVAFRRERSTFRRQAVRRRHNAGSNPTPPTLLIGSPLS-LQD--GQQGQQSTAQVKVQ-SRPPSQAAVLSASASLLVRKGS-----------VHLEASHDHASAVGGSSLHDELGKFSSTLYETGGCDMSLVNFEP---------------------------AARRASN-ICDTDSHVSSSTSVRFYPHDMLSLPQIRLNRLLTIDTDLLEQQDIDLSPDLAAT----------YGPTEEAAQKVKHYYRFWVLPQLWIGIN---------------------------------------------FDRLTLLALFDRNREILENILAVVLAILVAFLGSILLIQGFFRDIWVFQFCLVIASCQYSLLKSVQPDSSSPRHGHNRIIAYSRPVYFCLCCGLIWLLDYGSRNL---TTSKFKLYGVTFTNPLVLLSARDLVIVFTLCFPIVFFIGLLPQVNTFVMYLCEQLDIHIFGGNATTSLLAALYSFLCSIVAVALLYGLCYGALRDSWDGQHVPVLFSVFCGLLVAVSYHLSRQSSDPSVLFSLMQSKIFPKADEKNPEDP------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------LSEVKDPLPEKLSNSVSERLQSDLVVCVIIGVLYFAIHVSTVFTALQPALKYVLYALVGVVGLVTHYVLPQVRKQLPWHCFSRPLLRTAEHSQYEVRNAATMMWFEKLHVWLLFVEKNIIYPLIVLNELSSSAETIASPKKLDTELGALMITIAGLKLLRSSFSSPTYQYITVIFTVLFFKFDYEAFSETMLLDLFFMSILFSKLWELLYKLQFVYTYVAPWQITWGSAFHAFAQPFAVPHSAMLFVQAIVSAFFSTPLNPFLGSAIFITSYVRPVKFWERDYNTKRVDHSNTRLASQLDRNPGSDDNNLNSIFYEHLTRSLQHSLCGDLLLGRWGNYSTGDCFILASDYLNALVHLIEIGNGLVTFQLRGLEFRGTYCQQREVEAITEGVEEDEGFCCCEPGHVPHVLSFNAAFGQRWLAWEVVVTKYILEGYSITDNSAASMLQVFDLRRVLTTYYVKGIIYYVTTSSKLEEWLANETMQEGLRLCADRNYVDVDPTFNPNIDEDYDHRLAGISRESFCVIYLSWIEYCSSRR-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------AKPLDVDKDSSLVTLCYGLCVLGRRALGTASHHMSSNLESFLYGLHALFKGDFRISSVRDEWIFADMELLRKVVVPGIRMSIKLHQDHFTSPDEYDDPTVLYEAIVSHEKNLVIAHEGDPAWRSAVLANSPSLLALRHVMDDGTNEYKIIMLNRRYLSFRVIKVNKECVRGLWAGQQQELVFLRNRNPERGSIQNAKQALRNMINSSCDQPIGYPIFVSPLTTSYSDSHDQLKEILGGPISLGNIRNFIVSTWHRLRKGCGAGCNSGGNIE-------------DSDTGGGTSCPGNSAV----TASDPHNNVSQGSTGHPGQGAGSGLHPPTTSYPPTLGTSHSAHSVQSS---------------------LVRQSPARASMASQSS-YCYS-SRHSSLRMSTTGFVPCRRSSTSQISLRNLPSSIQSRLSMVN----------QMEAASQGGMGCVQHGLPSSSSSSQSIPACK--HHTLVAFLGAEGGQGSATEAQPG---------------NTSSPANISHARKG-------------------EVIYRVQIVDLSQILEGINVSKRKELHWPDEGIRLKAGRNSWKDWSPQEGMEGHVVHRWVPCSRDPSTRSHIDKTVLLVQIDDKYVTIIETGVLELGAEV-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q96RV3-1", "uniprot_id": "PCX1_HUMAN", "id": "Q96RV3-1", "name": "Pecanex-like protein 1", "aln": "MGSQTLQILRQGVWAALSGGWYYDPHQATFVNALHLYLWLFLLGLPFTLYMALPSTMIIVAVYCPVIAAVFIVLKMVNYRLHRALDAGEVVDRTAN--EFTDQRTKAEQGNCSTRRKDSNGPSDPGGGIEMSEFIREATPP---VGCSSRNSYAGLDPSNQIGSGSSRLGTAATIKGDTDTAKTSDDISLSLGQSSSLCKEGSEEQDLAADRKLFRLVSNDSFISIQPSLSSCGQDLPRDFSDKVNLPSHNHHHHVDQSLSSACDTEVASLVP----------LHSHSYRKDH-RPRGVPRTSSSA-VAFPDTSLNDFP----------LYQQ-----RRGLDPVSELESSKPLSGSKESLVENSGLSGEF---------QLAGDLKINTSQPPTK----------SGKSKP--------LKAEKSMDSLRSLS-------------------TRSSGSTESYCS--------------------------GTDRDTNSTVSSYKSEQTSSTHIESILS---------------EHEESPKAGTKSGRKKEC-CAGPEEKNSCASDKRTSSEKIAMEASTNSGVHEAKDPTPSDEMHNQRGLSTSASEE--------------------ANKNPHANEFTS-------QGDRPPG--NTAENKEEKSDKSAVSVDSKVRKDVGGKQKEGD------------------VRPKSSSVIHRTAS---AHKSGRRRTGKKRASSFDSS---------RHRDYVCFRGVSGTKPHSAIFCHDE---------------------DSSDQSDLSRASSVQSAHQFSSDSSSSTTSHSCQSPEGRYSALKTKHTHKERGTDSEHTHKAHLVPEGTSKKRATRRTSSTNSAKTRARVLSLDSGTVACLND---------------SNRLMAPESIKPLTTSKSDLEAKEGEVLDELSLLG-RASQLETVTRSRNSLPNQVAFPEGEEQDAVSGAAQASEEAVSFRRERSTFRRQAVRRRHNAGSNPTPPTLLIGSPLS-LQD--GQQGQQSTAQVKVQ-SRPPSQAAVLSASASLLVRNGS-----------VHLEASHDNASAVGGSSLHDELGKFSSTLYETGGCDMSLVNFEP---------------------------AARRASN-ICDTDSHVSSSTSVRFYPHDVLSLPQIRLNRLLTIDTDLLEQQDIDLSPDLAAT----------YGPTEEAAQKVKHYYRFWILPQLWIGIN---------------------------------------------FDRLTLLALFDRNREILENVLAVILAILVAFLGSILLIQGFFRDIWVFQFCLVIASCQYSLLKSVQPDSSSPRHGHNRIIAYSRPVYFCICCGLIWLLDYGSRNL---TATKFKLYGITFTNPLVFISARDLVIVFTLCFPIVFFIGLLPQVNTFVMYLCEQLDIHIFGGNATTSLLAALYSFICSIVAVALLYGLCYGALKDSWDGQHIPVLFSIFCGLLVAVSYHLSRQSSDPSVLFSLVQSKIFPKTEEKNPEDP------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------LSEVKDPLPEKLRNSVSERLQSDLVVCIVIGVLYFAIHVSTVFTVLQPALKYVLYTLVGFVGFVTHYVLPQVRKQLPWHCFSHPLLKTLEYNQYEVRNAATMMWFEKLHVWLLFVEKNIIYPLIVLNELSSSAETIASPKKLNTELGALMITVAGLKLLRSSFSSPTYQYVTVIFTVLFFKFDYEAFSETMLLDLFFMSILFNKLWELLYKLQFVYTYIAPWQITWGSAFHAFAQPFAVPHSAMLFIQAAVSAFFSTPLNPFLGSAIFITSYVRPVKFWERDYNTKRVDHSNTRLASQLDRNPGSDDNNLNSIFYEHLTRSLQHSLCGDLLLGRWGNYSTGDCFILASDYLNALVHLIEIGNGLVTFQLRGLEFRGTYCQQREVEAITEGVEEDEGFCCCEPGHIPHMLSFNAAFSQRWLAWEVIVTKYILEGYSITDNSAASMLQVFDLRKVLTTYYVKGIIYYVTTSSKLEEWLANETMQEGLRLCADRNYVDVDPTFNPNIDEDYDHRLAGISRESFCVIYLNWIEYCSSRR-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------AKPVDVDKDSSLVTLCYGLCVLGRRALGTASHHMSSNLESFLYGLHALFKGDFRISSIRDEWIFADMELLRKVVVPGIRMSIKLHQDHFTSPDEYDDPTVLYEAIVSHEKNLVIAHEGDPAWRSAVLANSPSLLALRHVMDDGTNEYKIIMLNRRYLSFRVIKVNKECVRGLWAGQQQELVFLRNRNPERGSIQNAKQALRNMINSSCDQPIGYPIFVSPLTTSYSDSHEQLKDILGGPISLGNIRNFIVSTWHRLRKGCGAGCNSGGNIE-------------DSDTGGGTSCTGNNAT----TANNPHSNVTQGSIGNPGQGSGTGLHPPVTSYPPTLGTSHSSHSVQSG---------------------LVRQSPARASVASQSS-YCYS-SRHSSLRMSTTGFVPCRRSSTSQISLRNLPSSIQSRLSMVN----------QMEPSGQSGLACVQHGLPSSSSSSQSIPACK--HHTLVGFLATEGGQSSATDAQPG---------------NTLSPANNSHSRKA-------------------EVIYRVQIVDPSQILEGINLSKRKELQWPDEGIRLKAGRNSWKDWSPQEGMEGHVIHRWVPCSRDPGTRSHIDKAVLLVQIDDKYVTVIETGVLELGAEV-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M3BET8-1", "uniprot_id": "A0A8M3BET8_DANRE", "id": "A0A8M3BET8-1", "name": "Pecanex-like protein", "aln": "MGSQTLQILRQGVWASVTGGWYYDPHQNTFVNALHLYLWLLLLCLPFTLYMALPPTMVIVGIYCGVIAGMFVLLKAVNYRLHTALDEGEVVELRAKGSEGRGQGAERQREGTSTRQEDSNGPGDPGGGIEMSDFARDETPP---VDCSSRNSYVGMDSSHQITSHG-----ASVTNKRTGVGKAPDDISLSFAQS------CSQDQDLMSDPKMFCLVSNDSFASMQPSTS-----LAQDLYG-------STPHPFSQSLS-SCDTEITAHLS----------THSQSFRKESSRPRGLPRTSSSAGSAFPDPSLPEFS----------LYPPPR---RGGLDPVCEMDSSRSQRATESSEQADSGTPSTSGTECT--RYHLKEHRRLSRSVSRETGEGECAGEGGSGLYRSEGVQGGCERTGGHSAESLRSLS-------------------TRSSGSTESYCS--------------------------GTDRDTNSTLSSLHSEQTSSTHVESLLS---------------LSGD-------------------EKVNAGHADARNSN---------------------------------VASGE--------------------ANKNPHANELAIK-----LPTDDPPKSLNSESQQGEGTVEATSRTSADVSAGHQHQETEPDK-----------------VRPKTVNLVHRAASSSAATRSGRRRNGKQRASSFDAS---------RHREYICGRGMA--KPRSAVFMKGEE--------------------DSSDQSELSCASSLHSTHQLSTDSSS-STPHSCPSPEERRRPSLRAKMHGMPTSGQKVKEKERQKDKEKGKRRASRRTPSTGSAKTHARVLSLDSSTTACLND---------------PHHLGAPASSRPLTTSKSDLEAKEGEVLDAASLLG-RASQLESVTRSRNSLPCPISLSHTQDAMAGS-RAPGNDDTVTFRRERSTFRRQAVRRRHNAGSNSTPPASLIGSPLS-LQEALSQVSQASGSQVRGQPSRTPSQVTVLSTSASLLVRNGS-----------AQLEGCPDKASTVGVASLQDEFGKLTPPLYEVGGCDMSLVNFEP---------------------------ATRRASNNLWETDSHLSSSTSVRFYPHDLFSFPQMRLNRLLSMDPELLEQHDVDGSPDLQEAPHGTQDSTHNHPHTHALAHKTKQYYRFWLLPYLWVGLH---------------------------------------------FDRLTLLALFDRNREVLENLLSVALAVLVAFLGSVLLVHGFFTDIWVFQFCLVIASCQYSLLKSVQPDSSSPRHGHNRIIAYSRPVYFCLCCGLIWLLHYGSVNC---STNAVSLYGVALTSSVLLSQARDLLIVFTLCFPVIFFIGLLPQINTFVMYLLEQLDIHFFGGNACTSLLSALYSVLRSIVTIAMLYGFCYGALKDSWDPQHIPVLFSVFCGLLVAVSYHLSRQSSDPSVLISLVQSKVFPNVKDKNPEDP------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------LSEVQDPLPDKLRSSVNERLQSDVIVCVVIAVLYFAIHVSTVFIALQPFLSYVLYGLVGSVGLLTHYLLPQMRKQLPWYCFSHPLLKTREYYQFEIRGAAHVMWFERTHVWLLFVEKNILYPLIVLNELSGSAQELAGPKKLNTEIGALVITIAGLKLLRSSFSSPTYQYVTVLFTVLFFTFDYRQFSETMLLDLFIMSIIFSKLWELFYKLKFVYTYIAPWQITWGSAFHAFAQPFAVPHSAMLFVQAIVSAVFSTPLNPFLGSAIFISSYVRPVRFWEREYNTKRVDHSNTRLASQLDRNPGSDDNNLNSIFYEHLTRSLQHSLCGDLQLGRWGNYSTGDCFILASDYLNALVHLVEIGNGLITFQLRGLEFRGTYCQQREVEAITEGVEEDESCCCCEPGHLPHLLSFNAAFGQRWLAWEVLVTKYALEGYSITDNSAASMLQVFDLRRILTTYYVKGIIYYVIASPKLEEWLANEGLLEGLKSCGERNYVDLDPTFNPNIDEDYDHRLAGISRDSFCSVYLSWIQYCNSRR-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------EKPLDSEKDSLLVLLCYGLCVLGRRALGTASHHMSSNLESFLYGLHALFKGDFRISSVRDEWIFTDMELLRKVVVPGIRMSLKLHQDHFTSPDEYEESSVLFEAISSHEQTLVIAHEGDPAWRNAVLSNSPSLLALRHVLDEGTNEYKIIMLNRRYLSFRVIKVNKECVRGLWAGQQQELVFLRNRNPERGSIQNAKQALRNMINSSCDQPIGYPIYVSPLTTSYCNTHPQLGHILGGPISIANIRNFIVNTWHRLRKGCGAGCNSGGNVE-------------DCDAGGLSCGSGNSGN----SGTGASD--SQHSSGP------TALHAYT---PHSLGTSQSSQSVQSG---------------------LVRQSPARASVVSQSSSYRHSSSRQSSLRTSVTGLEPCRRSSSSQLSLRTLPTSLQLRLGTNS----------SIANPEPPG--------PSSSLSAHSIPPCKRHAHTLAGLLGNEALVLG-TDIHPHPHHHLHY------IHHHHHNPSLSCLRRD-------------------DISYRVQIVDVSQVLDVTNHPKRKELVWPDESMRLRSGRNFWREWTPLEGMEGHVVHRWVPCSRDPVSRSHIDKTILLVQVDDKLVPIIETGVIELGAEV-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P18490-1", "uniprot_id": "PCX_DROME", "id": "P18490-1", "name": "Protein pecanex", "aln": "MGSQTLEILRQGVWASLTGGYFYDPHQGVFCNVVHLYLWLYLLCSPFVAYLYFPSTWLTWCLYCVITSLTILMVKLANLALHRLYDRAQTMSEGNLKGQFVKVTKETEPRHDDEGGIEMKVIRPGGSRISGEQAINEASEENSIMSIDNVNSIIDLKVDVHRKNSSESIELMFYAPSMLSGGSQQDQQSLAGSASVSKSIRSTGPGGNSSTSAAAQADMFNKYLTVYPEVVEAAGSSAGSADGGSSGGDSRSGAAVSTLGHTGAGTAPAQHVRTGHLSRKCSEVFSRRHRRRLERQSSLDTAAAAANSNAENKLMRNQSDTIATAAPSFLHSQPTNKARGQTNPRQHFITSAPSTGIGGGDAPTSSTAVVVIAPASNSLVNPGRSSRLQRHRSSETHDERLKHQSRGGLFQP--ILQLPHHSAASSIGALAVLGGGGNVAANDVEDMELGLVRNAGSGGVADACSRALQSWILDPFPDGYLEDDSYTKSDLGIEQPHQPTFRTQHRHHHHHHHLHHHLGGAIIRKDPTSTMSALQLAAVTQPGTGGSVTGGGGAAGGGGSAAGMKRRRHSNATSYKHGSSQSNKSSLVGGGGSRGPSGEAGTSGGAGGTGGVRRIKSAALEVLCPQPSVSNLSPHPNSVEAISGQQQMRNPLPPPSKSLVRNQHLNLYPTQGYGDGTPSAGGGGPGNSSTCSSLFFGSSSACGSTTALIEPPVYPIVEHSDEKTAHEEHGDDCLGIGQGNADDDDEVDDVPIRRRTRALGCSQTHYSVESDVGGFLADEVGADEDVFKDFDDNLEHILSELQQTHNQLDDVLKTHDLHHHSHLHHHKAASVEGAGPSGGSVAVGVSAGNDDEDEETEDNNTGSRSPLLNDRNRQPATLREIQADKQLRQELSHQSGAVIPAPNPPVPIRSEADSGCPSSDCEQVSASSKDQLLSGIELELQQYQILQRCQLDEEQPCTSKMAAKSLGAIPKVVKYREVDELRRRR-RGGSPADAAEAGNEFALVKQTKQASRNSSSSNSTHSISLTDSLTADIHKMLWLMHGGAVDDRGRPITGTSADGTPIPASSSLVPPNMSNAHFQFYQDAIQALQGTHPTSGSSVEHMTNIELARDKLRLDAKLMCEQLVAAAEANSGVRGNTLATQQMTQQQVGMLMRGGSSSRHPSSAPFSVQGLINVIRSERPAARSQLDALQQLSDAAAALAANASEAASVSASGAGGGASSGGGGVLSALGLANHPSNQISQISQLSQMSQPMLNVDGHFAPYCDYWRPACLLSATEKPAAPKSFYKYRFKWCGQEHEFKIAMDRLELLALFDRDLHWMHVLLASLLCTLVACLGAAILQHDHYKDLCALLFCAVIAGAQYSLVKSVQPDAASPVHGFNKTVAYSRAIYFCLAGGMLLLLKRLDTDYGERTPDPVVFFGMRYSPADVVALLLQALYILLLCFPIIFSVGLCPQINTFLMYLLEQIDMHVFGGNAASSLLGSFLCVVRSVLAVMLLYGPLYGALDEQRGTQYI--LFSIFCAMLVPLGYHLSRCASDFSHLWRLIKTCIVSTYRDDEDEDLSQMQHIATGTVTGSGTANSTALQLTTSTPKQHRQTDVKTEHEQIELSSLEKLTVNEEHHEKDHGADDQLETDQDLPLQQKHSKSKTSSLGSSQQTLGKTISSSKRAITASSSCTSIGTGEPAVEAGALTEEAVEGEEQRRNTLAGEVGSKHELAENYDQAAKIDECEDKISSSSATNPGDMSTLTAGAGTATTDATPACLEADPDAEAEAPADEKQHQGILGTGTGTGTGTTEASENGSGGGANGNTNSNGTGNDLPDPLPRKLQATVTTRLKNDLVVMTLLAVSVLGLHCSTVFTALQPDLNVVLYSFIGVLGLLLHYIVPQMRKHMPWLCFSRPLLRQREFGQFEVLNAPKIMWFEKLYIYLSVLERNVLFPLLAISSLTADSQLIVA--KFGLPWGTLIVAICALKFVRNAYSDPTNQYLIIIFTVLLFRIDFAMATETFIIDYFFVSLAFRKCCDFLLKLQFIVTYIAPWQITWGSAFHAFAQPFSVPHSAMLFLQAAISAVLSTPLNPFLGSAIFLTSYVRPIKFWERDYNTRRIDHSNTRLSSQLERDLGADDNNLNSIFYEHLTRSLQHSLCGDLLMGRWGNVNQGDCFVLASDDLNCLVHIIELGNGLCTFQMRGLEFRGTYCQQREVEAITEDVEDNDGCCCCDPGHLPQLLSANAMFSTRWLAWQVVAAQYVIEGYSISDNLASATLQVFEYRKVLITYYIKSIIYYVVKNPKLEQWLASGPIQDALQHTLSRQFVDLDPIFNFNLDEDFDFRAVGITRSSFCYVYLKWINYCVDMRRDANSMGGAPPAQAPAAAGGASSAPATAGVAPPAPVTPAHNDSKSTPNLSAHGGQAGPSSGQSKSQSQQQLRRPQKSVAQETSVGGGGVVVGGTTVPGTGGVTGGGGDPQLSSSHSFANISRQTSESAPGLGGYVAYMDQNVFVKLAKSSTTTGAGAGAPTSRKESQEKPALRLKLASVGKDAPLVSLCLALGLLARRSLATASHSALTGVEFFLHGLHALFKGDFRITSPRDEWVFADMELLHSVVAPAVKMALKLQQDHITNPDEFLDPHALYDAIDNCSNELVISHEADPVWRSAVLRGAPNLLALRHVMEDGSDEYRIIRLTKRCLSFRVIKLNRECVRGLWAGQQQELIYLRNRNPERGSIQNAKQALRNIINSSCDQPIGYPIYVSPLTTSYADTNAQLCEVIGGAITLDTIRHTVLGWWHRIRERCRQGCSSGSALEPHPGSGPVQLGACNFGSGGSVVGAASTATGVGASTGSGLGVAAPGTAGSTGGESGDLAPVFISAPLYNTLTVNSYYSVRPGNVPGGPIPGNLGGNYVSDSLAVVRGGLAVMPVKPTSTTLIAGLLNRERDETSGSGIMGAGASGPTRATSSGGVRSRRPEVGSSRGRDHERRATLPIASGGAGGEPGKDLTAPQTQVEHEPSPRSTKLSSSSGSLGLGMGVGLGNIITTPGDYPRKTKGPICLTAVDTGTSSSAAEGKPAGSGTVAGTGVGGVIRKPRIEIFKKVIIVDDTGIYDCLDIID--AVVWPTERMRNNGGRLSWKDWEPSAGMVGHVVHCWTPNHKDIRFRSHVNRYVYLVEIGDHYVPVEELGLREYNQIMGSTEEMANSRRSSIQRDFHEYNIQLKLAGLAPIIGGGESSTATTSDASKSHKAKIRAVSSSSSEDEDTSSTRSIPLPQGDDGDLTNFTRLVSMWKEIILDNNKRRLYDMGELSPELLQKLDDAVQQQQQLEDALAEESKEKGTATVTANEGEEGVGEMEIEPEQEQKEVVYLEEQSPLEEVTVSKPDEQPAQPTIPASPVPAETSSTSSAKSTSSPSLCQEEEDAVDPEETPELASEESPSDENGESEAGTTV", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "******:********:::**::***** .* *.:****** ** **. *: :*.: : :** : : ::::* .* ** * .: :. : : : . : : *. *. .: .: : :. .. ** .:. . : . . . .. *: **: . * : . : :.: :: *. . . . .. ...* : : .*: .*: * .: ::::* : : . *: * :* .: :* . . . * : : . . . * :. .. * :* *. . .**.. . ** * :: :.*. : : .: *:. *. * *. *. :* .**.*.. ** . .: . .. . .. :.* ::.:: . . * * :..: * . * * . : :. . * .* .. :.:*. . . :. *: * ::. . .*. . : . .. . :.* . . : * : ** :*.:. : .. .. * : * :** :: ::*: .* :.. : .::* .::* : . :: . . ::. .* : .:: *:.:.**.* . * .. : ::. : : : ..:: : :.:*:**: : * *:. :.: : *:.: . * *: :. *. ::*:.*. ..:. :. * * .:. :. * : :: .: * .:. * : :. ::: .: :: :. :.:. :*** *******: . :. :*: *. *** **: :* :..: *: .: ** ***..****:******::** **.*: :****.:***:. *:: **. . : :. . ::*: : . :. : : :: ****::* :** **:***:*** **:*:*.***** :***.:: ..: *:::: :*** **** :. . *:: ***:**.:**.:.***** :** * * *::: :... :.: ** .:: **** ** :*. **:.*::* ::.* :.:* **** .*** *. *** ::* :*:: **::**:**::** ***:***: *. *:*: .*. :****: :::* .:*:*:::**:.:..*:..:: :.. *:. *:*::::..**::*.::*.** **: ::****:* :*: :**:::* *::*: * * ::: **:*: **:******************:********:** :**.:*************::*****::****:***:*:*******:***:*: *:************************* :***** . ****:**** **.***::* **** ***:********************.**:::. ***:***:*::** ** *. *****:*:.::* :*****:** *:: ****: *::* ***:*.***** ..***:***. : :.*: .*::**:** ** *:***:*.* .**:*.*** :**.**:** . * * . **: ** ** .* :*.**:*.**** :.:* **:************:* ****:*:*****:.**.*.::*::**:***:*.***: :. .*::** . .: ***:**.**.**.*** .:*.*******:::*::**:** *.:* *******:*:**************::********************:*************:********.::: ** .::**.*:: .**. ::. ***:*: * **.**. :* : .:** ..... : . . . : * . * :* **:.. :** . * .: . *: . .:. . * :*: . *..:: : * : .:. : * *.:. . .. * .. : .: . . * . .. : : :: :* *** : : : : . : ** * :* ..** *::* * ** ***:* *.* :* ***::: : **::.*: *.: * *: * . : ", "identical_positions": 749, "similar_positions": 727, "identity": "21.89%" }, { "cls_id": "homologset.agr.MGI:1891925", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P31943-1", "uniprot_id": "HNRH1_HUMAN", "id": "P31943-1", "name": "Heterogeneous nuclear ribonucleoprotein H", "aln": "--------------------------------------MMLGTEGGEGFVVKVRGLPWSCSADEVQRFFSDCKIQNGAQGIRFIYTRE-GRPSGEAFVELESEDEVKLALKKDRETMGHRYVEVFKSNNVEMDWVLKHTGPNSPDTANDGFVRLRGLPFGCSKEEIVQFFSGLEIVPN--GITLPVDFQGRSTGEAFVQFASQEIAEKALKKHKERIGHRYIEIFKSSRAEVRTHYDPPRKLMAMQRPGPYDRP--GAGRGYNSIGRGAGFERMRRGAYGGGYG---GYDDYNGYNDGYGFGSDRFGRDLNYCFSGMSDHRYGDGGSTFQSTTGHCVHMRGLP--YRATENDIYNFFSPLNPVRVHIEIGPDGRVTGEADVEFATHEDAVAAMSKDKANMQHRYVELFLNSTAGASGGAYEHRYVELFLNSTAGASGGAYGSQMMG------GMGLSNQSSYGGPASQQLSGGYGGGYGGQSSMSGYDQVLQE--------------------------------------------------------------------------NSSDFQSNIA----------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "O35737-1", "uniprot_id": "HNRH1_MOUSE", "id": "O35737-1", "name": "Heterogeneous nuclear ribonucleoprotein H", "aln": "--------------------------------------MMLGAEGGEGFVVKVRGLPWSCSADEVQRFFSDCKIQNGAQGIRFIYTRE-GRPSGEAFVELESEDEVKLALKKDRETMGHRYVEVFKSNNVEMDWVLKHTGPNSPDTANDGFVRLRGLPFGCSKEEIVQFFSGLEIVPN--GITLPVDFQGRSTGEAFVQFASQEIAEKALKKHKERIGHRYIEIFKSSRAEVRTHYDPPRKLMAMQRPGPYDRP--GAGRGYNSIGRGAGFERMRRGAYGGGYG---GYDDYNGYNDGYGFGSDRFGRDLNYCFSGMSDHRYGDGGSTFQSTTGHCVHMRGLP--YRATENDIYNFFSPLNPVRVHIEIGPDGRVTGEADVEFATHEDAVAAMSKDKANMQHRYVELFLNSTAGASGGAYEHRYVELFLNSTAGASGGAYGSQMMG------GMGLSNQSSYGGPASQQLSGGYGGGYGGQSSMSGYDQVLQE--------------------------------------------------------------------------NSSDFQSNIA----------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8VHV7-1", "uniprot_id": "HNRH1_RAT", "id": "Q8VHV7-1", "name": "Heterogeneous nuclear ribonucleoprotein H", "aln": "--------------------------------------MMLGAEGGEGFVVKVRGLPWSCSADEVQRFFSDCKIQNGAQGIRFIYTRE-GRPSGEAFVELESEDEVKLALKKDRETMGHRYVEVFKSNNVEMDWVLKHTGPNSPDTANDGFVRLRGLPFGCSEEEIVQFFSGLEIVPN--GITLPVDFQGRSTGEAFVQFASQEIAEKALKKHKERIGHRYIEIFKSSRAEVRTHYDPPRKLMAMQRPGPYDRP--GAGRGYNSIGRGAGFERMRRGAYGGGYG---GYDDYNGYNDGYGFGSDRFGRDLNYCFSGMSDHRYGDGGSTFQSTTGHCVHMRGLP--YRATENDIYNFFSPLNPVRVHIETGPDGRVTGEADVEFATHEDAVAAMSKDKANMQHRYVELFLNSTAGASGGAYEHRYVELFLNSTAGASGGAYGSQMMG------GMGLSNQSSYGGPASQQLSGGYGGGYGGQSSMSGYDQVLQE--------------------------------------------------------------------------NSSDFQSNIA----------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "F1QFJ8-1", "uniprot_id": "F1QFJ8_DANRE", "id": "F1QFJ8-1", "name": "", "aln": "------------------------------------------MADDEGFVVRVRGLPWSCSAEEVSRFFSGCKISSNGSAIHFTYTRE-GRPSGEAFVELESEDDLKIAVKKDRESMGHRYVEVFKSNNVEMDWVLKHTGPNCPETEGDGLVRLRGLPFGCSKEEIVQFFSGLEIVPN--GITLPVDFQGRSTGEAFVQFASQDIAEKALKKHKERIGHRYIEIFKSSRAEVRTHYEPPRKGMGMQRPGPYDRPS-GGGRGYNGMSRGGSFDRMRRGGYGG----------------------------------GVSDGRYGDGG-NFQSTTGHCVHMRGLP--YRATEPDIYNFFSPLNPVRVHIEIGPDGRVTGEADVEFATHEDAVAAMSKDKANMQHRYVELFLNSTAGGSN--------------------GGYGGQMMG------GMG--NQSSYG-HGGQQMGGGYTGGYSSQSSMGGYNDYNSQGG-----------------------------------------------------------------------MSNSYYGGSRGSVGMNGMGGGWGM---", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VGH5-1", "uniprot_id": "Q9VGH5_DROME", "id": "Q9VGH5-1", "name": "", "aln": "MSNADVQFNYGQQGNGDNFNDDSNQQQDEDDQYNEDGGGKIENVGESPKFVRLRGLPWSATHKEILDFLENVNVTNGSAGIHLVTSRVDGKNTGEAYVEVASQEDVEEARKLNKASMGHRYIEVFTATPKEAKEAMRKISGHG----TAFVVKLRGLPYAVTEQQIEEFFSGLDIKTDREGILFVMDRRGRATGEAFVQFESQDDTEQALGRNREKIGHRYIEIFRSSIAEMKRATGAGGG--VGGRPGPYDIRDRGANRGGNDFG-GGRNDWGNNGNFGVGANNMLGFNNLPSLMNSGNFGNNQGGNNGNFGNNSGPSNFGNFGGGNNGGNSGNFGNDSGNSGNFGNFGNNGGGNFGGNNNGGGGFNSGNNFNSPGGVNNFGNNGGSNFGGNGGGGFNNGGNFVSSSGVGNFGPIGGGRNNNNGNFGNSGFGNFGGNNNVGSNFGGGNNGGGGGFNNGSNFGGGNSMGGGGNFGPIGGGRGNDIEYYTIHMRGLPYTSFENDVFKFFEPIRPANVRINYNKKGLHSGTADAYFDTYEDSQVAMKRHREQMGSRYIELFYDGKTRGLNGGEHGGGNGGGGMGNNGGGNFSRRI", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . . .*::******.: .*: *:.. :: ... .*:: :* *: :***:**: *::::: * * :: :*****:***.:. * . .::: . : .*:*****:. ::::* :*****:* .: ** : :* :**:******** **: :*:** :::*:*********:** **:: . ****** *..** *.:. *. : ..* :* . .. . ** . ..:*: : * . : : . *. * :: * : . .* .: . . ... . . * .:*. .. * . . .. :* * * * *.:* . .*.: ..:.. * . ... . .. . ", "identical_positions": 106, "similar_positions": 139, "identity": "17.88%" }, { "cls_id": "homologset.agr.MGI:1913063", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9JJW5-1", "uniprot_id": "MYOZ2_MOUSE", "id": "Q9JJW5-1", "name": "Myozenin-2", "aln": "MLSHSAMVKQRKQQASAITKEIHGHDVDGMDLGKKVSIPRDIMIEELSHFSNRGARLFKMRQRRSDKYTFENFQYESRAQINHNIAMQNGRVDGSNLEGGSQQGPSTPPNTPDPRSPPNPENIAPGYSGPLKEIPPERFNTTAVPKYYRSPWEQAIGSDPELLEALYPKLFKPEGKAELRDYRSFNRVATPFGGFEKASKMVKFKVPDFELLLLTDPRFLAFANPLSGRRCFNRAPKGWVSENIPVVITTEPTEDATVPESDDL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A0G2KAQ5-1", "uniprot_id": "A0A0G2KAQ5_RAT", "id": "A0A0G2KAQ5-1", "name": "", "aln": "MLSHSAMVKQRKQQASAITKEIHGHDVDGMDLGKKVSVPRDIMIEELSHFGNRGARLFKMRQRRSDKYTFENFQYETKAQINHNLAMQNGRIDGSNLEGGSQQAPSTPPNTPDPRSPPNPENIAPGYSGPLKEIPPERFNTTAVPKYYQSPWEQAIGDDPELLEALYPKLFKPEGKAELPDYRSFNRVATPFGGFEKASKMVKFKVPDFERLLLTDPRFLAFANPLSGRRCFNRTPKGWISENIPVVITTEPAEDVTMPESDDL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9NPC6-1", "uniprot_id": "MYOZ2_HUMAN", "id": "Q9NPC6-1", "name": "Myozenin-2", "aln": "MLSHNTMMKQRKQQATAIMKEVHGNDVDGMDLGKKVSIPRDIMLEELSHLSNRGARLFKMRQRRSDKYTFENFQYQSRAQINHSIAMQNGKVDGSNLEGGSQQAPLTPPNTPDPRSPPNPDNIAPGYSGPLKEIPPEKFNTTAVPKYYQSPWEQAISNDPELLEALYPKLFKPEGKAELPDYRSFNRVATPFGGFEKASRMVKFKVPDFELLLLTDPRFMSFVNPLSGRRSFNRTPKGWISENIPIVITTEPTDDTTVPESEDL", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "****.:*:*******:** **:**:************:*****:*****:.************************:::*****.:*****::***********.* **************:****************:**********:*******..********************* *******************:********** ********::*.*******.***:****:*****:******::*.*:***:**", "identical_positions": 224, "similar_positions": 36, "identity": "84.85%" }, { "cls_id": "homologset.agr.MGI:1913066", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q71F54-1", "uniprot_id": "SH3R1_RAT", "id": "Q71F54-1", "name": "E3 ubiquitin-protein ligase SH3RF1", "aln": "MDESALLDLLECPVCLERLDASAKVLPCQHTFCKRCLLGIVGSRNELRCPECRTLVGSGVDELPSNILLVRLLDGIKQRPWKPGPGGGGSTTCTNVLRAQGSTVVNCG-SKDLQSPQCGQQPRVQAWSPPVRGIPQLPCAKALYNYEGKEPGDLKFSKGDIIILRRQVDENWYHGEVNGVHGFFPTNFVQIIKPLPQPPPQCKALYDFEVKDKEADKDCLPFAKDDVLTVIRRVDENWAEGMLADKIGIFPISYVEFNSAAKQLIEWDKPPVPGVDTAECPSATA--AQSSSASKHSDTKKNTRKRHSFTSLTMANKSSQASQ-NRHSMEISPPVLISSSNPTAAARISELSG-LSCSAPSQVHISTTGLIVTPPPSSPVTTGPSFTFPTDVPYQAALGTMNPPLPPPPLLATTVLASTPSGATAAAVAAAAAAVAAGVGPRPAVGSTEQIAHLRPQTRPSVYVAIYPYTPRKEDELELRKGEMFLVFERCQDGWYKGTSMHTSKIGVFPGNYVAPVTRAVTNASQAKVPMSTAGQASRGVTMVSPSTAGGPAQKPQGNGVAGNPS---VVPTAVVSAAHIQTSPQAKVLLHMTGQMTVNQARNAVRTVAAHNQERPTAAVTPIQVQNAACIGPASVGLPHHSLAS-QPLPPMVGPAAHIAAVNINRTSVPLACAAGASSLASPNMTTAALETEPSGRT-VTILPGLPTSPESAASACGNSSAVKPDKDSKKEKKGLLKLLSGASTKRKPRVSPPASPTLDVELGSGEVPLQGAVGPELPLG---GVHGRVGSCPTDGDGPVAAGTA--ALAQDAFHRKTSSLDSAVPIAPPPRQACSSLGPVMNEARPVVCERHRVVVSYPPQSEAELELKEGDIVFVHKKREDGWFKGTLQRNGKTGLFPGSFVENI", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q69ZI1-1", "uniprot_id": "SH3R1_MOUSE", "id": "Q69ZI1-1", "name": "E3 ubiquitin-protein ligase SH3RF1", "aln": "MDESALLDLLECPVCLERLDASAKVLPCQHTFCKRCLLGIVGSRNELRCPECRTLVGSGVDELPSNILLVRLLDGIKQRPWKPGPGGGGGTTCTNTLRAQGSTVVNCG-SKDLQSSQCGQQPRVQAWSPPVRGIPQLPCAKALYNYEGKEPGDLKFSKGDIIILRRQVDENWYHGEVSGVHGFFPTNFVQIIKPLPQPPPQCKALYDFEVKDKEADKDCLPFAKDDVLTVIRRVDENWAEGMLADKIGIFPISYVEFNSAAKQLIEWDKPPVPGVDTAECPSAT---AQSTSASKHPDTKKNTRKRHSFTSLTMANKSSQGSQ-NRHSMEISPPVLISSSNPTAAARISELSG-LSCSAPSQVHISTTGLIVTPPPSSPVTTGPAFTFPSDVPYQAALGSMNPPLPPPPLLAATVLASTPSGATAAVAAAAAAAAAAGMGPRPVMGSSEQIAHLRPQTRPSVYVAIYPYTPRKEDELELRKGEMFLVFERCQDGWYKGTSMHTSKIGVFPGNYVAPVTRAVTNASQAKVSMSTAGQASRGVTMVSPSTAGGPTQKPQGNGVAGNPS---VVPTAVVSAAHIQTSPQAKVLLHMSGQMTVNQARNAVRTVAAHSQERPTAAVTPIQVQNAACLGPASVGLPHHSLAS-QPLPPMAGPAAHGAAVSISRTNAPMACAAGAS-LASPNMTSAMLETEPSGRT-VTILPGLPTSPESAASACGNSSAGKPDKDSKKEKKGLLKLLSGASTKRKPRVSPPASPTLDVELGAGEAPLQGAVGPELPLG---GSHGRVGSCPTDGDGPVAAGTA--ALAQDAFHRKTSSLDSAVPIAPPPRQACSSLGPVMNEARPVVCERHRVVVSYPPQSEAELELKEGDIVFVHKKREDGWFKGTLQRNGKTGLFPGSFVENI", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q7Z6J0-1", "uniprot_id": "SH3R1_HUMAN", "id": "Q7Z6J0-1", "name": "E3 ubiquitin-protein ligase SH3RF1", "aln": "MDESALLDLLECPVCLERLDASAKVLPCQHTFCKRCLLGIVGSRNELRCPECRTLVGSGVEELPSNILLVRLLDGIKQRPWKPGPGGGSGTNCTNALRSQSSTVANCS-SKDLQSSQGGQQPRVQSWSPPVRGIPQLPCAKALYNYEGKEPGDLKFSKGDIIILRRQVDENWYHGEVNGIHGFFPTNFVQIIKPLPQPPPQCKALYDFEVKDKEADKDCLPFAKDDVLTVIRRVDENWAEGMLADKIGIFPISYVEFNSAAKQLIEWDKPPVPGVDAGECSSAA---AQSSTAPKHSDTKKNTKKRHSFTSLTMANKSSQASQ-NRHSMEISPPVLISSSNPTAAARISELSG-LSCSAPSQVHISTTGLIVTPPPSSPVTTGPSFTFPSDVPYQAALGTLNPPLPPPPLLAATVLASTPPGAT-------AAAAAAGMGPRPMAGSTDQIAHLRPQTRPSVYVAIYPYTPRKEDELELRKGEMFLVFERCQDGWFKGTSMHTSKIGVFPGNYVAPVTRAVTNASQAKVPMSTAGQTSRGVTMVSPSTAGGPAQKLQGNGVAGSPS---VVPAAVVSAAHIQTSPQAKVLLHMTGQMTVNQARNAVRTVAAHNQERPTAAVTPIQVQNAAGLSPASVGLSHHSLASPQPAPLMPGSATHTAAISISRASAPLACAAAAP-LTSPSITSASLEAEPSGRI-VTVLPGLPTSPDSASSACGNSSATKPDKDSKKEKKGLLKLLSGASTKRKPRVSPPASPTLEVELGSAELPLQGAVGPELPPG---GGHGRAGSCPVDGDGPVTTAVAGAALAQDAFHRKASSLDSAVPIAPPPRQACSSLGPVLNESRPVVCERHRVVVSYPPQSEAELELKEGDIVFVHKKREDGWFKGTLQRNGKTGLFPGSFVENI", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A5D8S5-1", "uniprot_id": "SH3R1_DANRE", "id": "A5D8S5-1", "name": "E3 ubiquitin-protein ligase SH3RF1", "aln": "MDESALLDLLECPVCLERLDATAKVLPCQHTFCRRCLLGIVGSRGELRCPECRTLVESGVDELPSNILLVRLLDGIKQRPRRTGSVHG---TCANGSAVAGVRAQGAGGSQRDPGPTGGQSQRVQAKSTPVRGVPQLPCAKALYNYDGKEPGDLKFSKGDIIILRRQVDENWYHGEMGGVHGFFPTNFVQVIKPLPQPPPQCKALYDFELKDKEADKDCLPFSKDDILTVIRRVDENWAEGMLGDKIGIFPISYVEFNSAARQLIELDKPSEGGGDSSEGPSSSSSGPQANGSQKAPGEKKNSKKRHSFTSLTMSHKPCLAPPPQRHSMEISGPVLISSSNPTAAARIGELSGGLSSSAPSQVHICTTGLIVTPPPSSPVTTATVFTFPPETSYASIPVDALPPPPPPPPQSQSSVVG-------------AAALNAGQRPSPAAGDQS------GRQRPTVYVAMFPYSPRKEDELELRKGEMFLVLERCQDGWFKGTSMHTGKIGVFPGNYMSPVSRTVSGSSQPKVPLTLCSQAGRGVTIVSPSSALGSMDLSKPLPVCPNATPSCSLPAAVVTAAHLPTGQHPKVLMHVTSQMTVNQARNAVRTAVSHSQDRPTAAVTPIQSHNPVAYLPS-------TAVVLQASPVLN----SSSGCSSARVGVALGCAAASL--TPPNVSAASLDTDAMRPVPMVALPVNAGSTKPLGAASNHGVACRLDKDCKREKKGLLKLLS---NKKKLRPSPPSSPTLEAEQSVSMELPQGAVGPEMALSGSAGHNGRIGACPMDSELSMSSSSS----NTDAVTHRSSPQDNTAPIAPPPRQPCSSLLSMQHDGRPIVCERYRVVVSYPPQSEAELELKEGDIVFVHKKREDGWFKGTLQRNGRTGLFPGSFVDSI", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*********************:***********:**********.*********** ***:******************* :.*. * .*:* . . ... *: .. **. ***: *.****:************:*****************************:.*:**********:******************:************:***:****************.*****************:**** ***. * *:.* .*:: .*:. : * .. ***::**********::*.. .. :******* ***************.**** **.********.****************.. ****.:..* : ** **** : : :.. *** ** * * *. . : **:****::**:*****************:*******:*******.*********::**:*:*:.:**.**.:: ..*:.****:****:* *. : : *. ..: :*:***:***: *. :.***:*::.*************..:*.*:********** :*.. *: : . *. * : :. . *....:.***.: :.*.:::* *:::. :. ** . *... .:*..:. * : ***.*:********** .*:* * ***:****:.* . . *******:. . * :** *:** *.: .:::. : **. :::*. *.:.********.**** .: ::.**:****:*****************************************:*********:.*", "identical_positions": 539, "similar_positions": 200, "identity": "59.3%" }, { "cls_id": "homologset.agr.MGI:1913096", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "M0R8J3-1", "uniprot_id": "M0R8J3_RAT", "id": "M0R8J3-1", "name": "", "aln": "MSFALEETLESDWVAVRPHVFDEREKHKFVFIVAWNEIEGKFAITCHNRTAQRQRSGSREQTGTS--------ASDGSRGPGSPAARGRPEAAASST-ALRSPGPRKSQAWTESGSPRSARSLREDS-LRGPLAKGPESPLRSPVRAKASPHRRGAESRDAT-AGATPTPPAP---PVSSVRVVSASGAVSEEIEVLELVREDEAPQPLPDSEQSPSAAEQESPAEECSWAGLFSFQDLRAVHQQLCSVNSQLEPCLPVFPEEPSGMWTVLFGGAPEMTEQEIDALCYQLQVYLGHGLDTCGWKILSQVLFTETDDPEEYYESLSELRQKGYEEVLQRARRRIQELLDKHKTIESMVELLDLYQMEDEAYSSLAEATTELYQYLLQPFRDMRELAMLRRQQIKISMENDYLGPRRIESLQKEDADWQRKAHMAVLSIQDLTVKYFEITAKAQKAVYDRMRADQKKFGKASWAAAAERMEKLQYAVSKETLQMMRAKEICLEQKKHALKEEMQSLQGGTEAIAQLDQLEADYYALQLQLYEVQFEVLKCEELLLTAQLESIRRLVSEKRDEVVYYDTYESMEAMLEKEEVAASVHAQREELQKLQQKARQLEARRGRVSAKKAYLRNKKEICIAKHHEKFQQRFQSEDEYRAHHTIQLKRDKLHEEEERKSAWVSQERQRTLDRLRTFKQRYPGQVILKSTRLRAAHSRRKST-ASPVPCEEQCDSLPAVLQGEGK-AEAGEGRGQLGSSQTAEPRSLVQLEDTSSVQLESTSLPPRAVTS-ERPPPESAPLLTNSDPERCSVTIDPLPAPLPPTPPPPPPPPPPPPPP-LPVAKDSGATTPAETLEKDALRTECGGKGIPKSASAP-TAHLFDSSQLVSARRKLRKTA--EGLQRRRVSSPMDEVLASLKRGSFHLKKVEQRTLPPFPDEDDSNNILAQIRKGVKLKKVQKEVLRESFTLLPDADPLTRSIHEALRRIKEASPESEDEDEALPGTDWEN", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9QXM1-1", "uniprot_id": "JMY_MOUSE", "id": "Q9QXM1-1", "name": "Junction-mediating and -regulatory protein", "aln": "MSFALEETLESDWVAVRPHVFDEREKHKFVFIVAWNEIEGKFAITCHNRTAQRQRSGSREQAGTP--------ASDGSRGPGSPAARGRSEAAASATAALRSPGPRKSQAWAEGGSPRSARSLKGDP-PRGPAGRGPESPLRSPARAKASPLRRSAESRDAI-ASATPVPPAPPVPPVSSVRVVSASGAVSEEIEVLEMVREDEAPQPLPDSEQPPSAAELESSAEECSWAGLFSFQDLRAVHQQLCSVNSQLEPCLPVFPEEPSGMWTVLFGGAPEMTEQEIDALCYQLQVYLGHGLDTCGWKILSQVLFTETDDPEEYYESLSELRQKGYEEVLQRARRRIQELLDKHKTIESMVELLDLYQMEDEAYSSLAEATTELYQYLLQPFRDMRELAMLRRQQIKISMENDYLGPRRIESLQKEDADWQRKAHMAVLSIQDLTVKYFEITAKAQKAVYDRMRADQKKFGKASWAAAAERMEKLQYAVSKETLQMMRAKEICLEQKKHALKEEMQSLQGGTEAIARLDQLESDYYDLQLQLYEVQFEILKCEELLLTAQLESIKRLISEKRDEVVYYDTYESMEAMLEKEEMAASVHAQREELQKLQQKARQLEARRGRVSAKKAYLRNKKEICIAKHHEKFQQRFQSEDEYRAHHTIQIKRDKLHDEEERKSAWVSQERQRTLDRLRTFKQRYPGQVILKSTRLRVAHSRRKST-ASPVPCEEQCHSLPTVLQGQEK-TEVGGGGSQLGPSQTAEPQSLVQLEDTSSEQLESTSLPPRAVVSSELPPPQSAPLLTSIDPKPCSVTIDPLPPPLPPTPPPPPPPPPPPPPP-LPVAKDNGASTTAETLEKDALRTEGNERSIPKSASAP-AAHLFDSSQLVSARKKLRKTV--EGLQRRRVSSPMDEVLASLKRGSFHLKKVEQRTLPPFPDEDDSNNILAQIRKGVKLKKVQKEVLRESFTLLPDTDPLTRSIHEALRRIKEASPESEDEEEALPCTDWEN", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8N9B5-1", "uniprot_id": "JMY_HUMAN", "id": "Q8N9B5-1", "name": "Junction-mediating and -regulatory protein", "aln": "MSFALEETLESDWVAVRPHVFDEREKHKFVFIVAWNEIEGKFAITCHNRTAQRQRSGSREQAGARGGAEAGGAASDGSRGPGSPAGRGRPEATASAT-LVRSPGPRRSSAWAEGGSPRSTRSLLGDPRLRSPGSKGAESRLRSPVRAKPIPGQKTSEADDAAGAAAAAARPAPREAQVSSVRIVSASGTVSEEIEVLEMVKEDEAPLALSDAEQPPPATELESPAEECSWAGLFSFQDLRAVHQQLCSVNSQLEPCLPVFPEEPSGMWTVLFGGAPEMTEQEIDTLCYQLQVYLGHGLDTCGWKILSQVLFTETDDPEEYYESLSELRQKGYEEVLQRARKRIQELLDKHKNTESMVELLDLYQMEDEAYSSLAEATTELYQYLLQPFRDMRELAMLRRQQIKISMENDYLGPRRIESLQKEDADWQRKAHMAVLSIQDLTVKYFEITAKAQKAVYDRMRADQKKFGKASWAAAAERMEKLQYAVSKETLQMMRAKEICLEQRKHALKEEMQSLRGGTEAIARLDQLEADYYDLQLQLYEVQFEILKCEELLLTAQLESIKRLISEKRDEVVYYDTYESMEAMLEKEEMAASAYLQREELQKLQQKARQLEARRGRVSAKKSYLRNKKEICIAKHNEKIQQRTRIEDEYRTHHTVQLKREKLHDEEERKSAWVSQERQRTLDRLRTFKQRYPGQVILKSTRLRLAHARRKGA-ASPVLQEDHCDSLPSVLQVEEKTEEVGEGRVKRGPSQTTEPQSLVQLEDTSLTQLEATSLPLSGVTS-ELPPTISLPLLNN-NLEPCSVTINPLPSPLPPTPPPPPPPPPPPPPPPLPVAKDSGP----ETLEKDLPRKEGNEKRIPKSASAP-SAHLFDSSQLVSARKKLRKTA--EGLQRRRVSSPMDEVLASLKRGSFHLKKVEQRTLPPFPDEDDSNNILAQIRKGVKLKKVQKDVLRESFTLLPDTDPLTRSIHEALRRIKEASPESEDEEEALPCTDWEN", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6NVC9-1", "uniprot_id": "JMY_DANRE", "id": "Q6NVC9-1", "name": "Junction-mediating and -regulatory protein", "aln": "MSFAMEDAIESGWVSVRPNVFEEKEKHKFVFIVAWNEIEGKFAVTCHNRTVQK-RSAERD--------------------SLLEAAEGELAAAADTD-------------------RRTAR-----------------PAHRSPGRERSGG---------------------------------QSSPSAAAELELLDAAEDAEL-----------------SARQDSSWAGLFSFQDLRAAHLQLCAVNADLEPCLPALPEEQTGVWSVLFG-VPEMSARDTDALCFQLQVYLGHALDTCGWRILSQVLFPDSEDAEEYYESLSELRQKGYEDALQRAKRRLQQLLEQQRAVERMVELLQLYSEQDEAYGELVEATTELYHYLLQPFRDMRELAMLRRQQIKISLETERLGPRRVESLRREDEDWQRKAHTAVLSIQDLTVKYFETTARAQKVMYERMRADQRKFGKAAWGAAVERMERLQYAVSKETLQLMRAKEICLEQRKHGLREEMQGLQGGEDAMARLDQLEALYYELQLQLYEIQFEILKNEELLLTAQLQSLRRQMSERQEEVVYYDTFESPDAMKATEDPAQPQTP-RDDINKLQQRTRQLEARRGRITAKKAYLKNKKEICIINHTQKLQQRQAGAHGVSQQPLLQDE----EDEEEQRLSRVSQERQRTLDRLRSFKQRYPGQVTLKSTRLRLAFSRKKALRAEQMQTQTQPQTQAASVQTDDAPAPLEP---PSAVPELCRPDSFLSLPPMGGAVAEAP--PSAELTS--LPPARELLLLDS--------------STSPMSPPPPPPPPPPPPPP---------------MLEDFPPRSPPE----PQSPLGPFSARFFDSSQLLNARKKLRKTASLESSQWRRASSPMDEVLASLKRGSFHLRKAELRVLAPDPDEDDGNNILAQIRKGVKLRKVRRQERSARAIMADSADPLTRSIHEALRRIKEASPESESEDDTPTATDWES", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "****:*:::**.**:***:**:*:*******************:******.*: **..*: . *..*. *:*.: *::* . *** * :. .:* :.: *:*:*: ..: * *. ::.*************.* ***:**::******.:*** :*:*:**** .***: :: *:**:********.******:*******.:::*.****************:.****::*:*:**:::: * *****:**. :****..*.*******:***********************:*.: *****:***::** ******* ************** **:***.:*:******:*****:*.**.****:***********:**********:**.*:****.*:** :*:*:*****: ** *******:***:** *********:*::* :**:::*******:** :** .*: * . *::::****::*********::***:**:******* :* :*:*** . : :* : .:***:: : *************:********* ******* *.:*:*. *. : : : .: .: :* : . .: .* *::.* . *:. * :.* **. . ** . .. * :************** **. *. *:*. .* :*::******:.**:*****. *. * **.******************:*.* *.*.* *****.*************:**::: : .:**********************.*::: . ****.", "identical_positions": 511, "similar_positions": 207, "identity": "51.15%" }, { "cls_id": "homologset.agr.MGI:1913099", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9D0P7-1", "uniprot_id": "PSRC1_MOUSE", "id": "Q9D0P7-1", "name": "Proline/serine-rich coiled-coil protein 1", "aln": "MEDLKEDIKFIVDETLDFGGLSPSDSHEEEDITVLVSPEKPLRRGLAHRSNPNEVAPALQGVRFSLGPLSPEKLEEILDEANRLAAQLEECALKDRERAGTGPGRPSPRGKPSPRRETFVLKDSPVRDLLPTVSSWS--TPPPSSLAG-LRSSDKKGSARAVRVASGKKPSSIKKESPTCNLFPASKSPGRSPLAQPILPPRRKTGFGARTTAS------------------------------PPIPVR--PVPQSSASNSQCSSRLQGAAVKSSSRLPVPSAIPKPATRVPLIGRSLPPGKGALAPDSLSTQKGHP--SAIGHRASVSQKTNLPTTSAARGRTTSAARGRAQPLRKAAVPGPTR", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q3KR66-1", "uniprot_id": "PSRC1_RAT", "id": "Q3KR66-1", "name": "Proline/serine-rich coiled-coil protein 1", "aln": "MEDLKEDIKFIVDETLDFGGLSPSDSHEEEDITVLVSPEKPLRRGLSHRSNPNAVAPALQGVRFSLGPLSPEKLEEILDEANRLAAQLEECALKDSENAAAGPGRPSPRGKPSPRRETFVLKDSPVRDLLPTVSSWS--APPPSNLTG-LRSSDKKGSARAGRVTAGKKPSSIKKESPTCNLFSASKNPGRSPLAQPTLPPRRKTGSGARTVAS------------------------------PPIPVR--PAPQSSASNSQCSSWLQGAAAKSSSRLPFPSAIPKPAIRMPLTGRSIPAGKGALAPDPLPTQKGHP--STVGHRAPVSQRTNLPTIGAARGRTSSAARGRVQPLRKAAVPGPTR", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q6PGN9-1", "uniprot_id": "PSRC1_HUMAN", "id": "Q6PGN9-1", "name": "Proline/serine-rich coiled-coil protein 1", "aln": "MEDLEEDVRFIVDETLDFGGLSPSDSREEEDITVLVTPEKPLRRGLSHRSDPNAVAPAPQGVRLSLGPLSPEKLEEILDEANRLAAQLEQCALQDRESAGEGLG--PRRVKPSPRRETFVLKDSPVRDLLPTVNSLTRSTPSPSSLTPRLRSNDRKGSVRALRATSGKRPSNMKRESPTCNLFPASKSPASSPLTRSTPPVRGRAGPSGRAAASEETRAAKLRVSGSGEFVGLTLKFLHPSPPGPPTPIRSVLAPQPSTSNSQRLPRPQGAAAKSSSQLPIPSAIPRPASRMPLTSRSVPPGRGALPPDSLSTRKGLPRPSTAGHRVRESG-HKVPVSQRLNLPVMGATRSNLQPPRKVAVPGPTR", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "****:**::*****************:*********:*********:***:** **** ****:*************************:***:* * *. * * . * ***********************.* : :*.**.*: ***.*:***.** *.::**:**.:*:********.***.*. ***::. * * ::* ..*:.** ** *:* .**.*:**** . ****.****:**.*****:** *:** .**:*.*:***.**.*.*:** * *: ***. * ::*. . . .*:*.. ** **.*******", "identical_positions": 216, "similar_positions": 70, "identity": "59.02%" }, { "cls_id": "homologset.agr.MGI:1913100", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O95484-1", "uniprot_id": "CLD9_HUMAN", "id": "O95484-1", "name": "Claudin-9", "aln": "MASTGLELLGMTLAVLGWLGTLVSCALPLWKVTAFIGNSIVVAQVVWEGLWMSCVVQSTGQMQCKVYDSLLALPQDLQAARALCVIALLLALLGLLVAITGAQCTTCVEDEGAKARIVLTAGVILLLAGILVLIPVCWTAHAIIQDFYNPLVAEALKRELGASLYLGWAAAALLMLGGGLLCCTCPPPQVERPRGPRLGYSIPSRSGASGLDKRDYV", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9Z0S7-1", "uniprot_id": "CLD9_MOUSE", "id": "Q9Z0S7-1", "name": "Claudin-9", "aln": "MASTGLELLGMTLAVLGWLGTLVSCALPLWKVTAFIGNSIVVAQVVWEGLWMSCVVQSTGQMQCKVYDSLLALPQDLQAARALCVVALLLALLGLLVAITGAQCTTCVEDEGAKARIVLTAGVLLLLSGILVLIPVCWTAHAIIQDFYNPLVAEALKRELGASLYLGWAAAALLMLGGGLLCCTCPPSHFERPRGPRLGYSIPSRSGASGLDKRDYV", "tax_id": 10090, "tax_name": "Mouse" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*************************************************************************************:*************************************:***:***********************************************************.:.***************************", "identical_positions": 211, "similar_positions": 6, "identity": "97.24%" }, { "cls_id": "homologset.agr.MGI:1913101", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "G3V7A9-1", "uniprot_id": "G3V7A9_RAT", "id": "G3V7A9-1", "name": "", "aln": "MSRAQISALVCGVGGFGALVAATTSNEWKVTTRASSVITATWVYQGLWMNCAAGSMASTALEIIAFVVSISGWVLVSSTLPTDYWKVSTIDGTVITTATYFANLWKMCVTDSTGVANCKDFPSMLALDGYIQACRGLMIAAVSLGFFGSIFALFGMKCTKVGGSDKAKAKIACLAGVVFILSGLCSMTGCSLYANKITTEFFDPLFMEQKYELGAALFIGWAGASLCIIG-GVIFCFSISD--NNKTPRMGYTYNGPTSVMSSRTKYQGGEGDFKTTGPSKQFDKNAYV---------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9Z0S6-1", "uniprot_id": "CLD10_MOUSE", "id": "Q9Z0S6-1", "name": "Claudin-10", "aln": "-------------------------------------------------------MASTALEIVAFVVSISGWVLVSSTLPTDYWKVSTIDGTVITTATYFANLWKICVTDSTGVANCKEFPSMLALDGYIQACRGLMIAAVSLGFFGSIFALFGMKCTKVGGSDQAKAKIACLAGIVFILSGLCSMTGCSLYANKITTEFFDPLYMEQKYELGAALFIGWAGASLCIIG-GVIFCFSISD--NNKTPRMGYTYNGPTSAMSSRTKYQGGEGDFKTTGPSKQFDKNAYV---------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P78369-1", "uniprot_id": "CLD10_HUMAN", "id": "P78369-1", "name": "Claudin-10", "aln": "-------------------------------------------------------MASTASEIIAFMVSISGWVLVSSTLPTDYWKVSTIDGTVITTATYWANLWKACVTDSTGVSNCKDFPSMLALDGYIQACRGLMIAAVSLGFFGSIFALFGMKCTKVGGSDKAKAKIACLAGIVFILSGLCSMTGCSLYANKITTEFFDPLFVEQKYELGAALFIGWAGASLCIIG-GVIFCFSISD--NNKTPR--YTYNGATSVMSSRTKYHGGE-DFKTTNPSKQFDKNAYV---------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F1QH81-1", "uniprot_id": "F1QH81_DANRE", "id": "F1QH81-1", "name": "Claudin", "aln": "-------------------------------------------------------MRNMAREILAFILCTSGWVLISSTLPTDYWKVSSIDGTVITTATFWSNLWKTCVTDSTGVSNCKDFPSMLALDGYIQVCRGLMITAVCLGFFGSIFALIGMKCTKIGGPDKFKARVVCFAGFNFACTGLCSLTAYSLYAHRITSEFFDPMFVAQKYELGAALFIGWAGSTLCLLG-GALFTLSMADGSSKKSSPNRRVASLMSGAMPQSQTSHTRRTLPEYSSTPQHFDKNAYV---------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8N7T7D3-1", "uniprot_id": "A0A8N7T7D3_DANRE", "id": "A0A8N7T7D3-1", "name": "", "aln": "---------------------------------------------------MASRTVIMYVEIACFVSCLSGWVLICSTMVTEYWIVSESAEVVLAAGDFYSNLWMDCVSDATGASDCKYFPSMMDLPAFLHISRALAVIAVIFGFWGAVLTLIGMKCTKIGGSELVNARITFAAALTYMASGLSGMTVYSWWGEKSRSEYLDPYYLDLKYELGAALFIGWGGSCLIIGGSGVMGYFSGKEAFPQSFSKQFRKPPTYLTARTRRTYMMGSRPTTVVIPPSQQSYSKRRASRVSRASRGRTETQESQSSRSVRPAWPLLDSVV", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ** .*: . *****:.**: *:** ** .*:::. :::*** **:*:**.::** ****: * .::: .*.* : ** :**:*::::*:******:**.: :*::. *.. : :**..:* * :..: :*::** :: ************.*: * : * *.: :* : :. . . . . ..:: .: . ", "identical_positions": 73, "similar_positions": 78, "identity": "22.67%" }, { "cls_id": "homologset.agr.MGI:1913102", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8M1P6R7-1", "uniprot_id": "A0A8M1P6R7_DANRE", "id": "A0A8M1P6R7-1", "name": "", "aln": "MVSAGLQMVGIALAVIGWIGVIVVCILPMWQVTAFIGQNIVTAQVTWEGIWMSCVVQSTGQMQCKVYDSMLALSSDLQAARALCIISILVGVVGILLAAAGGKCTTCIKEERAKAKVCVISGAIFIVAGVLCLIPVCWTANNIIRDFYNPMTNSAQKRELGASLFIGWGASALLIIGGSLLCANCPP--QDQYKATY-TARSGGTKGYV---", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "O14493-1", "uniprot_id": "CLD4_HUMAN", "id": "O14493-1", "name": "Claudin-4", "aln": "MASMGLQVMGIALAVLGWLAVMLCCALPMWRVTAFIGSNIVTSQTIWEGLWMNCVVQSTGQMQCKVYDSLLALPQDLQAARALVIISIIVAALGVLLSVVGGKCTNCLEDESAKAKTMIVAGVVFLLAGLMVIVPVSWTAHNIIQDFYNPLVASGQKREMGASLYVGWAASGLLLLGGGLLCCNCPPRTDKPYSAKYSAARSAAASNYV---", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9Z0S4-1", "uniprot_id": "CLD13_MOUSE", "id": "Q9Z0S4-1", "name": "Claudin-13", "aln": "MVVSKQEAISFSVTSLGWVGAIVSCVLPVWRVT-FPDDETDPDATIWEGLWHICQVRENRWIQCTLYDTRILVAQDIKVSRVFMVICTIGTWLGLLLCVLGDWRINCFMNFTIEENLLKVAGGMFLSVGLLMLVPLSWVTHNIIHGFFNPLLGFSKKVQMGSSLSLAWTSSLLLLLGGILLCVNIPVCRDFPRCIETPSARPSGANNDTLDV", "tax_id": 10090, "tax_name": "Mouse" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*. : :.:::: :**:..:: * **:*:** * ..: . . ***:* * *:.. :**.:**: : :..*::.:*.: :*. : :*:**.. *. .*: : : : ::* :*: .*:: ::*:.*.::***:.*:**: .:* ::*:** :.* :* **::** *** * * : :**...:.. . ", "identical_positions": 56, "similar_positions": 89, "identity": "26.42%" }, { "cls_id": "homologset.agr.MGI:1913103", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9Z0S5-1", "uniprot_id": "CLD15_MOUSE", "id": "Q9Z0S5-1", "name": "Claudin-15", "aln": "MSVAVETFGFFMSALGLLMLGLTLSNSYWRVSTVHGNVITTNTIFENLWYSCATDSLGVSNCWDFPSMLALSGYVQGCRALMITAILLGFLGLFLGMVGLRCTNVGNMDLSKKAKLLAIAGTLHILAGACGMVAISWYAVNITTDFFNPLYAGTKYELGPALYLGWSASLLSILGGICVFSTCCCSSKEEPATRAGLPYKPSTVVIPRATSD-ESDISFGKYGKNAYV", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D3ZQJ0-1", "uniprot_id": "CLD15_RAT", "id": "D3ZQJ0-1", "name": "Claudin-15", "aln": "MSIAVETFGFFMSALGLLMLGVTLPNSYWRVSTVHGNVITTNTIFENLWYSCATDSLGVSNCWDFPSMLALSGYVQGCRALMITAILLGFLGLFLGMVGLRCTNVGNIDLSRKAKLLAIAGAFHILAGACGMVAISWYAVNITTDFFNPLYVGTKYELGSALYLGWSASLLSILGGICVFSTCCCDSKEDPATRVGLPYKPSTVVTARATSD-ESDVSFGKYGKNAYV", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P56746-1", "uniprot_id": "CLD15_HUMAN", "id": "P56746-1", "name": "Claudin-15", "aln": "MSMAVETFGFFMATVGLLMLGVTLPNSYWRVSTVHGNVITTNTIFENLWFSCATDSLGVYNCWEFPSMLALSGYIQACRALMITAILLGFLGLLLGIAGLRCTNIGGLELSRKAKLAATAGALHILAGICGMVAISWYAFNITRDFFDPLYPGTKYELGPALYLGWSASLISILGGLCLCSACCCGSDEDPAASARRPYQAPVSVMPVATSDQEGDSSFGKYGRNAYV", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "**:*********:::******:**.************************:********* ***:**********:*.****************:**:.******:*.::**:**** * **::***** **********.*** ***:*** *******.**********:*****:*: *:***.*.*:**: . **:... * . **** *.* ******:****", "identical_positions": 174, "similar_positions": 39, "identity": "76.32%" }, { "cls_id": "homologset.agr.MGI:1913105", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q62773-1", "uniprot_id": "S28A2_RAT", "id": "Q62773-1", "name": "Sodium/nucleoside cotransporter 2", "aln": "--MAKSEGRKSASQDTSENGMENPGLELMEVGNLEQGKTLEEVTQGHSLKDGLGHSSLW-RRILQPFTKARSFYQRHAGLFKKILLGLLCLAYAAYLLAACILNFRRALALFVITCLVIFILACHFLKKFFAKKSIR-CLKPLKNTRLR----LWLKRVFMGAAVVGLILWLALDTAQRPEQLISFAGICMFILILFACSKHHSAVSWRTVFWGLGLQFVFGILVIRTEPGFNAFQWLGDQIQIFLAYTVEGSSFVFGDTLVQS-VFAFQSLPIIIFFGCVMSILYYLGLVQWVIQKIAWFLQITMGTTAAETLAVAGNIFVGMTEAPLLIRPYLADMTLSEIHAVMTGGFATIAGTVLGAFISFGIDASSLISASVMAAPCALALSKLVYPEVEESKFKSKEGVKLPRGEERNILEAASNGATDAIALVANVAANLIAFLAVLAFINSTLSWLGEMVDIHGLTFQVICSYVLRPMVFMMGVQWADCPLVAEIVGVKFFINEFVAYQQLSQYKNKRLSGVEEWINGEKQWISVKAEIIATFSLCGFANLTSIGITLGGLTSMVPQRKSDLCKLVVRALFTGACVSFISACMAGILYVPRGAETDCVSFLN-TNFTNRTYETYVCCRELFQSTLLNGTNMPSFSGPWQDKESSLRNLAKCCDLYTSTVCA", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0A8I6AFM8-1", "uniprot_id": "A0A8I6AFM8_RAT", "id": "A0A8I6AFM8-1", "name": "", "aln": "--MAKSEGRKSASQDTSENGMENPGLELMEVGNLEQGKTLEEVTQGHSLKDGLGHSSLW-RRILQPFTKARSFYQRHAGLFKKILLGLLCLAYAAYLLAACILNFRRAQALFVITCLVIFILACHFLKKFFAKKSIR-CLKPLKNTRLR----LWLKRVFMGAAVVGLILWLALDTAQRPEQLISFAGICMFLLILFACSKHHSAVSWRTVFWGLGLQFVFGILVIRTEPGFNAFQWLGDQIQIFLAYTLKGSSFVFGDTLVQS-VFAFQSLPIIIFFGCVMSILYYLGLVQGVIQKNTWLLQITMGTTAAETLAVAGNIFVGMVST---------------------------------------------LESSV----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O88627-1", "uniprot_id": "S28A2_MOUSE", "id": "O88627-1", "name": "Sodium/nucleoside cotransporter 2", "aln": "--MEKSKGRKSVSQATVENCMENPGLELMEGGNLEQRYTQEEVTQGHSLEDGLGHSSLWSRRIFQPFTKARSFFERHAGLFRKILLGLLCLAYAAYFLAACILNFQRALALFVITCLVIFILACHFLKKFFPKEQLR-CLKPLENTHLN----LWAKRVFVGLSVVGLILWLALDTAQRPEQLISFAGICMFILILFACSKHHSAVCWRTVFWGLGLQFIFGILVIRTEPGFNAFQWLGDQIQIFLAYTVEGSSFVFGDTLVQN-VFAFQSLPIIIFFGCVMSILYYLGLVQWVIQKVAWFLQITMGTTAAETLAVAGNIFVGMTEAPLLIRPYLADMTISEIHAVMTGGFATIAGTVLGAFISFGIDASSLISASVMAAPCALALSKLVYPEVEESKFKSKEGLKLPRGEERNILEAASNGATDAISLVANVAANLIAFLAVLAFINATLSWLGEMVDIHGLSFQVICSYVLRPMVFMMGVQWADCPLVAEIVGVKFFINEFVAYQQLSQYKNKRLSGVEEWINGEKQWISVKAEIITTFSLCGFANLSSIGITLGGLTSMIPQRKSDLCKIVVRALFTGACVSFISACMAGILYVPRGAETDCVSFLN-TNFTNRTYETYVCCRELFQSTSLNGTNMPSFSGPWQDNVSSLRNLASCCDLYTSTVCA", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O43868-1", "uniprot_id": "S28A2_HUMAN", "id": "O43868-1", "name": "Sodium/nucleoside cotransporter 2", "aln": "--MEKASGRQSIALSTVETGTVNPGLELMEK-EVEPEGSKRTDAQGHSLGDGLGPSTYQ-RRSRWPFSKARSFCKTHASLFKKILLGLLCLAYAAYLLAACILNFQRALALFVITCLVIFVLVHSFLKKLLGKKLTR-CLKPFENSRLR----LWTKWVFAGVSLVGLILWLALDTAQRPEQLIPFAGICMFILILFACSKHHSAVSWRTVFSGLGLQFVFGILVIRTDLGYTVFQWLGEQVQIFLNYTVAGSSFVFGDTLVKD-VFAFQALPIIIFFGCVVSILYYLGLVQWVVQKVAWFLQITMGTTATETLAVAGNIFVGMTEAPLLIRPYLGDMTLSEIHAVMTGGFATISGTVLGAFIAFGVDASSLISASVMAAPCALASSKLAYPEVEESKFKSEEGVKLPRGKERNVLEAASNGAVDAIGLATNVAANLIAFLAVLAFINAALSWLGELVDIQGLTFQVICSYLLRPMVFMMGVEWTDCPMVAEMVGIKFFINEFVAYQQLSQYKNKRLSGMEEWIEGEKQWISVRAEIITTFSLCGFANLSSIGITLGGLTSIVPHRKSDLSKVVVRALFTGACVSLISACMAGILYVPRGAEADCVSFPN-TSFTNRTYETYMCCRGLFQSTSLNGTNPPSFSGPWEDKEFSAMALTNCCGFYNNTVCA", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AC58HUD0-1", "uniprot_id": "A0AC58HUD0_DANRE", "id": "A0AC58HUD0-1", "name": "Sodium/nucleoside cotransporter", "aln": "MLEDKEDLQLTDVSYGNEQGVDNP-VFVKEDTLPDDLSDSDKESEKDSKSEKESSSCMS--KACLPITVTETFFKTHSKIIKYIVLAILAAGYLAYFIYACYLSFQRALALVVLTCLGVFILVCELVFRYKGDSIKR-CFKPVQRCFRSNM--KWMKWVFIVIVVGLLVAWLAVDTRKRPEQLISFGGVCLFIVAIFLFSAHRTAVRWSTVFWGLGLQFAIGLFVIRTEPGLVAFEWLGKQVQIFLDYTKAGSGFVFGN-LIDN-IFAFQALPIVVFFSSVMSVLYYLGVMQWVITKISWVMQVTMGTSSTETLSVAGNIFVGQTEAPLLIRPYLKDMTKSEIHAVMTGGFATIAGSVMGAFISFGIDASSLISASVMAAPCALAISKLSYPETEKSKFTSKSQIKVDSGGEQNVLEAVSGGASASIGLVANIAANLIAFLAILGFINATLRWLGGMVGYPDVTFELICSFVFMPVAFMMGIPYDESFKVAELIGTKLFLNEFIAYEKLSELKNNRLNGILD-DNGDPNWISVRSEIICTYALCGFANFSSLGIVIGGLSSICPPKKGVISSLVLRALFTGTCVSLINACIAGILFVPP---LDCVGLLQNAVFEPTTANLETCCYDLFKSTVNNGT--VSFEGSWSVVANATIYFENCCGLYNATVCM", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A1Z7N3-1", "uniprot_id": "A1Z7N3_DROME", "id": "A1Z7N3-1", "name": "", "aln": "MAEPIEGEQEEKPPPSRAKRITYLVLHVLLHIIFISYFTAATIIFIFYDKDSKECWPNRGSEATTESIDNSTEDDDDDDYDTEETSEKPVPEVKPKLLCQINWCHGYGFLIVLFILFYILWLYYWVFKPFVGIKLYNNYLEPVIDKWIAFSRQWIVSGVMLAIVLAVVVAYLGFECRNDAYKAIGLLGPVCFVLIGFAVSKHHLQVPWRIVTHGLLGQLLLGILCLRLPFGRSIFQCLGDKVTIFLNYAQHGARFVYGDRICDEYVFAFAILAVVFFFSVITSIMYYLGWMQFILNGFGFLLQAMVGTTVCESVNAAGNVFLSMTESPLVIRPYIEILTVSELHAICTSGYATVAGTVLGAYVSFGASASFLIAASVMAAPGSLAFAKLFYPETEES-LTRSDNIKLESSTDTSILDAAASGAAAALLIVLGIVSNIIAFLAIVFFLDAVTEWIFELIGLHNITLLYILSQIFIPIVFVMGVPWHDCQAIGLVVAQKSFINEFVAYRNLGILVSDKK-------------VDPRSAAIATFALCGFANPGSLGIVIASLSAMAPSRRSDITRVAFRSYFAGSFVSFTSASLAGILIQNEYTGGN-----------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : : : . : . . . :: . . :.:: : :: * .. . . ::*. . *: : :: :*..: : . : * : * *:: * * *: * * * ** *: :*:: :* * *: **.:: *** *: *: **:*: : .. :*** *.::.**. : *::**** :* :: :.:* :**: *:: .***:*:. ..: : :** ", "identical_positions": 52, "similar_positions": 87, "identity": "7.77%" }, { "cls_id": "homologset.agr.MGI:1913106", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A1W2Q6G2-1", "uniprot_id": "A0A1W2Q6G2_RAT", "id": "A0A1W2Q6G2-1", "name": "X-linked interleukin-1 receptor accessory protein-like 2", "aln": "MKLPLLLALVVCSAVSTNLKMVSKRNSVDGCIDWSVDLKTYMALAGEPVRVKCALFYSYIRTNYSMAQSTGLRLMWYRNKGDLEEPIIFSEVRMSKEEDAIWFHSAEAQDSGFYTCVLRNSTYCMKVSMSLTVAENESGLCYNSRIRYLEKSEVTKRKEISCPDMDDFKKSDQEPDVVWYKECKPKMWRSIIIQKGNALLIQEVQEEDGGNYTCELKYEGKLVRRTTELKVTALLTDKPPKPLFPMENQPSVIDVQLGKPLNIPCKAFFGFSGESGPMIYWMKGEKFIEELAGHIREGEIRLLKEHLGEKEVELTLIFDSVVEADLANYTCHVENRNGRKHASVLLRKKDLIYKIELAGGLGAIFLLLILLLVVYKCYNIELMLFYRQRFGGDETTDDNKEYDAYLSYTKVDQDTLDCDNTEEEQFALEILPDVLEKHYGYKLFIPERDLIPSGTYIEDLTRCVEQSRRLIIVLTPDYILRRGWSIFELESRLHNMLVSGEIKVILIECTELKGKVNCPEVESLKHNIKLLSLIKWKGPKSSKLNSKFWKHLVYEMPIKKKEMLSHCHVLDSAEQGLFGELQPIPSIAMTSTSATMVPSQADLPEFHHSDSMQMRHCCRGYKHEMPANTLSVPSLGNHHTYCNLPLTLLNGQLPLNNSLKETEELSRNNPLLPLSSKELSFTSDIW", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9ERS6-1", "uniprot_id": "IRPL2_MOUSE", "id": "Q9ERS6-1", "name": "X-linked interleukin-1 receptor accessory protein-like 2", "aln": "MKLPLLLALVVCSAVSTNLKMVSKRNSVDGCIDWSVDLKTYMALAGEPVRVKCALFYSYIRTNYSMAQSTGLRLMWYRNKGDLEEPIIFSEVRMSKEEDAIWFHSAEEQDSGFYTCVLRNSTYCMKVSMSLTVAENESGLCYNSRIRYLEKSEVTKRKEISCPDMDDFKKSDQEPDVVWYKECKPKMWRSIIIQKGNALLIQEVQEEDGGNYTCELKYEGKLVRRTTELKVTALLTDKPPKPLFPMENQPSVIDVQLGKPLNIPCKAFFGFSGESGPMIYWMKGEKFIEELAGHIREGEIRLLKEHLGEKEVELTLIFDSVVEADLANYTCHVENRNGRKHASVLLRKKDLIYKIELAGGLGAIFLLLILLLVVYKCYNIELMLFYRQRFGGDETTDDNKEYDAYLSYTKVDQDTLDCDNTEEEQFALEILPDVLEKHYGYKLFIPERDLIPSGTYIEDLTRCVEQSRRLIIVLTPDYILRRGWSIFELESRLHNMLVSGEIKVILIECTELKGKVNCQEVESLKHNIKLLSLIKWKGPKSSKLNSKFWKHLVYEMPIKKKEMLSHCHVLDSAEQGLFGELQPIPSIAMTSTSATMVPSQADLPEFHHSDSMQMRHCCRGYQHEMPANTLSVPSLGNHHTYCNLPLTLLNGQLPLNNSLKETEEFSRNNPLLPLTSKELSFTSDIW", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9NP60-1", "uniprot_id": "IRPL2_HUMAN", "id": "Q9NP60-1", "name": "X-linked interleukin-1 receptor accessory protein-like 2", "aln": "MKPPFLLALVVCSVVSTNLKMVSKRNSVDGCIDWSVDLKTYMALAGEPVRVKCALFYSYIRTNYSTAQSTGLRLMWYKNKGDLEEPIIFSEVRMSKEEDSIWFHSAEAQDSGFYTCVLRNSTYCMKVSMSLTVAENESGLCYNSRIRYLEKSEVTKRKEISCPDMDDFKKSDQEPDVVWYKECKPKMWRSIIIQKGNALLIQEVQEEDGGNYTCELKYEGKLVRRTTELKVTALLTDKPPKPLFPMENQPSVIDVQLGKPLNIPCKAFFGFSGESGPMIYWMKGEKFIEELAGHIREGEIRLLKEHLGEKEVELALIFDSVVEADLANYTCHVENRNGRKHASVLLRKKDLIYKIELAGGLGAIFLLLVLLVVIYKCYNIELMLFYRQHFGADETNDDNKEYDAYLSYTKVDQDTLDCDNPEEEQFALEVLPDVLEKHYGYKLFIPERDLIPSGTYMEDLTRYVEQSRRLIIVLTPDYILRRGWSIFELESRLHNMLVSGEIKVILIECTELKGKVNCQEVESLKRSIKLLSLIKWKGSKSSKLNSKFWKHLVYEMPIKKKEMLPRCHVLDSAEQGLFGELQPIPSIAMTSTSATLVSSQADLPEFHPSDSMQIRHCCRGYKHEIPATTLPVPSLGNHHTYCNLPLTLLNGQLPLNNTLKDTQEFHRNSSLLPLSSKELSFTSDIW", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AB32T1C5-1", "uniprot_id": "A0AB32T1C5_DANRE", "id": "A0AB32T1C5-1", "name": "", "aln": "MKLAGFMLFIINSAASINLKYISKRNSVDGCIDWSVDLKTYRVLAGEPLRVKCALFYSYIRTNYSVAQNAKLRLIWYRNKGDSEEPIIFSGHRLSKEGDSIWFRSAEMEDNGFYTCVLRNSTYCMKVSMSLTVEESEEGLCFSSRIRYQERAEITKSKMISCPDIDDYLAPYKQPIMTWYKECQRKEWRSSIIINTTSLWIPEVQEDDGGNYTCELKYGSKVVRRTTELKVTALLTTRPPKVLFPSERQASVIDVQLGMRLILDCKAFFGYSGDSKPIIYWMKGDKFVEELEGHIRESEVRVVREFLGEKEVELSLVFDAVEDTDMGNYTCNVENHIGRGSGSAILQKKD-MYRLELVGGLGAIMLLLGIFTAIYKCYNVEIMLCYRQHFGSDEADDGNKEYDAYLSYTKVDLDSVEQEMSEEEQFALEILPDVLEKHYGYKLFIPHRDLIPSSTYIEDLARSVEQSRRLIIVLTPEFVARRGWSIFQFEPRLHSMLVTGEIKVIMIECPDLRSVINYQEVEDLKHTIRVLTLIKWQGPKSNQLKSKFWKQVRYEMPAKKKETMSRRQVLDSGEQGLFGDLQAVSTVAMTATSASLAPTQVEIPDYNEPSHMQMRHFCRSYEYELPTT--AIATLNGRHMYCNLPMTLLNGRLTQNNIGKGKKEIHLNSSFVPLSGQELS--SDIW", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "** . :: ::: *..* *** :******************* .*****:**************** **.: ***:**:**** ******* *:*** *:***:*** :*.********************** *.*.***:.***** *::*:** * *****:**: . ::* :.*****: * *** ** : .:* * ****:*********** .*:************** :*** *** *.*.******** * : ******:**:* *:******:**:*** *****.*:*:::*.********:*:**:* ::*:.****:***: ** .*.:*:*** :*::**.******:*** :: .:*****:*:** ***:**.**: *.************** *::: : .********:****************.******.**:***:* *************::: *******::*.***.***:******:***.:*:. :* ***.**:.*::*:****:*.**.:*:*****:: **** **** :.: :****.******:**.:.::***:***::..:*.::*::: .. **:** **.*::*:*:. .:.:*..:* *****:*****:*. ** * .:*: *..::**:.:*** ****", "identical_positions": 439, "similar_positions": 173, "identity": "63.99%" }, { "cls_id": "homologset.agr.MGI:1913107", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9ERS7-1", "uniprot_id": "ILRL2_MOUSE", "id": "Q9ERS7-1", "name": "Interleukin-1 receptor-like 2", "aln": "MGVTSLLFCGVFFLLLLFVAADTCEDIFMHNVIISEGQPFPFNCTYPPETNGAVNLTWYKTPSKSPVSNNRHLRVHQDQTWILFLPLTLEDSGIYQCVIRNAHNCYQIAVNLTVLKNHWCDSSMEGSPVNSPDVYQQILPIGKSGSLNCHLYFPESCALDSIKWYKGCEEIKAGKKYSPSGAKLLVNNVAVEDGGSYACSARLTHLGRHFTIRNYIAVNTKEVE-YGRRIPNITYPKNNSIEVPLGSTLIVNCNITDTKENTNLRCWRVNNTLVDDYYKDSKRIQEGIETNVSLRDQIRYTVNITFLKVKMEDYGRPFTCHAGVSAAYIILIYPVPDFRAYLLGGLMAFLLLVVSVLFIYNSFKIDIMLWYRSAFHTAQAPDDEKLYDAYVLYPKYPRGSQGHDVDTLVLKILPEVLEKQCGYKLFIFGRDEFPGQAVASVIDENIKLCRRLMVFVAPESSSFGFLKNLSEEQIAVYNALIQHGMKVILIELEKVKDYSTMPESIQYIRQKHGAIQWDGDFTEQSQCAKTKFWKKVRYHMPPRRYPASSPVQLLGHIPCNCKAGKCNAATGLITP----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q62929-1", "uniprot_id": "ILRL2_RAT", "id": "Q62929-1", "name": "Interleukin-1 receptor-like 2", "aln": "MGMPPLLFCWVSFVLPLFVAAGNCTDVYMHHEMISEGQPFPFNCTYPPVTNGAVNLTWHRTPSKSPISINRHVRIHQDQSWILFLPLALEDSGIYQCVIKDAHSCYRIAINLTVFRKHWCDSSNEESSINSSDEYQQWLPIGKSGSLTCHLYFPESCVLDSIKWYKGCEEIKVSKKFCPTGTKLLVNNIDVEDSGSYACSARLTHLGRIFTVRNYIAVNTKEVG-SGGRIPNITYPKNNSIEVQLGSTLIVDCNITDTKENTNLRCWRVNNTLVDDYYNDFKRIQEGIETNLSLRNHILYTVNITFLEVKMEDYGHPFTCHAAVSAAYIILKRPAPDFRAYLIGGLMAFLLLAVSILYIYNTFKVDIVLWYRSTFHTAQAPDDEKLYDAYVLYPKYPRESQGHDVDTLVLKILPEVLEKQCGYKLFIFGRDEFPGQAVASVIDENIKLCRRLMVLVAPETSSFSFLKNLTEEQIAVYNALVQDGMKVILIELERVKDYSTMPESIQYIRQKHGAIQWDGDFTEQAQCAKTKFWKKVRYHMPPRRYPASPPVQLLGHTPR--IPG---------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9HB29-1", "uniprot_id": "ILRL2_HUMAN", "id": "Q9HB29-1", "name": "Interleukin-1 receptor-like 2", "aln": "--MWSLLLCGLSIALPLSVTADGCKDIFMKNEILSASQPFAFNCTFPPITSGEVSVTWYKNSSKIPVSKIIQSRIHQDETWILFLPMEWGDSGVYQCVIKGRDSCHRIHVNLTVFEKHWCDTSIGG-LPNLSDEYKQILHLGKDDSLTCHLHFPKSCVLGPIKWYKDCNEIK-GERFTVLETRLLVSNVSAEDRGNYACQAILTHSGKQYEVLNGITVSITERAGYGGSVPKIIYPKNHSIEVQLGTTLIVDCNVTDTKDNTNLRCWRVNNTLVDDYYDESKRIREGVETHVSFREHNLYTVNITFLEVKMEDYGLPFMCHAGVSTAYIILQLPAPDFRAYLIGGLIALVAVAVSVVYIYNIFKIDIVLWYRSAFHSTETIVDGKLYDAYVLYPKPHKESQRHAVDALVLNILPEVLERQCGYKLFIFGRDEFPGQAVANVIDENVKLCRRLIVIVVPESLGFGLLKNLSEEQIAVYSALIQDGMKVILIELEKIEDYTVMPESIQYIKQKHGAIRWHGDFTEQSQCMKTKFWKTVRYHMPPRRCRPFPPVQLLQHTPCYRTAGPELGSRRKKCTLTTG", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : .**:* : : * * *:*. * *::*:: ::* .***.****:** *.* *.:**::..** *:* : *:***::******: ***:*****:. ..*::* :****:.:****:* * .* *:* * :**..**.***:**:**.*..*****.*:*** .::: ::***.*: .** *.***.* *** *: : : * *:*. .* * :*:* ****:**** **:****:**:****:******************.: ***:**:**::*:*:: ********:******* ** ***.**:***** *.*******:***:*:: :.**:::*** **:**:*****:**:::: * *********** : ** * **:***:*******:********************.*****:******:*:*.**: .*.:****:*******.**:*.**********:::**:.********:******:*.******:** ******.********* . .***** * * .* ", "identical_positions": 343, "similar_positions": 137, "identity": "59.24%" }, { "cls_id": "homologset.agr.MGI:1913122", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q60774-1", "uniprot_id": "TM45A_MOUSE", "id": "Q60774-1", "name": "Transmembrane protein 45A", "aln": "MGSFKGHALPGSFFFAMGFWWTMKNILKSVYKRQTRTCYLNSKTLLRRTEIWEGVVVLLMSLTGIAGEQFISGGPALILH--KDGQWNQILGWHHTTMYLFFGLQGITQIICFTTNVLPLSSSKLMLSIAIFVETFMFYNHTHGREMIDIFVHQLLVFVGTFSGLVAFLEFLVKNNALLELLRCSLLMFQGTWFWQMAFVLYPPCGSATWNLSDIQNKMFLSMCFCWHYASILILIGVKYALANWLVKSRLRKGCTSEVGLLKHADREQESEEEV", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D4AAI6-1", "uniprot_id": "D4AAI6_RAT", "id": "D4AAI6-1", "name": "", "aln": "MGSFIGHALPGTFFIMMGFWWTTKNILKSVYKKHTRTCYLNSKTLLRRIEIWEGVVVVIMALTGIAGEQFISGGPALILY--KDGQWNQILGWHHTTMYFFFGLQGVTQIVCFTTNALPLSLSKLMLANAIFVETFIFYNHTHGREMVDIFVHQLLSYTTTAAGLVAFMEFLTKNNVLLELVRSSLILLQGTWFWQVAFVLYPPKGRATWNLSDIGNKMFLSMCFCWHYASIVMLIGVIFALANWLVKSRLRKVCTSEVGLLKHVDREQESEEEV", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9NWC5-1", "uniprot_id": "TM45A_HUMAN", "id": "Q9NWC5-1", "name": "Transmembrane protein 45A", "aln": "MGNFRGHALPGTFFFIIGLWWCTKSILKYICKKQKRTCYLGSKTLFYRLEILEGITIVGMALTGMAGEQFIPGGPHLMLYDYKQGHWNQLLGWHHFTMYFFFGLLGVADILCFTISSLPVSLTKLMLSNALFVEAFIFYNHTHGREMLDIFVHQLLVLVVFLTGLVAFLEFLVRNNVLLELLRSSLILLQGSWFFQIGFVLYPPSGGPAWDLMDHENILFLTICFCWHYAVTIVIVGMNYAFITWLVKSRLKRLCSSEVGLLKNAEREQESEEEM", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "**.* ******:**: :*:** *.*** : *::.*****.****: * ** **:.:: *:***:******.*** *:*: *:*:***:***** ***:**** *:::*:*** . **:* :****: *:***:*:**********:******** . :*****:***.:**.****:*.**:::**:**:*:.****** * .:*:* * * :**::******* ::::*: :*: .*******:: *:*******:.:********:", "identical_positions": 167, "similar_positions": 73, "identity": "60.73%" }, { "cls_id": "homologset.agr.MGI:1913125", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O88907-1", "uniprot_id": "PIAS1_MOUSE", "id": "O88907-1", "name": "E3 SUMO-protein ligase PIAS1", "aln": "--------------------------------------MADSAELKQMVMSLRVSELQVLLGYAGRNKHGRKHELLTKALHLLKAGCSPAVQMKIKELYRRRFPQKIMTPADLSIPNVHSSPMPPTLSPSTIPQLTYDGHPAS-SPLLPVSLLGPKHELELPHLTSALHPVHPDIKLQKLPFYD--------LLDELIKPTSLASDNSQRFRETCFAFALTPQQVQQISSSMDISG-TKCDFTVQVQLRFCLSETSCPQEDHFPPNLCVKVNTKPCSLPGYLPPTKNGVEPKRPSRPINITSLVRLSTTVPNTIVVSWTAEIGRTYSMAVYLVKQLSSTVLLQRLRAKGIRNPDHSRALIKEKLTADPDSEIATTSLRVSLLCPLGKMRLTIPCRALTCSHLQCFDATLYIQMNEKKPTWVCPVCDKKAPYEHLIIDGLFMEILKY---CTDCDEIQFKEDGSWAPMRS------------------------------------------------------KKEVQEVTASYNGVDG-CLSSTLEHQVASHNQSSNKN-KKVEVIDLTIDSSSDEEE-EEPPAKRTCPSLSPTS-----------------PLSNKGILSLPHQASPVSRTPSLPAVDTSYIN----------------------------TSLIQDYRHPFHMTPMPYDLQGLDFFPFLSGDN-QHYNTSLLAAAAAAVSDDQDL-----------------------------------------------------------------------------------------LHSSRFFPYTSSQMFLDQLSAGGSTSLPATNGSSSG-----------------SNSSLVSSNSLRESHGHGVASRSSAD---TASIFGIIPDIISLD---------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8I6AIY4-1", "uniprot_id": "A0A8I6AIY4_RAT", "id": "A0A8I6AIY4-1", "name": "", "aln": "--------------------------------------MADSAELKQMVMSLRVSELQVLLGYAGRNKHGRKHELLTKALHLLKAGCSPAVQMKIKELYRRRFPQKIMTPADLSIPNVHSSPMPATLSPSTIPQLTYDGHPAS-SPLLPVSLLGPKHELELPHLTSALHPVHPDIKLQKLPFYD--------LLDELIKPTSLASDNSQRFRETCFAFALTPQQVQQISSSMDISG-TKCDFTVQVQLRFCLSETSCPQEDHFPPNLCVKVNTKPCSLPGYLPPTKNGVEPKRPSRPINITSLVRLSTTVPNTIVVSWTAEIGRTYSMAVYLVKQLSSTVLLQRLRAKGIRNPDHSRALIKEKLTADPDSEIATTSLRVSLLCPLGKMRLTIPCRALTCSHLQCFDATLYIQMNEKKPTWVCPVCDKKAPYEHLIIDGLFMEILKY---CTDCDEIQFKEDGSWAPMRS------------------------------------------------------KKEVQEVTASYNGVDG-CLSSTLEHQVASHNQSSNKN-KKVEVIDLTIDSSSDEEE-EEPPAKRTCPSLSPTS-----------------PLSNKGILSLPHQASPVSRTPSLPAVDTSYIN----------------------------TSLIQDYRHPFHMTPMPYDLQGLDFFPFLSGDN-QHYNTSLLAAAAAAVSDDQDL-----------------------------------------------------------------------------------------LHSSRFFPYTSSQMFLDQLSAGGSTSLPATNGSSSG-----------------SNSSLVSSNSLRESHGHGVASRSSAD---TASIFGIIPDIISLD---------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O75925-1", "uniprot_id": "PIAS1_HUMAN", "id": "O75925-1", "name": "E3 SUMO-protein ligase PIAS1", "aln": "--------------------------------------MADSAELKQMVMSLRVSELQVLLGYAGRNKHGRKHELLTKALHLLKAGCSPAVQMKIKELYRRRFPQKIMTPADLSIPNVHSSPMPATLSPSTIPQLTYDGHPAS-SPLLPVSLLGPKHELELPHLTSALHPVHPDIKLQKLPFYD--------LLDELIKPTSLASDNSQRFRETCFAFALTPQQVQQISSSMDISG-TKCDFTVQVQLRFCLSETSCPQEDHFPPNLCVKVNTKPCSLPGYLPPTKNGVEPKRPSRPINITSLVRLSTTVPNTIVVSWTAEIGRNYSMAVYLVKQLSSTVLLQRLRAKGIRNPDHSRALIKEKLTADPDSEIATTSLRVSLLCPLGKMRLTIPCRALTCSHLQCFDATLYIQMNEKKPTWVCPVCDKKAPYEHLIIDGLFMEILKY---CTDCDEIQFKEDGTWAPMRS------------------------------------------------------KKEVQEVSASYNGVDG-CLSSTLEHQVASHHQSSNKN-KKVEVIDLTIDSSSDEEE-EEPSAKRTCPSLSPTS-----------------PLNNKGILSLPHQASPVSRTPSLPAVDTSYIN----------------------------TSLIQDYRHPFHMTPMPYDLQGLDFFPFLSGDN-QHYNTSLLAAAAAAVSDDQDL-----------------------------------------------------------------------------------------LHSSRFFPYTSSQMFLDQLSAGGSTSLPTTNGSSSG-----------------SNSSLVSSNSLRESHSHTVTNRSSTD---TASIFGIIPDIISLD---------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0ACD6B7P1-1", "uniprot_id": "A0ACD6B7P1_DANRE", "id": "A0ACD6B7P1-1", "name": "", "aln": "--------------------------------------MAESAELKQMVMSLRVSELQVLLGYAGRNKHGRKHELLTKALHLLKAGCSPAVQMKIKELYRRRFPTKLVSPAELALPGVH----PAASLPPGLTQLGFDGHGAPPSPLLPISLLGPKHELGLPHLPTNLHPVHPDVKLQRLPFYD--------LLDELIKPTSLASDNSQRFQETCFAFALTPQQVQQVSSSMDISG-TKCDFTVQVQLRFCLSETSCPQEDHFPPNLCVKVNGKPCNLPGYLPPTKNGVEPKRPSRPINITSLIRLSTTVPNTIVVSWTSEIGRSYSLAVYLVKQLSSTMLLQRLRGKGIRNPDHSRALIKEKLTADPDSEIATTSLRVSLLCPLGKMRLMIPCRALTCSHLQCFDATLYIQMNEKKPTWVCPVCDKKAPYEHLIIDGLFMEILNS---CLDCDEIQFKEDGSWAPMRS------------------------------------------------------KKEVQEVSASYNGIDGGCRTSVLEQNSQTNGSSGGGNRKKVEVIDLTLDSSSEEEEDEEPLPKKSCPSLSSLS-----------------PQMDNGVLNLHRQASPVSRTPSMPQVDTSYIPP--------------------------PPPLIQDYRH-YYSTPT--ELSDLNFFPFLQGENHQHYN--MVMAAAASASEDHDL-----------------------------------------------------------------------------------------LLS-RFLPYGSSQLFLDPPSTPVNSSLPPINVNGGS-----------------TGNSLVSSSSLRESLGHPPGPRPTSDSTPTSAIYGSIPDVISLD---------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A1Z7P5-1", "uniprot_id": "A1Z7P5_DROME", "id": "A1Z7P5-1", "name": "", "aln": "MRKTRSQTARTQAENAATSSSPGHQSTSSAPIAVNPFDSTKYKECEQMVQMLRVVELQKILSFLNISFAGRKTDLQSRILSFLRT-NLELLAPKVQEVYAQSVQEQNATLQYIDPTRMYSHIQLPPTVQPNPVGLVGSGQGVQ-VPGGQMNVVGGAPFLHTHSINSQL-PIHPDVRLKKLAFYD--------VLGTLIKPSTLVPRNTQRVQEVPFYFTLTPQQATEIASNRDIRNSSKVEHAIQVQLRFCLVETSCDQEDCFPPNVNVKVNNKLCQLPNVIPTNRPNVEPKRPPRPVNVTSNVKLSPTVTNTITVQWCPDYTRSYCLAVYLVKKLTSTQLLQRMKTKGVKPADYTRGLIKEKLTEDADCEIATTMLKVSLNCPLGKMKMLLPCRASTCSHLQCFDASLYLQMNERKPTWNCPVCDKPAIYDNLVIDGYFQEVLGSSLLKSDDTEIQLHQDGSWSTPGL------------------------------------------------------RSETQILDTPS------------------------KPAQKVEVISDDIELISDDAK----------PVKRDLS-----------------PAQDE---------QPTS-TSNSETVDLTLSD--------------------------------SDDDMPLAKRRPPAKQAVASSTSNGSGGG-QRAYTPAQQPQQSESPEQQAS-----------------------------------------------------------------------------------------RQSPEKQTVSEQQLQQQQHEQPATAAVHASLLESLA-----------------AAVADQKHFQLLDLAAVAAAAAATAS---SGQSQNAGP---------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q12216-1", "uniprot_id": "SIZ2_YEAST", "id": "Q12216-1", "name": "E3 SUMO-protein ligase SIZ2", "aln": "------MASVMSNNNNNNNNNNASYMFTNPLSNTGGGLINEIKDAINEMEQLKVLELKQICKSLDLSITGKKAVLQDRIKQFLRKSCDIGHIDPWRPKAIKILIAKVRINSSLPKYSTLWETLKTG------------------------AFKHPVASGQLPVTALQSTALPPYSQQQALAYS---------FTSPFYKPIVQIPDANKKLKQSAGRGCTKMKFKVSKSNHDLLKS-NKSYKLYLFSGFSIPFIYETVGHEAIDFPYPCELVFNGTKLEDNVKGLK---KQNGTGNPANLTPYLKVPTEMNH--LDLHYLNIDKEYSISCFIVEVFSPEALLGKILKRPKIIKQATTAYIKRTLNEQDDDDIITTSTVLSLQCPISCTRMKYPAKTDQCKHIQCFDALWFLHSQSQVPTWQCPICQHPIKFDQLKISEFVDNIIQN--CNEDVEQVEISVDGSWKPIHN--------------------------------------------------SSAVITDTVNQNHSVKNENQGTVKQEQDYDSRNAFDTNLRNGSNHNEPEIISLDSSDDEA-FIPASKS-FPTHVNPR----------NDQLRADIFPSESEGSSDYNPNHTSTPKGSPTMDQDNY----------------------QDAFQMRSFLNQGATTNINDTPTNNSS--INSFVTATNGDSRIFYNRGPSTPLLPAVLQNLTNQTEAQ--------RNPYGPNYNTTAQDRNLLG---------------------------------------------------IEGDLPPIPPVDPNSEAETELPTRTTSAAHLPPYIHVSTSG--------HGDDGKIRKRRHSNVSIYIPKNPYATLMKRRPQANHAIMNKTLAQTNDFN---TSAQDNSEVVDLTSD", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "Q04195-1", "uniprot_id": "SIZ1_YEAST", "id": "Q04195-1", "name": "E3 SUMO-protein ligase SIZ1", "aln": "----------MINLEDYWEDETP-----GPDREPTNELRNEVEETITLMELLKVSELKDICRSVSFPVSGRKAVLQDLIRNFLQNALVVGKSDPYRVQAVKFLIERIRKNEPLPVYKDLWNALRKGTPLSAITVRSMEGPPTVQQQSPSVIRQSPTQRRKTSTTSSTSRAPPPTNPDASSSSSSFAVPTIHFKESPFYKIQRLIPELVMNVEVTGGRGMCSAKFKLSKADYNLLSNPNSKHRLYLFSGMINPLGSR--GNEPIQFPFPNELRCNNVQIKDNIRGFK---SKPGTAKPADLTPHLKPYTQQNN--VELIYAFTTKEYKLFGYIVEMITPEQLLEKVLQHPKIIKQATLLYLKKTLREDEEMGLTTTSTIMSLQCPISYTRMKYPSKSINCKHLQCFDALWFLHSQLQIPTWQCPVCQIDIALENLAISEFVDDILQN--CQKNVEQVELTSDGKWTAILEDDDDSDSDSNDGSRSPEKGTSVSDHHCSSSHPSEPIIINLDSDDDEPNGNNPHVTNNHDDSNRHSNDNNNNSIKNNDSHNKNNNNNNNNNNNNNDNNNSIENNDSNSNNK-HDHGSRSNTPSHNHTKNLMNDNDDDDDDRLMAEITSNHLKSTNTDILTEKGSSAPSRTLDPKSYNIVASETTTPVTNRVIPEYLGNSSSYIGKQLPNILGKTPLNVTAVDNSSHLISPDVSVSSPTPRNTASNASSSALSTPPLIRMSSLDPRGSTVPDKTIRPPINSNSYTASISDSFVQPQESSVFPPREQNMDMSFPSTVNSRFNDPRLNTTRFPDSTLRGATILSNNGLDQRNNSLPTTEAITRNDVGRQNSTPVLPTLPQNVPIRTNSNKSGLPLINNENSVPNPPNTATIPLQKSRLIVNPFIPRRPYSNVLPQKRQLSNTSSTSPIMGTWKTQDYGKKYNSG", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . : : *:* **: : . *:* * :*: : : . : : . * . . : * . ... . : . :. : . .. .. .: : :: : .: . : : . . .* ::*. :: . : : * : ::*: ::. ** :: : : : :*..* : : : ** :** **:. :: *.:: *.*:***** ::: : : *** **:*: ::* *. . ::: : :::: **.* . .: .: : . ..: * .. . . :* . . . : . . . : . : . :. ", "identical_positions": 45, "similar_positions": 132, "identity": "4.84%" }, { "cls_id": "homologset.agr.MGI:1913126", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O70260-1", "uniprot_id": "PIAS3_RAT", "id": "O70260-1", "name": "E3 SUMO-protein ligase PIAS3", "aln": "--------------------------------------MAELGELKHMVMSFRVSELQVLLGFAGRNKSGRKHELLAKALHLLKSSCAPS-VQMKIKELYRRRFPR--KTLGPSDLSLLSLPPGTSPVGS---------PSPLASIPP--TLLTPG---TLLGPKREVDMHPP-LPQPVHPDVTMKPLPFYEVYGELIRPTTLASTSSQRFEEAHFTFALTPQQLQQILTSREVLPGAKCDYTIQVQLRFCLCETSCPQEDYFPPNLFVKVNGKLCPLPGYLPPTKNGAEPKRPSRPINITPLARLSATVPNTIVVNWSSEFGRNYSLSVYLVRQLTAGTLLQKLRAKGIRNPDHSRALIKEKLTADPDSEVATTSLRVSLMCPLGKMRLTVPCRALTCAHLQSFDAALYLQMNEKKPTWTCPVCDKKAPYESLIIDGLFMEILNS---CSDCDEIQFMEDGSWCPMKPKKE-----------------------------------------------ASEVCPPPGYGLDGLQYSPVQEGNQSENKKRVEVIDLTIESSSDEEDLPPTKKHCPVTSAAIPALPGSKGALTSGHQ--------PSSVLRSPAMGTLGSDFLSSLPLHEYPPAFPLGADIQGL----------------------------DLFSFLQTESQHYSPSVITSLDEQDTLGHFFQFRGTPPHFLGPLAPTLGSSHRSATPAPAPG--------------------------------------------------------------------------------RVSSIVAPGSSLREGHGGPLPSGPSLTGCRSDVISLD------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O54714-1", "uniprot_id": "PIAS3_MOUSE", "id": "O54714-1", "name": "E3 SUMO-protein ligase PIAS3", "aln": "--------------------------------------MAELGELKHMVMSFRVSELQVLLGFAGRNKSGRKHELLAKALHLLKSSCAPS-VQMKIKELYRRRFPR--KTLGPSDLSLLSLPPGTSPVGS---------PGPLAPIPP--TLLTPG---TLLGPKREVDMHPP-LPQPVHPDVTMKPLPFYEVYGELIRPTTLASTSSQRFEEAHFTFALTPQQLQQILTSREVLPGAKCDYTIQVQLRFCLCETSCPQEDYFPPNLFVKVNGKLCPLPGYLPPTKNGAEPKRPSRPINITPLARLSATVPNTIVVNWSSEFGRNYSLSVYLVRQLTAGTLLQKLRAKGIRNPDHSRALIKEKLTADPDSEVATTSLRVSLMCPLGKMRLTVPCRALTCAHLQSFDAALYLQMNEKKPTWTCPVCDKKAPYESLIIDGLFMEILNS---CSDCDEIQFMEDGSWCPMKPKKE-----------------------------------------------ASEVCPPPGYGLDGLQYSAVQEGIQPESKKRVEVIDLTIESSSDEEDLPPTKKHCPVTSAAIPALPGSKGALTSGHQ--------PSSVLRSPAMGTLGSDFLSSLPLHEYPPAFPLGADIQGL----------------------------DLFSFLQTESQHYGPSVITSLDEQDTLGHFFQYRGTPSHFLGPLAPTLGSSHRSSTPAPPPG--------------------------------------------------------------------------------RVSSIVAPGSSLREGHGGPLPSGPSLTGCRSDVISLD------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9Y6X2-1", "uniprot_id": "PIAS3_HUMAN", "id": "Q9Y6X2-1", "name": "E3 SUMO-protein ligase PIAS3", "aln": "--------------------------------------MAELGELKHMVMSFRVSELQVLLGFAGRNKSGRKHELLAKALHLLKSSCAPS-VQMKIKELYRRRFPR--KTLGPSDLSLLSLPPGTSPVGS---------PGPLAPIPP--TLLAPG---TLLGPKREVDMHPP-LPQPVHPDVTMKPLPFYEVYGELIRPTTLASTSSQRFEEAHFTFALTPQQVQQILTSREVLPGAKCDYTIQVQLRFCLCETSCPQEDYFPPNLFVKVNGKLCPLPGYLPPTKNGAEPKRPSRPINITPLARLSATVPNTIVVNWSSEFGRNYSLSVYLVRQLTAGTLLQKLRAKGIRNPDHSRALIKEKLTADPDSEVATTSLRVSLMCPLGKMRLTVPCRALTCAHLQSFDAALYLQMNEKKPTWTCPVCDKKAPYESLIIDGLFMEILSS---CSDCDEIQFMEDGSWCPMKPKKE-----------------------------------------------ASEVCPPPGYGLDGLQYSPVQGGDPSENKKKVEVIDLTIESSSDEEDLPPTKKHCSVTSAAIPALPGSKGVLTSGHQ--------PSSVLRSPAMGTLGGDFLSSLPLHEYPPAFPLGADIQGL----------------------------DLFSFLQTESQHYGPSVITSLDEQDALGHFFQYRGTPSHFLGPLAPTLGSSHCSATPAPPPG--------------------------------------------------------------------------------RVSSIVAPGGALREGHGGPLPSGPSLTGCRSDIISLD------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A1Z7P5-1", "uniprot_id": "A1Z7P5_DROME", "id": "A1Z7P5-1", "name": "", "aln": "MRKTRSQTARTQAENAATSSSPGHQSTSSAPIAVNPFDSTKYKECEQMVQMLRVVELQKILSFLNISFAGRKTDLQSRILSFLR-TNLEL-LAPKVQEVYAQSVQEQNATLQYIDPTRMYSHIQLPPTVQ---------PNPVGLVGSGQGVQVPGGQMNVVGGAPFLHTHSINSQLPIHPDVRLKKLAFYDVLGTLIKPSTLVPRNTQRVQEVPFYFTLTPQQATEIASNRDIRNSSKVEHAIQVQLRFCLVETSCDQEDCFPPNVNVKVNNKLCQLPNVIPTNRPNVEPKRPPRPVNVTSNVKLSPTVTNTITVQWCPDYTRSYCLAVYLVKKLTSTQLLQRMKTKGVKPADYTRGLIKEKLTEDADCEIATTMLKVSLNCPLGKMKMLLPCRASTCSHLQCFDASLYLQMNERKPTWNCPVCDKPAIYDNLVIDGYFQEVLGSSLLKSDDTEIQLHQDGSWSTPGLRSE-----------------------------------------------TQILDTP------------------SKPAQKVEVISDDIELIS--DDAKPVKRDLSPAQDEQPTSTSNSETVDLTLS--------DSDDDMPLAK--------RRPPAKQAVASSTSNGSGGGQ----------------------------RAYTPAQQPQQSESPEQQASRQSPEKQ-TVSEQQLQQQQHEQPATAAVHASLLESLAAAVAD--------------------------------------------------------------------------------QKHFQLLDLAAVAAAAAATASSGQSQNAGP-------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q12216-1", "uniprot_id": "SIZ2_YEAST", "id": "Q12216-1", "name": "E3 SUMO-protein ligase SIZ2", "aln": "-----MASVMSNNNNNNNNNNASYMFTNPLSNTGG-GLINEIKDAINEMEQLKVLELKQICKSLDLSITGKKAVLQDRIKQFLRKSCDIGHIDPWRPKAIKILIAKVRINSSLPKYSTLWETLKTG------------------------AFKHPVASGQLPVTALQSTALPPYSQQQALAYS---------FTSPFYKPIVQIPDANKKLKQSAG-RGCTKMKFKVSKSNHDLLKS-NKSYKLYLFSGFSIPFIYETV--GHEAIDFPYPCELVFNGTKLEDNVKGLKKQNGTGNPANLTPYLKVPTEMNH--LDLHYLNIDKEYSISCFIVEVFSPEALLGKILKRPKIIKQATTAYIKRTLNEQDDDDIITTSTVLSLQCPISCTRMKYPAKTDQCKHIQCFDALWFLHSQSQVPTWQCPICQHPIKFDQLKISEFVDNIIQN--CNEDVEQVEISVDGSWKPIHN--------------------------------------------------SSAVITDTVNQNHSVKNENQGTVKQEQDYDSRNAFDTNLRNGSNHNEPEIISLDSSDDEAFIPASKS-FPTHVNPR----------NDQLRADIFPSESEGSSDYNPNHTSTPKGSPTMDQDNY----------------------QDAFQMRSFLNQGATTNINDTPTNNSS--INSFVTATNGDSRIFYNRGPSTPLLPAVLQNLTNQTEAQ--------RNPYGPNYNTTAQDRNLLG---------------------------------------------------IEGDLPPIPPVDPNSEAETELPTRTTSAAHLPPYIHVSTSG--------HGDDGKIRKRRHSNVSIYIPKNPYATLMKRRPQANHAIMNKTLAQTNDFN---TSAQDNSEVVDLTSD", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "Q04195-1", "uniprot_id": "SIZ1_YEAST", "id": "Q04195-1", "name": "E3 SUMO-protein ligase SIZ1", "aln": "---------MINLEDYWEDETP-----GPDREPTN-ELRNEVEETITLMELLKVSELKDICRSVSFPVSGRKAVLQDLIRNFLQNALVVGKSDPYRVQAVKFLIERIRKNEPLPVYKDLWNALRKGTPLSAITVRSMEGPPTVQQQSPSVIRQSPTQRRKTSTTSSTSRAPPPTNPDASSSSSSFAVPTIHFKESPFYKIQRLIPELVMNVEVTGG-RGMCSAKFKLSKADYNLLSNPNSKHRLYLFSGMINPLGSR----GNEPIQFPFPNELRCNNVQIKDNIRGFKSKPGTAKPADLTPHLKPYTQQNN--VELIYAFTTKEYKLFGYIVEMITPEQLLEKVLQHPKIIKQATLLYLKKTLREDEEMGLTTTSTIMSLQCPISYTRMKYPSKSINCKHLQCFDALWFLHSQLQIPTWQCPVCQIDIALENLAISEFVDDILQN--CQKNVEQVELTSDGKWTAILEDDDDSDSDSNDGSRSPEKGTSVSDHHCSSSHPSEPIIINLDSDDDEPNGNNPHVTNNHDDSNRHSNDNNNNSIKNNDSHNKNNNNNNNNNNNNNDNNNSIENNDSNSNNKHDHGSRSNTPSHNHTKNLMNDNDDDDDDRLMAEITSNHLKSTNTDILTEKGSSAPSRTLDPKSYNIVASETTTPVTNRVIPEYLGNSSSYIGKQLPNILGKTPLNVTAVDNSSHLISPDVSVSSPTPRNTASNASSSALSTPPLIRMSSLDPRGSTVPDKTIRPPINSNSYTASISDSFVQPQESSVFPPREQNMDMSFPSTVNSRFNDPRLNTTRFPDSTLRGATILSNNGLDQRNNSLPTTEAITRNDVGRQNSTPVLPTLPQNVPIRTNSNKSGLPLINNENSVPNPPNTATIPLQKSRLIVNPFIPRRPYSNVLPQKRQLSNTSSTSPIMGTWKTQDYGKKYNSG", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : : ::* **: : . :*:* * :*: : : . . . . : * . . . : : . ..: : :. :: . : .: : : : . : . . .* ::*. : . : :.* : ::*. ::. ** :: : : : :*..* : : : ** :** **:. :: *.:: * *:*.*** :*: : : *** **:*: :.* *. . ::: . .: :::: **.* . : . . : . . . :: . . . . .. . . . . . . . * . . . :. . : . ", "identical_positions": 42, "similar_positions": 133, "identity": "4.53%" }, { "cls_id": "homologset.agr.MGI:1913128", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O35153-1", "uniprot_id": "BET1L_MOUSE", "id": "O35153-1", "name": "BET1-like protein", "aln": "----------------MAD-WTRAQSSGAVED--------------------ILDRENKRMADSLASKVTRLKSLALDIDRDTEDQNRYLDGMDSDFTSVTGLLTGSVKRFSTMARSGRDNRKLLCGMAVVLIVAFFILSYLLSRTRT", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O35152-1", "uniprot_id": "BET1L_RAT", "id": "O35152-1", "name": "BET1-like protein", "aln": "----------------MAD-WTRAQSSGAVEE--------------------IVDRENKRMADSLASKVTRLKSLALDIDRDTEDQNRYLDGMDSDFTSVTGLLTGSVKRFSTVARSGRDTRKLLCGMAVVLIVAFFILSYLFSRTRT", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9NYM9-1", "uniprot_id": "BET1L_HUMAN", "id": "Q9NYM9-1", "name": "BET1-like protein", "aln": "----------------MAD-WARAQSPGAVEE--------------------ILDRENKRMADSLASKVTRLKSLALDIDRDAEDQNRYLDGMDSDFTSMTSLLTGSVKRFSTMARSGQDNRKLLCGMAVGLIVAFFILSYFLSRART", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q68EL3-1", "uniprot_id": "BET1L_DANRE", "id": "Q68EL3-1", "name": "BET1-like protein", "aln": "----------------MADPWNRG--HGAVDD--------------------MLDAENKRMAENLASKVSRLKSLAYDIDKDAEEQNAYLDGMDSNFLSATGLLTGSVKRFSTMVRSGRDNRKILCYVSVGLVVAFFLLYYLVSRMQN", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P22804-1", "uniprot_id": "BET1_YEAST", "id": "P22804-1", "name": "Protein transport protein BET1", "aln": "MSSRFAGGNAYQRDTGRTQLFGPADGSNSLDDNVSSALGSTDKLDYSQSTLASLESQSEEQMGAMGQRIKALKSLSLKMGDEIRGSNQTIDQLGDTFHNTSVKLKRTFGNMMEMAR--RSGISIKTWLIIFFMVGVLFFWVWIT----", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P43682-1", "uniprot_id": "SFT1_YEAST", "id": "P43682-1", "name": "Protein transport protein SFT1", "aln": "----------------MSN--------SRYSQ---------------------TESNNDRKLEGLANKLATFRNINQEIGDRAVSDSSVINQMTDSLGSMFTDIKNSSSRLTRSLKAGNSIWRMVGLALLIFFILYTLFKLF------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :: . .: : :... :..:: ::.: .:. .. :: : . : . :. : .: : .. : : :.: :: ", "identical_positions": 0, "similar_positions": 45, "identity": "0.0%" }, { "cls_id": "homologset.agr.MGI:1913129", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9Y5S9-1", "uniprot_id": "RBM8A_HUMAN", "id": "Q9Y5S9-1", "name": "RNA-binding protein 8A", "aln": "MADVLDLHEAGGEDFAMDEDGDESIHKLKEKAKKRKGRGFGSEEGSRARMREDYDSVEQDGD---EPGPQRSVEGWILFVTGVHEEATEEDIHDKFAEYGEIKNIHLNLDRRTGYLKGYTLVEYETYKEAQAAMEGLNGQDLMGQPISVDWCFVRGPPKGKRRGGRRRSRSPDRRRR", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9CWZ3-1", "uniprot_id": "RBM8A_MOUSE", "id": "Q9CWZ3-1", "name": "RNA-binding protein 8A", "aln": "MADVLDLHEAGGEDFAMDEDGDESIHKLKEKAKKRKGRGFGSEEGSRARMREDYDSVEQDGD---EPGPQRSVEGWILFVTGVHEEATEEDIHDKFAEYGEIKNIHLNLDRRTGYLKGYTLVEYETYKEAQAAMEGLNGQDLMGQPISVDWCFVRGPPKGKRRGGRRRSRSPDRRRR", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q27W01-1", "uniprot_id": "RBM8A_RAT", "id": "Q27W01-1", "name": "RNA-binding protein 8A", "aln": "MADVLDLHEAGGEDFAMDEDGDESIHKLKEKAKKRKGRGFGSEEGSRARMREDYDSVEQDGD---EPGPQRSVEGWILFVTGVHEEATEEDIHDKFAEYGEIKNIHLNLDRRTGYLKGYTLVEYETYKEAQAAMEGLNGQDLMGQPISVDWCFVRGPPKGKRRGGRRRSRSPDRRRR", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q5D018-1", "uniprot_id": "RBM8A_DANRE", "id": "Q5D018-1", "name": "RNA-binding protein 8A", "aln": "MADVLDLHEAGGEDFPMDEDGDESIHKLKEKAKKRKGRGFGSEEGARSRVREDYDTVEQDGD---EPGPQRSVEGWILFVTGVHEEATEEDVHDKFAEFGEIKNLHLNLDRRTGYLKGYALVEYETYKEAQAAMEGLNGQELMGQPISVDWCFVRGPPKSKRRGGRRRSRSPDRRRR", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9V535-1", "uniprot_id": "RBM8A_DROME", "id": "Q9V535-1", "name": "RNA-binding protein 8A", "aln": "MADVLDIDNA--EEFEVDEDGDQGIVRLKEKAKHRKGRGFGSDSNTREAIHS-YERVRNEDDDELEPGPQRSVEGWILFVTSIHEEAQEDEIQEKFCDYGEIKNIHLNLDRRTGFSKGYALVEYETHKQALAAKEALNGAEIMGQTIQVDWCFVKGP---------KRVKKSEKRRR", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "******:.:* *:* :*****:.* :******:********:..:* ::. *: *.::.* ****************.:**** *:::::**.::*****:*********: ***:******:*:* ** *.*** ::***.*.******:** :* :..::***", "identical_positions": 103, "similar_positions": 48, "identity": "58.19%" }, { "cls_id": "homologset.agr.MGI:1913144", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q86V81-1", "uniprot_id": "THOC4_HUMAN", "id": "Q86V81-1", "name": "THO complex subunit 4", "aln": "MADKMDMSLDDIIKLNRSQRGGRGGGRGRGRAGSQGG--RGGGAQAAARVNRGGGPIRNRPAIARG-AAGGGGRNRPAPYSRPKQLPDKWQHDLFDSGFGGGAGVETG-GKLLVSNLDFGVSDADIQELFA-EFGTLKKAAVHYDRSGRSLGTADVHFERKADALKAMKQYNGVPLDGRPMNIQLVTSQIDAQRRP--AQSVNR--GGMTRN---RGAGGFGGGGGTRRGTRGGARGRGRGAG-RNSKQQ-LSAEELDAQLDAYNARMDTS", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9JJW6-1", "uniprot_id": "ALRF2_MOUSE", "id": "Q9JJW6-1", "name": "Aly/REF export factor 2", "aln": "MADKMDMSLDDIIKLNRNQR----------------------------RVNRGGGPRRNRPAIAR------GGRNRPAPYSRPKPLPDKWQHDLFDSGCGGGEGVETG-AKLLVSNLDFGVSDADIQELFA-EFGTLKKAAVDYDRSGRSLGTADVHFERRADALKAMKQYKGVPLDGRPMDIQLVASQIDPQRRP--AQSGNR--GGMTRS---RGSGGFGG-----RGSQG----RGRGTG-RNSKQQQLSAEELDAQLDAYNARMDTS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9V3E7-1", "uniprot_id": "Q9V3E7_DROME", "id": "Q9V3E7-1", "name": "", "aln": "MVDKIEMSLDDIIKSTRSQKKPQAARGGPGGARKTGGQQRFAGGARRGGANAGGSPRKPGSVLKGPRGGVAAGAVQKAKFPR-GDVNSAWKHDMYDGPKRGAVGGGSGPTRLIVGNLDYGVSNTDIKELFN-DFGPIKKAAVHYDRSGRSLGTADVIFERRADALKAIKQYHGVPLDGRPMTIQLAVSDVAVLTRPVAATDVKRRVGGTAPTSFKRGGGQAGG--TARRGFKRPVGGKPAAGGQRRERKAPPTAEELDAELDSYINDMKI-", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q12159-1", "uniprot_id": "YRA1_YEAST", "id": "Q12159-1", "name": "RNA annealing protein YRA1", "aln": "MSANLDKSLDEIIGSNKAGSN-----------------------RARVGGTRGNGPRRVGKQVGSQ---------RRSLPNRRGPIRKNTRAPPNAVARVAKLLDTTREVKVNVEGLPRDIKQDAVREFFASQVGGVQRVLLSYNERGQSTGMANITFKNGELARRAVERFNGSPIDGGRSRLRLN-LIVDPNQRP--VKSLADRIKAMPQK----GGNAPRP---VKRGPNRKAAMAKSQNKPKREKPAKKSLEDLDKEMADYFEKK---", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* ::: ***:** .: . *..* : : : : * : . : . : :: * .* .:.: ::*:* :.* :::. : *:. *:* * *:: *:. * :*:::::* *:** ::* : ** . . . . . *.. ** . :..: : *:** :: * ", "identical_positions": 36, "similar_positions": 68, "identity": "13.28%" }, { "cls_id": "homologset.agr.MGI:1913150", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q99NH8-1", "uniprot_id": "TREM2_MOUSE", "id": "Q99NH8-1", "name": "Triggering receptor expressed on myeloid cells 2", "aln": "MGPLHQFLLLLITALSQALNTTVLQGMAGQSLRVSCTYDALKHWGRRKAWCRQLGEEGPCQRVVSTHGVWLLAFLKKRNGSTVIADDTLAGTVTITLKNLQAGDAGLYQCQSLRGREAEVLQKVLVEVLEDPLDDQDAGDLWVPEESSSFEGAQVEHSTSR---NQETSFPPTSILLLLACVLLSKFLAASILWAVARGRQKP--GTPVVRGLDCGQ------DAGHQLQILTGPGGT--------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9NZC2-1", "uniprot_id": "TREM2_HUMAN", "id": "Q9NZC2-1", "name": "Triggering receptor expressed on myeloid cells 2", "aln": "MEPLRLLILLFVTELSGAHNTTVFQGVAGQSLQVSCPYDSMKHWGRRKAWCRQLGEKGPCQRVVSTHNLWLLSFLRRWNGSTAITDDTLGGTLTITLRNLQPHDAGLYQCQSLHGSEADTLRKVLVEVLADPLDHRDAGDLWFPGESESFEDAHVEHSISRSLLEGEIPFPPTSILLLLACIFLIKILAASALWAAAWHGQKP--GTHPPSELDCGH------DPGYQLQTLPGLRDT--------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "D3ZZ89-1", "uniprot_id": "D3ZZ89_RAT", "id": "D3ZZ89-1", "name": "Triggering receptor expressed on myeloid cells 2", "aln": "MEPLHVFVLLLVTELSQALNTTVLQGVAGQSLRVSCTYDALRHWGRRKAWCRQLAEEGPCQRVVSTHGVWLLAFLRKQNGSTVITDDTLAGTVTITLRNLQAGDAGLYQCQSLRGREAEVLQKVVVEVLEDPLDDQDAGDLWVPEESESFEGAQVEHSTSS----QVSSCGSPLTYHLPPKEPIRKDLLPTHFHSSPPGLCPPEQASYSQHPLGCGQGQAEAGDTCGQWARLPRCWAPTSDPHWTQRYVREV", "tax_id": 10116, "tax_name": "Rat" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* **: ::**::* ** * ****:**:*****:***.**:::************.*:**********.:***:**:: ****.*:****.**:****:***. **********:* **:.*:**:**** ****.:******.* **.***.*:**** * . .. * . : * * .: : : . * .: *.**: *. * *. . ", "identical_positions": 123, "similar_positions": 53, "identity": "48.81%" }, { "cls_id": "homologset.agr.MGI:1913153", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "B0BN56-1", "uniprot_id": "RT31_RAT", "id": "B0BN56-1", "name": "Small ribosomal subunit protein mS31", "aln": "-------MLHRIPAFIRPRPFSGLP-----------------LSCGNREVSVAASVLPAAGSGAVR---------TENTIQRHFCTSRSICSKKDD---------QSVPANETSQKAAESQGEGKE-TLKKNLLDVIKDMKVQLNTAN-VKTTKPR---GRQPPAHLETAVGRLQKALGEPPRKRNEFLSPELVAAASAVADSLPFDKQTTKSELLKQLQQHEEESRAQTDRQKRRVSFTQIISNMKIAKSPSMRVSSRPQHQIQFDEE-----VDSSLSQEKPADFRRRKCLFKGKRLSIFDVKAFDDEAPEPEAAPSLWEIEFAKQLATVSEQPFGNGFEEMIQWTKEGKLWEFPVNNEAGLDDDGSE-FHEHIFLEKHLEDFP-KQGPIRLFMELVTCGLSKNPYLSVRQKVEHIEWFRNYFNEKRDILKENNIHLTS-----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q61733-1", "uniprot_id": "RT31_MOUSE", "id": "Q61733-1", "name": "Small ribosomal subunit protein mS31", "aln": "-------MLHRIPAFLRPRPFSGLP-----------------LSCGNRDVSVA--VLPAAQSGAVR---------TENNIQRHFCTSRSICSKKVD---------QSVPANEISQKAAESQGRGKE-TLKKDLLDIIKDMKVDLSTAN-VKTPKPR---GRKPSASLEATVDRLQKAPEDPPKKRNEFLSPELVAAASAVADSLPFDKQTTKSELLRQLQQHEEELRAQKDREKRRISFTHIISNMKIAKSPSGRASTRPQHQIQFDED-----MDSSLKQEKPTDFRKRKYLFKGKRLSIFADKAFADEPPEPEASPSLWEIEFAKQLASVADQPFENGFEEMIQWTKEGKLWEFPVNNEAGLDDDGSE-FHEHIFLDKYLEDFP-KQGPIRLFMELVTCGLSKNPYLSVKQKVEHIEWFRNYFNEKRDILKENNIAFT------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q92665-1", "uniprot_id": "RT31_HUMAN", "id": "Q92665-1", "name": "Small ribosomal subunit protein mS31", "aln": "-------MFPRVSTFLPLRPLSRHP-----------------LSSGSPETSAAAIMLLTVRHGTVRYRSSALLARTKNNIQRYFGTNSVICSKKDK---------QSVRTEETSKETSESQDSEKE-NTKKDLLGIIKGMKVELSTVN-VRTTKPP---KRRPLKSLEATLGRLRRATEYAPKKRIEPLSPELVAAASAVADSLPFDKQTTKSELLSQLQQHEEESRAQRDAKRPKISFSNIISDMKVARSATARVRSRPELRIQFDEG-----YDNYPGQEKTDDLKKRKNIFTGKRLNIFDMMAVTKEAPETDTSPSLWDVEFAKQLATVNEQPLQNGFEELIQWTKEGKLWEFPINNEAGFDDDGSE-FHEHIFLEKHLESFP-KQGPIRHFMELVTCGLSKNPYLSVKQKVEHIEWFRNYFNEKKDILKESNIQFN------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A2BEP0-1", "uniprot_id": "A2BEP0_DANRE", "id": "A2BEP0-1", "name": "Small ribosomal subunit protein mS31", "aln": "MYRRLLINIHQVRNGLIHAQKTRTPSVKCKENEGFAHTFWTTGSTSHRPLGTSSICFSDNKESSTSLSDDKEKRREENEAKAEVGTDGQRNTEIKKGPDISNTALTSELETEVELKPKEIKKPEKEKTGKESLLELLGAMKVDVTTVRKVRPPRFPRISEKPSTDQMESTQSMFQDAMAEGSKQR-ETLNPALVAAASAAASTLP-NSQQVESELLQQLRKHEAEPDAQRADRQ---NIGDIIADMKVGKRQMGRSNSRPSNQIRFDDDGQGYTEDRSITSELMNGIHRRKNSFTGKRLNIFSP-GMEQESSE--MGPTLWDIDLANQIVQSTNQMPRNGFEEMMQWTKEGKLWQYPINNEAGLDEEASVPFHEHVFLEKHLESFP-RQGPVRHFMELVITGLSKNHHLTVQQKQEHIAWFRDYFQQKDDVMKEAQA---------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VUX1-1", "uniprot_id": "Q9VUX1_DROME", "id": "Q9VUX1-1", "name": "Small ribosomal subunit protein mS31", "aln": "--------MLAVRSSQRLGLRSLLP-----------------SAFKNVGLVNYSSSQSKNDDGYSS-------SDDEKPTKKKEEPVETAAQRLNR--------LLGTMQATDQLSASDFPRPGDANRKRREAQKQEAAAKNVLTAAKNIASMLGT-----SESDKKQTESELLAKLLGHGSESSSAATGENQTADVSGSP---SGDKELNLSDIIVGMKIDRRQQPQQVEQTRGEYVRRSLASRFKPQNRDGAYQRSQRQ------------------TKREAESFTGSVNLYGGEPLGIFKD----TQLPISNDILSTWSQLSERELSLQASHPPANYFEQMVLWTDQKKVWRFPINNEQDWEDEHNVDFSEHIFLEQHLEDWCPSKGPIRHFMELVCVGLSKNPYLTAQEKKDHIFWFRDYFQAKKDILRDLISKEPSKSISA", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : : * : . :: : . . . . .. : . :.. * :.:.. : . :: : ... . .* .*. . . :.: *::: :: .. : * : : : :* . :: . .. .: : *: *.** : . : *. .:: .: * **::: **.: *:*.:*:*** . ::: . * **:**:::**.: :**:* ***** ***** :*:.::* :** ***:**: * *:::: ", "identical_positions": 54, "similar_positions": 107, "identity": "12.11%" }, { "cls_id": "homologset.agr.MGI:1913192", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q6AXT1-1", "uniprot_id": "FHL5_RAT", "id": "Q6AXT1-1", "name": "Four and a half LIM domains protein 5", "aln": "MTSTQFDCQYCTASLLGKKYVLKDDNLYCISCYDRIFSNYCEQCKEPIESDSKDLCYKNRHWHEGCFRCNKCHHSLVEKPFVAKDERLLCTDCYSNECSSKCFHCKRTIMPGSRKMEFKGNYWHETCFVCEHCRQPIGTKPLISKESGNYCVPCFEKEFAHYCNFCKKVITSGGITFRDQIWHKECFLCSG-CRKELYEEAFMSKDDFPFCLDCYNHLYAKKCAACTKPITGLRGAKFICFQDRQWHSECFNCGKCSVSLVGEGFLTQNMEILCRKCGSGADTDM-----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9WTX7-1", "uniprot_id": "FHL5_MOUSE", "id": "Q9WTX7-1", "name": "Four and a half LIM domains protein 5", "aln": "MTSSQFDCQYCTSSLIGKKYVLKDDNLYCISCYDRIFSNYCEQCKEPIESDSKDLCYKNRHWHEGCFRCNKCHHSLVEKPFVAKDDRLLCTDCYSNECSSKCFHCKRTIMPGSRKMEFKGNYWHETCFVCEHCRQPIGTKPLISKESGNYCVPCFEKEFAHYCNFCKKVITSGGITFRDQIWHKECFLCSG-CRKELYEEAFMSKDDFPFCLDCYNHLYAKKCAACTKPITGLRGAKFICFQDRQWHSECFNCGKCSVSLVGEGFLTHNMEILCRKCGSGADTDA-----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q5TD97-1", "uniprot_id": "FHL5_HUMAN", "id": "Q5TD97-1", "name": "Four and a half LIM domains protein 5", "aln": "MTTAHFYCQYCTASLLGKKYVLKDDSPYCVTCYDRVFSNYCEECKKPIESDSKDLCYKDRHWHEGCFKCTKCNHSLVEKPFAAKDERLLCTECYSNECSSKCFHCKRTIMPGSRKMEFKGNYWHETCFVCENCRQPIGTKPLISKESGNYCVPCFEKEFAHYCNFCKKVITSGGITFCDQLWHKECFLCSG-CRKDLCEEQFMSRDDYPFCVDCYNHLYANKCVACSKPISGLTGAKFICFQDSQWHSECFNCGKCSVSLVGKGFLTQNKEIFCQKCGSGMDTDI-----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8MLQ2-1", "uniprot_id": "Q8MLQ2_DROME", "id": "Q8MLQ2-1", "name": "LIM zinc-binding domain-containing protein", "aln": "----------------------------------------------------------------------------------------------MS--ASICCRCNEKIWP--RAVCSLGKTYHPHHFTCKECGLVVDPKLFFAVDDDVVCSECYLDKHAARCSACRTPILERGVAAAERKWHEKCFRCVS-CSKSLVSASFFEVNGYLFCKAHFRELFSSRCAGCEKPID----RRAVVALSTKWHAKCFKCHHCRKRISAREFWIENGQPICAACQTVVPSPRNLSAQ", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VXC1-1", "uniprot_id": "Q9VXC1_DROME", "id": "Q9VXC1-1", "name": "LIM zinc-binding domain-containing protein", "aln": "----------------------------------------------------------------------------------------------MSEQPSICHKCNEVIQL--RIITALGKTWHPEHFVCKDCQCPITEASFNINDGQPVCSACFVSNYSGICHGCKRPILERTIKAMGETWHEECFLCRGPCMQQLAGSSFYEHDGLPYCRTDFEHMFAARCGNCKAPIT----ENAIVALDAKWHRECFKCKKCKTPITASSFVVEDNQPLCKACSD-----------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . .* * :*:. * * : *: :* *.*:.* : : :. * *: .:.: * *: * . : . **::** * . * :.* * . :. :* :..::: :* * ** . : . :** :**:* :* : . * .: : :* * ", "identical_positions": 37, "similar_positions": 53, "identity": "12.76%" }, { "cls_id": "homologset.agr.MGI:1913208", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q4AE70-1", "uniprot_id": "CARM1_RAT", "id": "Q4AE70-1", "name": "Histone-arginine methyltransferase CARM1", "aln": "MAAAAATAVGPGAGSAGVAGPGGAGPCATVSVFPGARLLTIGDANGEIQRHAEQQALRLEVRAGPDAAGIALYSHED--VCVFKCSVSRETECSRVGRQSFIITLGCNSVLIQFATPHDFCSFYNILKTCRGHTLERSVFSERTEESSAVQYFQFYGYLSQQQNMMQDYVRTGTYQRAILQNHTDFKDKIVLDVGCGSGILSFFAAQAGARKIYAVEASTMAQHAEVLVKSNNLTDRIVVIPGKVEEVSLPEQVDIIISEPMGYMLFNERMLESYLHAKKYLKPSGNMFPTIGDVHLAPFTDEQLYMEQFTKANFWYQPSFHGVDLSALRGAAVDEYFRQPVVDTFDIRILMAKSVKYTVNFLEAKEGDLHRIEIPFKFHMLHSGLVHGLAFWFDVAFIGSIMTVWLSTAPTEPLTHWYQVRCLFQSPLFAKAGDTLSGTCLLIANKRQSYDISIVAQVDQTGSKSSNLLDLKNPFFRYTGTTPSPPPGSHYTSPSENMWNTGSTYNLSSGVAVAGMPTAYDLSSVIAG-GSSVGHNNLIPL------ANTGIVNHTHSRMGSIMSTGIVQGNRVAGPWAGDLPPGLRTRSSYQWGPGRLRGHAGSSVPMTCPTGSSGAQG-GGGSSSAHYAVNNQFTMGGPAISMASPMSIPTNTMHYGS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9WVG6-1", "uniprot_id": "CARM1_MOUSE", "id": "Q9WVG6-1", "name": "Histone-arginine methyltransferase CARM1", "aln": "MAAAAATAVGPGAGSAGVAGPGGAGPCATVSVFPGARLLTIGDANGEIQRHAEQQALRLEVRAGPDAAGIALYSHED--VCVFKCSVSRETECSRVGRQSFIITLGCNSVLIQFATPHDFCSFYNILKTCRGHTLERSVFSERTEESSAVQYFQFYGYLSQQQNMMQDYVRTGTYQRAILQNHTDFKDKIVLDVGCGSGILSFFAAQAGARKIYAVEASTMAQHAEVLVKSNNLTDRIVVIPGKVEEVSLPEQVDIIISEPMGYMLFNERMLESYLHAKKYLKPSGNMFPTIGDVHLAPFTDEQLYMEQFTKANFWYQPSFHGVDLSALRGAAVDEYFRQPVVDTFDIRILMAKSVKYTVNFLEAKEGDLHRIEIPFKFHMLHSGLVHGLAFWFDVAFIGSIMTVWLSTAPTEPLTHWYQVRCLFQSPLFAKAGDTLSGTCLLIANKRQSYDISIVAQVDQTGSKSSNLLDLKNPFFRYTGTTPSPPPGSHYTSPSENMWNTGSTYNLSSGVAVAGMPTAYDLSSVIAG-GSSVGHNNLIPL------ANTGIVNHTHSRMGSIMSTGIVQG-------------------------------------------SSGAQG-GGGSSSAHYAVNNQFTMGGPAISMASPMSIPTNTMHYGS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q86X55-3", "uniprot_id": "CARM1_HUMAN", "id": "Q86X55-3", "name": "Histone-arginine methyltransferase CARM1", "aln": "-MAAAAAAVGPGAGGAGSAVPGGAGPCATVSVFPGARLLTIGDANGEIQRHAEQQALRLEVRAGPDSAGIALYSHED--VCVFKCSVSRETECSRVGKQSFIITLGCNSVLIQFATPNDFCSFYNILKTCRGHTLERSVFSERTEESSAVQYFQFYGYLSQQQNMMQDYVRTGTYQRAILQNHTDFKDKIVLDVGCGSGILSFFAAQAGARKIYAVEASTMAQHAEVLVKSNNLTDRIVVIPGKVEEVSLPEQVDIIISEPMGYMLFNERMLESYLHAKKYLKPSGNMFPTIGDVHLAPFTDEQLYMEQFTKANFWYQPSFHGVDLSALRGAAVDEYFRQPVVDTFDIRILMAKSVKYTVNFLEAKEGDLHRIEIPFKFHMLHSGLVHGLAFWFDVAFIGSIMTVWLSTAPTEPLTHWYQVRCLFQSPLFAKAGDTLSGTCLLIANKRQSYDISIVAQVDQTGSKSSNLLDLKNPFFRYTGTTPSPPPGSHYTSPSENMWNTGSTYNLSSGMAVAGMPTAYDLSSVIAS-GSSVGHNNLIPL------ANTGIVNHTHSRMGSIMSTGIVQG-------------------------------------------SSGAQGSGGGSTSAHYAVNSQFTMGGPAISMASPMSIPTNTMHYGS", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6DC04-1", "uniprot_id": "CARM1_DANRE", "id": "Q6DC04-1", "name": "Histone-arginine methyltransferase CARM1", "aln": "---------------------------MAVSVFSGVRLLSIGDANGDIQRHSEQQPLRLEIKMNQDAAQIILSNNEE--TCVFKCTVLRETECSRVGKQSFIITLGCNSVLLQFASPADFSSFYNLLKICRGQKGDRSVFSDRTEESSAVQYFQFYGYLSQQQNMMQDYVRTGTYQRAILQNHTDFKDKVVLDVGCGSGILSFFAAQAGARKVYAVEASTMAQHAEVLVNSNRLSERVVVIPGKVEEVSLPEQVDIIISEPMGYMLFNERMLESYLHAKKFLKPSGKMFPTIGDVHLAPFTDEQLYMEQFTKANFWYQPSFHGVDLSALRGAAVDEYFRQPIVDTFDIRILMAKSVKYTVNFLEAKEEDLYKIEIPFKFHMMHSGLVHGLAFWFDVAFIGSVMTVWLSTAPTEPLTHWYQVRCLLQSPLFAKAGDTMSGTALLIANKRQSYDISIVAQVDQTGSKSSNLLDLKNPFFRYTGTTPAPPPGSHYSSPSENMWNTGGTYSMSQGMAVSGMPTAYDLSTVIGGSGTTVSHNNLIPLGTDTHALNTGIVNHTHSRMGSIMSTGIVQG-------------------------------------------ATTAQQ-GPSSASLHYPVTNQFTMGGPAISMASPMAIPSNTMHYGS", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VH48-1", "uniprot_id": "CARM1_DROME", "id": "Q9VH48-1", "name": "Probable histone-arginine methyltransferase CARMER", "aln": "-MSSLRPEEARKLATAASVSP------LSNCQFCGVVISSIADEQKLEFTNKYKGSCTLLCSYDSQGVVLRVVSDDDRSHVLKEYMIAADTDAAQMGRRSYAVSLDADNLVLRFASEQDQQLFRKVVENVK-HLRPKSVFSQRTEESSASQYFQFYGYLSQQQNMMQDYVRTSTYQRAILGNAVDFQDKIVLDVGAGSGILSFFAVQAGAAKVYAIEASNMAQYAQQLVESNNVQHKISVIPGKIEEIELPEKVDVIISEPMGYMLYNERMLETYLHARKWLKPQGKMYPTHGDLHIAPFSDESLYSEQYNKANFWYQSAFHGVDLTTLHKEGMKEYFRQPIVDTFDIRICMAKSVRHVCDFLNDKEDDLHLISIPLEFHILQTGICHGLAFWFDVEFSGSSQNVWLSTSPTAPLTHWYQVRCLLPMPIFIKQGQTLTGRVLLEANRRQSYDVTIDLHIEGTLISSSNTLDLKNPYFRYTGAPVQAPPGTSTQSPSEQYWTQVDTQ---------------------------------------------GSRNSSSMLNGGISVNGIGEG-----------------------------------------------------------------------------MDITHGLMHPH-", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . * *. : :*.* : : : . * . :.. : : ..:: : : : :*:.:::*::*: ::*..:.::::**: * * :::: : : :****:******* **********************.******* * .**:**:*****.*********.**** *:**:***.***:*: **:**.: .:: *****:**:.***:**:**********:******:****:*:***.*:*:** **:*:***:**.** **:.*******.:******::*: .:.******:******** *****::. :**: ** **: *.**::**::::*: ********* * ** .*****:** ***********: *:* * *:*::* ** **:*****::* ::: * .*** ******:*****:. .***: ****: *. .* * * : *.* .** :* * *. . ** ", "identical_positions": 268, "similar_positions": 137, "identity": "40.54%" }, { "cls_id": "homologset.agr.MGI:1913224", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q3TC93-1", "uniprot_id": "H1BP3_MOUSE", "id": "Q3TC93-1", "name": "HCLS1-binding protein 3", "aln": "MQSPAVLRTSRQVQNAHTGLDLSVPQHQEVRGKMMSGHVEYQILVVTRLAVFKSAKHRPEDVVQFLVSKKYSEIEEFYQKLYSCYPAASLPPLPRKVLFVGESDIRERRAMFDEILRCVSKDAQLAGSPELLEFLG---TRAPGATGLATRDPSVLDDTASQPGDSDEAFDFFEQQDEVQ---PPTLGLSSKDVEKSLVGEEEEEEEEEEVLDPLGIMRSKKPKKRPEVAVRPK--PAPRLTIFDEEVDPDAGLFSSDKKVSETRRPLE--TTQDSLKLFDDPDLGGAVSLGDPLLLPAASESRGPTSRPEHGDAS-KELFRVEEDLDLILNLGSEPKPKPQTKPKPLVPAKPALPRKPTLPASVGPSEPGSGPQK-QQQIQAMDEMDILQYIRDHDTLAQDSPSLF--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D4A6D9-1", "uniprot_id": "D4A6D9_RAT", "id": "D4A6D9-1", "name": "HCLS1-binding protein 3", "aln": "MQSPAVLVTSRQVQNAHTGLDLTVPQHQEVRGKMMSGHVEYQILVVTRLAVFKSAKHRPEDVVQFLVSKKYSEIEEFYQKLYSRYPEASLPPLPRKVLFVGESDIRERRAMFDEILRCVSKDAQLAGSPELLEFLGTQGTRSPGATGFATRDPSVLDETASRPGDSDEAFDFFEQQDEVQ---PPTLGLSNKNVEKSLE----EEEEEEEILDPLGIMRSKKPKKHQEVAMRTK--PSPRLTIFDEEVDPDEGLFSSDKKVSP-RRPLG--TTEDPLKLFDDPDLGGAVSLGDPLLLPAAHESRGPTSSPEHRDAS-KELFRVEEDLDQILNLGSEPKPKPQLKPKPLVPSKPALPRKPTVPPAVGPSGTGAGPQK-QQQIQAMDEMDILQYIRDQDTLAQDSPSLF--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q53T59-1", "uniprot_id": "H1BP3_HUMAN", "id": "Q53T59-1", "name": "HCLS1-binding protein 3", "aln": "MQSPAVLVTSRRLQNAHTGLDLTVPQHQEVRGKMMSGHVEYQILVVTRLAAFKSAKHRPEDVVQFLVSKKYSEIEEFYQKLSSRYAAASLPPLPRKVLFVGESDIRERRAVFNEILRCVSKDAELAGSPELLEFLG---TRSPGAAGLTSRDSSVLDGTDSQTGNDEEAFDFFEEQDQVAEEGPPVQSLKGEDAEESLE--------EEEALDPLGIMRSKKPKKHPKVAVKAK--PSPRLTIFDEEVDPDEGLFGPGRKLSP-QDPSEDVSSVDPLKLFDDPDLGGAIPLGDSLLLPAACESGGPTPSLSHRDAS-KELFRVEEDLDQILNLGAEPKPKPQLKPKPPVAAKPVIPRKPAVPPKAGPAEAVAGQQKPQEQIQAMDEMDILQYIQDHDTPAQAAPSLF--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F6PCK0-1", "uniprot_id": "F6PCK0_DANRE", "id": "F6PCK0-1", "name": "", "aln": "--MSDGRITSRPLQNEATGIDLHVPLYQEIRGSVITGHVEYQIVVVTCLSSFKSAIHKTGDVLQFVVSKKYSEIEQLYYSLKTKYPSIHLPPMPRKALFVSETDLCNRRVAFDELVKFLSKHPLLANCPELLEFLG---------AKTTAVEVKTINKPDFIEKEVDDGLDFFESGDPLQ---KPSE--------------------DVELLDPLGSEWLKKDVKPKDVCPVGKCVPKPKSETLFEEED-DTELFSPAK--------------KGHVMLFDNTPLRSIDSS------PFSNTSNGIKMTESKVDEDIEELLSVEMDLHKHLSVSKTVRCRPDTAMNP---MKPKVKSKPVASERTSNLTQATDLQL--SGTEVMNQMDILQYIQQNDLPASEDLDLFKS", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . *** :** **:** ** :**:**.:::*******:*** *: **** *:. **:**:*********::* .* : *. ***:***.***.*:*: :**. *:*::: :**.. **..******** : :: : ..:: . : ::.:****. * : * : * ***** ** * .*. * * *: : ** * * **.. : . : ***:. * . . * : * * . .: * . :**: ** **. *.:. : :*: :* ** : **. . .. :. * . :.*::*******:::* *. .** ", "identical_positions": 133, "similar_positions": 98, "identity": "32.52%" }, { "cls_id": "homologset.agr.MGI:1913266", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZGQ2-1", "uniprot_id": "D3ZGQ2_RAT", "id": "D3ZGQ2-1", "name": "Thymidine kinase 2, mitochondrial", "aln": "MLLRSLRSWAARSLRSMGPGSSGSPGSLDSGAGP----LWAPRRACPPDKDREKDKEKKAVVCIEGNIASGKTTCLEFFSN-TTDVEVLMEPVLKWRNVHGHNPLSLMYHNASRWGLTLQTYVQLTMLDQHTRPQMSPVRLMERSIYSARYIFVENLYRSGKMPEVDYAILSEWFDWIIKNIDVSVDLIVYLRTTPEICYQRLKMRCREEEKVIPVEYLSAIHHLYEEWLVTGSLFPAAAPVLVIEADHNLEKMLELFEQNRARILTPENWKHGP---------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9R088-1", "uniprot_id": "KITM_MOUSE", "id": "Q9R088-1", "name": "Thymidine kinase 2, mitochondrial", "aln": "MLLRSLRSWAARSPRSVGPGSSGSPGSLDSGAGP----LWAPRRAWPPDKDRENDKEKKAVVCIEGNIASGKTTCLEFFSN-TTDVEVLMEPVLKWRNVHGHNPLSLMYHDASRWGLTLQTYVQLTMLDQHTRPQMSPVRLMERSIYSARYIFVENLYRGGKMPEVDYAILSEWFDWIVRNIDVSVDLIVYLRTTPEICYQRLKMRCREEEKVIPMEYLHAIHRLYEEWLVNGSLFPAAAPVLVIEADHNLEKMLELFEQNRARILTPENWKHGP---------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O00142-1", "uniprot_id": "KITM_HUMAN", "id": "O00142-1", "name": "Thymidine kinase 2, mitochondrial", "aln": "MLLWPLRGWAARALRCFGPGSRGSP---ASGPGP----RRVQRRAWPPDKEQE--KEKKSVICVEGNIASGKTTCLEFFSN-ATDVEVLTEPVSKWRNVRGHNPLGLMYHDASRWGLTLQTYVQLTMLDRHTRPQVSSVRLMERSIHSARYIFVENLYRSGKMPEVDYVVLSEWFDWILRNMDVSVDLIVYLRTNPETCYQRLKKRCREEEKVIPLEYLEAIHHLHEEWLIKGSLFPMAAPVLVIEADHHMERMLELFEQNRDRILTPENRKHCP---------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1N0Z5-1", "uniprot_id": "A0A8M1N0Z5_DANRE", "id": "A0A8M1N0Z5-1", "name": "Thymidine kinase 2, mitochondrial", "aln": "MIVNSFKGLCRVVLPLYSHKSLSTNILVRHRAALGKHLLGHWRSSTSHGKLVRNGEGKKSVICLEGNIASGKTTCLEYFSK-TSDIEVLTEPVSKWRNVQGCNPLGLMYQDPTRWGLTLQTYVQLTMLDQHVSPMTAPIRMMERSIYSAKYIFVENLYKSGKMPEVDFAVLSEWFEWIIKNISLPVDLIVYLQTSPQTCHERLKQRCREEEKVIPLEYLESIHNLYEDWLIHQKSFHVPAPVLVIPADHDLKKMLHQFEENREKILMAR---------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9XZT6-1", "uniprot_id": "DNK_DROME", "id": "Q9XZT6-1", "name": "Deoxynucleoside kinase", "aln": "---MAEAASCARKGTKYAEGT------------------------------------QPFTVLIEGNIGSGKTTYLNHFEKYKNDICLLTEPVEKWRNVNGVNLLELMYKDPKKWAMPFQSYVTLTMLQSHTAPTNKKLKIMERSIFSARYCFVENMRRNGSLEQGMYNTLEEWYKFIEESIHVQADLIIYLRTSPEVAYERIRQRARSEESCVPLKYLQELHELHEDWLIHQRR-PQSCKVLVLDADLNLENIGTEYQRSESSIFDAISSNQQPSPVLVSPSKRQRVAR", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . . . . : : .: :****.***** *:.*.: .*: :* *** *****.* * * ***::..:*.:.:*:** ****: *. * :::*****.**:* ****: :.*.: : : *.**:.:* ..: : .***:**:*.*: .::*:: *.*.**. :*::** :*.*:*:**: .. ***: ** .::.: ::... *: . ", "identical_positions": 80, "similar_positions": 86, "identity": "27.59%" }, { "cls_id": "homologset.agr.MGI:1913272", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9JIN6-1", "uniprot_id": "KCMB4_MOUSE", "id": "Q9JIN6-1", "name": "Calcium-activated potassium channel subunit beta-4", "aln": "MAKLRVSYEYTEAEDKSIRLGLFLIVSGILSLFIFGFCWLSPALQDLQATAANCTVLSVQQIGEVFECTFTCGTDCRGTSQYPCVQVYVNNSESNSRALLHSDQHQLLTNPKCSYIPPCKRENQKNSESVMNWQQYWKDEIGSQPFTCYFNQHQRPEDVLLQRTHDEIALLHCFLWPVVAFVVGVLIVVLTICAKSLAVKAEAMKKRKFS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9ESK8-1", "uniprot_id": "KCMB4_RAT", "id": "Q9ESK8-1", "name": "Calcium-activated potassium channel subunit beta-4", "aln": "MAKLRVSYEYTEAEDKSIRLGLFLIVSGILSLFIFGFCWLSPALQDLQATAANCTVLSVQQIGEVFECTFTCGTDCRGTSQYPCVQVYVNNSESNSRALLHSDQHQLLTNPKCSYIPPCKRENQKNSESVMNWQQYWKDEIGSQPFTCYFNQHQRPEDVLLQRTHDEIVLLHCFLWPVVAFVVGVLIVVLTICAKSLAVKAEAMKKRKFS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q86W47-1", "uniprot_id": "KCMB4_HUMAN", "id": "Q86W47-1", "name": "Calcium-activated potassium channel subunit beta-4", "aln": "MAKLRVAYEYTEAEDKSIRLGLFLIISGVVSLFIFGFCWLSPALQDLQATEANCTVLSVQQIGEVFECTFTCGADCRGTSQYPCVQVYVNNSESNSRALLHSDEHQLLTNPKCSYIPPCKRENQKNLESVMNWQQYWKDEIGSQPFTCYFNQHQRPDDVLLHRTHDEIVLLHCFLWPLVTFVVGVLIVVLTICAKSLAVKAEAMKKRKFS", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "******:******************:**::******************** **********************:*****************************:********************** *****************************:****:******.********:*:******************************", "identical_positions": 197, "similar_positions": 11, "identity": "93.81%" }, { "cls_id": "homologset.agr.MGI:1913275", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "G3V7Z1-1", "uniprot_id": "G3V7Z1_RAT", "id": "G3V7Z1-1", "name": "RNA 3'-terminal phosphate cyclase-like protein", "aln": "---MATQAHSLSYAGCNFLRQRLVLSTLSGRPVKIRRIRARDD-NPGLRDFEASFIRLLDKITNGSRIEINQTGTTLYYQPGLLYGGSVEHDCSVLRGIGYYLEALLCLAPFMKHPLKIVLRGVTNDQVDPSVDVLKATALPLLKQFGIDGESFELKILRRGMPPGGGGEVLFSCP-VRKVLKPVQLTDPGKIKRIRGMAYSVRVSPQMANRIVDSARGILNKFIPDIYIYTDHMKGVNSGKSPGFGLSLVAETTNG--TFLSAELASNP--QGQGAAVLPEDLGRNCAKLLLEEIYRGGCVDSTSQSLVLLLMTLGQQDVSKVLLG--PLSPYTIEFLRHLKSFFQVMFKVETKPCG-----EELKGGDKVLMTCVGIGFSNLSKTLK", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9JJT0-1", "uniprot_id": "RCL1_MOUSE", "id": "Q9JJT0-1", "name": "RNA 3'-terminal phosphate cyclase-like protein", "aln": "---MATQAHSLSYAGCNFLRQRLVLSTLSGRPVKIRRIRARDD-NPGLRDFEASFIRLLDKITNGSRIEINQTGTTLYYQPGLLYGGSVEHDCSVLRGIGYYLEALLCLAPFMKHPLKIVLRGVTNDQVDPSVDVLKATALPLLKQFGIDGESFELKILRRGMPPGGGGEVLFSCP-VRKVLKPVQLTDPGKIKRIRGMAYSVRVSPQMANRIVDSARSILNKFIPDIYIYTDHMKGVSSGKSPGFGLSLVAETTNG--TFLSAELASNP--QGQGAAVLPEDLGRNCAKLLLEEIYRGGCVDSTNQSLVLLLMTLGQQDVSKVLLG--PLSPYTIEFLRHLKSFFQVMFKVETKPCG-----EELKGGDKVLMTCVGIGFSNLSKTLK", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9Y2P8-1", "uniprot_id": "RCL1_HUMAN", "id": "Q9Y2P8-1", "name": "RNA 3'-terminal phosphate cyclase-like protein", "aln": "---MATQAHSLSYAGCNFLRQRLVLSTLSGRPVKIRKIRARDD-NPGLRDFEASFIRLLDKITNGSRIEINQTGTTLYYQPGLLYGGSVEHDCSVLRGIGYYLESLLCLAPFMKHPLKIVLRGVTNDQVDPSVDVLKATALPLLKQFGIDGESFELKIVRRGMPPGGGGEVVFSCP-VRKVLKPIQLTDPGKIKRIRGMAYSVRVSPQMANRIVDSARSILNKFIPDIYIYTDHMKGVNSGKSPGFGLSLVAETTSG--TFLSAELASNP--QGQGAAVLPEDLGRNCARLLLEEIYRGGCVDSTNQSLALLLMTLGQQDVSKVLLG--PLSPYTIEFLRHLKSFFQIMFKIETKPCG-----EELKGGDKVLMTCVGIGFSNLSKTLK", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P56175-1", "uniprot_id": "RCL1_DROME", "id": "P56175-1", "name": "Probable RNA 3'-terminal phosphate cyclase-like protein", "aln": "MPPIAQEGNCLIYRGSNFLKQRLILACLSGKPVKISQIRSEDETAPGLREYEISLIRLLDKITNGTKIELNPAGTSVMFSPGLLHGGQLNHDCCVQRGIGYYLDALIALGPFCKSPLQCTLRGVTNSKDSPSVDHIKGAALSLLKRFLLVDEGLELKVVRRGVAPLGGGEIIFRCP-VRKSLRAIQFQSQGMVKRIRGTVYACKVSPAMANRTVEAAKGCMLKFLPDVYIYTDQNKGKMSGNSPGFGICLIAETTDG--VCFAADCCSNTREESEDTPSIPENLGKEVALRLLDEIYRGGCVDSSYQWLAALYIALGQKHVSKFLTG--ALSNYTVHFLQHLRDFFSITFKLENPEAEDEDEAENVRGAQKVLMACVGIGYTNINKRVI", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q08096-1", "uniprot_id": "RCL1_YEAST", "id": "Q08096-1", "name": "rRNA processing protein RCL1", "aln": "--MSSSAPKYTTFQGSQNFRLRIVLATLSGKPIKIEKIRSGDL-NPGLKDYEVSFLRLIESVTNGSVIEISYTGTTVIYRPGIIVGGASTHICPSSKPVGYFVEPMLYLAPFSKKKFSILFKGITASHNDAGIEAIKWGLMPVMEKFGVR--ECALHTLKRGSPPLGGGEVHLVVDSLIAQPITMHEIDRPIISSITGVAYSTRVSPSLVNRMIDGAKKVLKNLQCEVNITADVWRGENSGKSPGWGITLVAQSKQKGWSYFAEDIGDAG--------SIPEELGEKVACQLLEEISKSAAVGRNQLPLAIVYMVIGKEDIGRLRINKEQIDERFIILLRDIKKIFNTEVFLKP---------VDEADNEDMIATIKGIGFTNTSKKIA", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : : *.: :: *::*: ***:*:** :**: * ***:::* *::**::.:***: **:. :**:: : **:: ** * * : :**:::.:: *.** * :. ::*:* .: ...:: :* :.::::* : *: ::** .* ****: : : .:: . :. * * .*: :*** :.** ::.*: : :: :: * :* :* **:***:*: *:*::.. :: : . :**:**.: * **:** :...*. . *. : :.:*::.:.:. . :. : :*:.::.:*. . :: : . :.:: : ***::* .* : ", "identical_positions": 89, "similar_positions": 151, "identity": "22.88%" }, { "cls_id": "homologset.agr.MGI:1913276", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q5XI55-1", "uniprot_id": "NGLY1_RAT", "id": "Q5XI55-1", "name": "Peptide-N(4)-(N-acetyl-beta-glucosaminyl)asparagine amidase", "aln": "----MASATLGSSSSSASPAVAELCQNTPETFLEASKLLLTYADNILRNPSDEKYRSIRIGNTAFSTRLLPVRGAVECLFEMGFEEG--ETHLIFPKKASVEQLQKIRDLIAVERRSRLDGS--SQKVEFSQHPAA-VRLPAEQPEDPTGLMQHSGNQPGQPLSLPSAPLVVGDSTIFKVLQSNIQHVQLYENPVLQEKALACIPVNELKRKSQEKLFRARKLDKGTKVSDE-----DFLLLELLHWFKEEFFHWVNNVVCSRCGR---ETRSRDEALPPNDDELKWGAKNVEDHYCDACQLSNRFPRYNNPEKLLETRCGRCGEWANCFTLCCRALGFEARYVWDYTDHVWTEVYSPSQQRWLHCDACEDVCDKPLLYEIGWGKKLSYIIAFSKDEVVDVTWRYSCKHEEVMSRRTKVKEELLRETINGLNKQRQLLLSESRRKELLQRIIVELVEFISPKTPRPGELGGRVSGSLAWRVARGETCLE-----RKEILFIPSENEKISKQFHLRYDIVRDRYIRVSDNN------ANISGWENGVWKMESIFRKVEKDWNMVYLARKEGSSFAYISWKFECGSAGLKVDNVSIRTSSQSFETGSVRWKLRSEMAQVNLLGDRNLRSYDDFCGATEVTLEAELSRGDGDVAWQHTQLFRQSLNDHAENGLEIIITFSDL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9JI78-1", "uniprot_id": "NGLY1_MOUSE", "id": "Q9JI78-1", "name": "Peptide-N(4)-(N-acetyl-beta-glucosaminyl)asparagine amidase", "aln": "----MASATLGSSSSSASPAVAELCQNTPETFLEASKLLLTYADNILRNPSDEKYRSIRIGNTAFSTRLLPVRGAVECLFEMGFEEG--ETHLIFPKKASVEQLQKIRDLIAIERSSRLDGS--SKKVQFSQHPAA-AKLPLEQSEDPAGLIRHSGNQTGQLPSLPSAPMVVGDSTILKVLQSNIQHVQLYENPVLQEKALTCIPVSELKRKAQEKLFRARKLDKGTNVSDE-----DFLLLELLHWFKEEFFRWVNNIVCSKCGG---ETRSRDEALLPNDDELKWGAKNVENHYCDACQLSNRFPRYNNPEKLLETRCGRCGEWANCFTLCCRALGFEARYVWDYTDHVWTEVYSPSQQRWLHCDACEDVCDKPLLYEIGWGKKLSYIIAFSKDEVVDVTWRYSCKHDEVMSRRTKVKEELLRETINGLNKQRQLSLSESRRKELLQRIIVELVEFISPKTPRPGELGGRVSGSLAWRVARGETGLE-----RKEILFIPSENEKISKQFHLRYDIVRDRYIRVSDNN------INISGWENGVWKMESIFRKVEKDWNMVYLARKEGSSFAYISWKFECGSAGLKVDTVSIRTSSQSFESGSVRWKLRSETAQVNLLGDKNLRSYNDFSGATEVTLEAELSRGDGDVAWQHTQLFRQSLNDSGENGLEIIITFNDL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q96IV0-1", "uniprot_id": "NGLY1_HUMAN", "id": "Q96IV0-1", "name": "Peptide-N(4)-(N-acetyl-beta-glucosaminyl)asparagine amidase", "aln": "----MAAAALGSSSGSASPAVAELCQNTPETFLEASKLLLTYADNILRNPNDEKYRSIRIGNTAFSTRLLPVRGAVECLFEMGFEEG--ETHLIFPKKASVEQLQKIRDLIAIERSSRLDGSNKSHKVKSSQQPAASTQLPTTPSSNPSGLNQHTRNRQGQSSDPPSASTVAADSAILEVLQSNIQHVLVYENPALQEKALACIPVQELKRKSQEKLSRARKLDKGINISDE-----DFLLLELLHWFKEEFFHWVNNVLCSKCGG---QTRSRDRSLLPSDDELKWGAKEVEDHYCDACQFSNRFPRYNNPEKLLETRCGRCGEWANCFTLCCRAVGFEARYVWDYTDHVWTEVYSPSQQRWLHCDACEDVCDKPLLYEIGWGKKLSYVIAFSKDEVVDVTWRYSCKHEEVIARRTKVKEALLRDTINGLNKQRQLFLSENRRKELLQRIIVELVEFISPKTPKPGELGGRISGSVAWRVARGEMGLQ-----RKETLFIPCENEKISKQLHLCYNIVKDRYVRVSNNN------QTISGWENGVWKMESIFRKVETDWHMVYLARKEGSSFAYISWKFECGSVGLKVDSISIRTSSQTFQTGTVEWKLRSDTAQVELTGDNSLHSYADFSGATEVILEAELSRGDGDVAWQHTQLFRQSLNDHEENCLEIIIKFSDL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q503I8-1", "uniprot_id": "NGLY1_DANRE", "id": "Q503I8-1", "name": "Peptide-N(4)-(N-acetyl-beta-glucosaminyl)asparagine amidase", "aln": "--------------MPGSQGVLALCENTTEVFLDVSKLLITYADNILRNPNEEKYRSIRIGNPTFSTKLLPVKGAVECLFEMGFEEA--ETHLVFPRSASVEKLRQVRETIAAERDQRLGAS----NTASSPQNASVPPVPAPPPSLSSTASAGPAAAAVPTPAPASIPFTSSSATFQRTVQSNFQHVLVYEDPELQQKALECIPHELLRSRAKERLKQANDADAACSLGEE-----DMLVLDLLQWFKSDFFSWVDNLPCIQCGG---KTQPSG-SLSPSSDDLHWDAGRVENHFCHTCQLSTRFPRYNNPEKLLETRKGRCGEWANCFTLLCRALGLEARYIWDSTDHVWTEVYSQSQRRWIHCDPCENACDKPLLYEVGWGKKLSYILAFSKDQVADVTWRYSCKHPEVLSRRTQVQETWLLHMLNKLNAERQQFLGAERKQQLLQRLLVELVEFISPKSPQPGELGGRMSGSLAWRAARGETGASNAKEDTQENVFTPSESEKESKRFHICYNVTKDCYYRVSNGQ------ETIQGWQKGAWRTENMFRKEEHDWQMVYLARTEGASFGRMSWKFNCAPAGMKMKSASVRVFSQTFHSGTVRWSLSTNETTTEFPGDGELHSFSNVSGGTELIVEAELTGGDGSTSWQHAQLFRQSLKDTEKVLFEVMVEMEKS", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q7KRR5-1", "uniprot_id": "NGLY1_DROME", "id": "Q7KRR5-1", "name": "Peptide-N(4)-(N-acetyl-beta-glucosaminyl)asparagine amidase", "aln": "MVDINLECVHQIEPKTRSAGQQQQERGLKEAYLEAVRILLVLLENILAQPENSMFRTIRQENKAIKEKLLSLPGCERLLEAIGFVRAPSSNAYTLPTEVSLQQVKKYRDALSERRTAWLNGT---------------VSKSPPQQSTTSTTPLFIKPSVEYRHRIAFPRVLRTNNNFLQSLELYSDAVMQYEDNLLLATGRTLIPVEELTEMASEKLIDIQDQIASGERQEKEPCVRDLLLVELVNWFNTQFFQWVNNIPCRVCGS---EESRLRRTEREGD---------IRVEVTVCCGQESKFYRYNDISQLLVSRKGRCGEYANCFTFLCRALDYDARIVHSHFDHVWTEVYSEAQMRWLHVDPSENVIDSPLMYQHGWKRHIDYILAYSRDDIQDVTWRYTNDHQKILHLRKLCGEKEMVQTLDAIRAKRRQNCTADRKLFLSQRNMYEVIGLTLERKPTENELKGRSSGSLSWRQSRGEHTFT------NIFVFNLSATELQKRQLNVRYSCATDTYERYAKEGEHITILDSYKTWQKAQFSSKNIFRKVERDWKMAYLARLEDTDCGEIAWTFDFSKTNLKVKSYNLVFETKTFGDGKISVTVDATDGSASVEN------------ATGFKIVAKLTGGKGDVAWQHTQLFRQSLN-SRDYPFDLQVQLH--", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q02890-1", "uniprot_id": "PNG1_YEAST", "id": "Q02890-1", "name": "Peptide-N(4)-(N-acetyl-beta-glucosaminyl)asparagine amidase", "aln": "--------------------MGEVYEKNNIDFDSIAKMLLIKYKDFILS--------------------------------------------KFKKAAPVENIR-------------------------------------------------------------FQNLVHTNQFAQGVLGQSQHLCTVYDNPSWHSIVLETLDLDLIYKNVDKEFAKDGHAEGENIYTDY-------LVKELLRYFKQDFFKWCNKPDCNHCGQNTSENMTPLGSQGPNGEESKFNCGTVEIYKCNRCGNITRFPRYNDPIKLLETRKGRCGEWCNLFTLILKSFGLDVRYVWNREDHVWCEYFSNFLNRWVHVDSCEQSFDQPYIYSINWNKKMSYCIAFGKDGVVDVSKRYILQN---ELPRDQIKEEDLKFLCQFITKRLRYSLNDDEIYQLACRDEQEQIELIRGKTQETKSESVSAASKSSNR-----------------------------------------------------------------------------------------GRESGSADWKAQRGEDGK--------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . : . ::*: .::: . : ..::::: . : . *:: : . : .:.: . : *: :*:.:*: :** * :: * ** : : .. :. * .:* ***: :** :* *****:.* **: ::.. :.* : . **** * :* **:* *..*: *.* :*. .* :::.* :*:.:* : **: ** .: * * : : : . : .. * * * : : :. . :.. : * . . . *. : . . ", "identical_positions": 57, "similar_positions": 108, "identity": "8.39%" }, { "cls_id": "homologset.agr.MGI:1913277", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q56AP7-1", "uniprot_id": "CRBN_RAT", "id": "Q56AP7-1", "name": "Protein cereblon", "aln": "------------------------------------------------------------MAGEGDHQDAAHNMGNHLPLLPADSEDEDDEIEMEVEDQDSKE----------------------------------------------------------------------------------ARKPNIINFDTSLPTSHTYLGADMEEFHGRTLHDDDSCQVIPVLPEVMMILIPGQTLPLQLSH---PQEVSMVRNLIQKDRTFAVLAYS---NVQEREAQFGTTAEIYAYREEQEFGIEVVKVKAIGRQRFKVLELRTQSDGIQQ-------AKVQILPECVLPSTMSAVQLESLNKCQIFPSKPISWEDQYSCKWWQKYQKRKFHCANLTSWPRWLYSLYDAETLMDRIKKQLREWDENLKEDSLPANPIDFSYRVAACLPIDDVLRIQLLKIGSAIQRLRCELDIMNKCTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKASN--LNLIGRPSTVHSWFPGYAWTIAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTIPETEDEISPDKVILCL----------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8C7D2-1", "uniprot_id": "CRBN_MOUSE", "id": "Q8C7D2-1", "name": "Protein cereblon", "aln": "------------------------------------------------------------MAGEGDQQDAAHNMGNHLPLLPADSEDEDDEIEMEVEDQDSKE----------------------------------------------------------------------------------ARKPNIINFDTSLPTSHTYLGADMEEFHGRTLHDDDSCQVIPVLPEVLMILIPGQTLPLQLSH---PQEVSMVRNLIQKDRTFAVLAYS---NVQEREAQFGTTAEIYAYREEQEFGIEVVKVKAIGRQRFKVLELRTQSDGIQQ-------AKVQILPECVLPSTMSAVQLESLNKCQVFPSKPISWEDQYSCKWWQKYQKRKFHCANLTSWPRWLYSLYDAETLMDRIKKQLREWDENLKDDSLPENPIDFSYRVAACLPIDDVLRIQLLKIGSAIQRLRCELDIMNKCTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKASN--LNLIGRPSTVHSWFPGYAWTIAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTIPETEDEISPDKVILCL----------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q96SW2-1", "uniprot_id": "CRBN_HUMAN", "id": "Q96SW2-1", "name": "Protein cereblon", "aln": "------------------------------------------------------------MAGEGDQQDAAHNMGNHLPLLPAESEEED---EMEVEDQDSKE----------------------------------------------------------------------------------AKKPNIINFDTSLPTSHTYLGADMEEFHGRTLHDDDSCQVIPVLPQVMMILIPGQTLPLQLFH---PQEVSMVRNLIQKDRTFAVLAYS---NVQEREAQFGTTAEIYAYREEQDFGIEIVKVKAIGRQRFKVLELRTQSDGIQQ-------AKVQILPECVLPSTMSAVQLESLNKCQIFPSKPVSREDQCSYKWWQKYQKRKFHCANLTSWPRWLYSLYDAETLMDRIKKQLREWDENLKDDSLPSNPIDFSYRVAACLPIDDVLRIQLLKIGSAIQRLRCELDIMNKCTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACN--LNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTIPDTEDEISPDKVILCL----------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q68EH9-1", "uniprot_id": "CRBN_DANRE", "id": "Q68EH9-1", "name": "Protein cereblon", "aln": "-------------------------------------------------------------------------MGNQLQLLPENEEEEED--DMETEDRDGED----------------------------------------------------------------------------------VEKPSIINFDTSLPTSHAYLGSDMEEFHGRTLHDEDSVQNLPVLPHVALILIPGQTLPLQLFR---PQEVSMFRNLVSQDRTFAVLAHSPDPSGTETKAEFGTTAEIYAFREEQEYGIETVKIKAVGRQRFRVHDIRTQADGIRQ-------AKVQILPERILPDPLCALQFLPR-LHTHSPQTKHTQTTPPQKRCSQNYRQKKLHCASMTSWPPWVYSLYDSKTLMSRVKKQLHEWDENLKDESLPTNPTDFSYRVAACLPIDDALRLQLLKIGSAIQRLRCELDIMDRCTSLCCKQCQDTEITSKNEIFSLSLYGPMAAYVNPHGYVHETLTVYKASN--LNLIGRPSTLHSWFPGYAWTIAQCRTCSSHMGWKFSAVKKDLSPPRFWGLTRSALLPTIPQGEEGVE-GSRLLCL----------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VH36-1", "uniprot_id": "CRBN_DROME", "id": "Q9VH36-1", "name": "Protein cereblon", "aln": "MDEEENSEINSVQARDEDVQLEDQQSQGLQDRQVDVIEQAWNNAMPDEPSPPAEDAFQDPLATDGEGGDALEAMVENVLQDDTASEGSHPSSDMSLESPGSEDDSDLESLPHWMIPQNRLRSAVDMMVSQARNRDGGIAALLSGDNFLQRVRSMVFSQERRRSRTSEETSQEAAEQPVDPPPQQPPRPPIDIGFDTNLPAEHSYFGNHLSRVPGVDYLEVGSVHHMLIFLH-QHILFPGEVLPFMIDGRMFDEDMPGLDGLIFG-VSFPRLQPP----EDNPHKLYGVTCQIYE-RGESGRGLVFYKSRALQRIVINCDDIKGSPQYIARNPTSKCFSKVKILPEYFLPEPLQTVDMGSMARFRDIPS------------MRDKYRR---FQLSTTTWPSDACQEYSFSSIVERARQRL----ESQKIDTMPKCPIQLSFWLVRNLHLTEKMMRLTFLTDSVNTRLQLIKSTFKDETLFFCRYCNS-SLALCSDLFAMSKHGVQTQYCNPEGYIHETNTVYRVISHAIGYSGEPSTKFSWFPGYQWHIILCKFCAQHVGWEFKAVHPNLTPKVFFGLAGSSVRIGKASEYSPFNGTTYVVRNMMRMISSDME", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * ::: .* .. :*. *. ..:: . * *.***.**:.*:*:* .:... * : .* : : :: . **:**:.**: : :::. . .*: :*. * . : . :*.*.:** * *. *: * :*: * :. ::: ..: * : :**:**** .**..: :::: . *. ::*:: . . *:** . *. .:::.* :::* *. * :::* * ::*: :. * : : : : .*. **: . :. * : *: *:. .:: .::*::* * : * **.**:*** ***:. . :. *.*** .****** * : *: *:.*:**:*.*.: :::* *:**: *:: .. . .. . :: ", "identical_positions": 101, "similar_positions": 160, "identity": "16.5%" }, { "cls_id": "homologset.agr.MGI:1913283", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9QZK9-1", "uniprot_id": "DNS2B_RAT", "id": "Q9QZK9-1", "name": "Deoxyribonuclease-2-beta", "aln": "----MTAQPLKAALPLLFVALSGVLGTPVISCINEDGKAVDWFAFYKLPRRTSR---GGTGMGLDYLYLDST-MRTWSKSHHLINSSRSSLGRTLEQLYEAHNAK-NDTAYLIYNDAVPASVNYSGNYGHAKGLLVWNRVQGFWLIHSIPKFPPVPEKGYEYPSSGRQYAQSGLCITLKYSQYETIDSQLLVFQPNIYSCFIPNIFRWE--LIHMPQMCAKSSASKIPSRRLTVLQSAQGLNFLHFAKSTFYTDDIFAAWIAQKLKVHLLVESWQRKNHELPSNCSLPYHVYNIKAIRGP-LQSDFPSHHDHSKWCVSTKD---------SQARWTCIGDLNRSPHQALRSGGFICSKNRYIYQSFDRLVSHYASCN---", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9QY48-1", "uniprot_id": "DNS2B_MOUSE", "id": "Q9QY48-1", "name": "Deoxyribonuclease-2-beta", "aln": "----MTAKPLRTVLSLLFFALSGVLGTPEISCRNEYGEAVDWFIFYKLPKRTSK---ASEEAGLQYLYLDST-RQTWNKSLYLINSTRSALGRTLQHLYDTHNST-NDTAYLIYNDGVPGSVNYSRQYGHAKGLLVWNRTQGFWLIHSVPKFPPVH--GYEYPTSGRRYGQTGICITFGYSQFEEIDFQLLVLQPNIYSCFIPSTFHWK--LIYMPRMCANSSSLKIPVRYLAELHSAQGLNFVHFAKSSFYTDDIFTGWIAQKLKTHLLAQTWQKKKQELPSNCSLPYHVYNIKSIGVT-SKSYFSSRQDHSKWCVSIKG---------SANRWTCIGDLNRSLHQALRGGGFICTKNHYIYQAFHKLYLRYGFCK---", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8WZ79-1", "uniprot_id": "DNS2B_HUMAN", "id": "Q8WZ79-1", "name": "Deoxyribonuclease-2-beta", "aln": "MKQKMMARLLRTSFALLFLGLFGVLGAATISCRNEEGKAVDWFTFYKLPKRQNK---ESGETGLEYLYLDST-TRSWRKSEQLMNDTKSVLGRTLQQLYEAYASKSNNTAYLIYNDGVPKPVNYSRKYGHTKGLLLWNRVQGFWLIHSIPQFPPIPEEGYDYPPTGRRNGQSGICITFKYNQYEAIDSQLLVCNPNVYSCSIPATFHQE--LIHMPQLCTRASSSEIPGRLLTTLQSAQGQKFLHFAKSDSFLDDIFAAWMAQRLKTHLLTETWQRKRQELPSNCSLPYHVYNIKAIKLS-RHSYFSSYQDHAKWCISQKG---------TKNRWTCIGDLNRSPHQAFRSGGFICTQNWQIYQAFQGLVLYYESCK---", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0ACD6B683-1", "uniprot_id": "A0ACD6B683_DANRE", "id": "A0ACD6B683-1", "name": "deoxyribonuclease II", "aln": "----MFMLFQLSACCLLFLMG---FSEAVISCLNEDGQPVDWFIMYKLPIYKME---VKG-SGVDYMYLDPS-IMDFQISKYTVNSSTGALGRTLTQLYSGYTSN--SSVYMLYNDAPP-ELKYPSKYGHTKGVLMFDQDQGFWLTHSVPHFPPFPERNYSYPLTGKYYGQTLLCITFNYTQFPHISWQLAYLNPRVYNCSVPVAFRPD--IGEMAQICDGKTPAIKNRRSLQKLQSVQGQTFFSFAKSQNYVDDIYTGWVAQALGTDLLVESWLHQAHQLPSNCSLPWHVMNINAVCLP-GPQMFRSYEDHSKWCVSYT----------FKDQWTCLGDLNRDGGQAGRGGGLTCCQNSVIYKAFRKAMASYKHC----", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VED8-1", "uniprot_id": "Q9VED8_DROME", "id": "Q9VED8-1", "name": "", "aln": "----MRSLCFVLLFVWFFYQN---EAKSKVSCKDEAGNDVDWWHLYKLPKHYQHNDLGKDTSGLKYLYVTSQNYDTWQMSGKFISDPLSLPAQTLNPLNDDPSHT----LLAAYNDQQPNGTVFS-SGGHAKGVVASDGETAIWIVHSVPKFPTIP--DYSYPTSGEQYAQSMLCVTLKGEDLEKVGQILVYNEPHFYYQRNPLATRSDELFPSLERALHGQWRTESPFQKDLEVRSLDGKKFRLFGKSGRANVELYADVVAPTLDVSLFVEAWRDGAGNLPNSCDKSDKVLNVESISNPELSVDFKTTQDHSKWAVSRPTGILIYHWRVGGGDWICVGDINRQEGQLHRGGGTVCHKSARVSNLYRQLVTNYDKCAQQE", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * :* . . :** :* *: ***: :**** . *:.*:*: . : * :... . .:** * . . *** * :. . **:**:: : .:*: **:*:**.. .*.** :*. .*: :*:*: : :. * :*..* * : . : : : : ::* :* .* *.** :::: :* * . *:.::* :**..*. . :* *:::: . * : .**:**.:* * *:**:**. * *.** * :. : : : * * ", "identical_positions": 79, "similar_positions": 99, "identity": "20.79%" }, { "cls_id": "homologset.agr.MGI:1913284", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O00487-1", "uniprot_id": "PSDE_HUMAN", "id": "O00487-1", "name": "Ubiquitin C-terminal hydrolase PSMD14", "aln": "MDRLLRLGGGMPGLGQGPPTDAPAVDTAEQVYISSLALLKMLKHGRAGVPMEVMGLMLGEFVDDYTVRVIDVFAMPQSGTGVSVEAVDPVFQAKMLDMLKQTGRPEMVVGWYHSHPGFGCWLSGVDINTQQSFEALSERAVAVVVDPIQSVKGKVVIDAFRLINANMMVLGHEPRQTTSNLGHLNKPSIQALIHGLNRHYYSITINYRKNELEQKMLLNLHKKSWMEGLTLQDYSEHCKHNESVVKEMLELAKNYNKAVEEEDKMTPEQLAIKNVGKQDPKRHLEEHVDVLMTSNIVQCLAAMLDTVVFK", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "O35593-1", "uniprot_id": "PSDE_MOUSE", "id": "O35593-1", "name": "Ubiquitin C-terminal hydrolase PSMD14", "aln": "MDRLLRLGGGMPGLGQGPPTDAPAVDTAEQVYISSLALLKMLKHGRAGVPMEVMGLMLGEFVDDYTVRVIDVFAMPQSGTGVSVEAVDPVFQAKMLDMLKQTGRPEMVVGWYHSHPGFGCWLSGVDINTQQSFEALSERAVAVVVDPIQSVKGKVVIDAFRLINANMMVLGHEPRQTTSNLGHLNKPSIQALIHGLNRHYYSITINYRKNELEQKMLLNLHKKSWMEGLTLQDYSEHCKHNESVVKEMLELAKNYNKAVEEEDKMTPEQLAIKNVGKQDPKRHLEEHVDVLMTSNIVQCLAAMLDTVVFK", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A0G2JZJ1-1", "uniprot_id": "A0A0G2JZJ1_RAT", "id": "A0A0G2JZJ1-1", "name": "Ubiquitin C-terminal hydrolase PSMD14", "aln": "MDRLLRLGGGMPGLGQGPPTDAPAVDTAEQVYISSLALLKMLKHGRAGVPMEVMGLMLGEFVDDYTVRVIDVFAMPQSGTGVSVEAVDPVFQAKMLDMLKQTGRPEMVVGWYHSHPGFGCWLSGVDINTQQSFEALSERAVAVVVDPIQSVKGKVVIDAFRLINANMMVLGHEPRQTTSNLGHLNKPSIQALIHGLNRHYYSITINYRKNELEQKMLLNLHKKSWMEGLTLQDYSEHCKHNESVVKEMLELAKNYNKAVEEEDKMTPEQLAIKNVGKQDPKRHLEEHVDVLMTSNIVQCLAAMLDTVVFK", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9V3H2-1", "uniprot_id": "PSDE_DROME", "id": "Q9V3H2-1", "name": "26S proteasome non-ATPase regulatory subunit 14", "aln": "MDRLLRLGGAMP--QAAPPTDAPVVDTAEQVYISSLALLKMLKHGRAGVPMEVMGLMLGEFVDDYTVQVIDVFAMPQTGTGVSVEAVDPVFQAKMLDMLKQTGRPEMVVGWYHSHPGFGCWLSGVDINTQQSFEALSERAVAVVVDPIQSVKGKVVIDAFRLINPNMLVLGQEPRQTTSNLGHLQKPSVQALIHGLNRHYYSISINYRKNELEQKMLLNLHKKSWKDGLTLSDYNEHCSINEDTVAEMLDLAKNYNKSLEDEEKMTPEQLAIKNVGKQDPKRHLEEKVDKVMQNNIVQCLGAMLDTIVFK", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P43588-1", "uniprot_id": "RPN11_YEAST", "id": "P43588-1", "name": "Ubiquitin C-terminal hydrolase RPN11", "aln": "MERLQRL--MMN--SKVGSADTGRDDTKETVYISSIALLKMLKHGRAGVPMEVMGLMLGEFVDDYTVNVVDVFAMPQSGTGVSVEAVDDVFQAKMMDMLKQTGRDQMVVGWYHSHPGFGCWLSSVDVNTQKSFEQLNSRAVAVVVDPIQSVKGKVVIDAFRLIDTGALINNLEPRQTTSNTGLLNKANIQALIHGLNRHYYSLNIDYHKTAKETKMLMNLHKEQWQSGLKMYDYEEKEESNLAATKSMVKIAEQYSKRIEEEKELTEEELKTRYVGRQDPKKHLSETADETLENNIVSVLTAGVNSVAIK", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*:** ** * .:*: ** * *****:*******************************.*:*******:********** ******:******** :*****************.**:***:*** *..*************************:.. :: . ******** * *:*..:*************:.*:*:*. * ***:****:.* .**.: **.*: . * .. .*:.:*::*.* :*:*.::* *:* : **:****:**.* .* : .***. * * ::::.:*", "identical_positions": 196, "similar_positions": 68, "identity": "63.23%" }, { "cls_id": "homologset.agr.MGI:1913287", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9JL99-1", "uniprot_id": "CLC1B_MOUSE", "id": "Q9JL99-1", "name": "C-type lectin domain family 1 member B", "aln": "---MQDEDGYITLNIKPRKQALSSA-----------EPASSWWRVMALVLLISS-------------MGLVVGLVALGIMSVTQQKYLLAEKENLSATLQQLAKKFCQELIRQSEIKTKSTFEHKCSPCATKWRYHGDSCYGFFRRNLTWEESKQYCTEQNATLVKTASQSTLDYIAERITSVR--WIGLSRQNSK-KDWMWEDSSVLRKNGINLSGNTEEN--MNCAYLHNG----KIHPASCKERHYLICERNAGMTRVDQLL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8I6GBW7-1", "uniprot_id": "A0A8I6GBW7_RAT", "id": "A0A8I6GBW7-1", "name": "", "aln": "---MQDEDGYITLNIKPRKQALSS--------------------------------------------------------AVTQQKYLLAEKENLSATLQQLAKKFCQELIRQSEIKTKSSFEHKCSPCATKWRYHGDSCYGFFRRNLTWEDSKLFCSEQNATLVKTASQSTLKYITDRITSVR--WIGLSRQNSK-KDWMWEDSSVLHNNSIDLSRNTEEN--MNCAYLHNG----KIHPASCTERHYLICERNAALTRVEQLL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9P126-1", "uniprot_id": "CLC1B_HUMAN", "id": "Q9P126-1", "name": "C-type lectin domain family 1 member B", "aln": "---MQDEDGYITLNIKTRKPALISVG----------SASSSWWRVMALILLILC-------------VGMVVGLVALGIWSVMQRNYLQGENENRTGTLQQLAKRFCQYVVKQSELKG-TFKGHKCSPCDTNWRYYGDSCYGFFRHNLTWEESKQYCTDMNATLLKIDNRNIVEYIKARTHLIR--WVGLSRQKSN-EVWKWEDGSVISENMFEFLEDGKGN--MNCAYFHNG----KMHPTFCENKHYLMCERKAGMTKVDQLP", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A1Z8L7-1", "uniprot_id": "A1Z8L7_DROME", "id": "A1Z8L7-1", "name": "C-type lectin domain-containing protein", "aln": "---MQKSIIFLVLPLCLSSSYSAACEGV------ESDSQCAAYCYGVLNPCIAS-------------MGNLQRRVEACEAAVAIARIALNDRR-LDNFGTSTNLQLENQNTSQQLLTHGTAMGRKLEENEIFQQLGSKYYYIEKEEKLNWHDALDKCHKMGGHLASLQSQEELDRFNNQLNGLNRYWIDVTNQFNE-SEFVSVTKGSKANFLSWADGEPTKD--GECVDIRTFNGKTTMNDNSCFANLYFICEKSIEI-------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VPS1-1", "uniprot_id": "Q9VPS1_DROME", "id": "Q9VPS1-1", "name": "", "aln": "MFKYDTYFLYLIVLLDPQGAQENNCPKVSLSERLEKRGEFSLVEFDPLLKFIVKNPHKELLGEIEGLVGHTENKLQPMKSVIPNQSKALLNYLDLHSKLEYLDAALQKAINSLQCSLKNTKVMSTGKPHPEFQKLGSRYFYIERHVRQNWFDAADKCRRMGGHLATPQDEDELYLIRKQLEARW-FWLDISNLVDK-DQYISLATGKEVSYLKWRHGEPKKSSTANCAYLYAG----DYYTYQCSDRNFFICQAV----------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VLM0-1", "uniprot_id": "Q9VLM0_DROME", "id": "Q9VLM0-1", "name": "", "aln": "MYKYATCIFSIFALWNFWGVSAKKQD---------TSTGTNELPKAPMPYYTIEN------IDMHQQHWFTYNSLRQNGTLWRIGNMEQRLEMRLQSFQNQMETKLRALKQQIEPYMENVKMSNKIKMS-VFKKIGSRHFYLEKQKKMPWDSAYDTCRQMGGHLANILDEKELNEIFSEETKKK-YWVDINSRANDGASWISTLSGRDVPFLKWKPNLATNIH-NHCVYINSN----EMYFENCANDNYFACQAEQWA-------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : . . . : . * . . * .: * .. * . ... : : . *:.:. .. : . .*. : * :: *: ", "identical_positions": 8, "similar_positions": 34, "identity": "3.02%" }, { "cls_id": "homologset.agr.MGI:1913288", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q6TUF2-1", "uniprot_id": "SDHF3_RAT", "id": "Q6TUF2-1", "name": "Succinate dehydrogenase assembly factor 3, mitochondrial", "aln": "-------------MTG-RHVSRVRSLYRRILQLHRALPPDLKALGDQYVKDEFRRHKTVG-PGEAQRFLKEWETYAAVLWQQAKDSRQSSSGKACFGTSLPEEKLNDFRDEQIGQLQELMQEATKPNRQFSITESTKPHL----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8BQU3-1", "uniprot_id": "SDHF3_MOUSE", "id": "Q8BQU3-1", "name": "Succinate dehydrogenase assembly factor 3, mitochondrial", "aln": "-------------MPG-KHVSRVRALYRRILLLHRALPPDLKALGDQYVKDEFRRHKTVG-PGEAQRFLKEWETYAAVLWQQAEDSRQSSTGKACFGTSLPEEKLNDFRDEQIGQLQELMQEATKPNRQFSITESTKPQL----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9NRP4-1", "uniprot_id": "SDHF3_HUMAN", "id": "Q9NRP4-1", "name": "Succinate dehydrogenase assembly factor 3, mitochondrial", "aln": "-------------MPG-RHVSRVRALYKRVLQLHRVLPPDLKSLGDQYVKDEFRRHKTVG-SDEAQRFLQEWEVYATALLQQANENRQNSTGKACFGTFLPEEKLNDFRDEQIGQLQELMQEATKPNRQFSISESMKPKF----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q5XIY4-1", "uniprot_id": "SDHF3_DANRE", "id": "Q5XIY4-1", "name": "Succinate dehydrogenase assembly factor 3, mitochondrial", "aln": "-------------MANPAHISAVRTLYKKILVLHRFLPIDLRALGDQYVKDEFRRHKTSS-DEEAKHFMVEWQNYKDTLQTQVLEAMGNK--KLVFGADLSEDKLKHFQDEQIGQLYELMLESTKPNRQFDIQEEGTPK-----", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q8SZ16-1", "uniprot_id": "SDHF3_DROME", "id": "Q8SZ16-1", "name": "Succinate dehydrogenase assembly factor 3, mitochondrial", "aln": "--------MSRILMSQLTHPQRVRLLYKTILRLHRGLPAELRALGDNYVRDEFRRHLKCN-PMEAQLFMTEWARYASTITQQLG-IRGKP--KGELGEEIDPKTVEMLKDDQVVQLYELMLAAKG-------VEDAQGK-----", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q04401-1", "uniprot_id": "SDHF3_YEAST", "id": "Q04401-1", "name": "Succinate dehydrogenase assembly factor 3, mitochondrial", "aln": "MNNKLIYRSVRFATHNSQLLLPPLVLYRRILRQHKLLPGPQREMGDQYVRNEFKLHKDIDNPLHIVGFLASWQDYLHMIS-----------NGKWKDATLSSETLEKLSPEQTVQLYELMKETQKLHQDNEIESSKDVKRNNKD", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " **: :* *: ** : :**:**::**: * . . *: .* * : . : ..:: : :* ** *** : .. : ", "identical_positions": 22, "similar_positions": 26, "identity": "15.28%" }, { "cls_id": "homologset.agr.MGI:1913290", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZA85-1", "uniprot_id": "D3ZA85_RAT", "id": "D3ZA85-1", "name": "NFU1 iron-sulfur cluster scaffold homolog, mitochondrial", "aln": "-----MAAAERAWG-----AAVGVARLCRRLCHVAT--PHAFK---KQPLHQYVQRPLFPLRTPLYNTVRFMFIQTQDTPNPNSLKFIPGK-PVLETR-TMDFPTPAAAF----RSPLARQLFR-IEGVKSVFFGPDFITVTKENEELDWNLLKPDIYATIMDFFASGLPLVTEETPP--GEAGSS------------EEDDEVVAMIKELLDTRIRPTVQEDGGDVIYRGFED--GIVRLKLQGSCTSCPSSIITLKSGIQNMLQFYIPEVEGVEQVMDDEESDEKEANSP-------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9QZ23-1", "uniprot_id": "NFU1_MOUSE", "id": "Q9QZ23-1", "name": "NFU1 iron-sulfur cluster scaffold homolog, mitochondrial", "aln": "-----MAAAERAWG-----AAVGVVRLCRRFCHVAT--PHTFK---KQPLHQYVRRPLFPLRAPLCNTVRFMFIQTQDTPNPNSLKFIPGK-PVLETR-TMDFPTPAAAF----RSPLARQLFR-IEGVKSVFFGPDFITVTKENEELDWNLLKPDIYATIMDFFASGLPLVTEETPPPPGEAGS-------------EEDDEVVAMIKELLDTRIRPTVQEDGGDVIYRGFED--GIVRLKLQGSCTSCPSSIITLKSGIQNMLQFYIPEVEGVEQVMDDDESDEKEANSS-------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9UMS0-1", "uniprot_id": "NFU1_HUMAN", "id": "Q9UMS0-1", "name": "NFU1 iron-sulfur cluster scaffold homolog, mitochondrial", "aln": "----MAATARRGWG-----AAAVAAGLRRRFCHMLKN-PYTIK---KQPLHQFVQRPLFPLPAAFYHPVRYMFIQTQDTPNPNSLKFIPGK-PVLETR-TMDFPTPAAAF----RSPLARQLFR-IEGVKSVFFGPDFITVTKENEELDWNLLKPDIYATIMDFFASGLPLVTEETPS--GEAGS-------------EEDDEVVAMIKELLDTRIRPTVQEDGGDVIYKGFED--GIVQLKLQGSCTSCPSSIITLKNGIQNMLQFYIPEVEGVEQVMDD-ESDEKEANSP-------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AC58G6J7-1", "uniprot_id": "A0AC58G6J7_DANRE", "id": "A0AC58G6J7-1", "name": "NFU1 iron-sulfur cluster scaffold homolog, mitochondrial", "aln": "--MPIQDVTSRSLGALTSMAAYRSVGFGRNLAAVLKR-TYHGSGLIRPPVYTMGRSPVPQQTTTVF--IRNMFIQTQDTPNPNSLKFLPGR-AVLDSG-TMDFAGPRDAF----CSPLARQLFR-IDGVKSVFFGPDFITITKTSGETEWKVIKPDVFATIMDFFTSGLPVINEADAPRADTAPS-------------EDDDEVVAMIKELLDTRIRPTVQEDGGDVLYHGFED--GIVKLKLQGSCTSCPSSIITLKNGIQNMLQFYVPEVEGVEQVKEE---DVEVA----------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q8SY96-1", "uniprot_id": "NFU1_DROME", "id": "Q8SY96-1", "name": "NFU1 iron-sulfur cluster scaffold homolog, mitochondrial", "aln": "MSKFLSQAALNTLRN----TRLGSRQLVRSFKGISNTRNHRIPAHQESGCGHSVGCGLLELRMPVAC-RRSMFIQTQDTPNPESLKFLPGV-DVLGKGNTYDFPNGTTAH----NSPLAKLLFR-VEGVKGVFFGADFVTISKQEG-AEWSLIKPEVFAVIMDFFASGLPVLNDAQPN--ADTEIL------------EDDDETVMMIKELLDTRIRPTVQEDGGDIVFMGYEG--GVVKLKMQGSCSSCPSSIVTLKNGVQNMLQFYIPEVESVEQVFDEADRMIESEFERFEKNLKTLKQQEPSGGGPH", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "B8A6A3-1", "uniprot_id": "B8A6A3_DANRE", "id": "B8A6A3-1", "name": "NFU1 iron-sulfur cluster scaffold homolog, mitochondrial", "aln": "------MAASIRWS---------LQRFVR-----SNHLRYPVNDRNQCYSLWAARRIQHQQNEFKSFSVRKLSILTQDTPNPRSLKFLPGK-PVLGTG-TQDFPTSASAE----SSPLARDLFQ-ISGIKSVFYGPDFITLTKTDDDVEWTDIKRHAIEVISKFFEGGEAITTGAAHA---ESSVT------------EDDDEIVSLIKELLDTRIRPTVQEDGGDVIFKGFED--GTVKLKLVGSCTGCPSSTVTLKNGIQNMMQFYIPEVDNVEQVQDEVDEINMKVYTELEKKLQDV-----------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P32860-1", "uniprot_id": "NFU1_YEAST", "id": "P32860-1", "name": "NifU-like protein, mitochondrial", "aln": "--------------------------------------------------MFKSVAKLGKSPIFYLNSQRLIHIKTLTTPNENALKFLSTDGEMLQTRGSKSIVIKNTDENLINHSKLAQQIFLQCPGVESLMIGDDFLTIN-KDRMVHWNSIKPEIIDLLTKQLAYGEDVISKEFHAVQEEEGEGGYKINMPKFELTEEDEEVSELIEELIDTRIRPAILEDGGDIDYRGWDPKTGTVYLRLQGACTSCSSSEVTLKYGIESMLKHYVDEVKEVIQIMDPEQEIALKEFDKLEKKLESSKNTSHEK----", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * : * * *** .:***:. :* . : .: * **: :* *::.:: * **:*:. . .*. :* . : . : * : . *:*:* :*:**:******:: *****: : *:: * * *:: *:*:.*.** :*** *::.*::.*: **. * *: : ", "identical_positions": 58, "similar_positions": 58, "identity": "18.65%" }, { "cls_id": "homologset.agr.MGI:1913292", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q642G2-1", "uniprot_id": "SOSD1_RAT", "id": "Q642G2-1", "name": "Sclerostin domain-containing protein 1", "aln": "MLPPAIHLSLIPLLCILMKNCLAFKNDATEILYSHVVKPVSAHPSSNSTLNQARNGGRHFSSTGLDRNSRVQVGCRELRSTKYISDGQCTSISPLKELVCAGECLPLPVLPNWIGGGYGTKYWSRRSSQEWRCVNDKTRTQRIQLQCQDGSTRTYKITVVTACKCKRYTRQHNESSHNFESVSPAKPAQHHRERKRASKSSKHSLS----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9CQN4-1", "uniprot_id": "SOSD1_MOUSE", "id": "Q9CQN4-1", "name": "Sclerostin domain-containing protein 1", "aln": "MLPPAIHLSLIPLLCILMRNCLAFKNDATEILYSHVVKPVPAHPSSNSTLNQARNGGRHFSSTGLDRNSRVQVGCRELRSTKYISDGQCTSISPLKELVCAGECLPLPVLPNWIGGGYGTKYWSRRSSQEWRCVNDKTRTQRIQLQCQDGSTRTYKITVVTACKCKRYTRQHNESSHNFESVSPAKPAQHHRERKRASKSSKHSLS----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6X4U4-1", "uniprot_id": "SOSD1_HUMAN", "id": "Q6X4U4-1", "name": "Sclerostin domain-containing protein 1", "aln": "MLPPAIHFYLLPLACILMKSCLAFKNDATEILYSHVVKPVPAHPSSNSTLNQARNGGRHFSNTGLDRNTRVQVGCRELRSTKYISDGQCTSISPLKELVCAGECLPLPVLPNWIGGGYGTKYWSRRSSQEWRCVNDKTRTQRIQLQCQDGSTRTYKITVVTACKCKRYTRQHNESSHNFESMSPAKPVQHHRERKRASKSSKHSMS----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q1LUC2-1", "uniprot_id": "Q1LUC2_DANRE", "id": "Q1LUC2-1", "name": "", "aln": "MPLNTCEYQLLFLLCFLMKSCHAFKNDATEEFNGHALASAQETPN-NASLNRARNGGRRPESR--HQTEQHQVGCRELRSTKYISDGQCTSLNPVKELVCAGECLPTHLLPNWIGGGH---YWSRRDAQEWRCVTDRTRTQRIKLQCQDGTTRTYKITAVTSCTCKRYTRQNNESSHAPQSHSKDHPLQSPKKKKSKNKNSKLTSKKKEI", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* : . *: * *:**:.* ******** : .*.: .. *. *::**:******: .. .:. : ********************:.*:*********** :********: *****.:******.*:******:******:*******.**:*.*******:***** :* * :* * :::* .*.** : . ", "identical_positions": 120, "similar_positions": 47, "identity": "57.14%" }, { "cls_id": "homologset.agr.MGI:1913293", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P35434-1", "uniprot_id": "ATPD_RAT", "id": "P35434-1", "name": "ATP synthase F(1) complex subunit delta, mitochondrial", "aln": "MLPAALLRHPGLRRLVLQARTYAQAAASPAP-AAGPGQMSFTFASPTQVFFDGANVRQVDVPTLTGAFGILASHVPTLQVLRPGLVMVHAEDGTTTKYFVSSGSVTVNADSSVQLLAEEVVTLDMLDLGAARANLEKAQSELSGAADEAARAEIQIRIEANEALVKALE", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9D3D9-1", "uniprot_id": "ATPD_MOUSE", "id": "Q9D3D9-1", "name": "ATP synthase F(1) complex subunit delta, mitochondrial", "aln": "MLPASLLRHPGLRRLMLQARTYAEAAAAPAP-AAGPGQMSFTFASPTQVFFDSANVKQVDVPTLTGAFGILASHVPTLQVLRPGLVVVHTEDGTTTKYFVSSGSVTVNADSSVQLLAEEAVTLDMLDLGAARANLEKAQSELSGAADEAARAEIQIRIEANEALVKALE", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P30049-1", "uniprot_id": "ATPD_HUMAN", "id": "P30049-1", "name": "ATP synthase F(1) complex subunit delta, mitochondrial", "aln": "MLPAALLRRPGLGRLVRHARAYAEAAAAPAA-ASGPNQMSFTFASPTQVFFNGANVRQVDVPTLTGAFGILAAHVPTLQVLRPGLVVVHAEDGTTSKYFVSSGSIAVNADSSVQLLAEEAVTLDMLDLGAAKANLEKAQAELVGTADEATRAEIQIRIEANEALVKALE", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9W2X6-1", "uniprot_id": "Q9W2X6_DROME", "id": "Q9W2X6-1", "name": "ATP synthase F(1) complex subunit delta, mitochondrial", "aln": "------------MSFVKNARLLAARGARLAQNRSYSDEMKLTFAAANKTFYDAAVVRQIDVPSFSGSFGILAKHVPTLAVLKPGVVQVVENDGKTLKFFVSSGSVTVNEDSSVQVLAEEAHNIEDIDANEARQLLAKYQSQLSSAGDDKAKAQAAIAVEVAEALVKAAE", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q12165-1", "uniprot_id": "ATPD_YEAST", "id": "Q12165-1", "name": "ATP synthase subunit delta, mitochondrial", "aln": "MLRSIIGKSASRSLNFVAKRSYAEAAAASSG-------LKLQFALPHETLYSGSEVTQVNLPAKSGRIGVLANHVPTVEQLLPGVVEVME-GSNSKKFFISGGFATVQPDSQLCVTAIEAFPLESFSQENIKNLLAEAKKNVS-SSDAREAAEAAIQVEVLENLQSVLK", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . * * .* : :.: ** . :.::..: * *:::*: :* :*:** ****: * **:* * ...: *:*:*.* :*: **.: : * *. :: :. : * : : :: :.* *: * :*. * * .. :", "identical_positions": 37, "similar_positions": 53, "identity": "21.89%" }, { "cls_id": "homologset.agr.MGI:1913294", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9DD18-1", "uniprot_id": "DTD1_MOUSE", "id": "Q9DD18-1", "name": "D-aminoacyl-tRNA deacylase 1", "aln": "MKAVVQRVTRASVTVGGEQISAIGRGICVLLGISMEDSQKELEHMVRKILNLRVFEDESGKHWSKSVMDKEYEVLCVSQFTLQCVLK-GNKPDFHLAMPTEQAESFYNSFLEQLRKSYRPELIRDGKFGAYMQVHIQNDGPVTIELESPAPGAASSDPKQLSKLEKQQQRKEKTRAKGPSESSKERNAPR-KEDRSASSGAEGDVSSEREP", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8TEA8-1", "uniprot_id": "DTD1_HUMAN", "id": "Q8TEA8-1", "name": "D-aminoacyl-tRNA deacylase 1", "aln": "MKAVVQRVTRASVTVGGEQISAIGRGICVLLGISLEDTQKELEHMVRKILNLRVFEDESGKHWSKSVMDKQYEILCVSQFTLQCVLK-GNKPDFHLAMPTEQAEGFYNSFLEQLRKTYRPELIKDGKFGAYMQVHIQNDGPVTIELESPAPGTATSDPKQLSKLEKQQQRKEKTRAKGPSESSKERNTPR-KEDRSASSGAEGDVSSEREP", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8I6A4Q0-1", "uniprot_id": "A0A8I6A4Q0_RAT", "id": "A0A8I6A4Q0-1", "name": "D-aminoacyl-tRNA deacylase", "aln": "------MLLAQNVTLEIYQISAIGRGICVLLGISMEDTQKELEHMVRKILNLRVFEDESGKHWSKSVMDKEYEVLCVSQFTLQCVLK-GNKPDLHLAMPTEQAESFYNSFLEQLRKSYRPELIRDGKFGAYMQVHIQNDGPVTIELESPAPGAASSDPKQVTPTNNILKLTNKK--------STGKCKP----------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "F1QGC8-1", "uniprot_id": "DTD1_DANRE", "id": "F1QGC8-1", "name": "D-aminoacyl-tRNA deacylase 1", "aln": "MKAIIQRVTRASVTVGEEQISSIGRGLCVLLGISVEDTQKDVDYMVRKILNLRVFEDENGRAWSRSVMDGELEVLCVSQFTLQCLLK-GNKPDYHAAMPAELAQPFYNNMLEQLRETYKPELIKDGQFGAKMQVLIQNDGPVTIQLESPP---APTDPKLLSKQEKQQQRKEKTRSKGPSDSSREKAAQRSKVDPSASSGAEGDVSSEREP", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VGP0-1", "uniprot_id": "DTD_DROME", "id": "Q9VGP0-1", "name": "D-aminoacyl-tRNA deacylase", "aln": "MRAVIQRVKAAKVTVLDELVSSIGPGLCVLVGIKASDTAKDVEYLVRKILALRLFEEE-GKRWQKSVKDLNLELLCVSQFTLYHRLK-GNKPDFLAAMKGEEAQELYNQFLDRLGQSYDSTKIKDGKFGAYMQVHIENDGPVTINLESPE-------------QKDTDREVDK--------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q07648-1", "uniprot_id": "DTD_YEAST", "id": "Q07648-1", "name": "D-aminoacyl-tRNA deacylase", "aln": "MKIVLQKVSQASVVVDSKVISSIKHGYMLLVGISIDDSMAEIDKLSKKVLSLRIFEDESRNLWKKNIKEANGEILSVSQFTLMAKTKKGTKPDFHLAQKGHIAKELYEEFLKLLRSDLGEEKVKDGEFGAMMSCSLTNEGPVTIILDSDQ-------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : .*.: :*:* * :*:**. .*: ::: : :*:* **:**:* . *.:.: : : *:*.****** * *.*** * . *: :*:.:*. * . ::**:*** *. : *:***** *:* ", "identical_positions": 48, "similar_positions": 44, "identity": "22.75%" }, { "cls_id": "homologset.agr.MGI:1913296", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D4A565-1", "uniprot_id": "D4A565_RAT", "id": "D4A565-1", "name": "NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 5, mitochondrial", "aln": "MKLASTRRCPHSTWPSRHSPSLVDCPSRLPLPTLLPSVAVVAMAAMSLLQRASVAALTALSGRRAGTRLGVGSFLTRSFPKTVAPVRHSGDHGKRLFVIKPSLYYDARFLRLMKFYLLLTGIPVIIGITLVNIFIGEAELAEIPEGYIPEHWEYYKHPISRWIARTFYDGPEKNYEKTLAILQIESEKADLRLKELEVRRLMRARGDGPWYQYPTPEKEFIDYSPKSTPDN------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9CQH3-1", "uniprot_id": "NDUB5_MOUSE", "id": "Q9CQH3-1", "name": "NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 5, mitochondrial", "aln": "------------------------------------------MAAMSLLQRASVSALTALSCRRAGPRLGVGSFLTRSFPKTVAPVRHSGDHGKRLFVVKPSLYYDARFLRLMKFYLMLTGIPVIIGITLVNIFIGEAELAEIPEGYIPEHWEYYKHPISRWIARNFYDGPEKNYEKTLAILQIESEKAELRLKEQEVRRLMRARGDGPWYQFPTPEKEFIDHSPKATPDN------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O43674-1", "uniprot_id": "NDUB5_HUMAN", "id": "O43674-1", "name": "NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 5, mitochondrial", "aln": "------------------------------------------MAAMSLLRRVSVTAVAALSGRPLGTRLGFGGFLTRGFPKAAAPVRHSGDHGKRLFVIRPSRFYDRRFLKLLRFYIALTGIPVAIFITLVNVFIGQAELAEIPEGYVPEHWEYYKHPISRWIARNFYDSPEKIYERTMAVLQIEAEKAELRVKELEVRKLMHVRGDGPWYYYETIDKELIDHSPKATPDN------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VTU2-1", "uniprot_id": "Q9VTU2_DROME", "id": "Q9VTU2-1", "name": "NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 5, mitochondrial", "aln": "---------------------------------------------MVGWSRLLSPAAKFASYRAVLQEPACRNALHQQLR------RMGGDHGHHQMIIKPSRFQWDKFKDLLHFYVMLGVIPVTALVLYANIFVGPAQLAEIPEGYEPKHWEYEKHPISRFISRYILNSDQQNYEKSLHYLYEENEKAQIRLLEDEVRRKMSERNDYQAYYYRPSVAKYHRISKEAADELEALRGD", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * * .* * * . . . * : : * .****:: ::::** : :* *::**: * *** : .*:*:* *:******** *:**** ******:*:* : :. :: **::: * * ***::*: * ***: * *.* * : . : * ::: : ", "identical_positions": 63, "similar_positions": 46, "identity": "26.58%" }, { "cls_id": "homologset.agr.MGI:1913297", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3Z9K2-1", "uniprot_id": "D3Z9K2_RAT", "id": "D3Z9K2-1", "name": "Large ribosomal subunit protein mL54", "aln": "MAAASLLGATRVWARWHPRALPVPGRPGELFIREYAKKAVSKG---GKGGVAAEALKDPEVCTDPSQLTTHAMGVNIYKEGQEVALKPDSEYPTWLF-QVDLGPPKKLEDLEPESREYWRLLRKQNIWRHNRLSKNKKL---", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9CPW3-1", "uniprot_id": "RM54_MOUSE", "id": "Q9CPW3-1", "name": "Large ribosomal subunit protein mL54", "aln": "MAAAHLLRASRVWARWHPRALPVLRRPGGFSIREYAKKPVGKG---GKGGVAAEALKDPEVCTDPTQLTTHAMGVNIYKEGQDVALKADSEYPTWLF-QVNLGPPKKLEELEPESREYWRLLRKQNIWRHNRLSKNKKL---", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6P161-1", "uniprot_id": "RM54_HUMAN", "id": "Q6P161-1", "name": "Large ribosomal subunit protein mL54", "aln": "MATKRLFGATRTWAGWGAWELLNPATSGRLLARDYAKKPVMKGAKSGKGAVTSEALKDPDVCTDPVQLTTYAMGVNIYKEGQDVPLKPDAEYPEWLF-EMNLGPPKTLEELDPESREYWRRLRKQNIWRHNRLSKNKRL---", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q1LXI5-1", "uniprot_id": "RM54_DANRE", "id": "Q1LXI5-1", "name": "Large ribosomal subunit protein mL54", "aln": "MAHTVLQPFKRINLPVLNAYNNLFCNTFLVQTRSYAKKPVFKG--KGKGMVK-EVLKGPEVCKDPAKLCTYAVGVNVFKQGEDPTIKPKDEYPEWLF-QLNLGPVKQLNELEPDSWEYWRRIRKEHIWRHNKLNKGKKM---", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9W2M8-1", "uniprot_id": "Q9W2M8_DROME", "id": "Q9W2M8-1", "name": "Large ribosomal subunit protein mL54", "aln": "-----MTSLTAVFQMARQRLIAPAIGNWARFYAAKPAAPAGKKKKLGKLGPIMEKKVIP-VETDANKLVNYVCGSNYMKTGEDIKIKPDSEYPDWLW-TLNTEGIVPLDELDPNSKQYWRRLRKLALRRNNQLSKLKKF---", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P36532-1", "uniprot_id": "RM37_YEAST", "id": "P36532-1", "name": "Large ribosomal subunit protein mL54", "aln": "--------------MLARSLGYRLISTSRILYNKPTVKSVVSS------------------CPAGTSLN-----LNIWKSGKDAVALEDKEYPNWLWSVLDSDHVVEHAAEDPEGQALLKRRKNIRKANRQRIKQNNFLSQL", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . .. . .* * * *:: . *** **: :: :*:. : :: ..:::.: : : ", "identical_positions": 10, "similar_positions": 26, "identity": "7.04%" }, { "cls_id": "homologset.agr.MGI:1913298", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9BV81-1", "uniprot_id": "EMC6_HUMAN", "id": "Q9BV81-1", "name": "ER membrane protein complex subunit 6", "aln": "MAAVVAKREGP---PFISEAAVRGNAAVLDYCRTSVSALSGATAGILGLTGLYGFIFYLLASVLLSLLLILKAGRRWN-KYFKS-RRPLFTGGLIGGLFTYVLFWTFLYGMVHVY", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9CQW0-1", "uniprot_id": "EMC6_MOUSE", "id": "Q9CQW0-1", "name": "ER membrane protein complex subunit 6", "aln": "MAAVVAKREGP---PFISEAAVRGNAAVLDYCRTSVSALSGATAGILGLTGLYGFIFYLLASVLLSLLLILKAGRRWN-KYFKS-RRPLFTGGLIGGLFTYVLFWTFLYGMVHVY", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D4ABX9-1", "uniprot_id": "D4ABX9_RAT", "id": "D4ABX9-1", "name": "ER membrane protein complex subunit 6", "aln": "MAAVVAKREGP---PFISEAAVRGNAAVLDYCRTSVSALSGATAGILGLTGLYGFIFYLLASVLLSLLLILKAGRRWN-KYFKS-RRPLFTGGLIGGLFTYVLFWTFLYGMVHVY", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q6P0F0-1", "uniprot_id": "EMC6_DANRE", "id": "Q6P0F0-1", "name": "ER membrane protein complex subunit 6", "aln": "MASVAAKREGP---QFISEVSVRGNGAVLDYCRTSVSALSGATAGILGLTGLYGFVFYFLASFLLSLLLILKAGRRWN-KCFKS-RRLLFTGGLVGGLFTYVLFWTFLYGMVHVY", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VBZ8-1", "uniprot_id": "Q9VBZ8_DROME", "id": "Q9VBZ8-1", "name": "ER membrane protein complex subunit 6", "aln": "MNRVKTTQSKTGEIIAYSEGAIRNNISAVEYCRTSMAAISGCAAGILGLSGTLGFLFYFLSVFVLWILVLVKSGTQWR-KFFIN-RRNLLTNQFMGGLCTYVLFWTFLYGMVHVY", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q12431-1", "uniprot_id": "EMC6_YEAST", "id": "Q12431-1", "name": "ER membrane protein complex subunit 6", "aln": "MSSNEEVFTQIN-----ATANVVDNKKRLLFVQDSSALVLGLVAGFLQIESVHGFIWFLILYNLINVIYIVWICQLQPGKFYQSPLHDIFFESFFREITGFVMAWTFGYALIG--", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* : : .* : : : * : : * .**:* : . **::::: :: :: :: * : . : :: :. : :*: *** *.:: ", "identical_positions": 15, "similar_positions": 36, "identity": "13.04%" }, { "cls_id": "homologset.agr.MGI:1913299", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q4V7D2-1", "uniprot_id": "ROGDI_RAT", "id": "Q4V7D2-1", "name": "Protein rogdi homolog", "aln": "--------MATAMAASAAERAVLEEEFRWLLHAEVHAVLRQLQDILKEASLRFTLP-GPSTEGPAKQENFILGSCGTDQVKGVLTLQGDALSQADVNLKMPRN--NQLLHFAFREDKQWKLQQIQDARNHVSQAIYLLA----NRDESYQFKTGAEVLKLMDAVMLQLTRARNRLTTPATLTLPEIAASGLTRMFAPTLPSDLLVNVYINLNKLCLTVYQLHTLQPTSTKNFRPAGGAVLHSPGAMFEWGSQRLEVSHVHKVECVIPWLNDALVYFTVSLQ------------LCQQLKDKISVFSSYWSS-----RPF--------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q3TDK6-1", "uniprot_id": "ROGDI_MOUSE", "id": "Q3TDK6-1", "name": "Protein rogdi homolog", "aln": "--------MATAMAASAAERAVLEEEFRWLLHAEVHAVLRQLQDILKEASLRFTLP-GPSTEGPAKQENFILGSCGTDQVKGTLTLQGDALSQADVNLKMPRN--NQLLHLAFREDKQWKLQQIQDARNHVSQAIYLLA----NRDESYQFKTGAEVLKLMDAVMLQLTRARSRLTTPATLTLPEIAASGLTRMFAPTLPSDLLVNVYINLNKLCLTVYQLHALQPTSTKNFRPAGGAVLHSPGAMFEWGSQRLEVSHVHKVECVIPWLNDALVYFTVSLQ------------LCQQLKDKIAVFSSYWSS-----RPF--------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9GZN7-1", "uniprot_id": "ROGDI_HUMAN", "id": "Q9GZN7-1", "name": "Protein rogdi homolog", "aln": "--------MATVMAATAAERAVLEEEFRWLLHDEVHAVLKQLQDILKEASLRFTLP-GSGTEGPAKQENFILGSCGTDQVKGVLTLQGDALSQADVNLKMPRN--NQLLHFAFREDKQWKLQQIQDARNHVSQAIYLLT----SRDQSYQFKTGAEVLKLMDAVMLQLTRARNRLTTPATLTLPEIAASGLTRMFAPALPSDLLVNVYINLNKLCLTVYQLHALQPNSTKNFRPAGGAVLHSPGAMFEWGSQRLEVSHVHKVECVIPWLNDALVYFTVSLQ------------LCQQLKDKISVFSSYWSY-----RPF--------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q7ZVT5-1", "uniprot_id": "ROGDI_DANRE", "id": "Q7ZVT5-1", "name": "Protein rogdi homolog", "aln": "-----------MTAASQAERTVLEEEFNWLLKEEVHAVLKQLQDILKEASRRLSMP-SPGLEGQLKQENFILGSSTMDQVKGVLTLQGEALTQADINIKVAKS--SQVMHFAFRDDKQWKLQQIQDARNHVNQALQLLS----SRDDSYHFKTGAEVNKLMDAIMLQLTRARNRLTTPASMTLPELAASGLMKMFTPPMPGDVMVNFYINLSKLCLTVYQLHVLQPNTTKNFKPAGSSVLHNPGAMFEHNNTKFEVSHVHKVECVVPWLNDTLVFFTISLQ------------LCQQLKDKISVFSSFWNY-----RPF--------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VVE2-1", "uniprot_id": "ROGDI_DROME", "id": "Q9VVE2-1", "name": "Protein rogdi", "aln": "--------MKMLADTEREEALNLQIEFEWVLRQEVHAILKQLRSILVECAHRFPVP-LYENEG-KKTEKFIL-TVSPDQLKAVLTLTGDAITQADISFKLCKAP-SQTQRTSITHDSPWKLQQVQDAANHLQTAINHID----DVDDSYHFKTSDEVLHVIGNILDALQRGRNSLLVPKKKPIDELIKGRNMKSLVPNLPEDLAVSFYLQSHKLIIAVYQLLNNQ------------------------GTMRFDS---RQAEASVQWLNDVLLLLMNGQK------------LCQQLKDKISVFSVYKDFTVGSRSPSALSY----------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q03956-1", "uniprot_id": "RAV2_YEAST", "id": "Q03956-1", "name": "Regulator of V-ATPase in vacuolar membrane protein 2", "aln": "MSVDLFPNDRFGAEDKYDNFKDAVKECSWLIEEIVKPQLPNIIDNFSKCLEMLESDQIFKMPVSNGIPNESNKQNDSPTVKGVITRQGQYIVDFHIVVRFPQFQRGKQVMFRMNTGLNFLLIQFSKIMTHLKNILEILNQLQVATDVSEFVSKFGVAMELLNHSLILLQNPPRDLVFPEDNNFAMKEMFQDCYSVCESTAHILGLELTLCRNELCIELRNLIKVTKKPWCEIDSKTGRSFCDQIRNQVTNERNKTLSKILSENGVQVQDSTLLNHIISSFQSEAITLPEAQELLRRGVTFDNRVVMECEKLIVSTSDPTLISISAKLNSLKASMANHQANLVASKQLSTYK", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : * *::. *:. * :: . : :. : : :*..:* *: : : .: .:. : .: : . : * *... .*:. : : * * ... . .::. : * . * * : . . : :.. : :* : : :* . . . : . * : . : * : :. . *. . * ", "identical_positions": 21, "similar_positions": 76, "identity": "5.98%" } ]